SMALA_RS21835 900012d11112a9243a7e1a6c5648a7a8 554 Gene3D G3DSA:3.40.50.10090 434 528 3.2E-22 T 29-03-2018 SMALA_RS21835 900012d11112a9243a7e1a6c5648a7a8 554 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 13 228 8.8E-33 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMALA_RS21835 900012d11112a9243a7e1a6c5648a7a8 554 Gene3D G3DSA:3.40.50.10090 305 433 1.8E-27 T 29-03-2018 SMALA_RS21835 900012d11112a9243a7e1a6c5648a7a8 554 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 17 31 - T 29-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 SMALA_RS21835 900012d11112a9243a7e1a6c5648a7a8 554 SUPERFAMILY SSF53790 9 276 1.57E-43 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMALA_RS21835 900012d11112a9243a7e1a6c5648a7a8 554 Pfam PF02602 Uroporphyrinogen-III synthase HemD 287 514 2.3E-62 T 29-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMALA_RS21835 900012d11112a9243a7e1a6c5648a7a8 554 Gene3D G3DSA:3.30.950.10 147 288 2.2E-25 T 29-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMALA_RS21835 900012d11112a9243a7e1a6c5648a7a8 554 Gene3D G3DSA:3.40.1010.10 11 146 8.1E-30 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMALA_RS21835 900012d11112a9243a7e1a6c5648a7a8 554 SUPERFAMILY SSF69618 273 523 4.19E-64 T 29-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMALA_RS19410 ba7831420b619d2858ec353039a16905 1260 Gene3D G3DSA:1.20.1560.10 6 320 4.6E-53 T 29-03-2018 SMALA_RS19410 ba7831420b619d2858ec353039a16905 1260 Pfam PF00664 ABC transporter transmembrane region 687 935 5.7E-7 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMALA_RS19410 ba7831420b619d2858ec353039a16905 1260 Pfam PF00664 ABC transporter transmembrane region 22 276 3.5E-34 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMALA_RS19410 ba7831420b619d2858ec353039a16905 1260 Pfam PF00005 ABC transporter 354 501 3.6E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS19410 ba7831420b619d2858ec353039a16905 1260 Pfam PF00005 ABC transporter 1021 1168 2.5E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS19410 ba7831420b619d2858ec353039a16905 1260 TIGRFAM TIGR02857 CydD: thiol reductant ABC exporter, CydD subunit 16 543 8.2E-214 T 29-03-2018 IPR014216 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD GO:0005524|GO:0016020|GO:0042883 SMALA_RS19410 ba7831420b619d2858ec353039a16905 1260 SUPERFAMILY SSF52540 332 544 7.76E-66 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS19410 ba7831420b619d2858ec353039a16905 1260 ProSitePatterns PS00211 ABC transporters family signature. 473 487 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS19410 ba7831420b619d2858ec353039a16905 1260 SUPERFAMILY SSF52540 998 1237 1.51E-68 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS19410 ba7831420b619d2858ec353039a16905 1260 SUPERFAMILY SSF90123 2 328 2.09E-60 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMALA_RS19410 ba7831420b619d2858ec353039a16905 1260 ProSitePatterns PS00211 ABC transporters family signature. 1141 1155 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS19410 ba7831420b619d2858ec353039a16905 1260 SUPERFAMILY SSF90123 677 988 2.62E-43 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMALA_RS19410 ba7831420b619d2858ec353039a16905 1260 Gene3D G3DSA:1.20.1560.10 660 987 6.4E-34 T 29-03-2018 SMALA_RS19410 ba7831420b619d2858ec353039a16905 1260 TIGRFAM TIGR02868 CydC: thiol reductant ABC exporter, CydC subunit 678 1199 2.1E-202 T 29-03-2018 IPR014223 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC GO:0006810|GO:0016021|GO:0042626 SMALA_RS19410 ba7831420b619d2858ec353039a16905 1260 SMART SM00382 1029 1215 7.6E-18 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS19410 ba7831420b619d2858ec353039a16905 1260 SMART SM00382 361 547 6.1E-18 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS19410 ba7831420b619d2858ec353039a16905 1260 Gene3D G3DSA:3.40.50.300 988 1245 6.8E-63 T 29-03-2018 SMALA_RS19410 ba7831420b619d2858ec353039a16905 1260 Gene3D G3DSA:3.40.50.300 321 570 2.7E-61 T 29-03-2018 SMALA_RS19960 084d7566a06dbe081242b2091ac73f37 197 Gene3D G3DSA:1.10.357.10 61 197 4.7E-23 T 29-03-2018 SMALA_RS19960 084d7566a06dbe081242b2091ac73f37 197 Gene3D G3DSA:1.10.10.60 2 60 4.7E-18 T 29-03-2018 SMALA_RS19960 084d7566a06dbe081242b2091ac73f37 197 SUPERFAMILY SSF46689 2 74 2.82E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS19960 084d7566a06dbe081242b2091ac73f37 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 58 1.4E-15 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS19960 084d7566a06dbe081242b2091ac73f37 197 SUPERFAMILY SSF48498 82 194 6.02E-19 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS19960 084d7566a06dbe081242b2091ac73f37 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 2.2E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS19960 084d7566a06dbe081242b2091ac73f37 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 2.2E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS33545 b02317166e033d23f6974009d476e070 236 SUPERFAMILY SSF140959 9 228 1.79E-51 T 29-03-2018 SMALA_RS33545 b02317166e033d23f6974009d476e070 236 Pfam PF03301 Tryptophan 2,3-dioxygenase 6 164 3.4E-24 T 29-03-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 SMALA_RS26510 9f360e1c5124509d64524fa36feb1068 948 Gene3D G3DSA:3.40.50.980 188 361 1.5E-26 T 29-03-2018 SMALA_RS26510 9f360e1c5124509d64524fa36feb1068 948 SMART SM00823 Phosphopantetheine attachment site 583 656 1.8E-6 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS26510 9f360e1c5124509d64524fa36feb1068 948 Gene3D G3DSA:3.40.50.980 16 187 2.2E-25 T 29-03-2018 SMALA_RS26510 9f360e1c5124509d64524fa36feb1068 948 Gene3D G3DSA:3.40.50.1820 664 933 4.2E-25 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS26510 9f360e1c5124509d64524fa36feb1068 948 Gene3D G3DSA:1.10.1200.10 589 663 5.6E-17 T 29-03-2018 SMALA_RS26510 9f360e1c5124509d64524fa36feb1068 948 Gene3D G3DSA:2.30.38.10 362 443 5.0E-25 T 29-03-2018 SMALA_RS26510 9f360e1c5124509d64524fa36feb1068 948 SUPERFAMILY SSF53474 659 932 2.27E-56 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS26510 9f360e1c5124509d64524fa36feb1068 948 Gene3D G3DSA:3.30.300.30 446 588 2.3E-12 T 29-03-2018 SMALA_RS26510 9f360e1c5124509d64524fa36feb1068 948 SUPERFAMILY SSF56801 13 556 5.89E-103 T 29-03-2018 SMALA_RS26510 9f360e1c5124509d64524fa36feb1068 948 SMART SM00824 Thioesterase 679 925 3.6E-4 T 29-03-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 SMALA_RS26510 9f360e1c5124509d64524fa36feb1068 948 ProSitePatterns PS00455 Putative AMP-binding domain signature. 182 193 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS26510 9f360e1c5124509d64524fa36feb1068 948 Pfam PF00550 Phosphopantetheine attachment site 586 652 1.8E-9 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS26510 9f360e1c5124509d64524fa36feb1068 948 SUPERFAMILY SSF47336 578 671 2.22E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS26510 9f360e1c5124509d64524fa36feb1068 948 Pfam PF00501 AMP-binding enzyme 45 450 2.1E-68 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS26510 9f360e1c5124509d64524fa36feb1068 948 Pfam PF00975 Thioesterase domain 677 780 4.9E-30 T 29-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 SMALA_RS32590 3780b8bf2ff3f1d9a0a3fe8b27a2de35 406 Pfam PF13241 Putative NAD(P)-binding 11 118 4.5E-19 T 29-03-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 SMALA_RS32590 3780b8bf2ff3f1d9a0a3fe8b27a2de35 406 PIRSF PIRSF036426 4 156 2.8E-29 T 29-03-2018 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 SMALA_RS32590 3780b8bf2ff3f1d9a0a3fe8b27a2de35 406 PIRSF PIRSF036426 150 406 2.3E-95 T 29-03-2018 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 SMALA_RS32590 3780b8bf2ff3f1d9a0a3fe8b27a2de35 406 SUPERFAMILY SSF53790 163 401 6.54E-74 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMALA_RS32590 3780b8bf2ff3f1d9a0a3fe8b27a2de35 406 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 8 132 1.8E-19 T 29-03-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 SMALA_RS32590 3780b8bf2ff3f1d9a0a3fe8b27a2de35 406 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 244 277 - T 29-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 SMALA_RS32590 3780b8bf2ff3f1d9a0a3fe8b27a2de35 406 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 166 377 1.9E-48 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMALA_RS32590 3780b8bf2ff3f1d9a0a3fe8b27a2de35 406 Gene3D G3DSA:3.40.1010.10 164 288 1.6E-36 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMALA_RS32590 3780b8bf2ff3f1d9a0a3fe8b27a2de35 406 SUPERFAMILY SSF51735 7 110 5.07E-18 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS32590 3780b8bf2ff3f1d9a0a3fe8b27a2de35 406 Gene3D G3DSA:3.30.950.10 289 405 6.5E-37 T 29-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMALA_RS32590 3780b8bf2ff3f1d9a0a3fe8b27a2de35 406 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 165 401 2.8E-84 T 29-03-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0006779|GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 SMALA_RS32590 3780b8bf2ff3f1d9a0a3fe8b27a2de35 406 Gene3D G3DSA:3.40.50.720 6 133 4.6E-19 T 29-03-2018 SMALA_RS35545 e97e461ecb06f051b7820037a04b04d8 393 Pfam PF07728 AAA domain (dynein-related subfamily) 129 285 6.3E-5 T 29-03-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 SMALA_RS35545 e97e461ecb06f051b7820037a04b04d8 393 Gene3D G3DSA:3.40.50.300 114 351 1.0E-22 T 29-03-2018 SMALA_RS35545 e97e461ecb06f051b7820037a04b04d8 393 SUPERFAMILY SSF52540 117 253 1.93E-23 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS35545 e97e461ecb06f051b7820037a04b04d8 393 SUPERFAMILY SSF52540 280 346 1.93E-23 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS35545 e97e461ecb06f051b7820037a04b04d8 393 SMART SM00382 125 317 7.8E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS28135 3b09047b9b067f0b5912fcb4d091d71e 147 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 2 77 23.804 T 29-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS28135 3b09047b9b067f0b5912fcb4d091d71e 147 TIGRFAM TIGR00002 S16: ribosomal protein bS16 3 79 2.1E-32 T 29-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS28135 3b09047b9b067f0b5912fcb4d091d71e 147 ProSitePatterns PS00732 Ribosomal protein S16 signature. 3 12 - T 29-03-2018 IPR020592 Ribosomal protein S16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS28135 3b09047b9b067f0b5912fcb4d091d71e 147 Pfam PF00886 Ribosomal protein S16 9 67 8.9E-24 T 29-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS28135 3b09047b9b067f0b5912fcb4d091d71e 147 Gene3D G3DSA:3.30.1320.10 2 84 6.9E-31 T 29-03-2018 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS28135 3b09047b9b067f0b5912fcb4d091d71e 147 SUPERFAMILY SSF54565 2 98 2.49E-33 T 29-03-2018 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS27920 d9834bcb0ba645ebb0bb67b14e24a9f7 476 Gene3D G3DSA:3.40.1060.10 153 288 6.7E-44 T 29-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS27920 d9834bcb0ba645ebb0bb67b14e24a9f7 476 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 1 466 59.458 T 29-03-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 SMALA_RS27920 d9834bcb0ba645ebb0bb67b14e24a9f7 476 Gene3D G3DSA:3.30.499.10 325 474 3.3E-49 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS27920 d9834bcb0ba645ebb0bb67b14e24a9f7 476 SUPERFAMILY SSF53732 1 465 1.57E-161 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS27920 d9834bcb0ba645ebb0bb67b14e24a9f7 476 Gene3D G3DSA:3.30.499.10 1 152 7.0E-40 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS27920 d9834bcb0ba645ebb0bb67b14e24a9f7 476 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 1 460 2.1E-225 T 29-03-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 SMALA_RS27920 d9834bcb0ba645ebb0bb67b14e24a9f7 476 PRINTS PR00415 Aconitase family signature 108 116 6.2E-47 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS27920 d9834bcb0ba645ebb0bb67b14e24a9f7 476 PRINTS PR00415 Aconitase family signature 343 354 6.2E-47 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS27920 d9834bcb0ba645ebb0bb67b14e24a9f7 476 PRINTS PR00415 Aconitase family signature 286 300 6.2E-47 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS27920 d9834bcb0ba645ebb0bb67b14e24a9f7 476 PRINTS PR00415 Aconitase family signature 209 222 6.2E-47 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS27920 d9834bcb0ba645ebb0bb67b14e24a9f7 476 PRINTS PR00415 Aconitase family signature 133 148 6.2E-47 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS27920 d9834bcb0ba645ebb0bb67b14e24a9f7 476 PRINTS PR00415 Aconitase family signature 195 208 6.2E-47 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS27920 d9834bcb0ba645ebb0bb67b14e24a9f7 476 PRINTS PR00415 Aconitase family signature 119 132 6.2E-47 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS27920 d9834bcb0ba645ebb0bb67b14e24a9f7 476 PRINTS PR00415 Aconitase family signature 399 412 6.2E-47 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS27920 d9834bcb0ba645ebb0bb67b14e24a9f7 476 PRINTS PR00415 Aconitase family signature 82 95 6.2E-47 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS27920 d9834bcb0ba645ebb0bb67b14e24a9f7 476 ProSitePatterns PS00450 Aconitase family signature 1. 339 355 - T 29-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 SMALA_RS27920 d9834bcb0ba645ebb0bb67b14e24a9f7 476 Pfam PF00330 Aconitase family (aconitate hydratase) 7 457 1.2E-154 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS27920 d9834bcb0ba645ebb0bb67b14e24a9f7 476 ProSitePatterns PS01244 Aconitase family signature 2. 399 412 - T 29-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 SMALA_RS00355 b4fa004dfaaaf3eacccdd0446e163eea 350 PIRSF PIRSF016578 1 213 1.1E-9 T 29-03-2018 SMALA_RS00355 b4fa004dfaaaf3eacccdd0446e163eea 350 PIRSF PIRSF016578 218 336 0.013 T 29-03-2018 SMALA_RS00355 b4fa004dfaaaf3eacccdd0446e163eea 350 Gene3D G3DSA:2.40.110.10 118 215 2.6E-6 T 29-03-2018 SMALA_RS00355 b4fa004dfaaaf3eacccdd0446e163eea 350 SUPERFAMILY SSF56645 6 213 2.54E-27 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMALA_RS00355 b4fa004dfaaaf3eacccdd0446e163eea 350 Gene3D G3DSA:1.10.540.10 1 115 8.7E-15 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS00355 b4fa004dfaaaf3eacccdd0446e163eea 350 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 110 2.8E-8 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS15025 6c0bcc3832b2ab46fb223e3c7fe03bec 684 Gene3D G3DSA:3.40.50.300 449 658 7.5E-43 T 29-03-2018 SMALA_RS15025 6c0bcc3832b2ab46fb223e3c7fe03bec 684 Pfam PF03412 Peptidase C39 family 2 115 5.1E-10 T 29-03-2018 IPR005074 Peptidase C39, bacteriocin processing GO:0005524|GO:0006508|GO:0008233|GO:0016021 SMALA_RS15025 6c0bcc3832b2ab46fb223e3c7fe03bec 684 SUPERFAMILY SSF52540 459 657 4.82E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS15025 6c0bcc3832b2ab46fb223e3c7fe03bec 684 SUPERFAMILY SSF90123 136 441 1.31E-48 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMALA_RS15025 6c0bcc3832b2ab46fb223e3c7fe03bec 684 SMART SM00382 491 684 4.7E-6 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS15025 6c0bcc3832b2ab46fb223e3c7fe03bec 684 Pfam PF00005 ABC transporter 484 629 1.4E-21 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS15025 6c0bcc3832b2ab46fb223e3c7fe03bec 684 Gene3D G3DSA:3.90.70.10 1 120 6.4E-16 T 29-03-2018 SMALA_RS15025 6c0bcc3832b2ab46fb223e3c7fe03bec 684 Gene3D G3DSA:1.20.1560.10 130 443 4.8E-36 T 29-03-2018 SMALA_RS15025 6c0bcc3832b2ab46fb223e3c7fe03bec 684 Pfam PF00664 ABC transporter transmembrane region 147 417 7.8E-35 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMALA_RS38635 3455945da9769214b957b62e2bb95f57 606 SUPERFAMILY SSF51011 390 473 2.72E-18 T 29-03-2018 SMALA_RS38635 3455945da9769214b957b62e2bb95f57 606 SUPERFAMILY SSF51445 51 159 4.92E-58 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS38635 3455945da9769214b957b62e2bb95f57 606 SUPERFAMILY SSF51445 197 385 4.92E-58 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS38635 3455945da9769214b957b62e2bb95f57 606 Gene3D G3DSA:2.60.40.1180 388 477 2.9E-24 T 29-03-2018 SMALA_RS38635 3455945da9769214b957b62e2bb95f57 606 Gene3D G3DSA:2.60.120.260 478 606 8.4E-30 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS38635 3455945da9769214b957b62e2bb95f57 606 Pfam PF16990 Carbohydrate binding module (family 35) 486 593 3.5E-9 T 29-03-2018 IPR005084 Carbohydrate binding module family 6 GO:0030246 SMALA_RS38635 3455945da9769214b957b62e2bb95f57 606 PRINTS PR00740 Glycosyl hydrolase family 27 signature 246 264 3.7E-14 T 29-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 SMALA_RS38635 3455945da9769214b957b62e2bb95f57 606 PRINTS PR00740 Glycosyl hydrolase family 27 signature 48 67 3.7E-14 T 29-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 SMALA_RS38635 3455945da9769214b957b62e2bb95f57 606 PRINTS PR00740 Glycosyl hydrolase family 27 signature 95 110 3.7E-14 T 29-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 SMALA_RS38635 3455945da9769214b957b62e2bb95f57 606 PRINTS PR00740 Glycosyl hydrolase family 27 signature 318 337 3.7E-14 T 29-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 SMALA_RS38635 3455945da9769214b957b62e2bb95f57 606 Pfam PF16499 Alpha galactosidase A 203 385 7.6E-22 T 29-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 SMALA_RS38635 3455945da9769214b957b62e2bb95f57 606 Pfam PF16499 Alpha galactosidase A 54 189 1.2E-15 T 29-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 SMALA_RS38635 3455945da9769214b957b62e2bb95f57 606 Gene3D G3DSA:3.20.20.70 43 387 1.9E-69 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS38635 3455945da9769214b957b62e2bb95f57 606 SUPERFAMILY SSF49785 486 602 6.07E-16 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS39945 a38be568724623865133f19521ce9ac8 296 Gene3D G3DSA:1.10.260.40 2 102 3.2E-12 T 29-03-2018 SMALA_RS39945 a38be568724623865133f19521ce9ac8 296 SMART SM00530 9 86 2.7E-5 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS39945 a38be568724623865133f19521ce9ac8 296 SUPERFAMILY SSF47413 35 83 1.86E-6 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS39945 a38be568724623865133f19521ce9ac8 296 Pfam PF13560 Helix-turn-helix domain 17 89 1.6E-12 T 29-03-2018 SMALA_RS35445 53a249071f505d6e082d4914f103fc50 329 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 130 5.4E-33 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS35445 53a249071f505d6e082d4914f103fc50 329 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 57 71 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 SMALA_RS35445 53a249071f505d6e082d4914f103fc50 329 Pfam PF00107 Zinc-binding dehydrogenase 171 280 2.7E-10 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMALA_RS35445 53a249071f505d6e082d4914f103fc50 329 Gene3D G3DSA:3.40.50.720 142 304 4.6E-18 T 29-03-2018 SMALA_RS35445 53a249071f505d6e082d4914f103fc50 329 SUPERFAMILY SSF50129 1 138 3.65E-54 T 29-03-2018 IPR011032 GroES-like SMALA_RS35445 53a249071f505d6e082d4914f103fc50 329 SUPERFAMILY SSF50129 300 327 3.65E-54 T 29-03-2018 IPR011032 GroES-like SMALA_RS35445 53a249071f505d6e082d4914f103fc50 329 Gene3D G3DSA:3.90.180.10 1 141 7.5E-50 T 29-03-2018 SMALA_RS35445 53a249071f505d6e082d4914f103fc50 329 SMART SM00829 7 327 1.2E-4 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS35445 53a249071f505d6e082d4914f103fc50 329 SUPERFAMILY SSF51735 137 299 6.06E-23 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS16025 01133de4bc751c792cae80ccea1868b6 315 Pfam PF04542 Sigma-70 region 2 94 163 1.6E-16 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS16025 01133de4bc751c792cae80ccea1868b6 315 PRINTS PR00046 Major sigma-70 factor signature 281 296 5.9E-12 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS16025 01133de4bc751c792cae80ccea1868b6 315 PRINTS PR00046 Major sigma-70 factor signature 118 131 5.9E-12 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS16025 01133de4bc751c792cae80ccea1868b6 315 PRINTS PR00046 Major sigma-70 factor signature 264 276 5.9E-12 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS16025 01133de4bc751c792cae80ccea1868b6 315 PRINTS PR00046 Major sigma-70 factor signature 296 307 5.9E-12 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS16025 01133de4bc751c792cae80ccea1868b6 315 Gene3D G3DSA:1.10.601.10 54 162 1.4E-24 T 29-03-2018 SMALA_RS16025 01133de4bc751c792cae80ccea1868b6 315 SUPERFAMILY SSF88946 56 163 6.12E-31 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS16025 01133de4bc751c792cae80ccea1868b6 315 SUPERFAMILY SSF88659 230 311 1.76E-15 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS16025 01133de4bc751c792cae80ccea1868b6 315 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 89 310 1.1E-92 T 29-03-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS16025 01133de4bc751c792cae80ccea1868b6 315 Pfam PF04539 Sigma-70 region 3 174 240 5.1E-15 T 29-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS16025 01133de4bc751c792cae80ccea1868b6 315 Gene3D G3DSA:1.10.10.10 164 216 4.8E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS16025 01133de4bc751c792cae80ccea1868b6 315 Pfam PF04545 Sigma-70, region 4 261 309 6.7E-18 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS16025 01133de4bc751c792cae80ccea1868b6 315 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 118 131 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS16025 01133de4bc751c792cae80ccea1868b6 315 SUPERFAMILY SSF88659 167 242 2.14E-14 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS16025 01133de4bc751c792cae80ccea1868b6 315 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 91 310 3.0E-32 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS16025 01133de4bc751c792cae80ccea1868b6 315 Gene3D G3DSA:1.10.10.10 252 314 7.4E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS08195 95fbedc61a33a903c5b9898a43437890 632 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 4 277 2.1E-105 T 29-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SMALA_RS08195 95fbedc61a33a903c5b9898a43437890 632 Gene3D G3DSA:3.40.50.970 292 484 3.7E-50 T 29-03-2018 SMALA_RS08195 95fbedc61a33a903c5b9898a43437890 632 Pfam PF02780 Transketolase, C-terminal domain 492 607 2.4E-26 T 29-03-2018 IPR033248 Transketolase, C-terminal domain SMALA_RS08195 95fbedc61a33a903c5b9898a43437890 632 Gene3D G3DSA:3.40.50.920 488 617 7.2E-29 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMALA_RS08195 95fbedc61a33a903c5b9898a43437890 632 SUPERFAMILY SSF52518 2 343 3.71E-70 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold SMALA_RS08195 95fbedc61a33a903c5b9898a43437890 632 ProSitePatterns PS00801 Transketolase signature 1. 29 48 - T 29-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SMALA_RS08195 95fbedc61a33a903c5b9898a43437890 632 Gene3D G3DSA:3.40.50.970 7 291 2.9E-69 T 29-03-2018 SMALA_RS08195 95fbedc61a33a903c5b9898a43437890 632 Pfam PF02779 Transketolase, pyrimidine binding domain 313 473 2.7E-35 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain SMALA_RS08195 95fbedc61a33a903c5b9898a43437890 632 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 6 616 2.7E-181 T 29-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SMALA_RS08195 95fbedc61a33a903c5b9898a43437890 632 SMART SM00861 313 477 2.6E-53 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain SMALA_RS08195 95fbedc61a33a903c5b9898a43437890 632 ProSitePatterns PS00802 Transketolase signature 2. 419 435 - T 29-03-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SMALA_RS08195 95fbedc61a33a903c5b9898a43437890 632 SUPERFAMILY SSF52922 493 613 4.97E-24 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMALA_RS08195 95fbedc61a33a903c5b9898a43437890 632 SUPERFAMILY SSF52518 292 475 9.25E-53 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold SMALA_RS08195 95fbedc61a33a903c5b9898a43437890 632 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 3 617 40.529 T 29-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SMALA_RS05645 ecf3eed17b0b98e7556e199b2a1084f2 308 SUPERFAMILY SSF53850 96 305 6.42E-42 T 29-03-2018 SMALA_RS05645 ecf3eed17b0b98e7556e199b2a1084f2 308 Pfam PF03466 LysR substrate binding domain 95 301 4.0E-42 T 29-03-2018 IPR005119 LysR, substrate-binding SMALA_RS05645 ecf3eed17b0b98e7556e199b2a1084f2 308 Gene3D G3DSA:3.40.190.10 185 275 2.7E-21 T 29-03-2018 SMALA_RS05645 ecf3eed17b0b98e7556e199b2a1084f2 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 35 45 1.5E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS05645 ecf3eed17b0b98e7556e199b2a1084f2 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 45 56 1.5E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS05645 ecf3eed17b0b98e7556e199b2a1084f2 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 35 1.5E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS05645 ecf3eed17b0b98e7556e199b2a1084f2 308 Gene3D G3DSA:3.40.190.10 95 184 3.1E-24 T 29-03-2018 SMALA_RS05645 ecf3eed17b0b98e7556e199b2a1084f2 308 SUPERFAMILY SSF46785 7 118 3.05E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS05645 ecf3eed17b0b98e7556e199b2a1084f2 308 Gene3D G3DSA:1.10.10.10 2 93 4.5E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS05645 ecf3eed17b0b98e7556e199b2a1084f2 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 69 1.3E-19 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS26940 a77fef278c7c65c47f845b003ac1180f 377 SUPERFAMILY SSF55874 267 363 1.95E-9 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS26940 a77fef278c7c65c47f845b003ac1180f 377 Gene3D G3DSA:3.30.565.10 228 376 3.9E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS26940 a77fef278c7c65c47f845b003ac1180f 377 Pfam PF07730 Histidine kinase 161 224 8.6E-15 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMALA_RS13425 54c09f6863522e169daf628f8cab9177 411 SMART SM00418 18 99 0.0038 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS13425 54c09f6863522e169daf628f8cab9177 411 Gene3D G3DSA:3.30.420.40 215 408 1.6E-51 T 29-03-2018 SMALA_RS13425 54c09f6863522e169daf628f8cab9177 411 SUPERFAMILY SSF53067 96 396 3.94E-38 T 29-03-2018 SMALA_RS13425 54c09f6863522e169daf628f8cab9177 411 Gene3D G3DSA:3.30.420.40 84 214 1.1E-24 T 29-03-2018 SMALA_RS13425 54c09f6863522e169daf628f8cab9177 411 Pfam PF12802 MarR family 26 71 2.8E-7 T 29-03-2018 SMALA_RS13425 54c09f6863522e169daf628f8cab9177 411 Gene3D G3DSA:1.10.10.10 25 83 4.5E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS13425 54c09f6863522e169daf628f8cab9177 411 Pfam PF00480 ROK family 103 364 1.9E-28 T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 SMALA_RS13425 54c09f6863522e169daf628f8cab9177 411 SUPERFAMILY SSF46785 21 86 8.04E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS01085 b9fb1d5f1083004572a916cf7d7be242 278 Gene3D G3DSA:3.40.930.10 2 149 3.0E-31 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 SMALA_RS01085 b9fb1d5f1083004572a916cf7d7be242 278 SUPERFAMILY SSF52794 186 275 1.26E-11 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 SMALA_RS01085 b9fb1d5f1083004572a916cf7d7be242 278 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 187 272 1.5E-8 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 SMALA_RS01085 b9fb1d5f1083004572a916cf7d7be242 278 SUPERFAMILY SSF55804 4 148 8.24E-33 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 SMALA_RS01085 b9fb1d5f1083004572a916cf7d7be242 278 Gene3D G3DSA:3.40.50.2300 185 278 4.9E-12 T 29-03-2018 SMALA_RS01085 b9fb1d5f1083004572a916cf7d7be242 278 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 7 147 3.2E-28 T 29-03-2018 IPR002178 PTS EIIA type-2 domain SMALA_RS06060 f3c26e3a9da94342eb7ebac5e53cace9 164 SUPERFAMILY SSF50475 2 155 1.94E-35 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS06060 f3c26e3a9da94342eb7ebac5e53cace9 164 Pfam PF01613 Flavin reductase like domain 11 155 2.2E-31 T 29-03-2018 IPR002563 Flavin reductase like domain GO:0010181 SMALA_RS06060 f3c26e3a9da94342eb7ebac5e53cace9 164 SMART SM00903 11 156 2.2E-37 T 29-03-2018 IPR002563 Flavin reductase like domain GO:0010181 SMALA_RS06060 f3c26e3a9da94342eb7ebac5e53cace9 164 Gene3D G3DSA:2.30.110.10 2 156 3.2E-36 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS25110 666d7c1ae8c6acd2f06e092dbd72eb73 215 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 88 190 2.5E-6 T 29-03-2018 SMALA_RS25110 666d7c1ae8c6acd2f06e092dbd72eb73 215 SUPERFAMILY SSF46689 5 84 2.46E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS25110 666d7c1ae8c6acd2f06e092dbd72eb73 215 SUPERFAMILY SSF48498 88 190 1.93E-6 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS25110 666d7c1ae8c6acd2f06e092dbd72eb73 215 Gene3D G3DSA:1.10.357.10 68 190 7.2E-14 T 29-03-2018 SMALA_RS25110 666d7c1ae8c6acd2f06e092dbd72eb73 215 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 4.6E-13 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS25110 666d7c1ae8c6acd2f06e092dbd72eb73 215 Gene3D G3DSA:1.10.10.60 1 37 3.6E-10 T 29-03-2018 SMALA_RS25110 666d7c1ae8c6acd2f06e092dbd72eb73 215 Gene3D G3DSA:1.10.260.40 38 67 5.0E-8 T 29-03-2018 SMALA_RS25110 666d7c1ae8c6acd2f06e092dbd72eb73 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 1.8E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS25110 666d7c1ae8c6acd2f06e092dbd72eb73 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 1.8E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS19295 8a784c6494686db493544cdba86467a3 219 SUPERFAMILY SSF52833 54 215 2.41E-34 T 29-03-2018 IPR012336 Thioredoxin-like fold SMALA_RS19295 8a784c6494686db493544cdba86467a3 219 Pfam PF02630 SCO1/SenC 51 180 2.5E-23 T 29-03-2018 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMALA_RS19295 8a784c6494686db493544cdba86467a3 219 Gene3D G3DSA:3.40.30.10 47 217 4.5E-25 T 29-03-2018 SMALA_RS20145 93bbc7883faa553f87b04ee30f73a71d 712 Gene3D G3DSA:3.30.450.40 133 301 8.6E-21 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS20145 93bbc7883faa553f87b04ee30f73a71d 712 SUPERFAMILY SSF55781 157 306 4.14E-13 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS20145 93bbc7883faa553f87b04ee30f73a71d 712 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 350 565 1.4E-46 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS20145 93bbc7883faa553f87b04ee30f73a71d 712 Pfam PF13185 GAF domain 187 293 5.1E-10 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS20145 93bbc7883faa553f87b04ee30f73a71d 712 SMART SM00331 321 565 4.7E-39 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS20145 93bbc7883faa553f87b04ee30f73a71d 712 SUPERFAMILY SSF81606 337 564 2.88E-7 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS20145 93bbc7883faa553f87b04ee30f73a71d 712 Gene3D G3DSA:3.60.40.10 302 568 1.9E-39 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS20145 93bbc7883faa553f87b04ee30f73a71d 712 Pfam PF13581 Histidine kinase-like ATPase domain 588 698 2.2E-7 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS20145 93bbc7883faa553f87b04ee30f73a71d 712 Gene3D G3DSA:3.30.450.20 1 118 3.4E-8 T 29-03-2018 SMALA_RS20145 93bbc7883faa553f87b04ee30f73a71d 712 Gene3D G3DSA:3.30.565.10 578 710 8.2E-10 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS36700 b9dbc4f72fd4e2e273c6591e5b2d80db 2246 Gene3D G3DSA:3.90.180.10 1724 1790 0.0029 T 29-03-2018 SMALA_RS36700 b9dbc4f72fd4e2e273c6591e5b2d80db 2246 Pfam PF00698 Acyl transferase domain 579 902 2.9E-81 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS36700 b9dbc4f72fd4e2e273c6591e5b2d80db 2246 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 424 540 1.3E-12 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS36700 b9dbc4f72fd4e2e273c6591e5b2d80db 2246 SMART SM00829 1480 1787 6.8E-179 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS36700 b9dbc4f72fd4e2e273c6591e5b2d80db 2246 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 1500 1555 1.3E-6 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS36700 b9dbc4f72fd4e2e273c6591e5b2d80db 2246 SUPERFAMILY SSF101173 16 47 3.14E-5 T 29-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 SMALA_RS36700 b9dbc4f72fd4e2e273c6591e5b2d80db 2246 Gene3D G3DSA:3.40.47.10 39 308 1.8E-89 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS36700 b9dbc4f72fd4e2e273c6591e5b2d80db 2246 Gene3D G3DSA:3.40.366.10 576 716 9.0E-41 T 29-03-2018 SMALA_RS36700 b9dbc4f72fd4e2e273c6591e5b2d80db 2246 Gene3D G3DSA:3.30.70.250 717 761 7.1E-15 T 29-03-2018 SMALA_RS36700 b9dbc4f72fd4e2e273c6591e5b2d80db 2246 Pfam PF14765 Polyketide synthase dehydratase 952 1241 1.7E-51 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS36700 b9dbc4f72fd4e2e273c6591e5b2d80db 2246 Gene3D G3DSA:3.40.50.720 1606 1723 4.7E-25 T 29-03-2018 SMALA_RS36700 b9dbc4f72fd4e2e273c6591e5b2d80db 2246 SMART SM00826 952 1120 2.8E-83 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS36700 b9dbc4f72fd4e2e273c6591e5b2d80db 2246 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1797 1977 5.0E-46 T 29-03-2018 SMALA_RS36700 b9dbc4f72fd4e2e273c6591e5b2d80db 2246 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 304 421 6.9E-43 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS36700 b9dbc4f72fd4e2e273c6591e5b2d80db 2246 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 209 225 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS36700 b9dbc4f72fd4e2e273c6591e5b2d80db 2246 SMART SM01294 2084 2151 5.4E-5 T 29-03-2018 SMALA_RS36700 b9dbc4f72fd4e2e273c6591e5b2d80db 2246 Pfam PF08659 KR domain 1797 1975 8.0E-52 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS36700 b9dbc4f72fd4e2e273c6591e5b2d80db 2246 SUPERFAMILY SSF52151 578 705 1.41E-61 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS36700 b9dbc4f72fd4e2e273c6591e5b2d80db 2246 SUPERFAMILY SSF52151 772 876 1.41E-61 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS36700 b9dbc4f72fd4e2e273c6591e5b2d80db 2246 SUPERFAMILY SSF50129 1495 1613 3.46E-28 T 29-03-2018 IPR011032 GroES-like SMALA_RS36700 b9dbc4f72fd4e2e273c6591e5b2d80db 2246 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 47 296 5.6E-91 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS36700 b9dbc4f72fd4e2e273c6591e5b2d80db 2246 Gene3D G3DSA:3.40.47.10 311 472 1.5E-60 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS36700 b9dbc4f72fd4e2e273c6591e5b2d80db 2246 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2110 2125 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS36700 b9dbc4f72fd4e2e273c6591e5b2d80db 2246 Gene3D G3DSA:1.10.1200.10 2076 2180 8.2E-20 T 29-03-2018 SMALA_RS36700 b9dbc4f72fd4e2e273c6591e5b2d80db 2246 Gene3D G3DSA:3.40.366.10 762 884 2.4E-25 T 29-03-2018 SMALA_RS36700 b9dbc4f72fd4e2e273c6591e5b2d80db 2246 Gene3D G3DSA:3.90.180.10 1474 1605 2.3E-31 T 29-03-2018 SMALA_RS36700 b9dbc4f72fd4e2e273c6591e5b2d80db 2246 SUPERFAMILY SSF51735 1250 1457 1.85E-27 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS36700 b9dbc4f72fd4e2e273c6591e5b2d80db 2246 SUPERFAMILY SSF51735 1795 1997 3.94E-38 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS36700 b9dbc4f72fd4e2e273c6591e5b2d80db 2246 SUPERFAMILY SSF47336 2075 2163 1.24E-21 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS36700 b9dbc4f72fd4e2e273c6591e5b2d80db 2246 SMART SM00825 Beta-ketoacyl synthase 49 474 1.2E-222 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS36700 b9dbc4f72fd4e2e273c6591e5b2d80db 2246 SUPERFAMILY SSF53901 43 414 2.03E-102 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS36700 b9dbc4f72fd4e2e273c6591e5b2d80db 2246 Gene3D G3DSA:3.10.129.10 954 1074 7.6E-8 T 29-03-2018 SMALA_RS36700 b9dbc4f72fd4e2e273c6591e5b2d80db 2246 Pfam PF08990 Erythronolide synthase docking 15 40 7.1E-12 T 29-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 SMALA_RS36700 b9dbc4f72fd4e2e273c6591e5b2d80db 2246 SMART SM00823 Phosphopantetheine attachment site 2083 2155 2.0E-29 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS36700 b9dbc4f72fd4e2e273c6591e5b2d80db 2246 SUPERFAMILY SSF51735 1579 1716 2.6E-38 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS36700 b9dbc4f72fd4e2e273c6591e5b2d80db 2246 Pfam PF00550 Phosphopantetheine attachment site 2086 2150 8.1E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS36700 b9dbc4f72fd4e2e273c6591e5b2d80db 2246 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 580 883 6.3E-110 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS36700 b9dbc4f72fd4e2e273c6591e5b2d80db 2246 Gene3D G3DSA:3.40.50.720 1791 2040 5.7E-40 T 29-03-2018 SMALA_RS36700 b9dbc4f72fd4e2e273c6591e5b2d80db 2246 SUPERFAMILY SSF55048 703 771 7.19E-11 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS36700 b9dbc4f72fd4e2e273c6591e5b2d80db 2246 Pfam PF13602 Zinc-binding dehydrogenase 1654 1787 3.0E-19 T 29-03-2018 SMALA_RS31175 330a01cb27fa753176f66d0e288c08b9 777 SUPERFAMILY SSF53649 165 250 2.07E-10 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 SMALA_RS31175 330a01cb27fa753176f66d0e288c08b9 777 SUPERFAMILY SSF53649 306 448 2.07E-10 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 SMALA_RS31175 330a01cb27fa753176f66d0e288c08b9 777 Gene3D G3DSA:3.40.720.10 158 626 2.6E-15 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 SMALA_RS31175 330a01cb27fa753176f66d0e288c08b9 777 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 387 473 1.0E-7 T 29-03-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 SMALA_RS31175 330a01cb27fa753176f66d0e288c08b9 777 Pfam PF04020 Mycobacterial 4 TMS phage holin, superfamily IV 15 127 1.2E-11 T 29-03-2018 IPR007165 Mycobacterial 4 TMS phage holin, superfamily IV SMALA_RS06885 b607728a02a48b5f274a1ad1ceadf22e 2165 SMART SM00825 Beta-ketoacyl synthase 37 463 4.2E-191 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS06885 b607728a02a48b5f274a1ad1ceadf22e 2165 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 1541 1562 - T 29-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 SMALA_RS06885 b607728a02a48b5f274a1ad1ceadf22e 2165 Gene3D G3DSA:3.40.50.720 1724 1977 1.5E-44 T 29-03-2018 SMALA_RS06885 b607728a02a48b5f274a1ad1ceadf22e 2165 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 35 285 4.3E-78 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS06885 b607728a02a48b5f274a1ad1ceadf22e 2165 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 293 410 8.1E-41 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS06885 b607728a02a48b5f274a1ad1ceadf22e 2165 Gene3D G3DSA:3.40.47.10 27 297 1.8E-74 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS06885 b607728a02a48b5f274a1ad1ceadf22e 2165 Gene3D G3DSA:1.10.1200.10 1984 2092 8.0E-18 T 29-03-2018 SMALA_RS06885 b607728a02a48b5f274a1ad1ceadf22e 2165 SUPERFAMILY SSF51735 1512 1648 7.43E-37 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS06885 b607728a02a48b5f274a1ad1ceadf22e 2165 Gene3D G3DSA:3.40.366.10 567 709 1.5E-39 T 29-03-2018 SMALA_RS06885 b607728a02a48b5f274a1ad1ceadf22e 2165 SUPERFAMILY SSF50129 1427 1546 8.02E-27 T 29-03-2018 IPR011032 GroES-like SMALA_RS06885 b607728a02a48b5f274a1ad1ceadf22e 2165 SUPERFAMILY SSF55048 695 759 1.31E-11 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS06885 b607728a02a48b5f274a1ad1ceadf22e 2165 Pfam PF13602 Zinc-binding dehydrogenase 1592 1719 1.8E-18 T 29-03-2018 SMALA_RS06885 b607728a02a48b5f274a1ad1ceadf22e 2165 SUPERFAMILY SSF47336 2006 2092 1.3E-19 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS06885 b607728a02a48b5f274a1ad1ceadf22e 2165 Pfam PF00698 Acyl transferase domain 570 888 4.1E-72 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS06885 b607728a02a48b5f274a1ad1ceadf22e 2165 SMART SM00826 938 1107 5.6E-82 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS06885 b607728a02a48b5f274a1ad1ceadf22e 2165 Pfam PF14765 Polyketide synthase dehydratase 938 1218 5.2E-57 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS06885 b607728a02a48b5f274a1ad1ceadf22e 2165 SMART SM00823 Phosphopantetheine attachment site 2013 2085 2.3E-28 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS06885 b607728a02a48b5f274a1ad1ceadf22e 2165 SUPERFAMILY SSF53901 32 407 1.39E-97 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS06885 b607728a02a48b5f274a1ad1ceadf22e 2165 Gene3D G3DSA:3.40.47.10 300 461 3.7E-59 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS06885 b607728a02a48b5f274a1ad1ceadf22e 2165 SUPERFAMILY SSF52151 567 696 3.14E-59 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS06885 b607728a02a48b5f274a1ad1ceadf22e 2165 SUPERFAMILY SSF52151 761 859 3.14E-59 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS06885 b607728a02a48b5f274a1ad1ceadf22e 2165 SUPERFAMILY SSF51735 1729 1936 6.96E-44 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS06885 b607728a02a48b5f274a1ad1ceadf22e 2165 Pfam PF08659 KR domain 1729 1907 3.2E-57 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS06885 b607728a02a48b5f274a1ad1ceadf22e 2165 Gene3D G3DSA:3.30.70.250 710 753 3.4E-16 T 29-03-2018 SMALA_RS06885 b607728a02a48b5f274a1ad1ceadf22e 2165 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 413 530 5.1E-14 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS06885 b607728a02a48b5f274a1ad1ceadf22e 2165 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 1434 1489 1.1E-4 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS06885 b607728a02a48b5f274a1ad1ceadf22e 2165 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1729 1909 3.3E-57 T 29-03-2018 SMALA_RS06885 b607728a02a48b5f274a1ad1ceadf22e 2165 SMART SM01294 2015 2081 2.9E-5 T 29-03-2018 SMALA_RS06885 b607728a02a48b5f274a1ad1ceadf22e 2165 SUPERFAMILY SSF51735 1226 1391 1.3E-31 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS06885 b607728a02a48b5f274a1ad1ceadf22e 2165 Gene3D G3DSA:3.40.366.10 754 872 2.0E-21 T 29-03-2018 SMALA_RS06885 b607728a02a48b5f274a1ad1ceadf22e 2165 SMART SM00829 1414 1719 4.8E-176 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS06885 b607728a02a48b5f274a1ad1ceadf22e 2165 Pfam PF00550 Phosphopantetheine attachment site 2015 2081 1.1E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS06885 b607728a02a48b5f274a1ad1ceadf22e 2165 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2040 2055 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS06885 b607728a02a48b5f274a1ad1ceadf22e 2165 Gene3D G3DSA:3.90.180.10 1390 1722 7.0E-60 T 29-03-2018 SMALA_RS06885 b607728a02a48b5f274a1ad1ceadf22e 2165 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 571 870 5.4E-99 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS32100 8a72ddbcb9702544a590a9dfb2ab1ab5 489 PRINTS PR00757 Flavin-containing amine oxidase signature 15 34 1.0E-7 T 29-03-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 SMALA_RS32100 8a72ddbcb9702544a590a9dfb2ab1ab5 489 PRINTS PR00757 Flavin-containing amine oxidase signature 176 197 1.0E-7 T 29-03-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 SMALA_RS32100 8a72ddbcb9702544a590a9dfb2ab1ab5 489 PRINTS PR00757 Flavin-containing amine oxidase signature 447 464 1.0E-7 T 29-03-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 SMALA_RS32100 8a72ddbcb9702544a590a9dfb2ab1ab5 489 SUPERFAMILY SSF51905 14 332 5.76E-45 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS32100 8a72ddbcb9702544a590a9dfb2ab1ab5 489 SUPERFAMILY SSF51905 426 469 5.76E-45 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS32100 8a72ddbcb9702544a590a9dfb2ab1ab5 489 Gene3D G3DSA:3.40.50.720 4 155 1.5E-11 T 29-03-2018 SMALA_RS32100 8a72ddbcb9702544a590a9dfb2ab1ab5 489 Gene3D G3DSA:3.50.50.60 164 472 3.5E-17 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS32100 8a72ddbcb9702544a590a9dfb2ab1ab5 489 TIGRFAM TIGR03467 HpnE: squalene-associated FAD-dependent desaturase 17 466 8.1E-128 T 29-03-2018 IPR017830 Squalene-associated FAD-dependent desaturase SMALA_RS32100 8a72ddbcb9702544a590a9dfb2ab1ab5 489 Pfam PF01593 Flavin containing amine oxidoreductase 23 464 4.8E-39 T 29-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 SMALA_RS38400 da2f5189eb2ef96da7a8bc12b7f4392a 781 SUPERFAMILY SSF74650 5 270 2.64E-65 T 29-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 SMALA_RS38400 da2f5189eb2ef96da7a8bc12b7f4392a 781 PIRSF PIRSF036289 2 762 1.6E-216 T 29-03-2018 IPR017045 Maltose phosphorylase/glycosyl hydrolase/vacuolar acid trehalase SMALA_RS38400 da2f5189eb2ef96da7a8bc12b7f4392a 781 Pfam PF03633 Glycosyl hydrolase family 65, C-terminal domain 700 750 8.2E-14 T 29-03-2018 IPR005194 Glycoside hydrolase family 65, C-terminal SMALA_RS38400 da2f5189eb2ef96da7a8bc12b7f4392a 781 SUPERFAMILY SSF48208 279 748 3.78E-118 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 SMALA_RS38400 da2f5189eb2ef96da7a8bc12b7f4392a 781 Gene3D G3DSA:2.60.420.10 682 753 2.5E-22 T 29-03-2018 SMALA_RS38400 da2f5189eb2ef96da7a8bc12b7f4392a 781 Gene3D G3DSA:2.70.98.40 3 273 5.7E-76 T 29-03-2018 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 SMALA_RS38400 da2f5189eb2ef96da7a8bc12b7f4392a 781 Pfam PF03632 Glycosyl hydrolase family 65 central catalytic domain 327 695 1.5E-138 T 29-03-2018 IPR005195 Glycoside hydrolase, family 65, central catalytic GO:0003824|GO:0005975 SMALA_RS38400 da2f5189eb2ef96da7a8bc12b7f4392a 781 Pfam PF03636 Glycosyl hydrolase family 65, N-terminal domain 16 270 2.0E-58 T 29-03-2018 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 SMALA_RS38400 da2f5189eb2ef96da7a8bc12b7f4392a 781 Gene3D G3DSA:1.50.10.10 321 681 3.7E-109 T 29-03-2018 SMALA_RS11755 ac7cc54fdb1c77dd2838982a7686b54c 190 Gene3D G3DSA:1.10.10.60 7 52 1.7E-16 T 29-03-2018 SMALA_RS11755 ac7cc54fdb1c77dd2838982a7686b54c 190 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 57 4.1E-15 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS11755 ac7cc54fdb1c77dd2838982a7686b54c 190 Gene3D G3DSA:1.10.357.10 53 183 1.1E-16 T 29-03-2018 SMALA_RS11755 ac7cc54fdb1c77dd2838982a7686b54c 190 SUPERFAMILY SSF46689 8 63 8.03E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS11755 ac7cc54fdb1c77dd2838982a7686b54c 190 ProSitePatterns PS01081 TetR-type HTH domain signature. 24 55 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site SMALA_RS11755 ac7cc54fdb1c77dd2838982a7686b54c 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 1.7E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS11755 ac7cc54fdb1c77dd2838982a7686b54c 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 1.7E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS30490 bfbacdd52d4d0cbe7386536aa2424c75 577 Pfam PF13193 AMP-binding enzyme C-terminal domain 478 555 1.4E-17 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS30490 bfbacdd52d4d0cbe7386536aa2424c75 577 Pfam PF00501 AMP-binding enzyme 47 469 1.0E-71 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS30490 bfbacdd52d4d0cbe7386536aa2424c75 577 Gene3D G3DSA:3.40.50.980 35 223 5.5E-31 T 29-03-2018 SMALA_RS30490 bfbacdd52d4d0cbe7386536aa2424c75 577 SUPERFAMILY SSF56801 15 566 2.35E-128 T 29-03-2018 SMALA_RS30490 bfbacdd52d4d0cbe7386536aa2424c75 577 Gene3D G3DSA:2.30.38.10 372 462 1.5E-20 T 29-03-2018 SMALA_RS30490 bfbacdd52d4d0cbe7386536aa2424c75 577 Gene3D G3DSA:3.30.300.30 465 572 1.0E-20 T 29-03-2018 SMALA_RS30490 bfbacdd52d4d0cbe7386536aa2424c75 577 Gene3D G3DSA:3.40.50.980 224 371 2.2E-32 T 29-03-2018 SMALA_RS37000 a4036c807715b2af2901846f24fa9be5 174 Gene3D G3DSA:2.60.120.260 30 172 7.2E-15 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS37000 a4036c807715b2af2901846f24fa9be5 174 SUPERFAMILY SSF49785 39 172 6.38E-9 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS29210 3900015125af6340bb9c0ab57f87acad 193 Gene3D G3DSA:3.10.129.10 17 166 5.6E-27 T 29-03-2018 SMALA_RS29210 3900015125af6340bb9c0ab57f87acad 193 Pfam PF03061 Thioesterase superfamily 74 140 4.4E-8 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 SMALA_RS29210 3900015125af6340bb9c0ab57f87acad 193 SUPERFAMILY SSF54637 22 158 5.04E-29 T 29-03-2018 IPR029069 HotDog domain SMALA_RS05385 3929724849f86963f0d7951ca498a7c2 222 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 76 183 8.4E-17 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMALA_RS05385 3929724849f86963f0d7951ca498a7c2 222 SUPERFAMILY SSF56784 1 213 1.13E-46 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS05385 3929724849f86963f0d7951ca498a7c2 222 Gene3D G3DSA:3.40.50.1000 1 27 0.018 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS05385 3929724849f86963f0d7951ca498a7c2 222 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 184 5.4E-24 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS05385 3929724849f86963f0d7951ca498a7c2 222 Gene3D G3DSA:3.40.50.1000 74 221 1.4E-28 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS05385 3929724849f86963f0d7951ca498a7c2 222 Gene3D G3DSA:1.10.150.240 28 73 2.3E-11 T 29-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 SMALA_RS05385 3929724849f86963f0d7951ca498a7c2 222 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 146 166 1.6E-7 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMALA_RS05385 3929724849f86963f0d7951ca498a7c2 222 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 128 144 1.6E-7 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMALA_RS05385 3929724849f86963f0d7951ca498a7c2 222 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 173 186 1.6E-7 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMALA_RS05385 3929724849f86963f0d7951ca498a7c2 222 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 2 13 1.6E-7 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMALA_RS33255 8daf88a7ebc1ef25c0b24e62cc422a12 294 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 187 8.0E-23 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 SMALA_RS33255 8daf88a7ebc1ef25c0b24e62cc422a12 294 SUPERFAMILY SSF51735 2 283 5.27E-50 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS33255 8daf88a7ebc1ef25c0b24e62cc422a12 294 Gene3D G3DSA:3.40.50.720 2 291 8.2E-39 T 29-03-2018 SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 5745 5902 4.7E-32 T 29-03-2018 IPR010060 Non-ribosomal peptide synthase SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1803 1814 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 SUPERFAMILY SSF56801 573 1121 7.72E-140 T 29-03-2018 SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 Gene3D G3DSA:3.30.300.30 3095 3210 4.9E-34 T 29-03-2018 SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 Gene3D G3DSA:3.30.300.30 996 1111 3.2E-37 T 29-03-2018 SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 Gene3D G3DSA:3.30.300.30 5229 5344 9.1E-37 T 29-03-2018 SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 Gene3D G3DSA:3.30.300.30 4144 4259 3.7E-34 T 29-03-2018 SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 Gene3D G3DSA:3.30.300.30 2045 2160 1.1E-35 T 29-03-2018 SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 Gene3D G3DSA:3.30.559.10 5417 5619 4.7E-17 T 29-03-2018 SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 SUPERFAMILY SSF56801 4782 5352 2.62E-151 T 29-03-2018 SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 SUPERFAMILY SSF52777 5612 5878 1.45E-29 T 29-03-2018 SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 ProSitePatterns PS00455 Putative AMP-binding domain signature. 757 768 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 Gene3D G3DSA:3.40.50.980 1806 1951 8.9E-32 T 29-03-2018 SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 SUPERFAMILY SSF52777 5421 5625 2.89E-24 T 29-03-2018 SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 SUPERFAMILY SSF56801 2674 3220 7.33E-138 T 29-03-2018 SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 SUPERFAMILY SSF47336 3201 3272 4.58E-19 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 SUPERFAMILY SSF52777 2428 2701 1.05E-60 T 29-03-2018 SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 ProSitePatterns PS00455 Putative AMP-binding domain signature. 3902 3913 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 SUPERFAMILY SSF52777 4528 4808 9.12E-60 T 29-03-2018 SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 Gene3D G3DSA:3.30.559.10 3267 3492 9.2E-47 T 29-03-2018 SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 Gene3D G3DSA:3.30.559.10 1175 1395 1.4E-45 T 29-03-2018 SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 Gene3D G3DSA:3.30.559.10 2225 2447 1.4E-46 T 29-03-2018 SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 Gene3D G3DSA:3.30.559.10 4324 4545 1.9E-48 T 29-03-2018 SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 SUPERFAMILY SSF56801 1621 2170 8.77E-141 T 29-03-2018 SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 Pfam PF00550 Phosphopantetheine attachment site 3210 3268 1.6E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 Pfam PF00550 Phosphopantetheine attachment site 4259 4317 3.3E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 Pfam PF00550 Phosphopantetheine attachment site 5342 5400 3.7E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 Pfam PF00550 Phosphopantetheine attachment site 1111 1169 5.3E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 Pfam PF00550 Phosphopantetheine attachment site 2160 2218 5.3E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 Gene3D G3DSA:3.40.50.980 4813 4981 6.8E-46 T 29-03-2018 SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 Gene3D G3DSA:3.40.50.980 1653 1805 9.0E-40 T 29-03-2018 SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 Gene3D G3DSA:3.40.50.980 3751 3904 6.7E-43 T 29-03-2018 SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 SUPERFAMILY SSF47336 5333 5401 6.81E-16 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 SUPERFAMILY SSF52777 2244 2415 2.78E-48 T 29-03-2018 SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 Gene3D G3DSA:1.10.1200.10 2161 2224 2.1E-21 T 29-03-2018 SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 Gene3D G3DSA:1.10.1200.10 4260 4323 1.4E-21 T 29-03-2018 SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 Gene3D G3DSA:1.10.1200.10 1112 1174 1.9E-21 T 29-03-2018 SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 Gene3D G3DSA:1.10.1200.10 3211 3266 3.6E-22 T 29-03-2018 SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2856 2867 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 SUPERFAMILY SSF52777 1195 1368 3.22E-51 T 29-03-2018 SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 4841 5257 3.3E-128 T 29-03-2018 IPR010071 Amino acid adenylation domain SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1681 2073 2.0E-119 T 29-03-2018 IPR010071 Amino acid adenylation domain SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 634 1025 1.4E-119 T 29-03-2018 IPR010071 Amino acid adenylation domain SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 3779 4172 3.9E-119 T 29-03-2018 IPR010071 Amino acid adenylation domain SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2734 3123 4.8E-119 T 29-03-2018 IPR010071 Amino acid adenylation domain SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 Gene3D G3DSA:3.40.50.980 606 751 2.0E-32 T 29-03-2018 SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4280 4295 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 Gene3D G3DSA:3.30.559.10 134 351 3.6E-38 T 29-03-2018 SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 SUPERFAMILY SSF56801 3719 4269 6.93E-143 T 29-03-2018 SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 SMART SM00823 Phosphopantetheine attachment site 2157 2226 8.6E-4 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 SMART SM00823 Phosphopantetheine attachment site 4256 4325 5.9E-4 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 SMART SM00823 Phosphopantetheine attachment site 1108 1177 8.6E-4 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 SMART SM00823 Phosphopantetheine attachment site 3207 3276 3.2E-4 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 SMART SM00823 Phosphopantetheine attachment site 5339 5407 5.5E-7 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 SUPERFAMILY SSF47336 4250 4321 5.1E-19 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 Gene3D G3DSA:3.40.50.980 2706 2860 1.7E-41 T 29-03-2018 SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 SUPERFAMILY SSF47336 2151 2222 9.55E-19 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 SUPERFAMILY SSF47336 1102 1173 9.55E-19 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3231 3246 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1132 1147 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 Gene3D G3DSA:2.30.38.10 915 994 1.1E-21 T 29-03-2018 SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 Gene3D G3DSA:2.30.38.10 4063 4142 2.4E-23 T 29-03-2018 SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 Gene3D G3DSA:2.30.38.10 3010 3093 1.1E-21 T 29-03-2018 SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 Gene3D G3DSA:2.30.38.10 1960 2043 2.4E-23 T 29-03-2018 SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 Gene3D G3DSA:3.40.50.980 752 914 2.7E-27 T 29-03-2018 SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 Gene3D G3DSA:3.40.50.980 3905 4062 2.8E-35 T 29-03-2018 SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 Gene3D G3DSA:1.10.1200.10 5345 5416 3.2E-21 T 29-03-2018 SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 SUPERFAMILY SSF52777 157 340 1.45E-39 T 29-03-2018 SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 Pfam PF13193 AMP-binding enzyme C-terminal domain 1009 1084 1.1E-12 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 Pfam PF13193 AMP-binding enzyme C-terminal domain 5242 5317 1.1E-12 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 Pfam PF13193 AMP-binding enzyme C-terminal domain 4157 4232 5.0E-9 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 Pfam PF13193 AMP-binding enzyme C-terminal domain 3108 3183 7.4E-9 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 Pfam PF13193 AMP-binding enzyme C-terminal domain 2058 2133 2.7E-11 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 SUPERFAMILY SSF52777 1381 1648 5.89E-62 T 29-03-2018 SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 Gene3D G3DSA:3.40.50.980 4982 5134 1.2E-31 T 29-03-2018 SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 Pfam PF00668 Condensation domain 5442 5881 2.5E-30 T 29-03-2018 IPR001242 Condensation domain SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 Pfam PF00668 Condensation domain 1193 1634 2.0E-89 T 29-03-2018 IPR001242 Condensation domain SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 Pfam PF00668 Condensation domain 2242 2687 4.2E-92 T 29-03-2018 IPR001242 Condensation domain SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 Pfam PF00668 Condensation domain 4341 4798 1.1E-94 T 29-03-2018 IPR001242 Condensation domain SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 Pfam PF00668 Condensation domain 159 584 3.0E-78 T 29-03-2018 IPR001242 Condensation domain SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 Pfam PF00668 Condensation domain 3292 3732 3.6E-91 T 29-03-2018 IPR001242 Condensation domain SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2181 2196 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 SUPERFAMILY SSF52777 4343 4515 4.34E-53 T 29-03-2018 SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 Pfam PF00501 AMP-binding enzyme 4822 5233 1.0E-93 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 Pfam PF00501 AMP-binding enzyme 2713 3100 2.2E-79 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 Pfam PF00501 AMP-binding enzyme 3758 4149 4.2E-88 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 Pfam PF00501 AMP-binding enzyme 613 1001 2.4E-79 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 Pfam PF00501 AMP-binding enzyme 1660 2050 2.7E-87 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 SUPERFAMILY SSF52777 3294 3465 5.34E-51 T 29-03-2018 SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 Gene3D G3DSA:2.30.38.10 5143 5224 5.5E-22 T 29-03-2018 SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 SUPERFAMILY SSF52777 3478 3746 4.0E-59 T 29-03-2018 SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 SUPERFAMILY SSF52777 342 601 1.22E-55 T 29-03-2018 SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 ProSitePatterns PS00455 Putative AMP-binding domain signature. 4977 4988 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS33505 5ae957d9b53867e942613514fb233fbd 5909 Gene3D G3DSA:3.40.50.980 2861 2997 6.9E-23 T 29-03-2018 SMALA_RS28640 68a74aa0132cf801752b172f3b028456 95 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 6 89 2.2E-38 T 29-03-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS28640 68a74aa0132cf801752b172f3b028456 95 Pfam PF00312 Ribosomal protein S15 8 88 2.6E-37 T 29-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS28640 68a74aa0132cf801752b172f3b028456 95 SUPERFAMILY SSF47060 3 89 2.09E-35 T 29-03-2018 IPR009068 S15/NS1, RNA-binding SMALA_RS28640 68a74aa0132cf801752b172f3b028456 95 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 22.443 T 29-03-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS28640 68a74aa0132cf801752b172f3b028456 95 SMART SM01387 8 88 1.5E-52 T 29-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS28640 68a74aa0132cf801752b172f3b028456 95 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 29-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS28640 68a74aa0132cf801752b172f3b028456 95 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 11 88 2.0E-24 T 29-03-2018 SMALA_RS28640 68a74aa0132cf801752b172f3b028456 95 Gene3D G3DSA:1.10.287.10 2 89 2.8E-35 T 29-03-2018 SMALA_RS23465 02452edc5710376d875904ad955b60e5 338 Gene3D G3DSA:3.40.50.2300 63 182 1.5E-30 T 29-03-2018 SMALA_RS23465 02452edc5710376d875904ad955b60e5 338 Gene3D G3DSA:1.10.260.40 25 62 8.9E-23 T 29-03-2018 SMALA_RS23465 02452edc5710376d875904ad955b60e5 338 Pfam PF13377 Periplasmic binding protein-like domain 177 333 6.3E-27 T 29-03-2018 SMALA_RS23465 02452edc5710376d875904ad955b60e5 338 SMART SM00354 10 81 7.1E-25 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS23465 02452edc5710376d875904ad955b60e5 338 Gene3D G3DSA:1.10.10.10 3 24 1.2E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS23465 02452edc5710376d875904ad955b60e5 338 SUPERFAMILY SSF53822 69 324 7.66E-59 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SMALA_RS23465 02452edc5710376d875904ad955b60e5 338 Pfam PF00356 Bacterial regulatory proteins, lacI family 12 57 1.2E-13 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS23465 02452edc5710376d875904ad955b60e5 338 SUPERFAMILY SSF47413 11 66 1.18E-15 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS23465 02452edc5710376d875904ad955b60e5 338 Gene3D G3DSA:3.40.50.2300 183 313 4.3E-35 T 29-03-2018 SMALA_RS06125 5521244a2003866f4aa3654afaf7a8b2 700 Gene3D G3DSA:3.30.420.40 2 330 1.7E-11 T 29-03-2018 SMALA_RS06125 5521244a2003866f4aa3654afaf7a8b2 700 Pfam PF01968 Hydantoinase/oxoprolinase 214 501 4.1E-75 T 29-03-2018 IPR002821 Hydantoinase/oxoprolinase GO:0016787 Reactome: R-HSA-174403 SMALA_RS06125 5521244a2003866f4aa3654afaf7a8b2 700 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 5 193 1.6E-44 T 29-03-2018 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403 SMALA_RS06125 5521244a2003866f4aa3654afaf7a8b2 700 SUPERFAMILY SSF53067 1 53 9.72E-6 T 29-03-2018 SMALA_RS39090 ff85869071a91f6a32c1f3dbb999f995 796 SUPERFAMILY SSF46894 691 755 2.21E-18 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS39090 ff85869071a91f6a32c1f3dbb999f995 796 Gene3D G3DSA:1.25.40.10 577 682 0.0019 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS39090 ff85869071a91f6a32c1f3dbb999f995 796 SUPERFAMILY SSF48452 485 621 5.48E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS39090 ff85869071a91f6a32c1f3dbb999f995 796 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 712 728 9.3E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS39090 ff85869071a91f6a32c1f3dbb999f995 796 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 728 740 9.3E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS39090 ff85869071a91f6a32c1f3dbb999f995 796 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 698 712 9.3E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS39090 ff85869071a91f6a32c1f3dbb999f995 796 Pfam PF13401 AAA domain 40 124 6.7E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS39090 ff85869071a91f6a32c1f3dbb999f995 796 SMART SM00382 39 163 0.0026 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS39090 ff85869071a91f6a32c1f3dbb999f995 796 Gene3D G3DSA:3.40.50.300 4 146 1.7E-15 T 29-03-2018 SMALA_RS39090 ff85869071a91f6a32c1f3dbb999f995 796 Pfam PF00196 Bacterial regulatory proteins, luxR family 697 751 4.0E-16 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS39090 ff85869071a91f6a32c1f3dbb999f995 796 SMART SM00421 695 752 7.7E-23 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS39090 ff85869071a91f6a32c1f3dbb999f995 796 Gene3D G3DSA:1.25.40.10 379 576 1.2E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS39090 ff85869071a91f6a32c1f3dbb999f995 796 SUPERFAMILY SSF52540 11 277 2.03E-17 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS39090 ff85869071a91f6a32c1f3dbb999f995 796 Gene3D G3DSA:1.10.10.10 688 763 5.5E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS37860 ab033ce6b45158ad750afba23b483c7d 478 Gene3D G3DSA:3.40.50.980 143 290 3.3E-31 T 29-03-2018 SMALA_RS37860 ab033ce6b45158ad750afba23b483c7d 478 Gene3D G3DSA:2.30.38.10 291 373 6.4E-15 T 29-03-2018 SMALA_RS37860 ab033ce6b45158ad750afba23b483c7d 478 Pfam PF00501 AMP-binding enzyme 12 374 7.9E-60 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS37860 ab033ce6b45158ad750afba23b483c7d 478 Gene3D G3DSA:3.40.50.980 4 142 9.9E-21 T 29-03-2018 SMALA_RS37860 ab033ce6b45158ad750afba23b483c7d 478 SUPERFAMILY SSF56801 11 472 2.35E-87 T 29-03-2018 SMALA_RS37860 ab033ce6b45158ad750afba23b483c7d 478 ProSitePatterns PS00455 Putative AMP-binding domain signature. 135 146 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS37860 ab033ce6b45158ad750afba23b483c7d 478 Gene3D G3DSA:3.30.300.30 380 472 2.4E-14 T 29-03-2018 SMALA_RS36070 82a28249b4b94858a5c7ef0605d14236 355 Gene3D G3DSA:3.20.20.190 38 332 2.0E-13 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 SMALA_RS36070 82a28249b4b94858a5c7ef0605d14236 355 Pfam PF16670 Phosphoinositide phospholipase C, Ca2+-dependent 112 211 2.7E-13 T 29-03-2018 IPR032075 Phosphoinositide phospholipase C, Ca2+-dependent SMALA_RS36070 82a28249b4b94858a5c7ef0605d14236 355 SUPERFAMILY SSF51695 41 231 1.46E-11 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 SMALA_RS35310 6ab1102e6867876b7d62315db7608ea1 127 ProSitePatterns PS00234 Gas vesicles protein GVPa signature 1. 30 44 - T 29-03-2018 IPR018493 Gas vesicle protein GvpA, conserved site GO:0005198|GO:0012506 SMALA_RS35310 6ab1102e6867876b7d62315db7608ea1 127 Pfam PF00741 Gas vesicle protein 29 67 9.1E-17 T 29-03-2018 IPR000638 Gas vesicle protein GvpA GO:0005198|GO:0012506 SMALA_RS39105 98be57c3eede85de9089210006ffcd00 401 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 340 349 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMALA_RS39105 98be57c3eede85de9089210006ffcd00 401 Gene3D G3DSA:1.10.630.10 7 401 3.2E-73 T 29-03-2018 SMALA_RS39105 98be57c3eede85de9089210006ffcd00 401 Pfam PF00067 Cytochrome P450 211 368 5.1E-25 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS39105 98be57c3eede85de9089210006ffcd00 401 PRINTS PR00385 P450 superfamily signature 338 347 1.2E-7 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS39105 98be57c3eede85de9089210006ffcd00 401 PRINTS PR00385 P450 superfamily signature 347 358 1.2E-7 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS39105 98be57c3eede85de9089210006ffcd00 401 PRINTS PR00385 P450 superfamily signature 237 254 1.2E-7 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS39105 98be57c3eede85de9089210006ffcd00 401 PRINTS PR00385 P450 superfamily signature 272 283 1.2E-7 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS39105 98be57c3eede85de9089210006ffcd00 401 PRINTS PR00359 B-class P450 signature 272 283 6.0E-55 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS39105 98be57c3eede85de9089210006ffcd00 401 PRINTS PR00359 B-class P450 signature 159 174 6.0E-55 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS39105 98be57c3eede85de9089210006ffcd00 401 PRINTS PR00359 B-class P450 signature 142 158 6.0E-55 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS39105 98be57c3eede85de9089210006ffcd00 401 PRINTS PR00359 B-class P450 signature 347 358 6.0E-55 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS39105 98be57c3eede85de9089210006ffcd00 401 PRINTS PR00359 B-class P450 signature 196 218 6.0E-55 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS39105 98be57c3eede85de9089210006ffcd00 401 PRINTS PR00359 B-class P450 signature 289 316 6.0E-55 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS39105 98be57c3eede85de9089210006ffcd00 401 PRINTS PR00359 B-class P450 signature 317 332 6.0E-55 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS39105 98be57c3eede85de9089210006ffcd00 401 PRINTS PR00359 B-class P450 signature 338 347 6.0E-55 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS39105 98be57c3eede85de9089210006ffcd00 401 PRINTS PR00359 B-class P450 signature 95 106 6.0E-55 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS39105 98be57c3eede85de9089210006ffcd00 401 SUPERFAMILY SSF48264 18 399 1.57E-91 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS07245 7856da2934ccfe0afc65be8713bafa30 260 SUPERFAMILY SSF56235 10 227 2.04E-44 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SMALA_RS07245 7856da2934ccfe0afc65be8713bafa30 260 TIGRFAM TIGR03691 20S_bact_alpha: proteasome, alpha subunit 2 230 2.9E-117 T 29-03-2018 IPR022296 Proteasome, alpha subunit, bacterial GO:0004298|GO:0019773|GO:0051603 SMALA_RS07245 7856da2934ccfe0afc65be8713bafa30 260 Pfam PF00227 Proteasome subunit 25 207 8.1E-29 T 29-03-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-446652|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8941858|Reactome: R-HSA-8951664|Reactome: R-HSA-983168 SMALA_RS07245 7856da2934ccfe0afc65be8713bafa30 260 Hamap MF_00289_B Proteasome subunit alpha [prcA]. 1 234 49.513 T 29-03-2018 IPR022296 Proteasome, alpha subunit, bacterial GO:0004298|GO:0019773|GO:0051603 SMALA_RS07245 7856da2934ccfe0afc65be8713bafa30 260 Gene3D G3DSA:3.60.20.10 7 234 1.2E-45 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 Gene3D G3DSA:3.40.50.720 6426 6671 1.3E-49 T 29-03-2018 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 Gene3D G3DSA:3.40.50.720 2815 3064 1.2E-42 T 29-03-2018 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 Gene3D G3DSA:3.40.50.720 4869 5111 2.5E-39 T 29-03-2018 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 Pfam PF00501 AMP-binding enzyme 15 417 3.4E-103 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 SMART SM01294 1048 1115 8.2E-5 T 29-03-2018 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 SMART SM01294 5162 5229 8.2E-7 T 29-03-2018 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 SMART SM01294 6704 6770 1.4E-4 T 29-03-2018 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 SMART SM01294 3105 3172 7.2E-4 T 29-03-2018 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 SUPERFAMILY SSF51735 2818 3017 3.11E-41 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 SUPERFAMILY SSF52151 3932 4025 8.11E-62 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 SUPERFAMILY SSF52151 3737 3866 8.11E-62 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 SUPERFAMILY SSF51735 4664 4836 2.56E-30 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 Gene3D G3DSA:3.30.300.30 412 520 8.5E-25 T 29-03-2018 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 SUPERFAMILY SSF53901 5253 5627 3.61E-103 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 5419 5435 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 SUPERFAMILY SSF51735 6199 6408 1.1E-38 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 SUPERFAMILY SSF51735 6418 6649 2.39E-47 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 Gene3D G3DSA:1.10.1200.10 6682 6775 4.2E-19 T 29-03-2018 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 Gene3D G3DSA:3.40.50.980 177 327 9.5E-41 T 29-03-2018 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 Pfam PF00698 Acyl transferase domain 3739 4059 2.8E-78 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 Pfam PF00698 Acyl transferase domain 5794 6113 1.3E-85 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 Pfam PF00698 Acyl transferase domain 1675 1992 1.8E-78 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 SUPERFAMILY SSF53901 3192 3568 1.13E-100 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 Pfam PF08659 KR domain 4875 5054 3.7E-57 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 Pfam PF08659 KR domain 793 956 6.4E-18 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 Pfam PF08659 KR domain 6420 6597 7.9E-55 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 Pfam PF08659 KR domain 2822 3001 1.4E-57 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 2531 2587 5.5E-5 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 4587 4640 1.7E-4 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 SMART SM00825 Beta-ketoacyl synthase 3198 3624 3.2E-220 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 SMART SM00825 Beta-ketoacyl synthase 5258 5684 1.5E-219 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 SMART SM00825 Beta-ketoacyl synthase 1139 1565 2.6E-220 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 3574 3699 5.1E-15 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 5634 5757 2.9E-12 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1515 1638 1.1E-11 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 SUPERFAMILY SSF51735 2323 2493 8.66E-30 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 Gene3D G3DSA:3.90.180.10 6225 6425 0.011 T 29-03-2018 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 Gene3D G3DSA:3.30.70.250 1809 1858 6.2E-13 T 29-03-2018 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 SUPERFAMILY SSF50129 2508 2648 6.45E-26 T 29-03-2018 IPR011032 GroES-like SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 Pfam PF13193 AMP-binding enzyme C-terminal domain 426 500 3.2E-18 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 SUPERFAMILY SSF56801 8 510 1.27E-150 T 29-03-2018 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 Pfam PF14765 Polyketide synthase dehydratase 4108 4381 4.1E-53 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 Pfam PF14765 Polyketide synthase dehydratase 2041 2312 3.4E-60 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3131 3146 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 Gene3D G3DSA:3.40.366.10 5981 6099 5.0E-26 T 29-03-2018 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 Gene3D G3DSA:3.40.366.10 5792 5930 6.5E-43 T 29-03-2018 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 Gene3D G3DSA:3.40.366.10 3885 4038 1.5E-29 T 29-03-2018 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 Gene3D G3DSA:3.30.70.250 5931 5980 1.7E-16 T 29-03-2018 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 5514 5631 8.8E-45 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 3454 3571 6.5E-44 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1395 1512 5.3E-44 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 SUPERFAMILY SSF50129 4562 4701 5.03E-27 T 29-03-2018 IPR011032 GroES-like SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 SUPERFAMILY SSF55048 5920 5985 1.7E-12 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 Gene3D G3DSA:3.40.366.10 3734 3884 4.5E-42 T 29-03-2018 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 Gene3D G3DSA:3.40.366.10 1670 1808 1.1E-43 T 29-03-2018 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 Gene3D G3DSA:3.40.47.10 3461 3622 1.4E-63 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 Gene3D G3DSA:3.40.47.10 5521 5682 3.7E-64 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 Gene3D G3DSA:3.40.47.10 1402 1563 2.3E-62 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 Gene3D G3DSA:3.40.50.980 7 176 8.4E-39 T 29-03-2018 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 Pfam PF13602 Zinc-binding dehydrogenase 4754 4865 6.7E-14 T 29-03-2018 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 Pfam PF13602 Zinc-binding dehydrogenase 2693 2812 8.9E-15 T 29-03-2018 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 ProSitePatterns PS00012 Phosphopantetheine attachment site. 6729 6744 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 SUPERFAMILY SSF51735 792 965 2.08E-20 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 SUPERFAMILY SSF55048 1801 1864 5.49E-10 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 SUPERFAMILY SSF52151 5792 5921 3.14E-69 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 SUPERFAMILY SSF52151 5986 6082 3.14E-69 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 SMART SM00829 4567 4865 4.0E-169 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 SMART SM00829 2512 2812 6.4E-173 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 Gene3D G3DSA:1.10.1200.10 5156 5257 1.5E-19 T 29-03-2018 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 Gene3D G3DSA:1.10.1200.10 3097 3197 5.4E-22 T 29-03-2018 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 SUPERFAMILY SSF53901 1135 1502 1.01E-103 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 SUPERFAMILY SSF51735 4390 4548 4.72E-29 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1300 1316 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 Gene3D G3DSA:3.10.129.10 2043 2166 1.6E-7 T 29-03-2018 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 Gene3D G3DSA:3.10.129.10 4108 4226 1.6E-5 T 29-03-2018 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 SUPERFAMILY SSF47336 5158 5270 2.88E-21 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 3359 3375 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 SUPERFAMILY SSF51735 4874 5105 1.13E-39 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 Pfam PF00550 Phosphopantetheine attachment site 3107 3171 3.7E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 Pfam PF00550 Phosphopantetheine attachment site 6706 6770 7.3E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 Pfam PF00550 Phosphopantetheine attachment site 5163 5228 1.6E-8 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 Pfam PF00550 Phosphopantetheine attachment site 1050 1115 3.4E-9 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6419 6599 2.2E-45 T 29-03-2018 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4875 5055 3.2E-58 T 29-03-2018 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 793 960 2.3E-9 T 29-03-2018 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2822 3002 2.2E-57 T 29-03-2018 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 5796 6095 9.7E-121 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1677 1974 8.5E-115 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 3741 4041 2.2E-107 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 Gene3D G3DSA:3.90.180.10 4556 4868 1.2E-56 T 29-03-2018 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 Gene3D G3DSA:3.90.180.10 2392 2814 1.4E-56 T 29-03-2018 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 SMART SM00823 Phosphopantetheine attachment site 6703 6774 1.5E-29 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 SMART SM00823 Phosphopantetheine attachment site 3104 3176 2.3E-30 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 SMART SM00823 Phosphopantetheine attachment site 1047 1119 5.1E-28 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 SMART SM00823 Phosphopantetheine attachment site 5161 5233 1.6E-29 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 Gene3D G3DSA:3.40.50.720 784 1137 1.7E-38 T 29-03-2018 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 SUPERFAMILY SSF51735 2611 2783 4.36E-31 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 SUPERFAMILY SSF47336 3099 3211 2.62E-23 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 SUPERFAMILY SSF47336 6696 6778 2.62E-19 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 ProSitePatterns PS00012 Phosphopantetheine attachment site. 5188 5203 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 SMART SM00826 4108 4269 7.1E-76 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 SMART SM00826 2041 2201 1.6E-76 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1137 1387 3.1E-88 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3196 3446 3.1E-87 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 5256 5506 6.8E-87 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 SUPERFAMILY SSF51735 629 779 1.44E-13 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 SUPERFAMILY SSF51735 522 572 1.44E-13 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 Gene3D G3DSA:2.30.38.10 328 410 6.0E-28 T 29-03-2018 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 SUPERFAMILY SSF55048 3865 3925 1.83E-8 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 Gene3D G3DSA:3.40.366.10 1859 1975 1.0E-25 T 29-03-2018 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 SUPERFAMILY SSF52151 1865 1961 9.16E-68 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 SUPERFAMILY SSF52151 1673 1802 9.16E-68 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 ProSitePatterns PS00455 Putative AMP-binding domain signature. 170 181 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 Gene3D G3DSA:3.40.47.10 5258 5518 1.7E-79 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 Gene3D G3DSA:3.40.47.10 3198 3458 1.1E-82 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 Gene3D G3DSA:3.40.47.10 1138 1399 5.8E-84 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 SUPERFAMILY SSF47336 1044 1151 1.7E-18 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS04340 1581ad1cd1cc7ba4376655fb1baa3445 6856 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 2639 2660 - T 29-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 SMALA_RS33480 15e17377d28fb3146e33979fad394235 326 SUPERFAMILY SSF46785 227 298 1.72E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS33480 15e17377d28fb3146e33979fad394235 326 Pfam PF12840 Helix-turn-helix domain 228 284 4.4E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS33480 15e17377d28fb3146e33979fad394235 326 SMART SM00418 228 303 3.2E-8 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS33480 15e17377d28fb3146e33979fad394235 326 Gene3D G3DSA:1.10.10.10 212 303 1.1E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS33480 15e17377d28fb3146e33979fad394235 326 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 261 276 1.4E-5 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS33480 15e17377d28fb3146e33979fad394235 326 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 276 291 1.4E-5 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS33480 15e17377d28fb3146e33979fad394235 326 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 230 245 1.4E-5 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS02765 c8ee0e12bb1e71d3912eabd8a2494c53 213 Pfam PF03358 NADPH-dependent FMN reductase 8 159 7.0E-37 T 29-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 SMALA_RS02765 c8ee0e12bb1e71d3912eabd8a2494c53 213 Gene3D G3DSA:3.40.50.360 4 189 1.8E-42 T 29-03-2018 IPR029039 Flavoprotein-like domain SMALA_RS02765 c8ee0e12bb1e71d3912eabd8a2494c53 213 TIGRFAM TIGR04037 LLM_duo_CE1759: LLM-partnered FMN reductase, CE1759 family 9 207 8.4E-85 T 29-03-2018 IPR023932 Uncharacterised protein family, CE1759 SMALA_RS02765 c8ee0e12bb1e71d3912eabd8a2494c53 213 SUPERFAMILY SSF52218 6 188 6.4E-31 T 29-03-2018 IPR029039 Flavoprotein-like domain SMALA_RS40720 570482823cb0048baf5f7bb04f9fb355 545 SUPERFAMILY SSF51905 289 378 3.16E-57 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS40720 570482823cb0048baf5f7bb04f9fb355 545 SUPERFAMILY SSF51905 16 200 3.16E-57 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS40720 570482823cb0048baf5f7bb04f9fb355 545 Gene3D G3DSA:3.50.50.60 13 416 2.3E-60 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS40720 570482823cb0048baf5f7bb04f9fb355 545 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 179 194 1.3E-37 T 29-03-2018 SMALA_RS40720 570482823cb0048baf5f7bb04f9fb355 545 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 353 369 1.3E-37 T 29-03-2018 SMALA_RS40720 570482823cb0048baf5f7bb04f9fb355 545 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 302 317 1.3E-37 T 29-03-2018 SMALA_RS40720 570482823cb0048baf5f7bb04f9fb355 545 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 317 333 1.3E-37 T 29-03-2018 SMALA_RS40720 570482823cb0048baf5f7bb04f9fb355 545 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 18 40 1.3E-37 T 29-03-2018 SMALA_RS40720 570482823cb0048baf5f7bb04f9fb355 545 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 335 353 1.3E-37 T 29-03-2018 SMALA_RS40720 570482823cb0048baf5f7bb04f9fb355 545 Pfam PF01494 FAD binding domain 16 366 7.7E-71 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 SMALA_RS02135 f7b7b75f123dd242893c0c53528b77a4 187 SUPERFAMILY SSF46689 2 78 3.49E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS02135 f7b7b75f123dd242893c0c53528b77a4 187 Gene3D G3DSA:1.10.357.10 57 187 3.7E-20 T 29-03-2018 SMALA_RS02135 f7b7b75f123dd242893c0c53528b77a4 187 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 51 2.4E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS02135 f7b7b75f123dd242893c0c53528b77a4 187 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 7 20 2.4E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS02135 f7b7b75f123dd242893c0c53528b77a4 187 Gene3D G3DSA:1.10.10.60 1 56 1.5E-14 T 29-03-2018 SMALA_RS02135 f7b7b75f123dd242893c0c53528b77a4 187 SUPERFAMILY SSF48498 74 182 3.98E-20 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS02135 f7b7b75f123dd242893c0c53528b77a4 187 Pfam PF00440 Bacterial regulatory proteins, tetR family 7 53 5.2E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS32110 98674f115f2d181b926f7fbb447ac766 648 Gene3D G3DSA:1.50.10.20 2 52 0.0058 T 29-03-2018 SMALA_RS32110 98674f115f2d181b926f7fbb447ac766 648 Gene3D G3DSA:1.50.10.20 307 644 1.4E-112 T 29-03-2018 SMALA_RS32110 98674f115f2d181b926f7fbb447ac766 648 TIGRFAM TIGR01787 squalene_cyclas: squalene/oxidosqualene cyclases 25 635 9.4E-182 T 29-03-2018 IPR018333 Squalene cyclase GO:0016866 Reactome: R-HSA-191273|Reactome: R-HSA-2426168 SMALA_RS32110 98674f115f2d181b926f7fbb447ac766 648 Pfam PF13249 Squalene-hopene cyclase N-terminal domain 26 311 2.9E-124 T 29-03-2018 IPR032697 Squalene cyclase, N-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 SMALA_RS32110 98674f115f2d181b926f7fbb447ac766 648 SUPERFAMILY SSF48239 308 637 1.33E-103 T 29-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid SMALA_RS32110 98674f115f2d181b926f7fbb447ac766 648 TIGRFAM TIGR01507 hopene_cyclase: squalene-hopene cyclase 14 637 1.5E-238 T 29-03-2018 IPR006400 Squalene hopene cyclase GO:0016866|GO:0019746 KEGG: 00030+4.2.1.12|KEGG: 00909+4.2.1.129+5.4.99.17|MetaCyc: PWY-6098|MetaCyc: PWY-7072 SMALA_RS32110 98674f115f2d181b926f7fbb447ac766 648 Gene3D G3DSA:1.50.10.20 53 306 5.1E-85 T 29-03-2018 SMALA_RS32110 98674f115f2d181b926f7fbb447ac766 648 SUPERFAMILY SSF48239 49 315 1.31E-75 T 29-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid SMALA_RS32110 98674f115f2d181b926f7fbb447ac766 648 Pfam PF13243 Squalene-hopene cyclase C-terminal domain 321 635 6.1E-136 T 29-03-2018 IPR032696 Squalene cyclase, C-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 SMALA_RS27995 25ad9d61ab1c7343b9420a9532575045 195 Gene3D G3DSA:3.40.50.150 1 191 2.2E-32 T 29-03-2018 SMALA_RS27995 25ad9d61ab1c7343b9420a9532575045 195 PIRSF PIRSF004553 1 188 1.4E-50 T 29-03-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 SMALA_RS27995 25ad9d61ab1c7343b9420a9532575045 195 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 2 184 2.2E-44 T 29-03-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 SMALA_RS27995 25ad9d61ab1c7343b9420a9532575045 195 SUPERFAMILY SSF53335 2 182 2.05E-43 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS27995 25ad9d61ab1c7343b9420a9532575045 195 Pfam PF03602 Conserved hypothetical protein 95 2 184 4.3E-51 T 29-03-2018 SMALA_RS27995 25ad9d61ab1c7343b9420a9532575045 195 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 120 126 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 SMALA_RS20065 879800b772246fd0804eb7070e49bb2e 274 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 17 153 1.1E-21 T 29-03-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 SMALA_RS20065 879800b772246fd0804eb7070e49bb2e 274 SUPERFAMILY SSF55718 200 270 1.11E-6 T 29-03-2018 IPR003033 SCP2 sterol-binding domain SMALA_RS20065 879800b772246fd0804eb7070e49bb2e 274 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 14 244 2.0E-38 T 29-03-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type SMALA_RS20065 879800b772246fd0804eb7070e49bb2e 274 Pfam PF07398 MDMPI C-terminal domain 172 264 2.6E-9 T 29-03-2018 IPR010872 MDMPI C-terminal SMALA_RS20065 879800b772246fd0804eb7070e49bb2e 274 Gene3D G3DSA:3.30.1050.10 161 274 6.2E-6 T 29-03-2018 IPR003033 SCP2 sterol-binding domain SMALA_RS20065 879800b772246fd0804eb7070e49bb2e 274 Gene3D G3DSA:1.20.120.450 4 158 1.1E-24 T 29-03-2018 SMALA_RS20065 879800b772246fd0804eb7070e49bb2e 274 SUPERFAMILY SSF109854 4 158 5.26E-34 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes SMALA_RS06425 fb9407c7542bb4543bf48596cc7ee1b3 159 SUPERFAMILY SSF55961 11 146 1.1E-15 T 29-03-2018 SMALA_RS06425 fb9407c7542bb4543bf48596cc7ee1b3 159 Pfam PF08982 Domain of unknown function (DUF1857) 6 146 2.1E-14 T 29-03-2018 IPR015075 Acetylaranotin biosynthesis cluster protein L SMALA_RS06425 fb9407c7542bb4543bf48596cc7ee1b3 159 Gene3D G3DSA:3.30.530.20 5 156 3.3E-25 T 29-03-2018 IPR023393 START-like domain SMALA_RS07955 92548ba1fae680e553d2eeb8281481e0 182 SUPERFAMILY SSF88946 19 88 2.39E-9 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS07955 92548ba1fae680e553d2eeb8281481e0 182 Gene3D G3DSA:1.10.10.10 109 181 1.9E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS07955 92548ba1fae680e553d2eeb8281481e0 182 Gene3D G3DSA:1.10.1740.10 8 106 3.1E-11 T 29-03-2018 SMALA_RS07955 92548ba1fae680e553d2eeb8281481e0 182 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 22 177 6.9E-22 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS07955 92548ba1fae680e553d2eeb8281481e0 182 Pfam PF04542 Sigma-70 region 2 36 92 3.2E-8 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS07955 92548ba1fae680e553d2eeb8281481e0 182 Pfam PF08281 Sigma-70, region 4 122 173 2.7E-11 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS07955 92548ba1fae680e553d2eeb8281481e0 182 SUPERFAMILY SSF88659 109 179 4.86E-13 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS36495 0f9894bc7f98a3e439adf5ee48478054 390 Gene3D G3DSA:3.30.420.40 196 373 7.0E-25 T 29-03-2018 SMALA_RS36495 0f9894bc7f98a3e439adf5ee48478054 390 Gene3D G3DSA:3.30.420.40 1 186 1.3E-50 T 29-03-2018 SMALA_RS36495 0f9894bc7f98a3e439adf5ee48478054 390 SUPERFAMILY SSF53067 70 110 4.23E-12 T 29-03-2018 SMALA_RS36495 0f9894bc7f98a3e439adf5ee48478054 390 SUPERFAMILY SSF53067 1 35 4.23E-12 T 29-03-2018 SMALA_RS36495 0f9894bc7f98a3e439adf5ee48478054 390 SUPERFAMILY SSF53067 143 321 4.23E-12 T 29-03-2018 SMALA_RS36495 0f9894bc7f98a3e439adf5ee48478054 390 Pfam PF03702 Anhydro-N-acetylmuramic acid kinase 1 367 4.2E-115 T 29-03-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 KEGG: 00040+2.7.1.17 SMALA_RS36495 0f9894bc7f98a3e439adf5ee48478054 390 Hamap MF_01270 Anhydro-N-acetylmuramic acid kinase [anmK]. 1 368 34.73 T 29-03-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 KEGG: 00040+2.7.1.17 SMALA_RS22690 f5338ae1560dd27b7a5d3c757c0f8e19 287 SUPERFAMILY SSF55120 9 262 1.58E-72 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 SMALA_RS22690 f5338ae1560dd27b7a5d3c757c0f8e19 287 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 12 252 5.8E-52 T 29-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 SMALA_RS22690 f5338ae1560dd27b7a5d3c757c0f8e19 287 Gene3D G3DSA:3.30.70.580 9 118 3.0E-35 T 29-03-2018 SMALA_RS22690 f5338ae1560dd27b7a5d3c757c0f8e19 287 Pfam PF01416 tRNA pseudouridine synthase 157 259 1.1E-23 T 29-03-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 SMALA_RS22690 f5338ae1560dd27b7a5d3c757c0f8e19 287 Pfam PF01416 tRNA pseudouridine synthase 17 116 9.8E-6 T 29-03-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 SMALA_RS22690 f5338ae1560dd27b7a5d3c757c0f8e19 287 PIRSF PIRSF001430 10 275 1.1E-75 T 29-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 SMALA_RS22690 f5338ae1560dd27b7a5d3c757c0f8e19 287 Gene3D G3DSA:3.30.70.660 119 257 7.2E-31 T 29-03-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 SMALA_RS22690 f5338ae1560dd27b7a5d3c757c0f8e19 287 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 10 258 31.209 T 29-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 SMALA_RS23420 fcd094032e3f1c86ad96d4c8fa4ffa8d 142 SUPERFAMILY SSF54593 6 120 9.8E-21 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS23420 fcd094032e3f1c86ad96d4c8fa4ffa8d 142 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 85 7.6E-11 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMALA_RS23420 fcd094032e3f1c86ad96d4c8fa4ffa8d 142 Gene3D G3DSA:3.10.180.10 4 126 2.7E-18 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS07160 5a70783231027dd096ccd17bbc1a082a 382 Pfam PF00005 ABC transporter 44 190 3.9E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS07160 5a70783231027dd096ccd17bbc1a082a 382 SUPERFAMILY SSF54631 294 351 2.1E-5 T 29-03-2018 SMALA_RS07160 5a70783231027dd096ccd17bbc1a082a 382 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 35 291 8.7E-111 T 29-03-2018 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 SMALA_RS07160 5a70783231027dd096ccd17bbc1a082a 382 SUPERFAMILY SSF52540 41 268 1.49E-75 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS07160 5a70783231027dd096ccd17bbc1a082a 382 SMART SM00382 51 248 4.8E-18 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS07160 5a70783231027dd096ccd17bbc1a082a 382 Gene3D G3DSA:3.40.50.300 2 280 1.3E-71 T 29-03-2018 SMALA_RS07160 5a70783231027dd096ccd17bbc1a082a 382 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS07160 5a70783231027dd096ccd17bbc1a082a 382 Gene3D G3DSA:3.20.20.70 287 368 3.8E-4 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS12975 47e29ae076bcac2e1d00ec70090ddbdd 698 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 463 697 3.2E-41 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS12975 47e29ae076bcac2e1d00ec70090ddbdd 698 Gene3D G3DSA:3.30.450.40 252 414 4.5E-21 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS12975 47e29ae076bcac2e1d00ec70090ddbdd 698 Gene3D G3DSA:3.30.565.10 30 187 6.0E-10 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS12975 47e29ae076bcac2e1d00ec70090ddbdd 698 Gene3D G3DSA:3.60.40.10 415 698 1.1E-32 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS12975 47e29ae076bcac2e1d00ec70090ddbdd 698 Pfam PF13581 Histidine kinase-like ATPase domain 51 168 9.5E-9 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS12975 47e29ae076bcac2e1d00ec70090ddbdd 698 SMART SM00331 437 697 1.2E-36 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS12975 47e29ae076bcac2e1d00ec70090ddbdd 698 SUPERFAMILY SSF55781 295 415 3.66E-6 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS04720 eaec0130302678ac971c700636304dc0 276 SUPERFAMILY SSF161098 29 267 4.58E-51 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS04720 eaec0130302678ac971c700636304dc0 276 Gene3D G3DSA:1.10.3720.10 39 276 8.5E-39 T 29-03-2018 SMALA_RS04720 eaec0130302678ac971c700636304dc0 276 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 71 269 8.3E-13 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS00050 9607e729b395ce413cb1b3f74fa123a4 650 Gene3D G3DSA:3.40.50.300 293 646 2.8E-12 T 29-03-2018 SMALA_RS00050 9607e729b395ce413cb1b3f74fa123a4 650 SUPERFAMILY SSF52540 283 634 3.24E-10 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS16290 018fe99903ec7fb61d584d254b3b994c 260 Gene3D G3DSA:3.10.180.10 6 129 3.2E-15 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS16290 018fe99903ec7fb61d584d254b3b994c 260 SUPERFAMILY SSF54593 12 171 1.61E-18 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS16290 018fe99903ec7fb61d584d254b3b994c 260 Gene3D G3DSA:3.10.180.10 142 260 1.7E-19 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS16290 018fe99903ec7fb61d584d254b3b994c 260 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 148 251 6.3E-6 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMALA_RS16290 018fe99903ec7fb61d584d254b3b994c 260 SUPERFAMILY SSF54593 143 255 1.75E-21 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS37650 3fa3c7586a55f2dfbbb73bf24290fcf4 842 Gene3D G3DSA:3.40.50.300 18 201 3.3E-27 T 29-03-2018 SMALA_RS37650 3fa3c7586a55f2dfbbb73bf24290fcf4 842 Pfam PF00270 DEAD/DEAH box helicase 33 180 5.1E-10 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 SMALA_RS37650 3fa3c7586a55f2dfbbb73bf24290fcf4 842 SMART SM00490 277 363 1.5E-12 T 29-03-2018 IPR001650 Helicase, C-terminal SMALA_RS37650 3fa3c7586a55f2dfbbb73bf24290fcf4 842 SMART SM00487 27 212 1.4E-17 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain SMALA_RS37650 3fa3c7586a55f2dfbbb73bf24290fcf4 842 Pfam PF00271 Helicase conserved C-terminal domain 241 363 3.0E-6 T 29-03-2018 IPR001650 Helicase, C-terminal SMALA_RS37650 3fa3c7586a55f2dfbbb73bf24290fcf4 842 SUPERFAMILY SSF52540 44 250 3.63E-41 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS37650 3fa3c7586a55f2dfbbb73bf24290fcf4 842 SUPERFAMILY SSF52540 283 375 3.63E-41 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS37650 3fa3c7586a55f2dfbbb73bf24290fcf4 842 Gene3D G3DSA:3.40.50.300 207 406 4.7E-18 T 29-03-2018 SMALA_RS37650 3fa3c7586a55f2dfbbb73bf24290fcf4 842 Pfam PF12029 Domain of unknown function (DUF3516) 374 839 2.4E-214 T 29-03-2018 IPR021904 Protein of unknown function DUF3516 SMALA_RS40130 af61d3fc005d5b4bc756d690816b5269 285 Gene3D G3DSA:1.10.3720.10 6 272 8.3E-40 T 29-03-2018 SMALA_RS40130 af61d3fc005d5b4bc756d690816b5269 285 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 98 276 6.6E-24 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS40130 af61d3fc005d5b4bc756d690816b5269 285 SUPERFAMILY SSF161098 7 284 2.22E-67 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS35160 003c597733df488c29fdf61a8f17cf7e 252 SUPERFAMILY SSF55729 16 223 5.83E-36 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS35160 003c597733df488c29fdf61a8f17cf7e 252 Pfam PF13444 Acetyltransferase (GNAT) domain 33 132 3.4E-29 T 29-03-2018 SMALA_RS35160 003c597733df488c29fdf61a8f17cf7e 252 Gene3D G3DSA:3.40.630.30 12 201 6.9E-34 T 29-03-2018 SMALA_RS43310 d47f10383ba1ea40f9f9ecb24be56178 343 Gene3D G3DSA:1.10.530.10 9 185 2.8E-35 T 29-03-2018 SMALA_RS43310 d47f10383ba1ea40f9f9ecb24be56178 343 SUPERFAMILY SSF54001 201 341 7.19E-29 T 29-03-2018 SMALA_RS43310 d47f10383ba1ea40f9f9ecb24be56178 343 Gene3D G3DSA:3.90.1720.10 202 342 5.7E-29 T 29-03-2018 SMALA_RS43310 d47f10383ba1ea40f9f9ecb24be56178 343 Pfam PF00877 NlpC/P60 family 222 327 2.2E-18 T 29-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain SMALA_RS43310 d47f10383ba1ea40f9f9ecb24be56178 343 Pfam PF01464 Transglycosylase SLT domain 46 153 6.9E-12 T 29-03-2018 IPR008258 Transglycosylase SLT domain 1 SMALA_RS43310 d47f10383ba1ea40f9f9ecb24be56178 343 SUPERFAMILY SSF53955 37 176 4.28E-30 T 29-03-2018 IPR023346 Lysozyme-like domain SMALA_RS16450 6abd51344c28741636261684e3054627 524 SMART SM00388 261 328 1.4E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS16450 6abd51344c28741636261684e3054627 524 SMART SM00304 201 253 5.2E-14 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMALA_RS16450 6abd51344c28741636261684e3054627 524 Pfam PF00672 HAMP domain 202 249 2.3E-11 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMALA_RS16450 6abd51344c28741636261684e3054627 524 SMART SM00387 368 477 9.9E-33 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS16450 6abd51344c28741636261684e3054627 524 SUPERFAMILY SSF47384 245 328 5.3E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS16450 6abd51344c28741636261684e3054627 524 Gene3D G3DSA:1.10.287.130 251 317 9.5E-15 T 29-03-2018 SMALA_RS16450 6abd51344c28741636261684e3054627 524 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 369 476 2.6E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS16450 6abd51344c28741636261684e3054627 524 SUPERFAMILY SSF158472 203 250 4.32E-8 T 29-03-2018 SMALA_RS16450 6abd51344c28741636261684e3054627 524 Gene3D G3DSA:3.30.565.10 318 487 2.2E-35 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS16450 6abd51344c28741636261684e3054627 524 Pfam PF00512 His Kinase A (phospho-acceptor) domain 262 328 5.4E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS16450 6abd51344c28741636261684e3054627 524 SUPERFAMILY SSF55874 318 475 1.44E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS16450 6abd51344c28741636261684e3054627 524 PRINTS PR00344 Bacterial sensor protein C-terminal signature 461 474 1.3E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS16450 6abd51344c28741636261684e3054627 524 PRINTS PR00344 Bacterial sensor protein C-terminal signature 421 431 1.3E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS16450 6abd51344c28741636261684e3054627 524 PRINTS PR00344 Bacterial sensor protein C-terminal signature 403 417 1.3E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS16450 6abd51344c28741636261684e3054627 524 PRINTS PR00344 Bacterial sensor protein C-terminal signature 437 455 1.3E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS35230 0e275da941bfd10ee09b9cb68dae3194 355 SUPERFAMILY SSF50129 1 162 2.13E-51 T 29-03-2018 IPR011032 GroES-like SMALA_RS35230 0e275da941bfd10ee09b9cb68dae3194 355 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 128 7.8E-28 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS35230 0e275da941bfd10ee09b9cb68dae3194 355 SUPERFAMILY SSF51735 144 308 6.39E-38 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS35230 0e275da941bfd10ee09b9cb68dae3194 355 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 SMALA_RS35230 0e275da941bfd10ee09b9cb68dae3194 355 Gene3D G3DSA:3.40.50.720 168 290 2.9E-27 T 29-03-2018 SMALA_RS35230 0e275da941bfd10ee09b9cb68dae3194 355 Gene3D G3DSA:3.90.180.10 1 167 2.0E-46 T 29-03-2018 SMALA_RS35230 0e275da941bfd10ee09b9cb68dae3194 355 SMART SM00829 8 343 0.0013 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS35230 0e275da941bfd10ee09b9cb68dae3194 355 Pfam PF00107 Zinc-binding dehydrogenase 178 293 2.9E-25 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMALA_RS05050 8235155f70eab242a2c855d2b794e83f 234 SUPERFAMILY SSF52172 6 183 1.01E-41 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS05050 8235155f70eab242a2c855d2b794e83f 234 Gene3D G3DSA:3.40.50.2300 2 128 3.2E-36 T 29-03-2018 SMALA_RS05050 8235155f70eab242a2c855d2b794e83f 234 Pfam PF00486 Transcriptional regulatory protein, C terminal 155 229 2.5E-26 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS05050 8235155f70eab242a2c855d2b794e83f 234 Pfam PF00072 Response regulator receiver domain 8 121 2.2E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS05050 8235155f70eab242a2c855d2b794e83f 234 SMART SM00862 155 229 1.6E-27 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS05050 8235155f70eab242a2c855d2b794e83f 234 Gene3D G3DSA:1.10.10.10 129 234 1.5E-35 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS05050 8235155f70eab242a2c855d2b794e83f 234 SMART SM00448 5 121 2.5E-43 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS12530 bc30fde3b529d5f0e9b69a50a0f4672f 400 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 9 399 1.7E-131 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 SMALA_RS12530 bc30fde3b529d5f0e9b69a50a0f4672f 400 PIRSF PIRSF000429 1 400 4.5E-126 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 SMALA_RS12530 bc30fde3b529d5f0e9b69a50a0f4672f 400 ProSitePatterns PS00099 Thiolases active site. 382 395 - T 29-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 SMALA_RS12530 bc30fde3b529d5f0e9b69a50a0f4672f 400 SUPERFAMILY SSF53901 6 272 8.96E-77 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS12530 bc30fde3b529d5f0e9b69a50a0f4672f 400 ProSitePatterns PS00737 Thiolases signature 2. 347 363 - T 29-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 SMALA_RS12530 bc30fde3b529d5f0e9b69a50a0f4672f 400 SUPERFAMILY SSF53901 274 400 4.87E-35 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS12530 bc30fde3b529d5f0e9b69a50a0f4672f 400 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 89 107 - T 29-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 SMALA_RS12530 bc30fde3b529d5f0e9b69a50a0f4672f 400 Pfam PF02803 Thiolase, C-terminal domain 274 400 1.4E-36 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 SMALA_RS12530 bc30fde3b529d5f0e9b69a50a0f4672f 400 Pfam PF00108 Thiolase, N-terminal domain 7 266 1.9E-72 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 SMALA_RS12530 bc30fde3b529d5f0e9b69a50a0f4672f 400 Gene3D G3DSA:3.40.47.10 162 280 2.9E-22 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS12530 bc30fde3b529d5f0e9b69a50a0f4672f 400 Gene3D G3DSA:3.40.47.10 281 398 1.9E-23 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS12530 bc30fde3b529d5f0e9b69a50a0f4672f 400 Gene3D G3DSA:3.40.47.10 1 148 7.7E-33 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS36335 1165c1e95ed0bc9870409579b7837327 629 SUPERFAMILY SSF49785 54 180 1.56E-28 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS36335 1165c1e95ed0bc9870409579b7837327 629 Gene3D G3DSA:2.60.120.260 185 352 1.7E-29 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS36335 1165c1e95ed0bc9870409579b7837327 629 Pfam PF00722 Glycosyl hydrolases family 16 406 624 4.2E-33 T 29-03-2018 IPR000757 Glycoside hydrolase family 16 GO:0004553|GO:0005975 SMALA_RS36335 1165c1e95ed0bc9870409579b7837327 629 SUPERFAMILY SSF49785 189 350 5.25E-20 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS36335 1165c1e95ed0bc9870409579b7837327 629 Gene3D G3DSA:2.60.120.260 34 184 4.1E-31 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS36335 1165c1e95ed0bc9870409579b7837327 629 Gene3D G3DSA:2.60.120.200 354 629 2.0E-64 T 29-03-2018 SMALA_RS36335 1165c1e95ed0bc9870409579b7837327 629 SUPERFAMILY SSF49899 366 628 6.89E-65 T 29-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain SMALA_RS36335 1165c1e95ed0bc9870409579b7837327 629 Pfam PF00754 F5/8 type C domain 60 174 1.3E-24 T 29-03-2018 IPR000421 Coagulation factor 5/8 C-terminal domain SMALA_RS36335 1165c1e95ed0bc9870409579b7837327 629 Pfam PF00754 F5/8 type C domain 211 329 3.6E-24 T 29-03-2018 IPR000421 Coagulation factor 5/8 C-terminal domain SMALA_RS29445 c14a55f100e15c90f6012537daf30921 147 SUPERFAMILY SSF54637 38 126 1.25E-17 T 29-03-2018 IPR029069 HotDog domain SMALA_RS29445 c14a55f100e15c90f6012537daf30921 147 Pfam PF07977 FabA-like domain 46 114 3.1E-6 T 29-03-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 SMALA_RS29445 c14a55f100e15c90f6012537daf30921 147 Gene3D G3DSA:3.10.129.10 27 145 1.2E-19 T 29-03-2018 SMALA_RS23585 8db30870b63589a047a1143930260e31 199 SUPERFAMILY SSF55729 15 181 1.15E-39 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS23585 8db30870b63589a047a1143930260e31 199 SMART SM01006 20 67 1.2E-13 T 29-03-2018 IPR019432 Siderophore biosynthesis protein, conserved domain SMALA_RS23585 8db30870b63589a047a1143930260e31 199 Gene3D G3DSA:3.40.630.30 2 184 4.8E-16 T 29-03-2018 SMALA_RS23585 8db30870b63589a047a1143930260e31 199 Pfam PF13523 Acetyltransferase (GNAT) domain 23 165 7.6E-49 T 29-03-2018 SMALA_RS11760 f44ac73e0edbe7b3a51557f3f5be4acd 317 SUPERFAMILY SSF50129 1 147 2.04E-36 T 29-03-2018 IPR011032 GroES-like SMALA_RS11760 f44ac73e0edbe7b3a51557f3f5be4acd 317 Gene3D G3DSA:3.90.180.10 237 317 0.09 T 29-03-2018 SMALA_RS11760 f44ac73e0edbe7b3a51557f3f5be4acd 317 Pfam PF13602 Zinc-binding dehydrogenase 197 315 2.4E-7 T 29-03-2018 SMALA_RS11760 f44ac73e0edbe7b3a51557f3f5be4acd 317 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 91 6.8E-9 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS11760 f44ac73e0edbe7b3a51557f3f5be4acd 317 Gene3D G3DSA:3.40.50.720 145 236 1.7E-13 T 29-03-2018 SMALA_RS11760 f44ac73e0edbe7b3a51557f3f5be4acd 317 SUPERFAMILY SSF51735 116 242 1.0E-21 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS11760 f44ac73e0edbe7b3a51557f3f5be4acd 317 Gene3D G3DSA:3.90.180.10 1 144 1.1E-42 T 29-03-2018 SMALA_RS11760 f44ac73e0edbe7b3a51557f3f5be4acd 317 SMART SM00829 10 315 1.7E-13 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS27135 1a22a864e265a97aea08401aad0e639c 323 Gene3D G3DSA:1.25.40.10 248 323 0.28 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS27135 1a22a864e265a97aea08401aad0e639c 323 Gene3D G3DSA:3.40.30.10 43 247 4.0E-43 T 29-03-2018 SMALA_RS27135 1a22a864e265a97aea08401aad0e639c 323 ProSitePatterns PS00194 Thioredoxin family active site. 69 87 - T 29-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 SMALA_RS27135 1a22a864e265a97aea08401aad0e639c 323 SUPERFAMILY SSF52833 47 153 4.36E-31 T 29-03-2018 IPR012336 Thioredoxin-like fold SMALA_RS27135 1a22a864e265a97aea08401aad0e639c 323 Pfam PF14561 Tetratricopeptide repeat 237 323 2.2E-21 T 29-03-2018 SMALA_RS27135 1a22a864e265a97aea08401aad0e639c 323 Pfam PF00085 Thioredoxin 49 150 6.2E-24 T 29-03-2018 IPR013766 Thioredoxin domain GO:0045454 SMALA_RS27135 1a22a864e265a97aea08401aad0e639c 323 Pfam PF14559 Tetratricopeptide repeat 197 232 5.6E-6 T 29-03-2018 SMALA_RS23440 6d82c0d73147446c311f4ae3c3eaffd3 1069 Gene3D G3DSA:2.60.40.1180 544 701 3.9E-6 T 29-03-2018 SMALA_RS23440 6d82c0d73147446c311f4ae3c3eaffd3 1069 SUPERFAMILY SSF74650 685 1038 2.29E-16 T 29-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 SMALA_RS23440 6d82c0d73147446c311f4ae3c3eaffd3 1069 SUPERFAMILY SSF74650 562 652 2.29E-16 T 29-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 SMALA_RS23440 6d82c0d73147446c311f4ae3c3eaffd3 1069 Gene3D G3DSA:3.20.110.10 105 339 2.5E-28 T 29-03-2018 IPR027291 Glycoside hydrolase 38/57, N-terminal domain SMALA_RS23440 6d82c0d73147446c311f4ae3c3eaffd3 1069 Pfam PF07748 Glycosyl hydrolases family 38 C-terminal domain 570 837 9.7E-9 T 29-03-2018 IPR011682 Glycosyl hydrolase family 38, C-terminal GO:0004559|GO:0006013 SMALA_RS23440 6d82c0d73147446c311f4ae3c3eaffd3 1069 SUPERFAMILY SSF88713 124 332 6.12E-23 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 SMALA_RS23440 6d82c0d73147446c311f4ae3c3eaffd3 1069 Pfam PF01074 Glycosyl hydrolases family 38 N-terminal domain 130 317 1.3E-11 T 29-03-2018 IPR000602 Glycoside hydrolase family 38, N-terminal domain GO:0004559|GO:0006013 SMALA_RS36715 ed8b220c72cec0891abfcc33211773bb 4047 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3917 3932 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS36715 ed8b220c72cec0891abfcc33211773bb 4047 SUPERFAMILY SSF47336 3882 3972 2.88E-23 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS36715 ed8b220c72cec0891abfcc33211773bb 4047 Gene3D G3DSA:1.10.1200.10 3858 3968 9.8E-20 T 29-03-2018 SMALA_RS36715 ed8b220c72cec0891abfcc33211773bb 4047 Gene3D G3DSA:3.40.50.720 3418 3524 6.6E-20 T 29-03-2018 SMALA_RS36715 ed8b220c72cec0891abfcc33211773bb 4047 SMART SM00825 Beta-ketoacyl synthase 1843 2269 1.8E-227 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS36715 ed8b220c72cec0891abfcc33211773bb 4047 SMART SM00825 Beta-ketoacyl synthase 38 462 1.0E-221 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS36715 ed8b220c72cec0891abfcc33211773bb 4047 SUPERFAMILY SSF51735 3054 3264 9.45E-25 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS36715 ed8b220c72cec0891abfcc33211773bb 4047 Gene3D G3DSA:3.90.180.10 3525 3598 0.0015 T 29-03-2018 SMALA_RS36715 ed8b220c72cec0891abfcc33211773bb 4047 SMART SM00826 2749 2916 1.5E-80 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS36715 ed8b220c72cec0891abfcc33211773bb 4047 SMART SM00826 936 1110 1.8E-70 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS36715 ed8b220c72cec0891abfcc33211773bb 4047 Pfam PF14765 Polyketide synthase dehydratase 2749 3043 5.9E-52 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS36715 ed8b220c72cec0891abfcc33211773bb 4047 Pfam PF14765 Polyketide synthase dehydratase 936 1233 3.2E-50 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS36715 ed8b220c72cec0891abfcc33211773bb 4047 SUPERFAMILY SSF51735 3602 3852 1.33E-43 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS36715 ed8b220c72cec0891abfcc33211773bb 4047 Gene3D G3DSA:3.40.50.720 1463 1698 2.0E-42 T 29-03-2018 SMALA_RS36715 ed8b220c72cec0891abfcc33211773bb 4047 Gene3D G3DSA:3.40.50.720 3599 3857 1.4E-44 T 29-03-2018 SMALA_RS36715 ed8b220c72cec0891abfcc33211773bb 4047 SUPERFAMILY SSF47336 1745 1856 1.44E-23 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS36715 ed8b220c72cec0891abfcc33211773bb 4047 SMART SM00823 Phosphopantetheine attachment site 3890 3962 1.6E-32 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS36715 ed8b220c72cec0891abfcc33211773bb 4047 SMART SM00823 Phosphopantetheine attachment site 1750 1822 1.5E-31 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS36715 ed8b220c72cec0891abfcc33211773bb 4047 SUPERFAMILY SSF51735 3388 3566 5.01E-38 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS36715 ed8b220c72cec0891abfcc33211773bb 4047 SUPERFAMILY SSF53901 33 407 1.67E-103 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS36715 ed8b220c72cec0891abfcc33211773bb 4047 Gene3D G3DSA:1.10.1200.10 1747 1839 4.2E-19 T 29-03-2018 SMALA_RS36715 ed8b220c72cec0891abfcc33211773bb 4047 Gene3D G3DSA:3.40.366.10 747 869 7.0E-25 T 29-03-2018 SMALA_RS36715 ed8b220c72cec0891abfcc33211773bb 4047 Gene3D G3DSA:3.40.366.10 2559 2680 7.0E-24 T 29-03-2018 SMALA_RS36715 ed8b220c72cec0891abfcc33211773bb 4047 SUPERFAMILY SSF52151 2569 2674 9.94E-63 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS36715 ed8b220c72cec0891abfcc33211773bb 4047 SUPERFAMILY SSF52151 2375 2502 9.94E-63 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS36715 ed8b220c72cec0891abfcc33211773bb 4047 SMART SM00829 3289 3595 3.7E-180 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS36715 ed8b220c72cec0891abfcc33211773bb 4047 Pfam PF08990 Erythronolide synthase docking 5 28 1.2E-10 T 29-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 SMALA_RS36715 ed8b220c72cec0891abfcc33211773bb 4047 Pfam PF00698 Acyl transferase domain 2376 2699 1.6E-82 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS36715 ed8b220c72cec0891abfcc33211773bb 4047 Pfam PF00698 Acyl transferase domain 567 887 2.7E-80 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS36715 ed8b220c72cec0891abfcc33211773bb 4047 Gene3D G3DSA:3.10.129.10 940 1064 1.2E-6 T 29-03-2018 SMALA_RS36715 ed8b220c72cec0891abfcc33211773bb 4047 Gene3D G3DSA:3.10.129.10 2751 2877 3.4E-7 T 29-03-2018 SMALA_RS36715 ed8b220c72cec0891abfcc33211773bb 4047 Gene3D G3DSA:3.40.366.10 564 700 2.3E-39 T 29-03-2018 SMALA_RS36715 ed8b220c72cec0891abfcc33211773bb 4047 Gene3D G3DSA:3.40.366.10 2371 2514 3.0E-43 T 29-03-2018 SMALA_RS36715 ed8b220c72cec0891abfcc33211773bb 4047 Pfam PF08659 KR domain 3605 3784 5.1E-54 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS36715 ed8b220c72cec0891abfcc33211773bb 4047 Pfam PF08659 KR domain 1471 1649 1.3E-55 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS36715 ed8b220c72cec0891abfcc33211773bb 4047 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 3309 3364 5.9E-5 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS36715 ed8b220c72cec0891abfcc33211773bb 4047 SUPERFAMILY SSF55048 688 756 1.44E-10 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS36715 ed8b220c72cec0891abfcc33211773bb 4047 Pfam PF00550 Phosphopantetheine attachment site 3893 3957 8.2E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS36715 ed8b220c72cec0891abfcc33211773bb 4047 Pfam PF00550 Phosphopantetheine attachment site 1752 1818 1.2E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS36715 ed8b220c72cec0891abfcc33211773bb 4047 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3605 3785 4.0E-48 T 29-03-2018 SMALA_RS36715 ed8b220c72cec0891abfcc33211773bb 4047 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1471 1651 6.7E-49 T 29-03-2018 SMALA_RS36715 ed8b220c72cec0891abfcc33211773bb 4047 SUPERFAMILY SSF50129 3296 3421 1.35E-25 T 29-03-2018 IPR011032 GroES-like SMALA_RS36715 ed8b220c72cec0891abfcc33211773bb 4047 SUPERFAMILY SSF55048 2500 2568 1.14E-10 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS36715 ed8b220c72cec0891abfcc33211773bb 4047 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 2004 2020 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS36715 ed8b220c72cec0891abfcc33211773bb 4047 Gene3D G3DSA:3.30.70.250 701 746 1.4E-14 T 29-03-2018 SMALA_RS36715 ed8b220c72cec0891abfcc33211773bb 4047 Gene3D G3DSA:3.30.70.250 2515 2558 1.1E-14 T 29-03-2018 SMALA_RS36715 ed8b220c72cec0891abfcc33211773bb 4047 SUPERFAMILY SSF51735 1468 1675 4.74E-41 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS36715 ed8b220c72cec0891abfcc33211773bb 4047 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1777 1792 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS36715 ed8b220c72cec0891abfcc33211773bb 4047 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1841 2091 3.7E-88 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS36715 ed8b220c72cec0891abfcc33211773bb 4047 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 36 284 7.4E-89 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS36715 ed8b220c72cec0891abfcc33211773bb 4047 SUPERFAMILY SSF52151 566 690 1.1E-60 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS36715 ed8b220c72cec0891abfcc33211773bb 4047 SUPERFAMILY SSF52151 757 862 1.1E-60 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS36715 ed8b220c72cec0891abfcc33211773bb 4047 SUPERFAMILY SSF51735 1241 1449 1.81E-28 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS36715 ed8b220c72cec0891abfcc33211773bb 4047 SUPERFAMILY SSF53901 1837 2212 1.82E-101 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS36715 ed8b220c72cec0891abfcc33211773bb 4047 Gene3D G3DSA:3.40.47.10 2106 2267 1.0E-63 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS36715 ed8b220c72cec0891abfcc33211773bb 4047 Gene3D G3DSA:3.40.47.10 299 460 3.1E-62 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS36715 ed8b220c72cec0891abfcc33211773bb 4047 SMART SM01294 3891 3958 9.6E-6 T 29-03-2018 SMALA_RS36715 ed8b220c72cec0891abfcc33211773bb 4047 SMART SM01294 1751 1818 1.8E-5 T 29-03-2018 SMALA_RS36715 ed8b220c72cec0891abfcc33211773bb 4047 Pfam PF13602 Zinc-binding dehydrogenase 3462 3595 4.8E-19 T 29-03-2018 SMALA_RS36715 ed8b220c72cec0891abfcc33211773bb 4047 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 197 213 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS36715 ed8b220c72cec0891abfcc33211773bb 4047 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2099 2216 9.8E-45 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS36715 ed8b220c72cec0891abfcc33211773bb 4047 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 292 409 4.5E-44 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS36715 ed8b220c72cec0891abfcc33211773bb 4047 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2219 2335 2.5E-15 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS36715 ed8b220c72cec0891abfcc33211773bb 4047 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 414 527 2.3E-12 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS36715 ed8b220c72cec0891abfcc33211773bb 4047 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 568 868 1.7E-110 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS36715 ed8b220c72cec0891abfcc33211773bb 4047 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2377 2680 2.9E-115 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS36715 ed8b220c72cec0891abfcc33211773bb 4047 Gene3D G3DSA:3.40.47.10 1840 2103 1.9E-85 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS36715 ed8b220c72cec0891abfcc33211773bb 4047 Gene3D G3DSA:3.40.47.10 28 296 7.3E-84 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS36715 ed8b220c72cec0891abfcc33211773bb 4047 Gene3D G3DSA:3.90.180.10 3277 3417 8.8E-35 T 29-03-2018 SMALA_RS29360 a04a8cf991bd9eeed81e074575851390 704 PRINTS PR00097 Anthranilate synthase component II signature 4 18 2.8E-25 T 29-03-2018 SMALA_RS29360 a04a8cf991bd9eeed81e074575851390 704 PRINTS PR00097 Anthranilate synthase component II signature 50 59 2.8E-25 T 29-03-2018 SMALA_RS29360 a04a8cf991bd9eeed81e074575851390 704 PRINTS PR00097 Anthranilate synthase component II signature 123 135 2.8E-25 T 29-03-2018 SMALA_RS29360 a04a8cf991bd9eeed81e074575851390 704 PRINTS PR00097 Anthranilate synthase component II signature 167 180 2.8E-25 T 29-03-2018 SMALA_RS29360 a04a8cf991bd9eeed81e074575851390 704 PRINTS PR00097 Anthranilate synthase component II signature 78 89 2.8E-25 T 29-03-2018 SMALA_RS29360 a04a8cf991bd9eeed81e074575851390 704 SUPERFAMILY SSF56322 227 690 2.49E-132 T 29-03-2018 IPR005801 ADC synthase GO:0009058 SMALA_RS29360 a04a8cf991bd9eeed81e074575851390 704 Gene3D G3DSA:3.40.50.880 1 194 3.3E-52 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS29360 a04a8cf991bd9eeed81e074575851390 704 TIGRFAM TIGR00553 pabB: aminodeoxychorismate synthase, component I 332 685 7.2E-106 T 29-03-2018 IPR005802 Para-aminobenzoate synthase, component I GO:0009396 KEGG: 00790+2.6.1.85|MetaCyc: PWY-6543 SMALA_RS29360 a04a8cf991bd9eeed81e074575851390 704 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 5 188 1.2E-44 T 29-03-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 SMALA_RS29360 a04a8cf991bd9eeed81e074575851390 704 Pfam PF00425 chorismate binding enzyme 429 683 6.9E-88 T 29-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal SMALA_RS29360 a04a8cf991bd9eeed81e074575851390 704 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 47 61 1.9E-6 T 29-03-2018 SMALA_RS29360 a04a8cf991bd9eeed81e074575851390 704 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 78 94 1.9E-6 T 29-03-2018 SMALA_RS29360 a04a8cf991bd9eeed81e074575851390 704 Pfam PF00117 Glutamine amidotransferase class-I 6 187 6.1E-39 T 29-03-2018 IPR017926 Glutamine amidotransferase SMALA_RS29360 a04a8cf991bd9eeed81e074575851390 704 Pfam PF04715 Anthranilate synthase component I, N terminal region 240 376 1.4E-20 T 29-03-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 SMALA_RS29360 a04a8cf991bd9eeed81e074575851390 704 Gene3D G3DSA:3.60.120.10 224 695 8.2E-157 T 29-03-2018 IPR005801 ADC synthase GO:0009058 SMALA_RS29360 a04a8cf991bd9eeed81e074575851390 704 SUPERFAMILY SSF52317 2 189 1.83E-48 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS29360 a04a8cf991bd9eeed81e074575851390 704 PRINTS PR00096 Glutamine amidotransferase superfamily signature 50 59 3.3E-12 T 29-03-2018 SMALA_RS29360 a04a8cf991bd9eeed81e074575851390 704 PRINTS PR00096 Glutamine amidotransferase superfamily signature 167 180 3.3E-12 T 29-03-2018 SMALA_RS29360 a04a8cf991bd9eeed81e074575851390 704 PRINTS PR00096 Glutamine amidotransferase superfamily signature 78 89 3.3E-12 T 29-03-2018 SMALA_RS42855 e96b6534e2412f8e6f7e63def9320e7b 213 SUPERFAMILY SSF52218 1 167 1.57E-26 T 29-03-2018 IPR029039 Flavoprotein-like domain SMALA_RS42855 e96b6534e2412f8e6f7e63def9320e7b 213 TIGRFAM TIGR04037 LLM_duo_CE1759: LLM-partnered FMN reductase, CE1759 family 3 197 1.4E-74 T 29-03-2018 IPR023932 Uncharacterised protein family, CE1759 SMALA_RS42855 e96b6534e2412f8e6f7e63def9320e7b 213 Gene3D G3DSA:3.40.50.360 1 181 6.0E-35 T 29-03-2018 IPR029039 Flavoprotein-like domain SMALA_RS42855 e96b6534e2412f8e6f7e63def9320e7b 213 Pfam PF03358 NADPH-dependent FMN reductase 1 151 2.9E-35 T 29-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 SMALA_RS14320 300ce2ce1b2c30c7ec51495928a768bb 490 Pfam PF08388 Group II intron, maturase-specific domain 370 443 3.2E-17 T 29-03-2018 IPR013597 Group II intron, maturase-specific SMALA_RS14320 300ce2ce1b2c30c7ec51495928a768bb 490 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 54 433 2.1E-109 T 29-03-2018 IPR030931 Group II intron reverse transcriptase/maturase SMALA_RS14320 300ce2ce1b2c30c7ec51495928a768bb 490 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 113 346 1.8E-41 T 29-03-2018 IPR000477 Reverse transcriptase domain SMALA_RS14320 300ce2ce1b2c30c7ec51495928a768bb 490 Gene3D G3DSA:3.30.70.270 135 346 4.9E-31 T 29-03-2018 SMALA_RS14320 300ce2ce1b2c30c7ec51495928a768bb 490 SUPERFAMILY SSF56672 21 446 3.67E-52 T 29-03-2018 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 SUPERFAMILY SSF55048 6889 6938 3.53E-7 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 Gene3D G3DSA:3.40.366.10 1928 2038 1.4E-15 T 29-03-2018 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 SUPERFAMILY SSF51735 2823 3030 6.2E-40 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 Gene3D G3DSA:3.40.50.720 4322 4550 2.8E-45 T 29-03-2018 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 Gene3D G3DSA:3.40.50.720 2819 3053 1.2E-44 T 29-03-2018 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 Gene3D G3DSA:3.40.50.720 7508 7737 1.1E-45 T 29-03-2018 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 Gene3D G3DSA:3.40.50.720 5913 6142 9.6E-44 T 29-03-2018 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 SUPERFAMILY SSF50129 646 773 1.89E-25 T 29-03-2018 IPR011032 GroES-like SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5919 6091 4.6E-52 T 29-03-2018 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4328 4500 7.9E-55 T 29-03-2018 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7516 7689 4.3E-54 T 29-03-2018 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2826 2998 5.9E-52 T 29-03-2018 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 Gene3D G3DSA:3.10.129.10 2094 2214 6.9E-6 T 29-03-2018 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 Gene3D G3DSA:3.10.129.10 7091 7210 2.2E-8 T 29-03-2018 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 Gene3D G3DSA:3.10.129.10 5501 5618 5.4E-7 T 29-03-2018 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 ProSitePatterns PS00455 Putative AMP-binding domain signature. 167 178 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 Gene3D G3DSA:1.10.1200.10 7761 7862 2.4E-18 T 29-03-2018 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 6428 6444 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 SUPERFAMILY SSF52151 5351 5431 6.02E-57 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 SUPERFAMILY SSF52151 5179 5294 6.02E-57 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4610 4625 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4674 4919 1.2E-86 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1247 1490 2.9E-86 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3177 3422 1.2E-84 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 6270 6515 9.8E-85 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 Pfam PF13193 AMP-binding enzyme C-terminal domain 424 497 3.4E-13 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 SUPERFAMILY SSF55048 1876 1933 1.44E-9 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 Gene3D G3DSA:3.40.366.10 5337 5445 4.1E-14 T 29-03-2018 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 Gene3D G3DSA:3.40.366.10 1748 1885 4.2E-40 T 29-03-2018 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 Gene3D G3DSA:3.40.366.10 3840 3949 1.9E-13 T 29-03-2018 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 Gene3D G3DSA:3.30.70.250 1886 1927 1.2E-12 T 29-03-2018 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 SUPERFAMILY SSF53901 1243 1603 6.75E-100 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 SUPERFAMILY SSF51735 738 915 1.47E-36 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 Gene3D G3DSA:3.40.47.10 3437 3596 5.7E-61 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 Gene3D G3DSA:3.40.47.10 1505 1664 5.4E-62 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 Gene3D G3DSA:3.40.47.10 6530 6689 1.4E-61 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 Gene3D G3DSA:3.40.47.10 4934 5093 1.0E-60 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 4832 4848 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 Gene3D G3DSA:3.40.50.980 173 323 2.2E-39 T 29-03-2018 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 SMART SM00826 7092 7253 5.5E-78 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 SMART SM00826 3999 4130 1.1E-7 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 SMART SM00826 5500 5661 6.4E-73 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 SMART SM00826 2094 2252 6.6E-73 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 SUPERFAMILY SSF56801 7 509 3.66E-146 T 29-03-2018 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1403 1419 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 Gene3D G3DSA:3.30.300.30 409 514 4.8E-23 T 29-03-2018 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 SUPERFAMILY SSF51735 7363 7503 2.2E-14 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 Pfam PF00501 AMP-binding enzyme 16 414 1.9E-101 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 SUPERFAMILY SSF51735 7513 7758 9.92E-43 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 SUPERFAMILY SSF51735 4324 4554 1.09E-42 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 SUPERFAMILY SSF51735 2613 2751 1.35E-36 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 SUPERFAMILY SSF51735 4147 4311 2.83E-12 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 SUPERFAMILY SSF47336 7776 7862 5.23E-20 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 SUPERFAMILY SSF47336 6173 6285 1.27E-23 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 SUPERFAMILY SSF55048 3796 3845 1.23E-7 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 SUPERFAMILY SSF52151 3854 3934 3.14E-57 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 SUPERFAMILY SSF52151 3682 3797 3.14E-57 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 SUPERFAMILY SSF51735 948 1083 6.37E-7 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 Pfam PF00698 Acyl transferase domain 1753 2051 7.6E-62 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 Pfam PF00698 Acyl transferase domain 6777 7022 1.2E-39 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 Pfam PF00698 Acyl transferase domain 5181 5426 5.8E-42 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 Pfam PF00698 Acyl transferase domain 3684 3930 4.4E-41 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 SUPERFAMILY SSF47336 3080 3191 2.22E-22 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 Gene3D G3DSA:2.30.38.10 324 407 4.5E-25 T 29-03-2018 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3112 3127 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 658 713 1.4E-4 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 3335 3351 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 SUPERFAMILY SSF52151 6775 6890 1.75E-56 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 SUPERFAMILY SSF52151 6947 7027 1.75E-56 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 Pfam PF00550 Phosphopantetheine attachment site 4586 4650 1.4E-9 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 Pfam PF00550 Phosphopantetheine attachment site 7785 7851 9.5E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 Pfam PF00550 Phosphopantetheine attachment site 3088 3152 2.9E-9 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 Pfam PF00550 Phosphopantetheine attachment site 1158 1222 8.9E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 Pfam PF00550 Phosphopantetheine attachment site 6180 6245 2.0E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 SUPERFAMILY SSF51735 5915 6142 8.68E-40 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 Pfam PF08659 KR domain 4328 4499 2.8E-56 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 Pfam PF08659 KR domain 5919 6090 1.2E-54 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 Pfam PF08659 KR domain 7516 7688 6.5E-55 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 Pfam PF08659 KR domain 2826 2997 3.1E-54 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 Gene3D G3DSA:3.40.47.10 4673 4931 3.5E-81 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 Gene3D G3DSA:3.40.47.10 1246 1502 5.9E-77 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 Gene3D G3DSA:3.40.47.10 6269 6527 1.2E-81 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 Gene3D G3DSA:3.40.47.10 3176 3434 7.0E-80 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 SMART SM01294 7784 7851 7.7E-6 T 29-03-2018 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 SMART SM01294 4584 4651 2.3E-5 T 29-03-2018 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 SMART SM01294 3086 3153 1.0E-4 T 29-03-2018 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 SMART SM01294 6179 6246 4.7E-6 T 29-03-2018 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 Pfam PF14765 Polyketide synthase dehydratase 5500 5767 3.0E-51 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 Pfam PF14765 Polyketide synthase dehydratase 7092 7356 9.7E-52 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 Pfam PF14765 Polyketide synthase dehydratase 2094 2359 2.0E-52 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 Gene3D G3DSA:3.40.50.980 7 172 6.5E-42 T 29-03-2018 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 ProSitePatterns PS00012 Phosphopantetheine attachment site. 7810 7825 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 Gene3D G3DSA:3.90.180.10 613 947 4.1E-60 T 29-03-2018 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 Gene3D G3DSA:3.90.180.10 2494 2818 1.4E-59 T 29-03-2018 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 SUPERFAMILY SSF55048 5293 5342 1.14E-7 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 SMART SM00829 2515 2816 9.0E-171 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 SMART SM00829 639 944 5.6E-160 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 SUPERFAMILY SSF50129 2522 2649 7.08E-25 T 29-03-2018 IPR011032 GroES-like SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 5183 5449 9.7E-91 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 6779 7045 9.3E-89 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1755 2036 2.0E-84 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 3686 3952 6.4E-91 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 6523 6638 6.8E-43 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 3430 3545 8.5E-43 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 4927 5042 1.0E-41 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1499 1613 3.6E-43 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 ProSitePatterns PS00012 Phosphopantetheine attachment site. 6205 6220 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 SUPERFAMILY SSF53901 4670 5039 3.17E-101 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1183 1198 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 SMART SM00825 Beta-ketoacyl synthase 4676 5095 5.4E-212 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 SMART SM00825 Beta-ketoacyl synthase 3179 3598 7.6E-210 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 SMART SM00825 Beta-ketoacyl synthase 6272 6691 2.5E-211 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 SMART SM00825 Beta-ketoacyl synthase 1249 1666 2.8E-212 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 SUPERFAMILY SSF52151 1937 2026 2.62E-57 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 SUPERFAMILY SSF52151 1751 1877 2.62E-57 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 SUPERFAMILY SSF47336 1151 1262 1.44E-21 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 Gene3D G3DSA:3.40.366.10 3676 3839 9.7E-48 T 29-03-2018 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 Gene3D G3DSA:3.40.366.10 6936 7048 3.1E-13 T 29-03-2018 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 Gene3D G3DSA:3.40.366.10 6769 6935 6.9E-47 T 29-03-2018 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 Gene3D G3DSA:3.40.366.10 5173 5336 3.9E-47 T 29-03-2018 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 Gene3D G3DSA:1.10.1200.10 6170 6268 1.1E-18 T 29-03-2018 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 Gene3D G3DSA:1.10.1200.10 1149 1245 7.5E-17 T 29-03-2018 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 Gene3D G3DSA:1.10.1200.10 4575 4672 5.6E-17 T 29-03-2018 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 Gene3D G3DSA:1.10.1200.10 3077 3175 1.4E-18 T 29-03-2018 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 Gene3D G3DSA:3.40.50.720 953 1142 7.2E-5 T 29-03-2018 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 Pfam PF13602 Zinc-binding dehydrogenase 810 944 6.4E-21 T 29-03-2018 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 Pfam PF13602 Zinc-binding dehydrogenase 2686 2816 2.3E-19 T 29-03-2018 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 SUPERFAMILY SSF51735 5707 5902 3.5E-14 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 SUPERFAMILY SSF53901 6266 6635 3.17E-104 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 SUPERFAMILY SSF47336 4578 4689 1.83E-20 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 3548 3666 4.8E-14 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1616 1734 1.6E-15 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 6641 6759 1.8E-13 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 5045 5163 9.6E-14 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 SMART SM00823 Phosphopantetheine attachment site 3085 3157 6.2E-29 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 SMART SM00823 Phosphopantetheine attachment site 4583 4655 6.7E-26 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 SMART SM00823 Phosphopantetheine attachment site 6178 6250 4.4E-29 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 SMART SM00823 Phosphopantetheine attachment site 1156 1228 1.5E-21 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 SMART SM00823 Phosphopantetheine attachment site 7783 7855 7.4E-27 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 SUPERFAMILY SSF51735 2333 2494 1.14E-12 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS42020 b6a22dd312efe9839f1a3ad7191c5385 7934 SUPERFAMILY SSF53901 3173 3536 4.76E-101 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS12480 7cc9c45e776b526da3b130d84ef8aa9b 435 Pfam PF13416 Bacterial extracellular solute-binding protein 57 371 1.0E-37 T 29-03-2018 SMALA_RS12480 7cc9c45e776b526da3b130d84ef8aa9b 435 SUPERFAMILY SSF53850 27 432 1.68E-72 T 29-03-2018 SMALA_RS12480 7cc9c45e776b526da3b130d84ef8aa9b 435 Gene3D G3DSA:3.40.190.10 170 396 4.0E-41 T 29-03-2018 SMALA_RS12480 7cc9c45e776b526da3b130d84ef8aa9b 435 Gene3D G3DSA:3.40.190.10 36 169 5.8E-24 T 29-03-2018 SMALA_RS40170 cdbb68b6c831602e286b8c6f4301c333 829 Gene3D G3DSA:2.60.420.10 729 829 1.3E-25 T 29-03-2018 SMALA_RS40170 cdbb68b6c831602e286b8c6f4301c333 829 Pfam PF17390 Bacterial alpha-L-rhamnosidase C-terminal domain 728 800 1.6E-20 T 29-03-2018 IPR035398 Alpha-L-rhamnosidase C-terminal domain SMALA_RS40170 cdbb68b6c831602e286b8c6f4301c333 829 Pfam PF17389 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain 390 724 1.4E-73 T 29-03-2018 IPR035396 Alpha-L-rhamnosidase, six-hairpin glycosidase domain SMALA_RS40170 cdbb68b6c831602e286b8c6f4301c333 829 Gene3D G3DSA:2.60.120.260 267 387 3.2E-42 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS40170 cdbb68b6c831602e286b8c6f4301c333 829 Gene3D G3DSA:1.50.10.10 451 728 4.4E-29 T 29-03-2018 SMALA_RS40170 cdbb68b6c831602e286b8c6f4301c333 829 Gene3D G3DSA:1.50.10.10 388 433 0.0018 T 29-03-2018 SMALA_RS40170 cdbb68b6c831602e286b8c6f4301c333 829 Pfam PF08531 Alpha-L-rhamnosidase N-terminal domain 108 274 1.5E-53 T 29-03-2018 IPR013737 Bacterial alpha-L-rhamnosidase N-terminal SMALA_RS40170 cdbb68b6c831602e286b8c6f4301c333 829 SUPERFAMILY SSF48208 386 795 1.29E-39 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 SMALA_RS40170 cdbb68b6c831602e286b8c6f4301c333 829 Gene3D G3DSA:2.60.120.260 76 265 3.5E-56 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS40170 cdbb68b6c831602e286b8c6f4301c333 829 Pfam PF05592 Bacterial alpha-L-rhamnosidase concanavalin-like domain 284 385 1.2E-28 T 29-03-2018 IPR008902 Alpha-L-rhamnosidase, concanavalin-like domain SMALA_RS40170 cdbb68b6c831602e286b8c6f4301c333 829 Gene3D G3DSA:2.60.40.10 1 75 1.3E-16 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS40170 cdbb68b6c831602e286b8c6f4301c333 829 PIRSF PIRSF010631 1 829 6.9E-250 T 29-03-2018 IPR016007 Alpha-L-rhamnosidase SMALA_RS10160 87f9b150d4eb9d9cb5412663969a5c70 313 Gene3D G3DSA:3.30.2350.10 84 312 4.2E-64 T 29-03-2018 SMALA_RS10160 87f9b150d4eb9d9cb5412663969a5c70 313 SUPERFAMILY SSF55174 19 69 2.16E-6 T 29-03-2018 SMALA_RS10160 87f9b150d4eb9d9cb5412663969a5c70 313 Pfam PF01479 S4 domain 19 62 4.2E-5 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SMALA_RS10160 87f9b150d4eb9d9cb5412663969a5c70 313 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 139 153 - T 29-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 SMALA_RS10160 87f9b150d4eb9d9cb5412663969a5c70 313 Pfam PF00849 RNA pseudouridylate synthase 93 247 4.7E-32 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 SMALA_RS10160 87f9b150d4eb9d9cb5412663969a5c70 313 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 17 306 1.7E-85 T 29-03-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 SMALA_RS10160 87f9b150d4eb9d9cb5412663969a5c70 313 SUPERFAMILY SSF55120 82 309 1.19E-69 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 SMALA_RS10160 87f9b150d4eb9d9cb5412663969a5c70 313 Gene3D G3DSA:3.10.290.10 7 75 5.2E-13 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SMALA_RS02445 a47f49be0ffcc85cff8b53c4b2e0cbb4 799 Gene3D G3DSA:4.10.1090.10 722 758 2.9E-11 T 29-03-2018 SMALA_RS02445 a47f49be0ffcc85cff8b53c4b2e0cbb4 799 Pfam PF14200 Ricin-type beta-trefoil lectin domain-like 702 786 1.2E-18 T 29-03-2018 IPR000772 Ricin B, lectin domain SMALA_RS02445 a47f49be0ffcc85cff8b53c4b2e0cbb4 799 Gene3D G3DSA:1.50.10.10 57 392 2.8E-24 T 29-03-2018 SMALA_RS02445 a47f49be0ffcc85cff8b53c4b2e0cbb4 799 Gene3D G3DSA:2.80.10.50 759 799 5.6E-12 T 29-03-2018 SMALA_RS02445 a47f49be0ffcc85cff8b53c4b2e0cbb4 799 SUPERFAMILY SSF50370 665 798 1.62E-37 T 29-03-2018 IPR000772 Ricin B, lectin domain SMALA_RS02445 a47f49be0ffcc85cff8b53c4b2e0cbb4 799 Gene3D G3DSA:2.80.10.50 601 721 1.1E-10 T 29-03-2018 SMALA_RS02445 a47f49be0ffcc85cff8b53c4b2e0cbb4 799 Pfam PF07944 Beta-L-arabinofuranosidase, GH127 99 538 1.7E-70 T 29-03-2018 IPR012878 Beta-L-arabinofuranosidase, GH127 KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18 SMALA_RS02445 a47f49be0ffcc85cff8b53c4b2e0cbb4 799 SUPERFAMILY SSF48208 82 364 9.64E-17 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 SMALA_RS33760 a37d0a54df6eae8151b81c6ebe78ee38 426 SUPERFAMILY SSF46785 12 75 1.33E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS33760 a37d0a54df6eae8151b81c6ebe78ee38 426 Gene3D G3DSA:3.30.420.40 76 211 5.6E-30 T 29-03-2018 SMALA_RS33760 a37d0a54df6eae8151b81c6ebe78ee38 426 Pfam PF00480 ROK family 86 414 1.2E-47 T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 SMALA_RS33760 a37d0a54df6eae8151b81c6ebe78ee38 426 Gene3D G3DSA:3.30.420.40 212 425 8.1E-46 T 29-03-2018 SMALA_RS33760 a37d0a54df6eae8151b81c6ebe78ee38 426 Gene3D G3DSA:1.10.10.10 17 75 1.1E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS33760 a37d0a54df6eae8151b81c6ebe78ee38 426 SUPERFAMILY SSF53067 320 419 1.02E-49 T 29-03-2018 SMALA_RS33760 a37d0a54df6eae8151b81c6ebe78ee38 426 SUPERFAMILY SSF53067 83 293 1.02E-49 T 29-03-2018 SMALA_RS33760 a37d0a54df6eae8151b81c6ebe78ee38 426 ProSitePatterns PS01125 ROK family signature. 221 248 - T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 SMALA_RS40665 8d8f254be54632507e48f7594c63e4ee 219 SUPERFAMILY SSF54427 13 142 1.39E-21 T 29-03-2018 IPR032710 NTF2-like domain SMALA_RS40665 8d8f254be54632507e48f7594c63e4ee 219 Gene3D G3DSA:3.10.450.50 10 136 6.6E-15 T 29-03-2018 SMALA_RS40665 8d8f254be54632507e48f7594c63e4ee 219 Pfam PF13577 SnoaL-like domain 16 132 7.0E-10 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain SMALA_RS12535 0646a9b257bfb1f581f56c0fa07f053e 255 Pfam PF12391 Protocatechuate 3,4-dioxygenase beta subunit N terminal 26 55 9.0E-14 T 29-03-2018 IPR024756 Protocatechuate 3,4-dioxygenase beta subunit, N-terminal KEGG: 00362+1.13.11.3|KEGG: 00624+1.13.11.3 SMALA_RS12535 0646a9b257bfb1f581f56c0fa07f053e 255 ProSitePatterns PS00083 Intradiol ring-cleavage dioxygenases signature. 96 124 - T 29-03-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 SMALA_RS12535 0646a9b257bfb1f581f56c0fa07f053e 255 SUPERFAMILY SSF49482 31 252 3.01E-67 T 29-03-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 SMALA_RS12535 0646a9b257bfb1f581f56c0fa07f053e 255 TIGRFAM TIGR02422 protocat_beta: protocatechuate 3,4-dioxygenase, beta subunit 32 253 2.3E-109 T 29-03-2018 IPR012785 Protocatechuate 3,4-dioxygenase, beta subunit GO:0005506|GO:0018578|GO:0019619|GO:0055114 KEGG: 00362+1.13.11.3|KEGG: 00624+1.13.11.3 SMALA_RS12535 0646a9b257bfb1f581f56c0fa07f053e 255 Pfam PF00775 Dioxygenase 66 245 7.8E-57 T 29-03-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 SMALA_RS12535 0646a9b257bfb1f581f56c0fa07f053e 255 Gene3D G3DSA:2.60.130.10 17 253 5.4E-64 T 29-03-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 SMALA_RS13445 4d1e3b1f7164cccd9ab4b3641c0390fa 420 Pfam PF02056 Family 4 glycosyl hydrolase 2 179 2.8E-44 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SMALA_RS13445 4d1e3b1f7164cccd9ab4b3641c0390fa 420 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 190 396 3.0E-44 T 29-03-2018 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 SMALA_RS13445 4d1e3b1f7164cccd9ab4b3641c0390fa 420 Gene3D G3DSA:3.90.110.10 155 420 1.1E-102 T 29-03-2018 SMALA_RS13445 4d1e3b1f7164cccd9ab4b3641c0390fa 420 SUPERFAMILY SSF56327 165 417 2.88E-67 T 29-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 SMALA_RS13445 4d1e3b1f7164cccd9ab4b3641c0390fa 420 PRINTS PR00732 Glycosyl hydrolase family 4 signature 185 197 4.8E-34 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SMALA_RS13445 4d1e3b1f7164cccd9ab4b3641c0390fa 420 PRINTS PR00732 Glycosyl hydrolase family 4 signature 2 17 4.8E-34 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SMALA_RS13445 4d1e3b1f7164cccd9ab4b3641c0390fa 420 PRINTS PR00732 Glycosyl hydrolase family 4 signature 92 105 4.8E-34 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SMALA_RS13445 4d1e3b1f7164cccd9ab4b3641c0390fa 420 PRINTS PR00732 Glycosyl hydrolase family 4 signature 106 126 4.8E-34 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SMALA_RS13445 4d1e3b1f7164cccd9ab4b3641c0390fa 420 PRINTS PR00732 Glycosyl hydrolase family 4 signature 135 152 4.8E-34 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SMALA_RS13445 4d1e3b1f7164cccd9ab4b3641c0390fa 420 PRINTS PR00732 Glycosyl hydrolase family 4 signature 71 87 4.8E-34 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SMALA_RS13445 4d1e3b1f7164cccd9ab4b3641c0390fa 420 Gene3D G3DSA:3.40.50.720 1 154 1.4E-27 T 29-03-2018 SMALA_RS13445 4d1e3b1f7164cccd9ab4b3641c0390fa 420 SUPERFAMILY SSF51735 1 156 9.58E-43 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS06285 286d2fd8cffff64c6701ea90d2bb1cb1 915 Pfam PF00690 Cation transporter/ATPase, N-terminus 66 126 2.0E-13 T 29-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 SMALA_RS06285 286d2fd8cffff64c6701ea90d2bb1cb1 915 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 138 411 1.2E-27 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMALA_RS06285 286d2fd8cffff64c6701ea90d2bb1cb1 915 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 615 745 1.0E-19 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMALA_RS06285 286d2fd8cffff64c6701ea90d2bb1cb1 915 Gene3D G3DSA:2.70.150.10 68 288 9.0E-34 T 29-03-2018 SMALA_RS06285 286d2fd8cffff64c6701ea90d2bb1cb1 915 Gene3D G3DSA:3.40.1110.10 340 555 1.1E-27 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 SMALA_RS06285 286d2fd8cffff64c6701ea90d2bb1cb1 915 SUPERFAMILY SSF81660 393 554 7.33E-20 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 SMALA_RS06285 286d2fd8cffff64c6701ea90d2bb1cb1 915 SUPERFAMILY SSF56784 385 405 7.64E-31 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS06285 286d2fd8cffff64c6701ea90d2bb1cb1 915 SUPERFAMILY SSF56784 504 755 7.64E-31 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS06285 286d2fd8cffff64c6701ea90d2bb1cb1 915 Gene3D G3DSA:1.20.1110.10 587 909 1.2E-37 T 29-03-2018 SMALA_RS06285 286d2fd8cffff64c6701ea90d2bb1cb1 915 SMART SM00831 61 131 1.6E-12 T 29-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 SMALA_RS06285 286d2fd8cffff64c6701ea90d2bb1cb1 915 Pfam PF00689 Cation transporting ATPase, C-terminus 739 889 3.3E-7 T 29-03-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 SMALA_RS06285 286d2fd8cffff64c6701ea90d2bb1cb1 915 Pfam PF00702 haloacid dehalogenase-like hydrolase 383 662 1.7E-17 T 29-03-2018 SMALA_RS06285 286d2fd8cffff64c6701ea90d2bb1cb1 915 SUPERFAMILY SSF81653 186 284 4.05E-22 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 SMALA_RS06285 286d2fd8cffff64c6701ea90d2bb1cb1 915 SUPERFAMILY SSF81665 287 381 2.22E-66 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SMALA_RS06285 286d2fd8cffff64c6701ea90d2bb1cb1 915 SUPERFAMILY SSF81665 66 169 2.22E-66 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SMALA_RS06285 286d2fd8cffff64c6701ea90d2bb1cb1 915 SUPERFAMILY SSF81665 705 897 2.22E-66 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SMALA_RS06285 286d2fd8cffff64c6701ea90d2bb1cb1 915 TIGRFAM TIGR01524 ATPase-IIIB_Mg: magnesium-translocating P-type ATPase 66 906 7.1E-207 T 29-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 SMALA_RS06285 286d2fd8cffff64c6701ea90d2bb1cb1 915 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 389 395 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 SMALA_RS06285 286d2fd8cffff64c6701ea90d2bb1cb1 915 Pfam PF00122 E1-E2 ATPase 167 365 3.5E-34 T 29-03-2018 SMALA_RS06285 286d2fd8cffff64c6701ea90d2bb1cb1 915 PRINTS PR01836 Magnesium-transporting ATPase signature 316 335 6.6E-32 T 29-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 SMALA_RS06285 286d2fd8cffff64c6701ea90d2bb1cb1 915 PRINTS PR01836 Magnesium-transporting ATPase signature 784 800 6.6E-32 T 29-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 SMALA_RS06285 286d2fd8cffff64c6701ea90d2bb1cb1 915 PRINTS PR01836 Magnesium-transporting ATPase signature 299 315 6.6E-32 T 29-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 SMALA_RS06285 286d2fd8cffff64c6701ea90d2bb1cb1 915 PRINTS PR01836 Magnesium-transporting ATPase signature 819 840 6.6E-32 T 29-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 SMALA_RS06285 286d2fd8cffff64c6701ea90d2bb1cb1 915 PRINTS PR01836 Magnesium-transporting ATPase signature 714 729 6.6E-32 T 29-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 SMALA_RS06285 286d2fd8cffff64c6701ea90d2bb1cb1 915 PRINTS PR01836 Magnesium-transporting ATPase signature 867 888 6.6E-32 T 29-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 SMALA_RS06285 286d2fd8cffff64c6701ea90d2bb1cb1 915 PRINTS PR01836 Magnesium-transporting ATPase signature 732 743 6.6E-32 T 29-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 SMALA_RS39720 2c9a7f73f9c587d70626c3552c3492a0 497 SUPERFAMILY SSF103473 15 201 1.23E-41 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS39720 2c9a7f73f9c587d70626c3552c3492a0 497 Gene3D G3DSA:1.20.1250.20 266 484 5.1E-28 T 29-03-2018 SMALA_RS39720 2c9a7f73f9c587d70626c3552c3492a0 497 Gene3D G3DSA:1.20.1250.20 18 205 4.7E-33 T 29-03-2018 SMALA_RS39720 2c9a7f73f9c587d70626c3552c3492a0 497 Pfam PF07690 Major Facilitator Superfamily 26 299 3.1E-31 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS39720 2c9a7f73f9c587d70626c3552c3492a0 497 SUPERFAMILY SSF103473 204 472 2.22E-25 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS25400 aa6f7e8ab68e4e351ffa6f3535e8e608 410 SMART SM00387 292 403 1.4E-24 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS25400 aa6f7e8ab68e4e351ffa6f3535e8e608 410 SUPERFAMILY SSF158472 130 180 8.89E-6 T 29-03-2018 SMALA_RS25400 aa6f7e8ab68e4e351ffa6f3535e8e608 410 Gene3D G3DSA:3.30.565.10 253 409 6.2E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS25400 aa6f7e8ab68e4e351ffa6f3535e8e608 410 Pfam PF00672 HAMP domain 130 179 8.1E-7 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMALA_RS25400 aa6f7e8ab68e4e351ffa6f3535e8e608 410 SUPERFAMILY SSF47384 166 244 5.89E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS25400 aa6f7e8ab68e4e351ffa6f3535e8e608 410 Gene3D G3DSA:1.10.287.130 173 244 9.1E-10 T 29-03-2018 SMALA_RS25400 aa6f7e8ab68e4e351ffa6f3535e8e608 410 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 292 400 1.6E-14 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS25400 aa6f7e8ab68e4e351ffa6f3535e8e608 410 SUPERFAMILY SSF55874 246 399 2.88E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS25400 aa6f7e8ab68e4e351ffa6f3535e8e608 410 SMART SM00388 183 249 2.1E-10 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS25400 aa6f7e8ab68e4e351ffa6f3535e8e608 410 Pfam PF00512 His Kinase A (phospho-acceptor) domain 183 244 4.9E-8 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS25400 aa6f7e8ab68e4e351ffa6f3535e8e608 410 SMART SM00304 129 182 3.6E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMALA_RS31015 abbf811e99f45fd296cceeea7548f77c 184 SUPERFAMILY SSF52317 1 175 2.87E-41 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS31015 abbf811e99f45fd296cceeea7548f77c 184 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 6 173 1.1E-45 T 29-03-2018 IPR006286 Peptidase C56, PfpI SMALA_RS31015 abbf811e99f45fd296cceeea7548f77c 184 Gene3D G3DSA:3.40.50.880 1 183 2.7E-39 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS31015 abbf811e99f45fd296cceeea7548f77c 184 Pfam PF01965 DJ-1/PfpI family 1 174 2.9E-48 T 29-03-2018 IPR002818 DJ-1/PfpI SMALA_RS39265 7a423d7dab4f5ad5550f13a6309eef8d 503 Pfam PF00206 Lyase 103 300 4.4E-25 T 29-03-2018 IPR022761 Fumarate lyase, N-terminal SMALA_RS39265 7a423d7dab4f5ad5550f13a6309eef8d 503 PRINTS PR00145 Argininosuccinate lyase family signature 275 291 3.4E-16 T 29-03-2018 SMALA_RS39265 7a423d7dab4f5ad5550f13a6309eef8d 503 PRINTS PR00145 Argininosuccinate lyase family signature 101 123 3.4E-16 T 29-03-2018 SMALA_RS39265 7a423d7dab4f5ad5550f13a6309eef8d 503 PRINTS PR00145 Argininosuccinate lyase family signature 193 209 3.4E-16 T 29-03-2018 SMALA_RS39265 7a423d7dab4f5ad5550f13a6309eef8d 503 PRINTS PR00145 Argininosuccinate lyase family signature 231 255 3.4E-16 T 29-03-2018 SMALA_RS39265 7a423d7dab4f5ad5550f13a6309eef8d 503 PRINTS PR00145 Argininosuccinate lyase family signature 142 162 3.4E-16 T 29-03-2018 SMALA_RS39265 7a423d7dab4f5ad5550f13a6309eef8d 503 SUPERFAMILY SSF48557 30 409 3.93E-63 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 SMALA_RS39265 7a423d7dab4f5ad5550f13a6309eef8d 503 Gene3D G3DSA:1.20.200.10 106 422 1.0E-65 T 29-03-2018 SMALA_RS39265 7a423d7dab4f5ad5550f13a6309eef8d 503 PRINTS PR00149 Fumarate lyase superfamily signature 231 258 1.4E-6 T 29-03-2018 IPR000362 Fumarate lyase family SMALA_RS39265 7a423d7dab4f5ad5550f13a6309eef8d 503 PRINTS PR00149 Fumarate lyase superfamily signature 102 120 1.4E-6 T 29-03-2018 IPR000362 Fumarate lyase family SMALA_RS39265 7a423d7dab4f5ad5550f13a6309eef8d 503 PRINTS PR00149 Fumarate lyase superfamily signature 275 291 1.4E-6 T 29-03-2018 IPR000362 Fumarate lyase family SMALA_RS39265 7a423d7dab4f5ad5550f13a6309eef8d 503 PRINTS PR00149 Fumarate lyase superfamily signature 147 165 1.4E-6 T 29-03-2018 IPR000362 Fumarate lyase family SMALA_RS01880 81b274fcbf9961b463eae3e96ae3914c 259 Gene3D G3DSA:3.50.30.40 32 207 9.5E-52 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein SMALA_RS01880 81b274fcbf9961b463eae3e96ae3914c 259 SUPERFAMILY SSF89562 36 197 2.49E-47 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein SMALA_RS01880 81b274fcbf9961b463eae3e96ae3914c 259 Pfam PF03737 Aldolase/RraA 40 186 6.0E-40 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein SMALA_RS26395 c188d7df24f8ee3a157e8e5acefcd85a 312 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 222 310 9.4E-26 T 29-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SMALA_RS26395 c188d7df24f8ee3a157e8e5acefcd85a 312 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 2 311 57.343 T 29-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SMALA_RS26395 c188d7df24f8ee3a157e8e5acefcd85a 312 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 5 310 6.3E-88 T 29-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SMALA_RS26395 c188d7df24f8ee3a157e8e5acefcd85a 312 Gene3D G3DSA:3.40.47.10 3 203 2.5E-48 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS26395 c188d7df24f8ee3a157e8e5acefcd85a 312 Gene3D G3DSA:3.40.47.10 204 312 4.7E-21 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS26395 c188d7df24f8ee3a157e8e5acefcd85a 312 SUPERFAMILY SSF53901 6 310 4.53E-56 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS26395 c188d7df24f8ee3a157e8e5acefcd85a 312 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 107 181 6.9E-26 T 29-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SMALA_RS25350 48cabaf8253e55166a71eeb622c2d3e5 402 Gene3D G3DSA:1.25.40.10 130 395 1.5E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS25350 48cabaf8253e55166a71eeb622c2d3e5 402 SMART SM00530 4 60 7.3E-4 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS25350 48cabaf8253e55166a71eeb622c2d3e5 402 Gene3D G3DSA:1.10.260.40 1 66 6.1E-10 T 29-03-2018 SMALA_RS25350 48cabaf8253e55166a71eeb622c2d3e5 402 Pfam PF13560 Helix-turn-helix domain 2 57 4.1E-10 T 29-03-2018 SMALA_RS25350 48cabaf8253e55166a71eeb622c2d3e5 402 SUPERFAMILY SSF48452 136 356 2.91E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS25350 48cabaf8253e55166a71eeb622c2d3e5 402 SUPERFAMILY SSF47413 2 57 7.7E-9 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS31265 7549aa1cef3ce966a77755f2942831f5 152 SUPERFAMILY SSF54593 7 152 8.8E-14 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS31265 7549aa1cef3ce966a77755f2942831f5 152 Gene3D G3DSA:3.10.180.10 5 152 9.9E-22 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS09555 2f966b2788a3e9876ffb9fec143a5200 412 Gene3D G3DSA:1.20.1250.20 217 410 1.0E-21 T 29-03-2018 SMALA_RS09555 2f966b2788a3e9876ffb9fec143a5200 412 SUPERFAMILY SSF103473 24 404 7.59E-43 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS09555 2f966b2788a3e9876ffb9fec143a5200 412 Gene3D G3DSA:1.20.1250.20 18 212 6.2E-11 T 29-03-2018 SMALA_RS09555 2f966b2788a3e9876ffb9fec143a5200 412 Pfam PF05977 Transmembrane secretion effector 21 402 1.2E-24 T 29-03-2018 IPR010290 Transmembrane secretion effector SMALA_RS39215 f306cdd2b6d581960f3b0554f6b5fca2 1074 SUPERFAMILY SSF56801 111 677 4.06E-138 T 29-03-2018 SMALA_RS39215 f306cdd2b6d581960f3b0554f6b5fca2 1074 Gene3D G3DSA:3.40.50.980 141 296 2.5E-43 T 29-03-2018 SMALA_RS39215 f306cdd2b6d581960f3b0554f6b5fca2 1074 Gene3D G3DSA:3.40.50.980 297 444 6.3E-38 T 29-03-2018 SMALA_RS39215 f306cdd2b6d581960f3b0554f6b5fca2 1074 Gene3D G3DSA:3.60.130.10 755 1056 1.3E-60 T 29-03-2018 SMALA_RS39215 f306cdd2b6d581960f3b0554f6b5fca2 1074 SUPERFAMILY SSF47336 661 753 1.96E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS39215 f306cdd2b6d581960f3b0554f6b5fca2 1074 Pfam PF00550 Phosphopantetheine attachment site 665 727 2.3E-9 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS39215 f306cdd2b6d581960f3b0554f6b5fca2 1074 Pfam PF00501 AMP-binding enzyme 148 549 1.7E-89 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS39215 f306cdd2b6d581960f3b0554f6b5fca2 1074 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 769 1052 1.9E-39 T 29-03-2018 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 SMALA_RS39215 f306cdd2b6d581960f3b0554f6b5fca2 1074 ProSitePatterns PS00455 Putative AMP-binding domain signature. 292 303 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS39215 f306cdd2b6d581960f3b0554f6b5fca2 1074 Gene3D G3DSA:2.30.38.10 461 542 2.4E-18 T 29-03-2018 SMALA_RS39215 f306cdd2b6d581960f3b0554f6b5fca2 1074 Gene3D G3DSA:3.30.300.30 545 669 3.1E-27 T 29-03-2018 SMALA_RS39215 f306cdd2b6d581960f3b0554f6b5fca2 1074 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 169 574 5.8E-113 T 29-03-2018 IPR010071 Amino acid adenylation domain SMALA_RS39215 f306cdd2b6d581960f3b0554f6b5fca2 1074 Pfam PF13193 AMP-binding enzyme C-terminal domain 558 630 1.6E-5 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS39215 f306cdd2b6d581960f3b0554f6b5fca2 1074 SUPERFAMILY SSF51197 766 1055 5.95E-67 T 29-03-2018 SMALA_RS39215 f306cdd2b6d581960f3b0554f6b5fca2 1074 Gene3D G3DSA:1.10.1200.10 670 754 1.9E-17 T 29-03-2018 SMALA_RS27645 8f0de5205c706c4cb4a5f53f4975ba09 740 SUPERFAMILY SSF56091 11 327 1.06E-112 T 29-03-2018 SMALA_RS27645 8f0de5205c706c4cb4a5f53f4975ba09 740 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 331 407 5.2E-28 T 29-03-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 SMALA_RS27645 8f0de5205c706c4cb4a5f53f4975ba09 740 Gene3D G3DSA:1.10.150.20 442 550 4.2E-18 T 29-03-2018 SMALA_RS27645 8f0de5205c706c4cb4a5f53f4975ba09 740 Gene3D G3DSA:1.10.150.20 551 616 7.9E-27 T 29-03-2018 SMALA_RS27645 8f0de5205c706c4cb4a5f53f4975ba09 740 SUPERFAMILY SSF52113 637 714 1.63E-18 T 29-03-2018 IPR001357 BRCT domain SMALA_RS27645 8f0de5205c706c4cb4a5f53f4975ba09 740 Hamap MF_01588 DNA ligase [ligA]. 11 712 51.611 T 29-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 SMALA_RS27645 8f0de5205c706c4cb4a5f53f4975ba09 740 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 416 444 3.1E-8 T 29-03-2018 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 SMALA_RS27645 8f0de5205c706c4cb4a5f53f4975ba09 740 SUPERFAMILY SSF47781 412 505 5.93E-45 T 29-03-2018 IPR010994 RuvA domain 2-like SMALA_RS27645 8f0de5205c706c4cb4a5f53f4975ba09 740 SUPERFAMILY SSF47781 536 628 5.93E-45 T 29-03-2018 IPR010994 RuvA domain 2-like SMALA_RS27645 8f0de5205c706c4cb4a5f53f4975ba09 740 Gene3D G3DSA:3.30.1490.70 247 330 9.8E-25 T 29-03-2018 SMALA_RS27645 8f0de5205c706c4cb4a5f53f4975ba09 740 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 20 500 3.0E-176 T 29-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 SMALA_RS27645 8f0de5205c706c4cb4a5f53f4975ba09 740 Gene3D G3DSA:1.10.287.610 3 75 3.7E-28 T 29-03-2018 SMALA_RS27645 8f0de5205c706c4cb4a5f53f4975ba09 740 Gene3D G3DSA:3.30.470.30 127 246 2.1E-52 T 29-03-2018 SMALA_RS27645 8f0de5205c706c4cb4a5f53f4975ba09 740 SMART SM00292 638 715 5.6E-12 T 29-03-2018 IPR001357 BRCT domain SMALA_RS27645 8f0de5205c706c4cb4a5f53f4975ba09 740 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 340 355 - T 29-03-2018 IPR033136 NAD-dependent DNA ligase, conserved site SMALA_RS27645 8f0de5205c706c4cb4a5f53f4975ba09 740 PIRSF PIRSF001604 4 716 1.9E-239 T 29-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 SMALA_RS27645 8f0de5205c706c4cb4a5f53f4975ba09 740 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 638 706 3.5E-13 T 29-03-2018 IPR001357 BRCT domain SMALA_RS27645 8f0de5205c706c4cb4a5f53f4975ba09 740 SUPERFAMILY SSF50249 327 409 2.74E-24 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMALA_RS27645 8f0de5205c706c4cb4a5f53f4975ba09 740 Pfam PF12826 Helix-hairpin-helix motif 555 618 1.7E-21 T 29-03-2018 SMALA_RS27645 8f0de5205c706c4cb4a5f53f4975ba09 740 Gene3D G3DSA:2.40.50.140 331 398 1.1E-25 T 29-03-2018 SMALA_RS27645 8f0de5205c706c4cb4a5f53f4975ba09 740 Gene3D G3DSA:3.40.50.10190 617 715 3.7E-20 T 29-03-2018 IPR001357 BRCT domain SMALA_RS27645 8f0de5205c706c4cb4a5f53f4975ba09 740 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 12 327 1.6E-122 T 29-03-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 SMALA_RS27645 8f0de5205c706c4cb4a5f53f4975ba09 740 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 123 152 - T 29-03-2018 IPR018239 NAD-dependent DNA ligase, active site SMALA_RS27645 8f0de5205c706c4cb4a5f53f4975ba09 740 SMART SM00532 12 458 4.7E-258 T 29-03-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 SMALA_RS25830 0a94486f3ecc7a8695a270260676685f 156 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 21 40 3.0E-10 T 29-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 SMALA_RS25830 0a94486f3ecc7a8695a270260676685f 156 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 1 21 3.0E-10 T 29-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 SMALA_RS25830 0a94486f3ecc7a8695a270260676685f 156 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 40 58 3.0E-10 T 29-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 SMALA_RS25830 0a94486f3ecc7a8695a270260676685f 156 Hamap MF_00237 Sec-independent protein translocase protein TatB [tatB]. 1 147 14.114 T 29-03-2018 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 SMALA_RS25830 0a94486f3ecc7a8695a270260676685f 156 Pfam PF02416 mttA/Hcf106 family 4 33 7.0E-5 T 29-03-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 SMALA_RS16590 96f3cd5ce64afc5f70c2ad30b2ae388f 342 Gene3D G3DSA:3.90.180.10 4 162 4.3E-45 T 29-03-2018 SMALA_RS16590 96f3cd5ce64afc5f70c2ad30b2ae388f 342 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 137 7.0E-28 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS16590 96f3cd5ce64afc5f70c2ad30b2ae388f 342 SUPERFAMILY SSF51735 148 303 5.26E-30 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS16590 96f3cd5ce64afc5f70c2ad30b2ae388f 342 Pfam PF00107 Zinc-binding dehydrogenase 180 303 3.4E-17 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMALA_RS16590 96f3cd5ce64afc5f70c2ad30b2ae388f 342 SUPERFAMILY SSF50129 4 178 2.13E-49 T 29-03-2018 IPR011032 GroES-like SMALA_RS16590 96f3cd5ce64afc5f70c2ad30b2ae388f 342 Gene3D G3DSA:3.40.50.720 163 313 4.0E-23 T 29-03-2018 SMALA_RS16590 96f3cd5ce64afc5f70c2ad30b2ae388f 342 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 SMALA_RS03350 512e916305c2e92113d52b00d407458f 290 Gene3D G3DSA:1.20.1170.10 44 269 7.8E-5 T 29-03-2018 SMALA_RS03350 512e916305c2e92113d52b00d407458f 290 Pfam PF05949 Bacterial protein of unknown function (DUF881) 153 285 6.8E-40 T 29-03-2018 IPR010273 Protein of unknown function DUF881 SMALA_RS16110 9acd61e5f68edf9442cd65eb2ff73422 787 SUPERFAMILY SSF52540 21 303 3.16E-24 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS16110 9acd61e5f68edf9442cd65eb2ff73422 787 Gene3D G3DSA:1.10.150.200 534 577 1.5E-5 T 29-03-2018 SMALA_RS16110 9acd61e5f68edf9442cd65eb2ff73422 787 PRINTS PR00364 Disease resistance protein signature 144 158 1.6E-6 T 29-03-2018 SMALA_RS16110 9acd61e5f68edf9442cd65eb2ff73422 787 PRINTS PR00364 Disease resistance protein signature 232 246 1.6E-6 T 29-03-2018 SMALA_RS16110 9acd61e5f68edf9442cd65eb2ff73422 787 PRINTS PR00364 Disease resistance protein signature 66 81 1.6E-6 T 29-03-2018 SMALA_RS16110 9acd61e5f68edf9442cd65eb2ff73422 787 SUPERFAMILY SSF48452 480 646 1.52E-18 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS16110 9acd61e5f68edf9442cd65eb2ff73422 787 Gene3D G3DSA:1.10.10.10 222 360 1.8E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS16110 9acd61e5f68edf9442cd65eb2ff73422 787 Gene3D G3DSA:1.20.1250.10 578 630 2.7E-8 T 29-03-2018 SMALA_RS16110 9acd61e5f68edf9442cd65eb2ff73422 787 Gene3D G3DSA:1.20.1250.10 692 769 1.3E-5 T 29-03-2018 SMALA_RS16110 9acd61e5f68edf9442cd65eb2ff73422 787 Gene3D G3DSA:3.40.50.300 14 190 2.7E-12 T 29-03-2018 SMALA_RS16110 9acd61e5f68edf9442cd65eb2ff73422 787 SMART SM00028 490 523 310.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS16110 9acd61e5f68edf9442cd65eb2ff73422 787 SMART SM00028 530 563 32.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS16110 9acd61e5f68edf9442cd65eb2ff73422 787 SMART SM00028 570 603 110.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS16110 9acd61e5f68edf9442cd65eb2ff73422 787 SMART SM00028 610 643 30.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS16110 9acd61e5f68edf9442cd65eb2ff73422 787 SMART SM00028 650 683 4.9 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS16110 9acd61e5f68edf9442cd65eb2ff73422 787 SMART SM00028 690 723 0.58 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS16110 9acd61e5f68edf9442cd65eb2ff73422 787 SUPERFAMILY SSF48452 652 765 1.49E-13 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS16110 9acd61e5f68edf9442cd65eb2ff73422 787 Gene3D G3DSA:3.30.70.100 631 691 7.2E-9 T 29-03-2018 SMALA_RS16110 9acd61e5f68edf9442cd65eb2ff73422 787 Gene3D G3DSA:3.30.70.100 460 533 2.1E-8 T 29-03-2018 SMALA_RS16110 9acd61e5f68edf9442cd65eb2ff73422 787 Pfam PF13424 Tetratricopeptide repeat 490 561 4.0E-7 T 29-03-2018 SMALA_RS16110 9acd61e5f68edf9442cd65eb2ff73422 787 Pfam PF13424 Tetratricopeptide repeat 654 721 4.5E-9 T 29-03-2018 SMALA_RS16110 9acd61e5f68edf9442cd65eb2ff73422 787 Pfam PF13424 Tetratricopeptide repeat 570 641 1.4E-8 T 29-03-2018 SMALA_RS14270 8551b10d6e1f8a7a71ac99ac4c7144f8 113 SMART SM00418 7 85 6.2E-11 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS14270 8551b10d6e1f8a7a71ac99ac4c7144f8 113 Pfam PF12840 Helix-turn-helix domain 9 65 4.2E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS14270 8551b10d6e1f8a7a71ac99ac4c7144f8 113 Gene3D G3DSA:1.10.10.10 2 107 1.0E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS14270 8551b10d6e1f8a7a71ac99ac4c7144f8 113 SUPERFAMILY SSF46785 5 98 7.89E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS14270 8551b10d6e1f8a7a71ac99ac4c7144f8 113 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 41 56 2.4E-7 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS14270 8551b10d6e1f8a7a71ac99ac4c7144f8 113 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 56 71 2.4E-7 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS14270 8551b10d6e1f8a7a71ac99ac4c7144f8 113 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 9 24 2.4E-7 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS09525 9fa9275297de2b232aef8075ef3d48a9 692 ProSitePatterns PS00802 Transketolase signature 2. 491 507 - T 29-03-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SMALA_RS09525 9fa9275297de2b232aef8075ef3d48a9 692 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 16 355 2.5E-133 T 29-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SMALA_RS09525 9fa9275297de2b232aef8075ef3d48a9 692 Gene3D G3DSA:3.40.50.920 563 686 5.3E-31 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMALA_RS09525 9fa9275297de2b232aef8075ef3d48a9 692 SUPERFAMILY SSF52518 5 341 1.31E-101 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold SMALA_RS09525 9fa9275297de2b232aef8075ef3d48a9 692 Gene3D G3DSA:3.40.50.970 5 359 9.7E-88 T 29-03-2018 SMALA_RS09525 9fa9275297de2b232aef8075ef3d48a9 692 SUPERFAMILY SSF52518 358 553 2.59E-64 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold SMALA_RS09525 9fa9275297de2b232aef8075ef3d48a9 692 TIGRFAM TIGR00232 tktlase_bact: transketolase 18 685 6.9E-234 T 29-03-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 SMALA_RS09525 9fa9275297de2b232aef8075ef3d48a9 692 ProSitePatterns PS00801 Transketolase signature 1. 24 44 - T 29-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SMALA_RS09525 9fa9275297de2b232aef8075ef3d48a9 692 SUPERFAMILY SSF52922 557 688 3.8E-40 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMALA_RS09525 9fa9275297de2b232aef8075ef3d48a9 692 Pfam PF02780 Transketolase, C-terminal domain 573 679 2.6E-10 T 29-03-2018 IPR033248 Transketolase, C-terminal domain SMALA_RS09525 9fa9275297de2b232aef8075ef3d48a9 692 Gene3D G3DSA:3.40.50.970 360 562 3.0E-52 T 29-03-2018 SMALA_RS09525 9fa9275297de2b232aef8075ef3d48a9 692 SMART SM00861 371 552 4.2E-67 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain SMALA_RS09525 9fa9275297de2b232aef8075ef3d48a9 692 Pfam PF02779 Transketolase, pyrimidine binding domain 370 551 1.3E-45 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain SMALA_RS03460 cefb3d69cc99009d04e6549c8387b114 396 PIRSF PIRSF000429 1 396 2.4E-38 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 SMALA_RS03460 cefb3d69cc99009d04e6549c8387b114 396 SUPERFAMILY SSF53901 276 385 8.64E-21 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS03460 cefb3d69cc99009d04e6549c8387b114 396 Gene3D G3DSA:3.40.47.10 18 217 1.2E-25 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS03460 cefb3d69cc99009d04e6549c8387b114 396 SUPERFAMILY SSF53901 5 229 3.76E-35 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS03460 cefb3d69cc99009d04e6549c8387b114 396 Pfam PF00108 Thiolase, N-terminal domain 22 111 8.2E-8 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 SMALA_RS03460 cefb3d69cc99009d04e6549c8387b114 396 Gene3D G3DSA:3.40.47.10 218 393 4.4E-17 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS39080 dbf3b7961db7c61987c08315b6ea8c73 207 Gene3D G3DSA:1.10.10.60 1 68 9.3E-13 T 29-03-2018 SMALA_RS39080 dbf3b7961db7c61987c08315b6ea8c73 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 69 1.7E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS39080 dbf3b7961db7c61987c08315b6ea8c73 207 SUPERFAMILY SSF48498 92 202 1.54E-9 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS39080 dbf3b7961db7c61987c08315b6ea8c73 207 Gene3D G3DSA:1.10.357.10 69 206 2.7E-15 T 29-03-2018 SMALA_RS39080 dbf3b7961db7c61987c08315b6ea8c73 207 SUPERFAMILY SSF46689 10 92 1.44E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS01415 1d29fda786c25b200b52dd7b5137227a 340 SUPERFAMILY SSF51445 72 313 1.95E-22 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS01415 1d29fda786c25b200b52dd7b5137227a 340 Gene3D G3DSA:3.20.20.80 25 340 1.6E-36 T 29-03-2018 SMALA_RS15910 8a129d075a92fcee287d2d900cbbc79f 250 TIGRFAM TIGR03089 TIGR03089: TIGR03089 family protein 11 246 4.7E-82 T 29-03-2018 IPR017523 Conserved hypothetical protein CHP03089 SMALA_RS15910 8a129d075a92fcee287d2d900cbbc79f 250 Gene3D G3DSA:3.40.50.980 147 249 5.1E-7 T 29-03-2018 SMALA_RS15910 8a129d075a92fcee287d2d900cbbc79f 250 SUPERFAMILY SSF56801 3 247 3.01E-21 T 29-03-2018 SMALA_RS15910 8a129d075a92fcee287d2d900cbbc79f 250 Gene3D G3DSA:3.40.50.980 3 91 2.5E-11 T 29-03-2018 SMALA_RS15570 60ee315989d2862397c68d4e02371ced 457 Gene3D G3DSA:1.10.3720.10 39 457 3.1E-71 T 29-03-2018 SMALA_RS15570 60ee315989d2862397c68d4e02371ced 457 SUPERFAMILY SSF161098 309 445 3.34E-47 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS15570 60ee315989d2862397c68d4e02371ced 457 SUPERFAMILY SSF161098 78 168 3.34E-47 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS15570 60ee315989d2862397c68d4e02371ced 457 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 313 445 7.3E-21 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS15570 60ee315989d2862397c68d4e02371ced 457 SUPERFAMILY SSF160964 38 86 3.14E-6 T 29-03-2018 SMALA_RS39100 2466132298388983d712f7beeee29ea8 973 Pfam PF13191 AAA ATPase domain 35 192 9.6E-16 T 29-03-2018 SMALA_RS39100 2466132298388983d712f7beeee29ea8 973 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 917 933 3.8E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS39100 2466132298388983d712f7beeee29ea8 973 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 903 917 3.8E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS39100 2466132298388983d712f7beeee29ea8 973 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 933 945 3.8E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS39100 2466132298388983d712f7beeee29ea8 973 ProSitePatterns PS00622 LuxR-type HTH domain signature. 917 944 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS39100 2466132298388983d712f7beeee29ea8 973 Gene3D G3DSA:1.10.10.10 913 959 5.4E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS39100 2466132298388983d712f7beeee29ea8 973 SUPERFAMILY SSF48452 599 675 8.67E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS39100 2466132298388983d712f7beeee29ea8 973 SUPERFAMILY SSF48452 720 790 8.67E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS39100 2466132298388983d712f7beeee29ea8 973 Gene3D G3DSA:1.25.40.10 408 683 2.1E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS39100 2466132298388983d712f7beeee29ea8 973 Gene3D G3DSA:1.10.10.10 284 361 0.098 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS39100 2466132298388983d712f7beeee29ea8 973 Gene3D G3DSA:1.25.40.10 712 912 5.4E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS39100 2466132298388983d712f7beeee29ea8 973 SUPERFAMILY SSF52540 131 199 1.11E-6 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS39100 2466132298388983d712f7beeee29ea8 973 SUPERFAMILY SSF52540 35 100 1.11E-6 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS39100 2466132298388983d712f7beeee29ea8 973 Gene3D G3DSA:3.40.50.300 25 199 3.1E-5 T 29-03-2018 SMALA_RS39100 2466132298388983d712f7beeee29ea8 973 SMART SM00421 900 958 1.2E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS39100 2466132298388983d712f7beeee29ea8 973 Pfam PF00196 Bacterial regulatory proteins, luxR family 903 949 8.3E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS39100 2466132298388983d712f7beeee29ea8 973 SUPERFAMILY SSF46894 893 949 3.74E-13 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 3519 3535 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 SUPERFAMILY SSF55048 2258 2319 1.12E-11 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 SMART SM00823 Phosphopantetheine attachment site 3263 3335 8.3E-32 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 SMART SM00823 Phosphopantetheine attachment site 1507 1579 2.7E-32 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 SMART SM00823 Phosphopantetheine attachment site 5097 5169 4.2E-34 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 SMART SM01294 3264 3331 1.0E-5 T 29-03-2018 SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 SMART SM01294 1508 1575 8.0E-7 T 29-03-2018 SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 SMART SM01294 5098 5165 8.8E-7 T 29-03-2018 SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 SUPERFAMILY SSF52151 2312 2414 3.92E-76 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 SUPERFAMILY SSF52151 2132 2253 3.92E-76 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 Pfam PF08990 Erythronolide synthase docking 2 27 2.1E-10 T 29-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 SUPERFAMILY SSF52151 4076 4173 1.23E-77 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 SUPERFAMILY SSF52151 3887 4015 1.23E-77 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 SUPERFAMILY SSF53901 1597 1971 7.18E-105 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 SUPERFAMILY SSF47336 3258 3371 7.59E-23 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 SUPERFAMILY SSF51735 4803 5004 2.52E-41 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1218 1397 9.4E-55 T 29-03-2018 SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4804 4984 6.8E-60 T 29-03-2018 SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2981 3161 2.1E-58 T 29-03-2018 SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1762 1778 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 SUPERFAMILY SSF51735 2980 3188 2.13E-48 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1534 1549 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 SMART SM00825 Beta-ketoacyl synthase 36 465 1.7E-215 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 SMART SM00825 Beta-ketoacyl synthase 3358 3784 2.6E-236 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 SMART SM00825 Beta-ketoacyl synthase 1601 2027 6.9E-222 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 Pfam PF08659 KR domain 4804 4982 9.3E-59 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 Pfam PF08659 KR domain 2981 3159 3.6E-57 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 Pfam PF08659 KR domain 1218 1396 1.5E-56 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 SUPERFAMILY SSF51735 1215 1433 2.3E-45 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 SUPERFAMILY SSF55048 4013 4075 1.57E-11 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 Gene3D G3DSA:3.40.366.10 749 872 3.0E-27 T 29-03-2018 SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 Gene3D G3DSA:3.40.366.10 4068 4188 7.8E-28 T 29-03-2018 SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 Gene3D G3DSA:3.40.366.10 2311 2437 2.6E-27 T 29-03-2018 SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 Pfam PF00550 Phosphopantetheine attachment site 1509 1575 8.9E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 Pfam PF00550 Phosphopantetheine attachment site 3265 3331 6.6E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 Pfam PF00550 Phosphopantetheine attachment site 5099 5165 8.7E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 3614 3731 1.2E-43 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 292 409 1.1E-42 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1857 1974 1.2E-44 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 SUPERFAMILY SSF51735 4674 4788 2.17E-31 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 SUPERFAMILY SSF51735 4568 4639 2.17E-31 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 SUPERFAMILY SSF52151 758 859 1.67E-76 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 SUPERFAMILY SSF52151 569 697 1.67E-76 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 SUPERFAMILY SSF55048 696 757 4.32E-12 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 SUPERFAMILY SSF47336 1504 1614 3.66E-23 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 ProSitePatterns PS00012 Phosphopantetheine attachment site. 5124 5139 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 Pfam PF14765 Polyketide synthase dehydratase 4262 4562 1.4E-54 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 Pfam PF14765 Polyketide synthase dehydratase 2496 2773 9.8E-53 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 Pfam PF00698 Acyl transferase domain 572 886 1.6E-56 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 Pfam PF00698 Acyl transferase domain 2134 2447 1.3E-56 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 Pfam PF00698 Acyl transferase domain 3890 4215 1.6E-54 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 SUPERFAMILY SSF51735 984 1205 1.0E-51 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 SUPERFAMILY SSF53901 3351 3728 3.49E-106 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 Gene3D G3DSA:1.10.1200.10 5085 5177 3.0E-21 T 29-03-2018 SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 Gene3D G3DSA:1.10.1200.10 1487 1584 1.8E-18 T 29-03-2018 SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 Gene3D G3DSA:3.40.50.720 4801 5084 1.9E-43 T 29-03-2018 SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3290 3305 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 Gene3D G3DSA:3.40.366.10 569 706 1.1E-45 T 29-03-2018 SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 Gene3D G3DSA:3.40.366.10 3887 4024 2.0E-47 T 29-03-2018 SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 Gene3D G3DSA:3.40.366.10 2131 2268 1.3E-47 T 29-03-2018 SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 Gene3D G3DSA:3.30.70.250 2269 2310 1.3E-18 T 29-03-2018 SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 Gene3D G3DSA:3.30.70.250 707 748 5.7E-19 T 29-03-2018 SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 Gene3D G3DSA:3.30.70.250 4025 4067 9.4E-18 T 29-03-2018 SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1599 1849 1.1E-91 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 284 1.8E-89 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3356 3606 3.0E-96 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 SUPERFAMILY SSF47336 5090 5175 2.09E-22 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 197 213 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2135 2428 1.5E-127 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 573 868 5.0E-131 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 3891 4195 2.8E-130 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 SMART SM00826 4262 4450 1.3E-82 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 SMART SM00826 2496 2660 7.5E-82 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 Gene3D G3DSA:3.40.50.720 1211 1470 6.6E-51 T 29-03-2018 SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 Gene3D G3DSA:3.40.50.720 2973 3220 4.1E-54 T 29-03-2018 SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 SUPERFAMILY SSF53901 30 408 1.06E-99 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 Gene3D G3DSA:3.40.47.10 3621 3782 2.0E-63 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 Gene3D G3DSA:3.40.47.10 1864 2025 3.7E-63 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 Gene3D G3DSA:3.40.47.10 299 463 3.7E-58 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 Gene3D G3DSA:3.40.47.10 3356 3618 7.1E-91 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 Gene3D G3DSA:3.40.47.10 1593 1861 2.8E-84 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 Gene3D G3DSA:3.40.47.10 26 296 9.2E-85 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 SUPERFAMILY SSF51735 2779 2966 7.87E-35 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 Gene3D G3DSA:1.10.1200.10 3257 3355 5.1E-19 T 29-03-2018 SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1977 2092 1.1E-14 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 3734 3849 1.0E-14 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13780 6a7f53e3126527d22121490107c553f9 5250 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 412 536 3.4E-14 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS14620 ea2beb311192cc5fcb79409e6cd60bf5 256 Gene3D G3DSA:3.40.50.300 3 255 6.5E-75 T 29-03-2018 SMALA_RS14620 ea2beb311192cc5fcb79409e6cd60bf5 256 TIGRFAM TIGR03005 ectoine_ehuA: ectoine/hydroxyectoine ABC transporter, ATP-binding protein EhuA 7 256 1.0E-116 T 29-03-2018 IPR014343 Ectoine/hydroxyectoine ABC transporter, ATP-binding protein SMALA_RS14620 ea2beb311192cc5fcb79409e6cd60bf5 256 Pfam PF00005 ABC transporter 22 180 9.1E-37 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS14620 ea2beb311192cc5fcb79409e6cd60bf5 256 PIRSF PIRSF039085 3 256 1.8E-99 T 29-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 SMALA_RS14620 ea2beb311192cc5fcb79409e6cd60bf5 256 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS14620 ea2beb311192cc5fcb79409e6cd60bf5 256 SMART SM00382 31 229 8.0E-21 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS14620 ea2beb311192cc5fcb79409e6cd60bf5 256 SUPERFAMILY SSF52540 6 251 1.73E-76 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS03465 850009b2a0b439a95483ec84d820c871 254 PRINTS PR00783 Major intrinsic protein family signature 47 71 1.1E-42 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMALA_RS03465 850009b2a0b439a95483ec84d820c871 254 PRINTS PR00783 Major intrinsic protein family signature 141 159 1.1E-42 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMALA_RS03465 850009b2a0b439a95483ec84d820c871 254 PRINTS PR00783 Major intrinsic protein family signature 5 24 1.1E-42 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMALA_RS03465 850009b2a0b439a95483ec84d820c871 254 PRINTS PR00783 Major intrinsic protein family signature 233 253 1.1E-42 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMALA_RS03465 850009b2a0b439a95483ec84d820c871 254 PRINTS PR00783 Major intrinsic protein family signature 186 208 1.1E-42 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMALA_RS03465 850009b2a0b439a95483ec84d820c871 254 PRINTS PR00783 Major intrinsic protein family signature 83 102 1.1E-42 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMALA_RS03465 850009b2a0b439a95483ec84d820c871 254 Pfam PF00230 Major intrinsic protein 8 250 4.5E-40 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMALA_RS03465 850009b2a0b439a95483ec84d820c871 254 ProSitePatterns PS00221 MIP family signature. 65 73 - T 29-03-2018 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMALA_RS03465 850009b2a0b439a95483ec84d820c871 254 Gene3D G3DSA:1.20.1080.10 2 254 1.4E-73 T 29-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 SMALA_RS03465 850009b2a0b439a95483ec84d820c871 254 SUPERFAMILY SSF81338 7 252 6.8E-60 T 29-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 SMALA_RS17675 d4ffb07c255e41f2476c97459b04455a 264 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 21 255 4.2E-70 T 29-03-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 SMALA_RS17675 d4ffb07c255e41f2476c97459b04455a 264 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 18 255 40.686 T 29-03-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 SMALA_RS17675 d4ffb07c255e41f2476c97459b04455a 264 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 20 256 1.6E-66 T 29-03-2018 IPR034683 Cytidylyltransferase IspD/TarI GO:0070567 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 SMALA_RS17675 d4ffb07c255e41f2476c97459b04455a 264 SUPERFAMILY SSF53448 19 255 4.96E-52 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS17675 d4ffb07c255e41f2476c97459b04455a 264 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 123 130 - T 29-03-2018 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 SMALA_RS17675 d4ffb07c255e41f2476c97459b04455a 264 Gene3D G3DSA:3.90.550.10 10 262 7.6E-47 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS27690 e38bcfeba0a0b020018838f1ad5f06f0 1094 Pfam PF13191 AAA ATPase domain 63 233 5.4E-29 T 29-03-2018 SMALA_RS27690 e38bcfeba0a0b020018838f1ad5f06f0 1094 SMART SM00421 1021 1078 1.6E-26 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS27690 e38bcfeba0a0b020018838f1ad5f06f0 1094 Gene3D G3DSA:1.10.10.10 1031 1086 2.8E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS27690 e38bcfeba0a0b020018838f1ad5f06f0 1094 SUPERFAMILY SSF46894 1016 1084 2.69E-21 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS27690 e38bcfeba0a0b020018838f1ad5f06f0 1094 Gene3D G3DSA:1.25.40.10 611 1030 7.3E-18 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS27690 e38bcfeba0a0b020018838f1ad5f06f0 1094 SUPERFAMILY SSF48452 614 773 1.1E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS27690 e38bcfeba0a0b020018838f1ad5f06f0 1094 SUPERFAMILY SSF52540 63 150 5.43E-9 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS27690 e38bcfeba0a0b020018838f1ad5f06f0 1094 SUPERFAMILY SSF52540 194 310 5.43E-9 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS27690 e38bcfeba0a0b020018838f1ad5f06f0 1094 Pfam PF00196 Bacterial regulatory proteins, luxR family 1024 1078 2.6E-20 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS27690 e38bcfeba0a0b020018838f1ad5f06f0 1094 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 1024 1038 3.2E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS27690 e38bcfeba0a0b020018838f1ad5f06f0 1094 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 1038 1054 3.2E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS27690 e38bcfeba0a0b020018838f1ad5f06f0 1094 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 1054 1066 3.2E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS27690 e38bcfeba0a0b020018838f1ad5f06f0 1094 Gene3D G3DSA:3.40.50.300 63 479 2.9E-9 T 29-03-2018 SMALA_RS05405 89f1bfb41198b04877c226121681b4bd 258 SUPERFAMILY SSF46785 8 71 8.92E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS05405 89f1bfb41198b04877c226121681b4bd 258 Pfam PF00455 DeoR C terminal sensor domain 80 235 4.2E-43 T 29-03-2018 IPR014036 DeoR C-terminal sensor domain SMALA_RS05405 89f1bfb41198b04877c226121681b4bd 258 Gene3D G3DSA:3.40.50.1360 83 239 1.2E-31 T 29-03-2018 SMALA_RS05405 89f1bfb41198b04877c226121681b4bd 258 ProSitePatterns PS00894 DeoR-type HTH domain signature. 10 44 - T 29-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 SMALA_RS05405 89f1bfb41198b04877c226121681b4bd 258 Pfam PF08220 DeoR-like helix-turn-helix domain 10 63 9.0E-14 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMALA_RS05405 89f1bfb41198b04877c226121681b4bd 258 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 42 60 1.4E-5 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMALA_RS05405 89f1bfb41198b04877c226121681b4bd 258 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 28 42 1.4E-5 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMALA_RS05405 89f1bfb41198b04877c226121681b4bd 258 Gene3D G3DSA:1.10.10.10 6 82 9.0E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS05405 89f1bfb41198b04877c226121681b4bd 258 SMART SM01134 77 237 1.1E-52 T 29-03-2018 SMALA_RS05405 89f1bfb41198b04877c226121681b4bd 258 SUPERFAMILY SSF100950 79 236 7.64E-23 T 29-03-2018 SMALA_RS05405 89f1bfb41198b04877c226121681b4bd 258 SMART SM00420 10 62 1.5E-12 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMALA_RS40560 f5927b4c4b72d4f3590a96d2d6272b52 269 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 32 259 1.7E-59 T 29-03-2018 SMALA_RS40560 f5927b4c4b72d4f3590a96d2d6272b52 269 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 154 1.1E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40560 f5927b4c4b72d4f3590a96d2d6272b52 269 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 93 104 1.1E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40560 f5927b4c4b72d4f3590a96d2d6272b52 269 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 166 185 1.1E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40560 f5927b4c4b72d4f3590a96d2d6272b52 269 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 26 197 0.0059 T 29-03-2018 SMALA_RS40560 f5927b4c4b72d4f3590a96d2d6272b52 269 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 153 181 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMALA_RS40560 f5927b4c4b72d4f3590a96d2d6272b52 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 27 44 1.4E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40560 f5927b4c4b72d4f3590a96d2d6272b52 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 156 1.4E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40560 f5927b4c4b72d4f3590a96d2d6272b52 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 1.4E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40560 f5927b4c4b72d4f3590a96d2d6272b52 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 93 104 1.4E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40560 f5927b4c4b72d4f3590a96d2d6272b52 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 187 204 1.4E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40560 f5927b4c4b72d4f3590a96d2d6272b52 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 185 1.4E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40560 f5927b4c4b72d4f3590a96d2d6272b52 269 Gene3D G3DSA:3.40.50.720 1 261 2.7E-69 T 29-03-2018 SMALA_RS40560 f5927b4c4b72d4f3590a96d2d6272b52 269 SUPERFAMILY SSF51735 24 260 1.99E-74 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 Gene3D G3DSA:1.10.1200.10 7187 7307 5.0E-20 T 29-03-2018 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 Gene3D G3DSA:1.10.1200.10 1766 1852 1.8E-19 T 29-03-2018 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 ProSitePatterns PS00012 Phosphopantetheine attachment site. 7219 7234 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 Gene3D G3DSA:3.40.47.10 28 298 9.3E-85 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 Gene3D G3DSA:3.40.47.10 5483 5753 1.6E-89 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 Gene3D G3DSA:3.40.47.10 1853 2115 4.5E-86 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 Gene3D G3DSA:3.40.47.10 3655 3925 7.8E-89 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 Gene3D G3DSA:3.40.50.720 6900 7152 1.1E-50 T 29-03-2018 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 SUPERFAMILY SSF47336 1755 1867 1.57E-23 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 Pfam PF14765 Polyketide synthase dehydratase 6386 6668 9.6E-59 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 Pfam PF14765 Polyketide synthase dehydratase 2747 3020 1.9E-55 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 Pfam PF14765 Polyketide synthase dehydratase 935 1207 4.0E-55 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 Pfam PF14765 Polyketide synthase dehydratase 4559 4832 2.4E-53 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 Gene3D G3DSA:3.40.366.10 4370 4491 1.1E-26 T 29-03-2018 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 Gene3D G3DSA:3.40.366.10 2565 2691 4.9E-27 T 29-03-2018 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 5654 5670 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 Gene3D G3DSA:3.40.50.720 5111 5390 3.3E-46 T 29-03-2018 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 Gene3D G3DSA:3.40.50.720 1470 1765 3.4E-47 T 29-03-2018 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 Gene3D G3DSA:3.40.50.720 3284 3565 3.6E-47 T 29-03-2018 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 2016 2032 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 SUPERFAMILY SSF47336 3567 3678 1.03E-21 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 ProSitePatterns PS00012 Phosphopantetheine attachment site. 5427 5442 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 Gene3D G3DSA:3.40.47.10 3928 4089 6.9E-63 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 Gene3D G3DSA:3.40.47.10 5756 5917 1.3E-62 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 Gene3D G3DSA:3.40.47.10 301 462 4.7E-62 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 Gene3D G3DSA:3.40.47.10 2118 2279 4.5E-61 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 Gene3D G3DSA:1.10.1200.10 5391 5473 2.5E-16 T 29-03-2018 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 SUPERFAMILY SSF55048 6147 6208 8.63E-11 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 Gene3D G3DSA:3.10.129.10 4561 4683 1.4E-5 T 29-03-2018 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 Gene3D G3DSA:3.10.129.10 938 1061 1.5E-5 T 29-03-2018 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 Gene3D G3DSA:3.10.129.10 2749 2871 6.9E-6 T 29-03-2018 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 Gene3D G3DSA:3.10.129.10 6388 6513 5.0E-7 T 29-03-2018 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 Gene3D G3DSA:3.30.70.250 714 750 1.1E-18 T 29-03-2018 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 Gene3D G3DSA:3.30.70.250 2524 2564 1.9E-17 T 29-03-2018 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 Gene3D G3DSA:3.30.70.250 4329 4369 3.4E-19 T 29-03-2018 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 Gene3D G3DSA:3.30.70.250 6158 6203 9.1E-18 T 29-03-2018 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 3826 3842 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 SUPERFAMILY SSF53901 1849 2225 1.24E-104 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3288 3468 1.7E-61 T 29-03-2018 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1474 1654 2.4E-61 T 29-03-2018 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5115 5295 6.5E-63 T 29-03-2018 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6906 7086 2.5E-65 T 29-03-2018 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 Gene3D G3DSA:3.40.366.10 4191 4328 3.7E-48 T 29-03-2018 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 Gene3D G3DSA:3.40.366.10 2386 2523 8.0E-48 T 29-03-2018 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 Gene3D G3DSA:3.40.366.10 6020 6157 5.5E-44 T 29-03-2018 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 SUPERFAMILY SSF47336 5396 5506 1.83E-21 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 SUPERFAMILY SSF51735 1473 1670 3.31E-46 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 Pfam PF00550 Phosphopantetheine attachment site 7195 7260 6.0E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 Pfam PF00550 Phosphopantetheine attachment site 3574 3640 4.9E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 Pfam PF00550 Phosphopantetheine attachment site 5402 5468 2.5E-9 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 Pfam PF00550 Phosphopantetheine attachment site 1762 1828 1.7E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 SUPERFAMILY SSF51735 3128 3272 2.01E-28 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 SUPERFAMILY SSF51735 3030 3083 2.01E-28 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 Pfam PF00698 Acyl transferase domain 575 887 3.7E-58 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 Pfam PF00698 Acyl transferase domain 4194 4493 6.6E-56 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 Pfam PF00698 Acyl transferase domain 6023 6336 7.0E-51 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 Pfam PF00698 Acyl transferase domain 2389 2699 1.9E-55 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1787 1802 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 199 215 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 SMART SM00826 4559 4722 2.1E-85 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 SMART SM00826 2747 2910 5.3E-85 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 SMART SM00826 6386 6555 8.6E-84 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 SMART SM00826 935 1098 2.2E-85 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 Gene3D G3DSA:1.10.1200.10 3566 3649 1.0E-16 T 29-03-2018 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 SMART SM00823 Phosphopantetheine attachment site 7192 7264 3.4E-34 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 SMART SM00823 Phosphopantetheine attachment site 5400 5472 3.1E-29 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 SMART SM00823 Phosphopantetheine attachment site 1760 1832 2.5E-33 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 SMART SM00823 Phosphopantetheine attachment site 3572 3644 1.9E-29 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 SUPERFAMILY SSF52151 2387 2508 4.97E-76 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 SUPERFAMILY SSF52151 2567 2678 4.97E-76 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 Pfam PF08659 KR domain 5115 5294 1.1E-58 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 Pfam PF08659 KR domain 1474 1652 1.7E-59 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 Pfam PF08659 KR domain 3288 3467 1.4E-58 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 Pfam PF08659 KR domain 6906 7085 5.1E-61 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 576 868 7.9E-128 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 6024 6318 5.1E-119 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 4195 4488 2.4E-128 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2390 2680 4.7E-126 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2111 2228 2.2E-43 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 5749 5866 4.7E-44 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 3921 4038 4.7E-44 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 294 411 5.9E-44 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 SMART SM00825 Beta-ketoacyl synthase 1854 2281 2.0E-228 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 SMART SM00825 Beta-ketoacyl synthase 38 464 6.5E-222 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 SMART SM00825 Beta-ketoacyl synthase 5493 5919 1.9E-230 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 SMART SM00825 Beta-ketoacyl synthase 3665 4091 1.9E-231 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 SUPERFAMILY SSF52151 573 694 2.88E-76 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 SUPERFAMILY SSF52151 753 868 2.88E-76 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 SUPERFAMILY SSF51735 1217 1270 1.18E-29 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 SUPERFAMILY SSF51735 1315 1459 1.18E-29 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 Gene3D G3DSA:3.40.366.10 6204 6325 6.9E-25 T 29-03-2018 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 SUPERFAMILY SSF55048 2513 2574 1.31E-10 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 SUPERFAMILY SSF52151 6021 6142 1.73E-73 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 SUPERFAMILY SSF52151 6201 6306 1.73E-73 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 Gene3D G3DSA:3.40.366.10 751 872 6.5E-30 T 29-03-2018 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 Pfam PF08990 Erythronolide synthase docking 4 29 3.7E-10 T 29-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 SUPERFAMILY SSF47336 7185 7270 1.96E-22 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 SUPERFAMILY SSF53901 33 408 6.95E-101 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 SUPERFAMILY SSF51735 6677 6891 6.69E-32 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 4041 4159 3.5E-14 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2231 2351 2.3E-14 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 5869 5988 6.6E-15 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 414 540 6.2E-14 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 SUPERFAMILY SSF51735 5114 5325 2.27E-44 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 SUPERFAMILY SSF55048 699 760 1.01E-11 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 SUPERFAMILY SSF52151 4372 4482 1.31E-77 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 SUPERFAMILY SSF52151 4192 4313 1.31E-77 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 Gene3D G3DSA:3.40.366.10 569 713 8.5E-53 T 29-03-2018 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 SUPERFAMILY SSF51735 6906 7099 2.88E-46 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3599 3614 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 SUPERFAMILY SSF55048 4318 4379 4.45E-12 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1852 2103 1.7E-94 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3663 3913 8.9E-93 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 5491 5741 1.0E-93 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 36 286 1.0E-87 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 SUPERFAMILY SSF53901 3659 4035 5.65E-104 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 SUPERFAMILY SSF53901 5487 5863 9.09E-106 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 SMART SM01294 3573 3640 3.9E-6 T 29-03-2018 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 SMART SM01294 5401 5468 1.3E-5 T 29-03-2018 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 SMART SM01294 1761 1828 2.1E-6 T 29-03-2018 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 SMART SM01294 7193 7260 6.3E-6 T 29-03-2018 SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 SUPERFAMILY SSF51735 3286 3522 7.41E-46 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS13775 d938dd84ecddc5163e02db7e4c867a97 7345 SUPERFAMILY SSF51735 4929 5102 9.58E-31 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS27845 96dcc5c58f24a0a16e2e193379392464 194 Gene3D G3DSA:3.40.50.300 10 193 7.1E-18 T 29-03-2018 SMALA_RS27845 96dcc5c58f24a0a16e2e193379392464 194 SUPERFAMILY SSF52540 18 191 1.84E-21 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS27845 96dcc5c58f24a0a16e2e193379392464 194 Pfam PF03029 Conserved hypothetical ATP binding protein 22 189 2.0E-27 T 29-03-2018 IPR004130 GPN-loop GTPase SMALA_RS35940 ce94f095b7a5570b12d479a8df58eddd 958 Gene3D G3DSA:1.25.40.10 337 861 9.9E-16 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS35940 ce94f095b7a5570b12d479a8df58eddd 958 SUPERFAMILY SSF46894 890 948 1.73E-15 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS35940 ce94f095b7a5570b12d479a8df58eddd 958 SMART SM00421 893 950 3.8E-19 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS35940 ce94f095b7a5570b12d479a8df58eddd 958 Pfam PF00196 Bacterial regulatory proteins, luxR family 896 946 1.5E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS35940 ce94f095b7a5570b12d479a8df58eddd 958 SUPERFAMILY SSF48452 584 689 8.67E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS35940 ce94f095b7a5570b12d479a8df58eddd 958 ProSitePatterns PS00622 LuxR-type HTH domain signature. 910 937 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS35940 ce94f095b7a5570b12d479a8df58eddd 958 Gene3D G3DSA:3.40.50.300 8 211 2.1E-9 T 29-03-2018 SMALA_RS35940 ce94f095b7a5570b12d479a8df58eddd 958 Gene3D G3DSA:1.10.10.10 862 954 3.3E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS35940 ce94f095b7a5570b12d479a8df58eddd 958 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 926 938 2.9E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS35940 ce94f095b7a5570b12d479a8df58eddd 958 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 910 926 2.9E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS35940 ce94f095b7a5570b12d479a8df58eddd 958 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 896 910 2.9E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS35940 ce94f095b7a5570b12d479a8df58eddd 958 Pfam PF13191 AAA ATPase domain 12 175 2.9E-17 T 29-03-2018 SMALA_RS35940 ce94f095b7a5570b12d479a8df58eddd 958 SUPERFAMILY SSF52540 13 81 1.71E-11 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS35940 ce94f095b7a5570b12d479a8df58eddd 958 SUPERFAMILY SSF52540 123 253 1.71E-11 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS25545 2cc40793050b49da4e82054272d01689 651 Gene3D G3DSA:3.50.50.60 2 346 9.1E-53 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS25545 2cc40793050b49da4e82054272d01689 651 Gene3D G3DSA:3.50.50.60 347 446 7.1E-19 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS25545 2cc40793050b49da4e82054272d01689 651 SUPERFAMILY SSF46977 493 648 3.66E-38 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMALA_RS25545 2cc40793050b49da4e82054272d01689 651 SUPERFAMILY SSF56425 243 389 1.94E-33 T 29-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMALA_RS25545 2cc40793050b49da4e82054272d01689 651 Pfam PF00890 FAD binding domain 10 430 5.1E-94 T 29-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMALA_RS25545 2cc40793050b49da4e82054272d01689 651 PIRSF PIRSF000171 1 612 1.4E-37 T 29-03-2018 SMALA_RS25545 2cc40793050b49da4e82054272d01689 651 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 394 416 2.2E-8 T 29-03-2018 SMALA_RS25545 2cc40793050b49da4e82054272d01689 651 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 2.2E-8 T 29-03-2018 SMALA_RS25545 2cc40793050b49da4e82054272d01689 651 SUPERFAMILY SSF51905 4 131 3.17E-71 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS25545 2cc40793050b49da4e82054272d01689 651 SUPERFAMILY SSF51905 393 453 3.17E-71 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS25545 2cc40793050b49da4e82054272d01689 651 SUPERFAMILY SSF51905 157 270 3.17E-71 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS25545 2cc40793050b49da4e82054272d01689 651 Gene3D G3DSA:1.20.58.100 469 586 5.8E-29 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMALA_RS25545 2cc40793050b49da4e82054272d01689 651 Pfam PF02910 Fumarate reductase flavoprotein C-term 500 597 6.8E-23 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMALA_RS22745 4f19305d9c90e911bc489d54694186e5 175 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 45 175 33.15 T 29-03-2018 IPR023035 Ribosomal protein S9, bacterial/plastid SMALA_RS22745 4f19305d9c90e911bc489d54694186e5 175 ProSitePatterns PS00360 Ribosomal protein S9 signature. 113 131 - T 29-03-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 SMALA_RS22745 4f19305d9c90e911bc489d54694186e5 175 Gene3D G3DSA:3.30.230.10 44 175 8.1E-48 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SMALA_RS22745 4f19305d9c90e911bc489d54694186e5 175 Pfam PF00380 Ribosomal protein S9/S16 54 175 3.5E-43 T 29-03-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 SMALA_RS22745 4f19305d9c90e911bc489d54694186e5 175 SUPERFAMILY SSF54211 51 175 3.79E-43 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SMALA_RS22140 d94cc9c2ad82daf49eea6330a53340b7 451 ProSitePatterns PS00667 Respiratory-chain NADH dehydrogenase subunit 1 signature 1. 62 77 - T 29-03-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS22140 d94cc9c2ad82daf49eea6330a53340b7 451 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 229 242 - T 29-03-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS22140 d94cc9c2ad82daf49eea6330a53340b7 451 Pfam PF00146 NADH dehydrogenase 23 346 2.8E-122 T 29-03-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS22140 d94cc9c2ad82daf49eea6330a53340b7 451 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 16 353 23.977 T 29-03-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS08080 8bdea8bcf496bfeb2e1ae9e2e15afb33 272 PIRSF PIRSF006648 1 271 5.3E-67 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMALA_RS08080 8bdea8bcf496bfeb2e1ae9e2e15afb33 272 Pfam PF01061 ABC-2 type transporter 22 236 9.4E-28 T 29-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 SMALA_RS08080 8bdea8bcf496bfeb2e1ae9e2e15afb33 272 PRINTS PR00164 ABC-2 type transport system membrane protein signature 38 59 6.9E-5 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMALA_RS08080 8bdea8bcf496bfeb2e1ae9e2e15afb33 272 PRINTS PR00164 ABC-2 type transport system membrane protein signature 194 213 6.9E-5 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMALA_RS08080 8bdea8bcf496bfeb2e1ae9e2e15afb33 272 PRINTS PR00164 ABC-2 type transport system membrane protein signature 117 142 6.9E-5 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMALA_RS08080 8bdea8bcf496bfeb2e1ae9e2e15afb33 272 PRINTS PR00164 ABC-2 type transport system membrane protein signature 214 233 6.9E-5 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMALA_RS37510 e2c527c468973c28c8d63ada627b73cf 321 TIGRFAM TIGR03438 egtD_ergothio: dimethylhistidine N-methyltransferase 19 317 2.7E-112 T 29-03-2018 IPR035094 Histidine N-alpha-methyltransferase KEGG: 00340+2.1.1.44|MetaCyc: PWY-7255|MetaCyc: PWY-7550 SMALA_RS37510 e2c527c468973c28c8d63ada627b73cf 321 SUPERFAMILY SSF53335 27 193 2.57E-14 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS37510 e2c527c468973c28c8d63ada627b73cf 321 SUPERFAMILY SSF53335 283 316 2.57E-14 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS37510 e2c527c468973c28c8d63ada627b73cf 321 PIRSF PIRSF018005 4 321 7.7E-134 T 29-03-2018 IPR017804 Methyltransferase EgtD-like SMALA_RS37510 e2c527c468973c28c8d63ada627b73cf 321 Hamap MF_02037 Histidine N-alpha-methyltransferase [egtD]. 6 320 53.576 T 29-03-2018 IPR032888 Histidine N-alpha-methyltransferase, Actinobacteria-type GO:0008276|GO:0052699 KEGG: 00340+2.1.1.44|MetaCyc: PWY-7255|MetaCyc: PWY-7550 SMALA_RS37510 e2c527c468973c28c8d63ada627b73cf 321 Pfam PF10017 Histidine-specific methyltransferase, SAM-dependent 19 319 1.3E-112 T 29-03-2018 IPR019257 Histidine-specific methyltransferase, SAM-dependent SMALA_RS37510 e2c527c468973c28c8d63ada627b73cf 321 Gene3D G3DSA:3.40.50.150 13 320 1.3E-24 T 29-03-2018 SMALA_RS29475 3f7cac476511622a8eaa2a1e51806cbe 2369 Pfam PF13193 AMP-binding enzyme C-terminal domain 872 947 2.3E-15 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS29475 3f7cac476511622a8eaa2a1e51806cbe 2369 Pfam PF13193 AMP-binding enzyme C-terminal domain 1936 2011 8.4E-16 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS29475 3f7cac476511622a8eaa2a1e51806cbe 2369 Gene3D G3DSA:3.30.559.10 1 208 3.7E-41 T 29-03-2018 SMALA_RS29475 3f7cac476511622a8eaa2a1e51806cbe 2369 Gene3D G3DSA:3.30.559.10 1042 1257 2.3E-47 T 29-03-2018 SMALA_RS29475 3f7cac476511622a8eaa2a1e51806cbe 2369 Gene3D G3DSA:3.40.50.980 457 619 1.7E-47 T 29-03-2018 SMALA_RS29475 3f7cac476511622a8eaa2a1e51806cbe 2369 ProSitePatterns PS00012 Phosphopantetheine attachment site. 995 1010 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS29475 3f7cac476511622a8eaa2a1e51806cbe 2369 SUPERFAMILY SSF52777 1057 1227 2.67E-50 T 29-03-2018 SMALA_RS29475 3f7cac476511622a8eaa2a1e51806cbe 2369 SUPERFAMILY SSF56801 424 984 7.72E-153 T 29-03-2018 SMALA_RS29475 3f7cac476511622a8eaa2a1e51806cbe 2369 Gene3D G3DSA:3.30.300.30 859 976 5.1E-42 T 29-03-2018 SMALA_RS29475 3f7cac476511622a8eaa2a1e51806cbe 2369 Gene3D G3DSA:3.30.300.30 1923 2039 2.2E-42 T 29-03-2018 SMALA_RS29475 3f7cac476511622a8eaa2a1e51806cbe 2369 SUPERFAMILY SSF53474 2107 2365 1.12E-50 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS29475 3f7cac476511622a8eaa2a1e51806cbe 2369 SMART SM00823 Phosphopantetheine attachment site 2036 2105 7.7E-6 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS29475 3f7cac476511622a8eaa2a1e51806cbe 2369 SMART SM00823 Phosphopantetheine attachment site 971 1040 2.3E-7 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS29475 3f7cac476511622a8eaa2a1e51806cbe 2369 Gene3D G3DSA:3.40.50.980 1513 1665 1.2E-36 T 29-03-2018 SMALA_RS29475 3f7cac476511622a8eaa2a1e51806cbe 2369 Gene3D G3DSA:3.40.50.1820 2109 2366 2.2E-24 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS29475 3f7cac476511622a8eaa2a1e51806cbe 2369 Pfam PF00501 AMP-binding enzyme 1522 1928 1.2E-105 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS29475 3f7cac476511622a8eaa2a1e51806cbe 2369 Pfam PF00501 AMP-binding enzyme 465 864 2.2E-91 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS29475 3f7cac476511622a8eaa2a1e51806cbe 2369 Pfam PF00975 Thioesterase domain 2124 2350 1.1E-22 T 29-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 SMALA_RS29475 3f7cac476511622a8eaa2a1e51806cbe 2369 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 486 887 6.8E-130 T 29-03-2018 IPR010071 Amino acid adenylation domain SMALA_RS29475 3f7cac476511622a8eaa2a1e51806cbe 2369 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1544 1952 7.3E-140 T 29-03-2018 IPR010071 Amino acid adenylation domain SMALA_RS29475 3f7cac476511622a8eaa2a1e51806cbe 2369 Gene3D G3DSA:1.10.1200.10 977 1041 1.7E-24 T 29-03-2018 SMALA_RS29475 3f7cac476511622a8eaa2a1e51806cbe 2369 Gene3D G3DSA:3.40.50.980 620 772 2.1E-27 T 29-03-2018 SMALA_RS29475 3f7cac476511622a8eaa2a1e51806cbe 2369 Gene3D G3DSA:2.30.38.10 1833 1920 3.5E-24 T 29-03-2018 SMALA_RS29475 3f7cac476511622a8eaa2a1e51806cbe 2369 ProSitePatterns PS00455 Putative AMP-binding domain signature. 614 625 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS29475 3f7cac476511622a8eaa2a1e51806cbe 2369 SUPERFAMILY SSF47336 964 1037 2.36E-20 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS29475 3f7cac476511622a8eaa2a1e51806cbe 2369 SUPERFAMILY SSF52777 1239 1510 8.23E-63 T 29-03-2018 SMALA_RS29475 3f7cac476511622a8eaa2a1e51806cbe 2369 SUPERFAMILY SSF56801 1481 2049 2.75E-174 T 29-03-2018 SMALA_RS29475 3f7cac476511622a8eaa2a1e51806cbe 2369 SUPERFAMILY SSF52777 4 184 1.45E-43 T 29-03-2018 SMALA_RS29475 3f7cac476511622a8eaa2a1e51806cbe 2369 Pfam PF00668 Condensation domain 1054 1503 1.0E-97 T 29-03-2018 IPR001242 Condensation domain SMALA_RS29475 3f7cac476511622a8eaa2a1e51806cbe 2369 Pfam PF00668 Condensation domain 7 441 9.0E-88 T 29-03-2018 IPR001242 Condensation domain SMALA_RS29475 3f7cac476511622a8eaa2a1e51806cbe 2369 Gene3D G3DSA:1.10.1200.10 2040 2108 3.5E-23 T 29-03-2018 SMALA_RS29475 3f7cac476511622a8eaa2a1e51806cbe 2369 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2060 2075 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS29475 3f7cac476511622a8eaa2a1e51806cbe 2369 Pfam PF00550 Phosphopantetheine attachment site 2039 2101 4.4E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS29475 3f7cac476511622a8eaa2a1e51806cbe 2369 Pfam PF00550 Phosphopantetheine attachment site 974 1036 7.2E-15 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS29475 3f7cac476511622a8eaa2a1e51806cbe 2369 SUPERFAMILY SSF52777 190 453 8.78E-57 T 29-03-2018 SMALA_RS29475 3f7cac476511622a8eaa2a1e51806cbe 2369 Gene3D G3DSA:2.30.38.10 776 857 9.2E-24 T 29-03-2018 SMALA_RS29475 3f7cac476511622a8eaa2a1e51806cbe 2369 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1672 1683 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS29475 3f7cac476511622a8eaa2a1e51806cbe 2369 SUPERFAMILY SSF47336 2029 2102 3.01E-20 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS29475 3f7cac476511622a8eaa2a1e51806cbe 2369 Gene3D G3DSA:3.40.50.980 1666 1832 2.0E-58 T 29-03-2018 SMALA_RS30350 4ae0ce535edd8b1e702260ca58ef73d8 245 Gene3D G3DSA:3.40.50.720 2 190 1.4E-23 T 29-03-2018 SMALA_RS30350 4ae0ce535edd8b1e702260ca58ef73d8 245 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 6 94 3.1E-15 T 29-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal SMALA_RS30350 4ae0ce535edd8b1e702260ca58ef73d8 245 SUPERFAMILY SSF51735 6 198 5.91E-34 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS42190 47f9ef4504457e4ef3f2bcbafc6592cb 274 Gene3D G3DSA:3.40.50.1820 7 273 4.5E-51 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS42190 47f9ef4504457e4ef3f2bcbafc6592cb 274 PRINTS PR00111 Alpha/beta hydrolase fold signature 211 225 5.9E-10 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS42190 47f9ef4504457e4ef3f2bcbafc6592cb 274 PRINTS PR00111 Alpha/beta hydrolase fold signature 47 62 5.9E-10 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS42190 47f9ef4504457e4ef3f2bcbafc6592cb 274 PRINTS PR00111 Alpha/beta hydrolase fold signature 105 118 5.9E-10 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS42190 47f9ef4504457e4ef3f2bcbafc6592cb 274 PRINTS PR00111 Alpha/beta hydrolase fold signature 91 104 5.9E-10 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS42190 47f9ef4504457e4ef3f2bcbafc6592cb 274 Pfam PF00561 alpha/beta hydrolase fold 22 124 6.8E-22 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS42190 47f9ef4504457e4ef3f2bcbafc6592cb 274 SUPERFAMILY SSF53474 1 266 1.06E-63 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS28155 9b87b35270a14b2ee929fa664cb6fb8e 116 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 2 114 29.334 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS28155 9b87b35270a14b2ee929fa664cb6fb8e 116 PRINTS PR00061 Ribosomal protein L19 signature 4 33 1.1E-42 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS28155 9b87b35270a14b2ee929fa664cb6fb8e 116 PRINTS PR00061 Ribosomal protein L19 signature 34 63 1.1E-42 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS28155 9b87b35270a14b2ee929fa664cb6fb8e 116 PRINTS PR00061 Ribosomal protein L19 signature 88 113 1.1E-42 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS28155 9b87b35270a14b2ee929fa664cb6fb8e 116 SUPERFAMILY SSF50104 3 115 6.12E-46 T 29-03-2018 IPR008991 Translation protein SH3-like domain SMALA_RS28155 9b87b35270a14b2ee929fa664cb6fb8e 116 Pfam PF01245 Ribosomal protein L19 4 113 8.7E-50 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS28155 9b87b35270a14b2ee929fa664cb6fb8e 116 ProSitePatterns PS01015 Ribosomal protein L19 signature. 86 101 - T 29-03-2018 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS28155 9b87b35270a14b2ee929fa664cb6fb8e 116 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 3 113 1.1E-48 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS28155 9b87b35270a14b2ee929fa664cb6fb8e 116 PIRSF PIRSF002191 1 116 1.7E-49 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS09385 264860ee4f24bb230b0f5613aede1b9f 142 SUPERFAMILY SSF46785 7 136 2.86E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS09385 264860ee4f24bb230b0f5613aede1b9f 142 SMART SM00347 25 126 4.7E-13 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS09385 264860ee4f24bb230b0f5613aede1b9f 142 Pfam PF01047 MarR family 32 88 2.3E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS09385 264860ee4f24bb230b0f5613aede1b9f 142 Gene3D G3DSA:1.10.287.100 110 141 5.3E-13 T 29-03-2018 SMALA_RS09385 264860ee4f24bb230b0f5613aede1b9f 142 Gene3D G3DSA:1.10.10.10 2 109 1.1E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS06445 20c294986a32bd538af65509e485668a 3424 SUPERFAMILY SSF51735 1317 1559 3.56E-40 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS06445 20c294986a32bd538af65509e485668a 3424 SUPERFAMILY SSF53901 1686 2059 3.16E-102 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS06445 20c294986a32bd538af65509e485668a 3424 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1623 1638 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS06445 20c294986a32bd538af65509e485668a 3424 SUPERFAMILY SSF55048 674 731 3.79E-9 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS06445 20c294986a32bd538af65509e485668a 3424 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1853 1869 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS06445 20c294986a32bd538af65509e485668a 3424 Pfam PF08990 Erythronolide synthase docking 2 27 6.7E-8 T 29-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 SMALA_RS06445 20c294986a32bd538af65509e485668a 3424 SMART SM00826 906 1062 2.2E-73 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS06445 20c294986a32bd538af65509e485668a 3424 SMART SM00826 2575 2733 2.4E-60 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS06445 20c294986a32bd538af65509e485668a 3424 SUPERFAMILY SSF53901 29 405 1.14E-101 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS06445 20c294986a32bd538af65509e485668a 3424 Gene3D G3DSA:3.40.50.720 1315 1557 1.0E-44 T 29-03-2018 SMALA_RS06445 20c294986a32bd538af65509e485668a 3424 Gene3D G3DSA:3.40.50.720 2992 3228 6.6E-46 T 29-03-2018 SMALA_RS06445 20c294986a32bd538af65509e485668a 3424 SUPERFAMILY SSF51735 2782 2982 1.85E-16 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS06445 20c294986a32bd538af65509e485668a 3424 Gene3D G3DSA:3.30.70.250 678 728 7.1E-12 T 29-03-2018 SMALA_RS06445 20c294986a32bd538af65509e485668a 3424 Pfam PF14765 Polyketide synthase dehydratase 2575 2843 4.4E-50 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS06445 20c294986a32bd538af65509e485668a 3424 Pfam PF14765 Polyketide synthase dehydratase 907 1171 2.4E-51 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS06445 20c294986a32bd538af65509e485668a 3424 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2066 2185 3.2E-15 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS06445 20c294986a32bd538af65509e485668a 3424 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 410 523 1.8E-14 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS06445 20c294986a32bd538af65509e485668a 3424 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2212 2508 6.8E-97 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS06445 20c294986a32bd538af65509e485668a 3424 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 551 840 1.5E-111 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS06445 20c294986a32bd538af65509e485668a 3424 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2993 3170 3.9E-50 T 29-03-2018 SMALA_RS06445 20c294986a32bd538af65509e485668a 3424 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1319 1496 3.8E-51 T 29-03-2018 SMALA_RS06445 20c294986a32bd538af65509e485668a 3424 Pfam PF00550 Phosphopantetheine attachment site 1598 1663 6.5E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS06445 20c294986a32bd538af65509e485668a 3424 Pfam PF00550 Phosphopantetheine attachment site 3275 3340 2.6E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS06445 20c294986a32bd538af65509e485668a 3424 Pfam PF00698 Acyl transferase domain 2211 2525 4.5E-73 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS06445 20c294986a32bd538af65509e485668a 3424 Pfam PF00698 Acyl transferase domain 549 859 2.6E-85 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS06445 20c294986a32bd538af65509e485668a 3424 SMART SM00825 Beta-ketoacyl synthase 36 461 3.1E-213 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS06445 20c294986a32bd538af65509e485668a 3424 SMART SM00825 Beta-ketoacyl synthase 1692 2116 1.4E-223 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS06445 20c294986a32bd538af65509e485668a 3424 SUPERFAMILY SSF55048 2335 2397 2.88E-8 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS06445 20c294986a32bd538af65509e485668a 3424 SUPERFAMILY SSF52151 736 829 2.49E-65 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS06445 20c294986a32bd538af65509e485668a 3424 SUPERFAMILY SSF52151 547 676 2.49E-65 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS06445 20c294986a32bd538af65509e485668a 3424 SUPERFAMILY SSF47336 1591 1705 3.27E-25 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS06445 20c294986a32bd538af65509e485668a 3424 Gene3D G3DSA:1.10.1200.10 1590 1688 1.2E-21 T 29-03-2018 SMALA_RS06445 20c294986a32bd538af65509e485668a 3424 Gene3D G3DSA:1.10.1200.10 3265 3403 1.2E-19 T 29-03-2018 SMALA_RS06445 20c294986a32bd538af65509e485668a 3424 SUPERFAMILY SSF51735 1109 1308 1.85E-15 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS06445 20c294986a32bd538af65509e485668a 3424 SUPERFAMILY SSF52151 2404 2501 7.32E-65 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS06445 20c294986a32bd538af65509e485668a 3424 SUPERFAMILY SSF52151 2208 2337 7.32E-65 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS06445 20c294986a32bd538af65509e485668a 3424 Pfam PF08659 KR domain 2993 3168 2.5E-58 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS06445 20c294986a32bd538af65509e485668a 3424 Pfam PF08659 KR domain 1319 1494 1.8E-58 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS06445 20c294986a32bd538af65509e485668a 3424 SUPERFAMILY SSF47336 3266 3352 3.4E-20 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS06445 20c294986a32bd538af65509e485668a 3424 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1690 1940 2.4E-91 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS06445 20c294986a32bd538af65509e485668a 3424 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 284 2.6E-89 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS06445 20c294986a32bd538af65509e485668a 3424 SMART SM01294 3273 3340 1.9E-5 T 29-03-2018 SMALA_RS06445 20c294986a32bd538af65509e485668a 3424 SMART SM01294 1597 1664 4.4E-5 T 29-03-2018 SMALA_RS06445 20c294986a32bd538af65509e485668a 3424 Gene3D G3DSA:3.40.47.10 26 296 6.6E-83 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS06445 20c294986a32bd538af65509e485668a 3424 Gene3D G3DSA:3.40.47.10 1689 1952 1.1E-85 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS06445 20c294986a32bd538af65509e485668a 3424 Gene3D G3DSA:3.10.129.10 905 1021 2.9E-8 T 29-03-2018 SMALA_RS06445 20c294986a32bd538af65509e485668a 3424 Gene3D G3DSA:3.10.129.10 2577 2697 4.2E-9 T 29-03-2018 SMALA_RS06445 20c294986a32bd538af65509e485668a 3424 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 292 407 5.9E-44 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS06445 20c294986a32bd538af65509e485668a 3424 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1948 2063 1.2E-43 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS06445 20c294986a32bd538af65509e485668a 3424 Gene3D G3DSA:3.40.366.10 729 850 4.4E-22 T 29-03-2018 SMALA_RS06445 20c294986a32bd538af65509e485668a 3424 SMART SM00823 Phosphopantetheine attachment site 1596 1668 1.2E-31 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS06445 20c294986a32bd538af65509e485668a 3424 SMART SM00823 Phosphopantetheine attachment site 3272 3344 3.6E-28 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS06445 20c294986a32bd538af65509e485668a 3424 Gene3D G3DSA:3.40.366.10 2198 2513 1.1E-72 T 29-03-2018 SMALA_RS06445 20c294986a32bd538af65509e485668a 3424 Gene3D G3DSA:3.40.47.10 299 459 5.1E-62 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS06445 20c294986a32bd538af65509e485668a 3424 Gene3D G3DSA:3.40.47.10 1955 2114 9.3E-63 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS06445 20c294986a32bd538af65509e485668a 3424 SUPERFAMILY SSF51735 2992 3221 1.25E-40 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS06445 20c294986a32bd538af65509e485668a 3424 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 197 213 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS06445 20c294986a32bd538af65509e485668a 3424 Gene3D G3DSA:3.40.366.10 547 677 1.9E-38 T 29-03-2018 SMALA_RS33985 8e23861a440033246da966b593b6a7e1 646 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 118 412 2.0E-29 T 29-03-2018 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 SMALA_RS33985 8e23861a440033246da966b593b6a7e1 646 ProSitePatterns PS00659 Glycosyl hydrolases family 5 signature. 231 240 - T 29-03-2018 IPR018087 Glycoside hydrolase, family 5, conserved site GO:0004553|GO:0005975 SMALA_RS33985 8e23861a440033246da966b593b6a7e1 646 Gene3D G3DSA:3.20.20.80 53 442 3.1E-43 T 29-03-2018 SMALA_RS33985 8e23861a440033246da966b593b6a7e1 646 SUPERFAMILY SSF51445 58 429 7.75E-44 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS28460 a549c667743ad0dd1951a9681774b8a3 174 Gene3D G3DSA:3.30.300.70 1 82 1.5E-26 T 29-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal SMALA_RS28460 a549c667743ad0dd1951a9681774b8a3 174 SUPERFAMILY SSF75420 3 85 1.09E-19 T 29-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal SMALA_RS28460 a549c667743ad0dd1951a9681774b8a3 174 Pfam PF17384 RimP C-terminal SH3 domain 88 155 3.7E-13 T 29-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal SMALA_RS28460 a549c667743ad0dd1951a9681774b8a3 174 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 7 155 23.2 T 29-03-2018 IPR003728 Ribosome maturation factor RimP GO:0042274 SMALA_RS28460 a549c667743ad0dd1951a9681774b8a3 174 Pfam PF02576 RimP N-terminal domain 12 85 3.0E-22 T 29-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal SMALA_RS26295 5c05547a7155078e0dd812bb167534d2 264 Gene3D G3DSA:1.10.10.10 18 96 8.0E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS26295 5c05547a7155078e0dd812bb167534d2 264 SMART SM00866 114 254 1.5E-42 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMALA_RS26295 5c05547a7155078e0dd812bb167534d2 264 SUPERFAMILY SSF46785 28 98 1.33E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS26295 5c05547a7155078e0dd812bb167534d2 264 Pfam PF00392 Bacterial regulatory proteins, gntR family 45 94 5.0E-17 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS26295 5c05547a7155078e0dd812bb167534d2 264 Pfam PF07702 UTRA domain 114 254 6.4E-42 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMALA_RS26295 5c05547a7155078e0dd812bb167534d2 264 Gene3D G3DSA:3.40.1410.10 98 264 1.3E-47 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMALA_RS26295 5c05547a7155078e0dd812bb167534d2 264 SUPERFAMILY SSF64288 82 261 3.93E-54 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMALA_RS26295 5c05547a7155078e0dd812bb167534d2 264 SMART SM00345 37 94 1.4E-15 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS26295 5c05547a7155078e0dd812bb167534d2 264 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 68 84 2.8E-8 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS26295 5c05547a7155078e0dd812bb167534d2 264 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 54 68 2.8E-8 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS06330 868e8be349539bdfcf197caf67870048 308 SUPERFAMILY SSF51445 41 282 7.28E-63 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS06330 868e8be349539bdfcf197caf67870048 308 ProSitePatterns PS01095 Chitinases family 18 active site. 161 169 - T 29-03-2018 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 SMALA_RS06330 868e8be349539bdfcf197caf67870048 308 Pfam PF00704 Glycosyl hydrolases family 18 76 256 2.2E-17 T 29-03-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 SMALA_RS06330 868e8be349539bdfcf197caf67870048 308 Gene3D G3DSA:3.20.20.80 49 307 1.5E-37 T 29-03-2018 SMALA_RS06330 868e8be349539bdfcf197caf67870048 308 PIRSF PIRSF001103 1 308 5.3E-139 T 29-03-2018 IPR016289 Endo-beta-N-acetylglucosaminidase GO:0005576|GO:0033925 KEGG: 00511+3.2.1.96 SMALA_RS24310 62343f627347d91364075dd1e907f20a 613 Gene3D G3DSA:3.30.450.20 14 115 0.0018 T 29-03-2018 SMALA_RS24310 62343f627347d91364075dd1e907f20a 613 SUPERFAMILY SSF81606 416 551 7.85E-5 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS24310 62343f627347d91364075dd1e907f20a 613 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 359 552 2.3E-36 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS24310 62343f627347d91364075dd1e907f20a 613 Gene3D G3DSA:3.30.450.40 116 308 1.8E-15 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS24310 62343f627347d91364075dd1e907f20a 613 SUPERFAMILY SSF55785 17 104 6.28E-5 T 29-03-2018 IPR000014 PAS domain SMALA_RS24310 62343f627347d91364075dd1e907f20a 613 Gene3D G3DSA:3.60.40.10 309 553 8.6E-25 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS24310 62343f627347d91364075dd1e907f20a 613 SMART SM00331 333 553 4.0E-35 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS00770 82a2d6430a831db39fa01707dcbd873a 489 Pfam PF00206 Lyase 36 365 3.2E-95 T 29-03-2018 IPR022761 Fumarate lyase, N-terminal SMALA_RS00770 82a2d6430a831db39fa01707dcbd873a 489 Gene3D G3DSA:1.10.275.10 26 161 3.0E-57 T 29-03-2018 IPR024083 Fumarase/histidase, N-terminal SMALA_RS00770 82a2d6430a831db39fa01707dcbd873a 489 Gene3D G3DSA:1.10.40.30 439 485 6.9E-20 T 29-03-2018 SMALA_RS00770 82a2d6430a831db39fa01707dcbd873a 489 ProSitePatterns PS00163 Fumarate lyases signature. 341 350 - T 29-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 SMALA_RS00770 82a2d6430a831db39fa01707dcbd873a 489 Hamap MF_00743 Fumarate hydratase class II [fumC]. 28 486 78.084 T 29-03-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 SMALA_RS00770 82a2d6430a831db39fa01707dcbd873a 489 Pfam PF10415 Fumarase C C-terminus 432 484 3.2E-19 T 29-03-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 SMALA_RS00770 82a2d6430a831db39fa01707dcbd873a 489 SUPERFAMILY SSF48557 29 483 1.88E-142 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 SMALA_RS00770 82a2d6430a831db39fa01707dcbd873a 489 Gene3D G3DSA:1.20.200.10 162 438 1.1E-76 T 29-03-2018 SMALA_RS00770 82a2d6430a831db39fa01707dcbd873a 489 PRINTS PR00149 Fumarate lyase superfamily signature 341 357 1.4E-29 T 29-03-2018 IPR000362 Fumarate lyase family SMALA_RS00770 82a2d6430a831db39fa01707dcbd873a 489 PRINTS PR00149 Fumarate lyase superfamily signature 158 176 1.4E-29 T 29-03-2018 IPR000362 Fumarate lyase family SMALA_RS00770 82a2d6430a831db39fa01707dcbd873a 489 PRINTS PR00149 Fumarate lyase superfamily signature 295 322 1.4E-29 T 29-03-2018 IPR000362 Fumarate lyase family SMALA_RS00770 82a2d6430a831db39fa01707dcbd873a 489 PRINTS PR00149 Fumarate lyase superfamily signature 204 222 1.4E-29 T 29-03-2018 IPR000362 Fumarate lyase family SMALA_RS06035 d14a8c4c143442ec0b29ff62ddc25d4d 284 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 277 2.8E-15 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS06035 d14a8c4c143442ec0b29ff62ddc25d4d 284 Gene3D G3DSA:1.10.3720.10 19 274 4.6E-43 T 29-03-2018 SMALA_RS06035 d14a8c4c143442ec0b29ff62ddc25d4d 284 SUPERFAMILY SSF161098 16 284 4.06E-66 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS19330 c43a99c9d4e21f07358f744d860e7efb 149 SUPERFAMILY SSF48619 30 149 2.59E-38 T 29-03-2018 IPR016090 Phospholipase A2 domain GO:0004623|GO:0006644|GO:0050482 KEGG: 00564+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 SMALA_RS19330 c43a99c9d4e21f07358f744d860e7efb 149 Pfam PF09056 Prokaryotic phospholipase A2 45 149 9.4E-34 T 29-03-2018 IPR015141 Phospholipase A2, prokaryotic/fungal SMALA_RS19330 c43a99c9d4e21f07358f744d860e7efb 149 Gene3D G3DSA:1.20.90.10 41 149 2.7E-31 T 29-03-2018 IPR016090 Phospholipase A2 domain GO:0004623|GO:0006644|GO:0050482 KEGG: 00564+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 SMALA_RS18870 e6fe9ca03ac378415b7bb77556328f2e 458 Gene3D G3DSA:3.40.50.300 125 378 3.0E-15 T 29-03-2018 SMALA_RS18870 e6fe9ca03ac378415b7bb77556328f2e 458 Pfam PF01580 FtsK/SpoIIIE family 152 339 6.3E-25 T 29-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 SMALA_RS18870 e6fe9ca03ac378415b7bb77556328f2e 458 SUPERFAMILY SSF52540 151 381 5.78E-18 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS05770 8bf22f4731931aadb6bb406faa600b67 240 Gene3D G3DSA:1.10.10.10 136 214 8.0E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS05770 8bf22f4731931aadb6bb406faa600b67 240 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 1.3E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS05770 8bf22f4731931aadb6bb406faa600b67 240 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 1.3E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS05770 8bf22f4731931aadb6bb406faa600b67 240 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 1.3E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS05770 8bf22f4731931aadb6bb406faa600b67 240 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 208 2.2E-16 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS05770 8bf22f4731931aadb6bb406faa600b67 240 Gene3D G3DSA:3.40.50.2300 2 135 1.0E-34 T 29-03-2018 SMALA_RS05770 8bf22f4731931aadb6bb406faa600b67 240 SMART SM00448 3 117 6.1E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS05770 8bf22f4731931aadb6bb406faa600b67 240 SUPERFAMILY SSF46894 147 215 7.48E-21 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS05770 8bf22f4731931aadb6bb406faa600b67 240 SUPERFAMILY SSF52172 2 136 7.83E-32 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS05770 8bf22f4731931aadb6bb406faa600b67 240 SMART SM00421 152 209 3.5E-19 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS05770 8bf22f4731931aadb6bb406faa600b67 240 Pfam PF00072 Response regulator receiver domain 5 117 1.8E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS10950 5afbdcfa55c60c39649d5d4e327315a8 584 Gene3D G3DSA:3.60.110.10 1 263 4.5E-56 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMALA_RS10950 5afbdcfa55c60c39649d5d4e327315a8 584 ProSitePatterns PS00920 Nitrilases / cyanide hydratase signature 1. 36 51 - T 29-03-2018 IPR000132 Nitrilase/cyanide hydratase, conserved site GO:0016810 SMALA_RS10950 5afbdcfa55c60c39649d5d4e327315a8 584 Gene3D G3DSA:3.40.50.620 306 584 3.8E-61 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS10950 5afbdcfa55c60c39649d5d4e327315a8 584 SUPERFAMILY SSF52402 301 564 1.65E-70 T 29-03-2018 SMALA_RS10950 5afbdcfa55c60c39649d5d4e327315a8 584 PIRSF PIRSF006630 1 584 8.0E-212 T 29-03-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 SMALA_RS10950 5afbdcfa55c60c39649d5d4e327315a8 584 Pfam PF00795 Carbon-nitrogen hydrolase 5 258 3.9E-21 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMALA_RS10950 5afbdcfa55c60c39649d5d4e327315a8 584 TIGRFAM TIGR00552 nadE: NAD+ synthetase 316 559 4.1E-55 T 29-03-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 SMALA_RS10950 5afbdcfa55c60c39649d5d4e327315a8 584 Pfam PF02540 NAD synthase 309 556 1.1E-66 T 29-03-2018 IPR022310 NAD/GMP synthase SMALA_RS10950 5afbdcfa55c60c39649d5d4e327315a8 584 SUPERFAMILY SSF56317 3 278 3.01E-53 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMALA_RS41685 5c5dadf7c5f983df392ea0f1bc37945a 351 ProSitePatterns PS00356 LacI-type HTH domain signature. 17 35 - T 29-03-2018 SMALA_RS41685 5c5dadf7c5f983df392ea0f1bc37945a 351 Gene3D G3DSA:1.10.10.10 3 30 0.0087 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS41685 5c5dadf7c5f983df392ea0f1bc37945a 351 SUPERFAMILY SSF53822 84 322 3.14E-46 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SMALA_RS41685 5c5dadf7c5f983df392ea0f1bc37945a 351 Pfam PF13377 Periplasmic binding protein-like domain 186 343 3.0E-30 T 29-03-2018 SMALA_RS41685 5c5dadf7c5f983df392ea0f1bc37945a 351 Gene3D G3DSA:3.40.50.2300 194 324 8.8E-34 T 29-03-2018 SMALA_RS41685 5c5dadf7c5f983df392ea0f1bc37945a 351 SMART SM00354 14 84 6.8E-20 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS41685 5c5dadf7c5f983df392ea0f1bc37945a 351 Gene3D G3DSA:1.10.260.40 31 67 3.9E-22 T 29-03-2018 SMALA_RS41685 5c5dadf7c5f983df392ea0f1bc37945a 351 Pfam PF00356 Bacterial regulatory proteins, lacI family 16 61 7.3E-17 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS41685 5c5dadf7c5f983df392ea0f1bc37945a 351 Gene3D G3DSA:3.40.50.2300 68 193 3.6E-26 T 29-03-2018 SMALA_RS41685 5c5dadf7c5f983df392ea0f1bc37945a 351 SUPERFAMILY SSF47413 15 72 2.46E-16 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS20215 0f90ce9d4bedb188c65890ff86a7364f 519 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 257 363 7.1E-10 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS20215 0f90ce9d4bedb188c65890ff86a7364f 519 SUPERFAMILY SSF55874 240 364 1.83E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS20215 0f90ce9d4bedb188c65890ff86a7364f 519 Gene3D G3DSA:3.30.565.10 64 363 8.0E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS20215 0f90ce9d4bedb188c65890ff86a7364f 519 SMART SM00387 254 365 2.2E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS36350 c8748d133adc636210aefc344ef25a67 258 SMART SM00987 63 241 1.4E-29 T 29-03-2018 SMALA_RS36350 c8748d133adc636210aefc344ef25a67 258 SMART SM00986 63 241 1.4E-29 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SMALA_RS36350 c8748d133adc636210aefc344ef25a67 258 Pfam PF03167 Uracil DNA glycosylase superfamily 63 241 5.1E-29 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SMALA_RS36350 c8748d133adc636210aefc344ef25a67 258 SUPERFAMILY SSF52141 31 245 8.18E-43 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SMALA_RS36350 c8748d133adc636210aefc344ef25a67 258 Gene3D G3DSA:3.40.470.10 19 250 1.7E-56 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SMALA_RS32450 8924495c4eb6f27f2cc4eec56c8f945b 183 Gene3D G3DSA:3.30.1360.40 104 175 3.6E-28 T 29-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 SMALA_RS32450 8924495c4eb6f27f2cc4eec56c8f945b 183 SUPERFAMILY SSF55252 112 177 3.14E-18 T 29-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 SMALA_RS32450 8924495c4eb6f27f2cc4eec56c8f945b 183 TIGRFAM TIGR01529 argR_whole: arginine repressor 25 178 1.7E-43 T 29-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 SMALA_RS32450 8924495c4eb6f27f2cc4eec56c8f945b 183 Pfam PF01316 Arginine repressor, DNA binding domain 22 89 4.4E-25 T 29-03-2018 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 SMALA_RS32450 8924495c4eb6f27f2cc4eec56c8f945b 183 Hamap MF_00173 Arginine repressor [argR]. 1 182 54.87 T 29-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 SMALA_RS32450 8924495c4eb6f27f2cc4eec56c8f945b 183 Pfam PF02863 Arginine repressor, C-terminal domain 112 175 2.9E-23 T 29-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 SMALA_RS32450 8924495c4eb6f27f2cc4eec56c8f945b 183 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 122 157 1.0E-12 T 29-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 SMALA_RS32450 8924495c4eb6f27f2cc4eec56c8f945b 183 SUPERFAMILY SSF46785 21 89 2.72E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS32450 8924495c4eb6f27f2cc4eec56c8f945b 183 Gene3D G3DSA:1.10.10.10 15 88 7.8E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS32450 8924495c4eb6f27f2cc4eec56c8f945b 183 PRINTS PR01467 Bacterial arginine repressor signature 41 54 1.8E-26 T 29-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 SMALA_RS32450 8924495c4eb6f27f2cc4eec56c8f945b 183 PRINTS PR01467 Bacterial arginine repressor signature 118 131 1.8E-26 T 29-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 SMALA_RS32450 8924495c4eb6f27f2cc4eec56c8f945b 183 PRINTS PR01467 Bacterial arginine repressor signature 57 72 1.8E-26 T 29-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 SMALA_RS32450 8924495c4eb6f27f2cc4eec56c8f945b 183 PRINTS PR01467 Bacterial arginine repressor signature 148 163 1.8E-26 T 29-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 SMALA_RS26100 b611d7d1fdb1764b6912a7d1d3e28f27 364 SMART SM00228 122 198 0.002 T 29-03-2018 IPR001478 PDZ domain GO:0005515 SMALA_RS26100 b611d7d1fdb1764b6912a7d1d3e28f27 364 Pfam PF13180 PDZ domain 136 194 2.9E-9 T 29-03-2018 IPR001478 PDZ domain GO:0005515 SMALA_RS26100 b611d7d1fdb1764b6912a7d1d3e28f27 364 SUPERFAMILY SSF54211 215 347 3.03E-20 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SMALA_RS26100 b611d7d1fdb1764b6912a7d1d3e28f27 364 Gene3D G3DSA:3.30.230.10 39 363 1.2E-42 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SMALA_RS26100 b611d7d1fdb1764b6912a7d1d3e28f27 364 SUPERFAMILY SSF50156 139 199 3.33E-10 T 29-03-2018 IPR001478 PDZ domain GO:0005515 SMALA_RS26100 b611d7d1fdb1764b6912a7d1d3e28f27 364 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 255 345 2.5E-8 T 29-03-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 SMALA_RS18110 8fff7b370ace5b3cb14d26e21f81ba22 201 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 22 198 2.9E-72 T 29-03-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 SMALA_RS18110 8fff7b370ace5b3cb14d26e21f81ba22 201 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 17 199 41.829 T 29-03-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 SMALA_RS18110 8fff7b370ace5b3cb14d26e21f81ba22 201 Pfam PF01227 GTP cyclohydrolase I 22 198 3.3E-77 T 29-03-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 SMALA_RS18110 8fff7b370ace5b3cb14d26e21f81ba22 201 Gene3D G3DSA:1.10.286.10 19 67 4.7E-24 T 29-03-2018 SMALA_RS18110 8fff7b370ace5b3cb14d26e21f81ba22 201 Gene3D G3DSA:3.30.1130.10 68 201 3.8E-58 T 29-03-2018 SMALA_RS18110 8fff7b370ace5b3cb14d26e21f81ba22 201 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 77 93 - T 29-03-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 SMALA_RS18110 8fff7b370ace5b3cb14d26e21f81ba22 201 SUPERFAMILY SSF55620 16 198 1.56E-76 T 29-03-2018 SMALA_RS18110 8fff7b370ace5b3cb14d26e21f81ba22 201 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 127 137 - T 29-03-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 SMALA_RS11280 90f8fcfd10a081b876c347c9b23c99d3 356 SUPERFAMILY SSF53659 6 356 8.46E-118 T 29-03-2018 SMALA_RS11280 90f8fcfd10a081b876c347c9b23c99d3 356 TIGRFAM TIGR02089 TTC: tartrate dehydrogenase 8 355 1.4E-162 T 29-03-2018 IPR011829 Tartrate dehydrogenase GO:0016616|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.93|KEGG: 00650+1.1.1.83 SMALA_RS11280 90f8fcfd10a081b876c347c9b23c99d3 356 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 245 264 - T 29-03-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 SMALA_RS11280 90f8fcfd10a081b876c347c9b23c99d3 356 SMART SM01329 10 352 7.2E-172 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 SMALA_RS11280 90f8fcfd10a081b876c347c9b23c99d3 356 Gene3D G3DSA:3.40.718.10 2 356 4.7E-118 T 29-03-2018 SMALA_RS11280 90f8fcfd10a081b876c347c9b23c99d3 356 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 11 351 6.3E-89 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 SMALA_RS04315 f157ddb8749151ad071d13bd9cd6f519 370 Pfam PF13378 Enolase C-terminal domain-like 142 343 6.7E-40 T 29-03-2018 IPR029065 Enolase C-terminal domain-like SMALA_RS04315 f157ddb8749151ad071d13bd9cd6f519 370 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 6 118 1.0E-9 T 29-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain SMALA_RS04315 f157ddb8749151ad071d13bd9cd6f519 370 Gene3D G3DSA:3.20.20.120 121 345 1.6E-54 T 29-03-2018 IPR029065 Enolase C-terminal domain-like SMALA_RS04315 f157ddb8749151ad071d13bd9cd6f519 370 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 184 215 - T 29-03-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 SMALA_RS04315 f157ddb8749151ad071d13bd9cd6f519 370 SMART SM00922 138 234 4.0E-19 T 29-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal SMALA_RS04315 f157ddb8749151ad071d13bd9cd6f519 370 SUPERFAMILY SSF51604 107 347 5.9E-55 T 29-03-2018 IPR029065 Enolase C-terminal domain-like SMALA_RS04315 f157ddb8749151ad071d13bd9cd6f519 370 SUPERFAMILY SSF54826 4 118 8.2E-17 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMALA_RS04315 f157ddb8749151ad071d13bd9cd6f519 370 Gene3D G3DSA:3.30.390.10 1 120 6.8E-19 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMALA_RS30370 a5a5e87683cb52cb2ad1d117ac44c46b 617 Pfam PF13672 Protein phosphatase 2C 350 596 1.6E-20 T 29-03-2018 SMALA_RS30370 a5a5e87683cb52cb2ad1d117ac44c46b 617 Gene3D G3DSA:3.60.40.10 338 615 9.1E-7 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS21840 89d9168a7cd4bc4e9a2f890d7775b8d9 334 SUPERFAMILY SSF51569 6 332 1.2E-130 T 29-03-2018 SMALA_RS21840 89d9168a7cd4bc4e9a2f890d7775b8d9 334 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 304 323 3.5E-54 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 SMALA_RS21840 89d9168a7cd4bc4e9a2f890d7775b8d9 334 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 129 143 3.5E-54 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 SMALA_RS21840 89d9168a7cd4bc4e9a2f890d7775b8d9 334 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 274 289 3.5E-54 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 SMALA_RS21840 89d9168a7cd4bc4e9a2f890d7775b8d9 334 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 160 179 3.5E-54 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 SMALA_RS21840 89d9168a7cd4bc4e9a2f890d7775b8d9 334 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 198 217 3.5E-54 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 SMALA_RS21840 89d9168a7cd4bc4e9a2f890d7775b8d9 334 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 249 265 3.5E-54 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 SMALA_RS21840 89d9168a7cd4bc4e9a2f890d7775b8d9 334 PIRSF PIRSF001415 2 333 2.3E-144 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 SMALA_RS21840 89d9168a7cd4bc4e9a2f890d7775b8d9 334 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 249 261 - T 29-03-2018 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 SMALA_RS21840 89d9168a7cd4bc4e9a2f890d7775b8d9 334 Gene3D G3DSA:3.20.20.70 1 334 2.8E-146 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS21840 89d9168a7cd4bc4e9a2f890d7775b8d9 334 Pfam PF00490 Delta-aminolevulinic acid dehydratase 11 328 6.2E-137 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 SMALA_RS21840 89d9168a7cd4bc4e9a2f890d7775b8d9 334 SMART SM01004 8 330 3.8E-212 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 SMALA_RS21950 c5332051f5cd54c0b0b87c329c9a18f2 395 SUPERFAMILY SSF88713 141 374 1.33E-24 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 SMALA_RS21950 c5332051f5cd54c0b0b87c329c9a18f2 395 SUPERFAMILY SSF88713 67 111 1.33E-24 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 SMALA_RS21950 c5332051f5cd54c0b0b87c329c9a18f2 395 Gene3D G3DSA:3.20.20.370 56 380 2.8E-36 T 29-03-2018 SMALA_RS07450 afe2705e5bc56f065ab1aa6784731916 816 SUPERFAMILY SSF52540 541 602 1.67E-15 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS07450 afe2705e5bc56f065ab1aa6784731916 816 SUPERFAMILY SSF52540 643 785 1.67E-15 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS07450 afe2705e5bc56f065ab1aa6784731916 816 Pfam PF14490 Helix-hairpin-helix containing domain 210 293 4.2E-10 T 29-03-2018 IPR029493 RecD helicase-like helix-hairpin-helix domain SMALA_RS07450 afe2705e5bc56f065ab1aa6784731916 816 Gene3D G3DSA:3.40.50.300 135 573 7.9E-4 T 29-03-2018 SMALA_RS07450 afe2705e5bc56f065ab1aa6784731916 816 Gene3D G3DSA:3.40.50.300 574 793 6.9E-8 T 29-03-2018 SMALA_RS06725 2b12a3823bf5a2842238026ea54f4dd7 466 SUPERFAMILY SSF103473 64 462 6.8E-44 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS06725 2b12a3823bf5a2842238026ea54f4dd7 466 Pfam PF05977 Transmembrane secretion effector 64 453 1.8E-28 T 29-03-2018 IPR010290 Transmembrane secretion effector SMALA_RS06725 2b12a3823bf5a2842238026ea54f4dd7 466 Gene3D G3DSA:1.20.1250.20 58 258 4.0E-17 T 29-03-2018 SMALA_RS06725 2b12a3823bf5a2842238026ea54f4dd7 466 Gene3D G3DSA:1.20.1250.20 266 463 5.3E-18 T 29-03-2018 SMALA_RS18955 252273eb798f122da3e7ac72ad40c857 152 SUPERFAMILY SSF55961 1 145 7.13E-24 T 29-03-2018 SMALA_RS18955 252273eb798f122da3e7ac72ad40c857 152 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 10 123 9.9E-13 T 29-03-2018 IPR005031 Coenzyme Q-binding protein COQ10, START domain Reactome: R-HSA-611105 SMALA_RS18955 252273eb798f122da3e7ac72ad40c857 152 Gene3D G3DSA:3.30.530.20 1 148 1.3E-19 T 29-03-2018 IPR023393 START-like domain SMALA_RS41150 ae440f52abb09938ee3c111b1648dd19 729 SUPERFAMILY SSF48230 51 382 2.44E-48 T 29-03-2018 IPR008929 Chondroitin AC/alginate lyase Reactome: R-HSA-2022923 SMALA_RS41150 ae440f52abb09938ee3c111b1648dd19 729 Gene3D G3DSA:1.50.10.100 69 374 2.1E-50 T 29-03-2018 SMALA_RS41150 ae440f52abb09938ee3c111b1648dd19 729 Gene3D G3DSA:2.60.220.10 624 725 3.3E-24 T 29-03-2018 SMALA_RS41150 ae440f52abb09938ee3c111b1648dd19 729 Pfam PF08124 Polysaccharide lyase family 8, N terminal alpha-helical domain 92 307 4.9E-16 T 29-03-2018 IPR012970 Polysaccharide lyase 8, N-terminal alpha-helical SMALA_RS41150 ae440f52abb09938ee3c111b1648dd19 729 SUPERFAMILY SSF49863 628 725 4.51E-18 T 29-03-2018 IPR011071 Polysaccharide lyase family 8-like, C-terminal GO:0005975 SMALA_RS41150 ae440f52abb09938ee3c111b1648dd19 729 Pfam PF02278 Polysaccharide lyase family 8, super-sandwich domain 376 614 8.1E-50 T 29-03-2018 IPR003159 Polysaccharide lyase family 8, central domain GO:0005576|GO:0016829 SMALA_RS41150 ae440f52abb09938ee3c111b1648dd19 729 Gene3D G3DSA:2.70.98.10 375 623 4.3E-61 T 29-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 SMALA_RS41150 ae440f52abb09938ee3c111b1648dd19 729 Pfam PF02884 Polysaccharide lyase family 8, C-terminal beta-sandwich domain 629 693 4.1E-17 T 29-03-2018 IPR004103 Polysaccharide lyase family 8, C-terminal GO:0005576|GO:0016829 SMALA_RS41150 ae440f52abb09938ee3c111b1648dd19 729 SUPERFAMILY SSF74650 374 634 1.41E-51 T 29-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 SMALA_RS19550 323c44e33683947bd340776589f24fe3 212 PRINTS PR01576 Peptide deformylase signature 130 148 2.1E-34 T 29-03-2018 IPR023635 Peptide deformylase SMALA_RS19550 323c44e33683947bd340776589f24fe3 212 PRINTS PR01576 Peptide deformylase signature 149 178 2.1E-34 T 29-03-2018 IPR023635 Peptide deformylase SMALA_RS19550 323c44e33683947bd340776589f24fe3 212 PRINTS PR01576 Peptide deformylase signature 118 129 2.1E-34 T 29-03-2018 IPR023635 Peptide deformylase SMALA_RS19550 323c44e33683947bd340776589f24fe3 212 PRINTS PR01576 Peptide deformylase signature 56 85 2.1E-34 T 29-03-2018 IPR023635 Peptide deformylase SMALA_RS19550 323c44e33683947bd340776589f24fe3 212 Pfam PF01327 Polypeptide deformylase 26 181 6.3E-46 T 29-03-2018 IPR023635 Peptide deformylase SMALA_RS19550 323c44e33683947bd340776589f24fe3 212 SUPERFAMILY SSF56420 22 188 7.07E-52 T 29-03-2018 IPR023635 Peptide deformylase SMALA_RS19550 323c44e33683947bd340776589f24fe3 212 Hamap MF_00163 Peptide deformylase [def]. 24 191 28.546 T 29-03-2018 IPR023635 Peptide deformylase SMALA_RS19550 323c44e33683947bd340776589f24fe3 212 Gene3D G3DSA:3.90.45.10 13 203 8.5E-57 T 29-03-2018 IPR023635 Peptide deformylase SMALA_RS19550 323c44e33683947bd340776589f24fe3 212 PIRSF PIRSF004749 12 205 1.4E-43 T 29-03-2018 IPR023635 Peptide deformylase SMALA_RS19550 323c44e33683947bd340776589f24fe3 212 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 28 187 2.8E-39 T 29-03-2018 IPR023635 Peptide deformylase SMALA_RS21705 04185f5ee67f22693cae91f3378985e1 741 Pfam PF13360 PQQ-like domain 511 708 2.6E-11 T 29-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat SMALA_RS21705 04185f5ee67f22693cae91f3378985e1 741 SMART SM00220 14 261 1.9E-40 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMALA_RS21705 04185f5ee67f22693cae91f3378985e1 741 SUPERFAMILY SSF56112 11 261 3.86E-59 T 29-03-2018 IPR011009 Protein kinase-like domain SMALA_RS21705 04185f5ee67f22693cae91f3378985e1 741 SUPERFAMILY SSF50998 624 706 2.2E-11 T 29-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily SMALA_RS21705 04185f5ee67f22693cae91f3378985e1 741 Gene3D G3DSA:2.140.10.10 352 594 8.4E-4 T 29-03-2018 SMALA_RS21705 04185f5ee67f22693cae91f3378985e1 741 Gene3D G3DSA:2.140.10.10 609 732 6.2E-13 T 29-03-2018 SMALA_RS21705 04185f5ee67f22693cae91f3378985e1 741 SMART SM00564 669 702 0.99 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMALA_RS21705 04185f5ee67f22693cae91f3378985e1 741 SMART SM00564 630 660 0.84 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMALA_RS21705 04185f5ee67f22693cae91f3378985e1 741 SMART SM00564 448 484 690.0 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMALA_RS21705 04185f5ee67f22693cae91f3378985e1 741 Gene3D G3DSA:1.10.510.10 97 301 4.3E-42 T 29-03-2018 SMALA_RS21705 04185f5ee67f22693cae91f3378985e1 741 SUPERFAMILY SSF50969 446 710 7.85E-6 T 29-03-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like SMALA_RS21705 04185f5ee67f22693cae91f3378985e1 741 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 20 42 - T 29-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 SMALA_RS21705 04185f5ee67f22693cae91f3378985e1 741 Pfam PF00069 Protein kinase domain 14 261 8.7E-39 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMALA_RS21705 04185f5ee67f22693cae91f3378985e1 741 Gene3D G3DSA:3.30.200.20 9 96 3.0E-12 T 29-03-2018 SMALA_RS21705 04185f5ee67f22693cae91f3378985e1 741 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 132 144 - T 29-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMALA_RS35005 efd411d1ff16f00af70ecc7a6a0f76bb 592 ProSitePatterns PS00211 ABC transporters family signature. 492 506 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS35005 efd411d1ff16f00af70ecc7a6a0f76bb 592 Gene3D G3DSA:3.40.50.300 353 586 8.7E-36 T 29-03-2018 SMALA_RS35005 efd411d1ff16f00af70ecc7a6a0f76bb 592 Pfam PF00005 ABC transporter 384 520 7.6E-9 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS35005 efd411d1ff16f00af70ecc7a6a0f76bb 592 SUPERFAMILY SSF52540 354 578 5.99E-32 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS35005 efd411d1ff16f00af70ecc7a6a0f76bb 592 Gene3D G3DSA:1.20.1560.10 12 331 1.8E-47 T 29-03-2018 SMALA_RS35005 efd411d1ff16f00af70ecc7a6a0f76bb 592 Pfam PF00664 ABC transporter transmembrane region 33 301 7.8E-27 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMALA_RS35005 efd411d1ff16f00af70ecc7a6a0f76bb 592 SUPERFAMILY SSF90123 20 331 2.22E-54 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMALA_RS29435 e0ef5c20864ebf859cddf85c6a67ad3b 364 Gene3D G3DSA:3.40.47.10 12 247 6.4E-30 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS29435 e0ef5c20864ebf859cddf85c6a67ad3b 364 SUPERFAMILY SSF53901 210 361 1.56E-10 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS29435 e0ef5c20864ebf859cddf85c6a67ad3b 364 Gene3D G3DSA:3.40.47.10 248 350 2.2E-4 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS29435 e0ef5c20864ebf859cddf85c6a67ad3b 364 SUPERFAMILY SSF53901 12 232 3.76E-29 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS29435 e0ef5c20864ebf859cddf85c6a67ad3b 364 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 13 230 1.9E-14 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS07790 89c602c91571d39baed153252045e293 266 SUPERFAMILY SSF53335 6 205 4.56E-27 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS07790 89c602c91571d39baed153252045e293 266 Gene3D G3DSA:3.40.50.150 13 266 3.8E-27 T 29-03-2018 SMALA_RS07790 89c602c91571d39baed153252045e293 266 Pfam PF13649 Methyltransferase domain 44 137 6.9E-13 T 29-03-2018 SMALA_RS05180 aeaadbbb296412132dfb25f6ea781c56 239 Gene3D G3DSA:1.10.10.10 15 90 3.9E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS05180 aeaadbbb296412132dfb25f6ea781c56 239 Gene3D G3DSA:1.20.120.530 93 238 2.8E-31 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS05180 aeaadbbb296412132dfb25f6ea781c56 239 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 60 79 5.7E-5 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMALA_RS05180 aeaadbbb296412132dfb25f6ea781c56 239 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 49 60 5.7E-5 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMALA_RS05180 aeaadbbb296412132dfb25f6ea781c56 239 SMART SM00895 100 227 2.6E-21 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS05180 aeaadbbb296412132dfb25f6ea781c56 239 SMART SM00345 31 89 2.2E-10 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS05180 aeaadbbb296412132dfb25f6ea781c56 239 Pfam PF07729 FCD domain 100 226 1.7E-25 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS05180 aeaadbbb296412132dfb25f6ea781c56 239 SUPERFAMILY SSF48008 96 232 9.68E-26 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS05180 aeaadbbb296412132dfb25f6ea781c56 239 SUPERFAMILY SSF46785 24 93 1.05E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS05180 aeaadbbb296412132dfb25f6ea781c56 239 Pfam PF00392 Bacterial regulatory proteins, gntR family 28 86 2.0E-14 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS38645 cf525f9718d73bab9b577e0b41d6968a 404 Gene3D G3DSA:3.40.50.1110 185 390 3.0E-27 T 29-03-2018 SMALA_RS38645 cf525f9718d73bab9b577e0b41d6968a 404 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 200 384 1.2E-25 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain SMALA_RS38645 cf525f9718d73bab9b577e0b41d6968a 404 SUPERFAMILY SSF52266 195 390 2.44E-45 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain SMALA_RS06230 48b06514ebc11759921d7256d3308f91 378 Pfam PF07995 Glucose / Sorbosone dehydrogenase 49 366 1.1E-46 T 29-03-2018 IPR012938 Glucose/Sorbosone dehydrogenase SMALA_RS06230 48b06514ebc11759921d7256d3308f91 378 SUPERFAMILY SSF50952 48 377 1.1E-28 T 29-03-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 SMALA_RS06230 48b06514ebc11759921d7256d3308f91 378 Gene3D G3DSA:2.120.10.30 23 378 3.9E-68 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like SMALA_RS26765 42a99953eb2aabe47a0f2080097121da 1101 Gene3D G3DSA:3.40.50.150 334 710 1.0E-22 T 29-03-2018 SMALA_RS26765 42a99953eb2aabe47a0f2080097121da 1101 SUPERFAMILY SSF53335 267 651 7.27E-31 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS26765 42a99953eb2aabe47a0f2080097121da 1101 Pfam PF02384 N-6 DNA Methylase 319 500 1.1E-8 T 29-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 SMALA_RS26765 42a99953eb2aabe47a0f2080097121da 1101 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 373 387 3.7E-9 T 29-03-2018 SMALA_RS26765 42a99953eb2aabe47a0f2080097121da 1101 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 490 502 3.7E-9 T 29-03-2018 SMALA_RS26765 42a99953eb2aabe47a0f2080097121da 1101 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 336 352 3.7E-9 T 29-03-2018 SMALA_RS01700 b3e6a84085bb333b9546b45caef1a70e 221 Pfam PF13419 Haloacid dehalogenase-like hydrolase 90 168 7.0E-7 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS01700 b3e6a84085bb333b9546b45caef1a70e 221 SUPERFAMILY SSF56784 1 219 6.51E-37 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS01700 b3e6a84085bb333b9546b45caef1a70e 221 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 181 194 7.0E-5 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMALA_RS01700 b3e6a84085bb333b9546b45caef1a70e 221 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 2 13 7.0E-5 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMALA_RS01700 b3e6a84085bb333b9546b45caef1a70e 221 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 134 150 7.0E-5 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMALA_RS01700 b3e6a84085bb333b9546b45caef1a70e 221 Gene3D G3DSA:3.40.50.1000 76 220 5.0E-15 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS06605 439f8b299d107dc015928dafb05f57d7 255 SUPERFAMILY SSF102215 5 249 1.44E-58 T 29-03-2018 IPR024087 Creatininase-like domain KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167 SMALA_RS06605 439f8b299d107dc015928dafb05f57d7 255 Gene3D G3DSA:3.40.50.10310 1 253 3.3E-65 T 29-03-2018 IPR024087 Creatininase-like domain KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167 SMALA_RS06605 439f8b299d107dc015928dafb05f57d7 255 Pfam PF02633 Creatinine amidohydrolase 8 245 3.5E-55 T 29-03-2018 IPR003785 Creatininase/formamide hydrolase KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167 SMALA_RS01945 0f5b368ad120805799e21724cd81ad92 488 SUPERFAMILY SSF53649 2 458 5.67E-111 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 SMALA_RS01945 0f5b368ad120805799e21724cd81ad92 488 Gene3D G3DSA:3.30.1120.10 384 470 1.7E-12 T 29-03-2018 SMALA_RS01945 0f5b368ad120805799e21724cd81ad92 488 Pfam PF16347 Domain of unknown function (DUF4976) 367 455 1.8E-8 T 29-03-2018 IPR032506 Domain of unknown function DUF4976 Reactome: R-HSA-2024096 SMALA_RS01945 0f5b368ad120805799e21724cd81ad92 488 ProSitePatterns PS00523 Sulfatases signature 1. 47 59 - T 29-03-2018 IPR024607 Sulfatase, conserved site SMALA_RS01945 0f5b368ad120805799e21724cd81ad92 488 Pfam PF00884 Sulfatase 2 359 3.7E-60 T 29-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 SMALA_RS01945 0f5b368ad120805799e21724cd81ad92 488 Gene3D G3DSA:3.40.720.10 2 379 1.0E-78 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 SMALA_RS29470 4d12c7edfc7953e8d16677ca5bc1b482 2627 SUPERFAMILY SSF52777 1247 1513 6.78E-64 T 29-03-2018 SMALA_RS29470 4d12c7edfc7953e8d16677ca5bc1b482 2627 SUPERFAMILY SSF47336 2035 2103 1.57E-18 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS29470 4d12c7edfc7953e8d16677ca5bc1b482 2627 SUPERFAMILY SSF52777 1064 1234 4.22E-49 T 29-03-2018 SMALA_RS29470 4d12c7edfc7953e8d16677ca5bc1b482 2627 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1002 1017 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS29470 4d12c7edfc7953e8d16677ca5bc1b482 2627 Gene3D G3DSA:3.40.50.980 1685 1837 8.9E-28 T 29-03-2018 SMALA_RS29470 4d12c7edfc7953e8d16677ca5bc1b482 2627 Gene3D G3DSA:3.30.559.10 2109 2318 1.4E-25 T 29-03-2018 SMALA_RS29470 4d12c7edfc7953e8d16677ca5bc1b482 2627 Pfam PF00501 AMP-binding enzyme 1530 1932 2.3E-89 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS29470 4d12c7edfc7953e8d16677ca5bc1b482 2627 Pfam PF00501 AMP-binding enzyme 464 869 6.9E-103 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS29470 4d12c7edfc7953e8d16677ca5bc1b482 2627 Pfam PF00550 Phosphopantetheine attachment site 981 1040 2.9E-15 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS29470 4d12c7edfc7953e8d16677ca5bc1b482 2627 Pfam PF00550 Phosphopantetheine attachment site 2043 2103 1.5E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS29470 4d12c7edfc7953e8d16677ca5bc1b482 2627 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 485 893 1.5E-137 T 29-03-2018 IPR010071 Amino acid adenylation domain SMALA_RS29470 4d12c7edfc7953e8d16677ca5bc1b482 2627 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1550 1956 1.0E-129 T 29-03-2018 IPR010071 Amino acid adenylation domain SMALA_RS29470 4d12c7edfc7953e8d16677ca5bc1b482 2627 Gene3D G3DSA:1.10.1200.10 982 1044 3.4E-25 T 29-03-2018 SMALA_RS29470 4d12c7edfc7953e8d16677ca5bc1b482 2627 Gene3D G3DSA:3.30.300.30 1927 2045 1.5E-40 T 29-03-2018 SMALA_RS29470 4d12c7edfc7953e8d16677ca5bc1b482 2627 Gene3D G3DSA:3.30.300.30 864 981 3.2E-42 T 29-03-2018 SMALA_RS29470 4d12c7edfc7953e8d16677ca5bc1b482 2627 SMART SM00823 Phosphopantetheine attachment site 2040 2108 5.7E-6 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS29470 4d12c7edfc7953e8d16677ca5bc1b482 2627 SMART SM00823 Phosphopantetheine attachment site 978 1047 4.6E-6 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS29470 4d12c7edfc7953e8d16677ca5bc1b482 2627 SMART SM01294 2041 2104 0.0019 T 29-03-2018 SMALA_RS29470 4d12c7edfc7953e8d16677ca5bc1b482 2627 Gene3D G3DSA:3.40.50.980 1521 1684 2.3E-48 T 29-03-2018 SMALA_RS29470 4d12c7edfc7953e8d16677ca5bc1b482 2627 SUPERFAMILY SSF47336 971 1043 3.01E-20 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS29470 4d12c7edfc7953e8d16677ca5bc1b482 2627 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 2448 2606 3.5E-40 T 29-03-2018 IPR010060 Non-ribosomal peptide synthase SMALA_RS29470 4d12c7edfc7953e8d16677ca5bc1b482 2627 Gene3D G3DSA:1.10.1200.10 2046 2108 4.3E-22 T 29-03-2018 SMALA_RS29470 4d12c7edfc7953e8d16677ca5bc1b482 2627 SUPERFAMILY SSF52777 189 452 5.45E-60 T 29-03-2018 SMALA_RS29470 4d12c7edfc7953e8d16677ca5bc1b482 2627 Gene3D G3DSA:2.30.38.10 1841 1922 9.5E-24 T 29-03-2018 SMALA_RS29470 4d12c7edfc7953e8d16677ca5bc1b482 2627 Gene3D G3DSA:2.30.38.10 782 859 4.8E-23 T 29-03-2018 SMALA_RS29470 4d12c7edfc7953e8d16677ca5bc1b482 2627 SUPERFAMILY SSF52777 6 204 8.12E-43 T 29-03-2018 SMALA_RS29470 4d12c7edfc7953e8d16677ca5bc1b482 2627 Gene3D G3DSA:3.30.559.10 2 200 2.0E-43 T 29-03-2018 SMALA_RS29470 4d12c7edfc7953e8d16677ca5bc1b482 2627 Gene3D G3DSA:3.40.50.980 455 604 1.5E-34 T 29-03-2018 SMALA_RS29470 4d12c7edfc7953e8d16677ca5bc1b482 2627 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1679 1690 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS29470 4d12c7edfc7953e8d16677ca5bc1b482 2627 Pfam PF13193 AMP-binding enzyme C-terminal domain 877 953 4.9E-14 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS29470 4d12c7edfc7953e8d16677ca5bc1b482 2627 Pfam PF13193 AMP-binding enzyme C-terminal domain 1940 2015 5.7E-15 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS29470 4d12c7edfc7953e8d16677ca5bc1b482 2627 SUPERFAMILY SSF52777 2118 2322 2.78E-29 T 29-03-2018 SMALA_RS29470 4d12c7edfc7953e8d16677ca5bc1b482 2627 SUPERFAMILY SSF52777 2315 2582 1.89E-31 T 29-03-2018 SMALA_RS29470 4d12c7edfc7953e8d16677ca5bc1b482 2627 SUPERFAMILY SSF56801 1488 2053 2.09E-150 T 29-03-2018 SMALA_RS29470 4d12c7edfc7953e8d16677ca5bc1b482 2627 SUPERFAMILY SSF56801 423 991 1.83E-167 T 29-03-2018 SMALA_RS29470 4d12c7edfc7953e8d16677ca5bc1b482 2627 ProSitePatterns PS00455 Putative AMP-binding domain signature. 613 624 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS29470 4d12c7edfc7953e8d16677ca5bc1b482 2627 Gene3D G3DSA:3.40.50.980 605 781 1.6E-57 T 29-03-2018 SMALA_RS29470 4d12c7edfc7953e8d16677ca5bc1b482 2627 Pfam PF00668 Condensation domain 1061 1509 5.7E-96 T 29-03-2018 IPR001242 Condensation domain SMALA_RS29470 4d12c7edfc7953e8d16677ca5bc1b482 2627 Pfam PF00668 Condensation domain 2140 2583 9.8E-45 T 29-03-2018 IPR001242 Condensation domain SMALA_RS29470 4d12c7edfc7953e8d16677ca5bc1b482 2627 Pfam PF00668 Condensation domain 8 443 3.5E-88 T 29-03-2018 IPR001242 Condensation domain SMALA_RS29470 4d12c7edfc7953e8d16677ca5bc1b482 2627 Gene3D G3DSA:3.30.559.10 1045 1259 4.8E-46 T 29-03-2018 SMALA_RS29470 4d12c7edfc7953e8d16677ca5bc1b482 2627 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2064 2079 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS01250 635fe50bacb692796e9e57ede5ee5a67 442 Gene3D G3DSA:3.30.390.10 1 136 1.0E-30 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMALA_RS01250 635fe50bacb692796e9e57ede5ee5a67 442 Gene3D G3DSA:3.20.20.120 137 410 2.6E-49 T 29-03-2018 IPR029065 Enolase C-terminal domain-like SMALA_RS01250 635fe50bacb692796e9e57ede5ee5a67 442 Pfam PF13378 Enolase C-terminal domain-like 184 401 2.1E-36 T 29-03-2018 IPR029065 Enolase C-terminal domain-like SMALA_RS01250 635fe50bacb692796e9e57ede5ee5a67 442 SUPERFAMILY SSF51604 135 411 5.53E-78 T 29-03-2018 IPR029065 Enolase C-terminal domain-like SMALA_RS01250 635fe50bacb692796e9e57ede5ee5a67 442 SMART SM00922 181 281 6.0E-18 T 29-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal SMALA_RS01250 635fe50bacb692796e9e57ede5ee5a67 442 SUPERFAMILY SSF54826 4 133 3.2E-30 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMALA_RS11110 223ab7a48133300c42c0a99b473e2078 325 SUPERFAMILY SSF81345 2 316 3.01E-83 T 29-03-2018 IPR029022 ABC transporter, BtuC-like SMALA_RS11110 223ab7a48133300c42c0a99b473e2078 325 Gene3D G3DSA:1.10.3470.10 1 323 2.8E-73 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SMALA_RS11110 223ab7a48133300c42c0a99b473e2078 325 Pfam PF01032 FecCD transport family 1 316 2.1E-95 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 SMALA_RS17220 d46c0230c69d4b4e735b28aa34d23e6a 702 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 110 1.3E-38 T 29-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SMALA_RS17220 d46c0230c69d4b4e735b28aa34d23e6a 702 Gene3D G3DSA:3.30.470.20 195 437 7.1E-98 T 29-03-2018 SMALA_RS17220 d46c0230c69d4b4e735b28aa34d23e6a 702 Gene3D G3DSA:3.30.1490.20 124 194 1.7E-14 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SMALA_RS17220 d46c0230c69d4b4e735b28aa34d23e6a 702 SUPERFAMILY SSF52440 2 113 1.15E-41 T 29-03-2018 IPR016185 Pre-ATP-grasp domain SMALA_RS17220 d46c0230c69d4b4e735b28aa34d23e6a 702 SUPERFAMILY SSF51230 622 698 5.63E-20 T 29-03-2018 IPR011053 Single hybrid motif SMALA_RS17220 d46c0230c69d4b4e735b28aa34d23e6a 702 Pfam PF00364 Biotin-requiring enzyme 634 697 5.9E-17 T 29-03-2018 IPR000089 Biotin/lipoyl attachment SMALA_RS17220 d46c0230c69d4b4e735b28aa34d23e6a 702 SUPERFAMILY SSF51246 320 433 6.28E-32 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 SMALA_RS17220 d46c0230c69d4b4e735b28aa34d23e6a 702 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 143 312 7.5E-64 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SMALA_RS17220 d46c0230c69d4b4e735b28aa34d23e6a 702 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 277 284 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SMALA_RS17220 d46c0230c69d4b4e735b28aa34d23e6a 702 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 655 672 - T 29-03-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SMALA_RS17220 d46c0230c69d4b4e735b28aa34d23e6a 702 SUPERFAMILY SSF56059 83 321 2.47E-57 T 29-03-2018 SMALA_RS17220 d46c0230c69d4b4e735b28aa34d23e6a 702 Pfam PF02785 Biotin carboxylase C-terminal domain 325 429 4.0E-28 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SMALA_RS17220 d46c0230c69d4b4e735b28aa34d23e6a 702 SMART SM00878 325 428 2.9E-42 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SMALA_RS17220 d46c0230c69d4b4e735b28aa34d23e6a 702 Gene3D G3DSA:3.40.50.20 1 123 1.8E-44 T 29-03-2018 SMALA_RS17220 d46c0230c69d4b4e735b28aa34d23e6a 702 Gene3D G3DSA:2.40.50.100 627 700 2.5E-17 T 29-03-2018 SMALA_RS10745 61aef28e5254bd74b33dea5cca268443 262 Gene3D G3DSA:2.70.220.10 64 120 0.11 T 29-03-2018 SMALA_RS10745 61aef28e5254bd74b33dea5cca268443 262 Gene3D G3DSA:3.90.75.10 121 171 4.3E-4 T 29-03-2018 SMALA_RS10745 61aef28e5254bd74b33dea5cca268443 262 Gene3D G3DSA:2.60.40.10 172 258 0.004 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS10745 61aef28e5254bd74b33dea5cca268443 262 Pfam PF16640 Bacterial Ig-like domain (group 3) 79 166 3.5E-18 T 29-03-2018 IPR032109 Bacterial Ig-like domain (group 3) SMALA_RS10745 61aef28e5254bd74b33dea5cca268443 262 Pfam PF16640 Bacterial Ig-like domain (group 3) 174 261 3.6E-18 T 29-03-2018 IPR032109 Bacterial Ig-like domain (group 3) SMALA_RS38450 9ac47ec4bc530de18cf6fd3d2cfa41f5 464 PRINTS PR00463 E-class P450 group I signature 275 301 8.0E-31 T 29-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS38450 9ac47ec4bc530de18cf6fd3d2cfa41f5 464 PRINTS PR00463 E-class P450 group I signature 306 324 8.0E-31 T 29-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS38450 9ac47ec4bc530de18cf6fd3d2cfa41f5 464 PRINTS PR00463 E-class P450 group I signature 30 49 8.0E-31 T 29-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS38450 9ac47ec4bc530de18cf6fd3d2cfa41f5 464 PRINTS PR00463 E-class P450 group I signature 346 370 8.0E-31 T 29-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS38450 9ac47ec4bc530de18cf6fd3d2cfa41f5 464 PRINTS PR00463 E-class P450 group I signature 255 272 8.0E-31 T 29-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS38450 9ac47ec4bc530de18cf6fd3d2cfa41f5 464 PRINTS PR00463 E-class P450 group I signature 380 390 8.0E-31 T 29-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS38450 9ac47ec4bc530de18cf6fd3d2cfa41f5 464 PRINTS PR00463 E-class P450 group I signature 390 413 8.0E-31 T 29-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS38450 9ac47ec4bc530de18cf6fd3d2cfa41f5 464 PRINTS PR00385 P450 superfamily signature 390 401 8.7E-15 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS38450 9ac47ec4bc530de18cf6fd3d2cfa41f5 464 PRINTS PR00385 P450 superfamily signature 266 283 8.7E-15 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS38450 9ac47ec4bc530de18cf6fd3d2cfa41f5 464 PRINTS PR00385 P450 superfamily signature 307 318 8.7E-15 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS38450 9ac47ec4bc530de18cf6fd3d2cfa41f5 464 PRINTS PR00385 P450 superfamily signature 381 390 8.7E-15 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS38450 9ac47ec4bc530de18cf6fd3d2cfa41f5 464 Pfam PF00067 Cytochrome P450 19 425 4.8E-69 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS38450 9ac47ec4bc530de18cf6fd3d2cfa41f5 464 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 383 392 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMALA_RS38450 9ac47ec4bc530de18cf6fd3d2cfa41f5 464 SUPERFAMILY SSF48264 19 160 5.24E-95 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS38450 9ac47ec4bc530de18cf6fd3d2cfa41f5 464 SUPERFAMILY SSF48264 188 434 5.24E-95 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS38450 9ac47ec4bc530de18cf6fd3d2cfa41f5 464 Gene3D G3DSA:1.10.630.10 8 439 2.4E-100 T 29-03-2018 SMALA_RS36895 4017cc5b85e9e1d1702d44c566122b8a 333 Gene3D G3DSA:3.30.465.10 56 127 4.4E-13 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SMALA_RS36895 4017cc5b85e9e1d1702d44c566122b8a 333 Gene3D G3DSA:3.30.465.10 139 221 9.4E-16 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SMALA_RS36895 4017cc5b85e9e1d1702d44c566122b8a 333 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 229 320 2.4E-17 T 29-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal SMALA_RS36895 4017cc5b85e9e1d1702d44c566122b8a 333 Gene3D G3DSA:3.30.43.10 1 51 1.4E-16 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 SMALA_RS36895 4017cc5b85e9e1d1702d44c566122b8a 333 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 3 220 2.0E-46 T 29-03-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 SMALA_RS36895 4017cc5b85e9e1d1702d44c566122b8a 333 Gene3D G3DSA:3.30.390.50 223 333 2.2E-23 T 29-03-2018 SMALA_RS36895 4017cc5b85e9e1d1702d44c566122b8a 333 SUPERFAMILY SSF55447 226 324 1.28E-24 T 29-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal SMALA_RS36895 4017cc5b85e9e1d1702d44c566122b8a 333 SMART SM01092 227 326 1.2E-22 T 29-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal SMALA_RS36895 4017cc5b85e9e1d1702d44c566122b8a 333 SUPERFAMILY SSF56176 1 220 1.5E-57 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SMALA_RS19845 8bca375298ff5b72cb035ac4c7923a08 670 SUPERFAMILY SSF54184 381 443 8.24E-5 T 29-03-2018 SMALA_RS19845 8bca375298ff5b72cb035ac4c7923a08 670 SMART SM00220 11 277 2.1E-68 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMALA_RS19845 8bca375298ff5b72cb035ac4c7923a08 670 SUPERFAMILY SSF54184 452 511 3.53E-5 T 29-03-2018 SMALA_RS19845 8bca375298ff5b72cb035ac4c7923a08 670 SUPERFAMILY SSF54184 517 578 4.71E-6 T 29-03-2018 SMALA_RS19845 8bca375298ff5b72cb035ac4c7923a08 670 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 134 146 - T 29-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMALA_RS19845 8bca375298ff5b72cb035ac4c7923a08 670 Gene3D G3DSA:3.30.200.20 1 99 5.9E-24 T 29-03-2018 SMALA_RS19845 8bca375298ff5b72cb035ac4c7923a08 670 Gene3D G3DSA:1.10.510.10 100 494 2.1E-51 T 29-03-2018 SMALA_RS19845 8bca375298ff5b72cb035ac4c7923a08 670 Pfam PF00069 Protein kinase domain 11 264 5.0E-50 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMALA_RS19845 8bca375298ff5b72cb035ac4c7923a08 670 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 17 40 - T 29-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 SMALA_RS19845 8bca375298ff5b72cb035ac4c7923a08 670 SMART SM00740 377 444 3.8E-14 T 29-03-2018 IPR005543 PASTA domain SMALA_RS19845 8bca375298ff5b72cb035ac4c7923a08 670 SMART SM00740 514 580 2.9E-16 T 29-03-2018 IPR005543 PASTA domain SMALA_RS19845 8bca375298ff5b72cb035ac4c7923a08 670 SMART SM00740 448 513 1.8E-14 T 29-03-2018 IPR005543 PASTA domain SMALA_RS19845 8bca375298ff5b72cb035ac4c7923a08 670 SMART SM00740 584 648 8.6E-7 T 29-03-2018 IPR005543 PASTA domain SMALA_RS19845 8bca375298ff5b72cb035ac4c7923a08 670 Pfam PF03793 PASTA domain 452 512 1.9E-15 T 29-03-2018 IPR005543 PASTA domain SMALA_RS19845 8bca375298ff5b72cb035ac4c7923a08 670 Pfam PF03793 PASTA domain 518 580 8.9E-15 T 29-03-2018 IPR005543 PASTA domain SMALA_RS19845 8bca375298ff5b72cb035ac4c7923a08 670 Pfam PF03793 PASTA domain 381 444 7.7E-12 T 29-03-2018 IPR005543 PASTA domain SMALA_RS19845 8bca375298ff5b72cb035ac4c7923a08 670 Pfam PF03793 PASTA domain 588 646 3.0E-10 T 29-03-2018 IPR005543 PASTA domain SMALA_RS19845 8bca375298ff5b72cb035ac4c7923a08 670 SUPERFAMILY SSF56112 7 273 4.72E-78 T 29-03-2018 IPR011009 Protein kinase-like domain SMALA_RS06550 32373451c113d9dd14c9af78f8ed1dcc 230 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 50 66 7.6E-8 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS06550 32373451c113d9dd14c9af78f8ed1dcc 230 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 36 50 7.6E-8 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS06550 32373451c113d9dd14c9af78f8ed1dcc 230 SUPERFAMILY SSF48008 96 219 1.15E-22 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS06550 32373451c113d9dd14c9af78f8ed1dcc 230 Pfam PF07729 FCD domain 97 219 7.9E-22 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS06550 32373451c113d9dd14c9af78f8ed1dcc 230 SUPERFAMILY SSF46785 11 80 2.61E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS06550 32373451c113d9dd14c9af78f8ed1dcc 230 SMART SM00895 97 221 5.2E-20 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS06550 32373451c113d9dd14c9af78f8ed1dcc 230 SMART SM00345 17 76 7.1E-20 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS06550 32373451c113d9dd14c9af78f8ed1dcc 230 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 76 2.0E-19 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS06550 32373451c113d9dd14c9af78f8ed1dcc 230 Gene3D G3DSA:1.10.10.10 1 77 6.3E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS06550 32373451c113d9dd14c9af78f8ed1dcc 230 Gene3D G3DSA:1.20.120.530 78 230 2.8E-23 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS29665 8a14246643a657545dd2e464ab60fea8 381 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 82 107 - T 29-03-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 SMALA_RS29665 8a14246643a657545dd2e464ab60fea8 381 SUPERFAMILY SSF54826 1 112 1.84E-30 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMALA_RS29665 8a14246643a657545dd2e464ab60fea8 381 Pfam PF13378 Enolase C-terminal domain-like 128 354 3.3E-57 T 29-03-2018 IPR029065 Enolase C-terminal domain-like SMALA_RS29665 8a14246643a657545dd2e464ab60fea8 381 Gene3D G3DSA:3.30.390.10 1 108 1.9E-35 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMALA_RS29665 8a14246643a657545dd2e464ab60fea8 381 SUPERFAMILY SSF51604 95 358 3.68E-68 T 29-03-2018 IPR029065 Enolase C-terminal domain-like SMALA_RS29665 8a14246643a657545dd2e464ab60fea8 381 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 180 211 - T 29-03-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 SMALA_RS29665 8a14246643a657545dd2e464ab60fea8 381 Gene3D G3DSA:3.20.20.120 109 373 3.0E-61 T 29-03-2018 IPR029065 Enolase C-terminal domain-like SMALA_RS29665 8a14246643a657545dd2e464ab60fea8 381 SMART SM00922 125 230 8.6E-19 T 29-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal SMALA_RS29665 8a14246643a657545dd2e464ab60fea8 381 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 16 107 1.8E-22 T 29-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain SMALA_RS18400 ef6becd52e913889e77cc7dc7e5884fa 425 Pfam PF00330 Aconitase family (aconitate hydratase) 83 415 4.0E-88 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS18400 ef6becd52e913889e77cc7dc7e5884fa 425 Gene3D G3DSA:3.30.499.10 27 150 5.7E-30 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS18400 ef6becd52e913889e77cc7dc7e5884fa 425 PRINTS PR00415 Aconitase family signature 301 312 5.5E-19 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS18400 ef6becd52e913889e77cc7dc7e5884fa 425 PRINTS PR00415 Aconitase family signature 357 370 5.5E-19 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS18400 ef6becd52e913889e77cc7dc7e5884fa 425 PRINTS PR00415 Aconitase family signature 206 219 5.5E-19 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS18400 ef6becd52e913889e77cc7dc7e5884fa 425 PRINTS PR00415 Aconitase family signature 116 129 5.5E-19 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS18400 ef6becd52e913889e77cc7dc7e5884fa 425 PRINTS PR00415 Aconitase family signature 130 145 5.5E-19 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS18400 ef6becd52e913889e77cc7dc7e5884fa 425 PRINTS PR00415 Aconitase family signature 192 205 5.5E-19 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS18400 ef6becd52e913889e77cc7dc7e5884fa 425 Gene3D G3DSA:3.30.499.10 278 425 4.0E-51 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS18400 ef6becd52e913889e77cc7dc7e5884fa 425 TIGRFAM TIGR02086 IPMI_arch: 3-isopropylmalate dehydratase, large subunit 8 421 2.3E-140 T 29-03-2018 IPR011826 Homoaconitase/3-isopropylmalate dehydratase, large subunit, prokaryotic GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 SMALA_RS18400 ef6becd52e913889e77cc7dc7e5884fa 425 SUPERFAMILY SSF53732 9 423 5.49E-121 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS18400 ef6becd52e913889e77cc7dc7e5884fa 425 Gene3D G3DSA:3.40.1060.10 151 277 7.2E-35 T 29-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS18400 ef6becd52e913889e77cc7dc7e5884fa 425 TIGRFAM TIGR01343 hacA_fam: homoaconitate hydratase family protein 8 420 1.1E-141 T 29-03-2018 IPR006251 Homoaconitase/3-isopropylmalate dehydratase, large subunit GO:0008652|GO:0016836|GO:0051539 KEGG: 00290+4.2.1.33 SMALA_RS17905 cf5a51cd1bc4ff8e25a08f285ad99843 328 SMART SM00829 14 325 2.9E-10 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS17905 cf5a51cd1bc4ff8e25a08f285ad99843 328 Pfam PF00107 Zinc-binding dehydrogenase 161 265 3.6E-17 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMALA_RS17905 cf5a51cd1bc4ff8e25a08f285ad99843 328 SUPERFAMILY SSF50129 1 155 1.31E-29 T 29-03-2018 IPR011032 GroES-like SMALA_RS17905 cf5a51cd1bc4ff8e25a08f285ad99843 328 SUPERFAMILY SSF51735 123 275 2.63E-29 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS17905 cf5a51cd1bc4ff8e25a08f285ad99843 328 Gene3D G3DSA:3.90.180.10 1 328 2.7E-58 T 29-03-2018 SMALA_RS30485 227779d3cfbf17ef3d03264ce77fe8ed 318 SUPERFAMILY SSF46894 248 317 3.74E-17 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS30485 227779d3cfbf17ef3d03264ce77fe8ed 318 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 287 299 1.0E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS30485 227779d3cfbf17ef3d03264ce77fe8ed 318 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 271 287 1.0E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS30485 227779d3cfbf17ef3d03264ce77fe8ed 318 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 257 271 1.0E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS30485 227779d3cfbf17ef3d03264ce77fe8ed 318 Pfam PF13185 GAF domain 16 149 7.4E-9 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS30485 227779d3cfbf17ef3d03264ce77fe8ed 318 Gene3D G3DSA:1.10.10.10 246 318 1.2E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS30485 227779d3cfbf17ef3d03264ce77fe8ed 318 Gene3D G3DSA:3.30.450.40 15 191 3.5E-16 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS30485 227779d3cfbf17ef3d03264ce77fe8ed 318 SMART SM00421 254 311 6.2E-18 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS30485 227779d3cfbf17ef3d03264ce77fe8ed 318 Pfam PF00196 Bacterial regulatory proteins, luxR family 257 310 7.4E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS30485 227779d3cfbf17ef3d03264ce77fe8ed 318 SUPERFAMILY SSF55781 17 155 4.58E-13 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS25120 3e0e330c217687e652139f752045054b 497 Pfam PF07690 Major Facilitator Superfamily 293 481 2.3E-8 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS25120 3e0e330c217687e652139f752045054b 497 Pfam PF07690 Major Facilitator Superfamily 28 255 3.9E-14 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS25120 3e0e330c217687e652139f752045054b 497 Gene3D G3DSA:1.20.1250.20 266 493 6.8E-22 T 29-03-2018 SMALA_RS25120 3e0e330c217687e652139f752045054b 497 SUPERFAMILY SSF103473 22 215 4.45E-42 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS25120 3e0e330c217687e652139f752045054b 497 SUPERFAMILY SSF103473 263 479 4.45E-42 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS25120 3e0e330c217687e652139f752045054b 497 Gene3D G3DSA:1.20.1250.20 16 214 8.8E-17 T 29-03-2018 SMALA_RS13370 91d08e264924ceaac1cbe1e1986965b8 856 Gene3D G3DSA:2.60.40.1730 4 196 8.1E-33 T 29-03-2018 SMALA_RS13370 91d08e264924ceaac1cbe1e1986965b8 856 TIGRFAM TIGR02412 pepN_strep_liv: aminopeptidase N 5 850 0.0 T 29-03-2018 IPR012778 Peptidase M1, aminopeptidase GO:0004177|GO:0006508 KEGG: 00480+3.4.11.2|MetaCyc: PWY-4061|MetaCyc: PWY-6842|MetaCyc: PWY-7112 SMALA_RS13370 91d08e264924ceaac1cbe1e1986965b8 856 Pfam PF11838 ERAP1-like C-terminal domain 535 844 4.3E-60 T 29-03-2018 IPR024571 ERAP1-like C-terminal domain SMALA_RS13370 91d08e264924ceaac1cbe1e1986965b8 856 SUPERFAMILY SSF55486 206 456 1.9E-75 T 29-03-2018 SMALA_RS13370 91d08e264924ceaac1cbe1e1986965b8 856 SUPERFAMILY SSF63737 5 195 1.29E-36 T 29-03-2018 SMALA_RS13370 91d08e264924ceaac1cbe1e1986965b8 856 Gene3D G3DSA:1.10.390.10 281 449 6.5E-46 T 29-03-2018 SMALA_RS13370 91d08e264924ceaac1cbe1e1986965b8 856 Pfam PF01433 Peptidase family M1 domain 209 445 6.2E-63 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMALA_RS13370 91d08e264924ceaac1cbe1e1986965b8 856 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 135 150 2.6E-21 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMALA_RS13370 91d08e264924ceaac1cbe1e1986965b8 856 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 261 271 2.6E-21 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMALA_RS13370 91d08e264924ceaac1cbe1e1986965b8 856 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 295 310 2.6E-21 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMALA_RS13370 91d08e264924ceaac1cbe1e1986965b8 856 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 314 326 2.6E-21 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMALA_RS13370 91d08e264924ceaac1cbe1e1986965b8 856 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 178 193 2.6E-21 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMALA_RS26110 bba68213c07712d82176ec3cc02a805f 957 Gene3D G3DSA:1.25.40.10 674 955 9.4E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS26110 bba68213c07712d82176ec3cc02a805f 957 Hamap MF_01600 UPF0182 protein . 1 868 18.008 T 29-03-2018 IPR005372 Uncharacterised protein family UPF0182 GO:0016021 SMALA_RS26110 bba68213c07712d82176ec3cc02a805f 957 Pfam PF03699 Uncharacterised protein family (UPF0182) 2 788 1.5E-275 T 29-03-2018 IPR005372 Uncharacterised protein family UPF0182 GO:0016021 SMALA_RS27710 96580380b5140098d4d5650bc535ce21 971 SMART SM00267 465 645 1.9E-58 T 29-03-2018 IPR000160 GGDEF domain SMALA_RS27710 96580380b5140098d4d5650bc535ce21 971 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 472 644 1.7E-40 T 29-03-2018 IPR000160 GGDEF domain SMALA_RS27710 96580380b5140098d4d5650bc535ce21 971 SUPERFAMILY SSF55785 342 463 2.93E-16 T 29-03-2018 IPR000014 PAS domain SMALA_RS27710 96580380b5140098d4d5650bc535ce21 971 Gene3D G3DSA:3.30.70.270 479 653 7.7E-61 T 29-03-2018 SMALA_RS27710 96580380b5140098d4d5650bc535ce21 971 Gene3D G3DSA:3.30.450.20 327 478 7.6E-25 T 29-03-2018 SMALA_RS27710 96580380b5140098d4d5650bc535ce21 971 SMART SM00052 655 908 4.3E-51 T 29-03-2018 IPR001633 EAL domain SMALA_RS27710 96580380b5140098d4d5650bc535ce21 971 Gene3D G3DSA:3.20.20.450 654 917 1.3E-78 T 29-03-2018 IPR001633 EAL domain SMALA_RS27710 96580380b5140098d4d5650bc535ce21 971 Pfam PF00563 EAL domain 662 903 1.6E-49 T 29-03-2018 IPR001633 EAL domain SMALA_RS27710 96580380b5140098d4d5650bc535ce21 971 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 350 472 5.5E-15 T 29-03-2018 IPR000014 PAS domain SMALA_RS27710 96580380b5140098d4d5650bc535ce21 971 Pfam PF08448 PAS fold 360 467 1.2E-7 T 29-03-2018 IPR013656 PAS fold-4 SMALA_RS27710 96580380b5140098d4d5650bc535ce21 971 SUPERFAMILY SSF141868 662 914 1.06E-54 T 29-03-2018 IPR001633 EAL domain SMALA_RS27710 96580380b5140098d4d5650bc535ce21 971 SUPERFAMILY SSF55073 481 646 1.41E-42 T 29-03-2018 IPR029787 Nucleotide cyclase SMALA_RS27710 96580380b5140098d4d5650bc535ce21 971 Pfam PF00990 Diguanylate cyclase, GGDEF domain 476 641 1.1E-40 T 29-03-2018 IPR000160 GGDEF domain SMALA_RS27710 96580380b5140098d4d5650bc535ce21 971 SMART SM00091 353 419 3.0E-9 T 29-03-2018 IPR000014 PAS domain SMALA_RS34295 1b558af44bdcb147f957b47cbcc4df98 230 SUPERFAMILY SSF52172 8 128 5.83E-33 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS34295 1b558af44bdcb147f957b47cbcc4df98 230 PIRSF PIRSF006171 6 230 2.0E-83 T 29-03-2018 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0001071|GO:0003677|GO:0005737|GO:0009605 SMALA_RS34295 1b558af44bdcb147f957b47cbcc4df98 230 Pfam PF00072 Response regulator receiver domain 10 121 7.3E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS34295 1b558af44bdcb147f957b47cbcc4df98 230 Gene3D G3DSA:3.40.50.2300 7 144 1.7E-30 T 29-03-2018 SMALA_RS34295 1b558af44bdcb147f957b47cbcc4df98 230 Gene3D G3DSA:1.10.10.10 162 228 1.4E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS34295 1b558af44bdcb147f957b47cbcc4df98 230 SMART SM00448 8 121 1.1E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS11860 85c6c2be171c7c6b8bf4fd26ce5835fc 322 Pfam PF13602 Zinc-binding dehydrogenase 214 317 3.8E-9 T 29-03-2018 SMALA_RS11860 85c6c2be171c7c6b8bf4fd26ce5835fc 322 SMART SM00829 22 317 6.8E-12 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS11860 85c6c2be171c7c6b8bf4fd26ce5835fc 322 SUPERFAMILY SSF50129 12 174 4.41E-28 T 29-03-2018 IPR011032 GroES-like SMALA_RS11860 85c6c2be171c7c6b8bf4fd26ce5835fc 322 Gene3D G3DSA:3.90.180.10 1 168 5.5E-41 T 29-03-2018 SMALA_RS11860 85c6c2be171c7c6b8bf4fd26ce5835fc 322 Gene3D G3DSA:3.90.180.10 169 319 3.5E-12 T 29-03-2018 SMALA_RS11860 85c6c2be171c7c6b8bf4fd26ce5835fc 322 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 161 182 - T 29-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 SMALA_RS11860 85c6c2be171c7c6b8bf4fd26ce5835fc 322 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 40 102 1.9E-7 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS11860 85c6c2be171c7c6b8bf4fd26ce5835fc 322 SUPERFAMILY SSF51735 134 261 4.96E-22 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS06215 960df7824a87a1e152a6274e5aa06c91 72 SUPERFAMILY SSF47473 5 70 2.09E-17 T 29-03-2018 IPR011992 EF-hand domain pair SMALA_RS06215 960df7824a87a1e152a6274e5aa06c91 72 Gene3D G3DSA:1.10.238.10 29 72 2.5E-13 T 29-03-2018 SMALA_RS06215 960df7824a87a1e152a6274e5aa06c91 72 SMART SM00054 45 72 9.2 T 29-03-2018 IPR002048 EF-hand domain GO:0005509 SMALA_RS06215 960df7824a87a1e152a6274e5aa06c91 72 SMART SM00054 8 36 0.0033 T 29-03-2018 IPR002048 EF-hand domain GO:0005509 SMALA_RS06215 960df7824a87a1e152a6274e5aa06c91 72 ProSitePatterns PS00018 EF-hand calcium-binding domain. 54 66 - T 29-03-2018 IPR018247 EF-Hand 1, calcium-binding site SMALA_RS06215 960df7824a87a1e152a6274e5aa06c91 72 Gene3D G3DSA:1.10.238.10 1 28 2.7E-6 T 29-03-2018 SMALA_RS06215 960df7824a87a1e152a6274e5aa06c91 72 ProSitePatterns PS00018 EF-hand calcium-binding domain. 17 29 - T 29-03-2018 IPR018247 EF-Hand 1, calcium-binding site SMALA_RS06215 960df7824a87a1e152a6274e5aa06c91 72 Pfam PF13499 EF-hand domain pair 8 70 1.0E-13 T 29-03-2018 IPR002048 EF-hand domain GO:0005509 SMALA_RS06925 5cac8f51151db6cac4a855a7208c8ae4 600 ProSitePatterns PS00888 Cyclic nucleotide-binding domain signature 1. 53 69 - T 29-03-2018 IPR018488 Cyclic nucleotide-binding, conserved site SMALA_RS06925 5cac8f51151db6cac4a855a7208c8ae4 600 Gene3D G3DSA:3.50.50.60 367 476 1.2E-18 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS06925 5cac8f51151db6cac4a855a7208c8ae4 600 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 474 490 6.4E-26 T 29-03-2018 SMALA_RS06925 5cac8f51151db6cac4a855a7208c8ae4 600 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 519 541 6.4E-26 T 29-03-2018 SMALA_RS06925 5cac8f51151db6cac4a855a7208c8ae4 600 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 244 263 6.4E-26 T 29-03-2018 SMALA_RS06925 5cac8f51151db6cac4a855a7208c8ae4 600 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 344 362 6.4E-26 T 29-03-2018 SMALA_RS06925 5cac8f51151db6cac4a855a7208c8ae4 600 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 387 405 6.4E-26 T 29-03-2018 SMALA_RS06925 5cac8f51151db6cac4a855a7208c8ae4 600 SUPERFAMILY SSF51206 29 149 9.03E-23 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like SMALA_RS06925 5cac8f51151db6cac4a855a7208c8ae4 600 SUPERFAMILY SSF51905 227 566 2.32E-39 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS06925 5cac8f51151db6cac4a855a7208c8ae4 600 Gene3D G3DSA:3.50.50.60 233 366 3.3E-18 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS06925 5cac8f51151db6cac4a855a7208c8ae4 600 SMART SM00100 26 144 1.8E-15 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain SMALA_RS06925 5cac8f51151db6cac4a855a7208c8ae4 600 Gene3D G3DSA:2.60.120.10 28 148 4.0E-19 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SMALA_RS06925 5cac8f51151db6cac4a855a7208c8ae4 600 Gene3D G3DSA:3.50.50.60 477 584 3.5E-8 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS06925 5cac8f51151db6cac4a855a7208c8ae4 600 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 276 291 1.5E-32 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMALA_RS06925 5cac8f51151db6cac4a855a7208c8ae4 600 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 243 265 1.5E-32 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMALA_RS06925 5cac8f51151db6cac4a855a7208c8ae4 600 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 529 547 1.5E-32 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMALA_RS06925 5cac8f51151db6cac4a855a7208c8ae4 600 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 345 353 1.5E-32 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMALA_RS06925 5cac8f51151db6cac4a855a7208c8ae4 600 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 383 407 1.5E-32 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMALA_RS06925 5cac8f51151db6cac4a855a7208c8ae4 600 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 243 555 4.0E-26 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS06925 5cac8f51151db6cac4a855a7208c8ae4 600 Pfam PF00027 Cyclic nucleotide-binding domain 46 131 2.4E-16 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain SMALA_RS20090 26be49fa19ee34d03675a34d60cdff6e 655 SUPERFAMILY SSF48452 101 266 7.59E-32 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS20090 26be49fa19ee34d03675a34d60cdff6e 655 SMART SM01043 105 247 3.7E-42 T 29-03-2018 IPR005158 Bacterial transcriptional activator domain SMALA_RS20090 26be49fa19ee34d03675a34d60cdff6e 655 Gene3D G3DSA:3.40.50.300 296 457 2.6E-11 T 29-03-2018 SMALA_RS20090 26be49fa19ee34d03675a34d60cdff6e 655 Pfam PF03704 Bacterial transcriptional activator domain 105 247 6.3E-38 T 29-03-2018 IPR005158 Bacterial transcriptional activator domain SMALA_RS20090 26be49fa19ee34d03675a34d60cdff6e 655 Pfam PF00931 NB-ARC domain 338 526 4.6E-10 T 29-03-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207 SMALA_RS20090 26be49fa19ee34d03675a34d60cdff6e 655 Pfam PF00486 Transcriptional regulatory protein, C terminal 27 84 7.4E-9 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS20090 26be49fa19ee34d03675a34d60cdff6e 655 PRINTS PR00364 Disease resistance protein signature 340 355 5.1E-7 T 29-03-2018 SMALA_RS20090 26be49fa19ee34d03675a34d60cdff6e 655 PRINTS PR00364 Disease resistance protein signature 418 432 5.1E-7 T 29-03-2018 SMALA_RS20090 26be49fa19ee34d03675a34d60cdff6e 655 PRINTS PR00364 Disease resistance protein signature 506 520 5.1E-7 T 29-03-2018 SMALA_RS20090 26be49fa19ee34d03675a34d60cdff6e 655 SMART SM00862 17 98 2.1E-9 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS20090 26be49fa19ee34d03675a34d60cdff6e 655 SUPERFAMILY SSF52540 296 566 7.5E-20 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS20090 26be49fa19ee34d03675a34d60cdff6e 655 SUPERFAMILY SSF46894 4 85 3.68E-11 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS20090 26be49fa19ee34d03675a34d60cdff6e 655 Gene3D G3DSA:1.10.10.10 1 101 3.2E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS20090 26be49fa19ee34d03675a34d60cdff6e 655 Gene3D G3DSA:1.10.10.10 542 638 5.0E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS20090 26be49fa19ee34d03675a34d60cdff6e 655 Gene3D G3DSA:1.25.40.10 102 280 2.3E-23 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS28115 e18285f60e28e7594276570274a31bc7 516 SMART SM00963 1 86 1.9E-33 T 29-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 SMALA_RS28115 e18285f60e28e7594276570274a31bc7 516 Pfam PF02881 SRP54-type protein, helical bundle domain 5 82 3.6E-21 T 29-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 SMALA_RS28115 e18285f60e28e7594276570274a31bc7 516 SUPERFAMILY SSF47446 331 432 8.01E-34 T 29-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 SMALA_RS28115 e18285f60e28e7594276570274a31bc7 516 Pfam PF02978 Signal peptide binding domain 331 429 2.4E-31 T 29-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 SMALA_RS28115 e18285f60e28e7594276570274a31bc7 516 SMART SM00382 99 303 1.6E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS28115 e18285f60e28e7594276570274a31bc7 516 SMART SM00962 100 298 9.8E-105 T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 SMALA_RS28115 e18285f60e28e7594276570274a31bc7 516 Pfam PF00448 SRP54-type protein, GTPase domain 100 298 2.7E-68 T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 SMALA_RS28115 e18285f60e28e7594276570274a31bc7 516 SUPERFAMILY SSF52540 42 358 5.31E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS28115 e18285f60e28e7594276570274a31bc7 516 TIGRFAM TIGR00959 ffh: signal recognition particle protein 2 431 8.0E-173 T 29-03-2018 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 SMALA_RS28115 e18285f60e28e7594276570274a31bc7 516 Gene3D G3DSA:1.10.260.30 331 434 2.2E-36 T 29-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 SMALA_RS28115 e18285f60e28e7594276570274a31bc7 516 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 5 450 33.329 T 29-03-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 SMALA_RS28115 e18285f60e28e7594276570274a31bc7 516 Gene3D G3DSA:1.20.120.140 1 91 7.2E-29 T 29-03-2018 SMALA_RS28115 e18285f60e28e7594276570274a31bc7 516 Gene3D G3DSA:3.40.50.300 92 299 1.1E-39 T 29-03-2018 SMALA_RS41905 01f3859e7c8d7f21a4fae6536b386c17 573 Gene3D G3DSA:3.40.190.10 246 339 7.0E-25 T 29-03-2018 SMALA_RS41905 01f3859e7c8d7f21a4fae6536b386c17 573 SUPERFAMILY SSF53850 94 561 2.53E-107 T 29-03-2018 SMALA_RS41905 01f3859e7c8d7f21a4fae6536b386c17 573 Gene3D G3DSA:3.10.105.10 340 538 2.2E-33 T 29-03-2018 SMALA_RS41905 01f3859e7c8d7f21a4fae6536b386c17 573 Gene3D G3DSA:3.90.76.10 109 245 2.0E-30 T 29-03-2018 SMALA_RS41905 01f3859e7c8d7f21a4fae6536b386c17 573 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 144 485 5.7E-77 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain SMALA_RS41905 01f3859e7c8d7f21a4fae6536b386c17 573 PIRSF PIRSF002741 56 563 7.1E-74 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 SMALA_RS04420 5bdb8617227253da0c05fc6d274219e2 981 SUPERFAMILY SSF52540 42 264 9.6E-11 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS04420 5bdb8617227253da0c05fc6d274219e2 981 Gene3D G3DSA:1.25.40.10 753 870 7.1E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS04420 5bdb8617227253da0c05fc6d274219e2 981 SMART SM00421 912 969 4.0E-15 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS04420 5bdb8617227253da0c05fc6d274219e2 981 Pfam PF13191 AAA ATPase domain 37 183 6.8E-15 T 29-03-2018 SMALA_RS04420 5bdb8617227253da0c05fc6d274219e2 981 Gene3D G3DSA:1.10.10.10 904 972 3.2E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS04420 5bdb8617227253da0c05fc6d274219e2 981 Gene3D G3DSA:1.25.40.10 386 736 5.3E-13 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS04420 5bdb8617227253da0c05fc6d274219e2 981 SUPERFAMILY SSF46894 907 969 1.43E-14 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS04420 5bdb8617227253da0c05fc6d274219e2 981 Gene3D G3DSA:3.40.50.300 10 207 7.6E-7 T 29-03-2018 SMALA_RS04420 5bdb8617227253da0c05fc6d274219e2 981 Pfam PF00196 Bacterial regulatory proteins, luxR family 914 966 3.0E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS04420 5bdb8617227253da0c05fc6d274219e2 981 SUPERFAMILY SSF48452 600 701 3.42E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS10455 3f108989efd3aa49012c2d36bfef7bc4 146 Gene3D G3DSA:3.30.530.20 3 146 8.2E-25 T 29-03-2018 IPR023393 START-like domain SMALA_RS10455 3f108989efd3aa49012c2d36bfef7bc4 146 SUPERFAMILY SSF55961 1 145 4.98E-29 T 29-03-2018 SMALA_RS10455 3f108989efd3aa49012c2d36bfef7bc4 146 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 11 139 3.1E-13 T 29-03-2018 IPR005031 Coenzyme Q-binding protein COQ10, START domain Reactome: R-HSA-611105 SMALA_RS05915 a8647f24dedbe889dda11c481b774ad8 2062 Pfam PF08659 KR domain 1446 1666 2.3E-14 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS05915 a8647f24dedbe889dda11c481b774ad8 2062 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 1.5E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS05915 a8647f24dedbe889dda11c481b774ad8 2062 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 1.5E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS05915 a8647f24dedbe889dda11c481b774ad8 2062 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 1.5E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS05915 a8647f24dedbe889dda11c481b774ad8 2062 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 1.5E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS05915 a8647f24dedbe889dda11c481b774ad8 2062 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 1.5E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS05915 a8647f24dedbe889dda11c481b774ad8 2062 Gene3D G3DSA:3.40.50.720 1436 1719 1.3E-23 T 29-03-2018 SMALA_RS05915 a8647f24dedbe889dda11c481b774ad8 2062 Gene3D G3DSA:3.40.47.10 390 676 1.1E-46 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS05915 a8647f24dedbe889dda11c481b774ad8 2062 SUPERFAMILY SSF53901 631 835 2.63E-52 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS05915 a8647f24dedbe889dda11c481b774ad8 2062 Pfam PF14765 Polyketide synthase dehydratase 1779 2045 2.0E-10 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS05915 a8647f24dedbe889dda11c481b774ad8 2062 SUPERFAMILY SSF51735 1442 1486 5.62E-21 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS05915 a8647f24dedbe889dda11c481b774ad8 2062 SUPERFAMILY SSF51735 1525 1713 5.62E-21 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS05915 a8647f24dedbe889dda11c481b774ad8 2062 Gene3D G3DSA:3.40.47.10 848 1109 2.9E-20 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS05915 a8647f24dedbe889dda11c481b774ad8 2062 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 898 1061 4.2E-11 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS05915 a8647f24dedbe889dda11c481b774ad8 2062 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 389 662 2.2E-27 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS05915 a8647f24dedbe889dda11c481b774ad8 2062 SUPERFAMILY SSF51735 8 255 2.61E-64 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS05915 a8647f24dedbe889dda11c481b774ad8 2062 SMART SM00825 Beta-ketoacyl synthase 389 836 2.0E-29 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS05915 a8647f24dedbe889dda11c481b774ad8 2062 Gene3D G3DSA:3.10.129.10 1756 1893 2.0E-5 T 29-03-2018 SMALA_RS05915 a8647f24dedbe889dda11c481b774ad8 2062 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1444 1667 8.1E-8 T 29-03-2018 SMALA_RS05915 a8647f24dedbe889dda11c481b774ad8 2062 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 671 782 8.4E-25 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS05915 a8647f24dedbe889dda11c481b774ad8 2062 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 253 2.3E-49 T 29-03-2018 SMALA_RS05915 a8647f24dedbe889dda11c481b774ad8 2062 SUPERFAMILY SSF53901 389 670 1.02E-35 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS05915 a8647f24dedbe889dda11c481b774ad8 2062 Gene3D G3DSA:3.40.47.10 678 836 9.2E-40 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS05915 a8647f24dedbe889dda11c481b774ad8 2062 SUPERFAMILY SSF53901 891 962 6.22E-19 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS05915 a8647f24dedbe889dda11c481b774ad8 2062 SUPERFAMILY SSF53901 993 1105 6.22E-19 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS05915 a8647f24dedbe889dda11c481b774ad8 2062 Gene3D G3DSA:3.40.50.720 1 260 9.8E-57 T 29-03-2018 SMALA_RS22765 4214e8e360051b69fb143c26c03ae01d 615 SUPERFAMILY SSF56235 2 237 1.54E-66 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SMALA_RS22765 4214e8e360051b69fb143c26c03ae01d 615 Gene3D G3DSA:3.60.20.10 2 241 2.5E-67 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SMALA_RS22765 4214e8e360051b69fb143c26c03ae01d 615 Gene3D G3DSA:3.40.50.10490 461 613 3.4E-46 T 29-03-2018 SMALA_RS22765 4214e8e360051b69fb143c26c03ae01d 615 Pfam PF01380 SIS domain 292 418 1.1E-34 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 SMALA_RS22765 4214e8e360051b69fb143c26c03ae01d 615 Pfam PF01380 SIS domain 464 596 9.9E-24 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 SMALA_RS22765 4214e8e360051b69fb143c26c03ae01d 615 Gene3D G3DSA:3.40.50.10490 242 460 6.9E-68 T 29-03-2018 SMALA_RS22765 4214e8e360051b69fb143c26c03ae01d 615 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 615 41.113 T 29-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 SMALA_RS22765 4214e8e360051b69fb143c26c03ae01d 615 Pfam PF13522 Glutamine amidotransferase domain 65 195 6.5E-23 T 29-03-2018 SMALA_RS22765 4214e8e360051b69fb143c26c03ae01d 615 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 615 7.5E-248 T 29-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 SMALA_RS22765 4214e8e360051b69fb143c26c03ae01d 615 SUPERFAMILY SSF53697 247 615 8.26E-111 T 29-03-2018 SMALA_RS18430 020ad2e85d4281e31443453e8577c6a0 429 SUPERFAMILY SSF51905 273 294 6.17E-25 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS18430 020ad2e85d4281e31443453e8577c6a0 429 SUPERFAMILY SSF51905 233 243 6.17E-25 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS18430 020ad2e85d4281e31443453e8577c6a0 429 SUPERFAMILY SSF51905 11 188 6.17E-25 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS18430 020ad2e85d4281e31443453e8577c6a0 429 SUPERFAMILY SSF51905 344 403 6.17E-25 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS18430 020ad2e85d4281e31443453e8577c6a0 429 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 27 49 5.1E-6 T 29-03-2018 SMALA_RS18430 020ad2e85d4281e31443453e8577c6a0 429 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 170 179 5.1E-6 T 29-03-2018 SMALA_RS18430 020ad2e85d4281e31443453e8577c6a0 429 Gene3D G3DSA:3.50.50.60 14 408 3.5E-24 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS18430 020ad2e85d4281e31443453e8577c6a0 429 Pfam PF12831 FAD dependent oxidoreductase 27 422 2.6E-64 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS02630 cf43fd3a52feb644339104f50709accc 1590 Gene3D G3DSA:3.40.50.980 480 672 6.1E-46 T 29-03-2018 SMALA_RS02630 cf43fd3a52feb644339104f50709accc 1590 SMART SM00823 Phosphopantetheine attachment site 1042 1111 5.5E-7 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS02630 cf43fd3a52feb644339104f50709accc 1590 SUPERFAMILY SSF47336 1034 1107 3.01E-18 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS02630 cf43fd3a52feb644339104f50709accc 1590 SUPERFAMILY SSF52777 1312 1581 4.34E-41 T 29-03-2018 SMALA_RS02630 cf43fd3a52feb644339104f50709accc 1590 Gene3D G3DSA:2.30.38.10 837 918 2.3E-27 T 29-03-2018 SMALA_RS02630 cf43fd3a52feb644339104f50709accc 1590 Pfam PF13193 AMP-binding enzyme C-terminal domain 936 1015 6.4E-12 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS02630 cf43fd3a52feb644339104f50709accc 1590 Gene3D G3DSA:3.30.559.10 7 226 2.7E-47 T 29-03-2018 SMALA_RS02630 cf43fd3a52feb644339104f50709accc 1590 Pfam PF00668 Condensation domain 25 467 5.1E-100 T 29-03-2018 IPR001242 Condensation domain SMALA_RS02630 cf43fd3a52feb644339104f50709accc 1590 Pfam PF00668 Condensation domain 1130 1456 6.2E-75 T 29-03-2018 IPR001242 Condensation domain SMALA_RS02630 cf43fd3a52feb644339104f50709accc 1590 Pfam PF00501 AMP-binding enzyme 488 928 1.0E-89 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS02630 cf43fd3a52feb644339104f50709accc 1590 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 509 952 9.3E-128 T 29-03-2018 IPR010071 Amino acid adenylation domain SMALA_RS02630 cf43fd3a52feb644339104f50709accc 1590 Gene3D G3DSA:3.30.559.10 1111 1306 1.3E-41 T 29-03-2018 SMALA_RS02630 cf43fd3a52feb644339104f50709accc 1590 Pfam PF00550 Phosphopantetheine attachment site 1045 1106 3.1E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS02630 cf43fd3a52feb644339104f50709accc 1590 ProSitePatterns PS00455 Putative AMP-binding domain signature. 667 678 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS02630 cf43fd3a52feb644339104f50709accc 1590 SUPERFAMILY SSF56801 447 1054 2.88E-151 T 29-03-2018 SMALA_RS02630 cf43fd3a52feb644339104f50709accc 1590 SUPERFAMILY SSF52777 1133 1304 1.67E-46 T 29-03-2018 SMALA_RS02630 cf43fd3a52feb644339104f50709accc 1590 SUPERFAMILY SSF52777 211 452 8.67E-60 T 29-03-2018 SMALA_RS02630 cf43fd3a52feb644339104f50709accc 1590 Gene3D G3DSA:3.30.300.30 923 1047 7.0E-39 T 29-03-2018 SMALA_RS02630 cf43fd3a52feb644339104f50709accc 1590 Gene3D G3DSA:1.10.1200.10 1048 1110 8.6E-23 T 29-03-2018 SMALA_RS02630 cf43fd3a52feb644339104f50709accc 1590 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1066 1081 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS02630 cf43fd3a52feb644339104f50709accc 1590 Gene3D G3DSA:3.40.50.980 673 833 2.2E-25 T 29-03-2018 SMALA_RS02630 cf43fd3a52feb644339104f50709accc 1590 SUPERFAMILY SSF52777 28 204 2.89E-52 T 29-03-2018 SMALA_RS43050 23c91e1b186b5887ea70a81caebe6a72 385 Pfam PF03457 Helicase associated domain 260 320 1.0E-14 T 29-03-2018 IPR005114 Helicase-associated SMALA_RS43050 23c91e1b186b5887ea70a81caebe6a72 385 Pfam PF03457 Helicase associated domain 116 157 6.6E-7 T 29-03-2018 IPR005114 Helicase-associated SMALA_RS32095 b762943c0bb35c2386b7f38c719a5282 316 Gene3D G3DSA:1.10.600.10 3 312 8.9E-81 T 29-03-2018 IPR008949 Isoprenoid synthase domain SMALA_RS32095 b762943c0bb35c2386b7f38c719a5282 316 ProSitePatterns PS01044 Squalene and phytoene synthases signature 1. 137 152 - T 29-03-2018 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 SMALA_RS32095 b762943c0bb35c2386b7f38c719a5282 316 ProSitePatterns PS01045 Squalene and phytoene synthases signature 2. 176 201 - T 29-03-2018 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 SMALA_RS32095 b762943c0bb35c2386b7f38c719a5282 316 TIGRFAM TIGR03465 HpnD: squalene synthase HpnD 22 299 5.0E-93 T 29-03-2018 IPR017828 Squalene/phytoene synthase HpnD GO:0016117|GO:0016767 SMALA_RS32095 b762943c0bb35c2386b7f38c719a5282 316 Pfam PF00494 Squalene/phytoene synthase 24 287 1.3E-70 T 29-03-2018 IPR002060 Squalene/phytoene synthase GO:0009058|GO:0016740 SMALA_RS32095 b762943c0bb35c2386b7f38c719a5282 316 SUPERFAMILY SSF48576 14 302 2.09E-73 T 29-03-2018 IPR008949 Isoprenoid synthase domain SMALA_RS29915 723e62dab62413d44d7b6d4a4b289000 659 SUPERFAMILY SSF56601 237 257 3.75E-63 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMALA_RS29915 723e62dab62413d44d7b6d4a4b289000 659 SUPERFAMILY SSF56601 287 655 3.75E-63 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMALA_RS29915 723e62dab62413d44d7b6d4a4b289000 659 Gene3D G3DSA:3.40.710.10 274 658 1.5E-73 T 29-03-2018 SMALA_RS29915 723e62dab62413d44d7b6d4a4b289000 659 Pfam PF00905 Penicillin binding protein transpeptidase domain 432 609 1.6E-16 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 SMALA_RS29915 723e62dab62413d44d7b6d4a4b289000 659 Gene3D G3DSA:1.10.3810.10 70 270 1.3E-64 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 SMALA_RS29915 723e62dab62413d44d7b6d4a4b289000 659 Pfam PF00912 Transglycosylase 80 253 2.0E-55 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 SMALA_RS29915 723e62dab62413d44d7b6d4a4b289000 659 SUPERFAMILY SSF53955 66 273 1.77E-63 T 29-03-2018 IPR023346 Lysozyme-like domain SMALA_RS34970 78be19f4131e011b3ac92d6458b6dc50 331 Gene3D G3DSA:1.10.10.60 239 273 9.6E-14 T 29-03-2018 SMALA_RS34970 78be19f4131e011b3ac92d6458b6dc50 331 Pfam PF12833 Helix-turn-helix domain 244 322 1.1E-23 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS34970 78be19f4131e011b3ac92d6458b6dc50 331 SUPERFAMILY SSF52317 10 204 3.1E-39 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS34970 78be19f4131e011b3ac92d6458b6dc50 331 Gene3D G3DSA:1.10.10.60 274 330 1.9E-12 T 29-03-2018 SMALA_RS34970 78be19f4131e011b3ac92d6458b6dc50 331 Pfam PF01965 DJ-1/PfpI family 11 182 5.2E-14 T 29-03-2018 IPR002818 DJ-1/PfpI SMALA_RS34970 78be19f4131e011b3ac92d6458b6dc50 331 SMART SM00342 238 321 1.5E-27 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS34970 78be19f4131e011b3ac92d6458b6dc50 331 SUPERFAMILY SSF46689 274 325 5.82E-9 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS34970 78be19f4131e011b3ac92d6458b6dc50 331 SUPERFAMILY SSF46689 227 272 2.06E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS34970 78be19f4131e011b3ac92d6458b6dc50 331 Gene3D G3DSA:3.40.50.880 6 238 2.8E-54 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS27935 f03c456922f74dea10f6b1f09c16c3ec 191 Pfam PF00216 Bacterial DNA-binding protein 1 88 3.8E-24 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 SMALA_RS27935 f03c456922f74dea10f6b1f09c16c3ec 191 SMART SM00411 1 89 9.6E-39 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 SMALA_RS27935 f03c456922f74dea10f6b1f09c16c3ec 191 Gene3D G3DSA:4.10.520.10 1 96 1.2E-25 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 SMALA_RS27935 f03c456922f74dea10f6b1f09c16c3ec 191 SUPERFAMILY SSF47729 1 92 8.39E-25 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 SMALA_RS27935 f03c456922f74dea10f6b1f09c16c3ec 191 PRINTS PR01727 Prokaryotic integration host factor signature 39 54 8.8E-14 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 SMALA_RS27935 f03c456922f74dea10f6b1f09c16c3ec 191 PRINTS PR01727 Prokaryotic integration host factor signature 73 87 8.8E-14 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 SMALA_RS27935 f03c456922f74dea10f6b1f09c16c3ec 191 PRINTS PR01727 Prokaryotic integration host factor signature 57 70 8.8E-14 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 SMALA_RS27935 f03c456922f74dea10f6b1f09c16c3ec 191 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 45 64 - T 29-03-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 SMALA_RS19750 04707d043b38a0121ad3f13fcab3efb8 874 Gene3D G3DSA:3.30.1360.40 258 354 3.1E-31 T 29-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 SMALA_RS19750 04707d043b38a0121ad3f13fcab3efb8 874 SMART SM00434 29 486 4.5E-282 T 29-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMALA_RS19750 04707d043b38a0121ad3f13fcab3efb8 874 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 20 835 23.162 T 29-03-2018 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 SMALA_RS19750 04707d043b38a0121ad3f13fcab3efb8 874 SUPERFAMILY SSF101904 520 845 3.27E-97 T 29-03-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal SMALA_RS19750 04707d043b38a0121ad3f13fcab3efb8 874 Gene3D G3DSA:3.90.199.10 52 233 3.1E-82 T 29-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 SMALA_RS19750 04707d043b38a0121ad3f13fcab3efb8 874 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 50 493 2.3E-150 T 29-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMALA_RS19750 04707d043b38a0121ad3f13fcab3efb8 874 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 26 833 0.0 T 29-03-2018 SMALA_RS19750 04707d043b38a0121ad3f13fcab3efb8 874 Gene3D G3DSA:1.10.268.10 366 508 6.2E-50 T 29-03-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMALA_RS19750 04707d043b38a0121ad3f13fcab3efb8 874 Gene3D G3DSA:2.120.10.90 517 835 9.7E-117 T 29-03-2018 SMALA_RS19750 04707d043b38a0121ad3f13fcab3efb8 874 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 525 570 7.3E-14 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 SMALA_RS19750 04707d043b38a0121ad3f13fcab3efb8 874 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 632 665 8.7E-7 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 SMALA_RS19750 04707d043b38a0121ad3f13fcab3efb8 874 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 738 783 4.0E-12 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 SMALA_RS19750 04707d043b38a0121ad3f13fcab3efb8 874 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 684 732 2.8E-12 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 SMALA_RS19750 04707d043b38a0121ad3f13fcab3efb8 874 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 787 831 2.8E-11 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 SMALA_RS19750 04707d043b38a0121ad3f13fcab3efb8 874 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 576 622 1.5E-9 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 SMALA_RS19750 04707d043b38a0121ad3f13fcab3efb8 874 SUPERFAMILY SSF56719 48 508 2.35E-171 T 29-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 SMALA_RS09040 091061c82d9ebf93d51d7c221f23c018 510 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 431 441 - T 29-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site SMALA_RS09040 091061c82d9ebf93d51d7c221f23c018 510 PRINTS PR00723 Subtilisin serine protease family (S8) signature 430 446 1.8E-20 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related SMALA_RS09040 091061c82d9ebf93d51d7c221f23c018 510 PRINTS PR00723 Subtilisin serine protease family (S8) signature 173 192 1.8E-20 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related SMALA_RS09040 091061c82d9ebf93d51d7c221f23c018 510 PRINTS PR00723 Subtilisin serine protease family (S8) signature 221 234 1.8E-20 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related SMALA_RS09040 091061c82d9ebf93d51d7c221f23c018 510 SUPERFAMILY SSF52743 359 509 6.28E-78 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMALA_RS09040 091061c82d9ebf93d51d7c221f23c018 510 SUPERFAMILY SSF52743 153 332 6.28E-78 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMALA_RS09040 091061c82d9ebf93d51d7c221f23c018 510 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 225 235 - T 29-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site SMALA_RS09040 091061c82d9ebf93d51d7c221f23c018 510 Pfam PF00082 Subtilase family 174 477 1.9E-48 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMALA_RS09040 091061c82d9ebf93d51d7c221f23c018 510 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 178 189 - T 29-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site SMALA_RS09040 091061c82d9ebf93d51d7c221f23c018 510 Gene3D G3DSA:3.40.50.200 132 510 4.9E-78 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMALA_RS01720 791a6b83c1ea5a628132caa3c83112b7 568 Gene3D G3DSA:3.40.50.1820 42 347 2.9E-36 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS01720 791a6b83c1ea5a628132caa3c83112b7 568 SUPERFAMILY SSF49785 357 564 3.19E-47 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS01720 791a6b83c1ea5a628132caa3c83112b7 568 Gene3D G3DSA:2.60.120.260 348 562 1.7E-53 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS01720 791a6b83c1ea5a628132caa3c83112b7 568 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 344 555 2.0E-34 T 29-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 SMALA_RS01720 791a6b83c1ea5a628132caa3c83112b7 568 SUPERFAMILY SSF53474 36 363 6.88E-45 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS01720 791a6b83c1ea5a628132caa3c83112b7 568 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 53 556 4.2E-90 T 29-03-2018 IPR005674 CocE/Serine esterase GO:0016787 SMALA_RS01720 791a6b83c1ea5a628132caa3c83112b7 568 SMART SM00939 328 565 2.4E-55 T 29-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 SMALA_RS01720 791a6b83c1ea5a628132caa3c83112b7 568 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 54 313 7.8E-51 T 29-03-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 SMALA_RS36420 3e02ee96226f57a38ba56fdf4e21894f 269 SUPERFAMILY SSF53474 1 232 1.36E-48 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS36420 3e02ee96226f57a38ba56fdf4e21894f 269 Gene3D G3DSA:3.40.50.1820 1 238 8.4E-39 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS36420 3e02ee96226f57a38ba56fdf4e21894f 269 Pfam PF12697 Alpha/beta hydrolase family 1 228 7.1E-18 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 SUPERFAMILY SSF52151 3182 3306 2.62E-66 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 SUPERFAMILY SSF52151 3367 3463 2.62E-66 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 SUPERFAMILY SSF56801 7 507 5.49E-151 T 29-03-2018 SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 SMART SM00823 Phosphopantetheine attachment site 4553 4625 8.4E-35 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 SMART SM00823 Phosphopantetheine attachment site 887 956 1.4E-19 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 SMART SM00823 Phosphopantetheine attachment site 2578 2650 1.1E-28 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 Gene3D G3DSA:3.10.129.10 1884 2003 2.1E-8 T 29-03-2018 SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 Gene3D G3DSA:3.10.129.10 3534 3656 4.1E-6 T 29-03-2018 SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 SUPERFAMILY SSF51735 2088 2284 5.9E-17 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 Gene3D G3DSA:2.30.38.10 326 408 3.9E-27 T 29-03-2018 SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 SUPERFAMILY SSF47336 4546 4626 9.16E-23 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2665 2915 6.1E-90 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 978 1228 3.0E-92 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 SUPERFAMILY SSF51735 4272 4466 7.96E-42 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 SMART SM00826 3535 3691 1.6E-66 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 SMART SM00826 1881 2039 8.8E-61 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 Gene3D G3DSA:3.40.50.720 4271 4510 6.8E-46 T 29-03-2018 SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 Gene3D G3DSA:3.40.50.720 2298 2538 3.1E-49 T 29-03-2018 SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 Gene3D G3DSA:3.30.300.30 410 516 4.4E-24 T 29-03-2018 SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 Pfam PF00501 AMP-binding enzyme 15 415 1.4E-103 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 SUPERFAMILY SSF51735 4059 4195 5.3E-35 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 Pfam PF14765 Polyketide synthase dehydratase 1881 2147 5.9E-49 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 Pfam PF14765 Polyketide synthase dehydratase 3535 3801 1.1E-50 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 Pfam PF00698 Acyl transferase domain 1517 1831 3.6E-74 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 Pfam PF00698 Acyl transferase domain 3185 3488 2.3E-51 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 SMART SM01294 4554 4621 2.1E-6 T 29-03-2018 SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 SMART SM01294 2579 2646 1.0E-5 T 29-03-2018 SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 SUPERFAMILY SSF55048 1641 1703 4.05E-8 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 Gene3D G3DSA:3.90.180.10 3933 4270 7.8E-59 T 29-03-2018 SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 SMART SM00825 Beta-ketoacyl synthase 980 1405 1.3E-227 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 SMART SM00825 Beta-ketoacyl synthase 2667 3092 6.9E-210 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 Gene3D G3DSA:1.10.1200.10 874 976 3.0E-14 T 29-03-2018 SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 Gene3D G3DSA:1.10.1200.10 2571 2663 4.0E-18 T 29-03-2018 SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 3980 4035 1.5E-5 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 SUPERFAMILY SSF53901 2662 3036 1.97E-99 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 Gene3D G3DSA:3.40.47.10 1243 1403 4.6E-62 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 Gene3D G3DSA:3.40.47.10 2930 3090 2.2E-63 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 Gene3D G3DSA:3.40.50.980 175 325 1.2E-43 T 29-03-2018 SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 2828 2844 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 SUPERFAMILY SSF53901 975 1347 4.95E-104 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 SUPERFAMILY SSF52151 1710 1807 5.23E-66 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 SUPERFAMILY SSF52151 1514 1643 5.23E-66 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 Gene3D G3DSA:3.40.50.980 7 174 1.3E-41 T 29-03-2018 SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 Pfam PF13193 AMP-binding enzyme C-terminal domain 424 498 2.5E-16 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 SUPERFAMILY SSF51735 3745 3937 4.33E-17 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 Gene3D G3DSA:3.40.366.10 3173 3360 9.9E-55 T 29-03-2018 SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 SUPERFAMILY SSF51735 2296 2542 5.23E-43 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 SUPERFAMILY SSF47336 2572 2680 5.63E-22 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 3185 3469 1.1E-102 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1518 1843 2.5E-98 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 ProSitePatterns PS00455 Putative AMP-binding domain signature. 168 179 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 Gene3D G3DSA:3.40.50.720 668 790 2.6E-5 T 29-03-2018 SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 SUPERFAMILY SSF47336 884 993 1.83E-16 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 Pfam PF08659 KR domain 4275 4450 3.3E-59 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 Pfam PF08659 KR domain 2302 2476 3.6E-57 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 3041 3158 9.6E-14 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1354 1490 4.5E-13 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 SMART SM00829 3961 4267 1.7E-180 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 SUPERFAMILY SSF50129 3968 4093 1.73E-27 T 29-03-2018 IPR011032 GroES-like SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 SUPERFAMILY SSF51735 521 664 6.3E-11 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 Gene3D G3DSA:3.40.366.10 3361 3478 1.4E-20 T 29-03-2018 SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 Gene3D G3DSA:3.40.366.10 1504 1819 3.3E-74 T 29-03-2018 SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 Gene3D G3DSA:1.10.1200.10 4525 4627 3.9E-20 T 29-03-2018 SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 Pfam PF00550 Phosphopantetheine attachment site 4556 4621 1.1E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 Pfam PF00550 Phosphopantetheine attachment site 2581 2644 6.2E-9 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 Pfam PF00550 Phosphopantetheine attachment site 903 952 1.3E-6 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 Gene3D G3DSA:3.40.47.10 977 1240 1.4E-86 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 Gene3D G3DSA:3.40.47.10 2664 2927 2.5E-82 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1141 1157 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4275 4452 1.1E-51 T 29-03-2018 SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2301 2503 5.1E-48 T 29-03-2018 SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2923 3038 1.6E-44 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1236 1351 1.7E-43 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 Pfam PF13602 Zinc-binding dehydrogenase 4135 4267 7.3E-14 T 29-03-2018 SMALA_RS06435 0842b8bf64f147f71dd8c4b40c24c076 4714 SUPERFAMILY SSF55048 3305 3365 1.83E-8 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS08390 621fae7d5e00d301e0a3657bf4ca9bb9 114 SUPERFAMILY SSF47413 30 104 1.13E-14 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS08390 621fae7d5e00d301e0a3657bf4ca9bb9 114 Gene3D G3DSA:3.30.1190.10 64 111 1.0E-11 T 29-03-2018 SMALA_RS08390 621fae7d5e00d301e0a3657bf4ca9bb9 114 SMART SM00530 43 98 1.4E-10 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS08390 621fae7d5e00d301e0a3657bf4ca9bb9 114 Gene3D G3DSA:1.10.10.60 14 63 1.6E-8 T 29-03-2018 SMALA_RS08390 621fae7d5e00d301e0a3657bf4ca9bb9 114 Pfam PF13560 Helix-turn-helix domain 46 94 4.0E-11 T 29-03-2018 SMALA_RS18125 fb54ac7a5981346d3ce679fda4059a9f 381 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 61 370 20.568 T 29-03-2018 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 SMALA_RS18125 fb54ac7a5981346d3ce679fda4059a9f 381 SUPERFAMILY SSF82829 263 376 2.51E-14 T 29-03-2018 SMALA_RS18125 fb54ac7a5981346d3ce679fda4059a9f 381 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 73 254 4.1E-44 T 29-03-2018 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 SMALA_RS18125 fb54ac7a5981346d3ce679fda4059a9f 381 SUPERFAMILY SSF52402 73 283 6.55E-48 T 29-03-2018 SMALA_RS18125 fb54ac7a5981346d3ce679fda4059a9f 381 Pfam PF01171 PP-loop family 73 251 2.9E-39 T 29-03-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 SMALA_RS18125 fb54ac7a5981346d3ce679fda4059a9f 381 Gene3D G3DSA:3.40.50.620 72 293 1.9E-38 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS18125 fb54ac7a5981346d3ce679fda4059a9f 381 Pfam PF09179 TilS substrate binding domain 309 376 3.4E-10 T 29-03-2018 IPR015262 tRNA(Ile)-lysidine synthase , substrate-binding domain GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 SMALA_RS36600 87f9a6e19356c5dec2b6f417c8178454 277 Gene3D G3DSA:3.30.1490.20 93 154 2.4E-7 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SMALA_RS36600 87f9a6e19356c5dec2b6f417c8178454 277 Gene3D G3DSA:3.30.470.20 155 259 2.2E-13 T 29-03-2018 SMALA_RS36600 87f9a6e19356c5dec2b6f417c8178454 277 SUPERFAMILY SSF56059 79 264 1.99E-17 T 29-03-2018 SMALA_RS36600 87f9a6e19356c5dec2b6f417c8178454 277 Pfam PF08443 RimK-like ATP-grasp domain 122 251 1.2E-6 T 29-03-2018 IPR013651 ATP-grasp fold, RimK-type Reactome: R-HSA-70614 SMALA_RS36600 87f9a6e19356c5dec2b6f417c8178454 277 Gene3D G3DSA:3.40.50.20 1 92 1.0E-7 T 29-03-2018 SMALA_RS19660 ac8ea8c599e2d390a76e0ac86e20fb98 316 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 136 156 - T 29-03-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 SMALA_RS19660 ac8ea8c599e2d390a76e0ac86e20fb98 316 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 295 5.0E-49 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS19660 ac8ea8c599e2d390a76e0ac86e20fb98 316 Gene3D G3DSA:3.40.50.720 145 315 4.8E-31 T 29-03-2018 SMALA_RS19660 ac8ea8c599e2d390a76e0ac86e20fb98 316 SUPERFAMILY SSF51905 5 306 9.5E-55 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS19660 ac8ea8c599e2d390a76e0ac86e20fb98 316 Gene3D G3DSA:3.50.50.60 2 137 1.8E-22 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS19660 ac8ea8c599e2d390a76e0ac86e20fb98 316 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 1.1E-37 T 29-03-2018 SMALA_RS19660 ac8ea8c599e2d390a76e0ac86e20fb98 316 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 106 124 1.1E-37 T 29-03-2018 SMALA_RS19660 ac8ea8c599e2d390a76e0ac86e20fb98 316 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 232 248 1.1E-37 T 29-03-2018 SMALA_RS19660 ac8ea8c599e2d390a76e0ac86e20fb98 316 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 148 166 1.1E-37 T 29-03-2018 SMALA_RS19660 ac8ea8c599e2d390a76e0ac86e20fb98 316 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 259 281 1.1E-37 T 29-03-2018 SMALA_RS19660 ac8ea8c599e2d390a76e0ac86e20fb98 316 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 6 306 4.1E-122 T 29-03-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 SMALA_RS19660 ac8ea8c599e2d390a76e0ac86e20fb98 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 40 55 1.7E-80 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMALA_RS19660 ac8ea8c599e2d390a76e0ac86e20fb98 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 269 287 1.7E-80 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMALA_RS19660 ac8ea8c599e2d390a76e0ac86e20fb98 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 196 212 1.7E-80 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMALA_RS19660 ac8ea8c599e2d390a76e0ac86e20fb98 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 234 255 1.7E-80 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMALA_RS19660 ac8ea8c599e2d390a76e0ac86e20fb98 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 61 71 1.7E-80 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMALA_RS19660 ac8ea8c599e2d390a76e0ac86e20fb98 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 129 141 1.7E-80 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMALA_RS19660 ac8ea8c599e2d390a76e0ac86e20fb98 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 144 168 1.7E-80 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMALA_RS19660 ac8ea8c599e2d390a76e0ac86e20fb98 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 6 28 1.7E-80 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMALA_RS19660 ac8ea8c599e2d390a76e0ac86e20fb98 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 107 115 1.7E-80 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMALA_RS21445 f2aded8b6fddebab43ae9446cf9e6529 415 SUPERFAMILY SSF55718 311 415 4.71E-20 T 29-03-2018 IPR003033 SCP2 sterol-binding domain SMALA_RS21445 f2aded8b6fddebab43ae9446cf9e6529 415 Pfam PF13527 Acetyltransferase (GNAT) domain 9 132 1.3E-27 T 29-03-2018 SMALA_RS21445 f2aded8b6fddebab43ae9446cf9e6529 415 Gene3D G3DSA:3.30.1050.10 313 406 2.4E-22 T 29-03-2018 IPR003033 SCP2 sterol-binding domain SMALA_RS21445 f2aded8b6fddebab43ae9446cf9e6529 415 SUPERFAMILY SSF55729 30 308 9.08E-56 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS21445 f2aded8b6fddebab43ae9446cf9e6529 415 Pfam PF13530 Sterol carrier protein domain 184 412 3.7E-47 T 29-03-2018 IPR025559 Enhanced intracellular survival protein domain SMALA_RS21445 f2aded8b6fddebab43ae9446cf9e6529 415 Gene3D G3DSA:3.40.630.30 3 99 8.7E-9 T 29-03-2018 SMALA_RS21445 f2aded8b6fddebab43ae9446cf9e6529 415 Gene3D G3DSA:3.40.630.30 135 312 4.3E-48 T 29-03-2018 SMALA_RS21445 f2aded8b6fddebab43ae9446cf9e6529 415 Hamap MF_01812 UPF0256 protein . 2 415 31.048 T 29-03-2018 IPR022902 N-acetyltransferase Eis SMALA_RS28385 f784fc82c0d0aadb6fb4353fc1eaa53e 486 Pfam PF00171 Aldehyde dehydrogenase family 21 475 4.5E-131 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS28385 f784fc82c0d0aadb6fb4353fc1eaa53e 486 Gene3D G3DSA:3.40.605.10 2 270 4.7E-69 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS28385 f784fc82c0d0aadb6fb4353fc1eaa53e 486 SUPERFAMILY SSF53720 9 480 3.01E-129 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMALA_RS28385 f784fc82c0d0aadb6fb4353fc1eaa53e 486 Gene3D G3DSA:3.40.309.10 271 465 1.6E-58 T 29-03-2018 SMALA_RS04705 f480314b05f900795c175f18ba3bf255 428 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 110 135 - T 29-03-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 SMALA_RS04705 f480314b05f900795c175f18ba3bf255 428 SUPERFAMILY SSF54826 25 139 1.92E-24 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMALA_RS04705 f480314b05f900795c175f18ba3bf255 428 Gene3D G3DSA:3.30.390.10 22 124 5.9E-25 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMALA_RS04705 f480314b05f900795c175f18ba3bf255 428 SMART SM00922 153 279 6.1E-16 T 29-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal SMALA_RS04705 f480314b05f900795c175f18ba3bf255 428 Pfam PF13378 Enolase C-terminal domain-like 219 399 1.8E-38 T 29-03-2018 IPR029065 Enolase C-terminal domain-like SMALA_RS04705 f480314b05f900795c175f18ba3bf255 428 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 34 135 2.0E-17 T 29-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain SMALA_RS04705 f480314b05f900795c175f18ba3bf255 428 SUPERFAMILY SSF51604 123 407 9.83E-60 T 29-03-2018 IPR029065 Enolase C-terminal domain-like SMALA_RS04705 f480314b05f900795c175f18ba3bf255 428 Gene3D G3DSA:3.20.20.120 125 397 2.6E-57 T 29-03-2018 IPR029065 Enolase C-terminal domain-like SMALA_RS16860 27c208a306033a034086030396493dca 521 SMART SM00851 22 136 1.3E-47 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain SMALA_RS16860 27c208a306033a034086030396493dca 521 Gene3D G3DSA:3.40.140.20 236 367 4.3E-50 T 29-03-2018 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SMALA_RS16860 27c208a306033a034086030396493dca 521 SUPERFAMILY SSF52335 10 198 7.33E-63 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain SMALA_RS16860 27c208a306033a034086030396493dca 521 Pfam PF02142 MGS-like domain 22 135 1.5E-23 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain SMALA_RS16860 27c208a306033a034086030396493dca 521 PIRSF PIRSF000414 4 521 6.8E-197 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SMALA_RS16860 27c208a306033a034086030396493dca 521 SMART SM00798 141 455 3.0E-180 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SMALA_RS16860 27c208a306033a034086030396493dca 521 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 11 521 6.0E-172 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SMALA_RS16860 27c208a306033a034086030396493dca 521 Pfam PF01808 AICARFT/IMPCHase bienzyme 141 454 5.9E-112 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SMALA_RS16860 27c208a306033a034086030396493dca 521 Gene3D G3DSA:3.40.140.20 368 511 2.6E-49 T 29-03-2018 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SMALA_RS16860 27c208a306033a034086030396493dca 521 SUPERFAMILY SSF53927 219 521 1.4E-114 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 SMALA_RS16860 27c208a306033a034086030396493dca 521 Gene3D G3DSA:3.40.50.1380 1 198 1.7E-68 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain SMALA_RS16860 27c208a306033a034086030396493dca 521 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 10 521 41.728 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SMALA_RS32320 83ff5032830635e4de9621e6ee694f5e 397 SMART SM00388 164 232 6.8E-18 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS32320 83ff5032830635e4de9621e6ee694f5e 397 Gene3D G3DSA:3.30.450.20 48 169 6.2E-12 T 29-03-2018 SMALA_RS32320 83ff5032830635e4de9621e6ee694f5e 397 PRINTS PR00344 Bacterial sensor protein C-terminal signature 352 370 2.9E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS32320 83ff5032830635e4de9621e6ee694f5e 397 PRINTS PR00344 Bacterial sensor protein C-terminal signature 322 336 2.9E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS32320 83ff5032830635e4de9621e6ee694f5e 397 PRINTS PR00344 Bacterial sensor protein C-terminal signature 340 350 2.9E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS32320 83ff5032830635e4de9621e6ee694f5e 397 PRINTS PR00344 Bacterial sensor protein C-terminal signature 376 389 2.9E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS32320 83ff5032830635e4de9621e6ee694f5e 397 Pfam PF00512 His Kinase A (phospho-acceptor) domain 166 232 3.8E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS32320 83ff5032830635e4de9621e6ee694f5e 397 SUPERFAMILY SSF55874 222 390 8.25E-40 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS32320 83ff5032830635e4de9621e6ee694f5e 397 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 278 390 3.3E-23 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS32320 83ff5032830635e4de9621e6ee694f5e 397 SMART SM00387 277 392 1.5E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS32320 83ff5032830635e4de9621e6ee694f5e 397 Gene3D G3DSA:3.30.565.10 227 392 6.4E-38 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS32320 83ff5032830635e4de9621e6ee694f5e 397 SUPERFAMILY SSF55785 49 147 1.55E-9 T 29-03-2018 IPR000014 PAS domain SMALA_RS32320 83ff5032830635e4de9621e6ee694f5e 397 SUPERFAMILY SSF47384 155 233 1.02E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS32320 83ff5032830635e4de9621e6ee694f5e 397 Gene3D G3DSA:1.10.287.130 170 226 3.1E-14 T 29-03-2018 SMALA_RS01975 7551f47062c62ad5e60ab3e18d509a1b 312 SUPERFAMILY SSF161098 41 308 3.27E-68 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS01975 7551f47062c62ad5e60ab3e18d509a1b 312 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 127 304 4.8E-18 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS01975 7551f47062c62ad5e60ab3e18d509a1b 312 Gene3D G3DSA:1.10.3720.10 39 298 1.2E-37 T 29-03-2018 SMALA_RS35370 06ffeb7fb2572f8af1b2e3a07fb672fa 221 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 84 172 5.0E-9 T 29-03-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 SMALA_RS35370 06ffeb7fb2572f8af1b2e3a07fb672fa 221 Gene3D G3DSA:1.10.10.60 60 91 4.1E-10 T 29-03-2018 SMALA_RS35370 06ffeb7fb2572f8af1b2e3a07fb672fa 221 Gene3D G3DSA:1.10.10.60 1 59 1.0E-18 T 29-03-2018 SMALA_RS35370 06ffeb7fb2572f8af1b2e3a07fb672fa 221 SUPERFAMILY SSF46689 13 78 1.55E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS35370 06ffeb7fb2572f8af1b2e3a07fb672fa 221 Gene3D G3DSA:1.10.357.10 92 221 2.3E-14 T 29-03-2018 SMALA_RS35370 06ffeb7fb2572f8af1b2e3a07fb672fa 221 SUPERFAMILY SSF48498 83 193 3.78E-11 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS35370 06ffeb7fb2572f8af1b2e3a07fb672fa 221 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 70 1.2E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS29480 e4df024cba7df645acf7b3cf0871fb60 70 Gene3D G3DSA:3.90.820.10 2 68 1.8E-36 T 29-03-2018 SMALA_RS29480 e4df024cba7df645acf7b3cf0871fb60 70 SUPERFAMILY SSF160582 1 68 1.57E-32 T 29-03-2018 SMALA_RS29480 e4df024cba7df645acf7b3cf0871fb60 70 Pfam PF03621 MbtH-like protein 1 53 8.6E-30 T 29-03-2018 IPR005153 MbtH-like protein SMALA_RS29480 e4df024cba7df645acf7b3cf0871fb60 70 SMART SM00923 3 53 1.8E-32 T 29-03-2018 IPR005153 MbtH-like protein SMALA_RS22025 14fd19cee4670c6a625ae86e16ae2cc7 106 Pfam PF00893 Small Multidrug Resistance protein 1 93 2.4E-30 T 29-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 SMALA_RS22025 14fd19cee4670c6a625ae86e16ae2cc7 106 SUPERFAMILY SSF103481 6 100 8.5E-18 T 29-03-2018 SMALA_RS06840 981ef9e3b98c39c80c12d8858b0d9581 232 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 92 195 1.0E-8 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMALA_RS06840 981ef9e3b98c39c80c12d8858b0d9581 232 Pfam PF13419 Haloacid dehalogenase-like hydrolase 24 196 1.7E-32 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS06840 981ef9e3b98c39c80c12d8858b0d9581 232 SUPERFAMILY SSF56784 22 225 2.26E-51 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS06840 981ef9e3b98c39c80c12d8858b0d9581 232 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 141 157 1.5E-6 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMALA_RS06840 981ef9e3b98c39c80c12d8858b0d9581 232 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 159 179 1.5E-6 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMALA_RS06840 981ef9e3b98c39c80c12d8858b0d9581 232 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 21 32 1.5E-6 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMALA_RS06840 981ef9e3b98c39c80c12d8858b0d9581 232 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 110 123 1.5E-6 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMALA_RS06840 981ef9e3b98c39c80c12d8858b0d9581 232 Gene3D G3DSA:3.40.50.1000 9 211 2.1E-34 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS06840 981ef9e3b98c39c80c12d8858b0d9581 232 TIGRFAM TIGR01454 AHBA_synth_RP: AHBA synthesis associated protein 24 228 9.3E-106 T 29-03-2018 IPR006351 3-amino-5-hydroxybenzoic acid synthesis-related SMALA_RS06840 981ef9e3b98c39c80c12d8858b0d9581 232 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 98 188 8.9E-8 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMALA_RS42095 c0f6d22133203f9795b102c4688a6d19 662 SUPERFAMILY SSF51905 301 513 1.55E-32 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS42095 c0f6d22133203f9795b102c4688a6d19 662 SUPERFAMILY SSF51905 611 651 1.55E-32 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS42095 c0f6d22133203f9795b102c4688a6d19 662 Pfam PF01266 FAD dependent oxidoreductase 302 648 4.4E-33 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 SMALA_RS42095 c0f6d22133203f9795b102c4688a6d19 662 Gene3D G3DSA:3.40.50.2300 6 175 1.7E-15 T 29-03-2018 SMALA_RS42095 c0f6d22133203f9795b102c4688a6d19 662 Gene3D G3DSA:3.40.50.2300 176 241 0.26 T 29-03-2018 SMALA_RS42095 c0f6d22133203f9795b102c4688a6d19 662 SUPERFAMILY SSF53822 8 266 4.71E-24 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SMALA_RS42095 c0f6d22133203f9795b102c4688a6d19 662 Gene3D G3DSA:3.40.50.720 299 364 6.8E-7 T 29-03-2018 SMALA_RS42095 c0f6d22133203f9795b102c4688a6d19 662 Gene3D G3DSA:3.30.9.10 365 632 3.6E-22 T 29-03-2018 SMALA_RS10435 d5d02e16218a503d4762fd108a52ce4d 265 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 21 233 8.1E-11 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMALA_RS10435 d5d02e16218a503d4762fd108a52ce4d 265 Gene3D G3DSA:3.60.10.10 5 259 5.5E-24 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMALA_RS10435 d5d02e16218a503d4762fd108a52ce4d 265 SUPERFAMILY SSF56219 15 260 1.31E-25 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMALA_RS25160 7f8678edfb86e0141e80b9a88b22bbe3 278 SUPERFAMILY SSF51735 6 237 5.35E-45 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS25160 7f8678edfb86e0141e80b9a88b22bbe3 278 Gene3D G3DSA:3.40.50.720 1 278 2.9E-47 T 29-03-2018 SMALA_RS25160 7f8678edfb86e0141e80b9a88b22bbe3 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 1.3E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS25160 7f8678edfb86e0141e80b9a88b22bbe3 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 241 258 1.3E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS25160 7f8678edfb86e0141e80b9a88b22bbe3 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 1.3E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS25160 7f8678edfb86e0141e80b9a88b22bbe3 278 Pfam PF00106 short chain dehydrogenase 10 201 7.9E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS38760 92b8123a903bf4accdca03d2b920fed0 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 8.7E-17 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS38760 92b8123a903bf4accdca03d2b920fed0 307 Pfam PF03466 LysR substrate binding domain 89 289 6.1E-34 T 29-03-2018 IPR005119 LysR, substrate-binding SMALA_RS38760 92b8123a903bf4accdca03d2b920fed0 307 Gene3D G3DSA:1.10.10.10 1 87 3.1E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS38760 92b8123a903bf4accdca03d2b920fed0 307 Gene3D G3DSA:3.40.190.10 214 304 0.49 T 29-03-2018 SMALA_RS38760 92b8123a903bf4accdca03d2b920fed0 307 SUPERFAMILY SSF53850 91 292 3.98E-31 T 29-03-2018 SMALA_RS38760 92b8123a903bf4accdca03d2b920fed0 307 SUPERFAMILY SSF46785 2 111 1.05E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS38760 92b8123a903bf4accdca03d2b920fed0 307 Gene3D G3DSA:3.40.190.10 88 213 7.4E-24 T 29-03-2018 SMALA_RS33785 7522866928c36d3c99f051e92b6a2008 982 Gene3D G3DSA:2.60.40.10 579 690 3.8E-34 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS33785 7522866928c36d3c99f051e92b6a2008 982 SUPERFAMILY SSF49785 21 204 4.25E-57 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS33785 7522866928c36d3c99f051e92b6a2008 982 SMART SM01038 709 979 1.8E-107 T 29-03-2018 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 SMALA_RS33785 7522866928c36d3c99f051e92b6a2008 982 SUPERFAMILY SSF49303 208 285 1.69E-11 T 29-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 SMALA_RS33785 7522866928c36d3c99f051e92b6a2008 982 PRINTS PR00132 Glycosyl hydrolase family 2 signature 401 416 7.5E-32 T 29-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 SMALA_RS33785 7522866928c36d3c99f051e92b6a2008 982 PRINTS PR00132 Glycosyl hydrolase family 2 signature 132 147 7.5E-32 T 29-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 SMALA_RS33785 7522866928c36d3c99f051e92b6a2008 982 PRINTS PR00132 Glycosyl hydrolase family 2 signature 326 344 7.5E-32 T 29-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 SMALA_RS33785 7522866928c36d3c99f051e92b6a2008 982 PRINTS PR00132 Glycosyl hydrolase family 2 signature 295 309 7.5E-32 T 29-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 SMALA_RS33785 7522866928c36d3c99f051e92b6a2008 982 PRINTS PR00132 Glycosyl hydrolase family 2 signature 485 500 7.5E-32 T 29-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 SMALA_RS33785 7522866928c36d3c99f051e92b6a2008 982 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 37 204 8.1E-36 T 29-03-2018 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 SMALA_RS33785 7522866928c36d3c99f051e92b6a2008 982 Pfam PF02929 Beta galactosidase small chain 715 978 9.5E-62 T 29-03-2018 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 SMALA_RS33785 7522866928c36d3c99f051e92b6a2008 982 Pfam PF16353 Domain of unknown function(DUF4981) 598 685 4.9E-27 T 29-03-2018 IPR032312 Beta-galactosidase, domain 4 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 SMALA_RS33785 7522866928c36d3c99f051e92b6a2008 982 SUPERFAMILY SSF49303 575 688 3.02E-29 T 29-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 SMALA_RS33785 7522866928c36d3c99f051e92b6a2008 982 Gene3D G3DSA:2.70.98.10 700 980 1.5E-86 T 29-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 SMALA_RS33785 7522866928c36d3c99f051e92b6a2008 982 SUPERFAMILY SSF51445 286 577 3.83E-94 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS33785 7522866928c36d3c99f051e92b6a2008 982 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 287 583 5.1E-103 T 29-03-2018 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 SMALA_RS33785 7522866928c36d3c99f051e92b6a2008 982 SUPERFAMILY SSF74650 707 979 4.08E-78 T 29-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 SMALA_RS33785 7522866928c36d3c99f051e92b6a2008 982 Gene3D G3DSA:2.60.40.10 205 284 1.3E-4 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS33785 7522866928c36d3c99f051e92b6a2008 982 Gene3D G3DSA:3.20.20.80 285 578 2.3E-78 T 29-03-2018 SMALA_RS33785 7522866928c36d3c99f051e92b6a2008 982 Gene3D G3DSA:2.60.120.260 3 204 2.9E-54 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS33785 7522866928c36d3c99f051e92b6a2008 982 ProSitePatterns PS00608 Glycosyl hydrolases family 2 acid/base catalyst. 401 415 - T 29-03-2018 IPR023232 Glycoside hydrolase, family 2, active site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 SMALA_RS33785 7522866928c36d3c99f051e92b6a2008 982 ProSitePatterns PS00719 Glycosyl hydrolases family 2 signature 1. 336 361 - T 29-03-2018 IPR023230 Glycoside hydrolase, family 2, conserved site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 SMALA_RS16040 f2460e1a4d45f0119dcde2e945932ff9 395 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 7 389 4.7E-80 T 29-03-2018 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 SMALA_RS16040 f2460e1a4d45f0119dcde2e945932ff9 395 SUPERFAMILY SSF55031 206 315 5.76E-17 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain SMALA_RS16040 f2460e1a4d45f0119dcde2e945932ff9 395 PIRSF PIRSF001235 1 395 5.3E-119 T 29-03-2018 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 SMALA_RS16040 f2460e1a4d45f0119dcde2e945932ff9 395 Gene3D G3DSA:3.40.630.10 237 395 4.5E-19 T 29-03-2018 SMALA_RS16040 f2460e1a4d45f0119dcde2e945932ff9 395 Gene3D G3DSA:3.40.630.10 1 236 4.1E-35 T 29-03-2018 SMALA_RS16040 f2460e1a4d45f0119dcde2e945932ff9 395 Pfam PF01546 Peptidase family M20/M25/M40 67 390 2.9E-24 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 SMALA_RS16040 f2460e1a4d45f0119dcde2e945932ff9 395 SUPERFAMILY SSF53187 8 213 6.86E-69 T 29-03-2018 SMALA_RS16040 f2460e1a4d45f0119dcde2e945932ff9 395 SUPERFAMILY SSF53187 317 393 6.86E-69 T 29-03-2018 SMALA_RS00630 219df7a0462f2f979a9be3614412c650 370 SUPERFAMILY SSF56300 58 298 2.78E-32 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SMALA_RS00630 219df7a0462f2f979a9be3614412c650 370 SUPERFAMILY SSF56300 12 17 2.78E-32 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SMALA_RS00630 219df7a0462f2f979a9be3614412c650 370 Gene3D G3DSA:3.60.21.10 1 320 4.0E-44 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SMALA_RS00630 219df7a0462f2f979a9be3614412c650 370 SMART SM00854 7 288 1.3E-108 T 29-03-2018 IPR019079 Capsule synthesis protein, CapA SMALA_RS00630 219df7a0462f2f979a9be3614412c650 370 Pfam PF09587 Bacterial capsule synthesis protein PGA_cap 7 288 9.1E-74 T 29-03-2018 IPR019079 Capsule synthesis protein, CapA SMALA_RS25680 26b4409d8e32d776058183325fee377f 334 Gene3D G3DSA:1.10.3720.10 30 322 1.4E-47 T 29-03-2018 SMALA_RS25680 26b4409d8e32d776058183325fee377f 334 SUPERFAMILY SSF161098 114 318 3.79E-27 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS25680 26b4409d8e32d776058183325fee377f 334 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 29 70 1.1E-9 T 29-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain SMALA_RS25680 26b4409d8e32d776058183325fee377f 334 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 137 333 5.8E-30 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS02020 c91eb1e9e49180162d29679ddcc34bd8 451 SMART SM00387 302 403 5.4E-5 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS02020 c91eb1e9e49180162d29679ddcc34bd8 451 Gene3D G3DSA:3.30.565.10 210 402 8.8E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS02020 c91eb1e9e49180162d29679ddcc34bd8 451 Pfam PF07730 Histidine kinase 184 248 5.5E-11 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMALA_RS02020 c91eb1e9e49180162d29679ddcc34bd8 451 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 305 402 2.5E-5 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS02020 c91eb1e9e49180162d29679ddcc34bd8 451 SUPERFAMILY SSF55874 287 401 5.19E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS19310 8b9a5c98c6f6e0bb6d5e26d2243b35c3 413 TIGRFAM TIGR01412 tat_substr_1: Tat-translocated enzyme 5 412 1.3E-148 T 29-03-2018 IPR006313 Deferrochelatase/peroxidase EfeB GO:0004601|GO:0015684|GO:0020037|GO:0033212 SMALA_RS19310 8b9a5c98c6f6e0bb6d5e26d2243b35c3 413 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 64 401 5.0E-92 T 29-03-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 SMALA_RS19310 8b9a5c98c6f6e0bb6d5e26d2243b35c3 413 Pfam PF04261 Dyp-type peroxidase family 64 400 7.3E-104 T 29-03-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 SMALA_RS19310 8b9a5c98c6f6e0bb6d5e26d2243b35c3 413 SUPERFAMILY SSF54909 59 406 8.4E-82 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel SMALA_RS15850 8918c2bb4d6a29ca27e858fd3d0ff4a1 538 TIGRFAM TIGR00795 lctP: transporter, lactate permease (LctP) family 14 528 8.3E-137 T 29-03-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 SMALA_RS15850 8918c2bb4d6a29ca27e858fd3d0ff4a1 538 Pfam PF02652 L-lactate permease 15 526 3.5E-137 T 29-03-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 SMALA_RS37685 a234cd93e984fcac6c282896b5c93347 270 Pfam PF03704 Bacterial transcriptional activator domain 124 226 1.1E-25 T 29-03-2018 IPR005158 Bacterial transcriptional activator domain SMALA_RS37685 a234cd93e984fcac6c282896b5c93347 270 Gene3D G3DSA:1.25.40.10 30 257 3.5E-13 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS37685 a234cd93e984fcac6c282896b5c93347 270 SUPERFAMILY SSF48452 126 228 1.29E-22 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS37685 a234cd93e984fcac6c282896b5c93347 270 SMART SM01043 90 231 7.7E-25 T 29-03-2018 IPR005158 Bacterial transcriptional activator domain SMALA_RS28465 79b6ec3dafed0b7b70997c66f728e55e 330 SUPERFAMILY SSF54814 180 258 2.09E-27 T 29-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 SMALA_RS28465 79b6ec3dafed0b7b70997c66f728e55e 330 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 5 322 4.9E-105 T 29-03-2018 IPR010213 Transcription termination factor NusA GO:0003723 SMALA_RS28465 79b6ec3dafed0b7b70997c66f728e55e 330 Gene3D G3DSA:3.30.300.20 258 329 5.9E-17 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta SMALA_RS28465 79b6ec3dafed0b7b70997c66f728e55e 330 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 1 330 25.753 T 29-03-2018 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 SMALA_RS28465 79b6ec3dafed0b7b70997c66f728e55e 330 SUPERFAMILY SSF54814 259 324 1.96E-15 T 29-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 SMALA_RS28465 79b6ec3dafed0b7b70997c66f728e55e 330 Pfam PF13184 NusA-like KH domain 210 277 3.6E-26 T 29-03-2018 IPR025249 KH domain, NusA-like GO:0003723 SMALA_RS28465 79b6ec3dafed0b7b70997c66f728e55e 330 SUPERFAMILY SSF50249 112 179 6.86E-14 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMALA_RS28465 79b6ec3dafed0b7b70997c66f728e55e 330 Gene3D G3DSA:2.40.50.140 115 178 2.5E-12 T 29-03-2018 SMALA_RS28465 79b6ec3dafed0b7b70997c66f728e55e 330 Gene3D G3DSA:3.30.300.20 179 256 2.2E-32 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta SMALA_RS28465 79b6ec3dafed0b7b70997c66f728e55e 330 Pfam PF08529 NusA N-terminal domain 6 103 1.5E-16 T 29-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 SMALA_RS28465 79b6ec3dafed0b7b70997c66f728e55e 330 SUPERFAMILY SSF69705 3 102 2.75E-27 T 29-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 SMALA_RS28465 79b6ec3dafed0b7b70997c66f728e55e 330 Gene3D G3DSA:3.30.1480.10 1 102 7.0E-30 T 29-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 SMALA_RS01850 13cf71277b198f4f99feba8f064cd609 301 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 87 1.1E-8 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS01850 13cf71277b198f4f99feba8f064cd609 301 Pfam PF13602 Zinc-binding dehydrogenase 193 299 3.7E-14 T 29-03-2018 SMALA_RS01850 13cf71277b198f4f99feba8f064cd609 301 SUPERFAMILY SSF51735 111 297 1.19E-24 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS01850 13cf71277b198f4f99feba8f064cd609 301 SMART SM00829 10 299 4.8E-17 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS01850 13cf71277b198f4f99feba8f064cd609 301 Gene3D G3DSA:3.90.180.10 1 301 3.3E-63 T 29-03-2018 SMALA_RS01850 13cf71277b198f4f99feba8f064cd609 301 SUPERFAMILY SSF50129 1 147 2.89E-36 T 29-03-2018 IPR011032 GroES-like SMALA_RS14505 29a7f7f441651cde8505a020bcc9b4a1 433 SUPERFAMILY SSF53756 261 429 2.24E-39 T 29-03-2018 SMALA_RS14505 29a7f7f441651cde8505a020bcc9b4a1 433 SUPERFAMILY SSF53756 2 233 2.24E-39 T 29-03-2018 SMALA_RS14505 29a7f7f441651cde8505a020bcc9b4a1 433 Gene3D G3DSA:3.40.50.2000 207 413 3.9E-12 T 29-03-2018 SMALA_RS14505 29a7f7f441651cde8505a020bcc9b4a1 433 Gene3D G3DSA:3.40.50.2000 1 206 4.8E-32 T 29-03-2018 SMALA_RS01985 55c8c66ab350a019386eff152034f342 876 Pfam PF08448 PAS fold 216 313 3.0E-8 T 29-03-2018 IPR013656 PAS fold-4 SMALA_RS01985 55c8c66ab350a019386eff152034f342 876 SUPERFAMILY SSF55781 346 495 1.31E-16 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS01985 55c8c66ab350a019386eff152034f342 876 SUPERFAMILY SSF55785 218 317 1.43E-9 T 29-03-2018 IPR000014 PAS domain SMALA_RS01985 55c8c66ab350a019386eff152034f342 876 SUPERFAMILY SSF81606 529 687 2.07E-6 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS01985 55c8c66ab350a019386eff152034f342 876 SMART SM00065 331 493 0.0077 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS01985 55c8c66ab350a019386eff152034f342 876 Pfam PF13185 GAF domain 343 484 9.3E-12 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS01985 55c8c66ab350a019386eff152034f342 876 Gene3D G3DSA:3.30.450.40 11 188 6.2E-8 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS01985 55c8c66ab350a019386eff152034f342 876 SMART SM00331 514 741 2.3E-37 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS01985 55c8c66ab350a019386eff152034f342 876 Gene3D G3DSA:3.30.450.40 318 492 4.7E-27 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS01985 55c8c66ab350a019386eff152034f342 876 SUPERFAMILY SSF55781 53 187 3.44E-5 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS01985 55c8c66ab350a019386eff152034f342 876 Gene3D G3DSA:3.30.565.10 745 874 3.2E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS01985 55c8c66ab350a019386eff152034f342 876 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 541 741 4.0E-50 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS01985 55c8c66ab350a019386eff152034f342 876 Gene3D G3DSA:3.30.450.20 209 317 3.7E-16 T 29-03-2018 SMALA_RS01985 55c8c66ab350a019386eff152034f342 876 Gene3D G3DSA:3.60.40.10 493 744 1.6E-41 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS10670 7be22dc587b4b0ee4dc48483aaf8a683 891 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 15 891 0.0 T 29-03-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 SMALA_RS10670 7be22dc587b4b0ee4dc48483aaf8a683 891 PIRSF PIRSF000156 6 891 0.0 T 29-03-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 SMALA_RS10670 7be22dc587b4b0ee4dc48483aaf8a683 891 Gene3D G3DSA:3.40.50.970 65 480 4.0E-72 T 29-03-2018 SMALA_RS10670 7be22dc587b4b0ee4dc48483aaf8a683 891 Gene3D G3DSA:3.40.50.920 720 891 5.1E-39 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMALA_RS10670 7be22dc587b4b0ee4dc48483aaf8a683 891 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 147 299 3.6E-10 T 29-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SMALA_RS10670 7be22dc587b4b0ee4dc48483aaf8a683 891 SUPERFAMILY SSF52518 484 711 9.71E-88 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold SMALA_RS10670 7be22dc587b4b0ee4dc48483aaf8a683 891 SUPERFAMILY SSF52922 716 891 1.92E-50 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMALA_RS10670 7be22dc587b4b0ee4dc48483aaf8a683 891 SUPERFAMILY SSF52518 67 477 1.72E-114 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold SMALA_RS10670 7be22dc587b4b0ee4dc48483aaf8a683 891 Gene3D G3DSA:3.40.50.970 482 717 1.8E-64 T 29-03-2018 SMALA_RS15005 3e15776d3a01c8672c02a712d54c3404 131 Gene3D G3DSA:1.20.1480.30 26 110 3.6E-5 T 29-03-2018 SMALA_RS07040 822c17a3ce1a109c629bcf8a101c8eb8 527 SUPERFAMILY SSF51905 462 523 2.9E-55 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS07040 822c17a3ce1a109c629bcf8a101c8eb8 527 SUPERFAMILY SSF51905 28 324 2.9E-55 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS07040 822c17a3ce1a109c629bcf8a101c8eb8 527 Pfam PF00732 GMC oxidoreductase 186 303 1.3E-12 T 29-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 SMALA_RS07040 822c17a3ce1a109c629bcf8a101c8eb8 527 Gene3D G3DSA:3.50.50.60 23 527 4.5E-58 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS07040 822c17a3ce1a109c629bcf8a101c8eb8 527 Pfam PF05199 GMC oxidoreductase 457 517 1.4E-16 T 29-03-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 SMALA_RS07040 822c17a3ce1a109c629bcf8a101c8eb8 527 ProSitePatterns PS00221 MIP family signature. 503 511 - T 29-03-2018 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMALA_RS07040 822c17a3ce1a109c629bcf8a101c8eb8 527 Pfam PF13450 NAD(P)-binding Rossmann-like domain 34 61 2.2E-5 T 29-03-2018 SMALA_RS40105 d2394a7b77ee902ba2e16a6db720521a 307 Pfam PF03466 LysR substrate binding domain 88 294 3.4E-30 T 29-03-2018 IPR005119 LysR, substrate-binding SMALA_RS40105 d2394a7b77ee902ba2e16a6db720521a 307 SUPERFAMILY SSF53850 89 298 4.34E-30 T 29-03-2018 SMALA_RS40105 d2394a7b77ee902ba2e16a6db720521a 307 SUPERFAMILY SSF46785 1 83 1.26E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS40105 d2394a7b77ee902ba2e16a6db720521a 307 Gene3D G3DSA:3.40.190.10 89 177 3.0E-13 T 29-03-2018 SMALA_RS40105 d2394a7b77ee902ba2e16a6db720521a 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.9E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS40105 d2394a7b77ee902ba2e16a6db720521a 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.9E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS40105 d2394a7b77ee902ba2e16a6db720521a 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.9E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS40105 d2394a7b77ee902ba2e16a6db720521a 307 Gene3D G3DSA:1.10.10.10 1 83 3.7E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS40105 d2394a7b77ee902ba2e16a6db720521a 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 3.4E-20 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS40105 d2394a7b77ee902ba2e16a6db720521a 307 Gene3D G3DSA:3.40.190.10 178 266 4.6E-14 T 29-03-2018 SMALA_RS14150 dae546d1a57b8c37d5073e6f4948a7ee 207 SUPERFAMILY SSF46689 10 77 1.16E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS14150 dae546d1a57b8c37d5073e6f4948a7ee 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 68 1.2E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS14150 dae546d1a57b8c37d5073e6f4948a7ee 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 24 37 1.2E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS14150 dae546d1a57b8c37d5073e6f4948a7ee 207 Gene3D G3DSA:1.10.260.40 46 85 8.8E-9 T 29-03-2018 SMALA_RS14150 dae546d1a57b8c37d5073e6f4948a7ee 207 SUPERFAMILY SSF48498 84 199 1.03E-17 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS14150 dae546d1a57b8c37d5073e6f4948a7ee 207 Gene3D G3DSA:1.10.357.10 86 204 1.1E-15 T 29-03-2018 SMALA_RS14150 dae546d1a57b8c37d5073e6f4948a7ee 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 70 5.8E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS14150 dae546d1a57b8c37d5073e6f4948a7ee 207 Gene3D G3DSA:1.10.10.60 2 45 1.5E-12 T 29-03-2018 SMALA_RS14150 dae546d1a57b8c37d5073e6f4948a7ee 207 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 88 201 1.5E-12 T 29-03-2018 SMALA_RS27815 14ecfa50ca60090ba58eb52a4b443d6a 527 SUPERFAMILY SSF52096 14 267 7.55E-74 T 29-03-2018 IPR029045 ClpP/crotonase-like domain SMALA_RS27815 14ecfa50ca60090ba58eb52a4b443d6a 527 Gene3D G3DSA:3.90.226.10 3 266 3.9E-78 T 29-03-2018 SMALA_RS27815 14ecfa50ca60090ba58eb52a4b443d6a 527 Gene3D G3DSA:3.90.226.10 267 524 1.6E-74 T 29-03-2018 SMALA_RS27815 14ecfa50ca60090ba58eb52a4b443d6a 527 SUPERFAMILY SSF52096 254 526 1.06E-88 T 29-03-2018 IPR029045 ClpP/crotonase-like domain SMALA_RS27815 14ecfa50ca60090ba58eb52a4b443d6a 527 Pfam PF01039 Carboxyl transferase domain 40 524 3.2E-196 T 29-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 SMALA_RS04425 d2086e4ee51c1f0cd7cad43fe66ed14a 237 SUPERFAMILY SSF56784 4 213 1.95E-35 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS04425 d2086e4ee51c1f0cd7cad43fe66ed14a 237 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 89 210 2.3E-8 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMALA_RS04425 d2086e4ee51c1f0cd7cad43fe66ed14a 237 Pfam PF13419 Haloacid dehalogenase-like hydrolase 96 209 7.5E-13 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS04425 d2086e4ee51c1f0cd7cad43fe66ed14a 237 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 116 202 3.9E-7 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMALA_RS04425 d2086e4ee51c1f0cd7cad43fe66ed14a 237 Gene3D G3DSA:3.40.50.1000 2 224 2.2E-25 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS04425 d2086e4ee51c1f0cd7cad43fe66ed14a 237 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 3 14 1.3E-11 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMALA_RS04425 d2086e4ee51c1f0cd7cad43fe66ed14a 237 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 200 213 1.3E-11 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMALA_RS04425 d2086e4ee51c1f0cd7cad43fe66ed14a 237 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 173 193 1.3E-11 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMALA_RS04425 d2086e4ee51c1f0cd7cad43fe66ed14a 237 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 125 138 1.3E-11 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMALA_RS04425 d2086e4ee51c1f0cd7cad43fe66ed14a 237 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 155 171 1.3E-11 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMALA_RS07315 152ed3aa195f1f4f42b35c42caf7302d 264 Pfam PF09339 IclR helix-turn-helix domain 17 67 8.6E-17 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMALA_RS07315 152ed3aa195f1f4f42b35c42caf7302d 264 Gene3D G3DSA:3.30.450.40 85 263 1.2E-44 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS07315 152ed3aa195f1f4f42b35c42caf7302d 264 Gene3D G3DSA:1.10.10.10 9 84 8.7E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS07315 152ed3aa195f1f4f42b35c42caf7302d 264 SMART SM00346 15 105 7.7E-36 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMALA_RS07315 152ed3aa195f1f4f42b35c42caf7302d 264 Pfam PF01614 Bacterial transcriptional regulator 133 257 1.4E-29 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal SMALA_RS07315 152ed3aa195f1f4f42b35c42caf7302d 264 SUPERFAMILY SSF46785 15 87 5.38E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS07315 152ed3aa195f1f4f42b35c42caf7302d 264 SUPERFAMILY SSF55781 81 260 3.27E-35 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS20925 c5db1f14d831015f1b1ab42a87198856 519 Pfam PF13522 Glutamine amidotransferase domain 84 227 9.0E-15 T 29-03-2018 SMALA_RS20925 c5db1f14d831015f1b1ab42a87198856 519 Gene3D G3DSA:3.60.20.10 23 260 1.2E-60 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SMALA_RS20925 c5db1f14d831015f1b1ab42a87198856 519 Pfam PF00156 Phosphoribosyl transferase domain 298 403 1.3E-7 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 SMALA_RS20925 c5db1f14d831015f1b1ab42a87198856 519 Gene3D G3DSA:3.40.50.2020 261 459 1.4E-30 T 29-03-2018 SMALA_RS20925 c5db1f14d831015f1b1ab42a87198856 519 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 22 473 46.135 T 29-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 SMALA_RS20925 c5db1f14d831015f1b1ab42a87198856 519 SUPERFAMILY SSF53271 268 483 3.02E-67 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like SMALA_RS20925 c5db1f14d831015f1b1ab42a87198856 519 PIRSF PIRSF000485 19 485 1.2E-158 T 29-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 SMALA_RS20925 c5db1f14d831015f1b1ab42a87198856 519 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 23 474 3.6E-155 T 29-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 SMALA_RS20925 c5db1f14d831015f1b1ab42a87198856 519 SUPERFAMILY SSF56235 23 286 6.18E-64 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SMALA_RS25815 e45c91f32241157057bec722c891e70d 271 Gene3D G3DSA:1.10.10.10 148 241 4.8E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS25815 e45c91f32241157057bec722c891e70d 271 Pfam PF08281 Sigma-70, region 4 183 234 8.3E-17 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS25815 e45c91f32241157057bec722c891e70d 271 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 81 238 5.2E-33 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS25815 e45c91f32241157057bec722c891e70d 271 SUPERFAMILY SSF88946 81 161 1.08E-23 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS25815 e45c91f32241157057bec722c891e70d 271 SUPERFAMILY SSF88659 179 239 2.8E-17 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS25815 e45c91f32241157057bec722c891e70d 271 Gene3D G3DSA:1.10.1740.10 68 147 8.3E-23 T 29-03-2018 SMALA_RS25815 e45c91f32241157057bec722c891e70d 271 Pfam PF04542 Sigma-70 region 2 85 150 6.4E-21 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS14610 560194f86cc82dc2a35d8d9c7e4f08c2 250 TIGRFAM TIGR03004 ectoine_ehuC: ectoine/hydroxyectoine ABC transporter, permease protein EhuC 10 214 1.7E-73 T 29-03-2018 IPR014342 Ectoine/hydroxyectoine ABC transporter, permease protein EhuC SMALA_RS14610 560194f86cc82dc2a35d8d9c7e4f08c2 250 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 31 211 8.6E-15 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS14610 560194f86cc82dc2a35d8d9c7e4f08c2 250 SUPERFAMILY SSF161098 8 196 8.11E-39 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS14610 560194f86cc82dc2a35d8d9c7e4f08c2 250 Gene3D G3DSA:1.10.3720.10 3 213 9.0E-38 T 29-03-2018 SMALA_RS14610 560194f86cc82dc2a35d8d9c7e4f08c2 250 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 10 105 2.6E-22 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 SMALA_RS38130 2e43f989fed3d99b02dc818cb16c6ef7 484 Gene3D G3DSA:3.30.360.10 300 456 6.6E-46 T 29-03-2018 SMALA_RS38130 2e43f989fed3d99b02dc818cb16c6ef7 484 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 290 297 - T 29-03-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMALA_RS38130 2e43f989fed3d99b02dc818cb16c6ef7 484 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 297 454 1.6E-42 T 29-03-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMALA_RS38130 2e43f989fed3d99b02dc818cb16c6ef7 484 SUPERFAMILY SSF51735 130 308 3.41E-44 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS38130 2e43f989fed3d99b02dc818cb16c6ef7 484 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 130 243 3.9E-20 T 29-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMALA_RS38130 2e43f989fed3d99b02dc818cb16c6ef7 484 Gene3D G3DSA:3.40.50.720 128 299 9.4E-49 T 29-03-2018 SMALA_RS38130 2e43f989fed3d99b02dc818cb16c6ef7 484 SUPERFAMILY SSF55347 292 455 1.85E-48 T 29-03-2018 SMALA_RS38130 2e43f989fed3d99b02dc818cb16c6ef7 484 SMART SM00846 129 292 3.0E-50 T 29-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMALA_RS38130 2e43f989fed3d99b02dc818cb16c6ef7 484 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 250 263 2.6E-18 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMALA_RS38130 2e43f989fed3d99b02dc818cb16c6ef7 484 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 286 304 2.6E-18 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMALA_RS38130 2e43f989fed3d99b02dc818cb16c6ef7 484 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 369 386 2.6E-18 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMALA_RS38130 2e43f989fed3d99b02dc818cb16c6ef7 484 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 313 329 2.6E-18 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMALA_RS22760 958240121d056e92fb627455995cc133 325 SUPERFAMILY SSF52540 10 323 1.13E-70 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS22760 958240121d056e92fb627455995cc133 325 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 98 241 4.5E-10 T 29-03-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 Reactome: R-HSA-73614 SMALA_RS22760 958240121d056e92fb627455995cc133 325 PIRSF PIRSF000545 5 325 1.5E-143 T 29-03-2018 IPR004566 Pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 SMALA_RS22760 958240121d056e92fb627455995cc133 325 Gene3D G3DSA:3.40.50.300 11 324 4.5E-58 T 29-03-2018 SMALA_RS22760 958240121d056e92fb627455995cc133 325 Hamap MF_00215 Pantothenate kinase [coaA]. 1 325 174.534 T 29-03-2018 IPR004566 Pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 SMALA_RS22760 958240121d056e92fb627455995cc133 325 TIGRFAM TIGR00554 panK_bact: pantothenate kinase 12 324 6.9E-125 T 29-03-2018 IPR004566 Pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 SMALA_RS24545 b05f1afc8100c615af4fdec2bf9c7723 510 SUPERFAMILY SSF52540 152 433 1.4E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS24545 b05f1afc8100c615af4fdec2bf9c7723 510 Pfam PF00271 Helicase conserved C-terminal domain 315 415 8.5E-25 T 29-03-2018 IPR001650 Helicase, C-terminal SMALA_RS24545 b05f1afc8100c615af4fdec2bf9c7723 510 Pfam PF00270 DEAD/DEAH box helicase 105 274 1.2E-41 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 SMALA_RS24545 b05f1afc8100c615af4fdec2bf9c7723 510 SMART SM00490 334 415 2.6E-28 T 29-03-2018 IPR001650 Helicase, C-terminal SMALA_RS24545 b05f1afc8100c615af4fdec2bf9c7723 510 Gene3D G3DSA:3.40.50.300 302 508 7.4E-38 T 29-03-2018 SMALA_RS24545 b05f1afc8100c615af4fdec2bf9c7723 510 SMART SM00487 100 300 3.5E-47 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain SMALA_RS24545 b05f1afc8100c615af4fdec2bf9c7723 510 Gene3D G3DSA:3.40.50.300 80 301 2.5E-48 T 29-03-2018 SMALA_RS04835 2fc66f161ede61f97a964228200c2ba8 139 Gene3D G3DSA:3.30.530.20 2 139 1.8E-25 T 29-03-2018 IPR023393 START-like domain SMALA_RS04835 2fc66f161ede61f97a964228200c2ba8 139 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 1 137 3.2E-25 T 29-03-2018 IPR019587 Polyketide cyclase/dehydrase SMALA_RS04835 2fc66f161ede61f97a964228200c2ba8 139 SUPERFAMILY SSF55961 1 135 7.19E-31 T 29-03-2018 SMALA_RS32415 56899ee459a0f05318f5cc61872aceef 190 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 23 186 9.0E-25 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SMALA_RS32415 56899ee459a0f05318f5cc61872aceef 190 SUPERFAMILY SSF53254 4 186 9.42E-31 T 29-03-2018 IPR029033 Histidine phosphatase superfamily SMALA_RS32415 56899ee459a0f05318f5cc61872aceef 190 Gene3D G3DSA:3.40.50.1240 2 188 3.7E-23 T 29-03-2018 IPR029033 Histidine phosphatase superfamily SMALA_RS32415 56899ee459a0f05318f5cc61872aceef 190 SMART SM00855 4 151 8.1E-8 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SMALA_RS35225 dc9df8d297c025ecf196158a541ba652 280 PRINTS PR01438 Universal stress protein signature 114 136 9.8E-9 T 29-03-2018 IPR006015 Universal stress protein A SMALA_RS35225 dc9df8d297c025ecf196158a541ba652 280 PRINTS PR01438 Universal stress protein signature 2 20 9.8E-9 T 29-03-2018 IPR006015 Universal stress protein A SMALA_RS35225 dc9df8d297c025ecf196158a541ba652 280 PRINTS PR01438 Universal stress protein signature 96 108 9.8E-9 T 29-03-2018 IPR006015 Universal stress protein A SMALA_RS35225 dc9df8d297c025ecf196158a541ba652 280 Pfam PF00582 Universal stress protein family 3 136 1.5E-19 T 29-03-2018 IPR006016 UspA GO:0006950 SMALA_RS35225 dc9df8d297c025ecf196158a541ba652 280 Pfam PF00582 Universal stress protein family 148 278 3.8E-12 T 29-03-2018 IPR006016 UspA GO:0006950 SMALA_RS35225 dc9df8d297c025ecf196158a541ba652 280 SUPERFAMILY SSF52402 146 278 4.35E-14 T 29-03-2018 SMALA_RS35225 dc9df8d297c025ecf196158a541ba652 280 SUPERFAMILY SSF52402 4 142 2.09E-24 T 29-03-2018 SMALA_RS35225 dc9df8d297c025ecf196158a541ba652 280 Gene3D G3DSA:3.40.50.620 143 277 6.2E-20 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS35225 dc9df8d297c025ecf196158a541ba652 280 Gene3D G3DSA:3.40.50.620 2 142 3.6E-29 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS30400 44ad6d86a2c4e5a393c3899a510ed828 599 Gene3D G3DSA:3.40.50.280 45 195 0.0053 T 29-03-2018 SMALA_RS30400 44ad6d86a2c4e5a393c3899a510ed828 599 Gene3D G3DSA:3.80.30.20 252 504 9.5E-23 T 29-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe SMALA_RS30400 44ad6d86a2c4e5a393c3899a510ed828 599 SUPERFAMILY SSF102114 248 547 1.96E-25 T 29-03-2018 SMALA_RS30400 44ad6d86a2c4e5a393c3899a510ed828 599 Pfam PF04055 Radical SAM superfamily 261 440 2.2E-7 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 SMALA_RS30400 44ad6d86a2c4e5a393c3899a510ed828 599 SMART SM00729 255 486 3.0E-12 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 SMALA_RS35235 96c10db0e7a16798381c64f7759ccf79 284 PRINTS PR01438 Universal stress protein signature 2 20 2.8E-9 T 29-03-2018 IPR006015 Universal stress protein A SMALA_RS35235 96c10db0e7a16798381c64f7759ccf79 284 PRINTS PR01438 Universal stress protein signature 114 136 2.8E-9 T 29-03-2018 IPR006015 Universal stress protein A SMALA_RS35235 96c10db0e7a16798381c64f7759ccf79 284 PRINTS PR01438 Universal stress protein signature 96 108 2.8E-9 T 29-03-2018 IPR006015 Universal stress protein A SMALA_RS35235 96c10db0e7a16798381c64f7759ccf79 284 Pfam PF00582 Universal stress protein family 147 282 1.1E-10 T 29-03-2018 IPR006016 UspA GO:0006950 SMALA_RS35235 96c10db0e7a16798381c64f7759ccf79 284 Pfam PF00582 Universal stress protein family 1 136 2.1E-21 T 29-03-2018 IPR006016 UspA GO:0006950 SMALA_RS35235 96c10db0e7a16798381c64f7759ccf79 284 Gene3D G3DSA:3.40.50.620 1 142 3.7E-30 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS35235 96c10db0e7a16798381c64f7759ccf79 284 SUPERFAMILY SSF52402 147 282 1.76E-16 T 29-03-2018 SMALA_RS35235 96c10db0e7a16798381c64f7759ccf79 284 SUPERFAMILY SSF52402 3 140 1.17E-23 T 29-03-2018 SMALA_RS35235 96c10db0e7a16798381c64f7759ccf79 284 Gene3D G3DSA:3.40.50.620 143 284 4.2E-18 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS30005 07c9ee032e4b7dc99c71962259c29466 373 SUPERFAMILY SSF52540 98 212 1.91E-7 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS30005 07c9ee032e4b7dc99c71962259c29466 373 Gene3D G3DSA:3.40.50.300 34 281 2.6E-6 T 29-03-2018 SMALA_RS30005 07c9ee032e4b7dc99c71962259c29466 373 Pfam PF03969 AFG1-like ATPase 61 246 1.5E-40 T 29-03-2018 IPR005654 ATPase, AFG1-like GO:0005524 SMALA_RS30005 07c9ee032e4b7dc99c71962259c29466 373 Pfam PF03969 AFG1-like ATPase 260 360 6.0E-14 T 29-03-2018 IPR005654 ATPase, AFG1-like GO:0005524 SMALA_RS39855 7fab8933bd716b8ac0ab7a6d7165aa16 325 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 217 323 1.3E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS39855 7fab8933bd716b8ac0ab7a6d7165aa16 325 Pfam PF00512 His Kinase A (phospho-acceptor) domain 110 176 8.9E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS39855 7fab8933bd716b8ac0ab7a6d7165aa16 325 Gene3D G3DSA:3.30.565.10 180 325 4.4E-33 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS39855 7fab8933bd716b8ac0ab7a6d7165aa16 325 PRINTS PR00344 Bacterial sensor protein C-terminal signature 269 279 5.5E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS39855 7fab8933bd716b8ac0ab7a6d7165aa16 325 PRINTS PR00344 Bacterial sensor protein C-terminal signature 285 303 5.5E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS39855 7fab8933bd716b8ac0ab7a6d7165aa16 325 PRINTS PR00344 Bacterial sensor protein C-terminal signature 251 265 5.5E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS39855 7fab8933bd716b8ac0ab7a6d7165aa16 325 PRINTS PR00344 Bacterial sensor protein C-terminal signature 309 322 5.5E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS39855 7fab8933bd716b8ac0ab7a6d7165aa16 325 SUPERFAMILY SSF55874 167 323 1.05E-33 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS39855 7fab8933bd716b8ac0ab7a6d7165aa16 325 SMART SM00388 109 176 2.2E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS39855 7fab8933bd716b8ac0ab7a6d7165aa16 325 SUPERFAMILY SSF47384 105 176 2.55E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS39855 7fab8933bd716b8ac0ab7a6d7165aa16 325 Gene3D G3DSA:1.10.287.130 100 172 1.6E-13 T 29-03-2018 SMALA_RS39855 7fab8933bd716b8ac0ab7a6d7165aa16 325 SMART SM00387 216 325 7.4E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS32905 009419ae6f7b74a5c78c00550e7bbad6 250 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 3 240 34.114 T 29-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMALA_RS32905 009419ae6f7b74a5c78c00550e7bbad6 250 SUPERFAMILY SSF75625 3 247 1.7E-88 T 29-03-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMALA_RS32905 009419ae6f7b74a5c78c00550e7bbad6 250 Gene3D G3DSA:1.10.10.200 1 78 5.6E-28 T 29-03-2018 IPR017856 Integrase, N-terminal zinc-binding domain-like SMALA_RS32905 009419ae6f7b74a5c78c00550e7bbad6 250 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 238 2.4E-97 T 29-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMALA_RS32905 009419ae6f7b74a5c78c00550e7bbad6 250 Pfam PF01709 Transcriptional regulator 5 238 2.5E-89 T 29-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMALA_RS32905 009419ae6f7b74a5c78c00550e7bbad6 250 Gene3D G3DSA:3.30.70.980 180 249 2.2E-12 T 29-03-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMALA_RS32905 009419ae6f7b74a5c78c00550e7bbad6 250 Gene3D G3DSA:3.30.70.980 84 179 2.4E-29 T 29-03-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMALA_RS10090 1d50a5493defe803d7fdddafefbb3acc 165 SUPERFAMILY SSF55826 12 162 4.71E-43 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 SMALA_RS10090 1d50a5493defe803d7fdddafefbb3acc 165 PIRSF PIRSF006181 7 165 7.3E-53 T 29-03-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC SMALA_RS10090 1d50a5493defe803d7fdddafefbb3acc 165 Pfam PF04073 Aminoacyl-tRNA editing domain 37 153 3.2E-28 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 SMALA_RS10090 1d50a5493defe803d7fdddafefbb3acc 165 Gene3D G3DSA:3.90.960.10 4 165 4.0E-44 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 SMALA_RS10090 1d50a5493defe803d7fdddafefbb3acc 165 TIGRFAM TIGR00011 YbaK_EbsC: Cys-tRNA(Pro) deacylase 12 163 1.4E-55 T 29-03-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC SMALA_RS16965 75ff013eb40f3e28b0dacd3c53ad8a22 328 SUPERFAMILY SSF51735 13 144 1.24E-5 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS16965 75ff013eb40f3e28b0dacd3c53ad8a22 328 PIRSF PIRSF036497 8 324 1.5E-64 T 29-03-2018 IPR022697 Homoserine dehydrogenase lacking ACT domain GO:0004412 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 SMALA_RS16965 75ff013eb40f3e28b0dacd3c53ad8a22 328 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 185 207 - T 29-03-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 SMALA_RS16965 75ff013eb40f3e28b0dacd3c53ad8a22 328 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 17 130 4.7E-5 T 29-03-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 SMALA_RS16965 75ff013eb40f3e28b0dacd3c53ad8a22 328 Gene3D G3DSA:3.40.50.720 7 160 3.7E-10 T 29-03-2018 SMALA_RS16965 75ff013eb40f3e28b0dacd3c53ad8a22 328 Gene3D G3DSA:3.30.360.10 161 300 1.2E-26 T 29-03-2018 SMALA_RS16965 75ff013eb40f3e28b0dacd3c53ad8a22 328 SUPERFAMILY SSF55347 152 300 2.29E-24 T 29-03-2018 SMALA_RS16965 75ff013eb40f3e28b0dacd3c53ad8a22 328 Pfam PF00742 Homoserine dehydrogenase 155 316 5.0E-26 T 29-03-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 SMALA_RS33520 e9751b148758a26ae98ce4373bf50e04 509 PRINTS PR00145 Argininosuccinate lyase family signature 112 134 2.6E-26 T 29-03-2018 SMALA_RS33520 e9751b148758a26ae98ce4373bf50e04 509 PRINTS PR00145 Argininosuccinate lyase family signature 153 173 2.6E-26 T 29-03-2018 SMALA_RS33520 e9751b148758a26ae98ce4373bf50e04 509 PRINTS PR00145 Argininosuccinate lyase family signature 241 265 2.6E-26 T 29-03-2018 SMALA_RS33520 e9751b148758a26ae98ce4373bf50e04 509 PRINTS PR00145 Argininosuccinate lyase family signature 285 301 2.6E-26 T 29-03-2018 SMALA_RS33520 e9751b148758a26ae98ce4373bf50e04 509 PRINTS PR00145 Argininosuccinate lyase family signature 203 219 2.6E-26 T 29-03-2018 SMALA_RS33520 e9751b148758a26ae98ce4373bf50e04 509 PRINTS PR00149 Fumarate lyase superfamily signature 158 176 8.0E-13 T 29-03-2018 IPR000362 Fumarate lyase family SMALA_RS33520 e9751b148758a26ae98ce4373bf50e04 509 PRINTS PR00149 Fumarate lyase superfamily signature 285 301 8.0E-13 T 29-03-2018 IPR000362 Fumarate lyase family SMALA_RS33520 e9751b148758a26ae98ce4373bf50e04 509 PRINTS PR00149 Fumarate lyase superfamily signature 113 131 8.0E-13 T 29-03-2018 IPR000362 Fumarate lyase family SMALA_RS33520 e9751b148758a26ae98ce4373bf50e04 509 PRINTS PR00149 Fumarate lyase superfamily signature 241 268 8.0E-13 T 29-03-2018 IPR000362 Fumarate lyase family SMALA_RS33520 e9751b148758a26ae98ce4373bf50e04 509 Gene3D G3DSA:1.10.275.10 14 117 0.0018 T 29-03-2018 IPR024083 Fumarase/histidase, N-terminal SMALA_RS33520 e9751b148758a26ae98ce4373bf50e04 509 Pfam PF00206 Lyase 69 301 7.4E-28 T 29-03-2018 IPR022761 Fumarate lyase, N-terminal SMALA_RS33520 e9751b148758a26ae98ce4373bf50e04 509 Gene3D G3DSA:1.20.200.10 118 428 8.0E-61 T 29-03-2018 SMALA_RS33520 e9751b148758a26ae98ce4373bf50e04 509 SUPERFAMILY SSF48557 39 467 2.2E-68 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 SMALA_RS41730 c3764da5b8f3fb6bb7035f01e15f3724 358 SUPERFAMILY SSF50331 250 350 1.56E-10 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal SMALA_RS41730 c3764da5b8f3fb6bb7035f01e15f3724 358 Gene3D G3DSA:2.40.50.140 286 346 2.4E-6 T 29-03-2018 SMALA_RS41730 c3764da5b8f3fb6bb7035f01e15f3724 358 Gene3D G3DSA:3.40.50.300 13 263 1.5E-76 T 29-03-2018 SMALA_RS41730 c3764da5b8f3fb6bb7035f01e15f3724 358 SMART SM00382 41 224 1.1E-20 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS41730 c3764da5b8f3fb6bb7035f01e15f3724 358 Pfam PF08402 TOBE domain 283 349 2.0E-11 T 29-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 SMALA_RS41730 c3764da5b8f3fb6bb7035f01e15f3724 358 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS41730 c3764da5b8f3fb6bb7035f01e15f3724 358 SUPERFAMILY SSF52540 17 253 1.56E-87 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS41730 c3764da5b8f3fb6bb7035f01e15f3724 358 Pfam PF00005 ABC transporter 32 174 1.6E-34 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS08465 b622f03fa21930ea6f8fe1ee6502e481 439 Pfam PF13535 ATP-grasp domain 184 322 7.4E-9 T 29-03-2018 SMALA_RS08465 b622f03fa21930ea6f8fe1ee6502e481 439 Gene3D G3DSA:3.30.470.20 149 432 1.4E-27 T 29-03-2018 SMALA_RS08465 b622f03fa21930ea6f8fe1ee6502e481 439 Gene3D G3DSA:3.40.50.20 45 148 8.4E-9 T 29-03-2018 SMALA_RS08465 b622f03fa21930ea6f8fe1ee6502e481 439 SUPERFAMILY SSF56059 123 349 5.58E-30 T 29-03-2018 SMALA_RS40680 dca6787ed8c775b2f41e0d5ed7ab6bae 306 Gene3D G3DSA:3.10.180.10 1 108 6.0E-7 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS40680 dca6787ed8c775b2f41e0d5ed7ab6bae 306 SUPERFAMILY SSF54593 3 88 1.69E-8 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS40680 dca6787ed8c775b2f41e0d5ed7ab6bae 306 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 144 254 1.4E-9 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMALA_RS40680 dca6787ed8c775b2f41e0d5ed7ab6bae 306 SUPERFAMILY SSF54593 139 284 1.51E-29 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS40680 dca6787ed8c775b2f41e0d5ed7ab6bae 306 Gene3D G3DSA:3.10.180.10 133 289 2.5E-23 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS18630 c0a369e604813a46f2fe3ef163241c77 289 Hamap MF_00942 Endonuclease III [nth]. 35 248 38.191 T 29-03-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 SMALA_RS18630 c0a369e604813a46f2fe3ef163241c77 289 SUPERFAMILY SSF48150 44 254 7.22E-69 T 29-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 SMALA_RS18630 c0a369e604813a46f2fe3ef163241c77 289 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 73 207 1.1E-21 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 SMALA_RS18630 c0a369e604813a46f2fe3ef163241c77 289 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 226 242 - T 29-03-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 SMALA_RS18630 c0a369e604813a46f2fe3ef163241c77 289 ProSitePatterns PS01155 Endonuclease III family signature. 141 170 - T 29-03-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 SMALA_RS18630 c0a369e604813a46f2fe3ef163241c77 289 Gene3D G3DSA:1.10.340.30 42 162 4.0E-25 T 29-03-2018 SMALA_RS18630 c0a369e604813a46f2fe3ef163241c77 289 Gene3D G3DSA:1.10.1670.10 163 261 2.1E-32 T 29-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 SMALA_RS18630 c0a369e604813a46f2fe3ef163241c77 289 SMART SM00478 77 224 3.5E-60 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 SMALA_RS18630 c0a369e604813a46f2fe3ef163241c77 289 TIGRFAM TIGR01083 nth: endonuclease III 44 233 4.6E-76 T 29-03-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 SMALA_RS18630 c0a369e604813a46f2fe3ef163241c77 289 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 226 242 3.8E-5 T 29-03-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 SMALA_RS18630 c0a369e604813a46f2fe3ef163241c77 289 Pfam PF00633 Helix-hairpin-helix motif 138 165 9.1E-8 T 29-03-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 SMALA_RS18630 c0a369e604813a46f2fe3ef163241c77 289 SMART SM00525 225 245 1.6E-6 T 29-03-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 SMALA_RS27625 9d3a4a0b93665fce76433ece85e78bae 453 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 3 135 1.2E-7 T 29-03-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 SMALA_RS27625 9d3a4a0b93665fce76433ece85e78bae 453 Gene3D G3DSA:3.40.50.2000 278 422 1.3E-33 T 29-03-2018 SMALA_RS27625 9d3a4a0b93665fce76433ece85e78bae 453 SUPERFAMILY SSF53756 161 432 6.09E-79 T 29-03-2018 SMALA_RS27625 9d3a4a0b93665fce76433ece85e78bae 453 SUPERFAMILY SSF53756 1 127 6.09E-79 T 29-03-2018 SMALA_RS27625 9d3a4a0b93665fce76433ece85e78bae 453 Gene3D G3DSA:3.40.50.2000 1 277 1.6E-37 T 29-03-2018 SMALA_RS27625 9d3a4a0b93665fce76433ece85e78bae 453 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 334 407 2.1E-5 T 29-03-2018 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 Reactome: R-HSA-156588 SMALA_RS15210 7f542d13ad93e499168f8f3e5c35f2b0 75 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 19 66 6.9E-12 T 29-03-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 SMALA_RS15210 7f542d13ad93e499168f8f3e5c35f2b0 75 Gene3D G3DSA:1.10.10.10 19 75 5.9E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS15210 7f542d13ad93e499168f8f3e5c35f2b0 75 Pfam PF12728 Helix-turn-helix domain 19 68 2.9E-8 T 29-03-2018 SMALA_RS06005 e943d92236809126b3f1e266f96a16f0 436 TIGRFAM TIGR03082 Gneg_AbrB_dup: membrane protein AbrB duplication 241 397 1.0E-34 T 29-03-2018 IPR017516 AbrB duplication SMALA_RS06005 e943d92236809126b3f1e266f96a16f0 436 TIGRFAM TIGR03082 Gneg_AbrB_dup: membrane protein AbrB duplication 50 206 9.7E-36 T 29-03-2018 IPR017516 AbrB duplication SMALA_RS06005 e943d92236809126b3f1e266f96a16f0 436 Pfam PF05145 Transition state regulatory protein AbrB 93 397 8.9E-73 T 29-03-2018 IPR007820 AbrB family GO:0010468|GO:0016021 SMALA_RS19480 75962a2c2a549dcb3696489a59f17b15 226 SUPERFAMILY SSF52788 6 161 7.2E-47 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily SMALA_RS19480 75962a2c2a549dcb3696489a59f17b15 226 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 85 100 2.7E-20 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 SMALA_RS19480 75962a2c2a549dcb3696489a59f17b15 226 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 52 68 2.7E-20 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 SMALA_RS19480 75962a2c2a549dcb3696489a59f17b15 226 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 133 148 2.7E-20 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 SMALA_RS19480 75962a2c2a549dcb3696489a59f17b15 226 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 9 26 2.7E-20 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 SMALA_RS19480 75962a2c2a549dcb3696489a59f17b15 226 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 9 155 1.8E-43 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily SMALA_RS19480 75962a2c2a549dcb3696489a59f17b15 226 Gene3D G3DSA:3.40.50.2300 3 173 4.8E-52 T 29-03-2018 SMALA_RS19480 75962a2c2a549dcb3696489a59f17b15 226 SMART SM00226 7 161 1.0E-50 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily SMALA_RS40135 6bffbf39877a44bb08828c5beed10f31 267 Gene3D G3DSA:1.10.10.10 43 119 1.6E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS40135 6bffbf39877a44bb08828c5beed10f31 267 SUPERFAMILY SSF46785 60 120 8.74E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS40135 6bffbf39877a44bb08828c5beed10f31 267 Pfam PF00392 Bacterial regulatory proteins, gntR family 60 112 5.5E-15 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS40135 6bffbf39877a44bb08828c5beed10f31 267 Gene3D G3DSA:1.20.120.530 120 267 1.3E-27 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS40135 6bffbf39877a44bb08828c5beed10f31 267 SMART SM00345 59 116 2.9E-13 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS40135 6bffbf39877a44bb08828c5beed10f31 267 SMART SM00895 126 250 4.7E-13 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS40135 6bffbf39877a44bb08828c5beed10f31 267 Pfam PF07729 FCD domain 126 247 7.4E-19 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS40135 6bffbf39877a44bb08828c5beed10f31 267 SUPERFAMILY SSF48008 121 257 3.66E-22 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS42245 da71600afdb90ff778550c940d8522c8 273 Gene3D G3DSA:3.40.50.720 71 244 1.3E-45 T 29-03-2018 SMALA_RS42245 da71600afdb90ff778550c940d8522c8 273 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 3 258 4.1E-11 T 29-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 SMALA_RS42245 da71600afdb90ff778550c940d8522c8 273 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 70 243 3.8E-45 T 29-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 SMALA_RS42245 da71600afdb90ff778550c940d8522c8 273 SUPERFAMILY SSF51735 64 244 1.97E-46 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS42245 da71600afdb90ff778550c940d8522c8 273 Gene3D G3DSA:3.40.50.720 1 70 6.5E-14 T 29-03-2018 SMALA_RS42245 da71600afdb90ff778550c940d8522c8 273 SUPERFAMILY SSF52283 3 93 1.3E-14 T 29-03-2018 SMALA_RS13940 4b16dbcfdbc0cccbdace64ff9ae89f07 747 Gene3D G3DSA:3.40.50.300 295 504 7.8E-36 T 29-03-2018 SMALA_RS13940 4b16dbcfdbc0cccbdace64ff9ae89f07 747 SUPERFAMILY SSF52540 553 719 5.32E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS13940 4b16dbcfdbc0cccbdace64ff9ae89f07 747 SUPERFAMILY SSF52540 446 512 5.32E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS13940 4b16dbcfdbc0cccbdace64ff9ae89f07 747 Pfam PF13538 UvrD-like helicase C-terminal domain 658 706 1.3E-19 T 29-03-2018 IPR027785 UvrD-like helicase C-terminal domain SMALA_RS13940 4b16dbcfdbc0cccbdace64ff9ae89f07 747 TIGRFAM TIGR01448 recD_rel: helicase, RecD/TraA family 8 731 2.8E-200 T 29-03-2018 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 SMALA_RS13940 4b16dbcfdbc0cccbdace64ff9ae89f07 747 Pfam PF14520 Helix-hairpin-helix domain 94 143 1.7E-7 T 29-03-2018 SMALA_RS13940 4b16dbcfdbc0cccbdace64ff9ae89f07 747 Hamap MF_01488 ATP-dependent RecD-like DNA helicase [recD2]. 4 744 29.261 T 29-03-2018 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 SMALA_RS13940 4b16dbcfdbc0cccbdace64ff9ae89f07 747 SUPERFAMILY SSF52540 184 267 1.38E-43 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS13940 4b16dbcfdbc0cccbdace64ff9ae89f07 747 SUPERFAMILY SSF52540 332 483 1.38E-43 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS13940 4b16dbcfdbc0cccbdace64ff9ae89f07 747 Pfam PF13604 AAA domain 336 514 2.8E-44 T 29-03-2018 SMALA_RS13940 4b16dbcfdbc0cccbdace64ff9ae89f07 747 SUPERFAMILY SSF47781 86 162 6.39E-10 T 29-03-2018 IPR010994 RuvA domain 2-like SMALA_RS13940 4b16dbcfdbc0cccbdace64ff9ae89f07 747 Gene3D G3DSA:3.40.50.300 505 719 9.3E-33 T 29-03-2018 SMALA_RS13940 4b16dbcfdbc0cccbdace64ff9ae89f07 747 Gene3D G3DSA:1.10.150.20 93 124 5.6E-5 T 29-03-2018 SMALA_RS13940 4b16dbcfdbc0cccbdace64ff9ae89f07 747 Pfam PF14490 Helix-hairpin-helix containing domain 144 234 7.6E-32 T 29-03-2018 IPR029493 RecD helicase-like helix-hairpin-helix domain SMALA_RS13940 4b16dbcfdbc0cccbdace64ff9ae89f07 747 Gene3D G3DSA:1.10.150.280 125 211 1.8E-6 T 29-03-2018 SMALA_RS38525 f4d0e1cab841e34638e2db01feae1b7f 499 Pfam PF00171 Aldehyde dehydrogenase family 33 493 5.5E-165 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS38525 f4d0e1cab841e34638e2db01feae1b7f 499 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 266 273 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 SMALA_RS38525 f4d0e1cab841e34638e2db01feae1b7f 499 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 294 305 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 SMALA_RS38525 f4d0e1cab841e34638e2db01feae1b7f 499 Gene3D G3DSA:3.40.605.10 14 284 1.2E-96 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS38525 f4d0e1cab841e34638e2db01feae1b7f 499 SUPERFAMILY SSF53720 15 497 1.96E-159 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMALA_RS38525 f4d0e1cab841e34638e2db01feae1b7f 499 Gene3D G3DSA:3.40.309.10 285 480 2.0E-68 T 29-03-2018 SMALA_RS09185 25096969a6a867695576d619a08777d9 716 TIGRFAM TIGR02442 Cob-chelat-sub: cobaltochelatase subunit 5 692 2.4E-251 T 29-03-2018 IPR012804 Cobaltochelatase subunit, putative SMALA_RS09185 25096969a6a867695576d619a08777d9 716 SUPERFAMILY SSF53300 525 691 6.68E-21 T 29-03-2018 IPR002035 von Willebrand factor, type A SMALA_RS09185 25096969a6a867695576d619a08777d9 716 Gene3D G3DSA:3.40.50.410 499 686 3.7E-25 T 29-03-2018 IPR002035 von Willebrand factor, type A SMALA_RS09185 25096969a6a867695576d619a08777d9 716 SMART SM00382 28 205 8.8E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS09185 25096969a6a867695576d619a08777d9 716 Gene3D G3DSA:1.10.8.80 247 335 1.1E-21 T 29-03-2018 SMALA_RS09185 25096969a6a867695576d619a08777d9 716 SUPERFAMILY SSF52540 5 329 1.15E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS09185 25096969a6a867695576d619a08777d9 716 SMART SM00327 522 704 7.4E-23 T 29-03-2018 IPR002035 von Willebrand factor, type A SMALA_RS09185 25096969a6a867695576d619a08777d9 716 Pfam PF01078 Magnesium chelatase, subunit ChlI 113 182 1.9E-7 T 29-03-2018 IPR000523 Magnesium chelatase ChlI domain SMALA_RS09185 25096969a6a867695576d619a08777d9 716 Gene3D G3DSA:3.40.50.300 2 202 7.5E-23 T 29-03-2018 SMALA_RS09185 25096969a6a867695576d619a08777d9 716 Pfam PF13519 von Willebrand factor type A domain 525 631 3.0E-16 T 29-03-2018 IPR002035 von Willebrand factor, type A SMALA_RS07025 c2b550a9eb7206b42407903e7ff283e6 253 Pfam PF08220 DeoR-like helix-turn-helix domain 6 58 1.7E-16 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMALA_RS07025 c2b550a9eb7206b42407903e7ff283e6 253 SUPERFAMILY SSF46785 6 71 1.23E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS07025 c2b550a9eb7206b42407903e7ff283e6 253 Gene3D G3DSA:3.40.50.1360 67 242 4.3E-33 T 29-03-2018 SMALA_RS07025 c2b550a9eb7206b42407903e7ff283e6 253 SUPERFAMILY SSF100950 75 233 2.3E-24 T 29-03-2018 SMALA_RS07025 c2b550a9eb7206b42407903e7ff283e6 253 Pfam PF00455 DeoR C terminal sensor domain 76 232 2.9E-37 T 29-03-2018 IPR014036 DeoR C-terminal sensor domain SMALA_RS07025 c2b550a9eb7206b42407903e7ff283e6 253 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 29-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 SMALA_RS07025 c2b550a9eb7206b42407903e7ff283e6 253 Gene3D G3DSA:1.10.10.10 1 62 5.1E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS07025 c2b550a9eb7206b42407903e7ff283e6 253 SMART SM00420 6 58 4.9E-18 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMALA_RS07025 c2b550a9eb7206b42407903e7ff283e6 253 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 6.2E-7 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMALA_RS07025 c2b550a9eb7206b42407903e7ff283e6 253 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 6.2E-7 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMALA_RS07025 c2b550a9eb7206b42407903e7ff283e6 253 SMART SM01134 73 234 3.6E-54 T 29-03-2018 SMALA_RS02275 a213e6761a099b1dc5343cf7631f2cd3 231 Gene3D G3DSA:3.40.50.1000 13 211 4.5E-37 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS02275 a213e6761a099b1dc5343cf7631f2cd3 231 SUPERFAMILY SSF56784 19 225 1.76E-53 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS02275 a213e6761a099b1dc5343cf7631f2cd3 231 TIGRFAM TIGR01454 AHBA_synth_RP: AHBA synthesis associated protein 23 226 5.7E-107 T 29-03-2018 IPR006351 3-amino-5-hydroxybenzoic acid synthesis-related SMALA_RS02275 a213e6761a099b1dc5343cf7631f2cd3 231 Pfam PF13419 Haloacid dehalogenase-like hydrolase 23 195 5.4E-33 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS02275 a213e6761a099b1dc5343cf7631f2cd3 231 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 109 122 1.2E-7 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMALA_RS02275 a213e6761a099b1dc5343cf7631f2cd3 231 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 140 156 1.2E-7 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMALA_RS02275 a213e6761a099b1dc5343cf7631f2cd3 231 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 20 31 1.2E-7 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMALA_RS02275 a213e6761a099b1dc5343cf7631f2cd3 231 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 158 178 1.2E-7 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMALA_RS02275 a213e6761a099b1dc5343cf7631f2cd3 231 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 102 190 1.1E-8 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMALA_RS02275 a213e6761a099b1dc5343cf7631f2cd3 231 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 132 194 4.4E-8 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMALA_RS42920 310cc7975cacc1c63347ddba88191e26 3811 SUPERFAMILY SSF47336 974 1045 2.88E-16 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS42920 310cc7975cacc1c63347ddba88191e26 3811 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2078 2089 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS42920 310cc7975cacc1c63347ddba88191e26 3811 ProSitePatterns PS00455 Putative AMP-binding domain signature. 3120 3131 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS42920 310cc7975cacc1c63347ddba88191e26 3811 SUPERFAMILY SSF52777 193 425 1.22E-34 T 29-03-2018 SMALA_RS42920 310cc7975cacc1c63347ddba88191e26 3811 Gene3D G3DSA:3.40.50.980 1934 2083 6.9E-45 T 29-03-2018 SMALA_RS42920 310cc7975cacc1c63347ddba88191e26 3811 Gene3D G3DSA:3.40.50.1820 3551 3808 7.6E-25 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS42920 310cc7975cacc1c63347ddba88191e26 3811 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2472 2487 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS42920 310cc7975cacc1c63347ddba88191e26 3811 Gene3D G3DSA:1.10.1200.10 2454 2516 2.5E-22 T 29-03-2018 SMALA_RS42920 310cc7975cacc1c63347ddba88191e26 3811 SMART SM00823 Phosphopantetheine attachment site 980 1048 2.8E-6 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS42920 310cc7975cacc1c63347ddba88191e26 3811 SMART SM00823 Phosphopantetheine attachment site 2448 2517 3.3E-8 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS42920 310cc7975cacc1c63347ddba88191e26 3811 SMART SM00823 Phosphopantetheine attachment site 3477 3546 9.6E-5 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS42920 310cc7975cacc1c63347ddba88191e26 3811 SUPERFAMILY SSF56801 2955 3490 2.75E-137 T 29-03-2018 SMALA_RS42920 310cc7975cacc1c63347ddba88191e26 3811 SUPERFAMILY SSF47336 3471 3543 2.62E-16 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS42920 310cc7975cacc1c63347ddba88191e26 3811 SUPERFAMILY SSF52777 10 174 4.78E-23 T 29-03-2018 SMALA_RS42920 310cc7975cacc1c63347ddba88191e26 3811 SUPERFAMILY SSF52777 1246 1496 2.78E-26 T 29-03-2018 SMALA_RS42920 310cc7975cacc1c63347ddba88191e26 3811 SUPERFAMILY SSF56801 1934 2461 5.1E-147 T 29-03-2018 SMALA_RS42920 310cc7975cacc1c63347ddba88191e26 3811 SUPERFAMILY SSF52777 1066 1216 4.45E-21 T 29-03-2018 SMALA_RS42920 310cc7975cacc1c63347ddba88191e26 3811 Gene3D G3DSA:2.30.38.10 2246 2325 8.8E-24 T 29-03-2018 SMALA_RS42920 310cc7975cacc1c63347ddba88191e26 3811 Gene3D G3DSA:2.30.38.10 776 857 2.0E-22 T 29-03-2018 SMALA_RS42920 310cc7975cacc1c63347ddba88191e26 3811 Gene3D G3DSA:2.30.38.10 3285 3361 4.5E-24 T 29-03-2018 SMALA_RS42920 310cc7975cacc1c63347ddba88191e26 3811 SUPERFAMILY SSF52777 2532 2725 4.11E-45 T 29-03-2018 SMALA_RS42920 310cc7975cacc1c63347ddba88191e26 3811 SUPERFAMILY SSF52777 2712 2964 7.0E-57 T 29-03-2018 SMALA_RS42920 310cc7975cacc1c63347ddba88191e26 3811 Gene3D G3DSA:1.10.1200.10 3464 3550 2.3E-20 T 29-03-2018 SMALA_RS42920 310cc7975cacc1c63347ddba88191e26 3811 SUPERFAMILY SSF56801 455 993 6.41E-131 T 29-03-2018 SMALA_RS42920 310cc7975cacc1c63347ddba88191e26 3811 Gene3D G3DSA:3.40.50.980 459 615 4.4E-38 T 29-03-2018 SMALA_RS42920 310cc7975cacc1c63347ddba88191e26 3811 SUPERFAMILY SSF47336 2443 2513 1.7E-19 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS42920 310cc7975cacc1c63347ddba88191e26 3811 Pfam PF13193 AMP-binding enzyme C-terminal domain 875 951 4.0E-12 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS42920 310cc7975cacc1c63347ddba88191e26 3811 Pfam PF13193 AMP-binding enzyme C-terminal domain 3380 3452 5.5E-9 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS42920 310cc7975cacc1c63347ddba88191e26 3811 Pfam PF13193 AMP-binding enzyme C-terminal domain 2343 2424 3.5E-12 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS42920 310cc7975cacc1c63347ddba88191e26 3811 Gene3D G3DSA:3.40.50.980 616 765 1.1E-34 T 29-03-2018 SMALA_RS42920 310cc7975cacc1c63347ddba88191e26 3811 Gene3D G3DSA:3.40.50.980 2987 3116 3.0E-25 T 29-03-2018 SMALA_RS42920 310cc7975cacc1c63347ddba88191e26 3811 SUPERFAMILY SSF52777 1499 1683 1.56E-42 T 29-03-2018 SMALA_RS42920 310cc7975cacc1c63347ddba88191e26 3811 Gene3D G3DSA:3.30.559.10 1498 1687 1.7E-39 T 29-03-2018 SMALA_RS42920 310cc7975cacc1c63347ddba88191e26 3811 Gene3D G3DSA:3.30.559.10 1049 1241 3.0E-14 T 29-03-2018 SMALA_RS42920 310cc7975cacc1c63347ddba88191e26 3811 Gene3D G3DSA:3.30.300.30 2330 2453 2.4E-33 T 29-03-2018 SMALA_RS42920 310cc7975cacc1c63347ddba88191e26 3811 Gene3D G3DSA:3.30.300.30 862 983 4.0E-33 T 29-03-2018 SMALA_RS42920 310cc7975cacc1c63347ddba88191e26 3811 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1004 1019 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS42920 310cc7975cacc1c63347ddba88191e26 3811 Gene3D G3DSA:3.30.300.30 3366 3463 3.3E-29 T 29-03-2018 SMALA_RS42920 310cc7975cacc1c63347ddba88191e26 3811 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3501 3516 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS42920 310cc7975cacc1c63347ddba88191e26 3811 Pfam PF00668 Condensation domain 1500 1921 1.8E-76 T 29-03-2018 IPR001242 Condensation domain SMALA_RS42920 310cc7975cacc1c63347ddba88191e26 3811 Pfam PF00668 Condensation domain 2536 2975 6.1E-81 T 29-03-2018 IPR001242 Condensation domain SMALA_RS42920 310cc7975cacc1c63347ddba88191e26 3811 Pfam PF00668 Condensation domain 6 445 7.5E-38 T 29-03-2018 IPR001242 Condensation domain SMALA_RS42920 310cc7975cacc1c63347ddba88191e26 3811 Pfam PF00668 Condensation domain 1168 1343 1.4E-19 T 29-03-2018 IPR001242 Condensation domain SMALA_RS42920 310cc7975cacc1c63347ddba88191e26 3811 Pfam PF00550 Phosphopantetheine attachment site 2450 2513 7.9E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS42920 310cc7975cacc1c63347ddba88191e26 3811 Pfam PF00550 Phosphopantetheine attachment site 983 1043 2.5E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS42920 310cc7975cacc1c63347ddba88191e26 3811 Pfam PF00550 Phosphopantetheine attachment site 3481 3542 5.9E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS42920 310cc7975cacc1c63347ddba88191e26 3811 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1963 2359 2.4E-132 T 29-03-2018 IPR010071 Amino acid adenylation domain SMALA_RS42920 310cc7975cacc1c63347ddba88191e26 3811 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 3016 3396 2.8E-115 T 29-03-2018 IPR010071 Amino acid adenylation domain SMALA_RS42920 310cc7975cacc1c63347ddba88191e26 3811 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 489 890 2.1E-117 T 29-03-2018 IPR010071 Amino acid adenylation domain SMALA_RS42920 310cc7975cacc1c63347ddba88191e26 3811 SUPERFAMILY SSF52777 1670 1913 1.06E-53 T 29-03-2018 SMALA_RS42920 310cc7975cacc1c63347ddba88191e26 3811 Pfam PF00501 AMP-binding enzyme 2997 3372 1.9E-86 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS42920 310cc7975cacc1c63347ddba88191e26 3811 Pfam PF00501 AMP-binding enzyme 1942 2335 9.8E-100 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS42920 310cc7975cacc1c63347ddba88191e26 3811 Pfam PF00501 AMP-binding enzyme 466 867 5.5E-85 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS42920 310cc7975cacc1c63347ddba88191e26 3811 Gene3D G3DSA:3.30.559.10 1 192 9.3E-21 T 29-03-2018 SMALA_RS42920 310cc7975cacc1c63347ddba88191e26 3811 Gene3D G3DSA:3.30.559.10 2517 2710 5.2E-42 T 29-03-2018 SMALA_RS42920 310cc7975cacc1c63347ddba88191e26 3811 SUPERFAMILY SSF53474 3543 3807 3.33E-52 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS42920 310cc7975cacc1c63347ddba88191e26 3811 ProSitePatterns PS00455 Putative AMP-binding domain signature. 613 624 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS42920 310cc7975cacc1c63347ddba88191e26 3811 Gene3D G3DSA:3.40.50.980 3117 3284 4.2E-48 T 29-03-2018 SMALA_RS42920 310cc7975cacc1c63347ddba88191e26 3811 Gene3D G3DSA:3.40.50.980 2084 2245 9.2E-40 T 29-03-2018 SMALA_RS42920 310cc7975cacc1c63347ddba88191e26 3811 Gene3D G3DSA:1.10.1200.10 984 1048 3.1E-20 T 29-03-2018 SMALA_RS42920 310cc7975cacc1c63347ddba88191e26 3811 Pfam PF00975 Thioesterase domain 3565 3796 2.8E-23 T 29-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 SMALA_RS13465 3f5e11caccd9890f08719b2661ddafb1 441 Gene3D G3DSA:1.20.1170.10 20 423 7.8E-7 T 29-03-2018 SMALA_RS36450 5ac532f77a1a90bc412b4064414f5ca7 164 Gene3D G3DSA:1.10.10.10 3 54 8.2E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS36450 5ac532f77a1a90bc412b4064414f5ca7 164 SMART SM00344 3 112 3.4E-31 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 SMALA_RS36450 5ac532f77a1a90bc412b4064414f5ca7 164 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 1.9E-14 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMALA_RS36450 5ac532f77a1a90bc412b4064414f5ca7 164 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 30 1.9E-14 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMALA_RS36450 5ac532f77a1a90bc412b4064414f5ca7 164 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 1.9E-14 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMALA_RS36450 5ac532f77a1a90bc412b4064414f5ca7 164 SUPERFAMILY SSF46785 2 62 1.48E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS36450 5ac532f77a1a90bc412b4064414f5ca7 164 ProSitePatterns PS00519 AsnC-type HTH domain signature. 21 47 - T 29-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site SMALA_RS36450 5ac532f77a1a90bc412b4064414f5ca7 164 Pfam PF13412 Winged helix-turn-helix DNA-binding 3 49 5.3E-14 T 29-03-2018 SMALA_RS36450 5ac532f77a1a90bc412b4064414f5ca7 164 SUPERFAMILY SSF54909 64 144 4.29E-12 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel SMALA_RS36450 5ac532f77a1a90bc412b4064414f5ca7 164 Gene3D G3DSA:3.30.70.920 55 140 1.4E-16 T 29-03-2018 SMALA_RS36450 5ac532f77a1a90bc412b4064414f5ca7 164 Pfam PF01037 Lrp/AsnC ligand binding domain 70 142 1.6E-11 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain SMALA_RS28605 bfdc687863c79c776ffa69a83a270975 1371 SMART SM00382 1158 1348 0.23 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS28605 bfdc687863c79c776ffa69a83a270975 1371 SMART SM00382 832 1008 0.29 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS28605 bfdc687863c79c776ffa69a83a270975 1371 SMART SM00382 476 655 0.12 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS28605 bfdc687863c79c776ffa69a83a270975 1371 Gene3D G3DSA:3.40.50.300 1113 1320 1.1E-7 T 29-03-2018 SMALA_RS28605 bfdc687863c79c776ffa69a83a270975 1371 Gene3D G3DSA:3.40.50.300 392 661 5.5E-19 T 29-03-2018 SMALA_RS28605 bfdc687863c79c776ffa69a83a270975 1371 Gene3D G3DSA:3.40.50.300 805 1021 1.7E-12 T 29-03-2018 SMALA_RS28605 bfdc687863c79c776ffa69a83a270975 1371 SUPERFAMILY SSF52540 786 1026 4.3E-23 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS28605 bfdc687863c79c776ffa69a83a270975 1371 TIGRFAM TIGR03924 T7SS_EccC_a: type VII secretion protein EccCa 25 699 7.4E-251 T 29-03-2018 IPR023836 EccCa-like, Actinobacteria SMALA_RS28605 bfdc687863c79c776ffa69a83a270975 1371 Pfam PF01580 FtsK/SpoIIIE family 440 567 5.1E-24 T 29-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 SMALA_RS28605 bfdc687863c79c776ffa69a83a270975 1371 Pfam PF01580 FtsK/SpoIIIE family 817 1045 3.2E-53 T 29-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 SMALA_RS28605 bfdc687863c79c776ffa69a83a270975 1371 Pfam PF01580 FtsK/SpoIIIE family 579 633 1.2E-5 T 29-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 SMALA_RS28605 bfdc687863c79c776ffa69a83a270975 1371 TIGRFAM TIGR03925 T7SS_EccC_b: type VII secretion protein EccCb 751 1053 2.0E-127 T 29-03-2018 IPR023837 EccCb-like, Actinobacteria SMALA_RS28605 bfdc687863c79c776ffa69a83a270975 1371 SUPERFAMILY SSF52540 1118 1299 2.75E-13 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS28605 bfdc687863c79c776ffa69a83a270975 1371 SUPERFAMILY SSF52540 441 700 1.95E-32 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS25125 b732237acaf3eca849e0d1ea2fa16241 363 Gene3D G3DSA:3.20.20.120 130 363 6.5E-55 T 29-03-2018 IPR029065 Enolase C-terminal domain-like SMALA_RS25125 b732237acaf3eca849e0d1ea2fa16241 363 Gene3D G3DSA:3.30.390.10 1 129 4.0E-32 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMALA_RS25125 b732237acaf3eca849e0d1ea2fa16241 363 SUPERFAMILY SSF54826 4 129 2.8E-29 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMALA_RS25125 b732237acaf3eca849e0d1ea2fa16241 363 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 8 128 4.8E-19 T 29-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain SMALA_RS25125 b732237acaf3eca849e0d1ea2fa16241 363 SUPERFAMILY SSF51604 116 361 3.93E-64 T 29-03-2018 IPR029065 Enolase C-terminal domain-like SMALA_RS25125 b732237acaf3eca849e0d1ea2fa16241 363 SMART SM00922 147 243 2.0E-19 T 29-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal SMALA_RS25125 b732237acaf3eca849e0d1ea2fa16241 363 Pfam PF13378 Enolase C-terminal domain-like 151 354 1.3E-56 T 29-03-2018 IPR029065 Enolase C-terminal domain-like SMALA_RS18935 6e76ac55132ad94ab4a8438c7dff1f85 258 Pfam PF00005 ABC transporter 39 184 4.0E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS18935 6e76ac55132ad94ab4a8438c7dff1f85 258 Gene3D G3DSA:3.40.50.300 19 249 3.1E-59 T 29-03-2018 SMALA_RS18935 6e76ac55132ad94ab4a8438c7dff1f85 258 SMART SM00382 48 242 1.4E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS18935 6e76ac55132ad94ab4a8438c7dff1f85 258 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS18935 6e76ac55132ad94ab4a8438c7dff1f85 258 SUPERFAMILY SSF52540 23 241 1.03E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS20410 e6da8dffb008deb40ba4310718f5b0e2 135 SUPERFAMILY SSF55811 2 114 4.2E-23 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMALA_RS20410 e6da8dffb008deb40ba4310718f5b0e2 135 Gene3D G3DSA:3.90.79.10 1 125 2.6E-20 T 29-03-2018 SMALA_RS20410 e6da8dffb008deb40ba4310718f5b0e2 135 Pfam PF00293 NUDIX domain 2 108 9.5E-15 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SMALA_RS32045 e757f864187644826ae025b019f749a8 604 Pfam PF01066 CDP-alcohol phosphatidyltransferase 197 263 1.9E-9 T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 SMALA_RS32045 e757f864187644826ae025b019f749a8 604 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 241 263 - T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 SMALA_RS32045 e757f864187644826ae025b019f749a8 604 Gene3D G3DSA:3.40.190.10 134 221 3.2E-4 T 29-03-2018 SMALA_RS34865 f35c69b5f72082802fdf15b27d88a408 341 Hamap MF_01976 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase [pfp]. 1 341 43.182 T 29-03-2018 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 SMALA_RS34865 f35c69b5f72082802fdf15b27d88a408 341 ProSitePatterns PS00433 Phosphofructokinase signature. 266 284 - T 29-03-2018 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMALA_RS34865 f35c69b5f72082802fdf15b27d88a408 341 SUPERFAMILY SSF53784 1 333 1.09E-118 T 29-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMALA_RS34865 f35c69b5f72082802fdf15b27d88a408 341 Gene3D G3DSA:3.40.50.450 1 206 9.7E-77 T 29-03-2018 SMALA_RS34865 f35c69b5f72082802fdf15b27d88a408 341 PIRSF PIRSF000532 1 339 5.8E-117 T 29-03-2018 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 SMALA_RS34865 f35c69b5f72082802fdf15b27d88a408 341 TIGRFAM TIGR02483 PFK_mixed: phosphofructokinase 2 322 1.7E-146 T 29-03-2018 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 SMALA_RS34865 f35c69b5f72082802fdf15b27d88a408 341 Pfam PF00365 Phosphofructokinase 2 297 1.7E-104 T 29-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMALA_RS34865 f35c69b5f72082802fdf15b27d88a408 341 Gene3D G3DSA:3.40.50.450 207 332 1.3E-8 T 29-03-2018 SMALA_RS34865 f35c69b5f72082802fdf15b27d88a408 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 262 284 6.9E-76 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMALA_RS34865 f35c69b5f72082802fdf15b27d88a408 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 176 193 6.9E-76 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMALA_RS34865 f35c69b5f72082802fdf15b27d88a408 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 31 44 6.9E-76 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMALA_RS34865 f35c69b5f72082802fdf15b27d88a408 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 212 224 6.9E-76 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMALA_RS34865 f35c69b5f72082802fdf15b27d88a408 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 120 137 6.9E-76 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMALA_RS34865 f35c69b5f72082802fdf15b27d88a408 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 138 156 6.9E-76 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMALA_RS34865 f35c69b5f72082802fdf15b27d88a408 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 158 174 6.9E-76 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMALA_RS34865 f35c69b5f72082802fdf15b27d88a408 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 93 109 6.9E-76 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMALA_RS34865 f35c69b5f72082802fdf15b27d88a408 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 5 24 6.9E-76 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMALA_RS09625 c4e8109916fa9dd1f955ab34993b62ab 1008 Gene3D G3DSA:3.40.50.300 613 952 2.0E-55 T 29-03-2018 SMALA_RS09625 c4e8109916fa9dd1f955ab34993b62ab 1008 ProSitePatterns PS00211 ABC transporters family signature. 492 506 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS09625 c4e8109916fa9dd1f955ab34993b62ab 1008 SUPERFAMILY SSF52540 618 913 7.32E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS09625 c4e8109916fa9dd1f955ab34993b62ab 1008 Pfam PF00005 ABC transporter 628 864 1.3E-9 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS09625 c4e8109916fa9dd1f955ab34993b62ab 1008 SUPERFAMILY SSF52540 435 574 9.87E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS09625 c4e8109916fa9dd1f955ab34993b62ab 1008 SUPERFAMILY SSF52540 10 205 9.87E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS09625 c4e8109916fa9dd1f955ab34993b62ab 1008 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 5 929 0.0 T 29-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 SMALA_RS09625 c4e8109916fa9dd1f955ab34993b62ab 1008 Hamap MF_00205 UvrABC system protein A [uvrA]. 2 944 22.776 T 29-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 SMALA_RS09625 c4e8109916fa9dd1f955ab34993b62ab 1008 Gene3D G3DSA:3.40.50.300 37 76 0.006 T 29-03-2018 SMALA_RS09625 c4e8109916fa9dd1f955ab34993b62ab 1008 Gene3D G3DSA:1.20.1580.10 92 492 4.2E-97 T 29-03-2018 SMALA_RS09625 c4e8109916fa9dd1f955ab34993b62ab 1008 Gene3D G3DSA:3.40.50.300 9 36 0.022 T 29-03-2018 SMALA_RS09625 c4e8109916fa9dd1f955ab34993b62ab 1008 ProSitePatterns PS00211 ABC transporters family signature. 834 848 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS32340 6ea4d6df39ccb68fd33832821a05e3c8 416 SUPERFAMILY SSF51556 54 364 7.78E-76 T 29-03-2018 IPR032466 Metal-dependent hydrolase SMALA_RS32340 6ea4d6df39ccb68fd33832821a05e3c8 416 Gene3D G3DSA:3.20.20.140 69 360 5.8E-47 T 29-03-2018 SMALA_RS32340 6ea4d6df39ccb68fd33832821a05e3c8 416 SUPERFAMILY SSF51338 17 54 1.84E-12 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS32340 6ea4d6df39ccb68fd33832821a05e3c8 416 SUPERFAMILY SSF51338 364 399 1.84E-12 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS32340 6ea4d6df39ccb68fd33832821a05e3c8 416 Gene3D G3DSA:2.30.40.10 1 68 3.7E-13 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS32340 6ea4d6df39ccb68fd33832821a05e3c8 416 Pfam PF01979 Amidohydrolase family 50 400 8.8E-34 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 SMALA_RS04930 fbe727a84f3b8549ecd2f889a4550ae3 282 SUPERFAMILY SSF52540 29 250 8.26E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS04930 fbe727a84f3b8549ecd2f889a4550ae3 282 Pfam PF00005 ABC transporter 44 193 1.6E-34 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS04930 fbe727a84f3b8549ecd2f889a4550ae3 282 ProSitePatterns PS00211 ABC transporters family signature. 165 179 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS04930 fbe727a84f3b8549ecd2f889a4550ae3 282 SMART SM00382 53 237 1.8E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS04930 fbe727a84f3b8549ecd2f889a4550ae3 282 Gene3D G3DSA:3.40.50.300 10 261 3.5E-61 T 29-03-2018 SMALA_RS05805 f8f7d7c824d55ed412ce419ad374760c 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 17 34 1.2E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS05805 f8f7d7c824d55ed412ce419ad374760c 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 218 238 1.2E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS05805 f8f7d7c824d55ed412ce419ad374760c 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 1.2E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS05805 f8f7d7c824d55ed412ce419ad374760c 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 1.2E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS05805 f8f7d7c824d55ed412ce419ad374760c 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 1.2E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS05805 f8f7d7c824d55ed412ce419ad374760c 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 1.2E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS05805 f8f7d7c824d55ed412ce419ad374760c 258 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMALA_RS05805 f8f7d7c824d55ed412ce419ad374760c 258 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 24 253 2.9E-52 T 29-03-2018 SMALA_RS05805 f8f7d7c824d55ed412ce419ad374760c 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 2.3E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS05805 f8f7d7c824d55ed412ce419ad374760c 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 2.3E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS05805 f8f7d7c824d55ed412ce419ad374760c 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 2.3E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS05805 f8f7d7c824d55ed412ce419ad374760c 258 Gene3D G3DSA:3.40.50.720 3 256 3.5E-67 T 29-03-2018 SMALA_RS05805 f8f7d7c824d55ed412ce419ad374760c 258 SUPERFAMILY SSF51735 15 253 2.4E-71 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS19570 18224c390210bbd9753f09dc7a19a902 148 SUPERFAMILY SSF55653 58 147 3.53E-25 T 29-03-2018 IPR020069 Ribosomal protein L9, C-terminal SMALA_RS19570 18224c390210bbd9753f09dc7a19a902 148 SUPERFAMILY SSF55658 1 56 2.09E-17 T 29-03-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal SMALA_RS19570 18224c390210bbd9753f09dc7a19a902 148 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 29-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS19570 18224c390210bbd9753f09dc7a19a902 148 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 146 5.6E-40 T 29-03-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS19570 18224c390210bbd9753f09dc7a19a902 148 Gene3D G3DSA:3.10.430.100 63 147 1.4E-29 T 29-03-2018 IPR020069 Ribosomal protein L9, C-terminal SMALA_RS19570 18224c390210bbd9753f09dc7a19a902 148 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 148 26.19 T 29-03-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS19570 18224c390210bbd9753f09dc7a19a902 148 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 45 2.2E-21 T 29-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS19570 18224c390210bbd9753f09dc7a19a902 148 Gene3D G3DSA:3.40.5.10 1 49 3.3E-21 T 29-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS19570 18224c390210bbd9753f09dc7a19a902 148 Pfam PF03948 Ribosomal protein L9, C-terminal domain 63 146 1.4E-28 T 29-03-2018 IPR020069 Ribosomal protein L9, C-terminal SMALA_RS19275 ed914524779bbfc235903eb643767548 491 Pfam PF00392 Bacterial regulatory proteins, gntR family 30 89 1.8E-17 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS19275 ed914524779bbfc235903eb643767548 491 SMART SM00345 30 89 7.8E-18 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS19275 ed914524779bbfc235903eb643767548 491 SUPERFAMILY SSF46785 22 103 3.23E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS19275 ed914524779bbfc235903eb643767548 491 Gene3D G3DSA:3.40.640.10 142 370 7.0E-36 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS19275 ed914524779bbfc235903eb643767548 491 Pfam PF00155 Aminotransferase class I and II 146 424 1.1E-13 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMALA_RS19275 ed914524779bbfc235903eb643767548 491 SUPERFAMILY SSF53383 120 484 5.51E-70 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS19275 ed914524779bbfc235903eb643767548 491 Gene3D G3DSA:1.10.10.10 16 91 1.7E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS19275 ed914524779bbfc235903eb643767548 491 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 49 63 3.7E-5 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS19275 ed914524779bbfc235903eb643767548 491 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 63 79 3.7E-5 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS19275 ed914524779bbfc235903eb643767548 491 Gene3D G3DSA:3.90.1150.10 371 488 2.2E-22 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS04745 e12877eb9fb4e53bd035044e5d50283f 137 Gene3D G3DSA:2.60.120.10 4 136 2.2E-26 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SMALA_RS04745 e12877eb9fb4e53bd035044e5d50283f 137 SUPERFAMILY SSF51182 7 131 7.71E-25 T 29-03-2018 IPR011051 RmlC-like cupin domain SMALA_RS04745 e12877eb9fb4e53bd035044e5d50283f 137 Pfam PF07883 Cupin domain 39 97 1.6E-9 T 29-03-2018 IPR013096 Cupin 2, conserved barrel SMALA_RS12275 29369530540ec8a46ac56561d515e9ab 805 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 88 487 1.9E-112 T 29-03-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 SMALA_RS12275 29369530540ec8a46ac56561d515e9ab 805 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 549 789 1.5E-63 T 29-03-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 SMALA_RS12275 29369530540ec8a46ac56561d515e9ab 805 PRINTS PR01755 Bacterial translocase SecF protein signature 705 723 1.2E-21 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial SMALA_RS12275 29369530540ec8a46ac56561d515e9ab 805 PRINTS PR01755 Bacterial translocase SecF protein signature 657 671 1.2E-21 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial SMALA_RS12275 29369530540ec8a46ac56561d515e9ab 805 PRINTS PR01755 Bacterial translocase SecF protein signature 548 563 1.2E-21 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial SMALA_RS12275 29369530540ec8a46ac56561d515e9ab 805 PRINTS PR01755 Bacterial translocase SecF protein signature 737 752 1.2E-21 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial SMALA_RS12275 29369530540ec8a46ac56561d515e9ab 805 SUPERFAMILY SSF82866 631 798 2.62E-30 T 29-03-2018 SMALA_RS12275 29369530540ec8a46ac56561d515e9ab 805 Gene3D G3DSA:1.20.1640.10 586 805 7.4E-26 T 29-03-2018 SMALA_RS12275 29369530540ec8a46ac56561d515e9ab 805 Pfam PF02355 Protein export membrane protein 615 797 5.0E-61 T 29-03-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial SMALA_RS12275 29369530540ec8a46ac56561d515e9ab 805 Pfam PF02355 Protein export membrane protein 320 488 5.1E-13 T 29-03-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial SMALA_RS12275 29369530540ec8a46ac56561d515e9ab 805 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 60 502 35.654 T 29-03-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 SMALA_RS12275 29369530540ec8a46ac56561d515e9ab 805 Gene3D G3DSA:1.20.1640.10 289 494 1.5E-28 T 29-03-2018 SMALA_RS12275 29369530540ec8a46ac56561d515e9ab 805 Pfam PF07549 SecD/SecF GG Motif 82 102 1.8E-4 T 29-03-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site SMALA_RS12275 29369530540ec8a46ac56561d515e9ab 805 Pfam PF07549 SecD/SecF GG Motif 545 570 2.8E-7 T 29-03-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site SMALA_RS12275 29369530540ec8a46ac56561d515e9ab 805 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 524 800 25.111 T 29-03-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 SMALA_RS12275 29369530540ec8a46ac56561d515e9ab 805 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 239 481 6.9E-62 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial SMALA_RS12275 29369530540ec8a46ac56561d515e9ab 805 SUPERFAMILY SSF82866 296 490 1.44E-31 T 29-03-2018 SMALA_RS37840 0c8def4457ee0986a3a5d8b4c739692b 3204 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1582 1832 6.0E-89 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS37840 0c8def4457ee0986a3a5d8b4c739692b 3204 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 284 1.2E-89 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS37840 0c8def4457ee0986a3a5d8b4c739692b 3204 Pfam PF08990 Erythronolide synthase docking 2 26 2.8E-10 T 29-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 SMALA_RS37840 0c8def4457ee0986a3a5d8b4c739692b 3204 Gene3D G3DSA:3.40.366.10 564 705 3.7E-41 T 29-03-2018 SMALA_RS37840 0c8def4457ee0986a3a5d8b4c739692b 3204 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3075 3090 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS37840 0c8def4457ee0986a3a5d8b4c739692b 3204 Gene3D G3DSA:3.30.70.250 2257 2299 9.1E-19 T 29-03-2018 SMALA_RS37840 0c8def4457ee0986a3a5d8b4c739692b 3204 Gene3D G3DSA:3.30.70.250 706 751 1.8E-19 T 29-03-2018 SMALA_RS37840 0c8def4457ee0986a3a5d8b4c739692b 3204 SUPERFAMILY SSF51735 978 1188 1.46E-49 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS37840 0c8def4457ee0986a3a5d8b4c739692b 3204 SUPERFAMILY SSF52151 564 692 2.88E-67 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS37840 0c8def4457ee0986a3a5d8b4c739692b 3204 SUPERFAMILY SSF52151 757 855 2.88E-67 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS37840 0c8def4457ee0986a3a5d8b4c739692b 3204 Gene3D G3DSA:3.40.47.10 1583 1844 2.0E-86 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS37840 0c8def4457ee0986a3a5d8b4c739692b 3204 Gene3D G3DSA:3.40.47.10 26 296 1.1E-84 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS37840 0c8def4457ee0986a3a5d8b4c739692b 3204 SUPERFAMILY SSF53901 1580 1955 7.55E-103 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS37840 0c8def4457ee0986a3a5d8b4c739692b 3204 Gene3D G3DSA:3.40.50.720 1194 1454 2.5E-53 T 29-03-2018 SMALA_RS37840 0c8def4457ee0986a3a5d8b4c739692b 3204 Gene3D G3DSA:3.40.50.720 2752 3012 2.9E-55 T 29-03-2018 SMALA_RS37840 0c8def4457ee0986a3a5d8b4c739692b 3204 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2760 2939 8.5E-63 T 29-03-2018 SMALA_RS37840 0c8def4457ee0986a3a5d8b4c739692b 3204 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1202 1381 1.6E-50 T 29-03-2018 SMALA_RS37840 0c8def4457ee0986a3a5d8b4c739692b 3204 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 412 529 1.2E-18 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37840 0c8def4457ee0986a3a5d8b4c739692b 3204 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1960 2078 4.8E-15 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37840 0c8def4457ee0986a3a5d8b4c739692b 3204 Gene3D G3DSA:1.10.1200.10 3027 3120 3.5E-19 T 29-03-2018 SMALA_RS37840 0c8def4457ee0986a3a5d8b4c739692b 3204 SUPERFAMILY SSF55048 691 756 7.19E-14 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS37840 0c8def4457ee0986a3a5d8b4c739692b 3204 SUPERFAMILY SSF52151 2115 2240 2.62E-75 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS37840 0c8def4457ee0986a3a5d8b4c739692b 3204 SUPERFAMILY SSF52151 2302 2406 2.62E-75 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS37840 0c8def4457ee0986a3a5d8b4c739692b 3204 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1514 1529 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS37840 0c8def4457ee0986a3a5d8b4c739692b 3204 SMART SM01294 3049 3116 1.5E-4 T 29-03-2018 SMALA_RS37840 0c8def4457ee0986a3a5d8b4c739692b 3204 SMART SM01294 1488 1555 5.2E-6 T 29-03-2018 SMALA_RS37840 0c8def4457ee0986a3a5d8b4c739692b 3204 Gene3D G3DSA:1.10.1200.10 1481 1582 7.9E-20 T 29-03-2018 SMALA_RS37840 0c8def4457ee0986a3a5d8b4c739692b 3204 Pfam PF08659 KR domain 2760 2938 3.1E-61 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37840 0c8def4457ee0986a3a5d8b4c739692b 3204 Pfam PF08659 KR domain 1202 1380 6.1E-56 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37840 0c8def4457ee0986a3a5d8b4c739692b 3204 SUPERFAMILY SSF53901 31 406 5.24E-105 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS37840 0c8def4457ee0986a3a5d8b4c739692b 3204 SUPERFAMILY SSF47336 3040 3122 5.23E-20 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS37840 0c8def4457ee0986a3a5d8b4c739692b 3204 Gene3D G3DSA:3.40.366.10 752 867 4.5E-27 T 29-03-2018 SMALA_RS37840 0c8def4457ee0986a3a5d8b4c739692b 3204 SUPERFAMILY SSF47336 1483 1597 1.05E-22 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS37840 0c8def4457ee0986a3a5d8b4c739692b 3204 Pfam PF00550 Phosphopantetheine attachment site 1489 1555 1.2E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS37840 0c8def4457ee0986a3a5d8b4c739692b 3204 Pfam PF00550 Phosphopantetheine attachment site 3051 3116 2.8E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS37840 0c8def4457ee0986a3a5d8b4c739692b 3204 SUPERFAMILY SSF51735 2758 2988 1.44E-50 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS37840 0c8def4457ee0986a3a5d8b4c739692b 3204 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 567 865 6.9E-122 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS37840 0c8def4457ee0986a3a5d8b4c739692b 3204 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2118 2420 8.8E-131 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS37840 0c8def4457ee0986a3a5d8b4c739692b 3204 SMART SM00823 Phosphopantetheine attachment site 1487 1559 3.7E-30 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37840 0c8def4457ee0986a3a5d8b4c739692b 3204 SMART SM00823 Phosphopantetheine attachment site 3048 3120 1.4E-28 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37840 0c8def4457ee0986a3a5d8b4c739692b 3204 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1745 1761 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS37840 0c8def4457ee0986a3a5d8b4c739692b 3204 SUPERFAMILY SSF55048 2245 2309 6.02E-12 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS37840 0c8def4457ee0986a3a5d8b4c739692b 3204 SUPERFAMILY SSF51735 1198 1452 3.91E-46 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS37840 0c8def4457ee0986a3a5d8b4c739692b 3204 SUPERFAMILY SSF51735 2531 2748 1.73E-44 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS37840 0c8def4457ee0986a3a5d8b4c739692b 3204 Pfam PF00698 Acyl transferase domain 565 883 4.7E-91 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS37840 0c8def4457ee0986a3a5d8b4c739692b 3204 Pfam PF00698 Acyl transferase domain 2117 2438 3.1E-60 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS37840 0c8def4457ee0986a3a5d8b4c739692b 3204 Gene3D G3DSA:3.40.47.10 1847 2008 5.4E-62 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS37840 0c8def4457ee0986a3a5d8b4c739692b 3204 Gene3D G3DSA:3.40.47.10 299 460 2.5E-62 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS37840 0c8def4457ee0986a3a5d8b4c739692b 3204 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 292 409 2.7E-44 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS37840 0c8def4457ee0986a3a5d8b4c739692b 3204 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1841 1957 1.2E-42 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS37840 0c8def4457ee0986a3a5d8b4c739692b 3204 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 197 213 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS37840 0c8def4457ee0986a3a5d8b4c739692b 3204 Gene3D G3DSA:3.40.366.10 2112 2256 5.4E-50 T 29-03-2018 SMALA_RS37840 0c8def4457ee0986a3a5d8b4c739692b 3204 Gene3D G3DSA:3.40.366.10 2300 2423 1.5E-27 T 29-03-2018 SMALA_RS37840 0c8def4457ee0986a3a5d8b4c739692b 3204 SMART SM00825 Beta-ketoacyl synthase 36 462 4.6E-223 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS37840 0c8def4457ee0986a3a5d8b4c739692b 3204 SMART SM00825 Beta-ketoacyl synthase 1584 2010 5.9E-223 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS20365 c94b3b9dba149f90078464ebc4413e19 221 Pfam PF13419 Haloacid dehalogenase-like hydrolase 3 187 1.0E-15 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS20365 c94b3b9dba149f90078464ebc4413e19 221 Gene3D G3DSA:3.40.50.1000 72 221 7.6E-23 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS20365 c94b3b9dba149f90078464ebc4413e19 221 SUPERFAMILY SSF56784 2 216 1.54E-34 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS20365 c94b3b9dba149f90078464ebc4413e19 221 Gene3D G3DSA:1.10.150.240 18 71 1.4E-9 T 29-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 SMALA_RS35885 17412091b3fbe335ca8f0d97cabf2ac9 499 Gene3D G3DSA:3.40.1010.10 6 149 3.3E-35 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMALA_RS35885 17412091b3fbe335ca8f0d97cabf2ac9 499 Gene3D G3DSA:3.40.1010.10 251 372 1.9E-29 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMALA_RS35885 17412091b3fbe335ca8f0d97cabf2ac9 499 TIGRFAM TIGR01466 cobJ_cbiH: precorrin-3B C17-methyltransferase 254 496 9.5E-83 T 29-03-2018 IPR006363 Precorrin-3B C17-methyltransferase domain GO:0008168|GO:0009236 SMALA_RS35885 17412091b3fbe335ca8f0d97cabf2ac9 499 SUPERFAMILY SSF53790 251 485 1.44E-52 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMALA_RS35885 17412091b3fbe335ca8f0d97cabf2ac9 499 SUPERFAMILY SSF53790 4 244 2.49E-49 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMALA_RS35885 17412091b3fbe335ca8f0d97cabf2ac9 499 Gene3D G3DSA:3.30.950.10 150 220 0.087 T 29-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMALA_RS35885 17412091b3fbe335ca8f0d97cabf2ac9 499 Gene3D G3DSA:3.30.950.10 373 494 5.0E-53 T 29-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMALA_RS35885 17412091b3fbe335ca8f0d97cabf2ac9 499 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 12 26 - T 29-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 SMALA_RS35885 17412091b3fbe335ca8f0d97cabf2ac9 499 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 8 223 6.0E-50 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMALA_RS35885 17412091b3fbe335ca8f0d97cabf2ac9 499 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 254 460 1.8E-35 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMALA_RS35885 17412091b3fbe335ca8f0d97cabf2ac9 499 TIGRFAM TIGR01467 cobI_cbiL: precorrin-2 C(20)-methyltransferase 7 238 3.0E-67 T 29-03-2018 IPR006364 Precorrin-2 C(20)-methyltransferase domain GO:0008757|GO:0009236 SMALA_RS02410 5fdf1e4e1662b0e08504eb5834cd6f1c 655 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 53 72 1.0E-6 T 29-03-2018 SMALA_RS02410 5fdf1e4e1662b0e08504eb5834cd6f1c 655 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 422 444 1.0E-6 T 29-03-2018 SMALA_RS02410 5fdf1e4e1662b0e08504eb5834cd6f1c 655 Pfam PF02910 Fumarate reductase flavoprotein C-term 520 654 1.9E-33 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMALA_RS02410 5fdf1e4e1662b0e08504eb5834cd6f1c 655 SUPERFAMILY SSF46977 511 654 1.22E-37 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMALA_RS02410 5fdf1e4e1662b0e08504eb5834cd6f1c 655 Gene3D G3DSA:3.50.50.60 44 514 1.0E-55 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS02410 5fdf1e4e1662b0e08504eb5834cd6f1c 655 SUPERFAMILY SSF51905 423 476 2.09E-49 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS02410 5fdf1e4e1662b0e08504eb5834cd6f1c 655 SUPERFAMILY SSF51905 48 294 2.09E-49 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS02410 5fdf1e4e1662b0e08504eb5834cd6f1c 655 Gene3D G3DSA:1.20.58.100 515 617 7.8E-22 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMALA_RS02410 5fdf1e4e1662b0e08504eb5834cd6f1c 655 SUPERFAMILY SSF56425 278 420 4.49E-33 T 29-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMALA_RS02410 5fdf1e4e1662b0e08504eb5834cd6f1c 655 TIGRFAM TIGR01811 sdhA_Bsu: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 53 654 0.0 T 29-03-2018 IPR011280 Succinate dehydrogenase/fumarate reductase flavoprotein subunit, low-GC Gram-positive bacteria KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279 SMALA_RS02410 5fdf1e4e1662b0e08504eb5834cd6f1c 655 Pfam PF00890 FAD binding domain 53 458 2.2E-60 T 29-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMALA_RS36310 5766cca564e06070982c17d4062edd67 435 SUPERFAMILY SSF46785 12 75 2.61E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS36310 5766cca564e06070982c17d4062edd67 435 Pfam PF00480 ROK family 86 401 1.6E-35 T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 SMALA_RS36310 5766cca564e06070982c17d4062edd67 435 Gene3D G3DSA:3.30.420.40 222 412 2.9E-40 T 29-03-2018 SMALA_RS36310 5766cca564e06070982c17d4062edd67 435 SUPERFAMILY SSF53067 83 406 1.2E-45 T 29-03-2018 SMALA_RS36310 5766cca564e06070982c17d4062edd67 435 Gene3D G3DSA:3.30.420.40 77 221 5.2E-26 T 29-03-2018 SMALA_RS36310 5766cca564e06070982c17d4062edd67 435 Gene3D G3DSA:1.10.10.10 10 76 3.5E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS18750 8ec27f7de05e195bdda1f597d013a212 608 Pfam PF00326 Prolyl oligopeptidase family 392 594 1.0E-39 T 29-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 SMALA_RS18750 8ec27f7de05e195bdda1f597d013a212 608 SUPERFAMILY SSF53474 347 593 1.08E-53 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS18750 8ec27f7de05e195bdda1f597d013a212 608 Gene3D G3DSA:2.130.10.150 16 109 1.3E-9 T 29-03-2018 SMALA_RS18750 8ec27f7de05e195bdda1f597d013a212 608 Gene3D G3DSA:2.130.10.120 110 318 3.7E-14 T 29-03-2018 SMALA_RS18750 8ec27f7de05e195bdda1f597d013a212 608 SUPERFAMILY SSF82171 23 321 3.69E-25 T 29-03-2018 SMALA_RS18750 8ec27f7de05e195bdda1f597d013a212 608 Gene3D G3DSA:3.40.50.1820 319 595 5.2E-45 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS42595 0feca27d0bac5e8b905b07bed7054003 280 Gene3D G3DSA:1.10.1660.10 67 115 2.2E-6 T 29-03-2018 SMALA_RS42595 0feca27d0bac5e8b905b07bed7054003 280 Pfam PF00376 MerR family regulatory protein 12 49 9.6E-14 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS42595 0feca27d0bac5e8b905b07bed7054003 280 SMART SM00422 11 80 4.2E-19 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS42595 0feca27d0bac5e8b905b07bed7054003 280 SUPERFAMILY SSF46955 12 112 1.39E-22 T 29-03-2018 IPR009061 Putative DNA-binding domain SMALA_RS42595 0feca27d0bac5e8b905b07bed7054003 280 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 12 23 5.8E-6 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS42595 0feca27d0bac5e8b905b07bed7054003 280 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 23 36 5.8E-6 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS42595 0feca27d0bac5e8b905b07bed7054003 280 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 47 67 5.8E-6 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS42595 0feca27d0bac5e8b905b07bed7054003 280 Gene3D G3DSA:1.10.1660.10 8 66 6.2E-17 T 29-03-2018 SMALA_RS42355 2f9f5d4c827fd4d7c50d8ee54bc9169b 217 Gene3D G3DSA:3.10.20.30 63 139 7.3E-29 T 29-03-2018 IPR012675 Beta-grasp domain SMALA_RS42355 2f9f5d4c827fd4d7c50d8ee54bc9169b 217 Gene3D G3DSA:1.20.5.510 19 49 3.8E-4 T 29-03-2018 SMALA_RS42355 2f9f5d4c827fd4d7c50d8ee54bc9169b 217 SUPERFAMILY SSF47741 149 215 5.23E-27 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 SMALA_RS42355 2f9f5d4c827fd4d7c50d8ee54bc9169b 217 Gene3D G3DSA:1.10.150.120 140 217 5.1E-32 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 SMALA_RS42355 2f9f5d4c827fd4d7c50d8ee54bc9169b 217 Pfam PF01799 [2Fe-2S] binding domain 138 210 3.7E-28 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 SMALA_RS42355 2f9f5d4c827fd4d7c50d8ee54bc9169b 217 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 104 112 - T 29-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 SMALA_RS42355 2f9f5d4c827fd4d7c50d8ee54bc9169b 217 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 71 124 6.8E-8 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SMALA_RS42355 2f9f5d4c827fd4d7c50d8ee54bc9169b 217 SUPERFAMILY SSF54292 66 153 4.06E-27 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SMALA_RS07905 00b7120a228ee553c7b1ab44f809d73c 1035 SMART SM00490 470 564 1.2E-5 T 29-03-2018 IPR001650 Helicase, C-terminal SMALA_RS07905 00b7120a228ee553c7b1ab44f809d73c 1035 Pfam PF00176 SNF2 family N-terminal domain 120 282 3.4E-8 T 29-03-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 SMALA_RS07905 00b7120a228ee553c7b1ab44f809d73c 1035 SUPERFAMILY SSF52540 222 283 9.0E-26 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS07905 00b7120a228ee553c7b1ab44f809d73c 1035 SUPERFAMILY SSF52540 428 581 9.0E-26 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS07905 00b7120a228ee553c7b1ab44f809d73c 1035 Pfam PF00271 Helicase conserved C-terminal domain 454 564 3.0E-8 T 29-03-2018 IPR001650 Helicase, C-terminal SMALA_RS07905 00b7120a228ee553c7b1ab44f809d73c 1035 Gene3D G3DSA:3.40.50.300 435 1023 3.5E-16 T 29-03-2018 SMALA_RS07905 00b7120a228ee553c7b1ab44f809d73c 1035 Gene3D G3DSA:3.40.50.10810 84 347 2.3E-22 T 29-03-2018 SMALA_RS07905 00b7120a228ee553c7b1ab44f809d73c 1035 SMART SM00487 95 296 1.7E-12 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain SMALA_RS07905 00b7120a228ee553c7b1ab44f809d73c 1035 SUPERFAMILY SSF52540 69 297 2.84E-28 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS23835 dcdee1485f52806090e95325e434f0e6 1096 Pfam PF03572 Peptidase family S41 888 1041 1.8E-22 T 29-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 SMALA_RS23835 dcdee1485f52806090e95325e434f0e6 1096 Pfam PF14685 Tricorn protease PDZ domain 770 858 1.9E-23 T 29-03-2018 IPR029414 Tricorn protease, PDZ domain SMALA_RS23835 dcdee1485f52806090e95325e434f0e6 1096 SUPERFAMILY SSF50156 770 849 1.42E-11 T 29-03-2018 IPR001478 PDZ domain GO:0005515 SMALA_RS23835 dcdee1485f52806090e95325e434f0e6 1096 SUPERFAMILY SSF69304 15 282 9.15E-26 T 29-03-2018 SMALA_RS23835 dcdee1485f52806090e95325e434f0e6 1096 SUPERFAMILY SSF69304 378 510 2.35E-23 T 29-03-2018 SMALA_RS23835 dcdee1485f52806090e95325e434f0e6 1096 SUPERFAMILY SSF69304 567 664 2.35E-23 T 29-03-2018 SMALA_RS23835 dcdee1485f52806090e95325e434f0e6 1096 SUPERFAMILY SSF52096 860 1068 3.48E-64 T 29-03-2018 IPR029045 ClpP/crotonase-like domain SMALA_RS23835 dcdee1485f52806090e95325e434f0e6 1096 SUPERFAMILY SSF52096 685 764 3.48E-64 T 29-03-2018 IPR029045 ClpP/crotonase-like domain SMALA_RS23835 dcdee1485f52806090e95325e434f0e6 1096 PIRSF PIRSF036421 6 1076 0.0 T 29-03-2018 IPR012393 Tricorn protease GO:0008236 SMALA_RS23835 dcdee1485f52806090e95325e434f0e6 1096 Gene3D G3DSA:2.120.10.60 8 282 6.0E-26 T 29-03-2018 SMALA_RS23835 dcdee1485f52806090e95325e434f0e6 1096 Pfam PF07676 WD40-like Beta Propeller Repeat 60 81 0.026 T 29-03-2018 IPR011659 WD40-like Beta Propeller SMALA_RS23835 dcdee1485f52806090e95325e434f0e6 1096 Pfam PF07676 WD40-like Beta Propeller Repeat 476 508 5.1E-5 T 29-03-2018 IPR011659 WD40-like Beta Propeller SMALA_RS23835 dcdee1485f52806090e95325e434f0e6 1096 Pfam PF14684 Tricorn protease C1 domain 688 755 8.7E-27 T 29-03-2018 IPR028204 Tricorn protease C1 domain SMALA_RS23835 dcdee1485f52806090e95325e434f0e6 1096 Gene3D G3DSA:2.130.10.10 305 677 7.3E-64 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMALA_RS23835 dcdee1485f52806090e95325e434f0e6 1096 Gene3D G3DSA:3.90.226.10 865 1076 3.0E-35 T 29-03-2018 SMALA_RS23835 dcdee1485f52806090e95325e434f0e6 1096 Gene3D G3DSA:2.30.42.10 768 864 1.8E-8 T 29-03-2018 SMALA_RS23835 dcdee1485f52806090e95325e434f0e6 1096 Gene3D G3DSA:3.30.750.44 688 755 7.3E-24 T 29-03-2018 SMALA_RS23835 dcdee1485f52806090e95325e434f0e6 1096 SMART SM00245 851 1043 1.1E-12 T 29-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 SMALA_RS37110 6679ab201f6305802d54412f384c3257 698 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 481 605 1.3E-22 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 SMALA_RS37110 6679ab201f6305802d54412f384c3257 698 SMART SM00382 476 608 1.2E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS37110 6679ab201f6305802d54412f384c3257 698 Gene3D G3DSA:3.40.50.300 273 626 2.5E-28 T 29-03-2018 SMALA_RS37110 6679ab201f6305802d54412f384c3257 698 SUPERFAMILY SSF52540 432 674 4.28E-36 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS26120 7141112eb25765ee3d246441aeaf3c8d 615 SUPERFAMILY SSF81901 260 447 3.47E-27 T 29-03-2018 SMALA_RS26120 7141112eb25765ee3d246441aeaf3c8d 615 Gene3D G3DSA:1.25.40.10 229 330 1.8E-18 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS26120 7141112eb25765ee3d246441aeaf3c8d 615 Gene3D G3DSA:1.25.40.10 21 148 1.2E-14 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS26120 7141112eb25765ee3d246441aeaf3c8d 615 Gene3D G3DSA:1.25.40.10 484 613 5.6E-15 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS26120 7141112eb25765ee3d246441aeaf3c8d 615 SUPERFAMILY SSF81901 42 173 9.59E-16 T 29-03-2018 SMALA_RS26120 7141112eb25765ee3d246441aeaf3c8d 615 Gene3D G3DSA:1.25.40.10 350 458 7.5E-15 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS26120 7141112eb25765ee3d246441aeaf3c8d 615 Pfam PF08238 Sel1 repeat 547 563 6.7 T 29-03-2018 IPR006597 Sel1-like repeat SMALA_RS26120 7141112eb25765ee3d246441aeaf3c8d 615 Pfam PF08238 Sel1 repeat 102 133 0.47 T 29-03-2018 IPR006597 Sel1-like repeat SMALA_RS26120 7141112eb25765ee3d246441aeaf3c8d 615 Pfam PF08238 Sel1 repeat 166 213 0.037 T 29-03-2018 IPR006597 Sel1-like repeat SMALA_RS26120 7141112eb25765ee3d246441aeaf3c8d 615 Pfam PF08238 Sel1 repeat 149 164 5.3 T 29-03-2018 IPR006597 Sel1-like repeat SMALA_RS26120 7141112eb25765ee3d246441aeaf3c8d 615 Pfam PF08238 Sel1 repeat 248 277 21.0 T 29-03-2018 IPR006597 Sel1-like repeat SMALA_RS26120 7141112eb25765ee3d246441aeaf3c8d 615 Pfam PF08238 Sel1 repeat 361 373 22.0 T 29-03-2018 IPR006597 Sel1-like repeat SMALA_RS26120 7141112eb25765ee3d246441aeaf3c8d 615 SMART SM00671 374 405 0.27 T 29-03-2018 IPR006597 Sel1-like repeat SMALA_RS26120 7141112eb25765ee3d246441aeaf3c8d 615 SMART SM00671 246 277 7.9 T 29-03-2018 IPR006597 Sel1-like repeat SMALA_RS26120 7141112eb25765ee3d246441aeaf3c8d 615 SMART SM00671 500 531 30.0 T 29-03-2018 IPR006597 Sel1-like repeat SMALA_RS26120 7141112eb25765ee3d246441aeaf3c8d 615 SMART SM00671 406 437 360.0 T 29-03-2018 IPR006597 Sel1-like repeat SMALA_RS26120 7141112eb25765ee3d246441aeaf3c8d 615 SMART SM00671 278 309 13.0 T 29-03-2018 IPR006597 Sel1-like repeat SMALA_RS26120 7141112eb25765ee3d246441aeaf3c8d 615 SMART SM00671 532 563 2.7 T 29-03-2018 IPR006597 Sel1-like repeat SMALA_RS26120 7141112eb25765ee3d246441aeaf3c8d 615 SMART SM00671 310 341 14.0 T 29-03-2018 IPR006597 Sel1-like repeat SMALA_RS26120 7141112eb25765ee3d246441aeaf3c8d 615 SMART SM00671 342 373 18.0 T 29-03-2018 IPR006597 Sel1-like repeat SMALA_RS26120 7141112eb25765ee3d246441aeaf3c8d 615 SMART SM00671 102 133 0.17 T 29-03-2018 IPR006597 Sel1-like repeat SMALA_RS26120 7141112eb25765ee3d246441aeaf3c8d 615 SMART SM00671 214 245 210.0 T 29-03-2018 IPR006597 Sel1-like repeat SMALA_RS26120 7141112eb25765ee3d246441aeaf3c8d 615 SMART SM00671 134 164 9.3 T 29-03-2018 IPR006597 Sel1-like repeat SMALA_RS26120 7141112eb25765ee3d246441aeaf3c8d 615 SUPERFAMILY SSF81901 152 282 3.92E-16 T 29-03-2018 SMALA_RS26120 7141112eb25765ee3d246441aeaf3c8d 615 Pfam PF13432 Tetratricopeptide repeat 314 337 0.015 T 29-03-2018 SMALA_RS26120 7141112eb25765ee3d246441aeaf3c8d 615 Pfam PF13432 Tetratricopeptide repeat 491 532 0.014 T 29-03-2018 SMALA_RS26120 7141112eb25765ee3d246441aeaf3c8d 615 Gene3D G3DSA:2.60.40.1180 331 349 0.052 T 29-03-2018 SMALA_RS26120 7141112eb25765ee3d246441aeaf3c8d 615 Gene3D G3DSA:2.60.40.1180 149 184 0.0039 T 29-03-2018 SMALA_RS26120 7141112eb25765ee3d246441aeaf3c8d 615 Gene3D G3DSA:2.60.40.1180 198 228 0.0016 T 29-03-2018 SMALA_RS26120 7141112eb25765ee3d246441aeaf3c8d 615 SUPERFAMILY SSF81901 487 597 2.49E-18 T 29-03-2018 SMALA_RS26120 7141112eb25765ee3d246441aeaf3c8d 615 Pfam PF13374 Tetratricopeptide repeat 379 403 0.0049 T 29-03-2018 SMALA_RS26120 7141112eb25765ee3d246441aeaf3c8d 615 Pfam PF13374 Tetratricopeptide repeat 279 306 0.0083 T 29-03-2018 SMALA_RS28080 3afa723dd6495a81ee076935cd3a9ca2 216 SUPERFAMILY SSF52172 4 133 4.7E-30 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS28080 3afa723dd6495a81ee076935cd3a9ca2 216 ProSitePatterns PS00622 LuxR-type HTH domain signature. 168 195 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS28080 3afa723dd6495a81ee076935cd3a9ca2 216 Gene3D G3DSA:1.10.10.10 129 215 5.0E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS28080 3afa723dd6495a81ee076935cd3a9ca2 216 SUPERFAMILY SSF46894 147 213 3.4E-20 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS28080 3afa723dd6495a81ee076935cd3a9ca2 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 168 6.6E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS28080 3afa723dd6495a81ee076935cd3a9ca2 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 184 6.6E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS28080 3afa723dd6495a81ee076935cd3a9ca2 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 184 196 6.6E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS28080 3afa723dd6495a81ee076935cd3a9ca2 216 Pfam PF00196 Bacterial regulatory proteins, luxR family 153 208 2.7E-17 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS28080 3afa723dd6495a81ee076935cd3a9ca2 216 Pfam PF00072 Response regulator receiver domain 6 117 1.2E-23 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS28080 3afa723dd6495a81ee076935cd3a9ca2 216 Gene3D G3DSA:3.40.50.2300 3 128 5.0E-31 T 29-03-2018 SMALA_RS28080 3afa723dd6495a81ee076935cd3a9ca2 216 SMART SM00448 4 117 3.6E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS28080 3afa723dd6495a81ee076935cd3a9ca2 216 SMART SM00421 151 208 7.6E-24 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS40715 52d69f7d0dd2ce79056a14e680898fe0 257 Gene3D G3DSA:3.30.450.40 83 257 2.0E-37 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS40715 52d69f7d0dd2ce79056a14e680898fe0 257 Gene3D G3DSA:1.10.10.10 3 78 1.2E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS40715 52d69f7d0dd2ce79056a14e680898fe0 257 SUPERFAMILY SSF46785 20 87 2.62E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS40715 52d69f7d0dd2ce79056a14e680898fe0 257 Pfam PF09339 IclR helix-turn-helix domain 21 70 2.2E-11 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMALA_RS40715 52d69f7d0dd2ce79056a14e680898fe0 257 Pfam PF01614 Bacterial transcriptional regulator 139 254 2.2E-18 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal SMALA_RS40715 52d69f7d0dd2ce79056a14e680898fe0 257 SMART SM00346 18 107 2.1E-16 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMALA_RS40715 52d69f7d0dd2ce79056a14e680898fe0 257 SUPERFAMILY SSF55781 75 257 1.83E-34 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS31010 ed2574d8b47ba1dcfe1c96c22e83c77e 699 PIRSF PIRSF038927 1 698 0.0 T 29-03-2018 IPR024712 Catalase, mono-functional, haem-containing, clade 2 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 SMALA_RS31010 ed2574d8b47ba1dcfe1c96c22e83c77e 699 PRINTS PR00067 Catalase signature 309 336 1.9E-69 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMALA_RS31010 ed2574d8b47ba1dcfe1c96c22e83c77e 699 PRINTS PR00067 Catalase signature 121 138 1.9E-69 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMALA_RS31010 ed2574d8b47ba1dcfe1c96c22e83c77e 699 PRINTS PR00067 Catalase signature 37 60 1.9E-69 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMALA_RS31010 ed2574d8b47ba1dcfe1c96c22e83c77e 699 PRINTS PR00067 Catalase signature 341 367 1.9E-69 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMALA_RS31010 ed2574d8b47ba1dcfe1c96c22e83c77e 699 PRINTS PR00067 Catalase signature 100 118 1.9E-69 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMALA_RS31010 ed2574d8b47ba1dcfe1c96c22e83c77e 699 PRINTS PR00067 Catalase signature 140 158 1.9E-69 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMALA_RS31010 ed2574d8b47ba1dcfe1c96c22e83c77e 699 Pfam PF00199 Catalase 24 407 7.3E-178 T 29-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMALA_RS31010 ed2574d8b47ba1dcfe1c96c22e83c77e 699 ProSitePatterns PS00438 Catalase proximal active site signature. 60 76 - T 29-03-2018 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMALA_RS31010 ed2574d8b47ba1dcfe1c96c22e83c77e 699 Pfam PF06628 Catalase-related immune-responsive 438 501 1.9E-21 T 29-03-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMALA_RS31010 ed2574d8b47ba1dcfe1c96c22e83c77e 699 Gene3D G3DSA:2.40.180.10 1 379 4.3E-164 T 29-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMALA_RS31010 ed2574d8b47ba1dcfe1c96c22e83c77e 699 Pfam PF01965 DJ-1/PfpI family 537 643 1.8E-13 T 29-03-2018 IPR002818 DJ-1/PfpI SMALA_RS31010 ed2574d8b47ba1dcfe1c96c22e83c77e 699 SUPERFAMILY SSF56634 14 522 8.37E-214 T 29-03-2018 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMALA_RS31010 ed2574d8b47ba1dcfe1c96c22e83c77e 699 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 354 362 - T 29-03-2018 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMALA_RS31010 ed2574d8b47ba1dcfe1c96c22e83c77e 699 SUPERFAMILY SSF52317 534 693 5.54E-23 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS31010 ed2574d8b47ba1dcfe1c96c22e83c77e 699 SMART SM01060 24 411 2.4E-267 T 29-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMALA_RS31010 ed2574d8b47ba1dcfe1c96c22e83c77e 699 Gene3D G3DSA:3.40.50.880 533 699 1.3E-29 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS32715 3cc5f941b39988de668e6db2408a30bd 490 SUPERFAMILY SSF103473 253 473 4.19E-65 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS32715 3cc5f941b39988de668e6db2408a30bd 490 SUPERFAMILY SSF103473 4 202 4.19E-65 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS32715 3cc5f941b39988de668e6db2408a30bd 490 Pfam PF07690 Major Facilitator Superfamily 24 414 7.6E-51 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS32715 3cc5f941b39988de668e6db2408a30bd 490 Gene3D G3DSA:1.20.1250.20 264 477 3.4E-27 T 29-03-2018 SMALA_RS32715 3cc5f941b39988de668e6db2408a30bd 490 Gene3D G3DSA:1.20.1250.20 10 207 8.5E-30 T 29-03-2018 SMALA_RS10995 728da2025aa3819a5947cb688b65517c 1180 SUPERFAMILY SSF48452 97 256 2.61E-32 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS10995 728da2025aa3819a5947cb688b65517c 1180 SUPERFAMILY SSF48452 874 1033 8.47E-13 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS10995 728da2025aa3819a5947cb688b65517c 1180 SMART SM01043 101 243 5.9E-45 T 29-03-2018 IPR005158 Bacterial transcriptional activator domain SMALA_RS10995 728da2025aa3819a5947cb688b65517c 1180 SMART SM00862 22 94 1.9E-8 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS10995 728da2025aa3819a5947cb688b65517c 1180 SUPERFAMILY SSF52540 336 603 1.04E-18 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS10995 728da2025aa3819a5947cb688b65517c 1180 Gene3D G3DSA:1.10.10.10 8 102 1.5E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS10995 728da2025aa3819a5947cb688b65517c 1180 Gene3D G3DSA:3.40.50.300 329 489 4.0E-11 T 29-03-2018 SMALA_RS10995 728da2025aa3819a5947cb688b65517c 1180 Pfam PF00486 Transcriptional regulatory protein, C terminal 31 93 1.4E-5 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS10995 728da2025aa3819a5947cb688b65517c 1180 PRINTS PR00364 Disease resistance protein signature 443 457 2.4E-5 T 29-03-2018 SMALA_RS10995 728da2025aa3819a5947cb688b65517c 1180 PRINTS PR00364 Disease resistance protein signature 536 550 2.4E-5 T 29-03-2018 SMALA_RS10995 728da2025aa3819a5947cb688b65517c 1180 PRINTS PR00364 Disease resistance protein signature 358 373 2.4E-5 T 29-03-2018 SMALA_RS10995 728da2025aa3819a5947cb688b65517c 1180 Gene3D G3DSA:1.25.40.10 993 1166 1.7E-4 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS10995 728da2025aa3819a5947cb688b65517c 1180 Gene3D G3DSA:1.25.40.10 717 992 2.5E-15 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS10995 728da2025aa3819a5947cb688b65517c 1180 Gene3D G3DSA:1.25.40.10 103 265 2.5E-26 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS10995 728da2025aa3819a5947cb688b65517c 1180 Pfam PF03704 Bacterial transcriptional activator domain 101 243 4.3E-42 T 29-03-2018 IPR005158 Bacterial transcriptional activator domain SMALA_RS10995 728da2025aa3819a5947cb688b65517c 1180 SUPERFAMILY SSF46894 12 94 1.25E-9 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS35965 09ad5579acf0031148c4f9321a3e5d10 1657 Pfam PF00550 Phosphopantetheine attachment site 1533 1594 6.7E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS35965 09ad5579acf0031148c4f9321a3e5d10 1657 Gene3D G3DSA:3.30.70.250 727 769 2.8E-20 T 29-03-2018 SMALA_RS35965 09ad5579acf0031148c4f9321a3e5d10 1657 SUPERFAMILY SSF51735 997 1225 3.11E-41 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS35965 09ad5579acf0031148c4f9321a3e5d10 1657 Gene3D G3DSA:3.40.366.10 588 726 4.8E-39 T 29-03-2018 SMALA_RS35965 09ad5579acf0031148c4f9321a3e5d10 1657 Gene3D G3DSA:3.40.47.10 301 462 4.2E-58 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS35965 09ad5579acf0031148c4f9321a3e5d10 1657 SMART SM00825 Beta-ketoacyl synthase 38 464 7.1E-211 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS35965 09ad5579acf0031148c4f9321a3e5d10 1657 Gene3D G3DSA:1.10.1200.10 1497 1606 1.2E-18 T 29-03-2018 SMALA_RS35965 09ad5579acf0031148c4f9321a3e5d10 1657 SUPERFAMILY SSF52151 588 713 1.36E-62 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS35965 09ad5579acf0031148c4f9321a3e5d10 1657 SUPERFAMILY SSF52151 778 873 1.36E-62 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS35965 09ad5579acf0031148c4f9321a3e5d10 1657 Pfam PF08990 Erythronolide synthase docking 5 27 1.2E-8 T 29-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 SMALA_RS35965 09ad5579acf0031148c4f9321a3e5d10 1657 SMART SM00823 Phosphopantetheine attachment site 1526 1598 3.5E-30 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS35965 09ad5579acf0031148c4f9321a3e5d10 1657 SUPERFAMILY SSF47336 1518 1603 1.83E-21 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS35965 09ad5579acf0031148c4f9321a3e5d10 1657 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 416 552 2.6E-13 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS35965 09ad5579acf0031148c4f9321a3e5d10 1657 Pfam PF00698 Acyl transferase domain 589 905 4.6E-88 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS35965 09ad5579acf0031148c4f9321a3e5d10 1657 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 591 886 3.9E-113 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS35965 09ad5579acf0031148c4f9321a3e5d10 1657 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 294 411 1.4E-40 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS35965 09ad5579acf0031148c4f9321a3e5d10 1657 Gene3D G3DSA:3.40.50.720 1230 1491 2.9E-55 T 29-03-2018 SMALA_RS35965 09ad5579acf0031148c4f9321a3e5d10 1657 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 36 286 2.2E-91 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS35965 09ad5579acf0031148c4f9321a3e5d10 1657 SUPERFAMILY SSF55048 712 777 1.16E-14 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS35965 09ad5579acf0031148c4f9321a3e5d10 1657 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1553 1568 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS35965 09ad5579acf0031148c4f9321a3e5d10 1657 Gene3D G3DSA:3.40.366.10 770 888 4.3E-25 T 29-03-2018 SMALA_RS35965 09ad5579acf0031148c4f9321a3e5d10 1657 Pfam PF08659 KR domain 1238 1418 1.9E-60 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS35965 09ad5579acf0031148c4f9321a3e5d10 1657 SUPERFAMILY SSF53901 32 408 3.19E-101 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS35965 09ad5579acf0031148c4f9321a3e5d10 1657 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1238 1420 4.1E-56 T 29-03-2018 SMALA_RS35965 09ad5579acf0031148c4f9321a3e5d10 1657 SMART SM01294 1527 1594 2.6E-6 T 29-03-2018 SMALA_RS35965 09ad5579acf0031148c4f9321a3e5d10 1657 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 199 215 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS35965 09ad5579acf0031148c4f9321a3e5d10 1657 Gene3D G3DSA:3.40.47.10 28 298 4.8E-85 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS35965 09ad5579acf0031148c4f9321a3e5d10 1657 SUPERFAMILY SSF51735 1236 1462 2.95E-48 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS05415 2f71d0301c2e5e5791c6bde33431ece5 495 SUPERFAMILY SSF53067 252 464 1.39E-22 T 29-03-2018 SMALA_RS05415 2f71d0301c2e5e5791c6bde33431ece5 495 SUPERFAMILY SSF53067 11 248 1.4E-47 T 29-03-2018 SMALA_RS05415 2f71d0301c2e5e5791c6bde33431ece5 495 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 11 248 3.5E-37 T 29-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 SMALA_RS05415 2f71d0301c2e5e5791c6bde33431ece5 495 PIRSF PIRSF000538 8 478 9.9E-67 T 29-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 SMALA_RS05415 2f71d0301c2e5e5791c6bde33431ece5 495 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 313 435 2.7E-14 T 29-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 SMALA_RS05415 2f71d0301c2e5e5791c6bde33431ece5 495 Gene3D G3DSA:3.30.420.40 246 477 2.1E-31 T 29-03-2018 SMALA_RS05415 2f71d0301c2e5e5791c6bde33431ece5 495 Gene3D G3DSA:3.30.420.40 7 245 7.4E-62 T 29-03-2018 SMALA_RS00430 ee37cde22cdb6360b17fdd7e3733396b 606 ProSitePatterns PS00012 Phosphopantetheine attachment site. 73 88 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS00430 ee37cde22cdb6360b17fdd7e3733396b 606 SUPERFAMILY SSF52777 132 314 7.78E-38 T 29-03-2018 SMALA_RS00430 ee37cde22cdb6360b17fdd7e3733396b 606 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 454 582 1.2E-21 T 29-03-2018 IPR010060 Non-ribosomal peptide synthase SMALA_RS00430 ee37cde22cdb6360b17fdd7e3733396b 606 SMART SM00823 Phosphopantetheine attachment site 49 117 0.0013 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS00430 ee37cde22cdb6360b17fdd7e3733396b 606 Gene3D G3DSA:3.30.559.10 113 339 4.3E-30 T 29-03-2018 SMALA_RS00430 ee37cde22cdb6360b17fdd7e3733396b 606 SUPERFAMILY SSF52777 320 581 7.23E-32 T 29-03-2018 SMALA_RS00430 ee37cde22cdb6360b17fdd7e3733396b 606 Pfam PF00550 Phosphopantetheine attachment site 51 112 3.9E-9 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS00430 ee37cde22cdb6360b17fdd7e3733396b 606 Gene3D G3DSA:1.10.1200.10 30 112 1.1E-17 T 29-03-2018 SMALA_RS00430 ee37cde22cdb6360b17fdd7e3733396b 606 Pfam PF00668 Condensation domain 128 579 5.4E-51 T 29-03-2018 IPR001242 Condensation domain SMALA_RS00430 ee37cde22cdb6360b17fdd7e3733396b 606 SUPERFAMILY SSF47336 44 111 1.96E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS28190 c23f28937791b1a6f0b61c4e5d2f99be 119 Gene3D G3DSA:3.40.1350.10 10 118 1.6E-34 T 29-03-2018 SMALA_RS28190 c23f28937791b1a6f0b61c4e5d2f99be 119 SUPERFAMILY SSF52980 9 106 4.18E-20 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 SMALA_RS28190 c23f28937791b1a6f0b61c4e5d2f99be 119 Pfam PF02021 Uncharacterised protein family UPF0102 11 102 7.7E-27 T 29-03-2018 IPR003509 Uncharacterised protein family UPF0102 SMALA_RS28190 c23f28937791b1a6f0b61c4e5d2f99be 119 Hamap MF_00048 UPF0102 protein YraN [yraN]. 4 115 20.368 T 29-03-2018 IPR003509 Uncharacterised protein family UPF0102 SMALA_RS36880 284c828db8d88aef48748d66a6c267d9 297 SUPERFAMILY SSF51445 90 295 5.53E-66 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS36880 284c828db8d88aef48748d66a6c267d9 297 SMART SM00641 92 201 6.3E-40 T 29-03-2018 IPR018077 Glycoside hydrolase, family 25 subgroup SMALA_RS36880 284c828db8d88aef48748d66a6c267d9 297 Pfam PF01183 Glycosyl hydrolases family 25 95 279 1.0E-49 T 29-03-2018 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 SMALA_RS36880 284c828db8d88aef48748d66a6c267d9 297 Gene3D G3DSA:3.20.20.80 73 297 1.5E-64 T 29-03-2018 SMALA_RS27740 b0cf6eee68609306f81735248301507e 496 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 19 440 1.7E-73 T 29-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 SMALA_RS27740 b0cf6eee68609306f81735248301507e 496 Pfam PF07690 Major Facilitator Superfamily 23 416 2.6E-51 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS27740 b0cf6eee68609306f81735248301507e 496 Gene3D G3DSA:1.20.1250.20 10 203 3.9E-33 T 29-03-2018 SMALA_RS27740 b0cf6eee68609306f81735248301507e 496 SUPERFAMILY SSF103473 253 481 1.07E-63 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS27740 b0cf6eee68609306f81735248301507e 496 SUPERFAMILY SSF103473 8 201 1.07E-63 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS27740 b0cf6eee68609306f81735248301507e 496 Gene3D G3DSA:1.20.1250.20 265 488 2.6E-21 T 29-03-2018 SMALA_RS27740 b0cf6eee68609306f81735248301507e 496 PRINTS PR01036 Tetracycline resistance protein TetB signature 21 45 1.1E-6 T 29-03-2018 SMALA_RS27740 b0cf6eee68609306f81735248301507e 496 PRINTS PR01036 Tetracycline resistance protein TetB signature 143 167 1.1E-6 T 29-03-2018 SMALA_RS27740 b0cf6eee68609306f81735248301507e 496 PRINTS PR01036 Tetracycline resistance protein TetB signature 168 192 1.1E-6 T 29-03-2018 SMALA_RS27315 6996d7807d742211eeffab72717a9965 578 TIGRFAM TIGR02456 treS_nterm: trehalose synthase 23 567 1.0E-300 T 29-03-2018 IPR012810 Trehalose synthase/alpha-amylase, N-terminal GO:0003824|GO:0005975 KEGG: 00500+5.4.99.16|MetaCyc: PWY-2622 SMALA_RS27315 6996d7807d742211eeffab72717a9965 578 Pfam PF16657 Maltogenic Amylase, C-terminal domain 481 564 2.2E-23 T 29-03-2018 IPR032091 Maltogenic Amylase, C-terminal SMALA_RS27315 6996d7807d742211eeffab72717a9965 578 SUPERFAMILY SSF51445 371 478 6.38E-134 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS27315 6996d7807d742211eeffab72717a9965 578 SUPERFAMILY SSF51445 20 344 6.38E-134 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS27315 6996d7807d742211eeffab72717a9965 578 SMART SM00642 31 433 1.5E-121 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SMALA_RS27315 6996d7807d742211eeffab72717a9965 578 Gene3D G3DSA:3.20.20.80 28 480 2.8E-123 T 29-03-2018 SMALA_RS27315 6996d7807d742211eeffab72717a9965 578 Pfam PF00128 Alpha amylase, catalytic domain 46 402 4.4E-75 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SMALA_RS27315 6996d7807d742211eeffab72717a9965 578 Gene3D G3DSA:2.60.40.1180 481 576 1.7E-24 T 29-03-2018 SMALA_RS27315 6996d7807d742211eeffab72717a9965 578 SUPERFAMILY SSF51011 486 567 3.6E-16 T 29-03-2018 SMALA_RS42455 99a48b8d29ff767be529fe3ff5e3e5a2 347 Pfam PF00107 Zinc-binding dehydrogenase 159 250 3.1E-20 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMALA_RS42455 99a48b8d29ff767be529fe3ff5e3e5a2 347 SUPERFAMILY SSF51735 121 310 3.63E-37 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS42455 99a48b8d29ff767be529fe3ff5e3e5a2 347 SMART SM00829 20 343 1.4E-13 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS42455 99a48b8d29ff767be529fe3ff5e3e5a2 347 SUPERFAMILY SSF50129 15 146 7.91E-27 T 29-03-2018 IPR011032 GroES-like SMALA_RS42455 99a48b8d29ff767be529fe3ff5e3e5a2 347 Gene3D G3DSA:3.90.180.10 248 347 6.3E-7 T 29-03-2018 SMALA_RS42455 99a48b8d29ff767be529fe3ff5e3e5a2 347 Gene3D G3DSA:3.40.50.720 157 247 2.7E-23 T 29-03-2018 SMALA_RS42455 99a48b8d29ff767be529fe3ff5e3e5a2 347 Gene3D G3DSA:3.90.180.10 4 156 5.5E-36 T 29-03-2018 SMALA_RS05995 63039873aee4665088b5daa9457ecbdb 220 SMART SM00862 144 219 1.7E-19 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS05995 63039873aee4665088b5daa9457ecbdb 220 SUPERFAMILY SSF46894 127 219 1.59E-19 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS05995 63039873aee4665088b5daa9457ecbdb 220 SUPERFAMILY SSF52172 3 158 1.42E-32 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS05995 63039873aee4665088b5daa9457ecbdb 220 Pfam PF00072 Response regulator receiver domain 5 113 7.1E-19 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS05995 63039873aee4665088b5daa9457ecbdb 220 Gene3D G3DSA:1.10.10.10 130 220 1.2E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS05995 63039873aee4665088b5daa9457ecbdb 220 Pfam PF00486 Transcriptional regulatory protein, C terminal 144 219 1.6E-18 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS05995 63039873aee4665088b5daa9457ecbdb 220 Gene3D G3DSA:3.40.50.2300 1 129 8.4E-29 T 29-03-2018 SMALA_RS05995 63039873aee4665088b5daa9457ecbdb 220 SMART SM00448 3 113 2.8E-32 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS00415 7119235b37524bf9653849b2ae4e43a0 1636 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 397 516 1.5E-40 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS00415 7119235b37524bf9653849b2ae4e43a0 1636 SUPERFAMILY SSF52151 858 957 8.37E-53 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS00415 7119235b37524bf9653849b2ae4e43a0 1636 SUPERFAMILY SSF52151 664 798 8.37E-53 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS00415 7119235b37524bf9653849b2ae4e43a0 1636 SUPERFAMILY SSF47336 1559 1625 2.09E-17 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS00415 7119235b37524bf9653849b2ae4e43a0 1636 Gene3D G3DSA:3.40.47.10 136 401 3.0E-70 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS00415 7119235b37524bf9653849b2ae4e43a0 1636 SUPERFAMILY SSF51735 1287 1500 8.5E-36 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS00415 7119235b37524bf9653849b2ae4e43a0 1636 Gene3D G3DSA:3.40.50.720 1283 1508 5.2E-40 T 29-03-2018 SMALA_RS00415 7119235b37524bf9653849b2ae4e43a0 1636 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1586 1601 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS00415 7119235b37524bf9653849b2ae4e43a0 1636 SMART SM00825 Beta-ketoacyl synthase 143 569 4.6E-163 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS00415 7119235b37524bf9653849b2ae4e43a0 1636 Pfam PF08659 KR domain 1290 1463 5.2E-36 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS00415 7119235b37524bf9653849b2ae4e43a0 1636 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 142 389 6.9E-66 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS00415 7119235b37524bf9653849b2ae4e43a0 1636 SUPERFAMILY SSF53901 545 565 3.12E-81 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS00415 7119235b37524bf9653849b2ae4e43a0 1636 SUPERFAMILY SSF53901 142 257 3.12E-81 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS00415 7119235b37524bf9653849b2ae4e43a0 1636 SUPERFAMILY SSF53901 285 512 3.12E-81 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS00415 7119235b37524bf9653849b2ae4e43a0 1636 Gene3D G3DSA:3.40.366.10 663 808 5.3E-34 T 29-03-2018 SMALA_RS00415 7119235b37524bf9653849b2ae4e43a0 1636 SMART SM00823 Phosphopantetheine attachment site 1562 1631 2.5E-5 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS00415 7119235b37524bf9653849b2ae4e43a0 1636 SUPERFAMILY SSF55048 796 855 1.29E-7 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS00415 7119235b37524bf9653849b2ae4e43a0 1636 Gene3D G3DSA:3.30.70.250 809 851 1.7E-13 T 29-03-2018 SMALA_RS00415 7119235b37524bf9653849b2ae4e43a0 1636 Gene3D G3DSA:3.40.47.10 404 567 1.3E-52 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS00415 7119235b37524bf9653849b2ae4e43a0 1636 Gene3D G3DSA:3.40.366.10 852 964 2.3E-17 T 29-03-2018 SMALA_RS00415 7119235b37524bf9653849b2ae4e43a0 1636 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 667 980 1.4E-70 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS00415 7119235b37524bf9653849b2ae4e43a0 1636 Pfam PF00550 Phosphopantetheine attachment site 1564 1625 1.1E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS00415 7119235b37524bf9653849b2ae4e43a0 1636 SUPERFAMILY SSF51735 1040 1277 3.57E-17 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS00415 7119235b37524bf9653849b2ae4e43a0 1636 Pfam PF00698 Acyl transferase domain 665 964 4.4E-41 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS00415 7119235b37524bf9653849b2ae4e43a0 1636 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1290 1465 3.3E-31 T 29-03-2018 SMALA_RS00415 7119235b37524bf9653849b2ae4e43a0 1636 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 524 627 3.2E-14 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS00415 7119235b37524bf9653849b2ae4e43a0 1636 Gene3D G3DSA:1.10.1200.10 1557 1626 3.1E-21 T 29-03-2018 SMALA_RS32600 3555c90fd50ab31256a23f7bbbc0ebb1 435 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 23 45 - T 29-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 SMALA_RS32600 3555c90fd50ab31256a23f7bbbc0ebb1 435 SUPERFAMILY SSF56112 13 261 1.17E-62 T 29-03-2018 IPR011009 Protein kinase-like domain SMALA_RS32600 3555c90fd50ab31256a23f7bbbc0ebb1 435 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 135 147 - T 29-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMALA_RS32600 3555c90fd50ab31256a23f7bbbc0ebb1 435 PIRSF PIRSF000654 11 277 7.0E-18 T 29-03-2018 SMALA_RS32600 3555c90fd50ab31256a23f7bbbc0ebb1 435 SMART SM00220 17 269 5.0E-46 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMALA_RS32600 3555c90fd50ab31256a23f7bbbc0ebb1 435 Pfam PF00069 Protein kinase domain 18 261 5.0E-40 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMALA_RS32600 3555c90fd50ab31256a23f7bbbc0ebb1 435 Gene3D G3DSA:3.30.200.20 2 97 1.1E-16 T 29-03-2018 SMALA_RS32600 3555c90fd50ab31256a23f7bbbc0ebb1 435 Gene3D G3DSA:1.10.510.10 98 357 1.8E-41 T 29-03-2018 SMALA_RS09360 4ca2c6c4771639f4c7742165fffd63bc 399 Gene3D G3DSA:3.20.20.80 49 194 4.2E-8 T 29-03-2018 SMALA_RS09360 4ca2c6c4771639f4c7742165fffd63bc 399 Gene3D G3DSA:3.20.20.120 331 399 0.11 T 29-03-2018 IPR029065 Enolase C-terminal domain-like SMALA_RS05450 79a01da8de7a1d5468ebaa4e3090c3d8 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 114 130 9.1E-23 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS05450 79a01da8de7a1d5468ebaa4e3090c3d8 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 9.1E-23 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS05450 79a01da8de7a1d5468ebaa4e3090c3d8 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 159 9.1E-23 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS05450 79a01da8de7a1d5468ebaa4e3090c3d8 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 67 78 9.1E-23 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS05450 79a01da8de7a1d5468ebaa4e3090c3d8 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 178 9.1E-23 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS05450 79a01da8de7a1d5468ebaa4e3090c3d8 249 Pfam PF00106 short chain dehydrogenase 2 179 1.5E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS05450 79a01da8de7a1d5468ebaa4e3090c3d8 249 Gene3D G3DSA:3.40.50.720 1 249 1.6E-55 T 29-03-2018 SMALA_RS05450 79a01da8de7a1d5468ebaa4e3090c3d8 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 120 128 1.6E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS05450 79a01da8de7a1d5468ebaa4e3090c3d8 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 159 1.6E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS05450 79a01da8de7a1d5468ebaa4e3090c3d8 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 67 78 1.6E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS05450 79a01da8de7a1d5468ebaa4e3090c3d8 249 SUPERFAMILY SSF51735 1 239 9.32E-58 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS03570 420c07e4534d173bca74aeab75eddffc 236 Gene3D G3DSA:1.10.10.10 10 90 2.1E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS03570 420c07e4534d173bca74aeab75eddffc 236 SMART SM00345 30 88 3.7E-12 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS03570 420c07e4534d173bca74aeab75eddffc 236 SUPERFAMILY SSF48008 93 228 2.3E-26 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS03570 420c07e4534d173bca74aeab75eddffc 236 Gene3D G3DSA:1.20.120.530 91 236 1.4E-23 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS03570 420c07e4534d173bca74aeab75eddffc 236 SMART SM00895 98 220 4.5E-17 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS03570 420c07e4534d173bca74aeab75eddffc 236 Pfam PF07729 FCD domain 98 219 1.1E-14 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS03570 420c07e4534d173bca74aeab75eddffc 236 SUPERFAMILY SSF46785 22 92 3.86E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS03570 420c07e4534d173bca74aeab75eddffc 236 Pfam PF00392 Bacterial regulatory proteins, gntR family 26 88 1.6E-14 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS32510 d17394672ee401278bdace2351ae393f 476 Gene3D G3DSA:1.10.40.30 385 442 3.3E-25 T 29-03-2018 SMALA_RS32510 d17394672ee401278bdace2351ae393f 476 Gene3D G3DSA:1.10.275.10 10 115 3.9E-34 T 29-03-2018 IPR024083 Fumarase/histidase, N-terminal SMALA_RS32510 d17394672ee401278bdace2351ae393f 476 ProSitePatterns PS00163 Fumarate lyases signature. 285 294 - T 29-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 SMALA_RS32510 d17394672ee401278bdace2351ae393f 476 Pfam PF00206 Lyase 14 310 2.1E-64 T 29-03-2018 IPR022761 Fumarate lyase, N-terminal SMALA_RS32510 d17394672ee401278bdace2351ae393f 476 Gene3D G3DSA:1.20.200.10 116 384 7.6E-93 T 29-03-2018 SMALA_RS32510 d17394672ee401278bdace2351ae393f 476 Pfam PF14698 Argininosuccinate lyase C-terminal 373 438 4.4E-22 T 29-03-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SMALA_RS32510 d17394672ee401278bdace2351ae393f 476 PRINTS PR00145 Argininosuccinate lyase family signature 110 132 8.4E-54 T 29-03-2018 SMALA_RS32510 d17394672ee401278bdace2351ae393f 476 PRINTS PR00145 Argininosuccinate lyase family signature 285 301 8.4E-54 T 29-03-2018 SMALA_RS32510 d17394672ee401278bdace2351ae393f 476 PRINTS PR00145 Argininosuccinate lyase family signature 241 265 8.4E-54 T 29-03-2018 SMALA_RS32510 d17394672ee401278bdace2351ae393f 476 PRINTS PR00145 Argininosuccinate lyase family signature 202 218 8.4E-54 T 29-03-2018 SMALA_RS32510 d17394672ee401278bdace2351ae393f 476 PRINTS PR00145 Argininosuccinate lyase family signature 151 171 8.4E-54 T 29-03-2018 SMALA_RS32510 d17394672ee401278bdace2351ae393f 476 PRINTS PR00145 Argininosuccinate lyase family signature 320 339 8.4E-54 T 29-03-2018 SMALA_RS32510 d17394672ee401278bdace2351ae393f 476 PRINTS PR00149 Fumarate lyase superfamily signature 241 268 4.5E-26 T 29-03-2018 IPR000362 Fumarate lyase family SMALA_RS32510 d17394672ee401278bdace2351ae393f 476 PRINTS PR00149 Fumarate lyase superfamily signature 156 174 4.5E-26 T 29-03-2018 IPR000362 Fumarate lyase family SMALA_RS32510 d17394672ee401278bdace2351ae393f 476 PRINTS PR00149 Fumarate lyase superfamily signature 285 301 4.5E-26 T 29-03-2018 IPR000362 Fumarate lyase family SMALA_RS32510 d17394672ee401278bdace2351ae393f 476 PRINTS PR00149 Fumarate lyase superfamily signature 111 129 4.5E-26 T 29-03-2018 IPR000362 Fumarate lyase family SMALA_RS32510 d17394672ee401278bdace2351ae393f 476 TIGRFAM TIGR00838 argH: argininosuccinate lyase 11 465 3.9E-181 T 29-03-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SMALA_RS32510 d17394672ee401278bdace2351ae393f 476 Hamap MF_00006 Argininosuccinate lyase [argH]. 10 463 40.818 T 29-03-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SMALA_RS32510 d17394672ee401278bdace2351ae393f 476 SUPERFAMILY SSF48557 14 465 3.46E-137 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 SMALA_RS42850 2d0b210d496bb6acee25ee254e0511e3 868 Pfam PF00391 PEP-utilising enzyme, mobile domain 791 862 9.2E-20 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 SMALA_RS42850 2d0b210d496bb6acee25ee254e0511e3 868 Gene3D G3DSA:3.30.1490.20 1 184 3.9E-57 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SMALA_RS42850 2d0b210d496bb6acee25ee254e0511e3 868 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 18 316 3.2E-88 T 29-03-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 SMALA_RS42850 2d0b210d496bb6acee25ee254e0511e3 868 SUPERFAMILY SSF56059 2 343 1.18E-93 T 29-03-2018 SMALA_RS42850 2d0b210d496bb6acee25ee254e0511e3 868 Gene3D G3DSA:3.50.30.10 766 868 4.2E-29 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 SMALA_RS42850 2d0b210d496bb6acee25ee254e0511e3 868 SUPERFAMILY SSF52009 766 866 2.88E-25 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 SMALA_RS42850 2d0b210d496bb6acee25ee254e0511e3 868 Gene3D G3DSA:3.30.470.20 185 315 1.2E-42 T 29-03-2018 SMALA_RS37005 81ed73f055dd6ebdbf8390ec3a6245a1 186 Pfam PF09684 Phage tail protein (Tail_P2_I) 33 136 4.8E-14 T 29-03-2018 IPR006521 Tail protein I SMALA_RS37005 81ed73f055dd6ebdbf8390ec3a6245a1 186 TIGRFAM TIGR02242 tail_TIGR02242: phage tail protein domain 16 124 8.9E-30 T 29-03-2018 IPR011748 Uncharacterised protein family, phage tail-like SMALA_RS37005 81ed73f055dd6ebdbf8390ec3a6245a1 186 TIGRFAM TIGR01634 tail_P2_I: phage tail protein I 35 169 4.8E-8 T 29-03-2018 IPR006521 Tail protein I SMALA_RS10885 f53e340d38b7a763cb2034a92b90f340 367 ProSitePatterns PS00356 LacI-type HTH domain signature. 23 41 - T 29-03-2018 SMALA_RS10885 f53e340d38b7a763cb2034a92b90f340 367 Pfam PF13377 Periplasmic binding protein-like domain 189 351 8.5E-37 T 29-03-2018 SMALA_RS10885 f53e340d38b7a763cb2034a92b90f340 367 SMART SM00354 20 87 2.2E-23 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS10885 f53e340d38b7a763cb2034a92b90f340 367 Pfam PF00356 Bacterial regulatory proteins, lacI family 23 65 1.9E-14 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS10885 f53e340d38b7a763cb2034a92b90f340 367 Gene3D G3DSA:1.10.10.10 12 34 0.0015 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS10885 f53e340d38b7a763cb2034a92b90f340 367 Gene3D G3DSA:3.40.50.2300 68 187 6.2E-26 T 29-03-2018 SMALA_RS10885 f53e340d38b7a763cb2034a92b90f340 367 SUPERFAMILY SSF53822 77 353 6.28E-66 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SMALA_RS10885 f53e340d38b7a763cb2034a92b90f340 367 SUPERFAMILY SSF47413 21 67 6.49E-12 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS10885 f53e340d38b7a763cb2034a92b90f340 367 Gene3D G3DSA:3.40.50.2300 188 354 9.6E-47 T 29-03-2018 SMALA_RS10885 f53e340d38b7a763cb2034a92b90f340 367 Gene3D G3DSA:1.10.260.40 35 67 2.0E-14 T 29-03-2018 SMALA_RS10885 f53e340d38b7a763cb2034a92b90f340 367 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 22 32 8.0E-5 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS10885 f53e340d38b7a763cb2034a92b90f340 367 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 32 42 8.0E-5 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS00530 bd4b2cff3ccdb918a7e18d33c197ca9a 297 SUPERFAMILY SSF81301 51 116 1.26E-5 T 29-03-2018 SMALA_RS00530 bd4b2cff3ccdb918a7e18d33c197ca9a 297 Gene3D G3DSA:3.30.460.10 37 209 2.2E-7 T 29-03-2018 SMALA_RS00530 bd4b2cff3ccdb918a7e18d33c197ca9a 297 Pfam PF13427 Domain of unknown function (DUF4111) 187 285 1.2E-7 T 29-03-2018 IPR025184 Domain of unknown function DUF4111 SMALA_RS06050 3dfcde226cf573f5c27d23bc7a018d6d 262 SMART SM00345 25 84 3.1E-23 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS06050 3dfcde226cf573f5c27d23bc7a018d6d 262 Gene3D G3DSA:1.10.10.10 9 86 2.4E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS06050 3dfcde226cf573f5c27d23bc7a018d6d 262 SMART SM00895 108 229 8.3E-24 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS06050 3dfcde226cf573f5c27d23bc7a018d6d 262 SUPERFAMILY SSF48008 105 232 1.73E-29 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS06050 3dfcde226cf573f5c27d23bc7a018d6d 262 Pfam PF00392 Bacterial regulatory proteins, gntR family 21 84 7.3E-23 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS06050 3dfcde226cf573f5c27d23bc7a018d6d 262 Pfam PF07729 FCD domain 108 227 3.2E-25 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS06050 3dfcde226cf573f5c27d23bc7a018d6d 262 SUPERFAMILY SSF46785 19 88 2.54E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS06050 3dfcde226cf573f5c27d23bc7a018d6d 262 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 44 58 4.0E-9 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS06050 3dfcde226cf573f5c27d23bc7a018d6d 262 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 58 74 4.0E-9 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS06050 3dfcde226cf573f5c27d23bc7a018d6d 262 Gene3D G3DSA:1.20.120.530 103 240 1.6E-27 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS02850 b2edc4128c3a7afaca650d283fbbac0d 548 Gene3D G3DSA:2.60.40.10 340 439 9.2E-17 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS02850 b2edc4128c3a7afaca650d283fbbac0d 548 SMART SM00637 445 545 5.7E-41 T 29-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 SMALA_RS02850 b2edc4128c3a7afaca650d283fbbac0d 548 Gene3D G3DSA:3.20.20.80 23 336 3.8E-50 T 29-03-2018 SMALA_RS02850 b2edc4128c3a7afaca650d283fbbac0d 548 Gene3D G3DSA:2.60.40.290 440 545 5.2E-33 T 29-03-2018 SMALA_RS02850 b2edc4128c3a7afaca650d283fbbac0d 548 Pfam PF00553 Cellulose binding domain 445 545 3.4E-28 T 29-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 SMALA_RS02850 b2edc4128c3a7afaca650d283fbbac0d 548 SUPERFAMILY SSF49384 441 546 3.42E-30 T 29-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 SMALA_RS02850 b2edc4128c3a7afaca650d283fbbac0d 548 SUPERFAMILY SSF49265 345 437 2.13E-16 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 SMALA_RS02850 b2edc4128c3a7afaca650d283fbbac0d 548 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 51 296 3.3E-33 T 29-03-2018 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 SMALA_RS02850 b2edc4128c3a7afaca650d283fbbac0d 548 Pfam PF00041 Fibronectin type III domain 348 424 9.3E-9 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 SMALA_RS02850 b2edc4128c3a7afaca650d283fbbac0d 548 SMART SM00060 347 424 3.8E-9 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 SMALA_RS02850 b2edc4128c3a7afaca650d283fbbac0d 548 SUPERFAMILY SSF51445 41 335 9.05E-68 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS15900 627fab4adcfede05e961a207f2642727 368 SUPERFAMILY SSF53448 12 250 7.27E-67 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS15900 627fab4adcfede05e961a207f2642727 368 SUPERFAMILY SSF53448 287 336 7.27E-67 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS15900 627fab4adcfede05e961a207f2642727 368 Gene3D G3DSA:3.90.550.10 11 255 1.2E-56 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS15900 627fab4adcfede05e961a207f2642727 368 Gene3D G3DSA:2.160.10.10 259 363 1.1E-16 T 29-03-2018 SMALA_RS15900 627fab4adcfede05e961a207f2642727 368 Pfam PF00483 Nucleotidyl transferase 12 244 1.9E-44 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 SMALA_RS00485 f3a83d726fc6f6d513f422c54b4ac686 492 Gene3D G3DSA:3.90.100.10 405 491 2.6E-23 T 29-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 SMALA_RS00485 f3a83d726fc6f6d513f422c54b4ac686 492 SUPERFAMILY SSF55904 341 486 1.23E-28 T 29-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 SMALA_RS00485 f3a83d726fc6f6d513f422c54b4ac686 492 Gene3D G3DSA:3.40.640.10 6 284 2.5E-46 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS00485 f3a83d726fc6f6d513f422c54b4ac686 492 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 7 300 5.9E-47 T 29-03-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 SMALA_RS00485 f3a83d726fc6f6d513f422c54b4ac686 492 Gene3D G3DSA:3.90.1150.10 305 404 3.3E-14 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS00485 f3a83d726fc6f6d513f422c54b4ac686 492 SUPERFAMILY SSF53383 7 385 6.45E-71 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS00485 f3a83d726fc6f6d513f422c54b4ac686 492 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 418 470 6.5E-13 T 29-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 SMALA_RS23955 d7bc1650e284a18b94041ba2eb4dc7ea 298 Gene3D G3DSA:3.40.50.150 26 238 4.8E-47 T 29-03-2018 SMALA_RS23955 d7bc1650e284a18b94041ba2eb4dc7ea 298 SMART SM00650 50 224 3.3E-69 T 29-03-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 SMALA_RS23955 d7bc1650e284a18b94041ba2eb4dc7ea 298 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 34 293 9.7E-71 T 29-03-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 SMALA_RS23955 d7bc1650e284a18b94041ba2eb4dc7ea 298 Pfam PF00398 Ribosomal RNA adenine dimethylase 38 292 8.7E-42 T 29-03-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm SMALA_RS23955 d7bc1650e284a18b94041ba2eb4dc7ea 298 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 34 296 48.407 T 29-03-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 SMALA_RS23955 d7bc1650e284a18b94041ba2eb4dc7ea 298 SUPERFAMILY SSF53335 33 293 4.96E-63 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS23955 d7bc1650e284a18b94041ba2eb4dc7ea 298 Gene3D G3DSA:1.10.8.100 239 294 5.9E-19 T 29-03-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 SMALA_RS23955 d7bc1650e284a18b94041ba2eb4dc7ea 298 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 66 93 - T 29-03-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 SMALA_RS34750 a721b178fdfc976aa8c953292f564cf7 289 SMART SM00530 15 70 6.9E-10 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS34750 a721b178fdfc976aa8c953292f564cf7 289 Pfam PF13560 Helix-turn-helix domain 12 73 8.3E-16 T 29-03-2018 SMALA_RS34750 a721b178fdfc976aa8c953292f564cf7 289 SUPERFAMILY SSF47413 8 65 2.33E-10 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS34750 a721b178fdfc976aa8c953292f564cf7 289 Gene3D G3DSA:1.10.260.40 5 74 1.5E-14 T 29-03-2018 SMALA_RS27990 666eedea650d84bcdcaa1270dcdb0c80 749 Pfam PF00271 Helicase conserved C-terminal domain 565 636 1.8E-18 T 29-03-2018 IPR001650 Helicase, C-terminal SMALA_RS27990 666eedea650d84bcdcaa1270dcdb0c80 749 SUPERFAMILY SSF52540 191 476 9.27E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS27990 666eedea650d84bcdcaa1270dcdb0c80 749 Gene3D G3DSA:3.40.50.300 487 678 6.5E-30 T 29-03-2018 SMALA_RS27990 666eedea650d84bcdcaa1270dcdb0c80 749 Gene3D G3DSA:3.40.50.300 255 480 3.4E-35 T 29-03-2018 SMALA_RS27990 666eedea650d84bcdcaa1270dcdb0c80 749 SMART SM00487 270 495 4.0E-29 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain SMALA_RS27990 666eedea650d84bcdcaa1270dcdb0c80 749 Pfam PF01336 OB-fold nucleic acid binding domain 58 134 6.2E-9 T 29-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 SMALA_RS27990 666eedea650d84bcdcaa1270dcdb0c80 749 Pfam PF00270 DEAD/DEAH box helicase 296 459 2.0E-14 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 SMALA_RS27990 666eedea650d84bcdcaa1270dcdb0c80 749 SUPERFAMILY SSF52540 295 347 2.49E-40 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS27990 666eedea650d84bcdcaa1270dcdb0c80 749 SUPERFAMILY SSF52540 555 693 2.49E-40 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS27990 666eedea650d84bcdcaa1270dcdb0c80 749 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 25 714 6.3E-199 T 29-03-2018 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 SMALA_RS27990 666eedea650d84bcdcaa1270dcdb0c80 749 Gene3D G3DSA:2.40.50.140 43 142 7.3E-22 T 29-03-2018 SMALA_RS27990 666eedea650d84bcdcaa1270dcdb0c80 749 SUPERFAMILY SSF50249 12 176 1.43E-26 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMALA_RS27990 666eedea650d84bcdcaa1270dcdb0c80 749 SMART SM00490 552 637 6.3E-23 T 29-03-2018 IPR001650 Helicase, C-terminal SMALA_RS33300 98fdc59ae03dd4c439c9bbda1c4a6a9b 425 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 16 209 5.9E-84 T 29-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 SMALA_RS33300 98fdc59ae03dd4c439c9bbda1c4a6a9b 425 SUPERFAMILY SSF55821 10 211 1.47E-81 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain SMALA_RS33300 98fdc59ae03dd4c439c9bbda1c4a6a9b 425 Hamap MF_01283 Riboflavin biosynthesis protein RibBA [ribBA]. 11 406 52.675 T 29-03-2018 IPR016299 Riboflavin biosynthesis protein RibBA GO:0009231 KEGG: 00740+3.5.4.25+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7539 SMALA_RS33300 98fdc59ae03dd4c439c9bbda1c4a6a9b 425 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 219 407 3.0E-73 T 29-03-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 SMALA_RS33300 98fdc59ae03dd4c439c9bbda1c4a6a9b 425 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 215 410 40.211 T 29-03-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 SMALA_RS33300 98fdc59ae03dd4c439c9bbda1c4a6a9b 425 Pfam PF00925 GTP cyclohydrolase II 219 383 1.3E-66 T 29-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 SMALA_RS33300 98fdc59ae03dd4c439c9bbda1c4a6a9b 425 SUPERFAMILY SSF142695 216 386 4.18E-64 T 29-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 SMALA_RS33300 98fdc59ae03dd4c439c9bbda1c4a6a9b 425 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 10 214 38.88 T 29-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 SMALA_RS33300 98fdc59ae03dd4c439c9bbda1c4a6a9b 425 PIRSF PIRSF001259 11 415 2.0E-171 T 29-03-2018 SMALA_RS33300 98fdc59ae03dd4c439c9bbda1c4a6a9b 425 Gene3D G3DSA:3.90.870.10 2 223 2.5E-95 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain SMALA_RS33300 98fdc59ae03dd4c439c9bbda1c4a6a9b 425 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 12 210 6.2E-74 T 29-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 SMALA_RS22945 5e671cd532bc3faaca485869e5a8630e 203 SUPERFAMILY SSF46894 128 202 2.79E-20 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS22945 5e671cd532bc3faaca485869e5a8630e 203 Gene3D G3DSA:1.10.10.10 140 202 5.4E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS22945 5e671cd532bc3faaca485869e5a8630e 203 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 142 156 3.2E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS22945 5e671cd532bc3faaca485869e5a8630e 203 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 172 3.2E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS22945 5e671cd532bc3faaca485869e5a8630e 203 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 184 3.2E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS22945 5e671cd532bc3faaca485869e5a8630e 203 ProSitePatterns PS00622 LuxR-type HTH domain signature. 156 183 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS22945 5e671cd532bc3faaca485869e5a8630e 203 SMART SM00448 2 115 4.9E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS22945 5e671cd532bc3faaca485869e5a8630e 203 Pfam PF00072 Response regulator receiver domain 4 115 1.1E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS22945 5e671cd532bc3faaca485869e5a8630e 203 Gene3D G3DSA:3.40.50.2300 1 139 3.4E-31 T 29-03-2018 SMALA_RS22945 5e671cd532bc3faaca485869e5a8630e 203 SUPERFAMILY SSF52172 1 127 1.37E-29 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS22945 5e671cd532bc3faaca485869e5a8630e 203 SMART SM00421 139 196 1.2E-22 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS22945 5e671cd532bc3faaca485869e5a8630e 203 Pfam PF00196 Bacterial regulatory proteins, luxR family 141 194 6.6E-18 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS19565 e670fe077a5627db719aa7a1a1a3b659 446 PIRSF PIRSF006603 14 446 9.4E-61 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 SMALA_RS19565 e670fe077a5627db719aa7a1a1a3b659 446 TIGRFAM TIGR00797 matE: MATE efflux family protein 25 415 9.9E-98 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 SMALA_RS19565 e670fe077a5627db719aa7a1a1a3b659 446 Pfam PF01554 MatE 243 401 2.3E-22 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 SMALA_RS19565 e670fe077a5627db719aa7a1a1a3b659 446 Pfam PF01554 MatE 25 184 7.5E-26 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 SMALA_RS09195 95a91dd262da803ab9080c6011b2c459 483 SUPERFAMILY SSF52540 6 216 1.38E-41 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS09195 95a91dd262da803ab9080c6011b2c459 483 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 7 210 2.3E-21 T 29-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain SMALA_RS09195 95a91dd262da803ab9080c6011b2c459 483 TIGRFAM TIGR00379 cobB: cobyrinic acid a,c-diamide synthase 6 476 8.3E-113 T 29-03-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 SMALA_RS09195 95a91dd262da803ab9080c6011b2c459 483 Gene3D G3DSA:3.40.50.880 208 434 1.1E-27 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS09195 95a91dd262da803ab9080c6011b2c459 483 Gene3D G3DSA:3.40.50.300 2 207 6.1E-39 T 29-03-2018 SMALA_RS09195 95a91dd262da803ab9080c6011b2c459 483 Hamap MF_00027 Cobyrinate a,c-diamide synthase [cbiA]. 4 468 39.897 T 29-03-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 SMALA_RS09195 95a91dd262da803ab9080c6011b2c459 483 SUPERFAMILY SSF52317 283 478 5.73E-30 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS09195 95a91dd262da803ab9080c6011b2c459 483 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 285 466 3.2E-22 T 29-03-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 SMALA_RS17370 cefdbba1bd9ebbc7c443e987f1467623 127 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 29-03-2018 IPR019844 Cold-shock conserved site SMALA_RS17370 cefdbba1bd9ebbc7c443e987f1467623 127 PRINTS PR00050 Cold shock protein signature 38 56 4.0E-14 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMALA_RS17370 cefdbba1bd9ebbc7c443e987f1467623 127 PRINTS PR00050 Cold shock protein signature 24 33 4.0E-14 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMALA_RS17370 cefdbba1bd9ebbc7c443e987f1467623 127 PRINTS PR00050 Cold shock protein signature 4 19 4.0E-14 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMALA_RS17370 cefdbba1bd9ebbc7c443e987f1467623 127 Gene3D G3DSA:2.40.50.140 2 74 9.1E-22 T 29-03-2018 SMALA_RS17370 cefdbba1bd9ebbc7c443e987f1467623 127 SMART SM00357 3 65 1.0E-21 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 SMALA_RS17370 cefdbba1bd9ebbc7c443e987f1467623 127 SUPERFAMILY SSF50249 2 65 6.12E-19 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMALA_RS17370 cefdbba1bd9ebbc7c443e987f1467623 127 Pfam PF00313 'Cold-shock' DNA-binding domain 3 63 3.0E-21 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMALA_RS21420 791181f5df41e505f9c298d37e267244 251 Pfam PF00440 Bacterial regulatory proteins, tetR family 37 80 3.1E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS21420 791181f5df41e505f9c298d37e267244 251 SUPERFAMILY SSF46689 27 86 2.24E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS21420 791181f5df41e505f9c298d37e267244 251 Gene3D G3DSA:1.10.357.10 86 249 2.2E-35 T 29-03-2018 SMALA_RS21420 791181f5df41e505f9c298d37e267244 251 Gene3D G3DSA:1.10.10.60 12 85 6.0E-15 T 29-03-2018 SMALA_RS21420 791181f5df41e505f9c298d37e267244 251 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 96 246 9.0E-21 T 29-03-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 SMALA_RS21420 791181f5df41e505f9c298d37e267244 251 SUPERFAMILY SSF48498 101 248 2.45E-25 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2770 2785 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 Gene3D G3DSA:1.10.1200.10 5320 5423 6.4E-17 T 29-03-2018 SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 SUPERFAMILY SSF47336 5343 5426 1.44E-18 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 3210 3328 4.9E-15 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1492 1596 1.6E-10 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 4252 4370 1.6E-13 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 Gene3D G3DSA:3.40.366.10 3550 3670 1.1E-32 T 29-03-2018 SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 SUPERFAMILY SSF55048 1766 1831 3.66E-12 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1279 1295 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 SUPERFAMILY SSF53901 3872 4246 4.62E-100 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 Gene3D G3DSA:3.40.366.10 4586 4706 2.9E-27 T 29-03-2018 SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 SUPERFAMILY SSF56801 8 508 1.31E-142 T 29-03-2018 SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 SMART SM00825 Beta-ketoacyl synthase 2836 3260 1.1E-225 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 SMART SM00825 Beta-ketoacyl synthase 3876 4302 7.6E-226 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 SMART SM00825 Beta-ketoacyl synthase 1115 1542 5.2E-222 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 Gene3D G3DSA:2.30.38.10 328 410 5.0E-29 T 29-03-2018 SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 SUPERFAMILY SSF51735 4828 5053 8.07E-42 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2458 2638 2.5E-55 T 29-03-2018 SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5065 5244 1.2E-28 T 29-03-2018 SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 757 922 1.6E-8 T 29-03-2018 SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 SUPERFAMILY SSF51735 5061 5326 4.93E-38 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 Pfam PF00698 Acyl transferase domain 4406 4723 1.0E-52 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 Pfam PF00698 Acyl transferase domain 3363 3687 3.4E-53 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 Pfam PF00698 Acyl transferase domain 1641 1959 6.3E-85 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 Gene3D G3DSA:1.10.1200.10 3768 3861 8.2E-19 T 29-03-2018 SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 SUPERFAMILY SSF55048 3495 3559 8.76E-13 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 SUPERFAMILY SSF52151 4595 4691 1.41E-67 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 SUPERFAMILY SSF52151 4403 4534 1.41E-67 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 Gene3D G3DSA:3.40.50.980 177 327 3.5E-38 T 29-03-2018 SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 Gene3D G3DSA:3.40.47.10 1381 1540 1.2E-60 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 Gene3D G3DSA:3.40.47.10 4139 4300 2.3E-60 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 Gene3D G3DSA:3.40.47.10 3099 3258 2.5E-64 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 SUPERFAMILY SSF51735 2289 2445 2.6E-21 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 Pfam PF00550 Phosphopantetheine attachment site 5366 5418 4.3E-9 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 Pfam PF00550 Phosphopantetheine attachment site 1009 1072 6.5E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 Pfam PF00550 Phosphopantetheine attachment site 3786 3851 3.7E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 Pfam PF00550 Phosphopantetheine attachment site 2748 2811 2.4E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 2997 3013 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 SUPERFAMILY SSF52151 3560 3654 3.92E-70 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 SUPERFAMILY SSF52151 3359 3497 3.92E-70 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3810 3825 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 SUPERFAMILY SSF53901 2832 3206 2.22E-101 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 SMART SM00823 Phosphopantetheine attachment site 1007 1079 1.5E-26 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 SMART SM00823 Phosphopantetheine attachment site 5350 5422 3.4E-25 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 SMART SM00823 Phosphopantetheine attachment site 2743 2815 2.4E-29 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 SMART SM00823 Phosphopantetheine attachment site 3783 3855 9.9E-28 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 Gene3D G3DSA:3.40.47.10 3869 4136 5.0E-86 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 Gene3D G3DSA:3.40.47.10 2835 3096 1.9E-85 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 Gene3D G3DSA:3.40.47.10 1111 1378 7.4E-84 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 SUPERFAMILY SSF47336 1004 1128 3.01E-20 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 Gene3D G3DSA:1.10.1200.10 2736 2834 7.5E-18 T 29-03-2018 SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 Gene3D G3DSA:1.10.1200.10 999 1110 2.0E-17 T 29-03-2018 SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 Gene3D G3DSA:3.40.366.10 3356 3506 5.6E-44 T 29-03-2018 SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 SUPERFAMILY SSF55048 4533 4594 4.05E-10 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 SUPERFAMILY SSF51735 2457 2710 9.94E-42 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 SUPERFAMILY SSF53901 1111 1234 8.92E-100 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 SUPERFAMILY SSF53901 1262 1479 8.92E-100 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 Pfam PF00501 AMP-binding enzyme 15 417 3.9E-101 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 4037 4053 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 SMART SM01294 2744 2811 5.1E-5 T 29-03-2018 SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 SMART SM01294 5351 5418 5.7E-6 T 29-03-2018 SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 SMART SM01294 1008 1075 5.1E-5 T 29-03-2018 SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 Gene3D G3DSA:3.10.129.10 2011 2139 4.8E-8 T 29-03-2018 SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 ProSitePatterns PS00012 Phosphopantetheine attachment site. 5377 5392 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 SUPERFAMILY SSF47336 2736 2849 1.07E-21 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 Gene3D G3DSA:3.30.70.250 4543 4585 8.8E-17 T 29-03-2018 SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 Gene3D G3DSA:3.30.70.250 3507 3549 7.7E-20 T 29-03-2018 SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 Gene3D G3DSA:3.30.70.250 1774 1825 8.7E-16 T 29-03-2018 SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 SUPERFAMILY SSF52151 1832 1924 7.85E-64 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 SUPERFAMILY SSF52151 1638 1767 7.85E-64 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 4406 4705 3.7E-112 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 3363 3669 1.1E-117 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1642 1941 3.0E-114 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 Gene3D G3DSA:3.40.50.980 7 176 1.3E-36 T 29-03-2018 SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1113 1366 1.8E-92 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3874 4124 1.0E-90 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2835 3084 1.4E-89 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 Gene3D G3DSA:3.40.366.10 1826 1948 2.5E-22 T 29-03-2018 SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1374 1489 8.4E-43 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 3092 3207 1.0E-45 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 4132 4249 3.0E-42 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 SUPERFAMILY SSF51735 520 726 5.12E-26 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 Pfam PF13193 AMP-binding enzyme C-terminal domain 426 500 7.2E-15 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 SUPERFAMILY SSF47336 3778 3889 2.36E-23 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 Pfam PF08659 KR domain 5065 5242 5.5E-46 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 Pfam PF08659 KR domain 757 920 9.2E-19 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 Pfam PF08659 KR domain 2458 2636 7.0E-56 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 ProSitePatterns PS00455 Putative AMP-binding domain signature. 170 181 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 Gene3D G3DSA:3.30.300.30 412 513 6.0E-23 T 29-03-2018 SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 Gene3D G3DSA:3.40.366.10 4403 4542 5.1E-38 T 29-03-2018 SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 Gene3D G3DSA:3.40.366.10 1638 1773 2.4E-38 T 29-03-2018 SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 SMART SM00826 2009 2175 1.6E-75 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 Pfam PF14765 Polyketide synthase dehydratase 2009 2281 6.3E-46 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 SUPERFAMILY SSF51735 755 963 4.49E-18 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 Gene3D G3DSA:3.40.50.720 5057 5317 3.4E-45 T 29-03-2018 SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 Gene3D G3DSA:3.40.50.720 2450 2709 1.9E-44 T 29-03-2018 SMALA_RS02365 1cdcee97fb76c2327d719a71bce052f6 5503 Gene3D G3DSA:3.40.50.720 749 974 8.3E-19 T 29-03-2018 SMALA_RS00235 64a1978a88a4602f5abf12547c1c8226 251 SUPERFAMILY SSF46785 5 78 2.22E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS00235 64a1978a88a4602f5abf12547c1c8226 251 Gene3D G3DSA:1.10.10.10 3 75 5.2E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS00235 64a1978a88a4602f5abf12547c1c8226 251 SMART SM00895 98 224 2.1E-24 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS00235 64a1978a88a4602f5abf12547c1c8226 251 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 8.4E-9 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS00235 64a1978a88a4602f5abf12547c1c8226 251 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 8.4E-9 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS00235 64a1978a88a4602f5abf12547c1c8226 251 Pfam PF07729 FCD domain 98 223 6.3E-25 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS00235 64a1978a88a4602f5abf12547c1c8226 251 SMART SM00345 15 74 1.3E-18 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS00235 64a1978a88a4602f5abf12547c1c8226 251 Gene3D G3DSA:1.20.120.530 83 243 7.0E-30 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS00235 64a1978a88a4602f5abf12547c1c8226 251 SUPERFAMILY SSF48008 95 231 8.63E-30 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS00235 64a1978a88a4602f5abf12547c1c8226 251 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 74 2.4E-20 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS09965 2e52748286c9eb5147e1ca11e0d2e2ef 269 Gene3D G3DSA:3.20.20.70 1 264 3.7E-67 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS09965 2e52748286c9eb5147e1ca11e0d2e2ef 269 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 51 68 - T 29-03-2018 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 SMALA_RS09965 2e52748286c9eb5147e1ca11e0d2e2ef 269 SUPERFAMILY SSF51366 12 257 5.06E-77 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 SMALA_RS09965 2e52748286c9eb5147e1ca11e0d2e2ef 269 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 2 257 33.766 T 29-03-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 SMALA_RS09965 2e52748286c9eb5147e1ca11e0d2e2ef 269 Pfam PF00218 Indole-3-glycerol phosphate synthase 4 255 1.3E-80 T 29-03-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 SMALA_RS09965 2e52748286c9eb5147e1ca11e0d2e2ef 269 Hamap MF_00134_A Indole-3-glycerol phosphate synthase [trpC]. 34 253 29.583 T 29-03-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 SMALA_RS03455 16943d490405194703feae9a77daee05 149 SUPERFAMILY SSF50249 12 124 1.34E-14 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMALA_RS03455 16943d490405194703feae9a77daee05 149 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 54 124 6.2E-7 T 29-03-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal SMALA_RS03455 16943d490405194703feae9a77daee05 149 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 19 53 4.7E-8 T 29-03-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal SMALA_RS03455 16943d490405194703feae9a77daee05 149 Gene3D G3DSA:2.40.50.140 58 124 4.9E-6 T 29-03-2018 SMALA_RS33705 378cefb2c4206d95cf4f248689baf069 608 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 97 584 16.684 T 29-03-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 SMALA_RS33705 378cefb2c4206d95cf4f248689baf069 608 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 149 546 6.6E-74 T 29-03-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 SMALA_RS33705 378cefb2c4206d95cf4f248689baf069 608 SUPERFAMILY SSF56317 306 576 4.32E-42 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMALA_RS33705 378cefb2c4206d95cf4f248689baf069 608 Gene3D G3DSA:3.60.110.10 294 580 2.2E-41 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMALA_RS33705 378cefb2c4206d95cf4f248689baf069 608 Pfam PF00795 Carbon-nitrogen hydrolase 343 567 7.6E-22 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMALA_RS19675 aaf4f008593d44dd5b74dcfc4c9fb992 381 SMART SM00470 100 190 1.0E-34 T 29-03-2018 IPR003115 ParB/Sulfiredoxin SMALA_RS19675 aaf4f008593d44dd5b74dcfc4c9fb992 381 Pfam PF02195 ParB-like nuclease domain 101 189 2.2E-25 T 29-03-2018 IPR003115 ParB/Sulfiredoxin SMALA_RS19675 aaf4f008593d44dd5b74dcfc4c9fb992 381 Gene3D G3DSA:1.10.10.730 191 238 1.4E-17 T 29-03-2018 SMALA_RS19675 aaf4f008593d44dd5b74dcfc4c9fb992 381 Gene3D G3DSA:3.90.1530.10 88 190 2.0E-37 T 29-03-2018 SMALA_RS19675 aaf4f008593d44dd5b74dcfc4c9fb992 381 SUPERFAMILY SSF109709 182 291 4.97E-33 T 29-03-2018 SMALA_RS19675 aaf4f008593d44dd5b74dcfc4c9fb992 381 SUPERFAMILY SSF110849 93 193 1.1E-28 T 29-03-2018 IPR003115 ParB/Sulfiredoxin SMALA_RS19675 aaf4f008593d44dd5b74dcfc4c9fb992 381 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 98 275 6.2E-60 T 29-03-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 SMALA_RS24055 740adfb1c40c12c8a8124fa8fe0d2599 325 Gene3D G3DSA:3.40.50.2020 9 165 6.6E-61 T 29-03-2018 SMALA_RS24055 740adfb1c40c12c8a8124fa8fe0d2599 325 SUPERFAMILY SSF53271 77 313 1.01E-60 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like SMALA_RS24055 740adfb1c40c12c8a8124fa8fe0d2599 325 Pfam PF14572 Phosphoribosyl synthetase-associated domain 215 321 1.8E-22 T 29-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 SMALA_RS24055 740adfb1c40c12c8a8124fa8fe0d2599 325 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 13 322 4.3E-113 T 29-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 SMALA_RS24055 740adfb1c40c12c8a8124fa8fe0d2599 325 SMART SM01400 12 128 3.5E-70 T 29-03-2018 SMALA_RS24055 740adfb1c40c12c8a8124fa8fe0d2599 325 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 12 128 1.9E-44 T 29-03-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 SMALA_RS24055 740adfb1c40c12c8a8124fa8fe0d2599 325 Hamap MF_00583_B Ribose-phosphate pyrophosphokinase [prs]. 12 322 46.571 T 29-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 SMALA_RS24055 740adfb1c40c12c8a8124fa8fe0d2599 325 Gene3D G3DSA:3.40.50.2020 166 298 1.9E-36 T 29-03-2018 SMALA_RS24055 740adfb1c40c12c8a8124fa8fe0d2599 325 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 136 151 - T 29-03-2018 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 SMALA_RS36955 b68239ff5fd109cf562fb388d979dc43 167 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 2 150 5.6E-24 T 29-03-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 SMALA_RS36955 b68239ff5fd109cf562fb388d979dc43 167 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 2 156 1.2E-25 T 29-03-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 SMALA_RS36955 b68239ff5fd109cf562fb388d979dc43 167 Gene3D G3DSA:3.60.21.10 1 161 1.7E-20 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SMALA_RS36955 b68239ff5fd109cf562fb388d979dc43 167 SUPERFAMILY SSF56300 2 164 6.56E-34 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SMALA_RS02010 04f46a1437a4398a87657f466cda4b28 318 Gene3D G3DSA:1.10.10.10 18 102 1.5E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS02010 04f46a1437a4398a87657f466cda4b28 318 SUPERFAMILY SSF53850 112 317 3.57E-29 T 29-03-2018 SMALA_RS02010 04f46a1437a4398a87657f466cda4b28 318 SUPERFAMILY SSF46785 21 98 6.22E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS02010 04f46a1437a4398a87657f466cda4b28 318 Gene3D G3DSA:3.40.190.10 192 284 2.1E-23 T 29-03-2018 SMALA_RS02010 04f46a1437a4398a87657f466cda4b28 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 60 71 2.0E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS02010 04f46a1437a4398a87657f466cda4b28 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.0E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS02010 04f46a1437a4398a87657f466cda4b28 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 50 60 2.0E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS02010 04f46a1437a4398a87657f466cda4b28 318 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 24 80 2.5E-19 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS02010 04f46a1437a4398a87657f466cda4b28 318 Pfam PF03466 LysR substrate binding domain 113 315 1.2E-27 T 29-03-2018 IPR005119 LysR, substrate-binding SMALA_RS02010 04f46a1437a4398a87657f466cda4b28 318 Gene3D G3DSA:3.40.190.10 112 191 1.0E-8 T 29-03-2018 SMALA_RS28305 2dd129c183bea36a753f820ae2de7093 157 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 39 1.6E-11 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMALA_RS28305 2dd129c183bea36a753f820ae2de7093 157 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 12 28 1.6E-11 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMALA_RS28305 2dd129c183bea36a753f820ae2de7093 157 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 39 58 1.6E-11 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMALA_RS28305 2dd129c183bea36a753f820ae2de7093 157 Pfam PF13404 AsnC-type helix-turn-helix domain 12 52 3.3E-15 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMALA_RS28305 2dd129c183bea36a753f820ae2de7093 157 SUPERFAMILY SSF46785 11 66 3.39E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS28305 2dd129c183bea36a753f820ae2de7093 157 SMART SM00344 12 116 9.2E-36 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 SMALA_RS28305 2dd129c183bea36a753f820ae2de7093 157 Pfam PF01037 Lrp/AsnC ligand binding domain 77 146 1.2E-16 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain SMALA_RS28305 2dd129c183bea36a753f820ae2de7093 157 Gene3D G3DSA:3.30.70.920 64 155 1.1E-18 T 29-03-2018 SMALA_RS28305 2dd129c183bea36a753f820ae2de7093 157 Gene3D G3DSA:1.10.10.10 7 63 4.2E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS28305 2dd129c183bea36a753f820ae2de7093 157 SUPERFAMILY SSF54909 74 153 4.83E-16 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel SMALA_RS28305 2dd129c183bea36a753f820ae2de7093 157 ProSitePatterns PS00519 AsnC-type HTH domain signature. 30 56 - T 29-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site SMALA_RS12805 6c78cd20c62337136feb84d8521ae478 382 Gene3D G3DSA:3.40.50.150 3 262 1.0E-34 T 29-03-2018 SMALA_RS12805 6c78cd20c62337136feb84d8521ae478 382 SUPERFAMILY SSF53335 3 206 2.51E-30 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS12805 6c78cd20c62337136feb84d8521ae478 382 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 38 202 2.5E-32 T 29-03-2018 SMALA_RS30680 57a5aaad8576f2b5a0adedf58b2387cb 248 SUPERFAMILY SSF52540 7 241 4.31E-79 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS30680 57a5aaad8576f2b5a0adedf58b2387cb 248 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS30680 57a5aaad8576f2b5a0adedf58b2387cb 248 Pfam PF00005 ABC transporter 23 171 2.2E-34 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS30680 57a5aaad8576f2b5a0adedf58b2387cb 248 PIRSF PIRSF039085 4 247 5.4E-110 T 29-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 SMALA_RS30680 57a5aaad8576f2b5a0adedf58b2387cb 248 Gene3D G3DSA:3.40.50.300 4 248 2.7E-74 T 29-03-2018 SMALA_RS30680 57a5aaad8576f2b5a0adedf58b2387cb 248 SMART SM00382 32 226 3.7E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS20430 1725ceb7af64af749ecc200695153771 803 Gene3D G3DSA:2.140.10.10 545 663 2.7E-4 T 29-03-2018 SMALA_RS20430 1725ceb7af64af749ecc200695153771 803 Gene3D G3DSA:2.140.10.10 434 544 6.1E-12 T 29-03-2018 SMALA_RS20430 1725ceb7af64af749ecc200695153771 803 Gene3D G3DSA:2.140.10.10 664 795 1.2E-16 T 29-03-2018 SMALA_RS20430 1725ceb7af64af749ecc200695153771 803 SUPERFAMILY SSF50998 439 603 3.66E-12 T 29-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily SMALA_RS20430 1725ceb7af64af749ecc200695153771 803 Gene3D G3DSA:3.30.200.20 9 95 5.3E-14 T 29-03-2018 SMALA_RS20430 1725ceb7af64af749ecc200695153771 803 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 20 42 - T 29-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 SMALA_RS20430 1725ceb7af64af749ecc200695153771 803 Pfam PF13360 PQQ-like domain 661 791 1.6E-12 T 29-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat SMALA_RS20430 1725ceb7af64af749ecc200695153771 803 SMART SM00564 499 535 9.3 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMALA_RS20430 1725ceb7af64af749ecc200695153771 803 SMART SM00564 458 491 200.0 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMALA_RS20430 1725ceb7af64af749ecc200695153771 803 SMART SM00564 685 716 39.0 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMALA_RS20430 1725ceb7af64af749ecc200695153771 803 SMART SM00564 727 758 1.3 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMALA_RS20430 1725ceb7af64af749ecc200695153771 803 SUPERFAMILY SSF50998 547 584 2.82E-14 T 29-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily SMALA_RS20430 1725ceb7af64af749ecc200695153771 803 SUPERFAMILY SSF50998 671 771 2.82E-14 T 29-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily SMALA_RS20430 1725ceb7af64af749ecc200695153771 803 Pfam PF00069 Protein kinase domain 15 260 2.0E-39 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMALA_RS20430 1725ceb7af64af749ecc200695153771 803 SUPERFAMILY SSF56112 11 263 2.83E-59 T 29-03-2018 IPR011009 Protein kinase-like domain SMALA_RS20430 1725ceb7af64af749ecc200695153771 803 SMART SM00220 14 270 9.3E-40 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMALA_RS20430 1725ceb7af64af749ecc200695153771 803 Gene3D G3DSA:1.10.510.10 96 433 1.3E-41 T 29-03-2018 SMALA_RS20430 1725ceb7af64af749ecc200695153771 803 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 132 144 - T 29-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 SUPERFAMILY SSF51735 1222 1409 2.64E-36 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 SUPERFAMILY SSF47336 5622 5709 9.68E-24 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 Gene3D G3DSA:1.10.1200.10 5595 5708 1.7E-22 T 29-03-2018 SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 SUPERFAMILY SSF52151 761 864 6.8E-75 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 SUPERFAMILY SSF52151 572 700 6.8E-75 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 SMART SM00825 Beta-ketoacyl synthase 3884 4310 1.7E-228 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 SMART SM00825 Beta-ketoacyl synthase 1805 2231 1.6E-227 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 SMART SM00825 Beta-ketoacyl synthase 36 462 1.0E-224 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 SUPERFAMILY SSF53901 30 408 1.24E-102 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 SUPERFAMILY SSF53901 1798 2175 2.25E-101 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 Gene3D G3DSA:3.40.366.10 4591 4714 1.2E-27 T 29-03-2018 SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 Pfam PF08990 Erythronolide synthase docking 2 27 6.2E-13 T 29-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2336 2631 1.2E-129 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 576 868 2.4E-125 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 4416 4708 1.5E-127 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3499 3679 1.6E-65 T 29-03-2018 SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1423 1604 5.8E-59 T 29-03-2018 SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5341 5521 2.6E-60 T 29-03-2018 SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 Pfam PF00550 Phosphopantetheine attachment site 5631 5697 2.5E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 Pfam PF00550 Phosphopantetheine attachment site 3787 3853 4.1E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 Pfam PF00550 Phosphopantetheine attachment site 1712 1777 4.1E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 292 409 1.5E-42 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2061 2178 5.7E-44 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 4140 4257 2.6E-44 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 ProSitePatterns PS00012 Phosphopantetheine attachment site. 5656 5671 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 Gene3D G3DSA:3.30.70.250 4548 4590 9.0E-19 T 29-03-2018 SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 Gene3D G3DSA:3.30.70.250 710 751 2.2E-18 T 29-03-2018 SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 Gene3D G3DSA:3.30.70.250 2474 2510 2.4E-18 T 29-03-2018 SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 Gene3D G3DSA:3.90.180.10 3173 3491 1.1E-65 T 29-03-2018 SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 Gene3D G3DSA:1.10.1200.10 3778 3879 2.5E-20 T 29-03-2018 SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 Gene3D G3DSA:1.10.1200.10 1703 1801 8.6E-22 T 29-03-2018 SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 Pfam PF08659 KR domain 3499 3678 4.3E-60 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 Pfam PF08659 KR domain 1423 1603 2.5E-58 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 Pfam PF08659 KR domain 5341 5519 2.8E-57 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 Gene3D G3DSA:3.40.50.720 5083 5336 0.076 T 29-03-2018 SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 4260 4376 8.0E-15 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 412 536 8.5E-14 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2181 2300 6.3E-15 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 SMART SM00823 Phosphopantetheine attachment site 5629 5701 2.0E-36 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 SMART SM00823 Phosphopantetheine attachment site 3785 3857 1.8E-34 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 SMART SM00823 Phosphopantetheine attachment site 1709 1781 1.2E-33 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 Pfam PF14765 Polyketide synthase dehydratase 936 1214 6.3E-58 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 Pfam PF14765 Polyketide synthase dehydratase 2699 2972 5.1E-59 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 Pfam PF14765 Polyketide synthase dehydratase 4775 5050 3.2E-58 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 3203 3259 2.3E-5 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 SUPERFAMILY SSF50129 3198 3316 1.21E-27 T 29-03-2018 IPR011032 GroES-like SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 SUPERFAMILY SSF51735 5340 5555 1.4E-43 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 SUPERFAMILY SSF55048 699 760 2.75E-11 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 SUPERFAMILY SSF55048 2459 2520 7.46E-12 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 Pfam PF00698 Acyl transferase domain 4416 4726 1.6E-56 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 Pfam PF00698 Acyl transferase domain 2335 2650 3.5E-59 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 Pfam PF00698 Acyl transferase domain 575 887 1.3E-59 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 Gene3D G3DSA:3.40.366.10 2511 2638 2.2E-28 T 29-03-2018 SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 Gene3D G3DSA:3.40.366.10 752 875 6.7E-25 T 29-03-2018 SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 SUPERFAMILY SSF51735 1421 1670 3.48E-45 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 SMART SM01294 5630 5697 9.1E-7 T 29-03-2018 SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 SMART SM01294 1710 1777 1.7E-5 T 29-03-2018 SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 SMART SM01294 3786 3853 3.7E-6 T 29-03-2018 SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 4045 4061 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 SUPERFAMILY SSF51735 3493 3738 6.27E-46 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 SUPERFAMILY SSF51735 3282 3418 2.32E-36 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 SUPERFAMILY SSF47336 3780 3896 4.32E-23 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 SUPERFAMILY SSF55048 4539 4600 7.98E-12 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 SUPERFAMILY SSF52151 2333 2454 1.18E-76 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 SUPERFAMILY SSF52151 2513 2621 1.18E-76 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 SMART SM00826 4775 4938 2.3E-86 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 SMART SM00826 2699 2862 2.0E-90 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 SMART SM00826 936 1103 1.3E-89 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 Gene3D G3DSA:3.40.366.10 4412 4547 1.4E-47 T 29-03-2018 SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 Gene3D G3DSA:3.40.366.10 572 709 9.8E-47 T 29-03-2018 SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1736 1751 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3882 4132 6.8E-90 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 284 6.8E-92 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1803 2053 2.7E-87 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 SUPERFAMILY SSF52151 4413 4534 1.96E-75 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 SUPERFAMILY SSF52151 4593 4696 1.96E-75 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 Gene3D G3DSA:3.10.129.10 938 1068 2.0E-5 T 29-03-2018 SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 Gene3D G3DSA:3.10.129.10 2706 2823 4.9E-6 T 29-03-2018 SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 Gene3D G3DSA:3.10.129.10 4777 4901 1.1E-7 T 29-03-2018 SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1966 1982 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 SMART SM00829 3183 3489 3.4E-189 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 Pfam PF13602 Zinc-binding dehydrogenase 3358 3489 1.8E-18 T 29-03-2018 SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 SUPERFAMILY SSF51735 5160 5327 3.35E-28 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 SUPERFAMILY SSF53901 3879 4255 1.63E-102 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 Gene3D G3DSA:3.40.50.720 5337 5594 1.1E-45 T 29-03-2018 SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 Gene3D G3DSA:3.40.50.720 3492 3735 2.6E-50 T 29-03-2018 SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 Gene3D G3DSA:3.40.50.720 1415 1668 2.4E-47 T 29-03-2018 SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 SUPERFAMILY SSF51735 2980 3160 1.97E-33 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 Gene3D G3DSA:3.40.47.10 2068 2229 1.4E-62 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 Gene3D G3DSA:3.40.47.10 299 460 6.0E-61 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 Gene3D G3DSA:3.40.47.10 4147 4308 3.8E-63 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 3311 3332 - T 29-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 197 213 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 Gene3D G3DSA:3.40.366.10 2329 2473 4.1E-51 T 29-03-2018 SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 SUPERFAMILY SSF47336 1704 1818 3.8E-25 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 Gene3D G3DSA:3.40.47.10 1802 2065 3.8E-84 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 Gene3D G3DSA:3.40.47.10 3880 4144 8.4E-86 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13765 f7cee7f97969e8514fb96beb1b75a5e3 5782 Gene3D G3DSA:3.40.47.10 26 296 2.4E-86 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS37680 459ca2b4ea969bc9ec1b3253cc00c316 647 Gene3D G3DSA:1.20.1560.10 13 345 7.6E-61 T 29-03-2018 SMALA_RS37680 459ca2b4ea969bc9ec1b3253cc00c316 647 ProSitePatterns PS01095 Chitinases family 18 active site. 360 368 - T 29-03-2018 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 SMALA_RS37680 459ca2b4ea969bc9ec1b3253cc00c316 647 ProSitePatterns PS00211 ABC transporters family signature. 539 553 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS37680 459ca2b4ea969bc9ec1b3253cc00c316 647 SMART SM00382 427 613 3.5E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS37680 459ca2b4ea969bc9ec1b3253cc00c316 647 Pfam PF00664 ABC transporter transmembrane region 39 310 4.5E-40 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMALA_RS37680 459ca2b4ea969bc9ec1b3253cc00c316 647 SUPERFAMILY SSF52540 414 635 2.17E-84 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS37680 459ca2b4ea969bc9ec1b3253cc00c316 647 Gene3D G3DSA:3.40.50.300 347 641 3.7E-69 T 29-03-2018 SMALA_RS37680 459ca2b4ea969bc9ec1b3253cc00c316 647 Pfam PF00005 ABC transporter 418 567 4.0E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS37680 459ca2b4ea969bc9ec1b3253cc00c316 647 SUPERFAMILY SSF90123 20 345 3.53E-68 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMALA_RS14115 d5e8cf99ae9b678572972d1c10388770 330 Pfam PF14525 AraC-binding-like domain 20 196 3.8E-23 T 29-03-2018 IPR035418 Transcription regulator HTH, AraC- type, ligand binding domain-like SMALA_RS14115 d5e8cf99ae9b678572972d1c10388770 330 Gene3D G3DSA:1.10.10.60 274 328 1.9E-11 T 29-03-2018 SMALA_RS14115 d5e8cf99ae9b678572972d1c10388770 330 Pfam PF12833 Helix-turn-helix domain 243 323 2.2E-22 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS14115 d5e8cf99ae9b678572972d1c10388770 330 SMART SM00342 237 322 4.6E-25 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS14115 d5e8cf99ae9b678572972d1c10388770 330 SUPERFAMILY SSF46689 273 323 2.73E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS14115 d5e8cf99ae9b678572972d1c10388770 330 Gene3D G3DSA:1.10.10.60 216 273 1.2E-8 T 29-03-2018 SMALA_RS11020 86989ce863a69d92dfab3410a666aacc 276 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 264 5.5E-17 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS11020 86989ce863a69d92dfab3410a666aacc 276 Gene3D G3DSA:1.10.3720.10 1 263 2.2E-35 T 29-03-2018 SMALA_RS11020 86989ce863a69d92dfab3410a666aacc 276 SUPERFAMILY SSF161098 3 275 6.17E-54 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS09215 17df2fd008c6ceaeac52fb75cf741806 344 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 194 207 - T 29-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 SMALA_RS09215 17df2fd008c6ceaeac52fb75cf741806 344 Gene3D G3DSA:3.40.640.10 42 224 2.1E-26 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS09215 17df2fd008c6ceaeac52fb75cf741806 344 Gene3D G3DSA:3.90.1150.10 225 338 3.1E-23 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS09215 17df2fd008c6ceaeac52fb75cf741806 344 SUPERFAMILY SSF53383 14 338 5.54E-62 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS09215 17df2fd008c6ceaeac52fb75cf741806 344 Pfam PF00155 Aminotransferase class I and II 18 332 6.8E-34 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMALA_RS28110 8acc7c516f3686420fe9b78277633290 846 PIRSF PIRSF006288 2 844 3.1E-193 T 29-03-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 SMALA_RS28110 8acc7c516f3686420fe9b78277633290 846 Gene3D G3DSA:3.30.70.260 765 840 2.7E-10 T 29-03-2018 SMALA_RS28110 8acc7c516f3686420fe9b78277633290 846 Gene3D G3DSA:3.30.70.260 637 748 3.1E-11 T 29-03-2018 SMALA_RS28110 8acc7c516f3686420fe9b78277633290 846 SUPERFAMILY SSF55021 770 820 1.46E-7 T 29-03-2018 SMALA_RS28110 8acc7c516f3686420fe9b78277633290 846 SUPERFAMILY SSF81301 32 156 8.33E-15 T 29-03-2018 SMALA_RS28110 8acc7c516f3686420fe9b78277633290 846 Pfam PF01966 HD domain 441 558 1.8E-13 T 29-03-2018 IPR006674 HD domain SMALA_RS28110 8acc7c516f3686420fe9b78277633290 846 Pfam PF01909 Nucleotidyltransferase domain 58 120 1.1E-5 T 29-03-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 SMALA_RS28110 8acc7c516f3686420fe9b78277633290 846 Gene3D G3DSA:3.30.460.10 21 161 3.4E-13 T 29-03-2018 SMALA_RS28110 8acc7c516f3686420fe9b78277633290 846 SUPERFAMILY SSF109604 407 556 1.94E-16 T 29-03-2018 SMALA_RS28110 8acc7c516f3686420fe9b78277633290 846 Hamap MF_00277 Bifunctional uridylyltransferase/uridylyl-removing enzyme [glnD]. 1 846 93.805 T 29-03-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 SMALA_RS28110 8acc7c516f3686420fe9b78277633290 846 TIGRFAM TIGR01693 UTase_glnD: protein-P-II uridylyltransferase 17 839 1.8E-235 T 29-03-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 SMALA_RS28110 8acc7c516f3686420fe9b78277633290 846 Gene3D G3DSA:1.10.3090.10 341 600 6.1E-39 T 29-03-2018 SMALA_RS28110 8acc7c516f3686420fe9b78277633290 846 Gene3D G3DSA:1.20.120.330 202 283 7.0E-6 T 29-03-2018 SMALA_RS28110 8acc7c516f3686420fe9b78277633290 846 Pfam PF08335 GlnD PII-uridylyltransferase 208 280 5.9E-5 T 29-03-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 SMALA_RS28110 8acc7c516f3686420fe9b78277633290 846 Pfam PF08335 GlnD PII-uridylyltransferase 170 207 1.1E-4 T 29-03-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 SMALA_RS28110 8acc7c516f3686420fe9b78277633290 846 SMART SM00471 436 568 1.1E-8 T 29-03-2018 IPR003607 HD/PDEase domain SMALA_RS23460 3152472b35c6b09366cec953a7a75ca1 579 SUPERFAMILY SSF51182 230 467 1.18E-49 T 29-03-2018 IPR011051 RmlC-like cupin domain SMALA_RS23460 3152472b35c6b09366cec953a7a75ca1 579 SUPERFAMILY SSF51182 494 567 1.18E-49 T 29-03-2018 IPR011051 RmlC-like cupin domain SMALA_RS23460 3152472b35c6b09366cec953a7a75ca1 579 Gene3D G3DSA:2.60.120.10 229 469 2.6E-30 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SMALA_RS23460 3152472b35c6b09366cec953a7a75ca1 579 Gene3D G3DSA:2.60.120.10 492 578 3.1E-13 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SMALA_RS23460 3152472b35c6b09366cec953a7a75ca1 579 PIRSF PIRSF026713 11 579 6.2E-207 T 29-03-2018 IPR016847 Mannose-6-phosphate isomerase, Firmicutes, long form, predicted SMALA_RS10300 7215dfd63cede3fd7090cb199c98a579 694 Gene3D G3DSA:3.40.1710.10 47 188 3.3E-24 T 29-03-2018 SMALA_RS10300 7215dfd63cede3fd7090cb199c98a579 694 Pfam PF12698 ABC-2 family transporter protein 491 674 9.2E-15 T 29-03-2018 SMALA_RS10300 7215dfd63cede3fd7090cb199c98a579 694 Pfam PF12698 ABC-2 family transporter protein 26 150 2.6E-8 T 29-03-2018 SMALA_RS10300 7215dfd63cede3fd7090cb199c98a579 694 Gene3D G3DSA:1.20.120.570 328 469 4.6E-9 T 29-03-2018 SMALA_RS10300 7215dfd63cede3fd7090cb199c98a579 694 Gene3D G3DSA:1.20.1480.30 189 297 0.05 T 29-03-2018 SMALA_RS10300 7215dfd63cede3fd7090cb199c98a579 694 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 394 420 1.4E-4 T 29-03-2018 IPR023908 xxxLxxG heptad repeat SMALA_RS10300 7215dfd63cede3fd7090cb199c98a579 694 TIGRFAM TIGR03062 pip_yhgE_Cterm: YhgE/Pip C-terminal domain 476 681 3.7E-71 T 29-03-2018 IPR017501 Phage infection protein, YhgE, C-terminal SMALA_RS10300 7215dfd63cede3fd7090cb199c98a579 694 TIGRFAM TIGR03061 pip_yhgE_Nterm: YhgE/Pip N-terminal domain 10 172 3.2E-57 T 29-03-2018 IPR017500 Phage infection protein, YhgE, N-terminal SMALA_RS11435 fe78dae75d6877f8c0f0b0bb54023014 194 Gene3D G3DSA:3.40.50.2300 1 119 2.5E-10 T 29-03-2018 SMALA_RS11435 fe78dae75d6877f8c0f0b0bb54023014 194 SUPERFAMILY SSF46894 123 193 3.4E-17 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS11435 fe78dae75d6877f8c0f0b0bb54023014 194 SMART SM00421 131 188 5.8E-20 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS11435 fe78dae75d6877f8c0f0b0bb54023014 194 SUPERFAMILY SSF52172 3 120 8.0E-7 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS11435 fe78dae75d6877f8c0f0b0bb54023014 194 Pfam PF00196 Bacterial regulatory proteins, luxR family 133 187 1.1E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS11435 fe78dae75d6877f8c0f0b0bb54023014 194 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 148 164 1.6E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS11435 fe78dae75d6877f8c0f0b0bb54023014 194 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 134 148 1.6E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS11435 fe78dae75d6877f8c0f0b0bb54023014 194 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 176 1.6E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS11435 fe78dae75d6877f8c0f0b0bb54023014 194 Gene3D G3DSA:1.10.10.10 120 194 1.2E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS41615 ac84f9211875431c3fae55ec78d1fa6f 507 SUPERFAMILY SSF52540 4 220 3.32E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS41615 ac84f9211875431c3fae55ec78d1fa6f 507 ProSitePatterns PS00211 ABC transporters family signature. 395 409 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS41615 ac84f9211875431c3fae55ec78d1fa6f 507 Pfam PF00005 ABC transporter 21 168 4.7E-22 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS41615 ac84f9211875431c3fae55ec78d1fa6f 507 Pfam PF00005 ABC transporter 267 423 1.1E-13 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS41615 ac84f9211875431c3fae55ec78d1fa6f 507 SMART SM00382 275 471 0.77 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS41615 ac84f9211875431c3fae55ec78d1fa6f 507 SMART SM00382 30 216 2.8E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS41615 ac84f9211875431c3fae55ec78d1fa6f 507 Gene3D G3DSA:3.40.50.300 262 495 2.4E-32 T 29-03-2018 SMALA_RS41615 ac84f9211875431c3fae55ec78d1fa6f 507 Gene3D G3DSA:3.40.50.300 2 225 2.1E-50 T 29-03-2018 SMALA_RS41615 ac84f9211875431c3fae55ec78d1fa6f 507 SUPERFAMILY SSF52540 266 481 2.15E-37 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS37855 cf19e6bf4dd83c9debdad63c5e57571b 2308 SUPERFAMILY SSF50129 1573 1693 2.52E-25 T 29-03-2018 IPR011032 GroES-like SMALA_RS37855 cf19e6bf4dd83c9debdad63c5e57571b 2308 SMART SM00829 1560 1866 5.9E-177 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS37855 cf19e6bf4dd83c9debdad63c5e57571b 2308 Pfam PF00550 Phosphopantetheine attachment site 2161 2226 8.1E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS37855 cf19e6bf4dd83c9debdad63c5e57571b 2308 Pfam PF00550 Phosphopantetheine attachment site 49 114 4.4E-9 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS37855 cf19e6bf4dd83c9debdad63c5e57571b 2308 Gene3D G3DSA:1.10.1200.10 28 118 3.7E-14 T 29-03-2018 SMALA_RS37855 cf19e6bf4dd83c9debdad63c5e57571b 2308 Gene3D G3DSA:3.40.50.720 1697 1796 8.0E-15 T 29-03-2018 SMALA_RS37855 cf19e6bf4dd83c9debdad63c5e57571b 2308 SMART SM00825 Beta-ketoacyl synthase 139 565 2.2E-215 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS37855 cf19e6bf4dd83c9debdad63c5e57571b 2308 SMART SM01294 2159 2226 9.2E-5 T 29-03-2018 SMALA_RS37855 cf19e6bf4dd83c9debdad63c5e57571b 2308 SMART SM01294 47 114 1.2E-4 T 29-03-2018 SMALA_RS37855 cf19e6bf4dd83c9debdad63c5e57571b 2308 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 395 512 7.7E-44 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS37855 cf19e6bf4dd83c9debdad63c5e57571b 2308 SUPERFAMILY SSF47336 41 152 3.14E-20 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS37855 cf19e6bf4dd83c9debdad63c5e57571b 2308 Gene3D G3DSA:3.40.50.720 1874 2142 3.2E-52 T 29-03-2018 SMALA_RS37855 cf19e6bf4dd83c9debdad63c5e57571b 2308 Gene3D G3DSA:3.90.180.10 1531 1696 1.0E-38 T 29-03-2018 SMALA_RS37855 cf19e6bf4dd83c9debdad63c5e57571b 2308 Gene3D G3DSA:3.40.47.10 131 399 2.1E-82 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS37855 cf19e6bf4dd83c9debdad63c5e57571b 2308 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 137 387 6.8E-90 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS37855 cf19e6bf4dd83c9debdad63c5e57571b 2308 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 1580 1638 9.0E-7 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS37855 cf19e6bf4dd83c9debdad63c5e57571b 2308 SUPERFAMILY SSF51735 1875 2071 1.57E-49 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS37855 cf19e6bf4dd83c9debdad63c5e57571b 2308 SUPERFAMILY SSF52151 876 972 4.19E-75 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS37855 cf19e6bf4dd83c9debdad63c5e57571b 2308 SUPERFAMILY SSF52151 669 812 4.19E-75 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS37855 cf19e6bf4dd83c9debdad63c5e57571b 2308 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 515 637 1.3E-17 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37855 cf19e6bf4dd83c9debdad63c5e57571b 2308 Gene3D G3DSA:3.30.70.250 825 866 2.0E-21 T 29-03-2018 SMALA_RS37855 cf19e6bf4dd83c9debdad63c5e57571b 2308 Pfam PF08659 KR domain 1876 2054 1.3E-62 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37855 cf19e6bf4dd83c9debdad63c5e57571b 2308 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 673 984 3.8E-123 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS37855 cf19e6bf4dd83c9debdad63c5e57571b 2308 Pfam PF14765 Polyketide synthase dehydratase 1052 1326 2.5E-55 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37855 cf19e6bf4dd83c9debdad63c5e57571b 2308 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1876 2056 2.7E-66 T 29-03-2018 SMALA_RS37855 cf19e6bf4dd83c9debdad63c5e57571b 2308 Pfam PF00107 Zinc-binding dehydrogenase 1699 1790 1.9E-15 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMALA_RS37855 cf19e6bf4dd83c9debdad63c5e57571b 2308 Pfam PF00698 Acyl transferase domain 672 1001 5.4E-62 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS37855 cf19e6bf4dd83c9debdad63c5e57571b 2308 SUPERFAMILY SSF51735 1659 1816 9.51E-37 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS37855 cf19e6bf4dd83c9debdad63c5e57571b 2308 Gene3D G3DSA:1.10.1200.10 2153 2294 1.3E-19 T 29-03-2018 SMALA_RS37855 cf19e6bf4dd83c9debdad63c5e57571b 2308 Gene3D G3DSA:3.40.366.10 867 992 6.7E-29 T 29-03-2018 SMALA_RS37855 cf19e6bf4dd83c9debdad63c5e57571b 2308 Gene3D G3DSA:3.40.47.10 402 563 4.8E-62 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS37855 cf19e6bf4dd83c9debdad63c5e57571b 2308 SMART SM00826 1052 1216 7.5E-75 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37855 cf19e6bf4dd83c9debdad63c5e57571b 2308 SMART SM00823 Phosphopantetheine attachment site 46 118 1.1E-19 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37855 cf19e6bf4dd83c9debdad63c5e57571b 2308 SMART SM00823 Phosphopantetheine attachment site 2158 2230 8.7E-31 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37855 cf19e6bf4dd83c9debdad63c5e57571b 2308 SUPERFAMILY SSF47336 2152 2236 3.66E-21 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS37855 cf19e6bf4dd83c9debdad63c5e57571b 2308 Gene3D G3DSA:3.40.366.10 669 824 7.6E-50 T 29-03-2018 SMALA_RS37855 cf19e6bf4dd83c9debdad63c5e57571b 2308 Gene3D G3DSA:3.90.180.10 1797 1870 0.043 T 29-03-2018 SMALA_RS37855 cf19e6bf4dd83c9debdad63c5e57571b 2308 SUPERFAMILY SSF51735 1338 1536 6.68E-34 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS37855 cf19e6bf4dd83c9debdad63c5e57571b 2308 SUPERFAMILY SSF53901 134 511 8.86E-103 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS37855 cf19e6bf4dd83c9debdad63c5e57571b 2308 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 300 316 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS37855 cf19e6bf4dd83c9debdad63c5e57571b 2308 SUPERFAMILY SSF55048 811 875 2.09E-13 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS16320 6de19155332b07ef43201b989f80bf3f 264 Gene3D G3DSA:3.90.226.10 1 214 9.0E-68 T 29-03-2018 SMALA_RS16320 6de19155332b07ef43201b989f80bf3f 264 SUPERFAMILY SSF52096 8 263 1.57E-80 T 29-03-2018 IPR029045 ClpP/crotonase-like domain SMALA_RS16320 6de19155332b07ef43201b989f80bf3f 264 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 105 125 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 SMALA_RS16320 6de19155332b07ef43201b989f80bf3f 264 Pfam PF00378 Enoyl-CoA hydratase/isomerase 18 262 7.1E-58 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 SMALA_RS16320 6de19155332b07ef43201b989f80bf3f 264 Gene3D G3DSA:1.10.12.10 215 264 1.4E-16 T 29-03-2018 IPR014748 Crontonase, C-terminal SMALA_RS37125 dac45feed81ecd4568395ac7470cb737 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 152 166 8.4E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS37125 dac45feed81ecd4568395ac7470cb737 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 182 8.4E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS37125 dac45feed81ecd4568395ac7470cb737 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 182 194 8.4E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS37125 dac45feed81ecd4568395ac7470cb737 212 SMART SM00421 149 206 1.8E-20 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS37125 dac45feed81ecd4568395ac7470cb737 212 Gene3D G3DSA:3.40.50.2300 8 123 7.7E-8 T 29-03-2018 SMALA_RS37125 dac45feed81ecd4568395ac7470cb737 212 ProSitePatterns PS00622 LuxR-type HTH domain signature. 166 193 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS37125 dac45feed81ecd4568395ac7470cb737 212 Pfam PF00196 Bacterial regulatory proteins, luxR family 152 206 1.3E-15 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS37125 dac45feed81ecd4568395ac7470cb737 212 Gene3D G3DSA:1.10.10.10 124 212 1.0E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS37125 dac45feed81ecd4568395ac7470cb737 212 SUPERFAMILY SSF46894 147 212 7.14E-18 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS11055 bff1ddef7493bff8f35ee41458dbee25 179 SUPERFAMILY SSF51569 26 177 8.2E-26 T 29-03-2018 SMALA_RS11055 bff1ddef7493bff8f35ee41458dbee25 179 Gene3D G3DSA:3.20.20.70 8 179 1.1E-34 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS11055 bff1ddef7493bff8f35ee41458dbee25 179 SMART SM01004 5 177 2.5E-5 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 SMALA_RS11055 bff1ddef7493bff8f35ee41458dbee25 179 Pfam PF00490 Delta-aminolevulinic acid dehydratase 26 175 6.7E-28 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 SMALA_RS15030 ad6571a8e7c88932129ce474cd87e981 434 Gene3D G3DSA:3.90.550.10 37 226 1.7E-14 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS15030 ad6571a8e7c88932129ce474cd87e981 434 Pfam PF00535 Glycosyl transferase family 2 62 153 1.9E-10 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 SMALA_RS15030 ad6571a8e7c88932129ce474cd87e981 434 SUPERFAMILY SSF53448 59 188 1.78E-15 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS16030 68d6dcdfaaca643fab73033a1aa86b21 395 Gene3D G3DSA:2.30.40.10 338 395 1.8E-10 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS16030 68d6dcdfaaca643fab73033a1aa86b21 395 TIGRFAM TIGR01224 hutI: imidazolonepropionase 35 393 3.9E-109 T 29-03-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 SMALA_RS16030 68d6dcdfaaca643fab73033a1aa86b21 395 Hamap MF_00372 Imidazolonepropionase [hutI]. 10 395 42.469 T 29-03-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 SMALA_RS16030 68d6dcdfaaca643fab73033a1aa86b21 395 SUPERFAMILY SSF51556 71 353 1.0E-66 T 29-03-2018 IPR032466 Metal-dependent hydrolase SMALA_RS16030 68d6dcdfaaca643fab73033a1aa86b21 395 SUPERFAMILY SSF51338 355 394 2.55E-14 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS16030 68d6dcdfaaca643fab73033a1aa86b21 395 SUPERFAMILY SSF51338 32 72 2.55E-14 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS16030 68d6dcdfaaca643fab73033a1aa86b21 395 Gene3D G3DSA:3.20.20.140 88 337 3.7E-39 T 29-03-2018 SMALA_RS16030 68d6dcdfaaca643fab73033a1aa86b21 395 Pfam PF01979 Amidohydrolase family 255 370 6.7E-16 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 SMALA_RS16030 68d6dcdfaaca643fab73033a1aa86b21 395 Gene3D G3DSA:2.30.40.10 11 87 2.3E-20 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS36705 4151aae1050e700b7226d541b62bd79d 4083 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 2019 2035 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS36705 4151aae1050e700b7226d541b62bd79d 4083 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 292 409 5.0E-44 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS36705 4151aae1050e700b7226d541b62bd79d 4083 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2114 2231 1.0E-43 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS36705 4151aae1050e700b7226d541b62bd79d 4083 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2399 2702 5.5E-115 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS36705 4151aae1050e700b7226d541b62bd79d 4083 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 597 905 1.5E-129 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS36705 4151aae1050e700b7226d541b62bd79d 4083 Pfam PF00550 Phosphopantetheine attachment site 1764 1830 9.6E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS36705 4151aae1050e700b7226d541b62bd79d 4083 Pfam PF00550 Phosphopantetheine attachment site 3929 3994 5.8E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS36705 4151aae1050e700b7226d541b62bd79d 4083 SMART SM01294 1763 1830 5.9E-6 T 29-03-2018 SMALA_RS36705 4151aae1050e700b7226d541b62bd79d 4083 SMART SM01294 3927 3994 2.8E-5 T 29-03-2018 SMALA_RS36705 4151aae1050e700b7226d541b62bd79d 4083 SUPERFAMILY SSF47336 1757 1870 1.44E-24 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS36705 4151aae1050e700b7226d541b62bd79d 4083 Gene3D G3DSA:1.10.1200.10 3919 4028 5.2E-19 T 29-03-2018 SMALA_RS36705 4151aae1050e700b7226d541b62bd79d 4083 Gene3D G3DSA:1.10.1200.10 1757 1853 6.5E-20 T 29-03-2018 SMALA_RS36705 4151aae1050e700b7226d541b62bd79d 4083 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1789 1804 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS36705 4151aae1050e700b7226d541b62bd79d 4083 Gene3D G3DSA:3.90.180.10 3553 3630 0.0023 T 29-03-2018 SMALA_RS36705 4151aae1050e700b7226d541b62bd79d 4083 Pfam PF00698 Acyl transferase domain 596 887 2.7E-54 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS36705 4151aae1050e700b7226d541b62bd79d 4083 Pfam PF00698 Acyl transferase domain 2398 2721 5.5E-84 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS36705 4151aae1050e700b7226d541b62bd79d 4083 Gene3D G3DSA:3.40.47.10 299 460 4.2E-61 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS36705 4151aae1050e700b7226d541b62bd79d 4083 Gene3D G3DSA:3.40.47.10 2121 2282 1.5E-62 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS36705 4151aae1050e700b7226d541b62bd79d 4083 SUPERFAMILY SSF51735 3419 3557 1.28E-40 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS36705 4151aae1050e700b7226d541b62bd79d 4083 SMART SM00826 2771 2938 1.2E-73 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS36705 4151aae1050e700b7226d541b62bd79d 4083 SMART SM00826 971 1141 2.7E-73 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS36705 4151aae1050e700b7226d541b62bd79d 4083 Gene3D G3DSA:3.40.47.10 1854 2118 1.7E-86 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS36705 4151aae1050e700b7226d541b62bd79d 4083 Gene3D G3DSA:3.40.47.10 28 296 5.1E-84 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS36705 4151aae1050e700b7226d541b62bd79d 4083 Pfam PF14765 Polyketide synthase dehydratase 971 1256 1.3E-51 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS36705 4151aae1050e700b7226d541b62bd79d 4083 Pfam PF14765 Polyketide synthase dehydratase 2771 3077 1.2E-46 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS36705 4151aae1050e700b7226d541b62bd79d 4083 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3953 3968 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS36705 4151aae1050e700b7226d541b62bd79d 4083 SMART SM00823 Phosphopantetheine attachment site 1762 1834 1.0E-29 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS36705 4151aae1050e700b7226d541b62bd79d 4083 SMART SM00823 Phosphopantetheine attachment site 3926 3998 3.8E-30 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS36705 4151aae1050e700b7226d541b62bd79d 4083 Gene3D G3DSA:3.30.70.250 735 777 2.7E-21 T 29-03-2018 SMALA_RS36705 4151aae1050e700b7226d541b62bd79d 4083 SUPERFAMILY SSF53901 33 400 1.52E-103 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS36705 4151aae1050e700b7226d541b62bd79d 4083 SMART SM00825 Beta-ketoacyl synthase 38 462 9.9E-221 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS36705 4151aae1050e700b7226d541b62bd79d 4083 SMART SM00825 Beta-ketoacyl synthase 1857 2284 8.2E-223 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS36705 4151aae1050e700b7226d541b62bd79d 4083 SUPERFAMILY SSF50129 3335 3446 1.57E-28 T 29-03-2018 IPR011032 GroES-like SMALA_RS36705 4151aae1050e700b7226d541b62bd79d 4083 Gene3D G3DSA:3.40.50.720 3450 3552 1.3E-19 T 29-03-2018 SMALA_RS36705 4151aae1050e700b7226d541b62bd79d 4083 SUPERFAMILY SSF52151 2591 2693 1.75E-64 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS36705 4151aae1050e700b7226d541b62bd79d 4083 SUPERFAMILY SSF52151 2397 2524 1.75E-64 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS36705 4151aae1050e700b7226d541b62bd79d 4083 Pfam PF08990 Erythronolide synthase docking 4 29 6.5E-12 T 29-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 SMALA_RS36705 4151aae1050e700b7226d541b62bd79d 4083 SUPERFAMILY SSF101173 3 36 2.88E-5 T 29-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 SMALA_RS36705 4151aae1050e700b7226d541b62bd79d 4083 SUPERFAMILY SSF47336 3919 4006 1.96E-22 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS36705 4151aae1050e700b7226d541b62bd79d 4083 SUPERFAMILY SSF53901 1851 2222 3.55E-101 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS36705 4151aae1050e700b7226d541b62bd79d 4083 SUPERFAMILY SSF51735 3635 3832 3.74E-41 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS36705 4151aae1050e700b7226d541b62bd79d 4083 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3637 3817 9.1E-53 T 29-03-2018 SMALA_RS36705 4151aae1050e700b7226d541b62bd79d 4083 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1479 1660 1.0E-52 T 29-03-2018 SMALA_RS36705 4151aae1050e700b7226d541b62bd79d 4083 Gene3D G3DSA:3.40.366.10 590 734 1.4E-43 T 29-03-2018 SMALA_RS36705 4151aae1050e700b7226d541b62bd79d 4083 Gene3D G3DSA:3.40.366.10 2393 2531 7.5E-42 T 29-03-2018 SMALA_RS36705 4151aae1050e700b7226d541b62bd79d 4083 SUPERFAMILY SSF51735 1267 1465 6.3E-35 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS36705 4151aae1050e700b7226d541b62bd79d 4083 Gene3D G3DSA:3.40.366.10 778 893 7.9E-35 T 29-03-2018 SMALA_RS36705 4151aae1050e700b7226d541b62bd79d 4083 Gene3D G3DSA:3.10.129.10 973 1093 2.9E-5 T 29-03-2018 SMALA_RS36705 4151aae1050e700b7226d541b62bd79d 4083 Gene3D G3DSA:3.10.129.10 2773 2891 7.5E-6 T 29-03-2018 SMALA_RS36705 4151aae1050e700b7226d541b62bd79d 4083 Gene3D G3DSA:3.40.50.720 1472 1732 1.3E-45 T 29-03-2018 SMALA_RS36705 4151aae1050e700b7226d541b62bd79d 4083 Gene3D G3DSA:3.40.50.720 3631 3883 1.7E-44 T 29-03-2018 SMALA_RS36705 4151aae1050e700b7226d541b62bd79d 4083 SUPERFAMILY SSF52151 594 725 1.26E-71 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS36705 4151aae1050e700b7226d541b62bd79d 4083 SUPERFAMILY SSF52151 789 883 1.26E-71 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS36705 4151aae1050e700b7226d541b62bd79d 4083 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 36 284 4.7E-88 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS36705 4151aae1050e700b7226d541b62bd79d 4083 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1855 2106 1.3E-88 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS36705 4151aae1050e700b7226d541b62bd79d 4083 Gene3D G3DSA:3.90.180.10 3314 3449 9.7E-36 T 29-03-2018 SMALA_RS36705 4151aae1050e700b7226d541b62bd79d 4083 Pfam PF00107 Zinc-binding dehydrogenase 3459 3550 9.6E-19 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMALA_RS36705 4151aae1050e700b7226d541b62bd79d 4083 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 3339 3395 2.1E-5 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS36705 4151aae1050e700b7226d541b62bd79d 4083 SUPERFAMILY SSF51735 1476 1715 6.67E-45 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS36705 4151aae1050e700b7226d541b62bd79d 4083 Gene3D G3DSA:3.40.366.10 2583 2709 1.4E-23 T 29-03-2018 SMALA_RS36705 4151aae1050e700b7226d541b62bd79d 4083 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 412 559 5.5E-14 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS36705 4151aae1050e700b7226d541b62bd79d 4083 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2234 2359 3.2E-15 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS36705 4151aae1050e700b7226d541b62bd79d 4083 Pfam PF08659 KR domain 1479 1658 1.8E-56 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS36705 4151aae1050e700b7226d541b62bd79d 4083 Pfam PF08659 KR domain 3637 3816 8.5E-56 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS36705 4151aae1050e700b7226d541b62bd79d 4083 Gene3D G3DSA:3.30.70.250 2532 2582 4.3E-14 T 29-03-2018 SMALA_RS36705 4151aae1050e700b7226d541b62bd79d 4083 SUPERFAMILY SSF55048 2522 2590 1.44E-10 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS36705 4151aae1050e700b7226d541b62bd79d 4083 SMART SM00829 3320 3627 3.0E-183 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS36705 4151aae1050e700b7226d541b62bd79d 4083 SUPERFAMILY SSF51735 3086 3296 2.52E-24 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS36705 4151aae1050e700b7226d541b62bd79d 4083 SUPERFAMILY SSF55048 724 788 5.23E-14 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS36705 4151aae1050e700b7226d541b62bd79d 4083 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 197 213 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS11730 36fa9fc925733c787ae383523e0c56ec 201 Gene3D G3DSA:3.90.226.10 4 197 1.1E-39 T 29-03-2018 SMALA_RS11730 36fa9fc925733c787ae383523e0c56ec 201 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 5 196 36.603 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMALA_RS11730 36fa9fc925733c787ae383523e0c56ec 201 PRINTS PR00127 Clp protease catalytic subunit P signature 92 109 2.3E-40 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMALA_RS11730 36fa9fc925733c787ae383523e0c56ec 201 PRINTS PR00127 Clp protease catalytic subunit P signature 61 81 2.3E-40 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMALA_RS11730 36fa9fc925733c787ae383523e0c56ec 201 PRINTS PR00127 Clp protease catalytic subunit P signature 171 190 2.3E-40 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMALA_RS11730 36fa9fc925733c787ae383523e0c56ec 201 PRINTS PR00127 Clp protease catalytic subunit P signature 21 36 2.3E-40 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMALA_RS11730 36fa9fc925733c787ae383523e0c56ec 201 PRINTS PR00127 Clp protease catalytic subunit P signature 113 132 2.3E-40 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMALA_RS11730 36fa9fc925733c787ae383523e0c56ec 201 Pfam PF00574 Clp protease 15 195 2.4E-69 T 29-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA SMALA_RS11730 36fa9fc925733c787ae383523e0c56ec 201 SUPERFAMILY SSF52096 14 196 6.08E-58 T 29-03-2018 IPR029045 ClpP/crotonase-like domain SMALA_RS30775 53ffc0296dbdd3edd2c2ac0da445d5bb 345 Pfam PF16864 Dimerisation domain 16 86 4.5E-8 T 29-03-2018 IPR031725 Acetylserotonin O-methyltransferase, dimerisation domain SMALA_RS30775 53ffc0296dbdd3edd2c2ac0da445d5bb 345 SUPERFAMILY SSF53335 107 326 2.66E-34 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS30775 53ffc0296dbdd3edd2c2ac0da445d5bb 345 PIRSF PIRSF005739 2 329 3.6E-14 T 29-03-2018 IPR016461 O-methyltransferase COMT-type GO:0008168 SMALA_RS30775 53ffc0296dbdd3edd2c2ac0da445d5bb 345 SUPERFAMILY SSF46785 12 91 2.99E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS30775 53ffc0296dbdd3edd2c2ac0da445d5bb 345 Gene3D G3DSA:1.10.10.10 10 90 1.3E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS30775 53ffc0296dbdd3edd2c2ac0da445d5bb 345 Gene3D G3DSA:3.40.50.150 97 345 2.9E-34 T 29-03-2018 SMALA_RS30775 53ffc0296dbdd3edd2c2ac0da445d5bb 345 Pfam PF00891 O-methyltransferase 137 324 2.1E-26 T 29-03-2018 IPR001077 O-methyltransferase, family 2 GO:0008171 SMALA_RS02935 c662db0c60c50362181893db7d117839 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 4.1E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS02935 c662db0c60c50362181893db7d117839 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 4.1E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS02935 c662db0c60c50362181893db7d117839 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 4.1E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS02935 c662db0c60c50362181893db7d117839 309 SUPERFAMILY SSF46785 1 110 2.11E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS02935 c662db0c60c50362181893db7d117839 309 Gene3D G3DSA:3.40.190.10 92 177 1.1E-21 T 29-03-2018 SMALA_RS02935 c662db0c60c50362181893db7d117839 309 Gene3D G3DSA:3.40.190.10 178 266 3.6E-19 T 29-03-2018 SMALA_RS02935 c662db0c60c50362181893db7d117839 309 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 3.4E-21 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS02935 c662db0c60c50362181893db7d117839 309 SUPERFAMILY SSF53850 88 297 1.22E-35 T 29-03-2018 SMALA_RS02935 c662db0c60c50362181893db7d117839 309 Gene3D G3DSA:1.10.10.10 1 91 3.5E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS02935 c662db0c60c50362181893db7d117839 309 Pfam PF03466 LysR substrate binding domain 88 294 5.1E-34 T 29-03-2018 IPR005119 LysR, substrate-binding SMALA_RS39310 aa210ca06f98bd18164cccb4bee71ec7 305 SUPERFAMILY SSF56112 1 291 1.5E-44 T 29-03-2018 IPR011009 Protein kinase-like domain SMALA_RS39310 aa210ca06f98bd18164cccb4bee71ec7 305 Pfam PF01636 Phosphotransferase enzyme family 34 267 3.4E-32 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase SMALA_RS39310 aa210ca06f98bd18164cccb4bee71ec7 305 Gene3D G3DSA:3.90.1200.10 102 272 8.3E-23 T 29-03-2018 SMALA_RS29865 dfd0bab09a9b70c0309e4c6c14263cb4 270 SUPERFAMILY SSF55781 73 255 2.68E-44 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS29865 dfd0bab09a9b70c0309e4c6c14263cb4 270 Gene3D G3DSA:3.30.450.40 91 268 1.5E-45 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS29865 dfd0bab09a9b70c0309e4c6c14263cb4 270 SUPERFAMILY SSF46785 19 85 5.0E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS29865 dfd0bab09a9b70c0309e4c6c14263cb4 270 Gene3D G3DSA:1.10.10.10 4 76 9.5E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS29865 dfd0bab09a9b70c0309e4c6c14263cb4 270 Pfam PF09339 IclR helix-turn-helix domain 21 68 2.7E-14 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMALA_RS29865 dfd0bab09a9b70c0309e4c6c14263cb4 270 Pfam PF01614 Bacterial transcriptional regulator 133 253 1.1E-23 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal SMALA_RS29865 dfd0bab09a9b70c0309e4c6c14263cb4 270 SMART SM00346 15 105 9.5E-22 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMALA_RS29035 b94732ec4a1a5df4cbd55b6986240bd2 733 SUPERFAMILY SSF52540 2 217 4.91E-40 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS29035 b94732ec4a1a5df4cbd55b6986240bd2 733 Pfam PF00005 ABC transporter 20 156 4.0E-19 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS29035 b94732ec4a1a5df4cbd55b6986240bd2 733 SMART SM00382 28 205 4.4E-4 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS29035 b94732ec4a1a5df4cbd55b6986240bd2 733 Gene3D G3DSA:3.40.50.300 1 353 2.1E-43 T 29-03-2018 SMALA_RS17650 8839fa6e4275e8fb28e7e3314e5705ad 266 Pfam PF00483 Nucleotidyl transferase 21 247 3.0E-23 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 SMALA_RS17650 8839fa6e4275e8fb28e7e3314e5705ad 266 Gene3D G3DSA:3.90.550.10 11 257 4.3E-48 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS17650 8839fa6e4275e8fb28e7e3314e5705ad 266 SUPERFAMILY SSF53448 19 254 4.38E-53 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 Gene3D G3DSA:3.40.50.720 3911 4171 3.1E-55 T 29-03-2018 SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 Gene3D G3DSA:3.40.50.720 2367 2630 2.1E-47 T 29-03-2018 SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 Gene3D G3DSA:3.40.50.720 6027 6282 1.3E-41 T 29-03-2018 SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 3289 3584 2.0E-111 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 550 801 5.0E-26 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 4837 5131 1.1E-101 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1512 1807 5.6E-110 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 Gene3D G3DSA:3.90.180.10 5685 6021 6.1E-56 T 29-03-2018 SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 SUPERFAMILY SSF53901 2755 3132 1.5E-103 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 SMART SM00829 5710 6018 3.0E-148 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 Gene3D G3DSA:3.10.129.10 1875 2005 5.4E-8 T 29-03-2018 SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 Gene3D G3DSA:3.10.129.10 5211 5323 4.1E-7 T 29-03-2018 SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 ProSitePatterns PS00012 Phosphopantetheine attachment site. 6346 6361 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 SUPERFAMILY SSF51735 5817 5988 1.79E-34 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 SUPERFAMILY SSF53901 979 1349 2.02E-99 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 Pfam PF08659 KR domain 2375 2551 2.2E-52 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 Pfam PF08659 KR domain 3919 4097 1.3E-60 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 Pfam PF08659 KR domain 6029 6205 3.3E-56 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 SUPERFAMILY SSF47336 4203 4319 2.36E-23 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 SUPERFAMILY SSF55048 4957 5022 2.22E-11 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 SUPERFAMILY SSF47336 6313 6393 2.36E-20 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 SMART SM00825 Beta-ketoacyl synthase 2761 3187 1.8E-225 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 SMART SM00825 Beta-ketoacyl synthase 984 1407 3.8E-213 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 SMART SM00825 Beta-ketoacyl synthase 28 447 1.2E-171 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 SMART SM00825 Beta-ketoacyl synthase 4307 4733 5.2E-219 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 SMART SM00823 Phosphopantetheine attachment site 6319 6391 3.6E-30 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 SMART SM00823 Phosphopantetheine attachment site 4208 4280 3.0E-30 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 SMART SM00823 Phosphopantetheine attachment site 895 965 2.7E-14 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 SMART SM00823 Phosphopantetheine attachment site 2657 2729 9.6E-31 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 Gene3D G3DSA:3.30.70.250 1644 1691 1.3E-15 T 29-03-2018 SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 Gene3D G3DSA:3.40.47.10 974 1240 3.4E-84 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 Gene3D G3DSA:3.40.47.10 2757 3021 2.3E-88 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 Gene3D G3DSA:3.40.47.10 4303 4567 2.7E-83 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 Gene3D G3DSA:1.10.1200.10 852 972 1.6E-13 T 29-03-2018 SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 SUPERFAMILY SSF51735 5487 5678 2.64E-27 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 SUPERFAMILY SSF53901 24 389 3.35E-86 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 SUPERFAMILY SSF51735 6028 6246 6.72E-37 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 SUPERFAMILY SSF55048 1633 1698 5.49E-11 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 Gene3D G3DSA:3.40.47.10 4570 4731 3.1E-63 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 Gene3D G3DSA:3.40.47.10 1243 1405 1.0E-60 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 Gene3D G3DSA:3.40.47.10 281 445 1.7E-55 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 Gene3D G3DSA:3.40.47.10 3024 3185 2.9E-60 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 SUPERFAMILY SSF52151 3286 3411 5.23E-64 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 SUPERFAMILY SSF52151 3476 3574 5.23E-64 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 3017 3133 3.3E-42 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 4564 4680 5.8E-45 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1236 1353 5.5E-43 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 275 391 1.1E-38 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 Gene3D G3DSA:1.10.1200.10 6289 6399 7.5E-18 T 29-03-2018 SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 SUPERFAMILY SSF51735 2373 2609 2.2E-42 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 Gene3D G3DSA:3.40.47.10 29 279 2.6E-76 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 5736 5793 1.7E-7 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 SUPERFAMILY SSF51735 3916 4151 9.87E-49 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 Pfam PF00550 Phosphopantetheine attachment site 894 961 5.6E-8 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 Pfam PF00550 Phosphopantetheine attachment site 6321 6387 1.6E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 Pfam PF00550 Phosphopantetheine attachment site 4210 4276 1.8E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 Pfam PF00550 Phosphopantetheine attachment site 2659 2725 1.6E-9 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 SUPERFAMILY SSF47336 894 997 1.96E-15 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 SUPERFAMILY SSF51735 3698 3907 1.1E-40 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 982 1228 2.8E-84 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 28 266 1.1E-73 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2759 3009 5.6E-89 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4305 4555 4.2E-87 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 SUPERFAMILY SSF47336 2651 2773 1.96E-20 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 2922 2938 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 Gene3D G3DSA:3.30.70.250 4970 5012 2.0E-14 T 29-03-2018 SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 SUPERFAMILY SSF55048 3410 3475 1.57E-12 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 Gene3D G3DSA:3.40.366.10 4830 4969 1.1E-40 T 29-03-2018 SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 SMART SM01294 4209 4276 1.5E-7 T 29-03-2018 SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 SMART SM01294 6320 6387 1.2E-5 T 29-03-2018 SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 Gene3D G3DSA:3.40.366.10 1692 1807 6.4E-24 T 29-03-2018 SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 Gene3D G3DSA:3.40.366.10 3467 3588 8.1E-25 T 29-03-2018 SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 Gene3D G3DSA:3.40.366.10 5013 5133 3.7E-24 T 29-03-2018 SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 Pfam PF14765 Polyketide synthase dehydratase 1874 2163 6.3E-44 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 Pfam PF14765 Polyketide synthase dehydratase 5199 5480 3.1E-53 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 SUPERFAMILY SSF51735 2175 2361 3.5E-25 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4235 4250 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1356 1471 3.4E-12 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 394 510 2.3E-15 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 4683 4798 4.3E-14 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 3137 3250 1.0E-14 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 Gene3D G3DSA:3.30.70.250 3420 3466 6.6E-18 T 29-03-2018 SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 4468 4484 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 5845 5866 - T 29-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2684 2699 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 Pfam PF00698 Acyl transferase domain 3287 3602 2.3E-86 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 Pfam PF00698 Acyl transferase domain 550 697 2.0E-16 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 Pfam PF00698 Acyl transferase domain 4836 5149 2.6E-71 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 Pfam PF00698 Acyl transferase domain 1510 1825 1.9E-83 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 Pfam PF13602 Zinc-binding dehydrogenase 5896 6018 4.2E-12 T 29-03-2018 SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6029 6207 1.3E-51 T 29-03-2018 SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2375 2553 4.2E-49 T 29-03-2018 SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3919 4098 2.2E-62 T 29-03-2018 SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 SUPERFAMILY SSF53901 4303 4678 1.23E-101 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 SMART SM00826 5199 5361 1.0E-75 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 SMART SM00826 1874 2042 4.0E-59 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1141 1157 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 Gene3D G3DSA:3.40.366.10 1508 1643 8.9E-40 T 29-03-2018 SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 Gene3D G3DSA:3.40.366.10 3286 3419 9.9E-41 T 29-03-2018 SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 SUPERFAMILY SSF52151 5023 5119 5.23E-60 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 SUPERFAMILY SSF52151 4833 4959 5.23E-60 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 SUPERFAMILY SSF52151 1508 1634 9.94E-65 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 SUPERFAMILY SSF52151 1699 1794 9.94E-65 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 SUPERFAMILY SSF50129 5731 5850 7.39E-28 T 29-03-2018 IPR011032 GroES-like SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 SUPERFAMILY SSF52151 611 779 2.22E-48 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 SUPERFAMILY SSF52151 548 582 2.22E-48 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 Gene3D G3DSA:3.40.366.10 546 815 1.1E-56 T 29-03-2018 SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 Gene3D G3DSA:1.10.1200.10 2653 2756 3.5E-19 T 29-03-2018 SMALA_RS39115 9e502cc6de4b162684539df9cfd515ef 6509 Gene3D G3DSA:1.10.1200.10 4201 4302 1.3E-20 T 29-03-2018 SMALA_RS09125 16d85b913e67dec1c6d566c0e443612f 1481 Gene3D G3DSA:1.10.287.130 949 1011 4.2E-16 T 29-03-2018 SMALA_RS09125 16d85b913e67dec1c6d566c0e443612f 1481 SMART SM00388 947 1015 2.3E-21 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS09125 16d85b913e67dec1c6d566c0e443612f 1481 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 1063 1184 4.1E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS09125 16d85b913e67dec1c6d566c0e443612f 1481 Pfam PF00672 HAMP domain 593 637 2.8E-6 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMALA_RS09125 16d85b913e67dec1c6d566c0e443612f 1481 SUPERFAMILY SSF55874 1004 1187 6.02E-45 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS09125 16d85b913e67dec1c6d566c0e443612f 1481 Gene3D G3DSA:3.30.450.40 721 948 1.7E-25 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS09125 16d85b913e67dec1c6d566c0e443612f 1481 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1129 1139 1.3E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS09125 16d85b913e67dec1c6d566c0e443612f 1481 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1170 1183 1.3E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS09125 16d85b913e67dec1c6d566c0e443612f 1481 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1146 1164 1.3E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS09125 16d85b913e67dec1c6d566c0e443612f 1481 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1111 1125 1.3E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS09125 16d85b913e67dec1c6d566c0e443612f 1481 SUPERFAMILY SSF58104 610 734 9.42E-9 T 29-03-2018 SMALA_RS09125 16d85b913e67dec1c6d566c0e443612f 1481 SUPERFAMILY SSF55781 724 898 1.01E-25 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS09125 16d85b913e67dec1c6d566c0e443612f 1481 SMART SM00065 755 907 1.4E-5 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS09125 16d85b913e67dec1c6d566c0e443612f 1481 SUPERFAMILY SSF52172 1285 1408 1.42E-37 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS09125 16d85b913e67dec1c6d566c0e443612f 1481 Pfam PF00072 Response regulator receiver domain 1291 1403 6.0E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS09125 16d85b913e67dec1c6d566c0e443612f 1481 Pfam PF13185 GAF domain 754 897 1.9E-16 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS09125 16d85b913e67dec1c6d566c0e443612f 1481 Gene3D G3DSA:3.40.50.2300 1286 1410 2.5E-36 T 29-03-2018 SMALA_RS09125 16d85b913e67dec1c6d566c0e443612f 1481 SUPERFAMILY SSF58104 334 607 1.28E-19 T 29-03-2018 SMALA_RS09125 16d85b913e67dec1c6d566c0e443612f 1481 SUPERFAMILY SSF47384 934 1016 7.06E-19 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS09125 16d85b913e67dec1c6d566c0e443612f 1481 SMART SM00304 498 550 1.2E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMALA_RS09125 16d85b913e67dec1c6d566c0e443612f 1481 SMART SM00304 590 642 1.2E-8 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMALA_RS09125 16d85b913e67dec1c6d566c0e443612f 1481 SMART SM00304 125 182 3.0E-5 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMALA_RS09125 16d85b913e67dec1c6d566c0e443612f 1481 SMART SM00304 406 458 4.6E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMALA_RS09125 16d85b913e67dec1c6d566c0e443612f 1481 SMART SM00304 222 274 4.9E-8 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMALA_RS09125 16d85b913e67dec1c6d566c0e443612f 1481 SMART SM00304 682 734 3.3E-7 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMALA_RS09125 16d85b913e67dec1c6d566c0e443612f 1481 SMART SM00304 314 366 1.4E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMALA_RS09125 16d85b913e67dec1c6d566c0e443612f 1481 SMART SM00304 33 85 5.1 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMALA_RS09125 16d85b913e67dec1c6d566c0e443612f 1481 SUPERFAMILY SSF58104 190 330 1.52E-7 T 29-03-2018 SMALA_RS09125 16d85b913e67dec1c6d566c0e443612f 1481 SUPERFAMILY SSF58104 53 87 1.52E-7 T 29-03-2018 SMALA_RS09125 16d85b913e67dec1c6d566c0e443612f 1481 SMART SM00387 1062 1186 1.0E-37 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS09125 16d85b913e67dec1c6d566c0e443612f 1481 SMART SM00448 1289 1403 3.8E-36 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS09125 16d85b913e67dec1c6d566c0e443612f 1481 Gene3D G3DSA:3.30.565.10 1019 1190 1.3E-45 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS09125 16d85b913e67dec1c6d566c0e443612f 1481 Gene3D G3DSA:2.60.120.260 510 601 9.2E-23 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS09125 16d85b913e67dec1c6d566c0e443612f 1481 Gene3D G3DSA:2.60.120.260 602 694 3.3E-19 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS09125 16d85b913e67dec1c6d566c0e443612f 1481 Gene3D G3DSA:2.60.120.260 326 417 4.9E-24 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS09125 16d85b913e67dec1c6d566c0e443612f 1481 Gene3D G3DSA:2.60.120.260 418 509 1.6E-22 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS09125 16d85b913e67dec1c6d566c0e443612f 1481 Gene3D G3DSA:2.60.120.260 234 325 4.9E-23 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS09125 16d85b913e67dec1c6d566c0e443612f 1481 Gene3D G3DSA:2.60.120.260 128 233 3.9E-12 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS09125 16d85b913e67dec1c6d566c0e443612f 1481 Pfam PF00512 His Kinase A (phospho-acceptor) domain 948 1015 4.2E-18 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS12990 23f257836fbe5cda948f18c64820fe2f 88 SUPERFAMILY SSF46992 3 86 6.8E-28 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS12990 23f257836fbe5cda948f18c64820fe2f 88 TIGRFAM TIGR00029 S20: ribosomal protein bS20 2 86 6.8E-25 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS12990 23f257836fbe5cda948f18c64820fe2f 88 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 14 87 1.0E-11 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS12990 23f257836fbe5cda948f18c64820fe2f 88 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 16.808 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS12990 23f257836fbe5cda948f18c64820fe2f 88 Pfam PF01649 Ribosomal protein S20 2 83 1.6E-26 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS12990 23f257836fbe5cda948f18c64820fe2f 88 Gene3D G3DSA:1.20.58.110 1 88 5.9E-28 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS19805 c62d1e14631af4e0f4376766eb593100 292 SUPERFAMILY SSF144091 77 263 2.09E-45 T 29-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 SMALA_RS19805 c62d1e14631af4e0f4376766eb593100 292 Gene3D G3DSA:1.20.1540.10 77 259 6.6E-44 T 29-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 SMALA_RS19805 c62d1e14631af4e0f4376766eb593100 292 Pfam PF01694 Rhomboid family 124 257 1.2E-37 T 29-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 SMALA_RS11700 c292aa52ec5c91ebbb3d28950929487f 595 Pfam PF08388 Group II intron, maturase-specific domain 360 436 6.8E-20 T 29-03-2018 IPR013597 Group II intron, maturase-specific SMALA_RS11700 c292aa52ec5c91ebbb3d28950929487f 595 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 66 423 1.4E-102 T 29-03-2018 IPR030931 Group II intron reverse transcriptase/maturase SMALA_RS11700 c292aa52ec5c91ebbb3d28950929487f 595 SUPERFAMILY SSF56672 85 424 3.11E-47 T 29-03-2018 SMALA_RS11700 c292aa52ec5c91ebbb3d28950929487f 595 Gene3D G3DSA:3.30.70.270 146 341 1.6E-29 T 29-03-2018 SMALA_RS11700 c292aa52ec5c91ebbb3d28950929487f 595 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 121 341 1.4E-42 T 29-03-2018 IPR000477 Reverse transcriptase domain SMALA_RS11700 c292aa52ec5c91ebbb3d28950929487f 595 Pfam PF13655 N-terminal domain of reverse transcriptase 23 104 5.8E-29 T 29-03-2018 IPR025960 Reverse transcriptase, N-terminal domain SMALA_RS11700 c292aa52ec5c91ebbb3d28950929487f 595 Gene3D G3DSA:3.40.1800.10 493 590 1.8E-9 T 29-03-2018 SMALA_RS11700 c292aa52ec5c91ebbb3d28950929487f 595 Pfam PF01844 HNH endonuclease 545 578 1.3E-7 T 29-03-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 SMALA_RS13830 7a0ef9b573745335ae35798ae9a588fb 937 SMART SM00421 871 928 5.4E-19 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS13830 7a0ef9b573745335ae35798ae9a588fb 937 Pfam PF13191 AAA ATPase domain 12 164 2.5E-16 T 29-03-2018 SMALA_RS13830 7a0ef9b573745335ae35798ae9a588fb 937 SUPERFAMILY SSF46894 866 929 1.29E-15 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS13830 7a0ef9b573745335ae35798ae9a588fb 937 SUPERFAMILY SSF52540 4 235 4.75E-11 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS13830 7a0ef9b573745335ae35798ae9a588fb 937 ProSitePatterns PS00622 LuxR-type HTH domain signature. 888 915 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS13830 7a0ef9b573745335ae35798ae9a588fb 937 SMART SM00382 29 199 0.0031 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS13830 7a0ef9b573745335ae35798ae9a588fb 937 Gene3D G3DSA:1.25.40.10 455 644 3.7E-4 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS13830 7a0ef9b573745335ae35798ae9a588fb 937 Gene3D G3DSA:1.25.40.10 646 871 2.4E-21 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS13830 7a0ef9b573745335ae35798ae9a588fb 937 Gene3D G3DSA:1.10.10.10 872 936 1.4E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS13830 7a0ef9b573745335ae35798ae9a588fb 937 Pfam PF00196 Bacterial regulatory proteins, luxR family 873 924 2.9E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS13830 7a0ef9b573745335ae35798ae9a588fb 937 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 888 904 1.3E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS13830 7a0ef9b573745335ae35798ae9a588fb 937 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 874 888 1.3E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS13830 7a0ef9b573745335ae35798ae9a588fb 937 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 904 916 1.3E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS13830 7a0ef9b573745335ae35798ae9a588fb 937 Gene3D G3DSA:3.40.50.300 8 271 4.0E-10 T 29-03-2018 SMALA_RS13830 7a0ef9b573745335ae35798ae9a588fb 937 SUPERFAMILY SSF48452 795 831 5.31E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS13830 7a0ef9b573745335ae35798ae9a588fb 937 SUPERFAMILY SSF48452 689 765 5.31E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS40090 9be6a7e2ccc34c25813ae1b74d3aa315 346 SUPERFAMILY SSF51735 145 294 8.73E-26 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS40090 9be6a7e2ccc34c25813ae1b74d3aa315 346 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 24 129 3.9E-17 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS40090 9be6a7e2ccc34c25813ae1b74d3aa315 346 SUPERFAMILY SSF50129 2 180 4.72E-33 T 29-03-2018 IPR011032 GroES-like SMALA_RS40090 9be6a7e2ccc34c25813ae1b74d3aa315 346 Gene3D G3DSA:3.90.180.10 1 173 1.8E-30 T 29-03-2018 SMALA_RS40090 9be6a7e2ccc34c25813ae1b74d3aa315 346 Pfam PF00107 Zinc-binding dehydrogenase 181 301 9.5E-12 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMALA_RS40090 9be6a7e2ccc34c25813ae1b74d3aa315 346 Gene3D G3DSA:3.40.50.720 174 287 1.4E-16 T 29-03-2018 SMALA_RS40090 9be6a7e2ccc34c25813ae1b74d3aa315 346 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 61 75 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 SMALA_RS25105 3978d0203f56416d74e18aae465fba5d 394 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 284 290 - T 29-03-2018 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 SMALA_RS25105 3978d0203f56416d74e18aae465fba5d 394 SUPERFAMILY SSF51395 26 385 7.33E-84 T 29-03-2018 SMALA_RS25105 3978d0203f56416d74e18aae465fba5d 394 Pfam PF01070 FMN-dependent dehydrogenase 35 384 2.2E-111 T 29-03-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 SMALA_RS25105 3978d0203f56416d74e18aae465fba5d 394 PIRSF PIRSF000138 20 388 1.2E-111 T 29-03-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 SMALA_RS25105 3978d0203f56416d74e18aae465fba5d 394 Gene3D G3DSA:3.20.20.70 25 388 1.2E-93 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS25230 9f1900f4175b4a80b9886e746f4c877e 292 Gene3D G3DSA:3.10.310.10 127 267 1.7E-30 T 29-03-2018 SMALA_RS25230 9f1900f4175b4a80b9886e746f4c877e 292 SUPERFAMILY SSF54506 5 114 9.42E-20 T 29-03-2018 SMALA_RS25230 9f1900f4175b4a80b9886e746f4c877e 292 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 2 280 26.041 T 29-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 SMALA_RS25230 9f1900f4175b4a80b9886e746f4c877e 292 SUPERFAMILY SSF54506 153 275 4.51E-30 T 29-03-2018 SMALA_RS25230 9f1900f4175b4a80b9886e746f4c877e 292 Gene3D G3DSA:3.10.310.10 1 126 1.5E-27 T 29-03-2018 SMALA_RS25230 9f1900f4175b4a80b9886e746f4c877e 292 Pfam PF01678 Diaminopimelate epimerase 159 264 2.9E-17 T 29-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 SMALA_RS25230 9f1900f4175b4a80b9886e746f4c877e 292 Pfam PF01678 Diaminopimelate epimerase 5 115 1.3E-16 T 29-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 SMALA_RS25230 9f1900f4175b4a80b9886e746f4c877e 292 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 5 275 1.6E-48 T 29-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 SMALA_RS32900 4f07cc52b998e2319c3cb8ad1f4da639 201 TIGRFAM TIGR03800 PLP_synth_Pdx2: pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2 12 196 3.8E-81 T 29-03-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 SMALA_RS32900 4f07cc52b998e2319c3cb8ad1f4da639 201 Gene3D G3DSA:3.40.50.880 11 201 7.8E-46 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS32900 4f07cc52b998e2319c3cb8ad1f4da639 201 SUPERFAMILY SSF52317 11 199 4.35E-54 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS32900 4f07cc52b998e2319c3cb8ad1f4da639 201 ProSitePatterns PS01236 PdxT/SNO family family signature. 49 59 - T 29-03-2018 IPR021196 PdxT/SNO family, conserved site KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 SMALA_RS32900 4f07cc52b998e2319c3cb8ad1f4da639 201 Pfam PF01174 SNO glutamine amidotransferase family 14 198 5.3E-60 T 29-03-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 SMALA_RS32900 4f07cc52b998e2319c3cb8ad1f4da639 201 Hamap MF_01615 Pyridoxal 5'-phosphate synthase subunit PdxT [pdxT]. 12 197 38.51 T 29-03-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 SMALA_RS32900 4f07cc52b998e2319c3cb8ad1f4da639 201 PIRSF PIRSF005639 6 201 1.2E-74 T 29-03-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 SMALA_RS03905 492a94388133a68b8af99cb7ff2313ed 373 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 49 332 8.1E-44 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMALA_RS03905 492a94388133a68b8af99cb7ff2313ed 373 Gene3D G3DSA:3.40.50.1100 50 157 3.6E-22 T 29-03-2018 SMALA_RS03905 492a94388133a68b8af99cb7ff2313ed 373 SUPERFAMILY SSF53686 41 354 8.77E-69 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMALA_RS03905 492a94388133a68b8af99cb7ff2313ed 373 Gene3D G3DSA:3.40.50.1100 158 347 5.8E-36 T 29-03-2018 SMALA_RS36545 031256d11da0588e4f1e0d0353277a34 427 Gene3D G3DSA:3.40.47.10 1 271 5.6E-31 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS36545 031256d11da0588e4f1e0d0353277a34 427 Gene3D G3DSA:3.40.47.10 273 422 3.5E-13 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS36545 031256d11da0588e4f1e0d0353277a34 427 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 155 171 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS36545 031256d11da0588e4f1e0d0353277a34 427 SUPERFAMILY SSF53901 228 424 1.79E-33 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS36545 031256d11da0588e4f1e0d0353277a34 427 SUPERFAMILY SSF53901 1 264 1.47E-26 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS36545 031256d11da0588e4f1e0d0353277a34 427 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1 259 1.9E-10 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS36545 031256d11da0588e4f1e0d0353277a34 427 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 267 380 4.7E-9 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS36545 031256d11da0588e4f1e0d0353277a34 427 SMART SM00825 Beta-ketoacyl synthase 1 404 5.0E-5 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS04535 3cecbcbfe7f68f786e1f6679dc20c135 154 Gene3D G3DSA:3.30.565.10 11 151 3.4E-13 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS04535 3cecbcbfe7f68f786e1f6679dc20c135 154 SUPERFAMILY SSF55874 43 135 3.73E-9 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS41785 c7d5e607321d623f4b19565e9e6f10e5 304 SUPERFAMILY SSF46689 249 299 2.51E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS41785 c7d5e607321d623f4b19565e9e6f10e5 304 SMART SM00342 213 295 9.9E-24 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS41785 c7d5e607321d623f4b19565e9e6f10e5 304 Pfam PF12833 Helix-turn-helix domain 219 297 1.6E-19 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS41785 c7d5e607321d623f4b19565e9e6f10e5 304 Gene3D G3DSA:1.10.10.60 192 249 0.019 T 29-03-2018 SMALA_RS41785 c7d5e607321d623f4b19565e9e6f10e5 304 Pfam PF14525 AraC-binding-like domain 10 184 3.5E-19 T 29-03-2018 IPR035418 Transcription regulator HTH, AraC- type, ligand binding domain-like SMALA_RS41785 c7d5e607321d623f4b19565e9e6f10e5 304 Gene3D G3DSA:1.10.10.60 250 303 3.6E-15 T 29-03-2018 SMALA_RS14040 306a74c6cb2476ad11754f9a7bd81aac 385 SUPERFAMILY SSF51735 6 170 2.84E-39 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS14040 306a74c6cb2476ad11754f9a7bd81aac 385 SUPERFAMILY SSF55347 145 282 1.05E-29 T 29-03-2018 SMALA_RS14040 306a74c6cb2476ad11754f9a7bd81aac 385 Gene3D G3DSA:3.40.50.720 1 158 2.1E-36 T 29-03-2018 SMALA_RS14040 306a74c6cb2476ad11754f9a7bd81aac 385 Gene3D G3DSA:3.30.360.10 159 355 7.7E-40 T 29-03-2018 SMALA_RS14040 306a74c6cb2476ad11754f9a7bd81aac 385 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 148 254 1.9E-12 T 29-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 SMALA_RS14040 306a74c6cb2476ad11754f9a7bd81aac 385 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 9 129 1.6E-23 T 29-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 SMALA_RS18500 5aa05bceddf5fecf9e4dd33f3093ad96 946 Gene3D G3DSA:1.10.460.10 155 374 5.7E-44 T 29-03-2018 SMALA_RS18500 5aa05bceddf5fecf9e4dd33f3093ad96 946 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 15 660 9.8E-240 T 29-03-2018 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 SMALA_RS18500 5aa05bceddf5fecf9e4dd33f3093ad96 946 SMART SM00437 289 556 2.2E-119 T 29-03-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 SMALA_RS18500 5aa05bceddf5fecf9e4dd33f3093ad96 946 Gene3D G3DSA:2.70.20.10 375 495 1.4E-39 T 29-03-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 SMALA_RS18500 5aa05bceddf5fecf9e4dd33f3093ad96 946 Hamap MF_00952 DNA topoisomerase 1 [topA]. 13 780 55.211 T 29-03-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 SMALA_RS18500 5aa05bceddf5fecf9e4dd33f3093ad96 946 Pfam PF01131 DNA topoisomerase 150 593 1.2E-127 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 SMALA_RS18500 5aa05bceddf5fecf9e4dd33f3093ad96 946 SUPERFAMILY SSF56712 13 597 1.31E-178 T 29-03-2018 IPR023405 DNA topoisomerase, type IA, core domain SMALA_RS18500 5aa05bceddf5fecf9e4dd33f3093ad96 946 Pfam PF01751 Toprim domain 15 135 1.2E-27 T 29-03-2018 IPR006171 TOPRIM domain SMALA_RS18500 5aa05bceddf5fecf9e4dd33f3093ad96 946 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 326 340 - T 29-03-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 SMALA_RS18500 5aa05bceddf5fecf9e4dd33f3093ad96 946 Gene3D G3DSA:1.10.460.10 496 598 2.5E-20 T 29-03-2018 SMALA_RS18500 5aa05bceddf5fecf9e4dd33f3093ad96 946 SMART SM00436 126 214 4.0E-46 T 29-03-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 SMALA_RS18500 5aa05bceddf5fecf9e4dd33f3093ad96 946 SMART SM00493 13 126 4.8E-35 T 29-03-2018 IPR006171 TOPRIM domain SMALA_RS18500 5aa05bceddf5fecf9e4dd33f3093ad96 946 Gene3D G3DSA:3.40.50.140 12 154 6.1E-41 T 29-03-2018 SMALA_RS18500 5aa05bceddf5fecf9e4dd33f3093ad96 946 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 408 424 3.3E-33 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 SMALA_RS18500 5aa05bceddf5fecf9e4dd33f3093ad96 946 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 100 113 3.3E-33 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 SMALA_RS18500 5aa05bceddf5fecf9e4dd33f3093ad96 946 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 519 533 3.3E-33 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 SMALA_RS18500 5aa05bceddf5fecf9e4dd33f3093ad96 946 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 184 202 3.3E-33 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 SMALA_RS18500 5aa05bceddf5fecf9e4dd33f3093ad96 946 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 331 340 3.3E-33 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 SMALA_RS18500 5aa05bceddf5fecf9e4dd33f3093ad96 946 Pfam PF13368 Topoisomerase C-terminal repeat 701 764 1.1E-14 T 29-03-2018 IPR025589 Topoisomerase C-terminal repeat SMALA_RS18500 5aa05bceddf5fecf9e4dd33f3093ad96 946 Pfam PF13368 Topoisomerase C-terminal repeat 641 693 8.1E-6 T 29-03-2018 IPR025589 Topoisomerase C-terminal repeat SMALA_RS18500 5aa05bceddf5fecf9e4dd33f3093ad96 946 Pfam PF13368 Topoisomerase C-terminal repeat 769 821 1.5E-15 T 29-03-2018 IPR025589 Topoisomerase C-terminal repeat SMALA_RS18500 5aa05bceddf5fecf9e4dd33f3093ad96 946 Pfam PF13368 Topoisomerase C-terminal repeat 834 886 5.8E-20 T 29-03-2018 IPR025589 Topoisomerase C-terminal repeat SMALA_RS03630 d1decd44dc5dd730c65a9622a125d79d 502 Gene3D G3DSA:1.25.40.10 222 480 8.0E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS03630 d1decd44dc5dd730c65a9622a125d79d 502 SUPERFAMILY SSF48452 235 434 7.44E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS22655 27b405bfccce9a9f597d58ffa6b18a8b 73 SMART SM00316 5 73 6.0E-5 T 29-03-2018 IPR022967 RNA-binding domain, S1 SMALA_RS22655 27b405bfccce9a9f597d58ffa6b18a8b 73 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 2 73 26.761 T 29-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 SMALA_RS22655 27b405bfccce9a9f597d58ffa6b18a8b 73 Pfam PF01176 Translation initiation factor 1A / IF-1 8 71 3.5E-29 T 29-03-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 SMALA_RS22655 27b405bfccce9a9f597d58ffa6b18a8b 73 Gene3D G3DSA:2.40.50.140 1 73 1.4E-37 T 29-03-2018 SMALA_RS22655 27b405bfccce9a9f597d58ffa6b18a8b 73 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 4 72 6.4E-38 T 29-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 SMALA_RS22655 27b405bfccce9a9f597d58ffa6b18a8b 73 SUPERFAMILY SSF50249 4 72 8.32E-28 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMALA_RS36800 355bd94688686976ddba895949ed833c 122 SUPERFAMILY SSF52833 2 118 7.16E-27 T 29-03-2018 IPR012336 Thioredoxin-like fold SMALA_RS36800 355bd94688686976ddba895949ed833c 122 Pfam PF03960 ArsC family 54 115 2.9E-10 T 29-03-2018 IPR006660 Arsenate reductase-like SMALA_RS36800 355bd94688686976ddba895949ed833c 122 Gene3D G3DSA:3.40.30.10 1 117 1.2E-31 T 29-03-2018 SMALA_RS32280 c159efa0af1e11672de044fb87f3d641 255 Pfam PF13354 Beta-lactamase enzyme family 89 178 4.8E-7 T 29-03-2018 SMALA_RS32280 c159efa0af1e11672de044fb87f3d641 255 Gene3D G3DSA:3.40.710.10 17 255 2.5E-15 T 29-03-2018 SMALA_RS32280 c159efa0af1e11672de044fb87f3d641 255 SUPERFAMILY SSF56601 21 234 1.65E-27 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMALA_RS26420 98f4c6aa2edb89c432aabeaa9a561c8d 216 SUPERFAMILY SSF55486 74 201 2.09E-31 T 29-03-2018 SMALA_RS26420 98f4c6aa2edb89c432aabeaa9a561c8d 216 Pfam PF02031 Streptomyces extracellular neutral proteinase (M7) family 73 204 1.2E-78 T 29-03-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 SMALA_RS26420 98f4c6aa2edb89c432aabeaa9a561c8d 216 Gene3D G3DSA:3.40.390.10 73 204 4.4E-21 T 29-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 SMALA_RS26420 98f4c6aa2edb89c432aabeaa9a561c8d 216 ProDom PD016028 PROTEASE METALLOPROTEASE EXTRACELLULAR NEUTRAL SMALL METAL-BINDING ZINC HYDROLASE SNAPALYSIN ZYMOGEN 84 204 9.0E-58 T 29-03-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 SMALA_RS26420 98f4c6aa2edb89c432aabeaa9a561c8d 216 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 162 186 2.2E-62 T 29-03-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 SMALA_RS26420 98f4c6aa2edb89c432aabeaa9a561c8d 216 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 112 136 2.2E-62 T 29-03-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 SMALA_RS26420 98f4c6aa2edb89c432aabeaa9a561c8d 216 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 189 203 2.2E-62 T 29-03-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 SMALA_RS26420 98f4c6aa2edb89c432aabeaa9a561c8d 216 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 80 106 2.2E-62 T 29-03-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 SMALA_RS26420 98f4c6aa2edb89c432aabeaa9a561c8d 216 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 137 161 2.2E-62 T 29-03-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 SMALA_RS26420 98f4c6aa2edb89c432aabeaa9a561c8d 216 PIRSF PIRSF016573 1 216 2.3E-100 T 29-03-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 SMALA_RS40515 f1531b341ffa7e0981188df481f5baaf 248 Pfam PF00486 Transcriptional regulatory protein, C terminal 158 239 7.3E-21 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS40515 f1531b341ffa7e0981188df481f5baaf 248 Gene3D G3DSA:1.10.10.10 129 244 1.1E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS40515 f1531b341ffa7e0981188df481f5baaf 248 Gene3D G3DSA:3.40.50.2300 2 128 2.8E-31 T 29-03-2018 SMALA_RS40515 f1531b341ffa7e0981188df481f5baaf 248 SMART SM00448 10 121 2.7E-33 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS40515 f1531b341ffa7e0981188df481f5baaf 248 Pfam PF00072 Response regulator receiver domain 12 121 1.7E-23 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS40515 f1531b341ffa7e0981188df481f5baaf 248 SMART SM00862 157 239 2.9E-20 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS40515 f1531b341ffa7e0981188df481f5baaf 248 SUPERFAMILY SSF52172 11 189 1.28E-35 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS25225 72dcb24d0188881fecd3eaf04e9f085c 686 SUPERFAMILY SSF53706 3 566 1.27E-156 T 29-03-2018 SMALA_RS25225 72dcb24d0188881fecd3eaf04e9f085c 686 Gene3D G3DSA:3.40.228.10 171 253 2.6E-23 T 29-03-2018 SMALA_RS25225 72dcb24d0188881fecd3eaf04e9f085c 686 Gene3D G3DSA:2.40.40.20 540 686 9.0E-29 T 29-03-2018 SMALA_RS25225 72dcb24d0188881fecd3eaf04e9f085c 686 SUPERFAMILY SSF50692 557 682 4.29E-33 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain SMALA_RS25225 72dcb24d0188881fecd3eaf04e9f085c 686 Gene3D G3DSA:2.20.25.90 1 60 4.8E-15 T 29-03-2018 SMALA_RS25225 72dcb24d0188881fecd3eaf04e9f085c 686 Pfam PF00384 Molybdopterin oxidoreductase 59 467 5.7E-50 T 29-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS25225 72dcb24d0188881fecd3eaf04e9f085c 686 Gene3D G3DSA:3.40.50.740 254 517 3.5E-43 T 29-03-2018 SMALA_RS25225 72dcb24d0188881fecd3eaf04e9f085c 686 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 7 53 1.3E-8 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS25225 72dcb24d0188881fecd3eaf04e9f085c 686 Gene3D G3DSA:3.40.50.740 61 170 9.7E-17 T 29-03-2018 SMALA_RS25225 72dcb24d0188881fecd3eaf04e9f085c 686 SMART SM00926 1 56 9.4E-15 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS25225 72dcb24d0188881fecd3eaf04e9f085c 686 Pfam PF01568 Molydopterin dinucleotide binding domain 566 673 2.2E-23 T 29-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 SMALA_RS39625 916bfd53540ce3305c9a7dea0a6598d5 296 Gene3D G3DSA:1.10.10.10 1 83 3.5E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS39625 916bfd53540ce3305c9a7dea0a6598d5 296 SUPERFAMILY SSF53850 89 291 1.51E-34 T 29-03-2018 SMALA_RS39625 916bfd53540ce3305c9a7dea0a6598d5 296 Gene3D G3DSA:3.40.190.10 178 263 3.7E-16 T 29-03-2018 SMALA_RS39625 916bfd53540ce3305c9a7dea0a6598d5 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 1.4E-17 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS39625 916bfd53540ce3305c9a7dea0a6598d5 296 Pfam PF03466 LysR substrate binding domain 88 280 9.3E-34 T 29-03-2018 IPR005119 LysR, substrate-binding SMALA_RS39625 916bfd53540ce3305c9a7dea0a6598d5 296 SUPERFAMILY SSF46785 2 110 1.09E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS39625 916bfd53540ce3305c9a7dea0a6598d5 296 Gene3D G3DSA:3.40.190.10 88 177 1.5E-23 T 29-03-2018 SMALA_RS29260 80347cb2fbd9dee50cfb9de1000c8d9c 511 SUPERFAMILY SSF55874 200 328 6.29E-13 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS29260 80347cb2fbd9dee50cfb9de1000c8d9c 511 Gene3D G3DSA:3.30.565.10 25 327 8.2E-13 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS30930 deb7e968f1dedb563b79d0deb6715273 239 Gene3D G3DSA:3.40.50.150 2 228 9.6E-16 T 29-03-2018 SMALA_RS30930 deb7e968f1dedb563b79d0deb6715273 239 SUPERFAMILY SSF53335 8 157 5.83E-19 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS30930 deb7e968f1dedb563b79d0deb6715273 239 Pfam PF13649 Methyltransferase domain 52 146 3.0E-9 T 29-03-2018 SMALA_RS33330 31b762b097d5788be1122a23939bd2ba 369 Gene3D G3DSA:3.20.20.70 163 365 2.3E-23 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS33330 31b762b097d5788be1122a23939bd2ba 369 Pfam PF00571 CBS domain 284 333 2.2E-4 T 29-03-2018 IPR000644 CBS domain SMALA_RS33330 31b762b097d5788be1122a23939bd2ba 369 Pfam PF00571 CBS domain 226 271 5.2E-4 T 29-03-2018 IPR000644 CBS domain SMALA_RS33330 31b762b097d5788be1122a23939bd2ba 369 SUPERFAMILY SSF54631 205 335 1.39E-21 T 29-03-2018 SMALA_RS33330 31b762b097d5788be1122a23939bd2ba 369 SMART SM00116 225 273 3.2 T 29-03-2018 IPR000644 CBS domain SMALA_RS33330 31b762b097d5788be1122a23939bd2ba 369 SMART SM00116 285 333 2.1 T 29-03-2018 IPR000644 CBS domain SMALA_RS33330 31b762b097d5788be1122a23939bd2ba 369 Pfam PF01595 Domain of unknown function DUF21 8 200 2.6E-43 T 29-03-2018 IPR002550 Domain of unknown function DUF21 SMALA_RS13910 44a5c57731cb95d7b1792c86ae9335cd 69 Gene3D G3DSA:1.10.1660.10 1 66 3.7E-9 T 29-03-2018 SMALA_RS13910 44a5c57731cb95d7b1792c86ae9335cd 69 SUPERFAMILY SSF46955 6 56 1.79E-8 T 29-03-2018 IPR009061 Putative DNA-binding domain SMALA_RS13910 44a5c57731cb95d7b1792c86ae9335cd 69 Pfam PF13411 MerR HTH family regulatory protein 9 47 3.8E-6 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS28645 4d7090b871714db8b67752b528b5265a 749 Gene3D G3DSA:3.30.300.20 557 622 1.7E-14 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta SMALA_RS28645 4d7090b871714db8b67752b528b5265a 749 Gene3D G3DSA:1.10.10.400 278 340 3.3E-21 T 29-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 SMALA_RS28645 4d7090b871714db8b67752b528b5265a 749 SMART SM00322 579 643 7.6E-12 T 29-03-2018 IPR004087 K Homology domain GO:0003676 SMALA_RS28645 4d7090b871714db8b67752b528b5265a 749 SUPERFAMILY SSF55666 152 260 3.62E-29 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 SMALA_RS28645 4d7090b871714db8b67752b528b5265a 749 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 267 343 3.5E-16 T 29-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 SMALA_RS28645 4d7090b871714db8b67752b528b5265a 749 Pfam PF00013 KH domain 583 639 5.2E-11 T 29-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 SMALA_RS28645 4d7090b871714db8b67752b528b5265a 749 Pfam PF00575 S1 RNA binding domain 648 718 5.5E-13 T 29-03-2018 IPR003029 S1 domain GO:0003676 SMALA_RS28645 4d7090b871714db8b67752b528b5265a 749 SUPERFAMILY SSF46915 264 344 5.49E-17 T 29-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 SMALA_RS28645 4d7090b871714db8b67752b528b5265a 749 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 17 720 1.9E-261 T 29-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 SMALA_RS28645 4d7090b871714db8b67752b528b5265a 749 SUPERFAMILY SSF54791 576 688 2.18E-19 T 29-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 SMALA_RS28645 4d7090b871714db8b67752b528b5265a 749 PIRSF PIRSF005499 7 749 1.5E-283 T 29-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 SMALA_RS28645 4d7090b871714db8b67752b528b5265a 749 SUPERFAMILY SSF55666 474 573 1.66E-24 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 SMALA_RS28645 4d7090b871714db8b67752b528b5265a 749 Gene3D G3DSA:2.40.50.140 643 722 3.9E-17 T 29-03-2018 SMALA_RS28645 4d7090b871714db8b67752b528b5265a 749 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 9 726 26.892 T 29-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 SMALA_RS28645 4d7090b871714db8b67752b528b5265a 749 TIGRFAM TIGR02696 pppGpp_PNP: guanosine pentaphosphate synthetase I/polyribonucleotide nucleotidyltransferase 5 722 0.0 T 29-03-2018 IPR014069 Guanosine pentaphosphate synthetase I/polyribonucleotide nucleotidyltransferase GO:0004654|GO:0005737|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 SMALA_RS28645 4d7090b871714db8b67752b528b5265a 749 Gene3D G3DSA:3.30.230.70 341 556 1.7E-50 T 29-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 SMALA_RS28645 4d7090b871714db8b67752b528b5265a 749 SUPERFAMILY SSF54211 321 492 4.81E-42 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SMALA_RS28645 4d7090b871714db8b67752b528b5265a 749 SUPERFAMILY SSF54211 6 151 6.58E-46 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SMALA_RS28645 4d7090b871714db8b67752b528b5265a 749 Gene3D G3DSA:3.30.230.70 18 277 1.1E-48 T 29-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 SMALA_RS28645 4d7090b871714db8b67752b528b5265a 749 Pfam PF01138 3' exoribonuclease family, domain 1 20 151 2.2E-17 T 29-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 SMALA_RS28645 4d7090b871714db8b67752b528b5265a 749 Pfam PF01138 3' exoribonuclease family, domain 1 348 480 1.2E-14 T 29-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 SMALA_RS28645 4d7090b871714db8b67752b528b5265a 749 SMART SM00316 649 723 2.7E-18 T 29-03-2018 IPR022967 RNA-binding domain, S1 SMALA_RS33295 f481943e25ee4ceeb9d792d045b34050 210 Pfam PF00677 Lumazine binding domain 103 187 2.2E-25 T 29-03-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 SMALA_RS33295 f481943e25ee4ceeb9d792d045b34050 210 Pfam PF00677 Lumazine binding domain 3 89 6.8E-23 T 29-03-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 SMALA_RS33295 f481943e25ee4ceeb9d792d045b34050 210 Gene3D G3DSA:2.40.30.20 97 194 8.5E-35 T 29-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMALA_RS33295 f481943e25ee4ceeb9d792d045b34050 210 Gene3D G3DSA:2.40.30.20 1 96 6.5E-27 T 29-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMALA_RS33295 f481943e25ee4ceeb9d792d045b34050 210 SUPERFAMILY SSF63380 96 199 4.0E-33 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 SMALA_RS33295 f481943e25ee4ceeb9d792d045b34050 210 PIRSF PIRSF000498 1 210 2.3E-70 T 29-03-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 SMALA_RS33295 f481943e25ee4ceeb9d792d045b34050 210 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 2 204 6.5E-61 T 29-03-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 SMALA_RS33295 f481943e25ee4ceeb9d792d045b34050 210 SUPERFAMILY SSF63380 2 91 3.06E-23 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 SMALA_RS18775 c2c99d6e149c54aa48baba32ee5442ad 426 Pfam PF01842 ACT domain 272 336 4.1E-9 T 29-03-2018 IPR002912 ACT domain SMALA_RS18775 c2c99d6e149c54aa48baba32ee5442ad 426 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 2 410 6.0E-125 T 29-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 SMALA_RS18775 c2c99d6e149c54aa48baba32ee5442ad 426 Gene3D G3DSA:3.30.70.260 341 417 4.5E-19 T 29-03-2018 SMALA_RS18775 c2c99d6e149c54aa48baba32ee5442ad 426 Pfam PF13840 ACT domain 345 406 8.3E-12 T 29-03-2018 IPR027795 GATS-like ACT domain SMALA_RS18775 c2c99d6e149c54aa48baba32ee5442ad 426 SUPERFAMILY SSF55021 338 412 8.39E-21 T 29-03-2018 SMALA_RS18775 c2c99d6e149c54aa48baba32ee5442ad 426 PIRSF PIRSF000726 59 418 1.3E-125 T 29-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 SMALA_RS18775 c2c99d6e149c54aa48baba32ee5442ad 426 PIRSF PIRSF000726 1 62 3.3E-20 T 29-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 SMALA_RS18775 c2c99d6e149c54aa48baba32ee5442ad 426 SUPERFAMILY SSF55021 254 335 3.5E-19 T 29-03-2018 SMALA_RS18775 c2c99d6e149c54aa48baba32ee5442ad 426 SUPERFAMILY SSF53633 4 243 8.77E-74 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase SMALA_RS18775 c2c99d6e149c54aa48baba32ee5442ad 426 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 29-03-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 SMALA_RS18775 c2c99d6e149c54aa48baba32ee5442ad 426 Gene3D G3DSA:3.40.1160.10 1 235 7.7E-72 T 29-03-2018 SMALA_RS18775 c2c99d6e149c54aa48baba32ee5442ad 426 Pfam PF00696 Amino acid kinase family 3 231 3.8E-54 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase SMALA_RS18775 c2c99d6e149c54aa48baba32ee5442ad 426 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 64 410 1.9E-116 T 29-03-2018 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 SMALA_RS18775 c2c99d6e149c54aa48baba32ee5442ad 426 Gene3D G3DSA:3.30.70.260 236 340 2.6E-24 T 29-03-2018 SMALA_RS11620 3a920e2168c903f21b3825e78ed02f88 410 Pfam PF03129 Anticodon binding domain 309 383 5.0E-8 T 29-03-2018 IPR004154 Anticodon-binding SMALA_RS11620 3a920e2168c903f21b3825e78ed02f88 410 Gene3D G3DSA:3.30.930.10 1 294 4.2E-86 T 29-03-2018 SMALA_RS11620 3a920e2168c903f21b3825e78ed02f88 410 SUPERFAMILY SSF55681 3 294 1.16E-80 T 29-03-2018 SMALA_RS11620 3a920e2168c903f21b3825e78ed02f88 410 PRINTS PR01047 Threonyl-tRNA synthetase signature 128 151 2.4E-45 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 SMALA_RS11620 3a920e2168c903f21b3825e78ed02f88 410 PRINTS PR01047 Threonyl-tRNA synthetase signature 302 314 2.4E-45 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 SMALA_RS11620 3a920e2168c903f21b3825e78ed02f88 410 PRINTS PR01047 Threonyl-tRNA synthetase signature 275 288 2.4E-45 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 SMALA_RS11620 3a920e2168c903f21b3825e78ed02f88 410 PRINTS PR01047 Threonyl-tRNA synthetase signature 95 123 2.4E-45 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 SMALA_RS11620 3a920e2168c903f21b3825e78ed02f88 410 PRINTS PR01047 Threonyl-tRNA synthetase signature 232 260 2.4E-45 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 SMALA_RS11620 3a920e2168c903f21b3825e78ed02f88 410 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 90 296 6.6E-27 T 29-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMALA_RS11620 3a920e2168c903f21b3825e78ed02f88 410 SUPERFAMILY SSF52954 297 408 1.25E-18 T 29-03-2018 IPR004154 Anticodon-binding SMALA_RS11620 3a920e2168c903f21b3825e78ed02f88 410 Gene3D G3DSA:3.40.50.800 295 401 2.2E-15 T 29-03-2018 IPR004154 Anticodon-binding SMALA_RS11620 3a920e2168c903f21b3825e78ed02f88 410 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 3 388 3.8E-129 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 SMALA_RS40145 c904728d87639fba3b5cefbe2d8f76a6 259 SMART SM00382 46 217 3.7E-18 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS40145 c904728d87639fba3b5cefbe2d8f76a6 259 SUPERFAMILY SSF52540 23 218 2.01E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS40145 c904728d87639fba3b5cefbe2d8f76a6 259 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS40145 c904728d87639fba3b5cefbe2d8f76a6 259 Gene3D G3DSA:3.40.50.300 10 224 3.5E-54 T 29-03-2018 SMALA_RS40145 c904728d87639fba3b5cefbe2d8f76a6 259 Pfam PF00005 ABC transporter 37 167 3.4E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS19390 d7e1a135e78a7a3c2ed09b85280d466c 302 Gene3D G3DSA:3.20.20.30 15 273 3.5E-61 T 29-03-2018 SMALA_RS19390 d7e1a135e78a7a3c2ed09b85280d466c 302 SUPERFAMILY SSF51679 14 281 6.93E-56 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS19390 d7e1a135e78a7a3c2ed09b85280d466c 302 Pfam PF00296 Luciferase-like monooxygenase 18 238 1.0E-46 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS42610 8d128fc2e0fb0b6fcb00797313d5697f 330 Gene3D G3DSA:3.20.20.30 9 329 5.8E-48 T 29-03-2018 SMALA_RS42610 8d128fc2e0fb0b6fcb00797313d5697f 330 SUPERFAMILY SSF51679 12 328 3.39E-44 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS42610 8d128fc2e0fb0b6fcb00797313d5697f 330 Pfam PF00296 Luciferase-like monooxygenase 19 304 1.7E-39 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS18770 2ffe549d568a9b0ebc7618ecadf09efc 363 Gene3D G3DSA:3.40.50.720 8 146 3.9E-34 T 29-03-2018 SMALA_RS18770 2ffe549d568a9b0ebc7618ecadf09efc 363 PIRSF PIRSF000148 12 357 2.0E-115 T 29-03-2018 SMALA_RS18770 2ffe549d568a9b0ebc7618ecadf09efc 363 SUPERFAMILY SSF51735 14 165 2.77E-44 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS18770 2ffe549d568a9b0ebc7618ecadf09efc 363 Gene3D G3DSA:3.30.360.10 147 336 5.2E-84 T 29-03-2018 SMALA_RS18770 2ffe549d568a9b0ebc7618ecadf09efc 363 SMART SM00859 14 129 2.2E-33 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 SMALA_RS18770 2ffe549d568a9b0ebc7618ecadf09efc 363 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 150 339 1.3E-46 T 29-03-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 SMALA_RS18770 2ffe549d568a9b0ebc7618ecadf09efc 363 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 15 353 1.2E-116 T 29-03-2018 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 SMALA_RS18770 2ffe549d568a9b0ebc7618ecadf09efc 363 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 15 126 3.9E-27 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 SMALA_RS18770 2ffe549d568a9b0ebc7618ecadf09efc 363 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 12 353 33.106 T 29-03-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 SMALA_RS18770 2ffe549d568a9b0ebc7618ecadf09efc 363 SUPERFAMILY SSF55347 138 340 4.27E-65 T 29-03-2018 SMALA_RS18200 45dc45a25b1d8261ddf4dd433d4def08 287 Pfam PF13560 Helix-turn-helix domain 16 77 5.8E-14 T 29-03-2018 SMALA_RS18200 45dc45a25b1d8261ddf4dd433d4def08 287 SUPERFAMILY SSF47413 13 71 2.45E-7 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS18200 45dc45a25b1d8261ddf4dd433d4def08 287 SMART SM00530 19 74 2.7E-5 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS18200 45dc45a25b1d8261ddf4dd433d4def08 287 Gene3D G3DSA:1.10.260.40 8 106 6.1E-12 T 29-03-2018 SMALA_RS38660 91acf4014017f28b8a0ab58e0c1f8fea 188 SUPERFAMILY SSF161098 46 180 1.44E-31 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS38660 91acf4014017f28b8a0ab58e0c1f8fea 188 Gene3D G3DSA:1.10.3720.10 27 185 5.9E-28 T 29-03-2018 SMALA_RS38660 91acf4014017f28b8a0ab58e0c1f8fea 188 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 51 178 2.3E-12 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS17150 7eaf1159aee296e15bea441f408e26f5 395 PIRSF PIRSF000138 15 395 7.2E-119 T 29-03-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 SMALA_RS17150 7eaf1159aee296e15bea441f408e26f5 395 Pfam PF01070 FMN-dependent dehydrogenase 45 394 2.5E-121 T 29-03-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 SMALA_RS17150 7eaf1159aee296e15bea441f408e26f5 395 Gene3D G3DSA:3.20.20.70 36 395 2.7E-100 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS17150 7eaf1159aee296e15bea441f408e26f5 395 SUPERFAMILY SSF51395 38 393 5.86E-90 T 29-03-2018 SMALA_RS17150 7eaf1159aee296e15bea441f408e26f5 395 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 292 298 - T 29-03-2018 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 SMALA_RS15450 abecd665f100eae537716a4fddab23e3 755 Gene3D G3DSA:3.20.20.80 237 603 2.1E-121 T 29-03-2018 SMALA_RS15450 abecd665f100eae537716a4fddab23e3 755 Pfam PF13802 Galactose mutarotase-like 158 216 1.0E-16 T 29-03-2018 IPR025887 Glycoside hydrolase family 31, N-terminal domain SMALA_RS15450 abecd665f100eae537716a4fddab23e3 755 SUPERFAMILY SSF51445 246 582 1.77E-94 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS15450 abecd665f100eae537716a4fddab23e3 755 SUPERFAMILY SSF117125 664 739 1.06E-15 T 29-03-2018 SMALA_RS15450 abecd665f100eae537716a4fddab23e3 755 SUPERFAMILY SSF74650 1 245 2.26E-59 T 29-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 SMALA_RS15450 abecd665f100eae537716a4fddab23e3 755 Gene3D G3DSA:2.60.40.1180 664 753 6.5E-23 T 29-03-2018 SMALA_RS15450 abecd665f100eae537716a4fddab23e3 755 Gene3D G3DSA:2.60.40.1180 604 663 1.4E-14 T 29-03-2018 SMALA_RS15450 abecd665f100eae537716a4fddab23e3 755 SUPERFAMILY SSF51011 584 662 3.52E-18 T 29-03-2018 SMALA_RS15450 abecd665f100eae537716a4fddab23e3 755 Pfam PF01055 Glycosyl hydrolases family 31 238 667 9.1E-122 T 29-03-2018 IPR000322 Glycoside hydrolase family 31 GO:0004553|GO:0005975 SMALA_RS15450 abecd665f100eae537716a4fddab23e3 755 Gene3D G3DSA:2.60.40.1760 1 236 4.4E-55 T 29-03-2018 SMALA_RS24765 f5ab25775ab01a57e8abcbcc3a6f759a 174 Gene3D G3DSA:1.10.10.10 1 91 2.6E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS24765 f5ab25775ab01a57e8abcbcc3a6f759a 174 Pfam PF03551 Transcriptional regulator PadR-like family 7 77 1.1E-14 T 29-03-2018 IPR005149 Transcription regulator PadR, N-terminal SMALA_RS24765 f5ab25775ab01a57e8abcbcc3a6f759a 174 SUPERFAMILY SSF46785 3 167 2.73E-35 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS31375 4f8878acdf0ab4db025d29a3a9659889 471 Gene3D G3DSA:2.60.120.560 279 467 3.4E-50 T 29-03-2018 SMALA_RS31375 4f8878acdf0ab4db025d29a3a9659889 471 SUPERFAMILY SSF52317 54 274 2.08E-49 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS31375 4f8878acdf0ab4db025d29a3a9659889 471 Gene3D G3DSA:3.40.50.880 52 278 4.3E-67 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS31375 4f8878acdf0ab4db025d29a3a9659889 471 Pfam PF06439 Domain of Unknown Function (DUF1080) 278 456 8.3E-42 T 29-03-2018 IPR010496 Domain of unknown function DUF1080 SMALA_RS31375 4f8878acdf0ab4db025d29a3a9659889 471 Pfam PF06283 Trehalose utilisation 54 265 4.8E-87 T 29-03-2018 IPR029010 ThuA-like domain SMALA_RS29640 983c5fc9e83494eeae52752bfd772701 148 SUPERFAMILY SSF55874 36 140 2.48E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS29640 983c5fc9e83494eeae52752bfd772701 148 Gene3D G3DSA:3.30.565.10 5 148 2.6E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS29640 983c5fc9e83494eeae52752bfd772701 148 Pfam PF13581 Histidine kinase-like ATPase domain 18 137 5.9E-10 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS26435 3eeb98fd99fd49528b8e7b4cc9effd3b 814 Gene3D G3DSA:3.30.450.20 125 245 6.0E-20 T 29-03-2018 SMALA_RS26435 3eeb98fd99fd49528b8e7b4cc9effd3b 814 SUPERFAMILY SSF55785 127 240 3.66E-13 T 29-03-2018 IPR000014 PAS domain SMALA_RS26435 3eeb98fd99fd49528b8e7b4cc9effd3b 814 Pfam PF01590 GAF domain 264 426 1.8E-10 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS26435 3eeb98fd99fd49528b8e7b4cc9effd3b 814 Gene3D G3DSA:3.30.565.10 680 805 1.6E-11 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS26435 3eeb98fd99fd49528b8e7b4cc9effd3b 814 Gene3D G3DSA:3.30.450.20 8 113 2.6E-11 T 29-03-2018 SMALA_RS26435 3eeb98fd99fd49528b8e7b4cc9effd3b 814 SUPERFAMILY SSF55785 13 108 1.09E-12 T 29-03-2018 IPR000014 PAS domain SMALA_RS26435 3eeb98fd99fd49528b8e7b4cc9effd3b 814 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 484 676 5.1E-48 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS26435 3eeb98fd99fd49528b8e7b4cc9effd3b 814 SMART SM00065 247 436 9.3E-6 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS26435 3eeb98fd99fd49528b8e7b4cc9effd3b 814 SUPERFAMILY SSF81606 468 675 2.62E-6 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS26435 3eeb98fd99fd49528b8e7b4cc9effd3b 814 Pfam PF13581 Histidine kinase-like ATPase domain 689 795 3.3E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS26435 3eeb98fd99fd49528b8e7b4cc9effd3b 814 SUPERFAMILY SSF55781 325 430 1.02E-14 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS26435 3eeb98fd99fd49528b8e7b4cc9effd3b 814 Pfam PF13426 PAS domain 26 97 4.2E-5 T 29-03-2018 IPR000014 PAS domain SMALA_RS26435 3eeb98fd99fd49528b8e7b4cc9effd3b 814 Pfam PF08448 PAS fold 134 243 5.4E-18 T 29-03-2018 IPR013656 PAS fold-4 SMALA_RS26435 3eeb98fd99fd49528b8e7b4cc9effd3b 814 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 16 107 1.2E-7 T 29-03-2018 IPR000014 PAS domain SMALA_RS26435 3eeb98fd99fd49528b8e7b4cc9effd3b 814 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 132 249 3.1E-9 T 29-03-2018 IPR000014 PAS domain SMALA_RS26435 3eeb98fd99fd49528b8e7b4cc9effd3b 814 SUPERFAMILY SSF55874 719 797 5.31E-6 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS26435 3eeb98fd99fd49528b8e7b4cc9effd3b 814 Gene3D G3DSA:3.60.40.10 431 679 3.3E-41 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS26435 3eeb98fd99fd49528b8e7b4cc9effd3b 814 SMART SM00091 127 193 3.2 T 29-03-2018 IPR000014 PAS domain SMALA_RS26435 3eeb98fd99fd49528b8e7b4cc9effd3b 814 SMART SM00091 9 75 7.2E-4 T 29-03-2018 IPR000014 PAS domain SMALA_RS26435 3eeb98fd99fd49528b8e7b4cc9effd3b 814 Gene3D G3DSA:3.30.450.40 246 430 8.0E-32 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS26435 3eeb98fd99fd49528b8e7b4cc9effd3b 814 SMART SM00331 457 676 8.9E-29 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS28730 6eb74eec7a5c2d4826803454ff498a1f 225 SMART SM00448 5 119 7.4E-31 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS28730 6eb74eec7a5c2d4826803454ff498a1f 225 Pfam PF00072 Response regulator receiver domain 7 119 1.5E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS28730 6eb74eec7a5c2d4826803454ff498a1f 225 Gene3D G3DSA:3.40.50.2300 2 202 8.3E-40 T 29-03-2018 SMALA_RS28730 6eb74eec7a5c2d4826803454ff498a1f 225 SUPERFAMILY SSF52172 3 145 1.85E-37 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS09790 5a77605961f203b6114811ef74a27ca7 768 Gene3D G3DSA:3.40.50.740 338 627 2.8E-48 T 29-03-2018 SMALA_RS09790 5a77605961f203b6114811ef74a27ca7 768 PIRSF PIRSF000144 6 768 0.0 T 29-03-2018 SMALA_RS09790 5a77605961f203b6114811ef74a27ca7 768 Gene3D G3DSA:2.40.40.20 639 768 1.8E-24 T 29-03-2018 SMALA_RS09790 5a77605961f203b6114811ef74a27ca7 768 Pfam PF00384 Molybdopterin oxidoreductase 120 500 5.8E-29 T 29-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS09790 5a77605961f203b6114811ef74a27ca7 768 TIGRFAM TIGR01701 Fdhalpha-like: oxidoreductase alpha (molybdopterin) subunit 24 764 9.0E-293 T 29-03-2018 IPR010046 Oxidoreductase alpha (molybdopterin) subunit GO:0008863|GO:0030151|GO:0051539 SMALA_RS09790 5a77605961f203b6114811ef74a27ca7 768 Gene3D G3DSA:3.40.50.740 121 337 1.1E-38 T 29-03-2018 SMALA_RS09790 5a77605961f203b6114811ef74a27ca7 768 SUPERFAMILY SSF53706 58 640 2.49E-143 T 29-03-2018 SMALA_RS09790 5a77605961f203b6114811ef74a27ca7 768 Pfam PF01568 Molydopterin dinucleotide binding domain 651 758 5.8E-10 T 29-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 SMALA_RS09790 5a77605961f203b6114811ef74a27ca7 768 SUPERFAMILY SSF50692 641 765 4.75E-18 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain SMALA_RS05960 366af1b6ade40927ad139304c7f8cd01 259 Pfam PF01925 Sulfite exporter TauE/SafE 8 253 2.3E-44 T 29-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 SMALA_RS03800 4a9e51c1eeea02ec85b70f732f43c1b1 226 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 7.2E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS03800 4a9e51c1eeea02ec85b70f732f43c1b1 226 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 35 7.2E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS03800 4a9e51c1eeea02ec85b70f732f43c1b1 226 Gene3D G3DSA:1.10.260.40 44 73 5.2E-10 T 29-03-2018 SMALA_RS03800 4a9e51c1eeea02ec85b70f732f43c1b1 226 SUPERFAMILY SSF48498 87 192 1.45E-19 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS03800 4a9e51c1eeea02ec85b70f732f43c1b1 226 SUPERFAMILY SSF46689 12 83 1.99E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS03800 4a9e51c1eeea02ec85b70f732f43c1b1 226 Gene3D G3DSA:1.10.357.10 74 194 4.6E-10 T 29-03-2018 SMALA_RS03800 4a9e51c1eeea02ec85b70f732f43c1b1 226 Gene3D G3DSA:1.10.10.60 8 43 1.2E-11 T 29-03-2018 SMALA_RS03800 4a9e51c1eeea02ec85b70f732f43c1b1 226 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 67 3.0E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS32250 9e51a2f9b62db8a8b23ecc638229f328 467 Gene3D G3DSA:3.40.605.10 6 256 2.7E-95 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS32250 9e51a2f9b62db8a8b23ecc638229f328 467 Pfam PF00171 Aldehyde dehydrogenase family 14 460 3.0E-161 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS32250 9e51a2f9b62db8a8b23ecc638229f328 467 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 240 247 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 SMALA_RS32250 9e51a2f9b62db8a8b23ecc638229f328 467 SUPERFAMILY SSF53720 12 462 2.09E-154 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMALA_RS32250 9e51a2f9b62db8a8b23ecc638229f328 467 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 268 279 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 SMALA_RS32250 9e51a2f9b62db8a8b23ecc638229f328 467 Gene3D G3DSA:3.40.309.10 257 446 1.9E-65 T 29-03-2018 SMALA_RS34165 1efb5b0df4202c466f49d9e77de57528 737 Hamap MF_01961 Catalase-peroxidase [katG]. 15 737 41.759 T 29-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 SMALA_RS34165 1efb5b0df4202c466f49d9e77de57528 737 PRINTS PR00458 Haem peroxidase superfamily signature 160 177 1.3E-19 T 29-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 SMALA_RS34165 1efb5b0df4202c466f49d9e77de57528 737 PRINTS PR00458 Haem peroxidase superfamily signature 178 190 1.3E-19 T 29-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 SMALA_RS34165 1efb5b0df4202c466f49d9e77de57528 737 PRINTS PR00458 Haem peroxidase superfamily signature 264 279 1.3E-19 T 29-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 SMALA_RS34165 1efb5b0df4202c466f49d9e77de57528 737 PRINTS PR00458 Haem peroxidase superfamily signature 100 114 1.3E-19 T 29-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 SMALA_RS34165 1efb5b0df4202c466f49d9e77de57528 737 PRINTS PR00458 Haem peroxidase superfamily signature 323 338 1.3E-19 T 29-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 SMALA_RS34165 1efb5b0df4202c466f49d9e77de57528 737 Gene3D G3DSA:1.10.420.10 238 402 4.9E-41 T 29-03-2018 SMALA_RS34165 1efb5b0df4202c466f49d9e77de57528 737 Gene3D G3DSA:1.10.420.10 602 712 5.2E-36 T 29-03-2018 SMALA_RS34165 1efb5b0df4202c466f49d9e77de57528 737 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 485 511 7.5E-52 T 29-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 SMALA_RS34165 1efb5b0df4202c466f49d9e77de57528 737 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 272 295 7.5E-52 T 29-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 SMALA_RS34165 1efb5b0df4202c466f49d9e77de57528 737 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 62 75 7.5E-52 T 29-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 SMALA_RS34165 1efb5b0df4202c466f49d9e77de57528 737 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 77 102 7.5E-52 T 29-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 SMALA_RS34165 1efb5b0df4202c466f49d9e77de57528 737 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 36 58 7.5E-52 T 29-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 SMALA_RS34165 1efb5b0df4202c466f49d9e77de57528 737 Gene3D G3DSA:1.10.520.10 32 233 2.7E-55 T 29-03-2018 SMALA_RS34165 1efb5b0df4202c466f49d9e77de57528 737 TIGRFAM TIGR00198 cat_per_HPI: catalase/peroxidase HPI 32 737 0.0 T 29-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 SMALA_RS34165 1efb5b0df4202c466f49d9e77de57528 737 Gene3D G3DSA:1.10.520.10 447 601 1.8E-30 T 29-03-2018 SMALA_RS34165 1efb5b0df4202c466f49d9e77de57528 737 Pfam PF00141 Peroxidase 92 400 4.1E-50 T 29-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 SMALA_RS34165 1efb5b0df4202c466f49d9e77de57528 737 Pfam PF00141 Peroxidase 407 711 2.7E-38 T 29-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 SMALA_RS34165 1efb5b0df4202c466f49d9e77de57528 737 ProSitePatterns PS00436 Peroxidases active site signature. 100 111 - T 29-03-2018 IPR019794 Peroxidase, active site GO:0004601|GO:0055114 SMALA_RS34165 1efb5b0df4202c466f49d9e77de57528 737 SUPERFAMILY SSF48113 435 736 6.04E-110 T 29-03-2018 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 SMALA_RS34165 1efb5b0df4202c466f49d9e77de57528 737 SUPERFAMILY SSF48113 29 435 3.09E-155 T 29-03-2018 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 SMALA_RS34165 1efb5b0df4202c466f49d9e77de57528 737 ProSitePatterns PS00435 Peroxidases proximal heme-ligand signature. 264 274 - T 29-03-2018 IPR019793 Peroxidases heam-ligand binding site Reactome: R-HSA-2408557 SMALA_RS14785 751bd8e5d05239dfa00f77d5da1ef209 314 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 143 312 3.6E-28 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS14785 751bd8e5d05239dfa00f77d5da1ef209 314 SUPERFAMILY SSF161098 118 299 7.98E-30 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS14785 751bd8e5d05239dfa00f77d5da1ef209 314 Gene3D G3DSA:1.10.3720.10 64 314 5.0E-28 T 29-03-2018 SMALA_RS13395 d341c3a25a641d9c7d373d25250bd283 757 Gene3D G3DSA:3.20.20.80 199 747 4.4E-187 T 29-03-2018 SMALA_RS13395 d341c3a25a641d9c7d373d25250bd283 757 Pfam PF02446 4-alpha-glucanotransferase 208 717 1.0E-114 T 29-03-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 SMALA_RS13395 d341c3a25a641d9c7d373d25250bd283 757 SUPERFAMILY SSF51445 202 634 3.51E-138 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS13395 d341c3a25a641d9c7d373d25250bd283 757 SUPERFAMILY SSF51445 663 741 3.51E-138 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS13395 d341c3a25a641d9c7d373d25250bd283 757 TIGRFAM TIGR00217 malQ: 4-alpha-glucanotransferase 167 719 1.8E-89 T 29-03-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 SMALA_RS27565 d30e4a15715b41c538ab254c421ea4fb 346 SUPERFAMILY SSF52540 15 264 1.59E-75 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS27565 d30e4a15715b41c538ab254c421ea4fb 346 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 244 311 2.8E-18 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMALA_RS27565 d30e4a15715b41c538ab254c421ea4fb 346 SMART SM00382 50 242 4.5E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS27565 d30e4a15715b41c538ab254c421ea4fb 346 ProSitePatterns PS00211 ABC transporters family signature. 165 179 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS27565 d30e4a15715b41c538ab254c421ea4fb 346 Pfam PF00005 ABC transporter 42 192 1.5E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS27565 d30e4a15715b41c538ab254c421ea4fb 346 Gene3D G3DSA:3.40.50.300 11 344 7.0E-87 T 29-03-2018 SMALA_RS27565 d30e4a15715b41c538ab254c421ea4fb 346 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 242 330 1.5E-28 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMALA_RS08775 5eb50e5812ce28373f8218f7aaf7f8d9 354 Pfam PF01032 FecCD transport family 42 346 2.3E-82 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 SMALA_RS08775 5eb50e5812ce28373f8218f7aaf7f8d9 354 SUPERFAMILY SSF81345 26 346 9.81E-69 T 29-03-2018 IPR029022 ABC transporter, BtuC-like SMALA_RS08775 5eb50e5812ce28373f8218f7aaf7f8d9 354 Gene3D G3DSA:1.10.3470.10 26 354 1.5E-66 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SMALA_RS38240 f7ac6d8af5e4d782b76859ecd53fc3ca 3306 SUPERFAMILY SSF52777 13 194 4.89E-31 T 29-03-2018 SMALA_RS38240 f7ac6d8af5e4d782b76859ecd53fc3ca 3306 SUPERFAMILY SSF52777 2983 3248 3.0E-35 T 29-03-2018 SMALA_RS38240 f7ac6d8af5e4d782b76859ecd53fc3ca 3306 SUPERFAMILY SSF52777 2785 2993 8.12E-30 T 29-03-2018 SMALA_RS38240 f7ac6d8af5e4d782b76859ecd53fc3ca 3306 SUPERFAMILY SSF52777 1901 2151 5.23E-59 T 29-03-2018 SMALA_RS38240 f7ac6d8af5e4d782b76859ecd53fc3ca 3306 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2336 2347 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS38240 f7ac6d8af5e4d782b76859ecd53fc3ca 3306 ProSitePatterns PS00455 Putative AMP-binding domain signature. 602 613 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS38240 f7ac6d8af5e4d782b76859ecd53fc3ca 3306 Gene3D G3DSA:3.40.50.980 2180 2340 2.6E-43 T 29-03-2018 SMALA_RS38240 f7ac6d8af5e4d782b76859ecd53fc3ca 3306 SUPERFAMILY SSF56801 1525 1600 4.06E-5 T 29-03-2018 SMALA_RS38240 f7ac6d8af5e4d782b76859ecd53fc3ca 3306 Gene3D G3DSA:3.40.50.980 469 608 3.4E-42 T 29-03-2018 SMALA_RS38240 f7ac6d8af5e4d782b76859ecd53fc3ca 3306 SUPERFAMILY SSF52777 1714 1890 2.89E-43 T 29-03-2018 SMALA_RS38240 f7ac6d8af5e4d782b76859ecd53fc3ca 3306 SMART SM00823 Phosphopantetheine attachment site 1628 1697 4.0E-4 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS38240 f7ac6d8af5e4d782b76859ecd53fc3ca 3306 SMART SM00823 Phosphopantetheine attachment site 2708 2776 7.3E-11 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS38240 f7ac6d8af5e4d782b76859ecd53fc3ca 3306 SMART SM00823 Phosphopantetheine attachment site 957 1026 3.0E-4 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS38240 f7ac6d8af5e4d782b76859ecd53fc3ca 3306 Pfam PF00501 AMP-binding enzyme 2187 2596 8.5E-90 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS38240 f7ac6d8af5e4d782b76859ecd53fc3ca 3306 Pfam PF00501 AMP-binding enzyme 477 850 2.8E-84 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS38240 f7ac6d8af5e4d782b76859ecd53fc3ca 3306 Gene3D G3DSA:3.30.559.10 2 197 2.9E-22 T 29-03-2018 SMALA_RS38240 f7ac6d8af5e4d782b76859ecd53fc3ca 3306 Gene3D G3DSA:3.30.300.30 845 960 1.7E-42 T 29-03-2018 SMALA_RS38240 f7ac6d8af5e4d782b76859ecd53fc3ca 3306 Gene3D G3DSA:3.30.300.30 2592 2713 8.3E-44 T 29-03-2018 SMALA_RS38240 f7ac6d8af5e4d782b76859ecd53fc3ca 3306 Gene3D G3DSA:3.40.50.980 609 755 3.3E-21 T 29-03-2018 SMALA_RS38240 f7ac6d8af5e4d782b76859ecd53fc3ca 3306 Gene3D G3DSA:3.40.50.980 2341 2505 2.6E-28 T 29-03-2018 SMALA_RS38240 f7ac6d8af5e4d782b76859ecd53fc3ca 3306 SUPERFAMILY SSF56801 2146 2721 7.85E-150 T 29-03-2018 SMALA_RS38240 f7ac6d8af5e4d782b76859ecd53fc3ca 3306 Gene3D G3DSA:3.30.559.10 1700 1918 2.3E-43 T 29-03-2018 SMALA_RS38240 f7ac6d8af5e4d782b76859ecd53fc3ca 3306 Gene3D G3DSA:3.30.559.10 2778 3001 2.0E-25 T 29-03-2018 SMALA_RS38240 f7ac6d8af5e4d782b76859ecd53fc3ca 3306 Gene3D G3DSA:3.30.559.10 1028 1244 8.5E-48 T 29-03-2018 SMALA_RS38240 f7ac6d8af5e4d782b76859ecd53fc3ca 3306 SMART SM01294 2709 2772 0.0024 T 29-03-2018 SMALA_RS38240 f7ac6d8af5e4d782b76859ecd53fc3ca 3306 SUPERFAMILY SSF52777 1048 1220 4.78E-49 T 29-03-2018 SMALA_RS38240 f7ac6d8af5e4d782b76859ecd53fc3ca 3306 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 3114 3271 2.3E-38 T 29-03-2018 IPR010060 Non-ribosomal peptide synthase SMALA_RS38240 f7ac6d8af5e4d782b76859ecd53fc3ca 3306 Gene3D G3DSA:2.30.38.10 1523 1601 6.9E-5 T 29-03-2018 SMALA_RS38240 f7ac6d8af5e4d782b76859ecd53fc3ca 3306 SUPERFAMILY SSF52777 1231 1484 1.33E-54 T 29-03-2018 SMALA_RS38240 f7ac6d8af5e4d782b76859ecd53fc3ca 3306 Pfam PF00550 Phosphopantetheine attachment site 1631 1692 7.1E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS38240 f7ac6d8af5e4d782b76859ecd53fc3ca 3306 Pfam PF00550 Phosphopantetheine attachment site 2710 2771 1.0E-15 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS38240 f7ac6d8af5e4d782b76859ecd53fc3ca 3306 Pfam PF00550 Phosphopantetheine attachment site 960 1021 1.1E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS38240 f7ac6d8af5e4d782b76859ecd53fc3ca 3306 Pfam PF13193 AMP-binding enzyme C-terminal domain 858 931 5.0E-15 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS38240 f7ac6d8af5e4d782b76859ecd53fc3ca 3306 Pfam PF13193 AMP-binding enzyme C-terminal domain 2605 2682 1.4E-15 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS38240 f7ac6d8af5e4d782b76859ecd53fc3ca 3306 SUPERFAMILY SSF47336 950 1022 2.36E-19 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS38240 f7ac6d8af5e4d782b76859ecd53fc3ca 3306 Gene3D G3DSA:1.10.1200.10 2714 2777 2.6E-24 T 29-03-2018 SMALA_RS38240 f7ac6d8af5e4d782b76859ecd53fc3ca 3306 SUPERFAMILY SSF52777 203 441 1.67E-39 T 29-03-2018 SMALA_RS38240 f7ac6d8af5e4d782b76859ecd53fc3ca 3306 SUPERFAMILY SSF47336 2702 2772 3.53E-20 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS38240 f7ac6d8af5e4d782b76859ecd53fc3ca 3306 Pfam PF00668 Condensation domain 1045 1498 8.3E-86 T 29-03-2018 IPR001242 Condensation domain SMALA_RS38240 f7ac6d8af5e4d782b76859ecd53fc3ca 3306 Pfam PF00668 Condensation domain 2789 3258 1.9E-50 T 29-03-2018 IPR001242 Condensation domain SMALA_RS38240 f7ac6d8af5e4d782b76859ecd53fc3ca 3306 Pfam PF00668 Condensation domain 11 456 1.8E-52 T 29-03-2018 IPR001242 Condensation domain SMALA_RS38240 f7ac6d8af5e4d782b76859ecd53fc3ca 3306 Pfam PF00668 Condensation domain 1712 2167 1.7E-87 T 29-03-2018 IPR001242 Condensation domain SMALA_RS38240 f7ac6d8af5e4d782b76859ecd53fc3ca 3306 Gene3D G3DSA:1.10.1200.10 1610 1699 3.5E-22 T 29-03-2018 SMALA_RS38240 f7ac6d8af5e4d782b76859ecd53fc3ca 3306 Gene3D G3DSA:2.30.38.10 760 843 7.5E-26 T 29-03-2018 SMALA_RS38240 f7ac6d8af5e4d782b76859ecd53fc3ca 3306 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2732 2747 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS38240 f7ac6d8af5e4d782b76859ecd53fc3ca 3306 SUPERFAMILY SSF47336 1620 1725 8.64E-19 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS38240 f7ac6d8af5e4d782b76859ecd53fc3ca 3306 ProSitePatterns PS00012 Phosphopantetheine attachment site. 981 996 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS38240 f7ac6d8af5e4d782b76859ecd53fc3ca 3306 Gene3D G3DSA:1.10.1200.10 961 1027 4.2E-22 T 29-03-2018 SMALA_RS38240 f7ac6d8af5e4d782b76859ecd53fc3ca 3306 SUPERFAMILY SSF56801 436 970 7.06E-147 T 29-03-2018 SMALA_RS38240 f7ac6d8af5e4d782b76859ecd53fc3ca 3306 Gene3D G3DSA:2.30.38.10 2509 2590 9.6E-25 T 29-03-2018 SMALA_RS38240 f7ac6d8af5e4d782b76859ecd53fc3ca 3306 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2209 2621 6.8E-121 T 29-03-2018 IPR010071 Amino acid adenylation domain SMALA_RS38240 f7ac6d8af5e4d782b76859ecd53fc3ca 3306 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 498 874 3.5E-119 T 29-03-2018 IPR010071 Amino acid adenylation domain SMALA_RS42310 5896381cc5e3ed5f66ac33f2358ffb4c 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 47 70 3.3E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS42310 5896381cc5e3ed5f66ac33f2358ffb4c 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 39 3.3E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS42310 5896381cc5e3ed5f66ac33f2358ffb4c 205 SUPERFAMILY SSF46689 11 80 9.48E-20 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS42310 5896381cc5e3ed5f66ac33f2358ffb4c 205 ProSitePatterns PS01081 TetR-type HTH domain signature. 38 69 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site SMALA_RS42310 5896381cc5e3ed5f66ac33f2358ffb4c 205 Gene3D G3DSA:1.10.357.10 70 205 3.7E-14 T 29-03-2018 SMALA_RS42310 5896381cc5e3ed5f66ac33f2358ffb4c 205 Gene3D G3DSA:1.10.10.60 2 69 1.7E-21 T 29-03-2018 SMALA_RS42310 5896381cc5e3ed5f66ac33f2358ffb4c 205 SUPERFAMILY SSF48498 93 198 2.45E-5 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS42310 5896381cc5e3ed5f66ac33f2358ffb4c 205 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 72 1.2E-15 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS26440 5f5dd93e925a6d7fdc65bdfafdfdf046 311 Gene3D G3DSA:3.40.50.720 11 259 5.8E-30 T 29-03-2018 SMALA_RS26440 5f5dd93e925a6d7fdc65bdfafdfdf046 311 SUPERFAMILY SSF51735 14 270 7.86E-59 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS26440 5f5dd93e925a6d7fdc65bdfafdfdf046 311 Pfam PF05368 NmrA-like family 14 247 1.1E-42 T 29-03-2018 IPR008030 NmrA-like domain Reactome: R-HSA-70635 SMALA_RS29535 76b145899bd88781edfefbe542eed5fa 651 SUPERFAMILY SSF56112 186 248 3.04E-25 T 29-03-2018 IPR011009 Protein kinase-like domain SMALA_RS29535 76b145899bd88781edfefbe542eed5fa 651 SUPERFAMILY SSF56112 290 435 3.04E-25 T 29-03-2018 IPR011009 Protein kinase-like domain SMALA_RS29535 76b145899bd88781edfefbe542eed5fa 651 Pfam PF03109 ABC1 family 203 324 1.2E-29 T 29-03-2018 IPR004147 UbiB domain SMALA_RS29535 76b145899bd88781edfefbe542eed5fa 651 Gene3D G3DSA:1.10.510.10 346 460 3.1E-4 T 29-03-2018 SMALA_RS29535 76b145899bd88781edfefbe542eed5fa 651 Gene3D G3DSA:3.30.200.20 193 337 2.6E-25 T 29-03-2018 SMALA_RS05990 6f7579af85b4794ae47b4465760cba7d 463 PRINTS PR00344 Bacterial sensor protein C-terminal signature 391 405 2.5E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS05990 6f7579af85b4794ae47b4465760cba7d 463 PRINTS PR00344 Bacterial sensor protein C-terminal signature 409 419 2.5E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS05990 6f7579af85b4794ae47b4465760cba7d 463 PRINTS PR00344 Bacterial sensor protein C-terminal signature 424 442 2.5E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS05990 6f7579af85b4794ae47b4465760cba7d 463 PRINTS PR00344 Bacterial sensor protein C-terminal signature 448 461 2.5E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS05990 6f7579af85b4794ae47b4465760cba7d 463 SUPERFAMILY SSF47384 230 310 6.47E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS05990 6f7579af85b4794ae47b4465760cba7d 463 Gene3D G3DSA:3.30.565.10 319 463 1.1E-25 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS05990 6f7579af85b4794ae47b4465760cba7d 463 SMART SM00388 247 313 1.3E-8 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS05990 6f7579af85b4794ae47b4465760cba7d 463 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 361 462 1.6E-13 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS05990 6f7579af85b4794ae47b4465760cba7d 463 SUPERFAMILY SSF55874 351 462 3.01E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS05990 6f7579af85b4794ae47b4465760cba7d 463 SMART SM00387 356 463 2.3E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS05990 6f7579af85b4794ae47b4465760cba7d 463 Pfam PF00512 His Kinase A (phospho-acceptor) domain 250 311 7.8E-9 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS05990 6f7579af85b4794ae47b4465760cba7d 463 Gene3D G3DSA:1.10.287.130 237 309 1.2E-9 T 29-03-2018 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 ProSitePatterns PS00012 Phosphopantetheine attachment site. 5098 5113 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 3917 4032 7.7E-43 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 287 402 5.5E-43 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 5416 5531 5.7E-42 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 7368 7483 6.5E-42 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2213 2328 8.2E-42 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 5534 5653 8.1E-14 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 405 524 2.3E-14 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2331 2447 4.8E-15 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 7486 7602 3.1E-17 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 4035 4153 3.6E-14 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 SUPERFAMILY SSF52151 5854 5942 9.94E-60 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 SUPERFAMILY SSF52151 5669 5795 9.94E-60 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 SUPERFAMILY SSF53901 7111 7480 1.29E-99 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 SUPERFAMILY SSF50129 1305 1430 2.52E-26 T 29-03-2018 IPR011032 GroES-like SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 SUPERFAMILY SSF50129 6435 6560 1.42E-26 T 29-03-2018 IPR011032 GroES-like SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 SUPERFAMILY SSF47336 5066 5178 6.41E-23 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 Gene3D G3DSA:3.40.366.10 4329 4443 1.5E-13 T 29-03-2018 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 Gene3D G3DSA:3.40.366.10 2663 2780 8.7E-24 T 29-03-2018 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 SUPERFAMILY SSF51735 3129 3278 5.9E-23 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 Gene3D G3DSA:3.10.129.10 2844 2965 7.4E-5 T 29-03-2018 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 Gene3D G3DSA:3.10.129.10 883 1003 5.0E-5 T 29-03-2018 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 Gene3D G3DSA:3.10.129.10 6012 6137 2.7E-6 T 29-03-2018 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 2118 2134 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 SMART SM01294 7015 7078 2.6E-4 T 29-03-2018 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 SMART SM01294 1869 1936 3.2E-5 T 29-03-2018 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 SMART SM01294 3573 3640 7.7E-5 T 29-03-2018 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 SMART SM00826 6012 6170 6.4E-73 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 SMART SM00826 4486 4617 1.1E-10 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 SMART SM00826 2844 3007 9.3E-73 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 SMART SM00826 883 1041 2.2E-71 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 3822 3838 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 Gene3D G3DSA:1.10.1200.10 3564 3662 1.4E-18 T 29-03-2018 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 Gene3D G3DSA:1.10.1200.10 1860 1958 8.8E-20 T 29-03-2018 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 Gene3D G3DSA:1.10.1200.10 5063 5161 2.9E-18 T 29-03-2018 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 Gene3D G3DSA:1.10.1200.10 7006 7110 3.0E-18 T 29-03-2018 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 Gene3D G3DSA:3.40.366.10 7631 7777 2.4E-40 T 29-03-2018 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 Gene3D G3DSA:3.40.366.10 2477 2623 3.0E-45 T 29-03-2018 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 Gene3D G3DSA:3.40.366.10 703 819 7.7E-21 T 29-03-2018 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 SUPERFAMILY SSF52151 540 666 2.07E-59 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 SUPERFAMILY SSF52151 725 813 2.07E-59 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 SUPERFAMILY SSF47336 7004 7084 3.27E-20 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 SUPERFAMILY SSF55048 5794 5853 4.45E-7 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 SUPERFAMILY SSF51735 4812 5043 2.28E-42 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 7638 7935 1.2E-103 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 4173 4439 2.4E-90 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 5673 5953 2.0E-90 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2484 2777 6.3E-115 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 544 824 2.7E-90 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 SUPERFAMILY SSF51735 6218 6406 4.13E-14 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 SUPERFAMILY SSF47336 8012 8094 5.63E-17 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 SUPERFAMILY SSF53901 1956 2319 1.44E-100 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 SUPERFAMILY SSF47336 3567 3678 1.57E-22 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 SMART SM00823 Phosphopantetheine attachment site 1868 1940 1.9E-27 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 SMART SM00823 Phosphopantetheine attachment site 7010 7082 2.6E-27 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 SMART SM00823 Phosphopantetheine attachment site 5071 5143 7.8E-26 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 SMART SM00823 Phosphopantetheine attachment site 8015 8087 8.5E-23 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 SMART SM00823 Phosphopantetheine attachment site 3572 3644 4.9E-29 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 SUPERFAMILY SSF47336 1863 1975 1.19E-23 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 ProSitePatterns PS00012 Phosphopantetheine attachment site. 7037 7052 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 Pfam PF00550 Phosphopantetheine attachment site 1871 1936 1.6E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 Pfam PF00550 Phosphopantetheine attachment site 5074 5138 4.2E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 Pfam PF00550 Phosphopantetheine attachment site 7013 7077 4.6E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 Pfam PF00550 Phosphopantetheine attachment site 3575 3639 2.7E-9 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 Pfam PF00550 Phosphopantetheine attachment site 8032 8083 8.6E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 SUPERFAMILY SSF52151 4341 4421 3.92E-57 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 SUPERFAMILY SSF52151 4169 4284 3.92E-57 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 SUPERFAMILY SSF51735 6526 6661 1.25E-35 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 SUPERFAMILY SSF51735 1606 1806 5.59E-38 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 SUPERFAMILY SSF51735 6736 6967 2.26E-38 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 SMART SM00829 1298 1599 7.2E-173 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 SMART SM00829 6428 6729 3.5E-174 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 Gene3D G3DSA:3.30.70.250 2624 2662 7.3E-12 T 29-03-2018 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 Gene3D G3DSA:3.30.70.250 7778 7818 4.3E-17 T 29-03-2018 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 SUPERFAMILY SSF51735 1396 1532 1.25E-34 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 5163 5408 9.0E-85 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 7113 7360 4.3E-85 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1960 2205 3.3E-84 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3664 3909 8.0E-85 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 279 1.3E-85 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 SUPERFAMILY SSF55048 2608 2669 3.92E-9 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 5321 5337 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6739 6911 4.7E-47 T 29-03-2018 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1609 1781 6.9E-49 T 29-03-2018 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4816 4988 6.4E-54 T 29-03-2018 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3292 3470 3.0E-46 T 29-03-2018 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 Pfam PF14765 Polyketide synthase dehydratase 2844 3123 1.0E-47 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 Pfam PF14765 Polyketide synthase dehydratase 6012 6275 1.1E-53 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 Pfam PF14765 Polyketide synthase dehydratase 883 1146 9.0E-53 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 Gene3D G3DSA:3.90.180.10 6418 6731 5.5E-60 T 29-03-2018 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 Gene3D G3DSA:3.90.180.10 1273 1601 9.8E-61 T 29-03-2018 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 SUPERFAMILY SSF52151 7829 7923 2.33E-64 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 SUPERFAMILY SSF52151 7634 7766 2.33E-64 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 SUPERFAMILY SSF55048 665 724 8.24E-8 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 SUPERFAMILY SSF53901 3660 4029 3.25E-101 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 Pfam PF13602 Zinc-binding dehydrogenase 1471 1599 2.6E-19 T 29-03-2018 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 Pfam PF13602 Zinc-binding dehydrogenase 6602 6729 1.2E-18 T 29-03-2018 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 ProSitePatterns PS00012 Phosphopantetheine attachment site. 8042 8057 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 Gene3D G3DSA:3.40.47.10 26 291 2.1E-81 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 Gene3D G3DSA:3.40.47.10 1959 2217 2.7E-80 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 Gene3D G3DSA:3.40.47.10 5162 5420 7.3E-79 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 Gene3D G3DSA:3.40.47.10 7111 7372 3.6E-77 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 Gene3D G3DSA:3.40.47.10 3663 3921 7.0E-80 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 Gene3D G3DSA:3.40.47.10 7373 7534 2.3E-60 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 Pfam PF08659 KR domain 4816 4987 7.9E-57 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 Pfam PF08659 KR domain 3293 3468 3.6E-44 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 Pfam PF08659 KR domain 6739 6910 9.6E-53 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 Pfam PF08659 KR domain 1609 1780 1.0E-53 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 Gene3D G3DSA:1.10.1200.10 7994 8094 3.8E-16 T 29-03-2018 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 SUPERFAMILY SSF53901 5159 5522 3.85E-100 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 Gene3D G3DSA:3.40.366.10 4163 4328 1.0E-47 T 29-03-2018 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 Gene3D G3DSA:3.40.366.10 534 702 2.4E-46 T 29-03-2018 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 Pfam PF00698 Acyl transferase domain 7637 7919 1.9E-51 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 Pfam PF00698 Acyl transferase domain 4171 4416 1.4E-40 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 Pfam PF00698 Acyl transferase domain 5671 5971 1.5E-66 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 Pfam PF00698 Acyl transferase domain 542 842 6.7E-66 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 Pfam PF00698 Acyl transferase domain 2483 2795 6.3E-84 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 Pfam PF08990 Erythronolide synthase docking 3 26 3.2E-8 T 29-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 SUPERFAMILY SSF51735 3291 3513 3.94E-40 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 SUPERFAMILY SSF55048 7764 7827 7.32E-10 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 SUPERFAMILY SSF55048 4283 4332 1.27E-7 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 SUPERFAMILY SSF51735 4633 4798 5.9E-13 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3599 3614 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 Gene3D G3DSA:3.40.50.720 4810 5038 1.1E-45 T 29-03-2018 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 Gene3D G3DSA:3.40.50.720 1602 1829 1.4E-41 T 29-03-2018 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 Gene3D G3DSA:3.40.50.720 3284 3541 3.0E-42 T 29-03-2018 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 Gene3D G3DSA:3.40.50.720 6732 6959 5.3E-42 T 29-03-2018 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 Gene3D G3DSA:3.40.47.10 294 453 1.4E-61 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 Gene3D G3DSA:3.40.47.10 3924 4083 1.9E-60 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 Gene3D G3DSA:3.40.47.10 2220 2379 3.5E-61 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 Gene3D G3DSA:3.40.47.10 5423 5582 2.1E-61 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 SUPERFAMILY SSF51735 1087 1277 6.69E-14 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 SUPERFAMILY SSF53901 32 399 7.07E-102 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 SUPERFAMILY SSF52151 2670 2773 3.4E-68 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 SUPERFAMILY SSF52151 2481 2609 3.4E-68 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 SMART SM00825 Beta-ketoacyl synthase 5165 5584 7.3E-209 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 SMART SM00825 Beta-ketoacyl synthase 7115 7536 4.4E-199 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 SMART SM00825 Beta-ketoacyl synthase 36 455 1.3E-208 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 SMART SM00825 Beta-ketoacyl synthase 1962 2381 1.1E-210 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 SMART SM00825 Beta-ketoacyl synthase 3666 4085 4.2E-209 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 Gene3D G3DSA:3.40.366.10 7819 7934 5.3E-30 T 29-03-2018 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 Gene3D G3DSA:3.40.366.10 5659 5959 6.8E-69 T 29-03-2018 SMALA_RS42010 6014893ec25d682088b5ad52be6cde3a 8134 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1895 1910 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS19910 1df0a8e4ad127cf262b73ab8b1666684 369 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 285 358 4.9E-14 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SMALA_RS19910 1df0a8e4ad127cf262b73ab8b1666684 369 PRINTS PR00406 Cytochrome B5 reductase signature 107 121 5.4E-6 T 29-03-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 SMALA_RS19910 1df0a8e4ad127cf262b73ab8b1666684 369 PRINTS PR00406 Cytochrome B5 reductase signature 129 148 5.4E-6 T 29-03-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 SMALA_RS19910 1df0a8e4ad127cf262b73ab8b1666684 369 PRINTS PR00406 Cytochrome B5 reductase signature 46 57 5.4E-6 T 29-03-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 SMALA_RS19910 1df0a8e4ad127cf262b73ab8b1666684 369 Pfam PF00175 Oxidoreductase NAD-binding domain 132 239 8.9E-8 T 29-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 SMALA_RS19910 1df0a8e4ad127cf262b73ab8b1666684 369 Gene3D G3DSA:3.40.50.80 111 250 2.5E-24 T 29-03-2018 SMALA_RS19910 1df0a8e4ad127cf262b73ab8b1666684 369 SUPERFAMILY SSF54292 250 363 3.93E-26 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SMALA_RS19910 1df0a8e4ad127cf262b73ab8b1666684 369 Gene3D G3DSA:3.10.20.30 251 369 3.9E-29 T 29-03-2018 IPR012675 Beta-grasp domain SMALA_RS19910 1df0a8e4ad127cf262b73ab8b1666684 369 SUPERFAMILY SSF52343 110 255 5.5E-29 T 29-03-2018 SMALA_RS19910 1df0a8e4ad127cf262b73ab8b1666684 369 Gene3D G3DSA:2.40.30.10 9 110 3.2E-17 T 29-03-2018 SMALA_RS19910 1df0a8e4ad127cf262b73ab8b1666684 369 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 316 324 - T 29-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 SMALA_RS19910 1df0a8e4ad127cf262b73ab8b1666684 369 Pfam PF00970 Oxidoreductase FAD-binding domain 20 119 1.4E-9 T 29-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 SMALA_RS19910 1df0a8e4ad127cf262b73ab8b1666684 369 SUPERFAMILY SSF63380 15 123 5.55E-21 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 SMALA_RS31690 abc5a4db06d9d0b39a7af8a0eccdf41b 487 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 317 343 2.4E-39 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 SMALA_RS31690 abc5a4db06d9d0b39a7af8a0eccdf41b 487 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 146 159 2.4E-39 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 SMALA_RS31690 abc5a4db06d9d0b39a7af8a0eccdf41b 487 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 240 256 2.4E-39 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 SMALA_RS31690 abc5a4db06d9d0b39a7af8a0eccdf41b 487 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 222 239 2.4E-39 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 SMALA_RS31690 abc5a4db06d9d0b39a7af8a0eccdf41b 487 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 170 198 2.4E-39 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 SMALA_RS31690 abc5a4db06d9d0b39a7af8a0eccdf41b 487 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 9 477 75.303 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 SMALA_RS31690 abc5a4db06d9d0b39a7af8a0eccdf41b 487 Gene3D G3DSA:3.30.360.10 193 482 3.7E-97 T 29-03-2018 SMALA_RS31690 abc5a4db06d9d0b39a7af8a0eccdf41b 487 SUPERFAMILY SSF51735 7 193 1.26E-46 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS31690 abc5a4db06d9d0b39a7af8a0eccdf41b 487 SUPERFAMILY SSF55347 180 474 2.32E-93 T 29-03-2018 SMALA_RS31690 abc5a4db06d9d0b39a7af8a0eccdf41b 487 ProSitePatterns PS00069 Glucose-6-phosphate dehydrogenase active site. 180 186 - T 29-03-2018 IPR019796 Glucose-6-phosphate dehydrogenase, active site GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 SMALA_RS31690 abc5a4db06d9d0b39a7af8a0eccdf41b 487 PIRSF PIRSF000110 4 475 1.8E-137 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 SMALA_RS31690 abc5a4db06d9d0b39a7af8a0eccdf41b 487 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 13 190 5.1E-46 T 29-03-2018 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 SMALA_RS31690 abc5a4db06d9d0b39a7af8a0eccdf41b 487 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 192 463 2.5E-85 T 29-03-2018 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 SMALA_RS31690 abc5a4db06d9d0b39a7af8a0eccdf41b 487 Gene3D G3DSA:3.40.50.720 7 192 3.6E-57 T 29-03-2018 SMALA_RS31690 abc5a4db06d9d0b39a7af8a0eccdf41b 487 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 9 468 8.6E-139 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 SMALA_RS20020 2357497b98e3c850c9ad9378930f7ff4 529 SMART SM00220 38 300 1.5E-58 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMALA_RS20020 2357497b98e3c850c9ad9378930f7ff4 529 SUPERFAMILY SSF56112 36 297 9.71E-73 T 29-03-2018 IPR011009 Protein kinase-like domain SMALA_RS20020 2357497b98e3c850c9ad9378930f7ff4 529 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 161 173 - T 29-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMALA_RS20020 2357497b98e3c850c9ad9378930f7ff4 529 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 44 67 - T 29-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 SMALA_RS20020 2357497b98e3c850c9ad9378930f7ff4 529 Pfam PF00069 Protein kinase domain 38 293 5.8E-47 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMALA_RS20020 2357497b98e3c850c9ad9378930f7ff4 529 Gene3D G3DSA:1.10.510.10 125 449 2.5E-51 T 29-03-2018 SMALA_RS20020 2357497b98e3c850c9ad9378930f7ff4 529 Gene3D G3DSA:3.30.200.20 33 124 3.4E-18 T 29-03-2018 SMALA_RS05560 9c3af79fe3ea4a1c2258b14aae7b388e 218 Gene3D G3DSA:1.10.10.60 1 63 6.9E-18 T 29-03-2018 SMALA_RS05560 9c3af79fe3ea4a1c2258b14aae7b388e 218 Gene3D G3DSA:1.10.357.10 64 195 6.0E-21 T 29-03-2018 SMALA_RS05560 9c3af79fe3ea4a1c2258b14aae7b388e 218 SUPERFAMILY SSF48498 109 177 2.42E-10 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS05560 9c3af79fe3ea4a1c2258b14aae7b388e 218 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 2.4E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS05560 9c3af79fe3ea4a1c2258b14aae7b388e 218 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 2.4E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS05560 9c3af79fe3ea4a1c2258b14aae7b388e 218 SUPERFAMILY SSF46689 15 80 1.54E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS05560 9c3af79fe3ea4a1c2258b14aae7b388e 218 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 65 1.9E-16 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS13760 e899bcdea842c9153087a43080fc5ad3 3902 Pfam PF14765 Polyketide synthase dehydratase 953 1228 2.2E-59 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13760 e899bcdea842c9153087a43080fc5ad3 3902 Pfam PF14765 Polyketide synthase dehydratase 2739 3023 2.6E-54 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13760 e899bcdea842c9153087a43080fc5ad3 3902 SUPERFAMILY SSF101173 1 33 3.92E-5 T 29-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 SMALA_RS13760 e899bcdea842c9153087a43080fc5ad3 3902 SMART SM00823 Phosphopantetheine attachment site 3536 3608 1.2E-26 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13760 e899bcdea842c9153087a43080fc5ad3 3902 SMART SM00823 Phosphopantetheine attachment site 1751 1823 2.6E-33 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13760 e899bcdea842c9153087a43080fc5ad3 3902 Gene3D G3DSA:3.40.50.1820 3638 3902 2.4E-26 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS13760 e899bcdea842c9153087a43080fc5ad3 3902 SUPERFAMILY SSF55048 2497 2563 6.02E-14 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS13760 e899bcdea842c9153087a43080fc5ad3 3902 SUPERFAMILY SSF51735 3245 3462 1.12E-43 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS13760 e899bcdea842c9153087a43080fc5ad3 3902 Gene3D G3DSA:3.10.129.10 955 1079 3.0E-6 T 29-03-2018 SMALA_RS13760 e899bcdea842c9153087a43080fc5ad3 3902 Gene3D G3DSA:3.10.129.10 2745 2858 5.8E-6 T 29-03-2018 SMALA_RS13760 e899bcdea842c9153087a43080fc5ad3 3902 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3247 3427 3.7E-61 T 29-03-2018 SMALA_RS13760 e899bcdea842c9153087a43080fc5ad3 3902 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1465 1645 4.2E-61 T 29-03-2018 SMALA_RS13760 e899bcdea842c9153087a43080fc5ad3 3902 SUPERFAMILY SSF52151 2564 2660 4.19E-65 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS13760 e899bcdea842c9153087a43080fc5ad3 3902 SUPERFAMILY SSF52151 2369 2498 4.19E-65 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS13760 e899bcdea842c9153087a43080fc5ad3 3902 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 33 283 1.5E-90 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS13760 e899bcdea842c9153087a43080fc5ad3 3902 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1843 2093 3.4E-93 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS13760 e899bcdea842c9153087a43080fc5ad3 3902 Pfam PF00975 Thioesterase domain 3698 3900 5.2E-20 T 29-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 SMALA_RS13760 e899bcdea842c9153087a43080fc5ad3 3902 Gene3D G3DSA:3.40.366.10 768 882 1.5E-25 T 29-03-2018 SMALA_RS13760 e899bcdea842c9153087a43080fc5ad3 3902 SUPERFAMILY SSF47336 1750 1858 3.66E-25 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS13760 e899bcdea842c9153087a43080fc5ad3 3902 Gene3D G3DSA:3.40.47.10 2108 2269 3.6E-62 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13760 e899bcdea842c9153087a43080fc5ad3 3902 Gene3D G3DSA:3.40.47.10 298 459 7.3E-62 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13760 e899bcdea842c9153087a43080fc5ad3 3902 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 2006 2022 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS13760 e899bcdea842c9153087a43080fc5ad3 3902 SMART SM00825 Beta-ketoacyl synthase 1845 2271 6.7E-227 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS13760 e899bcdea842c9153087a43080fc5ad3 3902 SMART SM00825 Beta-ketoacyl synthase 35 461 9.3E-229 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS13760 e899bcdea842c9153087a43080fc5ad3 3902 SUPERFAMILY SSF51735 1462 1673 3.71E-46 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS13760 e899bcdea842c9153087a43080fc5ad3 3902 Gene3D G3DSA:2.60.120.260 1163 1243 0.54 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS13760 e899bcdea842c9153087a43080fc5ad3 3902 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 411 555 1.2E-12 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13760 e899bcdea842c9153087a43080fc5ad3 3902 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2221 2335 2.9E-15 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13760 e899bcdea842c9153087a43080fc5ad3 3902 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 196 212 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS13760 e899bcdea842c9153087a43080fc5ad3 3902 Gene3D G3DSA:1.10.1200.10 3529 3637 1.7E-18 T 29-03-2018 SMALA_RS13760 e899bcdea842c9153087a43080fc5ad3 3902 Gene3D G3DSA:1.10.1200.10 1747 1844 8.1E-22 T 29-03-2018 SMALA_RS13760 e899bcdea842c9153087a43080fc5ad3 3902 Gene3D G3DSA:3.40.366.10 2557 2678 1.8E-24 T 29-03-2018 SMALA_RS13760 e899bcdea842c9153087a43080fc5ad3 3902 SMART SM00826 953 1116 1.8E-89 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13760 e899bcdea842c9153087a43080fc5ad3 3902 SMART SM00826 2739 2909 1.0E-89 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13760 e899bcdea842c9153087a43080fc5ad3 3902 SUPERFAMILY SSF51735 1235 1451 4.33E-24 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS13760 e899bcdea842c9153087a43080fc5ad3 3902 SMART SM00824 Thioesterase 3691 3901 7.7E-124 T 29-03-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 SMALA_RS13760 e899bcdea842c9153087a43080fc5ad3 3902 SUPERFAMILY SSF51735 3029 3228 3.66E-39 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS13760 e899bcdea842c9153087a43080fc5ad3 3902 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 291 408 2.8E-42 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS13760 e899bcdea842c9153087a43080fc5ad3 3902 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2101 2218 3.5E-43 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS13760 e899bcdea842c9153087a43080fc5ad3 3902 Pfam PF08990 Erythronolide synthase docking 2 26 2.3E-11 T 29-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 SMALA_RS13760 e899bcdea842c9153087a43080fc5ad3 3902 Gene3D G3DSA:3.40.366.10 585 729 3.6E-53 T 29-03-2018 SMALA_RS13760 e899bcdea842c9153087a43080fc5ad3 3902 Gene3D G3DSA:3.40.366.10 2366 2509 2.8E-44 T 29-03-2018 SMALA_RS13760 e899bcdea842c9153087a43080fc5ad3 3902 SUPERFAMILY SSF52151 769 871 9.42E-76 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS13760 e899bcdea842c9153087a43080fc5ad3 3902 SUPERFAMILY SSF52151 589 710 9.42E-76 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS13760 e899bcdea842c9153087a43080fc5ad3 3902 SUPERFAMILY SSF53474 3566 3604 1.99E-38 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS13760 e899bcdea842c9153087a43080fc5ad3 3902 SUPERFAMILY SSF53474 3666 3901 1.99E-38 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS13760 e899bcdea842c9153087a43080fc5ad3 3902 SMART SM01294 1752 1819 1.4E-6 T 29-03-2018 SMALA_RS13760 e899bcdea842c9153087a43080fc5ad3 3902 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2373 2672 8.4E-121 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS13760 e899bcdea842c9153087a43080fc5ad3 3902 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 592 886 6.9E-127 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS13760 e899bcdea842c9153087a43080fc5ad3 3902 Pfam PF00550 Phosphopantetheine attachment site 3539 3598 5.4E-9 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS13760 e899bcdea842c9153087a43080fc5ad3 3902 Pfam PF00550 Phosphopantetheine attachment site 1754 1819 8.8E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS13760 e899bcdea842c9153087a43080fc5ad3 3902 Gene3D G3DSA:3.40.50.720 3240 3502 3.4E-47 T 29-03-2018 SMALA_RS13760 e899bcdea842c9153087a43080fc5ad3 3902 Gene3D G3DSA:3.40.50.720 1457 1717 2.4E-47 T 29-03-2018 SMALA_RS13760 e899bcdea842c9153087a43080fc5ad3 3902 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1778 1793 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS13760 e899bcdea842c9153087a43080fc5ad3 3902 Pfam PF08659 KR domain 1465 1644 3.0E-60 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13760 e899bcdea842c9153087a43080fc5ad3 3902 Pfam PF08659 KR domain 3247 3425 4.0E-58 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13760 e899bcdea842c9153087a43080fc5ad3 3902 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 1288 1307 - T 29-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 SMALA_RS13760 e899bcdea842c9153087a43080fc5ad3 3902 SUPERFAMILY SSF53901 1839 2216 2.18E-103 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13760 e899bcdea842c9153087a43080fc5ad3 3902 SUPERFAMILY SSF55048 714 776 3.27E-12 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS13760 e899bcdea842c9153087a43080fc5ad3 3902 Pfam PF00698 Acyl transferase domain 591 905 5.1E-58 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS13760 e899bcdea842c9153087a43080fc5ad3 3902 Pfam PF00698 Acyl transferase domain 2372 2690 1.0E-87 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS13760 e899bcdea842c9153087a43080fc5ad3 3902 Gene3D G3DSA:3.30.70.250 2510 2556 2.1E-19 T 29-03-2018 SMALA_RS13760 e899bcdea842c9153087a43080fc5ad3 3902 Gene3D G3DSA:3.30.70.250 730 767 3.3E-19 T 29-03-2018 SMALA_RS13760 e899bcdea842c9153087a43080fc5ad3 3902 Gene3D G3DSA:3.40.47.10 1845 2105 7.8E-86 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13760 e899bcdea842c9153087a43080fc5ad3 3902 Gene3D G3DSA:3.40.47.10 25 295 4.2E-88 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13760 e899bcdea842c9153087a43080fc5ad3 3902 SUPERFAMILY SSF53901 30 405 4.99E-102 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS17995 d05cf469bb46509231bf51248e84114a 346 Gene3D G3DSA:3.20.20.70 201 330 2.6E-43 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS17995 d05cf469bb46509231bf51248e84114a 346 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 86 173 1.3E-22 T 29-03-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 SMALA_RS17995 d05cf469bb46509231bf51248e84114a 346 SUPERFAMILY SSF51690 175 340 5.49E-57 T 29-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 SMALA_RS17995 d05cf469bb46509231bf51248e84114a 346 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 175 339 1.7E-57 T 29-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 SMALA_RS17995 d05cf469bb46509231bf51248e84114a 346 Gene3D G3DSA:3.90.1170.20 55 200 4.6E-41 T 29-03-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 SMALA_RS17995 d05cf469bb46509231bf51248e84114a 346 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 77 339 1.1E-91 T 29-03-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 SMALA_RS17995 d05cf469bb46509231bf51248e84114a 346 SUPERFAMILY SSF54675 67 174 7.85E-26 T 29-03-2018 SMALA_RS32940 ac3bf21643c020c8758aa422ec2460fb 176 Gene3D G3DSA:3.40.50.2020 2 175 3.0E-39 T 29-03-2018 SMALA_RS32940 ac3bf21643c020c8758aa422ec2460fb 176 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 5 176 35.421 T 29-03-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 SMALA_RS32940 ac3bf21643c020c8758aa422ec2460fb 176 TIGRFAM TIGR01090 apt: adenine phosphoribosyltransferase 6 166 8.3E-59 T 29-03-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 SMALA_RS32940 ac3bf21643c020c8758aa422ec2460fb 176 SUPERFAMILY SSF53271 8 164 2.36E-47 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like SMALA_RS32940 ac3bf21643c020c8758aa422ec2460fb 176 Pfam PF00156 Phosphoribosyl transferase domain 42 150 2.8E-14 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 SMALA_RS36980 515f1e988c985c2f04d7df7e8ed29274 461 SUPERFAMILY SSF103473 16 456 1.24E-85 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS36980 515f1e988c985c2f04d7df7e8ed29274 461 PIRSF PIRSF002808 29 387 2.2E-33 T 29-03-2018 IPR000849 Sugar phosphate transporter GO:0005215|GO:0006810|GO:0016021 SMALA_RS36980 515f1e988c985c2f04d7df7e8ed29274 461 PIRSF PIRSF002808 390 459 0.3 T 29-03-2018 IPR000849 Sugar phosphate transporter GO:0005215|GO:0006810|GO:0016021 SMALA_RS36980 515f1e988c985c2f04d7df7e8ed29274 461 Pfam PF07690 Major Facilitator Superfamily 41 413 4.7E-62 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS36980 515f1e988c985c2f04d7df7e8ed29274 461 Gene3D G3DSA:1.20.1250.20 26 226 6.1E-40 T 29-03-2018 SMALA_RS36980 515f1e988c985c2f04d7df7e8ed29274 461 Gene3D G3DSA:1.20.1250.20 250 460 8.1E-25 T 29-03-2018 SMALA_RS12380 b5ce2e6c736e9521381cfa6bbb743b0d 770 SUPERFAMILY SSF50692 617 766 9.04E-46 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain SMALA_RS12380 b5ce2e6c736e9521381cfa6bbb743b0d 770 Gene3D G3DSA:3.40.50.740 73 179 1.5E-25 T 29-03-2018 SMALA_RS12380 b5ce2e6c736e9521381cfa6bbb743b0d 770 SUPERFAMILY SSF53706 627 660 2.36E-158 T 29-03-2018 SMALA_RS12380 b5ce2e6c736e9521381cfa6bbb743b0d 770 SUPERFAMILY SSF53706 15 559 2.36E-158 T 29-03-2018 SMALA_RS12380 b5ce2e6c736e9521381cfa6bbb743b0d 770 SMART SM00926 12 70 4.7E-8 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS12380 b5ce2e6c736e9521381cfa6bbb743b0d 770 Gene3D G3DSA:2.20.25.90 7 71 4.4E-16 T 29-03-2018 SMALA_RS12380 b5ce2e6c736e9521381cfa6bbb743b0d 770 Gene3D G3DSA:3.40.228.10 180 270 1.8E-25 T 29-03-2018 SMALA_RS12380 b5ce2e6c736e9521381cfa6bbb743b0d 770 Pfam PF01568 Molydopterin dinucleotide binding domain 656 762 2.3E-30 T 29-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 SMALA_RS12380 b5ce2e6c736e9521381cfa6bbb743b0d 770 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 15 66 2.8E-10 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS12380 b5ce2e6c736e9521381cfa6bbb743b0d 770 Gene3D G3DSA:2.40.40.20 616 767 5.0E-42 T 29-03-2018 SMALA_RS12380 b5ce2e6c736e9521381cfa6bbb743b0d 770 Gene3D G3DSA:3.40.50.740 271 556 1.2E-68 T 29-03-2018 SMALA_RS12380 b5ce2e6c736e9521381cfa6bbb743b0d 770 Pfam PF00384 Molybdopterin oxidoreductase 73 499 3.8E-70 T 29-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS28800 11acb18118526771f953d7ad424e3de3 335 Gene3D G3DSA:1.50.10.20 61 250 6.3E-9 T 29-03-2018 SMALA_RS28800 11acb18118526771f953d7ad424e3de3 335 Gene3D G3DSA:1.50.10.20 265 334 3.0E-5 T 29-03-2018 SMALA_RS28800 11acb18118526771f953d7ad424e3de3 335 SUPERFAMILY SSF48239 281 333 1.36E-8 T 29-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid SMALA_RS28800 11acb18118526771f953d7ad424e3de3 335 SUPERFAMILY SSF48239 68 199 1.36E-8 T 29-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid SMALA_RS12880 e7e9551a2bf3c075a719d67edda2b566 348 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 158 174 4.8E-29 T 29-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 SMALA_RS12880 e7e9551a2bf3c075a719d67edda2b566 348 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 179 190 4.8E-29 T 29-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 SMALA_RS12880 e7e9551a2bf3c075a719d67edda2b566 348 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 122 142 4.8E-29 T 29-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 SMALA_RS12880 e7e9551a2bf3c075a719d67edda2b566 348 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 260 276 4.8E-29 T 29-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 SMALA_RS12880 e7e9551a2bf3c075a719d67edda2b566 348 SUPERFAMILY SSF55486 54 338 1.54E-80 T 29-03-2018 SMALA_RS12880 e7e9551a2bf3c075a719d67edda2b566 348 Gene3D G3DSA:3.10.170.10 1 171 1.4E-56 T 29-03-2018 SMALA_RS12880 e7e9551a2bf3c075a719d67edda2b566 348 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 170 338 4.5E-51 T 29-03-2018 IPR001570 Peptidase M4, C-terminal GO:0004222 SMALA_RS12880 e7e9551a2bf3c075a719d67edda2b566 348 Gene3D G3DSA:1.10.390.10 172 339 6.6E-57 T 29-03-2018 SMALA_RS12880 e7e9551a2bf3c075a719d67edda2b566 348 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 60 167 3.7E-27 T 29-03-2018 IPR013856 Peptidase M4 domain GO:0004222 SMALA_RS21570 3aee6cadfc4d0c21a4c14682e8a2a777 412 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 133 283 5.1E-27 T 29-03-2018 SMALA_RS21570 3aee6cadfc4d0c21a4c14682e8a2a777 412 Gene3D G3DSA:3.40.50.150 51 316 1.0E-33 T 29-03-2018 SMALA_RS21570 3aee6cadfc4d0c21a4c14682e8a2a777 412 SUPERFAMILY SSF53335 50 252 1.88E-29 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS39045 94dde6353eef68072008ee6dc06f5e6b 277 Pfam PF09339 IclR helix-turn-helix domain 23 69 3.2E-15 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMALA_RS39045 94dde6353eef68072008ee6dc06f5e6b 277 Gene3D G3DSA:3.30.450.40 93 269 7.7E-43 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS39045 94dde6353eef68072008ee6dc06f5e6b 277 SUPERFAMILY SSF55781 97 263 6.21E-41 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS39045 94dde6353eef68072008ee6dc06f5e6b 277 SMART SM00346 23 109 4.1E-15 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMALA_RS39045 94dde6353eef68072008ee6dc06f5e6b 277 Gene3D G3DSA:1.10.10.10 19 92 8.2E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS39045 94dde6353eef68072008ee6dc06f5e6b 277 Pfam PF01614 Bacterial transcriptional regulator 137 261 1.4E-26 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal SMALA_RS39045 94dde6353eef68072008ee6dc06f5e6b 277 SUPERFAMILY SSF46785 23 91 3.63E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS19725 3169d562f50d5c863a96c80376c2af10 376 SMART SM00480 17 370 1.4E-138 T 29-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMALA_RS19725 3169d562f50d5c863a96c80376c2af10 376 Gene3D G3DSA:3.10.150.10 1 121 3.3E-33 T 29-03-2018 SMALA_RS19725 3169d562f50d5c863a96c80376c2af10 376 SUPERFAMILY SSF55979 249 374 2.08E-29 T 29-03-2018 SMALA_RS19725 3169d562f50d5c863a96c80376c2af10 376 SUPERFAMILY SSF55979 126 249 2.26E-17 T 29-03-2018 SMALA_RS19725 3169d562f50d5c863a96c80376c2af10 376 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 248 373 1.4E-35 T 29-03-2018 IPR022635 DNA polymerase III, beta chain, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMALA_RS19725 3169d562f50d5c863a96c80376c2af10 376 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 374 3.9E-89 T 29-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMALA_RS19725 3169d562f50d5c863a96c80376c2af10 376 PIRSF PIRSF000804 1 375 5.5E-93 T 29-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMALA_RS19725 3169d562f50d5c863a96c80376c2af10 376 SUPERFAMILY SSF55979 2 119 2.33E-24 T 29-03-2018 SMALA_RS19725 3169d562f50d5c863a96c80376c2af10 376 Gene3D G3DSA:3.10.150.10 251 374 5.8E-31 T 29-03-2018 SMALA_RS19725 3169d562f50d5c863a96c80376c2af10 376 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 2 118 9.9E-38 T 29-03-2018 IPR022634 DNA polymerase III, beta chain, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMALA_RS19725 3169d562f50d5c863a96c80376c2af10 376 Gene3D G3DSA:3.10.150.10 122 250 2.2E-30 T 29-03-2018 SMALA_RS19725 3169d562f50d5c863a96c80376c2af10 376 Pfam PF02767 DNA polymerase III beta subunit, central domain 127 246 1.5E-31 T 29-03-2018 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMALA_RS30045 2c186ea7b5018775ecccc4dfce2c711d 883 SMART SM00642 8 752 1.6E-7 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SMALA_RS30045 2c186ea7b5018775ecccc4dfce2c711d 883 TIGRFAM TIGR02401 trehalose_TreY: malto-oligosyltrehalose synthase 8 882 1.8E-247 T 29-03-2018 IPR012767 Maltooligosyl trehalose synthase KEGG: 00500+5.4.99.15|MetaCyc: PWY-2661 SMALA_RS30045 2c186ea7b5018775ecccc4dfce2c711d 883 SUPERFAMILY SSF51445 8 261 3.34E-111 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS30045 2c186ea7b5018775ecccc4dfce2c711d 883 SUPERFAMILY SSF51445 302 431 3.34E-111 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS30045 2c186ea7b5018775ecccc4dfce2c711d 883 SUPERFAMILY SSF51445 503 758 3.34E-111 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS30045 2c186ea7b5018775ecccc4dfce2c711d 883 Gene3D G3DSA:3.20.20.80 15 760 6.0E-100 T 29-03-2018 SMALA_RS30045 2c186ea7b5018775ecccc4dfce2c711d 883 Pfam PF00128 Alpha amylase, catalytic domain 29 99 1.8E-13 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SMALA_RS07345 0594ee84c7789c875d94e379bc637fdb 278 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 95 269 6.1E-25 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS07345 0594ee84c7789c875d94e379bc637fdb 278 Gene3D G3DSA:1.10.3720.10 1 265 4.0E-41 T 29-03-2018 SMALA_RS07345 0594ee84c7789c875d94e379bc637fdb 278 SUPERFAMILY SSF161098 72 259 6.15E-25 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS17760 32136e45dfe0499b5d81814f3633871b 181 Gene3D G3DSA:3.40.1410.10 13 176 1.3E-38 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMALA_RS17760 32136e45dfe0499b5d81814f3633871b 181 Pfam PF07702 UTRA domain 33 171 2.3E-26 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMALA_RS17760 32136e45dfe0499b5d81814f3633871b 181 SMART SM00866 32 173 1.3E-21 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMALA_RS17760 32136e45dfe0499b5d81814f3633871b 181 SUPERFAMILY SSF64288 28 178 1.86E-33 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMALA_RS32020 6bbbaa605d018f7bd5fbc18d88818544 168 Gene3D G3DSA:3.30.565.10 23 167 5.7E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS32020 6bbbaa605d018f7bd5fbc18d88818544 168 Pfam PF13581 Histidine kinase-like ATPase domain 33 150 1.3E-12 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS32020 6bbbaa605d018f7bd5fbc18d88818544 168 SUPERFAMILY SSF55874 42 157 6.02E-13 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS13825 092ddd17c7b0538ff7b7da04c0305fe9 219 Gene3D G3DSA:3.40.50.2300 15 140 7.3E-39 T 29-03-2018 SMALA_RS13825 092ddd17c7b0538ff7b7da04c0305fe9 219 SMART SM00448 16 129 7.2E-32 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS13825 092ddd17c7b0538ff7b7da04c0305fe9 219 SMART SM00421 155 212 1.3E-25 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS13825 092ddd17c7b0538ff7b7da04c0305fe9 219 ProSitePatterns PS00622 LuxR-type HTH domain signature. 172 199 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS13825 092ddd17c7b0538ff7b7da04c0305fe9 219 SUPERFAMILY SSF52172 15 145 1.85E-34 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS13825 092ddd17c7b0538ff7b7da04c0305fe9 219 Pfam PF00072 Response regulator receiver domain 18 130 2.9E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS13825 092ddd17c7b0538ff7b7da04c0305fe9 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 188 1.3E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS13825 092ddd17c7b0538ff7b7da04c0305fe9 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 188 200 1.3E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS13825 092ddd17c7b0538ff7b7da04c0305fe9 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 172 1.3E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS13825 092ddd17c7b0538ff7b7da04c0305fe9 219 Pfam PF00196 Bacterial regulatory proteins, luxR family 157 211 6.9E-17 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS13825 092ddd17c7b0538ff7b7da04c0305fe9 219 Gene3D G3DSA:1.10.10.10 141 219 1.9E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS13825 092ddd17c7b0538ff7b7da04c0305fe9 219 SUPERFAMILY SSF46894 152 218 5.78E-21 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS00155 d72b5b3df452cf21b10a90d6e694e5a0 189 SUPERFAMILY SSF46689 5 72 8.48E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS00155 d72b5b3df452cf21b10a90d6e694e5a0 189 Gene3D G3DSA:1.10.10.60 2 67 1.8E-10 T 29-03-2018 SMALA_RS00155 d72b5b3df452cf21b10a90d6e694e5a0 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 46 3.0E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS00155 d72b5b3df452cf21b10a90d6e694e5a0 189 Pfam PF13305 WHG domain 84 159 4.2E-7 T 29-03-2018 IPR025996 WHG domain SMALA_RS00155 d72b5b3df452cf21b10a90d6e694e5a0 189 Gene3D G3DSA:1.10.357.10 72 189 6.9E-23 T 29-03-2018 SMALA_RS00155 d72b5b3df452cf21b10a90d6e694e5a0 189 SUPERFAMILY SSF48498 78 181 3.41E-20 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS18885 3ca38d8009dbdc8fe0669ff6eaa69794 135 PRINTS PR00502 NUDIX hydrolase family signature 25 39 5.3E-5 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMALA_RS18885 3ca38d8009dbdc8fe0669ff6eaa69794 135 PRINTS PR00502 NUDIX hydrolase family signature 39 54 5.3E-5 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMALA_RS18885 3ca38d8009dbdc8fe0669ff6eaa69794 135 Gene3D G3DSA:3.90.79.10 1 122 1.9E-23 T 29-03-2018 SMALA_RS18885 3ca38d8009dbdc8fe0669ff6eaa69794 135 Pfam PF00293 NUDIX domain 2 107 2.2E-16 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SMALA_RS18885 3ca38d8009dbdc8fe0669ff6eaa69794 135 SUPERFAMILY SSF55811 1 114 5.82E-27 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMALA_RS18885 3ca38d8009dbdc8fe0669ff6eaa69794 135 ProSitePatterns PS00893 Nudix box signature. 30 51 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 SMALA_RS22295 c5b720f5b36c1e6a4df5cbff2a2747d0 133 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 1 101 18.288 T 29-03-2018 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 SMALA_RS22295 c5b720f5b36c1e6a4df5cbff2a2747d0 133 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 8 97 2.3E-25 T 29-03-2018 SMALA_RS24945 30d46784786765418fc3447bbf6854d0 179 Pfam PF14030 Protein of unknown function (DUF4245) 2 174 3.5E-50 T 29-03-2018 IPR025339 Protein of unknown function DUF4245 SMALA_RS29845 19d991b747163975a35d6f63145e3ce5 368 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 26 356 2.9E-124 T 29-03-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 SMALA_RS29845 19d991b747163975a35d6f63145e3ce5 368 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 23 359 47.895 T 29-03-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 SMALA_RS29845 19d991b747163975a35d6f63145e3ce5 368 SUPERFAMILY SSF51726 25 359 3.53E-107 T 29-03-2018 SMALA_RS29845 19d991b747163975a35d6f63145e3ce5 368 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 39 48 - T 29-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 SMALA_RS29845 19d991b747163975a35d6f63145e3ce5 368 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 22 357 7.3E-130 T 29-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 SMALA_RS29845 19d991b747163975a35d6f63145e3ce5 368 Gene3D G3DSA:3.20.20.210 21 360 7.9E-105 T 29-03-2018 SMALA_RS29845 19d991b747163975a35d6f63145e3ce5 368 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 156 172 - T 29-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 SMALA_RS24250 be3e9e81eed26b17f141806c0d21b12b 317 SUPERFAMILY SSF161098 91 295 7.98E-19 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS24250 be3e9e81eed26b17f141806c0d21b12b 317 Gene3D G3DSA:1.10.3720.10 3 301 5.1E-40 T 29-03-2018 SMALA_RS24250 be3e9e81eed26b17f141806c0d21b12b 317 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 312 5.5E-39 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS37200 612f20bd95cc243c527c05ff9f953ec9 791 SMART SM00421 715 772 1.8E-19 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS37200 612f20bd95cc243c527c05ff9f953ec9 791 Pfam PF00196 Bacterial regulatory proteins, luxR family 717 771 1.2E-15 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS37200 612f20bd95cc243c527c05ff9f953ec9 791 Gene3D G3DSA:3.40.50.300 7 156 2.9E-13 T 29-03-2018 SMALA_RS37200 612f20bd95cc243c527c05ff9f953ec9 791 Pfam PF13401 AAA domain 42 135 1.4E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS37200 612f20bd95cc243c527c05ff9f953ec9 791 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 748 760 2.6E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS37200 612f20bd95cc243c527c05ff9f953ec9 791 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 718 732 2.6E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS37200 612f20bd95cc243c527c05ff9f953ec9 791 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 732 748 2.6E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS37200 612f20bd95cc243c527c05ff9f953ec9 791 SUPERFAMILY SSF46894 712 775 3.74E-17 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS37200 612f20bd95cc243c527c05ff9f953ec9 791 Gene3D G3DSA:1.10.10.10 707 784 4.8E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS37200 612f20bd95cc243c527c05ff9f953ec9 791 SUPERFAMILY SSF52540 17 277 2.85E-21 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS37200 612f20bd95cc243c527c05ff9f953ec9 791 Gene3D G3DSA:1.25.40.10 492 702 1.1E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS37200 612f20bd95cc243c527c05ff9f953ec9 791 SUPERFAMILY SSF48452 501 652 1.73E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS37200 612f20bd95cc243c527c05ff9f953ec9 791 PRINTS PR00364 Disease resistance protein signature 112 126 2.4E-6 T 29-03-2018 SMALA_RS37200 612f20bd95cc243c527c05ff9f953ec9 791 PRINTS PR00364 Disease resistance protein signature 221 235 2.4E-6 T 29-03-2018 SMALA_RS37200 612f20bd95cc243c527c05ff9f953ec9 791 PRINTS PR00364 Disease resistance protein signature 43 58 2.4E-6 T 29-03-2018 SMALA_RS19340 72c7330fbdc414e761f79e45ffb50493 514 Gene3D G3DSA:1.20.1250.20 1 188 7.4E-31 T 29-03-2018 SMALA_RS19340 72c7330fbdc414e761f79e45ffb50493 514 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 10 486 1.9E-75 T 29-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 SMALA_RS19340 72c7330fbdc414e761f79e45ffb50493 514 Pfam PF07690 Major Facilitator Superfamily 12 403 4.5E-52 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS19340 72c7330fbdc414e761f79e45ffb50493 514 Gene3D G3DSA:1.20.1250.20 245 507 1.9E-30 T 29-03-2018 SMALA_RS19340 72c7330fbdc414e761f79e45ffb50493 514 SUPERFAMILY SSF103473 4 196 7.19E-67 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS19340 72c7330fbdc414e761f79e45ffb50493 514 SUPERFAMILY SSF103473 467 493 7.19E-67 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS19340 72c7330fbdc414e761f79e45ffb50493 514 SUPERFAMILY SSF103473 242 413 7.19E-67 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS19340 72c7330fbdc414e761f79e45ffb50493 514 PRINTS PR01036 Tetracycline resistance protein TetB signature 295 319 3.4E-9 T 29-03-2018 SMALA_RS19340 72c7330fbdc414e761f79e45ffb50493 514 PRINTS PR01036 Tetracycline resistance protein TetB signature 10 34 3.4E-9 T 29-03-2018 SMALA_RS19340 72c7330fbdc414e761f79e45ffb50493 514 PRINTS PR01036 Tetracycline resistance protein TetB signature 101 121 3.4E-9 T 29-03-2018 SMALA_RS19340 72c7330fbdc414e761f79e45ffb50493 514 PRINTS PR01036 Tetracycline resistance protein TetB signature 131 155 3.4E-9 T 29-03-2018 SMALA_RS19340 72c7330fbdc414e761f79e45ffb50493 514 PRINTS PR01036 Tetracycline resistance protein TetB signature 394 413 3.4E-9 T 29-03-2018 SMALA_RS41470 a81a9eac057247c53576a432e276ab01 2841 SUPERFAMILY SSF51735 481 680 8.44E-30 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS41470 a81a9eac057247c53576a432e276ab01 2841 SMART SM01294 2751 2827 4.4E-5 T 29-03-2018 SMALA_RS41470 a81a9eac057247c53576a432e276ab01 2841 SMART SM01294 965 1032 9.2E-5 T 29-03-2018 SMALA_RS41470 a81a9eac057247c53576a432e276ab01 2841 Pfam PF14765 Polyketide synthase dehydratase 1975 2264 2.9E-54 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS41470 a81a9eac057247c53576a432e276ab01 2841 SUPERFAMILY SSF47336 1078 1093 3.53E-18 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS41470 a81a9eac057247c53576a432e276ab01 2841 SUPERFAMILY SSF47336 959 1037 3.53E-18 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS41470 a81a9eac057247c53576a432e276ab01 2841 Gene3D G3DSA:3.40.366.10 1601 1743 4.0E-48 T 29-03-2018 SMALA_RS41470 a81a9eac057247c53576a432e276ab01 2841 SUPERFAMILY SSF53901 32 386 1.39E-81 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS41470 a81a9eac057247c53576a432e276ab01 2841 SUPERFAMILY SSF47336 2744 2834 4.19E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS41470 a81a9eac057247c53576a432e276ab01 2841 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1608 1904 9.2E-111 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS41470 a81a9eac057247c53576a432e276ab01 2841 Pfam PF00550 Phosphopantetheine attachment site 968 1032 1.9E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS41470 a81a9eac057247c53576a432e276ab01 2841 Pfam PF00550 Phosphopantetheine attachment site 2779 2827 1.0E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS41470 a81a9eac057247c53576a432e276ab01 2841 Gene3D G3DSA:3.40.47.10 1341 1502 2.3E-52 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS41470 a81a9eac057247c53576a432e276ab01 2841 Gene3D G3DSA:3.40.47.10 280 441 2.3E-52 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS41470 a81a9eac057247c53576a432e276ab01 2841 Pfam PF00698 Acyl transferase domain 1607 1921 5.0E-59 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS41470 a81a9eac057247c53576a432e276ab01 2841 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1239 1255 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS41470 a81a9eac057247c53576a432e276ab01 2841 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2486 2663 1.1E-54 T 29-03-2018 SMALA_RS41470 a81a9eac057247c53576a432e276ab01 2841 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 700 882 7.7E-44 T 29-03-2018 SMALA_RS41470 a81a9eac057247c53576a432e276ab01 2841 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 178 194 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS41470 a81a9eac057247c53576a432e276ab01 2841 Gene3D G3DSA:1.10.1200.10 957 1074 2.3E-19 T 29-03-2018 SMALA_RS41470 a81a9eac057247c53576a432e276ab01 2841 SMART SM00825 Beta-ketoacyl synthase 1080 1504 9.1E-172 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS41470 a81a9eac057247c53576a432e276ab01 2841 SMART SM00825 Beta-ketoacyl synthase 36 443 4.2E-163 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS41470 a81a9eac057247c53576a432e276ab01 2841 Gene3D G3DSA:3.40.47.10 1080 1339 1.0E-75 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS41470 a81a9eac057247c53576a432e276ab01 2841 SUPERFAMILY SSF51735 2290 2472 5.12E-21 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS41470 a81a9eac057247c53576a432e276ab01 2841 Gene3D G3DSA:3.40.50.720 2478 2731 5.8E-49 T 29-03-2018 SMALA_RS41470 a81a9eac057247c53576a432e276ab01 2841 Gene3D G3DSA:3.40.50.720 694 949 3.0E-50 T 29-03-2018 SMALA_RS41470 a81a9eac057247c53576a432e276ab01 2841 SUPERFAMILY SSF52151 1798 1894 1.1E-68 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS41470 a81a9eac057247c53576a432e276ab01 2841 SUPERFAMILY SSF52151 1604 1733 1.1E-68 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS41470 a81a9eac057247c53576a432e276ab01 2841 SMART SM00823 Phosphopantetheine attachment site 2750 2831 4.5E-17 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS41470 a81a9eac057247c53576a432e276ab01 2841 SMART SM00823 Phosphopantetheine attachment site 964 1036 7.1E-20 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS41470 a81a9eac057247c53576a432e276ab01 2841 Pfam PF08659 KR domain 700 880 1.4E-58 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS41470 a81a9eac057247c53576a432e276ab01 2841 Pfam PF08659 KR domain 2486 2661 1.6E-60 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS41470 a81a9eac057247c53576a432e276ab01 2841 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2786 2801 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS41470 a81a9eac057247c53576a432e276ab01 2841 SMART SM00826 1973 2145 6.9E-24 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS41470 a81a9eac057247c53576a432e276ab01 2841 Gene3D G3DSA:3.30.70.250 1744 1788 3.0E-19 T 29-03-2018 SMALA_RS41470 a81a9eac057247c53576a432e276ab01 2841 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 393 451 1.0E-7 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS41470 a81a9eac057247c53576a432e276ab01 2841 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1454 1566 2.4E-16 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS41470 a81a9eac057247c53576a432e276ab01 2841 Gene3D G3DSA:1.10.1200.10 2732 2839 2.9E-15 T 29-03-2018 SMALA_RS41470 a81a9eac057247c53576a432e276ab01 2841 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1334 1451 7.3E-36 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS41470 a81a9eac057247c53576a432e276ab01 2841 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 273 390 7.3E-36 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS41470 a81a9eac057247c53576a432e276ab01 2841 SUPERFAMILY SSF51735 2484 2719 1.85E-45 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS41470 a81a9eac057247c53576a432e276ab01 2841 Gene3D G3DSA:3.40.47.10 26 277 4.9E-76 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS41470 a81a9eac057247c53576a432e276ab01 2841 SUPERFAMILY SSF51735 697 949 2.09E-45 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS41470 a81a9eac057247c53576a432e276ab01 2841 Gene3D G3DSA:3.40.50.10090 496 600 0.024 T 29-03-2018 SMALA_RS41470 a81a9eac057247c53576a432e276ab01 2841 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 265 7.0E-76 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS41470 a81a9eac057247c53576a432e276ab01 2841 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1079 1326 1.3E-82 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS41470 a81a9eac057247c53576a432e276ab01 2841 Gene3D G3DSA:3.40.366.10 1789 1898 1.8E-20 T 29-03-2018 SMALA_RS41470 a81a9eac057247c53576a432e276ab01 2841 SUPERFAMILY SSF53901 1077 1447 1.71E-83 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS41470 a81a9eac057247c53576a432e276ab01 2841 SUPERFAMILY SSF55048 1732 1797 1.12E-12 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS09245 336c2d18f294ab5d19afe9c4859c07f7 420 PIRSF PIRSF000521 4 135 2.1E-6 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMALA_RS09245 336c2d18f294ab5d19afe9c4859c07f7 420 PIRSF PIRSF000521 189 419 8.3E-29 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMALA_RS09245 336c2d18f294ab5d19afe9c4859c07f7 420 PIRSF PIRSF000521 128 166 0.21 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMALA_RS09245 336c2d18f294ab5d19afe9c4859c07f7 420 TIGRFAM TIGR00709 dat: 2,4-diaminobutyrate 4-transaminase 8 419 3.0E-134 T 29-03-2018 IPR004637 2,4-diaminobutyrate 4-transaminase GO:0008483|GO:0009058 KEGG: 00260+2.6.1.76|MetaCyc: PWY-6409|MetaCyc: PWY-6562|MetaCyc: PWY-761|MetaCyc: PWY-7855 SMALA_RS09245 336c2d18f294ab5d19afe9c4859c07f7 420 Pfam PF00202 Aminotransferase class-III 27 416 1.5E-75 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMALA_RS09245 336c2d18f294ab5d19afe9c4859c07f7 420 Gene3D G3DSA:3.90.1150.10 310 420 4.4E-21 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS09245 336c2d18f294ab5d19afe9c4859c07f7 420 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 239 275 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMALA_RS09245 336c2d18f294ab5d19afe9c4859c07f7 420 SUPERFAMILY SSF53383 15 417 9.11E-106 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS09245 336c2d18f294ab5d19afe9c4859c07f7 420 TIGRFAM TIGR02407 ectoine_ectB: diaminobutyrate--2-oxoglutarate aminotransferase 10 417 1.1E-198 T 29-03-2018 IPR012773 Ectoine biosynthetic protein GO:0019491|GO:0030170|GO:0047307 KEGG: 00260+2.6.1.76|MetaCyc: PWY-6409|MetaCyc: PWY-6562|MetaCyc: PWY-761|MetaCyc: PWY-7855 SMALA_RS09245 336c2d18f294ab5d19afe9c4859c07f7 420 Gene3D G3DSA:3.90.1150.10 7 165 2.9E-36 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS09245 336c2d18f294ab5d19afe9c4859c07f7 420 Gene3D G3DSA:3.40.640.10 186 309 7.7E-31 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS38225 4f8c47ae6af8107c5588fe6014ef75a8 588 Gene3D G3DSA:1.10.540.10 19 131 7.4E-8 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS38225 4f8c47ae6af8107c5588fe6014ef75a8 588 SUPERFAMILY SSF47203 244 393 1.27E-16 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMALA_RS38225 4f8c47ae6af8107c5588fe6014ef75a8 588 Gene3D G3DSA:2.40.110.10 132 234 3.6E-25 T 29-03-2018 SMALA_RS38225 4f8c47ae6af8107c5588fe6014ef75a8 588 Gene3D G3DSA:1.20.140.10 235 405 6.1E-24 T 29-03-2018 SMALA_RS38225 4f8c47ae6af8107c5588fe6014ef75a8 588 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 133 230 1.2E-15 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 SMALA_RS38225 4f8c47ae6af8107c5588fe6014ef75a8 588 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 243 392 2.1E-16 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMALA_RS38225 4f8c47ae6af8107c5588fe6014ef75a8 588 SUPERFAMILY SSF56645 33 243 1.44E-41 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMALA_RS39330 b420b8f472e2d6e262df1f19abfadaeb 297 Pfam PF00248 Aldo/keto reductase family 15 287 1.8E-38 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS39330 b420b8f472e2d6e262df1f19abfadaeb 297 PRINTS PR00069 Aldo-keto reductase signature 147 164 6.6E-7 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMALA_RS39330 b420b8f472e2d6e262df1f19abfadaeb 297 PRINTS PR00069 Aldo-keto reductase signature 40 64 6.6E-7 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMALA_RS39330 b420b8f472e2d6e262df1f19abfadaeb 297 PRINTS PR00069 Aldo-keto reductase signature 221 245 6.6E-7 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMALA_RS39330 b420b8f472e2d6e262df1f19abfadaeb 297 Gene3D G3DSA:3.20.20.100 1 293 1.2E-57 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS39330 b420b8f472e2d6e262df1f19abfadaeb 297 SUPERFAMILY SSF51430 10 287 1.44E-55 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS24160 aeebf8ca9936c6e2ca051417a6cb7970 103 PIRSF PIRSF028743 1 103 1.3E-35 T 29-03-2018 IPR008634 Gas vesicle protein GvpO GO:0031412 SMALA_RS24160 aeebf8ca9936c6e2ca051417a6cb7970 103 Pfam PF05800 Gas vesicle synthesis protein GvpO 11 101 7.5E-36 T 29-03-2018 IPR008634 Gas vesicle protein GvpO GO:0031412 SMALA_RS35880 3df8795ffb1101ebd28b495c1dd36621 252 TIGRFAM TIGR00715 precor6x_red: precorrin-6x reductase 8 247 1.9E-46 T 29-03-2018 IPR003723 Precorrin-6x reductase GO:0009236|GO:0016994|GO:0055114 SMALA_RS35880 3df8795ffb1101ebd28b495c1dd36621 252 Gene3D G3DSA:3.40.50.2300 73 249 3.5E-19 T 29-03-2018 SMALA_RS35880 3df8795ffb1101ebd28b495c1dd36621 252 Pfam PF02571 Precorrin-6x reductase CbiJ/CobK 8 247 2.4E-71 T 29-03-2018 IPR003723 Precorrin-6x reductase GO:0009236|GO:0016994|GO:0055114 SMALA_RS08525 49183adcce494b4aa3dc043612ba80b7 301 PIRSF PIRSF001134 8 301 4.2E-92 T 29-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMALA_RS08525 49183adcce494b4aa3dc043612ba80b7 301 Pfam PF02983 Alpha-lytic protease prodomain 47 99 2.4E-10 T 29-03-2018 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 SMALA_RS08525 49183adcce494b4aa3dc043612ba80b7 301 Gene3D G3DSA:3.30.300.50 12 111 1.6E-16 T 29-03-2018 IPR035070 Streptogrisin prodomain SMALA_RS08525 49183adcce494b4aa3dc043612ba80b7 301 Gene3D G3DSA:2.40.10.10 117 201 1.5E-22 T 29-03-2018 SMALA_RS08525 49183adcce494b4aa3dc043612ba80b7 301 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 251 262 - T 29-03-2018 IPR033116 Serine proteases, trypsin family, serine active site SMALA_RS08525 49183adcce494b4aa3dc043612ba80b7 301 Gene3D G3DSA:2.40.10.10 202 288 5.9E-23 T 29-03-2018 SMALA_RS08525 49183adcce494b4aa3dc043612ba80b7 301 Pfam PF00089 Trypsin 117 291 9.2E-12 T 29-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 SMALA_RS08525 49183adcce494b4aa3dc043612ba80b7 301 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 144 158 1.9E-49 T 29-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMALA_RS08525 49183adcce494b4aa3dc043612ba80b7 301 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 266 280 1.9E-49 T 29-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMALA_RS08525 49183adcce494b4aa3dc043612ba80b7 301 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 222 239 1.9E-49 T 29-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMALA_RS08525 49183adcce494b4aa3dc043612ba80b7 301 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 242 265 1.9E-49 T 29-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMALA_RS08525 49183adcce494b4aa3dc043612ba80b7 301 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 201 221 1.9E-49 T 29-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMALA_RS08525 49183adcce494b4aa3dc043612ba80b7 301 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 146 151 - T 29-03-2018 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 SMALA_RS08525 49183adcce494b4aa3dc043612ba80b7 301 SUPERFAMILY SSF50494 124 294 1.04E-39 T 29-03-2018 IPR009003 Peptidase S1, PA clan SMALA_RS37715 67c984b9371d8e2230029ffeaa8ca3aa 497 Pfam PF04984 Phage tail sheath protein subtilisin-like domain 207 379 4.7E-11 T 29-03-2018 IPR035089 Tail sheath protein, subtilisin-like domain SMALA_RS37715 67c984b9371d8e2230029ffeaa8ca3aa 497 Pfam PF17482 Phage tail sheath C-terminal domain 381 484 6.5E-5 T 29-03-2018 IPR020287 Tail sheath protein, C-terminal domain SMALA_RS05305 9cbf5c9a04d5371403318a6c1362f94e 362 SUPERFAMILY SSF55347 133 292 2.13E-28 T 29-03-2018 SMALA_RS05305 9cbf5c9a04d5371403318a6c1362f94e 362 Gene3D G3DSA:3.30.360.10 140 355 3.9E-34 T 29-03-2018 SMALA_RS05305 9cbf5c9a04d5371403318a6c1362f94e 362 SUPERFAMILY SSF51735 2 155 4.16E-38 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS05305 9cbf5c9a04d5371403318a6c1362f94e 362 Gene3D G3DSA:3.40.50.720 1 139 2.1E-30 T 29-03-2018 SMALA_RS05305 9cbf5c9a04d5371403318a6c1362f94e 362 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 5 122 7.0E-19 T 29-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 SMALA_RS41495 545575b191ccfbc35f1014d59b6ed776 456 Pfam PF05977 Transmembrane secretion effector 45 432 3.5E-26 T 29-03-2018 IPR010290 Transmembrane secretion effector SMALA_RS41495 545575b191ccfbc35f1014d59b6ed776 456 Gene3D G3DSA:1.20.1250.20 250 450 1.6E-18 T 29-03-2018 SMALA_RS41495 545575b191ccfbc35f1014d59b6ed776 456 Gene3D G3DSA:1.20.1250.20 37 229 2.5E-14 T 29-03-2018 SMALA_RS41495 545575b191ccfbc35f1014d59b6ed776 456 SUPERFAMILY SSF103473 46 431 6.02E-41 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS27545 be0f37fc6de91a4cf10c7d4d14c4a0f2 334 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 33 69 4.1E-12 T 29-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain SMALA_RS27545 be0f37fc6de91a4cf10c7d4d14c4a0f2 334 SUPERFAMILY SSF161098 117 315 1.27E-30 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS27545 be0f37fc6de91a4cf10c7d4d14c4a0f2 334 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 140 331 1.4E-28 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS27545 be0f37fc6de91a4cf10c7d4d14c4a0f2 334 Gene3D G3DSA:1.10.3720.10 37 322 1.2E-51 T 29-03-2018 SMALA_RS17425 0e437972803e1c0031d0aae0b9fc8176 699 Gene3D G3DSA:3.40.50.300 192 529 1.3E-28 T 29-03-2018 SMALA_RS17425 0e437972803e1c0031d0aae0b9fc8176 699 SUPERFAMILY SSF52540 297 317 1.98E-41 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS17425 0e437972803e1c0031d0aae0b9fc8176 699 SUPERFAMILY SSF52540 454 690 1.98E-41 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS17425 0e437972803e1c0031d0aae0b9fc8176 699 SUPERFAMILY SSF52540 186 265 1.98E-41 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS17425 0e437972803e1c0031d0aae0b9fc8176 699 SUPERFAMILY SSF52540 347 358 1.98E-41 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS17425 0e437972803e1c0031d0aae0b9fc8176 699 Gene3D G3DSA:3.40.50.300 534 698 4.7E-13 T 29-03-2018 SMALA_RS17425 0e437972803e1c0031d0aae0b9fc8176 699 Pfam PF13245 AAA domain 198 507 1.1E-6 T 29-03-2018 SMALA_RS23105 4ac164153e2532a8a6d8cbdeb247fd50 392 SUPERFAMILY SSF53901 235 364 5.24E-23 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS23105 4ac164153e2532a8a6d8cbdeb247fd50 392 SUPERFAMILY SSF53901 8 228 5.21E-19 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS23105 4ac164153e2532a8a6d8cbdeb247fd50 392 Pfam PF02803 Thiolase, C-terminal domain 254 359 9.4E-7 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 SMALA_RS23105 4ac164153e2532a8a6d8cbdeb247fd50 392 Gene3D G3DSA:3.40.47.10 147 386 6.5E-32 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS23105 4ac164153e2532a8a6d8cbdeb247fd50 392 Gene3D G3DSA:3.40.47.10 10 134 0.0075 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS23105 4ac164153e2532a8a6d8cbdeb247fd50 392 PIRSF PIRSF000429 6 380 1.7E-27 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 SMALA_RS02080 73449fc2ecd3133351b9dbeb094f0bf3 354 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 228 240 - T 29-03-2018 IPR033749 Polyprenyl synthetase, conserved site SMALA_RS02080 73449fc2ecd3133351b9dbeb094f0bf3 354 SUPERFAMILY SSF48576 59 353 3.04E-74 T 29-03-2018 IPR008949 Isoprenoid synthase domain SMALA_RS02080 73449fc2ecd3133351b9dbeb094f0bf3 354 Gene3D G3DSA:1.10.600.10 3 354 4.1E-92 T 29-03-2018 IPR008949 Isoprenoid synthase domain SMALA_RS02080 73449fc2ecd3133351b9dbeb094f0bf3 354 Pfam PF00348 Polyprenyl synthetase 59 272 4.1E-53 T 29-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 SMALA_RS02665 5d41ddb1fe3bfc434b0eed3367e7688f 733 Pfam PF00754 F5/8 type C domain 601 725 1.3E-16 T 29-03-2018 IPR000421 Coagulation factor 5/8 C-terminal domain SMALA_RS02665 5d41ddb1fe3bfc434b0eed3367e7688f 733 SUPERFAMILY SSF51126 184 520 9.0E-40 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor SMALA_RS02665 5d41ddb1fe3bfc434b0eed3367e7688f 733 Gene3D G3DSA:2.160.20.10 192 572 2.4E-47 T 29-03-2018 IPR012334 Pectin lyase fold SMALA_RS02665 5d41ddb1fe3bfc434b0eed3367e7688f 733 SUPERFAMILY SSF49785 591 729 1.84E-23 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS02665 5d41ddb1fe3bfc434b0eed3367e7688f 733 Gene3D G3DSA:2.60.120.260 49 191 7.8E-8 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS02665 5d41ddb1fe3bfc434b0eed3367e7688f 733 Pfam PF12708 Pectate lyase superfamily protein 200 417 1.5E-15 T 29-03-2018 IPR024535 Pectate lyase superfamily protein SMALA_RS02665 5d41ddb1fe3bfc434b0eed3367e7688f 733 Gene3D G3DSA:2.60.120.260 574 733 4.1E-32 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS02665 5d41ddb1fe3bfc434b0eed3367e7688f 733 SMART SM00710 379 402 510.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat SMALA_RS02665 5d41ddb1fe3bfc434b0eed3367e7688f 733 SMART SM00710 352 374 6800.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat SMALA_RS02665 5d41ddb1fe3bfc434b0eed3367e7688f 733 SMART SM00710 305 326 8700.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat SMALA_RS02665 5d41ddb1fe3bfc434b0eed3367e7688f 733 SMART SM00710 438 469 4100.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat SMALA_RS02665 5d41ddb1fe3bfc434b0eed3367e7688f 733 SMART SM00710 505 525 5300.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat SMALA_RS02665 5d41ddb1fe3bfc434b0eed3367e7688f 733 SMART SM00710 475 497 7000.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat SMALA_RS02665 5d41ddb1fe3bfc434b0eed3367e7688f 733 SMART SM00710 403 427 11.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat SMALA_RS02665 5d41ddb1fe3bfc434b0eed3367e7688f 733 SMART SM00710 328 350 5.1 T 29-03-2018 IPR006626 Parallel beta-helix repeat SMALA_RS01625 ed9e54db124a71dba75ef21fb63decf2 408 TIGRFAM TIGR01821 5aminolev_synth: 5-aminolevulinic acid synthase 9 391 3.9E-162 T 29-03-2018 IPR010961 Tetrapyrrole biosynthesis, 5-aminolevulinic acid synthase GO:0003870|GO:0030170|GO:0033014 KEGG: 00260+2.3.1.37|KEGG: 00860+2.3.1.37|MetaCyc: PWY-5189|MetaCyc: PWY-7536|Reactome: R-HSA-189451 SMALA_RS01625 ed9e54db124a71dba75ef21fb63decf2 408 Gene3D G3DSA:3.40.640.10 120 283 8.7E-58 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS01625 ed9e54db124a71dba75ef21fb63decf2 408 Gene3D G3DSA:3.90.1150.10 40 119 8.5E-7 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS01625 ed9e54db124a71dba75ef21fb63decf2 408 Pfam PF00155 Aminotransferase class I and II 42 383 5.4E-75 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMALA_RS01625 ed9e54db124a71dba75ef21fb63decf2 408 Gene3D G3DSA:3.90.1150.10 284 393 4.4E-23 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS01625 ed9e54db124a71dba75ef21fb63decf2 408 SUPERFAMILY SSF53383 36 390 5.92E-112 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS23695 abc57c6ebf74520b7a26cc911cf90874 361 SUPERFAMILY SSF51905 261 322 3.0E-19 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS23695 abc57c6ebf74520b7a26cc911cf90874 361 SUPERFAMILY SSF51905 129 145 3.0E-19 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS23695 abc57c6ebf74520b7a26cc911cf90874 361 SUPERFAMILY SSF51905 2 92 3.0E-19 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS23695 abc57c6ebf74520b7a26cc911cf90874 361 Gene3D G3DSA:3.50.50.60 197 336 5.6E-5 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS23695 abc57c6ebf74520b7a26cc911cf90874 361 Pfam PF12831 FAD dependent oxidoreductase 4 40 8.9E-7 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS23695 abc57c6ebf74520b7a26cc911cf90874 361 Gene3D G3DSA:3.50.50.60 1 169 1.5E-15 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS23695 abc57c6ebf74520b7a26cc911cf90874 361 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 2.0E-7 T 29-03-2018 SMALA_RS23695 abc57c6ebf74520b7a26cc911cf90874 361 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 137 155 2.0E-7 T 29-03-2018 SMALA_RS23695 abc57c6ebf74520b7a26cc911cf90874 361 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 293 300 2.3E-11 T 29-03-2018 SMALA_RS23695 abc57c6ebf74520b7a26cc911cf90874 361 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 140 149 2.3E-11 T 29-03-2018 SMALA_RS23695 abc57c6ebf74520b7a26cc911cf90874 361 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 2.3E-11 T 29-03-2018 SMALA_RS22135 97b2e7f5f7b1ee0d89ee6d58df56e665 829 SUPERFAMILY SSF53706 229 713 1.69E-83 T 29-03-2018 SMALA_RS22135 97b2e7f5f7b1ee0d89ee6d58df56e665 829 ProSitePatterns PS00643 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. 168 178 - T 29-03-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS22135 97b2e7f5f7b1ee0d89ee6d58df56e665 829 TIGRFAM TIGR01973 NuoG: NADH dehydrogenase (quinone), G subunit 24 675 8.9E-191 T 29-03-2018 IPR010228 NADH:ubiquinone oxidoreductase, subunit G GO:0016651|GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS22135 97b2e7f5f7b1ee0d89ee6d58df56e665 829 Pfam PF00384 Molybdopterin oxidoreductase 295 441 1.3E-10 T 29-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS22135 97b2e7f5f7b1ee0d89ee6d58df56e665 829 Pfam PF00384 Molybdopterin oxidoreductase 526 660 1.3E-9 T 29-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS22135 97b2e7f5f7b1ee0d89ee6d58df56e665 829 Gene3D G3DSA:3.40.50.740 297 463 1.4E-22 T 29-03-2018 SMALA_RS22135 97b2e7f5f7b1ee0d89ee6d58df56e665 829 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 242 289 1.1E-5 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS22135 97b2e7f5f7b1ee0d89ee6d58df56e665 829 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 105 143 5.1E-16 T 29-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS22135 97b2e7f5f7b1ee0d89ee6d58df56e665 829 Pfam PF01568 Molydopterin dinucleotide binding domain 748 803 6.3E-8 T 29-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 SMALA_RS22135 97b2e7f5f7b1ee0d89ee6d58df56e665 829 Gene3D G3DSA:2.20.25.90 235 296 5.1E-10 T 29-03-2018 SMALA_RS22135 97b2e7f5f7b1ee0d89ee6d58df56e665 829 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 21 95 1.8E-18 T 29-03-2018 SMALA_RS22135 97b2e7f5f7b1ee0d89ee6d58df56e665 829 SUPERFAMILY SSF50692 721 802 1.05E-7 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain SMALA_RS22135 97b2e7f5f7b1ee0d89ee6d58df56e665 829 Gene3D G3DSA:3.40.50.740 464 705 3.2E-37 T 29-03-2018 SMALA_RS22135 97b2e7f5f7b1ee0d89ee6d58df56e665 829 Gene3D G3DSA:3.10.20.30 14 183 1.1E-15 T 29-03-2018 IPR012675 Beta-grasp domain SMALA_RS22135 97b2e7f5f7b1ee0d89ee6d58df56e665 829 SUPERFAMILY SSF54292 22 94 3.28E-19 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SMALA_RS22135 97b2e7f5f7b1ee0d89ee6d58df56e665 829 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 51 68 - T 29-03-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS22135 97b2e7f5f7b1ee0d89ee6d58df56e665 829 SUPERFAMILY SSF54862 98 233 7.53E-31 T 29-03-2018 SMALA_RS22135 97b2e7f5f7b1ee0d89ee6d58df56e665 829 SMART SM00929 105 145 3.1E-19 T 29-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS22135 97b2e7f5f7b1ee0d89ee6d58df56e665 829 ProSitePatterns PS00642 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. 120 132 - T 29-03-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS22135 97b2e7f5f7b1ee0d89ee6d58df56e665 829 SMART SM00926 238 292 7.0E-8 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS22135 97b2e7f5f7b1ee0d89ee6d58df56e665 829 Gene3D G3DSA:2.40.40.20 742 824 1.2E-18 T 29-03-2018 SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 SUPERFAMILY SSF55048 1377 1439 1.03E-10 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 SUPERFAMILY SSF52151 3236 3347 4.19E-71 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 SUPERFAMILY SSF52151 3056 3177 4.19E-71 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 Gene3D G3DSA:3.40.50.720 3690 3954 1.8E-54 T 29-03-2018 SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 Gene3D G3DSA:3.40.50.720 2132 2386 6.4E-45 T 29-03-2018 SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 879 895 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 SUPERFAMILY SSF53901 2 141 6.63E-43 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 Gene3D G3DSA:3.40.366.10 1250 1388 3.2E-43 T 29-03-2018 SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4016 4031 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 SUPERFAMILY SSF47336 2435 2544 9.42E-24 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 SUPERFAMILY SSF47336 618 731 4.58E-17 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 Gene3D G3DSA:1.10.1200.10 2434 2530 1.9E-20 T 29-03-2018 SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 SUPERFAMILY SSF53901 2525 2901 2.54E-101 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 Gene3D G3DSA:3.40.366.10 417 542 1.1E-27 T 29-03-2018 SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 Gene3D G3DSA:3.40.366.10 3229 3355 4.6E-28 T 29-03-2018 SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3698 3881 8.1E-58 T 29-03-2018 SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2140 2320 1.2E-60 T 29-03-2018 SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 Gene3D G3DSA:3.40.47.10 2794 2955 6.9E-63 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 Gene3D G3DSA:3.40.47.10 981 1144 1.4E-63 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 Gene3D G3DSA:3.40.47.10 1 142 2.8E-51 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2 90 1.6E-30 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 974 1091 2.1E-43 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2787 2904 6.8E-43 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 SUPERFAMILY SSF51735 3695 3963 1.14E-49 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 93 214 2.4E-15 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2907 3026 4.2E-15 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1094 1215 4.1E-15 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 Gene3D G3DSA:3.40.366.10 231 416 8.8E-55 T 29-03-2018 SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 Gene3D G3DSA:3.40.366.10 3043 3228 1.5E-54 T 29-03-2018 SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 Gene3D G3DSA:3.40.366.10 1435 1558 5.5E-24 T 29-03-2018 SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 SUPERFAMILY SSF51735 3463 3686 9.45E-47 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 SUPERFAMILY SSF47336 3985 4068 8.24E-20 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 SUPERFAMILY SSF51735 1884 2066 2.21E-38 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 SMART SM01294 2438 2505 1.5E-5 T 29-03-2018 SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 SMART SM01294 622 689 5.9E-4 T 29-03-2018 SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 SMART SM01294 3990 4057 0.0011 T 29-03-2018 SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 SUPERFAMILY SSF55048 369 429 2.88E-8 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 246 537 1.2E-115 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 3059 3350 2.9E-114 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1254 1552 2.3E-119 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 Pfam PF14765 Polyketide synthase dehydratase 1622 1873 8.6E-21 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 SUPERFAMILY SSF55048 3182 3242 2.88E-8 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 Pfam PF08659 KR domain 2140 2318 8.9E-58 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 Pfam PF08659 KR domain 3698 3880 2.0E-57 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 Gene3D G3DSA:1.10.1200.10 3968 4067 5.8E-18 T 29-03-2018 SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 SUPERFAMILY SSF52151 1444 1539 4.71E-69 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 SUPERFAMILY SSF52151 1250 1379 4.71E-69 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 SUPERFAMILY SSF51735 2138 2371 1.41E-43 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 SMART SM00825 Beta-ketoacyl synthase 2531 2957 4.0E-222 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 SMART SM00825 Beta-ketoacyl synthase 718 1146 2.7E-232 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 Gene3D G3DSA:3.30.70.250 1389 1434 3.4E-16 T 29-03-2018 SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 ProSitePatterns PS00012 Phosphopantetheine attachment site. 648 663 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 Pfam PF00550 Phosphopantetheine attachment site 3994 4057 4.2E-8 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 Pfam PF00550 Phosphopantetheine attachment site 631 689 1.4E-9 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 Pfam PF00550 Phosphopantetheine attachment site 2439 2505 6.0E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 SUPERFAMILY SSF53901 713 1090 1.24E-104 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 SMART SM00826 1622 1775 3.3E-54 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 2692 2708 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 Gene3D G3DSA:1.10.1200.10 603 698 1.5E-14 T 29-03-2018 SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2529 2779 2.8E-89 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 716 966 2.9E-93 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2464 2479 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 SMART SM00823 Phosphopantetheine attachment site 2437 2509 2.5E-30 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 SMART SM00823 Phosphopantetheine attachment site 621 693 1.7E-21 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 SMART SM00823 Phosphopantetheine attachment site 3989 4061 4.5E-31 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 SUPERFAMILY SSF52151 423 534 1.23E-71 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 SUPERFAMILY SSF52151 244 364 1.23E-71 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 Gene3D G3DSA:3.40.47.10 2531 2791 1.2E-85 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 Gene3D G3DSA:3.40.47.10 709 978 8.9E-87 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 Pfam PF00698 Acyl transferase domain 1252 1572 8.8E-88 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 Pfam PF00698 Acyl transferase domain 245 554 4.1E-53 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 Pfam PF00698 Acyl transferase domain 3058 3367 3.9E-53 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS35960 6c2eff8efcc1161e1d9110deeedabd07 4143 Gene3D G3DSA:3.10.129.10 1629 1745 6.1E-4 T 29-03-2018 SMALA_RS21065 8b5b30a3b81977d65241ef7c1a1d2a81 364 SUPERFAMILY SSF51126 49 353 1.79E-20 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor SMALA_RS21065 8b5b30a3b81977d65241ef7c1a1d2a81 364 Gene3D G3DSA:2.160.20.20 46 233 4.5E-14 T 29-03-2018 IPR012332 P22 tailspike C-terminal domain-like SMALA_RS21065 8b5b30a3b81977d65241ef7c1a1d2a81 364 Gene3D G3DSA:2.160.20.20 234 358 7.4E-9 T 29-03-2018 IPR012332 P22 tailspike C-terminal domain-like SMALA_RS21065 8b5b30a3b81977d65241ef7c1a1d2a81 364 SMART SM00710 213 234 2100.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat SMALA_RS21065 8b5b30a3b81977d65241ef7c1a1d2a81 364 SMART SM00710 317 339 2300.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat SMALA_RS21065 8b5b30a3b81977d65241ef7c1a1d2a81 364 SMART SM00710 182 207 1900.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat SMALA_RS21065 8b5b30a3b81977d65241ef7c1a1d2a81 364 SMART SM00710 291 312 6200.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat SMALA_RS21065 8b5b30a3b81977d65241ef7c1a1d2a81 364 SMART SM00710 160 181 320.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat SMALA_RS21065 8b5b30a3b81977d65241ef7c1a1d2a81 364 SMART SM00710 126 156 2000.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 SUPERFAMILY SSF51735 7918 8108 2.76E-36 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 SUPERFAMILY SSF51735 4816 5054 2.55E-48 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 SUPERFAMILY SSF51735 2955 3216 4.4E-50 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 SMART SM00823 Phosphopantetheine attachment site 6646 6718 4.9E-32 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 SMART SM00823 Phosphopantetheine attachment site 1760 1832 3.1E-32 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 SMART SM00823 Phosphopantetheine attachment site 5104 5176 7.2E-32 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 SMART SM00823 Phosphopantetheine attachment site 8435 8507 8.2E-34 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 SMART SM00823 Phosphopantetheine attachment site 3247 3319 2.7E-31 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 SUPERFAMILY SSF53901 6741 7118 5.77E-106 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3341 3591 2.2E-91 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1861 2109 5.1E-85 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 35 285 6.4E-88 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 5197 5447 1.2E-90 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 6744 6994 1.7E-93 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 SUPERFAMILY SSF51735 8139 8351 2.81E-42 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 SUPERFAMILY SSF52151 565 686 1.6E-75 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 SUPERFAMILY SSF52151 745 855 1.6E-75 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 198 214 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 SUPERFAMILY SSF47336 5099 5212 1.57E-23 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 SUPERFAMILY SSF55048 691 752 1.57E-11 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3274 3289 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 3504 3520 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 SUPERFAMILY SSF47336 1753 1875 8.9E-22 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 SUPERFAMILY SSF47336 8428 8514 4.58E-22 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Gene3D G3DSA:1.10.1200.10 8418 8513 2.2E-22 T 29-03-2018 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 6907 6923 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Gene3D G3DSA:3.40.366.10 2386 2530 4.6E-50 T 29-03-2018 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 SUPERFAMILY SSF52151 2570 2678 9.42E-76 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 SUPERFAMILY SSF52151 2390 2511 9.42E-76 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 ProSitePatterns PS00012 Phosphopantetheine attachment site. 8462 8477 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 SUPERFAMILY SSF51735 1473 1678 2.84E-44 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1787 1802 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Gene3D G3DSA:3.40.366.10 7452 7565 9.4E-27 T 29-03-2018 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Gene3D G3DSA:3.40.366.10 743 868 1.8E-26 T 29-03-2018 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Pfam PF14765 Polyketide synthase dehydratase 7637 7903 4.8E-50 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Pfam PF14765 Polyketide synthase dehydratase 4239 4515 1.1E-55 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Pfam PF14765 Polyketide synthase dehydratase 928 1194 1.6E-50 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Gene3D G3DSA:1.10.1200.10 5097 5195 8.8E-19 T 29-03-2018 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Gene3D G3DSA:1.10.1200.10 6639 6741 1.2E-20 T 29-03-2018 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Gene3D G3DSA:1.10.1200.10 3240 3340 1.1E-19 T 29-03-2018 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Gene3D G3DSA:1.10.1200.10 1753 1859 3.5E-19 T 29-03-2018 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 SUPERFAMILY SSF52151 7274 7395 9.68E-77 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 SUPERFAMILY SSF52151 7454 7558 9.68E-77 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 SUPERFAMILY SSF53901 5193 5569 4.55E-105 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Gene3D G3DSA:3.40.47.10 27 297 5.1E-84 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Gene3D G3DSA:3.40.47.10 5196 5459 3.1E-87 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Gene3D G3DSA:3.40.47.10 6742 7006 2.4E-85 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Gene3D G3DSA:3.40.47.10 3341 3603 7.6E-84 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Gene3D G3DSA:3.40.47.10 1860 2121 6.2E-81 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Gene3D G3DSA:3.30.70.250 702 742 1.7E-18 T 29-03-2018 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Gene3D G3DSA:3.30.70.250 5861 5904 2.1E-17 T 29-03-2018 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Gene3D G3DSA:3.30.70.250 2531 2568 2.1E-18 T 29-03-2018 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Gene3D G3DSA:3.30.70.250 4003 4046 9.6E-19 T 29-03-2018 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Gene3D G3DSA:3.30.70.250 7411 7451 4.8E-18 T 29-03-2018 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 SUPERFAMILY SSF52151 4048 4152 9.68E-76 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 SUPERFAMILY SSF52151 3868 3989 9.68E-76 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Gene3D G3DSA:3.40.47.10 3606 3767 4.0E-64 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Gene3D G3DSA:3.40.47.10 5462 5623 2.8E-62 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Gene3D G3DSA:3.40.47.10 300 461 1.1E-60 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Gene3D G3DSA:3.40.47.10 7009 7170 2.3E-63 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Gene3D G3DSA:3.40.47.10 2124 2285 4.6E-61 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 SUPERFAMILY SSF53901 1859 2232 1.08E-100 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 SUPERFAMILY SSF47336 3242 3356 1.1E-23 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 SMART SM00826 4239 4403 8.5E-81 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 SMART SM00826 928 1091 9.6E-84 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 SMART SM00826 7637 7803 4.5E-78 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 SUPERFAMILY SSF55048 5852 5913 4.32E-11 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 7277 7570 1.2E-127 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 5729 6021 7.6E-126 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 3871 4165 2.0E-128 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 568 860 3.6E-127 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2393 2685 4.1E-127 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Pfam PF00550 Phosphopantetheine attachment site 3249 3315 4.9E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Pfam PF00550 Phosphopantetheine attachment site 6648 6714 4.0E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Pfam PF00550 Phosphopantetheine attachment site 8437 8503 2.6E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Pfam PF00550 Phosphopantetheine attachment site 5106 5172 1.3E-9 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Pfam PF00550 Phosphopantetheine attachment site 1762 1828 1.4E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 ProSitePatterns PS00012 Phosphopantetheine attachment site. 6673 6688 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 3599 3716 5.4E-44 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 293 410 1.3E-41 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 7002 7119 5.0E-45 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2117 2234 9.8E-45 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 5455 5572 5.9E-44 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 ProSitePatterns PS00012 Phosphopantetheine attachment site. 5131 5146 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 5360 5376 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 SMART SM00825 Beta-ketoacyl synthase 6746 7172 8.2E-227 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 SMART SM00825 Beta-ketoacyl synthase 1863 2287 3.1E-209 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 SMART SM00825 Beta-ketoacyl synthase 3343 3769 5.9E-227 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 SMART SM00825 Beta-ketoacyl synthase 5199 5625 7.2E-232 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 SMART SM00825 Beta-ketoacyl synthase 37 463 2.8E-219 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Pfam PF08659 KR domain 4822 5000 9.5E-59 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Pfam PF08659 KR domain 8141 8320 1.5E-54 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Pfam PF08659 KR domain 1475 1653 1.1E-59 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Pfam PF08659 KR domain 2959 3136 3.4E-59 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Pfam PF08659 KR domain 6358 6536 2.3E-60 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Gene3D G3DSA:3.40.50.720 2951 3211 1.0E-54 T 29-03-2018 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Gene3D G3DSA:3.40.50.720 1467 1721 6.3E-46 T 29-03-2018 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Gene3D G3DSA:3.40.50.720 6356 6610 2.2E-56 T 29-03-2018 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Gene3D G3DSA:3.40.50.720 4814 5063 2.1E-54 T 29-03-2018 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Gene3D G3DSA:3.40.50.720 8133 8381 1.4E-45 T 29-03-2018 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 SMART SM01294 6647 6714 1.3E-7 T 29-03-2018 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 SMART SM01294 8436 8503 4.7E-8 T 29-03-2018 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 SMART SM01294 1761 1828 4.7E-6 T 29-03-2018 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 SMART SM01294 3248 3315 4.3E-8 T 29-03-2018 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 SMART SM01294 5105 5172 1.0E-5 T 29-03-2018 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Gene3D G3DSA:3.10.129.10 4248 4366 2.5E-4 T 29-03-2018 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Gene3D G3DSA:3.10.129.10 7639 7762 4.8E-5 T 29-03-2018 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Gene3D G3DSA:3.10.129.10 933 1040 1.1E-6 T 29-03-2018 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 SUPERFAMILY SSF51735 2745 2945 6.3E-45 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2959 3138 2.2E-62 T 29-03-2018 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8141 8321 3.2E-57 T 29-03-2018 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1475 1655 1.6E-62 T 29-03-2018 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6358 6537 4.3E-63 T 29-03-2018 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4822 5002 3.2E-58 T 29-03-2018 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 SUPERFAMILY SSF51735 4662 4807 5.51E-25 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 SUPERFAMILY SSF55048 2516 2577 7.06E-12 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 7122 7237 5.7E-13 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 5575 5692 7.2E-14 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 3719 3825 7.9E-16 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 413 532 1.3E-15 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2237 2357 2.1E-13 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Gene3D G3DSA:3.40.366.10 5905 6031 3.0E-27 T 29-03-2018 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Gene3D G3DSA:3.40.366.10 2569 2695 4.9E-27 T 29-03-2018 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Gene3D G3DSA:3.40.366.10 4047 4172 2.0E-26 T 29-03-2018 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 SUPERFAMILY SSF51735 6137 6340 1.11E-44 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 SUPERFAMILY SSF53901 32 408 1.41E-99 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 SUPERFAMILY SSF55048 7400 7461 5.62E-11 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Pfam PF00698 Acyl transferase domain 5728 6038 6.2E-54 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Pfam PF00698 Acyl transferase domain 3870 4184 5.5E-59 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Pfam PF00698 Acyl transferase domain 567 880 2.0E-57 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Pfam PF00698 Acyl transferase domain 2392 2704 4.4E-56 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Pfam PF00698 Acyl transferase domain 7276 7589 2.3E-57 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 SUPERFAMILY SSF55048 3994 4055 6.8E-12 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 2022 2038 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 SUPERFAMILY SSF51735 6358 6607 6.64E-50 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 SUPERFAMILY SSF47336 6641 6759 1.24E-24 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 SUPERFAMILY SSF51735 1393 1431 3.78E-27 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 SUPERFAMILY SSF51735 1202 1363 3.78E-27 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Gene3D G3DSA:3.40.366.10 564 701 6.9E-46 T 29-03-2018 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Gene3D G3DSA:3.40.366.10 3867 4002 1.4E-46 T 29-03-2018 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Gene3D G3DSA:3.40.366.10 5725 5860 7.3E-46 T 29-03-2018 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 Gene3D G3DSA:3.40.366.10 7273 7410 2.8E-47 T 29-03-2018 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 SUPERFAMILY SSF53901 3338 3714 5.16E-103 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 SUPERFAMILY SSF52151 5906 6017 2.01E-75 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS13790 c297eac8f99937fa8a02d045f5e65f79 8599 SUPERFAMILY SSF52151 5726 5847 2.01E-75 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS20345 400fd0df1db90fdd3b8867f8d384301a 365 Gene3D G3DSA:2.40.50.100 288 358 5.5E-19 T 29-03-2018 SMALA_RS20345 400fd0df1db90fdd3b8867f8d384301a 365 SUPERFAMILY SSF50331 253 363 1.17E-18 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal SMALA_RS20345 400fd0df1db90fdd3b8867f8d384301a 365 Pfam PF03459 TOBE domain 301 361 5.9E-14 T 29-03-2018 IPR005116 Transport-associated OB, type 1 SMALA_RS20345 400fd0df1db90fdd3b8867f8d384301a 365 SMART SM00382 39 228 1.4E-18 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS20345 400fd0df1db90fdd3b8867f8d384301a 365 Gene3D G3DSA:3.40.50.300 10 267 2.2E-63 T 29-03-2018 SMALA_RS20345 400fd0df1db90fdd3b8867f8d384301a 365 SUPERFAMILY SSF52540 26 253 2.3E-68 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS20345 400fd0df1db90fdd3b8867f8d384301a 365 Pfam PF00005 ABC transporter 33 178 5.9E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS20345 400fd0df1db90fdd3b8867f8d384301a 365 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS03025 2ac79b72338d240963a9f8dc89daa1f8 370 SUPERFAMILY SSF52096 21 205 1.84E-65 T 29-03-2018 IPR029045 ClpP/crotonase-like domain SMALA_RS03025 2ac79b72338d240963a9f8dc89daa1f8 370 SUPERFAMILY SSF52096 261 338 1.84E-65 T 29-03-2018 IPR029045 ClpP/crotonase-like domain SMALA_RS03025 2ac79b72338d240963a9f8dc89daa1f8 370 Gene3D G3DSA:3.90.226.10 2 346 8.7E-98 T 29-03-2018 SMALA_RS03025 2ac79b72338d240963a9f8dc89daa1f8 370 Pfam PF16113 Enoyl-CoA hydratase/isomerase 32 352 1.0E-125 T 29-03-2018 IPR032259 Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type GO:0003860 Reactome: R-HSA-70895 SMALA_RS15130 3a13d7094102e8af839dd744f1ece653 155 Pfam PF01037 Lrp/AsnC ligand binding domain 72 138 7.1E-13 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain SMALA_RS15130 3a13d7094102e8af839dd744f1ece653 155 Gene3D G3DSA:1.10.10.10 3 53 1.9E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS15130 3a13d7094102e8af839dd744f1ece653 155 Pfam PF13404 AsnC-type helix-turn-helix domain 3 44 3.2E-8 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMALA_RS15130 3a13d7094102e8af839dd744f1ece653 155 SUPERFAMILY SSF46785 3 63 8.06E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS15130 3a13d7094102e8af839dd744f1ece653 155 Gene3D G3DSA:3.30.70.920 56 149 3.0E-18 T 29-03-2018 SMALA_RS15130 3a13d7094102e8af839dd744f1ece653 155 SMART SM00344 3 109 7.9E-28 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 SMALA_RS15130 3a13d7094102e8af839dd744f1ece653 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 1.1E-9 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMALA_RS15130 3a13d7094102e8af839dd744f1ece653 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 30 1.1E-9 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMALA_RS15130 3a13d7094102e8af839dd744f1ece653 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 1.1E-9 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMALA_RS15130 3a13d7094102e8af839dd744f1ece653 155 SUPERFAMILY SSF54909 63 148 8.71E-17 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel SMALA_RS38940 c3fd9febfa941d84eb5238646cd586c7 1006 SUPERFAMILY SSF49785 681 808 1.46E-23 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS38940 c3fd9febfa941d84eb5238646cd586c7 1006 Pfam PF07691 PA14 domain 50 183 3.8E-20 T 29-03-2018 IPR011658 PA14 domain SMALA_RS38940 c3fd9febfa941d84eb5238646cd586c7 1006 Gene3D G3DSA:2.60.120.560 811 1006 3.1E-32 T 29-03-2018 SMALA_RS38940 c3fd9febfa941d84eb5238646cd586c7 1006 SUPERFAMILY SSF63829 240 537 1.44E-12 T 29-03-2018 SMALA_RS38940 c3fd9febfa941d84eb5238646cd586c7 1006 SUPERFAMILY SSF56988 96 214 1.57E-11 T 29-03-2018 SMALA_RS38940 c3fd9febfa941d84eb5238646cd586c7 1006 Gene3D G3DSA:2.120.10.30 317 593 1.2E-6 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like SMALA_RS38940 c3fd9febfa941d84eb5238646cd586c7 1006 SMART SM00758 49 189 1.1E-28 T 29-03-2018 IPR011658 PA14 domain SMALA_RS38940 c3fd9febfa941d84eb5238646cd586c7 1006 Gene3D G3DSA:3.90.182.10 36 288 6.3E-31 T 29-03-2018 SMALA_RS38940 c3fd9febfa941d84eb5238646cd586c7 1006 Pfam PF16990 Carbohydrate binding module (family 35) 682 809 3.5E-11 T 29-03-2018 IPR005084 Carbohydrate binding module family 6 GO:0030246 SMALA_RS38940 c3fd9febfa941d84eb5238646cd586c7 1006 Pfam PF06439 Domain of Unknown Function (DUF1080) 816 1003 1.1E-31 T 29-03-2018 IPR010496 Domain of unknown function DUF1080 SMALA_RS38940 c3fd9febfa941d84eb5238646cd586c7 1006 Gene3D G3DSA:2.60.120.260 662 809 3.2E-31 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS28520 5c0acabc3987fb206bac9a8f68958884 373 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 36 47 - T 29-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site SMALA_RS28520 5c0acabc3987fb206bac9a8f68958884 373 Pfam PF00082 Subtilase family 31 293 3.7E-48 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMALA_RS28520 5c0acabc3987fb206bac9a8f68958884 373 Gene3D G3DSA:3.40.50.200 1 310 5.5E-84 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMALA_RS28520 5c0acabc3987fb206bac9a8f68958884 373 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 87 97 - T 29-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site SMALA_RS28520 5c0acabc3987fb206bac9a8f68958884 373 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 244 254 - T 29-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site SMALA_RS28520 5c0acabc3987fb206bac9a8f68958884 373 PRINTS PR00723 Subtilisin serine protease family (S8) signature 31 50 5.1E-17 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related SMALA_RS28520 5c0acabc3987fb206bac9a8f68958884 373 PRINTS PR00723 Subtilisin serine protease family (S8) signature 243 259 5.1E-17 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related SMALA_RS28520 5c0acabc3987fb206bac9a8f68958884 373 PRINTS PR00723 Subtilisin serine protease family (S8) signature 83 96 5.1E-17 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related SMALA_RS28520 5c0acabc3987fb206bac9a8f68958884 373 SUPERFAMILY SSF52743 8 302 2.23E-78 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMALA_RS28520 5c0acabc3987fb206bac9a8f68958884 373 TIGRFAM TIGR03921 T7SS_mycosin: type VII secretion-associated serine protease mycosin 17 371 5.9E-95 T 29-03-2018 IPR023834 Type VII secretion system peptidase S8A, mycosin SMALA_RS00160 ced3afe2f56cfb8343a74eea747e6fa9 395 Gene3D G3DSA:3.40.50.1110 172 383 8.4E-25 T 29-03-2018 SMALA_RS00160 ced3afe2f56cfb8343a74eea747e6fa9 395 SUPERFAMILY SSF52266 172 381 3.54E-26 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain SMALA_RS00160 ced3afe2f56cfb8343a74eea747e6fa9 395 Pfam PF14606 GDSL-like Lipase/Acylhydrolase family 178 277 4.7E-14 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain SMALA_RS38195 5ae9e1887e5d50575f2ac021b74129e5 494 TIGRFAM TIGR00838 argH: argininosuccinate lyase 38 409 4.2E-91 T 29-03-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SMALA_RS38195 5ae9e1887e5d50575f2ac021b74129e5 494 PRINTS PR00145 Argininosuccinate lyase family signature 277 293 2.9E-29 T 29-03-2018 SMALA_RS38195 5ae9e1887e5d50575f2ac021b74129e5 494 PRINTS PR00145 Argininosuccinate lyase family signature 195 211 2.9E-29 T 29-03-2018 SMALA_RS38195 5ae9e1887e5d50575f2ac021b74129e5 494 PRINTS PR00145 Argininosuccinate lyase family signature 144 164 2.9E-29 T 29-03-2018 SMALA_RS38195 5ae9e1887e5d50575f2ac021b74129e5 494 PRINTS PR00145 Argininosuccinate lyase family signature 233 257 2.9E-29 T 29-03-2018 SMALA_RS38195 5ae9e1887e5d50575f2ac021b74129e5 494 PRINTS PR00145 Argininosuccinate lyase family signature 103 125 2.9E-29 T 29-03-2018 SMALA_RS38195 5ae9e1887e5d50575f2ac021b74129e5 494 ProSitePatterns PS00163 Fumarate lyases signature. 277 286 - T 29-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 SMALA_RS38195 5ae9e1887e5d50575f2ac021b74129e5 494 Gene3D G3DSA:1.10.40.30 378 432 4.4E-13 T 29-03-2018 SMALA_RS38195 5ae9e1887e5d50575f2ac021b74129e5 494 Pfam PF00206 Lyase 98 302 5.1E-43 T 29-03-2018 IPR022761 Fumarate lyase, N-terminal SMALA_RS38195 5ae9e1887e5d50575f2ac021b74129e5 494 Gene3D G3DSA:1.10.275.10 32 108 1.8E-8 T 29-03-2018 IPR024083 Fumarase/histidase, N-terminal SMALA_RS38195 5ae9e1887e5d50575f2ac021b74129e5 494 Pfam PF14698 Argininosuccinate lyase C-terminal 366 410 8.4E-13 T 29-03-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SMALA_RS38195 5ae9e1887e5d50575f2ac021b74129e5 494 PRINTS PR00149 Fumarate lyase superfamily signature 104 122 6.9E-21 T 29-03-2018 IPR000362 Fumarate lyase family SMALA_RS38195 5ae9e1887e5d50575f2ac021b74129e5 494 PRINTS PR00149 Fumarate lyase superfamily signature 149 167 6.9E-21 T 29-03-2018 IPR000362 Fumarate lyase family SMALA_RS38195 5ae9e1887e5d50575f2ac021b74129e5 494 PRINTS PR00149 Fumarate lyase superfamily signature 233 260 6.9E-21 T 29-03-2018 IPR000362 Fumarate lyase family SMALA_RS38195 5ae9e1887e5d50575f2ac021b74129e5 494 PRINTS PR00149 Fumarate lyase superfamily signature 277 293 6.9E-21 T 29-03-2018 IPR000362 Fumarate lyase family SMALA_RS38195 5ae9e1887e5d50575f2ac021b74129e5 494 Gene3D G3DSA:1.20.200.10 109 377 1.8E-67 T 29-03-2018 SMALA_RS38195 5ae9e1887e5d50575f2ac021b74129e5 494 SUPERFAMILY SSF48557 37 403 9.9E-90 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 SMALA_RS37325 0989d38efe8dbf95325cbf544b5fcf79 282 Gene3D G3DSA:3.40.1080.10 1 243 3.0E-59 T 29-03-2018 SMALA_RS37325 0989d38efe8dbf95325cbf544b5fcf79 282 SUPERFAMILY SSF100950 1 265 4.08E-67 T 29-03-2018 SMALA_RS37325 0989d38efe8dbf95325cbf544b5fcf79 282 Pfam PF01144 Coenzyme A transferase 1 199 3.9E-33 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 SMALA_RS37325 0989d38efe8dbf95325cbf544b5fcf79 282 SMART SM00882 1 222 1.2E-23 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 SMALA_RS24155 c7a7a87bad430b1b2b01d2ea6c713659 169 Pfam PF00741 Gas vesicle protein 18 56 5.0E-12 T 29-03-2018 IPR000638 Gas vesicle protein GvpA GO:0005198|GO:0012506 SMALA_RS24155 c7a7a87bad430b1b2b01d2ea6c713659 169 Hamap MF_00576 Gas vesicle structural protein [gvpA]. 7 108 27.23 T 29-03-2018 IPR000638 Gas vesicle protein GvpA GO:0005198|GO:0012506 SMALA_RS24155 c7a7a87bad430b1b2b01d2ea6c713659 169 ProSitePatterns PS00669 Gas vesicles protein GVPa signature 2. 52 65 - T 29-03-2018 IPR018493 Gas vesicle protein GvpA, conserved site GO:0005198|GO:0012506 SMALA_RS26675 f3039dbb9fa68a6708893e3bb341c013 793 SUPERFAMILY SSF49452 619 703 8.44E-14 T 29-03-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 SMALA_RS26675 f3039dbb9fa68a6708893e3bb341c013 793 Gene3D G3DSA:2.60.40.1120 624 708 1.7E-16 T 29-03-2018 SMALA_RS26675 f3039dbb9fa68a6708893e3bb341c013 793 Gene3D G3DSA:2.60.40.1120 709 793 1.7E-12 T 29-03-2018 SMALA_RS26675 f3039dbb9fa68a6708893e3bb341c013 793 SUPERFAMILY SSF103473 19 206 1.14E-56 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS26675 f3039dbb9fa68a6708893e3bb341c013 793 SUPERFAMILY SSF103473 252 469 1.14E-56 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS26675 f3039dbb9fa68a6708893e3bb341c013 793 SUPERFAMILY SSF49464 542 619 6.15E-10 T 29-03-2018 IPR008969 Carboxypeptidase-like, regulatory domain SMALA_RS26675 f3039dbb9fa68a6708893e3bb341c013 793 SUPERFAMILY SSF49464 709 776 1.53E-10 T 29-03-2018 IPR008969 Carboxypeptidase-like, regulatory domain SMALA_RS26675 f3039dbb9fa68a6708893e3bb341c013 793 Pfam PF07690 Major Facilitator Superfamily 22 414 3.1E-38 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS26675 f3039dbb9fa68a6708893e3bb341c013 793 Gene3D G3DSA:1.20.1250.20 262 477 1.4E-24 T 29-03-2018 SMALA_RS26675 f3039dbb9fa68a6708893e3bb341c013 793 Gene3D G3DSA:1.20.1250.20 17 204 4.0E-29 T 29-03-2018 SMALA_RS26675 f3039dbb9fa68a6708893e3bb341c013 793 Gene3D G3DSA:2.60.40.1120 536 613 9.1E-9 T 29-03-2018 SMALA_RS26675 f3039dbb9fa68a6708893e3bb341c013 793 Pfam PF13620 Carboxypeptidase regulatory-like domain 709 775 1.0E-11 T 29-03-2018 SMALA_RS26675 f3039dbb9fa68a6708893e3bb341c013 793 Pfam PF13620 Carboxypeptidase regulatory-like domain 625 703 1.5E-15 T 29-03-2018 SMALA_RS26675 f3039dbb9fa68a6708893e3bb341c013 793 Pfam PF13620 Carboxypeptidase regulatory-like domain 542 608 8.0E-9 T 29-03-2018 SMALA_RS10405 eca22c6f635b113bc1de6abba98d6799 342 ProSitePatterns PS00433 Phosphofructokinase signature. 266 284 - T 29-03-2018 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMALA_RS10405 eca22c6f635b113bc1de6abba98d6799 342 Pfam PF00365 Phosphofructokinase 2 297 5.3E-105 T 29-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMALA_RS10405 eca22c6f635b113bc1de6abba98d6799 342 Gene3D G3DSA:3.40.50.450 1 198 4.1E-78 T 29-03-2018 SMALA_RS10405 eca22c6f635b113bc1de6abba98d6799 342 TIGRFAM TIGR02483 PFK_mixed: phosphofructokinase 2 322 1.0E-155 T 29-03-2018 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 SMALA_RS10405 eca22c6f635b113bc1de6abba98d6799 342 Gene3D G3DSA:3.40.50.450 199 323 3.4E-16 T 29-03-2018 SMALA_RS10405 eca22c6f635b113bc1de6abba98d6799 342 SUPERFAMILY SSF53784 1 337 1.27E-123 T 29-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMALA_RS10405 eca22c6f635b113bc1de6abba98d6799 342 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 159 175 5.8E-72 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMALA_RS10405 eca22c6f635b113bc1de6abba98d6799 342 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 262 284 5.8E-72 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMALA_RS10405 eca22c6f635b113bc1de6abba98d6799 342 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 212 224 5.8E-72 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMALA_RS10405 eca22c6f635b113bc1de6abba98d6799 342 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 93 109 5.8E-72 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMALA_RS10405 eca22c6f635b113bc1de6abba98d6799 342 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 177 194 5.8E-72 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMALA_RS10405 eca22c6f635b113bc1de6abba98d6799 342 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 139 157 5.8E-72 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMALA_RS10405 eca22c6f635b113bc1de6abba98d6799 342 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 5 24 5.8E-72 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMALA_RS10405 eca22c6f635b113bc1de6abba98d6799 342 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 31 44 5.8E-72 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMALA_RS10405 eca22c6f635b113bc1de6abba98d6799 342 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 121 138 5.8E-72 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMALA_RS10405 eca22c6f635b113bc1de6abba98d6799 342 Hamap MF_01976 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase [pfp]. 1 342 43.805 T 29-03-2018 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 SMALA_RS10405 eca22c6f635b113bc1de6abba98d6799 342 PIRSF PIRSF000532 1 340 8.4E-127 T 29-03-2018 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 SMALA_RS18570 dc3f8c39a5d10be855c2ab6ab0d8a7a8 278 SUPERFAMILY SSF56784 11 228 2.86E-32 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS18570 dc3f8c39a5d10be855c2ab6ab0d8a7a8 278 Pfam PF12710 haloacid dehalogenase-like hydrolase 15 200 4.3E-32 T 29-03-2018 SMALA_RS18570 dc3f8c39a5d10be855c2ab6ab0d8a7a8 278 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 14 213 2.5E-61 T 29-03-2018 IPR006385 HAD-superfamily hydrolase, subfamily IB, SerB1-like SMALA_RS18570 dc3f8c39a5d10be855c2ab6ab0d8a7a8 278 Gene3D G3DSA:3.40.50.1000 12 235 3.5E-20 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS18570 dc3f8c39a5d10be855c2ab6ab0d8a7a8 278 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 14 202 3.9E-22 T 29-03-2018 SMALA_RS13795 0d1c47805d2f99381dd9154946e9f5c4 3459 SUPERFAMILY SSF52151 754 862 4.97E-76 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS13795 0d1c47805d2f99381dd9154946e9f5c4 3459 SUPERFAMILY SSF52151 574 695 4.97E-76 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS13795 0d1c47805d2f99381dd9154946e9f5c4 3459 SUPERFAMILY SSF55048 700 761 1.7E-11 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS13795 0d1c47805d2f99381dd9154946e9f5c4 3459 SUPERFAMILY SSF51735 1216 1285 5.9E-27 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS13795 0d1c47805d2f99381dd9154946e9f5c4 3459 SUPERFAMILY SSF51735 1331 1440 5.9E-27 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS13795 0d1c47805d2f99381dd9154946e9f5c4 3459 Pfam PF00550 Phosphopantetheine attachment site 3293 3359 3.7E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS13795 0d1c47805d2f99381dd9154946e9f5c4 3459 Pfam PF00550 Phosphopantetheine attachment site 1741 1807 2.5E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS13795 0d1c47805d2f99381dd9154946e9f5c4 3459 Gene3D G3DSA:1.10.1200.10 1722 1817 2.3E-19 T 29-03-2018 SMALA_RS13795 0d1c47805d2f99381dd9154946e9f5c4 3459 Gene3D G3DSA:3.40.47.10 301 462 2.7E-61 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13795 0d1c47805d2f99381dd9154946e9f5c4 3459 Gene3D G3DSA:3.40.47.10 2097 2258 7.5E-65 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13795 0d1c47805d2f99381dd9154946e9f5c4 3459 Gene3D G3DSA:3.40.366.10 748 874 5.2E-31 T 29-03-2018 SMALA_RS13795 0d1c47805d2f99381dd9154946e9f5c4 3459 Gene3D G3DSA:3.40.366.10 2538 2665 2.6E-31 T 29-03-2018 SMALA_RS13795 0d1c47805d2f99381dd9154946e9f5c4 3459 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1766 1781 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS13795 0d1c47805d2f99381dd9154946e9f5c4 3459 Gene3D G3DSA:3.40.50.720 2992 3254 1.9E-52 T 29-03-2018 SMALA_RS13795 0d1c47805d2f99381dd9154946e9f5c4 3459 Gene3D G3DSA:3.40.50.720 1447 1707 3.8E-53 T 29-03-2018 SMALA_RS13795 0d1c47805d2f99381dd9154946e9f5c4 3459 Gene3D G3DSA:3.10.129.10 940 1060 2.6E-7 T 29-03-2018 SMALA_RS13795 0d1c47805d2f99381dd9154946e9f5c4 3459 Pfam PF08659 KR domain 3000 3180 5.3E-55 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13795 0d1c47805d2f99381dd9154946e9f5c4 3459 Pfam PF08659 KR domain 1455 1633 1.0E-59 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13795 0d1c47805d2f99381dd9154946e9f5c4 3459 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1995 2011 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS13795 0d1c47805d2f99381dd9154946e9f5c4 3459 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1832 2082 2.5E-89 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS13795 0d1c47805d2f99381dd9154946e9f5c4 3459 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 36 286 9.2E-89 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS13795 0d1c47805d2f99381dd9154946e9f5c4 3459 SMART SM01294 1740 1807 1.5E-6 T 29-03-2018 SMALA_RS13795 0d1c47805d2f99381dd9154946e9f5c4 3459 SMART SM01294 3292 3359 1.3E-8 T 29-03-2018 SMALA_RS13795 0d1c47805d2f99381dd9154946e9f5c4 3459 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2210 2328 2.4E-15 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13795 0d1c47805d2f99381dd9154946e9f5c4 3459 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 414 540 8.8E-14 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13795 0d1c47805d2f99381dd9154946e9f5c4 3459 Gene3D G3DSA:3.40.50.10090 2800 2938 0.11 T 29-03-2018 SMALA_RS13795 0d1c47805d2f99381dd9154946e9f5c4 3459 SMART SM00823 Phosphopantetheine attachment site 3291 3363 6.1E-32 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13795 0d1c47805d2f99381dd9154946e9f5c4 3459 SMART SM00823 Phosphopantetheine attachment site 1739 1811 1.0E-32 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13795 0d1c47805d2f99381dd9154946e9f5c4 3459 Gene3D G3DSA:1.10.1200.10 3263 3368 5.6E-20 T 29-03-2018 SMALA_RS13795 0d1c47805d2f99381dd9154946e9f5c4 3459 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 294 411 1.8E-43 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS13795 0d1c47805d2f99381dd9154946e9f5c4 3459 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2090 2207 1.7E-44 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS13795 0d1c47805d2f99381dd9154946e9f5c4 3459 SUPERFAMILY SSF55048 2490 2551 9.94E-12 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS13795 0d1c47805d2f99381dd9154946e9f5c4 3459 SUPERFAMILY SSF52151 2544 2650 4.71E-77 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS13795 0d1c47805d2f99381dd9154946e9f5c4 3459 SUPERFAMILY SSF52151 2364 2485 4.71E-77 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS13795 0d1c47805d2f99381dd9154946e9f5c4 3459 SUPERFAMILY SSF47336 3284 3368 2.62E-22 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS13795 0d1c47805d2f99381dd9154946e9f5c4 3459 Gene3D G3DSA:3.40.366.10 2363 2498 2.3E-46 T 29-03-2018 SMALA_RS13795 0d1c47805d2f99381dd9154946e9f5c4 3459 Gene3D G3DSA:3.40.366.10 573 708 5.7E-47 T 29-03-2018 SMALA_RS13795 0d1c47805d2f99381dd9154946e9f5c4 3459 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3318 3333 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS13795 0d1c47805d2f99381dd9154946e9f5c4 3459 SUPERFAMILY SSF53901 1828 2205 3.28E-105 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13795 0d1c47805d2f99381dd9154946e9f5c4 3459 Pfam PF08990 Erythronolide synthase docking 4 29 8.0E-9 T 29-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 SMALA_RS13795 0d1c47805d2f99381dd9154946e9f5c4 3459 Pfam PF14765 Polyketide synthase dehydratase 937 1209 6.1E-58 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13795 0d1c47805d2f99381dd9154946e9f5c4 3459 Pfam PF00698 Acyl transferase domain 2366 2679 4.4E-54 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS13795 0d1c47805d2f99381dd9154946e9f5c4 3459 Pfam PF00698 Acyl transferase domain 576 888 1.6E-57 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS13795 0d1c47805d2f99381dd9154946e9f5c4 3459 SUPERFAMILY SSF53901 32 410 1.04E-102 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13795 0d1c47805d2f99381dd9154946e9f5c4 3459 SUPERFAMILY SSF51735 2995 3244 1.49E-45 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS13795 0d1c47805d2f99381dd9154946e9f5c4 3459 SUPERFAMILY SSF47336 1736 1847 8.11E-24 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS13795 0d1c47805d2f99381dd9154946e9f5c4 3459 Gene3D G3DSA:3.40.47.10 28 298 2.5E-84 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13795 0d1c47805d2f99381dd9154946e9f5c4 3459 Gene3D G3DSA:3.40.47.10 1825 2094 9.7E-86 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13795 0d1c47805d2f99381dd9154946e9f5c4 3459 Gene3D G3DSA:3.30.70.250 709 747 4.2E-17 T 29-03-2018 SMALA_RS13795 0d1c47805d2f99381dd9154946e9f5c4 3459 Gene3D G3DSA:3.30.70.250 2499 2537 8.7E-18 T 29-03-2018 SMALA_RS13795 0d1c47805d2f99381dd9154946e9f5c4 3459 SMART SM00825 Beta-ketoacyl synthase 1834 2260 5.3E-224 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS13795 0d1c47805d2f99381dd9154946e9f5c4 3459 SMART SM00825 Beta-ketoacyl synthase 38 464 1.8E-219 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS13795 0d1c47805d2f99381dd9154946e9f5c4 3459 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 577 869 1.5E-128 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS13795 0d1c47805d2f99381dd9154946e9f5c4 3459 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2367 2660 8.5E-128 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS13795 0d1c47805d2f99381dd9154946e9f5c4 3459 SUPERFAMILY SSF51735 2772 2985 1.23E-47 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS13795 0d1c47805d2f99381dd9154946e9f5c4 3459 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3000 3181 6.7E-49 T 29-03-2018 SMALA_RS13795 0d1c47805d2f99381dd9154946e9f5c4 3459 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1455 1635 1.9E-61 T 29-03-2018 SMALA_RS13795 0d1c47805d2f99381dd9154946e9f5c4 3459 SMART SM00826 937 1100 4.9E-84 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13795 0d1c47805d2f99381dd9154946e9f5c4 3459 SUPERFAMILY SSF51735 1455 1675 5.27E-49 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS13795 0d1c47805d2f99381dd9154946e9f5c4 3459 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 199 215 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS29465 92a0a4fdcfe1c7bff909fc55d2d6406b 2161 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 35 446 1.0E-132 T 29-03-2018 IPR010071 Amino acid adenylation domain SMALA_RS29465 92a0a4fdcfe1c7bff909fc55d2d6406b 2161 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1102 1503 4.9E-135 T 29-03-2018 IPR010071 Amino acid adenylation domain SMALA_RS29465 92a0a4fdcfe1c7bff909fc55d2d6406b 2161 ProSitePatterns PS00012 Phosphopantetheine attachment site. 554 569 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS29465 92a0a4fdcfe1c7bff909fc55d2d6406b 2161 Gene3D G3DSA:3.40.50.980 1237 1382 1.6E-33 T 29-03-2018 SMALA_RS29465 92a0a4fdcfe1c7bff909fc55d2d6406b 2161 SUPERFAMILY SSF52777 1867 2130 1.33E-31 T 29-03-2018 SMALA_RS29465 92a0a4fdcfe1c7bff909fc55d2d6406b 2161 Gene3D G3DSA:3.40.50.980 159 320 4.8E-42 T 29-03-2018 SMALA_RS29465 92a0a4fdcfe1c7bff909fc55d2d6406b 2161 SUPERFAMILY SSF47336 1581 1650 1.13E-16 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS29465 92a0a4fdcfe1c7bff909fc55d2d6406b 2161 SUPERFAMILY SSF52777 616 786 4.45E-50 T 29-03-2018 SMALA_RS29465 92a0a4fdcfe1c7bff909fc55d2d6406b 2161 ProSitePatterns PS00455 Putative AMP-binding domain signature. 157 168 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS29465 92a0a4fdcfe1c7bff909fc55d2d6406b 2161 Gene3D G3DSA:3.30.559.10 1659 1862 7.6E-26 T 29-03-2018 SMALA_RS29465 92a0a4fdcfe1c7bff909fc55d2d6406b 2161 Gene3D G3DSA:1.10.1200.10 536 595 1.5E-24 T 29-03-2018 SMALA_RS29465 92a0a4fdcfe1c7bff909fc55d2d6406b 2161 SUPERFAMILY SSF52777 1672 1848 1.02E-27 T 29-03-2018 SMALA_RS29465 92a0a4fdcfe1c7bff909fc55d2d6406b 2161 Pfam PF00668 Condensation domain 613 1061 7.0E-93 T 29-03-2018 IPR001242 Condensation domain SMALA_RS29465 92a0a4fdcfe1c7bff909fc55d2d6406b 2161 Pfam PF00668 Condensation domain 1690 2042 7.7E-40 T 29-03-2018 IPR001242 Condensation domain SMALA_RS29465 92a0a4fdcfe1c7bff909fc55d2d6406b 2161 Pfam PF13193 AMP-binding enzyme C-terminal domain 1487 1563 3.0E-15 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS29465 92a0a4fdcfe1c7bff909fc55d2d6406b 2161 Pfam PF13193 AMP-binding enzyme C-terminal domain 430 505 7.3E-13 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS29465 92a0a4fdcfe1c7bff909fc55d2d6406b 2161 Gene3D G3DSA:3.30.300.30 417 535 3.2E-37 T 29-03-2018 SMALA_RS29465 92a0a4fdcfe1c7bff909fc55d2d6406b 2161 Gene3D G3DSA:3.30.300.30 1474 1592 7.2E-41 T 29-03-2018 SMALA_RS29465 92a0a4fdcfe1c7bff909fc55d2d6406b 2161 SMART SM00823 Phosphopantetheine attachment site 530 599 1.5E-7 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS29465 92a0a4fdcfe1c7bff909fc55d2d6406b 2161 SMART SM00823 Phosphopantetheine attachment site 1588 1656 4.5E-7 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS29465 92a0a4fdcfe1c7bff909fc55d2d6406b 2161 SUPERFAMILY SSF52777 799 1065 3.0E-62 T 29-03-2018 SMALA_RS29465 92a0a4fdcfe1c7bff909fc55d2d6406b 2161 Pfam PF00550 Phosphopantetheine attachment site 533 595 1.4E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS29465 92a0a4fdcfe1c7bff909fc55d2d6406b 2161 Pfam PF00550 Phosphopantetheine attachment site 1590 1650 1.2E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS29465 92a0a4fdcfe1c7bff909fc55d2d6406b 2161 Gene3D G3DSA:3.40.50.980 1073 1236 5.1E-49 T 29-03-2018 SMALA_RS29465 92a0a4fdcfe1c7bff909fc55d2d6406b 2161 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1231 1242 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS29465 92a0a4fdcfe1c7bff909fc55d2d6406b 2161 Gene3D G3DSA:3.40.50.980 7 158 8.3E-46 T 29-03-2018 SMALA_RS29465 92a0a4fdcfe1c7bff909fc55d2d6406b 2161 Gene3D G3DSA:3.30.559.10 596 811 3.9E-45 T 29-03-2018 SMALA_RS29465 92a0a4fdcfe1c7bff909fc55d2d6406b 2161 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1612 1627 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS29465 92a0a4fdcfe1c7bff909fc55d2d6406b 2161 Gene3D G3DSA:1.10.1200.10 1593 1658 9.2E-23 T 29-03-2018 SMALA_RS29465 92a0a4fdcfe1c7bff909fc55d2d6406b 2161 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 1994 2153 2.1E-38 T 29-03-2018 IPR010060 Non-ribosomal peptide synthase SMALA_RS29465 92a0a4fdcfe1c7bff909fc55d2d6406b 2161 Pfam PF00501 AMP-binding enzyme 14 422 3.5E-100 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS29465 92a0a4fdcfe1c7bff909fc55d2d6406b 2161 Pfam PF00501 AMP-binding enzyme 1082 1479 2.7E-97 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS29465 92a0a4fdcfe1c7bff909fc55d2d6406b 2161 SUPERFAMILY SSF56801 6 542 3.66E-160 T 29-03-2018 SMALA_RS29465 92a0a4fdcfe1c7bff909fc55d2d6406b 2161 SUPERFAMILY SSF47336 523 595 6.28E-20 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS29465 92a0a4fdcfe1c7bff909fc55d2d6406b 2161 Gene3D G3DSA:2.30.38.10 1391 1472 1.9E-24 T 29-03-2018 SMALA_RS29465 92a0a4fdcfe1c7bff909fc55d2d6406b 2161 Gene3D G3DSA:2.30.38.10 334 415 2.0E-23 T 29-03-2018 SMALA_RS29465 92a0a4fdcfe1c7bff909fc55d2d6406b 2161 SUPERFAMILY SSF56801 1040 1600 1.7E-157 T 29-03-2018 SMALA_RS09325 2c35c51c69921e099251f01825379934 299 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 290 1.1E-15 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS09325 2c35c51c69921e099251f01825379934 299 SUPERFAMILY SSF161098 34 299 6.07E-65 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS09325 2c35c51c69921e099251f01825379934 299 Gene3D G3DSA:1.10.3720.10 25 286 2.8E-39 T 29-03-2018 SMALA_RS16095 a25ca764ee354569c0810bc867f80e44 225 SUPERFAMILY SSF161098 22 205 6.41E-33 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS16095 a25ca764ee354569c0810bc867f80e44 225 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 47 215 3.7E-18 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS16095 a25ca764ee354569c0810bc867f80e44 225 Gene3D G3DSA:1.10.3720.10 18 217 4.8E-27 T 29-03-2018 SMALA_RS13365 506dfa320cff7c1e308d3c161ce06873 341 ProSitePatterns PS01103 Aspartate-semialdehyde dehydrogenase signature. 240 254 - T 29-03-2018 IPR000319 Aspartate-semialdehyde dehydrogenase, conserved site GO:0004073|GO:0006520|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 SMALA_RS13365 506dfa320cff7c1e308d3c161ce06873 341 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 2 113 8.3E-30 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 SMALA_RS13365 506dfa320cff7c1e308d3c161ce06873 341 SUPERFAMILY SSF55347 126 324 1.58E-59 T 29-03-2018 SMALA_RS13365 506dfa320cff7c1e308d3c161ce06873 341 PIRSF PIRSF000148 1 341 2.3E-106 T 29-03-2018 SMALA_RS13365 506dfa320cff7c1e308d3c161ce06873 341 SMART SM00859 2 117 2.6E-37 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 SMALA_RS13365 506dfa320cff7c1e308d3c161ce06873 341 Gene3D G3DSA:3.30.360.10 138 320 5.5E-66 T 29-03-2018 SMALA_RS13365 506dfa320cff7c1e308d3c161ce06873 341 SUPERFAMILY SSF51735 1 153 5.79E-44 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS13365 506dfa320cff7c1e308d3c161ce06873 341 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 1 337 33.121 T 29-03-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 SMALA_RS13365 506dfa320cff7c1e308d3c161ce06873 341 Gene3D G3DSA:3.40.50.720 1 137 5.0E-37 T 29-03-2018 SMALA_RS13365 506dfa320cff7c1e308d3c161ce06873 341 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 2 337 2.2E-126 T 29-03-2018 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 SMALA_RS13365 506dfa320cff7c1e308d3c161ce06873 341 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 136 323 3.9E-52 T 29-03-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 SMALA_RS30375 e8aa6a5bfb2a37dafe1b4c8a5681119f 580 SUPERFAMILY SSF52467 183 346 9.82E-40 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain SMALA_RS30375 e8aa6a5bfb2a37dafe1b4c8a5681119f 580 SUPERFAMILY SSF52518 1 175 2.23E-39 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold SMALA_RS30375 e8aa6a5bfb2a37dafe1b4c8a5681119f 580 Gene3D G3DSA:3.40.50.970 334 536 3.4E-39 T 29-03-2018 SMALA_RS30375 e8aa6a5bfb2a37dafe1b4c8a5681119f 580 Gene3D G3DSA:3.40.50.1220 187 333 2.7E-31 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain SMALA_RS30375 e8aa6a5bfb2a37dafe1b4c8a5681119f 580 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 5 171 2.3E-40 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 SMALA_RS30375 e8aa6a5bfb2a37dafe1b4c8a5681119f 580 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 192 318 2.1E-28 T 29-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 SMALA_RS30375 e8aa6a5bfb2a37dafe1b4c8a5681119f 580 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 383 529 2.9E-38 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 SMALA_RS30375 e8aa6a5bfb2a37dafe1b4c8a5681119f 580 Gene3D G3DSA:3.40.50.970 1 186 3.2E-41 T 29-03-2018 SMALA_RS30375 e8aa6a5bfb2a37dafe1b4c8a5681119f 580 SUPERFAMILY SSF52518 360 545 3.54E-56 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold SMALA_RS03475 0362de95b598372f7a6159a2981d48c8 197 SUPERFAMILY SSF52540 17 191 3.8E-21 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS03475 0362de95b598372f7a6159a2981d48c8 197 Pfam PF03029 Conserved hypothetical ATP binding protein 23 190 5.2E-26 T 29-03-2018 IPR004130 GPN-loop GTPase SMALA_RS03475 0362de95b598372f7a6159a2981d48c8 197 Gene3D G3DSA:3.40.50.300 14 194 7.3E-18 T 29-03-2018 SMALA_RS40770 b26a74927fa1631204bf3e175901f775 226 SMART SM00895 89 212 5.2E-16 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS40770 b26a74927fa1631204bf3e175901f775 226 Gene3D G3DSA:1.20.120.530 77 226 1.5E-30 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS40770 b26a74927fa1631204bf3e175901f775 226 Pfam PF07729 FCD domain 90 211 1.6E-23 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS40770 b26a74927fa1631204bf3e175901f775 226 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 54 70 1.8E-5 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS40770 b26a74927fa1631204bf3e175901f775 226 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 54 1.8E-5 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS40770 b26a74927fa1631204bf3e175901f775 226 SMART SM00345 22 78 2.1E-8 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS40770 b26a74927fa1631204bf3e175901f775 226 Pfam PF00392 Bacterial regulatory proteins, gntR family 23 75 1.1E-13 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS40770 b26a74927fa1631204bf3e175901f775 226 SUPERFAMILY SSF46785 22 83 3.13E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS40770 b26a74927fa1631204bf3e175901f775 226 SUPERFAMILY SSF48008 84 217 1.02E-23 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS40770 b26a74927fa1631204bf3e175901f775 226 Gene3D G3DSA:1.10.10.10 4 76 8.9E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS02340 0fa32b1d7f454afd8850e6e3d23f2946 251 SUPERFAMILY SSF54001 2 248 1.28E-62 T 29-03-2018 SMALA_RS02340 0fa32b1d7f454afd8850e6e3d23f2946 251 Gene3D G3DSA:3.30.2140.10 1 130 4.6E-29 T 29-03-2018 SMALA_RS02340 0fa32b1d7f454afd8850e6e3d23f2946 251 Gene3D G3DSA:3.30.2140.10 131 250 1.2E-4 T 29-03-2018 SMALA_RS02340 0fa32b1d7f454afd8850e6e3d23f2946 251 Pfam PF00797 N-acetyltransferase 20 246 2.7E-39 T 29-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 SMALA_RS38380 96b5b273ae2a7e9bc47f950693a48ffa 167 PRINTS PR00598 Bacterial regulatory protein MarR family signature 124 144 1.1E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS38380 96b5b273ae2a7e9bc47f950693a48ffa 167 PRINTS PR00598 Bacterial regulatory protein MarR family signature 75 90 1.1E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS38380 96b5b273ae2a7e9bc47f950693a48ffa 167 PRINTS PR00598 Bacterial regulatory protein MarR family signature 94 110 1.1E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS38380 96b5b273ae2a7e9bc47f950693a48ffa 167 SMART SM00347 34 134 6.4E-21 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS38380 96b5b273ae2a7e9bc47f950693a48ffa 167 Pfam PF01047 MarR family 45 99 4.8E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS38380 96b5b273ae2a7e9bc47f950693a48ffa 167 SUPERFAMILY SSF46785 27 143 2.54E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS38380 96b5b273ae2a7e9bc47f950693a48ffa 167 Gene3D G3DSA:1.10.10.10 14 118 3.8E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS38380 96b5b273ae2a7e9bc47f950693a48ffa 167 Gene3D G3DSA:1.10.287.100 119 153 1.6E-9 T 29-03-2018 SMALA_RS17865 bc36a44c732b8538515188ab219ba523 250 SMART SM00382 26 223 3.4E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS17865 bc36a44c732b8538515188ab219ba523 250 SUPERFAMILY SSF52540 2 245 3.42E-80 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS17865 bc36a44c732b8538515188ab219ba523 250 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS17865 bc36a44c732b8538515188ab219ba523 250 PIRSF PIRSF039085 1 250 2.9E-119 T 29-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 SMALA_RS17865 bc36a44c732b8538515188ab219ba523 250 Pfam PF00005 ABC transporter 17 175 2.8E-35 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS17865 bc36a44c732b8538515188ab219ba523 250 Gene3D G3DSA:3.40.50.300 1 249 4.0E-74 T 29-03-2018 SMALA_RS04050 8482579aecec5c6328b16d942d426919 431 SUPERFAMILY SSF51621 99 347 3.35E-13 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SMALA_RS04050 8482579aecec5c6328b16d942d426919 431 Gene3D G3DSA:3.20.20.360 79 378 1.1E-42 T 29-03-2018 SMALA_RS04050 8482579aecec5c6328b16d942d426919 431 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 114 298 1.1E-6 T 29-03-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 SMALA_RS22790 7d65d6ed328018af549899dedb6ea633 501 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 236 501 20.609 T 29-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 SMALA_RS22790 7d65d6ed328018af549899dedb6ea633 501 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 236 496 8.5E-48 T 29-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 SMALA_RS22790 7d65d6ed328018af549899dedb6ea633 501 PIRSF PIRSF017184 1 487 1.3E-106 T 29-03-2018 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 SMALA_RS22790 7d65d6ed328018af549899dedb6ea633 501 SUPERFAMILY SSF53613 236 497 2.65E-60 T 29-03-2018 IPR029056 Ribokinase-like SMALA_RS22790 7d65d6ed328018af549899dedb6ea633 501 Pfam PF01256 Carbohydrate kinase 259 491 2.6E-53 T 29-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 SMALA_RS22790 7d65d6ed328018af549899dedb6ea633 501 Gene3D G3DSA:3.40.50.10260 1 229 9.2E-55 T 29-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 SMALA_RS22790 7d65d6ed328018af549899dedb6ea633 501 Gene3D G3DSA:3.40.1190.20 233 501 7.6E-52 T 29-03-2018 IPR029056 Ribokinase-like SMALA_RS22790 7d65d6ed328018af549899dedb6ea633 501 SUPERFAMILY SSF64153 4 257 1.28E-45 T 29-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 SMALA_RS22790 7d65d6ed328018af549899dedb6ea633 501 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 2 223 20.201 T 29-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 SMALA_RS22790 7d65d6ed328018af549899dedb6ea633 501 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 437 447 - T 29-03-2018 IPR017953 Carbohydrate kinase, predicted, conserved site SMALA_RS22790 7d65d6ed328018af549899dedb6ea633 501 Pfam PF03853 YjeF-related protein N-terminus 25 202 2.9E-35 T 29-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 SMALA_RS05590 342d98e9a5707c6ff327a754c722827a 278 Gene3D G3DSA:1.20.1250.20 2 278 1.3E-4 T 29-03-2018 SMALA_RS05590 342d98e9a5707c6ff327a754c722827a 278 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 9 264 3.3E-73 T 29-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 SMALA_RS05590 342d98e9a5707c6ff327a754c722827a 278 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 4 271 17.635 T 29-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 SMALA_RS05590 342d98e9a5707c6ff327a754c722827a 278 Pfam PF02673 Bacitracin resistance protein BacA 9 266 6.0E-81 T 29-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 SMALA_RS22650 ddc58fef7bb77d909e482673ab3f2301 278 Pfam PF00557 Metallopeptidase family M24 11 249 2.5E-42 T 29-03-2018 IPR000994 Peptidase M24 SMALA_RS22650 ddc58fef7bb77d909e482673ab3f2301 278 SUPERFAMILY SSF55920 1 259 3.01E-71 T 29-03-2018 IPR000994 Peptidase M24 SMALA_RS22650 ddc58fef7bb77d909e482673ab3f2301 278 Hamap MF_01974 Methionine aminopeptidase [map]. 2 258 37.637 T 29-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 SMALA_RS22650 ddc58fef7bb77d909e482673ab3f2301 278 Gene3D G3DSA:3.90.230.10 1 272 1.3E-66 T 29-03-2018 SMALA_RS22650 ddc58fef7bb77d909e482673ab3f2301 278 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 3 257 3.9E-82 T 29-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 SMALA_RS22650 ddc58fef7bb77d909e482673ab3f2301 278 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 173 191 - T 29-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 SMALA_RS22650 ddc58fef7bb77d909e482673ab3f2301 278 PRINTS PR00599 Methionine aminopeptidase-1 signature 167 179 3.3E-20 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 SMALA_RS22650 ddc58fef7bb77d909e482673ab3f2301 278 PRINTS PR00599 Methionine aminopeptidase-1 signature 90 106 3.3E-20 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 SMALA_RS22650 ddc58fef7bb77d909e482673ab3f2301 278 PRINTS PR00599 Methionine aminopeptidase-1 signature 67 80 3.3E-20 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 SMALA_RS22650 ddc58fef7bb77d909e482673ab3f2301 278 PRINTS PR00599 Methionine aminopeptidase-1 signature 200 212 3.3E-20 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 SMALA_RS20805 3b2f1c9ec1f36e0981a97ad9406f7ee8 162 SUPERFAMILY SSF46785 4 106 7.02E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS20805 3b2f1c9ec1f36e0981a97ad9406f7ee8 162 Gene3D G3DSA:1.10.10.10 1 162 5.9E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS20805 3b2f1c9ec1f36e0981a97ad9406f7ee8 162 Pfam PF12802 MarR family 18 77 2.8E-9 T 29-03-2018 SMALA_RS24850 3be87ac7ece88bc32413deee8bc606b7 472 Gene3D G3DSA:1.10.275.10 13 143 1.4E-52 T 29-03-2018 IPR024083 Fumarase/histidase, N-terminal SMALA_RS24850 3be87ac7ece88bc32413deee8bc606b7 472 Gene3D G3DSA:1.10.40.30 423 472 2.7E-25 T 29-03-2018 SMALA_RS24850 3be87ac7ece88bc32413deee8bc606b7 472 Pfam PF10415 Fumarase C C-terminus 413 471 1.5E-21 T 29-03-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 SMALA_RS24850 3be87ac7ece88bc32413deee8bc606b7 472 SUPERFAMILY SSF48557 15 470 3.46E-146 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 SMALA_RS24850 3be87ac7ece88bc32413deee8bc606b7 472 PRINTS PR00145 Argininosuccinate lyase family signature 322 338 8.9E-5 T 29-03-2018 SMALA_RS24850 3be87ac7ece88bc32413deee8bc606b7 472 PRINTS PR00145 Argininosuccinate lyase family signature 180 200 8.9E-5 T 29-03-2018 SMALA_RS24850 3be87ac7ece88bc32413deee8bc606b7 472 Pfam PF00206 Lyase 23 347 2.0E-99 T 29-03-2018 IPR022761 Fumarate lyase, N-terminal SMALA_RS24850 3be87ac7ece88bc32413deee8bc606b7 472 Hamap MF_00743 Fumarate hydratase class II [fumC]. 15 472 81.88 T 29-03-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 SMALA_RS24850 3be87ac7ece88bc32413deee8bc606b7 472 ProSitePatterns PS00163 Fumarate lyases signature. 322 331 - T 29-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 SMALA_RS24850 3be87ac7ece88bc32413deee8bc606b7 472 Gene3D G3DSA:1.20.200.10 144 422 1.2E-80 T 29-03-2018 SMALA_RS24850 3be87ac7ece88bc32413deee8bc606b7 472 PRINTS PR00149 Fumarate lyase superfamily signature 139 157 8.5E-33 T 29-03-2018 IPR000362 Fumarate lyase family SMALA_RS24850 3be87ac7ece88bc32413deee8bc606b7 472 PRINTS PR00149 Fumarate lyase superfamily signature 322 338 8.5E-33 T 29-03-2018 IPR000362 Fumarate lyase family SMALA_RS24850 3be87ac7ece88bc32413deee8bc606b7 472 PRINTS PR00149 Fumarate lyase superfamily signature 185 203 8.5E-33 T 29-03-2018 IPR000362 Fumarate lyase family SMALA_RS24850 3be87ac7ece88bc32413deee8bc606b7 472 PRINTS PR00149 Fumarate lyase superfamily signature 276 303 8.5E-33 T 29-03-2018 IPR000362 Fumarate lyase family SMALA_RS08260 783f84023c3a54cd196e4f6c2873c4ca 485 Pfam PF03600 Citrate transporter 13 433 2.0E-50 T 29-03-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 SMALA_RS08260 783f84023c3a54cd196e4f6c2873c4ca 485 TIGRFAM TIGR00784 citMHS: citrate transporter 1 216 1.4E-81 T 29-03-2018 IPR014738 Citrate transporter GO:0015137|GO:0015746 SMALA_RS26865 94121d32415a2d62c97d112cf12a1232 215 SUPERFAMILY SSF55821 3 210 5.19E-58 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain SMALA_RS26865 94121d32415a2d62c97d112cf12a1232 215 Pfam PF01300 Telomere recombination 23 197 7.0E-48 T 29-03-2018 IPR006070 YrdC-like domain GO:0003725 SMALA_RS26865 94121d32415a2d62c97d112cf12a1232 215 Gene3D G3DSA:3.90.870.10 1 213 1.1E-67 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain SMALA_RS26865 94121d32415a2d62c97d112cf12a1232 215 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 13 207 1.8E-57 T 29-03-2018 IPR006070 YrdC-like domain GO:0003725 SMALA_RS22425 074714e6b82706b05373ef0ba937493a 278 SUPERFAMILY SSF82679 90 196 3.79E-34 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 SMALA_RS22425 074714e6b82706b05373ef0ba937493a 278 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 91 277 1.1E-53 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 SMALA_RS22425 074714e6b82706b05373ef0ba937493a 278 SMART SM00739 224 251 3.5E-4 T 29-03-2018 IPR005824 KOW SMALA_RS22425 074714e6b82706b05373ef0ba937493a 278 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 88 278 22.578 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 SMALA_RS22425 074714e6b82706b05373ef0ba937493a 278 SMART SM00738 88 196 2.7E-48 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 SMALA_RS22425 074714e6b82706b05373ef0ba937493a 278 Gene3D G3DSA:3.30.70.940 89 200 1.2E-35 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 SMALA_RS22425 074714e6b82706b05373ef0ba937493a 278 Gene3D G3DSA:2.30.30.30 219 278 5.2E-18 T 29-03-2018 IPR014722 Ribosomal protein L2 domain 2 SMALA_RS22425 074714e6b82706b05373ef0ba937493a 278 Pfam PF02357 Transcription termination factor nusG 90 192 3.6E-22 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 SMALA_RS22425 074714e6b82706b05373ef0ba937493a 278 PRINTS PR00338 Transcription termination factor NUSG signature 254 270 3.9E-18 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 SMALA_RS22425 074714e6b82706b05373ef0ba937493a 278 PRINTS PR00338 Transcription termination factor NUSG signature 236 251 3.9E-18 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 SMALA_RS22425 074714e6b82706b05373ef0ba937493a 278 PRINTS PR00338 Transcription termination factor NUSG signature 143 155 3.9E-18 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 SMALA_RS22425 074714e6b82706b05373ef0ba937493a 278 SUPERFAMILY SSF50104 223 277 4.61E-15 T 29-03-2018 IPR008991 Translation protein SH3-like domain SMALA_RS22425 074714e6b82706b05373ef0ba937493a 278 ProSitePatterns PS01014 Transcription termination factor nusG signature. 261 270 - T 29-03-2018 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site SMALA_RS20035 d79ed7de0f21ed8bcc34e54e73be49e1 222 Gene3D G3DSA:1.10.10.10 139 216 3.5E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS20035 d79ed7de0f21ed8bcc34e54e73be49e1 222 SUPERFAMILY SSF52172 6 135 3.98E-32 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS20035 d79ed7de0f21ed8bcc34e54e73be49e1 222 SMART SM00421 154 211 7.1E-21 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS20035 d79ed7de0f21ed8bcc34e54e73be49e1 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 157 171 4.5E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS20035 d79ed7de0f21ed8bcc34e54e73be49e1 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 187 199 4.5E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS20035 d79ed7de0f21ed8bcc34e54e73be49e1 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 171 187 4.5E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS20035 d79ed7de0f21ed8bcc34e54e73be49e1 222 Gene3D G3DSA:3.40.50.2300 6 138 8.1E-37 T 29-03-2018 SMALA_RS20035 d79ed7de0f21ed8bcc34e54e73be49e1 222 ProSitePatterns PS00622 LuxR-type HTH domain signature. 171 198 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS20035 d79ed7de0f21ed8bcc34e54e73be49e1 222 SUPERFAMILY SSF46894 147 215 1.36E-17 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS20035 d79ed7de0f21ed8bcc34e54e73be49e1 222 Pfam PF00072 Response regulator receiver domain 9 120 6.2E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS20035 d79ed7de0f21ed8bcc34e54e73be49e1 222 SMART SM00448 7 120 2.3E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS20035 d79ed7de0f21ed8bcc34e54e73be49e1 222 Pfam PF00196 Bacterial regulatory proteins, luxR family 157 210 6.9E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS21635 9daef060e17f82635e65d0e033b59eac 439 SMART SM00388 213 271 4.4E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS21635 9daef060e17f82635e65d0e033b59eac 439 Gene3D G3DSA:3.30.565.10 256 423 2.5E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS21635 9daef060e17f82635e65d0e033b59eac 439 SUPERFAMILY SSF158472 158 210 7.19E-5 T 29-03-2018 SMALA_RS21635 9daef060e17f82635e65d0e033b59eac 439 Pfam PF00512 His Kinase A (phospho-acceptor) domain 214 270 1.6E-10 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS21635 9daef060e17f82635e65d0e033b59eac 439 Pfam PF00672 HAMP domain 158 209 5.8E-8 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMALA_RS21635 9daef060e17f82635e65d0e033b59eac 439 Gene3D G3DSA:1.10.287.130 203 255 9.0E-12 T 29-03-2018 SMALA_RS21635 9daef060e17f82635e65d0e033b59eac 439 SUPERFAMILY SSF55874 260 400 1.14E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS21635 9daef060e17f82635e65d0e033b59eac 439 SMART SM00304 156 212 6.8E-7 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMALA_RS21635 9daef060e17f82635e65d0e033b59eac 439 SMART SM00387 309 425 3.5E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS21635 9daef060e17f82635e65d0e033b59eac 439 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 309 408 4.2E-11 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS21635 9daef060e17f82635e65d0e033b59eac 439 SUPERFAMILY SSF47384 196 269 1.1E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS24375 d5401dcfec0a14c3fd094fe97f2403cc 160 Pfam PF01047 MarR family 42 97 5.9E-14 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS24375 d5401dcfec0a14c3fd094fe97f2403cc 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 73 88 8.6E-7 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS24375 d5401dcfec0a14c3fd094fe97f2403cc 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 56 72 8.6E-7 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS24375 d5401dcfec0a14c3fd094fe97f2403cc 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 92 108 8.6E-7 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS24375 d5401dcfec0a14c3fd094fe97f2403cc 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 122 142 8.6E-7 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS24375 d5401dcfec0a14c3fd094fe97f2403cc 160 SUPERFAMILY SSF46785 36 145 1.44E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS24375 d5401dcfec0a14c3fd094fe97f2403cc 160 Gene3D G3DSA:1.10.10.10 5 147 2.0E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS24375 d5401dcfec0a14c3fd094fe97f2403cc 160 SMART SM00347 31 132 4.0E-16 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 Gene3D G3DSA:3.40.366.10 567 714 1.5E-49 T 29-03-2018 SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1213 1392 1.4E-50 T 29-03-2018 SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2758 2937 3.3E-58 T 29-03-2018 SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4325 4504 5.4E-54 T 29-03-2018 SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 SUPERFAMILY SSF55048 701 765 1.05E-12 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 3392 3509 4.8E-43 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1848 1965 1.7E-42 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 292 409 3.7E-43 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 SUPERFAMILY SSF51735 4101 4310 3.46E-48 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 Pfam PF08659 KR domain 2758 2936 1.6E-58 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 Pfam PF08659 KR domain 4325 4503 1.2E-57 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 Pfam PF08659 KR domain 1213 1391 1.2E-55 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 SUPERFAMILY SSF52151 3680 3805 1.2E-74 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 SUPERFAMILY SSF52151 3867 3969 1.2E-74 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 SUPERFAMILY SSF51735 4321 4551 3.64E-45 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 Pfam PF00698 Acyl transferase domain 3682 4005 2.5E-58 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 Pfam PF00698 Acyl transferase domain 2125 2447 2.0E-60 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 Pfam PF00698 Acyl transferase domain 573 895 1.1E-59 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 SUPERFAMILY SSF51735 1209 1467 1.23E-43 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 Gene3D G3DSA:3.40.366.10 2314 2435 5.4E-29 T 29-03-2018 SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 Gene3D G3DSA:3.40.366.10 3667 3854 3.5E-60 T 29-03-2018 SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 SUPERFAMILY SSF51735 989 1199 8.27E-48 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 SUPERFAMILY SSF52151 758 859 1.44E-76 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 SUPERFAMILY SSF52151 571 696 1.44E-76 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 SUPERFAMILY SSF53901 3131 3499 3.49E-104 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 SUPERFAMILY SSF51735 2538 2746 3.74E-50 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 Pfam PF00550 Phosphopantetheine attachment site 4613 4678 4.6E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 Pfam PF00550 Phosphopantetheine attachment site 1501 1566 3.1E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 Pfam PF00550 Phosphopantetheine attachment site 3043 3109 1.0E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 Gene3D G3DSA:3.40.366.10 756 868 3.1E-32 T 29-03-2018 SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 SUPERFAMILY SSF55048 3810 3874 1.26E-12 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 Gene3D G3DSA:3.40.47.10 1590 1852 3.6E-85 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 Gene3D G3DSA:3.40.47.10 3134 3396 7.8E-87 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 Gene3D G3DSA:3.40.47.10 28 296 7.4E-85 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 SUPERFAMILY SSF47336 3035 3148 3.53E-23 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 SUPERFAMILY SSF47336 1496 1605 5.37E-23 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1753 1769 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 SMART SM00825 Beta-ketoacyl synthase 37 462 4.2E-223 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 SMART SM00825 Beta-ketoacyl synthase 3136 3562 4.3E-223 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 SMART SM00825 Beta-ketoacyl synthase 1592 2018 1.1E-215 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 412 537 3.2E-16 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 3512 3646 8.1E-14 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1968 2087 8.9E-15 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 SUPERFAMILY SSF52151 2318 2411 2.3E-75 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 SUPERFAMILY SSF52151 2124 2254 2.3E-75 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 SUPERFAMILY SSF53901 1587 1963 1.59E-101 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 Gene3D G3DSA:1.10.1200.10 1493 1589 4.1E-18 T 29-03-2018 SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 Gene3D G3DSA:1.10.1200.10 3034 3133 1.4E-20 T 29-03-2018 SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 SMART SM00823 Phosphopantetheine attachment site 3041 3113 3.9E-31 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 SMART SM00823 Phosphopantetheine attachment site 4610 4682 1.4E-29 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 SMART SM00823 Phosphopantetheine attachment site 1498 1570 7.5E-32 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 3297 3313 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 SUPERFAMILY SSF55048 2253 2317 4.58E-12 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 Gene3D G3DSA:3.40.47.10 1855 2016 1.7E-59 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 Gene3D G3DSA:3.40.47.10 299 460 3.2E-61 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 Gene3D G3DSA:3.40.47.10 3399 3560 2.0E-59 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 Gene3D G3DSA:3.40.366.10 3855 4001 1.8E-39 T 29-03-2018 SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 Gene3D G3DSA:3.30.70.250 2267 2313 8.0E-19 T 29-03-2018 SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 Gene3D G3DSA:3.30.70.250 715 755 2.1E-19 T 29-03-2018 SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 Gene3D G3DSA:3.40.50.720 4318 4572 4.5E-50 T 29-03-2018 SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 Gene3D G3DSA:3.40.50.720 1206 1465 5.0E-47 T 29-03-2018 SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 Gene3D G3DSA:3.40.50.720 2750 3010 1.0E-48 T 29-03-2018 SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 SUPERFAMILY SSF47336 4604 4689 3.14E-20 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 SMART SM01294 4611 4678 1.7E-5 T 29-03-2018 SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 SMART SM01294 3042 3109 4.8E-7 T 29-03-2018 SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 SMART SM01294 1499 1566 8.0E-7 T 29-03-2018 SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 Gene3D G3DSA:1.10.1200.10 4573 4689 4.8E-18 T 29-03-2018 SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3134 3384 1.9E-92 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 35 284 3.5E-91 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1590 1840 4.6E-91 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3068 3083 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 Gene3D G3DSA:3.40.366.10 2122 2266 2.7E-51 T 29-03-2018 SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 3683 3987 4.1E-129 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 574 877 3.0E-135 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2126 2428 2.7E-131 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 SUPERFAMILY SSF53901 31 404 9.52E-104 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 197 213 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS37830 279587a04db54416e1147bd16bce6578 4762 SUPERFAMILY SSF51735 2756 2985 2.98E-45 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS00675 e10f110a8d4df43b2e4a1d9d4daa2637 267 SUPERFAMILY SSF52540 7 184 2.17E-35 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS00675 e10f110a8d4df43b2e4a1d9d4daa2637 267 ProSitePatterns PS00211 ABC transporters family signature. 91 105 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS00675 e10f110a8d4df43b2e4a1d9d4daa2637 267 Pfam PF00005 ABC transporter 4 119 2.3E-10 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS00675 e10f110a8d4df43b2e4a1d9d4daa2637 267 Gene3D G3DSA:3.40.50.300 35 211 1.5E-36 T 29-03-2018 SMALA_RS12355 9119fa195e66809c775b952d891e802b 426 Gene3D G3DSA:1.10.601.10 64 262 8.8E-68 T 29-03-2018 SMALA_RS12355 9119fa195e66809c775b952d891e802b 426 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 189 414 2.5E-38 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS12355 9119fa195e66809c775b952d891e802b 426 Pfam PF04542 Sigma-70 region 2 193 262 1.9E-23 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS12355 9119fa195e66809c775b952d891e802b 426 Gene3D G3DSA:1.10.10.10 355 426 1.4E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS12355 9119fa195e66809c775b952d891e802b 426 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 386 412 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS12355 9119fa195e66809c775b952d891e802b 426 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 217 230 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS12355 9119fa195e66809c775b952d891e802b 426 Pfam PF04545 Sigma-70, region 4 361 414 9.5E-20 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS12355 9119fa195e66809c775b952d891e802b 426 Gene3D G3DSA:1.10.10.10 263 313 1.6E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS12355 9119fa195e66809c775b952d891e802b 426 PRINTS PR00046 Major sigma-70 factor signature 386 401 9.5E-30 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS12355 9119fa195e66809c775b952d891e802b 426 PRINTS PR00046 Major sigma-70 factor signature 401 412 9.5E-30 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS12355 9119fa195e66809c775b952d891e802b 426 PRINTS PR00046 Major sigma-70 factor signature 241 249 9.5E-30 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS12355 9119fa195e66809c775b952d891e802b 426 PRINTS PR00046 Major sigma-70 factor signature 217 230 9.5E-30 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS12355 9119fa195e66809c775b952d891e802b 426 PRINTS PR00046 Major sigma-70 factor signature 365 377 9.5E-30 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS12355 9119fa195e66809c775b952d891e802b 426 SUPERFAMILY SSF88659 266 339 4.36E-18 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS12355 9119fa195e66809c775b952d891e802b 426 Pfam PF00140 Sigma-70 factor, region 1.2 128 161 8.4E-15 T 29-03-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS12355 9119fa195e66809c775b952d891e802b 426 Pfam PF04539 Sigma-70 region 3 272 348 1.6E-26 T 29-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS12355 9119fa195e66809c775b952d891e802b 426 SUPERFAMILY SSF88659 324 422 4.3E-28 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS12355 9119fa195e66809c775b952d891e802b 426 SUPERFAMILY SSF88946 125 263 1.22E-50 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS29730 91a1adf1a7b58ccde61ca036232b1cd1 918 Gene3D G3DSA:3.40.1060.10 231 362 8.2E-44 T 29-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS29730 91a1adf1a7b58ccde61ca036232b1cd1 918 Gene3D G3DSA:3.20.19.10 665 917 2.2E-90 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel SMALA_RS29730 91a1adf1a7b58ccde61ca036232b1cd1 918 Gene3D G3DSA:3.30.499.10 28 230 4.7E-74 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS29730 91a1adf1a7b58ccde61ca036232b1cd1 918 Gene3D G3DSA:3.30.499.10 363 588 4.8E-65 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS29730 91a1adf1a7b58ccde61ca036232b1cd1 918 Pfam PF00330 Aconitase family (aconitate hydratase) 64 574 5.2E-179 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS29730 91a1adf1a7b58ccde61ca036232b1cd1 918 PRINTS PR00415 Aconitase family signature 165 173 4.4E-42 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS29730 91a1adf1a7b58ccde61ca036232b1cd1 918 PRINTS PR00415 Aconitase family signature 194 207 4.4E-42 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS29730 91a1adf1a7b58ccde61ca036232b1cd1 918 PRINTS PR00415 Aconitase family signature 270 283 4.4E-42 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS29730 91a1adf1a7b58ccde61ca036232b1cd1 918 PRINTS PR00415 Aconitase family signature 505 518 4.4E-42 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS29730 91a1adf1a7b58ccde61ca036232b1cd1 918 PRINTS PR00415 Aconitase family signature 284 297 4.4E-42 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS29730 91a1adf1a7b58ccde61ca036232b1cd1 918 PRINTS PR00415 Aconitase family signature 208 223 4.4E-42 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS29730 91a1adf1a7b58ccde61ca036232b1cd1 918 PRINTS PR00415 Aconitase family signature 363 377 4.4E-42 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS29730 91a1adf1a7b58ccde61ca036232b1cd1 918 PRINTS PR00415 Aconitase family signature 141 154 4.4E-42 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS29730 91a1adf1a7b58ccde61ca036232b1cd1 918 PRINTS PR00415 Aconitase family signature 443 454 4.4E-42 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS29730 91a1adf1a7b58ccde61ca036232b1cd1 918 Pfam PF00694 Aconitase C-terminal domain 704 838 6.6E-43 T 29-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS29730 91a1adf1a7b58ccde61ca036232b1cd1 918 SUPERFAMILY SSF52016 643 915 7.85E-82 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel SMALA_RS29730 91a1adf1a7b58ccde61ca036232b1cd1 918 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 26 915 0.0 T 29-03-2018 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3|Reactome: R-HSA-917937 SMALA_RS29730 91a1adf1a7b58ccde61ca036232b1cd1 918 ProSitePatterns PS01244 Aconitase family signature 2. 505 518 - T 29-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 SMALA_RS29730 91a1adf1a7b58ccde61ca036232b1cd1 918 ProSitePatterns PS00450 Aconitase family signature 1. 439 455 - T 29-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 SMALA_RS29730 91a1adf1a7b58ccde61ca036232b1cd1 918 SUPERFAMILY SSF53732 4 639 8.37E-221 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS36465 0a87d6c3d1042ad518bf93a5ca28c998 209 Gene3D G3DSA:1.10.3300.10 14 203 1.3E-39 T 29-03-2018 IPR023286 ABATE domain SMALA_RS36465 0a87d6c3d1042ad518bf93a5ca28c998 209 Pfam PF11706 CGNR zinc finger 159 201 2.9E-16 T 29-03-2018 IPR021005 Zinc finger, CGNR SMALA_RS36465 0a87d6c3d1042ad518bf93a5ca28c998 209 Pfam PF07336 Putative stress-induced transcription regulator 25 153 3.0E-18 T 29-03-2018 IPR010852 Putative stress-induced transcription regulator SMALA_RS36465 0a87d6c3d1042ad518bf93a5ca28c998 209 SUPERFAMILY SSF160904 19 200 5.62E-35 T 29-03-2018 SMALA_RS03885 a5708c828216db15a3326c5db9ac148a 812 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 594 724 2.3E-16 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 SMALA_RS03885 a5708c828216db15a3326c5db9ac148a 812 PRINTS PR00819 CbxX/CfqX superfamily signature 630 644 1.2E-48 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 SMALA_RS03885 a5708c828216db15a3326c5db9ac148a 812 PRINTS PR00819 CbxX/CfqX superfamily signature 713 732 1.2E-48 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 SMALA_RS03885 a5708c828216db15a3326c5db9ac148a 812 PRINTS PR00819 CbxX/CfqX superfamily signature 770 782 1.2E-48 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 SMALA_RS03885 a5708c828216db15a3326c5db9ac148a 812 PRINTS PR00819 CbxX/CfqX superfamily signature 552 566 1.2E-48 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 SMALA_RS03885 a5708c828216db15a3326c5db9ac148a 812 PRINTS PR00819 CbxX/CfqX superfamily signature 696 713 1.2E-48 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 SMALA_RS03885 a5708c828216db15a3326c5db9ac148a 812 PRINTS PR00819 CbxX/CfqX superfamily signature 644 663 1.2E-48 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 SMALA_RS03885 a5708c828216db15a3326c5db9ac148a 812 PRINTS PR00819 CbxX/CfqX superfamily signature 675 687 1.2E-48 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 SMALA_RS03885 a5708c828216db15a3326c5db9ac148a 812 PRINTS PR00819 CbxX/CfqX superfamily signature 592 607 1.2E-48 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 SMALA_RS03885 a5708c828216db15a3326c5db9ac148a 812 Gene3D G3DSA:3.40.50.300 538 725 5.8E-24 T 29-03-2018 SMALA_RS03885 a5708c828216db15a3326c5db9ac148a 812 SUPERFAMILY SSF52540 551 782 1.39E-34 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS03885 a5708c828216db15a3326c5db9ac148a 812 SMART SM00382 589 728 1.6E-5 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS03885 a5708c828216db15a3326c5db9ac148a 812 Pfam PF13229 Right handed beta helix region 124 244 9.7E-14 T 29-03-2018 SMALA_RS03885 a5708c828216db15a3326c5db9ac148a 812 Pfam PF13229 Right handed beta helix region 358 486 1.8E-12 T 29-03-2018 SMALA_RS03885 a5708c828216db15a3326c5db9ac148a 812 SUPERFAMILY SSF51126 21 242 2.32E-25 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor SMALA_RS03885 a5708c828216db15a3326c5db9ac148a 812 Gene3D G3DSA:2.160.20.10 239 401 3.0E-14 T 29-03-2018 IPR012334 Pectin lyase fold SMALA_RS03885 a5708c828216db15a3326c5db9ac148a 812 SMART SM00710 153 175 750.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat SMALA_RS03885 a5708c828216db15a3326c5db9ac148a 812 SMART SM00710 176 198 540.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat SMALA_RS03885 a5708c828216db15a3326c5db9ac148a 812 SMART SM00710 432 454 29.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat SMALA_RS03885 a5708c828216db15a3326c5db9ac148a 812 SMART SM00710 455 477 6300.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat SMALA_RS03885 a5708c828216db15a3326c5db9ac148a 812 SMART SM00710 269 291 1900.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat SMALA_RS03885 a5708c828216db15a3326c5db9ac148a 812 SMART SM00710 130 152 150.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat SMALA_RS03885 a5708c828216db15a3326c5db9ac148a 812 SMART SM00710 409 431 68.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat SMALA_RS03885 a5708c828216db15a3326c5db9ac148a 812 SMART SM00710 200 222 5300.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat SMALA_RS03885 a5708c828216db15a3326c5db9ac148a 812 SMART SM00710 223 245 1200.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat SMALA_RS03885 a5708c828216db15a3326c5db9ac148a 812 SMART SM00710 246 268 5600.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat SMALA_RS03885 a5708c828216db15a3326c5db9ac148a 812 SMART SM00710 341 363 6600.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat SMALA_RS03885 a5708c828216db15a3326c5db9ac148a 812 SMART SM00710 387 408 47.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat SMALA_RS03885 a5708c828216db15a3326c5db9ac148a 812 SMART SM00710 364 385 5000.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat SMALA_RS03885 a5708c828216db15a3326c5db9ac148a 812 SMART SM00722 42 174 0.19 T 29-03-2018 IPR006633 Carbohydrate-binding/sugar hydrolysis domain SMALA_RS03885 a5708c828216db15a3326c5db9ac148a 812 SMART SM00722 315 476 1.6E-6 T 29-03-2018 IPR006633 Carbohydrate-binding/sugar hydrolysis domain SMALA_RS03885 a5708c828216db15a3326c5db9ac148a 812 Gene3D G3DSA:2.160.20.10 9 238 7.8E-29 T 29-03-2018 IPR012334 Pectin lyase fold SMALA_RS03885 a5708c828216db15a3326c5db9ac148a 812 SUPERFAMILY SSF51126 308 486 2.54E-14 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor SMALA_RS03885 a5708c828216db15a3326c5db9ac148a 812 Gene3D G3DSA:2.160.20.10 402 524 5.7E-9 T 29-03-2018 IPR012334 Pectin lyase fold SMALA_RS32875 881b903f4d5c765d669f585e58a9f55d 222 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 69 91 - T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 SMALA_RS32875 881b903f4d5c765d669f585e58a9f55d 222 Pfam PF01066 CDP-alcohol phosphatidyltransferase 27 91 1.3E-9 T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 SMALA_RS05700 fc0d2264d7f49d654ea534633a6dfc0c 710 Pfam PF01968 Hydantoinase/oxoprolinase 195 502 1.0E-78 T 29-03-2018 IPR002821 Hydantoinase/oxoprolinase GO:0016787 Reactome: R-HSA-174403 SMALA_RS05700 fc0d2264d7f49d654ea534633a6dfc0c 710 Gene3D G3DSA:3.30.420.40 2 159 6.0E-9 T 29-03-2018 SMALA_RS05700 fc0d2264d7f49d654ea534633a6dfc0c 710 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 8 174 3.4E-27 T 29-03-2018 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403 SMALA_RS05700 fc0d2264d7f49d654ea534633a6dfc0c 710 Gene3D G3DSA:3.30.420.150 254 533 1.0E-7 T 29-03-2018 SMALA_RS05700 fc0d2264d7f49d654ea534633a6dfc0c 710 SUPERFAMILY SSF53067 8 88 3.79E-10 T 29-03-2018 SMALA_RS05700 fc0d2264d7f49d654ea534633a6dfc0c 710 SUPERFAMILY SSF53067 396 496 3.79E-10 T 29-03-2018 SMALA_RS05700 fc0d2264d7f49d654ea534633a6dfc0c 710 SUPERFAMILY SSF53067 253 302 3.79E-10 T 29-03-2018 SMALA_RS16325 e189d08da180c5a8fe544ab03e47631d 501 Gene3D G3DSA:1.10.630.10 28 421 3.1E-35 T 29-03-2018 SMALA_RS16325 e189d08da180c5a8fe544ab03e47631d 501 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 356 365 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMALA_RS16325 e189d08da180c5a8fe544ab03e47631d 501 PRINTS PR00359 B-class P450 signature 164 180 5.8E-10 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS16325 e189d08da180c5a8fe544ab03e47631d 501 PRINTS PR00359 B-class P450 signature 214 236 5.8E-10 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS16325 e189d08da180c5a8fe544ab03e47631d 501 PRINTS PR00359 B-class P450 signature 354 363 5.8E-10 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS16325 e189d08da180c5a8fe544ab03e47631d 501 PRINTS PR00359 B-class P450 signature 363 374 5.8E-10 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS16325 e189d08da180c5a8fe544ab03e47631d 501 PRINTS PR00359 B-class P450 signature 118 129 5.8E-10 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS16325 e189d08da180c5a8fe544ab03e47631d 501 SUPERFAMILY SSF48264 16 416 8.91E-56 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS17175 49506239eb0874d9cca07cc00f539319 230 Gene3D G3DSA:1.10.10.10 1 73 5.3E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS17175 49506239eb0874d9cca07cc00f539319 230 SUPERFAMILY SSF47979 65 137 6.41E-26 T 29-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 SMALA_RS17175 49506239eb0874d9cca07cc00f539319 230 Pfam PF04023 FeoA domain 162 228 8.9E-7 T 29-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 SMALA_RS17175 49506239eb0874d9cca07cc00f539319 230 SUPERFAMILY SSF50037 130 229 4.35E-24 T 29-03-2018 IPR008988 Transcriptional repressor, C-terminal SMALA_RS17175 49506239eb0874d9cca07cc00f539319 230 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 4 62 3.5E-19 T 29-03-2018 IPR022687 DTXR-type HTH domain GO:0003677 SMALA_RS17175 49506239eb0874d9cca07cc00f539319 230 SUPERFAMILY SSF46785 3 62 1.22E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS17175 49506239eb0874d9cca07cc00f539319 230 SMART SM00529 26 125 4.1E-47 T 29-03-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 SMALA_RS17175 49506239eb0874d9cca07cc00f539319 230 SMART SM00899 153 229 4.4E-7 T 29-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 SMALA_RS17175 49506239eb0874d9cca07cc00f539319 230 Gene3D G3DSA:2.30.30.90 130 229 7.7E-23 T 29-03-2018 SMALA_RS17175 49506239eb0874d9cca07cc00f539319 230 Gene3D G3DSA:1.10.60.10 75 129 5.2E-24 T 29-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 SMALA_RS17175 49506239eb0874d9cca07cc00f539319 230 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 65 133 2.9E-29 T 29-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 SMALA_RS36540 0e599dcd8a02550b0698ad803af18743 163 Gene3D G3DSA:1.10.10.10 3 60 2.2E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS36540 0e599dcd8a02550b0698ad803af18743 163 Pfam PF13404 AsnC-type helix-turn-helix domain 9 49 1.0E-16 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMALA_RS36540 0e599dcd8a02550b0698ad803af18743 163 Gene3D G3DSA:3.30.70.920 61 148 2.2E-17 T 29-03-2018 SMALA_RS36540 0e599dcd8a02550b0698ad803af18743 163 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 8 24 1.3E-10 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMALA_RS36540 0e599dcd8a02550b0698ad803af18743 163 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 24 35 1.3E-10 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMALA_RS36540 0e599dcd8a02550b0698ad803af18743 163 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 35 54 1.3E-10 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMALA_RS36540 0e599dcd8a02550b0698ad803af18743 163 SUPERFAMILY SSF54909 69 147 5.36E-15 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel SMALA_RS36540 0e599dcd8a02550b0698ad803af18743 163 SMART SM00344 8 115 3.5E-33 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 SMALA_RS36540 0e599dcd8a02550b0698ad803af18743 163 Pfam PF01037 Lrp/AsnC ligand binding domain 74 144 5.8E-15 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain SMALA_RS36540 0e599dcd8a02550b0698ad803af18743 163 SUPERFAMILY SSF46785 8 68 7.5E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS01465 078aca372727dd9588fcff69b8bc046d 521 Gene3D G3DSA:1.20.1250.20 263 502 1.8E-30 T 29-03-2018 SMALA_RS01465 078aca372727dd9588fcff69b8bc046d 521 PRINTS PR01036 Tetracycline resistance protein TetB signature 118 138 1.1E-8 T 29-03-2018 SMALA_RS01465 078aca372727dd9588fcff69b8bc046d 521 PRINTS PR01036 Tetracycline resistance protein TetB signature 148 172 1.1E-8 T 29-03-2018 SMALA_RS01465 078aca372727dd9588fcff69b8bc046d 521 PRINTS PR01036 Tetracycline resistance protein TetB signature 314 338 1.1E-8 T 29-03-2018 SMALA_RS01465 078aca372727dd9588fcff69b8bc046d 521 PRINTS PR01036 Tetracycline resistance protein TetB signature 413 432 1.1E-8 T 29-03-2018 SMALA_RS01465 078aca372727dd9588fcff69b8bc046d 521 PRINTS PR01036 Tetracycline resistance protein TetB signature 28 52 1.1E-8 T 29-03-2018 SMALA_RS01465 078aca372727dd9588fcff69b8bc046d 521 Pfam PF07690 Major Facilitator Superfamily 29 422 1.5E-52 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS01465 078aca372727dd9588fcff69b8bc046d 521 Gene3D G3DSA:1.20.1250.20 22 212 6.7E-37 T 29-03-2018 SMALA_RS01465 078aca372727dd9588fcff69b8bc046d 521 SUPERFAMILY SSF103473 260 432 7.46E-70 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS01465 078aca372727dd9588fcff69b8bc046d 521 SUPERFAMILY SSF103473 471 496 7.46E-70 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS01465 078aca372727dd9588fcff69b8bc046d 521 SUPERFAMILY SSF103473 23 213 7.46E-70 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS01465 078aca372727dd9588fcff69b8bc046d 521 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 26 457 6.8E-76 T 29-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 SMALA_RS40020 3e440ccd75b478e0d51f90264c2653e4 317 Gene3D G3DSA:3.40.50.720 143 251 1.8E-19 T 29-03-2018 SMALA_RS40020 3e440ccd75b478e0d51f90264c2653e4 317 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 83 1.1E-5 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS40020 3e440ccd75b478e0d51f90264c2653e4 317 SUPERFAMILY SSF50129 1 144 2.13E-34 T 29-03-2018 IPR011032 GroES-like SMALA_RS40020 3e440ccd75b478e0d51f90264c2653e4 317 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 135 156 - T 29-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 SMALA_RS40020 3e440ccd75b478e0d51f90264c2653e4 317 Pfam PF00107 Zinc-binding dehydrogenase 146 260 2.7E-24 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMALA_RS40020 3e440ccd75b478e0d51f90264c2653e4 317 SUPERFAMILY SSF51735 107 282 6.38E-36 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS40020 3e440ccd75b478e0d51f90264c2653e4 317 Gene3D G3DSA:3.90.180.10 252 317 0.17 T 29-03-2018 SMALA_RS40020 3e440ccd75b478e0d51f90264c2653e4 317 Gene3D G3DSA:3.90.180.10 1 142 5.9E-44 T 29-03-2018 SMALA_RS40020 3e440ccd75b478e0d51f90264c2653e4 317 SMART SM00829 10 315 1.1E-22 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS08560 b4d2b0201ca8ee5d7ce7a556a95ea2e1 395 SUPERFAMILY SSF47203 242 390 5.15E-40 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMALA_RS08560 b4d2b0201ca8ee5d7ce7a556a95ea2e1 395 Gene3D G3DSA:2.40.110.10 138 229 2.2E-35 T 29-03-2018 SMALA_RS08560 b4d2b0201ca8ee5d7ce7a556a95ea2e1 395 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 23 135 2.9E-29 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS08560 b4d2b0201ca8ee5d7ce7a556a95ea2e1 395 Gene3D G3DSA:1.20.140.10 230 393 4.7E-37 T 29-03-2018 SMALA_RS08560 b4d2b0201ca8ee5d7ce7a556a95ea2e1 395 SUPERFAMILY SSF56645 9 240 5.37E-76 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMALA_RS08560 b4d2b0201ca8ee5d7ce7a556a95ea2e1 395 Gene3D G3DSA:1.10.540.10 2 137 5.4E-33 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS08560 b4d2b0201ca8ee5d7ce7a556a95ea2e1 395 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 139 229 6.7E-25 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 SMALA_RS08560 b4d2b0201ca8ee5d7ce7a556a95ea2e1 395 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 242 388 2.0E-29 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMALA_RS40650 9c00273dc3befefe0ad15363b40d57c7 452 Pfam PF13185 GAF domain 66 201 2.8E-16 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS40650 9c00273dc3befefe0ad15363b40d57c7 452 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 256 444 1.1E-41 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS40650 9c00273dc3befefe0ad15363b40d57c7 452 Gene3D G3DSA:3.60.40.10 206 445 3.6E-29 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS40650 9c00273dc3befefe0ad15363b40d57c7 452 SMART SM00331 227 444 3.6E-28 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS40650 9c00273dc3befefe0ad15363b40d57c7 452 SMART SM00065 63 210 9.6E-16 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS40650 9c00273dc3befefe0ad15363b40d57c7 452 SUPERFAMILY SSF81606 245 444 6.02E-6 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS40650 9c00273dc3befefe0ad15363b40d57c7 452 Gene3D G3DSA:3.30.450.40 35 205 1.1E-31 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS40650 9c00273dc3befefe0ad15363b40d57c7 452 SUPERFAMILY SSF55781 45 214 6.32E-32 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS30340 0e8faec512f047d398fb6e9b5447601a 3705 SUPERFAMILY SSF53901 1030 1405 1.73E-99 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS30340 0e8faec512f047d398fb6e9b5447601a 3705 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1986 2001 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS30340 0e8faec512f047d398fb6e9b5447601a 3705 Gene3D G3DSA:1.10.1200.10 1941 2039 6.0E-17 T 29-03-2018 SMALA_RS30340 0e8faec512f047d398fb6e9b5447601a 3705 SMART SM00825 Beta-ketoacyl synthase 1036 1460 4.4E-218 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS30340 0e8faec512f047d398fb6e9b5447601a 3705 SMART SM00825 Beta-ketoacyl synthase 2059 2484 1.7E-214 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS30340 0e8faec512f047d398fb6e9b5447601a 3705 SMART SM00825 Beta-ketoacyl synthase 17 441 4.8E-187 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS30340 0e8faec512f047d398fb6e9b5447601a 3705 SUPERFAMILY SSF52151 568 695 1.05E-69 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS30340 0e8faec512f047d398fb6e9b5447601a 3705 SUPERFAMILY SSF52151 758 848 1.05E-69 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS30340 0e8faec512f047d398fb6e9b5447601a 3705 Gene3D G3DSA:1.10.1200.10 3505 3599 4.1E-19 T 29-03-2018 SMALA_RS30340 0e8faec512f047d398fb6e9b5447601a 3705 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1034 1282 2.2E-88 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS30340 0e8faec512f047d398fb6e9b5447601a 3705 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2057 2306 4.1E-89 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS30340 0e8faec512f047d398fb6e9b5447601a 3705 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 16 263 2.3E-79 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS30340 0e8faec512f047d398fb6e9b5447601a 3705 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 2219 2235 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS30340 0e8faec512f047d398fb6e9b5447601a 3705 SUPERFAMILY SSF47336 3519 3603 3.93E-21 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS30340 0e8faec512f047d398fb6e9b5447601a 3705 SUPERFAMILY SSF47336 943 1049 4.32E-20 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS30340 0e8faec512f047d398fb6e9b5447601a 3705 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2589 2880 1.8E-119 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS30340 0e8faec512f047d398fb6e9b5447601a 3705 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 570 860 1.3E-113 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS30340 0e8faec512f047d398fb6e9b5447601a 3705 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1571 1868 7.6E-116 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS30340 0e8faec512f047d398fb6e9b5447601a 3705 Gene3D G3DSA:3.30.70.250 706 745 1.1E-10 T 29-03-2018 SMALA_RS30340 0e8faec512f047d398fb6e9b5447601a 3705 Pfam PF00698 Acyl transferase domain 1569 1887 4.4E-80 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS30340 0e8faec512f047d398fb6e9b5447601a 3705 Pfam PF00698 Acyl transferase domain 2587 2891 8.6E-83 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS30340 0e8faec512f047d398fb6e9b5447601a 3705 Pfam PF00698 Acyl transferase domain 568 877 1.3E-75 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS30340 0e8faec512f047d398fb6e9b5447601a 3705 SUPERFAMILY SSF47336 1953 2040 2.88E-18 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS30340 0e8faec512f047d398fb6e9b5447601a 3705 Gene3D G3DSA:3.40.47.10 2049 2318 1.5E-84 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS30340 0e8faec512f047d398fb6e9b5447601a 3705 Gene3D G3DSA:3.40.47.10 1035 1294 2.5E-84 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS30340 0e8faec512f047d398fb6e9b5447601a 3705 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3226 3405 9.9E-52 T 29-03-2018 SMALA_RS30340 0e8faec512f047d398fb6e9b5447601a 3705 Gene3D G3DSA:1.10.1200.10 938 1034 2.4E-17 T 29-03-2018 SMALA_RS30340 0e8faec512f047d398fb6e9b5447601a 3705 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1195 1211 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS30340 0e8faec512f047d398fb6e9b5447601a 3705 Gene3D G3DSA:3.30.70.250 2726 2767 2.2E-15 T 29-03-2018 SMALA_RS30340 0e8faec512f047d398fb6e9b5447601a 3705 Gene3D G3DSA:3.40.366.10 746 856 8.4E-24 T 29-03-2018 SMALA_RS30340 0e8faec512f047d398fb6e9b5447601a 3705 Pfam PF00550 Phosphopantetheine attachment site 946 1012 7.0E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS30340 0e8faec512f047d398fb6e9b5447601a 3705 Pfam PF00550 Phosphopantetheine attachment site 1960 2027 1.9E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS30340 0e8faec512f047d398fb6e9b5447601a 3705 Pfam PF00550 Phosphopantetheine attachment site 3528 3594 1.5E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS30340 0e8faec512f047d398fb6e9b5447601a 3705 SUPERFAMILY SSF53901 2054 2429 8.53E-103 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS30340 0e8faec512f047d398fb6e9b5447601a 3705 Gene3D G3DSA:3.40.47.10 18 276 2.3E-79 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS30340 0e8faec512f047d398fb6e9b5447601a 3705 SMART SM00823 Phosphopantetheine attachment site 1959 2031 7.4E-27 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS30340 0e8faec512f047d398fb6e9b5447601a 3705 SMART SM00823 Phosphopantetheine attachment site 944 1016 3.8E-22 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS30340 0e8faec512f047d398fb6e9b5447601a 3705 SMART SM00823 Phosphopantetheine attachment site 3526 3598 1.1E-28 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS30340 0e8faec512f047d398fb6e9b5447601a 3705 SUPERFAMILY SSF52151 2778 2870 2.88E-71 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS30340 0e8faec512f047d398fb6e9b5447601a 3705 SUPERFAMILY SSF52151 2587 2714 2.88E-71 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS30340 0e8faec512f047d398fb6e9b5447601a 3705 Gene3D G3DSA:3.30.70.250 1707 1748 3.3E-15 T 29-03-2018 SMALA_RS30340 0e8faec512f047d398fb6e9b5447601a 3705 SUPERFAMILY SSF51735 2992 3211 3.31E-37 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS30340 0e8faec512f047d398fb6e9b5447601a 3705 Gene3D G3DSA:3.40.366.10 1565 1706 3.4E-47 T 29-03-2018 SMALA_RS30340 0e8faec512f047d398fb6e9b5447601a 3705 Gene3D G3DSA:3.40.366.10 564 705 1.6E-44 T 29-03-2018 SMALA_RS30340 0e8faec512f047d398fb6e9b5447601a 3705 Gene3D G3DSA:3.40.366.10 2768 2885 1.4E-30 T 29-03-2018 SMALA_RS30340 0e8faec512f047d398fb6e9b5447601a 3705 Gene3D G3DSA:3.40.47.10 2321 2482 2.3E-61 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS30340 0e8faec512f047d398fb6e9b5447601a 3705 Gene3D G3DSA:3.40.47.10 278 439 4.7E-57 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS30340 0e8faec512f047d398fb6e9b5447601a 3705 Gene3D G3DSA:3.40.47.10 1297 1458 4.5E-64 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS30340 0e8faec512f047d398fb6e9b5447601a 3705 Gene3D G3DSA:3.40.50.720 3224 3478 4.8E-53 T 29-03-2018 SMALA_RS30340 0e8faec512f047d398fb6e9b5447601a 3705 SUPERFAMILY SSF53901 12 381 4.52E-88 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS30340 0e8faec512f047d398fb6e9b5447601a 3705 SUPERFAMILY SSF55048 1695 1759 2.35E-10 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS30340 0e8faec512f047d398fb6e9b5447601a 3705 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 272 388 9.1E-38 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS30340 0e8faec512f047d398fb6e9b5447601a 3705 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1290 1407 2.0E-44 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS30340 0e8faec512f047d398fb6e9b5447601a 3705 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2314 2431 3.9E-43 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS30340 0e8faec512f047d398fb6e9b5447601a 3705 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3553 3568 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS30340 0e8faec512f047d398fb6e9b5447601a 3705 SUPERFAMILY SSF52151 1760 1859 7.06E-70 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS30340 0e8faec512f047d398fb6e9b5447601a 3705 SUPERFAMILY SSF52151 1569 1696 7.06E-70 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS30340 0e8faec512f047d398fb6e9b5447601a 3705 SUPERFAMILY SSF55048 2713 2777 1.83E-10 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS30340 0e8faec512f047d398fb6e9b5447601a 3705 Pfam PF08659 KR domain 3226 3403 2.6E-55 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS30340 0e8faec512f047d398fb6e9b5447601a 3705 Gene3D G3DSA:3.40.366.10 1749 1875 3.9E-28 T 29-03-2018 SMALA_RS30340 0e8faec512f047d398fb6e9b5447601a 3705 Gene3D G3DSA:3.40.366.10 2586 2725 3.2E-45 T 29-03-2018 SMALA_RS30340 0e8faec512f047d398fb6e9b5447601a 3705 SUPERFAMILY SSF51735 3226 3459 4.91E-47 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS30340 0e8faec512f047d398fb6e9b5447601a 3705 SMART SM01294 945 1012 5.6E-4 T 29-03-2018 SMALA_RS30340 0e8faec512f047d398fb6e9b5447601a 3705 SMART SM01294 3527 3594 7.6E-7 T 29-03-2018 SMALA_RS30340 0e8faec512f047d398fb6e9b5447601a 3705 SMART SM01294 1960 2027 1.4E-5 T 29-03-2018 SMALA_RS30340 0e8faec512f047d398fb6e9b5447601a 3705 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1410 1531 7.8E-13 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS30340 0e8faec512f047d398fb6e9b5447601a 3705 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 391 532 4.5E-14 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS30340 0e8faec512f047d398fb6e9b5447601a 3705 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2434 2550 1.1E-17 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS30340 0e8faec512f047d398fb6e9b5447601a 3705 SUPERFAMILY SSF55048 693 753 8.5E-8 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS33360 4557db1d219330bb7ff488f3230b5096 715 SUPERFAMILY SSF55785 143 269 9.95E-22 T 29-03-2018 IPR000014 PAS domain SMALA_RS33360 4557db1d219330bb7ff488f3230b5096 715 Gene3D G3DSA:3.30.450.20 124 283 8.9E-32 T 29-03-2018 SMALA_RS33360 4557db1d219330bb7ff488f3230b5096 715 SUPERFAMILY SSF141868 459 709 6.93E-83 T 29-03-2018 IPR001633 EAL domain SMALA_RS33360 4557db1d219330bb7ff488f3230b5096 715 Pfam PF00563 EAL domain 461 700 1.3E-70 T 29-03-2018 IPR001633 EAL domain SMALA_RS33360 4557db1d219330bb7ff488f3230b5096 715 Pfam PF08448 PAS fold 166 273 1.5E-11 T 29-03-2018 IPR013656 PAS fold-4 SMALA_RS33360 4557db1d219330bb7ff488f3230b5096 715 SUPERFAMILY SSF55073 287 444 2.62E-40 T 29-03-2018 IPR029787 Nucleotide cyclase SMALA_RS33360 4557db1d219330bb7ff488f3230b5096 715 Gene3D G3DSA:3.30.70.270 284 446 9.1E-55 T 29-03-2018 SMALA_RS33360 4557db1d219330bb7ff488f3230b5096 715 SMART SM00091 156 222 3.4E-6 T 29-03-2018 IPR000014 PAS domain SMALA_RS33360 4557db1d219330bb7ff488f3230b5096 715 SMART SM00052 453 705 2.5E-103 T 29-03-2018 IPR001633 EAL domain SMALA_RS33360 4557db1d219330bb7ff488f3230b5096 715 Gene3D G3DSA:3.20.20.450 447 715 2.5E-98 T 29-03-2018 IPR001633 EAL domain SMALA_RS33360 4557db1d219330bb7ff488f3230b5096 715 SMART SM00267 271 443 1.6E-52 T 29-03-2018 IPR000160 GGDEF domain SMALA_RS33360 4557db1d219330bb7ff488f3230b5096 715 Pfam PF00990 Diguanylate cyclase, GGDEF domain 282 439 2.4E-39 T 29-03-2018 IPR000160 GGDEF domain SMALA_RS33360 4557db1d219330bb7ff488f3230b5096 715 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 280 443 9.9E-35 T 29-03-2018 IPR000160 GGDEF domain SMALA_RS33360 4557db1d219330bb7ff488f3230b5096 715 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 153 278 1.6E-17 T 29-03-2018 IPR000014 PAS domain SMALA_RS10855 e9d037c139eebcd834a39c5c2125370f 463 PRINTS PR00110 Alpha-amylase signature 289 301 1.3E-22 T 29-03-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 SMALA_RS10855 e9d037c139eebcd834a39c5c2125370f 463 PRINTS PR00110 Alpha-amylase signature 231 249 1.3E-22 T 29-03-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 SMALA_RS10855 e9d037c139eebcd834a39c5c2125370f 463 PRINTS PR00110 Alpha-amylase signature 81 98 1.3E-22 T 29-03-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 SMALA_RS10855 e9d037c139eebcd834a39c5c2125370f 463 PRINTS PR00110 Alpha-amylase signature 113 124 1.3E-22 T 29-03-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 SMALA_RS10855 e9d037c139eebcd834a39c5c2125370f 463 PRINTS PR00110 Alpha-amylase signature 202 213 1.3E-22 T 29-03-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 SMALA_RS10855 e9d037c139eebcd834a39c5c2125370f 463 Gene3D G3DSA:2.60.40.1180 382 460 7.1E-29 T 29-03-2018 SMALA_RS10855 e9d037c139eebcd834a39c5c2125370f 463 SUPERFAMILY SSF51011 380 460 2.94E-27 T 29-03-2018 SMALA_RS10855 e9d037c139eebcd834a39c5c2125370f 463 SUPERFAMILY SSF51445 36 377 3.65E-81 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS10855 e9d037c139eebcd834a39c5c2125370f 463 SMART SM00632 384 460 1.1E-36 T 29-03-2018 IPR031319 Alpha-amylase, C-terminal domain Reactome: R-HSA-189085 SMALA_RS10855 e9d037c139eebcd834a39c5c2125370f 463 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 387 456 1.5E-8 T 29-03-2018 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 SMALA_RS10855 e9d037c139eebcd834a39c5c2125370f 463 SMART SM00642 38 375 3.0E-78 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SMALA_RS10855 e9d037c139eebcd834a39c5c2125370f 463 Gene3D G3DSA:3.20.20.80 34 380 1.0E-68 T 29-03-2018 SMALA_RS10855 e9d037c139eebcd834a39c5c2125370f 463 Pfam PF00128 Alpha amylase, catalytic domain 90 338 1.2E-18 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SMALA_RS05045 f33dfe8a78c77e7d12ab9143a6ce4de0 492 SUPERFAMILY SSF103473 21 207 2.22E-25 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS05045 f33dfe8a78c77e7d12ab9143a6ce4de0 492 Gene3D G3DSA:1.20.1250.20 16 212 9.2E-23 T 29-03-2018 SMALA_RS05045 f33dfe8a78c77e7d12ab9143a6ce4de0 492 SUPERFAMILY SSF103473 217 480 1.57E-17 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS05045 f33dfe8a78c77e7d12ab9143a6ce4de0 492 Gene3D G3DSA:1.20.1250.20 272 491 3.1E-17 T 29-03-2018 SMALA_RS05045 f33dfe8a78c77e7d12ab9143a6ce4de0 492 Pfam PF07690 Major Facilitator Superfamily 42 299 2.8E-17 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS10880 ef41d689088d4209ebcf5093047863fe 553 Gene3D G3DSA:3.20.20.470 195 357 1.8E-39 T 29-03-2018 SMALA_RS10880 ef41d689088d4209ebcf5093047863fe 553 Gene3D G3DSA:3.20.20.80 7 136 5.1E-46 T 29-03-2018 SMALA_RS10880 ef41d689088d4209ebcf5093047863fe 553 Gene3D G3DSA:3.20.20.80 358 489 1.7E-24 T 29-03-2018 SMALA_RS10880 ef41d689088d4209ebcf5093047863fe 553 SUPERFAMILY SSF51445 20 486 1.73E-126 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS10880 ef41d689088d4209ebcf5093047863fe 553 Pfam PF00128 Alpha amylase, catalytic domain 45 392 1.0E-75 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SMALA_RS10880 ef41d689088d4209ebcf5093047863fe 553 Pfam PF11941 Domain of unknown function (DUF3459) 472 551 3.4E-5 T 29-03-2018 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) SMALA_RS10880 ef41d689088d4209ebcf5093047863fe 553 SMART SM00642 30 423 1.4E-126 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SMALA_RS10880 ef41d689088d4209ebcf5093047863fe 553 Gene3D G3DSA:3.90.400.10 137 194 2.2E-28 T 29-03-2018 SMALA_RS15965 02b08ff1bafadd99033b0cef26dc3743 174 SMART SM01001 4 153 9.1E-100 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 SMALA_RS15965 02b08ff1bafadd99033b0cef26dc3743 174 SUPERFAMILY SSF52255 5 162 7.72E-67 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 SMALA_RS15965 02b08ff1bafadd99033b0cef26dc3743 174 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 6 157 32.871 T 29-03-2018 IPR033747 Class I PurE SMALA_RS15965 02b08ff1bafadd99033b0cef26dc3743 174 Gene3D G3DSA:3.40.50.7700 1 162 4.9E-74 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 SMALA_RS15965 02b08ff1bafadd99033b0cef26dc3743 174 Pfam PF00731 AIR carboxylase 6 150 2.3E-67 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 SMALA_RS15965 02b08ff1bafadd99033b0cef26dc3743 174 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 6 160 1.9E-65 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 SMALA_RS15965 02b08ff1bafadd99033b0cef26dc3743 174 PIRSF PIRSF001338 1 164 3.2E-70 T 29-03-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 SMALA_RS38335 1f981f3baa743aedc8e21be98ce2e2c5 368 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 7 182 3.8E-45 T 29-03-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain SMALA_RS38335 1f981f3baa743aedc8e21be98ce2e2c5 368 Gene3D G3DSA:3.40.50.300 3 199 1.0E-35 T 29-03-2018 SMALA_RS38335 1f981f3baa743aedc8e21be98ce2e2c5 368 SUPERFAMILY SSF52540 4 192 6.46E-30 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS38335 1f981f3baa743aedc8e21be98ce2e2c5 368 SUPERFAMILY SSF90002 255 345 7.19E-17 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal SMALA_RS38335 1f981f3baa743aedc8e21be98ce2e2c5 368 SMART SM00833 254 345 1.9E-20 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal SMALA_RS38335 1f981f3baa743aedc8e21be98ce2e2c5 368 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 255 345 2.5E-22 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal SMALA_RS38335 1f981f3baa743aedc8e21be98ce2e2c5 368 Gene3D G3DSA:3.30.1220.10 237 346 1.6E-23 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal SMALA_RS07180 50181e62b4b69fae09e3202499585f92 503 SMART SM00429 2 83 7.7E-7 T 29-03-2018 IPR002909 IPT domain SMALA_RS07180 50181e62b4b69fae09e3202499585f92 503 SMART SM00429 421 501 1.5E-4 T 29-03-2018 IPR002909 IPT domain SMALA_RS07180 50181e62b4b69fae09e3202499585f92 503 SMART SM00429 170 249 4.5E-8 T 29-03-2018 IPR002909 IPT domain SMALA_RS07180 50181e62b4b69fae09e3202499585f92 503 SMART SM00429 253 333 7.1E-7 T 29-03-2018 IPR002909 IPT domain SMALA_RS07180 50181e62b4b69fae09e3202499585f92 503 SMART SM00429 87 166 8.9E-8 T 29-03-2018 IPR002909 IPT domain SMALA_RS07180 50181e62b4b69fae09e3202499585f92 503 SMART SM00429 335 419 0.0074 T 29-03-2018 IPR002909 IPT domain SMALA_RS07180 50181e62b4b69fae09e3202499585f92 503 SUPERFAMILY SSF81296 2 82 4.2E-16 T 29-03-2018 IPR014756 Immunoglobulin E-set SMALA_RS07180 50181e62b4b69fae09e3202499585f92 503 SUPERFAMILY SSF81296 252 332 1.01E-16 T 29-03-2018 IPR014756 Immunoglobulin E-set SMALA_RS07180 50181e62b4b69fae09e3202499585f92 503 SUPERFAMILY SSF81296 421 500 2.04E-13 T 29-03-2018 IPR014756 Immunoglobulin E-set SMALA_RS07180 50181e62b4b69fae09e3202499585f92 503 Pfam PF01833 IPT/TIG domain 422 500 6.2E-12 T 29-03-2018 IPR002909 IPT domain SMALA_RS07180 50181e62b4b69fae09e3202499585f92 503 Pfam PF01833 IPT/TIG domain 3 82 6.3E-13 T 29-03-2018 IPR002909 IPT domain SMALA_RS07180 50181e62b4b69fae09e3202499585f92 503 Pfam PF01833 IPT/TIG domain 171 248 3.9E-13 T 29-03-2018 IPR002909 IPT domain SMALA_RS07180 50181e62b4b69fae09e3202499585f92 503 Pfam PF01833 IPT/TIG domain 336 411 1.4E-8 T 29-03-2018 IPR002909 IPT domain SMALA_RS07180 50181e62b4b69fae09e3202499585f92 503 Pfam PF01833 IPT/TIG domain 88 165 3.2E-13 T 29-03-2018 IPR002909 IPT domain SMALA_RS07180 50181e62b4b69fae09e3202499585f92 503 Pfam PF01833 IPT/TIG domain 254 332 5.7E-14 T 29-03-2018 IPR002909 IPT domain SMALA_RS07180 50181e62b4b69fae09e3202499585f92 503 SUPERFAMILY SSF81296 169 248 2.64E-15 T 29-03-2018 IPR014756 Immunoglobulin E-set SMALA_RS07180 50181e62b4b69fae09e3202499585f92 503 Gene3D G3DSA:2.60.40.10 252 330 6.6E-19 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS07180 50181e62b4b69fae09e3202499585f92 503 Gene3D G3DSA:2.60.40.10 168 250 6.9E-20 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS07180 50181e62b4b69fae09e3202499585f92 503 Gene3D G3DSA:2.60.40.10 85 166 3.6E-18 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS07180 50181e62b4b69fae09e3202499585f92 503 SUPERFAMILY SSF81296 335 409 9.04E-12 T 29-03-2018 IPR014756 Immunoglobulin E-set SMALA_RS07180 50181e62b4b69fae09e3202499585f92 503 SUPERFAMILY SSF81296 87 165 1.4E-14 T 29-03-2018 IPR014756 Immunoglobulin E-set SMALA_RS07180 50181e62b4b69fae09e3202499585f92 503 Gene3D G3DSA:2.60.40.10 334 418 6.2E-15 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS07180 50181e62b4b69fae09e3202499585f92 503 Gene3D G3DSA:2.60.40.10 1 82 1.6E-18 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS07180 50181e62b4b69fae09e3202499585f92 503 Gene3D G3DSA:2.60.40.10 420 500 1.9E-14 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS36040 19cdf0b8dac2d83bb19a489930928504 444 SUPERFAMILY SSF56634 100 377 1.44E-40 T 29-03-2018 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMALA_RS36040 19cdf0b8dac2d83bb19a489930928504 444 Gene3D G3DSA:2.40.180.10 46 383 1.7E-47 T 29-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMALA_RS31205 515b55c3a9b92c6c08bf48012ff70217 267 SMART SM00530 12 67 3.1E-12 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS31205 515b55c3a9b92c6c08bf48012ff70217 267 Pfam PF13560 Helix-turn-helix domain 9 70 1.9E-12 T 29-03-2018 SMALA_RS31205 515b55c3a9b92c6c08bf48012ff70217 267 Gene3D G3DSA:1.10.260.40 1 134 1.4E-14 T 29-03-2018 SMALA_RS31205 515b55c3a9b92c6c08bf48012ff70217 267 SUPERFAMILY SSF47413 5 66 1.75E-13 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS13620 562d651cd029eb762cc6923dd77082e5 124 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 4 115 1.4E-25 T 29-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 SMALA_RS13620 562d651cd029eb762cc6923dd77082e5 124 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 3 120 18.984 T 29-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 SMALA_RS13620 562d651cd029eb762cc6923dd77082e5 124 TIGRFAM TIGR00494 crcB: protein CrcB 4 116 2.3E-27 T 29-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 SMALA_RS29975 a63914a8d44e20a7670673c55250c534 370 SMART SM00387 259 369 6.6E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS29975 a63914a8d44e20a7670673c55250c534 370 SUPERFAMILY SSF55874 204 367 5.9E-37 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS29975 a63914a8d44e20a7670673c55250c534 370 Gene3D G3DSA:3.30.565.10 209 369 5.8E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS29975 a63914a8d44e20a7670673c55250c534 370 Gene3D G3DSA:1.10.287.130 140 208 2.7E-16 T 29-03-2018 SMALA_RS29975 a63914a8d44e20a7670673c55250c534 370 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 261 367 2.6E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS29975 a63914a8d44e20a7670673c55250c534 370 Pfam PF00512 His Kinase A (phospho-acceptor) domain 150 214 6.0E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS29975 a63914a8d44e20a7670673c55250c534 370 SMART SM00388 150 214 5.8E-19 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS29975 a63914a8d44e20a7670673c55250c534 370 PRINTS PR00344 Bacterial sensor protein C-terminal signature 353 366 1.6E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS29975 a63914a8d44e20a7670673c55250c534 370 PRINTS PR00344 Bacterial sensor protein C-terminal signature 296 310 1.6E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS29975 a63914a8d44e20a7670673c55250c534 370 PRINTS PR00344 Bacterial sensor protein C-terminal signature 330 348 1.6E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS29975 a63914a8d44e20a7670673c55250c534 370 SUPERFAMILY SSF47384 138 214 6.28E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS11285 6ba89aa9790bfce343655adda6dbaef6 128 SUPERFAMILY SSF54593 10 117 1.75E-8 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS11285 6ba89aa9790bfce343655adda6dbaef6 128 Gene3D G3DSA:3.10.180.10 6 123 2.2E-8 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS40220 a71e12ddc1dab19e94af5db93257eb07 186 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 27 185 9.5E-18 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS40220 a71e12ddc1dab19e94af5db93257eb07 186 Gene3D G3DSA:1.10.10.10 103 186 1.3E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS40220 a71e12ddc1dab19e94af5db93257eb07 186 Pfam PF04542 Sigma-70 region 2 31 100 7.7E-8 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS40220 a71e12ddc1dab19e94af5db93257eb07 186 Pfam PF08281 Sigma-70, region 4 131 181 1.7E-13 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS40220 a71e12ddc1dab19e94af5db93257eb07 186 SUPERFAMILY SSF88659 130 185 2.18E-12 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS40220 a71e12ddc1dab19e94af5db93257eb07 186 SUPERFAMILY SSF88946 8 118 1.02E-21 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS40220 a71e12ddc1dab19e94af5db93257eb07 186 Gene3D G3DSA:1.10.1740.10 7 102 2.3E-20 T 29-03-2018 SMALA_RS31960 06b57e66e62c641f90a6a96910a72364 295 SUPERFAMILY SSF53474 11 292 5.26E-32 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS31960 06b57e66e62c641f90a6a96910a72364 295 Gene3D G3DSA:3.40.50.1820 7 293 7.2E-31 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS31960 06b57e66e62c641f90a6a96910a72364 295 Pfam PF12697 Alpha/beta hydrolase family 22 290 3.7E-18 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS37470 9cbea368789903002aa201b2e8b13a5e 270 Gene3D G3DSA:2.40.30.10 2 86 4.4E-11 T 29-03-2018 SMALA_RS37470 9cbea368789903002aa201b2e8b13a5e 270 PIRSF PIRSF006816 2 264 3.3E-61 T 29-03-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 SMALA_RS37470 9cbea368789903002aa201b2e8b13a5e 270 PRINTS PR00406 Cytochrome B5 reductase signature 84 98 7.8E-9 T 29-03-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 SMALA_RS37470 9cbea368789903002aa201b2e8b13a5e 270 PRINTS PR00406 Cytochrome B5 reductase signature 197 205 7.8E-9 T 29-03-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 SMALA_RS37470 9cbea368789903002aa201b2e8b13a5e 270 PRINTS PR00406 Cytochrome B5 reductase signature 108 127 7.8E-9 T 29-03-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 SMALA_RS37470 9cbea368789903002aa201b2e8b13a5e 270 PRINTS PR00406 Cytochrome B5 reductase signature 146 157 7.8E-9 T 29-03-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 SMALA_RS37470 9cbea368789903002aa201b2e8b13a5e 270 SUPERFAMILY SSF52343 104 244 4.98E-32 T 29-03-2018 SMALA_RS37470 9cbea368789903002aa201b2e8b13a5e 270 Gene3D G3DSA:2.10.240.10 229 261 1.2E-6 T 29-03-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain SMALA_RS37470 9cbea368789903002aa201b2e8b13a5e 270 SUPERFAMILY SSF63380 4 96 1.42E-15 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 SMALA_RS37470 9cbea368789903002aa201b2e8b13a5e 270 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 134 143 2.5E-6 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 SMALA_RS37470 9cbea368789903002aa201b2e8b13a5e 270 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 108 127 2.5E-6 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 SMALA_RS37470 9cbea368789903002aa201b2e8b13a5e 270 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 146 157 2.5E-6 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 SMALA_RS37470 9cbea368789903002aa201b2e8b13a5e 270 Pfam PF00175 Oxidoreductase NAD-binding domain 110 210 6.2E-16 T 29-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 SMALA_RS37470 9cbea368789903002aa201b2e8b13a5e 270 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 229 260 3.3E-6 T 29-03-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain SMALA_RS37470 9cbea368789903002aa201b2e8b13a5e 270 Gene3D G3DSA:3.40.50.80 87 225 1.3E-25 T 29-03-2018 SMALA_RS35470 5a96c4de4e0d8970af8f16fc05d648a0 450 PRINTS PR00732 Glycosyl hydrolase family 4 signature 162 173 1.0E-38 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SMALA_RS35470 5a96c4de4e0d8970af8f16fc05d648a0 450 PRINTS PR00732 Glycosyl hydrolase family 4 signature 73 89 1.0E-38 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SMALA_RS35470 5a96c4de4e0d8970af8f16fc05d648a0 450 PRINTS PR00732 Glycosyl hydrolase family 4 signature 137 154 1.0E-38 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SMALA_RS35470 5a96c4de4e0d8970af8f16fc05d648a0 450 PRINTS PR00732 Glycosyl hydrolase family 4 signature 2 17 1.0E-38 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SMALA_RS35470 5a96c4de4e0d8970af8f16fc05d648a0 450 PRINTS PR00732 Glycosyl hydrolase family 4 signature 108 128 1.0E-38 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SMALA_RS35470 5a96c4de4e0d8970af8f16fc05d648a0 450 PRINTS PR00732 Glycosyl hydrolase family 4 signature 94 107 1.0E-38 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SMALA_RS35470 5a96c4de4e0d8970af8f16fc05d648a0 450 PRINTS PR00732 Glycosyl hydrolase family 4 signature 188 200 1.0E-38 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SMALA_RS35470 5a96c4de4e0d8970af8f16fc05d648a0 450 Pfam PF02056 Family 4 glycosyl hydrolase 5 181 1.2E-43 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SMALA_RS35470 5a96c4de4e0d8970af8f16fc05d648a0 450 SUPERFAMILY SSF51735 1 165 1.5E-45 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS35470 5a96c4de4e0d8970af8f16fc05d648a0 450 ProSitePatterns PS01324 Glycosyl hydrolases family 4 signature. 137 167 - T 29-03-2018 IPR019802 Glycoside hydrolase, family 4, conserved site GO:0004553|GO:0005975 SMALA_RS35470 5a96c4de4e0d8970af8f16fc05d648a0 450 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 192 431 1.1E-42 T 29-03-2018 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 SMALA_RS35470 5a96c4de4e0d8970af8f16fc05d648a0 450 Gene3D G3DSA:3.90.1820.10 1 449 1.4E-131 T 29-03-2018 SMALA_RS35470 5a96c4de4e0d8970af8f16fc05d648a0 450 SUPERFAMILY SSF56327 166 442 2.94E-58 T 29-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 SMALA_RS08015 ab403026bc534883d0a2324f35f1f301 329 SUPERFAMILY SSF55447 225 326 4.19E-27 T 29-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal SMALA_RS08015 ab403026bc534883d0a2324f35f1f301 329 SUPERFAMILY SSF56176 1 219 2.94E-57 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SMALA_RS08015 ab403026bc534883d0a2324f35f1f301 329 Gene3D G3DSA:3.30.390.50 222 329 4.4E-26 T 29-03-2018 SMALA_RS08015 ab403026bc534883d0a2324f35f1f301 329 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 227 323 1.1E-17 T 29-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal SMALA_RS08015 ab403026bc534883d0a2324f35f1f301 329 SMART SM01092 226 324 6.9E-30 T 29-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal SMALA_RS08015 ab403026bc534883d0a2324f35f1f301 329 Gene3D G3DSA:3.30.465.10 57 220 8.3E-34 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SMALA_RS08015 ab403026bc534883d0a2324f35f1f301 329 Gene3D G3DSA:3.30.43.10 1 51 9.3E-19 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 SMALA_RS08015 ab403026bc534883d0a2324f35f1f301 329 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 3 219 2.2E-49 T 29-03-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 SMALA_RS27915 643200fd45d084bc60f645dc90ef2872 238 SUPERFAMILY SSF46785 7 75 2.58E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS27915 643200fd45d084bc60f645dc90ef2872 238 Pfam PF09339 IclR helix-turn-helix domain 10 57 1.2E-8 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMALA_RS27915 643200fd45d084bc60f645dc90ef2872 238 Gene3D G3DSA:1.10.10.10 1 73 8.1E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS27915 643200fd45d084bc60f645dc90ef2872 238 Pfam PF01614 Bacterial transcriptional regulator 125 230 2.3E-17 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal SMALA_RS27915 643200fd45d084bc60f645dc90ef2872 238 SUPERFAMILY SSF55781 62 234 5.1E-35 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS27915 643200fd45d084bc60f645dc90ef2872 238 Gene3D G3DSA:3.30.450.40 74 238 1.7E-35 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS27915 643200fd45d084bc60f645dc90ef2872 238 SMART SM00346 7 93 1.6E-14 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 Gene3D G3DSA:3.40.50.720 2941 3196 1.0E-52 T 29-03-2018 SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 Gene3D G3DSA:3.40.50.720 4710 4975 1.8E-45 T 29-03-2018 SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 SUPERFAMILY SSF51735 2944 3173 3.97E-50 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 SMART SM01294 1673 1740 2.6E-5 T 29-03-2018 SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 SMART SM01294 3231 3298 4.4E-6 T 29-03-2018 SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 SMART SM01294 5025 5092 4.3E-5 T 29-03-2018 SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 Gene3D G3DSA:1.10.1200.10 5005 5104 2.7E-17 T 29-03-2018 SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 SUPERFAMILY SSF51735 4734 4938 1.61E-46 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 SUPERFAMILY SSF51735 2720 2934 2.44E-48 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 SUPERFAMILY SSF53901 34 410 2.88E-104 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 Gene3D G3DSA:3.40.47.10 30 299 1.2E-85 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 Gene3D G3DSA:3.40.47.10 3315 3585 1.2E-88 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 Gene3D G3DSA:3.40.47.10 1769 2033 2.9E-86 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1699 1714 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 SUPERFAMILY SSF47336 1671 1785 1.44E-20 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 SUPERFAMILY SSF55048 2428 2493 3.01E-13 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 SUPERFAMILY SSF51735 1383 1598 1.53E-38 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 SUPERFAMILY SSF51735 4521 4711 2.36E-39 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 SUPERFAMILY SSF55048 698 763 1.83E-14 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 Pfam PF00550 Phosphopantetheine attachment site 1679 1740 2.4E-9 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 Pfam PF00550 Phosphopantetheine attachment site 3232 3298 4.2E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 Pfam PF00550 Phosphopantetheine attachment site 5029 5092 1.5E-8 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 ProSitePatterns PS00012 Phosphopantetheine attachment site. 5051 5066 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 SMART SM00826 939 1104 6.8E-78 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 SMART SM00826 4237 4405 2.8E-80 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 200 216 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 Gene3D G3DSA:3.40.50.720 1379 1768 2.9E-61 T 29-03-2018 SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 SUPERFAMILY SSF47336 3226 3338 3.93E-22 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2149 2266 1.4E-16 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 415 536 8.1E-17 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 3701 3827 3.9E-11 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 Gene3D G3DSA:3.40.366.10 571 708 7.1E-39 T 29-03-2018 SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 Gene3D G3DSA:3.40.366.10 2301 2443 2.2E-41 T 29-03-2018 SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 Gene3D G3DSA:3.40.366.10 3857 4003 1.3E-49 T 29-03-2018 SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 Pfam PF14765 Polyketide synthase dehydratase 939 1218 2.0E-51 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 Pfam PF14765 Polyketide synthase dehydratase 4237 4514 2.4E-58 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 Pfam PF08659 KR domain 1383 1562 3.7E-55 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 Pfam PF08659 KR domain 2948 3125 1.9E-59 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 Pfam PF08659 KR domain 4736 4915 2.2E-55 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 SUPERFAMILY SSF52151 2494 2592 9.16E-68 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 SUPERFAMILY SSF52151 2301 2429 9.16E-68 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 SUPERFAMILY SSF53901 3321 3695 9.37E-108 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 SUPERFAMILY SSF52151 764 862 1.2E-66 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 SUPERFAMILY SSF52151 571 699 1.2E-66 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 37 287 1.9E-91 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1770 2021 3.1E-90 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3323 3573 1.8E-95 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 Gene3D G3DSA:1.10.1200.10 3214 3308 9.2E-20 T 29-03-2018 SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 3486 3502 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 SMART SM00825 Beta-ketoacyl synthase 39 465 7.7E-223 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 SMART SM00825 Beta-ketoacyl synthase 1772 2199 6.9E-219 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 SMART SM00825 Beta-ketoacyl synthase 3325 3751 1.7E-228 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 Gene3D G3DSA:3.10.129.10 4239 4356 5.7E-5 T 29-03-2018 SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 Gene3D G3DSA:3.10.129.10 941 1069 1.4E-7 T 29-03-2018 SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 Gene3D G3DSA:3.40.47.10 302 463 1.7E-61 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 Gene3D G3DSA:3.40.47.10 2036 2197 3.9E-61 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 Gene3D G3DSA:3.40.47.10 3588 3749 5.1E-62 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 Gene3D G3DSA:3.40.366.10 2490 2609 6.4E-27 T 29-03-2018 SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 Gene3D G3DSA:3.40.366.10 4052 4162 4.5E-27 T 29-03-2018 SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 Gene3D G3DSA:3.40.366.10 759 878 9.8E-28 T 29-03-2018 SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 Gene3D G3DSA:3.30.70.250 709 758 2.9E-20 T 29-03-2018 SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 Gene3D G3DSA:3.30.70.250 4004 4051 2.3E-19 T 29-03-2018 SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 Gene3D G3DSA:3.30.70.250 2444 2489 6.3E-19 T 29-03-2018 SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 SUPERFAMILY SSF52151 4056 4150 2.07E-76 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 SUPERFAMILY SSF52151 3860 3992 2.07E-76 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3257 3272 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 Gene3D G3DSA:3.40.50.720 4518 4663 0.086 T 29-03-2018 SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 SUPERFAMILY SSF51735 1226 1371 1.34E-22 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 Pfam PF00698 Acyl transferase domain 572 891 1.6E-89 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 Pfam PF00698 Acyl transferase domain 2302 2621 2.9E-91 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 Pfam PF00698 Acyl transferase domain 3863 4187 8.1E-57 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 SUPERFAMILY SSF47336 5016 5103 2.22E-19 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 SUPERFAMILY SSF55048 3991 4055 3.01E-12 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 574 872 4.5E-124 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2304 2602 4.5E-123 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 3864 4169 4.0E-136 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 SUPERFAMILY SSF53901 1766 2143 6.53E-104 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2029 2146 4.0E-44 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 3581 3698 1.7E-44 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 295 412 2.1E-43 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2948 3127 1.9E-58 T 29-03-2018 SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4736 4916 2.9E-58 T 29-03-2018 SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1383 1563 1.2E-54 T 29-03-2018 SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1934 1950 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 SMART SM00823 Phosphopantetheine attachment site 1672 1744 1.9E-31 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 SMART SM00823 Phosphopantetheine attachment site 3230 3302 1.0E-29 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37820 1759909c75578487eb13e9cf04f30dc6 5180 SMART SM00823 Phosphopantetheine attachment site 5024 5096 8.7E-28 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS38575 c9bbe4c687de1eb0de90d49808339237 776 Gene3D G3DSA:3.40.50.740 332 608 3.6E-41 T 29-03-2018 SMALA_RS38575 c9bbe4c687de1eb0de90d49808339237 776 TIGRFAM TIGR01701 Fdhalpha-like: oxidoreductase alpha (molybdopterin) subunit 22 760 3.7E-268 T 29-03-2018 IPR010046 Oxidoreductase alpha (molybdopterin) subunit GO:0008863|GO:0030151|GO:0051539 SMALA_RS38575 c9bbe4c687de1eb0de90d49808339237 776 SUPERFAMILY SSF50692 639 763 1.74E-17 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain SMALA_RS38575 c9bbe4c687de1eb0de90d49808339237 776 Pfam PF01568 Molydopterin dinucleotide binding domain 647 753 3.9E-9 T 29-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 SMALA_RS38575 c9bbe4c687de1eb0de90d49808339237 776 PIRSF PIRSF000144 2 765 0.0 T 29-03-2018 SMALA_RS38575 c9bbe4c687de1eb0de90d49808339237 776 Gene3D G3DSA:2.40.40.20 636 770 4.4E-23 T 29-03-2018 SMALA_RS38575 c9bbe4c687de1eb0de90d49808339237 776 Pfam PF00384 Molybdopterin oxidoreductase 120 418 5.4E-20 T 29-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS38575 c9bbe4c687de1eb0de90d49808339237 776 SUPERFAMILY SSF53706 58 634 1.83E-128 T 29-03-2018 SMALA_RS38575 c9bbe4c687de1eb0de90d49808339237 776 Gene3D G3DSA:3.40.50.740 121 331 4.1E-37 T 29-03-2018 SMALA_RS22680 78e6e423c2dc9e4aed6d70f762389868 340 SUPERFAMILY SSF55257 14 48 2.35E-24 T 29-03-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMALA_RS22680 78e6e423c2dc9e4aed6d70f762389868 340 SUPERFAMILY SSF55257 170 220 2.35E-24 T 29-03-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMALA_RS22680 78e6e423c2dc9e4aed6d70f762389868 340 Gene3D G3DSA:1.10.150.20 239 322 1.5E-25 T 29-03-2018 SMALA_RS22680 78e6e423c2dc9e4aed6d70f762389868 340 SMART SM00662 18 225 1.3E-94 T 29-03-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMALA_RS22680 78e6e423c2dc9e4aed6d70f762389868 340 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 257 311 2.0E-24 T 29-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMALA_RS22680 78e6e423c2dc9e4aed6d70f762389868 340 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 1 311 34.257 T 29-03-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMALA_RS22680 78e6e423c2dc9e4aed6d70f762389868 340 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 57 149 6.0E-24 T 29-03-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMALA_RS22680 78e6e423c2dc9e4aed6d70f762389868 340 SUPERFAMILY SSF56553 48 169 4.97E-42 T 29-03-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMALA_RS22680 78e6e423c2dc9e4aed6d70f762389868 340 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 19 310 4.8E-115 T 29-03-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMALA_RS22680 78e6e423c2dc9e4aed6d70f762389868 340 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 24 218 2.4E-19 T 29-03-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMALA_RS22680 78e6e423c2dc9e4aed6d70f762389868 340 Gene3D G3DSA:3.30.1360.10 106 221 2.0E-27 T 29-03-2018 SMALA_RS22680 78e6e423c2dc9e4aed6d70f762389868 340 Gene3D G3DSA:3.30.1360.10 3 83 3.4E-17 T 29-03-2018 SMALA_RS22680 78e6e423c2dc9e4aed6d70f762389868 340 SUPERFAMILY SSF47789 247 318 1.83E-23 T 29-03-2018 SMALA_RS22680 78e6e423c2dc9e4aed6d70f762389868 340 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 245 302 8.3E-26 T 29-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMALA_RS15895 03c41387936ddef38d787c7beadfa7d5 303 Gene3D G3DSA:3.30.310.20 7 101 9.9E-5 T 29-03-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal SMALA_RS15895 03c41387936ddef38d787c7beadfa7d5 303 SUPERFAMILY SSF48150 104 283 7.85E-29 T 29-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 SMALA_RS15895 03c41387936ddef38d787c7beadfa7d5 303 Gene3D G3DSA:1.10.340.30 102 264 3.7E-20 T 29-03-2018 SMALA_RS10945 55a3c40b63eb281652f46320d7f4c951 553 SUPERFAMILY SSF49503 203 244 1.22E-31 T 29-03-2018 IPR008972 Cupredoxin SMALA_RS10945 55a3c40b63eb281652f46320d7f4c951 553 SUPERFAMILY SSF49503 302 414 1.22E-31 T 29-03-2018 IPR008972 Cupredoxin SMALA_RS10945 55a3c40b63eb281652f46320d7f4c951 553 Pfam PF00394 Multicopper oxidase 304 405 6.9E-21 T 29-03-2018 IPR001117 Multicopper oxidase, type 1 GO:0055114 SMALA_RS10945 55a3c40b63eb281652f46320d7f4c951 553 Pfam PF07731 Multicopper oxidase 444 547 2.9E-22 T 29-03-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 SMALA_RS10945 55a3c40b63eb281652f46320d7f4c951 553 Gene3D G3DSA:2.60.40.420 200 410 2.6E-41 T 29-03-2018 IPR008972 Cupredoxin SMALA_RS10945 55a3c40b63eb281652f46320d7f4c951 553 Gene3D G3DSA:2.60.40.420 61 198 2.4E-30 T 29-03-2018 IPR008972 Cupredoxin SMALA_RS10945 55a3c40b63eb281652f46320d7f4c951 553 SUPERFAMILY SSF49503 436 548 8.95E-31 T 29-03-2018 IPR008972 Cupredoxin SMALA_RS10945 55a3c40b63eb281652f46320d7f4c951 553 Gene3D G3DSA:2.60.40.420 411 549 1.6E-34 T 29-03-2018 IPR008972 Cupredoxin SMALA_RS10945 55a3c40b63eb281652f46320d7f4c951 553 Pfam PF07732 Multicopper oxidase 99 201 3.5E-31 T 29-03-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 SMALA_RS10945 55a3c40b63eb281652f46320d7f4c951 553 SUPERFAMILY SSF49503 78 223 9.58E-35 T 29-03-2018 IPR008972 Cupredoxin SMALA_RS10945 55a3c40b63eb281652f46320d7f4c951 553 ProSitePatterns PS00080 Multicopper oxidases signature 2. 534 545 - T 29-03-2018 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 SMALA_RS36760 9e1bf1981d162a6a781fb45c0f71b383 1942 Gene3D G3DSA:3.40.366.10 758 877 7.1E-28 T 29-03-2018 SMALA_RS36760 9e1bf1981d162a6a781fb45c0f71b383 1942 Gene3D G3DSA:3.40.47.10 299 460 5.6E-62 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS36760 9e1bf1981d162a6a781fb45c0f71b383 1942 SUPERFAMILY SSF101173 4 34 3.27E-6 T 29-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 SMALA_RS36760 9e1bf1981d162a6a781fb45c0f71b383 1942 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1803 1818 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS36760 9e1bf1981d162a6a781fb45c0f71b383 1942 SUPERFAMILY SSF55048 700 768 1.23E-11 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS36760 9e1bf1981d162a6a781fb45c0f71b383 1942 SUPERFAMILY SSF47336 1769 1858 2.49E-22 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS36760 9e1bf1981d162a6a781fb45c0f71b383 1942 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 577 877 3.9E-113 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS36760 9e1bf1981d162a6a781fb45c0f71b383 1942 Pfam PF14765 Polyketide synthase dehydratase 946 1234 5.1E-54 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS36760 9e1bf1981d162a6a781fb45c0f71b383 1942 SUPERFAMILY SSF51735 1246 1456 1.1E-27 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS36760 9e1bf1981d162a6a781fb45c0f71b383 1942 SUPERFAMILY SSF52151 769 869 6.28E-65 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS36760 9e1bf1981d162a6a781fb45c0f71b383 1942 SUPERFAMILY SSF52151 575 702 6.28E-65 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS36760 9e1bf1981d162a6a781fb45c0f71b383 1942 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 412 536 1.0E-12 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS36760 9e1bf1981d162a6a781fb45c0f71b383 1942 SMART SM00823 Phosphopantetheine attachment site 1776 1848 6.1E-30 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS36760 9e1bf1981d162a6a781fb45c0f71b383 1942 Gene3D G3DSA:3.40.47.10 26 296 2.1E-86 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS36760 9e1bf1981d162a6a781fb45c0f71b383 1942 Pfam PF08990 Erythronolide synthase docking 2 27 3.2E-9 T 29-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 SMALA_RS36760 9e1bf1981d162a6a781fb45c0f71b383 1942 Gene3D G3DSA:3.30.70.250 710 757 5.0E-16 T 29-03-2018 SMALA_RS36760 9e1bf1981d162a6a781fb45c0f71b383 1942 SUPERFAMILY SSF51735 1490 1711 3.54E-42 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS36760 9e1bf1981d162a6a781fb45c0f71b383 1942 SUPERFAMILY SSF53901 31 399 2.63E-105 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS36760 9e1bf1981d162a6a781fb45c0f71b383 1942 Gene3D G3DSA:1.10.1200.10 1732 1857 3.1E-19 T 29-03-2018 SMALA_RS36760 9e1bf1981d162a6a781fb45c0f71b383 1942 Gene3D G3DSA:3.40.50.720 1484 1731 1.2E-45 T 29-03-2018 SMALA_RS36760 9e1bf1981d162a6a781fb45c0f71b383 1942 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1492 1672 4.5E-56 T 29-03-2018 SMALA_RS36760 9e1bf1981d162a6a781fb45c0f71b383 1942 Pfam PF00698 Acyl transferase domain 576 895 1.4E-81 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS36760 9e1bf1981d162a6a781fb45c0f71b383 1942 SMART SM00826 946 1121 7.3E-75 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS36760 9e1bf1981d162a6a781fb45c0f71b383 1942 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 292 409 1.9E-44 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS36760 9e1bf1981d162a6a781fb45c0f71b383 1942 SMART SM00825 Beta-ketoacyl synthase 36 462 1.2E-221 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS36760 9e1bf1981d162a6a781fb45c0f71b383 1942 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 284 2.6E-91 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS36760 9e1bf1981d162a6a781fb45c0f71b383 1942 Pfam PF08659 KR domain 1492 1671 1.1E-56 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS36760 9e1bf1981d162a6a781fb45c0f71b383 1942 Pfam PF00550 Phosphopantetheine attachment site 1779 1844 3.3E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS36760 9e1bf1981d162a6a781fb45c0f71b383 1942 SMART SM01294 1778 1844 0.0012 T 29-03-2018 SMALA_RS36760 9e1bf1981d162a6a781fb45c0f71b383 1942 Gene3D G3DSA:3.40.366.10 573 709 3.0E-41 T 29-03-2018 SMALA_RS36760 9e1bf1981d162a6a781fb45c0f71b383 1942 Gene3D G3DSA:3.10.129.10 948 1079 1.1E-7 T 29-03-2018 SMALA_RS36270 31b1c6e9e35b788066e114d2e7efbf19 279 PIRSF PIRSF001359 1 279 3.4E-70 T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 SMALA_RS36270 31b1c6e9e35b788066e114d2e7efbf19 279 Gene3D G3DSA:3.20.20.70 1 279 1.5E-84 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS36270 31b1c6e9e35b788066e114d2e7efbf19 279 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 2 276 9.5E-68 T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 SMALA_RS36270 31b1c6e9e35b788066e114d2e7efbf19 279 SUPERFAMILY SSF51569 3 276 6.15E-78 T 29-03-2018 SMALA_RS36270 31b1c6e9e35b788066e114d2e7efbf19 279 Pfam PF01116 Fructose-bisphosphate aldolase class-II 6 276 2.2E-77 T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 SMALA_RS21710 c4d11b9b7bef3ac0308cc681a1b0ba67 794 Gene3D G3DSA:2.140.10.10 539 656 5.0E-14 T 29-03-2018 SMALA_RS21710 c4d11b9b7bef3ac0308cc681a1b0ba67 794 Gene3D G3DSA:2.140.10.10 398 538 3.7E-11 T 29-03-2018 SMALA_RS21710 c4d11b9b7bef3ac0308cc681a1b0ba67 794 Pfam PF00069 Protein kinase domain 31 277 2.9E-37 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMALA_RS21710 c4d11b9b7bef3ac0308cc681a1b0ba67 794 Gene3D G3DSA:2.140.10.10 657 792 1.3E-18 T 29-03-2018 SMALA_RS21710 c4d11b9b7bef3ac0308cc681a1b0ba67 794 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 149 161 - T 29-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMALA_RS21710 c4d11b9b7bef3ac0308cc681a1b0ba67 794 SMART SM00564 766 790 580.0 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMALA_RS21710 c4d11b9b7bef3ac0308cc681a1b0ba67 794 SMART SM00564 675 710 75.0 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMALA_RS21710 c4d11b9b7bef3ac0308cc681a1b0ba67 794 SMART SM00564 543 574 5.0 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMALA_RS21710 c4d11b9b7bef3ac0308cc681a1b0ba67 794 SMART SM00564 718 750 0.033 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMALA_RS21710 c4d11b9b7bef3ac0308cc681a1b0ba67 794 SMART SM00564 502 535 20.0 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMALA_RS21710 c4d11b9b7bef3ac0308cc681a1b0ba67 794 SUPERFAMILY SSF56112 28 306 1.89E-63 T 29-03-2018 IPR011009 Protein kinase-like domain SMALA_RS21710 c4d11b9b7bef3ac0308cc681a1b0ba67 794 SUPERFAMILY SSF50969 475 752 2.28E-19 T 29-03-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like SMALA_RS21710 c4d11b9b7bef3ac0308cc681a1b0ba67 794 Pfam PF13360 PQQ-like domain 605 788 1.7E-12 T 29-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat SMALA_RS21710 c4d11b9b7bef3ac0308cc681a1b0ba67 794 Pfam PF13360 PQQ-like domain 437 572 4.2E-12 T 29-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat SMALA_RS21710 c4d11b9b7bef3ac0308cc681a1b0ba67 794 Gene3D G3DSA:1.10.510.10 112 306 5.4E-45 T 29-03-2018 SMALA_RS21710 c4d11b9b7bef3ac0308cc681a1b0ba67 794 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 37 59 - T 29-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 SMALA_RS21710 c4d11b9b7bef3ac0308cc681a1b0ba67 794 SMART SM00220 31 283 3.6E-43 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMALA_RS21710 c4d11b9b7bef3ac0308cc681a1b0ba67 794 Gene3D G3DSA:3.30.200.20 15 111 2.2E-12 T 29-03-2018 SMALA_RS35975 63a346d909257d1df6e083f80a3c3c59 3393 Pfam PF08659 KR domain 1200 1378 1.7E-63 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS35975 63a346d909257d1df6e083f80a3c3c59 3393 Pfam PF08659 KR domain 2952 3130 3.3E-54 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS35975 63a346d909257d1df6e083f80a3c3c59 3393 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3269 3284 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS35975 63a346d909257d1df6e083f80a3c3c59 3393 Gene3D G3DSA:3.30.70.250 710 752 3.0E-18 T 29-03-2018 SMALA_RS35975 63a346d909257d1df6e083f80a3c3c59 3393 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1200 1380 6.0E-64 T 29-03-2018 SMALA_RS35975 63a346d909257d1df6e083f80a3c3c59 3393 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2952 3132 3.3E-62 T 29-03-2018 SMALA_RS35975 63a346d909257d1df6e083f80a3c3c59 3393 SUPERFAMILY SSF55048 2227 2287 2.88E-9 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS35975 63a346d909257d1df6e083f80a3c3c59 3393 Gene3D G3DSA:3.40.366.10 570 709 5.3E-38 T 29-03-2018 SMALA_RS35975 63a346d909257d1df6e083f80a3c3c59 3393 SUPERFAMILY SSF53901 1574 1950 5.61E-103 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS35975 63a346d909257d1df6e083f80a3c3c59 3393 Gene3D G3DSA:1.10.1200.10 3204 3322 1.6E-18 T 29-03-2018 SMALA_RS35975 63a346d909257d1df6e083f80a3c3c59 3393 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2104 2411 6.1E-122 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS35975 63a346d909257d1df6e083f80a3c3c59 3393 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 573 865 6.1E-111 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS35975 63a346d909257d1df6e083f80a3c3c59 3393 SUPERFAMILY SSF47336 3235 3322 4.84E-19 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS35975 63a346d909257d1df6e083f80a3c3c59 3393 SUPERFAMILY SSF47336 1478 1591 3.01E-22 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS35975 63a346d909257d1df6e083f80a3c3c59 3393 SUPERFAMILY SSF53901 31 406 2.18E-100 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS35975 63a346d909257d1df6e083f80a3c3c59 3393 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1740 1756 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS35975 63a346d909257d1df6e083f80a3c3c59 3393 Gene3D G3DSA:3.10.129.10 2480 2604 1.1E-8 T 29-03-2018 SMALA_RS35975 63a346d909257d1df6e083f80a3c3c59 3393 SMART SM00823 Phosphopantetheine attachment site 3242 3314 2.4E-26 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS35975 63a346d909257d1df6e083f80a3c3c59 3393 SMART SM00823 Phosphopantetheine attachment site 1482 1554 4.2E-31 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS35975 63a346d909257d1df6e083f80a3c3c59 3393 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 198 214 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS35975 63a346d909257d1df6e083f80a3c3c59 3393 SUPERFAMILY SSF51735 973 1187 5.51E-40 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS35975 63a346d909257d1df6e083f80a3c3c59 3393 Gene3D G3DSA:3.40.47.10 1576 1839 2.8E-84 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS35975 63a346d909257d1df6e083f80a3c3c59 3393 Gene3D G3DSA:3.40.47.10 27 297 1.5E-83 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS35975 63a346d909257d1df6e083f80a3c3c59 3393 SMART SM00826 2478 2642 1.9E-88 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS35975 63a346d909257d1df6e083f80a3c3c59 3393 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1835 1952 3.9E-43 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS35975 63a346d909257d1df6e083f80a3c3c59 3393 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 293 410 6.2E-42 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS35975 63a346d909257d1df6e083f80a3c3c59 3393 SUPERFAMILY SSF52151 2281 2385 2.46E-72 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS35975 63a346d909257d1df6e083f80a3c3c59 3393 SUPERFAMILY SSF52151 2101 2222 2.46E-72 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS35975 63a346d909257d1df6e083f80a3c3c59 3393 Gene3D G3DSA:3.40.366.10 2275 2398 2.8E-27 T 29-03-2018 SMALA_RS35975 63a346d909257d1df6e083f80a3c3c59 3393 SUPERFAMILY SSF51735 2946 3199 1.09E-46 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS35975 63a346d909257d1df6e083f80a3c3c59 3393 SMART SM01294 1483 1550 1.7E-6 T 29-03-2018 SMALA_RS35975 63a346d909257d1df6e083f80a3c3c59 3393 SMART SM01294 3243 3310 2.6E-4 T 29-03-2018 SMALA_RS35975 63a346d909257d1df6e083f80a3c3c59 3393 SUPERFAMILY SSF51735 1196 1415 5.11E-54 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS35975 63a346d909257d1df6e083f80a3c3c59 3393 Pfam PF14765 Polyketide synthase dehydratase 2478 2749 3.1E-58 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS35975 63a346d909257d1df6e083f80a3c3c59 3393 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1509 1524 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS35975 63a346d909257d1df6e083f80a3c3c59 3393 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 35 285 3.3E-89 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS35975 63a346d909257d1df6e083f80a3c3c59 3393 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1577 1827 6.2E-90 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS35975 63a346d909257d1df6e083f80a3c3c59 3393 Gene3D G3DSA:3.40.366.10 2088 2274 3.2E-56 T 29-03-2018 SMALA_RS35975 63a346d909257d1df6e083f80a3c3c59 3393 Gene3D G3DSA:3.40.366.10 753 872 2.8E-23 T 29-03-2018 SMALA_RS35975 63a346d909257d1df6e083f80a3c3c59 3393 Gene3D G3DSA:3.40.50.720 1192 1452 1.5E-60 T 29-03-2018 SMALA_RS35975 63a346d909257d1df6e083f80a3c3c59 3393 Pfam PF00550 Phosphopantetheine attachment site 3244 3310 8.8E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS35975 63a346d909257d1df6e083f80a3c3c59 3393 Pfam PF00550 Phosphopantetheine attachment site 1485 1550 1.7E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS35975 63a346d909257d1df6e083f80a3c3c59 3393 SUPERFAMILY SSF55048 695 760 5.1E-13 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS35975 63a346d909257d1df6e083f80a3c3c59 3393 Gene3D G3DSA:3.40.50.720 2918 3181 4.0E-47 T 29-03-2018 SMALA_RS35975 63a346d909257d1df6e083f80a3c3c59 3393 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1957 2072 2.6E-15 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS35975 63a346d909257d1df6e083f80a3c3c59 3393 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 415 532 1.5E-12 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS35975 63a346d909257d1df6e083f80a3c3c59 3393 Pfam PF00698 Acyl transferase domain 2103 2428 4.7E-52 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS35975 63a346d909257d1df6e083f80a3c3c59 3393 Pfam PF00698 Acyl transferase domain 571 884 2.5E-84 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS35975 63a346d909257d1df6e083f80a3c3c59 3393 SMART SM00825 Beta-ketoacyl synthase 1579 2005 6.9E-223 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS35975 63a346d909257d1df6e083f80a3c3c59 3393 SMART SM00825 Beta-ketoacyl synthase 37 463 7.7E-209 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS35975 63a346d909257d1df6e083f80a3c3c59 3393 Gene3D G3DSA:3.40.47.10 1842 2003 1.0E-62 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS35975 63a346d909257d1df6e083f80a3c3c59 3393 Gene3D G3DSA:3.40.47.10 300 461 9.6E-57 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS35975 63a346d909257d1df6e083f80a3c3c59 3393 SUPERFAMILY SSF52151 570 696 1.96E-61 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS35975 63a346d909257d1df6e083f80a3c3c59 3393 SUPERFAMILY SSF52151 761 854 1.96E-61 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS35975 63a346d909257d1df6e083f80a3c3c59 3393 SUPERFAMILY SSF51735 2758 2941 4.78E-37 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS35975 63a346d909257d1df6e083f80a3c3c59 3393 Gene3D G3DSA:1.10.1200.10 1470 1575 7.7E-20 T 29-03-2018 SMALA_RS12900 b236b3b4d1d31c98d947aa39c7da497b 993 Pfam PF16640 Bacterial Ig-like domain (group 3) 405 493 9.6E-18 T 29-03-2018 IPR032109 Bacterial Ig-like domain (group 3) SMALA_RS12900 b236b3b4d1d31c98d947aa39c7da497b 993 Pfam PF16640 Bacterial Ig-like domain (group 3) 10 104 4.7E-12 T 29-03-2018 IPR032109 Bacterial Ig-like domain (group 3) SMALA_RS12900 b236b3b4d1d31c98d947aa39c7da497b 993 Pfam PF16640 Bacterial Ig-like domain (group 3) 211 299 2.5E-16 T 29-03-2018 IPR032109 Bacterial Ig-like domain (group 3) SMALA_RS12900 b236b3b4d1d31c98d947aa39c7da497b 993 Pfam PF16640 Bacterial Ig-like domain (group 3) 503 588 2.5E-16 T 29-03-2018 IPR032109 Bacterial Ig-like domain (group 3) SMALA_RS12900 b236b3b4d1d31c98d947aa39c7da497b 993 Pfam PF16640 Bacterial Ig-like domain (group 3) 599 685 5.4E-17 T 29-03-2018 IPR032109 Bacterial Ig-like domain (group 3) SMALA_RS12900 b236b3b4d1d31c98d947aa39c7da497b 993 Pfam PF16640 Bacterial Ig-like domain (group 3) 114 202 6.4E-20 T 29-03-2018 IPR032109 Bacterial Ig-like domain (group 3) SMALA_RS12900 b236b3b4d1d31c98d947aa39c7da497b 993 Pfam PF16640 Bacterial Ig-like domain (group 3) 793 883 4.7E-20 T 29-03-2018 IPR032109 Bacterial Ig-like domain (group 3) SMALA_RS12900 b236b3b4d1d31c98d947aa39c7da497b 993 Pfam PF16640 Bacterial Ig-like domain (group 3) 696 785 3.1E-17 T 29-03-2018 IPR032109 Bacterial Ig-like domain (group 3) SMALA_RS12900 b236b3b4d1d31c98d947aa39c7da497b 993 Pfam PF16640 Bacterial Ig-like domain (group 3) 309 394 6.0E-15 T 29-03-2018 IPR032109 Bacterial Ig-like domain (group 3) SMALA_RS12900 b236b3b4d1d31c98d947aa39c7da497b 993 SUPERFAMILY SSF49373 905 971 5.49E-7 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments SMALA_RS12900 b236b3b4d1d31c98d947aa39c7da497b 993 Gene3D G3DSA:2.60.40.10 198 295 9.5E-4 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS12900 b236b3b4d1d31c98d947aa39c7da497b 993 Gene3D G3DSA:2.60.40.10 685 777 8.9E-4 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS12900 b236b3b4d1d31c98d947aa39c7da497b 993 Gene3D G3DSA:2.60.40.10 96 197 3.3E-5 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS12900 b236b3b4d1d31c98d947aa39c7da497b 993 Gene3D G3DSA:2.60.40.10 296 392 9.3E-5 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS12900 b236b3b4d1d31c98d947aa39c7da497b 993 Gene3D G3DSA:2.60.40.10 1 95 0.061 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS12900 b236b3b4d1d31c98d947aa39c7da497b 993 Gene3D G3DSA:2.60.40.10 778 873 0.0066 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS12900 b236b3b4d1d31c98d947aa39c7da497b 993 Gene3D G3DSA:2.60.40.10 588 683 9.0E-4 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS12900 b236b3b4d1d31c98d947aa39c7da497b 993 Gene3D G3DSA:2.60.40.10 501 587 0.0032 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS12900 b236b3b4d1d31c98d947aa39c7da497b 993 Gene3D G3DSA:2.60.40.10 882 986 6.9E-11 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS12900 b236b3b4d1d31c98d947aa39c7da497b 993 Gene3D G3DSA:3.90.75.10 425 500 0.0012 T 29-03-2018 SMALA_RS40555 55e45c6d07e13ff6d61e69d475a7e2d8 153 Pfam PF14588 YjgF/chorismate_mutase-like, putative endoribonuclease 6 144 8.8E-32 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SMALA_RS40555 55e45c6d07e13ff6d61e69d475a7e2d8 153 SUPERFAMILY SSF55298 1 150 5.18E-40 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SMALA_RS40555 55e45c6d07e13ff6d61e69d475a7e2d8 153 Gene3D G3DSA:3.30.1330.40 1 151 2.1E-24 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SMALA_RS05190 52741e56b1faeea892062d8aea311216 358 Gene3D G3DSA:1.10.3470.10 12 320 5.5E-22 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SMALA_RS05190 52741e56b1faeea892062d8aea311216 358 Pfam PF02653 Branched-chain amino acid transport system / permease component 54 314 8.9E-32 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 SMALA_RS05100 bf303eefafd3dc346cd00f042979b923 219 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 2.5E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS05100 bf303eefafd3dc346cd00f042979b923 219 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 2.5E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS05100 bf303eefafd3dc346cd00f042979b923 219 SUPERFAMILY SSF46689 13 85 1.49E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS05100 bf303eefafd3dc346cd00f042979b923 219 Gene3D G3DSA:1.10.357.10 66 212 1.7E-9 T 29-03-2018 SMALA_RS05100 bf303eefafd3dc346cd00f042979b923 219 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 67 1.1E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS05100 bf303eefafd3dc346cd00f042979b923 219 Gene3D G3DSA:1.10.10.60 11 65 3.2E-15 T 29-03-2018 SMALA_RS00655 b1a5db3592aca3bee7220d337fc8dd98 411 Gene3D G3DSA:1.10.630.10 14 411 5.1E-71 T 29-03-2018 SMALA_RS00655 b1a5db3592aca3bee7220d337fc8dd98 411 SUPERFAMILY SSF48264 23 411 1.57E-92 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS00655 b1a5db3592aca3bee7220d337fc8dd98 411 Pfam PF00067 Cytochrome P450 230 380 1.3E-24 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS00655 b1a5db3592aca3bee7220d337fc8dd98 411 PRINTS PR00385 P450 superfamily signature 284 295 5.7E-8 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS00655 b1a5db3592aca3bee7220d337fc8dd98 411 PRINTS PR00385 P450 superfamily signature 351 360 5.7E-8 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS00655 b1a5db3592aca3bee7220d337fc8dd98 411 PRINTS PR00385 P450 superfamily signature 360 371 5.7E-8 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS00655 b1a5db3592aca3bee7220d337fc8dd98 411 PRINTS PR00385 P450 superfamily signature 247 264 5.7E-8 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS00655 b1a5db3592aca3bee7220d337fc8dd98 411 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 353 362 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMALA_RS00655 b1a5db3592aca3bee7220d337fc8dd98 411 PRINTS PR00359 B-class P450 signature 148 164 2.8E-57 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS00655 b1a5db3592aca3bee7220d337fc8dd98 411 PRINTS PR00359 B-class P450 signature 351 360 2.8E-57 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS00655 b1a5db3592aca3bee7220d337fc8dd98 411 PRINTS PR00359 B-class P450 signature 101 112 2.8E-57 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS00655 b1a5db3592aca3bee7220d337fc8dd98 411 PRINTS PR00359 B-class P450 signature 330 345 2.8E-57 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS00655 b1a5db3592aca3bee7220d337fc8dd98 411 PRINTS PR00359 B-class P450 signature 165 180 2.8E-57 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS00655 b1a5db3592aca3bee7220d337fc8dd98 411 PRINTS PR00359 B-class P450 signature 202 224 2.8E-57 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS00655 b1a5db3592aca3bee7220d337fc8dd98 411 PRINTS PR00359 B-class P450 signature 284 295 2.8E-57 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS00655 b1a5db3592aca3bee7220d337fc8dd98 411 PRINTS PR00359 B-class P450 signature 302 329 2.8E-57 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS00655 b1a5db3592aca3bee7220d337fc8dd98 411 PRINTS PR00359 B-class P450 signature 360 371 2.8E-57 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS09795 1b322b1278fa28f2418293677e94c19d 171 Pfam PF03061 Thioesterase superfamily 62 139 2.6E-17 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 SMALA_RS09795 1b322b1278fa28f2418293677e94c19d 171 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 37 146 1.1E-29 T 29-03-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 SMALA_RS09795 1b322b1278fa28f2418293677e94c19d 171 SUPERFAMILY SSF54637 28 150 1.65E-27 T 29-03-2018 IPR029069 HotDog domain SMALA_RS09795 1b322b1278fa28f2418293677e94c19d 171 Gene3D G3DSA:3.10.129.10 22 155 1.0E-25 T 29-03-2018 SMALA_RS29300 ca347f1091fd1f4c66b63fbeef4d3a33 97 SUPERFAMILY SSF46894 19 82 1.16E-11 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS29300 ca347f1091fd1f4c66b63fbeef4d3a33 97 SMART SM00421 19 76 1.2E-6 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS29300 ca347f1091fd1f4c66b63fbeef4d3a33 97 Pfam PF00196 Bacterial regulatory proteins, luxR family 21 75 2.8E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS29300 ca347f1091fd1f4c66b63fbeef4d3a33 97 Gene3D G3DSA:1.10.10.10 3 86 5.0E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS29300 ca347f1091fd1f4c66b63fbeef4d3a33 97 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 52 64 1.5E-5 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS29300 ca347f1091fd1f4c66b63fbeef4d3a33 97 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 36 52 1.5E-5 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS29300 ca347f1091fd1f4c66b63fbeef4d3a33 97 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 22 36 1.5E-5 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS25310 a73572c9014eb1682399e87c05ef0319 309 SUPERFAMILY SSF53474 46 304 9.92E-55 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS25310 a73572c9014eb1682399e87c05ef0319 309 PRINTS PR00111 Alpha/beta hydrolase fold signature 80 95 1.3E-6 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS25310 a73572c9014eb1682399e87c05ef0319 309 PRINTS PR00111 Alpha/beta hydrolase fold signature 249 263 1.3E-6 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS25310 a73572c9014eb1682399e87c05ef0319 309 PRINTS PR00111 Alpha/beta hydrolase fold signature 124 137 1.3E-6 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS25310 a73572c9014eb1682399e87c05ef0319 309 Pfam PF00561 alpha/beta hydrolase fold 55 292 1.8E-26 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS25310 a73572c9014eb1682399e87c05ef0319 309 Gene3D G3DSA:3.40.50.1820 43 308 5.0E-48 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS22575 e12aa9b0e3befa36e289df0e0a9551d6 74 TIGRFAM TIGR00012 L29: ribosomal protein uL29 9 64 3.8E-22 T 29-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMALA_RS22575 e12aa9b0e3befa36e289df0e0a9551d6 74 SUPERFAMILY SSF46561 5 67 5.49E-24 T 29-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMALA_RS22575 e12aa9b0e3befa36e289df0e0a9551d6 74 Pfam PF00831 Ribosomal L29 protein 8 64 2.8E-26 T 29-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMALA_RS22575 e12aa9b0e3befa36e289df0e0a9551d6 74 ProSitePatterns PS00579 Ribosomal protein L29 signature. 43 57 - T 29-03-2018 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMALA_RS22575 e12aa9b0e3befa36e289df0e0a9551d6 74 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 5 64 17.943 T 29-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMALA_RS22575 e12aa9b0e3befa36e289df0e0a9551d6 74 Gene3D G3DSA:1.10.287.310 5 69 9.9E-28 T 29-03-2018 SMALA_RS01220 9be13797f7c334aafb7138398d27fc45 1124 SUPERFAMILY SSF56059 84 354 1.54E-70 T 29-03-2018 SMALA_RS01220 9be13797f7c334aafb7138398d27fc45 1124 Pfam PF02785 Biotin carboxylase C-terminal domain 339 447 1.1E-34 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SMALA_RS01220 9be13797f7c334aafb7138398d27fc45 1124 SUPERFAMILY SSF51246 333 451 1.26E-37 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 SMALA_RS01220 9be13797f7c334aafb7138398d27fc45 1124 Pfam PF02436 Conserved carboxylase domain 820 1007 1.6E-54 T 29-03-2018 IPR003379 Carboxylase, conserved domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 SMALA_RS01220 9be13797f7c334aafb7138398d27fc45 1124 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SMALA_RS01220 9be13797f7c334aafb7138398d27fc45 1124 Gene3D G3DSA:3.10.600.10 964 1041 4.0E-21 T 29-03-2018 SMALA_RS01220 9be13797f7c334aafb7138398d27fc45 1124 Gene3D G3DSA:3.40.50.20 1 97 4.1E-38 T 29-03-2018 SMALA_RS01220 9be13797f7c334aafb7138398d27fc45 1124 SUPERFAMILY SSF51230 1047 1123 1.28E-15 T 29-03-2018 IPR011053 Single hybrid motif SMALA_RS01220 9be13797f7c334aafb7138398d27fc45 1124 SMART SM00878 339 446 4.6E-55 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SMALA_RS01220 9be13797f7c334aafb7138398d27fc45 1124 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 117 322 3.6E-71 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SMALA_RS01220 9be13797f7c334aafb7138398d27fc45 1124 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 2.9E-40 T 29-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SMALA_RS01220 9be13797f7c334aafb7138398d27fc45 1124 Pfam PF00364 Biotin-requiring enzyme 1065 1123 6.6E-13 T 29-03-2018 IPR000089 Biotin/lipoyl attachment SMALA_RS01220 9be13797f7c334aafb7138398d27fc45 1124 Pfam PF00682 HMGL-like 525 792 2.7E-28 T 29-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 SMALA_RS01220 9be13797f7c334aafb7138398d27fc45 1124 Gene3D G3DSA:3.20.20.70 524 824 8.9E-71 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS01220 9be13797f7c334aafb7138398d27fc45 1124 SUPERFAMILY SSF52440 1 112 6.04E-41 T 29-03-2018 IPR016185 Pre-ATP-grasp domain SMALA_RS01220 9be13797f7c334aafb7138398d27fc45 1124 SUPERFAMILY SSF89000 825 990 1.8E-40 T 29-03-2018 SMALA_RS01220 9be13797f7c334aafb7138398d27fc45 1124 Gene3D G3DSA:2.40.50.100 1054 1124 1.3E-14 T 29-03-2018 SMALA_RS01220 9be13797f7c334aafb7138398d27fc45 1124 Gene3D G3DSA:3.10.600.10 458 523 2.6E-12 T 29-03-2018 SMALA_RS01220 9be13797f7c334aafb7138398d27fc45 1124 TIGRFAM TIGR01235 pyruv_carbox: pyruvate carboxylase 4 1123 0.0 T 29-03-2018 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 SMALA_RS01220 9be13797f7c334aafb7138398d27fc45 1124 Gene3D G3DSA:3.30.470.20 204 449 1.7E-100 T 29-03-2018 SMALA_RS01220 9be13797f7c334aafb7138398d27fc45 1124 Gene3D G3DSA:3.30.1490.20 98 202 7.2E-29 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SMALA_RS01220 9be13797f7c334aafb7138398d27fc45 1124 SUPERFAMILY SSF51569 517 828 5.68E-76 T 29-03-2018 SMALA_RS01220 9be13797f7c334aafb7138398d27fc45 1124 PIRSF PIRSF001594 1 1124 0.0 T 29-03-2018 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 SMALA_RS20880 b35d62f1e73a6078f890d315d3bb7856 201 Gene3D G3DSA:3.40.50.2300 1 126 9.8E-33 T 29-03-2018 SMALA_RS20880 b35d62f1e73a6078f890d315d3bb7856 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 171 183 3.6E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS20880 b35d62f1e73a6078f890d315d3bb7856 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 171 3.6E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS20880 b35d62f1e73a6078f890d315d3bb7856 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 141 155 3.6E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS20880 b35d62f1e73a6078f890d315d3bb7856 201 Pfam PF00196 Bacterial regulatory proteins, luxR family 140 195 1.7E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS20880 b35d62f1e73a6078f890d315d3bb7856 201 SMART SM00421 138 195 2.1E-15 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS20880 b35d62f1e73a6078f890d315d3bb7856 201 SUPERFAMILY SSF46894 131 201 2.18E-17 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS20880 b35d62f1e73a6078f890d315d3bb7856 201 Pfam PF00072 Response regulator receiver domain 4 115 1.9E-23 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS20880 b35d62f1e73a6078f890d315d3bb7856 201 Gene3D G3DSA:1.10.10.10 127 201 7.4E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS20880 b35d62f1e73a6078f890d315d3bb7856 201 SUPERFAMILY SSF52172 2 128 2.13E-30 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS20880 b35d62f1e73a6078f890d315d3bb7856 201 SMART SM00448 2 115 2.5E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS11215 fe861bf31967d4db3253fccdea998a01 822 SMART SM00331 470 693 2.1E-28 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS11215 fe861bf31967d4db3253fccdea998a01 822 SUPERFAMILY SSF81606 484 692 7.59E-6 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS11215 fe861bf31967d4db3253fccdea998a01 822 SUPERFAMILY SSF55874 734 809 3.39E-5 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS11215 fe861bf31967d4db3253fccdea998a01 822 SUPERFAMILY SSF55781 306 345 2.01E-12 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS11215 fe861bf31967d4db3253fccdea998a01 822 SUPERFAMILY SSF55781 378 449 2.01E-12 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS11215 fe861bf31967d4db3253fccdea998a01 822 Gene3D G3DSA:3.30.450.40 258 443 8.8E-29 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS11215 fe861bf31967d4db3253fccdea998a01 822 SUPERFAMILY SSF55785 145 253 2.44E-10 T 29-03-2018 IPR000014 PAS domain SMALA_RS11215 fe861bf31967d4db3253fccdea998a01 822 Gene3D G3DSA:3.30.450.20 20 140 3.3E-9 T 29-03-2018 SMALA_RS11215 fe861bf31967d4db3253fccdea998a01 822 Gene3D G3DSA:3.30.450.20 143 257 2.4E-16 T 29-03-2018 SMALA_RS11215 fe861bf31967d4db3253fccdea998a01 822 SUPERFAMILY SSF55785 24 126 2.58E-7 T 29-03-2018 IPR000014 PAS domain SMALA_RS11215 fe861bf31967d4db3253fccdea998a01 822 Pfam PF08448 PAS fold 147 255 3.3E-18 T 29-03-2018 IPR013656 PAS fold-4 SMALA_RS11215 fe861bf31967d4db3253fccdea998a01 822 Gene3D G3DSA:3.30.565.10 697 821 1.1E-11 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS11215 fe861bf31967d4db3253fccdea998a01 822 SMART SM00065 277 449 0.0087 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS11215 fe861bf31967d4db3253fccdea998a01 822 Pfam PF13581 Histidine kinase-like ATPase domain 707 802 7.7E-7 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS11215 fe861bf31967d4db3253fccdea998a01 822 Pfam PF13426 PAS domain 27 111 0.0036 T 29-03-2018 IPR000014 PAS domain SMALA_RS11215 fe861bf31967d4db3253fccdea998a01 822 Pfam PF01590 GAF domain 355 439 8.6E-7 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS11215 fe861bf31967d4db3253fccdea998a01 822 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 498 693 3.0E-47 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS11215 fe861bf31967d4db3253fccdea998a01 822 Gene3D G3DSA:3.60.40.10 444 696 1.1E-40 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS19865 b7fae422af1537f2b4fa7ec18e437c7d 171 SMART SM00240 97 148 8.7E-14 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 SMALA_RS19865 b7fae422af1537f2b4fa7ec18e437c7d 171 Pfam PF00498 FHA domain 98 163 9.2E-16 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 SMALA_RS19865 b7fae422af1537f2b4fa7ec18e437c7d 171 Gene3D G3DSA:2.60.200.20 46 171 9.7E-28 T 29-03-2018 SMALA_RS19865 b7fae422af1537f2b4fa7ec18e437c7d 171 SUPERFAMILY SSF49879 53 170 1.22E-28 T 29-03-2018 IPR008984 SMAD/FHA domain GO:0005515 SMALA_RS01340 a8c0a768a6cb1678f058f5cb7f9e7105 285 Gene3D G3DSA:3.10.450.40 49 185 2.2E-6 T 29-03-2018 SMALA_RS18645 4b6052fa78a8e76d2f66e0fd917c78d9 353 Gene3D G3DSA:3.90.79.10 28 301 4.8E-29 T 29-03-2018 SMALA_RS18645 4b6052fa78a8e76d2f66e0fd917c78d9 353 SUPERFAMILY SSF55811 223 291 7.58E-12 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMALA_RS18645 4b6052fa78a8e76d2f66e0fd917c78d9 353 SUPERFAMILY SSF55811 167 178 7.58E-12 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMALA_RS18645 4b6052fa78a8e76d2f66e0fd917c78d9 353 SUPERFAMILY SSF55811 105 137 7.58E-12 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMALA_RS35085 3a708bc4ad277ea536f2e32a49dc3ca4 312 Gene3D G3DSA:1.10.1740.10 61 148 3.0E-16 T 29-03-2018 SMALA_RS35085 3a708bc4ad277ea536f2e32a49dc3ca4 312 SUPERFAMILY SSF88659 172 238 1.42E-9 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS35085 3a708bc4ad277ea536f2e32a49dc3ca4 312 Gene3D G3DSA:1.10.10.10 162 247 2.5E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS35085 3a708bc4ad277ea536f2e32a49dc3ca4 312 Pfam PF04542 Sigma-70 region 2 85 147 6.9E-11 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS35085 3a708bc4ad277ea536f2e32a49dc3ca4 312 SUPERFAMILY SSF88946 66 162 1.18E-14 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS35085 3a708bc4ad277ea536f2e32a49dc3ca4 312 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 84 238 2.6E-16 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS09630 c9d728f1766317486760762dc20ae863 274 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 42 254 3.3E-33 T 29-03-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type SMALA_RS09630 c9d728f1766317486760762dc20ae863 274 SUPERFAMILY SSF109854 31 184 5.13E-38 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes SMALA_RS09630 c9d728f1766317486760762dc20ae863 274 SUPERFAMILY SSF55718 188 272 9.18E-10 T 29-03-2018 IPR003033 SCP2 sterol-binding domain SMALA_RS09630 c9d728f1766317486760762dc20ae863 274 Gene3D G3DSA:1.20.120.450 30 183 7.9E-18 T 29-03-2018 SMALA_RS09630 c9d728f1766317486760762dc20ae863 274 Pfam PF07398 MDMPI C-terminal domain 186 265 9.0E-8 T 29-03-2018 IPR010872 MDMPI C-terminal SMALA_RS09630 c9d728f1766317486760762dc20ae863 274 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 43 179 7.0E-23 T 29-03-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 SMALA_RS17595 8871a6b9555765834d7ab18906cda4d9 336 Pfam PF00107 Zinc-binding dehydrogenase 180 300 4.5E-17 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMALA_RS17595 8871a6b9555765834d7ab18906cda4d9 336 SUPERFAMILY SSF51735 145 304 8.82E-38 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS17595 8871a6b9555765834d7ab18906cda4d9 336 SMART SM00829 13 334 2.8E-6 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS17595 8871a6b9555765834d7ab18906cda4d9 336 Gene3D G3DSA:3.40.50.720 169 306 2.4E-23 T 29-03-2018 SMALA_RS17595 8871a6b9555765834d7ab18906cda4d9 336 Gene3D G3DSA:3.90.180.10 1 168 2.8E-40 T 29-03-2018 SMALA_RS17595 8871a6b9555765834d7ab18906cda4d9 336 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 61 75 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 SMALA_RS17595 8871a6b9555765834d7ab18906cda4d9 336 SUPERFAMILY SSF50129 1 185 2.99E-36 T 29-03-2018 IPR011032 GroES-like SMALA_RS17595 8871a6b9555765834d7ab18906cda4d9 336 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 131 2.4E-21 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS34065 655823f63a2f77ba937c48e01df78dfa 197 SUPERFAMILY SSF48498 71 187 5.19E-24 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS34065 655823f63a2f77ba937c48e01df78dfa 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 58 2.5E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS34065 655823f63a2f77ba937c48e01df78dfa 197 SUPERFAMILY SSF46689 3 67 5.13E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS34065 655823f63a2f77ba937c48e01df78dfa 197 Pfam PF16859 Bacterial transcriptional repressor C-terminal 71 181 1.3E-26 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS34065 655823f63a2f77ba937c48e01df78dfa 197 Gene3D G3DSA:1.10.10.60 1 57 4.3E-11 T 29-03-2018 SMALA_RS34065 655823f63a2f77ba937c48e01df78dfa 197 Gene3D G3DSA:1.10.357.10 58 192 2.8E-19 T 29-03-2018 SMALA_RS19600 3c61d162736db7e3e6536e63a2d48faf 343 SUPERFAMILY SSF51419 10 176 1.14E-15 T 29-03-2018 IPR029066 PLP-binding barrel SMALA_RS19600 3c61d162736db7e3e6536e63a2d48faf 343 Gene3D G3DSA:3.20.20.10 1 183 4.5E-9 T 29-03-2018 IPR029066 PLP-binding barrel SMALA_RS19600 3c61d162736db7e3e6536e63a2d48faf 343 Gene3D G3DSA:2.40.37.10 196 341 4.4E-16 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 SMALA_RS19600 3c61d162736db7e3e6536e63a2d48faf 343 Pfam PF01168 Alanine racemase, N-terminal domain 11 153 7.7E-14 T 29-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SMALA_RS13415 b0db5c2985477ce7225d26431af483b2 366 SUPERFAMILY SSF82689 213 306 1.83E-10 T 29-03-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 SMALA_RS13415 b0db5c2985477ce7225d26431af483b2 366 SUPERFAMILY SSF82861 86 147 2.62E-9 T 29-03-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 SMALA_RS13415 b0db5c2985477ce7225d26431af483b2 366 SUPERFAMILY SSF50182 149 206 2.81E-9 T 29-03-2018 IPR010920 LSM domain SMALA_RS13415 b0db5c2985477ce7225d26431af483b2 366 Gene3D G3DSA:2.30.30.60 164 212 2.2E-9 T 29-03-2018 SMALA_RS13415 b0db5c2985477ce7225d26431af483b2 366 Pfam PF00924 Mechanosensitive ion channel 107 305 5.2E-36 T 29-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 SMALA_RS13415 b0db5c2985477ce7225d26431af483b2 366 Gene3D G3DSA:3.30.70.100 213 307 2.3E-10 T 29-03-2018 SMALA_RS23170 86aa64fa0a7a02948a73286d36fab0d6 974 PRINTS PR00364 Disease resistance protein signature 471 485 1.5E-8 T 29-03-2018 SMALA_RS23170 86aa64fa0a7a02948a73286d36fab0d6 974 PRINTS PR00364 Disease resistance protein signature 309 324 1.5E-8 T 29-03-2018 SMALA_RS23170 86aa64fa0a7a02948a73286d36fab0d6 974 PRINTS PR00364 Disease resistance protein signature 386 400 1.5E-8 T 29-03-2018 SMALA_RS23170 86aa64fa0a7a02948a73286d36fab0d6 974 Gene3D G3DSA:1.10.10.10 3 104 2.5E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS23170 86aa64fa0a7a02948a73286d36fab0d6 974 Pfam PF13424 Tetratricopeptide repeat 776 834 3.4E-11 T 29-03-2018 SMALA_RS23170 86aa64fa0a7a02948a73286d36fab0d6 974 Pfam PF03704 Bacterial transcriptional activator domain 108 252 1.8E-42 T 29-03-2018 IPR005158 Bacterial transcriptional activator domain SMALA_RS23170 86aa64fa0a7a02948a73286d36fab0d6 974 SUPERFAMILY SSF48452 741 954 6.24E-23 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS23170 86aa64fa0a7a02948a73286d36fab0d6 974 SUPERFAMILY SSF48452 107 268 2.01E-32 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS23170 86aa64fa0a7a02948a73286d36fab0d6 974 SMART SM00028 763 797 390.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS23170 86aa64fa0a7a02948a73286d36fab0d6 974 SMART SM00028 923 956 0.38 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS23170 86aa64fa0a7a02948a73286d36fab0d6 974 SMART SM00028 844 877 26.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS23170 86aa64fa0a7a02948a73286d36fab0d6 974 SMART SM00028 884 917 76.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS23170 86aa64fa0a7a02948a73286d36fab0d6 974 SMART SM00028 804 837 3.3 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS23170 86aa64fa0a7a02948a73286d36fab0d6 974 SMART SM00028 723 756 310.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS23170 86aa64fa0a7a02948a73286d36fab0d6 974 Gene3D G3DSA:3.30.70.100 688 762 0.11 T 29-03-2018 SMALA_RS23170 86aa64fa0a7a02948a73286d36fab0d6 974 Pfam PF00486 Transcriptional regulatory protein, C terminal 34 99 2.0E-7 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS23170 86aa64fa0a7a02948a73286d36fab0d6 974 Gene3D G3DSA:3.40.50.300 274 428 1.1E-15 T 29-03-2018 SMALA_RS23170 86aa64fa0a7a02948a73286d36fab0d6 974 SUPERFAMILY SSF52540 276 538 1.47E-25 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS23170 86aa64fa0a7a02948a73286d36fab0d6 974 SMART SM00862 27 101 1.4E-7 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS23170 86aa64fa0a7a02948a73286d36fab0d6 974 Gene3D G3DSA:1.25.40.10 763 867 1.0E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS23170 86aa64fa0a7a02948a73286d36fab0d6 974 Gene3D G3DSA:1.25.40.10 106 271 6.2E-22 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS23170 86aa64fa0a7a02948a73286d36fab0d6 974 SMART SM01043 108 252 1.4E-49 T 29-03-2018 IPR005158 Bacterial transcriptional activator domain SMALA_RS23170 86aa64fa0a7a02948a73286d36fab0d6 974 Gene3D G3DSA:1.25.40.10 868 961 6.1E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS23170 86aa64fa0a7a02948a73286d36fab0d6 974 Pfam PF00931 NB-ARC domain 292 531 5.5E-14 T 29-03-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207 SMALA_RS23170 86aa64fa0a7a02948a73286d36fab0d6 974 SUPERFAMILY SSF46894 14 89 8.79E-12 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS24000 042ef9df41414866a300178954ce24ae 400 Gene3D G3DSA:3.30.70.890 222 399 2.0E-50 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain SMALA_RS24000 042ef9df41414866a300178954ce24ae 400 Hamap MF_00246 Galactokinase [galK]. 28 399 40.599 T 29-03-2018 IPR022963 Galactokinase, bacterial GO:0004335|GO:0006012 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 SMALA_RS24000 042ef9df41414866a300178954ce24ae 400 PRINTS PR00959 Mevalonate kinase family signature 346 363 3.5E-41 T 29-03-2018 SMALA_RS24000 042ef9df41414866a300178954ce24ae 400 PRINTS PR00959 Mevalonate kinase family signature 28 52 3.5E-41 T 29-03-2018 SMALA_RS24000 042ef9df41414866a300178954ce24ae 400 PRINTS PR00959 Mevalonate kinase family signature 174 193 3.5E-41 T 29-03-2018 SMALA_RS24000 042ef9df41414866a300178954ce24ae 400 PRINTS PR00959 Mevalonate kinase family signature 131 153 3.5E-41 T 29-03-2018 SMALA_RS24000 042ef9df41414866a300178954ce24ae 400 Pfam PF10509 Galactokinase galactose-binding signature 14 61 2.6E-21 T 29-03-2018 IPR019539 Galactokinase galactose-binding domain GO:0005534 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 SMALA_RS24000 042ef9df41414866a300178954ce24ae 400 ProSitePatterns PS00106 Galactokinase signature. 30 41 - T 29-03-2018 IPR019741 Galactokinase, conserved site KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 SMALA_RS24000 042ef9df41414866a300178954ce24ae 400 Pfam PF08544 GHMP kinases C terminal 300 378 8.9E-11 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain SMALA_RS24000 042ef9df41414866a300178954ce24ae 400 PRINTS PR00473 Galactokinase signature 283 297 6.2E-24 T 29-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 SMALA_RS24000 042ef9df41414866a300178954ce24ae 400 PRINTS PR00473 Galactokinase signature 30 48 6.2E-24 T 29-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 SMALA_RS24000 042ef9df41414866a300178954ce24ae 400 PRINTS PR00473 Galactokinase signature 124 142 6.2E-24 T 29-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 SMALA_RS24000 042ef9df41414866a300178954ce24ae 400 PRINTS PR00473 Galactokinase signature 101 112 6.2E-24 T 29-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 SMALA_RS24000 042ef9df41414866a300178954ce24ae 400 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 133 144 - T 29-03-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 SMALA_RS24000 042ef9df41414866a300178954ce24ae 400 Pfam PF00288 GHMP kinases N terminal domain 127 192 8.6E-18 T 29-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 SMALA_RS24000 042ef9df41414866a300178954ce24ae 400 TIGRFAM TIGR00131 gal_kin: galactokinase 11 378 3.9E-89 T 29-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 SMALA_RS24000 042ef9df41414866a300178954ce24ae 400 SUPERFAMILY SSF55060 219 398 5.55E-45 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain SMALA_RS24000 042ef9df41414866a300178954ce24ae 400 SUPERFAMILY SSF54211 10 214 2.73E-59 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SMALA_RS24000 042ef9df41414866a300178954ce24ae 400 Gene3D G3DSA:3.30.230.10 8 221 1.7E-59 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SMALA_RS24000 042ef9df41414866a300178954ce24ae 400 PIRSF PIRSF000530 3 400 4.9E-119 T 29-03-2018 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 SMALA_RS23910 fde56fc2b1261cf0d3618e46c7a0b42f 310 SUPERFAMILY SSF103481 42 136 9.94E-12 T 29-03-2018 SMALA_RS23910 fde56fc2b1261cf0d3618e46c7a0b42f 310 Pfam PF00892 EamA-like transporter family 174 307 8.5E-9 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SMALA_RS23910 fde56fc2b1261cf0d3618e46c7a0b42f 310 SUPERFAMILY SSF103481 221 308 3.27E-9 T 29-03-2018 SMALA_RS34260 6dd2f24bd7acd2a6fb390a0cfb1c334c 618 Pfam PF03663 Glycosyl hydrolase family 76 285 614 2.9E-41 T 29-03-2018 IPR005198 Glycoside hydrolase, family 76 KEGG: 00052+3.2.1.10|KEGG: 00500+3.2.1.10 SMALA_RS34260 6dd2f24bd7acd2a6fb390a0cfb1c334c 618 Gene3D G3DSA:1.50.10.20 281 615 2.7E-55 T 29-03-2018 SMALA_RS34260 6dd2f24bd7acd2a6fb390a0cfb1c334c 618 SUPERFAMILY SSF48208 299 602 1.19E-40 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 SMALA_RS34260 6dd2f24bd7acd2a6fb390a0cfb1c334c 618 Gene3D G3DSA:2.120.10.10 48 239 6.2E-4 T 29-03-2018 SMALA_RS02585 72effe1adb6c34beb7dcec43be5b8c99 243 ProSitePatterns PS00012 Phosphopantetheine attachment site. 117 132 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS02585 72effe1adb6c34beb7dcec43be5b8c99 243 SUPERFAMILY SSF47336 82 172 7.2E-23 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS02585 72effe1adb6c34beb7dcec43be5b8c99 243 Gene3D G3DSA:1.20.1270.130 163 203 0.18 T 29-03-2018 SMALA_RS02585 72effe1adb6c34beb7dcec43be5b8c99 243 Pfam PF00550 Phosphopantetheine attachment site 92 158 3.4E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS02585 72effe1adb6c34beb7dcec43be5b8c99 243 Gene3D G3DSA:1.10.1200.10 73 162 9.1E-22 T 29-03-2018 SMALA_RS02585 72effe1adb6c34beb7dcec43be5b8c99 243 SMART SM00823 Phosphopantetheine attachment site 90 162 4.7E-31 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS02585 72effe1adb6c34beb7dcec43be5b8c99 243 SMART SM01294 91 158 5.4E-6 T 29-03-2018 SMALA_RS09575 0e822bea815785666c08c290bbb17850 400 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 3 400 40.907 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMALA_RS09575 0e822bea815785666c08c290bbb17850 400 Pfam PF00162 Phosphoglycerate kinase 4 390 2.2E-147 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMALA_RS09575 0e822bea815785666c08c290bbb17850 400 SUPERFAMILY SSF53748 2 400 4.24E-143 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMALA_RS09575 0e822bea815785666c08c290bbb17850 400 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 13 23 - T 29-03-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMALA_RS09575 0e822bea815785666c08c290bbb17850 400 PRINTS PR00477 Phosphoglycerate kinase family signature 8 24 3.4E-81 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMALA_RS09575 0e822bea815785666c08c290bbb17850 400 PRINTS PR00477 Phosphoglycerate kinase family signature 29 51 3.4E-81 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMALA_RS09575 0e822bea815785666c08c290bbb17850 400 PRINTS PR00477 Phosphoglycerate kinase family signature 139 161 3.4E-81 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMALA_RS09575 0e822bea815785666c08c290bbb17850 400 PRINTS PR00477 Phosphoglycerate kinase family signature 107 122 3.4E-81 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMALA_RS09575 0e822bea815785666c08c290bbb17850 400 PRINTS PR00477 Phosphoglycerate kinase family signature 192 211 3.4E-81 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMALA_RS09575 0e822bea815785666c08c290bbb17850 400 PRINTS PR00477 Phosphoglycerate kinase family signature 376 393 3.4E-81 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMALA_RS09575 0e822bea815785666c08c290bbb17850 400 PRINTS PR00477 Phosphoglycerate kinase family signature 169 191 3.4E-81 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMALA_RS09575 0e822bea815785666c08c290bbb17850 400 PRINTS PR00477 Phosphoglycerate kinase family signature 319 344 3.4E-81 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMALA_RS09575 0e822bea815785666c08c290bbb17850 400 PRINTS PR00477 Phosphoglycerate kinase family signature 352 363 3.4E-81 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMALA_RS09575 0e822bea815785666c08c290bbb17850 400 Gene3D G3DSA:3.40.50.1260 181 388 6.9E-79 T 29-03-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMALA_RS09575 0e822bea815785666c08c290bbb17850 400 Gene3D G3DSA:3.40.50.1260 1 180 3.9E-68 T 29-03-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMALA_RS09575 0e822bea815785666c08c290bbb17850 400 PIRSF PIRSF000724 1 400 4.7E-134 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMALA_RS30690 086b2c5e067579277870be0d1a8d9634 214 Gene3D G3DSA:1.10.3720.10 2 214 1.6E-32 T 29-03-2018 SMALA_RS30690 086b2c5e067579277870be0d1a8d9634 214 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 30 209 3.0E-12 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS30690 086b2c5e067579277870be0d1a8d9634 214 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 10 105 2.8E-17 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 SMALA_RS30690 086b2c5e067579277870be0d1a8d9634 214 SUPERFAMILY SSF161098 11 196 2.4E-34 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS05625 4148c77a1d26ce4657db624ec8866e49 281 SUPERFAMILY SSF53850 93 274 3.26E-19 T 29-03-2018 SMALA_RS05625 4148c77a1d26ce4657db624ec8866e49 281 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 1.0E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS05625 4148c77a1d26ce4657db624ec8866e49 281 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 1.0E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS05625 4148c77a1d26ce4657db624ec8866e49 281 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 1.0E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS05625 4148c77a1d26ce4657db624ec8866e49 281 Gene3D G3DSA:3.40.190.10 177 201 1.9E-5 T 29-03-2018 SMALA_RS05625 4148c77a1d26ce4657db624ec8866e49 281 Pfam PF03466 LysR substrate binding domain 91 194 1.5E-12 T 29-03-2018 IPR005119 LysR, substrate-binding SMALA_RS05625 4148c77a1d26ce4657db624ec8866e49 281 Gene3D G3DSA:1.10.10.10 2 86 9.7E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS05625 4148c77a1d26ce4657db624ec8866e49 281 Gene3D G3DSA:3.40.190.10 91 176 9.9E-15 T 29-03-2018 SMALA_RS05625 4148c77a1d26ce4657db624ec8866e49 281 Gene3D G3DSA:3.40.190.10 202 251 0.002 T 29-03-2018 SMALA_RS05625 4148c77a1d26ce4657db624ec8866e49 281 SUPERFAMILY SSF46785 5 87 1.63E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS05625 4148c77a1d26ce4657db624ec8866e49 281 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 65 2.4E-21 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS05340 5a6d70c172011f58fcf20b50f4e01164 160 SUPERFAMILY SSF46785 6 80 3.75E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS05340 5a6d70c172011f58fcf20b50f4e01164 160 ProSitePatterns PS00519 AsnC-type HTH domain signature. 25 51 - T 29-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site SMALA_RS05340 5a6d70c172011f58fcf20b50f4e01164 160 SMART SM00344 7 113 1.3E-24 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 SMALA_RS05340 5a6d70c172011f58fcf20b50f4e01164 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 7 23 4.7E-10 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMALA_RS05340 5a6d70c172011f58fcf20b50f4e01164 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 23 34 4.7E-10 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMALA_RS05340 5a6d70c172011f58fcf20b50f4e01164 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 34 53 4.7E-10 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMALA_RS05340 5a6d70c172011f58fcf20b50f4e01164 160 Pfam PF13404 AsnC-type helix-turn-helix domain 7 48 6.3E-14 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMALA_RS05340 5a6d70c172011f58fcf20b50f4e01164 160 Gene3D G3DSA:3.30.70.920 60 153 4.4E-22 T 29-03-2018 SMALA_RS05340 5a6d70c172011f58fcf20b50f4e01164 160 SUPERFAMILY SSF54909 68 152 6.17E-18 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel SMALA_RS05340 5a6d70c172011f58fcf20b50f4e01164 160 Gene3D G3DSA:1.10.10.10 1 56 1.1E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS05340 5a6d70c172011f58fcf20b50f4e01164 160 Pfam PF01037 Lrp/AsnC ligand binding domain 75 143 1.7E-15 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain SMALA_RS36230 29e6642ff2dfce851a9cee381dd9780b 202 Gene3D G3DSA:1.10.10.10 118 192 6.2E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS36230 29e6642ff2dfce851a9cee381dd9780b 202 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 7 107 5.7E-8 T 29-03-2018 IPR000014 PAS domain SMALA_RS36230 29e6642ff2dfce851a9cee381dd9780b 202 SMART SM00421 124 181 3.5E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS36230 29e6642ff2dfce851a9cee381dd9780b 202 Gene3D G3DSA:3.30.450.20 3 117 1.1E-11 T 29-03-2018 SMALA_RS36230 29e6642ff2dfce851a9cee381dd9780b 202 SUPERFAMILY SSF46894 120 187 1.94E-12 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS36230 29e6642ff2dfce851a9cee381dd9780b 202 Pfam PF00989 PAS fold 26 108 9.3E-6 T 29-03-2018 IPR013767 PAS fold GO:0006355 SMALA_RS36230 29e6642ff2dfce851a9cee381dd9780b 202 Pfam PF00196 Bacterial regulatory proteins, luxR family 126 180 1.9E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS36230 29e6642ff2dfce851a9cee381dd9780b 202 SUPERFAMILY SSF55785 6 104 9.95E-10 T 29-03-2018 IPR000014 PAS domain SMALA_RS35995 04c888a97ddca047927d3495f6876f63 198 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 6 177 1.5E-54 T 29-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 SMALA_RS35995 04c888a97ddca047927d3495f6876f63 198 Gene3D G3DSA:2.60.120.10 1 191 2.3E-59 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SMALA_RS35995 04c888a97ddca047927d3495f6876f63 198 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 1 178 4.0E-61 T 29-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 SMALA_RS35995 04c888a97ddca047927d3495f6876f63 198 SUPERFAMILY SSF51182 1 194 1.88E-65 T 29-03-2018 IPR011051 RmlC-like cupin domain SMALA_RS22670 5bdb6e843d159f125f4fceb9cac921fa 134 ProSitePatterns PS00054 Ribosomal protein S11 signature. 102 124 - T 29-03-2018 IPR018102 Ribosomal S11, conserved site SMALA_RS22670 5bdb6e843d159f125f4fceb9cac921fa 134 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 15 131 1.7E-59 T 29-03-2018 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS22670 5bdb6e843d159f125f4fceb9cac921fa 134 SUPERFAMILY SSF53137 19 134 4.8E-50 T 29-03-2018 SMALA_RS22670 5bdb6e843d159f125f4fceb9cac921fa 134 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 4 134 34.428 T 29-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 SMALA_RS22670 5bdb6e843d159f125f4fceb9cac921fa 134 Pfam PF00411 Ribosomal protein S11 24 133 1.4E-48 T 29-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 SMALA_RS22670 5bdb6e843d159f125f4fceb9cac921fa 134 PIRSF PIRSF002131 4 134 4.9E-54 T 29-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 SMALA_RS22670 5bdb6e843d159f125f4fceb9cac921fa 134 Gene3D G3DSA:3.30.420.80 10 134 9.7E-48 T 29-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 SMALA_RS02360 4f48b94c6b8951dada4c78fed7cf7aea 2212 Pfam PF08659 KR domain 1776 1954 6.1E-58 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS02360 4f48b94c6b8951dada4c78fed7cf7aea 2212 Gene3D G3DSA:3.90.180.10 1429 1596 1.9E-39 T 29-03-2018 SMALA_RS02360 4f48b94c6b8951dada4c78fed7cf7aea 2212 SUPERFAMILY SSF51735 1560 1737 1.92E-39 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS02360 4f48b94c6b8951dada4c78fed7cf7aea 2212 SMART SM00829 1461 1766 2.5E-174 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS02360 4f48b94c6b8951dada4c78fed7cf7aea 2212 Pfam PF14765 Polyketide synthase dehydratase 980 1256 1.8E-53 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS02360 4f48b94c6b8951dada4c78fed7cf7aea 2212 Gene3D G3DSA:3.40.366.10 598 791 1.1E-50 T 29-03-2018 SMALA_RS02360 4f48b94c6b8951dada4c78fed7cf7aea 2212 Gene3D G3DSA:3.40.366.10 792 919 1.8E-23 T 29-03-2018 SMALA_RS02360 4f48b94c6b8951dada4c78fed7cf7aea 2212 Pfam PF13602 Zinc-binding dehydrogenase 1639 1765 1.6E-18 T 29-03-2018 SMALA_RS02360 4f48b94c6b8951dada4c78fed7cf7aea 2212 Pfam PF00698 Acyl transferase domain 614 931 1.9E-85 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS02360 4f48b94c6b8951dada4c78fed7cf7aea 2212 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2087 2102 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS02360 4f48b94c6b8951dada4c78fed7cf7aea 2212 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 615 913 7.2E-103 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS02360 4f48b94c6b8951dada4c78fed7cf7aea 2212 Gene3D G3DSA:3.90.180.10 1701 1768 0.21 T 29-03-2018 SMALA_RS02360 4f48b94c6b8951dada4c78fed7cf7aea 2212 SUPERFAMILY SSF52151 612 740 9.42E-67 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS02360 4f48b94c6b8951dada4c78fed7cf7aea 2212 SUPERFAMILY SSF52151 805 899 9.42E-67 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS02360 4f48b94c6b8951dada4c78fed7cf7aea 2212 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 412 573 1.1E-11 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS02360 4f48b94c6b8951dada4c78fed7cf7aea 2212 Gene3D G3DSA:3.40.50.720 1769 2029 2.1E-51 T 29-03-2018 SMALA_RS02360 4f48b94c6b8951dada4c78fed7cf7aea 2212 SMART SM01294 2061 2128 5.8E-5 T 29-03-2018 SMALA_RS02360 4f48b94c6b8951dada4c78fed7cf7aea 2212 Gene3D G3DSA:3.40.50.720 1597 1700 1.1E-14 T 29-03-2018 SMALA_RS02360 4f48b94c6b8951dada4c78fed7cf7aea 2212 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 1588 1609 - T 29-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 SMALA_RS02360 4f48b94c6b8951dada4c78fed7cf7aea 2212 Pfam PF00550 Phosphopantetheine attachment site 2063 2128 6.8E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS02360 4f48b94c6b8951dada4c78fed7cf7aea 2212 SUPERFAMILY SSF53901 34 407 4.4E-102 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS02360 4f48b94c6b8951dada4c78fed7cf7aea 2212 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 294 409 1.1E-45 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS02360 4f48b94c6b8951dada4c78fed7cf7aea 2212 Gene3D G3DSA:1.10.1200.10 2030 2141 8.0E-19 T 29-03-2018 SMALA_RS02360 4f48b94c6b8951dada4c78fed7cf7aea 2212 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1776 1956 1.3E-59 T 29-03-2018 SMALA_RS02360 4f48b94c6b8951dada4c78fed7cf7aea 2212 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 36 286 2.5E-86 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS02360 4f48b94c6b8951dada4c78fed7cf7aea 2212 Gene3D G3DSA:3.40.47.10 301 460 3.3E-64 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS02360 4f48b94c6b8951dada4c78fed7cf7aea 2212 SUPERFAMILY SSF55048 739 799 6.54E-9 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS02360 4f48b94c6b8951dada4c78fed7cf7aea 2212 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 1481 1535 9.3E-7 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS02360 4f48b94c6b8951dada4c78fed7cf7aea 2212 SUPERFAMILY SSF51735 1772 2012 1.11E-47 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS02360 4f48b94c6b8951dada4c78fed7cf7aea 2212 SMART SM00826 980 1148 2.5E-81 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS02360 4f48b94c6b8951dada4c78fed7cf7aea 2212 SMART SM00825 Beta-ketoacyl synthase 38 462 2.9E-219 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS02360 4f48b94c6b8951dada4c78fed7cf7aea 2212 SMART SM00823 Phosphopantetheine attachment site 2060 2132 2.2E-29 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS02360 4f48b94c6b8951dada4c78fed7cf7aea 2212 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 199 215 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS02360 4f48b94c6b8951dada4c78fed7cf7aea 2212 SUPERFAMILY SSF51735 1266 1439 2.44E-29 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS02360 4f48b94c6b8951dada4c78fed7cf7aea 2212 Gene3D G3DSA:3.40.47.10 28 298 2.9E-84 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS02360 4f48b94c6b8951dada4c78fed7cf7aea 2212 SUPERFAMILY SSF47336 2055 2138 7.07E-21 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS02360 4f48b94c6b8951dada4c78fed7cf7aea 2212 SUPERFAMILY SSF50129 1472 1597 1.46E-25 T 29-03-2018 IPR011032 GroES-like SMALA_RS09580 37a39f44f72237fbf98a73b7144cfc52 334 PIRSF PIRSF000149 1 332 2.2E-135 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMALA_RS09580 37a39f44f72237fbf98a73b7144cfc52 334 SMART SM00846 3 153 3.6E-94 T 29-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMALA_RS09580 37a39f44f72237fbf98a73b7144cfc52 334 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 103 1.4E-36 T 29-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMALA_RS09580 37a39f44f72237fbf98a73b7144cfc52 334 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 325 6.3E-139 T 29-03-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMALA_RS09580 37a39f44f72237fbf98a73b7144cfc52 334 Gene3D G3DSA:3.40.50.720 1 162 3.2E-77 T 29-03-2018 SMALA_RS09580 37a39f44f72237fbf98a73b7144cfc52 334 SUPERFAMILY SSF55347 153 314 5.66E-71 T 29-03-2018 SMALA_RS09580 37a39f44f72237fbf98a73b7144cfc52 334 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 158 313 2.5E-69 T 29-03-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMALA_RS09580 37a39f44f72237fbf98a73b7144cfc52 334 SUPERFAMILY SSF51735 2 179 2.8E-63 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS09580 37a39f44f72237fbf98a73b7144cfc52 334 Gene3D G3DSA:3.30.360.10 163 315 1.2E-68 T 29-03-2018 SMALA_RS09580 37a39f44f72237fbf98a73b7144cfc52 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 270 285 9.6E-41 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMALA_RS09580 37a39f44f72237fbf98a73b7144cfc52 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 110 123 9.6E-41 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMALA_RS09580 37a39f44f72237fbf98a73b7144cfc52 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 147 165 9.6E-41 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMALA_RS09580 37a39f44f72237fbf98a73b7144cfc52 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 174 190 9.6E-41 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMALA_RS09580 37a39f44f72237fbf98a73b7144cfc52 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 230 247 9.6E-41 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMALA_RS21820 15f9ed15f094b233fafcdce3ca297704 267 Gene3D G3DSA:1.10.10.10 14 80 1.8E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS21820 15f9ed15f094b233fafcdce3ca297704 267 SUPERFAMILY SSF46785 17 89 2.29E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS21820 15f9ed15f094b233fafcdce3ca297704 267 Hamap MF_01131 Redox-sensing transcriptional repressor Rex [rex]. 11 219 36.751 T 29-03-2018 IPR022876 Redox-sensing transcriptional repressor Rex GO:0005737|GO:0045892|GO:0051775 SMALA_RS21820 15f9ed15f094b233fafcdce3ca297704 267 Gene3D G3DSA:3.40.50.720 81 196 7.3E-20 T 29-03-2018 SMALA_RS21820 15f9ed15f094b233fafcdce3ca297704 267 SUPERFAMILY SSF51735 93 214 5.64E-28 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS21820 15f9ed15f094b233fafcdce3ca297704 267 SMART SM00881 89 190 6.4E-17 T 29-03-2018 IPR003781 CoA-binding GO:0048037 SMALA_RS21820 15f9ed15f094b233fafcdce3ca297704 267 Pfam PF06971 Putative DNA-binding protein N-terminus 16 63 4.6E-19 T 29-03-2018 IPR009718 Rex DNA-binding, C-terminal domain GO:0005737|GO:0045892|GO:0051775 SMALA_RS21820 15f9ed15f094b233fafcdce3ca297704 267 Pfam PF02629 CoA binding domain 91 188 3.2E-22 T 29-03-2018 IPR003781 CoA-binding GO:0048037 SMALA_RS14080 d71d68c3847a2306071d44b3aa1a7b25 265 Gene3D G3DSA:3.20.20.150 1 264 1.1E-56 T 29-03-2018 SMALA_RS14080 d71d68c3847a2306071d44b3aa1a7b25 265 Pfam PF01261 Xylose isomerase-like TIM barrel 20 212 1.5E-31 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SMALA_RS14080 d71d68c3847a2306071d44b3aa1a7b25 265 SUPERFAMILY SSF51658 5 261 2.49E-47 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SMALA_RS40010 fd0738acfdf2c8687efcf0cc17997c98 248 SUPERFAMILY SSF51735 5 246 1.33E-76 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS40010 fd0738acfdf2c8687efcf0cc17997c98 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 4.9E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40010 fd0738acfdf2c8687efcf0cc17997c98 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 4.9E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40010 fd0738acfdf2c8687efcf0cc17997c98 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 4.9E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40010 fd0738acfdf2c8687efcf0cc17997c98 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 168 4.9E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40010 fd0738acfdf2c8687efcf0cc17997c98 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 4.9E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40010 fd0738acfdf2c8687efcf0cc17997c98 248 Gene3D G3DSA:3.40.50.720 48 247 1.0E-57 T 29-03-2018 SMALA_RS40010 fd0738acfdf2c8687efcf0cc17997c98 248 Gene3D G3DSA:3.40.50.720 2 47 7.8E-12 T 29-03-2018 SMALA_RS40010 fd0738acfdf2c8687efcf0cc17997c98 248 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 184 2.4E-4 T 29-03-2018 SMALA_RS40010 fd0738acfdf2c8687efcf0cc17997c98 248 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 246 4.9E-59 T 29-03-2018 SMALA_RS40010 fd0738acfdf2c8687efcf0cc17997c98 248 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 136 164 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMALA_RS20275 73c9f31e4d59d468681e2c024e989a92 203 Gene3D G3DSA:1.10.357.10 68 202 3.8E-19 T 29-03-2018 SMALA_RS20275 73c9f31e4d59d468681e2c024e989a92 203 Pfam PF16859 Bacterial transcriptional repressor C-terminal 80 189 9.5E-24 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS20275 73c9f31e4d59d468681e2c024e989a92 203 Gene3D G3DSA:1.10.10.60 1 67 1.3E-11 T 29-03-2018 SMALA_RS20275 73c9f31e4d59d468681e2c024e989a92 203 SUPERFAMILY SSF48498 80 197 8.22E-23 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS20275 73c9f31e4d59d468681e2c024e989a92 203 SUPERFAMILY SSF46689 14 73 2.72E-9 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS02085 8dc7005bd2489261d6a511e69a3311e1 348 SMART SM00028 167 200 70.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS02085 8dc7005bd2489261d6a511e69a3311e1 348 SMART SM00028 248 281 0.25 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS02085 8dc7005bd2489261d6a511e69a3311e1 348 SUPERFAMILY SSF48452 135 303 1.65E-19 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS02085 8dc7005bd2489261d6a511e69a3311e1 348 Pfam PF13181 Tetratricopeptide repeat 254 276 0.04 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS02085 8dc7005bd2489261d6a511e69a3311e1 348 Gene3D G3DSA:1.25.40.10 18 160 1.7E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS02085 8dc7005bd2489261d6a511e69a3311e1 348 Gene3D G3DSA:1.25.40.10 161 260 1.1E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS02085 8dc7005bd2489261d6a511e69a3311e1 348 Pfam PF13424 Tetratricopeptide repeat 133 197 4.0E-7 T 29-03-2018 SMALA_RS02085 8dc7005bd2489261d6a511e69a3311e1 348 Gene3D G3DSA:1.25.40.10 261 336 3.1E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS36610 30f8bffbc1ac898add75828b7ff17866 378 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 95 119 - T 29-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 SMALA_RS36610 30f8bffbc1ac898add75828b7ff17866 378 SUPERFAMILY SSF53613 61 354 1.18E-58 T 29-03-2018 IPR029056 Ribokinase-like SMALA_RS36610 30f8bffbc1ac898add75828b7ff17866 378 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 314 327 - T 29-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 SMALA_RS36610 30f8bffbc1ac898add75828b7ff17866 378 Gene3D G3DSA:1.10.10.10 1 58 1.4E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS36610 30f8bffbc1ac898add75828b7ff17866 378 Gene3D G3DSA:3.40.1190.20 59 373 3.2E-61 T 29-03-2018 IPR029056 Ribokinase-like SMALA_RS36610 30f8bffbc1ac898add75828b7ff17866 378 Pfam PF00294 pfkB family carbohydrate kinase 62 357 5.6E-53 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB SMALA_RS36610 30f8bffbc1ac898add75828b7ff17866 378 Pfam PF13412 Winged helix-turn-helix DNA-binding 4 49 2.8E-6 T 29-03-2018 SMALA_RS36610 30f8bffbc1ac898add75828b7ff17866 378 SUPERFAMILY SSF46785 1 56 2.4E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS15355 7ddac161538f81d3abca0ee96ced53bd 447 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 7 439 3.5E-130 T 29-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMALA_RS15355 7ddac161538f81d3abca0ee96ced53bd 447 SUPERFAMILY SSF55205 6 440 3.27E-111 T 29-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 SMALA_RS15355 7ddac161538f81d3abca0ee96ced53bd 447 Gene3D G3DSA:3.65.10.10 25 228 2.9E-40 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 SMALA_RS15355 7ddac161538f81d3abca0ee96ced53bd 447 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 5 441 35.263 T 29-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMALA_RS15355 7ddac161538f81d3abca0ee96ced53bd 447 Gene3D G3DSA:3.65.10.10 229 441 2.0E-42 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 SMALA_RS15355 7ddac161538f81d3abca0ee96ced53bd 447 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 11 431 3.4E-57 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 Pfam PF00550 Phosphopantetheine attachment site 4121 4181 1.2E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 Pfam PF00550 Phosphopantetheine attachment site 3084 3145 5.5E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 Pfam PF00550 Phosphopantetheine attachment site 978 1039 8.8E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 Pfam PF00550 Phosphopantetheine attachment site 6291 6351 1.7E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 Pfam PF00550 Phosphopantetheine attachment site 5188 5249 5.1E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 Pfam PF00550 Phosphopantetheine attachment site 2016 2077 2.6E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 ProSitePatterns PS00455 Putative AMP-binding domain signature. 612 623 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 Gene3D G3DSA:3.40.50.980 5920 6085 4.9E-39 T 29-03-2018 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 Gene3D G3DSA:3.40.50.980 618 772 1.5E-34 T 29-03-2018 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 Gene3D G3DSA:3.40.50.980 1665 1812 8.3E-22 T 29-03-2018 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 Gene3D G3DSA:3.40.50.980 4827 4982 1.8E-32 T 29-03-2018 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 Gene3D G3DSA:3.40.50.980 3770 3916 3.0E-22 T 29-03-2018 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 SUPERFAMILY SSF52777 6 205 1.22E-40 T 29-03-2018 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 Gene3D G3DSA:3.40.50.980 4671 4826 2.8E-47 T 29-03-2018 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 Gene3D G3DSA:3.40.50.980 460 617 1.9E-45 T 29-03-2018 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 SUPERFAMILY SSF56801 3597 4131 1.27E-144 T 29-03-2018 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 Gene3D G3DSA:3.40.50.980 2564 2709 1.7E-36 T 29-03-2018 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 SUPERFAMILY SSF52777 6557 6838 1.22E-34 T 29-03-2018 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 Gene3D G3DSA:3.30.300.30 5070 5190 1.2E-41 T 29-03-2018 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 Gene3D G3DSA:3.30.300.30 860 980 1.3E-40 T 29-03-2018 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 Gene3D G3DSA:3.30.300.30 2966 3084 2.9E-41 T 29-03-2018 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 Gene3D G3DSA:3.30.300.30 4006 4123 1.2E-42 T 29-03-2018 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 Gene3D G3DSA:3.30.300.30 1901 2018 8.1E-43 T 29-03-2018 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 Gene3D G3DSA:3.30.300.30 6172 6294 1.6E-41 T 29-03-2018 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 Gene3D G3DSA:3.40.50.980 5782 5919 6.7E-41 T 29-03-2018 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 Gene3D G3DSA:3.40.50.980 3630 3769 4.8E-42 T 29-03-2018 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 Gene3D G3DSA:3.40.50.980 1525 1664 1.9E-43 T 29-03-2018 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1658 1669 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 Gene3D G3DSA:1.10.1200.10 2019 2079 4.0E-21 T 29-03-2018 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 Gene3D G3DSA:1.10.1200.10 4124 4180 2.5E-21 T 29-03-2018 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 Gene3D G3DSA:1.10.1200.10 981 1038 2.1E-23 T 29-03-2018 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 Gene3D G3DSA:1.10.1200.10 5191 5251 1.6E-23 T 29-03-2018 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 SUPERFAMILY SSF56801 5746 6302 3.27E-160 T 29-03-2018 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 SUPERFAMILY SSF56801 426 988 7.59E-159 T 29-03-2018 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 Pfam PF00668 Condensation domain 6369 6842 6.4E-45 T 29-03-2018 IPR001242 Condensation domain SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 Pfam PF00668 Condensation domain 5269 5386 5.2E-22 T 29-03-2018 IPR001242 Condensation domain SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 Pfam PF00668 Condensation domain 9 445 1.6E-86 T 29-03-2018 IPR001242 Condensation domain SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 Pfam PF00668 Condensation domain 3166 3617 1.7E-91 T 29-03-2018 IPR001242 Condensation domain SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 Pfam PF00668 Condensation domain 1060 1512 4.4E-90 T 29-03-2018 IPR001242 Condensation domain SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 Pfam PF00668 Condensation domain 4201 4657 1.2E-83 T 29-03-2018 IPR001242 Condensation domain SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 Pfam PF00668 Condensation domain 2096 2551 2.3E-92 T 29-03-2018 IPR001242 Condensation domain SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 Pfam PF00668 Condensation domain 5437 5768 8.8E-67 T 29-03-2018 IPR001242 Condensation domain SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 ProSitePatterns PS00455 Putative AMP-binding domain signature. 5914 5925 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 Gene3D G3DSA:1.10.1200.10 6295 6355 2.7E-23 T 29-03-2018 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 SUPERFAMILY SSF52777 4392 4663 1.03E-57 T 29-03-2018 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 Gene3D G3DSA:3.30.559.10 2080 2297 3.2E-43 T 29-03-2018 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 Gene3D G3DSA:3.30.559.10 3144 3367 9.8E-44 T 29-03-2018 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 Gene3D G3DSA:3.30.559.10 4181 4406 3.3E-41 T 29-03-2018 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 Gene3D G3DSA:3.30.559.10 6 211 4.2E-38 T 29-03-2018 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 Gene3D G3DSA:3.30.559.10 1039 1261 1.0E-43 T 29-03-2018 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 SUPERFAMILY SSF52777 6369 6569 7.78E-31 T 29-03-2018 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 SUPERFAMILY SSF52777 5435 5519 5.23E-12 T 29-03-2018 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 SUPERFAMILY SSF47336 2006 2078 1.11E-18 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 SUPERFAMILY SSF52777 2099 2272 6.78E-47 T 29-03-2018 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 ProSitePatterns PS00455 Putative AMP-binding domain signature. 3763 3774 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 Gene3D G3DSA:2.30.38.10 4984 5068 2.8E-21 T 29-03-2018 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 Gene3D G3DSA:2.30.38.10 1816 1899 2.7E-24 T 29-03-2018 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 Gene3D G3DSA:2.30.38.10 774 858 6.1E-22 T 29-03-2018 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 Gene3D G3DSA:2.30.38.10 6089 6170 1.5E-22 T 29-03-2018 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 SUPERFAMILY SSF52777 2283 2536 1.78E-55 T 29-03-2018 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 SUPERFAMILY SSF47336 968 1040 2.49E-19 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 Pfam PF00501 AMP-binding enzyme 2572 2971 2.9E-101 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 Pfam PF00501 AMP-binding enzyme 1533 1906 6.0E-83 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 Pfam PF00501 AMP-binding enzyme 4678 5075 3.4E-98 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 Pfam PF00501 AMP-binding enzyme 5790 6177 2.7E-96 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 Pfam PF00501 AMP-binding enzyme 3640 4011 8.6E-85 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 Pfam PF00501 AMP-binding enzyme 467 865 3.4E-98 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 SUPERFAMILY SSF52777 191 454 9.56E-56 T 29-03-2018 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 SUPERFAMILY SSF52777 3351 3623 9.12E-58 T 29-03-2018 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3105 3120 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 ProSitePatterns PS00012 Phosphopantetheine attachment site. 5209 5224 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 Gene3D G3DSA:3.30.559.10 5252 5493 1.1E-38 T 29-03-2018 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 ProSitePatterns PS00012 Phosphopantetheine attachment site. 6313 6328 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2037 2052 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 Gene3D G3DSA:1.10.1200.10 3085 3143 2.3E-23 T 29-03-2018 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 SUPERFAMILY SSF56801 4636 5198 4.58E-157 T 29-03-2018 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 5811 6201 5.3E-128 T 29-03-2018 IPR010071 Amino acid adenylation domain SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 4699 5099 9.0E-133 T 29-03-2018 IPR010071 Amino acid adenylation domain SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1554 1930 2.3E-118 T 29-03-2018 IPR010071 Amino acid adenylation domain SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 3659 4035 7.1E-120 T 29-03-2018 IPR010071 Amino acid adenylation domain SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2593 2995 1.4E-132 T 29-03-2018 IPR010071 Amino acid adenylation domain SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 488 889 1.0E-130 T 29-03-2018 IPR010071 Amino acid adenylation domain SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 SMART SM01294 6290 6352 0.0079 T 29-03-2018 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 SUPERFAMILY SSF52777 5505 5758 1.33E-62 T 29-03-2018 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 SUPERFAMILY SSF47336 4111 4183 7.72E-19 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 6698 6861 6.3E-38 T 29-03-2018 IPR010060 Non-ribosomal peptide synthase SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 SUPERFAMILY SSF47336 6283 6351 3.93E-19 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 Pfam PF13193 AMP-binding enzyme C-terminal domain 873 949 3.5E-14 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 Pfam PF13193 AMP-binding enzyme C-terminal domain 2979 3055 2.4E-14 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 Pfam PF13193 AMP-binding enzyme C-terminal domain 4019 4092 1.4E-14 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 Pfam PF13193 AMP-binding enzyme C-terminal domain 6185 6262 2.2E-14 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 Pfam PF13193 AMP-binding enzyme C-terminal domain 1914 1987 1.3E-14 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 Pfam PF13193 AMP-binding enzyme C-terminal domain 5083 5159 9.7E-15 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 SUPERFAMILY SSF52777 5271 5388 2.56E-27 T 29-03-2018 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 SUPERFAMILY SSF56801 1493 2026 3.66E-145 T 29-03-2018 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 SUPERFAMILY SSF47336 3074 3146 1.57E-19 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 ProSitePatterns PS00455 Putative AMP-binding domain signature. 4822 4833 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 SUPERFAMILY SSF52777 4204 4381 2.78E-44 T 29-03-2018 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 SUPERFAMILY SSF52777 1062 1233 2.89E-46 T 29-03-2018 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2718 2729 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 SUPERFAMILY SSF52777 3168 3339 1.89E-48 T 29-03-2018 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 SMART SM00823 Phosphopantetheine attachment site 975 1044 3.9E-7 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 SMART SM00823 Phosphopantetheine attachment site 5185 5254 7.4E-7 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 SMART SM00823 Phosphopantetheine attachment site 6289 6357 1.2E-10 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 SMART SM00823 Phosphopantetheine attachment site 2013 2082 4.7E-4 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 SMART SM00823 Phosphopantetheine attachment site 3081 3150 9.4E-7 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 SMART SM00823 Phosphopantetheine attachment site 4118 4187 8.3E-4 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4142 4157 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 Gene3D G3DSA:2.30.38.10 3920 4001 1.3E-25 T 29-03-2018 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 Gene3D G3DSA:2.30.38.10 2884 2961 1.6E-23 T 29-03-2018 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 Gene3D G3DSA:3.40.50.980 2710 2883 1.2E-47 T 29-03-2018 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 Gene3D G3DSA:3.30.559.10 6356 6566 4.2E-29 T 29-03-2018 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 ProSitePatterns PS00012 Phosphopantetheine attachment site. 999 1014 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 SUPERFAMILY SSF47336 5178 5251 1.96E-19 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 SUPERFAMILY SSF52777 1245 1518 4.45E-59 T 29-03-2018 SMALA_RS38245 274bb78501a7d0209e8e09e25df63c01 6869 SUPERFAMILY SSF56801 2532 3094 6.41E-158 T 29-03-2018 SMALA_RS27360 ba7a75d0098740244b1222cadcc0458f 517 Gene3D G3DSA:3.40.190.10 233 329 6.6E-4 T 29-03-2018 SMALA_RS27360 ba7a75d0098740244b1222cadcc0458f 517 SUPERFAMILY SSF53850 235 511 5.43E-56 T 29-03-2018 SMALA_RS27360 ba7a75d0098740244b1222cadcc0458f 517 Gene3D G3DSA:3.40.190.10 451 514 0.22 T 29-03-2018 SMALA_RS27360 ba7a75d0098740244b1222cadcc0458f 517 Gene3D G3DSA:3.40.190.10 330 450 1.5E-29 T 29-03-2018 SMALA_RS27360 ba7a75d0098740244b1222cadcc0458f 517 Pfam PF12849 PBP superfamily domain 230 487 5.5E-31 T 29-03-2018 IPR024370 PBP domain SMALA_RS39815 3b048d62a337def0640924549b1bcc05 321 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 59 283 1.7E-49 T 29-03-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 SMALA_RS39815 3b048d62a337def0640924549b1bcc05 321 Pfam PF01791 DeoC/LacD family aldolase 53 270 5.5E-22 T 29-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 SMALA_RS39815 3b048d62a337def0640924549b1bcc05 321 SUPERFAMILY SSF51569 58 301 4.19E-73 T 29-03-2018 SMALA_RS39815 3b048d62a337def0640924549b1bcc05 321 Gene3D G3DSA:3.20.20.70 34 319 6.0E-93 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS39815 3b048d62a337def0640924549b1bcc05 321 SMART SM01133 57 302 6.2E-73 T 29-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 SMALA_RS39815 3b048d62a337def0640924549b1bcc05 321 PIRSF PIRSF001357 51 311 2.2E-80 T 29-03-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 SMALA_RS09550 f7c78cc89c38aca6b08313d73236150c 550 SUPERFAMILY SSF53697 9 548 1.17E-207 T 29-03-2018 SMALA_RS09550 f7c78cc89c38aca6b08313d73236150c 550 Gene3D G3DSA:3.40.50.10490 263 511 2.7E-116 T 29-03-2018 SMALA_RS09550 f7c78cc89c38aca6b08313d73236150c 550 Pfam PF00342 Phosphoglucose isomerase 54 541 2.6E-217 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMALA_RS09550 f7c78cc89c38aca6b08313d73236150c 550 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 497 514 - T 29-03-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMALA_RS09550 f7c78cc89c38aca6b08313d73236150c 550 Gene3D G3DSA:1.10.1390.10 512 550 8.4E-19 T 29-03-2018 IPR023096 Phosphoglucose isomerase, C-terminal GO:0004347|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMALA_RS09550 f7c78cc89c38aca6b08313d73236150c 550 Gene3D G3DSA:3.40.50.10490 146 262 3.1E-54 T 29-03-2018 SMALA_RS09550 f7c78cc89c38aca6b08313d73236150c 550 Gene3D G3DSA:3.40.50.10490 1 145 6.9E-44 T 29-03-2018 SMALA_RS09550 f7c78cc89c38aca6b08313d73236150c 550 PRINTS PR00662 Glucose-6-phosphate isomerase signature 152 171 7.6E-54 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMALA_RS09550 f7c78cc89c38aca6b08313d73236150c 550 PRINTS PR00662 Glucose-6-phosphate isomerase signature 483 497 7.6E-54 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMALA_RS09550 f7c78cc89c38aca6b08313d73236150c 550 PRINTS PR00662 Glucose-6-phosphate isomerase signature 265 283 7.6E-54 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMALA_RS09550 f7c78cc89c38aca6b08313d73236150c 550 PRINTS PR00662 Glucose-6-phosphate isomerase signature 497 510 7.6E-54 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMALA_RS09550 f7c78cc89c38aca6b08313d73236150c 550 PRINTS PR00662 Glucose-6-phosphate isomerase signature 465 483 7.6E-54 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMALA_RS09550 f7c78cc89c38aca6b08313d73236150c 550 PRINTS PR00662 Glucose-6-phosphate isomerase signature 342 363 7.6E-54 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMALA_RS09550 f7c78cc89c38aca6b08313d73236150c 550 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 48 524 41.267 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMALA_RS11790 c940236de2d63ab88fec8f6a9ea06992 570 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 19 33 - T 29-03-2018 IPR019775 WD40 repeat, conserved site SMALA_RS11790 c940236de2d63ab88fec8f6a9ea06992 570 SUPERFAMILY SSF50998 9 238 1.8E-46 T 29-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily SMALA_RS11790 c940236de2d63ab88fec8f6a9ea06992 570 SUPERFAMILY SSF50998 401 525 1.8E-46 T 29-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily SMALA_RS11790 c940236de2d63ab88fec8f6a9ea06992 570 PRINTS PR00320 G protein beta WD-40 repeat signature 223 237 2.7E-5 T 29-03-2018 IPR020472 G-protein beta WD-40 repeat SMALA_RS11790 c940236de2d63ab88fec8f6a9ea06992 570 PRINTS PR00320 G protein beta WD-40 repeat signature 60 74 2.7E-5 T 29-03-2018 IPR020472 G-protein beta WD-40 repeat SMALA_RS11790 c940236de2d63ab88fec8f6a9ea06992 570 PRINTS PR00320 G protein beta WD-40 repeat signature 143 157 2.7E-5 T 29-03-2018 IPR020472 G-protein beta WD-40 repeat SMALA_RS11790 c940236de2d63ab88fec8f6a9ea06992 570 Gene3D G3DSA:2.130.10.10 107 167 4.1E-14 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMALA_RS11790 c940236de2d63ab88fec8f6a9ea06992 570 Pfam PF00400 WD domain, G-beta repeat 119 155 1.4E-4 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 SMALA_RS11790 c940236de2d63ab88fec8f6a9ea06992 570 Pfam PF00400 WD domain, G-beta repeat 44 73 0.0032 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 SMALA_RS11790 c940236de2d63ab88fec8f6a9ea06992 570 Pfam PF00400 WD domain, G-beta repeat 483 512 0.031 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 SMALA_RS11790 c940236de2d63ab88fec8f6a9ea06992 570 SMART SM00320 1 32 14.0 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 SMALA_RS11790 c940236de2d63ab88fec8f6a9ea06992 570 SMART SM00320 481 520 3.9E-4 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 SMALA_RS11790 c940236de2d63ab88fec8f6a9ea06992 570 SMART SM00320 117 156 3.3E-8 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 SMALA_RS11790 c940236de2d63ab88fec8f6a9ea06992 570 SMART SM00320 198 236 1.1 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 SMALA_RS11790 c940236de2d63ab88fec8f6a9ea06992 570 SMART SM00320 441 480 3.8 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 SMALA_RS11790 c940236de2d63ab88fec8f6a9ea06992 570 SMART SM00320 523 562 90.0 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 SMALA_RS11790 c940236de2d63ab88fec8f6a9ea06992 570 SMART SM00320 35 73 7.0E-5 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 SMALA_RS11790 c940236de2d63ab88fec8f6a9ea06992 570 SMART SM00320 76 115 4.8E-4 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 SMALA_RS11790 c940236de2d63ab88fec8f6a9ea06992 570 SMART SM00320 401 438 0.28 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 SMALA_RS11790 c940236de2d63ab88fec8f6a9ea06992 570 Gene3D G3DSA:2.130.10.10 1 70 7.7E-16 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMALA_RS11790 c940236de2d63ab88fec8f6a9ea06992 570 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 223 237 - T 29-03-2018 IPR019775 WD40 repeat, conserved site SMALA_RS11790 c940236de2d63ab88fec8f6a9ea06992 570 SUPERFAMILY SSF63829 176 386 5.36E-8 T 29-03-2018 SMALA_RS11790 c940236de2d63ab88fec8f6a9ea06992 570 Gene3D G3DSA:2.130.10.10 435 565 4.8E-22 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMALA_RS11790 c940236de2d63ab88fec8f6a9ea06992 570 Gene3D G3DSA:1.10.10.670 71 106 2.7E-11 T 29-03-2018 SMALA_RS11790 c940236de2d63ab88fec8f6a9ea06992 570 Gene3D G3DSA:2.130.10.10 169 288 8.8E-10 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMALA_RS11790 c940236de2d63ab88fec8f6a9ea06992 570 Gene3D G3DSA:2.130.10.10 289 434 4.2E-9 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMALA_RS34265 db0b1dbf728f849b02c85f1cd1ffcec0 772 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 110 186 9.2E-15 T 29-03-2018 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 SMALA_RS34265 db0b1dbf728f849b02c85f1cd1ffcec0 772 SUPERFAMILY SSF51445 320 603 3.49E-58 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS34265 db0b1dbf728f849b02c85f1cd1ffcec0 772 Gene3D G3DSA:3.20.20.80 333 603 4.4E-34 T 29-03-2018 SMALA_RS34265 db0b1dbf728f849b02c85f1cd1ffcec0 772 Gene3D G3DSA:2.60.120.260 52 227 1.2E-41 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS34265 db0b1dbf728f849b02c85f1cd1ffcec0 772 Gene3D G3DSA:2.60.40.10 228 323 7.7E-13 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS34265 db0b1dbf728f849b02c85f1cd1ffcec0 772 SUPERFAMILY SSF49303 230 323 3.17E-9 T 29-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 SMALA_RS34265 db0b1dbf728f849b02c85f1cd1ffcec0 772 Pfam PF05270 Alpha-L-arabinofuranosidase B (ABFB) domain 628 766 1.0E-49 T 29-03-2018 IPR007934 Alpha-L-arabinofuranosidase B, arabinose-binding domain GO:0046373|GO:0046556 SMALA_RS34265 db0b1dbf728f849b02c85f1cd1ffcec0 772 SUPERFAMILY SSF49785 52 226 6.56E-43 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS34265 db0b1dbf728f849b02c85f1cd1ffcec0 772 Pfam PF00703 Glycosyl hydrolases family 2 240 322 1.8E-6 T 29-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 SMALA_RS34265 db0b1dbf728f849b02c85f1cd1ffcec0 772 Gene3D G3DSA:2.80.10.50 614 772 4.4E-50 T 29-03-2018 SMALA_RS34265 db0b1dbf728f849b02c85f1cd1ffcec0 772 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 364 477 1.1E-4 T 29-03-2018 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 SMALA_RS34265 db0b1dbf728f849b02c85f1cd1ffcec0 772 SUPERFAMILY SSF110221 617 771 9.55E-53 T 29-03-2018 IPR007934 Alpha-L-arabinofuranosidase B, arabinose-binding domain GO:0046373|GO:0046556 SMALA_RS12420 315e8b2e789108f3dbe2954b99fd5939 225 SUPERFAMILY SSF52172 2 180 1.16E-39 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS12420 315e8b2e789108f3dbe2954b99fd5939 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 220 6.4E-24 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS12420 315e8b2e789108f3dbe2954b99fd5939 225 Gene3D G3DSA:3.40.50.2300 1 119 4.2E-34 T 29-03-2018 SMALA_RS12420 315e8b2e789108f3dbe2954b99fd5939 225 Pfam PF00072 Response regulator receiver domain 3 112 1.6E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS12420 315e8b2e789108f3dbe2954b99fd5939 225 Gene3D G3DSA:1.10.10.10 120 224 2.2E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS12420 315e8b2e789108f3dbe2954b99fd5939 225 SMART SM00448 1 112 1.8E-42 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS12420 315e8b2e789108f3dbe2954b99fd5939 225 SMART SM00862 145 220 1.7E-23 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS32560 6061200470374237b36e4baa2448df88 351 SUPERFAMILY SSF55021 253 331 5.61E-17 T 29-03-2018 SMALA_RS32560 6061200470374237b36e4baa2448df88 351 SUPERFAMILY SSF52540 2 245 4.6E-80 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS32560 6061200470374237b36e4baa2448df88 351 Pfam PF00005 ABC transporter 21 175 1.6E-34 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS32560 6061200470374237b36e4baa2448df88 351 SMART SM00930 257 332 1.4E-19 T 29-03-2018 IPR018449 NIL domain SMALA_RS32560 6061200470374237b36e4baa2448df88 351 Gene3D G3DSA:3.30.70.260 244 334 5.5E-20 T 29-03-2018 SMALA_RS32560 6061200470374237b36e4baa2448df88 351 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS32560 6061200470374237b36e4baa2448df88 351 Gene3D G3DSA:3.40.50.300 1 243 1.8E-76 T 29-03-2018 SMALA_RS32560 6061200470374237b36e4baa2448df88 351 SMART SM00382 30 232 7.8E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS32560 6061200470374237b36e4baa2448df88 351 Pfam PF09383 NIL domain 259 331 1.2E-17 T 29-03-2018 IPR018449 NIL domain SMALA_RS29235 bc89d3560fdb232588945e7e8af59e1f 227 Pfam PF00072 Response regulator receiver domain 4 112 4.0E-29 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS29235 bc89d3560fdb232588945e7e8af59e1f 227 Gene3D G3DSA:3.40.50.2300 2 119 1.3E-37 T 29-03-2018 SMALA_RS29235 bc89d3560fdb232588945e7e8af59e1f 227 SMART SM00862 149 225 6.0E-25 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS29235 bc89d3560fdb232588945e7e8af59e1f 227 SUPERFAMILY SSF52172 2 183 1.42E-40 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS29235 bc89d3560fdb232588945e7e8af59e1f 227 Gene3D G3DSA:1.10.10.10 120 227 1.0E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS29235 bc89d3560fdb232588945e7e8af59e1f 227 SMART SM00448 2 112 5.4E-41 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS29235 bc89d3560fdb232588945e7e8af59e1f 227 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 225 5.1E-24 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS30760 3aecc50c5dcc06c2be7e4a98ad60a6f4 439 Gene3D G3DSA:3.90.1150.10 315 433 1.9E-34 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS30760 3aecc50c5dcc06c2be7e4a98ad60a6f4 439 Gene3D G3DSA:3.40.640.10 180 314 6.3E-36 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS30760 3aecc50c5dcc06c2be7e4a98ad60a6f4 439 Gene3D G3DSA:3.90.1150.10 6 166 9.8E-38 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS30760 3aecc50c5dcc06c2be7e4a98ad60a6f4 439 SUPERFAMILY SSF53383 9 429 1.9E-104 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS30760 3aecc50c5dcc06c2be7e4a98ad60a6f4 439 Pfam PF00202 Aminotransferase class-III 27 429 1.3E-85 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMALA_RS30760 3aecc50c5dcc06c2be7e4a98ad60a6f4 439 PIRSF PIRSF000521 124 432 6.4E-35 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMALA_RS30760 3aecc50c5dcc06c2be7e4a98ad60a6f4 439 PIRSF PIRSF000521 22 132 6.4E-4 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMALA_RS00365 98ed6833169968ca210448998b191f30 507 Pfam PF07690 Major Facilitator Superfamily 18 408 4.5E-53 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS00365 98ed6833169968ca210448998b191f30 507 Gene3D G3DSA:1.20.1250.20 255 504 5.2E-28 T 29-03-2018 SMALA_RS00365 98ed6833169968ca210448998b191f30 507 Gene3D G3DSA:1.20.1250.20 7 196 6.0E-37 T 29-03-2018 SMALA_RS00365 98ed6833169968ca210448998b191f30 507 PRINTS PR01036 Tetracycline resistance protein TetB signature 16 40 6.8E-9 T 29-03-2018 SMALA_RS00365 98ed6833169968ca210448998b191f30 507 PRINTS PR01036 Tetracycline resistance protein TetB signature 137 161 6.8E-9 T 29-03-2018 SMALA_RS00365 98ed6833169968ca210448998b191f30 507 PRINTS PR01036 Tetracycline resistance protein TetB signature 336 356 6.8E-9 T 29-03-2018 SMALA_RS00365 98ed6833169968ca210448998b191f30 507 PRINTS PR01036 Tetracycline resistance protein TetB signature 399 418 6.8E-9 T 29-03-2018 SMALA_RS00365 98ed6833169968ca210448998b191f30 507 PRINTS PR01036 Tetracycline resistance protein TetB signature 107 127 6.8E-9 T 29-03-2018 SMALA_RS00365 98ed6833169968ca210448998b191f30 507 ProSitePatterns PS00216 Sugar transport proteins signature 1. 67 83 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMALA_RS00365 98ed6833169968ca210448998b191f30 507 SUPERFAMILY SSF103473 6 199 8.11E-72 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS00365 98ed6833169968ca210448998b191f30 507 SUPERFAMILY SSF103473 247 418 8.11E-72 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS00365 98ed6833169968ca210448998b191f30 507 SUPERFAMILY SSF103473 461 491 8.11E-72 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS24610 327a543828a891d208826718b23d1205 581 SUPERFAMILY SSF52540 151 386 1.19E-32 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS24610 327a543828a891d208826718b23d1205 581 Pfam PF07811 TadE-like protein 464 506 5.7E-7 T 29-03-2018 IPR012495 TadE-like SMALA_RS24610 327a543828a891d208826718b23d1205 581 Gene3D G3DSA:3.40.50.300 148 387 1.8E-31 T 29-03-2018 SMALA_RS24610 327a543828a891d208826718b23d1205 581 SUPERFAMILY SSF52172 3 130 2.05E-8 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS24610 327a543828a891d208826718b23d1205 581 Gene3D G3DSA:3.40.50.2300 2 138 6.9E-9 T 29-03-2018 SMALA_RS24610 327a543828a891d208826718b23d1205 581 Pfam PF13614 AAA domain 151 312 1.4E-11 T 29-03-2018 IPR025669 AAA domain SMALA_RS22160 9930b1d08806795b997263b3229777aa 631 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 264 286 1.1E-9 T 29-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 SMALA_RS22160 9930b1d08806795b997263b3229777aa 631 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 60 84 1.1E-9 T 29-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 SMALA_RS22160 9930b1d08806795b997263b3229777aa 631 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 420 442 1.1E-9 T 29-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 SMALA_RS22160 9930b1d08806795b997263b3229777aa 631 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 86 106 1.1E-9 T 29-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 SMALA_RS22160 9930b1d08806795b997263b3229777aa 631 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 3 625 2.0E-237 T 29-03-2018 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS22160 9930b1d08806795b997263b3229777aa 631 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 66 123 6.3E-25 T 29-03-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS22160 9930b1d08806795b997263b3229777aa 631 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 159 180 4.5E-60 T 29-03-2018 SMALA_RS22160 9930b1d08806795b997263b3229777aa 631 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 112 132 4.5E-60 T 29-03-2018 SMALA_RS22160 9930b1d08806795b997263b3229777aa 631 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 246 272 4.5E-60 T 29-03-2018 SMALA_RS22160 9930b1d08806795b997263b3229777aa 631 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 421 440 4.5E-60 T 29-03-2018 SMALA_RS22160 9930b1d08806795b997263b3229777aa 631 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 224 245 4.5E-60 T 29-03-2018 SMALA_RS22160 9930b1d08806795b997263b3229777aa 631 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 314 326 4.5E-60 T 29-03-2018 SMALA_RS22160 9930b1d08806795b997263b3229777aa 631 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 84 109 4.5E-60 T 29-03-2018 SMALA_RS22160 9930b1d08806795b997263b3229777aa 631 Pfam PF00361 Proton-conducting membrane transporter 135 422 4.7E-84 T 29-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS41515 150db9e0dee6e7c6ffd2336787a9531c 502 Gene3D G3DSA:1.10.10.60 405 468 5.0E-8 T 29-03-2018 SMALA_RS41515 150db9e0dee6e7c6ffd2336787a9531c 502 Pfam PF07905 Purine catabolism regulatory protein-like family 8 124 1.0E-27 T 29-03-2018 IPR012914 Purine catabolism PurC-like domain SMALA_RS41515 150db9e0dee6e7c6ffd2336787a9531c 502 Pfam PF13556 PucR C-terminal helix-turn-helix domain 435 493 2.4E-16 T 29-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain SMALA_RS41515 150db9e0dee6e7c6ffd2336787a9531c 502 Gene3D G3DSA:3.40.1390.20 2 117 8.7E-4 T 29-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like SMALA_RS02305 fe155dfa57a2458cb38a0fd706d2c316 907 Pfam PF17203 Single cache domain 3 49 183 7.3E-18 T 29-03-2018 IPR033463 Single cache domain 3 SMALA_RS02305 fe155dfa57a2458cb38a0fd706d2c316 907 SMART SM00091 228 293 7.0E-4 T 29-03-2018 IPR000014 PAS domain SMALA_RS02305 fe155dfa57a2458cb38a0fd706d2c316 907 SMART SM00331 559 777 4.0E-18 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS02305 fe155dfa57a2458cb38a0fd706d2c316 907 Gene3D G3DSA:3.30.450.20 44 185 1.3E-20 T 29-03-2018 SMALA_RS02305 fe155dfa57a2458cb38a0fd706d2c316 907 Gene3D G3DSA:3.30.450.40 333 535 2.9E-31 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS02305 fe155dfa57a2458cb38a0fd706d2c316 907 SUPERFAMILY SSF55874 814 906 5.82E-6 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS02305 fe155dfa57a2458cb38a0fd706d2c316 907 Pfam PF01590 GAF domain 429 527 7.0E-6 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS02305 fe155dfa57a2458cb38a0fd706d2c316 907 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 583 777 1.6E-39 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS02305 fe155dfa57a2458cb38a0fd706d2c316 907 SUPERFAMILY SSF103190 54 184 5.1E-27 T 29-03-2018 IPR029151 Periplasmic sensor domain-like SMALA_RS02305 fe155dfa57a2458cb38a0fd706d2c316 907 SUPERFAMILY SSF55785 222 327 5.65E-6 T 29-03-2018 IPR000014 PAS domain SMALA_RS02305 fe155dfa57a2458cb38a0fd706d2c316 907 SUPERFAMILY SSF55781 451 538 1.59E-10 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS02305 fe155dfa57a2458cb38a0fd706d2c316 907 Gene3D G3DSA:3.30.450.20 218 332 1.0E-11 T 29-03-2018 SMALA_RS02305 fe155dfa57a2458cb38a0fd706d2c316 907 Gene3D G3DSA:3.30.565.10 781 906 2.8E-9 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS02305 fe155dfa57a2458cb38a0fd706d2c316 907 Gene3D G3DSA:3.60.40.10 536 780 5.7E-34 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS02305 fe155dfa57a2458cb38a0fd706d2c316 907 Pfam PF13581 Histidine kinase-like ATPase domain 791 898 3.1E-7 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS02305 fe155dfa57a2458cb38a0fd706d2c316 907 SUPERFAMILY SSF81606 620 776 1.18E-5 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS42775 c1295546985624b724c174086f97e782 257 Gene3D G3DSA:1.10.10.60 197 252 5.6E-6 T 29-03-2018 SMALA_RS12190 b64c1328104016470d381915333d2a29 520 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 116 184 2.5E-8 T 29-03-2018 SMALA_RS12190 b64c1328104016470d381915333d2a29 520 SUPERFAMILY SSF69318 433 511 2.2E-6 T 29-03-2018 SMALA_RS12190 b64c1328104016470d381915333d2a29 520 Gene3D G3DSA:2.130.10.130 124 246 1.3E-15 T 29-03-2018 SMALA_RS12190 b64c1328104016470d381915333d2a29 520 Gene3D G3DSA:2.130.10.130 23 123 7.3E-9 T 29-03-2018 SMALA_RS12190 b64c1328104016470d381915333d2a29 520 Gene3D G3DSA:2.60.40.680 287 393 7.1E-12 T 29-03-2018 SMALA_RS12190 b64c1328104016470d381915333d2a29 520 Gene3D G3DSA:2.60.40.680 394 443 7.1E-6 T 29-03-2018 SMALA_RS12190 b64c1328104016470d381915333d2a29 520 Gene3D G3DSA:2.60.40.680 453 515 4.3E-4 T 29-03-2018 SMALA_RS12190 b64c1328104016470d381915333d2a29 520 SUPERFAMILY SSF69318 54 248 1.05E-28 T 29-03-2018 SMALA_RS12190 b64c1328104016470d381915333d2a29 520 SUPERFAMILY SSF69318 275 418 1.05E-28 T 29-03-2018 SMALA_RS12190 b64c1328104016470d381915333d2a29 520 Pfam PF01839 FG-GAP repeat 378 406 7.6E-7 T 29-03-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 SMALA_RS12190 b64c1328104016470d381915333d2a29 520 SMART SM00191 105 161 31.0 T 29-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMALA_RS12190 b64c1328104016470d381915333d2a29 520 SMART SM00191 452 509 14.0 T 29-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMALA_RS12190 b64c1328104016470d381915333d2a29 520 SMART SM00191 162 215 35.0 T 29-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMALA_RS12190 b64c1328104016470d381915333d2a29 520 SMART SM00191 293 363 160.0 T 29-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMALA_RS12190 b64c1328104016470d381915333d2a29 520 SMART SM00191 374 430 1.0 T 29-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMALA_RS02960 09a0116504b460bf5c7c5cb03453c2c5 302 SUPERFAMILY SSF53448 8 210 1.41E-35 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS02960 09a0116504b460bf5c7c5cb03453c2c5 302 Pfam PF13641 Glycosyltransferase like family 2 6 208 4.6E-15 T 29-03-2018 SMALA_RS02960 09a0116504b460bf5c7c5cb03453c2c5 302 Gene3D G3DSA:3.90.550.10 2 251 1.1E-32 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS03135 c62c254d1ec05e63da4f2f230c7fe8d9 282 SUPERFAMILY SSF55447 182 281 1.1E-21 T 29-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal SMALA_RS03135 c62c254d1ec05e63da4f2f230c7fe8d9 282 Gene3D G3DSA:3.30.390.50 181 282 3.7E-21 T 29-03-2018 SMALA_RS03135 c62c254d1ec05e63da4f2f230c7fe8d9 282 SMART SM01092 182 279 2.0E-21 T 29-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal SMALA_RS03135 c62c254d1ec05e63da4f2f230c7fe8d9 282 Gene3D G3DSA:3.30.43.10 1 54 1.9E-19 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 SMALA_RS03135 c62c254d1ec05e63da4f2f230c7fe8d9 282 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 5 177 5.5E-43 T 29-03-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 SMALA_RS03135 c62c254d1ec05e63da4f2f230c7fe8d9 282 SUPERFAMILY SSF56176 1 177 5.61E-49 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SMALA_RS03135 c62c254d1ec05e63da4f2f230c7fe8d9 282 Gene3D G3DSA:3.30.465.10 64 177 4.4E-28 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SMALA_RS03135 c62c254d1ec05e63da4f2f230c7fe8d9 282 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 186 278 2.8E-14 T 29-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal SMALA_RS33670 6e30230b2bb3c6954d9d899e97f8ae96 507 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 262 269 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 SMALA_RS33670 6e30230b2bb3c6954d9d899e97f8ae96 507 Gene3D G3DSA:3.40.309.10 280 481 1.1E-63 T 29-03-2018 SMALA_RS33670 6e30230b2bb3c6954d9d899e97f8ae96 507 Pfam PF00171 Aldehyde dehydrogenase family 33 494 6.1E-159 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS33670 6e30230b2bb3c6954d9d899e97f8ae96 507 Gene3D G3DSA:3.40.605.10 9 279 1.5E-93 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS33670 6e30230b2bb3c6954d9d899e97f8ae96 507 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 295 306 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 SMALA_RS33670 6e30230b2bb3c6954d9d899e97f8ae96 507 SUPERFAMILY SSF53720 14 499 6.28E-160 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMALA_RS38480 774e4e6b280a249fa0807860686dc957 334 SMART SM00562 59 203 0.0077 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SMALA_RS38480 774e4e6b280a249fa0807860686dc957 334 Pfam PF00334 Nucleoside diphosphate kinase 57 199 4.5E-15 T 29-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SMALA_RS38480 774e4e6b280a249fa0807860686dc957 334 Gene3D G3DSA:3.30.70.141 53 210 3.1E-21 T 29-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SMALA_RS38480 774e4e6b280a249fa0807860686dc957 334 SUPERFAMILY SSF54919 57 203 1.83E-16 T 29-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SMALA_RS40235 934fe7a4b6338a17e1df77c96ca70e77 158 Gene3D G3DSA:1.10.10.10 6 150 2.8E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS40235 934fe7a4b6338a17e1df77c96ca70e77 158 SUPERFAMILY SSF46785 11 144 2.93E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS40235 934fe7a4b6338a17e1df77c96ca70e77 158 Pfam PF01638 HxlR-like helix-turn-helix 24 109 1.7E-18 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type SMALA_RS38895 991c5ceda09a74213e9cea83afd37fb5 395 Gene3D G3DSA:1.20.120.540 333 392 2.8E-6 T 29-03-2018 IPR027378 Cyclic nucleotide-regulated ion channel, N-terminal domain Reactome: R-HSA-159418|Reactome: R-HSA-879518 SMALA_RS38895 991c5ceda09a74213e9cea83afd37fb5 395 Gene3D G3DSA:1.20.1250.20 207 332 1.5E-16 T 29-03-2018 SMALA_RS38895 991c5ceda09a74213e9cea83afd37fb5 395 Pfam PF07690 Major Facilitator Superfamily 13 330 5.9E-20 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS38895 991c5ceda09a74213e9cea83afd37fb5 395 SUPERFAMILY SSF103473 11 383 1.13E-36 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS38895 991c5ceda09a74213e9cea83afd37fb5 395 Gene3D G3DSA:1.20.1250.20 4 195 6.8E-13 T 29-03-2018 SMALA_RS32785 76cf4bd90ca1e12d190a77da4e21fafe 281 Gene3D G3DSA:3.40.630.30 3 115 6.0E-11 T 29-03-2018 SMALA_RS32785 76cf4bd90ca1e12d190a77da4e21fafe 281 SUPERFAMILY SSF55729 18 112 2.66E-11 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS32785 76cf4bd90ca1e12d190a77da4e21fafe 281 Pfam PF00583 Acetyltransferase (GNAT) family 203 269 1.3E-9 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SMALA_RS32785 76cf4bd90ca1e12d190a77da4e21fafe 281 Pfam PF00583 Acetyltransferase (GNAT) family 23 92 3.0E-5 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SMALA_RS32785 76cf4bd90ca1e12d190a77da4e21fafe 281 SUPERFAMILY SSF55729 127 275 2.44E-20 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS32785 76cf4bd90ca1e12d190a77da4e21fafe 281 Gene3D G3DSA:3.40.630.30 122 279 3.1E-20 T 29-03-2018 SMALA_RS04345 cfb17b9d079b8079fba10c8be85edf4f 3415 Gene3D G3DSA:1.10.1200.10 3212 3321 1.2E-17 T 29-03-2018 SMALA_RS04345 cfb17b9d079b8079fba10c8be85edf4f 3415 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2336 2636 2.4E-106 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS04345 cfb17b9d079b8079fba10c8be85edf4f 3415 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 574 873 9.6E-121 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS04345 cfb17b9d079b8079fba10c8be85edf4f 3415 SUPERFAMILY SSF55048 2460 2520 8.24E-9 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS04345 cfb17b9d079b8079fba10c8be85edf4f 3415 SUPERFAMILY SSF55048 698 763 5.49E-13 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS04345 cfb17b9d079b8079fba10c8be85edf4f 3415 Gene3D G3DSA:3.40.366.10 570 707 8.7E-43 T 29-03-2018 SMALA_RS04345 cfb17b9d079b8079fba10c8be85edf4f 3415 Gene3D G3DSA:3.40.366.10 2332 2466 1.5E-38 T 29-03-2018 SMALA_RS04345 cfb17b9d079b8079fba10c8be85edf4f 3415 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1413 1593 6.6E-55 T 29-03-2018 SMALA_RS04345 cfb17b9d079b8079fba10c8be85edf4f 3415 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2958 3136 7.1E-47 T 29-03-2018 SMALA_RS04345 cfb17b9d079b8079fba10c8be85edf4f 3415 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 412 536 1.7E-14 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS04345 cfb17b9d079b8079fba10c8be85edf4f 3415 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2170 2298 1.6E-14 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS04345 cfb17b9d079b8079fba10c8be85edf4f 3415 Gene3D G3DSA:3.40.47.10 299 460 4.4E-63 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS04345 cfb17b9d079b8079fba10c8be85edf4f 3415 Gene3D G3DSA:3.40.47.10 2057 2218 7.5E-65 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS04345 cfb17b9d079b8079fba10c8be85edf4f 3415 SUPERFAMILY SSF51735 1411 1620 3.78E-41 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS04345 cfb17b9d079b8079fba10c8be85edf4f 3415 SMART SM00823 Phosphopantetheine attachment site 3244 3316 5.8E-30 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS04345 cfb17b9d079b8079fba10c8be85edf4f 3415 SMART SM00823 Phosphopantetheine attachment site 1700 1772 4.4E-29 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS04345 cfb17b9d079b8079fba10c8be85edf4f 3415 SUPERFAMILY SSF47336 1694 1806 6.94E-21 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS04345 cfb17b9d079b8079fba10c8be85edf4f 3415 SMART SM00825 Beta-ketoacyl synthase 1794 2220 1.9E-221 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS04345 cfb17b9d079b8079fba10c8be85edf4f 3415 SMART SM00825 Beta-ketoacyl synthase 36 462 4.5E-211 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS04345 cfb17b9d079b8079fba10c8be85edf4f 3415 SUPERFAMILY SSF51735 2954 3215 7.0E-50 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS04345 cfb17b9d079b8079fba10c8be85edf4f 3415 SUPERFAMILY SSF51735 1221 1399 4.72E-28 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS04345 cfb17b9d079b8079fba10c8be85edf4f 3415 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 292 409 1.6E-44 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS04345 cfb17b9d079b8079fba10c8be85edf4f 3415 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2050 2167 8.9E-46 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS04345 cfb17b9d079b8079fba10c8be85edf4f 3415 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1955 1971 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS04345 cfb17b9d079b8079fba10c8be85edf4f 3415 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1727 1742 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS04345 cfb17b9d079b8079fba10c8be85edf4f 3415 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3271 3286 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS04345 cfb17b9d079b8079fba10c8be85edf4f 3415 SUPERFAMILY SSF52151 570 699 2.09E-69 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS04345 cfb17b9d079b8079fba10c8be85edf4f 3415 SUPERFAMILY SSF52151 764 862 2.09E-69 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS04345 cfb17b9d079b8079fba10c8be85edf4f 3415 SUPERFAMILY SSF53901 1789 2164 7.5E-104 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS04345 cfb17b9d079b8079fba10c8be85edf4f 3415 Gene3D G3DSA:3.40.47.10 1785 2054 8.3E-83 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS04345 cfb17b9d079b8079fba10c8be85edf4f 3415 Gene3D G3DSA:3.40.47.10 26 296 2.1E-78 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS04345 cfb17b9d079b8079fba10c8be85edf4f 3415 SMART SM01294 3245 3312 6.9E-5 T 29-03-2018 SMALA_RS04345 cfb17b9d079b8079fba10c8be85edf4f 3415 SMART SM01294 1701 1768 5.7E-5 T 29-03-2018 SMALA_RS04345 cfb17b9d079b8079fba10c8be85edf4f 3415 Pfam PF14765 Polyketide synthase dehydratase 940 1213 5.7E-62 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS04345 cfb17b9d079b8079fba10c8be85edf4f 3415 SUPERFAMILY SSF51735 2742 2945 1.5E-40 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS04345 cfb17b9d079b8079fba10c8be85edf4f 3415 Pfam PF08990 Erythronolide synthase docking 2 26 2.0E-11 T 29-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 SMALA_RS04345 cfb17b9d079b8079fba10c8be85edf4f 3415 Gene3D G3DSA:3.40.366.10 2519 2642 4.2E-21 T 29-03-2018 SMALA_RS04345 cfb17b9d079b8079fba10c8be85edf4f 3415 Gene3D G3DSA:3.40.366.10 759 876 4.9E-26 T 29-03-2018 SMALA_RS04345 cfb17b9d079b8079fba10c8be85edf4f 3415 Gene3D G3DSA:3.40.50.720 2950 3209 3.1E-51 T 29-03-2018 SMALA_RS04345 cfb17b9d079b8079fba10c8be85edf4f 3415 Gene3D G3DSA:3.40.50.720 1408 1658 4.0E-43 T 29-03-2018 SMALA_RS04345 cfb17b9d079b8079fba10c8be85edf4f 3415 Pfam PF00550 Phosphopantetheine attachment site 1702 1759 1.7E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS04345 cfb17b9d079b8079fba10c8be85edf4f 3415 Pfam PF00550 Phosphopantetheine attachment site 3246 3310 2.6E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS04345 cfb17b9d079b8079fba10c8be85edf4f 3415 SUPERFAMILY SSF52151 2332 2461 7.32E-63 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS04345 cfb17b9d079b8079fba10c8be85edf4f 3415 SUPERFAMILY SSF52151 2527 2620 7.32E-63 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS04345 cfb17b9d079b8079fba10c8be85edf4f 3415 Gene3D G3DSA:3.30.70.250 2467 2518 9.2E-12 T 29-03-2018 SMALA_RS04345 cfb17b9d079b8079fba10c8be85edf4f 3415 Gene3D G3DSA:3.30.70.250 708 758 7.8E-17 T 29-03-2018 SMALA_RS04345 cfb17b9d079b8079fba10c8be85edf4f 3415 SUPERFAMILY SSF47336 3243 3323 7.07E-20 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS04345 cfb17b9d079b8079fba10c8be85edf4f 3415 Gene3D G3DSA:1.10.1200.10 1668 1778 1.9E-17 T 29-03-2018 SMALA_RS04345 cfb17b9d079b8079fba10c8be85edf4f 3415 SMART SM00826 940 1101 4.0E-81 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS04345 cfb17b9d079b8079fba10c8be85edf4f 3415 Pfam PF00698 Acyl transferase domain 572 891 2.6E-85 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS04345 cfb17b9d079b8079fba10c8be85edf4f 3415 Pfam PF00698 Acyl transferase domain 2334 2653 2.2E-76 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS04345 cfb17b9d079b8079fba10c8be85edf4f 3415 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 284 2.0E-85 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS04345 cfb17b9d079b8079fba10c8be85edf4f 3415 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1792 2042 2.8E-88 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS04345 cfb17b9d079b8079fba10c8be85edf4f 3415 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 197 213 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS04345 cfb17b9d079b8079fba10c8be85edf4f 3415 SUPERFAMILY SSF53901 31 406 9.81E-99 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS04345 cfb17b9d079b8079fba10c8be85edf4f 3415 Gene3D G3DSA:3.10.129.10 942 1064 3.8E-7 T 29-03-2018 SMALA_RS04345 cfb17b9d079b8079fba10c8be85edf4f 3415 Pfam PF08659 KR domain 1413 1591 1.5E-56 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS04345 cfb17b9d079b8079fba10c8be85edf4f 3415 Pfam PF08659 KR domain 2958 3134 6.6E-54 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS21625 49c652ca306191b6d816c5b911e967ac 138 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 45 87 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 SMALA_RS21625 49c652ca306191b6d816c5b911e967ac 138 SUPERFAMILY SSF46689 2 42 2.03E-10 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS21625 49c652ca306191b6d816c5b911e967ac 138 Pfam PF12833 Helix-turn-helix domain 14 91 3.8E-24 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS21625 49c652ca306191b6d816c5b911e967ac 138 SMART SM00342 8 91 4.7E-33 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS21625 49c652ca306191b6d816c5b911e967ac 138 SUPERFAMILY SSF46689 44 92 1.89E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS21625 49c652ca306191b6d816c5b911e967ac 138 Gene3D G3DSA:1.10.10.60 49 95 1.8E-16 T 29-03-2018 SMALA_RS21625 49c652ca306191b6d816c5b911e967ac 138 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 75 91 1.1E-6 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SMALA_RS21625 49c652ca306191b6d816c5b911e967ac 138 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 60 75 1.1E-6 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SMALA_RS21625 49c652ca306191b6d816c5b911e967ac 138 Gene3D G3DSA:1.10.10.60 3 48 6.1E-17 T 29-03-2018 SMALA_RS34105 4c2b86822df452a4a4f36c1b6417cd9b 2711 SUPERFAMILY SSF47336 2624 2698 5.23E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS34105 4c2b86822df452a4a4f36c1b6417cd9b 2711 SUPERFAMILY SSF53901 4 373 4.68E-87 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS34105 4c2b86822df452a4a4f36c1b6417cd9b 2711 SUPERFAMILY SSF53901 410 429 4.68E-87 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS34105 4c2b86822df452a4a4f36c1b6417cd9b 2711 Gene3D G3DSA:1.10.1200.10 2607 2701 1.3E-13 T 29-03-2018 SMALA_RS34105 4c2b86822df452a4a4f36c1b6417cd9b 2711 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 265 380 4.8E-33 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS34105 4c2b86822df452a4a4f36c1b6417cd9b 2711 Gene3D G3DSA:3.40.47.10 1 268 2.2E-78 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS34105 4c2b86822df452a4a4f36c1b6417cd9b 2711 Gene3D G3DSA:3.90.180.10 2213 2298 0.077 T 29-03-2018 SMALA_RS34105 4c2b86822df452a4a4f36c1b6417cd9b 2711 Gene3D G3DSA:3.30.70.250 807 852 3.7E-15 T 29-03-2018 SMALA_RS34105 4c2b86822df452a4a4f36c1b6417cd9b 2711 SMART SM00825 Beta-ketoacyl synthase 9 435 7.5E-176 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS34105 4c2b86822df452a4a4f36c1b6417cd9b 2711 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 169 185 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS34105 4c2b86822df452a4a4f36c1b6417cd9b 2711 SMART SM00826 1037 1196 6.1E-26 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS34105 4c2b86822df452a4a4f36c1b6417cd9b 2711 SMART SM01294 2629 2696 1.9E-4 T 29-03-2018 SMALA_RS34105 4c2b86822df452a4a4f36c1b6417cd9b 2711 Pfam PF14765 Polyketide synthase dehydratase 1037 1330 5.9E-51 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS34105 4c2b86822df452a4a4f36c1b6417cd9b 2711 SUPERFAMILY SSF50129 1968 2115 8.37E-30 T 29-03-2018 IPR011032 GroES-like SMALA_RS34105 4c2b86822df452a4a4f36c1b6417cd9b 2711 Gene3D G3DSA:3.40.47.10 271 433 6.7E-51 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS34105 4c2b86822df452a4a4f36c1b6417cd9b 2711 Gene3D G3DSA:3.40.366.10 853 971 5.2E-27 T 29-03-2018 SMALA_RS34105 4c2b86822df452a4a4f36c1b6417cd9b 2711 Gene3D G3DSA:3.10.129.10 1054 1154 1.5E-4 T 29-03-2018 SMALA_RS34105 4c2b86822df452a4a4f36c1b6417cd9b 2711 Gene3D G3DSA:3.40.366.10 665 806 8.1E-41 T 29-03-2018 SMALA_RS34105 4c2b86822df452a4a4f36c1b6417cd9b 2711 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2654 2669 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS34105 4c2b86822df452a4a4f36c1b6417cd9b 2711 SUPERFAMILY SSF51735 1730 1908 3.62E-14 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS34105 4c2b86822df452a4a4f36c1b6417cd9b 2711 SMART SM00823 Phosphopantetheine attachment site 2627 2700 1.4E-4 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS34105 4c2b86822df452a4a4f36c1b6417cd9b 2711 SUPERFAMILY SSF55048 792 854 1.03E-9 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS34105 4c2b86822df452a4a4f36c1b6417cd9b 2711 Pfam PF00550 Phosphopantetheine attachment site 2629 2694 2.5E-15 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS34105 4c2b86822df452a4a4f36c1b6417cd9b 2711 Pfam PF00698 Acyl transferase domain 668 949 5.3E-70 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS34105 4c2b86822df452a4a4f36c1b6417cd9b 2711 Pfam PF08242 Methyltransferase domain 1551 1651 3.0E-15 T 29-03-2018 IPR013217 Methyltransferase type 12 SMALA_RS34105 4c2b86822df452a4a4f36c1b6417cd9b 2711 SUPERFAMILY SSF53335 1511 1703 1.24E-28 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS34105 4c2b86822df452a4a4f36c1b6417cd9b 2711 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 7 256 7.5E-82 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS34105 4c2b86822df452a4a4f36c1b6417cd9b 2711 Pfam PF00107 Zinc-binding dehydrogenase 2117 2217 2.5E-23 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMALA_RS34105 4c2b86822df452a4a4f36c1b6417cd9b 2711 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 2106 2127 - T 29-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 SMALA_RS34105 4c2b86822df452a4a4f36c1b6417cd9b 2711 Gene3D G3DSA:3.40.50.720 2340 2563 1.1E-41 T 29-03-2018 SMALA_RS34105 4c2b86822df452a4a4f36c1b6417cd9b 2711 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 669 973 7.8E-105 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS34105 4c2b86822df452a4a4f36c1b6417cd9b 2711 SUPERFAMILY SSF51735 2345 2587 1.48E-38 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS34105 4c2b86822df452a4a4f36c1b6417cd9b 2711 SMART SM00829 1973 2294 3.7E-141 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS34105 4c2b86822df452a4a4f36c1b6417cd9b 2711 Gene3D G3DSA:3.40.50.720 2114 2212 1.9E-24 T 29-03-2018 SMALA_RS34105 4c2b86822df452a4a4f36c1b6417cd9b 2711 SUPERFAMILY SSF51735 2077 2234 1.48E-46 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS34105 4c2b86822df452a4a4f36c1b6417cd9b 2711 Gene3D G3DSA:3.90.180.10 1965 2113 1.1E-40 T 29-03-2018 SMALA_RS34105 4c2b86822df452a4a4f36c1b6417cd9b 2711 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2347 2527 2.8E-45 T 29-03-2018 SMALA_RS34105 4c2b86822df452a4a4f36c1b6417cd9b 2711 Gene3D G3DSA:3.40.50.150 1482 1721 9.0E-28 T 29-03-2018 SMALA_RS34105 4c2b86822df452a4a4f36c1b6417cd9b 2711 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 383 497 6.8E-16 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS34105 4c2b86822df452a4a4f36c1b6417cd9b 2711 Pfam PF08659 KR domain 2347 2525 8.0E-56 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS34105 4c2b86822df452a4a4f36c1b6417cd9b 2711 SUPERFAMILY SSF52151 858 952 4.71E-65 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS34105 4c2b86822df452a4a4f36c1b6417cd9b 2711 SUPERFAMILY SSF52151 665 794 4.71E-65 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS41455 5ae29935a408059958134fd4f3eb06ea 620 Gene3D G3DSA:2.60.40.420 6 193 2.6E-28 T 29-03-2018 IPR008972 Cupredoxin SMALA_RS41455 5ae29935a408059958134fd4f3eb06ea 620 SUPERFAMILY SSF49503 459 598 1.36E-19 T 29-03-2018 IPR008972 Cupredoxin SMALA_RS41455 5ae29935a408059958134fd4f3eb06ea 620 SUPERFAMILY SSF49503 201 338 2.84E-17 T 29-03-2018 IPR008972 Cupredoxin SMALA_RS41455 5ae29935a408059958134fd4f3eb06ea 620 Pfam PF07731 Multicopper oxidase 462 599 1.4E-22 T 29-03-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 SMALA_RS41455 5ae29935a408059958134fd4f3eb06ea 620 Gene3D G3DSA:2.60.40.420 194 391 3.4E-32 T 29-03-2018 IPR008972 Cupredoxin SMALA_RS41455 5ae29935a408059958134fd4f3eb06ea 620 Pfam PF07732 Multicopper oxidase 128 196 4.6E-6 T 29-03-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 SMALA_RS41455 5ae29935a408059958134fd4f3eb06ea 620 SUPERFAMILY SSF49503 128 197 2.62E-20 T 29-03-2018 IPR008972 Cupredoxin SMALA_RS41455 5ae29935a408059958134fd4f3eb06ea 620 SUPERFAMILY SSF49503 29 90 2.62E-20 T 29-03-2018 IPR008972 Cupredoxin SMALA_RS41455 5ae29935a408059958134fd4f3eb06ea 620 Gene3D G3DSA:2.60.40.420 431 601 1.4E-26 T 29-03-2018 IPR008972 Cupredoxin SMALA_RS09610 0379cd5fe4dfed0e6d2aac4b03a89cce 141 PRINTS PR00162 Rieske 2Fe-2S subunit signature 98 110 4.5E-10 T 29-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 SMALA_RS09610 0379cd5fe4dfed0e6d2aac4b03a89cce 141 PRINTS PR00162 Rieske 2Fe-2S subunit signature 78 89 4.5E-10 T 29-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 SMALA_RS09610 0379cd5fe4dfed0e6d2aac4b03a89cce 141 PRINTS PR00162 Rieske 2Fe-2S subunit signature 111 123 4.5E-10 T 29-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 SMALA_RS09610 0379cd5fe4dfed0e6d2aac4b03a89cce 141 Pfam PF00355 Rieske [2Fe-2S] domain 59 127 4.4E-18 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMALA_RS09610 0379cd5fe4dfed0e6d2aac4b03a89cce 141 Gene3D G3DSA:2.102.10.10 31 141 1.1E-24 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMALA_RS09610 0379cd5fe4dfed0e6d2aac4b03a89cce 141 SUPERFAMILY SSF50022 43 137 1.31E-29 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMALA_RS15950 70064ad80d9c0bba8593498679c4be89 391 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 14 125 2.6E-31 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS15950 70064ad80d9c0bba8593498679c4be89 391 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 129 224 1.0E-27 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 SMALA_RS15950 70064ad80d9c0bba8593498679c4be89 391 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 236 390 4.4E-49 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMALA_RS15950 70064ad80d9c0bba8593498679c4be89 391 PIRSF PIRSF016578 132 388 8.7E-23 T 29-03-2018 SMALA_RS15950 70064ad80d9c0bba8593498679c4be89 391 PIRSF PIRSF016578 8 99 7.7E-10 T 29-03-2018 SMALA_RS15950 70064ad80d9c0bba8593498679c4be89 391 SUPERFAMILY SSF47203 235 390 1.27E-57 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMALA_RS15950 70064ad80d9c0bba8593498679c4be89 391 Gene3D G3DSA:2.40.110.10 128 223 4.4E-39 T 29-03-2018 SMALA_RS15950 70064ad80d9c0bba8593498679c4be89 391 SUPERFAMILY SSF56645 13 248 2.62E-81 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMALA_RS15950 70064ad80d9c0bba8593498679c4be89 391 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 131 143 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 SMALA_RS15950 70064ad80d9c0bba8593498679c4be89 391 Gene3D G3DSA:1.20.140.10 224 390 8.7E-62 T 29-03-2018 SMALA_RS15950 70064ad80d9c0bba8593498679c4be89 391 Gene3D G3DSA:1.10.540.10 2 127 1.6E-33 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS15950 70064ad80d9c0bba8593498679c4be89 391 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 349 368 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 SMALA_RS42145 aeeea31ae23929ba40cb17c8ead1df35 236 Pfam PF00106 short chain dehydrogenase 10 195 1.9E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS42145 aeeea31ae23929ba40cb17c8ead1df35 236 SUPERFAMILY SSF51735 9 209 6.71E-50 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS42145 aeeea31ae23929ba40cb17c8ead1df35 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 3.5E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS42145 aeeea31ae23929ba40cb17c8ead1df35 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 3.5E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS42145 aeeea31ae23929ba40cb17c8ead1df35 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 3.5E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS42145 aeeea31ae23929ba40cb17c8ead1df35 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 3.5E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS42145 aeeea31ae23929ba40cb17c8ead1df35 236 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMALA_RS42145 aeeea31ae23929ba40cb17c8ead1df35 236 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 2.4E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS42145 aeeea31ae23929ba40cb17c8ead1df35 236 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 2.4E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS42145 aeeea31ae23929ba40cb17c8ead1df35 236 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 2.4E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS42145 aeeea31ae23929ba40cb17c8ead1df35 236 Gene3D G3DSA:3.40.50.720 7 233 1.3E-47 T 29-03-2018 SMALA_RS32330 e1f65ece5b5f6a538fc94bd59dff04a6 841 Pfam PF01588 Putative tRNA binding domain 48 153 1.2E-19 T 29-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 SMALA_RS32330 e1f65ece5b5f6a538fc94bd59dff04a6 841 SMART SM00896 746 839 8.3E-41 T 29-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 SMALA_RS32330 e1f65ece5b5f6a538fc94bd59dff04a6 841 Gene3D G3DSA:3.30.56.10 419 487 5.2E-20 T 29-03-2018 SMALA_RS32330 e1f65ece5b5f6a538fc94bd59dff04a6 841 SUPERFAMILY SSF56037 205 409 1.15E-63 T 29-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 SMALA_RS32330 e1f65ece5b5f6a538fc94bd59dff04a6 841 Pfam PF03147 Ferredoxin-fold anticodon binding domain 746 839 2.0E-24 T 29-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 SMALA_RS32330 e1f65ece5b5f6a538fc94bd59dff04a6 841 Gene3D G3DSA:3.30.70.380 743 839 5.6E-25 T 29-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 SMALA_RS32330 e1f65ece5b5f6a538fc94bd59dff04a6 841 SUPERFAMILY SSF54991 743 839 1.01E-25 T 29-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 SMALA_RS32330 e1f65ece5b5f6a538fc94bd59dff04a6 841 SUPERFAMILY SSF55681 483 599 2.14E-42 T 29-03-2018 SMALA_RS32330 e1f65ece5b5f6a538fc94bd59dff04a6 841 SUPERFAMILY SSF55681 629 732 2.14E-42 T 29-03-2018 SMALA_RS32330 e1f65ece5b5f6a538fc94bd59dff04a6 841 SUPERFAMILY SSF46955 421 491 2.47E-15 T 29-03-2018 IPR009061 Putative DNA-binding domain SMALA_RS32330 e1f65ece5b5f6a538fc94bd59dff04a6 841 SMART SM00874 420 487 3.7E-23 T 29-03-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 SMALA_RS32330 e1f65ece5b5f6a538fc94bd59dff04a6 841 Pfam PF03484 tRNA synthetase B5 domain 423 487 7.0E-18 T 29-03-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 SMALA_RS32330 e1f65ece5b5f6a538fc94bd59dff04a6 841 SUPERFAMILY SSF50249 45 204 2.94E-34 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMALA_RS32330 e1f65ece5b5f6a538fc94bd59dff04a6 841 Gene3D G3DSA:2.40.50.140 44 148 1.5E-42 T 29-03-2018 SMALA_RS32330 e1f65ece5b5f6a538fc94bd59dff04a6 841 Gene3D G3DSA:3.30.930.10 502 733 4.1E-41 T 29-03-2018 SMALA_RS32330 e1f65ece5b5f6a538fc94bd59dff04a6 841 SMART SM00873 220 404 5.5E-80 T 29-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 SMALA_RS32330 e1f65ece5b5f6a538fc94bd59dff04a6 841 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 839 4.0E-188 T 29-03-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 SMALA_RS32330 e1f65ece5b5f6a538fc94bd59dff04a6 841 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 833 40.408 T 29-03-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 SMALA_RS32330 e1f65ece5b5f6a538fc94bd59dff04a6 841 Pfam PF03483 B3/4 domain 220 404 2.3E-66 T 29-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 SMALA_RS32330 e1f65ece5b5f6a538fc94bd59dff04a6 841 Gene3D G3DSA:3.30.56.10 149 192 3.0E-8 T 29-03-2018 SMALA_RS32330 e1f65ece5b5f6a538fc94bd59dff04a6 841 Gene3D G3DSA:3.50.40.10 204 415 4.8E-82 T 29-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 SMALA_RS08720 860cc6e4798f0d778c99ec1bce805b23 551 Pfam PF00117 Glutamine amidotransferase class-I 302 536 1.0E-46 T 29-03-2018 IPR017926 Glutamine amidotransferase SMALA_RS08720 860cc6e4798f0d778c99ec1bce805b23 551 Pfam PF06418 CTP synthase N-terminus 4 267 1.2E-122 T 29-03-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 SMALA_RS08720 860cc6e4798f0d778c99ec1bce805b23 551 Hamap MF_01227 CTP synthase [pyrG]. 3 541 50.33 T 29-03-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 SMALA_RS08720 860cc6e4798f0d778c99ec1bce805b23 551 SUPERFAMILY SSF52540 3 267 2.6E-118 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS08720 860cc6e4798f0d778c99ec1bce805b23 551 Gene3D G3DSA:3.40.50.880 287 544 1.4E-64 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS08720 860cc6e4798f0d778c99ec1bce805b23 551 SUPERFAMILY SSF52317 289 538 8.86E-68 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS08720 860cc6e4798f0d778c99ec1bce805b23 551 TIGRFAM TIGR00337 PyrG: CTP synthase 2 536 1.7E-229 T 29-03-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 SMALA_RS08720 860cc6e4798f0d778c99ec1bce805b23 551 Gene3D G3DSA:3.40.50.300 1 286 1.1E-127 T 29-03-2018 SMALA_RS17080 06ff6a04975d3426ba89ac3a917a4507 222 Pfam PF00072 Response regulator receiver domain 4 114 1.6E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS17080 06ff6a04975d3426ba89ac3a917a4507 222 Gene3D G3DSA:1.10.10.10 125 216 5.6E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS17080 06ff6a04975d3426ba89ac3a917a4507 222 SMART SM00421 149 206 8.9E-21 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS17080 06ff6a04975d3426ba89ac3a917a4507 222 SUPERFAMILY SSF46894 142 213 7.48E-19 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS17080 06ff6a04975d3426ba89ac3a917a4507 222 ProSitePatterns PS00622 LuxR-type HTH domain signature. 166 193 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS17080 06ff6a04975d3426ba89ac3a917a4507 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 182 2.0E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS17080 06ff6a04975d3426ba89ac3a917a4507 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 152 166 2.0E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS17080 06ff6a04975d3426ba89ac3a917a4507 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 182 194 2.0E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS17080 06ff6a04975d3426ba89ac3a917a4507 222 SUPERFAMILY SSF52172 2 131 2.13E-31 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS17080 06ff6a04975d3426ba89ac3a917a4507 222 Gene3D G3DSA:3.40.50.2300 1 124 3.5E-32 T 29-03-2018 SMALA_RS17080 06ff6a04975d3426ba89ac3a917a4507 222 Pfam PF00196 Bacterial regulatory proteins, luxR family 151 206 1.0E-15 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS17080 06ff6a04975d3426ba89ac3a917a4507 222 SMART SM00448 2 114 6.6E-28 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS22370 a54dc65eeb770bb9fae13d9c2707e8ad 428 SUPERFAMILY SSF51556 76 366 8.75E-43 T 29-03-2018 IPR032466 Metal-dependent hydrolase SMALA_RS22370 a54dc65eeb770bb9fae13d9c2707e8ad 428 SUPERFAMILY SSF51338 27 95 2.27E-6 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS22370 a54dc65eeb770bb9fae13d9c2707e8ad 428 Gene3D G3DSA:3.20.20.140 55 356 1.5E-26 T 29-03-2018 SMALA_RS36685 c700932c2971abe2b3dc3e71b5ea061b 256 SUPERFAMILY SSF48452 95 252 3.23E-39 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS36685 c700932c2971abe2b3dc3e71b5ea061b 256 Pfam PF03704 Bacterial transcriptional activator domain 99 244 2.5E-46 T 29-03-2018 IPR005158 Bacterial transcriptional activator domain SMALA_RS36685 c700932c2971abe2b3dc3e71b5ea061b 256 Pfam PF00486 Transcriptional regulatory protein, C terminal 28 92 8.2E-9 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS36685 c700932c2971abe2b3dc3e71b5ea061b 256 SMART SM00862 15 92 5.3E-8 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS36685 c700932c2971abe2b3dc3e71b5ea061b 256 SMART SM01043 99 244 6.9E-46 T 29-03-2018 IPR005158 Bacterial transcriptional activator domain SMALA_RS36685 c700932c2971abe2b3dc3e71b5ea061b 256 Gene3D G3DSA:1.10.10.10 1 95 4.9E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS36685 c700932c2971abe2b3dc3e71b5ea061b 256 SUPERFAMILY SSF46894 3 92 1.62E-13 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS36685 c700932c2971abe2b3dc3e71b5ea061b 256 Gene3D G3DSA:1.25.40.10 96 255 5.8E-24 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS15565 0bfaa6d3470bd66d601cfcccd06ed29a 452 Gene3D G3DSA:3.40.190.10 57 230 1.9E-31 T 29-03-2018 SMALA_RS15565 0bfaa6d3470bd66d601cfcccd06ed29a 452 Gene3D G3DSA:3.40.190.10 231 393 9.3E-11 T 29-03-2018 SMALA_RS15565 0bfaa6d3470bd66d601cfcccd06ed29a 452 Pfam PF01547 Bacterial extracellular solute-binding protein 65 360 1.8E-23 T 29-03-2018 IPR006059 Solute-binding family 1 GO:0006810 SMALA_RS15565 0bfaa6d3470bd66d601cfcccd06ed29a 452 SUPERFAMILY SSF53850 53 451 4.73E-55 T 29-03-2018 SMALA_RS12045 19cf82ce2a4cb84093f41481571c3205 297 SUPERFAMILY SSF51735 9 166 8.22E-37 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS12045 19cf82ce2a4cb84093f41481571c3205 297 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 172 286 7.7E-15 T 29-03-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 SMALA_RS12045 19cf82ce2a4cb84093f41481571c3205 297 PIRSF PIRSF000103 2 295 9.3E-72 T 29-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 SMALA_RS12045 19cf82ce2a4cb84093f41481571c3205 297 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 10 165 1.7E-34 T 29-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 SMALA_RS12045 19cf82ce2a4cb84093f41481571c3205 297 Gene3D G3DSA:1.10.1040.10 177 291 2.5E-18 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMALA_RS12045 19cf82ce2a4cb84093f41481571c3205 297 SUPERFAMILY SSF48179 172 288 3.29E-24 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMALA_RS12045 19cf82ce2a4cb84093f41481571c3205 297 Gene3D G3DSA:3.40.50.720 1 176 2.9E-29 T 29-03-2018 SMALA_RS02525 62b2f2c4de90ab270f15914a5665e65b 309 Gene3D G3DSA:3.40.190.10 86 173 6.1E-11 T 29-03-2018 SMALA_RS02525 62b2f2c4de90ab270f15914a5665e65b 309 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 7.2E-20 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS02525 62b2f2c4de90ab270f15914a5665e65b 309 SUPERFAMILY SSF46785 2 83 3.18E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS02525 62b2f2c4de90ab270f15914a5665e65b 309 Pfam PF03466 LysR substrate binding domain 102 292 7.6E-14 T 29-03-2018 IPR005119 LysR, substrate-binding SMALA_RS02525 62b2f2c4de90ab270f15914a5665e65b 309 Gene3D G3DSA:3.40.190.10 174 266 1.7E-4 T 29-03-2018 SMALA_RS02525 62b2f2c4de90ab270f15914a5665e65b 309 SUPERFAMILY SSF53850 101 297 1.84E-19 T 29-03-2018 SMALA_RS02525 62b2f2c4de90ab270f15914a5665e65b 309 Gene3D G3DSA:1.10.10.10 1 83 1.6E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS02525 62b2f2c4de90ab270f15914a5665e65b 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.4E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS02525 62b2f2c4de90ab270f15914a5665e65b 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.4E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS02525 62b2f2c4de90ab270f15914a5665e65b 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.4E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS05860 f72400400c0f718013064622d7785ce3 112 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 13 28 2.9E-8 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS05860 f72400400c0f718013064622d7785ce3 112 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 45 60 2.9E-8 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS05860 f72400400c0f718013064622d7785ce3 112 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 2.9E-8 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS05860 f72400400c0f718013064622d7785ce3 112 Gene3D G3DSA:1.10.10.10 6 96 2.9E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS05860 f72400400c0f718013064622d7785ce3 112 SMART SM00418 11 89 1.9E-21 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS05860 f72400400c0f718013064622d7785ce3 112 Pfam PF01022 Bacterial regulatory protein, arsR family 18 63 5.7E-11 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS05860 f72400400c0f718013064622d7785ce3 112 SUPERFAMILY SSF46785 3 88 9.85E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS09370 ea4c63ec2a9b6343f8fe590ca419abec 269 Gene3D G3DSA:3.40.50.720 3 230 2.2E-38 T 29-03-2018 SMALA_RS09370 ea4c63ec2a9b6343f8fe590ca419abec 269 Pfam PF01370 NAD dependent epimerase/dehydratase family 7 166 1.7E-22 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 SMALA_RS09370 ea4c63ec2a9b6343f8fe590ca419abec 269 SUPERFAMILY SSF51735 1 238 7.28E-46 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS39405 8a3667567d1dda6e65a6f3d4f8c259e6 596 Gene3D G3DSA:1.10.3720.10 331 592 4.4E-39 T 29-03-2018 SMALA_RS39405 8a3667567d1dda6e65a6f3d4f8c259e6 596 Gene3D G3DSA:1.10.3720.10 37 313 6.3E-36 T 29-03-2018 SMALA_RS39405 8a3667567d1dda6e65a6f3d4f8c259e6 596 SUPERFAMILY SSF161098 328 585 4.95E-49 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS39405 8a3667567d1dda6e65a6f3d4f8c259e6 596 SUPERFAMILY SSF161098 38 309 5.14E-48 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS39405 8a3667567d1dda6e65a6f3d4f8c259e6 596 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 416 585 2.3E-14 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS39405 8a3667567d1dda6e65a6f3d4f8c259e6 596 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 107 305 2.9E-12 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS06315 e40f6457343ba03c38918316a3c63249 414 Pfam PF00155 Aminotransferase class I and II 52 393 4.6E-73 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMALA_RS06315 e40f6457343ba03c38918316a3c63249 414 Gene3D G3DSA:3.90.1150.10 294 404 2.6E-24 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS06315 e40f6457343ba03c38918316a3c63249 414 Gene3D G3DSA:3.40.640.10 64 134 2.2E-4 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS06315 e40f6457343ba03c38918316a3c63249 414 SUPERFAMILY SSF53383 44 400 8.55E-113 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS06315 e40f6457343ba03c38918316a3c63249 414 Gene3D G3DSA:3.40.640.10 135 293 2.1E-56 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS06315 e40f6457343ba03c38918316a3c63249 414 TIGRFAM TIGR01821 5aminolev_synth: 5-aminolevulinic acid synthase 16 403 5.4E-162 T 29-03-2018 IPR010961 Tetrapyrrole biosynthesis, 5-aminolevulinic acid synthase GO:0003870|GO:0030170|GO:0033014 KEGG: 00260+2.3.1.37|KEGG: 00860+2.3.1.37|MetaCyc: PWY-5189|MetaCyc: PWY-7536|Reactome: R-HSA-189451 SMALA_RS06150 0cbf672286cfc4417910e5c3d95f95fe 252 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 13 191 6.5E-4 T 29-03-2018 SMALA_RS06150 0cbf672286cfc4417910e5c3d95f95fe 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 5.5E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS06150 0cbf672286cfc4417910e5c3d95f95fe 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 5.5E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS06150 0cbf672286cfc4417910e5c3d95f95fe 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 5.5E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS06150 0cbf672286cfc4417910e5c3d95f95fe 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 5.5E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS06150 0cbf672286cfc4417910e5c3d95f95fe 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 89 100 5.5E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS06150 0cbf672286cfc4417910e5c3d95f95fe 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 5.5E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS06150 0cbf672286cfc4417910e5c3d95f95fe 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 89 100 3.2E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS06150 0cbf672286cfc4417910e5c3d95f95fe 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 148 3.2E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS06150 0cbf672286cfc4417910e5c3d95f95fe 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 3.2E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS06150 0cbf672286cfc4417910e5c3d95f95fe 252 SUPERFAMILY SSF51735 13 251 1.05E-69 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS06150 0cbf672286cfc4417910e5c3d95f95fe 252 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 147 175 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMALA_RS06150 0cbf672286cfc4417910e5c3d95f95fe 252 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 21 250 6.3E-52 T 29-03-2018 SMALA_RS06150 0cbf672286cfc4417910e5c3d95f95fe 252 Gene3D G3DSA:3.40.50.720 2 252 1.4E-65 T 29-03-2018 SMALA_RS10770 30efa91401edd476f78a0e6cd0154b27 169 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 55 61 - T 29-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 SMALA_RS10770 30efa91401edd476f78a0e6cd0154b27 169 SUPERFAMILY SSF50324 4 159 1.31E-55 T 29-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 SMALA_RS10770 30efa91401edd476f78a0e6cd0154b27 169 Pfam PF00719 Inorganic pyrophosphatase 8 159 1.8E-52 T 29-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 SMALA_RS10770 30efa91401edd476f78a0e6cd0154b27 169 Gene3D G3DSA:3.90.80.10 1 165 3.8E-51 T 29-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 SMALA_RS10770 30efa91401edd476f78a0e6cd0154b27 169 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 4 161 31.978 T 29-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 SMALA_RS32505 434c906d89f3dfa0b9ea2474d59ec217 398 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 8 16 - T 29-03-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SMALA_RS32505 434c906d89f3dfa0b9ea2474d59ec217 398 TIGRFAM TIGR00032 argG: argininosuccinate synthase 4 392 2.4E-145 T 29-03-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SMALA_RS32505 434c906d89f3dfa0b9ea2474d59ec217 398 Gene3D G3DSA:3.40.50.620 3 161 4.1E-25 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS32505 434c906d89f3dfa0b9ea2474d59ec217 398 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 117 128 - T 29-03-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SMALA_RS32505 434c906d89f3dfa0b9ea2474d59ec217 398 Gene3D G3DSA:3.90.1260.10 162 352 7.0E-75 T 29-03-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SMALA_RS32505 434c906d89f3dfa0b9ea2474d59ec217 398 SUPERFAMILY SSF52402 3 166 8.6E-42 T 29-03-2018 SMALA_RS32505 434c906d89f3dfa0b9ea2474d59ec217 398 SUPERFAMILY SSF69864 171 395 1.57E-83 T 29-03-2018 SMALA_RS32505 434c906d89f3dfa0b9ea2474d59ec217 398 Pfam PF00764 Arginosuccinate synthase 6 391 6.1E-183 T 29-03-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SMALA_RS32505 434c906d89f3dfa0b9ea2474d59ec217 398 Hamap MF_00005 Argininosuccinate synthase [argG]. 2 396 51.398 T 29-03-2018 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SMALA_RS32505 434c906d89f3dfa0b9ea2474d59ec217 398 Gene3D G3DSA:1.20.5.470 362 394 1.6E-7 T 29-03-2018 SMALA_RS39400 ec94f6946d2d955129cd513d9c87cdd4 377 Pfam PF00005 ABC transporter 34 184 5.4E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS39400 ec94f6946d2d955129cd513d9c87cdd4 377 SMART SM00382 41 234 1.3E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS39400 ec94f6946d2d955129cd513d9c87cdd4 377 Gene3D G3DSA:2.40.50.140 311 367 2.6E-4 T 29-03-2018 SMALA_RS39400 ec94f6946d2d955129cd513d9c87cdd4 377 Gene3D G3DSA:3.40.50.300 1 262 6.0E-65 T 29-03-2018 SMALA_RS39400 ec94f6946d2d955129cd513d9c87cdd4 377 SUPERFAMILY SSF50331 260 373 3.16E-18 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal SMALA_RS39400 ec94f6946d2d955129cd513d9c87cdd4 377 SUPERFAMILY SSF52540 1 265 1.36E-79 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS39400 ec94f6946d2d955129cd513d9c87cdd4 377 Pfam PF08402 TOBE domain 301 373 3.0E-10 T 29-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 SMALA_RS39400 ec94f6946d2d955129cd513d9c87cdd4 377 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS39400 ec94f6946d2d955129cd513d9c87cdd4 377 Gene3D G3DSA:2.40.50.100 263 310 1.8E-6 T 29-03-2018 SMALA_RS07120 6f54c62ff10533fdfa467ae644fa45ca 317 Gene3D G3DSA:3.40.50.1820 3 317 3.3E-38 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS07120 6f54c62ff10533fdfa467ae644fa45ca 317 SUPERFAMILY SSF53474 5 171 6.51E-36 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS07120 6f54c62ff10533fdfa467ae644fa45ca 317 SUPERFAMILY SSF53474 198 317 6.51E-36 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS07120 6f54c62ff10533fdfa467ae644fa45ca 317 Pfam PF12146 Serine aminopeptidase, S33 33 301 1.1E-48 T 29-03-2018 IPR022742 Serine aminopeptidase, S33 SMALA_RS32145 960cfefb9da2d612b6c5a8bfd79d5a40 274 Pfam PF13350 Tyrosine phosphatase family 16 272 2.2E-62 T 29-03-2018 IPR026893 Tyrosine/serine-protein phosphatase IphP-type SMALA_RS32145 960cfefb9da2d612b6c5a8bfd79d5a40 274 Gene3D G3DSA:3.90.190.10 28 204 5.7E-21 T 29-03-2018 IPR029021 Protein-tyrosine phosphatase-like SMALA_RS32145 960cfefb9da2d612b6c5a8bfd79d5a40 274 SUPERFAMILY SSF52799 19 272 6.16E-48 T 29-03-2018 IPR029021 Protein-tyrosine phosphatase-like SMALA_RS29190 a34af2d43f02544e6ece7c6da0d26c88 417 SMART SM00304 144 197 2.4E-12 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMALA_RS29190 a34af2d43f02544e6ece7c6da0d26c88 417 Pfam PF00672 HAMP domain 145 193 1.7E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMALA_RS29190 a34af2d43f02544e6ece7c6da0d26c88 417 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 310 416 1.2E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS29190 a34af2d43f02544e6ece7c6da0d26c88 417 PRINTS PR00344 Bacterial sensor protein C-terminal signature 362 372 1.5E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS29190 a34af2d43f02544e6ece7c6da0d26c88 417 PRINTS PR00344 Bacterial sensor protein C-terminal signature 379 397 1.5E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS29190 a34af2d43f02544e6ece7c6da0d26c88 417 PRINTS PR00344 Bacterial sensor protein C-terminal signature 403 416 1.5E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS29190 a34af2d43f02544e6ece7c6da0d26c88 417 SUPERFAMILY SSF158472 145 194 1.44E-8 T 29-03-2018 SMALA_RS29190 a34af2d43f02544e6ece7c6da0d26c88 417 SUPERFAMILY SSF47384 181 263 1.04E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS29190 a34af2d43f02544e6ece7c6da0d26c88 417 Gene3D G3DSA:1.10.287.130 203 260 4.0E-12 T 29-03-2018 SMALA_RS29190 a34af2d43f02544e6ece7c6da0d26c88 417 Gene3D G3DSA:3.30.565.10 266 417 1.4E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS29190 a34af2d43f02544e6ece7c6da0d26c88 417 SMART SM00388 198 264 2.3E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS29190 a34af2d43f02544e6ece7c6da0d26c88 417 Gene3D G3DSA:3.30.450.20 145 202 7.2E-4 T 29-03-2018 SMALA_RS29190 a34af2d43f02544e6ece7c6da0d26c88 417 Pfam PF00512 His Kinase A (phospho-acceptor) domain 199 263 7.1E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS29190 a34af2d43f02544e6ece7c6da0d26c88 417 SMART SM00387 306 417 1.1E-24 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS29190 a34af2d43f02544e6ece7c6da0d26c88 417 SUPERFAMILY SSF55874 267 417 6.94E-33 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS07115 e0b85bdd2f1f6faa3d0c4c78a1905c31 307 Pfam PF02779 Transketolase, pyrimidine binding domain 3 161 5.3E-19 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain SMALA_RS07115 e0b85bdd2f1f6faa3d0c4c78a1905c31 307 Gene3D G3DSA:3.40.50.970 24 173 2.0E-26 T 29-03-2018 SMALA_RS07115 e0b85bdd2f1f6faa3d0c4c78a1905c31 307 SUPERFAMILY SSF52922 171 302 1.7E-9 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMALA_RS07115 e0b85bdd2f1f6faa3d0c4c78a1905c31 307 SUPERFAMILY SSF52518 3 167 3.91E-31 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold SMALA_RS07115 e0b85bdd2f1f6faa3d0c4c78a1905c31 307 SMART SM00861 2 168 7.3E-16 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain SMALA_RS07115 e0b85bdd2f1f6faa3d0c4c78a1905c31 307 Gene3D G3DSA:3.40.50.920 174 307 1.8E-15 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMALA_RS33130 2452a7b53816902f7b61f0d488e51aee 90 Gene3D G3DSA:3.90.940.10 11 87 3.1E-21 T 29-03-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 SMALA_RS33130 2452a7b53816902f7b61f0d488e51aee 90 SMART SM01409 18 82 2.2E-14 T 29-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 SMALA_RS33130 2452a7b53816902f7b61f0d488e51aee 90 SUPERFAMILY SSF63562 11 86 1.06E-24 T 29-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 SMALA_RS33130 2452a7b53816902f7b61f0d488e51aee 90 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 12 80 8.5E-22 T 29-03-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMALA_RS33130 2452a7b53816902f7b61f0d488e51aee 90 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 11 83 14.945 T 29-03-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMALA_RS33130 2452a7b53816902f7b61f0d488e51aee 90 Pfam PF01192 RNA polymerase Rpb6 18 80 1.0E-14 T 29-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 SMALA_RS11530 faac38b737909d188d24b09a03b45a39 310 Gene3D G3DSA:1.10.10.60 196 258 2.4E-14 T 29-03-2018 SMALA_RS11530 faac38b737909d188d24b09a03b45a39 310 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 255 297 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 SMALA_RS11530 faac38b737909d188d24b09a03b45a39 310 Pfam PF12852 Cupin 4 185 7.6E-36 T 29-03-2018 IPR032783 AraC-type transcription regulator, ligand-binding domain SMALA_RS11530 faac38b737909d188d24b09a03b45a39 310 Gene3D G3DSA:2.60.120.280 12 186 1.8E-8 T 29-03-2018 SMALA_RS11530 faac38b737909d188d24b09a03b45a39 310 Pfam PF12833 Helix-turn-helix domain 224 301 5.8E-20 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS11530 faac38b737909d188d24b09a03b45a39 310 Gene3D G3DSA:1.10.10.60 259 306 4.9E-11 T 29-03-2018 SMALA_RS11530 faac38b737909d188d24b09a03b45a39 310 SUPERFAMILY SSF46689 254 302 3.54E-10 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS11530 faac38b737909d188d24b09a03b45a39 310 SMART SM00342 218 301 2.1E-30 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS11530 faac38b737909d188d24b09a03b45a39 310 SUPERFAMILY SSF46689 201 252 5.27E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS09955 90492f72626bbb725dca1cd5b4885169 272 SUPERFAMILY SSF51366 8 249 3.38E-80 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 SMALA_RS09955 90492f72626bbb725dca1cd5b4885169 272 Pfam PF00290 Tryptophan synthase alpha chain 13 267 4.7E-78 T 29-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 SMALA_RS09955 90492f72626bbb725dca1cd5b4885169 272 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 18 267 34.246 T 29-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 SMALA_RS09955 90492f72626bbb725dca1cd5b4885169 272 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 52 65 - T 29-03-2018 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 SMALA_RS09955 90492f72626bbb725dca1cd5b4885169 272 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 15 264 1.3E-69 T 29-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 SMALA_RS09955 90492f72626bbb725dca1cd5b4885169 272 Gene3D G3DSA:3.20.20.70 7 272 2.1E-76 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS00935 8b52eb2fc03e611f552fd39a2443edfd 376 SUPERFAMILY SSF51679 19 369 2.36E-78 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS00935 8b52eb2fc03e611f552fd39a2443edfd 376 Pfam PF00296 Luciferase-like monooxygenase 10 339 7.1E-75 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS00935 8b52eb2fc03e611f552fd39a2443edfd 376 Gene3D G3DSA:3.20.20.30 1 372 3.1E-79 T 29-03-2018 SMALA_RS35255 816fec649045800f42e19fd14d5c7957 797 Hamap MF_01403 Probable phosphoketolase. 12 797 40.461 T 29-03-2018 IPR023962 Probable phosphoketolase SMALA_RS35255 816fec649045800f42e19fd14d5c7957 797 Gene3D G3DSA:3.40.50.920 613 797 1.2E-76 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMALA_RS35255 816fec649045800f42e19fd14d5c7957 797 Gene3D G3DSA:3.40.50.970 386 607 1.1E-30 T 29-03-2018 SMALA_RS35255 816fec649045800f42e19fd14d5c7957 797 Pfam PF03894 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase 406 582 2.0E-85 T 29-03-2018 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 SMALA_RS35255 816fec649045800f42e19fd14d5c7957 797 ProSitePatterns PS60002 Phosphoketolase signature 1. 151 157 - T 29-03-2018 IPR019790 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, conserved site GO:0005975|GO:0016832 SMALA_RS35255 816fec649045800f42e19fd14d5c7957 797 Pfam PF09363 XFP C-terminal domain 593 795 2.8E-84 T 29-03-2018 IPR018969 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, C-terminal GO:0005975|GO:0016832 SMALA_RS35255 816fec649045800f42e19fd14d5c7957 797 Pfam PF09364 XFP N-terminal domain 16 391 1.9E-177 T 29-03-2018 IPR018970 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, N-terminal SMALA_RS35255 816fec649045800f42e19fd14d5c7957 797 PIRSF PIRSF017245 4 797 0.0 T 29-03-2018 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 SMALA_RS35255 816fec649045800f42e19fd14d5c7957 797 SUPERFAMILY SSF52518 384 595 4.94E-21 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold SMALA_RS35255 816fec649045800f42e19fd14d5c7957 797 SUPERFAMILY SSF52518 8 375 1.07E-72 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold SMALA_RS35255 816fec649045800f42e19fd14d5c7957 797 ProSitePatterns PS60003 Phosphoketolase signature 2. 164 182 - T 29-03-2018 IPR019789 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, thiamine diphosphate binding site GO:0005975|GO:0016832 SMALA_RS35255 816fec649045800f42e19fd14d5c7957 797 Gene3D G3DSA:3.40.50.970 7 385 1.6E-86 T 29-03-2018 SMALA_RS09805 ca8834d58149375ff55bdd76b1ba2ee8 410 Pfam PF13458 Periplasmic binding protein 40 398 1.1E-45 T 29-03-2018 IPR028081 Leucine-binding protein domain SMALA_RS09805 ca8834d58149375ff55bdd76b1ba2ee8 410 SUPERFAMILY SSF53822 40 403 3.1E-72 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SMALA_RS09805 ca8834d58149375ff55bdd76b1ba2ee8 410 Gene3D G3DSA:3.40.50.2300 38 387 5.9E-56 T 29-03-2018 SMALA_RS32170 8beb94011dd669502ac4900d05840ff3 302 Gene3D G3DSA:3.80.30.20 10 142 1.7E-5 T 29-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe SMALA_RS32170 8beb94011dd669502ac4900d05840ff3 302 SUPERFAMILY SSF102114 13 240 1.08E-14 T 29-03-2018 SMALA_RS17515 a4bfc610177ea6b488817ea774a91246 436 Gene3D G3DSA:3.40.50.1100 112 221 4.3E-17 T 29-03-2018 SMALA_RS17515 a4bfc610177ea6b488817ea774a91246 436 TIGRFAM TIGR00260 thrC: threonine synthase 79 409 2.3E-80 T 29-03-2018 IPR004450 Threonine synthase-like SMALA_RS17515 a4bfc610177ea6b488817ea774a91246 436 Gene3D G3DSA:3.40.50.1100 223 420 9.8E-39 T 29-03-2018 SMALA_RS17515 a4bfc610177ea6b488817ea774a91246 436 SUPERFAMILY SSF53686 20 418 8.91E-87 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMALA_RS17515 a4bfc610177ea6b488817ea774a91246 436 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 100 404 4.3E-61 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMALA_RS30590 6ab4e3fc6eab3b1e3b35e24c13f43417 198 SUPERFAMILY SSF51182 69 175 1.43E-19 T 29-03-2018 IPR011051 RmlC-like cupin domain SMALA_RS30590 6ab4e3fc6eab3b1e3b35e24c13f43417 198 SMART SM00530 7 62 4.5E-16 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS30590 6ab4e3fc6eab3b1e3b35e24c13f43417 198 Pfam PF07883 Cupin domain 118 173 9.1E-12 T 29-03-2018 IPR013096 Cupin 2, conserved barrel SMALA_RS30590 6ab4e3fc6eab3b1e3b35e24c13f43417 198 Pfam PF13560 Helix-turn-helix domain 5 61 3.6E-16 T 29-03-2018 SMALA_RS30590 6ab4e3fc6eab3b1e3b35e24c13f43417 198 SUPERFAMILY SSF47413 3 68 8.58E-16 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS30590 6ab4e3fc6eab3b1e3b35e24c13f43417 198 Gene3D G3DSA:2.60.120.10 66 184 6.6E-16 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SMALA_RS30590 6ab4e3fc6eab3b1e3b35e24c13f43417 198 Gene3D G3DSA:1.10.260.40 6 65 2.7E-18 T 29-03-2018 SMALA_RS30765 c0d9f47d20b9d7b255134aa479237a6b 467 Pfam PF01979 Amidohydrolase family 56 439 1.5E-27 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 SMALA_RS30765 c0d9f47d20b9d7b255134aa479237a6b 467 SUPERFAMILY SSF51556 60 388 3.36E-104 T 29-03-2018 IPR032466 Metal-dependent hydrolase SMALA_RS30765 c0d9f47d20b9d7b255134aa479237a6b 467 Gene3D G3DSA:3.20.20.140 76 409 5.7E-99 T 29-03-2018 SMALA_RS30765 c0d9f47d20b9d7b255134aa479237a6b 467 TIGRFAM TIGR02033 D-hydantoinase: dihydropyrimidinase 6 460 1.5E-167 T 29-03-2018 IPR011778 Hydantoinase/dihydropyrimidinase GO:0005737 Reactome: R-HSA-399956 SMALA_RS30765 c0d9f47d20b9d7b255134aa479237a6b 467 Gene3D G3DSA:2.30.40.10 4 75 7.4E-17 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS30765 c0d9f47d20b9d7b255134aa479237a6b 467 SUPERFAMILY SSF51338 5 70 1.94E-7 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS30765 c0d9f47d20b9d7b255134aa479237a6b 467 SUPERFAMILY SSF51338 362 462 9.6E-33 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS00660 5961b68865a274aeca1abdf6531a8e56 228 SUPERFAMILY SSF46689 5 83 9.23E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS00660 5961b68865a274aeca1abdf6531a8e56 228 Gene3D G3DSA:1.10.357.10 2 221 1.6E-27 T 29-03-2018 SMALA_RS00660 5961b68865a274aeca1abdf6531a8e56 228 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 63 6.4E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS05730 300e87d502d2ad7241fc5bd52cada473 122 SUPERFAMILY SSF54593 6 120 4.93E-9 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS05730 300e87d502d2ad7241fc5bd52cada473 122 Gene3D G3DSA:3.10.180.10 4 121 1.4E-10 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS31660 16a90d36abce0a73d19e53a40c138edf 293 Pfam PF03466 LysR substrate binding domain 88 286 3.8E-43 T 29-03-2018 IPR005119 LysR, substrate-binding SMALA_RS31660 16a90d36abce0a73d19e53a40c138edf 293 Gene3D G3DSA:3.40.190.10 87 179 7.1E-29 T 29-03-2018 SMALA_RS31660 16a90d36abce0a73d19e53a40c138edf 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.9E-22 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS31660 16a90d36abce0a73d19e53a40c138edf 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.6E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS31660 16a90d36abce0a73d19e53a40c138edf 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.6E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS31660 16a90d36abce0a73d19e53a40c138edf 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.6E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS31660 16a90d36abce0a73d19e53a40c138edf 293 SUPERFAMILY SSF53850 88 287 8.02E-40 T 29-03-2018 SMALA_RS31660 16a90d36abce0a73d19e53a40c138edf 293 Gene3D G3DSA:1.10.10.10 1 83 6.6E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS31660 16a90d36abce0a73d19e53a40c138edf 293 Gene3D G3DSA:3.40.190.10 180 267 5.2E-21 T 29-03-2018 SMALA_RS31660 16a90d36abce0a73d19e53a40c138edf 293 SUPERFAMILY SSF46785 1 83 4.44E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS41600 4134388ccee6014d8f2d6730af361cd8 309 Gene3D G3DSA:3.10.180.10 143 302 1.3E-30 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS41600 4134388ccee6014d8f2d6730af361cd8 309 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 144 254 8.5E-14 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMALA_RS41600 4134388ccee6014d8f2d6730af361cd8 309 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 12 123 2.5E-10 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMALA_RS41600 4134388ccee6014d8f2d6730af361cd8 309 Gene3D G3DSA:3.10.180.10 3 140 6.7E-24 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS41600 4134388ccee6014d8f2d6730af361cd8 309 SUPERFAMILY SSF54593 8 259 8.27E-43 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS00650 886854d227a3b0f0e70e6993af550bf7 296 Gene3D G3DSA:2.60.120.280 34 177 2.1E-11 T 29-03-2018 SMALA_RS00650 886854d227a3b0f0e70e6993af550bf7 296 SMART SM00342 205 288 8.7E-22 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS00650 886854d227a3b0f0e70e6993af550bf7 296 Gene3D G3DSA:1.10.10.60 243 296 3.7E-9 T 29-03-2018 SMALA_RS00650 886854d227a3b0f0e70e6993af550bf7 296 Gene3D G3DSA:1.10.10.60 184 241 5.6E-7 T 29-03-2018 SMALA_RS00650 886854d227a3b0f0e70e6993af550bf7 296 Pfam PF02311 AraC-like ligand binding domain 36 159 2.9E-8 T 29-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 SMALA_RS00650 886854d227a3b0f0e70e6993af550bf7 296 Pfam PF12833 Helix-turn-helix domain 211 290 2.3E-19 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS00650 886854d227a3b0f0e70e6993af550bf7 296 SUPERFAMILY SSF46689 244 290 2.87E-9 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS00650 886854d227a3b0f0e70e6993af550bf7 296 SUPERFAMILY SSF51215 44 92 5.62E-7 T 29-03-2018 SMALA_RS22665 149ef9620cb0e7d5bfe3a9f63fabb443 126 Gene3D G3DSA:4.10.910.10 87 122 3.5E-24 T 29-03-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMALA_RS22665 149ef9620cb0e7d5bfe3a9f63fabb443 126 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 120 27.105 T 29-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMALA_RS22665 149ef9620cb0e7d5bfe3a9f63fabb443 126 ProSitePatterns PS00646 Ribosomal protein S13 signature. 88 101 - T 29-03-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMALA_RS22665 149ef9620cb0e7d5bfe3a9f63fabb443 126 Gene3D G3DSA:1.10.8.50 1 67 1.8E-22 T 29-03-2018 SMALA_RS22665 149ef9620cb0e7d5bfe3a9f63fabb443 126 Gene3D G3DSA:4.10.910.10 68 86 3.5E-15 T 29-03-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMALA_RS22665 149ef9620cb0e7d5bfe3a9f63fabb443 126 SUPERFAMILY SSF46946 2 122 1.96E-43 T 29-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 SMALA_RS22665 149ef9620cb0e7d5bfe3a9f63fabb443 126 Pfam PF00416 Ribosomal protein S13/S18 3 109 3.6E-30 T 29-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMALA_RS22665 149ef9620cb0e7d5bfe3a9f63fabb443 126 PIRSF PIRSF002134 1 125 2.5E-41 T 29-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMALA_RS22665 149ef9620cb0e7d5bfe3a9f63fabb443 126 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 115 1.9E-50 T 29-03-2018 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS24395 64134435faab567e6479d17a291247b8 165 SUPERFAMILY SSF46557 8 82 3.66E-23 T 29-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 SMALA_RS24395 64134435faab567e6479d17a291247b8 165 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 86 161 1.3E-12 T 29-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 SMALA_RS24395 64134435faab567e6479d17a291247b8 165 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 22 53 - T 29-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 SMALA_RS24395 64134435faab567e6479d17a291247b8 165 Pfam PF03449 Transcription elongation factor, N-terminal 10 79 6.7E-25 T 29-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 SMALA_RS24395 64134435faab567e6479d17a291247b8 165 SUPERFAMILY SSF54534 84 160 5.89E-11 T 29-03-2018 SMALA_RS24395 64134435faab567e6479d17a291247b8 165 PIRSF PIRSF006092 3 164 2.5E-32 T 29-03-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 SMALA_RS24395 64134435faab567e6479d17a291247b8 165 Hamap MF_00105 Transcription elongation factor GreA [greA]. 7 161 27.465 T 29-03-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 SMALA_RS24395 64134435faab567e6479d17a291247b8 165 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 10 160 8.0E-43 T 29-03-2018 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 SMALA_RS24395 64134435faab567e6479d17a291247b8 165 Gene3D G3DSA:1.10.287.180 8 79 2.1E-25 T 29-03-2018 SMALA_RS24395 64134435faab567e6479d17a291247b8 165 Gene3D G3DSA:3.10.50.30 80 164 1.1E-15 T 29-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 SMALA_RS27320 f883c4ca0b16c78c30f33e1c74ea0a95 664 Pfam PF11896 Domain of unknown function (DUF3416) 3 190 1.8E-60 T 29-03-2018 IPR021828 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase, domain N/S GO:0004553 KEGG: 00500+2.4.99.16 SMALA_RS27320 f883c4ca0b16c78c30f33e1c74ea0a95 664 Gene3D G3DSA:2.60.40.1180 563 663 2.4E-42 T 29-03-2018 SMALA_RS27320 f883c4ca0b16c78c30f33e1c74ea0a95 664 Gene3D G3DSA:1.20.58.280 102 171 2.0E-25 T 29-03-2018 SMALA_RS27320 f883c4ca0b16c78c30f33e1c74ea0a95 664 Hamap MF_02124 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase [glgE]. 1 654 45.924 T 29-03-2018 IPR026585 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase GO:0016757 KEGG: 00500+2.4.99.16 SMALA_RS27320 f883c4ca0b16c78c30f33e1c74ea0a95 664 SUPERFAMILY SSF51445 196 559 4.01E-81 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS27320 f883c4ca0b16c78c30f33e1c74ea0a95 664 SMART SM00642 196 554 9.1E-4 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SMALA_RS27320 f883c4ca0b16c78c30f33e1c74ea0a95 664 SUPERFAMILY SSF51011 564 640 1.13E-5 T 29-03-2018 SMALA_RS27320 f883c4ca0b16c78c30f33e1c74ea0a95 664 Gene3D G3DSA:2.60.40.10 1 101 1.3E-43 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS27320 f883c4ca0b16c78c30f33e1c74ea0a95 664 Gene3D G3DSA:3.20.20.80 195 562 6.7E-64 T 29-03-2018 SMALA_RS15540 331abfe7faf4606a0b7102dbe819817a 448 Gene3D G3DSA:3.30.200.20 2 96 3.7E-17 T 29-03-2018 SMALA_RS15540 331abfe7faf4606a0b7102dbe819817a 448 SUPERFAMILY SSF56112 5 280 8.34E-64 T 29-03-2018 IPR011009 Protein kinase-like domain SMALA_RS15540 331abfe7faf4606a0b7102dbe819817a 448 Gene3D G3DSA:1.10.510.10 97 319 3.8E-44 T 29-03-2018 SMALA_RS15540 331abfe7faf4606a0b7102dbe819817a 448 SMART SM00220 9 286 5.5E-62 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMALA_RS15540 331abfe7faf4606a0b7102dbe819817a 448 Pfam PF00069 Protein kinase domain 9 278 3.8E-43 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMALA_RS15540 331abfe7faf4606a0b7102dbe819817a 448 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 126 138 - T 29-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMALA_RS15540 331abfe7faf4606a0b7102dbe819817a 448 PIRSF PIRSF000654 9 290 1.6E-28 T 29-03-2018 SMALA_RS22510 d26cbd63a23e0dd1fb2fe666a48323d9 706 Gene3D G3DSA:3.30.70.240 626 703 7.2E-32 T 29-03-2018 SMALA_RS22510 d26cbd63a23e0dd1fb2fe666a48323d9 706 Pfam PF03144 Elongation factor Tu domain 2 336 402 5.0E-14 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 SMALA_RS22510 d26cbd63a23e0dd1fb2fe666a48323d9 706 Gene3D G3DSA:3.30.70.870 412 504 1.4E-37 T 29-03-2018 SMALA_RS22510 d26cbd63a23e0dd1fb2fe666a48323d9 706 Pfam PF00679 Elongation factor G C-terminus 613 698 1.9E-30 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like SMALA_RS22510 d26cbd63a23e0dd1fb2fe666a48323d9 706 SUPERFAMILY SSF50447 276 416 2.1E-36 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain SMALA_RS22510 d26cbd63a23e0dd1fb2fe666a48323d9 706 Hamap MF_00054_B Elongation factor G [fusA]. 7 703 110.758 T 29-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SMALA_RS22510 d26cbd63a23e0dd1fb2fe666a48323d9 706 Pfam PF03764 Elongation factor G, domain IV 491 610 1.5E-49 T 29-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 SMALA_RS22510 d26cbd63a23e0dd1fb2fe666a48323d9 706 PRINTS PR00315 GTP-binding elongation factor signature 99 110 4.1E-16 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMALA_RS22510 d26cbd63a23e0dd1fb2fe666a48323d9 706 PRINTS PR00315 GTP-binding elongation factor signature 135 144 4.1E-16 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMALA_RS22510 d26cbd63a23e0dd1fb2fe666a48323d9 706 PRINTS PR00315 GTP-binding elongation factor signature 13 26 4.1E-16 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMALA_RS22510 d26cbd63a23e0dd1fb2fe666a48323d9 706 PRINTS PR00315 GTP-binding elongation factor signature 59 67 4.1E-16 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMALA_RS22510 d26cbd63a23e0dd1fb2fe666a48323d9 706 PRINTS PR00315 GTP-binding elongation factor signature 83 93 4.1E-16 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMALA_RS22510 d26cbd63a23e0dd1fb2fe666a48323d9 706 SUPERFAMILY SSF52540 7 293 3.46E-104 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS22510 d26cbd63a23e0dd1fb2fe666a48323d9 706 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 52 67 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site SMALA_RS22510 d26cbd63a23e0dd1fb2fe666a48323d9 706 Gene3D G3DSA:3.30.230.10 505 625 8.9E-47 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SMALA_RS22510 d26cbd63a23e0dd1fb2fe666a48323d9 706 SUPERFAMILY SSF54211 491 611 1.26E-42 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SMALA_RS22510 d26cbd63a23e0dd1fb2fe666a48323d9 706 SMART SM00838 612 699 2.3E-58 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like SMALA_RS22510 d26cbd63a23e0dd1fb2fe666a48323d9 706 Gene3D G3DSA:2.40.30.10 299 411 7.0E-32 T 29-03-2018 SMALA_RS22510 d26cbd63a23e0dd1fb2fe666a48323d9 706 Gene3D G3DSA:3.40.50.300 7 298 2.8E-57 T 29-03-2018 SMALA_RS22510 d26cbd63a23e0dd1fb2fe666a48323d9 706 SUPERFAMILY SSF54980 416 493 2.48E-25 T 29-03-2018 IPR035647 EF-G domain III/V-like SMALA_RS22510 d26cbd63a23e0dd1fb2fe666a48323d9 706 SMART SM00889 492 610 2.1E-74 T 29-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 SMALA_RS22510 d26cbd63a23e0dd1fb2fe666a48323d9 706 Pfam PF14492 Elongation Factor G, domain II 416 490 1.4E-34 T 29-03-2018 SMALA_RS22510 d26cbd63a23e0dd1fb2fe666a48323d9 706 TIGRFAM TIGR00484 EF-G: translation elongation factor G 5 704 0.0 T 29-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SMALA_RS22510 d26cbd63a23e0dd1fb2fe666a48323d9 706 SUPERFAMILY SSF54980 615 702 1.01E-30 T 29-03-2018 IPR035647 EF-G domain III/V-like SMALA_RS22510 d26cbd63a23e0dd1fb2fe666a48323d9 706 Pfam PF00009 Elongation factor Tu GTP binding domain 10 293 1.0E-65 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMALA_RS22510 d26cbd63a23e0dd1fb2fe666a48323d9 706 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 11 185 7.0E-34 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 SMALA_RS27160 9d62f5b7742ef5d53c72c852a64ef947 475 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 2 469 4.9E-165 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMALA_RS27160 9d62f5b7742ef5d53c72c852a64ef947 475 ProSitePatterns PS00110 Pyruvate kinase active site signature. 212 224 - T 29-03-2018 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMALA_RS27160 9d62f5b7742ef5d53c72c852a64ef947 475 SUPERFAMILY SSF52935 320 470 1.31E-37 T 29-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMALA_RS27160 9d62f5b7742ef5d53c72c852a64ef947 475 Pfam PF02887 Pyruvate kinase, alpha/beta domain 356 468 3.9E-27 T 29-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMALA_RS27160 9d62f5b7742ef5d53c72c852a64ef947 475 Gene3D G3DSA:3.40.1380.20 319 471 4.1E-45 T 29-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMALA_RS27160 9d62f5b7742ef5d53c72c852a64ef947 475 Pfam PF00224 Pyruvate kinase, barrel domain 1 338 6.3E-128 T 29-03-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMALA_RS27160 9d62f5b7742ef5d53c72c852a64ef947 475 Gene3D G3DSA:3.20.20.60 159 318 8.4E-63 T 29-03-2018 SMALA_RS27160 9d62f5b7742ef5d53c72c852a64ef947 475 SUPERFAMILY SSF51621 1 74 1.36E-98 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SMALA_RS27160 9d62f5b7742ef5d53c72c852a64ef947 475 SUPERFAMILY SSF51621 154 336 1.36E-98 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SMALA_RS27160 9d62f5b7742ef5d53c72c852a64ef947 475 Gene3D G3DSA:3.20.20.60 1 80 1.1E-16 T 29-03-2018 SMALA_RS27160 9d62f5b7742ef5d53c72c852a64ef947 475 PRINTS PR01050 Pyruvate kinase family signature 241 265 1.7E-62 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMALA_RS27160 9d62f5b7742ef5d53c72c852a64ef947 475 PRINTS PR01050 Pyruvate kinase family signature 310 326 1.7E-62 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMALA_RS27160 9d62f5b7742ef5d53c72c852a64ef947 475 PRINTS PR01050 Pyruvate kinase family signature 291 309 1.7E-62 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMALA_RS27160 9d62f5b7742ef5d53c72c852a64ef947 475 PRINTS PR01050 Pyruvate kinase family signature 184 198 1.7E-62 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMALA_RS27160 9d62f5b7742ef5d53c72c852a64ef947 475 PRINTS PR01050 Pyruvate kinase family signature 266 290 1.7E-62 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMALA_RS27160 9d62f5b7742ef5d53c72c852a64ef947 475 PRINTS PR01050 Pyruvate kinase family signature 214 240 1.7E-62 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMALA_RS27160 9d62f5b7742ef5d53c72c852a64ef947 475 PRINTS PR01050 Pyruvate kinase family signature 59 75 1.7E-62 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMALA_RS27160 9d62f5b7742ef5d53c72c852a64ef947 475 SUPERFAMILY SSF50800 71 164 6.28E-27 T 29-03-2018 IPR011037 Pyruvate kinase-like, insert domain SMALA_RS27160 9d62f5b7742ef5d53c72c852a64ef947 475 Gene3D G3DSA:2.40.33.10 81 158 1.8E-27 T 29-03-2018 SMALA_RS00040 72d774dfa477e95fc064c965e4552a8e 94 Gene3D G3DSA:1.10.260.40 3 76 4.3E-8 T 29-03-2018 SMALA_RS00040 72d774dfa477e95fc064c965e4552a8e 94 SUPERFAMILY SSF47413 7 68 2.46E-7 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS00040 72d774dfa477e95fc064c965e4552a8e 94 Pfam PF08667 BetR domain 23 77 1.5E-5 T 29-03-2018 IPR013975 Transcription regulator BetR, N-terminal SMALA_RS04285 fbefe057b322b9a65aba13efe805d987 503 SMART SM00382 7 193 3.2E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS04285 fbefe057b322b9a65aba13efe805d987 503 SMART SM00382 272 464 1.2E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS04285 fbefe057b322b9a65aba13efe805d987 503 ProSitePatterns PS00211 ABC transporters family signature. 117 131 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS04285 fbefe057b322b9a65aba13efe805d987 503 Gene3D G3DSA:3.40.50.300 244 499 5.1E-61 T 29-03-2018 SMALA_RS04285 fbefe057b322b9a65aba13efe805d987 503 Gene3D G3DSA:3.40.50.300 1 240 5.8E-51 T 29-03-2018 SMALA_RS04285 fbefe057b322b9a65aba13efe805d987 503 Pfam PF00005 ABC transporter 264 415 1.3E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS04285 fbefe057b322b9a65aba13efe805d987 503 Pfam PF00005 ABC transporter 1 144 5.5E-20 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS04285 fbefe057b322b9a65aba13efe805d987 503 SUPERFAMILY SSF52540 2 221 2.21E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS04285 fbefe057b322b9a65aba13efe805d987 503 ProSitePatterns PS00211 ABC transporters family signature. 387 401 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS04285 fbefe057b322b9a65aba13efe805d987 503 SUPERFAMILY SSF52540 246 489 2.09E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS09645 cb305a66932ab72bc0ad730dcaadf90f 334 Pfam PF03741 Integral membrane protein TerC family 69 275 1.4E-53 T 29-03-2018 IPR005496 Integral membrane protein TerC GO:0016021 SMALA_RS09645 cb305a66932ab72bc0ad730dcaadf90f 334 TIGRFAM TIGR03718 R_switched_Alx: integral membrane protein, TerC family 4 312 1.8E-116 T 29-03-2018 IPR022369 Integral membrane protein TerC, riboswitch-linked GO:0016021 SMALA_RS33830 7bfe24835b2d8f8fd97752d19d841da3 386 ProDom PD042532 ISOMERASE L-RHAMNOSE METAL-BINDING METABOLISM RHAMNOSE MANGANESE ENZYME KINASE 3D-STRUCTURE RHAA/RHAB 105 276 1.0E-6 T 29-03-2018 SMALA_RS33830 7bfe24835b2d8f8fd97752d19d841da3 386 Gene3D G3DSA:3.20.20.150 1 377 7.6E-109 T 29-03-2018 SMALA_RS33830 7bfe24835b2d8f8fd97752d19d841da3 386 Pfam PF01261 Xylose isomerase-like TIM barrel 55 218 9.3E-7 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SMALA_RS33830 7bfe24835b2d8f8fd97752d19d841da3 386 SUPERFAMILY SSF51658 25 358 6.5E-97 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SMALA_RS33830 7bfe24835b2d8f8fd97752d19d841da3 386 TIGRFAM TIGR02635 RhaI_grampos: L-rhamnose isomerase 6 376 8.0E-201 T 29-03-2018 IPR013457 Rhamnose isomerase-related SMALA_RS39270 a6c23c9f823161913a13a116dd1dd23f 310 Gene3D G3DSA:3.30.230.10 37 268 2.3E-9 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SMALA_RS39270 a6c23c9f823161913a13a116dd1dd23f 310 Pfam PF00288 GHMP kinases N terminal domain 91 124 2.5E-6 T 29-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 SMALA_RS39270 a6c23c9f823161913a13a116dd1dd23f 310 PIRSF PIRSF033887 5 297 3.2E-81 T 29-03-2018 IPR012363 Propanediol utilisation/coumermycin biosynthesis, PduX-related KEGG: 00040+2.7.1.17|KEGG: 00860+2.7.1.177|MetaCyc: PWY-5443 SMALA_RS39270 a6c23c9f823161913a13a116dd1dd23f 310 SUPERFAMILY SSF54211 18 172 3.49E-13 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SMALA_RS16985 674d11b48faa7c5d2652aa52654bfc41 256 SUPERFAMILY SSF46894 186 255 3.37E-23 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS16985 674d11b48faa7c5d2652aa52654bfc41 256 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 226 238 1.3E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS16985 674d11b48faa7c5d2652aa52654bfc41 256 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 196 210 1.3E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS16985 674d11b48faa7c5d2652aa52654bfc41 256 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 210 226 1.3E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS16985 674d11b48faa7c5d2652aa52654bfc41 256 Gene3D G3DSA:3.40.50.2300 39 170 2.5E-23 T 29-03-2018 SMALA_RS16985 674d11b48faa7c5d2652aa52654bfc41 256 SMART SM00421 193 250 3.1E-25 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS16985 674d11b48faa7c5d2652aa52654bfc41 256 ProSitePatterns PS00622 LuxR-type HTH domain signature. 210 237 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS16985 674d11b48faa7c5d2652aa52654bfc41 256 Pfam PF00196 Bacterial regulatory proteins, luxR family 195 250 1.0E-20 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS16985 674d11b48faa7c5d2652aa52654bfc41 256 Gene3D G3DSA:1.10.10.10 171 256 2.3E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS16985 674d11b48faa7c5d2652aa52654bfc41 256 SUPERFAMILY SSF52172 39 177 5.69E-22 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS16985 674d11b48faa7c5d2652aa52654bfc41 256 Pfam PF00072 Response regulator receiver domain 42 159 4.8E-16 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS16985 674d11b48faa7c5d2652aa52654bfc41 256 SMART SM00448 40 159 2.1E-15 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS26565 fa5de641a2f506c9809b9769894195a9 386 SMART SM00387 254 378 1.2E-33 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS26565 fa5de641a2f506c9809b9769894195a9 386 SMART SM00304 81 134 3.5E-12 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMALA_RS26565 fa5de641a2f506c9809b9769894195a9 386 SUPERFAMILY SSF47384 118 199 5.3E-18 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS26565 fa5de641a2f506c9809b9769894195a9 386 SMART SM00388 135 199 1.2E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS26565 fa5de641a2f506c9809b9769894195a9 386 PRINTS PR00344 Bacterial sensor protein C-terminal signature 339 357 1.8E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS26565 fa5de641a2f506c9809b9769894195a9 386 PRINTS PR00344 Bacterial sensor protein C-terminal signature 362 375 1.8E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS26565 fa5de641a2f506c9809b9769894195a9 386 PRINTS PR00344 Bacterial sensor protein C-terminal signature 293 307 1.8E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS26565 fa5de641a2f506c9809b9769894195a9 386 SUPERFAMILY SSF55874 188 376 3.01E-35 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS26565 fa5de641a2f506c9809b9769894195a9 386 Gene3D G3DSA:1.10.287.130 125 195 2.3E-16 T 29-03-2018 SMALA_RS26565 fa5de641a2f506c9809b9769894195a9 386 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 255 375 2.3E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS26565 fa5de641a2f506c9809b9769894195a9 386 Pfam PF00512 His Kinase A (phospho-acceptor) domain 136 199 4.8E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS26565 fa5de641a2f506c9809b9769894195a9 386 Gene3D G3DSA:3.30.565.10 225 385 3.0E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS26565 fa5de641a2f506c9809b9769894195a9 386 Pfam PF00672 HAMP domain 83 130 2.5E-11 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMALA_RS26565 fa5de641a2f506c9809b9769894195a9 386 SUPERFAMILY SSF158472 83 130 3.01E-11 T 29-03-2018 SMALA_RS04645 4540559de6b2ab81a244ec5d2e822355 308 SUPERFAMILY SSF52540 2 226 5.06E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS04645 4540559de6b2ab81a244ec5d2e822355 308 Gene3D G3DSA:3.40.50.300 1 286 1.1E-60 T 29-03-2018 SMALA_RS04645 4540559de6b2ab81a244ec5d2e822355 308 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS04645 4540559de6b2ab81a244ec5d2e822355 308 SMART SM00382 29 224 1.2E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS04645 4540559de6b2ab81a244ec5d2e822355 308 Pfam PF00005 ABC transporter 21 158 8.2E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS14175 32088c91212a551e61b30c16c8ea7707 298 SUPERFAMILY SSF54637 117 294 1.26E-46 T 29-03-2018 IPR029069 HotDog domain SMALA_RS14175 32088c91212a551e61b30c16c8ea7707 298 SUPERFAMILY SSF54637 6 115 4.98E-41 T 29-03-2018 IPR029069 HotDog domain SMALA_RS14175 32088c91212a551e61b30c16c8ea7707 298 Pfam PF13622 Thioesterase-like superfamily 34 290 3.0E-59 T 29-03-2018 SMALA_RS14175 32088c91212a551e61b30c16c8ea7707 298 Gene3D G3DSA:3.10.129.10 142 294 4.1E-49 T 29-03-2018 SMALA_RS14175 32088c91212a551e61b30c16c8ea7707 298 Gene3D G3DSA:3.10.129.10 2 117 5.4E-45 T 29-03-2018 SMALA_RS36765 75393b57577b73b405ce7cc631b21d5f 2207 Gene3D G3DSA:3.40.366.10 575 716 8.0E-42 T 29-03-2018 SMALA_RS36765 75393b57577b73b405ce7cc631b21d5f 2207 SUPERFAMILY SSF47336 2041 2122 1.83E-22 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS36765 75393b57577b73b405ce7cc631b21d5f 2207 SMART SM01294 2048 2115 7.2E-5 T 29-03-2018 SMALA_RS36765 75393b57577b73b405ce7cc631b21d5f 2207 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 292 409 1.2E-41 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS36765 75393b57577b73b405ce7cc631b21d5f 2207 SUPERFAMILY SSF51735 1234 1424 2.72E-32 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS36765 75393b57577b73b405ce7cc631b21d5f 2207 SUPERFAMILY SSF55048 702 770 5.36E-11 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS36765 75393b57577b73b405ce7cc631b21d5f 2207 Gene3D G3DSA:3.90.180.10 1426 1753 1.1E-55 T 29-03-2018 SMALA_RS36765 75393b57577b73b405ce7cc631b21d5f 2207 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 579 879 4.3E-117 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS36765 75393b57577b73b405ce7cc631b21d5f 2207 SUPERFAMILY SSF51735 1546 1722 6.66E-33 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS36765 75393b57577b73b405ce7cc631b21d5f 2207 Gene3D G3DSA:3.30.70.250 717 761 5.1E-15 T 29-03-2018 SMALA_RS36765 75393b57577b73b405ce7cc631b21d5f 2207 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 412 537 2.5E-13 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS36765 75393b57577b73b405ce7cc631b21d5f 2207 Pfam PF08659 KR domain 1761 1940 2.7E-57 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS36765 75393b57577b73b405ce7cc631b21d5f 2207 Gene3D G3DSA:3.40.366.10 762 886 3.4E-28 T 29-03-2018 SMALA_RS36765 75393b57577b73b405ce7cc631b21d5f 2207 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2074 2089 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS36765 75393b57577b73b405ce7cc631b21d5f 2207 SMART SM00826 948 1112 2.0E-84 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS36765 75393b57577b73b405ce7cc631b21d5f 2207 Gene3D G3DSA:3.40.47.10 299 460 9.4E-60 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS36765 75393b57577b73b405ce7cc631b21d5f 2207 SMART SM00829 1448 1751 3.0E-167 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS36765 75393b57577b73b405ce7cc631b21d5f 2207 Gene3D G3DSA:1.10.1200.10 2026 2125 2.4E-22 T 29-03-2018 SMALA_RS36765 75393b57577b73b405ce7cc631b21d5f 2207 Gene3D G3DSA:3.40.47.10 26 296 1.2E-86 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS36765 75393b57577b73b405ce7cc631b21d5f 2207 Gene3D G3DSA:3.40.50.720 1754 2014 4.6E-48 T 29-03-2018 SMALA_RS36765 75393b57577b73b405ce7cc631b21d5f 2207 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 1468 1523 1.3E-5 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS36765 75393b57577b73b405ce7cc631b21d5f 2207 Pfam PF08990 Erythronolide synthase docking 2 27 4.7E-13 T 29-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 SMALA_RS36765 75393b57577b73b405ce7cc631b21d5f 2207 SUPERFAMILY SSF51735 1758 2012 4.86E-46 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS36765 75393b57577b73b405ce7cc631b21d5f 2207 SUPERFAMILY SSF50129 1445 1575 1.98E-24 T 29-03-2018 IPR011032 GroES-like SMALA_RS36765 75393b57577b73b405ce7cc631b21d5f 2207 SMART SM00823 Phosphopantetheine attachment site 2047 2119 1.5E-30 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS36765 75393b57577b73b405ce7cc631b21d5f 2207 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 284 8.7E-92 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS36765 75393b57577b73b405ce7cc631b21d5f 2207 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1761 1941 1.0E-57 T 29-03-2018 SMALA_RS36765 75393b57577b73b405ce7cc631b21d5f 2207 Pfam PF00698 Acyl transferase domain 578 898 1.4E-84 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS36765 75393b57577b73b405ce7cc631b21d5f 2207 SMART SM00825 Beta-ketoacyl synthase 36 462 1.0E-209 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS36765 75393b57577b73b405ce7cc631b21d5f 2207 Pfam PF00550 Phosphopantetheine attachment site 2050 2115 1.0E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS36765 75393b57577b73b405ce7cc631b21d5f 2207 SUPERFAMILY SSF52151 577 704 3.66E-66 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS36765 75393b57577b73b405ce7cc631b21d5f 2207 SUPERFAMILY SSF52151 771 870 3.66E-66 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS36765 75393b57577b73b405ce7cc631b21d5f 2207 SUPERFAMILY SSF53901 31 399 7.79E-100 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS36765 75393b57577b73b405ce7cc631b21d5f 2207 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 197 213 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS36765 75393b57577b73b405ce7cc631b21d5f 2207 Pfam PF13602 Zinc-binding dehydrogenase 1622 1751 8.0E-17 T 29-03-2018 SMALA_RS36765 75393b57577b73b405ce7cc631b21d5f 2207 Pfam PF14765 Polyketide synthase dehydratase 948 1226 5.0E-57 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS40250 176bf5d4df2364bbed79c11d7fab998b 372 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 20 142 9.5E-13 T 29-03-2018 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 SMALA_RS40250 176bf5d4df2364bbed79c11d7fab998b 372 SUPERFAMILY SSF51735 20 149 1.69E-10 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS40250 176bf5d4df2364bbed79c11d7fab998b 372 Gene3D G3DSA:3.40.50.720 6 174 5.6E-12 T 29-03-2018 SMALA_RS17640 93bb6128c754f65f6f83825f9818ad1e 378 Pfam PF03459 TOBE domain 307 367 4.9E-8 T 29-03-2018 IPR005116 Transport-associated OB, type 1 SMALA_RS17640 93bb6128c754f65f6f83825f9818ad1e 378 Pfam PF00005 ABC transporter 22 163 2.3E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS17640 93bb6128c754f65f6f83825f9818ad1e 378 Gene3D G3DSA:2.40.50.100 248 284 4.7E-17 T 29-03-2018 SMALA_RS17640 93bb6128c754f65f6f83825f9818ad1e 378 Gene3D G3DSA:3.40.50.300 1 247 9.7E-66 T 29-03-2018 SMALA_RS17640 93bb6128c754f65f6f83825f9818ad1e 378 Gene3D G3DSA:2.40.50.140 285 359 8.5E-14 T 29-03-2018 SMALA_RS17640 93bb6128c754f65f6f83825f9818ad1e 378 SUPERFAMILY SSF50331 238 376 5.95E-20 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal SMALA_RS17640 93bb6128c754f65f6f83825f9818ad1e 378 SUPERFAMILY SSF52540 7 245 6.39E-83 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS17640 93bb6128c754f65f6f83825f9818ad1e 378 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS17640 93bb6128c754f65f6f83825f9818ad1e 378 SMART SM00382 30 213 1.3E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS36740 bbb0bc7f09b39396004261ca72b86862 1299 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 293 409 8.6E-42 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS36740 bbb0bc7f09b39396004261ca72b86862 1299 SUPERFAMILY SSF52151 572 670 3.92E-21 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS36740 bbb0bc7f09b39396004261ca72b86862 1299 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1048 1222 3.0E-10 T 29-03-2018 SMALA_RS36740 bbb0bc7f09b39396004261ca72b86862 1299 Gene3D G3DSA:3.40.47.10 26 296 6.2E-78 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS36740 bbb0bc7f09b39396004261ca72b86862 1299 Pfam PF00698 Acyl transferase domain 619 669 2.5E-9 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS36740 bbb0bc7f09b39396004261ca72b86862 1299 Pfam PF08990 Erythronolide synthase docking 2 27 4.6E-12 T 29-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 SMALA_RS36740 bbb0bc7f09b39396004261ca72b86862 1299 Gene3D G3DSA:3.40.47.10 297 460 9.0E-56 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS36740 bbb0bc7f09b39396004261ca72b86862 1299 SUPERFAMILY SSF51735 826 1033 9.84E-40 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS36740 bbb0bc7f09b39396004261ca72b86862 1299 SMART SM00825 Beta-ketoacyl synthase 36 462 1.9E-194 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS36740 bbb0bc7f09b39396004261ca72b86862 1299 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 284 1.0E-81 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS36740 bbb0bc7f09b39396004261ca72b86862 1299 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 413 530 2.7E-12 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS36740 bbb0bc7f09b39396004261ca72b86862 1299 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 574 827 1.7E-7 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS36740 bbb0bc7f09b39396004261ca72b86862 1299 SUPERFAMILY SSF53901 32 399 1.92E-96 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS36740 bbb0bc7f09b39396004261ca72b86862 1299 Pfam PF08659 KR domain 1048 1220 9.9E-27 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS36740 bbb0bc7f09b39396004261ca72b86862 1299 Gene3D G3DSA:3.40.366.10 557 1063 7.2E-42 T 29-03-2018 SMALA_RS36740 bbb0bc7f09b39396004261ca72b86862 1299 SUPERFAMILY SSF51735 1048 1277 1.65E-28 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS36740 bbb0bc7f09b39396004261ca72b86862 1299 Gene3D G3DSA:3.40.50.720 1064 1292 2.0E-25 T 29-03-2018 SMALA_RS38395 6337c4b809752a6afa93fe9a52fa968f 247 Gene3D G3DSA:3.40.50.1000 108 247 2.2E-21 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS38395 6337c4b809752a6afa93fe9a52fa968f 247 Pfam PF13419 Haloacid dehalogenase-like hydrolase 13 209 2.3E-12 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS38395 6337c4b809752a6afa93fe9a52fa968f 247 Gene3D G3DSA:1.10.150.240 24 107 7.2E-25 T 29-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 SMALA_RS38395 6337c4b809752a6afa93fe9a52fa968f 247 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 128 141 3.1E-6 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMALA_RS38395 6337c4b809752a6afa93fe9a52fa968f 247 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 161 177 3.1E-6 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMALA_RS38395 6337c4b809752a6afa93fe9a52fa968f 247 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 10 21 3.1E-6 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMALA_RS38395 6337c4b809752a6afa93fe9a52fa968f 247 TIGRFAM TIGR02009 PGMB-YQAB-SF: beta-phosphoglucomutase family hydrolase 10 215 2.4E-47 T 29-03-2018 IPR010976 Beta-phosphoglucomutase hydrolase SMALA_RS38395 6337c4b809752a6afa93fe9a52fa968f 247 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 106 216 2.5E-11 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMALA_RS38395 6337c4b809752a6afa93fe9a52fa968f 247 SUPERFAMILY SSF56784 10 244 1.5E-36 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS40915 1aec598c9589e74c6392ff36cd887f5d 3069 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2529 2544 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS40915 1aec598c9589e74c6392ff36cd887f5d 3069 SUPERFAMILY SSF47336 2498 2567 8.9E-18 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS40915 1aec598c9589e74c6392ff36cd887f5d 3069 Gene3D G3DSA:1.10.1200.10 2511 2565 1.6E-22 T 29-03-2018 SMALA_RS40915 1aec598c9589e74c6392ff36cd887f5d 3069 SUPERFAMILY SSF56801 437 996 1.31E-159 T 29-03-2018 SMALA_RS40915 1aec598c9589e74c6392ff36cd887f5d 3069 Gene3D G3DSA:1.10.1200.10 986 1050 9.7E-24 T 29-03-2018 SMALA_RS40915 1aec598c9589e74c6392ff36cd887f5d 3069 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 2898 3055 1.0E-43 T 29-03-2018 IPR010060 Non-ribosomal peptide synthase SMALA_RS40915 1aec598c9589e74c6392ff36cd887f5d 3069 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 1375 1528 3.8E-42 T 29-03-2018 IPR010060 Non-ribosomal peptide synthase SMALA_RS40915 1aec598c9589e74c6392ff36cd887f5d 3069 Gene3D G3DSA:3.40.50.980 2174 2299 1.0E-36 T 29-03-2018 SMALA_RS40915 1aec598c9589e74c6392ff36cd887f5d 3069 Gene3D G3DSA:3.40.50.980 629 784 2.8E-29 T 29-03-2018 SMALA_RS40915 1aec598c9589e74c6392ff36cd887f5d 3069 SUPERFAMILY SSF47336 976 1045 1.09E-17 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS40915 1aec598c9589e74c6392ff36cd887f5d 3069 SUPERFAMILY SSF52777 191 464 1.08E-36 T 29-03-2018 SMALA_RS40915 1aec598c9589e74c6392ff36cd887f5d 3069 SUPERFAMILY SSF52777 1059 1251 2.89E-28 T 29-03-2018 SMALA_RS40915 1aec598c9589e74c6392ff36cd887f5d 3069 SUPERFAMILY SSF52777 2582 2774 2.67E-28 T 29-03-2018 SMALA_RS40915 1aec598c9589e74c6392ff36cd887f5d 3069 Pfam PF13193 AMP-binding enzyme C-terminal domain 885 958 1.0E-15 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS40915 1aec598c9589e74c6392ff36cd887f5d 3069 Pfam PF13193 AMP-binding enzyme C-terminal domain 2407 2480 7.3E-15 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS40915 1aec598c9589e74c6392ff36cd887f5d 3069 SUPERFAMILY SSF52777 11 185 4.89E-38 T 29-03-2018 SMALA_RS40915 1aec598c9589e74c6392ff36cd887f5d 3069 Gene3D G3DSA:3.30.300.30 2394 2510 5.7E-40 T 29-03-2018 SMALA_RS40915 1aec598c9589e74c6392ff36cd887f5d 3069 Gene3D G3DSA:3.30.300.30 872 985 3.1E-41 T 29-03-2018 SMALA_RS40915 1aec598c9589e74c6392ff36cd887f5d 3069 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2143 2154 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS40915 1aec598c9589e74c6392ff36cd887f5d 3069 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1007 1022 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS40915 1aec598c9589e74c6392ff36cd887f5d 3069 SUPERFAMILY SSF52777 2763 3031 3.34E-31 T 29-03-2018 SMALA_RS40915 1aec598c9589e74c6392ff36cd887f5d 3069 Gene3D G3DSA:2.30.38.10 787 870 2.9E-26 T 29-03-2018 SMALA_RS40915 1aec598c9589e74c6392ff36cd887f5d 3069 Gene3D G3DSA:2.30.38.10 2300 2391 9.6E-25 T 29-03-2018 SMALA_RS40915 1aec598c9589e74c6392ff36cd887f5d 3069 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 498 901 7.7E-135 T 29-03-2018 IPR010071 Amino acid adenylation domain SMALA_RS40915 1aec598c9589e74c6392ff36cd887f5d 3069 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2014 2423 1.0E-138 T 29-03-2018 IPR010071 Amino acid adenylation domain SMALA_RS40915 1aec598c9589e74c6392ff36cd887f5d 3069 ProSitePatterns PS00455 Putative AMP-binding domain signature. 624 635 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS40915 1aec598c9589e74c6392ff36cd887f5d 3069 Gene3D G3DSA:3.30.559.10 2566 2775 1.1E-26 T 29-03-2018 SMALA_RS40915 1aec598c9589e74c6392ff36cd887f5d 3069 Gene3D G3DSA:3.30.559.10 1051 1277 2.0E-26 T 29-03-2018 SMALA_RS40915 1aec598c9589e74c6392ff36cd887f5d 3069 Gene3D G3DSA:3.30.559.10 1519 1738 3.7E-42 T 29-03-2018 SMALA_RS40915 1aec598c9589e74c6392ff36cd887f5d 3069 Pfam PF00668 Condensation domain 1083 1507 3.2E-31 T 29-03-2018 IPR001242 Condensation domain SMALA_RS40915 1aec598c9589e74c6392ff36cd887f5d 3069 Pfam PF00668 Condensation domain 1536 1971 1.8E-88 T 29-03-2018 IPR001242 Condensation domain SMALA_RS40915 1aec598c9589e74c6392ff36cd887f5d 3069 Pfam PF00668 Condensation domain 9 458 9.2E-70 T 29-03-2018 IPR001242 Condensation domain SMALA_RS40915 1aec598c9589e74c6392ff36cd887f5d 3069 Pfam PF00668 Condensation domain 2606 2955 1.0E-28 T 29-03-2018 IPR001242 Condensation domain SMALA_RS40915 1aec598c9589e74c6392ff36cd887f5d 3069 SUPERFAMILY SSF52777 1718 1981 2.56E-58 T 29-03-2018 SMALA_RS40915 1aec598c9589e74c6392ff36cd887f5d 3069 Gene3D G3DSA:3.40.50.980 470 628 2.0E-49 T 29-03-2018 SMALA_RS40915 1aec598c9589e74c6392ff36cd887f5d 3069 Gene3D G3DSA:3.40.50.980 1986 2144 4.9E-47 T 29-03-2018 SMALA_RS40915 1aec598c9589e74c6392ff36cd887f5d 3069 SUPERFAMILY SSF52777 1534 1733 1.45E-43 T 29-03-2018 SMALA_RS40915 1aec598c9589e74c6392ff36cd887f5d 3069 Gene3D G3DSA:3.30.1110.20 2145 2173 2.9E-8 T 29-03-2018 SMALA_RS40915 1aec598c9589e74c6392ff36cd887f5d 3069 Gene3D G3DSA:3.30.559.10 4 199 5.8E-31 T 29-03-2018 SMALA_RS40915 1aec598c9589e74c6392ff36cd887f5d 3069 SUPERFAMILY SSF52777 1240 1504 2.22E-31 T 29-03-2018 SMALA_RS40915 1aec598c9589e74c6392ff36cd887f5d 3069 SUPERFAMILY SSF56801 1952 2518 2.62E-169 T 29-03-2018 SMALA_RS40915 1aec598c9589e74c6392ff36cd887f5d 3069 SMART SM00823 Phosphopantetheine attachment site 983 1051 4.3E-7 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS40915 1aec598c9589e74c6392ff36cd887f5d 3069 SMART SM00823 Phosphopantetheine attachment site 2505 2573 7.3E-9 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS40915 1aec598c9589e74c6392ff36cd887f5d 3069 Pfam PF00550 Phosphopantetheine attachment site 2506 2568 1.2E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS40915 1aec598c9589e74c6392ff36cd887f5d 3069 Pfam PF00550 Phosphopantetheine attachment site 984 1045 2.1E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS40915 1aec598c9589e74c6392ff36cd887f5d 3069 Pfam PF00501 AMP-binding enzyme 477 877 4.7E-99 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS40915 1aec598c9589e74c6392ff36cd887f5d 3069 Pfam PF00501 AMP-binding enzyme 1994 2399 6.2E-103 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS25785 8ea03b8d6f1bdecde7c2d48894b96fc7 286 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 16 31 - T 29-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMALA_RS25785 8ea03b8d6f1bdecde7c2d48894b96fc7 286 Gene3D G3DSA:3.20.20.20 2 286 4.9E-86 T 29-03-2018 SMALA_RS25785 8ea03b8d6f1bdecde7c2d48894b96fc7 286 Pfam PF00809 Pterin binding enzyme 17 257 8.7E-65 T 29-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMALA_RS25785 8ea03b8d6f1bdecde7c2d48894b96fc7 286 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 16 271 4.3E-81 T 29-03-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 SMALA_RS25785 8ea03b8d6f1bdecde7c2d48894b96fc7 286 SUPERFAMILY SSF51717 5 276 2.88E-81 T 29-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMALA_RS25785 8ea03b8d6f1bdecde7c2d48894b96fc7 286 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 50 63 - T 29-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 SUPERFAMILY SSF56801 2591 3151 1.57E-142 T 29-03-2018 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 Gene3D G3DSA:1.10.1200.10 6190 6246 4.9E-23 T 29-03-2018 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 Gene3D G3DSA:3.30.559.10 2 199 2.1E-23 T 29-03-2018 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 Gene3D G3DSA:3.30.559.10 2144 2334 2.3E-42 T 29-03-2018 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 Gene3D G3DSA:3.30.559.10 6895 7088 2.2E-41 T 29-03-2018 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 Gene3D G3DSA:2.30.38.10 4454 4535 1.2E-25 T 29-03-2018 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 Gene3D G3DSA:2.30.38.10 1881 1962 2.6E-22 T 29-03-2018 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 SUPERFAMILY SSF52777 14 192 1.22E-29 T 29-03-2018 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 SUPERFAMILY SSF52777 3869 4129 5.89E-46 T 29-03-2018 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1009 1024 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 Gene3D G3DSA:2.30.38.10 780 863 1.5E-22 T 29-03-2018 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 Gene3D G3DSA:2.30.38.10 2948 3030 8.0E-17 T 29-03-2018 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2095 2110 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 Gene3D G3DSA:3.40.50.980 7366 7523 8.5E-43 T 29-03-2018 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 Gene3D G3DSA:3.40.50.980 462 622 2.1E-39 T 29-03-2018 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 Gene3D G3DSA:3.40.50.980 4136 4293 3.1E-43 T 29-03-2018 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 Gene3D G3DSA:3.40.50.980 1553 1715 4.9E-38 T 29-03-2018 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 Gene3D G3DSA:3.40.50.980 5679 5840 5.9E-39 T 29-03-2018 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 SUPERFAMILY SSF52777 4926 5180 3.56E-20 T 29-03-2018 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 SUPERFAMILY SSF56801 1555 2083 3.4E-126 T 29-03-2018 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 Gene3D G3DSA:3.30.300.30 1963 2057 5.3E-29 T 29-03-2018 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 SUPERFAMILY SSF52777 4729 4934 7.56E-28 T 29-03-2018 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 SUPERFAMILY SSF47336 6178 6246 2.62E-18 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 SUPERFAMILY SSF52777 3405 3656 8.12E-26 T 29-03-2018 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 Gene3D G3DSA:3.40.50.980 2625 2787 2.6E-46 T 29-03-2018 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 5053 5177 1.8E-22 T 29-03-2018 IPR010060 Non-ribosomal peptide synthase SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 8275 8430 2.2E-31 T 29-03-2018 IPR010060 Non-ribosomal peptide synthase SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 3529 3676 4.9E-28 T 29-03-2018 IPR010060 Non-ribosomal peptide synthase SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 SUPERFAMILY SSF52777 6270 6442 2.78E-48 T 29-03-2018 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 SUPERFAMILY SSF52777 8147 8409 2.33E-26 T 29-03-2018 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 Gene3D G3DSA:1.10.1200.10 4658 4710 2.3E-19 T 29-03-2018 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 Gene3D G3DSA:1.10.1200.10 3151 3206 2.8E-20 T 29-03-2018 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 Gene3D G3DSA:3.40.50.980 1716 1877 2.6E-27 T 29-03-2018 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 Gene3D G3DSA:3.40.50.980 4294 4452 7.9E-25 T 29-03-2018 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 Gene3D G3DSA:3.40.50.980 7524 7674 4.3E-32 T 29-03-2018 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 Gene3D G3DSA:3.40.50.980 2788 2939 2.6E-26 T 29-03-2018 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 Gene3D G3DSA:3.40.50.980 5841 5991 3.1E-27 T 29-03-2018 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 Gene3D G3DSA:3.40.50.980 623 779 5.2E-29 T 29-03-2018 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 SUPERFAMILY SSF52777 1266 1508 2.0E-47 T 29-03-2018 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 ProSitePatterns PS00455 Putative AMP-binding domain signature. 617 628 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 ProSitePatterns PS00012 Phosphopantetheine attachment site. 7896 7911 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 Gene3D G3DSA:3.30.559.10 6247 6471 3.8E-44 T 29-03-2018 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 Gene3D G3DSA:3.30.559.10 1056 1285 1.5E-36 T 29-03-2018 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 Gene3D G3DSA:3.30.559.10 5209 5433 2.7E-38 T 29-03-2018 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 Gene3D G3DSA:3.30.559.10 3639 3888 1.6E-36 T 29-03-2018 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 SUPERFAMILY SSF52777 2162 2334 2.67E-47 T 29-03-2018 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1710 1721 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 Pfam PF00668 Condensation domain 3241 3552 1.6E-30 T 29-03-2018 IPR001242 Condensation domain SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 Pfam PF00668 Condensation domain 6268 6721 3.3E-88 T 29-03-2018 IPR001242 Condensation domain SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 Pfam PF00668 Condensation domain 2159 2612 3.0E-84 T 29-03-2018 IPR001242 Condensation domain SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 Pfam PF00668 Condensation domain 5237 5668 3.6E-71 T 29-03-2018 IPR001242 Condensation domain SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 Pfam PF00668 Condensation domain 7974 8327 6.9E-36 T 29-03-2018 IPR001242 Condensation domain SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 Pfam PF00668 Condensation domain 3685 4119 7.6E-73 T 29-03-2018 IPR001242 Condensation domain SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 Pfam PF00668 Condensation domain 6908 7356 4.3E-89 T 29-03-2018 IPR001242 Condensation domain SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 Pfam PF00668 Condensation domain 1083 1519 3.6E-70 T 29-03-2018 IPR001242 Condensation domain SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 Pfam PF00668 Condensation domain 11 435 7.8E-42 T 29-03-2018 IPR001242 Condensation domain SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 Pfam PF00668 Condensation domain 4752 5100 8.7E-27 T 29-03-2018 IPR001242 Condensation domain SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 SMART SM00823 Phosphopantetheine attachment site 6820 6889 5.4E-6 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 SMART SM00823 Phosphopantetheine attachment site 2071 2139 2.8E-8 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 SMART SM00823 Phosphopantetheine attachment site 4651 4719 0.0024 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 SMART SM00823 Phosphopantetheine attachment site 3144 3212 1.8E-4 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 SMART SM00823 Phosphopantetheine attachment site 6184 6253 2.4E-6 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 SMART SM00823 Phosphopantetheine attachment site 985 1053 4.9E-6 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 SMART SM00823 Phosphopantetheine attachment site 7872 7940 5.9E-6 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 SUPERFAMILY SSF56801 464 998 4.97E-133 T 29-03-2018 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 ProSitePatterns PS00455 Putative AMP-binding domain signature. 4288 4299 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 Pfam PF00501 AMP-binding enzyme 5689 6081 4.7E-85 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 Pfam PF00501 AMP-binding enzyme 469 870 3.5E-85 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 Pfam PF00501 AMP-binding enzyme 1567 1969 4.6E-84 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 Pfam PF00501 AMP-binding enzyme 7375 7765 1.6E-87 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 Pfam PF00501 AMP-binding enzyme 2632 3037 1.5E-85 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 Pfam PF00501 AMP-binding enzyme 4143 4542 8.7E-91 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2783 2794 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 SUPERFAMILY SSF56801 7335 7885 6.93E-140 T 29-03-2018 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 Pfam PF13193 AMP-binding enzyme C-terminal domain 4550 4626 1.3E-10 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 Pfam PF13193 AMP-binding enzyme C-terminal domain 3045 3120 5.6E-12 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 Pfam PF13193 AMP-binding enzyme C-terminal domain 7773 7847 1.2E-7 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 Pfam PF13193 AMP-binding enzyme C-terminal domain 878 962 3.5E-9 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 Pfam PF13193 AMP-binding enzyme C-terminal domain 6089 6159 6.6E-11 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 Pfam PF13193 AMP-binding enzyme C-terminal domain 1977 2047 7.5E-14 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 SUPERFAMILY SSF52777 1082 1280 1.22E-37 T 29-03-2018 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 SUPERFAMILY SSF47336 2069 2173 2.49E-18 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 ProSitePatterns PS00455 Putative AMP-binding domain signature. 7518 7529 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 SUPERFAMILY SSF52777 199 431 2.22E-25 T 29-03-2018 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 Gene3D G3DSA:1.10.1200.10 2058 2143 9.3E-24 T 29-03-2018 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 Gene3D G3DSA:1.10.1200.10 6803 6894 3.5E-21 T 29-03-2018 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 SUPERFAMILY SSF52777 5241 5414 9.12E-42 T 29-03-2018 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 Gene3D G3DSA:2.30.38.10 5994 6071 5.4E-23 T 29-03-2018 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 Gene3D G3DSA:2.30.38.10 7675 7755 8.2E-24 T 29-03-2018 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 SUPERFAMILY SSF47336 4644 4713 1.96E-16 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 Gene3D G3DSA:1.10.1200.10 991 1055 2.7E-19 T 29-03-2018 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 Gene3D G3DSA:1.10.1200.10 7878 7938 2.9E-19 T 29-03-2018 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 SUPERFAMILY SSF52777 7093 7363 4.45E-61 T 29-03-2018 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 SUPERFAMILY SSF52777 2347 2596 2.89E-58 T 29-03-2018 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 SUPERFAMILY SSF52777 3219 3393 2.56E-26 T 29-03-2018 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3168 3183 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 SUPERFAMILY SSF52777 5415 5657 7.11E-51 T 29-03-2018 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 SUPERFAMILY SSF56801 5649 6197 2.75E-140 T 29-03-2018 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 SUPERFAMILY SSF52777 7948 8152 3.78E-30 T 29-03-2018 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 Gene3D G3DSA:3.30.300.30 7760 7877 1.4E-26 T 29-03-2018 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 Gene3D G3DSA:3.30.300.30 6076 6189 8.7E-32 T 29-03-2018 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 Gene3D G3DSA:3.30.300.30 4537 4657 2.5E-38 T 29-03-2018 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 Gene3D G3DSA:3.30.300.30 865 990 5.6E-31 T 29-03-2018 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 Gene3D G3DSA:3.30.300.30 3032 3150 1.7E-39 T 29-03-2018 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 SUPERFAMILY SSF52777 3683 3884 2.56E-42 T 29-03-2018 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 SUPERFAMILY SSF52777 6910 7081 1.45E-48 T 29-03-2018 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 SUPERFAMILY SSF47336 6813 6885 6.54E-18 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 4164 4566 8.7E-117 T 29-03-2018 IPR010071 Amino acid adenylation domain SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 7396 7789 1.3E-123 T 29-03-2018 IPR010071 Amino acid adenylation domain SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1585 1991 2.4E-107 T 29-03-2018 IPR010071 Amino acid adenylation domain SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2655 3060 7.3E-120 T 29-03-2018 IPR010071 Amino acid adenylation domain SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 492 893 4.8E-113 T 29-03-2018 IPR010071 Amino acid adenylation domain SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 5712 6105 1.8E-115 T 29-03-2018 IPR010071 Amino acid adenylation domain SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4675 4690 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 Gene3D G3DSA:3.30.559.10 4711 4927 2.2E-21 T 29-03-2018 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 Gene3D G3DSA:3.30.559.10 7939 8166 7.0E-25 T 29-03-2018 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 Gene3D G3DSA:3.30.559.10 3207 3413 2.4E-20 T 29-03-2018 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 Pfam PF00550 Phosphopantetheine attachment site 2073 2135 2.8E-15 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 Pfam PF00550 Phosphopantetheine attachment site 4653 4713 5.7E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 Pfam PF00550 Phosphopantetheine attachment site 3146 3207 2.2E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 Pfam PF00550 Phosphopantetheine attachment site 7874 7934 1.8E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 Pfam PF00550 Phosphopantetheine attachment site 6187 6246 1.1E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 Pfam PF00550 Phosphopantetheine attachment site 988 1048 1.7E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 Pfam PF00550 Phosphopantetheine attachment site 6823 6885 2.2E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 SUPERFAMILY SSF47336 980 1047 5.1E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 SUPERFAMILY SSF47336 3137 3206 7.72E-17 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 SUPERFAMILY SSF47336 7867 7934 1.31E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 SUPERFAMILY SSF56801 4110 4664 1.09E-138 T 29-03-2018 SMALA_RS33435 22761b8d7a5eab5e3d7c109cd32cfa2e 8452 SUPERFAMILY SSF52777 6455 6705 1.33E-57 T 29-03-2018 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 SMART SM00825 Beta-ketoacyl synthase 4497 4923 4.2E-222 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 SMART SM00825 Beta-ketoacyl synthase 3140 3566 4.3E-225 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 SMART SM00825 Beta-ketoacyl synthase 1587 2013 1.4E-221 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 SMART SM00825 Beta-ketoacyl synthase 36 462 2.4E-217 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 SMART SM00825 Beta-ketoacyl synthase 6066 6492 5.5E-223 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 6227 6243 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 SUPERFAMILY SSF51735 7256 7473 7.87E-33 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 SUPERFAMILY SSF51735 2537 2748 7.87E-48 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 ProSitePatterns PS00012 Phosphopantetheine attachment site. 5997 6012 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 412 529 2.5E-12 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 3516 3633 3.5E-14 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 4873 4990 5.0E-15 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1963 2085 4.4E-14 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 6442 6564 3.4E-14 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 SUPERFAMILY SSF52151 2314 2413 5.49E-77 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 SUPERFAMILY SSF52151 2118 2250 5.49E-77 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 SUPERFAMILY SSF53901 6061 6436 5.61E-104 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 3301 3317 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 SUPERFAMILY SSF55048 6730 6794 8.11E-12 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 SUPERFAMILY SSF51735 2758 2987 4.12E-47 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 SUPERFAMILY SSF51735 982 1193 3.67E-50 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 SUPERFAMILY SSF55048 696 760 1.7E-10 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 SUPERFAMILY SSF51735 5686 5919 6.88E-51 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 Gene3D G3DSA:3.30.70.250 6743 6784 1.4E-18 T 29-03-2018 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 Gene3D G3DSA:3.30.70.250 708 756 4.5E-17 T 29-03-2018 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 Gene3D G3DSA:3.30.70.250 2263 2303 3.6E-18 T 29-03-2018 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 Gene3D G3DSA:3.30.70.250 3814 3854 2.2E-18 T 29-03-2018 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 Gene3D G3DSA:3.30.70.250 5167 5214 3.2E-19 T 29-03-2018 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 7624 7645 - T 29-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 Gene3D G3DSA:3.90.180.10 7468 7805 4.2E-60 T 29-03-2018 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 SUPERFAMILY SSF52151 6787 6889 9.94E-75 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 SUPERFAMILY SSF52151 6600 6725 9.94E-75 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 SUPERFAMILY SSF50129 7510 7629 1.56E-25 T 29-03-2018 IPR011032 GroES-like SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 ProSitePatterns PS00012 Phosphopantetheine attachment site. 8124 8139 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 292 409 3.2E-42 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 4753 4870 4.8E-43 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 6322 6439 3.1E-43 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 3397 3513 8.3E-44 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1843 1960 1.2E-42 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 SUPERFAMILY SSF47336 1490 1600 1.7E-22 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 Gene3D G3DSA:3.40.366.10 3855 3971 6.1E-28 T 29-03-2018 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 Gene3D G3DSA:3.40.366.10 6785 6905 9.7E-28 T 29-03-2018 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 Gene3D G3DSA:3.40.366.10 5026 5166 2.9E-41 T 29-03-2018 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 Pfam PF00550 Phosphopantetheine attachment site 4405 4470 1.0E-9 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 Pfam PF00550 Phosphopantetheine attachment site 1494 1559 9.7E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 Pfam PF00550 Phosphopantetheine attachment site 8099 8165 1.8E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 Pfam PF00550 Phosphopantetheine attachment site 5972 6038 2.1E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 Pfam PF00550 Phosphopantetheine attachment site 3048 3114 2.9E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 SUPERFAMILY SSF52151 3669 3801 8.11E-76 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 SUPERFAMILY SSF52151 3865 3959 8.11E-76 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 SUPERFAMILY SSF47336 8090 8178 1.83E-21 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1518 1533 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1748 1764 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 Gene3D G3DSA:3.40.50.720 1199 1457 9.6E-50 T 29-03-2018 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 Gene3D G3DSA:3.40.50.720 7806 8053 4.9E-48 T 29-03-2018 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 Gene3D G3DSA:3.40.50.720 2753 3012 5.8E-54 T 29-03-2018 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 Gene3D G3DSA:3.40.50.720 5680 5939 3.3E-57 T 29-03-2018 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 Gene3D G3DSA:3.40.366.10 2304 2426 1.4E-32 T 29-03-2018 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 Pfam PF00698 Acyl transferase domain 2121 2443 2.3E-59 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 Pfam PF00698 Acyl transferase domain 5027 5346 1.3E-91 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 Pfam PF00698 Acyl transferase domain 3672 3999 2.5E-60 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 Pfam PF00698 Acyl transferase domain 6602 6924 3.5E-60 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 Pfam PF00698 Acyl transferase domain 568 890 1.6E-60 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 SUPERFAMILY SSF47336 5967 6079 1.44E-21 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 SUPERFAMILY SSF51735 1203 1455 1.08E-46 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 Gene3D G3DSA:1.10.1200.10 4339 4484 5.9E-19 T 29-03-2018 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4495 4745 3.7E-94 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1585 1835 5.4E-92 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 284 2.0E-89 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3138 3388 2.4E-92 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 6064 6314 5.7E-91 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 Pfam PF14765 Polyketide synthase dehydratase 4049 4328 7.6E-52 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 Pfam PF14765 Polyketide synthase dehydratase 6974 7245 1.7E-56 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 SMART SM00826 4049 4217 3.4E-72 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 SMART SM00826 6974 7137 1.1E-86 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 SUPERFAMILY SSF47336 4400 4509 1.06E-20 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 SUPERFAMILY SSF53901 31 406 5.62E-101 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 SUPERFAMILY SSF55048 2249 2313 2.75E-11 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 Gene3D G3DSA:1.10.1200.10 1486 1584 4.1E-19 T 29-03-2018 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 Gene3D G3DSA:1.10.1200.10 3041 3136 1.8E-18 T 29-03-2018 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 SUPERFAMILY SSF52151 565 697 9.94E-77 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 SUPERFAMILY SSF52151 761 858 9.94E-77 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2122 2424 7.5E-134 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 5029 5327 8.8E-124 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 3673 3982 1.1E-134 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 569 871 4.6E-132 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 6603 6906 3.1E-135 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 SUPERFAMILY SSF53901 1581 1957 1.73E-102 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 Gene3D G3DSA:3.10.129.10 6976 7093 6.2E-7 T 29-03-2018 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 Gene3D G3DSA:3.10.129.10 4055 4177 5.1E-4 T 29-03-2018 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 Pfam PF13602 Zinc-binding dehydrogenase 7671 7802 4.9E-16 T 29-03-2018 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 SUPERFAMILY SSF55048 5153 5218 1.01E-13 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 SUPERFAMILY SSF47336 3044 3153 3.14E-23 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 4658 4674 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 Gene3D G3DSA:3.40.366.10 562 707 1.1E-49 T 29-03-2018 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 Gene3D G3DSA:3.40.366.10 2115 2262 1.1E-50 T 29-03-2018 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 Gene3D G3DSA:3.40.366.10 3666 3813 4.6E-50 T 29-03-2018 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 Gene3D G3DSA:3.40.366.10 6596 6742 5.7E-49 T 29-03-2018 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 SUPERFAMILY SSF53901 3134 3510 2.96E-107 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 Gene3D G3DSA:1.10.1200.10 5942 6047 6.9E-18 T 29-03-2018 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 Gene3D G3DSA:1.10.1200.10 8059 8176 1.5E-19 T 29-03-2018 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 SUPERFAMILY SSF51735 5441 5675 9.05E-40 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 SMART SM00829 7496 7802 1.7E-183 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 SUPERFAMILY SSF101173 3 33 7.85E-6 T 29-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 SUPERFAMILY SSF51735 7596 7773 1.21E-37 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 Gene3D G3DSA:3.40.47.10 4488 4757 1.4E-88 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 Gene3D G3DSA:3.40.47.10 1585 1847 2.3E-89 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 Gene3D G3DSA:3.40.47.10 6057 6326 4.2E-85 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 Gene3D G3DSA:3.40.47.10 3137 3400 5.3E-89 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 Gene3D G3DSA:3.40.47.10 26 296 2.4E-86 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 SUPERFAMILY SSF51735 7809 8022 8.53E-45 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 SUPERFAMILY SSF52151 5026 5154 2.38E-67 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 SUPERFAMILY SSF52151 5219 5317 2.38E-67 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 SMART SM01294 4404 4471 1.6E-4 T 29-03-2018 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 SMART SM01294 5971 6038 6.1E-5 T 29-03-2018 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 SMART SM01294 1492 1559 7.1E-6 T 29-03-2018 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 SMART SM01294 3047 3114 6.0E-7 T 29-03-2018 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 SMART SM01294 8098 8165 2.6E-5 T 29-03-2018 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 SMART SM00823 Phosphopantetheine attachment site 3046 3118 1.6E-31 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 SMART SM00823 Phosphopantetheine attachment site 5970 6042 1.5E-28 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 SMART SM00823 Phosphopantetheine attachment site 4403 4475 6.8E-29 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 SMART SM00823 Phosphopantetheine attachment site 8097 8169 1.0E-32 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 SMART SM00823 Phosphopantetheine attachment site 1491 1563 3.9E-28 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 Gene3D G3DSA:3.40.47.10 3403 3564 6.7E-62 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 Gene3D G3DSA:3.40.47.10 299 460 4.3E-60 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 Gene3D G3DSA:3.40.47.10 6329 6490 7.1E-61 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 Gene3D G3DSA:3.40.47.10 1850 2011 1.8E-60 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 Gene3D G3DSA:3.40.47.10 4760 4921 5.8E-60 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 Gene3D G3DSA:3.40.366.10 757 872 2.3E-28 T 29-03-2018 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 Gene3D G3DSA:3.40.366.10 5215 5329 1.8E-26 T 29-03-2018 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 Pfam PF08990 Erythronolide synthase docking 3 27 7.9E-13 T 29-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 197 213 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 SUPERFAMILY SSF53901 4492 4868 3.55E-102 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 SUPERFAMILY SSF55048 3800 3864 2.35E-11 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1207 1420 1.6E-57 T 29-03-2018 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2761 2940 4.3E-56 T 29-03-2018 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5688 5867 3.4E-58 T 29-03-2018 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7812 7992 2.3E-64 T 29-03-2018 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 Pfam PF08659 KR domain 7812 7990 3.5E-58 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 Pfam PF08659 KR domain 1207 1385 1.8E-57 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 Pfam PF08659 KR domain 5688 5865 6.6E-59 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37835 4d640514bfd3d3370ed63a45c2db6dd6 8259 Pfam PF08659 KR domain 2761 2939 2.6E-58 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS25660 1289cee9bc33187ee8f7ee7768920824 375 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 240 341 3.7E-24 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMALA_RS25660 1289cee9bc33187ee8f7ee7768920824 375 SMART SM00382 48 240 4.0E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS25660 1289cee9bc33187ee8f7ee7768920824 375 SUPERFAMILY SSF52540 29 261 2.32E-72 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS25660 1289cee9bc33187ee8f7ee7768920824 375 Pfam PF00005 ABC transporter 40 190 4.2E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS25660 1289cee9bc33187ee8f7ee7768920824 375 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 242 318 1.4E-14 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMALA_RS25660 1289cee9bc33187ee8f7ee7768920824 375 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS25660 1289cee9bc33187ee8f7ee7768920824 375 Gene3D G3DSA:3.40.50.300 8 356 3.1E-79 T 29-03-2018 SMALA_RS10245 f4eba304afaa1fa07a20c2f72cda291d 660 Pfam PF03717 Penicillin-binding Protein dimerisation domain 108 270 1.6E-16 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 SMALA_RS10245 f4eba304afaa1fa07a20c2f72cda291d 660 SUPERFAMILY SSF56519 105 293 9.94E-34 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 SMALA_RS10245 f4eba304afaa1fa07a20c2f72cda291d 660 Pfam PF00905 Penicillin binding protein transpeptidase domain 319 634 1.4E-70 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 SMALA_RS10245 f4eba304afaa1fa07a20c2f72cda291d 660 Gene3D G3DSA:3.40.710.10 291 641 1.6E-81 T 29-03-2018 SMALA_RS10245 f4eba304afaa1fa07a20c2f72cda291d 660 Gene3D G3DSA:3.90.1310.10 76 290 1.3E-37 T 29-03-2018 SMALA_RS10245 f4eba304afaa1fa07a20c2f72cda291d 660 SUPERFAMILY SSF56601 294 642 2.82E-81 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMALA_RS23450 c20a0cd8de67b91774734304d867aed4 318 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 108 307 3.6E-14 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS23450 c20a0cd8de67b91774734304d867aed4 318 SUPERFAMILY SSF161098 77 303 3.92E-54 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS23450 c20a0cd8de67b91774734304d867aed4 318 Gene3D G3DSA:1.10.3720.10 36 315 5.7E-52 T 29-03-2018 SMALA_RS38435 cde44e9f959571b068c468a0f32e14a2 321 Pfam PF00892 EamA-like transporter family 150 283 4.5E-14 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SMALA_RS38435 cde44e9f959571b068c468a0f32e14a2 321 Pfam PF00892 EamA-like transporter family 1 127 3.9E-7 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SMALA_RS38435 cde44e9f959571b068c468a0f32e14a2 321 SUPERFAMILY SSF103481 187 286 8.63E-13 T 29-03-2018 SMALA_RS38435 cde44e9f959571b068c468a0f32e14a2 321 SUPERFAMILY SSF103481 49 129 1.2E-5 T 29-03-2018 SMALA_RS18240 06488c3b7e2e9dca5cf33f19b0976503 181 Gene3D G3DSA:1.10.1740.10 3 76 4.6E-16 T 29-03-2018 SMALA_RS18240 06488c3b7e2e9dca5cf33f19b0976503 181 Pfam PF08281 Sigma-70, region 4 113 165 4.7E-16 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS18240 06488c3b7e2e9dca5cf33f19b0976503 181 Pfam PF04542 Sigma-70 region 2 23 80 1.8E-17 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS18240 06488c3b7e2e9dca5cf33f19b0976503 181 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 37 67 - T 29-03-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS18240 06488c3b7e2e9dca5cf33f19b0976503 181 Gene3D G3DSA:1.10.10.10 77 172 3.8E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS18240 06488c3b7e2e9dca5cf33f19b0976503 181 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 21 169 1.1E-28 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS18240 06488c3b7e2e9dca5cf33f19b0976503 181 SUPERFAMILY SSF88659 107 169 2.16E-15 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS18240 06488c3b7e2e9dca5cf33f19b0976503 181 SUPERFAMILY SSF88946 8 94 2.35E-17 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS26020 d0c3c2ff38a4e5f7f44e6f77ac620f7b 751 Pfam PF00570 HRDC domain 667 732 8.5E-20 T 29-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 SMALA_RS26020 d0c3c2ff38a4e5f7f44e6f77ac620f7b 751 Gene3D G3DSA:3.40.50.300 27 299 2.1E-48 T 29-03-2018 SMALA_RS26020 d0c3c2ff38a4e5f7f44e6f77ac620f7b 751 SUPERFAMILY SSF52540 29 600 2.05E-117 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS26020 d0c3c2ff38a4e5f7f44e6f77ac620f7b 751 Pfam PF13361 UvrD-like helicase C-terminal domain 473 580 8.3E-24 T 29-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 SMALA_RS26020 d0c3c2ff38a4e5f7f44e6f77ac620f7b 751 Pfam PF13361 UvrD-like helicase C-terminal domain 303 430 8.6E-13 T 29-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 SMALA_RS26020 d0c3c2ff38a4e5f7f44e6f77ac620f7b 751 SMART SM00341 663 743 7.0E-15 T 29-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 SMALA_RS26020 d0c3c2ff38a4e5f7f44e6f77ac620f7b 751 Pfam PF13245 AAA domain 37 281 1.5E-35 T 29-03-2018 SMALA_RS26020 d0c3c2ff38a4e5f7f44e6f77ac620f7b 751 SUPERFAMILY SSF47819 656 735 3.49E-20 T 29-03-2018 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 SMALA_RS26020 d0c3c2ff38a4e5f7f44e6f77ac620f7b 751 Gene3D G3DSA:3.40.50.300 300 608 3.7E-52 T 29-03-2018 SMALA_RS26020 d0c3c2ff38a4e5f7f44e6f77ac620f7b 751 Gene3D G3DSA:1.10.150.80 650 735 2.0E-20 T 29-03-2018 SMALA_RS08245 2d99b9a158ddacf2cc97377812665b12 318 Gene3D G3DSA:3.10.450.50 168 309 2.0E-20 T 29-03-2018 SMALA_RS08245 2d99b9a158ddacf2cc97377812665b12 318 SUPERFAMILY SSF54427 189 308 8.36E-14 T 29-03-2018 IPR032710 NTF2-like domain SMALA_RS08245 2d99b9a158ddacf2cc97377812665b12 318 SUPERFAMILY SSF88946 25 110 2.43E-13 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS08245 2d99b9a158ddacf2cc97377812665b12 318 SUPERFAMILY SSF88659 100 180 3.92E-12 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS08245 2d99b9a158ddacf2cc97377812665b12 318 Pfam PF04542 Sigma-70 region 2 31 92 1.3E-13 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS08245 2d99b9a158ddacf2cc97377812665b12 318 Gene3D G3DSA:1.10.1740.10 20 89 8.0E-14 T 29-03-2018 SMALA_RS08245 2d99b9a158ddacf2cc97377812665b12 318 Gene3D G3DSA:1.10.10.10 90 167 3.2E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS08245 2d99b9a158ddacf2cc97377812665b12 318 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 28 177 5.6E-16 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS08245 2d99b9a158ddacf2cc97377812665b12 318 Pfam PF12680 SnoaL-like domain 195 281 1.4E-7 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain SMALA_RS08245 2d99b9a158ddacf2cc97377812665b12 318 Pfam PF08281 Sigma-70, region 4 125 175 3.3E-12 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS12235 d38cf22c7db07713d980768874a7ba8d 321 Gene3D G3DSA:1.10.10.60 134 239 3.2E-14 T 29-03-2018 SMALA_RS12235 d38cf22c7db07713d980768874a7ba8d 321 Pfam PF06719 AraC-type transcriptional regulator N-terminus 31 172 6.0E-42 T 29-03-2018 IPR009594 Transcription regulator HTH, AraC, N-terminal SMALA_RS12235 d38cf22c7db07713d980768874a7ba8d 321 Pfam PF12833 Helix-turn-helix domain 207 282 6.0E-21 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS12235 d38cf22c7db07713d980768874a7ba8d 321 SMART SM00342 201 284 1.1E-25 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS12235 d38cf22c7db07713d980768874a7ba8d 321 SUPERFAMILY SSF46689 237 282 3.81E-9 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS12235 d38cf22c7db07713d980768874a7ba8d 321 Gene3D G3DSA:1.10.10.60 240 291 6.6E-12 T 29-03-2018 SMALA_RS12235 d38cf22c7db07713d980768874a7ba8d 321 SUPERFAMILY SSF46689 186 235 5.84E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS35970 e5e90955280789180f483b7bb99b0ba4 1657 SUPERFAMILY SSF51735 973 1205 1.38E-43 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS35970 e5e90955280789180f483b7bb99b0ba4 1657 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 290 407 2.1E-43 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS35970 e5e90955280789180f483b7bb99b0ba4 1657 SMART SM00825 Beta-ketoacyl synthase 34 460 7.9E-210 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS35970 e5e90955280789180f483b7bb99b0ba4 1657 Pfam PF00698 Acyl transferase domain 567 879 1.7E-84 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS35970 e5e90955280789180f483b7bb99b0ba4 1657 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1219 1399 3.7E-51 T 29-03-2018 SMALA_RS35970 e5e90955280789180f483b7bb99b0ba4 1657 Gene3D G3DSA:3.40.47.10 24 294 4.0E-81 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS35970 e5e90955280789180f483b7bb99b0ba4 1657 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1534 1549 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS35970 e5e90955280789180f483b7bb99b0ba4 1657 SUPERFAMILY SSF55048 690 755 1.09E-14 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS35970 e5e90955280789180f483b7bb99b0ba4 1657 SMART SM00823 Phosphopantetheine attachment site 1507 1579 1.4E-31 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS35970 e5e90955280789180f483b7bb99b0ba4 1657 SUPERFAMILY SSF53901 28 405 2.39E-100 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS35970 e5e90955280789180f483b7bb99b0ba4 1657 Pfam PF08990 Erythronolide synthase docking 3 27 5.5E-9 T 29-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 SMALA_RS35970 e5e90955280789180f483b7bb99b0ba4 1657 SMART SM01294 1508 1575 8.3E-5 T 29-03-2018 SMALA_RS35970 e5e90955280789180f483b7bb99b0ba4 1657 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 32 282 5.1E-86 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS35970 e5e90955280789180f483b7bb99b0ba4 1657 Gene3D G3DSA:3.40.47.10 297 458 5.2E-61 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS35970 e5e90955280789180f483b7bb99b0ba4 1657 SUPERFAMILY SSF51735 1214 1482 8.73E-52 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS35970 e5e90955280789180f483b7bb99b0ba4 1657 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 410 532 5.1E-13 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS35970 e5e90955280789180f483b7bb99b0ba4 1657 Gene3D G3DSA:3.40.366.10 748 867 4.3E-24 T 29-03-2018 SMALA_RS35970 e5e90955280789180f483b7bb99b0ba4 1657 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 569 860 9.8E-114 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS35970 e5e90955280789180f483b7bb99b0ba4 1657 Gene3D G3DSA:3.30.70.250 705 747 1.6E-20 T 29-03-2018 SMALA_RS35970 e5e90955280789180f483b7bb99b0ba4 1657 Gene3D G3DSA:3.40.366.10 566 704 2.2E-38 T 29-03-2018 SMALA_RS35970 e5e90955280789180f483b7bb99b0ba4 1657 SUPERFAMILY SSF47336 1505 1588 1.09E-20 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS35970 e5e90955280789180f483b7bb99b0ba4 1657 Pfam PF08659 KR domain 1219 1397 1.1E-56 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS35970 e5e90955280789180f483b7bb99b0ba4 1657 Gene3D G3DSA:1.10.1200.10 1501 1637 1.8E-19 T 29-03-2018 SMALA_RS35970 e5e90955280789180f483b7bb99b0ba4 1657 SUPERFAMILY SSF52151 756 849 2.88E-62 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS35970 e5e90955280789180f483b7bb99b0ba4 1657 SUPERFAMILY SSF52151 565 691 2.88E-62 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS35970 e5e90955280789180f483b7bb99b0ba4 1657 Pfam PF00550 Phosphopantetheine attachment site 1510 1575 1.1E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS35970 e5e90955280789180f483b7bb99b0ba4 1657 Gene3D G3DSA:3.40.50.720 1213 1473 5.5E-56 T 29-03-2018 SMALA_RS16815 cf23400b70937255d9bd8fe2f9c4055b 500 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 251 258 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 SMALA_RS16815 cf23400b70937255d9bd8fe2f9c4055b 500 Pfam PF00171 Aldehyde dehydrogenase family 13 486 8.5E-162 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS16815 cf23400b70937255d9bd8fe2f9c4055b 500 Gene3D G3DSA:3.40.605.10 2 269 1.4E-87 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS16815 cf23400b70937255d9bd8fe2f9c4055b 500 SUPERFAMILY SSF53720 7 491 8.51E-155 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMALA_RS16815 cf23400b70937255d9bd8fe2f9c4055b 500 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 284 295 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 SMALA_RS16815 cf23400b70937255d9bd8fe2f9c4055b 500 Gene3D G3DSA:3.40.309.10 270 472 7.9E-68 T 29-03-2018 SMALA_RS10230 0076625ae4f36aab999b3e1493384e90 355 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 3 349 23.827 T 29-03-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 SMALA_RS10230 0076625ae4f36aab999b3e1493384e90 355 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 46 55 6.2E-4 T 29-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 SMALA_RS10230 0076625ae4f36aab999b3e1493384e90 355 Pfam PF00953 Glycosyl transferase family 4 82 275 2.0E-36 T 29-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 SMALA_RS10230 0076625ae4f36aab999b3e1493384e90 355 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 17 345 2.4E-98 T 29-03-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 SMALA_RS10230 0076625ae4f36aab999b3e1493384e90 355 ProSitePatterns PS01348 MraY family signature 2. 174 185 - T 29-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 SMALA_RS10230 0076625ae4f36aab999b3e1493384e90 355 ProSitePatterns PS01347 MraY family signature 1. 46 58 - T 29-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 SMALA_RS21870 1b920ffad34c59b7543fc9660b8ca376 583 SUPERFAMILY SSF48163 373 581 1.7E-22 T 29-03-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 SMALA_RS21870 1b920ffad34c59b7543fc9660b8ca376 583 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 47 56 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMALA_RS21870 1b920ffad34c59b7543fc9660b8ca376 583 Gene3D G3DSA:1.10.10.350 483 583 1.9E-14 T 29-03-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 SMALA_RS21870 1b920ffad34c59b7543fc9660b8ca376 583 TIGRFAM TIGR00467 lysS_arch: lysine--tRNA ligase 219 581 1.4E-55 T 29-03-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 SMALA_RS21870 1b920ffad34c59b7543fc9660b8ca376 583 Gene3D G3DSA:3.40.50.620 15 320 4.5E-42 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS21870 1b920ffad34c59b7543fc9660b8ca376 583 Pfam PF01921 tRNA synthetases class I (K) 17 406 5.5E-127 T 29-03-2018 SMALA_RS21870 1b920ffad34c59b7543fc9660b8ca376 583 Gene3D G3DSA:3.40.50.620 321 410 1.9E-5 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS21870 1b920ffad34c59b7543fc9660b8ca376 583 SUPERFAMILY SSF52374 30 203 3.18E-50 T 29-03-2018 SMALA_RS21870 1b920ffad34c59b7543fc9660b8ca376 583 SUPERFAMILY SSF52374 254 367 3.18E-50 T 29-03-2018 SMALA_RS21870 1b920ffad34c59b7543fc9660b8ca376 583 Hamap MF_00177 Lysine--tRNA ligase [lysS]. 16 583 30.829 T 29-03-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 SMALA_RS10145 474de31fba4fb10e5f0fec14e27800d7 196 Gene3D G3DSA:3.40.50.1820 2 195 3.1E-20 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS10145 474de31fba4fb10e5f0fec14e27800d7 196 SUPERFAMILY SSF53474 8 194 6.99E-29 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS10145 474de31fba4fb10e5f0fec14e27800d7 196 Pfam PF01738 Dienelactone hydrolase family 8 194 1.2E-23 T 29-03-2018 IPR002925 Dienelactone hydrolase GO:0016787 SMALA_RS11690 68518de24a9d4d2db5a7ea3b82b76bb4 260 SUPERFAMILY SSF53474 12 256 8.78E-47 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS11690 68518de24a9d4d2db5a7ea3b82b76bb4 260 PRINTS PR00111 Alpha/beta hydrolase fold signature 46 61 8.8E-7 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS11690 68518de24a9d4d2db5a7ea3b82b76bb4 260 PRINTS PR00111 Alpha/beta hydrolase fold signature 104 117 8.8E-7 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS11690 68518de24a9d4d2db5a7ea3b82b76bb4 260 PRINTS PR00111 Alpha/beta hydrolase fold signature 90 103 8.8E-7 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS11690 68518de24a9d4d2db5a7ea3b82b76bb4 260 Gene3D G3DSA:3.40.50.1820 8 258 1.4E-42 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS11690 68518de24a9d4d2db5a7ea3b82b76bb4 260 PRINTS PR00412 Epoxide hydrolase signature 46 61 3.0E-7 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS11690 68518de24a9d4d2db5a7ea3b82b76bb4 260 PRINTS PR00412 Epoxide hydrolase signature 233 255 3.0E-7 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS11690 68518de24a9d4d2db5a7ea3b82b76bb4 260 Pfam PF00561 alpha/beta hydrolase fold 23 137 6.1E-20 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS13685 55435d2b6083d0c0cbcf932245031fb6 248 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 193 0.0079 T 29-03-2018 SMALA_RS13685 55435d2b6083d0c0cbcf932245031fb6 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 4.5E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS13685 55435d2b6083d0c0cbcf932245031fb6 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 4.5E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS13685 55435d2b6083d0c0cbcf932245031fb6 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 4.5E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS13685 55435d2b6083d0c0cbcf932245031fb6 248 SUPERFAMILY SSF51735 5 246 1.03E-71 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS13685 55435d2b6083d0c0cbcf932245031fb6 248 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 246 3.4E-54 T 29-03-2018 SMALA_RS13685 55435d2b6083d0c0cbcf932245031fb6 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 3.0E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS13685 55435d2b6083d0c0cbcf932245031fb6 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 3.0E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS13685 55435d2b6083d0c0cbcf932245031fb6 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 3.0E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS13685 55435d2b6083d0c0cbcf932245031fb6 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 3.0E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS13685 55435d2b6083d0c0cbcf932245031fb6 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 3.0E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS13685 55435d2b6083d0c0cbcf932245031fb6 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 3.0E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS13685 55435d2b6083d0c0cbcf932245031fb6 248 Gene3D G3DSA:3.40.50.720 39 248 5.5E-56 T 29-03-2018 SMALA_RS13685 55435d2b6083d0c0cbcf932245031fb6 248 Gene3D G3DSA:3.40.50.720 1 38 5.5E-9 T 29-03-2018 SMALA_RS20820 ed587d822c612d447e487364923542f3 601 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 21 43 - T 29-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 SMALA_RS20820 ed587d822c612d447e487364923542f3 601 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 134 146 - T 29-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMALA_RS20820 ed587d822c612d447e487364923542f3 601 Gene3D G3DSA:3.30.200.20 2 112 2.3E-14 T 29-03-2018 SMALA_RS20820 ed587d822c612d447e487364923542f3 601 SUPERFAMILY SSF56112 11 275 6.47E-61 T 29-03-2018 IPR011009 Protein kinase-like domain SMALA_RS20820 ed587d822c612d447e487364923542f3 601 SMART SM00220 15 276 4.9E-45 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMALA_RS20820 ed587d822c612d447e487364923542f3 601 Pfam PF00069 Protein kinase domain 15 270 1.1E-37 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMALA_RS20820 ed587d822c612d447e487364923542f3 601 Pfam PF14219 Domain of unknown function (DUF4328) 423 575 1.3E-30 T 29-03-2018 IPR025565 Domain of unknown function DUF4328 SMALA_RS20820 ed587d822c612d447e487364923542f3 601 Gene3D G3DSA:1.10.510.10 113 463 1.2E-38 T 29-03-2018 SMALA_RS41605 7420994c2d05664b262eb545b34c400d 841 Gene3D G3DSA:3.30.450.20 180 297 5.5E-14 T 29-03-2018 SMALA_RS41605 7420994c2d05664b262eb545b34c400d 841 Pfam PF13185 GAF domain 323 464 2.3E-12 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS41605 7420994c2d05664b262eb545b34c400d 841 Gene3D G3DSA:3.30.565.10 723 841 1.6E-9 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS41605 7420994c2d05664b262eb545b34c400d 841 SMART SM00331 494 714 9.2E-37 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS41605 7420994c2d05664b262eb545b34c400d 841 Pfam PF08448 PAS fold 189 292 8.9E-9 T 29-03-2018 IPR013656 PAS fold-4 SMALA_RS41605 7420994c2d05664b262eb545b34c400d 841 SUPERFAMILY SSF55785 194 296 1.13E-6 T 29-03-2018 IPR000014 PAS domain SMALA_RS41605 7420994c2d05664b262eb545b34c400d 841 Gene3D G3DSA:3.30.450.40 298 469 7.9E-25 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS41605 7420994c2d05664b262eb545b34c400d 841 SUPERFAMILY SSF55781 327 474 2.62E-14 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS41605 7420994c2d05664b262eb545b34c400d 841 SUPERFAMILY SSF81606 509 668 2.88E-8 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS41605 7420994c2d05664b262eb545b34c400d 841 Gene3D G3DSA:3.60.40.10 470 717 1.9E-40 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS41605 7420994c2d05664b262eb545b34c400d 841 Gene3D G3DSA:3.30.450.40 4 160 0.0044 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS41605 7420994c2d05664b262eb545b34c400d 841 SUPERFAMILY SSF55874 736 835 9.63E-5 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS41605 7420994c2d05664b262eb545b34c400d 841 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 521 714 2.2E-51 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS12295 6905f3ae15a1acb5e0bb7337e3f4ffd7 109 SUPERFAMILY SSF57716 76 107 4.56E-7 T 29-03-2018 SMALA_RS12295 6905f3ae15a1acb5e0bb7337e3f4ffd7 109 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 74 107 6.3E-11 T 29-03-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 SMALA_RS30945 51fc1dcdf2091e212edfab617b55d099 703 Pfam PF00326 Prolyl oligopeptidase family 474 678 9.5E-42 T 29-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 SMALA_RS30945 51fc1dcdf2091e212edfab617b55d099 703 Gene3D G3DSA:2.140.10.30 227 415 9.9E-8 T 29-03-2018 SMALA_RS30945 51fc1dcdf2091e212edfab617b55d099 703 Gene3D G3DSA:2.140.10.30 2 226 1.0E-11 T 29-03-2018 SMALA_RS30945 51fc1dcdf2091e212edfab617b55d099 703 SUPERFAMILY SSF53474 425 671 3.09E-56 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS30945 51fc1dcdf2091e212edfab617b55d099 703 SUPERFAMILY SSF82171 99 279 3.14E-11 T 29-03-2018 SMALA_RS30945 51fc1dcdf2091e212edfab617b55d099 703 SUPERFAMILY SSF82171 313 403 3.14E-11 T 29-03-2018 SMALA_RS30945 51fc1dcdf2091e212edfab617b55d099 703 Gene3D G3DSA:3.40.50.1820 416 673 3.1E-42 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS16750 1edcd4d0a57e8e8552b74783d5b59058 337 SUPERFAMILY SSF52374 7 332 2.66E-96 T 29-03-2018 SMALA_RS16750 1edcd4d0a57e8e8552b74783d5b59058 337 Gene3D G3DSA:3.40.50.620 1 194 7.6E-75 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS16750 1edcd4d0a57e8e8552b74783d5b59058 337 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 19 35 3.3E-26 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 SMALA_RS16750 1edcd4d0a57e8e8552b74783d5b59058 337 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 69 88 3.3E-26 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 SMALA_RS16750 1edcd4d0a57e8e8552b74783d5b59058 337 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 146 167 3.3E-26 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 SMALA_RS16750 1edcd4d0a57e8e8552b74783d5b59058 337 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 199 209 3.3E-26 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 SMALA_RS16750 1edcd4d0a57e8e8552b74783d5b59058 337 Gene3D G3DSA:1.10.240.10 195 315 7.5E-31 T 29-03-2018 SMALA_RS16750 1edcd4d0a57e8e8552b74783d5b59058 337 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 5 333 41.848 T 29-03-2018 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 SMALA_RS16750 1edcd4d0a57e8e8552b74783d5b59058 337 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 5 332 6.0E-104 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 SMALA_RS16750 1edcd4d0a57e8e8552b74783d5b59058 337 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 14 24 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMALA_RS16750 1edcd4d0a57e8e8552b74783d5b59058 337 Pfam PF00579 tRNA synthetases class I (W and Y) 5 285 1.3E-76 T 29-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMALA_RS28405 ae312a482a6aeeaef32cbc3af538340f 338 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 4.0E-18 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS28405 ae312a482a6aeeaef32cbc3af538340f 338 Gene3D G3DSA:3.40.50.2300 181 337 1.8E-28 T 29-03-2018 SMALA_RS28405 ae312a482a6aeeaef32cbc3af538340f 338 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 29-03-2018 SMALA_RS28405 ae312a482a6aeeaef32cbc3af538340f 338 SUPERFAMILY SSF47413 1 60 1.66E-17 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS28405 ae312a482a6aeeaef32cbc3af538340f 338 Gene3D G3DSA:1.10.260.40 2 57 2.4E-22 T 29-03-2018 SMALA_RS28405 ae312a482a6aeeaef32cbc3af538340f 338 SUPERFAMILY SSF53822 58 319 4.71E-34 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SMALA_RS28405 ae312a482a6aeeaef32cbc3af538340f 338 Gene3D G3DSA:3.40.50.2300 58 180 1.1E-25 T 29-03-2018 SMALA_RS28405 ae312a482a6aeeaef32cbc3af538340f 338 SMART SM00354 1 71 3.0E-27 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS28405 ae312a482a6aeeaef32cbc3af538340f 338 Pfam PF13377 Periplasmic binding protein-like domain 168 331 6.0E-28 T 29-03-2018 SMALA_RS29670 6c90d1a932eea853daf2a51850cea9dc 246 Gene3D G3DSA:1.20.120.530 91 243 6.8E-28 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS29670 6c90d1a932eea853daf2a51850cea9dc 246 Pfam PF07729 FCD domain 105 224 2.4E-23 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS29670 6c90d1a932eea853daf2a51850cea9dc 246 SMART SM00345 13 71 1.0E-8 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS29670 6c90d1a932eea853daf2a51850cea9dc 246 Gene3D G3DSA:1.10.10.10 3 85 1.3E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS29670 6c90d1a932eea853daf2a51850cea9dc 246 SUPERFAMILY SSF48008 105 230 8.89E-24 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS29670 6c90d1a932eea853daf2a51850cea9dc 246 SUPERFAMILY SSF46785 3 75 7.06E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS29670 6c90d1a932eea853daf2a51850cea9dc 246 SMART SM00895 104 225 7.5E-23 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS29670 6c90d1a932eea853daf2a51850cea9dc 246 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 71 1.7E-11 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS26585 06e4a784e51d7db9f6a38a0114059336 806 SMART SM00382 359 504 1.7E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS26585 06e4a784e51d7db9f6a38a0114059336 806 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 582 792 8.2E-76 T 29-03-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 SMALA_RS26585 06e4a784e51d7db9f6a38a0114059336 806 Gene3D G3DSA:1.10.8.60 503 596 5.3E-26 T 29-03-2018 SMALA_RS26585 06e4a784e51d7db9f6a38a0114059336 806 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 696 704 - T 29-03-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 SMALA_RS26585 06e4a784e51d7db9f6a38a0114059336 806 Gene3D G3DSA:3.40.50.300 315 502 8.7E-32 T 29-03-2018 SMALA_RS26585 06e4a784e51d7db9f6a38a0114059336 806 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 612 628 9.8E-51 T 29-03-2018 SMALA_RS26585 06e4a784e51d7db9f6a38a0114059336 806 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 723 742 9.8E-51 T 29-03-2018 SMALA_RS26585 06e4a784e51d7db9f6a38a0114059336 806 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 746 764 9.8E-51 T 29-03-2018 SMALA_RS26585 06e4a784e51d7db9f6a38a0114059336 806 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 693 712 9.8E-51 T 29-03-2018 SMALA_RS26585 06e4a784e51d7db9f6a38a0114059336 806 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 367 386 9.8E-51 T 29-03-2018 SMALA_RS26585 06e4a784e51d7db9f6a38a0114059336 806 SMART SM00464 9 203 6.2E-20 T 29-03-2018 IPR003111 Lon, substrate-binding domain SMALA_RS26585 06e4a784e51d7db9f6a38a0114059336 806 Gene3D G3DSA:1.10.4060.10 124 210 2.5E-8 T 29-03-2018 SMALA_RS26585 06e4a784e51d7db9f6a38a0114059336 806 Gene3D G3DSA:3.30.230.10 602 792 1.1E-60 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SMALA_RS26585 06e4a784e51d7db9f6a38a0114059336 806 SUPERFAMILY SSF52540 310 567 5.16E-50 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS26585 06e4a784e51d7db9f6a38a0114059336 806 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 9 202 4.5E-17 T 29-03-2018 IPR003111 Lon, substrate-binding domain SMALA_RS26585 06e4a784e51d7db9f6a38a0114059336 806 PIRSF PIRSF001174 1 795 5.3E-247 T 29-03-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 SMALA_RS26585 06e4a784e51d7db9f6a38a0114059336 806 Hamap MF_01973 Lon protease [lon]. 10 792 59.211 T 29-03-2018 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 SMALA_RS26585 06e4a784e51d7db9f6a38a0114059336 806 TIGRFAM TIGR00763 lon: endopeptidase La 11 791 5.2E-241 T 29-03-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 SMALA_RS26585 06e4a784e51d7db9f6a38a0114059336 806 Gene3D G3DSA:2.30.130.40 2 116 1.4E-17 T 29-03-2018 SMALA_RS26585 06e4a784e51d7db9f6a38a0114059336 806 SUPERFAMILY SSF88697 9 201 3.48E-23 T 29-03-2018 IPR015947 PUA-like domain SMALA_RS26585 06e4a784e51d7db9f6a38a0114059336 806 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 364 499 2.4E-20 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 SMALA_RS26585 06e4a784e51d7db9f6a38a0114059336 806 SUPERFAMILY SSF54211 612 790 1.25E-51 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SMALA_RS18795 3de2700a7213ae5255f4e1d772974018 868 Gene3D G3DSA:1.20.272.10 246 368 4.8E-22 T 29-03-2018 SMALA_RS18795 3de2700a7213ae5255f4e1d772974018 868 SUPERFAMILY SSF52540 32 222 1.5E-50 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS18795 3de2700a7213ae5255f4e1d772974018 868 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 236 365 6.3E-13 T 29-03-2018 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 SMALA_RS18795 3de2700a7213ae5255f4e1d772974018 868 Gene3D G3DSA:1.10.8.60 169 245 5.0E-9 T 29-03-2018 SMALA_RS18795 3de2700a7213ae5255f4e1d772974018 868 Pfam PF13177 DNA polymerase III, delta subunit 20 178 7.4E-38 T 29-03-2018 SMALA_RS18795 3de2700a7213ae5255f4e1d772974018 868 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 5 363 3.8E-116 T 29-03-2018 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 SMALA_RS18795 3de2700a7213ae5255f4e1d772974018 868 SUPERFAMILY SSF48019 247 365 3.66E-21 T 29-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 SMALA_RS18795 3de2700a7213ae5255f4e1d772974018 868 SMART SM00382 37 181 3.6E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS18795 3de2700a7213ae5255f4e1d772974018 868 Gene3D G3DSA:3.40.50.300 2 168 1.2E-35 T 29-03-2018 SMALA_RS35465 1eca60160c6fa930d9acf418e2de61ae 253 Pfam PF00455 DeoR C terminal sensor domain 75 233 3.0E-44 T 29-03-2018 IPR014036 DeoR C-terminal sensor domain SMALA_RS35465 1eca60160c6fa930d9acf418e2de61ae 253 Pfam PF08220 DeoR-like helix-turn-helix domain 6 58 2.2E-15 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMALA_RS35465 1eca60160c6fa930d9acf418e2de61ae 253 SMART SM01134 73 234 2.7E-54 T 29-03-2018 SMALA_RS35465 1eca60160c6fa930d9acf418e2de61ae 253 Gene3D G3DSA:1.10.10.10 1 58 5.3E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS35465 1eca60160c6fa930d9acf418e2de61ae 253 SUPERFAMILY SSF46785 3 68 6.76E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS35465 1eca60160c6fa930d9acf418e2de61ae 253 SUPERFAMILY SSF100950 74 234 9.94E-25 T 29-03-2018 SMALA_RS35465 1eca60160c6fa930d9acf418e2de61ae 253 Gene3D G3DSA:3.40.50.1360 73 238 1.5E-32 T 29-03-2018 SMALA_RS35465 1eca60160c6fa930d9acf418e2de61ae 253 SMART SM00420 6 58 6.9E-13 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMALA_RS35465 1eca60160c6fa930d9acf418e2de61ae 253 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 3.5E-9 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMALA_RS35465 1eca60160c6fa930d9acf418e2de61ae 253 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 3.5E-9 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMALA_RS10720 4727d8a0ded84ee51bc5b0a300e56e31 316 SMART SM00729 72 278 3.5E-14 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 SMALA_RS10720 4727d8a0ded84ee51bc5b0a300e56e31 316 Gene3D G3DSA:3.20.20.70 22 303 1.5E-24 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS10720 4727d8a0ded84ee51bc5b0a300e56e31 316 Hamap MF_00206 Lipoyl synthase [lipA]. 1 308 138.612 T 29-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 SMALA_RS10720 4727d8a0ded84ee51bc5b0a300e56e31 316 TIGRFAM TIGR00510 lipA: lipoyl synthase 18 307 5.2E-100 T 29-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 SMALA_RS10720 4727d8a0ded84ee51bc5b0a300e56e31 316 PIRSF PIRSF005963 3 316 1.0E-122 T 29-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 SMALA_RS10720 4727d8a0ded84ee51bc5b0a300e56e31 316 SUPERFAMILY SSF102114 36 308 5.23E-62 T 29-03-2018 SMALA_RS10720 4727d8a0ded84ee51bc5b0a300e56e31 316 Pfam PF04055 Radical SAM superfamily 82 236 1.3E-11 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 SMALA_RS29230 3752044017b1acc5de1415f061970d57 870 SMART SM00388 624 692 1.2E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS29230 3752044017b1acc5de1415f061970d57 870 Pfam PF13493 Domain of unknown function (DUF4118) 384 494 1.9E-25 T 29-03-2018 IPR025201 Sensor protein KdpD, transmembrane domain SMALA_RS29230 3752044017b1acc5de1415f061970d57 870 Pfam PF00582 Universal stress protein family 232 334 6.4E-5 T 29-03-2018 IPR006016 UspA GO:0006950 SMALA_RS29230 3752044017b1acc5de1415f061970d57 870 Pfam PF02702 Osmosensitive K+ channel His kinase sensor domain 3 211 4.3E-100 T 29-03-2018 IPR003852 Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal GO:0000155|GO:0000160|GO:0004673|GO:0016020 SMALA_RS29230 3752044017b1acc5de1415f061970d57 870 SUPERFAMILY SSF55874 682 839 1.07E-35 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS29230 3752044017b1acc5de1415f061970d57 870 Gene3D G3DSA:3.40.50.620 208 360 5.9E-12 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS29230 3752044017b1acc5de1415f061970d57 870 Gene3D G3DSA:3.30.565.10 698 845 1.3E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS29230 3752044017b1acc5de1415f061970d57 870 Gene3D G3DSA:1.10.287.130 616 688 1.0E-16 T 29-03-2018 SMALA_RS29230 3752044017b1acc5de1415f061970d57 870 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 733 839 1.5E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS29230 3752044017b1acc5de1415f061970d57 870 Gene3D G3DSA:1.20.120.620 382 487 2.7E-25 T 29-03-2018 SMALA_RS29230 3752044017b1acc5de1415f061970d57 870 Gene3D G3DSA:3.30.450.40 490 578 0.0023 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS29230 3752044017b1acc5de1415f061970d57 870 SMART SM00387 732 842 5.9E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS29230 3752044017b1acc5de1415f061970d57 870 Gene3D G3DSA:3.30.450.40 579 615 0.0095 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS29230 3752044017b1acc5de1415f061970d57 870 Gene3D G3DSA:3.40.50.300 2 128 2.7E-22 T 29-03-2018 SMALA_RS29230 3752044017b1acc5de1415f061970d57 870 Pfam PF00512 His Kinase A (phospho-acceptor) domain 625 692 3.4E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS29230 3752044017b1acc5de1415f061970d57 870 SUPERFAMILY SSF52402 231 346 4.07E-8 T 29-03-2018 SMALA_RS29230 3752044017b1acc5de1415f061970d57 870 PRINTS PR00344 Bacterial sensor protein C-terminal signature 787 797 4.2E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS29230 3752044017b1acc5de1415f061970d57 870 PRINTS PR00344 Bacterial sensor protein C-terminal signature 826 839 4.2E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS29230 3752044017b1acc5de1415f061970d57 870 PRINTS PR00344 Bacterial sensor protein C-terminal signature 769 783 4.2E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS29230 3752044017b1acc5de1415f061970d57 870 PRINTS PR00344 Bacterial sensor protein C-terminal signature 802 820 4.2E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS29230 3752044017b1acc5de1415f061970d57 870 SUPERFAMILY SSF47384 615 692 9.22E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS08035 4c04e961e7e3c4c49b04adb2fc35a4f5 313 SMART SM00342 224 307 1.9E-27 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS08035 4c04e961e7e3c4c49b04adb2fc35a4f5 313 SUPERFAMILY SSF46689 260 308 6.27E-9 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS08035 4c04e961e7e3c4c49b04adb2fc35a4f5 313 Gene3D G3DSA:2.60.120.10 2 128 3.1E-5 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SMALA_RS08035 4c04e961e7e3c4c49b04adb2fc35a4f5 313 Pfam PF12833 Helix-turn-helix domain 230 307 1.6E-17 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS08035 4c04e961e7e3c4c49b04adb2fc35a4f5 313 Gene3D G3DSA:1.10.10.60 206 261 2.7E-10 T 29-03-2018 SMALA_RS08035 4c04e961e7e3c4c49b04adb2fc35a4f5 313 Pfam PF12852 Cupin 2 192 8.6E-52 T 29-03-2018 IPR032783 AraC-type transcription regulator, ligand-binding domain SMALA_RS08035 4c04e961e7e3c4c49b04adb2fc35a4f5 313 Gene3D G3DSA:1.10.10.60 262 309 3.0E-11 T 29-03-2018 SMALA_RS08035 4c04e961e7e3c4c49b04adb2fc35a4f5 313 SUPERFAMILY SSF46689 207 258 3.14E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS08035 4c04e961e7e3c4c49b04adb2fc35a4f5 313 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 261 303 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 SMALA_RS15040 139d4851f1cabdb7018eab4067954925 316 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 9 286 1.8E-69 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMALA_RS15040 139d4851f1cabdb7018eab4067954925 316 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 32 50 - T 29-03-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 SMALA_RS15040 139d4851f1cabdb7018eab4067954925 316 SUPERFAMILY SSF53686 5 295 4.45E-87 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMALA_RS15040 139d4851f1cabdb7018eab4067954925 316 TIGRFAM TIGR01136 cysKM: cysteine synthase 9 298 7.7E-112 T 29-03-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 SMALA_RS15040 139d4851f1cabdb7018eab4067954925 316 Gene3D G3DSA:3.40.50.1100 22 134 7.5E-36 T 29-03-2018 SMALA_RS15040 139d4851f1cabdb7018eab4067954925 316 Gene3D G3DSA:3.40.50.1100 135 309 3.7E-42 T 29-03-2018 SMALA_RS24855 f56b503f444af6c006194e421d794e98 816 SUPERFAMILY SSF53448 452 693 1.0E-61 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS24855 f56b503f444af6c006194e421d794e98 816 Pfam PF01522 Polysaccharide deacetylase 186 290 2.0E-29 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 SMALA_RS24855 f56b503f444af6c006194e421d794e98 816 Gene3D G3DSA:3.20.20.370 174 391 1.9E-48 T 29-03-2018 SMALA_RS24855 f56b503f444af6c006194e421d794e98 816 Gene3D G3DSA:3.90.550.10 434 692 5.9E-66 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS24855 f56b503f444af6c006194e421d794e98 816 SUPERFAMILY SSF88713 184 383 4.2E-52 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 SMALA_RS24855 f56b503f444af6c006194e421d794e98 816 Pfam PF13641 Glycosyltransferase like family 2 458 676 1.2E-38 T 29-03-2018 SMALA_RS10840 f83fda24e38471432e67213fb5690003 1044 Gene3D G3DSA:3.20.20.80 138 463 2.5E-105 T 29-03-2018 SMALA_RS10840 f83fda24e38471432e67213fb5690003 1044 Pfam PF12971 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain 48 128 2.7E-23 T 29-03-2018 IPR024240 Alpha-N-acetylglucosaminidase, N-terminal KEGG: 00531+3.2.1.50|Reactome: R-HSA-2024096 SMALA_RS10840 f83fda24e38471432e67213fb5690003 1044 Pfam PF05089 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain 142 461 2.1E-99 T 29-03-2018 IPR024733 Alpha-N-acetylglucosaminidase, tim-barrel domain KEGG: 00531+3.2.1.50|Reactome: R-HSA-2024096 SMALA_RS10840 f83fda24e38471432e67213fb5690003 1044 Gene3D G3DSA:3.30.379.10 31 137 1.9E-29 T 29-03-2018 SMALA_RS10840 f83fda24e38471432e67213fb5690003 1044 Pfam PF12972 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain 470 734 1.0E-67 T 29-03-2018 IPR024732 Alpha-N-acetylglucosaminidase, C-terminal KEGG: 00531+3.2.1.50|Reactome: R-HSA-2024096 SMALA_RS10840 f83fda24e38471432e67213fb5690003 1044 Gene3D G3DSA:1.20.120.670 464 748 2.0E-72 T 29-03-2018 SMALA_RS16755 372cabe50f61ec3672c3738f7649640c 350 Pfam PF04542 Sigma-70 region 2 16 83 4.0E-15 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS16755 372cabe50f61ec3672c3738f7649640c 350 SUPERFAMILY SSF88659 88 174 1.42E-15 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS16755 372cabe50f61ec3672c3738f7649640c 350 Gene3D G3DSA:1.10.1740.10 1 82 6.5E-21 T 29-03-2018 SMALA_RS16755 372cabe50f61ec3672c3738f7649640c 350 Gene3D G3DSA:1.10.10.10 83 177 1.7E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS16755 372cabe50f61ec3672c3738f7649640c 350 SUPERFAMILY SSF88946 2 91 4.71E-22 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS16755 372cabe50f61ec3672c3738f7649640c 350 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 11 173 6.3E-28 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS16755 372cabe50f61ec3672c3738f7649640c 350 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 37 68 - T 29-03-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS16755 372cabe50f61ec3672c3738f7649640c 350 Pfam PF08281 Sigma-70, region 4 118 170 2.3E-16 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 SUPERFAMILY SSF52777 1746 1988 7.45E-57 T 29-03-2018 SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 SUPERFAMILY SSF47336 2547 2619 9.16E-19 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 ProSitePatterns PS00455 Putative AMP-binding domain signature. 649 660 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 Gene3D G3DSA:2.30.38.10 817 898 3.2E-22 T 29-03-2018 SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 Gene3D G3DSA:2.30.38.10 2354 2435 3.9E-24 T 29-03-2018 SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 Gene3D G3DSA:2.30.38.10 3414 3495 4.6E-23 T 29-03-2018 SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 Gene3D G3DSA:2.30.38.10 5956 6037 2.0E-25 T 29-03-2018 SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 Gene3D G3DSA:3.30.559.10 6229 6430 7.3E-36 T 29-03-2018 SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 Gene3D G3DSA:3.30.559.10 3680 3876 5.7E-34 T 29-03-2018 SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 Gene3D G3DSA:3.30.559.10 2634 2828 6.2E-46 T 29-03-2018 SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 ProSitePatterns PS00012 Phosphopantetheine attachment site. 5140 5155 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 SUPERFAMILY SSF52777 6235 6439 1.56E-40 T 29-03-2018 SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 SUPERFAMILY SSF47336 6154 6223 3.4E-19 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 SUPERFAMILY SSF47336 1010 1081 6.41E-18 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 Gene3D G3DSA:1.10.1200.10 5121 5171 1.5E-22 T 29-03-2018 SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 Gene3D G3DSA:1.10.1200.10 1023 1087 9.6E-24 T 29-03-2018 SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 Gene3D G3DSA:1.10.1200.10 6167 6228 4.1E-23 T 29-03-2018 SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 Gene3D G3DSA:1.10.1200.10 3615 3679 9.3E-21 T 29-03-2018 SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1041 1056 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 ProSitePatterns PS00455 Putative AMP-binding domain signature. 4754 4765 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 Gene3D G3DSA:3.40.50.980 4622 4759 5.5E-39 T 29-03-2018 SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 Gene3D G3DSA:3.40.50.980 511 654 1.7E-40 T 29-03-2018 SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 Gene3D G3DSA:3.40.50.980 3102 3247 5.4E-38 T 29-03-2018 SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 Gene3D G3DSA:3.40.50.980 5658 5795 4.5E-40 T 29-03-2018 SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 SUPERFAMILY SSF56801 5625 6174 1.01E-158 T 29-03-2018 SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 Pfam PF00550 Phosphopantetheine attachment site 2556 2619 6.8E-15 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 Pfam PF00550 Phosphopantetheine attachment site 1019 1081 1.1E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 Pfam PF00550 Phosphopantetheine attachment site 6163 6222 1.2E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 Pfam PF00550 Phosphopantetheine attachment site 5118 5181 1.0E-15 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 Pfam PF00550 Phosphopantetheine attachment site 3612 3669 6.5E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 SUPERFAMILY SSF47336 5108 5216 1.26E-21 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 SUPERFAMILY SSF52777 3687 3866 3.67E-40 T 29-03-2018 SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 SUPERFAMILY SSF52777 241 491 3.78E-55 T 29-03-2018 SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 SUPERFAMILY SSF52777 6428 6681 9.23E-39 T 29-03-2018 SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 5688 6068 1.5E-126 T 29-03-2018 IPR010071 Amino acid adenylation domain SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 542 929 8.8E-116 T 29-03-2018 IPR010071 Amino acid adenylation domain SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 4652 5031 2.4E-119 T 29-03-2018 IPR010071 Amino acid adenylation domain SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 3134 3526 2.8E-109 T 29-03-2018 IPR010071 Amino acid adenylation domain SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2046 2466 4.7E-135 T 29-03-2018 IPR010071 Amino acid adenylation domain SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 SUPERFAMILY SSF56801 3070 3622 1.44E-143 T 29-03-2018 SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 SUPERFAMILY SSF56801 1983 2567 1.31E-160 T 29-03-2018 SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 Gene3D G3DSA:3.30.300.30 3497 3614 5.3E-41 T 29-03-2018 SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 Gene3D G3DSA:3.30.300.30 900 1022 4.1E-43 T 29-03-2018 SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 Gene3D G3DSA:3.30.300.30 2437 2559 2.3E-44 T 29-03-2018 SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 Gene3D G3DSA:3.30.300.30 6039 6166 8.7E-42 T 29-03-2018 SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 Gene3D G3DSA:3.30.300.30 5002 5120 2.0E-44 T 29-03-2018 SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 SUPERFAMILY SSF52777 38 253 7.23E-50 T 29-03-2018 SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 Gene3D G3DSA:3.40.50.980 4760 4915 4.3E-28 T 29-03-2018 SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 Gene3D G3DSA:3.40.50.980 3248 3405 3.4E-30 T 29-03-2018 SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 Gene3D G3DSA:3.40.50.980 655 813 1.2E-31 T 29-03-2018 SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 Pfam PF00668 Condensation domain 5202 5643 7.1E-104 T 29-03-2018 IPR001242 Condensation domain SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 Pfam PF00668 Condensation domain 1562 2002 4.6E-84 T 29-03-2018 IPR001242 Condensation domain SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 Pfam PF00668 Condensation domain 6239 6682 6.3E-72 T 29-03-2018 IPR001242 Condensation domain SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 Pfam PF00668 Condensation domain 2646 3090 4.4E-102 T 29-03-2018 IPR001242 Condensation domain SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 Pfam PF00668 Condensation domain 3690 4136 2.7E-66 T 29-03-2018 IPR001242 Condensation domain SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 Pfam PF00668 Condensation domain 4165 4608 6.1E-83 T 29-03-2018 IPR001242 Condensation domain SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 Pfam PF00668 Condensation domain 1099 1539 3.7E-66 T 29-03-2018 IPR001242 Condensation domain SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 Pfam PF00668 Condensation domain 43 499 9.4E-96 T 29-03-2018 IPR001242 Condensation domain SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 Gene3D G3DSA:3.30.559.10 1088 1295 6.0E-34 T 29-03-2018 SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 Gene3D G3DSA:3.30.559.10 4075 4370 5.1E-38 T 29-03-2018 SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 Gene3D G3DSA:3.30.559.10 1536 1762 1.7E-36 T 29-03-2018 SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 Gene3D G3DSA:3.30.559.10 5172 5406 1.4E-50 T 29-03-2018 SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 Gene3D G3DSA:3.30.559.10 30 254 2.6E-50 T 29-03-2018 SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 Gene3D G3DSA:3.40.50.980 5796 5945 2.1E-38 T 29-03-2018 SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 Gene3D G3DSA:3.40.50.980 2179 2339 3.0E-43 T 29-03-2018 SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 SUPERFAMILY SSF52777 1560 1760 1.67E-40 T 29-03-2018 SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 ProSitePatterns PS00455 Putative AMP-binding domain signature. 3242 3253 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 SUPERFAMILY SSF56801 479 1029 9.94E-145 T 29-03-2018 SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3633 3648 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 ProSitePatterns PS00012 Phosphopantetheine attachment site. 6185 6200 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 SUPERFAMILY SSF52777 5206 5383 1.89E-51 T 29-03-2018 SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 SUPERFAMILY SSF52777 5389 5654 1.89E-62 T 29-03-2018 SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 1401 1554 5.9E-34 T 29-03-2018 IPR010060 Non-ribosomal peptide synthase SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 4000 4157 1.9E-36 T 29-03-2018 IPR010060 Non-ribosomal peptide synthase SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 SUPERFAMILY SSF56801 4592 5129 1.19E-151 T 29-03-2018 SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 SUPERFAMILY SSF52777 4164 4366 7.11E-39 T 29-03-2018 SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 SUPERFAMILY SSF47336 3601 3669 1.7E-18 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 SMART SM00823 Phosphopantetheine attachment site 1017 1085 6.5E-5 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 SMART SM00823 Phosphopantetheine attachment site 2554 2623 1.5E-7 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 SMART SM00823 Phosphopantetheine attachment site 5116 5185 3.5E-12 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 SMART SM00823 Phosphopantetheine attachment site 3609 3677 0.0021 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 SMART SM00823 Phosphopantetheine attachment site 6161 6229 8.6E-5 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 SUPERFAMILY SSF52777 3878 4134 1.02E-46 T 29-03-2018 SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 Pfam PF00501 AMP-binding enzyme 5667 6044 1.2E-90 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 Pfam PF00501 AMP-binding enzyme 3111 3502 3.5E-84 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 Pfam PF00501 AMP-binding enzyme 519 905 8.6E-85 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 Pfam PF00501 AMP-binding enzyme 2025 2442 2.5E-98 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 Pfam PF00501 AMP-binding enzyme 4630 5007 2.3E-84 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 SUPERFAMILY SSF52777 1282 1530 2.45E-43 T 29-03-2018 SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 SUPERFAMILY SSF52777 4352 4615 1.11E-56 T 29-03-2018 SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 SUPERFAMILY SSF52777 2836 3098 2.0E-63 T 29-03-2018 SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 Gene3D G3DSA:3.40.50.980 2018 2178 2.4E-44 T 29-03-2018 SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 Gene3D G3DSA:1.10.1200.10 2560 2626 9.6E-24 T 29-03-2018 SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 Pfam PF13193 AMP-binding enzyme C-terminal domain 3510 3582 5.8E-15 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 Pfam PF13193 AMP-binding enzyme C-terminal domain 5015 5090 7.7E-14 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 Pfam PF13193 AMP-binding enzyme C-terminal domain 2450 2526 3.0E-13 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 Pfam PF13193 AMP-binding enzyme C-terminal domain 6052 6133 3.4E-11 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 Pfam PF13193 AMP-binding enzyme C-terminal domain 913 989 5.1E-14 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 SUPERFAMILY SSF52777 2643 2848 2.89E-50 T 29-03-2018 SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 SUPERFAMILY SSF52777 1094 1269 1.19E-40 T 29-03-2018 SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 ProSitePatterns PS00455 Putative AMP-binding domain signature. 5792 5803 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 Gene3D G3DSA:2.30.38.10 4916 4997 1.5E-24 T 29-03-2018 SMALA_RS01360 d745dd24ce6db1241f9189d04afc73db 6685 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2578 2593 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS00625 b6a16d847c7334a0cd09c5761e0d9c1b 319 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 26 306 3.6E-27 T 29-03-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD SMALA_RS20780 60f70152d694eb6b3c4309305b3cc51a 498 SUPERFAMILY SSF55874 311 428 9.87E-10 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS20780 60f70152d694eb6b3c4309305b3cc51a 498 Pfam PF07730 Histidine kinase 224 288 4.8E-19 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMALA_RS20780 60f70152d694eb6b3c4309305b3cc51a 498 Gene3D G3DSA:3.30.565.10 302 437 3.1E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS05525 d7078efad93463e62c68834b26eaf1c2 1179 Gene3D G3DSA:3.40.920.10 723 926 4.9E-47 T 29-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 SMALA_RS05525 d7078efad93463e62c68834b26eaf1c2 1179 Gene3D G3DSA:3.40.50.970 23 266 1.2E-20 T 29-03-2018 SMALA_RS05525 d7078efad93463e62c68834b26eaf1c2 1179 SUPERFAMILY SSF53323 726 926 1.44E-20 T 29-03-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 SMALA_RS05525 d7078efad93463e62c68834b26eaf1c2 1179 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 734 920 1.4E-24 T 29-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 SMALA_RS05525 d7078efad93463e62c68834b26eaf1c2 1179 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 457 545 4.0E-7 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 SMALA_RS05525 d7078efad93463e62c68834b26eaf1c2 1179 SUPERFAMILY SSF52518 437 620 8.03E-15 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold SMALA_RS05525 d7078efad93463e62c68834b26eaf1c2 1179 Gene3D G3DSA:3.40.50.970 267 647 9.3E-32 T 29-03-2018 SMALA_RS05525 d7078efad93463e62c68834b26eaf1c2 1179 SUPERFAMILY SSF52518 27 205 8.83E-10 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold SMALA_RS03450 b06363a011210a92a8d5be6419833d6f 356 SUPERFAMILY SSF52540 18 255 1.82E-84 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS03450 b06363a011210a92a8d5be6419833d6f 356 SUPERFAMILY SSF50331 259 350 2.38E-7 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal SMALA_RS03450 b06363a011210a92a8d5be6419833d6f 356 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS03450 b06363a011210a92a8d5be6419833d6f 356 Gene3D G3DSA:3.40.50.300 13 255 1.6E-74 T 29-03-2018 SMALA_RS03450 b06363a011210a92a8d5be6419833d6f 356 Pfam PF08402 TOBE domain 270 352 4.3E-13 T 29-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 SMALA_RS03450 b06363a011210a92a8d5be6419833d6f 356 Pfam PF00005 ABC transporter 34 175 9.3E-34 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS03450 b06363a011210a92a8d5be6419833d6f 356 SMART SM00382 42 225 3.3E-18 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS22400 105dfe61e0a0886719f08b112b3c21cd 351 SUPERFAMILY SSF56176 8 183 9.81E-35 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SMALA_RS22400 105dfe61e0a0886719f08b112b3c21cd 351 SUPERFAMILY SSF56194 213 349 6.02E-32 T 29-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMALA_RS22400 105dfe61e0a0886719f08b112b3c21cd 351 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 351 75.524 T 29-03-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMALA_RS22400 105dfe61e0a0886719f08b112b3c21cd 351 Pfam PF01565 FAD binding domain 23 138 2.7E-20 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 SMALA_RS22400 105dfe61e0a0886719f08b112b3c21cd 351 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 213 347 2.0E-36 T 29-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMALA_RS22400 105dfe61e0a0886719f08b112b3c21cd 351 Gene3D G3DSA:3.30.43.10 1 71 1.0E-24 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 SMALA_RS22400 105dfe61e0a0886719f08b112b3c21cd 351 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 9 343 4.2E-46 T 29-03-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMALA_RS22400 105dfe61e0a0886719f08b112b3c21cd 351 Gene3D G3DSA:3.90.78.10 229 347 8.7E-40 T 29-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMALA_RS22400 105dfe61e0a0886719f08b112b3c21cd 351 Gene3D G3DSA:3.30.465.10 72 224 3.5E-44 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SMALA_RS12940 146de5511cb4b0a97f83fa2da5104bfe 247 SUPERFAMILY SSF88697 5 72 5.22E-10 T 29-03-2018 IPR015947 PUA-like domain SMALA_RS12940 146de5511cb4b0a97f83fa2da5104bfe 247 Pfam PF04452 RNA methyltransferase 21 239 3.0E-61 T 29-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SMALA_RS12940 146de5511cb4b0a97f83fa2da5104bfe 247 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 20 239 7.0E-33 T 29-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SMALA_RS12940 146de5511cb4b0a97f83fa2da5104bfe 247 Gene3D G3DSA:3.40.1280.10 76 247 5.8E-52 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal SMALA_RS12940 146de5511cb4b0a97f83fa2da5104bfe 247 SUPERFAMILY SSF75217 78 247 7.85E-45 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases SMALA_RS12940 146de5511cb4b0a97f83fa2da5104bfe 247 Gene3D G3DSA:2.40.240.20 1 74 3.1E-19 T 29-03-2018 SMALA_RS12940 146de5511cb4b0a97f83fa2da5104bfe 247 PIRSF PIRSF015601 5 246 3.7E-45 T 29-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SMALA_RS02735 bdbf9965f9fbbdc902f7825e13bad570 216 Gene3D G3DSA:1.10.10.10 137 214 3.2E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS02735 bdbf9965f9fbbdc902f7825e13bad570 216 Gene3D G3DSA:3.40.50.2300 2 136 2.1E-34 T 29-03-2018 SMALA_RS02735 bdbf9965f9fbbdc902f7825e13bad570 216 SUPERFAMILY SSF46894 144 213 2.48E-20 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS02735 bdbf9965f9fbbdc902f7825e13bad570 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 5.8E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS02735 bdbf9965f9fbbdc902f7825e13bad570 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 5.8E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS02735 bdbf9965f9fbbdc902f7825e13bad570 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 5.8E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS02735 bdbf9965f9fbbdc902f7825e13bad570 216 SMART SM00448 3 118 9.7E-28 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS02735 bdbf9965f9fbbdc902f7825e13bad570 216 Pfam PF00072 Response regulator receiver domain 5 119 5.7E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS02735 bdbf9965f9fbbdc902f7825e13bad570 216 SMART SM00421 152 209 7.8E-25 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS02735 bdbf9965f9fbbdc902f7825e13bad570 216 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 209 6.7E-18 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS02735 bdbf9965f9fbbdc902f7825e13bad570 216 ProSitePatterns PS00622 LuxR-type HTH domain signature. 169 196 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS02735 bdbf9965f9fbbdc902f7825e13bad570 216 SUPERFAMILY SSF52172 1 135 1.35E-30 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS18380 bbc4ab47cb47ddc64c175055975fcaee 396 Gene3D G3DSA:3.40.350.10 13 160 1.7E-15 T 29-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal SMALA_RS18380 bbc4ab47cb47ddc64c175055975fcaee 396 SUPERFAMILY SSF53092 24 162 1.92E-17 T 29-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal SMALA_RS18380 bbc4ab47cb47ddc64c175055975fcaee 396 Pfam PF00557 Metallopeptidase family M24 171 358 1.3E-29 T 29-03-2018 IPR000994 Peptidase M24 SMALA_RS18380 bbc4ab47cb47ddc64c175055975fcaee 396 SUPERFAMILY SSF55920 162 388 7.72E-48 T 29-03-2018 IPR000994 Peptidase M24 SMALA_RS18380 bbc4ab47cb47ddc64c175055975fcaee 396 Pfam PF01321 Creatinase/Prolidase N-terminal domain 29 163 1.9E-11 T 29-03-2018 IPR000587 Creatinase, N-terminal GO:0016787 SMALA_RS18380 bbc4ab47cb47ddc64c175055975fcaee 396 Gene3D G3DSA:3.90.230.10 162 389 4.7E-41 T 29-03-2018 SMALA_RS05185 e27e0f196d44d1507755a910fa56e0fd 514 Gene3D G3DSA:3.40.50.300 1 233 5.7E-52 T 29-03-2018 SMALA_RS05185 e27e0f196d44d1507755a910fa56e0fd 514 ProSitePatterns PS00211 ABC transporters family signature. 401 415 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS05185 e27e0f196d44d1507755a910fa56e0fd 514 SUPERFAMILY SSF52540 4 226 4.0E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS05185 e27e0f196d44d1507755a910fa56e0fd 514 Gene3D G3DSA:3.40.50.300 241 503 5.7E-40 T 29-03-2018 SMALA_RS05185 e27e0f196d44d1507755a910fa56e0fd 514 SUPERFAMILY SSF52540 261 481 8.94E-47 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS05185 e27e0f196d44d1507755a910fa56e0fd 514 SMART SM00382 30 218 6.3E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS05185 e27e0f196d44d1507755a910fa56e0fd 514 SMART SM00382 281 477 3.4E-5 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS05185 e27e0f196d44d1507755a910fa56e0fd 514 Pfam PF00005 ABC transporter 273 428 6.5E-21 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS05185 e27e0f196d44d1507755a910fa56e0fd 514 Pfam PF00005 ABC transporter 21 170 1.3E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS06775 d9ab3d851d5ef1d38bede405efebc6cf 209 Gene3D G3DSA:3.40.50.720 2 186 6.0E-30 T 29-03-2018 SMALA_RS06775 d9ab3d851d5ef1d38bede405efebc6cf 209 SUPERFAMILY SSF51735 4 191 6.27E-40 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS06775 d9ab3d851d5ef1d38bede405efebc6cf 209 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 4 92 1.4E-16 T 29-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal SMALA_RS12735 0f2354d6b28fe32b262de546af1be783 300 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 183 200 2.5E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS12735 0f2354d6b28fe32b262de546af1be783 300 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 2.5E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS12735 0f2354d6b28fe32b262de546af1be783 300 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 2.5E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS12735 0f2354d6b28fe32b262de546af1be783 300 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 2.5E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS12735 0f2354d6b28fe32b262de546af1be783 300 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 181 2.5E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS12735 0f2354d6b28fe32b262de546af1be783 300 Pfam PF00106 short chain dehydrogenase 4 202 3.2E-26 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS12735 0f2354d6b28fe32b262de546af1be783 300 Gene3D G3DSA:3.40.50.720 1 289 8.1E-46 T 29-03-2018 SMALA_RS12735 0f2354d6b28fe32b262de546af1be783 300 SUPERFAMILY SSF51735 1 248 2.91E-45 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS01585 c8cc4e8329ad1a5f28920cfb0ecd8a8a 282 SUPERFAMILY SSF53335 12 279 1.25E-56 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS01585 c8cc4e8329ad1a5f28920cfb0ecd8a8a 282 Gene3D G3DSA:3.40.50.150 31 279 8.4E-53 T 29-03-2018 SMALA_RS01585 c8cc4e8329ad1a5f28920cfb0ecd8a8a 282 Pfam PF08241 Methyltransferase domain 71 168 6.5E-24 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 SMALA_RS24405 a53006b32d515c6f860236752549943e 290 Pfam PF02585 GlcNAc-PI de-N-acetylase 8 154 9.6E-26 T 29-03-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 SMALA_RS24405 a53006b32d515c6f860236752549943e 290 Gene3D G3DSA:3.40.50.10320 1 290 3.1E-73 T 29-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 SMALA_RS24405 a53006b32d515c6f860236752549943e 290 TIGRFAM TIGR03446 mycothiol_Mca: mycothiol conjugate amidase Mca 5 287 1.1E-149 T 29-03-2018 IPR017811 Mycothiol S-conjugate amidase Mca GO:0010126 KEGG: 00311+3.5.1.11 SMALA_RS24405 a53006b32d515c6f860236752549943e 290 SUPERFAMILY SSF102588 4 288 1.96E-74 T 29-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 SMALA_RS24405 a53006b32d515c6f860236752549943e 290 Hamap MF_01482 Mycothiol S-conjugate amidase [mca]. 8 288 52.172 T 29-03-2018 IPR017811 Mycothiol S-conjugate amidase Mca GO:0010126 KEGG: 00311+3.5.1.11 SMALA_RS13175 9c11019f7be6b13a3dafdf8134f1a132 339 Gene3D G3DSA:3.30.420.40 154 189 2.5E-4 T 29-03-2018 SMALA_RS13175 9c11019f7be6b13a3dafdf8134f1a132 339 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 6 330 1.1E-153 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 SMALA_RS13175 9c11019f7be6b13a3dafdf8134f1a132 339 Pfam PF06723 MreB/Mbl protein 6 330 4.3E-156 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 SMALA_RS13175 9c11019f7be6b13a3dafdf8134f1a132 339 SUPERFAMILY SSF53067 144 322 3.27E-51 T 29-03-2018 SMALA_RS13175 9c11019f7be6b13a3dafdf8134f1a132 339 SUPERFAMILY SSF53067 5 142 1.58E-42 T 29-03-2018 SMALA_RS13175 9c11019f7be6b13a3dafdf8134f1a132 339 Gene3D G3DSA:3.30.420.40 3 153 1.4E-42 T 29-03-2018 SMALA_RS13175 9c11019f7be6b13a3dafdf8134f1a132 339 Gene3D G3DSA:3.90.640.10 190 245 5.0E-32 T 29-03-2018 SMALA_RS13175 9c11019f7be6b13a3dafdf8134f1a132 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 43 61 4.4E-62 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 SMALA_RS13175 9c11019f7be6b13a3dafdf8134f1a132 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 294 320 4.4E-62 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 SMALA_RS13175 9c11019f7be6b13a3dafdf8134f1a132 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 181 201 4.4E-62 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 SMALA_RS13175 9c11019f7be6b13a3dafdf8134f1a132 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 63 86 4.4E-62 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 SMALA_RS13175 9c11019f7be6b13a3dafdf8134f1a132 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 126 145 4.4E-62 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 SMALA_RS13175 9c11019f7be6b13a3dafdf8134f1a132 339 Gene3D G3DSA:3.30.420.40 246 311 7.7E-12 T 29-03-2018 SMALA_RS16190 c0e6ca5d7102c4c6c64a891a80801e02 459 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 333 1.9E-44 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS16190 c0e6ca5d7102c4c6c64a891a80801e02 459 Gene3D G3DSA:3.50.50.60 2 138 6.6E-16 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS16190 c0e6ca5d7102c4c6c64a891a80801e02 459 Gene3D G3DSA:3.40.50.720 160 382 1.4E-26 T 29-03-2018 SMALA_RS16190 c0e6ca5d7102c4c6c64a891a80801e02 459 SUPERFAMILY SSF51905 143 351 9.91E-12 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS16190 c0e6ca5d7102c4c6c64a891a80801e02 459 SUPERFAMILY SSF51905 5 175 3.82E-26 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS16190 c0e6ca5d7102c4c6c64a891a80801e02 459 SUPERFAMILY SSF51905 263 343 3.82E-26 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS16190 c0e6ca5d7102c4c6c64a891a80801e02 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 5.8E-7 T 29-03-2018 SMALA_RS16190 c0e6ca5d7102c4c6c64a891a80801e02 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 166 184 5.8E-7 T 29-03-2018 SMALA_RS16190 c0e6ca5d7102c4c6c64a891a80801e02 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 106 124 5.8E-7 T 29-03-2018 SMALA_RS35835 268844fc7d3de40b34dac65cf96d957a 409 Gene3D G3DSA:1.10.630.10 3 409 3.2E-79 T 29-03-2018 SMALA_RS35835 268844fc7d3de40b34dac65cf96d957a 409 Pfam PF00067 Cytochrome P450 281 379 4.5E-17 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS35835 268844fc7d3de40b34dac65cf96d957a 409 SUPERFAMILY SSF48264 22 409 9.95E-99 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS35835 268844fc7d3de40b34dac65cf96d957a 409 PRINTS PR00359 B-class P450 signature 141 157 5.7E-53 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS35835 268844fc7d3de40b34dac65cf96d957a 409 PRINTS PR00359 B-class P450 signature 158 173 5.7E-53 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS35835 268844fc7d3de40b34dac65cf96d957a 409 PRINTS PR00359 B-class P450 signature 95 106 5.7E-53 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS35835 268844fc7d3de40b34dac65cf96d957a 409 PRINTS PR00359 B-class P450 signature 358 369 5.7E-53 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS35835 268844fc7d3de40b34dac65cf96d957a 409 PRINTS PR00359 B-class P450 signature 282 293 5.7E-53 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS35835 268844fc7d3de40b34dac65cf96d957a 409 PRINTS PR00359 B-class P450 signature 328 343 5.7E-53 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS35835 268844fc7d3de40b34dac65cf96d957a 409 PRINTS PR00359 B-class P450 signature 196 218 5.7E-53 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS35835 268844fc7d3de40b34dac65cf96d957a 409 PRINTS PR00359 B-class P450 signature 300 327 5.7E-53 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS35835 268844fc7d3de40b34dac65cf96d957a 409 PRINTS PR00359 B-class P450 signature 349 358 5.7E-53 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS11660 3aaceea186abbb37cc28db0b1c532ba3 219 Pfam PF07510 Protein of unknown function (DUF1524) 104 211 2.0E-9 T 29-03-2018 IPR011089 Domain of unknown function DUF1524 SMALA_RS31225 4b7f81a2a72cdca986c5ad391b2dfba9 194 Gene3D G3DSA:1.10.10.10 115 192 1.1E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS31225 4b7f81a2a72cdca986c5ad391b2dfba9 194 Gene3D G3DSA:1.10.1740.10 16 100 4.9E-22 T 29-03-2018 SMALA_RS31225 4b7f81a2a72cdca986c5ad391b2dfba9 194 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 31 189 2.8E-25 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS31225 4b7f81a2a72cdca986c5ad391b2dfba9 194 SUPERFAMILY SSF88659 125 190 3.05E-15 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS31225 4b7f81a2a72cdca986c5ad391b2dfba9 194 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 57 89 - T 29-03-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS31225 4b7f81a2a72cdca986c5ad391b2dfba9 194 Pfam PF08281 Sigma-70, region 4 133 186 6.9E-13 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS31225 4b7f81a2a72cdca986c5ad391b2dfba9 194 SUPERFAMILY SSF88946 14 110 7.65E-23 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS31225 4b7f81a2a72cdca986c5ad391b2dfba9 194 Pfam PF04542 Sigma-70 region 2 35 102 4.7E-17 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS24215 32f5717cc230b058b26bff9075ae1fb7 532 Pfam PF13556 PucR C-terminal helix-turn-helix domain 365 420 2.5E-7 T 29-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain SMALA_RS24215 32f5717cc230b058b26bff9075ae1fb7 532 Pfam PF13556 PucR C-terminal helix-turn-helix domain 470 528 3.8E-12 T 29-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain SMALA_RS24215 32f5717cc230b058b26bff9075ae1fb7 532 SUPERFAMILY SSF103196 27 129 9.94E-5 T 29-03-2018 SMALA_RS13880 08cb407e04423a6cfc444dc71639915e 315 Pfam PF00294 pfkB family carbohydrate kinase 9 304 4.9E-54 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB SMALA_RS13880 08cb407e04423a6cfc444dc71639915e 315 TIGRFAM TIGR04382 myo_inos_iolC_N: 5-dehydro-2-deoxygluconokinase 5 312 1.5E-116 T 29-03-2018 IPR030830 5-Dehydro-2-deoxygluconokinase KEGG: 00562+2.7.1.92 SMALA_RS13880 08cb407e04423a6cfc444dc71639915e 315 Gene3D G3DSA:3.40.1190.20 5 315 2.1E-89 T 29-03-2018 IPR029056 Ribokinase-like SMALA_RS13880 08cb407e04423a6cfc444dc71639915e 315 SUPERFAMILY SSF53613 4 312 1.03E-78 T 29-03-2018 IPR029056 Ribokinase-like SMALA_RS43340 e719d6bc5055bd7ea90986168e3bc7fa 417 Gene3D G3DSA:1.25.40.10 181 305 4.8E-4 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS43340 e719d6bc5055bd7ea90986168e3bc7fa 417 Gene3D G3DSA:1.25.40.10 306 373 0.073 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS00805 3f854a5350abe5d59af6e3f2f9c916e5 270 SUPERFAMILY SSF52540 9 237 4.23E-68 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS00805 3f854a5350abe5d59af6e3f2f9c916e5 270 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS00805 3f854a5350abe5d59af6e3f2f9c916e5 270 Pfam PF00005 ABC transporter 30 168 1.3E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS00805 3f854a5350abe5d59af6e3f2f9c916e5 270 SMART SM00382 38 218 2.6E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS00805 3f854a5350abe5d59af6e3f2f9c916e5 270 Gene3D G3DSA:3.40.50.300 4 226 7.4E-65 T 29-03-2018 SMALA_RS13665 13d74a4198a9a365fa128ef6025952d0 312 SUPERFAMILY SSF52151 9 130 4.45E-27 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS13665 13d74a4198a9a365fa128ef6025952d0 312 SUPERFAMILY SSF52151 201 298 4.45E-27 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS13665 13d74a4198a9a365fa128ef6025952d0 312 Gene3D G3DSA:3.40.366.10 3 311 1.2E-25 T 29-03-2018 SMALA_RS40355 37638dac9099bc66fb3bf56522607d50 477 Gene3D G3DSA:3.30.420.40 240 472 9.4E-43 T 29-03-2018 SMALA_RS40355 37638dac9099bc66fb3bf56522607d50 477 SUPERFAMILY SSF53067 4 231 2.49E-27 T 29-03-2018 SMALA_RS40355 37638dac9099bc66fb3bf56522607d50 477 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 5 232 1.3E-20 T 29-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 SMALA_RS40355 37638dac9099bc66fb3bf56522607d50 477 SUPERFAMILY SSF53067 242 468 1.23E-41 T 29-03-2018 SMALA_RS40355 37638dac9099bc66fb3bf56522607d50 477 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 247 421 5.2E-24 T 29-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 SMALA_RS40355 37638dac9099bc66fb3bf56522607d50 477 Gene3D G3DSA:3.30.420.40 1 233 4.0E-34 T 29-03-2018 SMALA_RS40355 37638dac9099bc66fb3bf56522607d50 477 PIRSF PIRSF000538 2 475 1.1E-68 T 29-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 SMALA_RS26455 6ad021dbbf9559e854f74a5291a9675e 163 TIGRFAM TIGR02754 sod_Ni_protease: nickel-type superoxide dismutase maturation protease 27 107 1.0E-20 T 29-03-2018 IPR014124 Peptidase S26A, superoxide dismutase maturation protease, nickel-type SMALA_RS26455 6ad021dbbf9559e854f74a5291a9675e 163 Pfam PF00717 Peptidase S24-like 27 88 5.7E-11 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C SMALA_RS26455 6ad021dbbf9559e854f74a5291a9675e 163 SUPERFAMILY SSF51306 25 119 9.16E-22 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C SMALA_RS26455 6ad021dbbf9559e854f74a5291a9675e 163 Gene3D G3DSA:2.10.109.10 75 128 7.8E-9 T 29-03-2018 SMALA_RS26455 6ad021dbbf9559e854f74a5291a9675e 163 Gene3D G3DSA:2.10.109.10 21 74 2.8E-8 T 29-03-2018 SMALA_RS04325 c080cdad3ec471e098d96cd1f975acbf 283 SUPERFAMILY SSF159713 93 259 8.11E-15 T 29-03-2018 SMALA_RS04325 c080cdad3ec471e098d96cd1f975acbf 283 Gene3D G3DSA:3.40.50.2300 38 265 4.9E-5 T 29-03-2018 SMALA_RS04325 c080cdad3ec471e098d96cd1f975acbf 283 Pfam PF04016 Putative heavy-metal chelation 152 243 2.2E-6 T 29-03-2018 IPR007161 Putative heavy-metal chelation domain SMALA_RS11075 d027d9cc9ccb50112e961c028b05c9a4 179 SUPERFAMILY SSF55729 12 161 2.84E-20 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS11075 d027d9cc9ccb50112e961c028b05c9a4 179 Gene3D G3DSA:3.40.630.30 1 168 1.8E-21 T 29-03-2018 SMALA_RS11075 d027d9cc9ccb50112e961c028b05c9a4 179 Pfam PF13508 Acetyltransferase (GNAT) domain 61 156 7.4E-8 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SMALA_RS33615 7de2b61fe7afc9c5b7f4042a09406cb3 448 ProDom PD011777 SYNTHETASE TRANSFERASE METHIONINE ADENOSYLTRANSFERASE S-ADENOSYLMETHIONINE NUCLEOTIDE-BINDING METABOLISM ATP-BINDING MAGNESIUM ONE-CARBON 65 448 2.0E-55 T 29-03-2018 SMALA_RS33615 7de2b61fe7afc9c5b7f4042a09406cb3 448 Pfam PF01941 S-adenosylmethionine synthetase (AdoMet synthetase) 64 441 2.4E-94 T 29-03-2018 IPR027790 S-adenosylmethionine synthase KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912 SMALA_RS40015 aa436656564c2bc51bfa3b48493910ee 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 64 1.0E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS40015 aa436656564c2bc51bfa3b48493910ee 202 SUPERFAMILY SSF48498 85 200 2.81E-26 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS40015 aa436656564c2bc51bfa3b48493910ee 202 Gene3D G3DSA:1.10.10.60 5 65 2.6E-13 T 29-03-2018 SMALA_RS40015 aa436656564c2bc51bfa3b48493910ee 202 SUPERFAMILY SSF46689 8 83 2.77E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS40015 aa436656564c2bc51bfa3b48493910ee 202 Gene3D G3DSA:1.10.357.10 66 198 1.8E-22 T 29-03-2018 SMALA_RS40015 aa436656564c2bc51bfa3b48493910ee 202 ProSitePatterns PS01081 TetR-type HTH domain signature. 32 62 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site SMALA_RS08020 a844b54dfca5e87d7eca6b09973065b1 710 SUPERFAMILY SSF54665 7 132 5.76E-32 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMALA_RS08020 a844b54dfca5e87d7eca6b09973065b1 710 Gene3D G3DSA:3.30.365.10 166 272 1.9E-33 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMALA_RS08020 a844b54dfca5e87d7eca6b09973065b1 710 Gene3D G3DSA:3.30.365.10 451 539 1.1E-22 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMALA_RS08020 a844b54dfca5e87d7eca6b09973065b1 710 Gene3D G3DSA:3.30.365.10 273 437 3.8E-36 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMALA_RS08020 a844b54dfca5e87d7eca6b09973065b1 710 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 167 651 2.6E-118 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMALA_RS08020 a844b54dfca5e87d7eca6b09973065b1 710 SUPERFAMILY SSF56003 121 709 2.36E-163 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMALA_RS08020 a844b54dfca5e87d7eca6b09973065b1 710 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 25 129 6.5E-20 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMALA_RS08020 a844b54dfca5e87d7eca6b09973065b1 710 Gene3D G3DSA:3.90.1170.50 9 129 1.2E-27 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMALA_RS08020 a844b54dfca5e87d7eca6b09973065b1 710 Gene3D G3DSA:3.30.365.10 540 710 1.6E-47 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMALA_RS08020 a844b54dfca5e87d7eca6b09973065b1 710 SMART SM01008 25 129 1.2E-31 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMALA_RS31740 81caf7dee5f981a344884385e55fe8af 451 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 82 100 - T 29-03-2018 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site SMALA_RS31740 81caf7dee5f981a344884385e55fe8af 451 PRINTS PR01181 Diaminopimelate decarboxylase signature 188 197 1.4E-25 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMALA_RS31740 81caf7dee5f981a344884385e55fe8af 451 PRINTS PR01181 Diaminopimelate decarboxylase signature 100 117 1.4E-25 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMALA_RS31740 81caf7dee5f981a344884385e55fe8af 451 PRINTS PR01181 Diaminopimelate decarboxylase signature 416 438 1.4E-25 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMALA_RS31740 81caf7dee5f981a344884385e55fe8af 451 PRINTS PR01181 Diaminopimelate decarboxylase signature 333 351 1.4E-25 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMALA_RS31740 81caf7dee5f981a344884385e55fe8af 451 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 34 448 1.8E-126 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMALA_RS31740 81caf7dee5f981a344884385e55fe8af 451 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 406 419 1.2E-18 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMALA_RS31740 81caf7dee5f981a344884385e55fe8af 451 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 102 114 1.2E-18 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMALA_RS31740 81caf7dee5f981a344884385e55fe8af 451 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 305 324 1.2E-18 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMALA_RS31740 81caf7dee5f981a344884385e55fe8af 451 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 216 229 1.2E-18 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMALA_RS31740 81caf7dee5f981a344884385e55fe8af 451 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 82 100 1.2E-18 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMALA_RS31740 81caf7dee5f981a344884385e55fe8af 451 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 42 449 38.923 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMALA_RS31740 81caf7dee5f981a344884385e55fe8af 451 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 272 406 2.6E-16 T 29-03-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 SMALA_RS31740 81caf7dee5f981a344884385e55fe8af 451 SUPERFAMILY SSF50621 295 449 2.09E-48 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 SMALA_RS31740 81caf7dee5f981a344884385e55fe8af 451 Gene3D G3DSA:3.20.20.10 61 299 1.9E-65 T 29-03-2018 IPR029066 PLP-binding barrel SMALA_RS31740 81caf7dee5f981a344884385e55fe8af 451 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 63 314 7.1E-60 T 29-03-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 SMALA_RS31740 81caf7dee5f981a344884385e55fe8af 451 SUPERFAMILY SSF51419 53 317 2.88E-72 T 29-03-2018 IPR029066 PLP-binding barrel SMALA_RS31740 81caf7dee5f981a344884385e55fe8af 451 Gene3D G3DSA:2.40.37.10 300 451 7.6E-44 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 SMALA_RS28335 434c95a7efd1c4d64e7f6cd428b2ac2b 506 Gene3D G3DSA:3.40.605.10 3 274 3.4E-97 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS28335 434c95a7efd1c4d64e7f6cd428b2ac2b 506 Pfam PF00171 Aldehyde dehydrogenase family 28 484 2.2E-171 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS28335 434c95a7efd1c4d64e7f6cd428b2ac2b 506 Gene3D G3DSA:3.40.309.10 275 470 1.9E-69 T 29-03-2018 SMALA_RS28335 434c95a7efd1c4d64e7f6cd428b2ac2b 506 SUPERFAMILY SSF53720 15 488 1.03E-160 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMALA_RS28335 434c95a7efd1c4d64e7f6cd428b2ac2b 506 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 258 265 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 SMALA_RS28335 434c95a7efd1c4d64e7f6cd428b2ac2b 506 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 286 297 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 SMALA_RS30520 7dbb31eb9cde495a2a7eb3c11646cd39 289 TIGRFAM TIGR02962 hdxy_isourate: hydroxyisourate hydrolase 184 289 1.1E-28 T 29-03-2018 IPR014306 Hydroxyisourate hydrolase GO:0006144|GO:0033971 KEGG: 00230+3.5.2.17|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 SMALA_RS30520 7dbb31eb9cde495a2a7eb3c11646cd39 289 ProSitePatterns PS00768 Transthyretin signature 1. 188 203 - T 29-03-2018 IPR023418 Transthyretin, thyroxine binding site Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 SMALA_RS30520 7dbb31eb9cde495a2a7eb3c11646cd39 289 ProSitePatterns PS00769 Transthyretin signature 2. 272 284 - T 29-03-2018 IPR023419 Transthyretin, conserved site Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 SMALA_RS30520 7dbb31eb9cde495a2a7eb3c11646cd39 289 Pfam PF00576 HIUase/Transthyretin family 185 288 3.1E-32 T 29-03-2018 IPR023416 Transthyretin/hydroxyisourate hydrolase, superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 SMALA_RS30520 7dbb31eb9cde495a2a7eb3c11646cd39 289 Pfam PF09349 OHCU decarboxylase 13 158 3.6E-33 T 29-03-2018 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 SMALA_RS30520 7dbb31eb9cde495a2a7eb3c11646cd39 289 TIGRFAM TIGR03180 UraD_2: OHCU decarboxylase 12 162 1.2E-48 T 29-03-2018 IPR017595 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase, type 2 SMALA_RS30520 7dbb31eb9cde495a2a7eb3c11646cd39 289 Gene3D G3DSA:2.60.40.180 177 289 6.2E-37 T 29-03-2018 IPR023416 Transthyretin/hydroxyisourate hydrolase, superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 SMALA_RS30520 7dbb31eb9cde495a2a7eb3c11646cd39 289 SUPERFAMILY SSF158694 8 162 2.22E-39 T 29-03-2018 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 SMALA_RS30520 7dbb31eb9cde495a2a7eb3c11646cd39 289 SUPERFAMILY SSF49472 183 289 7.72E-29 T 29-03-2018 IPR023416 Transthyretin/hydroxyisourate hydrolase, superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 SMALA_RS30520 7dbb31eb9cde495a2a7eb3c11646cd39 289 Gene3D G3DSA:1.10.3330.10 8 164 2.9E-42 T 29-03-2018 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 SMALA_RS42945 c5e81c7a72746cd6924f8ee8b8b2e430 187 Gene3D G3DSA:1.10.10.10 97 184 6.1E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS42945 c5e81c7a72746cd6924f8ee8b8b2e430 187 SUPERFAMILY SSF88946 21 108 4.71E-5 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS42945 c5e81c7a72746cd6924f8ee8b8b2e430 187 SUPERFAMILY SSF88659 118 175 1.07E-11 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS42945 c5e81c7a72746cd6924f8ee8b8b2e430 187 Gene3D G3DSA:1.10.1740.10 13 96 1.0E-6 T 29-03-2018 SMALA_RS42945 c5e81c7a72746cd6924f8ee8b8b2e430 187 Pfam PF08281 Sigma-70, region 4 125 175 2.2E-13 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS04400 2a2f07ec172f595421a5f3d07dac44d0 927 Gene3D G3DSA:1.10.10.10 872 925 1.0E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS04400 2a2f07ec172f595421a5f3d07dac44d0 927 Pfam PF13191 AAA ATPase domain 41 173 4.9E-15 T 29-03-2018 SMALA_RS04400 2a2f07ec172f595421a5f3d07dac44d0 927 Pfam PF00196 Bacterial regulatory proteins, luxR family 864 915 1.5E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS04400 2a2f07ec172f595421a5f3d07dac44d0 927 ProSitePatterns PS00622 LuxR-type HTH domain signature. 879 906 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS04400 2a2f07ec172f595421a5f3d07dac44d0 927 SMART SM00421 862 919 1.4E-17 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS04400 2a2f07ec172f595421a5f3d07dac44d0 927 Gene3D G3DSA:1.25.40.10 659 871 1.7E-13 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS04400 2a2f07ec172f595421a5f3d07dac44d0 927 Gene3D G3DSA:1.25.40.10 538 658 0.0032 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS04400 2a2f07ec172f595421a5f3d07dac44d0 927 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 18 29 - T 29-03-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 SMALA_RS04400 2a2f07ec172f595421a5f3d07dac44d0 927 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 879 895 7.3E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS04400 2a2f07ec172f595421a5f3d07dac44d0 927 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 895 907 7.3E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS04400 2a2f07ec172f595421a5f3d07dac44d0 927 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 865 879 7.3E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS04400 2a2f07ec172f595421a5f3d07dac44d0 927 SUPERFAMILY SSF48452 685 828 2.13E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS04400 2a2f07ec172f595421a5f3d07dac44d0 927 SUPERFAMILY SSF48452 614 640 2.13E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS04400 2a2f07ec172f595421a5f3d07dac44d0 927 SUPERFAMILY SSF52540 106 218 1.27E-7 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS04400 2a2f07ec172f595421a5f3d07dac44d0 927 SUPERFAMILY SSF52540 33 76 1.27E-7 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS04400 2a2f07ec172f595421a5f3d07dac44d0 927 Gene3D G3DSA:1.25.40.10 191 431 0.18 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS04400 2a2f07ec172f595421a5f3d07dac44d0 927 Gene3D G3DSA:3.40.50.300 18 187 6.8E-8 T 29-03-2018 SMALA_RS04400 2a2f07ec172f595421a5f3d07dac44d0 927 SUPERFAMILY SSF46894 854 916 9.52E-15 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS11980 2d0c574c271f6ee08aa4deba0edab9f3 225 Gene3D G3DSA:1.10.10.10 139 220 4.5E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS11980 2d0c574c271f6ee08aa4deba0edab9f3 225 Gene3D G3DSA:3.40.50.2300 2 138 5.2E-37 T 29-03-2018 SMALA_RS11980 2d0c574c271f6ee08aa4deba0edab9f3 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 161 175 4.7E-15 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS11980 2d0c574c271f6ee08aa4deba0edab9f3 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 191 203 4.7E-15 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS11980 2d0c574c271f6ee08aa4deba0edab9f3 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 175 191 4.7E-15 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS11980 2d0c574c271f6ee08aa4deba0edab9f3 225 Pfam PF00196 Bacterial regulatory proteins, luxR family 161 215 6.8E-20 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS11980 2d0c574c271f6ee08aa4deba0edab9f3 225 Pfam PF00072 Response regulator receiver domain 5 121 2.1E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS11980 2d0c574c271f6ee08aa4deba0edab9f3 225 SUPERFAMILY SSF52172 3 192 3.27E-34 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS11980 2d0c574c271f6ee08aa4deba0edab9f3 225 SMART SM00448 3 120 5.1E-32 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS11980 2d0c574c271f6ee08aa4deba0edab9f3 225 ProSitePatterns PS00622 LuxR-type HTH domain signature. 175 202 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS11980 2d0c574c271f6ee08aa4deba0edab9f3 225 SMART SM00421 158 215 1.0E-26 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS42135 db6486d9da713cc343cf315d42368304 291 SUPERFAMILY SSF56784 59 250 1.05E-35 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS42135 db6486d9da713cc343cf315d42368304 291 Gene3D G3DSA:3.40.50.1000 45 258 2.0E-28 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS42135 db6486d9da713cc343cf315d42368304 291 Pfam PF13419 Haloacid dehalogenase-like hydrolase 62 247 1.2E-18 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS41390 a4ecbfe1b71bb2625d5a0c6846bb198c 232 Gene3D G3DSA:1.10.10.60 1 65 1.3E-13 T 29-03-2018 SMALA_RS41390 a4ecbfe1b71bb2625d5a0c6846bb198c 232 SUPERFAMILY SSF48498 88 230 1.56E-18 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS41390 a4ecbfe1b71bb2625d5a0c6846bb198c 232 SUPERFAMILY SSF46689 10 74 9.75E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS41390 a4ecbfe1b71bb2625d5a0c6846bb198c 232 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 64 4.3E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS41390 a4ecbfe1b71bb2625d5a0c6846bb198c 232 Gene3D G3DSA:1.10.357.10 79 232 3.9E-28 T 29-03-2018 SMALA_RS41390 a4ecbfe1b71bb2625d5a0c6846bb198c 232 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 88 230 2.1E-6 T 29-03-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 SMALA_RS26965 c81e39277a80abda00a786ec79692af2 213 Gene3D G3DSA:1.10.10.60 2 62 1.3E-19 T 29-03-2018 SMALA_RS26965 c81e39277a80abda00a786ec79692af2 213 SUPERFAMILY SSF46689 5 77 7.98E-19 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS26965 c81e39277a80abda00a786ec79692af2 213 Gene3D G3DSA:1.10.357.10 63 196 1.5E-21 T 29-03-2018 SMALA_RS26965 c81e39277a80abda00a786ec79692af2 213 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 60 1.1E-15 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS26965 c81e39277a80abda00a786ec79692af2 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 4.7E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS26965 c81e39277a80abda00a786ec79692af2 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 4.7E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS33605 6b34bda4fb74acc1e58541539b6f9165 358 Gene3D G3DSA:3.40.50.720 289 353 1.1E-5 T 29-03-2018 SMALA_RS33605 6b34bda4fb74acc1e58541539b6f9165 358 Gene3D G3DSA:3.40.50.720 1 205 1.6E-33 T 29-03-2018 SMALA_RS33605 6b34bda4fb74acc1e58541539b6f9165 358 SUPERFAMILY SSF55347 192 298 7.06E-22 T 29-03-2018 SMALA_RS33605 6b34bda4fb74acc1e58541539b6f9165 358 Gene3D G3DSA:3.30.360.10 206 288 1.5E-22 T 29-03-2018 SMALA_RS33605 6b34bda4fb74acc1e58541539b6f9165 358 SUPERFAMILY SSF51735 295 348 3.68E-58 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS33605 6b34bda4fb74acc1e58541539b6f9165 358 SUPERFAMILY SSF51735 3 187 3.68E-58 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS33605 6b34bda4fb74acc1e58541539b6f9165 358 Pfam PF01658 Myo-inositol-1-phosphate synthase 193 298 1.1E-21 T 29-03-2018 IPR013021 Myo-inositol-1-phosphate synthase, GAPDH-like KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 SMALA_RS15815 19a5312f1cd1e1a1e354a11218ab5049 485 SUPERFAMILY SSF51735 243 405 5.92E-77 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS15815 19a5312f1cd1e1a1e354a11218ab5049 485 SMART SM00997 243 405 4.3E-110 T 29-03-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 SMALA_RS15815 19a5312f1cd1e1a1e354a11218ab5049 485 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 10 477 2.1E-193 T 29-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 SMALA_RS15815 19a5312f1cd1e1a1e354a11218ab5049 485 PIRSF PIRSF001109 1 485 9.4E-195 T 29-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 SMALA_RS15815 19a5312f1cd1e1a1e354a11218ab5049 485 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 265 281 - T 29-03-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 SMALA_RS15815 19a5312f1cd1e1a1e354a11218ab5049 485 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 9 484 2.6E-150 T 29-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 SMALA_RS15815 19a5312f1cd1e1a1e354a11218ab5049 485 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 243 405 7.7E-83 T 29-03-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 SMALA_RS15815 19a5312f1cd1e1a1e354a11218ab5049 485 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 5 477 49.79 T 29-03-2018 IPR034373 Adenosylhomocysteinase GO:0004013|GO:0019510|GO:0051287 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-2408508 SMALA_RS15815 19a5312f1cd1e1a1e354a11218ab5049 485 SMART SM00996 9 484 0.0 T 29-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 SMALA_RS15815 19a5312f1cd1e1a1e354a11218ab5049 485 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 81 95 - T 29-03-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 SMALA_RS15815 19a5312f1cd1e1a1e354a11218ab5049 485 Gene3D G3DSA:3.40.50.1480 1 262 9.3E-94 T 29-03-2018 SMALA_RS15815 19a5312f1cd1e1a1e354a11218ab5049 485 Gene3D G3DSA:3.40.50.1480 263 458 8.3E-84 T 29-03-2018 SMALA_RS15815 19a5312f1cd1e1a1e354a11218ab5049 485 SUPERFAMILY SSF52283 406 485 9.64E-116 T 29-03-2018 SMALA_RS15815 19a5312f1cd1e1a1e354a11218ab5049 485 SUPERFAMILY SSF52283 8 157 9.64E-116 T 29-03-2018 SMALA_RS15815 19a5312f1cd1e1a1e354a11218ab5049 485 SUPERFAMILY SSF52283 195 242 9.64E-116 T 29-03-2018 SMALA_RS23680 beaff0b1b13a9cb67c11eadaf48e8be4 253 Pfam PF08220 DeoR-like helix-turn-helix domain 6 56 1.5E-14 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMALA_RS23680 beaff0b1b13a9cb67c11eadaf48e8be4 253 SUPERFAMILY SSF46785 5 58 6.43E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS23680 beaff0b1b13a9cb67c11eadaf48e8be4 253 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 4.7E-9 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMALA_RS23680 beaff0b1b13a9cb67c11eadaf48e8be4 253 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 4.7E-9 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMALA_RS23680 beaff0b1b13a9cb67c11eadaf48e8be4 253 Gene3D G3DSA:3.40.50.1360 73 239 1.3E-39 T 29-03-2018 SMALA_RS23680 beaff0b1b13a9cb67c11eadaf48e8be4 253 SMART SM01134 73 234 1.4E-66 T 29-03-2018 SMALA_RS23680 beaff0b1b13a9cb67c11eadaf48e8be4 253 SUPERFAMILY SSF100950 76 235 6.17E-26 T 29-03-2018 SMALA_RS23680 beaff0b1b13a9cb67c11eadaf48e8be4 253 Gene3D G3DSA:1.10.10.10 1 62 1.9E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS23680 beaff0b1b13a9cb67c11eadaf48e8be4 253 Pfam PF00455 DeoR C terminal sensor domain 76 233 5.9E-49 T 29-03-2018 IPR014036 DeoR C-terminal sensor domain SMALA_RS23680 beaff0b1b13a9cb67c11eadaf48e8be4 253 SMART SM00420 6 58 1.0E-12 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMALA_RS21795 ccec5447c98d7475d353ceb4ca037021 346 PIRSF PIRSF016753 45 346 1.7E-103 T 29-03-2018 IPR016676 Phospholipid/glycerol acyltransferase, predicted SMALA_RS21795 ccec5447c98d7475d353ceb4ca037021 346 SMART SM00563 133 252 3.5E-17 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SMALA_RS21795 ccec5447c98d7475d353ceb4ca037021 346 Gene3D G3DSA:3.40.1130.10 89 343 1.0E-25 T 29-03-2018 SMALA_RS21795 ccec5447c98d7475d353ceb4ca037021 346 SUPERFAMILY SSF69593 107 337 4.84E-33 T 29-03-2018 SMALA_RS21795 ccec5447c98d7475d353ceb4ca037021 346 Pfam PF01553 Acyltransferase 118 249 7.0E-17 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SMALA_RS11680 965430ba60be0e1959c83457e588a079 229 Pfam PF09335 SNARE associated Golgi protein 65 171 6.0E-9 T 29-03-2018 IPR032816 SNARE associated Golgi protein SMALA_RS38615 55bb8370883bc69b0a5059c82aaab3d1 385 Pfam PF13193 AMP-binding enzyme C-terminal domain 295 372 1.5E-14 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS38615 55bb8370883bc69b0a5059c82aaab3d1 385 Gene3D G3DSA:3.30.300.30 280 385 1.2E-22 T 29-03-2018 SMALA_RS38615 55bb8370883bc69b0a5059c82aaab3d1 385 SUPERFAMILY SSF56801 37 384 3.79E-83 T 29-03-2018 SMALA_RS38615 55bb8370883bc69b0a5059c82aaab3d1 385 Pfam PF00501 AMP-binding enzyme 48 285 2.6E-46 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS38615 55bb8370883bc69b0a5059c82aaab3d1 385 ProSitePatterns PS00455 Putative AMP-binding domain signature. 56 67 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS38615 55bb8370883bc69b0a5059c82aaab3d1 385 Gene3D G3DSA:3.40.50.980 18 61 6.5E-4 T 29-03-2018 SMALA_RS38615 55bb8370883bc69b0a5059c82aaab3d1 385 Gene3D G3DSA:3.40.50.980 62 206 9.8E-29 T 29-03-2018 SMALA_RS38615 55bb8370883bc69b0a5059c82aaab3d1 385 Gene3D G3DSA:2.30.38.10 207 279 3.3E-21 T 29-03-2018 SMALA_RS10260 d24f3092c9c61ec5da57310f3fa8573d 184 SMART SM00947 43 181 1.2E-23 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SMALA_RS10260 d24f3092c9c61ec5da57310f3fa8573d 184 Pfam PF00484 Carbonic anhydrase 51 134 1.8E-11 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SMALA_RS10260 d24f3092c9c61ec5da57310f3fa8573d 184 SUPERFAMILY SSF53056 14 181 1.83E-35 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SMALA_RS10260 d24f3092c9c61ec5da57310f3fa8573d 184 Gene3D G3DSA:3.40.1050.10 20 181 6.5E-32 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SMALA_RS34195 5ea07b24a12ac7bc8ca773cab90a35e0 131 Pfam PF04341 Protein of unknown function, DUF485 37 123 2.3E-28 T 29-03-2018 IPR007436 Protein of unknown function DUF485 SMALA_RS02670 adec704adf0c5a076e20f7046d0ff28d 482 TIGRFAM TIGR00032 argG: argininosuccinate synthase 13 420 3.4E-137 T 29-03-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SMALA_RS02670 adec704adf0c5a076e20f7046d0ff28d 482 Gene3D G3DSA:1.10.287.400 378 438 7.2E-31 T 29-03-2018 IPR024073 Argininosuccinate synthetase mutimerisation domain, C-terminal tail GO:0042803 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400 SMALA_RS02670 adec704adf0c5a076e20f7046d0ff28d 482 Hamap MF_00581 Argininosuccinate synthase [argG]. 1 473 79.192 T 29-03-2018 IPR023437 Argininosuccinate synthase, type 2 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400 SMALA_RS02670 adec704adf0c5a076e20f7046d0ff28d 482 SUPERFAMILY SSF69864 190 438 1.83E-74 T 29-03-2018 SMALA_RS02670 adec704adf0c5a076e20f7046d0ff28d 482 Gene3D G3DSA:3.90.1260.10 179 374 2.9E-56 T 29-03-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SMALA_RS02670 adec704adf0c5a076e20f7046d0ff28d 482 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 129 140 - T 29-03-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SMALA_RS02670 adec704adf0c5a076e20f7046d0ff28d 482 SUPERFAMILY SSF52402 5 185 3.7E-30 T 29-03-2018 SMALA_RS02670 adec704adf0c5a076e20f7046d0ff28d 482 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 17 25 - T 29-03-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SMALA_RS02670 adec704adf0c5a076e20f7046d0ff28d 482 Pfam PF00764 Arginosuccinate synthase 16 404 2.9E-55 T 29-03-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SMALA_RS02670 adec704adf0c5a076e20f7046d0ff28d 482 Gene3D G3DSA:3.40.50.620 2 178 1.1E-16 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS29325 99e27a28de057a1492f2a4c4f0d54f63 277 Pfam PF08241 Methyltransferase domain 70 168 5.8E-23 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 SMALA_RS29325 99e27a28de057a1492f2a4c4f0d54f63 277 Gene3D G3DSA:3.40.50.150 30 276 1.8E-47 T 29-03-2018 SMALA_RS29325 99e27a28de057a1492f2a4c4f0d54f63 277 SUPERFAMILY SSF53335 10 261 1.25E-61 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS29325 99e27a28de057a1492f2a4c4f0d54f63 277 SMART SM00828 Methyltransferase in polyketide synthase (PKS) enzymes. 22 277 1.3E-4 T 29-03-2018 IPR020803 Polyketide synthase, methyltransferase domain SMALA_RS16770 ec6070eb21fb8294bc2166f1353e13b0 142 Pfam PF01797 Transposase IS200 like 14 131 1.6E-38 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 SMALA_RS16770 ec6070eb21fb8294bc2166f1353e13b0 142 SMART SM01321 14 131 2.7E-40 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 SMALA_RS16770 ec6070eb21fb8294bc2166f1353e13b0 142 Gene3D G3DSA:3.30.70.1290 4 130 4.9E-24 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 SMALA_RS16770 ec6070eb21fb8294bc2166f1353e13b0 142 SUPERFAMILY SSF143422 6 131 4.19E-43 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 SMALA_RS25525 646b44905bfc93f8f97021ceb3163588 61 Gene3D G3DSA:3.30.70.1070 5 54 1.0E-5 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 SMALA_RS25525 646b44905bfc93f8f97021ceb3163588 61 Pfam PF05036 Sporulation related domain 11 45 1.0E-4 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 SMALA_RS24595 c6762fcb32201d42975ecb6ff6a85e56 572 Gene3D G3DSA:2.60.120.260 41 186 1.6E-26 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS24595 c6762fcb32201d42975ecb6ff6a85e56 572 Pfam PF02018 Carbohydrate binding domain 48 163 4.8E-14 T 29-03-2018 IPR003305 Carbohydrate-binding, CenC-like GO:0016798 SMALA_RS24595 c6762fcb32201d42975ecb6ff6a85e56 572 Pfam PF00041 Fibronectin type III domain 190 261 5.2E-8 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 SMALA_RS24595 c6762fcb32201d42975ecb6ff6a85e56 572 Gene3D G3DSA:2.60.40.10 187 272 7.9E-21 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS24595 c6762fcb32201d42975ecb6ff6a85e56 572 SUPERFAMILY SSF51445 280 561 1.48E-54 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS24595 c6762fcb32201d42975ecb6ff6a85e56 572 SUPERFAMILY SSF49785 47 179 1.45E-12 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS24595 c6762fcb32201d42975ecb6ff6a85e56 572 PRINTS PR00014 Fibronectin type III repeat signature 245 259 3.2E-5 T 29-03-2018 SMALA_RS24595 c6762fcb32201d42975ecb6ff6a85e56 572 PRINTS PR00014 Fibronectin type III repeat signature 227 245 3.2E-5 T 29-03-2018 SMALA_RS24595 c6762fcb32201d42975ecb6ff6a85e56 572 PRINTS PR00014 Fibronectin type III repeat signature 202 211 3.2E-5 T 29-03-2018 SMALA_RS24595 c6762fcb32201d42975ecb6ff6a85e56 572 SMART SM00060 188 258 1.1E-13 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 SMALA_RS24595 c6762fcb32201d42975ecb6ff6a85e56 572 ProSitePatterns PS01095 Chitinases family 18 active site. 390 398 - T 29-03-2018 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 SMALA_RS24595 c6762fcb32201d42975ecb6ff6a85e56 572 SUPERFAMILY SSF49265 187 270 7.46E-19 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 SMALA_RS24595 c6762fcb32201d42975ecb6ff6a85e56 572 Pfam PF00704 Glycosyl hydrolases family 18 285 559 5.1E-32 T 29-03-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 SMALA_RS24595 c6762fcb32201d42975ecb6ff6a85e56 572 Gene3D G3DSA:3.20.20.80 277 570 1.5E-49 T 29-03-2018 SMALA_RS24595 c6762fcb32201d42975ecb6ff6a85e56 572 SMART SM00636 283 553 1.7E-7 T 29-03-2018 IPR011583 Chitinase II GO:0008061 SMALA_RS30305 fbdf576f7bf90aa6b5520bca3e1628c4 398 Gene3D G3DSA:1.10.630.10 11 395 8.2E-88 T 29-03-2018 SMALA_RS30305 fbdf576f7bf90aa6b5520bca3e1628c4 398 SUPERFAMILY SSF48264 4 396 7.73E-105 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS30305 fbdf576f7bf90aa6b5520bca3e1628c4 398 Pfam PF00067 Cytochrome P450 181 365 6.7E-27 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS30305 fbdf576f7bf90aa6b5520bca3e1628c4 398 PRINTS PR00359 B-class P450 signature 314 329 3.3E-62 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS30305 fbdf576f7bf90aa6b5520bca3e1628c4 398 PRINTS PR00359 B-class P450 signature 268 279 3.3E-62 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS30305 fbdf576f7bf90aa6b5520bca3e1628c4 398 PRINTS PR00359 B-class P450 signature 87 98 3.3E-62 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS30305 fbdf576f7bf90aa6b5520bca3e1628c4 398 PRINTS PR00359 B-class P450 signature 286 313 3.3E-62 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS30305 fbdf576f7bf90aa6b5520bca3e1628c4 398 PRINTS PR00359 B-class P450 signature 344 355 3.3E-62 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS30305 fbdf576f7bf90aa6b5520bca3e1628c4 398 PRINTS PR00359 B-class P450 signature 133 149 3.3E-62 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS30305 fbdf576f7bf90aa6b5520bca3e1628c4 398 PRINTS PR00359 B-class P450 signature 150 165 3.3E-62 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS30305 fbdf576f7bf90aa6b5520bca3e1628c4 398 PRINTS PR00359 B-class P450 signature 186 208 3.3E-62 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS30305 fbdf576f7bf90aa6b5520bca3e1628c4 398 PRINTS PR00359 B-class P450 signature 335 344 3.3E-62 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS30305 fbdf576f7bf90aa6b5520bca3e1628c4 398 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 337 346 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMALA_RS21730 4e02f61638e371c0f68d10d7c9b6a43e 269 Gene3D G3DSA:1.10.3730.10 163 268 9.4E-43 T 29-03-2018 SMALA_RS21730 4e02f61638e371c0f68d10d7c9b6a43e 269 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 160 264 8.0E-38 T 29-03-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 SMALA_RS21730 4e02f61638e371c0f68d10d7c9b6a43e 269 SUPERFAMILY SSF48179 159 265 4.93E-35 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMALA_RS21730 4e02f61638e371c0f68d10d7c9b6a43e 269 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 5 264 1.2E-78 T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 SMALA_RS21730 4e02f61638e371c0f68d10d7c9b6a43e 269 Gene3D G3DSA:3.40.50.720 1 162 4.0E-33 T 29-03-2018 SMALA_RS21730 4e02f61638e371c0f68d10d7c9b6a43e 269 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 4 97 1.1E-20 T 29-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal SMALA_RS21730 4e02f61638e371c0f68d10d7c9b6a43e 269 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 3 264 26.306 T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 SMALA_RS21730 4e02f61638e371c0f68d10d7c9b6a43e 269 PIRSF PIRSF000193 2 267 1.3E-75 T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 SMALA_RS21730 4e02f61638e371c0f68d10d7c9b6a43e 269 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 220 242 - T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 SMALA_RS21730 4e02f61638e371c0f68d10d7c9b6a43e 269 SUPERFAMILY SSF51735 4 158 3.66E-34 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS06410 414b107e2c3b88fe4b2dabe3269f98ed 293 Gene3D G3DSA:1.10.1040.10 192 293 3.5E-26 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMALA_RS06410 414b107e2c3b88fe4b2dabe3269f98ed 293 Gene3D G3DSA:3.40.50.720 2 191 2.0E-38 T 29-03-2018 SMALA_RS06410 414b107e2c3b88fe4b2dabe3269f98ed 293 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 14 190 2.9E-45 T 29-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 SMALA_RS06410 414b107e2c3b88fe4b2dabe3269f98ed 293 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 193 289 1.0E-27 T 29-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 SMALA_RS06410 414b107e2c3b88fe4b2dabe3269f98ed 293 SUPERFAMILY SSF48179 192 290 4.08E-29 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMALA_RS06410 414b107e2c3b88fe4b2dabe3269f98ed 293 SUPERFAMILY SSF51735 13 192 2.23E-39 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS06410 414b107e2c3b88fe4b2dabe3269f98ed 293 PIRSF PIRSF000105 6 293 8.8E-79 T 29-03-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 SMALA_RS33020 a1cffc1f63b5a4ae47e78946ae7f4705 889 Gene3D G3DSA:3.30.930.10 1 245 1.0E-100 T 29-03-2018 SMALA_RS33020 a1cffc1f63b5a4ae47e78946ae7f4705 889 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 5 868 2.1E-258 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 SMALA_RS33020 a1cffc1f63b5a4ae47e78946ae7f4705 889 SUPERFAMILY SSF50447 462 560 1.62E-16 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain SMALA_RS33020 a1cffc1f63b5a4ae47e78946ae7f4705 889 Pfam PF02272 DHHA1 domain 746 884 3.0E-21 T 29-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 SMALA_RS33020 a1cffc1f63b5a4ae47e78946ae7f4705 889 PRINTS PR00980 Alanyl-tRNA synthetase signature 196 207 1.4E-28 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 SMALA_RS33020 a1cffc1f63b5a4ae47e78946ae7f4705 889 PRINTS PR00980 Alanyl-tRNA synthetase signature 69 80 1.4E-28 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 SMALA_RS33020 a1cffc1f63b5a4ae47e78946ae7f4705 889 PRINTS PR00980 Alanyl-tRNA synthetase signature 303 316 1.4E-28 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 SMALA_RS33020 a1cffc1f63b5a4ae47e78946ae7f4705 889 PRINTS PR00980 Alanyl-tRNA synthetase signature 229 242 1.4E-28 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 SMALA_RS33020 a1cffc1f63b5a4ae47e78946ae7f4705 889 PRINTS PR00980 Alanyl-tRNA synthetase signature 279 295 1.4E-28 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 SMALA_RS33020 a1cffc1f63b5a4ae47e78946ae7f4705 889 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 662 705 1.4E-17 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 SMALA_RS33020 a1cffc1f63b5a4ae47e78946ae7f4705 889 SUPERFAMILY SSF55186 561 720 1.57E-42 T 29-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 SMALA_RS33020 a1cffc1f63b5a4ae47e78946ae7f4705 889 Pfam PF01411 tRNA synthetases class II (A) 5 563 3.4E-197 T 29-03-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 SMALA_RS33020 a1cffc1f63b5a4ae47e78946ae7f4705 889 Gene3D G3DSA:3.30.980.10 562 722 4.8E-41 T 29-03-2018 SMALA_RS33020 a1cffc1f63b5a4ae47e78946ae7f4705 889 SUPERFAMILY SSF55681 2 248 1.04E-90 T 29-03-2018 SMALA_RS33020 a1cffc1f63b5a4ae47e78946ae7f4705 889 SMART SM00863 662 705 6.5E-21 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 SMALA_RS33020 a1cffc1f63b5a4ae47e78946ae7f4705 889 SUPERFAMILY SSF101353 249 463 1.44E-60 T 29-03-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 SMALA_RS33020 a1cffc1f63b5a4ae47e78946ae7f4705 889 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 889 168.464 T 29-03-2018 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 SMALA_RS38990 76ba271c21dba9e4ef8b506adc17b6e4 286 Gene3D G3DSA:1.10.10.10 3 86 1.9E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS38990 76ba271c21dba9e4ef8b506adc17b6e4 286 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 64 9.3E-22 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS38990 76ba271c21dba9e4ef8b506adc17b6e4 286 Gene3D G3DSA:3.40.190.10 201 250 4.1E-6 T 29-03-2018 SMALA_RS38990 76ba271c21dba9e4ef8b506adc17b6e4 286 Gene3D G3DSA:3.40.190.10 89 191 5.8E-12 T 29-03-2018 SMALA_RS38990 76ba271c21dba9e4ef8b506adc17b6e4 286 Pfam PF03466 LysR substrate binding domain 94 275 9.6E-16 T 29-03-2018 IPR005119 LysR, substrate-binding SMALA_RS38990 76ba271c21dba9e4ef8b506adc17b6e4 286 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 3.3E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS38990 76ba271c21dba9e4ef8b506adc17b6e4 286 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 3.3E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS38990 76ba271c21dba9e4ef8b506adc17b6e4 286 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 3.3E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS38990 76ba271c21dba9e4ef8b506adc17b6e4 286 SUPERFAMILY SSF53850 106 280 3.06E-16 T 29-03-2018 SMALA_RS38990 76ba271c21dba9e4ef8b506adc17b6e4 286 SUPERFAMILY SSF46785 7 87 2.63E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS24535 f61ed9890c2b0882ea6e87f91f44355f 112 Pfam PF13411 MerR HTH family regulatory protein 18 81 7.8E-9 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS24535 f61ed9890c2b0882ea6e87f91f44355f 112 SMART SM00422 18 86 3.9E-4 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS24535 f61ed9890c2b0882ea6e87f91f44355f 112 SUPERFAMILY SSF46955 18 100 8.24E-11 T 29-03-2018 IPR009061 Putative DNA-binding domain SMALA_RS24535 f61ed9890c2b0882ea6e87f91f44355f 112 Gene3D G3DSA:1.10.1660.10 7 108 3.0E-15 T 29-03-2018 SMALA_RS23205 c58da653c1ba8988ce8adf5bf92ead21 580 Gene3D G3DSA:2.30.40.10 482 571 9.4E-11 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS23205 c58da653c1ba8988ce8adf5bf92ead21 580 Gene3D G3DSA:3.20.20.140 66 481 1.1E-56 T 29-03-2018 SMALA_RS23205 c58da653c1ba8988ce8adf5bf92ead21 580 SUPERFAMILY SSF51556 365 499 2.55E-55 T 29-03-2018 IPR032466 Metal-dependent hydrolase SMALA_RS23205 c58da653c1ba8988ce8adf5bf92ead21 580 SUPERFAMILY SSF51556 58 315 2.55E-55 T 29-03-2018 IPR032466 Metal-dependent hydrolase SMALA_RS23205 c58da653c1ba8988ce8adf5bf92ead21 580 Pfam PF07969 Amidohydrolase family 48 542 4.4E-66 T 29-03-2018 IPR013108 Amidohydrolase 3 SMALA_RS23205 c58da653c1ba8988ce8adf5bf92ead21 580 SUPERFAMILY SSF51338 2 57 4.32E-20 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS23205 c58da653c1ba8988ce8adf5bf92ead21 580 SUPERFAMILY SSF51338 499 566 4.32E-20 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS23205 c58da653c1ba8988ce8adf5bf92ead21 580 Gene3D G3DSA:2.30.40.10 1 65 2.2E-16 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS11070 122560a1582b1367731604bad645998f 214 PRINTS PR00088 Haem oxygenase signature 2 27 2.1E-31 T 29-03-2018 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 SMALA_RS11070 122560a1582b1367731604bad645998f 214 PRINTS PR00088 Haem oxygenase signature 115 136 2.1E-31 T 29-03-2018 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 SMALA_RS11070 122560a1582b1367731604bad645998f 214 PRINTS PR00088 Haem oxygenase signature 191 209 2.1E-31 T 29-03-2018 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 SMALA_RS11070 122560a1582b1367731604bad645998f 214 PRINTS PR00088 Haem oxygenase signature 62 87 2.1E-31 T 29-03-2018 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 SMALA_RS11070 122560a1582b1367731604bad645998f 214 PRINTS PR00088 Haem oxygenase signature 159 180 2.1E-31 T 29-03-2018 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 SMALA_RS11070 122560a1582b1367731604bad645998f 214 PRINTS PR00088 Haem oxygenase signature 37 62 2.1E-31 T 29-03-2018 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 SMALA_RS11070 122560a1582b1367731604bad645998f 214 SUPERFAMILY SSF48613 2 208 9.35E-57 T 29-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 SMALA_RS11070 122560a1582b1367731604bad645998f 214 PIRSF PIRSF000343 1 214 8.7E-65 T 29-03-2018 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 SMALA_RS11070 122560a1582b1367731604bad645998f 214 Pfam PF01126 Heme oxygenase 2 205 1.0E-61 T 29-03-2018 IPR016053 Haem oxygenase-like GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 SMALA_RS11070 122560a1582b1367731604bad645998f 214 Gene3D G3DSA:1.20.910.10 1 213 2.1E-62 T 29-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 SMALA_RS29455 7f8ae7c15f6c5e0dce434edb636dbb0a 248 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMALA_RS29455 7f8ae7c15f6c5e0dce434edb636dbb0a 248 Gene3D G3DSA:3.40.50.720 47 248 7.7E-68 T 29-03-2018 SMALA_RS29455 7f8ae7c15f6c5e0dce434edb636dbb0a 248 Gene3D G3DSA:3.40.50.720 2 46 3.6E-8 T 29-03-2018 SMALA_RS29455 7f8ae7c15f6c5e0dce434edb636dbb0a 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 4.4E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS29455 7f8ae7c15f6c5e0dce434edb636dbb0a 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 4.4E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS29455 7f8ae7c15f6c5e0dce434edb636dbb0a 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 4.4E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS29455 7f8ae7c15f6c5e0dce434edb636dbb0a 248 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 192 8.0E-6 T 29-03-2018 SMALA_RS29455 7f8ae7c15f6c5e0dce434edb636dbb0a 248 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 247 4.0E-68 T 29-03-2018 SMALA_RS29455 7f8ae7c15f6c5e0dce434edb636dbb0a 248 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 9 246 1.3E-96 T 29-03-2018 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 SMALA_RS29455 7f8ae7c15f6c5e0dce434edb636dbb0a 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 9.2E-46 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS29455 7f8ae7c15f6c5e0dce434edb636dbb0a 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 9.2E-46 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS29455 7f8ae7c15f6c5e0dce434edb636dbb0a 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 9.2E-46 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS29455 7f8ae7c15f6c5e0dce434edb636dbb0a 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 9.2E-46 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS29455 7f8ae7c15f6c5e0dce434edb636dbb0a 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 9.2E-46 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS29455 7f8ae7c15f6c5e0dce434edb636dbb0a 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 9.2E-46 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS29455 7f8ae7c15f6c5e0dce434edb636dbb0a 248 SUPERFAMILY SSF51735 6 248 7.82E-84 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 SUPERFAMILY SSF52151 2142 2273 7.06E-70 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 SUPERFAMILY SSF52151 2337 2432 7.06E-70 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 SUPERFAMILY SSF51735 2786 3029 1.47E-47 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 Gene3D G3DSA:3.40.47.10 1862 2023 1.6E-60 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 Gene3D G3DSA:3.40.47.10 300 461 5.5E-63 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 Gene3D G3DSA:3.40.47.10 3429 3590 1.4E-64 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 413 539 1.1E-12 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 3542 3658 8.4E-15 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1975 2106 2.0E-11 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 SUPERFAMILY SSF51735 1002 1212 3.7E-47 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 Pfam PF08659 KR domain 1225 1402 3.7E-53 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 Pfam PF08659 KR domain 4344 4522 2.6E-55 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 Pfam PF08659 KR domain 2791 2968 1.3E-56 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 SMART SM01294 3074 3141 1.6E-4 T 29-03-2018 SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 SMART SM01294 1506 1574 2.3E-4 T 29-03-2018 SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 SMART SM01294 4629 4696 1.2E-5 T 29-03-2018 SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 SUPERFAMILY SSF52151 3888 3982 2.3E-69 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 SUPERFAMILY SSF52151 3693 3824 2.3E-69 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3100 3115 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 SUPERFAMILY SSF55048 2272 2336 9.55E-10 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 Gene3D G3DSA:1.10.1200.10 1473 1587 4.8E-20 T 29-03-2018 SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 Gene3D G3DSA:3.40.366.10 2130 2323 9.4E-58 T 29-03-2018 SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 Gene3D G3DSA:3.40.366.10 2324 2444 6.8E-25 T 29-03-2018 SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 Gene3D G3DSA:3.40.366.10 3681 3875 1.3E-56 T 29-03-2018 SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 Gene3D G3DSA:3.40.366.10 562 753 2.4E-55 T 29-03-2018 SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1225 1404 3.4E-51 T 29-03-2018 SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4344 4523 4.0E-49 T 29-03-2018 SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2791 2970 1.1E-50 T 29-03-2018 SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 SUPERFAMILY SSF47336 3066 3177 1.44E-25 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 Pfam PF00698 Acyl transferase domain 2144 2472 2.8E-57 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 Pfam PF00698 Acyl transferase domain 3695 4021 3.1E-57 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 Pfam PF00698 Acyl transferase domain 576 904 2.5E-52 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1533 1548 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 SMART SM00823 Phosphopantetheine attachment site 1506 1578 2.8E-29 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 SMART SM00823 Phosphopantetheine attachment site 4628 4700 1.2E-32 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 SMART SM00823 Phosphopantetheine attachment site 3073 3145 2.5E-30 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 SUPERFAMILY SSF51735 4121 4327 2.09E-44 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 SUPERFAMILY SSF47336 1501 1612 2.62E-23 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 SUPERFAMILY SSF53901 1593 1962 3.43E-102 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 Gene3D G3DSA:3.40.366.10 754 874 4.4E-21 T 29-03-2018 SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 Gene3D G3DSA:3.40.50.720 4336 4595 2.3E-53 T 29-03-2018 SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 Gene3D G3DSA:3.40.50.720 1217 1472 1.3E-51 T 29-03-2018 SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 Gene3D G3DSA:3.40.50.720 2783 3042 7.5E-54 T 29-03-2018 SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 3697 4004 5.4E-118 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 578 885 1.2E-108 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2146 2453 1.7E-118 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 Gene3D G3DSA:3.40.366.10 3876 3993 3.9E-28 T 29-03-2018 SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 Gene3D G3DSA:1.10.1200.10 4620 4767 5.1E-20 T 29-03-2018 SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 Gene3D G3DSA:1.10.1200.10 3066 3164 7.9E-22 T 29-03-2018 SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 Pfam PF00550 Phosphopantetheine attachment site 4631 4696 6.1E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 Pfam PF00550 Phosphopantetheine attachment site 1509 1574 6.0E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 Pfam PF00550 Phosphopantetheine attachment site 3074 3141 2.3E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 SUPERFAMILY SSF51735 1222 1477 9.52E-46 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1760 1776 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 3327 3343 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 Gene3D G3DSA:3.40.47.10 1589 1859 4.4E-88 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 Gene3D G3DSA:3.40.47.10 3165 3426 1.2E-88 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 Gene3D G3DSA:3.40.47.10 27 297 1.4E-85 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 SMART SM00825 Beta-ketoacyl synthase 3166 3592 2.2E-226 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 SMART SM00825 Beta-ketoacyl synthase 37 463 2.6E-219 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 SMART SM00825 Beta-ketoacyl synthase 1599 2025 5.3E-221 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 Pfam PF08990 Erythronolide synthase docking 4 27 6.4E-12 T 29-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 SUPERFAMILY SSF53901 33 400 2.24E-104 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 SUPERFAMILY SSF51735 2567 2779 2.72E-49 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1855 1972 2.0E-42 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 293 410 4.5E-44 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 3422 3539 2.0E-45 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 SUPERFAMILY SSF47336 4622 4705 8.38E-21 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 SUPERFAMILY SSF53901 3160 3536 6.52E-105 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 SUPERFAMILY SSF51735 4338 4583 3.57E-47 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 SUPERFAMILY SSF55048 3823 3887 6.54E-11 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 SUPERFAMILY SSF52151 769 863 1.12E-65 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 SUPERFAMILY SSF52151 575 705 1.12E-65 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 SUPERFAMILY SSF55048 704 768 3.27E-10 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3164 3414 1.5E-94 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1597 1847 2.2E-91 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS36770 c4ad90e481f2bd1d94218b955aa35b1a 4787 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 35 285 1.3E-89 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS05390 93cc1add2c3ad3210401b1b22e0ddbbf 262 ProSitePatterns PS00894 DeoR-type HTH domain signature. 14 48 - T 29-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 SMALA_RS05390 93cc1add2c3ad3210401b1b22e0ddbbf 262 Pfam PF00455 DeoR C terminal sensor domain 83 236 7.8E-36 T 29-03-2018 IPR014036 DeoR C-terminal sensor domain SMALA_RS05390 93cc1add2c3ad3210401b1b22e0ddbbf 262 SUPERFAMILY SSF46785 12 73 8.41E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS05390 93cc1add2c3ad3210401b1b22e0ddbbf 262 SMART SM00420 14 66 1.5E-13 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMALA_RS05390 93cc1add2c3ad3210401b1b22e0ddbbf 262 Gene3D G3DSA:1.10.10.10 6 80 2.6E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS05390 93cc1add2c3ad3210401b1b22e0ddbbf 262 SUPERFAMILY SSF100950 83 236 2.62E-18 T 29-03-2018 SMALA_RS05390 93cc1add2c3ad3210401b1b22e0ddbbf 262 Pfam PF08220 DeoR-like helix-turn-helix domain 14 65 2.1E-13 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMALA_RS05390 93cc1add2c3ad3210401b1b22e0ddbbf 262 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 46 64 1.6E-7 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMALA_RS05390 93cc1add2c3ad3210401b1b22e0ddbbf 262 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 32 46 1.6E-7 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMALA_RS05390 93cc1add2c3ad3210401b1b22e0ddbbf 262 Gene3D G3DSA:3.40.50.1360 81 249 8.1E-26 T 29-03-2018 SMALA_RS05390 93cc1add2c3ad3210401b1b22e0ddbbf 262 SMART SM01134 81 241 1.2E-43 T 29-03-2018 SMALA_RS27800 98aa49c000128a8329a5eb293869cbeb 347 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 7 329 9.2E-89 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 SMALA_RS27800 98aa49c000128a8329a5eb293869cbeb 347 SUPERFAMILY SSF53659 4 344 4.03E-110 T 29-03-2018 SMALA_RS27800 98aa49c000128a8329a5eb293869cbeb 347 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 239 258 - T 29-03-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 SMALA_RS27800 98aa49c000128a8329a5eb293869cbeb 347 Gene3D G3DSA:3.40.718.10 210 346 1.6E-47 T 29-03-2018 SMALA_RS27800 98aa49c000128a8329a5eb293869cbeb 347 Gene3D G3DSA:3.40.718.10 1 209 9.1E-62 T 29-03-2018 SMALA_RS27800 98aa49c000128a8329a5eb293869cbeb 347 Hamap MF_01035 3-isopropylmalate dehydrogenase [leuB]. 5 345 59.623 T 29-03-2018 IPR023698 3-isopropylmalate dehydrogenase GO:0003862|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 SMALA_RS27800 98aa49c000128a8329a5eb293869cbeb 347 SMART SM01329 6 341 3.3E-170 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 SMALA_RS00290 bbbec81abadfeda6afc5e3285861d4f1 406 TIGRFAM TIGR01976 am_tr_V_VC1184: cysteine desulfurase family protein 3 395 1.3E-145 T 29-03-2018 IPR011340 Cysteine desulfurase-related SMALA_RS00290 bbbec81abadfeda6afc5e3285861d4f1 406 Gene3D G3DSA:3.40.640.10 29 263 1.0E-48 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS00290 bbbec81abadfeda6afc5e3285861d4f1 406 SUPERFAMILY SSF53383 3 400 1.5E-83 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS00290 bbbec81abadfeda6afc5e3285861d4f1 406 Pfam PF00266 Aminotransferase class-V 22 391 2.2E-57 T 29-03-2018 IPR000192 Aminotransferase class V domain SMALA_RS00290 bbbec81abadfeda6afc5e3285861d4f1 406 Gene3D G3DSA:3.90.1150.10 264 398 4.1E-25 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS33645 004be5d7657752cfe9df750d78808eeb 85 SUPERFAMILY SSF47336 10 84 4.45E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS33645 004be5d7657752cfe9df750d78808eeb 85 Pfam PF00550 Phosphopantetheine attachment site 12 77 8.4E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS33645 004be5d7657752cfe9df750d78808eeb 85 Gene3D G3DSA:1.10.1200.10 2 85 8.5E-14 T 29-03-2018 SMALA_RS14885 b2bc558be07c0e1f2f4077642e414ba9 242 Pfam PF04203 Sortase family 84 224 2.6E-17 T 29-03-2018 IPR005754 Sortase family SMALA_RS14885 b2bc558be07c0e1f2f4077642e414ba9 242 SUPERFAMILY SSF63817 70 224 2.75E-14 T 29-03-2018 IPR023365 Sortase domain SMALA_RS14885 b2bc558be07c0e1f2f4077642e414ba9 242 Gene3D G3DSA:2.40.260.10 71 230 4.1E-24 T 29-03-2018 IPR023365 Sortase domain SMALA_RS40365 d62dea309d21365c73aeb1d98f8c6db1 399 SUPERFAMILY SSF54373 225 327 1.31E-9 T 29-03-2018 SMALA_RS40365 d62dea309d21365c73aeb1d98f8c6db1 399 Pfam PF01266 FAD dependent oxidoreductase 5 366 1.8E-61 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 SMALA_RS40365 d62dea309d21365c73aeb1d98f8c6db1 399 Gene3D G3DSA:3.30.9.10 167 326 2.4E-31 T 29-03-2018 SMALA_RS40365 d62dea309d21365c73aeb1d98f8c6db1 399 SUPERFAMILY SSF51905 4 225 1.88E-49 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS40365 d62dea309d21365c73aeb1d98f8c6db1 399 SUPERFAMILY SSF51905 327 384 1.88E-49 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS40365 d62dea309d21365c73aeb1d98f8c6db1 399 Gene3D G3DSA:3.30.9.10 93 166 5.7E-8 T 29-03-2018 SMALA_RS40365 d62dea309d21365c73aeb1d98f8c6db1 399 Gene3D G3DSA:3.40.50.720 1 54 1.2E-4 T 29-03-2018 SMALA_RS17945 b030fcfaa982686c220a2ca7f2a5b654 832 Gene3D G3DSA:3.40.50.300 217 367 1.4E-9 T 29-03-2018 SMALA_RS17945 b030fcfaa982686c220a2ca7f2a5b654 832 Pfam PF05729 NACHT domain 227 387 5.9E-27 T 29-03-2018 SMALA_RS17945 b030fcfaa982686c220a2ca7f2a5b654 832 SUPERFAMILY SSF52540 222 404 2.79E-13 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS01675 8e278c4ebf603f9390acd0b4c8995a75 322 Gene3D G3DSA:3.40.800.10 5 319 1.3E-109 T 29-03-2018 SMALA_RS01675 8e278c4ebf603f9390acd0b4c8995a75 322 SUPERFAMILY SSF52768 16 312 8.82E-103 T 29-03-2018 SMALA_RS01675 8e278c4ebf603f9390acd0b4c8995a75 322 Pfam PF00491 Arginase family 36 307 9.9E-93 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 SMALA_RS01675 8e278c4ebf603f9390acd0b4c8995a75 322 PRINTS PR00116 Arginase signature 236 265 1.9E-14 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 SMALA_RS01675 8e278c4ebf603f9390acd0b4c8995a75 322 PRINTS PR00116 Arginase signature 123 138 1.9E-14 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 SMALA_RS01675 8e278c4ebf603f9390acd0b4c8995a75 322 ProSitePatterns PS01053 Arginase family signature. 239 260 - T 29-03-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 SMALA_RS01675 8e278c4ebf603f9390acd0b4c8995a75 322 PIRSF PIRSF036979 12 315 3.7E-109 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 SMALA_RS01675 8e278c4ebf603f9390acd0b4c8995a75 322 TIGRFAM TIGR01230 agmatinase: agmatinase 34 308 5.4E-72 T 29-03-2018 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|Reactome: R-HSA-351143 SMALA_RS18690 2380ad8a11ef25b4f87891661fb9bcc4 312 Gene3D G3DSA:3.60.21.10 26 311 1.6E-17 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SMALA_RS18690 2380ad8a11ef25b4f87891661fb9bcc4 312 SUPERFAMILY SSF56300 44 306 3.3E-25 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SMALA_RS18690 2380ad8a11ef25b4f87891661fb9bcc4 312 Pfam PF00149 Calcineurin-like phosphoesterase 50 242 2.4E-6 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 SMALA_RS36710 b901df1c1f915203438f0dfd06e82047 4053 Pfam PF00550 Phosphopantetheine attachment site 1737 1803 1.2E-9 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS36710 b901df1c1f915203438f0dfd06e82047 4053 Pfam PF00550 Phosphopantetheine attachment site 3896 3962 1.6E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS36710 b901df1c1f915203438f0dfd06e82047 4053 SMART SM00826 2746 2916 5.5E-59 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS36710 b901df1c1f915203438f0dfd06e82047 4053 SMART SM00826 934 1112 4.1E-70 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS36710 b901df1c1f915203438f0dfd06e82047 4053 Pfam PF08659 KR domain 3605 3784 2.5E-55 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS36710 b901df1c1f915203438f0dfd06e82047 4053 Pfam PF08659 KR domain 1454 1632 3.1E-55 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS36710 b901df1c1f915203438f0dfd06e82047 4053 Gene3D G3DSA:1.10.1200.10 1732 1828 8.0E-18 T 29-03-2018 SMALA_RS36710 b901df1c1f915203438f0dfd06e82047 4053 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 196 212 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS36710 b901df1c1f915203438f0dfd06e82047 4053 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 35 283 1.6E-85 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS36710 b901df1c1f915203438f0dfd06e82047 4053 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1828 2078 1.3E-89 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS36710 b901df1c1f915203438f0dfd06e82047 4053 Gene3D G3DSA:3.40.366.10 2361 2505 3.1E-44 T 29-03-2018 SMALA_RS36710 b901df1c1f915203438f0dfd06e82047 4053 SMART SM00823 Phosphopantetheine attachment site 3894 3966 4.1E-31 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS36710 b901df1c1f915203438f0dfd06e82047 4053 SMART SM00823 Phosphopantetheine attachment site 1735 1807 2.9E-30 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS36710 b901df1c1f915203438f0dfd06e82047 4053 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3921 3936 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS36710 b901df1c1f915203438f0dfd06e82047 4053 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 291 407 3.2E-42 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS36710 b901df1c1f915203438f0dfd06e82047 4053 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2086 2203 2.9E-43 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS36710 b901df1c1f915203438f0dfd06e82047 4053 Gene3D G3DSA:3.40.47.10 1829 2090 6.2E-87 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS36710 b901df1c1f915203438f0dfd06e82047 4053 Gene3D G3DSA:3.40.47.10 27 295 1.4E-83 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS36710 b901df1c1f915203438f0dfd06e82047 4053 SUPERFAMILY SSF52151 2556 2650 1.94E-65 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS36710 b901df1c1f915203438f0dfd06e82047 4053 SUPERFAMILY SSF52151 2361 2492 1.94E-65 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS36710 b901df1c1f915203438f0dfd06e82047 4053 SUPERFAMILY SSF51735 1241 1435 5.51E-30 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS36710 b901df1c1f915203438f0dfd06e82047 4053 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 3310 3364 4.5E-5 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS36710 b901df1c1f915203438f0dfd06e82047 4053 SUPERFAMILY SSF55048 2491 2555 1.57E-10 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS36710 b901df1c1f915203438f0dfd06e82047 4053 SUPERFAMILY SSF55048 686 754 1.05E-10 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS36710 b901df1c1f915203438f0dfd06e82047 4053 Gene3D G3DSA:3.40.366.10 562 698 2.4E-40 T 29-03-2018 SMALA_RS36710 b901df1c1f915203438f0dfd06e82047 4053 SUPERFAMILY SSF47336 1733 1843 1.7E-21 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS36710 b901df1c1f915203438f0dfd06e82047 4053 Gene3D G3DSA:1.10.1200.10 3887 3977 2.0E-20 T 29-03-2018 SMALA_RS36710 b901df1c1f915203438f0dfd06e82047 4053 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1991 2007 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS36710 b901df1c1f915203438f0dfd06e82047 4053 SUPERFAMILY SSF51735 3387 3523 3.6E-37 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS36710 b901df1c1f915203438f0dfd06e82047 4053 SMART SM01294 3895 3962 5.7E-6 T 29-03-2018 SMALA_RS36710 b901df1c1f915203438f0dfd06e82047 4053 SMART SM01294 1736 1803 4.0E-5 T 29-03-2018 SMALA_RS36710 b901df1c1f915203438f0dfd06e82047 4053 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1454 1634 1.1E-52 T 29-03-2018 SMALA_RS36710 b901df1c1f915203438f0dfd06e82047 4053 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3605 3785 3.5E-52 T 29-03-2018 SMALA_RS36710 b901df1c1f915203438f0dfd06e82047 4053 SUPERFAMILY SSF101173 3 35 3.27E-8 T 29-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 SMALA_RS36710 b901df1c1f915203438f0dfd06e82047 4053 Pfam PF13602 Zinc-binding dehydrogenase 3463 3595 9.1E-19 T 29-03-2018 SMALA_RS36710 b901df1c1f915203438f0dfd06e82047 4053 Gene3D G3DSA:3.40.50.720 3585 3838 1.5E-44 T 29-03-2018 SMALA_RS36710 b901df1c1f915203438f0dfd06e82047 4053 Pfam PF00698 Acyl transferase domain 2363 2696 1.0E-54 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS36710 b901df1c1f915203438f0dfd06e82047 4053 Pfam PF00698 Acyl transferase domain 565 885 2.3E-81 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS36710 b901df1c1f915203438f0dfd06e82047 4053 SMART SM00825 Beta-ketoacyl synthase 37 461 3.7E-213 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS36710 b901df1c1f915203438f0dfd06e82047 4053 SMART SM00825 Beta-ketoacyl synthase 1830 2256 1.0E-226 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS36710 b901df1c1f915203438f0dfd06e82047 4053 SUPERFAMILY SSF51735 3602 3853 6.27E-43 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS36710 b901df1c1f915203438f0dfd06e82047 4053 SUPERFAMILY SSF51735 1451 1685 2.18E-40 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS36710 b901df1c1f915203438f0dfd06e82047 4053 SUPERFAMILY SSF50129 3294 3421 2.83E-25 T 29-03-2018 IPR011032 GroES-like SMALA_RS36710 b901df1c1f915203438f0dfd06e82047 4053 Gene3D G3DSA:3.30.70.250 699 746 1.2E-14 T 29-03-2018 SMALA_RS36710 b901df1c1f915203438f0dfd06e82047 4053 Gene3D G3DSA:3.30.70.250 2506 2545 4.4E-16 T 29-03-2018 SMALA_RS36710 b901df1c1f915203438f0dfd06e82047 4053 Gene3D G3DSA:3.10.129.10 2760 2868 0.0034 T 29-03-2018 SMALA_RS36710 b901df1c1f915203438f0dfd06e82047 4053 Gene3D G3DSA:3.10.129.10 967 1072 8.7E-5 T 29-03-2018 SMALA_RS36710 b901df1c1f915203438f0dfd06e82047 4053 Pfam PF08990 Erythronolide synthase docking 4 28 1.0E-11 T 29-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 SMALA_RS36710 b901df1c1f915203438f0dfd06e82047 4053 Gene3D G3DSA:3.40.50.720 1446 1691 1.3E-42 T 29-03-2018 SMALA_RS36710 b901df1c1f915203438f0dfd06e82047 4053 SUPERFAMILY SSF47336 3887 3973 7.85E-23 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS36710 b901df1c1f915203438f0dfd06e82047 4053 Gene3D G3DSA:3.40.366.10 2546 2665 6.3E-24 T 29-03-2018 SMALA_RS36710 b901df1c1f915203438f0dfd06e82047 4053 Gene3D G3DSA:3.90.180.10 3276 3584 7.7E-61 T 29-03-2018 SMALA_RS36710 b901df1c1f915203438f0dfd06e82047 4053 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 566 866 8.2E-110 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS36710 b901df1c1f915203438f0dfd06e82047 4053 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2365 2678 2.9E-114 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS36710 b901df1c1f915203438f0dfd06e82047 4053 SUPERFAMILY SSF52151 564 688 9.94E-62 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS36710 b901df1c1f915203438f0dfd06e82047 4053 SUPERFAMILY SSF52151 755 859 9.94E-62 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS36710 b901df1c1f915203438f0dfd06e82047 4053 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1762 1777 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS36710 b901df1c1f915203438f0dfd06e82047 4053 Pfam PF14765 Polyketide synthase dehydratase 934 1232 7.9E-48 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS36710 b901df1c1f915203438f0dfd06e82047 4053 Pfam PF14765 Polyketide synthase dehydratase 2773 3035 3.1E-44 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS36710 b901df1c1f915203438f0dfd06e82047 4053 SUPERFAMILY SSF53901 1824 2201 2.58E-102 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS36710 b901df1c1f915203438f0dfd06e82047 4053 SUPERFAMILY SSF51735 3045 3264 1.54E-27 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS36710 b901df1c1f915203438f0dfd06e82047 4053 Gene3D G3DSA:3.40.366.10 747 873 2.4E-23 T 29-03-2018 SMALA_RS36710 b901df1c1f915203438f0dfd06e82047 4053 Gene3D G3DSA:3.40.47.10 298 459 1.5E-59 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS36710 b901df1c1f915203438f0dfd06e82047 4053 Gene3D G3DSA:3.40.47.10 2093 2254 9.6E-62 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS36710 b901df1c1f915203438f0dfd06e82047 4053 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 411 528 2.4E-11 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS36710 b901df1c1f915203438f0dfd06e82047 4053 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2206 2323 2.8E-14 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS36710 b901df1c1f915203438f0dfd06e82047 4053 SMART SM00829 3289 3595 5.0E-181 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS36710 b901df1c1f915203438f0dfd06e82047 4053 SUPERFAMILY SSF53901 31 398 5.01E-102 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS41200 c70eaf1b2a219f3c2827b9b18a647030 598 Gene3D G3DSA:2.60.40.10 447 543 0.25 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS41200 c70eaf1b2a219f3c2827b9b18a647030 598 TIGRFAM TIGR03769 P_ac_wall_RPT: actinobacterial surface-anchored protein domain 188 228 3.1E-11 T 29-03-2018 IPR022435 Surface-anchored repeat, actinobacteria SMALA_RS41200 c70eaf1b2a219f3c2827b9b18a647030 598 Gene3D G3DSA:2.60.40.10 254 346 0.24 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS41200 c70eaf1b2a219f3c2827b9b18a647030 598 Gene3D G3DSA:2.60.40.10 68 229 0.22 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS40065 d2421f1096409d5380fadd1062e020b2 425 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 193 367 2.9E-51 T 29-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 SMALA_RS40065 d2421f1096409d5380fadd1062e020b2 425 Gene3D G3DSA:3.40.50.720 76 192 5.3E-24 T 29-03-2018 SMALA_RS40065 d2421f1096409d5380fadd1062e020b2 425 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 308 324 - T 29-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site SMALA_RS40065 d2421f1096409d5380fadd1062e020b2 425 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 113 401 2.3E-20 T 29-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 SMALA_RS40065 d2421f1096409d5380fadd1062e020b2 425 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 231 258 - T 29-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 SMALA_RS40065 d2421f1096409d5380fadd1062e020b2 425 Gene3D G3DSA:3.40.50.720 193 368 5.1E-53 T 29-03-2018 SMALA_RS40065 d2421f1096409d5380fadd1062e020b2 425 SUPERFAMILY SSF52283 98 217 6.17E-26 T 29-03-2018 SMALA_RS40065 d2421f1096409d5380fadd1062e020b2 425 SUPERFAMILY SSF51735 187 367 3.27E-50 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS21205 6a99b4a58c66326946e8b081150c0383 486 Gene3D G3DSA:1.25.40.10 231 479 1.9E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS34990 382cc7d2fd7a22ab5e4d1098d0367ede 261 Pfam PF04545 Sigma-70, region 4 207 255 2.3E-13 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS34990 382cc7d2fd7a22ab5e4d1098d0367ede 261 Gene3D G3DSA:1.10.1740.10 31 107 6.0E-16 T 29-03-2018 SMALA_RS34990 382cc7d2fd7a22ab5e4d1098d0367ede 261 SUPERFAMILY SSF88659 184 257 1.36E-13 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS34990 382cc7d2fd7a22ab5e4d1098d0367ede 261 Gene3D G3DSA:1.10.10.10 178 261 2.8E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS34990 382cc7d2fd7a22ab5e4d1098d0367ede 261 Gene3D G3DSA:1.10.10.10 109 163 8.7E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS34990 382cc7d2fd7a22ab5e4d1098d0367ede 261 Pfam PF04542 Sigma-70 region 2 44 108 7.4E-15 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS34990 382cc7d2fd7a22ab5e4d1098d0367ede 261 Pfam PF04539 Sigma-70 region 3 122 191 2.0E-7 T 29-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS34990 382cc7d2fd7a22ab5e4d1098d0367ede 261 SUPERFAMILY SSF88659 113 188 3.92E-11 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS34990 382cc7d2fd7a22ab5e4d1098d0367ede 261 SUPERFAMILY SSF88946 33 110 1.57E-21 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS34990 382cc7d2fd7a22ab5e4d1098d0367ede 261 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 37 256 4.5E-30 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS34990 382cc7d2fd7a22ab5e4d1098d0367ede 261 PRINTS PR00046 Major sigma-70 factor signature 64 77 9.2E-5 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS34990 382cc7d2fd7a22ab5e4d1098d0367ede 261 PRINTS PR00046 Major sigma-70 factor signature 210 222 9.2E-5 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS34990 382cc7d2fd7a22ab5e4d1098d0367ede 261 PRINTS PR00046 Major sigma-70 factor signature 227 242 9.2E-5 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS37665 fe96f864c444d41aee60d30f61e85b3a 645 Gene3D G3DSA:1.20.1560.10 23 339 1.1E-32 T 29-03-2018 SMALA_RS37665 fe96f864c444d41aee60d30f61e85b3a 645 Pfam PF00005 ABC transporter 488 540 5.6E-11 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS37665 fe96f864c444d41aee60d30f61e85b3a 645 Gene3D G3DSA:3.40.50.300 414 621 3.4E-32 T 29-03-2018 SMALA_RS37665 fe96f864c444d41aee60d30f61e85b3a 645 Pfam PF00664 ABC transporter transmembrane region 42 302 1.4E-22 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMALA_RS37665 fe96f864c444d41aee60d30f61e85b3a 645 SUPERFAMILY SSF52540 421 608 4.0E-35 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS37665 fe96f864c444d41aee60d30f61e85b3a 645 ProSitePatterns PS00211 ABC transporters family signature. 512 526 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS37665 fe96f864c444d41aee60d30f61e85b3a 645 SUPERFAMILY SSF90123 20 327 4.05E-44 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMALA_RS28930 caf41102bbcd4762cb0d661a854a51f8 500 SUPERFAMILY SSF52540 276 465 1.65E-42 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS28930 caf41102bbcd4762cb0d661a854a51f8 500 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 344 362 2.1E-6 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 SMALA_RS28930 caf41102bbcd4762cb0d661a854a51f8 500 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 277 297 2.1E-6 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 SMALA_RS28930 caf41102bbcd4762cb0d661a854a51f8 500 Hamap MF_00900 GTPase HflX [hflX]. 95 465 46.85 T 29-03-2018 IPR016496 GTPase HflX GO:0005525 SMALA_RS28930 caf41102bbcd4762cb0d661a854a51f8 500 Pfam PF01926 50S ribosome-binding GTPase 277 395 4.9E-20 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 SMALA_RS28930 caf41102bbcd4762cb0d661a854a51f8 500 Pfam PF13167 GTP-binding GTPase N-terminal 92 180 2.1E-31 T 29-03-2018 IPR025121 GTPase HflX, N-terminal SMALA_RS28930 caf41102bbcd4762cb0d661a854a51f8 500 Pfam PF16360 GTP-binding GTPase Middle Region 182 269 2.0E-28 T 29-03-2018 IPR032305 GTP-binding protein, middle domain SMALA_RS28930 caf41102bbcd4762cb0d661a854a51f8 500 PIRSF PIRSF006809 44 496 1.0E-156 T 29-03-2018 IPR016496 GTPase HflX GO:0005525 SMALA_RS28930 caf41102bbcd4762cb0d661a854a51f8 500 Gene3D G3DSA:3.40.50.300 244 445 5.5E-34 T 29-03-2018 SMALA_RS28930 caf41102bbcd4762cb0d661a854a51f8 500 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 76 435 3.8E-128 T 29-03-2018 IPR016496 GTPase HflX GO:0005525 SMALA_RS35490 95c175945e7c4301efed6ed23f2e4670 302 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 94 292 4.1E-17 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS35490 95c175945e7c4301efed6ed23f2e4670 302 SUPERFAMILY SSF160964 16 60 1.7E-5 T 29-03-2018 SMALA_RS35490 95c175945e7c4301efed6ed23f2e4670 302 SUPERFAMILY SSF161098 63 290 4.06E-58 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS35490 95c175945e7c4301efed6ed23f2e4670 302 Gene3D G3DSA:1.10.3720.10 70 300 2.3E-41 T 29-03-2018 SMALA_RS35490 95c175945e7c4301efed6ed23f2e4670 302 Gene3D G3DSA:1.20.58.370 3 53 9.3E-7 T 29-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain SMALA_RS33530 da4b403728e6321e9f0a97984224e4e9 785 Gene3D G3DSA:3.40.50.20 323 451 1.6E-10 T 29-03-2018 SMALA_RS33530 da4b403728e6321e9f0a97984224e4e9 785 Gene3D G3DSA:3.30.470.20 531 739 6.0E-21 T 29-03-2018 SMALA_RS33530 da4b403728e6321e9f0a97984224e4e9 785 Gene3D G3DSA:3.40.50.1100 140 305 1.2E-34 T 29-03-2018 SMALA_RS33530 da4b403728e6321e9f0a97984224e4e9 785 SUPERFAMILY SSF53686 5 306 7.07E-63 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMALA_RS33530 da4b403728e6321e9f0a97984224e4e9 785 Gene3D G3DSA:3.30.1490.20 452 530 1.9E-19 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SMALA_RS33530 da4b403728e6321e9f0a97984224e4e9 785 SUPERFAMILY SSF56059 441 654 4.95E-32 T 29-03-2018 SMALA_RS33530 da4b403728e6321e9f0a97984224e4e9 785 Gene3D G3DSA:3.40.50.1100 39 139 2.5E-18 T 29-03-2018 SMALA_RS33530 da4b403728e6321e9f0a97984224e4e9 785 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 8 290 1.1E-45 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMALA_RS33530 da4b403728e6321e9f0a97984224e4e9 785 SMART SM01209 447 627 0.0066 T 29-03-2018 SMALA_RS33530 da4b403728e6321e9f0a97984224e4e9 785 Pfam PF13535 ATP-grasp domain 483 630 2.9E-20 T 29-03-2018 SMALA_RS10045 a161c6c8b8201f4a673e542bf2fe5ac1 260 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 3 260 3.3E-108 T 29-03-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 SMALA_RS10045 a161c6c8b8201f4a673e542bf2fe5ac1 260 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 2 260 47.342 T 29-03-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 SMALA_RS10045 a161c6c8b8201f4a673e542bf2fe5ac1 260 SUPERFAMILY SSF51366 3 260 4.4E-82 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 SMALA_RS10045 a161c6c8b8201f4a673e542bf2fe5ac1 260 Gene3D G3DSA:3.20.20.70 5 256 3.0E-67 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS10045 a161c6c8b8201f4a673e542bf2fe5ac1 260 Pfam PF00977 Histidine biosynthesis protein 6 243 8.8E-86 T 29-03-2018 IPR006062 Histidine biosynthesis GO:0000105 SMALA_RS26895 49d4c121cf98515239cde504af653366 80 PRINTS PR00124 ATP synthase C subunit signature 54 79 6.8E-17 T 29-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMALA_RS26895 49d4c121cf98515239cde504af653366 80 PRINTS PR00124 ATP synthase C subunit signature 37 52 6.8E-17 T 29-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMALA_RS26895 49d4c121cf98515239cde504af653366 80 PRINTS PR00124 ATP synthase C subunit signature 16 35 6.8E-17 T 29-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMALA_RS26895 49d4c121cf98515239cde504af653366 80 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 24 78 1.2E-12 T 29-03-2018 IPR005953 ATP synthase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 SMALA_RS26895 49d4c121cf98515239cde504af653366 80 Hamap MF_01396 ATP synthase subunit c [atpH]. 14 79 14.471 T 29-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMALA_RS26895 49d4c121cf98515239cde504af653366 80 ProSitePatterns PS00605 ATP synthase c subunit signature. 44 65 - T 29-03-2018 IPR020537 ATP synthase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMALA_RS26895 49d4c121cf98515239cde504af653366 80 SUPERFAMILY SSF81333 19 78 2.88E-16 T 29-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 SMALA_RS26895 49d4c121cf98515239cde504af653366 80 Pfam PF00137 ATP synthase subunit C 21 77 5.3E-11 T 29-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 SMALA_RS26895 49d4c121cf98515239cde504af653366 80 Gene3D G3DSA:1.20.20.10 8 79 4.4E-17 T 29-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 SMALA_RS13605 0e3c654a8f0315a723fa899b4ebd5502 379 Gene3D G3DSA:1.10.600.10 7 379 3.1E-91 T 29-03-2018 IPR008949 Isoprenoid synthase domain SMALA_RS13605 0e3c654a8f0315a723fa899b4ebd5502 379 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 258 270 - T 29-03-2018 IPR033749 Polyprenyl synthetase, conserved site SMALA_RS13605 0e3c654a8f0315a723fa899b4ebd5502 379 Pfam PF00348 Polyprenyl synthetase 50 318 5.7E-58 T 29-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 SMALA_RS13605 0e3c654a8f0315a723fa899b4ebd5502 379 SUPERFAMILY SSF48576 27 83 5.76E-74 T 29-03-2018 IPR008949 Isoprenoid synthase domain SMALA_RS13605 0e3c654a8f0315a723fa899b4ebd5502 379 SUPERFAMILY SSF48576 121 378 5.76E-74 T 29-03-2018 IPR008949 Isoprenoid synthase domain SMALA_RS10705 c26f3b8992dbc0be32a485cecff141a8 254 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 16 31 2.1E-9 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS10705 c26f3b8992dbc0be32a485cecff141a8 254 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 49 64 2.1E-9 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS10705 c26f3b8992dbc0be32a485cecff141a8 254 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 64 79 2.1E-9 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS10705 c26f3b8992dbc0be32a485cecff141a8 254 Gene3D G3DSA:1.10.10.10 128 211 0.049 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS10705 c26f3b8992dbc0be32a485cecff141a8 254 Gene3D G3DSA:1.10.10.10 212 248 0.027 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS10705 c26f3b8992dbc0be32a485cecff141a8 254 Gene3D G3DSA:1.10.10.10 1 96 8.7E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS10705 c26f3b8992dbc0be32a485cecff141a8 254 SUPERFAMILY SSF46785 9 93 1.3E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS10705 c26f3b8992dbc0be32a485cecff141a8 254 SMART SM00418 14 93 2.8E-21 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS10705 c26f3b8992dbc0be32a485cecff141a8 254 Pfam PF12840 Helix-turn-helix domain 14 73 5.1E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS21345 dc3cf8037609aa7449aa115f8d9d4d58 258 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS21345 dc3cf8037609aa7449aa115f8d9d4d58 258 SMART SM00382 29 229 1.9E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS21345 dc3cf8037609aa7449aa115f8d9d4d58 258 Gene3D G3DSA:3.40.50.300 1 256 5.9E-57 T 29-03-2018 SMALA_RS21345 dc3cf8037609aa7449aa115f8d9d4d58 258 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 5 258 3.8E-113 T 29-03-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 SMALA_RS21345 dc3cf8037609aa7449aa115f8d9d4d58 258 Pfam PF00005 ABC transporter 21 176 8.4E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS21345 dc3cf8037609aa7449aa115f8d9d4d58 258 SUPERFAMILY SSF52540 5 246 2.08E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS04830 5c28d966176f9a82ebcc66e0ad1d27d2 336 Pfam PF00248 Aldo/keto reductase family 10 323 8.9E-51 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS04830 5c28d966176f9a82ebcc66e0ad1d27d2 336 Gene3D G3DSA:3.20.20.100 4 333 2.5E-59 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS04830 5c28d966176f9a82ebcc66e0ad1d27d2 336 SUPERFAMILY SSF51430 9 324 1.01E-62 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS10740 f9ffd00341087bbab46fbac22a32c736 469 Pfam PF00120 Glutamine synthetase, catalytic domain 102 466 3.9E-138 T 29-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SMALA_RS10740 f9ffd00341087bbab46fbac22a32c736 469 SUPERFAMILY SSF55931 102 468 1.28E-138 T 29-03-2018 SMALA_RS10740 f9ffd00341087bbab46fbac22a32c736 469 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 16 94 5.4E-23 T 29-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SMALA_RS10740 f9ffd00341087bbab46fbac22a32c736 469 ProSitePatterns PS00180 Glutamine synthetase signature 1. 49 67 - T 29-03-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 SMALA_RS10740 f9ffd00341087bbab46fbac22a32c736 469 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 256 271 - T 29-03-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 SMALA_RS10740 f9ffd00341087bbab46fbac22a32c736 469 SUPERFAMILY SSF54368 5 99 7.59E-29 T 29-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SMALA_RS10740 f9ffd00341087bbab46fbac22a32c736 469 SMART SM01230 101 378 1.1E-152 T 29-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SMALA_RS10740 f9ffd00341087bbab46fbac22a32c736 469 Gene3D G3DSA:3.10.20.70 4 103 1.1E-24 T 29-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SMALA_RS10740 f9ffd00341087bbab46fbac22a32c736 469 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 8 468 7.9E-201 T 29-03-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SMALA_RS10740 f9ffd00341087bbab46fbac22a32c736 469 ProSitePatterns PS00182 Glutamine synthetase class-I adenylation site. 385 397 - T 29-03-2018 IPR001637 Glutamine synthetase class-I, adenylation site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SMALA_RS10740 f9ffd00341087bbab46fbac22a32c736 469 Gene3D G3DSA:3.30.590.10 104 456 4.6E-127 T 29-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 SMALA_RS41555 e6d7f7b989460559ecc191026fe64692 318 Pfam PF04909 Amidohydrolase 33 317 4.2E-48 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 SMALA_RS41555 e6d7f7b989460559ecc191026fe64692 318 SUPERFAMILY SSF51556 37 317 2.25E-79 T 29-03-2018 IPR032466 Metal-dependent hydrolase SMALA_RS41555 e6d7f7b989460559ecc191026fe64692 318 Gene3D G3DSA:3.20.20.140 19 317 7.8E-61 T 29-03-2018 SMALA_RS14400 7253571038cc3c422bb0293b7b8c2d4c 348 SMART SM00354 13 83 1.1E-28 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS14400 7253571038cc3c422bb0293b7b8c2d4c 348 Pfam PF13377 Periplasmic binding protein-like domain 184 348 1.8E-34 T 29-03-2018 SMALA_RS14400 7253571038cc3c422bb0293b7b8c2d4c 348 Gene3D G3DSA:1.10.10.60 3 27 5.3E-4 T 29-03-2018 SMALA_RS14400 7253571038cc3c422bb0293b7b8c2d4c 348 Gene3D G3DSA:1.10.260.40 28 69 1.2E-20 T 29-03-2018 SMALA_RS14400 7253571038cc3c422bb0293b7b8c2d4c 348 ProSitePatterns PS00356 LacI-type HTH domain signature. 16 34 - T 29-03-2018 SMALA_RS14400 7253571038cc3c422bb0293b7b8c2d4c 348 Gene3D G3DSA:3.40.50.2300 179 348 3.2E-52 T 29-03-2018 SMALA_RS14400 7253571038cc3c422bb0293b7b8c2d4c 348 SUPERFAMILY SSF47413 13 70 1.87E-17 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS14400 7253571038cc3c422bb0293b7b8c2d4c 348 Gene3D G3DSA:3.40.50.2300 70 178 1.8E-24 T 29-03-2018 SMALA_RS14400 7253571038cc3c422bb0293b7b8c2d4c 348 SUPERFAMILY SSF53822 86 347 1.2E-66 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SMALA_RS14400 7253571038cc3c422bb0293b7b8c2d4c 348 Pfam PF00356 Bacterial regulatory proteins, lacI family 15 60 7.5E-18 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS03215 bc7a8976c63e063476ccfec591dbf925 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 250 8.1E-62 T 29-03-2018 SMALA_RS03215 bc7a8976c63e063476ccfec591dbf925 253 Gene3D G3DSA:3.40.50.10090 3 45 5.9E-7 T 29-03-2018 SMALA_RS03215 bc7a8976c63e063476ccfec591dbf925 253 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 185 2.0E-6 T 29-03-2018 SMALA_RS03215 bc7a8976c63e063476ccfec591dbf925 253 Gene3D G3DSA:3.40.50.720 46 252 1.7E-63 T 29-03-2018 SMALA_RS03215 bc7a8976c63e063476ccfec591dbf925 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 1.8E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS03215 bc7a8976c63e063476ccfec591dbf925 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 1.8E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS03215 bc7a8976c63e063476ccfec591dbf925 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.8E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS03215 bc7a8976c63e063476ccfec591dbf925 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 1.8E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS03215 bc7a8976c63e063476ccfec591dbf925 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 1.8E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS03215 bc7a8976c63e063476ccfec591dbf925 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.8E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS03215 bc7a8976c63e063476ccfec591dbf925 253 SUPERFAMILY SSF51735 5 250 6.47E-80 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS03215 bc7a8976c63e063476ccfec591dbf925 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 4.8E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS03215 bc7a8976c63e063476ccfec591dbf925 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 4.8E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS03215 bc7a8976c63e063476ccfec591dbf925 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 4.8E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS03215 bc7a8976c63e063476ccfec591dbf925 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMALA_RS38010 afab54e47d7a82dd3c167dc94f7ebcb6 337 SUPERFAMILY SSF52540 17 265 3.91E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS38010 afab54e47d7a82dd3c167dc94f7ebcb6 337 ProSitePatterns PS00211 ABC transporters family signature. 167 181 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS38010 afab54e47d7a82dd3c167dc94f7ebcb6 337 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 246 310 2.0E-19 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMALA_RS38010 afab54e47d7a82dd3c167dc94f7ebcb6 337 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 245 330 3.0E-26 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMALA_RS38010 afab54e47d7a82dd3c167dc94f7ebcb6 337 Pfam PF00005 ABC transporter 37 194 2.0E-23 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS38010 afab54e47d7a82dd3c167dc94f7ebcb6 337 SMART SM00382 45 244 1.3E-18 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS38010 afab54e47d7a82dd3c167dc94f7ebcb6 337 Gene3D G3DSA:3.40.50.300 14 337 8.6E-72 T 29-03-2018 SMALA_RS36890 f7d4167ad284d5eb2603fde572e1f39a 720 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 154 639 2.9E-105 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMALA_RS36890 f7d4167ad284d5eb2603fde572e1f39a 720 SUPERFAMILY SSF54665 6 131 6.41E-33 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMALA_RS36890 f7d4167ad284d5eb2603fde572e1f39a 720 Gene3D G3DSA:3.30.365.10 262 412 6.4E-37 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMALA_RS36890 f7d4167ad284d5eb2603fde572e1f39a 720 Gene3D G3DSA:3.90.1170.50 6 128 7.2E-30 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMALA_RS36890 f7d4167ad284d5eb2603fde572e1f39a 720 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 22 128 1.6E-18 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMALA_RS36890 f7d4167ad284d5eb2603fde572e1f39a 720 SMART SM01008 22 128 4.5E-29 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMALA_RS36890 f7d4167ad284d5eb2603fde572e1f39a 720 Gene3D G3DSA:3.30.365.10 436 543 8.4E-19 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMALA_RS36890 f7d4167ad284d5eb2603fde572e1f39a 720 SUPERFAMILY SSF56003 125 701 5.63E-151 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMALA_RS36890 f7d4167ad284d5eb2603fde572e1f39a 720 Gene3D G3DSA:3.30.365.10 155 261 1.0E-31 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMALA_RS36890 f7d4167ad284d5eb2603fde572e1f39a 720 Gene3D G3DSA:3.30.365.10 544 706 1.3E-43 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMALA_RS15830 1b148160a2f1523c062b69cc3d324a08 398 Pfam PF01238 Phosphomannose isomerase type I 3 360 1.2E-70 T 29-03-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 SMALA_RS15830 1b148160a2f1523c062b69cc3d324a08 398 PRINTS PR00714 Phosphomannose isomerase type I signature 262 281 1.4E-63 T 29-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 SMALA_RS15830 1b148160a2f1523c062b69cc3d324a08 398 PRINTS PR00714 Phosphomannose isomerase type I signature 227 242 1.4E-63 T 29-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 SMALA_RS15830 1b148160a2f1523c062b69cc3d324a08 398 PRINTS PR00714 Phosphomannose isomerase type I signature 125 148 1.4E-63 T 29-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 SMALA_RS15830 1b148160a2f1523c062b69cc3d324a08 398 PRINTS PR00714 Phosphomannose isomerase type I signature 80 101 1.4E-63 T 29-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 SMALA_RS15830 1b148160a2f1523c062b69cc3d324a08 398 PRINTS PR00714 Phosphomannose isomerase type I signature 31 46 1.4E-63 T 29-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 SMALA_RS15830 1b148160a2f1523c062b69cc3d324a08 398 PRINTS PR00714 Phosphomannose isomerase type I signature 243 262 1.4E-63 T 29-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 SMALA_RS15830 1b148160a2f1523c062b69cc3d324a08 398 PRINTS PR00714 Phosphomannose isomerase type I signature 281 300 1.4E-63 T 29-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 SMALA_RS15830 1b148160a2f1523c062b69cc3d324a08 398 PRINTS PR00714 Phosphomannose isomerase type I signature 4 22 1.4E-63 T 29-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 SMALA_RS15830 1b148160a2f1523c062b69cc3d324a08 398 Gene3D G3DSA:1.10.441.10 162 269 8.8E-28 T 29-03-2018 SMALA_RS15830 1b148160a2f1523c062b69cc3d324a08 398 PIRSF PIRSF001480 1 398 3.4E-100 T 29-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 SMALA_RS15830 1b148160a2f1523c062b69cc3d324a08 398 TIGRFAM TIGR00218 manA: mannose-6-phosphate isomerase, class I 3 390 6.5E-76 T 29-03-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 SMALA_RS15830 1b148160a2f1523c062b69cc3d324a08 398 ProSitePatterns PS00965 Phosphomannose isomerase type I signature 1. 125 133 - T 29-03-2018 IPR018050 Phosphomannose isomerase, type I, conserved site GO:0004476 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 SMALA_RS15830 1b148160a2f1523c062b69cc3d324a08 398 Gene3D G3DSA:2.60.120.10 5 161 1.8E-50 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SMALA_RS15830 1b148160a2f1523c062b69cc3d324a08 398 SUPERFAMILY SSF51182 2 396 3.12E-99 T 29-03-2018 IPR011051 RmlC-like cupin domain SMALA_RS15830 1b148160a2f1523c062b69cc3d324a08 398 Gene3D G3DSA:2.60.120.10 300 398 7.8E-26 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SMALA_RS36850 497e2fa0d5526d74d7967e6d3df68c79 937 Gene3D G3DSA:3.40.50.300 633 867 2.7E-58 T 29-03-2018 SMALA_RS36850 497e2fa0d5526d74d7967e6d3df68c79 937 SMART SM00939 367 594 4.6E-26 T 29-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 SMALA_RS36850 497e2fa0d5526d74d7967e6d3df68c79 937 Gene3D G3DSA:3.40.50.1820 31 375 5.4E-40 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS36850 497e2fa0d5526d74d7967e6d3df68c79 937 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 81 339 1.3E-17 T 29-03-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 SMALA_RS36850 497e2fa0d5526d74d7967e6d3df68c79 937 SMART SM00382 663 852 5.9E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS36850 497e2fa0d5526d74d7967e6d3df68c79 937 SUPERFAMILY SSF53474 35 184 2.26E-48 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS36850 497e2fa0d5526d74d7967e6d3df68c79 937 SUPERFAMILY SSF53474 271 379 2.26E-48 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS36850 497e2fa0d5526d74d7967e6d3df68c79 937 Pfam PF00005 ABC transporter 655 795 6.3E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS36850 497e2fa0d5526d74d7967e6d3df68c79 937 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 469 571 2.1E-15 T 29-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 SMALA_RS36850 497e2fa0d5526d74d7967e6d3df68c79 937 SUPERFAMILY SSF49785 410 584 1.04E-26 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS36850 497e2fa0d5526d74d7967e6d3df68c79 937 ProSitePatterns PS00211 ABC transporters family signature. 767 781 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS36850 497e2fa0d5526d74d7967e6d3df68c79 937 SUPERFAMILY SSF52540 626 858 1.78E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS36850 497e2fa0d5526d74d7967e6d3df68c79 937 Gene3D G3DSA:2.60.120.260 379 591 5.9E-31 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS16050 9f07b39def3675571e2b6b40b0003e54 338 SMART SM00829 18 336 6.3E-6 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS16050 9f07b39def3675571e2b6b40b0003e54 338 Gene3D G3DSA:3.40.50.720 152 280 2.7E-21 T 29-03-2018 SMALA_RS16050 9f07b39def3675571e2b6b40b0003e54 338 SUPERFAMILY SSF51735 128 303 4.41E-38 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS16050 9f07b39def3675571e2b6b40b0003e54 338 SUPERFAMILY SSF50129 6 140 4.02E-23 T 29-03-2018 IPR011032 GroES-like SMALA_RS16050 9f07b39def3675571e2b6b40b0003e54 338 Pfam PF16884 N-terminal domain of oxidoreductase 8 116 2.3E-19 T 29-03-2018 SMALA_RS16050 9f07b39def3675571e2b6b40b0003e54 338 Gene3D G3DSA:3.90.180.10 1 151 8.0E-26 T 29-03-2018 SMALA_RS16050 9f07b39def3675571e2b6b40b0003e54 338 Pfam PF00107 Zinc-binding dehydrogenase 161 293 2.3E-19 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMALA_RS38035 4449680e51a2026e760af2ea09421cc3 118 Gene3D G3DSA:3.10.450.50 8 117 1.0E-17 T 29-03-2018 SMALA_RS38035 4449680e51a2026e760af2ea09421cc3 118 SUPERFAMILY SSF54427 12 114 3.06E-14 T 29-03-2018 IPR032710 NTF2-like domain SMALA_RS38035 4449680e51a2026e760af2ea09421cc3 118 Pfam PF12680 SnoaL-like domain 17 111 1.7E-7 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain SMALA_RS32595 1a3fed8c173be2f749e083133ca87d96 272 Gene3D G3DSA:3.40.1280.10 105 270 3.3E-46 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal SMALA_RS32595 1a3fed8c173be2f749e083133ca87d96 272 SUPERFAMILY SSF75217 107 266 1.64E-37 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases SMALA_RS32595 1a3fed8c173be2f749e083133ca87d96 272 Gene3D G3DSA:3.30.1330.30 6 104 1.0E-22 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like SMALA_RS32595 1a3fed8c173be2f749e083133ca87d96 272 SUPERFAMILY SSF55315 6 106 8.71E-16 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like SMALA_RS32595 1a3fed8c173be2f749e083133ca87d96 272 Pfam PF00588 SpoU rRNA Methylase family 122 263 1.7E-33 T 29-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 SMALA_RS00605 1e46f764ae64f3a65b6fb8e1f103b9c3 65 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 7 60 8.0E-12 T 29-03-2018 SMALA_RS00605 1e46f764ae64f3a65b6fb8e1f103b9c3 65 Gene3D G3DSA:3.30.70.20 1 65 3.0E-7 T 29-03-2018 SMALA_RS00605 1e46f764ae64f3a65b6fb8e1f103b9c3 65 SUPERFAMILY SSF54862 3 62 8.38E-12 T 29-03-2018 SMALA_RS34145 6d0862e4f9739b3fb910f574dad96570 519 PRINTS PR01758 Capsule biosynthesis protein CapB signature 262 279 2.1E-32 T 29-03-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 SMALA_RS34145 6d0862e4f9739b3fb910f574dad96570 519 PRINTS PR01758 Capsule biosynthesis protein CapB signature 114 129 2.1E-32 T 29-03-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 SMALA_RS34145 6d0862e4f9739b3fb910f574dad96570 519 PRINTS PR01758 Capsule biosynthesis protein CapB signature 297 312 2.1E-32 T 29-03-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 SMALA_RS34145 6d0862e4f9739b3fb910f574dad96570 519 PRINTS PR01758 Capsule biosynthesis protein CapB signature 366 382 2.1E-32 T 29-03-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 SMALA_RS34145 6d0862e4f9739b3fb910f574dad96570 519 PRINTS PR01758 Capsule biosynthesis protein CapB signature 143 158 2.1E-32 T 29-03-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 SMALA_RS34145 6d0862e4f9739b3fb910f574dad96570 519 PRINTS PR01758 Capsule biosynthesis protein CapB signature 199 216 2.1E-32 T 29-03-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 SMALA_RS34145 6d0862e4f9739b3fb910f574dad96570 519 PRINTS PR01758 Capsule biosynthesis protein CapB signature 38 54 2.1E-32 T 29-03-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 SMALA_RS34145 6d0862e4f9739b3fb910f574dad96570 519 PRINTS PR01758 Capsule biosynthesis protein CapB signature 61 78 2.1E-32 T 29-03-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 SMALA_RS34145 6d0862e4f9739b3fb910f574dad96570 519 SUPERFAMILY SSF53623 35 198 3.27E-12 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMALA_RS34145 6d0862e4f9739b3fb910f574dad96570 519 TIGRFAM TIGR04012 poly_gGlu_PgsB: poly-gamma-glutamate synthase PgsB 7 387 4.2E-114 T 29-03-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 SMALA_RS34145 6d0862e4f9739b3fb910f574dad96570 519 Pfam PF08245 Mur ligase middle domain 41 195 5.6E-6 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMALA_RS34145 6d0862e4f9739b3fb910f574dad96570 519 Gene3D G3DSA:3.40.1190.10 35 246 5.9E-16 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMALA_RS38560 d0b6ba6f7b4eb9b585b7302540460150 215 Gene3D G3DSA:1.10.3210.10 16 200 3.1E-13 T 29-03-2018 SMALA_RS38560 d0b6ba6f7b4eb9b585b7302540460150 215 SUPERFAMILY SSF109604 30 138 5.23E-17 T 29-03-2018 SMALA_RS38560 d0b6ba6f7b4eb9b585b7302540460150 215 Pfam PF01966 HD domain 35 122 1.9E-9 T 29-03-2018 IPR006674 HD domain SMALA_RS09435 4a83b7dd7bf179b5c03e5bb56192160a 328 Hamap MF_02122 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [dapD]. 8 325 44.122 T 29-03-2018 IPR026586 Type 2 tetrahydrodipicolinate N-succinyltransferase family GO:0008666 KEGG: 00300+2.3.1.117 SMALA_RS09435 4a83b7dd7bf179b5c03e5bb56192160a 328 Pfam PF14789 Tetrahydrodipicolinate N-succinyltransferase middle 120 160 1.4E-16 T 29-03-2018 IPR032784 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, middle domain KEGG: 00300+2.3.1.117 SMALA_RS09435 4a83b7dd7bf179b5c03e5bb56192160a 328 Gene3D G3DSA:2.160.10.10 161 288 1.4E-18 T 29-03-2018 SMALA_RS09435 4a83b7dd7bf179b5c03e5bb56192160a 328 TIGRFAM TIGR03535 DapD_actino: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase 10 327 1.2E-153 T 29-03-2018 IPR019875 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, actinobacteria KEGG: 00300+2.3.1.117 SMALA_RS09435 4a83b7dd7bf179b5c03e5bb56192160a 328 Gene3D G3DSA:3.30.60.70 120 160 3.2E-17 T 29-03-2018 SMALA_RS09435 4a83b7dd7bf179b5c03e5bb56192160a 328 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 242 274 3.2E-14 T 29-03-2018 IPR001451 Hexapeptide repeat SMALA_RS09435 4a83b7dd7bf179b5c03e5bb56192160a 328 SUPERFAMILY SSF51161 80 308 8.38E-40 T 29-03-2018 IPR011004 Trimeric LpxA-like SMALA_RS12930 410dd44b5941ead52041c8547a753d87 119 PRINTS PR00332 Histidine triad family signature 10 26 5.6E-19 T 29-03-2018 IPR001310 Histidine triad (HIT) protein SMALA_RS12930 410dd44b5941ead52041c8547a753d87 119 PRINTS PR00332 Histidine triad family signature 99 109 5.6E-19 T 29-03-2018 IPR001310 Histidine triad (HIT) protein SMALA_RS12930 410dd44b5941ead52041c8547a753d87 119 PRINTS PR00332 Histidine triad family signature 31 49 5.6E-19 T 29-03-2018 IPR001310 Histidine triad (HIT) protein SMALA_RS12930 410dd44b5941ead52041c8547a753d87 119 Pfam PF01230 HIT domain 17 112 2.3E-24 T 29-03-2018 IPR001310 Histidine triad (HIT) protein SMALA_RS12930 410dd44b5941ead52041c8547a753d87 119 Gene3D G3DSA:3.30.428.10 2 112 7.3E-32 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 SMALA_RS12930 410dd44b5941ead52041c8547a753d87 119 SUPERFAMILY SSF54197 7 118 3.56E-34 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 SMALA_RS07035 9a802aa334e37a36930cd65cb42159fd 525 SUPERFAMILY SSF54373 292 473 6.57E-35 T 29-03-2018 SMALA_RS07035 9a802aa334e37a36930cd65cb42159fd 525 Pfam PF00732 GMC oxidoreductase 8 296 7.6E-83 T 29-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 SMALA_RS07035 9a802aa334e37a36930cd65cb42159fd 525 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 256 270 - T 29-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 SMALA_RS07035 9a802aa334e37a36930cd65cb42159fd 525 Gene3D G3DSA:4.10.450.10 43 106 6.6E-28 T 29-03-2018 SMALA_RS07035 9a802aa334e37a36930cd65cb42159fd 525 PIRSF PIRSF000137 1 525 3.3E-138 T 29-03-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 SMALA_RS07035 9a802aa334e37a36930cd65cb42159fd 525 SUPERFAMILY SSF51905 472 523 5.34E-84 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS07035 9a802aa334e37a36930cd65cb42159fd 525 SUPERFAMILY SSF51905 5 290 5.34E-84 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS07035 9a802aa334e37a36930cd65cb42159fd 525 ProSitePatterns PS00623 GMC oxidoreductases signature 1. 84 107 - T 29-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 SMALA_RS07035 9a802aa334e37a36930cd65cb42159fd 525 Pfam PF05199 GMC oxidoreductase 381 519 1.3E-38 T 29-03-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 SMALA_RS07035 9a802aa334e37a36930cd65cb42159fd 525 Gene3D G3DSA:3.30.560.10 107 487 2.7E-94 T 29-03-2018 SMALA_RS25560 f5811cb2f2b8dface4474bd3b04ead01 711 PIRSF PIRSF002741 528 697 3.7E-9 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 SMALA_RS25560 f5811cb2f2b8dface4474bd3b04ead01 711 PIRSF PIRSF002741 7 298 1.2E-20 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 SMALA_RS25560 f5811cb2f2b8dface4474bd3b04ead01 711 PIRSF PIRSF002741 321 450 4.6E-12 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 SMALA_RS25560 f5811cb2f2b8dface4474bd3b04ead01 711 Gene3D G3DSA:3.90.76.10 62 210 2.0E-19 T 29-03-2018 SMALA_RS25560 f5811cb2f2b8dface4474bd3b04ead01 711 SUPERFAMILY SSF53850 51 285 1.63E-49 T 29-03-2018 SMALA_RS25560 f5811cb2f2b8dface4474bd3b04ead01 711 SUPERFAMILY SSF53850 338 442 1.63E-49 T 29-03-2018 SMALA_RS25560 f5811cb2f2b8dface4474bd3b04ead01 711 Gene3D G3DSA:3.10.105.10 357 680 4.6E-80 T 29-03-2018 SMALA_RS25560 f5811cb2f2b8dface4474bd3b04ead01 711 SUPERFAMILY SSF53850 536 708 2.71E-21 T 29-03-2018 SMALA_RS25560 f5811cb2f2b8dface4474bd3b04ead01 711 Gene3D G3DSA:3.40.190.10 211 356 9.2E-30 T 29-03-2018 SMALA_RS25560 f5811cb2f2b8dface4474bd3b04ead01 711 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 105 464 1.6E-40 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain SMALA_RS41830 64c4461d6f9572a8ca9f3e196ce4d8e1 337 Gene3D G3DSA:1.20.1440.110 4 92 0.054 T 29-03-2018 SMALA_RS41830 64c4461d6f9572a8ca9f3e196ce4d8e1 337 SUPERFAMILY SSF53474 17 334 1.68E-31 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS41830 64c4461d6f9572a8ca9f3e196ce4d8e1 337 Gene3D G3DSA:3.40.50.1820 104 337 2.5E-21 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS20910 8c0f9a6d43fcd54785708b46174d49a4 749 Pfam PF02769 AIR synthase related protein, C-terminal domain 211 366 1.8E-33 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain SMALA_RS20910 8c0f9a6d43fcd54785708b46174d49a4 749 Pfam PF02769 AIR synthase related protein, C-terminal domain 585 722 1.7E-21 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain SMALA_RS20910 8c0f9a6d43fcd54785708b46174d49a4 749 Gene3D G3DSA:3.90.650.10 581 749 1.5E-38 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain SMALA_RS20910 8c0f9a6d43fcd54785708b46174d49a4 749 Gene3D G3DSA:3.30.1330.10 23 189 1.9E-54 T 29-03-2018 IPR016188 PurM-like, N-terminal domain SMALA_RS20910 8c0f9a6d43fcd54785708b46174d49a4 749 Gene3D G3DSA:3.30.1330.10 410 577 8.9E-45 T 29-03-2018 IPR016188 PurM-like, N-terminal domain SMALA_RS20910 8c0f9a6d43fcd54785708b46174d49a4 749 SUPERFAMILY SSF55326 19 204 1.79E-49 T 29-03-2018 IPR016188 PurM-like, N-terminal domain SMALA_RS20910 8c0f9a6d43fcd54785708b46174d49a4 749 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 1 749 313.853 T 29-03-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 SMALA_RS20910 8c0f9a6d43fcd54785708b46174d49a4 749 SUPERFAMILY SSF56042 209 439 2.39E-53 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain SMALA_RS20910 8c0f9a6d43fcd54785708b46174d49a4 749 SUPERFAMILY SSF55326 409 578 9.16E-55 T 29-03-2018 IPR016188 PurM-like, N-terminal domain SMALA_RS20910 8c0f9a6d43fcd54785708b46174d49a4 749 Gene3D G3DSA:3.90.650.10 190 381 3.0E-38 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain SMALA_RS20910 8c0f9a6d43fcd54785708b46174d49a4 749 SUPERFAMILY SSF56042 583 748 9.27E-41 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain SMALA_RS20910 8c0f9a6d43fcd54785708b46174d49a4 749 Pfam PF00586 AIR synthase related protein, N-terminal domain 468 572 6.1E-22 T 29-03-2018 IPR016188 PurM-like, N-terminal domain SMALA_RS20910 8c0f9a6d43fcd54785708b46174d49a4 749 Pfam PF00586 AIR synthase related protein, N-terminal domain 96 198 7.5E-23 T 29-03-2018 IPR016188 PurM-like, N-terminal domain SMALA_RS20910 8c0f9a6d43fcd54785708b46174d49a4 749 TIGRFAM TIGR01736 FGAM_synth_II: phosphoribosylformylglycinamidine synthase II 24 745 1.1E-264 T 29-03-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 SMALA_RS20910 8c0f9a6d43fcd54785708b46174d49a4 749 PIRSF PIRSF001587 5 749 4.2E-293 T 29-03-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 SMALA_RS39930 f56e25497a07f9e9df7857184cdd9b2e 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 170 189 8.9E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS39930 f56e25497a07f9e9df7857184cdd9b2e 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 92 103 8.9E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS39930 f56e25497a07f9e9df7857184cdd9b2e 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 157 8.9E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS39930 f56e25497a07f9e9df7857184cdd9b2e 267 SUPERFAMILY SSF51735 17 260 1.05E-77 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS39930 f56e25497a07f9e9df7857184cdd9b2e 267 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 157 185 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMALA_RS39930 f56e25497a07f9e9df7857184cdd9b2e 267 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 26 260 1.1E-57 T 29-03-2018 SMALA_RS39930 f56e25497a07f9e9df7857184cdd9b2e 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 224 244 3.0E-34 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS39930 f56e25497a07f9e9df7857184cdd9b2e 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 191 208 3.0E-34 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS39930 f56e25497a07f9e9df7857184cdd9b2e 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 189 3.0E-34 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS39930 f56e25497a07f9e9df7857184cdd9b2e 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 19 36 3.0E-34 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS39930 f56e25497a07f9e9df7857184cdd9b2e 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 92 103 3.0E-34 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS39930 f56e25497a07f9e9df7857184cdd9b2e 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 143 159 3.0E-34 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS39930 f56e25497a07f9e9df7857184cdd9b2e 267 Gene3D G3DSA:3.40.50.720 10 59 1.9E-10 T 29-03-2018 SMALA_RS39930 f56e25497a07f9e9df7857184cdd9b2e 267 Gene3D G3DSA:3.40.50.720 60 267 3.4E-59 T 29-03-2018 SMALA_RS10615 3322e86f66ce23a736e21737be3e5a5e 258 Pfam PF04012 PspA/IM30 family 2 228 1.5E-28 T 29-03-2018 IPR007157 PspA/IM30 SMALA_RS10615 3322e86f66ce23a736e21737be3e5a5e 258 Gene3D G3DSA:1.20.5.400 80 149 4.4E-5 T 29-03-2018 SMALA_RS27130 82d1abffc883e28a48b4150ad1a3fcb8 225 Gene3D G3DSA:1.10.357.10 67 215 4.7E-25 T 29-03-2018 SMALA_RS27130 82d1abffc883e28a48b4150ad1a3fcb8 225 SUPERFAMILY SSF48498 81 200 1.33E-14 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS27130 82d1abffc883e28a48b4150ad1a3fcb8 225 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 64 2.1E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS27130 82d1abffc883e28a48b4150ad1a3fcb8 225 Pfam PF16859 Bacterial transcriptional repressor C-terminal 78 195 8.3E-17 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS27130 82d1abffc883e28a48b4150ad1a3fcb8 225 Gene3D G3DSA:1.10.10.60 1 66 3.9E-16 T 29-03-2018 SMALA_RS27130 82d1abffc883e28a48b4150ad1a3fcb8 225 SUPERFAMILY SSF46689 10 78 1.25E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS27130 82d1abffc883e28a48b4150ad1a3fcb8 225 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 2.1E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS27130 82d1abffc883e28a48b4150ad1a3fcb8 225 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 2.1E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS27435 550469cd021c8c6a631d66d6d35e53d2 792 TIGRFAM TIGR02100 glgX_debranch: glycogen debranching enzyme GlgX 69 780 7.0E-301 T 29-03-2018 IPR011837 Glycogen debranching enzyme, GlgX type GO:0004133|GO:0004553|GO:0005980 SMALA_RS27435 550469cd021c8c6a631d66d6d35e53d2 792 Gene3D G3DSA:2.60.40.1180 662 784 1.4E-27 T 29-03-2018 SMALA_RS27435 550469cd021c8c6a631d66d6d35e53d2 792 SMART SM00642 238 649 4.0E-8 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SMALA_RS27435 550469cd021c8c6a631d66d6d35e53d2 792 Gene3D G3DSA:3.20.20.80 220 661 9.8E-114 T 29-03-2018 SMALA_RS27435 550469cd021c8c6a631d66d6d35e53d2 792 SUPERFAMILY SSF81296 68 211 1.0E-36 T 29-03-2018 IPR014756 Immunoglobulin E-set SMALA_RS27435 550469cd021c8c6a631d66d6d35e53d2 792 SUPERFAMILY SSF51445 217 550 1.13E-133 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS27435 550469cd021c8c6a631d66d6d35e53d2 792 SUPERFAMILY SSF51445 579 657 1.13E-133 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS27435 550469cd021c8c6a631d66d6d35e53d2 792 SUPERFAMILY SSF51011 670 781 1.94E-17 T 29-03-2018 SMALA_RS27435 550469cd021c8c6a631d66d6d35e53d2 792 Gene3D G3DSA:2.60.40.10 69 210 1.4E-46 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS27435 550469cd021c8c6a631d66d6d35e53d2 792 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 73 164 2.2E-19 T 29-03-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077 SMALA_RS27435 550469cd021c8c6a631d66d6d35e53d2 792 Pfam PF00128 Alpha amylase, catalytic domain 268 358 7.0E-6 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SMALA_RS02015 6a2280ff4191dbe46146d8b3898a30c8 238 Pfam PF00196 Bacterial regulatory proteins, luxR family 168 223 3.1E-17 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS02015 6a2280ff4191dbe46146d8b3898a30c8 238 Gene3D G3DSA:1.10.10.10 130 233 1.0E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS02015 6a2280ff4191dbe46146d8b3898a30c8 238 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 199 211 4.6E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS02015 6a2280ff4191dbe46146d8b3898a30c8 238 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 183 4.6E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS02015 6a2280ff4191dbe46146d8b3898a30c8 238 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 183 199 4.6E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS02015 6a2280ff4191dbe46146d8b3898a30c8 238 SMART SM00421 166 223 4.6E-21 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS02015 6a2280ff4191dbe46146d8b3898a30c8 238 Pfam PF00072 Response regulator receiver domain 5 118 9.3E-23 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS02015 6a2280ff4191dbe46146d8b3898a30c8 238 SUPERFAMILY SSF46894 164 230 7.82E-20 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS02015 6a2280ff4191dbe46146d8b3898a30c8 238 ProSitePatterns PS00622 LuxR-type HTH domain signature. 183 210 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS02015 6a2280ff4191dbe46146d8b3898a30c8 238 SUPERFAMILY SSF52172 2 132 3.7E-29 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS02015 6a2280ff4191dbe46146d8b3898a30c8 238 Gene3D G3DSA:3.40.50.2300 2 129 6.8E-29 T 29-03-2018 SMALA_RS02015 6a2280ff4191dbe46146d8b3898a30c8 238 SMART SM00448 3 118 1.7E-23 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS09640 0b9e58d051183bd0d2416c4c48d1b116 436 Gene3D G3DSA:1.20.1250.20 2 212 1.4E-25 T 29-03-2018 SMALA_RS09640 0b9e58d051183bd0d2416c4c48d1b116 436 Pfam PF07690 Major Facilitator Superfamily 268 424 2.6E-10 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS09640 0b9e58d051183bd0d2416c4c48d1b116 436 Pfam PF00083 Sugar (and other) transporter 7 222 2.3E-26 T 29-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 SMALA_RS09640 0b9e58d051183bd0d2416c4c48d1b116 436 ProSitePatterns PS00217 Sugar transport proteins signature 2. 115 140 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMALA_RS09640 0b9e58d051183bd0d2416c4c48d1b116 436 SUPERFAMILY SSF103473 3 414 1.26E-59 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS09640 0b9e58d051183bd0d2416c4c48d1b116 436 Gene3D G3DSA:1.20.1250.20 213 418 4.0E-22 T 29-03-2018 SMALA_RS17060 a1073a1860e041f4ba66b4819c57cee2 567 Gene3D G3DSA:3.30.200.20 3 99 1.5E-22 T 29-03-2018 SMALA_RS17060 a1073a1860e041f4ba66b4819c57cee2 567 Pfam PF00069 Protein kinase domain 15 265 2.4E-50 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMALA_RS17060 a1073a1860e041f4ba66b4819c57cee2 567 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 20 43 - T 29-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 SMALA_RS17060 a1073a1860e041f4ba66b4819c57cee2 567 Gene3D G3DSA:1.10.510.10 100 409 1.3E-46 T 29-03-2018 SMALA_RS17060 a1073a1860e041f4ba66b4819c57cee2 567 SUPERFAMILY SSF56112 7 325 1.89E-69 T 29-03-2018 IPR011009 Protein kinase-like domain SMALA_RS17060 a1073a1860e041f4ba66b4819c57cee2 567 SMART SM00220 14 271 5.3E-62 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMALA_RS17060 a1073a1860e041f4ba66b4819c57cee2 567 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 137 149 - T 29-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMALA_RS17060 a1073a1860e041f4ba66b4819c57cee2 567 Gene3D G3DSA:3.40.1000.10 429 561 4.9E-8 T 29-03-2018 SMALA_RS29895 ba06fdecc498bf82cf9353d7836a4fbf 611 Gene3D G3DSA:3.40.50.1820 145 572 1.8E-36 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS29895 ba06fdecc498bf82cf9353d7836a4fbf 611 Pfam PF08386 TAP-like protein 477 582 8.8E-24 T 29-03-2018 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal SMALA_RS29895 ba06fdecc498bf82cf9353d7836a4fbf 611 SUPERFAMILY SSF53474 264 318 1.58E-21 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS29895 ba06fdecc498bf82cf9353d7836a4fbf 611 SUPERFAMILY SSF53474 468 570 1.58E-21 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS29895 ba06fdecc498bf82cf9353d7836a4fbf 611 SUPERFAMILY SSF53474 160 219 1.58E-21 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS13110 1478c7276fb7a4a06e47c40f62a0ee78 389 PRINTS PR00474 Glutamate 5-kinase family signature 65 79 5.6E-54 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 SMALA_RS13110 1478c7276fb7a4a06e47c40f62a0ee78 389 PRINTS PR00474 Glutamate 5-kinase family signature 232 252 5.6E-54 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 SMALA_RS13110 1478c7276fb7a4a06e47c40f62a0ee78 389 PRINTS PR00474 Glutamate 5-kinase family signature 139 160 5.6E-54 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 SMALA_RS13110 1478c7276fb7a4a06e47c40f62a0ee78 389 PRINTS PR00474 Glutamate 5-kinase family signature 171 198 5.6E-54 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 SMALA_RS13110 1478c7276fb7a4a06e47c40f62a0ee78 389 PRINTS PR00474 Glutamate 5-kinase family signature 99 127 5.6E-54 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 SMALA_RS13110 1478c7276fb7a4a06e47c40f62a0ee78 389 Pfam PF01472 PUA domain 297 370 7.1E-18 T 29-03-2018 IPR002478 PUA domain GO:0003723 SMALA_RS13110 1478c7276fb7a4a06e47c40f62a0ee78 389 SUPERFAMILY SSF88697 297 387 9.94E-22 T 29-03-2018 IPR015947 PUA-like domain SMALA_RS13110 1478c7276fb7a4a06e47c40f62a0ee78 389 Hamap MF_00456 Glutamate 5-kinase [proB]. 5 279 35.442 T 29-03-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 SMALA_RS13110 1478c7276fb7a4a06e47c40f62a0ee78 389 Gene3D G3DSA:3.40.1160.10 1 285 2.9E-59 T 29-03-2018 SMALA_RS13110 1478c7276fb7a4a06e47c40f62a0ee78 389 SMART SM00359 297 376 1.2E-14 T 29-03-2018 IPR002478 PUA domain GO:0003723 SMALA_RS13110 1478c7276fb7a4a06e47c40f62a0ee78 389 PIRSF PIRSF000729 1 44 3.2E-5 T 29-03-2018 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 SMALA_RS13110 1478c7276fb7a4a06e47c40f62a0ee78 389 PIRSF PIRSF000729 60 389 1.2E-110 T 29-03-2018 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 SMALA_RS13110 1478c7276fb7a4a06e47c40f62a0ee78 389 Gene3D G3DSA:2.30.130.10 295 387 1.4E-27 T 29-03-2018 IPR002478 PUA domain GO:0003723 SMALA_RS13110 1478c7276fb7a4a06e47c40f62a0ee78 389 TIGRFAM TIGR01027 proB: glutamate 5-kinase 64 386 3.0E-118 T 29-03-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 SMALA_RS13110 1478c7276fb7a4a06e47c40f62a0ee78 389 Pfam PF00696 Amino acid kinase family 6 258 2.4E-38 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase SMALA_RS13110 1478c7276fb7a4a06e47c40f62a0ee78 389 SUPERFAMILY SSF53633 5 276 2.3E-57 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase SMALA_RS13110 1478c7276fb7a4a06e47c40f62a0ee78 389 ProSitePatterns PS00902 Glutamate 5-kinase signature. 230 247 - T 29-03-2018 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 SMALA_RS14355 588cc1a49fc3a8d6e2399f98a2c08fad 297 SUPERFAMILY SSF50129 1 142 2.43E-29 T 29-03-2018 IPR011032 GroES-like SMALA_RS14355 588cc1a49fc3a8d6e2399f98a2c08fad 297 Gene3D G3DSA:3.90.180.10 1 145 2.2E-40 T 29-03-2018 SMALA_RS14355 588cc1a49fc3a8d6e2399f98a2c08fad 297 Gene3D G3DSA:3.90.180.10 146 296 7.5E-14 T 29-03-2018 SMALA_RS14355 588cc1a49fc3a8d6e2399f98a2c08fad 297 Pfam PF13602 Zinc-binding dehydrogenase 189 295 1.5E-11 T 29-03-2018 SMALA_RS14355 588cc1a49fc3a8d6e2399f98a2c08fad 297 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 91 4.2E-9 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS14355 588cc1a49fc3a8d6e2399f98a2c08fad 297 SMART SM00829 10 295 1.8E-12 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS14355 588cc1a49fc3a8d6e2399f98a2c08fad 297 SUPERFAMILY SSF51735 111 233 1.22E-22 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS14355 588cc1a49fc3a8d6e2399f98a2c08fad 297 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 138 159 - T 29-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 SMALA_RS05820 aeb4b16847517669f3106ee2f4f27b80 1137 Gene3D G3DSA:2.160.20.10 711 1134 1.3E-48 T 29-03-2018 IPR012334 Pectin lyase fold SMALA_RS05820 aeb4b16847517669f3106ee2f4f27b80 1137 Gene3D G3DSA:2.60.120.260 177 324 1.3E-21 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS05820 aeb4b16847517669f3106ee2f4f27b80 1137 Pfam PF00754 F5/8 type C domain 196 319 3.2E-9 T 29-03-2018 IPR000421 Coagulation factor 5/8 C-terminal domain SMALA_RS05820 aeb4b16847517669f3106ee2f4f27b80 1137 Pfam PF00754 F5/8 type C domain 49 169 2.8E-22 T 29-03-2018 IPR000421 Coagulation factor 5/8 C-terminal domain SMALA_RS05820 aeb4b16847517669f3106ee2f4f27b80 1137 SUPERFAMILY SSF51126 1045 1113 4.26E-5 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor SMALA_RS05820 aeb4b16847517669f3106ee2f4f27b80 1137 Gene3D G3DSA:2.60.40.10 325 430 9.0E-19 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS05820 aeb4b16847517669f3106ee2f4f27b80 1137 Gene3D G3DSA:2.60.40.10 431 549 2.2E-17 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS05820 aeb4b16847517669f3106ee2f4f27b80 1137 SUPERFAMILY SSF49785 41 175 1.21E-26 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS05820 aeb4b16847517669f3106ee2f4f27b80 1137 SMART SM00710 1097 1118 6100.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat SMALA_RS05820 aeb4b16847517669f3106ee2f4f27b80 1137 SMART SM00710 895 917 89.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat SMALA_RS05820 aeb4b16847517669f3106ee2f4f27b80 1137 SMART SM00710 1071 1094 580.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat SMALA_RS05820 aeb4b16847517669f3106ee2f4f27b80 1137 SMART SM00710 1044 1066 1.9 T 29-03-2018 IPR006626 Parallel beta-helix repeat SMALA_RS05820 aeb4b16847517669f3106ee2f4f27b80 1137 SMART SM00710 828 859 6800.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat SMALA_RS05820 aeb4b16847517669f3106ee2f4f27b80 1137 SMART SM00710 862 883 1900.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat SMALA_RS05820 aeb4b16847517669f3106ee2f4f27b80 1137 SMART SM00710 977 1000 140.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat SMALA_RS05820 aeb4b16847517669f3106ee2f4f27b80 1137 SMART SM00710 953 976 98.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat SMALA_RS05820 aeb4b16847517669f3106ee2f4f27b80 1137 SMART SM00710 919 941 230.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat SMALA_RS05820 aeb4b16847517669f3106ee2f4f27b80 1137 Gene3D G3DSA:2.60.120.260 550 710 5.2E-9 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS05820 aeb4b16847517669f3106ee2f4f27b80 1137 SMART SM00231 40 175 4.3E-6 T 29-03-2018 IPR000421 Coagulation factor 5/8 C-terminal domain SMALA_RS05820 aeb4b16847517669f3106ee2f4f27b80 1137 Gene3D G3DSA:2.60.120.260 31 176 2.9E-34 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS05820 aeb4b16847517669f3106ee2f4f27b80 1137 SUPERFAMILY SSF49785 185 323 2.34E-16 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS05820 aeb4b16847517669f3106ee2f4f27b80 1137 SUPERFAMILY SSF51126 706 1023 9.26E-37 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor SMALA_RS05820 aeb4b16847517669f3106ee2f4f27b80 1137 Pfam PF07705 CARDB 441 541 1.8E-15 T 29-03-2018 IPR011635 CARDB domain SMALA_RS05820 aeb4b16847517669f3106ee2f4f27b80 1137 Pfam PF07705 CARDB 328 427 3.2E-21 T 29-03-2018 IPR011635 CARDB domain SMALA_RS01560 b4d0c8a085bf4ada9f74d0892c503f5c 2378 SUPERFAMILY SSF51735 1894 2070 1.98E-8 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS01560 b4d0c8a085bf4ada9f74d0892c503f5c 2378 Gene3D G3DSA:1.10.1200.10 1750 1841 1.0E-14 T 29-03-2018 SMALA_RS01560 b4d0c8a085bf4ada9f74d0892c503f5c 2378 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 696 967 2.3E-66 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS01560 b4d0c8a085bf4ada9f74d0892c503f5c 2378 Gene3D G3DSA:3.20.20.70 6 291 4.3E-12 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS01560 b4d0c8a085bf4ada9f74d0892c503f5c 2378 Gene3D G3DSA:3.40.366.10 1271 1415 6.8E-26 T 29-03-2018 SMALA_RS01560 b4d0c8a085bf4ada9f74d0892c503f5c 2378 Gene3D G3DSA:3.30.70.250 1416 1461 1.5E-16 T 29-03-2018 SMALA_RS01560 b4d0c8a085bf4ada9f74d0892c503f5c 2378 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1103 1183 2.3E-7 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS01560 b4d0c8a085bf4ada9f74d0892c503f5c 2378 SMART SM00825 Beta-ketoacyl synthase 697 1145 2.7E-111 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS01560 b4d0c8a085bf4ada9f74d0892c503f5c 2378 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2101 2325 5.6E-28 T 29-03-2018 SMALA_RS01560 b4d0c8a085bf4ada9f74d0892c503f5c 2378 SUPERFAMILY SSF47336 1747 1848 7.34E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS01560 b4d0c8a085bf4ada9f74d0892c503f5c 2378 SUPERFAMILY SSF52151 1471 1571 3.4E-49 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS01560 b4d0c8a085bf4ada9f74d0892c503f5c 2378 SUPERFAMILY SSF52151 1271 1400 3.4E-49 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS01560 b4d0c8a085bf4ada9f74d0892c503f5c 2378 SUPERFAMILY SSF51412 98 222 2.2E-13 T 29-03-2018 SMALA_RS01560 b4d0c8a085bf4ada9f74d0892c503f5c 2378 SUPERFAMILY SSF51412 20 71 2.2E-13 T 29-03-2018 SMALA_RS01560 b4d0c8a085bf4ada9f74d0892c503f5c 2378 Gene3D G3DSA:3.40.50.720 1885 2058 0.0045 T 29-03-2018 SMALA_RS01560 b4d0c8a085bf4ada9f74d0892c503f5c 2378 Pfam PF03060 Nitronate monooxygenase 117 217 1.0E-6 T 29-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 SMALA_RS01560 b4d0c8a085bf4ada9f74d0892c503f5c 2378 Pfam PF03060 Nitronate monooxygenase 303 583 5.2E-8 T 29-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 SMALA_RS01560 b4d0c8a085bf4ada9f74d0892c503f5c 2378 SUPERFAMILY SSF53901 693 820 1.1E-73 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS01560 b4d0c8a085bf4ada9f74d0892c503f5c 2378 SUPERFAMILY SSF53901 1121 1135 1.1E-73 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS01560 b4d0c8a085bf4ada9f74d0892c503f5c 2378 SUPERFAMILY SSF53901 863 1088 1.1E-73 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS01560 b4d0c8a085bf4ada9f74d0892c503f5c 2378 Pfam PF00698 Acyl transferase domain 1274 1596 1.1E-32 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS01560 b4d0c8a085bf4ada9f74d0892c503f5c 2378 Gene3D G3DSA:3.40.47.10 982 1143 2.8E-52 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS01560 b4d0c8a085bf4ada9f74d0892c503f5c 2378 Pfam PF08659 KR domain 2102 2323 7.5E-36 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS01560 b4d0c8a085bf4ada9f74d0892c503f5c 2378 Gene3D G3DSA:3.40.366.10 1462 1579 2.6E-25 T 29-03-2018 SMALA_RS01560 b4d0c8a085bf4ada9f74d0892c503f5c 2378 SUPERFAMILY SSF51735 2184 2359 1.57E-30 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS01560 b4d0c8a085bf4ada9f74d0892c503f5c 2378 SUPERFAMILY SSF51735 2099 2139 1.57E-30 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS01560 b4d0c8a085bf4ada9f74d0892c503f5c 2378 Gene3D G3DSA:3.20.20.70 292 690 3.3E-14 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS01560 b4d0c8a085bf4ada9f74d0892c503f5c 2378 Gene3D G3DSA:3.40.47.10 698 980 1.2E-72 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS01560 b4d0c8a085bf4ada9f74d0892c503f5c 2378 SUPERFAMILY SSF55048 1404 1469 7.59E-13 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS01560 b4d0c8a085bf4ada9f74d0892c503f5c 2378 Gene3D G3DSA:3.40.50.720 2094 2376 1.1E-38 T 29-03-2018 SMALA_RS01560 b4d0c8a085bf4ada9f74d0892c503f5c 2378 SUPERFAMILY SSF51412 302 581 2.5E-11 T 29-03-2018 SMALA_RS01560 b4d0c8a085bf4ada9f74d0892c503f5c 2378 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1275 1578 2.1E-27 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS01560 b4d0c8a085bf4ada9f74d0892c503f5c 2378 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 975 1092 1.3E-37 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS01560 b4d0c8a085bf4ada9f74d0892c503f5c 2378 Pfam PF00550 Phosphopantetheine attachment site 1755 1819 2.9E-6 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS37370 e2e9fbf0bd6aac98848833f667fc1a4b 208 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 47 78 - T 29-03-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS37370 e2e9fbf0bd6aac98848833f667fc1a4b 208 Pfam PF08281 Sigma-70, region 4 123 173 3.0E-13 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS37370 e2e9fbf0bd6aac98848833f667fc1a4b 208 Gene3D G3DSA:1.10.1740.10 1 113 4.6E-25 T 29-03-2018 SMALA_RS37370 e2e9fbf0bd6aac98848833f667fc1a4b 208 SUPERFAMILY SSF88946 3 99 3.92E-24 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS37370 e2e9fbf0bd6aac98848833f667fc1a4b 208 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 21 174 5.3E-22 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS37370 e2e9fbf0bd6aac98848833f667fc1a4b 208 Pfam PF04542 Sigma-70 region 2 25 88 4.8E-17 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS37370 e2e9fbf0bd6aac98848833f667fc1a4b 208 Gene3D G3DSA:1.10.10.10 121 206 1.3E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS37370 e2e9fbf0bd6aac98848833f667fc1a4b 208 SUPERFAMILY SSF88659 117 175 2.03E-12 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS32075 c3f25e4c12d527b03f7a71b062e06083 283 ProSitePatterns PS00211 ABC transporters family signature. 187 201 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS32075 c3f25e4c12d527b03f7a71b062e06083 283 Gene3D G3DSA:3.40.50.300 33 283 4.2E-44 T 29-03-2018 SMALA_RS32075 c3f25e4c12d527b03f7a71b062e06083 283 SMART SM00382 89 263 1.3E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS32075 c3f25e4c12d527b03f7a71b062e06083 283 Pfam PF00005 ABC transporter 81 214 1.0E-14 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS32075 c3f25e4c12d527b03f7a71b062e06083 283 SUPERFAMILY SSF52540 75 277 6.61E-40 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS12955 b2674200844d57ae2738476686d69818 338 PIRSF PIRSF005485 1 338 1.1E-101 T 29-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 SMALA_RS12955 b2674200844d57ae2738476686d69818 338 Gene3D G3DSA:3.30.450.40 187 338 4.6E-39 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS12955 b2674200844d57ae2738476686d69818 338 TIGRFAM TIGR00331 hrcA: heat-inducible transcription repressor HrcA 3 334 1.6E-102 T 29-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 SMALA_RS12955 b2674200844d57ae2738476686d69818 338 SUPERFAMILY SSF46785 2 82 1.6E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS12955 b2674200844d57ae2738476686d69818 338 Gene3D G3DSA:1.10.10.10 1 84 3.0E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS12955 b2674200844d57ae2738476686d69818 338 SUPERFAMILY SSF55781 71 336 3.33E-57 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS12955 b2674200844d57ae2738476686d69818 338 Pfam PF01628 HrcA protein C terminal domain 103 321 4.5E-63 T 29-03-2018 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 SMALA_RS12955 b2674200844d57ae2738476686d69818 338 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 1 328 28.66 T 29-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 SMALA_RS38550 2afe9ba8ec27ccf232001b55bb1c61af 454 Gene3D G3DSA:1.20.1250.20 237 454 3.1E-29 T 29-03-2018 SMALA_RS38550 2afe9ba8ec27ccf232001b55bb1c61af 454 ProSitePatterns PS00217 Sugar transport proteins signature 2. 128 153 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMALA_RS38550 2afe9ba8ec27ccf232001b55bb1c61af 454 Pfam PF00083 Sugar (and other) transporter 58 444 1.5E-56 T 29-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 SMALA_RS38550 2afe9ba8ec27ccf232001b55bb1c61af 454 Gene3D G3DSA:1.20.1250.20 35 223 2.0E-34 T 29-03-2018 SMALA_RS38550 2afe9ba8ec27ccf232001b55bb1c61af 454 SUPERFAMILY SSF103473 15 443 5.49E-76 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS19850 8003667ec31370bd1d0833cddd64135a 490 SUPERFAMILY SSF56601 139 486 2.65E-85 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMALA_RS19850 8003667ec31370bd1d0833cddd64135a 490 Pfam PF00905 Penicillin binding protein transpeptidase domain 156 481 4.5E-71 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 SMALA_RS19850 8003667ec31370bd1d0833cddd64135a 490 Gene3D G3DSA:3.90.1310.10 17 140 2.5E-20 T 29-03-2018 SMALA_RS19850 8003667ec31370bd1d0833cddd64135a 490 Gene3D G3DSA:3.40.710.10 141 490 2.6E-90 T 29-03-2018 SMALA_RS33975 2786df76e776779a500faf21c0fb08af 644 Gene3D G3DSA:2.60.40.1180 578 643 0.0049 T 29-03-2018 SMALA_RS33975 2786df76e776779a500faf21c0fb08af 644 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 35 294 4.5E-11 T 29-03-2018 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 SMALA_RS33975 2786df76e776779a500faf21c0fb08af 644 Gene3D G3DSA:3.20.20.80 173 346 1.0E-15 T 29-03-2018 SMALA_RS33975 2786df76e776779a500faf21c0fb08af 644 Gene3D G3DSA:3.20.20.80 26 172 1.4E-16 T 29-03-2018 SMALA_RS33975 2786df76e776779a500faf21c0fb08af 644 Gene3D G3DSA:3.40.50.880 347 577 4.7E-14 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS33975 2786df76e776779a500faf21c0fb08af 644 SUPERFAMILY SSF51445 17 332 6.63E-43 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS34805 97907ca4b8675d5be8143af3948f52bd 574 SUPERFAMILY SSF51556 488 574 1.02E-186 T 29-03-2018 IPR032466 Metal-dependent hydrolase SMALA_RS34805 97907ca4b8675d5be8143af3948f52bd 574 SUPERFAMILY SSF51556 137 439 1.02E-186 T 29-03-2018 IPR032466 Metal-dependent hydrolase SMALA_RS34805 97907ca4b8675d5be8143af3948f52bd 574 Pfam PF01979 Amidohydrolase family 133 459 1.5E-68 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 SMALA_RS34805 97907ca4b8675d5be8143af3948f52bd 574 Gene3D G3DSA:2.30.40.10 58 149 2.5E-15 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS34805 97907ca4b8675d5be8143af3948f52bd 574 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 303 320 1.4E-32 T 29-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMALA_RS34805 97907ca4b8675d5be8143af3948f52bd 574 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 434 447 1.4E-32 T 29-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMALA_RS34805 97907ca4b8675d5be8143af3948f52bd 574 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 342 358 1.4E-32 T 29-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMALA_RS34805 97907ca4b8675d5be8143af3948f52bd 574 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 408 423 1.4E-32 T 29-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMALA_RS34805 97907ca4b8675d5be8143af3948f52bd 574 SUPERFAMILY SSF51338 416 486 3.65E-11 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS34805 97907ca4b8675d5be8143af3948f52bd 574 SUPERFAMILY SSF51338 3 185 9.91E-58 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS34805 97907ca4b8675d5be8143af3948f52bd 574 Gene3D G3DSA:3.20.20.140 429 560 4.0E-45 T 29-03-2018 SMALA_RS34805 97907ca4b8675d5be8143af3948f52bd 574 Gene3D G3DSA:3.20.20.140 150 428 5.5E-153 T 29-03-2018 SMALA_RS34805 97907ca4b8675d5be8143af3948f52bd 574 ProSitePatterns PS00145 Urease active site. 325 341 - T 29-03-2018 IPR017950 Urease active site GO:0009039 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMALA_RS34805 97907ca4b8675d5be8143af3948f52bd 574 TIGRFAM TIGR01792 urease_alph: urease, alpha subunit 5 574 8.3E-271 T 29-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMALA_RS34805 97907ca4b8675d5be8143af3948f52bd 574 ProSitePatterns PS01120 Urease nickel ligands signature. 135 148 - T 29-03-2018 IPR029754 Urease nickel binding site GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMALA_RS34805 97907ca4b8675d5be8143af3948f52bd 574 Hamap MF_01953 Urease subunit alpha [ureC]. 3 574 55.79 T 29-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMALA_RS34805 97907ca4b8675d5be8143af3948f52bd 574 Pfam PF00449 Urease alpha-subunit, N-terminal domain 4 127 1.8E-53 T 29-03-2018 IPR011612 Urease alpha-subunit, N-terminal domain KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMALA_RS39085 d3d962b66729f413a7c279771c264967 357 PIRSF PIRSF000451 1 357 1.5E-95 T 29-03-2018 IPR011141 Polyketide synthase, type III GO:0009058|GO:0016747 SMALA_RS39085 d3d962b66729f413a7c279771c264967 357 Gene3D G3DSA:3.40.47.10 211 357 5.5E-34 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS39085 d3d962b66729f413a7c279771c264967 357 SUPERFAMILY SSF53901 11 357 4.21E-44 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS39085 d3d962b66729f413a7c279771c264967 357 Gene3D G3DSA:3.40.47.10 3 203 7.0E-21 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS39085 d3d962b66729f413a7c279771c264967 357 Pfam PF00195 Chalcone and stilbene synthases, N-terminal domain 76 200 7.7E-16 T 29-03-2018 IPR001099 Chalcone/stilbene synthase, N-terminal SMALA_RS39085 d3d962b66729f413a7c279771c264967 357 Pfam PF02797 Chalcone and stilbene synthases, C-terminal domain 241 355 8.4E-19 T 29-03-2018 IPR012328 Chalcone/stilbene synthase, C-terminal SMALA_RS15360 e6cf3fb3c8d3a06b699ce736e76cc4d7 93 SMART SM00411 1 91 6.8E-37 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 SMALA_RS15360 e6cf3fb3c8d3a06b699ce736e76cc4d7 93 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 47 66 - T 29-03-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 SMALA_RS15360 e6cf3fb3c8d3a06b699ce736e76cc4d7 93 Gene3D G3DSA:4.10.520.10 1 93 5.3E-29 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 SMALA_RS15360 e6cf3fb3c8d3a06b699ce736e76cc4d7 93 Pfam PF00216 Bacterial DNA-binding protein 1 90 1.3E-27 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 SMALA_RS15360 e6cf3fb3c8d3a06b699ce736e76cc4d7 93 SUPERFAMILY SSF47729 1 91 4.86E-26 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 SMALA_RS15360 e6cf3fb3c8d3a06b699ce736e76cc4d7 93 PRINTS PR01727 Prokaryotic integration host factor signature 59 72 1.8E-8 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 SMALA_RS15360 e6cf3fb3c8d3a06b699ce736e76cc4d7 93 PRINTS PR01727 Prokaryotic integration host factor signature 41 56 1.8E-8 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 SMALA_RS15360 e6cf3fb3c8d3a06b699ce736e76cc4d7 93 PRINTS PR01727 Prokaryotic integration host factor signature 75 89 1.8E-8 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 SMALA_RS09270 e1969cc1cea9d2a0aa03724820a57c65 256 Pfam PF01614 Bacterial transcriptional regulator 133 244 1.6E-28 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal SMALA_RS09270 e1969cc1cea9d2a0aa03724820a57c65 256 Gene3D G3DSA:1.10.10.10 1 72 2.8E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS09270 e1969cc1cea9d2a0aa03724820a57c65 256 SUPERFAMILY SSF55781 78 251 2.49E-46 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS09270 e1969cc1cea9d2a0aa03724820a57c65 256 SUPERFAMILY SSF46785 11 83 2.13E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS09270 e1969cc1cea9d2a0aa03724820a57c65 256 Gene3D G3DSA:3.30.450.40 76 253 2.7E-46 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS09270 e1969cc1cea9d2a0aa03724820a57c65 256 SMART SM00346 11 101 3.0E-19 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMALA_RS09270 e1969cc1cea9d2a0aa03724820a57c65 256 Pfam PF09339 IclR helix-turn-helix domain 13 63 1.7E-13 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMALA_RS30345 a57aee999fe619935b7a6446a6b70a3f 375 Gene3D G3DSA:1.10.40.50 278 344 4.7E-21 T 29-03-2018 SMALA_RS30345 a57aee999fe619935b7a6446a6b70a3f 375 Gene3D G3DSA:3.40.50.300 113 275 2.8E-25 T 29-03-2018 SMALA_RS30345 a57aee999fe619935b7a6446a6b70a3f 375 SUPERFAMILY SSF52540 118 337 7.37E-47 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS30345 a57aee999fe619935b7a6446a6b70a3f 375 Pfam PF03193 RsgA GTPase 100 276 1.1E-45 T 29-03-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 SMALA_RS30345 a57aee999fe619935b7a6446a6b70a3f 375 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 97 332 1.0E-47 T 29-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 SMALA_RS30345 a57aee999fe619935b7a6446a6b70a3f 375 Hamap MF_01820 Putative ribosome biogenesis GTPase RsgA [rsgA]. 42 339 31.314 T 29-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 SMALA_RS37460 bed20dfd0618d22f3f9c2ff3891aaaed 450 SUPERFAMILY SSF56762 5 441 6.54E-79 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS37460 bed20dfd0618d22f3f9c2ff3891aaaed 450 Gene3D G3DSA:1.10.645.10 2 236 6.3E-45 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS37460 bed20dfd0618d22f3f9c2ff3891aaaed 450 Pfam PF00374 Nickel-dependent hydrogenase 44 129 8.2E-10 T 29-03-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 SMALA_RS37460 bed20dfd0618d22f3f9c2ff3891aaaed 450 Gene3D G3DSA:1.10.645.10 237 441 1.5E-28 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS02980 40f015fb1c92366ca48cd9c4ca874f9c 119 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 77 92 4.9E-13 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS02980 40f015fb1c92366ca48cd9c4ca874f9c 119 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 30 45 4.9E-13 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS02980 40f015fb1c92366ca48cd9c4ca874f9c 119 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 62 77 4.9E-13 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS02980 40f015fb1c92366ca48cd9c4ca874f9c 119 Gene3D G3DSA:1.10.10.10 3 114 2.2E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS02980 40f015fb1c92366ca48cd9c4ca874f9c 119 SMART SM00418 28 106 1.5E-21 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS02980 40f015fb1c92366ca48cd9c4ca874f9c 119 SUPERFAMILY SSF46785 17 104 2.03E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS02980 40f015fb1c92366ca48cd9c4ca874f9c 119 Pfam PF01022 Bacterial regulatory protein, arsR family 35 80 3.3E-11 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS40640 538858ad2806957858c0a21d39483f2c 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 224 244 2.8E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40640 538858ad2806957858c0a21d39483f2c 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 2.8E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40640 538858ad2806957858c0a21d39483f2c 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 2.8E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40640 538858ad2806957858c0a21d39483f2c 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 2.8E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40640 538858ad2806957858c0a21d39483f2c 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 2.8E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40640 538858ad2806957858c0a21d39483f2c 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 2.8E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40640 538858ad2806957858c0a21d39483f2c 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 8.7E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40640 538858ad2806957858c0a21d39483f2c 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 8.7E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40640 538858ad2806957858c0a21d39483f2c 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 8.7E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40640 538858ad2806957858c0a21d39483f2c 264 Pfam PF00106 short chain dehydrogenase 10 197 1.2E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40640 538858ad2806957858c0a21d39483f2c 264 Gene3D G3DSA:3.40.50.720 1 262 3.3E-62 T 29-03-2018 SMALA_RS40640 538858ad2806957858c0a21d39483f2c 264 SUPERFAMILY SSF51735 7 261 6.87E-65 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS40640 538858ad2806957858c0a21d39483f2c 264 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMALA_RS11835 00c1ffb576a3fb8b7c7c70e9e2d3db14 189 Pfam PF00733 Asparagine synthase 42 169 7.4E-15 T 29-03-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 SMALA_RS11835 00c1ffb576a3fb8b7c7c70e9e2d3db14 189 SUPERFAMILY SSF52402 41 149 1.4E-7 T 29-03-2018 SMALA_RS11835 00c1ffb576a3fb8b7c7c70e9e2d3db14 189 Gene3D G3DSA:3.40.50.620 15 176 2.3E-15 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS11480 983ad6af91b49d3e142b6282292b67f0 543 SUPERFAMILY SSF52540 276 510 1.36E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS11480 983ad6af91b49d3e142b6282292b67f0 543 Gene3D G3DSA:3.40.50.300 1 233 6.7E-59 T 29-03-2018 SMALA_RS11480 983ad6af91b49d3e142b6282292b67f0 543 Gene3D G3DSA:3.40.50.300 285 522 6.4E-50 T 29-03-2018 SMALA_RS11480 983ad6af91b49d3e142b6282292b67f0 543 Pfam PF00005 ABC transporter 20 170 8.2E-26 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS11480 983ad6af91b49d3e142b6282292b67f0 543 Pfam PF00005 ABC transporter 304 450 2.2E-22 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS11480 983ad6af91b49d3e142b6282292b67f0 543 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS11480 983ad6af91b49d3e142b6282292b67f0 543 SMART SM00382 313 498 2.6E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS11480 983ad6af91b49d3e142b6282292b67f0 543 SMART SM00382 28 219 9.4E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS11480 983ad6af91b49d3e142b6282292b67f0 543 SUPERFAMILY SSF52540 2 231 3.33E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS26080 fcfda463b1157f4aeedb34fe130d5a6a 484 TIGRFAM TIGR03624 TIGR03624: putative hydrolase 83 437 4.6E-126 T 29-03-2018 IPR018766 Zinicin-like metallopeptidase type 2 SMALA_RS26080 fcfda463b1157f4aeedb34fe130d5a6a 484 Pfam PF10103 Zincin-like metallopeptidase 83 435 1.6E-129 T 29-03-2018 IPR018766 Zinicin-like metallopeptidase type 2 SMALA_RS26080 fcfda463b1157f4aeedb34fe130d5a6a 484 SUPERFAMILY SSF55486 82 437 6.96E-119 T 29-03-2018 SMALA_RS24235 7ebc3b0753ac428bc7adedf17c48d1b5 341 Gene3D G3DSA:3.40.50.300 14 338 5.5E-81 T 29-03-2018 SMALA_RS24235 7ebc3b0753ac428bc7adedf17c48d1b5 341 Pfam PF00005 ABC transporter 37 188 6.6E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS24235 7ebc3b0753ac428bc7adedf17c48d1b5 341 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS24235 7ebc3b0753ac428bc7adedf17c48d1b5 341 SMART SM00382 45 237 1.2E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS24235 7ebc3b0753ac428bc7adedf17c48d1b5 341 SUPERFAMILY SSF52540 16 259 1.05E-74 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS24235 7ebc3b0753ac428bc7adedf17c48d1b5 341 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 239 306 2.4E-17 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMALA_RS24235 7ebc3b0753ac428bc7adedf17c48d1b5 341 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 237 328 1.0E-25 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMALA_RS19840 8a53e1e4136b48a5623bec8468f1d429 246 Gene3D G3DSA:2.40.260.10 56 244 5.0E-38 T 29-03-2018 IPR023365 Sortase domain SMALA_RS19840 8a53e1e4136b48a5623bec8468f1d429 246 Pfam PF04203 Sortase family 94 229 6.7E-25 T 29-03-2018 IPR005754 Sortase family SMALA_RS19840 8a53e1e4136b48a5623bec8468f1d429 246 SUPERFAMILY SSF63817 84 233 3.4E-30 T 29-03-2018 IPR023365 Sortase domain SMALA_RS19840 8a53e1e4136b48a5623bec8468f1d429 246 TIGRFAM TIGR01076 sortase_fam: sortase 92 228 3.9E-13 T 29-03-2018 IPR005754 Sortase family SMALA_RS34475 708309ee068618aa2c73521d187cb1b7 280 Gene3D G3DSA:3.40.50.1820 3 280 8.6E-60 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS34475 708309ee068618aa2c73521d187cb1b7 280 PRINTS PR00412 Epoxide hydrolase signature 31 49 4.6E-6 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS34475 708309ee068618aa2c73521d187cb1b7 280 PRINTS PR00412 Epoxide hydrolase signature 255 277 4.6E-6 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS34475 708309ee068618aa2c73521d187cb1b7 280 PRINTS PR00412 Epoxide hydrolase signature 51 66 4.6E-6 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS34475 708309ee068618aa2c73521d187cb1b7 280 SUPERFAMILY SSF53474 3 279 7.38E-61 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS34475 708309ee068618aa2c73521d187cb1b7 280 Pfam PF00561 alpha/beta hydrolase fold 26 266 6.8E-31 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS34475 708309ee068618aa2c73521d187cb1b7 280 PRINTS PR00111 Alpha/beta hydrolase fold signature 51 66 2.1E-9 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS34475 708309ee068618aa2c73521d187cb1b7 280 PRINTS PR00111 Alpha/beta hydrolase fold signature 223 237 2.1E-9 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS34475 708309ee068618aa2c73521d187cb1b7 280 PRINTS PR00111 Alpha/beta hydrolase fold signature 95 108 2.1E-9 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS05060 6f25ad24a5a091d1aa7250a6dcc1b675 327 Gene3D G3DSA:3.40.50.720 77 268 1.4E-25 T 29-03-2018 SMALA_RS05060 6f25ad24a5a091d1aa7250a6dcc1b675 327 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 86 174 1.3E-15 T 29-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal SMALA_RS05060 6f25ad24a5a091d1aa7250a6dcc1b675 327 SUPERFAMILY SSF51735 86 277 3.15E-35 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS14090 1208f546395cc81829e06555b5533259 304 SUPERFAMILY SSF53850 89 301 3.26E-31 T 29-03-2018 SMALA_RS14090 1208f546395cc81829e06555b5533259 304 Pfam PF03466 LysR substrate binding domain 88 295 1.6E-36 T 29-03-2018 IPR005119 LysR, substrate-binding SMALA_RS14090 1208f546395cc81829e06555b5533259 304 Gene3D G3DSA:1.10.10.10 1 84 1.8E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS14090 1208f546395cc81829e06555b5533259 304 SUPERFAMILY SSF46785 2 111 2.52E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS14090 1208f546395cc81829e06555b5533259 304 Gene3D G3DSA:3.40.190.10 182 274 8.7E-20 T 29-03-2018 SMALA_RS14090 1208f546395cc81829e06555b5533259 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 3.6E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS14090 1208f546395cc81829e06555b5533259 304 Gene3D G3DSA:3.40.190.10 88 181 2.4E-15 T 29-03-2018 SMALA_RS31215 ccd13810d8860f8c1acedecd16c5b933 454 ProSitePatterns PS00691 DNA photolyases class 1 signature 2. 331 350 - T 29-03-2018 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal SMALA_RS31215 ccd13810d8860f8c1acedecd16c5b933 454 SUPERFAMILY SSF48173 190 451 3.79E-94 T 29-03-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 SMALA_RS31215 ccd13810d8860f8c1acedecd16c5b933 454 SUPERFAMILY SSF52425 4 181 1.7E-33 T 29-03-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-1368108|Reactome: R-HSA-400253 SMALA_RS31215 ccd13810d8860f8c1acedecd16c5b933 454 Pfam PF03441 FAD binding domain of DNA photolyase 264 448 1.3E-70 T 29-03-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 SMALA_RS31215 ccd13810d8860f8c1acedecd16c5b933 454 Gene3D G3DSA:1.25.40.80 130 280 4.8E-37 T 29-03-2018 SMALA_RS31215 ccd13810d8860f8c1acedecd16c5b933 454 Pfam PF00875 DNA photolyase 8 167 8.3E-34 T 29-03-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-1368108|Reactome: R-HSA-400253 SMALA_RS31215 ccd13810d8860f8c1acedecd16c5b933 454 PRINTS PR00147 DNA photolyase signature 141 157 4.0E-23 T 29-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 SMALA_RS31215 ccd13810d8860f8c1acedecd16c5b933 454 PRINTS PR00147 DNA photolyase signature 331 349 4.0E-23 T 29-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 SMALA_RS31215 ccd13810d8860f8c1acedecd16c5b933 454 PRINTS PR00147 DNA photolyase signature 370 384 4.0E-23 T 29-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 SMALA_RS31215 ccd13810d8860f8c1acedecd16c5b933 454 PRINTS PR00147 DNA photolyase signature 311 327 4.0E-23 T 29-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 SMALA_RS31215 ccd13810d8860f8c1acedecd16c5b933 454 Gene3D G3DSA:3.40.50.620 1 128 6.0E-26 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS31215 ccd13810d8860f8c1acedecd16c5b933 454 Gene3D G3DSA:1.10.579.10 282 453 3.0E-65 T 29-03-2018 SMALA_RS39485 9accd9fab059db11ca2c2e92d7adebba 410 Pfam PF14759 Reductase C-terminal 320 403 1.3E-29 T 29-03-2018 IPR028202 Reductase, C-terminal SMALA_RS39485 9accd9fab059db11ca2c2e92d7adebba 410 Gene3D G3DSA:3.50.50.60 1 98 7.7E-14 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS39485 9accd9fab059db11ca2c2e92d7adebba 410 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 301 4.4E-61 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS39485 9accd9fab059db11ca2c2e92d7adebba 410 Gene3D G3DSA:3.30.390.30 319 409 4.1E-28 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SMALA_RS39485 9accd9fab059db11ca2c2e92d7adebba 410 SUPERFAMILY SSF51905 5 311 3.63E-45 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS39485 9accd9fab059db11ca2c2e92d7adebba 410 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 7.4E-28 T 29-03-2018 SMALA_RS39485 9accd9fab059db11ca2c2e92d7adebba 410 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 144 162 7.4E-28 T 29-03-2018 SMALA_RS39485 9accd9fab059db11ca2c2e92d7adebba 410 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 255 277 7.4E-28 T 29-03-2018 SMALA_RS39485 9accd9fab059db11ca2c2e92d7adebba 410 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 230 246 7.4E-28 T 29-03-2018 SMALA_RS39485 9accd9fab059db11ca2c2e92d7adebba 410 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 99 117 7.4E-28 T 29-03-2018 SMALA_RS39485 9accd9fab059db11ca2c2e92d7adebba 410 Gene3D G3DSA:3.50.50.60 99 239 1.2E-32 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS39485 9accd9fab059db11ca2c2e92d7adebba 410 Gene3D G3DSA:3.50.50.60 242 318 1.1E-8 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS39485 9accd9fab059db11ca2c2e92d7adebba 410 SUPERFAMILY SSF55424 317 404 1.79E-26 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SMALA_RS39485 9accd9fab059db11ca2c2e92d7adebba 410 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 383 398 8.7E-20 T 29-03-2018 SMALA_RS39485 9accd9fab059db11ca2c2e92d7adebba 410 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 144 169 8.7E-20 T 29-03-2018 SMALA_RS39485 9accd9fab059db11ca2c2e92d7adebba 410 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 8.7E-20 T 29-03-2018 SMALA_RS39485 9accd9fab059db11ca2c2e92d7adebba 410 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 231 245 8.7E-20 T 29-03-2018 SMALA_RS39485 9accd9fab059db11ca2c2e92d7adebba 410 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 270 277 8.7E-20 T 29-03-2018 SMALA_RS19125 32edc765cb3631f0bdef65e6551347bb 288 Pfam PF04909 Amidohydrolase 22 288 1.8E-37 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 SMALA_RS19125 32edc765cb3631f0bdef65e6551347bb 288 Gene3D G3DSA:3.20.20.140 12 288 3.2E-46 T 29-03-2018 SMALA_RS19125 32edc765cb3631f0bdef65e6551347bb 288 SUPERFAMILY SSF51556 21 288 3.82E-56 T 29-03-2018 IPR032466 Metal-dependent hydrolase SMALA_RS22405 fa20685a9cd099457e5f11d0b3e591c3 339 SUPERFAMILY SSF51556 7 336 4.66E-71 T 29-03-2018 IPR032466 Metal-dependent hydrolase SMALA_RS22405 fa20685a9cd099457e5f11d0b3e591c3 339 ProSitePatterns PS00485 Adenosine and AMP deaminase signature. 277 283 - T 29-03-2018 IPR006650 Adenosine/AMP deaminase active site GO:0009168|GO:0019239 Reactome: R-HSA-74217 SMALA_RS22405 fa20685a9cd099457e5f11d0b3e591c3 339 Pfam PF00962 Adenosine/AMP deaminase 10 330 5.3E-92 T 29-03-2018 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 SMALA_RS22405 fa20685a9cd099457e5f11d0b3e591c3 339 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 10 333 1.0E-113 T 29-03-2018 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 SMALA_RS22405 fa20685a9cd099457e5f11d0b3e591c3 339 Gene3D G3DSA:3.20.20.140 1 339 4.9E-78 T 29-03-2018 SMALA_RS28310 8308f3362342e68a2b3c64e8b34c90d3 483 Pfam PF00171 Aldehyde dehydrogenase family 19 478 7.6E-159 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS28310 8308f3362342e68a2b3c64e8b34c90d3 483 Gene3D G3DSA:3.40.309.10 274 464 4.8E-67 T 29-03-2018 SMALA_RS28310 8308f3362342e68a2b3c64e8b34c90d3 483 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 255 262 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 SMALA_RS28310 8308f3362342e68a2b3c64e8b34c90d3 483 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 283 294 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 SMALA_RS28310 8308f3362342e68a2b3c64e8b34c90d3 483 SUPERFAMILY SSF53720 5 481 1.7E-156 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMALA_RS28310 8308f3362342e68a2b3c64e8b34c90d3 483 Gene3D G3DSA:3.40.605.10 2 273 5.3E-94 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS08575 5fb3cf251a54ab9b2e08c413f372b09e 344 Gene3D G3DSA:1.20.144.10 65 231 1.5E-17 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMALA_RS08575 5fb3cf251a54ab9b2e08c413f372b09e 344 SMART SM00014 104 219 8.3E-9 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMALA_RS08575 5fb3cf251a54ab9b2e08c413f372b09e 344 SUPERFAMILY SSF48317 26 223 4.45E-26 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMALA_RS08575 5fb3cf251a54ab9b2e08c413f372b09e 344 Pfam PF01569 PAP2 superfamily 106 221 2.8E-21 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMALA_RS27105 3f14c43300876b1f6825f8d5f44ace74 329 Pfam PF12840 Helix-turn-helix domain 264 311 3.5E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS27105 3f14c43300876b1f6825f8d5f44ace74 329 SMART SM00418 256 326 0.0042 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS27105 3f14c43300876b1f6825f8d5f44ace74 329 SUPERFAMILY SSF46785 263 326 5.27E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS27105 3f14c43300876b1f6825f8d5f44ace74 329 Gene3D G3DSA:1.10.10.10 247 327 1.5E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS18195 a958f821ffa74a3c0be93431df1a27a3 485 Gene3D G3DSA:3.40.309.10 269 459 1.1E-64 T 29-03-2018 SMALA_RS18195 a958f821ffa74a3c0be93431df1a27a3 485 SUPERFAMILY SSF53720 10 478 5.89E-151 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMALA_RS18195 a958f821ffa74a3c0be93431df1a27a3 485 Gene3D G3DSA:3.40.605.10 5 268 1.1E-80 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS18195 a958f821ffa74a3c0be93431df1a27a3 485 Pfam PF00171 Aldehyde dehydrogenase family 25 474 4.6E-154 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS18195 a958f821ffa74a3c0be93431df1a27a3 485 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 252 259 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 SMALA_RS18195 a958f821ffa74a3c0be93431df1a27a3 485 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 280 291 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 SMALA_RS38135 ca38302b19896fb56ee484789f20780a 367 Gene3D G3DSA:3.30.360.10 145 357 1.8E-30 T 29-03-2018 SMALA_RS38135 ca38302b19896fb56ee484789f20780a 367 SUPERFAMILY SSF55347 131 290 1.13E-26 T 29-03-2018 SMALA_RS38135 ca38302b19896fb56ee484789f20780a 367 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 7 120 4.7E-20 T 29-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 SMALA_RS38135 ca38302b19896fb56ee484789f20780a 367 SUPERFAMILY SSF51735 4 152 3.12E-38 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS38135 ca38302b19896fb56ee484789f20780a 367 Gene3D G3DSA:3.40.50.720 1 144 1.5E-31 T 29-03-2018 SMALA_RS32635 8d35c7b3eb28d0d9420fbf56d1b5a6e6 409 SUPERFAMILY SSF47413 5 73 1.89E-10 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS32635 8d35c7b3eb28d0d9420fbf56d1b5a6e6 409 Gene3D G3DSA:1.10.10.10 307 403 0.0012 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS32635 8d35c7b3eb28d0d9420fbf56d1b5a6e6 409 Pfam PF13560 Helix-turn-helix domain 7 65 9.3E-8 T 29-03-2018 SMALA_RS32635 8d35c7b3eb28d0d9420fbf56d1b5a6e6 409 Gene3D G3DSA:1.10.260.40 1 77 5.1E-14 T 29-03-2018 SMALA_RS32635 8d35c7b3eb28d0d9420fbf56d1b5a6e6 409 SMART SM00530 11 67 1.5E-6 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS24195 390ae9b1abfb29d7daa7514c431f4688 290 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 9 95 2.6E-6 T 29-03-2018 IPR013116 Acetohydroxy acid isomeroreductase, NADPH-binding domain KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 SMALA_RS24195 390ae9b1abfb29d7daa7514c431f4688 290 Pfam PF16896 Phosphogluconate dehydrogenase (decarboxylating) C-term 128 281 1.6E-61 T 29-03-2018 IPR031663 Phosphogluconate dehydrogenase (decarboxylating) , C-terminal SMALA_RS24195 390ae9b1abfb29d7daa7514c431f4688 290 Gene3D G3DSA:1.10.3640.10 181 280 4.4E-40 T 29-03-2018 IPR031663 Phosphogluconate dehydrogenase (decarboxylating) , C-terminal SMALA_RS24195 390ae9b1abfb29d7daa7514c431f4688 290 Gene3D G3DSA:3.40.50.720 2 180 6.9E-28 T 29-03-2018 SMALA_RS24195 390ae9b1abfb29d7daa7514c431f4688 290 SUPERFAMILY SSF51735 9 98 2.15E-16 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS04130 40cf8c59fa80406ee13550a6f552d8a4 190 Gene3D G3DSA:1.10.357.10 1 189 5.3E-31 T 29-03-2018 SMALA_RS04130 40cf8c59fa80406ee13550a6f552d8a4 190 SUPERFAMILY SSF48498 85 185 2.48E-8 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS04130 40cf8c59fa80406ee13550a6f552d8a4 190 SUPERFAMILY SSF46689 10 81 4.58E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS04130 40cf8c59fa80406ee13550a6f552d8a4 190 Pfam PF00440 Bacterial regulatory proteins, tetR family 33 63 5.2E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS42015 39247638cb25af4ba5bd68abdb0ac68b 1509 SMART SM00823 Phosphopantetheine attachment site 993 1062 3.0E-5 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS42015 39247638cb25af4ba5bd68abdb0ac68b 1509 Pfam PF00550 Phosphopantetheine attachment site 995 1058 2.7E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS42015 39247638cb25af4ba5bd68abdb0ac68b 1509 Gene3D G3DSA:3.30.300.30 878 998 4.6E-36 T 29-03-2018 SMALA_RS42015 39247638cb25af4ba5bd68abdb0ac68b 1509 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 506 907 1.0E-124 T 29-03-2018 IPR010071 Amino acid adenylation domain SMALA_RS42015 39247638cb25af4ba5bd68abdb0ac68b 1509 PIRSF PIRSF001617 1261 1383 44.0 T 29-03-2018 SMALA_RS42015 39247638cb25af4ba5bd68abdb0ac68b 1509 PIRSF PIRSF001617 925 1086 2.2E-15 T 29-03-2018 SMALA_RS42015 39247638cb25af4ba5bd68abdb0ac68b 1509 PIRSF PIRSF001617 207 597 2.5E-16 T 29-03-2018 SMALA_RS42015 39247638cb25af4ba5bd68abdb0ac68b 1509 PIRSF PIRSF001617 603 849 3.5E-6 T 29-03-2018 SMALA_RS42015 39247638cb25af4ba5bd68abdb0ac68b 1509 PIRSF PIRSF001617 848 934 2.1E-22 T 29-03-2018 SMALA_RS42015 39247638cb25af4ba5bd68abdb0ac68b 1509 Pfam PF00668 Condensation domain 26 462 4.6E-94 T 29-03-2018 IPR001242 Condensation domain SMALA_RS42015 39247638cb25af4ba5bd68abdb0ac68b 1509 Pfam PF00668 Condensation domain 1078 1500 1.5E-60 T 29-03-2018 IPR001242 Condensation domain SMALA_RS42015 39247638cb25af4ba5bd68abdb0ac68b 1509 SUPERFAMILY SSF52777 205 449 1.11E-56 T 29-03-2018 SMALA_RS42015 39247638cb25af4ba5bd68abdb0ac68b 1509 Gene3D G3DSA:3.30.559.10 1059 1279 4.1E-39 T 29-03-2018 SMALA_RS42015 39247638cb25af4ba5bd68abdb0ac68b 1509 Gene3D G3DSA:3.30.559.10 15 221 1.5E-46 T 29-03-2018 SMALA_RS42015 39247638cb25af4ba5bd68abdb0ac68b 1509 SUPERFAMILY SSF52777 1260 1495 2.0E-39 T 29-03-2018 SMALA_RS42015 39247638cb25af4ba5bd68abdb0ac68b 1509 Pfam PF00501 AMP-binding enzyme 488 883 2.6E-89 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS42015 39247638cb25af4ba5bd68abdb0ac68b 1509 Gene3D G3DSA:3.40.50.980 629 789 5.6E-28 T 29-03-2018 SMALA_RS42015 39247638cb25af4ba5bd68abdb0ac68b 1509 Pfam PF13193 AMP-binding enzyme C-terminal domain 891 966 1.5E-13 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS42015 39247638cb25af4ba5bd68abdb0ac68b 1509 Gene3D G3DSA:3.40.50.980 477 628 3.6E-46 T 29-03-2018 SMALA_RS42015 39247638cb25af4ba5bd68abdb0ac68b 1509 SUPERFAMILY SSF56801 445 1005 1.44E-146 T 29-03-2018 SMALA_RS42015 39247638cb25af4ba5bd68abdb0ac68b 1509 SUPERFAMILY SSF47336 986 1059 3.4E-19 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS42015 39247638cb25af4ba5bd68abdb0ac68b 1509 Gene3D G3DSA:1.10.1200.10 999 1058 2.8E-22 T 29-03-2018 SMALA_RS42015 39247638cb25af4ba5bd68abdb0ac68b 1509 Gene3D G3DSA:2.30.38.10 793 873 5.3E-20 T 29-03-2018 SMALA_RS42015 39247638cb25af4ba5bd68abdb0ac68b 1509 SUPERFAMILY SSF52777 1075 1272 1.67E-40 T 29-03-2018 SMALA_RS42015 39247638cb25af4ba5bd68abdb0ac68b 1509 SUPERFAMILY SSF52777 29 199 3.56E-50 T 29-03-2018 SMALA_RS22890 367a3c8a2e2c2457ccf98eba7942aa1e 283 SUPERFAMILY SSF47413 10 71 4.29E-10 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS22890 367a3c8a2e2c2457ccf98eba7942aa1e 283 SMART SM00530 17 72 1.8E-7 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS22890 367a3c8a2e2c2457ccf98eba7942aa1e 283 Pfam PF13560 Helix-turn-helix domain 13 70 3.1E-12 T 29-03-2018 SMALA_RS22890 367a3c8a2e2c2457ccf98eba7942aa1e 283 Gene3D G3DSA:1.10.260.40 3 86 2.4E-13 T 29-03-2018 SMALA_RS18415 cbab76a08058f63823cdfa0671c53d6f 318 SUPERFAMILY SSF46785 12 92 1.74E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS18415 cbab76a08058f63823cdfa0671c53d6f 318 Gene3D G3DSA:3.40.190.10 102 194 1.9E-6 T 29-03-2018 SMALA_RS18415 cbab76a08058f63823cdfa0671c53d6f 318 Pfam PF03466 LysR substrate binding domain 105 313 5.2E-16 T 29-03-2018 IPR005119 LysR, substrate-binding SMALA_RS18415 cbab76a08058f63823cdfa0671c53d6f 318 Gene3D G3DSA:3.40.190.10 195 285 2.2E-16 T 29-03-2018 SMALA_RS18415 cbab76a08058f63823cdfa0671c53d6f 318 SUPERFAMILY SSF53850 98 310 9.77E-32 T 29-03-2018 SMALA_RS18415 cbab76a08058f63823cdfa0671c53d6f 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 52 2.7E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS18415 cbab76a08058f63823cdfa0671c53d6f 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 52 63 2.7E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS18415 cbab76a08058f63823cdfa0671c53d6f 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 42 2.7E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS18415 cbab76a08058f63823cdfa0671c53d6f 318 Gene3D G3DSA:1.10.10.10 4 99 3.2E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS18415 cbab76a08058f63823cdfa0671c53d6f 318 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 16 73 3.6E-16 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS19080 7eb9e75d2ebc9c7c506536d0237bfbe6 871 SUPERFAMILY SSF49464 620 701 2.28E-10 T 29-03-2018 IPR008969 Carboxypeptidase-like, regulatory domain SMALA_RS19080 7eb9e75d2ebc9c7c506536d0237bfbe6 871 Gene3D G3DSA:2.60.40.1120 620 702 3.7E-9 T 29-03-2018 SMALA_RS19080 7eb9e75d2ebc9c7c506536d0237bfbe6 871 Gene3D G3DSA:2.60.40.10 786 857 3.2E-14 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS19080 7eb9e75d2ebc9c7c506536d0237bfbe6 871 Pfam PF07690 Major Facilitator Superfamily 53 448 1.4E-48 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS19080 7eb9e75d2ebc9c7c506536d0237bfbe6 871 PRINTS PR01036 Tetracycline resistance protein TetB signature 439 458 1.8E-9 T 29-03-2018 SMALA_RS19080 7eb9e75d2ebc9c7c506536d0237bfbe6 871 PRINTS PR01036 Tetracycline resistance protein TetB signature 52 76 1.8E-9 T 29-03-2018 SMALA_RS19080 7eb9e75d2ebc9c7c506536d0237bfbe6 871 PRINTS PR01036 Tetracycline resistance protein TetB signature 143 163 1.8E-9 T 29-03-2018 SMALA_RS19080 7eb9e75d2ebc9c7c506536d0237bfbe6 871 PRINTS PR01036 Tetracycline resistance protein TetB signature 173 197 1.8E-9 T 29-03-2018 SMALA_RS19080 7eb9e75d2ebc9c7c506536d0237bfbe6 871 SUPERFAMILY SSF103473 286 458 4.71E-66 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS19080 7eb9e75d2ebc9c7c506536d0237bfbe6 871 SUPERFAMILY SSF103473 36 233 4.71E-66 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS19080 7eb9e75d2ebc9c7c506536d0237bfbe6 871 SUPERFAMILY SSF103473 508 532 4.71E-66 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS19080 7eb9e75d2ebc9c7c506536d0237bfbe6 871 SUPERFAMILY SSF49464 704 795 7.85E-12 T 29-03-2018 IPR008969 Carboxypeptidase-like, regulatory domain SMALA_RS19080 7eb9e75d2ebc9c7c506536d0237bfbe6 871 Gene3D G3DSA:2.60.40.1120 703 785 1.1E-12 T 29-03-2018 SMALA_RS19080 7eb9e75d2ebc9c7c506536d0237bfbe6 871 SUPERFAMILY SSF49478 789 850 6.67E-13 T 29-03-2018 SMALA_RS19080 7eb9e75d2ebc9c7c506536d0237bfbe6 871 Pfam PF13620 Carboxypeptidase regulatory-like domain 704 784 2.4E-12 T 29-03-2018 SMALA_RS19080 7eb9e75d2ebc9c7c506536d0237bfbe6 871 Pfam PF13620 Carboxypeptidase regulatory-like domain 789 865 3.9E-12 T 29-03-2018 SMALA_RS19080 7eb9e75d2ebc9c7c506536d0237bfbe6 871 Pfam PF13620 Carboxypeptidase regulatory-like domain 621 698 1.2E-9 T 29-03-2018 SMALA_RS19080 7eb9e75d2ebc9c7c506536d0237bfbe6 871 Gene3D G3DSA:1.20.1250.20 48 237 2.3E-31 T 29-03-2018 SMALA_RS19080 7eb9e75d2ebc9c7c506536d0237bfbe6 871 Gene3D G3DSA:1.20.1250.20 290 548 2.7E-32 T 29-03-2018 SMALA_RS28425 5b2723685ea78ac8dcae464b92d550c5 386 PIRSF PIRSF004640 11 373 7.9E-146 T 29-03-2018 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 SMALA_RS28425 5b2723685ea78ac8dcae464b92d550c5 386 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 16 367 33.674 T 29-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 SMALA_RS28425 5b2723685ea78ac8dcae464b92d550c5 386 SUPERFAMILY SSF51717 46 219 1.88E-9 T 29-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMALA_RS28425 5b2723685ea78ac8dcae464b92d550c5 386 Pfam PF04551 GcpE protein 22 361 2.2E-133 T 29-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 SMALA_RS28425 5b2723685ea78ac8dcae464b92d550c5 386 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 18 360 5.8E-128 T 29-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 SMALA_RS28425 5b2723685ea78ac8dcae464b92d550c5 386 Gene3D G3DSA:3.20.20.120 26 159 1.9E-16 T 29-03-2018 IPR029065 Enolase C-terminal domain-like SMALA_RS28425 5b2723685ea78ac8dcae464b92d550c5 386 SUPERFAMILY SSF56014 275 359 3.62E-11 T 29-03-2018 SMALA_RS39475 40d8a2d3aec39753ca7a132610051b83 236 Pfam PF03737 Aldolase/RraA 26 172 2.8E-41 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein SMALA_RS39475 40d8a2d3aec39753ca7a132610051b83 236 Gene3D G3DSA:3.50.30.40 17 192 5.1E-55 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein SMALA_RS39475 40d8a2d3aec39753ca7a132610051b83 236 SUPERFAMILY SSF89562 22 183 1.15E-51 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein SMALA_RS39475 40d8a2d3aec39753ca7a132610051b83 236 TIGRFAM TIGR02798 ligK_PcmE: 4-carboxy-4-hydroxy-2-oxoadipate aldolase/oxaloacetate decarboxylase 3 223 9.8E-99 T 29-03-2018 IPR014165 4-carboxy-4-hydroxy-2-oxoadipate aldolase/oxaloacetate decarboxylase KEGG: 00362+4.1.3.17|KEGG: 00660+4.1.3.17|MetaCyc: PWY-7701 SMALA_RS23815 2a737e970a254bcb06411f9b9933499b 509 Pfam PF00743 Flavin-binding monooxygenase-like 10 215 2.8E-18 T 29-03-2018 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 SMALA_RS23815 2a737e970a254bcb06411f9b9933499b 509 SUPERFAMILY SSF51905 257 463 1.1E-21 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS23815 2a737e970a254bcb06411f9b9933499b 509 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 132 140 5.2E-7 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMALA_RS23815 2a737e970a254bcb06411f9b9933499b 509 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 10 32 5.2E-7 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMALA_RS23815 2a737e970a254bcb06411f9b9933499b 509 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 171 195 5.2E-7 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMALA_RS23815 2a737e970a254bcb06411f9b9933499b 509 Gene3D G3DSA:3.50.50.60 165 490 4.0E-53 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS23815 2a737e970a254bcb06411f9b9933499b 509 Gene3D G3DSA:3.50.50.60 8 164 2.9E-40 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS23815 2a737e970a254bcb06411f9b9933499b 509 SUPERFAMILY SSF51905 8 265 2.27E-60 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS35105 d0c59e0b835fd96b8956068e062f1fde 180 SUPERFAMILY SSF88659 108 172 1.2E-12 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS35105 d0c59e0b835fd96b8956068e062f1fde 180 Gene3D G3DSA:1.10.1740.10 3 84 1.4E-10 T 29-03-2018 SMALA_RS35105 d0c59e0b835fd96b8956068e062f1fde 180 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 17 172 1.9E-14 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS35105 d0c59e0b835fd96b8956068e062f1fde 180 Gene3D G3DSA:1.10.10.10 85 179 3.0E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS35105 d0c59e0b835fd96b8956068e062f1fde 180 Pfam PF08281 Sigma-70, region 4 116 162 3.8E-9 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS35105 d0c59e0b835fd96b8956068e062f1fde 180 SUPERFAMILY SSF88946 11 88 3.92E-10 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS35105 d0c59e0b835fd96b8956068e062f1fde 180 Pfam PF04542 Sigma-70 region 2 20 57 1.2E-6 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS13865 073393a9c664f1cf8cd5aa631f4fbced 628 Gene3D G3DSA:3.40.50.1220 220 393 2.7E-39 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain SMALA_RS13865 073393a9c664f1cf8cd5aa631f4fbced 628 SUPERFAMILY SSF52518 400 616 1.09E-49 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold SMALA_RS13865 073393a9c664f1cf8cd5aa631f4fbced 628 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 223 357 6.9E-32 T 29-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 SMALA_RS13865 073393a9c664f1cf8cd5aa631f4fbced 628 SUPERFAMILY SSF52518 7 214 1.55E-29 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold SMALA_RS13865 073393a9c664f1cf8cd5aa631f4fbced 628 TIGRFAM TIGR04377 myo_inos_iolD: 3,5/4-trihydroxycyclohexa-1,2-dione hydrolase 8 625 2.4E-273 T 29-03-2018 IPR030817 3,5/4-Trihydroxycyclohexa-1,2-dione hydrolase GO:0016823|GO:0019310|GO:0030976 KEGG: 00562+3.7.1.22 SMALA_RS13865 073393a9c664f1cf8cd5aa631f4fbced 628 Gene3D G3DSA:3.40.50.970 394 624 1.8E-43 T 29-03-2018 SMALA_RS13865 073393a9c664f1cf8cd5aa631f4fbced 628 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 421 579 9.2E-41 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 SMALA_RS13865 073393a9c664f1cf8cd5aa631f4fbced 628 SUPERFAMILY SSF52467 190 371 1.9E-41 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain SMALA_RS13865 073393a9c664f1cf8cd5aa631f4fbced 628 Gene3D G3DSA:3.40.50.970 2 219 2.0E-45 T 29-03-2018 SMALA_RS13865 073393a9c664f1cf8cd5aa631f4fbced 628 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 10 203 1.5E-33 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 SMALA_RS28920 bf6120e52f3b29b8a177d08375429fc8 732 Pfam PF04607 Region found in RelA / SpoT proteins 296 369 7.2E-14 T 29-03-2018 IPR007685 RelA/SpoT GO:0015969 SMALA_RS28920 bf6120e52f3b29b8a177d08375429fc8 732 SMART SM00471 83 193 1.3E-11 T 29-03-2018 IPR003607 HD/PDEase domain SMALA_RS28920 bf6120e52f3b29b8a177d08375429fc8 732 SUPERFAMILY SSF81301 232 407 6.05E-32 T 29-03-2018 SMALA_RS28920 bf6120e52f3b29b8a177d08375429fc8 732 Gene3D G3DSA:3.30.70.260 646 724 3.6E-7 T 29-03-2018 SMALA_RS28920 bf6120e52f3b29b8a177d08375429fc8 732 SUPERFAMILY SSF81271 431 489 1.79E-9 T 29-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 SMALA_RS28920 bf6120e52f3b29b8a177d08375429fc8 732 Gene3D G3DSA:3.10.20.30 424 500 1.1E-20 T 29-03-2018 IPR012675 Beta-grasp domain SMALA_RS28920 bf6120e52f3b29b8a177d08375429fc8 732 Pfam PF02824 TGS domain 431 489 4.2E-13 T 29-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 SMALA_RS28920 bf6120e52f3b29b8a177d08375429fc8 732 SUPERFAMILY SSF55021 648 722 1.64E-6 T 29-03-2018 SMALA_RS28920 bf6120e52f3b29b8a177d08375429fc8 732 Pfam PF13328 HD domain 68 215 3.9E-39 T 29-03-2018 IPR003607 HD/PDEase domain SMALA_RS28920 bf6120e52f3b29b8a177d08375429fc8 732 SUPERFAMILY SSF109604 47 231 1.66E-61 T 29-03-2018 SMALA_RS28920 bf6120e52f3b29b8a177d08375429fc8 732 Pfam PF13291 ACT domain 646 722 1.5E-12 T 29-03-2018 IPR002912 ACT domain SMALA_RS28920 bf6120e52f3b29b8a177d08375429fc8 732 Gene3D G3DSA:3.30.460.10 228 363 9.2E-21 T 29-03-2018 SMALA_RS28920 bf6120e52f3b29b8a177d08375429fc8 732 SMART SM00954 274 382 1.1E-24 T 29-03-2018 IPR007685 RelA/SpoT GO:0015969 SMALA_RS18445 4b98e0da0f504cd7d7913ad3997a2288 270 SUPERFAMILY SSF46785 19 83 4.52E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS18445 4b98e0da0f504cd7d7913ad3997a2288 270 Gene3D G3DSA:1.10.10.10 5 102 1.0E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS18445 4b98e0da0f504cd7d7913ad3997a2288 270 Pfam PF09339 IclR helix-turn-helix domain 19 65 1.6E-12 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMALA_RS18445 4b98e0da0f504cd7d7913ad3997a2288 270 Gene3D G3DSA:3.30.450.40 103 264 3.0E-42 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS18445 4b98e0da0f504cd7d7913ad3997a2288 270 SUPERFAMILY SSF55781 70 255 1.63E-41 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS18445 4b98e0da0f504cd7d7913ad3997a2288 270 SMART SM00346 13 102 8.3E-15 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMALA_RS18445 4b98e0da0f504cd7d7913ad3997a2288 270 Pfam PF01614 Bacterial transcriptional regulator 130 251 3.1E-20 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal SMALA_RS28300 afebe83247dcf32d893be839e2d3abe4 453 Gene3D G3DSA:3.40.640.10 63 323 2.2E-74 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS28300 afebe83247dcf32d893be839e2d3abe4 453 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 251 288 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMALA_RS28300 afebe83247dcf32d893be839e2d3abe4 453 Pfam PF00202 Aminotransferase class-III 29 444 7.0E-93 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMALA_RS28300 afebe83247dcf32d893be839e2d3abe4 453 SUPERFAMILY SSF53383 9 448 2.02E-126 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS28300 afebe83247dcf32d893be839e2d3abe4 453 Gene3D G3DSA:3.90.1150.10 324 453 6.4E-20 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS28300 afebe83247dcf32d893be839e2d3abe4 453 PIRSF PIRSF000521 25 448 4.8E-22 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMALA_RS19620 f1339581ec6b4424fffa738d41fe6f96 360 PIRSF PIRSF015578 1 358 1.3E-90 T 29-03-2018 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 SMALA_RS19620 f1339581ec6b4424fffa738d41fe6f96 360 Pfam PF01658 Myo-inositol-1-phosphate synthase 191 300 7.5E-32 T 29-03-2018 IPR013021 Myo-inositol-1-phosphate synthase, GAPDH-like KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 SMALA_RS19620 f1339581ec6b4424fffa738d41fe6f96 360 SUPERFAMILY SSF55347 190 299 1.57E-34 T 29-03-2018 SMALA_RS19620 f1339581ec6b4424fffa738d41fe6f96 360 SUPERFAMILY SSF51735 3 185 1.92E-91 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS19620 f1339581ec6b4424fffa738d41fe6f96 360 SUPERFAMILY SSF51735 297 356 1.92E-91 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS19620 f1339581ec6b4424fffa738d41fe6f96 360 TIGRFAM TIGR03450 mycothiol_INO1: inositol 1-phosphate synthase 4 354 3.7E-219 T 29-03-2018 IPR017815 Myo-inositol 1-phosphate synthase, actinobacteria SMALA_RS19620 f1339581ec6b4424fffa738d41fe6f96 360 Gene3D G3DSA:3.40.50.720 294 355 1.2E-14 T 29-03-2018 SMALA_RS19620 f1339581ec6b4424fffa738d41fe6f96 360 Gene3D G3DSA:3.40.50.720 1 200 5.0E-52 T 29-03-2018 SMALA_RS19620 f1339581ec6b4424fffa738d41fe6f96 360 Gene3D G3DSA:3.30.360.10 201 293 8.9E-35 T 29-03-2018 SMALA_RS20460 0e5f924ca51458c2b112d370410e073c 1067 SUPERFAMILY SSF46894 2 81 4.82E-12 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS20460 0e5f924ca51458c2b112d370410e073c 1067 SUPERFAMILY SSF48452 674 877 2.65E-25 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS20460 0e5f924ca51458c2b112d370410e073c 1067 Gene3D G3DSA:1.10.150.200 897 934 1.8E-5 T 29-03-2018 SMALA_RS20460 0e5f924ca51458c2b112d370410e073c 1067 Gene3D G3DSA:1.10.150.200 847 896 3.3E-9 T 29-03-2018 SMALA_RS20460 0e5f924ca51458c2b112d370410e073c 1067 Gene3D G3DSA:1.10.150.200 778 817 9.7E-8 T 29-03-2018 SMALA_RS20460 0e5f924ca51458c2b112d370410e073c 1067 Gene3D G3DSA:1.10.150.200 706 777 6.5E-9 T 29-03-2018 SMALA_RS20460 0e5f924ca51458c2b112d370410e073c 1067 Pfam PF00931 NB-ARC domain 314 545 1.4E-7 T 29-03-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207 SMALA_RS20460 0e5f924ca51458c2b112d370410e073c 1067 Gene3D G3DSA:1.10.10.10 6 102 4.1E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS20460 0e5f924ca51458c2b112d370410e073c 1067 Gene3D G3DSA:3.30.70.100 818 846 6.9E-7 T 29-03-2018 SMALA_RS20460 0e5f924ca51458c2b112d370410e073c 1067 Gene3D G3DSA:1.25.40.10 103 272 1.5E-24 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS20460 0e5f924ca51458c2b112d370410e073c 1067 Pfam PF03704 Bacterial transcriptional activator domain 101 245 1.4E-33 T 29-03-2018 IPR005158 Bacterial transcriptional activator domain SMALA_RS20460 0e5f924ca51458c2b112d370410e073c 1067 Gene3D G3DSA:1.25.40.10 935 1056 3.5E-15 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS20460 0e5f924ca51458c2b112d370410e073c 1067 SUPERFAMILY SSF52540 280 542 1.23E-24 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS20460 0e5f924ca51458c2b112d370410e073c 1067 SMART SM00862 15 94 5.9E-10 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS20460 0e5f924ca51458c2b112d370410e073c 1067 PRINTS PR00364 Disease resistance protein signature 312 327 2.5E-9 T 29-03-2018 SMALA_RS20460 0e5f924ca51458c2b112d370410e073c 1067 PRINTS PR00364 Disease resistance protein signature 475 489 2.5E-9 T 29-03-2018 SMALA_RS20460 0e5f924ca51458c2b112d370410e073c 1067 PRINTS PR00364 Disease resistance protein signature 1033 1049 2.5E-9 T 29-03-2018 SMALA_RS20460 0e5f924ca51458c2b112d370410e073c 1067 PRINTS PR00364 Disease resistance protein signature 391 405 2.5E-9 T 29-03-2018 SMALA_RS20460 0e5f924ca51458c2b112d370410e073c 1067 SMART SM00028 928 961 0.63 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS20460 0e5f924ca51458c2b112d370410e073c 1067 SMART SM00028 728 761 82.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS20460 0e5f924ca51458c2b112d370410e073c 1067 SMART SM00028 888 921 69.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS20460 0e5f924ca51458c2b112d370410e073c 1067 SMART SM00028 768 801 14.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS20460 0e5f924ca51458c2b112d370410e073c 1067 SMART SM00028 968 1001 160.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS20460 0e5f924ca51458c2b112d370410e073c 1067 SMART SM00028 1008 1041 29.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS20460 0e5f924ca51458c2b112d370410e073c 1067 SMART SM00028 808 841 17.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS20460 0e5f924ca51458c2b112d370410e073c 1067 SMART SM00028 848 881 5.2 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS20460 0e5f924ca51458c2b112d370410e073c 1067 Pfam PF00486 Transcriptional regulatory protein, C terminal 22 77 9.3E-7 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS20460 0e5f924ca51458c2b112d370410e073c 1067 SUPERFAMILY SSF48452 97 259 2.44E-29 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS20460 0e5f924ca51458c2b112d370410e073c 1067 SMART SM01043 101 245 6.9E-40 T 29-03-2018 IPR005158 Bacterial transcriptional activator domain SMALA_RS20460 0e5f924ca51458c2b112d370410e073c 1067 Pfam PF13424 Tetratricopeptide repeat 808 879 3.5E-11 T 29-03-2018 SMALA_RS20460 0e5f924ca51458c2b112d370410e073c 1067 Pfam PF13424 Tetratricopeptide repeat 730 797 1.6E-9 T 29-03-2018 SMALA_RS20460 0e5f924ca51458c2b112d370410e073c 1067 Pfam PF13424 Tetratricopeptide repeat 888 959 1.2E-7 T 29-03-2018 SMALA_RS20460 0e5f924ca51458c2b112d370410e073c 1067 Gene3D G3DSA:3.40.50.300 273 431 3.9E-12 T 29-03-2018 SMALA_RS20460 0e5f924ca51458c2b112d370410e073c 1067 SUPERFAMILY SSF48452 839 1039 2.58E-29 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS24110 87862a320bd94504793615ef692f9760 856 Gene3D G3DSA:1.20.1250.20 241 853 1.5E-5 T 29-03-2018 SMALA_RS24110 87862a320bd94504793615ef692f9760 856 Pfam PF12704 MacB-like periplasmic core domain 19 233 5.0E-14 T 29-03-2018 IPR025857 MacB-like periplasmic core domain SMALA_RS24110 87862a320bd94504793615ef692f9760 856 Pfam PF12704 MacB-like periplasmic core domain 496 695 1.1E-7 T 29-03-2018 IPR025857 MacB-like periplasmic core domain SMALA_RS24110 87862a320bd94504793615ef692f9760 856 Pfam PF02687 FtsX-like permease family 296 391 6.6E-14 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 SMALA_RS24110 87862a320bd94504793615ef692f9760 856 Pfam PF02687 FtsX-like permease family 758 848 2.4E-13 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 SMALA_RS10850 4f434cf76b6b3600248a4c662524840c 888 Gene3D G3DSA:2.60.40.1130 42 146 1.1E-20 T 29-03-2018 SMALA_RS10850 4f434cf76b6b3600248a4c662524840c 888 SUPERFAMILY SSF51445 247 790 1.55E-115 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS10850 4f434cf76b6b3600248a4c662524840c 888 SUPERFAMILY SSF81296 155 252 1.4E-19 T 29-03-2018 IPR014756 Immunoglobulin E-set SMALA_RS10850 4f434cf76b6b3600248a4c662524840c 888 SUPERFAMILY SSF51011 793 883 7.91E-23 T 29-03-2018 SMALA_RS10850 4f434cf76b6b3600248a4c662524840c 888 Gene3D G3DSA:3.20.20.80 250 824 1.1E-78 T 29-03-2018 SMALA_RS10850 4f434cf76b6b3600248a4c662524840c 888 Gene3D G3DSA:2.60.40.1180 825 884 2.1E-21 T 29-03-2018 SMALA_RS10850 4f434cf76b6b3600248a4c662524840c 888 Gene3D G3DSA:2.60.40.10 148 249 3.3E-21 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS10850 4f434cf76b6b3600248a4c662524840c 888 SUPERFAMILY SSF81296 39 147 6.3E-19 T 29-03-2018 IPR014756 Immunoglobulin E-set SMALA_RS10850 4f434cf76b6b3600248a4c662524840c 888 TIGRFAM TIGR02103 pullul_strch: alpha-1,6-glucosidases, pullulanase-type 44 882 3.3E-280 T 29-03-2018 IPR011839 Alpha-1,6-glucosidases, pullulanase-type GO:0005975|GO:0051060 SMALA_RS10850 4f434cf76b6b3600248a4c662524840c 888 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 157 235 7.2E-9 T 29-03-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077 SMALA_RS10850 4f434cf76b6b3600248a4c662524840c 888 Pfam PF11852 Domain of unknown function (DUF3372) 733 882 4.6E-42 T 29-03-2018 IPR024561 Alpha-1,6-glucosidases, pullulanase-type, C-terminal SMALA_RS24130 6f057ed433a3222950ece5ac4ce8540e 56 Pfam PF00741 Gas vesicle protein 3 39 2.3E-14 T 29-03-2018 IPR000638 Gas vesicle protein GvpA GO:0005198|GO:0012506 SMALA_RS24485 bb2e83671840f33484332c7df23e4f70 200 Gene3D G3DSA:1.10.10.60 35 53 1.4E-6 T 29-03-2018 SMALA_RS24485 bb2e83671840f33484332c7df23e4f70 200 Gene3D G3DSA:1.10.357.10 54 167 1.5E-5 T 29-03-2018 SMALA_RS24485 bb2e83671840f33484332c7df23e4f70 200 SUPERFAMILY SSF46689 3 63 1.13E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS24485 bb2e83671840f33484332c7df23e4f70 200 Gene3D G3DSA:1.10.10.60 1 34 5.7E-8 T 29-03-2018 SMALA_RS09605 39682303744353f3426adce52c3949fd 755 Hamap MF_00203 UvrABC system protein C [uvrC]. 4 720 30.432 T 29-03-2018 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 SMALA_RS09605 39682303744353f3426adce52c3949fd 755 Gene3D G3DSA:4.10.860.10 186 248 1.4E-14 T 29-03-2018 IPR001943 UVR domain GO:0005515 SMALA_RS09605 39682303744353f3426adce52c3949fd 755 SUPERFAMILY SSF46600 195 246 2.35E-13 T 29-03-2018 IPR001943 UVR domain GO:0005515 SMALA_RS09605 39682303744353f3426adce52c3949fd 755 Gene3D G3DSA:3.40.1440.10 5 102 6.7E-23 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily SMALA_RS09605 39682303744353f3426adce52c3949fd 755 Pfam PF14520 Helix-hairpin-helix domain 671 721 1.9E-9 T 29-03-2018 SMALA_RS09605 39682303744353f3426adce52c3949fd 755 Gene3D G3DSA:1.10.150.20 659 722 3.1E-14 T 29-03-2018 SMALA_RS09605 39682303744353f3426adce52c3949fd 755 SUPERFAMILY SSF47781 612 722 7.31E-23 T 29-03-2018 IPR010994 RuvA domain 2-like SMALA_RS09605 39682303744353f3426adce52c3949fd 755 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 11 467 5.0E-130 T 29-03-2018 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 SMALA_RS09605 39682303744353f3426adce52c3949fd 755 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 393 655 6.8E-54 T 29-03-2018 IPR001162 UvrC family homology region SMALA_RS09605 39682303744353f3426adce52c3949fd 755 SMART SM00278 701 720 0.087 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 SMALA_RS09605 39682303744353f3426adce52c3949fd 755 SMART SM00278 669 688 120.0 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 SMALA_RS09605 39682303744353f3426adce52c3949fd 755 SUPERFAMILY SSF82771 17 101 2.09E-23 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily SMALA_RS09605 39682303744353f3426adce52c3949fd 755 SMART SM00465 17 99 1.1E-20 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily SMALA_RS09605 39682303744353f3426adce52c3949fd 755 Pfam PF01541 GIY-YIG catalytic domain 19 92 1.8E-11 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily SMALA_RS09605 39682303744353f3426adce52c3949fd 755 Pfam PF02151 UvrB/uvrC motif 210 242 2.7E-10 T 29-03-2018 IPR001943 UVR domain GO:0005515 SMALA_RS13060 023770f181d6538b0323d4e85d7e9d93 217 Gene3D G3DSA:3.40.50.1240 10 210 3.4E-51 T 29-03-2018 IPR029033 Histidine phosphatase superfamily SMALA_RS13060 023770f181d6538b0323d4e85d7e9d93 217 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 12 204 1.1E-54 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SMALA_RS13060 023770f181d6538b0323d4e85d7e9d93 217 PIRSF PIRSF000709 7 180 8.9E-11 T 29-03-2018 SMALA_RS13060 023770f181d6538b0323d4e85d7e9d93 217 SUPERFAMILY SSF53254 10 210 6.93E-55 T 29-03-2018 IPR029033 Histidine phosphatase superfamily SMALA_RS13060 023770f181d6538b0323d4e85d7e9d93 217 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 14 23 - T 29-03-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 SMALA_RS13060 023770f181d6538b0323d4e85d7e9d93 217 SMART SM00855 11 165 2.2E-23 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SMALA_RS02645 a74a0d01fba88c05653e62f7b20e277c 447 SUPERFAMILY SSF53850 21 444 4.0E-48 T 29-03-2018 SMALA_RS02645 a74a0d01fba88c05653e62f7b20e277c 447 Pfam PF01547 Bacterial extracellular solute-binding protein 53 322 1.9E-26 T 29-03-2018 IPR006059 Solute-binding family 1 GO:0006810 SMALA_RS02645 a74a0d01fba88c05653e62f7b20e277c 447 Gene3D G3DSA:3.40.190.10 154 447 1.1E-34 T 29-03-2018 SMALA_RS18315 68571629fb8e1eddf0dd1d5174c6c26b 229 SMART SM00448 3 116 3.8E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS18315 68571629fb8e1eddf0dd1d5174c6c26b 229 Gene3D G3DSA:1.10.10.10 128 211 2.6E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS18315 68571629fb8e1eddf0dd1d5174c6c26b 229 SUPERFAMILY SSF46894 130 208 9.86E-23 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS18315 68571629fb8e1eddf0dd1d5174c6c26b 229 Pfam PF00196 Bacterial regulatory proteins, luxR family 146 201 2.3E-21 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS18315 68571629fb8e1eddf0dd1d5174c6c26b 229 ProSitePatterns PS00622 LuxR-type HTH domain signature. 161 188 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS18315 68571629fb8e1eddf0dd1d5174c6c26b 229 Gene3D G3DSA:3.40.50.2300 2 127 1.3E-35 T 29-03-2018 SMALA_RS18315 68571629fb8e1eddf0dd1d5174c6c26b 229 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 177 189 1.5E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS18315 68571629fb8e1eddf0dd1d5174c6c26b 229 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 147 161 1.5E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS18315 68571629fb8e1eddf0dd1d5174c6c26b 229 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 161 177 1.5E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS18315 68571629fb8e1eddf0dd1d5174c6c26b 229 SMART SM00421 144 201 9.4E-25 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS18315 68571629fb8e1eddf0dd1d5174c6c26b 229 SUPERFAMILY SSF52172 3 133 3.84E-33 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS18315 68571629fb8e1eddf0dd1d5174c6c26b 229 Pfam PF00072 Response regulator receiver domain 5 117 9.8E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS22565 56f9d75e37e47dcd4a3d411e78c40c92 275 SMART SM00322 59 124 1.6E-7 T 29-03-2018 IPR004087 K Homology domain GO:0003676 SMALA_RS22565 56f9d75e37e47dcd4a3d411e78c40c92 275 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 207 5.9E-93 T 29-03-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 SMALA_RS22565 56f9d75e37e47dcd4a3d411e78c40c92 275 Pfam PF07650 KH domain 38 109 5.8E-19 T 29-03-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMALA_RS22565 56f9d75e37e47dcd4a3d411e78c40c92 275 SUPERFAMILY SSF54821 106 205 1.09E-37 T 29-03-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMALA_RS22565 56f9d75e37e47dcd4a3d411e78c40c92 275 ProSitePatterns PS00548 Ribosomal protein S3 signature. 162 196 - T 29-03-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMALA_RS22565 56f9d75e37e47dcd4a3d411e78c40c92 275 Gene3D G3DSA:3.30.1140.32 107 207 9.0E-36 T 29-03-2018 SMALA_RS22565 56f9d75e37e47dcd4a3d411e78c40c92 275 SUPERFAMILY SSF54814 2 105 1.13E-34 T 29-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 SMALA_RS22565 56f9d75e37e47dcd4a3d411e78c40c92 275 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 205 37.896 T 29-03-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 SMALA_RS22565 56f9d75e37e47dcd4a3d411e78c40c92 275 Pfam PF00189 Ribosomal protein S3, C-terminal domain 119 201 2.0E-36 T 29-03-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMALA_RS22565 56f9d75e37e47dcd4a3d411e78c40c92 275 Gene3D G3DSA:3.30.300.20 17 106 1.5E-29 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta SMALA_RS00835 a10b9b0d0b838f306edf6c9a04d2997e 681 Pfam PF01564 Spermine/spermidine synthase domain 268 386 9.5E-8 T 29-03-2018 SMALA_RS00835 a10b9b0d0b838f306edf6c9a04d2997e 681 SUPERFAMILY SSF53335 261 412 1.64E-25 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS00835 a10b9b0d0b838f306edf6c9a04d2997e 681 Gene3D G3DSA:3.40.50.150 239 426 6.9E-21 T 29-03-2018 SMALA_RS37165 d77993016e11041d08dad0b1abb8723e 277 Pfam PF03473 MOSC domain 141 265 9.5E-26 T 29-03-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 SMALA_RS37165 d77993016e11041d08dad0b1abb8723e 277 Gene3D G3DSA:2.40.33.20 1 274 7.8E-47 T 29-03-2018 SMALA_RS37165 d77993016e11041d08dad0b1abb8723e 277 SUPERFAMILY SSF50800 2 51 2.2E-16 T 29-03-2018 IPR011037 Pyruvate kinase-like, insert domain SMALA_RS37165 d77993016e11041d08dad0b1abb8723e 277 SUPERFAMILY SSF50800 148 268 2.2E-16 T 29-03-2018 IPR011037 Pyruvate kinase-like, insert domain SMALA_RS37165 d77993016e11041d08dad0b1abb8723e 277 Pfam PF03476 MOSC N-terminal beta barrel domain 1 118 2.9E-31 T 29-03-2018 IPR005303 MOSC, N-terminal beta barrel SMALA_RS37165 d77993016e11041d08dad0b1abb8723e 277 SUPERFAMILY SSF141673 6 132 4.05E-33 T 29-03-2018 SMALA_RS09560 da87a653b87177a9110ddf4fdb9660f8 111 Gene3D G3DSA:2.20.28.10 16 70 8.3E-4 T 29-03-2018 SMALA_RS09560 da87a653b87177a9110ddf4fdb9660f8 111 Pfam PF13397 RNA polymerase-binding protein 5 108 1.1E-42 T 29-03-2018 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 SMALA_RS09560 da87a653b87177a9110ddf4fdb9660f8 111 Hamap MF_01483 RNA polymerase-binding protein RbpA [rbpA]. 17 110 23.781 T 29-03-2018 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 SMALA_RS09560 da87a653b87177a9110ddf4fdb9660f8 111 ProSitePatterns PS00202 Rubredoxin signature. 51 61 - T 29-03-2018 IPR018527 Rubredoxin, iron-binding site GO:0046872 SMALA_RS19220 b74130931bec3e7ea90201229cc2f992 108 Gene3D G3DSA:3.30.1190.10 46 92 4.1E-9 T 29-03-2018 SMALA_RS19220 b74130931bec3e7ea90201229cc2f992 108 SUPERFAMILY SSF47413 27 86 8.89E-12 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS19220 b74130931bec3e7ea90201229cc2f992 108 SMART SM00530 27 82 1.4E-6 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS19220 b74130931bec3e7ea90201229cc2f992 108 Gene3D G3DSA:1.10.10.10 3 45 1.7E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS19220 b74130931bec3e7ea90201229cc2f992 108 Pfam PF01381 Helix-turn-helix 34 78 8.1E-9 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS41850 df652eee097dc0ec3e22ea499a8a880d 454 SMART SM00450 357 450 2.2E-13 T 29-03-2018 IPR001763 Rhodanese-like domain SMALA_RS41850 df652eee097dc0ec3e22ea499a8a880d 454 SUPERFAMILY SSF56281 8 240 5.46E-38 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS41850 df652eee097dc0ec3e22ea499a8a880d 454 SMART SM00849 13 180 4.2E-17 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS41850 df652eee097dc0ec3e22ea499a8a880d 454 Gene3D G3DSA:3.40.250.10 247 342 6.0E-7 T 29-03-2018 IPR001763 Rhodanese-like domain SMALA_RS41850 df652eee097dc0ec3e22ea499a8a880d 454 SUPERFAMILY SSF52821 219 352 9.79E-14 T 29-03-2018 IPR001763 Rhodanese-like domain SMALA_RS41850 df652eee097dc0ec3e22ea499a8a880d 454 Gene3D G3DSA:3.60.15.10 1 240 3.4E-28 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS41850 df652eee097dc0ec3e22ea499a8a880d 454 Gene3D G3DSA:3.40.250.10 343 454 2.5E-20 T 29-03-2018 IPR001763 Rhodanese-like domain SMALA_RS41850 df652eee097dc0ec3e22ea499a8a880d 454 SUPERFAMILY SSF52821 341 453 5.76E-24 T 29-03-2018 IPR001763 Rhodanese-like domain SMALA_RS41850 df652eee097dc0ec3e22ea499a8a880d 454 Pfam PF00581 Rhodanese-like domain 360 443 5.3E-7 T 29-03-2018 IPR001763 Rhodanese-like domain SMALA_RS37450 cc79c0572c2470b94f709cd145a35067 803 TIGRFAM TIGR00143 hypF: carbamoyltransferase HypF 60 797 8.9E-218 T 29-03-2018 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 SMALA_RS37450 cc79c0572c2470b94f709cd145a35067 803 Gene3D G3DSA:2.10.290.10 155 244 3.9E-5 T 29-03-2018 SMALA_RS37450 cc79c0572c2470b94f709cd145a35067 803 PIRSF PIRSF006256 52 803 9.1E-267 T 29-03-2018 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 SMALA_RS37450 cc79c0572c2470b94f709cd145a35067 803 SUPERFAMILY SSF54975 54 141 6.11E-20 T 29-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 SMALA_RS37450 cc79c0572c2470b94f709cd145a35067 803 Gene3D G3DSA:3.30.70.100 47 148 9.8E-22 T 29-03-2018 SMALA_RS37450 cc79c0572c2470b94f709cd145a35067 803 SUPERFAMILY SSF53067 534 585 8.85E-5 T 29-03-2018 SMALA_RS37450 cc79c0572c2470b94f709cd145a35067 803 SUPERFAMILY SSF53067 689 798 8.85E-5 T 29-03-2018 SMALA_RS37450 cc79c0572c2470b94f709cd145a35067 803 ProSitePatterns PS00150 Acylphosphatase signature 1. 61 71 - T 29-03-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 SMALA_RS37450 cc79c0572c2470b94f709cd145a35067 803 SUPERFAMILY SSF55821 225 443 3.05E-42 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain SMALA_RS37450 cc79c0572c2470b94f709cd145a35067 803 Gene3D G3DSA:3.90.870.10 245 417 1.8E-42 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain SMALA_RS37450 cc79c0572c2470b94f709cd145a35067 803 Pfam PF07503 HypF finger 158 190 2.4E-14 T 29-03-2018 IPR011125 Zinc finger, HypF-type GO:0008270 SMALA_RS37450 cc79c0572c2470b94f709cd145a35067 803 Pfam PF07503 HypF finger 208 240 3.8E-17 T 29-03-2018 IPR011125 Zinc finger, HypF-type GO:0008270 SMALA_RS37450 cc79c0572c2470b94f709cd145a35067 803 Pfam PF01300 Telomere recombination 258 437 7.0E-45 T 29-03-2018 IPR006070 YrdC-like domain GO:0003725 SMALA_RS37450 cc79c0572c2470b94f709cd145a35067 803 Gene3D G3DSA:3.30.420.40 418 554 4.6E-4 T 29-03-2018 SMALA_RS37450 cc79c0572c2470b94f709cd145a35067 803 Gene3D G3DSA:3.30.420.40 634 775 4.7E-31 T 29-03-2018 SMALA_RS37450 cc79c0572c2470b94f709cd145a35067 803 Pfam PF00708 Acylphosphatase 60 140 1.3E-17 T 29-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 SMALA_RS07440 7738541fdc08cd7a16625123643b7b07 349 SUPERFAMILY SSF51679 1 338 1.7E-70 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS07440 7738541fdc08cd7a16625123643b7b07 349 Pfam PF00296 Luciferase-like monooxygenase 17 318 1.1E-78 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS07440 7738541fdc08cd7a16625123643b7b07 349 Gene3D G3DSA:3.20.20.30 1 343 1.2E-71 T 29-03-2018 SMALA_RS07440 7738541fdc08cd7a16625123643b7b07 349 TIGRFAM TIGR03559 F420_Rv3520c: probable F420-dependent oxidoreductase, Rv3520c family 2 322 8.4E-122 T 29-03-2018 IPR019951 F420-dependent oxidoreductase-predicted, Rv3520c SMALA_RS14440 8e5e2b433e7033b87e4a43405e299189 240 SUPERFAMILY SSF52172 4 175 1.17E-35 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS14440 8e5e2b433e7033b87e4a43405e299189 240 Pfam PF00072 Response regulator receiver domain 7 114 8.8E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS14440 8e5e2b433e7033b87e4a43405e299189 240 Gene3D G3DSA:1.10.10.10 130 240 9.7E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS14440 8e5e2b433e7033b87e4a43405e299189 240 SMART SM00448 5 115 2.3E-32 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS14440 8e5e2b433e7033b87e4a43405e299189 240 SMART SM00862 158 233 2.2E-23 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS14440 8e5e2b433e7033b87e4a43405e299189 240 Pfam PF00486 Transcriptional regulatory protein, C terminal 160 231 7.8E-22 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS14440 8e5e2b433e7033b87e4a43405e299189 240 Gene3D G3DSA:3.40.50.2300 4 129 6.4E-34 T 29-03-2018 SMALA_RS36395 cf3640595ebfda5e2a75c19a0652cb3c 272 Gene3D G3DSA:1.10.1740.10 39 116 8.0E-18 T 29-03-2018 SMALA_RS36395 cf3640595ebfda5e2a75c19a0652cb3c 272 SUPERFAMILY SSF88659 187 266 1.35E-15 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS36395 cf3640595ebfda5e2a75c19a0652cb3c 272 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 43 267 6.3E-83 T 29-03-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS36395 cf3640595ebfda5e2a75c19a0652cb3c 272 Pfam PF04539 Sigma-70 region 3 129 190 2.6E-8 T 29-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS36395 cf3640595ebfda5e2a75c19a0652cb3c 272 Pfam PF04545 Sigma-70, region 4 217 265 2.9E-17 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS36395 cf3640595ebfda5e2a75c19a0652cb3c 272 Pfam PF04542 Sigma-70 region 2 50 118 3.7E-15 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS36395 cf3640595ebfda5e2a75c19a0652cb3c 272 PRINTS PR00046 Major sigma-70 factor signature 73 86 8.6E-7 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS36395 cf3640595ebfda5e2a75c19a0652cb3c 272 PRINTS PR00046 Major sigma-70 factor signature 220 232 8.6E-7 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS36395 cf3640595ebfda5e2a75c19a0652cb3c 272 PRINTS PR00046 Major sigma-70 factor signature 237 252 8.6E-7 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS36395 cf3640595ebfda5e2a75c19a0652cb3c 272 Gene3D G3DSA:1.10.10.10 190 272 9.9E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS36395 cf3640595ebfda5e2a75c19a0652cb3c 272 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 46 266 8.3E-31 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS36395 cf3640595ebfda5e2a75c19a0652cb3c 272 SUPERFAMILY SSF88946 40 118 1.06E-23 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS36395 cf3640595ebfda5e2a75c19a0652cb3c 272 Gene3D G3DSA:1.10.10.10 119 172 1.1E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS36395 cf3640595ebfda5e2a75c19a0652cb3c 272 SUPERFAMILY SSF88659 122 198 5.23E-12 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS10470 011c2fc177bc526e0dc88d903baa28c4 380 Gene3D G3DSA:3.40.50.2000 26 190 6.1E-4 T 29-03-2018 SMALA_RS10470 011c2fc177bc526e0dc88d903baa28c4 380 SUPERFAMILY SSF53756 5 379 6.67E-75 T 29-03-2018 SMALA_RS10470 011c2fc177bc526e0dc88d903baa28c4 380 Gene3D G3DSA:3.40.50.2000 191 365 1.1E-51 T 29-03-2018 SMALA_RS10470 011c2fc177bc526e0dc88d903baa28c4 380 Pfam PF13439 Glycosyltransferase Family 4 16 178 4.4E-8 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 SMALA_RS10470 011c2fc177bc526e0dc88d903baa28c4 380 Pfam PF00534 Glycosyl transferases group 1 191 362 7.3E-44 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 SMALA_RS22090 e56aedf6ddd7c45ca6261097c1d5f25f 260 Gene3D G3DSA:3.10.180.10 13 132 8.7E-17 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS22090 e56aedf6ddd7c45ca6261097c1d5f25f 260 SUPERFAMILY SSF54593 137 255 4.16E-16 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS22090 e56aedf6ddd7c45ca6261097c1d5f25f 260 SUPERFAMILY SSF54593 11 174 4.81E-20 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS22090 e56aedf6ddd7c45ca6261097c1d5f25f 260 Gene3D G3DSA:3.10.180.10 133 255 1.1E-12 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS22090 e56aedf6ddd7c45ca6261097c1d5f25f 260 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 16 119 1.4E-5 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMALA_RS00475 4a77e0c97c114a7b84a2a9611e68648f 654 Pfam PF00931 NB-ARC domain 310 507 9.0E-12 T 29-03-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207 SMALA_RS00475 4a77e0c97c114a7b84a2a9611e68648f 654 SMART SM00862 15 87 3.4E-7 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS00475 4a77e0c97c114a7b84a2a9611e68648f 654 Gene3D G3DSA:1.10.10.10 6 96 6.7E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS00475 4a77e0c97c114a7b84a2a9611e68648f 654 Gene3D G3DSA:1.25.40.10 97 269 1.8E-18 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS00475 4a77e0c97c114a7b84a2a9611e68648f 654 Pfam PF03704 Bacterial transcriptional activator domain 94 239 7.0E-36 T 29-03-2018 IPR005158 Bacterial transcriptional activator domain SMALA_RS00475 4a77e0c97c114a7b84a2a9611e68648f 654 SMART SM01043 94 239 3.8E-36 T 29-03-2018 IPR005158 Bacterial transcriptional activator domain SMALA_RS00475 4a77e0c97c114a7b84a2a9611e68648f 654 PRINTS PR00364 Disease resistance protein signature 391 405 2.2E-9 T 29-03-2018 SMALA_RS00475 4a77e0c97c114a7b84a2a9611e68648f 654 PRINTS PR00364 Disease resistance protein signature 476 490 2.2E-9 T 29-03-2018 SMALA_RS00475 4a77e0c97c114a7b84a2a9611e68648f 654 PRINTS PR00364 Disease resistance protein signature 314 329 2.2E-9 T 29-03-2018 SMALA_RS00475 4a77e0c97c114a7b84a2a9611e68648f 654 SUPERFAMILY SSF52540 278 510 2.85E-22 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS00475 4a77e0c97c114a7b84a2a9611e68648f 654 Pfam PF00486 Transcriptional regulatory protein, C terminal 22 82 3.0E-6 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS00475 4a77e0c97c114a7b84a2a9611e68648f 654 SUPERFAMILY SSF46894 3 87 5.67E-11 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS00475 4a77e0c97c114a7b84a2a9611e68648f 654 Gene3D G3DSA:1.10.10.10 495 648 4.1E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS00475 4a77e0c97c114a7b84a2a9611e68648f 654 Gene3D G3DSA:3.40.50.300 274 439 2.0E-15 T 29-03-2018 SMALA_RS00475 4a77e0c97c114a7b84a2a9611e68648f 654 SUPERFAMILY SSF48452 91 251 1.78E-27 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS14285 3b053b6b3d047eaebb53ecebc1a183c1 232 SUPERFAMILY SSF51735 5 227 4.77E-55 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS14285 3b053b6b3d047eaebb53ecebc1a183c1 232 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMALA_RS14285 3b053b6b3d047eaebb53ecebc1a183c1 232 Gene3D G3DSA:3.40.50.720 141 230 1.4E-13 T 29-03-2018 SMALA_RS14285 3b053b6b3d047eaebb53ecebc1a183c1 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 1.6E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS14285 3b053b6b3d047eaebb53ecebc1a183c1 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 1.6E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS14285 3b053b6b3d047eaebb53ecebc1a183c1 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 1.6E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS14285 3b053b6b3d047eaebb53ecebc1a183c1 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 120 136 1.6E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS14285 3b053b6b3d047eaebb53ecebc1a183c1 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 1.6E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS14285 3b053b6b3d047eaebb53ecebc1a183c1 232 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 72 83 8.0E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS14285 3b053b6b3d047eaebb53ecebc1a183c1 232 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 8.0E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS14285 3b053b6b3d047eaebb53ecebc1a183c1 232 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 126 134 8.0E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS14285 3b053b6b3d047eaebb53ecebc1a183c1 232 Gene3D G3DSA:3.40.50.720 2 139 1.0E-40 T 29-03-2018 SMALA_RS14285 3b053b6b3d047eaebb53ecebc1a183c1 232 Pfam PF00106 short chain dehydrogenase 4 196 3.7E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS02430 d68d94505cda2bfcddcf3266deee9361 407 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 11 33 7.3E-10 T 29-03-2018 SMALA_RS02430 d68d94505cda2bfcddcf3266deee9361 407 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 289 304 7.3E-10 T 29-03-2018 SMALA_RS02430 d68d94505cda2bfcddcf3266deee9361 407 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 304 320 7.3E-10 T 29-03-2018 SMALA_RS02430 d68d94505cda2bfcddcf3266deee9361 407 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 155 170 7.3E-10 T 29-03-2018 SMALA_RS02430 d68d94505cda2bfcddcf3266deee9361 407 Pfam PF01494 FAD binding domain 11 346 1.8E-12 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 SMALA_RS02430 d68d94505cda2bfcddcf3266deee9361 407 SUPERFAMILY SSF51905 11 176 3.82E-50 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS02430 d68d94505cda2bfcddcf3266deee9361 407 SUPERFAMILY SSF51905 276 375 3.82E-50 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS02430 d68d94505cda2bfcddcf3266deee9361 407 Gene3D G3DSA:3.50.50.60 8 361 1.3E-36 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS22450 5bd22c9a5db704bd4071d110cd18d341 129 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 129 3.3E-46 T 29-03-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS22450 5bd22c9a5db704bd4071d110cd18d341 129 Gene3D G3DSA:3.30.1390.10 59 129 1.1E-28 T 29-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like SMALA_RS22450 5bd22c9a5db704bd4071d110cd18d341 129 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 63 129 5.8E-28 T 29-03-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS22450 5bd22c9a5db704bd4071d110cd18d341 129 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 7 53 9.9E-18 T 29-03-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS22450 5bd22c9a5db704bd4071d110cd18d341 129 SUPERFAMILY SSF54736 58 129 1.55E-22 T 29-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like SMALA_RS22450 5bd22c9a5db704bd4071d110cd18d341 129 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 64 129 3.0E-20 T 29-03-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS22450 5bd22c9a5db704bd4071d110cd18d341 129 Gene3D G3DSA:1.20.5.710 4 58 5.8E-15 T 29-03-2018 SMALA_RS22450 5bd22c9a5db704bd4071d110cd18d341 129 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 3 129 22.847 T 29-03-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS22450 5bd22c9a5db704bd4071d110cd18d341 129 SUPERFAMILY SSF48300 5 65 1.83E-14 T 29-03-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS23080 00b63453324bea2467b360f4ebee531a 749 Gene3D G3DSA:3.30.470.20 616 748 1.4E-29 T 29-03-2018 SMALA_RS23080 00b63453324bea2467b360f4ebee531a 749 SMART SM00881 64 159 1.4E-16 T 29-03-2018 IPR003781 CoA-binding GO:0048037 SMALA_RS23080 00b63453324bea2467b360f4ebee531a 749 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 206 340 4.0E-43 T 29-03-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain SMALA_RS23080 00b63453324bea2467b360f4ebee531a 749 Gene3D G3DSA:3.40.50.261 188 341 5.5E-27 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMALA_RS23080 00b63453324bea2467b360f4ebee531a 749 SUPERFAMILY SSF56059 536 747 1.04E-39 T 29-03-2018 SMALA_RS23080 00b63453324bea2467b360f4ebee531a 749 Gene3D G3DSA:3.40.50.720 60 187 1.9E-28 T 29-03-2018 SMALA_RS23080 00b63453324bea2467b360f4ebee531a 749 SUPERFAMILY SSF52210 346 503 7.98E-25 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMALA_RS23080 00b63453324bea2467b360f4ebee531a 749 SUPERFAMILY SSF51735 61 189 4.28E-23 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS23080 00b63453324bea2467b360f4ebee531a 749 SUPERFAMILY SSF52210 200 342 9.81E-32 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMALA_RS23080 00b63453324bea2467b360f4ebee531a 749 Gene3D G3DSA:3.40.50.261 343 510 5.7E-24 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMALA_RS23080 00b63453324bea2467b360f4ebee531a 749 Pfam PF13549 ATP-grasp domain 533 744 2.7E-62 T 29-03-2018 SMALA_RS23080 00b63453324bea2467b360f4ebee531a 749 Pfam PF13380 CoA binding domain 69 189 9.1E-14 T 29-03-2018 IPR003781 CoA-binding GO:0048037 SMALA_RS23080 00b63453324bea2467b360f4ebee531a 749 Gene3D G3DSA:3.30.1490.20 555 615 4.9E-21 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SMALA_RS15315 7c87150d505eb4f077f078e44f8e610d 299 Gene3D G3DSA:3.30.465.10 63 175 3.2E-26 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SMALA_RS15315 7c87150d505eb4f077f078e44f8e610d 299 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 12 175 1.8E-40 T 29-03-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 SMALA_RS15315 7c87150d505eb4f077f078e44f8e610d 299 SUPERFAMILY SSF55447 181 230 4.08E-5 T 29-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal SMALA_RS15315 7c87150d505eb4f077f078e44f8e610d 299 Gene3D G3DSA:3.30.390.50 178 299 1.8E-23 T 29-03-2018 SMALA_RS15315 7c87150d505eb4f077f078e44f8e610d 299 Gene3D G3DSA:3.30.43.10 14 60 1.7E-13 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 SMALA_RS15315 7c87150d505eb4f077f078e44f8e610d 299 SUPERFAMILY SSF56176 9 175 1.13E-39 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SMALA_RS33510 8549edfcd38ccf61f504aa8125017310 2404 Pfam PF13193 AMP-binding enzyme C-terminal domain 872 947 3.9E-12 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS33510 8549edfcd38ccf61f504aa8125017310 2404 Pfam PF13193 AMP-binding enzyme C-terminal domain 1941 2012 3.0E-10 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS33510 8549edfcd38ccf61f504aa8125017310 2404 SUPERFAMILY SSF52777 16 192 5.89E-39 T 29-03-2018 SMALA_RS33510 8549edfcd38ccf61f504aa8125017310 2404 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1671 1682 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS33510 8549edfcd38ccf61f504aa8125017310 2404 Gene3D G3DSA:3.30.300.30 859 974 2.9E-36 T 29-03-2018 SMALA_RS33510 8549edfcd38ccf61f504aa8125017310 2404 Gene3D G3DSA:3.30.300.30 1928 2039 3.3E-33 T 29-03-2018 SMALA_RS33510 8549edfcd38ccf61f504aa8125017310 2404 SUPERFAMILY SSF47336 965 1036 3.53E-19 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS33510 8549edfcd38ccf61f504aa8125017310 2404 Gene3D G3DSA:3.40.50.980 621 777 5.6E-37 T 29-03-2018 SMALA_RS33510 8549edfcd38ccf61f504aa8125017310 2404 ProSitePatterns PS00012 Phosphopantetheine attachment site. 995 1010 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS33510 8549edfcd38ccf61f504aa8125017310 2404 Gene3D G3DSA:2.30.38.10 778 857 9.2E-24 T 29-03-2018 SMALA_RS33510 8549edfcd38ccf61f504aa8125017310 2404 Gene3D G3DSA:2.30.38.10 1843 1926 2.8E-24 T 29-03-2018 SMALA_RS33510 8549edfcd38ccf61f504aa8125017310 2404 SUPERFAMILY SSF53474 2104 2376 3.6E-53 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS33510 8549edfcd38ccf61f504aa8125017310 2404 Pfam PF00975 Thioesterase domain 2123 2373 1.5E-30 T 29-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 SMALA_RS33510 8549edfcd38ccf61f504aa8125017310 2404 Gene3D G3DSA:3.40.50.980 1519 1676 9.2E-42 T 29-03-2018 SMALA_RS33510 8549edfcd38ccf61f504aa8125017310 2404 SUPERFAMILY SSF56801 468 984 6.02E-140 T 29-03-2018 SMALA_RS33510 8549edfcd38ccf61f504aa8125017310 2404 Gene3D G3DSA:3.40.50.980 467 620 2.0E-40 T 29-03-2018 SMALA_RS33510 8549edfcd38ccf61f504aa8125017310 2404 SUPERFAMILY SSF47336 2030 2101 1.44E-18 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS33510 8549edfcd38ccf61f504aa8125017310 2404 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 495 887 3.9E-122 T 29-03-2018 IPR010071 Amino acid adenylation domain SMALA_RS33510 8549edfcd38ccf61f504aa8125017310 2404 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1549 1957 2.2E-119 T 29-03-2018 IPR010071 Amino acid adenylation domain SMALA_RS33510 8549edfcd38ccf61f504aa8125017310 2404 Gene3D G3DSA:3.40.50.980 1677 1838 8.3E-27 T 29-03-2018 SMALA_RS33510 8549edfcd38ccf61f504aa8125017310 2404 SMART SM00823 Phosphopantetheine attachment site 2036 2105 1.2E-5 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS33510 8549edfcd38ccf61f504aa8125017310 2404 SMART SM00823 Phosphopantetheine attachment site 971 1040 8.6E-4 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS33510 8549edfcd38ccf61f504aa8125017310 2404 SUPERFAMILY SSF56801 1505 2049 1.83E-136 T 29-03-2018 SMALA_RS33510 8549edfcd38ccf61f504aa8125017310 2404 Gene3D G3DSA:3.30.559.10 1042 1261 1.1E-48 T 29-03-2018 SMALA_RS33510 8549edfcd38ccf61f504aa8125017310 2404 Pfam PF00501 AMP-binding enzyme 1527 1933 1.0E-84 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS33510 8549edfcd38ccf61f504aa8125017310 2404 Pfam PF00501 AMP-binding enzyme 474 864 1.3E-90 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS33510 8549edfcd38ccf61f504aa8125017310 2404 Gene3D G3DSA:1.10.1200.10 2040 2109 1.0E-23 T 29-03-2018 SMALA_RS33510 8549edfcd38ccf61f504aa8125017310 2404 Gene3D G3DSA:1.10.1200.10 975 1041 7.6E-22 T 29-03-2018 SMALA_RS33510 8549edfcd38ccf61f504aa8125017310 2404 Pfam PF00550 Phosphopantetheine attachment site 2038 2101 1.4E-15 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS33510 8549edfcd38ccf61f504aa8125017310 2404 Pfam PF00550 Phosphopantetheine attachment site 974 1032 2.0E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS33510 8549edfcd38ccf61f504aa8125017310 2404 Pfam PF00668 Condensation domain 11 447 1.6E-80 T 29-03-2018 IPR001242 Condensation domain SMALA_RS33510 8549edfcd38ccf61f504aa8125017310 2404 Pfam PF00668 Condensation domain 1056 1504 6.6E-91 T 29-03-2018 IPR001242 Condensation domain SMALA_RS33510 8549edfcd38ccf61f504aa8125017310 2404 ProSitePatterns PS00455 Putative AMP-binding domain signature. 618 629 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS33510 8549edfcd38ccf61f504aa8125017310 2404 Gene3D G3DSA:3.40.50.1820 2110 2381 2.5E-22 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS33510 8549edfcd38ccf61f504aa8125017310 2404 SUPERFAMILY SSF52777 1242 1492 8.12E-59 T 29-03-2018 SMALA_RS33510 8549edfcd38ccf61f504aa8125017310 2404 SUPERFAMILY SSF52777 194 443 3.22E-53 T 29-03-2018 SMALA_RS33510 8549edfcd38ccf61f504aa8125017310 2404 Gene3D G3DSA:3.30.559.10 4 254 3.0E-39 T 29-03-2018 SMALA_RS33510 8549edfcd38ccf61f504aa8125017310 2404 SUPERFAMILY SSF52777 1058 1229 1.56E-51 T 29-03-2018 SMALA_RS31585 db066f8c034c7d71b843ae9edc91e439 177 SMART SM00347 48 151 1.6E-16 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS31585 db066f8c034c7d71b843ae9edc91e439 177 SUPERFAMILY SSF46785 17 162 5.97E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS31585 db066f8c034c7d71b843ae9edc91e439 177 PRINTS PR00598 Bacterial regulatory protein MarR family signature 92 107 7.3E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS31585 db066f8c034c7d71b843ae9edc91e439 177 PRINTS PR00598 Bacterial regulatory protein MarR family signature 111 127 7.3E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS31585 db066f8c034c7d71b843ae9edc91e439 177 PRINTS PR00598 Bacterial regulatory protein MarR family signature 141 161 7.3E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS31585 db066f8c034c7d71b843ae9edc91e439 177 Gene3D G3DSA:1.10.10.10 4 170 2.7E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS31585 db066f8c034c7d71b843ae9edc91e439 177 Pfam PF12802 MarR family 53 115 3.3E-13 T 29-03-2018 SMALA_RS02640 395fdfd9dfa467daeafad1239d45f7f6 329 Pfam PF00356 Bacterial regulatory proteins, lacI family 1 40 4.8E-13 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS02640 395fdfd9dfa467daeafad1239d45f7f6 329 Gene3D G3DSA:3.40.50.2300 48 171 5.4E-27 T 29-03-2018 SMALA_RS02640 395fdfd9dfa467daeafad1239d45f7f6 329 Pfam PF13377 Periplasmic binding protein-like domain 165 319 7.1E-35 T 29-03-2018 SMALA_RS02640 395fdfd9dfa467daeafad1239d45f7f6 329 SUPERFAMILY SSF53822 52 323 6.48E-61 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SMALA_RS02640 395fdfd9dfa467daeafad1239d45f7f6 329 SUPERFAMILY SSF47413 1 43 8.45E-11 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS02640 395fdfd9dfa467daeafad1239d45f7f6 329 SMART SM00354 1 62 3.5E-19 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS02640 395fdfd9dfa467daeafad1239d45f7f6 329 Gene3D G3DSA:3.40.50.2300 172 325 4.7E-41 T 29-03-2018 SMALA_RS02640 395fdfd9dfa467daeafad1239d45f7f6 329 Gene3D G3DSA:1.10.260.40 1 47 4.5E-15 T 29-03-2018 SMALA_RS09825 86fba18718d30b01d934c8ee0f9e1256 238 SUPERFAMILY SSF52540 4 236 4.88E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS09825 86fba18718d30b01d934c8ee0f9e1256 238 Gene3D G3DSA:3.40.50.300 1 237 1.1E-57 T 29-03-2018 SMALA_RS09825 86fba18718d30b01d934c8ee0f9e1256 238 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS09825 86fba18718d30b01d934c8ee0f9e1256 238 SMART SM00382 29 216 9.8E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS09825 86fba18718d30b01d934c8ee0f9e1256 238 PIRSF PIRSF039137 1 238 8.7E-110 T 29-03-2018 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein GO:0015658|GO:0015803 SMALA_RS09825 86fba18718d30b01d934c8ee0f9e1256 238 Pfam PF00005 ABC transporter 21 165 8.3E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS39470 f89db767930861c7dc3066c92b2e52f5 371 Gene3D G3DSA:3.90.180.10 6 178 2.6E-31 T 29-03-2018 SMALA_RS39470 f89db767930861c7dc3066c92b2e52f5 371 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 30 148 6.4E-24 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS39470 f89db767930861c7dc3066c92b2e52f5 371 Pfam PF00107 Zinc-binding dehydrogenase 197 326 4.7E-19 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMALA_RS39470 f89db767930861c7dc3066c92b2e52f5 371 SUPERFAMILY SSF51735 157 330 1.06E-28 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS39470 f89db767930861c7dc3066c92b2e52f5 371 SMART SM00829 11 366 0.0085 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS39470 f89db767930861c7dc3066c92b2e52f5 371 Gene3D G3DSA:3.40.50.10730 179 328 5.5E-24 T 29-03-2018 SMALA_RS39470 f89db767930861c7dc3066c92b2e52f5 371 SUPERFAMILY SSF50129 6 192 3.5E-36 T 29-03-2018 IPR011032 GroES-like SMALA_RS16175 b2783bf1e4d0e58a918e7455ac066de6 260 SUPERFAMILY SSF52540 21 237 6.81E-68 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS16175 b2783bf1e4d0e58a918e7455ac066de6 260 Pfam PF00005 ABC transporter 38 184 6.6E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS16175 b2783bf1e4d0e58a918e7455ac066de6 260 SMART SM00382 47 233 2.4E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS16175 b2783bf1e4d0e58a918e7455ac066de6 260 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS16175 b2783bf1e4d0e58a918e7455ac066de6 260 Gene3D G3DSA:3.40.50.300 15 256 5.1E-59 T 29-03-2018 SMALA_RS03060 9f036ad518819698f5e73ce9fa3175a8 435 Pfam PF01590 GAF domain 104 218 1.6E-8 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS03060 9f036ad518819698f5e73ce9fa3175a8 435 Gene3D G3DSA:3.30.530.20 272 412 2.2E-4 T 29-03-2018 IPR023393 START-like domain SMALA_RS25985 b0798e5c3ec7c7bc59c18f6c8c5f02ad 918 TIGRFAM TIGR00374 TIGR00374: TIGR00374 family protein 641 913 2.4E-13 T 29-03-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD SMALA_RS25985 b0798e5c3ec7c7bc59c18f6c8c5f02ad 918 SUPERFAMILY SSF56112 351 452 2.56E-8 T 29-03-2018 IPR011009 Protein kinase-like domain SMALA_RS25985 b0798e5c3ec7c7bc59c18f6c8c5f02ad 918 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 619 905 3.2E-32 T 29-03-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD SMALA_RS25985 b0798e5c3ec7c7bc59c18f6c8c5f02ad 918 Gene3D G3DSA:1.10.510.10 307 735 2.4E-6 T 29-03-2018 SMALA_RS12660 d244b89460415a12de54a38f807877e1 386 Gene3D G3DSA:1.10.1200.80 270 347 1.8E-17 T 29-03-2018 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 SMALA_RS12660 d244b89460415a12de54a38f807877e1 386 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 108 126 - T 29-03-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 SMALA_RS12660 d244b89460415a12de54a38f807877e1 386 Pfam PF01207 Dihydrouridine synthase (Dus) 24 333 3.7E-94 T 29-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 SMALA_RS12660 d244b89460415a12de54a38f807877e1 386 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 14 336 1.6E-109 T 29-03-2018 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 SMALA_RS12660 d244b89460415a12de54a38f807877e1 386 PIRSF PIRSF006621 11 347 6.2E-101 T 29-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 SMALA_RS12660 d244b89460415a12de54a38f807877e1 386 SUPERFAMILY SSF51395 21 335 5.13E-78 T 29-03-2018 SMALA_RS12660 d244b89460415a12de54a38f807877e1 386 Gene3D G3DSA:3.20.20.70 18 257 1.0E-54 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS10715 15d21f555808a2ef5d2b1da63bd72b3b 271 Hamap MF_00013 Octanoyltransferase [lipB]. 14 264 32.558 T 29-03-2018 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 SMALA_RS10715 15d21f555808a2ef5d2b1da63bd72b3b 271 Gene3D G3DSA:3.30.930.10 18 262 2.8E-74 T 29-03-2018 SMALA_RS10715 15d21f555808a2ef5d2b1da63bd72b3b 271 SUPERFAMILY SSF55681 25 143 7.87E-62 T 29-03-2018 SMALA_RS10715 15d21f555808a2ef5d2b1da63bd72b3b 271 SUPERFAMILY SSF55681 189 263 7.87E-62 T 29-03-2018 SMALA_RS10715 15d21f555808a2ef5d2b1da63bd72b3b 271 ProDom PD006086 LIGASE LIPOATE-PROTEIN B TRANSFERASE ACYLTRANSFERASE LIPOYLTRANSFERASE LIPOYL-ACYL-CARRIER 2.3.1.- PROTEIN-PROTEIN- N-LIPOYLTRANSFERASE 88 140 3.0E-22 T 29-03-2018 SMALA_RS10715 15d21f555808a2ef5d2b1da63bd72b3b 271 PIRSF PIRSF016262 13 267 1.4E-57 T 29-03-2018 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 SMALA_RS10715 15d21f555808a2ef5d2b1da63bd72b3b 271 ProSitePatterns PS01313 Lipoate-protein ligase B signature. 84 99 - T 29-03-2018 IPR020605 Octanoyltransferase, conserved site GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 SMALA_RS37380 5eb60e3cc3084f3eb0a9e94c3e51117c 792 SUPERFAMILY SSF56784 552 762 3.08E-53 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS37380 5eb60e3cc3084f3eb0a9e94c3e51117c 792 SUPERFAMILY SSF56784 458 478 3.08E-53 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS37380 5eb60e3cc3084f3eb0a9e94c3e51117c 792 Pfam PF00702 haloacid dehalogenase-like hydrolase 456 676 2.2E-41 T 29-03-2018 SMALA_RS37380 5eb60e3cc3084f3eb0a9e94c3e51117c 792 SUPERFAMILY SSF55008 15 86 2.75E-17 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 SMALA_RS37380 5eb60e3cc3084f3eb0a9e94c3e51117c 792 Gene3D G3DSA:3.40.1110.10 476 589 6.8E-26 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 SMALA_RS37380 5eb60e3cc3084f3eb0a9e94c3e51117c 792 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 685 697 2.4E-22 T 29-03-2018 SMALA_RS37380 5eb60e3cc3084f3eb0a9e94c3e51117c 792 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 609 619 2.4E-22 T 29-03-2018 SMALA_RS37380 5eb60e3cc3084f3eb0a9e94c3e51117c 792 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 662 681 2.4E-22 T 29-03-2018 SMALA_RS37380 5eb60e3cc3084f3eb0a9e94c3e51117c 792 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 310 324 2.4E-22 T 29-03-2018 SMALA_RS37380 5eb60e3cc3084f3eb0a9e94c3e51117c 792 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 460 474 2.4E-22 T 29-03-2018 SMALA_RS37380 5eb60e3cc3084f3eb0a9e94c3e51117c 792 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 179 764 1.6E-169 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 SMALA_RS37380 5eb60e3cc3084f3eb0a9e94c3e51117c 792 Pfam PF00403 Heavy-metal-associated domain 24 80 3.5E-11 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 SMALA_RS37380 5eb60e3cc3084f3eb0a9e94c3e51117c 792 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 462 468 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 SMALA_RS37380 5eb60e3cc3084f3eb0a9e94c3e51117c 792 ProSitePatterns PS01229 Hypothetical cof family signature 2. 662 684 - T 29-03-2018 SMALA_RS37380 5eb60e3cc3084f3eb0a9e94c3e51117c 792 Pfam PF00122 E1-E2 ATPase 261 439 1.5E-48 T 29-03-2018 SMALA_RS37380 5eb60e3cc3084f3eb0a9e94c3e51117c 792 SUPERFAMILY SSF81653 266 360 7.19E-22 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 SMALA_RS37380 5eb60e3cc3084f3eb0a9e94c3e51117c 792 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 239 740 1.5E-75 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMALA_RS37380 5eb60e3cc3084f3eb0a9e94c3e51117c 792 ProSitePatterns PS01047 Heavy-metal-associated domain. 24 52 - T 29-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 SMALA_RS37380 5eb60e3cc3084f3eb0a9e94c3e51117c 792 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 218 765 4.3E-142 T 29-03-2018 SMALA_RS37380 5eb60e3cc3084f3eb0a9e94c3e51117c 792 Gene3D G3DSA:3.40.50.1000 590 726 5.7E-36 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS37380 5eb60e3cc3084f3eb0a9e94c3e51117c 792 Gene3D G3DSA:3.30.70.100 18 86 3.9E-18 T 29-03-2018 SMALA_RS37380 5eb60e3cc3084f3eb0a9e94c3e51117c 792 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 662 678 3.3E-6 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMALA_RS37380 5eb60e3cc3084f3eb0a9e94c3e51117c 792 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 634 650 3.3E-6 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMALA_RS37380 5eb60e3cc3084f3eb0a9e94c3e51117c 792 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 693 718 3.3E-6 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMALA_RS37380 5eb60e3cc3084f3eb0a9e94c3e51117c 792 Gene3D G3DSA:1.20.1110.10 223 475 4.6E-43 T 29-03-2018 SMALA_RS05270 33e7648b47452b1afa1f46b8fee48c45 1034 SUPERFAMILY SSF74650 684 1028 2.86E-57 T 29-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 SMALA_RS05270 33e7648b47452b1afa1f46b8fee48c45 1034 SUPERFAMILY SSF88688 520 618 2.13E-27 T 29-03-2018 IPR028995 Glycoside hydrolase families 57/38, central domain SMALA_RS05270 33e7648b47452b1afa1f46b8fee48c45 1034 Gene3D G3DSA:3.20.110.10 203 465 2.6E-80 T 29-03-2018 IPR027291 Glycoside hydrolase 38/57, N-terminal domain SMALA_RS05270 33e7648b47452b1afa1f46b8fee48c45 1034 Pfam PF07748 Glycosyl hydrolases family 38 C-terminal domain 675 1025 1.9E-62 T 29-03-2018 IPR011682 Glycosyl hydrolase family 38, C-terminal GO:0004559|GO:0006013 SMALA_RS05270 33e7648b47452b1afa1f46b8fee48c45 1034 Pfam PF01074 Glycosyl hydrolases family 38 N-terminal domain 254 514 3.8E-84 T 29-03-2018 IPR000602 Glycoside hydrolase family 38, N-terminal domain GO:0004559|GO:0006013 SMALA_RS05270 33e7648b47452b1afa1f46b8fee48c45 1034 SMART SM00872 521 599 6.3E-40 T 29-03-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 SMALA_RS05270 33e7648b47452b1afa1f46b8fee48c45 1034 SUPERFAMILY SSF88713 250 519 9.34E-77 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 SMALA_RS05270 33e7648b47452b1afa1f46b8fee48c45 1034 Pfam PF09261 Alpha mannosidase middle domain 521 599 2.5E-27 T 29-03-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 SMALA_RS05270 33e7648b47452b1afa1f46b8fee48c45 1034 Gene3D G3DSA:1.20.1270.50 520 621 3.8E-32 T 29-03-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 SMALA_RS40420 0f5e9ea833e50d5ae89e9db5d04a0166 515 SUPERFAMILY SSF52540 273 485 1.52E-42 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS40420 0f5e9ea833e50d5ae89e9db5d04a0166 515 SMART SM00382 32 219 2.9E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS40420 0f5e9ea833e50d5ae89e9db5d04a0166 515 SMART SM00382 282 502 2.8E-5 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS40420 0f5e9ea833e50d5ae89e9db5d04a0166 515 Gene3D G3DSA:3.40.50.300 4 237 2.0E-46 T 29-03-2018 SMALA_RS40420 0f5e9ea833e50d5ae89e9db5d04a0166 515 Gene3D G3DSA:3.40.50.300 262 511 1.4E-34 T 29-03-2018 SMALA_RS40420 0f5e9ea833e50d5ae89e9db5d04a0166 515 ProSitePatterns PS00211 ABC transporters family signature. 400 414 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS40420 0f5e9ea833e50d5ae89e9db5d04a0166 515 SUPERFAMILY SSF52540 6 228 2.09E-51 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS40420 0f5e9ea833e50d5ae89e9db5d04a0166 515 Pfam PF00005 ABC transporter 23 171 2.5E-23 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS40420 0f5e9ea833e50d5ae89e9db5d04a0166 515 Pfam PF00005 ABC transporter 274 427 2.8E-19 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS28210 c9b2da6ffd99749ca4ea7e5388465e7a 277 SUPERFAMILY SSF88659 186 274 6.17E-25 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS28210 c9b2da6ffd99749ca4ea7e5388465e7a 277 Pfam PF04539 Sigma-70 region 3 127 207 3.5E-7 T 29-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS28210 c9b2da6ffd99749ca4ea7e5388465e7a 277 PRINTS PR00046 Major sigma-70 factor signature 225 237 2.0E-12 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS28210 c9b2da6ffd99749ca4ea7e5388465e7a 277 PRINTS PR00046 Major sigma-70 factor signature 257 268 2.0E-12 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS28210 c9b2da6ffd99749ca4ea7e5388465e7a 277 PRINTS PR00046 Major sigma-70 factor signature 74 87 2.0E-12 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS28210 c9b2da6ffd99749ca4ea7e5388465e7a 277 PRINTS PR00046 Major sigma-70 factor signature 242 257 2.0E-12 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS28210 c9b2da6ffd99749ca4ea7e5388465e7a 277 PIRSF PIRSF000770 24 276 1.7E-76 T 29-03-2018 SMALA_RS28210 c9b2da6ffd99749ca4ea7e5388465e7a 277 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 242 268 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS28210 c9b2da6ffd99749ca4ea7e5388465e7a 277 Gene3D G3DSA:1.10.10.10 120 167 2.7E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS28210 c9b2da6ffd99749ca4ea7e5388465e7a 277 TIGRFAM TIGR02479 FliA_WhiG: RNA polymerase sigma factor, FliA/WhiG family 47 272 9.0E-88 T 29-03-2018 IPR012845 RNA polymerase sigma factor, FliA/WhiG GO:0003677|GO:0003899|GO:0006352|GO:0006355|GO:0016987 SMALA_RS28210 c9b2da6ffd99749ca4ea7e5388465e7a 277 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 74 87 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS28210 c9b2da6ffd99749ca4ea7e5388465e7a 277 Gene3D G3DSA:1.10.10.10 194 277 8.3E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS28210 c9b2da6ffd99749ca4ea7e5388465e7a 277 Gene3D G3DSA:1.10.1740.10 32 117 2.6E-21 T 29-03-2018 SMALA_RS28210 c9b2da6ffd99749ca4ea7e5388465e7a 277 Pfam PF04542 Sigma-70 region 2 47 119 1.8E-17 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS28210 c9b2da6ffd99749ca4ea7e5388465e7a 277 SUPERFAMILY SSF88946 18 119 5.34E-26 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS28210 c9b2da6ffd99749ca4ea7e5388465e7a 277 SUPERFAMILY SSF88659 120 199 9.16E-14 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS28210 c9b2da6ffd99749ca4ea7e5388465e7a 277 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 43 272 1.4E-37 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS28210 c9b2da6ffd99749ca4ea7e5388465e7a 277 Pfam PF04545 Sigma-70, region 4 221 270 5.9E-19 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS21735 60bfb8be9e7db6cb159332e5152e9148 339 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 21 37 6.7E-21 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 SMALA_RS21735 60bfb8be9e7db6cb159332e5152e9148 339 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 72 91 6.7E-21 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 SMALA_RS21735 60bfb8be9e7db6cb159332e5152e9148 339 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 151 172 6.7E-21 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 SMALA_RS21735 60bfb8be9e7db6cb159332e5152e9148 339 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 204 214 6.7E-21 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 SMALA_RS21735 60bfb8be9e7db6cb159332e5152e9148 339 Gene3D G3DSA:3.40.50.620 2 199 3.9E-63 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS21735 60bfb8be9e7db6cb159332e5152e9148 339 SUPERFAMILY SSF52374 10 335 1.69E-78 T 29-03-2018 SMALA_RS21735 60bfb8be9e7db6cb159332e5152e9148 339 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 17 26 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMALA_RS21735 60bfb8be9e7db6cb159332e5152e9148 339 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 9 335 3.1E-93 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 SMALA_RS21735 60bfb8be9e7db6cb159332e5152e9148 339 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 8 336 36.282 T 29-03-2018 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 SMALA_RS21735 60bfb8be9e7db6cb159332e5152e9148 339 Gene3D G3DSA:1.10.240.10 200 318 2.2E-27 T 29-03-2018 SMALA_RS21735 60bfb8be9e7db6cb159332e5152e9148 339 Pfam PF00579 tRNA synthetases class I (W and Y) 6 290 1.5E-66 T 29-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMALA_RS08875 b055dae274a7de370d12ce01743aaed9 213 Gene3D G3DSA:3.40.50.2300 6 131 1.2E-40 T 29-03-2018 SMALA_RS08875 b055dae274a7de370d12ce01743aaed9 213 SUPERFAMILY SSF52172 6 134 4.41E-37 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS08875 b055dae274a7de370d12ce01743aaed9 213 SUPERFAMILY SSF46894 149 211 1.29E-23 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS08875 b055dae274a7de370d12ce01743aaed9 213 ProSitePatterns PS00622 LuxR-type HTH domain signature. 166 193 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS08875 b055dae274a7de370d12ce01743aaed9 213 SMART SM00421 149 206 1.1E-28 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS08875 b055dae274a7de370d12ce01743aaed9 213 Gene3D G3DSA:1.10.10.10 132 213 5.8E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS08875 b055dae274a7de370d12ce01743aaed9 213 Pfam PF00196 Bacterial regulatory proteins, luxR family 151 206 1.1E-21 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS08875 b055dae274a7de370d12ce01743aaed9 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 182 1.8E-16 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS08875 b055dae274a7de370d12ce01743aaed9 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 182 194 1.8E-16 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS08875 b055dae274a7de370d12ce01743aaed9 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 152 166 1.8E-16 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS08875 b055dae274a7de370d12ce01743aaed9 213 SMART SM00448 7 120 7.7E-35 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS08875 b055dae274a7de370d12ce01743aaed9 213 Pfam PF00072 Response regulator receiver domain 9 120 2.3E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS36135 a4526e6834fe04b4b251b7bbed826095 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 157 2.3E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS36135 a4526e6834fe04b4b251b7bbed826095 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 95 106 2.3E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS36135 a4526e6834fe04b4b251b7bbed826095 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 169 188 2.3E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS36135 a4526e6834fe04b4b251b7bbed826095 261 Gene3D G3DSA:3.40.50.720 11 51 1.0E-4 T 29-03-2018 SMALA_RS36135 a4526e6834fe04b4b251b7bbed826095 261 Gene3D G3DSA:3.40.50.720 52 259 1.7E-56 T 29-03-2018 SMALA_RS36135 a4526e6834fe04b4b251b7bbed826095 261 SUPERFAMILY SSF51735 16 257 5.45E-71 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS36135 a4526e6834fe04b4b251b7bbed826095 261 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 156 184 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMALA_RS36135 a4526e6834fe04b4b251b7bbed826095 261 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 24 256 3.0E-61 T 29-03-2018 SMALA_RS36135 a4526e6834fe04b4b251b7bbed826095 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 19 36 3.4E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS36135 a4526e6834fe04b4b251b7bbed826095 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 95 106 3.4E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS36135 a4526e6834fe04b4b251b7bbed826095 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 143 159 3.4E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS36135 a4526e6834fe04b4b251b7bbed826095 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 224 244 3.4E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS36135 a4526e6834fe04b4b251b7bbed826095 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 190 207 3.4E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS36135 a4526e6834fe04b4b251b7bbed826095 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 188 3.4E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS38360 031c105910cae79506543dbb093c2d00 324 Gene3D G3DSA:3.60.110.10 1 303 2.7E-44 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMALA_RS38360 031c105910cae79506543dbb093c2d00 324 SUPERFAMILY SSF56317 1 302 1.44E-46 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMALA_RS38360 031c105910cae79506543dbb093c2d00 324 Pfam PF00795 Carbon-nitrogen hydrolase 5 244 2.3E-26 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMALA_RS34455 ccd98033fc5bf753f3e6a2037916aa65 316 Pfam PF12833 Helix-turn-helix domain 225 303 5.6E-20 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS34455 ccd98033fc5bf753f3e6a2037916aa65 316 SUPERFAMILY SSF46689 255 307 4.48E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS34455 ccd98033fc5bf753f3e6a2037916aa65 316 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 286 302 1.2E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SMALA_RS34455 ccd98033fc5bf753f3e6a2037916aa65 316 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 271 286 1.2E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SMALA_RS34455 ccd98033fc5bf753f3e6a2037916aa65 316 Gene3D G3DSA:1.10.10.60 179 255 5.3E-10 T 29-03-2018 SMALA_RS34455 ccd98033fc5bf753f3e6a2037916aa65 316 Pfam PF12852 Cupin 6 186 6.3E-28 T 29-03-2018 IPR032783 AraC-type transcription regulator, ligand-binding domain SMALA_RS34455 ccd98033fc5bf753f3e6a2037916aa65 316 SMART SM00342 219 302 5.4E-29 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS34455 ccd98033fc5bf753f3e6a2037916aa65 316 Gene3D G3DSA:2.60.120.280 40 178 7.2E-7 T 29-03-2018 SMALA_RS34455 ccd98033fc5bf753f3e6a2037916aa65 316 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 256 298 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 SMALA_RS34455 ccd98033fc5bf753f3e6a2037916aa65 316 SUPERFAMILY SSF46689 205 253 1.43E-7 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS34455 ccd98033fc5bf753f3e6a2037916aa65 316 Gene3D G3DSA:1.10.10.60 256 314 1.4E-14 T 29-03-2018 SMALA_RS09110 757ee16abb6e3cfa3cc52bb68bf0d25f 174 Pfam PF03780 Asp23 family, cell envelope-related function 51 160 3.7E-30 T 29-03-2018 IPR005531 Alkaline shock protein Asp23 SMALA_RS26075 debd157397c06d6341cfddc40dc9b925 173 Pfam PF00293 NUDIX domain 45 160 1.6E-11 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SMALA_RS26075 debd157397c06d6341cfddc40dc9b925 173 SUPERFAMILY SSF55811 21 162 2.17E-19 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMALA_RS26075 debd157397c06d6341cfddc40dc9b925 173 Gene3D G3DSA:3.90.79.10 14 173 3.9E-20 T 29-03-2018 SMALA_RS00860 3cadeee16eebe48a4faf5d5c1deea6c0 335 Gene3D G3DSA:3.40.50.1100 11 79 0.006 T 29-03-2018 SMALA_RS00860 3cadeee16eebe48a4faf5d5c1deea6c0 335 Gene3D G3DSA:3.40.50.1100 80 153 1.0E-29 T 29-03-2018 SMALA_RS00860 3cadeee16eebe48a4faf5d5c1deea6c0 335 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 13 320 1.8E-45 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMALA_RS00860 3cadeee16eebe48a4faf5d5c1deea6c0 335 Gene3D G3DSA:3.40.50.1100 154 335 4.0E-27 T 29-03-2018 SMALA_RS00860 3cadeee16eebe48a4faf5d5c1deea6c0 335 TIGRFAM TIGR01274 ACC_deam: 1-aminocyclopropane-1-carboxylate deaminase 3 335 7.9E-162 T 29-03-2018 IPR005965 1-aminocyclopropane-1-carboxylate deaminase GO:0008660|GO:0009310|GO:0030170 KEGG: 00270+3.5.99.7 SMALA_RS00860 3cadeee16eebe48a4faf5d5c1deea6c0 335 PIRSF PIRSF006278 1 335 1.2E-118 T 29-03-2018 IPR027278 1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase SMALA_RS00860 3cadeee16eebe48a4faf5d5c1deea6c0 335 SUPERFAMILY SSF53686 6 332 2.06E-99 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMALA_RS00460 0015ff5efa65f1ecec13875b9443e5d7 1353 Gene3D G3DSA:3.40.50.980 478 627 3.6E-32 T 29-03-2018 SMALA_RS00460 0015ff5efa65f1ecec13875b9443e5d7 1353 Pfam PF00975 Thioesterase domain 1087 1331 1.9E-17 T 29-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 SMALA_RS00460 0015ff5efa65f1ecec13875b9443e5d7 1353 SMART SM00823 Phosphopantetheine attachment site 993 1062 4.4E-5 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS00460 0015ff5efa65f1ecec13875b9443e5d7 1353 Gene3D G3DSA:3.40.50.980 628 786 1.3E-34 T 29-03-2018 SMALA_RS00460 0015ff5efa65f1ecec13875b9443e5d7 1353 Pfam PF13193 AMP-binding enzyme C-terminal domain 887 961 4.8E-10 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS00460 0015ff5efa65f1ecec13875b9443e5d7 1353 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 506 901 9.2E-100 T 29-03-2018 IPR010071 Amino acid adenylation domain SMALA_RS00460 0015ff5efa65f1ecec13875b9443e5d7 1353 Gene3D G3DSA:3.30.300.30 874 998 5.4E-33 T 29-03-2018 SMALA_RS00460 0015ff5efa65f1ecec13875b9443e5d7 1353 SUPERFAMILY SSF52777 14 197 5.78E-44 T 29-03-2018 SMALA_RS00460 0015ff5efa65f1ecec13875b9443e5d7 1353 Pfam PF00550 Phosphopantetheine attachment site 994 1058 4.5E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS00460 0015ff5efa65f1ecec13875b9443e5d7 1353 SUPERFAMILY SSF56801 447 1006 2.88E-123 T 29-03-2018 SMALA_RS00460 0015ff5efa65f1ecec13875b9443e5d7 1353 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1017 1032 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS00460 0015ff5efa65f1ecec13875b9443e5d7 1353 Pfam PF00501 AMP-binding enzyme 488 879 7.6E-80 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS00460 0015ff5efa65f1ecec13875b9443e5d7 1353 Gene3D G3DSA:1.10.1200.10 999 1072 1.4E-20 T 29-03-2018 SMALA_RS00460 0015ff5efa65f1ecec13875b9443e5d7 1353 Gene3D G3DSA:3.40.50.1820 1078 1347 2.4E-18 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS00460 0015ff5efa65f1ecec13875b9443e5d7 1353 SUPERFAMILY SSF52777 205 454 2.67E-38 T 29-03-2018 SMALA_RS00460 0015ff5efa65f1ecec13875b9443e5d7 1353 SUPERFAMILY SSF53474 1070 1344 3.93E-35 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS00460 0015ff5efa65f1ecec13875b9443e5d7 1353 Gene3D G3DSA:2.30.38.10 787 872 6.6E-18 T 29-03-2018 SMALA_RS00460 0015ff5efa65f1ecec13875b9443e5d7 1353 Gene3D G3DSA:3.30.559.10 4 220 1.9E-37 T 29-03-2018 SMALA_RS00460 0015ff5efa65f1ecec13875b9443e5d7 1353 SUPERFAMILY SSF47336 990 1059 2.22E-16 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS00460 0015ff5efa65f1ecec13875b9443e5d7 1353 Pfam PF00668 Condensation domain 10 461 6.1E-63 T 29-03-2018 IPR001242 Condensation domain SMALA_RS00460 0015ff5efa65f1ecec13875b9443e5d7 1353 SMART SM00824 Thioesterase 1089 1342 5.3E-4 T 29-03-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 SMALA_RS32520 cc2e8a5f0b2abd0f1b245c32b5fa5797 275 Pfam PF12697 Alpha/beta hydrolase family 35 267 1.7E-17 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS32520 cc2e8a5f0b2abd0f1b245c32b5fa5797 275 SUPERFAMILY SSF53474 11 273 3.02E-50 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS32520 cc2e8a5f0b2abd0f1b245c32b5fa5797 275 Gene3D G3DSA:3.40.50.1820 12 274 1.4E-40 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS06870 2921776d026a97f2ea963913d1feb23e 1762 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 573 872 5.6E-100 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS06870 2921776d026a97f2ea963913d1feb23e 1762 SMART SM00826 939 1105 6.5E-81 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS06870 2921776d026a97f2ea963913d1feb23e 1762 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1401 1581 1.5E-56 T 29-03-2018 SMALA_RS06870 2921776d026a97f2ea963913d1feb23e 1762 Gene3D G3DSA:1.10.1200.10 1665 1758 1.8E-17 T 29-03-2018 SMALA_RS06870 2921776d026a97f2ea963913d1feb23e 1762 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1712 1727 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS06870 2921776d026a97f2ea963913d1feb23e 1762 SMART SM00825 Beta-ketoacyl synthase 37 464 4.3E-219 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS06870 2921776d026a97f2ea963913d1feb23e 1762 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 294 411 8.7E-42 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS06870 2921776d026a97f2ea963913d1feb23e 1762 SUPERFAMILY SSF53901 34 409 4.46E-98 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS06870 2921776d026a97f2ea963913d1feb23e 1762 Pfam PF08659 KR domain 1401 1579 5.7E-57 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS06870 2921776d026a97f2ea963913d1feb23e 1762 SUPERFAMILY SSF47336 1680 1755 4.06E-19 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS06870 2921776d026a97f2ea963913d1feb23e 1762 Gene3D G3DSA:3.40.366.10 753 872 5.1E-21 T 29-03-2018 SMALA_RS06870 2921776d026a97f2ea963913d1feb23e 1762 Gene3D G3DSA:3.30.70.250 709 752 4.4E-15 T 29-03-2018 SMALA_RS06870 2921776d026a97f2ea963913d1feb23e 1762 Pfam PF00550 Phosphopantetheine attachment site 1688 1747 1.3E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS06870 2921776d026a97f2ea963913d1feb23e 1762 SUPERFAMILY SSF51735 1397 1620 5.14E-43 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS06870 2921776d026a97f2ea963913d1feb23e 1762 SUPERFAMILY SSF55048 697 758 1.27E-9 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS06870 2921776d026a97f2ea963913d1feb23e 1762 Pfam PF00698 Acyl transferase domain 572 891 8.9E-80 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS06870 2921776d026a97f2ea963913d1feb23e 1762 Gene3D G3DSA:3.40.50.720 1393 1656 2.1E-48 T 29-03-2018 SMALA_RS06870 2921776d026a97f2ea963913d1feb23e 1762 Gene3D G3DSA:3.40.47.10 301 462 4.8E-61 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS06870 2921776d026a97f2ea963913d1feb23e 1762 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 414 531 1.7E-11 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS06870 2921776d026a97f2ea963913d1feb23e 1762 SUPERFAMILY SSF51735 1225 1388 9.45E-24 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS06870 2921776d026a97f2ea963913d1feb23e 1762 Gene3D G3DSA:3.40.366.10 566 708 5.3E-42 T 29-03-2018 SMALA_RS06870 2921776d026a97f2ea963913d1feb23e 1762 Gene3D G3DSA:3.40.47.10 28 298 3.5E-83 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS06870 2921776d026a97f2ea963913d1feb23e 1762 SMART SM00823 Phosphopantetheine attachment site 1685 1757 7.8E-22 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS06870 2921776d026a97f2ea963913d1feb23e 1762 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 35 286 1.6E-89 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS06870 2921776d026a97f2ea963913d1feb23e 1762 SUPERFAMILY SSF52151 763 858 3.14E-64 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS06870 2921776d026a97f2ea963913d1feb23e 1762 SUPERFAMILY SSF52151 569 699 3.14E-64 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS06870 2921776d026a97f2ea963913d1feb23e 1762 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 199 215 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS06870 2921776d026a97f2ea963913d1feb23e 1762 Pfam PF14765 Polyketide synthase dehydratase 939 1213 1.9E-56 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS14545 6c6b962f09e35fa8db338621b9b8b9c9 201 Gene3D G3DSA:3.40.50.2300 1 125 5.5E-33 T 29-03-2018 SMALA_RS14545 6c6b962f09e35fa8db338621b9b8b9c9 201 SMART SM00421 138 195 1.1E-23 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS14545 6c6b962f09e35fa8db338621b9b8b9c9 201 ProSitePatterns PS00622 LuxR-type HTH domain signature. 155 182 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS14545 6c6b962f09e35fa8db338621b9b8b9c9 201 Gene3D G3DSA:1.10.10.10 126 201 3.3E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS14545 6c6b962f09e35fa8db338621b9b8b9c9 201 SUPERFAMILY SSF46894 124 201 3.74E-20 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS14545 6c6b962f09e35fa8db338621b9b8b9c9 201 Pfam PF00072 Response regulator receiver domain 4 116 2.1E-22 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS14545 6c6b962f09e35fa8db338621b9b8b9c9 201 Pfam PF00196 Bacterial regulatory proteins, luxR family 140 195 1.3E-17 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS14545 6c6b962f09e35fa8db338621b9b8b9c9 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 171 183 3.8E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS14545 6c6b962f09e35fa8db338621b9b8b9c9 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 141 155 3.8E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS14545 6c6b962f09e35fa8db338621b9b8b9c9 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 171 3.8E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS14545 6c6b962f09e35fa8db338621b9b8b9c9 201 SMART SM00448 2 115 1.9E-23 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS14545 6c6b962f09e35fa8db338621b9b8b9c9 201 SUPERFAMILY SSF52172 1 129 1.85E-28 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS34945 17834450f0ef07224ae0c6042af40a2a 140 Gene3D G3DSA:3.10.450.50 2 128 1.5E-21 T 29-03-2018 SMALA_RS34945 17834450f0ef07224ae0c6042af40a2a 140 SUPERFAMILY SSF54427 6 126 8.33E-30 T 29-03-2018 IPR032710 NTF2-like domain SMALA_RS34945 17834450f0ef07224ae0c6042af40a2a 140 Pfam PF12680 SnoaL-like domain 13 116 5.5E-13 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain SMALA_RS26485 34b27099ba501ba93852d69aa8ac57e4 410 SUPERFAMILY SSF53223 33 181 5.25E-56 T 29-03-2018 SMALA_RS26485 34b27099ba501ba93852d69aa8ac57e4 410 Gene3D G3DSA:3.40.50.720 181 410 3.1E-68 T 29-03-2018 SMALA_RS26485 34b27099ba501ba93852d69aa8ac57e4 410 Pfam PF03949 Malic enzyme, NAD binding domain 185 384 2.5E-19 T 29-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 SMALA_RS26485 34b27099ba501ba93852d69aa8ac57e4 410 PIRSF PIRSF000106 41 410 6.9E-74 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 SMALA_RS26485 34b27099ba501ba93852d69aa8ac57e4 410 Gene3D G3DSA:3.40.50.10380 32 180 2.4E-39 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 SMALA_RS26485 34b27099ba501ba93852d69aa8ac57e4 410 SMART SM01274 38 171 5.5E-79 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 SMALA_RS26485 34b27099ba501ba93852d69aa8ac57e4 410 SMART SM00919 183 403 1.4E-105 T 29-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 SMALA_RS26485 34b27099ba501ba93852d69aa8ac57e4 410 SUPERFAMILY SSF51735 183 409 2.87E-66 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS26485 34b27099ba501ba93852d69aa8ac57e4 410 Pfam PF00390 Malic enzyme, N-terminal domain 40 171 7.2E-29 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 SMALA_RS27585 0fbb17a8308f866e34822e256f1ede7f 280 PRINTS PR00111 Alpha/beta hydrolase fold signature 55 70 1.8E-9 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS27585 0fbb17a8308f866e34822e256f1ede7f 280 PRINTS PR00111 Alpha/beta hydrolase fold signature 104 117 1.8E-9 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS27585 0fbb17a8308f866e34822e256f1ede7f 280 PRINTS PR00111 Alpha/beta hydrolase fold signature 225 239 1.8E-9 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS27585 0fbb17a8308f866e34822e256f1ede7f 280 PRINTS PR00412 Epoxide hydrolase signature 256 278 1.4E-6 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS27585 0fbb17a8308f866e34822e256f1ede7f 280 PRINTS PR00412 Epoxide hydrolase signature 104 117 1.4E-6 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS27585 0fbb17a8308f866e34822e256f1ede7f 280 PRINTS PR00412 Epoxide hydrolase signature 36 54 1.4E-6 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS27585 0fbb17a8308f866e34822e256f1ede7f 280 Pfam PF12697 Alpha/beta hydrolase family 32 272 2.6E-18 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS27585 0fbb17a8308f866e34822e256f1ede7f 280 SUPERFAMILY SSF53474 18 279 1.93E-53 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS27585 0fbb17a8308f866e34822e256f1ede7f 280 Gene3D G3DSA:3.40.50.1820 10 280 1.3E-42 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS25740 d76da818fd3f7c0ddaef616a92324612 278 Pfam PF13371 Tetratricopeptide repeat 196 278 1.6E-13 T 29-03-2018 SMALA_RS25740 d76da818fd3f7c0ddaef616a92324612 278 Pfam PF13369 Transglutaminase-like superfamily 49 194 1.2E-42 T 29-03-2018 IPR032698 Protein SirB1, N-terminal Reactome: R-HSA-8951664|Reactome: R-HSA-983168 SMALA_RS28625 e2e0c416b29181c5d668c257ed1b220d 732 Gene3D G3DSA:2.140.10.10 546 731 4.1E-15 T 29-03-2018 SMALA_RS28625 e2e0c416b29181c5d668c257ed1b220d 732 Gene3D G3DSA:2.140.10.10 297 545 2.6E-16 T 29-03-2018 SMALA_RS28625 e2e0c416b29181c5d668c257ed1b220d 732 Gene3D G3DSA:1.10.510.10 47 289 3.3E-16 T 29-03-2018 SMALA_RS28625 e2e0c416b29181c5d668c257ed1b220d 732 SMART SM00564 395 426 170.0 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMALA_RS28625 e2e0c416b29181c5d668c257ed1b220d 732 SMART SM00564 580 610 440.0 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMALA_RS28625 e2e0c416b29181c5d668c257ed1b220d 732 SMART SM00564 619 650 43.0 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMALA_RS28625 e2e0c416b29181c5d668c257ed1b220d 732 SMART SM00564 478 516 49.0 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMALA_RS28625 e2e0c416b29181c5d668c257ed1b220d 732 SMART SM00564 658 696 240.0 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMALA_RS28625 e2e0c416b29181c5d668c257ed1b220d 732 SUPERFAMILY SSF50998 379 648 2.35E-17 T 29-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily SMALA_RS28625 e2e0c416b29181c5d668c257ed1b220d 732 SMART SM00220 50 283 2.2E-4 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMALA_RS28625 e2e0c416b29181c5d668c257ed1b220d 732 Pfam PF13360 PQQ-like domain 554 712 1.6E-14 T 29-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat SMALA_RS28625 e2e0c416b29181c5d668c257ed1b220d 732 Pfam PF13360 PQQ-like domain 408 515 6.8E-9 T 29-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat SMALA_RS28625 e2e0c416b29181c5d668c257ed1b220d 732 SUPERFAMILY SSF56112 51 280 1.9E-21 T 29-03-2018 IPR011009 Protein kinase-like domain SMALA_RS19365 d0178ab37b7365040e7340e245a18715 308 SUPERFAMILY SSF52540 4 218 1.49E-53 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS19365 d0178ab37b7365040e7340e245a18715 308 SMART SM00382 27 215 8.0E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS19365 d0178ab37b7365040e7340e245a18715 308 Gene3D G3DSA:3.40.50.300 1 246 2.0E-57 T 29-03-2018 SMALA_RS19365 d0178ab37b7365040e7340e245a18715 308 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS19365 d0178ab37b7365040e7340e245a18715 308 Pfam PF00005 ABC transporter 20 159 8.1E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS22410 89dd0d72b5cc55292a7c3588124a1ea9 412 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 211 234 4.4E-11 T 29-03-2018 SMALA_RS22410 89dd0d72b5cc55292a7c3588124a1ea9 412 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 128 149 4.4E-11 T 29-03-2018 SMALA_RS22410 89dd0d72b5cc55292a7c3588124a1ea9 412 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 242 266 4.4E-11 T 29-03-2018 SMALA_RS22410 89dd0d72b5cc55292a7c3588124a1ea9 412 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 175 199 4.4E-11 T 29-03-2018 SMALA_RS22410 89dd0d72b5cc55292a7c3588124a1ea9 412 SUPERFAMILY SSF53383 16 408 1.02E-113 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS22410 89dd0d72b5cc55292a7c3588124a1ea9 412 Gene3D G3DSA:3.90.1150.10 286 411 3.9E-31 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS22410 89dd0d72b5cc55292a7c3588124a1ea9 412 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 248 261 - T 29-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 SMALA_RS22410 89dd0d72b5cc55292a7c3588124a1ea9 412 Gene3D G3DSA:3.40.640.10 66 285 1.3E-53 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS22410 89dd0d72b5cc55292a7c3588124a1ea9 412 Pfam PF00155 Aminotransferase class I and II 44 398 7.0E-74 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMALA_RS22440 23e2828b0c0ea1ee078497e68f7560b2 276 SUPERFAMILY SSF89392 150 260 4.32E-10 T 29-03-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX SMALA_RS01350 84a20e4fec8d336d2b5f8c6e38a3c673 453 Pfam PF00144 Beta-lactamase 23 333 3.0E-54 T 29-03-2018 IPR001466 Beta-lactamase-related SMALA_RS01350 84a20e4fec8d336d2b5f8c6e38a3c673 453 Gene3D G3DSA:3.40.710.10 9 346 4.2E-69 T 29-03-2018 SMALA_RS01350 84a20e4fec8d336d2b5f8c6e38a3c673 453 SUPERFAMILY SSF56601 19 341 2.11E-68 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMALA_RS09905 c5c68b55d821b601bcad1a18bfeaf946 157 SUPERFAMILY SSF50475 14 140 1.96E-30 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS09905 c5c68b55d821b601bcad1a18bfeaf946 157 Gene3D G3DSA:2.30.110.10 2 138 2.6E-27 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS09905 c5c68b55d821b601bcad1a18bfeaf946 157 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 17 141 1.1E-38 T 29-03-2018 IPR019920 F420-binding domain, putative SMALA_RS09905 c5c68b55d821b601bcad1a18bfeaf946 157 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 14 96 2.0E-14 T 29-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2770 2785 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 SMART SM00824 Thioesterase 6068 6272 0.0037 T 29-03-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1029 1044 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 SUPERFAMILY SSF56801 3262 3818 2.09E-143 T 29-03-2018 SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 SUPERFAMILY SSF52777 1116 1324 2.33E-27 T 29-03-2018 SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 SUPERFAMILY SSF52777 5169 5439 7.23E-57 T 29-03-2018 SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 Gene3D G3DSA:3.40.50.980 5592 5778 3.4E-59 T 29-03-2018 SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 SUPERFAMILY SSF47336 2101 2173 5.1E-20 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 SUPERFAMILY SSF56801 1549 2120 7.06E-150 T 29-03-2018 SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 SUPERFAMILY SSF47336 2740 2812 2.22E-20 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 Gene3D G3DSA:2.30.38.10 1909 1989 2.2E-23 T 29-03-2018 SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 SUPERFAMILY SSF47336 1000 1067 1.06E-15 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 ProSitePatterns PS00455 Putative AMP-binding domain signature. 623 634 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 SUPERFAMILY SSF52777 3893 4083 2.11E-44 T 29-03-2018 SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 Gene3D G3DSA:3.40.50.980 5442 5591 3.2E-30 T 29-03-2018 SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 ProSitePatterns PS00012 Phosphopantetheine attachment site. 6003 6018 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 SUPERFAMILY SSF52777 7 178 3.67E-47 T 29-03-2018 SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1752 1763 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 4399 4804 1.3E-126 T 29-03-2018 IPR010071 Amino acid adenylation domain SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 494 913 1.5E-138 T 29-03-2018 IPR010071 Amino acid adenylation domain SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 3322 3721 2.0E-121 T 29-03-2018 IPR010071 Amino acid adenylation domain SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1625 2023 2.4E-127 T 29-03-2018 IPR010071 Amino acid adenylation domain SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 5472 5889 1.2E-136 T 29-03-2018 IPR010071 Amino acid adenylation domain SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 Gene3D G3DSA:1.10.1220.10 4132 4157 0.023 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 Gene3D G3DSA:1.10.1220.10 2416 2439 0.088 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 SUPERFAMILY SSF52777 191 440 1.11E-55 T 29-03-2018 SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 SUPERFAMILY SSF56801 433 1018 2.62E-157 T 29-03-2018 SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 Gene3D G3DSA:1.10.1200.10 3812 3887 9.8E-23 T 29-03-2018 SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 Gene3D G3DSA:3.30.300.30 3692 3811 1.9E-38 T 29-03-2018 SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 Gene3D G3DSA:3.30.300.30 884 1008 1.3E-38 T 29-03-2018 SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 Gene3D G3DSA:3.30.300.30 4775 4894 1.7E-36 T 29-03-2018 SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 Gene3D G3DSA:3.30.300.30 1994 2110 1.7E-37 T 29-03-2018 SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 Gene3D G3DSA:3.30.300.30 5860 5985 5.2E-40 T 29-03-2018 SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 SUPERFAMILY SSF52777 4979 5156 1.01E-44 T 29-03-2018 SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 SUPERFAMILY SSF47336 3800 3870 3.93E-19 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 Gene3D G3DSA:3.40.50.980 465 628 7.2E-46 T 29-03-2018 SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 Gene3D G3DSA:3.40.50.980 3293 3448 9.7E-41 T 29-03-2018 SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 Gene3D G3DSA:3.40.50.980 4370 4529 4.6E-46 T 29-03-2018 SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 Gene3D G3DSA:3.40.50.980 1595 1757 2.4E-45 T 29-03-2018 SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 SUPERFAMILY SSF52777 2381 2626 6.11E-59 T 29-03-2018 SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 Pfam PF00668 Condensation domain 3 453 8.0E-83 T 29-03-2018 IPR001242 Condensation domain SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 Pfam PF00668 Condensation domain 2193 2640 4.7E-86 T 29-03-2018 IPR001242 Condensation domain SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 Pfam PF00668 Condensation domain 4975 5430 2.2E-76 T 29-03-2018 IPR001242 Condensation domain SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 Pfam PF00668 Condensation domain 2832 3282 2.3E-86 T 29-03-2018 IPR001242 Condensation domain SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 Pfam PF00668 Condensation domain 1118 1475 3.6E-33 T 29-03-2018 IPR001242 Condensation domain SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 Pfam PF00668 Condensation domain 3891 4356 1.4E-78 T 29-03-2018 IPR001242 Condensation domain SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 SUPERFAMILY SSF56801 4338 4904 3.66E-146 T 29-03-2018 SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 SUPERFAMILY SSF52777 2195 2367 1.22E-50 T 29-03-2018 SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 SUPERFAMILY SSF56801 5411 5992 3.66E-166 T 29-03-2018 SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 SUPERFAMILY SSF52777 4095 4365 3.0E-58 T 29-03-2018 SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 Gene3D G3DSA:2.30.38.10 801 882 3.1E-26 T 29-03-2018 SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 SUPERFAMILY SSF47336 5974 6045 2.88E-18 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3829 3844 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4915 4930 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 Pfam PF00975 Thioesterase domain 6067 6252 5.3E-23 T 29-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 SUPERFAMILY SSF52777 3020 3288 3.89E-58 T 29-03-2018 SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 Gene3D G3DSA:1.10.1200.10 4895 4960 6.1E-24 T 29-03-2018 SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 Gene3D G3DSA:1.10.1200.10 1009 1074 4.8E-19 T 29-03-2018 SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 Gene3D G3DSA:1.10.1200.10 2111 2176 6.3E-24 T 29-03-2018 SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 SUPERFAMILY SSF53474 6046 6269 3.68E-46 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 SUPERFAMILY SSF52777 1312 1574 1.22E-38 T 29-03-2018 SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 Gene3D G3DSA:3.30.559.10 1098 1317 2.3E-22 T 29-03-2018 SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 ProSitePatterns PS00455 Putative AMP-binding domain signature. 3443 3454 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 SUPERFAMILY SSF52777 2834 3006 4.67E-52 T 29-03-2018 SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 Pfam PF00501 AMP-binding enzyme 473 889 1.0E-102 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 Pfam PF00501 AMP-binding enzyme 5452 5865 1.2E-104 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 Pfam PF00501 AMP-binding enzyme 3303 3697 7.2E-85 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 Pfam PF00501 AMP-binding enzyme 1603 1999 3.7E-96 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 Pfam PF00501 AMP-binding enzyme 4378 4779 1.5E-90 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 Gene3D G3DSA:3.30.559.10 2816 3035 5.6E-50 T 29-03-2018 SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 Gene3D G3DSA:3.30.559.10 2177 2397 5.0E-49 T 29-03-2018 SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 Gene3D G3DSA:3.30.559.10 4961 5185 9.3E-42 T 29-03-2018 SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 Gene3D G3DSA:3.30.559.10 3888 4106 5.3E-44 T 29-03-2018 SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 Gene3D G3DSA:3.30.559.10 2 207 2.3E-42 T 29-03-2018 SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 Gene3D G3DSA:3.40.50.1820 6051 6277 2.3E-24 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2131 2146 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 ProSitePatterns PS00455 Putative AMP-binding domain signature. 5609 5620 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 Pfam PF00550 Phosphopantetheine attachment site 3807 3870 7.9E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 Pfam PF00550 Phosphopantetheine attachment site 2109 2172 1.7E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 Pfam PF00550 Phosphopantetheine attachment site 4893 4954 5.1E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 Pfam PF00550 Phosphopantetheine attachment site 2748 2811 1.1E-15 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 Pfam PF00550 Phosphopantetheine attachment site 1008 1067 6.7E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 Pfam PF00550 Phosphopantetheine attachment site 5981 6044 5.8E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 SMART SM00823 Phosphopantetheine attachment site 1005 1073 0.034 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 SMART SM00823 Phosphopantetheine attachment site 4891 4960 2.0E-10 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 SMART SM00823 Phosphopantetheine attachment site 2107 2176 1.8E-10 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 SMART SM00823 Phosphopantetheine attachment site 3805 3874 4.2E-9 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 SMART SM00823 Phosphopantetheine attachment site 2746 2815 6.5E-10 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 SMART SM00823 Phosphopantetheine attachment site 5979 6048 1.2E-10 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 SUPERFAMILY SSF47336 4884 4957 5.1E-20 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 Gene3D G3DSA:2.30.38.10 3607 3690 2.6E-24 T 29-03-2018 SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 Gene3D G3DSA:2.30.38.10 5779 5858 2.8E-25 T 29-03-2018 SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 Gene3D G3DSA:2.30.38.10 4690 4773 1.4E-22 T 29-03-2018 SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 Gene3D G3DSA:3.40.50.980 652 785 1.1E-29 T 29-03-2018 SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 Gene3D G3DSA:3.30.1110.20 629 651 1.7E-4 T 29-03-2018 SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 Pfam PF13193 AMP-binding enzyme C-terminal domain 4788 4865 6.2E-13 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 Pfam PF13193 AMP-binding enzyme C-terminal domain 897 979 3.2E-11 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 Pfam PF13193 AMP-binding enzyme C-terminal domain 3705 3780 1.8E-16 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 Pfam PF13193 AMP-binding enzyme C-terminal domain 5873 5952 7.7E-16 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 Pfam PF13193 AMP-binding enzyme C-terminal domain 2007 2083 4.9E-13 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 Gene3D G3DSA:1.10.1200.10 2743 2815 5.2E-24 T 29-03-2018 SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 Gene3D G3DSA:1.10.1200.10 5986 6050 9.3E-21 T 29-03-2018 SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 Gene3D G3DSA:3.40.50.980 4530 4686 1.1E-27 T 29-03-2018 SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 Gene3D G3DSA:3.40.50.980 3449 3604 3.3E-26 T 29-03-2018 SMALA_RS39210 11d6c6ef1a23631f7617972a21cc81bf 6282 Gene3D G3DSA:3.40.50.980 1758 1904 4.7E-30 T 29-03-2018 SMALA_RS06210 f7b2d1c46830400469ab0c8d320ee551 625 Gene3D G3DSA:3.30.300.30 494 603 5.7E-26 T 29-03-2018 SMALA_RS06210 f7b2d1c46830400469ab0c8d320ee551 625 ProSitePatterns PS00455 Putative AMP-binding domain signature. 236 247 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS06210 f7b2d1c46830400469ab0c8d320ee551 625 Gene3D G3DSA:3.40.50.980 242 401 6.9E-38 T 29-03-2018 SMALA_RS06210 f7b2d1c46830400469ab0c8d320ee551 625 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 4 58 2.9E-19 T 29-03-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 SMALA_RS06210 f7b2d1c46830400469ab0c8d320ee551 625 Pfam PF13193 AMP-binding enzyme C-terminal domain 510 588 4.1E-26 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS06210 f7b2d1c46830400469ab0c8d320ee551 625 Gene3D G3DSA:2.30.38.10 402 493 4.6E-17 T 29-03-2018 SMALA_RS06210 f7b2d1c46830400469ab0c8d320ee551 625 SUPERFAMILY SSF56801 4 622 4.71E-165 T 29-03-2018 SMALA_RS06210 f7b2d1c46830400469ab0c8d320ee551 625 Gene3D G3DSA:3.40.50.980 50 241 1.8E-47 T 29-03-2018 SMALA_RS06210 f7b2d1c46830400469ab0c8d320ee551 625 Pfam PF00501 AMP-binding enzyme 65 500 1.9E-88 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS41155 7cfc532794a1af76a7ce174563dbc55d 348 SUPERFAMILY SSF53807 68 343 2.2E-41 T 29-03-2018 SMALA_RS41155 7cfc532794a1af76a7ce174563dbc55d 348 Pfam PF01497 Periplasmic binding protein 73 323 2.5E-27 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 SMALA_RS41155 7cfc532794a1af76a7ce174563dbc55d 348 Gene3D G3DSA:3.40.50.1980 183 346 6.7E-34 T 29-03-2018 SMALA_RS41155 7cfc532794a1af76a7ce174563dbc55d 348 Gene3D G3DSA:3.40.50.1980 45 182 1.9E-25 T 29-03-2018 SMALA_RS26550 4777df52f53aa3a86ed34444b4c838cf 126 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 2.4E-9 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS26550 4777df52f53aa3a86ed34444b4c838cf 126 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 2.4E-9 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS26550 4777df52f53aa3a86ed34444b4c838cf 126 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 2.4E-9 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS26550 4777df52f53aa3a86ed34444b4c838cf 126 Pfam PF13411 MerR HTH family regulatory protein 1 64 3.6E-19 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS26550 4777df52f53aa3a86ed34444b4c838cf 126 Gene3D G3DSA:1.10.1660.10 54 126 2.8E-10 T 29-03-2018 SMALA_RS26550 4777df52f53aa3a86ed34444b4c838cf 126 SUPERFAMILY SSF46955 1 115 1.06E-25 T 29-03-2018 IPR009061 Putative DNA-binding domain SMALA_RS26550 4777df52f53aa3a86ed34444b4c838cf 126 SMART SM00422 1 69 1.6E-18 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS26550 4777df52f53aa3a86ed34444b4c838cf 126 Gene3D G3DSA:1.10.1660.10 1 53 8.3E-21 T 29-03-2018 SMALA_RS13770 8f118cf82dda6d9d328de4143c33a27f 3206 SMART SM00825 Beta-ketoacyl synthase 1588 2014 2.9E-223 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS13770 8f118cf82dda6d9d328de4143c33a27f 3206 SMART SM00825 Beta-ketoacyl synthase 37 463 7.6E-222 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS13770 8f118cf82dda6d9d328de4143c33a27f 3206 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1208 1387 3.3E-64 T 29-03-2018 SMALA_RS13770 8f118cf82dda6d9d328de4143c33a27f 3206 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2757 2936 7.4E-57 T 29-03-2018 SMALA_RS13770 8f118cf82dda6d9d328de4143c33a27f 3206 SUPERFAMILY SSF51735 2532 2744 1.75E-48 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS13770 8f118cf82dda6d9d328de4143c33a27f 3206 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1964 2076 2.7E-14 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13770 8f118cf82dda6d9d328de4143c33a27f 3206 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 413 533 8.3E-17 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13770 8f118cf82dda6d9d328de4143c33a27f 3206 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3075 3090 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS13770 8f118cf82dda6d9d328de4143c33a27f 3206 SUPERFAMILY SSF101173 4 35 7.85E-7 T 29-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 SMALA_RS13770 8f118cf82dda6d9d328de4143c33a27f 3206 Gene3D G3DSA:3.40.366.10 567 708 3.1E-42 T 29-03-2018 SMALA_RS13770 8f118cf82dda6d9d328de4143c33a27f 3206 Gene3D G3DSA:3.40.366.10 2114 2254 1.8E-43 T 29-03-2018 SMALA_RS13770 8f118cf82dda6d9d328de4143c33a27f 3206 Pfam PF08990 Erythronolide synthase docking 4 28 1.7E-12 T 29-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 SMALA_RS13770 8f118cf82dda6d9d328de4143c33a27f 3206 SMART SM00823 Phosphopantetheine attachment site 1493 1565 1.2E-31 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13770 8f118cf82dda6d9d328de4143c33a27f 3206 SMART SM00823 Phosphopantetheine attachment site 3048 3120 2.4E-31 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13770 8f118cf82dda6d9d328de4143c33a27f 3206 SUPERFAMILY SSF51735 981 1195 1.14E-50 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS13770 8f118cf82dda6d9d328de4143c33a27f 3206 Pfam PF00698 Acyl transferase domain 2117 2436 6.2E-87 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS13770 8f118cf82dda6d9d328de4143c33a27f 3206 Pfam PF00698 Acyl transferase domain 570 888 1.0E-87 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS13770 8f118cf82dda6d9d328de4143c33a27f 3206 Gene3D G3DSA:1.10.1200.10 1474 1574 1.1E-20 T 29-03-2018 SMALA_RS13770 8f118cf82dda6d9d328de4143c33a27f 3206 Gene3D G3DSA:1.10.1200.10 3013 3124 7.4E-18 T 29-03-2018 SMALA_RS13770 8f118cf82dda6d9d328de4143c33a27f 3206 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 198 214 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS13770 8f118cf82dda6d9d328de4143c33a27f 3206 SUPERFAMILY SSF47336 1489 1601 1.31E-24 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS13770 8f118cf82dda6d9d328de4143c33a27f 3206 Gene3D G3DSA:3.40.47.10 300 461 4.1E-61 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13770 8f118cf82dda6d9d328de4143c33a27f 3206 Gene3D G3DSA:3.40.47.10 1851 2012 9.8E-63 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13770 8f118cf82dda6d9d328de4143c33a27f 3206 Pfam PF00550 Phosphopantetheine attachment site 3051 3116 3.0E-9 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS13770 8f118cf82dda6d9d328de4143c33a27f 3206 Pfam PF00550 Phosphopantetheine attachment site 1495 1561 1.1E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS13770 8f118cf82dda6d9d328de4143c33a27f 3206 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 571 870 5.1E-118 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS13770 8f118cf82dda6d9d328de4143c33a27f 3206 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2118 2417 2.6E-120 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS13770 8f118cf82dda6d9d328de4143c33a27f 3206 Gene3D G3DSA:3.30.70.250 709 753 1.9E-18 T 29-03-2018 SMALA_RS13770 8f118cf82dda6d9d328de4143c33a27f 3206 Gene3D G3DSA:3.30.70.250 2255 2300 1.7E-19 T 29-03-2018 SMALA_RS13770 8f118cf82dda6d9d328de4143c33a27f 3206 Gene3D G3DSA:3.40.47.10 1579 1848 5.1E-85 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13770 8f118cf82dda6d9d328de4143c33a27f 3206 Gene3D G3DSA:3.40.47.10 27 297 3.3E-88 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13770 8f118cf82dda6d9d328de4143c33a27f 3206 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 293 410 8.2E-42 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS13770 8f118cf82dda6d9d328de4143c33a27f 3206 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1844 1961 1.9E-43 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS13770 8f118cf82dda6d9d328de4143c33a27f 3206 SUPERFAMILY SSF53901 31 408 2.34E-101 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13770 8f118cf82dda6d9d328de4143c33a27f 3206 SUPERFAMILY SSF55048 2242 2308 4.84E-14 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS13770 8f118cf82dda6d9d328de4143c33a27f 3206 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1520 1535 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS13770 8f118cf82dda6d9d328de4143c33a27f 3206 Gene3D G3DSA:3.40.50.720 2749 3009 2.4E-50 T 29-03-2018 SMALA_RS13770 8f118cf82dda6d9d328de4143c33a27f 3206 Gene3D G3DSA:3.40.50.720 1200 1459 2.0E-57 T 29-03-2018 SMALA_RS13770 8f118cf82dda6d9d328de4143c33a27f 3206 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1749 1765 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS13770 8f118cf82dda6d9d328de4143c33a27f 3206 SUPERFAMILY SSF53901 1582 1960 1.05E-101 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13770 8f118cf82dda6d9d328de4143c33a27f 3206 SUPERFAMILY SSF52151 762 858 2.07E-65 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS13770 8f118cf82dda6d9d328de4143c33a27f 3206 SUPERFAMILY SSF52151 567 696 2.07E-65 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS13770 8f118cf82dda6d9d328de4143c33a27f 3206 SUPERFAMILY SSF51735 2755 2995 2.27E-46 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS13770 8f118cf82dda6d9d328de4143c33a27f 3206 Pfam PF08659 KR domain 2757 2934 1.5E-59 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13770 8f118cf82dda6d9d328de4143c33a27f 3206 Pfam PF08659 KR domain 1208 1385 1.2E-61 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13770 8f118cf82dda6d9d328de4143c33a27f 3206 SMART SM01294 1494 1561 5.7E-7 T 29-03-2018 SMALA_RS13770 8f118cf82dda6d9d328de4143c33a27f 3206 SMART SM01294 3049 3116 1.7E-5 T 29-03-2018 SMALA_RS13770 8f118cf82dda6d9d328de4143c33a27f 3206 SUPERFAMILY SSF51735 1208 1433 2.43E-53 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS13770 8f118cf82dda6d9d328de4143c33a27f 3206 SUPERFAMILY SSF55048 695 761 7.98E-13 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS13770 8f118cf82dda6d9d328de4143c33a27f 3206 Gene3D G3DSA:3.40.366.10 2301 2423 9.4E-25 T 29-03-2018 SMALA_RS13770 8f118cf82dda6d9d328de4143c33a27f 3206 Gene3D G3DSA:3.40.366.10 754 876 6.5E-25 T 29-03-2018 SMALA_RS13770 8f118cf82dda6d9d328de4143c33a27f 3206 SUPERFAMILY SSF52151 2115 2243 3.92E-65 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS13770 8f118cf82dda6d9d328de4143c33a27f 3206 SUPERFAMILY SSF52151 2309 2405 3.92E-65 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS13770 8f118cf82dda6d9d328de4143c33a27f 3206 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 35 285 1.2E-91 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS13770 8f118cf82dda6d9d328de4143c33a27f 3206 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1586 1836 5.1E-93 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS13770 8f118cf82dda6d9d328de4143c33a27f 3206 SUPERFAMILY SSF47336 3046 3129 1.7E-20 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS12495 ef683cfda4cd0c2362e6981fa4120389 811 Gene3D G3DSA:2.60.40.10 672 791 1.7E-27 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS12495 ef683cfda4cd0c2362e6981fa4120389 811 SUPERFAMILY SSF52279 523 674 1.83E-45 T 29-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 SMALA_RS12495 ef683cfda4cd0c2362e6981fa4120389 811 SUPERFAMILY SSF52279 415 494 1.83E-45 T 29-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 SMALA_RS12495 ef683cfda4cd0c2362e6981fa4120389 811 PRINTS PR00133 Glycosyl hydrolase family 3 signature 124 143 3.4E-18 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SMALA_RS12495 ef683cfda4cd0c2362e6981fa4120389 811 PRINTS PR00133 Glycosyl hydrolase family 3 signature 170 186 3.4E-18 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SMALA_RS12495 ef683cfda4cd0c2362e6981fa4120389 811 PRINTS PR00133 Glycosyl hydrolase family 3 signature 201 217 3.4E-18 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SMALA_RS12495 ef683cfda4cd0c2362e6981fa4120389 811 PRINTS PR00133 Glycosyl hydrolase family 3 signature 101 117 3.4E-18 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SMALA_RS12495 ef683cfda4cd0c2362e6981fa4120389 811 PRINTS PR00133 Glycosyl hydrolase family 3 signature 272 290 3.4E-18 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SMALA_RS12495 ef683cfda4cd0c2362e6981fa4120389 811 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 415 671 4.5E-45 T 29-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 SMALA_RS12495 ef683cfda4cd0c2362e6981fa4120389 811 SUPERFAMILY SSF51445 3 414 7.05E-92 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS12495 ef683cfda4cd0c2362e6981fa4120389 811 Gene3D G3DSA:3.20.20.300 10 370 7.5E-99 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SMALA_RS12495 ef683cfda4cd0c2362e6981fa4120389 811 Gene3D G3DSA:3.40.50.1700 402 671 8.4E-65 T 29-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 SMALA_RS12495 ef683cfda4cd0c2362e6981fa4120389 811 SMART SM01217 708 778 4.7E-23 T 29-03-2018 IPR026891 Fibronectin type III-like domain SMALA_RS12495 ef683cfda4cd0c2362e6981fa4120389 811 Pfam PF14310 Fibronectin type III-like domain 708 778 6.1E-15 T 29-03-2018 IPR026891 Fibronectin type III-like domain SMALA_RS12495 ef683cfda4cd0c2362e6981fa4120389 811 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 24 352 2.6E-66 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SMALA_RS23975 3dd08fbbe2335c486c12334063f72e90 237 Gene3D G3DSA:3.40.50.2300 2 127 1.2E-15 T 29-03-2018 SMALA_RS23975 3dd08fbbe2335c486c12334063f72e90 237 Pfam PF00196 Bacterial regulatory proteins, luxR family 155 210 1.2E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS23975 3dd08fbbe2335c486c12334063f72e90 237 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 170 3.6E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS23975 3dd08fbbe2335c486c12334063f72e90 237 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 186 3.6E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS23975 3dd08fbbe2335c486c12334063f72e90 237 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 186 198 3.6E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS23975 3dd08fbbe2335c486c12334063f72e90 237 SUPERFAMILY SSF46894 142 217 6.8E-18 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS23975 3dd08fbbe2335c486c12334063f72e90 237 Gene3D G3DSA:1.10.10.10 128 220 5.1E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS23975 3dd08fbbe2335c486c12334063f72e90 237 SMART SM00421 153 210 3.2E-18 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS23975 3dd08fbbe2335c486c12334063f72e90 237 SUPERFAMILY SSF52172 2 123 2.13E-12 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS23975 3dd08fbbe2335c486c12334063f72e90 237 Pfam PF00072 Response regulator receiver domain 6 104 4.2E-7 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS38565 cb1672fd98bf3aaab1b11518b57e5c71 332 Pfam PF13404 AsnC-type helix-turn-helix domain 8 44 1.4E-8 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMALA_RS38565 cb1672fd98bf3aaab1b11518b57e5c71 332 Pfam PF01037 Lrp/AsnC ligand binding domain 243 311 1.8E-8 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain SMALA_RS38565 cb1672fd98bf3aaab1b11518b57e5c71 332 Gene3D G3DSA:1.10.10.10 179 227 5.0E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS38565 cb1672fd98bf3aaab1b11518b57e5c71 332 SUPERFAMILY SSF46785 184 227 1.28E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS38565 cb1672fd98bf3aaab1b11518b57e5c71 332 Gene3D G3DSA:3.30.70.920 59 145 0.018 T 29-03-2018 SMALA_RS38565 cb1672fd98bf3aaab1b11518b57e5c71 332 Gene3D G3DSA:3.30.70.920 229 321 3.7E-13 T 29-03-2018 SMALA_RS38565 cb1672fd98bf3aaab1b11518b57e5c71 332 Gene3D G3DSA:1.10.10.10 3 50 5.9E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS38565 cb1672fd98bf3aaab1b11518b57e5c71 332 SMART SM00344 181 282 2.9E-8 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 SMALA_RS38565 cb1672fd98bf3aaab1b11518b57e5c71 332 SUPERFAMILY SSF54909 239 318 2.15E-8 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel SMALA_RS38565 cb1672fd98bf3aaab1b11518b57e5c71 332 Pfam PF13412 Winged helix-turn-helix DNA-binding 185 223 4.0E-6 T 29-03-2018 SMALA_RS31950 eefa407844928c1c0cddd5b5a3c9e583 747 SUPERFAMILY SSF52096 6 314 1.03E-58 T 29-03-2018 IPR029045 ClpP/crotonase-like domain SMALA_RS31950 eefa407844928c1c0cddd5b5a3c9e583 747 SUPERFAMILY SSF51735 322 504 8.1E-57 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS31950 eefa407844928c1c0cddd5b5a3c9e583 747 Gene3D G3DSA:1.10.1040.10 656 746 1.5E-14 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMALA_RS31950 eefa407844928c1c0cddd5b5a3c9e583 747 Gene3D G3DSA:1.10.1040.10 505 611 9.5E-15 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMALA_RS31950 eefa407844928c1c0cddd5b5a3c9e583 747 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 325 503 1.7E-62 T 29-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 SMALA_RS31950 eefa407844928c1c0cddd5b5a3c9e583 747 Gene3D G3DSA:3.40.50.720 263 504 1.3E-66 T 29-03-2018 SMALA_RS31950 eefa407844928c1c0cddd5b5a3c9e583 747 SUPERFAMILY SSF48179 506 617 1.36E-14 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMALA_RS31950 eefa407844928c1c0cddd5b5a3c9e583 747 SUPERFAMILY SSF48179 651 667 1.36E-14 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMALA_RS31950 eefa407844928c1c0cddd5b5a3c9e583 747 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 507 606 1.4E-16 T 29-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 SMALA_RS31950 eefa407844928c1c0cddd5b5a3c9e583 747 Pfam PF00378 Enoyl-CoA hydratase/isomerase 16 209 9.5E-29 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 SMALA_RS31950 eefa407844928c1c0cddd5b5a3c9e583 747 Gene3D G3DSA:3.90.226.10 4 212 2.2E-47 T 29-03-2018 SMALA_RS31950 eefa407844928c1c0cddd5b5a3c9e583 747 SUPERFAMILY SSF48179 655 745 8.33E-16 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMALA_RS21150 1314637b6eb71b1ec22960fc3bf45f1b 397 TIGRFAM TIGR00675 dcm: DNA (cytosine-5-)-methyltransferase 12 388 8.7E-46 T 29-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 SMALA_RS21150 1314637b6eb71b1ec22960fc3bf45f1b 397 ProSitePatterns PS00094 C-5 cytosine-specific DNA methylases active site. 87 99 - T 29-03-2018 IPR018117 DNA methylase, C-5 cytosine-specific, active site KEGG: 00270+2.1.1.37|Reactome: R-HSA-212300|Reactome: R-HSA-5334118 SMALA_RS21150 1314637b6eb71b1ec22960fc3bf45f1b 397 SUPERFAMILY SSF53335 10 231 9.23E-76 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS21150 1314637b6eb71b1ec22960fc3bf45f1b 397 SUPERFAMILY SSF53335 266 395 9.23E-76 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS21150 1314637b6eb71b1ec22960fc3bf45f1b 397 Gene3D G3DSA:3.40.50.150 10 183 9.3E-48 T 29-03-2018 SMALA_RS21150 1314637b6eb71b1ec22960fc3bf45f1b 397 Pfam PF00145 C-5 cytosine-specific DNA methylase 10 391 1.3E-55 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS21150 1314637b6eb71b1ec22960fc3bf45f1b 397 ProSitePatterns PS00095 C-5 cytosine-specific DNA methylases C-terminal signature. 373 391 - T 29-03-2018 IPR031303 DNA methylase, C-5 cytosine-specific, conserved site KEGG: 00270+2.1.1.37 SMALA_RS21150 1314637b6eb71b1ec22960fc3bf45f1b 397 Gene3D G3DSA:3.90.120.10 184 382 5.5E-26 T 29-03-2018 SMALA_RS21150 1314637b6eb71b1ec22960fc3bf45f1b 397 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 174 187 3.7E-16 T 29-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 SMALA_RS21150 1314637b6eb71b1ec22960fc3bf45f1b 397 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 125 139 3.7E-16 T 29-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 SMALA_RS21150 1314637b6eb71b1ec22960fc3bf45f1b 397 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 11 27 3.7E-16 T 29-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 SMALA_RS06690 8e840a037c8726e95baed5d428e2d3d1 169 Gene3D G3DSA:1.20.1200.10 6 153 6.2E-23 T 29-03-2018 SMALA_RS06690 8e840a037c8726e95baed5d428e2d3d1 169 SUPERFAMILY SSF89028 8 147 1.41E-21 T 29-03-2018 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 SMALA_RS06690 8e840a037c8726e95baed5d428e2d3d1 169 Pfam PF01923 Cobalamin adenosyltransferase 7 143 2.0E-20 T 29-03-2018 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 SMALA_RS42400 cc1b3688f2fd1ad405333561e4d88870 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 55 6.0E-16 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS42400 cc1b3688f2fd1ad405333561e4d88870 192 SUPERFAMILY SSF46689 6 82 2.36E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS42400 cc1b3688f2fd1ad405333561e4d88870 192 ProSitePatterns PS01081 TetR-type HTH domain signature. 24 55 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site SMALA_RS42400 cc1b3688f2fd1ad405333561e4d88870 192 Gene3D G3DSA:1.10.10.60 9 52 1.7E-16 T 29-03-2018 SMALA_RS42400 cc1b3688f2fd1ad405333561e4d88870 192 Gene3D G3DSA:1.10.357.10 53 189 4.1E-18 T 29-03-2018 SMALA_RS42400 cc1b3688f2fd1ad405333561e4d88870 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 9.0E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS42400 cc1b3688f2fd1ad405333561e4d88870 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 9.0E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS36210 cea2e3035d27e8525fe607875a45db21 631 Gene3D G3DSA:3.40.710.10 427 610 2.2E-28 T 29-03-2018 SMALA_RS36210 cea2e3035d27e8525fe607875a45db21 631 Pfam PF00905 Penicillin binding protein transpeptidase domain 455 557 3.2E-11 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 SMALA_RS36210 cea2e3035d27e8525fe607875a45db21 631 Gene3D G3DSA:3.40.710.10 291 426 4.6E-27 T 29-03-2018 SMALA_RS36210 cea2e3035d27e8525fe607875a45db21 631 Pfam PF00912 Transglycosylase 94 271 9.9E-57 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 SMALA_RS36210 cea2e3035d27e8525fe607875a45db21 631 SUPERFAMILY SSF56601 304 609 1.57E-47 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMALA_RS36210 cea2e3035d27e8525fe607875a45db21 631 SUPERFAMILY SSF56601 259 275 1.57E-47 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMALA_RS36210 cea2e3035d27e8525fe607875a45db21 631 Gene3D G3DSA:1.10.3810.10 87 286 6.3E-64 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 SMALA_RS36210 cea2e3035d27e8525fe607875a45db21 631 SUPERFAMILY SSF53955 86 286 9.56E-62 T 29-03-2018 IPR023346 Lysozyme-like domain SMALA_RS06875 e6fb36ab1fa9fae8d029ddd231d4b199 1818 SUPERFAMILY SSF55048 695 760 2.09E-13 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS06875 e6fb36ab1fa9fae8d029ddd231d4b199 1818 Gene3D G3DSA:3.40.50.720 1372 1634 2.2E-42 T 29-03-2018 SMALA_RS06875 e6fb36ab1fa9fae8d029ddd231d4b199 1818 Gene3D G3DSA:3.40.47.10 23 292 7.6E-85 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS06875 e6fb36ab1fa9fae8d029ddd231d4b199 1818 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 193 209 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS06875 e6fb36ab1fa9fae8d029ddd231d4b199 1818 Pfam PF00550 Phosphopantetheine attachment site 1665 1731 2.7E-9 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS06875 e6fb36ab1fa9fae8d029ddd231d4b199 1818 SUPERFAMILY SSF51735 1378 1597 2.43E-39 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS06875 e6fb36ab1fa9fae8d029ddd231d4b199 1818 Pfam PF00698 Acyl transferase domain 569 889 2.3E-84 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS06875 e6fb36ab1fa9fae8d029ddd231d4b199 1818 Pfam PF14765 Polyketide synthase dehydratase 937 1196 1.9E-23 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS06875 e6fb36ab1fa9fae8d029ddd231d4b199 1818 Gene3D G3DSA:1.10.1200.10 1636 1742 2.4E-17 T 29-03-2018 SMALA_RS06875 e6fb36ab1fa9fae8d029ddd231d4b199 1818 SUPERFAMILY SSF51735 1204 1364 5.06E-24 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS06875 e6fb36ab1fa9fae8d029ddd231d4b199 1818 SUPERFAMILY SSF53901 27 402 7.94E-103 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS06875 e6fb36ab1fa9fae8d029ddd231d4b199 1818 Gene3D G3DSA:3.40.366.10 564 710 3.0E-41 T 29-03-2018 SMALA_RS06875 e6fb36ab1fa9fae8d029ddd231d4b199 1818 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1380 1560 1.0E-50 T 29-03-2018 SMALA_RS06875 e6fb36ab1fa9fae8d029ddd231d4b199 1818 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 288 405 3.0E-43 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS06875 e6fb36ab1fa9fae8d029ddd231d4b199 1818 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 31 280 5.0E-89 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS06875 e6fb36ab1fa9fae8d029ddd231d4b199 1818 Gene3D G3DSA:3.40.47.10 295 456 2.3E-61 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS06875 e6fb36ab1fa9fae8d029ddd231d4b199 1818 Pfam PF08659 KR domain 1380 1558 2.0E-50 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS06875 e6fb36ab1fa9fae8d029ddd231d4b199 1818 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 571 870 8.6E-113 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS06875 e6fb36ab1fa9fae8d029ddd231d4b199 1818 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 408 517 6.0E-11 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS06875 e6fb36ab1fa9fae8d029ddd231d4b199 1818 SUPERFAMILY SSF52151 567 696 9.94E-64 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS06875 e6fb36ab1fa9fae8d029ddd231d4b199 1818 SUPERFAMILY SSF52151 761 859 9.94E-64 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS06875 e6fb36ab1fa9fae8d029ddd231d4b199 1818 SMART SM00823 Phosphopantetheine attachment site 1663 1735 5.8E-26 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS06875 e6fb36ab1fa9fae8d029ddd231d4b199 1818 Gene3D G3DSA:3.40.366.10 753 874 1.0E-23 T 29-03-2018 SMALA_RS06875 e6fb36ab1fa9fae8d029ddd231d4b199 1818 SMART SM00825 Beta-ketoacyl synthase 33 458 3.8E-217 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS06875 e6fb36ab1fa9fae8d029ddd231d4b199 1818 SUPERFAMILY SSF47336 1654 1741 4.84E-19 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS06875 e6fb36ab1fa9fae8d029ddd231d4b199 1818 Gene3D G3DSA:3.30.70.250 711 752 9.4E-19 T 29-03-2018 SMALA_RS06875 e6fb36ab1fa9fae8d029ddd231d4b199 1818 SMART SM00826 937 1084 5.7E-44 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS06875 e6fb36ab1fa9fae8d029ddd231d4b199 1818 SMART SM01294 1664 1731 0.0066 T 29-03-2018 SMALA_RS00745 87a9a6d9a2f08b65b92b46bd10324702 923 Pfam PF00486 Transcriptional regulatory protein, C terminal 26 89 9.4E-11 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS00745 87a9a6d9a2f08b65b92b46bd10324702 923 SMART SM01043 103 248 5.2E-54 T 29-03-2018 IPR005158 Bacterial transcriptional activator domain SMALA_RS00745 87a9a6d9a2f08b65b92b46bd10324702 923 SUPERFAMILY SSF48452 98 265 2.85E-39 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS00745 87a9a6d9a2f08b65b92b46bd10324702 923 SMART SM00028 782 815 130.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS00745 87a9a6d9a2f08b65b92b46bd10324702 923 SMART SM00028 862 895 54.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS00745 87a9a6d9a2f08b65b92b46bd10324702 923 SMART SM00028 822 855 0.0056 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS00745 87a9a6d9a2f08b65b92b46bd10324702 923 SMART SM00028 742 775 35.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS00745 87a9a6d9a2f08b65b92b46bd10324702 923 SUPERFAMILY SSF52540 279 510 3.68E-24 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS00745 87a9a6d9a2f08b65b92b46bd10324702 923 Pfam PF03704 Bacterial transcriptional activator domain 103 248 1.3E-48 T 29-03-2018 IPR005158 Bacterial transcriptional activator domain SMALA_RS00745 87a9a6d9a2f08b65b92b46bd10324702 923 Pfam PF13424 Tetratricopeptide repeat 784 853 4.5E-11 T 29-03-2018 SMALA_RS00745 87a9a6d9a2f08b65b92b46bd10324702 923 PRINTS PR00364 Disease resistance protein signature 317 332 2.3E-10 T 29-03-2018 SMALA_RS00745 87a9a6d9a2f08b65b92b46bd10324702 923 PRINTS PR00364 Disease resistance protein signature 481 495 2.3E-10 T 29-03-2018 SMALA_RS00745 87a9a6d9a2f08b65b92b46bd10324702 923 PRINTS PR00364 Disease resistance protein signature 396 410 2.3E-10 T 29-03-2018 SMALA_RS00745 87a9a6d9a2f08b65b92b46bd10324702 923 SMART SM00862 14 96 1.7E-11 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS00745 87a9a6d9a2f08b65b92b46bd10324702 923 Gene3D G3DSA:3.40.50.300 274 444 2.5E-15 T 29-03-2018 SMALA_RS00745 87a9a6d9a2f08b65b92b46bd10324702 923 SUPERFAMILY SSF46894 2 84 1.16E-11 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS00745 87a9a6d9a2f08b65b92b46bd10324702 923 Gene3D G3DSA:3.30.70.100 792 817 5.4E-4 T 29-03-2018 SMALA_RS00745 87a9a6d9a2f08b65b92b46bd10324702 923 Gene3D G3DSA:3.30.70.100 867 901 0.1 T 29-03-2018 SMALA_RS00745 87a9a6d9a2f08b65b92b46bd10324702 923 Pfam PF00931 NB-ARC domain 317 498 9.1E-13 T 29-03-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207 SMALA_RS00745 87a9a6d9a2f08b65b92b46bd10324702 923 SUPERFAMILY SSF48452 730 897 1.01E-22 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS00745 87a9a6d9a2f08b65b92b46bd10324702 923 Gene3D G3DSA:1.10.10.10 6 104 1.7E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS00745 87a9a6d9a2f08b65b92b46bd10324702 923 Gene3D G3DSA:1.25.40.10 105 273 7.1E-27 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS00745 87a9a6d9a2f08b65b92b46bd10324702 923 Gene3D G3DSA:1.10.150.200 818 866 1.2E-9 T 29-03-2018 SMALA_RS00745 87a9a6d9a2f08b65b92b46bd10324702 923 Gene3D G3DSA:1.10.150.200 687 791 2.2E-9 T 29-03-2018 SMALA_RS05310 25c83b6e261c23634d75fdb07a451ed4 218 Pfam PF06283 Trehalose utilisation 7 216 2.4E-44 T 29-03-2018 IPR029010 ThuA-like domain SMALA_RS05310 25c83b6e261c23634d75fdb07a451ed4 218 SUPERFAMILY SSF52317 7 218 7.55E-40 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS05310 25c83b6e261c23634d75fdb07a451ed4 218 Gene3D G3DSA:3.40.50.880 6 218 2.0E-34 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS00215 ed9cabfddfea63a762dd700f91322684 436 Gene3D G3DSA:3.40.50.10840 4 240 2.5E-74 T 29-03-2018 IPR010737 Putative sugar-binding, N-terminal domain SMALA_RS00215 ed9cabfddfea63a762dd700f91322684 436 Pfam PF07005 Putative sugar-binding N-terminal domain 5 230 1.3E-68 T 29-03-2018 IPR010737 Putative sugar-binding, N-terminal domain SMALA_RS00215 ed9cabfddfea63a762dd700f91322684 436 Pfam PF17042 Putative nucleotide-binding of sugar-metabolising enzyme 255 422 1.5E-40 T 29-03-2018 IPR031475 Putative nucleotide-binding C-terminal domain SMALA_RS00215 ed9cabfddfea63a762dd700f91322684 436 SUPERFAMILY SSF142764 5 425 4.45E-123 T 29-03-2018 SMALA_RS14775 3d1520572a847a009d7c1499ab63d3c5 398 Gene3D G3DSA:1.20.1250.20 194 396 1.6E-13 T 29-03-2018 SMALA_RS14775 3d1520572a847a009d7c1499ab63d3c5 398 SUPERFAMILY SSF103473 3 393 2.09E-35 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS14775 3d1520572a847a009d7c1499ab63d3c5 398 Pfam PF07690 Major Facilitator Superfamily 3 291 8.9E-21 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS14775 3d1520572a847a009d7c1499ab63d3c5 398 Gene3D G3DSA:1.20.1250.20 1 193 6.2E-22 T 29-03-2018 SMALA_RS05265 414df2e036205ba2f259bdb291ba7b5b 382 Gene3D G3DSA:3.30.420.40 195 375 6.2E-30 T 29-03-2018 SMALA_RS05265 414df2e036205ba2f259bdb291ba7b5b 382 Gene3D G3DSA:3.30.420.40 67 194 4.3E-29 T 29-03-2018 SMALA_RS05265 414df2e036205ba2f259bdb291ba7b5b 382 Pfam PF00480 ROK family 84 369 2.7E-33 T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 SMALA_RS05265 414df2e036205ba2f259bdb291ba7b5b 382 Pfam PF12802 MarR family 7 52 1.3E-6 T 29-03-2018 SMALA_RS05265 414df2e036205ba2f259bdb291ba7b5b 382 SUPERFAMILY SSF46785 3 64 9.91E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS05265 414df2e036205ba2f259bdb291ba7b5b 382 SUPERFAMILY SSF53067 74 371 1.94E-44 T 29-03-2018 SMALA_RS05265 414df2e036205ba2f259bdb291ba7b5b 382 Gene3D G3DSA:1.10.10.10 7 66 2.0E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS36305 f0115243dacba8f0eb90b156740ba018 346 SUPERFAMILY SSF53822 90 345 1.67E-60 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SMALA_RS36305 f0115243dacba8f0eb90b156740ba018 346 Gene3D G3DSA:1.10.10.60 4 21 6.1E-4 T 29-03-2018 SMALA_RS36305 f0115243dacba8f0eb90b156740ba018 346 SMART SM00354 5 75 3.6E-22 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS36305 f0115243dacba8f0eb90b156740ba018 346 Pfam PF00356 Bacterial regulatory proteins, lacI family 7 52 2.8E-14 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS36305 f0115243dacba8f0eb90b156740ba018 346 Gene3D G3DSA:3.40.50.2300 185 346 3.9E-54 T 29-03-2018 SMALA_RS36305 f0115243dacba8f0eb90b156740ba018 346 Pfam PF13377 Periplasmic binding protein-like domain 187 345 6.8E-38 T 29-03-2018 SMALA_RS36305 f0115243dacba8f0eb90b156740ba018 346 Gene3D G3DSA:1.10.260.40 22 61 1.2E-19 T 29-03-2018 SMALA_RS36305 f0115243dacba8f0eb90b156740ba018 346 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 7 17 1.4E-6 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS36305 f0115243dacba8f0eb90b156740ba018 346 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 17 27 1.4E-6 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS36305 f0115243dacba8f0eb90b156740ba018 346 SUPERFAMILY SSF47413 5 63 1.46E-15 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS36305 f0115243dacba8f0eb90b156740ba018 346 ProSitePatterns PS00356 LacI-type HTH domain signature. 8 26 - T 29-03-2018 SMALA_RS36305 f0115243dacba8f0eb90b156740ba018 346 Gene3D G3DSA:3.40.50.2300 62 184 3.0E-26 T 29-03-2018 SMALA_RS05455 8e2b5bdcf00e5c77164799ac6c7e35ce 302 Gene3D G3DSA:1.10.10.60 136 241 1.5E-15 T 29-03-2018 SMALA_RS05455 8e2b5bdcf00e5c77164799ac6c7e35ce 302 Gene3D G3DSA:1.10.10.60 242 296 4.3E-11 T 29-03-2018 SMALA_RS05455 8e2b5bdcf00e5c77164799ac6c7e35ce 302 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 240 282 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 SMALA_RS05455 8e2b5bdcf00e5c77164799ac6c7e35ce 302 SUPERFAMILY SSF46689 188 237 8.98E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS05455 8e2b5bdcf00e5c77164799ac6c7e35ce 302 Pfam PF12833 Helix-turn-helix domain 209 284 1.3E-18 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS05455 8e2b5bdcf00e5c77164799ac6c7e35ce 302 SUPERFAMILY SSF46689 239 288 1.3E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS05455 8e2b5bdcf00e5c77164799ac6c7e35ce 302 Pfam PF06719 AraC-type transcriptional regulator N-terminus 21 174 1.7E-44 T 29-03-2018 IPR009594 Transcription regulator HTH, AraC, N-terminal SMALA_RS05455 8e2b5bdcf00e5c77164799ac6c7e35ce 302 SMART SM00342 203 286 1.8E-25 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS17505 b8512af95ff5d56003efcab40218a397 68 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 29-03-2018 IPR019844 Cold-shock conserved site SMALA_RS17505 b8512af95ff5d56003efcab40218a397 68 SMART SM00357 3 66 6.2E-31 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 SMALA_RS17505 b8512af95ff5d56003efcab40218a397 68 PRINTS PR00050 Cold shock protein signature 24 33 1.2E-19 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMALA_RS17505 b8512af95ff5d56003efcab40218a397 68 PRINTS PR00050 Cold shock protein signature 39 57 1.2E-19 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMALA_RS17505 b8512af95ff5d56003efcab40218a397 68 PRINTS PR00050 Cold shock protein signature 4 19 1.2E-19 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMALA_RS17505 b8512af95ff5d56003efcab40218a397 68 PIRSF PIRSF002599 1 67 7.1E-26 T 29-03-2018 IPR012156 Cold shock, CspA GO:0003676 SMALA_RS17505 b8512af95ff5d56003efcab40218a397 68 SUPERFAMILY SSF50249 1 64 9.31E-25 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMALA_RS17505 b8512af95ff5d56003efcab40218a397 68 Pfam PF00313 'Cold-shock' DNA-binding domain 3 64 5.8E-31 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMALA_RS17505 b8512af95ff5d56003efcab40218a397 68 Gene3D G3DSA:2.40.50.140 1 66 1.3E-28 T 29-03-2018 SMALA_RS24650 cb7910755ada4cae13717325259dd0fb 420 Pfam PF02040 Arsenical pump membrane protein 10 405 2.8E-20 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 SMALA_RS24650 cb7910755ada4cae13717325259dd0fb 420 PRINTS PR00758 Arsenical pump membrane protein signature 352 377 2.4E-12 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 SMALA_RS24650 cb7910755ada4cae13717325259dd0fb 420 PRINTS PR00758 Arsenical pump membrane protein signature 107 131 2.4E-12 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 SMALA_RS36550 92b7c599384491a9245992f0d672cbe1 2142 Gene3D G3DSA:3.10.129.10 944 1047 3.3E-10 T 29-03-2018 SMALA_RS36550 92b7c599384491a9245992f0d672cbe1 2142 SUPERFAMILY SSF47336 2048 2131 1.57E-16 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS36550 92b7c599384491a9245992f0d672cbe1 2142 SMART SM00829 1446 1759 3.2E-162 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS36550 92b7c599384491a9245992f0d672cbe1 2142 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 407 512 3.4E-12 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS36550 92b7c599384491a9245992f0d672cbe1 2142 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2081 2096 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS36550 92b7c599384491a9245992f0d672cbe1 2142 Gene3D G3DSA:3.30.70.250 701 748 1.3E-10 T 29-03-2018 SMALA_RS36550 92b7c599384491a9245992f0d672cbe1 2142 Pfam PF14765 Polyketide synthase dehydratase 937 1200 1.1E-52 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS36550 92b7c599384491a9245992f0d672cbe1 2142 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 194 210 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS36550 92b7c599384491a9245992f0d672cbe1 2142 Pfam PF00550 Phosphopantetheine attachment site 2057 2120 9.9E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS36550 92b7c599384491a9245992f0d672cbe1 2142 Pfam PF00107 Zinc-binding dehydrogenase 1588 1683 1.1E-22 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMALA_RS36550 92b7c599384491a9245992f0d672cbe1 2142 Gene3D G3DSA:1.10.1200.10 2024 2127 1.9E-17 T 29-03-2018 SMALA_RS36550 92b7c599384491a9245992f0d672cbe1 2142 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 86 281 2.8E-71 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS36550 92b7c599384491a9245992f0d672cbe1 2142 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 14 53 8.8E-7 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS36550 92b7c599384491a9245992f0d672cbe1 2142 Gene3D G3DSA:3.40.47.10 8 293 4.0E-81 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS36550 92b7c599384491a9245992f0d672cbe1 2142 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 1463 1524 8.7E-6 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS36550 92b7c599384491a9245992f0d672cbe1 2142 SMART SM00825 Beta-ketoacyl synthase 15 456 6.3E-188 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS36550 92b7c599384491a9245992f0d672cbe1 2142 Gene3D G3DSA:3.90.180.10 1686 1762 7.7E-6 T 29-03-2018 SMALA_RS36550 92b7c599384491a9245992f0d672cbe1 2142 SMART SM00826 925 1090 4.0E-30 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS36550 92b7c599384491a9245992f0d672cbe1 2142 SMART SM00823 Phosphopantetheine attachment site 2055 2126 4.0E-16 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS36550 92b7c599384491a9245992f0d672cbe1 2142 Gene3D G3DSA:3.40.366.10 749 867 2.2E-22 T 29-03-2018 SMALA_RS36550 92b7c599384491a9245992f0d672cbe1 2142 Gene3D G3DSA:3.40.50.10090 1233 1398 0.02 T 29-03-2018 SMALA_RS36550 92b7c599384491a9245992f0d672cbe1 2142 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 289 403 2.2E-38 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS36550 92b7c599384491a9245992f0d672cbe1 2142 Gene3D G3DSA:3.40.50.720 1574 1685 3.1E-27 T 29-03-2018 SMALA_RS36550 92b7c599384491a9245992f0d672cbe1 2142 SUPERFAMILY SSF52151 566 691 3.4E-61 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS36550 92b7c599384491a9245992f0d672cbe1 2142 SUPERFAMILY SSF52151 757 849 3.4E-61 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS36550 92b7c599384491a9245992f0d672cbe1 2142 Gene3D G3DSA:3.40.47.10 296 454 1.9E-57 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS36550 92b7c599384491a9245992f0d672cbe1 2142 Gene3D G3DSA:3.40.50.720 1776 2004 3.4E-44 T 29-03-2018 SMALA_RS36550 92b7c599384491a9245992f0d672cbe1 2142 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1782 1962 1.5E-48 T 29-03-2018 SMALA_RS36550 92b7c599384491a9245992f0d672cbe1 2142 SUPERFAMILY SSF51735 1548 1710 5.37E-44 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS36550 92b7c599384491a9245992f0d672cbe1 2142 SUPERFAMILY SSF55048 689 755 1.28E-9 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS36550 92b7c599384491a9245992f0d672cbe1 2142 Pfam PF08659 KR domain 1782 1960 5.1E-60 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS36550 92b7c599384491a9245992f0d672cbe1 2142 Gene3D G3DSA:3.90.180.10 1421 1573 1.1E-37 T 29-03-2018 SMALA_RS36550 92b7c599384491a9245992f0d672cbe1 2142 SUPERFAMILY SSF51735 1779 2017 1.97E-45 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS36550 92b7c599384491a9245992f0d672cbe1 2142 Gene3D G3DSA:3.40.366.10 562 700 5.9E-41 T 29-03-2018 SMALA_RS36550 92b7c599384491a9245992f0d672cbe1 2142 Pfam PF00698 Acyl transferase domain 567 883 8.8E-90 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS36550 92b7c599384491a9245992f0d672cbe1 2142 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 569 865 7.9E-93 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS36550 92b7c599384491a9245992f0d672cbe1 2142 SUPERFAMILY SSF50129 1441 1582 1.57E-34 T 29-03-2018 IPR011032 GroES-like SMALA_RS36550 92b7c599384491a9245992f0d672cbe1 2142 SUPERFAMILY SSF53901 11 63 5.03E-89 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS36550 92b7c599384491a9245992f0d672cbe1 2142 SUPERFAMILY SSF53901 90 399 5.03E-89 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS36550 92b7c599384491a9245992f0d672cbe1 2142 SUPERFAMILY SSF51735 1211 1416 1.73E-36 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS09135 fd643afd65d6d802e94169a9842f5145 259 SUPERFAMILY SSF52096 7 251 1.33E-61 T 29-03-2018 IPR029045 ClpP/crotonase-like domain SMALA_RS09135 fd643afd65d6d802e94169a9842f5145 259 Pfam PF00378 Enoyl-CoA hydratase/isomerase 15 246 8.4E-38 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 SMALA_RS09135 fd643afd65d6d802e94169a9842f5145 259 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 115 135 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 SMALA_RS09135 fd643afd65d6d802e94169a9842f5145 259 Gene3D G3DSA:1.10.12.10 217 258 1.4E-4 T 29-03-2018 IPR014748 Crontonase, C-terminal SMALA_RS09135 fd643afd65d6d802e94169a9842f5145 259 Gene3D G3DSA:3.90.226.10 2 215 3.6E-51 T 29-03-2018 SMALA_RS00685 ccfb03ed8a9e1d5b80f67a2b36c084c6 256 SUPERFAMILY SSF55961 104 248 6.93E-38 T 29-03-2018 SMALA_RS00685 ccfb03ed8a9e1d5b80f67a2b36c084c6 256 Gene3D G3DSA:1.10.10.10 1 89 1.2E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS00685 ccfb03ed8a9e1d5b80f67a2b36c084c6 256 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 53 68 4.7E-5 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS00685 ccfb03ed8a9e1d5b80f67a2b36c084c6 256 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 5 20 4.7E-5 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS00685 ccfb03ed8a9e1d5b80f67a2b36c084c6 256 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 38 53 4.7E-5 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS00685 ccfb03ed8a9e1d5b80f67a2b36c084c6 256 SMART SM00418 3 85 1.7E-16 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS00685 ccfb03ed8a9e1d5b80f67a2b36c084c6 256 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 121 242 8.0E-23 T 29-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 SMALA_RS00685 ccfb03ed8a9e1d5b80f67a2b36c084c6 256 SUPERFAMILY SSF46785 1 108 3.03E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS00685 ccfb03ed8a9e1d5b80f67a2b36c084c6 256 Pfam PF12840 Helix-turn-helix domain 2 62 1.8E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS00685 ccfb03ed8a9e1d5b80f67a2b36c084c6 256 Gene3D G3DSA:3.30.530.20 90 254 7.8E-31 T 29-03-2018 IPR023393 START-like domain SMALA_RS09390 d18cc076e9f545f2e71a4e7253f617a5 187 SUPERFAMILY SSF46689 9 78 8.48E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS09390 d18cc076e9f545f2e71a4e7253f617a5 187 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 56 2.5E-16 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS09390 d18cc076e9f545f2e71a4e7253f617a5 187 Gene3D G3DSA:1.10.357.10 59 183 9.2E-27 T 29-03-2018 SMALA_RS09390 d18cc076e9f545f2e71a4e7253f617a5 187 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 9.0E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS09390 d18cc076e9f545f2e71a4e7253f617a5 187 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 9.0E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS09390 d18cc076e9f545f2e71a4e7253f617a5 187 SUPERFAMILY SSF48498 77 162 3.78E-13 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS09390 d18cc076e9f545f2e71a4e7253f617a5 187 Gene3D G3DSA:1.10.10.60 6 58 9.5E-16 T 29-03-2018 SMALA_RS08255 3a611b9cb59f9ac1148a9f6873dca021 427 Gene3D G3DSA:1.20.1250.20 8 204 6.1E-16 T 29-03-2018 SMALA_RS08255 3a611b9cb59f9ac1148a9f6873dca021 427 Pfam PF07690 Major Facilitator Superfamily 15 312 1.1E-23 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS08255 3a611b9cb59f9ac1148a9f6873dca021 427 SUPERFAMILY SSF103473 10 398 4.32E-46 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS08255 3a611b9cb59f9ac1148a9f6873dca021 427 Gene3D G3DSA:1.20.1250.20 205 406 1.6E-21 T 29-03-2018 SMALA_RS08255 3a611b9cb59f9ac1148a9f6873dca021 427 PRINTS PR01035 Tetracycline resistance protein signature 248 268 9.0E-6 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 SMALA_RS08255 3a611b9cb59f9ac1148a9f6873dca021 427 PRINTS PR01035 Tetracycline resistance protein signature 135 157 9.0E-6 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 SMALA_RS08255 3a611b9cb59f9ac1148a9f6873dca021 427 PRINTS PR01035 Tetracycline resistance protein signature 46 65 9.0E-6 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 SMALA_RS26920 d34754a15b7a53cbfbff5065b57bafce 481 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 15 89 1.5E-23 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SMALA_RS26920 d34754a15b7a53cbfbff5065b57bafce 481 Gene3D G3DSA:3.40.50.300 92 365 2.2E-87 T 29-03-2018 SMALA_RS26920 d34754a15b7a53cbfbff5065b57bafce 481 SMART SM00382 159 345 0.0016 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS26920 d34754a15b7a53cbfbff5065b57bafce 481 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 12 478 1.0E-233 T 29-03-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 SMALA_RS26920 d34754a15b7a53cbfbff5065b57bafce 481 Hamap MF_01347 ATP synthase subunit beta [atpB]. 10 478 53.951 T 29-03-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 SMALA_RS26920 d34754a15b7a53cbfbff5065b57bafce 481 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 147 360 1.8E-63 T 29-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SMALA_RS26920 d34754a15b7a53cbfbff5065b57bafce 481 SUPERFAMILY SSF50615 12 90 1.44E-25 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SMALA_RS26920 d34754a15b7a53cbfbff5065b57bafce 481 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 351 360 - T 29-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SMALA_RS26920 d34754a15b7a53cbfbff5065b57bafce 481 SUPERFAMILY SSF52540 93 365 1.68E-85 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS26920 d34754a15b7a53cbfbff5065b57bafce 481 Gene3D G3DSA:1.10.1140.10 366 476 4.2E-36 T 29-03-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SMALA_RS26920 d34754a15b7a53cbfbff5065b57bafce 481 SUPERFAMILY SSF47917 363 478 1.73E-44 T 29-03-2018 SMALA_RS26920 d34754a15b7a53cbfbff5065b57bafce 481 Gene3D G3DSA:2.40.10.170 3 90 3.3E-29 T 29-03-2018 SMALA_RS17075 0aaa0a8f0dc8f905c2387d00f20fe012 493 Pfam PF13432 Tetratricopeptide repeat 288 354 0.01 T 29-03-2018 SMALA_RS17075 0aaa0a8f0dc8f905c2387d00f20fe012 493 SUPERFAMILY SSF48452 121 235 1.82E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS17075 0aaa0a8f0dc8f905c2387d00f20fe012 493 Pfam PF13560 Helix-turn-helix domain 12 69 1.6E-9 T 29-03-2018 SMALA_RS17075 0aaa0a8f0dc8f905c2387d00f20fe012 493 SUPERFAMILY SSF48452 213 316 8.07E-13 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS17075 0aaa0a8f0dc8f905c2387d00f20fe012 493 SUPERFAMILY SSF48452 406 473 8.07E-13 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS17075 0aaa0a8f0dc8f905c2387d00f20fe012 493 SMART SM00530 16 70 1.7E-7 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS17075 0aaa0a8f0dc8f905c2387d00f20fe012 493 Gene3D G3DSA:1.25.40.10 65 197 5.4E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS17075 0aaa0a8f0dc8f905c2387d00f20fe012 493 Gene3D G3DSA:1.25.40.10 264 478 6.8E-20 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS17075 0aaa0a8f0dc8f905c2387d00f20fe012 493 Gene3D G3DSA:1.10.260.40 27 64 9.1E-13 T 29-03-2018 SMALA_RS17075 0aaa0a8f0dc8f905c2387d00f20fe012 493 SUPERFAMILY SSF47413 11 74 2.11E-11 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS17075 0aaa0a8f0dc8f905c2387d00f20fe012 493 SMART SM00028 122 155 96.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS17075 0aaa0a8f0dc8f905c2387d00f20fe012 493 SMART SM00028 446 479 21.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS17075 0aaa0a8f0dc8f905c2387d00f20fe012 493 SMART SM00028 406 439 9.9 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS17075 0aaa0a8f0dc8f905c2387d00f20fe012 493 SMART SM00028 243 276 140.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS17075 0aaa0a8f0dc8f905c2387d00f20fe012 493 SMART SM00028 283 316 450.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS17075 0aaa0a8f0dc8f905c2387d00f20fe012 493 Gene3D G3DSA:1.10.10.60 6 26 6.6E-4 T 29-03-2018 SMALA_RS17075 0aaa0a8f0dc8f905c2387d00f20fe012 493 Gene3D G3DSA:1.25.40.10 198 263 2.4E-4 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS18405 a1abf4664df9893c320ac7fad1aeeea5 416 Gene3D G3DSA:3.30.499.10 1 147 1.8E-22 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS18405 a1abf4664df9893c320ac7fad1aeeea5 416 Gene3D G3DSA:3.30.499.10 276 415 4.0E-32 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS18405 a1abf4664df9893c320ac7fad1aeeea5 416 SUPERFAMILY SSF53732 2 412 6.67E-86 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS18405 a1abf4664df9893c320ac7fad1aeeea5 416 Gene3D G3DSA:3.40.1060.10 148 275 1.2E-19 T 29-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS18405 a1abf4664df9893c320ac7fad1aeeea5 416 Pfam PF00330 Aconitase family (aconitate hydratase) 287 408 2.0E-20 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS18405 a1abf4664df9893c320ac7fad1aeeea5 416 Pfam PF00330 Aconitase family (aconitate hydratase) 68 283 6.0E-31 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS12245 e64e34c4f360e3b8c8f6124d5703c1ae 455 Pfam PF02056 Family 4 glycosyl hydrolase 2 180 5.1E-40 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SMALA_RS12245 e64e34c4f360e3b8c8f6124d5703c1ae 455 SUPERFAMILY SSF56327 164 441 9.5E-63 T 29-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 SMALA_RS12245 e64e34c4f360e3b8c8f6124d5703c1ae 455 ProSitePatterns PS01324 Glycosyl hydrolases family 4 signature. 135 165 - T 29-03-2018 IPR019802 Glycoside hydrolase, family 4, conserved site GO:0004553|GO:0005975 SMALA_RS12245 e64e34c4f360e3b8c8f6124d5703c1ae 455 PRINTS PR00732 Glycosyl hydrolase family 4 signature 106 126 3.7E-36 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SMALA_RS12245 e64e34c4f360e3b8c8f6124d5703c1ae 455 PRINTS PR00732 Glycosyl hydrolase family 4 signature 135 152 3.7E-36 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SMALA_RS12245 e64e34c4f360e3b8c8f6124d5703c1ae 455 PRINTS PR00732 Glycosyl hydrolase family 4 signature 160 171 3.7E-36 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SMALA_RS12245 e64e34c4f360e3b8c8f6124d5703c1ae 455 PRINTS PR00732 Glycosyl hydrolase family 4 signature 92 105 3.7E-36 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SMALA_RS12245 e64e34c4f360e3b8c8f6124d5703c1ae 455 PRINTS PR00732 Glycosyl hydrolase family 4 signature 186 198 3.7E-36 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SMALA_RS12245 e64e34c4f360e3b8c8f6124d5703c1ae 455 PRINTS PR00732 Glycosyl hydrolase family 4 signature 2 17 3.7E-36 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SMALA_RS12245 e64e34c4f360e3b8c8f6124d5703c1ae 455 PRINTS PR00732 Glycosyl hydrolase family 4 signature 71 87 3.7E-36 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SMALA_RS12245 e64e34c4f360e3b8c8f6124d5703c1ae 455 SUPERFAMILY SSF51735 1 163 6.4E-46 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS12245 e64e34c4f360e3b8c8f6124d5703c1ae 455 Gene3D G3DSA:3.90.1820.10 1 449 4.9E-126 T 29-03-2018 SMALA_RS12245 e64e34c4f360e3b8c8f6124d5703c1ae 455 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 190 426 1.2E-48 T 29-03-2018 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 SMALA_RS31900 9976497c90c7a95a8ee256a8e6e89380 282 Pfam PF13560 Helix-turn-helix domain 18 68 1.2E-6 T 29-03-2018 SMALA_RS31900 9976497c90c7a95a8ee256a8e6e89380 282 Gene3D G3DSA:1.10.260.40 8 77 6.2E-9 T 29-03-2018 SMALA_RS31900 9976497c90c7a95a8ee256a8e6e89380 282 SUPERFAMILY SSF47413 16 72 2.28E-7 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS31900 9976497c90c7a95a8ee256a8e6e89380 282 SMART SM00530 21 76 0.0016 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS33335 d373736c1b85f23f6b58d1e1f6492049 630 SUPERFAMILY SSF52540 345 589 4.83E-32 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS33335 d373736c1b85f23f6b58d1e1f6492049 630 SMART SM00382 381 522 1.6E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS33335 d373736c1b85f23f6b58d1e1f6492049 630 PRINTS PR00819 CbxX/CfqX superfamily signature 344 358 1.0E-50 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 SMALA_RS33335 d373736c1b85f23f6b58d1e1f6492049 630 PRINTS PR00819 CbxX/CfqX superfamily signature 567 579 1.0E-50 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 SMALA_RS33335 d373736c1b85f23f6b58d1e1f6492049 630 PRINTS PR00819 CbxX/CfqX superfamily signature 422 436 1.0E-50 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 SMALA_RS33335 d373736c1b85f23f6b58d1e1f6492049 630 PRINTS PR00819 CbxX/CfqX superfamily signature 469 481 1.0E-50 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 SMALA_RS33335 d373736c1b85f23f6b58d1e1f6492049 630 PRINTS PR00819 CbxX/CfqX superfamily signature 384 399 1.0E-50 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 SMALA_RS33335 d373736c1b85f23f6b58d1e1f6492049 630 PRINTS PR00819 CbxX/CfqX superfamily signature 490 507 1.0E-50 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 SMALA_RS33335 d373736c1b85f23f6b58d1e1f6492049 630 PRINTS PR00819 CbxX/CfqX superfamily signature 436 455 1.0E-50 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 SMALA_RS33335 d373736c1b85f23f6b58d1e1f6492049 630 PRINTS PR00819 CbxX/CfqX superfamily signature 507 526 1.0E-50 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 SMALA_RS33335 d373736c1b85f23f6b58d1e1f6492049 630 SUPERFAMILY SSF48452 175 243 1.85E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS33335 d373736c1b85f23f6b58d1e1f6492049 630 SUPERFAMILY SSF48452 338 353 1.85E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS33335 d373736c1b85f23f6b58d1e1f6492049 630 SUPERFAMILY SSF48452 14 51 1.85E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS33335 d373736c1b85f23f6b58d1e1f6492049 630 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 386 519 1.0E-13 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 SMALA_RS33335 d373736c1b85f23f6b58d1e1f6492049 630 Gene3D G3DSA:1.25.40.10 8 57 7.2E-4 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS33335 d373736c1b85f23f6b58d1e1f6492049 630 Gene3D G3DSA:1.25.40.10 58 255 7.4E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS33335 d373736c1b85f23f6b58d1e1f6492049 630 Gene3D G3DSA:3.40.50.300 333 519 6.4E-23 T 29-03-2018 SMALA_RS22985 f8158b9042d065249f2ce236700ba0c7 423 SUPERFAMILY SSF48179 204 297 2.72E-23 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMALA_RS22985 f8158b9042d065249f2ce236700ba0c7 423 SUPERFAMILY SSF52413 309 415 1.44E-19 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 SMALA_RS22985 f8158b9042d065249f2ce236700ba0c7 423 SMART SM00984 322 416 9.7E-18 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 SMALA_RS22985 f8158b9042d065249f2ce236700ba0c7 423 SUPERFAMILY SSF51735 6 198 9.54E-34 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS22985 f8158b9042d065249f2ce236700ba0c7 423 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 204 294 1.5E-23 T 29-03-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 SMALA_RS22985 f8158b9042d065249f2ce236700ba0c7 423 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 4 412 3.5E-100 T 29-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 SMALA_RS22985 f8158b9042d065249f2ce236700ba0c7 423 Gene3D G3DSA:3.40.50.720 228 423 1.7E-47 T 29-03-2018 SMALA_RS22985 f8158b9042d065249f2ce236700ba0c7 423 Gene3D G3DSA:1.20.5.170 205 227 2.7E-10 T 29-03-2018 SMALA_RS22985 f8158b9042d065249f2ce236700ba0c7 423 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 323 414 7.5E-16 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 SMALA_RS22985 f8158b9042d065249f2ce236700ba0c7 423 PIRSF PIRSF500136 1 422 7.5E-125 T 29-03-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 SMALA_RS22985 f8158b9042d065249f2ce236700ba0c7 423 PIRSF PIRSF000124 3 421 2.9E-44 T 29-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 SMALA_RS22985 f8158b9042d065249f2ce236700ba0c7 423 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 5 186 1.0E-25 T 29-03-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 SMALA_RS22985 f8158b9042d065249f2ce236700ba0c7 423 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 5 32 - T 29-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 SMALA_RS22985 f8158b9042d065249f2ce236700ba0c7 423 Gene3D G3DSA:3.40.50.720 1 204 2.3E-35 T 29-03-2018 SMALA_RS08710 cb77fe673c57f18586d83c96dd674de9 748 Pfam PF00931 NB-ARC domain 109 291 7.9E-10 T 29-03-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207 SMALA_RS08710 cb77fe673c57f18586d83c96dd674de9 748 Gene3D G3DSA:1.25.40.10 664 738 0.0035 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS08710 cb77fe673c57f18586d83c96dd674de9 748 Gene3D G3DSA:1.25.40.10 623 663 2.5E-4 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS08710 cb77fe673c57f18586d83c96dd674de9 748 PRINTS PR00364 Disease resistance protein signature 115 130 8.5E-8 T 29-03-2018 SMALA_RS08710 cb77fe673c57f18586d83c96dd674de9 748 PRINTS PR00364 Disease resistance protein signature 276 290 8.5E-8 T 29-03-2018 SMALA_RS08710 cb77fe673c57f18586d83c96dd674de9 748 PRINTS PR00364 Disease resistance protein signature 191 205 8.5E-8 T 29-03-2018 SMALA_RS08710 cb77fe673c57f18586d83c96dd674de9 748 SUPERFAMILY SSF52540 110 337 1.94E-22 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS08710 cb77fe673c57f18586d83c96dd674de9 748 SMART SM00028 653 686 99.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS08710 cb77fe673c57f18586d83c96dd674de9 748 SMART SM00028 533 566 19.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS08710 cb77fe673c57f18586d83c96dd674de9 748 SMART SM00028 573 606 35.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS08710 cb77fe673c57f18586d83c96dd674de9 748 SMART SM00028 613 646 13.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS08710 cb77fe673c57f18586d83c96dd674de9 748 Pfam PF13424 Tetratricopeptide repeat 532 603 1.8E-10 T 29-03-2018 SMALA_RS08710 cb77fe673c57f18586d83c96dd674de9 748 Pfam PF13424 Tetratricopeptide repeat 613 675 4.8E-8 T 29-03-2018 SMALA_RS08710 cb77fe673c57f18586d83c96dd674de9 748 Gene3D G3DSA:3.40.50.300 74 229 9.4E-17 T 29-03-2018 SMALA_RS08710 cb77fe673c57f18586d83c96dd674de9 748 Gene3D G3DSA:1.10.150.200 515 582 2.5E-8 T 29-03-2018 SMALA_RS08710 cb77fe673c57f18586d83c96dd674de9 748 Gene3D G3DSA:1.10.150.200 583 622 9.5E-7 T 29-03-2018 SMALA_RS08710 cb77fe673c57f18586d83c96dd674de9 748 SUPERFAMILY SSF48452 531 699 1.57E-20 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS17030 78a34846dbcef6fa389b20be44114e0a 528 Gene3D G3DSA:3.30.300.10 416 528 2.8E-51 T 29-03-2018 SMALA_RS17030 78a34846dbcef6fa389b20be44114e0a 528 PRINTS PR00096 Glutamine amidotransferase superfamily signature 57 66 9.3E-7 T 29-03-2018 SMALA_RS17030 78a34846dbcef6fa389b20be44114e0a 528 PRINTS PR00096 Glutamine amidotransferase superfamily signature 84 95 9.3E-7 T 29-03-2018 SMALA_RS17030 78a34846dbcef6fa389b20be44114e0a 528 PRINTS PR00096 Glutamine amidotransferase superfamily signature 173 186 9.3E-7 T 29-03-2018 SMALA_RS17030 78a34846dbcef6fa389b20be44114e0a 528 SUPERFAMILY SSF54810 407 528 5.1E-47 T 29-03-2018 SMALA_RS17030 78a34846dbcef6fa389b20be44114e0a 528 Pfam PF00958 GMP synthase C terminal domain 435 527 1.9E-38 T 29-03-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 SMALA_RS17030 78a34846dbcef6fa389b20be44114e0a 528 PRINTS PR00097 Anthranilate synthase component II signature 84 95 8.0E-5 T 29-03-2018 SMALA_RS17030 78a34846dbcef6fa389b20be44114e0a 528 PRINTS PR00097 Anthranilate synthase component II signature 57 66 8.0E-5 T 29-03-2018 SMALA_RS17030 78a34846dbcef6fa389b20be44114e0a 528 PRINTS PR00097 Anthranilate synthase component II signature 173 186 8.0E-5 T 29-03-2018 SMALA_RS17030 78a34846dbcef6fa389b20be44114e0a 528 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 208 528 8.3E-147 T 29-03-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 SMALA_RS17030 78a34846dbcef6fa389b20be44114e0a 528 Gene3D G3DSA:3.40.50.620 199 415 1.6E-40 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS17030 78a34846dbcef6fa389b20be44114e0a 528 Gene3D G3DSA:3.40.50.880 10 197 3.4E-43 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS17030 78a34846dbcef6fa389b20be44114e0a 528 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 10 528 53.658 T 29-03-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 SMALA_RS17030 78a34846dbcef6fa389b20be44114e0a 528 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 84 100 1.2E-6 T 29-03-2018 SMALA_RS17030 78a34846dbcef6fa389b20be44114e0a 528 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 54 68 1.2E-6 T 29-03-2018 SMALA_RS17030 78a34846dbcef6fa389b20be44114e0a 528 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 13 27 1.2E-6 T 29-03-2018 SMALA_RS17030 78a34846dbcef6fa389b20be44114e0a 528 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 13 195 6.3E-72 T 29-03-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 SMALA_RS17030 78a34846dbcef6fa389b20be44114e0a 528 SUPERFAMILY SSF52402 189 448 4.19E-57 T 29-03-2018 SMALA_RS17030 78a34846dbcef6fa389b20be44114e0a 528 SUPERFAMILY SSF52317 13 202 7.69E-52 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS17030 78a34846dbcef6fa389b20be44114e0a 528 Pfam PF02540 NAD synthase 215 289 1.4E-7 T 29-03-2018 IPR022310 NAD/GMP synthase SMALA_RS17030 78a34846dbcef6fa389b20be44114e0a 528 Pfam PF00117 Glutamine amidotransferase class-I 15 195 4.1E-40 T 29-03-2018 IPR017926 Glutamine amidotransferase SMALA_RS27835 0cc6b0252e47d680ec5d9343ab2deb63 140 SUPERFAMILY SSF103196 4 128 1.12E-31 T 29-03-2018 SMALA_RS27835 0cc6b0252e47d680ec5d9343ab2deb63 140 SMART SM00960 12 102 9.0E-33 T 29-03-2018 IPR004942 Roadblock/LAMTOR2 domain SMALA_RS27835 0cc6b0252e47d680ec5d9343ab2deb63 140 Pfam PF03259 Roadblock/LC7 domain 12 102 5.7E-25 T 29-03-2018 IPR004942 Roadblock/LAMTOR2 domain SMALA_RS27835 0cc6b0252e47d680ec5d9343ab2deb63 140 Gene3D G3DSA:3.30.450.30 7 134 1.5E-44 T 29-03-2018 SMALA_RS36000 8804d3748d2e2233229f9b015e8402aa 304 Pfam PF00005 ABC transporter 20 159 1.1E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS36000 8804d3748d2e2233229f9b015e8402aa 304 SUPERFAMILY SSF52540 2 237 3.52E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS36000 8804d3748d2e2233229f9b015e8402aa 304 SMART SM00382 28 216 1.5E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS36000 8804d3748d2e2233229f9b015e8402aa 304 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS36000 8804d3748d2e2233229f9b015e8402aa 304 Gene3D G3DSA:3.40.50.300 1 261 2.6E-62 T 29-03-2018 SMALA_RS13160 dfc67600d3f31bec5fba90d3ba837f96 714 Pfam PF00905 Penicillin binding protein transpeptidase domain 298 657 3.9E-86 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 SMALA_RS13160 dfc67600d3f31bec5fba90d3ba837f96 714 TIGRFAM TIGR03423 pbp2_mrdA: penicillin-binding protein 2 16 661 3.8E-178 T 29-03-2018 IPR017790 Penicillin-binding protein 2 GO:0008658|GO:0016020 SMALA_RS13160 dfc67600d3f31bec5fba90d3ba837f96 714 Pfam PF03717 Penicillin-binding Protein dimerisation domain 61 246 2.1E-39 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 SMALA_RS13160 dfc67600d3f31bec5fba90d3ba837f96 714 Gene3D G3DSA:3.90.1310.10 29 257 2.6E-46 T 29-03-2018 SMALA_RS13160 dfc67600d3f31bec5fba90d3ba837f96 714 SUPERFAMILY SSF56519 52 261 8.24E-37 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 SMALA_RS13160 dfc67600d3f31bec5fba90d3ba837f96 714 SUPERFAMILY SSF56601 213 459 2.36E-84 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMALA_RS13160 dfc67600d3f31bec5fba90d3ba837f96 714 SUPERFAMILY SSF56601 516 662 2.36E-84 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMALA_RS13160 dfc67600d3f31bec5fba90d3ba837f96 714 Gene3D G3DSA:3.40.710.10 258 667 4.8E-85 T 29-03-2018 SMALA_RS41505 c34dce80bf0517e254507d0326f286b5 192 Gene3D G3DSA:1.10.10.60 51 72 1.4E-4 T 29-03-2018 SMALA_RS41505 c34dce80bf0517e254507d0326f286b5 192 Gene3D G3DSA:1.10.10.60 2 50 7.4E-15 T 29-03-2018 SMALA_RS41505 c34dce80bf0517e254507d0326f286b5 192 SUPERFAMILY SSF48498 85 189 6.92E-20 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS41505 c34dce80bf0517e254507d0326f286b5 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 64 1.1E-13 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS41505 c34dce80bf0517e254507d0326f286b5 192 Pfam PF13305 WHG domain 92 173 1.1E-14 T 29-03-2018 IPR025996 WHG domain SMALA_RS41505 c34dce80bf0517e254507d0326f286b5 192 Gene3D G3DSA:1.10.357.10 73 191 1.8E-22 T 29-03-2018 SMALA_RS41505 c34dce80bf0517e254507d0326f286b5 192 SUPERFAMILY SSF46689 7 79 4.05E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS41505 c34dce80bf0517e254507d0326f286b5 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 2.2E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS41505 c34dce80bf0517e254507d0326f286b5 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 2.2E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS23690 039dc4afc9adc76122141894964be8c4 695 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 4 144 5.4E-32 T 29-03-2018 IPR002178 PTS EIIA type-2 domain SMALA_RS23690 039dc4afc9adc76122141894964be8c4 695 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 195 284 1.4E-18 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 SMALA_RS23690 039dc4afc9adc76122141894964be8c4 695 SUPERFAMILY SSF52794 192 290 1.06E-30 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 SMALA_RS23690 039dc4afc9adc76122141894964be8c4 695 SUPERFAMILY SSF55804 2 144 1.29E-33 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 SMALA_RS23690 039dc4afc9adc76122141894964be8c4 695 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 321 660 4.7E-114 T 29-03-2018 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 SMALA_RS23690 039dc4afc9adc76122141894964be8c4 695 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 5 130 7.1E-31 T 29-03-2018 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 SMALA_RS23690 039dc4afc9adc76122141894964be8c4 695 Pfam PF02378 Phosphotransferase system, EIIC 329 605 4.0E-17 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 SMALA_RS23690 039dc4afc9adc76122141894964be8c4 695 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 194 277 4.3E-27 T 29-03-2018 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 KEGG: 00051+2.7.1.202|KEGG: 00230+2.7.1.20|MetaCyc: PWY-6619 SMALA_RS23690 039dc4afc9adc76122141894964be8c4 695 Gene3D G3DSA:3.40.930.10 1 159 1.2E-36 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 SMALA_RS23690 039dc4afc9adc76122141894964be8c4 695 Gene3D G3DSA:3.40.50.2300 192 290 3.9E-37 T 29-03-2018 SMALA_RS40600 e6594bc9ef16244ec241b8524402ee94 255 SUPERFAMILY SSF46785 10 74 6.49E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS40600 e6594bc9ef16244ec241b8524402ee94 255 SUPERFAMILY SSF48008 103 233 4.71E-19 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS40600 e6594bc9ef16244ec241b8524402ee94 255 Pfam PF07729 FCD domain 105 228 9.4E-18 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS40600 e6594bc9ef16244ec241b8524402ee94 255 SMART SM00345 19 80 1.9E-18 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS40600 e6594bc9ef16244ec241b8524402ee94 255 Gene3D G3DSA:1.10.10.10 2 76 5.0E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS40600 e6594bc9ef16244ec241b8524402ee94 255 SMART SM00895 105 232 1.0E-16 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS40600 e6594bc9ef16244ec241b8524402ee94 255 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 52 68 1.0E-11 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS40600 e6594bc9ef16244ec241b8524402ee94 255 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 38 52 1.0E-11 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS40600 e6594bc9ef16244ec241b8524402ee94 255 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 73 2.5E-22 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS40600 e6594bc9ef16244ec241b8524402ee94 255 Gene3D G3DSA:1.20.120.530 86 242 1.7E-20 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS01950 293fbf80b4b3a1ba4fc160a8057b9d10 795 Gene3D G3DSA:2.115.10.20 70 363 2.2E-63 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain SMALA_RS01950 293fbf80b4b3a1ba4fc160a8057b9d10 795 Gene3D G3DSA:2.60.120.560 385 562 3.8E-10 T 29-03-2018 SMALA_RS01950 293fbf80b4b3a1ba4fc160a8057b9d10 795 Gene3D G3DSA:2.60.120.200 583 794 7.6E-26 T 29-03-2018 SMALA_RS01950 293fbf80b4b3a1ba4fc160a8057b9d10 795 SUPERFAMILY SSF75005 54 362 2.86E-66 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain SMALA_RS01950 293fbf80b4b3a1ba4fc160a8057b9d10 795 Pfam PF04616 Glycosyl hydrolases family 43 66 360 1.5E-52 T 29-03-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 SMALA_RS01950 293fbf80b4b3a1ba4fc160a8057b9d10 795 SUPERFAMILY SSF49899 586 791 8.31E-15 T 29-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain SMALA_RS31045 3ac0a48a2abc5d866c4bfa56d4186ecc 407 SUPERFAMILY SSF53383 19 359 5.23E-37 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS31045 3ac0a48a2abc5d866c4bfa56d4186ecc 407 Pfam PF00155 Aminotransferase class I and II 38 359 4.1E-14 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMALA_RS31045 3ac0a48a2abc5d866c4bfa56d4186ecc 407 Gene3D G3DSA:3.40.640.10 20 253 1.3E-25 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS31045 3ac0a48a2abc5d866c4bfa56d4186ecc 407 Gene3D G3DSA:3.90.1150.10 254 372 2.0E-7 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS34965 1ccdac85c54993a89ae8a8aa0db508fc 374 PRINTS PR00139 Asparaginase/glutaminase family signature 304 322 3.6E-18 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 SMALA_RS34965 1ccdac85c54993a89ae8a8aa0db508fc 374 PRINTS PR00139 Asparaginase/glutaminase family signature 39 50 3.6E-18 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 SMALA_RS34965 1ccdac85c54993a89ae8a8aa0db508fc 374 PRINTS PR00139 Asparaginase/glutaminase family signature 118 136 3.6E-18 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 SMALA_RS34965 1ccdac85c54993a89ae8a8aa0db508fc 374 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 41 49 - T 29-03-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 SMALA_RS34965 1ccdac85c54993a89ae8a8aa0db508fc 374 Pfam PF00710 Asparaginase, N-terminal 38 231 1.5E-47 T 29-03-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 SMALA_RS34965 1ccdac85c54993a89ae8a8aa0db508fc 374 Gene3D G3DSA:3.40.50.1170 35 240 1.2E-47 T 29-03-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 SMALA_RS34965 1ccdac85c54993a89ae8a8aa0db508fc 374 SMART SM00870 38 359 5.0E-93 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 SMALA_RS34965 1ccdac85c54993a89ae8a8aa0db508fc 374 Gene3D G3DSA:3.40.50.40 257 365 4.7E-26 T 29-03-2018 IPR027473 L-asparaginase, C-terminal domain Reactome: R-HSA-70614 SMALA_RS34965 1ccdac85c54993a89ae8a8aa0db508fc 374 SUPERFAMILY SSF53774 34 371 1.03E-81 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 SMALA_RS34965 1ccdac85c54993a89ae8a8aa0db508fc 374 PIRSF PIRSF001220 33 369 6.0E-73 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 SMALA_RS34965 1ccdac85c54993a89ae8a8aa0db508fc 374 PIRSF PIRSF500176 35 367 3.4E-68 T 29-03-2018 SMALA_RS24505 25d3e5edfa8fe27f6332f5e3339d16bf 277 Pfam PF09339 IclR helix-turn-helix domain 4 52 1.9E-13 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMALA_RS24505 25d3e5edfa8fe27f6332f5e3339d16bf 277 SUPERFAMILY SSF55781 57 243 7.19E-48 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS24505 25d3e5edfa8fe27f6332f5e3339d16bf 277 Gene3D G3DSA:3.30.450.40 73 247 7.8E-51 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS24505 25d3e5edfa8fe27f6332f5e3339d16bf 277 Pfam PF01614 Bacterial transcriptional regulator 117 241 1.1E-28 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal SMALA_RS24505 25d3e5edfa8fe27f6332f5e3339d16bf 277 Gene3D G3DSA:1.10.10.10 1 72 1.5E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS24505 25d3e5edfa8fe27f6332f5e3339d16bf 277 SUPERFAMILY SSF46785 3 72 3.07E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS24505 25d3e5edfa8fe27f6332f5e3339d16bf 277 SMART SM00346 2 89 2.6E-24 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMALA_RS31955 d2fd90641ecde7cb4dd7937260131012 313 Pfam PF03466 LysR substrate binding domain 87 298 6.2E-31 T 29-03-2018 IPR005119 LysR, substrate-binding SMALA_RS31955 d2fd90641ecde7cb4dd7937260131012 313 SUPERFAMILY SSF46785 1 83 4.09E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS31955 d2fd90641ecde7cb4dd7937260131012 313 Gene3D G3DSA:3.40.190.10 178 269 9.4E-14 T 29-03-2018 SMALA_RS31955 d2fd90641ecde7cb4dd7937260131012 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 4.9E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS31955 d2fd90641ecde7cb4dd7937260131012 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 4.9E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS31955 d2fd90641ecde7cb4dd7937260131012 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 4.9E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS31955 d2fd90641ecde7cb4dd7937260131012 313 Gene3D G3DSA:3.40.190.10 88 177 1.4E-21 T 29-03-2018 SMALA_RS31955 d2fd90641ecde7cb4dd7937260131012 313 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 1.8E-20 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS31955 d2fd90641ecde7cb4dd7937260131012 313 Gene3D G3DSA:1.10.10.10 1 83 6.4E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS31955 d2fd90641ecde7cb4dd7937260131012 313 SUPERFAMILY SSF53850 88 300 4.83E-30 T 29-03-2018 SMALA_RS21400 c6fc495ec813b50eed20dfccc4d8a9d2 396 Pfam PF08281 Sigma-70, region 4 103 154 6.8E-11 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS21400 c6fc495ec813b50eed20dfccc4d8a9d2 396 Gene3D G3DSA:1.10.10.10 61 157 1.6E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS21400 c6fc495ec813b50eed20dfccc4d8a9d2 396 SUPERFAMILY SSF88659 94 156 2.43E-12 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS21400 c6fc495ec813b50eed20dfccc4d8a9d2 396 SUPERFAMILY SSF88946 6 84 5.89E-10 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS21400 c6fc495ec813b50eed20dfccc4d8a9d2 396 Pfam PF04542 Sigma-70 region 2 9 63 6.5E-9 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS21400 c6fc495ec813b50eed20dfccc4d8a9d2 396 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 12 156 1.3E-13 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS21400 c6fc495ec813b50eed20dfccc4d8a9d2 396 Gene3D G3DSA:1.10.1740.10 3 60 9.0E-12 T 29-03-2018 SMALA_RS05545 492bf1e523db51c25d6c5dcded5b708a 704 Gene3D G3DSA:3.30.420.150 270 548 0.0019 T 29-03-2018 SMALA_RS05545 492bf1e523db51c25d6c5dcded5b708a 704 SUPERFAMILY SSF53067 404 497 3.24E-7 T 29-03-2018 SMALA_RS05545 492bf1e523db51c25d6c5dcded5b708a 704 SUPERFAMILY SSF53067 15 88 3.24E-7 T 29-03-2018 SMALA_RS05545 492bf1e523db51c25d6c5dcded5b708a 704 SUPERFAMILY SSF53067 270 358 3.24E-7 T 29-03-2018 SMALA_RS05545 492bf1e523db51c25d6c5dcded5b708a 704 Gene3D G3DSA:3.30.420.40 6 113 1.3E-5 T 29-03-2018 SMALA_RS05545 492bf1e523db51c25d6c5dcded5b708a 704 Pfam PF01968 Hydantoinase/oxoprolinase 212 510 1.2E-91 T 29-03-2018 IPR002821 Hydantoinase/oxoprolinase GO:0016787 Reactome: R-HSA-174403 SMALA_RS05545 492bf1e523db51c25d6c5dcded5b708a 704 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 14 190 9.9E-47 T 29-03-2018 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403 SMALA_RS31695 9b42cef185f804c1afa0a43fd003115a 324 SUPERFAMILY SSF51735 113 262 2.3E-30 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS31695 9b42cef185f804c1afa0a43fd003115a 324 SUPERFAMILY SSF50129 2 138 5.63E-32 T 29-03-2018 IPR011032 GroES-like SMALA_RS31695 9b42cef185f804c1afa0a43fd003115a 324 Pfam PF13602 Zinc-binding dehydrogenase 196 321 3.2E-16 T 29-03-2018 SMALA_RS31695 9b42cef185f804c1afa0a43fd003115a 324 SMART SM00829 10 321 5.0E-12 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS31695 9b42cef185f804c1afa0a43fd003115a 324 Gene3D G3DSA:3.40.50.720 136 256 8.7E-23 T 29-03-2018 SMALA_RS31695 9b42cef185f804c1afa0a43fd003115a 324 Gene3D G3DSA:3.90.180.10 257 324 6.0E-6 T 29-03-2018 SMALA_RS31695 9b42cef185f804c1afa0a43fd003115a 324 Gene3D G3DSA:3.90.180.10 1 135 1.8E-29 T 29-03-2018 SMALA_RS04375 d99872d4fd8e41cd0c16ece671f7357e 370 TIGRFAM TIGR01686 FkbH: FkbH domain 13 323 7.3E-113 T 29-03-2018 IPR010037 FkbH domain SMALA_RS04375 d99872d4fd8e41cd0c16ece671f7357e 370 Gene3D G3DSA:3.40.50.1000 12 119 6.6E-14 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS04375 d99872d4fd8e41cd0c16ece671f7357e 370 SUPERFAMILY SSF56784 14 116 1.68E-16 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS04375 d99872d4fd8e41cd0c16ece671f7357e 370 SUPERFAMILY SSF55729 189 298 7.16E-6 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS04375 d99872d4fd8e41cd0c16ece671f7357e 370 Gene3D G3DSA:3.40.630.30 189 346 2.1E-7 T 29-03-2018 SMALA_RS04375 d99872d4fd8e41cd0c16ece671f7357e 370 TIGRFAM TIGR01681 HAD-SF-IIIC: HAD phosphatase, family IIIC 15 123 6.5E-20 T 29-03-2018 IPR010033 HAD-superfamily phosphatase, subfamily IIIC SMALA_RS35330 d06a43857dba163cfbb7e75c68d3e38f 363 SUPERFAMILY SSF46785 274 353 3.22E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS35330 d06a43857dba163cfbb7e75c68d3e38f 363 Gene3D G3DSA:1.10.10.10 252 363 1.6E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS35330 d06a43857dba163cfbb7e75c68d3e38f 363 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 330 345 5.8E-6 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS35330 d06a43857dba163cfbb7e75c68d3e38f 363 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 283 298 5.8E-6 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS35330 d06a43857dba163cfbb7e75c68d3e38f 363 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 315 330 5.8E-6 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS35330 d06a43857dba163cfbb7e75c68d3e38f 363 Pfam PF12840 Helix-turn-helix domain 284 339 1.9E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS35330 d06a43857dba163cfbb7e75c68d3e38f 363 SMART SM00419 297 344 0.0087 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 SMALA_RS35330 d06a43857dba163cfbb7e75c68d3e38f 363 SMART SM00418 281 359 2.5E-14 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS23100 db0242b8a35332144f1a5082eae9bf54 230 PIRSF PIRSF000190 16 230 5.2E-50 T 29-03-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 SMALA_RS23100 db0242b8a35332144f1a5082eae9bf54 230 Pfam PF10590 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region 187 230 1.7E-8 T 29-03-2018 IPR019576 Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 SMALA_RS23100 db0242b8a35332144f1a5082eae9bf54 230 Gene3D G3DSA:2.30.110.10 24 230 3.0E-51 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS23100 db0242b8a35332144f1a5082eae9bf54 230 SUPERFAMILY SSF50475 25 230 8.05E-45 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS23100 db0242b8a35332144f1a5082eae9bf54 230 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 56 127 1.2E-19 T 29-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 SMALA_RS41355 49c45ad4a9bcb3b76c8b1800ae62b853 213 Pfam PF01965 DJ-1/PfpI family 2 161 1.1E-21 T 29-03-2018 IPR002818 DJ-1/PfpI SMALA_RS41355 49c45ad4a9bcb3b76c8b1800ae62b853 213 Gene3D G3DSA:3.40.50.880 1 212 5.8E-48 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS41355 49c45ad4a9bcb3b76c8b1800ae62b853 213 SUPERFAMILY SSF52317 1 180 2.57E-43 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS37055 acc904bc2523c06e72742ce644347c8a 147 TIGRFAM TIGR02241 TIGR02241: conserved hypothetical phage tail region protein 10 146 6.1E-34 T 29-03-2018 IPR011747 Conserved hypothetical protein CHP02241 SMALA_RS37055 acc904bc2523c06e72742ce644347c8a 147 Pfam PF06841 T4-like virus tail tube protein gp19 12 145 1.1E-30 T 29-03-2018 IPR010667 Bacteriophage T4, Gp19, tail tube GO:0005198 SMALA_RS03205 7761cb99ea15fad13a354621d04c3c9d 226 Pfam PF03167 Uracil DNA glycosylase superfamily 55 205 1.4E-22 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SMALA_RS03205 7761cb99ea15fad13a354621d04c3c9d 226 TIGRFAM TIGR00628 ung: uracil-DNA glycosylase 7 212 4.2E-78 T 29-03-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SMALA_RS03205 7761cb99ea15fad13a354621d04c3c9d 226 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 58 67 - T 29-03-2018 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SMALA_RS03205 7761cb99ea15fad13a354621d04c3c9d 226 SMART SM00986 50 209 2.0E-32 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SMALA_RS03205 7761cb99ea15fad13a354621d04c3c9d 226 Gene3D G3DSA:3.40.470.10 2 222 2.6E-94 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SMALA_RS03205 7761cb99ea15fad13a354621d04c3c9d 226 SMART SM00987 50 209 2.0E-32 T 29-03-2018 SMALA_RS03205 7761cb99ea15fad13a354621d04c3c9d 226 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 6 220 40.223 T 29-03-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SMALA_RS03205 7761cb99ea15fad13a354621d04c3c9d 226 SUPERFAMILY SSF52141 3 220 5.42E-88 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SMALA_RS22395 a660f0fdbec720e81d59af38d2062c9f 144 SUPERFAMILY SSF54637 4 141 1.89E-28 T 29-03-2018 IPR029069 HotDog domain SMALA_RS22395 a660f0fdbec720e81d59af38d2062c9f 144 Gene3D G3DSA:3.10.129.10 2 144 1.3E-36 T 29-03-2018 SMALA_RS22395 a660f0fdbec720e81d59af38d2062c9f 144 PRINTS PR01483 Fatty acid synthase signature 25 47 4.8E-7 T 29-03-2018 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 SMALA_RS22395 a660f0fdbec720e81d59af38d2062c9f 144 PRINTS PR01483 Fatty acid synthase signature 47 68 4.8E-7 T 29-03-2018 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 SMALA_RS22395 a660f0fdbec720e81d59af38d2062c9f 144 Pfam PF01575 MaoC like domain 19 109 4.3E-24 T 29-03-2018 IPR002539 MaoC-like domain SMALA_RS28825 a04af72d3c39613bd207c1cb57fd31a4 128 SUPERFAMILY SSF52821 16 127 7.07E-20 T 29-03-2018 IPR001763 Rhodanese-like domain SMALA_RS28825 a04af72d3c39613bd207c1cb57fd31a4 128 Gene3D G3DSA:3.40.250.10 1 128 1.0E-19 T 29-03-2018 IPR001763 Rhodanese-like domain SMALA_RS28825 a04af72d3c39613bd207c1cb57fd31a4 128 SMART SM00450 21 126 6.8E-18 T 29-03-2018 IPR001763 Rhodanese-like domain SMALA_RS28825 a04af72d3c39613bd207c1cb57fd31a4 128 Pfam PF00581 Rhodanese-like domain 32 122 4.8E-10 T 29-03-2018 IPR001763 Rhodanese-like domain SMALA_RS34640 899f8a87f5cf6461b6bb33c358b696e8 248 Pfam PF07702 UTRA domain 102 232 6.1E-20 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMALA_RS34640 899f8a87f5cf6461b6bb33c358b696e8 248 SMART SM00866 94 234 5.3E-19 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMALA_RS34640 899f8a87f5cf6461b6bb33c358b696e8 248 SUPERFAMILY SSF46785 13 79 3.13E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS34640 899f8a87f5cf6461b6bb33c358b696e8 248 SUPERFAMILY SSF64288 63 237 3.93E-31 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMALA_RS34640 899f8a87f5cf6461b6bb33c358b696e8 248 Gene3D G3DSA:3.40.1410.10 82 241 4.2E-40 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMALA_RS34640 899f8a87f5cf6461b6bb33c358b696e8 248 Gene3D G3DSA:1.10.10.10 5 77 2.7E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS34640 899f8a87f5cf6461b6bb33c358b696e8 248 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 49 65 2.0E-10 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS34640 899f8a87f5cf6461b6bb33c358b696e8 248 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 35 49 2.0E-10 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS34640 899f8a87f5cf6461b6bb33c358b696e8 248 Pfam PF00392 Bacterial regulatory proteins, gntR family 25 75 5.0E-16 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS34640 899f8a87f5cf6461b6bb33c358b696e8 248 SMART SM00345 17 75 2.4E-12 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS35690 8892b5e74cfef0feb8ee0e2dfac8cc11 200 Gene3D G3DSA:1.10.357.10 58 200 1.4E-18 T 29-03-2018 SMALA_RS35690 8892b5e74cfef0feb8ee0e2dfac8cc11 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 59 7.4E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS35690 8892b5e74cfef0feb8ee0e2dfac8cc11 200 SUPERFAMILY SSF46689 10 76 1.64E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS35690 8892b5e74cfef0feb8ee0e2dfac8cc11 200 Gene3D G3DSA:1.10.10.60 1 57 1.0E-13 T 29-03-2018 SMALA_RS35690 8892b5e74cfef0feb8ee0e2dfac8cc11 200 SUPERFAMILY SSF48498 83 198 8.64E-27 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS28545 b26aa38af69ae931645a4f31b46a7ab0 409 SUPERFAMILY SSF52743 38 319 5.24E-70 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMALA_RS28545 b26aa38af69ae931645a4f31b46a7ab0 409 PRINTS PR00723 Subtilisin serine protease family (S8) signature 263 279 7.0E-13 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related SMALA_RS28545 b26aa38af69ae931645a4f31b46a7ab0 409 PRINTS PR00723 Subtilisin serine protease family (S8) signature 56 75 7.0E-13 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related SMALA_RS28545 b26aa38af69ae931645a4f31b46a7ab0 409 PRINTS PR00723 Subtilisin serine protease family (S8) signature 95 108 7.0E-13 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related SMALA_RS28545 b26aa38af69ae931645a4f31b46a7ab0 409 Pfam PF00082 Subtilase family 56 315 3.9E-46 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMALA_RS28545 b26aa38af69ae931645a4f31b46a7ab0 409 Gene3D G3DSA:3.40.50.200 23 325 7.9E-75 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMALA_RS28545 b26aa38af69ae931645a4f31b46a7ab0 409 TIGRFAM TIGR03921 T7SS_mycosin: type VII secretion-associated serine protease mycosin 45 405 2.9E-86 T 29-03-2018 IPR023834 Type VII secretion system peptidase S8A, mycosin SMALA_RS25260 b6f31ec83ff3a4c5906b7e2dcd6d8d72 463 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 2 463 55.082 T 29-03-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 SMALA_RS25260 b6f31ec83ff3a4c5906b7e2dcd6d8d72 463 Gene3D G3DSA:3.40.1060.10 153 286 2.9E-39 T 29-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS25260 b6f31ec83ff3a4c5906b7e2dcd6d8d72 463 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 4 458 4.1E-208 T 29-03-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 SMALA_RS25260 b6f31ec83ff3a4c5906b7e2dcd6d8d72 463 Pfam PF00330 Aconitase family (aconitate hydratase) 8 455 2.9E-145 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS25260 b6f31ec83ff3a4c5906b7e2dcd6d8d72 463 Gene3D G3DSA:3.30.499.10 302 463 6.8E-51 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS25260 b6f31ec83ff3a4c5906b7e2dcd6d8d72 463 ProSitePatterns PS00450 Aconitase family signature 1. 337 353 - T 29-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 SMALA_RS25260 b6f31ec83ff3a4c5906b7e2dcd6d8d72 463 Gene3D G3DSA:3.30.499.10 1 152 6.1E-36 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS25260 b6f31ec83ff3a4c5906b7e2dcd6d8d72 463 SUPERFAMILY SSF53732 3 462 7.06E-157 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS25260 b6f31ec83ff3a4c5906b7e2dcd6d8d72 463 PRINTS PR00415 Aconitase family signature 284 298 2.3E-45 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS25260 b6f31ec83ff3a4c5906b7e2dcd6d8d72 463 PRINTS PR00415 Aconitase family signature 397 410 2.3E-45 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS25260 b6f31ec83ff3a4c5906b7e2dcd6d8d72 463 PRINTS PR00415 Aconitase family signature 341 352 2.3E-45 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS25260 b6f31ec83ff3a4c5906b7e2dcd6d8d72 463 PRINTS PR00415 Aconitase family signature 131 146 2.3E-45 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS25260 b6f31ec83ff3a4c5906b7e2dcd6d8d72 463 PRINTS PR00415 Aconitase family signature 207 220 2.3E-45 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS25260 b6f31ec83ff3a4c5906b7e2dcd6d8d72 463 PRINTS PR00415 Aconitase family signature 117 130 2.3E-45 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS25260 b6f31ec83ff3a4c5906b7e2dcd6d8d72 463 PRINTS PR00415 Aconitase family signature 106 114 2.3E-45 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS25260 b6f31ec83ff3a4c5906b7e2dcd6d8d72 463 PRINTS PR00415 Aconitase family signature 193 206 2.3E-45 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS25260 b6f31ec83ff3a4c5906b7e2dcd6d8d72 463 ProSitePatterns PS01244 Aconitase family signature 2. 397 410 - T 29-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 SMALA_RS34000 866fe63d1d0acab77d84918921f69efc 384 Pfam PF09084 NMT1/THI5 like 99 254 3.8E-6 T 29-03-2018 IPR015168 SsuA/THI5-like SMALA_RS34000 866fe63d1d0acab77d84918921f69efc 384 Gene3D G3DSA:3.40.190.10 190 380 1.2E-15 T 29-03-2018 SMALA_RS34000 866fe63d1d0acab77d84918921f69efc 384 SUPERFAMILY SSF53850 97 306 1.09E-16 T 29-03-2018 SMALA_RS34000 866fe63d1d0acab77d84918921f69efc 384 Gene3D G3DSA:3.40.190.10 82 188 2.6E-8 T 29-03-2018 SMALA_RS29125 5addaa65bfc5934e60a43d0024509ea9 995 SMART SM00881 226 327 2.1E-25 T 29-03-2018 IPR003781 CoA-binding GO:0048037 SMALA_RS29125 5addaa65bfc5934e60a43d0024509ea9 995 SUPERFAMILY SSF55729 28 191 2.66E-23 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS29125 5addaa65bfc5934e60a43d0024509ea9 995 SUPERFAMILY SSF52210 358 527 1.83E-31 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMALA_RS29125 5addaa65bfc5934e60a43d0024509ea9 995 Pfam PF00583 Acetyltransferase (GNAT) family 57 184 1.3E-9 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SMALA_RS29125 5addaa65bfc5934e60a43d0024509ea9 995 Gene3D G3DSA:3.40.50.720 226 352 2.4E-43 T 29-03-2018 SMALA_RS29125 5addaa65bfc5934e60a43d0024509ea9 995 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 380 522 1.6E-36 T 29-03-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain SMALA_RS29125 5addaa65bfc5934e60a43d0024509ea9 995 Gene3D G3DSA:3.30.1490.20 792 848 1.2E-15 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SMALA_RS29125 5addaa65bfc5934e60a43d0024509ea9 995 SUPERFAMILY SSF56059 775 971 5.65E-25 T 29-03-2018 SMALA_RS29125 5addaa65bfc5934e60a43d0024509ea9 995 Gene3D G3DSA:3.40.630.30 16 225 4.6E-26 T 29-03-2018 SMALA_RS29125 5addaa65bfc5934e60a43d0024509ea9 995 SUPERFAMILY SSF52210 531 678 2.88E-15 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMALA_RS29125 5addaa65bfc5934e60a43d0024509ea9 995 Gene3D G3DSA:3.40.50.261 353 524 1.6E-38 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMALA_RS29125 5addaa65bfc5934e60a43d0024509ea9 995 Pfam PF13549 ATP-grasp domain 771 977 1.8E-54 T 29-03-2018 SMALA_RS29125 5addaa65bfc5934e60a43d0024509ea9 995 Gene3D G3DSA:3.30.470.20 849 982 9.1E-34 T 29-03-2018 SMALA_RS29125 5addaa65bfc5934e60a43d0024509ea9 995 Gene3D G3DSA:3.40.50.261 556 683 4.0E-28 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMALA_RS29125 5addaa65bfc5934e60a43d0024509ea9 995 Gene3D G3DSA:3.40.50.261 528 555 0.01 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMALA_RS29125 5addaa65bfc5934e60a43d0024509ea9 995 Pfam PF13380 CoA binding domain 231 362 2.0E-16 T 29-03-2018 IPR003781 CoA-binding GO:0048037 SMALA_RS29125 5addaa65bfc5934e60a43d0024509ea9 995 SUPERFAMILY SSF51735 224 356 1.62E-29 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS23020 b668daa06fb45c953d959996a3c287a4 387 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 123 2.5E-23 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS23020 b668daa06fb45c953d959996a3c287a4 387 SUPERFAMILY SSF56645 2 247 2.75E-72 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMALA_RS23020 b668daa06fb45c953d959996a3c287a4 387 Gene3D G3DSA:2.40.110.10 124 224 6.2E-31 T 29-03-2018 SMALA_RS23020 b668daa06fb45c953d959996a3c287a4 387 Gene3D G3DSA:1.10.540.10 1 123 5.9E-30 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS23020 b668daa06fb45c953d959996a3c287a4 387 Gene3D G3DSA:1.20.140.10 225 387 9.9E-32 T 29-03-2018 SMALA_RS23020 b668daa06fb45c953d959996a3c287a4 387 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 236 381 2.6E-28 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMALA_RS23020 b668daa06fb45c953d959996a3c287a4 387 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 127 223 9.3E-21 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 SMALA_RS23020 b668daa06fb45c953d959996a3c287a4 387 SUPERFAMILY SSF47203 236 385 1.92E-17 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMALA_RS38770 1c568b99fa8a4d7154cf61b9a349fce4 40 Gene3D G3DSA:1.10.3300.10 1 32 6.2E-11 T 29-03-2018 IPR023286 ABATE domain SMALA_RS38770 1c568b99fa8a4d7154cf61b9a349fce4 40 SUPERFAMILY SSF160904 1 29 1.7E-11 T 29-03-2018 SMALA_RS38770 1c568b99fa8a4d7154cf61b9a349fce4 40 Pfam PF11706 CGNR zinc finger 1 30 2.3E-12 T 29-03-2018 IPR021005 Zinc finger, CGNR SMALA_RS06945 0fced2268c618a02e339849bd7b9c231 794 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 475 665 2.6E-48 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS06945 0fced2268c618a02e339849bd7b9c231 794 Gene3D G3DSA:3.60.40.10 422 668 2.0E-42 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS06945 0fced2268c618a02e339849bd7b9c231 794 Gene3D G3DSA:3.30.450.40 237 421 1.7E-31 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS06945 0fced2268c618a02e339849bd7b9c231 794 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 125 241 1.8E-7 T 29-03-2018 IPR000014 PAS domain SMALA_RS06945 0fced2268c618a02e339849bd7b9c231 794 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 15 105 1.8E-8 T 29-03-2018 IPR000014 PAS domain SMALA_RS06945 0fced2268c618a02e339849bd7b9c231 794 Pfam PF13581 Histidine kinase-like ATPase domain 678 773 2.0E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS06945 0fced2268c618a02e339849bd7b9c231 794 SMART SM00091 116 185 2.6 T 29-03-2018 IPR000014 PAS domain SMALA_RS06945 0fced2268c618a02e339849bd7b9c231 794 SMART SM00091 3 69 2.4 T 29-03-2018 IPR000014 PAS domain SMALA_RS06945 0fced2268c618a02e339849bd7b9c231 794 Pfam PF08448 PAS fold 125 236 1.3E-19 T 29-03-2018 IPR013656 PAS fold-4 SMALA_RS06945 0fced2268c618a02e339849bd7b9c231 794 SMART SM00331 448 665 2.0E-33 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS06945 0fced2268c618a02e339849bd7b9c231 794 Gene3D G3DSA:3.30.450.20 115 236 8.7E-17 T 29-03-2018 SMALA_RS06945 0fced2268c618a02e339849bd7b9c231 794 Gene3D G3DSA:3.30.450.20 10 108 5.8E-13 T 29-03-2018 SMALA_RS06945 0fced2268c618a02e339849bd7b9c231 794 SUPERFAMILY SSF55785 133 241 1.48E-10 T 29-03-2018 IPR000014 PAS domain SMALA_RS06945 0fced2268c618a02e339849bd7b9c231 794 SUPERFAMILY SSF55781 356 427 2.62E-13 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS06945 0fced2268c618a02e339849bd7b9c231 794 SUPERFAMILY SSF55874 709 786 1.19E-6 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS06945 0fced2268c618a02e339849bd7b9c231 794 Pfam PF01590 GAF domain 262 417 1.6E-7 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS06945 0fced2268c618a02e339849bd7b9c231 794 SUPERFAMILY SSF55785 10 105 1.94E-12 T 29-03-2018 IPR000014 PAS domain SMALA_RS06945 0fced2268c618a02e339849bd7b9c231 794 SUPERFAMILY SSF81606 465 664 3.92E-5 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS06945 0fced2268c618a02e339849bd7b9c231 794 Pfam PF00989 PAS fold 19 104 8.3E-7 T 29-03-2018 IPR013767 PAS fold GO:0006355 SMALA_RS06945 0fced2268c618a02e339849bd7b9c231 794 Gene3D G3DSA:3.30.565.10 669 789 4.4E-11 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS40255 8b5a6cb88a76c4012892305a2b997ae3 188 SUPERFAMILY SSF46689 9 68 9.93E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS40255 8b5a6cb88a76c4012892305a2b997ae3 188 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 55 7.8E-13 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS40255 8b5a6cb88a76c4012892305a2b997ae3 188 Gene3D G3DSA:1.10.357.10 53 187 8.9E-19 T 29-03-2018 SMALA_RS40255 8b5a6cb88a76c4012892305a2b997ae3 188 Gene3D G3DSA:1.10.10.60 8 52 3.9E-15 T 29-03-2018 SMALA_RS40255 8b5a6cb88a76c4012892305a2b997ae3 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 4.0E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS40255 8b5a6cb88a76c4012892305a2b997ae3 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 4.0E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS33260 55da312c8acce2c8d47d6dacf10e64af 288 SUPERFAMILY SSF47413 29 80 6.22E-8 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS33260 55da312c8acce2c8d47d6dacf10e64af 288 Pfam PF13560 Helix-turn-helix domain 5 84 6.9E-20 T 29-03-2018 SMALA_RS33260 55da312c8acce2c8d47d6dacf10e64af 288 Gene3D G3DSA:1.10.260.40 1 86 1.8E-16 T 29-03-2018 SMALA_RS33260 55da312c8acce2c8d47d6dacf10e64af 288 SMART SM00530 9 81 2.0E-9 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS05375 64b1fcc68bad0f44b07197634289b5e4 486 Gene3D G3DSA:3.30.420.40 1 242 2.1E-50 T 29-03-2018 SMALA_RS05375 64b1fcc68bad0f44b07197634289b5e4 486 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 1 246 6.6E-41 T 29-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 SMALA_RS05375 64b1fcc68bad0f44b07197634289b5e4 486 Gene3D G3DSA:3.30.420.40 243 486 5.2E-37 T 29-03-2018 SMALA_RS05375 64b1fcc68bad0f44b07197634289b5e4 486 SUPERFAMILY SSF53067 251 475 5.4E-31 T 29-03-2018 SMALA_RS05375 64b1fcc68bad0f44b07197634289b5e4 486 PIRSF PIRSF000538 1 485 5.7E-78 T 29-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 SMALA_RS05375 64b1fcc68bad0f44b07197634289b5e4 486 SUPERFAMILY SSF53067 2 249 4.86E-47 T 29-03-2018 SMALA_RS05375 64b1fcc68bad0f44b07197634289b5e4 486 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 260 435 2.7E-17 T 29-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 SMALA_RS21900 cda2da5883bdf164d889444d9f04d1e9 462 Gene3D G3DSA:3.50.50.60 253 331 2.9E-4 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS21900 cda2da5883bdf164d889444d9f04d1e9 462 SUPERFAMILY SSF51905 15 192 5.18E-34 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS21900 cda2da5883bdf164d889444d9f04d1e9 462 Gene3D G3DSA:3.30.390.30 343 420 1.0E-16 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SMALA_RS21900 cda2da5883bdf164d889444d9f04d1e9 462 SUPERFAMILY SSF51905 154 330 1.11E-22 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS21900 cda2da5883bdf164d889444d9f04d1e9 462 Pfam PF14759 Reductase C-terminal 343 411 2.9E-9 T 29-03-2018 IPR028202 Reductase, C-terminal SMALA_RS21900 cda2da5883bdf164d889444d9f04d1e9 462 Gene3D G3DSA:3.50.50.60 111 252 7.8E-23 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS21900 cda2da5883bdf164d889444d9f04d1e9 462 SUPERFAMILY SSF55424 336 413 1.65E-18 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SMALA_RS21900 cda2da5883bdf164d889444d9f04d1e9 462 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 15 321 1.5E-40 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS21900 cda2da5883bdf164d889444d9f04d1e9 462 Gene3D G3DSA:3.50.50.60 3 110 7.0E-12 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS21900 cda2da5883bdf164d889444d9f04d1e9 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 109 127 5.9E-10 T 29-03-2018 SMALA_RS21900 cda2da5883bdf164d889444d9f04d1e9 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 16 35 5.9E-10 T 29-03-2018 SMALA_RS21900 cda2da5883bdf164d889444d9f04d1e9 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 243 259 5.9E-10 T 29-03-2018 SMALA_RS21900 cda2da5883bdf164d889444d9f04d1e9 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 156 174 5.9E-10 T 29-03-2018 SMALA_RS21900 cda2da5883bdf164d889444d9f04d1e9 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 156 181 8.2E-11 T 29-03-2018 SMALA_RS21900 cda2da5883bdf164d889444d9f04d1e9 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 244 258 8.2E-11 T 29-03-2018 SMALA_RS21900 cda2da5883bdf164d889444d9f04d1e9 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 290 297 8.2E-11 T 29-03-2018 SMALA_RS21900 cda2da5883bdf164d889444d9f04d1e9 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 15 37 8.2E-11 T 29-03-2018 SMALA_RS18785 8790e4ae91b74a919dcc927c95927c14 199 Pfam PF13662 Toprim domain 80 170 3.3E-26 T 29-03-2018 IPR006171 TOPRIM domain SMALA_RS18785 8790e4ae91b74a919dcc927c95927c14 199 TIGRFAM TIGR00615 recR: recombination protein RecR 2 195 1.8E-85 T 29-03-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 SMALA_RS18785 8790e4ae91b74a919dcc927c95927c14 199 Pfam PF02132 RecR protein 38 77 1.4E-16 T 29-03-2018 IPR023628 Recombination protein RecR, C4-type zinc finger SMALA_RS18785 8790e4ae91b74a919dcc927c95927c14 199 Pfam PF00633 Helix-hairpin-helix motif 2 27 7.4E-6 T 29-03-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 SMALA_RS18785 8790e4ae91b74a919dcc927c95927c14 199 SMART SM00493 79 164 5.2E-16 T 29-03-2018 IPR006171 TOPRIM domain SMALA_RS18785 8790e4ae91b74a919dcc927c95927c14 199 Hamap MF_00017 Recombination protein RecR [recR]. 1 197 108.888 T 29-03-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 SMALA_RS18785 8790e4ae91b74a919dcc927c95927c14 199 SUPERFAMILY SSF111304 3 197 1.96E-75 T 29-03-2018 IPR023627 Recombination protein RecR SMALA_RS18785 8790e4ae91b74a919dcc927c95927c14 199 ProSitePatterns PS01300 RecR protein signature. 56 77 - T 29-03-2018 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 SMALA_RS18785 8790e4ae91b74a919dcc927c95927c14 199 Gene3D G3DSA:3.40.1360.10 76 169 2.6E-40 T 29-03-2018 SMALA_RS28720 177603c65ef2dd6461fbba4e616492d4 875 SUPERFAMILY SSF55785 158 252 6.98E-16 T 29-03-2018 IPR000014 PAS domain SMALA_RS28720 177603c65ef2dd6461fbba4e616492d4 875 Pfam PF13492 GAF domain 562 623 4.8E-8 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS28720 177603c65ef2dd6461fbba4e616492d4 875 SMART SM00091 148 214 3.6E-4 T 29-03-2018 IPR000014 PAS domain SMALA_RS28720 177603c65ef2dd6461fbba4e616492d4 875 Pfam PF00989 PAS fold 158 258 4.6E-9 T 29-03-2018 IPR013767 PAS fold GO:0006355 SMALA_RS28720 177603c65ef2dd6461fbba4e616492d4 875 SMART SM00331 652 869 1.3E-65 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS28720 177603c65ef2dd6461fbba4e616492d4 875 Pfam PF13581 Histidine kinase-like ATPase domain 15 126 2.2E-7 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS28720 177603c65ef2dd6461fbba4e616492d4 875 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 158 257 1.8E-9 T 29-03-2018 IPR000014 PAS domain SMALA_RS28720 177603c65ef2dd6461fbba4e616492d4 875 Gene3D G3DSA:3.30.450.40 439 629 1.5E-24 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS28720 177603c65ef2dd6461fbba4e616492d4 875 Pfam PF13185 GAF domain 298 433 1.1E-10 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS28720 177603c65ef2dd6461fbba4e616492d4 875 Gene3D G3DSA:3.30.450.20 155 261 4.8E-14 T 29-03-2018 SMALA_RS28720 177603c65ef2dd6461fbba4e616492d4 875 SUPERFAMILY SSF81606 661 869 2.25E-6 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS28720 177603c65ef2dd6461fbba4e616492d4 875 SUPERFAMILY SSF55781 448 629 3.17E-12 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS28720 177603c65ef2dd6461fbba4e616492d4 875 SUPERFAMILY SSF55781 299 437 1.57E-20 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS28720 177603c65ef2dd6461fbba4e616492d4 875 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 679 869 5.9E-42 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS28720 177603c65ef2dd6461fbba4e616492d4 875 SMART SM00065 463 631 0.024 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS28720 177603c65ef2dd6461fbba4e616492d4 875 SMART SM00065 298 442 1.5E-11 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS28720 177603c65ef2dd6461fbba4e616492d4 875 Gene3D G3DSA:3.30.565.10 1 142 6.2E-12 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS28720 177603c65ef2dd6461fbba4e616492d4 875 Gene3D G3DSA:3.60.40.10 630 870 7.5E-33 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS28720 177603c65ef2dd6461fbba4e616492d4 875 Gene3D G3DSA:3.30.450.40 295 438 1.3E-20 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS32855 47fd91f7c75e9f979362d2bd67a4d9ee 659 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 66 655 32.831 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 SMALA_RS32855 47fd91f7c75e9f979362d2bd67a4d9ee 659 Gene3D G3DSA:3.30.54.20 145 192 4.4E-17 T 29-03-2018 SMALA_RS32855 47fd91f7c75e9f979362d2bd67a4d9ee 659 Gene3D G3DSA:3.30.980.10 193 239 3.4E-14 T 29-03-2018 SMALA_RS32855 47fd91f7c75e9f979362d2bd67a4d9ee 659 SUPERFAMILY SSF55681 260 547 1.57E-90 T 29-03-2018 SMALA_RS32855 47fd91f7c75e9f979362d2bd67a4d9ee 659 Gene3D G3DSA:3.30.980.10 70 144 1.3E-18 T 29-03-2018 SMALA_RS32855 47fd91f7c75e9f979362d2bd67a4d9ee 659 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 190 236 1.6E-13 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 SMALA_RS32855 47fd91f7c75e9f979362d2bd67a4d9ee 659 SUPERFAMILY SSF52954 550 654 2.27E-27 T 29-03-2018 IPR004154 Anticodon-binding SMALA_RS32855 47fd91f7c75e9f979362d2bd67a4d9ee 659 PRINTS PR01047 Threonyl-tRNA synthetase signature 381 404 1.2E-48 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 SMALA_RS32855 47fd91f7c75e9f979362d2bd67a4d9ee 659 PRINTS PR01047 Threonyl-tRNA synthetase signature 528 541 1.2E-48 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 SMALA_RS32855 47fd91f7c75e9f979362d2bd67a4d9ee 659 PRINTS PR01047 Threonyl-tRNA synthetase signature 348 376 1.2E-48 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 SMALA_RS32855 47fd91f7c75e9f979362d2bd67a4d9ee 659 PRINTS PR01047 Threonyl-tRNA synthetase signature 485 513 1.2E-48 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 SMALA_RS32855 47fd91f7c75e9f979362d2bd67a4d9ee 659 PRINTS PR01047 Threonyl-tRNA synthetase signature 555 567 1.2E-48 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 SMALA_RS32855 47fd91f7c75e9f979362d2bd67a4d9ee 659 SUPERFAMILY SSF55186 64 258 2.88E-50 T 29-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 SMALA_RS32855 47fd91f7c75e9f979362d2bd67a4d9ee 659 Gene3D G3DSA:3.30.930.10 240 552 1.0E-107 T 29-03-2018 SMALA_RS32855 47fd91f7c75e9f979362d2bd67a4d9ee 659 SMART SM00863 180 236 7.8E-20 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 SMALA_RS32855 47fd91f7c75e9f979362d2bd67a4d9ee 659 Pfam PF03129 Anticodon binding domain 562 650 2.0E-18 T 29-03-2018 IPR004154 Anticodon-binding SMALA_RS32855 47fd91f7c75e9f979362d2bd67a4d9ee 659 Gene3D G3DSA:3.40.50.800 556 658 3.2E-25 T 29-03-2018 IPR004154 Anticodon-binding SMALA_RS32855 47fd91f7c75e9f979362d2bd67a4d9ee 659 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 343 550 1.1E-36 T 29-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMALA_RS32855 47fd91f7c75e9f979362d2bd67a4d9ee 659 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 72 650 2.5E-194 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 SMALA_RS39690 a5b0c2b80a1c5ed4f0016049754faad0 266 SMART SM01134 74 235 1.4E-56 T 29-03-2018 SMALA_RS39690 a5b0c2b80a1c5ed4f0016049754faad0 266 Pfam PF08220 DeoR-like helix-turn-helix domain 8 59 5.0E-14 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMALA_RS39690 a5b0c2b80a1c5ed4f0016049754faad0 266 Gene3D G3DSA:1.10.10.10 5 70 2.5E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS39690 a5b0c2b80a1c5ed4f0016049754faad0 266 SMART SM00420 8 60 1.7E-12 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMALA_RS39690 a5b0c2b80a1c5ed4f0016049754faad0 266 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 40 58 1.1E-7 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMALA_RS39690 a5b0c2b80a1c5ed4f0016049754faad0 266 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 26 40 1.1E-7 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMALA_RS39690 a5b0c2b80a1c5ed4f0016049754faad0 266 SUPERFAMILY SSF46785 8 61 1.62E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS39690 a5b0c2b80a1c5ed4f0016049754faad0 266 Gene3D G3DSA:3.40.50.1360 71 239 3.3E-37 T 29-03-2018 SMALA_RS39690 a5b0c2b80a1c5ed4f0016049754faad0 266 Pfam PF00455 DeoR C terminal sensor domain 77 233 1.6E-41 T 29-03-2018 IPR014036 DeoR C-terminal sensor domain SMALA_RS39690 a5b0c2b80a1c5ed4f0016049754faad0 266 SUPERFAMILY SSF100950 77 236 6.61E-25 T 29-03-2018 SMALA_RS27495 3580db4c3a5f3c592bab099a5452f6e8 175 SUPERFAMILY SSF46785 10 145 4.1E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS27495 3580db4c3a5f3c592bab099a5452f6e8 175 Gene3D G3DSA:1.10.10.10 2 147 2.9E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS27495 3580db4c3a5f3c592bab099a5452f6e8 175 Pfam PF12802 MarR family 38 96 2.8E-12 T 29-03-2018 SMALA_RS27495 3580db4c3a5f3c592bab099a5452f6e8 175 PRINTS PR00598 Bacterial regulatory protein MarR family signature 57 73 1.9E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS27495 3580db4c3a5f3c592bab099a5452f6e8 175 PRINTS PR00598 Bacterial regulatory protein MarR family signature 74 89 1.9E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS27495 3580db4c3a5f3c592bab099a5452f6e8 175 PRINTS PR00598 Bacterial regulatory protein MarR family signature 93 109 1.9E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS27495 3580db4c3a5f3c592bab099a5452f6e8 175 PRINTS PR00598 Bacterial regulatory protein MarR family signature 123 143 1.9E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS27495 3580db4c3a5f3c592bab099a5452f6e8 175 SMART SM00347 33 133 1.6E-19 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS34380 fe1a09505fc6da65bdfaa42401c648a3 390 Pfam PF03144 Elongation factor Tu domain 2 224 290 1.5E-11 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 SMALA_RS34380 fe1a09505fc6da65bdfaa42401c648a3 390 SUPERFAMILY SSF50447 204 298 9.03E-26 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain SMALA_RS34380 fe1a09505fc6da65bdfaa42401c648a3 390 Gene3D G3DSA:3.40.50.300 2 73 4.1E-11 T 29-03-2018 SMALA_RS34380 fe1a09505fc6da65bdfaa42401c648a3 390 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site SMALA_RS34380 fe1a09505fc6da65bdfaa42401c648a3 390 SUPERFAMILY SSF50465 300 390 7.77E-26 T 29-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal SMALA_RS34380 fe1a09505fc6da65bdfaa42401c648a3 390 SUPERFAMILY SSF52540 8 225 2.24E-54 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS34380 fe1a09505fc6da65bdfaa42401c648a3 390 Pfam PF03143 Elongation factor Tu C-terminal domain 296 388 2.3E-21 T 29-03-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal SMALA_RS34380 fe1a09505fc6da65bdfaa42401c648a3 390 Gene3D G3DSA:2.40.30.10 297 389 3.8E-24 T 29-03-2018 SMALA_RS34380 fe1a09505fc6da65bdfaa42401c648a3 390 Gene3D G3DSA:3.40.50.300 74 191 4.0E-25 T 29-03-2018 SMALA_RS34380 fe1a09505fc6da65bdfaa42401c648a3 390 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 389 5.0E-170 T 29-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SMALA_RS34380 fe1a09505fc6da65bdfaa42401c648a3 390 PRINTS PR00315 GTP-binding elongation factor signature 58 66 2.7E-23 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMALA_RS34380 fe1a09505fc6da65bdfaa42401c648a3 390 PRINTS PR00315 GTP-binding elongation factor signature 78 88 2.7E-23 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMALA_RS34380 fe1a09505fc6da65bdfaa42401c648a3 390 PRINTS PR00315 GTP-binding elongation factor signature 14 27 2.7E-23 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMALA_RS34380 fe1a09505fc6da65bdfaa42401c648a3 390 PRINTS PR00315 GTP-binding elongation factor signature 94 105 2.7E-23 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMALA_RS34380 fe1a09505fc6da65bdfaa42401c648a3 390 PRINTS PR00315 GTP-binding elongation factor signature 131 140 2.7E-23 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMALA_RS34380 fe1a09505fc6da65bdfaa42401c648a3 390 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 390 52.595 T 29-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SMALA_RS34380 fe1a09505fc6da65bdfaa42401c648a3 390 Gene3D G3DSA:2.40.30.10 192 295 1.7E-27 T 29-03-2018 SMALA_RS34380 fe1a09505fc6da65bdfaa42401c648a3 390 Pfam PF00009 Elongation factor Tu GTP binding domain 10 200 1.7E-53 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMALA_RS34380 fe1a09505fc6da65bdfaa42401c648a3 390 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 14 147 3.5E-13 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 SMALA_RS42760 a74f63e0624d247c25d94450dba2622a 484 Gene3D G3DSA:3.90.1150.10 369 468 6.3E-19 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS42760 a74f63e0624d247c25d94450dba2622a 484 SMART SM00345 42 101 1.8E-11 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS42760 a74f63e0624d247c25d94450dba2622a 484 SUPERFAMILY SSF46785 32 111 8.59E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS42760 a74f63e0624d247c25d94450dba2622a 484 Pfam PF00155 Aminotransferase class I and II 156 460 6.2E-25 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMALA_RS42760 a74f63e0624d247c25d94450dba2622a 484 SUPERFAMILY SSF53383 109 464 1.12E-71 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS42760 a74f63e0624d247c25d94450dba2622a 484 Gene3D G3DSA:1.10.10.10 32 102 9.1E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS42760 a74f63e0624d247c25d94450dba2622a 484 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 75 91 7.2E-8 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS42760 a74f63e0624d247c25d94450dba2622a 484 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 61 75 7.2E-8 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS42760 a74f63e0624d247c25d94450dba2622a 484 Gene3D G3DSA:3.40.640.10 159 368 1.2E-35 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS42760 a74f63e0624d247c25d94450dba2622a 484 Pfam PF00392 Bacterial regulatory proteins, gntR family 42 101 7.7E-14 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS00540 a2f84f59e5ab3cc9d3056eddacdc7a0b 218 Gene3D G3DSA:1.10.10.10 121 195 8.7E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS00540 a2f84f59e5ab3cc9d3056eddacdc7a0b 218 SUPERFAMILY SSF46785 128 203 4.99E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS28355 a48bcacaa1987c60c61b80778164c3a4 265 Gene3D G3DSA:1.10.3720.10 11 265 3.5E-37 T 29-03-2018 SMALA_RS28355 a48bcacaa1987c60c61b80778164c3a4 265 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 255 3.5E-15 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS28355 a48bcacaa1987c60c61b80778164c3a4 265 SUPERFAMILY SSF161098 6 256 2.62E-48 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS23235 7e495330fef5e0d0c81a5b4375e97865 374 Gene3D G3DSA:1.10.4080.10 15 357 2.0E-85 T 29-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 SMALA_RS23235 7e495330fef5e0d0c81a5b4375e97865 374 Pfam PF03747 ADP-ribosylglycohydrolase 26 328 8.0E-70 T 29-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 SMALA_RS23235 7e495330fef5e0d0c81a5b4375e97865 374 SUPERFAMILY SSF101478 19 349 3.92E-68 T 29-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 SMALA_RS29285 2e333307954f5ac898266d5274379f13 408 SUPERFAMILY SSF48264 30 407 3.41E-87 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS29285 2e333307954f5ac898266d5274379f13 408 Pfam PF00067 Cytochrome P450 277 391 1.0E-15 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS29285 2e333307954f5ac898266d5274379f13 408 PRINTS PR00359 B-class P450 signature 91 102 1.3E-28 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS29285 2e333307954f5ac898266d5274379f13 408 PRINTS PR00359 B-class P450 signature 278 289 1.3E-28 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS29285 2e333307954f5ac898266d5274379f13 408 PRINTS PR00359 B-class P450 signature 296 323 1.3E-28 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS29285 2e333307954f5ac898266d5274379f13 408 PRINTS PR00359 B-class P450 signature 347 356 1.3E-28 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS29285 2e333307954f5ac898266d5274379f13 408 PRINTS PR00359 B-class P450 signature 356 367 1.3E-28 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS29285 2e333307954f5ac898266d5274379f13 408 PRINTS PR00359 B-class P450 signature 140 156 1.3E-28 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS29285 2e333307954f5ac898266d5274379f13 408 PRINTS PR00359 B-class P450 signature 195 217 1.3E-28 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS29285 2e333307954f5ac898266d5274379f13 408 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 349 358 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMALA_RS29285 2e333307954f5ac898266d5274379f13 408 PRINTS PR00385 P450 superfamily signature 278 289 4.6E-5 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS29285 2e333307954f5ac898266d5274379f13 408 PRINTS PR00385 P450 superfamily signature 243 260 4.6E-5 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS29285 2e333307954f5ac898266d5274379f13 408 PRINTS PR00385 P450 superfamily signature 356 367 4.6E-5 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS29285 2e333307954f5ac898266d5274379f13 408 PRINTS PR00385 P450 superfamily signature 347 356 4.6E-5 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS29285 2e333307954f5ac898266d5274379f13 408 Gene3D G3DSA:1.10.630.10 24 408 1.0E-71 T 29-03-2018 SMALA_RS28160 75d0fae85296aba676673b139bb9773b 278 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 59 246 9.9E-38 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SMALA_RS28160 75d0fae85296aba676673b139bb9773b 278 Pfam PF10502 Signal peptidase, peptidase S26 152 240 1.6E-6 T 29-03-2018 IPR019533 Peptidase S26 SMALA_RS28160 75d0fae85296aba676673b139bb9773b 278 SUPERFAMILY SSF51306 72 119 5.58E-48 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C SMALA_RS28160 75d0fae85296aba676673b139bb9773b 278 SUPERFAMILY SSF51306 147 252 5.58E-48 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C SMALA_RS28160 75d0fae85296aba676673b139bb9773b 278 Pfam PF00717 Peptidase S24-like 79 117 4.4E-10 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C SMALA_RS28160 75d0fae85296aba676673b139bb9773b 278 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 72 88 1.6E-21 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SMALA_RS28160 75d0fae85296aba676673b139bb9773b 278 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 152 164 1.6E-21 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SMALA_RS28160 75d0fae85296aba676673b139bb9773b 278 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 200 219 1.6E-21 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SMALA_RS28160 75d0fae85296aba676673b139bb9773b 278 Gene3D G3DSA:2.10.109.10 68 260 1.3E-45 T 29-03-2018 SMALA_RS28160 75d0fae85296aba676673b139bb9773b 278 ProSitePatterns PS00761 Signal peptidases I signature 3. 205 218 - T 29-03-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 SMALA_RS35605 058061e959c49460eabfe0034c4942a0 215 Pfam PF00072 Response regulator receiver domain 5 102 5.3E-16 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS35605 058061e959c49460eabfe0034c4942a0 215 Gene3D G3DSA:1.10.10.10 135 215 6.5E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS35605 058061e959c49460eabfe0034c4942a0 215 SUPERFAMILY SSF52172 3 178 4.97E-20 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS35605 058061e959c49460eabfe0034c4942a0 215 SMART SM00421 149 206 1.5E-15 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS35605 058061e959c49460eabfe0034c4942a0 215 Gene3D G3DSA:3.40.50.2300 2 134 4.1E-26 T 29-03-2018 SMALA_RS35605 058061e959c49460eabfe0034c4942a0 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 182 194 1.2E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS35605 058061e959c49460eabfe0034c4942a0 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 182 1.2E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS35605 058061e959c49460eabfe0034c4942a0 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 152 166 1.2E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS35605 058061e959c49460eabfe0034c4942a0 215 Pfam PF00196 Bacterial regulatory proteins, luxR family 151 197 2.8E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS35605 058061e959c49460eabfe0034c4942a0 215 SMART SM00448 3 123 1.1E-11 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS42375 01145fbe50c1279b7d7658f40c7d2038 219 Pfam PF08044 Domain of unknown function (DUF1707) 20 72 1.1E-18 T 29-03-2018 IPR012551 Protein of unknown function DUF1707 SMALA_RS18650 32f455506e22ef5645dc2d978eb254fd 156 SUPERFAMILY SSF55298 5 154 2.67E-56 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SMALA_RS18650 32f455506e22ef5645dc2d978eb254fd 156 Gene3D G3DSA:3.30.1330.40 3 156 1.6E-31 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SMALA_RS18650 32f455506e22ef5645dc2d978eb254fd 156 Pfam PF14588 YjgF/chorismate_mutase-like, putative endoribonuclease 7 153 5.5E-34 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SMALA_RS33000 7ff0e36502404e9a5d1f62ce9a1f76bf 300 Gene3D G3DSA:3.20.180.10 202 298 1.0E-25 T 29-03-2018 IPR019595 Domain of unknown function DUF2470 SMALA_RS33000 7ff0e36502404e9a5d1f62ce9a1f76bf 300 SUPERFAMILY SSF50475 60 298 4.71E-17 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS33000 7ff0e36502404e9a5d1f62ce9a1f76bf 300 Pfam PF10615 Protein of unknown function (DUF2470) 215 293 9.6E-6 T 29-03-2018 IPR019595 Domain of unknown function DUF2470 SMALA_RS06450 ec0257fa1046b3cf74eb91de2204cfe1 1944 Pfam PF00975 Thioesterase domain 1732 1935 2.1E-16 T 29-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 SMALA_RS06450 ec0257fa1046b3cf74eb91de2204cfe1 1944 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 553 837 6.9E-103 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS06450 ec0257fa1046b3cf74eb91de2204cfe1 1944 Gene3D G3DSA:3.40.47.10 298 458 2.0E-63 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS06450 ec0257fa1046b3cf74eb91de2204cfe1 1944 SUPERFAMILY SSF53901 31 404 9.01E-102 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS06450 ec0257fa1046b3cf74eb91de2204cfe1 1944 Gene3D G3DSA:3.40.47.10 25 295 2.7E-85 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS06450 ec0257fa1046b3cf74eb91de2204cfe1 1944 SUPERFAMILY SSF52151 550 674 4.71E-67 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS06450 ec0257fa1046b3cf74eb91de2204cfe1 1944 SUPERFAMILY SSF52151 735 831 4.71E-67 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS06450 ec0257fa1046b3cf74eb91de2204cfe1 1944 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1620 1635 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS06450 ec0257fa1046b3cf74eb91de2204cfe1 1944 SMART SM01294 1594 1661 1.7E-7 T 29-03-2018 SMALA_RS06450 ec0257fa1046b3cf74eb91de2204cfe1 1944 Pfam PF00698 Acyl transferase domain 553 844 8.7E-49 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS06450 ec0257fa1046b3cf74eb91de2204cfe1 1944 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 196 212 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS06450 ec0257fa1046b3cf74eb91de2204cfe1 1944 SUPERFAMILY SSF51735 1178 1310 2.36E-18 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS06450 ec0257fa1046b3cf74eb91de2204cfe1 1944 Gene3D G3DSA:3.40.50.720 1322 1562 4.9E-47 T 29-03-2018 SMALA_RS06450 ec0257fa1046b3cf74eb91de2204cfe1 1944 SMART SM00826 903 1059 9.6E-70 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS06450 ec0257fa1046b3cf74eb91de2204cfe1 1944 SUPERFAMILY SSF51735 1322 1570 1.09E-43 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS06450 ec0257fa1046b3cf74eb91de2204cfe1 1944 Pfam PF00550 Phosphopantetheine attachment site 1595 1661 6.5E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS06450 ec0257fa1046b3cf74eb91de2204cfe1 1944 SUPERFAMILY SSF53474 1623 1661 7.02E-35 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS06450 ec0257fa1046b3cf74eb91de2204cfe1 1944 SUPERFAMILY SSF53474 1708 1942 7.02E-35 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS06450 ec0257fa1046b3cf74eb91de2204cfe1 1944 Gene3D G3DSA:1.10.1200.10 1572 1673 1.4E-22 T 29-03-2018 SMALA_RS06450 ec0257fa1046b3cf74eb91de2204cfe1 1944 Gene3D G3DSA:3.40.50.1820 1675 1944 2.7E-19 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS06450 ec0257fa1046b3cf74eb91de2204cfe1 1944 Gene3D G3DSA:3.40.366.10 729 846 1.6E-21 T 29-03-2018 SMALA_RS06450 ec0257fa1046b3cf74eb91de2204cfe1 1944 SMART SM00825 Beta-ketoacyl synthase 35 460 1.2E-215 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS06450 ec0257fa1046b3cf74eb91de2204cfe1 1944 Pfam PF14765 Polyketide synthase dehydratase 903 1169 3.3E-52 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS06450 ec0257fa1046b3cf74eb91de2204cfe1 1944 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1325 1527 6.6E-54 T 29-03-2018 SMALA_RS06450 ec0257fa1046b3cf74eb91de2204cfe1 1944 Pfam PF08659 KR domain 1326 1500 3.3E-59 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS06450 ec0257fa1046b3cf74eb91de2204cfe1 1944 SUPERFAMILY SSF55048 673 733 6.8E-9 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS06450 ec0257fa1046b3cf74eb91de2204cfe1 1944 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 33 283 1.6E-90 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS06450 ec0257fa1046b3cf74eb91de2204cfe1 1944 Gene3D G3DSA:3.40.366.10 536 728 3.2E-56 T 29-03-2018 SMALA_RS06450 ec0257fa1046b3cf74eb91de2204cfe1 1944 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 409 526 4.8E-16 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS06450 ec0257fa1046b3cf74eb91de2204cfe1 1944 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 291 406 9.4E-45 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS06450 ec0257fa1046b3cf74eb91de2204cfe1 1944 SMART SM00824 Thioesterase 1733 1940 7.1E-95 T 29-03-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 SMALA_RS06450 ec0257fa1046b3cf74eb91de2204cfe1 1944 SMART SM00823 Phosphopantetheine attachment site 1593 1665 2.7E-32 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS06450 ec0257fa1046b3cf74eb91de2204cfe1 1944 Gene3D G3DSA:3.10.129.10 902 1023 2.5E-8 T 29-03-2018 SMALA_RS08840 e6600700d189fa9b55ff1968bcb5df18 179 Gene3D G3DSA:3.90.280.10 6 176 1.0E-50 T 29-03-2018 IPR008914 Phosphatidylethanolamine-binding protein SMALA_RS08840 e6600700d189fa9b55ff1968bcb5df18 179 SUPERFAMILY SSF49777 20 175 1.44E-52 T 29-03-2018 IPR008914 Phosphatidylethanolamine-binding protein SMALA_RS08840 e6600700d189fa9b55ff1968bcb5df18 179 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 39 170 4.3E-42 T 29-03-2018 IPR005247 YbhB/YbcL SMALA_RS08840 e6600700d189fa9b55ff1968bcb5df18 179 Pfam PF01161 Phosphatidylethanolamine-binding protein 40 173 9.6E-39 T 29-03-2018 IPR008914 Phosphatidylethanolamine-binding protein SMALA_RS00855 e5cdd1f3bcd53f361ee04a04ce449d23 265 PIRSF PIRSF000126 7 262 8.4E-55 T 29-03-2018 SMALA_RS00855 e5cdd1f3bcd53f361ee04a04ce449d23 265 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 22 207 6.2E-4 T 29-03-2018 SMALA_RS00855 e5cdd1f3bcd53f361ee04a04ce449d23 265 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 164 1.4E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS00855 e5cdd1f3bcd53f361ee04a04ce449d23 265 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 176 195 1.4E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS00855 e5cdd1f3bcd53f361ee04a04ce449d23 265 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 97 108 1.4E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS00855 e5cdd1f3bcd53f361ee04a04ce449d23 265 Gene3D G3DSA:3.40.50.720 60 259 3.7E-51 T 29-03-2018 SMALA_RS00855 e5cdd1f3bcd53f361ee04a04ce449d23 265 Gene3D G3DSA:3.40.50.720 15 59 2.0E-11 T 29-03-2018 SMALA_RS00855 e5cdd1f3bcd53f361ee04a04ce449d23 265 Pfam PF00106 short chain dehydrogenase 23 218 2.0E-55 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS00855 e5cdd1f3bcd53f361ee04a04ce449d23 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 166 1.2E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS00855 e5cdd1f3bcd53f361ee04a04ce449d23 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 195 1.2E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS00855 e5cdd1f3bcd53f361ee04a04ce449d23 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 97 108 1.2E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS00855 e5cdd1f3bcd53f361ee04a04ce449d23 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 197 214 1.2E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS00855 e5cdd1f3bcd53f361ee04a04ce449d23 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 227 247 1.2E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS00855 e5cdd1f3bcd53f361ee04a04ce449d23 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 23 40 1.2E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS00855 e5cdd1f3bcd53f361ee04a04ce449d23 265 SUPERFAMILY SSF51735 18 249 4.87E-67 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS00855 e5cdd1f3bcd53f361ee04a04ce449d23 265 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 163 191 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMALA_RS37455 71225679131d2d56d1e2250667351a8d 170 Pfam PF01750 Hydrogenase maturation protease 47 146 3.0E-10 T 29-03-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 SMALA_RS37455 71225679131d2d56d1e2250667351a8d 170 SUPERFAMILY SSF53163 4 151 5.23E-29 T 29-03-2018 IPR023430 Peptidase HybD-like domain SMALA_RS37455 71225679131d2d56d1e2250667351a8d 170 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 6 146 7.1E-29 T 29-03-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 SMALA_RS37455 71225679131d2d56d1e2250667351a8d 170 Gene3D G3DSA:3.40.50.1450 1 161 5.8E-35 T 29-03-2018 IPR023430 Peptidase HybD-like domain SMALA_RS36720 f3ed7ebd8ecba62518151fa5b724fd45 1701 SMART SM01294 1548 1615 8.3E-6 T 29-03-2018 SMALA_RS36720 f3ed7ebd8ecba62518151fa5b724fd45 1701 SUPERFAMILY SSF51735 1005 1211 4.57E-51 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS36720 f3ed7ebd8ecba62518151fa5b724fd45 1701 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 299 416 1.3E-42 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS36720 f3ed7ebd8ecba62518151fa5b724fd45 1701 Pfam PF08659 KR domain 1226 1405 1.5E-29 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS36720 f3ed7ebd8ecba62518151fa5b724fd45 1701 Gene3D G3DSA:3.30.70.250 724 769 2.2E-16 T 29-03-2018 SMALA_RS36720 f3ed7ebd8ecba62518151fa5b724fd45 1701 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 589 889 8.2E-116 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS36720 f3ed7ebd8ecba62518151fa5b724fd45 1701 Gene3D G3DSA:3.40.366.10 584 723 6.0E-44 T 29-03-2018 SMALA_RS36720 f3ed7ebd8ecba62518151fa5b724fd45 1701 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1226 1407 2.4E-15 T 29-03-2018 SMALA_RS36720 f3ed7ebd8ecba62518151fa5b724fd45 1701 Gene3D G3DSA:3.40.50.720 1219 1512 1.9E-31 T 29-03-2018 SMALA_RS36720 f3ed7ebd8ecba62518151fa5b724fd45 1701 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 35 291 9.3E-89 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS36720 f3ed7ebd8ecba62518151fa5b724fd45 1701 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 204 220 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS36720 f3ed7ebd8ecba62518151fa5b724fd45 1701 Gene3D G3DSA:3.40.47.10 306 467 2.4E-61 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS36720 f3ed7ebd8ecba62518151fa5b724fd45 1701 Pfam PF08990 Erythronolide synthase docking 4 28 9.7E-12 T 29-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 SMALA_RS36720 f3ed7ebd8ecba62518151fa5b724fd45 1701 SUPERFAMILY SSF47336 1541 1628 2.88E-23 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS36720 f3ed7ebd8ecba62518151fa5b724fd45 1701 Gene3D G3DSA:3.40.47.10 27 303 7.6E-88 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS36720 f3ed7ebd8ecba62518151fa5b724fd45 1701 Pfam PF00550 Phosphopantetheine attachment site 1550 1615 2.2E-15 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS36720 f3ed7ebd8ecba62518151fa5b724fd45 1701 SMART SM00825 Beta-ketoacyl synthase 37 469 1.8E-222 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS36720 f3ed7ebd8ecba62518151fa5b724fd45 1701 SUPERFAMILY SSF52151 781 882 3.14E-66 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS36720 f3ed7ebd8ecba62518151fa5b724fd45 1701 SUPERFAMILY SSF52151 587 714 3.14E-66 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS36720 f3ed7ebd8ecba62518151fa5b724fd45 1701 Gene3D G3DSA:3.40.50.10090 1024 1161 0.33 T 29-03-2018 SMALA_RS36720 f3ed7ebd8ecba62518151fa5b724fd45 1701 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1574 1589 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS36720 f3ed7ebd8ecba62518151fa5b724fd45 1701 Gene3D G3DSA:3.40.366.10 770 890 3.4E-27 T 29-03-2018 SMALA_RS36720 f3ed7ebd8ecba62518151fa5b724fd45 1701 SMART SM00823 Phosphopantetheine attachment site 1547 1619 1.5E-36 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS36720 f3ed7ebd8ecba62518151fa5b724fd45 1701 SUPERFAMILY SSF55048 712 780 1.7E-11 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS36720 f3ed7ebd8ecba62518151fa5b724fd45 1701 Pfam PF00698 Acyl transferase domain 588 908 8.1E-88 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS36720 f3ed7ebd8ecba62518151fa5b724fd45 1701 SUPERFAMILY SSF101173 3 35 1.22E-9 T 29-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 SMALA_RS36720 f3ed7ebd8ecba62518151fa5b724fd45 1701 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 419 549 8.4E-16 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS36720 f3ed7ebd8ecba62518151fa5b724fd45 1701 Gene3D G3DSA:1.10.1200.10 1541 1690 6.3E-23 T 29-03-2018 SMALA_RS36720 f3ed7ebd8ecba62518151fa5b724fd45 1701 SUPERFAMILY SSF53901 31 407 2.08E-100 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS36720 f3ed7ebd8ecba62518151fa5b724fd45 1701 SUPERFAMILY SSF51735 1224 1413 1.82E-27 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS36720 f3ed7ebd8ecba62518151fa5b724fd45 1701 SUPERFAMILY SSF51735 1447 1480 1.82E-27 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS36595 d8e8cddf898dd2c12e96977f59fcd0b4 251 Pfam PF00975 Thioesterase domain 24 245 3.0E-56 T 29-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 SMALA_RS36595 d8e8cddf898dd2c12e96977f59fcd0b4 251 SUPERFAMILY SSF53474 8 247 6.1E-54 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS36595 d8e8cddf898dd2c12e96977f59fcd0b4 251 Gene3D G3DSA:3.40.50.1820 4 250 5.8E-37 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS36595 d8e8cddf898dd2c12e96977f59fcd0b4 251 SMART SM00824 Thioesterase 26 247 1.3E-4 T 29-03-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 SMALA_RS35380 130d015f10d668fd309351f107a49ca0 247 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 243 1.7E-43 T 29-03-2018 SMALA_RS35380 130d015f10d668fd309351f107a49ca0 247 SUPERFAMILY SSF51735 2 243 3.19E-58 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS35380 130d015f10d668fd309351f107a49ca0 247 Gene3D G3DSA:3.40.50.720 1 39 2.8E-6 T 29-03-2018 SMALA_RS35380 130d015f10d668fd309351f107a49ca0 247 Gene3D G3DSA:3.40.50.720 40 247 1.0E-51 T 29-03-2018 SMALA_RS35380 130d015f10d668fd309351f107a49ca0 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.4E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS35380 130d015f10d668fd309351f107a49ca0 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 1.4E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS35380 130d015f10d668fd309351f107a49ca0 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 1.4E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS35380 130d015f10d668fd309351f107a49ca0 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 227 1.4E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS35380 130d015f10d668fd309351f107a49ca0 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 1.4E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS35380 130d015f10d668fd309351f107a49ca0 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 1.4E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS35380 130d015f10d668fd309351f107a49ca0 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 3.8E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS35380 130d015f10d668fd309351f107a49ca0 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 3.8E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS35380 130d015f10d668fd309351f107a49ca0 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 170 3.8E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS36530 3e4d45e9faa7c2d87eb6af9e56d2f17d 415 TIGRFAM TIGR01885 Orn_aminotrans: ornithine--oxo-acid transaminase 21 414 9.4E-148 T 29-03-2018 IPR010164 Ornithine aminotransferase GO:0004587 KEGG: 00330+2.6.1.13|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|MetaCyc: PWY-6922|Reactome: R-HSA-70614 SMALA_RS36530 3e4d45e9faa7c2d87eb6af9e56d2f17d 415 Gene3D G3DSA:3.40.640.10 196 310 4.8E-42 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS36530 3e4d45e9faa7c2d87eb6af9e56d2f17d 415 Gene3D G3DSA:3.90.1150.10 311 415 8.6E-15 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS36530 3e4d45e9faa7c2d87eb6af9e56d2f17d 415 PIRSF PIRSF000521 4 169 2.8E-8 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMALA_RS36530 3e4d45e9faa7c2d87eb6af9e56d2f17d 415 PIRSF PIRSF000521 190 415 9.6E-27 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMALA_RS36530 3e4d45e9faa7c2d87eb6af9e56d2f17d 415 SUPERFAMILY SSF53383 19 414 4.21E-116 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS36530 3e4d45e9faa7c2d87eb6af9e56d2f17d 415 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 239 276 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMALA_RS36530 3e4d45e9faa7c2d87eb6af9e56d2f17d 415 Gene3D G3DSA:3.90.1150.10 9 195 2.3E-41 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS36530 3e4d45e9faa7c2d87eb6af9e56d2f17d 415 Pfam PF00202 Aminotransferase class-III 32 414 5.3E-110 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMALA_RS04855 649909f0fde6854e354447303c397dad 285 PIRSF PIRSF020623 3 285 4.1E-80 T 29-03-2018 IPR011965 Phenylacetic acid degradation operon negative regulatory protein PaaX GO:0006351 SMALA_RS04855 649909f0fde6854e354447303c397dad 285 Pfam PF08223 PaaX-like protein C-terminal domain 183 278 1.5E-29 T 29-03-2018 IPR013225 PaaX-like, C-terminal SMALA_RS04855 649909f0fde6854e354447303c397dad 285 Pfam PF07848 PaaX-like protein 23 87 3.9E-13 T 29-03-2018 IPR012906 PaaX-like, N-terminal SMALA_RS04855 649909f0fde6854e354447303c397dad 285 Gene3D G3DSA:1.10.10.10 18 101 1.0E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS07340 8e6b13abaca699f94f8ba7b6a632ea94 318 SUPERFAMILY SSF161098 99 292 4.58E-13 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS07340 8e6b13abaca699f94f8ba7b6a632ea94 318 Gene3D G3DSA:1.10.3720.10 2 299 3.1E-34 T 29-03-2018 SMALA_RS07340 8e6b13abaca699f94f8ba7b6a632ea94 318 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 118 309 7.1E-30 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS19635 6e6889792159f6b9ae45df24765c2832 785 Gene3D G3DSA:2.60.40.10 600 696 0.0033 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS19635 6e6889792159f6b9ae45df24765c2832 785 Gene3D G3DSA:2.60.40.10 60 178 5.1E-10 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS31625 885404c8105f4f4c09b769fc1ca621d8 256 SUPERFAMILY SSF53335 8 194 4.38E-30 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS31625 885404c8105f4f4c09b769fc1ca621d8 256 Pfam PF08241 Methyltransferase domain 47 136 2.2E-16 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 SMALA_RS31625 885404c8105f4f4c09b769fc1ca621d8 256 Gene3D G3DSA:3.40.50.150 6 246 8.9E-29 T 29-03-2018 SMALA_RS19730 aaa8362f664286eb51e966c9e61ea721 294 SMART SM01350 161 294 1.2E-5 T 29-03-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 SMALA_RS19730 aaa8362f664286eb51e966c9e61ea721 294 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 161 271 1.9E-25 T 29-03-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 SMALA_RS19730 aaa8362f664286eb51e966c9e61ea721 294 SUPERFAMILY SSF51735 1 144 4.03E-42 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS19730 aaa8362f664286eb51e966c9e61ea721 294 TIGRFAM TIGR00872 gnd_rel: 6-phosphogluconate dehydrogenase (decarboxylating) 1 291 4.9E-103 T 29-03-2018 IPR004849 6-phosphogluconate dehydrogenase, YqeC-type GO:0055114 SMALA_RS19730 aaa8362f664286eb51e966c9e61ea721 294 ProSitePatterns PS00461 6-phosphogluconate dehydrogenase signature. 229 241 - T 29-03-2018 IPR006184 6-phosphogluconate-binding site GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 SMALA_RS19730 aaa8362f664286eb51e966c9e61ea721 294 SUPERFAMILY SSF48179 159 291 4.01E-41 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMALA_RS19730 aaa8362f664286eb51e966c9e61ea721 294 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 3 144 4.6E-36 T 29-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 SMALA_RS19730 aaa8362f664286eb51e966c9e61ea721 294 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 51 80 1.1E-35 T 29-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 SMALA_RS19730 aaa8362f664286eb51e966c9e61ea721 294 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 104 129 1.1E-35 T 29-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 SMALA_RS19730 aaa8362f664286eb51e966c9e61ea721 294 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 1 15 1.1E-35 T 29-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 SMALA_RS19730 aaa8362f664286eb51e966c9e61ea721 294 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 150 178 1.1E-35 T 29-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 SMALA_RS19730 aaa8362f664286eb51e966c9e61ea721 294 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 225 252 1.1E-35 T 29-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 SMALA_RS19730 aaa8362f664286eb51e966c9e61ea721 294 Gene3D G3DSA:3.40.50.720 3 169 3.0E-31 T 29-03-2018 SMALA_RS19730 aaa8362f664286eb51e966c9e61ea721 294 Gene3D G3DSA:1.10.1040.10 170 294 1.8E-40 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMALA_RS43315 aa7bf68b607c80e35804a309799d2472 205 Gene3D G3DSA:1.10.10.10 119 205 2.3E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS42240 f6616d01bbdffb0299f72ff20dcca484 349 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 238 254 - T 29-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site SMALA_RS42240 f6616d01bbdffb0299f72ff20dcca484 349 SUPERFAMILY SSF52283 14 124 2.13E-13 T 29-03-2018 SMALA_RS42240 f6616d01bbdffb0299f72ff20dcca484 349 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 135 298 4.5E-48 T 29-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 SMALA_RS42240 f6616d01bbdffb0299f72ff20dcca484 349 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 53 329 7.6E-14 T 29-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 SMALA_RS42240 f6616d01bbdffb0299f72ff20dcca484 349 SUPERFAMILY SSF51735 116 298 9.11E-45 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS42240 f6616d01bbdffb0299f72ff20dcca484 349 Gene3D G3DSA:3.40.50.720 128 299 1.0E-42 T 29-03-2018 SMALA_RS42240 f6616d01bbdffb0299f72ff20dcca484 349 Gene3D G3DSA:3.40.50.720 6 127 5.8E-15 T 29-03-2018 SMALA_RS42240 f6616d01bbdffb0299f72ff20dcca484 349 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 209 231 - T 29-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site SMALA_RS19610 78176c87ca27d8b65d5a8d19e1707c6e 886 Gene3D G3DSA:3.40.710.10 376 823 1.1E-94 T 29-03-2018 SMALA_RS19610 78176c87ca27d8b65d5a8d19e1707c6e 886 Pfam PF00912 Transglycosylase 178 352 3.5E-52 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 SMALA_RS19610 78176c87ca27d8b65d5a8d19e1707c6e 886 Pfam PF00905 Penicillin binding protein transpeptidase domain 459 719 2.2E-28 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 SMALA_RS19610 78176c87ca27d8b65d5a8d19e1707c6e 886 Gene3D G3DSA:1.10.3810.10 161 370 6.4E-60 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 SMALA_RS19610 78176c87ca27d8b65d5a8d19e1707c6e 886 SUPERFAMILY SSF53955 160 371 7.31E-58 T 29-03-2018 IPR023346 Lysozyme-like domain SMALA_RS19610 78176c87ca27d8b65d5a8d19e1707c6e 886 SUPERFAMILY SSF56601 338 357 3.82E-78 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMALA_RS19610 78176c87ca27d8b65d5a8d19e1707c6e 886 SUPERFAMILY SSF56601 542 785 3.82E-78 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMALA_RS19610 78176c87ca27d8b65d5a8d19e1707c6e 886 SUPERFAMILY SSF56601 389 515 3.82E-78 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMALA_RS29045 8977af8c41a16aba9eba553c1e836cd7 504 Pfam PF00140 Sigma-70 factor, region 1.2 206 239 7.9E-17 T 29-03-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS29045 8977af8c41a16aba9eba553c1e836cd7 504 Gene3D G3DSA:1.10.10.10 341 391 1.9E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS29045 8977af8c41a16aba9eba553c1e836cd7 504 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 267 492 1.9E-36 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS29045 8977af8c41a16aba9eba553c1e836cd7 504 Pfam PF04539 Sigma-70 region 3 350 426 1.1E-28 T 29-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS29045 8977af8c41a16aba9eba553c1e836cd7 504 SUPERFAMILY SSF88946 203 341 7.46E-54 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS29045 8977af8c41a16aba9eba553c1e836cd7 504 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 113 504 31.861 T 29-03-2018 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 SMALA_RS29045 8977af8c41a16aba9eba553c1e836cd7 504 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 295 308 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS29045 8977af8c41a16aba9eba553c1e836cd7 504 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 464 490 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS29045 8977af8c41a16aba9eba553c1e836cd7 504 SUPERFAMILY SSF88659 402 503 2.4E-27 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS29045 8977af8c41a16aba9eba553c1e836cd7 504 Gene3D G3DSA:1.10.10.10 433 504 9.5E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS29045 8977af8c41a16aba9eba553c1e836cd7 504 SUPERFAMILY SSF88659 344 417 3.74E-21 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS29045 8977af8c41a16aba9eba553c1e836cd7 504 PRINTS PR00046 Major sigma-70 factor signature 443 455 6.3E-29 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS29045 8977af8c41a16aba9eba553c1e836cd7 504 PRINTS PR00046 Major sigma-70 factor signature 295 308 6.3E-29 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS29045 8977af8c41a16aba9eba553c1e836cd7 504 PRINTS PR00046 Major sigma-70 factor signature 479 490 6.3E-29 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS29045 8977af8c41a16aba9eba553c1e836cd7 504 PRINTS PR00046 Major sigma-70 factor signature 319 327 6.3E-29 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS29045 8977af8c41a16aba9eba553c1e836cd7 504 PRINTS PR00046 Major sigma-70 factor signature 464 479 6.3E-29 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS29045 8977af8c41a16aba9eba553c1e836cd7 504 Pfam PF04545 Sigma-70, region 4 439 492 3.2E-18 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS29045 8977af8c41a16aba9eba553c1e836cd7 504 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 267 503 8.6E-113 T 29-03-2018 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 SMALA_RS29045 8977af8c41a16aba9eba553c1e836cd7 504 Gene3D G3DSA:1.10.601.10 29 340 3.2E-80 T 29-03-2018 SMALA_RS29045 8977af8c41a16aba9eba553c1e836cd7 504 Pfam PF04542 Sigma-70 region 2 271 340 2.9E-22 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS36195 ea17f86ee968fe9bb24dd183edfc5a7d 198 Pfam PF08281 Sigma-70, region 4 108 158 6.8E-10 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS36195 ea17f86ee968fe9bb24dd183edfc5a7d 198 SUPERFAMILY SSF88946 4 82 4.71E-12 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS36195 ea17f86ee968fe9bb24dd183edfc5a7d 198 Gene3D G3DSA:1.10.1740.10 2 79 6.2E-13 T 29-03-2018 SMALA_RS36195 ea17f86ee968fe9bb24dd183edfc5a7d 198 SUPERFAMILY SSF88659 107 163 6.35E-12 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS36195 ea17f86ee968fe9bb24dd183edfc5a7d 198 Gene3D G3DSA:1.10.10.10 107 194 5.1E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS36195 ea17f86ee968fe9bb24dd183edfc5a7d 198 Pfam PF04542 Sigma-70 region 2 11 76 1.0E-6 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS36195 ea17f86ee968fe9bb24dd183edfc5a7d 198 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 5 161 2.9E-16 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS11160 cef00aee04b18166a2e355bb94ae2fa1 443 SUPERFAMILY SSF48264 46 438 9.17E-54 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS11160 cef00aee04b18166a2e355bb94ae2fa1 443 PRINTS PR00359 B-class P450 signature 327 354 1.2E-17 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS11160 cef00aee04b18166a2e355bb94ae2fa1 443 PRINTS PR00359 B-class P450 signature 374 383 1.2E-17 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS11160 cef00aee04b18166a2e355bb94ae2fa1 443 PRINTS PR00359 B-class P450 signature 231 253 1.2E-17 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS11160 cef00aee04b18166a2e355bb94ae2fa1 443 PRINTS PR00359 B-class P450 signature 180 196 1.2E-17 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS11160 cef00aee04b18166a2e355bb94ae2fa1 443 PRINTS PR00359 B-class P450 signature 197 212 1.2E-17 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS11160 cef00aee04b18166a2e355bb94ae2fa1 443 Gene3D G3DSA:1.10.630.10 37 438 9.9E-35 T 29-03-2018 SMALA_RS29060 8ba39fbfd7a8ac2bf80685fcacff84a5 707 Gene3D G3DSA:3.30.565.10 35 258 1.0E-65 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS29060 8ba39fbfd7a8ac2bf80685fcacff84a5 707 SUPERFAMILY SSF55874 23 242 4.32E-59 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS29060 8ba39fbfd7a8ac2bf80685fcacff84a5 707 SMART SM00433 52 698 7.6E-281 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMALA_RS29060 8ba39fbfd7a8ac2bf80685fcacff84a5 707 PRINTS PR01159 DNA gyrase subunit B signature 229 242 4.5E-36 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SMALA_RS29060 8ba39fbfd7a8ac2bf80685fcacff84a5 707 PRINTS PR01159 DNA gyrase subunit B signature 259 281 4.5E-36 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SMALA_RS29060 8ba39fbfd7a8ac2bf80685fcacff84a5 707 PRINTS PR01159 DNA gyrase subunit B signature 674 690 4.5E-36 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SMALA_RS29060 8ba39fbfd7a8ac2bf80685fcacff84a5 707 PRINTS PR01159 DNA gyrase subunit B signature 214 229 4.5E-36 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SMALA_RS29060 8ba39fbfd7a8ac2bf80685fcacff84a5 707 PRINTS PR01159 DNA gyrase subunit B signature 23 33 4.5E-36 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SMALA_RS29060 8ba39fbfd7a8ac2bf80685fcacff84a5 707 PRINTS PR01159 DNA gyrase subunit B signature 370 386 4.5E-36 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SMALA_RS29060 8ba39fbfd7a8ac2bf80685fcacff84a5 707 PRINTS PR01159 DNA gyrase subunit B signature 532 541 4.5E-36 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SMALA_RS29060 8ba39fbfd7a8ac2bf80685fcacff84a5 707 PRINTS PR01159 DNA gyrase subunit B signature 436 456 4.5E-36 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SMALA_RS29060 8ba39fbfd7a8ac2bf80685fcacff84a5 707 PRINTS PR01159 DNA gyrase subunit B signature 658 670 4.5E-36 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SMALA_RS29060 8ba39fbfd7a8ac2bf80685fcacff84a5 707 Gene3D G3DSA:3.30.230.10 259 454 3.0E-49 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SMALA_RS29060 8ba39fbfd7a8ac2bf80685fcacff84a5 707 Pfam PF01751 Toprim domain 481 582 2.8E-14 T 29-03-2018 IPR006171 TOPRIM domain SMALA_RS29060 8ba39fbfd7a8ac2bf80685fcacff84a5 707 Gene3D G3DSA:3.40.50.670 463 703 1.7E-80 T 29-03-2018 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMALA_RS29060 8ba39fbfd7a8ac2bf80685fcacff84a5 707 ProSitePatterns PS00177 DNA topoisomerase II signature. 484 492 - T 29-03-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMALA_RS29060 8ba39fbfd7a8ac2bf80685fcacff84a5 707 Pfam PF00204 DNA gyrase B 260 452 5.2E-55 T 29-03-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMALA_RS29060 8ba39fbfd7a8ac2bf80685fcacff84a5 707 SUPERFAMILY SSF54211 260 452 1.21E-38 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SMALA_RS29060 8ba39fbfd7a8ac2bf80685fcacff84a5 707 SUPERFAMILY SSF56719 456 698 1.28E-74 T 29-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 SMALA_RS29060 8ba39fbfd7a8ac2bf80685fcacff84a5 707 PRINTS PR00418 DNA topoisomerase II family signature 326 339 5.3E-59 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMALA_RS29060 8ba39fbfd7a8ac2bf80685fcacff84a5 707 PRINTS PR00418 DNA topoisomerase II family signature 586 598 5.3E-59 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMALA_RS29060 8ba39fbfd7a8ac2bf80685fcacff84a5 707 PRINTS PR00418 DNA topoisomerase II family signature 52 67 5.3E-59 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMALA_RS29060 8ba39fbfd7a8ac2bf80685fcacff84a5 707 PRINTS PR00418 DNA topoisomerase II family signature 482 496 5.3E-59 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMALA_RS29060 8ba39fbfd7a8ac2bf80685fcacff84a5 707 PRINTS PR00418 DNA topoisomerase II family signature 87 100 5.3E-59 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMALA_RS29060 8ba39fbfd7a8ac2bf80685fcacff84a5 707 PRINTS PR00418 DNA topoisomerase II family signature 566 583 5.3E-59 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMALA_RS29060 8ba39fbfd7a8ac2bf80685fcacff84a5 707 PRINTS PR00418 DNA topoisomerase II family signature 130 144 5.3E-59 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMALA_RS29060 8ba39fbfd7a8ac2bf80685fcacff84a5 707 PRINTS PR00418 DNA topoisomerase II family signature 548 564 5.3E-59 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMALA_RS29060 8ba39fbfd7a8ac2bf80685fcacff84a5 707 PRINTS PR00418 DNA topoisomerase II family signature 637 653 5.3E-59 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMALA_RS29060 8ba39fbfd7a8ac2bf80685fcacff84a5 707 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 48 153 1.2E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS29060 8ba39fbfd7a8ac2bf80685fcacff84a5 707 SMART SM00387 48 208 1.7E-23 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS29060 8ba39fbfd7a8ac2bf80685fcacff84a5 707 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 636 693 1.5E-24 T 29-03-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 SMALA_RS13460 96783855013682b37a8a99ec71078bc9 344 Gene3D G3DSA:3.40.190.10 199 285 3.6E-19 T 29-03-2018 SMALA_RS13460 96783855013682b37a8a99ec71078bc9 344 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 96 324 2.6E-47 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SMALA_RS13460 96783855013682b37a8a99ec71078bc9 344 Gene3D G3DSA:3.40.190.10 90 198 7.8E-24 T 29-03-2018 SMALA_RS13460 96783855013682b37a8a99ec71078bc9 344 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 119 132 - T 29-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 SMALA_RS13460 96783855013682b37a8a99ec71078bc9 344 SUPERFAMILY SSF53850 94 324 3.35E-49 T 29-03-2018 SMALA_RS13460 96783855013682b37a8a99ec71078bc9 344 SMART SM00062 95 327 2.2E-48 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SMALA_RS23410 c5a76ede0be9718b49384e866408aedb 488 Pfam PF01839 FG-GAP repeat 116 153 5.5E-5 T 29-03-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 SMALA_RS23410 c5a76ede0be9718b49384e866408aedb 488 Pfam PF01839 FG-GAP repeat 350 383 1.9E-5 T 29-03-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 SMALA_RS23410 c5a76ede0be9718b49384e866408aedb 488 Pfam PF01839 FG-GAP repeat 415 448 2.4E-8 T 29-03-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 SMALA_RS23410 c5a76ede0be9718b49384e866408aedb 488 SUPERFAMILY SSF69318 289 479 1.06E-23 T 29-03-2018 SMALA_RS23410 c5a76ede0be9718b49384e866408aedb 488 Gene3D G3DSA:2.130.10.130 248 354 6.0E-17 T 29-03-2018 SMALA_RS23410 c5a76ede0be9718b49384e866408aedb 488 Gene3D G3DSA:2.130.10.130 103 247 2.8E-23 T 29-03-2018 SMALA_RS23410 c5a76ede0be9718b49384e866408aedb 488 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 187 250 1.3E-6 T 29-03-2018 SMALA_RS23410 c5a76ede0be9718b49384e866408aedb 488 SUPERFAMILY SSF69318 42 276 5.41E-32 T 29-03-2018 SMALA_RS23410 c5a76ede0be9718b49384e866408aedb 488 PRINTS PR01185 Integrin alpha subunit signature 109 129 9.3E-7 T 29-03-2018 IPR000413 Integrin alpha chain GO:0007155|GO:0008305 Reactome: R-HSA-216083 SMALA_RS23410 c5a76ede0be9718b49384e866408aedb 488 PRINTS PR01185 Integrin alpha subunit signature 177 201 9.3E-7 T 29-03-2018 IPR000413 Integrin alpha chain GO:0007155|GO:0008305 Reactome: R-HSA-216083 SMALA_RS23410 c5a76ede0be9718b49384e866408aedb 488 PRINTS PR01185 Integrin alpha subunit signature 231 252 9.3E-7 T 29-03-2018 IPR000413 Integrin alpha chain GO:0007155|GO:0008305 Reactome: R-HSA-216083 SMALA_RS23410 c5a76ede0be9718b49384e866408aedb 488 Gene3D G3DSA:2.130.10.130 15 102 2.3E-4 T 29-03-2018 SMALA_RS23410 c5a76ede0be9718b49384e866408aedb 488 Gene3D G3DSA:2.130.10.130 355 485 2.6E-17 T 29-03-2018 SMALA_RS23410 c5a76ede0be9718b49384e866408aedb 488 SMART SM00191 411 465 1.6E-5 T 29-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMALA_RS23410 c5a76ede0be9718b49384e866408aedb 488 SMART SM00191 340 399 35.0 T 29-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMALA_RS23410 c5a76ede0be9718b49384e866408aedb 488 SMART SM00191 112 172 0.0039 T 29-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMALA_RS23410 c5a76ede0be9718b49384e866408aedb 488 SMART SM00191 42 100 8.6 T 29-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMALA_RS30825 62b4256f3805fd01f2c9c106942749a7 170 SUPERFAMILY SSF46767 78 158 1.03E-32 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 SMALA_RS30825 62b4256f3805fd01f2c9c106942749a7 170 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 6 75 1.3E-7 T 29-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 SMALA_RS30825 62b4256f3805fd01f2c9c106942749a7 170 Gene3D G3DSA:1.10.10.10 74 161 1.4E-35 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS30825 62b4256f3805fd01f2c9c106942749a7 170 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 7 159 42.115 T 29-03-2018 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 SMALA_RS30825 62b4256f3805fd01f2c9c106942749a7 170 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 79 158 8.1E-35 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 SMALA_RS30825 62b4256f3805fd01f2c9c106942749a7 170 SUPERFAMILY SSF53155 5 84 2.94E-18 T 29-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 SMALA_RS30825 62b4256f3805fd01f2c9c106942749a7 170 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 80 158 7.7E-33 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 SMALA_RS30825 62b4256f3805fd01f2c9c106942749a7 170 Gene3D G3DSA:3.30.160.70 1 73 1.9E-22 T 29-03-2018 SMALA_RS30825 62b4256f3805fd01f2c9c106942749a7 170 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 129 135 - T 29-03-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 SMALA_RS31370 96e287502fb04c409dfcdd64262a15c2 854 Pfam PF03422 Carbohydrate binding module (family 6) 730 851 6.3E-30 T 29-03-2018 IPR005084 Carbohydrate binding module family 6 GO:0030246 SMALA_RS31370 96e287502fb04c409dfcdd64262a15c2 854 SUPERFAMILY SSF49299 533 618 3.53E-23 T 29-03-2018 IPR000601 PKD domain SMALA_RS31370 96e287502fb04c409dfcdd64262a15c2 854 Pfam PF07995 Glucose / Sorbosone dehydrogenase 98 382 1.2E-33 T 29-03-2018 IPR012938 Glucose/Sorbosone dehydrogenase SMALA_RS31370 96e287502fb04c409dfcdd64262a15c2 854 SUPERFAMILY SSF49785 724 851 6.2E-23 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS31370 96e287502fb04c409dfcdd64262a15c2 854 SMART SM00089 535 618 1.7E-21 T 29-03-2018 IPR022409 PKD/Chitinase domain SMALA_RS31370 96e287502fb04c409dfcdd64262a15c2 854 Gene3D G3DSA:2.120.10.30 68 528 4.5E-82 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like SMALA_RS31370 96e287502fb04c409dfcdd64262a15c2 854 Pfam PF00801 PKD domain 540 603 1.2E-13 T 29-03-2018 IPR000601 PKD domain SMALA_RS31370 96e287502fb04c409dfcdd64262a15c2 854 Gene3D G3DSA:2.60.120.260 722 853 1.8E-23 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS31370 96e287502fb04c409dfcdd64262a15c2 854 SUPERFAMILY SSF50952 433 510 2.09E-23 T 29-03-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 SMALA_RS31370 96e287502fb04c409dfcdd64262a15c2 854 SUPERFAMILY SSF50952 81 398 2.09E-23 T 29-03-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 SMALA_RS31370 96e287502fb04c409dfcdd64262a15c2 854 Gene3D G3DSA:2.60.40.10 614 721 0.034 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS31370 96e287502fb04c409dfcdd64262a15c2 854 Gene3D G3DSA:2.60.40.10 529 613 5.4E-22 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS31370 96e287502fb04c409dfcdd64262a15c2 854 SMART SM00606 722 853 1.8E-41 T 29-03-2018 IPR006584 Cellulose binding, type IV GO:0030246 SMALA_RS39360 86f97253bd73124589040f9d21f14f29 241 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 11 193 4.5E-32 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal SMALA_RS39360 86f97253bd73124589040f9d21f14f29 241 SMART SM01007 9 194 1.3E-29 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal SMALA_RS39360 86f97253bd73124589040f9d21f14f29 241 Gene3D G3DSA:3.40.225.10 2 240 2.1E-42 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal SMALA_RS39360 86f97253bd73124589040f9d21f14f29 241 SUPERFAMILY SSF53639 6 219 4.12E-44 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal SMALA_RS11260 929f587edf4537bece1f17087b6fb6c7 181 Gene3D G3DSA:2.60.40.790 8 176 2.8E-34 T 29-03-2018 IPR008978 HSP20-like chaperone SMALA_RS11260 929f587edf4537bece1f17087b6fb6c7 181 SUPERFAMILY SSF49764 36 158 3.92E-33 T 29-03-2018 IPR008978 HSP20-like chaperone SMALA_RS11260 929f587edf4537bece1f17087b6fb6c7 181 Pfam PF00011 Hsp20/alpha crystallin family 61 158 2.2E-24 T 29-03-2018 IPR002068 Alpha crystallin/Hsp20 domain SMALA_RS27660 0af741694e505334d8577c97c34cd95d 497 Pfam PF01425 Amidase 25 471 2.6E-157 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMALA_RS27660 0af741694e505334d8577c97c34cd95d 497 ProSitePatterns PS00571 Amidases signature. 153 184 - T 29-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 SMALA_RS27660 0af741694e505334d8577c97c34cd95d 497 Gene3D G3DSA:3.90.1300.10 2 488 3.0E-169 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMALA_RS27660 0af741694e505334d8577c97c34cd95d 497 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 15 482 5.8E-188 T 29-03-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMALA_RS27660 0af741694e505334d8577c97c34cd95d 497 SUPERFAMILY SSF75304 2 482 1.16E-160 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMALA_RS27660 0af741694e505334d8577c97c34cd95d 497 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 12 483 91.052 T 29-03-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMALA_RS06105 832be66a7355193abdefcbcee19c063c 289 SUPERFAMILY SSF54593 138 277 1.48E-34 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS06105 832be66a7355193abdefcbcee19c063c 289 SUPERFAMILY SSF54593 1 122 8.53E-16 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS06105 832be66a7355193abdefcbcee19c063c 289 ProSitePatterns PS00082 Extradiol ring-cleavage dioxygenases signature. 230 251 - T 29-03-2018 IPR000486 Extradiol ring-cleavage dioxygenase, class I /II GO:0003824|GO:0006725|GO:0008198|GO:0055114 SMALA_RS06105 832be66a7355193abdefcbcee19c063c 289 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 119 1.6E-4 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMALA_RS06105 832be66a7355193abdefcbcee19c063c 289 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 142 252 1.2E-18 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMALA_RS06105 832be66a7355193abdefcbcee19c063c 289 Gene3D G3DSA:3.10.180.10 136 277 7.6E-28 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS06105 832be66a7355193abdefcbcee19c063c 289 Gene3D G3DSA:3.10.180.10 1 135 1.6E-12 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS01580 8bbb441386cf1761958ec20c69ae1b93 280 SUPERFAMILY SSF51430 10 270 2.88E-84 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS01580 8bbb441386cf1761958ec20c69ae1b93 280 Gene3D G3DSA:3.20.20.100 4 272 1.1E-81 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS01580 8bbb441386cf1761958ec20c69ae1b93 280 PRINTS PR00069 Aldo-keto reductase signature 203 227 3.2E-15 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMALA_RS01580 8bbb441386cf1761958ec20c69ae1b93 280 PRINTS PR00069 Aldo-keto reductase signature 99 117 3.2E-15 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMALA_RS01580 8bbb441386cf1761958ec20c69ae1b93 280 PRINTS PR00069 Aldo-keto reductase signature 43 67 3.2E-15 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMALA_RS01580 8bbb441386cf1761958ec20c69ae1b93 280 PRINTS PR00069 Aldo-keto reductase signature 129 146 3.2E-15 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMALA_RS01580 8bbb441386cf1761958ec20c69ae1b93 280 PIRSF PIRSF000097 1 121 7.6E-16 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMALA_RS01580 8bbb441386cf1761958ec20c69ae1b93 280 PIRSF PIRSF000097 117 267 7.4E-20 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMALA_RS01580 8bbb441386cf1761958ec20c69ae1b93 280 Pfam PF00248 Aldo/keto reductase family 19 266 2.9E-57 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS24540 0eea0336f768d749ec4672bb3a2e69cd 67 Gene3D G3DSA:2.40.50.140 1 67 1.1E-26 T 29-03-2018 SMALA_RS24540 0eea0336f768d749ec4672bb3a2e69cd 67 PRINTS PR00050 Cold shock protein signature 4 19 3.5E-16 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMALA_RS24540 0eea0336f768d749ec4672bb3a2e69cd 67 PRINTS PR00050 Cold shock protein signature 25 34 3.5E-16 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMALA_RS24540 0eea0336f768d749ec4672bb3a2e69cd 67 PRINTS PR00050 Cold shock protein signature 40 58 3.5E-16 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMALA_RS24540 0eea0336f768d749ec4672bb3a2e69cd 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 8.5E-28 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMALA_RS24540 0eea0336f768d749ec4672bb3a2e69cd 67 SMART SM00357 3 67 5.0E-29 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 SMALA_RS24540 0eea0336f768d749ec4672bb3a2e69cd 67 SUPERFAMILY SSF50249 1 66 2.42E-23 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMALA_RS24540 0eea0336f768d749ec4672bb3a2e69cd 67 PIRSF PIRSF002599 1 67 7.6E-24 T 29-03-2018 IPR012156 Cold shock, CspA GO:0003676 SMALA_RS24540 0eea0336f768d749ec4672bb3a2e69cd 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 29-03-2018 IPR019844 Cold-shock conserved site SMALA_RS39655 c1effdbe512d3a7250c78c6abd4437c1 275 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS39655 c1effdbe512d3a7250c78c6abd4437c1 275 SMART SM00382 30 230 5.7E-20 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS39655 c1effdbe512d3a7250c78c6abd4437c1 275 Gene3D G3DSA:3.40.50.300 1 269 1.0E-73 T 29-03-2018 SMALA_RS39655 c1effdbe512d3a7250c78c6abd4437c1 275 Pfam PF00005 ABC transporter 23 173 1.8E-35 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS39655 c1effdbe512d3a7250c78c6abd4437c1 275 SUPERFAMILY SSF52540 2 244 3.4E-70 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS30245 d05f80cef4d79f9909171c37ebac3618 270 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS30245 d05f80cef4d79f9909171c37ebac3618 270 Gene3D G3DSA:3.40.50.300 23 238 2.6E-59 T 29-03-2018 SMALA_RS30245 d05f80cef4d79f9909171c37ebac3618 270 SMART SM00382 54 228 8.9E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS30245 d05f80cef4d79f9909171c37ebac3618 270 SUPERFAMILY SSF52540 26 248 7.61E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS30245 d05f80cef4d79f9909171c37ebac3618 270 Pfam PF00005 ABC transporter 45 178 4.7E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS38555 6d64daf9cb08b66b3916372a3dbec9f9 336 Pfam PF12833 Helix-turn-helix domain 244 323 1.4E-20 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS38555 6d64daf9cb08b66b3916372a3dbec9f9 336 SUPERFAMILY SSF52317 13 202 1.95E-49 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS38555 6d64daf9cb08b66b3916372a3dbec9f9 336 SUPERFAMILY SSF46689 274 326 1.43E-9 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS38555 6d64daf9cb08b66b3916372a3dbec9f9 336 Gene3D G3DSA:1.10.10.60 221 273 3.8E-10 T 29-03-2018 SMALA_RS38555 6d64daf9cb08b66b3916372a3dbec9f9 336 Gene3D G3DSA:3.40.50.880 9 220 1.1E-57 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS38555 6d64daf9cb08b66b3916372a3dbec9f9 336 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 275 317 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 SMALA_RS38555 6d64daf9cb08b66b3916372a3dbec9f9 336 Pfam PF01965 DJ-1/PfpI family 14 183 5.9E-25 T 29-03-2018 IPR002818 DJ-1/PfpI SMALA_RS38555 6d64daf9cb08b66b3916372a3dbec9f9 336 SUPERFAMILY SSF46689 221 271 6.72E-7 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS38555 6d64daf9cb08b66b3916372a3dbec9f9 336 SMART SM00342 238 321 8.7E-25 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS38555 6d64daf9cb08b66b3916372a3dbec9f9 336 Gene3D G3DSA:1.10.10.60 274 328 2.1E-12 T 29-03-2018 SMALA_RS41950 f9c7f0cb218e87808cb1247299212d4f 435 Pfam PF13556 PucR C-terminal helix-turn-helix domain 368 426 2.9E-19 T 29-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain SMALA_RS41950 f9c7f0cb218e87808cb1247299212d4f 435 SUPERFAMILY SSF46689 335 403 2.46E-5 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS41950 f9c7f0cb218e87808cb1247299212d4f 435 Gene3D G3DSA:1.10.10.60 342 402 5.1E-8 T 29-03-2018 SMALA_RS41950 f9c7f0cb218e87808cb1247299212d4f 435 Gene3D G3DSA:3.30.450.40 5 179 5.1E-4 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS00865 572fd2980a69a3e5e4c660508efcb2ba 332 SUPERFAMILY SSF82549 12 331 7.85E-99 T 29-03-2018 SMALA_RS00865 572fd2980a69a3e5e4c660508efcb2ba 332 Pfam PF02733 Dak1 domain 19 329 9.8E-105 T 29-03-2018 IPR004006 DhaK domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 SMALA_RS00865 572fd2980a69a3e5e4c660508efcb2ba 332 Gene3D G3DSA:3.30.1180.20 186 332 7.5E-39 T 29-03-2018 SMALA_RS00865 572fd2980a69a3e5e4c660508efcb2ba 332 Gene3D G3DSA:3.40.50.10440 12 185 4.9E-61 T 29-03-2018 SMALA_RS35120 24a59de5bf21642f8a9338b909cda4c8 315 Gene3D G3DSA:1.20.58.370 15 58 7.9E-4 T 29-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain SMALA_RS35120 24a59de5bf21642f8a9338b909cda4c8 315 SUPERFAMILY SSF161098 76 301 1.96E-42 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS35120 24a59de5bf21642f8a9338b909cda4c8 315 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 313 1.6E-15 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS35120 24a59de5bf21642f8a9338b909cda4c8 315 Gene3D G3DSA:1.10.3720.10 84 312 5.2E-36 T 29-03-2018 SMALA_RS08130 c048671752b01dd9c3dc746a3af57934 200 Gene3D G3DSA:1.10.10.60 2 62 5.8E-23 T 29-03-2018 SMALA_RS08130 c048671752b01dd9c3dc746a3af57934 200 SUPERFAMILY SSF48498 88 199 3.06E-19 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS08130 c048671752b01dd9c3dc746a3af57934 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 6.1E-14 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS08130 c048671752b01dd9c3dc746a3af57934 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 6.1E-14 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS08130 c048671752b01dd9c3dc746a3af57934 200 SUPERFAMILY SSF46689 7 90 9.23E-23 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS08130 c048671752b01dd9c3dc746a3af57934 200 ProSitePatterns PS01081 TetR-type HTH domain signature. 31 62 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site SMALA_RS08130 c048671752b01dd9c3dc746a3af57934 200 Gene3D G3DSA:1.10.357.10 63 200 2.1E-24 T 29-03-2018 SMALA_RS08130 c048671752b01dd9c3dc746a3af57934 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 65 3.7E-23 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS42280 b0984e5f6bdb0b58602516f1e4a0555d 398 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 3 128 8.0E-5 T 29-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain SMALA_RS42280 b0984e5f6bdb0b58602516f1e4a0555d 398 SUPERFAMILY SSF51604 147 372 6.55E-37 T 29-03-2018 IPR029065 Enolase C-terminal domain-like SMALA_RS42280 b0984e5f6bdb0b58602516f1e4a0555d 398 SUPERFAMILY SSF54826 4 130 1.17E-18 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMALA_RS42280 b0984e5f6bdb0b58602516f1e4a0555d 398 Gene3D G3DSA:3.20.20.120 142 371 2.3E-37 T 29-03-2018 IPR029065 Enolase C-terminal domain-like SMALA_RS42280 b0984e5f6bdb0b58602516f1e4a0555d 398 Gene3D G3DSA:3.30.390.10 3 138 3.1E-22 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMALA_RS42280 b0984e5f6bdb0b58602516f1e4a0555d 398 SMART SM00922 159 255 2.6E-9 T 29-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal SMALA_RS42280 b0984e5f6bdb0b58602516f1e4a0555d 398 Pfam PF13378 Enolase C-terminal domain-like 173 372 9.6E-33 T 29-03-2018 IPR029065 Enolase C-terminal domain-like SMALA_RS36915 65b0b17458020a360f3b939735df73ca 484 Gene3D G3DSA:1.20.5.320 444 484 8.7E-17 T 29-03-2018 SMALA_RS36915 65b0b17458020a360f3b939735df73ca 484 SUPERFAMILY SSF48179 184 477 1.46E-116 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMALA_RS36915 65b0b17458020a360f3b939735df73ca 484 ProSitePatterns PS00461 6-phosphogluconate dehydrogenase signature. 261 273 - T 29-03-2018 IPR006184 6-phosphogluconate-binding site GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 SMALA_RS36915 65b0b17458020a360f3b939735df73ca 484 SUPERFAMILY SSF51735 11 184 1.11E-52 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS36915 65b0b17458020a360f3b939735df73ca 484 SMART SM01350 186 476 1.7E-199 T 29-03-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 SMALA_RS36915 65b0b17458020a360f3b939735df73ca 484 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 186 475 9.2E-122 T 29-03-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 SMALA_RS36915 65b0b17458020a360f3b939735df73ca 484 PIRSF PIRSF000109 5 483 9.3E-199 T 29-03-2018 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 SMALA_RS36915 65b0b17458020a360f3b939735df73ca 484 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 365 387 7.2E-82 T 29-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 SMALA_RS36915 65b0b17458020a360f3b939735df73ca 484 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 11 34 7.2E-82 T 29-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 SMALA_RS36915 65b0b17458020a360f3b939735df73ca 484 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 74 103 7.2E-82 T 29-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 SMALA_RS36915 65b0b17458020a360f3b939735df73ca 484 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 175 203 7.2E-82 T 29-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 SMALA_RS36915 65b0b17458020a360f3b939735df73ca 484 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 257 284 7.2E-82 T 29-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 SMALA_RS36915 65b0b17458020a360f3b939735df73ca 484 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 127 152 7.2E-82 T 29-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 SMALA_RS36915 65b0b17458020a360f3b939735df73ca 484 TIGRFAM TIGR00873 gnd: 6-phosphogluconate dehydrogenase (decarboxylating) 12 475 4.5E-204 T 29-03-2018 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 SMALA_RS36915 65b0b17458020a360f3b939735df73ca 484 Gene3D G3DSA:1.10.1040.10 188 443 1.0E-103 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMALA_RS36915 65b0b17458020a360f3b939735df73ca 484 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 12 179 2.4E-50 T 29-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 SMALA_RS36915 65b0b17458020a360f3b939735df73ca 484 Gene3D G3DSA:3.40.50.720 7 187 6.0E-38 T 29-03-2018 SMALA_RS14525 f8a2e3ff5270046ec72a26e78a8fdf0f 274 SUPERFAMILY SSF46894 2 98 1.08E-11 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS14525 f8a2e3ff5270046ec72a26e78a8fdf0f 274 Gene3D G3DSA:1.25.40.10 102 259 6.4E-25 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS14525 f8a2e3ff5270046ec72a26e78a8fdf0f 274 Pfam PF00486 Transcriptional regulatory protein, C terminal 23 98 8.5E-8 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS14525 f8a2e3ff5270046ec72a26e78a8fdf0f 274 Pfam PF03704 Bacterial transcriptional activator domain 105 250 2.0E-46 T 29-03-2018 IPR005158 Bacterial transcriptional activator domain SMALA_RS14525 f8a2e3ff5270046ec72a26e78a8fdf0f 274 SUPERFAMILY SSF48452 102 258 5.31E-38 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS14525 f8a2e3ff5270046ec72a26e78a8fdf0f 274 Gene3D G3DSA:1.10.10.10 1 101 6.4E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS14525 f8a2e3ff5270046ec72a26e78a8fdf0f 274 SMART SM00862 15 98 2.1E-4 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS14525 f8a2e3ff5270046ec72a26e78a8fdf0f 274 SMART SM01043 105 250 3.1E-52 T 29-03-2018 IPR005158 Bacterial transcriptional activator domain SMALA_RS28780 1fc476e8ffb499766651aeac45c217cd 1554 Gene3D G3DSA:1.10.10.10 1022 1083 0.028 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS28780 1fc476e8ffb499766651aeac45c217cd 1554 SMART SM00487 20 239 5.2E-37 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain SMALA_RS28780 1fc476e8ffb499766651aeac45c217cd 1554 Pfam PF00271 Helicase conserved C-terminal domain 277 401 1.6E-11 T 29-03-2018 IPR001650 Helicase, C-terminal SMALA_RS28780 1fc476e8ffb499766651aeac45c217cd 1554 Pfam PF00270 DEAD/DEAH box helicase 25 210 3.9E-27 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 SMALA_RS28780 1fc476e8ffb499766651aeac45c217cd 1554 SUPERFAMILY SSF52540 332 410 2.98E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS28780 1fc476e8ffb499766651aeac45c217cd 1554 SUPERFAMILY SSF52540 34 210 2.98E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS28780 1fc476e8ffb499766651aeac45c217cd 1554 SUPERFAMILY SSF52540 246 301 2.98E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS28780 1fc476e8ffb499766651aeac45c217cd 1554 Gene3D G3DSA:3.40.50.300 257 431 9.0E-27 T 29-03-2018 SMALA_RS28780 1fc476e8ffb499766651aeac45c217cd 1554 SMART SM00490 320 401 5.9E-13 T 29-03-2018 IPR001650 Helicase, C-terminal SMALA_RS28780 1fc476e8ffb499766651aeac45c217cd 1554 Gene3D G3DSA:3.40.50.300 11 239 5.1E-37 T 29-03-2018 SMALA_RS28780 1fc476e8ffb499766651aeac45c217cd 1554 Pfam PF08494 DEAD/H associated 665 874 8.3E-78 T 29-03-2018 IPR013701 DEAD/H associated GO:0005524|GO:0016818 SMALA_RS14365 22868b9809670a156de2bceb8ea32358 125 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS14365 22868b9809670a156de2bceb8ea32358 125 SUPERFAMILY SSF46955 2 113 3.52E-26 T 29-03-2018 IPR009061 Putative DNA-binding domain SMALA_RS14365 22868b9809670a156de2bceb8ea32358 125 Gene3D G3DSA:1.10.1660.10 1 54 3.4E-19 T 29-03-2018 SMALA_RS14365 22868b9809670a156de2bceb8ea32358 125 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 5.3E-8 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS14365 22868b9809670a156de2bceb8ea32358 125 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 5.3E-8 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS14365 22868b9809670a156de2bceb8ea32358 125 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 5.3E-8 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS14365 22868b9809670a156de2bceb8ea32358 125 Gene3D G3DSA:1.10.1660.10 55 123 2.4E-11 T 29-03-2018 SMALA_RS14365 22868b9809670a156de2bceb8ea32358 125 Pfam PF13411 MerR HTH family regulatory protein 2 67 1.1E-16 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS14365 22868b9809670a156de2bceb8ea32358 125 SMART SM00422 1 69 1.2E-19 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS11035 a6ea70a5b7957c039781ac8baabcc9d6 375 SUPERFAMILY SSF50939 13 374 3.36E-80 T 29-03-2018 IPR011040 Sialidases KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 SMALA_RS11035 a6ea70a5b7957c039781ac8baabcc9d6 375 Gene3D G3DSA:2.120.10.10 5 375 1.7E-68 T 29-03-2018 SMALA_RS11035 a6ea70a5b7957c039781ac8baabcc9d6 375 Pfam PF13088 BNR repeat-like domain 38 349 2.8E-29 T 29-03-2018 IPR011040 Sialidases KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 SMALA_RS26070 904a8982a24791fe62802c1c22295b77 252 Pfam PF01987 Mitochondrial biogenesis AIM24 21 215 4.2E-30 T 29-03-2018 IPR002838 Mitochondrial biogenesis protein AIM24 SMALA_RS26070 904a8982a24791fe62802c1c22295b77 252 Gene3D G3DSA:3.60.160.10 7 227 4.0E-43 T 29-03-2018 IPR002838 Mitochondrial biogenesis protein AIM24 SMALA_RS26070 904a8982a24791fe62802c1c22295b77 252 SUPERFAMILY SSF51219 19 225 1.23E-43 T 29-03-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain SMALA_RS31435 10675b18d83de809e4d801b08b8e8f5e 560 Gene3D G3DSA:3.40.50.1220 196 348 3.8E-31 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain SMALA_RS31435 10675b18d83de809e4d801b08b8e8f5e 560 SUPERFAMILY SSF52518 9 183 4.98E-46 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold SMALA_RS31435 10675b18d83de809e4d801b08b8e8f5e 560 SUPERFAMILY SSF52518 370 552 3.22E-48 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold SMALA_RS31435 10675b18d83de809e4d801b08b8e8f5e 560 Gene3D G3DSA:3.40.50.970 2 195 6.7E-49 T 29-03-2018 SMALA_RS31435 10675b18d83de809e4d801b08b8e8f5e 560 Gene3D G3DSA:3.40.50.970 349 557 1.0E-37 T 29-03-2018 SMALA_RS31435 10675b18d83de809e4d801b08b8e8f5e 560 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 430 449 - T 29-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 SMALA_RS31435 10675b18d83de809e4d801b08b8e8f5e 560 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 394 542 8.2E-29 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 SMALA_RS31435 10675b18d83de809e4d801b08b8e8f5e 560 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 10 176 1.9E-49 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 SMALA_RS31435 10675b18d83de809e4d801b08b8e8f5e 560 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 200 326 2.6E-24 T 29-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 SMALA_RS31435 10675b18d83de809e4d801b08b8e8f5e 560 SUPERFAMILY SSF52467 195 376 3.79E-35 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain SMALA_RS06325 6a3de8c6ca5f72b6f5223ab098b55337 516 SUPERFAMILY SSF56801 3 514 4.45E-163 T 29-03-2018 SMALA_RS06325 6a3de8c6ca5f72b6f5223ab098b55337 516 Pfam PF13193 AMP-binding enzyme C-terminal domain 424 502 1.9E-18 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS06325 6a3de8c6ca5f72b6f5223ab098b55337 516 Gene3D G3DSA:2.30.38.10 321 408 1.8E-26 T 29-03-2018 SMALA_RS06325 6a3de8c6ca5f72b6f5223ab098b55337 516 Gene3D G3DSA:3.30.300.30 410 516 2.0E-29 T 29-03-2018 SMALA_RS06325 6a3de8c6ca5f72b6f5223ab098b55337 516 PRINTS PR00154 AMP-binding signature 161 172 5.9E-5 T 29-03-2018 IPR020459 AMP-binding SMALA_RS06325 6a3de8c6ca5f72b6f5223ab098b55337 516 PRINTS PR00154 AMP-binding signature 173 181 5.9E-5 T 29-03-2018 IPR020459 AMP-binding SMALA_RS06325 6a3de8c6ca5f72b6f5223ab098b55337 516 ProSitePatterns PS00455 Putative AMP-binding domain signature. 166 177 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS06325 6a3de8c6ca5f72b6f5223ab098b55337 516 Gene3D G3DSA:3.40.50.980 1 171 6.2E-48 T 29-03-2018 SMALA_RS06325 6a3de8c6ca5f72b6f5223ab098b55337 516 Gene3D G3DSA:3.40.50.980 172 320 8.8E-52 T 29-03-2018 SMALA_RS06325 6a3de8c6ca5f72b6f5223ab098b55337 516 Pfam PF00501 AMP-binding enzyme 10 414 2.9E-113 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS38320 916562d944eec347aa9d7d3ac415db9f 361 SMART SM00331 129 352 7.6E-30 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS38320 916562d944eec347aa9d7d3ac415db9f 361 Gene3D G3DSA:1.10.1660.10 60 121 6.2E-5 T 29-03-2018 SMALA_RS38320 916562d944eec347aa9d7d3ac415db9f 361 SUPERFAMILY SSF81606 123 352 1.06E-56 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS38320 916562d944eec347aa9d7d3ac415db9f 361 SUPERFAMILY SSF46955 4 107 7.33E-22 T 29-03-2018 IPR009061 Putative DNA-binding domain SMALA_RS38320 916562d944eec347aa9d7d3ac415db9f 361 SMART SM00422 4 74 1.8E-18 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS38320 916562d944eec347aa9d7d3ac415db9f 361 Pfam PF13411 MerR HTH family regulatory protein 5 72 4.1E-13 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS38320 916562d944eec347aa9d7d3ac415db9f 361 Pfam PF13672 Protein phosphatase 2C 137 307 2.1E-8 T 29-03-2018 SMALA_RS38320 916562d944eec347aa9d7d3ac415db9f 361 Gene3D G3DSA:1.10.1660.10 2 59 5.7E-18 T 29-03-2018 SMALA_RS38320 916562d944eec347aa9d7d3ac415db9f 361 SMART SM00332 114 350 1.1E-19 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS38320 916562d944eec347aa9d7d3ac415db9f 361 ProSitePatterns PS00552 MerR-type HTH domain signature. 7 29 - T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS38320 916562d944eec347aa9d7d3ac415db9f 361 Gene3D G3DSA:3.60.40.10 123 352 9.0E-36 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS33980 ebc718ddaf664cf0207158f56bfe19d1 756 Gene3D G3DSA:3.40.50.1700 373 634 3.6E-75 T 29-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 SMALA_RS33980 ebc718ddaf664cf0207158f56bfe19d1 756 SMART SM01217 672 742 6.8E-17 T 29-03-2018 IPR026891 Fibronectin type III-like domain SMALA_RS33980 ebc718ddaf664cf0207158f56bfe19d1 756 Gene3D G3DSA:3.20.20.300 2 371 5.1E-97 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SMALA_RS33980 ebc718ddaf664cf0207158f56bfe19d1 756 PRINTS PR00133 Glycosyl hydrolase family 3 signature 131 150 1.2E-21 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SMALA_RS33980 ebc718ddaf664cf0207158f56bfe19d1 756 PRINTS PR00133 Glycosyl hydrolase family 3 signature 208 224 1.2E-21 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SMALA_RS33980 ebc718ddaf664cf0207158f56bfe19d1 756 PRINTS PR00133 Glycosyl hydrolase family 3 signature 278 296 1.2E-21 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SMALA_RS33980 ebc718ddaf664cf0207158f56bfe19d1 756 PRINTS PR00133 Glycosyl hydrolase family 3 signature 108 124 1.2E-21 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SMALA_RS33980 ebc718ddaf664cf0207158f56bfe19d1 756 PRINTS PR00133 Glycosyl hydrolase family 3 signature 177 193 1.2E-21 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SMALA_RS33980 ebc718ddaf664cf0207158f56bfe19d1 756 Gene3D G3DSA:2.60.40.10 635 753 7.6E-21 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS33980 ebc718ddaf664cf0207158f56bfe19d1 756 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 87 353 7.6E-59 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SMALA_RS33980 ebc718ddaf664cf0207158f56bfe19d1 756 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 387 634 2.1E-48 T 29-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 SMALA_RS33980 ebc718ddaf664cf0207158f56bfe19d1 756 Pfam PF14310 Fibronectin type III-like domain 672 742 8.9E-12 T 29-03-2018 IPR026891 Fibronectin type III-like domain SMALA_RS33980 ebc718ddaf664cf0207158f56bfe19d1 756 SUPERFAMILY SSF52279 387 636 2.09E-47 T 29-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 SMALA_RS33980 ebc718ddaf664cf0207158f56bfe19d1 756 SUPERFAMILY SSF51445 5 44 2.21E-88 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS33980 ebc718ddaf664cf0207158f56bfe19d1 756 SUPERFAMILY SSF51445 72 370 2.21E-88 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS08515 4e3065f34cf10be8c0c045d0a3a8e2f8 358 Gene3D G3DSA:2.40.10.10 257 345 4.1E-21 T 29-03-2018 SMALA_RS08515 4e3065f34cf10be8c0c045d0a3a8e2f8 358 Gene3D G3DSA:3.30.300.50 38 96 4.3E-18 T 29-03-2018 IPR035070 Streptogrisin prodomain SMALA_RS08515 4e3065f34cf10be8c0c045d0a3a8e2f8 358 Pfam PF00089 Trypsin 198 351 4.9E-12 T 29-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 SMALA_RS08515 4e3065f34cf10be8c0c045d0a3a8e2f8 358 Gene3D G3DSA:2.40.10.10 172 256 7.3E-25 T 29-03-2018 SMALA_RS08515 4e3065f34cf10be8c0c045d0a3a8e2f8 358 Pfam PF02983 Alpha-lytic protease prodomain 100 155 4.6E-17 T 29-03-2018 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 SMALA_RS08515 4e3065f34cf10be8c0c045d0a3a8e2f8 358 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 308 319 - T 29-03-2018 IPR033116 Serine proteases, trypsin family, serine active site SMALA_RS08515 4e3065f34cf10be8c0c045d0a3a8e2f8 358 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 200 205 - T 29-03-2018 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 SMALA_RS08515 4e3065f34cf10be8c0c045d0a3a8e2f8 358 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 323 337 7.5E-47 T 29-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMALA_RS08515 4e3065f34cf10be8c0c045d0a3a8e2f8 358 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 259 279 7.5E-47 T 29-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMALA_RS08515 4e3065f34cf10be8c0c045d0a3a8e2f8 358 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 280 297 7.5E-47 T 29-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMALA_RS08515 4e3065f34cf10be8c0c045d0a3a8e2f8 358 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 198 212 7.5E-47 T 29-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMALA_RS08515 4e3065f34cf10be8c0c045d0a3a8e2f8 358 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 299 322 7.5E-47 T 29-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMALA_RS08515 4e3065f34cf10be8c0c045d0a3a8e2f8 358 PIRSF PIRSF001134 1 358 6.7E-136 T 29-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMALA_RS08515 4e3065f34cf10be8c0c045d0a3a8e2f8 358 SUPERFAMILY SSF50494 174 353 9.6E-39 T 29-03-2018 IPR009003 Peptidase S1, PA clan SMALA_RS08515 4e3065f34cf10be8c0c045d0a3a8e2f8 358 Gene3D G3DSA:3.30.300.50 97 166 6.5E-22 T 29-03-2018 IPR035070 Streptogrisin prodomain SMALA_RS29980 2ea9b2d2fde561d6a6fe528b8a753b1f 352 Gene3D G3DSA:3.90.25.10 212 349 3.7E-32 T 29-03-2018 SMALA_RS29980 2ea9b2d2fde561d6a6fe528b8a753b1f 352 SUPERFAMILY SSF51735 1 123 3.66E-78 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS29980 2ea9b2d2fde561d6a6fe528b8a753b1f 352 SUPERFAMILY SSF51735 160 345 3.66E-78 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS29980 2ea9b2d2fde561d6a6fe528b8a753b1f 352 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 267 1.1E-44 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 SMALA_RS29980 2ea9b2d2fde561d6a6fe528b8a753b1f 352 Gene3D G3DSA:3.40.50.720 1 211 2.0E-34 T 29-03-2018 SMALA_RS38845 87661e5e206f2cd4d4e56a681ae63a26 708 SMART SM00091 16 81 1.8 T 29-03-2018 IPR000014 PAS domain SMALA_RS38845 87661e5e206f2cd4d4e56a681ae63a26 708 SMART SM00091 137 203 0.025 T 29-03-2018 IPR000014 PAS domain SMALA_RS38845 87661e5e206f2cd4d4e56a681ae63a26 708 Gene3D G3DSA:3.30.450.40 257 442 1.5E-28 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS38845 87661e5e206f2cd4d4e56a681ae63a26 708 SUPERFAMILY SSF55785 141 245 9.9E-9 T 29-03-2018 IPR000014 PAS domain SMALA_RS38845 87661e5e206f2cd4d4e56a681ae63a26 708 Gene3D G3DSA:3.60.40.10 443 692 2.5E-36 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS38845 87661e5e206f2cd4d4e56a681ae63a26 708 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 495 689 1.5E-48 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS38845 87661e5e206f2cd4d4e56a681ae63a26 708 SUPERFAMILY SSF55781 384 455 4.58E-11 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS38845 87661e5e206f2cd4d4e56a681ae63a26 708 Gene3D G3DSA:3.30.450.20 27 138 1.2E-6 T 29-03-2018 SMALA_RS38845 87661e5e206f2cd4d4e56a681ae63a26 708 SMART SM00331 469 689 1.4E-33 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS38845 87661e5e206f2cd4d4e56a681ae63a26 708 Gene3D G3DSA:3.30.450.20 139 256 8.6E-12 T 29-03-2018 SMALA_RS38845 87661e5e206f2cd4d4e56a681ae63a26 708 Pfam PF01590 GAF domain 372 438 2.9E-7 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS38845 87661e5e206f2cd4d4e56a681ae63a26 708 SUPERFAMILY SSF55785 24 125 5.41E-6 T 29-03-2018 IPR000014 PAS domain SMALA_RS38845 87661e5e206f2cd4d4e56a681ae63a26 708 Pfam PF08448 PAS fold 143 247 1.5E-6 T 29-03-2018 IPR013656 PAS fold-4 SMALA_RS38845 87661e5e206f2cd4d4e56a681ae63a26 708 SUPERFAMILY SSF81606 483 688 8.37E-5 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS33970 236bedb0883b072d046be21a3b732ed4 347 Gene3D G3DSA:1.10.10.60 7 26 0.042 T 29-03-2018 SMALA_RS33970 236bedb0883b072d046be21a3b732ed4 347 Pfam PF00356 Bacterial regulatory proteins, lacI family 13 58 8.4E-11 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS33970 236bedb0883b072d046be21a3b732ed4 347 Gene3D G3DSA:1.10.260.40 27 65 9.6E-20 T 29-03-2018 SMALA_RS33970 236bedb0883b072d046be21a3b732ed4 347 Gene3D G3DSA:3.40.50.2300 192 321 1.6E-40 T 29-03-2018 SMALA_RS33970 236bedb0883b072d046be21a3b732ed4 347 SUPERFAMILY SSF47413 11 69 9.38E-14 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS33970 236bedb0883b072d046be21a3b732ed4 347 Pfam PF13377 Periplasmic binding protein-like domain 184 342 7.1E-36 T 29-03-2018 SMALA_RS33970 236bedb0883b072d046be21a3b732ed4 347 SUPERFAMILY SSF53822 85 345 5.1E-59 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SMALA_RS33970 236bedb0883b072d046be21a3b732ed4 347 Gene3D G3DSA:3.40.50.2300 66 191 2.7E-27 T 29-03-2018 SMALA_RS33970 236bedb0883b072d046be21a3b732ed4 347 SMART SM00354 11 81 5.1E-18 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS12470 878f15ba801bcc3b6a48b2623427fcf6 128 TIGRFAM TIGR02378 nirD_assim_sml: nitrite reductase [NAD(P)H], small subunit 22 118 1.5E-26 T 29-03-2018 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 SMALA_RS12470 878f15ba801bcc3b6a48b2623427fcf6 128 Pfam PF13806 Rieske-like [2Fe-2S] domain 21 118 3.5E-33 T 29-03-2018 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 SMALA_RS12470 878f15ba801bcc3b6a48b2623427fcf6 128 SUPERFAMILY SSF50022 21 118 1.79E-29 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMALA_RS12470 878f15ba801bcc3b6a48b2623427fcf6 128 Gene3D G3DSA:2.102.10.10 14 121 5.2E-17 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMALA_RS39620 f1832fa702d66509e8b499dabee6252c 578 Gene3D G3DSA:3.30.450.40 210 375 6.8E-25 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS39620 f1832fa702d66509e8b499dabee6252c 578 SMART SM00387 486 577 2.5E-10 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS39620 f1832fa702d66509e8b499dabee6252c 578 Pfam PF13185 GAF domain 57 196 1.3E-17 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS39620 f1832fa702d66509e8b499dabee6252c 578 Pfam PF13185 GAF domain 226 363 6.2E-10 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS39620 f1832fa702d66509e8b499dabee6252c 578 Pfam PF13581 Histidine kinase-like ATPase domain 483 547 1.6E-6 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS39620 f1832fa702d66509e8b499dabee6252c 578 SUPERFAMILY SSF55781 207 389 4.36E-21 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS39620 f1832fa702d66509e8b499dabee6252c 578 SUPERFAMILY SSF55781 40 223 1.1E-39 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS39620 f1832fa702d66509e8b499dabee6252c 578 Gene3D G3DSA:3.30.450.40 24 209 3.4E-35 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS39620 f1832fa702d66509e8b499dabee6252c 578 Gene3D G3DSA:3.30.565.10 450 577 1.2E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS39620 f1832fa702d66509e8b499dabee6252c 578 SUPERFAMILY SSF55874 483 576 3.67E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS39620 f1832fa702d66509e8b499dabee6252c 578 SMART SM00065 226 372 1.4E-4 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS39620 f1832fa702d66509e8b499dabee6252c 578 SMART SM00065 58 205 6.2E-21 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS39620 f1832fa702d66509e8b499dabee6252c 578 Pfam PF07730 Histidine kinase 380 443 7.7E-12 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMALA_RS00825 5336c183c5d2f1994b974176b3d9d7d4 325 Gene3D G3DSA:3.40.50.720 2 116 6.1E-28 T 29-03-2018 SMALA_RS00825 5336c183c5d2f1994b974176b3d9d7d4 325 Gene3D G3DSA:3.40.50.720 117 291 1.3E-51 T 29-03-2018 SMALA_RS00825 5336c183c5d2f1994b974176b3d9d7d4 325 SUPERFAMILY SSF52283 1 127 1.36E-23 T 29-03-2018 SMALA_RS00825 5336c183c5d2f1994b974176b3d9d7d4 325 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 114 288 1.5E-52 T 29-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 SMALA_RS00825 5336c183c5d2f1994b974176b3d9d7d4 325 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 34 315 7.5E-12 T 29-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 SMALA_RS00825 5336c183c5d2f1994b974176b3d9d7d4 325 SUPERFAMILY SSF51735 108 288 1.38E-51 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS24120 8695b7d097e382142f163b88412bcf43 134 SUPERFAMILY SSF54593 14 133 3.03E-20 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS24120 8695b7d097e382142f163b88412bcf43 134 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 14 128 3.6E-8 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMALA_RS24120 8695b7d097e382142f163b88412bcf43 134 Gene3D G3DSA:3.10.180.10 1 133 1.3E-19 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS06095 449fc415b9681042fe2d8d164fab969c 1040 Pfam PF00754 F5/8 type C domain 941 1029 5.9E-7 T 29-03-2018 IPR000421 Coagulation factor 5/8 C-terminal domain SMALA_RS06095 449fc415b9681042fe2d8d164fab969c 1040 Pfam PF00754 F5/8 type C domain 637 716 2.2E-17 T 29-03-2018 IPR000421 Coagulation factor 5/8 C-terminal domain SMALA_RS06095 449fc415b9681042fe2d8d164fab969c 1040 Gene3D G3DSA:2.60.120.260 514 624 2.5E-4 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS06095 449fc415b9681042fe2d8d164fab969c 1040 Gene3D G3DSA:2.60.120.260 625 739 3.6E-23 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS06095 449fc415b9681042fe2d8d164fab969c 1040 SUPERFAMILY SSF49785 633 721 1.63E-16 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS06095 449fc415b9681042fe2d8d164fab969c 1040 Gene3D G3DSA:2.60.120.260 921 1040 3.9E-9 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS06095 449fc415b9681042fe2d8d164fab969c 1040 SUPERFAMILY SSF49785 920 1029 2.13E-6 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS33740 245afa33b69e62b67cdfd6e657d3133a 507 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 65 79 1.8E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS33740 245afa33b69e62b67cdfd6e657d3133a 507 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 79 95 1.8E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS33740 245afa33b69e62b67cdfd6e657d3133a 507 Pfam PF00392 Bacterial regulatory proteins, gntR family 43 102 1.1E-12 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS33740 245afa33b69e62b67cdfd6e657d3133a 507 SMART SM00345 46 105 3.0E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS33740 245afa33b69e62b67cdfd6e657d3133a 507 Gene3D G3DSA:3.40.640.10 153 371 9.7E-39 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS33740 245afa33b69e62b67cdfd6e657d3133a 507 Gene3D G3DSA:1.10.10.10 30 106 4.2E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS33740 245afa33b69e62b67cdfd6e657d3133a 507 Pfam PF00155 Aminotransferase class I and II 159 476 7.7E-30 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMALA_RS33740 245afa33b69e62b67cdfd6e657d3133a 507 SUPERFAMILY SSF53383 126 487 5.77E-76 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS33740 245afa33b69e62b67cdfd6e657d3133a 507 Gene3D G3DSA:3.90.1150.10 372 492 4.0E-20 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS33740 245afa33b69e62b67cdfd6e657d3133a 507 SUPERFAMILY SSF46785 38 109 5.29E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS35980 5618949e34c4bc118c2ddb83cc0682bd 2093 SUPERFAMILY SSF101173 2 33 9.29E-5 T 29-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 SMALA_RS35980 5618949e34c4bc118c2ddb83cc0682bd 2093 Pfam PF08990 Erythronolide synthase docking 3 26 1.5E-11 T 29-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 SMALA_RS35980 5618949e34c4bc118c2ddb83cc0682bd 2093 SUPERFAMILY SSF47336 1716 1806 4.48E-20 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS35980 5618949e34c4bc118c2ddb83cc0682bd 2093 SUPERFAMILY SSF51735 1231 1418 1.18E-36 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS35980 5618949e34c4bc118c2ddb83cc0682bd 2093 Gene3D G3DSA:3.40.50.720 1424 1678 2.1E-48 T 29-03-2018 SMALA_RS35980 5618949e34c4bc118c2ddb83cc0682bd 2093 SMART SM00824 Thioesterase 1872 2085 9.5E-111 T 29-03-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 SMALA_RS35980 5618949e34c4bc118c2ddb83cc0682bd 2093 Pfam PF08659 KR domain 1432 1610 3.8E-59 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS35980 5618949e34c4bc118c2ddb83cc0682bd 2093 SUPERFAMILY SSF55048 694 754 6.28E-7 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS35980 5618949e34c4bc118c2ddb83cc0682bd 2093 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1745 1760 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS35980 5618949e34c4bc118c2ddb83cc0682bd 2093 Pfam PF00975 Thioesterase domain 1872 2084 1.0E-17 T 29-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 SMALA_RS35980 5618949e34c4bc118c2ddb83cc0682bd 2093 SUPERFAMILY SSF53474 1748 1786 4.39E-39 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS35980 5618949e34c4bc118c2ddb83cc0682bd 2093 SUPERFAMILY SSF53474 1847 2087 4.39E-39 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS35980 5618949e34c4bc118c2ddb83cc0682bd 2093 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 196 212 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS35980 5618949e34c4bc118c2ddb83cc0682bd 2093 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 291 408 3.8E-44 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS35980 5618949e34c4bc118c2ddb83cc0682bd 2093 Gene3D G3DSA:3.10.129.10 932 1060 4.2E-10 T 29-03-2018 SMALA_RS35980 5618949e34c4bc118c2ddb83cc0682bd 2093 SMART SM00823 Phosphopantetheine attachment site 1718 1790 5.5E-31 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS35980 5618949e34c4bc118c2ddb83cc0682bd 2093 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 567 863 2.0E-112 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS35980 5618949e34c4bc118c2ddb83cc0682bd 2093 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 411 535 2.2E-16 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS35980 5618949e34c4bc118c2ddb83cc0682bd 2093 SMART SM00825 Beta-ketoacyl synthase 35 463 1.3E-235 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS35980 5618949e34c4bc118c2ddb83cc0682bd 2093 Gene3D G3DSA:3.40.50.1820 1820 2093 5.2E-28 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS35980 5618949e34c4bc118c2ddb83cc0682bd 2093 Pfam PF14765 Polyketide synthase dehydratase 930 1222 6.3E-58 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS35980 5618949e34c4bc118c2ddb83cc0682bd 2093 SUPERFAMILY SSF51735 1431 1629 1.79E-45 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS35980 5618949e34c4bc118c2ddb83cc0682bd 2093 Gene3D G3DSA:1.10.1200.10 1711 1819 3.2E-23 T 29-03-2018 SMALA_RS35980 5618949e34c4bc118c2ddb83cc0682bd 2093 SMART SM01294 1719 1786 3.1E-4 T 29-03-2018 SMALA_RS35980 5618949e34c4bc118c2ddb83cc0682bd 2093 Gene3D G3DSA:3.40.47.10 25 295 1.5E-90 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS35980 5618949e34c4bc118c2ddb83cc0682bd 2093 SUPERFAMILY SSF53901 29 406 6.16E-108 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS35980 5618949e34c4bc118c2ddb83cc0682bd 2093 Gene3D G3DSA:3.40.366.10 743 871 3.7E-27 T 29-03-2018 SMALA_RS35980 5618949e34c4bc118c2ddb83cc0682bd 2093 Gene3D G3DSA:3.40.366.10 550 742 1.6E-50 T 29-03-2018 SMALA_RS35980 5618949e34c4bc118c2ddb83cc0682bd 2093 SMART SM00826 930 1107 2.6E-86 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS35980 5618949e34c4bc118c2ddb83cc0682bd 2093 Gene3D G3DSA:3.40.47.10 298 461 2.1E-65 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS35980 5618949e34c4bc118c2ddb83cc0682bd 2093 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1432 1612 3.6E-62 T 29-03-2018 SMALA_RS35980 5618949e34c4bc118c2ddb83cc0682bd 2093 Pfam PF00550 Phosphopantetheine attachment site 1720 1786 1.3E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS35980 5618949e34c4bc118c2ddb83cc0682bd 2093 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 33 283 8.4E-95 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS35980 5618949e34c4bc118c2ddb83cc0682bd 2093 Pfam PF00698 Acyl transferase domain 566 880 3.4E-53 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS35980 5618949e34c4bc118c2ddb83cc0682bd 2093 SUPERFAMILY SSF52151 564 689 1.26E-72 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS35980 5618949e34c4bc118c2ddb83cc0682bd 2093 SUPERFAMILY SSF52151 748 854 1.26E-72 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS33085 a89ed55a544ddcd36c1685ceba8ab374 326 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 3 310 1.8E-91 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 SMALA_RS33085 a89ed55a544ddcd36c1685ceba8ab374 326 Gene3D G3DSA:3.40.50.1370 1 169 1.7E-61 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SMALA_RS33085 a89ed55a544ddcd36c1685ceba8ab374 326 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 3 147 1.3E-42 T 29-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 SMALA_RS33085 a89ed55a544ddcd36c1685ceba8ab374 326 PRINTS PR00101 Aspartate carbamoyltransferase signature 291 305 1.0E-30 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 SMALA_RS33085 a89ed55a544ddcd36c1685ceba8ab374 326 PRINTS PR00101 Aspartate carbamoyltransferase signature 267 272 1.0E-30 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 SMALA_RS33085 a89ed55a544ddcd36c1685ceba8ab374 326 PRINTS PR00101 Aspartate carbamoyltransferase signature 226 235 1.0E-30 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 SMALA_RS33085 a89ed55a544ddcd36c1685ceba8ab374 326 PRINTS PR00101 Aspartate carbamoyltransferase signature 39 61 1.0E-30 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 SMALA_RS33085 a89ed55a544ddcd36c1685ceba8ab374 326 PRINTS PR00101 Aspartate carbamoyltransferase signature 77 86 1.0E-30 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 SMALA_RS33085 a89ed55a544ddcd36c1685ceba8ab374 326 PRINTS PR00101 Aspartate carbamoyltransferase signature 134 151 1.0E-30 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 SMALA_RS33085 a89ed55a544ddcd36c1685ceba8ab374 326 SUPERFAMILY SSF53671 2 312 1.1E-92 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SMALA_RS33085 a89ed55a544ddcd36c1685ceba8ab374 326 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 2 312 41.415 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 SMALA_RS33085 a89ed55a544ddcd36c1685ceba8ab374 326 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 263 272 2.4E-19 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SMALA_RS33085 a89ed55a544ddcd36c1685ceba8ab374 326 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 275 298 2.4E-19 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SMALA_RS33085 a89ed55a544ddcd36c1685ceba8ab374 326 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 49 68 2.4E-19 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SMALA_RS33085 a89ed55a544ddcd36c1685ceba8ab374 326 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 135 146 2.4E-19 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SMALA_RS33085 a89ed55a544ddcd36c1685ceba8ab374 326 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 49 56 - T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SMALA_RS33085 a89ed55a544ddcd36c1685ceba8ab374 326 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 163 309 7.7E-23 T 29-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 SMALA_RS33085 a89ed55a544ddcd36c1685ceba8ab374 326 Gene3D G3DSA:3.40.50.1370 170 312 2.0E-44 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SMALA_RS05210 576e8f7d3edbaf8d84b988c02c509195 461 SUPERFAMILY SSF51445 179 434 2.02E-20 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS05210 576e8f7d3edbaf8d84b988c02c509195 461 Gene3D G3DSA:3.20.20.80 174 456 2.2E-27 T 29-03-2018 SMALA_RS05210 576e8f7d3edbaf8d84b988c02c509195 461 Pfam PF00652 Ricin-type beta-trefoil lectin domain 39 160 1.8E-31 T 29-03-2018 IPR000772 Ricin B, lectin domain SMALA_RS05210 576e8f7d3edbaf8d84b988c02c509195 461 Gene3D G3DSA:2.80.10.50 81 121 1.0E-14 T 29-03-2018 SMALA_RS05210 576e8f7d3edbaf8d84b988c02c509195 461 SMART SM00458 39 163 1.1E-34 T 29-03-2018 IPR000772 Ricin B, lectin domain SMALA_RS05210 576e8f7d3edbaf8d84b988c02c509195 461 Gene3D G3DSA:2.80.10.50 122 171 8.7E-15 T 29-03-2018 SMALA_RS05210 576e8f7d3edbaf8d84b988c02c509195 461 Gene3D G3DSA:2.80.10.50 25 80 1.3E-17 T 29-03-2018 SMALA_RS05210 576e8f7d3edbaf8d84b988c02c509195 461 SUPERFAMILY SSF50370 39 161 2.55E-41 T 29-03-2018 IPR000772 Ricin B, lectin domain SMALA_RS05210 576e8f7d3edbaf8d84b988c02c509195 461 Pfam PF00704 Glycosyl hydrolases family 18 235 357 1.3E-7 T 29-03-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 SMALA_RS12890 d230d90b68e920083c54a38339fd8935 355 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 24 146 2.7E-15 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 SMALA_RS12890 d230d90b68e920083c54a38339fd8935 355 Gene3D G3DSA:3.40.50.300 70 202 1.6E-14 T 29-03-2018 SMALA_RS12890 d230d90b68e920083c54a38339fd8935 355 SUPERFAMILY SSF52540 23 173 1.03E-35 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS12890 d230d90b68e920083c54a38339fd8935 355 SUPERFAMILY SSF52540 214 267 1.03E-35 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS12890 d230d90b68e920083c54a38339fd8935 355 Gene3D G3DSA:3.40.50.300 8 69 1.4E-16 T 29-03-2018 SMALA_RS12890 d230d90b68e920083c54a38339fd8935 355 Hamap MF_00367 GTPase Era [era]. 17 355 32.789 T 29-03-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS12890 d230d90b68e920083c54a38339fd8935 355 Pfam PF07650 KH domain 262 344 1.5E-15 T 29-03-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMALA_RS12890 d230d90b68e920083c54a38339fd8935 355 Pfam PF01926 50S ribosome-binding GTPase 22 123 1.3E-19 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 SMALA_RS12890 d230d90b68e920083c54a38339fd8935 355 Gene3D G3DSA:3.30.300.20 239 355 2.3E-41 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta SMALA_RS12890 d230d90b68e920083c54a38339fd8935 355 SUPERFAMILY SSF54814 236 355 3.07E-34 T 29-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 SMALA_RS36185 f6f7f4aab223ed1569b292414a7e0c95 262 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 113 1.1E-24 T 29-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 SMALA_RS36185 f6f7f4aab223ed1569b292414a7e0c95 262 SUPERFAMILY SSF57716 211 258 2.65E-9 T 29-03-2018 SMALA_RS36185 f6f7f4aab223ed1569b292414a7e0c95 262 SUPERFAMILY SSF81624 2 137 2.09E-25 T 29-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 SMALA_RS36185 f6f7f4aab223ed1569b292414a7e0c95 262 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 142 214 1.1E-17 T 29-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 SMALA_RS36185 f6f7f4aab223ed1569b292414a7e0c95 262 SMART SM00898 2 117 3.3E-24 T 29-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 SMALA_RS36185 f6f7f4aab223ed1569b292414a7e0c95 262 SUPERFAMILY SSF46946 132 214 1.31E-21 T 29-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 SMALA_RS36185 f6f7f4aab223ed1569b292414a7e0c95 262 SMART SM01232 132 221 1.2E-27 T 29-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 SMALA_RS36185 f6f7f4aab223ed1569b292414a7e0c95 262 Gene3D G3DSA:3.20.190.10 1 126 1.2E-30 T 29-03-2018 SMALA_RS36185 f6f7f4aab223ed1569b292414a7e0c95 262 Pfam PF06827 Zinc finger found in FPG and IleRS 234 258 1.2E-5 T 29-03-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 SMALA_RS36185 f6f7f4aab223ed1569b292414a7e0c95 262 ProSitePatterns PS01242 Zinc finger FPG-type signature. 234 258 - T 29-03-2018 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 SMALA_RS36185 f6f7f4aab223ed1569b292414a7e0c95 262 Gene3D G3DSA:1.10.8.50 127 259 7.2E-34 T 29-03-2018 SMALA_RS05360 604d7f71c19489e3a35990cf02afd45f 323 SUPERFAMILY SSF49899 50 319 7.19E-42 T 29-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain SMALA_RS05360 604d7f71c19489e3a35990cf02afd45f 323 Gene3D G3DSA:2.60.120.200 48 320 1.3E-49 T 29-03-2018 SMALA_RS05360 604d7f71c19489e3a35990cf02afd45f 323 Pfam PF00722 Glycosyl hydrolases family 16 103 316 1.2E-9 T 29-03-2018 IPR000757 Glycoside hydrolase family 16 GO:0004553|GO:0005975 SMALA_RS24085 42a3931d783051d4c7d1c563e1304386 325 Gene3D G3DSA:3.40.1580.10 152 304 1.4E-18 T 29-03-2018 SMALA_RS24085 42a3931d783051d4c7d1c563e1304386 325 Pfam PF14414 A nuclease of the HNH/ENDO VII superfamily with conserved WHH 96 133 1.0E-13 T 29-03-2018 IPR032869 WHH domain-containing protein SMALA_RS24085 42a3931d783051d4c7d1c563e1304386 325 SMART SM00860 160 297 9.9E-6 T 29-03-2018 IPR018958 Knr4/Smi1-like domain SMALA_RS24085 42a3931d783051d4c7d1c563e1304386 325 SUPERFAMILY SSF160631 150 298 1.05E-15 T 29-03-2018 SMALA_RS24085 42a3931d783051d4c7d1c563e1304386 325 Pfam PF09346 SMI1 / KNR4 family (SUKH-1) 161 296 2.0E-8 T 29-03-2018 IPR018958 Knr4/Smi1-like domain SMALA_RS40295 2c6e7344b0be9705359c9a5496f934e3 160 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 46 156 9.2E-26 T 29-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS40295 2c6e7344b0be9705359c9a5496f934e3 160 SUPERFAMILY SSF56770 33 157 6.8E-47 T 29-03-2018 SMALA_RS40295 2c6e7344b0be9705359c9a5496f934e3 160 Gene3D G3DSA:3.40.50.700 49 160 2.1E-25 T 29-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS25495 813c5ff5f77ca0e9941f89b2c88830cb 408 Gene3D G3DSA:1.20.1250.20 222 408 6.8E-17 T 29-03-2018 SMALA_RS25495 813c5ff5f77ca0e9941f89b2c88830cb 408 SUPERFAMILY SSF103473 3 404 3.53E-42 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS25495 813c5ff5f77ca0e9941f89b2c88830cb 408 Pfam PF07690 Major Facilitator Superfamily 234 402 1.4E-13 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS25495 813c5ff5f77ca0e9941f89b2c88830cb 408 Pfam PF07690 Major Facilitator Superfamily 9 233 2.7E-16 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS25495 813c5ff5f77ca0e9941f89b2c88830cb 408 Gene3D G3DSA:1.20.1250.20 1 198 4.5E-17 T 29-03-2018 SMALA_RS08825 6d395e9c03dac74d35959e1bd29c9e46 220 Hamap MF_00527 Putative 3-methyladenine DNA glycosylase. 12 201 34.549 T 29-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 SMALA_RS08825 6d395e9c03dac74d35959e1bd29c9e46 220 SUPERFAMILY SSF50486 8 206 1.26E-61 T 29-03-2018 IPR011034 Formyl transferase, C-terminal-like GO:0003824 SMALA_RS08825 6d395e9c03dac74d35959e1bd29c9e46 220 Gene3D G3DSA:3.10.300.10 6 209 5.0E-76 T 29-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 SMALA_RS08825 6d395e9c03dac74d35959e1bd29c9e46 220 Pfam PF02245 Methylpurine-DNA glycosylase (MPG) 13 198 6.0E-66 T 29-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 SMALA_RS08825 6d395e9c03dac74d35959e1bd29c9e46 220 TIGRFAM TIGR00567 3mg: DNA-3-methyladenine glycosylase 10 201 9.5E-51 T 29-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 SMALA_RS15180 fac649a9c75bb33ea342809dbf6585b9 373 Pfam PF03601 Conserved hypothetical protein 698 278 353 1.2E-9 T 29-03-2018 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 SMALA_RS15180 fac649a9c75bb33ea342809dbf6585b9 373 Pfam PF03601 Conserved hypothetical protein 698 26 253 1.1E-50 T 29-03-2018 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 SMALA_RS15310 14df48fd49dcf70c0d6fbe828a6c377c 726 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 565 573 - T 29-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 SMALA_RS15310 14df48fd49dcf70c0d6fbe828a6c377c 726 SUPERFAMILY SSF47741 610 680 1.3E-26 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 SMALA_RS15310 14df48fd49dcf70c0d6fbe828a6c377c 726 Gene3D G3DSA:1.10.150.120 601 708 1.3E-31 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 SMALA_RS15310 14df48fd49dcf70c0d6fbe828a6c377c 726 Pfam PF01799 [2Fe-2S] binding domain 599 671 1.5E-23 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 SMALA_RS15310 14df48fd49dcf70c0d6fbe828a6c377c 726 SUPERFAMILY SSF54292 531 613 1.57E-18 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SMALA_RS15310 14df48fd49dcf70c0d6fbe828a6c377c 726 Gene3D G3DSA:3.10.20.30 525 600 2.6E-20 T 29-03-2018 IPR012675 Beta-grasp domain SMALA_RS35070 4ae36e025769d6fab7745e08b21d21bf 504 SUPERFAMILY SSF142019 29 231 2.88E-37 T 29-03-2018 SMALA_RS35070 4ae36e025769d6fab7745e08b21d21bf 504 SMART SM00928 312 356 1.8E-4 T 29-03-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS35070 4ae36e025769d6fab7745e08b21d21bf 504 SUPERFAMILY SSF140490 308 405 2.35E-17 T 29-03-2018 SMALA_RS35070 4ae36e025769d6fab7745e08b21d21bf 504 SUPERFAMILY SSF142984 238 303 8.37E-6 T 29-03-2018 SMALA_RS35070 4ae36e025769d6fab7745e08b21d21bf 504 Pfam PF13459 4Fe-4S single cluster domain 445 502 1.0E-8 T 29-03-2018 SMALA_RS35070 4ae36e025769d6fab7745e08b21d21bf 504 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 316 396 7.4E-18 T 29-03-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS35070 4ae36e025769d6fab7745e08b21d21bf 504 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 52 209 5.2E-28 T 29-03-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS35070 4ae36e025769d6fab7745e08b21d21bf 504 SUPERFAMILY SSF54862 443 502 9.21E-7 T 29-03-2018 SMALA_RS17435 262f9e17f58c46020c66c15fa9516049 227 Gene3D G3DSA:1.10.472.50 39 132 5.8E-15 T 29-03-2018 SMALA_RS17435 262f9e17f58c46020c66c15fa9516049 227 PIRSF PIRSF035170 7 227 2.1E-68 T 29-03-2018 IPR009218 Predicted HD phosphohydrolase SMALA_RS17435 262f9e17f58c46020c66c15fa9516049 227 SUPERFAMILY SSF109604 40 215 6.28E-28 T 29-03-2018 SMALA_RS29115 a37e6ce295b90a1fa1a7a2ed1fa183b8 251 SMART SM00895 87 224 8.2E-19 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS29115 a37e6ce295b90a1fa1a7a2ed1fa183b8 251 SUPERFAMILY SSF48008 84 228 6.02E-22 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS29115 a37e6ce295b90a1fa1a7a2ed1fa183b8 251 SUPERFAMILY SSF46785 17 81 8.52E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS29115 a37e6ce295b90a1fa1a7a2ed1fa183b8 251 Pfam PF00392 Bacterial regulatory proteins, gntR family 18 77 1.4E-17 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS29115 a37e6ce295b90a1fa1a7a2ed1fa183b8 251 Gene3D G3DSA:1.10.10.10 5 79 4.4E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS29115 a37e6ce295b90a1fa1a7a2ed1fa183b8 251 Gene3D G3DSA:1.20.120.530 80 241 1.3E-32 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS29115 a37e6ce295b90a1fa1a7a2ed1fa183b8 251 SMART SM00345 19 77 8.4E-20 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS29115 a37e6ce295b90a1fa1a7a2ed1fa183b8 251 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 37 51 1.2E-6 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS29115 a37e6ce295b90a1fa1a7a2ed1fa183b8 251 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 51 67 1.2E-6 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS29115 a37e6ce295b90a1fa1a7a2ed1fa183b8 251 Pfam PF07729 FCD domain 87 223 1.3E-24 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS14605 566b73b6b8d71e456c2db3d92232fa1a 307 SMART SM00062 62 294 8.4E-37 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SMALA_RS14605 566b73b6b8d71e456c2db3d92232fa1a 307 TIGRFAM TIGR02995 ectoine_ehuB: ectoine/hydroxyectoine ABC transporter solute-binding protein EhuB 42 306 4.1E-82 T 29-03-2018 IPR014337 Ectoine/Hydroxyectoine ABC transporter, substrate-binding protein EhuB GO:0033294|GO:0051470 SMALA_RS14605 566b73b6b8d71e456c2db3d92232fa1a 307 SUPERFAMILY SSF53850 59 291 2.51E-43 T 29-03-2018 SMALA_RS14605 566b73b6b8d71e456c2db3d92232fa1a 307 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 63 288 1.5E-42 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SMALA_RS14605 566b73b6b8d71e456c2db3d92232fa1a 307 Gene3D G3DSA:3.40.190.10 163 246 3.5E-13 T 29-03-2018 SMALA_RS14605 566b73b6b8d71e456c2db3d92232fa1a 307 Gene3D G3DSA:3.40.190.10 52 162 1.8E-23 T 29-03-2018 SMALA_RS40310 57d0282974d28a2fa1373aa056010dc4 230 ProDom PD037531 MEMBRANE HYDROGENASE SUBUNIT COMPONENT HYDROGENASE-4 E OXIDOREDUCTASE PRECURSOR SIGNAL 1.-.-.- 17 205 2.0E-24 T 29-03-2018 SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 Gene3D G3DSA:1.10.1200.10 541 621 6.3E-22 T 29-03-2018 SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 SUPERFAMILY SSF56801 2566 3125 1.83E-148 T 29-03-2018 SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 SUPERFAMILY SSF52777 1849 2107 1.78E-41 T 29-03-2018 SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 Gene3D G3DSA:3.40.50.980 2598 2727 8.0E-32 T 29-03-2018 SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 Gene3D G3DSA:3.40.50.980 5634 5748 4.5E-32 T 29-03-2018 SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 Gene3D G3DSA:2.30.38.10 1396 1479 4.9E-25 T 29-03-2018 SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 SUPERFAMILY SSF52777 3846 4092 4.34E-58 T 29-03-2018 SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 Gene3D G3DSA:1.10.1220.10 2355 2410 0.51 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1619 1634 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 SUPERFAMILY SSF56801 1047 1608 6.67E-152 T 29-03-2018 SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 Pfam PF13193 AMP-binding enzyme C-terminal domain 432 508 1.4E-12 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 Pfam PF13193 AMP-binding enzyme C-terminal domain 4533 4608 6.1E-12 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 Pfam PF13193 AMP-binding enzyme C-terminal domain 3011 3086 4.9E-11 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 Pfam PF13193 AMP-binding enzyme C-terminal domain 6031 6107 1.6E-13 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 Pfam PF13193 AMP-binding enzyme C-terminal domain 1494 1568 4.8E-14 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 ProSitePatterns PS00012 Phosphopantetheine attachment site. 6159 6174 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 SMART SM00823 Phosphopantetheine attachment site 1595 1663 2.9E-4 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 SMART SM00823 Phosphopantetheine attachment site 3113 3181 4.2E-4 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 SMART SM00823 Phosphopantetheine attachment site 6135 6204 0.0054 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 SMART SM00823 Phosphopantetheine attachment site 535 604 0.002 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 SMART SM00823 Phosphopantetheine attachment site 4634 4702 0.01 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 SUPERFAMILY SSF47336 1588 1658 9.42E-18 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 Pfam PF00668 Condensation domain 624 1067 1.1E-97 T 29-03-2018 IPR001242 Condensation domain SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 Pfam PF00668 Condensation domain 4715 5158 1.6E-71 T 29-03-2018 IPR001242 Condensation domain SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 Pfam PF00668 Condensation domain 1679 2109 2.1E-57 T 29-03-2018 IPR001242 Condensation domain SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 Pfam PF00668 Condensation domain 2138 2586 1.1E-74 T 29-03-2018 IPR001242 Condensation domain SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 Pfam PF00668 Condensation domain 5180 5624 1.2E-79 T 29-03-2018 IPR001242 Condensation domain SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 Pfam PF00668 Condensation domain 3662 4105 9.7E-85 T 29-03-2018 IPR001242 Condensation domain SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 Pfam PF00668 Condensation domain 3191 3633 5.3E-70 T 29-03-2018 IPR001242 Condensation domain SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 SUPERFAMILY SSF52777 2333 2595 1.61E-56 T 29-03-2018 SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 SUPERFAMILY SSF47336 528 600 1.58E-17 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 ProSitePatterns PS00455 Putative AMP-binding domain signature. 5772 5783 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 SUPERFAMILY SSF52777 3188 3370 6.0E-45 T 29-03-2018 SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 Gene3D G3DSA:3.40.50.980 34 173 6.2E-39 T 29-03-2018 SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 SUPERFAMILY SSF52777 5185 5362 3.67E-38 T 29-03-2018 SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 Pfam PF00501 AMP-binding enzyme 5644 6022 1.1E-94 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 Pfam PF00501 AMP-binding enzyme 4125 4525 1.2E-90 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 Pfam PF00501 AMP-binding enzyme 41 424 1.4E-90 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 Pfam PF00501 AMP-binding enzyme 2607 3003 5.7E-94 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 Pfam PF00501 AMP-binding enzyme 1087 1486 8.7E-91 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 SUPERFAMILY SSF52777 618 823 6.0E-48 T 29-03-2018 SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 SUPERFAMILY SSF52777 1677 1837 9.0E-40 T 29-03-2018 SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 SUPERFAMILY SSF52777 811 1051 1.05E-59 T 29-03-2018 SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 SUPERFAMILY SSF52777 4711 4891 9.12E-38 T 29-03-2018 SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 Pfam PF00550 Phosphopantetheine attachment site 4636 4697 1.4E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 Pfam PF00550 Phosphopantetheine attachment site 1597 1656 2.2E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 Pfam PF00550 Phosphopantetheine attachment site 6137 6200 4.5E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 Pfam PF00550 Phosphopantetheine attachment site 537 599 9.1E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 Pfam PF00550 Phosphopantetheine attachment site 3115 3174 7.0E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4658 4673 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 ProSitePatterns PS00455 Putative AMP-binding domain signature. 172 183 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 Gene3D G3DSA:1.10.1200.10 4640 4703 3.7E-24 T 29-03-2018 SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 Gene3D G3DSA:1.10.1200.10 3119 3180 8.9E-22 T 29-03-2018 SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 Gene3D G3DSA:3.40.50.980 174 325 1.5E-37 T 29-03-2018 SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 Gene3D G3DSA:3.30.559.10 622 813 1.5E-43 T 29-03-2018 SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 Gene3D G3DSA:3.30.559.10 2130 2339 1.5E-31 T 29-03-2018 SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 Gene3D G3DSA:3.30.559.10 1663 1846 3.1E-33 T 29-03-2018 SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 Gene3D G3DSA:3.30.559.10 4704 4901 2.3E-32 T 29-03-2018 SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 Gene3D G3DSA:3.30.559.10 3181 3383 4.6E-39 T 29-03-2018 SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 Gene3D G3DSA:3.30.559.10 5134 5381 6.1E-40 T 29-03-2018 SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 Gene3D G3DSA:3.30.559.10 3634 3865 1.3E-40 T 29-03-2018 SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 SUPERFAMILY SSF52777 3382 3631 3.67E-38 T 29-03-2018 SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 SUPERFAMILY SSF47336 3105 3175 3.53E-19 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 Gene3D G3DSA:1.10.1200.10 6141 6206 5.3E-20 T 29-03-2018 SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 Gene3D G3DSA:1.10.1200.10 1601 1662 7.9E-21 T 29-03-2018 SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 SUPERFAMILY SSF52777 5363 5631 5.56E-57 T 29-03-2018 SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 SUPERFAMILY SSF56801 5606 6148 7.72E-156 T 29-03-2018 SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 SUPERFAMILY SSF47336 6128 6201 9.55E-16 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 Gene3D G3DSA:2.30.38.10 2918 2996 1.6E-23 T 29-03-2018 SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 Gene3D G3DSA:2.30.38.10 336 417 3.3E-27 T 29-03-2018 SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2751 2762 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 SUPERFAMILY SSF56801 4084 4647 2.09E-146 T 29-03-2018 SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 SUPERFAMILY SSF56801 22 548 9.16E-151 T 29-03-2018 SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3137 3152 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 SUPERFAMILY SSF47336 4627 4696 3.14E-18 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 Gene3D G3DSA:2.30.38.10 5937 6013 5.5E-26 T 29-03-2018 SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 ProSitePatterns PS00012 Phosphopantetheine attachment site. 559 574 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 Gene3D G3DSA:3.40.50.980 1078 1240 7.3E-46 T 29-03-2018 SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 Gene3D G3DSA:3.40.50.980 4117 4280 8.4E-46 T 29-03-2018 SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 Gene3D G3DSA:3.40.50.980 4281 4426 6.0E-27 T 29-03-2018 SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 Gene3D G3DSA:3.40.50.980 1241 1392 5.8E-27 T 29-03-2018 SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 Gene3D G3DSA:3.40.50.980 2730 2917 3.1E-41 T 29-03-2018 SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 Gene3D G3DSA:3.40.50.980 5750 5936 3.1E-48 T 29-03-2018 SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 Gene3D G3DSA:3.30.300.30 4520 4639 1.2E-42 T 29-03-2018 SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 Gene3D G3DSA:3.30.300.30 6018 6140 2.2E-37 T 29-03-2018 SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 Gene3D G3DSA:3.30.300.30 2998 3118 3.6E-37 T 29-03-2018 SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 Gene3D G3DSA:3.30.300.30 419 540 8.3E-42 T 29-03-2018 SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 Gene3D G3DSA:3.30.300.30 1481 1600 3.2E-42 T 29-03-2018 SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 Gene3D G3DSA:2.30.38.10 4427 4517 1.1E-23 T 29-03-2018 SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 4146 4548 1.4E-125 T 29-03-2018 IPR010071 Amino acid adenylation domain SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2628 3027 1.6E-129 T 29-03-2018 IPR010071 Amino acid adenylation domain SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 5664 6047 1.3E-127 T 29-03-2018 IPR010071 Amino acid adenylation domain SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1108 1509 5.5E-127 T 29-03-2018 IPR010071 Amino acid adenylation domain SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 61 448 1.3E-129 T 29-03-2018 IPR010071 Amino acid adenylation domain SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 SUPERFAMILY SSF52777 4904 5146 8.67E-39 T 29-03-2018 SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 1981 2131 2.5E-31 T 29-03-2018 IPR010060 Non-ribosomal peptide synthase SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 5021 5172 7.9E-37 T 29-03-2018 IPR010060 Non-ribosomal peptide synthase SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 3504 3655 5.4E-37 T 29-03-2018 IPR010060 Non-ribosomal peptide synthase SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 SUPERFAMILY SSF52777 3668 3845 7.41E-43 T 29-03-2018 SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1235 1246 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS01355 38cd434c4bd5b4672bc59aea4c865129 6221 SUPERFAMILY SSF52777 2144 2327 2.22E-37 T 29-03-2018 SMALA_RS27770 74065d58cdb2578a5ac6e80ad1b4c587 227 Gene3D G3DSA:1.10.357.10 57 203 7.6E-13 T 29-03-2018 SMALA_RS27770 74065d58cdb2578a5ac6e80ad1b4c587 227 Gene3D G3DSA:1.10.10.60 10 56 5.4E-11 T 29-03-2018 SMALA_RS27770 74065d58cdb2578a5ac6e80ad1b4c587 227 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 61 6.1E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS27770 74065d58cdb2578a5ac6e80ad1b4c587 227 SUPERFAMILY SSF46689 11 81 2.51E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS27770 74065d58cdb2578a5ac6e80ad1b4c587 227 SUPERFAMILY SSF48498 92 200 5.12E-6 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS24360 333d651e36fbc05b2ea3080bbc7223e5 387 PIRSF PIRSF001434 1 387 3.8E-145 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 SMALA_RS24360 333d651e36fbc05b2ea3080bbc7223e5 387 SUPERFAMILY SSF53383 14 386 3.89E-120 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS24360 333d651e36fbc05b2ea3080bbc7223e5 387 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 14 386 4.2E-148 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 SMALA_RS24360 333d651e36fbc05b2ea3080bbc7223e5 387 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 199 213 - T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 SMALA_RS24360 333d651e36fbc05b2ea3080bbc7223e5 387 Gene3D G3DSA:3.90.1150.10 257 387 2.4E-48 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS24360 333d651e36fbc05b2ea3080bbc7223e5 387 Gene3D G3DSA:3.40.640.10 9 256 1.9E-61 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS37400 71db3b32a61249a8be198fbb4a9f8e1b 454 SUPERFAMILY SSF52343 319 450 8.25E-28 T 29-03-2018 SMALA_RS37400 71db3b32a61249a8be198fbb4a9f8e1b 454 PRINTS PR00409 Phthalate dioxygenase reductase family signature 420 428 6.7E-7 T 29-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 SMALA_RS37400 71db3b32a61249a8be198fbb4a9f8e1b 454 PRINTS PR00409 Phthalate dioxygenase reductase family signature 302 316 6.7E-7 T 29-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 SMALA_RS37400 71db3b32a61249a8be198fbb4a9f8e1b 454 PRINTS PR00409 Phthalate dioxygenase reductase family signature 339 358 6.7E-7 T 29-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 SMALA_RS37400 71db3b32a61249a8be198fbb4a9f8e1b 454 Pfam PF08022 FAD-binding domain 251 327 1.4E-4 T 29-03-2018 IPR013112 FAD-binding 8 GO:0016491|GO:0055114 SMALA_RS37400 71db3b32a61249a8be198fbb4a9f8e1b 454 Gene3D G3DSA:3.40.50.80 319 449 1.2E-22 T 29-03-2018 SMALA_RS37400 71db3b32a61249a8be198fbb4a9f8e1b 454 Pfam PF00175 Oxidoreductase NAD-binding domain 340 433 6.5E-11 T 29-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 SMALA_RS37400 71db3b32a61249a8be198fbb4a9f8e1b 454 Gene3D G3DSA:2.40.30.10 229 318 3.8E-16 T 29-03-2018 SMALA_RS37400 71db3b32a61249a8be198fbb4a9f8e1b 454 SUPERFAMILY SSF63380 233 328 9.85E-16 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 SMALA_RS37400 71db3b32a61249a8be198fbb4a9f8e1b 454 Pfam PF01794 Ferric reductase like transmembrane component 66 187 3.8E-14 T 29-03-2018 IPR013130 Ferric reductase transmembrane component-like domain SMALA_RS36950 182cd7c0a2b4dd8baf358ac852cda4fb 460 Pfam PF07690 Major Facilitator Superfamily 19 404 4.2E-38 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS36950 182cd7c0a2b4dd8baf358ac852cda4fb 460 Gene3D G3DSA:1.20.1250.20 7 194 9.3E-27 T 29-03-2018 SMALA_RS36950 182cd7c0a2b4dd8baf358ac852cda4fb 460 SUPERFAMILY SSF103473 247 445 3.53E-53 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS36950 182cd7c0a2b4dd8baf358ac852cda4fb 460 SUPERFAMILY SSF103473 8 195 3.53E-53 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS36950 182cd7c0a2b4dd8baf358ac852cda4fb 460 Gene3D G3DSA:1.20.1250.20 251 448 1.0E-16 T 29-03-2018 SMALA_RS02480 214431b6d7eef888a553faa663499253 249 SUPERFAMILY SSF81301 6 58 6.22E-9 T 29-03-2018 SMALA_RS02480 214431b6d7eef888a553faa663499253 249 Pfam PF01909 Nucleotidyltransferase domain 10 60 6.9E-6 T 29-03-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 SMALA_RS02480 214431b6d7eef888a553faa663499253 249 Gene3D G3DSA:3.30.460.10 8 131 1.0E-19 T 29-03-2018 SMALA_RS36200 b1cd663f8e3a5831a47aad538a41154b 553 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 256 310 - T 29-03-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMALA_RS36200 b1cd663f8e3a5831a47aad538a41154b 553 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 36 479 3.6E-145 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMALA_RS36200 b1cd663f8e3a5831a47aad538a41154b 553 Gene3D G3DSA:1.20.210.10 23 535 1.2E-195 T 29-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMALA_RS36200 b1cd663f8e3a5831a47aad538a41154b 553 PRINTS PR01165 Cytochrome c oxidase subunit I signature 254 275 3.6E-101 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMALA_RS36200 b1cd663f8e3a5831a47aad538a41154b 553 PRINTS PR01165 Cytochrome c oxidase subunit I signature 204 223 3.6E-101 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMALA_RS36200 b1cd663f8e3a5831a47aad538a41154b 553 PRINTS PR01165 Cytochrome c oxidase subunit I signature 322 343 3.6E-101 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMALA_RS36200 b1cd663f8e3a5831a47aad538a41154b 553 PRINTS PR01165 Cytochrome c oxidase subunit I signature 143 155 3.6E-101 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMALA_RS36200 b1cd663f8e3a5831a47aad538a41154b 553 PRINTS PR01165 Cytochrome c oxidase subunit I signature 100 124 3.6E-101 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMALA_RS36200 b1cd663f8e3a5831a47aad538a41154b 553 PRINTS PR01165 Cytochrome c oxidase subunit I signature 435 456 3.6E-101 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMALA_RS36200 b1cd663f8e3a5831a47aad538a41154b 553 PRINTS PR01165 Cytochrome c oxidase subunit I signature 385 404 3.6E-101 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMALA_RS36200 b1cd663f8e3a5831a47aad538a41154b 553 PRINTS PR01165 Cytochrome c oxidase subunit I signature 175 193 3.6E-101 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMALA_RS36200 b1cd663f8e3a5831a47aad538a41154b 553 PRINTS PR01165 Cytochrome c oxidase subunit I signature 26 51 3.6E-101 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMALA_RS36200 b1cd663f8e3a5831a47aad538a41154b 553 PRINTS PR01165 Cytochrome c oxidase subunit I signature 300 315 3.6E-101 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMALA_RS36200 b1cd663f8e3a5831a47aad538a41154b 553 PRINTS PR01165 Cytochrome c oxidase subunit I signature 73 96 3.6E-101 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMALA_RS36200 b1cd663f8e3a5831a47aad538a41154b 553 PRINTS PR01165 Cytochrome c oxidase subunit I signature 233 254 3.6E-101 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMALA_RS36200 b1cd663f8e3a5831a47aad538a41154b 553 PRINTS PR01165 Cytochrome c oxidase subunit I signature 357 375 3.6E-101 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMALA_RS36200 b1cd663f8e3a5831a47aad538a41154b 553 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 27 532 1.1E-213 T 29-03-2018 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005507|GO:0005886|GO:0006810|GO:0022900|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 SMALA_RS36200 b1cd663f8e3a5831a47aad538a41154b 553 SUPERFAMILY SSF81442 25 534 1.31E-175 T 29-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMALA_RS34825 14641506b9720e1e6e38f3c07ea47e99 548 Gene3D G3DSA:3.40.50.1820 84 508 4.5E-40 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS34825 14641506b9720e1e6e38f3c07ea47e99 548 Pfam PF00561 alpha/beta hydrolase fold 108 486 7.3E-31 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS34825 14641506b9720e1e6e38f3c07ea47e99 548 SUPERFAMILY SSF53474 106 161 1.82E-23 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS34825 14641506b9720e1e6e38f3c07ea47e99 548 SUPERFAMILY SSF53474 206 260 1.82E-23 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS34825 14641506b9720e1e6e38f3c07ea47e99 548 SUPERFAMILY SSF53474 407 506 1.82E-23 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS32105 0a0f3bfe4519cce2e015495ff6cd22c4 365 SUPERFAMILY SSF48576 54 364 1.24E-72 T 29-03-2018 IPR008949 Isoprenoid synthase domain SMALA_RS32105 0a0f3bfe4519cce2e015495ff6cd22c4 365 Pfam PF00348 Polyprenyl synthetase 71 298 7.6E-52 T 29-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 SMALA_RS32105 0a0f3bfe4519cce2e015495ff6cd22c4 365 Gene3D G3DSA:1.10.600.10 1 365 1.1E-91 T 29-03-2018 IPR008949 Isoprenoid synthase domain SMALA_RS32105 0a0f3bfe4519cce2e015495ff6cd22c4 365 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 110 124 - T 29-03-2018 IPR033749 Polyprenyl synthetase, conserved site SMALA_RS10465 c0cc5d87a05bb62d40509a5dea1a8976 598 Gene3D G3DSA:3.40.50.980 189 387 8.8E-37 T 29-03-2018 SMALA_RS10465 c0cc5d87a05bb62d40509a5dea1a8976 598 Gene3D G3DSA:3.40.50.980 13 188 1.4E-40 T 29-03-2018 SMALA_RS10465 c0cc5d87a05bb62d40509a5dea1a8976 598 Pfam PF00501 AMP-binding enzyme 23 466 2.3E-99 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS10465 c0cc5d87a05bb62d40509a5dea1a8976 598 ProSitePatterns PS00455 Putative AMP-binding domain signature. 183 194 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS10465 c0cc5d87a05bb62d40509a5dea1a8976 598 SUPERFAMILY SSF56801 17 288 7.72E-115 T 29-03-2018 SMALA_RS10465 c0cc5d87a05bb62d40509a5dea1a8976 598 SUPERFAMILY SSF56801 337 596 7.72E-115 T 29-03-2018 SMALA_RS10465 c0cc5d87a05bb62d40509a5dea1a8976 598 Gene3D G3DSA:2.30.38.10 388 459 2.3E-22 T 29-03-2018 SMALA_RS10465 c0cc5d87a05bb62d40509a5dea1a8976 598 Gene3D G3DSA:3.30.300.30 461 598 4.3E-16 T 29-03-2018 SMALA_RS34490 a3a009ddb1ac528363bd81e140bb19a4 356 Gene3D G3DSA:3.20.20.30 2 356 2.3E-70 T 29-03-2018 SMALA_RS34490 a3a009ddb1ac528363bd81e140bb19a4 356 Pfam PF00296 Luciferase-like monooxygenase 25 301 6.1E-43 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS34490 a3a009ddb1ac528363bd81e140bb19a4 356 SUPERFAMILY SSF51679 7 342 5.25E-68 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS34490 a3a009ddb1ac528363bd81e140bb19a4 356 TIGRFAM TIGR03858 LLM_2I7G: probable oxidoreductase, LLM family 7 341 1.1E-147 T 29-03-2018 IPR022290 Conserved hypothetical protein CHP03858, luciferase-like monooxygenase, putative SMALA_RS23945 a06b6ef55cf18a998ee10550b8acaf6f 317 PIRSF PIRSF005902 26 317 2.0E-68 T 29-03-2018 IPR001130 TatD family GO:0016788 SMALA_RS23945 a06b6ef55cf18a998ee10550b8acaf6f 317 SUPERFAMILY SSF51556 34 104 2.1E-72 T 29-03-2018 IPR032466 Metal-dependent hydrolase SMALA_RS23945 a06b6ef55cf18a998ee10550b8acaf6f 317 SUPERFAMILY SSF51556 137 316 2.1E-72 T 29-03-2018 IPR032466 Metal-dependent hydrolase SMALA_RS23945 a06b6ef55cf18a998ee10550b8acaf6f 317 Pfam PF01026 TatD related DNase 37 315 2.0E-68 T 29-03-2018 IPR001130 TatD family GO:0016788 SMALA_RS23945 a06b6ef55cf18a998ee10550b8acaf6f 317 Gene3D G3DSA:3.20.20.140 33 317 4.5E-78 T 29-03-2018 SMALA_RS16395 66aead73dc04d9e87eb08a40ddaab29d 582 SUPERFAMILY SSF55957 452 544 1.83E-13 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMALA_RS16395 66aead73dc04d9e87eb08a40ddaab29d 582 Gene3D G3DSA:3.30.310.50 453 572 4.3E-16 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMALA_RS16395 66aead73dc04d9e87eb08a40ddaab29d 582 Gene3D G3DSA:3.40.120.10 20 220 4.2E-60 T 29-03-2018 SMALA_RS16395 66aead73dc04d9e87eb08a40ddaab29d 582 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 338 444 5.9E-16 T 29-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMALA_RS16395 66aead73dc04d9e87eb08a40ddaab29d 582 Gene3D G3DSA:3.40.120.10 221 339 6.4E-27 T 29-03-2018 SMALA_RS16395 66aead73dc04d9e87eb08a40ddaab29d 582 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 155 164 - T 29-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMALA_RS16395 66aead73dc04d9e87eb08a40ddaab29d 582 SUPERFAMILY SSF53738 216 319 3.45E-21 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMALA_RS16395 66aead73dc04d9e87eb08a40ddaab29d 582 Gene3D G3DSA:3.40.120.10 340 451 3.4E-32 T 29-03-2018 SMALA_RS16395 66aead73dc04d9e87eb08a40ddaab29d 582 SUPERFAMILY SSF53738 309 450 9.03E-25 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMALA_RS16395 66aead73dc04d9e87eb08a40ddaab29d 582 SUPERFAMILY SSF53738 41 222 2.47E-40 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMALA_RS16395 66aead73dc04d9e87eb08a40ddaab29d 582 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 479 551 1.8E-6 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMALA_RS16395 66aead73dc04d9e87eb08a40ddaab29d 582 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 230 317 1.0E-23 T 29-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMALA_RS16395 66aead73dc04d9e87eb08a40ddaab29d 582 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 50 197 5.4E-38 T 29-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMALA_RS25440 07f5a4d1bdb60b820530969f4dbcba10 260 Gene3D G3DSA:3.40.50.1000 5 240 5.9E-20 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS25440 07f5a4d1bdb60b820530969f4dbcba10 260 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 159 179 1.8E-8 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMALA_RS25440 07f5a4d1bdb60b820530969f4dbcba10 260 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 111 124 1.8E-8 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMALA_RS25440 07f5a4d1bdb60b820530969f4dbcba10 260 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 141 157 1.8E-8 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMALA_RS25440 07f5a4d1bdb60b820530969f4dbcba10 260 Pfam PF00702 haloacid dehalogenase-like hydrolase 92 191 2.0E-8 T 29-03-2018 SMALA_RS25440 07f5a4d1bdb60b820530969f4dbcba10 260 SUPERFAMILY SSF56784 19 205 4.13E-27 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS25440 07f5a4d1bdb60b820530969f4dbcba10 260 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 95 194 1.7E-15 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMALA_RS40520 476263a9cd470c07f7acfc8857e57e55 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 2.8E-20 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS40520 476263a9cd470c07f7acfc8857e57e55 300 Gene3D G3DSA:1.10.10.10 1 84 5.3E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS40520 476263a9cd470c07f7acfc8857e57e55 300 Gene3D G3DSA:3.40.190.10 176 267 2.2E-20 T 29-03-2018 SMALA_RS40520 476263a9cd470c07f7acfc8857e57e55 300 Gene3D G3DSA:3.40.190.10 89 175 1.3E-18 T 29-03-2018 SMALA_RS40520 476263a9cd470c07f7acfc8857e57e55 300 Pfam PF03466 LysR substrate binding domain 89 293 2.1E-36 T 29-03-2018 IPR005119 LysR, substrate-binding SMALA_RS40520 476263a9cd470c07f7acfc8857e57e55 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 3.2E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS40520 476263a9cd470c07f7acfc8857e57e55 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 3.2E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS40520 476263a9cd470c07f7acfc8857e57e55 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 3.2E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS40520 476263a9cd470c07f7acfc8857e57e55 300 SUPERFAMILY SSF53850 91 297 4.81E-35 T 29-03-2018 SMALA_RS40520 476263a9cd470c07f7acfc8857e57e55 300 SUPERFAMILY SSF46785 3 85 1.79E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS26205 7cdd0ab6c2800b63263b783b4dfb8d98 328 Gene3D G3DSA:1.25.40.10 5 145 6.2E-13 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS26205 7cdd0ab6c2800b63263b783b4dfb8d98 328 SUPERFAMILY SSF48452 19 110 3.8E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS06390 fba3ef5515d4e7e52d511c2b034229cf 193 Gene3D G3DSA:1.10.10.60 8 39 1.0E-9 T 29-03-2018 SMALA_RS06390 fba3ef5515d4e7e52d511c2b034229cf 193 SUPERFAMILY SSF48498 100 162 2.28E-7 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS06390 fba3ef5515d4e7e52d511c2b034229cf 193 SUPERFAMILY SSF46689 13 73 1.65E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS06390 fba3ef5515d4e7e52d511c2b034229cf 193 Gene3D G3DSA:1.10.357.10 81 192 1.8E-8 T 29-03-2018 SMALA_RS06390 fba3ef5515d4e7e52d511c2b034229cf 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 61 5.1E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS06390 fba3ef5515d4e7e52d511c2b034229cf 193 Gene3D G3DSA:1.10.260.40 40 80 3.3E-10 T 29-03-2018 SMALA_RS00450 26a53863689097201690c83b6a446534 225 SUPERFAMILY SSF50475 17 191 9.64E-25 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS00450 26a53863689097201690c83b6a446534 225 Gene3D G3DSA:2.30.110.10 3 216 5.7E-46 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS00450 26a53863689097201690c83b6a446534 225 PIRSF PIRSF010372 3 218 8.2E-41 T 29-03-2018 IPR007396 Transcriptional regulator PAI 2-type SMALA_RS00450 26a53863689097201690c83b6a446534 225 Pfam PF04299 Putative FMN-binding domain 3 174 8.4E-39 T 29-03-2018 IPR007396 Transcriptional regulator PAI 2-type SMALA_RS28745 290937b297e1910697772410ec62f2f6 498 Pfam PF04055 Radical SAM superfamily 192 362 3.3E-19 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 SMALA_RS28745 290937b297e1910697772410ec62f2f6 498 Gene3D G3DSA:3.80.30.20 185 418 1.6E-36 T 29-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe SMALA_RS28745 290937b297e1910697772410ec62f2f6 498 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 181 477 1.3E-81 T 29-03-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 SMALA_RS28745 290937b297e1910697772410ec62f2f6 498 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 190 210 - T 29-03-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 SMALA_RS28745 290937b297e1910697772410ec62f2f6 498 SMART SM00729 186 404 4.3E-40 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 SMALA_RS28745 290937b297e1910697772410ec62f2f6 498 SUPERFAMILY SSF102114 175 408 2.35E-44 T 29-03-2018 SMALA_RS28745 290937b297e1910697772410ec62f2f6 498 Hamap MF_01865 Ribosomal protein S12 methylthiotransferase RimO [rimO]. 5 480 60.162 T 29-03-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 SMALA_RS28745 290937b297e1910697772410ec62f2f6 498 Pfam PF00919 Uncharacterized protein family UPF0004 7 105 3.4E-31 T 29-03-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 SMALA_RS28745 290937b297e1910697772410ec62f2f6 498 TIGRFAM TIGR01125 TIGR01125: ribosomal protein S12 methylthiotransferase RimO 7 477 5.0E-118 T 29-03-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 SMALA_RS28745 290937b297e1910697772410ec62f2f6 498 Gene3D G3DSA:2.40.50.140 419 482 6.3E-19 T 29-03-2018 SMALA_RS20920 330bc0ce8c362c0ee77bf110967143ff 262 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 21 157 2.1E-19 T 29-03-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 SMALA_RS20920 330bc0ce8c362c0ee77bf110967143ff 262 Gene3D G3DSA:1.20.120.450 4 164 1.2E-23 T 29-03-2018 SMALA_RS20920 330bc0ce8c362c0ee77bf110967143ff 262 SUPERFAMILY SSF109854 9 164 1.72E-19 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes SMALA_RS20920 330bc0ce8c362c0ee77bf110967143ff 262 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 21 233 1.6E-21 T 29-03-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type SMALA_RS41425 26b6295639bea177def8fdd1770d235f 611 PRINTS PR00419 Adrenodoxin reductase family signature 77 90 2.9E-6 T 29-03-2018 SMALA_RS41425 26b6295639bea177def8fdd1770d235f 611 PRINTS PR00419 Adrenodoxin reductase family signature 54 76 2.9E-6 T 29-03-2018 SMALA_RS41425 26b6295639bea177def8fdd1770d235f 611 SUPERFAMILY SSF51905 527 569 4.03E-38 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS41425 26b6295639bea177def8fdd1770d235f 611 SUPERFAMILY SSF51905 51 401 4.03E-38 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS41425 26b6295639bea177def8fdd1770d235f 611 Gene3D G3DSA:3.50.50.60 53 601 5.0E-35 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS41425 26b6295639bea177def8fdd1770d235f 611 Pfam PF01593 Flavin containing amine oxidoreductase 62 568 1.2E-21 T 29-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 SMALA_RS04460 f631e055e27c3f86f7fdea74e60e471c 359 Gene3D G3DSA:3.20.20.70 1 358 6.1E-131 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS04460 f631e055e27c3f86f7fdea74e60e471c 359 SUPERFAMILY SSF51395 1 347 2.23E-121 T 29-03-2018 SMALA_RS04460 f631e055e27c3f86f7fdea74e60e471c 359 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 4 341 6.3E-76 T 29-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 SMALA_RS12465 f63c8c5cc2ec1e1a581890b0878f327a 898 TIGRFAM TIGR02374 nitri_red_nirB: nitrite reductase [NAD(P)H], large subunit 33 845 0.0 T 29-03-2018 IPR012744 Nitrite reductase [NAD(P)H] large subunit, NirB GO:0008942|GO:0042128|GO:0050660|GO:0050661|GO:0055114 SMALA_RS12465 f63c8c5cc2ec1e1a581890b0878f327a 898 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 677 814 1.1E-18 T 29-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 SMALA_RS12465 f63c8c5cc2ec1e1a581890b0878f327a 898 Gene3D G3DSA:3.90.480.10 424 673 7.7E-19 T 29-03-2018 SMALA_RS12465 f63c8c5cc2ec1e1a581890b0878f327a 898 SUPERFAMILY SSF51905 175 339 7.07E-26 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS12465 f63c8c5cc2ec1e1a581890b0878f327a 898 PRINTS PR00397 Sirohaem Fe-binding site signature 681 699 1.4E-5 T 29-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 SMALA_RS12465 f63c8c5cc2ec1e1a581890b0878f327a 898 PRINTS PR00397 Sirohaem Fe-binding site signature 724 742 1.4E-5 T 29-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 SMALA_RS12465 f63c8c5cc2ec1e1a581890b0878f327a 898 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 605 666 2.0E-10 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 SMALA_RS12465 f63c8c5cc2ec1e1a581890b0878f327a 898 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 724 740 - T 29-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 SMALA_RS12465 f63c8c5cc2ec1e1a581890b0878f327a 898 SUPERFAMILY SSF55124 556 686 1.37E-22 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 SMALA_RS12465 f63c8c5cc2ec1e1a581890b0878f327a 898 Gene3D G3DSA:3.50.50.60 14 155 5.7E-16 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS12465 f63c8c5cc2ec1e1a581890b0878f327a 898 SUPERFAMILY SSF56014 678 852 2.09E-50 T 29-03-2018 SMALA_RS12465 f63c8c5cc2ec1e1a581890b0878f327a 898 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 174 192 2.7E-17 T 29-03-2018 SMALA_RS12465 f63c8c5cc2ec1e1a581890b0878f327a 898 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 288 310 2.7E-17 T 29-03-2018 SMALA_RS12465 f63c8c5cc2ec1e1a581890b0878f327a 898 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 33 52 2.7E-17 T 29-03-2018 SMALA_RS12465 f63c8c5cc2ec1e1a581890b0878f327a 898 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 129 147 2.7E-17 T 29-03-2018 SMALA_RS12465 f63c8c5cc2ec1e1a581890b0878f327a 898 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 261 277 2.7E-17 T 29-03-2018 SMALA_RS12465 f63c8c5cc2ec1e1a581890b0878f327a 898 Gene3D G3DSA:3.30.413.10 676 848 6.0E-38 T 29-03-2018 SMALA_RS12465 f63c8c5cc2ec1e1a581890b0878f327a 898 Pfam PF04324 BFD-like [2Fe-2S] binding domain 457 505 9.6E-13 T 29-03-2018 IPR007419 BFD-like [2Fe-2S]-binding domain SMALA_RS12465 f63c8c5cc2ec1e1a581890b0878f327a 898 Gene3D G3DSA:3.40.50.720 156 338 4.8E-31 T 29-03-2018 SMALA_RS12465 f63c8c5cc2ec1e1a581890b0878f327a 898 PIRSF PIRSF037149 25 880 0.0 T 29-03-2018 IPR017121 Nitrite reductase [NAD(P)H], large subunit GO:0042128 SMALA_RS12465 f63c8c5cc2ec1e1a581890b0878f327a 898 SUPERFAMILY SSF51905 32 214 1.47E-38 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS12465 f63c8c5cc2ec1e1a581890b0878f327a 898 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 32 318 6.1E-49 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS12465 f63c8c5cc2ec1e1a581890b0878f327a 898 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 303 310 7.7E-10 T 29-03-2018 SMALA_RS12465 f63c8c5cc2ec1e1a581890b0878f327a 898 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 132 141 7.7E-10 T 29-03-2018 SMALA_RS12465 f63c8c5cc2ec1e1a581890b0878f327a 898 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 174 199 7.7E-10 T 29-03-2018 SMALA_RS12465 f63c8c5cc2ec1e1a581890b0878f327a 898 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 262 276 7.7E-10 T 29-03-2018 SMALA_RS16735 73283b1cf8d7ef6f7e22c87a51f16d66 240 Pfam PF00440 Bacterial regulatory proteins, tetR family 37 78 4.3E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS16735 73283b1cf8d7ef6f7e22c87a51f16d66 240 SUPERFAMILY SSF46689 24 90 3.75E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS16735 73283b1cf8d7ef6f7e22c87a51f16d66 240 SUPERFAMILY SSF48498 99 239 2.56E-26 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS16735 73283b1cf8d7ef6f7e22c87a51f16d66 240 Gene3D G3DSA:1.10.10.60 21 89 4.1E-15 T 29-03-2018 SMALA_RS16735 73283b1cf8d7ef6f7e22c87a51f16d66 240 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 93 239 8.2E-16 T 29-03-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 SMALA_RS16735 73283b1cf8d7ef6f7e22c87a51f16d66 240 Gene3D G3DSA:1.10.357.10 90 240 6.8E-30 T 29-03-2018 SMALA_RS03975 5b3e4b859cf78ccd07e452b36c1c0b36 401 Gene3D G3DSA:3.30.9.10 169 321 6.0E-27 T 29-03-2018 SMALA_RS03975 5b3e4b859cf78ccd07e452b36c1c0b36 401 Gene3D G3DSA:3.50.50.60 7 168 1.1E-25 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS03975 5b3e4b859cf78ccd07e452b36c1c0b36 401 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 14 309 2.0E-78 T 29-03-2018 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 SMALA_RS03975 5b3e4b859cf78ccd07e452b36c1c0b36 401 SUPERFAMILY SSF51905 271 360 1.1E-40 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS03975 5b3e4b859cf78ccd07e452b36c1c0b36 401 SUPERFAMILY SSF51905 14 182 1.1E-40 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS03975 5b3e4b859cf78ccd07e452b36c1c0b36 401 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 15 37 5.0E-12 T 29-03-2018 SMALA_RS03975 5b3e4b859cf78ccd07e452b36c1c0b36 401 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 155 170 5.0E-12 T 29-03-2018 SMALA_RS03975 5b3e4b859cf78ccd07e452b36c1c0b36 401 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 274 289 5.0E-12 T 29-03-2018 SMALA_RS03975 5b3e4b859cf78ccd07e452b36c1c0b36 401 Pfam PF12831 FAD dependent oxidoreductase 15 162 5.1E-7 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS42990 e625fb369698bf52458970b8ba2717d0 211 SMART SM00860 33 157 0.0076 T 29-03-2018 IPR018958 Knr4/Smi1-like domain SMALA_RS42990 e625fb369698bf52458970b8ba2717d0 211 Gene3D G3DSA:3.40.1580.10 9 170 6.0E-19 T 29-03-2018 SMALA_RS42990 e625fb369698bf52458970b8ba2717d0 211 SUPERFAMILY SSF160631 27 158 8.89E-8 T 29-03-2018 SMALA_RS20240 53e716e40cb7feb9e4369926d918e58b 404 SUPERFAMILY SSF48452 161 234 3.76E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS20240 53e716e40cb7feb9e4369926d918e58b 404 SMART SM00530 12 68 4.7E-11 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS20240 53e716e40cb7feb9e4369926d918e58b 404 Gene3D G3DSA:1.10.260.40 3 83 2.2E-15 T 29-03-2018 SMALA_RS20240 53e716e40cb7feb9e4369926d918e58b 404 Gene3D G3DSA:1.25.40.10 155 400 2.3E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS20240 53e716e40cb7feb9e4369926d918e58b 404 SUPERFAMILY SSF47413 7 71 4.5E-14 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS20240 53e716e40cb7feb9e4369926d918e58b 404 Pfam PF13560 Helix-turn-helix domain 9 66 9.9E-12 T 29-03-2018 SMALA_RS01280 147828a92f64aa95cad465b1a4da805e 255 SUPERFAMILY SSF55781 71 251 7.19E-34 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS01280 147828a92f64aa95cad465b1a4da805e 255 SUPERFAMILY SSF46785 5 77 3.41E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS01280 147828a92f64aa95cad465b1a4da805e 255 SMART SM00346 5 95 1.5E-25 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMALA_RS01280 147828a92f64aa95cad465b1a4da805e 255 Pfam PF01614 Bacterial transcriptional regulator 125 248 2.0E-24 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal SMALA_RS01280 147828a92f64aa95cad465b1a4da805e 255 Gene3D G3DSA:1.10.10.10 1 74 4.3E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS01280 147828a92f64aa95cad465b1a4da805e 255 Gene3D G3DSA:3.30.450.40 75 255 1.5E-39 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS01280 147828a92f64aa95cad465b1a4da805e 255 Pfam PF09339 IclR helix-turn-helix domain 7 57 5.3E-16 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMALA_RS27695 4b28cbd6403d9ddef05002d65eaa392f 391 Gene3D G3DSA:2.120.10.30 50 301 3.1E-58 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like SMALA_RS27695 4b28cbd6403d9ddef05002d65eaa392f 391 Pfam PF07995 Glucose / Sorbosone dehydrogenase 75 375 1.4E-73 T 29-03-2018 IPR012938 Glucose/Sorbosone dehydrogenase SMALA_RS27695 4b28cbd6403d9ddef05002d65eaa392f 391 Gene3D G3DSA:2.120.10.30 302 389 4.2E-7 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like SMALA_RS27695 4b28cbd6403d9ddef05002d65eaa392f 391 SUPERFAMILY SSF50952 66 377 1.2E-48 T 29-03-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 SMALA_RS04480 b8f7f88b32bc96c62332d8c572fb50f5 405 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 227 370 3.4E-12 T 29-03-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 SMALA_RS04480 b8f7f88b32bc96c62332d8c572fb50f5 405 Gene3D G3DSA:3.30.420.40 136 393 7.5E-55 T 29-03-2018 SMALA_RS04480 b8f7f88b32bc96c62332d8c572fb50f5 405 Gene3D G3DSA:3.30.420.40 1 135 1.1E-15 T 29-03-2018 SMALA_RS04480 b8f7f88b32bc96c62332d8c572fb50f5 405 SUPERFAMILY SSF53067 126 142 2.46E-35 T 29-03-2018 SMALA_RS04480 b8f7f88b32bc96c62332d8c572fb50f5 405 SUPERFAMILY SSF53067 222 389 2.46E-35 T 29-03-2018 SMALA_RS09650 551111766d2721f78b646838d34f397f 641 Gene3D G3DSA:2.60.60.30 30 163 8.5E-21 T 29-03-2018 SMALA_RS09650 551111766d2721f78b646838d34f397f 641 Pfam PF02342 TerD domain 66 162 4.3E-17 T 29-03-2018 IPR003325 TerD domain GO:0006950 SMALA_RS04240 f5278a18eb566014b2055cd9c1a8b77f 539 SUPERFAMILY SSF56801 7 530 7.72E-130 T 29-03-2018 SMALA_RS04240 f5278a18eb566014b2055cd9c1a8b77f 539 Gene3D G3DSA:3.30.300.30 425 537 5.5E-26 T 29-03-2018 SMALA_RS04240 f5278a18eb566014b2055cd9c1a8b77f 539 Gene3D G3DSA:3.40.50.980 190 345 1.5E-35 T 29-03-2018 SMALA_RS04240 f5278a18eb566014b2055cd9c1a8b77f 539 Gene3D G3DSA:3.40.50.980 8 189 1.6E-40 T 29-03-2018 SMALA_RS04240 f5278a18eb566014b2055cd9c1a8b77f 539 Pfam PF13193 AMP-binding enzyme C-terminal domain 440 507 4.1E-17 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS04240 f5278a18eb566014b2055cd9c1a8b77f 539 Gene3D G3DSA:2.30.38.10 347 424 2.3E-22 T 29-03-2018 SMALA_RS04240 f5278a18eb566014b2055cd9c1a8b77f 539 ProSitePatterns PS00455 Putative AMP-binding domain signature. 184 195 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS04240 f5278a18eb566014b2055cd9c1a8b77f 539 Pfam PF00501 AMP-binding enzyme 16 430 5.8E-85 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS31000 8230bfff77d57d5f71f6764b920e73d9 175 Pfam PF07332 Putative Actinobacterial Holin-X, holin superfamily III 19 94 1.2E-7 T 29-03-2018 IPR009937 Putative Actinobacterial Holin-X, holin superfamily III SMALA_RS13925 e9edac34c62ca442c6089c1a19210682 74 SUPERFAMILY SSF55008 3 70 1.26E-15 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 SMALA_RS13925 e9edac34c62ca442c6089c1a19210682 74 PRINTS PR00944 Copper ion binding protein signature 57 70 4.6E-6 T 29-03-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 SMALA_RS13925 e9edac34c62ca442c6089c1a19210682 74 PRINTS PR00944 Copper ion binding protein signature 7 19 4.6E-6 T 29-03-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 SMALA_RS13925 e9edac34c62ca442c6089c1a19210682 74 PRINTS PR00944 Copper ion binding protein signature 19 32 4.6E-6 T 29-03-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 SMALA_RS13925 e9edac34c62ca442c6089c1a19210682 74 PRINTS PR00944 Copper ion binding protein signature 45 57 4.6E-6 T 29-03-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 SMALA_RS13925 e9edac34c62ca442c6089c1a19210682 74 Gene3D G3DSA:3.30.70.100 2 71 2.6E-17 T 29-03-2018 SMALA_RS13925 e9edac34c62ca442c6089c1a19210682 74 ProSitePatterns PS01047 Heavy-metal-associated domain. 12 42 - T 29-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 SMALA_RS13925 e9edac34c62ca442c6089c1a19210682 74 Pfam PF00403 Heavy-metal-associated domain 9 69 1.7E-14 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 SMALA_RS05865 de7871968b3a9d83d88171d1b9cf0ec9 245 Pfam PF00106 short chain dehydrogenase 10 207 3.2E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS05865 de7871968b3a9d83d88171d1b9cf0ec9 245 Gene3D G3DSA:3.40.50.720 153 244 6.2E-14 T 29-03-2018 SMALA_RS05865 de7871968b3a9d83d88171d1b9cf0ec9 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 1.8E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS05865 de7871968b3a9d83d88171d1b9cf0ec9 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 187 1.8E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS05865 de7871968b3a9d83d88171d1b9cf0ec9 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 1.8E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS05865 de7871968b3a9d83d88171d1b9cf0ec9 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 189 206 1.8E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS05865 de7871968b3a9d83d88171d1b9cf0ec9 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 1.8E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS05865 de7871968b3a9d83d88171d1b9cf0ec9 245 SUPERFAMILY SSF51735 10 239 1.05E-52 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS05865 de7871968b3a9d83d88171d1b9cf0ec9 245 Gene3D G3DSA:3.40.50.720 3 152 2.8E-35 T 29-03-2018 SMALA_RS12265 b055a3b15741f06c3425544bedf8aae2 316 Gene3D G3DSA:1.10.3720.10 34 316 4.6E-42 T 29-03-2018 SMALA_RS12265 b055a3b15741f06c3425544bedf8aae2 316 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 99 312 1.2E-6 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS12265 b055a3b15741f06c3425544bedf8aae2 316 SUPERFAMILY SSF161098 75 305 2.88E-50 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS14100 84a8eac22f2ea68792e87fed78e8102d 467 Pfam PF05576 PS-10 peptidase S37 31 467 3.5E-212 T 29-03-2018 IPR008761 Peptidase S37, tripeptidyl aminopeptidase SMALA_RS14100 84a8eac22f2ea68792e87fed78e8102d 467 Gene3D G3DSA:3.40.50.1820 50 439 7.4E-16 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS14100 84a8eac22f2ea68792e87fed78e8102d 467 SUPERFAMILY SSF53474 362 423 2.5E-11 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS14100 84a8eac22f2ea68792e87fed78e8102d 467 SUPERFAMILY SSF53474 89 213 2.5E-11 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS13930 7b2be295d473ce27ababc4968bb61c2e 785 SUPERFAMILY SSF55008 19 86 1.7E-18 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 SMALA_RS13930 7b2be295d473ce27ababc4968bb61c2e 785 Gene3D G3DSA:3.40.50.1000 600 748 2.7E-36 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS13930 7b2be295d473ce27ababc4968bb61c2e 785 Pfam PF00122 E1-E2 ATPase 288 454 2.2E-51 T 29-03-2018 SMALA_RS13930 7b2be295d473ce27ababc4968bb61c2e 785 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 179 778 2.1E-175 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 SMALA_RS13930 7b2be295d473ce27ababc4968bb61c2e 785 Gene3D G3DSA:3.30.70.100 19 90 6.7E-19 T 29-03-2018 SMALA_RS13930 7b2be295d473ce27ababc4968bb61c2e 785 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 648 664 9.8E-7 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMALA_RS13930 7b2be295d473ce27ababc4968bb61c2e 785 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 676 692 9.8E-7 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMALA_RS13930 7b2be295d473ce27ababc4968bb61c2e 785 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 707 732 9.8E-7 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMALA_RS13930 7b2be295d473ce27ababc4968bb61c2e 785 ProSitePatterns PS01047 Heavy-metal-associated domain. 28 56 - T 29-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 SMALA_RS13930 7b2be295d473ce27ababc4968bb61c2e 785 Pfam PF00702 haloacid dehalogenase-like hydrolase 472 690 1.3E-44 T 29-03-2018 SMALA_RS13930 7b2be295d473ce27ababc4968bb61c2e 785 Gene3D G3DSA:3.40.1110.10 497 599 6.7E-35 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 SMALA_RS13930 7b2be295d473ce27ababc4968bb61c2e 785 Pfam PF00403 Heavy-metal-associated domain 26 84 4.1E-13 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 SMALA_RS13930 7b2be295d473ce27ababc4968bb61c2e 785 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 290 757 1.4E-80 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMALA_RS13930 7b2be295d473ce27ababc4968bb61c2e 785 SUPERFAMILY SSF56784 474 494 1.27E-54 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS13930 7b2be295d473ce27ababc4968bb61c2e 785 SUPERFAMILY SSF56784 533 776 1.27E-54 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS13930 7b2be295d473ce27ababc4968bb61c2e 785 SUPERFAMILY SSF81665 725 745 6.8E-12 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SMALA_RS13930 7b2be295d473ce27ababc4968bb61c2e 785 SUPERFAMILY SSF81665 377 470 6.8E-12 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SMALA_RS13930 7b2be295d473ce27ababc4968bb61c2e 785 SUPERFAMILY SSF81665 229 264 6.8E-12 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SMALA_RS13930 7b2be295d473ce27ababc4968bb61c2e 785 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 676 695 2.6E-20 T 29-03-2018 SMALA_RS13930 7b2be295d473ce27ababc4968bb61c2e 785 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 476 490 2.6E-20 T 29-03-2018 SMALA_RS13930 7b2be295d473ce27ababc4968bb61c2e 785 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 326 340 2.6E-20 T 29-03-2018 SMALA_RS13930 7b2be295d473ce27ababc4968bb61c2e 785 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 623 633 2.6E-20 T 29-03-2018 SMALA_RS13930 7b2be295d473ce27ababc4968bb61c2e 785 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 699 711 2.6E-20 T 29-03-2018 SMALA_RS13930 7b2be295d473ce27ababc4968bb61c2e 785 ProSitePatterns PS01229 Hypothetical cof family signature 2. 676 698 - T 29-03-2018 SMALA_RS13930 7b2be295d473ce27ababc4968bb61c2e 785 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 478 484 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 SMALA_RS13930 7b2be295d473ce27ababc4968bb61c2e 785 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 292 779 5.4E-143 T 29-03-2018 SMALA_RS13930 7b2be295d473ce27ababc4968bb61c2e 785 Gene3D G3DSA:1.20.1110.10 118 496 1.8E-42 T 29-03-2018 SMALA_RS13930 7b2be295d473ce27ababc4968bb61c2e 785 SUPERFAMILY SSF81653 288 376 1.22E-22 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 SMALA_RS36605 c520061d53a1a042d07d94805d640b39 306 Pfam PF08443 RimK-like ATP-grasp domain 91 251 7.7E-10 T 29-03-2018 IPR013651 ATP-grasp fold, RimK-type Reactome: R-HSA-70614 SMALA_RS36605 c520061d53a1a042d07d94805d640b39 306 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 126 140 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SMALA_RS36605 c520061d53a1a042d07d94805d640b39 306 Gene3D G3DSA:3.30.470.20 163 250 4.4E-15 T 29-03-2018 SMALA_RS36605 c520061d53a1a042d07d94805d640b39 306 Gene3D G3DSA:3.30.1490.20 99 162 3.4E-12 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SMALA_RS36605 c520061d53a1a042d07d94805d640b39 306 SUPERFAMILY SSF56059 91 251 1.67E-25 T 29-03-2018 SMALA_RS36605 c520061d53a1a042d07d94805d640b39 306 Gene3D G3DSA:3.40.50.20 1 98 2.1E-10 T 29-03-2018 SMALA_RS31685 2a1ed1e3774fa7ad1f80a204e9fb2fe7 344 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 189 217 3.9E-9 T 29-03-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 SMALA_RS31685 2a1ed1e3774fa7ad1f80a204e9fb2fe7 344 SUPERFAMILY SSF48179 187 337 1.42E-34 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMALA_RS31685 2a1ed1e3774fa7ad1f80a204e9fb2fe7 344 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 7 30 8.5E-13 T 29-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 SMALA_RS31685 2a1ed1e3774fa7ad1f80a204e9fb2fe7 344 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 178 206 8.5E-13 T 29-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 SMALA_RS31685 2a1ed1e3774fa7ad1f80a204e9fb2fe7 344 TIGRFAM TIGR00872 gnd_rel: 6-phosphogluconate dehydrogenase (decarboxylating) 7 340 6.0E-120 T 29-03-2018 IPR004849 6-phosphogluconate dehydrogenase, YqeC-type GO:0055114 SMALA_RS31685 2a1ed1e3774fa7ad1f80a204e9fb2fe7 344 SUPERFAMILY SSF51735 7 166 1.31E-42 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS31685 2a1ed1e3774fa7ad1f80a204e9fb2fe7 344 Gene3D G3DSA:3.40.50.720 3 190 3.4E-35 T 29-03-2018 SMALA_RS31685 2a1ed1e3774fa7ad1f80a204e9fb2fe7 344 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 8 159 1.9E-36 T 29-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 SMALA_RS31685 2a1ed1e3774fa7ad1f80a204e9fb2fe7 344 SMART SM01350 189 313 2.4E-4 T 29-03-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 SMALA_RS31685 2a1ed1e3774fa7ad1f80a204e9fb2fe7 344 Gene3D G3DSA:1.10.1040.10 191 343 9.8E-39 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMALA_RS29390 6bfe0771bce6c9c4f8a200b5769ba287 243 SMART SM00346 1 85 0.0012 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMALA_RS29390 6bfe0771bce6c9c4f8a200b5769ba287 243 Pfam PF01614 Bacterial transcriptional regulator 120 222 6.6E-6 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal SMALA_RS29390 6bfe0771bce6c9c4f8a200b5769ba287 243 SUPERFAMILY SSF46785 2 67 2.12E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS29390 6bfe0771bce6c9c4f8a200b5769ba287 243 Pfam PF09339 IclR helix-turn-helix domain 2 49 2.7E-8 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMALA_RS29390 6bfe0771bce6c9c4f8a200b5769ba287 243 Gene3D G3DSA:3.30.450.40 68 231 3.8E-21 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS29390 6bfe0771bce6c9c4f8a200b5769ba287 243 SUPERFAMILY SSF55781 66 226 2.22E-21 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS29390 6bfe0771bce6c9c4f8a200b5769ba287 243 Gene3D G3DSA:1.10.10.10 2 55 8.3E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS42180 3398621da5b8706e372ea6d0349271c5 336 Gene3D G3DSA:1.10.10.10 175 222 5.2E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS42180 3398621da5b8706e372ea6d0349271c5 336 Gene3D G3DSA:1.10.10.10 6 49 4.7E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS42180 3398621da5b8706e372ea6d0349271c5 336 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 191 202 1.7E-7 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMALA_RS42180 3398621da5b8706e372ea6d0349271c5 336 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 175 191 1.7E-7 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMALA_RS42180 3398621da5b8706e372ea6d0349271c5 336 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 202 221 1.7E-7 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMALA_RS42180 3398621da5b8706e372ea6d0349271c5 336 Pfam PF13404 AsnC-type helix-turn-helix domain 7 46 1.3E-13 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMALA_RS42180 3398621da5b8706e372ea6d0349271c5 336 SUPERFAMILY SSF46785 6 48 1.07E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS42180 3398621da5b8706e372ea6d0349271c5 336 Pfam PF13412 Winged helix-turn-helix DNA-binding 175 220 7.3E-9 T 29-03-2018 SMALA_RS42180 3398621da5b8706e372ea6d0349271c5 336 SUPERFAMILY SSF54909 236 314 2.55E-9 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel SMALA_RS42180 3398621da5b8706e372ea6d0349271c5 336 Gene3D G3DSA:3.30.70.920 63 143 0.22 T 29-03-2018 SMALA_RS42180 3398621da5b8706e372ea6d0349271c5 336 Gene3D G3DSA:3.30.70.920 227 319 7.2E-12 T 29-03-2018 SMALA_RS42180 3398621da5b8706e372ea6d0349271c5 336 SUPERFAMILY SSF46785 175 225 8.67E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS42180 3398621da5b8706e372ea6d0349271c5 336 SMART SM00344 175 280 3.8E-6 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 SMALA_RS42180 3398621da5b8706e372ea6d0349271c5 336 Pfam PF01037 Lrp/AsnC ligand binding domain 248 310 4.7E-10 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain SMALA_RS07880 b8722439bf6900e2c2eced176c450f82 2344 SUPERFAMILY SSF52540 75 278 4.51E-22 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS07880 b8722439bf6900e2c2eced176c450f82 2344 SUPERFAMILY SSF52540 97 155 8.43E-25 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS07880 b8722439bf6900e2c2eced176c450f82 2344 SUPERFAMILY SSF52540 1086 1193 8.43E-25 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS07880 b8722439bf6900e2c2eced176c450f82 2344 Pfam PF00270 DEAD/DEAH box helicase 79 257 6.5E-15 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 SMALA_RS07880 b8722439bf6900e2c2eced176c450f82 2344 Gene3D G3DSA:3.40.50.300 674 1196 2.5E-20 T 29-03-2018 SMALA_RS07880 b8722439bf6900e2c2eced176c450f82 2344 Pfam PF00271 Helicase conserved C-terminal domain 1097 1171 6.3E-11 T 29-03-2018 IPR001650 Helicase, C-terminal SMALA_RS07880 b8722439bf6900e2c2eced176c450f82 2344 Gene3D G3DSA:3.40.50.300 66 576 1.1E-24 T 29-03-2018 SMALA_RS07880 b8722439bf6900e2c2eced176c450f82 2344 Pfam PF09369 Domain of unknown function (DUF1998) 1689 1778 3.5E-11 T 29-03-2018 IPR018973 DEAD/DEAH-box helicase, putative SMALA_RS07880 b8722439bf6900e2c2eced176c450f82 2344 Gene3D G3DSA:2.10.230.10 1473 1630 0.0075 T 29-03-2018 SMALA_RS07880 b8722439bf6900e2c2eced176c450f82 2344 Gene3D G3DSA:3.40.960.10 1876 1966 3.7E-4 T 29-03-2018 SMALA_RS07880 b8722439bf6900e2c2eced176c450f82 2344 SMART SM00487 72 307 3.1E-13 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain SMALA_RS07880 b8722439bf6900e2c2eced176c450f82 2344 SMART SM00490 1087 1172 1.1E-14 T 29-03-2018 IPR001650 Helicase, C-terminal SMALA_RS02465 a7076771a910a612edb8a103ad9ce9a9 210 Gene3D G3DSA:1.10.10.60 1 59 3.1E-16 T 29-03-2018 SMALA_RS02465 a7076771a910a612edb8a103ad9ce9a9 210 SUPERFAMILY SSF46689 10 76 7.18E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS02465 a7076771a910a612edb8a103ad9ce9a9 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 70 4.4E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS02465 a7076771a910a612edb8a103ad9ce9a9 210 Gene3D G3DSA:1.10.10.60 60 174 1.8E-8 T 29-03-2018 SMALA_RS02465 a7076771a910a612edb8a103ad9ce9a9 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 1.0E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS02465 a7076771a910a612edb8a103ad9ce9a9 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 68 1.0E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 SUPERFAMILY SSF52777 77 276 1.45E-42 T 29-03-2018 SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 Pfam PF13193 AMP-binding enzyme C-terminal domain 939 1010 9.0E-16 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 Pfam PF13193 AMP-binding enzyme C-terminal domain 3557 3628 4.7E-7 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 Pfam PF13193 AMP-binding enzyme C-terminal domain 2487 2563 5.4E-13 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 Pfam PF13193 AMP-binding enzyme C-terminal domain 4627 4703 1.1E-16 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 Gene3D G3DSA:3.40.50.980 3134 3289 2.5E-38 T 29-03-2018 SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 Gene3D G3DSA:3.40.50.980 2069 2229 2.5E-45 T 29-03-2018 SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 SUPERFAMILY SSF52777 3741 3918 1.89E-47 T 29-03-2018 SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 SUPERFAMILY SSF53474 4798 5069 1.91E-56 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4752 4767 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 Gene3D G3DSA:1.10.1200.10 2592 2652 2.5E-25 T 29-03-2018 SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 Gene3D G3DSA:1.10.1200.10 4732 4803 9.8E-24 T 29-03-2018 SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 Gene3D G3DSA:1.10.1200.10 3659 3717 2.1E-26 T 29-03-2018 SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 SUPERFAMILY SSF52777 1800 2038 1.89E-55 T 29-03-2018 SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 ProSitePatterns PS00455 Putative AMP-binding domain signature. 683 694 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 Gene3D G3DSA:3.30.559.10 1604 1817 2.9E-40 T 29-03-2018 SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 Gene3D G3DSA:3.30.559.10 3718 3943 3.3E-44 T 29-03-2018 SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 Gene3D G3DSA:3.30.559.10 2653 2871 8.6E-47 T 29-03-2018 SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 SUPERFAMILY SSF47336 2581 2653 5.63E-20 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 Gene3D G3DSA:3.40.50.980 529 678 2.7E-36 T 29-03-2018 SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 Gene3D G3DSA:2.30.38.10 3457 3539 5.8E-22 T 29-03-2018 SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 Gene3D G3DSA:2.30.38.10 2388 2469 1.1E-21 T 29-03-2018 SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 Gene3D G3DSA:2.30.38.10 4528 4609 1.0E-24 T 29-03-2018 SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 Gene3D G3DSA:3.40.50.980 4206 4368 1.7E-48 T 29-03-2018 SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 SUPERFAMILY SSF52777 3930 4200 2.78E-59 T 29-03-2018 SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 Gene3D G3DSA:3.30.300.30 3544 3658 7.7E-34 T 29-03-2018 SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 Gene3D G3DSA:3.30.300.30 2474 2591 9.8E-41 T 29-03-2018 SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 Gene3D G3DSA:3.30.300.30 4614 4731 1.3E-43 T 29-03-2018 SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 Gene3D G3DSA:3.30.300.30 926 1040 1.6E-39 T 29-03-2018 SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 SUPERFAMILY SSF56801 4172 4741 3.4E-151 T 29-03-2018 SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 SUPERFAMILY SSF47336 3648 3720 4.71E-22 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 SUPERFAMILY SSF52777 262 525 6.34E-62 T 29-03-2018 SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2225 2236 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 Gene3D G3DSA:3.30.559.10 1103 1311 6.1E-25 T 29-03-2018 SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 SUPERFAMILY SSF52777 2674 2846 1.22E-49 T 29-03-2018 SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 Gene3D G3DSA:3.40.50.980 2230 2379 6.4E-35 T 29-03-2018 SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 Gene3D G3DSA:3.40.50.980 3290 3444 1.0E-38 T 29-03-2018 SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 Pfam PF00550 Phosphopantetheine attachment site 1037 1097 9.3E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 Pfam PF00550 Phosphopantetheine attachment site 3657 3717 1.5E-16 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 Pfam PF00550 Phosphopantetheine attachment site 4730 4793 6.3E-17 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 Pfam PF00550 Phosphopantetheine attachment site 2590 2653 2.3E-15 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 SUPERFAMILY SSF47336 1028 1097 1.44E-17 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 3163 3573 3.7E-121 T 29-03-2018 IPR010071 Amino acid adenylation domain SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 558 955 6.3E-132 T 29-03-2018 IPR010071 Amino acid adenylation domain SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 4234 4643 8.7E-126 T 29-03-2018 IPR010071 Amino acid adenylation domain SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2098 2503 4.7E-127 T 29-03-2018 IPR010071 Amino acid adenylation domain SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 Gene3D G3DSA:1.10.1200.10 1041 1102 2.0E-23 T 29-03-2018 SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3679 3694 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 SMART SM00823 Phosphopantetheine attachment site 3655 3724 7.7E-11 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 SMART SM00823 Phosphopantetheine attachment site 2588 2657 3.0E-7 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 SMART SM00823 Phosphopantetheine attachment site 1035 1103 2.7E-7 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 SMART SM00823 Phosphopantetheine attachment site 4728 4797 2.3E-9 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 1444 1604 1.0E-39 T 29-03-2018 IPR010060 Non-ribosomal peptide synthase SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1059 1074 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 Gene3D G3DSA:3.40.50.980 4369 4523 7.7E-24 T 29-03-2018 SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 SUPERFAMILY SSF56801 3102 3668 1.57E-146 T 29-03-2018 SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 Gene3D G3DSA:2.30.38.10 846 924 4.1E-24 T 29-03-2018 SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 Gene3D G3DSA:3.30.559.10 69 271 3.0E-41 T 29-03-2018 SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 ProSitePatterns PS00455 Putative AMP-binding domain signature. 3285 3296 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 SMART SM00824 Thioesterase 4820 5014 0.0078 T 29-03-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2612 2627 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 Pfam PF00975 Thioesterase domain 4818 4943 7.9E-25 T 29-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 SUPERFAMILY SSF56801 496 1048 6.15E-159 T 29-03-2018 SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 Pfam PF00668 Condensation domain 1137 1502 4.0E-32 T 29-03-2018 IPR001242 Condensation domain SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 Pfam PF00668 Condensation domain 3738 4193 1.2E-85 T 29-03-2018 IPR001242 Condensation domain SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 Pfam PF00668 Condensation domain 2672 3122 7.6E-93 T 29-03-2018 IPR001242 Condensation domain SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 Pfam PF00668 Condensation domain 1614 2055 2.3E-80 T 29-03-2018 IPR001242 Condensation domain SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 Pfam PF00668 Condensation domain 79 516 1.0E-86 T 29-03-2018 IPR001242 Condensation domain SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 Pfam PF00501 AMP-binding enzyme 537 931 1.0E-96 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 Pfam PF00501 AMP-binding enzyme 4213 4619 4.9E-88 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 Pfam PF00501 AMP-binding enzyme 3142 3549 1.1E-85 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 Pfam PF00501 AMP-binding enzyme 2076 2479 3.7E-91 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 SUPERFAMILY SSF52777 1310 1581 1.56E-25 T 29-03-2018 SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 ProSitePatterns PS00455 Putative AMP-binding domain signature. 4364 4375 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 Gene3D G3DSA:3.40.50.1820 4805 5070 9.7E-28 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 SUPERFAMILY SSF52777 1612 1812 5.23E-42 T 29-03-2018 SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 SUPERFAMILY SSF52777 2858 3129 1.67E-62 T 29-03-2018 SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 Gene3D G3DSA:3.40.50.980 679 845 6.6E-42 T 29-03-2018 SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 SUPERFAMILY SSF56801 2034 2601 5.1E-149 T 29-03-2018 SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 SUPERFAMILY SSF47336 4721 4793 1.96E-20 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS40920 d9ae96d661419014ed6d57d6ce107d5e 5073 SUPERFAMILY SSF52777 1114 1319 7.0E-30 T 29-03-2018 SMALA_RS08360 3bd6d10815be23f7bcc6cd7b3dadcf0d 370 SUPERFAMILY SSF52540 177 315 4.32E-18 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS08360 3bd6d10815be23f7bcc6cd7b3dadcf0d 370 SMART SM00382 179 316 7.5E-5 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS08360 3bd6d10815be23f7bcc6cd7b3dadcf0d 370 Gene3D G3DSA:3.40.50.300 91 322 9.1E-17 T 29-03-2018 SMALA_RS08360 3bd6d10815be23f7bcc6cd7b3dadcf0d 370 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 183 313 4.8E-11 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 SMALA_RS22195 07579ba4a0345f2dde5273643f8bca89 336 Pfam PF00348 Polyprenyl synthetase 41 272 3.2E-59 T 29-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 SMALA_RS22195 07579ba4a0345f2dde5273643f8bca89 336 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 212 224 - T 29-03-2018 IPR033749 Polyprenyl synthetase, conserved site SMALA_RS22195 07579ba4a0345f2dde5273643f8bca89 336 Gene3D G3DSA:1.10.600.10 10 336 6.1E-97 T 29-03-2018 IPR008949 Isoprenoid synthase domain SMALA_RS22195 07579ba4a0345f2dde5273643f8bca89 336 SUPERFAMILY SSF48576 22 334 4.46E-83 T 29-03-2018 IPR008949 Isoprenoid synthase domain SMALA_RS41010 ca39f5887a49eded7b4cce8892ac697e 445 SUPERFAMILY SSF51703 15 412 2.82E-112 T 29-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMALA_RS41010 ca39f5887a49eded7b4cce8892ac697e 445 PIRSF PIRSF001495 1 428 4.8E-129 T 29-03-2018 IPR006396 Glutamate mutase epsilon subunit GO:0019670|GO:0050097 KEGG: 00630+5.4.99.1|KEGG: 00660+5.4.99.1|MetaCyc: PWY-5087|MetaCyc: PWY-5103|MetaCyc: PWY-6728 SMALA_RS41010 ca39f5887a49eded7b4cce8892ac697e 445 Gene3D G3DSA:3.20.20.240 2 368 2.2E-92 T 29-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMALA_RS41010 ca39f5887a49eded7b4cce8892ac697e 445 Pfam PF06368 Methylaspartate mutase E chain (MutE) 16 390 1.1E-88 T 29-03-2018 IPR006396 Glutamate mutase epsilon subunit GO:0019670|GO:0050097 KEGG: 00630+5.4.99.1|KEGG: 00660+5.4.99.1|MetaCyc: PWY-5087|MetaCyc: PWY-5103|MetaCyc: PWY-6728 SMALA_RS40965 7da20d1463f5b2ade5c4bd90d9a5c624 402 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 247 357 5.7E-33 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS40965 7da20d1463f5b2ade5c4bd90d9a5c624 402 SUPERFAMILY SSF53901 3 244 1.71E-52 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS40965 7da20d1463f5b2ade5c4bd90d9a5c624 402 SMART SM00825 Beta-ketoacyl synthase 5 401 1.6E-16 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS40965 7da20d1463f5b2ade5c4bd90d9a5c624 402 SUPERFAMILY SSF53901 209 399 4.1E-62 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS40965 7da20d1463f5b2ade5c4bd90d9a5c624 402 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 154 170 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS40965 7da20d1463f5b2ade5c4bd90d9a5c624 402 Gene3D G3DSA:3.40.47.10 1 251 3.4E-56 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS40965 7da20d1463f5b2ade5c4bd90d9a5c624 402 Gene3D G3DSA:3.40.47.10 252 400 7.0E-46 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS40965 7da20d1463f5b2ade5c4bd90d9a5c624 402 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3 239 6.0E-38 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS12325 f3f46c7e29f779e838c326e6d0dbf93f 340 Gene3D G3DSA:3.40.50.1820 58 338 2.6E-49 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS12325 f3f46c7e29f779e838c326e6d0dbf93f 340 SUPERFAMILY SSF53474 56 340 1.59E-63 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS12325 f3f46c7e29f779e838c326e6d0dbf93f 340 Pfam PF00561 alpha/beta hydrolase fold 81 184 4.1E-16 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS12325 f3f46c7e29f779e838c326e6d0dbf93f 340 PRINTS PR00412 Epoxide hydrolase signature 315 337 3.8E-8 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS12325 f3f46c7e29f779e838c326e6d0dbf93f 340 PRINTS PR00412 Epoxide hydrolase signature 86 104 3.8E-8 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS42045 7fd3f53de5e2103f471e4c1081231899 360 SUPERFAMILY SSF88697 279 340 7.18E-8 T 29-03-2018 IPR015947 PUA-like domain SMALA_RS42045 7fd3f53de5e2103f471e4c1081231899 360 Gene3D G3DSA:2.30.130.10 278 346 8.8E-10 T 29-03-2018 IPR002478 PUA domain GO:0003723 SMALA_RS42045 7fd3f53de5e2103f471e4c1081231899 360 SUPERFAMILY SSF53633 12 255 1.57E-44 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase SMALA_RS42045 7fd3f53de5e2103f471e4c1081231899 360 Pfam PF01472 PUA domain 280 338 6.5E-6 T 29-03-2018 IPR002478 PUA domain GO:0003723 SMALA_RS42045 7fd3f53de5e2103f471e4c1081231899 360 Pfam PF00696 Amino acid kinase family 11 233 2.2E-26 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase SMALA_RS42045 7fd3f53de5e2103f471e4c1081231899 360 PRINTS PR00474 Glutamate 5-kinase family signature 147 174 8.4E-31 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 SMALA_RS42045 7fd3f53de5e2103f471e4c1081231899 360 PRINTS PR00474 Glutamate 5-kinase family signature 80 108 8.4E-31 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 SMALA_RS42045 7fd3f53de5e2103f471e4c1081231899 360 PRINTS PR00474 Glutamate 5-kinase family signature 47 61 8.4E-31 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 SMALA_RS42045 7fd3f53de5e2103f471e4c1081231899 360 PRINTS PR00474 Glutamate 5-kinase family signature 208 228 8.4E-31 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 SMALA_RS42045 7fd3f53de5e2103f471e4c1081231899 360 TIGRFAM TIGR01027 proB: glutamate 5-kinase 12 338 7.1E-70 T 29-03-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 SMALA_RS42045 7fd3f53de5e2103f471e4c1081231899 360 PIRSF PIRSF000729 7 354 3.8E-72 T 29-03-2018 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 SMALA_RS42045 7fd3f53de5e2103f471e4c1081231899 360 Gene3D G3DSA:3.40.1160.10 5 255 1.1E-36 T 29-03-2018 SMALA_RS12630 f10a4db6160ed9f97ec26d83cbf5ea24 908 SUPERFAMILY SSF52009 398 524 1.57E-32 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 SMALA_RS12630 f10a4db6160ed9f97ec26d83cbf5ea24 908 TIGRFAM TIGR01828 pyru_phos_dikin: pyruvate, phosphate dikinase 8 904 0.0 T 29-03-2018 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SMALA_RS12630 f10a4db6160ed9f97ec26d83cbf5ea24 908 PIRSF PIRSF000853 7 908 0.0 T 29-03-2018 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SMALA_RS12630 f10a4db6160ed9f97ec26d83cbf5ea24 908 SUPERFAMILY SSF51621 545 904 3.14E-113 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SMALA_RS12630 f10a4db6160ed9f97ec26d83cbf5ea24 908 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 548 901 3.0E-86 T 29-03-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 SMALA_RS12630 f10a4db6160ed9f97ec26d83cbf5ea24 908 Gene3D G3DSA:3.30.470.20 248 345 6.0E-20 T 29-03-2018 SMALA_RS12630 f10a4db6160ed9f97ec26d83cbf5ea24 908 Gene3D G3DSA:3.20.20.60 562 908 1.2E-111 T 29-03-2018 SMALA_RS12630 f10a4db6160ed9f97ec26d83cbf5ea24 908 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 23 291 1.9E-42 T 29-03-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 SMALA_RS12630 f10a4db6160ed9f97ec26d83cbf5ea24 908 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 300 355 1.6E-9 T 29-03-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 SMALA_RS12630 f10a4db6160ed9f97ec26d83cbf5ea24 908 Gene3D G3DSA:1.20.80.30 122 202 5.9E-33 T 29-03-2018 SMALA_RS12630 f10a4db6160ed9f97ec26d83cbf5ea24 908 Gene3D G3DSA:3.50.30.10 398 547 4.7E-36 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 SMALA_RS12630 f10a4db6160ed9f97ec26d83cbf5ea24 908 Gene3D G3DSA:1.10.189.10 346 391 9.1E-16 T 29-03-2018 SMALA_RS12630 f10a4db6160ed9f97ec26d83cbf5ea24 908 Gene3D G3DSA:3.30.1490.20 8 121 1.0E-34 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SMALA_RS12630 f10a4db6160ed9f97ec26d83cbf5ea24 908 Pfam PF00391 PEP-utilising enzyme, mobile domain 428 515 4.0E-25 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 SMALA_RS12630 f10a4db6160ed9f97ec26d83cbf5ea24 908 SUPERFAMILY SSF56059 7 381 1.77E-133 T 29-03-2018 SMALA_RS12630 f10a4db6160ed9f97ec26d83cbf5ea24 908 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 456 467 - T 29-03-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 SMALA_RS33040 f00053b3457854c17265561c61403ae4 394 Pfam PF01264 Chorismate synthase 4 368 3.7E-117 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 SMALA_RS33040 f00053b3457854c17265561c61403ae4 394 SUPERFAMILY SSF103263 3 390 1.14E-137 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 SMALA_RS33040 f00053b3457854c17265561c61403ae4 394 Gene3D G3DSA:3.60.150.10 3 394 2.1E-140 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 SMALA_RS33040 f00053b3457854c17265561c61403ae4 394 TIGRFAM TIGR00033 aroC: chorismate synthase 4 374 6.7E-140 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 SMALA_RS33040 f00053b3457854c17265561c61403ae4 394 ProSitePatterns PS00787 Chorismate synthase signature 1. 10 25 - T 29-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 SMALA_RS33040 f00053b3457854c17265561c61403ae4 394 PIRSF PIRSF001456 1 386 1.3E-126 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 SMALA_RS33040 f00053b3457854c17265561c61403ae4 394 Hamap MF_00300 Chorismate synthase [aroC]. 4 376 34.238 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 SMALA_RS33040 f00053b3457854c17265561c61403ae4 394 ProSitePatterns PS00789 Chorismate synthase signature 3. 343 359 - T 29-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 SMALA_RS33040 f00053b3457854c17265561c61403ae4 394 ProSitePatterns PS00788 Chorismate synthase signature 2. 136 152 - T 29-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 SMALA_RS37480 b03924e1549f1d14735bd4f4f5bb0bab 385 Gene3D G3DSA:3.30.70.20 222 281 0.015 T 29-03-2018 SMALA_RS37480 b03924e1549f1d14735bd4f4f5bb0bab 385 Gene3D G3DSA:3.30.70.20 355 382 5.0E-4 T 29-03-2018 SMALA_RS37480 b03924e1549f1d14735bd4f4f5bb0bab 385 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 350 361 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site SMALA_RS37480 b03924e1549f1d14735bd4f4f5bb0bab 385 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 271 282 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site SMALA_RS37480 b03924e1549f1d14735bd4f4f5bb0bab 385 Gene3D G3DSA:3.30.70.20 282 354 4.2E-11 T 29-03-2018 SMALA_RS37480 b03924e1549f1d14735bd4f4f5bb0bab 385 Pfam PF17179 4Fe-4S dicluster domain 270 364 4.5E-33 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain SMALA_RS37480 b03924e1549f1d14735bd4f4f5bb0bab 385 SUPERFAMILY SSF46548 262 374 5.41E-15 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 SMALA_RS04785 79ff2aee336b3e31fc2cee1d98bdf90c 295 Pfam PF12833 Helix-turn-helix domain 216 294 5.1E-24 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS04785 79ff2aee336b3e31fc2cee1d98bdf90c 295 Gene3D G3DSA:1.10.10.60 196 250 4.9E-18 T 29-03-2018 SMALA_RS04785 79ff2aee336b3e31fc2cee1d98bdf90c 295 SUPERFAMILY SSF46689 246 295 9.68E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS04785 79ff2aee336b3e31fc2cee1d98bdf90c 295 SMART SM00342 210 293 3.1E-33 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS04785 79ff2aee336b3e31fc2cee1d98bdf90c 295 Gene3D G3DSA:1.10.10.60 251 295 3.6E-15 T 29-03-2018 SMALA_RS04785 79ff2aee336b3e31fc2cee1d98bdf90c 295 SUPERFAMILY SSF46689 194 244 2.69E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS13575 5f409a6730888f2f48388e48adc47c01 418 Pfam PF00999 Sodium/hydrogen exchanger family 18 372 3.2E-47 T 29-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 SMALA_RS13575 5f409a6730888f2f48388e48adc47c01 418 Gene3D G3DSA:1.20.91.10 229 311 6.2E-5 T 29-03-2018 SMALA_RS33685 67a26e1d99af947920f79970c06619e0 390 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 132 144 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 SMALA_RS33685 67a26e1d99af947920f79970c06619e0 390 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 15 125 1.5E-22 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS33685 67a26e1d99af947920f79970c06619e0 390 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 130 224 9.0E-27 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 SMALA_RS33685 67a26e1d99af947920f79970c06619e0 390 SUPERFAMILY SSF56645 13 248 9.03E-73 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMALA_RS33685 67a26e1d99af947920f79970c06619e0 390 Gene3D G3DSA:1.20.140.10 225 389 9.5E-61 T 29-03-2018 SMALA_RS33685 67a26e1d99af947920f79970c06619e0 390 SUPERFAMILY SSF47203 234 386 2.74E-59 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMALA_RS33685 67a26e1d99af947920f79970c06619e0 390 PIRSF PIRSF016578 6 389 1.8E-17 T 29-03-2018 SMALA_RS33685 67a26e1d99af947920f79970c06619e0 390 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 236 384 1.1E-50 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMALA_RS33685 67a26e1d99af947920f79970c06619e0 390 Gene3D G3DSA:1.10.540.10 12 130 4.9E-26 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS33685 67a26e1d99af947920f79970c06619e0 390 Gene3D G3DSA:2.40.110.10 131 224 5.1E-38 T 29-03-2018 SMALA_RS33685 67a26e1d99af947920f79970c06619e0 390 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 343 362 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 SMALA_RS13285 08d44b5b737bdbd7d647ade769b960f1 162 Gene3D G3DSA:3.40.1400.10 1 157 3.7E-56 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 SMALA_RS13285 08d44b5b737bdbd7d647ade769b960f1 162 TIGRFAM TIGR02133 RPI_actino: ribose 5-phosphate isomerase 1 148 1.1E-73 T 29-03-2018 IPR011860 Ribose 5-phosphate isomerase GO:0004751 SMALA_RS13285 08d44b5b737bdbd7d647ade769b960f1 162 Pfam PF02502 Ribose/Galactose Isomerase 3 142 1.4E-45 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 SMALA_RS13285 08d44b5b737bdbd7d647ade769b960f1 162 SUPERFAMILY SSF89623 1 152 1.7E-51 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 SMALA_RS13285 08d44b5b737bdbd7d647ade769b960f1 162 PIRSF PIRSF005384 1 149 3.8E-49 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 SMALA_RS13285 08d44b5b737bdbd7d647ade769b960f1 162 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 3 147 1.0E-51 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 SMALA_RS28775 cf0e4333c791f2d853842cd942c978ce 270 Gene3D G3DSA:1.10.8.50 119 260 3.4E-49 T 29-03-2018 SMALA_RS28775 cf0e4333c791f2d853842cd942c978ce 270 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 94 3.4E-8 T 29-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 SMALA_RS28775 cf0e4333c791f2d853842cd942c978ce 270 SUPERFAMILY SSF57716 214 259 1.06E-10 T 29-03-2018 SMALA_RS28775 cf0e4333c791f2d853842cd942c978ce 270 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 124 187 1.1E-9 T 29-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 SMALA_RS28775 cf0e4333c791f2d853842cd942c978ce 270 ProSitePatterns PS01242 Zinc finger FPG-type signature. 231 259 - T 29-03-2018 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 SMALA_RS28775 cf0e4333c791f2d853842cd942c978ce 270 Gene3D G3DSA:3.20.190.10 1 118 4.4E-26 T 29-03-2018 SMALA_RS28775 cf0e4333c791f2d853842cd942c978ce 270 SMART SM00898 2 110 1.2E-23 T 29-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 SMALA_RS28775 cf0e4333c791f2d853842cd942c978ce 270 SUPERFAMILY SSF81624 2 125 2.75E-27 T 29-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 SMALA_RS28775 cf0e4333c791f2d853842cd942c978ce 270 SUPERFAMILY SSF46946 123 188 2.06E-18 T 29-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 SMALA_RS28775 cf0e4333c791f2d853842cd942c978ce 270 SMART SM01232 124 212 1.5E-22 T 29-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 SMALA_RS14965 a67c7b3b254ec6a5b0b014b1e4855e1c 258 Pfam PF06182 ABC-2 family transporter protein 25 257 7.2E-61 T 29-03-2018 IPR010390 Protein of unknown function DUF990 SMALA_RS20325 9645e8aff72a1459d186bc8cf6059995 632 SMART SM00637 532 630 1.3E-34 T 29-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 SMALA_RS20325 9645e8aff72a1459d186bc8cf6059995 632 Pfam PF00553 Cellulose binding domain 532 630 2.0E-25 T 29-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 SMALA_RS20325 9645e8aff72a1459d186bc8cf6059995 632 Gene3D G3DSA:1.10.10.10 72 196 8.4E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS20325 9645e8aff72a1459d186bc8cf6059995 632 SUPERFAMILY SSF49384 528 630 4.81E-28 T 29-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 SMALA_RS20325 9645e8aff72a1459d186bc8cf6059995 632 Gene3D G3DSA:2.60.40.290 523 630 9.5E-31 T 29-03-2018 SMALA_RS37595 0b2e86e23684d6a251cea4a61fdc0ae2 973 SMART SM00487 502 688 4.8E-27 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain SMALA_RS37595 0b2e86e23684d6a251cea4a61fdc0ae2 973 Gene3D G3DSA:3.40.50.300 787 950 7.3E-39 T 29-03-2018 SMALA_RS37595 0b2e86e23684d6a251cea4a61fdc0ae2 973 Pfam PF12419 SNF2 Helicase protein 321 454 2.6E-40 T 29-03-2018 IPR022138 Helicase SWF/SNF-related SMALA_RS37595 0b2e86e23684d6a251cea4a61fdc0ae2 973 SUPERFAMILY SSF52540 493 716 1.0E-51 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS37595 0b2e86e23684d6a251cea4a61fdc0ae2 973 SMART SM00490 830 912 2.3E-24 T 29-03-2018 IPR001650 Helicase, C-terminal SMALA_RS37595 0b2e86e23684d6a251cea4a61fdc0ae2 973 Gene3D G3DSA:3.40.50.10810 507 717 1.6E-46 T 29-03-2018 SMALA_RS37595 0b2e86e23684d6a251cea4a61fdc0ae2 973 Pfam PF00271 Helicase conserved C-terminal domain 801 912 3.0E-17 T 29-03-2018 IPR001650 Helicase, C-terminal SMALA_RS37595 0b2e86e23684d6a251cea4a61fdc0ae2 973 Pfam PF00176 SNF2 family N-terminal domain 525 784 4.4E-49 T 29-03-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 SMALA_RS37595 0b2e86e23684d6a251cea4a61fdc0ae2 973 SUPERFAMILY SSF52540 723 969 5.45E-65 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS11450 0ae4c33f648d06508fcee528c10a17c1 371 Gene3D G3DSA:3.60.15.10 2 331 1.3E-41 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS11450 0ae4c33f648d06508fcee528c10a17c1 371 Pfam PF00753 Metallo-beta-lactamase superfamily 28 193 4.4E-13 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS11450 0ae4c33f648d06508fcee528c10a17c1 371 SUPERFAMILY SSF56281 225 363 1.21E-50 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS11450 0ae4c33f648d06508fcee528c10a17c1 371 SUPERFAMILY SSF56281 5 192 1.21E-50 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS11450 0ae4c33f648d06508fcee528c10a17c1 371 SMART SM00849 28 281 2.1E-18 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS39030 465d76f6015f9410c9840544d42516f8 278 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 93 274 8.1E-32 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS39030 465d76f6015f9410c9840544d42516f8 278 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 5 46 1.0E-8 T 29-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain SMALA_RS39030 465d76f6015f9410c9840544d42516f8 278 Gene3D G3DSA:1.10.3720.10 2 264 3.3E-43 T 29-03-2018 SMALA_RS39030 465d76f6015f9410c9840544d42516f8 278 SUPERFAMILY SSF161098 70 256 4.84E-26 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS29615 6bd0dd022c5c1ea2d3300371f83e3e19 239 SUPERFAMILY SSF51206 8 134 1.96E-22 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like SMALA_RS29615 6bd0dd022c5c1ea2d3300371f83e3e19 239 SUPERFAMILY SSF46785 146 224 6.31E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS29615 6bd0dd022c5c1ea2d3300371f83e3e19 239 Gene3D G3DSA:1.10.10.10 150 232 9.2E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS29615 6bd0dd022c5c1ea2d3300371f83e3e19 239 Gene3D G3DSA:2.60.120.10 7 149 5.7E-19 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SMALA_RS29615 6bd0dd022c5c1ea2d3300371f83e3e19 239 SMART SM00419 168 216 1.4E-9 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 SMALA_RS29615 6bd0dd022c5c1ea2d3300371f83e3e19 239 Pfam PF00027 Cyclic nucleotide-binding domain 29 114 9.3E-13 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain SMALA_RS29615 6bd0dd022c5c1ea2d3300371f83e3e19 239 Pfam PF13545 Crp-like helix-turn-helix domain 148 221 2.0E-14 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 SMALA_RS29615 6bd0dd022c5c1ea2d3300371f83e3e19 239 SMART SM00100 10 128 2.7E-11 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain SMALA_RS42570 eee3517b4ab06ad41b53b12463b9a624 570 SUPERFAMILY SSF52540 12 265 1.74E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS42570 eee3517b4ab06ad41b53b12463b9a624 570 ProSitePatterns PS00211 ABC transporters family signature. 166 180 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS42570 eee3517b4ab06ad41b53b12463b9a624 570 Pfam PF00005 ABC transporter 318 470 1.2E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS42570 eee3517b4ab06ad41b53b12463b9a624 570 Pfam PF00005 ABC transporter 37 194 3.7E-23 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS42570 eee3517b4ab06ad41b53b12463b9a624 570 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 245 277 4.8E-4 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMALA_RS42570 eee3517b4ab06ad41b53b12463b9a624 570 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 522 547 1.6E-4 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMALA_RS42570 eee3517b4ab06ad41b53b12463b9a624 570 SUPERFAMILY SSF52540 294 542 1.84E-69 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS42570 eee3517b4ab06ad41b53b12463b9a624 570 ProSitePatterns PS00211 ABC transporters family signature. 443 457 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS42570 eee3517b4ab06ad41b53b12463b9a624 570 SMART SM00382 42 243 1.9E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS42570 eee3517b4ab06ad41b53b12463b9a624 570 SMART SM00382 327 520 2.2E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS42570 eee3517b4ab06ad41b53b12463b9a624 570 Gene3D G3DSA:3.40.50.300 290 558 4.7E-70 T 29-03-2018 SMALA_RS42570 eee3517b4ab06ad41b53b12463b9a624 570 Gene3D G3DSA:3.40.50.300 9 289 1.3E-62 T 29-03-2018 SMALA_RS10680 3cde7ac6fc5bb7f632bfb627c7d10455 306 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 8.1E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS10680 3cde7ac6fc5bb7f632bfb627c7d10455 306 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 195 8.1E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS10680 3cde7ac6fc5bb7f632bfb627c7d10455 306 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 96 107 8.1E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS10680 3cde7ac6fc5bb7f632bfb627c7d10455 306 Gene3D G3DSA:3.40.50.720 5 274 4.9E-29 T 29-03-2018 SMALA_RS10680 3cde7ac6fc5bb7f632bfb627c7d10455 306 Pfam PF00106 short chain dehydrogenase 11 212 2.0E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS10680 3cde7ac6fc5bb7f632bfb627c7d10455 306 SUPERFAMILY SSF51735 7 265 4.69E-33 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS31340 afc8a53bd551ae4d3c60f3babe3e144f 393 Gene3D G3DSA:3.30.420.40 73 194 4.5E-31 T 29-03-2018 SMALA_RS31340 afc8a53bd551ae4d3c60f3babe3e144f 393 SUPERFAMILY SSF46785 8 69 1.66E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS31340 afc8a53bd551ae4d3c60f3babe3e144f 393 Gene3D G3DSA:1.10.10.10 5 72 7.2E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS31340 afc8a53bd551ae4d3c60f3babe3e144f 393 Gene3D G3DSA:3.30.420.40 195 392 2.2E-56 T 29-03-2018 SMALA_RS31340 afc8a53bd551ae4d3c60f3babe3e144f 393 ProSitePatterns PS01125 ROK family signature. 209 236 - T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 SMALA_RS31340 afc8a53bd551ae4d3c60f3babe3e144f 393 Pfam PF00480 ROK family 78 386 8.6E-60 T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 SMALA_RS31340 afc8a53bd551ae4d3c60f3babe3e144f 393 SUPERFAMILY SSF53067 76 389 1.73E-60 T 29-03-2018 SMALA_RS37535 7f61abc45f50230eddd384c085eb13c2 392 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 216 373 3.2E-19 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMALA_RS37535 7f61abc45f50230eddd384c085eb13c2 392 Gene3D G3DSA:1.10.540.10 2 106 9.8E-18 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS37535 7f61abc45f50230eddd384c085eb13c2 392 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 4 106 1.9E-9 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS37535 7f61abc45f50230eddd384c085eb13c2 392 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 110 193 3.3E-19 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 SMALA_RS37535 7f61abc45f50230eddd384c085eb13c2 392 Gene3D G3DSA:2.40.110.10 107 203 1.8E-31 T 29-03-2018 SMALA_RS37535 7f61abc45f50230eddd384c085eb13c2 392 Gene3D G3DSA:1.20.140.10 204 386 2.0E-33 T 29-03-2018 SMALA_RS37535 7f61abc45f50230eddd384c085eb13c2 392 SUPERFAMILY SSF56645 6 229 1.11E-62 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMALA_RS37535 7f61abc45f50230eddd384c085eb13c2 392 SUPERFAMILY SSF47203 216 375 2.62E-16 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMALA_RS09615 7f86fdd29be24baf3823b195374332c2 352 Gene3D G3DSA:3.40.50.2300 177 335 1.1E-43 T 29-03-2018 SMALA_RS09615 7f86fdd29be24baf3823b195374332c2 352 Gene3D G3DSA:3.40.50.2300 56 176 3.2E-38 T 29-03-2018 SMALA_RS09615 7f86fdd29be24baf3823b195374332c2 352 SUPERFAMILY SSF47413 1 59 1.06E-17 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS09615 7f86fdd29be24baf3823b195374332c2 352 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 29-03-2018 SMALA_RS09615 7f86fdd29be24baf3823b195374332c2 352 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 2.7E-5 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS09615 7f86fdd29be24baf3823b195374332c2 352 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 2.7E-5 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS09615 7f86fdd29be24baf3823b195374332c2 352 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 6.3E-17 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS09615 7f86fdd29be24baf3823b195374332c2 352 SMART SM00354 1 71 9.5E-30 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS09615 7f86fdd29be24baf3823b195374332c2 352 SUPERFAMILY SSF53822 60 330 8.44E-76 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SMALA_RS09615 7f86fdd29be24baf3823b195374332c2 352 Pfam PF13377 Periplasmic binding protein-like domain 167 328 7.5E-39 T 29-03-2018 SMALA_RS09615 7f86fdd29be24baf3823b195374332c2 352 Gene3D G3DSA:1.10.260.40 2 55 4.4E-23 T 29-03-2018 SMALA_RS16370 0834c678d1c5b4ee19ed56ca1961caa6 197 SUPERFAMILY SSF48498 91 196 3.81E-12 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS16370 0834c678d1c5b4ee19ed56ca1961caa6 197 Gene3D G3DSA:1.10.357.10 7 197 2.8E-33 T 29-03-2018 SMALA_RS16370 0834c678d1c5b4ee19ed56ca1961caa6 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 39 6.5E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS16370 0834c678d1c5b4ee19ed56ca1961caa6 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 6.5E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS16370 0834c678d1c5b4ee19ed56ca1961caa6 197 SUPERFAMILY SSF46689 11 92 6.62E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS16370 0834c678d1c5b4ee19ed56ca1961caa6 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 71 2.5E-13 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS33240 a20e0860643e5ee0f9040752ed212675 265 Gene3D G3DSA:3.60.110.10 1 265 5.4E-66 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMALA_RS33240 a20e0860643e5ee0f9040752ed212675 265 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 143 163 - T 29-03-2018 IPR001110 Uncharacterised protein family UPF0012, conserved site SMALA_RS33240 a20e0860643e5ee0f9040752ed212675 265 SUPERFAMILY SSF56317 1 262 5.23E-66 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMALA_RS33240 a20e0860643e5ee0f9040752ed212675 265 Pfam PF00795 Carbon-nitrogen hydrolase 5 246 2.1E-39 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMALA_RS05605 91f2344e98f50a8910e457bd80656f8c 311 Gene3D G3DSA:3.30.2010.10 98 186 4.2E-17 T 29-03-2018 SMALA_RS05605 91f2344e98f50a8910e457bd80656f8c 311 Pfam PF01435 Peptidase family M48 116 185 2.4E-10 T 29-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 SMALA_RS04210 955b9ea303020a970fdc47a7bb200aa8 419 Pfam PF07690 Major Facilitator Superfamily 4 373 3.5E-45 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS04210 955b9ea303020a970fdc47a7bb200aa8 419 Gene3D G3DSA:1.20.1250.20 221 418 6.3E-20 T 29-03-2018 SMALA_RS04210 955b9ea303020a970fdc47a7bb200aa8 419 SUPERFAMILY SSF103473 2 409 4.05E-71 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS04210 955b9ea303020a970fdc47a7bb200aa8 419 Gene3D G3DSA:1.20.1250.20 1 199 2.2E-29 T 29-03-2018 SMALA_RS39525 ca80c89eaa0ee0c7194734cb10845ba3 3631 SUPERFAMILY SSF56801 119 662 1.06E-142 T 29-03-2018 SMALA_RS39525 ca80c89eaa0ee0c7194734cb10845ba3 3631 SUPERFAMILY SSF52777 2790 3020 2.45E-49 T 29-03-2018 SMALA_RS39525 ca80c89eaa0ee0c7194734cb10845ba3 3631 SUPERFAMILY SSF52777 1192 1382 1.07E-34 T 29-03-2018 SMALA_RS39525 ca80c89eaa0ee0c7194734cb10845ba3 3631 Gene3D G3DSA:3.40.50.980 3195 3351 2.0E-26 T 29-03-2018 SMALA_RS39525 ca80c89eaa0ee0c7194734cb10845ba3 3631 Gene3D G3DSA:3.30.1110.20 1780 1804 3.5E-8 T 29-03-2018 SMALA_RS39525 ca80c89eaa0ee0c7194734cb10845ba3 3631 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2166 2181 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS39525 ca80c89eaa0ee0c7194734cb10845ba3 3631 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 3072 3473 6.8E-108 T 29-03-2018 IPR010071 Amino acid adenylation domain SMALA_RS39525 ca80c89eaa0ee0c7194734cb10845ba3 3631 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 166 566 2.3E-116 T 29-03-2018 IPR010071 Amino acid adenylation domain SMALA_RS39525 ca80c89eaa0ee0c7194734cb10845ba3 3631 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1652 2062 9.0E-127 T 29-03-2018 IPR010071 Amino acid adenylation domain SMALA_RS39525 ca80c89eaa0ee0c7194734cb10845ba3 3631 Gene3D G3DSA:3.30.300.30 2033 2146 1.9E-25 T 29-03-2018 SMALA_RS39525 ca80c89eaa0ee0c7194734cb10845ba3 3631 Gene3D G3DSA:3.30.300.30 537 656 3.4E-31 T 29-03-2018 SMALA_RS39525 ca80c89eaa0ee0c7194734cb10845ba3 3631 Gene3D G3DSA:3.30.300.30 3445 3565 4.5E-28 T 29-03-2018 SMALA_RS39525 ca80c89eaa0ee0c7194734cb10845ba3 3631 Gene3D G3DSA:2.30.38.10 451 532 6.6E-21 T 29-03-2018 SMALA_RS39525 ca80c89eaa0ee0c7194734cb10845ba3 3631 Gene3D G3DSA:3.30.559.10 713 907 1.1E-21 T 29-03-2018 SMALA_RS39525 ca80c89eaa0ee0c7194734cb10845ba3 3631 Gene3D G3DSA:3.30.559.10 2218 2392 6.7E-20 T 29-03-2018 SMALA_RS39525 ca80c89eaa0ee0c7194734cb10845ba3 3631 SUPERFAMILY SSF47336 3555 3629 2.22E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS39525 ca80c89eaa0ee0c7194734cb10845ba3 3631 SUPERFAMILY SSF47336 643 712 5.76E-16 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS39525 ca80c89eaa0ee0c7194734cb10845ba3 3631 Gene3D G3DSA:3.30.559.10 2597 2799 1.6E-33 T 29-03-2018 SMALA_RS39525 ca80c89eaa0ee0c7194734cb10845ba3 3631 Gene3D G3DSA:3.30.559.10 1176 1375 3.3E-33 T 29-03-2018 SMALA_RS39525 ca80c89eaa0ee0c7194734cb10845ba3 3631 Gene3D G3DSA:1.10.1200.10 657 712 2.0E-18 T 29-03-2018 SMALA_RS39525 ca80c89eaa0ee0c7194734cb10845ba3 3631 Pfam PF00501 AMP-binding enzyme 1626 2037 3.1E-94 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS39525 ca80c89eaa0ee0c7194734cb10845ba3 3631 Pfam PF00501 AMP-binding enzyme 145 542 1.4E-95 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS39525 ca80c89eaa0ee0c7194734cb10845ba3 3631 Pfam PF00501 AMP-binding enzyme 3051 3450 3.7E-87 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS39525 ca80c89eaa0ee0c7194734cb10845ba3 3631 SUPERFAMILY SSF47336 2138 2206 2.75E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS39525 ca80c89eaa0ee0c7194734cb10845ba3 3631 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1774 1785 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS39525 ca80c89eaa0ee0c7194734cb10845ba3 3631 SMART SM00823 Phosphopantetheine attachment site 650 718 5.9E-8 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS39525 ca80c89eaa0ee0c7194734cb10845ba3 3631 SMART SM00823 Phosphopantetheine attachment site 3560 3631 0.0025 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS39525 ca80c89eaa0ee0c7194734cb10845ba3 3631 SMART SM00823 Phosphopantetheine attachment site 2143 2210 4.6E-4 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS39525 ca80c89eaa0ee0c7194734cb10845ba3 3631 SUPERFAMILY SSF52777 1368 1608 1.22E-43 T 29-03-2018 SMALA_RS39525 ca80c89eaa0ee0c7194734cb10845ba3 3631 Pfam PF00668 Condensation domain 2611 3019 1.2E-69 T 29-03-2018 IPR001242 Condensation domain SMALA_RS39525 ca80c89eaa0ee0c7194734cb10845ba3 3631 Pfam PF00668 Condensation domain 1193 1606 4.5E-58 T 29-03-2018 IPR001242 Condensation domain SMALA_RS39525 ca80c89eaa0ee0c7194734cb10845ba3 3631 Pfam PF00668 Condensation domain 750 1161 1.5E-29 T 29-03-2018 IPR001242 Condensation domain SMALA_RS39525 ca80c89eaa0ee0c7194734cb10845ba3 3631 Pfam PF00668 Condensation domain 2254 2571 9.4E-24 T 29-03-2018 IPR001242 Condensation domain SMALA_RS39525 ca80c89eaa0ee0c7194734cb10845ba3 3631 SUPERFAMILY SSF56801 3042 3572 9.16E-126 T 29-03-2018 SMALA_RS39525 ca80c89eaa0ee0c7194734cb10845ba3 3631 Gene3D G3DSA:3.40.50.980 1805 1934 3.4E-29 T 29-03-2018 SMALA_RS39525 ca80c89eaa0ee0c7194734cb10845ba3 3631 Gene3D G3DSA:2.30.38.10 1950 2031 9.8E-21 T 29-03-2018 SMALA_RS39525 ca80c89eaa0ee0c7194734cb10845ba3 3631 Gene3D G3DSA:2.30.38.10 3362 3443 3.1E-22 T 29-03-2018 SMALA_RS39525 ca80c89eaa0ee0c7194734cb10845ba3 3631 SUPERFAMILY SSF52777 2227 2400 6.34E-22 T 29-03-2018 SMALA_RS39525 ca80c89eaa0ee0c7194734cb10845ba3 3631 Gene3D G3DSA:3.40.50.980 136 288 1.1E-37 T 29-03-2018 SMALA_RS39525 ca80c89eaa0ee0c7194734cb10845ba3 3631 SUPERFAMILY SSF52777 898 1162 3.56E-27 T 29-03-2018 SMALA_RS39525 ca80c89eaa0ee0c7194734cb10845ba3 3631 Gene3D G3DSA:3.40.50.980 1619 1779 7.1E-43 T 29-03-2018 SMALA_RS39525 ca80c89eaa0ee0c7194734cb10845ba3 3631 Gene3D G3DSA:3.40.50.980 3044 3194 1.0E-42 T 29-03-2018 SMALA_RS39525 ca80c89eaa0ee0c7194734cb10845ba3 3631 SUPERFAMILY SSF56801 1604 2128 4.19E-141 T 29-03-2018 SMALA_RS39525 ca80c89eaa0ee0c7194734cb10845ba3 3631 Gene3D G3DSA:3.40.50.980 289 440 1.1E-38 T 29-03-2018 SMALA_RS39525 ca80c89eaa0ee0c7194734cb10845ba3 3631 SUPERFAMILY SSF52777 734 890 4.45E-25 T 29-03-2018 SMALA_RS39525 ca80c89eaa0ee0c7194734cb10845ba3 3631 Pfam PF13193 AMP-binding enzyme C-terminal domain 3458 3532 2.0E-10 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS39525 ca80c89eaa0ee0c7194734cb10845ba3 3631 Pfam PF13193 AMP-binding enzyme C-terminal domain 2046 2113 7.6E-7 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS39525 ca80c89eaa0ee0c7194734cb10845ba3 3631 Pfam PF13193 AMP-binding enzyme C-terminal domain 551 626 1.9E-14 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS39525 ca80c89eaa0ee0c7194734cb10845ba3 3631 SUPERFAMILY SSF52777 2391 2606 2.11E-18 T 29-03-2018 SMALA_RS39525 ca80c89eaa0ee0c7194734cb10845ba3 3631 Gene3D G3DSA:1.10.1200.10 3566 3631 1.7E-16 T 29-03-2018 SMALA_RS39525 ca80c89eaa0ee0c7194734cb10845ba3 3631 Gene3D G3DSA:1.10.1200.10 2147 2217 5.8E-15 T 29-03-2018 SMALA_RS39525 ca80c89eaa0ee0c7194734cb10845ba3 3631 SUPERFAMILY SSF52777 2617 2788 1.08E-36 T 29-03-2018 SMALA_RS39525 ca80c89eaa0ee0c7194734cb10845ba3 3631 ProSitePatterns PS00455 Putative AMP-binding domain signature. 284 295 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS39525 ca80c89eaa0ee0c7194734cb10845ba3 3631 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 1036 1186 9.3E-36 T 29-03-2018 IPR010060 Non-ribosomal peptide synthase SMALA_RS39525 ca80c89eaa0ee0c7194734cb10845ba3 3631 Pfam PF00550 Phosphopantetheine attachment site 3562 3627 1.3E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS39525 ca80c89eaa0ee0c7194734cb10845ba3 3631 Pfam PF00550 Phosphopantetheine attachment site 652 712 1.0E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS39525 ca80c89eaa0ee0c7194734cb10845ba3 3631 Pfam PF00550 Phosphopantetheine attachment site 2144 2204 1.6E-7 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS39525 ca80c89eaa0ee0c7194734cb10845ba3 3631 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3586 3601 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS30035 35701212212785239d1cd7262676cc3f 302 SUPERFAMILY SSF55729 44 295 7.56E-13 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS30035 35701212212785239d1cd7262676cc3f 302 Gene3D G3DSA:3.40.630.30 152 301 1.5E-15 T 29-03-2018 SMALA_RS30035 35701212212785239d1cd7262676cc3f 302 Gene3D G3DSA:3.40.630.30 1 79 1.3E-6 T 29-03-2018 SMALA_RS08365 2aad3d55a255fd9cf66a1b3a7ebe2301 266 SUPERFAMILY SSF55909 11 262 3.93E-56 T 29-03-2018 SMALA_RS08365 2aad3d55a255fd9cf66a1b3a7ebe2301 266 Pfam PF02274 Amidinotransferase 65 193 7.6E-8 T 29-03-2018 SMALA_RS08365 2aad3d55a255fd9cf66a1b3a7ebe2301 266 Gene3D G3DSA:3.75.10.10 10 261 7.0E-50 T 29-03-2018 SMALA_RS23645 b1655beca0797682195eac3597509558 502 ProSitePatterns PS00216 Sugar transport proteins signature 1. 69 85 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMALA_RS23645 b1655beca0797682195eac3597509558 502 Gene3D G3DSA:1.20.1250.20 262 480 3.0E-25 T 29-03-2018 SMALA_RS23645 b1655beca0797682195eac3597509558 502 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 16 453 5.0E-77 T 29-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 SMALA_RS23645 b1655beca0797682195eac3597509558 502 Gene3D G3DSA:1.20.1250.20 3 201 6.7E-35 T 29-03-2018 SMALA_RS23645 b1655beca0797682195eac3597509558 502 SUPERFAMILY SSF103473 251 474 2.22E-67 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS23645 b1655beca0797682195eac3597509558 502 SUPERFAMILY SSF103473 7 199 2.22E-67 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS23645 b1655beca0797682195eac3597509558 502 PRINTS PR01036 Tetracycline resistance protein TetB signature 140 164 4.1E-6 T 29-03-2018 SMALA_RS23645 b1655beca0797682195eac3597509558 502 PRINTS PR01036 Tetracycline resistance protein TetB signature 18 42 4.1E-6 T 29-03-2018 SMALA_RS23645 b1655beca0797682195eac3597509558 502 PRINTS PR01036 Tetracycline resistance protein TetB signature 206 224 4.1E-6 T 29-03-2018 SMALA_RS23645 b1655beca0797682195eac3597509558 502 Pfam PF07690 Major Facilitator Superfamily 19 414 8.0E-54 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS37405 1233eaa2951a0b07e85e0b44961f212d 161 SMART SM00900 82 159 5.7E-13 T 29-03-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 SMALA_RS37405 1233eaa2951a0b07e85e0b44961f212d 161 Pfam PF04205 FMN-binding domain 84 156 1.2E-9 T 29-03-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 SMALA_RS06440 e38bdda5abbc5f9c12c99cdbc4f60a47 2093 SUPERFAMILY SSF47336 1941 2025 8.24E-23 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS06440 e38bdda5abbc5f9c12c99cdbc4f60a47 2093 Pfam PF08659 KR domain 1670 1845 1.2E-58 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS06440 e38bdda5abbc5f9c12c99cdbc4f60a47 2093 Gene3D G3DSA:3.40.47.10 26 296 3.6E-83 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS06440 e38bdda5abbc5f9c12c99cdbc4f60a47 2093 SMART SM00825 Beta-ketoacyl synthase 36 461 2.5E-213 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS06440 e38bdda5abbc5f9c12c99cdbc4f60a47 2093 Pfam PF00550 Phosphopantetheine attachment site 1950 2016 1.5E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS06440 e38bdda5abbc5f9c12c99cdbc4f60a47 2093 SUPERFAMILY SSF55048 693 755 1.57E-8 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS06440 e38bdda5abbc5f9c12c99cdbc4f60a47 2093 SUPERFAMILY SSF51735 1138 1335 9.45E-18 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS06440 e38bdda5abbc5f9c12c99cdbc4f60a47 2093 Gene3D G3DSA:3.90.180.10 1330 1665 1.2E-60 T 29-03-2018 SMALA_RS06440 e38bdda5abbc5f9c12c99cdbc4f60a47 2093 Pfam PF00698 Acyl transferase domain 569 883 2.3E-74 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS06440 e38bdda5abbc5f9c12c99cdbc4f60a47 2093 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 1378 1433 6.1E-6 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS06440 e38bdda5abbc5f9c12c99cdbc4f60a47 2093 Gene3D G3DSA:3.40.366.10 754 876 6.1E-23 T 29-03-2018 SMALA_RS06440 e38bdda5abbc5f9c12c99cdbc4f60a47 2093 Gene3D G3DSA:3.40.366.10 557 753 3.0E-48 T 29-03-2018 SMALA_RS06440 e38bdda5abbc5f9c12c99cdbc4f60a47 2093 SUPERFAMILY SSF50129 1366 1491 7.23E-28 T 29-03-2018 IPR011032 GroES-like SMALA_RS06440 e38bdda5abbc5f9c12c99cdbc4f60a47 2093 SMART SM00826 931 1089 3.8E-69 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS06440 e38bdda5abbc5f9c12c99cdbc4f60a47 2093 Pfam PF13602 Zinc-binding dehydrogenase 1533 1662 3.9E-14 T 29-03-2018 SMALA_RS06440 e38bdda5abbc5f9c12c99cdbc4f60a47 2093 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1670 1847 3.4E-52 T 29-03-2018 SMALA_RS06440 e38bdda5abbc5f9c12c99cdbc4f60a47 2093 Pfam PF14765 Polyketide synthase dehydratase 931 1199 2.3E-55 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS06440 e38bdda5abbc5f9c12c99cdbc4f60a47 2093 SUPERFAMILY SSF51735 1457 1595 5.92E-36 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS06440 e38bdda5abbc5f9c12c99cdbc4f60a47 2093 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 284 1.0E-88 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS06440 e38bdda5abbc5f9c12c99cdbc4f60a47 2093 SUPERFAMILY SSF53901 31 405 7.21E-104 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS06440 e38bdda5abbc5f9c12c99cdbc4f60a47 2093 Gene3D G3DSA:1.10.1200.10 1931 2026 5.2E-21 T 29-03-2018 SMALA_RS06440 e38bdda5abbc5f9c12c99cdbc4f60a47 2093 Gene3D G3DSA:3.10.129.10 932 1053 9.0E-10 T 29-03-2018 SMALA_RS06440 e38bdda5abbc5f9c12c99cdbc4f60a47 2093 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 410 543 5.4E-16 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS06440 e38bdda5abbc5f9c12c99cdbc4f60a47 2093 SMART SM00829 1359 1662 1.1E-177 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS06440 e38bdda5abbc5f9c12c99cdbc4f60a47 2093 SUPERFAMILY SSF51735 1667 1864 4.24E-41 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS06440 e38bdda5abbc5f9c12c99cdbc4f60a47 2093 Pfam PF08990 Erythronolide synthase docking 3 27 5.7E-8 T 29-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 SMALA_RS06440 e38bdda5abbc5f9c12c99cdbc4f60a47 2093 Gene3D G3DSA:3.40.47.10 299 459 2.8E-65 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS06440 e38bdda5abbc5f9c12c99cdbc4f60a47 2093 SMART SM01294 1949 2016 4.1E-5 T 29-03-2018 SMALA_RS06440 e38bdda5abbc5f9c12c99cdbc4f60a47 2093 SMART SM00823 Phosphopantetheine attachment site 1948 2020 7.5E-33 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS06440 e38bdda5abbc5f9c12c99cdbc4f60a47 2093 Gene3D G3DSA:3.40.50.720 1666 1906 2.1E-46 T 29-03-2018 SMALA_RS06440 e38bdda5abbc5f9c12c99cdbc4f60a47 2093 SUPERFAMILY SSF52151 762 859 3.4E-66 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS06440 e38bdda5abbc5f9c12c99cdbc4f60a47 2093 SUPERFAMILY SSF52151 566 695 3.4E-66 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS06440 e38bdda5abbc5f9c12c99cdbc4f60a47 2093 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 197 213 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS06440 e38bdda5abbc5f9c12c99cdbc4f60a47 2093 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 292 407 1.4E-45 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS06440 e38bdda5abbc5f9c12c99cdbc4f60a47 2093 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 570 1048 4.6E-92 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS32895 cc50cebf2f4c547b92f55e31f91ca96c 306 Gene3D G3DSA:3.20.20.70 30 283 9.6E-70 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS32895 cc50cebf2f4c547b92f55e31f91ca96c 306 TIGRFAM TIGR00343 TIGR00343: pyridoxal 5'-phosphate synthase, synthase subunit Pdx1 21 306 3.6E-141 T 29-03-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 SMALA_RS32895 cc50cebf2f4c547b92f55e31f91ca96c 306 ProSitePatterns PS01235 PdxS/SNZ family signature. 217 235 - T 29-03-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 SMALA_RS32895 cc50cebf2f4c547b92f55e31f91ca96c 306 Hamap MF_01824 Pyridoxal 5'-phosphate synthase subunit PdxS [pdxS]. 16 306 51.936 T 29-03-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 SMALA_RS32895 cc50cebf2f4c547b92f55e31f91ca96c 306 PIRSF PIRSF029271 7 306 2.1E-150 T 29-03-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 SMALA_RS32895 cc50cebf2f4c547b92f55e31f91ca96c 306 SUPERFAMILY SSF51366 30 276 8.95E-62 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 SMALA_RS32895 cc50cebf2f4c547b92f55e31f91ca96c 306 Pfam PF01680 SOR/SNZ family 19 224 2.2E-106 T 29-03-2018 IPR033755 PdxS/SNZ N-terminal domain KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 SMALA_RS24050 2f043877c41e0e219033b079514884f3 199 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 4 95 2.0E-24 T 29-03-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 SMALA_RS24050 2f043877c41e0e219033b079514884f3 199 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 7 178 4.3E-38 T 29-03-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 SMALA_RS24050 2f043877c41e0e219033b079514884f3 199 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 100 180 2.1E-19 T 29-03-2018 IPR020057 Ribosomal protein L25, beta domain SMALA_RS24050 2f043877c41e0e219033b079514884f3 199 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 4 181 25.827 T 29-03-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 SMALA_RS24050 2f043877c41e0e219033b079514884f3 199 Gene3D G3DSA:2.170.120.20 99 185 4.8E-22 T 29-03-2018 IPR020057 Ribosomal protein L25, beta domain SMALA_RS24050 2f043877c41e0e219033b079514884f3 199 SUPERFAMILY SSF50715 4 187 1.1E-45 T 29-03-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 SMALA_RS24050 2f043877c41e0e219033b079514884f3 199 Gene3D G3DSA:2.40.240.10 3 95 1.2E-24 T 29-03-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 SMALA_RS24050 2f043877c41e0e219033b079514884f3 199 Pfam PF01386 Ribosomal L25p family 6 92 2.3E-22 T 29-03-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 SMALA_RS10660 162641d81646b954abf378f0ce5bc3b0 585 Pfam PF00364 Biotin-requiring enzyme 127 199 1.6E-20 T 29-03-2018 IPR000089 Biotin/lipoyl attachment SMALA_RS10660 162641d81646b954abf378f0ce5bc3b0 585 Pfam PF00364 Biotin-requiring enzyme 5 76 2.0E-21 T 29-03-2018 IPR000089 Biotin/lipoyl attachment SMALA_RS10660 162641d81646b954abf378f0ce5bc3b0 585 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 150 179 - T 29-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 SMALA_RS10660 162641d81646b954abf378f0ce5bc3b0 585 Gene3D G3DSA:3.30.559.10 330 578 9.2E-76 T 29-03-2018 SMALA_RS10660 162641d81646b954abf378f0ce5bc3b0 585 TIGRFAM TIGR02927 SucB_Actino: 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase 1 585 7.7E-232 T 29-03-2018 IPR014276 2-oxoglutarate dehydrogenase, E2 component KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00620+2.3.1.12 SMALA_RS10660 162641d81646b954abf378f0ce5bc3b0 585 SUPERFAMILY SSF51230 126 219 6.28E-27 T 29-03-2018 IPR011053 Single hybrid motif SMALA_RS10660 162641d81646b954abf378f0ce5bc3b0 585 Pfam PF02817 e3 binding domain 282 314 6.2E-15 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 SMALA_RS10660 162641d81646b954abf378f0ce5bc3b0 585 Gene3D G3DSA:4.10.320.10 276 327 5.3E-20 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 SMALA_RS10660 162641d81646b954abf378f0ce5bc3b0 585 SUPERFAMILY SSF47005 275 318 3.14E-12 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 SMALA_RS10660 162641d81646b954abf378f0ce5bc3b0 585 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 349 576 1.9E-71 T 29-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 SMALA_RS10660 162641d81646b954abf378f0ce5bc3b0 585 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 29-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 SMALA_RS10660 162641d81646b954abf378f0ce5bc3b0 585 PRINTS PR01217 Proline rich extensin signature 98 114 7.3E-12 T 29-03-2018 SMALA_RS10660 162641d81646b954abf378f0ce5bc3b0 585 PRINTS PR01217 Proline rich extensin signature 81 93 7.3E-12 T 29-03-2018 SMALA_RS10660 162641d81646b954abf378f0ce5bc3b0 585 PRINTS PR01217 Proline rich extensin signature 206 222 7.3E-12 T 29-03-2018 SMALA_RS10660 162641d81646b954abf378f0ce5bc3b0 585 PRINTS PR01217 Proline rich extensin signature 243 268 7.3E-12 T 29-03-2018 SMALA_RS10660 162641d81646b954abf378f0ce5bc3b0 585 PRINTS PR01217 Proline rich extensin signature 225 242 7.3E-12 T 29-03-2018 SMALA_RS10660 162641d81646b954abf378f0ce5bc3b0 585 SUPERFAMILY SSF52777 336 576 4.45E-77 T 29-03-2018 SMALA_RS10660 162641d81646b954abf378f0ce5bc3b0 585 SUPERFAMILY SSF51230 1 96 1.96E-27 T 29-03-2018 IPR011053 Single hybrid motif SMALA_RS10660 162641d81646b954abf378f0ce5bc3b0 585 Gene3D G3DSA:3.90.1170.30 46 170 6.6E-37 T 29-03-2018 SMALA_RS10660 162641d81646b954abf378f0ce5bc3b0 585 Gene3D G3DSA:3.90.1170.30 1 45 2.5E-18 T 29-03-2018 SMALA_RS17190 68f4edf75ecd91aa6590b20b7ab466a2 233 ProSitePatterns PS01064 Pyridoxamine 5'-phosphate oxidase signature. 199 212 - T 29-03-2018 IPR019740 Pyridoxamine 5'-phosphate oxidase, conserved site GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 SMALA_RS17190 68f4edf75ecd91aa6590b20b7ab466a2 233 SUPERFAMILY SSF50475 32 233 2.05E-65 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS17190 68f4edf75ecd91aa6590b20b7ab466a2 233 Pfam PF10590 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region 189 233 3.4E-20 T 29-03-2018 IPR019576 Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 SMALA_RS17190 68f4edf75ecd91aa6590b20b7ab466a2 233 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 59 132 2.2E-20 T 29-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 SMALA_RS17190 68f4edf75ecd91aa6590b20b7ab466a2 233 Gene3D G3DSA:2.30.110.10 27 233 4.9E-73 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS17190 68f4edf75ecd91aa6590b20b7ab466a2 233 Hamap MF_01629 Pyridoxine/pyridoxamine 5'-phosphate oxidase [pdxH]. 26 233 39.7 T 29-03-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 SMALA_RS17190 68f4edf75ecd91aa6590b20b7ab466a2 233 PIRSF PIRSF000190 12 233 8.2E-82 T 29-03-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 SMALA_RS17190 68f4edf75ecd91aa6590b20b7ab466a2 233 TIGRFAM TIGR00558 pdxH: pyridoxamine 5'-phosphate oxidase 21 233 5.8E-80 T 29-03-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 SMALA_RS34885 6ec47fc6273f65d8098644fd3f8596b7 218 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 67 1.7E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS34885 6ec47fc6273f65d8098644fd3f8596b7 218 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 35 4.9E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS34885 6ec47fc6273f65d8098644fd3f8596b7 218 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 4.9E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS34885 6ec47fc6273f65d8098644fd3f8596b7 218 SUPERFAMILY SSF46689 12 86 1.64E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS34885 6ec47fc6273f65d8098644fd3f8596b7 218 SUPERFAMILY SSF48498 89 206 4.54E-15 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS34885 6ec47fc6273f65d8098644fd3f8596b7 218 ProSitePatterns PS01081 TetR-type HTH domain signature. 34 63 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site SMALA_RS34885 6ec47fc6273f65d8098644fd3f8596b7 218 Gene3D G3DSA:1.10.357.10 63 210 1.7E-20 T 29-03-2018 SMALA_RS34885 6ec47fc6273f65d8098644fd3f8596b7 218 Gene3D G3DSA:1.10.10.60 3 62 2.5E-16 T 29-03-2018 SMALA_RS21380 1f7d5e5a12248164190d1e16a5c79146 105 Pfam PF10724 Protein of unknown function (DUF2516) 2 83 1.7E-29 T 29-03-2018 IPR019662 Protein of unknown function DUF2516 SMALA_RS12640 d9412ba7793095cc382754eaf896efbe 1170 SUPERFAMILY SSF48452 1021 1142 6.58E-15 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS12640 d9412ba7793095cc382754eaf896efbe 1170 Gene3D G3DSA:1.25.40.10 861 922 3.9E-4 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS12640 d9412ba7793095cc382754eaf896efbe 1170 Pfam PF13424 Tetratricopeptide repeat 1068 1131 1.3E-10 T 29-03-2018 SMALA_RS12640 d9412ba7793095cc382754eaf896efbe 1170 Pfam PF13424 Tetratricopeptide repeat 900 970 4.8E-12 T 29-03-2018 SMALA_RS12640 d9412ba7793095cc382754eaf896efbe 1170 Pfam PF13374 Tetratricopeptide repeat 983 1023 0.014 T 29-03-2018 SMALA_RS12640 d9412ba7793095cc382754eaf896efbe 1170 Pfam PF13374 Tetratricopeptide repeat 1026 1062 2.8E-4 T 29-03-2018 SMALA_RS12640 d9412ba7793095cc382754eaf896efbe 1170 Pfam PF13374 Tetratricopeptide repeat 652 684 0.0022 T 29-03-2018 SMALA_RS12640 d9412ba7793095cc382754eaf896efbe 1170 SUPERFAMILY SSF48452 770 919 4.93E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS12640 d9412ba7793095cc382754eaf896efbe 1170 Gene3D G3DSA:1.10.10.10 799 860 0.0095 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS12640 d9412ba7793095cc382754eaf896efbe 1170 Gene3D G3DSA:1.10.10.10 1088 1169 1.2E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS12640 d9412ba7793095cc382754eaf896efbe 1170 Gene3D G3DSA:1.10.10.10 1049 1087 3.3E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS12640 d9412ba7793095cc382754eaf896efbe 1170 Gene3D G3DSA:1.10.10.10 627 690 6.9E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS12640 d9412ba7793095cc382754eaf896efbe 1170 Gene3D G3DSA:1.10.10.10 691 741 0.0052 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS12640 d9412ba7793095cc382754eaf896efbe 1170 Gene3D G3DSA:1.10.10.10 744 798 1.4E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS12640 d9412ba7793095cc382754eaf896efbe 1170 Gene3D G3DSA:1.10.10.10 923 987 1.3E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS12640 d9412ba7793095cc382754eaf896efbe 1170 Gene3D G3DSA:1.20.1250.10 988 1048 4.2E-4 T 29-03-2018 SMALA_RS12640 d9412ba7793095cc382754eaf896efbe 1170 SUPERFAMILY SSF48452 894 1013 2.71E-15 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS20150 da433fc179c151702afb9e848d836bcb 603 SUPERFAMILY SSF55261 297 414 1.05E-32 T 29-03-2018 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 SMALA_RS20150 da433fc179c151702afb9e848d836bcb 603 SUPERFAMILY SSF55681 115 298 4.15E-94 T 29-03-2018 SMALA_RS20150 da433fc179c151702afb9e848d836bcb 603 SUPERFAMILY SSF55681 422 583 4.15E-94 T 29-03-2018 SMALA_RS20150 da433fc179c151702afb9e848d836bcb 603 Pfam PF02938 GAD domain 316 403 2.0E-19 T 29-03-2018 IPR029351 GAD domain Reactome: R-HSA-379726 SMALA_RS20150 da433fc179c151702afb9e848d836bcb 603 Gene3D G3DSA:2.40.50.140 1 110 2.6E-26 T 29-03-2018 SMALA_RS20150 da433fc179c151702afb9e848d836bcb 603 Gene3D G3DSA:3.30.930.10 135 584 2.0E-92 T 29-03-2018 SMALA_RS20150 da433fc179c151702afb9e848d836bcb 603 PRINTS PR01042 Aspartyl-tRNA synthetase signature 472 488 4.2E-21 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMALA_RS20150 da433fc179c151702afb9e848d836bcb 603 PRINTS PR01042 Aspartyl-tRNA synthetase signature 516 530 4.2E-21 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMALA_RS20150 da433fc179c151702afb9e848d836bcb 603 PRINTS PR01042 Aspartyl-tRNA synthetase signature 211 224 4.2E-21 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMALA_RS20150 da433fc179c151702afb9e848d836bcb 603 PRINTS PR01042 Aspartyl-tRNA synthetase signature 194 206 4.2E-21 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMALA_RS20150 da433fc179c151702afb9e848d836bcb 603 Pfam PF01336 OB-fold nucleic acid binding domain 21 104 1.8E-15 T 29-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 SMALA_RS20150 da433fc179c151702afb9e848d836bcb 603 SUPERFAMILY SSF50249 4 107 1.63E-28 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMALA_RS20150 da433fc179c151702afb9e848d836bcb 603 Pfam PF00152 tRNA synthetases class II (D, K and N) 122 555 1.6E-94 T 29-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMALA_RS20150 da433fc179c151702afb9e848d836bcb 603 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 5 581 1.6E-185 T 29-03-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 SMALA_RS20150 da433fc179c151702afb9e848d836bcb 603 Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. 4 582 30.528 T 29-03-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 SMALA_RS32230 7211c511d52c692dac00cf9b0b9bed20 230 Gene3D G3DSA:3.40.50.880 1 230 1.4E-45 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS32230 7211c511d52c692dac00cf9b0b9bed20 230 Pfam PF07722 Peptidase C26 4 213 1.6E-64 T 29-03-2018 IPR011697 Peptidase C26 GO:0016787 Reactome: R-HSA-6798695 SMALA_RS32230 7211c511d52c692dac00cf9b0b9bed20 230 SUPERFAMILY SSF52317 31 228 1.31E-40 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS36650 c654a2cf64dee007d5148ae7916698c7 290 Gene3D G3DSA:3.10.450.50 149 285 2.4E-23 T 29-03-2018 SMALA_RS36650 c654a2cf64dee007d5148ae7916698c7 290 SUPERFAMILY SSF54427 168 287 3.17E-18 T 29-03-2018 IPR032710 NTF2-like domain SMALA_RS36650 c654a2cf64dee007d5148ae7916698c7 290 Gene3D G3DSA:1.10.1740.10 3 70 1.6E-12 T 29-03-2018 SMALA_RS36650 c654a2cf64dee007d5148ae7916698c7 290 Pfam PF04542 Sigma-70 region 2 8 70 1.9E-13 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS36650 c654a2cf64dee007d5148ae7916698c7 290 Pfam PF12680 SnoaL-like domain 173 269 9.4E-7 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain SMALA_RS36650 c654a2cf64dee007d5148ae7916698c7 290 Pfam PF08281 Sigma-70, region 4 104 154 3.0E-12 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS36650 c654a2cf64dee007d5148ae7916698c7 290 Gene3D G3DSA:1.10.10.10 71 148 1.4E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS36650 c654a2cf64dee007d5148ae7916698c7 290 SUPERFAMILY SSF88946 7 86 5.49E-13 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS36650 c654a2cf64dee007d5148ae7916698c7 290 SUPERFAMILY SSF88659 100 157 3.74E-11 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS36650 c654a2cf64dee007d5148ae7916698c7 290 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 7 157 2.4E-16 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS12960 08edf429ca068fdafb7a9c91a6c6a2a3 240 Gene3D G3DSA:3.60.15.10 2 238 6.4E-28 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS12960 08edf429ca068fdafb7a9c91a6c6a2a3 240 Pfam PF00753 Metallo-beta-lactamase superfamily 29 216 5.3E-12 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS12960 08edf429ca068fdafb7a9c91a6c6a2a3 240 SUPERFAMILY SSF56281 7 234 5.74E-39 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS12960 08edf429ca068fdafb7a9c91a6c6a2a3 240 SMART SM00849 26 216 2.8E-15 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS31445 a55ac8820aa7f59519e49481d9be86b7 298 Gene3D G3DSA:3.40.50.261 124 298 8.8E-49 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMALA_RS31445 a55ac8820aa7f59519e49481d9be86b7 298 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 238 251 - T 29-03-2018 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site SMALA_RS31445 a55ac8820aa7f59519e49481d9be86b7 298 PRINTS PR01798 Succinyl-CoA synthase signature 179 197 6.9E-33 T 29-03-2018 SMALA_RS31445 a55ac8820aa7f59519e49481d9be86b7 298 PRINTS PR01798 Succinyl-CoA synthase signature 86 103 6.9E-33 T 29-03-2018 SMALA_RS31445 a55ac8820aa7f59519e49481d9be86b7 298 PRINTS PR01798 Succinyl-CoA synthase signature 210 223 6.9E-33 T 29-03-2018 SMALA_RS31445 a55ac8820aa7f59519e49481d9be86b7 298 PRINTS PR01798 Succinyl-CoA synthase signature 242 259 6.9E-33 T 29-03-2018 SMALA_RS31445 a55ac8820aa7f59519e49481d9be86b7 298 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 1 290 38.976 T 29-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 SMALA_RS31445 a55ac8820aa7f59519e49481d9be86b7 298 Gene3D G3DSA:3.40.50.720 1 123 2.5E-40 T 29-03-2018 SMALA_RS31445 a55ac8820aa7f59519e49481d9be86b7 298 SUPERFAMILY SSF51735 1 126 2.76E-36 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS31445 a55ac8820aa7f59519e49481d9be86b7 298 Pfam PF00549 CoA-ligase 156 273 1.8E-13 T 29-03-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMALA_RS31445 a55ac8820aa7f59519e49481d9be86b7 298 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 156 183 - T 29-03-2018 IPR033847 ATP-citrate lyase/succinyl-CoA ligase, conserved site SMALA_RS31445 a55ac8820aa7f59519e49481d9be86b7 298 SUPERFAMILY SSF52210 127 289 5.49E-46 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMALA_RS31445 a55ac8820aa7f59519e49481d9be86b7 298 SMART SM00881 4 104 5.4E-27 T 29-03-2018 IPR003781 CoA-binding GO:0048037 SMALA_RS31445 a55ac8820aa7f59519e49481d9be86b7 298 PIRSF PIRSF001553 1 293 1.3E-113 T 29-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 SMALA_RS31445 a55ac8820aa7f59519e49481d9be86b7 298 Pfam PF02629 CoA binding domain 7 103 1.5E-26 T 29-03-2018 IPR003781 CoA-binding GO:0048037 SMALA_RS31445 a55ac8820aa7f59519e49481d9be86b7 298 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 3 290 1.6E-124 T 29-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 SMALA_RS18740 89153f07400de8f1baec3c21fad843d1 425 SUPERFAMILY SSF48264 46 423 2.36E-89 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS18740 89153f07400de8f1baec3c21fad843d1 425 Gene3D G3DSA:1.10.630.10 35 425 6.9E-74 T 29-03-2018 SMALA_RS18740 89153f07400de8f1baec3c21fad843d1 425 Pfam PF00067 Cytochrome P450 235 394 2.3E-20 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS18740 89153f07400de8f1baec3c21fad843d1 425 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 366 375 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMALA_RS18740 89153f07400de8f1baec3c21fad843d1 425 PRINTS PR00385 P450 superfamily signature 373 384 8.2E-7 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS18740 89153f07400de8f1baec3c21fad843d1 425 PRINTS PR00385 P450 superfamily signature 262 279 8.2E-7 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS18740 89153f07400de8f1baec3c21fad843d1 425 PRINTS PR00385 P450 superfamily signature 364 373 8.2E-7 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS18740 89153f07400de8f1baec3c21fad843d1 425 PRINTS PR00385 P450 superfamily signature 297 308 8.2E-7 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS18740 89153f07400de8f1baec3c21fad843d1 425 PRINTS PR00359 B-class P450 signature 181 196 9.6E-54 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS18740 89153f07400de8f1baec3c21fad843d1 425 PRINTS PR00359 B-class P450 signature 373 384 9.6E-54 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS18740 89153f07400de8f1baec3c21fad843d1 425 PRINTS PR00359 B-class P450 signature 364 373 9.6E-54 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS18740 89153f07400de8f1baec3c21fad843d1 425 PRINTS PR00359 B-class P450 signature 117 128 9.6E-54 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS18740 89153f07400de8f1baec3c21fad843d1 425 PRINTS PR00359 B-class P450 signature 164 180 9.6E-54 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS18740 89153f07400de8f1baec3c21fad843d1 425 PRINTS PR00359 B-class P450 signature 297 308 9.6E-54 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS18740 89153f07400de8f1baec3c21fad843d1 425 PRINTS PR00359 B-class P450 signature 315 342 9.6E-54 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS18740 89153f07400de8f1baec3c21fad843d1 425 PRINTS PR00359 B-class P450 signature 343 358 9.6E-54 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS18740 89153f07400de8f1baec3c21fad843d1 425 PRINTS PR00359 B-class P450 signature 218 240 9.6E-54 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS01000 be5e097ce1b3946404832da021830000 472 Pfam PF00069 Protein kinase domain 28 279 2.6E-33 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMALA_RS01000 be5e097ce1b3946404832da021830000 472 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 152 164 - T 29-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMALA_RS01000 be5e097ce1b3946404832da021830000 472 Gene3D G3DSA:1.10.510.10 116 449 3.5E-39 T 29-03-2018 SMALA_RS01000 be5e097ce1b3946404832da021830000 472 Gene3D G3DSA:3.30.200.20 8 115 3.1E-15 T 29-03-2018 SMALA_RS01000 be5e097ce1b3946404832da021830000 472 SMART SM00220 28 283 6.9E-40 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMALA_RS01000 be5e097ce1b3946404832da021830000 472 SUPERFAMILY SSF56112 21 282 9.85E-54 T 29-03-2018 IPR011009 Protein kinase-like domain SMALA_RS07385 f18308080ed03d0b98aabf32554e9ba6 531 Gene3D G3DSA:3.40.50.300 6 239 3.7E-45 T 29-03-2018 SMALA_RS07385 f18308080ed03d0b98aabf32554e9ba6 531 Pfam PF00005 ABC transporter 25 173 4.6E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS07385 f18308080ed03d0b98aabf32554e9ba6 531 Pfam PF00005 ABC transporter 285 434 9.1E-14 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS07385 f18308080ed03d0b98aabf32554e9ba6 531 Gene3D G3DSA:3.40.50.300 268 493 3.7E-30 T 29-03-2018 SMALA_RS07385 f18308080ed03d0b98aabf32554e9ba6 531 SUPERFAMILY SSF52540 284 490 8.04E-34 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS07385 f18308080ed03d0b98aabf32554e9ba6 531 ProSitePatterns PS00211 ABC transporters family signature. 411 425 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS07385 f18308080ed03d0b98aabf32554e9ba6 531 SMART SM00382 34 229 2.9E-6 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS07385 f18308080ed03d0b98aabf32554e9ba6 531 SUPERFAMILY SSF52540 9 233 4.41E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS02345 876fa0c90c649e9d0f95d8dcedc51bdd 2847 SUPERFAMILY SSF47336 953 1068 1.44E-19 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS02345 876fa0c90c649e9d0f95d8dcedc51bdd 2847 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2422 2602 8.0E-58 T 29-03-2018 SMALA_RS02345 876fa0c90c649e9d0f95d8dcedc51bdd 2847 SUPERFAMILY SSF52151 1582 1713 8.89E-68 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS02345 876fa0c90c649e9d0f95d8dcedc51bdd 2847 SUPERFAMILY SSF52151 1774 1870 8.89E-68 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS02345 876fa0c90c649e9d0f95d8dcedc51bdd 2847 SMART SM00823 Phosphopantetheine attachment site 958 1030 5.0E-26 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS02345 876fa0c90c649e9d0f95d8dcedc51bdd 2847 SMART SM00823 Phosphopantetheine attachment site 2707 2779 3.9E-23 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS02345 876fa0c90c649e9d0f95d8dcedc51bdd 2847 Gene3D G3DSA:3.40.50.720 2419 2680 3.6E-49 T 29-03-2018 SMALA_RS02345 876fa0c90c649e9d0f95d8dcedc51bdd 2847 Gene3D G3DSA:1.10.1200.10 2700 2837 1.1E-19 T 29-03-2018 SMALA_RS02345 876fa0c90c649e9d0f95d8dcedc51bdd 2847 Gene3D G3DSA:1.10.1200.10 951 1052 2.1E-16 T 29-03-2018 SMALA_RS02345 876fa0c90c649e9d0f95d8dcedc51bdd 2847 SUPERFAMILY SSF47336 2700 2798 1.3E-17 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS02345 876fa0c90c649e9d0f95d8dcedc51bdd 2847 Pfam PF00550 Phosphopantetheine attachment site 960 1025 1.2E-7 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS02345 876fa0c90c649e9d0f95d8dcedc51bdd 2847 Pfam PF00550 Phosphopantetheine attachment site 2710 2774 7.5E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS02345 876fa0c90c649e9d0f95d8dcedc51bdd 2847 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 565 864 4.9E-108 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS02345 876fa0c90c649e9d0f95d8dcedc51bdd 2847 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1585 1884 1.7E-112 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS02345 876fa0c90c649e9d0f95d8dcedc51bdd 2847 SUPERFAMILY SSF53901 34 406 1.05E-102 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS02345 876fa0c90c649e9d0f95d8dcedc51bdd 2847 Pfam PF08659 KR domain 2422 2600 3.0E-58 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS02345 876fa0c90c649e9d0f95d8dcedc51bdd 2847 Gene3D G3DSA:3.40.47.10 28 296 2.6E-84 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS02345 876fa0c90c649e9d0f95d8dcedc51bdd 2847 Gene3D G3DSA:3.40.47.10 1053 1315 4.0E-81 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS02345 876fa0c90c649e9d0f95d8dcedc51bdd 2847 Gene3D G3DSA:3.10.129.10 1956 2076 1.1E-7 T 29-03-2018 SMALA_RS02345 876fa0c90c649e9d0f95d8dcedc51bdd 2847 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1429 1549 1.1E-13 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS02345 876fa0c90c649e9d0f95d8dcedc51bdd 2847 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 412 509 1.6E-10 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS02345 876fa0c90c649e9d0f95d8dcedc51bdd 2847 Pfam PF00698 Acyl transferase domain 1585 1902 1.8E-52 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS02345 876fa0c90c649e9d0f95d8dcedc51bdd 2847 Pfam PF00698 Acyl transferase domain 564 882 5.2E-81 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS02345 876fa0c90c649e9d0f95d8dcedc51bdd 2847 Gene3D G3DSA:3.30.70.250 698 747 1.3E-14 T 29-03-2018 SMALA_RS02345 876fa0c90c649e9d0f95d8dcedc51bdd 2847 Gene3D G3DSA:3.30.70.250 1722 1764 4.3E-17 T 29-03-2018 SMALA_RS02345 876fa0c90c649e9d0f95d8dcedc51bdd 2847 Gene3D G3DSA:3.40.366.10 561 697 1.8E-37 T 29-03-2018 SMALA_RS02345 876fa0c90c649e9d0f95d8dcedc51bdd 2847 Gene3D G3DSA:3.40.366.10 1582 1721 1.1E-37 T 29-03-2018 SMALA_RS02345 876fa0c90c649e9d0f95d8dcedc51bdd 2847 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1053 1303 2.0E-87 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS02345 876fa0c90c649e9d0f95d8dcedc51bdd 2847 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 35 284 8.6E-91 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS02345 876fa0c90c649e9d0f95d8dcedc51bdd 2847 SUPERFAMILY SSF51735 2420 2657 3.28E-47 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS02345 876fa0c90c649e9d0f95d8dcedc51bdd 2847 Pfam PF14765 Polyketide synthase dehydratase 1954 2234 2.9E-53 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS02345 876fa0c90c649e9d0f95d8dcedc51bdd 2847 SMART SM01294 2708 2775 9.6E-5 T 29-03-2018 SMALA_RS02345 876fa0c90c649e9d0f95d8dcedc51bdd 2847 SUPERFAMILY SSF53901 1051 1424 3.28E-101 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS02345 876fa0c90c649e9d0f95d8dcedc51bdd 2847 SMART SM00826 1954 2123 8.1E-71 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS02345 876fa0c90c649e9d0f95d8dcedc51bdd 2847 SUPERFAMILY SSF52151 755 847 1.1E-62 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS02345 876fa0c90c649e9d0f95d8dcedc51bdd 2847 SUPERFAMILY SSF52151 561 690 1.1E-62 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS02345 876fa0c90c649e9d0f95d8dcedc51bdd 2847 SUPERFAMILY SSF51735 2241 2406 2.25E-26 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS02345 876fa0c90c649e9d0f95d8dcedc51bdd 2847 SMART SM00825 Beta-ketoacyl synthase 37 462 1.9E-222 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS02345 876fa0c90c649e9d0f95d8dcedc51bdd 2847 SMART SM00825 Beta-ketoacyl synthase 1055 1479 1.5E-218 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS02345 876fa0c90c649e9d0f95d8dcedc51bdd 2847 SUPERFAMILY SSF55048 1712 1773 1.96E-10 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS02345 876fa0c90c649e9d0f95d8dcedc51bdd 2847 Gene3D G3DSA:3.40.366.10 1765 1886 1.4E-27 T 29-03-2018 SMALA_RS02345 876fa0c90c649e9d0f95d8dcedc51bdd 2847 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1216 1232 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS02345 876fa0c90c649e9d0f95d8dcedc51bdd 2847 Gene3D G3DSA:3.40.366.10 748 870 2.9E-21 T 29-03-2018 SMALA_RS02345 876fa0c90c649e9d0f95d8dcedc51bdd 2847 SUPERFAMILY SSF55048 689 754 1.29E-11 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS02345 876fa0c90c649e9d0f95d8dcedc51bdd 2847 Gene3D G3DSA:3.40.47.10 299 460 4.6E-60 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS02345 876fa0c90c649e9d0f95d8dcedc51bdd 2847 Gene3D G3DSA:3.40.47.10 1318 1477 4.5E-62 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS02345 876fa0c90c649e9d0f95d8dcedc51bdd 2847 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 292 409 5.7E-43 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS02345 876fa0c90c649e9d0f95d8dcedc51bdd 2847 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1311 1426 1.7E-44 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS02345 876fa0c90c649e9d0f95d8dcedc51bdd 2847 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2734 2749 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS02345 876fa0c90c649e9d0f95d8dcedc51bdd 2847 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 197 213 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS09930 481ce0913b5f522b57b67941804a9a5d 486 Gene3D G3DSA:3.40.50.720 145 241 6.8E-23 T 29-03-2018 SMALA_RS09930 481ce0913b5f522b57b67941804a9a5d 486 Gene3D G3DSA:3.50.50.60 242 327 1.3E-28 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS09930 481ce0913b5f522b57b67941804a9a5d 486 Gene3D G3DSA:3.50.50.60 338 464 3.3E-15 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS09930 481ce0913b5f522b57b67941804a9a5d 486 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 40 130 1.9E-20 T 29-03-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 SMALA_RS09930 481ce0913b5f522b57b67941804a9a5d 486 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 146 456 1.7E-33 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS09930 481ce0913b5f522b57b67941804a9a5d 486 SUPERFAMILY SSF46548 6 155 3.14E-36 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 SMALA_RS09930 481ce0913b5f522b57b67941804a9a5d 486 Gene3D G3DSA:1.10.1060.10 5 144 2.0E-38 T 29-03-2018 SMALA_RS09930 481ce0913b5f522b57b67941804a9a5d 486 SUPERFAMILY SSF51971 144 400 5.89E-66 T 29-03-2018 SMALA_RS09930 481ce0913b5f522b57b67941804a9a5d 486 PRINTS PR00419 Adrenodoxin reductase family signature 285 299 8.2E-25 T 29-03-2018 SMALA_RS09930 481ce0913b5f522b57b67941804a9a5d 486 PRINTS PR00419 Adrenodoxin reductase family signature 146 168 8.2E-25 T 29-03-2018 SMALA_RS09930 481ce0913b5f522b57b67941804a9a5d 486 PRINTS PR00419 Adrenodoxin reductase family signature 169 182 8.2E-25 T 29-03-2018 SMALA_RS09930 481ce0913b5f522b57b67941804a9a5d 486 PRINTS PR00419 Adrenodoxin reductase family signature 211 221 8.2E-25 T 29-03-2018 SMALA_RS09930 481ce0913b5f522b57b67941804a9a5d 486 TIGRFAM TIGR01317 GOGAT_sm_gam: glutamate synthase, NADH/NADPH, small subunit 3 474 9.2E-212 T 29-03-2018 IPR006005 Glutamate synthase, NADH/NADPH, small subunit 1 GO:0006537|GO:0016639|GO:0055114 SMALA_RS09175 acc7ac205ecd487987f5fa7ad666266a 327 Pfam PF03186 CobD/Cbib protein 13 293 1.9E-88 T 29-03-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 SMALA_RS09175 acc7ac205ecd487987f5fa7ad666266a 327 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 315 95.155 T 29-03-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 SMALA_RS09175 acc7ac205ecd487987f5fa7ad666266a 327 TIGRFAM TIGR00380 cobD: cobalamin biosynthesis protein CobD 18 298 2.6E-51 T 29-03-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 SMALA_RS32735 5a0f4126846c1472b71b3e86c23c2289 569 Pfam PF08388 Group II intron, maturase-specific domain 343 421 2.1E-20 T 29-03-2018 IPR013597 Group II intron, maturase-specific SMALA_RS32735 5a0f4126846c1472b71b3e86c23c2289 569 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 55 406 8.9E-96 T 29-03-2018 IPR030931 Group II intron reverse transcriptase/maturase SMALA_RS32735 5a0f4126846c1472b71b3e86c23c2289 569 Gene3D G3DSA:3.30.70.270 148 327 3.7E-26 T 29-03-2018 SMALA_RS32735 5a0f4126846c1472b71b3e86c23c2289 569 Pfam PF13655 N-terminal domain of reverse transcriptase 12 93 2.8E-26 T 29-03-2018 IPR025960 Reverse transcriptase, N-terminal domain SMALA_RS32735 5a0f4126846c1472b71b3e86c23c2289 569 SUPERFAMILY SSF56672 99 411 1.39E-45 T 29-03-2018 SMALA_RS32735 5a0f4126846c1472b71b3e86c23c2289 569 Pfam PF01844 HNH endonuclease 527 561 1.2E-6 T 29-03-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 SMALA_RS32735 5a0f4126846c1472b71b3e86c23c2289 569 Gene3D G3DSA:3.40.1800.10 473 568 1.0E-9 T 29-03-2018 SMALA_RS32735 5a0f4126846c1472b71b3e86c23c2289 569 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 110 327 2.7E-39 T 29-03-2018 IPR000477 Reverse transcriptase domain SMALA_RS17265 5a0f4126846c1472b71b3e86c23c2289 569 Pfam PF08388 Group II intron, maturase-specific domain 343 421 2.1E-20 T 29-03-2018 IPR013597 Group II intron, maturase-specific SMALA_RS17265 5a0f4126846c1472b71b3e86c23c2289 569 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 55 406 8.9E-96 T 29-03-2018 IPR030931 Group II intron reverse transcriptase/maturase SMALA_RS17265 5a0f4126846c1472b71b3e86c23c2289 569 Gene3D G3DSA:3.30.70.270 148 327 3.7E-26 T 29-03-2018 SMALA_RS17265 5a0f4126846c1472b71b3e86c23c2289 569 Pfam PF13655 N-terminal domain of reverse transcriptase 12 93 2.8E-26 T 29-03-2018 IPR025960 Reverse transcriptase, N-terminal domain SMALA_RS17265 5a0f4126846c1472b71b3e86c23c2289 569 SUPERFAMILY SSF56672 99 411 1.39E-45 T 29-03-2018 SMALA_RS17265 5a0f4126846c1472b71b3e86c23c2289 569 Pfam PF01844 HNH endonuclease 527 561 1.2E-6 T 29-03-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 SMALA_RS17265 5a0f4126846c1472b71b3e86c23c2289 569 Gene3D G3DSA:3.40.1800.10 473 568 1.0E-9 T 29-03-2018 SMALA_RS17265 5a0f4126846c1472b71b3e86c23c2289 569 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 110 327 2.7E-39 T 29-03-2018 IPR000477 Reverse transcriptase domain SMALA_RS27955 16bc1a2f60d020a07ec73e2a6eb102b8 390 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 132 143 - T 29-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMALA_RS27955 16bc1a2f60d020a07ec73e2a6eb102b8 390 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 325 353 - T 29-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMALA_RS27955 16bc1a2f60d020a07ec73e2a6eb102b8 390 Gene3D G3DSA:3.40.50.20 13 175 7.4E-47 T 29-03-2018 SMALA_RS27955 16bc1a2f60d020a07ec73e2a6eb102b8 390 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 23 382 1.3E-106 T 29-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMALA_RS27955 16bc1a2f60d020a07ec73e2a6eb102b8 390 SUPERFAMILY SSF52440 21 164 2.78E-35 T 29-03-2018 IPR016185 Pre-ATP-grasp domain SMALA_RS27955 16bc1a2f60d020a07ec73e2a6eb102b8 390 Gene3D G3DSA:3.30.1490.20 184 241 5.1E-24 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SMALA_RS27955 16bc1a2f60d020a07ec73e2a6eb102b8 390 SUPERFAMILY SSF56059 165 384 4.65E-54 T 29-03-2018 SMALA_RS27955 16bc1a2f60d020a07ec73e2a6eb102b8 390 Pfam PF07478 D-ala D-ala ligase C-terminus 174 380 9.4E-68 T 29-03-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMALA_RS27955 16bc1a2f60d020a07ec73e2a6eb102b8 390 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 22 383 42.055 T 29-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMALA_RS27955 16bc1a2f60d020a07ec73e2a6eb102b8 390 Gene3D G3DSA:3.30.470.20 242 389 4.3E-40 T 29-03-2018 SMALA_RS27955 16bc1a2f60d020a07ec73e2a6eb102b8 390 Pfam PF01820 D-ala D-ala ligase N-terminus 23 154 2.4E-31 T 29-03-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMALA_RS27955 16bc1a2f60d020a07ec73e2a6eb102b8 390 PIRSF PIRSF039102 19 389 2.2E-112 T 29-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMALA_RS37850 945741ec3689961e6a121284c95890bc 2109 SMART SM00823 Phosphopantetheine attachment site 1725 1797 4.2E-26 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37850 945741ec3689961e6a121284c95890bc 2109 Gene3D G3DSA:3.40.366.10 765 879 5.9E-26 T 29-03-2018 SMALA_RS37850 945741ec3689961e6a121284c95890bc 2109 Pfam PF00975 Thioesterase domain 1902 2105 4.7E-13 T 29-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 SMALA_RS37850 945741ec3689961e6a121284c95890bc 2109 SUPERFAMILY SSF101173 2 33 2.09E-5 T 29-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 SMALA_RS37850 945741ec3689961e6a121284c95890bc 2109 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1437 1617 1.3E-54 T 29-03-2018 SMALA_RS37850 945741ec3689961e6a121284c95890bc 2109 Pfam PF00698 Acyl transferase domain 578 895 3.1E-91 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS37850 945741ec3689961e6a121284c95890bc 2109 Gene3D G3DSA:3.10.129.10 946 1065 2.9E-9 T 29-03-2018 SMALA_RS37850 945741ec3689961e6a121284c95890bc 2109 Gene3D G3DSA:3.40.47.10 297 458 1.2E-63 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS37850 945741ec3689961e6a121284c95890bc 2109 SUPERFAMILY SSF53474 1755 1793 1.04E-34 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS37850 945741ec3689961e6a121284c95890bc 2109 SUPERFAMILY SSF53474 1871 2107 1.04E-34 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS37850 945741ec3689961e6a121284c95890bc 2109 Gene3D G3DSA:3.40.366.10 575 716 6.4E-43 T 29-03-2018 SMALA_RS37850 945741ec3689961e6a121284c95890bc 2109 Pfam PF00550 Phosphopantetheine attachment site 1727 1793 3.4E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS37850 945741ec3689961e6a121284c95890bc 2109 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 195 211 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS37850 945741ec3689961e6a121284c95890bc 2109 SUPERFAMILY SSF55048 703 768 1.44E-14 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS37850 945741ec3689961e6a121284c95890bc 2109 Gene3D G3DSA:3.30.70.250 717 764 3.7E-20 T 29-03-2018 SMALA_RS37850 945741ec3689961e6a121284c95890bc 2109 SMART SM00826 944 1111 1.3E-78 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37850 945741ec3689961e6a121284c95890bc 2109 Pfam PF14765 Polyketide synthase dehydratase 944 1229 3.4E-54 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37850 945741ec3689961e6a121284c95890bc 2109 Gene3D G3DSA:1.10.1200.10 1731 1839 4.4E-20 T 29-03-2018 SMALA_RS37850 945741ec3689961e6a121284c95890bc 2109 SUPERFAMILY SSF52151 575 704 1.23E-67 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS37850 945741ec3689961e6a121284c95890bc 2109 SUPERFAMILY SSF52151 769 867 1.23E-67 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS37850 945741ec3689961e6a121284c95890bc 2109 SMART SM00824 Thioesterase 1896 2106 1.4E-101 T 29-03-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 SMALA_RS37850 945741ec3689961e6a121284c95890bc 2109 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 290 407 1.8E-45 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS37850 945741ec3689961e6a121284c95890bc 2109 SMART SM00825 Beta-ketoacyl synthase 35 460 4.3E-214 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS37850 945741ec3689961e6a121284c95890bc 2109 Gene3D G3DSA:3.40.50.720 1413 1730 2.3E-40 T 29-03-2018 SMALA_RS37850 945741ec3689961e6a121284c95890bc 2109 Pfam PF08659 KR domain 1437 1615 3.1E-57 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37850 945741ec3689961e6a121284c95890bc 2109 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 410 508 9.4E-10 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37850 945741ec3689961e6a121284c95890bc 2109 SUPERFAMILY SSF53901 29 405 1.63E-105 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS37850 945741ec3689961e6a121284c95890bc 2109 Pfam PF08990 Erythronolide synthase docking 3 26 2.7E-11 T 29-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 SMALA_RS37850 945741ec3689961e6a121284c95890bc 2109 SUPERFAMILY SSF51735 1235 1421 3.82E-33 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS37850 945741ec3689961e6a121284c95890bc 2109 SUPERFAMILY SSF51735 1437 1631 1.06E-40 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS37850 945741ec3689961e6a121284c95890bc 2109 Gene3D G3DSA:3.40.50.1820 1840 2109 9.5E-23 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS37850 945741ec3689961e6a121284c95890bc 2109 Gene3D G3DSA:3.40.47.10 25 293 1.5E-84 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS37850 945741ec3689961e6a121284c95890bc 2109 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 579 877 1.9E-125 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS37850 945741ec3689961e6a121284c95890bc 2109 SMART SM01294 1725 1793 4.2E-4 T 29-03-2018 SMALA_RS37850 945741ec3689961e6a121284c95890bc 2109 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 33 282 1.6E-86 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS12360 528d5c5aab3875f3b1d4b6a306c61473 662 Gene3D G3DSA:3.40.1360.10 243 371 1.3E-30 T 29-03-2018 SMALA_RS12360 528d5c5aab3875f3b1d4b6a306c61473 662 SUPERFAMILY SSF56731 117 428 9.42E-95 T 29-03-2018 SMALA_RS12360 528d5c5aab3875f3b1d4b6a306c61473 662 TIGRFAM TIGR01391 dnaG: DNA primase 5 416 1.4E-116 T 29-03-2018 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 SMALA_RS12360 528d5c5aab3875f3b1d4b6a306c61473 662 Hamap MF_00974 DNA primase [dnaG]. 4 646 26.106 T 29-03-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 SMALA_RS12360 528d5c5aab3875f3b1d4b6a306c61473 662 Gene3D G3DSA:3.90.980.10 110 242 1.2E-43 T 29-03-2018 IPR013264 DNA primase, catalytic core, N-terminal SMALA_RS12360 528d5c5aab3875f3b1d4b6a306c61473 662 Gene3D G3DSA:3.90.580.10 1 103 1.8E-32 T 29-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 SMALA_RS12360 528d5c5aab3875f3b1d4b6a306c61473 662 Pfam PF08278 DNA primase DnaG DnaB-binding 515 633 1.2E-13 T 29-03-2018 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 SMALA_RS12360 528d5c5aab3875f3b1d4b6a306c61473 662 Pfam PF08275 DNA primase catalytic core, N-terminal domain 127 253 5.1E-37 T 29-03-2018 IPR013264 DNA primase, catalytic core, N-terminal SMALA_RS12360 528d5c5aab3875f3b1d4b6a306c61473 662 SMART SM00766 514 641 2.9E-11 T 29-03-2018 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 SMALA_RS12360 528d5c5aab3875f3b1d4b6a306c61473 662 Pfam PF13662 Toprim domain 262 332 4.9E-16 T 29-03-2018 IPR006171 TOPRIM domain SMALA_RS12360 528d5c5aab3875f3b1d4b6a306c61473 662 Pfam PF10410 DnaB-helicase binding domain of primase 373 425 7.9E-14 T 29-03-2018 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 SMALA_RS12360 528d5c5aab3875f3b1d4b6a306c61473 662 Gene3D G3DSA:1.10.860.10 500 651 1.5E-14 T 29-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal SMALA_RS12360 528d5c5aab3875f3b1d4b6a306c61473 662 SMART SM00493 261 337 1.8E-14 T 29-03-2018 IPR006171 TOPRIM domain SMALA_RS12360 528d5c5aab3875f3b1d4b6a306c61473 662 Pfam PF01807 CHC2 zinc finger 7 101 1.7E-31 T 29-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 SMALA_RS12360 528d5c5aab3875f3b1d4b6a306c61473 662 SUPERFAMILY SSF57783 4 102 3.57E-31 T 29-03-2018 SMALA_RS12360 528d5c5aab3875f3b1d4b6a306c61473 662 SMART SM00400 37 91 3.9E-32 T 29-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 SMALA_RS12360 528d5c5aab3875f3b1d4b6a306c61473 662 Gene3D G3DSA:1.20.50.20 372 425 6.0E-14 T 29-03-2018 SMALA_RS12360 528d5c5aab3875f3b1d4b6a306c61473 662 PIRSF PIRSF002811 2 652 3.1E-162 T 29-03-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 SMALA_RS19705 234ad26e4b09e874e4efa02a176f231f 127 Pfam PF00825 Ribonuclease P 2 121 2.2E-27 T 29-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 SMALA_RS19705 234ad26e4b09e874e4efa02a176f231f 127 ProSitePatterns PS00648 Bacterial ribonuclease P protein component signature. 64 78 - T 29-03-2018 IPR020539 Ribonuclease P, conserved site GO:0004526 SMALA_RS19705 234ad26e4b09e874e4efa02a176f231f 127 ProDom PD003629 P RIBONUCLEASE COMPONENT HYDROLASE RNASE C5 RNASEP RNA-BINDING PROCESSING ENDONUCLEASE 49 114 7.0E-5 T 29-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 SMALA_RS19705 234ad26e4b09e874e4efa02a176f231f 127 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 2 124 16.519 T 29-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 SMALA_RS19705 234ad26e4b09e874e4efa02a176f231f 127 Gene3D G3DSA:3.30.230.10 1 123 9.3E-31 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SMALA_RS19705 234ad26e4b09e874e4efa02a176f231f 127 SUPERFAMILY SSF54211 2 122 1.77E-23 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SMALA_RS19705 234ad26e4b09e874e4efa02a176f231f 127 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 4 101 2.3E-16 T 29-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 SMALA_RS09005 36bb27e550949068ea32370e403345cf 471 SUPERFAMILY SSF52374 47 364 5.09E-75 T 29-03-2018 SMALA_RS09005 36bb27e550949068ea32370e403345cf 471 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 88 98 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMALA_RS09005 36bb27e550949068ea32370e403345cf 471 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 257 269 2.5E-21 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 SMALA_RS09005 36bb27e550949068ea32370e403345cf 471 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 92 114 2.5E-21 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 SMALA_RS09005 36bb27e550949068ea32370e403345cf 471 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 207 222 2.5E-21 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 SMALA_RS09005 36bb27e550949068ea32370e403345cf 471 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 224 246 2.5E-21 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 SMALA_RS09005 36bb27e550949068ea32370e403345cf 471 Gene3D G3DSA:1.10.240.10 267 368 3.7E-19 T 29-03-2018 SMALA_RS09005 36bb27e550949068ea32370e403345cf 471 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 50 417 1.1E-86 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 SMALA_RS09005 36bb27e550949068ea32370e403345cf 471 Pfam PF00579 tRNA synthetases class I (W and Y) 80 360 1.3E-55 T 29-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMALA_RS09005 36bb27e550949068ea32370e403345cf 471 Gene3D G3DSA:3.40.50.620 40 264 9.0E-50 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS01380 ec5673f4762110bf64505266682979db 71 SUPERFAMILY SSF54862 4 62 6.36E-7 T 29-03-2018 SMALA_RS01380 ec5673f4762110bf64505266682979db 71 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 7 59 3.8E-10 T 29-03-2018 SMALA_RS01380 ec5673f4762110bf64505266682979db 71 Gene3D G3DSA:3.30.70.20 2 63 1.8E-4 T 29-03-2018 SMALA_RS01380 ec5673f4762110bf64505266682979db 71 PRINTS PR00352 3Fe-4S ferredoxin signature 46 58 4.1E-5 T 29-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 SMALA_RS01380 ec5673f4762110bf64505266682979db 71 PRINTS PR00352 3Fe-4S ferredoxin signature 18 28 4.1E-5 T 29-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 SMALA_RS01380 ec5673f4762110bf64505266682979db 71 PRINTS PR00352 3Fe-4S ferredoxin signature 7 18 4.1E-5 T 29-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 SMALA_RS41180 3a65731a8159df3f23a5e0d599f1a681 524 Pfam PF01297 Zinc-uptake complex component A periplasmic 43 518 3.3E-76 T 29-03-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 SMALA_RS41180 3a65731a8159df3f23a5e0d599f1a681 524 PRINTS PR00690 Adhesin family signature 40 58 5.3E-10 T 29-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 SMALA_RS41180 3a65731a8159df3f23a5e0d599f1a681 524 PRINTS PR00690 Adhesin family signature 84 101 5.3E-10 T 29-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 SMALA_RS41180 3a65731a8159df3f23a5e0d599f1a681 524 PRINTS PR00690 Adhesin family signature 71 84 5.3E-10 T 29-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 SMALA_RS41180 3a65731a8159df3f23a5e0d599f1a681 524 SUPERFAMILY SSF53807 38 131 3.57E-68 T 29-03-2018 SMALA_RS41180 3a65731a8159df3f23a5e0d599f1a681 524 SUPERFAMILY SSF53807 342 521 3.57E-68 T 29-03-2018 SMALA_RS41180 3a65731a8159df3f23a5e0d599f1a681 524 Gene3D G3DSA:3.40.50.1980 30 400 4.0E-49 T 29-03-2018 SMALA_RS41180 3a65731a8159df3f23a5e0d599f1a681 524 PRINTS PR00691 Adhesin B signature 65 83 2.2E-13 T 29-03-2018 IPR006129 Adhesin B GO:0007155 SMALA_RS41180 3a65731a8159df3f23a5e0d599f1a681 524 PRINTS PR00691 Adhesin B signature 40 61 2.2E-13 T 29-03-2018 IPR006129 Adhesin B GO:0007155 SMALA_RS41180 3a65731a8159df3f23a5e0d599f1a681 524 PRINTS PR00691 Adhesin B signature 84 103 2.2E-13 T 29-03-2018 IPR006129 Adhesin B GO:0007155 SMALA_RS41180 3a65731a8159df3f23a5e0d599f1a681 524 Gene3D G3DSA:3.40.50.1980 401 520 9.4E-32 T 29-03-2018 SMALA_RS41180 3a65731a8159df3f23a5e0d599f1a681 524 TIGRFAM TIGR03769 P_ac_wall_RPT: actinobacterial surface-anchored protein domain 212 254 2.8E-13 T 29-03-2018 IPR022435 Surface-anchored repeat, actinobacteria SMALA_RS41180 3a65731a8159df3f23a5e0d599f1a681 524 TIGRFAM TIGR03772 anch_rpt_subst: anchored repeat ABC transporter, substrate-binding protein 43 520 1.3E-200 T 29-03-2018 IPR022434 ABC transporter, LPXTG-anchor lipoprotein, actinobacteria SMALA_RS19170 cba16529a3055bf503b6d75f6db73b7d 149 ProDom PD004028 INHIBITOR PROTEASE SERINE DIRECT SEQUENCING SUBTILISIN PRECURSOR SIGNAL INHIBITOR-LIKE INHIBITOR 60 135 3.0E-10 T 29-03-2018 IPR023549 Subtilisin inhibitor GO:0004867 SMALA_RS19170 cba16529a3055bf503b6d75f6db73b7d 149 Pfam PF00720 Subtilisin inhibitor-like 43 123 5.1E-14 T 29-03-2018 IPR023549 Subtilisin inhibitor GO:0004867 SMALA_RS19170 cba16529a3055bf503b6d75f6db73b7d 149 Gene3D G3DSA:3.30.350.10 40 142 3.1E-32 T 29-03-2018 IPR023549 Subtilisin inhibitor GO:0004867 SMALA_RS19170 cba16529a3055bf503b6d75f6db73b7d 149 SUPERFAMILY SSF55399 43 141 9.42E-27 T 29-03-2018 IPR023549 Subtilisin inhibitor GO:0004867 SMALA_RS19170 cba16529a3055bf503b6d75f6db73b7d 149 ProSitePatterns PS00999 Streptomyces subtilisin-type inhibitors signature. 64 81 - T 29-03-2018 IPR020054 Proteinase inhibitor I16, Streptomyces subtilisin-type inhibitor, conserved site GO:0004867 SMALA_RS34120 69d005038fae600600824901b1ef096f 535 SUPERFAMILY SSF53850 42 321 7.85E-13 T 29-03-2018 SMALA_RS34120 69d005038fae600600824901b1ef096f 535 Gene3D G3DSA:3.40.190.10 16 321 1.3E-8 T 29-03-2018 SMALA_RS34120 69d005038fae600600824901b1ef096f 535 Pfam PF00092 von Willebrand factor type A domain 349 514 1.0E-8 T 29-03-2018 IPR002035 von Willebrand factor, type A SMALA_RS34120 69d005038fae600600824901b1ef096f 535 Pfam PF13531 Bacterial extracellular solute-binding protein 44 297 2.3E-23 T 29-03-2018 SMALA_RS34120 69d005038fae600600824901b1ef096f 535 Gene3D G3DSA:3.40.50.410 345 534 1.5E-21 T 29-03-2018 IPR002035 von Willebrand factor, type A SMALA_RS34120 69d005038fae600600824901b1ef096f 535 SMART SM00327 346 531 4.8E-7 T 29-03-2018 IPR002035 von Willebrand factor, type A SMALA_RS34120 69d005038fae600600824901b1ef096f 535 SUPERFAMILY SSF53300 348 532 4.01E-17 T 29-03-2018 IPR002035 von Willebrand factor, type A SMALA_RS28680 a84641696969f0428b908e8b857f5d8b 299 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 10 294 57.7 T 29-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMALA_RS28680 a84641696969f0428b908e8b857f5d8b 299 SMART SM01130 10 295 1.1E-122 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SMALA_RS28680 a84641696969f0428b908e8b857f5d8b 299 SUPERFAMILY SSF51569 8 294 2.41E-96 T 29-03-2018 SMALA_RS28680 a84641696969f0428b908e8b857f5d8b 299 Gene3D G3DSA:3.20.20.70 5 298 1.6E-95 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS28680 a84641696969f0428b908e8b857f5d8b 299 PIRSF PIRSF001365 6 298 1.0E-82 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SMALA_RS28680 a84641696969f0428b908e8b857f5d8b 299 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 47 64 - T 29-03-2018 IPR020624 Schiff base-forming aldolase, conserved site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMALA_RS28680 a84641696969f0428b908e8b857f5d8b 299 PRINTS PR00146 Dihydrodipicolinate synthase signature 80 98 1.6E-31 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SMALA_RS28680 a84641696969f0428b908e8b857f5d8b 299 PRINTS PR00146 Dihydrodipicolinate synthase signature 112 128 1.6E-31 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SMALA_RS28680 a84641696969f0428b908e8b857f5d8b 299 PRINTS PR00146 Dihydrodipicolinate synthase signature 137 154 1.6E-31 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SMALA_RS28680 a84641696969f0428b908e8b857f5d8b 299 PRINTS PR00146 Dihydrodipicolinate synthase signature 44 65 1.6E-31 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SMALA_RS28680 a84641696969f0428b908e8b857f5d8b 299 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 142 172 - T 29-03-2018 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 SMALA_RS28680 a84641696969f0428b908e8b857f5d8b 299 Pfam PF00701 Dihydrodipicolinate synthetase family 11 293 3.7E-86 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SMALA_RS28680 a84641696969f0428b908e8b857f5d8b 299 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 14 290 4.8E-87 T 29-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMALA_RS35450 63899abcd6f8ffd19fea6b660c053fc3 291 Gene3D G3DSA:1.10.3720.10 24 281 1.1E-31 T 29-03-2018 SMALA_RS35450 63899abcd6f8ffd19fea6b660c053fc3 291 SUPERFAMILY SSF161098 17 291 1.5E-53 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS35450 63899abcd6f8ffd19fea6b660c053fc3 291 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 104 266 3.1E-11 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS03485 82d19453d8cadbbce65fa726ea406ecd 142 SMART SM00960 20 110 2.1E-26 T 29-03-2018 IPR004942 Roadblock/LAMTOR2 domain SMALA_RS03485 82d19453d8cadbbce65fa726ea406ecd 142 Gene3D G3DSA:3.30.450.30 15 142 1.1E-39 T 29-03-2018 SMALA_RS03485 82d19453d8cadbbce65fa726ea406ecd 142 Pfam PF03259 Roadblock/LC7 domain 20 110 1.1E-23 T 29-03-2018 IPR004942 Roadblock/LAMTOR2 domain SMALA_RS03485 82d19453d8cadbbce65fa726ea406ecd 142 SUPERFAMILY SSF103196 14 139 3.84E-34 T 29-03-2018 SMALA_RS31550 3dbd992f1faffedce26556821ddde365 469 PRINTS PR00149 Fumarate lyase superfamily signature 150 168 6.7E-20 T 29-03-2018 IPR000362 Fumarate lyase family SMALA_RS31550 3dbd992f1faffedce26556821ddde365 469 PRINTS PR00149 Fumarate lyase superfamily signature 105 123 6.7E-20 T 29-03-2018 IPR000362 Fumarate lyase family SMALA_RS31550 3dbd992f1faffedce26556821ddde365 469 PRINTS PR00149 Fumarate lyase superfamily signature 235 262 6.7E-20 T 29-03-2018 IPR000362 Fumarate lyase family SMALA_RS31550 3dbd992f1faffedce26556821ddde365 469 PRINTS PR00149 Fumarate lyase superfamily signature 280 296 6.7E-20 T 29-03-2018 IPR000362 Fumarate lyase family SMALA_RS31550 3dbd992f1faffedce26556821ddde365 469 Pfam PF00206 Lyase 26 303 3.9E-41 T 29-03-2018 IPR022761 Fumarate lyase, N-terminal SMALA_RS31550 3dbd992f1faffedce26556821ddde365 469 Gene3D G3DSA:1.20.200.10 108 374 7.2E-67 T 29-03-2018 SMALA_RS31550 3dbd992f1faffedce26556821ddde365 469 Pfam PF10397 Adenylosuccinate lyase C-terminus 369 439 1.0E-7 T 29-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SMALA_RS31550 3dbd992f1faffedce26556821ddde365 469 Gene3D G3DSA:1.10.40.30 375 445 8.2E-14 T 29-03-2018 SMALA_RS31550 3dbd992f1faffedce26556821ddde365 469 SMART SM00998 368 446 7.7E-4 T 29-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SMALA_RS31550 3dbd992f1faffedce26556821ddde365 469 SUPERFAMILY SSF48557 19 451 1.3E-94 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 SMALA_RS31550 3dbd992f1faffedce26556821ddde365 469 Gene3D G3DSA:1.10.275.10 9 107 1.2E-11 T 29-03-2018 IPR024083 Fumarase/histidase, N-terminal SMALA_RS31550 3dbd992f1faffedce26556821ddde365 469 PRINTS PR00145 Argininosuccinate lyase family signature 280 296 4.2E-9 T 29-03-2018 SMALA_RS31550 3dbd992f1faffedce26556821ddde365 469 PRINTS PR00145 Argininosuccinate lyase family signature 104 126 4.2E-9 T 29-03-2018 SMALA_RS31550 3dbd992f1faffedce26556821ddde365 469 PRINTS PR00145 Argininosuccinate lyase family signature 145 165 4.2E-9 T 29-03-2018 SMALA_RS31550 3dbd992f1faffedce26556821ddde365 469 PRINTS PR00145 Argininosuccinate lyase family signature 235 259 4.2E-9 T 29-03-2018 SMALA_RS09535 f50572679e96808aa5b82fe039216fcb 510 ProSitePatterns PS00069 Glucose-6-phosphate dehydrogenase active site. 201 207 - T 29-03-2018 IPR019796 Glucose-6-phosphate dehydrogenase, active site GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 SMALA_RS09535 f50572679e96808aa5b82fe039216fcb 510 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 26 509 2.4E-201 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 SMALA_RS09535 f50572679e96808aa5b82fe039216fcb 510 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 24 509 88.353 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 SMALA_RS09535 f50572679e96808aa5b82fe039216fcb 510 PIRSF PIRSF000110 5 510 7.0E-182 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 SMALA_RS09535 f50572679e96808aa5b82fe039216fcb 510 SUPERFAMILY SSF51735 13 214 1.87E-61 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS09535 f50572679e96808aa5b82fe039216fcb 510 Gene3D G3DSA:3.40.50.720 22 212 7.1E-68 T 29-03-2018 SMALA_RS09535 f50572679e96808aa5b82fe039216fcb 510 SUPERFAMILY SSF55347 201 508 5.89E-115 T 29-03-2018 SMALA_RS09535 f50572679e96808aa5b82fe039216fcb 510 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 243 260 1.2E-47 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 SMALA_RS09535 f50572679e96808aa5b82fe039216fcb 510 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 350 376 1.2E-47 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 SMALA_RS09535 f50572679e96808aa5b82fe039216fcb 510 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 261 277 1.2E-47 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 SMALA_RS09535 f50572679e96808aa5b82fe039216fcb 510 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 191 219 1.2E-47 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 SMALA_RS09535 f50572679e96808aa5b82fe039216fcb 510 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 167 180 1.2E-47 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 SMALA_RS09535 f50572679e96808aa5b82fe039216fcb 510 Gene3D G3DSA:3.30.360.10 213 510 2.9E-128 T 29-03-2018 SMALA_RS09535 f50572679e96808aa5b82fe039216fcb 510 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 213 508 1.3E-116 T 29-03-2018 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 SMALA_RS09535 f50572679e96808aa5b82fe039216fcb 510 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 28 211 2.3E-61 T 29-03-2018 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 SMALA_RS02705 a5245b9f24796ef03999e38a0e8ef6e2 452 SUPERFAMILY SSF103473 181 426 2.49E-22 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS02705 a5245b9f24796ef03999e38a0e8ef6e2 452 Gene3D G3DSA:1.20.1250.20 239 433 6.5E-17 T 29-03-2018 SMALA_RS02705 a5245b9f24796ef03999e38a0e8ef6e2 452 SUPERFAMILY SSF103473 10 152 1.31E-10 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS02705 a5245b9f24796ef03999e38a0e8ef6e2 452 Pfam PF07690 Major Facilitator Superfamily 46 332 1.7E-12 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS02705 a5245b9f24796ef03999e38a0e8ef6e2 452 Gene3D G3DSA:1.20.1250.20 25 238 7.1E-11 T 29-03-2018 SMALA_RS25070 ec271277e123f46b82e4fb7da1940790 180 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 55 3.8E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS25070 ec271277e123f46b82e4fb7da1940790 180 Gene3D G3DSA:1.10.260.40 36 63 1.7E-11 T 29-03-2018 SMALA_RS25070 ec271277e123f46b82e4fb7da1940790 180 SUPERFAMILY SSF46689 1 68 1.3E-10 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS25070 ec271277e123f46b82e4fb7da1940790 180 Gene3D G3DSA:1.10.10.60 1 35 1.1E-8 T 29-03-2018 SMALA_RS25070 ec271277e123f46b82e4fb7da1940790 180 Gene3D G3DSA:1.10.357.10 64 180 2.8E-9 T 29-03-2018 SMALA_RS08450 be6a402a8b24dc05d0bfa81725c802c0 416 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 41 290 3.0E-28 T 29-03-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 SMALA_RS08450 be6a402a8b24dc05d0bfa81725c802c0 416 Gene3D G3DSA:2.40.37.10 281 416 6.1E-33 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 SMALA_RS08450 be6a402a8b24dc05d0bfa81725c802c0 416 Gene3D G3DSA:3.20.20.10 39 280 1.2E-55 T 29-03-2018 IPR029066 PLP-binding barrel SMALA_RS08450 be6a402a8b24dc05d0bfa81725c802c0 416 SUPERFAMILY SSF51419 37 294 3.79E-54 T 29-03-2018 IPR029066 PLP-binding barrel SMALA_RS08450 be6a402a8b24dc05d0bfa81725c802c0 416 SUPERFAMILY SSF50621 258 413 3.98E-34 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 SMALA_RS08450 be6a402a8b24dc05d0bfa81725c802c0 416 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 80 92 4.1E-9 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMALA_RS08450 be6a402a8b24dc05d0bfa81725c802c0 416 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 60 78 4.1E-9 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMALA_RS08450 be6a402a8b24dc05d0bfa81725c802c0 416 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 281 300 4.1E-9 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMALA_RS08450 be6a402a8b24dc05d0bfa81725c802c0 416 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 198 211 4.1E-9 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMALA_RS08450 be6a402a8b24dc05d0bfa81725c802c0 416 PRINTS PR01182 Ornithine decarboxylase signature 379 392 4.3E-6 T 29-03-2018 IPR002433 Ornithine decarboxylase GO:0006596 SMALA_RS08450 be6a402a8b24dc05d0bfa81725c802c0 416 PRINTS PR01182 Ornithine decarboxylase signature 101 125 4.3E-6 T 29-03-2018 IPR002433 Ornithine decarboxylase GO:0006596 SMALA_RS08450 be6a402a8b24dc05d0bfa81725c802c0 416 PRINTS PR01182 Ornithine decarboxylase signature 58 85 4.3E-6 T 29-03-2018 IPR002433 Ornithine decarboxylase GO:0006596 SMALA_RS08450 be6a402a8b24dc05d0bfa81725c802c0 416 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 236 250 - T 29-03-2018 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site SMALA_RS08450 be6a402a8b24dc05d0bfa81725c802c0 416 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 34 392 1.7E-15 T 29-03-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 SMALA_RS10695 a7691be62a93f4b5d5bf3ef325346626 302 Gene3D G3DSA:3.40.50.720 4 301 3.2E-33 T 29-03-2018 SMALA_RS10695 a7691be62a93f4b5d5bf3ef325346626 302 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 126 1.3E-12 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 SMALA_RS10695 a7691be62a93f4b5d5bf3ef325346626 302 SUPERFAMILY SSF51735 4 292 9.53E-41 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS10695 a7691be62a93f4b5d5bf3ef325346626 302 TIGRFAM TIGR01777 yfcH: TIGR01777 family protein 6 294 1.7E-99 T 29-03-2018 IPR010099 Epimerase family protein SDR39U1 SMALA_RS10695 a7691be62a93f4b5d5bf3ef325346626 302 Pfam PF08338 Domain of unknown function (DUF1731) 251 296 2.6E-17 T 29-03-2018 IPR013549 Domain of unknown function DUF1731 SMALA_RS13430 af511b8c9dd221f30314bc3a73efc86d 442 Gene3D G3DSA:3.40.190.10 31 205 4.0E-39 T 29-03-2018 SMALA_RS13430 af511b8c9dd221f30314bc3a73efc86d 442 Pfam PF01547 Bacterial extracellular solute-binding protein 49 350 5.5E-35 T 29-03-2018 IPR006059 Solute-binding family 1 GO:0006810 SMALA_RS13430 af511b8c9dd221f30314bc3a73efc86d 442 Gene3D G3DSA:3.40.190.10 263 393 1.1E-12 T 29-03-2018 SMALA_RS13430 af511b8c9dd221f30314bc3a73efc86d 442 SUPERFAMILY SSF53850 20 436 6.52E-63 T 29-03-2018 SMALA_RS21805 ad5f48df43e8da4331286403bb2934e6 268 Pfam PF08281 Sigma-70, region 4 208 259 9.2E-14 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS21805 ad5f48df43e8da4331286403bb2934e6 268 SUPERFAMILY SSF88946 87 195 7.65E-27 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS21805 ad5f48df43e8da4331286403bb2934e6 268 Gene3D G3DSA:1.10.1740.10 86 180 1.3E-24 T 29-03-2018 SMALA_RS21805 ad5f48df43e8da4331286403bb2934e6 268 TIGRFAM TIGR02952 Sig70_famx2: RNA polymerase sigma-70 factor, TIGR02952 family 94 263 6.5E-78 T 29-03-2018 IPR014298 RNA polymerase sigma-X type SMALA_RS21805 ad5f48df43e8da4331286403bb2934e6 268 Pfam PF04542 Sigma-70 region 2 109 176 1.4E-17 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS21805 ad5f48df43e8da4331286403bb2934e6 268 SUPERFAMILY SSF88659 193 263 1.78E-13 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS21805 ad5f48df43e8da4331286403bb2934e6 268 Gene3D G3DSA:1.10.10.10 181 266 1.8E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS21805 ad5f48df43e8da4331286403bb2934e6 268 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 104 261 1.3E-29 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS36245 1e9f1f571c7aa6dc3620da6eef3cc168 1504 Pfam PF00689 Cation transporting ATPase, C-terminus 1316 1468 2.6E-17 T 29-03-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 SMALA_RS36245 1e9f1f571c7aa6dc3620da6eef3cc168 1504 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 951 957 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 SMALA_RS36245 1e9f1f571c7aa6dc3620da6eef3cc168 1504 Pfam PF00702 haloacid dehalogenase-like hydrolase 946 1245 4.2E-25 T 29-03-2018 SMALA_RS36245 1e9f1f571c7aa6dc3620da6eef3cc168 1504 Pfam PF00122 E1-E2 ATPase 744 928 3.5E-43 T 29-03-2018 SMALA_RS36245 1e9f1f571c7aa6dc3620da6eef3cc168 1504 Gene3D G3DSA:2.70.150.10 630 853 5.8E-33 T 29-03-2018 SMALA_RS36245 1e9f1f571c7aa6dc3620da6eef3cc168 1504 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 714 968 5.8E-31 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMALA_RS36245 1e9f1f571c7aa6dc3620da6eef3cc168 1504 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 1203 1314 2.0E-26 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMALA_RS36245 1e9f1f571c7aa6dc3620da6eef3cc168 1504 Gene3D G3DSA:1.20.1110.10 1152 1473 3.9E-57 T 29-03-2018 SMALA_RS36245 1e9f1f571c7aa6dc3620da6eef3cc168 1504 SUPERFAMILY SSF81660 998 1134 3.71E-18 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 SMALA_RS36245 1e9f1f571c7aa6dc3620da6eef3cc168 1504 Gene3D G3DSA:3.30.70.100 65 131 9.7E-6 T 29-03-2018 SMALA_RS36245 1e9f1f571c7aa6dc3620da6eef3cc168 1504 Gene3D G3DSA:3.40.1110.10 913 1137 2.2E-33 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 SMALA_RS36245 1e9f1f571c7aa6dc3620da6eef3cc168 1504 SUPERFAMILY SSF56784 947 967 1.6E-46 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS36245 1e9f1f571c7aa6dc3620da6eef3cc168 1504 SUPERFAMILY SSF56784 1087 1336 1.6E-46 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS36245 1e9f1f571c7aa6dc3620da6eef3cc168 1504 SUPERFAMILY SSF81653 744 846 3.14E-26 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 SMALA_RS36245 1e9f1f571c7aa6dc3620da6eef3cc168 1504 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 1152 1162 2.2E-30 T 29-03-2018 SMALA_RS36245 1e9f1f571c7aa6dc3620da6eef3cc168 1504 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 1231 1250 2.2E-30 T 29-03-2018 SMALA_RS36245 1e9f1f571c7aa6dc3620da6eef3cc168 1504 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 1130 1141 2.2E-30 T 29-03-2018 SMALA_RS36245 1e9f1f571c7aa6dc3620da6eef3cc168 1504 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 1255 1267 2.2E-30 T 29-03-2018 SMALA_RS36245 1e9f1f571c7aa6dc3620da6eef3cc168 1504 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 949 963 2.2E-30 T 29-03-2018 SMALA_RS36245 1e9f1f571c7aa6dc3620da6eef3cc168 1504 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 789 803 2.2E-30 T 29-03-2018 SMALA_RS36245 1e9f1f571c7aa6dc3620da6eef3cc168 1504 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 1263 1288 1.3E-15 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMALA_RS36245 1e9f1f571c7aa6dc3620da6eef3cc168 1504 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 1090 1108 1.3E-15 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMALA_RS36245 1e9f1f571c7aa6dc3620da6eef3cc168 1504 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 1203 1219 1.3E-15 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMALA_RS36245 1e9f1f571c7aa6dc3620da6eef3cc168 1504 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 1231 1247 1.3E-15 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMALA_RS36245 1e9f1f571c7aa6dc3620da6eef3cc168 1504 Gene3D G3DSA:3.40.50.1000 328 570 0.026 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS36245 1e9f1f571c7aa6dc3620da6eef3cc168 1504 SMART SM00831 633 704 8.9E-5 T 29-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 SMALA_RS36245 1e9f1f571c7aa6dc3620da6eef3cc168 1504 SUPERFAMILY SSF55008 66 128 1.66E-5 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 SMALA_RS36245 1e9f1f571c7aa6dc3620da6eef3cc168 1504 SUPERFAMILY SSF81665 850 943 5.36E-57 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SMALA_RS36245 1e9f1f571c7aa6dc3620da6eef3cc168 1504 SUPERFAMILY SSF81665 1281 1468 5.36E-57 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SMALA_RS36245 1e9f1f571c7aa6dc3620da6eef3cc168 1504 SUPERFAMILY SSF81665 633 742 5.36E-57 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SMALA_RS23130 ac00b2628751587312d489ccc341e6ea 885 Gene3D G3DSA:3.30.200.20 3 113 1.8E-11 T 29-03-2018 SMALA_RS23130 ac00b2628751587312d489ccc341e6ea 885 SMART SM00564 850 881 4.5 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMALA_RS23130 ac00b2628751587312d489ccc341e6ea 885 SMART SM00564 523 552 25.0 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMALA_RS23130 ac00b2628751587312d489ccc341e6ea 885 SMART SM00564 557 588 21.0 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMALA_RS23130 ac00b2628751587312d489ccc341e6ea 885 SMART SM00564 809 841 0.86 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMALA_RS23130 ac00b2628751587312d489ccc341e6ea 885 SMART SM00564 639 670 6.0E-4 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMALA_RS23130 ac00b2628751587312d489ccc341e6ea 885 SMART SM00564 730 761 1.3E-5 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMALA_RS23130 ac00b2628751587312d489ccc341e6ea 885 SMART SM00564 684 715 1.4 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMALA_RS23130 ac00b2628751587312d489ccc341e6ea 885 SMART SM00564 595 627 2.2 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMALA_RS23130 ac00b2628751587312d489ccc341e6ea 885 SMART SM00564 770 801 15.0 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMALA_RS23130 ac00b2628751587312d489ccc341e6ea 885 Pfam PF13570 PQQ-like domain 511 544 0.0014 T 29-03-2018 IPR025666 Pyrrolo-quinoline quinone-like domain SMALA_RS23130 ac00b2628751587312d489ccc341e6ea 885 Pfam PF13360 PQQ-like domain 729 875 4.9E-20 T 29-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat SMALA_RS23130 ac00b2628751587312d489ccc341e6ea 885 Pfam PF13360 PQQ-like domain 559 715 1.0E-20 T 29-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat SMALA_RS23130 ac00b2628751587312d489ccc341e6ea 885 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 22 44 - T 29-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 SMALA_RS23130 ac00b2628751587312d489ccc341e6ea 885 SMART SM00220 16 271 9.7E-40 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMALA_RS23130 ac00b2628751587312d489ccc341e6ea 885 SUPERFAMILY SSF50998 729 875 3.14E-27 T 29-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily SMALA_RS23130 ac00b2628751587312d489ccc341e6ea 885 Gene3D G3DSA:1.10.510.10 114 296 4.4E-41 T 29-03-2018 SMALA_RS23130 ac00b2628751587312d489ccc341e6ea 885 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 134 146 - T 29-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMALA_RS23130 ac00b2628751587312d489ccc341e6ea 885 Gene3D G3DSA:2.140.10.10 322 632 1.1E-21 T 29-03-2018 SMALA_RS23130 ac00b2628751587312d489ccc341e6ea 885 SUPERFAMILY SSF56112 12 294 2.83E-61 T 29-03-2018 IPR011009 Protein kinase-like domain SMALA_RS23130 ac00b2628751587312d489ccc341e6ea 885 SUPERFAMILY SSF50998 555 762 3.92E-34 T 29-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily SMALA_RS23130 ac00b2628751587312d489ccc341e6ea 885 Gene3D G3DSA:2.140.10.10 768 879 4.7E-20 T 29-03-2018 SMALA_RS23130 ac00b2628751587312d489ccc341e6ea 885 Pfam PF00069 Protein kinase domain 16 262 4.1E-37 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMALA_RS23130 ac00b2628751587312d489ccc341e6ea 885 Gene3D G3DSA:2.140.10.10 633 767 3.5E-24 T 29-03-2018 SMALA_RS14120 016e549249634ce527b867686c3c38a4 225 ProSitePatterns PS00622 LuxR-type HTH domain signature. 174 201 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS14120 016e549249634ce527b867686c3c38a4 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 190 202 1.3E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS14120 016e549249634ce527b867686c3c38a4 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 160 174 1.3E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS14120 016e549249634ce527b867686c3c38a4 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 174 190 1.3E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS14120 016e549249634ce527b867686c3c38a4 225 Pfam PF00196 Bacterial regulatory proteins, luxR family 160 214 3.2E-19 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS14120 016e549249634ce527b867686c3c38a4 225 SUPERFAMILY SSF52172 4 136 1.21E-33 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS14120 016e549249634ce527b867686c3c38a4 225 SMART SM00421 157 214 3.8E-26 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS14120 016e549249634ce527b867686c3c38a4 225 SMART SM00448 5 119 5.0E-32 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS14120 016e549249634ce527b867686c3c38a4 225 SUPERFAMILY SSF46894 148 220 3.74E-23 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS14120 016e549249634ce527b867686c3c38a4 225 Pfam PF00072 Response regulator receiver domain 7 119 1.2E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS14120 016e549249634ce527b867686c3c38a4 225 Gene3D G3DSA:1.10.10.10 138 219 6.4E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS14120 016e549249634ce527b867686c3c38a4 225 Gene3D G3DSA:3.40.50.2300 4 137 6.7E-37 T 29-03-2018 SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 SMART SM00826 1976 2141 1.3E-44 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 SMART SM00826 3677 3830 1.1E-25 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 Gene3D G3DSA:1.10.1200.10 2638 2753 8.8E-17 T 29-03-2018 SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 3306 3609 8.9E-112 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1610 1909 8.8E-106 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 4616 4918 8.1E-110 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 SUPERFAMILY SSF47336 5533 5617 1.44E-17 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2699 2714 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 SUPERFAMILY SSF52151 1800 1898 4.97E-61 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 SUPERFAMILY SSF52151 1606 1735 4.97E-61 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 Gene3D G3DSA:3.40.366.10 1603 1748 1.6E-38 T 29-03-2018 SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 SUPERFAMILY SSF55048 1734 1798 1.44E-12 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 Gene3D G3DSA:3.40.50.980 224 374 1.4E-38 T 29-03-2018 SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 Gene3D G3DSA:3.30.300.30 458 566 2.5E-23 T 29-03-2018 SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 Gene3D G3DSA:2.30.38.10 375 457 5.3E-30 T 29-03-2018 SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 Gene3D G3DSA:3.40.47.10 1069 1338 1.4E-81 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 Gene3D G3DSA:3.40.47.10 4085 4345 9.0E-87 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 Gene3D G3DSA:3.40.47.10 2761 3029 1.4E-85 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5253 5435 1.2E-23 T 29-03-2018 SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2383 2563 2.0E-56 T 29-03-2018 SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1239 1255 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 ProSitePatterns PS00012 Phosphopantetheine attachment site. 5568 5583 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 Pfam PF13193 AMP-binding enzyme C-terminal domain 473 547 6.2E-15 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 SMART SM00825 Beta-ketoacyl synthase 2770 3195 7.4E-212 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 SMART SM00825 Beta-ketoacyl synthase 1079 1504 2.2E-214 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 SMART SM00825 Beta-ketoacyl synthase 4086 4512 5.8E-213 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 Gene3D G3DSA:3.40.47.10 1341 1502 3.5E-59 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 Gene3D G3DSA:3.40.47.10 4349 4510 3.4E-62 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 Gene3D G3DSA:3.40.47.10 3032 3193 3.8E-60 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 Gene3D G3DSA:3.40.366.10 1792 1915 7.2E-23 T 29-03-2018 SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 Gene3D G3DSA:3.40.366.10 4800 4915 7.8E-25 T 29-03-2018 SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 Gene3D G3DSA:3.40.366.10 3493 3618 1.7E-29 T 29-03-2018 SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 SMART SM00823 Phosphopantetheine attachment site 987 1059 1.4E-22 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 SMART SM00823 Phosphopantetheine attachment site 2672 2744 2.5E-24 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 SMART SM00823 Phosphopantetheine attachment site 3987 4059 5.4E-27 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 SMART SM00823 Phosphopantetheine attachment site 5541 5613 3.4E-25 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 SUPERFAMILY SSF55048 3437 3500 1.83E-11 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 Gene3D G3DSA:1.10.1200.10 963 1061 1.2E-14 T 29-03-2018 SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 3025 3142 5.0E-43 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1334 1451 9.2E-42 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 4342 4459 1.4E-42 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 Gene3D G3DSA:3.30.70.250 3451 3492 1.0E-18 T 29-03-2018 SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 Gene3D G3DSA:3.30.70.250 1749 1791 5.7E-17 T 29-03-2018 SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 Gene3D G3DSA:3.30.70.250 4749 4799 2.1E-12 T 29-03-2018 SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 Gene3D G3DSA:1.10.1200.10 5535 5688 1.4E-17 T 29-03-2018 SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 Gene3D G3DSA:1.10.1200.10 3979 4084 3.9E-19 T 29-03-2018 SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 Pfam PF00501 AMP-binding enzyme 55 464 2.9E-110 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 SUPERFAMILY SSF52151 3502 3594 4.97E-71 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 SUPERFAMILY SSF52151 3302 3438 4.97E-71 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 Gene3D G3DSA:3.40.50.720 753 962 1.8E-5 T 29-03-2018 SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 Pfam PF00550 Phosphopantetheine attachment site 2675 2740 7.1E-8 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 Pfam PF00550 Phosphopantetheine attachment site 5544 5609 4.8E-8 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 Pfam PF00550 Phosphopantetheine attachment site 3990 4055 1.6E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 Pfam PF00550 Phosphopantetheine attachment site 1008 1055 1.3E-8 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 SUPERFAMILY SSF47336 3981 4099 5.37E-20 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 SMART SM01294 3988 4055 6.3E-4 T 29-03-2018 SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 SUPERFAMILY SSF55048 4740 4802 1.83E-9 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 SUPERFAMILY SSF53901 4080 4458 2.56E-101 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 SUPERFAMILY SSF51735 2381 2610 6.33E-45 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 Pfam PF14765 Polyketide synthase dehydratase 3713 3869 1.2E-10 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 Pfam PF14765 Polyketide synthase dehydratase 1976 2112 4.2E-18 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 Gene3D G3DSA:3.40.50.720 5246 5508 1.8E-34 T 29-03-2018 SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 Gene3D G3DSA:3.40.50.720 2375 2628 2.0E-45 T 29-03-2018 SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 Gene3D G3DSA:3.40.366.10 3302 3450 3.2E-41 T 29-03-2018 SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 Gene3D G3DSA:3.40.366.10 4612 4748 4.3E-42 T 29-03-2018 SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 SUPERFAMILY SSF51735 5033 5239 6.69E-38 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 SUPERFAMILY SSF51735 574 746 1.69E-13 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 SUPERFAMILY SSF51735 5249 5509 4.56E-27 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 ProSitePatterns PS00455 Putative AMP-binding domain signature. 217 228 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 2930 2946 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 SUPERFAMILY SSF53901 1075 1448 2.12E-101 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 Pfam PF08659 KR domain 5253 5433 1.5E-38 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 Pfam PF08659 KR domain 2383 2561 1.4E-56 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 4247 4263 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 SUPERFAMILY SSF51735 2213 2371 4.72E-18 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1014 1029 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 SUPERFAMILY SSF52151 4612 4742 3.66E-67 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 SUPERFAMILY SSF52151 4806 4899 3.66E-67 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4014 4029 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 SUPERFAMILY SSF56801 53 558 1.31E-152 T 29-03-2018 SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 SUPERFAMILY SSF47336 987 1092 2.36E-19 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 Pfam PF00698 Acyl transferase domain 3305 3587 3.6E-55 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 Pfam PF00698 Acyl transferase domain 4615 4936 4.8E-79 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 Pfam PF00698 Acyl transferase domain 1609 1927 7.5E-73 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1454 1544 2.3E-11 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 3145 3268 2.0E-17 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 4462 4565 3.9E-13 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 Gene3D G3DSA:3.40.50.980 48 223 7.3E-40 T 29-03-2018 SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4084 4334 8.6E-89 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2768 3017 1.2E-87 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1077 1326 1.0E-89 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 SUPERFAMILY SSF51735 761 947 6.16E-7 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 SUPERFAMILY SSF53901 2765 3139 2.16E-102 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS06890 69c224eeedab1e7ddd46b6a48e47b63b 5699 SUPERFAMILY SSF47336 2666 2748 3.01E-17 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS30860 e98bac969b30639dc4237c23e74931c2 288 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 95 116 - T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 SMALA_RS30860 e98bac969b30639dc4237c23e74931c2 288 Pfam PF01066 CDP-alcohol phosphatidyltransferase 37 116 2.1E-10 T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 SMALA_RS30860 e98bac969b30639dc4237c23e74931c2 288 TIGRFAM TIGR00473 pssA: CDP-diacylglycerol-serine O-phosphatidyltransferase 42 214 1.9E-32 T 29-03-2018 IPR004533 CDP-diacylglycerol--serine O-phosphatidyltransferase KEGG: 00260+2.7.8.8|KEGG: 00564+2.7.8.8|MetaCyc: PWY-5669 SMALA_RS01225 fa3866ec1c9618b6c71bca10502c291c 293 SMART SM00347 146 248 1.3E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS01225 fa3866ec1c9618b6c71bca10502c291c 293 PRINTS PR00598 Bacterial regulatory protein MarR family signature 208 224 2.6E-5 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS01225 fa3866ec1c9618b6c71bca10502c291c 293 PRINTS PR00598 Bacterial regulatory protein MarR family signature 238 258 2.6E-5 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS01225 fa3866ec1c9618b6c71bca10502c291c 293 PRINTS PR00598 Bacterial regulatory protein MarR family signature 189 204 2.6E-5 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS01225 fa3866ec1c9618b6c71bca10502c291c 293 Pfam PF12802 MarR family 153 211 3.5E-12 T 29-03-2018 SMALA_RS01225 fa3866ec1c9618b6c71bca10502c291c 293 SUPERFAMILY SSF46785 150 263 2.4E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS01225 fa3866ec1c9618b6c71bca10502c291c 293 Gene3D G3DSA:1.10.10.10 57 266 1.9E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS01310 45731c9f4d0ebf0c2e3236667b99e8f6 292 Gene3D G3DSA:1.10.260.40 1 101 1.7E-14 T 29-03-2018 SMALA_RS01310 45731c9f4d0ebf0c2e3236667b99e8f6 292 SUPERFAMILY SSF47413 30 77 1.78E-7 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS01310 45731c9f4d0ebf0c2e3236667b99e8f6 292 SMART SM00530 10 82 3.3E-5 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS01310 45731c9f4d0ebf0c2e3236667b99e8f6 292 Pfam PF13560 Helix-turn-helix domain 7 85 3.7E-15 T 29-03-2018 SMALA_RS08140 8cd7ebf82621874a81511bd95d8a10dd 272 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 131 159 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMALA_RS08140 8cd7ebf82621874a81511bd95d8a10dd 272 Pfam PF00106 short chain dehydrogenase 9 185 9.4E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS08140 8cd7ebf82621874a81511bd95d8a10dd 272 Gene3D G3DSA:3.40.50.720 2 252 2.4E-47 T 29-03-2018 SMALA_RS08140 8cd7ebf82621874a81511bd95d8a10dd 272 SUPERFAMILY SSF51735 5 229 7.65E-52 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS08140 8cd7ebf82621874a81511bd95d8a10dd 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 7.6E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS08140 8cd7ebf82621874a81511bd95d8a10dd 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 163 7.6E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS08140 8cd7ebf82621874a81511bd95d8a10dd 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 118 134 7.6E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS08140 8cd7ebf82621874a81511bd95d8a10dd 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 7.6E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS08140 8cd7ebf82621874a81511bd95d8a10dd 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 182 7.6E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS04795 386059f5ca43b6c3b6c428c0b3c34364 157 PRINTS PR00598 Bacterial regulatory protein MarR family signature 61 77 1.4E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS04795 386059f5ca43b6c3b6c428c0b3c34364 157 PRINTS PR00598 Bacterial regulatory protein MarR family signature 78 93 1.4E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS04795 386059f5ca43b6c3b6c428c0b3c34364 157 PRINTS PR00598 Bacterial regulatory protein MarR family signature 97 113 1.4E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS04795 386059f5ca43b6c3b6c428c0b3c34364 157 PRINTS PR00598 Bacterial regulatory protein MarR family signature 127 147 1.4E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS04795 386059f5ca43b6c3b6c428c0b3c34364 157 SUPERFAMILY SSF46785 22 151 4.42E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS04795 386059f5ca43b6c3b6c428c0b3c34364 157 SMART SM00347 37 137 1.1E-20 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS04795 386059f5ca43b6c3b6c428c0b3c34364 157 Pfam PF01047 MarR family 50 101 7.3E-16 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS04795 386059f5ca43b6c3b6c428c0b3c34364 157 Gene3D G3DSA:1.10.10.10 2 155 4.6E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1208 1224 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2441 2456 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 Gene3D G3DSA:3.40.366.10 742 867 7.5E-29 T 29-03-2018 SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 SUPERFAMILY SSF52151 3028 3152 7.06E-66 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 SUPERFAMILY SSF52151 3207 3303 7.06E-66 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 SUPERFAMILY SSF51735 1919 2127 1.38E-40 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 Gene3D G3DSA:1.10.1200.10 949 1045 2.3E-18 T 29-03-2018 SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 Gene3D G3DSA:1.10.1200.10 2407 2511 1.1E-19 T 29-03-2018 SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 SUPERFAMILY SSF52151 4889 4977 2.04E-69 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 SUPERFAMILY SSF52151 4703 4828 2.04E-69 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 SMART SM01294 957 1024 4.0E-4 T 29-03-2018 SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 SMART SM01294 2415 2482 1.0E-5 T 29-03-2018 SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 SMART SM01294 4090 4157 2.5E-5 T 29-03-2018 SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 SMART SM01294 5552 5619 9.1E-6 T 29-03-2018 SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 SMART SM00823 Phosphopantetheine attachment site 4089 4161 4.9E-31 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 SMART SM00823 Phosphopantetheine attachment site 2414 2486 7.1E-31 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 SMART SM00823 Phosphopantetheine attachment site 5551 5623 4.0E-32 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 SMART SM00823 Phosphopantetheine attachment site 956 1028 1.5E-27 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 SUPERFAMILY SSF51735 5282 5541 2.66E-44 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 SUPERFAMILY SSF53901 3 393 5.26E-90 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 Pfam PF08659 KR domain 3808 3984 5.9E-52 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 Pfam PF08659 KR domain 2139 2313 3.5E-54 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 Pfam PF08659 KR domain 5286 5461 5.2E-50 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 SUPERFAMILY SSF55048 3150 3202 1.23E-6 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 SUPERFAMILY SSF53901 2509 2879 9.41E-101 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 ProSitePatterns PS00012 Phosphopantetheine attachment site. 983 998 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3808 3985 7.3E-45 T 29-03-2018 SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5286 5462 7.4E-44 T 29-03-2018 SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2139 2315 1.6E-48 T 29-03-2018 SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 SUPERFAMILY SSF47336 2412 2527 1.31E-23 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 Gene3D G3DSA:1.10.1200.10 5535 5624 8.1E-21 T 29-03-2018 SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 559 858 1.3E-118 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 4704 4988 7.6E-117 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 3030 3315 1.7E-110 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1577 1865 5.5E-113 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 Gene3D G3DSA:3.40.366.10 4879 4978 7.4E-28 T 29-03-2018 SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 Gene3D G3DSA:3.40.366.10 3016 3312 8.4E-75 T 29-03-2018 SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 Gene3D G3DSA:3.40.366.10 1563 1864 2.1E-76 T 29-03-2018 SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 Gene3D G3DSA:3.40.47.10 4444 4605 1.3E-63 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 Gene3D G3DSA:3.40.47.10 1310 1469 9.2E-64 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 Gene3D G3DSA:3.40.47.10 2771 2932 4.2E-63 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 Pfam PF14765 Polyketide synthase dehydratase 3377 3647 1.1E-52 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 Gene3D G3DSA:3.40.47.10 2512 2768 5.7E-80 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 Gene3D G3DSA:3.40.47.10 4172 4441 3.0E-82 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 Gene3D G3DSA:3.40.47.10 1 282 1.3E-81 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 Gene3D G3DSA:3.40.47.10 1046 1307 6.2E-85 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 SUPERFAMILY SSF52151 1574 1699 4.71E-67 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 SUPERFAMILY SSF52151 1754 1855 4.71E-67 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 Gene3D G3DSA:3.30.70.250 694 741 3.5E-18 T 29-03-2018 SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 Gene3D G3DSA:3.30.70.250 4838 4878 1.9E-17 T 29-03-2018 SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4180 4429 2.3E-85 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 5 270 1.3E-75 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1048 1295 1.7E-90 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2512 2756 1.0E-85 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 SMART SM00825 Beta-ketoacyl synthase 4182 4607 1.7E-223 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 SMART SM00825 Beta-ketoacyl synthase 7 446 1.9E-190 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 SMART SM00825 Beta-ketoacyl synthase 2514 2934 2.1E-219 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 SMART SM00825 Beta-ketoacyl synthase 1050 1471 2.9E-223 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 Gene3D G3DSA:3.40.366.10 552 693 2.8E-43 T 29-03-2018 SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 Gene3D G3DSA:3.40.366.10 4697 4837 6.1E-45 T 29-03-2018 SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 SUPERFAMILY SSF52151 752 850 1.41E-71 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 SUPERFAMILY SSF52151 555 683 1.41E-71 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 SUPERFAMILY SSF51735 3655 3796 5.51E-23 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 SUPERFAMILY SSF47336 5544 5626 1.44E-21 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 SUPERFAMILY SSF47336 953 1061 5.23E-21 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1303 1420 5.9E-45 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 4437 4554 9.1E-46 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 278 393 1.8E-38 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2764 2881 4.6E-45 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 Gene3D G3DSA:1.10.1200.10 4071 4164 1.6E-20 T 29-03-2018 SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 Pfam PF00698 Acyl transferase domain 3029 3334 4.6E-80 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 Pfam PF00698 Acyl transferase domain 1575 1884 4.6E-83 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 Pfam PF00698 Acyl transferase domain 4704 4973 3.3E-49 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 Pfam PF00698 Acyl transferase domain 558 877 2.0E-54 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 SUPERFAMILY SSF51735 2135 2366 7.17E-45 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 4342 4358 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 Pfam PF00550 Phosphopantetheine attachment site 959 1024 7.4E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 Pfam PF00550 Phosphopantetheine attachment site 5553 5619 1.5E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 Pfam PF00550 Phosphopantetheine attachment site 2416 2482 5.8E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 Pfam PF00550 Phosphopantetheine attachment site 4091 4157 8.3E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 2669 2685 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 SMART SM00826 3377 3535 2.5E-67 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4116 4131 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 SUPERFAMILY SSF47336 4083 4195 1.96E-24 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 Gene3D G3DSA:3.40.50.720 2131 2385 4.2E-52 T 29-03-2018 SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 Gene3D G3DSA:3.40.50.720 3801 4058 2.8E-41 T 29-03-2018 SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 Gene3D G3DSA:3.40.50.720 5280 5526 4.7E-47 T 29-03-2018 SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 Gene3D G3DSA:3.40.47.10 286 448 8.5E-55 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 SUPERFAMILY SSF55048 1697 1749 7.72E-7 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 SUPERFAMILY SSF55048 4827 4888 7.06E-11 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 SUPERFAMILY SSF53901 4176 4552 2.07E-99 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 SUPERFAMILY SSF53901 1046 1417 5.62E-104 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 SUPERFAMILY SSF55048 682 751 7.85E-9 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 ProSitePatterns PS00012 Phosphopantetheine attachment site. 5578 5593 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 SUPERFAMILY SSF51735 3805 4036 3.43E-41 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 SUPERFAMILY SSF51735 5089 5271 7.48E-40 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2884 3001 5.6E-16 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1423 1541 2.5E-15 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 396 522 1.8E-13 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS02625 6d3cc8c7f728c418dad93c18cb559a37 5703 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 4557 4676 5.7E-14 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS33065 d0c56e3b3dd681eedf30e6453a1eb61b 188 Gene3D G3DSA:2.40.50.140 66 127 5.9E-23 T 29-03-2018 SMALA_RS33065 d0c56e3b3dd681eedf30e6453a1eb61b 188 TIGRFAM TIGR00038 efp: translation elongation factor P 3 186 2.3E-74 T 29-03-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 SMALA_RS33065 d0c56e3b3dd681eedf30e6453a1eb61b 188 SMART SM01185 68 122 1.6E-25 T 29-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 SMALA_RS33065 d0c56e3b3dd681eedf30e6453a1eb61b 188 Hamap MF_00141 Elongation factor P [efp]. 1 186 49.487 T 29-03-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 SMALA_RS33065 d0c56e3b3dd681eedf30e6453a1eb61b 188 ProSitePatterns PS01275 Elongation factor P signature. 151 170 - T 29-03-2018 IPR013852 Translation elongation factor P/YeiP, conserved site SMALA_RS33065 d0c56e3b3dd681eedf30e6453a1eb61b 188 Gene3D G3DSA:2.30.30.30 2 62 8.1E-26 T 29-03-2018 IPR014722 Ribosomal protein L2 domain 2 SMALA_RS33065 d0c56e3b3dd681eedf30e6453a1eb61b 188 SUPERFAMILY SSF50104 2 64 9.63E-19 T 29-03-2018 IPR008991 Translation protein SH3-like domain SMALA_RS33065 d0c56e3b3dd681eedf30e6453a1eb61b 188 Gene3D G3DSA:2.40.50.140 130 185 2.1E-26 T 29-03-2018 SMALA_RS33065 d0c56e3b3dd681eedf30e6453a1eb61b 188 Pfam PF09285 Elongation factor P, C-terminal 130 185 3.8E-25 T 29-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 SMALA_RS33065 d0c56e3b3dd681eedf30e6453a1eb61b 188 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 3 61 6.2E-26 T 29-03-2018 IPR013185 Translation elongation factor, KOW-like SMALA_RS33065 d0c56e3b3dd681eedf30e6453a1eb61b 188 SUPERFAMILY SSF50249 130 186 1.71E-17 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMALA_RS33065 d0c56e3b3dd681eedf30e6453a1eb61b 188 PIRSF PIRSF005901 1 187 4.1E-66 T 29-03-2018 IPR020599 Translation elongation factor P/YeiP SMALA_RS33065 d0c56e3b3dd681eedf30e6453a1eb61b 188 SMART SM00841 130 185 4.8E-31 T 29-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 SMALA_RS33065 d0c56e3b3dd681eedf30e6453a1eb61b 188 Pfam PF01132 Elongation factor P (EF-P) OB domain 69 122 5.6E-21 T 29-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 SMALA_RS33065 d0c56e3b3dd681eedf30e6453a1eb61b 188 SUPERFAMILY SSF50249 66 127 2.48E-18 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMALA_RS00515 07733b288d6b2e23e76ed8e162e17924 327 SUPERFAMILY SSF56176 1 219 1.91E-57 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SMALA_RS00515 07733b288d6b2e23e76ed8e162e17924 327 Gene3D G3DSA:3.30.390.50 222 327 2.3E-25 T 29-03-2018 SMALA_RS00515 07733b288d6b2e23e76ed8e162e17924 327 Gene3D G3DSA:3.30.43.10 1 50 1.1E-18 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 SMALA_RS00515 07733b288d6b2e23e76ed8e162e17924 327 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 226 322 1.2E-16 T 29-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal SMALA_RS00515 07733b288d6b2e23e76ed8e162e17924 327 Gene3D G3DSA:3.30.465.10 55 220 9.8E-31 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SMALA_RS00515 07733b288d6b2e23e76ed8e162e17924 327 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 3 219 1.0E-47 T 29-03-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 SMALA_RS00515 07733b288d6b2e23e76ed8e162e17924 327 SMART SM01092 225 323 8.2E-29 T 29-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal SMALA_RS00515 07733b288d6b2e23e76ed8e162e17924 327 SUPERFAMILY SSF55447 223 324 3.66E-27 T 29-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal SMALA_RS30130 ec711b87a8cbcf9f00ce1910eef18e73 416 SMART SM00530 19 75 2.7E-6 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS30130 ec711b87a8cbcf9f00ce1910eef18e73 416 Gene3D G3DSA:1.10.260.40 15 82 5.2E-13 T 29-03-2018 SMALA_RS30130 ec711b87a8cbcf9f00ce1910eef18e73 416 SUPERFAMILY SSF47413 11 71 5.07E-11 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS30130 ec711b87a8cbcf9f00ce1910eef18e73 416 Pfam PF13560 Helix-turn-helix domain 16 75 1.7E-11 T 29-03-2018 SMALA_RS35350 f6c1396002d611ed90634b3a51fce217 262 SMART SM00382 37 234 1.7E-21 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS35350 f6c1396002d611ed90634b3a51fce217 262 Pfam PF00005 ABC transporter 28 186 6.9E-35 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS35350 f6c1396002d611ed90634b3a51fce217 262 ProSitePatterns PS00211 ABC transporters family signature. 158 172 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS35350 f6c1396002d611ed90634b3a51fce217 262 Gene3D G3DSA:3.40.50.300 9 261 1.7E-78 T 29-03-2018 SMALA_RS35350 f6c1396002d611ed90634b3a51fce217 262 PIRSF PIRSF039085 9 262 5.8E-112 T 29-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 SMALA_RS35350 f6c1396002d611ed90634b3a51fce217 262 SUPERFAMILY SSF52540 13 256 3.39E-79 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS17705 dc4a3a8f2b6fda2a575bb82cc280799f 225 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 4 212 3.7E-56 T 29-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 SMALA_RS17705 dc4a3a8f2b6fda2a575bb82cc280799f 225 SUPERFAMILY SSF109755 2 218 2.62E-58 T 29-03-2018 SMALA_RS17705 dc4a3a8f2b6fda2a575bb82cc280799f 225 PIRSF PIRSF003107 1 217 1.5E-53 T 29-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 SMALA_RS17705 dc4a3a8f2b6fda2a575bb82cc280799f 225 Gene3D G3DSA:1.20.58.220 111 222 2.0E-18 T 29-03-2018 SMALA_RS17705 dc4a3a8f2b6fda2a575bb82cc280799f 225 Pfam PF01895 PhoU domain 16 103 4.8E-17 T 29-03-2018 IPR026022 PhoU domain SMALA_RS17705 dc4a3a8f2b6fda2a575bb82cc280799f 225 Pfam PF01895 PhoU domain 121 204 1.5E-12 T 29-03-2018 IPR026022 PhoU domain SMALA_RS17705 dc4a3a8f2b6fda2a575bb82cc280799f 225 Gene3D G3DSA:1.20.58.220 1 106 4.7E-22 T 29-03-2018 SMALA_RS04905 0f4b16648482d6facf41e63d6cd46d20 210 SUPERFAMILY SSF46689 7 91 1.8E-19 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS04905 0f4b16648482d6facf41e63d6cd46d20 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 67 1.2E-15 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS04905 0f4b16648482d6facf41e63d6cd46d20 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 8.1E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS04905 0f4b16648482d6facf41e63d6cd46d20 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 8.1E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS04905 0f4b16648482d6facf41e63d6cd46d20 210 SUPERFAMILY SSF48498 87 196 1.33E-5 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS04905 0f4b16648482d6facf41e63d6cd46d20 210 Gene3D G3DSA:1.10.357.10 1 210 3.4E-35 T 29-03-2018 SMALA_RS10335 d86408f8ae37434c297ff6d3e534029d 417 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 110 118 8.9E-12 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMALA_RS10335 d86408f8ae37434c297ff6d3e534029d 417 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 271 289 8.9E-12 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMALA_RS10335 d86408f8ae37434c297ff6d3e534029d 417 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 149 173 8.9E-12 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMALA_RS10335 d86408f8ae37434c297ff6d3e534029d 417 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 17 39 8.9E-12 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMALA_RS10335 d86408f8ae37434c297ff6d3e534029d 417 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 236 257 8.9E-12 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMALA_RS10335 d86408f8ae37434c297ff6d3e534029d 417 Gene3D G3DSA:3.50.50.60 30 138 1.0E-14 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS10335 d86408f8ae37434c297ff6d3e534029d 417 SUPERFAMILY SSF55424 326 415 8.38E-29 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SMALA_RS10335 d86408f8ae37434c297ff6d3e534029d 417 Gene3D G3DSA:3.50.50.60 2 29 0.0013 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS10335 d86408f8ae37434c297ff6d3e534029d 417 SUPERFAMILY SSF51905 9 287 6.48E-37 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS10335 d86408f8ae37434c297ff6d3e534029d 417 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 18 37 6.6E-23 T 29-03-2018 SMALA_RS10335 d86408f8ae37434c297ff6d3e534029d 417 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 109 127 6.6E-23 T 29-03-2018 SMALA_RS10335 d86408f8ae37434c297ff6d3e534029d 417 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 234 250 6.6E-23 T 29-03-2018 SMALA_RS10335 d86408f8ae37434c297ff6d3e534029d 417 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 153 171 6.6E-23 T 29-03-2018 SMALA_RS10335 d86408f8ae37434c297ff6d3e534029d 417 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 261 283 6.6E-23 T 29-03-2018 SMALA_RS10335 d86408f8ae37434c297ff6d3e534029d 417 Gene3D G3DSA:3.30.390.30 327 417 7.6E-34 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SMALA_RS10335 d86408f8ae37434c297ff6d3e534029d 417 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 17 302 1.9E-53 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS10335 d86408f8ae37434c297ff6d3e534029d 417 Gene3D G3DSA:3.40.50.720 139 302 1.1E-31 T 29-03-2018 SMALA_RS10335 d86408f8ae37434c297ff6d3e534029d 417 Pfam PF14759 Reductase C-terminal 332 415 9.3E-28 T 29-03-2018 IPR028202 Reductase, C-terminal SMALA_RS05950 fe34757218126ff12f719eab0470b7ff 191 SUPERFAMILY SSF52821 4 109 3.54E-26 T 29-03-2018 IPR001763 Rhodanese-like domain SMALA_RS05950 fe34757218126ff12f719eab0470b7ff 191 Pfam PF00581 Rhodanese-like domain 12 100 2.3E-10 T 29-03-2018 IPR001763 Rhodanese-like domain SMALA_RS05950 fe34757218126ff12f719eab0470b7ff 191 Gene3D G3DSA:3.40.250.10 2 114 6.7E-24 T 29-03-2018 IPR001763 Rhodanese-like domain SMALA_RS05950 fe34757218126ff12f719eab0470b7ff 191 Pfam PF11127 Protein of unknown function (DUF2892) 118 172 8.0E-11 T 29-03-2018 IPR021309 Protein of unknown function DUF2892 SMALA_RS05950 fe34757218126ff12f719eab0470b7ff 191 SMART SM00450 8 105 1.5E-14 T 29-03-2018 IPR001763 Rhodanese-like domain SMALA_RS05785 a3873c06d298a3a6080b9d7862e1448b 341 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 59 119 9.5E-7 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS05785 a3873c06d298a3a6080b9d7862e1448b 341 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 175 196 - T 29-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 SMALA_RS05785 a3873c06d298a3a6080b9d7862e1448b 341 Gene3D G3DSA:3.90.180.10 9 172 1.1E-42 T 29-03-2018 SMALA_RS05785 a3873c06d298a3a6080b9d7862e1448b 341 SUPERFAMILY SSF50129 33 180 1.46E-37 T 29-03-2018 IPR011032 GroES-like SMALA_RS05785 a3873c06d298a3a6080b9d7862e1448b 341 SMART SM00829 42 338 8.7E-45 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS05785 a3873c06d298a3a6080b9d7862e1448b 341 Gene3D G3DSA:3.40.50.720 173 312 4.3E-30 T 29-03-2018 SMALA_RS05785 a3873c06d298a3a6080b9d7862e1448b 341 SUPERFAMILY SSF51735 147 305 7.21E-39 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS05785 a3873c06d298a3a6080b9d7862e1448b 341 Pfam PF13602 Zinc-binding dehydrogenase 217 338 1.1E-27 T 29-03-2018 SMALA_RS08055 294eb9146748df18a4484a93f1cf12ff 269 SUPERFAMILY SSF81342 34 233 4.0E-29 T 29-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 SMALA_RS08055 294eb9146748df18a4484a93f1cf12ff 269 Pfam PF01292 Prokaryotic cytochrome b561 39 204 2.2E-13 T 29-03-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 SMALA_RS08055 294eb9146748df18a4484a93f1cf12ff 269 Gene3D G3DSA:1.20.950.20 32 240 6.7E-36 T 29-03-2018 SMALA_RS18040 1f19c37d8a02786aea574872f6463047 340 SUPERFAMILY SSF53335 7 330 5.82E-41 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS18040 1f19c37d8a02786aea574872f6463047 340 Pfam PF02636 Putative S-adenosyl-L-methionine-dependent methyltransferase 59 267 4.5E-13 T 29-03-2018 IPR003788 Protein arginine methyltransferase NDUFAF7 Reactome: R-HSA-6799198 SMALA_RS29425 cf480716ba76855612acf71007a10b21 283 SUPERFAMILY SSF53474 32 270 1.2E-26 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS29425 cf480716ba76855612acf71007a10b21 283 Gene3D G3DSA:3.40.50.1820 20 272 3.2E-26 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS29425 cf480716ba76855612acf71007a10b21 283 Pfam PF12697 Alpha/beta hydrolase family 35 262 1.2E-11 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS12850 ee40d8b68880b421d83a925b5ca42b27 63 Pfam PF07411 Domain of unknown function (DUF1508) 10 57 6.6E-25 T 29-03-2018 IPR010879 Domain of unknown function DUF1508 SMALA_RS12850 ee40d8b68880b421d83a925b5ca42b27 63 Gene3D G3DSA:3.30.160.160 5 48 1.8E-18 T 29-03-2018 IPR010879 Domain of unknown function DUF1508 SMALA_RS12850 ee40d8b68880b421d83a925b5ca42b27 63 SUPERFAMILY SSF160113 1 57 1.44E-21 T 29-03-2018 IPR010879 Domain of unknown function DUF1508 SMALA_RS02865 9f4dc1e1c23bffb836bed58e06d70c8a 320 SUPERFAMILY SSF53474 54 315 9.59E-48 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS02865 9f4dc1e1c23bffb836bed58e06d70c8a 320 Gene3D G3DSA:3.40.50.1820 1 318 1.5E-41 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS02865 9f4dc1e1c23bffb836bed58e06d70c8a 320 Pfam PF07859 alpha/beta hydrolase fold 90 296 7.4E-46 T 29-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 SMALA_RS25810 28667bf670eee3d3bdd1fc791c935585 221 SUPERFAMILY SSF53335 19 220 2.19E-36 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS25810 28667bf670eee3d3bdd1fc791c935585 221 Pfam PF01596 O-methyltransferase 46 217 2.2E-23 T 29-03-2018 IPR002935 O-methyltransferase, family 3 GO:0008171 SMALA_RS25810 28667bf670eee3d3bdd1fc791c935585 221 Gene3D G3DSA:3.40.50.150 12 221 1.9E-36 T 29-03-2018 SMALA_RS36795 a9922eb975f6cf2034232cea002d2e72 544 Gene3D G3DSA:3.30.300.30 435 544 2.1E-29 T 29-03-2018 SMALA_RS36795 a9922eb975f6cf2034232cea002d2e72 544 Pfam PF13193 AMP-binding enzyme C-terminal domain 450 528 4.1E-24 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS36795 a9922eb975f6cf2034232cea002d2e72 544 Gene3D G3DSA:2.30.38.10 343 434 3.5E-18 T 29-03-2018 SMALA_RS36795 a9922eb975f6cf2034232cea002d2e72 544 Pfam PF00501 AMP-binding enzyme 28 440 3.0E-72 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS36795 a9922eb975f6cf2034232cea002d2e72 544 Gene3D G3DSA:3.40.50.980 18 191 2.9E-31 T 29-03-2018 SMALA_RS36795 a9922eb975f6cf2034232cea002d2e72 544 SUPERFAMILY SSF56801 27 537 4.84E-133 T 29-03-2018 SMALA_RS36795 a9922eb975f6cf2034232cea002d2e72 544 Gene3D G3DSA:3.40.50.980 192 342 2.6E-30 T 29-03-2018 SMALA_RS41580 bd2e55870701d625870e7bb6bd7ee64e 668 SUPERFAMILY SSF56801 38 636 9.29E-124 T 29-03-2018 SMALA_RS41580 bd2e55870701d625870e7bb6bd7ee64e 668 Gene3D G3DSA:3.40.50.980 285 446 2.1E-23 T 29-03-2018 SMALA_RS41580 bd2e55870701d625870e7bb6bd7ee64e 668 Gene3D G3DSA:3.30.300.30 533 659 1.1E-12 T 29-03-2018 SMALA_RS41580 bd2e55870701d625870e7bb6bd7ee64e 668 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 47 102 4.4E-13 T 29-03-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 SMALA_RS41580 bd2e55870701d625870e7bb6bd7ee64e 668 TIGRFAM TIGR01217 ac_ac_CoA_syn: acetoacetate-CoA ligase 4 662 1.7E-288 T 29-03-2018 IPR005914 Acetoacetyl-CoA synthase GO:0006629|GO:0030729 KEGG: 00280+6.2.1.16|KEGG: 00650+6.2.1.16|Reactome: R-HSA-77111 SMALA_RS41580 bd2e55870701d625870e7bb6bd7ee64e 668 Gene3D G3DSA:3.40.50.980 98 284 3.4E-34 T 29-03-2018 SMALA_RS41580 bd2e55870701d625870e7bb6bd7ee64e 668 ProSitePatterns PS00455 Putative AMP-binding domain signature. 278 289 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS41580 bd2e55870701d625870e7bb6bd7ee64e 668 Pfam PF00501 AMP-binding enzyme 111 535 1.2E-47 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS41580 bd2e55870701d625870e7bb6bd7ee64e 668 Pfam PF13193 AMP-binding enzyme C-terminal domain 548 623 5.7E-8 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS30040 ce7419170911624f45d693c719ffc8a7 371 Gene3D G3DSA:2.70.50.50 48 242 1.9E-52 T 29-03-2018 SMALA_RS30040 ce7419170911624f45d693c719ffc8a7 371 ProSitePatterns PS00561 CBM2a (carbohydrate-binding type-2) domain signature. 339 352 - T 29-03-2018 IPR018366 Carbohydrate-binding type-2, conserved site GO:0004553|GO:0005975|GO:0030246 SMALA_RS30040 ce7419170911624f45d693c719ffc8a7 371 SUPERFAMILY SSF81296 48 243 2.1E-42 T 29-03-2018 IPR014756 Immunoglobulin E-set SMALA_RS30040 ce7419170911624f45d693c719ffc8a7 371 SMART SM00637 274 368 1.1E-30 T 29-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 SMALA_RS30040 ce7419170911624f45d693c719ffc8a7 371 Gene3D G3DSA:2.60.40.290 265 371 7.4E-32 T 29-03-2018 SMALA_RS30040 ce7419170911624f45d693c719ffc8a7 371 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 48 239 1.4E-39 T 29-03-2018 IPR004302 Cellulose/chitin-binding protein, N-terminal SMALA_RS30040 ce7419170911624f45d693c719ffc8a7 371 SUPERFAMILY SSF49384 269 362 1.26E-28 T 29-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 SMALA_RS30040 ce7419170911624f45d693c719ffc8a7 371 Pfam PF00553 Cellulose binding domain 274 360 9.8E-26 T 29-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 SMALA_RS36355 1879b7df1b57759bf1005020330a718f 581 Pfam PF14520 Helix-hairpin-helix domain 92 144 1.1E-8 T 29-03-2018 SMALA_RS36355 1879b7df1b57759bf1005020330a718f 581 SUPERFAMILY SSF81301 156 316 2.89E-43 T 29-03-2018 SMALA_RS36355 1879b7df1b57759bf1005020330a718f 581 SUPERFAMILY SSF89550 339 574 9.29E-51 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 SMALA_RS36355 1879b7df1b57759bf1005020330a718f 581 SMART SM00278 92 111 220.0 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 SMALA_RS36355 1879b7df1b57759bf1005020330a718f 581 SMART SM00278 52 71 140.0 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 SMALA_RS36355 1879b7df1b57759bf1005020330a718f 581 SMART SM00278 127 146 35.0 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 SMALA_RS36355 1879b7df1b57759bf1005020330a718f 581 SUPERFAMILY SSF47802 5 84 1.96E-14 T 29-03-2018 IPR010996 DNA polymerase beta-like, N-terminal domain SMALA_RS36355 1879b7df1b57759bf1005020330a718f 581 Pfam PF14716 Helix-hairpin-helix domain 5 72 7.4E-18 T 29-03-2018 IPR010996 DNA polymerase beta-like, N-terminal domain SMALA_RS36355 1879b7df1b57759bf1005020330a718f 581 Gene3D G3DSA:3.30.460.10 156 246 3.4E-28 T 29-03-2018 SMALA_RS36355 1879b7df1b57759bf1005020330a718f 581 SMART SM00481 340 420 5.9E-11 T 29-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal SMALA_RS36355 1879b7df1b57759bf1005020330a718f 581 SMART SM00483 3 316 1.6E-20 T 29-03-2018 IPR002054 DNA-directed DNA polymerase X GO:0003677|GO:0003887 SMALA_RS36355 1879b7df1b57759bf1005020330a718f 581 PRINTS PR00870 DNA-polymerase family X pol beta-like signature 239 247 2.4E-9 T 29-03-2018 IPR002008 DNA polymerase family X, beta-like GO:0003677|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMALA_RS36355 1879b7df1b57759bf1005020330a718f 581 PRINTS PR00870 DNA-polymerase family X pol beta-like signature 254 261 2.4E-9 T 29-03-2018 IPR002008 DNA polymerase family X, beta-like GO:0003677|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMALA_RS36355 1879b7df1b57759bf1005020330a718f 581 PRINTS PR00870 DNA-polymerase family X pol beta-like signature 298 315 2.4E-9 T 29-03-2018 IPR002008 DNA polymerase family X, beta-like GO:0003677|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMALA_RS36355 1879b7df1b57759bf1005020330a718f 581 PRINTS PR00870 DNA-polymerase family X pol beta-like signature 59 76 2.4E-9 T 29-03-2018 IPR002008 DNA polymerase family X, beta-like GO:0003677|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMALA_RS36355 1879b7df1b57759bf1005020330a718f 581 Pfam PF14791 DNA polymerase beta thumb 255 316 2.8E-21 T 29-03-2018 IPR029398 DNA polymerase beta, thumb domain SMALA_RS36355 1879b7df1b57759bf1005020330a718f 581 Pfam PF02811 PHP domain 341 431 2.0E-6 T 29-03-2018 IPR004013 PHP domain GO:0003824 SMALA_RS36355 1879b7df1b57759bf1005020330a718f 581 Gene3D G3DSA:3.30.210.10 248 316 1.9E-22 T 29-03-2018 IPR029398 DNA polymerase beta, thumb domain SMALA_RS36355 1879b7df1b57759bf1005020330a718f 581 Pfam PF14792 DNA polymerase beta palm 156 228 7.4E-6 T 29-03-2018 IPR028207 DNA polymerase beta, palm domain SMALA_RS36355 1879b7df1b57759bf1005020330a718f 581 SUPERFAMILY SSF158702 54 148 6.28E-6 T 29-03-2018 SMALA_RS36355 1879b7df1b57759bf1005020330a718f 581 Gene3D G3DSA:1.10.150.110 2 70 1.6E-16 T 29-03-2018 SMALA_RS36355 1879b7df1b57759bf1005020330a718f 581 Gene3D G3DSA:1.10.150.20 99 155 8.0E-12 T 29-03-2018 SMALA_RS36355 1879b7df1b57759bf1005020330a718f 581 Gene3D G3DSA:3.20.20.140 341 567 1.5E-43 T 29-03-2018 SMALA_RS36355 1879b7df1b57759bf1005020330a718f 581 PIRSF PIRSF005047 3 575 7.5E-210 T 29-03-2018 IPR022311 Uncharacterised conserved protein UCP005047, YshC KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMALA_RS36355 1879b7df1b57759bf1005020330a718f 581 Gene3D G3DSA:1.10.150.20 71 98 0.0091 T 29-03-2018 SMALA_RS10795 c77a864b10fb55500e5a0b5197be3e02 269 Gene3D G3DSA:3.60.110.10 1 267 1.2E-60 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMALA_RS10795 c77a864b10fb55500e5a0b5197be3e02 269 Pfam PF00795 Carbon-nitrogen hydrolase 4 255 1.9E-33 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMALA_RS10795 c77a864b10fb55500e5a0b5197be3e02 269 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 140 160 - T 29-03-2018 IPR001110 Uncharacterised protein family UPF0012, conserved site SMALA_RS10795 c77a864b10fb55500e5a0b5197be3e02 269 SUPERFAMILY SSF56317 3 263 9.42E-61 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMALA_RS01600 0edc379fd31c4af1b0bb65ebe927276a 3647 SUPERFAMILY SSF101173 14 48 7.59E-6 T 29-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 SMALA_RS01600 0edc379fd31c4af1b0bb65ebe927276a 3647 SUPERFAMILY SSF47336 1713 1829 3.14E-25 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS01600 0edc379fd31c4af1b0bb65ebe927276a 3647 SUPERFAMILY SSF55048 704 769 1.96E-13 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS01600 0edc379fd31c4af1b0bb65ebe927276a 3647 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1975 1991 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS01600 0edc379fd31c4af1b0bb65ebe927276a 3647 SMART SM00826 2707 2873 4.6E-87 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS01600 0edc379fd31c4af1b0bb65ebe927276a 3647 SMART SM00826 946 1108 1.2E-70 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS01600 0edc379fd31c4af1b0bb65ebe927276a 3647 Pfam PF00550 Phosphopantetheine attachment site 1721 1787 1.1E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS01600 0edc379fd31c4af1b0bb65ebe927276a 3647 Pfam PF00550 Phosphopantetheine attachment site 3492 3558 4.0E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS01600 0edc379fd31c4af1b0bb65ebe927276a 3647 SMART SM01294 3491 3558 1.3E-5 T 29-03-2018 SMALA_RS01600 0edc379fd31c4af1b0bb65ebe927276a 3647 SMART SM01294 1720 1787 7.5E-7 T 29-03-2018 SMALA_RS01600 0edc379fd31c4af1b0bb65ebe927276a 3647 Pfam PF08659 KR domain 3199 3378 1.0E-58 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS01600 0edc379fd31c4af1b0bb65ebe927276a 3647 Pfam PF08659 KR domain 1432 1611 2.0E-54 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS01600 0edc379fd31c4af1b0bb65ebe927276a 3647 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2191 2311 2.9E-13 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS01600 0edc379fd31c4af1b0bb65ebe927276a 3647 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 426 546 4.2E-14 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS01600 0edc379fd31c4af1b0bb65ebe927276a 3647 SUPERFAMILY SSF53901 45 421 9.26E-101 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS01600 0edc379fd31c4af1b0bb65ebe927276a 3647 SUPERFAMILY SSF52151 2345 2465 7.59E-75 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS01600 0edc379fd31c4af1b0bb65ebe927276a 3647 SUPERFAMILY SSF52151 2527 2635 7.59E-75 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS01600 0edc379fd31c4af1b0bb65ebe927276a 3647 Gene3D G3DSA:3.40.47.10 1813 2074 2.8E-88 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS01600 0edc379fd31c4af1b0bb65ebe927276a 3647 Gene3D G3DSA:3.40.47.10 40 310 3.3E-89 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS01600 0edc379fd31c4af1b0bb65ebe927276a 3647 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 211 227 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS01600 0edc379fd31c4af1b0bb65ebe927276a 3647 SUPERFAMILY SSF51735 1429 1680 2.01E-39 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS01600 0edc379fd31c4af1b0bb65ebe927276a 3647 Gene3D G3DSA:1.10.1200.10 1711 1812 8.4E-22 T 29-03-2018 SMALA_RS01600 0edc379fd31c4af1b0bb65ebe927276a 3647 SUPERFAMILY SSF47336 3483 3569 6.94E-22 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS01600 0edc379fd31c4af1b0bb65ebe927276a 3647 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1814 2062 1.1E-92 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS01600 0edc379fd31c4af1b0bb65ebe927276a 3647 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 48 298 1.9E-94 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS01600 0edc379fd31c4af1b0bb65ebe927276a 3647 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3517 3532 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS01600 0edc379fd31c4af1b0bb65ebe927276a 3647 Pfam PF14765 Polyketide synthase dehydratase 946 1220 1.4E-49 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS01600 0edc379fd31c4af1b0bb65ebe927276a 3647 Pfam PF14765 Polyketide synthase dehydratase 2707 2984 1.5E-57 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS01600 0edc379fd31c4af1b0bb65ebe927276a 3647 SUPERFAMILY SSF53901 1809 2186 4.88E-106 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS01600 0edc379fd31c4af1b0bb65ebe927276a 3647 SUPERFAMILY SSF51735 2993 3184 3.94E-33 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS01600 0edc379fd31c4af1b0bb65ebe927276a 3647 Gene3D G3DSA:3.40.47.10 313 474 3.6E-58 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS01600 0edc379fd31c4af1b0bb65ebe927276a 3647 Gene3D G3DSA:3.40.47.10 2077 2239 2.6E-63 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS01600 0edc379fd31c4af1b0bb65ebe927276a 3647 Gene3D G3DSA:3.30.70.250 716 758 6.5E-19 T 29-03-2018 SMALA_RS01600 0edc379fd31c4af1b0bb65ebe927276a 3647 Gene3D G3DSA:3.30.70.250 2484 2523 1.5E-17 T 29-03-2018 SMALA_RS01600 0edc379fd31c4af1b0bb65ebe927276a 3647 Gene3D G3DSA:3.40.366.10 2524 2652 1.0E-28 T 29-03-2018 SMALA_RS01600 0edc379fd31c4af1b0bb65ebe927276a 3647 Gene3D G3DSA:3.40.50.720 1429 1633 1.5E-41 T 29-03-2018 SMALA_RS01600 0edc379fd31c4af1b0bb65ebe927276a 3647 SUPERFAMILY SSF51735 3195 3422 5.99E-44 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS01600 0edc379fd31c4af1b0bb65ebe927276a 3647 Pfam PF08990 Erythronolide synthase docking 16 41 8.2E-13 T 29-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 SMALA_RS01600 0edc379fd31c4af1b0bb65ebe927276a 3647 SUPERFAMILY SSF55048 2470 2534 1.12E-10 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS01600 0edc379fd31c4af1b0bb65ebe927276a 3647 SUPERFAMILY SSF52151 580 706 1.49E-65 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS01600 0edc379fd31c4af1b0bb65ebe927276a 3647 SUPERFAMILY SSF52151 770 869 1.49E-65 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS01600 0edc379fd31c4af1b0bb65ebe927276a 3647 Gene3D G3DSA:3.40.366.10 2344 2483 1.8E-42 T 29-03-2018 SMALA_RS01600 0edc379fd31c4af1b0bb65ebe927276a 3647 Gene3D G3DSA:3.40.366.10 580 715 6.0E-39 T 29-03-2018 SMALA_RS01600 0edc379fd31c4af1b0bb65ebe927276a 3647 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1432 1612 3.6E-57 T 29-03-2018 SMALA_RS01600 0edc379fd31c4af1b0bb65ebe927276a 3647 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3199 3379 7.7E-60 T 29-03-2018 SMALA_RS01600 0edc379fd31c4af1b0bb65ebe927276a 3647 Gene3D G3DSA:3.40.50.720 3191 3452 3.4E-46 T 29-03-2018 SMALA_RS01600 0edc379fd31c4af1b0bb65ebe927276a 3647 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2348 2640 2.3E-124 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS01600 0edc379fd31c4af1b0bb65ebe927276a 3647 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 584 878 7.4E-118 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS01600 0edc379fd31c4af1b0bb65ebe927276a 3647 Gene3D G3DSA:3.10.129.10 951 1067 0.29 T 29-03-2018 SMALA_RS01600 0edc379fd31c4af1b0bb65ebe927276a 3647 Gene3D G3DSA:3.10.129.10 2709 2837 1.8E-8 T 29-03-2018 SMALA_RS01600 0edc379fd31c4af1b0bb65ebe927276a 3647 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1746 1761 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS01600 0edc379fd31c4af1b0bb65ebe927276a 3647 Pfam PF00698 Acyl transferase domain 582 896 2.7E-84 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS01600 0edc379fd31c4af1b0bb65ebe927276a 3647 Pfam PF00698 Acyl transferase domain 2348 2624 1.5E-52 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS01600 0edc379fd31c4af1b0bb65ebe927276a 3647 Gene3D G3DSA:3.40.366.10 759 885 5.4E-27 T 29-03-2018 SMALA_RS01600 0edc379fd31c4af1b0bb65ebe927276a 3647 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2070 2188 1.3E-44 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS01600 0edc379fd31c4af1b0bb65ebe927276a 3647 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 306 423 4.1E-41 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS01600 0edc379fd31c4af1b0bb65ebe927276a 3647 Gene3D G3DSA:1.10.1200.10 3455 3568 3.4E-19 T 29-03-2018 SMALA_RS01600 0edc379fd31c4af1b0bb65ebe927276a 3647 SMART SM00823 Phosphopantetheine attachment site 3490 3562 4.9E-34 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS01600 0edc379fd31c4af1b0bb65ebe927276a 3647 SMART SM00823 Phosphopantetheine attachment site 1719 1791 8.0E-35 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS01600 0edc379fd31c4af1b0bb65ebe927276a 3647 SUPERFAMILY SSF51735 1226 1415 1.38E-37 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS01600 0edc379fd31c4af1b0bb65ebe927276a 3647 SMART SM00825 Beta-ketoacyl synthase 1816 2241 2.2E-230 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS01600 0edc379fd31c4af1b0bb65ebe927276a 3647 SMART SM00825 Beta-ketoacyl synthase 50 476 1.1E-224 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS25540 f9b29442fa2031217b7d9b235a74be1c 256 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 18 225 7.1E-42 T 29-03-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMALA_RS25540 f9b29442fa2031217b7d9b235a74be1c 256 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 54 62 - T 29-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 SMALA_RS25540 f9b29442fa2031217b7d9b235a74be1c 256 SUPERFAMILY SSF46548 122 231 6.8E-18 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 SMALA_RS25540 f9b29442fa2031217b7d9b235a74be1c 256 Gene3D G3DSA:3.10.20.30 1 104 6.8E-27 T 29-03-2018 IPR012675 Beta-grasp domain SMALA_RS25540 f9b29442fa2031217b7d9b235a74be1c 256 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 8 106 5.6E-26 T 29-03-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMALA_RS25540 f9b29442fa2031217b7d9b235a74be1c 256 Gene3D G3DSA:1.10.1060.10 107 243 3.0E-10 T 29-03-2018 SMALA_RS25540 f9b29442fa2031217b7d9b235a74be1c 256 Pfam PF13183 4Fe-4S dicluster domain 141 222 5.1E-15 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain SMALA_RS25540 f9b29442fa2031217b7d9b235a74be1c 256 SUPERFAMILY SSF54292 6 104 1.97E-22 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SMALA_RS16390 5ff990577139bf62fa3e7f7f85b27b9f 273 Gene3D G3DSA:3.40.50.1580 6 273 1.3E-61 T 29-03-2018 SMALA_RS16390 5ff990577139bf62fa3e7f7f85b27b9f 273 SUPERFAMILY SSF53167 17 273 1.28E-80 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 SMALA_RS16390 5ff990577139bf62fa3e7f7f85b27b9f 273 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 88 129 - T 29-03-2018 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 SMALA_RS16390 5ff990577139bf62fa3e7f7f85b27b9f 273 TIGRFAM TIGR01697 PNPH-PUNA-XAPA: inosine/guanosine/xanthosine phosphorylase family 34 270 5.3E-76 T 29-03-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 SMALA_RS16390 5ff990577139bf62fa3e7f7f85b27b9f 273 PIRSF PIRSF000477 7 273 2.4E-89 T 29-03-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 SMALA_RS16390 5ff990577139bf62fa3e7f7f85b27b9f 273 TIGRFAM TIGR01698 PUNP: purine nucleotide phosphorylase 34 270 5.0E-103 T 29-03-2018 IPR011269 Putative purine nucleotide phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 SMALA_RS16390 5ff990577139bf62fa3e7f7f85b27b9f 273 Pfam PF01048 Phosphorylase superfamily 35 270 2.9E-41 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 SMALA_RS01775 cbdbe778770ad49310eb378b0b2d812d 384 SUPERFAMILY SSF51735 4 161 3.0E-45 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS01775 cbdbe778770ad49310eb378b0b2d812d 384 Gene3D G3DSA:3.30.360.10 144 384 4.2E-48 T 29-03-2018 SMALA_RS01775 cbdbe778770ad49310eb378b0b2d812d 384 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 6 132 2.1E-24 T 29-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 SMALA_RS01775 cbdbe778770ad49310eb378b0b2d812d 384 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 144 274 1.0E-12 T 29-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 SMALA_RS01775 cbdbe778770ad49310eb378b0b2d812d 384 Gene3D G3DSA:3.40.50.720 2 143 5.1E-37 T 29-03-2018 SMALA_RS01775 cbdbe778770ad49310eb378b0b2d812d 384 SUPERFAMILY SSF55347 138 325 1.8E-36 T 29-03-2018 SMALA_RS26340 262c50d0e27065a237407309ffc110b5 205 Gene3D G3DSA:3.40.50.1820 1 193 9.7E-5 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS05900 579e354bceca58ce38f7759dd24e8d95 319 Pfam PF01037 Lrp/AsnC ligand binding domain 238 305 3.1E-8 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain SMALA_RS05900 579e354bceca58ce38f7759dd24e8d95 319 Pfam PF13404 AsnC-type helix-turn-helix domain 171 211 5.8E-11 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMALA_RS05900 579e354bceca58ce38f7759dd24e8d95 319 Pfam PF13404 AsnC-type helix-turn-helix domain 3 43 3.7E-16 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMALA_RS05900 579e354bceca58ce38f7759dd24e8d95 319 Gene3D G3DSA:3.30.70.920 223 314 3.7E-13 T 29-03-2018 SMALA_RS05900 579e354bceca58ce38f7759dd24e8d95 319 Gene3D G3DSA:3.30.70.920 56 144 2.5E-5 T 29-03-2018 SMALA_RS05900 579e354bceca58ce38f7759dd24e8d95 319 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 197 216 4.1E-9 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMALA_RS05900 579e354bceca58ce38f7759dd24e8d95 319 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 186 197 4.1E-9 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMALA_RS05900 579e354bceca58ce38f7759dd24e8d95 319 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 170 186 4.1E-9 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMALA_RS05900 579e354bceca58ce38f7759dd24e8d95 319 SUPERFAMILY SSF46785 3 45 6.35E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS05900 579e354bceca58ce38f7759dd24e8d95 319 SUPERFAMILY SSF46785 170 219 1.06E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS05900 579e354bceca58ce38f7759dd24e8d95 319 Gene3D G3DSA:1.10.10.10 165 217 4.2E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS05900 579e354bceca58ce38f7759dd24e8d95 319 Gene3D G3DSA:1.10.10.10 1 45 1.7E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS05900 579e354bceca58ce38f7759dd24e8d95 319 SUPERFAMILY SSF54909 232 308 8.04E-9 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel SMALA_RS05900 579e354bceca58ce38f7759dd24e8d95 319 SMART SM00344 173 275 5.8E-5 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 SMALA_RS05900 579e354bceca58ce38f7759dd24e8d95 319 SMART SM00344 3 106 8.3E-4 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 SMALA_RS11895 68ad97a3918cd90af15009de00833671 898 Pfam PF15609 Phosphoribosyl transferase 41 228 1.3E-69 T 29-03-2018 SMALA_RS11895 68ad97a3918cd90af15009de00833671 898 Gene3D G3DSA:3.40.50.2020 42 232 6.6E-19 T 29-03-2018 SMALA_RS11895 68ad97a3918cd90af15009de00833671 898 Pfam PF15608 PELOTA RNA binding domain 751 830 6.1E-34 T 29-03-2018 IPR028157 PELOTA RNA-binding domain SMALA_RS11895 68ad97a3918cd90af15009de00833671 898 Pfam PF12500 TRSP domain C terminus to PRTase_2 281 432 6.1E-46 T 29-03-2018 IPR022537 TRSP domain SMALA_RS11895 68ad97a3918cd90af15009de00833671 898 Pfam PF11202 Phosphoribosyl transferase (PRTase) 480 724 6.0E-105 T 29-03-2018 IPR011215 Phosphoribosyl transferase SMALA_RS11895 68ad97a3918cd90af15009de00833671 898 SUPERFAMILY SSF53271 76 197 9.51E-6 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like SMALA_RS42205 510d72a6529d39841240fb0317ee43f8 320 Pfam PF13404 AsnC-type helix-turn-helix domain 2 43 3.3E-10 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMALA_RS42205 510d72a6529d39841240fb0317ee43f8 320 Pfam PF13404 AsnC-type helix-turn-helix domain 179 216 2.5E-9 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMALA_RS42205 510d72a6529d39841240fb0317ee43f8 320 Pfam PF01037 Lrp/AsnC ligand binding domain 244 310 7.5E-6 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain SMALA_RS42205 510d72a6529d39841240fb0317ee43f8 320 Gene3D G3DSA:3.30.70.920 54 148 3.8E-6 T 29-03-2018 SMALA_RS42205 510d72a6529d39841240fb0317ee43f8 320 Gene3D G3DSA:1.10.10.10 161 222 8.5E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS42205 510d72a6529d39841240fb0317ee43f8 320 SMART SM00344 179 280 2.5E-4 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 SMALA_RS42205 510d72a6529d39841240fb0317ee43f8 320 SUPERFAMILY SSF46785 169 225 4.68E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS42205 510d72a6529d39841240fb0317ee43f8 320 SUPERFAMILY SSF54909 238 313 4.65E-7 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel SMALA_RS42205 510d72a6529d39841240fb0317ee43f8 320 Gene3D G3DSA:1.10.10.10 2 53 3.1E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS42205 510d72a6529d39841240fb0317ee43f8 320 Gene3D G3DSA:3.30.70.920 223 317 1.5E-11 T 29-03-2018 SMALA_RS12030 b3b043fe1c65db7300df7f69a38befc5 336 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 14 334 1.5E-110 T 29-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SMALA_RS12030 b3b043fe1c65db7300df7f69a38befc5 336 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 12 335 60.045 T 29-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SMALA_RS12030 b3b043fe1c65db7300df7f69a38befc5 336 Gene3D G3DSA:3.40.47.10 172 336 1.5E-37 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS12030 b3b043fe1c65db7300df7f69a38befc5 336 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 117 194 8.9E-26 T 29-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SMALA_RS12030 b3b043fe1c65db7300df7f69a38befc5 336 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 245 334 1.1E-30 T 29-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SMALA_RS12030 b3b043fe1c65db7300df7f69a38befc5 336 Gene3D G3DSA:3.40.47.10 1 171 9.9E-41 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS12030 b3b043fe1c65db7300df7f69a38befc5 336 SUPERFAMILY SSF53901 11 334 4.7E-62 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS24070 96cfc00f14b23070a968a3f552ac6f78 557 Pfam PF07730 Histidine kinase 210 275 5.4E-17 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMALA_RS24070 96cfc00f14b23070a968a3f552ac6f78 557 Gene3D G3DSA:3.30.565.10 354 487 1.6E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS24070 96cfc00f14b23070a968a3f552ac6f78 557 SUPERFAMILY SSF55874 362 478 8.03E-7 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS00920 f5e6be787eaab02a01ef4b43648d8ed9 307 Gene3D G3DSA:1.10.3720.10 2 277 1.1E-28 T 29-03-2018 SMALA_RS00920 f5e6be787eaab02a01ef4b43648d8ed9 307 SUPERFAMILY SSF161098 68 252 3.92E-17 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS00920 f5e6be787eaab02a01ef4b43648d8ed9 307 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 266 3.9E-15 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS15615 726d71d805ebcac7bb328485be33baf6 750 Gene3D G3DSA:3.90.550.10 1 289 2.3E-39 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS15615 726d71d805ebcac7bb328485be33baf6 750 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 347 715 4.3E-118 T 29-03-2018 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 SMALA_RS15615 726d71d805ebcac7bb328485be33baf6 750 SUPERFAMILY SSF53756 488 714 1.15E-11 T 29-03-2018 SMALA_RS15615 726d71d805ebcac7bb328485be33baf6 750 Pfam PF00535 Glycosyl transferase family 2 5 126 4.4E-28 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 SMALA_RS15615 726d71d805ebcac7bb328485be33baf6 750 SUPERFAMILY SSF53448 2 234 1.54E-44 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS04385 d68946fa233bbc11cea52a8fc254d7df 91 Gene3D G3DSA:1.10.1200.10 9 90 5.2E-10 T 29-03-2018 SMALA_RS04385 d68946fa233bbc11cea52a8fc254d7df 91 Pfam PF00550 Phosphopantetheine attachment site 14 83 5.1E-7 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS04385 d68946fa233bbc11cea52a8fc254d7df 91 SUPERFAMILY SSF47336 18 87 9.95E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS38505 76781e35a0c4575300cc65fd9f14c6b8 391 Gene3D G3DSA:3.30.565.10 261 391 4.5E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS38505 76781e35a0c4575300cc65fd9f14c6b8 391 SUPERFAMILY SSF55874 291 386 1.09E-11 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS38505 76781e35a0c4575300cc65fd9f14c6b8 391 Pfam PF07730 Histidine kinase 191 254 2.3E-16 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMALA_RS06880 344479cf925e3401818f9314c79ac616 2164 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 411 505 2.7E-11 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS06880 344479cf925e3401818f9314c79ac616 2164 SMART SM00829 1413 1718 6.1E-179 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS06880 344479cf925e3401818f9314c79ac616 2164 SUPERFAMILY SSF53901 31 405 1.09E-101 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS06880 344479cf925e3401818f9314c79ac616 2164 SUPERFAMILY SSF55048 691 756 1.12E-13 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS06880 344479cf925e3401818f9314c79ac616 2164 SMART SM01294 2013 2080 1.2E-5 T 29-03-2018 SMALA_RS06880 344479cf925e3401818f9314c79ac616 2164 Gene3D G3DSA:3.40.366.10 748 866 1.4E-21 T 29-03-2018 SMALA_RS06880 344479cf925e3401818f9314c79ac616 2164 Gene3D G3DSA:1.10.1200.10 1994 2092 6.9E-19 T 29-03-2018 SMALA_RS06880 344479cf925e3401818f9314c79ac616 2164 Gene3D G3DSA:3.90.180.10 1398 1721 2.7E-60 T 29-03-2018 SMALA_RS06880 344479cf925e3401818f9314c79ac616 2164 Gene3D G3DSA:3.40.50.720 1723 1980 1.5E-44 T 29-03-2018 SMALA_RS06880 344479cf925e3401818f9314c79ac616 2164 Gene3D G3DSA:3.40.47.10 298 459 3.3E-61 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS06880 344479cf925e3401818f9314c79ac616 2164 Gene3D G3DSA:3.40.47.10 26 295 2.4E-83 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS06880 344479cf925e3401818f9314c79ac616 2164 SMART SM00826 933 1102 3.3E-77 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS06880 344479cf925e3401818f9314c79ac616 2164 Pfam PF14765 Polyketide synthase dehydratase 933 1213 4.8E-54 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS06880 344479cf925e3401818f9314c79ac616 2164 Gene3D G3DSA:3.30.70.250 706 747 1.1E-17 T 29-03-2018 SMALA_RS06880 344479cf925e3401818f9314c79ac616 2164 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 196 212 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS06880 344479cf925e3401818f9314c79ac616 2164 SUPERFAMILY SSF51735 1512 1689 7.65E-37 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS06880 344479cf925e3401818f9314c79ac616 2164 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 1540 1561 - T 29-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 SMALA_RS06880 344479cf925e3401818f9314c79ac616 2164 Gene3D G3DSA:3.40.366.10 564 705 9.1E-39 T 29-03-2018 SMALA_RS06880 344479cf925e3401818f9314c79ac616 2164 SUPERFAMILY SSF47336 2005 2083 3.01E-20 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS06880 344479cf925e3401818f9314c79ac616 2164 SUPERFAMILY SSF51735 1728 1924 5.18E-43 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS06880 344479cf925e3401818f9314c79ac616 2164 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 567 866 1.2E-98 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS06880 344479cf925e3401818f9314c79ac616 2164 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1728 1908 6.6E-56 T 29-03-2018 SMALA_RS06880 344479cf925e3401818f9314c79ac616 2164 Pfam PF00698 Acyl transferase domain 566 884 1.4E-68 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS06880 344479cf925e3401818f9314c79ac616 2164 SUPERFAMILY SSF51735 1221 1393 1.97E-30 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS06880 344479cf925e3401818f9314c79ac616 2164 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2039 2054 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS06880 344479cf925e3401818f9314c79ac616 2164 SUPERFAMILY SSF52151 565 692 3.14E-59 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS06880 344479cf925e3401818f9314c79ac616 2164 SUPERFAMILY SSF52151 757 855 3.14E-59 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS06880 344479cf925e3401818f9314c79ac616 2164 Pfam PF00550 Phosphopantetheine attachment site 2015 2080 5.4E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS06880 344479cf925e3401818f9314c79ac616 2164 Pfam PF08990 Erythronolide synthase docking 2 25 3.1E-8 T 29-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 SMALA_RS06880 344479cf925e3401818f9314c79ac616 2164 Pfam PF08659 KR domain 1728 1906 4.7E-57 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS06880 344479cf925e3401818f9314c79ac616 2164 SMART SM00823 Phosphopantetheine attachment site 2012 2084 1.7E-30 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS06880 344479cf925e3401818f9314c79ac616 2164 Pfam PF13602 Zinc-binding dehydrogenase 1591 1718 2.7E-19 T 29-03-2018 SMALA_RS06880 344479cf925e3401818f9314c79ac616 2164 SUPERFAMILY SSF50129 1427 1545 1.01E-25 T 29-03-2018 IPR011032 GroES-like SMALA_RS06880 344479cf925e3401818f9314c79ac616 2164 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 283 6.3E-89 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS06880 344479cf925e3401818f9314c79ac616 2164 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 291 408 2.6E-43 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS06880 344479cf925e3401818f9314c79ac616 2164 SMART SM00825 Beta-ketoacyl synthase 36 461 1.3E-215 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS23055 c3fd42a1fe3cb95f2e06493a14651a4b 349 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 57 71 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 SMALA_RS23055 c3fd42a1fe3cb95f2e06493a14651a4b 349 Pfam PF00107 Zinc-binding dehydrogenase 185 306 1.6E-19 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMALA_RS23055 c3fd42a1fe3cb95f2e06493a14651a4b 349 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 24 142 6.7E-29 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS23055 c3fd42a1fe3cb95f2e06493a14651a4b 349 Gene3D G3DSA:3.40.50.10730 168 290 5.6E-26 T 29-03-2018 SMALA_RS23055 c3fd42a1fe3cb95f2e06493a14651a4b 349 SMART SM00829 12 347 5.1E-7 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS23055 c3fd42a1fe3cb95f2e06493a14651a4b 349 Gene3D G3DSA:3.90.180.10 1 167 5.0E-51 T 29-03-2018 SMALA_RS23055 c3fd42a1fe3cb95f2e06493a14651a4b 349 SUPERFAMILY SSF51735 147 313 4.32E-36 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS23055 c3fd42a1fe3cb95f2e06493a14651a4b 349 SUPERFAMILY SSF50129 8 181 3.2E-54 T 29-03-2018 IPR011032 GroES-like SMALA_RS28435 711fd9327500dc149dc313838900f03f 189 Pfam PF13508 Acetyltransferase (GNAT) domain 95 162 1.5E-8 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SMALA_RS28435 711fd9327500dc149dc313838900f03f 189 Gene3D G3DSA:3.40.630.30 8 188 7.6E-17 T 29-03-2018 SMALA_RS28435 711fd9327500dc149dc313838900f03f 189 SUPERFAMILY SSF55729 28 181 3.49E-16 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS29580 b08ac7b4d18c3e3cf3976b95815cf331 385 SUPERFAMILY SSF52540 18 134 5.57E-8 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS29580 b08ac7b4d18c3e3cf3976b95815cf331 385 SUPERFAMILY SSF52540 274 312 5.57E-8 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS29580 b08ac7b4d18c3e3cf3976b95815cf331 385 Gene3D G3DSA:3.40.50.300 17 260 2.9E-6 T 29-03-2018 SMALA_RS29580 b08ac7b4d18c3e3cf3976b95815cf331 385 Gene3D G3DSA:3.40.50.300 262 356 0.24 T 29-03-2018 SMALA_RS33235 496f36fb272c6db692d20c1f5bcd7d28 151 SMART SM00344 3 110 1.1E-28 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 SMALA_RS33235 496f36fb272c6db692d20c1f5bcd7d28 151 SUPERFAMILY SSF46785 2 63 3.53E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS33235 496f36fb272c6db692d20c1f5bcd7d28 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 1.0E-10 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMALA_RS33235 496f36fb272c6db692d20c1f5bcd7d28 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 1.0E-10 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMALA_RS33235 496f36fb272c6db692d20c1f5bcd7d28 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 30 1.0E-10 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMALA_RS33235 496f36fb272c6db692d20c1f5bcd7d28 151 ProSitePatterns PS00519 AsnC-type HTH domain signature. 21 47 - T 29-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site SMALA_RS33235 496f36fb272c6db692d20c1f5bcd7d28 151 SUPERFAMILY SSF54909 65 143 4.16E-13 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel SMALA_RS33235 496f36fb272c6db692d20c1f5bcd7d28 151 Pfam PF01037 Lrp/AsnC ligand binding domain 80 139 3.2E-14 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain SMALA_RS33235 496f36fb272c6db692d20c1f5bcd7d28 151 Gene3D G3DSA:1.10.10.10 1 54 3.7E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS33235 496f36fb272c6db692d20c1f5bcd7d28 151 Pfam PF13404 AsnC-type helix-turn-helix domain 3 44 3.4E-16 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMALA_RS33235 496f36fb272c6db692d20c1f5bcd7d28 151 Gene3D G3DSA:3.30.70.920 56 137 3.3E-17 T 29-03-2018 SMALA_RS33665 5cf0784afccb32368a998f87bab2bec4 379 Pfam PF14907 Uncharacterised nucleotidyltransferase 50 323 1.5E-35 T 29-03-2018 SMALA_RS30165 1197c199b3217dceb8c7a0f47c110dea 299 SUPERFAMILY SSF56112 1 270 3.91E-31 T 29-03-2018 IPR011009 Protein kinase-like domain SMALA_RS30165 1197c199b3217dceb8c7a0f47c110dea 299 Gene3D G3DSA:3.90.1200.10 97 292 4.7E-14 T 29-03-2018 SMALA_RS30165 1197c199b3217dceb8c7a0f47c110dea 299 Pfam PF01636 Phosphotransferase enzyme family 31 244 1.5E-12 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase SMALA_RS18960 419876abc13fb54433805624257e4ccf 421 SUPERFAMILY SSF54373 278 366 1.27E-11 T 29-03-2018 SMALA_RS18960 419876abc13fb54433805624257e4ccf 421 Gene3D G3DSA:3.50.50.60 3 421 9.1E-49 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS18960 419876abc13fb54433805624257e4ccf 421 SUPERFAMILY SSF51905 14 64 6.6E-48 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS18960 419876abc13fb54433805624257e4ccf 421 SUPERFAMILY SSF51905 107 278 6.6E-48 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS18960 419876abc13fb54433805624257e4ccf 421 SUPERFAMILY SSF51905 366 421 6.6E-48 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS18960 419876abc13fb54433805624257e4ccf 421 Pfam PF01266 FAD dependent oxidoreductase 15 403 9.4E-63 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 SMALA_RS23360 a777e3846c905b16312478b44cffcc4c 270 SUPERFAMILY SSF53335 6 256 5.32E-46 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS23360 a777e3846c905b16312478b44cffcc4c 270 Pfam PF04072 Leucine carboxyl methyltransferase 15 168 2.3E-10 T 29-03-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 SMALA_RS23360 a777e3846c905b16312478b44cffcc4c 270 Gene3D G3DSA:3.40.50.150 2 208 1.4E-31 T 29-03-2018 SMALA_RS23360 a777e3846c905b16312478b44cffcc4c 270 PIRSF PIRSF028177 1 244 3.0E-58 T 29-03-2018 IPR016874 Tetracenomycin polyketide synthesis O-methyltransferase TcmP GO:0017000|GO:1901106 SMALA_RS26595 90ace75429de16977fac61d138c68a87 282 SMART SM00641 77 186 1.7E-50 T 29-03-2018 IPR018077 Glycoside hydrolase, family 25 subgroup SMALA_RS26595 90ace75429de16977fac61d138c68a87 282 Gene3D G3DSA:3.20.20.80 59 282 8.6E-65 T 29-03-2018 SMALA_RS26595 90ace75429de16977fac61d138c68a87 282 ProSitePatterns PS00953 Glycosyl hydrolases family 25 active sites signature. 81 114 - T 29-03-2018 IPR008270 Glycoside hydrolase, family 25, active site GO:0003796|GO:0009253|GO:0016998 SMALA_RS26595 90ace75429de16977fac61d138c68a87 282 SUPERFAMILY SSF51445 77 281 3.44E-65 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS26595 90ace75429de16977fac61d138c68a87 282 Pfam PF01183 Glycosyl hydrolases family 25 80 264 8.3E-53 T 29-03-2018 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 SMALA_RS05780 3d5121c44db9eea507167865e6d8d5ce 338 Pfam PF01965 DJ-1/PfpI family 10 176 7.1E-17 T 29-03-2018 IPR002818 DJ-1/PfpI SMALA_RS05780 3d5121c44db9eea507167865e6d8d5ce 338 Gene3D G3DSA:3.40.50.880 6 233 2.7E-58 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS05780 3d5121c44db9eea507167865e6d8d5ce 338 SUPERFAMILY SSF46689 268 318 1.43E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS05780 3d5121c44db9eea507167865e6d8d5ce 338 SUPERFAMILY SSF52317 10 197 6.36E-46 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS05780 3d5121c44db9eea507167865e6d8d5ce 338 SUPERFAMILY SSF46689 221 265 4.48E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS05780 3d5121c44db9eea507167865e6d8d5ce 338 Gene3D G3DSA:1.10.10.60 234 269 2.0E-13 T 29-03-2018 SMALA_RS05780 3d5121c44db9eea507167865e6d8d5ce 338 SMART SM00342 231 314 4.9E-27 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS05780 3d5121c44db9eea507167865e6d8d5ce 338 Pfam PF12833 Helix-turn-helix domain 237 315 7.2E-22 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS05780 3d5121c44db9eea507167865e6d8d5ce 338 Gene3D G3DSA:1.10.10.60 270 322 3.1E-12 T 29-03-2018 SMALA_RS29835 aafd965d6d6141e639a8b5619f56787d 219 Pfam PF00196 Bacterial regulatory proteins, luxR family 158 212 2.2E-16 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS29835 aafd965d6d6141e639a8b5619f56787d 219 Pfam PF00072 Response regulator receiver domain 24 116 1.8E-5 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS29835 aafd965d6d6141e639a8b5619f56787d 219 Gene3D G3DSA:3.40.50.2300 14 124 1.3E-10 T 29-03-2018 SMALA_RS29835 aafd965d6d6141e639a8b5619f56787d 219 SUPERFAMILY SSF52172 17 121 1.1E-11 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS29835 aafd965d6d6141e639a8b5619f56787d 219 ProSitePatterns PS00622 LuxR-type HTH domain signature. 172 199 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS29835 aafd965d6d6141e639a8b5619f56787d 219 SUPERFAMILY SSF46894 145 218 1.73E-18 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS29835 aafd965d6d6141e639a8b5619f56787d 219 Gene3D G3DSA:1.10.10.10 156 218 1.3E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS29835 aafd965d6d6141e639a8b5619f56787d 219 SMART SM00421 155 212 1.0E-21 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS29835 aafd965d6d6141e639a8b5619f56787d 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 188 2.8E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS29835 aafd965d6d6141e639a8b5619f56787d 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 188 200 2.8E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS29835 aafd965d6d6141e639a8b5619f56787d 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 172 2.8E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS11615 41ba24f8bc0ca9928fed236bf01601ff 392 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 1 289 3.8E-56 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS11615 41ba24f8bc0ca9928fed236bf01601ff 392 SUPERFAMILY SSF51905 138 297 1.7E-28 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS11615 41ba24f8bc0ca9928fed236bf01601ff 392 Pfam PF14759 Reductase C-terminal 310 381 4.0E-12 T 29-03-2018 IPR028202 Reductase, C-terminal SMALA_RS11615 41ba24f8bc0ca9928fed236bf01601ff 392 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 259 266 2.6E-19 T 29-03-2018 SMALA_RS11615 41ba24f8bc0ca9928fed236bf01601ff 392 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 99 108 2.6E-19 T 29-03-2018 SMALA_RS11615 41ba24f8bc0ca9928fed236bf01601ff 392 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 139 164 2.6E-19 T 29-03-2018 SMALA_RS11615 41ba24f8bc0ca9928fed236bf01601ff 392 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 221 235 2.6E-19 T 29-03-2018 SMALA_RS11615 41ba24f8bc0ca9928fed236bf01601ff 392 Gene3D G3DSA:3.40.50.720 122 296 6.1E-29 T 29-03-2018 SMALA_RS11615 41ba24f8bc0ca9928fed236bf01601ff 392 SUPERFAMILY SSF55424 303 380 1.28E-18 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SMALA_RS11615 41ba24f8bc0ca9928fed236bf01601ff 392 Gene3D G3DSA:3.30.390.30 305 387 4.1E-21 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SMALA_RS11615 41ba24f8bc0ca9928fed236bf01601ff 392 SUPERFAMILY SSF51905 1 184 2.16E-42 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS11615 41ba24f8bc0ca9928fed236bf01601ff 392 Gene3D G3DSA:3.50.50.60 1 121 2.2E-16 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS11615 41ba24f8bc0ca9928fed236bf01601ff 392 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 244 266 8.1E-19 T 29-03-2018 SMALA_RS11615 41ba24f8bc0ca9928fed236bf01601ff 392 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 139 157 8.1E-19 T 29-03-2018 SMALA_RS11615 41ba24f8bc0ca9928fed236bf01601ff 392 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 96 114 8.1E-19 T 29-03-2018 SMALA_RS11615 41ba24f8bc0ca9928fed236bf01601ff 392 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 220 236 8.1E-19 T 29-03-2018 SMALA_RS08705 01c4635f124947754e913250f0b3bc22 371 ProSitePatterns PS00836 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 1. 4 30 - T 29-03-2018 IPR008142 Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 GO:0016491|GO:0055114 Reactome: R-HSA-71403 SMALA_RS08705 01c4635f124947754e913250f0b3bc22 371 TIGRFAM TIGR00518 alaDH: alanine dehydrogenase 2 359 2.1E-173 T 29-03-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 SMALA_RS08705 01c4635f124947754e913250f0b3bc22 371 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 137 2.4E-47 T 29-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal SMALA_RS08705 01c4635f124947754e913250f0b3bc22 371 SUPERFAMILY SSF51735 137 303 4.19E-48 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS08705 01c4635f124947754e913250f0b3bc22 371 SMART SM01002 149 297 2.9E-85 T 29-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain SMALA_RS08705 01c4635f124947754e913250f0b3bc22 371 SUPERFAMILY SSF52283 305 359 5.61E-66 T 29-03-2018 SMALA_RS08705 01c4635f124947754e913250f0b3bc22 371 SUPERFAMILY SSF52283 2 137 5.61E-66 T 29-03-2018 SMALA_RS08705 01c4635f124947754e913250f0b3bc22 371 Gene3D G3DSA:3.40.50.720 1 186 6.2E-44 T 29-03-2018 SMALA_RS08705 01c4635f124947754e913250f0b3bc22 371 Gene3D G3DSA:3.40.50.720 187 371 1.8E-46 T 29-03-2018 SMALA_RS08705 01c4635f124947754e913250f0b3bc22 371 SMART SM01003 4 137 8.5E-79 T 29-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal SMALA_RS08705 01c4635f124947754e913250f0b3bc22 371 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 141 352 1.4E-81 T 29-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain SMALA_RS08705 01c4635f124947754e913250f0b3bc22 371 PIRSF PIRSF000183 1 370 4.3E-166 T 29-03-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 SMALA_RS24170 1cdf051a144f142f0e9deaabb19af08d 455 SUPERFAMILY SSF103473 13 439 1.83E-76 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS24170 1cdf051a144f142f0e9deaabb19af08d 455 Pfam PF07690 Major Facilitator Superfamily 29 400 2.0E-42 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS24170 1cdf051a144f142f0e9deaabb19af08d 455 Gene3D G3DSA:1.20.1250.20 244 449 7.7E-19 T 29-03-2018 SMALA_RS24170 1cdf051a144f142f0e9deaabb19af08d 455 Gene3D G3DSA:1.20.1250.20 13 225 5.8E-37 T 29-03-2018 SMALA_RS15420 e737b123e97c1b9e3a9083df46496a4a 320 Gene3D G3DSA:3.40.190.10 74 181 1.3E-5 T 29-03-2018 SMALA_RS15420 e737b123e97c1b9e3a9083df46496a4a 320 SUPERFAMILY SSF53850 98 298 1.47E-10 T 29-03-2018 SMALA_RS15420 e737b123e97c1b9e3a9083df46496a4a 320 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 66 1.0E-20 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS15420 e737b123e97c1b9e3a9083df46496a4a 320 Gene3D G3DSA:3.40.190.10 182 271 7.2E-8 T 29-03-2018 SMALA_RS15420 e737b123e97c1b9e3a9083df46496a4a 320 Pfam PF03466 LysR substrate binding domain 98 294 6.1E-11 T 29-03-2018 IPR005119 LysR, substrate-binding SMALA_RS15420 e737b123e97c1b9e3a9083df46496a4a 320 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 5.1E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS15420 e737b123e97c1b9e3a9083df46496a4a 320 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 5.1E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS15420 e737b123e97c1b9e3a9083df46496a4a 320 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 5.1E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS15420 e737b123e97c1b9e3a9083df46496a4a 320 SUPERFAMILY SSF46785 5 86 8.55E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS15420 e737b123e97c1b9e3a9083df46496a4a 320 Gene3D G3DSA:1.10.10.10 1 73 1.1E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS21270 4052c81de0f898edac7fbec3dd811ebf 471 Gene3D G3DSA:3.40.50.300 51 433 3.4E-15 T 29-03-2018 SMALA_RS21270 4052c81de0f898edac7fbec3dd811ebf 471 Pfam PF12846 AAA-like domain 69 349 2.0E-13 T 29-03-2018 SMALA_RS21270 4052c81de0f898edac7fbec3dd811ebf 471 SUPERFAMILY SSF52540 40 424 1.13E-34 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS39155 b63d94a9597deed852401291dfeb4802 197 SUPERFAMILY SSF47336 101 183 2.36E-20 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS39155 b63d94a9597deed852401291dfeb4802 197 ProSitePatterns PS00012 Phosphopantetheine attachment site. 135 150 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS39155 b63d94a9597deed852401291dfeb4802 197 Gene3D G3DSA:1.10.1200.10 100 196 1.4E-19 T 29-03-2018 SMALA_RS39155 b63d94a9597deed852401291dfeb4802 197 SMART SM00823 Phosphopantetheine attachment site 108 180 4.2E-26 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS39155 b63d94a9597deed852401291dfeb4802 197 SMART SM01294 109 176 0.0062 T 29-03-2018 SMALA_RS39155 b63d94a9597deed852401291dfeb4802 197 Pfam PF00550 Phosphopantetheine attachment site 110 176 1.0E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS04530 d82e90bb66c084492b5264f7322139d9 344 SMART SM00062 42 256 3.7E-10 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SMALA_RS04530 d82e90bb66c084492b5264f7322139d9 344 Gene3D G3DSA:3.40.190.10 38 140 1.6E-10 T 29-03-2018 SMALA_RS04530 d82e90bb66c084492b5264f7322139d9 344 Gene3D G3DSA:3.40.190.10 141 330 3.8E-34 T 29-03-2018 SMALA_RS04530 d82e90bb66c084492b5264f7322139d9 344 SUPERFAMILY SSF53850 55 270 2.0E-44 T 29-03-2018 SMALA_RS04530 d82e90bb66c084492b5264f7322139d9 344 TIGRFAM TIGR01728 SsuA_fam: ABC transporter, substrate-binding protein, aliphatic sulfonates family 44 326 1.4E-55 T 29-03-2018 IPR010067 Aliphatic sulfonates-binding protein GO:0016020|GO:0042626 SMALA_RS04530 d82e90bb66c084492b5264f7322139d9 344 Pfam PF13379 NMT1-like family 67 258 1.9E-12 T 29-03-2018 SMALA_RS26315 403b430a7bee2715e4f1628570c97749 519 SUPERFAMILY SSF51445 20 337 7.79E-78 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS26315 403b430a7bee2715e4f1628570c97749 519 Gene3D G3DSA:3.20.20.300 16 350 7.1E-83 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SMALA_RS26315 403b430a7bee2715e4f1628570c97749 519 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 40 334 3.8E-73 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SMALA_RS25190 dda699a8b652105fb4d772e24ab8cb7f 499 ProSitePatterns PS00571 Amidases signature. 148 179 - T 29-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 SMALA_RS25190 dda699a8b652105fb4d772e24ab8cb7f 499 Pfam PF01425 Amidase 27 473 1.7E-88 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMALA_RS25190 dda699a8b652105fb4d772e24ab8cb7f 499 Gene3D G3DSA:3.90.1300.10 2 497 3.9E-128 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMALA_RS25190 dda699a8b652105fb4d772e24ab8cb7f 499 SUPERFAMILY SSF75304 4 390 8.24E-122 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMALA_RS25190 dda699a8b652105fb4d772e24ab8cb7f 499 SUPERFAMILY SSF75304 426 482 8.24E-122 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMALA_RS10205 cc29056946c24dedaa8255cc0c66a183 410 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 6 337 38.737 T 29-03-2018 IPR000158 Cell division protein FtsZ GO:0005525 SMALA_RS10205 cc29056946c24dedaa8255cc0c66a183 410 ProSitePatterns PS01134 FtsZ protein signature 1. 41 75 - T 29-03-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 SMALA_RS10205 cc29056946c24dedaa8255cc0c66a183 410 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 11 170 1.1E-36 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 SMALA_RS10205 cc29056946c24dedaa8255cc0c66a183 410 SUPERFAMILY SSF55307 201 315 5.95E-44 T 29-03-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 SMALA_RS10205 cc29056946c24dedaa8255cc0c66a183 410 SMART SM00864 10 202 7.1E-108 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 SMALA_RS10205 cc29056946c24dedaa8255cc0c66a183 410 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 7 314 7.3E-127 T 29-03-2018 IPR000158 Cell division protein FtsZ GO:0005525 SMALA_RS10205 cc29056946c24dedaa8255cc0c66a183 410 SUPERFAMILY SSF52490 9 205 1.28E-66 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 SMALA_RS10205 cc29056946c24dedaa8255cc0c66a183 410 Gene3D G3DSA:3.30.1330.20 212 319 2.6E-46 T 29-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 SMALA_RS10205 cc29056946c24dedaa8255cc0c66a183 410 Pfam PF12327 FtsZ family, C-terminal domain 219 313 2.5E-35 T 29-03-2018 IPR024757 Cell division protein FtsZ, C-terminal SMALA_RS10205 cc29056946c24dedaa8255cc0c66a183 410 PRINTS PR00423 Cell division protein FtsZ signature 95 115 1.5E-51 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 SMALA_RS10205 cc29056946c24dedaa8255cc0c66a183 410 PRINTS PR00423 Cell division protein FtsZ signature 209 230 1.5E-51 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 SMALA_RS10205 cc29056946c24dedaa8255cc0c66a183 410 PRINTS PR00423 Cell division protein FtsZ signature 186 208 1.5E-51 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 SMALA_RS10205 cc29056946c24dedaa8255cc0c66a183 410 PRINTS PR00423 Cell division protein FtsZ signature 123 144 1.5E-51 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 SMALA_RS10205 cc29056946c24dedaa8255cc0c66a183 410 SMART SM00865 204 321 5.6E-57 T 29-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 SMALA_RS10205 cc29056946c24dedaa8255cc0c66a183 410 Gene3D G3DSA:3.40.50.1440 6 211 7.1E-40 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 SMALA_RS10205 cc29056946c24dedaa8255cc0c66a183 410 ProSitePatterns PS01135 FtsZ protein signature 2. 94 115 - T 29-03-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 SMALA_RS38420 d899f2870fc80dc56b08103a817c9a23 642 Gene3D G3DSA:3.30.70.1450 533 635 0.0015 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 SMALA_RS38420 d899f2870fc80dc56b08103a817c9a23 642 Pfam PF02254 TrkA-N domain 393 501 3.6E-20 T 29-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 SMALA_RS38420 d899f2870fc80dc56b08103a817c9a23 642 Pfam PF02254 TrkA-N domain 80 148 7.5E-9 T 29-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 SMALA_RS38420 d899f2870fc80dc56b08103a817c9a23 642 SUPERFAMILY SSF51735 78 147 3.84E-11 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS38420 d899f2870fc80dc56b08103a817c9a23 642 Gene3D G3DSA:3.40.50.720 1 153 1.4E-25 T 29-03-2018 SMALA_RS38420 d899f2870fc80dc56b08103a817c9a23 642 Gene3D G3DSA:3.40.50.720 384 506 1.4E-22 T 29-03-2018 SMALA_RS38420 d899f2870fc80dc56b08103a817c9a23 642 SUPERFAMILY SSF51735 389 506 1.52E-22 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS15610 a99cde758f2c49910d43ce31e9740977 669 Gene3D G3DSA:3.90.550.10 4 257 1.5E-45 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS15610 a99cde758f2c49910d43ce31e9740977 669 Pfam PF00535 Glycosyl transferase family 2 10 142 1.3E-32 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 SMALA_RS15610 a99cde758f2c49910d43ce31e9740977 669 SUPERFAMILY SSF53448 7 215 9.57E-47 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS18495 b5b98d4eb406fa769cb6adb829312125 1096 Pfam PF02223 Thymidylate kinase 513 697 4.9E-46 T 29-03-2018 SMALA_RS18495 b5b98d4eb406fa769cb6adb829312125 1096 SUPERFAMILY SSF52540 507 693 5.34E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS18495 b5b98d4eb406fa769cb6adb829312125 1096 Gene3D G3DSA:1.20.1250.20 19 270 0.09 T 29-03-2018 SMALA_RS18495 b5b98d4eb406fa769cb6adb829312125 1096 Gene3D G3DSA:1.20.1250.20 287 481 2.2E-10 T 29-03-2018 SMALA_RS18495 b5b98d4eb406fa769cb6adb829312125 1096 SUPERFAMILY SSF103473 283 470 3.79E-11 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS18495 b5b98d4eb406fa769cb6adb829312125 1096 Gene3D G3DSA:3.40.50.300 482 774 5.7E-61 T 29-03-2018 SMALA_RS18495 b5b98d4eb406fa769cb6adb829312125 1096 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 508 696 3.0E-49 T 29-03-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 SMALA_RS18495 b5b98d4eb406fa769cb6adb829312125 1096 Hamap MF_00165 Thymidylate kinase [tmk]. 509 708 30.388 T 29-03-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 SMALA_RS18495 b5b98d4eb406fa769cb6adb829312125 1096 ProSitePatterns PS01331 Thymidylate kinase signature. 598 610 - T 29-03-2018 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 SMALA_RS00220 1ecc5877fc22083659216f163c28722e 370 SUPERFAMILY SSF103473 109 365 3.01E-35 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS00220 1ecc5877fc22083659216f163c28722e 370 SMART SM01007 15 174 7.9E-11 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal SMALA_RS00220 1ecc5877fc22083659216f163c28722e 370 Gene3D G3DSA:3.40.225.10 9 180 9.8E-24 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal SMALA_RS00220 1ecc5877fc22083659216f163c28722e 370 Pfam PF07690 Major Facilitator Superfamily 173 329 4.5E-13 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS00220 1ecc5877fc22083659216f163c28722e 370 SUPERFAMILY SSF53639 10 112 9.42E-25 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal SMALA_RS00220 1ecc5877fc22083659216f163c28722e 370 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 16 109 2.6E-20 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal SMALA_RS00220 1ecc5877fc22083659216f163c28722e 370 Gene3D G3DSA:1.20.1250.20 181 367 8.2E-24 T 29-03-2018 SMALA_RS06455 9c6352a11861310faaf34e4c5fe7b35c 972 SUPERFAMILY SSF46894 904 964 1.6E-14 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS06455 9c6352a11861310faaf34e4c5fe7b35c 972 Gene3D G3DSA:1.25.40.10 296 474 0.24 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS06455 9c6352a11861310faaf34e4c5fe7b35c 972 Gene3D G3DSA:1.25.40.10 694 883 4.6E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS06455 9c6352a11861310faaf34e4c5fe7b35c 972 Pfam PF13191 AAA ATPase domain 8 215 1.3E-14 T 29-03-2018 SMALA_RS06455 9c6352a11861310faaf34e4c5fe7b35c 972 Gene3D G3DSA:3.40.50.300 2 219 4.6E-6 T 29-03-2018 SMALA_RS06455 9c6352a11861310faaf34e4c5fe7b35c 972 SUPERFAMILY SSF52540 5 59 4.54E-8 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS06455 9c6352a11861310faaf34e4c5fe7b35c 972 SUPERFAMILY SSF52540 163 293 4.54E-8 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS06455 9c6352a11861310faaf34e4c5fe7b35c 972 Gene3D G3DSA:1.10.10.10 901 971 1.1E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS06455 9c6352a11861310faaf34e4c5fe7b35c 972 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 910 924 3.2E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS06455 9c6352a11861310faaf34e4c5fe7b35c 972 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 924 940 3.2E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS06455 9c6352a11861310faaf34e4c5fe7b35c 972 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 940 952 3.2E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS06455 9c6352a11861310faaf34e4c5fe7b35c 972 SMART SM00421 907 964 5.6E-19 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS06455 9c6352a11861310faaf34e4c5fe7b35c 972 Pfam PF00196 Bacterial regulatory proteins, luxR family 910 960 3.3E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS06455 9c6352a11861310faaf34e4c5fe7b35c 972 Gene3D G3DSA:1.25.40.10 496 693 4.6E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS24415 174695db8abea4b7546feff5cff6a733 1095 Gene3D G3DSA:1.25.40.10 718 806 5.8E-13 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS24415 174695db8abea4b7546feff5cff6a733 1095 SMART SM00382 256 404 3.6E-5 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS24415 174695db8abea4b7546feff5cff6a733 1095 Gene3D G3DSA:1.25.40.10 807 925 2.3E-14 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS24415 174695db8abea4b7546feff5cff6a733 1095 PRINTS PR00364 Disease resistance protein signature 436 450 3.4E-6 T 29-03-2018 SMALA_RS24415 174695db8abea4b7546feff5cff6a733 1095 PRINTS PR00364 Disease resistance protein signature 259 274 3.4E-6 T 29-03-2018 SMALA_RS24415 174695db8abea4b7546feff5cff6a733 1095 PRINTS PR00364 Disease resistance protein signature 345 359 3.4E-6 T 29-03-2018 SMALA_RS24415 174695db8abea4b7546feff5cff6a733 1095 Pfam PF00931 NB-ARC domain 253 450 6.5E-6 T 29-03-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207 SMALA_RS24415 174695db8abea4b7546feff5cff6a733 1095 Gene3D G3DSA:1.10.150.200 552 717 0.02 T 29-03-2018 SMALA_RS24415 174695db8abea4b7546feff5cff6a733 1095 Pfam PF13424 Tetratricopeptide repeat 752 823 2.9E-9 T 29-03-2018 SMALA_RS24415 174695db8abea4b7546feff5cff6a733 1095 SUPERFAMILY SSF48452 791 910 1.74E-16 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS24415 174695db8abea4b7546feff5cff6a733 1095 Gene3D G3DSA:1.25.40.10 932 1062 0.0022 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS24415 174695db8abea4b7546feff5cff6a733 1095 Gene3D G3DSA:1.10.10.10 477 550 1.8E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS24415 174695db8abea4b7546feff5cff6a733 1095 SMART SM00028 873 906 5.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS24415 174695db8abea4b7546feff5cff6a733 1095 SMART SM00028 713 746 0.48 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS24415 174695db8abea4b7546feff5cff6a733 1095 SMART SM00028 833 866 16.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS24415 174695db8abea4b7546feff5cff6a733 1095 SMART SM00028 793 826 53.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS24415 174695db8abea4b7546feff5cff6a733 1095 SMART SM00028 753 786 44.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS24415 174695db8abea4b7546feff5cff6a733 1095 SUPERFAMILY SSF52540 228 487 3.57E-32 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS24415 174695db8abea4b7546feff5cff6a733 1095 Gene3D G3DSA:3.40.50.300 210 399 4.9E-17 T 29-03-2018 SMALA_RS24415 174695db8abea4b7546feff5cff6a733 1095 SUPERFAMILY SSF48452 677 823 6.83E-16 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS15680 c0c3be3128612a6ff32679ecdfdd1d42 657 SUPERFAMILY SSF55874 387 556 2.23E-41 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS15680 c0c3be3128612a6ff32679ecdfdd1d42 657 Gene3D G3DSA:1.10.287.130 321 394 1.8E-14 T 29-03-2018 SMALA_RS15680 c0c3be3128612a6ff32679ecdfdd1d42 657 SMART SM00387 444 555 1.3E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS15680 c0c3be3128612a6ff32679ecdfdd1d42 657 SMART SM00304 271 323 5.5E-10 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMALA_RS15680 c0c3be3128612a6ff32679ecdfdd1d42 657 Pfam PF00512 His Kinase A (phospho-acceptor) domain 331 398 3.2E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS15680 c0c3be3128612a6ff32679ecdfdd1d42 657 SMART SM00388 331 398 9.5E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS15680 c0c3be3128612a6ff32679ecdfdd1d42 657 SUPERFAMILY SSF158472 271 319 2.48E-6 T 29-03-2018 SMALA_RS15680 c0c3be3128612a6ff32679ecdfdd1d42 657 PRINTS PR00344 Bacterial sensor protein C-terminal signature 480 494 5.5E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS15680 c0c3be3128612a6ff32679ecdfdd1d42 657 PRINTS PR00344 Bacterial sensor protein C-terminal signature 539 552 5.5E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS15680 c0c3be3128612a6ff32679ecdfdd1d42 657 PRINTS PR00344 Bacterial sensor protein C-terminal signature 498 508 5.5E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS15680 c0c3be3128612a6ff32679ecdfdd1d42 657 PRINTS PR00344 Bacterial sensor protein C-terminal signature 515 533 5.5E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS15680 c0c3be3128612a6ff32679ecdfdd1d42 657 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 445 554 4.9E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS15680 c0c3be3128612a6ff32679ecdfdd1d42 657 SUPERFAMILY SSF47384 314 398 3.34E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS15680 c0c3be3128612a6ff32679ecdfdd1d42 657 Gene3D G3DSA:3.30.565.10 402 558 4.3E-37 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS41870 2b0507e05ff073c53bf6721f0150ff6b 353 Gene3D G3DSA:3.50.50.60 1 137 1.3E-22 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS41870 2b0507e05ff073c53bf6721f0150ff6b 353 SUPERFAMILY SSF51905 12 304 3.63E-29 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS41870 2b0507e05ff073c53bf6721f0150ff6b 353 Gene3D G3DSA:3.50.50.60 238 334 0.036 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS41870 2b0507e05ff073c53bf6721f0150ff6b 353 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 15 294 3.1E-20 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS41870 2b0507e05ff073c53bf6721f0150ff6b 353 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 15 37 1.2E-11 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMALA_RS41870 2b0507e05ff073c53bf6721f0150ff6b 353 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 114 122 1.2E-11 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMALA_RS41870 2b0507e05ff073c53bf6721f0150ff6b 353 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 136 148 1.2E-11 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMALA_RS41870 2b0507e05ff073c53bf6721f0150ff6b 353 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 273 291 1.2E-11 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMALA_RS41870 2b0507e05ff073c53bf6721f0150ff6b 353 Gene3D G3DSA:3.50.50.60 138 237 1.7E-15 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS41870 2b0507e05ff073c53bf6721f0150ff6b 353 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 113 131 7.2E-9 T 29-03-2018 SMALA_RS41870 2b0507e05ff073c53bf6721f0150ff6b 353 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 263 285 7.2E-9 T 29-03-2018 SMALA_RS41870 2b0507e05ff073c53bf6721f0150ff6b 353 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 16 35 7.2E-9 T 29-03-2018 SMALA_RS01540 f2bad9e9e5f67a1d31c3662f183e4e6b 446 TIGRFAM TIGR01426 MGT: glycosyltransferase, MGT family 187 417 1.5E-35 T 29-03-2018 IPR006326 UDP-glycosyltransferase, MGT GO:0016758|GO:0016999 SMALA_RS01540 f2bad9e9e5f67a1d31c3662f183e4e6b 446 SUPERFAMILY SSF53756 14 418 8.48E-68 T 29-03-2018 SMALA_RS01540 f2bad9e9e5f67a1d31c3662f183e4e6b 446 Gene3D G3DSA:3.40.50.2000 239 403 8.4E-35 T 29-03-2018 SMALA_RS01540 f2bad9e9e5f67a1d31c3662f183e4e6b 446 Gene3D G3DSA:3.40.50.2000 14 238 4.7E-34 T 29-03-2018 SMALA_RS01540 f2bad9e9e5f67a1d31c3662f183e4e6b 446 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 303 398 1.0E-15 T 29-03-2018 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 Reactome: R-HSA-156588 SMALA_RS27050 e5efc78bdf3f9f4d5cccaa723ba13adc 392 PIRSF PIRSF000429 1 390 3.4E-116 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 SMALA_RS27050 e5efc78bdf3f9f4d5cccaa723ba13adc 392 Pfam PF02803 Thiolase, C-terminal domain 267 387 2.4E-43 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 SMALA_RS27050 e5efc78bdf3f9f4d5cccaa723ba13adc 392 SUPERFAMILY SSF53901 268 387 6.14E-35 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS27050 e5efc78bdf3f9f4d5cccaa723ba13adc 392 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 80 98 - T 29-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 SMALA_RS27050 e5efc78bdf3f9f4d5cccaa723ba13adc 392 ProSitePatterns PS00099 Thiolases active site. 370 383 - T 29-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 SMALA_RS27050 e5efc78bdf3f9f4d5cccaa723ba13adc 392 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 3 386 9.6E-137 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 SMALA_RS27050 e5efc78bdf3f9f4d5cccaa723ba13adc 392 Gene3D G3DSA:3.40.47.10 262 386 9.5E-32 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS27050 e5efc78bdf3f9f4d5cccaa723ba13adc 392 ProSitePatterns PS00737 Thiolases signature 2. 335 351 - T 29-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 SMALA_RS27050 e5efc78bdf3f9f4d5cccaa723ba13adc 392 SUPERFAMILY SSF53901 2 266 1.09E-84 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS27050 e5efc78bdf3f9f4d5cccaa723ba13adc 392 Gene3D G3DSA:3.40.47.10 1 261 3.9E-60 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS27050 e5efc78bdf3f9f4d5cccaa723ba13adc 392 Pfam PF00108 Thiolase, N-terminal domain 1 258 2.5E-97 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 SMALA_RS04080 94823bf86cd90998eeaa0ba701667576 359 Gene3D G3DSA:3.40.640.10 31 263 2.0E-32 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS04080 94823bf86cd90998eeaa0ba701667576 359 SUPERFAMILY SSF53383 20 355 1.24E-94 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS04080 94823bf86cd90998eeaa0ba701667576 359 Gene3D G3DSA:3.90.1150.10 264 359 1.9E-28 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS04080 94823bf86cd90998eeaa0ba701667576 359 Pfam PF01212 Beta-eliminating lyase 22 308 1.2E-57 T 29-03-2018 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 SMALA_RS03090 46db70a3b5268bd765681bd1c791d353 813 Gene3D G3DSA:3.60.40.10 437 685 8.6E-40 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS03090 46db70a3b5268bd765681bd1c791d353 813 Gene3D G3DSA:3.30.450.20 15 121 2.5E-12 T 29-03-2018 SMALA_RS03090 46db70a3b5268bd765681bd1c791d353 813 SUPERFAMILY SSF55785 130 246 4.01E-15 T 29-03-2018 IPR000014 PAS domain SMALA_RS03090 46db70a3b5268bd765681bd1c791d353 813 Pfam PF08448 PAS fold 137 248 1.2E-20 T 29-03-2018 IPR013656 PAS fold-4 SMALA_RS03090 46db70a3b5268bd765681bd1c791d353 813 Gene3D G3DSA:3.30.450.40 255 436 8.0E-32 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS03090 46db70a3b5268bd765681bd1c791d353 813 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 132 255 5.2E-9 T 29-03-2018 IPR000014 PAS domain SMALA_RS03090 46db70a3b5268bd765681bd1c791d353 813 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 17 120 1.8E-9 T 29-03-2018 IPR000014 PAS domain SMALA_RS03090 46db70a3b5268bd765681bd1c791d353 813 SMART SM00091 10 76 0.28 T 29-03-2018 IPR000014 PAS domain SMALA_RS03090 46db70a3b5268bd765681bd1c791d353 813 SMART SM00091 131 197 0.0025 T 29-03-2018 IPR000014 PAS domain SMALA_RS03090 46db70a3b5268bd765681bd1c791d353 813 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 490 683 3.3E-52 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS03090 46db70a3b5268bd765681bd1c791d353 813 SUPERFAMILY SSF55874 727 804 9.03E-6 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS03090 46db70a3b5268bd765681bd1c791d353 813 Gene3D G3DSA:3.30.450.20 127 254 1.7E-21 T 29-03-2018 SMALA_RS03090 46db70a3b5268bd765681bd1c791d353 813 SUPERFAMILY SSF81606 476 682 1.36E-7 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS03090 46db70a3b5268bd765681bd1c791d353 813 SMART SM00331 463 683 5.9E-34 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS03090 46db70a3b5268bd765681bd1c791d353 813 SUPERFAMILY SSF55781 287 436 2.62E-12 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS03090 46db70a3b5268bd765681bd1c791d353 813 Pfam PF01590 GAF domain 371 431 5.2E-6 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS03090 46db70a3b5268bd765681bd1c791d353 813 Pfam PF00989 PAS fold 19 120 4.7E-9 T 29-03-2018 IPR013767 PAS fold GO:0006355 SMALA_RS03090 46db70a3b5268bd765681bd1c791d353 813 SUPERFAMILY SSF55785 16 120 2.74E-13 T 29-03-2018 IPR000014 PAS domain SMALA_RS03090 46db70a3b5268bd765681bd1c791d353 813 Pfam PF13581 Histidine kinase-like ATPase domain 697 800 9.8E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS03090 46db70a3b5268bd765681bd1c791d353 813 Gene3D G3DSA:3.30.565.10 688 813 9.3E-12 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS33880 976691f55dfed32990d24cee91e5d061 365 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 281 297 4.9E-10 T 29-03-2018 SMALA_RS33880 976691f55dfed32990d24cee91e5d061 365 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 4.9E-10 T 29-03-2018 SMALA_RS33880 976691f55dfed32990d24cee91e5d061 365 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 172 190 4.9E-10 T 29-03-2018 SMALA_RS33880 976691f55dfed32990d24cee91e5d061 365 Gene3D G3DSA:3.50.50.60 187 360 5.5E-16 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS33880 976691f55dfed32990d24cee91e5d061 365 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 8 207 6.0E-24 T 29-03-2018 SMALA_RS33880 976691f55dfed32990d24cee91e5d061 365 SUPERFAMILY SSF51905 1 209 1.64E-41 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS33880 976691f55dfed32990d24cee91e5d061 365 Gene3D G3DSA:3.50.50.60 1 186 2.4E-35 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS33880 976691f55dfed32990d24cee91e5d061 365 SUPERFAMILY SSF51905 169 206 6.04E-11 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS33880 976691f55dfed32990d24cee91e5d061 365 SUPERFAMILY SSF51905 237 352 6.04E-11 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS33880 976691f55dfed32990d24cee91e5d061 365 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 6 28 7.1E-12 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMALA_RS33880 976691f55dfed32990d24cee91e5d061 365 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 168 192 7.1E-12 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMALA_RS10970 dc7928944927150ae528b65772bb16f9 202 SUPERFAMILY SSF48498 86 200 4.17E-23 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS10970 dc7928944927150ae528b65772bb16f9 202 ProSitePatterns PS01081 TetR-type HTH domain signature. 37 68 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site SMALA_RS10970 dc7928944927150ae528b65772bb16f9 202 SUPERFAMILY SSF46689 14 75 1.44E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS10970 dc7928944927150ae528b65772bb16f9 202 Gene3D G3DSA:1.10.357.10 70 202 1.2E-24 T 29-03-2018 SMALA_RS10970 dc7928944927150ae528b65772bb16f9 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 70 3.4E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS10970 dc7928944927150ae528b65772bb16f9 202 Pfam PF16859 Bacterial transcriptional repressor C-terminal 86 194 4.8E-24 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS10970 dc7928944927150ae528b65772bb16f9 202 Gene3D G3DSA:1.10.10.60 1 69 1.5E-17 T 29-03-2018 SMALA_RS20340 5ef37c25776f4c6c8978f4cb57e1e76c 284 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 281 9.9E-21 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS20340 5ef37c25776f4c6c8978f4cb57e1e76c 284 SUPERFAMILY SSF161098 31 275 4.19E-54 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS20340 5ef37c25776f4c6c8978f4cb57e1e76c 284 Gene3D G3DSA:1.10.3720.10 31 282 6.6E-41 T 29-03-2018 SMALA_RS20340 5ef37c25776f4c6c8978f4cb57e1e76c 284 TIGRFAM TIGR01581 Mo_ABC_porter: NifC-like ABC-type porter 52 271 1.0E-74 T 29-03-2018 IPR006469 NifC-like ABC-type porter GO:0005215|GO:0006810|GO:0016020 SMALA_RS20340 5ef37c25776f4c6c8978f4cb57e1e76c 284 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 74 277 3.1E-73 T 29-03-2018 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 SMALA_RS31725 e7f81fd90ea5da5850835a4828df8b50 693 Gene3D G3DSA:3.40.1110.10 317 453 1.2E-19 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 SMALA_RS31725 e7f81fd90ea5da5850835a4828df8b50 693 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 308 314 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 SMALA_RS31725 e7f81fd90ea5da5850835a4828df8b50 693 TIGRFAM TIGR01497 kdpB: K+-transporting ATPase, B subunit 14 686 0.0 T 29-03-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 SMALA_RS31725 e7f81fd90ea5da5850835a4828df8b50 693 Pfam PF00122 E1-E2 ATPase 118 284 5.3E-35 T 29-03-2018 SMALA_RS31725 e7f81fd90ea5da5850835a4828df8b50 693 Gene3D G3DSA:3.40.50.1000 454 582 1.1E-34 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS31725 e7f81fd90ea5da5850835a4828df8b50 693 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 374 612 1.4E-42 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMALA_RS31725 e7f81fd90ea5da5850835a4828df8b50 693 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 69 344 8.5E-30 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMALA_RS31725 e7f81fd90ea5da5850835a4828df8b50 693 SUPERFAMILY SSF56784 445 569 3.0E-38 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS31725 e7f81fd90ea5da5850835a4828df8b50 693 SUPERFAMILY SSF56784 359 406 3.0E-38 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS31725 e7f81fd90ea5da5850835a4828df8b50 693 SUPERFAMILY SSF56784 294 318 3.0E-38 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS31725 e7f81fd90ea5da5850835a4828df8b50 693 SUPERFAMILY SSF81653 117 208 5.62E-21 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 SMALA_RS31725 e7f81fd90ea5da5850835a4828df8b50 693 Hamap MF_00285 Potassium-transporting ATPase ATP-binding subunit [kdpB]. 12 690 40.423 T 29-03-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 SMALA_RS31725 e7f81fd90ea5da5850835a4828df8b50 693 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 306 320 4.9E-25 T 29-03-2018 SMALA_RS31725 e7f81fd90ea5da5850835a4828df8b50 693 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 473 483 4.9E-25 T 29-03-2018 SMALA_RS31725 e7f81fd90ea5da5850835a4828df8b50 693 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 526 545 4.9E-25 T 29-03-2018 SMALA_RS31725 e7f81fd90ea5da5850835a4828df8b50 693 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 549 561 4.9E-25 T 29-03-2018 SMALA_RS31725 e7f81fd90ea5da5850835a4828df8b50 693 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 155 169 4.9E-25 T 29-03-2018 SMALA_RS31725 e7f81fd90ea5da5850835a4828df8b50 693 Gene3D G3DSA:2.70.150.10 49 210 1.6E-25 T 29-03-2018 SMALA_RS31725 e7f81fd90ea5da5850835a4828df8b50 693 Pfam PF00702 haloacid dehalogenase-like hydrolase 302 540 5.4E-32 T 29-03-2018 SMALA_RS31725 e7f81fd90ea5da5850835a4828df8b50 693 SUPERFAMILY SSF81665 209 300 1.83E-12 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SMALA_RS31725 e7f81fd90ea5da5850835a4828df8b50 693 SUPERFAMILY SSF81665 35 100 1.83E-12 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SMALA_RS35790 a69a7aab47923344e5755400a77872ed 446 Pfam PF07690 Major Facilitator Superfamily 50 372 5.1E-26 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS35790 a69a7aab47923344e5755400a77872ed 446 Gene3D G3DSA:1.20.1250.20 222 442 4.4E-27 T 29-03-2018 SMALA_RS35790 a69a7aab47923344e5755400a77872ed 446 ProSitePatterns PS00217 Sugar transport proteins signature 2. 126 151 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMALA_RS35790 a69a7aab47923344e5755400a77872ed 446 ProSitePatterns PS00216 Sugar transport proteins signature 1. 295 312 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMALA_RS35790 a69a7aab47923344e5755400a77872ed 446 Gene3D G3DSA:1.20.1250.20 7 221 2.4E-26 T 29-03-2018 SMALA_RS35790 a69a7aab47923344e5755400a77872ed 446 SUPERFAMILY SSF103473 10 424 7.06E-67 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS06220 4fe846452881fd3d94cb5f9b68a31af8 272 Gene3D G3DSA:1.10.10.10 2 78 2.7E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS06220 4fe846452881fd3d94cb5f9b68a31af8 272 Pfam PF01614 Bacterial transcriptional regulator 135 250 4.5E-7 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal SMALA_RS06220 4fe846452881fd3d94cb5f9b68a31af8 272 Gene3D G3DSA:3.30.450.40 88 259 2.1E-27 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS06220 4fe846452881fd3d94cb5f9b68a31af8 272 SMART SM00346 21 107 1.1E-16 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMALA_RS06220 4fe846452881fd3d94cb5f9b68a31af8 272 SUPERFAMILY SSF46785 21 88 1.36E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS06220 4fe846452881fd3d94cb5f9b68a31af8 272 SUPERFAMILY SSF55781 77 253 1.8E-24 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS06220 4fe846452881fd3d94cb5f9b68a31af8 272 Pfam PF09339 IclR helix-turn-helix domain 21 69 4.7E-13 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMALA_RS35195 820ccffe43584af377653f2545786c43 570 Pfam PF07730 Histidine kinase 374 436 2.4E-9 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMALA_RS35195 820ccffe43584af377653f2545786c43 570 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 485 566 6.5E-6 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS35195 820ccffe43584af377653f2545786c43 570 SUPERFAMILY SSF55781 33 216 3.93E-39 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS35195 820ccffe43584af377653f2545786c43 570 SUPERFAMILY SSF55874 479 567 6.68E-14 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS35195 820ccffe43584af377653f2545786c43 570 Gene3D G3DSA:3.30.450.40 203 366 1.7E-28 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS35195 820ccffe43584af377653f2545786c43 570 Gene3D G3DSA:3.30.450.40 13 202 2.0E-33 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS35195 820ccffe43584af377653f2545786c43 570 Gene3D G3DSA:3.30.565.10 367 568 6.6E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS35195 820ccffe43584af377653f2545786c43 570 SMART SM00065 219 366 2.6E-8 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS35195 820ccffe43584af377653f2545786c43 570 SMART SM00065 51 198 1.3E-18 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS35195 820ccffe43584af377653f2545786c43 570 SUPERFAMILY SSF55781 200 383 4.36E-25 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS35195 820ccffe43584af377653f2545786c43 570 Pfam PF13185 GAF domain 50 189 5.3E-19 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS35195 820ccffe43584af377653f2545786c43 570 Pfam PF13185 GAF domain 219 356 1.2E-15 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS35195 820ccffe43584af377653f2545786c43 570 SMART SM00387 479 569 2.5E-9 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS04150 ab1fa22ab6df66ebc849676dea923e99 180 Pfam PF13384 Homeodomain-like domain 17 63 1.7E-6 T 29-03-2018 SMALA_RS04150 ab1fa22ab6df66ebc849676dea923e99 180 Pfam PF13592 Winged helix-turn helix 98 155 2.5E-23 T 29-03-2018 IPR025959 Winged helix-turn helix domain SMALA_RS04150 ab1fa22ab6df66ebc849676dea923e99 180 SUPERFAMILY SSF46689 1 131 1.97E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS04150 ab1fa22ab6df66ebc849676dea923e99 180 Gene3D G3DSA:1.10.10.60 18 156 3.3E-6 T 29-03-2018 SMALA_RS40505 41bc5dd7158dc23e84c04e989d931b57 247 SMART SM00382 39 218 7.6E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS40505 41bc5dd7158dc23e84c04e989d931b57 247 SUPERFAMILY SSF52540 10 225 2.1E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS40505 41bc5dd7158dc23e84c04e989d931b57 247 Gene3D G3DSA:3.40.50.300 6 244 1.0E-53 T 29-03-2018 SMALA_RS40505 41bc5dd7158dc23e84c04e989d931b57 247 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS40505 41bc5dd7158dc23e84c04e989d931b57 247 Pfam PF00005 ABC transporter 33 169 2.6E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS39355 8e3fc7b0e132a5acb3642d4e871edf7e 337 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 32 98 5.5E-8 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS39355 8e3fc7b0e132a5acb3642d4e871edf7e 337 SMART SM00829 15 334 9.7E-15 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS39355 8e3fc7b0e132a5acb3642d4e871edf7e 337 Gene3D G3DSA:3.40.50.720 148 258 2.4E-22 T 29-03-2018 SMALA_RS39355 8e3fc7b0e132a5acb3642d4e871edf7e 337 SUPERFAMILY SSF51735 129 262 3.77E-31 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS39355 8e3fc7b0e132a5acb3642d4e871edf7e 337 Gene3D G3DSA:3.90.180.10 3 147 3.1E-45 T 29-03-2018 SMALA_RS39355 8e3fc7b0e132a5acb3642d4e871edf7e 337 Pfam PF13602 Zinc-binding dehydrogenase 214 334 8.2E-25 T 29-03-2018 SMALA_RS39355 8e3fc7b0e132a5acb3642d4e871edf7e 337 SUPERFAMILY SSF50129 6 154 2.89E-38 T 29-03-2018 IPR011032 GroES-like SMALA_RS39355 8e3fc7b0e132a5acb3642d4e871edf7e 337 Gene3D G3DSA:3.90.180.10 259 337 1.6E-8 T 29-03-2018 SMALA_RS13945 06939c0513daa65a5004d9eec8d3cde1 338 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 2.6E-6 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS13945 06939c0513daa65a5004d9eec8d3cde1 338 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 2.6E-6 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS13945 06939c0513daa65a5004d9eec8d3cde1 338 SMART SM00354 1 71 1.8E-36 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS13945 06939c0513daa65a5004d9eec8d3cde1 338 SUPERFAMILY SSF53822 60 333 1.68E-74 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SMALA_RS13945 06939c0513daa65a5004d9eec8d3cde1 338 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 29-03-2018 SMALA_RS13945 06939c0513daa65a5004d9eec8d3cde1 338 Gene3D G3DSA:3.40.50.2300 55 177 2.3E-40 T 29-03-2018 SMALA_RS13945 06939c0513daa65a5004d9eec8d3cde1 338 Pfam PF13377 Periplasmic binding protein-like domain 171 330 7.7E-34 T 29-03-2018 SMALA_RS13945 06939c0513daa65a5004d9eec8d3cde1 338 SUPERFAMILY SSF47413 2 59 3.12E-20 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS13945 06939c0513daa65a5004d9eec8d3cde1 338 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 48 4.6E-21 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS13945 06939c0513daa65a5004d9eec8d3cde1 338 Gene3D G3DSA:3.40.50.2300 178 315 1.7E-42 T 29-03-2018 SMALA_RS13945 06939c0513daa65a5004d9eec8d3cde1 338 Gene3D G3DSA:1.10.260.40 3 54 1.7E-26 T 29-03-2018 SMALA_RS06010 55298e01117a498d228f92d74f507b18 225 SMART SM00862 145 220 7.8E-25 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS06010 55298e01117a498d228f92d74f507b18 225 Gene3D G3DSA:1.10.10.10 119 224 1.5E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS06010 55298e01117a498d228f92d74f507b18 225 SMART SM00448 1 112 5.3E-40 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS06010 55298e01117a498d228f92d74f507b18 225 SUPERFAMILY SSF52172 1 174 9.08E-41 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS06010 55298e01117a498d228f92d74f507b18 225 Pfam PF00072 Response regulator receiver domain 3 112 4.9E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS06010 55298e01117a498d228f92d74f507b18 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 220 2.1E-24 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS06010 55298e01117a498d228f92d74f507b18 225 Gene3D G3DSA:3.40.50.2300 1 118 9.0E-37 T 29-03-2018 SMALA_RS23085 7541efd048518b994666206652a0aa37 384 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 11 33 1.2E-9 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMALA_RS23085 7541efd048518b994666206652a0aa37 384 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 130 138 1.2E-9 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMALA_RS23085 7541efd048518b994666206652a0aa37 384 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 169 193 1.2E-9 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMALA_RS23085 7541efd048518b994666206652a0aa37 384 PIRSF PIRSF000332 8 334 5.0E-27 T 29-03-2018 SMALA_RS23085 7541efd048518b994666206652a0aa37 384 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 14 204 1.9E-26 T 29-03-2018 SMALA_RS23085 7541efd048518b994666206652a0aa37 384 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 12 31 4.8E-7 T 29-03-2018 SMALA_RS23085 7541efd048518b994666206652a0aa37 384 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 173 191 4.8E-7 T 29-03-2018 SMALA_RS23085 7541efd048518b994666206652a0aa37 384 SUPERFAMILY SSF51905 265 380 9.19E-7 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS23085 7541efd048518b994666206652a0aa37 384 SUPERFAMILY SSF51905 166 208 9.19E-7 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS23085 7541efd048518b994666206652a0aa37 384 SUPERFAMILY SSF51905 12 234 1.73E-41 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS23085 7541efd048518b994666206652a0aa37 384 Gene3D G3DSA:3.40.50.720 174 347 1.9E-13 T 29-03-2018 SMALA_RS23085 7541efd048518b994666206652a0aa37 384 Gene3D G3DSA:3.50.50.60 7 173 1.6E-35 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS00175 f303e718e29601817a59c6ba87b3dabe 293 PIRSF PIRSF006221 34 293 2.0E-56 T 29-03-2018 IPR016477 Fructosamine/Ketosamine-3-kinase Reactome: R-HSA-163841 SMALA_RS00175 f303e718e29601817a59c6ba87b3dabe 293 Gene3D G3DSA:3.30.200.20 19 89 3.6E-13 T 29-03-2018 SMALA_RS00175 f303e718e29601817a59c6ba87b3dabe 293 Gene3D G3DSA:3.90.1200.10 94 279 1.2E-21 T 29-03-2018 SMALA_RS00175 f303e718e29601817a59c6ba87b3dabe 293 Pfam PF03881 Fructosamine kinase 57 290 8.2E-44 T 29-03-2018 IPR016477 Fructosamine/Ketosamine-3-kinase Reactome: R-HSA-163841 SMALA_RS00175 f303e718e29601817a59c6ba87b3dabe 293 SUPERFAMILY SSF56112 32 283 3.79E-39 T 29-03-2018 IPR011009 Protein kinase-like domain SMALA_RS05015 00fc30e57e8f023bb1315abc6158047a 357 Gene3D G3DSA:3.20.20.30 2 356 8.2E-74 T 29-03-2018 SMALA_RS05015 00fc30e57e8f023bb1315abc6158047a 357 SUPERFAMILY SSF51679 4 354 1.3E-72 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS05015 00fc30e57e8f023bb1315abc6158047a 357 Pfam PF00296 Luciferase-like monooxygenase 5 329 1.5E-68 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS32310 5c4e4a1e6769f64fca785869368d68a4 127 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 21 72 2.0E-23 T 29-03-2018 SMALA_RS32310 5c4e4a1e6769f64fca785869368d68a4 127 SUPERFAMILY SSF74731 3 117 1.7E-45 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS32310 5c4e4a1e6769f64fca785869368d68a4 127 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 2 113 6.3E-45 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS32310 5c4e4a1e6769f64fca785869368d68a4 127 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS32310 5c4e4a1e6769f64fca785869368d68a4 127 PRINTS PR00062 Ribosomal protein L20 signature 12 41 3.4E-38 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS32310 5c4e4a1e6769f64fca785869368d68a4 127 PRINTS PR00062 Ribosomal protein L20 signature 42 71 3.4E-38 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS32310 5c4e4a1e6769f64fca785869368d68a4 127 PRINTS PR00062 Ribosomal protein L20 signature 75 101 3.4E-38 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS32310 5c4e4a1e6769f64fca785869368d68a4 127 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 27.859 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS32310 5c4e4a1e6769f64fca785869368d68a4 127 Gene3D G3DSA:1.10.1900.20 56 116 4.8E-28 T 29-03-2018 IPR035566 Ribosomal protein L20 C-terminal domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS32310 5c4e4a1e6769f64fca785869368d68a4 127 Pfam PF00453 Ribosomal protein L20 3 109 1.0E-44 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS08995 0a0fc154b75f27d265b4da4ba89a7295 512 SUPERFAMILY SSF111283 12 503 8.37E-94 T 29-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 SMALA_RS08995 0a0fc154b75f27d265b4da4ba89a7295 512 Gene3D G3DSA:3.30.2290.10 1 243 1.7E-54 T 29-03-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal domain SMALA_RS08995 0a0fc154b75f27d265b4da4ba89a7295 512 Pfam PF01523 Putative modulator of DNA gyrase 32 352 2.1E-53 T 29-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 SMALA_RS15370 aa0b9b3edb8ca8bfb841b63cc4203201 473 Pfam PF00390 Malic enzyme, N-terminal domain 94 226 3.2E-31 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 SMALA_RS15370 aa0b9b3edb8ca8bfb841b63cc4203201 473 SMART SM01274 93 226 2.9E-85 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 SMALA_RS15370 aa0b9b3edb8ca8bfb841b63cc4203201 473 SUPERFAMILY SSF51735 238 465 1.09E-65 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS15370 aa0b9b3edb8ca8bfb841b63cc4203201 473 PIRSF PIRSF000106 70 472 3.5E-81 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 SMALA_RS15370 aa0b9b3edb8ca8bfb841b63cc4203201 473 Gene3D G3DSA:3.40.50.10380 89 235 9.1E-40 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 SMALA_RS15370 aa0b9b3edb8ca8bfb841b63cc4203201 473 Gene3D G3DSA:3.40.50.720 236 472 2.7E-67 T 29-03-2018 SMALA_RS15370 aa0b9b3edb8ca8bfb841b63cc4203201 473 SMART SM00919 238 465 2.1E-110 T 29-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 SMALA_RS15370 aa0b9b3edb8ca8bfb841b63cc4203201 473 SUPERFAMILY SSF53223 87 236 3.53E-57 T 29-03-2018 SMALA_RS15370 aa0b9b3edb8ca8bfb841b63cc4203201 473 Gene3D G3DSA:3.30.70.260 11 88 1.5E-4 T 29-03-2018 SMALA_RS15370 aa0b9b3edb8ca8bfb841b63cc4203201 473 PRINTS PR00072 Malic enzyme signature 155 177 1.4E-11 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 SMALA_RS15370 aa0b9b3edb8ca8bfb841b63cc4203201 473 PRINTS PR00072 Malic enzyme signature 234 250 1.4E-11 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 SMALA_RS15370 aa0b9b3edb8ca8bfb841b63cc4203201 473 PRINTS PR00072 Malic enzyme signature 358 374 1.4E-11 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 SMALA_RS15370 aa0b9b3edb8ca8bfb841b63cc4203201 473 PRINTS PR00072 Malic enzyme signature 265 281 1.4E-11 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 SMALA_RS15370 aa0b9b3edb8ca8bfb841b63cc4203201 473 Pfam PF03949 Malic enzyme, NAD binding domain 240 462 4.4E-22 T 29-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 SMALA_RS36965 4531e98f92a5bd2f8ac619eff45483c8 1168 Gene3D G3DSA:2.60.120.430 609 782 7.3E-29 T 29-03-2018 SMALA_RS36965 4531e98f92a5bd2f8ac619eff45483c8 1168 SUPERFAMILY SSF56300 797 1018 1.58E-24 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SMALA_RS36965 4531e98f92a5bd2f8ac619eff45483c8 1168 Pfam PF00149 Calcineurin-like phosphoesterase 799 991 5.3E-11 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 SMALA_RS36965 4531e98f92a5bd2f8ac619eff45483c8 1168 Gene3D G3DSA:2.60.40.1080 447 528 2.5E-5 T 29-03-2018 SMALA_RS36965 4531e98f92a5bd2f8ac619eff45483c8 1168 Gene3D G3DSA:2.60.40.1080 1059 1161 1.0E-9 T 29-03-2018 SMALA_RS36965 4531e98f92a5bd2f8ac619eff45483c8 1168 Gene3D G3DSA:3.60.21.10 788 1058 1.1E-27 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SMALA_RS36965 4531e98f92a5bd2f8ac619eff45483c8 1168 Pfam PF09992 Phosphodiester glycosidase 248 422 6.0E-29 T 29-03-2018 IPR018711 Phosphodiester glycosidase SMALA_RS27345 3b9d420d3404174b70d8fde091f4a262 886 Pfam PF00343 Carbohydrate phosphorylase 155 200 5.8E-6 T 29-03-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 SMALA_RS27345 3b9d420d3404174b70d8fde091f4a262 886 Pfam PF00343 Carbohydrate phosphorylase 304 639 1.3E-15 T 29-03-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 SMALA_RS27345 3b9d420d3404174b70d8fde091f4a262 886 SUPERFAMILY SSF53756 4 104 4.49E-190 T 29-03-2018 SMALA_RS27345 3b9d420d3404174b70d8fde091f4a262 886 SUPERFAMILY SSF53756 137 757 4.49E-190 T 29-03-2018 SMALA_RS27345 3b9d420d3404174b70d8fde091f4a262 886 TIGRFAM TIGR02094 more_P_ylases: alpha-glucan phosphorylases 137 729 1.2E-226 T 29-03-2018 IPR011834 Alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 SMALA_RS27345 3b9d420d3404174b70d8fde091f4a262 886 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 617 629 - T 29-03-2018 IPR035090 Phosphorylase pyridoxal-phosphate attachment site KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 SMALA_RS27345 3b9d420d3404174b70d8fde091f4a262 886 Gene3D G3DSA:3.40.50.2000 461 752 2.1E-77 T 29-03-2018 SMALA_RS27345 3b9d420d3404174b70d8fde091f4a262 886 PIRSF PIRSF000460 124 816 1.9E-231 T 29-03-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 SMALA_RS27345 3b9d420d3404174b70d8fde091f4a262 886 PIRSF PIRSF000460 1 110 1.5E-11 T 29-03-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 SMALA_RS27345 3b9d420d3404174b70d8fde091f4a262 886 Gene3D G3DSA:3.40.50.2000 143 279 3.7E-33 T 29-03-2018 SMALA_RS27345 3b9d420d3404174b70d8fde091f4a262 886 Gene3D G3DSA:3.40.50.2000 280 460 1.8E-53 T 29-03-2018 SMALA_RS27345 3b9d420d3404174b70d8fde091f4a262 886 Pfam PF11897 Protein of unknown function (DUF3417) 13 150 1.9E-30 T 29-03-2018 IPR024517 Glycogen phosphorylase, domain of unknown function DUF3417 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 SMALA_RS39805 72f3243be320021fcf6e06a5a79109b9 512 Gene3D G3DSA:3.40.50.300 12 266 3.6E-48 T 29-03-2018 SMALA_RS39805 72f3243be320021fcf6e06a5a79109b9 512 Gene3D G3DSA:3.40.50.300 271 499 1.3E-33 T 29-03-2018 SMALA_RS39805 72f3243be320021fcf6e06a5a79109b9 512 SUPERFAMILY SSF52540 14 236 4.36E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS39805 72f3243be320021fcf6e06a5a79109b9 512 Pfam PF00005 ABC transporter 285 432 1.4E-14 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS39805 72f3243be320021fcf6e06a5a79109b9 512 Pfam PF00005 ABC transporter 33 180 5.2E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS39805 72f3243be320021fcf6e06a5a79109b9 512 ProSitePatterns PS00211 ABC transporters family signature. 404 418 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS39805 72f3243be320021fcf6e06a5a79109b9 512 SMART SM00382 40 228 1.9E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS39805 72f3243be320021fcf6e06a5a79109b9 512 SMART SM00382 289 481 1.9E-6 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS39805 72f3243be320021fcf6e06a5a79109b9 512 SUPERFAMILY SSF52540 283 490 1.16E-38 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS08890 5dff5656bf2781d476407d2cd36ead12 883 ProSitePatterns PS00211 ABC transporters family signature. 452 466 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS08890 5dff5656bf2781d476407d2cd36ead12 883 SMART SM00240 24 74 8.2E-10 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 SMALA_RS08890 5dff5656bf2781d476407d2cd36ead12 883 SMART SM00240 230 281 2.0E-15 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 SMALA_RS08890 5dff5656bf2781d476407d2cd36ead12 883 SUPERFAMILY SSF49879 13 90 3.44E-22 T 29-03-2018 IPR008984 SMAD/FHA domain GO:0005515 SMALA_RS08890 5dff5656bf2781d476407d2cd36ead12 883 Pfam PF01061 ABC-2 type transporter 605 814 9.8E-19 T 29-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 SMALA_RS08890 5dff5656bf2781d476407d2cd36ead12 883 Gene3D G3DSA:2.60.200.20 7 93 7.7E-22 T 29-03-2018 SMALA_RS08890 5dff5656bf2781d476407d2cd36ead12 883 SMART SM00382 342 536 1.4E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS08890 5dff5656bf2781d476407d2cd36ead12 883 Pfam PF00005 ABC transporter 333 480 1.4E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS08890 5dff5656bf2781d476407d2cd36ead12 883 SUPERFAMILY SSF52540 311 548 4.61E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS08890 5dff5656bf2781d476407d2cd36ead12 883 SUPERFAMILY SSF49879 172 323 4.97E-28 T 29-03-2018 IPR008984 SMAD/FHA domain GO:0005515 SMALA_RS08890 5dff5656bf2781d476407d2cd36ead12 883 Gene3D G3DSA:2.60.200.20 145 312 1.8E-27 T 29-03-2018 SMALA_RS08890 5dff5656bf2781d476407d2cd36ead12 883 Gene3D G3DSA:3.40.50.300 314 602 4.6E-67 T 29-03-2018 SMALA_RS08890 5dff5656bf2781d476407d2cd36ead12 883 Pfam PF00498 FHA domain 25 88 8.7E-16 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 SMALA_RS08890 5dff5656bf2781d476407d2cd36ead12 883 Pfam PF00498 FHA domain 232 292 4.4E-16 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 SMALA_RS38725 9b169325d2d8f591752074920bc340c3 269 Pfam PF01471 Putative peptidoglycan binding domain 214 267 5.9E-17 T 29-03-2018 IPR002477 Peptidoglycan binding-like SMALA_RS38725 9b169325d2d8f591752074920bc340c3 269 Gene3D G3DSA:1.10.260.40 10 92 1.7E-8 T 29-03-2018 SMALA_RS38725 9b169325d2d8f591752074920bc340c3 269 SMART SM00530 21 76 1.9E-5 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS38725 9b169325d2d8f591752074920bc340c3 269 Gene3D G3DSA:1.10.101.10 197 269 1.4E-20 T 29-03-2018 IPR002477 Peptidoglycan binding-like SMALA_RS38725 9b169325d2d8f591752074920bc340c3 269 SUPERFAMILY SSF47413 17 79 4.38E-6 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS38725 9b169325d2d8f591752074920bc340c3 269 SUPERFAMILY SSF47090 205 268 2.22E-18 T 29-03-2018 IPR002477 Peptidoglycan binding-like SMALA_RS38725 9b169325d2d8f591752074920bc340c3 269 Pfam PF13560 Helix-turn-helix domain 18 74 4.2E-9 T 29-03-2018 SMALA_RS12035 8eb908fe39872a738c19ea0466c8ab5e 82 SUPERFAMILY SSF47336 2 81 6.02E-22 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS12035 8eb908fe39872a738c19ea0466c8ab5e 82 Hamap MF_01217 Acyl carrier protein [acpP]. 7 81 17.921 T 29-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 SMALA_RS12035 8eb908fe39872a738c19ea0466c8ab5e 82 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 38 80 1.0E-16 T 29-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 SMALA_RS12035 8eb908fe39872a738c19ea0466c8ab5e 82 Gene3D G3DSA:1.10.1200.10 2 82 3.0E-23 T 29-03-2018 SMALA_RS12035 8eb908fe39872a738c19ea0466c8ab5e 82 Pfam PF00550 Phosphopantetheine attachment site 12 77 5.8E-16 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS12035 8eb908fe39872a738c19ea0466c8ab5e 82 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 6 81 6.6E-21 T 29-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 SMALA_RS20385 ca26dd9971a6acf0a9ca3253103057b3 327 SUPERFAMILY SSF46689 220 269 1.33E-9 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS20385 ca26dd9971a6acf0a9ca3253103057b3 327 Pfam PF01965 DJ-1/PfpI family 8 178 3.5E-18 T 29-03-2018 IPR002818 DJ-1/PfpI SMALA_RS20385 ca26dd9971a6acf0a9ca3253103057b3 327 Gene3D G3DSA:3.40.50.880 1 237 1.5E-65 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS20385 ca26dd9971a6acf0a9ca3253103057b3 327 Gene3D G3DSA:1.10.10.60 277 327 1.7E-11 T 29-03-2018 SMALA_RS20385 ca26dd9971a6acf0a9ca3253103057b3 327 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 272 314 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 SMALA_RS20385 ca26dd9971a6acf0a9ca3253103057b3 327 Pfam PF12833 Helix-turn-helix domain 241 319 2.6E-20 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS20385 ca26dd9971a6acf0a9ca3253103057b3 327 SMART SM00342 235 318 8.5E-29 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS20385 ca26dd9971a6acf0a9ca3253103057b3 327 Gene3D G3DSA:1.10.10.60 238 276 1.7E-11 T 29-03-2018 SMALA_RS20385 ca26dd9971a6acf0a9ca3253103057b3 327 SUPERFAMILY SSF52317 8 199 8.25E-48 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS20385 ca26dd9971a6acf0a9ca3253103057b3 327 SUPERFAMILY SSF46689 272 322 7.43E-10 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS18225 a279c6df81b0612338c4bf31be6e9789 345 Gene3D G3DSA:3.30.420.40 9 162 3.4E-16 T 29-03-2018 SMALA_RS18225 a279c6df81b0612338c4bf31be6e9789 345 SUPERFAMILY SSF53067 11 149 1.78E-18 T 29-03-2018 SMALA_RS18225 a279c6df81b0612338c4bf31be6e9789 345 Gene3D G3DSA:3.30.420.40 163 250 1.3E-15 T 29-03-2018 SMALA_RS18225 a279c6df81b0612338c4bf31be6e9789 345 Gene3D G3DSA:3.30.420.40 251 319 6.2E-8 T 29-03-2018 SMALA_RS18225 a279c6df81b0612338c4bf31be6e9789 345 Pfam PF06723 MreB/Mbl protein 11 332 3.0E-100 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 SMALA_RS18225 a279c6df81b0612338c4bf31be6e9789 345 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 302 328 1.0E-33 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 SMALA_RS18225 a279c6df81b0612338c4bf31be6e9789 345 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 188 208 1.0E-33 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 SMALA_RS18225 a279c6df81b0612338c4bf31be6e9789 345 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 68 91 1.0E-33 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 SMALA_RS18225 a279c6df81b0612338c4bf31be6e9789 345 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 133 152 1.0E-33 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 SMALA_RS18225 a279c6df81b0612338c4bf31be6e9789 345 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 48 66 1.0E-33 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 SMALA_RS18225 a279c6df81b0612338c4bf31be6e9789 345 SUPERFAMILY SSF53067 150 330 5.73E-30 T 29-03-2018 SMALA_RS05175 5fae8530dac9100593583d20bf250365 427 Gene3D G3DSA:1.25.40.10 178 351 1.8E-19 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS05175 5fae8530dac9100593583d20bf250365 427 Gene3D G3DSA:1.25.40.10 51 174 4.6E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS05175 5fae8530dac9100593583d20bf250365 427 SUPERFAMILY SSF48452 297 408 1.9E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS05175 5fae8530dac9100593583d20bf250365 427 SUPERFAMILY SSF48452 181 328 1.39E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS05175 5fae8530dac9100593583d20bf250365 427 SUPERFAMILY SSF48452 64 169 5.84E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS05175 5fae8530dac9100593583d20bf250365 427 Gene3D G3DSA:1.10.260.40 1 50 3.9E-7 T 29-03-2018 SMALA_RS05175 5fae8530dac9100593583d20bf250365 427 Gene3D G3DSA:1.25.40.10 352 412 4.5E-4 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS05175 5fae8530dac9100593583d20bf250365 427 SUPERFAMILY SSF47413 1 46 2.02E-5 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS36120 7a142602b20ee77ddc4d8b70f7db7989 334 SUPERFAMILY SSF47413 5 63 5.63E-18 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS36120 7a142602b20ee77ddc4d8b70f7db7989 334 SMART SM00354 5 75 1.4E-25 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS36120 7a142602b20ee77ddc4d8b70f7db7989 334 Gene3D G3DSA:1.10.260.40 21 58 9.3E-23 T 29-03-2018 SMALA_RS36120 7a142602b20ee77ddc4d8b70f7db7989 334 Pfam PF00356 Bacterial regulatory proteins, lacI family 7 52 4.0E-17 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS36120 7a142602b20ee77ddc4d8b70f7db7989 334 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 7 17 3.3E-5 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS36120 7a142602b20ee77ddc4d8b70f7db7989 334 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 17 27 3.3E-5 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS36120 7a142602b20ee77ddc4d8b70f7db7989 334 Gene3D G3DSA:1.10.10.60 1 20 4.7E-4 T 29-03-2018 SMALA_RS36120 7a142602b20ee77ddc4d8b70f7db7989 334 SUPERFAMILY SSF53822 80 333 8.52E-66 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SMALA_RS36120 7a142602b20ee77ddc4d8b70f7db7989 334 Pfam PF13377 Periplasmic binding protein-like domain 177 333 2.9E-37 T 29-03-2018 SMALA_RS36120 7a142602b20ee77ddc4d8b70f7db7989 334 Gene3D G3DSA:3.40.50.2300 184 334 4.4E-45 T 29-03-2018 SMALA_RS36120 7a142602b20ee77ddc4d8b70f7db7989 334 Gene3D G3DSA:3.40.50.2300 59 183 2.2E-33 T 29-03-2018 SMALA_RS21670 b99830a29149eff0abf0595d6ab3fc44 474 Gene3D G3DSA:3.30.230.10 288 456 1.2E-23 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SMALA_RS21670 b99830a29149eff0abf0595d6ab3fc44 474 Hamap MF_01498 DNA repair protein RadA [radA]. 30 457 42.222 T 29-03-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 SMALA_RS21670 b99830a29149eff0abf0595d6ab3fc44 474 Gene3D G3DSA:3.40.50.300 77 284 2.2E-41 T 29-03-2018 SMALA_RS21670 b99830a29149eff0abf0595d6ab3fc44 474 TIGRFAM TIGR00416 sms: DNA repair protein RadA 11 453 1.9E-153 T 29-03-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 SMALA_RS21670 b99830a29149eff0abf0595d6ab3fc44 474 SUPERFAMILY SSF54211 296 456 1.52E-33 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SMALA_RS21670 b99830a29149eff0abf0595d6ab3fc44 474 Pfam PF13541 Subunit ChlI of Mg-chelatase 372 431 1.0E-7 T 29-03-2018 SMALA_RS21670 b99830a29149eff0abf0595d6ab3fc44 474 SUPERFAMILY SSF52540 74 296 2.3E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS21670 b99830a29149eff0abf0595d6ab3fc44 474 Pfam PF13481 AAA domain 85 225 4.9E-14 T 29-03-2018 SMALA_RS21670 b99830a29149eff0abf0595d6ab3fc44 474 PRINTS PR01874 DNA repair protein radA signature 85 113 1.2E-85 T 29-03-2018 SMALA_RS21670 b99830a29149eff0abf0595d6ab3fc44 474 PRINTS PR01874 DNA repair protein radA signature 325 348 1.2E-85 T 29-03-2018 SMALA_RS21670 b99830a29149eff0abf0595d6ab3fc44 474 PRINTS PR01874 DNA repair protein radA signature 19 43 1.2E-85 T 29-03-2018 SMALA_RS21670 b99830a29149eff0abf0595d6ab3fc44 474 PRINTS PR01874 DNA repair protein radA signature 251 277 1.2E-85 T 29-03-2018 SMALA_RS21670 b99830a29149eff0abf0595d6ab3fc44 474 PRINTS PR01874 DNA repair protein radA signature 177 201 1.2E-85 T 29-03-2018 SMALA_RS21670 b99830a29149eff0abf0595d6ab3fc44 474 PRINTS PR01874 DNA repair protein radA signature 127 144 1.2E-85 T 29-03-2018 SMALA_RS21670 b99830a29149eff0abf0595d6ab3fc44 474 PRINTS PR01874 DNA repair protein radA signature 216 244 1.2E-85 T 29-03-2018 SMALA_RS21670 b99830a29149eff0abf0595d6ab3fc44 474 SMART SM00382 93 247 2.7E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS01275 96a7566d40d543241d6ae856e567d91c 202 Pfam PF13581 Histidine kinase-like ATPase domain 81 181 1.9E-11 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS01275 96a7566d40d543241d6ae856e567d91c 202 Gene3D G3DSA:3.30.565.10 73 199 3.0E-14 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS01275 96a7566d40d543241d6ae856e567d91c 202 SUPERFAMILY SSF55874 103 196 1.62E-7 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS32930 47cbffe229da27dca80aeb12a48cb06f 596 Pfam PF07549 SecD/SecF GG Motif 39 61 2.9E-4 T 29-03-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site SMALA_RS32930 47cbffe229da27dca80aeb12a48cb06f 596 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 45 551 5.1E-107 T 29-03-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 SMALA_RS32930 47cbffe229da27dca80aeb12a48cb06f 596 Gene3D G3DSA:1.20.1640.10 339 558 9.9E-29 T 29-03-2018 SMALA_RS32930 47cbffe229da27dca80aeb12a48cb06f 596 SUPERFAMILY SSF82866 357 557 1.7E-37 T 29-03-2018 SMALA_RS32930 47cbffe229da27dca80aeb12a48cb06f 596 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 306 543 2.0E-62 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial SMALA_RS32930 47cbffe229da27dca80aeb12a48cb06f 596 Pfam PF02355 Protein export membrane protein 380 555 3.0E-11 T 29-03-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial SMALA_RS32930 47cbffe229da27dca80aeb12a48cb06f 596 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 9 565 38.848 T 29-03-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 SMALA_RS33395 c23e33ec8ab60f5fcaf708cba705f898 465 Gene3D G3DSA:3.40.1060.10 154 287 1.1E-43 T 29-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS33395 c23e33ec8ab60f5fcaf708cba705f898 465 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 4 459 1.1E-207 T 29-03-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 SMALA_RS33395 c23e33ec8ab60f5fcaf708cba705f898 465 Gene3D G3DSA:3.30.499.10 1 153 1.9E-37 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS33395 c23e33ec8ab60f5fcaf708cba705f898 465 PRINTS PR00415 Aconitase family signature 107 115 7.0E-45 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS33395 c23e33ec8ab60f5fcaf708cba705f898 465 PRINTS PR00415 Aconitase family signature 194 207 7.0E-45 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS33395 c23e33ec8ab60f5fcaf708cba705f898 465 PRINTS PR00415 Aconitase family signature 132 147 7.0E-45 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS33395 c23e33ec8ab60f5fcaf708cba705f898 465 PRINTS PR00415 Aconitase family signature 81 94 7.0E-45 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS33395 c23e33ec8ab60f5fcaf708cba705f898 465 PRINTS PR00415 Aconitase family signature 118 131 7.0E-45 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS33395 c23e33ec8ab60f5fcaf708cba705f898 465 PRINTS PR00415 Aconitase family signature 398 411 7.0E-45 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS33395 c23e33ec8ab60f5fcaf708cba705f898 465 PRINTS PR00415 Aconitase family signature 208 221 7.0E-45 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS33395 c23e33ec8ab60f5fcaf708cba705f898 465 PRINTS PR00415 Aconitase family signature 285 299 7.0E-45 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS33395 c23e33ec8ab60f5fcaf708cba705f898 465 PRINTS PR00415 Aconitase family signature 342 353 7.0E-45 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS33395 c23e33ec8ab60f5fcaf708cba705f898 465 Gene3D G3DSA:3.30.499.10 324 465 3.3E-50 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS33395 c23e33ec8ab60f5fcaf708cba705f898 465 ProSitePatterns PS00450 Aconitase family signature 1. 338 354 - T 29-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 SMALA_RS33395 c23e33ec8ab60f5fcaf708cba705f898 465 Pfam PF00330 Aconitase family (aconitate hydratase) 9 456 9.0E-150 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS33395 c23e33ec8ab60f5fcaf708cba705f898 465 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 3 465 55.529 T 29-03-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 SMALA_RS33395 c23e33ec8ab60f5fcaf708cba705f898 465 SUPERFAMILY SSF53732 3 464 1.83E-160 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS33395 c23e33ec8ab60f5fcaf708cba705f898 465 ProSitePatterns PS01244 Aconitase family signature 2. 398 411 - T 29-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 SMALA_RS11425 d29a6b15b1266d305fe0d2d17f058b61 445 Gene3D G3DSA:3.40.50.2000 21 255 2.6E-18 T 29-03-2018 SMALA_RS11425 d29a6b15b1266d305fe0d2d17f058b61 445 Pfam PF00534 Glycosyl transferases group 1 259 414 4.6E-29 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 SMALA_RS11425 d29a6b15b1266d305fe0d2d17f058b61 445 SUPERFAMILY SSF53756 29 436 5.32E-83 T 29-03-2018 SMALA_RS11425 d29a6b15b1266d305fe0d2d17f058b61 445 Pfam PF13439 Glycosyltransferase Family 4 41 244 9.6E-28 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 SMALA_RS11425 d29a6b15b1266d305fe0d2d17f058b61 445 Gene3D G3DSA:3.40.50.2000 257 427 2.0E-40 T 29-03-2018 SMALA_RS14360 3267165ab35b1e2cd90580c93d922e0c 201 SUPERFAMILY SSF46689 6 79 1.95E-18 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS14360 3267165ab35b1e2cd90580c93d922e0c 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 64 7.8E-16 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS14360 3267165ab35b1e2cd90580c93d922e0c 201 Gene3D G3DSA:1.10.10.60 1 60 1.6E-20 T 29-03-2018 SMALA_RS14360 3267165ab35b1e2cd90580c93d922e0c 201 Gene3D G3DSA:1.10.357.10 61 188 1.8E-19 T 29-03-2018 SMALA_RS14360 3267165ab35b1e2cd90580c93d922e0c 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 1.0E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS14360 3267165ab35b1e2cd90580c93d922e0c 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 1.0E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS30665 298322b03cd2d5ec314b2af77d82c8a2 259 SUPERFAMILY SSF56219 1 258 1.44E-68 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMALA_RS30665 298322b03cd2d5ec314b2af77d82c8a2 259 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 257 7.7E-78 T 29-03-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 SMALA_RS30665 298322b03cd2d5ec314b2af77d82c8a2 259 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 4 250 5.0E-19 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMALA_RS30665 298322b03cd2d5ec314b2af77d82c8a2 259 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 1 256 2.3E-58 T 29-03-2018 SMALA_RS30665 298322b03cd2d5ec314b2af77d82c8a2 259 Gene3D G3DSA:3.60.10.10 1 259 5.0E-43 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMALA_RS06395 a48975c12c3dd0dc2827ab766bdde41f 363 TIGRFAM TIGR01681 HAD-SF-IIIC: HAD phosphatase, family IIIC 9 119 4.3E-21 T 29-03-2018 IPR010033 HAD-superfamily phosphatase, subfamily IIIC SMALA_RS06395 a48975c12c3dd0dc2827ab766bdde41f 363 Gene3D G3DSA:3.40.50.1000 7 113 9.3E-16 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS06395 a48975c12c3dd0dc2827ab766bdde41f 363 SUPERFAMILY SSF56784 8 110 1.32E-17 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS06395 a48975c12c3dd0dc2827ab766bdde41f 363 Pfam PF13419 Haloacid dehalogenase-like hydrolase 28 109 6.4E-6 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS06395 a48975c12c3dd0dc2827ab766bdde41f 363 TIGRFAM TIGR01686 FkbH: FkbH domain 6 317 1.9E-114 T 29-03-2018 IPR010037 FkbH domain SMALA_RS06395 a48975c12c3dd0dc2827ab766bdde41f 363 Gene3D G3DSA:3.40.630.30 183 318 1.4E-6 T 29-03-2018 SMALA_RS30415 4942977318518dee311bd6c5708cf7d7 1063 SMART SM00872 519 598 2.1E-35 T 29-03-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 SMALA_RS30415 4942977318518dee311bd6c5708cf7d7 1063 SUPERFAMILY SSF88688 518 618 1.63E-25 T 29-03-2018 IPR028995 Glycoside hydrolase families 57/38, central domain SMALA_RS30415 4942977318518dee311bd6c5708cf7d7 1063 Gene3D G3DSA:3.20.110.10 202 475 6.5E-79 T 29-03-2018 IPR027291 Glycoside hydrolase 38/57, N-terminal domain SMALA_RS30415 4942977318518dee311bd6c5708cf7d7 1063 SUPERFAMILY SSF74650 622 1060 2.13E-65 T 29-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 SMALA_RS30415 4942977318518dee311bd6c5708cf7d7 1063 Pfam PF09261 Alpha mannosidase middle domain 519 596 6.6E-27 T 29-03-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 SMALA_RS30415 4942977318518dee311bd6c5708cf7d7 1063 Pfam PF01074 Glycosyl hydrolases family 38 N-terminal domain 254 504 6.6E-84 T 29-03-2018 IPR000602 Glycoside hydrolase family 38, N-terminal domain GO:0004559|GO:0006013 SMALA_RS30415 4942977318518dee311bd6c5708cf7d7 1063 SUPERFAMILY SSF88713 247 517 9.34E-72 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 SMALA_RS30415 4942977318518dee311bd6c5708cf7d7 1063 Gene3D G3DSA:1.20.1270.50 518 625 1.7E-34 T 29-03-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 SMALA_RS30415 4942977318518dee311bd6c5708cf7d7 1063 Pfam PF07748 Glycosyl hydrolases family 38 C-terminal domain 658 1058 5.1E-68 T 29-03-2018 IPR011682 Glycosyl hydrolase family 38, C-terminal GO:0004559|GO:0006013 SMALA_RS40155 6ee07178c07df6ae7bc762cc2752fdc2 444 SUPERFAMILY SSF51679 1 432 1.44E-125 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS40155 6ee07178c07df6ae7bc762cc2752fdc2 444 Gene3D G3DSA:3.20.20.30 1 442 1.5E-100 T 29-03-2018 SMALA_RS40155 6ee07178c07df6ae7bc762cc2752fdc2 444 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 3 426 3.1E-161 T 29-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 SMALA_RS40155 6ee07178c07df6ae7bc762cc2752fdc2 444 PIRSF PIRSF000337 1 441 1.8E-162 T 29-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 SMALA_RS40155 6ee07178c07df6ae7bc762cc2752fdc2 444 Pfam PF00296 Luciferase-like monooxygenase 10 378 5.9E-61 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS34160 3fd609d36667465e6beda9c6a62afe53 146 Pfam PF01475 Ferric uptake regulator family 17 131 8.9E-19 T 29-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 SMALA_RS34160 3fd609d36667465e6beda9c6a62afe53 146 SUPERFAMILY SSF46785 11 138 7.94E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS34160 3fd609d36667465e6beda9c6a62afe53 146 Gene3D G3DSA:1.10.10.10 9 93 2.5E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS25140 adb4acbef97738043bfc8256e63125a1 576 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 23 370 9.7E-56 T 29-03-2018 IPR005674 CocE/Serine esterase GO:0016787 SMALA_RS25140 adb4acbef97738043bfc8256e63125a1 576 SUPERFAMILY SSF53474 6 348 1.12E-61 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS25140 adb4acbef97738043bfc8256e63125a1 576 SMART SM00939 318 569 2.7E-30 T 29-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 SMALA_RS25140 adb4acbef97738043bfc8256e63125a1 576 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 330 567 1.2E-26 T 29-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 SMALA_RS25140 adb4acbef97738043bfc8256e63125a1 576 Gene3D G3DSA:2.60.120.260 325 576 1.9E-41 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS25140 adb4acbef97738043bfc8256e63125a1 576 SUPERFAMILY SSF49785 352 574 8.71E-30 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS25140 adb4acbef97738043bfc8256e63125a1 576 Gene3D G3DSA:3.40.50.1820 4 324 1.2E-25 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS25140 adb4acbef97738043bfc8256e63125a1 576 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 23 305 5.2E-42 T 29-03-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 SMALA_RS25590 5081ae2fda36281275c0c6cfae827ee5 385 SUPERFAMILY SSF52540 49 301 3.43E-76 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS25590 5081ae2fda36281275c0c6cfae827ee5 385 SMART SM00382 86 279 6.4E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS25590 5081ae2fda36281275c0c6cfae827ee5 385 Gene3D G3DSA:3.40.50.300 46 384 3.7E-85 T 29-03-2018 SMALA_RS25590 5081ae2fda36281275c0c6cfae827ee5 385 ProSitePatterns PS00211 ABC transporters family signature. 202 216 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS25590 5081ae2fda36281275c0c6cfae827ee5 385 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 280 356 1.1E-22 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMALA_RS25590 5081ae2fda36281275c0c6cfae827ee5 385 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 282 348 3.1E-16 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMALA_RS25590 5081ae2fda36281275c0c6cfae827ee5 385 Pfam PF00005 ABC transporter 78 229 1.3E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS36475 0adb7ebdac2a2556f9e6e02ef0defb8d 467 Gene3D G3DSA:3.50.50.60 276 332 8.5E-14 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS36475 0adb7ebdac2a2556f9e6e02ef0defb8d 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 261 275 8.7E-55 T 29-03-2018 SMALA_RS36475 0adb7ebdac2a2556f9e6e02ef0defb8d 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 176 201 8.7E-55 T 29-03-2018 SMALA_RS36475 0adb7ebdac2a2556f9e6e02ef0defb8d 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 339 360 8.7E-55 T 29-03-2018 SMALA_RS36475 0adb7ebdac2a2556f9e6e02ef0defb8d 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 8.7E-55 T 29-03-2018 SMALA_RS36475 0adb7ebdac2a2556f9e6e02ef0defb8d 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 140 149 8.7E-55 T 29-03-2018 SMALA_RS36475 0adb7ebdac2a2556f9e6e02ef0defb8d 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 426 446 8.7E-55 T 29-03-2018 SMALA_RS36475 0adb7ebdac2a2556f9e6e02ef0defb8d 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 404 419 8.7E-55 T 29-03-2018 SMALA_RS36475 0adb7ebdac2a2556f9e6e02ef0defb8d 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 8.7E-55 T 29-03-2018 SMALA_RS36475 0adb7ebdac2a2556f9e6e02ef0defb8d 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 304 311 8.7E-55 T 29-03-2018 SMALA_RS36475 0adb7ebdac2a2556f9e6e02ef0defb8d 467 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 344 451 1.6E-24 T 29-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 SMALA_RS36475 0adb7ebdac2a2556f9e6e02ef0defb8d 467 Gene3D G3DSA:3.50.50.60 160 275 3.2E-19 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS36475 0adb7ebdac2a2556f9e6e02ef0defb8d 467 Gene3D G3DSA:3.30.390.30 333 461 9.3E-32 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SMALA_RS36475 0adb7ebdac2a2556f9e6e02ef0defb8d 467 PIRSF PIRSF000350 1 464 3.3E-66 T 29-03-2018 SMALA_RS36475 0adb7ebdac2a2556f9e6e02ef0defb8d 467 SUPERFAMILY SSF55424 341 460 3.44E-30 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SMALA_RS36475 0adb7ebdac2a2556f9e6e02ef0defb8d 467 Gene3D G3DSA:3.50.50.60 1 159 2.7E-24 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS36475 0adb7ebdac2a2556f9e6e02ef0defb8d 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 137 155 4.7E-34 T 29-03-2018 SMALA_RS36475 0adb7ebdac2a2556f9e6e02ef0defb8d 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 4.7E-34 T 29-03-2018 SMALA_RS36475 0adb7ebdac2a2556f9e6e02ef0defb8d 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 289 311 4.7E-34 T 29-03-2018 SMALA_RS36475 0adb7ebdac2a2556f9e6e02ef0defb8d 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 176 194 4.7E-34 T 29-03-2018 SMALA_RS36475 0adb7ebdac2a2556f9e6e02ef0defb8d 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 260 276 4.7E-34 T 29-03-2018 SMALA_RS36475 0adb7ebdac2a2556f9e6e02ef0defb8d 467 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 324 6.8E-56 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS36475 0adb7ebdac2a2556f9e6e02ef0defb8d 467 SUPERFAMILY SSF51905 2 333 1.4E-52 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS38345 1f8097a205634317777373be7cf4e114 648 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 67 419 7.8E-13 T 29-03-2018 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 SMALA_RS38345 1f8097a205634317777373be7cf4e114 648 Gene3D G3DSA:3.20.20.80 35 471 3.9E-35 T 29-03-2018 SMALA_RS38345 1f8097a205634317777373be7cf4e114 648 SUPERFAMILY SSF51445 234 422 6.41E-31 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS38345 1f8097a205634317777373be7cf4e114 648 SUPERFAMILY SSF51445 52 171 6.41E-31 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS12180 6207d0f8bb900fb465ab429cdbc485c6 215 SMART SM00855 3 157 3.3E-21 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SMALA_RS12180 6207d0f8bb900fb465ab429cdbc485c6 215 SUPERFAMILY SSF53254 4 195 3.19E-48 T 29-03-2018 IPR029033 Histidine phosphatase superfamily SMALA_RS12180 6207d0f8bb900fb465ab429cdbc485c6 215 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 196 1.9E-52 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SMALA_RS12180 6207d0f8bb900fb465ab429cdbc485c6 215 PIRSF PIRSF000709 125 186 5.6 T 29-03-2018 SMALA_RS12180 6207d0f8bb900fb465ab429cdbc485c6 215 PIRSF PIRSF000709 2 101 1.5E-5 T 29-03-2018 SMALA_RS12180 6207d0f8bb900fb465ab429cdbc485c6 215 Gene3D G3DSA:3.40.50.1240 1 204 9.2E-47 T 29-03-2018 IPR029033 Histidine phosphatase superfamily SMALA_RS27460 4d1e1d7efa33383d8e2a7b4dece37dea 76 Gene3D G3DSA:1.10.238.10 53 75 9.7E-4 T 29-03-2018 SMALA_RS27460 4d1e1d7efa33383d8e2a7b4dece37dea 76 Gene3D G3DSA:1.10.238.10 2 52 1.7E-16 T 29-03-2018 SMALA_RS27460 4d1e1d7efa33383d8e2a7b4dece37dea 76 SUPERFAMILY SSF47473 4 66 4.05E-17 T 29-03-2018 IPR011992 EF-hand domain pair SMALA_RS27460 4d1e1d7efa33383d8e2a7b4dece37dea 76 ProSitePatterns PS00018 EF-hand calcium-binding domain. 15 27 - T 29-03-2018 IPR018247 EF-Hand 1, calcium-binding site SMALA_RS27460 4d1e1d7efa33383d8e2a7b4dece37dea 76 SMART SM00054 6 34 2.4E-4 T 29-03-2018 IPR002048 EF-hand domain GO:0005509 SMALA_RS27460 4d1e1d7efa33383d8e2a7b4dece37dea 76 SMART SM00054 43 71 9.3 T 29-03-2018 IPR002048 EF-hand domain GO:0005509 SMALA_RS27460 4d1e1d7efa33383d8e2a7b4dece37dea 76 ProSitePatterns PS00018 EF-hand calcium-binding domain. 52 64 - T 29-03-2018 IPR018247 EF-Hand 1, calcium-binding site SMALA_RS27460 4d1e1d7efa33383d8e2a7b4dece37dea 76 Pfam PF13499 EF-hand domain pair 6 64 1.2E-10 T 29-03-2018 IPR002048 EF-hand domain GO:0005509 SMALA_RS06555 0b64ae221c63b703f666d141750e4c1d 405 Pfam PF07690 Major Facilitator Superfamily 30 356 1.7E-20 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS06555 0b64ae221c63b703f666d141750e4c1d 405 Gene3D G3DSA:1.20.1250.20 207 392 3.1E-18 T 29-03-2018 SMALA_RS06555 0b64ae221c63b703f666d141750e4c1d 405 SUPERFAMILY SSF103473 15 394 1.09E-44 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS06555 0b64ae221c63b703f666d141750e4c1d 405 Gene3D G3DSA:1.20.1250.20 13 206 1.9E-16 T 29-03-2018 SMALA_RS00425 ec61ba1d9537867cc625fd2e8adb1441 1136 SUPERFAMILY SSF56801 472 1002 6.8E-129 T 29-03-2018 SMALA_RS00425 ec61ba1d9537867cc625fd2e8adb1441 1136 Pfam PF13193 AMP-binding enzyme C-terminal domain 886 990 5.0E-9 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS00425 ec61ba1d9537867cc625fd2e8adb1441 1136 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1041 1056 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS00425 ec61ba1d9537867cc625fd2e8adb1441 1136 SUPERFAMILY SSF52777 195 439 1.56E-46 T 29-03-2018 SMALA_RS00425 ec61ba1d9537867cc625fd2e8adb1441 1136 SUPERFAMILY SSF52777 15 193 8.56E-40 T 29-03-2018 SMALA_RS00425 ec61ba1d9537867cc625fd2e8adb1441 1136 SMART SM00823 Phosphopantetheine attachment site 1017 1086 0.0082 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS00425 ec61ba1d9537867cc625fd2e8adb1441 1136 Gene3D G3DSA:3.30.559.10 5 211 1.3E-38 T 29-03-2018 SMALA_RS00425 ec61ba1d9537867cc625fd2e8adb1441 1136 ProSitePatterns PS00455 Putative AMP-binding domain signature. 615 626 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS00425 ec61ba1d9537867cc625fd2e8adb1441 1136 Gene3D G3DSA:3.40.50.980 470 620 8.0E-41 T 29-03-2018 SMALA_RS00425 ec61ba1d9537867cc625fd2e8adb1441 1136 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 500 902 2.5E-113 T 29-03-2018 IPR010071 Amino acid adenylation domain SMALA_RS00425 ec61ba1d9537867cc625fd2e8adb1441 1136 Gene3D G3DSA:2.30.38.10 789 871 5.4E-22 T 29-03-2018 SMALA_RS00425 ec61ba1d9537867cc625fd2e8adb1441 1136 Pfam PF00550 Phosphopantetheine attachment site 1020 1081 5.3E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS00425 ec61ba1d9537867cc625fd2e8adb1441 1136 Gene3D G3DSA:3.40.50.980 621 784 1.0E-26 T 29-03-2018 SMALA_RS00425 ec61ba1d9537867cc625fd2e8adb1441 1136 SUPERFAMILY SSF47336 1015 1081 7.2E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS00425 ec61ba1d9537867cc625fd2e8adb1441 1136 Gene3D G3DSA:3.30.300.30 873 1023 1.0E-32 T 29-03-2018 SMALA_RS00425 ec61ba1d9537867cc625fd2e8adb1441 1136 Gene3D G3DSA:1.10.1200.10 1024 1129 3.3E-16 T 29-03-2018 SMALA_RS00425 ec61ba1d9537867cc625fd2e8adb1441 1136 Pfam PF00668 Condensation domain 10 446 3.9E-62 T 29-03-2018 IPR001242 Condensation domain SMALA_RS00425 ec61ba1d9537867cc625fd2e8adb1441 1136 Pfam PF00501 AMP-binding enzyme 478 878 7.0E-78 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS23600 ffb7428eee845fc108deddfab023e1bb 294 Gene3D G3DSA:2.40.30.10 10 140 7.5E-35 T 29-03-2018 SMALA_RS23600 ffb7428eee845fc108deddfab023e1bb 294 Gene3D G3DSA:3.40.50.80 147 289 9.9E-51 T 29-03-2018 SMALA_RS23600 ffb7428eee845fc108deddfab023e1bb 294 SUPERFAMILY SSF63380 10 138 5.67E-10 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 SMALA_RS23600 ffb7428eee845fc108deddfab023e1bb 294 Pfam PF08021 Siderophore-interacting FAD-binding domain 21 140 1.2E-40 T 29-03-2018 IPR013113 FAD-binding 9, siderophore-interacting SMALA_RS23600 ffb7428eee845fc108deddfab023e1bb 294 Pfam PF04954 Siderophore-interacting protein 154 274 1.2E-42 T 29-03-2018 IPR007037 Siderophore-interacting protein SMALA_RS28195 2d49b9cd8f5380722450619651cd85f1 540 SMART SM00382 235 419 1.4E-6 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS28195 2d49b9cd8f5380722450619651cd85f1 540 SUPERFAMILY SSF54211 2 170 2.81E-36 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SMALA_RS28195 2d49b9cd8f5380722450619651cd85f1 540 Gene3D G3DSA:3.30.230.10 2 186 1.3E-43 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SMALA_RS28195 2d49b9cd8f5380722450619651cd85f1 540 Gene3D G3DSA:3.40.50.300 213 473 2.4E-20 T 29-03-2018 SMALA_RS28195 2d49b9cd8f5380722450619651cd85f1 540 SUPERFAMILY SSF52540 489 526 3.4E-39 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS28195 2d49b9cd8f5380722450619651cd85f1 540 SUPERFAMILY SSF52540 215 456 3.4E-39 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS28195 2d49b9cd8f5380722450619651cd85f1 540 Pfam PF13541 Subunit ChlI of Mg-chelatase 21 142 1.0E-37 T 29-03-2018 SMALA_RS28195 2d49b9cd8f5380722450619651cd85f1 540 Pfam PF01078 Magnesium chelatase, subunit ChlI 215 422 1.3E-86 T 29-03-2018 IPR000523 Magnesium chelatase ChlI domain SMALA_RS28195 2d49b9cd8f5380722450619651cd85f1 540 Pfam PF13335 Magnesium chelatase, subunit ChlI C-terminal 431 526 1.2E-22 T 29-03-2018 IPR025158 Mg chelatase-related protein, C-terminal domain SMALA_RS10650 8c99a77d9ef7db3ab6b3be64519d5525 517 SUPERFAMILY SSF52949 17 149 7.06E-24 T 29-03-2018 SMALA_RS10650 8c99a77d9ef7db3ab6b3be64519d5525 517 Gene3D G3DSA:3.40.220.10 1 183 2.2E-48 T 29-03-2018 SMALA_RS10650 8c99a77d9ef7db3ab6b3be64519d5525 517 SUPERFAMILY SSF53187 194 509 2.62E-111 T 29-03-2018 SMALA_RS10650 8c99a77d9ef7db3ab6b3be64519d5525 517 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 199 505 6.7E-118 T 29-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 SMALA_RS10650 8c99a77d9ef7db3ab6b3be64519d5525 517 Gene3D G3DSA:3.40.630.10 184 516 2.9E-131 T 29-03-2018 SMALA_RS10650 8c99a77d9ef7db3ab6b3be64519d5525 517 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 359 366 - T 29-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 SMALA_RS10650 8c99a77d9ef7db3ab6b3be64519d5525 517 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 4 513 33.74 T 29-03-2018 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 SMALA_RS10650 8c99a77d9ef7db3ab6b3be64519d5525 517 PRINTS PR00481 Cytosol aminopeptidase signature 333 354 7.1E-50 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 SMALA_RS10650 8c99a77d9ef7db3ab6b3be64519d5525 517 PRINTS PR00481 Cytosol aminopeptidase signature 355 375 7.1E-50 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 SMALA_RS10650 8c99a77d9ef7db3ab6b3be64519d5525 517 PRINTS PR00481 Cytosol aminopeptidase signature 274 291 7.1E-50 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 SMALA_RS10650 8c99a77d9ef7db3ab6b3be64519d5525 517 PRINTS PR00481 Cytosol aminopeptidase signature 383 398 7.1E-50 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 SMALA_RS10650 8c99a77d9ef7db3ab6b3be64519d5525 517 PRINTS PR00481 Cytosol aminopeptidase signature 296 317 7.1E-50 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 SMALA_RS10650 8c99a77d9ef7db3ab6b3be64519d5525 517 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 20 142 5.1E-23 T 29-03-2018 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 SMALA_RS28560 5b0b733633b55217b66df18bb72f687b 245 Gene3D G3DSA:1.10.287.1060 2 154 2.1E-4 T 29-03-2018 SMALA_RS30395 3e39c73a16594284a4ca25ff10d6c840 402 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 49 388 2.1E-70 T 29-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase SMALA_RS30395 3e39c73a16594284a4ca25ff10d6c840 402 PIRSF PIRSF000390 26 395 1.3E-57 T 29-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase SMALA_RS30395 3e39c73a16594284a4ca25ff10d6c840 402 Gene3D G3DSA:3.90.1150.10 259 401 3.0E-23 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS30395 3e39c73a16594284a4ca25ff10d6c840 402 SUPERFAMILY SSF53383 28 390 5.33E-71 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS30395 3e39c73a16594284a4ca25ff10d6c840 402 Gene3D G3DSA:3.40.640.10 26 258 8.4E-34 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS41030 5d4ec476966ffc1de00e8ad5dd534344 112 Pfam PF01638 HxlR-like helix-turn-helix 18 104 2.3E-22 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type SMALA_RS41030 5d4ec476966ffc1de00e8ad5dd534344 112 Gene3D G3DSA:1.10.10.10 16 112 3.2E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS41030 5d4ec476966ffc1de00e8ad5dd534344 112 SUPERFAMILY SSF46785 4 109 1.16E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS19175 b337f6176d41c00cb7b189314ac609db 1516 Gene3D G3DSA:3.30.565.10 364 543 1.8E-13 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS19175 b337f6176d41c00cb7b189314ac609db 1516 SUPERFAMILY SSF55874 391 537 3.68E-7 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS19175 b337f6176d41c00cb7b189314ac609db 1516 SUPERFAMILY SSF55785 10 108 1.24E-10 T 29-03-2018 IPR000014 PAS domain SMALA_RS19175 b337f6176d41c00cb7b189314ac609db 1516 Gene3D G3DSA:3.30.450.20 9 146 2.6E-18 T 29-03-2018 SMALA_RS19175 b337f6176d41c00cb7b189314ac609db 1516 SMART SM00448 1392 1506 0.0055 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS19175 b337f6176d41c00cb7b189314ac609db 1516 Pfam PF00072 Response regulator receiver domain 1394 1478 4.7E-5 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS19175 b337f6176d41c00cb7b189314ac609db 1516 SUPERFAMILY SSF52172 1388 1478 1.22E-11 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS19175 b337f6176d41c00cb7b189314ac609db 1516 Pfam PF13188 PAS domain 10 65 0.0047 T 29-03-2018 IPR000014 PAS domain SMALA_RS19175 b337f6176d41c00cb7b189314ac609db 1516 SUPERFAMILY SSF47384 317 402 1.41E-6 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS19175 b337f6176d41c00cb7b189314ac609db 1516 Pfam PF00989 PAS fold 151 262 1.2E-14 T 29-03-2018 IPR013767 PAS fold GO:0006355 SMALA_RS19175 b337f6176d41c00cb7b189314ac609db 1516 Gene3D G3DSA:3.40.50.2300 1375 1514 4.9E-11 T 29-03-2018 SMALA_RS19175 b337f6176d41c00cb7b189314ac609db 1516 SUPERFAMILY SSF55785 137 262 3.66E-18 T 29-03-2018 IPR000014 PAS domain SMALA_RS19175 b337f6176d41c00cb7b189314ac609db 1516 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 10 113 5.4E-7 T 29-03-2018 IPR000014 PAS domain SMALA_RS19175 b337f6176d41c00cb7b189314ac609db 1516 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 151 260 2.2E-10 T 29-03-2018 IPR000014 PAS domain SMALA_RS19175 b337f6176d41c00cb7b189314ac609db 1516 SMART SM00091 10 76 3.7E-6 T 29-03-2018 IPR000014 PAS domain SMALA_RS19175 b337f6176d41c00cb7b189314ac609db 1516 SMART SM00091 147 213 5.1E-7 T 29-03-2018 IPR000014 PAS domain SMALA_RS19175 b337f6176d41c00cb7b189314ac609db 1516 Gene3D G3DSA:3.30.450.20 147 280 1.1E-23 T 29-03-2018 SMALA_RS27425 6f33f7bdcdb89d774fe63ef220fe1e44 627 Gene3D G3DSA:1.20.1560.10 43 372 3.4E-56 T 29-03-2018 SMALA_RS27425 6f33f7bdcdb89d774fe63ef220fe1e44 627 Pfam PF00664 ABC transporter transmembrane region 63 330 1.2E-32 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMALA_RS27425 6f33f7bdcdb89d774fe63ef220fe1e44 627 Gene3D G3DSA:3.40.50.300 384 625 1.5E-66 T 29-03-2018 SMALA_RS27425 6f33f7bdcdb89d774fe63ef220fe1e44 627 SUPERFAMILY SSF52540 383 621 7.44E-81 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS27425 6f33f7bdcdb89d774fe63ef220fe1e44 627 ProSitePatterns PS00211 ABC transporters family signature. 524 538 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS27425 6f33f7bdcdb89d774fe63ef220fe1e44 627 Pfam PF00005 ABC transporter 406 552 1.6E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS27425 6f33f7bdcdb89d774fe63ef220fe1e44 627 SUPERFAMILY SSF90123 51 372 1.96E-66 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMALA_RS27425 6f33f7bdcdb89d774fe63ef220fe1e44 627 SMART SM00382 412 598 4.6E-18 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS30290 e30a7e0c3fd7a7d6a3cab7b06672adfb 375 Gene3D G3DSA:1.10.101.10 192 257 3.7E-12 T 29-03-2018 IPR002477 Peptidoglycan binding-like SMALA_RS30290 e30a7e0c3fd7a7d6a3cab7b06672adfb 375 Gene3D G3DSA:1.10.530.10 258 367 2.0E-7 T 29-03-2018 SMALA_RS30290 e30a7e0c3fd7a7d6a3cab7b06672adfb 375 Gene3D G3DSA:1.10.260.40 1 83 3.7E-5 T 29-03-2018 SMALA_RS30290 e30a7e0c3fd7a7d6a3cab7b06672adfb 375 SUPERFAMILY SSF53955 285 365 7.7E-6 T 29-03-2018 IPR023346 Lysozyme-like domain SMALA_RS30290 e30a7e0c3fd7a7d6a3cab7b06672adfb 375 Pfam PF01471 Putative peptidoglycan binding domain 208 259 4.6E-9 T 29-03-2018 IPR002477 Peptidoglycan binding-like SMALA_RS30290 e30a7e0c3fd7a7d6a3cab7b06672adfb 375 SUPERFAMILY SSF47413 1 73 3.31E-5 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS30290 e30a7e0c3fd7a7d6a3cab7b06672adfb 375 Pfam PF13560 Helix-turn-helix domain 1 59 5.4E-7 T 29-03-2018 SMALA_RS30290 e30a7e0c3fd7a7d6a3cab7b06672adfb 375 SUPERFAMILY SSF47090 197 263 2.62E-13 T 29-03-2018 IPR002477 Peptidoglycan binding-like SMALA_RS40055 82338eb05875d25122d0fc1eeba99736 344 Gene3D G3DSA:3.90.230.10 121 343 2.1E-17 T 29-03-2018 SMALA_RS40055 82338eb05875d25122d0fc1eeba99736 344 Gene3D G3DSA:3.40.350.10 11 101 0.0019 T 29-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal SMALA_RS40055 82338eb05875d25122d0fc1eeba99736 344 SUPERFAMILY SSF55920 122 332 1.44E-17 T 29-03-2018 IPR000994 Peptidase M24 SMALA_RS40055 82338eb05875d25122d0fc1eeba99736 344 Pfam PF00557 Metallopeptidase family M24 129 327 3.3E-10 T 29-03-2018 IPR000994 Peptidase M24 SMALA_RS23195 36ee1d97df00625167dcf6f7097d1db6 260 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 253 7.6E-67 T 29-03-2018 SMALA_RS23195 36ee1d97df00625167dcf6f7097d1db6 260 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMALA_RS23195 36ee1d97df00625167dcf6f7097d1db6 260 SUPERFAMILY SSF51735 5 254 1.05E-81 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS23195 36ee1d97df00625167dcf6f7097d1db6 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 3.3E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS23195 36ee1d97df00625167dcf6f7097d1db6 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 3.3E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS23195 36ee1d97df00625167dcf6f7097d1db6 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 3.3E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS23195 36ee1d97df00625167dcf6f7097d1db6 260 Gene3D G3DSA:3.40.50.720 45 259 6.5E-63 T 29-03-2018 SMALA_RS23195 36ee1d97df00625167dcf6f7097d1db6 260 Gene3D G3DSA:3.40.50.720 1 44 2.5E-8 T 29-03-2018 SMALA_RS23195 36ee1d97df00625167dcf6f7097d1db6 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 6.2E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS23195 36ee1d97df00625167dcf6f7097d1db6 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 6.2E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS23195 36ee1d97df00625167dcf6f7097d1db6 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 6.2E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS23195 36ee1d97df00625167dcf6f7097d1db6 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 6.2E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS23195 36ee1d97df00625167dcf6f7097d1db6 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 6.2E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS23195 36ee1d97df00625167dcf6f7097d1db6 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 6.2E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS17715 f2bfcb8a1df84637691d737f2cadb344 1373 Gene3D G3DSA:3.40.50.300 160 190 9.7E-4 T 29-03-2018 SMALA_RS17715 f2bfcb8a1df84637691d737f2cadb344 1373 Gene3D G3DSA:2.130.10.10 1050 1140 1.3E-16 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMALA_RS17715 f2bfcb8a1df84637691d737f2cadb344 1373 Gene3D G3DSA:2.140.10.30 1141 1207 4.6E-22 T 29-03-2018 SMALA_RS17715 f2bfcb8a1df84637691d737f2cadb344 1373 Gene3D G3DSA:2.40.10.120 762 808 6.7E-15 T 29-03-2018 SMALA_RS17715 f2bfcb8a1df84637691d737f2cadb344 1373 Gene3D G3DSA:2.40.10.120 1208 1240 4.9E-14 T 29-03-2018 SMALA_RS17715 f2bfcb8a1df84637691d737f2cadb344 1373 Gene3D G3DSA:2.40.10.120 709 761 1.1E-14 T 29-03-2018 SMALA_RS17715 f2bfcb8a1df84637691d737f2cadb344 1373 Gene3D G3DSA:2.40.10.120 1311 1345 0.015 T 29-03-2018 SMALA_RS17715 f2bfcb8a1df84637691d737f2cadb344 1373 Gene3D G3DSA:2.40.10.120 814 843 7.7E-9 T 29-03-2018 SMALA_RS17715 f2bfcb8a1df84637691d737f2cadb344 1373 Pfam PF00400 WD domain, G-beta repeat 1256 1289 6.8E-8 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 SMALA_RS17715 f2bfcb8a1df84637691d737f2cadb344 1373 Pfam PF00400 WD domain, G-beta repeat 1163 1197 8.3E-9 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 SMALA_RS17715 f2bfcb8a1df84637691d737f2cadb344 1373 Pfam PF00400 WD domain, G-beta repeat 763 797 9.7E-9 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 SMALA_RS17715 f2bfcb8a1df84637691d737f2cadb344 1373 Pfam PF00400 WD domain, G-beta repeat 1211 1243 1.7E-8 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 SMALA_RS17715 f2bfcb8a1df84637691d737f2cadb344 1373 Pfam PF00400 WD domain, G-beta repeat 947 980 6.9E-7 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 SMALA_RS17715 f2bfcb8a1df84637691d737f2cadb344 1373 Pfam PF00400 WD domain, G-beta repeat 853 888 5.1E-9 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 SMALA_RS17715 f2bfcb8a1df84637691d737f2cadb344 1373 Pfam PF00400 WD domain, G-beta repeat 719 751 4.7E-6 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 SMALA_RS17715 f2bfcb8a1df84637691d737f2cadb344 1373 Pfam PF00400 WD domain, G-beta repeat 821 843 0.13 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 SMALA_RS17715 f2bfcb8a1df84637691d737f2cadb344 1373 Pfam PF00400 WD domain, G-beta repeat 1003 1026 0.0016 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 SMALA_RS17715 f2bfcb8a1df84637691d737f2cadb344 1373 Pfam PF00400 WD domain, G-beta repeat 900 934 3.6E-10 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 SMALA_RS17715 f2bfcb8a1df84637691d737f2cadb344 1373 Gene3D G3DSA:3.40.50.300 191 555 1.7E-4 T 29-03-2018 SMALA_RS17715 f2bfcb8a1df84637691d737f2cadb344 1373 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 1092 1106 - T 29-03-2018 IPR019775 WD40 repeat, conserved site SMALA_RS17715 f2bfcb8a1df84637691d737f2cadb344 1373 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 875 889 - T 29-03-2018 IPR019775 WD40 repeat, conserved site SMALA_RS17715 f2bfcb8a1df84637691d737f2cadb344 1373 Gene3D G3DSA:2.140.10.10 957 1049 1.3E-29 T 29-03-2018 SMALA_RS17715 f2bfcb8a1df84637691d737f2cadb344 1373 SUPERFAMILY SSF52540 152 233 5.16E-7 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS17715 f2bfcb8a1df84637691d737f2cadb344 1373 SUPERFAMILY SSF52540 317 424 5.16E-7 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS17715 f2bfcb8a1df84637691d737f2cadb344 1373 Gene3D G3DSA:2.120.10.30 844 956 4.6E-35 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like SMALA_RS17715 f2bfcb8a1df84637691d737f2cadb344 1373 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 921 935 - T 29-03-2018 IPR019775 WD40 repeat, conserved site SMALA_RS17715 f2bfcb8a1df84637691d737f2cadb344 1373 SUPERFAMILY SSF50978 1074 1107 2.2E-84 T 29-03-2018 IPR017986 WD40-repeat-containing domain GO:0005515 SMALA_RS17715 f2bfcb8a1df84637691d737f2cadb344 1373 SUPERFAMILY SSF50978 712 1041 2.2E-84 T 29-03-2018 IPR017986 WD40-repeat-containing domain GO:0005515 SMALA_RS17715 f2bfcb8a1df84637691d737f2cadb344 1373 PRINTS PR00320 G protein beta WD-40 repeat signature 1230 1244 7.0E-9 T 29-03-2018 IPR020472 G-protein beta WD-40 repeat SMALA_RS17715 f2bfcb8a1df84637691d737f2cadb344 1373 PRINTS PR00320 G protein beta WD-40 repeat signature 784 798 7.0E-9 T 29-03-2018 IPR020472 G-protein beta WD-40 repeat SMALA_RS17715 f2bfcb8a1df84637691d737f2cadb344 1373 PRINTS PR00320 G protein beta WD-40 repeat signature 921 935 7.0E-9 T 29-03-2018 IPR020472 G-protein beta WD-40 repeat SMALA_RS17715 f2bfcb8a1df84637691d737f2cadb344 1373 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 967 981 - T 29-03-2018 IPR019775 WD40 repeat, conserved site SMALA_RS17715 f2bfcb8a1df84637691d737f2cadb344 1373 SMART SM00320 804 843 0.002 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 SMALA_RS17715 f2bfcb8a1df84637691d737f2cadb344 1373 SMART SM00320 758 797 9.4E-11 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 SMALA_RS17715 f2bfcb8a1df84637691d737f2cadb344 1373 SMART SM00320 1296 1335 7.3 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 SMALA_RS17715 f2bfcb8a1df84637691d737f2cadb344 1373 SMART SM00320 1204 1243 4.1E-8 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 SMALA_RS17715 f2bfcb8a1df84637691d737f2cadb344 1373 SMART SM00320 1250 1289 1.5E-10 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 SMALA_RS17715 f2bfcb8a1df84637691d737f2cadb344 1373 SMART SM00320 987 1026 3.7E-5 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 SMALA_RS17715 f2bfcb8a1df84637691d737f2cadb344 1373 SMART SM00320 895 934 6.7E-12 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 SMALA_RS17715 f2bfcb8a1df84637691d737f2cadb344 1373 SMART SM00320 1029 1059 40.0 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 SMALA_RS17715 f2bfcb8a1df84637691d737f2cadb344 1373 SMART SM00320 941 980 7.7E-9 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 SMALA_RS17715 f2bfcb8a1df84637691d737f2cadb344 1373 SMART SM00320 1158 1197 2.4E-10 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 SMALA_RS17715 f2bfcb8a1df84637691d737f2cadb344 1373 SMART SM00320 712 751 5.3E-9 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 SMALA_RS17715 f2bfcb8a1df84637691d737f2cadb344 1373 SMART SM00320 1066 1105 1.5 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 SMALA_RS17715 f2bfcb8a1df84637691d737f2cadb344 1373 SMART SM00320 849 888 5.7E-11 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 SMALA_RS17715 f2bfcb8a1df84637691d737f2cadb344 1373 SMART SM00320 1114 1151 0.48 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 SMALA_RS17715 f2bfcb8a1df84637691d737f2cadb344 1373 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 1046 1060 - T 29-03-2018 IPR019775 WD40 repeat, conserved site SMALA_RS17715 f2bfcb8a1df84637691d737f2cadb344 1373 SUPERFAMILY SSF101908 1042 1340 6.8E-60 T 29-03-2018 SMALA_RS17715 f2bfcb8a1df84637691d737f2cadb344 1373 Gene3D G3DSA:1.10.10.670 1241 1308 1.2E-18 T 29-03-2018 SMALA_RS17715 f2bfcb8a1df84637691d737f2cadb344 1373 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 1138 1152 - T 29-03-2018 IPR019775 WD40 repeat, conserved site SMALA_RS17715 f2bfcb8a1df84637691d737f2cadb344 1373 Pfam PF13191 AAA ATPase domain 154 346 2.4E-9 T 29-03-2018 SMALA_RS17715 f2bfcb8a1df84637691d737f2cadb344 1373 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 1230 1244 - T 29-03-2018 IPR019775 WD40 repeat, conserved site SMALA_RS17715 f2bfcb8a1df84637691d737f2cadb344 1373 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 738 752 - T 29-03-2018 IPR019775 WD40 repeat, conserved site SMALA_RS17715 f2bfcb8a1df84637691d737f2cadb344 1373 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 1276 1290 - T 29-03-2018 IPR019775 WD40 repeat, conserved site SMALA_RS17715 f2bfcb8a1df84637691d737f2cadb344 1373 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 784 798 - T 29-03-2018 IPR019775 WD40 repeat, conserved site SMALA_RS30200 7078cf579fbe4ea10902d6f9747c2479 406 Gene3D G3DSA:3.30.70.80 47 129 1.5E-18 T 29-03-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 SMALA_RS30200 7078cf579fbe4ea10902d6f9747c2479 406 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 163 174 - T 29-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site SMALA_RS30200 7078cf579fbe4ea10902d6f9747c2479 406 Pfam PF05922 Peptidase inhibitor I9 76 125 1.1E-6 T 29-03-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 SMALA_RS30200 7078cf579fbe4ea10902d6f9747c2479 406 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 200 210 - T 29-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site SMALA_RS30200 7078cf579fbe4ea10902d6f9747c2479 406 SUPERFAMILY SSF54897 55 125 2.49E-10 T 29-03-2018 IPR009020 Protease propeptides/proteinase inhibitor I9 SMALA_RS30200 7078cf579fbe4ea10902d6f9747c2479 406 SUPERFAMILY SSF52743 132 387 1.44E-75 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMALA_RS30200 7078cf579fbe4ea10902d6f9747c2479 406 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 350 360 - T 29-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site SMALA_RS30200 7078cf579fbe4ea10902d6f9747c2479 406 Gene3D G3DSA:3.40.50.200 130 405 2.5E-78 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMALA_RS30200 7078cf579fbe4ea10902d6f9747c2479 406 PRINTS PR00723 Subtilisin serine protease family (S8) signature 158 177 2.1E-20 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related SMALA_RS30200 7078cf579fbe4ea10902d6f9747c2479 406 PRINTS PR00723 Subtilisin serine protease family (S8) signature 349 365 2.1E-20 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related SMALA_RS30200 7078cf579fbe4ea10902d6f9747c2479 406 PRINTS PR00723 Subtilisin serine protease family (S8) signature 196 209 2.1E-20 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related SMALA_RS30200 7078cf579fbe4ea10902d6f9747c2479 406 Pfam PF00082 Subtilase family 158 386 3.9E-43 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMALA_RS30430 48e0bc660c78c1ad5f78f4fd6bb89367 229 SUPERFAMILY SSF46785 26 106 5.17E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS30430 48e0bc660c78c1ad5f78f4fd6bb89367 229 Pfam PF07729 FCD domain 102 226 5.2E-18 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS30430 48e0bc660c78c1ad5f78f4fd6bb89367 229 SMART SM00345 34 92 1.1E-10 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS30430 48e0bc660c78c1ad5f78f4fd6bb89367 229 SUPERFAMILY SSF48008 99 226 1.62E-18 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS30430 48e0bc660c78c1ad5f78f4fd6bb89367 229 Gene3D G3DSA:1.20.120.530 89 229 3.2E-24 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS30430 48e0bc660c78c1ad5f78f4fd6bb89367 229 SMART SM00895 102 227 3.5E-12 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS30430 48e0bc660c78c1ad5f78f4fd6bb89367 229 Gene3D G3DSA:1.10.10.10 15 88 2.3E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS30430 48e0bc660c78c1ad5f78f4fd6bb89367 229 Pfam PF00392 Bacterial regulatory proteins, gntR family 33 92 6.6E-14 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS14160 fad0db128fbbd5fb93b5c9dd420bb373 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 2.5E-31 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMALA_RS14160 fad0db128fbbd5fb93b5c9dd420bb373 67 PIRSF PIRSF002599 1 67 1.6E-26 T 29-03-2018 IPR012156 Cold shock, CspA GO:0003676 SMALA_RS14160 fad0db128fbbd5fb93b5c9dd420bb373 67 SUPERFAMILY SSF50249 1 66 2.14E-25 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMALA_RS14160 fad0db128fbbd5fb93b5c9dd420bb373 67 SMART SM00357 3 67 2.3E-31 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 SMALA_RS14160 fad0db128fbbd5fb93b5c9dd420bb373 67 Gene3D G3DSA:2.40.50.140 1 67 4.5E-28 T 29-03-2018 SMALA_RS14160 fad0db128fbbd5fb93b5c9dd420bb373 67 PRINTS PR00050 Cold shock protein signature 4 19 7.9E-18 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMALA_RS14160 fad0db128fbbd5fb93b5c9dd420bb373 67 PRINTS PR00050 Cold shock protein signature 25 34 7.9E-18 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMALA_RS14160 fad0db128fbbd5fb93b5c9dd420bb373 67 PRINTS PR00050 Cold shock protein signature 40 58 7.9E-18 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMALA_RS14160 fad0db128fbbd5fb93b5c9dd420bb373 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 29-03-2018 IPR019844 Cold-shock conserved site SMALA_RS23065 1f389028346ecafe25c5d6cf7797ac18 444 Pfam PF07690 Major Facilitator Superfamily 280 431 9.4E-11 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS23065 1f389028346ecafe25c5d6cf7797ac18 444 Pfam PF07690 Major Facilitator Superfamily 39 265 1.4E-21 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS23065 1f389028346ecafe25c5d6cf7797ac18 444 SUPERFAMILY SSF103473 16 433 1.57E-61 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS23065 1f389028346ecafe25c5d6cf7797ac18 444 Gene3D G3DSA:1.20.1250.20 11 219 1.1E-24 T 29-03-2018 SMALA_RS23065 1f389028346ecafe25c5d6cf7797ac18 444 Gene3D G3DSA:1.20.1250.20 239 437 1.5E-21 T 29-03-2018 SMALA_RS03145 6c9b2c516b83e5eeb2f37e66ecb614ae 179 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 50 58 - T 29-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 SMALA_RS03145 6c9b2c516b83e5eeb2f37e66ecb614ae 179 SUPERFAMILY SSF54292 14 89 8.52E-25 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SMALA_RS03145 6c9b2c516b83e5eeb2f37e66ecb614ae 179 SUPERFAMILY SSF47741 97 165 1.22E-27 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 SMALA_RS03145 6c9b2c516b83e5eeb2f37e66ecb614ae 179 Gene3D G3DSA:1.10.150.120 86 179 9.9E-31 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 SMALA_RS03145 6c9b2c516b83e5eeb2f37e66ecb614ae 179 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 17 70 3.2E-7 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SMALA_RS03145 6c9b2c516b83e5eeb2f37e66ecb614ae 179 Pfam PF01799 [2Fe-2S] binding domain 84 158 4.0E-27 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 SMALA_RS03145 6c9b2c516b83e5eeb2f37e66ecb614ae 179 Gene3D G3DSA:3.10.20.30 9 85 2.3E-25 T 29-03-2018 IPR012675 Beta-grasp domain SMALA_RS06200 477c168795fe2e1dd23ee8713f13e0bd 890 SUPERFAMILY SSF52540 315 549 5.74E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS06200 477c168795fe2e1dd23ee8713f13e0bd 890 SMART SM00382 345 539 8.0E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS06200 477c168795fe2e1dd23ee8713f13e0bd 890 Gene3D G3DSA:2.60.200.20 6 103 6.3E-24 T 29-03-2018 SMALA_RS06200 477c168795fe2e1dd23ee8713f13e0bd 890 Pfam PF00005 ABC transporter 336 483 3.4E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS06200 477c168795fe2e1dd23ee8713f13e0bd 890 ProSitePatterns PS00211 ABC transporters family signature. 455 469 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS06200 477c168795fe2e1dd23ee8713f13e0bd 890 Gene3D G3DSA:3.40.50.300 317 589 3.0E-69 T 29-03-2018 SMALA_RS06200 477c168795fe2e1dd23ee8713f13e0bd 890 SUPERFAMILY SSF49879 198 326 8.61E-25 T 29-03-2018 IPR008984 SMAD/FHA domain GO:0005515 SMALA_RS06200 477c168795fe2e1dd23ee8713f13e0bd 890 Pfam PF00498 FHA domain 21 84 1.9E-17 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 SMALA_RS06200 477c168795fe2e1dd23ee8713f13e0bd 890 Pfam PF00498 FHA domain 235 286 3.2E-14 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 SMALA_RS06200 477c168795fe2e1dd23ee8713f13e0bd 890 Gene3D G3DSA:2.60.200.20 199 312 2.3E-21 T 29-03-2018 SMALA_RS06200 477c168795fe2e1dd23ee8713f13e0bd 890 Pfam PF01061 ABC-2 type transporter 613 825 3.1E-18 T 29-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 SMALA_RS06200 477c168795fe2e1dd23ee8713f13e0bd 890 SUPERFAMILY SSF49879 9 87 1.26E-23 T 29-03-2018 IPR008984 SMAD/FHA domain GO:0005515 SMALA_RS06200 477c168795fe2e1dd23ee8713f13e0bd 890 SMART SM00240 20 70 3.8E-12 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 SMALA_RS06200 477c168795fe2e1dd23ee8713f13e0bd 890 SMART SM00240 233 284 2.0E-14 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 SMALA_RS22795 1e1b1e97a5a794ae326e9407038d204e 384 Gene3D G3DSA:3.20.20.10 5 231 8.0E-47 T 29-03-2018 IPR029066 PLP-binding barrel SMALA_RS22795 1e1b1e97a5a794ae326e9407038d204e 384 SMART SM01005 249 376 9.4E-63 T 29-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SMALA_RS22795 1e1b1e97a5a794ae326e9407038d204e 384 SUPERFAMILY SSF51419 12 250 9.01E-62 T 29-03-2018 IPR029066 PLP-binding barrel SMALA_RS22795 1e1b1e97a5a794ae326e9407038d204e 384 PRINTS PR00992 Alanine racemase signature 127 139 1.8E-56 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SMALA_RS22795 1e1b1e97a5a794ae326e9407038d204e 384 PRINTS PR00992 Alanine racemase signature 282 297 1.8E-56 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SMALA_RS22795 1e1b1e97a5a794ae326e9407038d204e 384 PRINTS PR00992 Alanine racemase signature 66 84 1.8E-56 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SMALA_RS22795 1e1b1e97a5a794ae326e9407038d204e 384 PRINTS PR00992 Alanine racemase signature 164 175 1.8E-56 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SMALA_RS22795 1e1b1e97a5a794ae326e9407038d204e 384 PRINTS PR00992 Alanine racemase signature 207 234 1.8E-56 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SMALA_RS22795 1e1b1e97a5a794ae326e9407038d204e 384 PRINTS PR00992 Alanine racemase signature 358 371 1.8E-56 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SMALA_RS22795 1e1b1e97a5a794ae326e9407038d204e 384 PRINTS PR00992 Alanine racemase signature 265 280 1.8E-56 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SMALA_RS22795 1e1b1e97a5a794ae326e9407038d204e 384 PRINTS PR00992 Alanine racemase signature 303 320 1.8E-56 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SMALA_RS22795 1e1b1e97a5a794ae326e9407038d204e 384 PRINTS PR00992 Alanine racemase signature 30 46 1.8E-56 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SMALA_RS22795 1e1b1e97a5a794ae326e9407038d204e 384 Pfam PF01168 Alanine racemase, N-terminal domain 12 234 2.3E-62 T 29-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SMALA_RS22795 1e1b1e97a5a794ae326e9407038d204e 384 Hamap MF_01201 Alanine racemase. 5 376 31.334 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SMALA_RS22795 1e1b1e97a5a794ae326e9407038d204e 384 TIGRFAM TIGR00492 alr: alanine racemase 9 376 2.2E-88 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SMALA_RS22795 1e1b1e97a5a794ae326e9407038d204e 384 Gene3D G3DSA:2.40.37.10 232 383 5.0E-61 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 SMALA_RS22795 1e1b1e97a5a794ae326e9407038d204e 384 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 36 45 - T 29-03-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SMALA_RS22795 1e1b1e97a5a794ae326e9407038d204e 384 Pfam PF00842 Alanine racemase, C-terminal domain 249 375 9.2E-42 T 29-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SMALA_RS22795 1e1b1e97a5a794ae326e9407038d204e 384 SUPERFAMILY SSF50621 242 378 2.41E-46 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 SMALA_RS08475 2594f16d49ab393c8cd91f7585504189 351 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 35 211 3.3E-43 T 29-03-2018 IPR004302 Cellulose/chitin-binding protein, N-terminal SMALA_RS08475 2594f16d49ab393c8cd91f7585504189 351 SUPERFAMILY SSF81296 35 215 1.01E-50 T 29-03-2018 IPR014756 Immunoglobulin E-set SMALA_RS08475 2594f16d49ab393c8cd91f7585504189 351 Gene3D G3DSA:2.70.50.50 35 214 3.4E-63 T 29-03-2018 SMALA_RS22590 428ecdee5ac32023364437b46d27eea3 107 Gene3D G3DSA:2.30.30.30 1 96 2.0E-33 T 29-03-2018 IPR014722 Ribosomal protein L2 domain 2 SMALA_RS22590 428ecdee5ac32023364437b46d27eea3 107 SUPERFAMILY SSF50104 1 105 2.22E-30 T 29-03-2018 IPR008991 Translation protein SH3-like domain SMALA_RS22590 428ecdee5ac32023364437b46d27eea3 107 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 1 107 9.1E-36 T 29-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS22590 428ecdee5ac32023364437b46d27eea3 107 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 38 107 7.1E-24 T 29-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS22590 428ecdee5ac32023364437b46d27eea3 107 SMART SM00739 2 29 2.1E-5 T 29-03-2018 IPR005824 KOW SMALA_RS22590 428ecdee5ac32023364437b46d27eea3 107 ProSitePatterns PS01108 Ribosomal protein L24 signature. 6 23 - T 29-03-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS22590 428ecdee5ac32023364437b46d27eea3 107 Pfam PF00467 KOW motif 5 36 2.5E-7 T 29-03-2018 IPR005824 KOW SMALA_RS22590 428ecdee5ac32023364437b46d27eea3 107 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 1 101 21.528 T 29-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS37965 fc4359a31c0b96955efa552454e7e0ad 340 SUPERFAMILY SSF51735 4 156 6.56E-44 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS37965 fc4359a31c0b96955efa552454e7e0ad 340 SUPERFAMILY SSF55347 131 300 5.23E-29 T 29-03-2018 SMALA_RS37965 fc4359a31c0b96955efa552454e7e0ad 340 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 7 125 1.6E-16 T 29-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 SMALA_RS37965 fc4359a31c0b96955efa552454e7e0ad 340 Gene3D G3DSA:3.40.50.720 1 144 6.3E-37 T 29-03-2018 SMALA_RS37965 fc4359a31c0b96955efa552454e7e0ad 340 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 139 234 2.3E-5 T 29-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 SMALA_RS37965 fc4359a31c0b96955efa552454e7e0ad 340 Gene3D G3DSA:3.30.360.10 145 327 1.0E-37 T 29-03-2018 SMALA_RS33180 52e5026cb20bcad0c00453271126e121 345 SUPERFAMILY SSF100950 81 326 1.78E-55 T 29-03-2018 SMALA_RS33180 52e5026cb20bcad0c00453271126e121 345 Gene3D G3DSA:3.40.50.1360 68 327 1.7E-39 T 29-03-2018 SMALA_RS33180 52e5026cb20bcad0c00453271126e121 345 Gene3D G3DSA:1.10.10.60 19 67 1.3E-7 T 29-03-2018 SMALA_RS33180 52e5026cb20bcad0c00453271126e121 345 Pfam PF04198 Putative sugar-binding domain 77 327 4.2E-67 T 29-03-2018 IPR007324 Sugar-binding domain, putative GO:0030246 SMALA_RS15305 e5b1f055bb4bf1258a5067b30899f53d 773 SMART SM01008 43 149 2.0E-45 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMALA_RS15305 e5b1f055bb4bf1258a5067b30899f53d 773 Gene3D G3DSA:3.90.1170.50 27 149 3.0E-34 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMALA_RS15305 e5b1f055bb4bf1258a5067b30899f53d 773 SUPERFAMILY SSF56003 150 766 1.05E-119 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMALA_RS15305 e5b1f055bb4bf1258a5067b30899f53d 773 Gene3D G3DSA:3.30.365.10 280 430 6.2E-40 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMALA_RS15305 e5b1f055bb4bf1258a5067b30899f53d 773 Gene3D G3DSA:3.30.365.10 178 279 7.5E-21 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMALA_RS15305 e5b1f055bb4bf1258a5067b30899f53d 773 Gene3D G3DSA:3.30.365.10 473 600 1.7E-19 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMALA_RS15305 e5b1f055bb4bf1258a5067b30899f53d 773 Gene3D G3DSA:3.30.365.10 601 770 1.6E-33 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMALA_RS15305 e5b1f055bb4bf1258a5067b30899f53d 773 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 185 712 1.2E-109 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMALA_RS15305 e5b1f055bb4bf1258a5067b30899f53d 773 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 44 148 2.1E-29 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMALA_RS15305 e5b1f055bb4bf1258a5067b30899f53d 773 SUPERFAMILY SSF54665 24 150 1.44E-39 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMALA_RS00555 7c036521f9028f0cdcff793c567e4b67 321 SUPERFAMILY SSF50129 2 150 4.41E-29 T 29-03-2018 IPR011032 GroES-like SMALA_RS00555 7c036521f9028f0cdcff793c567e4b67 321 Gene3D G3DSA:3.90.180.10 247 321 0.04 T 29-03-2018 SMALA_RS00555 7c036521f9028f0cdcff793c567e4b67 321 Pfam PF13602 Zinc-binding dehydrogenase 185 319 1.6E-16 T 29-03-2018 SMALA_RS00555 7c036521f9028f0cdcff793c567e4b67 321 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 89 1.0E-7 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS00555 7c036521f9028f0cdcff793c567e4b67 321 SMART SM00829 10 319 2.3E-11 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS00555 7c036521f9028f0cdcff793c567e4b67 321 Gene3D G3DSA:3.90.180.10 1 143 1.1E-34 T 29-03-2018 SMALA_RS00555 7c036521f9028f0cdcff793c567e4b67 321 Gene3D G3DSA:3.40.50.720 144 246 1.2E-16 T 29-03-2018 SMALA_RS00555 7c036521f9028f0cdcff793c567e4b67 321 SUPERFAMILY SSF51735 114 289 8.55E-26 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS42895 cac5e3fe4f5a46004f1c6a1743de3249 328 SUPERFAMILY SSF52317 5 196 3.93E-51 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS42895 cac5e3fe4f5a46004f1c6a1743de3249 328 Pfam PF12833 Helix-turn-helix domain 237 315 1.6E-21 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS42895 cac5e3fe4f5a46004f1c6a1743de3249 328 Gene3D G3DSA:1.10.10.60 272 319 1.0E-11 T 29-03-2018 SMALA_RS42895 cac5e3fe4f5a46004f1c6a1743de3249 328 Pfam PF01965 DJ-1/PfpI family 5 176 1.3E-24 T 29-03-2018 IPR002818 DJ-1/PfpI SMALA_RS42895 cac5e3fe4f5a46004f1c6a1743de3249 328 SMART SM00342 231 314 8.3E-25 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS42895 cac5e3fe4f5a46004f1c6a1743de3249 328 Gene3D G3DSA:1.10.10.60 232 271 5.9E-11 T 29-03-2018 SMALA_RS42895 cac5e3fe4f5a46004f1c6a1743de3249 328 Gene3D G3DSA:3.40.50.880 2 231 1.9E-71 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS42895 cac5e3fe4f5a46004f1c6a1743de3249 328 SUPERFAMILY SSF46689 267 317 6.27E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS42895 cac5e3fe4f5a46004f1c6a1743de3249 328 SUPERFAMILY SSF46689 216 264 3.81E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS31195 6b84e5d301f2b753d8228b58e266f253 287 Pfam PF13714 Phosphoenolpyruvate phosphomutase 19 244 9.2E-33 T 29-03-2018 SMALA_RS31195 6b84e5d301f2b753d8228b58e266f253 287 Gene3D G3DSA:3.20.20.60 2 272 2.3E-52 T 29-03-2018 SMALA_RS31195 6b84e5d301f2b753d8228b58e266f253 287 SUPERFAMILY SSF51621 4 249 2.92E-57 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SMALA_RS00455 7207310031f676d23e3fdb4af54e64d1 281 SUPERFAMILY SSF51197 206 267 1.36E-6 T 29-03-2018 SMALA_RS00455 7207310031f676d23e3fdb4af54e64d1 281 Pfam PF13640 2OG-Fe(II) oxygenase superfamily 161 269 2.3E-7 T 29-03-2018 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 SMALA_RS00455 7207310031f676d23e3fdb4af54e64d1 281 Gene3D G3DSA:2.60.120.620 97 277 1.8E-18 T 29-03-2018 SMALA_RS35845 0b0069507e05df07d0118fe8f1fc8cbf 742 SUPERFAMILY SSF52242 574 737 2.35E-59 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 SMALA_RS35845 0b0069507e05df07d0118fe8f1fc8cbf 742 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 608 735 5.1E-62 T 29-03-2018 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMALA_RS35845 0b0069507e05df07d0118fe8f1fc8cbf 742 Gene3D G3DSA:3.20.20.240 50 571 3.0E-244 T 29-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMALA_RS35845 0b0069507e05df07d0118fe8f1fc8cbf 742 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 50 576 1.9E-276 T 29-03-2018 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMALA_RS35845 0b0069507e05df07d0118fe8f1fc8cbf 742 SUPERFAMILY SSF51703 33 571 1.73E-222 T 29-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMALA_RS35845 0b0069507e05df07d0118fe8f1fc8cbf 742 Gene3D G3DSA:3.40.50.280 593 740 8.0E-41 T 29-03-2018 SMALA_RS35845 0b0069507e05df07d0118fe8f1fc8cbf 742 Pfam PF02310 B12 binding domain 611 721 6.4E-15 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 SMALA_RS35845 0b0069507e05df07d0118fe8f1fc8cbf 742 ProSitePatterns PS00544 Methylmalonyl-CoA mutase signature. 393 418 - T 29-03-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMALA_RS35845 0b0069507e05df07d0118fe8f1fc8cbf 742 Pfam PF01642 Methylmalonyl-CoA mutase 52 569 3.4E-234 T 29-03-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMALA_RS32615 8e2efb57ee4cb0baad0ac04df549c04f 379 SUPERFAMILY SSF53335 92 208 2.62E-24 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS32615 8e2efb57ee4cb0baad0ac04df549c04f 379 Gene3D G3DSA:3.40.50.150 8 260 5.1E-28 T 29-03-2018 SMALA_RS32615 8e2efb57ee4cb0baad0ac04df549c04f 379 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 92 225 2.1E-17 T 29-03-2018 SMALA_RS07380 99e586bd92d7e9a21180cddecce63a91 345 Gene3D G3DSA:1.10.3470.10 48 338 2.8E-30 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SMALA_RS07380 99e586bd92d7e9a21180cddecce63a91 345 Pfam PF02653 Branched-chain amino acid transport system / permease component 59 333 2.2E-40 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 SMALA_RS35035 776f93b642b90af19607ec6f90e7a1c4 401 Gene3D G3DSA:2.120.10.10 30 401 4.7E-59 T 29-03-2018 SMALA_RS35035 776f93b642b90af19607ec6f90e7a1c4 401 Pfam PF13088 BNR repeat-like domain 48 379 6.8E-67 T 29-03-2018 IPR011040 Sialidases KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 SMALA_RS35035 776f93b642b90af19607ec6f90e7a1c4 401 SUPERFAMILY SSF50939 34 277 5.89E-58 T 29-03-2018 IPR011040 Sialidases KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 SMALA_RS35035 776f93b642b90af19607ec6f90e7a1c4 401 SUPERFAMILY SSF50939 317 398 5.89E-58 T 29-03-2018 IPR011040 Sialidases KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 SMALA_RS00125 c0b82c1927ce3122a00fbc561a40ea70 1272 SUPERFAMILY SSF52540 306 467 2.01E-6 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS00125 c0b82c1927ce3122a00fbc561a40ea70 1272 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 1134 1148 - T 29-03-2018 IPR019775 WD40 repeat, conserved site SMALA_RS00125 c0b82c1927ce3122a00fbc561a40ea70 1272 SMART SM00320 1150 1191 0.0038 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 SMALA_RS00125 c0b82c1927ce3122a00fbc561a40ea70 1272 SMART SM00320 1194 1234 0.21 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 SMALA_RS00125 c0b82c1927ce3122a00fbc561a40ea70 1272 SMART SM00320 1061 1102 39.0 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 SMALA_RS00125 c0b82c1927ce3122a00fbc561a40ea70 1272 SMART SM00320 1014 1054 6.2E-5 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 SMALA_RS00125 c0b82c1927ce3122a00fbc561a40ea70 1272 SMART SM00320 920 961 2.5 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 SMALA_RS00125 c0b82c1927ce3122a00fbc561a40ea70 1272 SMART SM00320 834 874 2.7 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 SMALA_RS00125 c0b82c1927ce3122a00fbc561a40ea70 1272 SMART SM00320 1104 1147 150.0 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 SMALA_RS00125 c0b82c1927ce3122a00fbc561a40ea70 1272 SMART SM00320 877 917 9.9 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 SMALA_RS00125 c0b82c1927ce3122a00fbc561a40ea70 1272 SMART SM00320 790 831 21.0 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 SMALA_RS00125 c0b82c1927ce3122a00fbc561a40ea70 1272 Gene3D G3DSA:3.40.50.300 306 474 1.0E-6 T 29-03-2018 SMALA_RS00125 c0b82c1927ce3122a00fbc561a40ea70 1272 Pfam PF00656 Caspase domain 35 153 3.6E-5 T 29-03-2018 SMALA_RS00125 c0b82c1927ce3122a00fbc561a40ea70 1272 Gene3D G3DSA:2.80.10.50 1052 1110 5.3E-5 T 29-03-2018 SMALA_RS00125 c0b82c1927ce3122a00fbc561a40ea70 1272 Gene3D G3DSA:3.40.50.1460 3 243 3.1E-20 T 29-03-2018 SMALA_RS00125 c0b82c1927ce3122a00fbc561a40ea70 1272 Gene3D G3DSA:2.120.10.30 980 1051 4.3E-12 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like SMALA_RS00125 c0b82c1927ce3122a00fbc561a40ea70 1272 Gene3D G3DSA:2.140.10.10 1111 1240 7.8E-22 T 29-03-2018 SMALA_RS00125 c0b82c1927ce3122a00fbc561a40ea70 1272 SUPERFAMILY SSF52129 27 157 2.58E-7 T 29-03-2018 IPR029030 Caspase-like domain SMALA_RS00125 c0b82c1927ce3122a00fbc561a40ea70 1272 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 1089 1103 - T 29-03-2018 IPR019775 WD40 repeat, conserved site SMALA_RS00125 c0b82c1927ce3122a00fbc561a40ea70 1272 Gene3D G3DSA:2.130.10.10 728 979 1.9E-25 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMALA_RS00125 c0b82c1927ce3122a00fbc561a40ea70 1272 SUPERFAMILY SSF50978 1070 1239 3.48E-23 T 29-03-2018 IPR017986 WD40-repeat-containing domain GO:0005515 SMALA_RS00125 c0b82c1927ce3122a00fbc561a40ea70 1272 SUPERFAMILY SSF50978 806 1125 1.47E-42 T 29-03-2018 IPR017986 WD40-repeat-containing domain GO:0005515 SMALA_RS27760 1dcf37714e59f7a703de432889b2bbf7 318 PRINTS PR00733 Glycosyl hydrolase family 6 signature 286 300 2.5E-40 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMALA_RS27760 1dcf37714e59f7a703de432889b2bbf7 318 PRINTS PR00733 Glycosyl hydrolase family 6 signature 55 74 2.5E-40 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMALA_RS27760 1dcf37714e59f7a703de432889b2bbf7 318 PRINTS PR00733 Glycosyl hydrolase family 6 signature 262 282 2.5E-40 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMALA_RS27760 1dcf37714e59f7a703de432889b2bbf7 318 PRINTS PR00733 Glycosyl hydrolase family 6 signature 246 259 2.5E-40 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMALA_RS27760 1dcf37714e59f7a703de432889b2bbf7 318 PRINTS PR00733 Glycosyl hydrolase family 6 signature 182 195 2.5E-40 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMALA_RS27760 1dcf37714e59f7a703de432889b2bbf7 318 PRINTS PR00733 Glycosyl hydrolase family 6 signature 126 141 2.5E-40 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMALA_RS27760 1dcf37714e59f7a703de432889b2bbf7 318 PRINTS PR00733 Glycosyl hydrolase family 6 signature 98 111 2.5E-40 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMALA_RS27760 1dcf37714e59f7a703de432889b2bbf7 318 PRINTS PR00733 Glycosyl hydrolase family 6 signature 213 223 2.5E-40 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMALA_RS27760 1dcf37714e59f7a703de432889b2bbf7 318 ProSitePatterns PS00656 Glycosyl hydrolases family 6 signature 2. 143 152 - T 29-03-2018 IPR001524 Glycoside hydrolase, family 6, conserved site GO:0004553|GO:0005975 SMALA_RS27760 1dcf37714e59f7a703de432889b2bbf7 318 Pfam PF01341 Glycosyl hydrolases family 6 57 302 5.7E-64 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMALA_RS27760 1dcf37714e59f7a703de432889b2bbf7 318 PIRSF PIRSF001100 6 318 1.1E-86 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMALA_RS27760 1dcf37714e59f7a703de432889b2bbf7 318 Gene3D G3DSA:3.20.20.40 33 318 1.4E-86 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMALA_RS27760 1dcf37714e59f7a703de432889b2bbf7 318 SUPERFAMILY SSF51989 35 317 5.89E-86 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMALA_RS27760 1dcf37714e59f7a703de432889b2bbf7 318 ProSitePatterns PS00655 Glycosyl hydrolases family 6 signature 1. 103 119 - T 29-03-2018 IPR001524 Glycoside hydrolase, family 6, conserved site GO:0004553|GO:0005975 SMALA_RS29485 1663beaaa670dc556ed718ac012c9fda 1324 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 486 897 4.3E-132 T 29-03-2018 IPR010071 Amino acid adenylation domain SMALA_RS29485 1663beaaa670dc556ed718ac012c9fda 1324 Gene3D G3DSA:2.30.38.10 785 866 4.0E-22 T 29-03-2018 SMALA_RS29485 1663beaaa670dc556ed718ac012c9fda 1324 SUPERFAMILY SSF56801 427 993 2.22E-161 T 29-03-2018 SMALA_RS29485 1663beaaa670dc556ed718ac012c9fda 1324 SUPERFAMILY SSF52777 11 185 1.89E-41 T 29-03-2018 SMALA_RS29485 1663beaaa670dc556ed718ac012c9fda 1324 Gene3D G3DSA:3.30.300.30 868 986 1.3E-38 T 29-03-2018 SMALA_RS29485 1663beaaa670dc556ed718ac012c9fda 1324 SUPERFAMILY SSF53474 1049 1309 4.02E-59 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS29485 1663beaaa670dc556ed718ac012c9fda 1324 SMART SM00824 Thioesterase 1071 1305 3.4E-6 T 29-03-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 SMALA_RS29485 1663beaaa670dc556ed718ac012c9fda 1324 Pfam PF00501 AMP-binding enzyme 465 873 7.8E-99 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS29485 1663beaaa670dc556ed718ac012c9fda 1324 Pfam PF00550 Phosphopantetheine attachment site 984 1046 2.6E-16 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS29485 1663beaaa670dc556ed718ac012c9fda 1324 Gene3D G3DSA:1.10.1200.10 987 1052 3.8E-24 T 29-03-2018 SMALA_RS29485 1663beaaa670dc556ed718ac012c9fda 1324 Pfam PF00975 Thioesterase domain 1069 1294 8.5E-28 T 29-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 SMALA_RS29485 1663beaaa670dc556ed718ac012c9fda 1324 Pfam PF13193 AMP-binding enzyme C-terminal domain 881 956 1.5E-13 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS29485 1663beaaa670dc556ed718ac012c9fda 1324 Gene3D G3DSA:3.30.559.10 1 193 2.0E-34 T 29-03-2018 SMALA_RS29485 1663beaaa670dc556ed718ac012c9fda 1324 ProSitePatterns PS00455 Putative AMP-binding domain signature. 608 619 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS29485 1663beaaa670dc556ed718ac012c9fda 1324 Gene3D G3DSA:3.40.50.1820 1053 1310 8.8E-28 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS29485 1663beaaa670dc556ed718ac012c9fda 1324 Gene3D G3DSA:3.40.50.980 457 612 9.7E-48 T 29-03-2018 SMALA_RS29485 1663beaaa670dc556ed718ac012c9fda 1324 Pfam PF00668 Condensation domain 8 445 6.3E-73 T 29-03-2018 IPR001242 Condensation domain SMALA_RS29485 1663beaaa670dc556ed718ac012c9fda 1324 SUPERFAMILY SSF47336 974 1047 1.57E-20 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS29485 1663beaaa670dc556ed718ac012c9fda 1324 Gene3D G3DSA:3.40.50.980 613 771 3.2E-42 T 29-03-2018 SMALA_RS29485 1663beaaa670dc556ed718ac012c9fda 1324 SMART SM00823 Phosphopantetheine attachment site 981 1050 2.5E-6 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS29485 1663beaaa670dc556ed718ac012c9fda 1324 SUPERFAMILY SSF52777 191 429 2.56E-40 T 29-03-2018 SMALA_RS39200 7cad42519607efe67d900f432c6263fd 276 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 98 273 5.0E-11 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 SMALA_RS39200 7cad42519607efe67d900f432c6263fd 276 SUPERFAMILY SSF56529 19 273 2.44E-73 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 SMALA_RS39200 7cad42519607efe67d900f432c6263fd 276 Gene3D G3DSA:3.90.850.10 14 276 1.1E-49 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 SMALA_RS01235 a888e2c710d55d1033851f0288ebd6f2 818 Gene3D G3DSA:1.20.1050.60 409 504 1.9E-18 T 29-03-2018 SMALA_RS01235 a888e2c710d55d1033851f0288ebd6f2 818 Gene3D G3DSA:1.20.1610.10 515 668 3.2E-47 T 29-03-2018 SMALA_RS01235 a888e2c710d55d1033851f0288ebd6f2 818 Pfam PF07971 Glycosyl hydrolase family 92 299 802 9.1E-156 T 29-03-2018 IPR012939 Glycosyl hydrolase family 92 SMALA_RS01235 a888e2c710d55d1033851f0288ebd6f2 818 TIGRFAM TIGR01180 aman2_put: putative alpha-1,2-mannosidase 38 806 1.9E-155 T 29-03-2018 IPR005887 Alpha-1,2-mannosidase, putative SMALA_RS01235 a888e2c710d55d1033851f0288ebd6f2 818 Gene3D G3DSA:3.30.2080.10 669 815 1.1E-53 T 29-03-2018 SMALA_RS01235 a888e2c710d55d1033851f0288ebd6f2 818 Gene3D G3DSA:2.70.98.10 49 384 2.1E-91 T 29-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 SMALA_RS01235 a888e2c710d55d1033851f0288ebd6f2 818 SUPERFAMILY SSF48208 325 786 2.55E-16 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 SMALA_RS06745 246b5177a475c35d6845386fcdd2fcf4 427 SUPERFAMILY SSF47413 5 58 5.63E-9 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS06745 246b5177a475c35d6845386fcdd2fcf4 427 Gene3D G3DSA:1.25.40.10 63 422 1.0E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS06745 246b5177a475c35d6845386fcdd2fcf4 427 SMART SM00530 9 64 2.7E-8 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS06745 246b5177a475c35d6845386fcdd2fcf4 427 Pfam PF13560 Helix-turn-helix domain 6 67 1.7E-11 T 29-03-2018 SMALA_RS06745 246b5177a475c35d6845386fcdd2fcf4 427 Gene3D G3DSA:1.10.260.40 1 62 3.9E-13 T 29-03-2018 SMALA_RS06745 246b5177a475c35d6845386fcdd2fcf4 427 SUPERFAMILY SSF48452 275 380 3.25E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS23735 6aec634b8e658323133d20ca4f219312 501 Pfam PF00999 Sodium/hydrogen exchanger family 20 389 3.3E-49 T 29-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 SMALA_RS23735 6aec634b8e658323133d20ca4f219312 501 Gene3D G3DSA:3.30.70.1450 412 488 2.0E-13 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 SMALA_RS23735 6aec634b8e658323133d20ca4f219312 501 SUPERFAMILY SSF116726 413 481 2.88E-11 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 SMALA_RS23735 6aec634b8e658323133d20ca4f219312 501 Pfam PF02080 TrkA-C domain 418 473 7.0E-10 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 SMALA_RS08590 e150ddf59515c5894ad009f30f743ab9 150 Pfam PF00741 Gas vesicle protein 19 56 1.7E-12 T 29-03-2018 IPR000638 Gas vesicle protein GvpA GO:0005198|GO:0012506 SMALA_RS08590 e150ddf59515c5894ad009f30f743ab9 150 ProSitePatterns PS00234 Gas vesicles protein GVPa signature 1. 19 33 - T 29-03-2018 IPR018493 Gas vesicle protein GvpA, conserved site GO:0005198|GO:0012506 SMALA_RS08590 e150ddf59515c5894ad009f30f743ab9 150 ProSitePatterns PS00669 Gas vesicles protein GVPa signature 2. 52 65 - T 29-03-2018 IPR018493 Gas vesicle protein GvpA, conserved site GO:0005198|GO:0012506 SMALA_RS08590 e150ddf59515c5894ad009f30f743ab9 150 Hamap MF_00576 Gas vesicle structural protein [gvpA]. 7 95 28.298 T 29-03-2018 IPR000638 Gas vesicle protein GvpA GO:0005198|GO:0012506 SMALA_RS39545 915ce05b1020b5daa5d6d4d5446639ac 525 SUPERFAMILY SSF51338 4 57 3.09E-19 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS39545 915ce05b1020b5daa5d6d4d5446639ac 525 SUPERFAMILY SSF51338 480 519 3.09E-19 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS39545 915ce05b1020b5daa5d6d4d5446639ac 525 Pfam PF07969 Amidohydrolase family 45 518 6.7E-80 T 29-03-2018 IPR013108 Amidohydrolase 3 SMALA_RS39545 915ce05b1020b5daa5d6d4d5446639ac 525 SUPERFAMILY SSF51556 172 481 1.28E-31 T 29-03-2018 IPR032466 Metal-dependent hydrolase SMALA_RS39545 915ce05b1020b5daa5d6d4d5446639ac 525 SUPERFAMILY SSF51556 56 114 1.28E-31 T 29-03-2018 IPR032466 Metal-dependent hydrolase SMALA_RS39545 915ce05b1020b5daa5d6d4d5446639ac 525 Gene3D G3DSA:3.20.20.140 67 478 1.1E-50 T 29-03-2018 SMALA_RS39545 915ce05b1020b5daa5d6d4d5446639ac 525 Gene3D G3DSA:2.30.40.10 2 66 5.4E-18 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS19700 45f6ecfea03954cc4b6d5cdd06e8117f 105 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 16 68 3.0E-25 T 29-03-2018 IPR002696 Putative membrane protein insertion efficiency factor SMALA_RS19700 45f6ecfea03954cc4b6d5cdd06e8117f 105 SMART SM01234 1 68 1.1E-40 T 29-03-2018 IPR002696 Putative membrane protein insertion efficiency factor SMALA_RS19700 45f6ecfea03954cc4b6d5cdd06e8117f 105 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 5 73 2.6E-25 T 29-03-2018 IPR002696 Putative membrane protein insertion efficiency factor SMALA_RS19700 45f6ecfea03954cc4b6d5cdd06e8117f 105 Pfam PF01809 Haemolytic domain 5 68 2.5E-27 T 29-03-2018 IPR002696 Putative membrane protein insertion efficiency factor SMALA_RS19700 45f6ecfea03954cc4b6d5cdd06e8117f 105 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 1 69 23.466 T 29-03-2018 IPR002696 Putative membrane protein insertion efficiency factor SMALA_RS28365 eb3ccd4c5ff1367e1900462c147d311d 309 Pfam PF01569 PAP2 superfamily 207 284 2.8E-10 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMALA_RS28365 eb3ccd4c5ff1367e1900462c147d311d 309 SUPERFAMILY SSF48317 86 290 3.01E-23 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMALA_RS28365 eb3ccd4c5ff1367e1900462c147d311d 309 Gene3D G3DSA:1.20.144.10 94 303 1.4E-16 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMALA_RS38205 77e50db7aaf67ac5a05d767448b4ae33 1101 Pfam PF13193 AMP-binding enzyme C-terminal domain 666 739 1.2E-13 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS38205 77e50db7aaf67ac5a05d767448b4ae33 1101 Gene3D G3DSA:3.40.50.980 245 402 1.2E-45 T 29-03-2018 SMALA_RS38205 77e50db7aaf67ac5a05d767448b4ae33 1101 SUPERFAMILY SSF53474 844 1091 1.47E-31 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS38205 77e50db7aaf67ac5a05d767448b4ae33 1101 Gene3D G3DSA:3.40.50.1820 841 1091 5.5E-21 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS38205 77e50db7aaf67ac5a05d767448b4ae33 1101 Gene3D G3DSA:1.10.1200.10 773 840 6.0E-18 T 29-03-2018 SMALA_RS38205 77e50db7aaf67ac5a05d767448b4ae33 1101 Gene3D G3DSA:3.30.300.30 653 772 2.7E-37 T 29-03-2018 SMALA_RS38205 77e50db7aaf67ac5a05d767448b4ae33 1101 SUPERFAMILY SSF47336 759 829 6.54E-15 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS38205 77e50db7aaf67ac5a05d767448b4ae33 1101 SUPERFAMILY SSF52777 17 220 4.45E-12 T 29-03-2018 SMALA_RS38205 77e50db7aaf67ac5a05d767448b4ae33 1101 Gene3D G3DSA:3.40.50.980 403 552 3.0E-32 T 29-03-2018 SMALA_RS38205 77e50db7aaf67ac5a05d767448b4ae33 1101 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 273 682 1.1E-111 T 29-03-2018 IPR010071 Amino acid adenylation domain SMALA_RS38205 77e50db7aaf67ac5a05d767448b4ae33 1101 Gene3D G3DSA:2.30.38.10 568 648 1.7E-22 T 29-03-2018 SMALA_RS38205 77e50db7aaf67ac5a05d767448b4ae33 1101 Pfam PF00975 Thioesterase domain 858 1081 9.9E-17 T 29-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 SMALA_RS38205 77e50db7aaf67ac5a05d767448b4ae33 1101 Pfam PF00501 AMP-binding enzyme 252 658 1.0E-90 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS38205 77e50db7aaf67ac5a05d767448b4ae33 1101 Pfam PF00550 Phosphopantetheine attachment site 767 826 8.9E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS38205 77e50db7aaf67ac5a05d767448b4ae33 1101 SUPERFAMILY SSF56801 229 779 2.88E-148 T 29-03-2018 SMALA_RS38205 77e50db7aaf67ac5a05d767448b4ae33 1101 ProSitePatterns PS00455 Putative AMP-binding domain signature. 398 409 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS40100 4863667ef3ab020461c973d922823016 290 SUPERFAMILY SSF48179 153 281 1.59E-30 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMALA_RS40100 4863667ef3ab020461c973d922823016 290 PIRSF PIRSF000103 1 284 5.1E-53 T 29-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 SMALA_RS40100 4863667ef3ab020461c973d922823016 290 Gene3D G3DSA:3.40.50.720 1 162 2.8E-24 T 29-03-2018 SMALA_RS40100 4863667ef3ab020461c973d922823016 290 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 155 274 5.7E-26 T 29-03-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 SMALA_RS40100 4863667ef3ab020461c973d922823016 290 SUPERFAMILY SSF51735 1 153 4.29E-29 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS40100 4863667ef3ab020461c973d922823016 290 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 1 152 4.1E-30 T 29-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 SMALA_RS40100 4863667ef3ab020461c973d922823016 290 Gene3D G3DSA:1.10.1040.10 163 283 6.2E-29 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMALA_RS26160 598045612b58b97ac2de2830c848c959 335 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 70 324 1.0E-43 T 29-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 SMALA_RS26160 598045612b58b97ac2de2830c848c959 335 Pfam PF03193 RsgA GTPase 95 270 4.7E-45 T 29-03-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 SMALA_RS26160 598045612b58b97ac2de2830c848c959 335 Gene3D G3DSA:1.10.40.50 271 335 1.9E-19 T 29-03-2018 SMALA_RS26160 598045612b58b97ac2de2830c848c959 335 SUPERFAMILY SSF52540 113 330 1.95E-41 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS26160 598045612b58b97ac2de2830c848c959 335 Gene3D G3DSA:3.40.50.300 112 270 3.9E-21 T 29-03-2018 SMALA_RS26160 598045612b58b97ac2de2830c848c959 335 Hamap MF_01820 Putative ribosome biogenesis GTPase RsgA [rsgA]. 36 333 27.124 T 29-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 SMALA_RS40340 6c365a52c94000bcddb62d6e98223ffd 563 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 6 174 8.3E-48 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 SMALA_RS40340 6c365a52c94000bcddb62d6e98223ffd 563 Gene3D G3DSA:3.40.50.1220 194 354 2.5E-36 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain SMALA_RS40340 6c365a52c94000bcddb62d6e98223ffd 563 SUPERFAMILY SSF52518 374 554 4.76E-51 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold SMALA_RS40340 6c365a52c94000bcddb62d6e98223ffd 563 Gene3D G3DSA:3.40.50.970 1 193 2.5E-47 T 29-03-2018 SMALA_RS40340 6c365a52c94000bcddb62d6e98223ffd 563 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 434 453 - T 29-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 SMALA_RS40340 6c365a52c94000bcddb62d6e98223ffd 563 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 398 544 1.2E-35 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 SMALA_RS40340 6c365a52c94000bcddb62d6e98223ffd 563 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 199 332 5.7E-31 T 29-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 SMALA_RS40340 6c365a52c94000bcddb62d6e98223ffd 563 SUPERFAMILY SSF52518 4 180 1.49E-46 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold SMALA_RS40340 6c365a52c94000bcddb62d6e98223ffd 563 Gene3D G3DSA:3.40.50.970 355 562 1.3E-37 T 29-03-2018 SMALA_RS40340 6c365a52c94000bcddb62d6e98223ffd 563 SUPERFAMILY SSF52467 157 363 7.51E-37 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain SMALA_RS19710 49e6ffe483fb40513a49a7cb8ebfd1ff 45 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 3 45 2.8E-20 T 29-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS19710 49e6ffe483fb40513a49a7cb8ebfd1ff 45 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 2 45 15.729 T 29-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS19710 49e6ffe483fb40513a49a7cb8ebfd1ff 45 Pfam PF00468 Ribosomal protein L34 3 45 1.9E-20 T 29-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS19710 49e6ffe483fb40513a49a7cb8ebfd1ff 45 ProSitePatterns PS00784 Ribosomal protein L34 signature. 3 22 - T 29-03-2018 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS19710 49e6ffe483fb40513a49a7cb8ebfd1ff 45 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 3 40 3.0E-13 T 29-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS37980 5e5c2aff8c83d147ef332769bbf1af2d 392 SUPERFAMILY SSF51197 78 360 6.41E-49 T 29-03-2018 SMALA_RS37980 5e5c2aff8c83d147ef332769bbf1af2d 392 Gene3D G3DSA:2.60.120.620 56 307 1.3E-27 T 29-03-2018 SMALA_RS37980 5e5c2aff8c83d147ef332769bbf1af2d 392 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 78 288 4.4E-36 T 29-03-2018 IPR008775 Phytanoyl-CoA dioxygenase SMALA_RS02420 01b3aab1f0d0dc746ff2a5dbe896aec5 154 Gene3D G3DSA:3.30.530.20 2 154 3.3E-26 T 29-03-2018 IPR023393 START-like domain SMALA_RS02420 01b3aab1f0d0dc746ff2a5dbe896aec5 154 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 11 151 2.3E-18 T 29-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 SMALA_RS02420 01b3aab1f0d0dc746ff2a5dbe896aec5 154 SUPERFAMILY SSF55961 3 152 2.96E-32 T 29-03-2018 SMALA_RS03010 1d50e3acc7393141c8add9132645ba9e 54 ProSitePatterns PS00582 Ribosomal protein L33 signature. 22 41 - T 29-03-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS03010 1d50e3acc7393141c8add9132645ba9e 54 SUPERFAMILY SSF57829 4 54 2.87E-16 T 29-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 SMALA_RS03010 1d50e3acc7393141c8add9132645ba9e 54 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 2 54 13.753 T 29-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS03010 1d50e3acc7393141c8add9132645ba9e 54 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 1 54 1.3E-20 T 29-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS03010 1d50e3acc7393141c8add9132645ba9e 54 Pfam PF00471 Ribosomal protein L33 9 54 7.7E-15 T 29-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS24260 46bab160201efaf478dabfa68f477315 240 Gene3D G3DSA:1.10.10.10 1 87 1.4E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS24260 46bab160201efaf478dabfa68f477315 240 Pfam PF07729 FCD domain 100 220 1.3E-30 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS24260 46bab160201efaf478dabfa68f477315 240 Pfam PF00392 Bacterial regulatory proteins, gntR family 21 76 2.6E-21 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS24260 46bab160201efaf478dabfa68f477315 240 SUPERFAMILY SSF48008 97 227 1.7E-29 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS24260 46bab160201efaf478dabfa68f477315 240 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 50 66 1.0E-10 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS24260 46bab160201efaf478dabfa68f477315 240 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 36 50 1.0E-10 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS24260 46bab160201efaf478dabfa68f477315 240 SMART SM00345 17 76 7.1E-22 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS24260 46bab160201efaf478dabfa68f477315 240 SMART SM00895 100 221 8.0E-26 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS24260 46bab160201efaf478dabfa68f477315 240 SUPERFAMILY SSF46785 9 80 2.34E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS24260 46bab160201efaf478dabfa68f477315 240 Gene3D G3DSA:1.20.120.530 94 237 4.0E-33 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS19715 336d735ce577974ea99928631df3eeb7 609 Pfam PF00308 Bacterial dnaA protein 270 487 7.3E-104 T 29-03-2018 IPR013317 Chromosomal replication initiator protein DnaA SMALA_RS19715 336d735ce577974ea99928631df3eeb7 609 SUPERFAMILY SSF48295 513 608 1.15E-33 T 29-03-2018 IPR010921 Trp repressor/replication initiator GO:0043565 SMALA_RS19715 336d735ce577974ea99928631df3eeb7 609 Gene3D G3DSA:1.10.1750.10 513 609 1.8E-35 T 29-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 SMALA_RS19715 336d735ce577974ea99928631df3eeb7 609 ProSitePatterns PS01008 DnaA protein signature. 566 585 - T 29-03-2018 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 SMALA_RS19715 336d735ce577974ea99928631df3eeb7 609 Gene3D G3DSA:1.10.8.60 436 507 1.8E-26 T 29-03-2018 SMALA_RS19715 336d735ce577974ea99928631df3eeb7 609 SMART SM00760 516 585 1.9E-34 T 29-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 SMALA_RS19715 336d735ce577974ea99928631df3eeb7 609 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 335 349 5.2E-52 T 29-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like SMALA_RS19715 336d735ce577974ea99928631df3eeb7 609 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 367 381 5.2E-52 T 29-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like SMALA_RS19715 336d735ce577974ea99928631df3eeb7 609 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 303 323 5.2E-52 T 29-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like SMALA_RS19715 336d735ce577974ea99928631df3eeb7 609 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 401 428 5.2E-52 T 29-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like SMALA_RS19715 336d735ce577974ea99928631df3eeb7 609 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 566 585 5.2E-52 T 29-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like SMALA_RS19715 336d735ce577974ea99928631df3eeb7 609 Gene3D G3DSA:3.40.50.300 267 434 1.1E-23 T 29-03-2018 SMALA_RS19715 336d735ce577974ea99928631df3eeb7 609 SMART SM00382 302 430 2.2E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS19715 336d735ce577974ea99928631df3eeb7 609 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 9 607 33.253 T 29-03-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 SMALA_RS19715 336d735ce577974ea99928631df3eeb7 609 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 36 606 3.7E-154 T 29-03-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 SMALA_RS19715 336d735ce577974ea99928631df3eeb7 609 SUPERFAMILY SSF52540 269 481 9.0E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS19715 336d735ce577974ea99928631df3eeb7 609 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 519 585 3.8E-29 T 29-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 SMALA_RS10540 c77574218f1a7e5a57af8b140c7b96be 133 Gene3D G3DSA:3.40.50.2300 2 133 3.2E-10 T 29-03-2018 SMALA_RS10540 c77574218f1a7e5a57af8b140c7b96be 133 SUPERFAMILY SSF52172 6 129 1.99E-8 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS01450 553a09a8e5b5dc21d8f48e83e3a559e8 227 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 46 1.4E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS01450 553a09a8e5b5dc21d8f48e83e3a559e8 227 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 53 76 1.4E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS01450 553a09a8e5b5dc21d8f48e83e3a559e8 227 SUPERFAMILY SSF48498 97 202 6.67E-15 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS01450 553a09a8e5b5dc21d8f48e83e3a559e8 227 SUPERFAMILY SSF46689 23 96 3.21E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS01450 553a09a8e5b5dc21d8f48e83e3a559e8 227 Pfam PF00440 Bacterial regulatory proteins, tetR family 34 78 5.9E-14 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS01450 553a09a8e5b5dc21d8f48e83e3a559e8 227 Gene3D G3DSA:1.10.357.10 76 210 1.5E-15 T 29-03-2018 SMALA_RS01450 553a09a8e5b5dc21d8f48e83e3a559e8 227 Gene3D G3DSA:1.10.10.60 10 75 4.2E-16 T 29-03-2018 SMALA_RS02125 5ec22761f303a31c330c71dad7dd381c 309 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 258 300 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 SMALA_RS02125 5ec22761f303a31c330c71dad7dd381c 309 SUPERFAMILY SSF46689 210 255 7.17E-9 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS02125 5ec22761f303a31c330c71dad7dd381c 309 Pfam PF12833 Helix-turn-helix domain 227 305 2.0E-23 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS02125 5ec22761f303a31c330c71dad7dd381c 309 SMART SM00342 221 304 4.4E-29 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS02125 5ec22761f303a31c330c71dad7dd381c 309 Gene3D G3DSA:1.10.10.60 223 260 8.6E-13 T 29-03-2018 SMALA_RS02125 5ec22761f303a31c330c71dad7dd381c 309 Pfam PF01965 DJ-1/PfpI family 3 166 1.5E-18 T 29-03-2018 IPR002818 DJ-1/PfpI SMALA_RS02125 5ec22761f303a31c330c71dad7dd381c 309 SUPERFAMILY SSF52317 3 187 2.32E-43 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS02125 5ec22761f303a31c330c71dad7dd381c 309 Gene3D G3DSA:1.10.10.60 261 309 2.7E-12 T 29-03-2018 SMALA_RS02125 5ec22761f303a31c330c71dad7dd381c 309 Gene3D G3DSA:3.40.50.880 1 222 6.8E-59 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS02125 5ec22761f303a31c330c71dad7dd381c 309 SUPERFAMILY SSF46689 258 307 4.25E-10 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS31980 1c20e21a28e62363aea3d521d276e716 496 Gene3D G3DSA:1.10.390.10 308 459 3.9E-37 T 29-03-2018 SMALA_RS31980 1c20e21a28e62363aea3d521d276e716 496 SUPERFAMILY SSF55486 236 462 1.3E-49 T 29-03-2018 SMALA_RS31980 1c20e21a28e62363aea3d521d276e716 496 Gene3D G3DSA:2.60.40.1730 44 227 1.4E-41 T 29-03-2018 SMALA_RS31980 1c20e21a28e62363aea3d521d276e716 496 Pfam PF01433 Peptidase family M1 domain 311 455 2.7E-27 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMALA_RS31980 1c20e21a28e62363aea3d521d276e716 496 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 209 224 4.5E-11 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMALA_RS31980 1c20e21a28e62363aea3d521d276e716 496 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 162 177 4.5E-11 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMALA_RS31980 1c20e21a28e62363aea3d521d276e716 496 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 334 346 4.5E-11 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMALA_RS31980 1c20e21a28e62363aea3d521d276e716 496 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 315 330 4.5E-11 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMALA_RS31980 1c20e21a28e62363aea3d521d276e716 496 SUPERFAMILY SSF63737 33 225 2.22E-36 T 29-03-2018 SMALA_RS16780 e59922d3a7b317638ddd4bdaea19f69f 474 Gene3D G3DSA:3.90.1150.10 353 474 8.7E-22 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS16780 e59922d3a7b317638ddd4bdaea19f69f 474 Pfam PF00155 Aminotransferase class I and II 122 406 5.3E-16 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMALA_RS16780 e59922d3a7b317638ddd4bdaea19f69f 474 SMART SM00345 21 80 1.8E-15 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS16780 e59922d3a7b317638ddd4bdaea19f69f 474 SUPERFAMILY SSF53383 75 473 5.23E-74 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS16780 e59922d3a7b317638ddd4bdaea19f69f 474 Pfam PF00392 Bacterial regulatory proteins, gntR family 20 80 4.5E-17 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS16780 e59922d3a7b317638ddd4bdaea19f69f 474 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 54 70 4.5E-6 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS16780 e59922d3a7b317638ddd4bdaea19f69f 474 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 54 4.5E-6 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS16780 e59922d3a7b317638ddd4bdaea19f69f 474 Gene3D G3DSA:1.10.10.10 12 82 2.7E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS16780 e59922d3a7b317638ddd4bdaea19f69f 474 Gene3D G3DSA:3.40.640.10 120 352 1.3E-35 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS16780 e59922d3a7b317638ddd4bdaea19f69f 474 SUPERFAMILY SSF46785 14 83 2.18E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS03635 28af4aedebfad785b1907e49f1c3bbb0 367 SUPERFAMILY SSF56112 84 309 1.27E-26 T 29-03-2018 IPR011009 Protein kinase-like domain SMALA_RS03635 28af4aedebfad785b1907e49f1c3bbb0 367 Gene3D G3DSA:3.30.200.20 16 140 1.7E-4 T 29-03-2018 SMALA_RS03635 28af4aedebfad785b1907e49f1c3bbb0 367 Pfam PF01636 Phosphotransferase enzyme family 102 295 1.1E-20 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase SMALA_RS03635 28af4aedebfad785b1907e49f1c3bbb0 367 Gene3D G3DSA:3.90.1200.10 141 365 5.2E-16 T 29-03-2018 SMALA_RS06160 b5a719fa42ba4c4828b3c9aaa476c7d9 275 Gene3D G3DSA:1.10.260.40 1 87 1.7E-13 T 29-03-2018 SMALA_RS06160 b5a719fa42ba4c4828b3c9aaa476c7d9 275 SUPERFAMILY SSF47413 32 83 9.27E-8 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS06160 b5a719fa42ba4c4828b3c9aaa476c7d9 275 SMART SM00530 9 86 2.2E-9 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS06160 b5a719fa42ba4c4828b3c9aaa476c7d9 275 Pfam PF13560 Helix-turn-helix domain 5 89 3.4E-16 T 29-03-2018 SMALA_RS33755 ae3b54e4fb9edd63b2dda197faa20a50 140 SUPERFAMILY SSF48403 26 134 4.97E-21 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain SMALA_RS33755 ae3b54e4fb9edd63b2dda197faa20a50 140 SMART SM00248 51 80 3.8E-4 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 SMALA_RS33755 ae3b54e4fb9edd63b2dda197faa20a50 140 SMART SM00248 84 113 0.41 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 SMALA_RS33755 ae3b54e4fb9edd63b2dda197faa20a50 140 Pfam PF12796 Ankyrin repeats (3 copies) 28 112 1.3E-10 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain SMALA_RS33755 ae3b54e4fb9edd63b2dda197faa20a50 140 Gene3D G3DSA:1.25.40.20 16 140 4.7E-26 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain SMALA_RS09950 9dfe76a3d1783b0a87c6667c77d08db3 278 SUPERFAMILY SSF52833 102 256 2.16E-25 T 29-03-2018 IPR012336 Thioredoxin-like fold SMALA_RS09950 9dfe76a3d1783b0a87c6667c77d08db3 278 Gene3D G3DSA:3.40.30.10 98 278 1.1E-34 T 29-03-2018 SMALA_RS09950 9dfe76a3d1783b0a87c6667c77d08db3 278 Pfam PF13462 Thioredoxin 103 271 2.3E-27 T 29-03-2018 IPR012336 Thioredoxin-like fold SMALA_RS16405 bab018c18199f4500c62b1b56988236d 315 SUPERFAMILY SSF51569 50 295 6.7E-72 T 29-03-2018 SMALA_RS16405 bab018c18199f4500c62b1b56988236d 315 Pfam PF01791 DeoC/LacD family aldolase 45 293 7.1E-25 T 29-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 SMALA_RS16405 bab018c18199f4500c62b1b56988236d 315 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 52 277 1.5E-50 T 29-03-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 SMALA_RS16405 bab018c18199f4500c62b1b56988236d 315 SMART SM01133 49 296 1.3E-73 T 29-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 SMALA_RS16405 bab018c18199f4500c62b1b56988236d 315 Gene3D G3DSA:3.20.20.70 26 315 2.2E-93 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS16405 bab018c18199f4500c62b1b56988236d 315 PIRSF PIRSF001357 43 305 2.6E-80 T 29-03-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 SMALA_RS02225 634c9d90928fac32fb7dad5489c5db80 235 Pfam PF13353 4Fe-4S single cluster domain 25 170 6.4E-20 T 29-03-2018 SMALA_RS02225 634c9d90928fac32fb7dad5489c5db80 235 SUPERFAMILY SSF102114 33 97 1.12E-8 T 29-03-2018 SMALA_RS02225 634c9d90928fac32fb7dad5489c5db80 235 Gene3D G3DSA:3.20.20.70 13 145 6.0E-11 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS02225 634c9d90928fac32fb7dad5489c5db80 235 Pfam PF04055 Radical SAM superfamily 34 125 2.1E-7 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 SMALA_RS30355 254de7ad1860c85dc5eacb46b9196e3c 282 Gene3D G3DSA:3.40.190.10 83 170 1.2E-11 T 29-03-2018 SMALA_RS30355 254de7ad1860c85dc5eacb46b9196e3c 282 SUPERFAMILY SSF46785 1 80 4.09E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS30355 254de7ad1860c85dc5eacb46b9196e3c 282 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 4.3E-23 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS30355 254de7ad1860c85dc5eacb46b9196e3c 282 Gene3D G3DSA:1.10.10.10 1 82 2.5E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS30355 254de7ad1860c85dc5eacb46b9196e3c 282 Gene3D G3DSA:3.40.190.10 171 256 1.8E-6 T 29-03-2018 SMALA_RS30355 254de7ad1860c85dc5eacb46b9196e3c 282 Pfam PF03466 LysR substrate binding domain 83 259 6.3E-10 T 29-03-2018 IPR005119 LysR, substrate-binding SMALA_RS30355 254de7ad1860c85dc5eacb46b9196e3c 282 SUPERFAMILY SSF53850 83 264 1.18E-11 T 29-03-2018 SMALA_RS30355 254de7ad1860c85dc5eacb46b9196e3c 282 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.0E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS30355 254de7ad1860c85dc5eacb46b9196e3c 282 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.0E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS30355 254de7ad1860c85dc5eacb46b9196e3c 282 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.0E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS31450 02d6bbb796ad5552a424f4ebfda44eea 514 SUPERFAMILY SSF53720 35 492 1.22E-75 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMALA_RS31450 02d6bbb796ad5552a424f4ebfda44eea 514 Pfam PF00171 Aldehyde dehydrogenase family 46 487 1.2E-92 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS31450 02d6bbb796ad5552a424f4ebfda44eea 514 Gene3D G3DSA:3.40.309.10 286 461 2.2E-24 T 29-03-2018 SMALA_RS31450 02d6bbb796ad5552a424f4ebfda44eea 514 Gene3D G3DSA:3.40.605.10 20 285 7.5E-41 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS31850 6a2d2f71f0ff624d09525487069f7164 321 TIGRFAM TIGR03557 F420_G6P_family: F420-dependent oxidoreductase, G6PDH family 5 320 9.3E-153 T 29-03-2018 IPR019945 F420-dependent glucose-6-phosphate dehydrogenase-related SMALA_RS31850 6a2d2f71f0ff624d09525487069f7164 321 Gene3D G3DSA:3.20.20.30 4 321 1.6E-63 T 29-03-2018 SMALA_RS31850 6a2d2f71f0ff624d09525487069f7164 321 Pfam PF00296 Luciferase-like monooxygenase 10 291 3.5E-52 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS31850 6a2d2f71f0ff624d09525487069f7164 321 SUPERFAMILY SSF51679 1 319 5.59E-65 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS01845 2c1a4af8c3f79e3ca626dae8b00adbf1 430 Pfam PF00196 Bacterial regulatory proteins, luxR family 368 422 3.0E-19 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS01845 2c1a4af8c3f79e3ca626dae8b00adbf1 430 Gene3D G3DSA:3.30.565.10 214 359 4.1E-9 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS01845 2c1a4af8c3f79e3ca626dae8b00adbf1 430 SUPERFAMILY SSF55874 285 354 4.68E-5 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS01845 2c1a4af8c3f79e3ca626dae8b00adbf1 430 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 398 410 4.2E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS01845 2c1a4af8c3f79e3ca626dae8b00adbf1 430 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 382 398 4.2E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS01845 2c1a4af8c3f79e3ca626dae8b00adbf1 430 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 368 382 4.2E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS01845 2c1a4af8c3f79e3ca626dae8b00adbf1 430 ProSitePatterns PS00622 LuxR-type HTH domain signature. 382 409 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS01845 2c1a4af8c3f79e3ca626dae8b00adbf1 430 SUPERFAMILY SSF46894 357 426 1.02E-19 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS01845 2c1a4af8c3f79e3ca626dae8b00adbf1 430 SMART SM00421 365 422 3.9E-23 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS01845 2c1a4af8c3f79e3ca626dae8b00adbf1 430 Gene3D G3DSA:1.10.10.10 360 430 1.7E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS28360 4282e99b6870e682fac58a8ff6fdc3ee 482 Pfam PF01266 FAD dependent oxidoreductase 53 416 5.7E-52 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 SMALA_RS28360 4282e99b6870e682fac58a8ff6fdc3ee 482 SUPERFAMILY SSF51905 29 146 9.87E-42 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS28360 4282e99b6870e682fac58a8ff6fdc3ee 482 SUPERFAMILY SSF51905 202 336 9.87E-42 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS28360 4282e99b6870e682fac58a8ff6fdc3ee 482 Gene3D G3DSA:3.50.50.60 17 150 0.0075 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS28360 4282e99b6870e682fac58a8ff6fdc3ee 482 Gene3D G3DSA:3.30.9.10 151 232 1.0E-7 T 29-03-2018 SMALA_RS28360 4282e99b6870e682fac58a8ff6fdc3ee 482 Gene3D G3DSA:3.30.9.10 233 378 3.3E-25 T 29-03-2018 SMALA_RS31440 6dfeeb1fb3f59596729b5247ebe53302 377 Pfam PF00549 CoA-ligase 251 343 1.0E-10 T 29-03-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMALA_RS31440 6dfeeb1fb3f59596729b5247ebe53302 377 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 1 373 5.7E-118 T 29-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 SMALA_RS31440 6dfeeb1fb3f59596729b5247ebe53302 377 Gene3D G3DSA:3.30.1490.20 21 87 7.7E-22 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SMALA_RS31440 6dfeeb1fb3f59596729b5247ebe53302 377 SUPERFAMILY SSF56059 1 217 2.65E-61 T 29-03-2018 SMALA_RS31440 6dfeeb1fb3f59596729b5247ebe53302 377 Pfam PF08442 ATP-grasp domain 2 191 1.8E-64 T 29-03-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 SMALA_RS31440 6dfeeb1fb3f59596729b5247ebe53302 377 Hamap MF_00558 Succinate--CoA ligase [ADP-forming] subunit beta [sucC]. 1 374 36.36 T 29-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 SMALA_RS31440 6dfeeb1fb3f59596729b5247ebe53302 377 Gene3D G3DSA:3.30.470.20 88 226 2.4E-44 T 29-03-2018 SMALA_RS31440 6dfeeb1fb3f59596729b5247ebe53302 377 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 244 268 - T 29-03-2018 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMALA_RS31440 6dfeeb1fb3f59596729b5247ebe53302 377 Gene3D G3DSA:3.40.50.261 227 373 7.9E-35 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMALA_RS31440 6dfeeb1fb3f59596729b5247ebe53302 377 SUPERFAMILY SSF52210 226 372 4.84E-42 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMALA_RS31440 6dfeeb1fb3f59596729b5247ebe53302 377 PIRSF PIRSF001554 1 376 2.8E-126 T 29-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 SMALA_RS28655 a748c6a7abdf69cef6223685a50acf11 250 Gene3D G3DSA:3.30.360.10 125 216 2.5E-35 T 29-03-2018 SMALA_RS28655 a748c6a7abdf69cef6223685a50acf11 250 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 42 248 3.1E-51 T 29-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMALA_RS28655 a748c6a7abdf69cef6223685a50acf11 250 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 5 108 8.5E-23 T 29-03-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMALA_RS28655 a748c6a7abdf69cef6223685a50acf11 250 SUPERFAMILY SSF55347 109 217 1.59E-39 T 29-03-2018 SMALA_RS28655 a748c6a7abdf69cef6223685a50acf11 250 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 4 248 29.446 T 29-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMALA_RS28655 a748c6a7abdf69cef6223685a50acf11 250 Gene3D G3DSA:3.40.50.720 3 124 1.0E-26 T 29-03-2018 SMALA_RS28655 a748c6a7abdf69cef6223685a50acf11 250 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 111 247 1.4E-28 T 29-03-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMALA_RS28655 a748c6a7abdf69cef6223685a50acf11 250 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 130 147 - T 29-03-2018 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMALA_RS28655 a748c6a7abdf69cef6223685a50acf11 250 PIRSF PIRSF000161 2 250 1.7E-60 T 29-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMALA_RS28655 a748c6a7abdf69cef6223685a50acf11 250 SUPERFAMILY SSF51735 4 135 2.28E-33 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS04710 6372b5979018023041f76bb241a6762d 264 Gene3D G3DSA:1.10.10.10 2 77 3.7E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS04710 6372b5979018023041f76bb241a6762d 264 SUPERFAMILY SSF46785 16 89 1.6E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS04710 6372b5979018023041f76bb241a6762d 264 SUPERFAMILY SSF55781 87 258 2.62E-49 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS04710 6372b5979018023041f76bb241a6762d 264 Gene3D G3DSA:3.30.450.40 81 260 7.5E-51 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS04710 6372b5979018023041f76bb241a6762d 264 Pfam PF01614 Bacterial transcriptional regulator 134 255 1.8E-30 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal SMALA_RS04710 6372b5979018023041f76bb241a6762d 264 Pfam PF09339 IclR helix-turn-helix domain 18 69 2.2E-11 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMALA_RS04710 6372b5979018023041f76bb241a6762d 264 SMART SM00346 16 106 1.4E-16 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMALA_RS33960 25f931128761c645b5d80e6d230a678a 312 Gene3D G3DSA:1.10.3720.10 82 312 1.5E-39 T 29-03-2018 SMALA_RS33960 25f931128761c645b5d80e6d230a678a 312 SUPERFAMILY SSF161098 74 299 1.57E-48 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS33960 25f931128761c645b5d80e6d230a678a 312 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 109 300 1.2E-12 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS07920 dd3a05e219ee11adb3121cb6ee810b6d 597 Gene3D G3DSA:1.50.10.20 98 441 2.7E-45 T 29-03-2018 SMALA_RS07920 dd3a05e219ee11adb3121cb6ee810b6d 597 Pfam PF09492 Pectic acid lyase 166 383 1.1E-12 T 29-03-2018 IPR012669 Pectic acid lyase SMALA_RS07920 dd3a05e219ee11adb3121cb6ee810b6d 597 SUPERFAMILY SSF81853 253 408 6.15E-32 T 29-03-2018 SMALA_RS07920 dd3a05e219ee11adb3121cb6ee810b6d 597 SUPERFAMILY SSF81853 76 225 6.15E-32 T 29-03-2018 SMALA_RS13035 6eb9a3eb99902b67990be2687d3c52db 958 SUPERFAMILY SSF52374 23 172 1.73E-113 T 29-03-2018 SMALA_RS13035 6eb9a3eb99902b67990be2687d3c52db 958 SUPERFAMILY SSF52374 220 298 1.73E-113 T 29-03-2018 SMALA_RS13035 6eb9a3eb99902b67990be2687d3c52db 958 SUPERFAMILY SSF52374 513 778 1.73E-113 T 29-03-2018 SMALA_RS13035 6eb9a3eb99902b67990be2687d3c52db 958 Pfam PF09334 tRNA synthetases class I (M) 65 165 3.2E-13 T 29-03-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMALA_RS13035 6eb9a3eb99902b67990be2687d3c52db 958 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 68 78 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMALA_RS13035 6eb9a3eb99902b67990be2687d3c52db 958 Gene3D G3DSA:1.10.730.10 759 894 2.5E-24 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMALA_RS13035 6eb9a3eb99902b67990be2687d3c52db 958 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 18 957 21.341 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 SMALA_RS13035 6eb9a3eb99902b67990be2687d3c52db 958 SUPERFAMILY SSF47323 774 956 3.55E-29 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMALA_RS13035 6eb9a3eb99902b67990be2687d3c52db 958 PRINTS PR00985 Leucyl-tRNA synthetase signature 287 306 3.6E-52 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 SMALA_RS13035 6eb9a3eb99902b67990be2687d3c52db 958 PRINTS PR00985 Leucyl-tRNA synthetase signature 258 271 3.6E-52 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 SMALA_RS13035 6eb9a3eb99902b67990be2687d3c52db 958 PRINTS PR00985 Leucyl-tRNA synthetase signature 599 617 3.6E-52 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 SMALA_RS13035 6eb9a3eb99902b67990be2687d3c52db 958 PRINTS PR00985 Leucyl-tRNA synthetase signature 152 169 3.6E-52 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 SMALA_RS13035 6eb9a3eb99902b67990be2687d3c52db 958 PRINTS PR00985 Leucyl-tRNA synthetase signature 225 241 3.6E-52 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 SMALA_RS13035 6eb9a3eb99902b67990be2687d3c52db 958 PRINTS PR00985 Leucyl-tRNA synthetase signature 647 669 3.6E-52 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 SMALA_RS13035 6eb9a3eb99902b67990be2687d3c52db 958 PRINTS PR00985 Leucyl-tRNA synthetase signature 680 690 3.6E-52 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 SMALA_RS13035 6eb9a3eb99902b67990be2687d3c52db 958 SUPERFAMILY SSF50677 295 516 1.31E-43 T 29-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 SMALA_RS13035 6eb9a3eb99902b67990be2687d3c52db 958 Gene3D G3DSA:3.40.50.620 501 758 2.4E-51 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS13035 6eb9a3eb99902b67990be2687d3c52db 958 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 293 501 1.9E-60 T 29-03-2018 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 SMALA_RS13035 6eb9a3eb99902b67990be2687d3c52db 958 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 219 956 4.9E-218 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 SMALA_RS13035 6eb9a3eb99902b67990be2687d3c52db 958 Gene3D G3DSA:3.40.50.620 14 304 1.1E-60 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS13035 6eb9a3eb99902b67990be2687d3c52db 958 Gene3D G3DSA:3.90.740.10 305 500 2.9E-48 T 29-03-2018 SMALA_RS13035 6eb9a3eb99902b67990be2687d3c52db 958 Pfam PF08264 Anticodon-binding domain of tRNA 806 918 5.9E-14 T 29-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 SMALA_RS26195 e02bbeef7557dd2d258dcde18f931be5 483 Gene3D G3DSA:1.10.3210.10 242 439 1.1E-50 T 29-03-2018 SMALA_RS26195 e02bbeef7557dd2d258dcde18f931be5 483 TIGRFAM TIGR00277 HDIG: HDIG domain 272 361 3.5E-7 T 29-03-2018 IPR006675 HDIG domain SMALA_RS26195 e02bbeef7557dd2d258dcde18f931be5 483 Pfam PF01966 HD domain 273 393 3.2E-20 T 29-03-2018 IPR006674 HD domain SMALA_RS26195 e02bbeef7557dd2d258dcde18f931be5 483 SMART SM00471 267 402 2.4E-12 T 29-03-2018 IPR003607 HD/PDEase domain SMALA_RS26195 e02bbeef7557dd2d258dcde18f931be5 483 SUPERFAMILY SSF109604 256 432 1.08E-37 T 29-03-2018 SMALA_RS27525 48ca553bae3050b9517bd903da11e7d1 375 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 271 367 2.1E-24 T 29-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 SMALA_RS27525 48ca553bae3050b9517bd903da11e7d1 375 SUPERFAMILY SSF103025 9 282 9.58E-97 T 29-03-2018 SMALA_RS27525 48ca553bae3050b9517bd903da11e7d1 375 Gene3D G3DSA:3.30.1360.120 141 241 4.3E-29 T 29-03-2018 SMALA_RS27525 48ca553bae3050b9517bd903da11e7d1 375 Gene3D G3DSA:3.30.1360.120 8 140 3.5E-32 T 29-03-2018 SMALA_RS27525 48ca553bae3050b9517bd903da11e7d1 375 SUPERFAMILY SSF101790 292 374 5.89E-24 T 29-03-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain SMALA_RS27525 48ca553bae3050b9517bd903da11e7d1 375 Gene3D G3DSA:4.10.1250.10 242 285 3.5E-19 T 29-03-2018 SMALA_RS27525 48ca553bae3050b9517bd903da11e7d1 375 Gene3D G3DSA:2.40.30.110 290 375 6.1E-26 T 29-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 SMALA_RS27525 48ca553bae3050b9517bd903da11e7d1 375 Pfam PF01571 Aminomethyltransferase folate-binding domain 14 263 6.4E-92 T 29-03-2018 IPR006222 Glycine cleavage T-protein-like, N-terminal SMALA_RS27525 48ca553bae3050b9517bd903da11e7d1 375 PIRSF PIRSF006487 2 375 9.4E-101 T 29-03-2018 SMALA_RS27525 48ca553bae3050b9517bd903da11e7d1 375 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 9 373 9.5E-109 T 29-03-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 SMALA_RS27525 48ca553bae3050b9517bd903da11e7d1 375 Hamap MF_00259 Aminomethyltransferase [gcvT]. 7 373 44.699 T 29-03-2018 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 SMALA_RS30950 252bf158eb57fb9fe2fd9df7d0886e90 247 SUPERFAMILY SSF56214 30 130 6.8E-21 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 SMALA_RS30950 252bf158eb57fb9fe2fd9df7d0886e90 247 SUPERFAMILY SSF56214 137 201 7.59E-18 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 SMALA_RS30950 252bf158eb57fb9fe2fd9df7d0886e90 247 Gene3D G3DSA:3.90.470.20 30 148 1.4E-23 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 SMALA_RS30950 252bf158eb57fb9fe2fd9df7d0886e90 247 Gene3D G3DSA:3.90.470.20 149 223 1.4E-10 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 SMALA_RS30950 252bf158eb57fb9fe2fd9df7d0886e90 247 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 137 200 2.4E-11 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 SMALA_RS06845 c492a6d82067f465e210794bcad300dd 366 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 137 191 6.8E-7 T 29-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 SMALA_RS06845 c492a6d82067f465e210794bcad300dd 366 Gene3D G3DSA:3.30.360.10 128 354 2.1E-27 T 29-03-2018 SMALA_RS06845 c492a6d82067f465e210794bcad300dd 366 Gene3D G3DSA:3.40.50.720 1 127 9.1E-26 T 29-03-2018 SMALA_RS06845 c492a6d82067f465e210794bcad300dd 366 SUPERFAMILY SSF55347 137 298 4.09E-21 T 29-03-2018 SMALA_RS06845 c492a6d82067f465e210794bcad300dd 366 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 4 109 5.0E-20 T 29-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 SMALA_RS06845 c492a6d82067f465e210794bcad300dd 366 SUPERFAMILY SSF51735 3 150 2.74E-28 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS42665 1064d9c33626c2af6a6cf4cc239e9200 181 Gene3D G3DSA:3.10.450.50 1 181 1.0E-41 T 29-03-2018 SMALA_RS42665 1064d9c33626c2af6a6cf4cc239e9200 181 SUPERFAMILY SSF54427 11 180 1.07E-49 T 29-03-2018 IPR032710 NTF2-like domain SMALA_RS42665 1064d9c33626c2af6a6cf4cc239e9200 181 Pfam PF00866 Ring hydroxylating beta subunit 30 174 1.6E-45 T 29-03-2018 IPR000391 Ring-hydroxylating dioxygenase beta subunit GO:0003824|GO:0006725|GO:0055114 SMALA_RS03615 00d5cfe57058ba1e371cad81202e1cc1 388 SUPERFAMILY SSF53756 1 380 8.37E-76 T 29-03-2018 SMALA_RS03615 00d5cfe57058ba1e371cad81202e1cc1 388 Gene3D G3DSA:3.40.50.2000 1 202 6.7E-21 T 29-03-2018 SMALA_RS03615 00d5cfe57058ba1e371cad81202e1cc1 388 Pfam PF00534 Glycosyl transferases group 1 206 358 9.3E-24 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 SMALA_RS03615 00d5cfe57058ba1e371cad81202e1cc1 388 Pfam PF13439 Glycosyltransferase Family 4 14 195 8.7E-25 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 SMALA_RS03615 00d5cfe57058ba1e371cad81202e1cc1 388 Gene3D G3DSA:3.40.50.2000 203 362 5.0E-39 T 29-03-2018 SMALA_RS35990 889d2cccbc0e3515cbb9e3cd29145a21 417 Gene3D G3DSA:3.40.50.2000 1 231 1.2E-40 T 29-03-2018 SMALA_RS35990 889d2cccbc0e3515cbb9e3cd29145a21 417 Pfam PF06722 Protein of unknown function (DUF1205) 204 299 1.1E-16 T 29-03-2018 IPR010610 Domain of unknown function DUF1205 SMALA_RS35990 889d2cccbc0e3515cbb9e3cd29145a21 417 SUPERFAMILY SSF53756 1 415 5.02E-83 T 29-03-2018 SMALA_RS35990 889d2cccbc0e3515cbb9e3cd29145a21 417 TIGRFAM TIGR04516 glycosyl_450act: glycosyltransferase, activator-dependent family 1 415 9.0E-160 T 29-03-2018 IPR030953 Glycosyltransferase, activator-dependent family GO:0016757 SMALA_RS35990 889d2cccbc0e3515cbb9e3cd29145a21 417 Gene3D G3DSA:3.40.50.2000 232 397 2.6E-31 T 29-03-2018 SMALA_RS01260 f8b2f9ad6336f9e252be4d8277553774 392 Gene3D G3DSA:3.30.390.10 9 154 1.2E-32 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMALA_RS01260 f8b2f9ad6336f9e252be4d8277553774 392 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 52 151 4.7E-14 T 29-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain SMALA_RS01260 f8b2f9ad6336f9e252be4d8277553774 392 SUPERFAMILY SSF54826 23 152 4.61E-29 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMALA_RS01260 f8b2f9ad6336f9e252be4d8277553774 392 SUPERFAMILY SSF51604 139 381 9.04E-73 T 29-03-2018 IPR029065 Enolase C-terminal domain-like SMALA_RS01260 f8b2f9ad6336f9e252be4d8277553774 392 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 218 249 - T 29-03-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 SMALA_RS01260 f8b2f9ad6336f9e252be4d8277553774 392 Gene3D G3DSA:3.20.20.120 155 376 6.0E-65 T 29-03-2018 IPR029065 Enolase C-terminal domain-like SMALA_RS01260 f8b2f9ad6336f9e252be4d8277553774 392 Pfam PF13378 Enolase C-terminal domain-like 175 378 7.3E-64 T 29-03-2018 IPR029065 Enolase C-terminal domain-like SMALA_RS01260 f8b2f9ad6336f9e252be4d8277553774 392 SMART SM00922 171 268 2.5E-26 T 29-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal SMALA_RS07975 6513910372550d894f72d72d9ee210b1 332 SUPERFAMILY SSF50129 4 155 5.22E-17 T 29-03-2018 IPR011032 GroES-like SMALA_RS07975 6513910372550d894f72d72d9ee210b1 332 SUPERFAMILY SSF51735 122 264 1.63E-18 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS07975 6513910372550d894f72d72d9ee210b1 332 Gene3D G3DSA:3.40.50.720 149 258 2.9E-15 T 29-03-2018 SMALA_RS07975 6513910372550d894f72d72d9ee210b1 332 Gene3D G3DSA:3.90.180.10 1 148 9.4E-17 T 29-03-2018 SMALA_RS34370 72a77ee54be78216ecdc94279c4cca36 484 SUPERFAMILY SSF103473 5 466 4.45E-65 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS34370 72a77ee54be78216ecdc94279c4cca36 484 Gene3D G3DSA:1.20.1250.20 248 479 8.9E-22 T 29-03-2018 SMALA_RS34370 72a77ee54be78216ecdc94279c4cca36 484 Gene3D G3DSA:1.20.1250.20 7 238 3.2E-31 T 29-03-2018 SMALA_RS34370 72a77ee54be78216ecdc94279c4cca36 484 Pfam PF00083 Sugar (and other) transporter 59 467 1.1E-42 T 29-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 SMALA_RS22685 e7a7f7ff7945189418e8d54a9f4d0877 175 TIGRFAM TIGR00059 L17: ribosomal protein bL17 9 117 3.8E-41 T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS22685 e7a7f7ff7945189418e8d54a9f4d0877 175 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 5 116 27.325 T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS22685 e7a7f7ff7945189418e8d54a9f4d0877 175 Pfam PF01196 Ribosomal protein L17 20 116 1.4E-37 T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS22685 e7a7f7ff7945189418e8d54a9f4d0877 175 SUPERFAMILY SSF64263 1 117 9.03E-47 T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS22685 e7a7f7ff7945189418e8d54a9f4d0877 175 ProSitePatterns PS01167 Ribosomal protein L17 signature. 34 56 - T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS22685 e7a7f7ff7945189418e8d54a9f4d0877 175 Gene3D G3DSA:3.90.1030.10 1 117 1.0E-46 T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS20395 395504f23ad013835eafd3c063a59229 337 SUPERFAMILY SSF51735 135 307 7.31E-42 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS20395 395504f23ad013835eafd3c063a59229 337 Pfam PF00107 Zinc-binding dehydrogenase 173 298 6.5E-25 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMALA_RS20395 395504f23ad013835eafd3c063a59229 337 Gene3D G3DSA:3.90.180.10 3 336 8.4E-79 T 29-03-2018 SMALA_RS20395 395504f23ad013835eafd3c063a59229 337 SUPERFAMILY SSF50129 8 168 1.83E-38 T 29-03-2018 IPR011032 GroES-like SMALA_RS20395 395504f23ad013835eafd3c063a59229 337 SMART SM00829 13 334 3.8E-21 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS20395 395504f23ad013835eafd3c063a59229 337 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 30 129 7.2E-8 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS39375 5a7659893353de4e1120160ff3777939 253 SUPERFAMILY SSF48008 123 251 2.09E-24 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS39375 5a7659893353de4e1120160ff3777939 253 Pfam PF07729 FCD domain 123 246 1.9E-23 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS39375 5a7659893353de4e1120160ff3777939 253 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 70 86 3.4E-12 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS39375 5a7659893353de4e1120160ff3777939 253 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 56 70 3.4E-12 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS39375 5a7659893353de4e1120160ff3777939 253 Gene3D G3DSA:1.10.10.10 25 100 3.3E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS39375 5a7659893353de4e1120160ff3777939 253 SMART SM00345 37 98 9.8E-23 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS39375 5a7659893353de4e1120160ff3777939 253 SUPERFAMILY SSF46785 26 102 3.08E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS39375 5a7659893353de4e1120160ff3777939 253 SMART SM00895 123 246 5.1E-21 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS39375 5a7659893353de4e1120160ff3777939 253 Gene3D G3DSA:1.20.120.530 103 253 9.8E-26 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS39375 5a7659893353de4e1120160ff3777939 253 Pfam PF00392 Bacterial regulatory proteins, gntR family 35 91 1.4E-20 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS27265 b62beeea7a6712664e613278c1977b2c 305 SUPERFAMILY SSF160964 24 58 3.4E-6 T 29-03-2018 SMALA_RS27265 b62beeea7a6712664e613278c1977b2c 305 Gene3D G3DSA:1.20.58.370 5 57 1.1E-5 T 29-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain SMALA_RS27265 b62beeea7a6712664e613278c1977b2c 305 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 105 297 1.6E-15 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS27265 b62beeea7a6712664e613278c1977b2c 305 SUPERFAMILY SSF161098 70 295 3.92E-55 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS27265 b62beeea7a6712664e613278c1977b2c 305 Gene3D G3DSA:1.10.3720.10 78 305 8.0E-42 T 29-03-2018 SMALA_RS09780 5d05616aa09eee710f78062fcaa612f7 911 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 193 286 6.8E-28 T 29-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 SMALA_RS09780 5d05616aa09eee710f78062fcaa612f7 911 SMART SM00474 329 500 9.1E-4 T 29-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 SMALA_RS09780 5d05616aa09eee710f78062fcaa612f7 911 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 23 191 2.4E-55 T 29-03-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 SMALA_RS09780 5d05616aa09eee710f78062fcaa612f7 911 TIGRFAM TIGR00593 pola: DNA polymerase I 24 909 1.4E-298 T 29-03-2018 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMALA_RS09780 5d05616aa09eee710f78062fcaa612f7 911 PRINTS PR00868 DNA-polymerase family A (pol I) signature 636 658 1.0E-75 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMALA_RS09780 5d05616aa09eee710f78062fcaa612f7 911 PRINTS PR00868 DNA-polymerase family A (pol I) signature 682 705 1.0E-75 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMALA_RS09780 5d05616aa09eee710f78062fcaa612f7 911 PRINTS PR00868 DNA-polymerase family A (pol I) signature 712 725 1.0E-75 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMALA_RS09780 5d05616aa09eee710f78062fcaa612f7 911 PRINTS PR00868 DNA-polymerase family A (pol I) signature 827 843 1.0E-75 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMALA_RS09780 5d05616aa09eee710f78062fcaa612f7 911 PRINTS PR00868 DNA-polymerase family A (pol I) signature 857 870 1.0E-75 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMALA_RS09780 5d05616aa09eee710f78062fcaa612f7 911 PRINTS PR00868 DNA-polymerase family A (pol I) signature 659 674 1.0E-75 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMALA_RS09780 5d05616aa09eee710f78062fcaa612f7 911 PRINTS PR00868 DNA-polymerase family A (pol I) signature 736 761 1.0E-75 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMALA_RS09780 5d05616aa09eee710f78062fcaa612f7 911 PRINTS PR00868 DNA-polymerase family A (pol I) signature 773 784 1.0E-75 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMALA_RS09780 5d05616aa09eee710f78062fcaa612f7 911 PRINTS PR00868 DNA-polymerase family A (pol I) signature 795 806 1.0E-75 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMALA_RS09780 5d05616aa09eee710f78062fcaa612f7 911 Gene3D G3DSA:1.10.150.20 205 282 7.4E-26 T 29-03-2018 SMALA_RS09780 5d05616aa09eee710f78062fcaa612f7 911 SMART SM00482 667 874 3.1E-114 T 29-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMALA_RS09780 5d05616aa09eee710f78062fcaa612f7 911 Gene3D G3DSA:1.20.1060.10 476 634 1.4E-41 T 29-03-2018 SMALA_RS09780 5d05616aa09eee710f78062fcaa612f7 911 SUPERFAMILY SSF53098 335 501 1.21E-28 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SMALA_RS09780 5d05616aa09eee710f78062fcaa612f7 911 Gene3D G3DSA:3.40.50.1010 22 204 3.2E-68 T 29-03-2018 IPR029060 PIN domain-like SMALA_RS09780 5d05616aa09eee710f78062fcaa612f7 911 Gene3D G3DSA:3.30.420.10 313 475 3.8E-13 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SMALA_RS09780 5d05616aa09eee710f78062fcaa612f7 911 SMART SM00475 20 282 8.6E-143 T 29-03-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 SMALA_RS09780 5d05616aa09eee710f78062fcaa612f7 911 Gene3D G3DSA:3.30.70.370 736 911 6.7E-46 T 29-03-2018 SMALA_RS09780 5d05616aa09eee710f78062fcaa612f7 911 Gene3D G3DSA:3.30.70.370 635 730 8.4E-16 T 29-03-2018 SMALA_RS09780 5d05616aa09eee710f78062fcaa612f7 911 SUPERFAMILY SSF88723 21 191 7.46E-54 T 29-03-2018 IPR029060 PIN domain-like SMALA_RS09780 5d05616aa09eee710f78062fcaa612f7 911 SUPERFAMILY SSF47807 192 300 6.58E-30 T 29-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 SMALA_RS09780 5d05616aa09eee710f78062fcaa612f7 911 SMART SM00279 194 229 1.6E-14 T 29-03-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 SMALA_RS09780 5d05616aa09eee710f78062fcaa612f7 911 SUPERFAMILY SSF56672 507 908 1.56E-139 T 29-03-2018 SMALA_RS09780 5d05616aa09eee710f78062fcaa612f7 911 Pfam PF00476 DNA polymerase family A 534 907 4.6E-142 T 29-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMALA_RS38050 2f7e68962197e362ecaa5463fd73e854 366 Pfam PF08279 HTH domain 7 62 6.5E-10 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 SMALA_RS38050 2f7e68962197e362ecaa5463fd73e854 366 Gene3D G3DSA:1.10.260.40 34 138 5.7E-4 T 29-03-2018 SMALA_RS38050 2f7e68962197e362ecaa5463fd73e854 366 PIRSF PIRSF016838 1 53 0.13 T 29-03-2018 IPR028349 Protein PafC SMALA_RS38050 2f7e68962197e362ecaa5463fd73e854 366 PIRSF PIRSF016838 67 254 8.3E-15 T 29-03-2018 IPR028349 Protein PafC SMALA_RS38050 2f7e68962197e362ecaa5463fd73e854 366 PIRSF PIRSF016838 284 352 0.62 T 29-03-2018 IPR028349 Protein PafC SMALA_RS38050 2f7e68962197e362ecaa5463fd73e854 366 SUPERFAMILY SSF46785 5 64 4.64E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS38050 2f7e68962197e362ecaa5463fd73e854 366 Pfam PF13280 WYL domain 144 344 1.7E-35 T 29-03-2018 IPR026881 WYL domain SMALA_RS38050 2f7e68962197e362ecaa5463fd73e854 366 Gene3D G3DSA:1.10.10.10 1 33 6.8E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS06705 185d3adf9f1f7c3e1f5b036058e6a27b 312 SUPERFAMILY SSF52540 6 275 1.97E-72 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS06705 185d3adf9f1f7c3e1f5b036058e6a27b 312 TIGRFAM TIGR00750 lao: LAO/AO transport system ATPase 14 310 6.0E-93 T 29-03-2018 IPR005129 SIMIBI class G3E GTPase, ArgK/MeaB GO:0003924|GO:0005525 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMALA_RS06705 185d3adf9f1f7c3e1f5b036058e6a27b 312 Gene3D G3DSA:3.40.50.300 45 252 3.8E-36 T 29-03-2018 SMALA_RS06705 185d3adf9f1f7c3e1f5b036058e6a27b 312 Gene3D G3DSA:1.20.5.170 6 42 4.8E-6 T 29-03-2018 SMALA_RS06705 185d3adf9f1f7c3e1f5b036058e6a27b 312 Pfam PF03308 ArgK protein 19 276 1.2E-90 T 29-03-2018 SMALA_RS06705 185d3adf9f1f7c3e1f5b036058e6a27b 312 SMART SM00382 46 197 1.4E-6 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS08405 ab5415bb718cd26a567cff28e77efb75 587 ProSitePatterns PS01182 Glycosyl hydrolases family 35 putative active site. 148 160 - T 29-03-2018 IPR019801 Glycoside hydrolase, family 35, conserved site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 SMALA_RS08405 ab5415bb718cd26a567cff28e77efb75 587 Gene3D G3DSA:3.20.20.80 2 331 1.7E-82 T 29-03-2018 SMALA_RS08405 ab5415bb718cd26a567cff28e77efb75 587 Gene3D G3DSA:2.60.120.260 474 587 3.9E-25 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS08405 ab5415bb718cd26a567cff28e77efb75 587 SUPERFAMILY SSF51445 6 327 7.86E-102 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS08405 ab5415bb718cd26a567cff28e77efb75 587 Gene3D G3DSA:2.60.120.260 353 473 5.8E-38 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS08405 ab5415bb718cd26a567cff28e77efb75 587 PIRSF PIRSF006336 2 587 7.5E-202 T 29-03-2018 IPR026283 Beta-galactosidase 1-like GO:0004565 SMALA_RS08405 ab5415bb718cd26a567cff28e77efb75 587 Pfam PF01301 Glycosyl hydrolases family 35 13 324 3.2E-108 T 29-03-2018 IPR031330 Glycoside hydrolase 35, catalytic domain KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 SMALA_RS08405 ab5415bb718cd26a567cff28e77efb75 587 PRINTS PR00742 Glycosyl hydrolase family 35 signature 36 54 3.0E-55 T 29-03-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 SMALA_RS08405 ab5415bb718cd26a567cff28e77efb75 587 PRINTS PR00742 Glycosyl hydrolase family 35 signature 91 110 3.0E-55 T 29-03-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 SMALA_RS08405 ab5415bb718cd26a567cff28e77efb75 587 PRINTS PR00742 Glycosyl hydrolase family 35 signature 15 32 3.0E-55 T 29-03-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 SMALA_RS08405 ab5415bb718cd26a567cff28e77efb75 587 PRINTS PR00742 Glycosyl hydrolase family 35 signature 232 247 3.0E-55 T 29-03-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 SMALA_RS08405 ab5415bb718cd26a567cff28e77efb75 587 PRINTS PR00742 Glycosyl hydrolase family 35 signature 524 540 3.0E-55 T 29-03-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 SMALA_RS08405 ab5415bb718cd26a567cff28e77efb75 587 PRINTS PR00742 Glycosyl hydrolase family 35 signature 268 283 3.0E-55 T 29-03-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 SMALA_RS08405 ab5415bb718cd26a567cff28e77efb75 587 PRINTS PR00742 Glycosyl hydrolase family 35 signature 294 310 3.0E-55 T 29-03-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 SMALA_RS08405 ab5415bb718cd26a567cff28e77efb75 587 PRINTS PR00742 Glycosyl hydrolase family 35 signature 146 161 3.0E-55 T 29-03-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 SMALA_RS08405 ab5415bb718cd26a567cff28e77efb75 587 SUPERFAMILY SSF49785 442 573 5.71E-34 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS26645 f507b51ff967d2bbccaa52a24493711b 229 Gene3D G3DSA:1.10.357.10 2 224 1.1E-36 T 29-03-2018 SMALA_RS26645 f507b51ff967d2bbccaa52a24493711b 229 Pfam PF00440 Bacterial regulatory proteins, tetR family 10 57 5.9E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS26645 f507b51ff967d2bbccaa52a24493711b 229 SUPERFAMILY SSF46689 5 71 2.67E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS01780 bdb4b36d1c910494a2987b210d4d936f 342 Gene3D G3DSA:1.10.260.40 19 57 1.9E-23 T 29-03-2018 SMALA_RS01780 bdb4b36d1c910494a2987b210d4d936f 342 SUPERFAMILY SSF53822 62 332 1.91E-66 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SMALA_RS01780 bdb4b36d1c910494a2987b210d4d936f 342 Gene3D G3DSA:3.40.50.2300 58 176 2.1E-33 T 29-03-2018 SMALA_RS01780 bdb4b36d1c910494a2987b210d4d936f 342 Gene3D G3DSA:1.10.10.60 2 18 0.098 T 29-03-2018 SMALA_RS01780 bdb4b36d1c910494a2987b210d4d936f 342 Gene3D G3DSA:3.40.50.2300 177 308 1.7E-42 T 29-03-2018 SMALA_RS01780 bdb4b36d1c910494a2987b210d4d936f 342 SMART SM00354 3 73 1.6E-29 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS01780 bdb4b36d1c910494a2987b210d4d936f 342 SUPERFAMILY SSF47413 2 61 3.31E-17 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS01780 bdb4b36d1c910494a2987b210d4d936f 342 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 50 4.3E-17 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS01780 bdb4b36d1c910494a2987b210d4d936f 342 Pfam PF13377 Periplasmic binding protein-like domain 170 328 2.2E-34 T 29-03-2018 SMALA_RS20405 a8d81bf257f875c72f8571ccfef6192b 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.1E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS20405 a8d81bf257f875c72f8571ccfef6192b 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.1E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS20405 a8d81bf257f875c72f8571ccfef6192b 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.1E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS20405 a8d81bf257f875c72f8571ccfef6192b 300 Gene3D G3DSA:3.40.190.10 93 184 4.8E-24 T 29-03-2018 SMALA_RS20405 a8d81bf257f875c72f8571ccfef6192b 300 Pfam PF03466 LysR substrate binding domain 93 296 4.1E-46 T 29-03-2018 IPR005119 LysR, substrate-binding SMALA_RS20405 a8d81bf257f875c72f8571ccfef6192b 300 Gene3D G3DSA:3.40.190.10 185 268 2.0E-18 T 29-03-2018 SMALA_RS20405 a8d81bf257f875c72f8571ccfef6192b 300 Gene3D G3DSA:1.10.10.10 1 83 9.9E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS20405 a8d81bf257f875c72f8571ccfef6192b 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 1.8E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS20405 a8d81bf257f875c72f8571ccfef6192b 300 SUPERFAMILY SSF53850 94 298 9.51E-45 T 29-03-2018 SMALA_RS20405 a8d81bf257f875c72f8571ccfef6192b 300 SUPERFAMILY SSF46785 2 84 2.56E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS30530 588840286605b3436fe469f38cc418cf 456 SUPERFAMILY SSF51556 61 376 1.5E-96 T 29-03-2018 IPR032466 Metal-dependent hydrolase SMALA_RS30530 588840286605b3436fe469f38cc418cf 456 SUPERFAMILY SSF51338 336 453 3.74E-31 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS30530 588840286605b3436fe469f38cc418cf 456 Gene3D G3DSA:3.20.20.140 74 392 5.2E-66 T 29-03-2018 SMALA_RS30530 588840286605b3436fe469f38cc418cf 456 SUPERFAMILY SSF51338 3 75 5.04E-10 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS30530 588840286605b3436fe469f38cc418cf 456 Gene3D G3DSA:2.30.40.10 1 73 3.5E-16 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS30530 588840286605b3436fe469f38cc418cf 456 Pfam PF01979 Amidohydrolase family 58 406 1.6E-63 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 SMALA_RS01725 9985a228e131431999d3300c506bc192 240 SUPERFAMILY SSF46689 25 91 4.29E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS01725 9985a228e131431999d3300c506bc192 240 Gene3D G3DSA:1.10.10.60 17 87 1.1E-17 T 29-03-2018 SMALA_RS01725 9985a228e131431999d3300c506bc192 240 Gene3D G3DSA:1.10.357.10 88 239 2.3E-30 T 29-03-2018 SMALA_RS01725 9985a228e131431999d3300c506bc192 240 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 94 238 2.3E-19 T 29-03-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 SMALA_RS01725 9985a228e131431999d3300c506bc192 240 Pfam PF00440 Bacterial regulatory proteins, tetR family 37 81 2.7E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS01725 9985a228e131431999d3300c506bc192 240 SUPERFAMILY SSF48498 99 237 1.72E-22 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS25250 0c00ee5b04ce2a40da6c246dd8c46388 228 SUPERFAMILY SSF53335 22 215 2.32E-37 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS25250 0c00ee5b04ce2a40da6c246dd8c46388 228 Pfam PF13649 Methyltransferase domain 50 144 1.0E-20 T 29-03-2018 SMALA_RS25250 0c00ee5b04ce2a40da6c246dd8c46388 228 Gene3D G3DSA:3.40.50.150 9 218 4.8E-39 T 29-03-2018 SMALA_RS41050 d310c084659237df50217420dc08d3d0 280 Gene3D G3DSA:1.10.3720.10 1 277 2.0E-40 T 29-03-2018 SMALA_RS41050 d310c084659237df50217420dc08d3d0 280 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 77 270 1.3E-13 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS41050 d310c084659237df50217420dc08d3d0 280 SUPERFAMILY SSF161098 45 266 2.35E-49 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS19130 4782e992292d5a9e6d2f91a4977ae238 212 Gene3D G3DSA:2.60.40.1240 72 211 6.9E-4 T 29-03-2018 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain SMALA_RS26430 ba106787ede6e68fa17eac8f4f40d89c 169 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 28 110 1.1E-14 T 29-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 SMALA_RS26430 ba106787ede6e68fa17eac8f4f40d89c 169 SUPERFAMILY SSF50475 25 151 1.54E-26 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS26430 ba106787ede6e68fa17eac8f4f40d89c 169 Gene3D G3DSA:2.30.110.10 20 167 3.4E-25 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS42660 6cf4883b14ead37ef999bdd443e71129 453 SUPERFAMILY SSF55961 164 446 4.55E-40 T 29-03-2018 SMALA_RS42660 6cf4883b14ead37ef999bdd443e71129 453 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 198 435 8.0E-18 T 29-03-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 SMALA_RS42660 6cf4883b14ead37ef999bdd443e71129 453 SUPERFAMILY SSF50022 14 161 1.1E-44 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMALA_RS42660 6cf4883b14ead37ef999bdd443e71129 453 ProSitePatterns PS00570 Bacterial ring hydroxylating dioxygenases alpha-subunit signature. 89 112 - T 29-03-2018 IPR015881 Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site GO:0005506|GO:0016705|GO:0051537|GO:0055114 SMALA_RS42660 6cf4883b14ead37ef999bdd443e71129 453 Gene3D G3DSA:3.90.380.10 153 451 1.4E-49 T 29-03-2018 SMALA_RS42660 6cf4883b14ead37ef999bdd443e71129 453 Gene3D G3DSA:2.102.10.10 44 152 4.7E-21 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMALA_RS42660 6cf4883b14ead37ef999bdd443e71129 453 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 61 76 8.2E-50 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 SMALA_RS42660 6cf4883b14ead37ef999bdd443e71129 453 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 187 209 8.2E-50 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 SMALA_RS42660 6cf4883b14ead37ef999bdd443e71129 453 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 103 123 8.2E-50 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 SMALA_RS42660 6cf4883b14ead37ef999bdd443e71129 453 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 31 56 8.2E-50 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 SMALA_RS42660 6cf4883b14ead37ef999bdd443e71129 453 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 147 173 8.2E-50 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 SMALA_RS42660 6cf4883b14ead37ef999bdd443e71129 453 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 82 102 8.2E-50 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 SMALA_RS42660 6cf4883b14ead37ef999bdd443e71129 453 Pfam PF00355 Rieske [2Fe-2S] domain 47 128 2.4E-18 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMALA_RS01750 7646c30fa4eb8b6a6e860ecc7a9809bc 269 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 59 267 1.8E-27 T 29-03-2018 SMALA_RS01750 7646c30fa4eb8b6a6e860ecc7a9809bc 269 Gene3D G3DSA:3.40.50.720 1 269 7.8E-50 T 29-03-2018 SMALA_RS01750 7646c30fa4eb8b6a6e860ecc7a9809bc 269 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 185 204 5.0E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS01750 7646c30fa4eb8b6a6e860ecc7a9809bc 269 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 99 110 5.0E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS01750 7646c30fa4eb8b6a6e860ecc7a9809bc 269 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 166 174 5.0E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS01750 7646c30fa4eb8b6a6e860ecc7a9809bc 269 SUPERFAMILY SSF51735 60 267 3.72E-47 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS01750 7646c30fa4eb8b6a6e860ecc7a9809bc 269 SUPERFAMILY SSF51735 1 32 3.72E-47 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS01750 7646c30fa4eb8b6a6e860ecc7a9809bc 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 185 204 8.2E-16 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS01750 7646c30fa4eb8b6a6e860ecc7a9809bc 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 223 8.2E-16 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS01750 7646c30fa4eb8b6a6e860ecc7a9809bc 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 236 256 8.2E-16 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS01750 7646c30fa4eb8b6a6e860ecc7a9809bc 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 99 110 8.2E-16 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS01750 7646c30fa4eb8b6a6e860ecc7a9809bc 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 176 8.2E-16 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS30280 15bbcbf08c1ee357ea4e74e1cacf4aaa 564 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 470 486 - T 29-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 SMALA_RS30280 15bbcbf08c1ee357ea4e74e1cacf4aaa 564 SUPERFAMILY SSF56014 172 332 4.45E-45 T 29-03-2018 SMALA_RS30280 15bbcbf08c1ee357ea4e74e1cacf4aaa 564 SUPERFAMILY SSF55124 304 436 2.47E-19 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 SMALA_RS30280 15bbcbf08c1ee357ea4e74e1cacf4aaa 564 Gene3D G3DSA:3.30.413.10 173 289 1.1E-26 T 29-03-2018 SMALA_RS30280 15bbcbf08c1ee357ea4e74e1cacf4aaa 564 PRINTS PR00397 Sirohaem Fe-binding site signature 470 488 1.4E-9 T 29-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 SMALA_RS30280 15bbcbf08c1ee357ea4e74e1cacf4aaa 564 PRINTS PR00397 Sirohaem Fe-binding site signature 425 443 1.4E-9 T 29-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 SMALA_RS30280 15bbcbf08c1ee357ea4e74e1cacf4aaa 564 SUPERFAMILY SSF55124 21 171 2.18E-38 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 SMALA_RS30280 15bbcbf08c1ee357ea4e74e1cacf4aaa 564 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 425 558 1.6E-9 T 29-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 SMALA_RS30280 15bbcbf08c1ee357ea4e74e1cacf4aaa 564 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 172 324 1.2E-38 T 29-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 SMALA_RS30280 15bbcbf08c1ee357ea4e74e1cacf4aaa 564 Gene3D G3DSA:3.30.413.10 424 564 6.9E-30 T 29-03-2018 SMALA_RS30280 15bbcbf08c1ee357ea4e74e1cacf4aaa 564 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 348 413 3.4E-13 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 SMALA_RS30280 15bbcbf08c1ee357ea4e74e1cacf4aaa 564 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 101 162 2.1E-21 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 SMALA_RS30280 15bbcbf08c1ee357ea4e74e1cacf4aaa 564 Gene3D G3DSA:3.90.480.10 290 420 1.5E-28 T 29-03-2018 SMALA_RS30280 15bbcbf08c1ee357ea4e74e1cacf4aaa 564 SUPERFAMILY SSF56014 421 562 3.27E-37 T 29-03-2018 SMALA_RS33100 a4d83e83cb728929f36a731cff718cff 379 PRINTS PR00096 Glutamine amidotransferase superfamily signature 349 362 8.0E-11 T 29-03-2018 SMALA_RS33100 a4d83e83cb728929f36a731cff718cff 379 PRINTS PR00096 Glutamine amidotransferase superfamily signature 258 269 8.0E-11 T 29-03-2018 SMALA_RS33100 a4d83e83cb728929f36a731cff718cff 379 PRINTS PR00096 Glutamine amidotransferase superfamily signature 230 239 8.0E-11 T 29-03-2018 SMALA_RS33100 a4d83e83cb728929f36a731cff718cff 379 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 227 241 1.1E-29 T 29-03-2018 SMALA_RS33100 a4d83e83cb728929f36a731cff718cff 379 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 258 274 1.1E-29 T 29-03-2018 SMALA_RS33100 a4d83e83cb728929f36a731cff718cff 379 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 300 311 1.1E-29 T 29-03-2018 SMALA_RS33100 a4d83e83cb728929f36a731cff718cff 379 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 275 292 1.1E-29 T 29-03-2018 SMALA_RS33100 a4d83e83cb728929f36a731cff718cff 379 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 188 202 1.1E-29 T 29-03-2018 SMALA_RS33100 a4d83e83cb728929f36a731cff718cff 379 SUPERFAMILY SSF52021 11 144 4.45E-56 T 29-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SMALA_RS33100 a4d83e83cb728929f36a731cff718cff 379 PRINTS PR00097 Anthranilate synthase component II signature 349 362 1.8E-5 T 29-03-2018 SMALA_RS33100 a4d83e83cb728929f36a731cff718cff 379 PRINTS PR00097 Anthranilate synthase component II signature 230 239 1.8E-5 T 29-03-2018 SMALA_RS33100 a4d83e83cb728929f36a731cff718cff 379 PRINTS PR00097 Anthranilate synthase component II signature 258 269 1.8E-5 T 29-03-2018 SMALA_RS33100 a4d83e83cb728929f36a731cff718cff 379 Pfam PF00117 Glutamine amidotransferase class-I 191 372 2.4E-37 T 29-03-2018 IPR017926 Glutamine amidotransferase SMALA_RS33100 a4d83e83cb728929f36a731cff718cff 379 Gene3D G3DSA:3.50.30.20 9 152 5.7E-64 T 29-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SMALA_RS33100 a4d83e83cb728929f36a731cff718cff 379 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 12 138 9.5E-53 T 29-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SMALA_RS33100 a4d83e83cb728929f36a731cff718cff 379 Gene3D G3DSA:3.40.50.880 153 379 1.2E-48 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS33100 a4d83e83cb728929f36a731cff718cff 379 SMART SM01097 10 140 2.1E-88 T 29-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SMALA_RS33100 a4d83e83cb728929f36a731cff718cff 379 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 10 378 46.049 T 29-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SMALA_RS33100 a4d83e83cb728929f36a731cff718cff 379 SUPERFAMILY SSF52317 162 377 4.28E-50 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS33100 a4d83e83cb728929f36a731cff718cff 379 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 12 375 1.2E-134 T 29-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SMALA_RS23310 ca1e68bbe5bcd72d8bcad56543b45243 653 SUPERFAMILY SSF52540 8 254 2.06E-69 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS23310 ca1e68bbe5bcd72d8bcad56543b45243 653 Gene3D G3DSA:3.30.70.870 373 447 1.7E-5 T 29-03-2018 SMALA_RS23310 ca1e68bbe5bcd72d8bcad56543b45243 653 PRINTS PR00315 GTP-binding elongation factor signature 12 25 2.0E-16 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMALA_RS23310 ca1e68bbe5bcd72d8bcad56543b45243 653 PRINTS PR00315 GTP-binding elongation factor signature 58 66 2.0E-16 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMALA_RS23310 ca1e68bbe5bcd72d8bcad56543b45243 653 PRINTS PR00315 GTP-binding elongation factor signature 78 88 2.0E-16 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMALA_RS23310 ca1e68bbe5bcd72d8bcad56543b45243 653 PRINTS PR00315 GTP-binding elongation factor signature 94 105 2.0E-16 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMALA_RS23310 ca1e68bbe5bcd72d8bcad56543b45243 653 PRINTS PR00315 GTP-binding elongation factor signature 130 139 2.0E-16 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMALA_RS23310 ca1e68bbe5bcd72d8bcad56543b45243 653 Gene3D G3DSA:2.40.30.10 261 372 2.0E-7 T 29-03-2018 SMALA_RS23310 ca1e68bbe5bcd72d8bcad56543b45243 653 Gene3D G3DSA:3.30.230.10 457 574 6.2E-17 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SMALA_RS23310 ca1e68bbe5bcd72d8bcad56543b45243 653 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site SMALA_RS23310 ca1e68bbe5bcd72d8bcad56543b45243 653 SUPERFAMILY SSF54980 567 638 2.64E-6 T 29-03-2018 IPR035647 EF-G domain III/V-like SMALA_RS23310 ca1e68bbe5bcd72d8bcad56543b45243 653 SUPERFAMILY SSF50447 239 363 1.0E-5 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain SMALA_RS23310 ca1e68bbe5bcd72d8bcad56543b45243 653 Pfam PF00679 Elongation factor G C-terminus 567 638 3.2E-8 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like SMALA_RS23310 ca1e68bbe5bcd72d8bcad56543b45243 653 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 145 2.6E-27 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 SMALA_RS23310 ca1e68bbe5bcd72d8bcad56543b45243 653 SMART SM00889 459 564 2.6E-5 T 29-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 SMALA_RS23310 ca1e68bbe5bcd72d8bcad56543b45243 653 SUPERFAMILY SSF54980 387 446 1.44E-5 T 29-03-2018 IPR035647 EF-G domain III/V-like SMALA_RS23310 ca1e68bbe5bcd72d8bcad56543b45243 653 Gene3D G3DSA:3.30.70.240 575 637 6.1E-7 T 29-03-2018 SMALA_RS23310 ca1e68bbe5bcd72d8bcad56543b45243 653 Pfam PF03764 Elongation factor G, domain IV 465 563 1.7E-15 T 29-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 SMALA_RS23310 ca1e68bbe5bcd72d8bcad56543b45243 653 SUPERFAMILY SSF54211 467 564 7.21E-14 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SMALA_RS23310 ca1e68bbe5bcd72d8bcad56543b45243 653 Pfam PF00009 Elongation factor Tu GTP binding domain 9 254 6.1E-53 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMALA_RS23310 ca1e68bbe5bcd72d8bcad56543b45243 653 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 228 250 9.9E-19 T 29-03-2018 SMALA_RS23310 ca1e68bbe5bcd72d8bcad56543b45243 653 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 116 139 9.9E-19 T 29-03-2018 SMALA_RS23310 ca1e68bbe5bcd72d8bcad56543b45243 653 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 487 501 9.9E-19 T 29-03-2018 SMALA_RS23310 ca1e68bbe5bcd72d8bcad56543b45243 653 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 536 553 9.9E-19 T 29-03-2018 SMALA_RS23310 ca1e68bbe5bcd72d8bcad56543b45243 653 Gene3D G3DSA:3.40.50.300 6 258 8.7E-40 T 29-03-2018 SMALA_RS16210 72080853fca61727a50e61faf7e64c81 426 Gene3D G3DSA:3.30.390.10 3 127 6.6E-50 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMALA_RS16210 72080853fca61727a50e61faf7e64c81 426 PRINTS PR00148 Enolase signature 361 378 2.8E-47 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMALA_RS16210 72080853fca61727a50e61faf7e64c81 426 PRINTS PR00148 Enolase signature 309 320 2.8E-47 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMALA_RS16210 72080853fca61727a50e61faf7e64c81 426 PRINTS PR00148 Enolase signature 332 346 2.8E-47 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMALA_RS16210 72080853fca61727a50e61faf7e64c81 426 PRINTS PR00148 Enolase signature 107 123 2.8E-47 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMALA_RS16210 72080853fca61727a50e61faf7e64c81 426 PRINTS PR00148 Enolase signature 161 174 2.8E-47 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMALA_RS16210 72080853fca61727a50e61faf7e64c81 426 PRINTS PR00148 Enolase signature 37 51 2.8E-47 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMALA_RS16210 72080853fca61727a50e61faf7e64c81 426 PIRSF PIRSF001400 2 422 1.5E-189 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMALA_RS16210 72080853fca61727a50e61faf7e64c81 426 SMART SM01192 139 423 2.3E-227 T 29-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMALA_RS16210 72080853fca61727a50e61faf7e64c81 426 Pfam PF00113 Enolase, C-terminal TIM barrel domain 140 420 1.5E-134 T 29-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMALA_RS16210 72080853fca61727a50e61faf7e64c81 426 Gene3D G3DSA:3.20.20.120 128 425 3.1E-105 T 29-03-2018 IPR029065 Enolase C-terminal domain-like SMALA_RS16210 72080853fca61727a50e61faf7e64c81 426 ProSitePatterns PS00164 Enolase signature. 332 345 - T 29-03-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMALA_RS16210 72080853fca61727a50e61faf7e64c81 426 Pfam PF03952 Enolase, N-terminal domain 4 134 1.6E-55 T 29-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMALA_RS16210 72080853fca61727a50e61faf7e64c81 426 SUPERFAMILY SSF54826 4 138 1.2E-51 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMALA_RS16210 72080853fca61727a50e61faf7e64c81 426 SUPERFAMILY SSF51604 138 422 6.12E-133 T 29-03-2018 IPR029065 Enolase C-terminal domain-like SMALA_RS16210 72080853fca61727a50e61faf7e64c81 426 Hamap MF_00318 Enolase [eno]. 2 409 45.267 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMALA_RS16210 72080853fca61727a50e61faf7e64c81 426 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 423 1.5E-206 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMALA_RS16210 72080853fca61727a50e61faf7e64c81 426 SMART SM01193 4 134 6.8E-87 T 29-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMALA_RS10700 8029052f087cf2c0c60ae4ca1a41e112 447 PRINTS PR00757 Flavin-containing amine oxidase signature 9 28 8.0E-6 T 29-03-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 SMALA_RS10700 8029052f087cf2c0c60ae4ca1a41e112 447 PRINTS PR00757 Flavin-containing amine oxidase signature 401 418 8.0E-6 T 29-03-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 SMALA_RS10700 8029052f087cf2c0c60ae4ca1a41e112 447 Pfam PF01593 Flavin containing amine oxidoreductase 17 420 8.3E-39 T 29-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 SMALA_RS10700 8029052f087cf2c0c60ae4ca1a41e112 447 Gene3D G3DSA:3.50.50.60 8 284 1.9E-22 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS10700 8029052f087cf2c0c60ae4ca1a41e112 447 Gene3D G3DSA:3.50.50.60 285 423 1.2E-7 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS10700 8029052f087cf2c0c60ae4ca1a41e112 447 SUPERFAMILY SSF51905 7 293 1.62E-48 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS10700 8029052f087cf2c0c60ae4ca1a41e112 447 SUPERFAMILY SSF51905 380 422 1.62E-48 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS17240 9a478caa79e1605a12ed256d6a8062d9 228 Pfam PF00805 Pentapeptide repeats (8 copies) 149 187 1.3E-7 T 29-03-2018 IPR001646 Pentapeptide repeat SMALA_RS17240 9a478caa79e1605a12ed256d6a8062d9 228 Gene3D G3DSA:2.160.10.20 125 216 1.5E-12 T 29-03-2018 SMALA_RS17240 9a478caa79e1605a12ed256d6a8062d9 228 Gene3D G3DSA:2.160.10.20 31 124 2.3E-13 T 29-03-2018 SMALA_RS17240 9a478caa79e1605a12ed256d6a8062d9 228 SUPERFAMILY SSF141571 47 208 3.4E-30 T 29-03-2018 SMALA_RS17240 9a478caa79e1605a12ed256d6a8062d9 228 Pfam PF13599 Pentapeptide repeats (9 copies) 64 129 2.3E-10 T 29-03-2018 IPR001646 Pentapeptide repeat SMALA_RS42235 17b787686c1aa64abba0f00a67b07bd1 412 Pfam PF13535 ATP-grasp domain 150 283 1.1E-15 T 29-03-2018 SMALA_RS42235 17b787686c1aa64abba0f00a67b07bd1 412 Gene3D G3DSA:3.30.470.20 117 392 2.0E-37 T 29-03-2018 SMALA_RS42235 17b787686c1aa64abba0f00a67b07bd1 412 SUPERFAMILY SSF56059 112 325 7.07E-32 T 29-03-2018 SMALA_RS42235 17b787686c1aa64abba0f00a67b07bd1 412 Gene3D G3DSA:3.40.50.20 8 116 8.3E-8 T 29-03-2018 SMALA_RS40240 e45819c3154b475976426f2854c75d6e 485 Gene3D G3DSA:1.20.1250.20 264 475 4.1E-21 T 29-03-2018 SMALA_RS40240 e45819c3154b475976426f2854c75d6e 485 SUPERFAMILY SSF103473 9 199 4.45E-52 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS40240 e45819c3154b475976426f2854c75d6e 485 SUPERFAMILY SSF103473 253 459 4.45E-52 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS40240 e45819c3154b475976426f2854c75d6e 485 Pfam PF07690 Major Facilitator Superfamily 17 416 6.0E-37 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS40240 e45819c3154b475976426f2854c75d6e 485 Gene3D G3DSA:1.20.1250.20 11 201 7.7E-25 T 29-03-2018 SMALA_RS10105 f3c17cd6970ecda5c173e7dcf8198c0f 346 SMART SM00382 51 235 5.1E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS10105 f3c17cd6970ecda5c173e7dcf8198c0f 346 SUPERFAMILY SSF52540 10 248 1.67E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS10105 f3c17cd6970ecda5c173e7dcf8198c0f 346 Pfam PF00005 ABC transporter 43 186 1.1E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS10105 f3c17cd6970ecda5c173e7dcf8198c0f 346 ProSitePatterns PS00211 ABC transporters family signature. 158 172 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS10105 f3c17cd6970ecda5c173e7dcf8198c0f 346 Gene3D G3DSA:3.40.50.300 12 278 1.5E-59 T 29-03-2018 SMALA_RS35935 e83267cebf2361dc1299f784a4027df1 572 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 7 169 2.5E-29 T 29-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 SMALA_RS35935 e83267cebf2361dc1299f784a4027df1 572 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 294 471 3.3E-53 T 29-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 SMALA_RS35935 e83267cebf2361dc1299f784a4027df1 572 SUPERFAMILY SSF48179 171 273 5.53E-26 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMALA_RS35935 e83267cebf2361dc1299f784a4027df1 572 SUPERFAMILY SSF48179 474 569 1.79E-26 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMALA_RS35935 e83267cebf2361dc1299f784a4027df1 572 Gene3D G3DSA:3.40.50.720 279 472 8.2E-50 T 29-03-2018 SMALA_RS35935 e83267cebf2361dc1299f784a4027df1 572 Gene3D G3DSA:3.40.50.720 1 170 4.1E-36 T 29-03-2018 SMALA_RS35935 e83267cebf2361dc1299f784a4027df1 572 SUPERFAMILY SSF51735 5 171 1.42E-30 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS35935 e83267cebf2361dc1299f784a4027df1 572 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 172 268 3.4E-25 T 29-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 SMALA_RS35935 e83267cebf2361dc1299f784a4027df1 572 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 474 566 2.0E-27 T 29-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 SMALA_RS35935 e83267cebf2361dc1299f784a4027df1 572 SUPERFAMILY SSF51735 290 471 4.34E-47 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS35935 e83267cebf2361dc1299f784a4027df1 572 Gene3D G3DSA:1.10.1040.10 171 272 3.1E-25 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMALA_RS35935 e83267cebf2361dc1299f784a4027df1 572 Gene3D G3DSA:1.10.1040.10 473 572 9.4E-27 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMALA_RS11240 3ad87c449f7763ef6ae0666a23692b8d 880 SUPERFAMILY SSF81923 4 160 4.22E-43 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 SMALA_RS11240 3ad87c449f7763ef6ae0666a23692b8d 880 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 97 150 2.8E-11 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 SMALA_RS11240 3ad87c449f7763ef6ae0666a23692b8d 880 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 68 1.7E-14 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 SMALA_RS11240 3ad87c449f7763ef6ae0666a23692b8d 880 SMART SM00382 203 348 1.8E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS11240 3ad87c449f7763ef6ae0666a23692b8d 880 SMART SM00382 605 758 2.4E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS11240 3ad87c449f7763ef6ae0666a23692b8d 880 SUPERFAMILY SSF52540 164 553 2.34E-94 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS11240 3ad87c449f7763ef6ae0666a23692b8d 880 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 6 865 0.0 T 29-03-2018 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0016485 SMALA_RS11240 3ad87c449f7763ef6ae0666a23692b8d 880 Gene3D G3DSA:1.10.1780.10 1 156 1.2E-41 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 SMALA_RS11240 3ad87c449f7763ef6ae0666a23692b8d 880 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 654 672 1.4E-42 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 SMALA_RS11240 3ad87c449f7763ef6ae0666a23692b8d 880 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 716 730 1.4E-42 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 SMALA_RS11240 3ad87c449f7763ef6ae0666a23692b8d 880 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 609 627 1.4E-42 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 SMALA_RS11240 3ad87c449f7763ef6ae0666a23692b8d 880 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 683 701 1.4E-42 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 SMALA_RS11240 3ad87c449f7763ef6ae0666a23692b8d 880 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 208 340 2.6E-11 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 SMALA_RS11240 3ad87c449f7763ef6ae0666a23692b8d 880 Gene3D G3DSA:3.40.50.300 162 347 1.4E-24 T 29-03-2018 SMALA_RS11240 3ad87c449f7763ef6ae0666a23692b8d 880 Pfam PF07724 AAA domain (Cdc48 subfamily) 604 770 3.2E-54 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 SMALA_RS11240 3ad87c449f7763ef6ae0666a23692b8d 880 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 299 311 - T 29-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 SMALA_RS11240 3ad87c449f7763ef6ae0666a23692b8d 880 SMART SM01086 776 865 8.7E-33 T 29-03-2018 IPR019489 Clp ATPase, C-terminal SMALA_RS11240 3ad87c449f7763ef6ae0666a23692b8d 880 Gene3D G3DSA:3.40.50.300 560 775 1.6E-50 T 29-03-2018 SMALA_RS11240 3ad87c449f7763ef6ae0666a23692b8d 880 Gene3D G3DSA:1.10.8.60 776 871 1.4E-22 T 29-03-2018 SMALA_RS11240 3ad87c449f7763ef6ae0666a23692b8d 880 Gene3D G3DSA:1.10.8.60 348 555 3.8E-45 T 29-03-2018 SMALA_RS11240 3ad87c449f7763ef6ae0666a23692b8d 880 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 776 856 2.2E-23 T 29-03-2018 IPR019489 Clp ATPase, C-terminal SMALA_RS11240 3ad87c449f7763ef6ae0666a23692b8d 880 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 639 657 - T 29-03-2018 IPR028299 ClpA/B, conserved site 2 SMALA_RS11240 3ad87c449f7763ef6ae0666a23692b8d 880 SUPERFAMILY SSF52540 554 864 3.1E-79 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS16045 c6735c2c9c88b75bc907cea2d0550179 552 TIGRFAM TIGR01228 hutU: urocanate hydratase 6 548 5.1E-271 T 29-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 SMALA_RS16045 c6735c2c9c88b75bc907cea2d0550179 552 Hamap MF_00577 Urocanate hydratase [hutU]. 2 550 49.043 T 29-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 SMALA_RS16045 c6735c2c9c88b75bc907cea2d0550179 552 Gene3D G3DSA:3.40.1770.10 191 548 2.5E-153 T 29-03-2018 SMALA_RS16045 c6735c2c9c88b75bc907cea2d0550179 552 Gene3D G3DSA:3.40.1770.10 5 148 2.0E-28 T 29-03-2018 SMALA_RS16045 c6735c2c9c88b75bc907cea2d0550179 552 Pfam PF01175 Urocanase Rossmann-like domain 136 343 1.4E-82 T 29-03-2018 IPR035085 Urocanase, Rossmann-like domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 SMALA_RS16045 c6735c2c9c88b75bc907cea2d0550179 552 Pfam PF17392 Urocanase C-terminal domain 346 540 2.6E-91 T 29-03-2018 IPR035401 Urocanase, C-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 SMALA_RS16045 c6735c2c9c88b75bc907cea2d0550179 552 Pfam PF17391 Urocanase N-terminal domain 7 133 1.8E-60 T 29-03-2018 IPR035400 Urocanase, N-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 SMALA_RS16045 c6735c2c9c88b75bc907cea2d0550179 552 PIRSF PIRSF001423 1 552 8.4E-278 T 29-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 SMALA_RS16045 c6735c2c9c88b75bc907cea2d0550179 552 SUPERFAMILY SSF111326 4 549 3.66E-247 T 29-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 SMALA_RS16045 c6735c2c9c88b75bc907cea2d0550179 552 ProSitePatterns PS01233 Urocanase signature. 436 451 - T 29-03-2018 IPR023636 Urocanase conserved site GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 SMALA_RS02215 4cacbe3627959f825adf3667c84f7aba 880 SUPERFAMILY SSF56112 202 417 1.26E-34 T 29-03-2018 IPR011009 Protein kinase-like domain SMALA_RS02215 4cacbe3627959f825adf3667c84f7aba 880 SMART SM00220 148 401 2.8E-10 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMALA_RS02215 4cacbe3627959f825adf3667c84f7aba 880 ProSitePatterns PS00109 Tyrosine protein kinases specific active-site signature. 264 276 - T 29-03-2018 IPR008266 Tyrosine-protein kinase, active site GO:0004672|GO:0006468 SMALA_RS02215 4cacbe3627959f825adf3667c84f7aba 880 Pfam PF00069 Protein kinase domain 229 399 3.7E-19 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMALA_RS02215 4cacbe3627959f825adf3667c84f7aba 880 Gene3D G3DSA:1.10.510.10 145 404 1.0E-31 T 29-03-2018 SMALA_RS32920 73c23d2d143c043437232d73d65acb7b 362 SMART SM00382 69 202 2.9E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS32920 73c23d2d143c043437232d73d65acb7b 362 Gene3D G3DSA:1.10.10.10 275 345 6.8E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS32920 73c23d2d143c043437232d73d65acb7b 362 Gene3D G3DSA:3.40.50.300 36 199 1.4E-25 T 29-03-2018 SMALA_RS32920 73c23d2d143c043437232d73d65acb7b 362 SUPERFAMILY SSF46785 275 348 3.74E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS32920 73c23d2d143c043437232d73d65acb7b 362 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 42 344 1.8E-133 T 29-03-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 SMALA_RS32920 73c23d2d143c043437232d73d65acb7b 362 SUPERFAMILY SSF52540 38 268 2.87E-49 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS32920 73c23d2d143c043437232d73d65acb7b 362 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 22 253 1.5E-107 T 29-03-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 SMALA_RS32920 73c23d2d143c043437232d73d65acb7b 362 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 362 159.158 T 29-03-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 SMALA_RS32920 73c23d2d143c043437232d73d65acb7b 362 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 271 344 2.5E-28 T 29-03-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 SMALA_RS32920 73c23d2d143c043437232d73d65acb7b 362 Gene3D G3DSA:1.10.8.60 202 272 3.2E-31 T 29-03-2018 SMALA_RS32920 73c23d2d143c043437232d73d65acb7b 362 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 270 346 2.0E-22 T 29-03-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 SMALA_RS12125 846a2aa447ec0128f8448f7c7c4d4e4b 294 Gene3D G3DSA:3.40.50.720 1 144 5.4E-13 T 29-03-2018 SMALA_RS12125 846a2aa447ec0128f8448f7c7c4d4e4b 294 Pfam PF13460 NAD(P)H-binding 13 186 1.1E-14 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS12125 846a2aa447ec0128f8448f7c7c4d4e4b 294 SUPERFAMILY SSF51735 7 253 2.29E-39 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS12125 846a2aa447ec0128f8448f7c7c4d4e4b 294 Gene3D G3DSA:3.90.25.10 145 275 2.2E-4 T 29-03-2018 SMALA_RS28905 5b3a2b9c91778bbb147a8a8515234380 312 SUPERFAMILY SSF52540 10 152 1.16E-15 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS28905 5b3a2b9c91778bbb147a8a8515234380 312 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 10 289 5.9E-74 T 29-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 SMALA_RS28905 5b3a2b9c91778bbb147a8a8515234380 312 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 10 300 27.348 T 29-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 SMALA_RS28905 5b3a2b9c91778bbb147a8a8515234380 312 Pfam PF01715 IPP transferase 43 285 9.9E-73 T 29-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 SMALA_RS28905 5b3a2b9c91778bbb147a8a8515234380 312 Gene3D G3DSA:1.10.287.890 200 281 1.0E-20 T 29-03-2018 SMALA_RS28905 5b3a2b9c91778bbb147a8a8515234380 312 Gene3D G3DSA:3.40.50.300 8 196 3.4E-58 T 29-03-2018 SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 Gene3D G3DSA:3.40.50.720 5578 5874 7.2E-44 T 29-03-2018 SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 SMART SM00829 5267 5572 1.6E-182 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 14 266 9.0E-78 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1049 1299 1.0E-89 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2536 2787 2.2E-93 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3866 4116 9.1E-93 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 ProSitePatterns PS00012 Phosphopantetheine attachment site. 5898 5913 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 SUPERFAMILY SSF50129 5278 5399 1.1E-29 T 29-03-2018 IPR011032 GroES-like SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 SUPERFAMILY SSF55048 3194 3259 8.63E-13 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 Pfam PF00698 Acyl transferase domain 1586 1865 9.7E-54 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 Pfam PF00698 Acyl transferase domain 4403 4716 2.6E-89 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 Pfam PF00698 Acyl transferase domain 558 876 5.3E-90 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 Pfam PF00698 Acyl transferase domain 3069 3387 4.5E-92 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 Gene3D G3DSA:3.40.50.720 2159 2414 4.2E-53 T 29-03-2018 SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 Gene3D G3DSA:3.40.366.10 1583 1721 8.9E-43 T 29-03-2018 SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 Gene3D G3DSA:3.40.366.10 4401 4534 3.6E-40 T 29-03-2018 SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 Gene3D G3DSA:3.40.366.10 3066 3204 2.8E-44 T 29-03-2018 SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 Gene3D G3DSA:3.40.366.10 556 693 2.3E-42 T 29-03-2018 SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 3070 3368 7.1E-125 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 559 857 7.6E-122 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 4404 4698 8.9E-126 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1586 1878 9.3E-127 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 Gene3D G3DSA:3.40.47.10 6 277 1.7E-80 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 Pfam PF14765 Polyketide synthase dehydratase 3435 3720 2.9E-52 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 Pfam PF14765 Polyketide synthase dehydratase 4766 5045 8.3E-56 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 5287 5342 1.3E-6 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 SMART SM00826 3435 3608 3.2E-84 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 SMART SM00826 4766 4930 1.4E-81 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 SMART SM00823 Phosphopantetheine attachment site 3771 3843 1.7E-33 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 SMART SM00823 Phosphopantetheine attachment site 2444 2516 3.7E-30 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 SMART SM00823 Phosphopantetheine attachment site 5871 5943 5.4E-34 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 SMART SM00823 Phosphopantetheine attachment site 957 1029 2.3E-27 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 Gene3D G3DSA:3.10.129.10 4781 4891 1.4E-6 T 29-03-2018 SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 Gene3D G3DSA:3.10.129.10 3441 3563 7.1E-5 T 29-03-2018 SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 SUPERFAMILY SSF47336 954 1064 6.94E-22 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 SUPERFAMILY SSF53901 1046 1422 4.55E-103 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 Gene3D G3DSA:3.40.366.10 4582 4705 6.7E-32 T 29-03-2018 SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 Gene3D G3DSA:3.40.366.10 3252 3375 5.5E-29 T 29-03-2018 SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 Gene3D G3DSA:3.40.366.10 741 863 4.1E-25 T 29-03-2018 SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 2700 2716 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 SUPERFAMILY SSF52151 1765 1870 2.88E-74 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 SUPERFAMILY SSF52151 1584 1703 2.88E-74 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 4029 4045 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 274 391 2.8E-38 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1307 1425 7.5E-46 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2795 2912 1.9E-44 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 4124 4241 7.1E-43 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 Gene3D G3DSA:1.10.1200.10 3715 3848 6.0E-19 T 29-03-2018 SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 Gene3D G3DSA:1.10.1200.10 2419 2519 1.3E-19 T 29-03-2018 SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 SUPERFAMILY SSF47336 5865 5944 2.22E-22 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 SUPERFAMILY SSF47336 3766 3881 9.68E-22 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 Pfam PF00550 Phosphopantetheine attachment site 5874 5939 1.1E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 Pfam PF00550 Phosphopantetheine attachment site 3776 3839 1.3E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 Pfam PF00550 Phosphopantetheine attachment site 959 1025 1.1E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 Pfam PF00550 Phosphopantetheine attachment site 2446 2512 1.7E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1428 1549 4.1E-12 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 394 520 7.5E-16 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2915 3024 4.9E-13 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 4244 4366 1.5E-14 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 SUPERFAMILY SSF51735 5366 5543 1.09E-35 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 Gene3D G3DSA:3.40.47.10 2530 2799 4.0E-90 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 Gene3D G3DSA:3.40.47.10 3858 4128 3.9E-90 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 Gene3D G3DSA:3.40.47.10 1048 1311 2.2E-86 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 SUPERFAMILY SSF53901 3864 4238 2.39E-106 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2471 2486 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1212 1228 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 Gene3D G3DSA:3.40.47.10 281 448 8.8E-56 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 Gene3D G3DSA:3.40.47.10 1314 1476 2.1E-63 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 Gene3D G3DSA:3.40.47.10 4131 4292 1.2E-61 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 Gene3D G3DSA:3.40.47.10 2802 2963 1.9E-63 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 SUPERFAMILY SSF52151 4590 4689 4.19E-69 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 SUPERFAMILY SSF52151 4402 4526 4.19E-69 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 SUPERFAMILY SSF52151 3260 3359 1.05E-70 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 SUPERFAMILY SSF52151 3066 3196 1.05E-70 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 SUPERFAMILY SSF51735 5581 5777 5.86E-44 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 SUPERFAMILY SSF53901 2534 2911 1.77E-106 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 Pfam PF08659 KR domain 5582 5761 1.6E-56 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 Pfam PF08659 KR domain 2164 2342 5.9E-58 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 SUPERFAMILY SSF55048 4524 4589 4.58E-14 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 SUPERFAMILY SSF55048 1708 1772 1.96E-11 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 SUPERFAMILY SSF55048 683 748 7.72E-13 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 Gene3D G3DSA:1.10.1200.10 5875 6048 1.1E-20 T 29-03-2018 SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 Gene3D G3DSA:1.10.1200.10 951 1047 2.1E-18 T 29-03-2018 SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 Gene3D G3DSA:3.40.366.10 1763 1889 5.7E-29 T 29-03-2018 SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 Pfam PF13602 Zinc-binding dehydrogenase 5442 5572 9.4E-19 T 29-03-2018 SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 SUPERFAMILY SSF47336 2441 2550 1.44E-23 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 Gene3D G3DSA:3.90.180.10 5254 5575 2.2E-67 T 29-03-2018 SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 SUPERFAMILY SSF51735 5052 5243 1.65E-37 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 SUPERFAMILY SSF53901 11 388 3.94E-85 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 SUPERFAMILY SSF52151 556 685 3.4E-68 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 SUPERFAMILY SSF52151 749 848 3.4E-68 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2164 2343 3.2E-54 T 29-03-2018 SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5582 5762 5.5E-54 T 29-03-2018 SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 SMART SM01294 2445 2512 1.4E-5 T 29-03-2018 SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 SMART SM01294 5872 5939 3.4E-5 T 29-03-2018 SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 SMART SM01294 3772 3839 5.0E-5 T 29-03-2018 SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 SMART SM01294 958 1025 8.9E-5 T 29-03-2018 SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 Gene3D G3DSA:3.30.70.250 4535 4581 2.1E-19 T 29-03-2018 SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 Gene3D G3DSA:3.30.70.250 694 740 3.2E-17 T 29-03-2018 SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 Gene3D G3DSA:3.30.70.250 1722 1762 2.8E-18 T 29-03-2018 SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 Gene3D G3DSA:3.30.70.250 3205 3251 1.1E-17 T 29-03-2018 SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 SMART SM00825 Beta-ketoacyl synthase 1051 1478 1.6E-225 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 SMART SM00825 Beta-ketoacyl synthase 16 450 2.9E-187 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 SMART SM00825 Beta-ketoacyl synthase 3868 4294 8.6E-228 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 SMART SM00825 Beta-ketoacyl synthase 2538 2965 9.9E-232 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 SUPERFAMILY SSF51735 1940 2151 7.22E-41 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS01610 202e0e3af51b6ff683cddc313af75ef0 6063 SUPERFAMILY SSF51735 2161 2379 1.08E-47 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS13350 e72e1f1674c49193884266c5dbb91881 881 SUPERFAMILY SSF63737 5 207 1.1E-40 T 29-03-2018 SMALA_RS13350 e72e1f1674c49193884266c5dbb91881 881 TIGRFAM TIGR02412 pepN_strep_liv: aminopeptidase N 5 875 0.0 T 29-03-2018 IPR012778 Peptidase M1, aminopeptidase GO:0004177|GO:0006508 KEGG: 00480+3.4.11.2|MetaCyc: PWY-4061|MetaCyc: PWY-6842|MetaCyc: PWY-7112 SMALA_RS13350 e72e1f1674c49193884266c5dbb91881 881 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 331 343 8.9E-18 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMALA_RS13350 e72e1f1674c49193884266c5dbb91881 881 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 140 155 8.9E-18 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMALA_RS13350 e72e1f1674c49193884266c5dbb91881 881 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 190 205 8.9E-18 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMALA_RS13350 e72e1f1674c49193884266c5dbb91881 881 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 278 288 8.9E-18 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMALA_RS13350 e72e1f1674c49193884266c5dbb91881 881 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 312 327 8.9E-18 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMALA_RS13350 e72e1f1674c49193884266c5dbb91881 881 Pfam PF01433 Peptidase family M1 domain 247 460 2.4E-58 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMALA_RS13350 e72e1f1674c49193884266c5dbb91881 881 Gene3D G3DSA:1.10.390.10 299 464 3.4E-45 T 29-03-2018 SMALA_RS13350 e72e1f1674c49193884266c5dbb91881 881 Pfam PF11838 ERAP1-like C-terminal domain 557 868 8.4E-60 T 29-03-2018 IPR024571 ERAP1-like C-terminal domain SMALA_RS13350 e72e1f1674c49193884266c5dbb91881 881 SUPERFAMILY SSF55486 226 470 8.55E-74 T 29-03-2018 SMALA_RS13350 e72e1f1674c49193884266c5dbb91881 881 Gene3D G3DSA:2.60.40.1730 17 206 2.3E-35 T 29-03-2018 SMALA_RS19095 35e40918d40ad1c7dac05674f151e7fb 508 SUPERFAMILY SSF103473 20 210 2.35E-65 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS19095 35e40918d40ad1c7dac05674f151e7fb 508 SUPERFAMILY SSF103473 471 499 2.35E-65 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS19095 35e40918d40ad1c7dac05674f151e7fb 508 SUPERFAMILY SSF103473 261 433 2.35E-65 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS19095 35e40918d40ad1c7dac05674f151e7fb 508 Gene3D G3DSA:1.20.1250.20 21 213 1.2E-38 T 29-03-2018 SMALA_RS19095 35e40918d40ad1c7dac05674f151e7fb 508 Pfam PF07690 Major Facilitator Superfamily 31 423 8.0E-53 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS19095 35e40918d40ad1c7dac05674f151e7fb 508 Gene3D G3DSA:1.20.1250.20 265 508 1.8E-23 T 29-03-2018 SMALA_RS19095 35e40918d40ad1c7dac05674f151e7fb 508 PRINTS PR01036 Tetracycline resistance protein TetB signature 30 54 6.1E-13 T 29-03-2018 SMALA_RS19095 35e40918d40ad1c7dac05674f151e7fb 508 PRINTS PR01036 Tetracycline resistance protein TetB signature 151 175 6.1E-13 T 29-03-2018 SMALA_RS19095 35e40918d40ad1c7dac05674f151e7fb 508 PRINTS PR01036 Tetracycline resistance protein TetB signature 90 112 6.1E-13 T 29-03-2018 SMALA_RS19095 35e40918d40ad1c7dac05674f151e7fb 508 PRINTS PR01036 Tetracycline resistance protein TetB signature 414 433 6.1E-13 T 29-03-2018 SMALA_RS14210 53baf84a54c3952cf513cd2c5f6275b3 388 SUPERFAMILY SSF47203 235 384 5.15E-50 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMALA_RS14210 53baf84a54c3952cf513cd2c5f6275b3 388 SUPERFAMILY SSF56645 3 249 4.71E-80 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMALA_RS14210 53baf84a54c3952cf513cd2c5f6275b3 388 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 126 138 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 SMALA_RS14210 53baf84a54c3952cf513cd2c5f6275b3 388 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 124 224 6.8E-22 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 SMALA_RS14210 53baf84a54c3952cf513cd2c5f6275b3 388 Gene3D G3DSA:1.20.140.10 225 385 7.0E-54 T 29-03-2018 SMALA_RS14210 53baf84a54c3952cf513cd2c5f6275b3 388 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 120 3.6E-37 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS14210 53baf84a54c3952cf513cd2c5f6275b3 388 Gene3D G3DSA:2.40.110.10 123 224 9.0E-32 T 29-03-2018 SMALA_RS14210 53baf84a54c3952cf513cd2c5f6275b3 388 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 236 384 7.1E-48 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMALA_RS14210 53baf84a54c3952cf513cd2c5f6275b3 388 PIRSF PIRSF016578 4 116 2.6E-4 T 29-03-2018 SMALA_RS14210 53baf84a54c3952cf513cd2c5f6275b3 388 PIRSF PIRSF016578 131 387 6.6E-7 T 29-03-2018 SMALA_RS14210 53baf84a54c3952cf513cd2c5f6275b3 388 Gene3D G3DSA:1.10.540.10 1 122 3.1E-40 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS14210 53baf84a54c3952cf513cd2c5f6275b3 388 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 343 362 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 SMALA_RS35110 e14ffd2f5680fff93aed5e8c73e96d4b 360 ProSitePatterns PS00894 DeoR-type HTH domain signature. 8 42 - T 29-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 SMALA_RS35110 e14ffd2f5680fff93aed5e8c73e96d4b 360 SUPERFAMILY SSF53822 74 358 2.83E-29 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SMALA_RS35110 e14ffd2f5680fff93aed5e8c73e96d4b 360 SMART SM00420 8 60 4.2E-12 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMALA_RS35110 e14ffd2f5680fff93aed5e8c73e96d4b 360 Pfam PF08220 DeoR-like helix-turn-helix domain 8 61 4.6E-13 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMALA_RS35110 e14ffd2f5680fff93aed5e8c73e96d4b 360 Gene3D G3DSA:3.40.50.2300 68 192 7.0E-24 T 29-03-2018 SMALA_RS35110 e14ffd2f5680fff93aed5e8c73e96d4b 360 Gene3D G3DSA:1.10.10.10 3 65 5.8E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS35110 e14ffd2f5680fff93aed5e8c73e96d4b 360 SUPERFAMILY SSF46785 7 61 2.31E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS35110 e14ffd2f5680fff93aed5e8c73e96d4b 360 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 26 40 3.3E-7 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMALA_RS35110 e14ffd2f5680fff93aed5e8c73e96d4b 360 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 40 58 3.3E-7 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMALA_RS35110 e14ffd2f5680fff93aed5e8c73e96d4b 360 Pfam PF13377 Periplasmic binding protein-like domain 188 356 5.3E-24 T 29-03-2018 SMALA_RS35110 e14ffd2f5680fff93aed5e8c73e96d4b 360 Gene3D G3DSA:3.40.50.2300 193 334 1.0E-22 T 29-03-2018 SMALA_RS23915 fd3fa6824263ae38cb5ce0487c20fcb1 164 Gene3D G3DSA:3.90.960.10 4 163 3.2E-41 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 SMALA_RS23915 fd3fa6824263ae38cb5ce0487c20fcb1 164 Pfam PF04073 Aminoacyl-tRNA editing domain 33 149 4.8E-28 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 SMALA_RS23915 fd3fa6824263ae38cb5ce0487c20fcb1 164 SUPERFAMILY SSF55826 15 160 1.96E-37 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 SMALA_RS22485 46994fbc303d6714d0a3e955035e11a6 706 Gene3D G3DSA:1.10.150.20 144 196 0.024 T 29-03-2018 SMALA_RS22485 46994fbc303d6714d0a3e955035e11a6 706 Gene3D G3DSA:1.25.10.10 402 704 3.7E-6 T 29-03-2018 IPR011989 Armadillo-like helical SMALA_RS31805 9a5bb1e429f74ad3ae044bd161915a82 549 Gene3D G3DSA:3.90.76.10 77 169 2.0E-22 T 29-03-2018 SMALA_RS31805 9a5bb1e429f74ad3ae044bd161915a82 549 PIRSF PIRSF002741 7 545 1.8E-71 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 SMALA_RS31805 9a5bb1e429f74ad3ae044bd161915a82 549 Gene3D G3DSA:3.40.190.10 170 305 1.0E-27 T 29-03-2018 SMALA_RS31805 9a5bb1e429f74ad3ae044bd161915a82 549 SUPERFAMILY SSF53850 51 539 4.71E-92 T 29-03-2018 SMALA_RS31805 9a5bb1e429f74ad3ae044bd161915a82 549 Gene3D G3DSA:3.10.105.10 306 516 1.3E-38 T 29-03-2018 SMALA_RS31805 9a5bb1e429f74ad3ae044bd161915a82 549 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 97 468 7.5E-61 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain SMALA_RS28255 0a85ba9d4d396a391bddc7143911a222 357 Gene3D G3DSA:3.40.190.10 156 354 2.8E-28 T 29-03-2018 SMALA_RS28255 0a85ba9d4d396a391bddc7143911a222 357 Gene3D G3DSA:3.40.190.10 25 155 2.7E-14 T 29-03-2018 SMALA_RS28255 0a85ba9d4d396a391bddc7143911a222 357 SUPERFAMILY SSF53850 36 355 3.78E-50 T 29-03-2018 SMALA_RS28255 0a85ba9d4d396a391bddc7143911a222 357 TIGRFAM TIGR01254 sfuA: ABC transporter periplasmic binding protein, thiB subfamily 36 352 3.0E-70 T 29-03-2018 IPR005948 Thiamine/thiamin pyrophosphate-binding periplasmic protein, ABC transporter GO:0015888|GO:0030288|GO:0030975 SMALA_RS28255 0a85ba9d4d396a391bddc7143911a222 357 Pfam PF13343 Bacterial extracellular solute-binding protein 87 320 2.2E-21 T 29-03-2018 SMALA_RS41565 b96b422be8f1ba6c9638dd706ba8d4dd 328 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 91 321 2.7E-57 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 SMALA_RS41565 b96b422be8f1ba6c9638dd706ba8d4dd 328 Gene3D G3DSA:3.90.850.10 41 328 6.6E-65 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 SMALA_RS41565 b96b422be8f1ba6c9638dd706ba8d4dd 328 SUPERFAMILY SSF56529 84 324 9.42E-59 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 SMALA_RS27305 70d75b0c641264c6c92977c9de1fcee8 749 Gene3D G3DSA:2.60.40.1180 657 749 5.5E-31 T 29-03-2018 SMALA_RS27305 70d75b0c641264c6c92977c9de1fcee8 749 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 650 748 2.2E-17 T 29-03-2018 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 SMALA_RS27305 70d75b0c641264c6c92977c9de1fcee8 749 PIRSF PIRSF000463 28 749 2.9E-287 T 29-03-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077 SMALA_RS27305 70d75b0c641264c6c92977c9de1fcee8 749 SUPERFAMILY SSF51445 196 639 6.72E-108 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS27305 70d75b0c641264c6c92977c9de1fcee8 749 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 141 223 1.5E-18 T 29-03-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077 SMALA_RS27305 70d75b0c641264c6c92977c9de1fcee8 749 SUPERFAMILY SSF81296 35 130 2.8E-19 T 29-03-2018 IPR014756 Immunoglobulin E-set SMALA_RS27305 70d75b0c641264c6c92977c9de1fcee8 749 TIGRFAM TIGR01515 branching_enzym: 1,4-alpha-glucan branching enzyme 125 747 5.1E-292 T 29-03-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077 SMALA_RS27305 70d75b0c641264c6c92977c9de1fcee8 749 SUPERFAMILY SSF51011 645 748 1.51E-29 T 29-03-2018 SMALA_RS27305 70d75b0c641264c6c92977c9de1fcee8 749 Hamap MF_00685 1,4-alpha-glucan branching enzyme GlgB [glgB]. 117 749 43.073 T 29-03-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077 SMALA_RS27305 70d75b0c641264c6c92977c9de1fcee8 749 Pfam PF00128 Alpha amylase, catalytic domain 283 355 5.2E-9 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SMALA_RS27305 70d75b0c641264c6c92977c9de1fcee8 749 Gene3D G3DSA:3.20.20.80 261 656 5.5E-76 T 29-03-2018 SMALA_RS27305 70d75b0c641264c6c92977c9de1fcee8 749 Gene3D G3DSA:2.60.40.10 24 120 2.5E-13 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS27305 70d75b0c641264c6c92977c9de1fcee8 749 Gene3D G3DSA:2.60.40.10 121 238 4.0E-30 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS27305 70d75b0c641264c6c92977c9de1fcee8 749 SMART SM00642 266 626 8.3E-8 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SMALA_RS08230 5de05b0953370f741413c96c5faf15fe 481 Gene3D G3DSA:1.10.40.30 407 474 4.8E-20 T 29-03-2018 SMALA_RS08230 5de05b0953370f741413c96c5faf15fe 481 PRINTS PR00149 Fumarate lyase superfamily signature 115 133 2.7E-16 T 29-03-2018 IPR000362 Fumarate lyase family SMALA_RS08230 5de05b0953370f741413c96c5faf15fe 481 PRINTS PR00149 Fumarate lyase superfamily signature 160 178 2.7E-16 T 29-03-2018 IPR000362 Fumarate lyase family SMALA_RS08230 5de05b0953370f741413c96c5faf15fe 481 PRINTS PR00149 Fumarate lyase superfamily signature 262 289 2.7E-16 T 29-03-2018 IPR000362 Fumarate lyase family SMALA_RS08230 5de05b0953370f741413c96c5faf15fe 481 PRINTS PR00149 Fumarate lyase superfamily signature 307 323 2.7E-16 T 29-03-2018 IPR000362 Fumarate lyase family SMALA_RS08230 5de05b0953370f741413c96c5faf15fe 481 Pfam PF10397 Adenylosuccinate lyase C-terminus 396 473 1.7E-13 T 29-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SMALA_RS08230 5de05b0953370f741413c96c5faf15fe 481 SMART SM00998 395 474 1.2E-14 T 29-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SMALA_RS08230 5de05b0953370f741413c96c5faf15fe 481 SUPERFAMILY SSF48557 32 474 2.67E-91 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 SMALA_RS08230 5de05b0953370f741413c96c5faf15fe 481 Gene3D G3DSA:1.20.200.10 120 406 3.2E-86 T 29-03-2018 SMALA_RS08230 5de05b0953370f741413c96c5faf15fe 481 TIGRFAM TIGR02426 protocat_pcaB: 3-carboxy-cis,cis-muconate cycloisomerase 27 380 4.4E-108 T 29-03-2018 IPR012789 3-carboxy-cis,cis-muconate cycloisomerase GO:0019619|GO:0047472 KEGG: 00362+5.5.1.2 SMALA_RS08230 5de05b0953370f741413c96c5faf15fe 481 Gene3D G3DSA:1.10.275.10 14 119 1.2E-14 T 29-03-2018 IPR024083 Fumarase/histidase, N-terminal SMALA_RS08230 5de05b0953370f741413c96c5faf15fe 481 Pfam PF00206 Lyase 46 330 1.1E-36 T 29-03-2018 IPR022761 Fumarate lyase, N-terminal SMALA_RS13145 191b916eb356208d676550a45e5bc640 640 Pfam PF04055 Radical SAM superfamily 268 433 6.2E-16 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 SMALA_RS13145 191b916eb356208d676550a45e5bc640 640 SMART SM00729 264 487 8.4E-31 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 SMALA_RS13145 191b916eb356208d676550a45e5bc640 640 Gene3D G3DSA:3.20.20.70 154 576 1.9E-36 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS13145 191b916eb356208d676550a45e5bc640 640 SUPERFAMILY SSF102114 232 635 3.53E-52 T 29-03-2018 SMALA_RS13145 191b916eb356208d676550a45e5bc640 640 TIGRFAM TIGR03960 rSAM_fuse_unch: radical SAM family uncharacterized protein 12 618 1.1E-212 T 29-03-2018 IPR023862 Conserved hypothetical protein CHP03960, radical SAM SMALA_RS24435 852888ae05bdda26a5fb277ea7f2a011 617 Pfam PF17297 Phosphoenolpyruvate carboxykinase N-terminal domain 24 253 9.7E-99 T 29-03-2018 IPR035078 Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 SMALA_RS24435 852888ae05bdda26a5fb277ea7f2a011 617 Pfam PF00821 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain 257 616 6.2E-173 T 29-03-2018 IPR035077 Phosphoenolpyruvate carboxykinase, GTP-utilising, C-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 SMALA_RS24435 852888ae05bdda26a5fb277ea7f2a011 617 Gene3D G3DSA:3.40.449.10 7 256 4.1E-114 T 29-03-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 SMALA_RS24435 852888ae05bdda26a5fb277ea7f2a011 617 Hamap MF_00452 Phosphoenolpyruvate carboxykinase [GTP] [pckG]. 12 617 52.036 T 29-03-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 SMALA_RS24435 852888ae05bdda26a5fb277ea7f2a011 617 PIRSF PIRSF001348 4 617 4.9E-277 T 29-03-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 SMALA_RS24435 852888ae05bdda26a5fb277ea7f2a011 617 SUPERFAMILY SSF68923 12 256 2.82E-96 T 29-03-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 SMALA_RS24435 852888ae05bdda26a5fb277ea7f2a011 617 SUPERFAMILY SSF53795 257 616 5.72E-160 T 29-03-2018 SMALA_RS24435 852888ae05bdda26a5fb277ea7f2a011 617 ProSitePatterns PS00505 Phosphoenolpyruvate carboxykinase (GTP) signature. 281 289 - T 29-03-2018 IPR018091 Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site GO:0004613 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 SMALA_RS24435 852888ae05bdda26a5fb277ea7f2a011 617 Gene3D G3DSA:3.90.228.20 257 328 2.4E-21 T 29-03-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 SMALA_RS24435 852888ae05bdda26a5fb277ea7f2a011 617 Gene3D G3DSA:3.90.228.20 336 617 9.1E-128 T 29-03-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 SMALA_RS08045 b5df49d2c1a47dca4d3e38895ef4eacd 633 Pfam PF13506 Glycosyl transferase family 21 230 398 7.4E-18 T 29-03-2018 IPR025993 Ceramide glucosyltransferase GO:0016757 KEGG: 00600+2.4.1.80|MetaCyc: PWY-5129|MetaCyc: PWY-7836|MetaCyc: PWY-7838|MetaCyc: PWY-7839|MetaCyc: PWY-7841|Reactome: R-HSA-1660662 SMALA_RS08045 b5df49d2c1a47dca4d3e38895ef4eacd 633 SUPERFAMILY SSF53448 171 430 4.28E-36 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS08045 b5df49d2c1a47dca4d3e38895ef4eacd 633 Gene3D G3DSA:3.90.550.10 163 411 2.2E-37 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS00225 210a5eaa08779a8317619545103b1ff6 274 PIRSF PIRSF006241 1 273 9.4E-92 T 29-03-2018 IPR026040 Hydroxypyruvate isomerase-like KEGG: 00630+5.3.1.22 SMALA_RS00225 210a5eaa08779a8317619545103b1ff6 274 SUPERFAMILY SSF51658 1 269 2.49E-81 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SMALA_RS00225 210a5eaa08779a8317619545103b1ff6 274 Pfam PF01261 Xylose isomerase-like TIM barrel 21 230 2.7E-34 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SMALA_RS00225 210a5eaa08779a8317619545103b1ff6 274 Gene3D G3DSA:3.20.20.150 1 272 9.6E-55 T 29-03-2018 SMALA_RS05030 42b4f85691acc8297bd0a9569faf3709 251 SUPERFAMILY SSF52540 20 217 2.3E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS05030 42b4f85691acc8297bd0a9569faf3709 251 Pfam PF00005 ABC transporter 35 163 7.8E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS05030 42b4f85691acc8297bd0a9569faf3709 251 SMART SM00382 44 213 6.2E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS05030 42b4f85691acc8297bd0a9569faf3709 251 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS05030 42b4f85691acc8297bd0a9569faf3709 251 Gene3D G3DSA:3.40.50.300 16 237 3.7E-53 T 29-03-2018 SMALA_RS30380 095f3fccdfa8e6f6d7f37e8be58a073b 127 Gene3D G3DSA:2.30.130.30 15 123 4.7E-23 T 29-03-2018 SMALA_RS30380 095f3fccdfa8e6f6d7f37e8be58a073b 127 Pfam PF04266 ASCH domain 19 123 7.4E-9 T 29-03-2018 IPR007374 ASCH domain SMALA_RS30380 095f3fccdfa8e6f6d7f37e8be58a073b 127 SUPERFAMILY SSF88697 16 123 9.07E-18 T 29-03-2018 IPR015947 PUA-like domain SMALA_RS19180 5ffab9e44c43047325537f89ed29b15a 553 SUPERFAMILY SSF56801 11 542 1.15E-137 T 29-03-2018 SMALA_RS19180 5ffab9e44c43047325537f89ed29b15a 553 Gene3D G3DSA:3.40.50.980 190 349 2.8E-44 T 29-03-2018 SMALA_RS19180 5ffab9e44c43047325537f89ed29b15a 553 Gene3D G3DSA:3.30.300.30 441 543 1.4E-27 T 29-03-2018 SMALA_RS19180 5ffab9e44c43047325537f89ed29b15a 553 Pfam PF00501 AMP-binding enzyme 25 446 1.8E-86 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS19180 5ffab9e44c43047325537f89ed29b15a 553 Gene3D G3DSA:2.30.38.10 360 440 7.5E-16 T 29-03-2018 SMALA_RS19180 5ffab9e44c43047325537f89ed29b15a 553 Pfam PF13193 AMP-binding enzyme C-terminal domain 455 530 5.0E-17 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS19180 5ffab9e44c43047325537f89ed29b15a 553 Gene3D G3DSA:3.40.50.980 43 189 9.1E-32 T 29-03-2018 SMALA_RS19180 5ffab9e44c43047325537f89ed29b15a 553 ProSitePatterns PS00455 Putative AMP-binding domain signature. 185 196 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS31970 42845fe5b58f1a7f0259ea7832a9e1a7 1246 SMART SM00560 632 766 7.5E-16 T 29-03-2018 IPR006558 LamG-like jellyroll fold SMALA_RS31970 42845fe5b58f1a7f0259ea7832a9e1a7 1246 SUPERFAMILY SSF49785 34 232 2.98E-53 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS31970 42845fe5b58f1a7f0259ea7832a9e1a7 1246 Gene3D G3DSA:2.60.120.260 22 232 8.8E-53 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS31970 42845fe5b58f1a7f0259ea7832a9e1a7 1246 SUPERFAMILY SSF49303 234 341 1.67E-21 T 29-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 SMALA_RS31970 42845fe5b58f1a7f0259ea7832a9e1a7 1246 SUPERFAMILY SSF74650 945 1233 2.98E-62 T 29-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 SMALA_RS31970 42845fe5b58f1a7f0259ea7832a9e1a7 1246 Gene3D G3DSA:3.20.20.80 343 615 3.3E-53 T 29-03-2018 SMALA_RS31970 42845fe5b58f1a7f0259ea7832a9e1a7 1246 SMART SM01038 956 1231 1.7E-72 T 29-03-2018 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 SMALA_RS31970 42845fe5b58f1a7f0259ea7832a9e1a7 1246 Pfam PF16353 Domain of unknown function(DUF4981) 842 928 1.4E-20 T 29-03-2018 IPR032312 Beta-galactosidase, domain 4 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 SMALA_RS31970 42845fe5b58f1a7f0259ea7832a9e1a7 1246 Gene3D G3DSA:2.60.40.10 825 936 3.6E-24 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS31970 42845fe5b58f1a7f0259ea7832a9e1a7 1246 SUPERFAMILY SSF49303 823 931 3.69E-24 T 29-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 SMALA_RS31970 42845fe5b58f1a7f0259ea7832a9e1a7 1246 Pfam PF02929 Beta galactosidase small chain 959 1230 8.1E-59 T 29-03-2018 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 SMALA_RS31970 42845fe5b58f1a7f0259ea7832a9e1a7 1246 SUPERFAMILY SSF51445 343 579 5.11E-71 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS31970 42845fe5b58f1a7f0259ea7832a9e1a7 1246 SUPERFAMILY SSF49899 581 767 1.13E-26 T 29-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain SMALA_RS31970 42845fe5b58f1a7f0259ea7832a9e1a7 1246 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 62 232 3.1E-45 T 29-03-2018 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 SMALA_RS31970 42845fe5b58f1a7f0259ea7832a9e1a7 1246 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 343 575 1.6E-70 T 29-03-2018 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 SMALA_RS31970 42845fe5b58f1a7f0259ea7832a9e1a7 1246 PRINTS PR00132 Glycosyl hydrolase family 2 signature 159 174 1.2E-30 T 29-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 SMALA_RS31970 42845fe5b58f1a7f0259ea7832a9e1a7 1246 PRINTS PR00132 Glycosyl hydrolase family 2 signature 457 472 1.2E-30 T 29-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 SMALA_RS31970 42845fe5b58f1a7f0259ea7832a9e1a7 1246 PRINTS PR00132 Glycosyl hydrolase family 2 signature 383 401 1.2E-30 T 29-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 SMALA_RS31970 42845fe5b58f1a7f0259ea7832a9e1a7 1246 PRINTS PR00132 Glycosyl hydrolase family 2 signature 352 366 1.2E-30 T 29-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 SMALA_RS31970 42845fe5b58f1a7f0259ea7832a9e1a7 1246 PRINTS PR00132 Glycosyl hydrolase family 2 signature 530 545 1.2E-30 T 29-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 SMALA_RS31970 42845fe5b58f1a7f0259ea7832a9e1a7 1246 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 617 765 3.7E-19 T 29-03-2018 SMALA_RS31970 42845fe5b58f1a7f0259ea7832a9e1a7 1246 Pfam PF00703 Glycosyl hydrolases family 2 235 341 4.9E-14 T 29-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 SMALA_RS31970 42845fe5b58f1a7f0259ea7832a9e1a7 1246 Gene3D G3DSA:2.70.98.10 939 1233 2.4E-80 T 29-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 SMALA_RS31970 42845fe5b58f1a7f0259ea7832a9e1a7 1246 Gene3D G3DSA:2.60.40.10 233 341 2.4E-21 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS31970 42845fe5b58f1a7f0259ea7832a9e1a7 1246 Gene3D G3DSA:2.60.120.200 616 810 8.4E-24 T 29-03-2018 SMALA_RS06975 d8d6ad14eec63b2855146ff209b84599 198 SUPERFAMILY SSF46689 6 81 2.87E-7 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS06975 d8d6ad14eec63b2855146ff209b84599 198 Gene3D G3DSA:1.10.260.40 43 69 1.6E-4 T 29-03-2018 SMALA_RS06975 d8d6ad14eec63b2855146ff209b84599 198 Gene3D G3DSA:1.10.10.60 4 42 1.8E-6 T 29-03-2018 SMALA_RS06975 d8d6ad14eec63b2855146ff209b84599 198 Gene3D G3DSA:1.10.357.10 70 185 1.6E-4 T 29-03-2018 SMALA_RS27670 4445c858cb44b06ff6df672702cdc319 501 Gene3D G3DSA:1.10.10.410 437 498 1.8E-15 T 29-03-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal SMALA_RS27670 4445c858cb44b06ff6df672702cdc319 501 Pfam PF02934 GatB/GatE catalytic domain 19 312 4.8E-103 T 29-03-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 SMALA_RS27670 4445c858cb44b06ff6df672702cdc319 501 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 15 498 35.585 T 29-03-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 SMALA_RS27670 4445c858cb44b06ff6df672702cdc319 501 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 16 497 7.1E-140 T 29-03-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 SMALA_RS27670 4445c858cb44b06ff6df672702cdc319 501 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 163 177 - T 29-03-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 SMALA_RS27670 4445c858cb44b06ff6df672702cdc319 501 SUPERFAMILY SSF89095 353 497 3.14E-24 T 29-03-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 SMALA_RS27670 4445c858cb44b06ff6df672702cdc319 501 Pfam PF02637 GatB domain 352 497 3.3E-39 T 29-03-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 SMALA_RS27670 4445c858cb44b06ff6df672702cdc319 501 SMART SM00845 350 497 1.3E-56 T 29-03-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 SMALA_RS27670 4445c858cb44b06ff6df672702cdc319 501 SUPERFAMILY SSF55931 18 319 1.57E-111 T 29-03-2018 SMALA_RS35945 caf74b342a01ae49148de0ed33dd002e 290 Gene3D G3DSA:3.90.550.10 1 290 1.9E-63 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS35945 caf74b342a01ae49148de0ed33dd002e 290 SUPERFAMILY SSF53448 1 285 4.96E-83 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS35945 caf74b342a01ae49148de0ed33dd002e 290 Pfam PF00483 Nucleotidyl transferase 2 235 4.4E-60 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 SMALA_RS35945 caf74b342a01ae49148de0ed33dd002e 290 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 2 286 6.8E-133 T 29-03-2018 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|KEGG: 00525+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 SMALA_RS31020 f041dea66d9158fa53b192a129c6e349 601 Gene3D G3DSA:3.40.50.1220 195 350 5.2E-33 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain SMALA_RS31020 f041dea66d9158fa53b192a129c6e349 601 Gene3D G3DSA:3.40.50.970 1 185 6.7E-48 T 29-03-2018 SMALA_RS31020 f041dea66d9158fa53b192a129c6e349 601 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 388 542 1.3E-29 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 SMALA_RS31020 f041dea66d9158fa53b192a129c6e349 601 Gene3D G3DSA:3.40.50.970 351 564 4.3E-41 T 29-03-2018 SMALA_RS31020 f041dea66d9158fa53b192a129c6e349 601 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 425 444 - T 29-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 SMALA_RS31020 f041dea66d9158fa53b192a129c6e349 601 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 198 327 2.9E-25 T 29-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 SMALA_RS31020 f041dea66d9158fa53b192a129c6e349 601 SUPERFAMILY SSF52467 192 358 1.64E-39 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain SMALA_RS31020 f041dea66d9158fa53b192a129c6e349 601 SUPERFAMILY SSF52518 364 562 9.65E-53 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold SMALA_RS31020 f041dea66d9158fa53b192a129c6e349 601 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 3 171 4.5E-47 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 SMALA_RS31020 f041dea66d9158fa53b192a129c6e349 601 SUPERFAMILY SSF52518 1 181 8.84E-49 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold SMALA_RS42025 1433f51fcf8bd5c3b8f3d9001ade4d72 906 SUPERFAMILY SSF46894 839 898 1.05E-15 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS42025 1433f51fcf8bd5c3b8f3d9001ade4d72 906 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 846 860 1.5E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS42025 1433f51fcf8bd5c3b8f3d9001ade4d72 906 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 860 876 1.5E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS42025 1433f51fcf8bd5c3b8f3d9001ade4d72 906 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 876 888 1.5E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS42025 1433f51fcf8bd5c3b8f3d9001ade4d72 906 SUPERFAMILY SSF52540 110 242 6.58E-9 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS42025 1433f51fcf8bd5c3b8f3d9001ade4d72 906 SUPERFAMILY SSF52540 12 83 6.58E-9 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS42025 1433f51fcf8bd5c3b8f3d9001ade4d72 906 SMART SM00421 843 900 3.1E-20 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS42025 1433f51fcf8bd5c3b8f3d9001ade4d72 906 Gene3D G3DSA:3.40.50.300 12 176 2.7E-11 T 29-03-2018 SMALA_RS42025 1433f51fcf8bd5c3b8f3d9001ade4d72 906 ProSitePatterns PS00622 LuxR-type HTH domain signature. 860 887 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS42025 1433f51fcf8bd5c3b8f3d9001ade4d72 906 Pfam PF00196 Bacterial regulatory proteins, luxR family 845 896 4.7E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS42025 1433f51fcf8bd5c3b8f3d9001ade4d72 906 Gene3D G3DSA:1.25.40.10 224 591 6.7E-4 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS42025 1433f51fcf8bd5c3b8f3d9001ade4d72 906 Gene3D G3DSA:1.25.40.10 592 827 3.2E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS42025 1433f51fcf8bd5c3b8f3d9001ade4d72 906 Pfam PF13191 AAA ATPase domain 11 157 1.4E-18 T 29-03-2018 SMALA_RS42025 1433f51fcf8bd5c3b8f3d9001ade4d72 906 Gene3D G3DSA:1.10.10.10 838 904 3.3E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS38530 e6a2450645fd150b0b0ecc29731a3f5e 370 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 34 112 1.2E-5 T 29-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain SMALA_RS38530 e6a2450645fd150b0b0ecc29731a3f5e 370 SMART SM00922 130 237 6.7E-18 T 29-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal SMALA_RS38530 e6a2450645fd150b0b0ecc29731a3f5e 370 Pfam PF13378 Enolase C-terminal domain-like 136 362 2.1E-52 T 29-03-2018 IPR029065 Enolase C-terminal domain-like SMALA_RS38530 e6a2450645fd150b0b0ecc29731a3f5e 370 Gene3D G3DSA:3.20.20.120 116 360 3.1E-50 T 29-03-2018 IPR029065 Enolase C-terminal domain-like SMALA_RS38530 e6a2450645fd150b0b0ecc29731a3f5e 370 SUPERFAMILY SSF54826 1 112 3.89E-19 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMALA_RS38530 e6a2450645fd150b0b0ecc29731a3f5e 370 SUPERFAMILY SSF51604 100 369 1.83E-57 T 29-03-2018 IPR029065 Enolase C-terminal domain-like SMALA_RS38530 e6a2450645fd150b0b0ecc29731a3f5e 370 Gene3D G3DSA:3.30.390.10 1 115 2.9E-23 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMALA_RS24315 7f74a121205b01bdcb763d8d343a3c34 393 SUPERFAMILY SSF47413 4 69 7.78E-15 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS24315 7f74a121205b01bdcb763d8d343a3c34 393 Gene3D G3DSA:1.10.260.40 1 80 8.3E-18 T 29-03-2018 SMALA_RS24315 7f74a121205b01bdcb763d8d343a3c34 393 SMART SM00530 8 64 4.2E-13 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS24315 7f74a121205b01bdcb763d8d343a3c34 393 Pfam PF13560 Helix-turn-helix domain 6 60 3.2E-13 T 29-03-2018 SMALA_RS24315 7f74a121205b01bdcb763d8d343a3c34 393 Gene3D G3DSA:1.25.40.10 108 389 5.3E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS39900 1841a09905a2e52a625d50a83a6b0147 676 ProSitePatterns PS00211 ABC transporters family signature. 587 601 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS39900 1841a09905a2e52a625d50a83a6b0147 676 Gene3D G3DSA:3.40.50.300 456 673 8.7E-48 T 29-03-2018 SMALA_RS39900 1841a09905a2e52a625d50a83a6b0147 676 Gene3D G3DSA:3.40.50.300 227 438 3.2E-36 T 29-03-2018 SMALA_RS39900 1841a09905a2e52a625d50a83a6b0147 676 SUPERFAMILY SSF52540 447 671 1.07E-47 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS39900 1841a09905a2e52a625d50a83a6b0147 676 SMART SM00382 257 431 3.2E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS39900 1841a09905a2e52a625d50a83a6b0147 676 SMART SM00382 486 665 1.5E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS39900 1841a09905a2e52a625d50a83a6b0147 676 ProSitePatterns PS00211 ABC transporters family signature. 354 368 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS39900 1841a09905a2e52a625d50a83a6b0147 676 SUPERFAMILY SSF52540 225 429 3.03E-37 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS39900 1841a09905a2e52a625d50a83a6b0147 676 Pfam PF00005 ABC transporter 477 614 8.2E-22 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS39900 1841a09905a2e52a625d50a83a6b0147 676 Pfam PF00005 ABC transporter 251 382 3.9E-18 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS32465 31f26fe79f3f4322d5fb027c4048daaa 324 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 63 1.1E-15 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS32465 31f26fe79f3f4322d5fb027c4048daaa 324 Pfam PF03466 LysR substrate binding domain 91 300 5.2E-41 T 29-03-2018 IPR005119 LysR, substrate-binding SMALA_RS32465 31f26fe79f3f4322d5fb027c4048daaa 324 Gene3D G3DSA:1.10.10.10 2 88 8.1E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS32465 31f26fe79f3f4322d5fb027c4048daaa 324 SUPERFAMILY SSF53850 94 304 6.27E-38 T 29-03-2018 SMALA_RS32465 31f26fe79f3f4322d5fb027c4048daaa 324 Gene3D G3DSA:3.40.190.10 89 185 2.5E-20 T 29-03-2018 SMALA_RS32465 31f26fe79f3f4322d5fb027c4048daaa 324 SUPERFAMILY SSF46785 2 112 2.58E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS32465 31f26fe79f3f4322d5fb027c4048daaa 324 Gene3D G3DSA:3.40.190.10 186 273 8.4E-19 T 29-03-2018 SMALA_RS13710 f1d4c995f2d888755f337f86a8247f30 1012 Pfam PF14028 Lantibiotic biosynthesis dehydratase C-term 747 1000 7.2E-34 T 29-03-2018 IPR023809 Thiopeptide-type bacteriocin biosynthesis domain SMALA_RS13710 f1d4c995f2d888755f337f86a8247f30 1012 Pfam PF04738 Lantibiotic dehydratase, C terminus 48 683 9.3E-189 T 29-03-2018 IPR006827 Lantibiotic dehydratase, C-terminal SMALA_RS13710 f1d4c995f2d888755f337f86a8247f30 1012 TIGRFAM TIGR03891 thiopep_ocin: thiopeptide-type bacteriocin biosynthesis domain 747 999 6.9E-59 T 29-03-2018 IPR023809 Thiopeptide-type bacteriocin biosynthesis domain SMALA_RS17035 e55b3016b702fa8054e83078451137f9 89 SUPERFAMILY SSF48600 15 74 1.1E-11 T 29-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 SMALA_RS17035 e55b3016b702fa8054e83078451137f9 89 SMART SM00830 18 86 1.9E-5 T 29-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 SMALA_RS17035 e55b3016b702fa8054e83078451137f9 89 Gene3D G3DSA:1.20.59.10 1 88 2.0E-14 T 29-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 SMALA_RS17035 e55b3016b702fa8054e83078451137f9 89 TIGRFAM TIGR01808 CM_M_hiGC-arch: chorismate mutase 16 87 3.7E-17 T 29-03-2018 IPR010958 Chorismate mutase, high GC Gram-positive bacteria/archaeal SMALA_RS17035 e55b3016b702fa8054e83078451137f9 89 Pfam PF01817 Chorismate mutase type II 18 71 1.7E-9 T 29-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 SMALA_RS39785 abee28f0ad3cf44eb94d714ab4972fbe 331 Pfam PF13407 Periplasmic binding protein domain 45 299 3.6E-62 T 29-03-2018 IPR025997 Periplasmic binding protein SMALA_RS39785 abee28f0ad3cf44eb94d714ab4972fbe 331 SUPERFAMILY SSF53822 43 319 5.03E-79 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SMALA_RS39785 abee28f0ad3cf44eb94d714ab4972fbe 331 Gene3D G3DSA:3.40.50.2300 38 156 6.4E-26 T 29-03-2018 SMALA_RS39785 abee28f0ad3cf44eb94d714ab4972fbe 331 Gene3D G3DSA:3.40.50.2300 157 312 1.3E-35 T 29-03-2018 SMALA_RS36125 0000d9924324b3143ea0771ae496af05 344 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 194 335 2.2E-27 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMALA_RS36125 0000d9924324b3143ea0771ae496af05 344 Gene3D G3DSA:1.20.140.10 179 338 6.2E-31 T 29-03-2018 SMALA_RS36125 0000d9924324b3143ea0771ae496af05 344 Gene3D G3DSA:1.10.540.10 1 124 2.5E-13 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS36125 0000d9924324b3143ea0771ae496af05 344 SUPERFAMILY SSF56645 1 137 3.53E-11 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMALA_RS36125 0000d9924324b3143ea0771ae496af05 344 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 26 122 6.2E-9 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS36125 0000d9924324b3143ea0771ae496af05 344 SUPERFAMILY SSF47203 195 334 5.8E-34 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMALA_RS30920 875a36fe410624e2de198150da7812c0 848 Gene3D G3DSA:1.20.1250.20 305 559 1.6E-31 T 29-03-2018 SMALA_RS30920 875a36fe410624e2de198150da7812c0 848 Gene3D G3DSA:1.20.1250.20 62 253 1.5E-36 T 29-03-2018 SMALA_RS30920 875a36fe410624e2de198150da7812c0 848 PRINTS PR01036 Tetracycline resistance protein TetB signature 190 214 6.4E-5 T 29-03-2018 SMALA_RS30920 875a36fe410624e2de198150da7812c0 848 PRINTS PR01036 Tetracycline resistance protein TetB signature 160 180 6.4E-5 T 29-03-2018 SMALA_RS30920 875a36fe410624e2de198150da7812c0 848 PRINTS PR01036 Tetracycline resistance protein TetB signature 70 94 6.4E-5 T 29-03-2018 SMALA_RS30920 875a36fe410624e2de198150da7812c0 848 SUPERFAMILY SSF49464 684 772 1.73E-12 T 29-03-2018 IPR008969 Carboxypeptidase-like, regulatory domain SMALA_RS30920 875a36fe410624e2de198150da7812c0 848 SUPERFAMILY SSF103473 53 251 6.28E-70 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS30920 875a36fe410624e2de198150da7812c0 848 SUPERFAMILY SSF103473 301 473 6.28E-70 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS30920 875a36fe410624e2de198150da7812c0 848 SUPERFAMILY SSF103473 526 550 6.28E-70 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS30920 875a36fe410624e2de198150da7812c0 848 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 67 475 3.1E-83 T 29-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 SMALA_RS30920 875a36fe410624e2de198150da7812c0 848 Gene3D G3DSA:2.60.40.1120 600 677 6.9E-8 T 29-03-2018 SMALA_RS30920 875a36fe410624e2de198150da7812c0 848 SUPERFAMILY SSF49464 601 678 4.32E-9 T 29-03-2018 IPR008969 Carboxypeptidase-like, regulatory domain SMALA_RS30920 875a36fe410624e2de198150da7812c0 848 SUPERFAMILY SSF49478 768 836 4.32E-10 T 29-03-2018 SMALA_RS30920 875a36fe410624e2de198150da7812c0 848 Pfam PF13620 Carboxypeptidase regulatory-like domain 768 844 1.7E-11 T 29-03-2018 SMALA_RS30920 875a36fe410624e2de198150da7812c0 848 Pfam PF13620 Carboxypeptidase regulatory-like domain 684 762 5.1E-15 T 29-03-2018 SMALA_RS30920 875a36fe410624e2de198150da7812c0 848 Pfam PF13620 Carboxypeptidase regulatory-like domain 603 678 2.3E-9 T 29-03-2018 SMALA_RS30920 875a36fe410624e2de198150da7812c0 848 Pfam PF07690 Major Facilitator Superfamily 71 464 2.6E-54 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS30920 875a36fe410624e2de198150da7812c0 848 Gene3D G3DSA:2.60.40.1120 678 763 2.2E-13 T 29-03-2018 SMALA_RS30920 875a36fe410624e2de198150da7812c0 848 Gene3D G3DSA:2.60.40.1120 764 846 1.5E-11 T 29-03-2018 SMALA_RS17965 515c0870e59cc9d02dc6455ad1a138fc 111 Pfam PF11774 Lsr2 1 109 8.5E-42 T 29-03-2018 IPR024412 Lsr2 SMALA_RS17965 515c0870e59cc9d02dc6455ad1a138fc 111 ProDom PD026347 LSR2-LIKE LSR2 ANTIGEN IMMUNE PRECURSOR RESPONSE SIGNAL PLASMID LYSYL GP61 1 110 1.0E-37 T 29-03-2018 IPR024412 Lsr2 SMALA_RS24780 89c0d0645eb7e0b69f46898743eba579 744 Pfam PF00912 Transglycosylase 79 255 1.2E-54 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 SMALA_RS24780 89c0d0645eb7e0b69f46898743eba579 744 SUPERFAMILY SSF53955 73 270 1.97E-59 T 29-03-2018 IPR023346 Lysozyme-like domain SMALA_RS24780 89c0d0645eb7e0b69f46898743eba579 744 Gene3D G3DSA:3.40.710.10 279 709 3.8E-88 T 29-03-2018 SMALA_RS24780 89c0d0645eb7e0b69f46898743eba579 744 Gene3D G3DSA:1.10.3810.10 70 273 8.7E-64 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 SMALA_RS24780 89c0d0645eb7e0b69f46898743eba579 744 SUPERFAMILY SSF56601 288 655 2.33E-80 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMALA_RS24780 89c0d0645eb7e0b69f46898743eba579 744 SUPERFAMILY SSF56601 243 259 2.33E-80 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMALA_RS24780 89c0d0645eb7e0b69f46898743eba579 744 Pfam PF00905 Penicillin binding protein transpeptidase domain 353 599 3.0E-34 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 SMALA_RS22725 071ca238dd0756ee3a2d4d4c1ba9de23 698 SUPERFAMILY SSF53756 97 387 4.08E-66 T 29-03-2018 SMALA_RS22725 071ca238dd0756ee3a2d4d4c1ba9de23 698 SUPERFAMILY SSF53756 2 45 4.08E-66 T 29-03-2018 SMALA_RS22725 071ca238dd0756ee3a2d4d4c1ba9de23 698 Gene3D G3DSA:3.40.50.2000 169 372 2.7E-42 T 29-03-2018 SMALA_RS22725 071ca238dd0756ee3a2d4d4c1ba9de23 698 Pfam PF00534 Glycosyl transferases group 1 208 365 6.9E-36 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 SMALA_RS00420 f6159902a1b141e21ac2521f1838e2a5 1116 SUPERFAMILY SSF47336 23 106 9.03E-9 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS00420 f6159902a1b141e21ac2521f1838e2a5 1116 Pfam PF00550 Phosphopantetheine attachment site 25 80 8.4E-7 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS00420 f6159902a1b141e21ac2521f1838e2a5 1116 Gene3D G3DSA:3.30.300.30 991 1095 4.6E-34 T 29-03-2018 SMALA_RS00420 f6159902a1b141e21ac2521f1838e2a5 1116 Gene3D G3DSA:1.10.1200.10 15 124 1.3E-12 T 29-03-2018 SMALA_RS00420 f6159902a1b141e21ac2521f1838e2a5 1116 Pfam PF00668 Condensation domain 141 586 5.0E-69 T 29-03-2018 IPR001242 Condensation domain SMALA_RS00420 f6159902a1b141e21ac2521f1838e2a5 1116 Gene3D G3DSA:2.30.38.10 906 987 9.2E-21 T 29-03-2018 SMALA_RS00420 f6159902a1b141e21ac2521f1838e2a5 1116 Pfam PF13193 AMP-binding enzyme C-terminal domain 1005 1080 1.1E-13 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS00420 f6159902a1b141e21ac2521f1838e2a5 1116 SMART SM00823 Phosphopantetheine attachment site 23 74 0.0059 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS00420 f6159902a1b141e21ac2521f1838e2a5 1116 SUPERFAMILY SSF52777 143 320 1.22E-33 T 29-03-2018 SMALA_RS00420 f6159902a1b141e21ac2521f1838e2a5 1116 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 628 1021 1.2E-127 T 29-03-2018 IPR010071 Amino acid adenylation domain SMALA_RS00420 f6159902a1b141e21ac2521f1838e2a5 1116 Gene3D G3DSA:3.30.559.10 125 333 9.0E-33 T 29-03-2018 SMALA_RS00420 f6159902a1b141e21ac2521f1838e2a5 1116 SUPERFAMILY SSF56801 567 1090 5.76E-147 T 29-03-2018 SMALA_RS00420 f6159902a1b141e21ac2521f1838e2a5 1116 Pfam PF00501 AMP-binding enzyme 607 997 6.4E-89 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS00420 f6159902a1b141e21ac2521f1838e2a5 1116 ProSitePatterns PS00455 Putative AMP-binding domain signature. 747 758 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS00420 f6159902a1b141e21ac2521f1838e2a5 1116 Gene3D G3DSA:3.40.50.980 753 905 1.2E-32 T 29-03-2018 SMALA_RS00420 f6159902a1b141e21ac2521f1838e2a5 1116 Gene3D G3DSA:3.40.50.980 601 752 4.3E-46 T 29-03-2018 SMALA_RS00420 f6159902a1b141e21ac2521f1838e2a5 1116 SUPERFAMILY SSF52777 327 569 8.45E-53 T 29-03-2018 SMALA_RS42365 a1f4b500c001ff990447748b5489671e 273 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 74 85 2.1E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS42365 a1f4b500c001ff990447748b5489671e 273 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 127 135 2.1E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS42365 a1f4b500c001ff990447748b5489671e 273 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 147 166 2.1E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS42365 a1f4b500c001ff990447748b5489671e 273 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2 178 0.0077 T 29-03-2018 SMALA_RS42365 a1f4b500c001ff990447748b5489671e 273 Pfam PF00106 short chain dehydrogenase 5 185 4.2E-50 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS42365 a1f4b500c001ff990447748b5489671e 273 SUPERFAMILY SSF51735 3 245 1.26E-64 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS42365 a1f4b500c001ff990447748b5489671e 273 Gene3D G3DSA:3.40.50.720 2 272 5.4E-64 T 29-03-2018 SMALA_RS42365 a1f4b500c001ff990447748b5489671e 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 137 1.6E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS42365 a1f4b500c001ff990447748b5489671e 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 1.6E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS42365 a1f4b500c001ff990447748b5489671e 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 185 1.6E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS42365 a1f4b500c001ff990447748b5489671e 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 1.6E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS42365 a1f4b500c001ff990447748b5489671e 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 1.6E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS18575 2b956ffe9357472da4beb2abb7d8f564 275 SUPERFAMILY SSF140931 119 252 3.27E-5 T 29-03-2018 IPR003812 Fido domain SMALA_RS18575 2b956ffe9357472da4beb2abb7d8f564 275 Gene3D G3DSA:1.10.3290.10 17 274 1.3E-24 T 29-03-2018 IPR003812 Fido domain SMALA_RS23075 cce9677bb8639db5fef183d3925b3b0a 271 Gene3D G3DSA:3.90.226.10 14 228 2.3E-66 T 29-03-2018 SMALA_RS23075 cce9677bb8639db5fef183d3925b3b0a 271 SUPERFAMILY SSF52096 12 271 2.05E-86 T 29-03-2018 IPR029045 ClpP/crotonase-like domain SMALA_RS23075 cce9677bb8639db5fef183d3925b3b0a 271 Pfam PF00378 Enoyl-CoA hydratase/isomerase 18 270 6.9E-63 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 SMALA_RS23075 cce9677bb8639db5fef183d3925b3b0a 271 Gene3D G3DSA:1.10.12.10 229 271 3.0E-17 T 29-03-2018 IPR014748 Crontonase, C-terminal SMALA_RS34285 aa2b79fe489695c0957a6d0767777278 78 Pfam PF04149 Domain of unknown function (DUF397) 19 70 2.3E-13 T 29-03-2018 IPR007278 Domain of unknown function DUF397 SMALA_RS02510 cf024a1d9328cdbfed2774c919fbe9b0 245 Pfam PF01965 DJ-1/PfpI family 44 216 5.6E-25 T 29-03-2018 IPR002818 DJ-1/PfpI SMALA_RS02510 cf024a1d9328cdbfed2774c919fbe9b0 245 Gene3D G3DSA:3.40.50.880 38 245 1.0E-48 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS02510 cf024a1d9328cdbfed2774c919fbe9b0 245 SUPERFAMILY SSF52317 42 234 3.44E-38 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS30905 1ab539768aaf1c16c9d6b868862b6681 223 SMART SM00567 E-Z type HEAT repeats 54 83 1.7 T 29-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 SMALA_RS30905 1ab539768aaf1c16c9d6b868862b6681 223 SMART SM00567 E-Z type HEAT repeats 154 183 1.0 T 29-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 SMALA_RS30905 1ab539768aaf1c16c9d6b868862b6681 223 SMART SM00567 E-Z type HEAT repeats 85 114 300.0 T 29-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 SMALA_RS30905 1ab539768aaf1c16c9d6b868862b6681 223 Pfam PF03130 PBS lyase HEAT-like repeat 158 182 5.8E-5 T 29-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 SMALA_RS30905 1ab539768aaf1c16c9d6b868862b6681 223 SUPERFAMILY SSF48371 137 193 1.21E-6 T 29-03-2018 IPR016024 Armadillo-type fold GO:0005488 SMALA_RS30905 1ab539768aaf1c16c9d6b868862b6681 223 SUPERFAMILY SSF48371 53 100 1.21E-6 T 29-03-2018 IPR016024 Armadillo-type fold GO:0005488 SMALA_RS30905 1ab539768aaf1c16c9d6b868862b6681 223 Gene3D G3DSA:1.25.40.70 3 100 2.3E-5 T 29-03-2018 SMALA_RS30905 1ab539768aaf1c16c9d6b868862b6681 223 Gene3D G3DSA:1.25.40.70 102 200 3.5E-7 T 29-03-2018 SMALA_RS16250 58a909e1a7ece75e96ee1f28e25253eb 448 SUPERFAMILY SSF48264 11 407 1.96E-56 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS16250 58a909e1a7ece75e96ee1f28e25253eb 448 Gene3D G3DSA:1.10.630.10 17 275 3.4E-22 T 29-03-2018 SMALA_RS16250 58a909e1a7ece75e96ee1f28e25253eb 448 PRINTS PR00359 B-class P450 signature 300 327 1.2E-16 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS16250 58a909e1a7ece75e96ee1f28e25253eb 448 PRINTS PR00359 B-class P450 signature 112 123 1.2E-16 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS16250 58a909e1a7ece75e96ee1f28e25253eb 448 PRINTS PR00359 B-class P450 signature 158 174 1.2E-16 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS16250 58a909e1a7ece75e96ee1f28e25253eb 448 PRINTS PR00359 B-class P450 signature 208 230 1.2E-16 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS16250 58a909e1a7ece75e96ee1f28e25253eb 448 Gene3D G3DSA:1.10.630.10 279 415 2.0E-14 T 29-03-2018 SMALA_RS27635 5d4fefd1d343a9bbe08efc214fb3f311 229 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2 177 3.7E-4 T 29-03-2018 SMALA_RS27635 5d4fefd1d343a9bbe08efc214fb3f311 229 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 131 159 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMALA_RS27635 5d4fefd1d343a9bbe08efc214fb3f311 229 Pfam PF00106 short chain dehydrogenase 5 189 3.1E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS27635 5d4fefd1d343a9bbe08efc214fb3f311 229 SUPERFAMILY SSF51735 3 216 1.02E-48 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS27635 5d4fefd1d343a9bbe08efc214fb3f311 229 Gene3D G3DSA:3.40.50.720 1 229 5.5E-50 T 29-03-2018 SMALA_RS27635 5d4fefd1d343a9bbe08efc214fb3f311 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 3.0E-19 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS27635 5d4fefd1d343a9bbe08efc214fb3f311 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 3.0E-19 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS27635 5d4fefd1d343a9bbe08efc214fb3f311 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 118 134 3.0E-19 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS27635 5d4fefd1d343a9bbe08efc214fb3f311 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 182 3.0E-19 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS27635 5d4fefd1d343a9bbe08efc214fb3f311 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 163 3.0E-19 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS13200 a338704ca0d7a9d7c6e91e27091f5c9d 877 Gene3D G3DSA:3.40.50.620 444 531 4.7E-29 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS13200 a338704ca0d7a9d7c6e91e27091f5c9d 877 Gene3D G3DSA:1.10.730.10 532 752 3.7E-66 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMALA_RS13200 a338704ca0d7a9d7c6e91e27091f5c9d 877 Pfam PF08264 Anticodon-binding domain of tRNA 616 757 1.5E-38 T 29-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 SMALA_RS13200 a338704ca0d7a9d7c6e91e27091f5c9d 877 Gene3D G3DSA:3.90.740.10 209 249 6.9E-13 T 29-03-2018 SMALA_RS13200 a338704ca0d7a9d7c6e91e27091f5c9d 877 Gene3D G3DSA:1.10.287.380 803 873 4.1E-22 T 29-03-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 SMALA_RS13200 a338704ca0d7a9d7c6e91e27091f5c9d 877 Gene3D G3DSA:3.90.740.10 250 443 7.6E-60 T 29-03-2018 SMALA_RS13200 a338704ca0d7a9d7c6e91e27091f5c9d 877 Gene3D G3DSA:3.40.50.620 40 208 9.9E-43 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS13200 a338704ca0d7a9d7c6e91e27091f5c9d 877 TIGRFAM TIGR00422 valS: valine--tRNA ligase 20 854 0.0 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 SMALA_RS13200 a338704ca0d7a9d7c6e91e27091f5c9d 877 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 60 71 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMALA_RS13200 a338704ca0d7a9d7c6e91e27091f5c9d 877 SUPERFAMILY SSF50677 210 348 1.57E-52 T 29-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 SMALA_RS13200 a338704ca0d7a9d7c6e91e27091f5c9d 877 SUPERFAMILY SSF46589 810 874 3.56E-14 T 29-03-2018 IPR010978 tRNA-binding arm GO:0000166 SMALA_RS13200 a338704ca0d7a9d7c6e91e27091f5c9d 877 Hamap MF_02004 Valine--tRNA ligase [valS]. 19 875 15.204 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 SMALA_RS13200 a338704ca0d7a9d7c6e91e27091f5c9d 877 SUPERFAMILY SSF52374 355 584 2.09E-133 T 29-03-2018 SMALA_RS13200 a338704ca0d7a9d7c6e91e27091f5c9d 877 SUPERFAMILY SSF52374 18 207 2.09E-133 T 29-03-2018 SMALA_RS13200 a338704ca0d7a9d7c6e91e27091f5c9d 877 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 32 570 2.8E-188 T 29-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMALA_RS13200 a338704ca0d7a9d7c6e91e27091f5c9d 877 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 810 874 3.8E-17 T 29-03-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 SMALA_RS13200 a338704ca0d7a9d7c6e91e27091f5c9d 877 PRINTS PR00986 Valyl-tRNA synthetase signature 485 503 5.7E-38 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 SMALA_RS13200 a338704ca0d7a9d7c6e91e27091f5c9d 877 PRINTS PR00986 Valyl-tRNA synthetase signature 53 64 5.7E-38 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 SMALA_RS13200 a338704ca0d7a9d7c6e91e27091f5c9d 877 PRINTS PR00986 Valyl-tRNA synthetase signature 454 475 5.7E-38 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 SMALA_RS13200 a338704ca0d7a9d7c6e91e27091f5c9d 877 PRINTS PR00986 Valyl-tRNA synthetase signature 245 262 5.7E-38 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 SMALA_RS13200 a338704ca0d7a9d7c6e91e27091f5c9d 877 PRINTS PR00986 Valyl-tRNA synthetase signature 360 373 5.7E-38 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 SMALA_RS13200 a338704ca0d7a9d7c6e91e27091f5c9d 877 SUPERFAMILY SSF47323 586 823 7.29E-52 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMALA_RS35055 f1fb4f0d196366d45ef223a917d6e768 225 SUPERFAMILY SSF56784 12 210 9.67E-42 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS35055 f1fb4f0d196366d45ef223a917d6e768 225 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 128 192 3.0E-10 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMALA_RS35055 f1fb4f0d196366d45ef223a917d6e768 225 Gene3D G3DSA:3.40.50.1000 12 36 0.015 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS35055 f1fb4f0d196366d45ef223a917d6e768 225 Gene3D G3DSA:1.10.150.240 37 81 1.9E-10 T 29-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 SMALA_RS35055 f1fb4f0d196366d45ef223a917d6e768 225 Gene3D G3DSA:3.40.50.1000 82 224 1.1E-20 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS35055 f1fb4f0d196366d45ef223a917d6e768 225 Pfam PF13419 Haloacid dehalogenase-like hydrolase 14 192 1.0E-21 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS31825 e7c67f689017f4b43f821d210d5774fb 285 Pfam PF00005 ABC transporter 27 189 1.5E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS31825 e7c67f689017f4b43f821d210d5774fb 285 SMART SM00382 35 239 1.3E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS31825 e7c67f689017f4b43f821d210d5774fb 285 Gene3D G3DSA:3.40.50.300 2 283 4.6E-69 T 29-03-2018 SMALA_RS31825 e7c67f689017f4b43f821d210d5774fb 285 SUPERFAMILY SSF52540 4 262 1.33E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS31825 e7c67f689017f4b43f821d210d5774fb 285 ProSitePatterns PS00211 ABC transporters family signature. 162 176 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS26545 ce085dc34fd1417e0a2ac54f7c896640 256 Gene3D G3DSA:3.40.50.720 53 256 1.3E-53 T 29-03-2018 SMALA_RS26545 ce085dc34fd1417e0a2ac54f7c896640 256 Gene3D G3DSA:3.40.50.720 4 52 4.7E-11 T 29-03-2018 SMALA_RS26545 ce085dc34fd1417e0a2ac54f7c896640 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 1.4E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS26545 ce085dc34fd1417e0a2ac54f7c896640 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 1.4E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS26545 ce085dc34fd1417e0a2ac54f7c896640 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 1.4E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS26545 ce085dc34fd1417e0a2ac54f7c896640 256 SUPERFAMILY SSF51735 11 254 1.2E-68 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS26545 ce085dc34fd1417e0a2ac54f7c896640 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 21 252 5.0E-54 T 29-03-2018 SMALA_RS26545 ce085dc34fd1417e0a2ac54f7c896640 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 8.6E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS26545 ce085dc34fd1417e0a2ac54f7c896640 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 8.6E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS26545 ce085dc34fd1417e0a2ac54f7c896640 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 8.6E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS26545 ce085dc34fd1417e0a2ac54f7c896640 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 8.6E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS26545 ce085dc34fd1417e0a2ac54f7c896640 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 8.6E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS26545 ce085dc34fd1417e0a2ac54f7c896640 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 8.6E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS02030 5fea47e13cf266d3c2e9e11406b9c74b 442 PIRSF PIRSF006446 1 441 1.4E-113 T 29-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 SMALA_RS02030 5fea47e13cf266d3c2e9e11406b9c74b 442 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 1 424 6.5E-122 T 29-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 SMALA_RS31095 ca288b25c087fa25b56a1fe2be0cc5fe 422 SUPERFAMILY SSF53901 3 257 1.53E-63 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS31095 ca288b25c087fa25b56a1fe2be0cc5fe 422 SMART SM00825 Beta-ketoacyl synthase 5 419 3.4E-13 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS31095 ca288b25c087fa25b56a1fe2be0cc5fe 422 Gene3D G3DSA:3.40.47.10 1 263 1.5E-67 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS31095 ca288b25c087fa25b56a1fe2be0cc5fe 422 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3 252 2.9E-52 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS31095 ca288b25c087fa25b56a1fe2be0cc5fe 422 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 260 374 4.8E-33 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS31095 ca288b25c087fa25b56a1fe2be0cc5fe 422 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 160 176 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS31095 ca288b25c087fa25b56a1fe2be0cc5fe 422 SUPERFAMILY SSF53901 221 417 2.84E-66 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS31095 ca288b25c087fa25b56a1fe2be0cc5fe 422 Gene3D G3DSA:3.40.47.10 268 421 1.5E-40 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS02450 e0069fe145885ccfdbc00215e0384c48 489 Pfam PF01494 FAD binding domain 4 341 5.3E-86 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 SMALA_RS02450 e0069fe145885ccfdbc00215e0384c48 489 SUPERFAMILY SSF51905 3 170 2.25E-68 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS02450 e0069fe145885ccfdbc00215e0384c48 489 SUPERFAMILY SSF51905 272 388 2.25E-68 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS02450 e0069fe145885ccfdbc00215e0384c48 489 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 149 164 1.2E-38 T 29-03-2018 SMALA_RS02450 e0069fe145885ccfdbc00215e0384c48 489 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 291 307 1.2E-38 T 29-03-2018 SMALA_RS02450 e0069fe145885ccfdbc00215e0384c48 489 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 276 291 1.2E-38 T 29-03-2018 SMALA_RS02450 e0069fe145885ccfdbc00215e0384c48 489 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 1.2E-38 T 29-03-2018 SMALA_RS02450 e0069fe145885ccfdbc00215e0384c48 489 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 326 342 1.2E-38 T 29-03-2018 SMALA_RS02450 e0069fe145885ccfdbc00215e0384c48 489 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 308 326 1.2E-38 T 29-03-2018 SMALA_RS02450 e0069fe145885ccfdbc00215e0384c48 489 Gene3D G3DSA:3.50.50.60 2 387 5.6E-69 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS05810 4b36248a88455bb1a08bb1e8ff150d1a 247 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMALA_RS05810 4b36248a88455bb1a08bb1e8ff150d1a 247 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 181 1.4E-5 T 29-03-2018 SMALA_RS05810 4b36248a88455bb1a08bb1e8ff150d1a 247 SUPERFAMILY SSF51735 6 245 1.28E-69 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS05810 4b36248a88455bb1a08bb1e8ff150d1a 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 4.9E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS05810 4b36248a88455bb1a08bb1e8ff150d1a 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 4.9E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS05810 4b36248a88455bb1a08bb1e8ff150d1a 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 4.9E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS05810 4b36248a88455bb1a08bb1e8ff150d1a 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 4.9E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS05810 4b36248a88455bb1a08bb1e8ff150d1a 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 4.9E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS05810 4b36248a88455bb1a08bb1e8ff150d1a 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 5.9E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS05810 4b36248a88455bb1a08bb1e8ff150d1a 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 5.9E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS05810 4b36248a88455bb1a08bb1e8ff150d1a 247 Gene3D G3DSA:3.40.50.720 2 45 1.5E-8 T 29-03-2018 SMALA_RS05810 4b36248a88455bb1a08bb1e8ff150d1a 247 Gene3D G3DSA:3.40.50.720 46 246 1.4E-56 T 29-03-2018 SMALA_RS05810 4b36248a88455bb1a08bb1e8ff150d1a 247 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 245 1.8E-56 T 29-03-2018 SMALA_RS41250 e9e95a0f480b07be2ad6f0221e51aa3c 241 Pfam PF13353 4Fe-4S single cluster domain 14 121 1.7E-16 T 29-03-2018 SMALA_RS41250 e9e95a0f480b07be2ad6f0221e51aa3c 241 Pfam PF04055 Radical SAM superfamily 23 175 3.9E-26 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 SMALA_RS41250 e9e95a0f480b07be2ad6f0221e51aa3c 241 TIGRFAM TIGR02493 PFLA: pyruvate formate-lyase 1-activating enzyme 4 235 1.1E-90 T 29-03-2018 IPR012838 Pyruvate formate-lyase activating enzyme GO:0043365|GO:0055114 SMALA_RS41250 e9e95a0f480b07be2ad6f0221e51aa3c 241 SUPERFAMILY SSF102114 20 214 7.19E-26 T 29-03-2018 SMALA_RS41250 e9e95a0f480b07be2ad6f0221e51aa3c 241 Gene3D G3DSA:3.20.20.70 10 238 1.9E-31 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS41250 e9e95a0f480b07be2ad6f0221e51aa3c 241 ProSitePatterns PS01087 Radical activating enzymes signature. 16 37 - T 29-03-2018 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 SMALA_RS22460 10dcfc09b83b9dc083f2e3c82c767f4d 1160 Pfam PF00562 RNA polymerase Rpb2, domain 6 630 1046 8.2E-155 T 29-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMALA_RS22460 10dcfc09b83b9dc083f2e3c82c767f4d 1160 ProSitePatterns PS01166 RNA polymerases beta chain signature. 868 880 - T 29-03-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMALA_RS22460 10dcfc09b83b9dc083f2e3c82c767f4d 1160 Gene3D G3DSA:3.90.1800.10 1049 1093 1.6E-11 T 29-03-2018 SMALA_RS22460 10dcfc09b83b9dc083f2e3c82c767f4d 1160 Gene3D G3DSA:2.40.50.100 626 697 3.8E-23 T 29-03-2018 SMALA_RS22460 10dcfc09b83b9dc083f2e3c82c767f4d 1160 Pfam PF04565 RNA polymerase Rpb2, domain 3 424 492 2.0E-29 T 29-03-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMALA_RS22460 10dcfc09b83b9dc083f2e3c82c767f4d 1160 Gene3D G3DSA:3.90.1100.10 329 557 3.6E-82 T 29-03-2018 SMALA_RS22460 10dcfc09b83b9dc083f2e3c82c767f4d 1160 Gene3D G3DSA:3.90.1100.10 559 625 3.0E-14 T 29-03-2018 SMALA_RS22460 10dcfc09b83b9dc083f2e3c82c767f4d 1160 Gene3D G3DSA:3.90.1110.10 166 328 4.7E-70 T 29-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMALA_RS22460 10dcfc09b83b9dc083f2e3c82c767f4d 1160 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 23 1124 12.311 T 29-03-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMALA_RS22460 10dcfc09b83b9dc083f2e3c82c767f4d 1160 Pfam PF10385 RNA polymerase beta subunit external 1 domain 502 568 1.2E-25 T 29-03-2018 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMALA_RS22460 10dcfc09b83b9dc083f2e3c82c767f4d 1160 Pfam PF04560 RNA polymerase Rpb2, domain 7 1048 1122 4.1E-27 T 29-03-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMALA_RS22460 10dcfc09b83b9dc083f2e3c82c767f4d 1160 Gene3D G3DSA:2.40.270.10 698 800 7.8E-10 T 29-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMALA_RS22460 10dcfc09b83b9dc083f2e3c82c767f4d 1160 Gene3D G3DSA:2.40.270.10 826 933 9.1E-50 T 29-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMALA_RS22460 10dcfc09b83b9dc083f2e3c82c767f4d 1160 Gene3D G3DSA:2.40.270.10 934 1024 2.4E-17 T 29-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMALA_RS22460 10dcfc09b83b9dc083f2e3c82c767f4d 1160 SUPERFAMILY SSF64484 22 1132 0.0 T 29-03-2018 SMALA_RS22460 10dcfc09b83b9dc083f2e3c82c767f4d 1160 Pfam PF04563 RNA polymerase beta subunit 66 409 8.5E-21 T 29-03-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMALA_RS22460 10dcfc09b83b9dc083f2e3c82c767f4d 1160 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 236 842 0.0 T 29-03-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMALA_RS22460 10dcfc09b83b9dc083f2e3c82c767f4d 1160 Pfam PF04561 RNA polymerase Rpb2, domain 2 169 365 7.5E-29 T 29-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMALA_RS08190 31da675529395b1b274f9ec0f57f6ecf 334 SUPERFAMILY SSF48576 8 332 1.67E-66 T 29-03-2018 IPR008949 Isoprenoid synthase domain SMALA_RS08190 31da675529395b1b274f9ec0f57f6ecf 334 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 83 97 - T 29-03-2018 IPR033749 Polyprenyl synthetase, conserved site SMALA_RS08190 31da675529395b1b274f9ec0f57f6ecf 334 Gene3D G3DSA:1.10.600.10 1 334 1.7E-78 T 29-03-2018 IPR008949 Isoprenoid synthase domain SMALA_RS08190 31da675529395b1b274f9ec0f57f6ecf 334 Pfam PF00348 Polyprenyl synthetase 39 269 1.7E-50 T 29-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 SMALA_RS08190 31da675529395b1b274f9ec0f57f6ecf 334 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 220 232 - T 29-03-2018 IPR033749 Polyprenyl synthetase, conserved site SMALA_RS24515 3d9e2226fce5347e1a1702587fcc610c 490 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 29 490 7.9E-118 T 29-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 SMALA_RS24515 3d9e2226fce5347e1a1702587fcc610c 490 Pfam PF02447 GntP family permease 29 489 2.2E-129 T 29-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 SMALA_RS24515 3d9e2226fce5347e1a1702587fcc610c 490 PIRSF PIRSF002746 23 490 5.3E-164 T 29-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 SMALA_RS28085 b57aac98732dc0c6959dc6c6f8928737 405 Gene3D G3DSA:3.40.50.300 202 405 7.7E-38 T 29-03-2018 SMALA_RS28085 b57aac98732dc0c6959dc6c6f8928737 405 SMART SM00382 204 354 5.2E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS28085 b57aac98732dc0c6959dc6c6f8928737 405 SMART SM00962 205 404 2.7E-100 T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 SMALA_RS28085 b57aac98732dc0c6959dc6c6f8928737 405 SUPERFAMILY SSF52540 203 404 1.03E-47 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS28085 b57aac98732dc0c6959dc6c6f8928737 405 Pfam PF00448 SRP54-type protein, GTPase domain 206 403 1.4E-72 T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 SMALA_RS28085 b57aac98732dc0c6959dc6c6f8928737 405 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 127 402 1.8E-102 T 29-03-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 SMALA_RS28085 b57aac98732dc0c6959dc6c6f8928737 405 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 377 390 - T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 SMALA_RS28085 b57aac98732dc0c6959dc6c6f8928737 405 SMART SM00963 103 183 7.9E-24 T 29-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 SMALA_RS28085 b57aac98732dc0c6959dc6c6f8928737 405 Pfam PF02881 SRP54-type protein, helical bundle domain 114 179 5.5E-13 T 29-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 SMALA_RS28085 b57aac98732dc0c6959dc6c6f8928737 405 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 126 404 57.851 T 29-03-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 SMALA_RS28085 b57aac98732dc0c6959dc6c6f8928737 405 SUPERFAMILY SSF47364 99 177 1.31E-18 T 29-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 SMALA_RS28085 b57aac98732dc0c6959dc6c6f8928737 405 Gene3D G3DSA:1.20.120.140 100 189 1.3E-19 T 29-03-2018 SMALA_RS22695 7d824571d8aee1c5b5e2df1378f3f352 292 Gene3D G3DSA:3.30.750.24 161 279 1.6E-14 T 29-03-2018 IPR002645 STAS domain SMALA_RS22695 7d824571d8aee1c5b5e2df1378f3f352 292 Pfam PF01740 STAS domain 174 261 1.4E-9 T 29-03-2018 IPR002645 STAS domain SMALA_RS22695 7d824571d8aee1c5b5e2df1378f3f352 292 SUPERFAMILY SSF52091 165 275 1.51E-18 T 29-03-2018 IPR002645 STAS domain SMALA_RS22695 7d824571d8aee1c5b5e2df1378f3f352 292 Pfam PF14361 RsbT co-antagonist protein rsbRD N-terminal domain 13 113 8.4E-16 T 29-03-2018 IPR025751 RsbT co-antagonist protein RsbRD, N-terminal domain SMALA_RS41880 700b79665effa4a82a2de948edfa5f04 259 Gene3D G3DSA:3.40.50.360 1 258 4.5E-63 T 29-03-2018 IPR029039 Flavoprotein-like domain SMALA_RS41880 700b79665effa4a82a2de948edfa5f04 259 SUPERFAMILY SSF52218 1 241 4.81E-70 T 29-03-2018 IPR029039 Flavoprotein-like domain SMALA_RS41880 700b79665effa4a82a2de948edfa5f04 259 Pfam PF02525 Flavodoxin-like fold 1 214 4.2E-57 T 29-03-2018 IPR003680 Flavodoxin-like fold SMALA_RS40950 9c236cd848cd5b57e4e555dc99553c10 246 Gene3D G3DSA:3.40.50.720 1 40 1.6E-8 T 29-03-2018 SMALA_RS40950 9c236cd848cd5b57e4e555dc99553c10 246 Gene3D G3DSA:3.40.50.720 41 246 3.9E-70 T 29-03-2018 SMALA_RS40950 9c236cd848cd5b57e4e555dc99553c10 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 1.6E-47 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40950 9c236cd848cd5b57e4e555dc99553c10 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.6E-47 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40950 9c236cd848cd5b57e4e555dc99553c10 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 1.6E-47 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40950 9c236cd848cd5b57e4e555dc99553c10 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 1.6E-47 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40950 9c236cd848cd5b57e4e555dc99553c10 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 1.6E-47 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40950 9c236cd848cd5b57e4e555dc99553c10 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 1.6E-47 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40950 9c236cd848cd5b57e4e555dc99553c10 246 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 190 5.3E-6 T 29-03-2018 SMALA_RS40950 9c236cd848cd5b57e4e555dc99553c10 246 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 7 245 8.0E-93 T 29-03-2018 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 SMALA_RS40950 9c236cd848cd5b57e4e555dc99553c10 246 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 244 1.9E-69 T 29-03-2018 SMALA_RS40950 9c236cd848cd5b57e4e555dc99553c10 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 2.0E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40950 9c236cd848cd5b57e4e555dc99553c10 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 2.0E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40950 9c236cd848cd5b57e4e555dc99553c10 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 2.0E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40950 9c236cd848cd5b57e4e555dc99553c10 246 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMALA_RS40950 9c236cd848cd5b57e4e555dc99553c10 246 SUPERFAMILY SSF51735 5 245 3.36E-87 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS02880 6746c4c6c92a250c93c7523107f8d295 499 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 103 273 2.7E-38 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain SMALA_RS02880 6746c4c6c92a250c93c7523107f8d295 499 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 104 273 1.3E-39 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain SMALA_RS02880 6746c4c6c92a250c93c7523107f8d295 499 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 381 463 1.7E-16 T 29-03-2018 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain SMALA_RS17195 036450a3b6ce98cc7d034598e45204a8 367 Gene3D G3DSA:1.10.230.10 224 313 1.1E-23 T 29-03-2018 IPR016143 Citrate synthase-like, small alpha subdomain SMALA_RS17195 036450a3b6ce98cc7d034598e45204a8 367 ProSitePatterns PS00480 Citrate synthase signature. 242 254 - T 29-03-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 SMALA_RS17195 036450a3b6ce98cc7d034598e45204a8 367 SUPERFAMILY SSF48256 3 354 9.68E-96 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 SMALA_RS17195 036450a3b6ce98cc7d034598e45204a8 367 Gene3D G3DSA:1.10.580.10 1 67 1.0E-12 T 29-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain SMALA_RS17195 036450a3b6ce98cc7d034598e45204a8 367 PRINTS PR00143 Citrate synthase signature 182 210 3.4E-26 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 SMALA_RS17195 036450a3b6ce98cc7d034598e45204a8 367 PRINTS PR00143 Citrate synthase signature 294 310 3.4E-26 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 SMALA_RS17195 036450a3b6ce98cc7d034598e45204a8 367 PRINTS PR00143 Citrate synthase signature 160 175 3.4E-26 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 SMALA_RS17195 036450a3b6ce98cc7d034598e45204a8 367 PRINTS PR00143 Citrate synthase signature 314 328 3.4E-26 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 SMALA_RS17195 036450a3b6ce98cc7d034598e45204a8 367 PRINTS PR00143 Citrate synthase signature 235 255 3.4E-26 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 SMALA_RS17195 036450a3b6ce98cc7d034598e45204a8 367 Gene3D G3DSA:1.10.580.10 77 223 5.6E-36 T 29-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain SMALA_RS17195 036450a3b6ce98cc7d034598e45204a8 367 Pfam PF00285 Citrate synthase, C-terminal domain 7 343 1.1E-85 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 SMALA_RS02485 7c4bdfa50f59ae73b00333e5dbcc9cc7 317 SUPERFAMILY SSF103481 81 172 2.75E-5 T 29-03-2018 SMALA_RS02485 7c4bdfa50f59ae73b00333e5dbcc9cc7 317 Pfam PF00892 EamA-like transporter family 180 311 5.0E-15 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SMALA_RS02485 7c4bdfa50f59ae73b00333e5dbcc9cc7 317 SUPERFAMILY SSF103481 227 314 1.7E-6 T 29-03-2018 SMALA_RS06655 12e85584ee4a8977d6308d70c108af64 347 SUPERFAMILY SSF46785 190 240 9.35E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS06655 12e85584ee4a8977d6308d70c108af64 347 SMART SM00344 195 296 2.2E-5 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 SMALA_RS06655 12e85584ee4a8977d6308d70c108af64 347 SMART SM00344 16 116 0.003 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 SMALA_RS06655 12e85584ee4a8977d6308d70c108af64 347 Pfam PF13404 AsnC-type helix-turn-helix domain 195 230 1.2E-7 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMALA_RS06655 12e85584ee4a8977d6308d70c108af64 347 Pfam PF13404 AsnC-type helix-turn-helix domain 16 53 4.8E-12 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMALA_RS06655 12e85584ee4a8977d6308d70c108af64 347 SUPERFAMILY SSF46785 12 61 7.87E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS06655 12e85584ee4a8977d6308d70c108af64 347 Gene3D G3DSA:1.10.10.10 184 238 5.7E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS06655 12e85584ee4a8977d6308d70c108af64 347 SUPERFAMILY SSF54909 250 329 2.95E-11 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel SMALA_RS06655 12e85584ee4a8977d6308d70c108af64 347 Pfam PF01037 Lrp/AsnC ligand binding domain 259 326 8.9E-12 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain SMALA_RS06655 12e85584ee4a8977d6308d70c108af64 347 Gene3D G3DSA:3.30.70.920 243 335 4.0E-17 T 29-03-2018 SMALA_RS06655 12e85584ee4a8977d6308d70c108af64 347 Gene3D G3DSA:3.30.70.920 64 153 3.7E-4 T 29-03-2018 SMALA_RS06655 12e85584ee4a8977d6308d70c108af64 347 Gene3D G3DSA:1.10.10.10 14 63 1.2E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS40710 cb4f230ea3ff1cd71d795ce095167060 476 Pfam PF01565 FAD binding domain 45 179 4.0E-28 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 SMALA_RS40710 cb4f230ea3ff1cd71d795ce095167060 476 SUPERFAMILY SSF56176 18 211 2.2E-48 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SMALA_RS40710 cb4f230ea3ff1cd71d795ce095167060 476 Gene3D G3DSA:3.30.465.10 97 234 2.4E-37 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SMALA_RS40710 cb4f230ea3ff1cd71d795ce095167060 476 Gene3D G3DSA:3.30.43.10 19 96 1.8E-14 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 SMALA_RS40710 cb4f230ea3ff1cd71d795ce095167060 476 Pfam PF08031 Berberine and berberine like 422 468 1.4E-6 T 29-03-2018 IPR012951 Berberine/berberine-like GO:0016491|GO:0050660|GO:0055114 SMALA_RS40710 cb4f230ea3ff1cd71d795ce095167060 476 ProSitePatterns PS00862 Oxygen oxidoreductases covalent FAD-binding site. 45 78 - T 29-03-2018 IPR006093 Oxygen oxidoreductase covalent FAD-binding site GO:0016491|GO:0055114 SMALA_RS25535 a3ed754f1e9902156699f5681bf7c758 899 SMART SM00091 44 111 1.1E-7 T 29-03-2018 IPR000014 PAS domain SMALA_RS25535 a3ed754f1e9902156699f5681bf7c758 899 SMART SM00091 167 233 2.7E-6 T 29-03-2018 IPR000014 PAS domain SMALA_RS25535 a3ed754f1e9902156699f5681bf7c758 899 SMART SM00065 353 487 9.6E-9 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS25535 a3ed754f1e9902156699f5681bf7c758 899 Pfam PF01590 GAF domain 312 477 1.4E-6 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS25535 a3ed754f1e9902156699f5681bf7c758 899 SUPERFAMILY SSF55781 296 494 3.44E-15 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS25535 a3ed754f1e9902156699f5681bf7c758 899 Gene3D G3DSA:3.30.565.10 761 893 3.6E-12 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS25535 a3ed754f1e9902156699f5681bf7c758 899 SUPERFAMILY SSF55874 796 882 4.93E-6 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS25535 a3ed754f1e9902156699f5681bf7c758 899 Gene3D G3DSA:3.60.40.10 484 758 1.7E-42 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS25535 a3ed754f1e9902156699f5681bf7c758 899 Gene3D G3DSA:3.30.450.40 284 483 4.9E-38 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS25535 a3ed754f1e9902156699f5681bf7c758 899 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 534 756 7.0E-52 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS25535 a3ed754f1e9902156699f5681bf7c758 899 SUPERFAMILY SSF55785 167 281 4.19E-16 T 29-03-2018 IPR000014 PAS domain SMALA_RS25535 a3ed754f1e9902156699f5681bf7c758 899 SUPERFAMILY SSF81606 521 756 2.56E-7 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS25535 a3ed754f1e9902156699f5681bf7c758 899 Pfam PF08448 PAS fold 174 285 9.8E-23 T 29-03-2018 IPR013656 PAS fold-4 SMALA_RS25535 a3ed754f1e9902156699f5681bf7c758 899 Pfam PF08448 PAS fold 55 160 1.0E-8 T 29-03-2018 IPR013656 PAS fold-4 SMALA_RS25535 a3ed754f1e9902156699f5681bf7c758 899 SMART SM00331 508 755 7.5E-44 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS25535 a3ed754f1e9902156699f5681bf7c758 899 Pfam PF13581 Histidine kinase-like ATPase domain 769 858 1.6E-6 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS25535 a3ed754f1e9902156699f5681bf7c758 899 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 171 289 1.4E-7 T 29-03-2018 IPR000014 PAS domain SMALA_RS25535 a3ed754f1e9902156699f5681bf7c758 899 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 48 163 1.3E-8 T 29-03-2018 IPR000014 PAS domain SMALA_RS25535 a3ed754f1e9902156699f5681bf7c758 899 Gene3D G3DSA:3.30.450.20 47 157 2.7E-17 T 29-03-2018 SMALA_RS25535 a3ed754f1e9902156699f5681bf7c758 899 SUPERFAMILY SSF55785 49 157 1.96E-11 T 29-03-2018 IPR000014 PAS domain SMALA_RS25535 a3ed754f1e9902156699f5681bf7c758 899 Gene3D G3DSA:3.30.450.20 158 283 1.5E-23 T 29-03-2018 SMALA_RS14245 754b878f277de28ce786920c506cb3c8 440 Pfam PF01965 DJ-1/PfpI family 60 191 3.8E-14 T 29-03-2018 IPR002818 DJ-1/PfpI SMALA_RS14245 754b878f277de28ce786920c506cb3c8 440 Gene3D G3DSA:1.10.10.60 248 283 3.6E-7 T 29-03-2018 SMALA_RS14245 754b878f277de28ce786920c506cb3c8 440 Gene3D G3DSA:1.10.10.60 284 344 2.8E-13 T 29-03-2018 SMALA_RS14245 754b878f277de28ce786920c506cb3c8 440 SUPERFAMILY SSF46689 284 334 1.66E-9 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS14245 754b878f277de28ce786920c506cb3c8 440 Pfam PF12833 Helix-turn-helix domain 253 331 6.2E-19 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS14245 754b878f277de28ce786920c506cb3c8 440 SMART SM00342 247 330 1.1E-21 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS14245 754b878f277de28ce786920c506cb3c8 440 Gene3D G3DSA:3.40.50.880 17 247 5.6E-59 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS14245 754b878f277de28ce786920c506cb3c8 440 SUPERFAMILY SSF52317 24 212 1.53E-45 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS14245 754b878f277de28ce786920c506cb3c8 440 SUPERFAMILY SSF46689 232 280 5.12E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS10780 9b15ca8dcb5ae5cce88d4120970e2816 351 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 87 4.6E-5 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS10780 9b15ca8dcb5ae5cce88d4120970e2816 351 Pfam PF13602 Zinc-binding dehydrogenase 187 336 8.1E-20 T 29-03-2018 SMALA_RS10780 9b15ca8dcb5ae5cce88d4120970e2816 351 SUPERFAMILY SSF50129 9 140 1.14E-31 T 29-03-2018 IPR011032 GroES-like SMALA_RS10780 9b15ca8dcb5ae5cce88d4120970e2816 351 SMART SM00829 9 336 1.3E-21 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS10780 9b15ca8dcb5ae5cce88d4120970e2816 351 SUPERFAMILY SSF51735 114 269 4.75E-37 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS10780 9b15ca8dcb5ae5cce88d4120970e2816 351 Gene3D G3DSA:3.40.50.720 135 322 9.1E-35 T 29-03-2018 SMALA_RS10780 9b15ca8dcb5ae5cce88d4120970e2816 351 Gene3D G3DSA:3.90.180.10 1 134 3.3E-34 T 29-03-2018 SMALA_RS25565 da572ebea7aeee23dd0e00f57adb4e76 631 SUPERFAMILY SSF50447 159 182 3.93E-31 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain SMALA_RS25565 da572ebea7aeee23dd0e00f57adb4e76 631 SUPERFAMILY SSF50447 209 313 3.93E-31 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain SMALA_RS25565 da572ebea7aeee23dd0e00f57adb4e76 631 SMART SM00838 421 509 0.0078 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like SMALA_RS25565 da572ebea7aeee23dd0e00f57adb4e76 631 Pfam PF00009 Elongation factor Tu GTP binding domain 6 196 3.9E-52 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMALA_RS25565 da572ebea7aeee23dd0e00f57adb4e76 631 SUPERFAMILY SSF52540 4 219 5.22E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS25565 da572ebea7aeee23dd0e00f57adb4e76 631 SUPERFAMILY SSF54980 317 413 3.6E-10 T 29-03-2018 IPR035647 EF-G domain III/V-like SMALA_RS25565 da572ebea7aeee23dd0e00f57adb4e76 631 Pfam PF03144 Elongation factor Tu domain 2 233 303 1.7E-10 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 SMALA_RS25565 da572ebea7aeee23dd0e00f57adb4e76 631 Gene3D G3DSA:3.40.50.300 2 208 1.6E-36 T 29-03-2018 SMALA_RS25565 da572ebea7aeee23dd0e00f57adb4e76 631 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 7 624 1.0E-287 T 29-03-2018 IPR006298 GTP-binding protein TypA GO:0005525 SMALA_RS25565 da572ebea7aeee23dd0e00f57adb4e76 631 SUPERFAMILY SSF54980 424 538 4.68E-28 T 29-03-2018 IPR035647 EF-G domain III/V-like SMALA_RS25565 da572ebea7aeee23dd0e00f57adb4e76 631 Gene3D G3DSA:3.30.70.870 317 427 9.6E-27 T 29-03-2018 SMALA_RS25565 da572ebea7aeee23dd0e00f57adb4e76 631 Gene3D G3DSA:2.40.50.250 508 598 1.4E-37 T 29-03-2018 SMALA_RS25565 da572ebea7aeee23dd0e00f57adb4e76 631 Gene3D G3DSA:2.40.30.10 209 316 4.3E-23 T 29-03-2018 SMALA_RS25565 da572ebea7aeee23dd0e00f57adb4e76 631 Gene3D G3DSA:3.30.70.240 428 504 4.2E-17 T 29-03-2018 SMALA_RS25565 da572ebea7aeee23dd0e00f57adb4e76 631 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 7 150 1.8E-22 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 SMALA_RS25565 da572ebea7aeee23dd0e00f57adb4e76 631 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 46 61 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site SMALA_RS25565 da572ebea7aeee23dd0e00f57adb4e76 631 PRINTS PR00315 GTP-binding elongation factor signature 53 61 1.4E-15 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMALA_RS25565 da572ebea7aeee23dd0e00f57adb4e76 631 PRINTS PR00315 GTP-binding elongation factor signature 9 22 1.4E-15 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMALA_RS25565 da572ebea7aeee23dd0e00f57adb4e76 631 PRINTS PR00315 GTP-binding elongation factor signature 79 89 1.4E-15 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMALA_RS25565 da572ebea7aeee23dd0e00f57adb4e76 631 PRINTS PR00315 GTP-binding elongation factor signature 131 140 1.4E-15 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMALA_RS25565 da572ebea7aeee23dd0e00f57adb4e76 631 PRINTS PR00315 GTP-binding elongation factor signature 95 106 1.4E-15 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMALA_RS25565 da572ebea7aeee23dd0e00f57adb4e76 631 Pfam PF00679 Elongation factor G C-terminus 422 505 2.8E-21 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like SMALA_RS39700 76f48bec9b3af828a0ea2574bd232b6a 295 Gene3D G3DSA:3.40.50.620 1 148 7.6E-28 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS39700 76f48bec9b3af828a0ea2574bd232b6a 295 SUPERFAMILY SSF52402 162 292 1.67E-19 T 29-03-2018 SMALA_RS39700 76f48bec9b3af828a0ea2574bd232b6a 295 Gene3D G3DSA:3.40.50.620 153 292 2.3E-22 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS39700 76f48bec9b3af828a0ea2574bd232b6a 295 SUPERFAMILY SSF52402 3 138 3.52E-24 T 29-03-2018 SMALA_RS39700 76f48bec9b3af828a0ea2574bd232b6a 295 Pfam PF00582 Universal stress protein family 1 136 2.2E-21 T 29-03-2018 IPR006016 UspA GO:0006950 SMALA_RS39700 76f48bec9b3af828a0ea2574bd232b6a 295 Pfam PF00582 Universal stress protein family 162 292 1.0E-13 T 29-03-2018 IPR006016 UspA GO:0006950 SMALA_RS39700 76f48bec9b3af828a0ea2574bd232b6a 295 PRINTS PR01438 Universal stress protein signature 96 108 7.6E-13 T 29-03-2018 IPR006015 Universal stress protein A SMALA_RS39700 76f48bec9b3af828a0ea2574bd232b6a 295 PRINTS PR01438 Universal stress protein signature 2 20 7.6E-13 T 29-03-2018 IPR006015 Universal stress protein A SMALA_RS39700 76f48bec9b3af828a0ea2574bd232b6a 295 PRINTS PR01438 Universal stress protein signature 114 136 7.6E-13 T 29-03-2018 IPR006015 Universal stress protein A SMALA_RS29780 17ba1b3df13353715ba35344d594bc3e 399 Gene3D G3DSA:3.30.420.40 201 390 7.2E-56 T 29-03-2018 SMALA_RS29780 17ba1b3df13353715ba35344d594bc3e 399 SUPERFAMILY SSF46785 12 71 2.03E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS29780 17ba1b3df13353715ba35344d594bc3e 399 Pfam PF12802 MarR family 17 68 2.2E-8 T 29-03-2018 SMALA_RS29780 17ba1b3df13353715ba35344d594bc3e 399 Gene3D G3DSA:1.10.10.10 8 71 7.8E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS29780 17ba1b3df13353715ba35344d594bc3e 399 ProSitePatterns PS01125 ROK family signature. 215 242 - T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 SMALA_RS29780 17ba1b3df13353715ba35344d594bc3e 399 Gene3D G3DSA:3.30.420.40 72 200 8.1E-32 T 29-03-2018 SMALA_RS29780 17ba1b3df13353715ba35344d594bc3e 399 Pfam PF00480 ROK family 82 378 4.7E-59 T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 SMALA_RS29780 17ba1b3df13353715ba35344d594bc3e 399 SUPERFAMILY SSF53067 79 383 2.26E-56 T 29-03-2018 SMALA_RS41245 ecd68b185ebeefb1f03b2118d5a7d246 753 Gene3D G3DSA:3.20.70.20 6 753 8.4E-289 T 29-03-2018 SMALA_RS41245 ecd68b185ebeefb1f03b2118d5a7d246 753 PIRSF PIRSF000379 12 753 0.0 T 29-03-2018 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 SMALA_RS41245 ecd68b185ebeefb1f03b2118d5a7d246 753 Pfam PF01228 Glycine radical 628 734 7.2E-39 T 29-03-2018 IPR001150 Glycine radical domain GO:0003824|GO:0008152 SMALA_RS41245 ecd68b185ebeefb1f03b2118d5a7d246 753 ProSitePatterns PS00850 Glycine radical domain signature. 723 731 - T 29-03-2018 IPR019777 Formate C-acetyltransferase glycine radical, conserved site SMALA_RS41245 ecd68b185ebeefb1f03b2118d5a7d246 753 TIGRFAM TIGR01255 pyr_form_ly_1: formate acetyltransferase 15 752 0.0 T 29-03-2018 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 SMALA_RS41245 ecd68b185ebeefb1f03b2118d5a7d246 753 SUPERFAMILY SSF51998 11 751 2.66E-271 T 29-03-2018 SMALA_RS41245 ecd68b185ebeefb1f03b2118d5a7d246 753 Pfam PF02901 Pyruvate formate lyase-like 27 612 4.6E-195 T 29-03-2018 IPR004184 Pyruvate formate lyase domain GO:0003824 SMALA_RS00790 5e1f7e8add4a69656c627611b4a389e8 370 SUPERFAMILY SSF53756 76 363 6.04E-20 T 29-03-2018 SMALA_RS00790 5e1f7e8add4a69656c627611b4a389e8 370 Pfam PF06925 Monogalactosyldiacylglycerol (MGDG) synthase 22 167 3.0E-22 T 29-03-2018 IPR009695 Diacylglycerol glucosyltransferase, N-terminal GO:0009247|GO:0016758 SMALA_RS00790 5e1f7e8add4a69656c627611b4a389e8 370 Gene3D G3DSA:3.40.50.2000 200 351 1.7E-15 T 29-03-2018 SMALA_RS00790 5e1f7e8add4a69656c627611b4a389e8 370 Gene3D G3DSA:3.40.50.2000 2 199 2.1E-7 T 29-03-2018 SMALA_RS36430 ead2664e62024c716a02cdb2dd54c1c5 202 Pfam PF06684 Amino acid synthesis 6 182 2.7E-62 T 29-03-2018 IPR009569 Amino acid synthesis, putative SMALA_RS36430 ead2664e62024c716a02cdb2dd54c1c5 202 Gene3D G3DSA:3.30.1330.110 4 193 4.4E-68 T 29-03-2018 IPR009569 Amino acid synthesis, putative SMALA_RS36430 ead2664e62024c716a02cdb2dd54c1c5 202 SUPERFAMILY SSF160519 4 189 1.83E-60 T 29-03-2018 IPR009569 Amino acid synthesis, putative SMALA_RS28665 1d323480c93e7c16fcd246e8aeb6a531 183 Pfam PF10756 Bacterial PH domain 90 145 2.1E-5 T 29-03-2018 IPR019692 Protein of unknown function DUF2581 SMALA_RS33825 20fedf58df35cc2bc2da90754363623e 679 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 549 557 6.3E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS33825 20fedf58df35cc2bc2da90754363623e 679 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 569 588 6.3E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS33825 20fedf58df35cc2bc2da90754363623e 679 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 495 506 6.3E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS33825 20fedf58df35cc2bc2da90754363623e 679 TIGRFAM TIGR02632 RhaD_aldol-ADH: rhamnulose-1-phosphate aldolase/alcohol dehydrogenase 10 679 0.0 T 29-03-2018 IPR013454 Bifunctional rhamnulose-1-phosphate aldolase/alcohol dehydrogenase SMALA_RS33825 20fedf58df35cc2bc2da90754363623e 679 SMART SM01007 11 213 7.1E-32 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal SMALA_RS33825 20fedf58df35cc2bc2da90754363623e 679 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 13 210 1.4E-20 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal SMALA_RS33825 20fedf58df35cc2bc2da90754363623e 679 Gene3D G3DSA:3.40.50.720 406 678 8.1E-55 T 29-03-2018 SMALA_RS33825 20fedf58df35cc2bc2da90754363623e 679 SUPERFAMILY SSF53639 17 218 2.94E-29 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal SMALA_RS33825 20fedf58df35cc2bc2da90754363623e 679 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 427 673 7.0E-47 T 29-03-2018 SMALA_RS33825 20fedf58df35cc2bc2da90754363623e 679 Gene3D G3DSA:3.40.225.10 4 243 3.7E-39 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal SMALA_RS33825 20fedf58df35cc2bc2da90754363623e 679 SUPERFAMILY SSF51735 409 676 2.23E-62 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS33825 20fedf58df35cc2bc2da90754363623e 679 Gene3D G3DSA:3.40.225.10 301 405 0.26 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal SMALA_RS33825 20fedf58df35cc2bc2da90754363623e 679 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 543 559 3.2E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS33825 20fedf58df35cc2bc2da90754363623e 679 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 422 439 3.2E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS33825 20fedf58df35cc2bc2da90754363623e 679 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 495 506 3.2E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS33825 20fedf58df35cc2bc2da90754363623e 679 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 590 607 3.2E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS33825 20fedf58df35cc2bc2da90754363623e 679 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 569 588 3.2E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS05670 192e100800027d717f8301a8a8c746cb 427 SUPERFAMILY SSF51905 270 405 3.56E-6 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS05670 192e100800027d717f8301a8a8c746cb 427 SUPERFAMILY SSF51905 168 222 3.56E-6 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS05670 192e100800027d717f8301a8a8c746cb 427 SUPERFAMILY SSF51905 3 221 1.21E-34 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS05670 192e100800027d717f8301a8a8c746cb 427 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 8 195 1.1E-24 T 29-03-2018 SMALA_RS05670 192e100800027d717f8301a8a8c746cb 427 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 167 185 2.2E-5 T 29-03-2018 SMALA_RS05670 192e100800027d717f8301a8a8c746cb 427 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 2.2E-5 T 29-03-2018 SMALA_RS05670 192e100800027d717f8301a8a8c746cb 427 Gene3D G3DSA:3.50.50.60 2 164 1.8E-31 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS05670 192e100800027d717f8301a8a8c746cb 427 Gene3D G3DSA:3.50.50.60 167 413 5.3E-14 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS05670 192e100800027d717f8301a8a8c746cb 427 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 127 136 4.1E-9 T 29-03-2018 SMALA_RS05670 192e100800027d717f8301a8a8c746cb 427 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 167 192 4.1E-9 T 29-03-2018 SMALA_RS05670 192e100800027d717f8301a8a8c746cb 427 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 4.1E-9 T 29-03-2018 SMALA_RS36690 e4fb22bcc974306182eb5a489a76f547 270 SUPERFAMILY SSF53335 11 241 2.41E-53 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS36690 e4fb22bcc974306182eb5a489a76f547 270 Gene3D G3DSA:3.40.50.150 30 269 3.9E-42 T 29-03-2018 SMALA_RS36690 e4fb22bcc974306182eb5a489a76f547 270 Pfam PF08241 Methyltransferase domain 70 167 1.0E-20 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 SMALA_RS10060 dc425966b7e4a93f45b708f3da338e62 214 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 7 213 30.31 T 29-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 SMALA_RS10060 dc425966b7e4a93f45b708f3da338e62 214 SUPERFAMILY SSF52317 6 212 4.89E-53 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS10060 dc425966b7e4a93f45b708f3da338e62 214 Gene3D G3DSA:3.40.50.880 2 214 1.9E-44 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS10060 dc425966b7e4a93f45b708f3da338e62 214 Pfam PF00117 Glutamine amidotransferase class-I 10 210 1.1E-17 T 29-03-2018 IPR017926 Glutamine amidotransferase SMALA_RS10060 dc425966b7e4a93f45b708f3da338e62 214 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 8 212 4.9E-60 T 29-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 SMALA_RS10060 dc425966b7e4a93f45b708f3da338e62 214 PIRSF PIRSF000495 6 214 2.2E-64 T 29-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 SMALA_RS04405 ad99299db84d46101d5863fbba0a013e 354 Gene3D G3DSA:3.40.50.1970 17 178 1.1E-37 T 29-03-2018 SMALA_RS04405 ad99299db84d46101d5863fbba0a013e 354 Gene3D G3DSA:1.20.1090.10 179 351 6.3E-42 T 29-03-2018 SMALA_RS04405 ad99299db84d46101d5863fbba0a013e 354 SUPERFAMILY SSF56796 19 341 6.02E-89 T 29-03-2018 SMALA_RS04405 ad99299db84d46101d5863fbba0a013e 354 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 17 347 30.441 T 29-03-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 SMALA_RS04405 ad99299db84d46101d5863fbba0a013e 354 Pfam PF01761 3-dehydroquinate synthase 74 316 2.4E-79 T 29-03-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 SMALA_RS26155 b78fc67f50969ed1dabe31bd22d6d529 107 SUPERFAMILY SSF103481 6 105 5.23E-18 T 29-03-2018 SMALA_RS26155 b78fc67f50969ed1dabe31bd22d6d529 107 Pfam PF00893 Small Multidrug Resistance protein 1 93 2.0E-25 T 29-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 SMALA_RS20000 3fd611dd723d84d69d6f8e575ed5e16c 325 Gene3D G3DSA:3.90.180.10 1 133 3.5E-39 T 29-03-2018 SMALA_RS20000 3fd611dd723d84d69d6f8e575ed5e16c 325 TIGRFAM TIGR02824 quinone_pig3: putative NAD(P)H quinone oxidoreductase, PIG3 family 1 325 1.0E-139 T 29-03-2018 IPR014189 Quinone oxidoreductase PIG3 Reactome: R-HSA-6803205 SMALA_RS20000 3fd611dd723d84d69d6f8e575ed5e16c 325 Pfam PF00107 Zinc-binding dehydrogenase 151 266 2.8E-28 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMALA_RS20000 3fd611dd723d84d69d6f8e575ed5e16c 325 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 87 1.0E-9 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS20000 3fd611dd723d84d69d6f8e575ed5e16c 325 Gene3D G3DSA:3.40.50.720 134 252 7.3E-30 T 29-03-2018 SMALA_RS20000 3fd611dd723d84d69d6f8e575ed5e16c 325 SUPERFAMILY SSF50129 1 140 1.29E-39 T 29-03-2018 IPR011032 GroES-like SMALA_RS20000 3fd611dd723d84d69d6f8e575ed5e16c 325 SMART SM00829 10 323 7.9E-57 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS20000 3fd611dd723d84d69d6f8e575ed5e16c 325 Gene3D G3DSA:3.90.180.10 253 325 3.8E-7 T 29-03-2018 SMALA_RS20000 3fd611dd723d84d69d6f8e575ed5e16c 325 SUPERFAMILY SSF51735 111 286 9.24E-47 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS17305 8fde37bf417a3dbbaadffdc50e02ee7b 194 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 1 190 9.3E-32 T 29-03-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 SMALA_RS17305 8fde37bf417a3dbbaadffdc50e02ee7b 194 SUPERFAMILY SSF55144 1 193 3.66E-37 T 29-03-2018 IPR009097 Cyclic phosphodiesterase SMALA_RS17305 8fde37bf417a3dbbaadffdc50e02ee7b 194 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 1 192 22.153 T 29-03-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 SMALA_RS17305 8fde37bf417a3dbbaadffdc50e02ee7b 194 Gene3D G3DSA:3.90.1140.10 1 194 9.3E-42 T 29-03-2018 SMALA_RS17305 8fde37bf417a3dbbaadffdc50e02ee7b 194 Pfam PF13563 2'-5' RNA ligase superfamily 16 171 1.1E-17 T 29-03-2018 SMALA_RS07515 2864f0aa0182a2ae48dd0188d73d229b 619 SUPERFAMILY SSF52540 228 583 2.98E-36 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS07515 2864f0aa0182a2ae48dd0188d73d229b 619 Gene3D G3DSA:3.40.50.300 236 592 3.9E-21 T 29-03-2018 SMALA_RS07515 2864f0aa0182a2ae48dd0188d73d229b 619 Pfam PF12846 AAA-like domain 440 516 1.5E-7 T 29-03-2018 SMALA_RS27805 4ecea9b7d65b374932e291c521e01359 361 PIRSF PIRSF006468 5 361 2.4E-129 T 29-03-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 SMALA_RS27805 4ecea9b7d65b374932e291c521e01359 361 TIGRFAM TIGR01123 ilvE_II: branched-chain amino acid aminotransferase 48 358 2.5E-130 T 29-03-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 SMALA_RS27805 4ecea9b7d65b374932e291c521e01359 361 ProSitePatterns PS00770 Aminotransferases class-IV signature. 237 266 - T 29-03-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 SMALA_RS27805 4ecea9b7d65b374932e291c521e01359 361 SUPERFAMILY SSF56752 12 358 5.62E-118 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 SMALA_RS27805 4ecea9b7d65b374932e291c521e01359 361 Pfam PF01063 Amino-transferase class IV 74 317 5.3E-33 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 SMALA_RS27805 4ecea9b7d65b374932e291c521e01359 361 Gene3D G3DSA:3.20.10.10 181 356 2.7E-53 T 29-03-2018 SMALA_RS27805 4ecea9b7d65b374932e291c521e01359 361 Gene3D G3DSA:3.30.470.10 2 180 2.0E-68 T 29-03-2018 SMALA_RS35615 2a6dddccf8a7718df15dffe30e0bf099 535 SUPERFAMILY SSF56601 42 358 6.13E-79 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMALA_RS35615 2a6dddccf8a7718df15dffe30e0bf099 535 Gene3D G3DSA:3.40.710.10 36 368 7.3E-79 T 29-03-2018 SMALA_RS35615 2a6dddccf8a7718df15dffe30e0bf099 535 Pfam PF00144 Beta-lactamase 44 352 1.1E-66 T 29-03-2018 IPR001466 Beta-lactamase-related SMALA_RS21350 55b7591b386f58a14fbb40bbb17e56c3 356 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 153 353 1.9E-26 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS21350 55b7591b386f58a14fbb40bbb17e56c3 356 Gene3D G3DSA:1.10.3720.10 82 356 1.6E-41 T 29-03-2018 SMALA_RS21350 55b7591b386f58a14fbb40bbb17e56c3 356 SUPERFAMILY SSF161098 89 343 1.7E-42 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS21350 55b7591b386f58a14fbb40bbb17e56c3 356 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 82 348 2.5E-85 T 29-03-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 SMALA_RS03980 8a4376b6397e032b0cad729e38271baa 453 SUPERFAMILY SSF53187 361 445 1.23E-54 T 29-03-2018 SMALA_RS03980 8a4376b6397e032b0cad729e38271baa 453 SUPERFAMILY SSF53187 7 199 1.23E-54 T 29-03-2018 SMALA_RS03980 8a4376b6397e032b0cad729e38271baa 453 Pfam PF07687 Peptidase dimerisation domain 205 347 1.9E-13 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain SMALA_RS03980 8a4376b6397e032b0cad729e38271baa 453 Pfam PF01546 Peptidase family M20/M25/M40 86 437 4.1E-37 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 SMALA_RS03980 8a4376b6397e032b0cad729e38271baa 453 Gene3D G3DSA:3.40.630.10 6 202 2.1E-39 T 29-03-2018 SMALA_RS03980 8a4376b6397e032b0cad729e38271baa 453 Gene3D G3DSA:3.30.70.360 203 357 1.4E-36 T 29-03-2018 SMALA_RS26345 c781e56b97ca34b5c76cecd9bd9b5554 344 Gene3D G3DSA:1.10.10.10 193 246 2.0E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS26345 c781e56b97ca34b5c76cecd9bd9b5554 344 Gene3D G3DSA:1.10.601.10 67 192 6.1E-28 T 29-03-2018 SMALA_RS26345 c781e56b97ca34b5c76cecd9bd9b5554 344 PRINTS PR00046 Major sigma-70 factor signature 325 336 1.1E-9 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS26345 c781e56b97ca34b5c76cecd9bd9b5554 344 PRINTS PR00046 Major sigma-70 factor signature 310 325 1.1E-9 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS26345 c781e56b97ca34b5c76cecd9bd9b5554 344 PRINTS PR00046 Major sigma-70 factor signature 148 161 1.1E-9 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS26345 c781e56b97ca34b5c76cecd9bd9b5554 344 PRINTS PR00046 Major sigma-70 factor signature 172 180 1.1E-9 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS26345 c781e56b97ca34b5c76cecd9bd9b5554 344 PRINTS PR00046 Major sigma-70 factor signature 293 305 1.1E-9 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS26345 c781e56b97ca34b5c76cecd9bd9b5554 344 Pfam PF04542 Sigma-70 region 2 124 193 4.5E-21 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS26345 c781e56b97ca34b5c76cecd9bd9b5554 344 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 120 340 1.7E-37 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS26345 c781e56b97ca34b5c76cecd9bd9b5554 344 Gene3D G3DSA:1.10.10.10 261 344 5.9E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS26345 c781e56b97ca34b5c76cecd9bd9b5554 344 Pfam PF04539 Sigma-70 region 3 207 263 2.4E-15 T 29-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS26345 c781e56b97ca34b5c76cecd9bd9b5554 344 SUPERFAMILY SSF88659 260 340 1.61E-16 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS26345 c781e56b97ca34b5c76cecd9bd9b5554 344 Pfam PF04545 Sigma-70, region 4 289 338 3.0E-16 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS26345 c781e56b97ca34b5c76cecd9bd9b5554 344 SUPERFAMILY SSF88659 197 271 6.98E-16 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS26345 c781e56b97ca34b5c76cecd9bd9b5554 344 SUPERFAMILY SSF88946 84 193 2.75E-32 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS26345 c781e56b97ca34b5c76cecd9bd9b5554 344 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 118 340 7.8E-96 T 29-03-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS15780 1c29855dca47a7a5d5323669497b5d44 385 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 29 362 8.9E-104 T 29-03-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 SMALA_RS15780 1c29855dca47a7a5d5323669497b5d44 385 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 48 363 1.7E-82 T 29-03-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 SMALA_RS15780 1c29855dca47a7a5d5323669497b5d44 385 SUPERFAMILY SSF100950 27 363 2.23E-93 T 29-03-2018 SMALA_RS15780 1c29855dca47a7a5d5323669497b5d44 385 Hamap MF_01678 Putative methylthioribose-1-phosphate isomerase [mtnA]. 16 373 34.992 T 29-03-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 SMALA_RS15780 1c29855dca47a7a5d5323669497b5d44 385 Gene3D G3DSA:3.40.50.10470 156 378 8.4E-59 T 29-03-2018 SMALA_RS15780 1c29855dca47a7a5d5323669497b5d44 385 Gene3D G3DSA:1.20.120.420 18 155 2.0E-33 T 29-03-2018 IPR027363 Methylthioribose-1-phosphate isomerase-like, N-terminal domain KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 SMALA_RS15780 1c29855dca47a7a5d5323669497b5d44 385 Pfam PF01008 Initiation factor 2 subunit family 86 363 1.9E-59 T 29-03-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 SMALA_RS40265 71c412ca6e6d313c397259857d0d7e64 298 SUPERFAMILY SSF54427 175 259 3.43E-10 T 29-03-2018 IPR032710 NTF2-like domain SMALA_RS40265 71c412ca6e6d313c397259857d0d7e64 298 Gene3D G3DSA:3.10.450.50 158 288 1.0E-13 T 29-03-2018 SMALA_RS40265 71c412ca6e6d313c397259857d0d7e64 298 SUPERFAMILY SSF88659 111 166 7.1E-10 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS40265 71c412ca6e6d313c397259857d0d7e64 298 TIGRFAM TIGR02957 SigX4: RNA polymerase sigma-70 factor, TIGR02957 family 16 290 9.4E-102 T 29-03-2018 IPR014303 RNA polymerase sigma-70, ECF type SMALA_RS40265 71c412ca6e6d313c397259857d0d7e64 298 Gene3D G3DSA:1.10.10.10 81 157 5.1E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS40265 71c412ca6e6d313c397259857d0d7e64 298 Pfam PF08281 Sigma-70, region 4 114 165 2.0E-12 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS40265 71c412ca6e6d313c397259857d0d7e64 298 Gene3D G3DSA:1.10.1740.10 3 80 1.6E-12 T 29-03-2018 SMALA_RS40265 71c412ca6e6d313c397259857d0d7e64 298 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 17 166 1.1E-14 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS40265 71c412ca6e6d313c397259857d0d7e64 298 SUPERFAMILY SSF88946 15 75 7.06E-12 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS40265 71c412ca6e6d313c397259857d0d7e64 298 Pfam PF04542 Sigma-70 region 2 21 83 1.7E-14 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS31545 39d951ebbdb7a6ffa5e245eb36d3b9e4 501 Gene3D G3DSA:3.40.605.10 11 278 6.6E-94 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS31545 39d951ebbdb7a6ffa5e245eb36d3b9e4 501 Gene3D G3DSA:3.40.309.10 279 470 8.1E-68 T 29-03-2018 SMALA_RS31545 39d951ebbdb7a6ffa5e245eb36d3b9e4 501 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 260 267 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 SMALA_RS31545 39d951ebbdb7a6ffa5e245eb36d3b9e4 501 Pfam PF00171 Aldehyde dehydrogenase family 24 483 1.4E-161 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS31545 39d951ebbdb7a6ffa5e245eb36d3b9e4 501 SUPERFAMILY SSF53720 14 487 1.27E-163 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMALA_RS09750 a30b7c006de2ec57abd4f6ad088e116b 942 SUPERFAMILY SSF52540 27 175 8.78E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS09750 a30b7c006de2ec57abd4f6ad088e116b 942 SUPERFAMILY SSF52540 247 404 8.78E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS09750 a30b7c006de2ec57abd4f6ad088e116b 942 SMART SM00847 454 547 6.2E-14 T 29-03-2018 IPR007502 Helicase-associated domain GO:0004386 SMALA_RS09750 a30b7c006de2ec57abd4f6ad088e116b 942 Gene3D G3DSA:3.40.50.300 14 175 9.7E-24 T 29-03-2018 SMALA_RS09750 a30b7c006de2ec57abd4f6ad088e116b 942 Pfam PF04408 Helicase associated domain (HA2) 455 513 1.1E-10 T 29-03-2018 IPR007502 Helicase-associated domain GO:0004386 SMALA_RS09750 a30b7c006de2ec57abd4f6ad088e116b 942 Pfam PF00271 Helicase conserved C-terminal domain 272 392 2.2E-12 T 29-03-2018 IPR001650 Helicase, C-terminal SMALA_RS09750 a30b7c006de2ec57abd4f6ad088e116b 942 Gene3D G3DSA:3.40.50.300 238 412 6.0E-37 T 29-03-2018 SMALA_RS09750 a30b7c006de2ec57abd4f6ad088e116b 942 SMART SM00487 13 197 2.4E-15 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain SMALA_RS09750 a30b7c006de2ec57abd4f6ad088e116b 942 SMART SM00490 294 394 1.6E-11 T 29-03-2018 IPR001650 Helicase, C-terminal SMALA_RS09750 a30b7c006de2ec57abd4f6ad088e116b 942 Pfam PF08482 ATP-dependent helicase C-terminal 794 926 8.6E-48 T 29-03-2018 IPR013689 ATP-dependent RNA helicase HrpB, C-terminal SMALA_RS09750 a30b7c006de2ec57abd4f6ad088e116b 942 Pfam PF00270 DEAD/DEAH box helicase 19 173 9.1E-6 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 SMALA_RS00940 f3dac65a4b97ac2e70192e3fa2ed1864 406 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 208 213 - T 29-03-2018 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 SMALA_RS00940 f3dac65a4b97ac2e70192e3fa2ed1864 406 PIRSF PIRSF001134 1 371 1.6E-126 T 29-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMALA_RS00940 f3dac65a4b97ac2e70192e3fa2ed1864 406 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 268 288 3.0E-42 T 29-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMALA_RS00940 f3dac65a4b97ac2e70192e3fa2ed1864 406 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 333 347 3.0E-42 T 29-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMALA_RS00940 f3dac65a4b97ac2e70192e3fa2ed1864 406 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 206 220 3.0E-42 T 29-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMALA_RS00940 f3dac65a4b97ac2e70192e3fa2ed1864 406 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 289 306 3.0E-42 T 29-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMALA_RS00940 f3dac65a4b97ac2e70192e3fa2ed1864 406 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 308 331 3.0E-42 T 29-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMALA_RS00940 f3dac65a4b97ac2e70192e3fa2ed1864 406 Gene3D G3DSA:2.40.10.10 179 265 8.5E-23 T 29-03-2018 SMALA_RS00940 f3dac65a4b97ac2e70192e3fa2ed1864 406 Gene3D G3DSA:2.40.10.10 266 355 2.7E-24 T 29-03-2018 SMALA_RS00940 f3dac65a4b97ac2e70192e3fa2ed1864 406 Pfam PF02983 Alpha-lytic protease prodomain 106 161 8.2E-15 T 29-03-2018 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 SMALA_RS00940 f3dac65a4b97ac2e70192e3fa2ed1864 406 Pfam PF00089 Trypsin 207 361 1.5E-11 T 29-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 SMALA_RS00940 f3dac65a4b97ac2e70192e3fa2ed1864 406 Gene3D G3DSA:3.30.300.50 41 102 1.7E-16 T 29-03-2018 IPR035070 Streptogrisin prodomain SMALA_RS00940 f3dac65a4b97ac2e70192e3fa2ed1864 406 SUPERFAMILY SSF50494 185 364 1.8E-38 T 29-03-2018 IPR009003 Peptidase S1, PA clan SMALA_RS00940 f3dac65a4b97ac2e70192e3fa2ed1864 406 Gene3D G3DSA:3.30.300.50 103 173 1.2E-17 T 29-03-2018 IPR035070 Streptogrisin prodomain SMALA_RS00940 f3dac65a4b97ac2e70192e3fa2ed1864 406 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 317 328 - T 29-03-2018 IPR033116 Serine proteases, trypsin family, serine active site SMALA_RS35775 02b67602a92939af3fb0fe8165b0a91f 98 Pfam PF04149 Domain of unknown function (DUF397) 24 71 8.1E-12 T 29-03-2018 IPR007278 Domain of unknown function DUF397 SMALA_RS31230 486c2a0b413ae95cc4e0570954e8bcc9 391 Gene3D G3DSA:2.40.10.10 203 285 6.9E-20 T 29-03-2018 SMALA_RS31230 486c2a0b413ae95cc4e0570954e8bcc9 391 Pfam PF00089 Trypsin 231 381 1.0E-11 T 29-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 SMALA_RS31230 486c2a0b413ae95cc4e0570954e8bcc9 391 SUPERFAMILY SSF50494 207 385 1.47E-35 T 29-03-2018 IPR009003 Peptidase S1, PA clan SMALA_RS31230 486c2a0b413ae95cc4e0570954e8bcc9 391 Gene3D G3DSA:2.40.10.10 286 376 4.7E-20 T 29-03-2018 SMALA_RS31230 486c2a0b413ae95cc4e0570954e8bcc9 391 Pfam PF02983 Alpha-lytic protease prodomain 126 185 2.6E-14 T 29-03-2018 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 SMALA_RS31230 486c2a0b413ae95cc4e0570954e8bcc9 391 PIRSF PIRSF001134 2 391 6.3E-137 T 29-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMALA_RS31230 486c2a0b413ae95cc4e0570954e8bcc9 391 SUPERFAMILY SSF54806 127 193 3.66E-6 T 29-03-2018 IPR035071 Alpha-lytic protease prodomain SMALA_RS31230 486c2a0b413ae95cc4e0570954e8bcc9 391 Gene3D G3DSA:3.30.300.50 123 194 8.0E-12 T 29-03-2018 IPR035070 Streptogrisin prodomain SMALA_RS31230 486c2a0b413ae95cc4e0570954e8bcc9 391 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 354 368 4.9E-41 T 29-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMALA_RS31230 486c2a0b413ae95cc4e0570954e8bcc9 391 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 311 328 4.9E-41 T 29-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMALA_RS31230 486c2a0b413ae95cc4e0570954e8bcc9 391 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 330 353 4.9E-41 T 29-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMALA_RS31230 486c2a0b413ae95cc4e0570954e8bcc9 391 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 230 244 4.9E-41 T 29-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMALA_RS31230 486c2a0b413ae95cc4e0570954e8bcc9 391 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 290 310 4.9E-41 T 29-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMALA_RS31230 486c2a0b413ae95cc4e0570954e8bcc9 391 Gene3D G3DSA:3.30.300.50 45 122 2.0E-20 T 29-03-2018 IPR035070 Streptogrisin prodomain SMALA_RS24445 42f31a99810d6549a2fc96a9323e9e72 403 SUPERFAMILY SSF53383 7 398 2.18E-95 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS24445 42f31a99810d6549a2fc96a9323e9e72 403 Gene3D G3DSA:3.90.1150.10 279 403 1.4E-23 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS24445 42f31a99810d6549a2fc96a9323e9e72 403 Gene3D G3DSA:3.40.640.10 52 278 9.9E-51 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS24445 42f31a99810d6549a2fc96a9323e9e72 403 Pfam PF00155 Aminotransferase class I and II 34 391 1.0E-51 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMALA_RS05905 810c63c10a81ed11509f7fb3d8e0925d 443 Gene3D G3DSA:2.30.40.10 5 88 6.2E-20 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS05905 810c63c10a81ed11509f7fb3d8e0925d 443 SUPERFAMILY SSF51338 19 72 4.71E-23 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS05905 810c63c10a81ed11509f7fb3d8e0925d 443 SUPERFAMILY SSF51338 362 435 4.71E-23 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS05905 810c63c10a81ed11509f7fb3d8e0925d 443 Gene3D G3DSA:3.20.20.140 89 379 1.8E-43 T 29-03-2018 SMALA_RS05905 810c63c10a81ed11509f7fb3d8e0925d 443 SUPERFAMILY SSF51556 72 363 1.57E-50 T 29-03-2018 IPR032466 Metal-dependent hydrolase SMALA_RS05905 810c63c10a81ed11509f7fb3d8e0925d 443 Pfam PF01979 Amidohydrolase family 69 409 2.5E-31 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 SMALA_RS03530 fb43579215b2ed2bdea9ffcfb5623a6f 488 Pfam PF00171 Aldehyde dehydrogenase family 15 475 3.7E-163 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS03530 fb43579215b2ed2bdea9ffcfb5623a6f 488 Gene3D G3DSA:3.40.605.10 1 263 6.5E-96 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS03530 fb43579215b2ed2bdea9ffcfb5623a6f 488 Gene3D G3DSA:3.40.309.10 264 461 2.2E-69 T 29-03-2018 SMALA_RS03530 fb43579215b2ed2bdea9ffcfb5623a6f 488 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 247 254 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 SMALA_RS03530 fb43579215b2ed2bdea9ffcfb5623a6f 488 SUPERFAMILY SSF53720 2 479 5.63E-162 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMALA_RS03530 fb43579215b2ed2bdea9ffcfb5623a6f 488 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 275 286 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 SMALA_RS03430 1429453ccc5b08fab09ac3eb34c66738 266 Pfam PF01427 D-ala-D-ala dipeptidase 38 161 1.6E-14 T 29-03-2018 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 SMALA_RS03430 1429453ccc5b08fab09ac3eb34c66738 266 Pfam PF01427 D-ala-D-ala dipeptidase 191 259 3.9E-12 T 29-03-2018 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 SMALA_RS03430 1429453ccc5b08fab09ac3eb34c66738 266 Gene3D G3DSA:3.30.1380.10 35 260 4.6E-69 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 SMALA_RS03430 1429453ccc5b08fab09ac3eb34c66738 266 Hamap MF_01924 D-alanyl-D-alanine dipeptidase [ddpX]. 38 258 31.602 T 29-03-2018 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 SMALA_RS03430 1429453ccc5b08fab09ac3eb34c66738 266 SUPERFAMILY SSF55166 36 259 1.33E-59 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 SMALA_RS03430 1429453ccc5b08fab09ac3eb34c66738 266 PIRSF PIRSF026671 9 264 7.1E-72 T 29-03-2018 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 SMALA_RS30935 63eb4b6806cf3af53ea239afc6ea29a0 277 Pfam PF04951 D-aminopeptidase 1 262 1.5E-91 T 29-03-2018 IPR007035 Peptidase M55, D-aminopeptidase SMALA_RS30935 63eb4b6806cf3af53ea239afc6ea29a0 277 SUPERFAMILY SSF63992 1 267 1.44E-82 T 29-03-2018 IPR007035 Peptidase M55, D-aminopeptidase SMALA_RS30935 63eb4b6806cf3af53ea239afc6ea29a0 277 Gene3D G3DSA:3.30.1360.130 208 269 2.4E-19 T 29-03-2018 SMALA_RS30935 63eb4b6806cf3af53ea239afc6ea29a0 277 Gene3D G3DSA:3.40.50.10780 1 207 5.1E-81 T 29-03-2018 IPR027476 D-aminopeptidase, N-terminal SMALA_RS30935 63eb4b6806cf3af53ea239afc6ea29a0 277 PIRSF PIRSF015853 1 274 5.2E-93 T 29-03-2018 IPR007035 Peptidase M55, D-aminopeptidase SMALA_RS11505 2ed8cbc611776c2c769dba4a783cb7ec 199 Pfam PF13023 HD domain 102 147 1.1E-6 T 29-03-2018 IPR006674 HD domain SMALA_RS11505 2ed8cbc611776c2c769dba4a783cb7ec 199 Pfam PF13023 HD domain 25 89 7.3E-14 T 29-03-2018 IPR006674 HD domain SMALA_RS11505 2ed8cbc611776c2c769dba4a783cb7ec 199 SUPERFAMILY SSF109604 17 146 1.33E-24 T 29-03-2018 SMALA_RS11505 2ed8cbc611776c2c769dba4a783cb7ec 199 SMART SM00471 40 149 6.1E-4 T 29-03-2018 IPR003607 HD/PDEase domain SMALA_RS11505 2ed8cbc611776c2c769dba4a783cb7ec 199 Gene3D G3DSA:1.10.3210.10 10 170 2.1E-27 T 29-03-2018 SMALA_RS20200 fdedcb1bbfed4ad572ba51eff7f3d0b9 512 Gene3D G3DSA:1.10.3260.10 62 177 1.1E-20 T 29-03-2018 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 SMALA_RS20200 fdedcb1bbfed4ad572ba51eff7f3d0b9 512 Gene3D G3DSA:1.10.3260.10 1 61 2.9E-4 T 29-03-2018 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 SMALA_RS20200 fdedcb1bbfed4ad572ba51eff7f3d0b9 512 ProSitePatterns PS00697 ATP-dependent DNA ligase AMP-binding site. 208 216 - T 29-03-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 SMALA_RS20200 fdedcb1bbfed4ad572ba51eff7f3d0b9 512 SUPERFAMILY SSF56091 180 385 2.06E-43 T 29-03-2018 SMALA_RS20200 fdedcb1bbfed4ad572ba51eff7f3d0b9 512 Gene3D G3DSA:2.40.50.140 385 511 1.8E-31 T 29-03-2018 SMALA_RS20200 fdedcb1bbfed4ad572ba51eff7f3d0b9 512 Pfam PF04675 DNA ligase N terminus 62 137 6.6E-7 T 29-03-2018 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 SMALA_RS20200 fdedcb1bbfed4ad572ba51eff7f3d0b9 512 TIGRFAM TIGR00574 dnl1: DNA ligase I, ATP-dependent (dnl1) 68 508 8.4E-77 T 29-03-2018 IPR000977 DNA ligase, ATP-dependent GO:0003910|GO:0005524|GO:0006281|GO:0006310|GO:0071897 SMALA_RS20200 fdedcb1bbfed4ad572ba51eff7f3d0b9 512 SUPERFAMILY SSF50249 387 509 1.61E-30 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMALA_RS20200 fdedcb1bbfed4ad572ba51eff7f3d0b9 512 SUPERFAMILY SSF117018 4 200 9.15E-27 T 29-03-2018 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 SMALA_RS20200 fdedcb1bbfed4ad572ba51eff7f3d0b9 512 Gene3D G3DSA:3.30.1490.70 326 384 1.1E-11 T 29-03-2018 SMALA_RS20200 fdedcb1bbfed4ad572ba51eff7f3d0b9 512 Hamap MF_00407 DNA ligase [lig]. 1 511 25.76 T 29-03-2018 IPR022865 DNA ligase, ATP-dependent, bacterial/archaeal GO:0003910 SMALA_RS20200 fdedcb1bbfed4ad572ba51eff7f3d0b9 512 Gene3D G3DSA:3.30.470.30 178 325 1.4E-31 T 29-03-2018 SMALA_RS20200 fdedcb1bbfed4ad572ba51eff7f3d0b9 512 Pfam PF04679 ATP dependent DNA ligase C terminal region 404 495 2.7E-13 T 29-03-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 SMALA_RS20200 fdedcb1bbfed4ad572ba51eff7f3d0b9 512 Pfam PF01068 ATP dependent DNA ligase domain 186 385 8.9E-43 T 29-03-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 SMALA_RS11805 9c8ca99e62d2033c1115f962af043c73 666 SUPERFAMILY SSF50998 16 346 3.3E-16 T 29-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily SMALA_RS11805 9c8ca99e62d2033c1115f962af043c73 666 Gene3D G3DSA:2.120.10.30 2 353 1.6E-21 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like SMALA_RS11805 9c8ca99e62d2033c1115f962af043c73 666 Pfam PF13360 PQQ-like domain 401 561 1.1E-4 T 29-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat SMALA_RS11805 9c8ca99e62d2033c1115f962af043c73 666 Gene3D G3DSA:2.130.10.10 385 645 8.0E-12 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMALA_RS11805 9c8ca99e62d2033c1115f962af043c73 666 SUPERFAMILY SSF69322 550 600 5.1E-25 T 29-03-2018 SMALA_RS11805 9c8ca99e62d2033c1115f962af043c73 666 SUPERFAMILY SSF69322 394 511 5.1E-25 T 29-03-2018 SMALA_RS11805 9c8ca99e62d2033c1115f962af043c73 666 SUPERFAMILY SSF69322 240 347 5.1E-25 T 29-03-2018 SMALA_RS06040 c21be789cc044d73f4425b807d63c338 319 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 111 305 3.1E-20 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS06040 c21be789cc044d73f4425b807d63c338 319 Gene3D G3DSA:1.20.58.370 23 64 7.1E-7 T 29-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain SMALA_RS06040 c21be789cc044d73f4425b807d63c338 319 Gene3D G3DSA:1.10.3720.10 86 316 8.0E-47 T 29-03-2018 SMALA_RS06040 c21be789cc044d73f4425b807d63c338 319 SUPERFAMILY SSF161098 78 306 3.14E-57 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS06040 c21be789cc044d73f4425b807d63c338 319 SUPERFAMILY SSF160964 30 64 1.7E-5 T 29-03-2018 SMALA_RS33105 38e9581ffcb44fc115e490f31d211dc9 1103 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 245 262 2.2E-63 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SMALA_RS33105 38e9581ffcb44fc115e490f31d211dc9 1103 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 303 332 2.2E-63 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SMALA_RS33105 38e9581ffcb44fc115e490f31d211dc9 1103 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 2.2E-63 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SMALA_RS33105 38e9581ffcb44fc115e490f31d211dc9 1103 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 2.2E-63 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SMALA_RS33105 38e9581ffcb44fc115e490f31d211dc9 1103 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 210 229 2.2E-63 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SMALA_RS33105 38e9581ffcb44fc115e490f31d211dc9 1103 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 385 403 2.2E-63 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SMALA_RS33105 38e9581ffcb44fc115e490f31d211dc9 1103 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 174 186 2.2E-63 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SMALA_RS33105 38e9581ffcb44fc115e490f31d211dc9 1103 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 680 877 1.8E-30 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SMALA_RS33105 38e9581ffcb44fc115e490f31d211dc9 1103 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 340 2.6E-66 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SMALA_RS33105 38e9581ffcb44fc115e490f31d211dc9 1103 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 170 184 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SMALA_RS33105 38e9581ffcb44fc115e490f31d211dc9 1103 Gene3D G3DSA:3.40.50.20 539 658 6.0E-58 T 29-03-2018 SMALA_RS33105 38e9581ffcb44fc115e490f31d211dc9 1103 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 713 727 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SMALA_RS33105 38e9581ffcb44fc115e490f31d211dc9 1103 SUPERFAMILY SSF52335 960 1094 1.44E-32 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain SMALA_RS33105 38e9581ffcb44fc115e490f31d211dc9 1103 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 303 310 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SMALA_RS33105 38e9581ffcb44fc115e490f31d211dc9 1103 Gene3D G3DSA:3.40.50.1380 954 1099 1.4E-42 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain SMALA_RS33105 38e9581ffcb44fc115e490f31d211dc9 1103 SUPERFAMILY SSF56059 128 406 1.38E-100 T 29-03-2018 SMALA_RS33105 38e9581ffcb44fc115e490f31d211dc9 1103 Gene3D G3DSA:3.40.50.20 4 117 1.1E-36 T 29-03-2018 SMALA_RS33105 38e9581ffcb44fc115e490f31d211dc9 1103 Gene3D G3DSA:3.30.470.20 752 953 2.5E-28 T 29-03-2018 SMALA_RS33105 38e9581ffcb44fc115e490f31d211dc9 1103 SUPERFAMILY SSF52440 2 127 7.48E-47 T 29-03-2018 IPR016185 Pre-ATP-grasp domain SMALA_RS33105 38e9581ffcb44fc115e490f31d211dc9 1103 Gene3D G3DSA:3.30.470.20 120 408 7.4E-64 T 29-03-2018 SMALA_RS33105 38e9581ffcb44fc115e490f31d211dc9 1103 Gene3D G3DSA:3.30.1490.20 659 751 1.1E-21 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SMALA_RS33105 38e9581ffcb44fc115e490f31d211dc9 1103 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1074 0.0 T 29-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SMALA_RS33105 38e9581ffcb44fc115e490f31d211dc9 1103 SMART SM01096 426 547 2.2E-57 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SMALA_RS33105 38e9581ffcb44fc115e490f31d211dc9 1103 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1086 12.954 T 29-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SMALA_RS33105 38e9581ffcb44fc115e490f31d211dc9 1103 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 431 547 5.2E-36 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SMALA_RS33105 38e9581ffcb44fc115e490f31d211dc9 1103 SMART SM00851 974 1065 3.1E-28 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain SMALA_RS33105 38e9581ffcb44fc115e490f31d211dc9 1103 Gene3D G3DSA:1.10.1030.10 409 538 6.2E-43 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SMALA_RS33105 38e9581ffcb44fc115e490f31d211dc9 1103 SUPERFAMILY SSF56059 678 951 1.63E-87 T 29-03-2018 SMALA_RS33105 38e9581ffcb44fc115e490f31d211dc9 1103 Pfam PF02142 MGS-like domain 975 1065 3.8E-21 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain SMALA_RS33105 38e9581ffcb44fc115e490f31d211dc9 1103 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 842 849 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SMALA_RS33105 38e9581ffcb44fc115e490f31d211dc9 1103 SUPERFAMILY SSF52440 558 678 1.04E-42 T 29-03-2018 IPR016185 Pre-ATP-grasp domain SMALA_RS33105 38e9581ffcb44fc115e490f31d211dc9 1103 SUPERFAMILY SSF48108 401 554 8.63E-46 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SMALA_RS18485 73a098ae66501a4aac9eae71966ab631 515 Pfam PF00561 alpha/beta hydrolase fold 104 487 4.5E-38 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS18485 73a098ae66501a4aac9eae71966ab631 515 SUPERFAMILY SSF53474 196 487 4.17E-23 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS18485 73a098ae66501a4aac9eae71966ab631 515 SUPERFAMILY SSF53474 91 153 4.17E-23 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS18485 73a098ae66501a4aac9eae71966ab631 515 Gene3D G3DSA:3.40.50.1820 9 504 1.9E-43 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS42080 cebcc023873c310278f2073ee5cc5125 693 SMART SM00382 305 445 0.0024 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS42080 cebcc023873c310278f2073ee5cc5125 693 SMART SM01043 102 247 1.6E-50 T 29-03-2018 IPR005158 Bacterial transcriptional activator domain SMALA_RS42080 cebcc023873c310278f2073ee5cc5125 693 SUPERFAMILY SSF46894 7 95 7.37E-11 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS42080 cebcc023873c310278f2073ee5cc5125 693 Gene3D G3DSA:1.10.10.10 1 98 6.6E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS42080 cebcc023873c310278f2073ee5cc5125 693 Gene3D G3DSA:1.25.40.10 100 272 5.2E-27 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS42080 cebcc023873c310278f2073ee5cc5125 693 SUPERFAMILY SSF48452 97 266 1.76E-37 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS42080 cebcc023873c310278f2073ee5cc5125 693 Pfam PF00486 Transcriptional regulatory protein, C terminal 28 95 1.0E-5 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS42080 cebcc023873c310278f2073ee5cc5125 693 Gene3D G3DSA:3.40.50.300 273 420 1.9E-13 T 29-03-2018 SMALA_RS42080 cebcc023873c310278f2073ee5cc5125 693 SMART SM00862 20 95 3.2E-4 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS42080 cebcc023873c310278f2073ee5cc5125 693 PRINTS PR00364 Disease resistance protein signature 308 323 5.2E-5 T 29-03-2018 SMALA_RS42080 cebcc023873c310278f2073ee5cc5125 693 PRINTS PR00364 Disease resistance protein signature 382 396 5.2E-5 T 29-03-2018 SMALA_RS42080 cebcc023873c310278f2073ee5cc5125 693 PRINTS PR00364 Disease resistance protein signature 467 481 5.2E-5 T 29-03-2018 SMALA_RS42080 cebcc023873c310278f2073ee5cc5125 693 Pfam PF00931 NB-ARC domain 298 492 3.7E-6 T 29-03-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207 SMALA_RS42080 cebcc023873c310278f2073ee5cc5125 693 SUPERFAMILY SSF52540 279 495 2.51E-20 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS42080 cebcc023873c310278f2073ee5cc5125 693 Pfam PF03704 Bacterial transcriptional activator domain 102 247 2.6E-44 T 29-03-2018 IPR005158 Bacterial transcriptional activator domain SMALA_RS15320 9806ac4010e6fe4c2e79374a7817a7e2 551 SUPERFAMILY SSF55545 7 141 6.93E-18 T 29-03-2018 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMALA_RS15320 9806ac4010e6fe4c2e79374a7817a7e2 551 Gene3D G3DSA:3.20.20.80 140 537 6.5E-139 T 29-03-2018 SMALA_RS15320 9806ac4010e6fe4c2e79374a7817a7e2 551 SUPERFAMILY SSF51445 142 510 3.88E-114 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS15320 9806ac4010e6fe4c2e79374a7817a7e2 551 Pfam PF02838 Glycosyl hydrolase family 20, domain 2 8 120 3.5E-17 T 29-03-2018 IPR015882 Beta-hexosaminidase, bacteial type, N-terminal KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822 SMALA_RS15320 9806ac4010e6fe4c2e79374a7817a7e2 551 Gene3D G3DSA:3.30.379.10 2 139 1.2E-23 T 29-03-2018 SMALA_RS15320 9806ac4010e6fe4c2e79374a7817a7e2 551 PRINTS PR00738 Glycosyl hydrolase family 20 signature 91 111 1.3E-35 T 29-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMALA_RS15320 9806ac4010e6fe4c2e79374a7817a7e2 551 PRINTS PR00738 Glycosyl hydrolase family 20 signature 476 493 1.3E-35 T 29-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMALA_RS15320 9806ac4010e6fe4c2e79374a7817a7e2 551 PRINTS PR00738 Glycosyl hydrolase family 20 signature 458 474 1.3E-35 T 29-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMALA_RS15320 9806ac4010e6fe4c2e79374a7817a7e2 551 PRINTS PR00738 Glycosyl hydrolase family 20 signature 165 186 1.3E-35 T 29-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMALA_RS15320 9806ac4010e6fe4c2e79374a7817a7e2 551 PRINTS PR00738 Glycosyl hydrolase family 20 signature 236 253 1.3E-35 T 29-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMALA_RS15320 9806ac4010e6fe4c2e79374a7817a7e2 551 PRINTS PR00738 Glycosyl hydrolase family 20 signature 309 322 1.3E-35 T 29-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMALA_RS15320 9806ac4010e6fe4c2e79374a7817a7e2 551 PRINTS PR00738 Glycosyl hydrolase family 20 signature 287 305 1.3E-35 T 29-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMALA_RS15320 9806ac4010e6fe4c2e79374a7817a7e2 551 Pfam PF00728 Glycosyl hydrolase family 20, catalytic domain 142 494 1.9E-121 T 29-03-2018 IPR015883 Glycoside hydrolase family 20, catalytic domain GO:0004553|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822 SMALA_RS15320 9806ac4010e6fe4c2e79374a7817a7e2 551 PIRSF PIRSF001093 69 537 1.9E-74 T 29-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMALA_RS37845 83a9bf3752b74590e459e7f28b5004b0 3453 SMART SM00825 Beta-ketoacyl synthase 1603 2029 1.6E-226 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS37845 83a9bf3752b74590e459e7f28b5004b0 3453 SMART SM00825 Beta-ketoacyl synthase 35 464 2.6E-221 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS37845 83a9bf3752b74590e459e7f28b5004b0 3453 SUPERFAMILY SSF55048 2267 2331 1.03E-11 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS37845 83a9bf3752b74590e459e7f28b5004b0 3453 SUPERFAMILY SSF51735 985 1200 1.06E-45 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS37845 83a9bf3752b74590e459e7f28b5004b0 3453 Pfam PF08990 Erythronolide synthase docking 2 24 2.1E-11 T 29-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 SMALA_RS37845 83a9bf3752b74590e459e7f28b5004b0 3453 SUPERFAMILY SSF51735 3010 3247 1.04E-47 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS37845 83a9bf3752b74590e459e7f28b5004b0 3453 Pfam PF00550 Phosphopantetheine attachment site 1502 1568 2.4E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS37845 83a9bf3752b74590e459e7f28b5004b0 3453 Pfam PF00550 Phosphopantetheine attachment site 3303 3368 4.3E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS37845 83a9bf3752b74590e459e7f28b5004b0 3453 Gene3D G3DSA:3.40.366.10 2322 2434 7.7E-30 T 29-03-2018 SMALA_RS37845 83a9bf3752b74590e459e7f28b5004b0 3453 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1981 2102 7.5E-14 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37845 83a9bf3752b74590e459e7f28b5004b0 3453 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 414 532 1.3E-16 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37845 83a9bf3752b74590e459e7f28b5004b0 3453 SUPERFAMILY SSF55048 694 759 2.22E-14 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS37845 83a9bf3752b74590e459e7f28b5004b0 3453 Gene3D G3DSA:3.40.47.10 1866 2027 4.6E-59 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS37845 83a9bf3752b74590e459e7f28b5004b0 3453 Gene3D G3DSA:3.40.47.10 301 462 4.4E-60 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS37845 83a9bf3752b74590e459e7f28b5004b0 3453 Gene3D G3DSA:1.10.1200.10 3271 3373 7.0E-20 T 29-03-2018 SMALA_RS37845 83a9bf3752b74590e459e7f28b5004b0 3453 SUPERFAMILY SSF47336 3294 3377 1.23E-22 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS37845 83a9bf3752b74590e459e7f28b5004b0 3453 SMART SM00823 Phosphopantetheine attachment site 3300 3372 1.2E-33 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37845 83a9bf3752b74590e459e7f28b5004b0 3453 SMART SM00823 Phosphopantetheine attachment site 1500 1572 4.3E-31 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37845 83a9bf3752b74590e459e7f28b5004b0 3453 Gene3D G3DSA:3.40.47.10 25 298 8.5E-87 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS37845 83a9bf3752b74590e459e7f28b5004b0 3453 Gene3D G3DSA:3.40.47.10 1599 1863 8.5E-87 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS37845 83a9bf3752b74590e459e7f28b5004b0 3453 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 570 868 1.0E-125 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS37845 83a9bf3752b74590e459e7f28b5004b0 3453 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2140 2444 8.0E-135 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS37845 83a9bf3752b74590e459e7f28b5004b0 3453 Gene3D G3DSA:3.10.129.10 2514 2637 1.5E-6 T 29-03-2018 SMALA_RS37845 83a9bf3752b74590e459e7f28b5004b0 3453 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1764 1780 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS37845 83a9bf3752b74590e459e7f28b5004b0 3453 SUPERFAMILY SSF53901 1597 1974 4.52E-101 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS37845 83a9bf3752b74590e459e7f28b5004b0 3453 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1527 1542 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS37845 83a9bf3752b74590e459e7f28b5004b0 3453 SMART SM01294 3301 3368 1.2E-5 T 29-03-2018 SMALA_RS37845 83a9bf3752b74590e459e7f28b5004b0 3453 SMART SM01294 1501 1568 5.4E-7 T 29-03-2018 SMALA_RS37845 83a9bf3752b74590e459e7f28b5004b0 3453 Gene3D G3DSA:3.40.366.10 567 708 2.3E-42 T 29-03-2018 SMALA_RS37845 83a9bf3752b74590e459e7f28b5004b0 3453 SUPERFAMILY SSF51735 2799 2996 3.02E-39 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS37845 83a9bf3752b74590e459e7f28b5004b0 3453 SMART SM00826 2512 2678 1.1E-82 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37845 83a9bf3752b74590e459e7f28b5004b0 3453 Gene3D G3DSA:3.30.70.250 2280 2321 1.7E-18 T 29-03-2018 SMALA_RS37845 83a9bf3752b74590e459e7f28b5004b0 3453 Gene3D G3DSA:3.30.70.250 709 754 6.6E-20 T 29-03-2018 SMALA_RS37845 83a9bf3752b74590e459e7f28b5004b0 3453 SUPERFAMILY SSF53901 30 154 2.73E-102 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS37845 83a9bf3752b74590e459e7f28b5004b0 3453 SUPERFAMILY SSF53901 182 408 2.73E-102 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS37845 83a9bf3752b74590e459e7f28b5004b0 3453 Pfam PF14765 Polyketide synthase dehydratase 2512 2787 4.8E-57 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37845 83a9bf3752b74590e459e7f28b5004b0 3453 Gene3D G3DSA:3.40.366.10 755 875 2.4E-29 T 29-03-2018 SMALA_RS37845 83a9bf3752b74590e459e7f28b5004b0 3453 Pfam PF00698 Acyl transferase domain 2139 2463 3.8E-65 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS37845 83a9bf3752b74590e459e7f28b5004b0 3453 Pfam PF00698 Acyl transferase domain 568 887 1.4E-93 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS37845 83a9bf3752b74590e459e7f28b5004b0 3453 SUPERFAMILY SSF52151 760 858 1.78E-69 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS37845 83a9bf3752b74590e459e7f28b5004b0 3453 SUPERFAMILY SSF52151 567 695 1.78E-69 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS37845 83a9bf3752b74590e459e7f28b5004b0 3453 Gene3D G3DSA:1.10.1200.10 1495 1598 1.5E-19 T 29-03-2018 SMALA_RS37845 83a9bf3752b74590e459e7f28b5004b0 3453 SUPERFAMILY SSF51735 1213 1441 3.98E-48 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS37845 83a9bf3752b74590e459e7f28b5004b0 3453 SUPERFAMILY SSF47336 1495 1616 1.13E-22 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS37845 83a9bf3752b74590e459e7f28b5004b0 3453 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 33 286 4.1E-93 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS37845 83a9bf3752b74590e459e7f28b5004b0 3453 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1601 1851 2.0E-93 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS37845 83a9bf3752b74590e459e7f28b5004b0 3453 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1859 1976 4.1E-43 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS37845 83a9bf3752b74590e459e7f28b5004b0 3453 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 294 411 6.2E-42 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS37845 83a9bf3752b74590e459e7f28b5004b0 3453 Gene3D G3DSA:3.40.366.10 2133 2279 2.0E-53 T 29-03-2018 SMALA_RS37845 83a9bf3752b74590e459e7f28b5004b0 3453 Pfam PF08659 KR domain 3013 3191 1.5E-60 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37845 83a9bf3752b74590e459e7f28b5004b0 3453 Pfam PF08659 KR domain 1215 1392 3.7E-58 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37845 83a9bf3752b74590e459e7f28b5004b0 3453 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3327 3342 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS37845 83a9bf3752b74590e459e7f28b5004b0 3453 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1215 1394 7.1E-59 T 29-03-2018 SMALA_RS37845 83a9bf3752b74590e459e7f28b5004b0 3453 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3013 3193 1.5E-65 T 29-03-2018 SMALA_RS37845 83a9bf3752b74590e459e7f28b5004b0 3453 SUPERFAMILY SSF52151 2332 2428 7.59E-78 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS37845 83a9bf3752b74590e459e7f28b5004b0 3453 SUPERFAMILY SSF52151 2136 2268 7.59E-78 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS37845 83a9bf3752b74590e459e7f28b5004b0 3453 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 199 215 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS37845 83a9bf3752b74590e459e7f28b5004b0 3453 Gene3D G3DSA:3.40.50.720 3005 3268 2.9E-52 T 29-03-2018 SMALA_RS37845 83a9bf3752b74590e459e7f28b5004b0 3453 Gene3D G3DSA:3.40.50.720 1208 1466 6.8E-53 T 29-03-2018 SMALA_RS03015 7c0d4d9cc2aa761df2cdb35db3486f07 78 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 71 20.49 T 29-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS03015 7c0d4d9cc2aa761df2cdb35db3486f07 78 Gene3D G3DSA:2.30.170.40 2 75 1.0E-26 T 29-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS03015 7c0d4d9cc2aa761df2cdb35db3486f07 78 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 58 1.1E-26 T 29-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS03015 7c0d4d9cc2aa761df2cdb35db3486f07 78 SUPERFAMILY SSF143800 2 76 7.65E-27 T 29-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS03015 7c0d4d9cc2aa761df2cdb35db3486f07 78 Pfam PF00830 Ribosomal L28 family 4 60 6.5E-25 T 29-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS02325 411c763c2c33720aa1748912bccebcdd 226 Gene3D G3DSA:2.60.120.590 8 217 1.1E-44 T 29-03-2018 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like SMALA_RS02325 411c763c2c33720aa1748912bccebcdd 226 SUPERFAMILY SSF51197 13 214 2.88E-42 T 29-03-2018 SMALA_RS02325 411c763c2c33720aa1748912bccebcdd 226 Pfam PF13532 2OG-Fe(II) oxygenase superfamily 15 213 3.7E-49 T 29-03-2018 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like SMALA_RS38880 bb97d08c894c05581d5f6ee1e4b13ebc 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 139 7.3E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS38880 bb97d08c894c05581d5f6ee1e4b13ebc 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 7.3E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS38880 bb97d08c894c05581d5f6ee1e4b13ebc 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 7.3E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS38880 bb97d08c894c05581d5f6ee1e4b13ebc 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 7.3E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS38880 bb97d08c894c05581d5f6ee1e4b13ebc 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 168 7.3E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS38880 bb97d08c894c05581d5f6ee1e4b13ebc 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 220 240 7.3E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS38880 bb97d08c894c05581d5f6ee1e4b13ebc 260 SUPERFAMILY SSF51735 7 256 4.35E-66 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS38880 bb97d08c894c05581d5f6ee1e4b13ebc 260 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 255 2.0E-49 T 29-03-2018 SMALA_RS38880 bb97d08c894c05581d5f6ee1e4b13ebc 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 129 137 8.8E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS38880 bb97d08c894c05581d5f6ee1e4b13ebc 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 168 8.8E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS38880 bb97d08c894c05581d5f6ee1e4b13ebc 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 8.8E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS38880 bb97d08c894c05581d5f6ee1e4b13ebc 260 Gene3D G3DSA:3.40.50.720 46 259 6.3E-52 T 29-03-2018 SMALA_RS38880 bb97d08c894c05581d5f6ee1e4b13ebc 260 Gene3D G3DSA:3.40.50.720 1 45 1.2E-9 T 29-03-2018 SMALA_RS38880 bb97d08c894c05581d5f6ee1e4b13ebc 260 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 136 164 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMALA_RS14135 ebc08d2e07889e0ca31f0259a9b27b56 307 Pfam PF06259 Alpha/beta hydrolase 91 252 4.1E-41 T 29-03-2018 IPR010427 Protein of unknown function DUF1023 SMALA_RS14135 ebc08d2e07889e0ca31f0259a9b27b56 307 Gene3D G3DSA:3.40.50.1820 102 306 1.2E-20 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS14135 ebc08d2e07889e0ca31f0259a9b27b56 307 SUPERFAMILY SSF53474 113 291 2.84E-6 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS07335 bae37563fe33004470b8b715c608fac7 534 Gene3D G3DSA:3.10.105.10 307 503 5.0E-47 T 29-03-2018 SMALA_RS07335 bae37563fe33004470b8b715c608fac7 534 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 84 445 6.8E-75 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain SMALA_RS07335 bae37563fe33004470b8b715c608fac7 534 Gene3D G3DSA:3.40.190.10 167 306 1.9E-26 T 29-03-2018 SMALA_RS07335 bae37563fe33004470b8b715c608fac7 534 Gene3D G3DSA:3.90.76.10 59 166 7.1E-26 T 29-03-2018 SMALA_RS07335 bae37563fe33004470b8b715c608fac7 534 PIRSF PIRSF002741 4 534 4.9E-85 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 SMALA_RS07335 bae37563fe33004470b8b715c608fac7 534 SUPERFAMILY SSF53850 37 533 6.86E-113 T 29-03-2018 SMALA_RS29675 3064a9ca246b197db34ce9efa4de3551 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 20 250 3.1E-62 T 29-03-2018 SMALA_RS29675 3064a9ca246b197db34ce9efa4de3551 256 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 14 203 3.3E-4 T 29-03-2018 SMALA_RS29675 3064a9ca246b197db34ce9efa4de3551 256 SUPERFAMILY SSF51735 15 251 3.97E-75 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS29675 3064a9ca246b197db34ce9efa4de3551 256 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 147 175 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMALA_RS29675 3064a9ca246b197db34ce9efa4de3551 256 Gene3D G3DSA:3.40.50.720 49 256 3.6E-60 T 29-03-2018 SMALA_RS29675 3064a9ca246b197db34ce9efa4de3551 256 Gene3D G3DSA:3.40.50.720 8 48 9.0E-10 T 29-03-2018 SMALA_RS29675 3064a9ca246b197db34ce9efa4de3551 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 148 7.9E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS29675 3064a9ca246b197db34ce9efa4de3551 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 7.9E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS29675 3064a9ca246b197db34ce9efa4de3551 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 88 99 7.9E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS29675 3064a9ca246b197db34ce9efa4de3551 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 15 32 1.8E-34 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS29675 3064a9ca246b197db34ce9efa4de3551 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 1.8E-34 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS29675 3064a9ca246b197db34ce9efa4de3551 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 1.8E-34 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS29675 3064a9ca246b197db34ce9efa4de3551 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 1.8E-34 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS29675 3064a9ca246b197db34ce9efa4de3551 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 1.8E-34 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS29675 3064a9ca246b197db34ce9efa4de3551 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 1.8E-34 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS00385 d19c77a2d45431448127c12cabab6b86 104 SUPERFAMILY SSF47336 3 73 3.4E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS00385 d19c77a2d45431448127c12cabab6b86 104 Pfam PF00550 Phosphopantetheine attachment site 2 64 3.7E-6 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS00385 d19c77a2d45431448127c12cabab6b86 104 Gene3D G3DSA:1.10.1200.10 1 80 7.1E-12 T 29-03-2018 SMALA_RS39695 042d3f876c63f4732106677a201d26e3 291 Pfam PF00582 Universal stress protein family 1 136 6.5E-27 T 29-03-2018 IPR006016 UspA GO:0006950 SMALA_RS39695 042d3f876c63f4732106677a201d26e3 291 Pfam PF00582 Universal stress protein family 152 289 5.0E-12 T 29-03-2018 IPR006016 UspA GO:0006950 SMALA_RS39695 042d3f876c63f4732106677a201d26e3 291 SUPERFAMILY SSF52402 3 138 2.43E-30 T 29-03-2018 SMALA_RS39695 042d3f876c63f4732106677a201d26e3 291 Gene3D G3DSA:3.40.50.620 148 291 5.7E-20 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS39695 042d3f876c63f4732106677a201d26e3 291 SUPERFAMILY SSF52402 164 290 3.1E-20 T 29-03-2018 SMALA_RS39695 042d3f876c63f4732106677a201d26e3 291 PRINTS PR01438 Universal stress protein signature 2 20 5.5E-16 T 29-03-2018 IPR006015 Universal stress protein A SMALA_RS39695 042d3f876c63f4732106677a201d26e3 291 PRINTS PR01438 Universal stress protein signature 114 136 5.5E-16 T 29-03-2018 IPR006015 Universal stress protein A SMALA_RS39695 042d3f876c63f4732106677a201d26e3 291 PRINTS PR01438 Universal stress protein signature 96 108 5.5E-16 T 29-03-2018 IPR006015 Universal stress protein A SMALA_RS39695 042d3f876c63f4732106677a201d26e3 291 Gene3D G3DSA:3.40.50.620 1 147 2.2E-35 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS14920 bd2cb0dba704ac3baf5c5022805d4d9c 161 Pfam PF03928 Haem-degrading 26 154 1.5E-32 T 29-03-2018 IPR005624 Haem-degrading SMALA_RS14920 bd2cb0dba704ac3baf5c5022805d4d9c 161 SUPERFAMILY SSF143744 18 156 2.48E-27 T 29-03-2018 SMALA_RS14920 bd2cb0dba704ac3baf5c5022805d4d9c 161 PIRSF PIRSF008757 1 161 4.6E-60 T 29-03-2018 IPR010371 Uncharacterised protein family UPF0303 SMALA_RS14920 bd2cb0dba704ac3baf5c5022805d4d9c 161 Hamap MF_00761 UPF0303 protein . 4 159 33.649 T 29-03-2018 IPR010371 Uncharacterised protein family UPF0303 SMALA_RS23515 d0f343a2ef1896ec06c66d5bb9b09829 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 3.2E-23 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS23515 d0f343a2ef1896ec06c66d5bb9b09829 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 3.2E-23 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS23515 d0f343a2ef1896ec06c66d5bb9b09829 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 3.2E-23 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS23515 d0f343a2ef1896ec06c66d5bb9b09829 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 3.2E-23 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS23515 d0f343a2ef1896ec06c66d5bb9b09829 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 3.2E-23 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS23515 d0f343a2ef1896ec06c66d5bb9b09829 245 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 187 8.7E-6 T 29-03-2018 SMALA_RS23515 d0f343a2ef1896ec06c66d5bb9b09829 245 SUPERFAMILY SSF51735 1 229 1.11E-66 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS23515 d0f343a2ef1896ec06c66d5bb9b09829 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 9.3E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS23515 d0f343a2ef1896ec06c66d5bb9b09829 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 9.3E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS23515 d0f343a2ef1896ec06c66d5bb9b09829 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 9.3E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS23515 d0f343a2ef1896ec06c66d5bb9b09829 245 Pfam PF00106 short chain dehydrogenase 7 194 6.2E-55 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS23515 d0f343a2ef1896ec06c66d5bb9b09829 245 Gene3D G3DSA:3.40.50.720 165 233 3.6E-7 T 29-03-2018 SMALA_RS23515 d0f343a2ef1896ec06c66d5bb9b09829 245 Gene3D G3DSA:3.40.50.720 2 164 9.5E-50 T 29-03-2018 SMALA_RS16490 7fc0ac7a2bae0bd260af50ba5e22ddb0 295 Gene3D G3DSA:1.10.10.10 4 84 1.9E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS16490 7fc0ac7a2bae0bd260af50ba5e22ddb0 295 SUPERFAMILY SSF46785 6 85 1.06E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS16490 7fc0ac7a2bae0bd260af50ba5e22ddb0 295 Gene3D G3DSA:3.40.190.10 90 176 7.0E-23 T 29-03-2018 SMALA_RS16490 7fc0ac7a2bae0bd260af50ba5e22ddb0 295 Pfam PF03466 LysR substrate binding domain 89 289 5.9E-47 T 29-03-2018 IPR005119 LysR, substrate-binding SMALA_RS16490 7fc0ac7a2bae0bd260af50ba5e22ddb0 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 2.8E-19 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS16490 7fc0ac7a2bae0bd260af50ba5e22ddb0 295 SUPERFAMILY SSF53850 89 293 5.32E-41 T 29-03-2018 SMALA_RS16490 7fc0ac7a2bae0bd260af50ba5e22ddb0 295 Gene3D G3DSA:3.40.190.10 177 264 1.3E-25 T 29-03-2018 SMALA_RS16490 7fc0ac7a2bae0bd260af50ba5e22ddb0 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 1.3E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS16490 7fc0ac7a2bae0bd260af50ba5e22ddb0 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 1.3E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS16490 7fc0ac7a2bae0bd260af50ba5e22ddb0 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 1.3E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS14565 98cff2a6b9c5a4879519c10125b7c86e 624 Pfam PF04185 Phosphoesterase family 51 512 2.8E-79 T 29-03-2018 IPR007312 Phosphoesterase GO:0016788 SMALA_RS14565 98cff2a6b9c5a4879519c10125b7c86e 624 Gene3D G3DSA:3.40.720.10 46 512 7.1E-13 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 SMALA_RS37905 07e1a298654bc22050a0448ea07f7e06 298 Pfam PF00106 short chain dehydrogenase 22 212 1.8E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS37905 07e1a298654bc22050a0448ea07f7e06 298 Gene3D G3DSA:3.40.50.720 6 297 7.1E-58 T 29-03-2018 SMALA_RS37905 07e1a298654bc22050a0448ea07f7e06 298 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 189 6.6E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS37905 07e1a298654bc22050a0448ea07f7e06 298 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 193 210 6.6E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS37905 07e1a298654bc22050a0448ea07f7e06 298 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 6.6E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS37905 07e1a298654bc22050a0448ea07f7e06 298 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 22 39 6.6E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS37905 07e1a298654bc22050a0448ea07f7e06 298 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 90 101 6.6E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS37905 07e1a298654bc22050a0448ea07f7e06 298 SUPERFAMILY SSF51735 19 243 5.91E-49 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS18300 d3aa43df8c760728522fa6bc4b5a15d4 635 Gene3D G3DSA:3.30.450.20 272 421 1.2E-26 T 29-03-2018 SMALA_RS18300 d3aa43df8c760728522fa6bc4b5a15d4 635 SUPERFAMILY SSF55874 521 615 2.58E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS18300 d3aa43df8c760728522fa6bc4b5a15d4 635 SMART SM00091 273 339 3.4E-9 T 29-03-2018 IPR000014 PAS domain SMALA_RS18300 d3aa43df8c760728522fa6bc4b5a15d4 635 SMART SM00091 161 227 1.4E-8 T 29-03-2018 IPR000014 PAS domain SMALA_RS18300 d3aa43df8c760728522fa6bc4b5a15d4 635 Gene3D G3DSA:3.30.450.20 145 271 1.8E-16 T 29-03-2018 SMALA_RS18300 d3aa43df8c760728522fa6bc4b5a15d4 635 Pfam PF00072 Response regulator receiver domain 8 119 9.7E-20 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS18300 d3aa43df8c760728522fa6bc4b5a15d4 635 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 528 616 9.2E-6 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS18300 d3aa43df8c760728522fa6bc4b5a15d4 635 Pfam PF13426 PAS domain 171 265 5.1E-11 T 29-03-2018 IPR000014 PAS domain SMALA_RS18300 d3aa43df8c760728522fa6bc4b5a15d4 635 Gene3D G3DSA:3.30.565.10 482 621 2.7E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS18300 d3aa43df8c760728522fa6bc4b5a15d4 635 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 270 389 2.0E-23 T 29-03-2018 IPR000014 PAS domain SMALA_RS18300 d3aa43df8c760728522fa6bc4b5a15d4 635 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 160 272 6.6E-14 T 29-03-2018 IPR000014 PAS domain SMALA_RS18300 d3aa43df8c760728522fa6bc4b5a15d4 635 SMART SM00448 6 119 7.4E-21 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS18300 d3aa43df8c760728522fa6bc4b5a15d4 635 Pfam PF07730 Histidine kinase 420 485 5.5E-10 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMALA_RS18300 d3aa43df8c760728522fa6bc4b5a15d4 635 Gene3D G3DSA:3.40.50.2300 5 144 2.4E-28 T 29-03-2018 SMALA_RS18300 d3aa43df8c760728522fa6bc4b5a15d4 635 Pfam PF08448 PAS fold 280 387 4.0E-12 T 29-03-2018 IPR013656 PAS fold-4 SMALA_RS18300 d3aa43df8c760728522fa6bc4b5a15d4 635 SMART SM00387 522 617 1.6E-4 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS18300 d3aa43df8c760728522fa6bc4b5a15d4 635 SUPERFAMILY SSF55785 267 383 6.15E-24 T 29-03-2018 IPR000014 PAS domain SMALA_RS18300 d3aa43df8c760728522fa6bc4b5a15d4 635 SUPERFAMILY SSF52172 5 129 1.32E-27 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS18300 d3aa43df8c760728522fa6bc4b5a15d4 635 SUPERFAMILY SSF55785 173 277 7.99E-15 T 29-03-2018 IPR000014 PAS domain SMALA_RS01195 c000b74f6aea3d7cdbd3e3e6b2c9fa89 263 Pfam PF08242 Methyltransferase domain 98 199 2.6E-14 T 29-03-2018 IPR013217 Methyltransferase type 12 SMALA_RS01195 c000b74f6aea3d7cdbd3e3e6b2c9fa89 263 Gene3D G3DSA:3.40.50.150 7 257 2.6E-22 T 29-03-2018 SMALA_RS01195 c000b74f6aea3d7cdbd3e3e6b2c9fa89 263 SUPERFAMILY SSF53335 74 236 9.45E-24 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS29820 bff91ed5b68c1ccc7f4dd9bb5945b43f 709 SUPERFAMILY SSF51735 337 522 8.16E-53 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS29820 bff91ed5b68c1ccc7f4dd9bb5945b43f 709 Pfam PF00378 Enoyl-CoA hydratase/isomerase 54 236 7.1E-19 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 SMALA_RS29820 bff91ed5b68c1ccc7f4dd9bb5945b43f 709 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 340 520 1.9E-58 T 29-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 SMALA_RS29820 bff91ed5b68c1ccc7f4dd9bb5945b43f 709 Gene3D G3DSA:3.90.226.10 17 295 6.1E-34 T 29-03-2018 SMALA_RS29820 bff91ed5b68c1ccc7f4dd9bb5945b43f 709 SUPERFAMILY SSF48179 522 615 3.15E-17 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMALA_RS29820 bff91ed5b68c1ccc7f4dd9bb5945b43f 709 SUPERFAMILY SSF52096 253 326 1.18E-34 T 29-03-2018 IPR029045 ClpP/crotonase-like domain SMALA_RS29820 bff91ed5b68c1ccc7f4dd9bb5945b43f 709 SUPERFAMILY SSF52096 34 220 1.18E-34 T 29-03-2018 IPR029045 ClpP/crotonase-like domain SMALA_RS29820 bff91ed5b68c1ccc7f4dd9bb5945b43f 709 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 524 606 1.1E-11 T 29-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 SMALA_RS29820 bff91ed5b68c1ccc7f4dd9bb5945b43f 709 Gene3D G3DSA:1.10.1040.10 632 700 1.9E-6 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMALA_RS29820 bff91ed5b68c1ccc7f4dd9bb5945b43f 709 Gene3D G3DSA:3.40.50.720 296 522 1.3E-54 T 29-03-2018 SMALA_RS29820 bff91ed5b68c1ccc7f4dd9bb5945b43f 709 Gene3D G3DSA:1.10.1040.10 523 610 4.6E-13 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMALA_RS29820 bff91ed5b68c1ccc7f4dd9bb5945b43f 709 SUPERFAMILY SSF48179 634 695 5.02E-10 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMALA_RS34245 5da438cc823f33d3060a9e9954e941f7 436 Pfam PF02056 Family 4 glycosyl hydrolase 5 186 2.0E-55 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SMALA_RS34245 5da438cc823f33d3060a9e9954e941f7 436 SUPERFAMILY SSF56327 170 428 2.45E-65 T 29-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 SMALA_RS34245 5da438cc823f33d3060a9e9954e941f7 436 PRINTS PR00732 Glycosyl hydrolase family 4 signature 111 131 2.5E-32 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SMALA_RS34245 5da438cc823f33d3060a9e9954e941f7 436 PRINTS PR00732 Glycosyl hydrolase family 4 signature 192 204 2.5E-32 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SMALA_RS34245 5da438cc823f33d3060a9e9954e941f7 436 PRINTS PR00732 Glycosyl hydrolase family 4 signature 166 177 2.5E-32 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SMALA_RS34245 5da438cc823f33d3060a9e9954e941f7 436 PRINTS PR00732 Glycosyl hydrolase family 4 signature 95 108 2.5E-32 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SMALA_RS34245 5da438cc823f33d3060a9e9954e941f7 436 PRINTS PR00732 Glycosyl hydrolase family 4 signature 140 157 2.5E-32 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SMALA_RS34245 5da438cc823f33d3060a9e9954e941f7 436 PRINTS PR00732 Glycosyl hydrolase family 4 signature 74 90 2.5E-32 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SMALA_RS34245 5da438cc823f33d3060a9e9954e941f7 436 PRINTS PR00732 Glycosyl hydrolase family 4 signature 5 20 2.5E-32 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SMALA_RS34245 5da438cc823f33d3060a9e9954e941f7 436 Gene3D G3DSA:3.90.1820.10 1 288 5.6E-72 T 29-03-2018 SMALA_RS34245 5da438cc823f33d3060a9e9954e941f7 436 Gene3D G3DSA:3.90.1820.10 289 433 6.3E-34 T 29-03-2018 SMALA_RS34245 5da438cc823f33d3060a9e9954e941f7 436 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 196 402 1.7E-59 T 29-03-2018 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 SMALA_RS34245 5da438cc823f33d3060a9e9954e941f7 436 SUPERFAMILY SSF51735 4 167 3.23E-48 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS10570 059c0a4d56b71168ef9d7d922e282e6d 469 PIRSF PIRSF005572 1 376 1.1E-127 T 29-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 SMALA_RS10570 059c0a4d56b71168ef9d7d922e282e6d 469 Pfam PF00266 Aminotransferase class-V 3 361 3.8E-38 T 29-03-2018 IPR000192 Aminotransferase class V domain SMALA_RS10570 059c0a4d56b71168ef9d7d922e282e6d 469 SUPERFAMILY SSF64307 393 467 6.8E-17 T 29-03-2018 IPR001455 TusA-like domain SMALA_RS10570 059c0a4d56b71168ef9d7d922e282e6d 469 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 400 424 - T 29-03-2018 IPR001455 TusA-like domain SMALA_RS10570 059c0a4d56b71168ef9d7d922e282e6d 469 Gene3D G3DSA:3.90.1150.10 261 376 2.0E-36 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS10570 059c0a4d56b71168ef9d7d922e282e6d 469 SUPERFAMILY SSF53383 3 369 1.67E-73 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS10570 059c0a4d56b71168ef9d7d922e282e6d 469 Gene3D G3DSA:3.30.110.40 391 468 1.4E-16 T 29-03-2018 IPR001455 TusA-like domain SMALA_RS10570 059c0a4d56b71168ef9d7d922e282e6d 469 Gene3D G3DSA:3.40.640.10 10 254 2.6E-41 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS10570 059c0a4d56b71168ef9d7d922e282e6d 469 Pfam PF01206 Sulfurtransferase TusA 399 467 1.7E-13 T 29-03-2018 IPR001455 TusA-like domain SMALA_RS22525 520297906aedafa3bf310fd703d0279c 329 SUPERFAMILY SSF55729 8 177 3.78E-16 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS22525 520297906aedafa3bf310fd703d0279c 329 Gene3D G3DSA:3.40.630.30 6 181 7.7E-17 T 29-03-2018 SMALA_RS22525 520297906aedafa3bf310fd703d0279c 329 Pfam PF00583 Acetyltransferase (GNAT) family 56 158 5.4E-7 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SMALA_RS28495 14102ab2ead59ac2925dd35734a409b1 317 Pfam PF06574 FAD synthetase 12 159 9.4E-50 T 29-03-2018 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 SMALA_RS28495 14102ab2ead59ac2925dd35734a409b1 317 SUPERFAMILY SSF52374 16 179 1.24E-33 T 29-03-2018 SMALA_RS28495 14102ab2ead59ac2925dd35734a409b1 317 SUPERFAMILY SSF82114 178 313 1.48E-42 T 29-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 SMALA_RS28495 14102ab2ead59ac2925dd35734a409b1 317 Gene3D G3DSA:2.40.30.30 184 317 2.5E-43 T 29-03-2018 IPR023465 Riboflavin kinase domain GO:0008531|GO:0009231 Reactome: R-HSA-196843 SMALA_RS28495 14102ab2ead59ac2925dd35734a409b1 317 Gene3D G3DSA:3.40.50.620 1 183 1.9E-48 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS28495 14102ab2ead59ac2925dd35734a409b1 317 PIRSF PIRSF004491 1 317 1.9E-97 T 29-03-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 SMALA_RS28495 14102ab2ead59ac2925dd35734a409b1 317 SMART SM00904 187 312 6.5E-50 T 29-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 SMALA_RS28495 14102ab2ead59ac2925dd35734a409b1 317 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 19 311 9.4E-65 T 29-03-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 SMALA_RS28495 14102ab2ead59ac2925dd35734a409b1 317 Pfam PF01687 Riboflavin kinase 188 310 8.9E-34 T 29-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 SMALA_RS27070 3a2ff1b80d6ac00039b7ca52ae5cca6f 464 SUPERFAMILY SSF55874 305 462 9.95E-35 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS27070 3a2ff1b80d6ac00039b7ca52ae5cca6f 464 Gene3D G3DSA:3.30.565.10 300 464 7.3E-39 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS27070 3a2ff1b80d6ac00039b7ca52ae5cca6f 464 SUPERFAMILY SSF47384 237 316 1.12E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS27070 3a2ff1b80d6ac00039b7ca52ae5cca6f 464 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 357 462 2.3E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS27070 3a2ff1b80d6ac00039b7ca52ae5cca6f 464 SMART SM00388 254 315 1.4E-10 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS27070 3a2ff1b80d6ac00039b7ca52ae5cca6f 464 Pfam PF00512 His Kinase A (phospho-acceptor) domain 255 315 5.5E-8 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS27070 3a2ff1b80d6ac00039b7ca52ae5cca6f 464 Gene3D G3DSA:1.10.287.130 259 299 9.0E-9 T 29-03-2018 SMALA_RS27070 3a2ff1b80d6ac00039b7ca52ae5cca6f 464 PRINTS PR00344 Bacterial sensor protein C-terminal signature 408 418 7.5E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS27070 3a2ff1b80d6ac00039b7ca52ae5cca6f 464 PRINTS PR00344 Bacterial sensor protein C-terminal signature 390 404 7.5E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS27070 3a2ff1b80d6ac00039b7ca52ae5cca6f 464 PRINTS PR00344 Bacterial sensor protein C-terminal signature 425 443 7.5E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS27070 3a2ff1b80d6ac00039b7ca52ae5cca6f 464 PRINTS PR00344 Bacterial sensor protein C-terminal signature 449 462 7.5E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS27070 3a2ff1b80d6ac00039b7ca52ae5cca6f 464 Gene3D G3DSA:3.30.450.20 71 258 0.0091 T 29-03-2018 SMALA_RS27070 3a2ff1b80d6ac00039b7ca52ae5cca6f 464 SMART SM00387 355 464 2.0E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS27070 3a2ff1b80d6ac00039b7ca52ae5cca6f 464 SMART SM00304 199 253 3.3E-5 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMALA_RS18835 f71b959fbc549cec4f6322da12b8a339 78 Gene3D G3DSA:1.10.10.10 21 78 3.3E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS18835 f71b959fbc549cec4f6322da12b8a339 78 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 21 68 3.6E-14 T 29-03-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 SMALA_RS18835 f71b959fbc549cec4f6322da12b8a339 78 Pfam PF12728 Helix-turn-helix domain 21 69 4.0E-7 T 29-03-2018 SMALA_RS03100 7ae77f3386e8d201f100fbd912129b38 321 Gene3D G3DSA:3.30.360.10 133 301 1.6E-13 T 29-03-2018 SMALA_RS03100 7ae77f3386e8d201f100fbd912129b38 321 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 1 121 4.4E-16 T 29-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 SMALA_RS03100 7ae77f3386e8d201f100fbd912129b38 321 SUPERFAMILY SSF55347 123 258 2.94E-33 T 29-03-2018 SMALA_RS03100 7ae77f3386e8d201f100fbd912129b38 321 Gene3D G3DSA:3.40.50.720 1 132 1.4E-30 T 29-03-2018 SMALA_RS03100 7ae77f3386e8d201f100fbd912129b38 321 SUPERFAMILY SSF51735 1 137 1.12E-34 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS27230 ca8642234dfca53a6973c6156d3bbb81 487 Gene3D G3DSA:3.50.50.60 2 399 9.9E-61 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS27230 ca8642234dfca53a6973c6156d3bbb81 487 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 147 162 2.8E-40 T 29-03-2018 SMALA_RS27230 ca8642234dfca53a6973c6156d3bbb81 487 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 304 320 2.8E-40 T 29-03-2018 SMALA_RS27230 ca8642234dfca53a6973c6156d3bbb81 487 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 340 356 2.8E-40 T 29-03-2018 SMALA_RS27230 ca8642234dfca53a6973c6156d3bbb81 487 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 289 304 2.8E-40 T 29-03-2018 SMALA_RS27230 ca8642234dfca53a6973c6156d3bbb81 487 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 2.8E-40 T 29-03-2018 SMALA_RS27230 ca8642234dfca53a6973c6156d3bbb81 487 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 322 340 2.8E-40 T 29-03-2018 SMALA_RS27230 ca8642234dfca53a6973c6156d3bbb81 487 SUPERFAMILY SSF51905 2 168 2.39E-60 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS27230 ca8642234dfca53a6973c6156d3bbb81 487 SUPERFAMILY SSF51905 276 365 2.39E-60 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS27230 ca8642234dfca53a6973c6156d3bbb81 487 Pfam PF01494 FAD binding domain 2 353 2.5E-69 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 SMALA_RS34020 3bb2da17207b712acac3591b41954934 1157 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 301 415 5.6E-32 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS34020 3bb2da17207b712acac3591b41954934 1157 Gene3D G3DSA:3.40.47.10 308 465 1.7E-44 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS34020 3bb2da17207b712acac3591b41954934 1157 SMART SM00825 Beta-ketoacyl synthase 21 465 5.1E-98 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS34020 3bb2da17207b712acac3591b41954934 1157 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 19 293 2.1E-62 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS34020 3bb2da17207b712acac3591b41954934 1157 Gene3D G3DSA:3.90.1150.10 1045 1155 1.2E-20 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS34020 3bb2da17207b712acac3591b41954934 1157 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 422 517 2.2E-14 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS34020 3bb2da17207b712acac3591b41954934 1157 Gene3D G3DSA:3.40.47.10 11 305 1.1E-69 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS34020 3bb2da17207b712acac3591b41954934 1157 SUPERFAMILY SSF53901 17 138 7.46E-71 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS34020 3bb2da17207b712acac3591b41954934 1157 SUPERFAMILY SSF53901 442 462 7.46E-71 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS34020 3bb2da17207b712acac3591b41954934 1157 SUPERFAMILY SSF53901 189 411 7.46E-71 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS34020 3bb2da17207b712acac3591b41954934 1157 Pfam PF00155 Aminotransferase class I and II 805 1144 1.8E-40 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMALA_RS34020 3bb2da17207b712acac3591b41954934 1157 Gene3D G3DSA:3.40.640.10 819 1044 2.5E-48 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS34020 3bb2da17207b712acac3591b41954934 1157 SUPERFAMILY SSF47336 672 750 4.32E-6 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS34020 3bb2da17207b712acac3591b41954934 1157 SUPERFAMILY SSF53383 797 1150 6.8E-97 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS07310 3a03e0d5a41be39a7eed77170fc0627a 1168 PIRSF PIRSF000381 10 1168 0.0 T 29-03-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMALA_RS07310 3a03e0d5a41be39a7eed77170fc0627a 1168 Pfam PF02310 B12 binding domain 734 850 4.5E-20 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 SMALA_RS07310 3a03e0d5a41be39a7eed77170fc0627a 1168 Gene3D G3DSA:3.20.20.20 336 633 1.7E-48 T 29-03-2018 SMALA_RS07310 3a03e0d5a41be39a7eed77170fc0627a 1168 Gene3D G3DSA:3.10.196.10 1058 1168 6.6E-39 T 29-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMALA_RS07310 3a03e0d5a41be39a7eed77170fc0627a 1168 Gene3D G3DSA:3.10.196.10 950 1057 3.6E-30 T 29-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMALA_RS07310 3a03e0d5a41be39a7eed77170fc0627a 1168 SMART SM01018 646 728 1.4E-42 T 29-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMALA_RS07310 3a03e0d5a41be39a7eed77170fc0627a 1168 SUPERFAMILY SSF56507 893 1167 1.83E-95 T 29-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMALA_RS07310 3a03e0d5a41be39a7eed77170fc0627a 1168 TIGRFAM TIGR02082 metH: methionine synthase 22 1166 0.0 T 29-03-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMALA_RS07310 3a03e0d5a41be39a7eed77170fc0627a 1168 Pfam PF02574 Homocysteine S-methyltransferase 26 315 1.9E-61 T 29-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 SMALA_RS07310 3a03e0d5a41be39a7eed77170fc0627a 1168 Gene3D G3DSA:3.20.20.330 11 328 7.8E-88 T 29-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 SMALA_RS07310 3a03e0d5a41be39a7eed77170fc0627a 1168 Pfam PF02965 Vitamin B12 dependent methionine synthase, activation domain 966 1166 1.3E-41 T 29-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMALA_RS07310 3a03e0d5a41be39a7eed77170fc0627a 1168 SUPERFAMILY SSF82282 17 390 5.89E-104 T 29-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 SMALA_RS07310 3a03e0d5a41be39a7eed77170fc0627a 1168 Gene3D G3DSA:3.40.50.280 722 891 1.4E-45 T 29-03-2018 SMALA_RS07310 3a03e0d5a41be39a7eed77170fc0627a 1168 SUPERFAMILY SSF52242 728 863 2.22E-38 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 SMALA_RS07310 3a03e0d5a41be39a7eed77170fc0627a 1168 SUPERFAMILY SSF51717 348 619 4.45E-75 T 29-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMALA_RS07310 3a03e0d5a41be39a7eed77170fc0627a 1168 Gene3D G3DSA:1.10.1240.10 634 721 7.7E-33 T 29-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMALA_RS07310 3a03e0d5a41be39a7eed77170fc0627a 1168 SUPERFAMILY SSF47644 644 727 6.41E-25 T 29-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMALA_RS07310 3a03e0d5a41be39a7eed77170fc0627a 1168 Pfam PF02607 B12 binding domain 649 721 6.9E-26 T 29-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMALA_RS07310 3a03e0d5a41be39a7eed77170fc0627a 1168 Pfam PF00809 Pterin binding enzyme 351 587 1.7E-45 T 29-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMALA_RS09660 509170df86e66fad3125188b1d4b0b72 712 SUPERFAMILY SSF52540 42 91 3.11E-34 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS09660 509170df86e66fad3125188b1d4b0b72 712 SUPERFAMILY SSF52540 466 586 3.11E-34 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS09660 509170df86e66fad3125188b1d4b0b72 712 Gene3D G3DSA:3.40.50.300 422 596 2.1E-31 T 29-03-2018 SMALA_RS09660 509170df86e66fad3125188b1d4b0b72 712 Gene3D G3DSA:3.40.50.300 20 412 1.6E-31 T 29-03-2018 SMALA_RS09660 509170df86e66fad3125188b1d4b0b72 712 SUPERFAMILY SSF46600 662 705 1.28E-8 T 29-03-2018 IPR001943 UVR domain GO:0005515 SMALA_RS09660 509170df86e66fad3125188b1d4b0b72 712 Pfam PF02151 UvrB/uvrC motif 668 702 9.2E-6 T 29-03-2018 IPR001943 UVR domain GO:0005515 SMALA_RS09660 509170df86e66fad3125188b1d4b0b72 712 Pfam PF00271 Helicase conserved C-terminal domain 441 551 2.0E-17 T 29-03-2018 IPR001650 Helicase, C-terminal SMALA_RS09660 509170df86e66fad3125188b1d4b0b72 712 SMART SM00490 467 553 2.7E-18 T 29-03-2018 IPR001650 Helicase, C-terminal SMALA_RS09660 509170df86e66fad3125188b1d4b0b72 712 SMART SM00487 18 433 2.8E-25 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain SMALA_RS09660 509170df86e66fad3125188b1d4b0b72 712 Gene3D G3DSA:4.10.860.10 641 707 2.3E-10 T 29-03-2018 IPR001943 UVR domain GO:0005515 SMALA_RS09660 509170df86e66fad3125188b1d4b0b72 712 Pfam PF12344 Ultra-violet resistance protein B 559 600 1.6E-19 T 29-03-2018 IPR024759 UvrB, YAD/RRR-motif-containing domain SMALA_RS09660 509170df86e66fad3125188b1d4b0b72 712 Pfam PF04851 Type III restriction enzyme, res subunit 25 134 5.3E-8 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 SMALA_RS09660 509170df86e66fad3125188b1d4b0b72 712 Hamap MF_00204 UvrABC system protein B [uvrB]. 12 702 42.375 T 29-03-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 SMALA_RS09660 509170df86e66fad3125188b1d4b0b72 712 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 14 700 0.0 T 29-03-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 SMALA_RS09660 509170df86e66fad3125188b1d4b0b72 712 SUPERFAMILY SSF52540 13 422 5.63E-134 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS40570 dffdfb47841889ec0bb46129e0442cb4 290 SUPERFAMILY SSF52540 22 268 7.66E-77 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS40570 dffdfb47841889ec0bb46129e0442cb4 290 Pfam PF00005 ABC transporter 48 196 1.0E-34 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS40570 dffdfb47841889ec0bb46129e0442cb4 290 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 248 279 1.6E-7 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMALA_RS40570 dffdfb47841889ec0bb46129e0442cb4 290 Gene3D G3DSA:3.40.50.300 19 282 5.4E-79 T 29-03-2018 SMALA_RS40570 dffdfb47841889ec0bb46129e0442cb4 290 ProSitePatterns PS00211 ABC transporters family signature. 169 183 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS40570 dffdfb47841889ec0bb46129e0442cb4 290 SMART SM00382 57 254 7.6E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS09065 45836b4b9224279fe1f7af545bb1e467 328 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 245 316 7.1E-5 T 29-03-2018 IPR001357 BRCT domain SMALA_RS09065 45836b4b9224279fe1f7af545bb1e467 328 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 26 186 1.5E-25 T 29-03-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMALA_RS09065 45836b4b9224279fe1f7af545bb1e467 328 SUPERFAMILY SSF52113 239 317 7.85E-12 T 29-03-2018 IPR001357 BRCT domain SMALA_RS09065 45836b4b9224279fe1f7af545bb1e467 328 Gene3D G3DSA:3.40.50.10190 203 318 2.7E-11 T 29-03-2018 IPR001357 BRCT domain SMALA_RS09065 45836b4b9224279fe1f7af545bb1e467 328 SUPERFAMILY SSF53098 23 191 1.06E-41 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SMALA_RS09065 45836b4b9224279fe1f7af545bb1e467 328 Gene3D G3DSA:3.30.420.10 24 190 5.0E-31 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SMALA_RS09065 45836b4b9224279fe1f7af545bb1e467 328 SMART SM00479 25 189 1.5E-32 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III SMALA_RS09065 45836b4b9224279fe1f7af545bb1e467 328 Pfam PF00929 Exonuclease 28 180 1.3E-19 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III SMALA_RS04625 93bde7343a0f809a9d9b3b76e069d84e 470 Pfam PF00394 Multicopper oxidase 202 290 2.3E-11 T 29-03-2018 IPR001117 Multicopper oxidase, type 1 GO:0055114 SMALA_RS04625 93bde7343a0f809a9d9b3b76e069d84e 470 SUPERFAMILY SSF49503 189 298 7.17E-16 T 29-03-2018 IPR008972 Cupredoxin SMALA_RS04625 93bde7343a0f809a9d9b3b76e069d84e 470 Gene3D G3DSA:2.60.40.420 39 175 2.6E-25 T 29-03-2018 IPR008972 Cupredoxin SMALA_RS04625 93bde7343a0f809a9d9b3b76e069d84e 470 Pfam PF07731 Multicopper oxidase 360 467 3.9E-20 T 29-03-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 SMALA_RS04625 93bde7343a0f809a9d9b3b76e069d84e 470 Gene3D G3DSA:2.60.40.420 345 469 8.3E-30 T 29-03-2018 IPR008972 Cupredoxin SMALA_RS04625 93bde7343a0f809a9d9b3b76e069d84e 470 Gene3D G3DSA:2.60.40.420 185 344 7.8E-21 T 29-03-2018 IPR008972 Cupredoxin SMALA_RS04625 93bde7343a0f809a9d9b3b76e069d84e 470 SUPERFAMILY SSF49503 341 468 3.76E-28 T 29-03-2018 IPR008972 Cupredoxin SMALA_RS04625 93bde7343a0f809a9d9b3b76e069d84e 470 ProSitePatterns PS00080 Multicopper oxidases signature 2. 451 462 - T 29-03-2018 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 SMALA_RS04625 93bde7343a0f809a9d9b3b76e069d84e 470 SUPERFAMILY SSF49503 46 176 5.42E-27 T 29-03-2018 IPR008972 Cupredoxin SMALA_RS04625 93bde7343a0f809a9d9b3b76e069d84e 470 Pfam PF07732 Multicopper oxidase 61 176 3.5E-21 T 29-03-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 SMALA_RS02150 2959ef4816b9b73fa8632b373e502a21 157 Gene3D G3DSA:2.30.110.10 5 157 1.8E-15 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS02150 2959ef4816b9b73fa8632b373e502a21 157 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 25 100 5.9E-5 T 29-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 SMALA_RS02150 2959ef4816b9b73fa8632b373e502a21 157 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 25 156 1.5E-24 T 29-03-2018 IPR019920 F420-binding domain, putative SMALA_RS02150 2959ef4816b9b73fa8632b373e502a21 157 SUPERFAMILY SSF50475 25 156 3.93E-16 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS10785 53bb1abe5d942eb173b93a4da5e4b1a0 210 Gene3D G3DSA:1.10.10.10 1 64 1.8E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS10785 53bb1abe5d942eb173b93a4da5e4b1a0 210 SUPERFAMILY SSF46785 6 93 1.3E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS10785 53bb1abe5d942eb173b93a4da5e4b1a0 210 Pfam PF00392 Bacterial regulatory proteins, gntR family 8 68 1.6E-12 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS10785 53bb1abe5d942eb173b93a4da5e4b1a0 210 SMART SM00895 78 202 2.4E-18 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS10785 53bb1abe5d942eb173b93a4da5e4b1a0 210 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 58 1.1E-5 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS10785 53bb1abe5d942eb173b93a4da5e4b1a0 210 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 28 42 1.1E-5 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS10785 53bb1abe5d942eb173b93a4da5e4b1a0 210 SMART SM00345 10 68 1.7E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS10785 53bb1abe5d942eb173b93a4da5e4b1a0 210 Gene3D G3DSA:1.20.120.530 65 210 4.9E-31 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS10785 53bb1abe5d942eb173b93a4da5e4b1a0 210 Pfam PF07729 FCD domain 78 201 6.2E-24 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS10785 53bb1abe5d942eb173b93a4da5e4b1a0 210 SUPERFAMILY SSF48008 75 208 7.59E-26 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS23700 ae2befd1e4c7d487d20d9a0e25e2b304 380 Gene3D G3DSA:3.60.70.12 10 380 9.3E-128 T 29-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 SMALA_RS23700 ae2befd1e4c7d487d20d9a0e25e2b304 380 SUPERFAMILY SSF56266 8 224 7.32E-73 T 29-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 SMALA_RS23700 ae2befd1e4c7d487d20d9a0e25e2b304 380 SUPERFAMILY SSF56266 255 367 7.32E-73 T 29-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 SMALA_RS23700 ae2befd1e4c7d487d20d9a0e25e2b304 380 Pfam PF03576 Peptidase family S58 18 368 1.1E-72 T 29-03-2018 IPR005321 Peptidase S58, DmpA SMALA_RS23990 84710adb30cda452d55e04e3dc6f320f 347 PIRSF PIRSF000808 35 347 3.0E-106 T 29-03-2018 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0008108|GO:0008270|GO:0033499 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-70370 SMALA_RS23990 84710adb30cda452d55e04e3dc6f320f 347 Pfam PF02744 Galactose-1-phosphate uridyl transferase, C-terminal domain 195 342 1.4E-13 T 29-03-2018 IPR005850 Galactose-1-phosphate uridyl transferase, C-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-70370 SMALA_RS23990 84710adb30cda452d55e04e3dc6f320f 347 Pfam PF01087 Galactose-1-phosphate uridyl transferase, N-terminal domain 103 178 4.3E-26 T 29-03-2018 IPR005849 Galactose-1-phosphate uridyl transferase, N-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-70370 SMALA_RS23990 84710adb30cda452d55e04e3dc6f320f 347 Gene3D G3DSA:3.30.428.10 38 76 2.6E-4 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 SMALA_RS23990 84710adb30cda452d55e04e3dc6f320f 347 SUPERFAMILY SSF54197 38 179 8.0E-47 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 SMALA_RS23990 84710adb30cda452d55e04e3dc6f320f 347 TIGRFAM TIGR00209 galT_1: galactose-1-phosphate uridylyltransferase 103 345 2.2E-39 T 29-03-2018 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0008108|GO:0008270|GO:0033499 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-70370 SMALA_RS23990 84710adb30cda452d55e04e3dc6f320f 347 ProSitePatterns PS00117 Galactose-1-phosphate uridyl transferase family 1 active site signature. 154 171 - T 29-03-2018 IPR019779 Galactose-1-phosphate uridyl transferase, class I His-active site KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-70370 SMALA_RS23990 84710adb30cda452d55e04e3dc6f320f 347 SUPERFAMILY SSF54197 182 345 3.23E-36 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 SMALA_RS23990 84710adb30cda452d55e04e3dc6f320f 347 Gene3D G3DSA:3.30.428.10 169 347 1.3E-27 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 SMALA_RS23990 84710adb30cda452d55e04e3dc6f320f 347 Gene3D G3DSA:3.30.428.10 77 168 1.2E-35 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 SMALA_RS06650 8ddad38d993eb4a47ec7a7424f1fe597 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 6.7E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS06650 8ddad38d993eb4a47ec7a7424f1fe597 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 6.7E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS06650 8ddad38d993eb4a47ec7a7424f1fe597 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 6.7E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS06650 8ddad38d993eb4a47ec7a7424f1fe597 238 Gene3D G3DSA:3.40.50.720 2 238 1.9E-36 T 29-03-2018 SMALA_RS06650 8ddad38d993eb4a47ec7a7424f1fe597 238 Pfam PF00106 short chain dehydrogenase 12 197 1.4E-21 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS06650 8ddad38d993eb4a47ec7a7424f1fe597 238 SUPERFAMILY SSF51735 11 238 2.15E-51 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS04870 67ab8e05d7994c10945dd2ce44b85f8f 300 SUPERFAMILY SSF54637 131 299 1.23E-37 T 29-03-2018 IPR029069 HotDog domain SMALA_RS04870 67ab8e05d7994c10945dd2ce44b85f8f 300 Pfam PF13622 Thioesterase-like superfamily 37 297 3.9E-50 T 29-03-2018 SMALA_RS04870 67ab8e05d7994c10945dd2ce44b85f8f 300 SUPERFAMILY SSF54637 11 121 1.87E-30 T 29-03-2018 IPR029069 HotDog domain SMALA_RS04870 67ab8e05d7994c10945dd2ce44b85f8f 300 Gene3D G3DSA:3.10.129.10 1 119 9.2E-33 T 29-03-2018 SMALA_RS04870 67ab8e05d7994c10945dd2ce44b85f8f 300 Gene3D G3DSA:3.10.129.10 140 300 3.8E-43 T 29-03-2018 SMALA_RS22120 55f5c082b649cb88c4e42372bf06c1ae 444 TIGRFAM TIGR01962 NuoD: NADH dehydrogenase (quinone), D subunit 42 444 5.0E-174 T 29-03-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS22120 55f5c082b649cb88c4e42372bf06c1ae 444 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 79 90 - T 29-03-2018 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS22120 55f5c082b649cb88c4e42372bf06c1ae 444 Gene3D G3DSA:1.10.645.10 232 440 2.7E-44 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS22120 55f5c082b649cb88c4e42372bf06c1ae 444 SUPERFAMILY SSF56762 52 444 2.49E-122 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS22120 55f5c082b649cb88c4e42372bf06c1ae 444 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 38 444 47.186 T 29-03-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS22120 55f5c082b649cb88c4e42372bf06c1ae 444 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 159 444 7.8E-114 T 29-03-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS22120 55f5c082b649cb88c4e42372bf06c1ae 444 Gene3D G3DSA:1.10.645.10 38 231 1.1E-48 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS25620 049656206fd5ac5313e7060893338dde 345 Gene3D G3DSA:3.40.50.300 7 345 9.8E-84 T 29-03-2018 SMALA_RS25620 049656206fd5ac5313e7060893338dde 345 SMART SM00382 47 240 3.3E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS25620 049656206fd5ac5313e7060893338dde 345 SUPERFAMILY SSF52540 10 262 6.39E-76 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS25620 049656206fd5ac5313e7060893338dde 345 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 243 311 9.7E-15 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMALA_RS25620 049656206fd5ac5313e7060893338dde 345 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS25620 049656206fd5ac5313e7060893338dde 345 Pfam PF00005 ABC transporter 39 190 5.7E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS25620 049656206fd5ac5313e7060893338dde 345 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 241 335 1.2E-21 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMALA_RS10360 3f36fd4313582097faf270ca551af3be 644 Pfam PF03793 PASTA domain 513 576 2.9E-15 T 29-03-2018 IPR005543 PASTA domain SMALA_RS10360 3f36fd4313582097faf270ca551af3be 644 Pfam PF03793 PASTA domain 380 440 1.4E-13 T 29-03-2018 IPR005543 PASTA domain SMALA_RS10360 3f36fd4313582097faf270ca551af3be 644 Pfam PF03793 PASTA domain 581 639 2.0E-12 T 29-03-2018 IPR005543 PASTA domain SMALA_RS10360 3f36fd4313582097faf270ca551af3be 644 Pfam PF03793 PASTA domain 447 509 7.0E-13 T 29-03-2018 IPR005543 PASTA domain SMALA_RS10360 3f36fd4313582097faf270ca551af3be 644 Gene3D G3DSA:1.10.510.10 86 554 4.0E-52 T 29-03-2018 SMALA_RS10360 3f36fd4313582097faf270ca551af3be 644 Gene3D G3DSA:3.30.200.20 16 85 8.4E-18 T 29-03-2018 SMALA_RS10360 3f36fd4313582097faf270ca551af3be 644 SMART SM00220 18 271 2.3E-51 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMALA_RS10360 3f36fd4313582097faf270ca551af3be 644 SMART SM00740 577 641 2.2E-11 T 29-03-2018 IPR005543 PASTA domain SMALA_RS10360 3f36fd4313582097faf270ca551af3be 644 SMART SM00740 442 509 9.3E-13 T 29-03-2018 IPR005543 PASTA domain SMALA_RS10360 3f36fd4313582097faf270ca551af3be 644 SMART SM00740 510 576 4.8E-15 T 29-03-2018 IPR005543 PASTA domain SMALA_RS10360 3f36fd4313582097faf270ca551af3be 644 SMART SM00740 375 441 6.5E-10 T 29-03-2018 IPR005543 PASTA domain SMALA_RS10360 3f36fd4313582097faf270ca551af3be 644 SUPERFAMILY SSF56112 15 269 1.2E-71 T 29-03-2018 IPR011009 Protein kinase-like domain SMALA_RS10360 3f36fd4313582097faf270ca551af3be 644 Pfam PF00069 Protein kinase domain 18 250 9.3E-48 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMALA_RS10360 3f36fd4313582097faf270ca551af3be 644 SUPERFAMILY SSF54184 581 640 1.16E-7 T 29-03-2018 SMALA_RS10360 3f36fd4313582097faf270ca551af3be 644 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 137 149 - T 29-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMALA_RS37425 33c5fcd07f4c8bec65084199f29b8e24 293 Gene3D G3DSA:3.40.50.300 7 261 3.0E-100 T 29-03-2018 SMALA_RS37425 33c5fcd07f4c8bec65084199f29b8e24 293 SUPERFAMILY SSF52540 46 234 4.78E-30 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS37425 33c5fcd07f4c8bec65084199f29b8e24 293 TIGRFAM TIGR03707 PPK2_P_aer: polyphosphate kinase 2 17 239 9.0E-116 T 29-03-2018 IPR022486 Polyphosphate kinase 2, PA0141 GO:0006793|GO:0008976 SMALA_RS37425 33c5fcd07f4c8bec65084199f29b8e24 293 PIRSF PIRSF028756 2 270 2.4E-125 T 29-03-2018 IPR016898 Polyphosphate kinase 2 SMALA_RS37425 33c5fcd07f4c8bec65084199f29b8e24 293 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 17 239 1.0E-107 T 29-03-2018 IPR022488 Polyphosphate kinase-2-related SMALA_RS34915 71faf6c5c395df4941b29220bb03a610 288 Gene3D G3DSA:1.10.3100.10 13 166 3.8E-15 T 29-03-2018 IPR027910 YdiL-like domain SMALA_RS34915 71faf6c5c395df4941b29220bb03a610 288 Pfam PF13560 Helix-turn-helix domain 18 76 5.8E-10 T 29-03-2018 SMALA_RS34915 71faf6c5c395df4941b29220bb03a610 288 SUPERFAMILY SSF47413 13 72 3.38E-8 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS34915 71faf6c5c395df4941b29220bb03a610 288 SMART SM00530 21 76 3.6E-6 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS32385 6731070323c3e9ea045355168658918a 285 SUPERFAMILY SSF48179 189 285 1.87E-29 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMALA_RS32385 6731070323c3e9ea045355168658918a 285 SUPERFAMILY SSF51735 4 186 9.86E-48 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS32385 6731070323c3e9ea045355168658918a 285 PIRSF PIRSF000105 2 285 6.4E-79 T 29-03-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 SMALA_RS32385 6731070323c3e9ea045355168658918a 285 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 189 285 9.3E-33 T 29-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 SMALA_RS32385 6731070323c3e9ea045355168658918a 285 Gene3D G3DSA:3.40.50.720 1 187 1.2E-48 T 29-03-2018 SMALA_RS32385 6731070323c3e9ea045355168658918a 285 Gene3D G3DSA:1.10.1040.10 188 285 8.0E-32 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMALA_RS32385 6731070323c3e9ea045355168658918a 285 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 7 186 2.2E-59 T 29-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 SMALA_RS26840 68bdc64e6336d307d2039f18454ff569 710 TIGRFAM TIGR00767 rho: transcription termination factor Rho 51 699 9.9E-200 T 29-03-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 SMALA_RS26840 68bdc64e6336d307d2039f18454ff569 710 Gene3D G3DSA:3.40.50.300 407 651 9.5E-51 T 29-03-2018 SMALA_RS26840 68bdc64e6336d307d2039f18454ff569 710 Gene3D G3DSA:2.40.50.140 48 406 4.5E-44 T 29-03-2018 SMALA_RS26840 68bdc64e6336d307d2039f18454ff569 710 Pfam PF07497 Rho termination factor, RNA-binding domain 336 410 8.3E-30 T 29-03-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 SMALA_RS26840 68bdc64e6336d307d2039f18454ff569 710 SMART SM00959 50 92 2.6E-11 T 29-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 SMALA_RS26840 68bdc64e6336d307d2039f18454ff569 710 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 441 645 2.0E-20 T 29-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SMALA_RS26840 68bdc64e6336d307d2039f18454ff569 710 SUPERFAMILY SSF68912 50 91 2.86E-5 T 29-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 SMALA_RS26840 68bdc64e6336d307d2039f18454ff569 710 Pfam PF07498 Rho termination factor, N-terminal domain 51 89 3.2E-11 T 29-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 SMALA_RS26840 68bdc64e6336d307d2039f18454ff569 710 SUPERFAMILY SSF52540 374 652 5.27E-66 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS26840 68bdc64e6336d307d2039f18454ff569 710 SUPERFAMILY SSF50249 336 410 1.68E-17 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMALA_RS26840 68bdc64e6336d307d2039f18454ff569 710 Hamap MF_01884 Transcription termination factor Rho [rho]. 328 701 204.401 T 29-03-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 SMALA_RS26840 68bdc64e6336d307d2039f18454ff569 710 SMART SM00357 337 403 1.5E-11 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 SMALA_RS26840 68bdc64e6336d307d2039f18454ff569 710 SMART SM00382 452 637 8.1E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS15535 8312af0cdd72dc35dbc762cd0c2f8e10 368 SMART SM00937 84 194 4.8E-44 T 29-03-2018 IPR005139 Peptide chain release factor GO:0006415 SMALA_RS15535 8312af0cdd72dc35dbc762cd0c2f8e10 368 SUPERFAMILY SSF75620 30 366 7.98E-122 T 29-03-2018 SMALA_RS15535 8312af0cdd72dc35dbc762cd0c2f8e10 368 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 244 260 - T 29-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 SMALA_RS15535 8312af0cdd72dc35dbc762cd0c2f8e10 368 Pfam PF00472 RF-1 domain 229 336 4.9E-38 T 29-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 SMALA_RS15535 8312af0cdd72dc35dbc762cd0c2f8e10 368 TIGRFAM TIGR00020 prfB: peptide chain release factor 2 3 363 2.9E-155 T 29-03-2018 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 SMALA_RS15535 8312af0cdd72dc35dbc762cd0c2f8e10 368 Hamap MF_00094 Peptide chain release factor 2 [prfB]. 2 364 38.264 T 29-03-2018 IPR020853 Peptide chain release factor 2, bacterial GO:0005737|GO:0006415|GO:0016149 SMALA_RS15535 8312af0cdd72dc35dbc762cd0c2f8e10 368 Pfam PF03462 PCRF domain 30 219 2.2E-55 T 29-03-2018 IPR005139 Peptide chain release factor GO:0006415 SMALA_RS15535 8312af0cdd72dc35dbc762cd0c2f8e10 368 Gene3D G3DSA:1.20.58.410 2 115 4.6E-29 T 29-03-2018 SMALA_RS15535 8312af0cdd72dc35dbc762cd0c2f8e10 368 Gene3D G3DSA:3.30.160.20 225 307 1.0E-32 T 29-03-2018 SMALA_RS15290 f2ad309b6d922a8c28fb6490370de159 1336 SMART SM00824 Thioesterase 1077 1333 0.0059 T 29-03-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 SMALA_RS15290 f2ad309b6d922a8c28fb6490370de159 1336 Pfam PF13193 AMP-binding enzyme C-terminal domain 882 957 9.0E-11 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS15290 f2ad309b6d922a8c28fb6490370de159 1336 Pfam PF00668 Condensation domain 10 449 4.2E-57 T 29-03-2018 IPR001242 Condensation domain SMALA_RS15290 f2ad309b6d922a8c28fb6490370de159 1336 Gene3D G3DSA:3.30.300.30 869 985 1.6E-36 T 29-03-2018 SMALA_RS15290 f2ad309b6d922a8c28fb6490370de159 1336 Gene3D G3DSA:3.40.50.980 622 778 2.4E-47 T 29-03-2018 SMALA_RS15290 f2ad309b6d922a8c28fb6490370de159 1336 Gene3D G3DSA:3.30.559.10 1 197 6.1E-22 T 29-03-2018 SMALA_RS15290 f2ad309b6d922a8c28fb6490370de159 1336 SUPERFAMILY SSF52777 196 433 1.89E-38 T 29-03-2018 SMALA_RS15290 f2ad309b6d922a8c28fb6490370de159 1336 SUPERFAMILY SSF47336 975 1047 6.67E-18 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS15290 f2ad309b6d922a8c28fb6490370de159 1336 ProSitePatterns PS00455 Putative AMP-binding domain signature. 616 627 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS15290 f2ad309b6d922a8c28fb6490370de159 1336 SUPERFAMILY SSF56801 433 995 1.44E-167 T 29-03-2018 SMALA_RS15290 f2ad309b6d922a8c28fb6490370de159 1336 Gene3D G3DSA:3.40.50.1820 1060 1332 3.3E-32 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS15290 f2ad309b6d922a8c28fb6490370de159 1336 Gene3D G3DSA:1.10.1200.10 986 1059 3.7E-22 T 29-03-2018 SMALA_RS15290 f2ad309b6d922a8c28fb6490370de159 1336 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 492 897 3.0E-139 T 29-03-2018 IPR010071 Amino acid adenylation domain SMALA_RS15290 f2ad309b6d922a8c28fb6490370de159 1336 Gene3D G3DSA:2.30.38.10 783 864 4.8E-27 T 29-03-2018 SMALA_RS15290 f2ad309b6d922a8c28fb6490370de159 1336 SMART SM00823 Phosphopantetheine attachment site 982 1051 0.0026 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS15290 f2ad309b6d922a8c28fb6490370de159 1336 SUPERFAMILY SSF52777 12 190 6.23E-26 T 29-03-2018 SMALA_RS15290 f2ad309b6d922a8c28fb6490370de159 1336 Pfam PF00501 AMP-binding enzyme 472 874 8.8E-107 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS15290 f2ad309b6d922a8c28fb6490370de159 1336 SUPERFAMILY SSF53474 1059 1331 6.54E-58 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS15290 f2ad309b6d922a8c28fb6490370de159 1336 Gene3D G3DSA:3.40.50.980 462 621 1.6E-47 T 29-03-2018 SMALA_RS15290 f2ad309b6d922a8c28fb6490370de159 1336 Pfam PF00975 Thioesterase domain 1075 1316 1.5E-30 T 29-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 SMALA_RS15290 f2ad309b6d922a8c28fb6490370de159 1336 Pfam PF00550 Phosphopantetheine attachment site 984 1047 2.1E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS43110 94b42a733bacbaaa42be8ec647bbd20a 149 ProSitePatterns PS00893 Nudix box signature. 45 66 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 SMALA_RS43110 94b42a733bacbaaa42be8ec647bbd20a 149 SUPERFAMILY SSF55811 10 145 1.11E-30 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMALA_RS43110 94b42a733bacbaaa42be8ec647bbd20a 149 Gene3D G3DSA:3.90.79.10 8 149 8.7E-38 T 29-03-2018 SMALA_RS43110 94b42a733bacbaaa42be8ec647bbd20a 149 Pfam PF00293 NUDIX domain 12 128 1.6E-20 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SMALA_RS43110 94b42a733bacbaaa42be8ec647bbd20a 149 PRINTS PR00502 NUDIX hydrolase family signature 54 69 3.7E-5 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMALA_RS43110 94b42a733bacbaaa42be8ec647bbd20a 149 PRINTS PR00502 NUDIX hydrolase family signature 40 54 3.7E-5 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMALA_RS36695 7dd8ab6c86a58d80d37b766a556c3239 2398 SUPERFAMILY SSF47336 2267 2353 9.55E-22 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS36695 7dd8ab6c86a58d80d37b766a556c3239 2398 Pfam PF00698 Acyl transferase domain 1560 1883 4.7E-86 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS36695 7dd8ab6c86a58d80d37b766a556c3239 2398 Pfam PF00698 Acyl transferase domain 524 851 7.0E-58 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS36695 7dd8ab6c86a58d80d37b766a556c3239 2398 Gene3D G3DSA:3.40.366.10 707 823 7.4E-33 T 29-03-2018 SMALA_RS36695 7dd8ab6c86a58d80d37b766a556c3239 2398 Gene3D G3DSA:3.40.366.10 1742 1864 3.0E-25 T 29-03-2018 SMALA_RS36695 7dd8ab6c86a58d80d37b766a556c3239 2398 Gene3D G3DSA:3.40.47.10 1 256 1.5E-78 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS36695 7dd8ab6c86a58d80d37b766a556c3239 2398 Pfam PF14765 Polyketide synthase dehydratase 1933 2222 9.0E-49 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS36695 7dd8ab6c86a58d80d37b766a556c3239 2398 SUPERFAMILY SSF55048 1684 1752 2.09E-10 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS36695 7dd8ab6c86a58d80d37b766a556c3239 2398 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1180 1196 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS36695 7dd8ab6c86a58d80d37b766a556c3239 2398 Gene3D G3DSA:3.40.47.10 259 420 3.9E-58 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS36695 7dd8ab6c86a58d80d37b766a556c3239 2398 Gene3D G3DSA:3.40.47.10 1282 1443 1.4E-63 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS36695 7dd8ab6c86a58d80d37b766a556c3239 2398 SUPERFAMILY SSF52151 1559 1686 1.86E-63 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS36695 7dd8ab6c86a58d80d37b766a556c3239 2398 SUPERFAMILY SSF52151 1753 1852 1.86E-63 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS36695 7dd8ab6c86a58d80d37b766a556c3239 2398 Gene3D G3DSA:1.10.1200.10 918 1017 1.0E-19 T 29-03-2018 SMALA_RS36695 7dd8ab6c86a58d80d37b766a556c3239 2398 Gene3D G3DSA:1.10.1200.10 2267 2384 9.5E-23 T 29-03-2018 SMALA_RS36695 7dd8ab6c86a58d80d37b766a556c3239 2398 SUPERFAMILY SSF53901 1 368 1.09E-85 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS36695 7dd8ab6c86a58d80d37b766a556c3239 2398 Gene3D G3DSA:3.30.70.250 1695 1741 9.7E-14 T 29-03-2018 SMALA_RS36695 7dd8ab6c86a58d80d37b766a556c3239 2398 Pfam PF00550 Phosphopantetheine attachment site 2275 2340 4.9E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS36695 7dd8ab6c86a58d80d37b766a556c3239 2398 Pfam PF00550 Phosphopantetheine attachment site 923 990 5.2E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS36695 7dd8ab6c86a58d80d37b766a556c3239 2398 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 372 487 4.9E-20 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS36695 7dd8ab6c86a58d80d37b766a556c3239 2398 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1395 1490 5.4E-15 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS36695 7dd8ab6c86a58d80d37b766a556c3239 2398 SUPERFAMILY SSF52151 522 653 6.54E-71 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS36695 7dd8ab6c86a58d80d37b766a556c3239 2398 SUPERFAMILY SSF52151 717 812 6.54E-71 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS36695 7dd8ab6c86a58d80d37b766a556c3239 2398 SUPERFAMILY SSF53901 1013 1389 9.84E-102 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS36695 7dd8ab6c86a58d80d37b766a556c3239 2398 Gene3D G3DSA:3.10.129.10 1934 2067 7.7E-4 T 29-03-2018 SMALA_RS36695 7dd8ab6c86a58d80d37b766a556c3239 2398 Gene3D G3DSA:3.40.366.10 1554 1694 1.0E-43 T 29-03-2018 SMALA_RS36695 7dd8ab6c86a58d80d37b766a556c3239 2398 SMART SM00825 Beta-ketoacyl synthase 1 422 2.2E-194 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS36695 7dd8ab6c86a58d80d37b766a556c3239 2398 SMART SM00825 Beta-ketoacyl synthase 1019 1445 8.8E-228 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS36695 7dd8ab6c86a58d80d37b766a556c3239 2398 ProSitePatterns PS00012 Phosphopantetheine attachment site. 949 964 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS36695 7dd8ab6c86a58d80d37b766a556c3239 2398 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 252 369 1.8E-38 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS36695 7dd8ab6c86a58d80d37b766a556c3239 2398 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1275 1392 1.0E-45 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS36695 7dd8ab6c86a58d80d37b766a556c3239 2398 Gene3D G3DSA:3.40.47.10 1018 1279 2.8E-86 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS36695 7dd8ab6c86a58d80d37b766a556c3239 2398 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1 244 1.8E-80 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS36695 7dd8ab6c86a58d80d37b766a556c3239 2398 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1017 1267 6.9E-89 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS36695 7dd8ab6c86a58d80d37b766a556c3239 2398 Gene3D G3DSA:3.40.366.10 521 661 5.2E-42 T 29-03-2018 SMALA_RS36695 7dd8ab6c86a58d80d37b766a556c3239 2398 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1561 1864 3.4E-111 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS36695 7dd8ab6c86a58d80d37b766a556c3239 2398 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 525 832 9.5E-122 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS36695 7dd8ab6c86a58d80d37b766a556c3239 2398 Gene3D G3DSA:3.30.70.250 662 706 1.1E-20 T 29-03-2018 SMALA_RS36695 7dd8ab6c86a58d80d37b766a556c3239 2398 SUPERFAMILY SSF55048 652 715 2.22E-14 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS36695 7dd8ab6c86a58d80d37b766a556c3239 2398 SMART SM00823 Phosphopantetheine attachment site 2272 2344 3.6E-30 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS36695 7dd8ab6c86a58d80d37b766a556c3239 2398 SMART SM00823 Phosphopantetheine attachment site 922 994 2.3E-26 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS36695 7dd8ab6c86a58d80d37b766a556c3239 2398 SUPERFAMILY SSF47336 921 1032 1.06E-21 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS36695 7dd8ab6c86a58d80d37b766a556c3239 2398 SMART SM00826 1933 2101 3.8E-71 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS36695 7dd8ab6c86a58d80d37b766a556c3239 2398 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2299 2314 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS36695 7dd8ab6c86a58d80d37b766a556c3239 2398 SMART SM01294 923 990 1.5E-4 T 29-03-2018 SMALA_RS36695 7dd8ab6c86a58d80d37b766a556c3239 2398 SMART SM01294 2273 2340 6.5E-5 T 29-03-2018 SMALA_RS37975 7d6bda797f3bcfb711a2f42047c36c68 258 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMALA_RS37975 7d6bda797f3bcfb711a2f42047c36c68 258 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 250 1.8E-49 T 29-03-2018 SMALA_RS37975 7d6bda797f3bcfb711a2f42047c36c68 258 SUPERFAMILY SSF51735 5 250 5.47E-64 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS37975 7d6bda797f3bcfb711a2f42047c36c68 258 Gene3D G3DSA:3.40.50.720 3 253 2.8E-58 T 29-03-2018 SMALA_RS37975 7d6bda797f3bcfb711a2f42047c36c68 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 4.1E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS37975 7d6bda797f3bcfb711a2f42047c36c68 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 4.1E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS37975 7d6bda797f3bcfb711a2f42047c36c68 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 4.1E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS37975 7d6bda797f3bcfb711a2f42047c36c68 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 2.4E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS37975 7d6bda797f3bcfb711a2f42047c36c68 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 2.4E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS37975 7d6bda797f3bcfb711a2f42047c36c68 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 2.4E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS37975 7d6bda797f3bcfb711a2f42047c36c68 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 2.4E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS37975 7d6bda797f3bcfb711a2f42047c36c68 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.4E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS37975 7d6bda797f3bcfb711a2f42047c36c68 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 2.4E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS39770 50efe205a2d9d414af5bae398f0c0f1a 160 Gene3D G3DSA:3.40.50.450 1 159 3.4E-16 T 29-03-2018 SMALA_RS37120 3d301b45bb4a94dbee2cca2198c0798c 936 Gene3D G3DSA:2.60.40.10 640 714 1.3E-10 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS37120 3d301b45bb4a94dbee2cca2198c0798c 936 SUPERFAMILY SSF53300 88 287 1.75E-18 T 29-03-2018 IPR002035 von Willebrand factor, type A SMALA_RS37120 3d301b45bb4a94dbee2cca2198c0798c 936 Pfam PF02494 HYR domain 637 713 6.7E-7 T 29-03-2018 IPR003410 HYR domain SMALA_RS37120 3d301b45bb4a94dbee2cca2198c0798c 936 Pfam PF00092 von Willebrand factor type A domain 88 246 1.4E-9 T 29-03-2018 IPR002035 von Willebrand factor, type A SMALA_RS37120 3d301b45bb4a94dbee2cca2198c0798c 936 Gene3D G3DSA:2.60.40.10 715 844 1.0E-12 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS37120 3d301b45bb4a94dbee2cca2198c0798c 936 Gene3D G3DSA:3.40.50.410 87 275 7.0E-19 T 29-03-2018 IPR002035 von Willebrand factor, type A SMALA_RS37120 3d301b45bb4a94dbee2cca2198c0798c 936 SMART SM00327 86 268 2.1E-5 T 29-03-2018 IPR002035 von Willebrand factor, type A SMALA_RS10380 689b5654066d0fbb5cda4ece57b5c731 207 Pfam PF00174 Oxidoreductase molybdopterin binding domain 30 178 8.9E-28 T 29-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 SMALA_RS10380 689b5654066d0fbb5cda4ece57b5c731 207 Gene3D G3DSA:3.90.420.10 18 202 5.3E-45 T 29-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 SMALA_RS10380 689b5654066d0fbb5cda4ece57b5c731 207 SUPERFAMILY SSF56524 13 200 4.45E-52 T 29-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 SMALA_RS05765 ff4403ef943172799a82804fb95caa48 376 Pfam PF07730 Histidine kinase 176 239 2.0E-11 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMALA_RS05765 ff4403ef943172799a82804fb95caa48 376 Gene3D G3DSA:3.30.565.10 252 373 8.3E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS41115 e1f0b590396ed9ac4c2ebbbd02f09792 483 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 50 411 4.0E-78 T 29-03-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 SMALA_RS41115 e1f0b590396ed9ac4c2ebbbd02f09792 483 SUPERFAMILY SSF53383 10 471 5.52E-126 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS41115 e1f0b590396ed9ac4c2ebbbd02f09792 483 Gene3D G3DSA:1.20.1340.10 9 88 3.7E-13 T 29-03-2018 SMALA_RS41115 e1f0b590396ed9ac4c2ebbbd02f09792 483 Gene3D G3DSA:3.90.1150.10 365 471 1.8E-23 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS41115 e1f0b590396ed9ac4c2ebbbd02f09792 483 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 349 364 9.4E-13 T 29-03-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 SMALA_RS41115 e1f0b590396ed9ac4c2ebbbd02f09792 483 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 55 74 9.4E-13 T 29-03-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 SMALA_RS41115 e1f0b590396ed9ac4c2ebbbd02f09792 483 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 14 33 9.4E-13 T 29-03-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 SMALA_RS41115 e1f0b590396ed9ac4c2ebbbd02f09792 483 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 121 140 9.4E-13 T 29-03-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 SMALA_RS41115 e1f0b590396ed9ac4c2ebbbd02f09792 483 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 102 120 9.4E-13 T 29-03-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 SMALA_RS41115 e1f0b590396ed9ac4c2ebbbd02f09792 483 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 392 411 9.4E-13 T 29-03-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 SMALA_RS41115 e1f0b590396ed9ac4c2ebbbd02f09792 483 Gene3D G3DSA:3.40.640.10 95 364 2.3E-58 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS41115 e1f0b590396ed9ac4c2ebbbd02f09792 483 ProSitePatterns PS00392 DDC / GAD / HDC / TyrDC pyridoxal-phosphate attachment site. 295 316 - T 29-03-2018 IPR021115 Pyridoxal-phosphate binding site GO:0016831 SMALA_RS07235 fbd39f85612a730158f35b8423b71dd6 427 Gene3D G3DSA:1.20.1250.20 201 394 8.1E-11 T 29-03-2018 SMALA_RS07235 fbd39f85612a730158f35b8423b71dd6 427 SUPERFAMILY SSF103473 15 386 6.28E-30 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS07235 fbd39f85612a730158f35b8423b71dd6 427 Pfam PF07690 Major Facilitator Superfamily 18 329 6.0E-14 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS07235 fbd39f85612a730158f35b8423b71dd6 427 Gene3D G3DSA:1.20.1250.20 7 200 1.8E-18 T 29-03-2018 SMALA_RS06165 844bee0b9355fd3c8c6bd74b260ef047 146 Gene3D G3DSA:3.10.450.50 1 134 2.3E-27 T 29-03-2018 SMALA_RS06165 844bee0b9355fd3c8c6bd74b260ef047 146 Pfam PF12680 SnoaL-like domain 10 116 4.1E-19 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain SMALA_RS06165 844bee0b9355fd3c8c6bd74b260ef047 146 SUPERFAMILY SSF54427 4 132 6.17E-34 T 29-03-2018 IPR032710 NTF2-like domain SMALA_RS34520 f9cd3ca7519bb9dfc9d6b3ad91d2a950 579 Gene3D G3DSA:3.40.50.1220 191 335 4.7E-31 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain SMALA_RS34520 f9cd3ca7519bb9dfc9d6b3ad91d2a950 579 SUPERFAMILY SSF52518 359 550 5.9E-55 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold SMALA_RS34520 f9cd3ca7519bb9dfc9d6b3ad91d2a950 579 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 193 318 1.8E-27 T 29-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 SMALA_RS34520 f9cd3ca7519bb9dfc9d6b3ad91d2a950 579 Gene3D G3DSA:3.40.50.970 336 537 5.1E-38 T 29-03-2018 SMALA_RS34520 f9cd3ca7519bb9dfc9d6b3ad91d2a950 579 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 382 527 5.3E-37 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 SMALA_RS34520 f9cd3ca7519bb9dfc9d6b3ad91d2a950 579 Gene3D G3DSA:3.40.50.970 1 190 2.9E-40 T 29-03-2018 SMALA_RS34520 f9cd3ca7519bb9dfc9d6b3ad91d2a950 579 SUPERFAMILY SSF52518 2 172 7.85E-42 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold SMALA_RS34520 f9cd3ca7519bb9dfc9d6b3ad91d2a950 579 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 5 171 1.6E-41 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 SMALA_RS34520 f9cd3ca7519bb9dfc9d6b3ad91d2a950 579 SUPERFAMILY SSF52467 184 346 5.78E-38 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain SMALA_RS14915 c2070e122ae0716e1f844feb3403119b 367 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 144 235 9.4E-14 T 29-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 SMALA_RS14915 c2070e122ae0716e1f844feb3403119b 367 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 11 130 3.6E-21 T 29-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 SMALA_RS14915 c2070e122ae0716e1f844feb3403119b 367 SUPERFAMILY SSF55347 139 290 6.05E-28 T 29-03-2018 SMALA_RS14915 c2070e122ae0716e1f844feb3403119b 367 Gene3D G3DSA:3.30.360.10 144 364 5.7E-46 T 29-03-2018 SMALA_RS14915 c2070e122ae0716e1f844feb3403119b 367 Gene3D G3DSA:3.40.50.720 4 143 1.9E-33 T 29-03-2018 SMALA_RS14915 c2070e122ae0716e1f844feb3403119b 367 SUPERFAMILY SSF51735 8 167 4.55E-43 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS21440 b9a76a22367336f85a59f7957202f018 153 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 46 66 2.4E-13 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS21440 b9a76a22367336f85a59f7957202f018 153 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 12 23 2.4E-13 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS21440 b9a76a22367336f85a59f7957202f018 153 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 23 36 2.4E-13 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS21440 b9a76a22367336f85a59f7957202f018 153 Pfam PF13411 MerR HTH family regulatory protein 12 77 4.1E-17 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS21440 b9a76a22367336f85a59f7957202f018 153 Gene3D G3DSA:1.10.1660.10 66 145 9.2E-11 T 29-03-2018 SMALA_RS21440 b9a76a22367336f85a59f7957202f018 153 TIGRFAM TIGR01950 SoxR: redox-sensitive transcriptional activator SoxR 10 149 2.0E-63 T 29-03-2018 IPR010211 Redox-sensitive transcriptional activator SoxR GO:0003677|GO:0006355|GO:0006979|GO:0051537 SMALA_RS21440 b9a76a22367336f85a59f7957202f018 153 Gene3D G3DSA:1.10.1660.10 6 65 1.1E-20 T 29-03-2018 SMALA_RS21440 b9a76a22367336f85a59f7957202f018 153 SUPERFAMILY SSF46955 11 121 1.61E-29 T 29-03-2018 IPR009061 Putative DNA-binding domain SMALA_RS21440 b9a76a22367336f85a59f7957202f018 153 SMART SM00422 11 79 1.2E-24 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS24005 c605fefbf80031e5dbaa6924a47e30e0 288 Pfam PF00072 Response regulator receiver domain 6 69 5.2E-6 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS24005 c605fefbf80031e5dbaa6924a47e30e0 288 SMART SM00448 4 173 2.0E-10 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS24005 c605fefbf80031e5dbaa6924a47e30e0 288 SUPERFAMILY SSF52172 118 186 5.27E-8 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS24005 c605fefbf80031e5dbaa6924a47e30e0 288 Gene3D G3DSA:1.10.10.10 178 276 9.6E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS24005 c605fefbf80031e5dbaa6924a47e30e0 288 SUPERFAMILY SSF46894 202 271 4.08E-20 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS24005 c605fefbf80031e5dbaa6924a47e30e0 288 SMART SM00421 209 266 2.1E-20 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS24005 c605fefbf80031e5dbaa6924a47e30e0 288 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 212 226 1.2E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS24005 c605fefbf80031e5dbaa6924a47e30e0 288 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 242 254 1.2E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS24005 c605fefbf80031e5dbaa6924a47e30e0 288 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 226 242 1.2E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS24005 c605fefbf80031e5dbaa6924a47e30e0 288 Gene3D G3DSA:3.40.50.2300 1 177 9.3E-38 T 29-03-2018 SMALA_RS24005 c605fefbf80031e5dbaa6924a47e30e0 288 Pfam PF00196 Bacterial regulatory proteins, luxR family 211 266 9.9E-19 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS24005 c605fefbf80031e5dbaa6924a47e30e0 288 SUPERFAMILY SSF52172 3 63 3.66E-8 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS15825 7ad08d8a7671902fa02ae2042aa40f93 311 SUPERFAMILY SSF161111 6 219 1.31E-38 T 29-03-2018 SMALA_RS15825 7ad08d8a7671902fa02ae2042aa40f93 311 Gene3D G3DSA:1.20.1510.10 7 217 6.5E-33 T 29-03-2018 SMALA_RS15825 7ad08d8a7671902fa02ae2042aa40f93 311 Pfam PF01545 Cation efflux family 13 218 2.2E-34 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 SMALA_RS15825 7ad08d8a7671902fa02ae2042aa40f93 311 SUPERFAMILY SSF160240 222 295 4.45E-8 T 29-03-2018 SMALA_RS15825 7ad08d8a7671902fa02ae2042aa40f93 311 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 8 287 1.0E-39 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 SMALA_RS15825 7ad08d8a7671902fa02ae2042aa40f93 311 Gene3D G3DSA:3.30.70.1350 218 307 1.5E-8 T 29-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain SMALA_RS15195 c9c959e1a8fc58154781a7051793ffac 291 Gene3D G3DSA:3.40.50.1820 2 287 4.3E-43 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS15195 c9c959e1a8fc58154781a7051793ffac 291 Pfam PF00561 alpha/beta hydrolase fold 26 269 4.6E-19 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS15195 c9c959e1a8fc58154781a7051793ffac 291 SUPERFAMILY SSF53474 3 286 3.71E-46 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS15330 b6de4f777509082d86a2adef51abf26b 332 Gene3D G3DSA:1.20.58.370 28 73 1.1E-5 T 29-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain SMALA_RS15330 b6de4f777509082d86a2adef51abf26b 332 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 126 325 1.2E-8 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS15330 b6de4f777509082d86a2adef51abf26b 332 Gene3D G3DSA:1.10.3720.10 96 329 2.4E-39 T 29-03-2018 SMALA_RS15330 b6de4f777509082d86a2adef51abf26b 332 SUPERFAMILY SSF161098 88 320 1.83E-52 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS26815 1a312b2deb856b4286de3f304eba6aba 347 SUPERFAMILY SSF47323 208 346 1.5E-19 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMALA_RS26815 1a312b2deb856b4286de3f304eba6aba 347 SMART SM01016 4 97 2.5E-14 T 29-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 SMALA_RS26815 1a312b2deb856b4286de3f304eba6aba 347 Gene3D G3DSA:1.10.730.10 180 347 1.1E-38 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMALA_RS26815 1a312b2deb856b4286de3f304eba6aba 347 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 26 97 6.7E-10 T 29-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 SMALA_RS26815 1a312b2deb856b4286de3f304eba6aba 347 SUPERFAMILY SSF55190 22 109 2.75E-10 T 29-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 SMALA_RS26815 1a312b2deb856b4286de3f304eba6aba 347 SMART SM00836 214 347 6.6E-20 T 29-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 SMALA_RS26815 1a312b2deb856b4286de3f304eba6aba 347 Pfam PF05746 DALR anticodon binding domain 214 347 1.2E-19 T 29-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 SMALA_RS26815 1a312b2deb856b4286de3f304eba6aba 347 Gene3D G3DSA:3.30.1360.70 3 121 8.7E-23 T 29-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 SMALA_RS33620 3c8f5186b4d82deaf6fe75b3be780236 340 SUPERFAMILY SSF54919 176 273 1.22E-10 T 29-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SMALA_RS33620 3c8f5186b4d82deaf6fe75b3be780236 340 SUPERFAMILY SSF54919 43 101 1.22E-10 T 29-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SMALA_RS33620 3c8f5186b4d82deaf6fe75b3be780236 340 Gene3D G3DSA:3.30.70.141 27 275 5.9E-13 T 29-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SMALA_RS21850 ff81e0e9b3ba64803ae02fd2e8691bf7 293 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 31 272 3.2E-41 T 29-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 SMALA_RS21850 ff81e0e9b3ba64803ae02fd2e8691bf7 293 Gene3D G3DSA:3.40.710.10 6 293 2.1E-50 T 29-03-2018 SMALA_RS21850 ff81e0e9b3ba64803ae02fd2e8691bf7 293 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 153 166 1.1E-13 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 SMALA_RS21850 ff81e0e9b3ba64803ae02fd2e8691bf7 293 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 65 76 1.1E-13 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 SMALA_RS21850 ff81e0e9b3ba64803ae02fd2e8691bf7 293 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 120 137 1.1E-13 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 SMALA_RS21850 ff81e0e9b3ba64803ae02fd2e8691bf7 293 SUPERFAMILY SSF56601 36 291 7.95E-58 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMALA_RS34675 7d879e9461ddba871f24541f677f02ec 228 Gene3D G3DSA:1.10.287.950 18 195 7.7E-4 T 29-03-2018 SMALA_RS34060 bf3f9c3a3fac2f2eaf7f2aada5843db1 313 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 24 86 3.0E-7 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS34060 bf3f9c3a3fac2f2eaf7f2aada5843db1 313 SUPERFAMILY SSF50129 1 140 4.57E-31 T 29-03-2018 IPR011032 GroES-like SMALA_RS34060 bf3f9c3a3fac2f2eaf7f2aada5843db1 313 Gene3D G3DSA:3.90.180.10 1 138 4.8E-35 T 29-03-2018 SMALA_RS34060 bf3f9c3a3fac2f2eaf7f2aada5843db1 313 Gene3D G3DSA:3.90.180.10 235 312 6.3E-9 T 29-03-2018 SMALA_RS34060 bf3f9c3a3fac2f2eaf7f2aada5843db1 313 SUPERFAMILY SSF51735 110 286 7.36E-29 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS34060 bf3f9c3a3fac2f2eaf7f2aada5843db1 313 SMART SM00829 7 310 5.1E-18 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS34060 bf3f9c3a3fac2f2eaf7f2aada5843db1 313 Gene3D G3DSA:3.40.50.720 139 234 4.8E-20 T 29-03-2018 SMALA_RS34060 bf3f9c3a3fac2f2eaf7f2aada5843db1 313 Pfam PF13602 Zinc-binding dehydrogenase 179 310 2.0E-20 T 29-03-2018 SMALA_RS00545 93e7f33e67aa29d2be86f6aa2d4f4839 302 Gene3D G3DSA:1.10.600.10 9 301 1.0E-42 T 29-03-2018 IPR008949 Isoprenoid synthase domain SMALA_RS00545 93e7f33e67aa29d2be86f6aa2d4f4839 302 SUPERFAMILY SSF48576 21 297 1.18E-26 T 29-03-2018 IPR008949 Isoprenoid synthase domain SMALA_RS00545 93e7f33e67aa29d2be86f6aa2d4f4839 302 Pfam PF00494 Squalene/phytoene synthase 35 274 3.0E-25 T 29-03-2018 IPR002060 Squalene/phytoene synthase GO:0009058|GO:0016740 SMALA_RS23965 d2c6577d7daa8fe5582b329befae56ad 606 ProSitePatterns PS00211 ABC transporters family signature. 419 433 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS23965 d2c6577d7daa8fe5582b329befae56ad 606 SUPERFAMILY SSF52540 295 488 8.56E-40 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS23965 d2c6577d7daa8fe5582b329befae56ad 606 Pfam PF16326 ABC transporter C-terminal domain 542 603 2.6E-8 T 29-03-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 SMALA_RS23965 d2c6577d7daa8fe5582b329befae56ad 606 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS23965 d2c6577d7daa8fe5582b329befae56ad 606 Pfam PF00005 ABC transporter 21 159 2.8E-22 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS23965 d2c6577d7daa8fe5582b329befae56ad 606 Pfam PF00005 ABC transporter 306 447 1.0E-20 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS23965 d2c6577d7daa8fe5582b329befae56ad 606 SMART SM00382 315 491 1.9E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS23965 d2c6577d7daa8fe5582b329befae56ad 606 SMART SM00382 30 213 3.3E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS23965 d2c6577d7daa8fe5582b329befae56ad 606 Gene3D G3DSA:3.40.50.300 2 268 2.0E-48 T 29-03-2018 SMALA_RS23965 d2c6577d7daa8fe5582b329befae56ad 606 SUPERFAMILY SSF52540 5 208 7.53E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS23965 d2c6577d7daa8fe5582b329befae56ad 606 Pfam PF12848 ABC transporter 198 257 6.9E-8 T 29-03-2018 IPR032781 ABC-transporter extension domain SMALA_RS23965 d2c6577d7daa8fe5582b329befae56ad 606 Gene3D G3DSA:3.40.50.300 270 547 5.8E-48 T 29-03-2018 SMALA_RS17590 6e941423087e49ea6f12c5063cfdf86d 198 SUPERFAMILY SSF46689 3 79 1.23E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS17590 6e941423087e49ea6f12c5063cfdf86d 198 Gene3D G3DSA:1.10.357.10 1 193 8.6E-29 T 29-03-2018 SMALA_RS17590 6e941423087e49ea6f12c5063cfdf86d 198 SUPERFAMILY SSF48498 76 184 5.66E-15 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS17590 6e941423087e49ea6f12c5063cfdf86d 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 1.1E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS17590 6e941423087e49ea6f12c5063cfdf86d 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 1.1E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS17590 6e941423087e49ea6f12c5063cfdf86d 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 59 6.4E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS21790 63555f07b0f1dfbb7c6c9caed6cc58d9 347 SUPERFAMILY SSF51735 2 317 1.36E-34 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS21790 63555f07b0f1dfbb7c6c9caed6cc58d9 347 Gene3D G3DSA:3.40.50.720 1 321 2.9E-31 T 29-03-2018 SMALA_RS21790 63555f07b0f1dfbb7c6c9caed6cc58d9 347 Pfam PF01370 NAD dependent epimerase/dehydratase family 5 237 1.7E-17 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 SMALA_RS02460 3a56ed8953f41bde63e5834a4a604f4e 352 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 58 117 1.2E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS02460 3a56ed8953f41bde63e5834a4a604f4e 352 Gene3D G3DSA:3.40.190.10 243 324 2.6E-18 T 29-03-2018 SMALA_RS02460 3a56ed8953f41bde63e5834a4a604f4e 352 SUPERFAMILY SSF46785 51 162 2.09E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS02460 3a56ed8953f41bde63e5834a4a604f4e 352 Gene3D G3DSA:1.10.10.10 51 134 4.8E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS02460 3a56ed8953f41bde63e5834a4a604f4e 352 Gene3D G3DSA:3.40.190.10 135 242 5.5E-22 T 29-03-2018 SMALA_RS02460 3a56ed8953f41bde63e5834a4a604f4e 352 Pfam PF03466 LysR substrate binding domain 142 350 2.0E-34 T 29-03-2018 IPR005119 LysR, substrate-binding SMALA_RS02460 3a56ed8953f41bde63e5834a4a604f4e 352 SUPERFAMILY SSF53850 141 351 3.58E-37 T 29-03-2018 SMALA_RS06255 53d69a743893281f9ccef3b79e4493e8 279 SUPERFAMILY SSF47413 30 81 9.15E-7 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS06255 53d69a743893281f9ccef3b79e4493e8 279 SMART SM00530 10 82 3.5E-8 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS06255 53d69a743893281f9ccef3b79e4493e8 279 Pfam PF13560 Helix-turn-helix domain 7 85 6.8E-16 T 29-03-2018 SMALA_RS06255 53d69a743893281f9ccef3b79e4493e8 279 Gene3D G3DSA:1.10.260.40 2 82 4.1E-14 T 29-03-2018 SMALA_RS01190 16ea8139cef2a8d3c9a6ad414439a47d 400 PRINTS PR00344 Bacterial sensor protein C-terminal signature 370 383 2.8E-5 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS01190 16ea8139cef2a8d3c9a6ad414439a47d 400 PRINTS PR00344 Bacterial sensor protein C-terminal signature 346 364 2.8E-5 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS01190 16ea8139cef2a8d3c9a6ad414439a47d 400 PRINTS PR00344 Bacterial sensor protein C-terminal signature 323 337 2.8E-5 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS01190 16ea8139cef2a8d3c9a6ad414439a47d 400 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 292 384 4.0E-7 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS01190 16ea8139cef2a8d3c9a6ad414439a47d 400 SUPERFAMILY SSF55874 258 383 7.28E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS01190 16ea8139cef2a8d3c9a6ad414439a47d 400 SMART SM00387 287 386 0.0063 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS01190 16ea8139cef2a8d3c9a6ad414439a47d 400 Gene3D G3DSA:3.30.565.10 242 389 2.5E-23 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS01190 16ea8139cef2a8d3c9a6ad414439a47d 400 PIRSF PIRSF037434 1 390 1.5E-128 T 29-03-2018 IPR017205 Signal transduction histidine kinase, ChrS SMALA_RS01190 16ea8139cef2a8d3c9a6ad414439a47d 400 Pfam PF07730 Histidine kinase 183 250 2.9E-17 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMALA_RS34625 6f34dcbca2668c6a2bafb5b452d33309 529 Pfam PF09423 PhoD-like phosphatase 161 508 1.6E-78 T 29-03-2018 IPR018946 Alkaline phosphatase D-related SMALA_RS34625 6f34dcbca2668c6a2bafb5b452d33309 529 Gene3D G3DSA:3.60.21.10 149 525 4.6E-38 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SMALA_RS34625 6f34dcbca2668c6a2bafb5b452d33309 529 Pfam PF16655 PhoD-like phosphatase, N-terminal domain 54 131 1.0E-13 T 29-03-2018 IPR032093 Phospholipase D, N-terminal SMALA_RS34625 6f34dcbca2668c6a2bafb5b452d33309 529 SUPERFAMILY SSF56300 149 522 3.14E-38 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SMALA_RS09485 160e42ea52844688e3fb90d5ec498c37 266 Pfam PF12802 MarR family 34 78 1.5E-6 T 29-03-2018 SMALA_RS09485 160e42ea52844688e3fb90d5ec498c37 266 Gene3D G3DSA:1.10.10.10 11 118 3.6E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS09485 160e42ea52844688e3fb90d5ec498c37 266 SUPERFAMILY SSF46785 30 220 1.14E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS20425 fa4908f853c160ca29de80863e37c675 338 Pfam PF00571 CBS domain 286 333 4.4E-4 T 29-03-2018 IPR000644 CBS domain SMALA_RS20425 fa4908f853c160ca29de80863e37c675 338 Gene3D G3DSA:3.10.580.10 201 338 3.1E-23 T 29-03-2018 SMALA_RS20425 fa4908f853c160ca29de80863e37c675 338 SUPERFAMILY SSF54631 205 334 1.23E-19 T 29-03-2018 SMALA_RS20425 fa4908f853c160ca29de80863e37c675 338 Pfam PF01595 Domain of unknown function DUF21 10 197 8.1E-41 T 29-03-2018 IPR002550 Domain of unknown function DUF21 SMALA_RS33415 4ad44473217bcaf33db19fc68303137d 592 ProSitePatterns PS00455 Putative AMP-binding domain signature. 169 180 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS33415 4ad44473217bcaf33db19fc68303137d 592 SUPERFAMILY SSF56801 11 565 1.44E-101 T 29-03-2018 SMALA_RS33415 4ad44473217bcaf33db19fc68303137d 592 Gene3D G3DSA:3.40.50.980 171 338 1.9E-32 T 29-03-2018 SMALA_RS33415 4ad44473217bcaf33db19fc68303137d 592 Pfam PF00501 AMP-binding enzyme 18 457 2.1E-84 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS33415 4ad44473217bcaf33db19fc68303137d 592 Gene3D G3DSA:3.30.300.30 453 563 8.9E-13 T 29-03-2018 SMALA_RS33415 4ad44473217bcaf33db19fc68303137d 592 Gene3D G3DSA:2.30.38.10 370 451 7.8E-21 T 29-03-2018 SMALA_RS33415 4ad44473217bcaf33db19fc68303137d 592 Gene3D G3DSA:3.40.50.980 8 170 3.2E-31 T 29-03-2018 SMALA_RS21640 08be48e35c737804b07b1cb9b2136e11 235 Pfam PF00072 Response regulator receiver domain 6 115 1.2E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS21640 08be48e35c737804b07b1cb9b2136e11 235 SUPERFAMILY SSF52172 4 123 9.68E-40 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS21640 08be48e35c737804b07b1cb9b2136e11 235 SMART SM00862 162 233 1.4E-24 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS21640 08be48e35c737804b07b1cb9b2136e11 235 SUPERFAMILY SSF46894 139 233 1.25E-27 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS21640 08be48e35c737804b07b1cb9b2136e11 235 Pfam PF00486 Transcriptional regulatory protein, C terminal 162 233 8.0E-23 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS21640 08be48e35c737804b07b1cb9b2136e11 235 Gene3D G3DSA:1.10.10.10 147 235 3.4E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS21640 08be48e35c737804b07b1cb9b2136e11 235 Gene3D G3DSA:3.40.50.2300 1 146 2.3E-36 T 29-03-2018 SMALA_RS21640 08be48e35c737804b07b1cb9b2136e11 235 SMART SM00448 4 114 2.9E-40 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS15425 ac64bf3ab4e0f15cc661868f7f4ec46e 294 Pfam PF00561 alpha/beta hydrolase fold 39 151 2.2E-24 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS15425 ac64bf3ab4e0f15cc661868f7f4ec46e 294 PRINTS PR00412 Epoxide hydrolase signature 121 134 7.3E-7 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS15425 ac64bf3ab4e0f15cc661868f7f4ec46e 294 PRINTS PR00412 Epoxide hydrolase signature 44 62 7.3E-7 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS15425 ac64bf3ab4e0f15cc661868f7f4ec46e 294 PRINTS PR00412 Epoxide hydrolase signature 107 120 7.3E-7 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS15425 ac64bf3ab4e0f15cc661868f7f4ec46e 294 PRINTS PR00111 Alpha/beta hydrolase fold signature 121 134 6.0E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS15425 ac64bf3ab4e0f15cc661868f7f4ec46e 294 PRINTS PR00111 Alpha/beta hydrolase fold signature 63 78 6.0E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS15425 ac64bf3ab4e0f15cc661868f7f4ec46e 294 PRINTS PR00111 Alpha/beta hydrolase fold signature 107 120 6.0E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS15425 ac64bf3ab4e0f15cc661868f7f4ec46e 294 SUPERFAMILY SSF53474 16 289 7.12E-62 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS15425 ac64bf3ab4e0f15cc661868f7f4ec46e 294 Gene3D G3DSA:3.40.50.1820 8 294 2.6E-45 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS38340 7a3afe451cc530c25594259ed5e18466 484 SMART SM00191 33 92 0.15 T 29-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMALA_RS38340 7a3afe451cc530c25594259ed5e18466 484 SMART SM00191 408 465 6.6E-8 T 29-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMALA_RS38340 7a3afe451cc530c25594259ed5e18466 484 SMART SM00191 337 396 1.5E-7 T 29-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMALA_RS38340 7a3afe451cc530c25594259ed5e18466 484 SMART SM00191 104 152 31.0 T 29-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMALA_RS38340 7a3afe451cc530c25594259ed5e18466 484 Gene3D G3DSA:2.60.40.680 335 430 3.5E-21 T 29-03-2018 SMALA_RS38340 7a3afe451cc530c25594259ed5e18466 484 Gene3D G3DSA:2.60.40.680 132 186 1.9E-6 T 29-03-2018 SMALA_RS38340 7a3afe451cc530c25594259ed5e18466 484 Gene3D G3DSA:2.60.40.680 13 131 6.6E-17 T 29-03-2018 SMALA_RS38340 7a3afe451cc530c25594259ed5e18466 484 Gene3D G3DSA:2.60.40.680 431 482 2.1E-5 T 29-03-2018 SMALA_RS38340 7a3afe451cc530c25594259ed5e18466 484 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 116 177 2.4E-8 T 29-03-2018 SMALA_RS38340 7a3afe451cc530c25594259ed5e18466 484 Pfam PF01839 FG-GAP repeat 412 449 1.5E-7 T 29-03-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 SMALA_RS38340 7a3afe451cc530c25594259ed5e18466 484 Pfam PF01839 FG-GAP repeat 341 377 1.5E-9 T 29-03-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 SMALA_RS38340 7a3afe451cc530c25594259ed5e18466 484 Pfam PF01839 FG-GAP repeat 45 75 3.4E-5 T 29-03-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 SMALA_RS38340 7a3afe451cc530c25594259ed5e18466 484 Gene3D G3DSA:2.130.10.130 187 334 1.2E-11 T 29-03-2018 SMALA_RS38340 7a3afe451cc530c25594259ed5e18466 484 SUPERFAMILY SSF69318 44 389 2.18E-47 T 29-03-2018 SMALA_RS38340 7a3afe451cc530c25594259ed5e18466 484 SUPERFAMILY SSF69318 378 475 3.14E-11 T 29-03-2018 SMALA_RS06905 0d120e5336964b42c5a829137cd49d79 446 Pfam PF00107 Zinc-binding dehydrogenase 228 372 2.5E-34 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMALA_RS06905 0d120e5336964b42c5a829137cd49d79 446 Gene3D G3DSA:3.90.180.10 2 408 3.8E-61 T 29-03-2018 SMALA_RS06905 0d120e5336964b42c5a829137cd49d79 446 TIGRFAM TIGR01751 crot-CoA-red: crotonyl-CoA carboxylase/reductase 25 420 1.3E-174 T 29-03-2018 IPR010085 Crotonyl-CoA reductase GO:0043880 KEGG: 00650+1.3.1.86 SMALA_RS06905 0d120e5336964b42c5a829137cd49d79 446 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 59 182 1.1E-6 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS06905 0d120e5336964b42c5a829137cd49d79 446 SUPERFAMILY SSF51735 187 377 1.66E-32 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS06905 0d120e5336964b42c5a829137cd49d79 446 SUPERFAMILY SSF50129 42 222 4.86E-29 T 29-03-2018 IPR011032 GroES-like SMALA_RS06905 0d120e5336964b42c5a829137cd49d79 446 SMART SM00829 41 407 2.9E-10 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS10050 affe7a2bb93d0c752b37277b1adcaaab 136 Pfam PF01042 Endoribonuclease L-PSP 21 129 8.1E-18 T 29-03-2018 IPR006175 YjgF/YER057c/UK114 family SMALA_RS10050 affe7a2bb93d0c752b37277b1adcaaab 136 Gene3D G3DSA:3.30.1330.40 5 130 3.1E-28 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SMALA_RS10050 affe7a2bb93d0c752b37277b1adcaaab 136 SUPERFAMILY SSF55298 8 132 1.08E-26 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SMALA_RS04985 06eac450c7c457116be04daa5d9851b2 268 SUPERFAMILY SSF49879 32 79 3.94E-7 T 29-03-2018 IPR008984 SMAD/FHA domain GO:0005515 SMALA_RS04985 06eac450c7c457116be04daa5d9851b2 268 Gene3D G3DSA:2.60.200.20 25 111 2.3E-8 T 29-03-2018 SMALA_RS01705 82912792d70dbb5c750a4fc780b57fc8 456 SUPERFAMILY SSF103473 12 447 5.23E-72 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS01705 82912792d70dbb5c750a4fc780b57fc8 456 Gene3D G3DSA:1.20.1250.20 240 454 1.3E-23 T 29-03-2018 SMALA_RS01705 82912792d70dbb5c750a4fc780b57fc8 456 ProSitePatterns PS00217 Sugar transport proteins signature 2. 126 151 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMALA_RS01705 82912792d70dbb5c750a4fc780b57fc8 456 Gene3D G3DSA:1.20.1250.20 20 222 3.0E-32 T 29-03-2018 SMALA_RS01705 82912792d70dbb5c750a4fc780b57fc8 456 Pfam PF00083 Sugar (and other) transporter 32 451 1.7E-60 T 29-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 SMALA_RS02250 0557b55d6f79069542dfa7f95ec6243b 274 Gene3D G3DSA:3.20.80.10 127 274 4.8E-29 T 29-03-2018 IPR011256 Regulatory factor, effector binding domain SMALA_RS02250 0557b55d6f79069542dfa7f95ec6243b 274 Pfam PF13411 MerR HTH family regulatory protein 2 71 1.6E-14 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS02250 0557b55d6f79069542dfa7f95ec6243b 274 Gene3D G3DSA:1.10.1660.10 59 126 4.7E-10 T 29-03-2018 SMALA_RS02250 0557b55d6f79069542dfa7f95ec6243b 274 SMART SM00422 2 72 5.6E-18 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS02250 0557b55d6f79069542dfa7f95ec6243b 274 Gene3D G3DSA:1.10.1660.10 1 58 9.2E-20 T 29-03-2018 SMALA_RS02250 0557b55d6f79069542dfa7f95ec6243b 274 SMART SM00871 119 272 1.6E-15 T 29-03-2018 IPR010499 Bacterial transcription activator, effector binding SMALA_RS02250 0557b55d6f79069542dfa7f95ec6243b 274 Pfam PF06445 GyrI-like small molecule binding domain 121 271 5.1E-12 T 29-03-2018 IPR029442 GyrI-like small molecule binding domain SMALA_RS02250 0557b55d6f79069542dfa7f95ec6243b 274 SUPERFAMILY SSF55136 120 272 5.76E-20 T 29-03-2018 SMALA_RS02250 0557b55d6f79069542dfa7f95ec6243b 274 SUPERFAMILY SSF46955 2 100 1.32E-23 T 29-03-2018 IPR009061 Putative DNA-binding domain SMALA_RS13890 38bf6352963fe8ddeaa435e7c7ae2039 356 Pfam PF02653 Branched-chain amino acid transport system / permease component 66 342 3.4E-55 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 SMALA_RS13890 38bf6352963fe8ddeaa435e7c7ae2039 356 Gene3D G3DSA:1.10.3470.10 55 351 1.1E-20 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SMALA_RS38260 01d31aaecb4c710ef31b5602ecb16544 270 Pfam PF12697 Alpha/beta hydrolase family 22 258 1.2E-17 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS38260 01d31aaecb4c710ef31b5602ecb16544 270 PRINTS PR00412 Epoxide hydrolase signature 208 224 9.9E-6 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS38260 01d31aaecb4c710ef31b5602ecb16544 270 PRINTS PR00412 Epoxide hydrolase signature 47 62 9.9E-6 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS38260 01d31aaecb4c710ef31b5602ecb16544 270 PRINTS PR00412 Epoxide hydrolase signature 241 263 9.9E-6 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS38260 01d31aaecb4c710ef31b5602ecb16544 270 SUPERFAMILY SSF53474 1 264 1.29E-58 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS38260 01d31aaecb4c710ef31b5602ecb16544 270 Gene3D G3DSA:3.40.50.1820 2 269 6.4E-52 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS38305 ee77a4a53e7d35ed2b900a357009193c 264 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 44 259 9.2E-64 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SMALA_RS38305 ee77a4a53e7d35ed2b900a357009193c 264 SMART SM00062 42 261 1.4E-69 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SMALA_RS38305 ee77a4a53e7d35ed2b900a357009193c 264 Gene3D G3DSA:3.40.190.10 185 264 3.5E-13 T 29-03-2018 SMALA_RS38305 ee77a4a53e7d35ed2b900a357009193c 264 SUPERFAMILY SSF53850 14 260 3.11E-65 T 29-03-2018 SMALA_RS38305 ee77a4a53e7d35ed2b900a357009193c 264 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 64 77 - T 29-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 SMALA_RS38305 ee77a4a53e7d35ed2b900a357009193c 264 Gene3D G3DSA:3.40.190.10 35 184 5.7E-38 T 29-03-2018 SMALA_RS21360 107effb33d51d820e0318fc1578b7777 375 PIRSF PIRSF002756 10 375 8.1E-119 T 29-03-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 SMALA_RS21360 107effb33d51d820e0318fc1578b7777 375 Pfam PF12849 PBP superfamily domain 54 345 6.4E-58 T 29-03-2018 IPR024370 PBP domain SMALA_RS21360 107effb33d51d820e0318fc1578b7777 375 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 59 373 4.8E-82 T 29-03-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 SMALA_RS21360 107effb33d51d820e0318fc1578b7777 375 Gene3D G3DSA:3.40.190.10 57 227 3.3E-30 T 29-03-2018 SMALA_RS21360 107effb33d51d820e0318fc1578b7777 375 Gene3D G3DSA:3.40.190.10 231 375 3.2E-25 T 29-03-2018 SMALA_RS21360 107effb33d51d820e0318fc1578b7777 375 SUPERFAMILY SSF53850 57 375 9.59E-87 T 29-03-2018 SMALA_RS32245 bee0c417cfbf50021dfbe6a713015cf1 455 SUPERFAMILY SSF54368 10 119 3.92E-16 T 29-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SMALA_RS32245 bee0c417cfbf50021dfbe6a713015cf1 455 Gene3D G3DSA:3.10.20.70 16 116 5.1E-21 T 29-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SMALA_RS32245 bee0c417cfbf50021dfbe6a713015cf1 455 SUPERFAMILY SSF55931 122 453 5.4E-102 T 29-03-2018 SMALA_RS32245 bee0c417cfbf50021dfbe6a713015cf1 455 Pfam PF00120 Glutamine synthetase, catalytic domain 121 448 1.3E-103 T 29-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SMALA_RS32245 bee0c417cfbf50021dfbe6a713015cf1 455 Gene3D G3DSA:3.30.590.10 117 455 2.4E-103 T 29-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 SMALA_RS32245 bee0c417cfbf50021dfbe6a713015cf1 455 SMART SM01230 120 373 2.1E-103 T 29-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SMALA_RS33765 4631da3e67124e1e0adcc28ca464b3a1 419 Pfam PF00480 ROK family 94 382 1.6E-38 T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 SMALA_RS33765 4631da3e67124e1e0adcc28ca464b3a1 419 Gene3D G3DSA:3.30.420.40 84 199 1.3E-16 T 29-03-2018 SMALA_RS33765 4631da3e67124e1e0adcc28ca464b3a1 419 Gene3D G3DSA:3.30.420.40 200 398 8.1E-47 T 29-03-2018 SMALA_RS33765 4631da3e67124e1e0adcc28ca464b3a1 419 SUPERFAMILY SSF46785 20 81 1.7E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS33765 4631da3e67124e1e0adcc28ca464b3a1 419 SUPERFAMILY SSF53067 92 387 4.92E-44 T 29-03-2018 SMALA_RS33765 4631da3e67124e1e0adcc28ca464b3a1 419 Pfam PF13412 Winged helix-turn-helix DNA-binding 27 67 1.2E-5 T 29-03-2018 SMALA_RS33765 4631da3e67124e1e0adcc28ca464b3a1 419 Gene3D G3DSA:1.10.10.10 14 83 1.5E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS36585 5ffe7ee1bb590824b3b72a09015e6a51 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 2.7E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS36585 5ffe7ee1bb590824b3b72a09015e6a51 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.7E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS36585 5ffe7ee1bb590824b3b72a09015e6a51 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 2.7E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS36585 5ffe7ee1bb590824b3b72a09015e6a51 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 2.7E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS36585 5ffe7ee1bb590824b3b72a09015e6a51 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 2.7E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS36585 5ffe7ee1bb590824b3b72a09015e6a51 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 220 240 2.7E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS36585 5ffe7ee1bb590824b3b72a09015e6a51 259 Gene3D G3DSA:3.40.50.720 1 49 2.4E-9 T 29-03-2018 SMALA_RS36585 5ffe7ee1bb590824b3b72a09015e6a51 259 Gene3D G3DSA:3.40.50.720 50 259 1.2E-48 T 29-03-2018 SMALA_RS36585 5ffe7ee1bb590824b3b72a09015e6a51 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 254 1.1E-48 T 29-03-2018 SMALA_RS36585 5ffe7ee1bb590824b3b72a09015e6a51 259 SUPERFAMILY SSF51735 6 255 2.56E-64 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS36585 5ffe7ee1bb590824b3b72a09015e6a51 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 1.8E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS36585 5ffe7ee1bb590824b3b72a09015e6a51 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 1.8E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS36585 5ffe7ee1bb590824b3b72a09015e6a51 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 1.8E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS04390 211956c3b50d28b33eeb10851dd15d27 288 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 187 283 1.7E-28 T 29-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 SMALA_RS04390 211956c3b50d28b33eeb10851dd15d27 288 Gene3D G3DSA:3.40.50.720 3 185 2.4E-39 T 29-03-2018 SMALA_RS04390 211956c3b50d28b33eeb10851dd15d27 288 SUPERFAMILY SSF48179 186 285 1.28E-28 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMALA_RS04390 211956c3b50d28b33eeb10851dd15d27 288 Gene3D G3DSA:1.10.1040.10 186 288 5.2E-27 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMALA_RS04390 211956c3b50d28b33eeb10851dd15d27 288 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 11 184 1.9E-44 T 29-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 SMALA_RS04390 211956c3b50d28b33eeb10851dd15d27 288 PIRSF PIRSF000105 3 288 6.1E-79 T 29-03-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 SMALA_RS04390 211956c3b50d28b33eeb10851dd15d27 288 SUPERFAMILY SSF51735 9 186 6.53E-38 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS18320 e9005f72421506e2c64571882e7a3c54 666 Gene3D G3DSA:3.30.565.10 429 663 3.0E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS18320 e9005f72421506e2c64571882e7a3c54 666 SUPERFAMILY SSF55874 538 661 1.44E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS18320 e9005f72421506e2c64571882e7a3c54 666 SUPERFAMILY SSF55781 36 182 2.01E-20 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS18320 e9005f72421506e2c64571882e7a3c54 666 SMART SM00387 571 664 1.0E-5 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS18320 e9005f72421506e2c64571882e7a3c54 666 Gene3D G3DSA:3.30.450.40 13 185 2.4E-26 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS18320 e9005f72421506e2c64571882e7a3c54 666 Pfam PF07730 Histidine kinase 428 534 3.5E-11 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMALA_RS18320 e9005f72421506e2c64571882e7a3c54 666 SUPERFAMILY SSF55781 289 423 2.01E-11 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS18320 e9005f72421506e2c64571882e7a3c54 666 Gene3D G3DSA:3.30.450.40 297 428 4.4E-16 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS18320 e9005f72421506e2c64571882e7a3c54 666 SMART SM00065 34 179 2.1E-11 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS18320 e9005f72421506e2c64571882e7a3c54 666 SMART SM00065 287 421 0.036 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS18320 e9005f72421506e2c64571882e7a3c54 666 Pfam PF13185 GAF domain 34 169 2.6E-12 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS18320 e9005f72421506e2c64571882e7a3c54 666 Gene3D G3DSA:2.160.20.50 186 296 8.7E-4 T 29-03-2018 SMALA_RS27720 d719dfdad4b4e1f69f44d43a995f502a 174 SUPERFAMILY SSF55021 80 161 2.26E-26 T 29-03-2018 SMALA_RS27720 d719dfdad4b4e1f69f44d43a995f502a 174 Pfam PF10369 Small subunit of acetolactate synthase 85 158 3.3E-29 T 29-03-2018 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 SMALA_RS27720 d719dfdad4b4e1f69f44d43a995f502a 174 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 3 158 6.8E-61 T 29-03-2018 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 SMALA_RS27720 d719dfdad4b4e1f69f44d43a995f502a 174 Gene3D G3DSA:3.30.70.260 1 88 1.8E-24 T 29-03-2018 SMALA_RS27720 d719dfdad4b4e1f69f44d43a995f502a 174 SUPERFAMILY SSF55021 3 75 3.49E-22 T 29-03-2018 SMALA_RS27720 d719dfdad4b4e1f69f44d43a995f502a 174 Gene3D G3DSA:3.30.70.1150 89 161 1.8E-30 T 29-03-2018 SMALA_RS27720 d719dfdad4b4e1f69f44d43a995f502a 174 Pfam PF01842 ACT domain 4 69 3.2E-16 T 29-03-2018 IPR002912 ACT domain SMALA_RS27720 d719dfdad4b4e1f69f44d43a995f502a 174 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 3 77 3.0E-34 T 29-03-2018 SMALA_RS32155 8dcefcec5e308e86b4f39300b489283b 156 Gene3D G3DSA:3.30.565.10 27 155 6.8E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS32155 8dcefcec5e308e86b4f39300b489283b 156 SUPERFAMILY SSF55874 57 148 1.37E-10 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS32155 8dcefcec5e308e86b4f39300b489283b 156 Pfam PF13581 Histidine kinase-like ATPase domain 35 142 1.5E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS15470 47bb42e1df486d7a782974d58fd7f989 308 SUPERFAMILY SSF50129 3 140 6.45E-19 T 29-03-2018 IPR011032 GroES-like SMALA_RS15470 47bb42e1df486d7a782974d58fd7f989 308 Pfam PF00107 Zinc-binding dehydrogenase 144 247 1.1E-12 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMALA_RS15470 47bb42e1df486d7a782974d58fd7f989 308 SMART SM00829 9 305 2.0E-8 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS15470 47bb42e1df486d7a782974d58fd7f989 308 Gene3D G3DSA:3.40.50.720 143 250 5.2E-17 T 29-03-2018 SMALA_RS15470 47bb42e1df486d7a782974d58fd7f989 308 SUPERFAMILY SSF51735 111 253 7.05E-28 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS15470 47bb42e1df486d7a782974d58fd7f989 308 Gene3D G3DSA:3.90.180.10 1 142 1.3E-29 T 29-03-2018 SMALA_RS37825 a6828bb1e2f7166e9addb0d26992ce3c 3375 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1758 2008 9.4E-90 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS37825 a6828bb1e2f7166e9addb0d26992ce3c 3375 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 33 282 4.8E-90 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS37825 a6828bb1e2f7166e9addb0d26992ce3c 3375 SUPERFAMILY SSF51735 1218 1364 3.7E-22 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS37825 a6828bb1e2f7166e9addb0d26992ce3c 3375 Gene3D G3DSA:1.10.1200.10 3194 3304 1.1E-18 T 29-03-2018 SMALA_RS37825 a6828bb1e2f7166e9addb0d26992ce3c 3375 Pfam PF08990 Erythronolide synthase docking 3 26 3.1E-8 T 29-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 SMALA_RS37825 a6828bb1e2f7166e9addb0d26992ce3c 3375 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2296 2598 5.0E-133 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS37825 a6828bb1e2f7166e9addb0d26992ce3c 3375 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 566 864 1.1E-124 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS37825 a6828bb1e2f7166e9addb0d26992ce3c 3375 SUPERFAMILY SSF55048 690 755 4.19E-14 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS37825 a6828bb1e2f7166e9addb0d26992ce3c 3375 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2016 2133 2.3E-43 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS37825 a6828bb1e2f7166e9addb0d26992ce3c 3375 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 290 408 3.1E-43 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS37825 a6828bb1e2f7166e9addb0d26992ce3c 3375 Gene3D G3DSA:3.40.366.10 752 871 2.5E-28 T 29-03-2018 SMALA_RS37825 a6828bb1e2f7166e9addb0d26992ce3c 3375 Gene3D G3DSA:3.40.366.10 2478 2605 1.2E-29 T 29-03-2018 SMALA_RS37825 a6828bb1e2f7166e9addb0d26992ce3c 3375 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1688 1703 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS37825 a6828bb1e2f7166e9addb0d26992ce3c 3375 Pfam PF00550 Phosphopantetheine attachment site 1672 1729 3.9E-9 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS37825 a6828bb1e2f7166e9addb0d26992ce3c 3375 Pfam PF00550 Phosphopantetheine attachment site 3227 3292 1.5E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS37825 a6828bb1e2f7166e9addb0d26992ce3c 3375 Gene3D G3DSA:3.40.47.10 2023 2184 4.3E-60 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS37825 a6828bb1e2f7166e9addb0d26992ce3c 3375 Gene3D G3DSA:3.40.47.10 297 459 7.3E-63 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS37825 a6828bb1e2f7166e9addb0d26992ce3c 3375 SUPERFAMILY SSF51735 1374 1626 3.33E-40 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS37825 a6828bb1e2f7166e9addb0d26992ce3c 3375 Pfam PF14765 Polyketide synthase dehydratase 931 1210 1.3E-54 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37825 a6828bb1e2f7166e9addb0d26992ce3c 3375 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3251 3266 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS37825 a6828bb1e2f7166e9addb0d26992ce3c 3375 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2937 3116 5.0E-59 T 29-03-2018 SMALA_RS37825 a6828bb1e2f7166e9addb0d26992ce3c 3375 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1375 1555 7.5E-54 T 29-03-2018 SMALA_RS37825 a6828bb1e2f7166e9addb0d26992ce3c 3375 SMART SM00823 Phosphopantetheine attachment site 1661 1733 3.7E-31 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37825 a6828bb1e2f7166e9addb0d26992ce3c 3375 SMART SM00823 Phosphopantetheine attachment site 3224 3296 2.7E-27 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37825 a6828bb1e2f7166e9addb0d26992ce3c 3375 Gene3D G3DSA:3.40.50.720 1374 1617 3.2E-40 T 29-03-2018 SMALA_RS37825 a6828bb1e2f7166e9addb0d26992ce3c 3375 Gene3D G3DSA:3.40.50.720 2929 3189 1.4E-52 T 29-03-2018 SMALA_RS37825 a6828bb1e2f7166e9addb0d26992ce3c 3375 SUPERFAMILY SSF55048 2423 2487 1.57E-13 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS37825 a6828bb1e2f7166e9addb0d26992ce3c 3375 Pfam PF08659 KR domain 2937 3114 3.0E-59 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37825 a6828bb1e2f7166e9addb0d26992ce3c 3375 Pfam PF08659 KR domain 1375 1554 2.7E-55 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37825 a6828bb1e2f7166e9addb0d26992ce3c 3375 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 411 528 5.4E-16 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37825 a6828bb1e2f7166e9addb0d26992ce3c 3375 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2136 2256 1.5E-12 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37825 a6828bb1e2f7166e9addb0d26992ce3c 3375 SMART SM01294 1662 1729 1.1E-4 T 29-03-2018 SMALA_RS37825 a6828bb1e2f7166e9addb0d26992ce3c 3375 SMART SM01294 3225 3292 3.1E-6 T 29-03-2018 SMALA_RS37825 a6828bb1e2f7166e9addb0d26992ce3c 3375 Pfam PF00698 Acyl transferase domain 2295 2617 3.2E-62 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS37825 a6828bb1e2f7166e9addb0d26992ce3c 3375 Pfam PF00698 Acyl transferase domain 564 883 2.0E-88 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS37825 a6828bb1e2f7166e9addb0d26992ce3c 3375 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 195 211 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS37825 a6828bb1e2f7166e9addb0d26992ce3c 3375 Gene3D G3DSA:3.30.70.250 701 751 5.3E-20 T 29-03-2018 SMALA_RS37825 a6828bb1e2f7166e9addb0d26992ce3c 3375 Gene3D G3DSA:3.30.70.250 2438 2477 1.2E-20 T 29-03-2018 SMALA_RS37825 a6828bb1e2f7166e9addb0d26992ce3c 3375 SUPERFAMILY SSF52151 756 854 8.37E-68 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS37825 a6828bb1e2f7166e9addb0d26992ce3c 3375 SUPERFAMILY SSF52151 563 691 8.37E-68 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS37825 a6828bb1e2f7166e9addb0d26992ce3c 3375 Gene3D G3DSA:3.40.366.10 2293 2437 1.5E-49 T 29-03-2018 SMALA_RS37825 a6828bb1e2f7166e9addb0d26992ce3c 3375 Gene3D G3DSA:3.40.366.10 563 700 7.3E-40 T 29-03-2018 SMALA_RS37825 a6828bb1e2f7166e9addb0d26992ce3c 3375 Gene3D G3DSA:1.10.1200.10 1653 1756 4.1E-19 T 29-03-2018 SMALA_RS37825 a6828bb1e2f7166e9addb0d26992ce3c 3375 SUPERFAMILY SSF52151 2488 2582 5.75E-75 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS37825 a6828bb1e2f7166e9addb0d26992ce3c 3375 SUPERFAMILY SSF52151 2294 2424 5.75E-75 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS37825 a6828bb1e2f7166e9addb0d26992ce3c 3375 Gene3D G3DSA:3.40.47.10 25 294 3.1E-85 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS37825 a6828bb1e2f7166e9addb0d26992ce3c 3375 Gene3D G3DSA:3.40.47.10 1757 2020 1.5E-86 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS37825 a6828bb1e2f7166e9addb0d26992ce3c 3375 SUPERFAMILY SSF51735 2933 3151 2.52E-49 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS37825 a6828bb1e2f7166e9addb0d26992ce3c 3375 SUPERFAMILY SSF47336 1657 1773 1.16E-21 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS37825 a6828bb1e2f7166e9addb0d26992ce3c 3375 SMART SM00825 Beta-ketoacyl synthase 35 461 3.1E-223 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS37825 a6828bb1e2f7166e9addb0d26992ce3c 3375 SMART SM00825 Beta-ketoacyl synthase 1760 2186 8.1E-220 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS37825 a6828bb1e2f7166e9addb0d26992ce3c 3375 SUPERFAMILY SSF51735 2714 2923 1.3E-47 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS37825 a6828bb1e2f7166e9addb0d26992ce3c 3375 SMART SM00826 931 1096 1.1E-81 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS37825 a6828bb1e2f7166e9addb0d26992ce3c 3375 SUPERFAMILY SSF47336 3218 3300 3.14E-19 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS37825 a6828bb1e2f7166e9addb0d26992ce3c 3375 Gene3D G3DSA:3.10.129.10 933 1060 6.7E-9 T 29-03-2018 SMALA_RS37825 a6828bb1e2f7166e9addb0d26992ce3c 3375 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1921 1937 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS37825 a6828bb1e2f7166e9addb0d26992ce3c 3375 SUPERFAMILY SSF53901 30 406 1.55E-101 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS37825 a6828bb1e2f7166e9addb0d26992ce3c 3375 SUPERFAMILY SSF53901 1756 2130 4.26E-105 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS39505 b490f9a19013b83d8095f33935dd7138 353 Gene3D G3DSA:1.10.3470.10 23 353 9.0E-61 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SMALA_RS39505 b490f9a19013b83d8095f33935dd7138 353 SUPERFAMILY SSF81345 20 349 9.68E-69 T 29-03-2018 IPR029022 ABC transporter, BtuC-like SMALA_RS39505 b490f9a19013b83d8095f33935dd7138 353 Pfam PF01032 FecCD transport family 39 349 1.4E-82 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 SMALA_RS26005 fcbc530e46cd1ef0bf1eb15414c64050 468 Pfam PF07687 Peptidase dimerisation domain 204 363 1.0E-22 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain SMALA_RS26005 fcbc530e46cd1ef0bf1eb15414c64050 468 Pfam PF01546 Peptidase family M20/M25/M40 90 459 6.0E-31 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 SMALA_RS26005 fcbc530e46cd1ef0bf1eb15414c64050 468 SUPERFAMILY SSF53187 378 463 6.86E-62 T 29-03-2018 SMALA_RS26005 fcbc530e46cd1ef0bf1eb15414c64050 468 SUPERFAMILY SSF53187 10 207 6.86E-62 T 29-03-2018 SMALA_RS26005 fcbc530e46cd1ef0bf1eb15414c64050 468 Gene3D G3DSA:3.30.70.360 211 373 2.1E-50 T 29-03-2018 SMALA_RS26005 fcbc530e46cd1ef0bf1eb15414c64050 468 Gene3D G3DSA:3.40.630.10 11 210 9.6E-37 T 29-03-2018 SMALA_RS34400 e3a43e93eebc97eaa68d390ebaadf869 150 Gene3D G3DSA:3.10.129.10 1 150 3.4E-18 T 29-03-2018 SMALA_RS34400 e3a43e93eebc97eaa68d390ebaadf869 150 SUPERFAMILY SSF54637 1 148 2.17E-19 T 29-03-2018 IPR029069 HotDog domain SMALA_RS34400 e3a43e93eebc97eaa68d390ebaadf869 150 Pfam PF14539 Domain of unknown function (DUF4442) 11 145 2.8E-26 T 29-03-2018 IPR027961 Protein of unknown function DUF4442 SMALA_RS26500 0a2e20d48c2c18e5d62e520cfb095878 361 Gene3D G3DSA:1.10.10.10 2 128 1.0E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS26500 0a2e20d48c2c18e5d62e520cfb095878 361 Gene3D G3DSA:1.10.132.20 157 230 0.0025 T 29-03-2018 SMALA_RS26500 0a2e20d48c2c18e5d62e520cfb095878 361 SUPERFAMILY SSF46785 10 122 3.81E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS26500 0a2e20d48c2c18e5d62e520cfb095878 361 Gene3D G3DSA:1.10.10.10 271 361 0.024 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS26500 0a2e20d48c2c18e5d62e520cfb095878 361 Pfam PF03551 Transcriptional regulator PadR-like family 14 82 9.2E-22 T 29-03-2018 IPR005149 Transcription regulator PadR, N-terminal SMALA_RS22580 3c240c5443cca2f2cb197cbd15e1a21b 95 ProSitePatterns PS00056 Ribosomal protein S17 signature. 68 80 - T 29-03-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMALA_RS22580 3c240c5443cca2f2cb197cbd15e1a21b 95 Pfam PF00366 Ribosomal protein S17 22 89 1.8E-30 T 29-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS22580 3c240c5443cca2f2cb197cbd15e1a21b 95 SUPERFAMILY SSF50249 17 94 2.14E-30 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMALA_RS22580 3c240c5443cca2f2cb197cbd15e1a21b 95 Gene3D G3DSA:2.40.50.140 17 94 8.1E-29 T 29-03-2018 SMALA_RS22580 3c240c5443cca2f2cb197cbd15e1a21b 95 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 17 92 24.955 T 29-03-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS22580 3c240c5443cca2f2cb197cbd15e1a21b 95 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 17 88 1.1E-34 T 29-03-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS22580 3c240c5443cca2f2cb197cbd15e1a21b 95 PRINTS PR00973 Ribosomal protein S17 family signature 78 85 1.4E-11 T 29-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS22580 3c240c5443cca2f2cb197cbd15e1a21b 95 PRINTS PR00973 Ribosomal protein S17 family signature 36 59 1.4E-11 T 29-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS22580 3c240c5443cca2f2cb197cbd15e1a21b 95 PRINTS PR00973 Ribosomal protein S17 family signature 68 78 1.4E-11 T 29-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS22580 3c240c5443cca2f2cb197cbd15e1a21b 95 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 22 88 2.0E-32 T 29-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS04765 9af0474e3244383885772b2b5c90da48 772 SUPERFAMILY SSF51726 12 403 1.28E-99 T 29-03-2018 SMALA_RS04765 9af0474e3244383885772b2b5c90da48 772 Gene3D G3DSA:3.20.20.210 400 769 5.7E-121 T 29-03-2018 SMALA_RS04765 9af0474e3244383885772b2b5c90da48 772 Pfam PF08267 Cobalamin-independent synthase, N-terminal domain 13 323 6.8E-113 T 29-03-2018 IPR013215 Cobalamin-independent methionine synthase MetE, N-terminal GO:0003871|GO:0008270|GO:0008652 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 SMALA_RS04765 9af0474e3244383885772b2b5c90da48 772 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 441 763 1.9E-142 T 29-03-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 SMALA_RS04765 9af0474e3244383885772b2b5c90da48 772 PIRSF PIRSF000382 9 772 0.0 T 29-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 SMALA_RS04765 9af0474e3244383885772b2b5c90da48 772 Hamap MF_00172 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [metE]. 10 768 34.947 T 29-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 SMALA_RS04765 9af0474e3244383885772b2b5c90da48 772 SUPERFAMILY SSF51726 406 767 2.49E-110 T 29-03-2018 SMALA_RS04765 9af0474e3244383885772b2b5c90da48 772 TIGRFAM TIGR01371 met_syn_B12ind: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase 16 767 0.0 T 29-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 SMALA_RS04765 9af0474e3244383885772b2b5c90da48 772 Gene3D G3DSA:3.20.20.210 10 399 1.2E-133 T 29-03-2018 SMALA_RS21980 bedae3a9bba634d8e3cf41b6b3124e55 483 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 11 423 1.4E-157 T 29-03-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 SMALA_RS21980 bedae3a9bba634d8e3cf41b6b3124e55 483 TIGRFAM TIGR03701 mena_SCO4490: menaquinone biosynthesis decarboxylase, SCO4490 family 8 440 7.4E-196 T 29-03-2018 IPR022390 4-hydroxybenzoate decarboxylase subunit C GO:0016831 SMALA_RS21980 bedae3a9bba634d8e3cf41b6b3124e55 483 SUPERFAMILY SSF143968 318 483 1.7E-54 T 29-03-2018 SMALA_RS21980 bedae3a9bba634d8e3cf41b6b3124e55 483 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 6 448 3.9E-137 T 29-03-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 SMALA_RS21980 bedae3a9bba634d8e3cf41b6b3124e55 483 Gene3D G3DSA:3.40.1670.10 318 453 9.1E-41 T 29-03-2018 SMALA_RS21980 bedae3a9bba634d8e3cf41b6b3124e55 483 SUPERFAMILY SSF50475 3 317 1.33E-113 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS21980 bedae3a9bba634d8e3cf41b6b3124e55 483 Gene3D G3DSA:1.20.5.570 454 483 1.3E-9 T 29-03-2018 SMALA_RS00110 bedae3a9bba634d8e3cf41b6b3124e55 483 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 11 423 1.4E-157 T 29-03-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 SMALA_RS00110 bedae3a9bba634d8e3cf41b6b3124e55 483 TIGRFAM TIGR03701 mena_SCO4490: menaquinone biosynthesis decarboxylase, SCO4490 family 8 440 7.4E-196 T 29-03-2018 IPR022390 4-hydroxybenzoate decarboxylase subunit C GO:0016831 SMALA_RS00110 bedae3a9bba634d8e3cf41b6b3124e55 483 SUPERFAMILY SSF143968 318 483 1.7E-54 T 29-03-2018 SMALA_RS00110 bedae3a9bba634d8e3cf41b6b3124e55 483 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 6 448 3.9E-137 T 29-03-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 SMALA_RS00110 bedae3a9bba634d8e3cf41b6b3124e55 483 Gene3D G3DSA:3.40.1670.10 318 453 9.1E-41 T 29-03-2018 SMALA_RS00110 bedae3a9bba634d8e3cf41b6b3124e55 483 SUPERFAMILY SSF50475 3 317 1.33E-113 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS00110 bedae3a9bba634d8e3cf41b6b3124e55 483 Gene3D G3DSA:1.20.5.570 454 483 1.3E-9 T 29-03-2018 SMALA_RS28340 b281a95308bcf4b880d25347b236b135 415 Pfam PF13416 Bacterial extracellular solute-binding protein 99 378 3.2E-27 T 29-03-2018 SMALA_RS28340 b281a95308bcf4b880d25347b236b135 415 SUPERFAMILY SSF53850 75 411 9.39E-58 T 29-03-2018 SMALA_RS28340 b281a95308bcf4b880d25347b236b135 415 Gene3D G3DSA:3.40.190.10 206 363 2.8E-30 T 29-03-2018 SMALA_RS28340 b281a95308bcf4b880d25347b236b135 415 Gene3D G3DSA:3.40.190.10 68 205 8.8E-14 T 29-03-2018 SMALA_RS07330 4bcfe99b1bef6460d33610ed9d0a7871 536 Gene3D G3DSA:3.50.50.60 7 231 3.2E-21 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS07330 4bcfe99b1bef6460d33610ed9d0a7871 536 Gene3D G3DSA:3.30.9.10 232 355 5.3E-33 T 29-03-2018 SMALA_RS07330 4bcfe99b1bef6460d33610ed9d0a7871 536 Pfam PF01266 FAD dependent oxidoreductase 35 389 6.0E-50 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 SMALA_RS07330 4bcfe99b1bef6460d33610ed9d0a7871 536 SUPERFAMILY SSF51905 33 285 3.7E-35 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS07330 4bcfe99b1bef6460d33610ed9d0a7871 536 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 34 46 2.1E-19 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 SMALA_RS07330 4bcfe99b1bef6460d33610ed9d0a7871 536 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 349 355 2.1E-19 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 SMALA_RS07330 4bcfe99b1bef6460d33610ed9d0a7871 536 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 109 121 2.1E-19 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 SMALA_RS07330 4bcfe99b1bef6460d33610ed9d0a7871 536 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 63 75 2.1E-19 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 SMALA_RS07330 4bcfe99b1bef6460d33610ed9d0a7871 536 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 378 390 2.1E-19 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 SMALA_RS07330 4bcfe99b1bef6460d33610ed9d0a7871 536 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 447 534 1.2E-17 T 29-03-2018 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 SMALA_RS36780 332b5c494a30d53750a27f5bcb89cec4 465 Gene3D G3DSA:3.40.630.10 3 447 8.5E-25 T 29-03-2018 SMALA_RS36780 332b5c494a30d53750a27f5bcb89cec4 465 Pfam PF04389 Peptidase family M28 241 432 5.4E-10 T 29-03-2018 IPR007484 Peptidase M28 SMALA_RS36780 332b5c494a30d53750a27f5bcb89cec4 465 SUPERFAMILY SSF53187 233 445 8.25E-24 T 29-03-2018 SMALA_RS36780 332b5c494a30d53750a27f5bcb89cec4 465 SUPERFAMILY SSF53187 5 67 8.25E-24 T 29-03-2018 SMALA_RS12875 2066e71fa89524dad8e7be4e175fc491 597 Gene3D G3DSA:3.20.20.70 39 417 1.1E-111 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS12875 2066e71fa89524dad8e7be4e175fc491 597 Hamap MF_00572 2-isopropylmalate synthase [leuA]. 37 597 54.286 T 29-03-2018 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 SMALA_RS12875 2066e71fa89524dad8e7be4e175fc491 597 SMART SM00917 463 596 1.2E-37 T 29-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 SMALA_RS12875 2066e71fa89524dad8e7be4e175fc491 597 SUPERFAMILY SSF51569 51 361 2.2E-95 T 29-03-2018 SMALA_RS12875 2066e71fa89524dad8e7be4e175fc491 597 SUPERFAMILY SSF89000 429 478 3.14E-15 T 29-03-2018 SMALA_RS12875 2066e71fa89524dad8e7be4e175fc491 597 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 274 287 - T 29-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 SMALA_RS12875 2066e71fa89524dad8e7be4e175fc491 597 Pfam PF00682 HMGL-like 62 342 3.9E-74 T 29-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 SMALA_RS12875 2066e71fa89524dad8e7be4e175fc491 597 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 69 85 - T 29-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 SMALA_RS12875 2066e71fa89524dad8e7be4e175fc491 597 TIGRFAM TIGR00970 leuA_yeast: 2-isopropylmalate synthase 36 597 2.5E-253 T 29-03-2018 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 SMALA_RS12875 2066e71fa89524dad8e7be4e175fc491 597 Pfam PF08502 LeuA allosteric (dimerisation) domain 463 595 3.2E-33 T 29-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 SMALA_RS12875 2066e71fa89524dad8e7be4e175fc491 597 SUPERFAMILY SSF110921 493 595 8.89E-35 T 29-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 SMALA_RS31750 9322b42d9face29eeafb2acbc1e2b142 829 Gene3D G3DSA:3.40.50.620 209 354 2.9E-13 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS31750 9322b42d9face29eeafb2acbc1e2b142 829 Pfam PF13493 Domain of unknown function (DUF4118) 386 488 7.8E-21 T 29-03-2018 IPR025201 Sensor protein KdpD, transmembrane domain SMALA_RS31750 9322b42d9face29eeafb2acbc1e2b142 829 Pfam PF02702 Osmosensitive K+ channel His kinase sensor domain 3 211 7.8E-96 T 29-03-2018 IPR003852 Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal GO:0000155|GO:0000160|GO:0004673|GO:0016020 SMALA_RS31750 9322b42d9face29eeafb2acbc1e2b142 829 Gene3D G3DSA:3.40.50.300 2 138 4.1E-22 T 29-03-2018 SMALA_RS31750 9322b42d9face29eeafb2acbc1e2b142 829 Gene3D G3DSA:1.20.120.620 382 481 1.8E-18 T 29-03-2018 SMALA_RS31750 9322b42d9face29eeafb2acbc1e2b142 829 Gene3D G3DSA:3.30.565.10 682 822 3.2E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS31750 9322b42d9face29eeafb2acbc1e2b142 829 SUPERFAMILY SSF55874 669 817 4.4E-12 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS31750 9322b42d9face29eeafb2acbc1e2b142 829 SUPERFAMILY SSF47384 607 679 4.71E-6 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS31750 9322b42d9face29eeafb2acbc1e2b142 829 Pfam PF00582 Universal stress protein family 231 354 1.6E-8 T 29-03-2018 IPR006016 UspA GO:0006950 SMALA_RS31750 9322b42d9face29eeafb2acbc1e2b142 829 Gene3D G3DSA:1.10.287.130 607 675 2.6E-5 T 29-03-2018 SMALA_RS31750 9322b42d9face29eeafb2acbc1e2b142 829 SUPERFAMILY SSF52402 232 354 3.56E-9 T 29-03-2018 SMALA_RS35860 5759aa260b4f08cfca1ef76b3a09fc1e 279 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 164 192 - T 29-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 SMALA_RS35860 5759aa260b4f08cfca1ef76b3a09fc1e 279 SUPERFAMILY SSF51161 57 212 4.6E-34 T 29-03-2018 IPR011004 Trimeric LpxA-like SMALA_RS35860 5759aa260b4f08cfca1ef76b3a09fc1e 279 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 156 190 1.9E-9 T 29-03-2018 IPR001451 Hexapeptide repeat SMALA_RS35860 5759aa260b4f08cfca1ef76b3a09fc1e 279 Gene3D G3DSA:2.160.10.10 93 216 2.4E-30 T 29-03-2018 SMALA_RS35860 5759aa260b4f08cfca1ef76b3a09fc1e 279 Gene3D G3DSA:2.160.10.10 44 92 0.13 T 29-03-2018 SMALA_RS32910 a97b82beb3da314f7eed2a13f530b467 207 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 3 152 5.6E-53 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 SMALA_RS32910 a97b82beb3da314f7eed2a13f530b467 207 ProSitePatterns PS01321 Crossover junction endodeoxyribonuclease ruvC signature. 114 149 - T 29-03-2018 IPR020563 Crossover junction endodeoxyribonuclease RuvC, magnesium-binding site GO:0008821 SMALA_RS32910 a97b82beb3da314f7eed2a13f530b467 207 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 108 127 1.1E-35 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 SMALA_RS32910 a97b82beb3da314f7eed2a13f530b467 207 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 140 152 1.1E-35 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 SMALA_RS32910 a97b82beb3da314f7eed2a13f530b467 207 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 4 17 1.1E-35 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 SMALA_RS32910 a97b82beb3da314f7eed2a13f530b467 207 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 62 78 1.1E-35 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 SMALA_RS32910 a97b82beb3da314f7eed2a13f530b467 207 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 84 100 1.1E-35 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 SMALA_RS32910 a97b82beb3da314f7eed2a13f530b467 207 SUPERFAMILY SSF53098 2 156 3.53E-44 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SMALA_RS32910 a97b82beb3da314f7eed2a13f530b467 207 TIGRFAM TIGR00228 ruvC: crossover junction endodeoxyribonuclease RuvC 3 155 2.3E-34 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 SMALA_RS32910 a97b82beb3da314f7eed2a13f530b467 207 Gene3D G3DSA:3.30.420.10 1 160 1.4E-46 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SMALA_RS32910 a97b82beb3da314f7eed2a13f530b467 207 Hamap MF_00034 Crossover junction endodeoxyribonuclease RuvC [ruvC]. 1 155 44.909 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 SMALA_RS12745 a04513da11afc2455ee23c0b6b4a5be7 191 Gene3D G3DSA:1.10.3300.10 6 185 2.5E-39 T 29-03-2018 IPR023286 ABATE domain SMALA_RS12745 a04513da11afc2455ee23c0b6b4a5be7 191 SUPERFAMILY SSF160904 7 181 6.41E-40 T 29-03-2018 SMALA_RS12745 a04513da11afc2455ee23c0b6b4a5be7 191 Pfam PF11706 CGNR zinc finger 141 181 4.8E-15 T 29-03-2018 IPR021005 Zinc finger, CGNR SMALA_RS12745 a04513da11afc2455ee23c0b6b4a5be7 191 Pfam PF07336 Putative stress-induced transcription regulator 14 135 9.9E-20 T 29-03-2018 IPR010852 Putative stress-induced transcription regulator SMALA_RS43250 402a1f42087fe17fe56369070b29ed19 140 Gene3D G3DSA:3.40.50.1010 1 137 2.3E-16 T 29-03-2018 IPR029060 PIN domain-like SMALA_RS43250 402a1f42087fe17fe56369070b29ed19 140 Pfam PF01850 PIN domain 2 123 5.0E-11 T 29-03-2018 IPR002716 PIN domain SMALA_RS43250 402a1f42087fe17fe56369070b29ed19 140 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 134 11.32 T 29-03-2018 IPR022907 VapC family GO:0004540 SMALA_RS43250 402a1f42087fe17fe56369070b29ed19 140 SUPERFAMILY SSF88723 2 130 1.44E-18 T 29-03-2018 IPR029060 PIN domain-like SMALA_RS08240 98564a371f63922c588067541a867bbe 260 Gene3D G3DSA:3.30.470.10 4 100 3.5E-14 T 29-03-2018 SMALA_RS08240 98564a371f63922c588067541a867bbe 260 Gene3D G3DSA:3.20.10.10 110 257 5.6E-30 T 29-03-2018 SMALA_RS08240 98564a371f63922c588067541a867bbe 260 Pfam PF01063 Amino-transferase class IV 23 233 1.2E-32 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 SMALA_RS08240 98564a371f63922c588067541a867bbe 260 SUPERFAMILY SSF56752 11 240 4.06E-42 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 SMALA_RS09845 b11ed6ca77987be55ba3e84aa18d6a4f 476 Pfam PF02887 Pyruvate kinase, alpha/beta domain 356 468 1.3E-27 T 29-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMALA_RS09845 b11ed6ca77987be55ba3e84aa18d6a4f 476 Gene3D G3DSA:3.40.1380.20 319 471 3.9E-45 T 29-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMALA_RS09845 b11ed6ca77987be55ba3e84aa18d6a4f 476 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 2 470 1.6E-163 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMALA_RS09845 b11ed6ca77987be55ba3e84aa18d6a4f 476 ProSitePatterns PS00110 Pyruvate kinase active site signature. 212 224 - T 29-03-2018 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMALA_RS09845 b11ed6ca77987be55ba3e84aa18d6a4f 476 PRINTS PR01050 Pyruvate kinase family signature 291 309 7.1E-65 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMALA_RS09845 b11ed6ca77987be55ba3e84aa18d6a4f 476 PRINTS PR01050 Pyruvate kinase family signature 59 75 7.1E-65 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMALA_RS09845 b11ed6ca77987be55ba3e84aa18d6a4f 476 PRINTS PR01050 Pyruvate kinase family signature 184 198 7.1E-65 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMALA_RS09845 b11ed6ca77987be55ba3e84aa18d6a4f 476 PRINTS PR01050 Pyruvate kinase family signature 241 265 7.1E-65 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMALA_RS09845 b11ed6ca77987be55ba3e84aa18d6a4f 476 PRINTS PR01050 Pyruvate kinase family signature 266 290 7.1E-65 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMALA_RS09845 b11ed6ca77987be55ba3e84aa18d6a4f 476 PRINTS PR01050 Pyruvate kinase family signature 310 326 7.1E-65 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMALA_RS09845 b11ed6ca77987be55ba3e84aa18d6a4f 476 PRINTS PR01050 Pyruvate kinase family signature 214 240 7.1E-65 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMALA_RS09845 b11ed6ca77987be55ba3e84aa18d6a4f 476 SUPERFAMILY SSF52935 321 471 1.83E-37 T 29-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMALA_RS09845 b11ed6ca77987be55ba3e84aa18d6a4f 476 SUPERFAMILY SSF51621 1 74 1.08E-97 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SMALA_RS09845 b11ed6ca77987be55ba3e84aa18d6a4f 476 SUPERFAMILY SSF51621 154 337 1.08E-97 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SMALA_RS09845 b11ed6ca77987be55ba3e84aa18d6a4f 476 Pfam PF00224 Pyruvate kinase, barrel domain 1 336 4.3E-121 T 29-03-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMALA_RS09845 b11ed6ca77987be55ba3e84aa18d6a4f 476 Gene3D G3DSA:3.20.20.60 1 81 1.4E-17 T 29-03-2018 SMALA_RS09845 b11ed6ca77987be55ba3e84aa18d6a4f 476 Gene3D G3DSA:2.40.33.10 82 157 8.4E-25 T 29-03-2018 SMALA_RS09845 b11ed6ca77987be55ba3e84aa18d6a4f 476 SUPERFAMILY SSF50800 70 164 9.59E-26 T 29-03-2018 IPR011037 Pyruvate kinase-like, insert domain SMALA_RS09845 b11ed6ca77987be55ba3e84aa18d6a4f 476 Gene3D G3DSA:3.20.20.60 158 318 5.5E-61 T 29-03-2018 SMALA_RS27390 65a739de555cceaaa18b6dcb8b35a94f 742 SUPERFAMILY SSF49313 542 625 9.42E-12 T 29-03-2018 IPR015919 Cadherin-like GO:0005509|GO:0016020 SMALA_RS27390 65a739de555cceaaa18b6dcb8b35a94f 742 Gene3D G3DSA:2.60.40.10 537 624 1.0E-14 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS27390 65a739de555cceaaa18b6dcb8b35a94f 742 SUPERFAMILY SSF49785 639 742 1.57E-24 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS27390 65a739de555cceaaa18b6dcb8b35a94f 742 Gene3D G3DSA:2.60.120.260 625 742 1.6E-27 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS27390 65a739de555cceaaa18b6dcb8b35a94f 742 Gene3D G3DSA:1.10.390.10 362 536 7.5E-49 T 29-03-2018 SMALA_RS27390 65a739de555cceaaa18b6dcb8b35a94f 742 Pfam PF01483 Proprotein convertase P-domain 662 742 1.6E-19 T 29-03-2018 IPR002884 Proprotein convertase, P GO:0004252|GO:0006508 SMALA_RS27390 65a739de555cceaaa18b6dcb8b35a94f 742 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 360 534 3.3E-51 T 29-03-2018 IPR001570 Peptidase M4, C-terminal GO:0004222 SMALA_RS27390 65a739de555cceaaa18b6dcb8b35a94f 742 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 210 357 7.4E-47 T 29-03-2018 IPR013856 Peptidase M4 domain GO:0004222 SMALA_RS27390 65a739de555cceaaa18b6dcb8b35a94f 742 Gene3D G3DSA:3.10.170.10 207 361 1.0E-44 T 29-03-2018 SMALA_RS27390 65a739de555cceaaa18b6dcb8b35a94f 742 SUPERFAMILY SSF55486 209 535 9.34E-77 T 29-03-2018 SMALA_RS27390 65a739de555cceaaa18b6dcb8b35a94f 742 Pfam PF05345 Putative Ig domain 575 613 1.5E-10 T 29-03-2018 IPR008009 Putative Ig SMALA_RS27390 65a739de555cceaaa18b6dcb8b35a94f 742 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 369 380 1.3E-16 T 29-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 SMALA_RS27390 65a739de555cceaaa18b6dcb8b35a94f 742 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 436 452 1.3E-16 T 29-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 SMALA_RS27390 65a739de555cceaaa18b6dcb8b35a94f 742 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 312 332 1.3E-16 T 29-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 SMALA_RS27390 65a739de555cceaaa18b6dcb8b35a94f 742 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 348 364 1.3E-16 T 29-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 SMALA_RS27390 65a739de555cceaaa18b6dcb8b35a94f 742 Pfam PF07504 Fungalysin/Thermolysin Propeptide Motif 70 115 1.1E-14 T 29-03-2018 IPR011096 FTP domain SMALA_RS04515 c9e27626f182411f6d4e4779c402091a 139 PIRSF PIRSF004681 2 139 4.1E-28 T 29-03-2018 IPR001602 Uncharacterised protein family UPF0047 SMALA_RS04515 c9e27626f182411f6d4e4779c402091a 139 Gene3D G3DSA:2.60.120.460 1 139 4.9E-32 T 29-03-2018 IPR001602 Uncharacterised protein family UPF0047 SMALA_RS04515 c9e27626f182411f6d4e4779c402091a 139 Pfam PF01894 Uncharacterised protein family UPF0047 21 135 3.3E-23 T 29-03-2018 IPR001602 Uncharacterised protein family UPF0047 SMALA_RS04515 c9e27626f182411f6d4e4779c402091a 139 SUPERFAMILY SSF111038 5 139 4.58E-33 T 29-03-2018 IPR001602 Uncharacterised protein family UPF0047 SMALA_RS41635 87cb01d3174e3ef905129d5c50550a9d 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMALA_RS41635 87cb01d3174e3ef905129d5c50550a9d 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 6.0E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS41635 87cb01d3174e3ef905129d5c50550a9d 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 6.0E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS41635 87cb01d3174e3ef905129d5c50550a9d 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 6.0E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS41635 87cb01d3174e3ef905129d5c50550a9d 253 Gene3D G3DSA:3.40.50.720 1 42 7.4E-6 T 29-03-2018 SMALA_RS41635 87cb01d3174e3ef905129d5c50550a9d 253 Gene3D G3DSA:3.40.50.720 43 252 1.0E-54 T 29-03-2018 SMALA_RS41635 87cb01d3174e3ef905129d5c50550a9d 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 249 1.0E-57 T 29-03-2018 SMALA_RS41635 87cb01d3174e3ef905129d5c50550a9d 253 SUPERFAMILY SSF51735 6 249 1.66E-70 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS41635 87cb01d3174e3ef905129d5c50550a9d 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 2.2E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS41635 87cb01d3174e3ef905129d5c50550a9d 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 2.2E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS41635 87cb01d3174e3ef905129d5c50550a9d 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 2.2E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS41635 87cb01d3174e3ef905129d5c50550a9d 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.2E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS41635 87cb01d3174e3ef905129d5c50550a9d 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 2.2E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS41635 87cb01d3174e3ef905129d5c50550a9d 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 2.2E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS39075 89fb48767635daa74348f17de49c8669 68 SUPERFAMILY SSF160582 2 67 1.96E-31 T 29-03-2018 SMALA_RS39075 89fb48767635daa74348f17de49c8669 68 Pfam PF03621 MbtH-like protein 2 52 4.0E-28 T 29-03-2018 IPR005153 MbtH-like protein SMALA_RS39075 89fb48767635daa74348f17de49c8669 68 Gene3D G3DSA:3.90.820.10 1 67 1.7E-36 T 29-03-2018 SMALA_RS39075 89fb48767635daa74348f17de49c8669 68 SMART SM00923 2 52 4.0E-31 T 29-03-2018 IPR005153 MbtH-like protein SMALA_RS40805 747f94613d6b67abbb085365c1ac1830 240 Gene3D G3DSA:1.10.10.10 2 69 7.0E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS40805 747f94613d6b67abbb085365c1ac1830 240 SUPERFAMILY SSF46785 4 71 6.56E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS40805 747f94613d6b67abbb085365c1ac1830 240 Pfam PF07729 FCD domain 92 214 2.5E-21 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS40805 747f94613d6b67abbb085365c1ac1830 240 SUPERFAMILY SSF48008 91 217 2.62E-21 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS40805 747f94613d6b67abbb085365c1ac1830 240 SMART SM00345 8 67 1.1E-18 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS40805 747f94613d6b67abbb085365c1ac1830 240 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 27 41 8.9E-8 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS40805 747f94613d6b67abbb085365c1ac1830 240 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 41 57 8.9E-8 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS40805 747f94613d6b67abbb085365c1ac1830 240 SMART SM00895 92 215 4.8E-19 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS40805 747f94613d6b67abbb085365c1ac1830 240 Gene3D G3DSA:1.20.120.530 72 219 7.3E-24 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS40805 747f94613d6b67abbb085365c1ac1830 240 Pfam PF00392 Bacterial regulatory proteins, gntR family 4 67 3.4E-21 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS29700 f91a73fa01d0212988320f12e92a21ae 714 SUPERFAMILY SSF51011 351 437 7.29E-16 T 29-03-2018 SMALA_RS29700 f91a73fa01d0212988320f12e92a21ae 714 Gene3D G3DSA:3.20.20.70 48 350 7.7E-70 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS29700 f91a73fa01d0212988320f12e92a21ae 714 Gene3D G3DSA:2.60.40.1180 352 438 1.5E-18 T 29-03-2018 SMALA_RS29700 f91a73fa01d0212988320f12e92a21ae 714 PRINTS PR00740 Glycosyl hydrolase family 27 signature 129 150 4.2E-22 T 29-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 SMALA_RS29700 f91a73fa01d0212988320f12e92a21ae 714 PRINTS PR00740 Glycosyl hydrolase family 27 signature 87 102 4.2E-22 T 29-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 SMALA_RS29700 f91a73fa01d0212988320f12e92a21ae 714 PRINTS PR00740 Glycosyl hydrolase family 27 signature 194 212 4.2E-22 T 29-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 SMALA_RS29700 f91a73fa01d0212988320f12e92a21ae 714 PRINTS PR00740 Glycosyl hydrolase family 27 signature 165 182 4.2E-22 T 29-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 SMALA_RS29700 f91a73fa01d0212988320f12e92a21ae 714 PRINTS PR00740 Glycosyl hydrolase family 27 signature 52 71 4.2E-22 T 29-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 SMALA_RS29700 f91a73fa01d0212988320f12e92a21ae 714 PRINTS PR00740 Glycosyl hydrolase family 27 signature 305 326 4.2E-22 T 29-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 SMALA_RS29700 f91a73fa01d0212988320f12e92a21ae 714 Gene3D G3DSA:2.120.10.70 439 568 7.9E-15 T 29-03-2018 SMALA_RS29700 f91a73fa01d0212988320f12e92a21ae 714 Gene3D G3DSA:2.120.10.70 677 714 0.048 T 29-03-2018 SMALA_RS29700 f91a73fa01d0212988320f12e92a21ae 714 Gene3D G3DSA:2.120.10.70 569 676 1.2E-16 T 29-03-2018 SMALA_RS29700 f91a73fa01d0212988320f12e92a21ae 714 Pfam PF16499 Alpha galactosidase A 73 349 1.4E-41 T 29-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 SMALA_RS29700 f91a73fa01d0212988320f12e92a21ae 714 SUPERFAMILY SSF51445 51 350 4.21E-58 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS29700 f91a73fa01d0212988320f12e92a21ae 714 SUPERFAMILY SSF89372 450 712 4.05E-30 T 29-03-2018 SMALA_RS27655 09dc7fabd9a7db79ca8890970c381bc8 98 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 4 95 8.2E-25 T 29-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 SMALA_RS27655 09dc7fabd9a7db79ca8890970c381bc8 98 SUPERFAMILY SSF141000 4 94 6.15E-27 T 29-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 SMALA_RS27655 09dc7fabd9a7db79ca8890970c381bc8 98 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 21 91 5.3E-16 T 29-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 SMALA_RS27655 09dc7fabd9a7db79ca8890970c381bc8 98 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 3 96 23.409 T 29-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 SMALA_RS11685 8a3b6387f7487c2a00bc07df45c74f81 233 SUPERFAMILY SSF53955 44 178 2.01E-27 T 29-03-2018 IPR023346 Lysozyme-like domain SMALA_RS11685 8a3b6387f7487c2a00bc07df45c74f81 233 Pfam PF01464 Transglycosylase SLT domain 61 172 3.8E-12 T 29-03-2018 IPR008258 Transglycosylase SLT domain 1 SMALA_RS11685 8a3b6387f7487c2a00bc07df45c74f81 233 Gene3D G3DSA:1.10.530.10 41 193 3.2E-32 T 29-03-2018 SMALA_RS36460 7df5437fdfa45b916f98b7085f8597bc 310 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 178 299 4.7E-25 T 29-03-2018 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 SMALA_RS36460 7df5437fdfa45b916f98b7085f8597bc 310 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 152 1.1E-38 T 29-03-2018 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 SMALA_RS36460 7df5437fdfa45b916f98b7085f8597bc 310 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 2 298 1.0E-68 T 29-03-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0015940|GO:0016491|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 SMALA_RS36460 7df5437fdfa45b916f98b7085f8597bc 310 Gene3D G3DSA:3.40.50.720 1 177 5.4E-38 T 29-03-2018 SMALA_RS36460 7df5437fdfa45b916f98b7085f8597bc 310 SUPERFAMILY SSF51735 1 130 1.74E-17 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS36460 7df5437fdfa45b916f98b7085f8597bc 310 SUPERFAMILY SSF48179 178 299 2.86E-25 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMALA_RS36460 7df5437fdfa45b916f98b7085f8597bc 310 Gene3D G3DSA:1.10.1040.10 178 305 3.2E-26 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMALA_RS23390 95228be6fe62e9855b6f7ce98a47fd6c 415 Gene3D G3DSA:3.20.20.80 92 406 2.8E-4 T 29-03-2018 SMALA_RS34780 7cc8b642a8bb2d787f9b94cb9871ba4f 211 PRINTS PR00127 Clp protease catalytic subunit P signature 96 113 1.6E-37 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMALA_RS34780 7cc8b642a8bb2d787f9b94cb9871ba4f 211 PRINTS PR00127 Clp protease catalytic subunit P signature 25 40 1.6E-37 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMALA_RS34780 7cc8b642a8bb2d787f9b94cb9871ba4f 211 PRINTS PR00127 Clp protease catalytic subunit P signature 176 195 1.6E-37 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMALA_RS34780 7cc8b642a8bb2d787f9b94cb9871ba4f 211 PRINTS PR00127 Clp protease catalytic subunit P signature 65 85 1.6E-37 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMALA_RS34780 7cc8b642a8bb2d787f9b94cb9871ba4f 211 PRINTS PR00127 Clp protease catalytic subunit P signature 117 136 1.6E-37 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMALA_RS34780 7cc8b642a8bb2d787f9b94cb9871ba4f 211 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 9 201 35.869 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMALA_RS34780 7cc8b642a8bb2d787f9b94cb9871ba4f 211 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 96 107 - T 29-03-2018 IPR018215 ClpP, Ser active site SMALA_RS34780 7cc8b642a8bb2d787f9b94cb9871ba4f 211 Gene3D G3DSA:3.90.226.10 8 202 8.5E-36 T 29-03-2018 SMALA_RS34780 7cc8b642a8bb2d787f9b94cb9871ba4f 211 SUPERFAMILY SSF52096 17 202 4.56E-55 T 29-03-2018 IPR029045 ClpP/crotonase-like domain SMALA_RS34780 7cc8b642a8bb2d787f9b94cb9871ba4f 211 Pfam PF00574 Clp protease 20 200 2.8E-67 T 29-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA SMALA_RS05555 f4c4d292f9e7089ecc415b2b463b34ac 237 SUPERFAMILY SSF46785 13 104 5.55E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS05555 f4c4d292f9e7089ecc415b2b463b34ac 237 SMART SM00895 89 214 3.4E-13 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS05555 f4c4d292f9e7089ecc415b2b463b34ac 237 Pfam PF00392 Bacterial regulatory proteins, gntR family 18 79 1.4E-14 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS05555 f4c4d292f9e7089ecc415b2b463b34ac 237 Pfam PF07729 FCD domain 89 210 5.4E-20 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS05555 f4c4d292f9e7089ecc415b2b463b34ac 237 SMART SM00345 21 79 4.2E-12 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS05555 f4c4d292f9e7089ecc415b2b463b34ac 237 Gene3D G3DSA:1.10.10.10 6 81 5.2E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS05555 f4c4d292f9e7089ecc415b2b463b34ac 237 SUPERFAMILY SSF48008 85 221 4.97E-24 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS05555 f4c4d292f9e7089ecc415b2b463b34ac 237 Gene3D G3DSA:1.20.120.530 82 231 3.8E-27 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS15125 199f556f0258caeee83bb1e64757ba7e 382 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 186 336 2.0E-18 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMALA_RS15125 199f556f0258caeee83bb1e64757ba7e 382 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 23 137 2.6E-4 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMALA_RS15125 199f556f0258caeee83bb1e64757ba7e 382 Gene3D G3DSA:3.10.180.10 7 181 1.0E-33 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS15125 199f556f0258caeee83bb1e64757ba7e 382 TIGRFAM TIGR01263 4HPPD: 4-hydroxyphenylpyruvate dioxygenase 23 382 3.2E-136 T 29-03-2018 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 SMALA_RS15125 199f556f0258caeee83bb1e64757ba7e 382 PIRSF PIRSF009283 9 382 1.1E-135 T 29-03-2018 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 SMALA_RS15125 199f556f0258caeee83bb1e64757ba7e 382 SUPERFAMILY SSF54593 16 369 3.49E-92 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS15125 199f556f0258caeee83bb1e64757ba7e 382 Gene3D G3DSA:3.10.180.10 182 382 2.7E-72 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS17725 610be72562b9f983e07ca3e5336a2603 204 Gene3D G3DSA:3.40.430.10 2 181 7.8E-36 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 SMALA_RS17725 610be72562b9f983e07ca3e5336a2603 204 Pfam PF01872 RibD C-terminal domain 2 177 2.5E-19 T 29-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 SMALA_RS17725 610be72562b9f983e07ca3e5336a2603 204 SUPERFAMILY SSF53597 2 183 6.15E-30 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 SMALA_RS08670 1b284a6746f91f34c07fbaa6267dbc5e 361 SUPERFAMILY SSF55021 294 355 1.17E-5 T 29-03-2018 SMALA_RS08670 1b284a6746f91f34c07fbaa6267dbc5e 361 Gene3D G3DSA:3.30.70.260 293 360 1.8E-5 T 29-03-2018 SMALA_RS08670 1b284a6746f91f34c07fbaa6267dbc5e 361 SUPERFAMILY SSF48179 166 251 3.17E-22 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMALA_RS08670 1b284a6746f91f34c07fbaa6267dbc5e 361 Pfam PF02153 Prephenate dehydrogenase 18 250 2.7E-58 T 29-03-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 SMALA_RS08670 1b284a6746f91f34c07fbaa6267dbc5e 361 Gene3D G3DSA:3.40.50.720 1 171 4.7E-24 T 29-03-2018 SMALA_RS08670 1b284a6746f91f34c07fbaa6267dbc5e 361 SUPERFAMILY SSF51735 5 158 1.25E-27 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS08670 1b284a6746f91f34c07fbaa6267dbc5e 361 Gene3D G3DSA:1.10.3660.10 173 290 9.6E-13 T 29-03-2018 SMALA_RS08495 64b6ae04cc88959095707aa001a78216 383 SUPERFAMILY SSF56672 35 230 2.11E-27 T 29-03-2018 SMALA_RS08495 64b6ae04cc88959095707aa001a78216 383 SUPERFAMILY SSF100879 236 333 3.92E-12 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 SMALA_RS08495 64b6ae04cc88959095707aa001a78216 383 Pfam PF00817 impB/mucB/samB family 39 127 7.5E-7 T 29-03-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 SMALA_RS08495 64b6ae04cc88959095707aa001a78216 383 Gene3D G3DSA:3.30.70.270 51 135 1.4E-7 T 29-03-2018 SMALA_RS08495 64b6ae04cc88959095707aa001a78216 383 Pfam PF11799 impB/mucB/samB family C-terminal domain 229 339 2.8E-12 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 SMALA_RS08495 64b6ae04cc88959095707aa001a78216 383 Gene3D G3DSA:3.30.1490.100 235 350 3.7E-20 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 SMALA_RS08495 64b6ae04cc88959095707aa001a78216 383 Gene3D G3DSA:1.10.150.20 161 234 1.0E-19 T 29-03-2018 SMALA_RS39385 9837e0e210f5ac01025fe0cad660d042 300 Gene3D G3DSA:3.40.50.300 28 208 1.7E-23 T 29-03-2018 SMALA_RS39385 9837e0e210f5ac01025fe0cad660d042 300 SMART SM00382 57 209 3.5E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS39385 9837e0e210f5ac01025fe0cad660d042 300 SUPERFAMILY SSF52540 23 288 4.01E-30 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS39385 9837e0e210f5ac01025fe0cad660d042 300 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 61 205 2.7E-19 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 SMALA_RS39385 9837e0e210f5ac01025fe0cad660d042 300 ProSitePatterns PS00674 AAA-protein family signature. 179 198 - T 29-03-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 SMALA_RS30030 c3c923bbfd22b85bb3b2a81f777cbe88 586 TIGRFAM TIGR02402 trehalose_TreZ: malto-oligosyltrehalose trehalohydrolase 3 532 8.4E-222 T 29-03-2018 IPR012768 Malto-oligosyltrehalose trehalohydrolase GO:0004553|GO:0005992 KEGG: 00500+3.2.1.141|KEGG: 00520+3.2.1.14|MetaCyc: PWY-2661|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 SMALA_RS30030 c3c923bbfd22b85bb3b2a81f777cbe88 586 SUPERFAMILY SSF51445 74 505 1.02E-108 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS30030 c3c923bbfd22b85bb3b2a81f777cbe88 586 Gene3D G3DSA:2.60.40.10 1 83 2.3E-17 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS30030 c3c923bbfd22b85bb3b2a81f777cbe88 586 SUPERFAMILY SSF81296 2 77 6.4E-16 T 29-03-2018 IPR014756 Immunoglobulin E-set SMALA_RS30030 c3c923bbfd22b85bb3b2a81f777cbe88 586 Gene3D G3DSA:3.20.20.80 88 506 2.9E-85 T 29-03-2018 SMALA_RS30030 c3c923bbfd22b85bb3b2a81f777cbe88 586 PIRSF PIRSF006337 1 550 5.1E-220 T 29-03-2018 IPR012768 Malto-oligosyltrehalose trehalohydrolase GO:0004553|GO:0005992 KEGG: 00500+3.2.1.141|KEGG: 00520+3.2.1.14|MetaCyc: PWY-2661|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 SMALA_RS30030 c3c923bbfd22b85bb3b2a81f777cbe88 586 Pfam PF00128 Alpha amylase, catalytic domain 111 190 3.6E-9 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SMALA_RS30030 c3c923bbfd22b85bb3b2a81f777cbe88 586 Pfam PF11941 Domain of unknown function (DUF3459) 490 579 7.2E-9 T 29-03-2018 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) SMALA_RS30030 c3c923bbfd22b85bb3b2a81f777cbe88 586 SMART SM00642 98 471 7.0E-8 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SMALA_RS41645 72cc985ce3b55ad90e2db29747c2bec1 483 Gene3D G3DSA:3.90.1300.10 2 483 8.0E-127 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMALA_RS41645 72cc985ce3b55ad90e2db29747c2bec1 483 Pfam PF01425 Amidase 24 464 7.1E-100 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMALA_RS41645 72cc985ce3b55ad90e2db29747c2bec1 483 ProSitePatterns PS00571 Amidases signature. 151 182 - T 29-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 SMALA_RS41645 72cc985ce3b55ad90e2db29747c2bec1 483 SUPERFAMILY SSF75304 2 475 2.49E-120 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMALA_RS05620 b765a56ada418fb2913835671212b58c 323 Pfam PF12833 Helix-turn-helix domain 224 302 7.4E-21 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS05620 b765a56ada418fb2913835671212b58c 323 SUPERFAMILY SSF46689 254 304 1.7E-10 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS05620 b765a56ada418fb2913835671212b58c 323 Pfam PF12852 Cupin 2 187 3.1E-46 T 29-03-2018 IPR032783 AraC-type transcription regulator, ligand-binding domain SMALA_RS05620 b765a56ada418fb2913835671212b58c 323 SUPERFAMILY SSF46689 202 251 5.98E-7 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS05620 b765a56ada418fb2913835671212b58c 323 Gene3D G3DSA:2.60.120.280 12 189 9.8E-16 T 29-03-2018 SMALA_RS05620 b765a56ada418fb2913835671212b58c 323 Gene3D G3DSA:1.10.10.60 257 314 1.7E-14 T 29-03-2018 SMALA_RS05620 b765a56ada418fb2913835671212b58c 323 SMART SM00342 218 301 3.5E-25 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS05620 b765a56ada418fb2913835671212b58c 323 Gene3D G3DSA:1.10.10.60 204 256 4.1E-6 T 29-03-2018 SMALA_RS23575 e6a642b66c6a79523f518780b17dc992 219 Pfam PF13305 WHG domain 107 190 8.9E-13 T 29-03-2018 IPR025996 WHG domain SMALA_RS23575 e6a642b66c6a79523f518780b17dc992 219 Gene3D G3DSA:1.10.357.10 78 215 7.1E-21 T 29-03-2018 SMALA_RS23575 e6a642b66c6a79523f518780b17dc992 219 Pfam PF00440 Bacterial regulatory proteins, tetR family 31 71 9.8E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS23575 e6a642b66c6a79523f518780b17dc992 219 SUPERFAMILY SSF48498 103 209 1.68E-15 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS23575 e6a642b66c6a79523f518780b17dc992 219 SUPERFAMILY SSF46689 18 98 4.69E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS23575 e6a642b66c6a79523f518780b17dc992 219 Gene3D G3DSA:1.10.10.60 1 77 1.3E-14 T 29-03-2018 SMALA_RS02355 59dafabaa195890a6b2f008b8e65b64d 1852 SUPERFAMILY SSF47336 1685 1768 8.64E-19 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS02355 59dafabaa195890a6b2f008b8e65b64d 1852 SMART SM00823 Phosphopantetheine attachment site 1690 1762 2.2E-22 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS02355 59dafabaa195890a6b2f008b8e65b64d 1852 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 292 409 6.0E-45 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS02355 59dafabaa195890a6b2f008b8e65b64d 1852 Pfam PF08659 KR domain 1402 1580 2.4E-59 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS02355 59dafabaa195890a6b2f008b8e65b64d 1852 SUPERFAMILY SSF52151 570 701 2.25E-69 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS02355 59dafabaa195890a6b2f008b8e65b64d 1852 SUPERFAMILY SSF52151 762 865 2.25E-69 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS02355 59dafabaa195890a6b2f008b8e65b64d 1852 Pfam PF00698 Acyl transferase domain 573 887 1.5E-52 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS02355 59dafabaa195890a6b2f008b8e65b64d 1852 Gene3D G3DSA:3.30.70.250 711 752 4.6E-16 T 29-03-2018 SMALA_RS02355 59dafabaa195890a6b2f008b8e65b64d 1852 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 412 535 4.8E-12 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS02355 59dafabaa195890a6b2f008b8e65b64d 1852 Pfam PF14765 Polyketide synthase dehydratase 937 1217 4.0E-56 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS02355 59dafabaa195890a6b2f008b8e65b64d 1852 SMART SM00825 Beta-ketoacyl synthase 36 462 8.2E-223 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS02355 59dafabaa195890a6b2f008b8e65b64d 1852 SUPERFAMILY SSF55048 700 761 2.35E-10 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS02355 59dafabaa195890a6b2f008b8e65b64d 1852 Gene3D G3DSA:1.10.1200.10 1657 1770 1.3E-17 T 29-03-2018 SMALA_RS02355 59dafabaa195890a6b2f008b8e65b64d 1852 SUPERFAMILY SSF53901 30 399 2.15E-101 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS02355 59dafabaa195890a6b2f008b8e65b64d 1852 Gene3D G3DSA:3.40.366.10 569 710 1.9E-37 T 29-03-2018 SMALA_RS02355 59dafabaa195890a6b2f008b8e65b64d 1852 Gene3D G3DSA:3.40.50.720 1221 1398 0.059 T 29-03-2018 SMALA_RS02355 59dafabaa195890a6b2f008b8e65b64d 1852 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1402 1582 3.9E-59 T 29-03-2018 SMALA_RS02355 59dafabaa195890a6b2f008b8e65b64d 1852 Pfam PF08990 Erythronolide synthase docking 2 27 1.4E-8 T 29-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 SMALA_RS02355 59dafabaa195890a6b2f008b8e65b64d 1852 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 573 869 3.1E-111 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS02355 59dafabaa195890a6b2f008b8e65b64d 1852 SMART SM00826 937 1105 4.0E-78 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS02355 59dafabaa195890a6b2f008b8e65b64d 1852 SUPERFAMILY SSF51735 1223 1386 5.72E-24 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS02355 59dafabaa195890a6b2f008b8e65b64d 1852 Gene3D G3DSA:3.40.50.720 1400 1652 1.0E-49 T 29-03-2018 SMALA_RS02355 59dafabaa195890a6b2f008b8e65b64d 1852 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 284 6.3E-85 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS02355 59dafabaa195890a6b2f008b8e65b64d 1852 Pfam PF00550 Phosphopantetheine attachment site 1692 1758 1.7E-9 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS02355 59dafabaa195890a6b2f008b8e65b64d 1852 SUPERFAMILY SSF51735 1401 1653 5.8E-48 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS02355 59dafabaa195890a6b2f008b8e65b64d 1852 Gene3D G3DSA:3.40.47.10 299 460 6.3E-63 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS02355 59dafabaa195890a6b2f008b8e65b64d 1852 Gene3D G3DSA:3.40.366.10 753 878 3.3E-29 T 29-03-2018 SMALA_RS02355 59dafabaa195890a6b2f008b8e65b64d 1852 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 197 213 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS02355 59dafabaa195890a6b2f008b8e65b64d 1852 Gene3D G3DSA:3.40.47.10 26 296 4.3E-84 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS02355 59dafabaa195890a6b2f008b8e65b64d 1852 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1717 1732 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS38680 16ad59765e51972d7fd7c58471fcd9d1 251 SMART SM00345 28 85 0.0079 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS38680 16ad59765e51972d7fd7c58471fcd9d1 251 Pfam PF00392 Bacterial regulatory proteins, gntR family 26 82 2.6E-8 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS38680 16ad59765e51972d7fd7c58471fcd9d1 251 Gene3D G3DSA:1.10.10.10 14 88 1.6E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS38680 16ad59765e51972d7fd7c58471fcd9d1 251 Gene3D G3DSA:1.20.120.530 105 245 6.4E-23 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS38680 16ad59765e51972d7fd7c58471fcd9d1 251 SMART SM00895 112 241 1.1E-13 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS38680 16ad59765e51972d7fd7c58471fcd9d1 251 SUPERFAMILY SSF46785 23 82 4.77E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS38680 16ad59765e51972d7fd7c58471fcd9d1 251 SUPERFAMILY SSF48008 109 240 7.32E-20 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS38680 16ad59765e51972d7fd7c58471fcd9d1 251 Pfam PF07729 FCD domain 115 238 1.1E-19 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS10355 fd588c1f05dca0f52151ca169a969c2d 152 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 16 147 3.6E-21 T 29-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 SMALA_RS10355 fd588c1f05dca0f52151ca169a969c2d 152 Gene3D G3DSA:3.30.530.20 1 152 1.2E-29 T 29-03-2018 IPR023393 START-like domain SMALA_RS10355 fd588c1f05dca0f52151ca169a969c2d 152 SUPERFAMILY SSF55961 6 148 6.83E-29 T 29-03-2018 SMALA_RS08970 674b944c7dc7ffb192e74d6a4cda9c55 67 Gene3D G3DSA:1.10.1200.20 1 66 1.2E-19 T 29-03-2018 IPR000290 Colicin immunity protein/pyocin immunity protein GO:0015643|GO:0030153 SMALA_RS08970 674b944c7dc7ffb192e74d6a4cda9c55 67 SUPERFAMILY SSF47345 2 50 3.27E-7 T 29-03-2018 IPR000290 Colicin immunity protein/pyocin immunity protein GO:0015643|GO:0030153 SMALA_RS08970 674b944c7dc7ffb192e74d6a4cda9c55 67 Pfam PF01320 Colicin immunity protein / pyocin immunity protein 2 57 8.0E-7 T 29-03-2018 IPR000290 Colicin immunity protein/pyocin immunity protein GO:0015643|GO:0030153 SMALA_RS08280 013f45630bf646779a79b44198171b08 249 Gene3D G3DSA:1.10.10.10 7 79 1.0E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS08280 013f45630bf646779a79b44198171b08 249 Gene3D G3DSA:3.40.1410.10 80 248 4.8E-29 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMALA_RS08280 013f45630bf646779a79b44198171b08 249 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 54 70 9.9E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS08280 013f45630bf646779a79b44198171b08 249 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 54 9.9E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS08280 013f45630bf646779a79b44198171b08 249 Pfam PF07702 UTRA domain 107 240 2.9E-24 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMALA_RS08280 013f45630bf646779a79b44198171b08 249 SMART SM00345 21 80 2.9E-10 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS08280 013f45630bf646779a79b44198171b08 249 Pfam PF00392 Bacterial regulatory proteins, gntR family 20 80 1.7E-13 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS08280 013f45630bf646779a79b44198171b08 249 SUPERFAMILY SSF64288 68 246 1.21E-32 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMALA_RS08280 013f45630bf646779a79b44198171b08 249 SUPERFAMILY SSF46785 12 84 2.6E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS08280 013f45630bf646779a79b44198171b08 249 SMART SM00866 101 241 8.8E-17 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMALA_RS38670 0918e7cd971bdf6c74bded4f7c2ed9ee 284 Pfam PF00005 ABC transporter 29 171 1.4E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS38670 0918e7cd971bdf6c74bded4f7c2ed9ee 284 SMART SM00382 37 229 2.1E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS38670 0918e7cd971bdf6c74bded4f7c2ed9ee 284 Gene3D G3DSA:3.40.50.300 9 257 4.0E-64 T 29-03-2018 SMALA_RS38670 0918e7cd971bdf6c74bded4f7c2ed9ee 284 SUPERFAMILY SSF52540 13 234 2.66E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS26470 7bbd694b7b85fbb24b87f8b1f709f98f 253 SUPERFAMILY SSF52540 4 248 2.35E-80 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS26470 7bbd694b7b85fbb24b87f8b1f709f98f 253 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS26470 7bbd694b7b85fbb24b87f8b1f709f98f 253 Gene3D G3DSA:3.40.50.300 1 253 7.5E-77 T 29-03-2018 SMALA_RS26470 7bbd694b7b85fbb24b87f8b1f709f98f 253 PIRSF PIRSF039085 1 253 4.0E-125 T 29-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 SMALA_RS26470 7bbd694b7b85fbb24b87f8b1f709f98f 253 SMART SM00382 29 226 1.3E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS26470 7bbd694b7b85fbb24b87f8b1f709f98f 253 Pfam PF00005 ABC transporter 20 178 8.0E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS38110 e8fe57bfb5ec727caca2a7caaeb41e31 209 SUPERFAMILY SSF50475 32 158 2.18E-18 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS38110 e8fe57bfb5ec727caca2a7caaeb41e31 209 Gene3D G3DSA:2.30.110.10 13 183 5.4E-29 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS38110 e8fe57bfb5ec727caca2a7caaeb41e31 209 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 35 124 5.4E-16 T 29-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 SMALA_RS38110 e8fe57bfb5ec727caca2a7caaeb41e31 209 TIGRFAM TIGR04025 PPOX_FMN_DR2398: pyridoxamine 5'-phosphate oxidase, FMN-binding family 15 207 2.9E-69 T 29-03-2018 IPR024029 Pyridoxamine 5-phosphate oxidase, FMN-dependent SMALA_RS40790 6f1d17a332f99bceaec5209956dde629 258 SUPERFAMILY SSF52540 9 253 8.67E-76 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS40790 6f1d17a332f99bceaec5209956dde629 258 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS40790 6f1d17a332f99bceaec5209956dde629 258 Pfam PF00005 ABC transporter 25 183 1.2E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS40790 6f1d17a332f99bceaec5209956dde629 258 SMART SM00382 34 231 3.4E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS40790 6f1d17a332f99bceaec5209956dde629 258 Gene3D G3DSA:3.40.50.300 6 258 6.1E-72 T 29-03-2018 SMALA_RS40790 6f1d17a332f99bceaec5209956dde629 258 PIRSF PIRSF039085 6 258 6.7E-117 T 29-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 SMALA_RS38015 26a4f154da5f51cb13ecab183e8daed4 324 Gene3D G3DSA:1.10.3720.10 21 291 7.8E-37 T 29-03-2018 SMALA_RS38015 26a4f154da5f51cb13ecab183e8daed4 324 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 119 293 1.4E-20 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS38015 26a4f154da5f51cb13ecab183e8daed4 324 SUPERFAMILY SSF161098 96 283 9.42E-24 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS12770 43f81a816bd10485546c8589095efaa2 1149 Gene3D G3DSA:3.40.50.2000 945 1132 6.3E-17 T 29-03-2018 SMALA_RS12770 43f81a816bd10485546c8589095efaa2 1149 SUPERFAMILY SSF53756 754 1140 7.53E-26 T 29-03-2018 SMALA_RS12770 43f81a816bd10485546c8589095efaa2 1149 Gene3D G3DSA:3.40.50.300 22 232 3.2E-8 T 29-03-2018 SMALA_RS12770 43f81a816bd10485546c8589095efaa2 1149 Pfam PF13692 Glycosyl transferases group 1 953 1113 2.6E-10 T 29-03-2018 SMALA_RS12770 43f81a816bd10485546c8589095efaa2 1149 Gene3D G3DSA:1.25.40.10 565 829 1.4E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS12770 43f81a816bd10485546c8589095efaa2 1149 SUPERFAMILY SSF48452 566 670 1.05E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS12770 43f81a816bd10485546c8589095efaa2 1149 Pfam PF13191 AAA ATPase domain 22 198 5.2E-12 T 29-03-2018 SMALA_RS12770 43f81a816bd10485546c8589095efaa2 1149 SUPERFAMILY SSF52540 8 100 2.74E-16 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS12770 43f81a816bd10485546c8589095efaa2 1149 SUPERFAMILY SSF52540 145 292 2.74E-16 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS30570 0e3cada84e67b010a98d938631c76c9f 74 Gene3D G3DSA:1.10.238.10 29 72 9.5E-15 T 29-03-2018 SMALA_RS30570 0e3cada84e67b010a98d938631c76c9f 74 SUPERFAMILY SSF47473 4 71 1.05E-18 T 29-03-2018 IPR011992 EF-hand domain pair SMALA_RS30570 0e3cada84e67b010a98d938631c76c9f 74 ProSitePatterns PS00018 EF-hand calcium-binding domain. 16 28 - T 29-03-2018 IPR018247 EF-Hand 1, calcium-binding site SMALA_RS30570 0e3cada84e67b010a98d938631c76c9f 74 ProSitePatterns PS00018 EF-hand calcium-binding domain. 53 65 - T 29-03-2018 IPR018247 EF-Hand 1, calcium-binding site SMALA_RS30570 0e3cada84e67b010a98d938631c76c9f 74 SMART SM00054 44 72 0.14 T 29-03-2018 IPR002048 EF-hand domain GO:0005509 SMALA_RS30570 0e3cada84e67b010a98d938631c76c9f 74 SMART SM00054 7 35 0.011 T 29-03-2018 IPR002048 EF-hand domain GO:0005509 SMALA_RS30570 0e3cada84e67b010a98d938631c76c9f 74 Pfam PF13499 EF-hand domain pair 8 65 1.5E-13 T 29-03-2018 IPR002048 EF-hand domain GO:0005509 SMALA_RS30570 0e3cada84e67b010a98d938631c76c9f 74 Gene3D G3DSA:1.10.238.10 4 28 5.5E-4 T 29-03-2018 SMALA_RS03425 259317c6c0710ed13058c3262ba84623 810 Pfam PF13802 Galactose mutarotase-like 186 252 7.3E-11 T 29-03-2018 IPR025887 Glycoside hydrolase family 31, N-terminal domain SMALA_RS03425 259317c6c0710ed13058c3262ba84623 810 SUPERFAMILY SSF51011 641 720 7.19E-20 T 29-03-2018 SMALA_RS03425 259317c6c0710ed13058c3262ba84623 810 ProSitePatterns PS00129 Glycosyl hydrolases family 31 active site. 452 459 - T 29-03-2018 IPR030458 Glycosyl hydrolases family 31, active site SMALA_RS03425 259317c6c0710ed13058c3262ba84623 810 Gene3D G3DSA:2.60.40.1760 67 287 4.9E-39 T 29-03-2018 SMALA_RS03425 259317c6c0710ed13058c3262ba84623 810 Pfam PF01055 Glycosyl hydrolases family 31 284 725 1.4E-128 T 29-03-2018 IPR000322 Glycoside hydrolase family 31 GO:0004553|GO:0005975 SMALA_RS03425 259317c6c0710ed13058c3262ba84623 810 SUPERFAMILY SSF51445 292 639 2.47E-79 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS03425 259317c6c0710ed13058c3262ba84623 810 Gene3D G3DSA:2.60.40.1180 661 721 6.9E-21 T 29-03-2018 SMALA_RS03425 259317c6c0710ed13058c3262ba84623 810 SUPERFAMILY SSF74650 74 287 1.0E-17 T 29-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 SMALA_RS03425 259317c6c0710ed13058c3262ba84623 810 Gene3D G3DSA:3.20.20.80 288 660 1.6E-136 T 29-03-2018 SMALA_RS38825 ae3ed99b77fc78ad866839871ca5f717 293 Pfam PF00005 ABC transporter 22 170 1.4E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS38825 ae3ed99b77fc78ad866839871ca5f717 293 SUPERFAMILY SSF52540 6 228 2.77E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS38825 ae3ed99b77fc78ad866839871ca5f717 293 SMART SM00382 30 214 1.6E-19 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS38825 ae3ed99b77fc78ad866839871ca5f717 293 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS38825 ae3ed99b77fc78ad866839871ca5f717 293 Gene3D G3DSA:3.40.50.300 3 247 1.2E-61 T 29-03-2018 SMALA_RS22925 5bfb87b60e5da238673d0986494153b9 257 Pfam PF00106 short chain dehydrogenase 3 188 1.1E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS22925 5bfb87b60e5da238673d0986494153b9 257 Gene3D G3DSA:3.40.50.720 2 254 5.3E-48 T 29-03-2018 SMALA_RS22925 5bfb87b60e5da238673d0986494153b9 257 PIRSF PIRSF000126 1 254 1.0E-62 T 29-03-2018 SMALA_RS22925 5bfb87b60e5da238673d0986494153b9 257 SUPERFAMILY SSF51735 3 224 3.89E-53 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS22925 5bfb87b60e5da238673d0986494153b9 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 3.4E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS22925 5bfb87b60e5da238673d0986494153b9 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 3.4E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS22925 5bfb87b60e5da238673d0986494153b9 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 167 3.4E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS22925 5bfb87b60e5da238673d0986494153b9 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 5.5E-26 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS22925 5bfb87b60e5da238673d0986494153b9 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 5.5E-26 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS22925 5bfb87b60e5da238673d0986494153b9 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 5.5E-26 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS22925 5bfb87b60e5da238673d0986494153b9 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 5.5E-26 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS22925 5bfb87b60e5da238673d0986494153b9 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 5.5E-26 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS42670 6a0550fced767b709c012cee72729b1f 104 Gene3D G3DSA:2.102.10.10 1 101 7.2E-24 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMALA_RS42670 6a0550fced767b709c012cee72729b1f 104 Pfam PF00355 Rieske [2Fe-2S] domain 3 88 2.8E-17 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMALA_RS42670 6a0550fced767b709c012cee72729b1f 104 SUPERFAMILY SSF50022 1 102 3.01E-28 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMALA_RS41710 a0f159c238582b7dd4597448871343f4 246 SUPERFAMILY SSF46785 4 71 1.55E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS41710 a0f159c238582b7dd4597448871343f4 246 Gene3D G3DSA:3.40.1410.10 70 234 2.3E-38 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMALA_RS41710 a0f159c238582b7dd4597448871343f4 246 SMART SM00866 88 228 1.9E-31 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMALA_RS41710 a0f159c238582b7dd4597448871343f4 246 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 27 41 1.1E-10 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS41710 a0f159c238582b7dd4597448871343f4 246 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 41 57 1.1E-10 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS41710 a0f159c238582b7dd4597448871343f4 246 SUPERFAMILY SSF64288 55 233 3.14E-39 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMALA_RS41710 a0f159c238582b7dd4597448871343f4 246 SMART SM00345 8 67 8.2E-18 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS41710 a0f159c238582b7dd4597448871343f4 246 Gene3D G3DSA:1.10.10.10 1 69 2.3E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS41710 a0f159c238582b7dd4597448871343f4 246 Pfam PF00392 Bacterial regulatory proteins, gntR family 6 64 2.0E-18 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS41710 a0f159c238582b7dd4597448871343f4 246 Pfam PF07702 UTRA domain 89 227 4.1E-31 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMALA_RS01745 8f2624ab937bd325ebee50dfd85dbf2c 246 SUPERFAMILY SSF51735 1 242 1.15E-71 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS01745 8f2624ab937bd325ebee50dfd85dbf2c 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 8.2E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS01745 8f2624ab937bd325ebee50dfd85dbf2c 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 8.2E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS01745 8f2624ab937bd325ebee50dfd85dbf2c 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 8.2E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS01745 8f2624ab937bd325ebee50dfd85dbf2c 246 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 241 4.5E-53 T 29-03-2018 SMALA_RS01745 8f2624ab937bd325ebee50dfd85dbf2c 246 Gene3D G3DSA:3.40.50.720 1 245 1.3E-70 T 29-03-2018 SMALA_RS01745 8f2624ab937bd325ebee50dfd85dbf2c 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 3.0E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS01745 8f2624ab937bd325ebee50dfd85dbf2c 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 3.0E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS01745 8f2624ab937bd325ebee50dfd85dbf2c 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 3.0E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS01745 8f2624ab937bd325ebee50dfd85dbf2c 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 3.0E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS01745 8f2624ab937bd325ebee50dfd85dbf2c 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 226 3.0E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS01745 8f2624ab937bd325ebee50dfd85dbf2c 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 3.0E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS19685 c7de38f9178e670d811af6ce1d4c4a1d 237 SUPERFAMILY SSF53335 27 206 1.08E-30 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS19685 c7de38f9178e670d811af6ce1d4c4a1d 237 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 14 209 23.91 T 29-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 SMALA_RS19685 c7de38f9178e670d811af6ce1d4c4a1d 237 Gene3D G3DSA:3.40.50.150 16 236 3.0E-27 T 29-03-2018 SMALA_RS19685 c7de38f9178e670d811af6ce1d4c4a1d 237 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 27 193 2.4E-37 T 29-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 SMALA_RS19685 c7de38f9178e670d811af6ce1d4c4a1d 237 Pfam PF02527 rRNA small subunit methyltransferase G 24 198 2.3E-53 T 29-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 SUPERFAMILY SSF53901 3214 3589 1.11E-104 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1947 2064 4.5E-45 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 396 513 6.4E-43 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 5299 5416 2.7E-45 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 6841 6958 1.2E-43 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 3474 3591 1.1E-44 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3150 3165 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 SUPERFAMILY SSF47336 38 153 3.4E-22 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 SUPERFAMILY SSF51735 2834 3067 3.68E-52 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 ProSitePatterns PS00012 Phosphopantetheine attachment site. 6510 6525 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 SMART SM01294 8052 8119 6.6E-5 T 29-03-2018 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 SMART SM01294 4945 5012 2.0E-5 T 29-03-2018 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 SMART SM01294 3124 3191 1.0E-7 T 29-03-2018 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 SMART SM01294 1596 1663 1.9E-6 T 29-03-2018 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 SMART SM01294 6484 6551 1.2E-7 T 29-03-2018 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 Gene3D G3DSA:3.40.366.10 855 970 8.3E-33 T 29-03-2018 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 Gene3D G3DSA:3.40.366.10 7292 7406 7.5E-31 T 29-03-2018 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 ProSitePatterns PS00012 Phosphopantetheine attachment site. 8078 8093 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 SUPERFAMILY SSF52151 7115 7236 1.78E-74 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 SUPERFAMILY SSF52151 7295 7396 1.78E-74 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 SUPERFAMILY SSF55048 803 864 1.09E-10 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 301 317 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 SUPERFAMILY SSF52151 672 804 9.94E-75 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 SUPERFAMILY SSF52151 865 964 9.94E-75 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 Pfam PF00698 Acyl transferase domain 2221 2513 7.3E-56 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 Pfam PF00698 Acyl transferase domain 5575 5887 4.9E-55 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 Pfam PF00698 Acyl transferase domain 3748 4060 2.5E-56 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 Pfam PF00698 Acyl transferase domain 676 964 1.4E-57 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 Pfam PF00698 Acyl transferase domain 7118 7433 3.4E-60 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 Pfam PF08659 KR domain 7759 7940 3.3E-62 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 Pfam PF08659 KR domain 2837 3015 3.2E-61 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 Pfam PF08659 KR domain 4658 4836 1.7E-56 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 Pfam PF08659 KR domain 1306 1484 6.2E-60 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 Pfam PF08659 KR domain 6200 6378 2.9E-60 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1852 1868 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 Gene3D G3DSA:3.40.366.10 3925 4050 3.1E-27 T 29-03-2018 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 Gene3D G3DSA:3.40.366.10 2398 2524 3.1E-28 T 29-03-2018 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 Gene3D G3DSA:3.40.366.10 5752 5877 7.5E-26 T 29-03-2018 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 SUPERFAMILY SSF52151 2219 2340 4.97E-77 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 SUPERFAMILY SSF52151 2399 2507 4.97E-77 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 Gene3D G3DSA:3.40.47.10 3218 3478 1.2E-85 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 Gene3D G3DSA:3.40.47.10 6582 6845 9.9E-86 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 Gene3D G3DSA:3.40.47.10 5044 5303 2.5E-88 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 Gene3D G3DSA:3.40.47.10 133 400 3.1E-87 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 Gene3D G3DSA:3.40.47.10 1682 1951 1.5E-86 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 SUPERFAMILY SSF55048 5699 5760 1.09E-11 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 SMART SM00826 4112 4277 2.1E-86 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 Gene3D G3DSA:3.40.50.720 4647 5043 1.6E-68 T 29-03-2018 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 SUPERFAMILY SSF51735 1086 1287 8.86E-45 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 SUPERFAMILY SSF55048 2345 2406 7.85E-11 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 5204 5220 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4971 4986 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 3749 4041 2.3E-125 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2222 2514 1.5E-128 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 7118 7415 6.7E-128 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 676 973 2.1E-131 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 5576 5868 2.5E-125 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 Gene3D G3DSA:3.40.50.720 1305 1558 1.7E-54 T 29-03-2018 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 Gene3D G3DSA:3.40.50.720 6199 6452 1.6E-54 T 29-03-2018 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 Gene3D G3DSA:3.40.50.720 7751 8014 1.8E-58 T 29-03-2018 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 Gene3D G3DSA:3.40.50.720 2829 3088 4.0E-57 T 29-03-2018 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1622 1637 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 SUPERFAMILY SSF55048 3872 3933 2.75E-11 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 SUPERFAMILY SSF47336 4939 5056 1.44E-23 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 3379 3395 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 SUPERFAMILY SSF51735 7528 7745 6.3E-42 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 SUPERFAMILY SSF51735 4656 4869 2.23E-44 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 SUPERFAMILY SSF47336 6480 6598 1.01E-22 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1306 1485 4.1E-63 T 29-03-2018 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4658 4838 2.6E-53 T 29-03-2018 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2837 3016 1.5E-62 T 29-03-2018 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6200 6379 5.8E-62 T 29-03-2018 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7759 7941 4.9E-61 T 29-03-2018 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 Gene3D G3DSA:1.10.1200.10 22 116 1.1E-19 T 29-03-2018 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 SMART SM00823 Phosphopantetheine attachment site 8051 8123 9.7E-30 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 SMART SM00823 Phosphopantetheine attachment site 4944 5016 4.2E-34 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 SMART SM00823 Phosphopantetheine attachment site 1595 1667 2.5E-32 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 SMART SM00823 Phosphopantetheine attachment site 43 115 6.9E-27 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 SMART SM00823 Phosphopantetheine attachment site 3123 3195 4.2E-34 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 SMART SM00823 Phosphopantetheine attachment site 6483 6555 1.3E-32 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 SUPERFAMILY SSF55048 7241 7302 1.83E-11 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 SUPERFAMILY SSF47336 8045 8129 4.97E-21 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 SUPERFAMILY SSF52151 3926 4034 2.3E-76 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 SUPERFAMILY SSF52151 3746 3867 2.3E-76 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 SUPERFAMILY SSF51735 4403 4594 5.9E-34 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 6746 6762 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 SUPERFAMILY SSF51735 7755 8014 1.34E-50 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 Gene3D G3DSA:3.40.47.10 403 564 1.9E-62 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 Gene3D G3DSA:3.40.47.10 1954 2115 1.3E-62 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 Gene3D G3DSA:3.40.47.10 6848 7009 7.5E-63 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 Gene3D G3DSA:3.40.47.10 5306 5467 1.5E-63 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 Gene3D G3DSA:3.40.47.10 3481 3642 2.3E-62 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 SUPERFAMILY SSF53901 1687 2062 5.08E-105 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 Gene3D G3DSA:1.10.1200.10 1570 1673 6.5E-19 T 29-03-2018 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 Gene3D G3DSA:1.10.1200.10 8015 8131 1.1E-19 T 29-03-2018 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 SUPERFAMILY SSF51735 1307 1533 6.35E-50 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1689 1939 1.1E-93 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 138 388 5.7E-93 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 5041 5291 9.5E-93 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3216 3466 8.6E-93 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 6583 6833 1.0E-92 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 SUPERFAMILY SSF53901 6579 6956 7.36E-103 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 Pfam PF14765 Polyketide synthase dehydratase 4112 4396 2.6E-53 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 Gene3D G3DSA:3.40.366.10 2218 2355 5.8E-48 T 29-03-2018 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 Gene3D G3DSA:3.40.366.10 672 813 6.9E-46 T 29-03-2018 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 Gene3D G3DSA:3.40.366.10 3745 3881 4.3E-47 T 29-03-2018 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 Gene3D G3DSA:3.40.366.10 7114 7250 1.6E-45 T 29-03-2018 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 Gene3D G3DSA:3.10.129.10 4117 4234 7.6E-7 T 29-03-2018 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 Gene3D G3DSA:3.40.366.10 5569 5713 1.2E-50 T 29-03-2018 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 SUPERFAMILY SSF52151 5573 5694 1.02E-74 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 SUPERFAMILY SSF52151 5753 5860 1.02E-74 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 SMART SM00825 Beta-ketoacyl synthase 6585 7011 7.9E-230 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 SMART SM00825 Beta-ketoacyl synthase 5043 5469 1.6E-231 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 SMART SM00825 Beta-ketoacyl synthase 140 566 1.2E-230 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 SMART SM00825 Beta-ketoacyl synthase 1691 2117 1.5E-233 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 SMART SM00825 Beta-ketoacyl synthase 3218 3644 1.2E-233 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 Pfam PF00550 Phosphopantetheine attachment site 4946 5012 3.7E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 Pfam PF00550 Phosphopantetheine attachment site 8053 8117 8.3E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 Pfam PF00550 Phosphopantetheine attachment site 1597 1663 2.5E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 Pfam PF00550 Phosphopantetheine attachment site 45 111 6.7E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 Pfam PF00550 Phosphopantetheine attachment site 3125 3191 1.2E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 Pfam PF00550 Phosphopantetheine attachment site 6485 6551 1.5E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 SUPERFAMILY SSF51735 2623 2822 1.1E-44 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 Gene3D G3DSA:1.10.1200.10 3116 3217 2.1E-20 T 29-03-2018 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 Gene3D G3DSA:1.10.1200.10 6475 6581 8.3E-21 T 29-03-2018 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 SUPERFAMILY SSF53901 5037 5413 9.28E-106 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 Gene3D G3DSA:3.30.70.250 814 854 2.6E-17 T 29-03-2018 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 Gene3D G3DSA:3.30.70.250 2356 2397 1.7E-17 T 29-03-2018 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 Gene3D G3DSA:3.30.70.250 3882 3924 4.5E-18 T 29-03-2018 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 Gene3D G3DSA:3.30.70.250 5714 5751 1.1E-18 T 29-03-2018 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 Gene3D G3DSA:3.30.70.250 7251 7291 1.8E-18 T 29-03-2018 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 SUPERFAMILY SSF53901 135 510 1.18E-104 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 SUPERFAMILY SSF47336 3117 3231 1.01E-23 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 3594 3706 8.5E-14 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2067 2183 4.2E-15 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 516 636 3.8E-14 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 5419 5527 3.8E-11 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 6961 7081 2.0E-16 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 SUPERFAMILY SSF51735 6200 6461 1.33E-51 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 SUPERFAMILY SSF51735 5983 6186 4.33E-48 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS13800 329c26150e5f84b686bf2688cad792ee 8207 SUPERFAMILY SSF47336 1592 1704 5.1E-22 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS18610 d76ae73e1be32a68aa36946333a29ec2 308 PRINTS PR00412 Epoxide hydrolase signature 44 62 1.1E-23 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS18610 d76ae73e1be32a68aa36946333a29ec2 308 PRINTS PR00412 Epoxide hydrolase signature 278 300 1.1E-23 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS18610 d76ae73e1be32a68aa36946333a29ec2 308 PRINTS PR00412 Epoxide hydrolase signature 108 121 1.1E-23 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS18610 d76ae73e1be32a68aa36946333a29ec2 308 PRINTS PR00412 Epoxide hydrolase signature 64 79 1.1E-23 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS18610 d76ae73e1be32a68aa36946333a29ec2 308 PRINTS PR00412 Epoxide hydrolase signature 244 260 1.1E-23 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS18610 d76ae73e1be32a68aa36946333a29ec2 308 PRINTS PR00412 Epoxide hydrolase signature 122 135 1.1E-23 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS18610 d76ae73e1be32a68aa36946333a29ec2 308 SUPERFAMILY SSF53474 16 303 1.35E-67 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS18610 d76ae73e1be32a68aa36946333a29ec2 308 Pfam PF12697 Alpha/beta hydrolase family 40 293 3.3E-22 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS18610 d76ae73e1be32a68aa36946333a29ec2 308 Gene3D G3DSA:3.40.50.1820 15 306 1.7E-50 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS18610 d76ae73e1be32a68aa36946333a29ec2 308 PRINTS PR00111 Alpha/beta hydrolase fold signature 122 135 4.2E-6 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS18610 d76ae73e1be32a68aa36946333a29ec2 308 PRINTS PR00111 Alpha/beta hydrolase fold signature 64 79 4.2E-6 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS18610 d76ae73e1be32a68aa36946333a29ec2 308 PRINTS PR00111 Alpha/beta hydrolase fold signature 108 121 4.2E-6 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS04470 8d61587567bdbc31be02173c5c1de369 225 SUPERFAMILY SSF52141 9 224 6.11E-71 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SMALA_RS04470 8d61587567bdbc31be02173c5c1de369 225 TIGRFAM TIGR00628 ung: uracil-DNA glycosylase 13 216 6.3E-56 T 29-03-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SMALA_RS04470 8d61587567bdbc31be02173c5c1de369 225 Pfam PF03167 Uracil DNA glycosylase superfamily 55 210 3.7E-17 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SMALA_RS04470 8d61587567bdbc31be02173c5c1de369 225 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 11 223 33.766 T 29-03-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SMALA_RS04470 8d61587567bdbc31be02173c5c1de369 225 Gene3D G3DSA:3.40.470.10 2 225 1.5E-78 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SMALA_RS04470 8d61587567bdbc31be02173c5c1de369 225 SMART SM00987 53 212 4.1E-29 T 29-03-2018 SMALA_RS04470 8d61587567bdbc31be02173c5c1de369 225 SMART SM00986 53 212 4.1E-29 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SMALA_RS04470 8d61587567bdbc31be02173c5c1de369 225 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 61 70 - T 29-03-2018 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SMALA_RS03855 0a1bbd155c2bc2a9b938277a544a359b 235 Gene3D G3DSA:3.40.50.2300 15 146 7.5E-31 T 29-03-2018 SMALA_RS03855 0a1bbd155c2bc2a9b938277a544a359b 235 ProSitePatterns PS00622 LuxR-type HTH domain signature. 185 212 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS03855 0a1bbd155c2bc2a9b938277a544a359b 235 SMART SM00421 168 225 5.3E-26 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS03855 0a1bbd155c2bc2a9b938277a544a359b 235 SUPERFAMILY SSF46894 160 228 6.46E-21 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS03855 0a1bbd155c2bc2a9b938277a544a359b 235 SMART SM00448 16 135 1.9E-20 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS03855 0a1bbd155c2bc2a9b938277a544a359b 235 Pfam PF00072 Response regulator receiver domain 18 135 3.6E-20 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS03855 0a1bbd155c2bc2a9b938277a544a359b 235 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 171 185 2.1E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS03855 0a1bbd155c2bc2a9b938277a544a359b 235 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 201 2.1E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS03855 0a1bbd155c2bc2a9b938277a544a359b 235 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 201 213 2.1E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS03855 0a1bbd155c2bc2a9b938277a544a359b 235 SUPERFAMILY SSF52172 15 148 2.13E-26 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS03855 0a1bbd155c2bc2a9b938277a544a359b 235 Pfam PF00196 Bacterial regulatory proteins, luxR family 170 225 3.5E-19 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS03855 0a1bbd155c2bc2a9b938277a544a359b 235 Gene3D G3DSA:1.10.10.10 147 232 4.2E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS14465 d4d1b49725c3b1142b4f8eb0881650a2 197 PIRSF PIRSF000709 1 170 7.3E-9 T 29-03-2018 SMALA_RS14465 d4d1b49725c3b1142b4f8eb0881650a2 197 SMART SM00855 4 153 1.4E-21 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SMALA_RS14465 d4d1b49725c3b1142b4f8eb0881650a2 197 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 5 193 2.0E-48 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SMALA_RS14465 d4d1b49725c3b1142b4f8eb0881650a2 197 Gene3D G3DSA:3.40.50.1240 1 197 2.5E-46 T 29-03-2018 IPR029033 Histidine phosphatase superfamily SMALA_RS14465 d4d1b49725c3b1142b4f8eb0881650a2 197 SUPERFAMILY SSF53254 1 196 3.64E-47 T 29-03-2018 IPR029033 Histidine phosphatase superfamily SMALA_RS17570 34ff4a59b9355f69b1e9216f87bb0db7 166 Gene3D G3DSA:2.30.110.10 1 166 1.1E-43 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS17570 34ff4a59b9355f69b1e9216f87bb0db7 166 SMART SM00903 10 164 1.3E-48 T 29-03-2018 IPR002563 Flavin reductase like domain GO:0010181 SMALA_RS17570 34ff4a59b9355f69b1e9216f87bb0db7 166 Pfam PF01613 Flavin reductase like domain 11 165 3.1E-38 T 29-03-2018 IPR002563 Flavin reductase like domain GO:0010181 SMALA_RS17570 34ff4a59b9355f69b1e9216f87bb0db7 166 SUPERFAMILY SSF50475 2 165 1.37E-41 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS13420 2cf825e8ae8684f8d9e9b5d7f36d03a9 641 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 528 538 - T 29-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site SMALA_RS13420 2cf825e8ae8684f8d9e9b5d7f36d03a9 641 Gene3D G3DSA:3.40.50.200 223 635 3.0E-37 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMALA_RS13420 2cf825e8ae8684f8d9e9b5d7f36d03a9 641 Pfam PF00082 Subtilase family 310 547 1.9E-13 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMALA_RS13420 2cf825e8ae8684f8d9e9b5d7f36d03a9 641 SUPERFAMILY SSF54897 28 197 7.65E-41 T 29-03-2018 IPR009020 Protease propeptides/proteinase inhibitor I9 SMALA_RS13420 2cf825e8ae8684f8d9e9b5d7f36d03a9 641 SMART SM00944 39 178 6.2E-43 T 29-03-2018 IPR015366 Peptidase S53, activation domain GO:0008236 Reactome: R-HSA-381038 SMALA_RS13420 2cf825e8ae8684f8d9e9b5d7f36d03a9 641 SUPERFAMILY SSF52743 611 632 3.14E-50 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMALA_RS13420 2cf825e8ae8684f8d9e9b5d7f36d03a9 641 SUPERFAMILY SSF52743 228 581 3.14E-50 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMALA_RS13420 2cf825e8ae8684f8d9e9b5d7f36d03a9 641 Pfam PF09286 Pro-kumamolisin, activation domain 43 177 7.3E-30 T 29-03-2018 IPR015366 Peptidase S53, activation domain GO:0008236 Reactome: R-HSA-381038 SMALA_RS33570 4ef0cfadd00bd5711ee891c6adabbc52 500 Gene3D G3DSA:2.30.38.10 310 403 1.2E-22 T 29-03-2018 SMALA_RS33570 4ef0cfadd00bd5711ee891c6adabbc52 500 Gene3D G3DSA:3.40.50.980 9 161 2.9E-34 T 29-03-2018 SMALA_RS33570 4ef0cfadd00bd5711ee891c6adabbc52 500 Pfam PF00501 AMP-binding enzyme 19 411 9.2E-82 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS33570 4ef0cfadd00bd5711ee891c6adabbc52 500 SUPERFAMILY SSF56801 13 498 1.96E-114 T 29-03-2018 SMALA_RS33570 4ef0cfadd00bd5711ee891c6adabbc52 500 Gene3D G3DSA:3.30.300.30 405 498 3.8E-14 T 29-03-2018 SMALA_RS33570 4ef0cfadd00bd5711ee891c6adabbc52 500 Gene3D G3DSA:3.40.50.980 162 309 5.6E-36 T 29-03-2018 SMALA_RS00445 aafd31b4300fc1c0939faa861b4dc10a 448 Gene3D G3DSA:3.50.50.60 3 217 1.2E-11 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS00445 aafd31b4300fc1c0939faa861b4dc10a 448 SUPERFAMILY SSF51905 149 363 8.42E-13 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS00445 aafd31b4300fc1c0939faa861b4dc10a 448 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 12 34 6.1E-6 T 29-03-2018 SMALA_RS00445 aafd31b4300fc1c0939faa861b4dc10a 448 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 169 178 6.1E-6 T 29-03-2018 SMALA_RS00445 aafd31b4300fc1c0939faa861b4dc10a 448 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 208 233 6.1E-6 T 29-03-2018 SMALA_RS00445 aafd31b4300fc1c0939faa861b4dc10a 448 SUPERFAMILY SSF51905 6 228 2.1E-18 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS00445 aafd31b4300fc1c0939faa861b4dc10a 448 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 208 226 1.3E-6 T 29-03-2018 SMALA_RS00445 aafd31b4300fc1c0939faa861b4dc10a 448 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 13 32 1.3E-6 T 29-03-2018 SMALA_RS00445 aafd31b4300fc1c0939faa861b4dc10a 448 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 166 184 1.3E-6 T 29-03-2018 SMALA_RS00445 aafd31b4300fc1c0939faa861b4dc10a 448 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 10 355 1.6E-108 T 29-03-2018 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase SMALA_RS00445 aafd31b4300fc1c0939faa861b4dc10a 448 Gene3D G3DSA:3.50.50.60 218 445 3.8E-16 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS06090 52a3f95aca1f2e38d27269ba485b8249 287 Gene3D G3DSA:3.40.50.720 1 261 4.7E-55 T 29-03-2018 SMALA_RS06090 52a3f95aca1f2e38d27269ba485b8249 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 150 6.2E-15 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS06090 52a3f95aca1f2e38d27269ba485b8249 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 169 6.2E-15 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS06090 52a3f95aca1f2e38d27269ba485b8249 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 105 121 6.2E-15 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS06090 52a3f95aca1f2e38d27269ba485b8249 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 59 70 6.2E-15 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS06090 52a3f95aca1f2e38d27269ba485b8249 287 Pfam PF00106 short chain dehydrogenase 2 170 1.1E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS06090 52a3f95aca1f2e38d27269ba485b8249 287 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 111 119 6.4E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS06090 52a3f95aca1f2e38d27269ba485b8249 287 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 59 70 6.4E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS06090 52a3f95aca1f2e38d27269ba485b8249 287 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 150 6.4E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS06090 52a3f95aca1f2e38d27269ba485b8249 287 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 118 146 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMALA_RS06090 52a3f95aca1f2e38d27269ba485b8249 287 SUPERFAMILY SSF51735 1 248 1.29E-49 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS19050 075354c15da354c62d65251400a32cd5 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 120 137 9.9E-73 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMALA_RS19050 075354c15da354c62d65251400a32cd5 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 5 24 9.9E-73 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMALA_RS19050 075354c15da354c62d65251400a32cd5 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 211 223 9.9E-73 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMALA_RS19050 075354c15da354c62d65251400a32cd5 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 31 44 9.9E-73 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMALA_RS19050 075354c15da354c62d65251400a32cd5 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 93 109 9.9E-73 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMALA_RS19050 075354c15da354c62d65251400a32cd5 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 261 283 9.9E-73 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMALA_RS19050 075354c15da354c62d65251400a32cd5 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 138 156 9.9E-73 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMALA_RS19050 075354c15da354c62d65251400a32cd5 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 176 193 9.9E-73 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMALA_RS19050 075354c15da354c62d65251400a32cd5 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 158 174 9.9E-73 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMALA_RS19050 075354c15da354c62d65251400a32cd5 341 ProSitePatterns PS00433 Phosphofructokinase signature. 265 283 - T 29-03-2018 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMALA_RS19050 075354c15da354c62d65251400a32cd5 341 Hamap MF_01976 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase [pfp]. 1 341 42.515 T 29-03-2018 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 SMALA_RS19050 075354c15da354c62d65251400a32cd5 341 Gene3D G3DSA:3.40.50.450 198 322 8.2E-16 T 29-03-2018 SMALA_RS19050 075354c15da354c62d65251400a32cd5 341 Pfam PF00365 Phosphofructokinase 2 296 6.4E-104 T 29-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMALA_RS19050 075354c15da354c62d65251400a32cd5 341 PIRSF PIRSF000532 1 338 5.9E-121 T 29-03-2018 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 SMALA_RS19050 075354c15da354c62d65251400a32cd5 341 TIGRFAM TIGR02483 PFK_mixed: phosphofructokinase 2 321 3.9E-147 T 29-03-2018 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 SMALA_RS19050 075354c15da354c62d65251400a32cd5 341 Gene3D G3DSA:3.40.50.450 1 197 5.7E-77 T 29-03-2018 SMALA_RS19050 075354c15da354c62d65251400a32cd5 341 SUPERFAMILY SSF53784 1 331 2.49E-120 T 29-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMALA_RS36315 0f021512e82c0b9036670656f728d424 440 Gene3D G3DSA:3.40.190.10 172 387 1.0E-42 T 29-03-2018 SMALA_RS36315 0f021512e82c0b9036670656f728d424 440 Gene3D G3DSA:3.40.190.10 41 171 1.7E-23 T 29-03-2018 SMALA_RS36315 0f021512e82c0b9036670656f728d424 440 Pfam PF01547 Bacterial extracellular solute-binding protein 58 351 7.9E-46 T 29-03-2018 IPR006059 Solute-binding family 1 GO:0006810 SMALA_RS36315 0f021512e82c0b9036670656f728d424 440 SUPERFAMILY SSF53850 41 436 2.28E-72 T 29-03-2018 SMALA_RS05140 a46a9eff90067ee06fb86c08dca420cf 383 SUPERFAMILY SSF51445 49 373 8.65E-55 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS05140 a46a9eff90067ee06fb86c08dca420cf 383 ProSitePatterns PS01095 Chitinases family 18 active site. 161 169 - T 29-03-2018 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 SMALA_RS05140 a46a9eff90067ee06fb86c08dca420cf 383 Gene3D G3DSA:3.20.20.80 47 380 5.3E-43 T 29-03-2018 SMALA_RS05140 a46a9eff90067ee06fb86c08dca420cf 383 SMART SM00636 49 366 1.6E-6 T 29-03-2018 IPR011583 Chitinase II GO:0008061 SMALA_RS05140 a46a9eff90067ee06fb86c08dca420cf 383 Pfam PF00704 Glycosyl hydrolases family 18 51 327 3.5E-26 T 29-03-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 SMALA_RS21355 35e5c863c08667979223b3aa6a532cbb 329 SUPERFAMILY SSF161098 68 313 2.35E-32 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS21355 35e5c863c08667979223b3aa6a532cbb 329 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 29 321 6.5E-88 T 29-03-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 SMALA_RS21355 35e5c863c08667979223b3aa6a532cbb 329 Gene3D G3DSA:1.10.3720.10 25 315 1.4E-33 T 29-03-2018 SMALA_RS21355 35e5c863c08667979223b3aa6a532cbb 329 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 108 320 8.4E-16 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS41920 354790c75cd5352e5503ad4a260dcccc 589 SMART SM00382 359 551 2.7E-19 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS41920 354790c75cd5352e5503ad4a260dcccc 589 SMART SM00382 27 222 1.3E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS41920 354790c75cd5352e5503ad4a260dcccc 589 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS41920 354790c75cd5352e5503ad4a260dcccc 589 ProSitePatterns PS00211 ABC transporters family signature. 474 488 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS41920 354790c75cd5352e5503ad4a260dcccc 589 Gene3D G3DSA:3.40.50.300 328 587 1.6E-68 T 29-03-2018 SMALA_RS41920 354790c75cd5352e5503ad4a260dcccc 589 Gene3D G3DSA:3.40.50.300 1 321 4.2E-72 T 29-03-2018 SMALA_RS41920 354790c75cd5352e5503ad4a260dcccc 589 SUPERFAMILY SSF52540 2 251 1.6E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS41920 354790c75cd5352e5503ad4a260dcccc 589 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 222 306 1.7E-22 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMALA_RS41920 354790c75cd5352e5503ad4a260dcccc 589 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 224 287 3.4E-21 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMALA_RS41920 354790c75cd5352e5503ad4a260dcccc 589 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 554 580 9.4E-5 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMALA_RS41920 354790c75cd5352e5503ad4a260dcccc 589 Pfam PF00005 ABC transporter 19 172 3.3E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS41920 354790c75cd5352e5503ad4a260dcccc 589 Pfam PF00005 ABC transporter 352 502 3.0E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS41920 354790c75cd5352e5503ad4a260dcccc 589 SUPERFAMILY SSF52540 331 573 1.87E-66 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS28635 b1c7e661356d362183279936922c2c6e 685 Gene3D G3DSA:1.10.510.10 100 276 1.1E-37 T 29-03-2018 SMALA_RS28635 b1c7e661356d362183279936922c2c6e 685 Pfam PF13360 PQQ-like domain 470 668 1.5E-17 T 29-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat SMALA_RS28635 b1c7e661356d362183279936922c2c6e 685 SMART SM00564 621 655 190.0 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMALA_RS28635 b1c7e661356d362183279936922c2c6e 685 SMART SM00564 378 409 0.22 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMALA_RS28635 b1c7e661356d362183279936922c2c6e 685 SMART SM00564 500 532 17.0 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMALA_RS28635 b1c7e661356d362183279936922c2c6e 685 SMART SM00564 457 488 260.0 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMALA_RS28635 b1c7e661356d362183279936922c2c6e 685 SMART SM00564 541 570 1.1 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMALA_RS28635 b1c7e661356d362183279936922c2c6e 685 SMART SM00564 418 449 0.25 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMALA_RS28635 b1c7e661356d362183279936922c2c6e 685 SUPERFAMILY SSF50998 370 584 2.58E-25 T 29-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily SMALA_RS28635 b1c7e661356d362183279936922c2c6e 685 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 21 43 - T 29-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 SMALA_RS28635 b1c7e661356d362183279936922c2c6e 685 Pfam PF00069 Protein kinase domain 16 256 7.9E-37 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMALA_RS28635 b1c7e661356d362183279936922c2c6e 685 Pfam PF13570 PQQ-like domain 402 441 2.0E-4 T 29-03-2018 IPR025666 Pyrrolo-quinoline quinone-like domain SMALA_RS28635 b1c7e661356d362183279936922c2c6e 685 SUPERFAMILY SSF50998 538 671 2.24E-8 T 29-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily SMALA_RS28635 b1c7e661356d362183279936922c2c6e 685 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 133 145 - T 29-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMALA_RS28635 b1c7e661356d362183279936922c2c6e 685 SMART SM00220 15 259 7.9E-38 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMALA_RS28635 b1c7e661356d362183279936922c2c6e 685 Gene3D G3DSA:2.140.10.10 605 683 1.9E-5 T 29-03-2018 SMALA_RS28635 b1c7e661356d362183279936922c2c6e 685 Gene3D G3DSA:2.140.10.10 490 604 1.5E-18 T 29-03-2018 SMALA_RS28635 b1c7e661356d362183279936922c2c6e 685 Gene3D G3DSA:2.140.10.10 277 489 1.5E-19 T 29-03-2018 SMALA_RS28635 b1c7e661356d362183279936922c2c6e 685 Gene3D G3DSA:3.30.200.20 10 99 1.4E-14 T 29-03-2018 SMALA_RS28635 b1c7e661356d362183279936922c2c6e 685 SUPERFAMILY SSF56112 12 256 3.37E-59 T 29-03-2018 IPR011009 Protein kinase-like domain SMALA_RS30915 0dc87526c637c9b2a9903e095a8b62c2 147 PIRSF PIRSF017371 1 147 5.0E-71 T 29-03-2018 IPR014488 Uncharacterised conserved protein UCP017371 SMALA_RS30915 0dc87526c637c9b2a9903e095a8b62c2 147 SUPERFAMILY SSF55961 3 141 6.6E-20 T 29-03-2018 SMALA_RS30915 0dc87526c637c9b2a9903e095a8b62c2 147 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 4 144 2.7E-22 T 29-03-2018 IPR019587 Polyketide cyclase/dehydrase SMALA_RS30915 0dc87526c637c9b2a9903e095a8b62c2 147 Gene3D G3DSA:3.30.530.20 3 146 9.1E-20 T 29-03-2018 IPR023393 START-like domain SMALA_RS20140 bac86a7d03364047c7b27db2e7249624 383 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 55 370 1.4E-51 T 29-03-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 SMALA_RS20140 bac86a7d03364047c7b27db2e7249624 383 Pfam PF04261 Dyp-type peroxidase family 55 370 5.1E-52 T 29-03-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 SMALA_RS20140 bac86a7d03364047c7b27db2e7249624 383 SUPERFAMILY SSF54909 52 373 1.2E-53 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel SMALA_RS18735 daa3ff0ba418f6f3bccd48e80ee8af7f 259 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 128 237 1.7E-5 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMALA_RS18735 daa3ff0ba418f6f3bccd48e80ee8af7f 259 SUPERFAMILY SSF54593 2 153 1.13E-17 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS18735 daa3ff0ba418f6f3bccd48e80ee8af7f 259 SUPERFAMILY SSF54593 126 245 2.82E-19 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS18735 daa3ff0ba418f6f3bccd48e80ee8af7f 259 Gene3D G3DSA:3.10.180.10 124 256 2.3E-19 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS18735 daa3ff0ba418f6f3bccd48e80ee8af7f 259 Gene3D G3DSA:3.10.180.10 1 115 7.3E-16 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS15465 1aaacfc3cd049a0289bd730b89c53e24 243 Gene3D G3DSA:1.10.10.60 29 82 4.6E-18 T 29-03-2018 SMALA_RS15465 1aaacfc3cd049a0289bd730b89c53e24 243 Pfam PF00440 Bacterial regulatory proteins, tetR family 41 83 1.1E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS15465 1aaacfc3cd049a0289bd730b89c53e24 243 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 54 7.7E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS15465 1aaacfc3cd049a0289bd730b89c53e24 243 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 62 85 7.7E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS15465 1aaacfc3cd049a0289bd730b89c53e24 243 SUPERFAMILY SSF46689 29 110 8.03E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS15465 1aaacfc3cd049a0289bd730b89c53e24 243 Gene3D G3DSA:1.10.357.10 83 238 4.2E-24 T 29-03-2018 SMALA_RS37390 712ed18f8506007e6178c173251c143a 484 PRINTS PR00344 Bacterial sensor protein C-terminal signature 404 418 3.9E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS37390 712ed18f8506007e6178c173251c143a 484 PRINTS PR00344 Bacterial sensor protein C-terminal signature 422 432 3.9E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS37390 712ed18f8506007e6178c173251c143a 484 PRINTS PR00344 Bacterial sensor protein C-terminal signature 439 457 3.9E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS37390 712ed18f8506007e6178c173251c143a 484 PRINTS PR00344 Bacterial sensor protein C-terminal signature 462 475 3.9E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS37390 712ed18f8506007e6178c173251c143a 484 SUPERFAMILY SSF55874 312 476 7.47E-40 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS37390 712ed18f8506007e6178c173251c143a 484 Pfam PF00672 HAMP domain 188 242 6.3E-8 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMALA_RS37390 712ed18f8506007e6178c173251c143a 484 Gene3D G3DSA:1.10.287.130 246 319 9.3E-18 T 29-03-2018 SMALA_RS37390 712ed18f8506007e6178c173251c143a 484 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 366 476 3.1E-24 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS37390 712ed18f8506007e6178c173251c143a 484 SMART SM00387 366 478 5.7E-39 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS37390 712ed18f8506007e6178c173251c143a 484 Pfam PF00512 His Kinase A (phospho-acceptor) domain 257 323 3.7E-18 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS37390 712ed18f8506007e6178c173251c143a 484 SMART SM00388 256 323 1.2E-22 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS37390 712ed18f8506007e6178c173251c143a 484 SUPERFAMILY SSF47384 244 324 4.12E-20 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS37390 712ed18f8506007e6178c173251c143a 484 Gene3D G3DSA:3.30.565.10 326 482 2.9E-40 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS37390 712ed18f8506007e6178c173251c143a 484 SMART SM00304 188 248 1.7E-6 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMALA_RS19995 6285602ffef7890bac33e1b03882d515 351 SUPERFAMILY SSF51735 138 277 3.05E-28 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS19995 6285602ffef7890bac33e1b03882d515 351 Gene3D G3DSA:1.10.287.70 29 131 4.7E-17 T 29-03-2018 SMALA_RS19995 6285602ffef7890bac33e1b03882d515 351 Pfam PF07885 Ion channel 41 121 3.4E-13 T 29-03-2018 IPR013099 Potassium channel domain SMALA_RS19995 6285602ffef7890bac33e1b03882d515 351 SUPERFAMILY SSF81324 32 158 5.76E-20 T 29-03-2018 SMALA_RS19995 6285602ffef7890bac33e1b03882d515 351 Pfam PF02254 TrkA-N domain 143 259 1.6E-27 T 29-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 SMALA_RS19995 6285602ffef7890bac33e1b03882d515 351 Gene3D G3DSA:3.40.50.720 132 259 1.9E-25 T 29-03-2018 SMALA_RS11775 735eb79e1cbd785ba5702a52fcd86c11 719 Pfam PF00486 Transcriptional regulatory protein, C terminal 35 97 2.1E-6 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS11775 735eb79e1cbd785ba5702a52fcd86c11 719 Pfam PF00931 NB-ARC domain 303 542 4.5E-15 T 29-03-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207 SMALA_RS11775 735eb79e1cbd785ba5702a52fcd86c11 719 Pfam PF03704 Bacterial transcriptional activator domain 104 248 6.0E-38 T 29-03-2018 IPR005158 Bacterial transcriptional activator domain SMALA_RS11775 735eb79e1cbd785ba5702a52fcd86c11 719 Gene3D G3DSA:1.10.10.10 1 100 4.5E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS11775 735eb79e1cbd785ba5702a52fcd86c11 719 Gene3D G3DSA:1.25.40.10 101 271 3.5E-23 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS11775 735eb79e1cbd785ba5702a52fcd86c11 719 SMART SM00862 23 97 3.3E-4 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS11775 735eb79e1cbd785ba5702a52fcd86c11 719 SUPERFAMILY SSF46894 13 97 2.83E-9 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS11775 735eb79e1cbd785ba5702a52fcd86c11 719 SUPERFAMILY SSF52540 275 540 1.31E-31 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS11775 735eb79e1cbd785ba5702a52fcd86c11 719 Gene3D G3DSA:3.40.50.300 272 426 9.8E-19 T 29-03-2018 SMALA_RS11775 735eb79e1cbd785ba5702a52fcd86c11 719 SUPERFAMILY SSF48452 99 259 3.04E-35 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS11775 735eb79e1cbd785ba5702a52fcd86c11 719 SMART SM01043 104 248 1.2E-43 T 29-03-2018 IPR005158 Bacterial transcriptional activator domain SMALA_RS11775 735eb79e1cbd785ba5702a52fcd86c11 719 PRINTS PR00364 Disease resistance protein signature 387 401 1.6E-11 T 29-03-2018 SMALA_RS11775 735eb79e1cbd785ba5702a52fcd86c11 719 PRINTS PR00364 Disease resistance protein signature 308 323 1.6E-11 T 29-03-2018 SMALA_RS11775 735eb79e1cbd785ba5702a52fcd86c11 719 PRINTS PR00364 Disease resistance protein signature 472 486 1.6E-11 T 29-03-2018 SMALA_RS32410 3dd86f70fc2dbbc56dba6f1afcd0dacd 484 Gene3D G3DSA:3.90.1150.10 354 483 1.8E-28 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS32410 3dd86f70fc2dbbc56dba6f1afcd0dacd 484 SUPERFAMILY SSF53383 111 479 1.01E-80 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS32410 3dd86f70fc2dbbc56dba6f1afcd0dacd 484 Gene3D G3DSA:3.40.640.10 130 353 6.9E-39 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS32410 3dd86f70fc2dbbc56dba6f1afcd0dacd 484 Gene3D G3DSA:1.10.10.10 1 66 1.6E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS32410 3dd86f70fc2dbbc56dba6f1afcd0dacd 484 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 66 5.5E-12 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS32410 3dd86f70fc2dbbc56dba6f1afcd0dacd 484 SMART SM00345 10 67 2.5E-9 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS32410 3dd86f70fc2dbbc56dba6f1afcd0dacd 484 SUPERFAMILY SSF46785 19 71 1.22E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS32410 3dd86f70fc2dbbc56dba6f1afcd0dacd 484 Pfam PF00155 Aminotransferase class I and II 130 460 2.7E-25 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMALA_RS01965 163d7b4190d2854faad67193466a6cda 435 SUPERFAMILY SSF53850 41 426 5.25E-48 T 29-03-2018 SMALA_RS01965 163d7b4190d2854faad67193466a6cda 435 Pfam PF01547 Bacterial extracellular solute-binding protein 64 311 4.1E-17 T 29-03-2018 IPR006059 Solute-binding family 1 GO:0006810 SMALA_RS01965 163d7b4190d2854faad67193466a6cda 435 Gene3D G3DSA:3.40.190.10 159 434 7.9E-26 T 29-03-2018 SMALA_RS31500 4705bfeee55868b7da07224258f21248 272 Pfam PF07702 UTRA domain 107 246 9.5E-32 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMALA_RS31500 4705bfeee55868b7da07224258f21248 272 SUPERFAMILY SSF46785 20 89 2.52E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS31500 4705bfeee55868b7da07224258f21248 272 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 46 60 2.2E-8 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS31500 4705bfeee55868b7da07224258f21248 272 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 60 76 2.2E-8 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS31500 4705bfeee55868b7da07224258f21248 272 SUPERFAMILY SSF64288 74 254 5.02E-40 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMALA_RS31500 4705bfeee55868b7da07224258f21248 272 Pfam PF00392 Bacterial regulatory proteins, gntR family 25 86 3.6E-19 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS31500 4705bfeee55868b7da07224258f21248 272 Gene3D G3DSA:1.10.10.10 14 85 4.0E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS31500 4705bfeee55868b7da07224258f21248 272 SMART SM00345 27 86 2.6E-19 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS31500 4705bfeee55868b7da07224258f21248 272 Gene3D G3DSA:3.40.1410.10 86 255 1.6E-37 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMALA_RS31500 4705bfeee55868b7da07224258f21248 272 SMART SM00866 107 247 2.8E-26 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMALA_RS42125 508ccdf39fe4a1b20e1550fc11428247 129 SUPERFAMILY SSF54909 1 117 3.22E-15 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel SMALA_RS42125 508ccdf39fe4a1b20e1550fc11428247 129 Pfam PF05336 L-rhamnose mutarotase 4 116 1.2E-17 T 29-03-2018 IPR008000 Rhamnose/fucose mutarotase GO:0005737|GO:0016857 SMALA_RS23070 10dd720fbe98a23b3f39619af33656fe 205 SUPERFAMILY SSF50475 41 199 6.38E-48 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS23070 10dd720fbe98a23b3f39619af33656fe 205 SMART SM00903 50 200 1.5E-57 T 29-03-2018 IPR002563 Flavin reductase like domain GO:0010181 SMALA_RS23070 10dd720fbe98a23b3f39619af33656fe 205 Pfam PF01613 Flavin reductase like domain 51 199 7.2E-37 T 29-03-2018 IPR002563 Flavin reductase like domain GO:0010181 SMALA_RS23070 10dd720fbe98a23b3f39619af33656fe 205 Gene3D G3DSA:2.30.110.10 38 204 2.5E-49 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS34835 b93bffc7e8d6cba3128fc011cdd0b106 526 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 241 349 1.4E-5 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS34835 b93bffc7e8d6cba3128fc011cdd0b106 526 SMART SM00387 237 351 0.0064 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS34835 b93bffc7e8d6cba3128fc011cdd0b106 526 SUPERFAMILY SSF55874 227 350 3.41E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS34835 b93bffc7e8d6cba3128fc011cdd0b106 526 Gene3D G3DSA:3.30.565.10 46 349 1.2E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS39295 d34dd9fb18b896c9d964dfe9e307c5ee 179 Gene3D G3DSA:3.40.630.30 1 166 3.0E-26 T 29-03-2018 SMALA_RS39295 d34dd9fb18b896c9d964dfe9e307c5ee 179 Pfam PF13302 Acetyltransferase (GNAT) domain 8 148 5.7E-35 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SMALA_RS39295 d34dd9fb18b896c9d964dfe9e307c5ee 179 SUPERFAMILY SSF55729 1 149 9.72E-41 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS36050 5c380e4a530fefc471ca18c94c8aac50 403 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 149 164 3.0E-17 T 29-03-2018 SMALA_RS36050 5c380e4a530fefc471ca18c94c8aac50 403 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 3.0E-17 T 29-03-2018 SMALA_RS36050 5c380e4a530fefc471ca18c94c8aac50 403 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 284 299 3.0E-17 T 29-03-2018 SMALA_RS36050 5c380e4a530fefc471ca18c94c8aac50 403 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 299 315 3.0E-17 T 29-03-2018 SMALA_RS36050 5c380e4a530fefc471ca18c94c8aac50 403 Gene3D G3DSA:3.50.50.60 2 352 3.0E-38 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS36050 5c380e4a530fefc471ca18c94c8aac50 403 SUPERFAMILY SSF51905 3 170 1.35E-48 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS36050 5c380e4a530fefc471ca18c94c8aac50 403 SUPERFAMILY SSF51905 271 357 1.35E-48 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS36050 5c380e4a530fefc471ca18c94c8aac50 403 Pfam PF01494 FAD binding domain 2 345 4.6E-24 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 SMALA_RS00645 a45cbe81c5111077e92b2ee590b4948e 686 Pfam PF04185 Phosphoesterase family 44 427 2.1E-116 T 29-03-2018 IPR007312 Phosphoesterase GO:0016788 SMALA_RS00645 a45cbe81c5111077e92b2ee590b4948e 686 TIGRFAM TIGR03396 PC_PLC: phospholipase C, phosphocholine-specific 5 683 2.6E-261 T 29-03-2018 IPR017767 Bacterial phospholipase C, phosphocholine-specific GO:0034480 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 SMALA_RS00645 a45cbe81c5111077e92b2ee590b4948e 686 Gene3D G3DSA:3.40.720.10 114 432 6.4E-27 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 SMALA_RS00645 a45cbe81c5111077e92b2ee590b4948e 686 Pfam PF05506 Domain of unknown function (DUF756) 495 583 1.1E-21 T 29-03-2018 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 SMALA_RS00645 a45cbe81c5111077e92b2ee590b4948e 686 Pfam PF05506 Domain of unknown function (DUF756) 589 670 2.0E-14 T 29-03-2018 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 SMALA_RS03000 04eb24b3afa34057ffe7ff8d17236ca0 388 SUPERFAMILY SSF90002 245 307 8.11E-9 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal SMALA_RS03000 04eb24b3afa34057ffe7ff8d17236ca0 388 SUPERFAMILY SSF90002 334 360 8.11E-9 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal SMALA_RS03000 04eb24b3afa34057ffe7ff8d17236ca0 388 SMART SM00833 244 360 1.0E-36 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal SMALA_RS03000 04eb24b3afa34057ffe7ff8d17236ca0 388 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 245 360 1.5E-17 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal SMALA_RS03000 04eb24b3afa34057ffe7ff8d17236ca0 388 Gene3D G3DSA:3.40.50.300 5 201 3.5E-6 T 29-03-2018 SMALA_RS03000 04eb24b3afa34057ffe7ff8d17236ca0 388 Gene3D G3DSA:3.30.1220.10 223 361 1.5E-18 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal SMALA_RS27730 98a0eb22624839d36a873470c3350ef0 533 Gene3D G3DSA:3.40.50.720 8 117 5.9E-32 T 29-03-2018 SMALA_RS27730 98a0eb22624839d36a873470c3350ef0 533 SUPERFAMILY SSF52283 8 140 8.13E-37 T 29-03-2018 SMALA_RS27730 98a0eb22624839d36a873470c3350ef0 533 SUPERFAMILY SSF55021 459 530 1.12E-13 T 29-03-2018 SMALA_RS27730 98a0eb22624839d36a873470c3350ef0 533 Gene3D G3DSA:3.30.1330.90 320 457 1.6E-31 T 29-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 SMALA_RS27730 98a0eb22624839d36a873470c3350ef0 533 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 149 176 - T 29-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 SMALA_RS27730 98a0eb22624839d36a873470c3350ef0 533 Gene3D G3DSA:3.30.70.260 460 533 2.1E-15 T 29-03-2018 SMALA_RS27730 98a0eb22624839d36a873470c3350ef0 533 TIGRFAM TIGR01327 PGDH: phosphoglycerate dehydrogenase 11 531 1.4E-187 T 29-03-2018 IPR006236 D-3-phosphoglycerate dehydrogenase GO:0004617|GO:0006564 KEGG: 00260+1.1.1.95|KEGG: 00680+1.1.1.95|Reactome: R-HSA-977347 SMALA_RS27730 98a0eb22624839d36a873470c3350ef0 533 Gene3D G3DSA:3.40.50.720 118 289 2.4E-58 T 29-03-2018 SMALA_RS27730 98a0eb22624839d36a873470c3350ef0 533 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 11 318 1.4E-32 T 29-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 SMALA_RS27730 98a0eb22624839d36a873470c3350ef0 533 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 197 219 - T 29-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site SMALA_RS27730 98a0eb22624839d36a873470c3350ef0 533 SUPERFAMILY SSF143548 325 454 4.71E-33 T 29-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 SMALA_RS27730 98a0eb22624839d36a873470c3350ef0 533 SUPERFAMILY SSF51735 107 286 1.14E-59 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS27730 98a0eb22624839d36a873470c3350ef0 533 Pfam PF01842 ACT domain 463 520 3.6E-8 T 29-03-2018 IPR002912 ACT domain SMALA_RS27730 98a0eb22624839d36a873470c3350ef0 533 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 226 242 - T 29-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site SMALA_RS27730 98a0eb22624839d36a873470c3350ef0 533 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 113 286 7.9E-63 T 29-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 SMALA_RS20650 3c040ff5b3b148b4be6334b1ccf85928 622 SUPERFAMILY SSF100920 355 511 9.94E-60 T 29-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 SMALA_RS20650 3c040ff5b3b148b4be6334b1ccf85928 622 Gene3D G3DSA:3.30.420.40 1 170 4.0E-67 T 29-03-2018 SMALA_RS20650 3c040ff5b3b148b4be6334b1ccf85928 622 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 611 36.097 T 29-03-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613 SMALA_RS20650 3c040ff5b3b148b4be6334b1ccf85928 622 SUPERFAMILY SSF53067 4 160 2.96E-57 T 29-03-2018 SMALA_RS20650 3c040ff5b3b148b4be6334b1ccf85928 622 Gene3D G3DSA:2.60.34.10 361 502 8.7E-70 T 29-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 SMALA_RS20650 3c040ff5b3b148b4be6334b1ccf85928 622 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 307 321 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 SMALA_RS20650 3c040ff5b3b148b4be6334b1ccf85928 622 Gene3D G3DSA:1.20.1270.10 503 589 7.9E-24 T 29-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain SMALA_RS20650 3c040ff5b3b148b4be6334b1ccf85928 622 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 166 179 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 SMALA_RS20650 3c040ff5b3b148b4be6334b1ccf85928 622 PRINTS PR00301 70kDa heat shock protein signature 336 356 1.7E-74 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SMALA_RS20650 3c040ff5b3b148b4be6334b1ccf85928 622 PRINTS PR00301 70kDa heat shock protein signature 114 134 1.7E-74 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SMALA_RS20650 3c040ff5b3b148b4be6334b1ccf85928 622 PRINTS PR00301 70kDa heat shock protein signature 304 320 1.7E-74 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SMALA_RS20650 3c040ff5b3b148b4be6334b1ccf85928 622 PRINTS PR00301 70kDa heat shock protein signature 31 43 1.7E-74 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SMALA_RS20650 3c040ff5b3b148b4be6334b1ccf85928 622 PRINTS PR00301 70kDa heat shock protein signature 359 378 1.7E-74 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SMALA_RS20650 3c040ff5b3b148b4be6334b1ccf85928 622 PRINTS PR00301 70kDa heat shock protein signature 440 456 1.7E-74 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SMALA_RS20650 3c040ff5b3b148b4be6334b1ccf85928 622 PRINTS PR00301 70kDa heat shock protein signature 172 182 1.7E-74 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SMALA_RS20650 3c040ff5b3b148b4be6334b1ccf85928 622 PRINTS PR00301 70kDa heat shock protein signature 3 16 1.7E-74 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SMALA_RS20650 3c040ff5b3b148b4be6334b1ccf85928 622 PRINTS PR00301 70kDa heat shock protein signature 54 62 1.7E-74 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SMALA_RS20650 3c040ff5b3b148b4be6334b1ccf85928 622 Gene3D G3DSA:3.30.420.40 171 333 2.5E-49 T 29-03-2018 SMALA_RS20650 3c040ff5b3b148b4be6334b1ccf85928 622 SUPERFAMILY SSF100934 478 579 1.83E-16 T 29-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain SMALA_RS20650 3c040ff5b3b148b4be6334b1ccf85928 622 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 SMALA_RS20650 3c040ff5b3b148b4be6334b1ccf85928 622 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 4 574 1.8E-278 T 29-03-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613 SMALA_RS20650 3c040ff5b3b148b4be6334b1ccf85928 622 SUPERFAMILY SSF53067 161 353 9.26E-66 T 29-03-2018 SMALA_RS20650 3c040ff5b3b148b4be6334b1ccf85928 622 Pfam PF00012 Hsp70 protein 80 574 1.1E-221 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SMALA_RS20650 3c040ff5b3b148b4be6334b1ccf85928 622 Pfam PF00012 Hsp70 protein 4 78 5.3E-29 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SMALA_RS29135 c2613a231930fc963b37cd45aebdc986 413 SUPERFAMILY SSF53649 61 409 1.18E-61 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 SMALA_RS29135 c2613a231930fc963b37cd45aebdc986 413 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 65 398 1.4E-45 T 29-03-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 SMALA_RS29135 c2613a231930fc963b37cd45aebdc986 413 Gene3D G3DSA:3.40.720.10 55 409 1.4E-30 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 SMALA_RS36010 a17d28c5c4e65c0f17b280981ec905b8 404 Gene3D G3DSA:3.30.565.10 152 398 1.4E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS36010 a17d28c5c4e65c0f17b280981ec905b8 404 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 301 396 5.9E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS36010 a17d28c5c4e65c0f17b280981ec905b8 404 PRINTS PR00344 Bacterial sensor protein C-terminal signature 335 349 1.6E-6 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS36010 a17d28c5c4e65c0f17b280981ec905b8 404 PRINTS PR00344 Bacterial sensor protein C-terminal signature 359 377 1.6E-6 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS36010 a17d28c5c4e65c0f17b280981ec905b8 404 PRINTS PR00344 Bacterial sensor protein C-terminal signature 383 396 1.6E-6 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS36010 a17d28c5c4e65c0f17b280981ec905b8 404 Pfam PF07730 Histidine kinase 195 261 9.9E-15 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMALA_RS36010 a17d28c5c4e65c0f17b280981ec905b8 404 SUPERFAMILY SSF55874 267 396 2.1E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS36010 a17d28c5c4e65c0f17b280981ec905b8 404 PIRSF PIRSF037434 4 403 7.7E-76 T 29-03-2018 IPR017205 Signal transduction histidine kinase, ChrS SMALA_RS36010 a17d28c5c4e65c0f17b280981ec905b8 404 SMART SM00387 299 399 5.7E-7 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS07715 6fa05bdc74aa21fb5710c59e7a795ca6 413 SUPERFAMILY SSF47413 4 70 2.82E-13 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS07715 6fa05bdc74aa21fb5710c59e7a795ca6 413 SMART SM00530 12 68 6.2E-11 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS07715 6fa05bdc74aa21fb5710c59e7a795ca6 413 Pfam PF13560 Helix-turn-helix domain 8 68 3.3E-12 T 29-03-2018 SMALA_RS07715 6fa05bdc74aa21fb5710c59e7a795ca6 413 Gene3D G3DSA:1.10.260.40 2 61 4.7E-16 T 29-03-2018 SMALA_RS07715 6fa05bdc74aa21fb5710c59e7a795ca6 413 Gene3D G3DSA:1.25.40.10 62 390 0.0039 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS38375 692f978a69e6b352311709d53992cadc 423 PRINTS PR01035 Tetracycline resistance protein signature 284 305 3.3E-15 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 SMALA_RS38375 692f978a69e6b352311709d53992cadc 423 PRINTS PR01035 Tetracycline resistance protein signature 26 42 3.3E-15 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 SMALA_RS38375 692f978a69e6b352311709d53992cadc 423 PRINTS PR01035 Tetracycline resistance protein signature 168 188 3.3E-15 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 SMALA_RS38375 692f978a69e6b352311709d53992cadc 423 PRINTS PR01035 Tetracycline resistance protein signature 140 162 3.3E-15 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 SMALA_RS38375 692f978a69e6b352311709d53992cadc 423 Gene3D G3DSA:1.20.1250.20 202 386 1.7E-18 T 29-03-2018 SMALA_RS38375 692f978a69e6b352311709d53992cadc 423 SUPERFAMILY SSF103473 4 380 2.49E-53 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS38375 692f978a69e6b352311709d53992cadc 423 Gene3D G3DSA:1.20.1250.20 13 201 2.9E-23 T 29-03-2018 SMALA_RS38375 692f978a69e6b352311709d53992cadc 423 Pfam PF07690 Major Facilitator Superfamily 21 235 6.4E-29 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS38375 692f978a69e6b352311709d53992cadc 423 Pfam PF07690 Major Facilitator Superfamily 242 377 8.4E-10 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS03165 31163f82be1cee2a1efdd028c0025751 265 Pfam PF01177 Asp/Glu/Hydantoin racemase 6 226 1.3E-6 T 29-03-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMALA_RS03165 31163f82be1cee2a1efdd028c0025751 265 Hamap MF_00943 Maleate isomerase [maiA]. 4 250 47.202 T 29-03-2018 IPR028615 Maleate isomerase GO:0050076 KEGG: 00650+5.2.1.1|KEGG: 00760+5.2.1.1|MetaCyc: PWY-5033|MetaCyc: PWY-6993|MetaCyc: PWY-7128|MetaCyc: PWY-722 SMALA_RS03165 31163f82be1cee2a1efdd028c0025751 265 PIRSF PIRSF015736 1 250 1.9E-59 T 29-03-2018 IPR026286 Maleate isomerase/Arylmalonate decarboxylase SMALA_RS03165 31163f82be1cee2a1efdd028c0025751 265 Gene3D G3DSA:3.40.50.2300 98 258 5.8E-5 T 29-03-2018 SMALA_RS02315 4cc61e0f8a18bd33fb9afeb2513bc5a1 168 SUPERFAMILY SSF46767 81 164 5.62E-30 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 SMALA_RS02315 4cc61e0f8a18bd33fb9afeb2513bc5a1 168 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 6 163 36.686 T 29-03-2018 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 SMALA_RS02315 4cc61e0f8a18bd33fb9afeb2513bc5a1 168 Gene3D G3DSA:1.10.10.10 77 165 2.6E-33 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS02315 4cc61e0f8a18bd33fb9afeb2513bc5a1 168 SUPERFAMILY SSF53155 3 87 2.59E-12 T 29-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 SMALA_RS02315 4cc61e0f8a18bd33fb9afeb2513bc5a1 168 Gene3D G3DSA:3.30.160.70 1 76 9.1E-20 T 29-03-2018 SMALA_RS02315 4cc61e0f8a18bd33fb9afeb2513bc5a1 168 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 83 163 6.7E-31 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 SMALA_RS02315 4cc61e0f8a18bd33fb9afeb2513bc5a1 168 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 82 162 9.1E-33 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 SMALA_RS07000 b99c28bdac7c85bbb5eddf9dc1a7520c 595 Gene3D G3DSA:3.40.50.1220 192 362 1.3E-51 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain SMALA_RS07000 b99c28bdac7c85bbb5eddf9dc1a7520c 595 Gene3D G3DSA:3.40.50.970 363 564 2.1E-46 T 29-03-2018 SMALA_RS07000 b99c28bdac7c85bbb5eddf9dc1a7520c 595 SUPERFAMILY SSF52518 379 580 1.11E-55 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold SMALA_RS07000 b99c28bdac7c85bbb5eddf9dc1a7520c 595 SUPERFAMILY SSF52518 3 188 2.06E-50 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold SMALA_RS07000 b99c28bdac7c85bbb5eddf9dc1a7520c 595 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 402 554 1.1E-37 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 SMALA_RS07000 b99c28bdac7c85bbb5eddf9dc1a7520c 595 SUPERFAMILY SSF52467 163 368 1.45E-53 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain SMALA_RS07000 b99c28bdac7c85bbb5eddf9dc1a7520c 595 Gene3D G3DSA:3.40.50.970 1 191 1.5E-48 T 29-03-2018 SMALA_RS07000 b99c28bdac7c85bbb5eddf9dc1a7520c 595 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 200 338 2.0E-41 T 29-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 SMALA_RS07000 b99c28bdac7c85bbb5eddf9dc1a7520c 595 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 5 179 2.1E-49 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 SMALA_RS17815 d8f8f5a980f28b5ae5af4507d4809cf0 453 Gene3D G3DSA:3.40.50.2000 50 244 2.1E-23 T 29-03-2018 SMALA_RS17815 d8f8f5a980f28b5ae5af4507d4809cf0 453 Pfam PF13439 Glycosyltransferase Family 4 55 236 4.9E-31 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 SMALA_RS17815 d8f8f5a980f28b5ae5af4507d4809cf0 453 Gene3D G3DSA:3.40.50.2000 245 422 2.2E-46 T 29-03-2018 SMALA_RS17815 d8f8f5a980f28b5ae5af4507d4809cf0 453 SUPERFAMILY SSF53756 36 442 1.52E-83 T 29-03-2018 SMALA_RS17815 d8f8f5a980f28b5ae5af4507d4809cf0 453 Pfam PF00534 Glycosyl transferases group 1 247 419 2.6E-31 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 SMALA_RS17815 d8f8f5a980f28b5ae5af4507d4809cf0 453 TIGRFAM TIGR03449 mycothiol_MshA: D-inositol-3-phosphate glycosyltransferase 36 443 6.6E-202 T 29-03-2018 IPR017814 Mycothiol biosynthesis protein, MshA GO:0008375|GO:0010125 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 SMALA_RS17815 d8f8f5a980f28b5ae5af4507d4809cf0 453 Hamap MF_01695 D-inositol-3-phosphate glycosyltransferase [mshA]. 35 446 51.726 T 29-03-2018 IPR017814 Mycothiol biosynthesis protein, MshA GO:0008375|GO:0010125 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 SMALA_RS05330 081b1dd90211b55307477f4ad78e2dbb 118 SUPERFAMILY SSF54909 2 107 1.9E-12 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel SMALA_RS05330 081b1dd90211b55307477f4ad78e2dbb 118 Gene3D G3DSA:3.30.70.100 1 108 2.3E-19 T 29-03-2018 SMALA_RS05330 081b1dd90211b55307477f4ad78e2dbb 118 Pfam PF07110 EthD domain 13 97 1.5E-10 T 29-03-2018 IPR009799 EthD domain SMALA_RS24675 538c805c078dbc359a1f6aa63bdb2c48 445 Pfam PF13638 PIN domain 15 158 5.0E-25 T 29-03-2018 IPR002716 PIN domain SMALA_RS24675 538c805c078dbc359a1f6aa63bdb2c48 445 SUPERFAMILY SSF88723 110 156 2.16E-7 T 29-03-2018 IPR029060 PIN domain-like SMALA_RS24675 538c805c078dbc359a1f6aa63bdb2c48 445 SUPERFAMILY SSF88723 14 72 2.16E-7 T 29-03-2018 IPR029060 PIN domain-like SMALA_RS24675 538c805c078dbc359a1f6aa63bdb2c48 445 SMART SM00670 13 145 2.8E-10 T 29-03-2018 IPR002716 PIN domain SMALA_RS24675 538c805c078dbc359a1f6aa63bdb2c48 445 Gene3D G3DSA:3.40.50.1010 12 191 9.4E-27 T 29-03-2018 IPR029060 PIN domain-like SMALA_RS24675 538c805c078dbc359a1f6aa63bdb2c48 445 Gene3D G3DSA:3.40.50.300 232 438 2.5E-16 T 29-03-2018 SMALA_RS24675 538c805c078dbc359a1f6aa63bdb2c48 445 Pfam PF02562 PhoH-like protein 235 440 3.0E-54 T 29-03-2018 IPR003714 PhoH-like protein GO:0005524 SMALA_RS24675 538c805c078dbc359a1f6aa63bdb2c48 445 SUPERFAMILY SSF52540 234 397 2.07E-17 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS36405 f64ce93bbf013875512151fb18316411 761 SUPERFAMILY SSF51445 46 404 1.37E-102 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS36405 f64ce93bbf013875512151fb18316411 761 Pfam PF14310 Fibronectin type III-like domain 679 750 5.5E-19 T 29-03-2018 IPR026891 Fibronectin type III-like domain SMALA_RS36405 f64ce93bbf013875512151fb18316411 761 Gene3D G3DSA:3.20.20.300 45 392 5.1E-105 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SMALA_RS36405 f64ce93bbf013875512151fb18316411 761 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 407 637 8.8E-61 T 29-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 SMALA_RS36405 f64ce93bbf013875512151fb18316411 761 SMART SM01217 679 750 1.2E-25 T 29-03-2018 IPR026891 Fibronectin type III-like domain SMALA_RS36405 f64ce93bbf013875512151fb18316411 761 SUPERFAMILY SSF52279 407 640 3.27E-58 T 29-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 SMALA_RS36405 f64ce93bbf013875512151fb18316411 761 Gene3D G3DSA:2.60.40.10 638 760 8.9E-29 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS36405 f64ce93bbf013875512151fb18316411 761 PRINTS PR00133 Glycosyl hydrolase family 3 signature 119 135 2.0E-17 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SMALA_RS36405 f64ce93bbf013875512151fb18316411 761 PRINTS PR00133 Glycosyl hydrolase family 3 signature 291 309 2.0E-17 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SMALA_RS36405 f64ce93bbf013875512151fb18316411 761 PRINTS PR00133 Glycosyl hydrolase family 3 signature 221 237 2.0E-17 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SMALA_RS36405 f64ce93bbf013875512151fb18316411 761 PRINTS PR00133 Glycosyl hydrolase family 3 signature 138 157 2.0E-17 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SMALA_RS36405 f64ce93bbf013875512151fb18316411 761 PRINTS PR00133 Glycosyl hydrolase family 3 signature 184 200 2.0E-17 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SMALA_RS36405 f64ce93bbf013875512151fb18316411 761 Gene3D G3DSA:3.40.50.1700 393 637 4.7E-82 T 29-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 SMALA_RS36405 f64ce93bbf013875512151fb18316411 761 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 59 370 1.1E-73 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SMALA_RS03400 b351b7986faaf264926acc885a590c81 556 PIRSF PIRSF000732 1 556 7.9E-171 T 29-03-2018 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 SMALA_RS03400 b351b7986faaf264926acc885a590c81 556 Pfam PF00391 PEP-utilising enzyme, mobile domain 150 221 1.3E-21 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 SMALA_RS03400 b351b7986faaf264926acc885a590c81 556 SUPERFAMILY SSF51621 251 533 3.93E-84 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SMALA_RS03400 b351b7986faaf264926acc885a590c81 556 Gene3D G3DSA:3.20.20.60 242 555 7.5E-93 T 29-03-2018 SMALA_RS03400 b351b7986faaf264926acc885a590c81 556 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 181 192 - T 29-03-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 SMALA_RS03400 b351b7986faaf264926acc885a590c81 556 SUPERFAMILY SSF52009 123 241 1.83E-30 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 SMALA_RS03400 b351b7986faaf264926acc885a590c81 556 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 5 545 1.1E-125 T 29-03-2018 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 SMALA_RS03400 b351b7986faaf264926acc885a590c81 556 Gene3D G3DSA:1.10.274.10 27 142 1.9E-23 T 29-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 SMALA_RS03400 b351b7986faaf264926acc885a590c81 556 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 431 446 5.7E-18 T 29-03-2018 SMALA_RS03400 b351b7986faaf264926acc885a590c81 556 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 448 463 5.7E-18 T 29-03-2018 SMALA_RS03400 b351b7986faaf264926acc885a590c81 556 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 285 304 5.7E-18 T 29-03-2018 SMALA_RS03400 b351b7986faaf264926acc885a590c81 556 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 484 496 5.7E-18 T 29-03-2018 SMALA_RS03400 b351b7986faaf264926acc885a590c81 556 SUPERFAMILY SSF47831 30 140 1.09E-21 T 29-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 SMALA_RS03400 b351b7986faaf264926acc885a590c81 556 Pfam PF05524 PEP-utilising enzyme, N-terminal 6 123 4.8E-22 T 29-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 SMALA_RS03400 b351b7986faaf264926acc885a590c81 556 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 253 524 5.8E-79 T 29-03-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 SMALA_RS03400 b351b7986faaf264926acc885a590c81 556 Gene3D G3DSA:3.50.30.10 145 240 9.3E-25 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 SMALA_RS03400 b351b7986faaf264926acc885a590c81 556 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 431 449 - T 29-03-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 SMALA_RS09070 3502091b7baf45db296cb6a9ae3508e2 77 Gene3D G3DSA:2.30.170.10 34 72 1.3E-4 T 29-03-2018 SMALA_RS09070 3502091b7baf45db296cb6a9ae3508e2 77 Gene3D G3DSA:2.10.110.10 1 33 0.41 T 29-03-2018 SMALA_RS15665 af2d611998024d54fb2fa6e0017299c7 229 Gene3D G3DSA:3.30.160.100 1 107 2.7E-23 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 SMALA_RS15665 af2d611998024d54fb2fa6e0017299c7 229 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 154 207 3.8E-22 T 29-03-2018 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal SMALA_RS15665 af2d611998024d54fb2fa6e0017299c7 229 Hamap MF_00839 Ribosome hibernation promoting factor [hpf]. 1 211 22.435 T 29-03-2018 IPR034694 Ribosome hibernation promoting factor, long/plastid SMALA_RS15665 af2d611998024d54fb2fa6e0017299c7 229 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 3 100 2.5E-19 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 SMALA_RS15665 af2d611998024d54fb2fa6e0017299c7 229 SUPERFAMILY SSF69754 3 108 6.02E-22 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 SMALA_RS15665 af2d611998024d54fb2fa6e0017299c7 229 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 2 104 1.1E-21 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 SMALA_RS15955 8e4e1d00fd22b10259411ccbf9da9aa1 446 PIRSF PIRSF000124 3 443 6.1E-116 T 29-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 SMALA_RS15955 8e4e1d00fd22b10259411ccbf9da9aa1 446 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 210 303 4.6E-31 T 29-03-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 SMALA_RS15955 8e4e1d00fd22b10259411ccbf9da9aa1 446 Gene3D G3DSA:1.20.5.100 210 232 8.3E-14 T 29-03-2018 SMALA_RS15955 8e4e1d00fd22b10259411ccbf9da9aa1 446 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 4 424 2.9E-125 T 29-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 SMALA_RS15955 8e4e1d00fd22b10259411ccbf9da9aa1 446 Gene3D G3DSA:3.40.50.720 1 206 6.0E-53 T 29-03-2018 SMALA_RS15955 8e4e1d00fd22b10259411ccbf9da9aa1 446 Gene3D G3DSA:3.40.50.720 233 440 1.5E-63 T 29-03-2018 SMALA_RS15955 8e4e1d00fd22b10259411ccbf9da9aa1 446 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 4 191 2.9E-57 T 29-03-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 SMALA_RS15955 8e4e1d00fd22b10259411ccbf9da9aa1 446 PIRSF PIRSF500134 3 446 6.4E-154 T 29-03-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 SMALA_RS15955 8e4e1d00fd22b10259411ccbf9da9aa1 446 SUPERFAMILY SSF51735 4 197 2.69E-47 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS15955 8e4e1d00fd22b10259411ccbf9da9aa1 446 SUPERFAMILY SSF52413 317 438 2.49E-33 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 SMALA_RS15955 8e4e1d00fd22b10259411ccbf9da9aa1 446 SUPERFAMILY SSF48179 210 308 7.99E-27 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMALA_RS15955 8e4e1d00fd22b10259411ccbf9da9aa1 446 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 327 428 3.3E-25 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 SMALA_RS15955 8e4e1d00fd22b10259411ccbf9da9aa1 446 SMART SM00984 327 428 4.0E-41 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 SMALA_RS16655 085dde044e085b4710ae8f84f5d8f1f4 211 SUPERFAMILY SSF47090 3 71 1.4E-17 T 29-03-2018 IPR002477 Peptidoglycan binding-like SMALA_RS16655 085dde044e085b4710ae8f84f5d8f1f4 211 Gene3D G3DSA:1.10.101.10 2 73 6.8E-17 T 29-03-2018 IPR002477 Peptidoglycan binding-like SMALA_RS16655 085dde044e085b4710ae8f84f5d8f1f4 211 Pfam PF03734 L,D-transpeptidase catalytic domain 98 209 2.1E-16 T 29-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 SMALA_RS16655 085dde044e085b4710ae8f84f5d8f1f4 211 Gene3D G3DSA:2.40.440.10 92 211 1.5E-22 T 29-03-2018 SMALA_RS16655 085dde044e085b4710ae8f84f5d8f1f4 211 SUPERFAMILY SSF141523 97 210 1.11E-21 T 29-03-2018 SMALA_RS16655 085dde044e085b4710ae8f84f5d8f1f4 211 Pfam PF01471 Putative peptidoglycan binding domain 11 67 4.3E-14 T 29-03-2018 IPR002477 Peptidoglycan binding-like SMALA_RS28975 8e816a932ae598c6af48616799a22121 201 SUPERFAMILY SSF54909 13 84 4.83E-7 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel SMALA_RS28975 8e816a932ae598c6af48616799a22121 201 Pfam PF16291 Domain of unknown function (DUF4937 2 86 3.0E-30 T 29-03-2018 IPR032555 Domain of unknown function DUF4937 SMALA_RS28975 8e816a932ae598c6af48616799a22121 201 Gene3D G3DSA:3.30.70.100 10 90 0.0044 T 29-03-2018 SMALA_RS28975 8e816a932ae598c6af48616799a22121 201 Gene3D G3DSA:3.30.70.100 91 185 7.2E-9 T 29-03-2018 SMALA_RS28975 8e816a932ae598c6af48616799a22121 201 SUPERFAMILY SSF54909 105 167 2.1E-5 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel SMALA_RS34710 45c4e10967484820d936d714f93d7660 305 Pfam PF00296 Luciferase-like monooxygenase 17 281 3.2E-33 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS34710 45c4e10967484820d936d714f93d7660 305 SUPERFAMILY SSF51679 4 300 1.13E-49 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS34710 45c4e10967484820d936d714f93d7660 305 Gene3D G3DSA:3.20.20.30 12 302 2.4E-53 T 29-03-2018 SMALA_RS34710 45c4e10967484820d936d714f93d7660 305 TIGRFAM TIGR03621 F420_MSMEG_2516: probable F420-dependent oxidoreductase, MSMEG_2516 family 5 302 7.4E-108 T 29-03-2018 IPR019923 Luciferase-like, F420-dependent oxidoreductase, MSMEG2516, predicted SMALA_RS17125 9a6242c8b66763c87fcc8336c6ce2f22 465 Gene3D G3DSA:1.10.260.40 2 115 4.4E-4 T 29-03-2018 SMALA_RS17125 9a6242c8b66763c87fcc8336c6ce2f22 465 Gene3D G3DSA:1.25.40.10 161 454 1.7E-13 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS17125 9a6242c8b66763c87fcc8336c6ce2f22 465 SUPERFAMILY SSF48452 226 255 3.31E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS17125 9a6242c8b66763c87fcc8336c6ce2f22 465 SUPERFAMILY SSF48452 351 427 3.31E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS20070 9a09b3288e39b6d38b07de8b5eb3cf2a 608 SUPERFAMILY SSF101898 163 473 2.56E-32 T 29-03-2018 SMALA_RS20070 9a09b3288e39b6d38b07de8b5eb3cf2a 608 Pfam PF13905 Thioredoxin-like 33 127 2.3E-12 T 29-03-2018 IPR012336 Thioredoxin-like fold SMALA_RS20070 9a09b3288e39b6d38b07de8b5eb3cf2a 608 Gene3D G3DSA:2.120.10.30 214 375 1.1E-13 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like SMALA_RS20070 9a09b3288e39b6d38b07de8b5eb3cf2a 608 SUPERFAMILY SSF52833 20 150 1.12E-29 T 29-03-2018 IPR012336 Thioredoxin-like fold SMALA_RS20070 9a09b3288e39b6d38b07de8b5eb3cf2a 608 Gene3D G3DSA:3.40.30.10 11 169 6.1E-24 T 29-03-2018 SMALA_RS20070 9a09b3288e39b6d38b07de8b5eb3cf2a 608 Gene3D G3DSA:2.120.10.30 376 550 9.2E-9 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like SMALA_RS17990 7f6fdce04775daee4bc1d3890666b3c4 265 Gene3D G3DSA:3.30.420.40 1 100 1.1E-4 T 29-03-2018 SMALA_RS17990 7f6fdce04775daee4bc1d3890666b3c4 265 Gene3D G3DSA:3.30.420.40 101 265 4.0E-60 T 29-03-2018 SMALA_RS17990 7f6fdce04775daee4bc1d3890666b3c4 265 Pfam PF03309 Type III pantothenate kinase 2 211 3.1E-70 T 29-03-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 SMALA_RS17990 7f6fdce04775daee4bc1d3890666b3c4 265 SUPERFAMILY SSF53067 1 126 7.34E-33 T 29-03-2018 SMALA_RS17990 7f6fdce04775daee4bc1d3890666b3c4 265 Hamap MF_01274 Type III pantothenate kinase [coaX]. 1 262 35.949 T 29-03-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 SMALA_RS17990 7f6fdce04775daee4bc1d3890666b3c4 265 SUPERFAMILY SSF53067 128 261 7.45E-37 T 29-03-2018 SMALA_RS17990 7f6fdce04775daee4bc1d3890666b3c4 265 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 2 258 1.8E-77 T 29-03-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 SMALA_RS09570 77d2ecedac63a2680d18e4a3d8dc68be 258 SUPERFAMILY SSF51351 4 255 1.31E-91 T 29-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMALA_RS09570 77d2ecedac63a2680d18e4a3d8dc68be 258 Pfam PF00121 Triosephosphate isomerase 7 253 4.9E-88 T 29-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMALA_RS09570 77d2ecedac63a2680d18e4a3d8dc68be 258 Gene3D G3DSA:3.20.20.70 2 258 9.0E-100 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS09570 77d2ecedac63a2680d18e4a3d8dc68be 258 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 8 247 8.0E-56 T 29-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMALA_RS09570 77d2ecedac63a2680d18e4a3d8dc68be 258 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 4 256 39.335 T 29-03-2018 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMALA_RS09570 77d2ecedac63a2680d18e4a3d8dc68be 258 ProSitePatterns PS00171 Triosephosphate isomerase active site. 171 181 - T 29-03-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMALA_RS01230 72e9196888048433c4d968993edfb6f1 537 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 14 34 0.0013 T 29-03-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal SMALA_RS01230 72e9196888048433c4d968993edfb6f1 537 Pfam PF16656 Purple acid Phosphatase, N-terminal domain 60 151 7.9E-16 T 29-03-2018 IPR015914 Purple acid phosphatase, N-terminal GO:0003993|GO:0046872 SMALA_RS01230 72e9196888048433c4d968993edfb6f1 537 Gene3D G3DSA:2.60.40.380 59 154 1.5E-15 T 29-03-2018 SMALA_RS01230 72e9196888048433c4d968993edfb6f1 537 SUPERFAMILY SSF56300 158 526 7.75E-45 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SMALA_RS01230 72e9196888048433c4d968993edfb6f1 537 SUPERFAMILY SSF49363 52 153 5.89E-21 T 29-03-2018 IPR008963 Purple acid phosphatase-like, N-terminal GO:0003993|GO:0046872 SMALA_RS01230 72e9196888048433c4d968993edfb6f1 537 Pfam PF00149 Calcineurin-like phosphoesterase 209 392 3.1E-13 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 SMALA_RS01230 72e9196888048433c4d968993edfb6f1 537 Gene3D G3DSA:3.60.21.10 155 536 1.2E-48 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SMALA_RS10410 9a5198eb53fdc94e81c727218223f56a 226 Pfam PF00072 Response regulator receiver domain 12 123 5.0E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS10410 9a5198eb53fdc94e81c727218223f56a 226 ProSitePatterns PS00622 LuxR-type HTH domain signature. 178 205 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS10410 9a5198eb53fdc94e81c727218223f56a 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 178 194 7.4E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS10410 9a5198eb53fdc94e81c727218223f56a 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 194 206 7.4E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS10410 9a5198eb53fdc94e81c727218223f56a 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 178 7.4E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS10410 9a5198eb53fdc94e81c727218223f56a 226 SUPERFAMILY SSF52172 8 128 1.71E-32 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS10410 9a5198eb53fdc94e81c727218223f56a 226 Pfam PF00196 Bacterial regulatory proteins, luxR family 163 218 8.8E-21 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS10410 9a5198eb53fdc94e81c727218223f56a 226 SUPERFAMILY SSF46894 151 223 6.46E-24 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS10410 9a5198eb53fdc94e81c727218223f56a 226 SMART SM00421 161 218 1.1E-26 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS10410 9a5198eb53fdc94e81c727218223f56a 226 Gene3D G3DSA:3.40.50.2300 1 124 8.1E-33 T 29-03-2018 SMALA_RS10410 9a5198eb53fdc94e81c727218223f56a 226 SMART SM00448 10 122 3.8E-33 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS10410 9a5198eb53fdc94e81c727218223f56a 226 Gene3D G3DSA:1.10.10.10 125 226 2.1E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS07465 25bd241be3b4257d3a4452341d8066e1 297 Pfam PF01391 Collagen triple helix repeat (20 copies) 155 209 7.3E-10 T 29-03-2018 IPR008160 Collagen triple helix repeat SMALA_RS07465 25bd241be3b4257d3a4452341d8066e1 297 Pfam PF03777 Small secreted domain (DUF320) 89 143 4.3E-17 T 29-03-2018 IPR005528 Domain of unknown function DUF320, Streptomyces species SMALA_RS07465 25bd241be3b4257d3a4452341d8066e1 297 Pfam PF03777 Small secreted domain (DUF320) 26 78 2.0E-21 T 29-03-2018 IPR005528 Domain of unknown function DUF320, Streptomyces species SMALA_RS37630 0213d6b077a806e8bc07d3657bad3458 142 Gene3D G3DSA:2.30.110.10 3 142 2.6E-28 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS37630 0213d6b077a806e8bc07d3657bad3458 142 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 14 135 1.5E-39 T 29-03-2018 IPR019920 F420-binding domain, putative SMALA_RS37630 0213d6b077a806e8bc07d3657bad3458 142 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 12 91 4.2E-18 T 29-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 SMALA_RS37630 0213d6b077a806e8bc07d3657bad3458 142 SUPERFAMILY SSF50475 3 139 2.95E-31 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS10525 8798fc69027e6b84cd97c68b8a62d1e3 351 SUPERFAMILY SSF50022 168 350 4.06E-29 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMALA_RS10525 8798fc69027e6b84cd97c68b8a62d1e3 351 PRINTS PR00162 Rieske 2Fe-2S subunit signature 272 283 7.1E-6 T 29-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 SMALA_RS10525 8798fc69027e6b84cd97c68b8a62d1e3 351 PRINTS PR00162 Rieske 2Fe-2S subunit signature 308 320 7.1E-6 T 29-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 SMALA_RS10525 8798fc69027e6b84cd97c68b8a62d1e3 351 PRINTS PR00162 Rieske 2Fe-2S subunit signature 294 306 7.1E-6 T 29-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 SMALA_RS10525 8798fc69027e6b84cd97c68b8a62d1e3 351 Pfam PF00355 Rieske [2Fe-2S] domain 238 322 2.5E-10 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMALA_RS10525 8798fc69027e6b84cd97c68b8a62d1e3 351 Gene3D G3DSA:2.102.10.10 191 351 9.4E-36 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMALA_RS15505 3dfb8ddc8aa1e93df4e9926ed9731634 159 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 10 133 9.0E-55 T 29-03-2018 IPR000037 SsrA-binding protein GO:0003723 SMALA_RS15505 3dfb8ddc8aa1e93df4e9926ed9731634 159 Hamap MF_00023 SsrA-binding protein [smpB]. 1 159 76.345 T 29-03-2018 IPR000037 SsrA-binding protein GO:0003723 SMALA_RS15505 3dfb8ddc8aa1e93df4e9926ed9731634 159 SUPERFAMILY SSF74982 3 133 3.92E-54 T 29-03-2018 IPR023620 Small protein B SMALA_RS15505 3dfb8ddc8aa1e93df4e9926ed9731634 159 ProSitePatterns PS01317 SsrA-binding protein. 28 40 - T 29-03-2018 IPR020081 SsrA-binding protein, conserved site SMALA_RS15505 3dfb8ddc8aa1e93df4e9926ed9731634 159 Pfam PF01668 SmpB protein 10 150 1.1E-62 T 29-03-2018 IPR000037 SsrA-binding protein GO:0003723 SMALA_RS15505 3dfb8ddc8aa1e93df4e9926ed9731634 159 Gene3D G3DSA:2.40.280.10 10 128 6.3E-52 T 29-03-2018 IPR023620 Small protein B SMALA_RS15505 3dfb8ddc8aa1e93df4e9926ed9731634 159 TIGRFAM TIGR00086 smpB: SsrA-binding protein 10 150 1.6E-57 T 29-03-2018 IPR000037 SsrA-binding protein GO:0003723 SMALA_RS38075 c8c55ac657a39a6846545b5154082caa 336 Pfam PF00294 pfkB family carbohydrate kinase 19 310 1.2E-47 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB SMALA_RS38075 c8c55ac657a39a6846545b5154082caa 336 Gene3D G3DSA:3.40.1190.20 17 330 3.4E-64 T 29-03-2018 IPR029056 Ribokinase-like SMALA_RS38075 c8c55ac657a39a6846545b5154082caa 336 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 266 279 - T 29-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 SMALA_RS38075 c8c55ac657a39a6846545b5154082caa 336 SUPERFAMILY SSF53613 18 321 3.12E-60 T 29-03-2018 IPR029056 Ribokinase-like SMALA_RS41275 6b8c595877e510cf577f2963c3df66b4 154 TIGRFAM TIGR00494 crcB: protein CrcB 31 144 5.2E-25 T 29-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 SMALA_RS41275 6b8c595877e510cf577f2963c3df66b4 154 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 29 146 17.935 T 29-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 SMALA_RS41275 6b8c595877e510cf577f2963c3df66b4 154 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 31 140 1.1E-22 T 29-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 SMALA_RS34210 71b9ac86e953eade153ab3b682c5ff1b 149 Gene3D G3DSA:3.30.450.30 8 135 2.4E-40 T 29-03-2018 SMALA_RS34210 71b9ac86e953eade153ab3b682c5ff1b 149 Pfam PF03259 Roadblock/LC7 domain 14 103 3.8E-21 T 29-03-2018 IPR004942 Roadblock/LAMTOR2 domain SMALA_RS34210 71b9ac86e953eade153ab3b682c5ff1b 149 SMART SM00960 13 103 3.3E-27 T 29-03-2018 IPR004942 Roadblock/LAMTOR2 domain SMALA_RS34210 71b9ac86e953eade153ab3b682c5ff1b 149 SUPERFAMILY SSF103196 8 131 2.79E-30 T 29-03-2018 SMALA_RS34735 d18f0b863033de23952401965f19920f 406 PIRSF PIRSF001619 2 329 3.5E-107 T 29-03-2018 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 SMALA_RS34735 d18f0b863033de23952401965f19920f 406 Gene3D G3DSA:3.20.20.70 14 325 6.5E-47 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS34735 d18f0b863033de23952401965f19920f 406 SMART SM00876 232 322 1.4E-34 T 29-03-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 SMALA_RS34735 d18f0b863033de23952401965f19920f 406 SUPERFAMILY SSF102114 16 321 1.2E-73 T 29-03-2018 SMALA_RS34735 d18f0b863033de23952401965f19920f 406 SMART SM00729 55 261 1.2E-32 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 SMALA_RS34735 d18f0b863033de23952401965f19920f 406 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 232 321 6.3E-15 T 29-03-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 SMALA_RS34735 d18f0b863033de23952401965f19920f 406 Hamap MF_01694 Biotin synthase [bioB]. 15 323 39.621 T 29-03-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 SMALA_RS34735 d18f0b863033de23952401965f19920f 406 Pfam PF04055 Radical SAM superfamily 65 220 7.6E-11 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 SMALA_RS34735 d18f0b863033de23952401965f19920f 406 TIGRFAM TIGR00433 bioB: biotin synthase 28 321 2.0E-113 T 29-03-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 SMALA_RS28990 e4b2adc183ae53dc09896bdd625a7a9f 219 SMART SM00855 6 166 1.9E-18 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SMALA_RS28990 e4b2adc183ae53dc09896bdd625a7a9f 219 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 7 187 1.4E-35 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SMALA_RS28990 e4b2adc183ae53dc09896bdd625a7a9f 219 SUPERFAMILY SSF53254 4 199 8.12E-41 T 29-03-2018 IPR029033 Histidine phosphatase superfamily SMALA_RS28990 e4b2adc183ae53dc09896bdd625a7a9f 219 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 9 18 - T 29-03-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 SMALA_RS28990 e4b2adc183ae53dc09896bdd625a7a9f 219 PIRSF PIRSF000709 1 186 1.5E-9 T 29-03-2018 SMALA_RS28990 e4b2adc183ae53dc09896bdd625a7a9f 219 Gene3D G3DSA:3.40.50.1240 3 209 4.4E-46 T 29-03-2018 IPR029033 Histidine phosphatase superfamily SMALA_RS05130 e3c8cf6be719991b3fd48260e80e5eef 385 Gene3D G3DSA:3.30.565.10 257 385 1.8E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS05130 e3c8cf6be719991b3fd48260e80e5eef 385 Pfam PF07730 Histidine kinase 185 249 2.6E-16 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMALA_RS05130 e3c8cf6be719991b3fd48260e80e5eef 385 SUPERFAMILY SSF55874 270 380 5.57E-14 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS41625 c73ca65e8fcd1a7ff4c257578ba053f4 300 Gene3D G3DSA:3.40.190.10 184 269 3.8E-10 T 29-03-2018 SMALA_RS41625 c73ca65e8fcd1a7ff4c257578ba053f4 300 Gene3D G3DSA:3.40.190.10 98 183 1.0E-9 T 29-03-2018 SMALA_RS41625 c73ca65e8fcd1a7ff4c257578ba053f4 300 SUPERFAMILY SSF46785 5 86 4.42E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS41625 c73ca65e8fcd1a7ff4c257578ba053f4 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 7.2E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS41625 c73ca65e8fcd1a7ff4c257578ba053f4 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 7.2E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS41625 c73ca65e8fcd1a7ff4c257578ba053f4 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 7.2E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS41625 c73ca65e8fcd1a7ff4c257578ba053f4 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 65 1.5E-14 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS41625 c73ca65e8fcd1a7ff4c257578ba053f4 300 Pfam PF03466 LysR substrate binding domain 95 295 2.2E-16 T 29-03-2018 IPR005119 LysR, substrate-binding SMALA_RS41625 c73ca65e8fcd1a7ff4c257578ba053f4 300 SUPERFAMILY SSF53850 90 296 3.08E-33 T 29-03-2018 SMALA_RS41625 c73ca65e8fcd1a7ff4c257578ba053f4 300 Gene3D G3DSA:1.10.10.10 1 91 6.0E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS28970 f90ab2b3313200021398f90bbfeec036 954 Gene3D G3DSA:3.20.70.20 49 704 2.0E-170 T 29-03-2018 SMALA_RS28970 f90ab2b3313200021398f90bbfeec036 954 SUPERFAMILY SSF51998 158 593 9.77E-132 T 29-03-2018 SMALA_RS28970 f90ab2b3313200021398f90bbfeec036 954 SUPERFAMILY SSF51998 627 701 9.77E-132 T 29-03-2018 SMALA_RS28970 f90ab2b3313200021398f90bbfeec036 954 PRINTS PR01183 Ribonucleotide reductase large chain signature 233 252 2.5E-16 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMALA_RS28970 f90ab2b3313200021398f90bbfeec036 954 PRINTS PR01183 Ribonucleotide reductase large chain signature 436 458 2.5E-16 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMALA_RS28970 f90ab2b3313200021398f90bbfeec036 954 PRINTS PR01183 Ribonucleotide reductase large chain signature 464 487 2.5E-16 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMALA_RS28970 f90ab2b3313200021398f90bbfeec036 954 PRINTS PR01183 Ribonucleotide reductase large chain signature 398 421 2.5E-16 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMALA_RS28970 f90ab2b3313200021398f90bbfeec036 954 PRINTS PR01183 Ribonucleotide reductase large chain signature 360 371 2.5E-16 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMALA_RS28970 f90ab2b3313200021398f90bbfeec036 954 PRINTS PR01183 Ribonucleotide reductase large chain signature 543 570 2.5E-16 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMALA_RS28970 f90ab2b3313200021398f90bbfeec036 954 Pfam PF08471 Class II vitamin B12-dependent ribonucleotide reductase 54 137 2.1E-19 T 29-03-2018 IPR013678 Ribonucleotide reductase class II vitamin B12-dependent, N-terminal domain GO:0004748|GO:0050897|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SMALA_RS28970 f90ab2b3313200021398f90bbfeec036 954 Pfam PF02867 Ribonucleotide reductase, barrel domain 158 697 4.3E-148 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMALA_RS28970 f90ab2b3313200021398f90bbfeec036 954 TIGRFAM TIGR02504 NrdJ_Z: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent 94 707 4.6E-188 T 29-03-2018 IPR013344 Ribonucleotide reductase, adenosylcobalamin-dependent GO:0000166|GO:0004748|GO:0031419|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SMALA_RS35520 c92f7ccb50ac2ccec5383ea99315319f 136 SUPERFAMILY SSF54106 85 133 2.62E-6 T 29-03-2018 IPR018392 LysM domain SMALA_RS35520 c92f7ccb50ac2ccec5383ea99315319f 136 SMART SM00257 85 134 2.5E-7 T 29-03-2018 IPR018392 LysM domain SMALA_RS35520 c92f7ccb50ac2ccec5383ea99315319f 136 Pfam PF01476 LysM domain 86 133 8.4E-8 T 29-03-2018 IPR018392 LysM domain SMALA_RS35520 c92f7ccb50ac2ccec5383ea99315319f 136 Gene3D G3DSA:3.10.350.10 79 135 9.7E-16 T 29-03-2018 SMALA_RS07910 bd37d6c519bbafe472ea36893422ea91 465 Gene3D G3DSA:1.10.510.10 123 335 3.8E-31 T 29-03-2018 SMALA_RS07910 bd37d6c519bbafe472ea36893422ea91 465 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 159 171 - T 29-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMALA_RS07910 bd37d6c519bbafe472ea36893422ea91 465 SUPERFAMILY SSF56112 12 281 3.14E-47 T 29-03-2018 IPR011009 Protein kinase-like domain SMALA_RS07910 bd37d6c519bbafe472ea36893422ea91 465 Gene3D G3DSA:3.30.200.20 11 122 7.3E-12 T 29-03-2018 SMALA_RS07910 bd37d6c519bbafe472ea36893422ea91 465 SMART SM00220 16 286 1.5E-21 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMALA_RS07910 bd37d6c519bbafe472ea36893422ea91 465 Pfam PF00069 Protein kinase domain 62 245 1.1E-25 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMALA_RS12375 4e57bd5c7e4a3fa12831ef9b01d154af 277 Pfam PF01903 CbiX 36 132 2.8E-20 T 29-03-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 SMALA_RS12375 4e57bd5c7e4a3fa12831ef9b01d154af 277 Pfam PF01903 CbiX 164 255 2.8E-9 T 29-03-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 SMALA_RS12375 4e57bd5c7e4a3fa12831ef9b01d154af 277 Gene3D G3DSA:3.40.50.1400 27 135 5.7E-29 T 29-03-2018 SMALA_RS12375 4e57bd5c7e4a3fa12831ef9b01d154af 277 SUPERFAMILY SSF53800 31 263 3.49E-36 T 29-03-2018 SMALA_RS12375 4e57bd5c7e4a3fa12831ef9b01d154af 277 Gene3D G3DSA:3.40.50.1400 136 272 8.4E-31 T 29-03-2018 SMALA_RS11595 5b15706fe2e4b92eb7a183343ffc69bc 244 SUPERFAMILY SSF52172 15 196 1.57E-39 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS11595 5b15706fe2e4b92eb7a183343ffc69bc 244 SMART SM00448 17 129 4.7E-39 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS11595 5b15706fe2e4b92eb7a183343ffc69bc 244 Gene3D G3DSA:1.10.10.10 138 242 5.1E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS11595 5b15706fe2e4b92eb7a183343ffc69bc 244 SMART SM00862 163 238 9.3E-21 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS11595 5b15706fe2e4b92eb7a183343ffc69bc 244 Pfam PF00072 Response regulator receiver domain 19 129 1.8E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS11595 5b15706fe2e4b92eb7a183343ffc69bc 244 Pfam PF00486 Transcriptional regulatory protein, C terminal 165 237 5.6E-19 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS11595 5b15706fe2e4b92eb7a183343ffc69bc 244 Gene3D G3DSA:3.40.50.2300 2 137 7.4E-36 T 29-03-2018 SMALA_RS19540 2f30121c2d053226c3741a860826940b 143 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 8.6E-9 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS19540 2f30121c2d053226c3741a860826940b 143 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 8.6E-9 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS19540 2f30121c2d053226c3741a860826940b 143 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 8.6E-9 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS19540 2f30121c2d053226c3741a860826940b 143 Gene3D G3DSA:1.10.1660.10 1 54 1.7E-25 T 29-03-2018 SMALA_RS19540 2f30121c2d053226c3741a860826940b 143 Pfam PF13411 MerR HTH family regulatory protein 1 61 6.9E-20 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS19540 2f30121c2d053226c3741a860826940b 143 Gene3D G3DSA:1.10.1660.10 55 140 2.5E-15 T 29-03-2018 SMALA_RS19540 2f30121c2d053226c3741a860826940b 143 SUPERFAMILY SSF46955 1 115 1.83E-29 T 29-03-2018 IPR009061 Putative DNA-binding domain SMALA_RS19540 2f30121c2d053226c3741a860826940b 143 SMART SM00422 1 69 8.5E-25 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS23570 5b603a3f4d7171a041185a5a06e2c190 348 Gene3D G3DSA:3.90.180.10 2 150 2.5E-35 T 29-03-2018 SMALA_RS23570 5b603a3f4d7171a041185a5a06e2c190 348 SUPERFAMILY SSF51735 125 267 1.64E-36 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS23570 5b603a3f4d7171a041185a5a06e2c190 348 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 36 95 3.5E-7 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS23570 5b603a3f4d7171a041185a5a06e2c190 348 SMART SM00829 16 344 7.3E-15 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS23570 5b603a3f4d7171a041185a5a06e2c190 348 SUPERFAMILY SSF50129 19 157 6.85E-27 T 29-03-2018 IPR011032 GroES-like SMALA_RS23570 5b603a3f4d7171a041185a5a06e2c190 348 Pfam PF00107 Zinc-binding dehydrogenase 160 250 4.9E-22 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMALA_RS23570 5b603a3f4d7171a041185a5a06e2c190 348 Gene3D G3DSA:3.90.180.10 272 346 3.3E-6 T 29-03-2018 SMALA_RS23570 5b603a3f4d7171a041185a5a06e2c190 348 Gene3D G3DSA:3.40.50.720 151 265 8.3E-26 T 29-03-2018 SMALA_RS02200 6213b8c68199247084cf7ab598a9c739 203 SUPERFAMILY SSF49879 102 195 3.44E-16 T 29-03-2018 IPR008984 SMAD/FHA domain GO:0005515 SMALA_RS02200 6213b8c68199247084cf7ab598a9c739 203 Gene3D G3DSA:2.60.200.20 12 196 6.9E-16 T 29-03-2018 SMALA_RS02200 6213b8c68199247084cf7ab598a9c739 203 Pfam PF00498 FHA domain 113 186 8.9E-10 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 SMALA_RS16000 265e52dc37309b2235a34c3739988601 352 Gene3D G3DSA:2.60.40.10 177 249 0.0046 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS16000 265e52dc37309b2235a34c3739988601 352 SUPERFAMILY SSF49319 41 134 1.02E-5 T 29-03-2018 IPR027273 Neocarzinostatin-like SMALA_RS16000 265e52dc37309b2235a34c3739988601 352 Gene3D G3DSA:2.60.40.230 40 142 1.5E-10 T 29-03-2018 SMALA_RS37660 e5ef036fd8d52f99a1e68595b049d974 593 Pfam PF00005 ABC transporter 372 521 6.7E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS37660 e5ef036fd8d52f99a1e68595b049d974 593 SUPERFAMILY SSF90123 34 342 1.44E-49 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMALA_RS37660 e5ef036fd8d52f99a1e68595b049d974 593 Pfam PF00664 ABC transporter transmembrane region 44 313 1.4E-26 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMALA_RS37660 e5ef036fd8d52f99a1e68595b049d974 593 Gene3D G3DSA:1.20.1560.10 24 347 3.9E-42 T 29-03-2018 SMALA_RS37660 e5ef036fd8d52f99a1e68595b049d974 593 SUPERFAMILY SSF52540 352 591 5.86E-68 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS37660 e5ef036fd8d52f99a1e68595b049d974 593 Gene3D G3DSA:3.40.50.300 348 593 4.3E-56 T 29-03-2018 SMALA_RS37660 e5ef036fd8d52f99a1e68595b049d974 593 SMART SM00382 381 567 7.5E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS07100 56384f8e6bc1864971689f39b149ac6e 491 Gene3D G3DSA:1.10.150.130 84 195 5.0E-21 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal SMALA_RS07100 56384f8e6bc1864971689f39b149ac6e 491 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 89 143 1.5E-6 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 SMALA_RS07100 56384f8e6bc1864971689f39b149ac6e 491 Gene3D G3DSA:1.10.443.10 196 399 1.4E-39 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 SMALA_RS07100 56384f8e6bc1864971689f39b149ac6e 491 Pfam PF00589 Phage integrase family 197 383 2.3E-24 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 SMALA_RS07100 56384f8e6bc1864971689f39b149ac6e 491 SUPERFAMILY SSF56349 89 390 9.71E-62 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 SMALA_RS01475 a4284367754656232c44eed8d3d4d55a 709 TIGRFAM TIGR03796 NHLM_micro_ABC1: NHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein 1 707 4.1E-298 T 29-03-2018 IPR022514 NHPM bacteriocin system ABC transporter, peptidase/ATP-binding protein SMALA_RS01475 a4284367754656232c44eed8d3d4d55a 709 Pfam PF03412 Peptidase C39 family 1 130 2.5E-37 T 29-03-2018 IPR005074 Peptidase C39, bacteriocin processing GO:0005524|GO:0006508|GO:0008233|GO:0016021 SMALA_RS01475 a4284367754656232c44eed8d3d4d55a 709 Pfam PF00664 ABC transporter transmembrane region 157 425 6.2E-24 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMALA_RS01475 a4284367754656232c44eed8d3d4d55a 709 Gene3D G3DSA:3.90.70.10 2 136 6.3E-39 T 29-03-2018 SMALA_RS01475 a4284367754656232c44eed8d3d4d55a 709 SUPERFAMILY SSF90123 147 461 3.4E-46 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMALA_RS01475 a4284367754656232c44eed8d3d4d55a 709 ProSitePatterns PS00211 ABC transporters family signature. 613 627 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS01475 a4284367754656232c44eed8d3d4d55a 709 Pfam PF00005 ABC transporter 491 641 4.0E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS01475 a4284367754656232c44eed8d3d4d55a 709 SMART SM00382 500 685 3.0E-18 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS01475 a4284367754656232c44eed8d3d4d55a 709 SUPERFAMILY SSF52540 467 707 2.71E-72 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS01475 a4284367754656232c44eed8d3d4d55a 709 Gene3D G3DSA:3.40.50.300 471 706 1.9E-62 T 29-03-2018 SMALA_RS01475 a4284367754656232c44eed8d3d4d55a 709 Gene3D G3DSA:1.20.1560.10 147 452 1.1E-32 T 29-03-2018 SMALA_RS18155 743bd2e1e8420d4598e101ca3fa2e1d1 252 SUPERFAMILY SSF89082 160 251 9.29E-31 T 29-03-2018 IPR012925 TipAS antibiotic-recognition domain SMALA_RS18155 743bd2e1e8420d4598e101ca3fa2e1d1 252 Gene3D G3DSA:1.10.1660.10 1 159 6.2E-37 T 29-03-2018 SMALA_RS18155 743bd2e1e8420d4598e101ca3fa2e1d1 252 SUPERFAMILY SSF46955 3 103 1.14E-28 T 29-03-2018 IPR009061 Putative DNA-binding domain SMALA_RS18155 743bd2e1e8420d4598e101ca3fa2e1d1 252 Pfam PF07739 TipAS antibiotic-recognition domain 131 246 6.5E-42 T 29-03-2018 IPR012925 TipAS antibiotic-recognition domain SMALA_RS18155 743bd2e1e8420d4598e101ca3fa2e1d1 252 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 39 59 2.3E-9 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS18155 743bd2e1e8420d4598e101ca3fa2e1d1 252 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 4 15 2.3E-9 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS18155 743bd2e1e8420d4598e101ca3fa2e1d1 252 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 15 28 2.3E-9 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS18155 743bd2e1e8420d4598e101ca3fa2e1d1 252 SMART SM00422 3 72 9.1E-31 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS18155 743bd2e1e8420d4598e101ca3fa2e1d1 252 Gene3D G3DSA:1.10.490.50 161 251 3.9E-32 T 29-03-2018 SMALA_RS18155 743bd2e1e8420d4598e101ca3fa2e1d1 252 ProSitePatterns PS00552 MerR-type HTH domain signature. 6 28 - T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS18155 743bd2e1e8420d4598e101ca3fa2e1d1 252 Pfam PF13411 MerR HTH family regulatory protein 3 70 1.2E-15 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS33525 475cd035129d102adf57cf697d96416e 289 SUPERFAMILY SSF54211 1 157 2.88E-16 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SMALA_RS33525 475cd035129d102adf57cf697d96416e 289 Pfam PF00288 GHMP kinases N terminal domain 77 109 9.1E-7 T 29-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 SMALA_RS33525 475cd035129d102adf57cf697d96416e 289 PIRSF PIRSF033887 1 283 6.3E-96 T 29-03-2018 IPR012363 Propanediol utilisation/coumermycin biosynthesis, PduX-related KEGG: 00040+2.7.1.17|KEGG: 00860+2.7.1.177|MetaCyc: PWY-5443 SMALA_RS33525 475cd035129d102adf57cf697d96416e 289 Pfam PF08544 GHMP kinases C terminal 194 256 2.6E-5 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain SMALA_RS33525 475cd035129d102adf57cf697d96416e 289 Gene3D G3DSA:3.10.450.50 177 279 5.2E-4 T 29-03-2018 SMALA_RS33525 475cd035129d102adf57cf697d96416e 289 Gene3D G3DSA:3.30.230.10 16 147 5.7E-12 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SMALA_RS24525 79d45469cbcb5d08cd15e51dc43a6de8 458 Pfam PF12730 ABC-2 family transporter protein 30 161 3.5E-6 T 29-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 SMALA_RS37435 1c7e5b731b75915fd40af37e8ca15576 353 SUPERFAMILY SSF56042 173 349 9.27E-47 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain SMALA_RS37435 1c7e5b731b75915fd40af37e8ca15576 353 Gene3D G3DSA:3.30.1330.10 34 171 3.9E-19 T 29-03-2018 IPR016188 PurM-like, N-terminal domain SMALA_RS37435 1c7e5b731b75915fd40af37e8ca15576 353 Pfam PF00586 AIR synthase related protein, N-terminal domain 59 167 3.1E-13 T 29-03-2018 IPR016188 PurM-like, N-terminal domain SMALA_RS37435 1c7e5b731b75915fd40af37e8ca15576 353 TIGRFAM TIGR02124 hypE: hydrogenase expression/formation protein HypE 23 353 6.9E-130 T 29-03-2018 IPR011854 Hydrogenase expression/formation protein HypE SMALA_RS37435 1c7e5b731b75915fd40af37e8ca15576 353 SUPERFAMILY SSF55326 25 170 2.27E-26 T 29-03-2018 IPR016188 PurM-like, N-terminal domain SMALA_RS37435 1c7e5b731b75915fd40af37e8ca15576 353 Gene3D G3DSA:3.90.650.10 173 341 3.5E-42 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain SMALA_RS37435 1c7e5b731b75915fd40af37e8ca15576 353 Pfam PF02769 AIR synthase related protein, C-terminal domain 179 325 3.5E-27 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain SMALA_RS37435 1c7e5b731b75915fd40af37e8ca15576 353 PIRSF PIRSF005644 18 353 8.6E-120 T 29-03-2018 IPR011854 Hydrogenase expression/formation protein HypE SMALA_RS30025 33f0570938448762e931f3a0e8dd4101 135 Gene3D G3DSA:2.170.150.20 1 135 5.6E-58 T 29-03-2018 SMALA_RS30025 33f0570938448762e931f3a0e8dd4101 135 SUPERFAMILY SSF51316 6 133 7.32E-56 T 29-03-2018 IPR011057 Mss4-like SMALA_RS30025 33f0570938448762e931f3a0e8dd4101 135 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 8 132 1.7E-48 T 29-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 SMALA_RS30025 33f0570938448762e931f3a0e8dd4101 135 Pfam PF01641 SelR domain 11 131 1.4E-53 T 29-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 SMALA_RS12475 666922c11b6aa4bb459aa27b45f600dd 347 Gene3D G3DSA:1.10.10.60 2 30 5.3E-4 T 29-03-2018 SMALA_RS12475 666922c11b6aa4bb459aa27b45f600dd 347 SUPERFAMILY SSF53822 73 344 3.73E-82 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SMALA_RS12475 666922c11b6aa4bb459aa27b45f600dd 347 Pfam PF00356 Bacterial regulatory proteins, lacI family 17 60 6.9E-13 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS12475 666922c11b6aa4bb459aa27b45f600dd 347 Gene3D G3DSA:3.40.50.2300 179 344 1.9E-54 T 29-03-2018 SMALA_RS12475 666922c11b6aa4bb459aa27b45f600dd 347 Gene3D G3DSA:3.40.50.2300 72 178 8.1E-24 T 29-03-2018 SMALA_RS12475 666922c11b6aa4bb459aa27b45f600dd 347 SMART SM00354 15 82 7.5E-12 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS12475 666922c11b6aa4bb459aa27b45f600dd 347 Gene3D G3DSA:1.10.260.40 31 71 1.0E-17 T 29-03-2018 SMALA_RS12475 666922c11b6aa4bb459aa27b45f600dd 347 Pfam PF13377 Periplasmic binding protein-like domain 180 341 1.7E-43 T 29-03-2018 SMALA_RS12475 666922c11b6aa4bb459aa27b45f600dd 347 SUPERFAMILY SSF47413 15 65 2.16E-12 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS10215 27f0886e89a1967348002c69afd41c97 364 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 188 348 1.4E-38 T 29-03-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 SMALA_RS10215 27f0886e89a1967348002c69afd41c97 364 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 3 358 31.62 T 29-03-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 SMALA_RS10215 27f0886e89a1967348002c69afd41c97 364 SUPERFAMILY SSF53756 2 358 2.9E-100 T 29-03-2018 SMALA_RS10215 27f0886e89a1967348002c69afd41c97 364 Gene3D G3DSA:3.40.50.2000 1 176 1.0E-37 T 29-03-2018 SMALA_RS10215 27f0886e89a1967348002c69afd41c97 364 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 2 351 9.0E-86 T 29-03-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 SMALA_RS10215 27f0886e89a1967348002c69afd41c97 364 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 3 142 2.3E-42 T 29-03-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 SMALA_RS10215 27f0886e89a1967348002c69afd41c97 364 Gene3D G3DSA:3.40.50.2000 177 342 1.7E-31 T 29-03-2018 SMALA_RS19185 5b00bcb462ef63be7d63480f9b4b47b8 176 SUPERFAMILY SSF88946 17 105 4.71E-13 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS19185 5b00bcb462ef63be7d63480f9b4b47b8 176 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 16 171 2.5E-61 T 29-03-2018 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 SMALA_RS19185 5b00bcb462ef63be7d63480f9b4b47b8 176 Gene3D G3DSA:1.10.1740.10 11 89 2.1E-10 T 29-03-2018 SMALA_RS19185 5b00bcb462ef63be7d63480f9b4b47b8 176 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 26 168 2.8E-22 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS19185 5b00bcb462ef63be7d63480f9b4b47b8 176 SUPERFAMILY SSF88659 106 168 9.91E-17 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS19185 5b00bcb462ef63be7d63480f9b4b47b8 176 Pfam PF08281 Sigma-70, region 4 113 166 2.1E-18 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS19185 5b00bcb462ef63be7d63480f9b4b47b8 176 Pfam PF04542 Sigma-70 region 2 22 86 8.5E-8 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS19185 5b00bcb462ef63be7d63480f9b4b47b8 176 Gene3D G3DSA:1.10.10.10 92 170 2.8E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS18025 0f53b085f02629a18bfc43092aa31595 383 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 253 326 1.1E-8 T 29-03-2018 IPR010095 Transposase IS605, OrfB, C-terminal SMALA_RS18025 0f53b085f02629a18bfc43092aa31595 383 Pfam PF01385 Probable transposase 185 283 3.5E-21 T 29-03-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 SMALA_RS18025 0f53b085f02629a18bfc43092aa31595 383 Pfam PF12323 Helix-turn-helix domain 1 43 4.4E-16 T 29-03-2018 IPR021027 Transposase, putative, helix-turn-helix domain SMALA_RS18025 0f53b085f02629a18bfc43092aa31595 383 Pfam PF07282 Putative transposase DNA-binding domain 299 369 3.6E-14 T 29-03-2018 IPR010095 Transposase IS605, OrfB, C-terminal SMALA_RS06985 ae47199a41b27f79493792b2d294b69b 284 Gene3D G3DSA:3.40.50.1820 9 262 1.7E-14 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS06985 ae47199a41b27f79493792b2d294b69b 284 SUPERFAMILY SSF53474 9 279 5.42E-34 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS06985 ae47199a41b27f79493792b2d294b69b 284 Pfam PF00756 Putative esterase 135 195 1.7E-8 T 29-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 SMALA_RS06985 ae47199a41b27f79493792b2d294b69b 284 Pfam PF00756 Putative esterase 22 112 2.3E-5 T 29-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 SMALA_RS21940 1209d0d900efca92795ca5ead5958d67 438 Gene3D G3DSA:3.90.1150.10 321 435 9.0E-17 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS21940 1209d0d900efca92795ca5ead5958d67 438 Gene3D G3DSA:3.40.640.10 177 320 6.5E-42 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS21940 1209d0d900efca92795ca5ead5958d67 438 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 13 426 1.4E-179 T 29-03-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 SMALA_RS21940 1209d0d900efca92795ca5ead5958d67 438 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 12 433 97.059 T 29-03-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 SMALA_RS21940 1209d0d900efca92795ca5ead5958d67 438 SUPERFAMILY SSF53383 11 429 1.27E-117 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS21940 1209d0d900efca92795ca5ead5958d67 438 Pfam PF00202 Aminotransferase class-III 42 426 7.0E-83 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMALA_RS21940 1209d0d900efca92795ca5ead5958d67 438 Gene3D G3DSA:3.90.1150.10 8 176 6.6E-43 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS21940 1209d0d900efca92795ca5ead5958d67 438 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 243 279 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMALA_RS00410 7cab71a0228bf37fa05779889bf5bf5e 1107 Gene3D G3DSA:3.40.50.980 477 631 6.7E-43 T 29-03-2018 SMALA_RS00410 7cab71a0228bf37fa05779889bf5bf5e 1107 SUPERFAMILY SSF56801 438 1003 4.58E-148 T 29-03-2018 SMALA_RS00410 7cab71a0228bf37fa05779889bf5bf5e 1107 SUPERFAMILY SSF52777 26 198 7.56E-42 T 29-03-2018 SMALA_RS00410 7cab71a0228bf37fa05779889bf5bf5e 1107 SUPERFAMILY SSF47336 983 1056 3.66E-16 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS00410 7cab71a0228bf37fa05779889bf5bf5e 1107 Gene3D G3DSA:2.30.38.10 788 872 1.4E-24 T 29-03-2018 SMALA_RS00410 7cab71a0228bf37fa05779889bf5bf5e 1107 Pfam PF00501 AMP-binding enzyme 482 879 9.5E-98 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS00410 7cab71a0228bf37fa05779889bf5bf5e 1107 SMART SM00823 Phosphopantetheine attachment site 990 1059 3.5E-4 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS00410 7cab71a0228bf37fa05779889bf5bf5e 1107 Gene3D G3DSA:3.30.300.30 874 995 6.3E-34 T 29-03-2018 SMALA_RS00410 7cab71a0228bf37fa05779889bf5bf5e 1107 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 503 903 7.8E-132 T 29-03-2018 IPR010071 Amino acid adenylation domain SMALA_RS00410 7cab71a0228bf37fa05779889bf5bf5e 1107 Pfam PF00668 Condensation domain 28 460 7.9E-66 T 29-03-2018 IPR001242 Condensation domain SMALA_RS00410 7cab71a0228bf37fa05779889bf5bf5e 1107 Pfam PF13193 AMP-binding enzyme C-terminal domain 887 962 2.6E-11 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS00410 7cab71a0228bf37fa05779889bf5bf5e 1107 ProSitePatterns PS00455 Putative AMP-binding domain signature. 630 641 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS00410 7cab71a0228bf37fa05779889bf5bf5e 1107 Gene3D G3DSA:1.10.1200.10 996 1093 3.7E-24 T 29-03-2018 SMALA_RS00410 7cab71a0228bf37fa05779889bf5bf5e 1107 Gene3D G3DSA:3.30.559.10 4 203 6.1E-34 T 29-03-2018 SMALA_RS00410 7cab71a0228bf37fa05779889bf5bf5e 1107 Gene3D G3DSA:3.40.50.980 632 781 1.8E-34 T 29-03-2018 SMALA_RS00410 7cab71a0228bf37fa05779889bf5bf5e 1107 SUPERFAMILY SSF52777 205 448 1.0E-49 T 29-03-2018 SMALA_RS00410 7cab71a0228bf37fa05779889bf5bf5e 1107 Pfam PF00550 Phosphopantetheine attachment site 992 1055 2.2E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS11000 66619391993abab79ab540a20bbfebee 181 Gene3D G3DSA:3.90.1570.10 1 175 2.3E-18 T 29-03-2018 SMALA_RS11000 66619391993abab79ab540a20bbfebee 181 Pfam PF05685 Putative restriction endonuclease 18 164 2.9E-17 T 29-03-2018 IPR008538 Domain of unknown function DUF820 SMALA_RS11000 66619391993abab79ab540a20bbfebee 181 SUPERFAMILY SSF52980 34 153 6.43E-10 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 SMALA_RS28725 1d5fab1d9c0eee0cb000a576cf36b75b 1849 Gene3D G3DSA:1.10.287.130 1359 1420 8.8E-17 T 29-03-2018 SMALA_RS28725 1d5fab1d9c0eee0cb000a576cf36b75b 1849 Gene3D G3DSA:3.30.450.40 1075 1276 2.1E-21 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS28725 1d5fab1d9c0eee0cb000a576cf36b75b 1849 Pfam PF00512 His Kinase A (phospho-acceptor) domain 1357 1424 4.5E-18 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS28725 1d5fab1d9c0eee0cb000a576cf36b75b 1849 SUPERFAMILY SSF58104 884 1015 1.44E-10 T 29-03-2018 SMALA_RS28725 1d5fab1d9c0eee0cb000a576cf36b75b 1849 Pfam PF00672 HAMP domain 314 360 2.3E-8 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMALA_RS28725 1d5fab1d9c0eee0cb000a576cf36b75b 1849 SUPERFAMILY SSF58104 700 880 1.91E-14 T 29-03-2018 SMALA_RS28725 1d5fab1d9c0eee0cb000a576cf36b75b 1849 SMART SM00065 1124 1281 2.6E-7 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS28725 1d5fab1d9c0eee0cb000a576cf36b75b 1849 SMART SM00448 1728 1842 3.1E-35 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS28725 1d5fab1d9c0eee0cb000a576cf36b75b 1849 SUPERFAMILY SSF58104 424 603 5.23E-10 T 29-03-2018 SMALA_RS28725 1d5fab1d9c0eee0cb000a576cf36b75b 1849 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 1471 1603 5.3E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS28725 1d5fab1d9c0eee0cb000a576cf36b75b 1849 SUPERFAMILY SSF158472 1050 1098 1.16E-5 T 29-03-2018 SMALA_RS28725 1d5fab1d9c0eee0cb000a576cf36b75b 1849 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1564 1582 1.7E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS28725 1d5fab1d9c0eee0cb000a576cf36b75b 1849 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1588 1601 1.7E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS28725 1d5fab1d9c0eee0cb000a576cf36b75b 1849 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1529 1543 1.7E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS28725 1d5fab1d9c0eee0cb000a576cf36b75b 1849 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1547 1557 1.7E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS28725 1d5fab1d9c0eee0cb000a576cf36b75b 1849 Pfam PF13185 GAF domain 1123 1269 8.6E-16 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS28725 1d5fab1d9c0eee0cb000a576cf36b75b 1849 Gene3D G3DSA:1.10.287.620 1277 1358 0.0039 T 29-03-2018 SMALA_RS28725 1d5fab1d9c0eee0cb000a576cf36b75b 1849 SUPERFAMILY SSF58104 157 328 2.48E-8 T 29-03-2018 SMALA_RS28725 1d5fab1d9c0eee0cb000a576cf36b75b 1849 SMART SM00387 1471 1604 6.7E-37 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS28725 1d5fab1d9c0eee0cb000a576cf36b75b 1849 SMART SM00304 312 364 5.1E-11 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMALA_RS28725 1d5fab1d9c0eee0cb000a576cf36b75b 1849 SMART SM00304 1048 1100 4.4E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMALA_RS28725 1d5fab1d9c0eee0cb000a576cf36b75b 1849 SMART SM00304 496 548 5.0E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMALA_RS28725 1d5fab1d9c0eee0cb000a576cf36b75b 1849 SMART SM00304 26 78 0.3 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMALA_RS28725 1d5fab1d9c0eee0cb000a576cf36b75b 1849 SMART SM00304 772 824 5.1E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMALA_RS28725 1d5fab1d9c0eee0cb000a576cf36b75b 1849 SMART SM00304 118 180 0.0073 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMALA_RS28725 1d5fab1d9c0eee0cb000a576cf36b75b 1849 SMART SM00304 956 1008 7.2E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMALA_RS28725 1d5fab1d9c0eee0cb000a576cf36b75b 1849 SMART SM00304 864 916 1.7E-7 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMALA_RS28725 1d5fab1d9c0eee0cb000a576cf36b75b 1849 SMART SM00304 680 732 6.2E-11 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMALA_RS28725 1d5fab1d9c0eee0cb000a576cf36b75b 1849 SMART SM00304 404 456 5.4E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMALA_RS28725 1d5fab1d9c0eee0cb000a576cf36b75b 1849 SMART SM00304 220 272 1.8E-7 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMALA_RS28725 1d5fab1d9c0eee0cb000a576cf36b75b 1849 SMART SM00304 588 640 4.1E-10 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMALA_RS28725 1d5fab1d9c0eee0cb000a576cf36b75b 1849 Gene3D G3DSA:2.60.120.260 232 322 5.6E-22 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS28725 1d5fab1d9c0eee0cb000a576cf36b75b 1849 Gene3D G3DSA:2.60.120.260 876 966 3.2E-20 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS28725 1d5fab1d9c0eee0cb000a576cf36b75b 1849 Gene3D G3DSA:2.60.120.260 507 598 3.5E-23 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS28725 1d5fab1d9c0eee0cb000a576cf36b75b 1849 Gene3D G3DSA:2.60.120.260 692 783 8.7E-25 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS28725 1d5fab1d9c0eee0cb000a576cf36b75b 1849 Gene3D G3DSA:2.60.120.260 599 691 7.1E-24 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS28725 1d5fab1d9c0eee0cb000a576cf36b75b 1849 Gene3D G3DSA:2.60.120.260 323 415 6.8E-20 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS28725 1d5fab1d9c0eee0cb000a576cf36b75b 1849 Gene3D G3DSA:2.60.120.260 123 231 3.2E-17 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS28725 1d5fab1d9c0eee0cb000a576cf36b75b 1849 Gene3D G3DSA:2.60.120.260 784 875 4.3E-22 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS28725 1d5fab1d9c0eee0cb000a576cf36b75b 1849 Gene3D G3DSA:2.60.120.260 416 506 3.1E-19 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS28725 1d5fab1d9c0eee0cb000a576cf36b75b 1849 Gene3D G3DSA:2.60.120.260 967 1060 2.2E-23 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS28725 1d5fab1d9c0eee0cb000a576cf36b75b 1849 SUPERFAMILY SSF58104 608 699 2.54E-6 T 29-03-2018 SMALA_RS28725 1d5fab1d9c0eee0cb000a576cf36b75b 1849 Pfam PF00072 Response regulator receiver domain 1730 1841 2.4E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS28725 1d5fab1d9c0eee0cb000a576cf36b75b 1849 SUPERFAMILY SSF55781 1088 1271 2.59E-25 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS28725 1d5fab1d9c0eee0cb000a576cf36b75b 1849 SUPERFAMILY SSF52172 1726 1847 6.4E-36 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS28725 1d5fab1d9c0eee0cb000a576cf36b75b 1849 SUPERFAMILY SSF47384 1342 1426 5.1E-21 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS28725 1d5fab1d9c0eee0cb000a576cf36b75b 1849 Gene3D G3DSA:3.40.50.2300 1726 1849 2.6E-36 T 29-03-2018 SMALA_RS28725 1d5fab1d9c0eee0cb000a576cf36b75b 1849 Gene3D G3DSA:3.30.565.10 1428 1609 1.9E-46 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS28725 1d5fab1d9c0eee0cb000a576cf36b75b 1849 SUPERFAMILY SSF55874 1413 1606 5.37E-45 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS28725 1d5fab1d9c0eee0cb000a576cf36b75b 1849 SMART SM00388 1356 1424 1.2E-23 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS28725 1d5fab1d9c0eee0cb000a576cf36b75b 1849 SUPERFAMILY SSF58104 332 465 2.88E-10 T 29-03-2018 SMALA_RS35190 9c5f30336a826259fa66807c32f3dd49 1545 SUPERFAMILY SSF49899 628 815 7.57E-28 T 29-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain SMALA_RS35190 9c5f30336a826259fa66807c32f3dd49 1545 Gene3D G3DSA:2.60.120.200 648 838 3.1E-26 T 29-03-2018 SMALA_RS35190 9c5f30336a826259fa66807c32f3dd49 1545 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 390 623 4.4E-68 T 29-03-2018 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 SMALA_RS35190 9c5f30336a826259fa66807c32f3dd49 1545 SUPERFAMILY SSF49303 275 388 1.76E-21 T 29-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 SMALA_RS35190 9c5f30336a826259fa66807c32f3dd49 1545 Gene3D G3DSA:2.60.40.10 1288 1388 6.0E-10 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS35190 9c5f30336a826259fa66807c32f3dd49 1545 Pfam PF02929 Beta galactosidase small chain 997 1263 2.1E-60 T 29-03-2018 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 SMALA_RS35190 9c5f30336a826259fa66807c32f3dd49 1545 SUPERFAMILY SSF49785 63 273 1.01E-54 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS35190 9c5f30336a826259fa66807c32f3dd49 1545 SMART SM01038 995 1264 2.9E-71 T 29-03-2018 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 SMALA_RS35190 9c5f30336a826259fa66807c32f3dd49 1545 SMART SM00560 677 811 3.8E-26 T 29-03-2018 IPR006558 LamG-like jellyroll fold SMALA_RS35190 9c5f30336a826259fa66807c32f3dd49 1545 Gene3D G3DSA:2.60.120.260 55 273 4.0E-59 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS35190 9c5f30336a826259fa66807c32f3dd49 1545 Gene3D G3DSA:3.20.20.80 381 647 5.4E-54 T 29-03-2018 SMALA_RS35190 9c5f30336a826259fa66807c32f3dd49 1545 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 661 813 2.2E-23 T 29-03-2018 SMALA_RS35190 9c5f30336a826259fa66807c32f3dd49 1545 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 102 273 3.4E-39 T 29-03-2018 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 SMALA_RS35190 9c5f30336a826259fa66807c32f3dd49 1545 SUPERFAMILY SSF51445 390 624 1.5E-66 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS35190 9c5f30336a826259fa66807c32f3dd49 1545 SUPERFAMILY SSF49303 866 970 3.17E-21 T 29-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 SMALA_RS35190 9c5f30336a826259fa66807c32f3dd49 1545 Pfam PF08305 NPCBM/NEW2 domain 1397 1537 8.8E-46 T 29-03-2018 IPR013222 Glycosyl hydrolase family 98, putative carbohydrate-binding module SMALA_RS35190 9c5f30336a826259fa66807c32f3dd49 1545 Gene3D G3DSA:2.60.40.10 275 380 1.8E-21 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS35190 9c5f30336a826259fa66807c32f3dd49 1545 SMART SM00776 1394 1539 2.9E-60 T 29-03-2018 IPR013222 Glycosyl hydrolase family 98, putative carbohydrate-binding module SMALA_RS35190 9c5f30336a826259fa66807c32f3dd49 1545 SUPERFAMILY SSF49785 1397 1536 7.65E-40 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS35190 9c5f30336a826259fa66807c32f3dd49 1545 Pfam PF16353 Domain of unknown function(DUF4981) 882 968 2.5E-16 T 29-03-2018 IPR032312 Beta-galactosidase, domain 4 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 SMALA_RS35190 9c5f30336a826259fa66807c32f3dd49 1545 Gene3D G3DSA:2.70.98.10 978 1266 7.4E-78 T 29-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 SMALA_RS35190 9c5f30336a826259fa66807c32f3dd49 1545 PRINTS PR00132 Glycosyl hydrolase family 2 signature 504 519 1.7E-28 T 29-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 SMALA_RS35190 9c5f30336a826259fa66807c32f3dd49 1545 PRINTS PR00132 Glycosyl hydrolase family 2 signature 201 216 1.7E-28 T 29-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 SMALA_RS35190 9c5f30336a826259fa66807c32f3dd49 1545 PRINTS PR00132 Glycosyl hydrolase family 2 signature 577 592 1.7E-28 T 29-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 SMALA_RS35190 9c5f30336a826259fa66807c32f3dd49 1545 PRINTS PR00132 Glycosyl hydrolase family 2 signature 430 448 1.7E-28 T 29-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 SMALA_RS35190 9c5f30336a826259fa66807c32f3dd49 1545 PRINTS PR00132 Glycosyl hydrolase family 2 signature 399 413 1.7E-28 T 29-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 SMALA_RS35190 9c5f30336a826259fa66807c32f3dd49 1545 SUPERFAMILY SSF74650 983 1266 4.29E-64 T 29-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 SMALA_RS35190 9c5f30336a826259fa66807c32f3dd49 1545 Pfam PF10633 NPCBM-associated, NEW3 domain of alpha-galactosidase 1297 1371 2.9E-9 T 29-03-2018 IPR018905 Alpha-galactosidase, NEW3 domain SMALA_RS35190 9c5f30336a826259fa66807c32f3dd49 1545 Pfam PF00703 Glycosyl hydrolases family 2 275 388 1.7E-13 T 29-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 SMALA_RS35190 9c5f30336a826259fa66807c32f3dd49 1545 Gene3D G3DSA:2.60.40.10 868 974 9.6E-23 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS21195 f127db3385130323ac33e352a668ecf4 271 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 94 268 3.7E-46 T 29-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 SMALA_RS21195 f127db3385130323ac33e352a668ecf4 271 SUPERFAMILY SSF53335 39 268 3.41E-30 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS21195 f127db3385130323ac33e352a668ecf4 271 Pfam PF02390 Putative methyltransferase 96 263 1.8E-50 T 29-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 SMALA_RS21195 f127db3385130323ac33e352a668ecf4 271 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 48 269 28.274 T 29-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 SMALA_RS21195 f127db3385130323ac33e352a668ecf4 271 Gene3D G3DSA:3.40.50.150 54 271 4.8E-24 T 29-03-2018 SMALA_RS09180 e95c0a7ba64a26bfa29ffcceddd1753c 547 Gene3D G3DSA:3.40.50.880 301 524 5.2E-31 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS09180 e95c0a7ba64a26bfa29ffcceddd1753c 547 SUPERFAMILY SSF52317 234 279 3.01E-36 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS09180 e95c0a7ba64a26bfa29ffcceddd1753c 547 SUPERFAMILY SSF52317 314 466 3.01E-36 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS09180 e95c0a7ba64a26bfa29ffcceddd1753c 547 SUPERFAMILY SSF52540 20 112 4.91E-50 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS09180 e95c0a7ba64a26bfa29ffcceddd1753c 547 SUPERFAMILY SSF52540 153 281 4.91E-50 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS09180 e95c0a7ba64a26bfa29ffcceddd1753c 547 Hamap MF_00028 Cobyric acid synthase [cobQ]. 1 530 161.682 T 29-03-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 SMALA_RS09180 e95c0a7ba64a26bfa29ffcceddd1753c 547 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 20 272 3.4E-17 T 29-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain SMALA_RS09180 e95c0a7ba64a26bfa29ffcceddd1753c 547 Gene3D G3DSA:3.40.50.300 16 282 3.2E-51 T 29-03-2018 SMALA_RS09180 e95c0a7ba64a26bfa29ffcceddd1753c 547 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 302 473 4.8E-45 T 29-03-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 SMALA_RS37185 de95fd1d2ad96af92e8a7439bfc11fc1 286 SUPERFAMILY SSF47413 14 73 8.76E-8 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS37185 de95fd1d2ad96af92e8a7439bfc11fc1 286 SMART SM00530 18 73 6.2E-8 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS37185 de95fd1d2ad96af92e8a7439bfc11fc1 286 Gene3D G3DSA:1.10.3100.10 12 154 3.5E-14 T 29-03-2018 IPR027910 YdiL-like domain SMALA_RS37185 de95fd1d2ad96af92e8a7439bfc11fc1 286 Pfam PF13560 Helix-turn-helix domain 15 74 1.3E-11 T 29-03-2018 SMALA_RS03720 885b358406941b3af45e41d8ac84a60e 798 Gene3D G3DSA:1.10.10.10 438 519 1.9E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS03720 885b358406941b3af45e41d8ac84a60e 798 Gene3D G3DSA:1.10.10.10 520 605 2.1E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS03720 885b358406941b3af45e41d8ac84a60e 798 Gene3D G3DSA:1.10.10.10 378 435 9.1E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS03720 885b358406941b3af45e41d8ac84a60e 798 Gene3D G3DSA:1.10.10.10 606 656 3.7E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS03720 885b358406941b3af45e41d8ac84a60e 798 Gene3D G3DSA:1.10.10.10 657 742 9.1E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS03720 885b358406941b3af45e41d8ac84a60e 798 Gene3D G3DSA:1.10.510.10 99 281 1.6E-51 T 29-03-2018 SMALA_RS03720 885b358406941b3af45e41d8ac84a60e 798 Pfam PF13424 Tetratricopeptide repeat 429 497 2.4E-10 T 29-03-2018 SMALA_RS03720 885b358406941b3af45e41d8ac84a60e 798 SUPERFAMILY SSF56112 4 276 8.44E-77 T 29-03-2018 IPR011009 Protein kinase-like domain SMALA_RS03720 885b358406941b3af45e41d8ac84a60e 798 SUPERFAMILY SSF48452 587 727 6.44E-18 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS03720 885b358406941b3af45e41d8ac84a60e 798 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 17 40 - T 29-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 SMALA_RS03720 885b358406941b3af45e41d8ac84a60e 798 Pfam PF13374 Tetratricopeptide repeat 633 674 2.7E-10 T 29-03-2018 SMALA_RS03720 885b358406941b3af45e41d8ac84a60e 798 Pfam PF13374 Tetratricopeptide repeat 390 422 3.7E-4 T 29-03-2018 SMALA_RS03720 885b358406941b3af45e41d8ac84a60e 798 Pfam PF13374 Tetratricopeptide repeat 507 548 9.6E-7 T 29-03-2018 SMALA_RS03720 885b358406941b3af45e41d8ac84a60e 798 Pfam PF13374 Tetratricopeptide repeat 549 590 2.9E-6 T 29-03-2018 SMALA_RS03720 885b358406941b3af45e41d8ac84a60e 798 Pfam PF13374 Tetratricopeptide repeat 675 716 3.9E-6 T 29-03-2018 SMALA_RS03720 885b358406941b3af45e41d8ac84a60e 798 Gene3D G3DSA:3.30.200.20 2 98 2.0E-22 T 29-03-2018 SMALA_RS03720 885b358406941b3af45e41d8ac84a60e 798 Pfam PF00069 Protein kinase domain 11 268 1.5E-48 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMALA_RS03720 885b358406941b3af45e41d8ac84a60e 798 SMART SM00220 11 279 1.1E-64 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMALA_RS03720 885b358406941b3af45e41d8ac84a60e 798 SUPERFAMILY SSF48452 386 528 1.37E-16 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS07425 b4e24ec3e72082b07aa671f5b1f727f5 231 SUPERFAMILY SSF53254 1 208 5.78E-46 T 29-03-2018 IPR029033 Histidine phosphatase superfamily SMALA_RS07425 b4e24ec3e72082b07aa671f5b1f727f5 231 SMART SM00855 3 162 2.2E-22 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SMALA_RS07425 b4e24ec3e72082b07aa671f5b1f727f5 231 Gene3D G3DSA:3.40.50.1240 1 215 6.4E-43 T 29-03-2018 IPR029033 Histidine phosphatase superfamily SMALA_RS07425 b4e24ec3e72082b07aa671f5b1f727f5 231 TIGRFAM TIGR03848 MSMEG_4193: probable phosphomutase, MSMEG_4193 family 4 203 7.5E-94 T 29-03-2018 IPR022492 Phosphomutase MSMEG4193, putative SMALA_RS07425 b4e24ec3e72082b07aa671f5b1f727f5 231 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 202 4.0E-48 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SMALA_RS31365 b6928cfe43edaf86ddc96fa0c32a8156 335 SUPERFAMILY SSF51658 8 316 4.19E-55 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SMALA_RS31365 b6928cfe43edaf86ddc96fa0c32a8156 335 Pfam PF01261 Xylose isomerase-like TIM barrel 22 272 2.3E-36 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SMALA_RS31365 b6928cfe43edaf86ddc96fa0c32a8156 335 Pfam PF07582 AP endonuclease family 2 C terminus 275 329 1.3E-23 T 29-03-2018 IPR011418 AP endonuclease, family 2, C-terminal SMALA_RS31365 b6928cfe43edaf86ddc96fa0c32a8156 335 Gene3D G3DSA:3.20.20.150 1 317 1.2E-57 T 29-03-2018 SMALA_RS33940 441fc12a28e89c7bc465131c20752299 461 ProSitePatterns PS00591 Glycosyl hydrolases family 10 (GH10) active site. 272 282 - T 29-03-2018 IPR031158 Glycosyl hydrolases family 10, active site MetaCyc: PWY-6784 SMALA_RS33940 441fc12a28e89c7bc465131c20752299 461 Gene3D G3DSA:2.60.40.290 360 461 4.7E-22 T 29-03-2018 SMALA_RS33940 441fc12a28e89c7bc465131c20752299 461 SMART SM00637 363 458 6.7E-21 T 29-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 SMALA_RS33940 441fc12a28e89c7bc465131c20752299 461 SMART SM00633 90 346 8.6E-138 T 29-03-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 SMALA_RS33940 441fc12a28e89c7bc465131c20752299 461 PRINTS PR00134 Glycosyl hydrolase family 10 signature 121 133 4.7E-18 T 29-03-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 SMALA_RS33940 441fc12a28e89c7bc465131c20752299 461 PRINTS PR00134 Glycosyl hydrolase family 10 signature 163 174 4.7E-18 T 29-03-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 SMALA_RS33940 441fc12a28e89c7bc465131c20752299 461 PRINTS PR00134 Glycosyl hydrolase family 10 signature 209 220 4.7E-18 T 29-03-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 SMALA_RS33940 441fc12a28e89c7bc465131c20752299 461 PRINTS PR00134 Glycosyl hydrolase family 10 signature 238 250 4.7E-18 T 29-03-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 SMALA_RS33940 441fc12a28e89c7bc465131c20752299 461 Pfam PF00331 Glycosyl hydrolase family 10 51 344 1.5E-118 T 29-03-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 SMALA_RS33940 441fc12a28e89c7bc465131c20752299 461 Gene3D G3DSA:3.20.20.80 40 353 4.7E-75 T 29-03-2018 SMALA_RS33940 441fc12a28e89c7bc465131c20752299 461 SUPERFAMILY SSF51445 52 348 1.46E-115 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS33940 441fc12a28e89c7bc465131c20752299 461 Pfam PF00553 Cellulose binding domain 363 455 1.6E-11 T 29-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 SMALA_RS33940 441fc12a28e89c7bc465131c20752299 461 SUPERFAMILY SSF49384 359 455 2.65E-19 T 29-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 SMALA_RS25165 71a8ae37ef4c07902d8bf35695266007 630 Gene3D G3DSA:2.140.10.30 5 119 9.9E-12 T 29-03-2018 SMALA_RS25165 71a8ae37ef4c07902d8bf35695266007 630 Gene3D G3DSA:2.140.10.30 120 358 1.4E-15 T 29-03-2018 SMALA_RS25165 71a8ae37ef4c07902d8bf35695266007 630 Gene3D G3DSA:3.40.50.1820 359 630 3.2E-49 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS25165 71a8ae37ef4c07902d8bf35695266007 630 Pfam PF00326 Prolyl oligopeptidase family 410 625 1.4E-46 T 29-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 SMALA_RS25165 71a8ae37ef4c07902d8bf35695266007 630 SUPERFAMILY SSF53474 365 624 8.04E-69 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS25165 71a8ae37ef4c07902d8bf35695266007 630 SUPERFAMILY SSF82171 21 250 7.65E-18 T 29-03-2018 SMALA_RS25165 71a8ae37ef4c07902d8bf35695266007 630 SUPERFAMILY SSF82171 305 356 7.65E-18 T 29-03-2018 SMALA_RS19110 8df0c4af93eb73bb145f6df6fa3ffc11 602 SMART SM00388 256 323 2.4E-21 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS19110 8df0c4af93eb73bb145f6df6fa3ffc11 602 SMART SM00304 186 248 2.6E-6 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMALA_RS19110 8df0c4af93eb73bb145f6df6fa3ffc11 602 Pfam PF00512 His Kinase A (phospho-acceptor) domain 258 323 5.5E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS19110 8df0c4af93eb73bb145f6df6fa3ffc11 602 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 366 573 4.1E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS19110 8df0c4af93eb73bb145f6df6fa3ffc11 602 Pfam PF00672 HAMP domain 189 243 3.9E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMALA_RS19110 8df0c4af93eb73bb145f6df6fa3ffc11 602 SUPERFAMILY SSF47384 243 324 1.28E-18 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS19110 8df0c4af93eb73bb145f6df6fa3ffc11 602 Gene3D G3DSA:1.10.287.130 242 319 2.8E-16 T 29-03-2018 SMALA_RS19110 8df0c4af93eb73bb145f6df6fa3ffc11 602 PRINTS PR00344 Bacterial sensor protein C-terminal signature 559 572 1.7E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS19110 8df0c4af93eb73bb145f6df6fa3ffc11 602 PRINTS PR00344 Bacterial sensor protein C-terminal signature 536 554 1.7E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS19110 8df0c4af93eb73bb145f6df6fa3ffc11 602 PRINTS PR00344 Bacterial sensor protein C-terminal signature 501 515 1.7E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS19110 8df0c4af93eb73bb145f6df6fa3ffc11 602 PRINTS PR00344 Bacterial sensor protein C-terminal signature 519 529 1.7E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS19110 8df0c4af93eb73bb145f6df6fa3ffc11 602 SUPERFAMILY SSF55874 499 575 8.91E-23 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS19110 8df0c4af93eb73bb145f6df6fa3ffc11 602 Gene3D G3DSA:3.30.565.10 326 580 8.0E-37 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS19110 8df0c4af93eb73bb145f6df6fa3ffc11 602 SMART SM00387 366 575 1.7E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS19110 8df0c4af93eb73bb145f6df6fa3ffc11 602 SUPERFAMILY SSF55874 312 400 1.34E-11 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS05280 34e001a5c067471237ef1430c6410620 542 Gene3D G3DSA:3.40.190.10 213 541 1.7E-27 T 29-03-2018 SMALA_RS05280 34e001a5c067471237ef1430c6410620 542 SUPERFAMILY SSF53850 91 539 1.56E-50 T 29-03-2018 SMALA_RS05280 34e001a5c067471237ef1430c6410620 542 Pfam PF13416 Bacterial extracellular solute-binding protein 117 407 1.7E-11 T 29-03-2018 SMALA_RS00550 55ed52535797b99f79fdd014f3760c65 211 Gene3D G3DSA:1.10.357.10 70 199 1.2E-7 T 29-03-2018 SMALA_RS00550 55ed52535797b99f79fdd014f3760c65 211 SUPERFAMILY SSF46689 8 88 3.29E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS00550 55ed52535797b99f79fdd014f3760c65 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 2.4E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS00550 55ed52535797b99f79fdd014f3760c65 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 2.4E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS00550 55ed52535797b99f79fdd014f3760c65 211 SUPERFAMILY SSF48498 84 190 2.82E-13 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS00550 55ed52535797b99f79fdd014f3760c65 211 Gene3D G3DSA:1.10.260.40 42 69 1.9E-10 T 29-03-2018 SMALA_RS00550 55ed52535797b99f79fdd014f3760c65 211 Gene3D G3DSA:1.10.10.60 2 41 7.0E-15 T 29-03-2018 SMALA_RS00550 55ed52535797b99f79fdd014f3760c65 211 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 64 2.2E-14 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS22570 61583388d964e7d7ca5a754e90a51804 139 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 29-03-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS22570 61583388d964e7d7ca5a754e90a51804 139 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 37.748 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS22570 61583388d964e7d7ca5a754e90a51804 139 Gene3D G3DSA:3.90.1170.10 3 139 2.3E-49 T 29-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 SMALA_RS22570 61583388d964e7d7ca5a754e90a51804 139 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 3.8E-47 T 29-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 SMALA_RS22570 61583388d964e7d7ca5a754e90a51804 139 PRINTS PR00060 Ribosomal protein L16 signature 58 87 3.3E-38 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS22570 61583388d964e7d7ca5a754e90a51804 139 PRINTS PR00060 Ribosomal protein L16 signature 24 36 3.3E-38 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS22570 61583388d964e7d7ca5a754e90a51804 139 PRINTS PR00060 Ribosomal protein L16 signature 42 53 3.3E-38 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS22570 61583388d964e7d7ca5a754e90a51804 139 PRINTS PR00060 Ribosomal protein L16 signature 88 117 3.3E-38 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS22570 61583388d964e7d7ca5a754e90a51804 139 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 127 4.9E-54 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS22570 61583388d964e7d7ca5a754e90a51804 139 SUPERFAMILY SSF54686 1 135 1.2E-54 T 29-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 SMALA_RS22570 61583388d964e7d7ca5a754e90a51804 139 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 29-03-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS09855 c8f55ebdf0e5756471f47b0e6b7f5b71 151 Pfam PF00293 NUDIX domain 3 122 4.0E-19 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SMALA_RS09855 c8f55ebdf0e5756471f47b0e6b7f5b71 151 ProSitePatterns PS00893 Nudix box signature. 38 59 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 SMALA_RS09855 c8f55ebdf0e5756471f47b0e6b7f5b71 151 PRINTS PR00502 NUDIX hydrolase family signature 47 62 2.3E-6 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMALA_RS09855 c8f55ebdf0e5756471f47b0e6b7f5b71 151 PRINTS PR00502 NUDIX hydrolase family signature 33 47 2.3E-6 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMALA_RS09855 c8f55ebdf0e5756471f47b0e6b7f5b71 151 Gene3D G3DSA:3.90.79.10 1 141 2.6E-26 T 29-03-2018 SMALA_RS09855 c8f55ebdf0e5756471f47b0e6b7f5b71 151 SUPERFAMILY SSF55811 4 135 2.71E-28 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMALA_RS00245 2474d8ba55f1142a789b16f43bc8a5b5 192 Pfam PF04978 Protein of unknown function (DUF664) 18 188 1.8E-42 T 29-03-2018 IPR007061 Protein of unknown function DUF664 SMALA_RS00245 2474d8ba55f1142a789b16f43bc8a5b5 192 Gene3D G3DSA:1.20.120.450 1 192 4.1E-35 T 29-03-2018 SMALA_RS00245 2474d8ba55f1142a789b16f43bc8a5b5 192 SUPERFAMILY SSF109854 5 187 4.12E-35 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes SMALA_RS22285 674440e5b32962c923a04ac1257c2192 234 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 100 111 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site SMALA_RS22285 674440e5b32962c923a04ac1257c2192 234 Gene3D G3DSA:3.30.70.20 19 62 2.8E-5 T 29-03-2018 SMALA_RS22285 674440e5b32962c923a04ac1257c2192 234 Hamap MF_01351 NAD(P)H-quinone oxidoreductase subunit I, chloroplastic [ndhI]. 3 170 24.193 T 29-03-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS22285 674440e5b32962c923a04ac1257c2192 234 Gene3D G3DSA:3.30.70.20 63 102 2.0E-10 T 29-03-2018 SMALA_RS22285 674440e5b32962c923a04ac1257c2192 234 SUPERFAMILY SSF54862 34 143 1.26E-18 T 29-03-2018 SMALA_RS22285 674440e5b32962c923a04ac1257c2192 234 Gene3D G3DSA:3.30.70.20 103 190 7.7E-6 T 29-03-2018 SMALA_RS22285 674440e5b32962c923a04ac1257c2192 234 Pfam PF00037 4Fe-4S binding domain 95 115 5.4E-8 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain SMALA_RS02065 c8955aab2b94e22d3b7600a11df96028 208 Pfam PF13532 2OG-Fe(II) oxygenase superfamily 110 203 5.5E-13 T 29-03-2018 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like SMALA_RS02065 c8955aab2b94e22d3b7600a11df96028 208 Gene3D G3DSA:2.60.120.590 35 205 5.3E-31 T 29-03-2018 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like SMALA_RS02065 c8955aab2b94e22d3b7600a11df96028 208 SUPERFAMILY SSF51197 33 203 6.87E-40 T 29-03-2018 SMALA_RS02045 873bb92d6e9bc6de953a60fb25125785 646 ProSitePatterns PS00109 Tyrosine protein kinases specific active-site signature. 128 140 - T 29-03-2018 IPR008266 Tyrosine-protein kinase, active site GO:0004672|GO:0006468 SMALA_RS02045 873bb92d6e9bc6de953a60fb25125785 646 SUPERFAMILY SSF56112 7 278 4.53E-69 T 29-03-2018 IPR011009 Protein kinase-like domain SMALA_RS02045 873bb92d6e9bc6de953a60fb25125785 646 Gene3D G3DSA:3.30.200.20 1 91 2.8E-25 T 29-03-2018 SMALA_RS02045 873bb92d6e9bc6de953a60fb25125785 646 Pfam PF00069 Protein kinase domain 14 258 9.5E-47 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMALA_RS02045 873bb92d6e9bc6de953a60fb25125785 646 Gene3D G3DSA:1.10.510.10 92 310 4.7E-47 T 29-03-2018 SMALA_RS02045 873bb92d6e9bc6de953a60fb25125785 646 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 18 41 - T 29-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 SMALA_RS08595 9fd6b42b8d76ffc14e670a4207909ab5 239 Pfam PF06386 Gas vesicle synthesis protein GvpL/GvpF 3 237 2.3E-61 T 29-03-2018 IPR009430 Gas vesicle protein GvpL/GvpF GO:0031411|GO:0031412 SMALA_RS07185 3c1350eb3257dbdf2399e1c192dee422 940 SMART SM00490 354 446 5.0E-12 T 29-03-2018 IPR001650 Helicase, C-terminal SMALA_RS07185 3c1350eb3257dbdf2399e1c192dee422 940 Gene3D G3DSA:3.40.50.300 8 208 1.8E-36 T 29-03-2018 SMALA_RS07185 3c1350eb3257dbdf2399e1c192dee422 940 Gene3D G3DSA:3.40.50.300 288 581 5.5E-16 T 29-03-2018 SMALA_RS07185 3c1350eb3257dbdf2399e1c192dee422 940 SMART SM01142 763 939 1.0E-61 T 29-03-2018 IPR012961 ATP-dependent RNA helicase Ski2, C-terminal SMALA_RS07185 3c1350eb3257dbdf2399e1c192dee422 940 Pfam PF00270 DEAD/DEAH box helicase 38 185 1.2E-19 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 SMALA_RS07185 3c1350eb3257dbdf2399e1c192dee422 940 SUPERFAMILY SSF52540 366 459 3.58E-43 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS07185 3c1350eb3257dbdf2399e1c192dee422 940 SUPERFAMILY SSF52540 47 187 3.58E-43 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS07185 3c1350eb3257dbdf2399e1c192dee422 940 SUPERFAMILY SSF52540 272 324 3.58E-43 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS07185 3c1350eb3257dbdf2399e1c192dee422 940 Pfam PF00271 Helicase conserved C-terminal domain 367 446 1.5E-4 T 29-03-2018 IPR001650 Helicase, C-terminal SMALA_RS07185 3c1350eb3257dbdf2399e1c192dee422 940 Pfam PF13234 rRNA-processing arch domain 502 602 3.0E-4 T 29-03-2018 IPR025696 rRNA-processing arch domain SMALA_RS07185 3c1350eb3257dbdf2399e1c192dee422 940 Pfam PF08148 DSHCT (NUC185) domain 766 934 4.5E-36 T 29-03-2018 IPR012961 ATP-dependent RNA helicase Ski2, C-terminal SMALA_RS07185 3c1350eb3257dbdf2399e1c192dee422 940 SMART SM00487 32 214 3.9E-30 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain SMALA_RS01890 75c4eb6ef49386dbe45a6e8efd6bacb7 852 Pfam PF08124 Polysaccharide lyase family 8, N terminal alpha-helical domain 62 379 1.3E-54 T 29-03-2018 IPR012970 Polysaccharide lyase 8, N-terminal alpha-helical SMALA_RS01890 75c4eb6ef49386dbe45a6e8efd6bacb7 852 Gene3D G3DSA:1.50.10.100 40 420 5.1E-84 T 29-03-2018 SMALA_RS01890 75c4eb6ef49386dbe45a6e8efd6bacb7 852 Pfam PF02884 Polysaccharide lyase family 8, C-terminal beta-sandwich domain 740 806 3.0E-16 T 29-03-2018 IPR004103 Polysaccharide lyase family 8, C-terminal GO:0005576|GO:0016829 SMALA_RS01890 75c4eb6ef49386dbe45a6e8efd6bacb7 852 SUPERFAMILY SSF48230 61 386 1.21E-55 T 29-03-2018 IPR008929 Chondroitin AC/alginate lyase Reactome: R-HSA-2022923 SMALA_RS01890 75c4eb6ef49386dbe45a6e8efd6bacb7 852 SUPERFAMILY SSF48230 424 445 1.21E-55 T 29-03-2018 IPR008929 Chondroitin AC/alginate lyase Reactome: R-HSA-2022923 SMALA_RS01890 75c4eb6ef49386dbe45a6e8efd6bacb7 852 Gene3D G3DSA:2.60.220.10 740 852 7.7E-25 T 29-03-2018 SMALA_RS01890 75c4eb6ef49386dbe45a6e8efd6bacb7 852 SUPERFAMILY SSF49863 738 851 4.71E-21 T 29-03-2018 IPR011071 Polysaccharide lyase family 8-like, C-terminal GO:0005975 SMALA_RS01890 75c4eb6ef49386dbe45a6e8efd6bacb7 852 SUPERFAMILY SSF74650 424 738 6.8E-41 T 29-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 SMALA_RS01890 75c4eb6ef49386dbe45a6e8efd6bacb7 852 Pfam PF02278 Polysaccharide lyase family 8, super-sandwich domain 425 726 8.0E-64 T 29-03-2018 IPR003159 Polysaccharide lyase family 8, central domain GO:0005576|GO:0016829 SMALA_RS01890 75c4eb6ef49386dbe45a6e8efd6bacb7 852 Gene3D G3DSA:2.70.98.10 422 739 2.8E-68 T 29-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 SMALA_RS06920 f4adb68b265e4729acb29fae2f06b207 149 Gene3D G3DSA:1.10.20.10 2 149 2.7E-22 T 29-03-2018 SMALA_RS06920 f4adb68b265e4729acb29fae2f06b207 149 SUPERFAMILY SSF47113 2 149 1.81E-57 T 29-03-2018 IPR009072 Histone-fold GO:0046982 SMALA_RS06920 f4adb68b265e4729acb29fae2f06b207 149 Pfam PF09123 Domain of unknown function (DUF1931) 9 145 7.3E-59 T 29-03-2018 IPR015207 Protein of unknown function DUF1931 SMALA_RS41240 43fec38a95ea86c2afd7f7297c0dcf29 267 Gene3D G3DSA:3.40.50.620 1 124 1.2E-20 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS41240 43fec38a95ea86c2afd7f7297c0dcf29 267 SUPERFAMILY SSF52402 1 123 1.42E-21 T 29-03-2018 SMALA_RS41240 43fec38a95ea86c2afd7f7297c0dcf29 267 Gene3D G3DSA:3.40.50.620 125 267 1.7E-17 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS41240 43fec38a95ea86c2afd7f7297c0dcf29 267 PRINTS PR01438 Universal stress protein signature 96 118 1.4E-6 T 29-03-2018 IPR006015 Universal stress protein A SMALA_RS41240 43fec38a95ea86c2afd7f7297c0dcf29 267 PRINTS PR01438 Universal stress protein signature 78 90 1.4E-6 T 29-03-2018 IPR006015 Universal stress protein A SMALA_RS41240 43fec38a95ea86c2afd7f7297c0dcf29 267 SUPERFAMILY SSF52402 134 265 3.93E-15 T 29-03-2018 SMALA_RS41240 43fec38a95ea86c2afd7f7297c0dcf29 267 Pfam PF00582 Universal stress protein family 129 265 6.1E-15 T 29-03-2018 IPR006016 UspA GO:0006950 SMALA_RS41240 43fec38a95ea86c2afd7f7297c0dcf29 267 Pfam PF00582 Universal stress protein family 2 118 1.3E-11 T 29-03-2018 IPR006016 UspA GO:0006950 SMALA_RS22710 80db07bd2297937119f5f931615a15f2 339 Gene3D G3DSA:3.60.40.10 145 334 9.9E-17 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS22710 80db07bd2297937119f5f931615a15f2 339 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 176 333 4.1E-10 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS22710 80db07bd2297937119f5f931615a15f2 339 Gene3D G3DSA:3.30.565.10 6 144 3.3E-10 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS22710 80db07bd2297937119f5f931615a15f2 339 SUPERFAMILY SSF55874 30 125 4.16E-9 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS22710 80db07bd2297937119f5f931615a15f2 339 SMART SM00331 146 334 4.4E-9 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS22710 80db07bd2297937119f5f931615a15f2 339 SUPERFAMILY SSF81606 148 333 1.96E-11 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS02805 bf25bea0394963a4d9a45596992dbe6e 202 Pfam PF00929 Exonuclease 5 185 1.2E-10 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III SMALA_RS02805 bf25bea0394963a4d9a45596992dbe6e 202 SMART SM00479 3 196 5.9E-6 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III SMALA_RS02805 bf25bea0394963a4d9a45596992dbe6e 202 Gene3D G3DSA:3.30.420.10 1 198 1.7E-17 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SMALA_RS02805 bf25bea0394963a4d9a45596992dbe6e 202 SUPERFAMILY SSF53098 3 190 4.55E-16 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SMALA_RS41350 ba375c6dc42c92b694823ed3bd2a1983 220 Pfam PF07969 Amidohydrolase family 107 201 2.7E-11 T 29-03-2018 IPR013108 Amidohydrolase 3 SMALA_RS41350 ba375c6dc42c92b694823ed3bd2a1983 220 Gene3D G3DSA:3.20.20.140 21 176 2.0E-16 T 29-03-2018 SMALA_RS41350 ba375c6dc42c92b694823ed3bd2a1983 220 SUPERFAMILY SSF51338 157 217 1.11E-11 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS41350 ba375c6dc42c92b694823ed3bd2a1983 220 SUPERFAMILY SSF51556 61 145 6.8E-8 T 29-03-2018 IPR032466 Metal-dependent hydrolase SMALA_RS02975 7811959cd51973d4ad60ddf2d149fb91 732 Gene3D G3DSA:2.70.150.10 18 239 1.7E-27 T 29-03-2018 SMALA_RS02975 7811959cd51973d4ad60ddf2d149fb91 732 Pfam PF00122 E1-E2 ATPase 138 315 1.8E-41 T 29-03-2018 SMALA_RS02975 7811959cd51973d4ad60ddf2d149fb91 732 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 600 619 5.9E-17 T 29-03-2018 SMALA_RS02975 7811959cd51973d4ad60ddf2d149fb91 732 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 624 636 5.9E-17 T 29-03-2018 SMALA_RS02975 7811959cd51973d4ad60ddf2d149fb91 732 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 338 352 5.9E-17 T 29-03-2018 SMALA_RS02975 7811959cd51973d4ad60ddf2d149fb91 732 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 188 202 5.9E-17 T 29-03-2018 SMALA_RS02975 7811959cd51973d4ad60ddf2d149fb91 732 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 547 557 5.9E-17 T 29-03-2018 SMALA_RS02975 7811959cd51973d4ad60ddf2d149fb91 732 Gene3D G3DSA:3.40.50.1000 527 667 7.0E-32 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS02975 7811959cd51973d4ad60ddf2d149fb91 732 SUPERFAMILY SSF56784 515 700 6.25E-45 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS02975 7811959cd51973d4ad60ddf2d149fb91 732 SUPERFAMILY SSF56784 337 356 6.25E-45 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS02975 7811959cd51973d4ad60ddf2d149fb91 732 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 111 376 6.1E-33 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMALA_RS02975 7811959cd51973d4ad60ddf2d149fb91 732 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 498 667 3.5E-29 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMALA_RS02975 7811959cd51973d4ad60ddf2d149fb91 732 Pfam PF00702 haloacid dehalogenase-like hydrolase 337 613 3.6E-34 T 29-03-2018 SMALA_RS02975 7811959cd51973d4ad60ddf2d149fb91 732 SUPERFAMILY SSF81653 143 238 1.7E-22 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 SMALA_RS02975 7811959cd51973d4ad60ddf2d149fb91 732 Gene3D G3DSA:3.40.1110.10 349 526 6.7E-27 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 SMALA_RS02975 7811959cd51973d4ad60ddf2d149fb91 732 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 340 346 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 SMALA_RS02975 7811959cd51973d4ad60ddf2d149fb91 732 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 87 427 5.9E-105 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 SMALA_RS02975 7811959cd51973d4ad60ddf2d149fb91 732 SUPERFAMILY SSF81660 356 431 1.14E-17 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 SMALA_RS02975 7811959cd51973d4ad60ddf2d149fb91 732 ProSitePatterns PS01229 Hypothetical cof family signature 2. 600 622 - T 29-03-2018 SMALA_RS02975 7811959cd51973d4ad60ddf2d149fb91 732 PRINTS PR00941 Cadmium-transporting ATPase signature 122 142 1.2E-6 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 SMALA_RS02975 7811959cd51973d4ad60ddf2d149fb91 732 PRINTS PR00941 Cadmium-transporting ATPase signature 223 237 1.2E-6 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 SMALA_RS02975 7811959cd51973d4ad60ddf2d149fb91 732 PRINTS PR00941 Cadmium-transporting ATPase signature 204 220 1.2E-6 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 SMALA_RS02975 7811959cd51973d4ad60ddf2d149fb91 732 SUPERFAMILY SSF81665 89 141 9.29E-12 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SMALA_RS02975 7811959cd51973d4ad60ddf2d149fb91 732 SUPERFAMILY SSF81665 239 332 9.29E-12 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SMALA_RS33310 1c300761d82047611fa3cdea4e94a8eb 90 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 7 90 2.2E-24 T 29-03-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 SMALA_RS33310 1c300761d82047611fa3cdea4e94a8eb 90 Gene3D G3DSA:1.10.287.1080 1 90 1.6E-16 T 29-03-2018 SMALA_RS33310 1c300761d82047611fa3cdea4e94a8eb 90 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 10 89 2.6E-10 T 29-03-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 SMALA_RS33310 1c300761d82047611fa3cdea4e94a8eb 90 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 3 90 19.119 T 29-03-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 SMALA_RS33310 1c300761d82047611fa3cdea4e94a8eb 90 SUPERFAMILY SSF101386 5 90 3.05E-20 T 29-03-2018 SMALA_RS10960 2e2c165d0d13434d402234b1d32747be 404 Gene3D G3DSA:1.20.1250.20 193 381 4.0E-22 T 29-03-2018 SMALA_RS10960 2e2c165d0d13434d402234b1d32747be 404 SUPERFAMILY SSF103473 3 375 8.63E-62 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS10960 2e2c165d0d13434d402234b1d32747be 404 Gene3D G3DSA:1.20.1250.20 2 187 1.1E-32 T 29-03-2018 SMALA_RS10960 2e2c165d0d13434d402234b1d32747be 404 Pfam PF07690 Major Facilitator Superfamily 9 339 6.4E-46 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS06110 fb13f5518ba9a9334851be1b5d19b43e 271 Pfam PF00561 alpha/beta hydrolase fold 23 249 9.9E-20 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS06110 fb13f5518ba9a9334851be1b5d19b43e 271 PRINTS PR00111 Alpha/beta hydrolase fold signature 207 221 1.8E-22 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS06110 fb13f5518ba9a9334851be1b5d19b43e 271 PRINTS PR00111 Alpha/beta hydrolase fold signature 48 63 1.8E-22 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS06110 fb13f5518ba9a9334851be1b5d19b43e 271 PRINTS PR00111 Alpha/beta hydrolase fold signature 93 106 1.8E-22 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS06110 fb13f5518ba9a9334851be1b5d19b43e 271 PRINTS PR00111 Alpha/beta hydrolase fold signature 107 120 1.8E-22 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS06110 fb13f5518ba9a9334851be1b5d19b43e 271 Gene3D G3DSA:3.40.50.1820 2 263 2.7E-48 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS06110 fb13f5518ba9a9334851be1b5d19b43e 271 SUPERFAMILY SSF53474 3 262 5.49E-63 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS15645 51a46a18cc0bcbc114099a911b8913cd 950 SUPERFAMILY SSF81886 627 850 4.58E-74 T 29-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 SMALA_RS15645 51a46a18cc0bcbc114099a911b8913cd 950 Hamap MF_01382 Protein translocase subunit SecA [secA]. 3 841 20.04 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 SMALA_RS15645 51a46a18cc0bcbc114099a911b8913cd 950 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 26 827 0.0 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 SMALA_RS15645 51a46a18cc0bcbc114099a911b8913cd 950 SMART SM00957 4 394 1.7E-284 T 29-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 SMALA_RS15645 51a46a18cc0bcbc114099a911b8913cd 950 Gene3D G3DSA:3.40.50.300 409 640 4.0E-55 T 29-03-2018 SMALA_RS15645 51a46a18cc0bcbc114099a911b8913cd 950 Gene3D G3DSA:1.10.3060.10 641 730 1.6E-27 T 29-03-2018 SMALA_RS15645 51a46a18cc0bcbc114099a911b8913cd 950 Pfam PF07517 SecA DEAD-like domain 6 393 7.8E-130 T 29-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 SMALA_RS15645 51a46a18cc0bcbc114099a911b8913cd 950 Gene3D G3DSA:3.10.450.50 731 949 3.2E-39 T 29-03-2018 SMALA_RS15645 51a46a18cc0bcbc114099a911b8913cd 950 SUPERFAMILY SSF52540 408 625 2.78E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS15645 51a46a18cc0bcbc114099a911b8913cd 950 Pfam PF01043 SecA preprotein cross-linking domain 231 350 1.9E-34 T 29-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 SMALA_RS15645 51a46a18cc0bcbc114099a911b8913cd 950 Pfam PF07516 SecA Wing and Scaffold domain 624 838 6.7E-66 T 29-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 SMALA_RS15645 51a46a18cc0bcbc114099a911b8913cd 950 ProSitePatterns PS01312 SecA family signature. 492 507 - T 29-03-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 SMALA_RS15645 51a46a18cc0bcbc114099a911b8913cd 950 Gene3D G3DSA:3.40.50.300 298 408 4.4E-9 T 29-03-2018 SMALA_RS15645 51a46a18cc0bcbc114099a911b8913cd 950 Gene3D G3DSA:3.40.50.300 7 271 6.5E-52 T 29-03-2018 SMALA_RS15645 51a46a18cc0bcbc114099a911b8913cd 950 SUPERFAMILY SSF52540 360 407 2.45E-80 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS15645 51a46a18cc0bcbc114099a911b8913cd 950 SUPERFAMILY SSF52540 4 226 2.45E-80 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS15645 51a46a18cc0bcbc114099a911b8913cd 950 PRINTS PR00906 SecA protein signature 168 188 5.1E-70 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 SMALA_RS15645 51a46a18cc0bcbc114099a911b8913cd 950 PRINTS PR00906 SecA protein signature 405 418 5.1E-70 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 SMALA_RS15645 51a46a18cc0bcbc114099a911b8913cd 950 PRINTS PR00906 SecA protein signature 115 125 5.1E-70 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 SMALA_RS15645 51a46a18cc0bcbc114099a911b8913cd 950 PRINTS PR00906 SecA protein signature 331 353 5.1E-70 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 SMALA_RS15645 51a46a18cc0bcbc114099a911b8913cd 950 PRINTS PR00906 SecA protein signature 61 85 5.1E-70 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 SMALA_RS15645 51a46a18cc0bcbc114099a911b8913cd 950 PRINTS PR00906 SecA protein signature 99 113 5.1E-70 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 SMALA_RS15645 51a46a18cc0bcbc114099a911b8913cd 950 PRINTS PR00906 SecA protein signature 368 385 5.1E-70 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 SMALA_RS15645 51a46a18cc0bcbc114099a911b8913cd 950 SMART SM00958 226 350 2.7E-65 T 29-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 SMALA_RS15645 51a46a18cc0bcbc114099a911b8913cd 950 SUPERFAMILY SSF81767 225 360 1.96E-40 T 29-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 SMALA_RS35540 b4ec25ffe5ef4202a061af2e046c4f1d 1453 SUPERFAMILY SSF48452 1136 1273 2.95E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS35540 b4ec25ffe5ef4202a061af2e046c4f1d 1453 Gene3D G3DSA:3.40.50.300 624 783 5.1E-12 T 29-03-2018 SMALA_RS35540 b4ec25ffe5ef4202a061af2e046c4f1d 1453 SUPERFAMILY SSF52540 624 879 3.04E-32 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS35540 b4ec25ffe5ef4202a061af2e046c4f1d 1453 Gene3D G3DSA:1.10.10.10 1366 1449 5.1E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS35540 b4ec25ffe5ef4202a061af2e046c4f1d 1453 Gene3D G3DSA:1.10.10.10 1028 1119 1.1E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS35540 b4ec25ffe5ef4202a061af2e046c4f1d 1453 Gene3D G3DSA:1.10.10.10 1282 1365 5.1E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS35540 b4ec25ffe5ef4202a061af2e046c4f1d 1453 Gene3D G3DSA:1.10.10.10 1120 1193 0.01 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS35540 b4ec25ffe5ef4202a061af2e046c4f1d 1453 Gene3D G3DSA:1.10.10.10 1196 1281 1.5E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS35540 b4ec25ffe5ef4202a061af2e046c4f1d 1453 SUPERFAMILY SSF48452 1012 1092 1.4E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS35540 b4ec25ffe5ef4202a061af2e046c4f1d 1453 SUPERFAMILY SSF48452 1227 1337 4.43E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS35540 b4ec25ffe5ef4202a061af2e046c4f1d 1453 Pfam PF13424 Tetratricopeptide repeat 1267 1339 1.0E-8 T 29-03-2018 SMALA_RS35540 b4ec25ffe5ef4202a061af2e046c4f1d 1453 Pfam PF13424 Tetratricopeptide repeat 1352 1425 1.3E-9 T 29-03-2018 SMALA_RS35540 b4ec25ffe5ef4202a061af2e046c4f1d 1453 Pfam PF00931 NB-ARC domain 661 830 2.1E-10 T 29-03-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207 SMALA_RS35540 b4ec25ffe5ef4202a061af2e046c4f1d 1453 SUPERFAMILY SSF48452 1304 1425 3.79E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS42160 7f4d6f3685f91029f610c5631a06a027 233 Gene3D G3DSA:2.60.120.10 41 203 6.5E-22 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SMALA_RS42160 7f4d6f3685f91029f610c5631a06a027 233 Hamap MF_01682 Acireductone dioxygenase [mtnD]. 40 218 26.217 T 29-03-2018 IPR023956 Acireductone dioxygenase ARD, bacteria GO:0005506|GO:0010308|GO:0010309|GO:0016151|GO:0019284|GO:0055114 KEGG: 00270+1.13.11.53+1.13.11.54|MetaCyc: PWY-4361|MetaCyc: PWY-5389 SMALA_RS42160 7f4d6f3685f91029f610c5631a06a027 233 SUPERFAMILY SSF51182 52 227 8.6E-27 T 29-03-2018 IPR011051 RmlC-like cupin domain SMALA_RS42160 7f4d6f3685f91029f610c5631a06a027 233 Pfam PF03079 ARD/ARD' family 133 210 1.7E-17 T 29-03-2018 IPR004313 Acireductone dioxygenase ARD family GO:0010309|GO:0055114 KEGG: 00270+1.13.11.54|MetaCyc: PWY-4361|Reactome: R-HSA-1237112 SMALA_RS22860 bfec9566d50e81921db09f6703c6a2ce 293 Pfam PF00561 alpha/beta hydrolase fold 31 138 2.2E-19 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS22860 bfec9566d50e81921db09f6703c6a2ce 293 Gene3D G3DSA:3.40.50.1820 2 293 3.1E-44 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS22860 bfec9566d50e81921db09f6703c6a2ce 293 PRINTS PR00412 Epoxide hydrolase signature 36 54 7.7E-7 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS22860 bfec9566d50e81921db09f6703c6a2ce 293 PRINTS PR00412 Epoxide hydrolase signature 268 290 7.7E-7 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS22860 bfec9566d50e81921db09f6703c6a2ce 293 PRINTS PR00412 Epoxide hydrolase signature 104 117 7.7E-7 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS22860 bfec9566d50e81921db09f6703c6a2ce 293 SUPERFAMILY SSF53474 4 293 6.77E-61 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS24500 ddd643ee952c6500db1d3ddc4e517834 411 SUPERFAMILY SSF53613 27 119 3.73E-51 T 29-03-2018 IPR029056 Ribokinase-like SMALA_RS24500 ddd643ee952c6500db1d3ddc4e517834 411 SUPERFAMILY SSF53613 148 366 3.73E-51 T 29-03-2018 IPR029056 Ribokinase-like SMALA_RS24500 ddd643ee952c6500db1d3ddc4e517834 411 Pfam PF00294 pfkB family carbohydrate kinase 160 360 2.0E-22 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB SMALA_RS24500 ddd643ee952c6500db1d3ddc4e517834 411 Pfam PF00294 pfkB family carbohydrate kinase 28 123 5.3E-19 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB SMALA_RS24500 ddd643ee952c6500db1d3ddc4e517834 411 Gene3D G3DSA:3.40.1190.20 26 383 1.9E-62 T 29-03-2018 IPR029056 Ribokinase-like SMALA_RS10420 7ebe1431ed0b73ba041271b7b284b9d1 241 Pfam PF01553 Acyltransferase 17 147 6.6E-21 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SMALA_RS10420 7ebe1431ed0b73ba041271b7b284b9d1 241 SUPERFAMILY SSF69593 10 218 5.75E-50 T 29-03-2018 SMALA_RS10420 7ebe1431ed0b73ba041271b7b284b9d1 241 SMART SM00563 29 150 2.8E-34 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SMALA_RS10420 7ebe1431ed0b73ba041271b7b284b9d1 241 Gene3D G3DSA:3.40.1130.10 4 226 1.3E-56 T 29-03-2018 SMALA_RS14335 c92c76a53b830d3ecd8db9b143bc45ba 300 SUPERFAMILY SSF47413 29 82 5.63E-10 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS14335 c92c76a53b830d3ecd8db9b143bc45ba 300 SMART SM00530 11 83 1.7E-7 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS14335 c92c76a53b830d3ecd8db9b143bc45ba 300 Gene3D G3DSA:1.10.260.40 1 86 5.0E-14 T 29-03-2018 SMALA_RS14335 c92c76a53b830d3ecd8db9b143bc45ba 300 Pfam PF13560 Helix-turn-helix domain 8 83 6.5E-13 T 29-03-2018 SMALA_RS00665 2e06676a689ca7f50f9ff15593e039da 591 SMART SM00331 236 460 2.5E-33 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS00665 2e06676a689ca7f50f9ff15593e039da 591 SMART SM00065 66 215 6.6E-7 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS00665 2e06676a689ca7f50f9ff15593e039da 591 Gene3D G3DSA:3.30.565.10 464 590 2.8E-7 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS00665 2e06676a689ca7f50f9ff15593e039da 591 SUPERFAMILY SSF81606 243 401 3.53E-8 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS00665 2e06676a689ca7f50f9ff15593e039da 591 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 263 459 9.3E-50 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS00665 2e06676a689ca7f50f9ff15593e039da 591 SUPERFAMILY SSF55781 68 213 2.4E-19 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS00665 2e06676a689ca7f50f9ff15593e039da 591 Gene3D G3DSA:3.60.40.10 216 462 6.8E-38 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS00665 2e06676a689ca7f50f9ff15593e039da 591 Pfam PF13185 GAF domain 66 206 2.3E-12 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS00665 2e06676a689ca7f50f9ff15593e039da 591 Gene3D G3DSA:3.30.450.40 47 215 2.0E-25 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS34880 020a419c7c64ec47ce023ceda5629835 188 Hamap MF_00163 Peptide deformylase [def]. 12 175 29.41 T 29-03-2018 IPR023635 Peptide deformylase SMALA_RS34880 020a419c7c64ec47ce023ceda5629835 188 Gene3D G3DSA:3.90.45.10 7 180 3.8E-61 T 29-03-2018 IPR023635 Peptide deformylase SMALA_RS34880 020a419c7c64ec47ce023ceda5629835 188 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 20 168 7.9E-41 T 29-03-2018 IPR023635 Peptide deformylase SMALA_RS34880 020a419c7c64ec47ce023ceda5629835 188 PIRSF PIRSF004749 6 177 7.8E-44 T 29-03-2018 IPR023635 Peptide deformylase SMALA_RS34880 020a419c7c64ec47ce023ceda5629835 188 Pfam PF01327 Polypeptide deformylase 16 164 1.1E-46 T 29-03-2018 IPR023635 Peptide deformylase SMALA_RS34880 020a419c7c64ec47ce023ceda5629835 188 SUPERFAMILY SSF56420 11 171 7.85E-56 T 29-03-2018 IPR023635 Peptide deformylase SMALA_RS34880 020a419c7c64ec47ce023ceda5629835 188 PRINTS PR01576 Peptide deformylase signature 43 72 3.2E-33 T 29-03-2018 IPR023635 Peptide deformylase SMALA_RS34880 020a419c7c64ec47ce023ceda5629835 188 PRINTS PR01576 Peptide deformylase signature 114 132 3.2E-33 T 29-03-2018 IPR023635 Peptide deformylase SMALA_RS34880 020a419c7c64ec47ce023ceda5629835 188 PRINTS PR01576 Peptide deformylase signature 133 162 3.2E-33 T 29-03-2018 IPR023635 Peptide deformylase SMALA_RS34880 020a419c7c64ec47ce023ceda5629835 188 PRINTS PR01576 Peptide deformylase signature 102 113 3.2E-33 T 29-03-2018 IPR023635 Peptide deformylase SMALA_RS36655 f29583c796b28ceca2a5cf69e84a8854 369 SUPERFAMILY SSF81606 154 362 2.2E-8 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS36655 f29583c796b28ceca2a5cf69e84a8854 369 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 169 364 2.7E-38 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS36655 f29583c796b28ceca2a5cf69e84a8854 369 SMART SM00331 141 364 5.0E-31 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS36655 f29583c796b28ceca2a5cf69e84a8854 369 Gene3D G3DSA:3.60.40.10 105 367 8.3E-28 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS30020 88f8038b33951212e13ca5d6688fe58c 473 SUPERFAMILY SSF53244 322 466 1.83E-41 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 SMALA_RS30020 88f8038b33951212e13ca5d6688fe58c 473 Pfam PF08245 Mur ligase middle domain 117 302 7.0E-23 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMALA_RS30020 88f8038b33951212e13ca5d6688fe58c 473 Pfam PF02875 Mur ligase family, glutamate ligase domain 323 408 7.7E-19 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 SMALA_RS30020 88f8038b33951212e13ca5d6688fe58c 473 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 15 464 3.4E-138 T 29-03-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMALA_RS30020 88f8038b33951212e13ca5d6688fe58c 473 SUPERFAMILY SSF51984 13 100 1.83E-24 T 29-03-2018 SMALA_RS30020 88f8038b33951212e13ca5d6688fe58c 473 Pfam PF01225 Mur ligase family, catalytic domain 15 111 4.1E-27 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 SMALA_RS30020 88f8038b33951212e13ca5d6688fe58c 473 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 11 470 38.178 T 29-03-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMALA_RS30020 88f8038b33951212e13ca5d6688fe58c 473 Gene3D G3DSA:3.90.190.20 324 473 3.5E-37 T 29-03-2018 SMALA_RS30020 88f8038b33951212e13ca5d6688fe58c 473 SUPERFAMILY SSF53623 98 320 1.53E-55 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMALA_RS30020 88f8038b33951212e13ca5d6688fe58c 473 Gene3D G3DSA:3.40.50.720 13 100 2.2E-16 T 29-03-2018 SMALA_RS30020 88f8038b33951212e13ca5d6688fe58c 473 Gene3D G3DSA:3.40.1190.10 101 323 9.9E-45 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMALA_RS35685 b05d329384d2087278c4a006c7f8b620 263 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 132 160 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMALA_RS35685 b05d329384d2087278c4a006c7f8b620 263 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 181 1.7E-4 T 29-03-2018 SMALA_RS35685 b05d329384d2087278c4a006c7f8b620 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 2.2E-15 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS35685 b05d329384d2087278c4a006c7f8b620 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 2.2E-15 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS35685 b05d329384d2087278c4a006c7f8b620 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 183 2.2E-15 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS35685 b05d329384d2087278c4a006c7f8b620 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 164 2.2E-15 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS35685 b05d329384d2087278c4a006c7f8b620 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 119 135 2.2E-15 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS35685 b05d329384d2087278c4a006c7f8b620 263 Gene3D G3DSA:3.40.50.720 1 236 6.9E-51 T 29-03-2018 SMALA_RS35685 b05d329384d2087278c4a006c7f8b620 263 Pfam PF00106 short chain dehydrogenase 7 185 1.3E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS35685 b05d329384d2087278c4a006c7f8b620 263 SUPERFAMILY SSF51735 1 229 1.14E-55 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS12550 e7d144a2c2a0a79e829d26007948e987 438 PRINTS PR00149 Fumarate lyase superfamily signature 93 111 1.0E-18 T 29-03-2018 IPR000362 Fumarate lyase family SMALA_RS12550 e7d144a2c2a0a79e829d26007948e987 438 PRINTS PR00149 Fumarate lyase superfamily signature 138 156 1.0E-18 T 29-03-2018 IPR000362 Fumarate lyase family SMALA_RS12550 e7d144a2c2a0a79e829d26007948e987 438 PRINTS PR00149 Fumarate lyase superfamily signature 231 258 1.0E-18 T 29-03-2018 IPR000362 Fumarate lyase family SMALA_RS12550 e7d144a2c2a0a79e829d26007948e987 438 PRINTS PR00149 Fumarate lyase superfamily signature 273 289 1.0E-18 T 29-03-2018 IPR000362 Fumarate lyase family SMALA_RS12550 e7d144a2c2a0a79e829d26007948e987 438 Pfam PF00206 Lyase 43 295 1.3E-32 T 29-03-2018 IPR022761 Fumarate lyase, N-terminal SMALA_RS12550 e7d144a2c2a0a79e829d26007948e987 438 TIGRFAM TIGR02426 protocat_pcaB: 3-carboxy-cis,cis-muconate cycloisomerase 5 346 5.5E-117 T 29-03-2018 IPR012789 3-carboxy-cis,cis-muconate cycloisomerase GO:0019619|GO:0047472 KEGG: 00362+5.5.1.2 SMALA_RS12550 e7d144a2c2a0a79e829d26007948e987 438 SMART SM00998 361 434 1.3E-15 T 29-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SMALA_RS12550 e7d144a2c2a0a79e829d26007948e987 438 ProSitePatterns PS00163 Fumarate lyases signature. 273 282 - T 29-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 SMALA_RS12550 e7d144a2c2a0a79e829d26007948e987 438 PRINTS PR00145 Argininosuccinate lyase family signature 273 289 4.0E-6 T 29-03-2018 SMALA_RS12550 e7d144a2c2a0a79e829d26007948e987 438 PRINTS PR00145 Argininosuccinate lyase family signature 133 153 4.0E-6 T 29-03-2018 SMALA_RS12550 e7d144a2c2a0a79e829d26007948e987 438 PRINTS PR00145 Argininosuccinate lyase family signature 193 209 4.0E-6 T 29-03-2018 SMALA_RS12550 e7d144a2c2a0a79e829d26007948e987 438 Pfam PF10397 Adenylosuccinate lyase C-terminus 362 433 9.1E-14 T 29-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SMALA_RS12550 e7d144a2c2a0a79e829d26007948e987 438 SUPERFAMILY SSF48557 7 435 2.36E-82 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 SMALA_RS12550 e7d144a2c2a0a79e829d26007948e987 438 Gene3D G3DSA:1.10.40.30 373 434 1.8E-20 T 29-03-2018 SMALA_RS12550 e7d144a2c2a0a79e829d26007948e987 438 Gene3D G3DSA:1.20.200.10 98 372 4.5E-88 T 29-03-2018 SMALA_RS12550 e7d144a2c2a0a79e829d26007948e987 438 Gene3D G3DSA:1.10.275.10 2 97 3.9E-6 T 29-03-2018 IPR024083 Fumarase/histidase, N-terminal SMALA_RS38820 9f307a96457086332b4e8c2391c932a2 255 Pfam PF00486 Transcriptional regulatory protein, C terminal 157 239 2.5E-21 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS38820 9f307a96457086332b4e8c2391c932a2 255 Gene3D G3DSA:1.10.10.10 128 246 7.0E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS38820 9f307a96457086332b4e8c2391c932a2 255 Pfam PF00072 Response regulator receiver domain 12 121 1.8E-23 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS38820 9f307a96457086332b4e8c2391c932a2 255 Gene3D G3DSA:3.40.50.2300 2 127 3.4E-31 T 29-03-2018 SMALA_RS38820 9f307a96457086332b4e8c2391c932a2 255 SMART SM00448 10 121 2.7E-33 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS38820 9f307a96457086332b4e8c2391c932a2 255 SUPERFAMILY SSF52172 11 189 1.29E-35 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS38820 9f307a96457086332b4e8c2391c932a2 255 SMART SM00862 157 239 4.9E-21 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS25640 928f22655824727911c8126b7fb403c1 541 SUPERFAMILY SSF53850 30 535 2.71E-85 T 29-03-2018 SMALA_RS25640 928f22655824727911c8126b7fb403c1 541 Gene3D G3DSA:3.10.105.10 314 513 3.9E-29 T 29-03-2018 SMALA_RS25640 928f22655824727911c8126b7fb403c1 541 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 79 460 1.3E-47 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain SMALA_RS25640 928f22655824727911c8126b7fb403c1 541 Gene3D G3DSA:3.40.190.10 201 313 2.1E-21 T 29-03-2018 SMALA_RS25640 928f22655824727911c8126b7fb403c1 541 PIRSF PIRSF002741 3 533 1.2E-52 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 SMALA_RS25640 928f22655824727911c8126b7fb403c1 541 Gene3D G3DSA:3.90.76.10 43 200 4.8E-28 T 29-03-2018 SMALA_RS18560 236881995119f0c87aa4963af3502af0 388 Pfam PF00437 Type II/IV secretion system protein 59 334 2.7E-79 T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 SMALA_RS18560 236881995119f0c87aa4963af3502af0 388 TIGRFAM TIGR03819 heli_sec_ATPase: helicase/secretion neighborhood ATPase 9 345 2.0E-157 T 29-03-2018 IPR022399 Helicase/secretion neighbourhood ATPase SMALA_RS18560 236881995119f0c87aa4963af3502af0 388 Gene3D G3DSA:3.40.50.300 167 340 8.1E-14 T 29-03-2018 SMALA_RS18560 236881995119f0c87aa4963af3502af0 388 Gene3D G3DSA:3.30.450.90 55 159 5.6E-36 T 29-03-2018 SMALA_RS18560 236881995119f0c87aa4963af3502af0 388 SUPERFAMILY SSF52540 44 355 3.55E-51 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS16960 d6ac03f4ff79e5e477fcc119e832daa4 342 Pfam PF00877 NlpC/P60 family 242 330 2.6E-25 T 29-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain SMALA_RS16960 d6ac03f4ff79e5e477fcc119e832daa4 342 Gene3D G3DSA:3.90.1720.10 132 274 1.5E-21 T 29-03-2018 SMALA_RS16960 d6ac03f4ff79e5e477fcc119e832daa4 342 Gene3D G3DSA:2.30.260.10 275 337 2.1E-19 T 29-03-2018 SMALA_RS16960 d6ac03f4ff79e5e477fcc119e832daa4 342 SUPERFAMILY SSF54001 223 334 5.89E-41 T 29-03-2018 SMALA_RS04540 33f5941da53a97e89face534589af562 265 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 97 250 2.7E-9 T 29-03-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 SMALA_RS04540 33f5941da53a97e89face534589af562 265 Pfam PF00440 Bacterial regulatory proteins, tetR family 38 79 2.3E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS04540 33f5941da53a97e89face534589af562 265 SUPERFAMILY SSF46689 27 86 6.31E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS04540 33f5941da53a97e89face534589af562 265 SUPERFAMILY SSF48498 99 253 1.67E-18 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS04540 33f5941da53a97e89face534589af562 265 Gene3D G3DSA:1.10.10.60 71 105 9.6E-8 T 29-03-2018 SMALA_RS04540 33f5941da53a97e89face534589af562 265 Gene3D G3DSA:1.10.357.10 106 264 4.6E-33 T 29-03-2018 SMALA_RS04540 33f5941da53a97e89face534589af562 265 Gene3D G3DSA:1.10.10.60 2 70 2.3E-15 T 29-03-2018 SMALA_RS10200 586883ecfeaa3c72e9313605bcdec6bf 246 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 16 243 1.9E-70 T 29-03-2018 IPR003730 Multi-copper polyphenol oxidoreductase SMALA_RS10200 586883ecfeaa3c72e9313605bcdec6bf 246 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 21 244 2.3E-46 T 29-03-2018 IPR003730 Multi-copper polyphenol oxidoreductase SMALA_RS10200 586883ecfeaa3c72e9313605bcdec6bf 246 SUPERFAMILY SSF64438 8 244 1.08E-72 T 29-03-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic SMALA_RS10200 586883ecfeaa3c72e9313605bcdec6bf 246 Gene3D G3DSA:3.60.140.10 1 246 2.6E-84 T 29-03-2018 SMALA_RS23895 58ee760d625b9c12115ef79661f81806 205 Gene3D G3DSA:1.10.357.10 64 202 5.6E-21 T 29-03-2018 SMALA_RS23895 58ee760d625b9c12115ef79661f81806 205 SUPERFAMILY SSF48498 81 195 1.14E-16 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS23895 58ee760d625b9c12115ef79661f81806 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 1.1E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS23895 58ee760d625b9c12115ef79661f81806 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 1.1E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS23895 58ee760d625b9c12115ef79661f81806 205 SUPERFAMILY SSF46689 5 84 1.08E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS23895 58ee760d625b9c12115ef79661f81806 205 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 85 195 4.6E-14 T 29-03-2018 SMALA_RS23895 58ee760d625b9c12115ef79661f81806 205 Gene3D G3DSA:1.10.10.60 1 63 2.8E-17 T 29-03-2018 SMALA_RS23895 58ee760d625b9c12115ef79661f81806 205 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 63 1.1E-13 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS29015 9d082a3fce26d1a825019d998a0ee788 721 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 23 362 4.1E-68 T 29-03-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 SMALA_RS29015 9d082a3fce26d1a825019d998a0ee788 721 SMART SM00490 265 346 7.0E-22 T 29-03-2018 IPR001650 Helicase, C-terminal SMALA_RS29015 9d082a3fce26d1a825019d998a0ee788 721 Gene3D G3DSA:3.40.50.2020 574 721 3.0E-14 T 29-03-2018 SMALA_RS29015 9d082a3fce26d1a825019d998a0ee788 721 Gene3D G3DSA:3.40.50.300 234 380 3.7E-26 T 29-03-2018 SMALA_RS29015 9d082a3fce26d1a825019d998a0ee788 721 SUPERFAMILY SSF53271 656 717 7.87E-10 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like SMALA_RS29015 9d082a3fce26d1a825019d998a0ee788 721 Gene3D G3DSA:3.40.50.300 5 209 8.6E-28 T 29-03-2018 SMALA_RS29015 9d082a3fce26d1a825019d998a0ee788 721 Pfam PF16124 RecQ zinc-binding 446 488 7.3E-6 T 29-03-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain SMALA_RS29015 9d082a3fce26d1a825019d998a0ee788 721 SUPERFAMILY SSF52540 35 355 6.21E-50 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS29015 9d082a3fce26d1a825019d998a0ee788 721 Gene3D G3DSA:1.10.10.10 424 573 7.8E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS29015 9d082a3fce26d1a825019d998a0ee788 721 Pfam PF00271 Helicase conserved C-terminal domain 252 345 1.0E-13 T 29-03-2018 IPR001650 Helicase, C-terminal SMALA_RS29015 9d082a3fce26d1a825019d998a0ee788 721 Pfam PF00270 DEAD/DEAH box helicase 30 196 1.3E-16 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 SMALA_RS29015 9d082a3fce26d1a825019d998a0ee788 721 SMART SM00487 23 218 4.4E-21 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain SMALA_RS20750 ae130b634609dc39f3225b77b35d2b29 340 SUPERFAMILY SSF51569 5 336 1.61E-93 T 29-03-2018 SMALA_RS20750 ae130b634609dc39f3225b77b35d2b29 340 Gene3D G3DSA:3.20.20.70 1 340 5.2E-100 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS20750 ae130b634609dc39f3225b77b35d2b29 340 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 10 337 3.1E-69 T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 SMALA_RS20750 ae130b634609dc39f3225b77b35d2b29 340 TIGRFAM TIGR01520 FruBisAldo_II_A: fructose-bisphosphate aldolase, class II 3 336 3.9E-126 T 29-03-2018 IPR006411 Fructose-bisphosphate aldolase, class II, yeast/E. coli subtype GO:0004332|GO:0006096 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 SMALA_RS20750 ae130b634609dc39f3225b77b35d2b29 340 Pfam PF01116 Fructose-bisphosphate aldolase class-II 9 336 4.5E-77 T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 SMALA_RS20750 ae130b634609dc39f3225b77b35d2b29 340 PIRSF PIRSF001359 6 338 1.7E-61 T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 SMALA_RS20750 ae130b634609dc39f3225b77b35d2b29 340 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 86 97 - T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 Gene3D G3DSA:3.40.50.10090 1011 1153 0.32 T 29-03-2018 SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 SUPERFAMILY SSF52151 3706 3835 1.88E-69 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 SUPERFAMILY SSF52151 3899 3998 1.88E-69 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 Pfam PF00698 Acyl transferase domain 576 894 9.4E-95 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 Pfam PF00698 Acyl transferase domain 3708 4025 5.2E-89 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 Pfam PF00698 Acyl transferase domain 5499 5815 7.9E-56 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 Pfam PF00698 Acyl transferase domain 2151 2432 5.8E-53 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 SUPERFAMILY SSF53901 1611 1988 3.89E-101 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 Gene3D G3DSA:1.10.1200.10 3056 3154 1.0E-20 T 29-03-2018 SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 SUPERFAMILY SSF51735 5917 6128 2.32E-43 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 SUPERFAMILY SSF53901 3166 3534 1.18E-106 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 Pfam PF08990 Erythronolide synthase docking 2 27 1.2E-10 T 29-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 3332 3348 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 Pfam PF14765 Polyketide synthase dehydratase 4074 4354 3.6E-48 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 SMART SM00826 4074 4240 8.3E-76 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 292 409 7.8E-44 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1872 1990 1.5E-44 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 3427 3544 4.8E-44 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 5220 5338 7.2E-42 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 SUPERFAMILY SSF52151 2332 2440 2.3E-74 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 SUPERFAMILY SSF52151 2148 2270 2.3E-74 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 5341 5462 1.2E-13 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 412 539 1.1E-16 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1993 2105 8.3E-13 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 3547 3671 3.9E-15 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3169 3419 4.3E-94 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1614 1864 2.4E-90 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 284 1.4E-93 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4962 5212 1.7E-94 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 Gene3D G3DSA:3.40.47.10 1606 1876 7.5E-85 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 Gene3D G3DSA:3.40.47.10 4960 5224 1.3E-90 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 Gene3D G3DSA:3.40.47.10 3161 3431 2.1E-88 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 Gene3D G3DSA:3.40.47.10 26 296 1.9E-89 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4889 4904 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 Gene3D G3DSA:1.10.1200.10 6424 6522 1.0E-19 T 29-03-2018 SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 Gene3D G3DSA:1.10.1200.10 4855 4959 1.8E-18 T 29-03-2018 SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 SUPERFAMILY SSF51735 4360 4558 2.91E-37 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 SUPERFAMILY SSF53901 31 407 2.89E-104 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 Gene3D G3DSA:3.40.47.10 299 460 7.2E-63 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 Gene3D G3DSA:3.40.47.10 3434 3595 1.9E-62 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 Gene3D G3DSA:3.40.47.10 5227 5389 4.7E-60 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 Gene3D G3DSA:3.40.47.10 1879 2041 9.1E-63 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 SUPERFAMILY SSF52151 574 703 8.89E-71 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 SUPERFAMILY SSF52151 767 864 8.89E-71 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 SUPERFAMILY SSF47336 3068 3183 8.9E-24 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 Gene3D G3DSA:3.40.366.10 573 711 1.4E-46 T 29-03-2018 SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 Gene3D G3DSA:3.40.366.10 2147 2284 6.4E-44 T 29-03-2018 SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 Gene3D G3DSA:3.40.366.10 3706 3843 2.5E-41 T 29-03-2018 SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 Gene3D G3DSA:3.40.366.10 5495 5632 4.6E-42 T 29-03-2018 SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 SUPERFAMILY SSF51735 991 1204 1.41E-51 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6142 6321 5.9E-60 T 29-03-2018 SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4574 4754 3.1E-56 T 29-03-2018 SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2784 2963 3.1E-55 T 29-03-2018 SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1218 1397 1.9E-50 T 29-03-2018 SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 Gene3D G3DSA:3.40.366.10 759 878 1.1E-28 T 29-03-2018 SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 Gene3D G3DSA:3.40.366.10 3892 4014 5.0E-29 T 29-03-2018 SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 SUPERFAMILY SSF51735 4571 4810 4.88E-42 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1535 1550 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 Gene3D G3DSA:3.10.129.10 4076 4195 2.8E-5 T 29-03-2018 SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 SUPERFAMILY SSF53901 4958 5328 5.62E-102 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 Gene3D G3DSA:3.40.366.10 5676 5789 2.3E-29 T 29-03-2018 SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 ProSitePatterns PS00012 Phosphopantetheine attachment site. 6458 6473 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3100 3115 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 SUPERFAMILY SSF47336 1501 1629 3.53E-21 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 SUPERFAMILY SSF47336 6423 6509 2.36E-20 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 SMART SM00825 Beta-ketoacyl synthase 4964 5391 6.6E-225 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 SMART SM00825 Beta-ketoacyl synthase 1616 2043 2.5E-218 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 SMART SM00825 Beta-ketoacyl synthase 3171 3597 6.0E-228 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 SMART SM00825 Beta-ketoacyl synthase 36 462 3.3E-229 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 SUPERFAMILY SSF55048 701 766 9.68E-14 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 Gene3D G3DSA:1.10.1200.10 1482 1588 1.8E-18 T 29-03-2018 SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1777 1793 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 SUPERFAMILY SSF51735 2559 2771 1.93E-43 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 SUPERFAMILY SSF55048 3833 3898 1.57E-13 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 Pfam PF00550 Phosphopantetheine attachment site 3075 3141 3.4E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 Pfam PF00550 Phosphopantetheine attachment site 6433 6499 9.1E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 Pfam PF00550 Phosphopantetheine attachment site 4865 4930 4.3E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 Pfam PF00550 Phosphopantetheine attachment site 1511 1576 9.4E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 SUPERFAMILY SSF47336 4855 4977 4.71E-21 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 Gene3D G3DSA:3.40.366.10 2330 2446 1.5E-32 T 29-03-2018 SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 Gene3D G3DSA:3.30.70.250 712 758 3.0E-19 T 29-03-2018 SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 Gene3D G3DSA:3.30.70.250 2285 2329 3.7E-17 T 29-03-2018 SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 Gene3D G3DSA:3.30.70.250 3844 3891 2.7E-18 T 29-03-2018 SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 Gene3D G3DSA:3.30.70.250 5633 5675 4.1E-18 T 29-03-2018 SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 Pfam PF08659 KR domain 4574 4753 6.0E-54 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 Pfam PF08659 KR domain 2784 2962 4.7E-58 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 Pfam PF08659 KR domain 6142 6320 8.2E-60 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 Pfam PF08659 KR domain 1218 1395 2.9E-59 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 SUPERFAMILY SSF51735 2780 3029 3.36E-49 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 SUPERFAMILY SSF51735 1216 1452 1.73E-46 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 SUPERFAMILY SSF51735 6139 6376 4.77E-50 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 SUPERFAMILY SSF52151 5686 5782 1.07E-72 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 SUPERFAMILY SSF52151 5495 5622 1.07E-72 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 5125 5141 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 SMART SM01294 1509 1576 3.7E-5 T 29-03-2018 SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 SMART SM01294 6432 6499 1.0E-5 T 29-03-2018 SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 SMART SM01294 4863 4930 3.1E-6 T 29-03-2018 SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 SMART SM01294 3074 3141 3.8E-6 T 29-03-2018 SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 3709 4007 2.3E-128 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 5499 5796 1.1E-124 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2151 2445 2.0E-128 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 577 875 6.1E-129 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 SMART SM00823 Phosphopantetheine attachment site 3073 3145 2.7E-32 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 SMART SM00823 Phosphopantetheine attachment site 1508 1580 5.9E-33 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 SMART SM00823 Phosphopantetheine attachment site 6431 6503 2.6E-30 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 SMART SM00823 Phosphopantetheine attachment site 4862 4934 2.3E-31 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 SUPERFAMILY SSF55048 5621 5685 1.23E-11 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 197 213 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 Gene3D G3DSA:3.40.50.720 6134 6395 3.1E-53 T 29-03-2018 SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 Gene3D G3DSA:3.40.50.720 2776 3037 2.6E-55 T 29-03-2018 SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 Gene3D G3DSA:3.40.50.720 4568 4828 4.5E-44 T 29-03-2018 SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 Gene3D G3DSA:3.40.50.720 1210 1471 4.0E-53 T 29-03-2018 SMALA_RS01605 78c8223f1064fd69331901b3f8dde9b2 6589 SUPERFAMILY SSF55048 2275 2339 1.44E-10 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS03990 a3076fb642b1fdf10310483c58243aa3 305 Gene3D G3DSA:1.10.3720.10 18 292 3.3E-43 T 29-03-2018 SMALA_RS03990 a3076fb642b1fdf10310483c58243aa3 305 SUPERFAMILY SSF161098 25 305 1.96E-68 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS03990 a3076fb642b1fdf10310483c58243aa3 305 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 105 295 5.6E-19 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS41860 d957742cf2474490b616122136bb4a08 200 Pfam PF07883 Cupin domain 129 187 8.8E-10 T 29-03-2018 IPR013096 Cupin 2, conserved barrel SMALA_RS41860 d957742cf2474490b616122136bb4a08 200 Pfam PF13560 Helix-turn-helix domain 21 78 1.0E-14 T 29-03-2018 SMALA_RS41860 d957742cf2474490b616122136bb4a08 200 SUPERFAMILY SSF47413 18 86 3.94E-17 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS41860 d957742cf2474490b616122136bb4a08 200 Gene3D G3DSA:1.10.260.40 11 77 2.0E-17 T 29-03-2018 SMALA_RS41860 d957742cf2474490b616122136bb4a08 200 Gene3D G3DSA:2.60.120.10 78 198 2.2E-14 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SMALA_RS41860 d957742cf2474490b616122136bb4a08 200 SMART SM00530 24 79 1.1E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS41860 d957742cf2474490b616122136bb4a08 200 SUPERFAMILY SSF51182 77 188 1.28E-18 T 29-03-2018 IPR011051 RmlC-like cupin domain SMALA_RS20865 ea0e4a1b6e9a15364983a044175cab39 484 Gene3D G3DSA:3.50.50.60 2 471 4.9E-26 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS20865 ea0e4a1b6e9a15364983a044175cab39 484 SUPERFAMILY SSF51905 2 303 1.3E-33 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS20865 ea0e4a1b6e9a15364983a044175cab39 484 SUPERFAMILY SSF51905 427 459 1.3E-33 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS20865 ea0e4a1b6e9a15364983a044175cab39 484 PRINTS PR00419 Adrenodoxin reductase family signature 3 25 2.5E-6 T 29-03-2018 SMALA_RS20865 ea0e4a1b6e9a15364983a044175cab39 484 PRINTS PR00419 Adrenodoxin reductase family signature 26 39 2.5E-6 T 29-03-2018 SMALA_RS20865 ea0e4a1b6e9a15364983a044175cab39 484 Pfam PF13450 NAD(P)-binding Rossmann-like domain 6 70 1.6E-9 T 29-03-2018 SMALA_RS36035 dc086021643a787221b48d362d454029 446 Pfam PF00107 Zinc-binding dehydrogenase 237 381 2.8E-33 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMALA_RS36035 dc086021643a787221b48d362d454029 446 Gene3D G3DSA:3.90.180.10 5 417 1.5E-64 T 29-03-2018 SMALA_RS36035 dc086021643a787221b48d362d454029 446 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 111 191 3.7E-7 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS36035 dc086021643a787221b48d362d454029 446 SMART SM00829 49 416 3.6E-10 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS36035 dc086021643a787221b48d362d454029 446 TIGRFAM TIGR01751 crot-CoA-red: crotonyl-CoA carboxylase/reductase 32 429 8.7E-174 T 29-03-2018 IPR010085 Crotonyl-CoA reductase GO:0043880 KEGG: 00650+1.3.1.86 SMALA_RS36035 dc086021643a787221b48d362d454029 446 SUPERFAMILY SSF51735 196 386 1.97E-31 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS36035 dc086021643a787221b48d362d454029 446 SUPERFAMILY SSF50129 43 230 3.47E-29 T 29-03-2018 IPR011032 GroES-like SMALA_RS10985 ede72645f890dce8cca5f969ad6f574c 337 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS10985 ede72645f890dce8cca5f969ad6f574c 337 SMART SM00382 38 229 1.4E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS10985 ede72645f890dce8cca5f969ad6f574c 337 SUPERFAMILY SSF52540 14 235 3.34E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS10985 ede72645f890dce8cca5f969ad6f574c 337 Gene3D G3DSA:3.40.50.300 11 252 6.6E-62 T 29-03-2018 SMALA_RS10985 ede72645f890dce8cca5f969ad6f574c 337 Pfam PF00005 ABC transporter 30 172 1.0E-26 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS10985 ede72645f890dce8cca5f969ad6f574c 337 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 21 320 1.1E-112 T 29-03-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 SMALA_RS10985 ede72645f890dce8cca5f969ad6f574c 337 Pfam PF13732 Domain of unknown function (DUF4162) 226 318 9.5E-7 T 29-03-2018 IPR025302 Domain of unknown function DUF4162 SMALA_RS22775 e72d00e2cd86ad84d9d2ad381c22c2a2 348 Gene3D G3DSA:3.20.20.70 4 72 2.7E-4 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS22775 e72d00e2cd86ad84d9d2ad381c22c2a2 348 Gene3D G3DSA:3.90.1200.10 73 300 3.2E-5 T 29-03-2018 SMALA_RS22775 e72d00e2cd86ad84d9d2ad381c22c2a2 348 SUPERFAMILY SSF56112 104 258 4.52E-6 T 29-03-2018 IPR011009 Protein kinase-like domain SMALA_RS22775 e72d00e2cd86ad84d9d2ad381c22c2a2 348 Pfam PF13186 Iron-sulfur cluster-binding domain 21 71 6.2E-6 T 29-03-2018 IPR023885 4Fe4S-binding SPASM domain SMALA_RS19300 1729ffa6b02d93fe3904c060e042ae88 166 SUPERFAMILY SSF110087 48 159 6.67E-31 T 29-03-2018 IPR007410 Copper chaperone PCuAC SMALA_RS19300 1729ffa6b02d93fe3904c060e042ae88 166 Pfam PF04314 Copper chaperone PCu(A)C 51 153 1.2E-28 T 29-03-2018 IPR007410 Copper chaperone PCuAC SMALA_RS19300 1729ffa6b02d93fe3904c060e042ae88 166 Gene3D G3DSA:3.40.190.10 7 142 2.8E-6 T 29-03-2018 SMALA_RS28025 eacdb3b0b2f052dcbb81aecd2e523304 311 SUPERFAMILY SSF57716 236 285 1.03E-15 T 29-03-2018 SMALA_RS28025 eacdb3b0b2f052dcbb81aecd2e523304 311 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 285 41.687 T 29-03-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 SMALA_RS28025 eacdb3b0b2f052dcbb81aecd2e523304 311 ProSitePatterns PS01242 Zinc finger FPG-type signature. 260 284 - T 29-03-2018 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 SMALA_RS28025 eacdb3b0b2f052dcbb81aecd2e523304 311 SMART SM00898 2 125 6.1E-47 T 29-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 SMALA_RS28025 eacdb3b0b2f052dcbb81aecd2e523304 311 SMART SM01232 144 236 1.5E-44 T 29-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 SMALA_RS28025 eacdb3b0b2f052dcbb81aecd2e523304 311 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 284 6.2E-87 T 29-03-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 SMALA_RS28025 eacdb3b0b2f052dcbb81aecd2e523304 311 Pfam PF06827 Zinc finger found in FPG and IleRS 258 284 1.1E-4 T 29-03-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 SMALA_RS28025 eacdb3b0b2f052dcbb81aecd2e523304 311 Gene3D G3DSA:3.20.190.10 2 133 3.2E-44 T 29-03-2018 SMALA_RS28025 eacdb3b0b2f052dcbb81aecd2e523304 311 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 2 123 1.8E-33 T 29-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 SMALA_RS28025 eacdb3b0b2f052dcbb81aecd2e523304 311 Gene3D G3DSA:1.10.8.50 146 300 1.1E-47 T 29-03-2018 SMALA_RS28025 eacdb3b0b2f052dcbb81aecd2e523304 311 SUPERFAMILY SSF46946 144 233 2.36E-27 T 29-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 SMALA_RS28025 eacdb3b0b2f052dcbb81aecd2e523304 311 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 144 231 7.8E-23 T 29-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 SMALA_RS28025 eacdb3b0b2f052dcbb81aecd2e523304 311 SUPERFAMILY SSF81624 2 153 2.49E-33 T 29-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 SMALA_RS19830 2e214d3bef84a8cbec604fa724c67910 216 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 46 60 3.2E-9 T 29-03-2018 SMALA_RS19830 2e214d3bef84a8cbec604fa724c67910 216 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 77 93 3.2E-9 T 29-03-2018 SMALA_RS19830 2e214d3bef84a8cbec604fa724c67910 216 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 5 188 1.2E-60 T 29-03-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 SMALA_RS19830 2e214d3bef84a8cbec604fa724c67910 216 PRINTS PR00097 Anthranilate synthase component II signature 102 110 1.5E-33 T 29-03-2018 SMALA_RS19830 2e214d3bef84a8cbec604fa724c67910 216 PRINTS PR00097 Anthranilate synthase component II signature 5 19 1.5E-33 T 29-03-2018 SMALA_RS19830 2e214d3bef84a8cbec604fa724c67910 216 PRINTS PR00097 Anthranilate synthase component II signature 122 134 1.5E-33 T 29-03-2018 SMALA_RS19830 2e214d3bef84a8cbec604fa724c67910 216 PRINTS PR00097 Anthranilate synthase component II signature 167 180 1.5E-33 T 29-03-2018 SMALA_RS19830 2e214d3bef84a8cbec604fa724c67910 216 PRINTS PR00097 Anthranilate synthase component II signature 49 58 1.5E-33 T 29-03-2018 SMALA_RS19830 2e214d3bef84a8cbec604fa724c67910 216 PRINTS PR00097 Anthranilate synthase component II signature 77 88 1.5E-33 T 29-03-2018 SMALA_RS19830 2e214d3bef84a8cbec604fa724c67910 216 Pfam PF00117 Glutamine amidotransferase class-I 7 190 3.1E-52 T 29-03-2018 IPR017926 Glutamine amidotransferase SMALA_RS19830 2e214d3bef84a8cbec604fa724c67910 216 PRINTS PR00096 Glutamine amidotransferase superfamily signature 49 58 5.4E-13 T 29-03-2018 SMALA_RS19830 2e214d3bef84a8cbec604fa724c67910 216 PRINTS PR00096 Glutamine amidotransferase superfamily signature 167 180 5.4E-13 T 29-03-2018 SMALA_RS19830 2e214d3bef84a8cbec604fa724c67910 216 PRINTS PR00096 Glutamine amidotransferase superfamily signature 77 88 5.4E-13 T 29-03-2018 SMALA_RS19830 2e214d3bef84a8cbec604fa724c67910 216 Gene3D G3DSA:3.40.50.880 3 194 2.6E-61 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS19830 2e214d3bef84a8cbec604fa724c67910 216 SUPERFAMILY SSF52317 3 191 9.76E-57 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS40855 b8d5b32147a9412432db732c36f09604 344 Gene3D G3DSA:3.40.50.2300 58 178 6.7E-35 T 29-03-2018 SMALA_RS40855 b8d5b32147a9412432db732c36f09604 344 Gene3D G3DSA:1.10.10.60 1 17 0.007 T 29-03-2018 SMALA_RS40855 b8d5b32147a9412432db732c36f09604 344 Gene3D G3DSA:1.10.260.40 18 57 1.7E-21 T 29-03-2018 SMALA_RS40855 b8d5b32147a9412432db732c36f09604 344 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 50 2.3E-14 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS40855 b8d5b32147a9412432db732c36f09604 344 Gene3D G3DSA:3.40.50.2300 179 309 5.9E-41 T 29-03-2018 SMALA_RS40855 b8d5b32147a9412432db732c36f09604 344 SUPERFAMILY SSF47413 2 61 1.13E-16 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS40855 b8d5b32147a9412432db732c36f09604 344 Pfam PF13377 Periplasmic binding protein-like domain 171 334 1.4E-36 T 29-03-2018 SMALA_RS40855 b8d5b32147a9412432db732c36f09604 344 SMART SM00354 3 73 3.5E-24 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS40855 b8d5b32147a9412432db732c36f09604 344 SUPERFAMILY SSF53822 63 336 1.38E-69 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SMALA_RS07125 4dc08b0c5608d07017aebf8af2648ead 1133 SUPERFAMILY SSF82171 407 667 1.41E-37 T 29-03-2018 SMALA_RS07125 4dc08b0c5608d07017aebf8af2648ead 1133 SUPERFAMILY SSF51556 751 1048 2.28E-34 T 29-03-2018 IPR032466 Metal-dependent hydrolase SMALA_RS07125 4dc08b0c5608d07017aebf8af2648ead 1133 Pfam PF07676 WD40-like Beta Propeller Repeat 140 177 5.5E-9 T 29-03-2018 IPR011659 WD40-like Beta Propeller SMALA_RS07125 4dc08b0c5608d07017aebf8af2648ead 1133 Pfam PF07676 WD40-like Beta Propeller Repeat 411 425 0.24 T 29-03-2018 IPR011659 WD40-like Beta Propeller SMALA_RS07125 4dc08b0c5608d07017aebf8af2648ead 1133 Pfam PF07676 WD40-like Beta Propeller Repeat 593 609 0.099 T 29-03-2018 IPR011659 WD40-like Beta Propeller SMALA_RS07125 4dc08b0c5608d07017aebf8af2648ead 1133 Pfam PF07676 WD40-like Beta Propeller Repeat 204 221 0.036 T 29-03-2018 IPR011659 WD40-like Beta Propeller SMALA_RS07125 4dc08b0c5608d07017aebf8af2648ead 1133 Pfam PF07676 WD40-like Beta Propeller Repeat 103 127 3.5E-5 T 29-03-2018 IPR011659 WD40-like Beta Propeller SMALA_RS07125 4dc08b0c5608d07017aebf8af2648ead 1133 Pfam PF07676 WD40-like Beta Propeller Repeat 455 473 0.0093 T 29-03-2018 IPR011659 WD40-like Beta Propeller SMALA_RS07125 4dc08b0c5608d07017aebf8af2648ead 1133 Gene3D G3DSA:2.140.10.30 33 207 3.9E-27 T 29-03-2018 SMALA_RS07125 4dc08b0c5608d07017aebf8af2648ead 1133 Gene3D G3DSA:2.140.10.30 287 505 7.4E-23 T 29-03-2018 SMALA_RS07125 4dc08b0c5608d07017aebf8af2648ead 1133 Gene3D G3DSA:2.30.40.10 689 766 1.7E-17 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS07125 4dc08b0c5608d07017aebf8af2648ead 1133 Gene3D G3DSA:2.120.10.30 506 688 7.6E-20 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like SMALA_RS07125 4dc08b0c5608d07017aebf8af2648ead 1133 Gene3D G3DSA:2.130.10.10 208 278 0.1 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMALA_RS07125 4dc08b0c5608d07017aebf8af2648ead 1133 Pfam PF01979 Amidohydrolase family 1013 1076 7.4E-12 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 SMALA_RS07125 4dc08b0c5608d07017aebf8af2648ead 1133 SUPERFAMILY SSF69304 65 277 9.81E-28 T 29-03-2018 SMALA_RS07125 4dc08b0c5608d07017aebf8af2648ead 1133 Gene3D G3DSA:3.20.20.140 767 1043 4.4E-30 T 29-03-2018 SMALA_RS07125 4dc08b0c5608d07017aebf8af2648ead 1133 SUPERFAMILY SSF51338 679 752 4.91E-17 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS07125 4dc08b0c5608d07017aebf8af2648ead 1133 SUPERFAMILY SSF51338 1047 1072 4.91E-17 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS03195 43cfa5fa22cf3b3f5ef99e7b27c61d11 352 Pfam PF13280 WYL domain 142 318 1.9E-37 T 29-03-2018 IPR026881 WYL domain SMALA_RS03195 43cfa5fa22cf3b3f5ef99e7b27c61d11 352 PIRSF PIRSF016838 2 58 1.7E-4 T 29-03-2018 IPR028349 Protein PafC SMALA_RS03195 43cfa5fa22cf3b3f5ef99e7b27c61d11 352 PIRSF PIRSF016838 72 326 6.3E-8 T 29-03-2018 IPR028349 Protein PafC SMALA_RS03195 43cfa5fa22cf3b3f5ef99e7b27c61d11 352 Pfam PF08279 HTH domain 8 62 1.6E-15 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 SMALA_RS03195 43cfa5fa22cf3b3f5ef99e7b27c61d11 352 SUPERFAMILY SSF46785 4 58 2.9E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS03195 43cfa5fa22cf3b3f5ef99e7b27c61d11 352 Gene3D G3DSA:1.10.10.10 2 72 2.4E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS37675 0a0ee7ef8eddf32d8481975d1206bab2 146 SMART SM00347 27 128 4.6E-24 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS37675 0a0ee7ef8eddf32d8481975d1206bab2 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 69 84 6.0E-8 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS37675 0a0ee7ef8eddf32d8481975d1206bab2 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 88 104 6.0E-8 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS37675 0a0ee7ef8eddf32d8481975d1206bab2 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 118 138 6.0E-8 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS37675 0a0ee7ef8eddf32d8481975d1206bab2 146 Gene3D G3DSA:1.10.10.10 2 143 2.5E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS37675 0a0ee7ef8eddf32d8481975d1206bab2 146 SUPERFAMILY SSF46785 8 140 1.24E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS37675 0a0ee7ef8eddf32d8481975d1206bab2 146 Pfam PF12802 MarR family 32 91 1.7E-11 T 29-03-2018 SMALA_RS27275 ab0d62e609c67df6289b842e5da65916 333 Pfam PF00704 Glycosyl hydrolases family 18 61 248 4.9E-9 T 29-03-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 SMALA_RS27275 ab0d62e609c67df6289b842e5da65916 333 SUPERFAMILY SSF51445 51 306 8.44E-19 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS27275 ab0d62e609c67df6289b842e5da65916 333 Gene3D G3DSA:3.20.20.80 46 319 5.3E-27 T 29-03-2018 SMALA_RS34280 567a4c3de8f2c904abfe8f72bf2551c1 291 SMART SM00530 21 77 2.1E-5 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS34280 567a4c3de8f2c904abfe8f72bf2551c1 291 Pfam PF13560 Helix-turn-helix domain 18 79 1.3E-14 T 29-03-2018 SMALA_RS34280 567a4c3de8f2c904abfe8f72bf2551c1 291 SUPERFAMILY SSF47413 14 74 3.64E-9 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS34280 567a4c3de8f2c904abfe8f72bf2551c1 291 Gene3D G3DSA:1.10.3100.10 13 167 2.8E-15 T 29-03-2018 IPR027910 YdiL-like domain SMALA_RS26065 c9081a48f38b8deace9028d3e588197d 227 Gene3D G3DSA:3.60.160.10 12 226 8.2E-47 T 29-03-2018 IPR002838 Mitochondrial biogenesis protein AIM24 SMALA_RS26065 c9081a48f38b8deace9028d3e588197d 227 Pfam PF01987 Mitochondrial biogenesis AIM24 19 215 1.3E-37 T 29-03-2018 IPR002838 Mitochondrial biogenesis protein AIM24 SMALA_RS26065 c9081a48f38b8deace9028d3e588197d 227 SUPERFAMILY SSF51219 18 217 5.49E-47 T 29-03-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain SMALA_RS02835 78d871589dcc9cdf2aa88bcc8d81c973 307 Gene3D G3DSA:1.10.10.10 1 85 4.1E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS02835 78d871589dcc9cdf2aa88bcc8d81c973 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 6.1E-19 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS02835 78d871589dcc9cdf2aa88bcc8d81c973 307 Gene3D G3DSA:3.40.190.10 179 267 1.8E-15 T 29-03-2018 SMALA_RS02835 78d871589dcc9cdf2aa88bcc8d81c973 307 Pfam PF03466 LysR substrate binding domain 101 293 2.6E-32 T 29-03-2018 IPR005119 LysR, substrate-binding SMALA_RS02835 78d871589dcc9cdf2aa88bcc8d81c973 307 Gene3D G3DSA:3.40.190.10 91 178 3.1E-16 T 29-03-2018 SMALA_RS02835 78d871589dcc9cdf2aa88bcc8d81c973 307 SUPERFAMILY SSF46785 2 84 1.73E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS02835 78d871589dcc9cdf2aa88bcc8d81c973 307 SUPERFAMILY SSF53850 93 294 3.5E-31 T 29-03-2018 SMALA_RS24940 b0582e68f5f35ddbaf7830eede6ada2a 343 Pfam PF03320 Bacterial fructose-1,6-bisphosphatase, glpX-encoded 19 326 4.6E-142 T 29-03-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 SMALA_RS24940 b0582e68f5f35ddbaf7830eede6ada2a 343 TIGRFAM TIGR00330 glpX: fructose-1,6-bisphosphatase, class II 19 330 7.3E-115 T 29-03-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 SMALA_RS24940 b0582e68f5f35ddbaf7830eede6ada2a 343 SUPERFAMILY SSF56655 17 328 3.48E-110 T 29-03-2018 SMALA_RS24940 b0582e68f5f35ddbaf7830eede6ada2a 343 PIRSF PIRSF004532 17 337 1.3E-144 T 29-03-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 SMALA_RS24940 b0582e68f5f35ddbaf7830eede6ada2a 343 Gene3D G3DSA:3.30.540.10 170 337 2.2E-56 T 29-03-2018 SMALA_RS24940 b0582e68f5f35ddbaf7830eede6ada2a 343 Gene3D G3DSA:3.30.540.10 16 169 1.3E-50 T 29-03-2018 SMALA_RS13360 dc8dc95a570f85ad6849e8459185a841 580 TIGRFAM TIGR03767 P_acnes_RR: metallophosphoesterase, PPA1498 family 85 580 2.3E-215 T 29-03-2018 IPR022506 Metallophosphoesterase, PPA1498 SMALA_RS13360 dc8dc95a570f85ad6849e8459185a841 580 Gene3D G3DSA:3.60.21.10 115 526 6.7E-36 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SMALA_RS13360 dc8dc95a570f85ad6849e8459185a841 580 SUPERFAMILY SSF56300 364 523 2.63E-38 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SMALA_RS13360 dc8dc95a570f85ad6849e8459185a841 580 SUPERFAMILY SSF56300 265 292 2.63E-38 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SMALA_RS13360 dc8dc95a570f85ad6849e8459185a841 580 SUPERFAMILY SSF56300 120 206 2.63E-38 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SMALA_RS13360 dc8dc95a570f85ad6849e8459185a841 580 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 17 44 7.5E-4 T 29-03-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal SMALA_RS13360 dc8dc95a570f85ad6849e8459185a841 580 Pfam PF00149 Calcineurin-like phosphoesterase 121 484 7.2E-8 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 SMALA_RS01980 4542b028c6ae3ded71fe149c67fbb2cb 365 SUPERFAMILY SSF47413 26 84 1.54E-18 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS01980 4542b028c6ae3ded71fe149c67fbb2cb 365 Pfam PF13377 Periplasmic binding protein-like domain 192 356 1.3E-39 T 29-03-2018 SMALA_RS01980 4542b028c6ae3ded71fe149c67fbb2cb 365 Gene3D G3DSA:3.40.50.2300 81 197 7.8E-27 T 29-03-2018 SMALA_RS01980 4542b028c6ae3ded71fe149c67fbb2cb 365 SMART SM00354 26 96 3.2E-31 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS01980 4542b028c6ae3ded71fe149c67fbb2cb 365 Pfam PF00356 Bacterial regulatory proteins, lacI family 28 73 1.3E-18 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS01980 4542b028c6ae3ded71fe149c67fbb2cb 365 Gene3D G3DSA:3.40.50.2300 198 345 2.1E-44 T 29-03-2018 SMALA_RS01980 4542b028c6ae3ded71fe149c67fbb2cb 365 SUPERFAMILY SSF53822 86 357 1.43E-66 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SMALA_RS01980 4542b028c6ae3ded71fe149c67fbb2cb 365 Gene3D G3DSA:1.10.260.40 27 80 8.4E-24 T 29-03-2018 SMALA_RS01980 4542b028c6ae3ded71fe149c67fbb2cb 365 ProSitePatterns PS00356 LacI-type HTH domain signature. 29 47 - T 29-03-2018 SMALA_RS40455 826ca2d3969bb5b73b56f378345fc1e5 365 Gene3D G3DSA:3.40.710.10 1 363 5.0E-72 T 29-03-2018 SMALA_RS40455 826ca2d3969bb5b73b56f378345fc1e5 365 Pfam PF00144 Beta-lactamase 12 353 4.1E-58 T 29-03-2018 IPR001466 Beta-lactamase-related SMALA_RS40455 826ca2d3969bb5b73b56f378345fc1e5 365 SUPERFAMILY SSF56601 5 352 1.49E-63 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMALA_RS41215 d88b59138b16f68994550020a313d17a 153 Gene3D G3DSA:2.60.120.10 5 146 5.1E-16 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SMALA_RS41215 d88b59138b16f68994550020a313d17a 153 Pfam PF00027 Cyclic nucleotide-binding domain 28 114 1.9E-8 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain SMALA_RS41215 d88b59138b16f68994550020a313d17a 153 SUPERFAMILY SSF51206 9 141 7.2E-20 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like SMALA_RS36525 273375430570eb336d0110c882fe5b81 771 Pfam PF00117 Glutamine amidotransferase class-I 5 186 1.0E-38 T 29-03-2018 IPR017926 Glutamine amidotransferase SMALA_RS36525 273375430570eb336d0110c882fe5b81 771 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 4 186 4.5E-43 T 29-03-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 SMALA_RS36525 273375430570eb336d0110c882fe5b81 771 Pfam PF00425 chorismate binding enzyme 478 732 5.0E-90 T 29-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal SMALA_RS36525 273375430570eb336d0110c882fe5b81 771 SUPERFAMILY SSF56322 269 740 1.83E-130 T 29-03-2018 IPR005801 ADC synthase GO:0009058 SMALA_RS36525 273375430570eb336d0110c882fe5b81 771 PRINTS PR00097 Anthranilate synthase component II signature 102 110 5.4E-27 T 29-03-2018 SMALA_RS36525 273375430570eb336d0110c882fe5b81 771 PRINTS PR00097 Anthranilate synthase component II signature 3 17 5.4E-27 T 29-03-2018 SMALA_RS36525 273375430570eb336d0110c882fe5b81 771 PRINTS PR00097 Anthranilate synthase component II signature 166 179 5.4E-27 T 29-03-2018 SMALA_RS36525 273375430570eb336d0110c882fe5b81 771 PRINTS PR00097 Anthranilate synthase component II signature 122 134 5.4E-27 T 29-03-2018 SMALA_RS36525 273375430570eb336d0110c882fe5b81 771 PRINTS PR00097 Anthranilate synthase component II signature 77 88 5.4E-27 T 29-03-2018 SMALA_RS36525 273375430570eb336d0110c882fe5b81 771 PRINTS PR00097 Anthranilate synthase component II signature 49 58 5.4E-27 T 29-03-2018 SMALA_RS36525 273375430570eb336d0110c882fe5b81 771 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 77 93 3.9E-6 T 29-03-2018 SMALA_RS36525 273375430570eb336d0110c882fe5b81 771 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 46 60 3.9E-6 T 29-03-2018 SMALA_RS36525 273375430570eb336d0110c882fe5b81 771 SUPERFAMILY SSF52317 2 188 1.46E-45 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS36525 273375430570eb336d0110c882fe5b81 771 Gene3D G3DSA:3.60.120.10 270 744 2.4E-155 T 29-03-2018 IPR005801 ADC synthase GO:0009058 SMALA_RS36525 273375430570eb336d0110c882fe5b81 771 Pfam PF04715 Anthranilate synthase component I, N terminal region 283 423 1.4E-21 T 29-03-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 SMALA_RS36525 273375430570eb336d0110c882fe5b81 771 PRINTS PR00096 Glutamine amidotransferase superfamily signature 166 179 2.1E-12 T 29-03-2018 SMALA_RS36525 273375430570eb336d0110c882fe5b81 771 PRINTS PR00096 Glutamine amidotransferase superfamily signature 49 58 2.1E-12 T 29-03-2018 SMALA_RS36525 273375430570eb336d0110c882fe5b81 771 PRINTS PR00096 Glutamine amidotransferase superfamily signature 77 88 2.1E-12 T 29-03-2018 SMALA_RS36525 273375430570eb336d0110c882fe5b81 771 Gene3D G3DSA:3.40.50.880 1 193 3.5E-49 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS36525 273375430570eb336d0110c882fe5b81 771 TIGRFAM TIGR00553 pabB: aminodeoxychorismate synthase, component I 379 734 2.2E-101 T 29-03-2018 IPR005802 Para-aminobenzoate synthase, component I GO:0009396 KEGG: 00790+2.6.1.85|MetaCyc: PWY-6543 SMALA_RS23825 b90f8db21e46a59a4fefdcbe8cf945ea 310 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 2.8E-17 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS23825 b90f8db21e46a59a4fefdcbe8cf945ea 310 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 2.8E-17 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS23825 b90f8db21e46a59a4fefdcbe8cf945ea 310 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 2.8E-17 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS23825 b90f8db21e46a59a4fefdcbe8cf945ea 310 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 2.8E-17 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS23825 b90f8db21e46a59a4fefdcbe8cf945ea 310 Pfam PF00106 short chain dehydrogenase 10 198 4.6E-47 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS23825 b90f8db21e46a59a4fefdcbe8cf945ea 310 SUPERFAMILY SSF51735 6 264 3.27E-59 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS23825 b90f8db21e46a59a4fefdcbe8cf945ea 310 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 4.2E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS23825 b90f8db21e46a59a4fefdcbe8cf945ea 310 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 4.2E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS23825 b90f8db21e46a59a4fefdcbe8cf945ea 310 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 4.2E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS23825 b90f8db21e46a59a4fefdcbe8cf945ea 310 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 10 189 0.0011 T 29-03-2018 SMALA_RS23825 b90f8db21e46a59a4fefdcbe8cf945ea 310 Gene3D G3DSA:3.40.50.720 1 271 3.5E-54 T 29-03-2018 SMALA_RS23825 b90f8db21e46a59a4fefdcbe8cf945ea 310 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMALA_RS40335 d369dc4ef05c1c9a3737e860a5616e0e 335 Gene3D G3DSA:3.10.129.10 195 335 1.9E-15 T 29-03-2018 SMALA_RS40335 d369dc4ef05c1c9a3737e860a5616e0e 335 Gene3D G3DSA:3.10.129.10 19 168 1.6E-12 T 29-03-2018 SMALA_RS40335 d369dc4ef05c1c9a3737e860a5616e0e 335 SUPERFAMILY SSF54637 200 326 5.11E-14 T 29-03-2018 IPR029069 HotDog domain SMALA_RS40335 d369dc4ef05c1c9a3737e860a5616e0e 335 SUPERFAMILY SSF54637 32 166 1.77E-9 T 29-03-2018 IPR029069 HotDog domain SMALA_RS00595 f9c80879e5d007e7ea86e0d63a5a4316 497 SUPERFAMILY SSF48150 322 489 4.36E-37 T 29-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 SMALA_RS00595 f9c80879e5d007e7ea86e0d63a5a4316 497 Pfam PF06029 AlkA N-terminal domain 212 332 2.6E-33 T 29-03-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal SMALA_RS00595 f9c80879e5d007e7ea86e0d63a5a4316 497 SMART SM00342 98 181 3.2E-15 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS00595 f9c80879e5d007e7ea86e0d63a5a4316 497 Gene3D G3DSA:1.10.10.60 136 192 1.3E-7 T 29-03-2018 SMALA_RS00595 f9c80879e5d007e7ea86e0d63a5a4316 497 Gene3D G3DSA:3.30.310.20 211 332 9.2E-40 T 29-03-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal SMALA_RS00595 f9c80879e5d007e7ea86e0d63a5a4316 497 Gene3D G3DSA:1.10.10.60 78 135 0.0018 T 29-03-2018 SMALA_RS00595 f9c80879e5d007e7ea86e0d63a5a4316 497 SUPERFAMILY SSF57884 2 80 4.71E-31 T 29-03-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 SMALA_RS00595 f9c80879e5d007e7ea86e0d63a5a4316 497 SMART SM01009 211 332 1.2E-46 T 29-03-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal SMALA_RS00595 f9c80879e5d007e7ea86e0d63a5a4316 497 Gene3D G3DSA:3.40.10.10 1 71 3.0E-25 T 29-03-2018 IPR035451 Ada-like domain SMALA_RS00595 f9c80879e5d007e7ea86e0d63a5a4316 497 Gene3D G3DSA:1.10.1670.10 435 461 7.9E-4 T 29-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 SMALA_RS00595 f9c80879e5d007e7ea86e0d63a5a4316 497 SUPERFAMILY SSF55945 212 312 7.22E-22 T 29-03-2018 SMALA_RS00595 f9c80879e5d007e7ea86e0d63a5a4316 497 Gene3D G3DSA:1.10.340.30 333 434 5.9E-23 T 29-03-2018 SMALA_RS00595 f9c80879e5d007e7ea86e0d63a5a4316 497 SMART SM00478 342 493 9.6E-8 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 SMALA_RS00595 f9c80879e5d007e7ea86e0d63a5a4316 497 Gene3D G3DSA:1.10.1670.10 462 494 3.5E-9 T 29-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 SMALA_RS00595 f9c80879e5d007e7ea86e0d63a5a4316 497 Pfam PF02805 Metal binding domain of Ada 6 69 2.5E-29 T 29-03-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 SMALA_RS00595 f9c80879e5d007e7ea86e0d63a5a4316 497 Pfam PF12833 Helix-turn-helix domain 104 182 2.2E-16 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS00595 f9c80879e5d007e7ea86e0d63a5a4316 497 SUPERFAMILY SSF46689 135 182 2.2E-7 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS21170 94fc59645a8dee812a6ce8a2e73dcfdf 512 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 32 132 7.8E-21 T 29-03-2018 SMALA_RS21170 94fc59645a8dee812a6ce8a2e73dcfdf 512 SUPERFAMILY SSF55874 25 137 3.01E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS21170 94fc59645a8dee812a6ce8a2e73dcfdf 512 Gene3D G3DSA:3.30.565.10 19 219 1.6E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS18425 def1d49f3805e781d35edc7cac813dc5 564 SUPERFAMILY SSF143975 4 364 1.31E-91 T 29-03-2018 SMALA_RS18425 def1d49f3805e781d35edc7cac813dc5 564 Pfam PF00920 Dehydratase family 35 556 2.8E-143 T 29-03-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 SMALA_RS18425 def1d49f3805e781d35edc7cac813dc5 564 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 123 133 - T 29-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 SMALA_RS18425 def1d49f3805e781d35edc7cac813dc5 564 SUPERFAMILY SSF52016 374 559 6.83E-39 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel SMALA_RS21425 f154e7d804e05e30976f7b4da4bf8ca6 347 Gene3D G3DSA:3.40.50.300 3 337 1.6E-65 T 29-03-2018 SMALA_RS21425 f154e7d804e05e30976f7b4da4bf8ca6 347 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS21425 f154e7d804e05e30976f7b4da4bf8ca6 347 SUPERFAMILY SSF52540 5 227 1.0E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS21425 f154e7d804e05e30976f7b4da4bf8ca6 347 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 14 308 7.5E-101 T 29-03-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 SMALA_RS21425 f154e7d804e05e30976f7b4da4bf8ca6 347 SMART SM00382 31 214 1.2E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS21425 f154e7d804e05e30976f7b4da4bf8ca6 347 Pfam PF00005 ABC transporter 22 165 8.2E-26 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS15350 5830562425d1c5d207811ff104ebe57f 195 Pfam PF02622 Uncharacterized ACR, COG1678 16 178 5.0E-36 T 29-03-2018 IPR003774 Protein of unknown function UPF0301 SMALA_RS15350 5830562425d1c5d207811ff104ebe57f 195 SUPERFAMILY SSF143456 4 189 2.09E-46 T 29-03-2018 SMALA_RS15350 5830562425d1c5d207811ff104ebe57f 195 Gene3D G3DSA:3.40.1740.10 121 184 6.2E-9 T 29-03-2018 SMALA_RS15350 5830562425d1c5d207811ff104ebe57f 195 Gene3D G3DSA:3.40.1740.10 1 83 1.1E-19 T 29-03-2018 SMALA_RS15350 5830562425d1c5d207811ff104ebe57f 195 Hamap MF_00758 UPF0301 protein YqgE [yqgE]. 5 192 26.552 T 29-03-2018 IPR003774 Protein of unknown function UPF0301 SMALA_RS33865 63ce1f514bba6a6c705e7b065c401ad6 327 Pfam PF15892 BNR repeat-containing family member 50 233 7.4E-43 T 29-03-2018 SMALA_RS33865 63ce1f514bba6a6c705e7b065c401ad6 327 Gene3D G3DSA:2.120.10.10 17 321 3.0E-8 T 29-03-2018 SMALA_RS22920 5d8f9478eca778b2e40bfdf5ee6459c6 539 Gene3D G3DSA:1.10.560.10 374 516 8.0E-24 T 29-03-2018 IPR027413 GroEL-like equatorial domain SMALA_RS22920 5d8f9478eca778b2e40bfdf5ee6459c6 539 ProSitePatterns PS00296 Chaperonins cpn60 signature. 405 416 - T 29-03-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 SMALA_RS22920 5d8f9478eca778b2e40bfdf5ee6459c6 539 Hamap MF_00600 60 kDa chaperonin [groL]. 1 537 41.184 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 SMALA_RS22920 5d8f9478eca778b2e40bfdf5ee6459c6 539 SUPERFAMILY SSF48592 6 133 2.5E-72 T 29-03-2018 SMALA_RS22920 5d8f9478eca778b2e40bfdf5ee6459c6 539 SUPERFAMILY SSF48592 406 521 2.5E-72 T 29-03-2018 SMALA_RS22920 5d8f9478eca778b2e40bfdf5ee6459c6 539 SUPERFAMILY SSF52029 184 376 4.04E-79 T 29-03-2018 IPR027409 GroEL-like apical domain SMALA_RS22920 5d8f9478eca778b2e40bfdf5ee6459c6 539 SUPERFAMILY SSF54849 136 203 2.22E-24 T 29-03-2018 SMALA_RS22920 5d8f9478eca778b2e40bfdf5ee6459c6 539 Gene3D G3DSA:1.10.560.10 1 188 2.7E-38 T 29-03-2018 IPR027413 GroEL-like equatorial domain SMALA_RS22920 5d8f9478eca778b2e40bfdf5ee6459c6 539 Gene3D G3DSA:3.50.7.10 189 373 2.1E-91 T 29-03-2018 IPR027409 GroEL-like apical domain SMALA_RS22920 5d8f9478eca778b2e40bfdf5ee6459c6 539 PRINTS PR00298 60kDa chaperonin signature 26 52 7.9E-71 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 SMALA_RS22920 5d8f9478eca778b2e40bfdf5ee6459c6 539 PRINTS PR00298 60kDa chaperonin signature 350 375 7.9E-71 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 SMALA_RS22920 5d8f9478eca778b2e40bfdf5ee6459c6 539 PRINTS PR00298 60kDa chaperonin signature 268 291 7.9E-71 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 SMALA_RS22920 5d8f9478eca778b2e40bfdf5ee6459c6 539 PRINTS PR00298 60kDa chaperonin signature 82 109 7.9E-71 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 SMALA_RS22920 5d8f9478eca778b2e40bfdf5ee6459c6 539 PRINTS PR00298 60kDa chaperonin signature 398 419 7.9E-71 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 SMALA_RS22920 5d8f9478eca778b2e40bfdf5ee6459c6 539 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 524 9.3E-93 T 29-03-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 SMALA_RS22920 5d8f9478eca778b2e40bfdf5ee6459c6 539 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 526 3.5E-242 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 SMALA_RS06260 dfc743207079b6cdba8e63f6c7e6f83b 514 SUPERFAMILY SSF51395 10 480 6.28E-112 T 29-03-2018 SMALA_RS06260 dfc743207079b6cdba8e63f6c7e6f83b 514 PIRSF PIRSF006429 4 503 1.6E-139 T 29-03-2018 IPR024188 Glutamate synthase large subunit-like protein SMALA_RS06260 dfc743207079b6cdba8e63f6c7e6f83b 514 Gene3D G3DSA:3.20.20.70 64 476 4.3E-76 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS06260 dfc743207079b6cdba8e63f6c7e6f83b 514 Pfam PF01645 Conserved region in glutamate synthase 138 454 3.7E-75 T 29-03-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 SMALA_RS41005 ac0da0e67ae8178760fccb82e7eb30d2 158 SUPERFAMILY SSF52242 12 145 1.57E-17 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 SMALA_RS41005 ac0da0e67ae8178760fccb82e7eb30d2 158 Pfam PF02310 B12 binding domain 16 105 5.0E-11 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 SMALA_RS41005 ac0da0e67ae8178760fccb82e7eb30d2 158 Gene3D G3DSA:3.40.50.280 4 150 1.3E-26 T 29-03-2018 SMALA_RS04880 479396ff8579d5f392dc1b037b035469 793 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 316 332 4.0E-14 T 29-03-2018 SMALA_RS04880 479396ff8579d5f392dc1b037b035469 793 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 129 144 4.0E-14 T 29-03-2018 SMALA_RS04880 479396ff8579d5f392dc1b037b035469 793 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 4.0E-14 T 29-03-2018 SMALA_RS04880 479396ff8579d5f392dc1b037b035469 793 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 268 283 4.0E-14 T 29-03-2018 SMALA_RS04880 479396ff8579d5f392dc1b037b035469 793 Pfam PF01494 FAD binding domain 130 328 5.7E-15 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 SMALA_RS04880 479396ff8579d5f392dc1b037b035469 793 SUPERFAMILY SSF51395 394 739 7.55E-113 T 29-03-2018 SMALA_RS04880 479396ff8579d5f392dc1b037b035469 793 Gene3D G3DSA:3.20.20.70 385 747 5.4E-115 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS04880 479396ff8579d5f392dc1b037b035469 793 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 396 732 1.2E-62 T 29-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 SMALA_RS04880 479396ff8579d5f392dc1b037b035469 793 Gene3D G3DSA:3.50.50.60 1 384 4.7E-40 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS04880 479396ff8579d5f392dc1b037b035469 793 SUPERFAMILY SSF51905 2 150 8.7E-45 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS04880 479396ff8579d5f392dc1b037b035469 793 SUPERFAMILY SSF51905 255 347 8.7E-45 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS14140 b7a424540f75076e9025ec2906da8b2c 209 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 35 149 5.8E-13 T 29-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 SMALA_RS14140 b7a424540f75076e9025ec2906da8b2c 209 SUPERFAMILY SSF55961 20 161 2.39E-31 T 29-03-2018 SMALA_RS14140 b7a424540f75076e9025ec2906da8b2c 209 Gene3D G3DSA:3.30.530.20 6 188 3.0E-35 T 29-03-2018 IPR023393 START-like domain SMALA_RS22950 a023e43ce6be78185e240ececfe7ead8 203 Pfam PF04542 Sigma-70 region 2 42 110 5.0E-9 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS22950 a023e43ce6be78185e240ececfe7ead8 203 SUPERFAMILY SSF88659 128 201 3.36E-14 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS22950 a023e43ce6be78185e240ececfe7ead8 203 Pfam PF04545 Sigma-70, region 4 150 199 6.4E-12 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS22950 a023e43ce6be78185e240ececfe7ead8 203 Gene3D G3DSA:1.10.1740.10 24 115 4.8E-16 T 29-03-2018 SMALA_RS22950 a023e43ce6be78185e240ececfe7ead8 203 SUPERFAMILY SSF88946 23 126 5.49E-14 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS22950 a023e43ce6be78185e240ececfe7ead8 203 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 36 198 3.0E-22 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS22950 a023e43ce6be78185e240ececfe7ead8 203 Gene3D G3DSA:1.10.10.10 123 203 2.5E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS02690 7a95be487d506092bf8932ba0e1eb2eb 124 Gene3D G3DSA:1.10.10.10 10 122 9.3E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS02690 7a95be487d506092bf8932ba0e1eb2eb 124 Pfam PF01638 HxlR-like helix-turn-helix 28 115 8.3E-22 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type SMALA_RS02690 7a95be487d506092bf8932ba0e1eb2eb 124 SUPERFAMILY SSF46785 14 115 3.24E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS13125 8d597dfb5bb6f775d907a9ef541b6238 85 SUPERFAMILY SSF110324 2 82 4.88E-31 T 29-03-2018 SMALA_RS13125 8d597dfb5bb6f775d907a9ef541b6238 85 ProSitePatterns PS00831 Ribosomal protein L27 signature. 34 48 - T 29-03-2018 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS13125 8d597dfb5bb6f775d907a9ef541b6238 85 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 28 71 4.0E-17 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS13125 8d597dfb5bb6f775d907a9ef541b6238 85 Gene3D G3DSA:2.40.50.100 20 83 1.1E-27 T 29-03-2018 SMALA_RS13125 8d597dfb5bb6f775d907a9ef541b6238 85 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 1 83 26.964 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS13125 8d597dfb5bb6f775d907a9ef541b6238 85 PRINTS PR00063 Ribosomal protein L27 signature 54 78 4.2E-35 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS13125 8d597dfb5bb6f775d907a9ef541b6238 85 PRINTS PR00063 Ribosomal protein L27 signature 29 53 4.2E-35 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS13125 8d597dfb5bb6f775d907a9ef541b6238 85 PRINTS PR00063 Ribosomal protein L27 signature 4 28 4.2E-35 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS13125 8d597dfb5bb6f775d907a9ef541b6238 85 Pfam PF01016 Ribosomal L27 protein 2 80 1.6E-35 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS13125 8d597dfb5bb6f775d907a9ef541b6238 85 TIGRFAM TIGR00062 L27: ribosomal protein bL27 1 81 9.9E-35 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS26410 0f54032423c717026738c15c178981ee 158 Gene3D G3DSA:3.30.750.24 45 158 3.6E-13 T 29-03-2018 IPR002645 STAS domain SMALA_RS26410 0f54032423c717026738c15c178981ee 158 Pfam PF13466 STAS domain 56 121 9.6E-10 T 29-03-2018 IPR002645 STAS domain SMALA_RS26410 0f54032423c717026738c15c178981ee 158 SUPERFAMILY SSF52091 47 150 1.92E-18 T 29-03-2018 IPR002645 STAS domain SMALA_RS26410 0f54032423c717026738c15c178981ee 158 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 45 147 1.5E-18 T 29-03-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 SMALA_RS19790 32d862aa26f88d5f08f5b884c8e895c0 385 Pfam PF00072 Response regulator receiver domain 248 361 3.9E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS19790 32d862aa26f88d5f08f5b884c8e895c0 385 Gene3D G3DSA:3.40.50.2300 241 380 1.7E-36 T 29-03-2018 SMALA_RS19790 32d862aa26f88d5f08f5b884c8e895c0 385 SMART SM00448 246 361 1.1E-31 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS19790 32d862aa26f88d5f08f5b884c8e895c0 385 SUPERFAMILY SSF52172 244 376 1.14E-35 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS37240 84fdd9e84549fba74bfe4f3fc3c80f04 419 PIRSF PIRSF000521 16 116 3.8E-7 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMALA_RS37240 84fdd9e84549fba74bfe4f3fc3c80f04 419 PIRSF PIRSF000521 109 414 1.5E-42 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMALA_RS37240 84fdd9e84549fba74bfe4f3fc3c80f04 419 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 229 266 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMALA_RS37240 84fdd9e84549fba74bfe4f3fc3c80f04 419 SUPERFAMILY SSF53383 10 412 1.17E-132 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS37240 84fdd9e84549fba74bfe4f3fc3c80f04 419 Gene3D G3DSA:3.90.1150.10 298 419 5.3E-31 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS37240 84fdd9e84549fba74bfe4f3fc3c80f04 419 Pfam PF00202 Aminotransferase class-III 11 411 2.6E-118 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMALA_RS37240 84fdd9e84549fba74bfe4f3fc3c80f04 419 Gene3D G3DSA:3.40.640.10 38 297 7.6E-86 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS16925 b02d7baf2bee6a64a136d1dc107e7b79 136 Gene3D G3DSA:3.40.50.280 2 136 3.0E-38 T 29-03-2018 SMALA_RS16925 b02d7baf2bee6a64a136d1dc107e7b79 136 SUPERFAMILY SSF52242 5 131 7.72E-50 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 SMALA_RS16925 b02d7baf2bee6a64a136d1dc107e7b79 136 Pfam PF02310 B12 binding domain 7 119 2.3E-24 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 SMALA_RS16925 b02d7baf2bee6a64a136d1dc107e7b79 136 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 7 132 1.3E-49 T 29-03-2018 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMALA_RS29095 f17dc2c58ad63ea51a46816e2b7d4ec9 817 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 42 478 3.3E-147 T 29-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMALA_RS29095 f17dc2c58ad63ea51a46816e2b7d4ec9 817 SUPERFAMILY SSF101904 513 778 4.05E-42 T 29-03-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal SMALA_RS29095 f17dc2c58ad63ea51a46816e2b7d4ec9 817 SUPERFAMILY SSF56719 41 498 1.31E-163 T 29-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 SMALA_RS29095 f17dc2c58ad63ea51a46816e2b7d4ec9 817 SMART SM00434 21 476 2.9E-253 T 29-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMALA_RS29095 f17dc2c58ad63ea51a46816e2b7d4ec9 817 Gene3D G3DSA:3.30.1360.40 247 344 6.6E-28 T 29-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 SMALA_RS29095 f17dc2c58ad63ea51a46816e2b7d4ec9 817 Gene3D G3DSA:3.90.199.10 44 224 3.8E-80 T 29-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 SMALA_RS29095 f17dc2c58ad63ea51a46816e2b7d4ec9 817 Gene3D G3DSA:2.120.10.90 511 780 1.0E-53 T 29-03-2018 SMALA_RS29095 f17dc2c58ad63ea51a46816e2b7d4ec9 817 Gene3D G3DSA:1.10.268.10 356 498 2.5E-45 T 29-03-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMALA_RS29095 f17dc2c58ad63ea51a46816e2b7d4ec9 817 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 740 771 0.014 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 SMALA_RS29095 f17dc2c58ad63ea51a46816e2b7d4ec9 817 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 669 714 4.4E-7 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 SMALA_RS06525 3939abf37fdd856741be39f59d2376d9 172 SUPERFAMILY SSF46785 2 169 3.71E-33 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS06525 3939abf37fdd856741be39f59d2376d9 172 Pfam PF10400 Virulence activator alpha C-term 89 169 2.2E-14 T 29-03-2018 IPR018309 Transcription regulator PadR, C-terminal SMALA_RS06525 3939abf37fdd856741be39f59d2376d9 172 Gene3D G3DSA:1.10.10.10 1 85 1.0E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS06525 3939abf37fdd856741be39f59d2376d9 172 Pfam PF03551 Transcriptional regulator PadR-like family 7 77 4.5E-11 T 29-03-2018 IPR005149 Transcription regulator PadR, N-terminal SMALA_RS05910 9171885dc4ca684b8089c33eaa1bdcff 492 Gene3D G3DSA:3.30.70.250 150 193 6.4E-12 T 29-03-2018 SMALA_RS05910 9171885dc4ca684b8089c33eaa1bdcff 492 SUPERFAMILY SSF55048 137 201 2.49E-8 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS05910 9171885dc4ca684b8089c33eaa1bdcff 492 Pfam PF00550 Phosphopantetheine attachment site 414 481 5.9E-6 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS05910 9171885dc4ca684b8089c33eaa1bdcff 492 Pfam PF00698 Acyl transferase domain 27 223 3.1E-23 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS05910 9171885dc4ca684b8089c33eaa1bdcff 492 SUPERFAMILY SSF47336 407 487 2.22E-9 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS05910 9171885dc4ca684b8089c33eaa1bdcff 492 SUPERFAMILY SSF52151 10 138 1.67E-32 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS05910 9171885dc4ca684b8089c33eaa1bdcff 492 SUPERFAMILY SSF52151 203 299 1.67E-32 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS05910 9171885dc4ca684b8089c33eaa1bdcff 492 ProSitePatterns PS00012 Phosphopantetheine attachment site. 439 454 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS05910 9171885dc4ca684b8089c33eaa1bdcff 492 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 25 307 1.1E-17 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS05910 9171885dc4ca684b8089c33eaa1bdcff 492 Gene3D G3DSA:3.40.366.10 8 149 4.4E-18 T 29-03-2018 SMALA_RS05910 9171885dc4ca684b8089c33eaa1bdcff 492 Gene3D G3DSA:1.10.1200.10 399 492 1.1E-10 T 29-03-2018 SMALA_RS05910 9171885dc4ca684b8089c33eaa1bdcff 492 Gene3D G3DSA:3.40.366.10 194 317 2.9E-15 T 29-03-2018 SMALA_RS12665 1b6e1dda0d137f92c5a8b02be438a85a 497 Pfam PF07690 Major Facilitator Superfamily 17 408 8.1E-61 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS12665 1b6e1dda0d137f92c5a8b02be438a85a 497 PRINTS PR01036 Tetracycline resistance protein TetB signature 15 39 4.1E-7 T 29-03-2018 SMALA_RS12665 1b6e1dda0d137f92c5a8b02be438a85a 497 PRINTS PR01036 Tetracycline resistance protein TetB signature 399 418 4.1E-7 T 29-03-2018 SMALA_RS12665 1b6e1dda0d137f92c5a8b02be438a85a 497 PRINTS PR01036 Tetracycline resistance protein TetB signature 137 161 4.1E-7 T 29-03-2018 SMALA_RS12665 1b6e1dda0d137f92c5a8b02be438a85a 497 Gene3D G3DSA:1.20.1250.20 256 482 2.2E-24 T 29-03-2018 SMALA_RS12665 1b6e1dda0d137f92c5a8b02be438a85a 497 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 11 418 1.0E-88 T 29-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 SMALA_RS12665 1b6e1dda0d137f92c5a8b02be438a85a 497 Gene3D G3DSA:1.20.1250.20 200 255 0.16 T 29-03-2018 SMALA_RS12665 1b6e1dda0d137f92c5a8b02be438a85a 497 Gene3D G3DSA:1.20.1250.20 1 199 5.4E-38 T 29-03-2018 SMALA_RS12665 1b6e1dda0d137f92c5a8b02be438a85a 497 SUPERFAMILY SSF103473 248 472 1.74E-68 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS12665 1b6e1dda0d137f92c5a8b02be438a85a 497 SUPERFAMILY SSF103473 7 202 1.74E-68 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS19195 78b76ec5c68512d776541286ae32f5cd 388 PIRSF PIRSF000429 11 339 1.2E-20 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 SMALA_RS19195 78b76ec5c68512d776541286ae32f5cd 388 SUPERFAMILY SSF53901 266 373 6.62E-14 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS19195 78b76ec5c68512d776541286ae32f5cd 388 SUPERFAMILY SSF53901 13 237 1.86E-21 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS19195 78b76ec5c68512d776541286ae32f5cd 388 Gene3D G3DSA:3.40.47.10 1 139 3.5E-7 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS19195 78b76ec5c68512d776541286ae32f5cd 388 Gene3D G3DSA:3.40.47.10 152 381 1.6E-21 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS05410 ad994eda9ff667746ea2725ba07ab6b3 546 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 304 438 1.5E-24 T 29-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 SMALA_RS05410 ad994eda9ff667746ea2725ba07ab6b3 546 SUPERFAMILY SSF53067 3 250 8.91E-53 T 29-03-2018 SMALA_RS05410 ad994eda9ff667746ea2725ba07ab6b3 546 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 3 245 2.6E-49 T 29-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 SMALA_RS05410 ad994eda9ff667746ea2725ba07ab6b3 546 SUPERFAMILY SSF53067 249 486 9.33E-47 T 29-03-2018 SMALA_RS05410 ad994eda9ff667746ea2725ba07ab6b3 546 Gene3D G3DSA:3.30.420.40 2 238 1.7E-53 T 29-03-2018 SMALA_RS05410 ad994eda9ff667746ea2725ba07ab6b3 546 PIRSF PIRSF000538 1 490 4.7E-94 T 29-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 SMALA_RS05410 ad994eda9ff667746ea2725ba07ab6b3 546 Gene3D G3DSA:3.30.420.40 239 491 6.2E-49 T 29-03-2018 SMALA_RS05410 ad994eda9ff667746ea2725ba07ab6b3 546 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 356 376 - T 29-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 SMALA_RS08095 0769cfda0e6a908fef0bfe694eac4444 178 Gene3D G3DSA:3.90.79.10 2 178 1.0E-24 T 29-03-2018 SMALA_RS08095 0769cfda0e6a908fef0bfe694eac4444 178 PIRSF PIRSF017340 2 174 1.3E-69 T 29-03-2018 IPR024195 NUDIX hydrolase, YfcD, predicted GO:0016817 SMALA_RS08095 0769cfda0e6a908fef0bfe694eac4444 178 ProSitePatterns PS00893 Nudix box signature. 74 95 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 SMALA_RS08095 0769cfda0e6a908fef0bfe694eac4444 178 SUPERFAMILY SSF55811 11 172 2.17E-28 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMALA_RS08095 0769cfda0e6a908fef0bfe694eac4444 178 Pfam PF00293 NUDIX domain 37 151 8.4E-11 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SMALA_RS04350 90bf7a5c0a0a5fd6c41bcd26addc251f 3869 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2653 2950 7.7E-114 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS04350 90bf7a5c0a0a5fd6c41bcd26addc251f 3869 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 581 891 2.0E-126 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS04350 90bf7a5c0a0a5fd6c41bcd26addc251f 3869 Gene3D G3DSA:3.40.366.10 2646 2786 6.2E-43 T 29-03-2018 SMALA_RS04350 90bf7a5c0a0a5fd6c41bcd26addc251f 3869 Gene3D G3DSA:3.40.366.10 574 725 3.4E-47 T 29-03-2018 SMALA_RS04350 90bf7a5c0a0a5fd6c41bcd26addc251f 3869 SUPERFAMILY SSF51735 1727 1977 1.41E-43 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS04350 90bf7a5c0a0a5fd6c41bcd26addc251f 3869 Pfam PF00698 Acyl transferase domain 581 905 2.9E-57 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS04350 90bf7a5c0a0a5fd6c41bcd26addc251f 3869 Pfam PF00698 Acyl transferase domain 2652 2967 5.1E-83 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS04350 90bf7a5c0a0a5fd6c41bcd26addc251f 3869 SMART SM00825 Beta-ketoacyl synthase 37 463 1.1E-219 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS04350 90bf7a5c0a0a5fd6c41bcd26addc251f 3869 SMART SM00825 Beta-ketoacyl synthase 2112 2538 1.4E-220 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS04350 90bf7a5c0a0a5fd6c41bcd26addc251f 3869 Gene3D G3DSA:3.10.129.10 3017 3141 3.4E-9 T 29-03-2018 SMALA_RS04350 90bf7a5c0a0a5fd6c41bcd26addc251f 3869 Gene3D G3DSA:3.10.129.10 960 1078 1.3E-7 T 29-03-2018 SMALA_RS04350 90bf7a5c0a0a5fd6c41bcd26addc251f 3869 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2110 2360 3.4E-88 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS04350 90bf7a5c0a0a5fd6c41bcd26addc251f 3869 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 35 285 2.2E-88 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS04350 90bf7a5c0a0a5fd6c41bcd26addc251f 3869 SMART SM01294 2015 2082 1.4E-5 T 29-03-2018 SMALA_RS04350 90bf7a5c0a0a5fd6c41bcd26addc251f 3869 SMART SM01294 3774 3841 3.9E-4 T 29-03-2018 SMALA_RS04350 90bf7a5c0a0a5fd6c41bcd26addc251f 3869 Gene3D G3DSA:3.40.50.720 1724 1972 7.9E-45 T 29-03-2018 SMALA_RS04350 90bf7a5c0a0a5fd6c41bcd26addc251f 3869 Gene3D G3DSA:3.40.50.720 3480 3739 1.2E-49 T 29-03-2018 SMALA_RS04350 90bf7a5c0a0a5fd6c41bcd26addc251f 3869 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 2273 2289 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS04350 90bf7a5c0a0a5fd6c41bcd26addc251f 3869 SUPERFAMILY SSF52151 2841 2939 3.14E-68 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS04350 90bf7a5c0a0a5fd6c41bcd26addc251f 3869 SUPERFAMILY SSF52151 2649 2778 3.14E-68 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS04350 90bf7a5c0a0a5fd6c41bcd26addc251f 3869 Gene3D G3DSA:3.40.47.10 2109 2372 1.0E-81 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS04350 90bf7a5c0a0a5fd6c41bcd26addc251f 3869 Gene3D G3DSA:3.40.47.10 28 297 1.8E-81 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS04350 90bf7a5c0a0a5fd6c41bcd26addc251f 3869 SUPERFAMILY SSF51735 3300 3472 5.12E-26 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS04350 90bf7a5c0a0a5fd6c41bcd26addc251f 3869 Gene3D G3DSA:3.40.366.10 767 884 2.2E-31 T 29-03-2018 SMALA_RS04350 90bf7a5c0a0a5fd6c41bcd26addc251f 3869 Gene3D G3DSA:3.90.180.10 1406 1723 8.6E-61 T 29-03-2018 SMALA_RS04350 90bf7a5c0a0a5fd6c41bcd26addc251f 3869 SMART SM00826 958 1118 3.3E-75 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS04350 90bf7a5c0a0a5fd6c41bcd26addc251f 3869 SMART SM00826 3016 3178 3.2E-78 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS04350 90bf7a5c0a0a5fd6c41bcd26addc251f 3869 Pfam PF00550 Phosphopantetheine attachment site 3775 3841 3.8E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS04350 90bf7a5c0a0a5fd6c41bcd26addc251f 3869 Pfam PF00550 Phosphopantetheine attachment site 2019 2082 2.7E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS04350 90bf7a5c0a0a5fd6c41bcd26addc251f 3869 SUPERFAMILY SSF53901 32 408 1.14E-100 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS04350 90bf7a5c0a0a5fd6c41bcd26addc251f 3869 SUPERFAMILY SSF51735 1520 1692 1.64E-31 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS04350 90bf7a5c0a0a5fd6c41bcd26addc251f 3869 SUPERFAMILY SSF55048 2777 2840 1.57E-10 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS04350 90bf7a5c0a0a5fd6c41bcd26addc251f 3869 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2041 2056 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS04350 90bf7a5c0a0a5fd6c41bcd26addc251f 3869 SMART SM00829 1421 1721 1.7E-170 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS04350 90bf7a5c0a0a5fd6c41bcd26addc251f 3869 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3486 3666 1.0E-57 T 29-03-2018 SMALA_RS04350 90bf7a5c0a0a5fd6c41bcd26addc251f 3869 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1731 1911 7.8E-58 T 29-03-2018 SMALA_RS04350 90bf7a5c0a0a5fd6c41bcd26addc251f 3869 Gene3D G3DSA:1.10.1200.10 3765 3869 4.8E-22 T 29-03-2018 SMALA_RS04350 90bf7a5c0a0a5fd6c41bcd26addc251f 3869 Gene3D G3DSA:1.10.1200.10 2007 2108 1.8E-21 T 29-03-2018 SMALA_RS04350 90bf7a5c0a0a5fd6c41bcd26addc251f 3869 SUPERFAMILY SSF50129 1419 1557 1.02E-28 T 29-03-2018 IPR011032 GroES-like SMALA_RS04350 90bf7a5c0a0a5fd6c41bcd26addc251f 3869 Gene3D G3DSA:3.30.70.250 726 766 4.8E-19 T 29-03-2018 SMALA_RS04350 90bf7a5c0a0a5fd6c41bcd26addc251f 3869 Gene3D G3DSA:3.30.70.250 2787 2835 1.1E-14 T 29-03-2018 SMALA_RS04350 90bf7a5c0a0a5fd6c41bcd26addc251f 3869 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3800 3815 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS04350 90bf7a5c0a0a5fd6c41bcd26addc251f 3869 SUPERFAMILY SSF53901 2108 2482 6.61E-100 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS04350 90bf7a5c0a0a5fd6c41bcd26addc251f 3869 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 1441 1496 5.6E-7 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS04350 90bf7a5c0a0a5fd6c41bcd26addc251f 3869 Pfam PF14765 Polyketide synthase dehydratase 3016 3290 2.3E-57 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS04350 90bf7a5c0a0a5fd6c41bcd26addc251f 3869 Pfam PF14765 Polyketide synthase dehydratase 958 1231 1.4E-60 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS04350 90bf7a5c0a0a5fd6c41bcd26addc251f 3869 SMART SM00823 Phosphopantetheine attachment site 3773 3845 2.4E-31 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS04350 90bf7a5c0a0a5fd6c41bcd26addc251f 3869 SMART SM00823 Phosphopantetheine attachment site 2014 2086 1.1E-30 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS04350 90bf7a5c0a0a5fd6c41bcd26addc251f 3869 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 293 410 2.6E-43 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS04350 90bf7a5c0a0a5fd6c41bcd26addc251f 3869 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2368 2485 2.2E-44 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS04350 90bf7a5c0a0a5fd6c41bcd26addc251f 3869 SUPERFAMILY SSF47336 2009 2124 7.98E-23 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS04350 90bf7a5c0a0a5fd6c41bcd26addc251f 3869 Pfam PF08659 KR domain 1731 1910 1.5E-57 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS04350 90bf7a5c0a0a5fd6c41bcd26addc251f 3869 Pfam PF08659 KR domain 3486 3664 2.1E-56 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS04350 90bf7a5c0a0a5fd6c41bcd26addc251f 3869 SUPERFAMILY SSF52151 577 713 4.45E-72 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS04350 90bf7a5c0a0a5fd6c41bcd26addc251f 3869 SUPERFAMILY SSF52151 777 874 4.45E-72 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS04350 90bf7a5c0a0a5fd6c41bcd26addc251f 3869 SUPERFAMILY SSF55048 712 776 4.84E-12 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS04350 90bf7a5c0a0a5fd6c41bcd26addc251f 3869 Gene3D G3DSA:3.40.47.10 2375 2536 4.7E-63 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS04350 90bf7a5c0a0a5fd6c41bcd26addc251f 3869 Gene3D G3DSA:3.40.47.10 300 461 1.5E-60 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS04350 90bf7a5c0a0a5fd6c41bcd26addc251f 3869 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 413 544 7.4E-13 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS04350 90bf7a5c0a0a5fd6c41bcd26addc251f 3869 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2488 2612 2.0E-14 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS04350 90bf7a5c0a0a5fd6c41bcd26addc251f 3869 Gene3D G3DSA:3.40.366.10 2836 2955 5.7E-28 T 29-03-2018 SMALA_RS04350 90bf7a5c0a0a5fd6c41bcd26addc251f 3869 Pfam PF13602 Zinc-binding dehydrogenase 1612 1721 9.5E-16 T 29-03-2018 SMALA_RS04350 90bf7a5c0a0a5fd6c41bcd26addc251f 3869 SUPERFAMILY SSF51735 1235 1402 2.24E-27 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS04350 90bf7a5c0a0a5fd6c41bcd26addc251f 3869 SUPERFAMILY SSF47336 3765 3848 6.54E-22 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS04350 90bf7a5c0a0a5fd6c41bcd26addc251f 3869 SUPERFAMILY SSF51735 3484 3703 8.01E-44 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS03315 332d4a13f99f2ecff1ca5702669f1472 971 Gene3D G3DSA:3.90.1150.10 786 918 5.6E-44 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS03315 332d4a13f99f2ecff1ca5702669f1472 971 TIGRFAM TIGR00461 gcvP: glycine dehydrogenase 20 963 0.0 T 29-03-2018 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 SMALA_RS03315 332d4a13f99f2ecff1ca5702669f1472 971 Pfam PF02347 Glycine cleavage system P-protein 19 448 2.7E-176 T 29-03-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 SMALA_RS03315 332d4a13f99f2ecff1ca5702669f1472 971 Pfam PF02347 Glycine cleavage system P-protein 462 746 5.3E-13 T 29-03-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 SMALA_RS03315 332d4a13f99f2ecff1ca5702669f1472 971 SUPERFAMILY SSF53383 487 900 4.66E-101 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS03315 332d4a13f99f2ecff1ca5702669f1472 971 SUPERFAMILY SSF53383 942 965 4.66E-101 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS03315 332d4a13f99f2ecff1ca5702669f1472 971 Gene3D G3DSA:3.40.640.10 100 349 5.1E-37 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS03315 332d4a13f99f2ecff1ca5702669f1472 971 Gene3D G3DSA:3.40.640.10 543 785 2.2E-39 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS03315 332d4a13f99f2ecff1ca5702669f1472 971 Gene3D G3DSA:3.90.1150.10 350 450 9.4E-27 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS03315 332d4a13f99f2ecff1ca5702669f1472 971 SUPERFAMILY SSF53383 20 447 8.31E-100 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS03315 332d4a13f99f2ecff1ca5702669f1472 971 Hamap MF_00711 Glycine dehydrogenase (decarboxylating) [gcvP]. 11 969 25.72 T 29-03-2018 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 SMALA_RS28915 2ec60ee04025f83281fce2732c61b9b4 310 SUPERFAMILY SSF54506 161 300 1.3E-35 T 29-03-2018 SMALA_RS28915 2ec60ee04025f83281fce2732c61b9b4 310 Gene3D G3DSA:3.10.310.10 154 289 2.6E-37 T 29-03-2018 SMALA_RS28915 2ec60ee04025f83281fce2732c61b9b4 310 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 78 92 - T 29-03-2018 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 SMALA_RS28915 2ec60ee04025f83281fce2732c61b9b4 310 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 8 300 3.7E-65 T 29-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 SMALA_RS28915 2ec60ee04025f83281fce2732c61b9b4 310 SUPERFAMILY SSF54506 7 126 1.29E-31 T 29-03-2018 SMALA_RS28915 2ec60ee04025f83281fce2732c61b9b4 310 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 7 302 31.289 T 29-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 SMALA_RS28915 2ec60ee04025f83281fce2732c61b9b4 310 Gene3D G3DSA:3.10.310.10 1 153 5.2E-47 T 29-03-2018 SMALA_RS28915 2ec60ee04025f83281fce2732c61b9b4 310 Pfam PF01678 Diaminopimelate epimerase 9 127 1.7E-32 T 29-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 SMALA_RS28915 2ec60ee04025f83281fce2732c61b9b4 310 Pfam PF01678 Diaminopimelate epimerase 174 295 9.4E-29 T 29-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 SMALA_RS04380 648c8b02d3580906534a80c1380b3d92 370 Gene3D G3DSA:2.40.110.10 112 203 4.2E-30 T 29-03-2018 SMALA_RS04380 648c8b02d3580906534a80c1380b3d92 370 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 221 364 7.4E-30 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMALA_RS04380 648c8b02d3580906534a80c1380b3d92 370 Gene3D G3DSA:1.20.140.10 204 369 4.0E-33 T 29-03-2018 SMALA_RS04380 648c8b02d3580906534a80c1380b3d92 370 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 112 202 5.6E-19 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 SMALA_RS04380 648c8b02d3580906534a80c1380b3d92 370 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 16 109 1.3E-10 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS04380 648c8b02d3580906534a80c1380b3d92 370 SUPERFAMILY SSF56645 10 214 1.44E-50 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMALA_RS04380 648c8b02d3580906534a80c1380b3d92 370 Gene3D G3DSA:1.10.540.10 2 111 4.9E-17 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS04380 648c8b02d3580906534a80c1380b3d92 370 SUPERFAMILY SSF47203 222 366 3.22E-33 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMALA_RS20905 710eb0c6997f885146c79caa72331e87 226 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 4 204 1.1E-33 T 29-03-2018 SMALA_RS20905 710eb0c6997f885146c79caa72331e87 226 Gene3D G3DSA:3.40.50.880 1 225 1.2E-36 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS20905 710eb0c6997f885146c79caa72331e87 226 Hamap MF_00421 Phosphoribosylformylglycinamidine synthase subunit PurQ [purQ]. 3 221 40.237 T 29-03-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 SMALA_RS20905 710eb0c6997f885146c79caa72331e87 226 PIRSF PIRSF001586 1 226 2.3E-83 T 29-03-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 SMALA_RS20905 710eb0c6997f885146c79caa72331e87 226 SUPERFAMILY SSF52317 3 221 1.21E-67 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS20905 710eb0c6997f885146c79caa72331e87 226 SMART SM01211 2 223 3.2E-119 T 29-03-2018 SMALA_RS20905 710eb0c6997f885146c79caa72331e87 226 TIGRFAM TIGR01737 FGAM_synth_I: phosphoribosylformylglycinamidine synthase I 4 221 1.6E-82 T 29-03-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 SMALA_RS15190 d19e3fd815f64b343d8e7c25ac742e75 301 SUPERFAMILY SSF53850 91 298 1.76E-35 T 29-03-2018 SMALA_RS15190 d19e3fd815f64b343d8e7c25ac742e75 301 Gene3D G3DSA:3.40.190.10 182 270 2.8E-21 T 29-03-2018 SMALA_RS15190 d19e3fd815f64b343d8e7c25ac742e75 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 3.3E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS15190 d19e3fd815f64b343d8e7c25ac742e75 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 3.3E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS15190 d19e3fd815f64b343d8e7c25ac742e75 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 3.3E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS15190 d19e3fd815f64b343d8e7c25ac742e75 301 SUPERFAMILY SSF46785 2 112 4.67E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS15190 d19e3fd815f64b343d8e7c25ac742e75 301 Gene3D G3DSA:1.10.10.10 2 84 1.1E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS15190 d19e3fd815f64b343d8e7c25ac742e75 301 Gene3D G3DSA:3.40.190.10 90 181 1.1E-25 T 29-03-2018 SMALA_RS15190 d19e3fd815f64b343d8e7c25ac742e75 301 Pfam PF03466 LysR substrate binding domain 90 295 1.4E-39 T 29-03-2018 IPR005119 LysR, substrate-binding SMALA_RS15190 d19e3fd815f64b343d8e7c25ac742e75 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 1.6E-22 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS31005 8249c7cc19237b68a810f4f91c679131 191 SUPERFAMILY SSF109854 4 138 1.5E-22 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes SMALA_RS31005 8249c7cc19237b68a810f4f91c679131 191 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 10 186 4.1E-27 T 29-03-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type SMALA_RS31005 8249c7cc19237b68a810f4f91c679131 191 TIGRFAM TIGR03086 TIGR03086: TIGR03086 family protein 10 189 4.6E-54 T 29-03-2018 IPR017520 Conserved hypothetical protein CHP03086 SMALA_RS31005 8249c7cc19237b68a810f4f91c679131 191 Gene3D G3DSA:1.20.120.450 2 139 6.7E-22 T 29-03-2018 SMALA_RS31005 8249c7cc19237b68a810f4f91c679131 191 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 11 132 1.8E-13 T 29-03-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 SMALA_RS34770 d4f9c76c6cf2614d42d35033f3e13a0b 157 Pfam PF00877 NlpC/P60 family 56 142 4.9E-24 T 29-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain SMALA_RS34770 d4f9c76c6cf2614d42d35033f3e13a0b 157 Gene3D G3DSA:3.90.1720.10 36 157 6.2E-31 T 29-03-2018 SMALA_RS34770 d4f9c76c6cf2614d42d35033f3e13a0b 157 SUPERFAMILY SSF54001 41 152 2.55E-35 T 29-03-2018 SMALA_RS02720 cc000f6847cf76047f6b59393156c495 183 SUPERFAMILY SSF48498 77 180 9.79E-16 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS02720 cc000f6847cf76047f6b59393156c495 183 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 10 23 3.8E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS02720 cc000f6847cf76047f6b59393156c495 183 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 31 54 3.8E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS02720 cc000f6847cf76047f6b59393156c495 183 Gene3D G3DSA:1.10.357.10 54 181 9.7E-27 T 29-03-2018 SMALA_RS02720 cc000f6847cf76047f6b59393156c495 183 Pfam PF00440 Bacterial regulatory proteins, tetR family 10 55 5.0E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS02720 cc000f6847cf76047f6b59393156c495 183 SUPERFAMILY SSF46689 7 80 2.98E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS02720 cc000f6847cf76047f6b59393156c495 183 Gene3D G3DSA:1.10.10.60 2 53 4.6E-12 T 29-03-2018 SMALA_RS28960 d57cda75357836ebbf614730e02ba219 267 Pfam PF00717 Peptidase S24-like 186 250 1.4E-16 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C SMALA_RS28960 d57cda75357836ebbf614730e02ba219 267 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 222 234 2.6E-11 T 29-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 SMALA_RS28960 d57cda75357836ebbf614730e02ba219 267 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 183 193 2.6E-11 T 29-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 SMALA_RS28960 d57cda75357836ebbf614730e02ba219 267 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 194 205 2.6E-11 T 29-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 SMALA_RS28960 d57cda75357836ebbf614730e02ba219 267 Gene3D G3DSA:2.10.109.10 152 267 9.7E-28 T 29-03-2018 SMALA_RS28960 d57cda75357836ebbf614730e02ba219 267 SUPERFAMILY SSF46785 61 127 3.21E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS28960 d57cda75357836ebbf614730e02ba219 267 Pfam PF01726 LexA DNA binding domain 60 123 1.1E-29 T 29-03-2018 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 SMALA_RS28960 d57cda75357836ebbf614730e02ba219 267 Gene3D G3DSA:1.10.10.10 61 126 2.1E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS28960 d57cda75357836ebbf614730e02ba219 267 Hamap MF_00015 LexA repressor [lexA]. 61 267 34.262 T 29-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 SMALA_RS28960 d57cda75357836ebbf614730e02ba219 267 SUPERFAMILY SSF51306 147 265 2.27E-36 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C SMALA_RS28960 d57cda75357836ebbf614730e02ba219 267 TIGRFAM TIGR00498 lexA: repressor LexA 60 267 2.3E-75 T 29-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 SMALA_RS17700 48b65fedf4664e221440eab45d3b2a8d 433 SUPERFAMILY SSF47384 139 222 1.67E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS17700 48b65fedf4664e221440eab45d3b2a8d 433 Pfam PF00512 His Kinase A (phospho-acceptor) domain 157 220 9.8E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS17700 48b65fedf4664e221440eab45d3b2a8d 433 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 269 381 4.1E-23 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS17700 48b65fedf4664e221440eab45d3b2a8d 433 Gene3D G3DSA:3.30.450.20 52 160 0.0015 T 29-03-2018 SMALA_RS17700 48b65fedf4664e221440eab45d3b2a8d 433 SMART SM00387 267 383 2.8E-37 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS17700 48b65fedf4664e221440eab45d3b2a8d 433 Gene3D G3DSA:3.30.565.10 226 392 2.2E-42 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS17700 48b65fedf4664e221440eab45d3b2a8d 433 SUPERFAMILY SSF55874 212 380 7.6E-45 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS17700 48b65fedf4664e221440eab45d3b2a8d 433 SMART SM00388 156 222 5.0E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS17700 48b65fedf4664e221440eab45d3b2a8d 433 Gene3D G3DSA:1.10.287.130 161 218 3.3E-13 T 29-03-2018 SMALA_RS17700 48b65fedf4664e221440eab45d3b2a8d 433 PRINTS PR00344 Bacterial sensor protein C-terminal signature 343 361 2.0E-20 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS17700 48b65fedf4664e221440eab45d3b2a8d 433 PRINTS PR00344 Bacterial sensor protein C-terminal signature 308 322 2.0E-20 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS17700 48b65fedf4664e221440eab45d3b2a8d 433 PRINTS PR00344 Bacterial sensor protein C-terminal signature 326 336 2.0E-20 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS17700 48b65fedf4664e221440eab45d3b2a8d 433 PRINTS PR00344 Bacterial sensor protein C-terminal signature 367 380 2.0E-20 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS11185 2fe5f877f6cbe0f597ea7ff91d399f60 257 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 149 177 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMALA_RS11185 2fe5f877f6cbe0f597ea7ff91d399f60 257 Gene3D G3DSA:3.40.50.720 10 254 1.9E-56 T 29-03-2018 SMALA_RS11185 2fe5f877f6cbe0f597ea7ff91d399f60 257 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 11 193 0.0089 T 29-03-2018 SMALA_RS11185 2fe5f877f6cbe0f597ea7ff91d399f60 257 Pfam PF00106 short chain dehydrogenase 11 202 1.6E-49 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS11185 2fe5f877f6cbe0f597ea7ff91d399f60 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 136 152 6.2E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS11185 2fe5f877f6cbe0f597ea7ff91d399f60 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 6.2E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS11185 2fe5f877f6cbe0f597ea7ff91d399f60 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 181 6.2E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS11185 2fe5f877f6cbe0f597ea7ff91d399f60 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 6.2E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS11185 2fe5f877f6cbe0f597ea7ff91d399f60 257 SUPERFAMILY SSF51735 10 243 2.45E-61 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS11185 2fe5f877f6cbe0f597ea7ff91d399f60 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 142 150 1.6E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS11185 2fe5f877f6cbe0f597ea7ff91d399f60 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 1.6E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS11185 2fe5f877f6cbe0f597ea7ff91d399f60 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 162 181 1.6E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS36425 e1caec8718d94bb8cbf0cda8c2420e6f 183 Pfam PF06684 Amino acid synthesis 3 176 8.1E-64 T 29-03-2018 IPR009569 Amino acid synthesis, putative SMALA_RS36425 e1caec8718d94bb8cbf0cda8c2420e6f 183 Gene3D G3DSA:3.30.1330.110 1 183 1.5E-68 T 29-03-2018 IPR009569 Amino acid synthesis, putative SMALA_RS36425 e1caec8718d94bb8cbf0cda8c2420e6f 183 SUPERFAMILY SSF160519 1 181 1.14E-60 T 29-03-2018 IPR009569 Amino acid synthesis, putative SMALA_RS31615 f27d39683b3a93120131b07857cbcf32 781 Gene3D G3DSA:2.70.98.40 3 274 1.1E-75 T 29-03-2018 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 SMALA_RS31615 f27d39683b3a93120131b07857cbcf32 781 Pfam PF03632 Glycosyl hydrolase family 65 central catalytic domain 327 694 1.5E-137 T 29-03-2018 IPR005195 Glycoside hydrolase, family 65, central catalytic GO:0003824|GO:0005975 SMALA_RS31615 f27d39683b3a93120131b07857cbcf32 781 SUPERFAMILY SSF74650 6 271 5.02E-65 T 29-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 SMALA_RS31615 f27d39683b3a93120131b07857cbcf32 781 Pfam PF03633 Glycosyl hydrolase family 65, C-terminal domain 700 750 2.0E-17 T 29-03-2018 IPR005194 Glycoside hydrolase family 65, C-terminal SMALA_RS31615 f27d39683b3a93120131b07857cbcf32 781 Gene3D G3DSA:1.50.10.10 321 681 3.0E-111 T 29-03-2018 SMALA_RS31615 f27d39683b3a93120131b07857cbcf32 781 PIRSF PIRSF036289 1 762 4.6E-219 T 29-03-2018 IPR017045 Maltose phosphorylase/glycosyl hydrolase/vacuolar acid trehalase SMALA_RS31615 f27d39683b3a93120131b07857cbcf32 781 SUPERFAMILY SSF48208 279 748 6.32E-124 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 SMALA_RS31615 f27d39683b3a93120131b07857cbcf32 781 Pfam PF03636 Glycosyl hydrolase family 65, N-terminal domain 16 270 2.7E-60 T 29-03-2018 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 SMALA_RS31615 f27d39683b3a93120131b07857cbcf32 781 Gene3D G3DSA:2.60.420.10 682 753 6.5E-24 T 29-03-2018 SMALA_RS03765 b548b09ba7697e82f984f993e9d8debf 201 SMART SM01120 31 198 2.1E-76 T 29-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 SMALA_RS03765 b548b09ba7697e82f984f993e9d8debf 201 Pfam PF02734 DAK2 domain 31 197 4.5E-53 T 29-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 SMALA_RS03765 b548b09ba7697e82f984f993e9d8debf 201 TIGRFAM TIGR02365 dha_L_ycgS: dihydroxyacetone kinase, L subunit 8 197 1.3E-70 T 29-03-2018 IPR012737 Dihydroxyacetone kinase, subunit L GO:0016772 SMALA_RS03765 b548b09ba7697e82f984f993e9d8debf 201 SUPERFAMILY SSF101473 2 199 4.58E-57 T 29-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 SMALA_RS27875 1d40dffc9ab20ab4664e60b4b11b07bb 495 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 10 328 7.4E-91 T 29-03-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 SMALA_RS27875 1d40dffc9ab20ab4664e60b4b11b07bb 495 PRINTS PR00987 Glutamyl-tRNA synthetase signature 42 55 2.9E-22 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 SMALA_RS27875 1d40dffc9ab20ab4664e60b4b11b07bb 495 PRINTS PR00987 Glutamyl-tRNA synthetase signature 13 25 2.9E-22 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 SMALA_RS27875 1d40dffc9ab20ab4664e60b4b11b07bb 495 PRINTS PR00987 Glutamyl-tRNA synthetase signature 27 38 2.9E-22 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 SMALA_RS27875 1d40dffc9ab20ab4664e60b4b11b07bb 495 PRINTS PR00987 Glutamyl-tRNA synthetase signature 198 208 2.9E-22 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 SMALA_RS27875 1d40dffc9ab20ab4664e60b4b11b07bb 495 PRINTS PR00987 Glutamyl-tRNA synthetase signature 214 222 2.9E-22 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 SMALA_RS27875 1d40dffc9ab20ab4664e60b4b11b07bb 495 SUPERFAMILY SSF48163 325 490 5.49E-34 T 29-03-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 SMALA_RS27875 1d40dffc9ab20ab4664e60b4b11b07bb 495 Gene3D G3DSA:1.10.10.350 396 495 7.4E-26 T 29-03-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 SMALA_RS27875 1d40dffc9ab20ab4664e60b4b11b07bb 495 Gene3D G3DSA:3.40.50.620 10 130 2.5E-37 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS27875 1d40dffc9ab20ab4664e60b4b11b07bb 495 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 10 488 1.5E-143 T 29-03-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 SMALA_RS27875 1d40dffc9ab20ab4664e60b4b11b07bb 495 Gene3D G3DSA:1.10.1160.10 257 340 7.7E-29 T 29-03-2018 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 SMALA_RS27875 1d40dffc9ab20ab4664e60b4b11b07bb 495 SUPERFAMILY SSF52374 10 324 6.97E-105 T 29-03-2018 SMALA_RS27875 1d40dffc9ab20ab4664e60b4b11b07bb 495 Gene3D G3DSA:3.40.50.620 131 256 3.9E-25 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS27875 1d40dffc9ab20ab4664e60b4b11b07bb 495 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 9 490 31.955 T 29-03-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 SMALA_RS39705 4627e51b9cac5161012fb327d0a528e9 248 SMART SM00116 95 143 3.3E-5 T 29-03-2018 IPR000644 CBS domain SMALA_RS39705 4627e51b9cac5161012fb327d0a528e9 248 SMART SM00116 13 61 5.9E-6 T 29-03-2018 IPR000644 CBS domain SMALA_RS39705 4627e51b9cac5161012fb327d0a528e9 248 Gene3D G3DSA:3.10.580.10 1 73 5.2E-15 T 29-03-2018 SMALA_RS39705 4627e51b9cac5161012fb327d0a528e9 248 Gene3D G3DSA:3.10.580.10 74 220 1.4E-14 T 29-03-2018 SMALA_RS39705 4627e51b9cac5161012fb327d0a528e9 248 PIRSF PIRSF036990 4 228 3.6E-50 T 29-03-2018 IPR017080 Uncharacterised conserved protein UCP036990, CBS, BON SMALA_RS39705 4627e51b9cac5161012fb327d0a528e9 248 Pfam PF04972 BON domain 146 210 2.3E-9 T 29-03-2018 IPR007055 BON domain SMALA_RS39705 4627e51b9cac5161012fb327d0a528e9 248 Pfam PF00571 CBS domain 91 140 4.3E-11 T 29-03-2018 IPR000644 CBS domain SMALA_RS39705 4627e51b9cac5161012fb327d0a528e9 248 Pfam PF00571 CBS domain 6 58 1.5E-12 T 29-03-2018 IPR000644 CBS domain SMALA_RS39705 4627e51b9cac5161012fb327d0a528e9 248 SUPERFAMILY SSF54631 2 140 1.73E-28 T 29-03-2018 SMALA_RS39875 9b9ff2fc7b7f86438be7a72bbca06df9 386 Gene3D G3DSA:3.30.565.10 252 376 4.5E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS39875 9b9ff2fc7b7f86438be7a72bbca06df9 386 Pfam PF07730 Histidine kinase 174 239 1.4E-19 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMALA_RS39875 9b9ff2fc7b7f86438be7a72bbca06df9 386 SMART SM00387 283 376 8.4E-6 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS39875 9b9ff2fc7b7f86438be7a72bbca06df9 386 SUPERFAMILY SSF55874 262 374 1.23E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS16855 96e4a2b2160b303d22f7771448980715 295 Hamap MF_01576 Bifunctional protein FolD [folD]. 3 283 35.489 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 SMALA_RS16855 96e4a2b2160b303d22f7771448980715 295 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 5 120 3.1E-34 T 29-03-2018 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 SMALA_RS16855 96e4a2b2160b303d22f7771448980715 295 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 123 282 1.3E-58 T 29-03-2018 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0004488 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 SMALA_RS16855 96e4a2b2160b303d22f7771448980715 295 Gene3D G3DSA:3.40.50.10860 11 138 1.4E-40 T 29-03-2018 SMALA_RS16855 96e4a2b2160b303d22f7771448980715 295 Gene3D G3DSA:3.40.50.720 139 264 6.3E-29 T 29-03-2018 SMALA_RS16855 96e4a2b2160b303d22f7771448980715 295 SUPERFAMILY SSF51735 122 282 5.79E-39 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS16855 96e4a2b2160b303d22f7771448980715 295 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 154 174 3.0E-58 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 SMALA_RS16855 96e4a2b2160b303d22f7771448980715 295 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 33 55 3.0E-58 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 SMALA_RS16855 96e4a2b2160b303d22f7771448980715 295 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 74 101 3.0E-58 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 SMALA_RS16855 96e4a2b2160b303d22f7771448980715 295 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 109 130 3.0E-58 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 SMALA_RS16855 96e4a2b2160b303d22f7771448980715 295 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 256 274 3.0E-58 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 SMALA_RS16855 96e4a2b2160b303d22f7771448980715 295 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 205 234 3.0E-58 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 SMALA_RS16855 96e4a2b2160b303d22f7771448980715 295 SUPERFAMILY SSF53223 1 121 2.69E-36 T 29-03-2018 SMALA_RS23960 7caa763b0c389dae366bbfcec81ef7e6 308 SUPERFAMILY SSF54211 4 161 9.87E-40 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SMALA_RS23960 7caa763b0c389dae366bbfcec81ef7e6 308 Gene3D G3DSA:3.30.70.890 164 300 4.5E-33 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain SMALA_RS23960 7caa763b0c389dae366bbfcec81ef7e6 308 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 5 280 2.0E-47 T 29-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 SMALA_RS23960 7caa763b0c389dae366bbfcec81ef7e6 308 Pfam PF00288 GHMP kinases N terminal domain 89 147 7.1E-6 T 29-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 SMALA_RS23960 7caa763b0c389dae366bbfcec81ef7e6 308 Gene3D G3DSA:3.30.230.10 5 162 1.1E-44 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SMALA_RS23960 7caa763b0c389dae366bbfcec81ef7e6 308 PIRSF PIRSF010376 3 304 8.8E-76 T 29-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 SMALA_RS23960 7caa763b0c389dae366bbfcec81ef7e6 308 Hamap MF_00061 Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 5 298 29.774 T 29-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 SMALA_RS23960 7caa763b0c389dae366bbfcec81ef7e6 308 Pfam PF08544 GHMP kinases C terminal 212 288 2.8E-9 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain SMALA_RS23960 7caa763b0c389dae366bbfcec81ef7e6 308 SUPERFAMILY SSF55060 167 294 5.18E-23 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain SMALA_RS38060 2388ea1b77717567729e7103359f0821 238 SUPERFAMILY SSF46785 6 74 2.42E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS38060 2388ea1b77717567729e7103359f0821 238 SMART SM00866 89 228 1.6E-7 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMALA_RS38060 2388ea1b77717567729e7103359f0821 238 Pfam PF00392 Bacterial regulatory proteins, gntR family 9 70 2.8E-17 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS38060 2388ea1b77717567729e7103359f0821 238 SUPERFAMILY SSF64288 58 231 1.32E-22 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMALA_RS38060 2388ea1b77717567729e7103359f0821 238 SMART SM00345 11 70 3.2E-17 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS38060 2388ea1b77717567729e7103359f0821 238 Gene3D G3DSA:1.10.10.10 2 72 4.9E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS38060 2388ea1b77717567729e7103359f0821 238 Gene3D G3DSA:3.40.1410.10 76 236 1.4E-24 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMALA_RS38060 2388ea1b77717567729e7103359f0821 238 Pfam PF07702 UTRA domain 89 228 1.7E-19 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMALA_RS38060 2388ea1b77717567729e7103359f0821 238 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 44 60 3.6E-9 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS38060 2388ea1b77717567729e7103359f0821 238 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 30 44 3.6E-9 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS01740 7420f7b5122967120a0901f0c73d2918 960 Gene3D G3DSA:3.30.450.40 391 565 7.0E-22 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS01740 7420f7b5122967120a0901f0c73d2918 960 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 618 758 9.9E-46 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS01740 7420f7b5122967120a0901f0c73d2918 960 SMART SM00086 236 278 8.9E-6 T 29-03-2018 IPR001610 PAC motif SMALA_RS01740 7420f7b5122967120a0901f0c73d2918 960 SUPERFAMILY SSF55785 169 279 5.06E-18 T 29-03-2018 IPR000014 PAS domain SMALA_RS01740 7420f7b5122967120a0901f0c73d2918 960 SUPERFAMILY SSF55785 282 384 5.93E-9 T 29-03-2018 IPR000014 PAS domain SMALA_RS01740 7420f7b5122967120a0901f0c73d2918 960 Gene3D G3DSA:3.30.450.20 287 390 7.3E-15 T 29-03-2018 SMALA_RS01740 7420f7b5122967120a0901f0c73d2918 960 Gene3D G3DSA:3.60.40.10 566 830 9.6E-41 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS01740 7420f7b5122967120a0901f0c73d2918 960 Pfam PF08448 PAS fold 292 387 1.0E-7 T 29-03-2018 IPR013656 PAS fold-4 SMALA_RS01740 7420f7b5122967120a0901f0c73d2918 960 Gene3D G3DSA:3.30.565.10 834 959 5.4E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS01740 7420f7b5122967120a0901f0c73d2918 960 SMART SM00331 590 827 8.1E-31 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS01740 7420f7b5122967120a0901f0c73d2918 960 SMART SM00065 406 569 8.3E-5 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS01740 7420f7b5122967120a0901f0c73d2918 960 Pfam PF08447 PAS fold 186 270 1.1E-18 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 SMALA_RS01740 7420f7b5122967120a0901f0c73d2918 960 SMART SM00091 163 230 0.04 T 29-03-2018 IPR000014 PAS domain SMALA_RS01740 7420f7b5122967120a0901f0c73d2918 960 SMART SM00091 283 347 0.0061 T 29-03-2018 IPR000014 PAS domain SMALA_RS01740 7420f7b5122967120a0901f0c73d2918 960 Pfam PF13185 GAF domain 419 559 1.3E-9 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS01740 7420f7b5122967120a0901f0c73d2918 960 SUPERFAMILY SSF81606 604 753 5.75E-6 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS01740 7420f7b5122967120a0901f0c73d2918 960 Pfam PF13581 Histidine kinase-like ATPase domain 850 948 7.7E-7 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS01740 7420f7b5122967120a0901f0c73d2918 960 Gene3D G3DSA:3.30.450.20 142 286 6.8E-19 T 29-03-2018 SMALA_RS01740 7420f7b5122967120a0901f0c73d2918 960 Gene3D G3DSA:3.30.450.40 1 141 6.5E-8 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS01740 7420f7b5122967120a0901f0c73d2918 960 SUPERFAMILY SSF55781 422 570 3.27E-14 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS20770 b9c4c70fc45581292556552c87d4aa8b 402 Pfam PF00266 Aminotransferase class-V 79 323 2.9E-13 T 29-03-2018 IPR000192 Aminotransferase class V domain SMALA_RS20770 b9c4c70fc45581292556552c87d4aa8b 402 PIRSF PIRSF038800 5 402 3.1E-130 T 29-03-2018 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 SMALA_RS20770 b9c4c70fc45581292556552c87d4aa8b 402 Gene3D G3DSA:3.90.1150.10 298 402 5.5E-18 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS20770 b9c4c70fc45581292556552c87d4aa8b 402 SUPERFAMILY SSF53383 12 401 8.17E-75 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS20770 b9c4c70fc45581292556552c87d4aa8b 402 Gene3D G3DSA:3.40.640.10 44 297 5.4E-38 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS20770 b9c4c70fc45581292556552c87d4aa8b 402 TIGRFAM TIGR01814 kynureninase: kynureninase 12 399 1.3E-79 T 29-03-2018 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 SMALA_RS20770 b9c4c70fc45581292556552c87d4aa8b 402 Hamap MF_01970 Kynureninase [kynU]. 2 399 33.676 T 29-03-2018 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 SMALA_RS41085 cd3928fb32592397e67c6d0c16bf0909 301 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 2.7E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS41085 cd3928fb32592397e67c6d0c16bf0909 301 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 2.7E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS41085 cd3928fb32592397e67c6d0c16bf0909 301 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 2.7E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS41085 cd3928fb32592397e67c6d0c16bf0909 301 Gene3D G3DSA:3.40.50.720 1 301 2.7E-54 T 29-03-2018 SMALA_RS41085 cd3928fb32592397e67c6d0c16bf0909 301 Pfam PF00106 short chain dehydrogenase 16 216 1.1E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS41085 cd3928fb32592397e67c6d0c16bf0909 301 SUPERFAMILY SSF51735 13 250 5.03E-48 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS25755 ff2ee450941981b36cb969da04f642e5 373 Pfam PF00155 Aminotransferase class I and II 30 371 3.6E-46 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMALA_RS25755 ff2ee450941981b36cb969da04f642e5 373 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 229 242 - T 29-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 SMALA_RS25755 ff2ee450941981b36cb969da04f642e5 373 Gene3D G3DSA:3.40.640.10 64 276 1.0E-38 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS25755 ff2ee450941981b36cb969da04f642e5 373 SUPERFAMILY SSF53383 7 372 2.18E-80 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS25755 ff2ee450941981b36cb969da04f642e5 373 Gene3D G3DSA:3.90.1150.10 277 373 8.6E-23 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS25755 ff2ee450941981b36cb969da04f642e5 373 TIGRFAM TIGR03539 DapC_actino: succinyldiaminopimelate transaminase 8 371 7.1E-178 T 29-03-2018 IPR019880 Succinyldiaminopimelate transaminase, DapC, actinobacteria SMALA_RS09025 c1dbf32a14920e09c513f5171755f6f8 343 Gene3D G3DSA:3.20.20.70 12 343 2.0E-80 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS09025 c1dbf32a14920e09c513f5171755f6f8 343 Pfam PF13353 4Fe-4S single cluster domain 32 119 1.5E-6 T 29-03-2018 SMALA_RS09025 c1dbf32a14920e09c513f5171755f6f8 343 Hamap MF_01225_B GTP 3',8-cyclase [moaA]. 16 343 40.871 T 29-03-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 Reactome: R-HSA-947581 SMALA_RS09025 c1dbf32a14920e09c513f5171755f6f8 343 SMART SM00729 25 227 2.8E-10 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 SMALA_RS09025 c1dbf32a14920e09c513f5171755f6f8 343 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 16 343 2.7E-110 T 29-03-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 Reactome: R-HSA-947581 SMALA_RS09025 c1dbf32a14920e09c513f5171755f6f8 343 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 31 42 - T 29-03-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 Reactome: R-HSA-947581 SMALA_RS09025 c1dbf32a14920e09c513f5171755f6f8 343 Pfam PF06463 Molybdenum Cofactor Synthesis C 197 323 5.7E-36 T 29-03-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 Reactome: R-HSA-947581 SMALA_RS09025 c1dbf32a14920e09c513f5171755f6f8 343 Pfam PF04055 Radical SAM superfamily 30 191 5.5E-33 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 SMALA_RS09025 c1dbf32a14920e09c513f5171755f6f8 343 SUPERFAMILY SSF102114 16 291 7.59E-72 T 29-03-2018 SMALA_RS31030 f69540d04d4bc5dedf39377d96047a00 396 SUPERFAMILY SSF55781 278 385 1.11E-5 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS31030 f69540d04d4bc5dedf39377d96047a00 396 Gene3D G3DSA:3.30.450.40 203 388 1.1E-10 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS31030 f69540d04d4bc5dedf39377d96047a00 396 Gene3D G3DSA:3.30.450.20 72 187 1.4E-12 T 29-03-2018 SMALA_RS31030 f69540d04d4bc5dedf39377d96047a00 396 Pfam PF08448 PAS fold 82 175 2.6E-7 T 29-03-2018 IPR013656 PAS fold-4 SMALA_RS31030 f69540d04d4bc5dedf39377d96047a00 396 SUPERFAMILY SSF55785 74 165 4.38E-9 T 29-03-2018 IPR000014 PAS domain SMALA_RS00610 c878170bd0e39a00b8aa30ce9138a95c 406 Gene3D G3DSA:3.50.50.60 98 234 2.4E-29 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS00610 c878170bd0e39a00b8aa30ce9138a95c 406 Gene3D G3DSA:3.50.50.60 239 321 5.9E-5 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS00610 c878170bd0e39a00b8aa30ce9138a95c 406 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 1 295 1.1E-51 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS00610 c878170bd0e39a00b8aa30ce9138a95c 406 SUPERFAMILY SSF51905 140 332 7.34E-29 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS00610 c878170bd0e39a00b8aa30ce9138a95c 406 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 252 274 6.4E-15 T 29-03-2018 SMALA_RS00610 c878170bd0e39a00b8aa30ce9138a95c 406 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 228 244 6.4E-15 T 29-03-2018 SMALA_RS00610 c878170bd0e39a00b8aa30ce9138a95c 406 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 142 160 6.4E-15 T 29-03-2018 SMALA_RS00610 c878170bd0e39a00b8aa30ce9138a95c 406 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 96 114 6.4E-15 T 29-03-2018 SMALA_RS00610 c878170bd0e39a00b8aa30ce9138a95c 406 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 262 280 1.3E-5 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMALA_RS00610 c878170bd0e39a00b8aa30ce9138a95c 406 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 138 162 1.3E-5 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMALA_RS00610 c878170bd0e39a00b8aa30ce9138a95c 406 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 97 105 1.3E-5 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMALA_RS00610 c878170bd0e39a00b8aa30ce9138a95c 406 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 230 251 1.3E-5 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMALA_RS00610 c878170bd0e39a00b8aa30ce9138a95c 406 Pfam PF14759 Reductase C-terminal 316 391 4.3E-12 T 29-03-2018 IPR028202 Reductase, C-terminal SMALA_RS00610 c878170bd0e39a00b8aa30ce9138a95c 406 SUPERFAMILY SSF55424 308 388 3.11E-19 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SMALA_RS00610 c878170bd0e39a00b8aa30ce9138a95c 406 Gene3D G3DSA:3.50.50.60 1 97 1.7E-11 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS00610 c878170bd0e39a00b8aa30ce9138a95c 406 SUPERFAMILY SSF51905 1 187 1.64E-40 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS00610 c878170bd0e39a00b8aa30ce9138a95c 406 Gene3D G3DSA:3.30.390.30 322 404 1.2E-21 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SMALA_RS06530 d8ac63e17b32edf2e291bbbf6988fd2e 415 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 357 366 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMALA_RS06530 d8ac63e17b32edf2e291bbbf6988fd2e 415 Gene3D G3DSA:1.10.630.10 5 414 1.8E-53 T 29-03-2018 SMALA_RS06530 d8ac63e17b32edf2e291bbbf6988fd2e 415 SUPERFAMILY SSF48264 9 413 2.1E-66 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS06530 d8ac63e17b32edf2e291bbbf6988fd2e 415 Pfam PF00067 Cytochrome P450 286 378 4.7E-16 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS18710 8ae606cd901cea31eb51e8905ca7404d 191 Pfam PF02342 TerD domain 3 187 1.7E-84 T 29-03-2018 IPR003325 TerD domain GO:0006950 SMALA_RS18710 8ae606cd901cea31eb51e8905ca7404d 191 Gene3D G3DSA:2.60.60.30 19 186 7.2E-67 T 29-03-2018 SMALA_RS26820 8650ff0369c5cc944b65cb9bbcaedf87 463 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 93 111 - T 29-03-2018 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site SMALA_RS26820 8650ff0369c5cc944b65cb9bbcaedf87 463 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 42 461 4.8E-143 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMALA_RS26820 8650ff0369c5cc944b65cb9bbcaedf87 463 SUPERFAMILY SSF50621 302 462 1.88E-48 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 SMALA_RS26820 8650ff0369c5cc944b65cb9bbcaedf87 463 PRINTS PR01181 Diaminopimelate decarboxylase signature 200 209 2.0E-24 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMALA_RS26820 8650ff0369c5cc944b65cb9bbcaedf87 463 PRINTS PR01181 Diaminopimelate decarboxylase signature 111 128 2.0E-24 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMALA_RS26820 8650ff0369c5cc944b65cb9bbcaedf87 463 PRINTS PR01181 Diaminopimelate decarboxylase signature 346 364 2.0E-24 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMALA_RS26820 8650ff0369c5cc944b65cb9bbcaedf87 463 PRINTS PR01181 Diaminopimelate decarboxylase signature 429 451 2.0E-24 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMALA_RS26820 8650ff0369c5cc944b65cb9bbcaedf87 463 Gene3D G3DSA:2.40.37.10 313 462 3.2E-40 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 SMALA_RS26820 8650ff0369c5cc944b65cb9bbcaedf87 463 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 72 327 1.2E-67 T 29-03-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 SMALA_RS26820 8650ff0369c5cc944b65cb9bbcaedf87 463 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 333 419 2.7E-14 T 29-03-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 SMALA_RS26820 8650ff0369c5cc944b65cb9bbcaedf87 463 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 419 432 5.1E-17 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMALA_RS26820 8650ff0369c5cc944b65cb9bbcaedf87 463 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 113 125 5.1E-17 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMALA_RS26820 8650ff0369c5cc944b65cb9bbcaedf87 463 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 317 336 5.1E-17 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMALA_RS26820 8650ff0369c5cc944b65cb9bbcaedf87 463 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 93 111 5.1E-17 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMALA_RS26820 8650ff0369c5cc944b65cb9bbcaedf87 463 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 228 241 5.1E-17 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMALA_RS26820 8650ff0369c5cc944b65cb9bbcaedf87 463 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 52 462 39.286 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMALA_RS26820 8650ff0369c5cc944b65cb9bbcaedf87 463 SUPERFAMILY SSF51419 63 328 2.04E-77 T 29-03-2018 IPR029066 PLP-binding barrel SMALA_RS26820 8650ff0369c5cc944b65cb9bbcaedf87 463 Gene3D G3DSA:3.20.20.10 71 312 7.0E-67 T 29-03-2018 IPR029066 PLP-binding barrel SMALA_RS26820 8650ff0369c5cc944b65cb9bbcaedf87 463 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 267 280 - T 29-03-2018 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site SMALA_RS04875 c8e5f1d1861db08d5994f4d638dd7a19 567 Pfam PF00501 AMP-binding enzyme 59 447 1.6E-67 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS04875 c8e5f1d1861db08d5994f4d638dd7a19 567 Gene3D G3DSA:2.30.38.10 360 440 7.2E-11 T 29-03-2018 SMALA_RS04875 c8e5f1d1861db08d5994f4d638dd7a19 567 Gene3D G3DSA:3.30.300.30 441 554 7.4E-28 T 29-03-2018 SMALA_RS04875 c8e5f1d1861db08d5994f4d638dd7a19 567 ProSitePatterns PS00455 Putative AMP-binding domain signature. 206 217 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS04875 c8e5f1d1861db08d5994f4d638dd7a19 567 Gene3D G3DSA:3.40.50.980 44 211 1.3E-28 T 29-03-2018 SMALA_RS04875 c8e5f1d1861db08d5994f4d638dd7a19 567 SUPERFAMILY SSF56801 29 547 2.22E-120 T 29-03-2018 SMALA_RS04875 c8e5f1d1861db08d5994f4d638dd7a19 567 Gene3D G3DSA:3.40.50.980 212 359 1.9E-31 T 29-03-2018 SMALA_RS04875 c8e5f1d1861db08d5994f4d638dd7a19 567 Pfam PF13193 AMP-binding enzyme C-terminal domain 456 534 5.3E-22 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS40290 152cee9dcb1417ca406d769463f501ef 116 SMART SM00418 11 89 1.7E-26 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS40290 152cee9dcb1417ca406d769463f501ef 116 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 1.8E-8 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS40290 152cee9dcb1417ca406d769463f501ef 116 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 13 28 1.8E-8 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS40290 152cee9dcb1417ca406d769463f501ef 116 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 45 60 1.8E-8 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS40290 152cee9dcb1417ca406d769463f501ef 116 Pfam PF12840 Helix-turn-helix domain 11 68 4.9E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS40290 152cee9dcb1417ca406d769463f501ef 116 SUPERFAMILY SSF46785 4 89 1.41E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS40290 152cee9dcb1417ca406d769463f501ef 116 Gene3D G3DSA:1.10.10.10 5 87 7.7E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS27985 6addc274902b0ec1d13a88b9c8c563d2 580 Pfam PF13684 Dihydroxyacetone kinase family 253 580 1.1E-79 T 29-03-2018 IPR033470 Uncharacterised protein, DhaK domain SMALA_RS27985 6addc274902b0ec1d13a88b9c8c563d2 580 Pfam PF02734 DAK2 domain 35 212 1.7E-26 T 29-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 SMALA_RS27985 6addc274902b0ec1d13a88b9c8c563d2 580 SMART SM01121 252 580 2.3E-96 T 29-03-2018 IPR033470 Uncharacterised protein, DhaK domain SMALA_RS27985 6addc274902b0ec1d13a88b9c8c563d2 580 SMART SM01120 35 213 1.6E-44 T 29-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 SMALA_RS27985 6addc274902b0ec1d13a88b9c8c563d2 580 SUPERFAMILY SSF101473 5 215 1.83E-30 T 29-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 SMALA_RS27985 6addc274902b0ec1d13a88b9c8c563d2 580 TIGRFAM TIGR03599 YloV: DAK2 domain fusion protein YloV 11 580 2.1E-133 T 29-03-2018 IPR019986 DAK2 domain-containing protein YloV SMALA_RS43200 eca77456e54b5cc98587fa23abfc25ae 1731 SUPERFAMILY SSF52540 794 954 7.7E-15 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS43200 eca77456e54b5cc98587fa23abfc25ae 1731 SUPERFAMILY SSF52540 697 759 7.7E-15 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS43200 eca77456e54b5cc98587fa23abfc25ae 1731 Pfam PF08751 TrwC relaxase 38 401 2.1E-51 T 29-03-2018 IPR014862 TrwC relaxase SMALA_RS43200 eca77456e54b5cc98587fa23abfc25ae 1731 Pfam PF13604 AAA domain 575 775 2.2E-47 T 29-03-2018 SMALA_RS43200 eca77456e54b5cc98587fa23abfc25ae 1731 Gene3D G3DSA:3.40.50.300 438 739 1.5E-21 T 29-03-2018 SMALA_RS43200 eca77456e54b5cc98587fa23abfc25ae 1731 SUPERFAMILY SSF52540 570 728 1.21E-23 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS43200 eca77456e54b5cc98587fa23abfc25ae 1731 SUPERFAMILY SSF55464 38 103 4.58E-31 T 29-03-2018 SMALA_RS43200 eca77456e54b5cc98587fa23abfc25ae 1731 SUPERFAMILY SSF55464 169 392 4.58E-31 T 29-03-2018 SMALA_RS43200 eca77456e54b5cc98587fa23abfc25ae 1731 SMART SM00382 589 823 0.0043 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS20530 bdf1915f6d158f3b26a848078eae81cc 111 Pfam PF01022 Bacterial regulatory protein, arsR family 20 64 1.3E-14 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS20530 bdf1915f6d158f3b26a848078eae81cc 111 SUPERFAMILY SSF46785 6 89 5.93E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS20530 bdf1915f6d158f3b26a848078eae81cc 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 62 77 2.4E-8 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS20530 bdf1915f6d158f3b26a848078eae81cc 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 47 62 2.4E-8 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS20530 bdf1915f6d158f3b26a848078eae81cc 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 15 30 2.4E-8 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS20530 bdf1915f6d158f3b26a848078eae81cc 111 Gene3D G3DSA:1.10.10.10 3 108 2.0E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS20530 bdf1915f6d158f3b26a848078eae81cc 111 SMART SM00418 13 91 2.1E-27 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS25180 5874922c198ea793448955953966ec53 189 Gene3D G3DSA:1.10.10.60 2 83 4.9E-9 T 29-03-2018 SMALA_RS25180 5874922c198ea793448955953966ec53 189 SUPERFAMILY SSF46689 7 72 3.74E-9 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS25180 5874922c198ea793448955953966ec53 189 SUPERFAMILY SSF48498 76 182 1.04E-17 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS25180 5874922c198ea793448955953966ec53 189 Gene3D G3DSA:1.10.357.10 84 189 3.0E-21 T 29-03-2018 SMALA_RS17885 af12fb432ee11c44bd55f62c845c3d5c 310 TIGRFAM TIGR03448 mycothiol_MshD: mycothiol synthase 18 306 2.3E-115 T 29-03-2018 IPR017813 Mycothiol acetyltransferase GO:0016747 SMALA_RS17885 af12fb432ee11c44bd55f62c845c3d5c 310 PIRSF PIRSF021524 9 310 1.2E-109 T 29-03-2018 IPR017813 Mycothiol acetyltransferase GO:0016747 SMALA_RS17885 af12fb432ee11c44bd55f62c845c3d5c 310 Hamap MF_01698 Mycothiol acetyltransferase [mshD]. 14 308 36.077 T 29-03-2018 IPR017813 Mycothiol acetyltransferase GO:0016747 SMALA_RS17885 af12fb432ee11c44bd55f62c845c3d5c 310 Gene3D G3DSA:3.40.630.30 102 154 0.003 T 29-03-2018 SMALA_RS17885 af12fb432ee11c44bd55f62c845c3d5c 310 Gene3D G3DSA:3.40.630.30 162 246 9.2E-15 T 29-03-2018 SMALA_RS17885 af12fb432ee11c44bd55f62c845c3d5c 310 SUPERFAMILY SSF55729 15 306 2.03E-46 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS17885 af12fb432ee11c44bd55f62c845c3d5c 310 Gene3D G3DSA:3.40.630.30 247 307 1.2E-16 T 29-03-2018 SMALA_RS17885 af12fb432ee11c44bd55f62c845c3d5c 310 Pfam PF00583 Acetyltransferase (GNAT) family 55 111 3.3E-4 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SMALA_RS17885 af12fb432ee11c44bd55f62c845c3d5c 310 Pfam PF00583 Acetyltransferase (GNAT) family 206 297 5.2E-16 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SMALA_RS17885 af12fb432ee11c44bd55f62c845c3d5c 310 Gene3D G3DSA:3.40.630.30 16 101 6.5E-7 T 29-03-2018 SMALA_RS27115 7d7856c15117045765124647e27860c3 169 ProSitePatterns PS01117 MarR-type HTH domain signature. 89 123 - T 29-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site SMALA_RS27115 7d7856c15117045765124647e27860c3 169 Pfam PF12802 MarR family 53 114 9.6E-12 T 29-03-2018 SMALA_RS27115 7d7856c15117045765124647e27860c3 169 SMART SM00347 48 149 1.1E-20 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS27115 7d7856c15117045765124647e27860c3 169 Gene3D G3DSA:1.10.10.10 24 169 3.0E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS27115 7d7856c15117045765124647e27860c3 169 SUPERFAMILY SSF46785 25 160 5.56E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS18000 21de2e53cb576cf9a4506aa3c07643a7 600 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 356 378 1.6E-10 T 29-03-2018 SMALA_RS18000 21de2e53cb576cf9a4506aa3c07643a7 600 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 14 33 1.6E-10 T 29-03-2018 SMALA_RS18000 21de2e53cb576cf9a4506aa3c07643a7 600 Pfam PF00890 FAD binding domain 13 393 1.2E-96 T 29-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMALA_RS18000 21de2e53cb576cf9a4506aa3c07643a7 600 SUPERFAMILY SSF51905 5 265 4.82E-66 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS18000 21de2e53cb576cf9a4506aa3c07643a7 600 SUPERFAMILY SSF51905 357 409 4.82E-66 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS18000 21de2e53cb576cf9a4506aa3c07643a7 600 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 11 414 2.2E-148 T 29-03-2018 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 SMALA_RS18000 21de2e53cb576cf9a4506aa3c07643a7 600 SUPERFAMILY SSF46977 469 579 3.4E-30 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMALA_RS18000 21de2e53cb576cf9a4506aa3c07643a7 600 Pfam PF02910 Fumarate reductase flavoprotein C-term 471 584 1.3E-19 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMALA_RS18000 21de2e53cb576cf9a4506aa3c07643a7 600 Gene3D G3DSA:1.20.58.100 454 549 2.7E-27 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMALA_RS18000 21de2e53cb576cf9a4506aa3c07643a7 600 PIRSF PIRSF000171 8 584 5.4E-41 T 29-03-2018 SMALA_RS18000 21de2e53cb576cf9a4506aa3c07643a7 600 SUPERFAMILY SSF56425 236 353 1.23E-37 T 29-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMALA_RS18000 21de2e53cb576cf9a4506aa3c07643a7 600 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 13 35 3.4E-6 T 29-03-2018 SMALA_RS18000 21de2e53cb576cf9a4506aa3c07643a7 600 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 371 378 3.4E-6 T 29-03-2018 SMALA_RS18000 21de2e53cb576cf9a4506aa3c07643a7 600 Gene3D G3DSA:3.50.50.60 7 306 5.2E-46 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS18000 21de2e53cb576cf9a4506aa3c07643a7 600 Gene3D G3DSA:3.50.50.60 307 409 1.4E-17 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS18000 21de2e53cb576cf9a4506aa3c07643a7 600 Gene3D G3DSA:4.10.80.40 550 585 2.7E-4 T 29-03-2018 SMALA_RS37955 d41064459c309f0edc4cf830998d7dcb 185 Gene3D G3DSA:3.10.20.30 4 80 6.4E-29 T 29-03-2018 IPR012675 Beta-grasp domain SMALA_RS37955 d41064459c309f0edc4cf830998d7dcb 185 Pfam PF01799 [2Fe-2S] binding domain 79 169 1.2E-29 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 SMALA_RS37955 d41064459c309f0edc4cf830998d7dcb 185 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 45 53 - T 29-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 SMALA_RS37955 d41064459c309f0edc4cf830998d7dcb 185 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 12 59 4.0E-9 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SMALA_RS37955 d41064459c309f0edc4cf830998d7dcb 185 Gene3D G3DSA:1.10.150.120 81 184 7.4E-35 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 SMALA_RS37955 d41064459c309f0edc4cf830998d7dcb 185 SUPERFAMILY SSF47741 90 175 5.23E-28 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 SMALA_RS37955 d41064459c309f0edc4cf830998d7dcb 185 SUPERFAMILY SSF54292 9 94 1.97E-27 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SMALA_RS20075 a3139ec63840b506862dcc260f510021 285 SUPERFAMILY SSF47413 33 79 7.11E-5 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS20075 a3139ec63840b506862dcc260f510021 285 Gene3D G3DSA:1.10.260.40 25 147 1.4E-5 T 29-03-2018 SMALA_RS04695 f573f191b51aaede502b9d5a69531796 1038 SUPERFAMILY SSF74650 614 1035 1.38E-57 T 29-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 SMALA_RS04695 f573f191b51aaede502b9d5a69531796 1038 Pfam PF01074 Glycosyl hydrolases family 38 N-terminal domain 254 511 1.1E-73 T 29-03-2018 IPR000602 Glycoside hydrolase family 38, N-terminal domain GO:0004559|GO:0006013 SMALA_RS04695 f573f191b51aaede502b9d5a69531796 1038 SUPERFAMILY SSF88713 248 515 8.9E-66 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 SMALA_RS04695 f573f191b51aaede502b9d5a69531796 1038 Gene3D G3DSA:3.20.110.10 205 456 9.6E-66 T 29-03-2018 IPR027291 Glycoside hydrolase 38/57, N-terminal domain SMALA_RS04695 f573f191b51aaede502b9d5a69531796 1038 Pfam PF09261 Alpha mannosidase middle domain 519 596 3.2E-24 T 29-03-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 SMALA_RS04695 f573f191b51aaede502b9d5a69531796 1038 SUPERFAMILY SSF88688 518 611 3.01E-24 T 29-03-2018 IPR028995 Glycoside hydrolase families 57/38, central domain SMALA_RS04695 f573f191b51aaede502b9d5a69531796 1038 Gene3D G3DSA:1.20.1270.50 518 617 3.0E-29 T 29-03-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 SMALA_RS04695 f573f191b51aaede502b9d5a69531796 1038 Pfam PF07748 Glycosyl hydrolases family 38 C-terminal domain 619 1032 4.4E-62 T 29-03-2018 IPR011682 Glycosyl hydrolase family 38, C-terminal GO:0004559|GO:0006013 SMALA_RS04695 f573f191b51aaede502b9d5a69531796 1038 SMART SM00872 518 596 5.0E-32 T 29-03-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 SMALA_RS38020 b8830a4191319e51234865347d92d6a6 309 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 305 2.7E-36 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS38020 b8830a4191319e51234865347d92d6a6 309 Gene3D G3DSA:1.10.3720.10 2 293 2.8E-35 T 29-03-2018 SMALA_RS38020 b8830a4191319e51234865347d92d6a6 309 SUPERFAMILY SSF161098 88 291 2.45E-15 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS16085 731f47bf6d8de43bc609d2b47eda8255 384 SMART SM00382 27 213 5.9E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS16085 731f47bf6d8de43bc609d2b47eda8255 384 Pfam PF00005 ABC transporter 19 163 6.3E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS16085 731f47bf6d8de43bc609d2b47eda8255 384 SUPERFAMILY SSF52540 1 239 7.27E-74 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS16085 731f47bf6d8de43bc609d2b47eda8255 384 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS16085 731f47bf6d8de43bc609d2b47eda8255 384 Gene3D G3DSA:3.40.50.300 1 380 3.5E-72 T 29-03-2018 SMALA_RS32380 fbf529cebccb6e8f5882c5b915798ddc 186 SUPERFAMILY SSF46689 12 73 5.64E-9 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS32380 fbf529cebccb6e8f5882c5b915798ddc 186 Gene3D G3DSA:1.10.357.10 64 186 1.4E-12 T 29-03-2018 SMALA_RS32380 fbf529cebccb6e8f5882c5b915798ddc 186 Gene3D G3DSA:1.10.10.60 1 63 3.7E-12 T 29-03-2018 SMALA_RS32380 fbf529cebccb6e8f5882c5b915798ddc 186 Pfam PF00440 Bacterial regulatory proteins, tetR family 29 67 6.6E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS32380 fbf529cebccb6e8f5882c5b915798ddc 186 SUPERFAMILY SSF48498 80 185 3.78E-16 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS32380 fbf529cebccb6e8f5882c5b915798ddc 186 Pfam PF16859 Bacterial transcriptional repressor C-terminal 79 182 7.7E-22 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS36725 a0f48f880cd86fd1229fe5e99b6c1cc9 288 PRINTS PR00412 Epoxide hydrolase signature 30 48 2.2E-5 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS36725 a0f48f880cd86fd1229fe5e99b6c1cc9 288 PRINTS PR00412 Epoxide hydrolase signature 255 277 2.2E-5 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS36725 a0f48f880cd86fd1229fe5e99b6c1cc9 288 PRINTS PR00412 Epoxide hydrolase signature 50 65 2.2E-5 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS36725 a0f48f880cd86fd1229fe5e99b6c1cc9 288 PRINTS PR00412 Epoxide hydrolase signature 94 107 2.2E-5 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS36725 a0f48f880cd86fd1229fe5e99b6c1cc9 288 PRINTS PR00111 Alpha/beta hydrolase fold signature 94 107 1.0E-6 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS36725 a0f48f880cd86fd1229fe5e99b6c1cc9 288 PRINTS PR00111 Alpha/beta hydrolase fold signature 50 65 1.0E-6 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS36725 a0f48f880cd86fd1229fe5e99b6c1cc9 288 PRINTS PR00111 Alpha/beta hydrolase fold signature 108 121 1.0E-6 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS36725 a0f48f880cd86fd1229fe5e99b6c1cc9 288 Pfam PF00561 alpha/beta hydrolase fold 25 149 2.3E-23 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS36725 a0f48f880cd86fd1229fe5e99b6c1cc9 288 Gene3D G3DSA:3.40.50.1820 1 281 7.7E-44 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS36725 a0f48f880cd86fd1229fe5e99b6c1cc9 288 SUPERFAMILY SSF53474 7 276 5.49E-45 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS18015 e272317b7f57308e84ea0e5252896e92 427 SUPERFAMILY SSF53383 96 358 1.07E-57 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS18015 e272317b7f57308e84ea0e5252896e92 427 Pfam PF01212 Beta-eliminating lyase 96 329 1.9E-24 T 29-03-2018 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 SMALA_RS18015 e272317b7f57308e84ea0e5252896e92 427 Gene3D G3DSA:3.40.640.10 89 314 1.9E-23 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS22465 37bea0ca01c17c91d0bb8378a15f6be7 1304 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 10 1256 0.0 T 29-03-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMALA_RS22465 37bea0ca01c17c91d0bb8378a15f6be7 1304 Pfam PF04983 RNA polymerase Rpb1, domain 3 564 736 9.9E-22 T 29-03-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMALA_RS22465 37bea0ca01c17c91d0bb8378a15f6be7 1304 Gene3D G3DSA:2.40.40.20 421 563 6.7E-40 T 29-03-2018 SMALA_RS22465 37bea0ca01c17c91d0bb8378a15f6be7 1304 Pfam PF04997 RNA polymerase Rpb1, domain 1 7 417 3.1E-82 T 29-03-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMALA_RS22465 37bea0ca01c17c91d0bb8378a15f6be7 1304 Pfam PF04998 RNA polymerase Rpb1, domain 5 843 1204 2.8E-67 T 29-03-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMALA_RS22465 37bea0ca01c17c91d0bb8378a15f6be7 1304 Gene3D G3DSA:2.40.50.100 986 1103 8.9E-41 T 29-03-2018 SMALA_RS22465 37bea0ca01c17c91d0bb8378a15f6be7 1304 SMART SM00663 310 589 4.1E-174 T 29-03-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMALA_RS22465 37bea0ca01c17c91d0bb8378a15f6be7 1304 Pfam PF00623 RNA polymerase Rpb1, domain 2 468 560 9.9E-28 T 29-03-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMALA_RS22465 37bea0ca01c17c91d0bb8378a15f6be7 1304 Pfam PF00623 RNA polymerase Rpb1, domain 2 419 480 1.3E-8 T 29-03-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMALA_RS22465 37bea0ca01c17c91d0bb8378a15f6be7 1304 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 4 1266 17.604 T 29-03-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMALA_RS22465 37bea0ca01c17c91d0bb8378a15f6be7 1304 Pfam PF05000 RNA polymerase Rpb1, domain 4 765 829 7.6E-14 T 29-03-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMALA_RS22465 37bea0ca01c17c91d0bb8378a15f6be7 1304 SUPERFAMILY SSF64484 5 1256 0.0 T 29-03-2018 SMALA_RS24270 c2ccf4b8f6f29b1e829f06245c3b7dc7 281 SUPERFAMILY SSF51120 144 276 1.22E-20 T 29-03-2018 IPR011049 Serralysin-like metalloprotease, C-terminal SMALA_RS24270 c2ccf4b8f6f29b1e829f06245c3b7dc7 281 Gene3D G3DSA:2.150.10.10 18 234 2.0E-13 T 29-03-2018 SMALA_RS24270 c2ccf4b8f6f29b1e829f06245c3b7dc7 281 Gene3D G3DSA:2.150.10.10 235 279 1.6E-14 T 29-03-2018 SMALA_RS24270 c2ccf4b8f6f29b1e829f06245c3b7dc7 281 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 145 157 0.98 T 29-03-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 SMALA_RS24270 c2ccf4b8f6f29b1e829f06245c3b7dc7 281 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 162 175 4.9 T 29-03-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 SMALA_RS24270 c2ccf4b8f6f29b1e829f06245c3b7dc7 281 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 243 260 5.4E-4 T 29-03-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 SMALA_RS24270 c2ccf4b8f6f29b1e829f06245c3b7dc7 281 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 182 190 8.0 T 29-03-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 SMALA_RS24270 c2ccf4b8f6f29b1e829f06245c3b7dc7 281 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 217 233 0.05 T 29-03-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 SMALA_RS24270 c2ccf4b8f6f29b1e829f06245c3b7dc7 281 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 199 215 0.011 T 29-03-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 SMALA_RS24270 c2ccf4b8f6f29b1e829f06245c3b7dc7 281 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 261 276 0.0021 T 29-03-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 SMALA_RS24270 c2ccf4b8f6f29b1e829f06245c3b7dc7 281 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 249 267 - T 29-03-2018 IPR018511 Hemolysin-type calcium-binding conserved site SMALA_RS24270 c2ccf4b8f6f29b1e829f06245c3b7dc7 281 PRINTS PR00313 NodO calcium binding signature 262 271 8.4E-10 T 29-03-2018 SMALA_RS24270 c2ccf4b8f6f29b1e829f06245c3b7dc7 281 PRINTS PR00313 NodO calcium binding signature 183 191 8.4E-10 T 29-03-2018 SMALA_RS24270 c2ccf4b8f6f29b1e829f06245c3b7dc7 281 PRINTS PR00313 NodO calcium binding signature 143 154 8.4E-10 T 29-03-2018 SMALA_RS24270 c2ccf4b8f6f29b1e829f06245c3b7dc7 281 PRINTS PR00313 NodO calcium binding signature 199 207 8.4E-10 T 29-03-2018 SMALA_RS37495 ba814154f5c5e5df7a4bbf38e871c5aa 263 Gene3D G3DSA:1.20.120.530 100 249 5.1E-30 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS37495 ba814154f5c5e5df7a4bbf38e871c5aa 263 SMART SM00895 108 229 9.2E-26 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS37495 ba814154f5c5e5df7a4bbf38e871c5aa 263 Pfam PF00392 Bacterial regulatory proteins, gntR family 21 84 6.9E-24 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS37495 ba814154f5c5e5df7a4bbf38e871c5aa 263 Gene3D G3DSA:1.10.10.10 15 86 4.8E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS37495 ba814154f5c5e5df7a4bbf38e871c5aa 263 Pfam PF07729 FCD domain 108 228 3.2E-27 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS37495 ba814154f5c5e5df7a4bbf38e871c5aa 263 SUPERFAMILY SSF46785 19 88 4.54E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS37495 ba814154f5c5e5df7a4bbf38e871c5aa 263 SMART SM00345 25 84 5.3E-25 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS37495 ba814154f5c5e5df7a4bbf38e871c5aa 263 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 44 58 1.3E-9 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS37495 ba814154f5c5e5df7a4bbf38e871c5aa 263 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 58 74 1.3E-9 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS37495 ba814154f5c5e5df7a4bbf38e871c5aa 263 SUPERFAMILY SSF48008 105 234 4.97E-31 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS33810 d5227a230b79d93b2f9b273606fb0f62 489 Pfam PF13183 4Fe-4S dicluster domain 308 377 1.5E-9 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain SMALA_RS33810 d5227a230b79d93b2f9b273606fb0f62 489 Gene3D G3DSA:3.30.70.20 371 407 0.24 T 29-03-2018 SMALA_RS33810 d5227a230b79d93b2f9b273606fb0f62 489 Gene3D G3DSA:3.30.70.20 320 370 2.0E-9 T 29-03-2018 SMALA_RS33810 d5227a230b79d93b2f9b273606fb0f62 489 Pfam PF11870 Domain of unknown function (DUF3390) 386 476 1.6E-14 T 29-03-2018 IPR024569 4Fe-4S binding protein, C-terminal SMALA_RS33810 d5227a230b79d93b2f9b273606fb0f62 489 Gene3D G3DSA:3.40.50.10420 137 293 3.5E-39 T 29-03-2018 SMALA_RS33810 d5227a230b79d93b2f9b273606fb0f62 489 Gene3D G3DSA:3.40.50.10420 58 136 2.9E-11 T 29-03-2018 SMALA_RS33810 d5227a230b79d93b2f9b273606fb0f62 489 Pfam PF02589 LUD domain 64 291 5.9E-49 T 29-03-2018 IPR003741 LUD domain SMALA_RS33810 d5227a230b79d93b2f9b273606fb0f62 489 SUPERFAMILY SSF100950 129 293 7.95E-36 T 29-03-2018 SMALA_RS33810 d5227a230b79d93b2f9b273606fb0f62 489 SUPERFAMILY SSF100950 58 83 7.95E-36 T 29-03-2018 SMALA_RS33810 d5227a230b79d93b2f9b273606fb0f62 489 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 311 322 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site SMALA_RS33810 d5227a230b79d93b2f9b273606fb0f62 489 SUPERFAMILY SSF54862 289 392 1.05E-14 T 29-03-2018 SMALA_RS33810 d5227a230b79d93b2f9b273606fb0f62 489 Gene3D G3DSA:3.30.70.20 297 319 0.021 T 29-03-2018 SMALA_RS41775 f3b31085acd0b937dc2481b1c3e0a793 121 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 7.6E-10 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS41775 f3b31085acd0b937dc2481b1c3e0a793 121 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 7.6E-10 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS41775 f3b31085acd0b937dc2481b1c3e0a793 121 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 7.6E-10 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS41775 f3b31085acd0b937dc2481b1c3e0a793 121 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS41775 f3b31085acd0b937dc2481b1c3e0a793 121 SMART SM00422 1 69 2.6E-16 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS41775 f3b31085acd0b937dc2481b1c3e0a793 121 SUPERFAMILY SSF46955 2 115 2.05E-26 T 29-03-2018 IPR009061 Putative DNA-binding domain SMALA_RS41775 f3b31085acd0b937dc2481b1c3e0a793 121 Gene3D G3DSA:1.10.1660.10 55 121 4.2E-10 T 29-03-2018 SMALA_RS41775 f3b31085acd0b937dc2481b1c3e0a793 121 Pfam PF13411 MerR HTH family regulatory protein 2 67 2.0E-16 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS41775 f3b31085acd0b937dc2481b1c3e0a793 121 Gene3D G3DSA:1.10.1660.10 1 54 3.2E-19 T 29-03-2018 SMALA_RS38365 cf733243f2d830f1e3483922f48058a8 79 Gene3D G3DSA:1.10.1220.10 1 53 9.9E-6 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 SMALA_RS21230 8cfeac08cc0b0f9f93f1bb828caea581 648 Gene3D G3DSA:3.30.565.10 521 648 1.8E-12 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS21230 8cfeac08cc0b0f9f93f1bb828caea581 648 Gene3D G3DSA:3.30.450.20 76 273 1.3E-14 T 29-03-2018 SMALA_RS21230 8cfeac08cc0b0f9f93f1bb828caea581 648 SUPERFAMILY SSF81606 314 510 2.35E-9 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS21230 8cfeac08cc0b0f9f93f1bb828caea581 648 SUPERFAMILY SSF55874 554 643 1.32E-6 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS21230 8cfeac08cc0b0f9f93f1bb828caea581 648 Gene3D G3DSA:3.60.40.10 274 512 2.4E-41 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS21230 8cfeac08cc0b0f9f93f1bb828caea581 648 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 328 511 1.4E-48 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS21230 8cfeac08cc0b0f9f93f1bb828caea581 648 Pfam PF13581 Histidine kinase-like ATPase domain 535 626 1.0E-6 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS21230 8cfeac08cc0b0f9f93f1bb828caea581 648 SMART SM00331 301 511 1.5E-37 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS36410 1f63af8dc035c020eb2944585355b7a7 226 Gene3D G3DSA:1.20.120.530 79 226 4.7E-28 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS36410 1f63af8dc035c020eb2944585355b7a7 226 Gene3D G3DSA:1.10.10.10 2 78 1.2E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS36410 1f63af8dc035c020eb2944585355b7a7 226 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 36 50 2.5E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS36410 1f63af8dc035c020eb2944585355b7a7 226 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 50 66 2.5E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS36410 1f63af8dc035c020eb2944585355b7a7 226 SUPERFAMILY SSF48008 83 219 1.41E-24 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS36410 1f63af8dc035c020eb2944585355b7a7 226 Pfam PF07729 FCD domain 86 211 1.1E-26 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS36410 1f63af8dc035c020eb2944585355b7a7 226 Pfam PF00392 Bacterial regulatory proteins, gntR family 16 76 2.2E-23 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS36410 1f63af8dc035c020eb2944585355b7a7 226 SMART SM00895 86 212 1.1E-18 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS36410 1f63af8dc035c020eb2944585355b7a7 226 SUPERFAMILY SSF46785 9 102 1.78E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS36410 1f63af8dc035c020eb2944585355b7a7 226 SMART SM00345 18 76 1.5E-23 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS40615 e7ea0da9a6b38791bb5beb1d6588882f 510 ProSitePatterns PS00455 Putative AMP-binding domain signature. 158 169 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS40615 e7ea0da9a6b38791bb5beb1d6588882f 510 Pfam PF13193 AMP-binding enzyme C-terminal domain 412 487 4.0E-22 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS40615 e7ea0da9a6b38791bb5beb1d6588882f 510 Gene3D G3DSA:2.30.38.10 316 396 3.3E-27 T 29-03-2018 SMALA_RS40615 e7ea0da9a6b38791bb5beb1d6588882f 510 Gene3D G3DSA:3.40.50.980 164 315 1.3E-49 T 29-03-2018 SMALA_RS40615 e7ea0da9a6b38791bb5beb1d6588882f 510 Gene3D G3DSA:3.30.300.30 397 500 9.0E-32 T 29-03-2018 SMALA_RS40615 e7ea0da9a6b38791bb5beb1d6588882f 510 Pfam PF00501 AMP-binding enzyme 12 403 1.3E-110 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS40615 e7ea0da9a6b38791bb5beb1d6588882f 510 SUPERFAMILY SSF56801 9 499 9.94E-163 T 29-03-2018 SMALA_RS40615 e7ea0da9a6b38791bb5beb1d6588882f 510 Gene3D G3DSA:3.40.50.980 2 163 3.1E-45 T 29-03-2018 SMALA_RS21240 9d9f928341ed41f4265e2f503fb3c22e 183 SUPERFAMILY SSF46785 27 169 4.12E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS21240 9d9f928341ed41f4265e2f503fb3c22e 183 PRINTS PR00598 Bacterial regulatory protein MarR family signature 95 110 2.2E-8 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS21240 9d9f928341ed41f4265e2f503fb3c22e 183 PRINTS PR00598 Bacterial regulatory protein MarR family signature 78 94 2.2E-8 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS21240 9d9f928341ed41f4265e2f503fb3c22e 183 PRINTS PR00598 Bacterial regulatory protein MarR family signature 144 164 2.2E-8 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS21240 9d9f928341ed41f4265e2f503fb3c22e 183 PRINTS PR00598 Bacterial regulatory protein MarR family signature 114 130 2.2E-8 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS21240 9d9f928341ed41f4265e2f503fb3c22e 183 SMART SM00347 51 154 1.2E-20 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS21240 9d9f928341ed41f4265e2f503fb3c22e 183 Pfam PF12802 MarR family 56 115 3.7E-12 T 29-03-2018 SMALA_RS21240 9d9f928341ed41f4265e2f503fb3c22e 183 ProSitePatterns PS00519 AsnC-type HTH domain signature. 79 105 - T 29-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site SMALA_RS21240 9d9f928341ed41f4265e2f503fb3c22e 183 Gene3D G3DSA:1.10.10.10 6 175 2.1E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS36500 d7647afe278dc070a8aadaf53e8e0dae 455 Gene3D G3DSA:1.20.1250.20 9 232 3.8E-25 T 29-03-2018 SMALA_RS36500 d7647afe278dc070a8aadaf53e8e0dae 455 ProSitePatterns PS00216 Sugar transport proteins signature 1. 301 318 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMALA_RS36500 d7647afe278dc070a8aadaf53e8e0dae 455 Pfam PF00083 Sugar (and other) transporter 24 229 2.8E-28 T 29-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 SMALA_RS36500 d7647afe278dc070a8aadaf53e8e0dae 455 SUPERFAMILY SSF103473 16 432 3.4E-68 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS36500 d7647afe278dc070a8aadaf53e8e0dae 455 Gene3D G3DSA:1.20.1250.20 242 436 5.2E-23 T 29-03-2018 SMALA_RS36500 d7647afe278dc070a8aadaf53e8e0dae 455 Pfam PF07690 Major Facilitator Superfamily 259 439 3.3E-14 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS36500 d7647afe278dc070a8aadaf53e8e0dae 455 ProSitePatterns PS00217 Sugar transport proteins signature 2. 131 156 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMALA_RS07990 77a72a3750318e65a4729c4b806599e8 278 Pfam PF13649 Methyltransferase domain 44 141 5.1E-6 T 29-03-2018 SMALA_RS07990 77a72a3750318e65a4729c4b806599e8 278 Gene3D G3DSA:3.40.50.150 20 174 5.9E-10 T 29-03-2018 SMALA_RS07990 77a72a3750318e65a4729c4b806599e8 278 SUPERFAMILY SSF53335 23 142 8.59E-12 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS31565 04c1ff49fc7dc8c98dd1728620cbf408 563 SUPERFAMILY SSF51735 5 261 7.88E-34 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS31565 04c1ff49fc7dc8c98dd1728620cbf408 563 Gene3D G3DSA:3.40.50.720 4 308 2.3E-33 T 29-03-2018 SMALA_RS31565 04c1ff49fc7dc8c98dd1728620cbf408 563 SUPERFAMILY SSF53474 324 557 1.25E-32 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS31565 04c1ff49fc7dc8c98dd1728620cbf408 563 Pfam PF12697 Alpha/beta hydrolase family 346 552 6.4E-17 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS31565 04c1ff49fc7dc8c98dd1728620cbf408 563 Gene3D G3DSA:3.40.50.1820 389 559 7.8E-17 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS31565 04c1ff49fc7dc8c98dd1728620cbf408 563 Gene3D G3DSA:3.40.50.1820 327 388 3.9E-7 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS31565 04c1ff49fc7dc8c98dd1728620cbf408 563 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 169 7.3E-11 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 SMALA_RS38975 f2cb8ac2b2406b67014f2fffef657765 478 Gene3D G3DSA:1.20.91.10 306 391 3.9E-19 T 29-03-2018 SMALA_RS38975 f2cb8ac2b2406b67014f2fffef657765 478 Pfam PF00999 Sodium/hydrogen exchanger family 67 457 5.9E-58 T 29-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 SMALA_RS13785 4ba9bdec34620366f2faff0ec38a3122 1664 Pfam PF00550 Phosphopantetheine attachment site 1497 1563 1.0E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS13785 4ba9bdec34620366f2faff0ec38a3122 1664 Pfam PF08659 KR domain 1208 1385 3.9E-52 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13785 4ba9bdec34620366f2faff0ec38a3122 1664 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1208 1387 5.7E-49 T 29-03-2018 SMALA_RS13785 4ba9bdec34620366f2faff0ec38a3122 1664 SUPERFAMILY SSF47336 1487 1573 2.09E-22 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS13785 4ba9bdec34620366f2faff0ec38a3122 1664 Gene3D G3DSA:3.40.47.10 28 298 4.0E-89 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13785 4ba9bdec34620366f2faff0ec38a3122 1664 Gene3D G3DSA:3.40.366.10 752 873 1.1E-25 T 29-03-2018 SMALA_RS13785 4ba9bdec34620366f2faff0ec38a3122 1664 Pfam PF00698 Acyl transferase domain 567 882 1.1E-84 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS13785 4ba9bdec34620366f2faff0ec38a3122 1664 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 294 411 2.2E-45 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS13785 4ba9bdec34620366f2faff0ec38a3122 1664 SMART SM00823 Phosphopantetheine attachment site 1495 1567 3.0E-30 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS13785 4ba9bdec34620366f2faff0ec38a3122 1664 SMART SM01294 1496 1563 1.7E-5 T 29-03-2018 SMALA_RS13785 4ba9bdec34620366f2faff0ec38a3122 1664 SUPERFAMILY SSF53901 33 408 1.97E-106 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13785 4ba9bdec34620366f2faff0ec38a3122 1664 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 36 286 2.6E-94 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS13785 4ba9bdec34620366f2faff0ec38a3122 1664 SUPERFAMILY SSF52151 565 693 1.31E-66 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS13785 4ba9bdec34620366f2faff0ec38a3122 1664 SUPERFAMILY SSF52151 759 857 1.31E-66 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS13785 4ba9bdec34620366f2faff0ec38a3122 1664 Gene3D G3DSA:3.40.366.10 564 705 6.0E-44 T 29-03-2018 SMALA_RS13785 4ba9bdec34620366f2faff0ec38a3122 1664 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 568 867 2.0E-120 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS13785 4ba9bdec34620366f2faff0ec38a3122 1664 Pfam PF08990 Erythronolide synthase docking 4 29 5.9E-10 T 29-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 SMALA_RS13785 4ba9bdec34620366f2faff0ec38a3122 1664 Gene3D G3DSA:1.10.1200.10 1474 1567 9.9E-21 T 29-03-2018 SMALA_RS13785 4ba9bdec34620366f2faff0ec38a3122 1664 SUPERFAMILY SSF101173 5 36 9.81E-7 T 29-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 SMALA_RS13785 4ba9bdec34620366f2faff0ec38a3122 1664 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1522 1537 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS13785 4ba9bdec34620366f2faff0ec38a3122 1664 SUPERFAMILY SSF55048 692 758 7.85E-14 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS13785 4ba9bdec34620366f2faff0ec38a3122 1664 SUPERFAMILY SSF51735 978 1195 1.1E-50 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS13785 4ba9bdec34620366f2faff0ec38a3122 1664 Gene3D G3DSA:3.30.70.250 706 751 3.1E-19 T 29-03-2018 SMALA_RS13785 4ba9bdec34620366f2faff0ec38a3122 1664 Gene3D G3DSA:3.40.47.10 301 462 3.5E-64 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS13785 4ba9bdec34620366f2faff0ec38a3122 1664 SUPERFAMILY SSF51735 1207 1439 7.33E-45 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS13785 4ba9bdec34620366f2faff0ec38a3122 1664 SMART SM00825 Beta-ketoacyl synthase 38 464 2.8E-227 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS13785 4ba9bdec34620366f2faff0ec38a3122 1664 Gene3D G3DSA:3.40.50.720 1200 1459 3.3E-49 T 29-03-2018 SMALA_RS13785 4ba9bdec34620366f2faff0ec38a3122 1664 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 199 215 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS13785 4ba9bdec34620366f2faff0ec38a3122 1664 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 414 530 8.5E-19 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS22560 803f42c85c7e1e7c535554d01933c864 115 Pfam PF00237 Ribosomal protein L22p/L17e 5 108 1.1E-36 T 29-03-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 SMALA_RS22560 803f42c85c7e1e7c535554d01933c864 115 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 5 108 5.6E-45 T 29-03-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS22560 803f42c85c7e1e7c535554d01933c864 115 SUPERFAMILY SSF54843 1 112 1.83E-42 T 29-03-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 SMALA_RS22560 803f42c85c7e1e7c535554d01933c864 115 ProSitePatterns PS00464 Ribosomal protein L22 signature. 84 108 - T 29-03-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMALA_RS22560 803f42c85c7e1e7c535554d01933c864 115 Gene3D G3DSA:3.90.470.10 1 115 1.9E-45 T 29-03-2018 SMALA_RS22560 803f42c85c7e1e7c535554d01933c864 115 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 1 111 30.34 T 29-03-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS31775 978fbdf14c19d1de91ec7ed2d3a0a1a0 123 ProSitePatterns PS00234 Gas vesicles protein GVPa signature 1. 24 38 - T 29-03-2018 IPR018493 Gas vesicle protein GvpA, conserved site GO:0005198|GO:0012506 SMALA_RS31775 978fbdf14c19d1de91ec7ed2d3a0a1a0 123 Pfam PF00741 Gas vesicle protein 23 61 3.0E-17 T 29-03-2018 IPR000638 Gas vesicle protein GvpA GO:0005198|GO:0012506 SMALA_RS39975 660377adb1cdfc8b18b99f16a6a150ba 224 Pfam PF13483 Beta-lactamase superfamily domain 2 183 9.0E-23 T 29-03-2018 SMALA_RS39975 660377adb1cdfc8b18b99f16a6a150ba 224 Gene3D G3DSA:3.60.15.10 1 214 3.3E-26 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS39975 660377adb1cdfc8b18b99f16a6a150ba 224 SUPERFAMILY SSF56281 1 190 1.04E-22 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS39975 660377adb1cdfc8b18b99f16a6a150ba 224 SMART SM00849 7 183 0.0019 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS43060 11730d73c0e4496e8d2f934edd579e59 352 SUPERFAMILY SSF52540 61 116 6.21E-10 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS43060 11730d73c0e4496e8d2f934edd579e59 352 SUPERFAMILY SSF52540 151 322 6.21E-10 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS43060 11730d73c0e4496e8d2f934edd579e59 352 Gene3D G3DSA:3.40.50.300 64 300 2.3E-7 T 29-03-2018 SMALA_RS43060 11730d73c0e4496e8d2f934edd579e59 352 Pfam PF05621 Bacterial TniB protein 67 318 5.5E-25 T 29-03-2018 IPR008868 Bacterial TniB SMALA_RS07355 c8a23bbdd561fe1add487636c0416ac5 352 Pfam PF00296 Luciferase-like monooxygenase 1 306 1.2E-72 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS07355 c8a23bbdd561fe1add487636c0416ac5 352 SUPERFAMILY SSF51679 1 344 2.09E-79 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS07355 c8a23bbdd561fe1add487636c0416ac5 352 Gene3D G3DSA:3.20.20.30 1 349 1.4E-80 T 29-03-2018 SMALA_RS35270 d124cf3daf68fbc576167760ee61cfc8 505 Hamap MF_00186 Glycerol kinase [glpK]. 2 502 54.639 T 29-03-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 SMALA_RS35270 d124cf3daf68fbc576167760ee61cfc8 505 Gene3D G3DSA:3.30.420.40 254 504 5.8E-81 T 29-03-2018 SMALA_RS35270 d124cf3daf68fbc576167760ee61cfc8 505 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 4 501 9.6E-221 T 29-03-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 SMALA_RS35270 d124cf3daf68fbc576167760ee61cfc8 505 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 265 455 1.8E-66 T 29-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 SMALA_RS35270 d124cf3daf68fbc576167760ee61cfc8 505 Gene3D G3DSA:3.30.420.40 1 253 4.7E-82 T 29-03-2018 SMALA_RS35270 d124cf3daf68fbc576167760ee61cfc8 505 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 5 256 1.2E-69 T 29-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 SMALA_RS35270 d124cf3daf68fbc576167760ee61cfc8 505 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 134 146 - T 29-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 SMALA_RS35270 d124cf3daf68fbc576167760ee61cfc8 505 SUPERFAMILY SSF53067 4 259 2.89E-82 T 29-03-2018 SMALA_RS35270 d124cf3daf68fbc576167760ee61cfc8 505 SUPERFAMILY SSF53067 259 502 3.39E-85 T 29-03-2018 SMALA_RS35270 d124cf3daf68fbc576167760ee61cfc8 505 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 367 387 - T 29-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 SMALA_RS35270 d124cf3daf68fbc576167760ee61cfc8 505 PIRSF PIRSF000538 3 505 3.2E-158 T 29-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 SMALA_RS12040 3c3e6edc73a9d30f401a81fd80072ed7 421 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 6 253 1.2E-55 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS12040 3c3e6edc73a9d30f401a81fd80072ed7 421 SUPERFAMILY SSF53901 6 258 9.02E-69 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS12040 3c3e6edc73a9d30f401a81fd80072ed7 421 Gene3D G3DSA:3.40.47.10 1 264 3.8E-69 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS12040 3c3e6edc73a9d30f401a81fd80072ed7 421 SUPERFAMILY SSF53901 220 420 7.2E-61 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS12040 3c3e6edc73a9d30f401a81fd80072ed7 421 Gene3D G3DSA:3.40.47.10 266 421 4.9E-42 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS12040 3c3e6edc73a9d30f401a81fd80072ed7 421 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 261 375 2.7E-29 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS12040 3c3e6edc73a9d30f401a81fd80072ed7 421 PIRSF PIRSF000447 3 421 1.1E-141 T 29-03-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 SMALA_RS12040 3c3e6edc73a9d30f401a81fd80072ed7 421 SMART SM00825 Beta-ketoacyl synthase 8 412 4.5E-13 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS29970 bce58ffddc5aae87eee0fbe41b1fe03e 288 Gene3D G3DSA:1.10.10.10 133 245 5.5E-34 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS29970 bce58ffddc5aae87eee0fbe41b1fe03e 288 SMART SM00862 163 238 2.5E-29 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS29970 bce58ffddc5aae87eee0fbe41b1fe03e 288 Gene3D G3DSA:3.40.50.2300 1 132 7.3E-41 T 29-03-2018 SMALA_RS29970 bce58ffddc5aae87eee0fbe41b1fe03e 288 SUPERFAMILY SSF46894 141 239 2.04E-28 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS29970 bce58ffddc5aae87eee0fbe41b1fe03e 288 Pfam PF00486 Transcriptional regulatory protein, C terminal 163 238 3.6E-27 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS29970 bce58ffddc5aae87eee0fbe41b1fe03e 288 SUPERFAMILY SSF52172 4 127 8.4E-45 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS29970 bce58ffddc5aae87eee0fbe41b1fe03e 288 SMART SM00448 8 118 1.3E-47 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS29970 bce58ffddc5aae87eee0fbe41b1fe03e 288 Pfam PF00072 Response regulator receiver domain 10 118 3.6E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS32150 fcbfff83e0a065cc07e652414e112c68 265 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 18 191 1.8E-27 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain SMALA_RS32150 fcbfff83e0a065cc07e652414e112c68 265 Gene3D G3DSA:3.40.50.1110 2 203 1.6E-30 T 29-03-2018 SMALA_RS32150 fcbfff83e0a065cc07e652414e112c68 265 SUPERFAMILY SSF52266 15 199 5.5E-36 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain SMALA_RS38385 0458ba16b872b08042f95d72f983b61c 394 Gene3D G3DSA:2.130.10.10 258 393 2.0E-27 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMALA_RS38385 0458ba16b872b08042f95d72f983b61c 394 Gene3D G3DSA:2.130.10.10 84 161 1.1E-10 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMALA_RS38385 0458ba16b872b08042f95d72f983b61c 394 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 85 120 4.9E-10 T 29-03-2018 IPR011964 YVTN beta-propeller repeat SMALA_RS38385 0458ba16b872b08042f95d72f983b61c 394 SUPERFAMILY SSF50974 83 380 7.59E-64 T 29-03-2018 IPR011045 Nitrous oxide reductase, N-terminal Reactome: R-HSA-114608 SMALA_RS38385 0458ba16b872b08042f95d72f983b61c 394 Gene3D G3DSA:2.130.10.10 162 257 4.6E-12 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMALA_RS38385 0458ba16b872b08042f95d72f983b61c 394 Pfam PF10282 Lactonase, 7-bladed beta-propeller 162 365 1.7E-8 T 29-03-2018 IPR019405 Lactonase, 7-bladed beta propeller SMALA_RS12610 6fac1b4b6014a3e425aa5272edb830c1 398 Gene3D G3DSA:1.25.40.10 298 382 0.0044 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS12610 6fac1b4b6014a3e425aa5272edb830c1 398 SMART SM00530 12 67 2.2E-9 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS12610 6fac1b4b6014a3e425aa5272edb830c1 398 Pfam PF13560 Helix-turn-helix domain 10 66 8.0E-10 T 29-03-2018 SMALA_RS12610 6fac1b4b6014a3e425aa5272edb830c1 398 SUPERFAMILY SSF47413 5 70 4.29E-13 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS12610 6fac1b4b6014a3e425aa5272edb830c1 398 Gene3D G3DSA:1.25.40.10 136 287 0.073 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS12610 6fac1b4b6014a3e425aa5272edb830c1 398 Gene3D G3DSA:1.10.260.40 1 82 5.5E-16 T 29-03-2018 SMALA_RS17895 1a03157433a57c958ed9edf607e5b0a9 606 Pfam PF00149 Calcineurin-like phosphoesterase 58 314 2.6E-4 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 SMALA_RS17895 1a03157433a57c958ed9edf607e5b0a9 606 Gene3D G3DSA:3.90.780.10 409 605 1.4E-51 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 SMALA_RS17895 1a03157433a57c958ed9edf607e5b0a9 606 Gene3D G3DSA:3.60.21.10 41 408 3.5E-75 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SMALA_RS17895 1a03157433a57c958ed9edf607e5b0a9 606 SUPERFAMILY SSF55816 396 605 5.23E-47 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 SMALA_RS17895 1a03157433a57c958ed9edf607e5b0a9 606 Pfam PF02872 5'-nucleotidase, C-terminal domain 398 566 2.2E-38 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 SMALA_RS17895 1a03157433a57c958ed9edf607e5b0a9 606 PRINTS PR01607 Apyrase family signature 463 486 6.6E-19 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 SMALA_RS17895 1a03157433a57c958ed9edf607e5b0a9 606 PRINTS PR01607 Apyrase family signature 51 69 6.6E-19 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 SMALA_RS17895 1a03157433a57c958ed9edf607e5b0a9 606 PRINTS PR01607 Apyrase family signature 297 320 6.6E-19 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 SMALA_RS17895 1a03157433a57c958ed9edf607e5b0a9 606 PRINTS PR01607 Apyrase family signature 539 558 6.6E-19 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 SMALA_RS17895 1a03157433a57c958ed9edf607e5b0a9 606 SUPERFAMILY SSF56300 47 391 2.2E-66 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SMALA_RS26000 9948d35d1609d07f0cea508de8c2100b 1265 Gene3D G3DSA:3.40.50.300 19 349 6.9E-49 T 29-03-2018 SMALA_RS26000 9948d35d1609d07f0cea508de8c2100b 1265 Pfam PF12705 PD-(D/E)XK nuclease superfamily 1042 1189 1.7E-7 T 29-03-2018 SMALA_RS26000 9948d35d1609d07f0cea508de8c2100b 1265 Pfam PF00580 UvrD/REP helicase N-terminal domain 30 336 1.1E-49 T 29-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 SMALA_RS26000 9948d35d1609d07f0cea508de8c2100b 1265 Gene3D G3DSA:1.10.486.10 458 657 5.2E-32 T 29-03-2018 SMALA_RS26000 9948d35d1609d07f0cea508de8c2100b 1265 Gene3D G3DSA:3.90.320.10 980 1189 4.1E-14 T 29-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 SMALA_RS26000 9948d35d1609d07f0cea508de8c2100b 1265 Gene3D G3DSA:3.40.50.300 350 457 2.7E-12 T 29-03-2018 SMALA_RS26000 9948d35d1609d07f0cea508de8c2100b 1265 Pfam PF13361 UvrD-like helicase C-terminal domain 665 764 1.4E-10 T 29-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 SMALA_RS26000 9948d35d1609d07f0cea508de8c2100b 1265 Pfam PF13361 UvrD-like helicase C-terminal domain 348 500 4.6E-12 T 29-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 SMALA_RS26000 9948d35d1609d07f0cea508de8c2100b 1265 SUPERFAMILY SSF52540 746 792 3.26E-111 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS26000 9948d35d1609d07f0cea508de8c2100b 1265 SUPERFAMILY SSF52540 27 499 3.26E-111 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS26000 9948d35d1609d07f0cea508de8c2100b 1265 SUPERFAMILY SSF52540 547 705 3.26E-111 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS09945 566657d79b7bd3232d816c366439a7a2 322 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 141 153 - T 29-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 SMALA_RS09945 566657d79b7bd3232d816c366439a7a2 322 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 14 257 2.9E-64 T 29-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 SMALA_RS09945 566657d79b7bd3232d816c366439a7a2 322 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 9 263 15.709 T 29-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 SMALA_RS09945 566657d79b7bd3232d816c366439a7a2 322 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 10 258 1.9E-42 T 29-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 SMALA_RS26560 a83997f565313c0d9166964f92b0b49b 1281 SUPERFAMILY SSF52518 463 870 2.58E-86 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold SMALA_RS26560 a83997f565313c0d9166964f92b0b49b 1281 Pfam PF16078 2-oxoglutarate dehydrogenase N-terminus 26 62 2.7E-11 T 29-03-2018 IPR032106 2-oxoglutarate dehydrogenase E1 component, N-terminal domain KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 SMALA_RS26560 a83997f565313c0d9166964f92b0b49b 1281 Pfam PF02779 Transketolase, pyrimidine binding domain 932 1125 3.1E-58 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain SMALA_RS26560 a83997f565313c0d9166964f92b0b49b 1281 Pfam PF16870 2-oxoglutarate dehydrogenase C-terminal 1131 1279 2.4E-44 T 29-03-2018 IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 SMALA_RS26560 a83997f565313c0d9166964f92b0b49b 1281 SMART SM00861 933 1126 2.2E-53 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain SMALA_RS26560 a83997f565313c0d9166964f92b0b49b 1281 SUPERFAMILY SSF52777 155 395 6.67E-55 T 29-03-2018 SMALA_RS26560 a83997f565313c0d9166964f92b0b49b 1281 SUPERFAMILY SSF52518 922 1132 9.25E-47 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold SMALA_RS26560 a83997f565313c0d9166964f92b0b49b 1281 Gene3D G3DSA:1.10.287.1150 426 508 1.6E-23 T 29-03-2018 SMALA_RS26560 a83997f565313c0d9166964f92b0b49b 1281 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 165 395 1.1E-50 T 29-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 SMALA_RS26560 a83997f565313c0d9166964f92b0b49b 1281 Gene3D G3DSA:3.40.50.970 509 869 6.4E-93 T 29-03-2018 SMALA_RS26560 a83997f565313c0d9166964f92b0b49b 1281 Gene3D G3DSA:3.40.50.970 929 1139 1.1E-53 T 29-03-2018 SMALA_RS26560 a83997f565313c0d9166964f92b0b49b 1281 Gene3D G3DSA:3.30.559.10 146 400 5.2E-52 T 29-03-2018 SMALA_RS26560 a83997f565313c0d9166964f92b0b49b 1281 Pfam PF00676 Dehydrogenase E1 component 548 868 1.9E-54 T 29-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 SMALA_RS26560 a83997f565313c0d9166964f92b0b49b 1281 TIGRFAM TIGR00239 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component 425 1278 0.0 T 29-03-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 SMALA_RS27615 3e4f9ff5a7ac41f94560feab521f452c 583 Pfam PF08241 Methyltransferase domain 374 472 5.9E-20 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 SMALA_RS27615 3e4f9ff5a7ac41f94560feab521f452c 583 Gene3D G3DSA:1.10.287.840 492 576 1.0E-28 T 29-03-2018 IPR023143 Mycolic acid cyclopropane synthase-like domain SMALA_RS27615 3e4f9ff5a7ac41f94560feab521f452c 583 Gene3D G3DSA:1.10.287.840 320 365 1.4E-14 T 29-03-2018 IPR023143 Mycolic acid cyclopropane synthase-like domain SMALA_RS27615 3e4f9ff5a7ac41f94560feab521f452c 583 SUPERFAMILY SSF53335 314 583 1.17E-50 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS27615 3e4f9ff5a7ac41f94560feab521f452c 583 Gene3D G3DSA:3.40.50.150 45 311 4.5E-24 T 29-03-2018 SMALA_RS27615 3e4f9ff5a7ac41f94560feab521f452c 583 Pfam PF13649 Methyltransferase domain 89 187 5.1E-13 T 29-03-2018 SMALA_RS27615 3e4f9ff5a7ac41f94560feab521f452c 583 SUPERFAMILY SSF53335 57 289 7.0E-36 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS27615 3e4f9ff5a7ac41f94560feab521f452c 583 Gene3D G3DSA:3.40.50.150 366 491 5.1E-17 T 29-03-2018 SMALA_RS21540 6c1285491b41a350f6457f6dfa8494e4 245 Gene3D G3DSA:1.10.10.10 135 244 2.6E-34 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS21540 6c1285491b41a350f6457f6dfa8494e4 245 SUPERFAMILY SSF46894 140 237 1.79E-31 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS21540 6c1285491b41a350f6457f6dfa8494e4 245 SMART SM00448 10 121 3.5E-42 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS21540 6c1285491b41a350f6457f6dfa8494e4 245 Pfam PF00072 Response regulator receiver domain 12 122 1.0E-29 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS21540 6c1285491b41a350f6457f6dfa8494e4 245 Gene3D G3DSA:3.40.50.2300 2 134 3.1E-39 T 29-03-2018 SMALA_RS21540 6c1285491b41a350f6457f6dfa8494e4 245 Pfam PF00486 Transcriptional regulatory protein, C terminal 162 237 2.0E-26 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS21540 6c1285491b41a350f6457f6dfa8494e4 245 SUPERFAMILY SSF52172 7 133 2.7E-43 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS21540 6c1285491b41a350f6457f6dfa8494e4 245 SMART SM00862 162 237 2.5E-27 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS18030 cc4855e1bc000d7b76467b906cb88b20 237 SUPERFAMILY SSF52172 1 135 4.7E-35 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS18030 cc4855e1bc000d7b76467b906cb88b20 237 Pfam PF00196 Bacterial regulatory proteins, luxR family 160 215 8.9E-19 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS18030 cc4855e1bc000d7b76467b906cb88b20 237 Gene3D G3DSA:3.40.50.2300 2 127 5.9E-39 T 29-03-2018 SMALA_RS18030 cc4855e1bc000d7b76467b906cb88b20 237 SUPERFAMILY SSF46894 154 221 1.39E-22 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS18030 cc4855e1bc000d7b76467b906cb88b20 237 Pfam PF00072 Response regulator receiver domain 5 117 7.5E-28 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS18030 cc4855e1bc000d7b76467b906cb88b20 237 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 191 203 3.3E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS18030 cc4855e1bc000d7b76467b906cb88b20 237 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 161 175 3.3E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS18030 cc4855e1bc000d7b76467b906cb88b20 237 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 175 191 3.3E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS18030 cc4855e1bc000d7b76467b906cb88b20 237 SMART SM00448 3 116 6.1E-31 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS18030 cc4855e1bc000d7b76467b906cb88b20 237 ProSitePatterns PS00622 LuxR-type HTH domain signature. 175 202 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS18030 cc4855e1bc000d7b76467b906cb88b20 237 Gene3D G3DSA:1.10.10.10 128 225 6.1E-32 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS18030 cc4855e1bc000d7b76467b906cb88b20 237 SMART SM00421 158 215 5.0E-25 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS28630 18e710b426930d09106d7ccf42a6f990 726 Gene3D G3DSA:3.30.200.20 11 95 3.8E-10 T 29-03-2018 SMALA_RS28630 18e710b426930d09106d7ccf42a6f990 726 Pfam PF13360 PQQ-like domain 389 591 3.6E-9 T 29-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat SMALA_RS28630 18e710b426930d09106d7ccf42a6f990 726 SMART SM00220 16 264 2.5E-40 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMALA_RS28630 18e710b426930d09106d7ccf42a6f990 726 SUPERFAMILY SSF50998 335 696 5.59E-14 T 29-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily SMALA_RS28630 18e710b426930d09106d7ccf42a6f990 726 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 22 44 - T 29-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 SMALA_RS28630 18e710b426930d09106d7ccf42a6f990 726 Gene3D G3DSA:1.10.510.10 96 265 1.1E-40 T 29-03-2018 SMALA_RS28630 18e710b426930d09106d7ccf42a6f990 726 SMART SM00564 564 593 260.0 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMALA_RS28630 18e710b426930d09106d7ccf42a6f990 726 SMART SM00564 474 508 300.0 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMALA_RS28630 18e710b426930d09106d7ccf42a6f990 726 SMART SM00564 611 643 0.73 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMALA_RS28630 18e710b426930d09106d7ccf42a6f990 726 Gene3D G3DSA:2.130.10.10 287 478 0.23 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMALA_RS28630 18e710b426930d09106d7ccf42a6f990 726 SUPERFAMILY SSF56112 13 261 1.15E-58 T 29-03-2018 IPR011009 Protein kinase-like domain SMALA_RS28630 18e710b426930d09106d7ccf42a6f990 726 Gene3D G3DSA:2.140.10.10 479 603 9.3E-11 T 29-03-2018 SMALA_RS28630 18e710b426930d09106d7ccf42a6f990 726 Gene3D G3DSA:2.140.10.10 604 724 8.1E-8 T 29-03-2018 SMALA_RS28630 18e710b426930d09106d7ccf42a6f990 726 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 134 146 - T 29-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMALA_RS28630 18e710b426930d09106d7ccf42a6f990 726 Pfam PF00069 Protein kinase domain 16 259 1.2E-33 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMALA_RS19690 2620855ef61b5845457cd5a6ec8f4a2b 169 SUPERFAMILY SSF82708 124 168 9.22E-11 T 29-03-2018 IPR001374 R3H domain GO:0003676 SMALA_RS19690 2620855ef61b5845457cd5a6ec8f4a2b 169 Gene3D G3DSA:3.30.1370.50 102 169 4.0E-19 T 29-03-2018 IPR001374 R3H domain GO:0003676 SMALA_RS19690 2620855ef61b5845457cd5a6ec8f4a2b 169 Gene3D G3DSA:3.30.300.20 19 100 1.3E-20 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta SMALA_RS19690 2620855ef61b5845457cd5a6ec8f4a2b 169 Pfam PF01424 R3H domain 111 166 5.1E-15 T 29-03-2018 IPR001374 R3H domain GO:0003676 SMALA_RS19690 2620855ef61b5845457cd5a6ec8f4a2b 169 SMART SM00393 91 169 3.9E-25 T 29-03-2018 IPR001374 R3H domain GO:0003676 SMALA_RS17910 729ea932bc0aa5a7f85214d78a3bfa10 278 SUPERFAMILY SSF52096 5 248 9.72E-56 T 29-03-2018 IPR029045 ClpP/crotonase-like domain SMALA_RS17910 729ea932bc0aa5a7f85214d78a3bfa10 278 Gene3D G3DSA:3.90.226.10 1 275 6.8E-55 T 29-03-2018 SMALA_RS17910 729ea932bc0aa5a7f85214d78a3bfa10 278 Pfam PF00378 Enoyl-CoA hydratase/isomerase 14 221 1.4E-38 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 SMALA_RS16790 3b098ec328baf4ed4ac24b64b6998f20 255 Pfam PF13714 Phosphoenolpyruvate phosphomutase 13 250 2.2E-64 T 29-03-2018 SMALA_RS16790 3b098ec328baf4ed4ac24b64b6998f20 255 Gene3D G3DSA:3.20.20.60 4 253 6.2E-55 T 29-03-2018 SMALA_RS16790 3b098ec328baf4ed4ac24b64b6998f20 255 SUPERFAMILY SSF51621 13 251 4.13E-49 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SMALA_RS29705 8ca90c87ce16a64ea2cabc517b448b6c 509 Gene3D G3DSA:3.65.10.10 95 294 4.7E-25 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 SMALA_RS29705 8ca90c87ce16a64ea2cabc517b448b6c 509 Pfam PF01381 Helix-turn-helix 13 63 3.3E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS29705 8ca90c87ce16a64ea2cabc517b448b6c 509 Gene3D G3DSA:1.10.260.40 35 94 6.4E-4 T 29-03-2018 SMALA_RS29705 8ca90c87ce16a64ea2cabc517b448b6c 509 Gene3D G3DSA:3.65.10.10 295 508 2.3E-34 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 SMALA_RS29705 8ca90c87ce16a64ea2cabc517b448b6c 509 SMART SM00530 12 67 1.2E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS29705 8ca90c87ce16a64ea2cabc517b448b6c 509 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 79 496 8.5E-42 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 SMALA_RS29705 8ca90c87ce16a64ea2cabc517b448b6c 509 SUPERFAMILY SSF55205 74 506 6.05E-95 T 29-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 SMALA_RS29705 8ca90c87ce16a64ea2cabc517b448b6c 509 SUPERFAMILY SSF47413 4 65 7.78E-16 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS29705 8ca90c87ce16a64ea2cabc517b448b6c 509 Gene3D G3DSA:1.10.10.60 8 34 2.7E-13 T 29-03-2018 SMALA_RS07230 762caa296d2bd76b8b9a544ebcf911df 453 TIGRFAM TIGR03686 pupylate_PafA: Pup--protein ligase 3 453 8.6E-230 T 29-03-2018 IPR022279 Pup--protein ligase GO:0010498|GO:0016879|GO:0019941 SMALA_RS07230 762caa296d2bd76b8b9a544ebcf911df 453 Pfam PF03136 Pup-ligase protein 4 423 9.3E-156 T 29-03-2018 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 SMALA_RS07230 762caa296d2bd76b8b9a544ebcf911df 453 Hamap MF_02111 Pup--protein ligase [pafA]. 1 453 50.024 T 29-03-2018 IPR022279 Pup--protein ligase GO:0010498|GO:0016879|GO:0019941 SMALA_RS07230 762caa296d2bd76b8b9a544ebcf911df 453 PIRSF PIRSF018077 1 453 1.2E-179 T 29-03-2018 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 SMALA_RS14265 30bc24e0f8876675b1ebbd0b96fa9f88 256 Pfam PF05988 Bacterial protein of unknown function (DUF899) 17 219 3.4E-61 T 29-03-2018 IPR010296 Protein of unknown function DUF899, thioredoxin-like SMALA_RS14265 30bc24e0f8876675b1ebbd0b96fa9f88 256 Gene3D G3DSA:3.40.30.10 29 200 8.7E-8 T 29-03-2018 SMALA_RS05370 c5ed689ec04a9366639b13a26218e1bf 581 Gene3D G3DSA:3.30.1180.20 183 333 6.0E-42 T 29-03-2018 SMALA_RS05370 c5ed689ec04a9366639b13a26218e1bf 581 SUPERFAMILY SSF82549 11 330 1.18E-100 T 29-03-2018 SMALA_RS05370 c5ed689ec04a9366639b13a26218e1bf 581 Pfam PF02734 DAK2 domain 396 570 1.8E-43 T 29-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 SMALA_RS05370 c5ed689ec04a9366639b13a26218e1bf 581 Gene3D G3DSA:3.40.50.10440 11 182 1.8E-52 T 29-03-2018 SMALA_RS05370 c5ed689ec04a9366639b13a26218e1bf 581 SUPERFAMILY SSF101473 370 570 3.4E-42 T 29-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 SMALA_RS05370 c5ed689ec04a9366639b13a26218e1bf 581 SMART SM01120 395 571 3.0E-50 T 29-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 SMALA_RS05370 c5ed689ec04a9366639b13a26218e1bf 581 Pfam PF02733 Dak1 domain 18 328 7.1E-105 T 29-03-2018 IPR004006 DhaK domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 SMALA_RS39540 750c67476ab910710a57922d975d8d29 70 Pfam PF03621 MbtH-like protein 2 53 8.8E-29 T 29-03-2018 IPR005153 MbtH-like protein SMALA_RS39540 750c67476ab910710a57922d975d8d29 70 SMART SM00923 4 54 9.2E-32 T 29-03-2018 IPR005153 MbtH-like protein SMALA_RS39540 750c67476ab910710a57922d975d8d29 70 Gene3D G3DSA:3.90.820.10 3 69 2.3E-35 T 29-03-2018 SMALA_RS39540 750c67476ab910710a57922d975d8d29 70 SUPERFAMILY SSF160582 3 67 2.88E-30 T 29-03-2018 SMALA_RS07225 25c0bffcada744177131a733a4b09f22 331 SUPERFAMILY SSF54534 223 330 1.49E-32 T 29-03-2018 SMALA_RS07225 25c0bffcada744177131a733a4b09f22 331 SUPERFAMILY SSF54534 56 184 1.02E-28 T 29-03-2018 SMALA_RS07225 25c0bffcada744177131a733a4b09f22 331 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 240 328 7.4E-20 T 29-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain SMALA_RS07225 25c0bffcada744177131a733a4b09f22 331 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 93 183 2.0E-20 T 29-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain SMALA_RS07225 25c0bffcada744177131a733a4b09f22 331 Gene3D G3DSA:3.10.50.40 22 190 5.8E-28 T 29-03-2018 SMALA_RS07225 25c0bffcada744177131a733a4b09f22 331 Gene3D G3DSA:3.10.50.40 191 331 2.3E-31 T 29-03-2018 SMALA_RS20570 ddea430e64a99c1f0c2b6a144bf76212 335 Gene3D G3DSA:3.40.190.10 184 270 8.8E-4 T 29-03-2018 SMALA_RS20570 ddea430e64a99c1f0c2b6a144bf76212 335 Gene3D G3DSA:3.40.190.10 100 183 2.2E-7 T 29-03-2018 SMALA_RS20570 ddea430e64a99c1f0c2b6a144bf76212 335 Gene3D G3DSA:1.10.10.10 5 92 1.1E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS20570 ddea430e64a99c1f0c2b6a144bf76212 335 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 27 38 2.9E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS20570 ddea430e64a99c1f0c2b6a144bf76212 335 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 38 48 2.9E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS20570 ddea430e64a99c1f0c2b6a144bf76212 335 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 48 59 2.9E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS20570 ddea430e64a99c1f0c2b6a144bf76212 335 SUPERFAMILY SSF46785 10 89 3.33E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS20570 ddea430e64a99c1f0c2b6a144bf76212 335 SUPERFAMILY SSF53850 114 307 2.17E-14 T 29-03-2018 SMALA_RS20570 ddea430e64a99c1f0c2b6a144bf76212 335 Pfam PF03466 LysR substrate binding domain 115 283 1.1E-12 T 29-03-2018 IPR005119 LysR, substrate-binding SMALA_RS20570 ddea430e64a99c1f0c2b6a144bf76212 335 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 12 70 3.5E-17 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS09670 953ff56ea7fb8bd51ebc716cd94c0665 225 Gene3D G3DSA:3.30.160.70 13 134 4.4E-19 T 29-03-2018 SMALA_RS09670 953ff56ea7fb8bd51ebc716cd94c0665 225 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 139 217 4.9E-26 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 SMALA_RS09670 953ff56ea7fb8bd51ebc716cd94c0665 225 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 28 132 1.9E-4 T 29-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 SMALA_RS09670 953ff56ea7fb8bd51ebc716cd94c0665 225 Gene3D G3DSA:1.10.10.10 135 223 2.4E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS09670 953ff56ea7fb8bd51ebc716cd94c0665 225 SUPERFAMILY SSF46767 139 219 8.5E-24 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 SMALA_RS09670 953ff56ea7fb8bd51ebc716cd94c0665 225 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 139 219 1.0E-25 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 SMALA_RS09670 953ff56ea7fb8bd51ebc716cd94c0665 225 SUPERFAMILY SSF53155 28 72 1.29E-5 T 29-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 SMALA_RS09670 953ff56ea7fb8bd51ebc716cd94c0665 225 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 30 218 36.994 T 29-03-2018 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 SMALA_RS02005 857bef98e472009585ce99811179cb05 231 Pfam PF01965 DJ-1/PfpI family 30 228 4.8E-16 T 29-03-2018 IPR002818 DJ-1/PfpI SMALA_RS02005 857bef98e472009585ce99811179cb05 231 SUPERFAMILY SSF52317 2 230 3.06E-62 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS02005 857bef98e472009585ce99811179cb05 231 Gene3D G3DSA:3.40.50.880 1 231 1.4E-55 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS21715 2f93c5ec8d05ce7d86fe703d4f443691 109 Gene3D G3DSA:2.30.30.410 3 105 1.9E-9 T 29-03-2018 SMALA_RS11650 7d8e4dc02edfdd8243d4c27c12071925 216 Gene3D G3DSA:1.10.150.240 22 79 8.8E-18 T 29-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 SMALA_RS11650 7d8e4dc02edfdd8243d4c27c12071925 216 SUPERFAMILY SSF56784 6 200 7.6E-42 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS11650 7d8e4dc02edfdd8243d4c27c12071925 216 Pfam PF13419 Haloacid dehalogenase-like hydrolase 9 181 3.9E-20 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS11650 7d8e4dc02edfdd8243d4c27c12071925 216 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 8 181 4.4E-17 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMALA_RS11650 7d8e4dc02edfdd8243d4c27c12071925 216 ProSitePatterns PS01228 Hypothetical cof family signature 1. 7 18 - T 29-03-2018 SMALA_RS11650 7d8e4dc02edfdd8243d4c27c12071925 216 Gene3D G3DSA:3.40.50.1000 80 214 1.9E-23 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS04160 aabe881a13ab0531c500acac6162abcf 188 Gene3D G3DSA:3.40.630.30 13 185 9.8E-24 T 29-03-2018 SMALA_RS04160 aabe881a13ab0531c500acac6162abcf 188 Pfam PF13302 Acetyltransferase (GNAT) domain 18 157 5.4E-16 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SMALA_RS04160 aabe881a13ab0531c500acac6162abcf 188 SUPERFAMILY SSF55729 16 181 6.38E-32 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS24255 daa2a69fe2958ab7c15f5623b6bb879f 556 Gene3D G3DSA:3.10.105.10 302 524 9.4E-46 T 29-03-2018 SMALA_RS24255 daa2a69fe2958ab7c15f5623b6bb879f 556 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 109 472 1.5E-68 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain SMALA_RS24255 daa2a69fe2958ab7c15f5623b6bb879f 556 PIRSF PIRSF002741 24 553 9.3E-84 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 SMALA_RS24255 daa2a69fe2958ab7c15f5623b6bb879f 556 Gene3D G3DSA:3.90.76.10 98 259 4.9E-32 T 29-03-2018 SMALA_RS24255 daa2a69fe2958ab7c15f5623b6bb879f 556 SUPERFAMILY SSF53850 63 550 3.08E-110 T 29-03-2018 SMALA_RS35015 999c8959c66e2ee384d739f5933177de 258 Pfam PF08220 DeoR-like helix-turn-helix domain 9 60 8.4E-14 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMALA_RS35015 999c8959c66e2ee384d739f5933177de 258 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 41 59 6.1E-7 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMALA_RS35015 999c8959c66e2ee384d739f5933177de 258 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 27 41 6.1E-7 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMALA_RS35015 999c8959c66e2ee384d739f5933177de 258 Pfam PF00455 DeoR C terminal sensor domain 79 234 3.1E-40 T 29-03-2018 IPR014036 DeoR C-terminal sensor domain SMALA_RS35015 999c8959c66e2ee384d739f5933177de 258 SMART SM00420 9 61 1.6E-11 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMALA_RS35015 999c8959c66e2ee384d739f5933177de 258 Gene3D G3DSA:1.10.10.10 5 72 5.2E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS35015 999c8959c66e2ee384d739f5933177de 258 SMART SM01134 75 236 5.2E-54 T 29-03-2018 SMALA_RS35015 999c8959c66e2ee384d739f5933177de 258 SUPERFAMILY SSF100950 78 238 5.02E-26 T 29-03-2018 SMALA_RS35015 999c8959c66e2ee384d739f5933177de 258 Gene3D G3DSA:3.40.50.1360 73 256 1.0E-35 T 29-03-2018 SMALA_RS35015 999c8959c66e2ee384d739f5933177de 258 SUPERFAMILY SSF46785 8 62 3.7E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS02100 5182a8b2e2c46c6683b6ca57506586a0 229 Gene3D G3DSA:3.40.50.80 108 228 2.9E-25 T 29-03-2018 SMALA_RS02100 5182a8b2e2c46c6683b6ca57506586a0 229 SUPERFAMILY SSF63380 13 108 9.21E-11 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 SMALA_RS02100 5182a8b2e2c46c6683b6ca57506586a0 229 Pfam PF08021 Siderophore-interacting FAD-binding domain 58 107 5.2E-5 T 29-03-2018 IPR013113 FAD-binding 9, siderophore-interacting SMALA_RS02100 5182a8b2e2c46c6683b6ca57506586a0 229 Pfam PF04954 Siderophore-interacting protein 114 224 2.6E-26 T 29-03-2018 IPR007037 Siderophore-interacting protein SMALA_RS02100 5182a8b2e2c46c6683b6ca57506586a0 229 Gene3D G3DSA:2.40.30.10 11 107 1.6E-15 T 29-03-2018 SMALA_RS04575 efc09701169ad8be2f4ed0a6910425aa 332 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 6 320 5.9E-103 T 29-03-2018 IPR019949 Luciferase family oxidoreductase, group 1 SMALA_RS04575 efc09701169ad8be2f4ed0a6910425aa 332 SUPERFAMILY SSF51679 6 321 1.31E-63 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS04575 efc09701169ad8be2f4ed0a6910425aa 332 Pfam PF00296 Luciferase-like monooxygenase 18 297 6.8E-31 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS04575 efc09701169ad8be2f4ed0a6910425aa 332 Gene3D G3DSA:3.20.20.30 9 323 1.8E-65 T 29-03-2018 SMALA_RS25700 3fadbc07e591a292cfa05f173e861e75 294 Pfam PF02585 GlcNAc-PI de-N-acetylase 10 160 2.1E-24 T 29-03-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 SMALA_RS25700 3fadbc07e591a292cfa05f173e861e75 294 Hamap MF_01696 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase [mshB]. 9 292 42.242 T 29-03-2018 IPR017810 Mycothiol biosynthesis protein, MshB GO:0035595 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 SMALA_RS25700 3fadbc07e591a292cfa05f173e861e75 294 SUPERFAMILY SSF102588 7 291 1.44E-69 T 29-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 SMALA_RS25700 3fadbc07e591a292cfa05f173e861e75 294 TIGRFAM TIGR03445 mycothiol_MshB: N-acetyl-1-D-myo-inositol-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase 10 292 4.9E-127 T 29-03-2018 IPR017810 Mycothiol biosynthesis protein, MshB GO:0035595 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 SMALA_RS25700 3fadbc07e591a292cfa05f173e861e75 294 Gene3D G3DSA:3.40.50.10320 4 294 7.8E-80 T 29-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 SMALA_RS05090 d9019af4b207f70b37354b9d5f823b51 500 Gene3D G3DSA:3.30.465.10 135 277 3.6E-25 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SMALA_RS05090 d9019af4b207f70b37354b9d5f823b51 500 Pfam PF08031 Berberine and berberine like 452 496 1.9E-19 T 29-03-2018 IPR012951 Berberine/berberine-like GO:0016491|GO:0050660|GO:0055114 SMALA_RS05090 d9019af4b207f70b37354b9d5f823b51 500 Pfam PF01565 FAD binding domain 81 208 6.0E-24 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 SMALA_RS05090 d9019af4b207f70b37354b9d5f823b51 500 ProSitePatterns PS00862 Oxygen oxidoreductases covalent FAD-binding site. 81 114 - T 29-03-2018 IPR006093 Oxygen oxidoreductase covalent FAD-binding site GO:0016491|GO:0055114 SMALA_RS05090 d9019af4b207f70b37354b9d5f823b51 500 Gene3D G3DSA:3.30.43.10 56 133 6.0E-23 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 SMALA_RS05090 d9019af4b207f70b37354b9d5f823b51 500 SUPERFAMILY SSF56176 54 251 4.11E-43 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SMALA_RS41075 6ae39e79073e226ca123968c44d3e971 409 SUPERFAMILY SSF54373 227 337 7.06E-11 T 29-03-2018 SMALA_RS41075 6ae39e79073e226ca123968c44d3e971 409 Gene3D G3DSA:3.40.50.20 7 62 1.0E-4 T 29-03-2018 SMALA_RS41075 6ae39e79073e226ca123968c44d3e971 409 Gene3D G3DSA:3.30.9.10 75 337 9.8E-28 T 29-03-2018 SMALA_RS41075 6ae39e79073e226ca123968c44d3e971 409 Pfam PF01266 FAD dependent oxidoreductase 18 376 1.8E-41 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 SMALA_RS41075 6ae39e79073e226ca123968c44d3e971 409 SUPERFAMILY SSF51905 17 231 1.81E-36 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS41075 6ae39e79073e226ca123968c44d3e971 409 SUPERFAMILY SSF51905 337 399 1.81E-36 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS28765 c44a151b0ec84b625ecda48ab5b92759 160 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 38 54 1.1E-11 T 29-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 SMALA_RS28765 c44a151b0ec84b625ecda48ab5b92759 160 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 62 78 1.1E-11 T 29-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 SMALA_RS28765 c44a151b0ec84b625ecda48ab5b92759 160 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 133 151 1.1E-11 T 29-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 SMALA_RS28765 c44a151b0ec84b625ecda48ab5b92759 160 SUPERFAMILY SSF47240 3 153 4.96E-45 T 29-03-2018 IPR009078 Ferritin-like superfamily SMALA_RS28765 c44a151b0ec84b625ecda48ab5b92759 160 Gene3D G3DSA:1.20.1260.10 4 159 6.6E-39 T 29-03-2018 IPR012347 Ferritin-related SMALA_RS28765 c44a151b0ec84b625ecda48ab5b92759 160 Pfam PF00210 Ferritin-like domain 18 153 6.9E-21 T 29-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 SMALA_RS28765 c44a151b0ec84b625ecda48ab5b92759 160 PIRSF PIRSF005900 1 160 5.5E-43 T 29-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 SMALA_RS08485 5bc08ab24861c091738b38f56d01c2b1 138 Gene3D G3DSA:3.30.300.20 43 138 1.4E-26 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta SMALA_RS08485 5bc08ab24861c091738b38f56d01c2b1 138 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 5 135 1.3E-51 T 29-03-2018 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 SMALA_RS08485 5bc08ab24861c091738b38f56d01c2b1 138 SUPERFAMILY SSF82784 1 136 9.42E-41 T 29-03-2018 IPR003718 OsmC/Ohr family SMALA_RS08485 5bc08ab24861c091738b38f56d01c2b1 138 Pfam PF02566 OsmC-like protein 37 135 2.4E-21 T 29-03-2018 IPR003718 OsmC/Ohr family SMALA_RS08485 5bc08ab24861c091738b38f56d01c2b1 138 Gene3D G3DSA:2.20.25.10 1 42 1.1E-17 T 29-03-2018 SMALA_RS08510 7b1e7cf2895a32511d560a01eded0b01 147 PRINTS PR00294 Streptomyces subtilisin inhibitor signature 41 67 1.5E-27 T 29-03-2018 IPR000691 Proteinase inhibitor I16, Streptomyces subtilisin-type inhibitor GO:0004867 SMALA_RS08510 7b1e7cf2895a32511d560a01eded0b01 147 PRINTS PR00294 Streptomyces subtilisin inhibitor signature 105 121 1.5E-27 T 29-03-2018 IPR000691 Proteinase inhibitor I16, Streptomyces subtilisin-type inhibitor GO:0004867 SMALA_RS08510 7b1e7cf2895a32511d560a01eded0b01 147 PRINTS PR00294 Streptomyces subtilisin inhibitor signature 122 138 1.5E-27 T 29-03-2018 IPR000691 Proteinase inhibitor I16, Streptomyces subtilisin-type inhibitor GO:0004867 SMALA_RS08510 7b1e7cf2895a32511d560a01eded0b01 147 SUPERFAMILY SSF55399 39 147 1.57E-38 T 29-03-2018 IPR023549 Subtilisin inhibitor GO:0004867 SMALA_RS08510 7b1e7cf2895a32511d560a01eded0b01 147 ProSitePatterns PS00999 Streptomyces subtilisin-type inhibitors signature. 67 85 - T 29-03-2018 IPR020054 Proteinase inhibitor I16, Streptomyces subtilisin-type inhibitor, conserved site GO:0004867 SMALA_RS08510 7b1e7cf2895a32511d560a01eded0b01 147 Pfam PF00720 Subtilisin inhibitor-like 41 133 2.1E-37 T 29-03-2018 IPR023549 Subtilisin inhibitor GO:0004867 SMALA_RS08510 7b1e7cf2895a32511d560a01eded0b01 147 ProDom PD004028 INHIBITOR PROTEASE SERINE DIRECT SEQUENCING SUBTILISIN PRECURSOR SIGNAL INHIBITOR-LIKE INHIBITOR 44 135 7.0E-42 T 29-03-2018 IPR023549 Subtilisin inhibitor GO:0004867 SMALA_RS08510 7b1e7cf2895a32511d560a01eded0b01 147 Gene3D G3DSA:3.30.350.10 40 147 1.9E-29 T 29-03-2018 IPR023549 Subtilisin inhibitor GO:0004867 SMALA_RS08510 7b1e7cf2895a32511d560a01eded0b01 147 Hamap MF_00778 Probable subtilase-type protease inhibitor [sti]. 39 147 31.8 T 29-03-2018 IPR000691 Proteinase inhibitor I16, Streptomyces subtilisin-type inhibitor GO:0004867 SMALA_RS06480 9cc44be18417e00b8d6e34cf088a5f32 880 Gene3D G3DSA:1.25.40.10 116 306 1.4E-24 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS06480 9cc44be18417e00b8d6e34cf088a5f32 880 Pfam PF00486 Transcriptional regulatory protein, C terminal 42 112 9.0E-5 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS06480 9cc44be18417e00b8d6e34cf088a5f32 880 SMART SM00862 34 112 0.0024 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS06480 9cc44be18417e00b8d6e34cf088a5f32 880 Pfam PF13191 AAA ATPase domain 507 693 3.7E-13 T 29-03-2018 SMALA_RS06480 9cc44be18417e00b8d6e34cf088a5f32 880 Gene3D G3DSA:1.10.10.10 11 115 1.8E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS06480 9cc44be18417e00b8d6e34cf088a5f32 880 SUPERFAMILY SSF55073 336 465 2.04E-9 T 29-03-2018 IPR029787 Nucleotide cyclase SMALA_RS06480 9cc44be18417e00b8d6e34cf088a5f32 880 Gene3D G3DSA:3.40.50.300 500 753 2.5E-7 T 29-03-2018 SMALA_RS06480 9cc44be18417e00b8d6e34cf088a5f32 880 SUPERFAMILY SSF48452 114 279 7.17E-37 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS06480 9cc44be18417e00b8d6e34cf088a5f32 880 SUPERFAMILY SSF52540 658 763 3.47E-9 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS06480 9cc44be18417e00b8d6e34cf088a5f32 880 SUPERFAMILY SSF52540 519 568 3.47E-9 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS06480 9cc44be18417e00b8d6e34cf088a5f32 880 SUPERFAMILY SSF46894 21 112 2.35E-12 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS06480 9cc44be18417e00b8d6e34cf088a5f32 880 Gene3D G3DSA:3.30.70.1230 327 498 1.4E-8 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 SMALA_RS06480 9cc44be18417e00b8d6e34cf088a5f32 880 Pfam PF03704 Bacterial transcriptional activator domain 119 264 1.9E-44 T 29-03-2018 IPR005158 Bacterial transcriptional activator domain SMALA_RS06480 9cc44be18417e00b8d6e34cf088a5f32 880 SMART SM01043 119 264 7.7E-47 T 29-03-2018 IPR005158 Bacterial transcriptional activator domain SMALA_RS18395 2637b52fb37d0afb8c93200de47c0a91 191 Gene3D G3DSA:3.20.19.10 16 191 6.9E-40 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel SMALA_RS18395 2637b52fb37d0afb8c93200de47c0a91 191 Pfam PF00694 Aconitase C-terminal domain 67 122 1.6E-17 T 29-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS18395 2637b52fb37d0afb8c93200de47c0a91 191 TIGRFAM TIGR02087 LEUD_arch: 3-isopropylmalate dehydratase, small subunit 23 177 2.0E-44 T 29-03-2018 IPR011827 Hydrolyase LeuD/HacB/DmdB GO:0008152|GO:0016836 KEGG: 00290+4.2.1.33 SMALA_RS18395 2637b52fb37d0afb8c93200de47c0a91 191 SUPERFAMILY SSF52016 21 178 8.83E-39 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel SMALA_RS14230 4fe435d608085ae7dc642da24b51cde7 610 Gene3D G3DSA:3.40.50.10490 464 608 4.5E-45 T 29-03-2018 SMALA_RS14230 4fe435d608085ae7dc642da24b51cde7 610 SUPERFAMILY SSF56235 2 239 2.4E-62 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SMALA_RS14230 4fe435d608085ae7dc642da24b51cde7 610 SUPERFAMILY SSF53697 250 610 1.21E-94 T 29-03-2018 SMALA_RS14230 4fe435d608085ae7dc642da24b51cde7 610 Gene3D G3DSA:3.60.20.10 2 244 1.1E-64 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SMALA_RS14230 4fe435d608085ae7dc642da24b51cde7 610 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 610 2.8E-218 T 29-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 SMALA_RS14230 4fe435d608085ae7dc642da24b51cde7 610 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 610 37.175 T 29-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 SMALA_RS14230 4fe435d608085ae7dc642da24b51cde7 610 Gene3D G3DSA:3.40.50.10490 245 463 2.9E-58 T 29-03-2018 SMALA_RS14230 4fe435d608085ae7dc642da24b51cde7 610 Pfam PF13522 Glutamine amidotransferase domain 67 198 6.1E-20 T 29-03-2018 SMALA_RS14230 4fe435d608085ae7dc642da24b51cde7 610 Pfam PF01380 SIS domain 300 422 4.1E-27 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 SMALA_RS14230 4fe435d608085ae7dc642da24b51cde7 610 Pfam PF01380 SIS domain 467 591 5.1E-17 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 SMALA_RS14165 89fe347cd9d0dd1ddbbff946f40ecb3b 481 Pfam PF00270 DEAD/DEAH box helicase 88 253 5.4E-44 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 SMALA_RS14165 89fe347cd9d0dd1ddbbff946f40ecb3b 481 Gene3D G3DSA:3.40.50.300 56 289 1.6E-52 T 29-03-2018 SMALA_RS14165 89fe347cd9d0dd1ddbbff946f40ecb3b 481 SMART SM00487 83 283 1.4E-51 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain SMALA_RS14165 89fe347cd9d0dd1ddbbff946f40ecb3b 481 Pfam PF00271 Helicase conserved C-terminal domain 301 398 1.6E-23 T 29-03-2018 IPR001650 Helicase, C-terminal SMALA_RS14165 89fe347cd9d0dd1ddbbff946f40ecb3b 481 SUPERFAMILY SSF52540 135 417 9.65E-64 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS14165 89fe347cd9d0dd1ddbbff946f40ecb3b 481 Gene3D G3DSA:3.40.50.300 290 481 5.7E-35 T 29-03-2018 SMALA_RS14165 89fe347cd9d0dd1ddbbff946f40ecb3b 481 SMART SM00490 317 398 1.5E-28 T 29-03-2018 IPR001650 Helicase, C-terminal SMALA_RS30535 8007d38b502d05b3f97a669e9caca6c9 539 ProSitePatterns PS00510 Malate synthase signature. 269 284 - T 29-03-2018 IPR019830 Malate synthase, conserved site GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 SMALA_RS30535 8007d38b502d05b3f97a669e9caca6c9 539 SUPERFAMILY SSF51645 20 538 1.57E-182 T 29-03-2018 IPR011076 Malate synthase-like GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 SMALA_RS30535 8007d38b502d05b3f97a669e9caca6c9 539 Pfam PF01274 Malate synthase 18 538 2.1E-203 T 29-03-2018 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 SMALA_RS30535 8007d38b502d05b3f97a669e9caca6c9 539 PIRSF PIRSF001363 3 539 2.9E-239 T 29-03-2018 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 SMALA_RS30535 8007d38b502d05b3f97a669e9caca6c9 539 Gene3D G3DSA:1.20.1220.12 420 538 3.7E-44 T 29-03-2018 SMALA_RS30535 8007d38b502d05b3f97a669e9caca6c9 539 TIGRFAM TIGR01344 malate_syn_A: malate synthase A 23 538 5.1E-251 T 29-03-2018 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 SMALA_RS30535 8007d38b502d05b3f97a669e9caca6c9 539 Gene3D G3DSA:3.20.20.360 82 419 4.1E-112 T 29-03-2018 SMALA_RS22545 f8fdf335e60af1ef570ee0fe0740c858 108 Pfam PF00276 Ribosomal protein L23 17 102 1.6E-33 T 29-03-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 SMALA_RS22545 f8fdf335e60af1ef570ee0fe0740c858 108 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 16 105 23.175 T 29-03-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 SMALA_RS22545 f8fdf335e60af1ef570ee0fe0740c858 108 Gene3D G3DSA:3.30.70.330 13 107 9.1E-36 T 29-03-2018 SMALA_RS22545 f8fdf335e60af1ef570ee0fe0740c858 108 ProSitePatterns PS00050 Ribosomal protein L23 signature. 88 103 - T 29-03-2018 IPR001014 Ribosomal protein L23/L25, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMALA_RS22545 f8fdf335e60af1ef570ee0fe0740c858 108 SUPERFAMILY SSF54189 13 105 1.98E-34 T 29-03-2018 IPR012678 Ribosomal protein L23/L15e core domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS15480 46b3285c5b2161ccff458acd6372a698 392 Gene3D G3DSA:1.25.40.10 94 237 6.4E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS15480 46b3285c5b2161ccff458acd6372a698 392 SUPERFAMILY SSF48452 130 235 4.17E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS15480 46b3285c5b2161ccff458acd6372a698 392 Gene3D G3DSA:1.25.40.10 254 361 0.0015 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS42300 95914f4796ba9ebc25b69219f8b86421 356 Pfam PF00196 Bacterial regulatory proteins, luxR family 288 335 7.0E-6 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS42300 95914f4796ba9ebc25b69219f8b86421 356 SMART SM00421 287 336 4.7E-4 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS42300 95914f4796ba9ebc25b69219f8b86421 356 Gene3D G3DSA:1.10.10.10 105 341 5.7E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS42300 95914f4796ba9ebc25b69219f8b86421 356 SUPERFAMILY SSF46894 288 342 7.14E-9 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS17420 ae624db55e0cc639f7fe57d9ae162240 549 SMART SM00490 422 499 5.9E-12 T 29-03-2018 IPR001650 Helicase, C-terminal SMALA_RS17420 ae624db55e0cc639f7fe57d9ae162240 549 Gene3D G3DSA:3.40.50.300 378 532 1.3E-20 T 29-03-2018 SMALA_RS17420 ae624db55e0cc639f7fe57d9ae162240 549 SUPERFAMILY SSF52540 136 342 5.97E-32 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS17420 ae624db55e0cc639f7fe57d9ae162240 549 SUPERFAMILY SSF52540 386 526 8.21E-29 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS17420 ae624db55e0cc639f7fe57d9ae162240 549 SUPERFAMILY SSF52540 277 353 8.21E-29 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS17420 ae624db55e0cc639f7fe57d9ae162240 549 Pfam PF04851 Type III restriction enzyme, res subunit 181 325 2.0E-12 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 SMALA_RS17420 ae624db55e0cc639f7fe57d9ae162240 549 Pfam PF13625 Helicase conserved C-terminal domain 5 133 1.6E-46 T 29-03-2018 IPR032830 Helicase XPB/Ssl2, N-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 SMALA_RS17420 ae624db55e0cc639f7fe57d9ae162240 549 Gene3D G3DSA:3.40.50.300 173 354 8.6E-27 T 29-03-2018 SMALA_RS17420 ae624db55e0cc639f7fe57d9ae162240 549 SMART SM00487 177 352 2.7E-20 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain SMALA_RS17420 ae624db55e0cc639f7fe57d9ae162240 549 Pfam PF16203 ERCC3/RAD25/XPB C-terminal helicase 352 542 2.1E-46 T 29-03-2018 IPR032438 ERCC3/RAD25/XPB helicase, C-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 SMALA_RS06700 66fe859c2c6288a4bce53a9759d9d3c2 574 Gene3D G3DSA:3.20.20.240 51 568 2.5E-203 T 29-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMALA_RS06700 66fe859c2c6288a4bce53a9759d9d3c2 574 Pfam PF01642 Methylmalonyl-CoA mutase 55 566 5.1E-205 T 29-03-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMALA_RS06700 66fe859c2c6288a4bce53a9759d9d3c2 574 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 54 571 9.5E-206 T 29-03-2018 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMALA_RS06700 66fe859c2c6288a4bce53a9759d9d3c2 574 SUPERFAMILY SSF51703 30 568 3.4E-196 T 29-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMALA_RS29345 b5f3748727de9ea77663489179483c97 389 SUPERFAMILY SSF48264 16 389 6.02E-80 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS29345 b5f3748727de9ea77663489179483c97 389 Gene3D G3DSA:1.10.630.10 8 389 9.9E-67 T 29-03-2018 SMALA_RS29345 b5f3748727de9ea77663489179483c97 389 Pfam PF00067 Cytochrome P450 261 359 2.1E-16 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS29345 b5f3748727de9ea77663489179483c97 389 PRINTS PR00359 B-class P450 signature 130 146 7.3E-44 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS29345 b5f3748727de9ea77663489179483c97 389 PRINTS PR00359 B-class P450 signature 280 307 7.3E-44 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS29345 b5f3748727de9ea77663489179483c97 389 PRINTS PR00359 B-class P450 signature 147 162 7.3E-44 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS29345 b5f3748727de9ea77663489179483c97 389 PRINTS PR00359 B-class P450 signature 260 271 7.3E-44 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS29345 b5f3748727de9ea77663489179483c97 389 PRINTS PR00359 B-class P450 signature 329 338 7.3E-44 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS29345 b5f3748727de9ea77663489179483c97 389 PRINTS PR00359 B-class P450 signature 83 94 7.3E-44 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS29345 b5f3748727de9ea77663489179483c97 389 PRINTS PR00359 B-class P450 signature 183 205 7.3E-44 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS29345 b5f3748727de9ea77663489179483c97 389 PRINTS PR00359 B-class P450 signature 338 349 7.3E-44 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS29345 b5f3748727de9ea77663489179483c97 389 PRINTS PR00359 B-class P450 signature 308 323 7.3E-44 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS28980 53625dceafdbd9706ad2dea1e7812d35 208 Pfam PF00440 Bacterial regulatory proteins, tetR family 34 70 1.9E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS28980 53625dceafdbd9706ad2dea1e7812d35 208 SUPERFAMILY SSF48498 84 201 3.5E-23 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS28980 53625dceafdbd9706ad2dea1e7812d35 208 SUPERFAMILY SSF46689 17 74 2.87E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS28980 53625dceafdbd9706ad2dea1e7812d35 208 Gene3D G3DSA:1.10.10.60 1 69 7.6E-14 T 29-03-2018 SMALA_RS28980 53625dceafdbd9706ad2dea1e7812d35 208 Pfam PF16859 Bacterial transcriptional repressor C-terminal 83 194 1.0E-28 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS28980 53625dceafdbd9706ad2dea1e7812d35 208 Gene3D G3DSA:1.10.357.10 70 205 8.3E-23 T 29-03-2018 SMALA_RS03365 1a0a30d4e26593795961949d356a96a4 831 Gene3D G3DSA:2.160.10.10 302 377 5.1E-14 T 29-03-2018 SMALA_RS03365 1a0a30d4e26593795961949d356a96a4 831 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 384 509 1.4E-12 T 29-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMALA_RS03365 1a0a30d4e26593795961949d356a96a4 831 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 532 632 8.2E-17 T 29-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMALA_RS03365 1a0a30d4e26593795961949d356a96a4 831 SUPERFAMILY SSF53738 637 741 2.59E-11 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMALA_RS03365 1a0a30d4e26593795961949d356a96a4 831 SUPERFAMILY SSF53738 530 634 1.73E-14 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMALA_RS03365 1a0a30d4e26593795961949d356a96a4 831 SUPERFAMILY SSF51161 244 431 8.25E-33 T 29-03-2018 IPR011004 Trimeric LpxA-like SMALA_RS03365 1a0a30d4e26593795961949d356a96a4 831 Gene3D G3DSA:2.160.10.10 235 301 2.0E-13 T 29-03-2018 SMALA_RS03365 1a0a30d4e26593795961949d356a96a4 831 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 268 301 4.6E-4 T 29-03-2018 IPR001451 Hexapeptide repeat SMALA_RS03365 1a0a30d4e26593795961949d356a96a4 831 Gene3D G3DSA:3.40.120.10 529 639 4.4E-17 T 29-03-2018 SMALA_RS03365 1a0a30d4e26593795961949d356a96a4 831 Gene3D G3DSA:3.40.120.10 640 741 5.0E-12 T 29-03-2018 SMALA_RS03365 1a0a30d4e26593795961949d356a96a4 831 Pfam PF00483 Nucleotidyl transferase 2 233 1.2E-52 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 SMALA_RS03365 1a0a30d4e26593795961949d356a96a4 831 Gene3D G3DSA:3.40.120.10 378 515 1.1E-12 T 29-03-2018 SMALA_RS03365 1a0a30d4e26593795961949d356a96a4 831 Gene3D G3DSA:3.30.310.50 742 831 3.7E-4 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMALA_RS03365 1a0a30d4e26593795961949d356a96a4 831 SUPERFAMILY SSF53448 269 325 8.88E-80 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS03365 1a0a30d4e26593795961949d356a96a4 831 SUPERFAMILY SSF53448 1 237 8.88E-80 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS03365 1a0a30d4e26593795961949d356a96a4 831 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 638 740 9.6E-6 T 29-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMALA_RS03365 1a0a30d4e26593795961949d356a96a4 831 SUPERFAMILY SSF55957 744 828 4.97E-12 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMALA_RS03365 1a0a30d4e26593795961949d356a96a4 831 Gene3D G3DSA:3.90.550.10 1 234 2.5E-66 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS21455 ef43a4396b3ea0fbdba61c61f112a79d 141 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 2 140 7.7E-52 T 29-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 SMALA_RS21455 ef43a4396b3ea0fbdba61c61f112a79d 141 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 141 31.004 T 29-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 SMALA_RS21455 ef43a4396b3ea0fbdba61c61f112a79d 141 SUPERFAMILY SSF69500 1 140 6.54E-47 T 29-03-2018 IPR023509 D-Tyr tRNAtyr deacylase-like domain SMALA_RS21455 ef43a4396b3ea0fbdba61c61f112a79d 141 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 1 141 3.4E-42 T 29-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 SMALA_RS21455 ef43a4396b3ea0fbdba61c61f112a79d 141 Gene3D G3DSA:3.50.80.10 1 141 8.0E-53 T 29-03-2018 IPR023509 D-Tyr tRNAtyr deacylase-like domain SMALA_RS42925 a24711b13e601fe4a12040a4544253bb 625 Gene3D G3DSA:3.40.50.980 104 257 2.6E-36 T 29-03-2018 SMALA_RS42925 a24711b13e601fe4a12040a4544253bb 625 ProSitePatterns PS00455 Putative AMP-binding domain signature. 97 108 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS42925 a24711b13e601fe4a12040a4544253bb 625 Gene3D G3DSA:2.30.38.10 258 330 1.8E-15 T 29-03-2018 SMALA_RS42925 a24711b13e601fe4a12040a4544253bb 625 SUPERFAMILY SSF56801 20 422 1.7E-73 T 29-03-2018 SMALA_RS42925 a24711b13e601fe4a12040a4544253bb 625 Pfam PF00501 AMP-binding enzyme 87 336 2.7E-49 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS42925 a24711b13e601fe4a12040a4544253bb 625 Gene3D G3DSA:3.40.50.980 11 78 0.01 T 29-03-2018 SMALA_RS42925 a24711b13e601fe4a12040a4544253bb 625 Gene3D G3DSA:3.40.50.980 79 103 4.2E-9 T 29-03-2018 SMALA_RS41125 a8b7c61335495cdd05d3ddc3c6eb6d5e 365 Gene3D G3DSA:3.40.50.2300 209 344 2.6E-40 T 29-03-2018 SMALA_RS41125 a8b7c61335495cdd05d3ddc3c6eb6d5e 365 ProSitePatterns PS00356 LacI-type HTH domain signature. 33 51 - T 29-03-2018 SMALA_RS41125 a8b7c61335495cdd05d3ddc3c6eb6d5e 365 Gene3D G3DSA:3.40.50.2300 85 208 1.8E-28 T 29-03-2018 SMALA_RS41125 a8b7c61335495cdd05d3ddc3c6eb6d5e 365 Pfam PF13377 Periplasmic binding protein-like domain 202 360 3.7E-36 T 29-03-2018 SMALA_RS41125 a8b7c61335495cdd05d3ddc3c6eb6d5e 365 Pfam PF00356 Bacterial regulatory proteins, lacI family 32 77 8.6E-15 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS41125 a8b7c61335495cdd05d3ddc3c6eb6d5e 365 SUPERFAMILY SSF47413 30 88 1.5E-16 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS41125 a8b7c61335495cdd05d3ddc3c6eb6d5e 365 SUPERFAMILY SSF53822 90 363 8.14E-58 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SMALA_RS41125 a8b7c61335495cdd05d3ddc3c6eb6d5e 365 Gene3D G3DSA:1.10.260.40 32 84 6.1E-22 T 29-03-2018 SMALA_RS41125 a8b7c61335495cdd05d3ddc3c6eb6d5e 365 SMART SM00354 30 100 2.7E-22 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS35915 1571708f0357cbf7a33fa66597973398 1613 SUPERFAMILY SSF81665 1404 1598 1.44E-48 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SMALA_RS35915 1571708f0357cbf7a33fa66597973398 1613 SUPERFAMILY SSF81665 931 1024 1.44E-48 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SMALA_RS35915 1571708f0357cbf7a33fa66597973398 1613 SUPERFAMILY SSF81665 733 800 1.44E-48 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SMALA_RS35915 1571708f0357cbf7a33fa66597973398 1613 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 870 884 2.3E-28 T 29-03-2018 SMALA_RS35915 1571708f0357cbf7a33fa66597973398 1613 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 1378 1390 2.3E-28 T 29-03-2018 SMALA_RS35915 1571708f0357cbf7a33fa66597973398 1613 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 1253 1264 2.3E-28 T 29-03-2018 SMALA_RS35915 1571708f0357cbf7a33fa66597973398 1613 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 1275 1285 2.3E-28 T 29-03-2018 SMALA_RS35915 1571708f0357cbf7a33fa66597973398 1613 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 1354 1373 2.3E-28 T 29-03-2018 SMALA_RS35915 1571708f0357cbf7a33fa66597973398 1613 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 1030 1044 2.3E-28 T 29-03-2018 SMALA_RS35915 1571708f0357cbf7a33fa66597973398 1613 Gene3D G3DSA:3.30.70.100 50 119 2.4E-4 T 29-03-2018 SMALA_RS35915 1571708f0357cbf7a33fa66597973398 1613 Gene3D G3DSA:2.70.150.10 671 931 3.3E-24 T 29-03-2018 SMALA_RS35915 1571708f0357cbf7a33fa66597973398 1613 Pfam PF00122 E1-E2 ATPase 833 1009 2.9E-37 T 29-03-2018 SMALA_RS35915 1571708f0357cbf7a33fa66597973398 1613 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 1032 1038 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 SMALA_RS35915 1571708f0357cbf7a33fa66597973398 1613 Pfam PF00689 Cation transporting ATPase, C-terminus 1439 1595 4.0E-14 T 29-03-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 SMALA_RS35915 1571708f0357cbf7a33fa66597973398 1613 Pfam PF00702 haloacid dehalogenase-like hydrolase 1026 1368 1.0E-27 T 29-03-2018 SMALA_RS35915 1571708f0357cbf7a33fa66597973398 1613 Gene3D G3DSA:3.40.50.1000 1253 1380 5.6E-34 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS35915 1571708f0357cbf7a33fa66597973398 1613 SUPERFAMILY SSF56784 1028 1048 1.27E-48 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS35915 1571708f0357cbf7a33fa66597973398 1613 SUPERFAMILY SSF56784 1207 1459 1.27E-48 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS35915 1571708f0357cbf7a33fa66597973398 1613 Gene3D G3DSA:1.20.1110.10 1381 1610 1.3E-28 T 29-03-2018 SMALA_RS35915 1571708f0357cbf7a33fa66597973398 1613 Gene3D G3DSA:3.40.1110.10 986 1252 9.4E-32 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 SMALA_RS35915 1571708f0357cbf7a33fa66597973398 1613 SUPERFAMILY SSF81660 1036 1152 3.27E-10 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 SMALA_RS35915 1571708f0357cbf7a33fa66597973398 1613 SUPERFAMILY SSF81653 833 929 5.49E-21 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 SMALA_RS35915 1571708f0357cbf7a33fa66597973398 1613 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 1319 1435 5.0E-27 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMALA_RS35915 1571708f0357cbf7a33fa66597973398 1613 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 834 1062 1.1E-27 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMALA_RS35915 1571708f0357cbf7a33fa66597973398 1613 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 1326 1342 2.1E-17 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMALA_RS35915 1571708f0357cbf7a33fa66597973398 1613 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 1354 1370 2.1E-17 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMALA_RS35915 1571708f0357cbf7a33fa66597973398 1613 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 1386 1411 2.1E-17 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMALA_RS35915 1571708f0357cbf7a33fa66597973398 1613 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 1210 1228 2.1E-17 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMALA_RS35915 1571708f0357cbf7a33fa66597973398 1613 SUPERFAMILY SSF55008 71 115 6.8E-5 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 SMALA_RS24200 82112e360a92f5cf7fffa1baffddcbde 1178 Pfam PF02559 CarD-like/TRCF domain 499 598 1.3E-30 T 29-03-2018 IPR003711 CarD-like/TRCF domain SMALA_RS24200 82112e360a92f5cf7fffa1baffddcbde 1178 Gene3D G3DSA:3.40.50.300 815 979 2.3E-23 T 29-03-2018 SMALA_RS24200 82112e360a92f5cf7fffa1baffddcbde 1178 SMART SM00487 623 822 1.0E-30 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain SMALA_RS24200 82112e360a92f5cf7fffa1baffddcbde 1178 SUPERFAMILY SSF52540 549 806 7.25E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS24200 82112e360a92f5cf7fffa1baffddcbde 1178 SUPERFAMILY SSF143517 1020 1174 9.29E-33 T 29-03-2018 SMALA_RS24200 82112e360a92f5cf7fffa1baffddcbde 1178 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 167 1106 0.0 T 29-03-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 SMALA_RS24200 82112e360a92f5cf7fffa1baffddcbde 1178 Gene3D G3DSA:3.40.50.300 368 810 5.7E-36 T 29-03-2018 SMALA_RS24200 82112e360a92f5cf7fffa1baffddcbde 1178 SUPERFAMILY SSF141259 492 571 1.57E-17 T 29-03-2018 IPR003711 CarD-like/TRCF domain SMALA_RS24200 82112e360a92f5cf7fffa1baffddcbde 1178 Pfam PF00271 Helicase conserved C-terminal domain 833 932 4.8E-14 T 29-03-2018 IPR001650 Helicase, C-terminal SMALA_RS24200 82112e360a92f5cf7fffa1baffddcbde 1178 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 44 1126 28.579 T 29-03-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 SMALA_RS24200 82112e360a92f5cf7fffa1baffddcbde 1178 SMART SM00490 849 933 8.2E-16 T 29-03-2018 IPR001650 Helicase, C-terminal SMALA_RS24200 82112e360a92f5cf7fffa1baffddcbde 1178 SUPERFAMILY SSF52540 17 367 2.26E-71 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS24200 82112e360a92f5cf7fffa1baffddcbde 1178 Pfam PF03461 TRCF domain 1034 1116 2.4E-24 T 29-03-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 SMALA_RS24200 82112e360a92f5cf7fffa1baffddcbde 1178 SUPERFAMILY SSF52540 391 480 6.37E-12 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS24200 82112e360a92f5cf7fffa1baffddcbde 1178 Pfam PF00270 DEAD/DEAH box helicase 630 790 5.1E-16 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 SMALA_RS24200 82112e360a92f5cf7fffa1baffddcbde 1178 SMART SM01058 498 599 3.4E-46 T 29-03-2018 IPR003711 CarD-like/TRCF domain SMALA_RS24200 82112e360a92f5cf7fffa1baffddcbde 1178 SMART SM00982 1033 1131 1.1E-36 T 29-03-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 SMALA_RS24200 82112e360a92f5cf7fffa1baffddcbde 1178 SUPERFAMILY SSF52540 805 1013 3.88E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS16445 57c18c8cf98e39e5ff53dbb885d9cb52 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 224 1.3E-24 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS16445 57c18c8cf98e39e5ff53dbb885d9cb52 228 SUPERFAMILY SSF52172 7 175 7.18E-41 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS16445 57c18c8cf98e39e5ff53dbb885d9cb52 228 Gene3D G3DSA:1.10.10.10 125 228 1.6E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS16445 57c18c8cf98e39e5ff53dbb885d9cb52 228 Gene3D G3DSA:3.40.50.2300 4 124 2.6E-37 T 29-03-2018 SMALA_RS16445 57c18c8cf98e39e5ff53dbb885d9cb52 228 Pfam PF00072 Response regulator receiver domain 8 115 8.8E-29 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS16445 57c18c8cf98e39e5ff53dbb885d9cb52 228 SMART SM00862 148 224 1.0E-22 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS16445 57c18c8cf98e39e5ff53dbb885d9cb52 228 SMART SM00448 5 115 2.2E-40 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS19405 ef8e8b7d7294d065896dcaea3119c1a2 564 Pfam PF13185 GAF domain 214 340 1.1E-13 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS19405 ef8e8b7d7294d065896dcaea3119c1a2 564 SMART SM00387 462 561 1.7E-10 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS19405 ef8e8b7d7294d065896dcaea3119c1a2 564 Gene3D G3DSA:3.30.450.40 212 353 5.7E-22 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS19405 ef8e8b7d7294d065896dcaea3119c1a2 564 SMART SM00065 47 178 4.6E-9 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS19405 ef8e8b7d7294d065896dcaea3119c1a2 564 SMART SM00065 206 350 3.7E-10 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS19405 ef8e8b7d7294d065896dcaea3119c1a2 564 Pfam PF01590 GAF domain 47 168 1.3E-11 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS19405 ef8e8b7d7294d065896dcaea3119c1a2 564 Gene3D G3DSA:3.30.450.40 25 183 6.1E-22 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS19405 ef8e8b7d7294d065896dcaea3119c1a2 564 SUPERFAMILY SSF55781 31 195 1.18E-19 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS19405 ef8e8b7d7294d065896dcaea3119c1a2 564 Pfam PF07730 Histidine kinase 357 420 5.4E-14 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMALA_RS19405 ef8e8b7d7294d065896dcaea3119c1a2 564 SUPERFAMILY SSF55874 462 559 7.07E-11 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS19405 ef8e8b7d7294d065896dcaea3119c1a2 564 Gene3D G3DSA:3.30.565.10 379 560 5.5E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS19405 ef8e8b7d7294d065896dcaea3119c1a2 564 SUPERFAMILY SSF55781 213 340 5.23E-19 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS40215 c762fab6ada17e3a80529708bafd96cf 274 Pfam PF13490 Putative zinc-finger 8 40 2.8E-5 T 29-03-2018 IPR027383 Putative zinc-finger SMALA_RS20095 0db6ae7d3a253d4d9474a613bcff27b7 430 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 113 133 1.1E-36 T 29-03-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 SMALA_RS20095 0db6ae7d3a253d4d9474a613bcff27b7 430 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 395 410 1.1E-36 T 29-03-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 SMALA_RS20095 0db6ae7d3a253d4d9474a613bcff27b7 430 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 306 322 1.1E-36 T 29-03-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 SMALA_RS20095 0db6ae7d3a253d4d9474a613bcff27b7 430 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 263 281 1.1E-36 T 29-03-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 SMALA_RS20095 0db6ae7d3a253d4d9474a613bcff27b7 430 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 80 96 1.1E-36 T 29-03-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 SMALA_RS20095 0db6ae7d3a253d4d9474a613bcff27b7 430 Pfam PF02127 Aminopeptidase I zinc metalloprotease (M18) 18 427 4.0E-125 T 29-03-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 SMALA_RS20095 0db6ae7d3a253d4d9474a613bcff27b7 430 Gene3D G3DSA:3.40.630.10 200 430 4.8E-75 T 29-03-2018 SMALA_RS20095 0db6ae7d3a253d4d9474a613bcff27b7 430 Gene3D G3DSA:3.40.630.10 8 102 2.8E-30 T 29-03-2018 SMALA_RS20095 0db6ae7d3a253d4d9474a613bcff27b7 430 Gene3D G3DSA:2.30.250.10 103 199 6.1E-39 T 29-03-2018 SMALA_RS20095 0db6ae7d3a253d4d9474a613bcff27b7 430 SUPERFAMILY SSF101821 92 210 1.92E-31 T 29-03-2018 SMALA_RS20095 0db6ae7d3a253d4d9474a613bcff27b7 430 Hamap MF_00467 Probable M18 family aminopeptidase 2 [apeB]. 1 430 55.965 T 29-03-2018 IPR022984 M18 family aminopeptidase 2, putative GO:0004177 SMALA_RS20095 0db6ae7d3a253d4d9474a613bcff27b7 430 SUPERFAMILY SSF53187 211 429 2.92E-95 T 29-03-2018 SMALA_RS20095 0db6ae7d3a253d4d9474a613bcff27b7 430 SUPERFAMILY SSF53187 11 91 2.92E-95 T 29-03-2018 SMALA_RS34250 8f21eecd0085b91e82b9de382712bfe8 312 SUPERFAMILY SSF53850 88 289 3.98E-39 T 29-03-2018 SMALA_RS34250 8f21eecd0085b91e82b9de382712bfe8 312 Gene3D G3DSA:1.10.10.10 1 86 2.0E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS34250 8f21eecd0085b91e82b9de382712bfe8 312 Gene3D G3DSA:3.40.190.10 176 263 1.7E-20 T 29-03-2018 SMALA_RS34250 8f21eecd0085b91e82b9de382712bfe8 312 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 4.9E-15 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS34250 8f21eecd0085b91e82b9de382712bfe8 312 Gene3D G3DSA:3.40.190.10 89 175 8.5E-13 T 29-03-2018 SMALA_RS34250 8f21eecd0085b91e82b9de382712bfe8 312 Pfam PF03466 LysR substrate binding domain 101 291 1.4E-27 T 29-03-2018 IPR005119 LysR, substrate-binding SMALA_RS34250 8f21eecd0085b91e82b9de382712bfe8 312 SUPERFAMILY SSF46785 2 79 3.75E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS00135 3c578dd207a9dc298efed386ef508c1e 184 Gene3D G3DSA:1.10.10.60 26 68 1.8E-4 T 29-03-2018 SMALA_RS20555 228ba08ff2b9148898e15186e7b64d4c 401 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 8 30 3.6E-13 T 29-03-2018 SMALA_RS20555 228ba08ff2b9148898e15186e7b64d4c 401 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 275 282 3.6E-13 T 29-03-2018 SMALA_RS20555 228ba08ff2b9148898e15186e7b64d4c 401 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 149 174 3.6E-13 T 29-03-2018 SMALA_RS20555 228ba08ff2b9148898e15186e7b64d4c 401 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 235 249 3.6E-13 T 29-03-2018 SMALA_RS20555 228ba08ff2b9148898e15186e7b64d4c 401 Gene3D G3DSA:3.50.50.60 110 243 5.1E-26 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS20555 228ba08ff2b9148898e15186e7b64d4c 401 Gene3D G3DSA:3.30.390.30 324 398 3.3E-12 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SMALA_RS20555 228ba08ff2b9148898e15186e7b64d4c 401 Gene3D G3DSA:3.50.50.60 246 323 0.014 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS20555 228ba08ff2b9148898e15186e7b64d4c 401 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 105 123 9.2E-17 T 29-03-2018 SMALA_RS20555 228ba08ff2b9148898e15186e7b64d4c 401 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 234 250 9.2E-17 T 29-03-2018 SMALA_RS20555 228ba08ff2b9148898e15186e7b64d4c 401 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 260 282 9.2E-17 T 29-03-2018 SMALA_RS20555 228ba08ff2b9148898e15186e7b64d4c 401 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 149 167 9.2E-17 T 29-03-2018 SMALA_RS20555 228ba08ff2b9148898e15186e7b64d4c 401 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 9.2E-17 T 29-03-2018 SMALA_RS20555 228ba08ff2b9148898e15186e7b64d4c 401 SUPERFAMILY SSF55424 319 387 1.65E-9 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SMALA_RS20555 228ba08ff2b9148898e15186e7b64d4c 401 Pfam PF14759 Reductase C-terminal 327 386 3.4E-6 T 29-03-2018 IPR028202 Reductase, C-terminal SMALA_RS20555 228ba08ff2b9148898e15186e7b64d4c 401 Gene3D G3DSA:3.50.50.60 2 109 5.2E-9 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS20555 228ba08ff2b9148898e15186e7b64d4c 401 SUPERFAMILY SSF51905 4 313 1.89E-32 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS20555 228ba08ff2b9148898e15186e7b64d4c 401 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 305 1.7E-44 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS23540 0906ff092523bb2140f760c77b0ca87d 351 Pfam PF13404 AsnC-type helix-turn-helix domain 13 52 5.8E-11 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMALA_RS23540 0906ff092523bb2140f760c77b0ca87d 351 Gene3D G3DSA:1.10.10.10 181 239 3.8E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS23540 0906ff092523bb2140f760c77b0ca87d 351 Gene3D G3DSA:1.10.10.10 7 58 7.4E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS23540 0906ff092523bb2140f760c77b0ca87d 351 Gene3D G3DSA:3.30.70.920 240 326 5.6E-12 T 29-03-2018 SMALA_RS23540 0906ff092523bb2140f760c77b0ca87d 351 SUPERFAMILY SSF54909 243 322 2.15E-5 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel SMALA_RS23540 0906ff092523bb2140f760c77b0ca87d 351 SUPERFAMILY SSF46785 11 58 1.52E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS23540 0906ff092523bb2140f760c77b0ca87d 351 SMART SM00344 13 116 0.0077 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 SMALA_RS23540 0906ff092523bb2140f760c77b0ca87d 351 Gene3D G3DSA:3.30.70.920 70 157 3.6E-6 T 29-03-2018 SMALA_RS23540 0906ff092523bb2140f760c77b0ca87d 351 SUPERFAMILY SSF54909 73 154 4.16E-6 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel SMALA_RS26015 5007e0a17c37e3d469f3ed6c4db1a4ce 80 Pfam PF00462 Glutaredoxin 5 60 6.2E-13 T 29-03-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 SMALA_RS26015 5007e0a17c37e3d469f3ed6c4db1a4ce 80 SUPERFAMILY SSF52833 4 71 3.03E-16 T 29-03-2018 IPR012336 Thioredoxin-like fold SMALA_RS26015 5007e0a17c37e3d469f3ed6c4db1a4ce 80 Gene3D G3DSA:3.40.30.10 1 79 2.1E-16 T 29-03-2018 SMALA_RS26015 5007e0a17c37e3d469f3ed6c4db1a4ce 80 ProSitePatterns PS00194 Thioredoxin family active site. 5 23 - T 29-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 SMALA_RS26015 5007e0a17c37e3d469f3ed6c4db1a4ce 80 TIGRFAM TIGR02200 GlrX_actino: glutaredoxin-like protein 4 78 1.9E-32 T 29-03-2018 IPR011915 Glutaredoxin-like protein, actinobacteria SMALA_RS41705 465ef8732711d0e7997b8126e8a1232e 256 Gene3D G3DSA:3.40.1410.10 81 250 3.7E-33 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMALA_RS41705 465ef8732711d0e7997b8126e8a1232e 256 Pfam PF07702 UTRA domain 98 231 6.3E-26 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMALA_RS41705 465ef8732711d0e7997b8126e8a1232e 256 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 36 50 3.4E-10 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS41705 465ef8732711d0e7997b8126e8a1232e 256 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 50 66 3.4E-10 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS41705 465ef8732711d0e7997b8126e8a1232e 256 SUPERFAMILY SSF46785 10 92 2.81E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS41705 465ef8732711d0e7997b8126e8a1232e 256 Gene3D G3DSA:1.10.10.10 1 77 9.1E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS41705 465ef8732711d0e7997b8126e8a1232e 256 SUPERFAMILY SSF64288 64 240 3.77E-36 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMALA_RS41705 465ef8732711d0e7997b8126e8a1232e 256 SMART SM00866 97 236 1.7E-23 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMALA_RS41705 465ef8732711d0e7997b8126e8a1232e 256 SMART SM00345 17 76 2.6E-18 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS41705 465ef8732711d0e7997b8126e8a1232e 256 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 72 3.0E-19 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS29335 1f69d4373d57d81328ef30de7b941669 415 PRINTS PR00359 B-class P450 signature 101 112 2.7E-36 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS29335 1f69d4373d57d81328ef30de7b941669 415 PRINTS PR00359 B-class P450 signature 209 231 2.7E-36 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS29335 1f69d4373d57d81328ef30de7b941669 415 PRINTS PR00359 B-class P450 signature 147 163 2.7E-36 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS29335 1f69d4373d57d81328ef30de7b941669 415 PRINTS PR00359 B-class P450 signature 164 179 2.7E-36 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS29335 1f69d4373d57d81328ef30de7b941669 415 PRINTS PR00359 B-class P450 signature 290 301 2.7E-36 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS29335 1f69d4373d57d81328ef30de7b941669 415 PRINTS PR00359 B-class P450 signature 307 334 2.7E-36 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS29335 1f69d4373d57d81328ef30de7b941669 415 PRINTS PR00359 B-class P450 signature 365 376 2.7E-36 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS29335 1f69d4373d57d81328ef30de7b941669 415 PRINTS PR00359 B-class P450 signature 356 365 2.7E-36 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS29335 1f69d4373d57d81328ef30de7b941669 415 Gene3D G3DSA:1.10.630.10 7 415 7.0E-60 T 29-03-2018 SMALA_RS29335 1f69d4373d57d81328ef30de7b941669 415 Pfam PF00067 Cytochrome P450 291 381 7.3E-12 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS29335 1f69d4373d57d81328ef30de7b941669 415 Pfam PF00067 Cytochrome P450 102 275 1.2E-5 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS29335 1f69d4373d57d81328ef30de7b941669 415 SUPERFAMILY SSF48264 19 414 5.76E-75 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS29335 1f69d4373d57d81328ef30de7b941669 415 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 358 367 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMALA_RS16975 8100dc7d7020558b413d8a8283294be3 269 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 30 267 4.1E-63 T 29-03-2018 SMALA_RS16975 8100dc7d7020558b413d8a8283294be3 269 SUPERFAMILY SSF51735 23 267 5.16E-77 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS16975 8100dc7d7020558b413d8a8283294be3 269 Gene3D G3DSA:3.40.50.720 61 269 3.8E-60 T 29-03-2018 SMALA_RS16975 8100dc7d7020558b413d8a8283294be3 269 Gene3D G3DSA:3.40.50.720 17 60 5.2E-11 T 29-03-2018 SMALA_RS16975 8100dc7d7020558b413d8a8283294be3 269 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 99 110 2.2E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS16975 8100dc7d7020558b413d8a8283294be3 269 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 174 193 2.2E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS16975 8100dc7d7020558b413d8a8283294be3 269 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 162 2.2E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS16975 8100dc7d7020558b413d8a8283294be3 269 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 24 205 0.0051 T 29-03-2018 SMALA_RS16975 8100dc7d7020558b413d8a8283294be3 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 164 1.2E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS16975 8100dc7d7020558b413d8a8283294be3 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 25 42 1.2E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS16975 8100dc7d7020558b413d8a8283294be3 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 99 110 1.2E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS16975 8100dc7d7020558b413d8a8283294be3 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 231 251 1.2E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS16975 8100dc7d7020558b413d8a8283294be3 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 193 1.2E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS16975 8100dc7d7020558b413d8a8283294be3 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 195 212 1.2E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS20850 6e6c24c04124f6fd09a2984c68e37039 421 SMART SM01209 101 283 1.4E-113 T 29-03-2018 SMALA_RS20850 6e6c24c04124f6fd09a2984c68e37039 421 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 101 283 1.1E-63 T 29-03-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 SMALA_RS20850 6e6c24c04124f6fd09a2984c68e37039 421 Gene3D G3DSA:3.90.600.10 318 416 2.9E-31 T 29-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 SMALA_RS20850 6e6c24c04124f6fd09a2984c68e37039 421 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 2 416 2.7E-144 T 29-03-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 SMALA_RS20850 6e6c24c04124f6fd09a2984c68e37039 421 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 277 284 - T 29-03-2018 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 SMALA_RS20850 6e6c24c04124f6fd09a2984c68e37039 421 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 416 40.748 T 29-03-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 SMALA_RS20850 6e6c24c04124f6fd09a2984c68e37039 421 Gene3D G3DSA:3.30.470.20 179 316 2.1E-58 T 29-03-2018 SMALA_RS20850 6e6c24c04124f6fd09a2984c68e37039 421 SUPERFAMILY SSF52440 2 101 1.92E-30 T 29-03-2018 IPR016185 Pre-ATP-grasp domain SMALA_RS20850 6e6c24c04124f6fd09a2984c68e37039 421 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 2 100 2.9E-30 T 29-03-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 SMALA_RS20850 6e6c24c04124f6fd09a2984c68e37039 421 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 319 413 8.9E-28 T 29-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 SMALA_RS20850 6e6c24c04124f6fd09a2984c68e37039 421 SMART SM01210 318 416 1.2E-41 T 29-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 SMALA_RS20850 6e6c24c04124f6fd09a2984c68e37039 421 SUPERFAMILY SSF51246 316 415 2.35E-25 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 SMALA_RS20850 6e6c24c04124f6fd09a2984c68e37039 421 SUPERFAMILY SSF56059 102 307 1.36E-54 T 29-03-2018 SMALA_RS20850 6e6c24c04124f6fd09a2984c68e37039 421 Gene3D G3DSA:3.30.1490.20 85 177 1.0E-20 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SMALA_RS20850 6e6c24c04124f6fd09a2984c68e37039 421 Gene3D G3DSA:3.40.50.20 2 84 2.4E-34 T 29-03-2018 SMALA_RS05830 4732535c386c158dfe7f15a895b9c1cd 116 Pfam PF12840 Helix-turn-helix domain 11 68 2.2E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS05830 4732535c386c158dfe7f15a895b9c1cd 116 SMART SM00418 11 89 9.3E-29 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS05830 4732535c386c158dfe7f15a895b9c1cd 116 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 3.5E-10 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS05830 4732535c386c158dfe7f15a895b9c1cd 116 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 13 28 3.5E-10 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS05830 4732535c386c158dfe7f15a895b9c1cd 116 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 45 60 3.5E-10 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS05830 4732535c386c158dfe7f15a895b9c1cd 116 SUPERFAMILY SSF46785 3 88 1.47E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS05830 4732535c386c158dfe7f15a895b9c1cd 116 Gene3D G3DSA:1.10.10.10 2 92 1.2E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS04925 a5a2362d4379830ace0d003a3b38c61b 1378 Pfam PF00175 Oxidoreductase NAD-binding domain 1236 1342 4.6E-14 T 29-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 SMALA_RS04925 a5a2362d4379830ace0d003a3b38c61b 1378 SUPERFAMILY SSF50692 564 708 9.72E-48 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain SMALA_RS04925 a5a2362d4379830ace0d003a3b38c61b 1378 SUPERFAMILY SSF63380 1009 1225 1.05E-51 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 SMALA_RS04925 a5a2362d4379830ace0d003a3b38c61b 1378 Pfam PF00258 Flavodoxin 845 965 3.5E-26 T 29-03-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 SMALA_RS04925 a5a2362d4379830ace0d003a3b38c61b 1378 Gene3D G3DSA:3.40.50.740 65 168 2.6E-17 T 29-03-2018 SMALA_RS04925 a5a2362d4379830ace0d003a3b38c61b 1378 SUPERFAMILY SSF52218 839 984 4.61E-45 T 29-03-2018 IPR029039 Flavoprotein-like domain SMALA_RS04925 a5a2362d4379830ace0d003a3b38c61b 1378 Gene3D G3DSA:3.40.50.360 830 995 7.2E-38 T 29-03-2018 IPR029039 Flavoprotein-like domain SMALA_RS04925 a5a2362d4379830ace0d003a3b38c61b 1378 SUPERFAMILY SSF52343 1223 1378 5.5E-48 T 29-03-2018 SMALA_RS04925 a5a2362d4379830ace0d003a3b38c61b 1378 Gene3D G3DSA:3.40.50.740 261 547 1.3E-73 T 29-03-2018 SMALA_RS04925 a5a2362d4379830ace0d003a3b38c61b 1378 Gene3D G3DSA:2.40.30.10 996 1218 4.8E-39 T 29-03-2018 SMALA_RS04925 a5a2362d4379830ace0d003a3b38c61b 1378 Gene3D G3DSA:3.40.228.10 169 259 2.4E-27 T 29-03-2018 SMALA_RS04925 a5a2362d4379830ace0d003a3b38c61b 1378 Pfam PF00384 Molybdopterin oxidoreductase 83 493 7.3E-71 T 29-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS04925 a5a2362d4379830ace0d003a3b38c61b 1378 Pfam PF01568 Molydopterin dinucleotide binding domain 592 702 1.5E-34 T 29-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 SMALA_RS04925 a5a2362d4379830ace0d003a3b38c61b 1378 Gene3D G3DSA:2.40.40.20 548 708 3.6E-47 T 29-03-2018 SMALA_RS04925 a5a2362d4379830ace0d003a3b38c61b 1378 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 1 57 2.3E-15 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS04925 a5a2362d4379830ace0d003a3b38c61b 1378 SMART SM00926 1 60 7.9E-17 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS04925 a5a2362d4379830ace0d003a3b38c61b 1378 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 1235 1254 6.9E-22 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 SMALA_RS04925 a5a2362d4379830ace0d003a3b38c61b 1378 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 1304 1320 6.9E-22 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 SMALA_RS04925 a5a2362d4379830ace0d003a3b38c61b 1378 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 1327 1335 6.9E-22 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 SMALA_RS04925 a5a2362d4379830ace0d003a3b38c61b 1378 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 1165 1172 6.9E-22 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 SMALA_RS04925 a5a2362d4379830ace0d003a3b38c61b 1378 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 1273 1284 6.9E-22 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 SMALA_RS04925 a5a2362d4379830ace0d003a3b38c61b 1378 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 1199 1208 6.9E-22 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 SMALA_RS04925 a5a2362d4379830ace0d003a3b38c61b 1378 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 1045 1055 6.9E-22 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 SMALA_RS04925 a5a2362d4379830ace0d003a3b38c61b 1378 SUPERFAMILY SSF53706 2 593 2.36E-187 T 29-03-2018 SMALA_RS04925 a5a2362d4379830ace0d003a3b38c61b 1378 Gene3D G3DSA:2.20.25.90 1 64 2.2E-17 T 29-03-2018 SMALA_RS04925 a5a2362d4379830ace0d003a3b38c61b 1378 Pfam PF00667 FAD binding domain 1011 1204 2.0E-22 T 29-03-2018 IPR003097 FAD-binding, type 1 GO:0016491|GO:0055114 SMALA_RS04925 a5a2362d4379830ace0d003a3b38c61b 1378 Gene3D G3DSA:3.40.50.80 1221 1377 2.0E-33 T 29-03-2018 SMALA_RS04925 a5a2362d4379830ace0d003a3b38c61b 1378 PRINTS PR00369 Flavodoxin signature 844 857 8.9E-11 T 29-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 SMALA_RS04925 a5a2362d4379830ace0d003a3b38c61b 1378 PRINTS PR00369 Flavodoxin signature 924 934 8.9E-11 T 29-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 SMALA_RS04925 a5a2362d4379830ace0d003a3b38c61b 1378 PRINTS PR00369 Flavodoxin signature 892 903 8.9E-11 T 29-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 SMALA_RS04925 a5a2362d4379830ace0d003a3b38c61b 1378 PRINTS PR00369 Flavodoxin signature 948 967 8.9E-11 T 29-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 SMALA_RS11800 35de54be864696e4593e93594b3fe144 522 SUPERFAMILY SSF103473 311 512 3.66E-35 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS11800 35de54be864696e4593e93594b3fe144 522 SUPERFAMILY SSF103473 34 228 3.66E-35 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS11800 35de54be864696e4593e93594b3fe144 522 Pfam PF07690 Major Facilitator Superfamily 47 412 9.8E-14 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS11800 35de54be864696e4593e93594b3fe144 522 Gene3D G3DSA:1.20.1250.20 308 517 5.2E-14 T 29-03-2018 SMALA_RS11800 35de54be864696e4593e93594b3fe144 522 Gene3D G3DSA:1.20.1250.20 25 251 4.2E-10 T 29-03-2018 SMALA_RS28650 27d5d0952579342c730a3a8dff7e55a1 459 SUPERFAMILY SSF63411 34 238 1.52E-57 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 SMALA_RS28650 27d5d0952579342c730a3a8dff7e55a1 459 Gene3D G3DSA:3.30.830.10 12 247 4.7E-55 T 29-03-2018 SMALA_RS28650 27d5d0952579342c730a3a8dff7e55a1 459 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 66 89 - T 29-03-2018 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 SMALA_RS28650 27d5d0952579342c730a3a8dff7e55a1 459 SUPERFAMILY SSF63411 265 456 3.35E-48 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 SMALA_RS28650 27d5d0952579342c730a3a8dff7e55a1 459 Pfam PF00675 Insulinase (Peptidase family M16) 45 192 2.8E-34 T 29-03-2018 IPR011765 Peptidase M16, N-terminal SMALA_RS28650 27d5d0952579342c730a3a8dff7e55a1 459 Pfam PF05193 Peptidase M16 inactive domain 200 380 6.8E-43 T 29-03-2018 IPR007863 Peptidase M16, C-terminal SMALA_RS28650 27d5d0952579342c730a3a8dff7e55a1 459 Gene3D G3DSA:3.30.830.10 278 452 2.8E-49 T 29-03-2018 SMALA_RS41190 dfd9e7b98f895417bafa74e4d1379ab8 256 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS41190 dfd9e7b98f895417bafa74e4d1379ab8 256 SMART SM00382 36 226 3.8E-18 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS41190 dfd9e7b98f895417bafa74e4d1379ab8 256 Pfam PF00005 ABC transporter 27 172 2.0E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS41190 dfd9e7b98f895417bafa74e4d1379ab8 256 Gene3D G3DSA:3.40.50.300 2 234 3.0E-62 T 29-03-2018 SMALA_RS41190 dfd9e7b98f895417bafa74e4d1379ab8 256 SUPERFAMILY SSF52540 10 232 4.15E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS41190 dfd9e7b98f895417bafa74e4d1379ab8 256 TIGRFAM TIGR03771 anch_rpt_ABC: anchored repeat-type ABC transporter, ATP-binding subunit 33 253 5.2E-102 T 29-03-2018 IPR022508 ABC transporter, anchored repeat-type, ATP-binding subunit SMALA_RS01490 d4a3c6bf08d3c9d76db706342975dd42 339 PIRSF PIRSF015753 2 309 1.7E-105 T 29-03-2018 IPR016639 Glutathione S-transferase (GST) KEGG: 00480+2.5.1.18|KEGG: 00980+2.5.1.18|KEGG: 00982+2.5.1.18|MetaCyc: PWY-4061|MetaCyc: PWY-6842|MetaCyc: PWY-7112|MetaCyc: PWY-7533 SMALA_RS01490 d4a3c6bf08d3c9d76db706342975dd42 339 SUPERFAMILY SSF47616 162 321 7.8E-31 T 29-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like SMALA_RS01490 d4a3c6bf08d3c9d76db706342975dd42 339 Pfam PF13410 Glutathione S-transferase, C-terminal domain 190 247 3.9E-12 T 29-03-2018 SMALA_RS01490 d4a3c6bf08d3c9d76db706342975dd42 339 Gene3D G3DSA:1.20.1050.10 173 313 2.1E-41 T 29-03-2018 SMALA_RS01490 d4a3c6bf08d3c9d76db706342975dd42 339 Pfam PF13409 Glutathione S-transferase, N-terminal domain 48 142 3.3E-7 T 29-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 SMALA_RS01490 d4a3c6bf08d3c9d76db706342975dd42 339 SUPERFAMILY SSF52833 24 97 2.8E-5 T 29-03-2018 IPR012336 Thioredoxin-like fold SMALA_RS01490 d4a3c6bf08d3c9d76db706342975dd42 339 Gene3D G3DSA:3.40.30.10 18 172 5.2E-23 T 29-03-2018 SMALA_RS33215 c304663041216ce1c01b37f838642299 487 SUPERFAMILY SSF51412 222 481 2.35E-91 T 29-03-2018 SMALA_RS33215 c304663041216ce1c01b37f838642299 487 SUPERFAMILY SSF51412 19 101 2.35E-91 T 29-03-2018 SMALA_RS33215 c304663041216ce1c01b37f838642299 487 Pfam PF00571 CBS domain 158 210 1.4E-6 T 29-03-2018 IPR000644 CBS domain SMALA_RS33215 c304663041216ce1c01b37f838642299 487 Pfam PF00571 CBS domain 107 149 1.8E-4 T 29-03-2018 IPR000644 CBS domain SMALA_RS33215 c304663041216ce1c01b37f838642299 487 Gene3D G3DSA:3.20.20.70 7 477 7.5E-86 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS33215 c304663041216ce1c01b37f838642299 487 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 21 481 9.3E-102 T 29-03-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 SMALA_RS33215 c304663041216ce1c01b37f838642299 487 PIRSF PIRSF000130 10 487 3.1E-146 T 29-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 SMALA_RS33215 c304663041216ce1c01b37f838642299 487 SUPERFAMILY SSF54631 103 211 7.71E-19 T 29-03-2018 SMALA_RS33215 c304663041216ce1c01b37f838642299 487 SMART SM00116 106 153 3.1 T 29-03-2018 IPR000644 CBS domain SMALA_RS33215 c304663041216ce1c01b37f838642299 487 SMART SM00116 164 212 2.1 T 29-03-2018 IPR000644 CBS domain SMALA_RS33215 c304663041216ce1c01b37f838642299 487 TIGRFAM TIGR01303 IMP_DH_rel_1: IMP dehydrogenase family protein 10 484 9.1E-272 T 29-03-2018 IPR005991 IMP dehydrogenase-related 1 SMALA_RS33215 c304663041216ce1c01b37f838642299 487 SMART SM01240 19 482 1.5E-195 T 29-03-2018 SMALA_RS16800 bfb0df52322a9fc41006f6a9744f22a9 669 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 173 334 1.1E-14 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS16800 bfb0df52322a9fc41006f6a9744f22a9 669 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 497 656 2.5E-18 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS16800 bfb0df52322a9fc41006f6a9744f22a9 669 SUPERFAMILY SSF161098 475 658 9.68E-32 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS16800 bfb0df52322a9fc41006f6a9744f22a9 669 Gene3D G3DSA:1.10.3720.10 36 344 4.2E-27 T 29-03-2018 SMALA_RS16800 bfb0df52322a9fc41006f6a9744f22a9 669 Gene3D G3DSA:1.10.3720.10 473 654 5.8E-26 T 29-03-2018 SMALA_RS16800 bfb0df52322a9fc41006f6a9744f22a9 669 SUPERFAMILY SSF161098 153 335 3.66E-32 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS08460 95f6d4efe894c9f15e6a4eb9c7ce1b83 637 Pfam PF06276 Ferric iron reductase FhuF-like transporter 440 601 4.8E-9 T 29-03-2018 IPR022770 Ferric iron reductase FhuF domain SMALA_RS08460 95f6d4efe894c9f15e6a4eb9c7ce1b83 637 Pfam PF04183 IucA / IucC family 196 415 7.2E-29 T 29-03-2018 IPR007310 Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal GO:0015343|GO:0019290 SMALA_RS09190 4a63e00b6075cda6fd074107ac00c8e0 198 Gene3D G3DSA:3.40.50.300 6 198 5.4E-64 T 29-03-2018 SMALA_RS09190 4a63e00b6075cda6fd074107ac00c8e0 198 TIGRFAM TIGR00708 cobA: cob(I)yrinic acid a,c-diamide adenosyltransferase 19 198 1.0E-67 T 29-03-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 SMALA_RS09190 4a63e00b6075cda6fd074107ac00c8e0 198 Pfam PF02572 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 22 198 9.8E-59 T 29-03-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 SMALA_RS09190 4a63e00b6075cda6fd074107ac00c8e0 198 PIRSF PIRSF015617 1 198 6.6E-63 T 29-03-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 SMALA_RS09190 4a63e00b6075cda6fd074107ac00c8e0 198 SUPERFAMILY SSF52540 12 198 7.19E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS06185 4fc6dd2783a55647a0a25fd23937fab3 231 SUPERFAMILY SSF52172 3 129 1.42E-32 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS06185 4fc6dd2783a55647a0a25fd23937fab3 231 Gene3D G3DSA:1.10.10.10 130 222 1.4E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS06185 4fc6dd2783a55647a0a25fd23937fab3 231 ProSitePatterns PS00622 LuxR-type HTH domain signature. 172 199 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS06185 4fc6dd2783a55647a0a25fd23937fab3 231 SMART SM00421 155 212 2.5E-24 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS06185 4fc6dd2783a55647a0a25fd23937fab3 231 Pfam PF00196 Bacterial regulatory proteins, luxR family 157 212 1.5E-19 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS06185 4fc6dd2783a55647a0a25fd23937fab3 231 Gene3D G3DSA:3.40.50.2300 2 129 1.1E-32 T 29-03-2018 SMALA_RS06185 4fc6dd2783a55647a0a25fd23937fab3 231 Pfam PF00072 Response regulator receiver domain 5 119 8.4E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS06185 4fc6dd2783a55647a0a25fd23937fab3 231 SUPERFAMILY SSF46894 142 218 7.14E-23 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS06185 4fc6dd2783a55647a0a25fd23937fab3 231 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 172 2.1E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS06185 4fc6dd2783a55647a0a25fd23937fab3 231 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 188 2.1E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS06185 4fc6dd2783a55647a0a25fd23937fab3 231 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 188 200 2.1E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS06185 4fc6dd2783a55647a0a25fd23937fab3 231 SMART SM00448 3 118 3.5E-29 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS33600 8fd32cec38bdef3e23f498b8917f5855 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 1.8E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS33600 8fd32cec38bdef3e23f498b8917f5855 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 1.8E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS33600 8fd32cec38bdef3e23f498b8917f5855 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 1.8E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS33600 8fd32cec38bdef3e23f498b8917f5855 256 SUPERFAMILY SSF51735 5 256 3.64E-77 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS33600 8fd32cec38bdef3e23f498b8917f5855 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 254 7.0E-62 T 29-03-2018 SMALA_RS33600 8fd32cec38bdef3e23f498b8917f5855 256 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMALA_RS33600 8fd32cec38bdef3e23f498b8917f5855 256 Gene3D G3DSA:3.40.50.720 1 45 2.7E-8 T 29-03-2018 SMALA_RS33600 8fd32cec38bdef3e23f498b8917f5855 256 Gene3D G3DSA:3.40.50.720 46 256 2.2E-58 T 29-03-2018 SMALA_RS33600 8fd32cec38bdef3e23f498b8917f5855 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 7.8E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS33600 8fd32cec38bdef3e23f498b8917f5855 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 7.8E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS33600 8fd32cec38bdef3e23f498b8917f5855 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 7.8E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS33600 8fd32cec38bdef3e23f498b8917f5855 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 7.8E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS33600 8fd32cec38bdef3e23f498b8917f5855 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 7.8E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS33600 8fd32cec38bdef3e23f498b8917f5855 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 7.8E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS27090 1061d74adcdbe42ee35e54fec748c053 212 Gene3D G3DSA:3.60.160.10 1 212 1.0E-44 T 29-03-2018 IPR002838 Mitochondrial biogenesis protein AIM24 SMALA_RS27090 1061d74adcdbe42ee35e54fec748c053 212 Pfam PF01987 Mitochondrial biogenesis AIM24 5 202 1.6E-33 T 29-03-2018 IPR002838 Mitochondrial biogenesis protein AIM24 SMALA_RS27090 1061d74adcdbe42ee35e54fec748c053 212 SUPERFAMILY SSF51219 9 207 7.59E-45 T 29-03-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain SMALA_RS16685 65df7a7368a5ceb38ea56e31557d5220 126 PIRSF PIRSF000178 2 116 4.1E-10 T 29-03-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMALA_RS16685 65df7a7368a5ceb38ea56e31557d5220 126 Gene3D G3DSA:1.20.1300.10 5 118 6.6E-29 T 29-03-2018 SMALA_RS16685 65df7a7368a5ceb38ea56e31557d5220 126 TIGRFAM TIGR02970 succ_dehyd_cytB: succinate dehydrogenase, cytochrome b556 subunit 6 111 7.5E-30 T 29-03-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMALA_RS16685 65df7a7368a5ceb38ea56e31557d5220 126 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 5 108 6.4E-24 T 29-03-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMALA_RS16685 65df7a7368a5ceb38ea56e31557d5220 126 SUPERFAMILY SSF81343 2 113 1.29E-28 T 29-03-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMALA_RS21510 5111b5e48210056b6abe75c9ef99ca2d 564 Pfam PF00005 ABC transporter 338 485 1.2E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS21510 5111b5e48210056b6abe75c9ef99ca2d 564 SMART SM00382 347 533 4.7E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS21510 5111b5e48210056b6abe75c9ef99ca2d 564 SUPERFAMILY SSF90123 2 298 1.83E-67 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMALA_RS21510 5111b5e48210056b6abe75c9ef99ca2d 564 Gene3D G3DSA:3.40.50.300 311 563 9.1E-66 T 29-03-2018 SMALA_RS21510 5111b5e48210056b6abe75c9ef99ca2d 564 Gene3D G3DSA:1.20.1560.10 1 301 2.0E-68 T 29-03-2018 SMALA_RS21510 5111b5e48210056b6abe75c9ef99ca2d 564 Pfam PF00664 ABC transporter transmembrane region 2 272 1.5E-42 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMALA_RS21510 5111b5e48210056b6abe75c9ef99ca2d 564 SUPERFAMILY SSF52540 317 557 9.06E-80 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS21510 5111b5e48210056b6abe75c9ef99ca2d 564 ProSitePatterns PS00211 ABC transporters family signature. 459 473 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS33695 9a9c1b5be02d8deb69f4c594d60cdf63 146 ProSitePatterns PS00519 AsnC-type HTH domain signature. 19 45 - T 29-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site SMALA_RS33695 9a9c1b5be02d8deb69f4c594d60cdf63 146 SUPERFAMILY SSF46785 2 60 2.02E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS33695 9a9c1b5be02d8deb69f4c594d60cdf63 146 SUPERFAMILY SSF54909 61 143 1.47E-15 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel SMALA_RS33695 9a9c1b5be02d8deb69f4c594d60cdf63 146 SMART SM00344 3 108 5.8E-45 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 SMALA_RS33695 9a9c1b5be02d8deb69f4c594d60cdf63 146 Gene3D G3DSA:3.30.70.920 53 145 1.3E-21 T 29-03-2018 SMALA_RS33695 9a9c1b5be02d8deb69f4c594d60cdf63 146 Pfam PF01037 Lrp/AsnC ligand binding domain 67 137 1.5E-15 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain SMALA_RS33695 9a9c1b5be02d8deb69f4c594d60cdf63 146 Gene3D G3DSA:1.10.10.10 1 52 6.6E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS33695 9a9c1b5be02d8deb69f4c594d60cdf63 146 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 5.7E-16 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMALA_RS33695 9a9c1b5be02d8deb69f4c594d60cdf63 146 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 5.7E-16 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMALA_RS33695 9a9c1b5be02d8deb69f4c594d60cdf63 146 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 5.7E-16 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMALA_RS33695 9a9c1b5be02d8deb69f4c594d60cdf63 146 Pfam PF13404 AsnC-type helix-turn-helix domain 3 42 2.5E-16 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMALA_RS01735 d4f74c546141b3e15b3adefd1d5ac144 408 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 252 382 4.6E-10 T 29-03-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain SMALA_RS01735 d4f74c546141b3e15b3adefd1d5ac144 408 Gene3D G3DSA:2.40.110.10 131 231 7.4E-10 T 29-03-2018 SMALA_RS01735 d4f74c546141b3e15b3adefd1d5ac144 408 Gene3D G3DSA:1.20.140.10 244 407 1.1E-21 T 29-03-2018 SMALA_RS01735 d4f74c546141b3e15b3adefd1d5ac144 408 Gene3D G3DSA:1.10.540.10 11 130 1.3E-11 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS01735 d4f74c546141b3e15b3adefd1d5ac144 408 PIRSF PIRSF016578 243 390 9.1E-9 T 29-03-2018 SMALA_RS01735 d4f74c546141b3e15b3adefd1d5ac144 408 PIRSF PIRSF016578 11 198 5.2E-9 T 29-03-2018 SMALA_RS01735 d4f74c546141b3e15b3adefd1d5ac144 408 SUPERFAMILY SSF47203 248 403 5.48E-17 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMALA_RS01735 d4f74c546141b3e15b3adefd1d5ac144 408 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 30 107 5.5E-8 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS01735 d4f74c546141b3e15b3adefd1d5ac144 408 SUPERFAMILY SSF56645 25 230 9.95E-32 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMALA_RS34585 fa6383859ccd841a438eb2c23e227fb8 404 SUPERFAMILY SSF56300 2 318 1.48E-54 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SMALA_RS34585 fa6383859ccd841a438eb2c23e227fb8 404 TIGRFAM TIGR00619 sbcd: exonuclease SbcCD, D subunit 2 244 5.0E-55 T 29-03-2018 IPR004593 Nuclease SbcCD subunit D GO:0004519|GO:0006259|GO:0008408 SMALA_RS34585 fa6383859ccd841a438eb2c23e227fb8 404 Pfam PF12320 Type 5 capsule protein repressor C-terminal domain 268 355 1.5E-8 T 29-03-2018 IPR026843 Nuclease SbcCD subunit D, C-terminal domain SMALA_RS34585 fa6383859ccd841a438eb2c23e227fb8 404 Gene3D G3DSA:3.60.21.10 1 68 2.5E-14 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SMALA_RS34585 fa6383859ccd841a438eb2c23e227fb8 404 Gene3D G3DSA:3.60.21.10 69 269 1.0E-34 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SMALA_RS34585 fa6383859ccd841a438eb2c23e227fb8 404 Pfam PF00149 Calcineurin-like phosphoesterase 2 95 2.2E-11 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 SMALA_RS10320 f12fe7ef9bcdf9dcd9f8e66268928bb1 305 TIGRFAM TIGR00676 fadh2: methylenetetrahydrofolate reductase [NAD(P)H] 27 299 1.8E-99 T 29-03-2018 IPR004620 5,10-methylenetetrahydrofolate reductase GO:0004489|GO:0005829|GO:0009086|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841 SMALA_RS10320 f12fe7ef9bcdf9dcd9f8e66268928bb1 305 Gene3D G3DSA:3.20.20.220 5 305 1.5E-98 T 29-03-2018 IPR029041 FAD-linked oxidoreductase-like SMALA_RS10320 f12fe7ef9bcdf9dcd9f8e66268928bb1 305 Pfam PF02219 Methylenetetrahydrofolate reductase 16 300 2.5E-108 T 29-03-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 SMALA_RS10320 f12fe7ef9bcdf9dcd9f8e66268928bb1 305 SUPERFAMILY SSF51730 15 302 2.94E-95 T 29-03-2018 IPR029041 FAD-linked oxidoreductase-like SMALA_RS20660 18e91f7e1f21e21c91e3671e79f5113a 398 Gene3D G3DSA:2.60.260.20 143 285 2.9E-23 T 29-03-2018 SMALA_RS20660 18e91f7e1f21e21c91e3671e79f5113a 398 Gene3D G3DSA:1.10.287.110 6 142 3.0E-32 T 29-03-2018 IPR001623 DnaJ domain SMALA_RS20660 18e91f7e1f21e21c91e3671e79f5113a 398 Pfam PF00684 DnaJ central domain 178 238 9.3E-9 T 29-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 SMALA_RS20660 18e91f7e1f21e21c91e3671e79f5113a 398 SUPERFAMILY SSF57938 165 240 6.15E-13 T 29-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 SMALA_RS20660 18e91f7e1f21e21c91e3671e79f5113a 398 Pfam PF01556 DnaJ C terminal domain 151 364 1.9E-35 T 29-03-2018 IPR002939 Chaperone DnaJ, C-terminal SMALA_RS20660 18e91f7e1f21e21c91e3671e79f5113a 398 ProSitePatterns PS00636 Nt-dnaJ domain signature. 52 71 - T 29-03-2018 IPR018253 DnaJ domain, conserved site SMALA_RS20660 18e91f7e1f21e21c91e3671e79f5113a 398 SUPERFAMILY SSF49493 290 375 3.92E-21 T 29-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 SMALA_RS20660 18e91f7e1f21e21c91e3671e79f5113a 398 SMART SM00271 9 67 3.1E-30 T 29-03-2018 IPR001623 DnaJ domain SMALA_RS20660 18e91f7e1f21e21c91e3671e79f5113a 398 Pfam PF00226 DnaJ domain 10 72 3.7E-27 T 29-03-2018 IPR001623 DnaJ domain SMALA_RS20660 18e91f7e1f21e21c91e3671e79f5113a 398 SUPERFAMILY SSF46565 9 115 7.98E-30 T 29-03-2018 IPR001623 DnaJ domain SMALA_RS20660 18e91f7e1f21e21c91e3671e79f5113a 398 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 7 398 37.54 T 29-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 SMALA_RS20660 18e91f7e1f21e21c91e3671e79f5113a 398 Gene3D G3DSA:2.60.260.20 286 393 1.7E-26 T 29-03-2018 SMALA_RS20660 18e91f7e1f21e21c91e3671e79f5113a 398 PRINTS PR00625 DnaJ domain signature 12 30 1.6E-22 T 29-03-2018 IPR001623 DnaJ domain SMALA_RS20660 18e91f7e1f21e21c91e3671e79f5113a 398 PRINTS PR00625 DnaJ domain signature 67 86 1.6E-22 T 29-03-2018 IPR001623 DnaJ domain SMALA_RS20660 18e91f7e1f21e21c91e3671e79f5113a 398 PRINTS PR00625 DnaJ domain signature 30 45 1.6E-22 T 29-03-2018 IPR001623 DnaJ domain SMALA_RS20660 18e91f7e1f21e21c91e3671e79f5113a 398 PRINTS PR00625 DnaJ domain signature 47 67 1.6E-22 T 29-03-2018 IPR001623 DnaJ domain SMALA_RS20660 18e91f7e1f21e21c91e3671e79f5113a 398 SUPERFAMILY SSF49493 145 169 1.44E-20 T 29-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 SMALA_RS20660 18e91f7e1f21e21c91e3671e79f5113a 398 SUPERFAMILY SSF49493 231 297 1.44E-20 T 29-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 SMALA_RS20660 18e91f7e1f21e21c91e3671e79f5113a 398 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 10 381 1.2E-119 T 29-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 SMALA_RS38090 837a2d2ea0d931a67195417ceb860d59 140 Gene3D G3DSA:3.30.429.10 1 140 4.2E-43 T 29-03-2018 SMALA_RS38090 837a2d2ea0d931a67195417ceb860d59 140 SUPERFAMILY SSF55331 11 59 3.83E-6 T 29-03-2018 IPR014347 Tautomerase/MIF superfamily SMALA_RS38090 837a2d2ea0d931a67195417ceb860d59 140 Pfam PF14832 Putative oxalocrotonate tautomerase enzyme 1 136 9.7E-49 T 29-03-2018 IPR028116 Putative oxalocrotonate tautomerase SMALA_RS08690 ba33a9996f2f079a9a8d9e52e51248f3 487 Gene3D G3DSA:1.10.10.580 385 451 7.3E-9 T 29-03-2018 SMALA_RS08690 ba33a9996f2f079a9a8d9e52e51248f3 487 Pfam PF02616 Segregation and condensation protein ScpA 231 451 3.5E-47 T 29-03-2018 IPR003768 Segregation and condensation protein A SMALA_RS34925 a5d86e528eb963b92d39cfa488893f11 271 SUPERFAMILY SSF51735 18 261 2.49E-64 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS34925 a5d86e528eb963b92d39cfa488893f11 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 21 38 2.6E-27 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS34925 a5d86e528eb963b92d39cfa488893f11 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 227 247 2.6E-27 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS34925 a5d86e528eb963b92d39cfa488893f11 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 187 2.6E-27 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS34925 a5d86e528eb963b92d39cfa488893f11 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 189 206 2.6E-27 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS34925 a5d86e528eb963b92d39cfa488893f11 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 143 159 2.6E-27 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS34925 a5d86e528eb963b92d39cfa488893f11 271 Gene3D G3DSA:3.40.50.720 15 265 2.3E-65 T 29-03-2018 SMALA_RS34925 a5d86e528eb963b92d39cfa488893f11 271 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 28 260 1.4E-46 T 29-03-2018 SMALA_RS34925 a5d86e528eb963b92d39cfa488893f11 271 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 20 199 0.004 T 29-03-2018 SMALA_RS29105 b773e0a13f21030dd76b43a16f8b8626 457 Gene3D G3DSA:3.30.830.10 244 446 5.9E-19 T 29-03-2018 SMALA_RS29105 b773e0a13f21030dd76b43a16f8b8626 457 Pfam PF00675 Insulinase (Peptidase family M16) 35 151 1.6E-10 T 29-03-2018 IPR011765 Peptidase M16, N-terminal SMALA_RS29105 b773e0a13f21030dd76b43a16f8b8626 457 Gene3D G3DSA:3.30.830.10 21 236 1.9E-39 T 29-03-2018 SMALA_RS29105 b773e0a13f21030dd76b43a16f8b8626 457 SUPERFAMILY SSF63411 14 214 3.48E-38 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 SMALA_RS29105 b773e0a13f21030dd76b43a16f8b8626 457 Pfam PF05193 Peptidase M16 inactive domain 185 370 9.7E-19 T 29-03-2018 IPR007863 Peptidase M16, C-terminal SMALA_RS29105 b773e0a13f21030dd76b43a16f8b8626 457 SUPERFAMILY SSF63411 238 452 4.95E-19 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 SMALA_RS20305 242ffd3951666b280f0bacc3e037a432 561 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 363 475 2.1E-13 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS20305 242ffd3951666b280f0bacc3e037a432 561 SMART SM00387 361 478 2.6E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS20305 242ffd3951666b280f0bacc3e037a432 561 Gene3D G3DSA:1.10.287.130 238 312 5.5E-9 T 29-03-2018 SMALA_RS20305 242ffd3951666b280f0bacc3e037a432 561 PRINTS PR00344 Bacterial sensor protein C-terminal signature 424 434 3.3E-7 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS20305 242ffd3951666b280f0bacc3e037a432 561 PRINTS PR00344 Bacterial sensor protein C-terminal signature 406 420 3.3E-7 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS20305 242ffd3951666b280f0bacc3e037a432 561 PRINTS PR00344 Bacterial sensor protein C-terminal signature 436 454 3.3E-7 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS20305 242ffd3951666b280f0bacc3e037a432 561 SMART SM00388 249 316 7.4E-7 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS20305 242ffd3951666b280f0bacc3e037a432 561 Gene3D G3DSA:3.30.565.10 324 478 1.0E-25 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS20305 242ffd3951666b280f0bacc3e037a432 561 SUPERFAMILY SSF55874 323 475 1.06E-24 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS20305 242ffd3951666b280f0bacc3e037a432 561 SUPERFAMILY SSF47384 235 312 1.08E-10 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS20305 242ffd3951666b280f0bacc3e037a432 561 Pfam PF00512 His Kinase A (phospho-acceptor) domain 251 313 3.1E-9 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS33165 b8d690dbb71d4a5cff49a3833c51d2f2 490 SUPERFAMILY SSF53335 177 488 2.63E-50 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS33165 b8d690dbb71d4a5cff49a3833c51d2f2 490 Gene3D G3DSA:3.40.50.150 275 490 1.5E-42 T 29-03-2018 SMALA_RS33165 b8d690dbb71d4a5cff49a3833c51d2f2 490 Gene3D G3DSA:1.10.940.10 23 172 1.6E-29 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 SMALA_RS33165 b8d690dbb71d4a5cff49a3833c51d2f2 490 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 364 375 - T 29-03-2018 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SMALA_RS33165 b8d690dbb71d4a5cff49a3833c51d2f2 490 Pfam PF01189 16S rRNA methyltransferase RsmB/F 294 487 2.2E-42 T 29-03-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SMALA_RS33165 b8d690dbb71d4a5cff49a3833c51d2f2 490 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 266 280 2.5E-21 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SMALA_RS33165 b8d690dbb71d4a5cff49a3833c51d2f2 490 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 415 431 2.5E-21 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SMALA_RS33165 b8d690dbb71d4a5cff49a3833c51d2f2 490 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 299 309 2.5E-21 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SMALA_RS33165 b8d690dbb71d4a5cff49a3833c51d2f2 490 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 471 488 2.5E-21 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SMALA_RS33165 b8d690dbb71d4a5cff49a3833c51d2f2 490 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 365 377 2.5E-21 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SMALA_RS33165 b8d690dbb71d4a5cff49a3833c51d2f2 490 SUPERFAMILY SSF48013 28 191 1.7E-33 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 SMALA_RS33165 b8d690dbb71d4a5cff49a3833c51d2f2 490 Pfam PF01029 NusB family 28 159 6.8E-24 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 SMALA_RS35040 e286d01758daca53bad68ad5d3a533e0 227 SUPERFAMILY SSF51735 4 226 2.36E-51 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS35040 e286d01758daca53bad68ad5d3a533e0 227 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 1.7E-29 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS35040 e286d01758daca53bad68ad5d3a533e0 227 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 175 1.7E-29 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS35040 e286d01758daca53bad68ad5d3a533e0 227 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 137 156 1.7E-29 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS35040 e286d01758daca53bad68ad5d3a533e0 227 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 189 209 1.7E-29 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS35040 e286d01758daca53bad68ad5d3a533e0 227 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 67 78 1.7E-29 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS35040 e286d01758daca53bad68ad5d3a533e0 227 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 172 6.8E-4 T 29-03-2018 SMALA_RS35040 e286d01758daca53bad68ad5d3a533e0 227 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 67 78 1.1E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS35040 e286d01758daca53bad68ad5d3a533e0 227 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 118 126 1.1E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS35040 e286d01758daca53bad68ad5d3a533e0 227 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 156 1.1E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS35040 e286d01758daca53bad68ad5d3a533e0 227 Gene3D G3DSA:3.40.50.720 2 227 9.0E-52 T 29-03-2018 SMALA_RS35040 e286d01758daca53bad68ad5d3a533e0 227 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 225 2.7E-35 T 29-03-2018 SMALA_RS35100 96c3ce02aa1dbc10d2e4c5b3ed100df1 950 Pfam PF13424 Tetratricopeptide repeat 731 801 5.3E-12 T 29-03-2018 SMALA_RS35100 96c3ce02aa1dbc10d2e4c5b3ed100df1 950 Pfam PF13424 Tetratricopeptide repeat 810 882 1.9E-11 T 29-03-2018 SMALA_RS35100 96c3ce02aa1dbc10d2e4c5b3ed100df1 950 SUPERFAMILY SSF48452 94 266 1.77E-23 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS35100 96c3ce02aa1dbc10d2e4c5b3ed100df1 950 Pfam PF03704 Bacterial transcriptional activator domain 98 242 1.1E-28 T 29-03-2018 IPR005158 Bacterial transcriptional activator domain SMALA_RS35100 96c3ce02aa1dbc10d2e4c5b3ed100df1 950 Gene3D G3DSA:1.10.10.10 2 99 5.3E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS35100 96c3ce02aa1dbc10d2e4c5b3ed100df1 950 Pfam PF00486 Transcriptional regulatory protein, C terminal 18 76 1.9E-7 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS35100 96c3ce02aa1dbc10d2e4c5b3ed100df1 950 Gene3D G3DSA:3.30.70.100 860 887 3.2E-10 T 29-03-2018 SMALA_RS35100 96c3ce02aa1dbc10d2e4c5b3ed100df1 950 Gene3D G3DSA:3.30.70.100 774 806 2.9E-5 T 29-03-2018 SMALA_RS35100 96c3ce02aa1dbc10d2e4c5b3ed100df1 950 Gene3D G3DSA:3.30.70.100 702 773 7.3E-11 T 29-03-2018 SMALA_RS35100 96c3ce02aa1dbc10d2e4c5b3ed100df1 950 SUPERFAMILY SSF48452 724 923 6.32E-32 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS35100 96c3ce02aa1dbc10d2e4c5b3ed100df1 950 SUPERFAMILY SSF52540 270 543 5.83E-25 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS35100 96c3ce02aa1dbc10d2e4c5b3ed100df1 950 SMART SM00862 11 91 4.4E-9 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS35100 96c3ce02aa1dbc10d2e4c5b3ed100df1 950 Gene3D G3DSA:1.25.40.10 100 267 4.6E-17 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS35100 96c3ce02aa1dbc10d2e4c5b3ed100df1 950 Gene3D G3DSA:1.10.150.200 807 859 7.6E-15 T 29-03-2018 SMALA_RS35100 96c3ce02aa1dbc10d2e4c5b3ed100df1 950 Pfam PF00931 NB-ARC domain 307 545 9.9E-9 T 29-03-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207 SMALA_RS35100 96c3ce02aa1dbc10d2e4c5b3ed100df1 950 Gene3D G3DSA:3.40.50.300 268 425 1.8E-14 T 29-03-2018 SMALA_RS35100 96c3ce02aa1dbc10d2e4c5b3ed100df1 950 Gene3D G3DSA:1.25.40.10 888 939 2.6E-4 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS35100 96c3ce02aa1dbc10d2e4c5b3ed100df1 950 SUPERFAMILY SSF46894 2 91 1.45E-10 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS35100 96c3ce02aa1dbc10d2e4c5b3ed100df1 950 SMART SM00028 890 923 1.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS35100 96c3ce02aa1dbc10d2e4c5b3ed100df1 950 SMART SM00028 770 803 11.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS35100 96c3ce02aa1dbc10d2e4c5b3ed100df1 950 SMART SM00028 810 843 0.0013 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS35100 96c3ce02aa1dbc10d2e4c5b3ed100df1 950 SMART SM00028 850 883 0.006 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS35100 96c3ce02aa1dbc10d2e4c5b3ed100df1 950 SMART SM00028 730 763 15.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS35100 96c3ce02aa1dbc10d2e4c5b3ed100df1 950 SMART SM01043 98 243 1.8E-27 T 29-03-2018 IPR005158 Bacterial transcriptional activator domain SMALA_RS35100 96c3ce02aa1dbc10d2e4c5b3ed100df1 950 PRINTS PR00364 Disease resistance protein signature 386 400 9.7E-9 T 29-03-2018 SMALA_RS35100 96c3ce02aa1dbc10d2e4c5b3ed100df1 950 PRINTS PR00364 Disease resistance protein signature 474 488 9.7E-9 T 29-03-2018 SMALA_RS35100 96c3ce02aa1dbc10d2e4c5b3ed100df1 950 PRINTS PR00364 Disease resistance protein signature 307 322 9.7E-9 T 29-03-2018 SMALA_RS28375 4eff66f3a4237d8b86ea5cf1de16f478 722 SUPERFAMILY SSF52540 301 642 1.63E-11 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS28375 4eff66f3a4237d8b86ea5cf1de16f478 722 Gene3D G3DSA:3.40.50.300 275 711 1.6E-14 T 29-03-2018 SMALA_RS15115 f24e17f1547693cbf6ee297808a0d46c 455 Gene3D G3DSA:3.30.43.10 1 92 1.2E-21 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 SMALA_RS15115 f24e17f1547693cbf6ee297808a0d46c 455 SUPERFAMILY SSF56176 2 216 6.54E-68 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SMALA_RS15115 f24e17f1547693cbf6ee297808a0d46c 455 SUPERFAMILY SSF55103 191 454 1.34E-61 T 29-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 SMALA_RS15115 f24e17f1547693cbf6ee297808a0d46c 455 Pfam PF01565 FAD binding domain 40 179 9.1E-39 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 SMALA_RS15115 f24e17f1547693cbf6ee297808a0d46c 455 Gene3D G3DSA:3.30.465.10 93 237 4.4E-40 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SMALA_RS15115 f24e17f1547693cbf6ee297808a0d46c 455 Gene3D G3DSA:1.10.45.10 415 454 7.9E-17 T 29-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 SMALA_RS15115 f24e17f1547693cbf6ee297808a0d46c 455 Pfam PF02913 FAD linked oxidases, C-terminal domain 219 454 2.4E-66 T 29-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 SMALA_RS04360 92576e1610ac35c24fe8620e745809da 547 SUPERFAMILY SSF51905 20 193 3.8E-61 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS04360 92576e1610ac35c24fe8620e745809da 547 SUPERFAMILY SSF51905 282 386 3.8E-61 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS04360 92576e1610ac35c24fe8620e745809da 547 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 295 310 4.6E-35 T 29-03-2018 SMALA_RS04360 92576e1610ac35c24fe8620e745809da 547 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 328 346 4.6E-35 T 29-03-2018 SMALA_RS04360 92576e1610ac35c24fe8620e745809da 547 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 346 362 4.6E-35 T 29-03-2018 SMALA_RS04360 92576e1610ac35c24fe8620e745809da 547 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 172 187 4.6E-35 T 29-03-2018 SMALA_RS04360 92576e1610ac35c24fe8620e745809da 547 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 22 44 4.6E-35 T 29-03-2018 SMALA_RS04360 92576e1610ac35c24fe8620e745809da 547 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 310 326 4.6E-35 T 29-03-2018 SMALA_RS04360 92576e1610ac35c24fe8620e745809da 547 Gene3D G3DSA:3.50.50.60 19 402 3.2E-53 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS04360 92576e1610ac35c24fe8620e745809da 547 Pfam PF01494 FAD binding domain 20 360 1.7E-64 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 SMALA_RS42285 b54eaa36d93955de521bd6625881d799 289 Gene3D G3DSA:3.40.50.1820 2 276 2.7E-28 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS42285 b54eaa36d93955de521bd6625881d799 289 Pfam PF12146 Serine aminopeptidase, S33 31 250 3.2E-33 T 29-03-2018 IPR022742 Serine aminopeptidase, S33 SMALA_RS42285 b54eaa36d93955de521bd6625881d799 289 SUPERFAMILY SSF53474 12 261 2.7E-28 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS32705 9645106f2f3784f7e094d9c2cf354653 380 Gene3D G3DSA:3.50.50.60 3 342 2.1E-38 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS32705 9645106f2f3784f7e094d9c2cf354653 380 SUPERFAMILY SSF51905 265 368 5.19E-54 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS32705 9645106f2f3784f7e094d9c2cf354653 380 SUPERFAMILY SSF51905 4 166 5.19E-54 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS32705 9645106f2f3784f7e094d9c2cf354653 380 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 145 160 3.0E-13 T 29-03-2018 SMALA_RS32705 9645106f2f3784f7e094d9c2cf354653 380 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 3.0E-13 T 29-03-2018 SMALA_RS32705 9645106f2f3784f7e094d9c2cf354653 380 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 278 293 3.0E-13 T 29-03-2018 SMALA_RS32705 9645106f2f3784f7e094d9c2cf354653 380 Pfam PF01494 FAD binding domain 5 320 7.6E-19 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 SMALA_RS02790 ef422e489f9511a86736ab538e075e91 221 SUPERFAMILY SSF51735 4 195 2.62E-27 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS02790 ef422e489f9511a86736ab538e075e91 221 Gene3D G3DSA:3.40.50.720 2 189 1.3E-22 T 29-03-2018 SMALA_RS02790 ef422e489f9511a86736ab538e075e91 221 Pfam PF00106 short chain dehydrogenase 5 187 2.7E-17 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS12060 1d1560966cfc23e1c467e0a3c0573ed4 841 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 65 287 1.9E-52 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SMALA_RS12060 1d1560966cfc23e1c467e0a3c0573ed4 841 Pfam PF07691 PA14 domain 455 525 5.3E-5 T 29-03-2018 IPR011658 PA14 domain SMALA_RS12060 1d1560966cfc23e1c467e0a3c0573ed4 841 Gene3D G3DSA:2.60.40.10 727 838 5.7E-28 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS12060 1d1560966cfc23e1c467e0a3c0573ed4 841 SUPERFAMILY SSF51445 11 323 2.0E-89 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS12060 1d1560966cfc23e1c467e0a3c0573ed4 841 Gene3D G3DSA:3.20.20.300 9 309 4.0E-96 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SMALA_RS12060 1d1560966cfc23e1c467e0a3c0573ed4 841 SUPERFAMILY SSF52279 562 718 3.66E-50 T 29-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 SMALA_RS12060 1d1560966cfc23e1c467e0a3c0573ed4 841 SUPERFAMILY SSF52279 324 402 3.66E-50 T 29-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 SMALA_RS12060 1d1560966cfc23e1c467e0a3c0573ed4 841 PRINTS PR00133 Glycosyl hydrolase family 3 signature 149 165 2.9E-33 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SMALA_RS12060 1d1560966cfc23e1c467e0a3c0573ed4 841 PRINTS PR00133 Glycosyl hydrolase family 3 signature 72 91 2.9E-33 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SMALA_RS12060 1d1560966cfc23e1c467e0a3c0573ed4 841 PRINTS PR00133 Glycosyl hydrolase family 3 signature 219 237 2.9E-33 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SMALA_RS12060 1d1560966cfc23e1c467e0a3c0573ed4 841 PRINTS PR00133 Glycosyl hydrolase family 3 signature 118 134 2.9E-33 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SMALA_RS12060 1d1560966cfc23e1c467e0a3c0573ed4 841 PRINTS PR00133 Glycosyl hydrolase family 3 signature 43 59 2.9E-33 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SMALA_RS12060 1d1560966cfc23e1c467e0a3c0573ed4 841 SMART SM01217 751 826 2.2E-19 T 29-03-2018 IPR026891 Fibronectin type III-like domain SMALA_RS12060 1d1560966cfc23e1c467e0a3c0573ed4 841 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 325 694 2.5E-54 T 29-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 SMALA_RS12060 1d1560966cfc23e1c467e0a3c0573ed4 841 Gene3D G3DSA:3.40.50.1700 311 717 1.4E-77 T 29-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 SMALA_RS12060 1d1560966cfc23e1c467e0a3c0573ed4 841 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 219 236 - T 29-03-2018 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 SMALA_RS12060 1d1560966cfc23e1c467e0a3c0573ed4 841 SUPERFAMILY SSF56988 459 607 1.83E-6 T 29-03-2018 SMALA_RS12060 1d1560966cfc23e1c467e0a3c0573ed4 841 Pfam PF14310 Fibronectin type III-like domain 751 825 6.4E-17 T 29-03-2018 IPR026891 Fibronectin type III-like domain SMALA_RS13955 c5ba073b9a457dc7e8f598aaeaf742ee 649 Gene3D G3DSA:3.40.50.2300 491 644 6.2E-44 T 29-03-2018 SMALA_RS13955 c5ba073b9a457dc7e8f598aaeaf742ee 649 Gene3D G3DSA:1.10.3470.10 43 322 4.6E-37 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SMALA_RS13955 c5ba073b9a457dc7e8f598aaeaf742ee 649 Pfam PF13407 Periplasmic binding protein domain 381 634 2.4E-66 T 29-03-2018 IPR025997 Periplasmic binding protein SMALA_RS13955 c5ba073b9a457dc7e8f598aaeaf742ee 649 Gene3D G3DSA:3.40.50.2300 377 490 2.4E-26 T 29-03-2018 SMALA_RS13955 c5ba073b9a457dc7e8f598aaeaf742ee 649 SUPERFAMILY SSF53822 365 647 3.3E-86 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SMALA_RS13955 c5ba073b9a457dc7e8f598aaeaf742ee 649 Pfam PF02653 Branched-chain amino acid transport system / permease component 51 314 1.2E-45 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 SMALA_RS36620 b35ecf9524160fc44681bdf43367bbfc 219 SUPERFAMILY SSF54506 5 212 3.34E-26 T 29-03-2018 SMALA_RS36620 b35ecf9524160fc44681bdf43367bbfc 219 Pfam PF02567 Phenazine biosynthesis-like protein 17 82 3.9E-10 T 29-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 SMALA_RS36620 b35ecf9524160fc44681bdf43367bbfc 219 Gene3D G3DSA:3.10.310.10 24 210 9.9E-23 T 29-03-2018 SMALA_RS29305 e761490eebbd476dcae04cb7362a0c53 607 Gene3D G3DSA:3.40.50.920 453 583 4.8E-29 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMALA_RS29305 e761490eebbd476dcae04cb7362a0c53 607 ProSitePatterns PS00802 Transketolase signature 2. 384 400 - T 29-03-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SMALA_RS29305 e761490eebbd476dcae04cb7362a0c53 607 Gene3D G3DSA:3.40.50.970 269 450 6.7E-40 T 29-03-2018 SMALA_RS29305 e761490eebbd476dcae04cb7362a0c53 607 SMART SM00861 278 442 9.5E-52 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain SMALA_RS29305 e761490eebbd476dcae04cb7362a0c53 607 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 202 242 1.4E-8 T 29-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SMALA_RS29305 e761490eebbd476dcae04cb7362a0c53 607 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 4 196 1.9E-83 T 29-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SMALA_RS29305 e761490eebbd476dcae04cb7362a0c53 607 Gene3D G3DSA:3.40.50.970 1 268 1.5E-70 T 29-03-2018 SMALA_RS29305 e761490eebbd476dcae04cb7362a0c53 607 ProSitePatterns PS00801 Transketolase signature 1. 29 48 - T 29-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SMALA_RS29305 e761490eebbd476dcae04cb7362a0c53 607 SUPERFAMILY SSF52518 3 309 3.61E-66 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold SMALA_RS29305 e761490eebbd476dcae04cb7362a0c53 607 Pfam PF02780 Transketolase, C-terminal domain 461 573 1.7E-24 T 29-03-2018 IPR033248 Transketolase, C-terminal domain SMALA_RS29305 e761490eebbd476dcae04cb7362a0c53 607 SUPERFAMILY SSF52518 259 439 4.65E-52 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold SMALA_RS29305 e761490eebbd476dcae04cb7362a0c53 607 SUPERFAMILY SSF52922 463 581 1.44E-23 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMALA_RS29305 e761490eebbd476dcae04cb7362a0c53 607 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 3 582 38.724 T 29-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SMALA_RS29305 e761490eebbd476dcae04cb7362a0c53 607 Pfam PF02779 Transketolase, pyrimidine binding domain 279 438 1.6E-33 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain SMALA_RS05110 066905750dc58d41ac13c36575e0639d 232 Pfam PF11361 Protein of unknown function (DUF3159) 34 217 4.8E-62 T 29-03-2018 IPR016566 Uncharacterised conserved protein UCP010219 SMALA_RS05110 066905750dc58d41ac13c36575e0639d 232 PIRSF PIRSF010219 11 231 3.0E-66 T 29-03-2018 IPR016566 Uncharacterised conserved protein UCP010219 SMALA_RS14485 46cdbae6bc8482a9f51475f424a3e4aa 427 Gene3D G3DSA:3.40.50.300 3 211 6.2E-18 T 29-03-2018 SMALA_RS14485 46cdbae6bc8482a9f51475f424a3e4aa 427 SUPERFAMILY SSF52540 267 378 1.74E-24 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS14485 46cdbae6bc8482a9f51475f424a3e4aa 427 SUPERFAMILY SSF52540 11 236 1.74E-24 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS14485 46cdbae6bc8482a9f51475f424a3e4aa 427 Gene3D G3DSA:3.40.50.300 214 390 2.1E-7 T 29-03-2018 SMALA_RS14485 46cdbae6bc8482a9f51475f424a3e4aa 427 Pfam PF13604 AAA domain 3 156 2.1E-9 T 29-03-2018 SMALA_RS06175 9d466adf0597d69d0194c53ca5fe2cb5 464 Gene3D G3DSA:1.20.1250.20 260 464 9.3E-22 T 29-03-2018 SMALA_RS06175 9d466adf0597d69d0194c53ca5fe2cb5 464 Gene3D G3DSA:1.20.1250.20 7 199 8.2E-28 T 29-03-2018 SMALA_RS06175 9d466adf0597d69d0194c53ca5fe2cb5 464 SUPERFAMILY SSF103473 250 460 6.28E-54 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS06175 9d466adf0597d69d0194c53ca5fe2cb5 464 SUPERFAMILY SSF103473 15 204 6.28E-54 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS06175 9d466adf0597d69d0194c53ca5fe2cb5 464 Pfam PF07690 Major Facilitator Superfamily 21 322 1.0E-26 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS38620 a8600744444932a25b078d5f1a62f84c 288 Gene3D G3DSA:3.40.190.10 79 174 2.0E-17 T 29-03-2018 SMALA_RS38620 a8600744444932a25b078d5f1a62f84c 288 Gene3D G3DSA:1.10.10.10 1 78 1.3E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS38620 a8600744444932a25b078d5f1a62f84c 288 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 9.6E-21 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS38620 a8600744444932a25b078d5f1a62f84c 288 SUPERFAMILY SSF46785 1 83 5.53E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS38620 a8600744444932a25b078d5f1a62f84c 288 Pfam PF03466 LysR substrate binding domain 91 280 8.2E-23 T 29-03-2018 IPR005119 LysR, substrate-binding SMALA_RS38620 a8600744444932a25b078d5f1a62f84c 288 SUPERFAMILY SSF53850 91 283 3.8E-22 T 29-03-2018 SMALA_RS38620 a8600744444932a25b078d5f1a62f84c 288 Gene3D G3DSA:3.40.190.10 175 257 5.6E-9 T 29-03-2018 SMALA_RS38620 a8600744444932a25b078d5f1a62f84c 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 4.4E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS38620 a8600744444932a25b078d5f1a62f84c 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 4.4E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS38620 a8600744444932a25b078d5f1a62f84c 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 4.4E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS18980 691ee3a72253daab95abcf34dd1ee306 151 Gene3D G3DSA:1.10.3680.10 3 151 6.9E-25 T 29-03-2018 IPR029024 TerB-like SMALA_RS18980 691ee3a72253daab95abcf34dd1ee306 151 SUPERFAMILY SSF158682 21 150 2.35E-24 T 29-03-2018 SMALA_RS18980 691ee3a72253daab95abcf34dd1ee306 151 Pfam PF05099 Tellurite resistance protein TerB 11 150 1.4E-32 T 29-03-2018 IPR007791 Co-chaperone DjlA, N-terminal SMALA_RS00500 c2cfb6d6253e4d840817abdd5871c6b6 588 SUPERFAMILY SSF53756 147 323 3.45E-10 T 29-03-2018 SMALA_RS00500 c2cfb6d6253e4d840817abdd5871c6b6 588 Gene3D G3DSA:3.40.50.2000 191 357 1.8E-5 T 29-03-2018 SMALA_RS07875 cb7551dc573074ae26d1e95a14c50786 793 Pfam PF13245 AAA domain 286 548 3.1E-19 T 29-03-2018 SMALA_RS07875 cb7551dc573074ae26d1e95a14c50786 793 Pfam PF13361 UvrD-like helicase C-terminal domain 682 756 1.2E-15 T 29-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 SMALA_RS07875 cb7551dc573074ae26d1e95a14c50786 793 Gene3D G3DSA:3.40.50.300 562 778 1.1E-33 T 29-03-2018 SMALA_RS07875 cb7551dc573074ae26d1e95a14c50786 793 SUPERFAMILY SSF52540 429 760 1.11E-64 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS07875 cb7551dc573074ae26d1e95a14c50786 793 SUPERFAMILY SSF52540 267 392 1.11E-64 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS07875 cb7551dc573074ae26d1e95a14c50786 793 Gene3D G3DSA:3.40.50.300 269 556 6.0E-30 T 29-03-2018 SMALA_RS31320 242d0c4a5bd04eefe56244089cfbe8d6 332 Gene3D G3DSA:1.10.1040.10 198 325 4.2E-31 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMALA_RS31320 242d0c4a5bd04eefe56244089cfbe8d6 332 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 263 278 8.5E-5 T 29-03-2018 SMALA_RS31320 242d0c4a5bd04eefe56244089cfbe8d6 332 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 2 27 8.5E-5 T 29-03-2018 SMALA_RS31320 242d0c4a5bd04eefe56244089cfbe8d6 332 SUPERFAMILY SSF48179 198 317 5.78E-27 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMALA_RS31320 242d0c4a5bd04eefe56244089cfbe8d6 332 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 198 317 1.3E-26 T 29-03-2018 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 SMALA_RS31320 242d0c4a5bd04eefe56244089cfbe8d6 332 Gene3D G3DSA:3.40.50.720 1 197 1.8E-34 T 29-03-2018 SMALA_RS31320 242d0c4a5bd04eefe56244089cfbe8d6 332 SUPERFAMILY SSF51735 1 158 4.61E-11 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS31320 242d0c4a5bd04eefe56244089cfbe8d6 332 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 171 1.7E-23 T 29-03-2018 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 SMALA_RS00945 266fd1be61820003fbb132b62461f6ec 701 Gene3D G3DSA:3.30.365.10 153 260 1.8E-34 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMALA_RS00945 266fd1be61820003fbb132b62461f6ec 701 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 22 124 2.1E-21 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMALA_RS00945 266fd1be61820003fbb132b62461f6ec 701 Gene3D G3DSA:3.30.365.10 261 411 2.1E-35 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMALA_RS00945 266fd1be61820003fbb132b62461f6ec 701 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 152 637 4.4E-110 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMALA_RS00945 266fd1be61820003fbb132b62461f6ec 701 SUPERFAMILY SSF54665 6 129 3.14E-32 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMALA_RS00945 266fd1be61820003fbb132b62461f6ec 701 Gene3D G3DSA:3.30.365.10 434 548 1.3E-19 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMALA_RS00945 266fd1be61820003fbb132b62461f6ec 701 SMART SM01008 22 126 7.7E-31 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMALA_RS00945 266fd1be61820003fbb132b62461f6ec 701 Gene3D G3DSA:3.90.1170.50 6 125 3.1E-29 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMALA_RS00945 266fd1be61820003fbb132b62461f6ec 701 Gene3D G3DSA:3.30.365.10 549 701 2.8E-43 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMALA_RS00945 266fd1be61820003fbb132b62461f6ec 701 SUPERFAMILY SSF56003 130 698 4.32E-155 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMALA_RS03345 18446008cf466a48fd02fb90b5e6639e 256 Pfam PF00498 FHA domain 177 241 1.1E-18 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 SMALA_RS03345 18446008cf466a48fd02fb90b5e6639e 256 Gene3D G3DSA:2.20.28.20 76 104 1.7E-4 T 29-03-2018 SMALA_RS03345 18446008cf466a48fd02fb90b5e6639e 256 Gene3D G3DSA:2.60.200.20 133 250 1.1E-27 T 29-03-2018 SMALA_RS03345 18446008cf466a48fd02fb90b5e6639e 256 SMART SM00240 175 226 9.7E-13 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 SMALA_RS03345 18446008cf466a48fd02fb90b5e6639e 256 SUPERFAMILY SSF49879 137 248 2.68E-30 T 29-03-2018 IPR008984 SMAD/FHA domain GO:0005515 SMALA_RS03345 18446008cf466a48fd02fb90b5e6639e 256 Pfam PF13240 zinc-ribbon domain 80 101 2.3E-6 T 29-03-2018 IPR026870 Zinc-ribbon domain Reactome: R-HSA-202670 SMALA_RS27840 b61187d8566af35af4d2650e82a605e0 1012 SMART SM00304 397 467 8.4E-5 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMALA_RS27840 b61187d8566af35af4d2650e82a605e0 1012 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 582 689 1.1E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS27840 b61187d8566af35af4d2650e82a605e0 1012 SUPERFAMILY SSF55874 575 689 7.07E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS27840 b61187d8566af35af4d2650e82a605e0 1012 Pfam PF08376 Nitrate and nitrite sensing 99 358 3.3E-44 T 29-03-2018 IPR013587 Nitrate/nitrite sensing protein SMALA_RS27840 b61187d8566af35af4d2650e82a605e0 1012 Gene3D G3DSA:3.30.565.10 500 689 2.1E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS27840 b61187d8566af35af4d2650e82a605e0 1012 Pfam PF00672 HAMP domain 397 463 5.3E-8 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMALA_RS27840 b61187d8566af35af4d2650e82a605e0 1012 SMART SM00387 579 691 3.4E-9 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS25265 6084719f972b81df871cf75ef921855d 198 Gene3D G3DSA:3.20.19.10 1 171 1.6E-40 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel SMALA_RS25265 6084719f972b81df871cf75ef921855d 198 SUPERFAMILY SSF52016 3 191 6.28E-47 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel SMALA_RS25265 6084719f972b81df871cf75ef921855d 198 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 194 34.468 T 29-03-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 SMALA_RS25265 6084719f972b81df871cf75ef921855d 198 Pfam PF00694 Aconitase C-terminal domain 1 113 1.9E-22 T 29-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS25265 6084719f972b81df871cf75ef921855d 198 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 183 1.9E-49 T 29-03-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 SMALA_RS05640 20b31c5afe4376d5772993201d4a9e91 291 Pfam PF00582 Universal stress protein family 162 289 1.4E-22 T 29-03-2018 IPR006016 UspA GO:0006950 SMALA_RS05640 20b31c5afe4376d5772993201d4a9e91 291 Pfam PF00582 Universal stress protein family 9 149 9.5E-15 T 29-03-2018 IPR006016 UspA GO:0006950 SMALA_RS05640 20b31c5afe4376d5772993201d4a9e91 291 SUPERFAMILY SSF52402 162 289 9.21E-29 T 29-03-2018 SMALA_RS05640 20b31c5afe4376d5772993201d4a9e91 291 Gene3D G3DSA:3.40.50.620 5 153 9.7E-24 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS05640 20b31c5afe4376d5772993201d4a9e91 291 Gene3D G3DSA:3.40.50.620 156 291 1.2E-30 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS05640 20b31c5afe4376d5772993201d4a9e91 291 SUPERFAMILY SSF52402 9 153 1.34E-20 T 29-03-2018 SMALA_RS05640 20b31c5afe4376d5772993201d4a9e91 291 PRINTS PR01438 Universal stress protein signature 158 176 4.1E-11 T 29-03-2018 IPR006015 Universal stress protein A SMALA_RS05640 20b31c5afe4376d5772993201d4a9e91 291 PRINTS PR01438 Universal stress protein signature 267 289 4.1E-11 T 29-03-2018 IPR006015 Universal stress protein A SMALA_RS05640 20b31c5afe4376d5772993201d4a9e91 291 PRINTS PR01438 Universal stress protein signature 249 261 4.1E-11 T 29-03-2018 IPR006015 Universal stress protein A SMALA_RS40190 25ba4d289f78759c879f35f4ed6dc01c 251 SUPERFAMILY SSF51569 23 131 8.79E-6 T 29-03-2018 SMALA_RS40190 25ba4d289f78759c879f35f4ed6dc01c 251 Gene3D G3DSA:3.20.20.70 4 131 1.2E-4 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS40190 25ba4d289f78759c879f35f4ed6dc01c 251 Pfam PF04476 4-HFC-P synthase 3 232 6.7E-82 T 29-03-2018 IPR007565 (5-formylfuran-3-yl)methyl phosphate synthase KEGG: 00680+4.2.3.153|KEGG: 00902+4.2.3.15|MetaCyc: PWY-3041|MetaCyc: PWY-5254|MetaCyc: PWY-5423|MetaCyc: PWY-7410 SMALA_RS40190 25ba4d289f78759c879f35f4ed6dc01c 251 PIRSF PIRSF015957 1 245 4.4E-118 T 29-03-2018 IPR007565 (5-formylfuran-3-yl)methyl phosphate synthase KEGG: 00680+4.2.3.153|KEGG: 00902+4.2.3.15|MetaCyc: PWY-3041|MetaCyc: PWY-5254|MetaCyc: PWY-5423|MetaCyc: PWY-7410 SMALA_RS34790 148c80f44466d36598f16a39963b3e97 319 SUPERFAMILY SSF53187 56 318 1.94E-67 T 29-03-2018 SMALA_RS34790 148c80f44466d36598f16a39963b3e97 319 Gene3D G3DSA:3.40.630.10 41 319 5.1E-68 T 29-03-2018 SMALA_RS34790 148c80f44466d36598f16a39963b3e97 319 Pfam PF04389 Peptidase family M28 106 312 1.1E-45 T 29-03-2018 IPR007484 Peptidase M28 SMALA_RS43270 003a27a5fd1de717ebba68492964b8b7 239 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 69 6.1E-11 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM SMALA_RS43270 003a27a5fd1de717ebba68492964b8b7 239 Gene3D G3DSA:3.40.1620.10 1 72 5.8E-13 T 29-03-2018 SMALA_RS43270 003a27a5fd1de717ebba68492964b8b7 239 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 6 40 2.2E-8 T 29-03-2018 SMALA_RS43270 003a27a5fd1de717ebba68492964b8b7 239 SUPERFAMILY SSF143120 1 42 7.85E-8 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM SMALA_RS26175 e61c5a374ee35f61b9fcc4db2216f357 272 Gene3D G3DSA:3.90.1680.10 1 270 1.7E-79 T 29-03-2018 IPR003738 SOS response associated peptidase (SRAP) SMALA_RS26175 e61c5a374ee35f61b9fcc4db2216f357 272 Pfam PF02586 SOS response associated peptidase (SRAP) 1 251 2.9E-67 T 29-03-2018 IPR003738 SOS response associated peptidase (SRAP) SMALA_RS26175 e61c5a374ee35f61b9fcc4db2216f357 272 SUPERFAMILY SSF143081 2 262 1.31E-62 T 29-03-2018 IPR003738 SOS response associated peptidase (SRAP) SMALA_RS23880 f68612318d5ecff5e6b0e253087ec7cc 266 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 247 2.2E-61 T 29-03-2018 SMALA_RS23880 f68612318d5ecff5e6b0e253087ec7cc 266 Gene3D G3DSA:3.40.50.10090 2 47 2.9E-9 T 29-03-2018 SMALA_RS23880 f68612318d5ecff5e6b0e253087ec7cc 266 SUPERFAMILY SSF51735 8 248 6.67E-73 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS23880 f68612318d5ecff5e6b0e253087ec7cc 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 1.7E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS23880 f68612318d5ecff5e6b0e253087ec7cc 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 1.7E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS23880 f68612318d5ecff5e6b0e253087ec7cc 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 1.7E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS23880 f68612318d5ecff5e6b0e253087ec7cc 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 1.7E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS23880 f68612318d5ecff5e6b0e253087ec7cc 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 1.7E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS23880 f68612318d5ecff5e6b0e253087ec7cc 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.7E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS23880 f68612318d5ecff5e6b0e253087ec7cc 266 Gene3D G3DSA:3.40.50.720 48 258 1.7E-57 T 29-03-2018 SMALA_RS23880 f68612318d5ecff5e6b0e253087ec7cc 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 2.2E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS23880 f68612318d5ecff5e6b0e253087ec7cc 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 2.2E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS23880 f68612318d5ecff5e6b0e253087ec7cc 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 2.2E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS12985 19db1a8fcdc41435574d26a6252e2986 625 SUPERFAMILY SSF52540 18 225 2.48E-54 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS12985 19db1a8fcdc41435574d26a6252e2986 625 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 21 195 9.9E-19 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 SMALA_RS12985 19db1a8fcdc41435574d26a6252e2986 625 Gene3D G3DSA:3.30.70.870 308 387 2.0E-27 T 29-03-2018 SMALA_RS12985 19db1a8fcdc41435574d26a6252e2986 625 SUPERFAMILY SSF54980 418 513 2.73E-23 T 29-03-2018 IPR035647 EF-G domain III/V-like SMALA_RS12985 19db1a8fcdc41435574d26a6252e2986 625 SMART SM00838 417 501 0.0016 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like SMALA_RS12985 19db1a8fcdc41435574d26a6252e2986 625 Gene3D G3DSA:3.40.50.300 17 208 4.8E-36 T 29-03-2018 SMALA_RS12985 19db1a8fcdc41435574d26a6252e2986 625 SUPERFAMILY SSF50447 203 299 2.04E-16 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain SMALA_RS12985 19db1a8fcdc41435574d26a6252e2986 625 Gene3D G3DSA:3.30.70.240 413 568 9.0E-28 T 29-03-2018 SMALA_RS12985 19db1a8fcdc41435574d26a6252e2986 625 Pfam PF06421 GTP-binding protein LepA C-terminus 508 613 4.8E-49 T 29-03-2018 IPR013842 GTP-binding protein LepA, C-terminal SMALA_RS12985 19db1a8fcdc41435574d26a6252e2986 625 Hamap MF_00071 Elongation factor 4 [lepA]. 1 617 284.59 T 29-03-2018 IPR006297 Elongation factor 4 GO:0005525 SMALA_RS12985 19db1a8fcdc41435574d26a6252e2986 625 SUPERFAMILY SSF54980 311 390 6.12E-20 T 29-03-2018 IPR035647 EF-G domain III/V-like SMALA_RS12985 19db1a8fcdc41435574d26a6252e2986 625 PRINTS PR00315 GTP-binding elongation factor signature 64 72 4.2E-13 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMALA_RS12985 19db1a8fcdc41435574d26a6252e2986 625 PRINTS PR00315 GTP-binding elongation factor signature 146 155 4.2E-13 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMALA_RS12985 19db1a8fcdc41435574d26a6252e2986 625 PRINTS PR00315 GTP-binding elongation factor signature 94 104 4.2E-13 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMALA_RS12985 19db1a8fcdc41435574d26a6252e2986 625 PRINTS PR00315 GTP-binding elongation factor signature 110 121 4.2E-13 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMALA_RS12985 19db1a8fcdc41435574d26a6252e2986 625 PRINTS PR00315 GTP-binding elongation factor signature 21 34 4.2E-13 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMALA_RS12985 19db1a8fcdc41435574d26a6252e2986 625 TIGRFAM TIGR01393 lepA: elongation factor 4 19 615 2.6E-290 T 29-03-2018 IPR006297 Elongation factor 4 GO:0005525 SMALA_RS12985 19db1a8fcdc41435574d26a6252e2986 625 Gene3D G3DSA:2.40.30.10 209 307 1.6E-19 T 29-03-2018 SMALA_RS12985 19db1a8fcdc41435574d26a6252e2986 625 Pfam PF00679 Elongation factor G C-terminus 418 504 2.3E-20 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like SMALA_RS12985 19db1a8fcdc41435574d26a6252e2986 625 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 57 72 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site SMALA_RS12985 19db1a8fcdc41435574d26a6252e2986 625 Pfam PF00009 Elongation factor Tu GTP binding domain 19 201 7.3E-51 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMALA_RS19745 9b27cabbd571c72c25a0b4811fa93836 676 SUPERFAMILY SSF54211 255 428 9.67E-54 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SMALA_RS19745 9b27cabbd571c72c25a0b4811fa93836 676 Gene3D G3DSA:3.30.565.10 43 258 1.0E-73 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS19745 9b27cabbd571c72c25a0b4811fa93836 676 Gene3D G3DSA:3.40.50.670 437 673 2.0E-94 T 29-03-2018 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMALA_RS19745 9b27cabbd571c72c25a0b4811fa93836 676 Gene3D G3DSA:3.30.230.10 259 429 1.9E-58 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SMALA_RS19745 9b27cabbd571c72c25a0b4811fa93836 676 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 607 665 1.9E-24 T 29-03-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 SMALA_RS19745 9b27cabbd571c72c25a0b4811fa93836 676 PRINTS PR00418 DNA topoisomerase II family signature 140 154 5.3E-66 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMALA_RS19745 9b27cabbd571c72c25a0b4811fa93836 676 PRINTS PR00418 DNA topoisomerase II family signature 62 77 5.3E-66 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMALA_RS19745 9b27cabbd571c72c25a0b4811fa93836 676 PRINTS PR00418 DNA topoisomerase II family signature 541 558 5.3E-66 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMALA_RS19745 9b27cabbd571c72c25a0b4811fa93836 676 PRINTS PR00418 DNA topoisomerase II family signature 523 539 5.3E-66 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMALA_RS19745 9b27cabbd571c72c25a0b4811fa93836 676 PRINTS PR00418 DNA topoisomerase II family signature 608 624 5.3E-66 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMALA_RS19745 9b27cabbd571c72c25a0b4811fa93836 676 PRINTS PR00418 DNA topoisomerase II family signature 457 471 5.3E-66 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMALA_RS19745 9b27cabbd571c72c25a0b4811fa93836 676 PRINTS PR00418 DNA topoisomerase II family signature 561 573 5.3E-66 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMALA_RS19745 9b27cabbd571c72c25a0b4811fa93836 676 PRINTS PR00418 DNA topoisomerase II family signature 97 110 5.3E-66 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMALA_RS19745 9b27cabbd571c72c25a0b4811fa93836 676 PRINTS PR00418 DNA topoisomerase II family signature 305 318 5.3E-66 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMALA_RS19745 9b27cabbd571c72c25a0b4811fa93836 676 SUPERFAMILY SSF55874 33 238 7.67E-69 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS19745 9b27cabbd571c72c25a0b4811fa93836 676 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 30 676 88.515 T 29-03-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 SMALA_RS19745 9b27cabbd571c72c25a0b4811fa93836 676 ProSitePatterns PS00177 DNA topoisomerase II signature. 459 467 - T 29-03-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMALA_RS19745 9b27cabbd571c72c25a0b4811fa93836 676 SMART SM00387 58 202 2.6E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS19745 9b27cabbd571c72c25a0b4811fa93836 676 SMART SM00433 62 669 0.0 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMALA_RS19745 9b27cabbd571c72c25a0b4811fa93836 676 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 60 200 1.7E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS19745 9b27cabbd571c72c25a0b4811fa93836 676 Pfam PF01751 Toprim domain 456 566 1.9E-16 T 29-03-2018 IPR006171 TOPRIM domain SMALA_RS19745 9b27cabbd571c72c25a0b4811fa93836 676 PRINTS PR01159 DNA gyrase subunit B signature 507 516 1.5E-74 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SMALA_RS19745 9b27cabbd571c72c25a0b4811fa93836 676 PRINTS PR01159 DNA gyrase subunit B signature 222 235 1.5E-74 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SMALA_RS19745 9b27cabbd571c72c25a0b4811fa93836 676 PRINTS PR01159 DNA gyrase subunit B signature 629 641 1.5E-74 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SMALA_RS19745 9b27cabbd571c72c25a0b4811fa93836 676 PRINTS PR01159 DNA gyrase subunit B signature 207 222 1.5E-74 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SMALA_RS19745 9b27cabbd571c72c25a0b4811fa93836 676 PRINTS PR01159 DNA gyrase subunit B signature 411 431 1.5E-74 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SMALA_RS19745 9b27cabbd571c72c25a0b4811fa93836 676 PRINTS PR01159 DNA gyrase subunit B signature 254 276 1.5E-74 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SMALA_RS19745 9b27cabbd571c72c25a0b4811fa93836 676 PRINTS PR01159 DNA gyrase subunit B signature 279 297 1.5E-74 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SMALA_RS19745 9b27cabbd571c72c25a0b4811fa93836 676 PRINTS PR01159 DNA gyrase subunit B signature 397 411 1.5E-74 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SMALA_RS19745 9b27cabbd571c72c25a0b4811fa93836 676 PRINTS PR01159 DNA gyrase subunit B signature 33 43 1.5E-74 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SMALA_RS19745 9b27cabbd571c72c25a0b4811fa93836 676 PRINTS PR01159 DNA gyrase subunit B signature 349 365 1.5E-74 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SMALA_RS19745 9b27cabbd571c72c25a0b4811fa93836 676 PRINTS PR01159 DNA gyrase subunit B signature 645 661 1.5E-74 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SMALA_RS19745 9b27cabbd571c72c25a0b4811fa93836 676 SUPERFAMILY SSF56719 431 671 3.4E-82 T 29-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 SMALA_RS19745 9b27cabbd571c72c25a0b4811fa93836 676 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 33 676 2.7E-284 T 29-03-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 SMALA_RS19745 9b27cabbd571c72c25a0b4811fa93836 676 Pfam PF00204 DNA gyrase B 255 427 1.2E-60 T 29-03-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMALA_RS23785 1d43ebfd7a83f0bc2c11d2e5bc1d3417 166 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 70 86 2.2E-11 T 29-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 SMALA_RS23785 1d43ebfd7a83f0bc2c11d2e5bc1d3417 166 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 46 62 2.2E-11 T 29-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 SMALA_RS23785 1d43ebfd7a83f0bc2c11d2e5bc1d3417 166 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 141 159 2.2E-11 T 29-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 SMALA_RS23785 1d43ebfd7a83f0bc2c11d2e5bc1d3417 166 Pfam PF00210 Ferritin-like domain 27 161 2.9E-22 T 29-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 SMALA_RS23785 1d43ebfd7a83f0bc2c11d2e5bc1d3417 166 ProSitePatterns PS00818 Dps protein family signature 1. 46 62 - T 29-03-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 SMALA_RS23785 1d43ebfd7a83f0bc2c11d2e5bc1d3417 166 Gene3D G3DSA:1.20.1260.10 16 166 1.9E-38 T 29-03-2018 IPR012347 Ferritin-related SMALA_RS23785 1d43ebfd7a83f0bc2c11d2e5bc1d3417 166 SUPERFAMILY SSF47240 18 161 3.29E-44 T 29-03-2018 IPR009078 Ferritin-like superfamily SMALA_RS23785 1d43ebfd7a83f0bc2c11d2e5bc1d3417 166 PIRSF PIRSF005900 15 166 9.1E-40 T 29-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 SMALA_RS38070 7906a544cfad4ed313a5683eca15efcf 497 PIRSF PIRSF002744 1 483 1.3E-102 T 29-03-2018 IPR026030 Purine-cytosine permease Fcy2/21/22 GO:0005215|GO:0016021|GO:0055085 SMALA_RS38070 7906a544cfad4ed313a5683eca15efcf 497 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 19 431 2.1E-54 T 29-03-2018 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 SMALA_RS19075 5929e5dbdc64ff5df68d5243d47060f8 162 PRINTS PR00598 Bacterial regulatory protein MarR family signature 115 135 1.2E-7 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS19075 5929e5dbdc64ff5df68d5243d47060f8 162 PRINTS PR00598 Bacterial regulatory protein MarR family signature 49 65 1.2E-7 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS19075 5929e5dbdc64ff5df68d5243d47060f8 162 PRINTS PR00598 Bacterial regulatory protein MarR family signature 85 101 1.2E-7 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS19075 5929e5dbdc64ff5df68d5243d47060f8 162 PRINTS PR00598 Bacterial regulatory protein MarR family signature 66 81 1.2E-7 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS19075 5929e5dbdc64ff5df68d5243d47060f8 162 SMART SM00347 25 125 6.6E-8 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS19075 5929e5dbdc64ff5df68d5243d47060f8 162 SUPERFAMILY SSF46785 35 139 6.59E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS19075 5929e5dbdc64ff5df68d5243d47060f8 162 Gene3D G3DSA:1.10.10.10 2 160 1.5E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS19075 5929e5dbdc64ff5df68d5243d47060f8 162 Pfam PF01047 MarR family 37 89 1.8E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS01795 56be570d17b0739fcf3ea252e9091a2d 409 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 351 360 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMALA_RS01795 56be570d17b0739fcf3ea252e9091a2d 409 SUPERFAMILY SSF48264 25 409 7.07E-86 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS01795 56be570d17b0739fcf3ea252e9091a2d 409 Pfam PF00067 Cytochrome P450 228 376 3.7E-19 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS01795 56be570d17b0739fcf3ea252e9091a2d 409 Gene3D G3DSA:1.10.630.10 8 409 2.9E-64 T 29-03-2018 SMALA_RS01795 56be570d17b0739fcf3ea252e9091a2d 409 PRINTS PR00385 P450 superfamily signature 282 293 1.8E-7 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS01795 56be570d17b0739fcf3ea252e9091a2d 409 PRINTS PR00385 P450 superfamily signature 349 358 1.8E-7 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS01795 56be570d17b0739fcf3ea252e9091a2d 409 PRINTS PR00385 P450 superfamily signature 358 369 1.8E-7 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS01795 56be570d17b0739fcf3ea252e9091a2d 409 PRINTS PR00385 P450 superfamily signature 245 262 1.8E-7 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS01795 56be570d17b0739fcf3ea252e9091a2d 409 PRINTS PR00359 B-class P450 signature 358 369 2.4E-56 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS01795 56be570d17b0739fcf3ea252e9091a2d 409 PRINTS PR00359 B-class P450 signature 282 293 2.4E-56 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS01795 56be570d17b0739fcf3ea252e9091a2d 409 PRINTS PR00359 B-class P450 signature 99 110 2.4E-56 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS01795 56be570d17b0739fcf3ea252e9091a2d 409 PRINTS PR00359 B-class P450 signature 328 343 2.4E-56 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS01795 56be570d17b0739fcf3ea252e9091a2d 409 PRINTS PR00359 B-class P450 signature 200 222 2.4E-56 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS01795 56be570d17b0739fcf3ea252e9091a2d 409 PRINTS PR00359 B-class P450 signature 163 178 2.4E-56 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS01795 56be570d17b0739fcf3ea252e9091a2d 409 PRINTS PR00359 B-class P450 signature 300 327 2.4E-56 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS01795 56be570d17b0739fcf3ea252e9091a2d 409 PRINTS PR00359 B-class P450 signature 146 162 2.4E-56 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS01795 56be570d17b0739fcf3ea252e9091a2d 409 PRINTS PR00359 B-class P450 signature 349 358 2.4E-56 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS23765 465797608ccd1c926414a33859e812a1 192 SUPERFAMILY SSF53218 9 159 2.88E-40 T 29-03-2018 IPR001453 MoaB/Mog domain SMALA_RS23765 465797608ccd1c926414a33859e812a1 192 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 10 147 4.1E-31 T 29-03-2018 IPR001453 MoaB/Mog domain SMALA_RS23765 465797608ccd1c926414a33859e812a1 192 SMART SM00852 12 154 3.1E-24 T 29-03-2018 IPR001453 MoaB/Mog domain SMALA_RS23765 465797608ccd1c926414a33859e812a1 192 Pfam PF00994 Probable molybdopterin binding domain 13 153 2.2E-28 T 29-03-2018 IPR001453 MoaB/Mog domain SMALA_RS23765 465797608ccd1c926414a33859e812a1 192 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 70 83 - T 29-03-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 SMALA_RS23765 465797608ccd1c926414a33859e812a1 192 Gene3D G3DSA:3.40.980.10 5 165 2.1E-37 T 29-03-2018 IPR001453 MoaB/Mog domain SMALA_RS10600 d4effc256ae62a4c8f01203812a3df59 225 Gene3D G3DSA:1.10.10.10 130 225 4.0E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS10600 d4effc256ae62a4c8f01203812a3df59 225 Pfam PF00072 Response regulator receiver domain 5 119 2.6E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS10600 d4effc256ae62a4c8f01203812a3df59 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 175 191 1.1E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS10600 d4effc256ae62a4c8f01203812a3df59 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 161 175 1.1E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS10600 d4effc256ae62a4c8f01203812a3df59 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 191 203 1.1E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS10600 d4effc256ae62a4c8f01203812a3df59 225 Gene3D G3DSA:3.40.50.2300 2 129 1.1E-32 T 29-03-2018 SMALA_RS10600 d4effc256ae62a4c8f01203812a3df59 225 SUPERFAMILY SSF46894 154 221 6.8E-21 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS10600 d4effc256ae62a4c8f01203812a3df59 225 SMART SM00421 158 215 5.5E-24 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS10600 d4effc256ae62a4c8f01203812a3df59 225 SMART SM00448 3 118 3.2E-29 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS10600 d4effc256ae62a4c8f01203812a3df59 225 Pfam PF00196 Bacterial regulatory proteins, luxR family 160 215 9.5E-17 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS10600 d4effc256ae62a4c8f01203812a3df59 225 ProSitePatterns PS00622 LuxR-type HTH domain signature. 175 202 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS10600 d4effc256ae62a4c8f01203812a3df59 225 SUPERFAMILY SSF52172 3 129 3.13E-32 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS07445 9bbbfeac5a1bcbd0f6028b220047224e 326 Gene3D G3DSA:3.20.20.100 1 326 5.1E-85 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS07445 9bbbfeac5a1bcbd0f6028b220047224e 326 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 135 152 - T 29-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 SMALA_RS07445 9bbbfeac5a1bcbd0f6028b220047224e 326 Pfam PF00248 Aldo/keto reductase family 15 311 4.5E-61 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS07445 9bbbfeac5a1bcbd0f6028b220047224e 326 PRINTS PR00069 Aldo-keto reductase signature 104 122 5.6E-5 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMALA_RS07445 9bbbfeac5a1bcbd0f6028b220047224e 326 PRINTS PR00069 Aldo-keto reductase signature 135 152 5.6E-5 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMALA_RS07445 9bbbfeac5a1bcbd0f6028b220047224e 326 SUPERFAMILY SSF51430 1 315 1.44E-89 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS40165 278b6edc77bb70afde419b7e484120e4 278 Pfam PF04672 S-adenosyl methyltransferase 10 278 2.3E-115 T 29-03-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type SMALA_RS40165 278b6edc77bb70afde419b7e484120e4 278 SUPERFAMILY SSF53335 16 252 1.2E-44 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS40165 278b6edc77bb70afde419b7e484120e4 278 PIRSF PIRSF017393 2 278 1.3E-102 T 29-03-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type SMALA_RS40165 278b6edc77bb70afde419b7e484120e4 278 Gene3D G3DSA:3.40.50.150 2 278 2.5E-53 T 29-03-2018 SMALA_RS02170 74cf469fc6cbb20b6a0b539581b0c5ea 378 Gene3D G3DSA:3.40.50.1820 1 293 1.2E-67 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS02170 74cf469fc6cbb20b6a0b539581b0c5ea 378 Gene3D G3DSA:3.40.50.1820 294 377 7.0E-9 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS02170 74cf469fc6cbb20b6a0b539581b0c5ea 378 SUPERFAMILY SSF53474 4 373 4.33E-77 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS02170 74cf469fc6cbb20b6a0b539581b0c5ea 378 Pfam PF00135 Carboxylesterase family 4 224 3.9E-61 T 29-03-2018 IPR002018 Carboxylesterase, type B SMALA_RS05335 1b9b5686286f50fe4499902173d00409 783 SUPERFAMILY SSF52518 412 623 2.47E-46 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold SMALA_RS05335 1b9b5686286f50fe4499902173d00409 783 SUPERFAMILY SSF52518 21 371 4.21E-61 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold SMALA_RS05335 1b9b5686286f50fe4499902173d00409 783 SMART SM00861 419 623 1.9E-10 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain SMALA_RS05335 1b9b5686286f50fe4499902173d00409 783 SUPERFAMILY SSF52922 638 782 4.32E-25 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMALA_RS05335 1b9b5686286f50fe4499902173d00409 783 Gene3D G3DSA:3.40.50.920 643 783 2.6E-27 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMALA_RS05335 1b9b5686286f50fe4499902173d00409 783 Gene3D G3DSA:3.40.50.970 407 632 6.8E-41 T 29-03-2018 SMALA_RS05335 1b9b5686286f50fe4499902173d00409 783 Gene3D G3DSA:3.40.50.970 15 406 2.0E-50 T 29-03-2018 SMALA_RS05335 1b9b5686286f50fe4499902173d00409 783 PIRSF PIRSF000156 20 783 2.7E-64 T 29-03-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 SMALA_RS05335 1b9b5686286f50fe4499902173d00409 783 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 66 242 7.0E-9 T 29-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SMALA_RS34045 bfe3fd9f01465736fceb6e3771cf2deb 1073 Gene3D G3DSA:3.40.50.300 164 485 1.0E-6 T 29-03-2018 SMALA_RS34045 bfe3fd9f01465736fceb6e3771cf2deb 1073 Pfam PF05729 NACHT domain 281 444 1.5E-27 T 29-03-2018 SMALA_RS34045 bfe3fd9f01465736fceb6e3771cf2deb 1073 SUPERFAMILY SSF52047 937 1044 1.02E-14 T 29-03-2018 SMALA_RS34045 bfe3fd9f01465736fceb6e3771cf2deb 1073 SUPERFAMILY SSF52047 817 908 1.02E-14 T 29-03-2018 SMALA_RS34045 bfe3fd9f01465736fceb6e3771cf2deb 1073 Gene3D G3DSA:3.80.10.10 913 1065 8.1E-9 T 29-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like SMALA_RS34045 bfe3fd9f01465736fceb6e3771cf2deb 1073 Gene3D G3DSA:3.80.10.10 795 912 8.7E-10 T 29-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like SMALA_RS34045 bfe3fd9f01465736fceb6e3771cf2deb 1073 SUPERFAMILY SSF52540 279 411 4.28E-8 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS39675 75010f09dc546560ea182fafe4461bbe 527 Gene3D G3DSA:3.90.76.10 56 188 1.3E-17 T 29-03-2018 SMALA_RS39675 75010f09dc546560ea182fafe4461bbe 527 Gene3D G3DSA:3.40.190.10 189 286 1.1E-23 T 29-03-2018 SMALA_RS39675 75010f09dc546560ea182fafe4461bbe 527 PIRSF PIRSF002741 10 524 4.6E-56 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 SMALA_RS39675 75010f09dc546560ea182fafe4461bbe 527 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 87 438 3.2E-60 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain SMALA_RS39675 75010f09dc546560ea182fafe4461bbe 527 SUPERFAMILY SSF53850 41 523 8.32E-91 T 29-03-2018 SMALA_RS39675 75010f09dc546560ea182fafe4461bbe 527 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 11 31 5.3E-4 T 29-03-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal SMALA_RS39675 75010f09dc546560ea182fafe4461bbe 527 Gene3D G3DSA:3.10.105.10 287 496 5.6E-33 T 29-03-2018 SMALA_RS30170 46261b70559b4d923c56c7c7130c7ef6 315 SUPERFAMILY SSF161098 83 303 1.57E-57 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS30170 46261b70559b4d923c56c7c7130c7ef6 315 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 307 3.2E-24 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS30170 46261b70559b4d923c56c7c7130c7ef6 315 Gene3D G3DSA:1.10.3720.10 88 310 9.5E-45 T 29-03-2018 SMALA_RS30170 46261b70559b4d923c56c7c7130c7ef6 315 Gene3D G3DSA:1.20.58.370 25 68 7.8E-5 T 29-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain SMALA_RS08745 2984450ba1a4ec50e66881ed6866bd8b 573 Pfam PF02463 RecF/RecN/SMC N terminal domain 12 526 7.3E-16 T 29-03-2018 IPR003395 RecF/RecN/SMC, N-terminal SMALA_RS08745 2984450ba1a4ec50e66881ed6866bd8b 573 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 568 2.0E-162 T 29-03-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 SMALA_RS08745 2984450ba1a4ec50e66881ed6866bd8b 573 PIRSF PIRSF003128 1 571 1.7E-157 T 29-03-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 SMALA_RS08745 2984450ba1a4ec50e66881ed6866bd8b 573 SUPERFAMILY SSF52540 7 46 3.23E-24 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS08745 2984450ba1a4ec50e66881ed6866bd8b 573 SUPERFAMILY SSF52540 385 522 3.23E-24 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS08745 2984450ba1a4ec50e66881ed6866bd8b 573 Gene3D G3DSA:3.40.50.300 1 548 6.8E-38 T 29-03-2018 SMALA_RS08745 2984450ba1a4ec50e66881ed6866bd8b 573 SUPERFAMILY SSF52540 2 216 3.96E-54 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS29595 856b123e3e76d727390cc10bc3c87a6d 307 TIGRFAM TIGR03560 F420_Rv1855c: probable F420-dependent oxidoreductase, Rv1855c family 2 228 1.3E-90 T 29-03-2018 IPR019952 F420-dependent oxidoreductase-predicted, Rv1855c SMALA_RS29595 856b123e3e76d727390cc10bc3c87a6d 307 Pfam PF00296 Luciferase-like monooxygenase 8 248 4.8E-51 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS29595 856b123e3e76d727390cc10bc3c87a6d 307 Gene3D G3DSA:3.20.20.30 2 307 8.1E-73 T 29-03-2018 SMALA_RS29595 856b123e3e76d727390cc10bc3c87a6d 307 SUPERFAMILY SSF51679 4 303 5.76E-68 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS02540 d2aa78f2e055ac5ef70b1a9dfbc7d64b 1176 SMART SM00481 6 73 4.4E-28 T 29-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal SMALA_RS02540 d2aa78f2e055ac5ef70b1a9dfbc7d64b 1176 Pfam PF14579 Helix-hairpin-helix motif 828 916 1.0E-22 T 29-03-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMALA_RS02540 d2aa78f2e055ac5ef70b1a9dfbc7d64b 1176 Pfam PF02811 PHP domain 7 193 2.2E-44 T 29-03-2018 IPR004013 PHP domain GO:0003824 SMALA_RS02540 d2aa78f2e055ac5ef70b1a9dfbc7d64b 1176 Gene3D G3DSA:1.10.150.280 806 914 3.5E-7 T 29-03-2018 SMALA_RS02540 d2aa78f2e055ac5ef70b1a9dfbc7d64b 1176 SUPERFAMILY SSF89550 6 247 3.27E-29 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 SMALA_RS02540 d2aa78f2e055ac5ef70b1a9dfbc7d64b 1176 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 315 754 1.5E-159 T 29-03-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMALA_RS02540 d2aa78f2e055ac5ef70b1a9dfbc7d64b 1176 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 5 1058 0.0 T 29-03-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMALA_RS02540 d2aa78f2e055ac5ef70b1a9dfbc7d64b 1176 Gene3D G3DSA:2.40.50.140 1005 1095 7.4E-12 T 29-03-2018 SMALA_RS02540 d2aa78f2e055ac5ef70b1a9dfbc7d64b 1176 Gene3D G3DSA:3.20.20.140 2 265 9.8E-45 T 29-03-2018 SMALA_RS19575 4ffc663cab710c493b36e79c3661076a 78 SUPERFAMILY SSF46911 5 75 1.44E-28 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS19575 4ffc663cab710c493b36e79c3661076a 78 ProSitePatterns PS00057 Ribosomal protein S18 signature. 24 47 - T 29-03-2018 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS19575 4ffc663cab710c493b36e79c3661076a 78 Gene3D G3DSA:4.10.640.10 1 78 9.6E-33 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS19575 4ffc663cab710c493b36e79c3661076a 78 TIGRFAM TIGR00165 S18: ribosomal protein bS18 9 75 3.5E-30 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS19575 4ffc663cab710c493b36e79c3661076a 78 PRINTS PR00974 Ribosomal protein S18 family signature 63 73 4.8E-16 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS19575 4ffc663cab710c493b36e79c3661076a 78 PRINTS PR00974 Ribosomal protein S18 family signature 31 41 4.8E-16 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS19575 4ffc663cab710c493b36e79c3661076a 78 PRINTS PR00974 Ribosomal protein S18 family signature 41 48 4.8E-16 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS19575 4ffc663cab710c493b36e79c3661076a 78 PRINTS PR00974 Ribosomal protein S18 family signature 49 63 4.8E-16 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS19575 4ffc663cab710c493b36e79c3661076a 78 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 3 76 20.759 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS19575 4ffc663cab710c493b36e79c3661076a 78 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 23 73 6.0E-24 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS19575 4ffc663cab710c493b36e79c3661076a 78 Pfam PF01084 Ribosomal protein S18 21 71 4.8E-24 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS13300 0b0b7475d0b98868955ec78be0d9d969 360 SMART SM00418 278 356 7.0E-20 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS13300 0b0b7475d0b98868955ec78be0d9d969 360 SUPERFAMILY SSF46785 278 349 8.88E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS13300 0b0b7475d0b98868955ec78be0d9d969 360 Gene3D G3DSA:1.10.10.10 263 360 4.9E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS13300 0b0b7475d0b98868955ec78be0d9d969 360 Pfam PF12840 Helix-turn-helix domain 280 335 1.3E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS13300 0b0b7475d0b98868955ec78be0d9d969 360 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 312 327 2.0E-9 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS13300 0b0b7475d0b98868955ec78be0d9d969 360 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 327 342 2.0E-9 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS13300 0b0b7475d0b98868955ec78be0d9d969 360 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 280 295 2.0E-9 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS26825 a5a5eada8794a1b4a9b23e0f1ef5de55 430 Pfam PF00742 Homoserine dehydrogenase 139 319 2.2E-67 T 29-03-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 SMALA_RS26825 a5a5eada8794a1b4a9b23e0f1ef5de55 430 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 13 131 7.7E-20 T 29-03-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 SMALA_RS26825 a5a5eada8794a1b4a9b23e0f1ef5de55 430 SUPERFAMILY SSF55021 350 422 4.58E-15 T 29-03-2018 SMALA_RS26825 a5a5eada8794a1b4a9b23e0f1ef5de55 430 Gene3D G3DSA:3.30.360.10 160 302 3.2E-53 T 29-03-2018 SMALA_RS26825 a5a5eada8794a1b4a9b23e0f1ef5de55 430 Pfam PF01842 ACT domain 354 415 2.8E-13 T 29-03-2018 IPR002912 ACT domain SMALA_RS26825 a5a5eada8794a1b4a9b23e0f1ef5de55 430 PIRSF PIRSF000098 4 430 1.2E-156 T 29-03-2018 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 SMALA_RS26825 a5a5eada8794a1b4a9b23e0f1ef5de55 430 SUPERFAMILY SSF55347 139 306 1.96E-53 T 29-03-2018 SMALA_RS26825 a5a5eada8794a1b4a9b23e0f1ef5de55 430 Gene3D G3DSA:3.40.50.720 3 159 8.0E-30 T 29-03-2018 SMALA_RS26825 a5a5eada8794a1b4a9b23e0f1ef5de55 430 Gene3D G3DSA:3.30.70.260 348 426 1.2E-22 T 29-03-2018 SMALA_RS26825 a5a5eada8794a1b4a9b23e0f1ef5de55 430 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 185 207 - T 29-03-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 SMALA_RS26825 a5a5eada8794a1b4a9b23e0f1ef5de55 430 SUPERFAMILY SSF51735 5 160 1.97E-31 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS40835 17c65e8e353d675122d6a5221003bd98 254 Gene3D G3DSA:3.40.50.300 3 244 5.9E-63 T 29-03-2018 SMALA_RS40835 17c65e8e353d675122d6a5221003bd98 254 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS40835 17c65e8e353d675122d6a5221003bd98 254 SUPERFAMILY SSF52540 6 230 3.52E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS40835 17c65e8e353d675122d6a5221003bd98 254 SMART SM00382 31 229 4.7E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS40835 17c65e8e353d675122d6a5221003bd98 254 Pfam PF00005 ABC transporter 22 172 8.1E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS09530 a1ee331cd038889d764853d0b1af6002 372 ProSitePatterns PS01054 Transaldolase signature 1. 41 49 - T 29-03-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 SMALA_RS09530 a1ee331cd038889d764853d0b1af6002 372 Hamap MF_00493 Transaldolase [tal]. 1 370 163.488 T 29-03-2018 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 SMALA_RS09530 a1ee331cd038889d764853d0b1af6002 372 Gene3D G3DSA:3.20.20.70 1 361 8.7E-132 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS09530 a1ee331cd038889d764853d0b1af6002 372 TIGRFAM TIGR00876 tal_mycobact: transaldolase 12 359 8.4E-135 T 29-03-2018 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 SMALA_RS09530 a1ee331cd038889d764853d0b1af6002 372 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 15 359 9.7E-85 T 29-03-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 SMALA_RS09530 a1ee331cd038889d764853d0b1af6002 372 PIRSF PIRSF036915 1 372 1.2E-177 T 29-03-2018 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 SMALA_RS09530 a1ee331cd038889d764853d0b1af6002 372 SUPERFAMILY SSF51569 4 359 2.08E-78 T 29-03-2018 SMALA_RS06080 f53fa2856503a77e8cdbfd6d4cdf537d 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 1.0E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS06080 f53fa2856503a77e8cdbfd6d4cdf537d 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 1.0E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS06080 f53fa2856503a77e8cdbfd6d4cdf537d 195 SUPERFAMILY SSF46689 5 84 1.44E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS06080 f53fa2856503a77e8cdbfd6d4cdf537d 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 63 1.2E-13 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS06080 f53fa2856503a77e8cdbfd6d4cdf537d 195 SUPERFAMILY SSF48498 80 193 2.45E-16 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS06080 f53fa2856503a77e8cdbfd6d4cdf537d 195 Gene3D G3DSA:1.10.357.10 7 195 1.5E-28 T 29-03-2018 SMALA_RS29680 b8049416ec023f020349a74a5be050f6 696 Gene3D G3DSA:2.60.40.1180 599 696 1.7E-12 T 29-03-2018 SMALA_RS29680 b8049416ec023f020349a74a5be050f6 696 SUPERFAMILY SSF51445 291 624 3.04E-81 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS29680 b8049416ec023f020349a74a5be050f6 696 PIRSF PIRSF005536 77 696 3.1E-150 T 29-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 SMALA_RS29680 b8049416ec023f020349a74a5be050f6 696 Pfam PF16874 Glycosyl hydrolase family 36 C-terminal domain 643 693 3.0E-10 T 29-03-2018 IPR031705 Glycosyl hydrolase family 36, C-terminal KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 SMALA_RS29680 b8049416ec023f020349a74a5be050f6 696 Gene3D G3DSA:3.20.20.70 278 598 5.5E-48 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS29680 b8049416ec023f020349a74a5be050f6 696 Pfam PF16875 Glycosyl hydrolase family 36 N-terminal domain 97 247 6.3E-29 T 29-03-2018 IPR031704 Glycosyl hydrolase family 36, N-terminal KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 SMALA_RS29680 b8049416ec023f020349a74a5be050f6 696 PRINTS PR00743 Glycosyl hydrolase family 36 signature 374 396 1.4E-42 T 29-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 SMALA_RS29680 b8049416ec023f020349a74a5be050f6 696 PRINTS PR00743 Glycosyl hydrolase family 36 signature 296 310 1.4E-42 T 29-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 SMALA_RS29680 b8049416ec023f020349a74a5be050f6 696 PRINTS PR00743 Glycosyl hydrolase family 36 signature 432 447 1.4E-42 T 29-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 SMALA_RS29680 b8049416ec023f020349a74a5be050f6 696 PRINTS PR00743 Glycosyl hydrolase family 36 signature 511 527 1.4E-42 T 29-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 SMALA_RS29680 b8049416ec023f020349a74a5be050f6 696 PRINTS PR00743 Glycosyl hydrolase family 36 signature 324 339 1.4E-42 T 29-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 SMALA_RS29680 b8049416ec023f020349a74a5be050f6 696 PRINTS PR00743 Glycosyl hydrolase family 36 signature 260 280 1.4E-42 T 29-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 SMALA_RS29680 b8049416ec023f020349a74a5be050f6 696 PRINTS PR00743 Glycosyl hydrolase family 36 signature 486 502 1.4E-42 T 29-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 SMALA_RS29680 b8049416ec023f020349a74a5be050f6 696 PRINTS PR00743 Glycosyl hydrolase family 36 signature 209 224 1.4E-42 T 29-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 SMALA_RS29680 b8049416ec023f020349a74a5be050f6 696 Gene3D G3DSA:2.70.98.60 1 277 3.5E-55 T 29-03-2018 SMALA_RS29680 b8049416ec023f020349a74a5be050f6 696 Pfam PF02065 Melibiase 257 601 3.5E-95 T 29-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 SMALA_RS33470 04758cf398454ceb8ff24a341db21919 319 Pfam PF00005 ABC transporter 18 156 2.4E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS33470 04758cf398454ceb8ff24a341db21919 319 SMART SM00382 26 204 2.0E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS33470 04758cf398454ceb8ff24a341db21919 319 Gene3D G3DSA:3.40.50.300 1 273 7.7E-57 T 29-03-2018 SMALA_RS33470 04758cf398454ceb8ff24a341db21919 319 SUPERFAMILY SSF52540 2 220 4.6E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS16065 4824e387f89d4bb4b3b2b995a3e38ec3 451 PRINTS PR01181 Diaminopimelate decarboxylase signature 403 425 2.7E-5 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMALA_RS16065 4824e387f89d4bb4b3b2b995a3e38ec3 451 PRINTS PR01181 Diaminopimelate decarboxylase signature 83 100 2.7E-5 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMALA_RS16065 4824e387f89d4bb4b3b2b995a3e38ec3 451 PRINTS PR01181 Diaminopimelate decarboxylase signature 172 181 2.7E-5 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMALA_RS16065 4824e387f89d4bb4b3b2b995a3e38ec3 451 Gene3D G3DSA:2.40.37.10 289 447 1.1E-30 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 SMALA_RS16065 4824e387f89d4bb4b3b2b995a3e38ec3 451 Gene3D G3DSA:3.20.20.10 38 288 2.3E-47 T 29-03-2018 IPR029066 PLP-binding barrel SMALA_RS16065 4824e387f89d4bb4b3b2b995a3e38ec3 451 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 199 212 2.3E-11 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMALA_RS16065 4824e387f89d4bb4b3b2b995a3e38ec3 451 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 285 304 2.3E-11 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMALA_RS16065 4824e387f89d4bb4b3b2b995a3e38ec3 451 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 393 406 2.3E-11 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMALA_RS16065 4824e387f89d4bb4b3b2b995a3e38ec3 451 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 65 83 2.3E-11 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMALA_RS16065 4824e387f89d4bb4b3b2b995a3e38ec3 451 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 85 97 2.3E-11 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMALA_RS16065 4824e387f89d4bb4b3b2b995a3e38ec3 451 SUPERFAMILY SSF50621 265 412 1.67E-31 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 SMALA_RS16065 4824e387f89d4bb4b3b2b995a3e38ec3 451 SUPERFAMILY SSF51419 35 296 1.11E-52 T 29-03-2018 IPR029066 PLP-binding barrel SMALA_RS16065 4824e387f89d4bb4b3b2b995a3e38ec3 451 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 236 252 - T 29-03-2018 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site SMALA_RS16065 4824e387f89d4bb4b3b2b995a3e38ec3 451 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 280 393 1.7E-9 T 29-03-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 SMALA_RS16065 4824e387f89d4bb4b3b2b995a3e38ec3 451 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 60 294 1.2E-37 T 29-03-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 SMALA_RS29985 9a1924eda9292f639bc9370b301f18ee 304 Pfam PF13578 Methyltransferase domain 48 168 3.8E-13 T 29-03-2018 SMALA_RS29985 9a1924eda9292f639bc9370b301f18ee 304 Gene3D G3DSA:3.40.50.150 16 187 8.2E-8 T 29-03-2018 SMALA_RS29985 9a1924eda9292f639bc9370b301f18ee 304 SUPERFAMILY SSF53335 43 174 3.99E-7 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS23850 1402677cf52890b73c3bb3c7299b149c 202 Pfam PF16859 Bacterial transcriptional repressor C-terminal 85 195 2.8E-31 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS23850 1402677cf52890b73c3bb3c7299b149c 202 SUPERFAMILY SSF48498 85 200 4.11E-28 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS23850 1402677cf52890b73c3bb3c7299b149c 202 Gene3D G3DSA:1.10.10.60 7 56 8.7E-12 T 29-03-2018 SMALA_RS23850 1402677cf52890b73c3bb3c7299b149c 202 ProSitePatterns PS01081 TetR-type HTH domain signature. 39 69 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site SMALA_RS23850 1402677cf52890b73c3bb3c7299b149c 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 32 72 1.1E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS23850 1402677cf52890b73c3bb3c7299b149c 202 Gene3D G3DSA:1.10.357.10 57 202 2.9E-23 T 29-03-2018 SMALA_RS23850 1402677cf52890b73c3bb3c7299b149c 202 SUPERFAMILY SSF46689 24 82 2.64E-10 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS10350 1b684379b698b356c89b016c2f167a5b 302 Hamap MF_00443 Thiazole synthase [thiG]. 42 293 42.529 T 29-03-2018 IPR008867 Thiazole synthase GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 SMALA_RS10350 1b684379b698b356c89b016c2f167a5b 302 Pfam PF05690 Thiazole biosynthesis protein ThiG 45 287 6.3E-105 T 29-03-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 SMALA_RS10350 1b684379b698b356c89b016c2f167a5b 302 Gene3D G3DSA:3.20.20.70 40 299 1.6E-51 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS10350 1b684379b698b356c89b016c2f167a5b 302 SUPERFAMILY SSF110399 41 279 1.7E-80 T 29-03-2018 SMALA_RS36730 6e1532bf47f004ac9a75e8d84c2bbb81 419 PRINTS PR00359 B-class P450 signature 295 306 7.2E-41 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS36730 6e1532bf47f004ac9a75e8d84c2bbb81 419 PRINTS PR00359 B-class P450 signature 150 166 7.2E-41 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS36730 6e1532bf47f004ac9a75e8d84c2bbb81 419 PRINTS PR00359 B-class P450 signature 312 339 7.2E-41 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS36730 6e1532bf47f004ac9a75e8d84c2bbb81 419 PRINTS PR00359 B-class P450 signature 371 382 7.2E-41 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS36730 6e1532bf47f004ac9a75e8d84c2bbb81 419 PRINTS PR00359 B-class P450 signature 340 355 7.2E-41 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS36730 6e1532bf47f004ac9a75e8d84c2bbb81 419 PRINTS PR00359 B-class P450 signature 104 115 7.2E-41 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS36730 6e1532bf47f004ac9a75e8d84c2bbb81 419 PRINTS PR00359 B-class P450 signature 167 182 7.2E-41 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS36730 6e1532bf47f004ac9a75e8d84c2bbb81 419 PRINTS PR00359 B-class P450 signature 213 235 7.2E-41 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS36730 6e1532bf47f004ac9a75e8d84c2bbb81 419 PRINTS PR00359 B-class P450 signature 362 371 7.2E-41 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS36730 6e1532bf47f004ac9a75e8d84c2bbb81 419 SUPERFAMILY SSF48264 55 409 1.31E-80 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS36730 6e1532bf47f004ac9a75e8d84c2bbb81 419 Pfam PF00067 Cytochrome P450 292 391 8.1E-17 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS36730 6e1532bf47f004ac9a75e8d84c2bbb81 419 Pfam PF00067 Cytochrome P450 224 281 8.3E-6 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS36730 6e1532bf47f004ac9a75e8d84c2bbb81 419 Gene3D G3DSA:1.10.630.10 5 419 5.0E-65 T 29-03-2018 SMALA_RS12795 95943d389a4ecdff8d8337da759c360f 283 SUPERFAMILY SSF47413 10 71 1.29E-9 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS12795 95943d389a4ecdff8d8337da759c360f 283 Gene3D G3DSA:1.10.3100.10 8 152 4.2E-12 T 29-03-2018 IPR027910 YdiL-like domain SMALA_RS12795 95943d389a4ecdff8d8337da759c360f 283 Pfam PF13560 Helix-turn-helix domain 13 71 8.7E-10 T 29-03-2018 SMALA_RS12795 95943d389a4ecdff8d8337da759c360f 283 SMART SM00530 17 72 6.7E-5 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS14735 9ca9b25da1661280849ea72c30b1ab1c 411 Gene3D G3DSA:3.40.47.10 35 216 2.3E-25 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS14735 9ca9b25da1661280849ea72c30b1ab1c 411 SUPERFAMILY SSF53901 7 235 1.77E-30 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS14735 9ca9b25da1661280849ea72c30b1ab1c 411 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 45 201 4.2E-12 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS14735 9ca9b25da1661280849ea72c30b1ab1c 411 Gene3D G3DSA:3.40.47.10 1 34 0.14 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS33155 e59be60a6521736f6540a2774e4df587 310 SUPERFAMILY SSF53328 1 206 4.06E-57 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SMALA_RS33155 e59be60a6521736f6540a2774e4df587 310 Pfam PF02911 Formyl transferase, C-terminal domain 204 300 2.5E-25 T 29-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SMALA_RS33155 e59be60a6521736f6540a2774e4df587 310 Pfam PF00551 Formyl transferase 2 174 4.1E-33 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SMALA_RS33155 e59be60a6521736f6540a2774e4df587 310 Gene3D G3DSA:3.40.50.170 1 206 7.0E-60 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SMALA_RS33155 e59be60a6521736f6540a2774e4df587 310 Gene3D G3DSA:3.10.25.10 207 310 6.3E-31 T 29-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SMALA_RS33155 e59be60a6521736f6540a2774e4df587 310 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 1 303 32.807 T 29-03-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 SMALA_RS33155 e59be60a6521736f6540a2774e4df587 310 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 1 301 6.9E-69 T 29-03-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 SMALA_RS33155 e59be60a6521736f6540a2774e4df587 310 SUPERFAMILY SSF50486 205 308 1.33E-28 T 29-03-2018 IPR011034 Formyl transferase, C-terminal-like GO:0003824 SMALA_RS33595 a845d024819c706b6dce22acf4f366f2 328 SUPERFAMILY SSF51430 1 315 6.02E-93 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS33595 a845d024819c706b6dce22acf4f366f2 328 Pfam PF00248 Aldo/keto reductase family 15 312 2.7E-69 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS33595 a845d024819c706b6dce22acf4f366f2 328 Gene3D G3DSA:3.20.20.100 1 317 2.2E-88 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS10640 68e6f0c3c3a37d64f0baf46f1479224c 366 Gene3D G3DSA:3.40.50.10210 75 335 9.2E-87 T 29-03-2018 SMALA_RS10640 68e6f0c3c3a37d64f0baf46f1479224c 366 Hamap MF_00230 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase [cobT]. 15 354 31.232 T 29-03-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 SMALA_RS10640 68e6f0c3c3a37d64f0baf46f1479224c 366 Pfam PF02277 Phosphoribosyltransferase 13 347 7.3E-104 T 29-03-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 SMALA_RS10640 68e6f0c3c3a37d64f0baf46f1479224c 366 TIGRFAM TIGR03160 cobT_DBIPRT: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 17 346 1.7E-101 T 29-03-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 SMALA_RS10640 68e6f0c3c3a37d64f0baf46f1479224c 366 SUPERFAMILY SSF52733 7 347 3.27E-91 T 29-03-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 SMALA_RS10640 68e6f0c3c3a37d64f0baf46f1479224c 366 Gene3D G3DSA:1.10.1610.10 7 74 6.6E-21 T 29-03-2018 IPR023195 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 SMALA_RS26305 10d8b91ea1f6954b9fdd70746b83b3b6 333 SUPERFAMILY SSF161098 90 318 1.06E-50 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS26305 10d8b91ea1f6954b9fdd70746b83b3b6 333 Gene3D G3DSA:1.10.3720.10 43 332 8.6E-45 T 29-03-2018 SMALA_RS26305 10d8b91ea1f6954b9fdd70746b83b3b6 333 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 123 321 3.6E-14 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS22955 ade33d066a9bf20ddc4222e5cbad921c 500 SUPERFAMILY SSF54631 75 211 4.8E-29 T 29-03-2018 SMALA_RS22955 ade33d066a9bf20ddc4222e5cbad921c 500 PIRSF PIRSF000130 7 500 1.2E-202 T 29-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 SMALA_RS22955 ade33d066a9bf20ddc4222e5cbad921c 500 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 301 313 - T 29-03-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 SMALA_RS22955 ade33d066a9bf20ddc4222e5cbad921c 500 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 16 468 3.4E-184 T 29-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 SMALA_RS22955 ade33d066a9bf20ddc4222e5cbad921c 500 SMART SM01240 15 486 0.0 T 29-03-2018 SMALA_RS22955 ade33d066a9bf20ddc4222e5cbad921c 500 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 16 499 84.399 T 29-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 SMALA_RS22955 ade33d066a9bf20ddc4222e5cbad921c 500 Pfam PF00571 CBS domain 101 149 6.0E-8 T 29-03-2018 IPR000644 CBS domain SMALA_RS22955 ade33d066a9bf20ddc4222e5cbad921c 500 Pfam PF00571 CBS domain 157 211 6.4E-6 T 29-03-2018 IPR000644 CBS domain SMALA_RS22955 ade33d066a9bf20ddc4222e5cbad921c 500 Gene3D G3DSA:3.20.20.70 7 494 7.8E-108 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS22955 ade33d066a9bf20ddc4222e5cbad921c 500 SUPERFAMILY SSF51412 11 98 5.49E-118 T 29-03-2018 SMALA_RS22955 ade33d066a9bf20ddc4222e5cbad921c 500 SUPERFAMILY SSF51412 224 490 5.49E-118 T 29-03-2018 SMALA_RS22955 ade33d066a9bf20ddc4222e5cbad921c 500 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 16 486 1.1E-157 T 29-03-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 SMALA_RS22955 ade33d066a9bf20ddc4222e5cbad921c 500 SMART SM00116 165 213 1.3E-7 T 29-03-2018 IPR000644 CBS domain SMALA_RS22955 ade33d066a9bf20ddc4222e5cbad921c 500 SMART SM00116 104 152 8.0E-8 T 29-03-2018 IPR000644 CBS domain SMALA_RS39530 a90e2d22bc4694c628b769bbc00431a1 566 Pfam PF00664 ABC transporter transmembrane region 39 295 1.9E-14 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMALA_RS39530 a90e2d22bc4694c628b769bbc00431a1 566 ProSitePatterns PS00211 ABC transporters family signature. 469 483 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS39530 a90e2d22bc4694c628b769bbc00431a1 566 Gene3D G3DSA:1.20.1560.10 5 325 6.4E-30 T 29-03-2018 SMALA_RS39530 a90e2d22bc4694c628b769bbc00431a1 566 Pfam PF00005 ABC transporter 349 496 1.9E-9 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS39530 a90e2d22bc4694c628b769bbc00431a1 566 Gene3D G3DSA:3.40.50.300 338 564 7.9E-37 T 29-03-2018 SMALA_RS39530 a90e2d22bc4694c628b769bbc00431a1 566 SUPERFAMILY SSF52540 337 562 2.49E-39 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS39530 a90e2d22bc4694c628b769bbc00431a1 566 SUPERFAMILY SSF90123 16 328 2.35E-38 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMALA_RS01970 2ca4e04b1a671dce7ccbbaaafd42e6ee 316 Gene3D G3DSA:1.20.58.370 11 67 2.0E-7 T 29-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain SMALA_RS01970 2ca4e04b1a671dce7ccbbaaafd42e6ee 316 Gene3D G3DSA:1.10.3720.10 86 315 4.6E-44 T 29-03-2018 SMALA_RS01970 2ca4e04b1a671dce7ccbbaaafd42e6ee 316 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 110 311 6.9E-19 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS01970 2ca4e04b1a671dce7ccbbaaafd42e6ee 316 SUPERFAMILY SSF161098 79 304 1.16E-62 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS02495 53e99f99a24513536f84f077f8f411e3 162 Pfam PF13463 Winged helix DNA-binding domain 43 102 1.5E-7 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS02495 53e99f99a24513536f84f077f8f411e3 162 Gene3D G3DSA:1.10.10.10 2 143 2.1E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS02495 53e99f99a24513536f84f077f8f411e3 162 PRINTS PR00598 Bacterial regulatory protein MarR family signature 119 139 4.5E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS02495 53e99f99a24513536f84f077f8f411e3 162 PRINTS PR00598 Bacterial regulatory protein MarR family signature 53 69 4.5E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS02495 53e99f99a24513536f84f077f8f411e3 162 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 85 4.5E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS02495 53e99f99a24513536f84f077f8f411e3 162 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 105 4.5E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS02495 53e99f99a24513536f84f077f8f411e3 162 SUPERFAMILY SSF46785 6 141 6.12E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS02495 53e99f99a24513536f84f077f8f411e3 162 SMART SM00347 30 129 5.2E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS32965 6c9b4c1c63e9b8744733f3f3fbf74328 420 SUPERFAMILY SSF55681 4 315 1.17E-81 T 29-03-2018 SMALA_RS32965 6c9b4c1c63e9b8744733f3f3fbf74328 420 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 5 407 4.1E-131 T 29-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 SMALA_RS32965 6c9b4c1c63e9b8744733f3f3fbf74328 420 Pfam PF03129 Anticodon binding domain 329 417 1.4E-12 T 29-03-2018 IPR004154 Anticodon-binding SMALA_RS32965 6c9b4c1c63e9b8744733f3f3fbf74328 420 Gene3D G3DSA:3.30.930.10 2 322 1.9E-62 T 29-03-2018 SMALA_RS32965 6c9b4c1c63e9b8744733f3f3fbf74328 420 PIRSF PIRSF001549 1 419 3.4E-102 T 29-03-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 SMALA_RS32965 6c9b4c1c63e9b8744733f3f3fbf74328 420 SUPERFAMILY SSF52954 326 419 1.18E-21 T 29-03-2018 IPR004154 Anticodon-binding SMALA_RS32965 6c9b4c1c63e9b8744733f3f3fbf74328 420 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 2 417 30.546 T 29-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 SMALA_RS32965 6c9b4c1c63e9b8744733f3f3fbf74328 420 Gene3D G3DSA:3.40.50.800 324 420 7.2E-17 T 29-03-2018 IPR004154 Anticodon-binding SMALA_RS32965 6c9b4c1c63e9b8744733f3f3fbf74328 420 Pfam PF13393 Histidyl-tRNA synthetase 9 309 1.2E-43 T 29-03-2018 SMALA_RS10515 c9fca15d87beabbf4469f870e23e4389 357 SUPERFAMILY SSF52418 88 356 9.94E-82 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 SMALA_RS10515 c9fca15d87beabbf4469f870e23e4389 357 SUPERFAMILY SSF47648 18 84 1.07E-20 T 29-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 SMALA_RS10515 c9fca15d87beabbf4469f870e23e4389 357 Gene3D G3DSA:1.20.970.10 12 85 2.2E-23 T 29-03-2018 SMALA_RS10515 c9fca15d87beabbf4469f870e23e4389 357 Pfam PF00591 Glycosyl transferase family, a/b domain 89 344 4.3E-78 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 SMALA_RS10515 c9fca15d87beabbf4469f870e23e4389 357 Gene3D G3DSA:3.40.1030.10 86 357 6.5E-100 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 SMALA_RS10515 c9fca15d87beabbf4469f870e23e4389 357 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 23 353 3.2E-109 T 29-03-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 SMALA_RS10515 c9fca15d87beabbf4469f870e23e4389 357 Pfam PF02885 Glycosyl transferase family, helical bundle domain 20 81 2.2E-19 T 29-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 SMALA_RS10515 c9fca15d87beabbf4469f870e23e4389 357 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 20 354 35.018 T 29-03-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 SMALA_RS06910 0507df69819a742bbffea5ec10265c4a 432 Pfam PF00196 Bacterial regulatory proteins, luxR family 348 401 2.1E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS06910 0507df69819a742bbffea5ec10265c4a 432 SMART SM00421 346 403 1.8E-15 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS06910 0507df69819a742bbffea5ec10265c4a 432 SUPERFAMILY SSF46894 339 404 4.76E-16 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS06910 0507df69819a742bbffea5ec10265c4a 432 Gene3D G3DSA:1.10.10.10 217 407 5.2E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS06910 0507df69819a742bbffea5ec10265c4a 432 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 349 363 1.3E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS06910 0507df69819a742bbffea5ec10265c4a 432 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 363 379 1.3E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS06910 0507df69819a742bbffea5ec10265c4a 432 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 379 391 1.3E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS21615 0f0b6e739212e6b820a50c1575018352 192 Gene3D G3DSA:1.10.10.60 1 35 6.0E-19 T 29-03-2018 SMALA_RS21615 0f0b6e739212e6b820a50c1575018352 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 2.6E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS21615 0f0b6e739212e6b820a50c1575018352 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 2.6E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS21615 0f0b6e739212e6b820a50c1575018352 192 ProSitePatterns PS01081 TetR-type HTH domain signature. 26 57 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site SMALA_RS21615 0f0b6e739212e6b820a50c1575018352 192 Gene3D G3DSA:1.10.260.40 36 181 6.3E-14 T 29-03-2018 SMALA_RS21615 0f0b6e739212e6b820a50c1575018352 192 SUPERFAMILY SSF46689 4 74 1.74E-20 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS21615 0f0b6e739212e6b820a50c1575018352 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 59 1.2E-18 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS07470 ddeb21e47414493ea5df20cadfc85399 445 SUPERFAMILY SSF53187 355 442 1.49E-54 T 29-03-2018 SMALA_RS07470 ddeb21e47414493ea5df20cadfc85399 445 SUPERFAMILY SSF53187 17 208 1.49E-54 T 29-03-2018 SMALA_RS07470 ddeb21e47414493ea5df20cadfc85399 445 PIRSF PIRSF036696 291 445 5.6E-5 T 29-03-2018 SMALA_RS07470 ddeb21e47414493ea5df20cadfc85399 445 PIRSF PIRSF036696 11 255 3.7E-34 T 29-03-2018 SMALA_RS07470 ddeb21e47414493ea5df20cadfc85399 445 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 87 96 - T 29-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 SMALA_RS07470 ddeb21e47414493ea5df20cadfc85399 445 Pfam PF01546 Peptidase family M20/M25/M40 88 443 9.6E-37 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 SMALA_RS07470 ddeb21e47414493ea5df20cadfc85399 445 SUPERFAMILY SSF55031 208 253 6.16E-10 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain SMALA_RS07470 ddeb21e47414493ea5df20cadfc85399 445 SUPERFAMILY SSF55031 294 333 6.16E-10 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain SMALA_RS07470 ddeb21e47414493ea5df20cadfc85399 445 Gene3D G3DSA:3.30.70.360 212 355 1.5E-23 T 29-03-2018 SMALA_RS07470 ddeb21e47414493ea5df20cadfc85399 445 Pfam PF07687 Peptidase dimerisation domain 205 333 6.1E-15 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain SMALA_RS07470 ddeb21e47414493ea5df20cadfc85399 445 Gene3D G3DSA:3.40.630.10 12 211 7.9E-44 T 29-03-2018 SMALA_RS04330 4eca126ad4c583060e90e9b5ece39945 418 Pfam PF13535 ATP-grasp domain 151 301 3.9E-17 T 29-03-2018 SMALA_RS04330 4eca126ad4c583060e90e9b5ece39945 418 Gene3D G3DSA:3.40.50.20 12 120 7.1E-12 T 29-03-2018 SMALA_RS04330 4eca126ad4c583060e90e9b5ece39945 418 SUPERFAMILY SSF56059 115 335 6.19E-38 T 29-03-2018 SMALA_RS04330 4eca126ad4c583060e90e9b5ece39945 418 SMART SM01209 116 296 7.0E-4 T 29-03-2018 SMALA_RS04330 4eca126ad4c583060e90e9b5ece39945 418 Gene3D G3DSA:3.30.470.20 121 409 6.2E-42 T 29-03-2018 SMALA_RS16775 f967d286be7de5273337b9399cbca4ba 406 Gene3D G3DSA:3.90.1150.10 301 406 1.1E-21 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS16775 f967d286be7de5273337b9399cbca4ba 406 Pfam PF00202 Aminotransferase class-III 19 403 4.1E-115 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMALA_RS16775 f967d286be7de5273337b9399cbca4ba 406 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 229 266 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMALA_RS16775 f967d286be7de5273337b9399cbca4ba 406 Gene3D G3DSA:3.40.640.10 183 300 7.2E-46 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS16775 f967d286be7de5273337b9399cbca4ba 406 SUPERFAMILY SSF53383 8 405 4.37E-119 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS16775 f967d286be7de5273337b9399cbca4ba 406 TIGRFAM TIGR01885 Orn_aminotrans: ornithine--oxo-acid transaminase 8 404 1.1E-145 T 29-03-2018 IPR010164 Ornithine aminotransferase GO:0004587 KEGG: 00330+2.6.1.13|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|MetaCyc: PWY-6922|Reactome: R-HSA-70614 SMALA_RS16775 f967d286be7de5273337b9399cbca4ba 406 PIRSF PIRSF000521 177 406 1.5E-30 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMALA_RS16775 f967d286be7de5273337b9399cbca4ba 406 PIRSF PIRSF000521 3 172 9.1E-8 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMALA_RS16775 f967d286be7de5273337b9399cbca4ba 406 Gene3D G3DSA:3.90.1150.10 5 182 1.7E-43 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS06045 95185514beeb5900842f4d391f1108b8 435 Pfam PF01547 Bacterial extracellular solute-binding protein 63 339 6.1E-27 T 29-03-2018 IPR006059 Solute-binding family 1 GO:0006810 SMALA_RS06045 95185514beeb5900842f4d391f1108b8 435 Gene3D G3DSA:3.40.190.10 15 173 3.5E-15 T 29-03-2018 SMALA_RS06045 95185514beeb5900842f4d391f1108b8 435 Gene3D G3DSA:3.40.190.10 174 382 7.2E-32 T 29-03-2018 SMALA_RS06045 95185514beeb5900842f4d391f1108b8 435 SUPERFAMILY SSF53850 31 427 1.77E-52 T 29-03-2018 SMALA_RS25245 d02ffeb7d6475db0662a6136837ac53b 563 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 260 273 - T 29-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 SMALA_RS25245 d02ffeb7d6475db0662a6136837ac53b 563 Gene3D G3DSA:3.20.20.70 27 403 1.2E-108 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS25245 d02ffeb7d6475db0662a6136837ac53b 563 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 57 73 - T 29-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 SMALA_RS25245 d02ffeb7d6475db0662a6136837ac53b 563 Hamap MF_00572 2-isopropylmalate synthase [leuA]. 21 563 48.182 T 29-03-2018 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 SMALA_RS25245 d02ffeb7d6475db0662a6136837ac53b 563 SUPERFAMILY SSF89000 415 464 7.06E-11 T 29-03-2018 SMALA_RS25245 d02ffeb7d6475db0662a6136837ac53b 563 SUPERFAMILY SSF51569 39 347 1.14E-94 T 29-03-2018 SMALA_RS25245 d02ffeb7d6475db0662a6136837ac53b 563 SUPERFAMILY SSF110921 480 560 4.32E-5 T 29-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 SMALA_RS25245 d02ffeb7d6475db0662a6136837ac53b 563 Pfam PF00682 HMGL-like 51 330 2.0E-72 T 29-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 SMALA_RS11670 3a59523321115a52cb8d32b0d77c4ebf 660 Pfam PF13454 FAD-NAD(P)-binding 9 175 2.1E-48 T 29-03-2018 SMALA_RS11670 3a59523321115a52cb8d32b0d77c4ebf 660 Gene3D G3DSA:3.50.50.60 6 647 5.0E-8 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS11670 3a59523321115a52cb8d32b0d77c4ebf 660 SUPERFAMILY SSF51905 8 58 7.61E-5 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS11670 3a59523321115a52cb8d32b0d77c4ebf 660 SUPERFAMILY SSF51905 114 182 7.61E-5 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS11670 3a59523321115a52cb8d32b0d77c4ebf 660 SUPERFAMILY SSF51905 572 612 7.61E-5 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS29740 862a91fd82a6af28573e9872f5647a53 1093 Gene3D G3DSA:2.70.98.10 37 369 1.9E-98 T 29-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 SMALA_RS29740 862a91fd82a6af28573e9872f5647a53 1093 Gene3D G3DSA:2.60.40.10 848 910 2.2E-4 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS29740 862a91fd82a6af28573e9872f5647a53 1093 Gene3D G3DSA:1.20.1050.60 394 488 2.5E-16 T 29-03-2018 SMALA_RS29740 862a91fd82a6af28573e9872f5647a53 1093 Gene3D G3DSA:2.60.40.10 787 847 9.7E-4 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS29740 862a91fd82a6af28573e9872f5647a53 1093 TIGRFAM TIGR01180 aman2_put: putative alpha-1,2-mannosidase 34 788 1.8E-151 T 29-03-2018 IPR005887 Alpha-1,2-mannosidase, putative SMALA_RS29740 862a91fd82a6af28573e9872f5647a53 1093 Pfam PF07971 Glycosyl hydrolase family 92 285 785 1.8E-154 T 29-03-2018 IPR012939 Glycosyl hydrolase family 92 SMALA_RS29740 862a91fd82a6af28573e9872f5647a53 1093 Gene3D G3DSA:1.20.1610.10 500 654 1.5E-47 T 29-03-2018 SMALA_RS29740 862a91fd82a6af28573e9872f5647a53 1093 Gene3D G3DSA:3.30.2080.10 655 786 8.9E-52 T 29-03-2018 SMALA_RS29740 862a91fd82a6af28573e9872f5647a53 1093 SUPERFAMILY SSF48208 308 762 6.73E-23 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 SMALA_RS01825 72f63b9ae9b141ddee668a1587984680 477 Gene3D G3DSA:1.10.630.10 54 416 1.1E-26 T 29-03-2018 SMALA_RS01825 72f63b9ae9b141ddee668a1587984680 477 SUPERFAMILY SSF48264 92 393 7.2E-31 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS01825 72f63b9ae9b141ddee668a1587984680 477 Pfam PF00067 Cytochrome P450 236 393 2.3E-13 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS01525 a40972c236f606542a31ffab2c1817ea 257 TIGRFAM TIGR03943 TIGR03943: TIGR03943 family protein 24 247 5.6E-47 T 29-03-2018 IPR015402 Protein of unknown function DUF1980 SMALA_RS19895 40b679f5cbb44737b5f8f53e1268ce3f 287 Gene3D G3DSA:1.10.287.110 93 281 6.7E-5 T 29-03-2018 IPR001623 DnaJ domain SMALA_RS20785 b1d6a23ce15ee57ecd1b4ec4ee80189c 241 Pfam PF00196 Bacterial regulatory proteins, luxR family 176 231 8.1E-18 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS20785 b1d6a23ce15ee57ecd1b4ec4ee80189c 241 SUPERFAMILY SSF46894 166 237 2.01E-22 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS20785 b1d6a23ce15ee57ecd1b4ec4ee80189c 241 Gene3D G3DSA:3.40.50.2300 18 150 1.4E-37 T 29-03-2018 SMALA_RS20785 b1d6a23ce15ee57ecd1b4ec4ee80189c 241 SMART SM00448 19 132 2.7E-31 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS20785 b1d6a23ce15ee57ecd1b4ec4ee80189c 241 Gene3D G3DSA:1.10.10.10 151 236 1.3E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS20785 b1d6a23ce15ee57ecd1b4ec4ee80189c 241 SMART SM00421 174 231 1.8E-25 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS20785 b1d6a23ce15ee57ecd1b4ec4ee80189c 241 SUPERFAMILY SSF52172 18 150 7.26E-34 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS20785 b1d6a23ce15ee57ecd1b4ec4ee80189c 241 ProSitePatterns PS00622 LuxR-type HTH domain signature. 191 218 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS20785 b1d6a23ce15ee57ecd1b4ec4ee80189c 241 Pfam PF00072 Response regulator receiver domain 21 132 2.2E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS20785 b1d6a23ce15ee57ecd1b4ec4ee80189c 241 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 191 207 4.4E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS20785 b1d6a23ce15ee57ecd1b4ec4ee80189c 241 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 177 191 4.4E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS20785 b1d6a23ce15ee57ecd1b4ec4ee80189c 241 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 207 219 4.4E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS05200 639d728ef10288ba3fdd06ebc677b660 362 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 23 127 1.4E-20 T 29-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain SMALA_RS05200 639d728ef10288ba3fdd06ebc677b660 362 SMART SM00922 147 244 7.8E-26 T 29-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal SMALA_RS05200 639d728ef10288ba3fdd06ebc677b660 362 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 194 225 - T 29-03-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 SMALA_RS05200 639d728ef10288ba3fdd06ebc677b660 362 Gene3D G3DSA:3.30.390.10 1 132 3.7E-31 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMALA_RS05200 639d728ef10288ba3fdd06ebc677b660 362 Gene3D G3DSA:3.20.20.120 133 352 1.5E-62 T 29-03-2018 IPR029065 Enolase C-terminal domain-like SMALA_RS05200 639d728ef10288ba3fdd06ebc677b660 362 SUPERFAMILY SSF54826 11 131 8.99E-29 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMALA_RS05200 639d728ef10288ba3fdd06ebc677b660 362 SUPERFAMILY SSF51604 116 360 1.57E-73 T 29-03-2018 IPR029065 Enolase C-terminal domain-like SMALA_RS05200 639d728ef10288ba3fdd06ebc677b660 362 Pfam PF13378 Enolase C-terminal domain-like 150 354 4.7E-62 T 29-03-2018 IPR029065 Enolase C-terminal domain-like SMALA_RS36060 f0b5007e41c3613f4a7e38dd243aa035 611 SUPERFAMILY SSF52518 4 266 1.01E-76 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold SMALA_RS36060 f0b5007e41c3613f4a7e38dd243aa035 611 SUPERFAMILY SSF52518 294 469 8.83E-49 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold SMALA_RS36060 f0b5007e41c3613f4a7e38dd243aa035 611 Gene3D G3DSA:3.40.50.970 295 477 2.6E-40 T 29-03-2018 SMALA_RS36060 f0b5007e41c3613f4a7e38dd243aa035 611 SUPERFAMILY SSF52922 473 609 1.57E-29 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMALA_RS36060 f0b5007e41c3613f4a7e38dd243aa035 611 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 11 260 1.1E-44 T 29-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SMALA_RS36060 f0b5007e41c3613f4a7e38dd243aa035 611 Gene3D G3DSA:3.40.50.970 1 294 7.6E-70 T 29-03-2018 SMALA_RS36060 f0b5007e41c3613f4a7e38dd243aa035 611 Pfam PF02779 Transketolase, pyrimidine binding domain 304 463 2.2E-34 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain SMALA_RS36060 f0b5007e41c3613f4a7e38dd243aa035 611 ProSitePatterns PS00802 Transketolase signature 2. 410 426 - T 29-03-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SMALA_RS36060 f0b5007e41c3613f4a7e38dd243aa035 611 Pfam PF02780 Transketolase, C-terminal domain 481 600 1.3E-28 T 29-03-2018 IPR033248 Transketolase, C-terminal domain SMALA_RS36060 f0b5007e41c3613f4a7e38dd243aa035 611 SMART SM00861 304 467 1.3E-41 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain SMALA_RS36060 f0b5007e41c3613f4a7e38dd243aa035 611 Gene3D G3DSA:3.40.50.920 478 611 1.4E-34 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMALA_RS27520 191e815b3e51fff22e8b4e81fdeb82ca 126 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 4 125 38.316 T 29-03-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 SMALA_RS27520 191e815b3e51fff22e8b4e81fdeb82ca 126 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 49 78 - T 29-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 SMALA_RS27520 191e815b3e51fff22e8b4e81fdeb82ca 126 SUPERFAMILY SSF51230 4 125 8.25E-39 T 29-03-2018 IPR011053 Single hybrid motif SMALA_RS27520 191e815b3e51fff22e8b4e81fdeb82ca 126 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 3 124 3.7E-44 T 29-03-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 SMALA_RS27520 191e815b3e51fff22e8b4e81fdeb82ca 126 Pfam PF01597 Glycine cleavage H-protein 7 125 3.0E-41 T 29-03-2018 IPR033753 Glycine cleavage system H-protein/Simiate SMALA_RS27520 191e815b3e51fff22e8b4e81fdeb82ca 126 Gene3D G3DSA:2.40.50.100 5 126 1.9E-42 T 29-03-2018 SMALA_RS04250 0312b9d5aa9385bb3984bb7c14c6a825 225 Pfam PF13578 Methyltransferase domain 81 183 2.2E-18 T 29-03-2018 SMALA_RS04250 0312b9d5aa9385bb3984bb7c14c6a825 225 Gene3D G3DSA:3.40.50.150 45 209 1.1E-27 T 29-03-2018 SMALA_RS04250 0312b9d5aa9385bb3984bb7c14c6a825 225 SUPERFAMILY SSF53335 43 200 3.34E-28 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS03065 839b6c7967d401af6eb09ea8c86491f8 466 ProSitePatterns PS00163 Fumarate lyases signature. 320 329 - T 29-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 SMALA_RS03065 839b6c7967d401af6eb09ea8c86491f8 466 Gene3D G3DSA:1.20.200.10 142 418 1.6E-80 T 29-03-2018 SMALA_RS03065 839b6c7967d401af6eb09ea8c86491f8 466 Pfam PF10415 Fumarase C C-terminus 411 462 1.6E-19 T 29-03-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 SMALA_RS03065 839b6c7967d401af6eb09ea8c86491f8 466 Gene3D G3DSA:1.10.275.10 4 141 7.7E-53 T 29-03-2018 IPR024083 Fumarase/histidase, N-terminal SMALA_RS03065 839b6c7967d401af6eb09ea8c86491f8 466 TIGRFAM TIGR00839 aspA: aspartate ammonia-lyase 7 462 3.1E-210 T 29-03-2018 IPR004708 Aspartate ammonia-lyase GO:0006531|GO:0008797 KEGG: 00250+4.3.1.1 SMALA_RS03065 839b6c7967d401af6eb09ea8c86491f8 466 Gene3D G3DSA:1.10.40.30 419 461 7.3E-19 T 29-03-2018 SMALA_RS03065 839b6c7967d401af6eb09ea8c86491f8 466 Pfam PF00206 Lyase 15 345 2.1E-103 T 29-03-2018 IPR022761 Fumarate lyase, N-terminal SMALA_RS03065 839b6c7967d401af6eb09ea8c86491f8 466 PRINTS PR00149 Fumarate lyase superfamily signature 183 201 4.2E-28 T 29-03-2018 IPR000362 Fumarate lyase family SMALA_RS03065 839b6c7967d401af6eb09ea8c86491f8 466 PRINTS PR00149 Fumarate lyase superfamily signature 320 336 4.2E-28 T 29-03-2018 IPR000362 Fumarate lyase family SMALA_RS03065 839b6c7967d401af6eb09ea8c86491f8 466 PRINTS PR00149 Fumarate lyase superfamily signature 138 156 4.2E-28 T 29-03-2018 IPR000362 Fumarate lyase family SMALA_RS03065 839b6c7967d401af6eb09ea8c86491f8 466 PRINTS PR00149 Fumarate lyase superfamily signature 274 301 4.2E-28 T 29-03-2018 IPR000362 Fumarate lyase family SMALA_RS03065 839b6c7967d401af6eb09ea8c86491f8 466 SUPERFAMILY SSF48557 6 461 2.36E-151 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 SMALA_RS03815 dbbed891109e604deaa527d603b8c9a8 268 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 143 151 8.7E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS03815 dbbed891109e604deaa527d603b8c9a8 268 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 163 182 8.7E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS03815 dbbed891109e604deaa527d603b8c9a8 268 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 90 101 8.7E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS03815 dbbed891109e604deaa527d603b8c9a8 268 TIGRFAM TIGR01963 PHB_DH: 3-hydroxybutyrate dehydrogenase 22 268 2.1E-103 T 29-03-2018 IPR011294 3-hydroxybutyrate dehydrogenase GO:0003858|GO:0055114 SMALA_RS03815 dbbed891109e604deaa527d603b8c9a8 268 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 150 178 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMALA_RS03815 dbbed891109e604deaa527d603b8c9a8 268 Gene3D G3DSA:3.40.50.720 11 266 1.1E-69 T 29-03-2018 SMALA_RS03815 dbbed891109e604deaa527d603b8c9a8 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 23 40 1.9E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS03815 dbbed891109e604deaa527d603b8c9a8 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 229 249 1.9E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS03815 dbbed891109e604deaa527d603b8c9a8 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 137 153 1.9E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS03815 dbbed891109e604deaa527d603b8c9a8 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 90 101 1.9E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS03815 dbbed891109e604deaa527d603b8c9a8 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 182 1.9E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS03815 dbbed891109e604deaa527d603b8c9a8 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 184 201 1.9E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS03815 dbbed891109e604deaa527d603b8c9a8 268 SUPERFAMILY SSF51735 17 267 1.58E-72 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS03815 dbbed891109e604deaa527d603b8c9a8 268 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 28 266 4.5E-49 T 29-03-2018 SMALA_RS35985 715a15d2d4ec5a6e4d3e469796539e92 261 Gene3D G3DSA:3.40.50.1820 3 252 6.6E-33 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS35985 715a15d2d4ec5a6e4d3e469796539e92 261 SUPERFAMILY SSF53474 8 249 2.25E-48 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS35985 715a15d2d4ec5a6e4d3e469796539e92 261 Pfam PF00975 Thioesterase domain 25 247 1.2E-48 T 29-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 SMALA_RS11355 14c658d9368f97992f2cbd1910178c32 286 SUPERFAMILY SSF102705 4 269 8.76E-81 T 29-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 SMALA_RS11355 14c658d9368f97992f2cbd1910178c32 286 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 5 236 1.0E-47 T 29-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 SMALA_RS11355 14c658d9368f97992f2cbd1910178c32 286 Gene3D G3DSA:3.40.1390.30 112 233 3.8E-37 T 29-03-2018 SMALA_RS11355 14c658d9368f97992f2cbd1910178c32 286 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 6 247 2.1E-71 T 29-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 SMALA_RS11355 14c658d9368f97992f2cbd1910178c32 286 Gene3D G3DSA:3.40.1390.30 2 111 3.6E-36 T 29-03-2018 SMALA_RS18990 c8224128b3c2c4ef8748948b67f998fc 136 Pfam PF03965 Penicillinase repressor 21 128 3.3E-22 T 29-03-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 SMALA_RS18990 c8224128b3c2c4ef8748948b67f998fc 136 Gene3D G3DSA:1.10.10.10 21 83 1.2E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS18990 c8224128b3c2c4ef8748948b67f998fc 136 SUPERFAMILY SSF46785 21 129 5.19E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS00950 f203c54ef62a83669c9c065047f86e90 332 SUPERFAMILY SSF56176 1 220 3.49E-55 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SMALA_RS00950 f203c54ef62a83669c9c065047f86e90 332 SUPERFAMILY SSF55447 228 329 1.57E-22 T 29-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal SMALA_RS00950 f203c54ef62a83669c9c065047f86e90 332 Gene3D G3DSA:3.30.43.10 1 51 5.6E-18 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 SMALA_RS00950 f203c54ef62a83669c9c065047f86e90 332 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 3 220 4.0E-44 T 29-03-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 SMALA_RS00950 f203c54ef62a83669c9c065047f86e90 332 Gene3D G3DSA:3.30.465.10 56 221 8.0E-30 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SMALA_RS00950 f203c54ef62a83669c9c065047f86e90 332 SMART SM01092 227 326 2.0E-22 T 29-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal SMALA_RS00950 f203c54ef62a83669c9c065047f86e90 332 Gene3D G3DSA:3.30.390.50 224 332 4.9E-22 T 29-03-2018 SMALA_RS00950 f203c54ef62a83669c9c065047f86e90 332 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 228 323 1.6E-14 T 29-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal SMALA_RS23060 86d97962e7e1060b362bce26883b7b65 345 SUPERFAMILY SSF46689 283 333 2.58E-10 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS23060 86d97962e7e1060b362bce26883b7b65 345 Gene3D G3DSA:3.40.50.880 13 246 6.8E-62 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS23060 86d97962e7e1060b362bce26883b7b65 345 Pfam PF01965 DJ-1/PfpI family 18 191 1.0E-12 T 29-03-2018 IPR002818 DJ-1/PfpI SMALA_RS23060 86d97962e7e1060b362bce26883b7b65 345 Gene3D G3DSA:1.10.10.60 285 338 1.3E-15 T 29-03-2018 SMALA_RS23060 86d97962e7e1060b362bce26883b7b65 345 Pfam PF12833 Helix-turn-helix domain 252 330 2.6E-22 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS23060 86d97962e7e1060b362bce26883b7b65 345 Gene3D G3DSA:1.10.10.60 247 284 1.3E-12 T 29-03-2018 SMALA_RS23060 86d97962e7e1060b362bce26883b7b65 345 SUPERFAMILY SSF46689 234 280 2.39E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS23060 86d97962e7e1060b362bce26883b7b65 345 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 283 325 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 SMALA_RS23060 86d97962e7e1060b362bce26883b7b65 345 SUPERFAMILY SSF52317 18 212 2.55E-45 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS23060 86d97962e7e1060b362bce26883b7b65 345 SMART SM00342 246 329 5.2E-30 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS06515 d69100366fe20bdbf7fb513d2825998c 206 Gene3D G3DSA:1.10.10.60 9 65 2.9E-14 T 29-03-2018 SMALA_RS06515 d69100366fe20bdbf7fb513d2825998c 206 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 65 2.6E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS06515 d69100366fe20bdbf7fb513d2825998c 206 SUPERFAMILY SSF48498 87 203 1.21E-20 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS06515 d69100366fe20bdbf7fb513d2825998c 206 SUPERFAMILY SSF46689 5 80 1.08E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS06515 d69100366fe20bdbf7fb513d2825998c 206 Gene3D G3DSA:1.10.357.10 66 204 1.5E-17 T 29-03-2018 SMALA_RS03590 ceb2ab616e87ed8d895c9306e706d011 88 Pfam PF02467 Transcription factor WhiB 3 72 2.1E-24 T 29-03-2018 IPR034768 WhiB-like iron-sulfur binding domain SMALA_RS03590 ceb2ab616e87ed8d895c9306e706d011 88 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 77 18.154 T 29-03-2018 IPR003482 Transcription factor WhiB SMALA_RS16785 9594f043681aa5f57ac6feab0a991042 161 SUPERFAMILY SSF69118 13 154 1.57E-40 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 SMALA_RS16785 9594f043681aa5f57ac6feab0a991042 161 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 38 85 4.0E-17 T 29-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SMALA_RS16785 9594f043681aa5f57ac6feab0a991042 161 Pfam PF02627 Carboxymuconolactone decarboxylase family 21 102 1.9E-18 T 29-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SMALA_RS16785 9594f043681aa5f57ac6feab0a991042 161 Gene3D G3DSA:1.20.1290.10 10 159 2.7E-35 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 SMALA_RS16520 1e728331e0ea31b308aad0deb8e5ee19 344 SUPERFAMILY SSF53822 47 276 2.3E-11 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SMALA_RS16520 1e728331e0ea31b308aad0deb8e5ee19 344 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 42 340 1.2E-51 T 29-03-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 SMALA_RS16520 1e728331e0ea31b308aad0deb8e5ee19 344 Gene3D G3DSA:3.40.50.2300 33 151 7.4E-35 T 29-03-2018 SMALA_RS16520 1e728331e0ea31b308aad0deb8e5ee19 344 Gene3D G3DSA:3.40.50.2300 152 344 1.1E-43 T 29-03-2018 SMALA_RS18420 d90f14c275b4a8cd953fb09fc7e2eced 490 ProSitePatterns PS00217 Sugar transport proteins signature 2. 140 165 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMALA_RS18420 d90f14c275b4a8cd953fb09fc7e2eced 490 ProSitePatterns PS00216 Sugar transport proteins signature 1. 98 114 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMALA_RS18420 d90f14c275b4a8cd953fb09fc7e2eced 490 SUPERFAMILY SSF103473 19 467 2.22E-78 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS18420 d90f14c275b4a8cd953fb09fc7e2eced 490 Pfam PF07690 Major Facilitator Superfamily 49 394 1.2E-45 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS18420 d90f14c275b4a8cd953fb09fc7e2eced 490 Gene3D G3DSA:1.20.1250.20 32 233 1.1E-42 T 29-03-2018 SMALA_RS18420 d90f14c275b4a8cd953fb09fc7e2eced 490 Gene3D G3DSA:1.20.1250.20 255 479 1.5E-21 T 29-03-2018 SMALA_RS26935 9666bec9e81da6ad412186b7c39899f3 229 Gene3D G3DSA:3.40.50.2300 14 145 2.0E-34 T 29-03-2018 SMALA_RS26935 9666bec9e81da6ad412186b7c39899f3 229 Pfam PF00196 Bacterial regulatory proteins, luxR family 168 223 7.1E-20 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS26935 9666bec9e81da6ad412186b7c39899f3 229 ProSitePatterns PS00622 LuxR-type HTH domain signature. 183 210 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS26935 9666bec9e81da6ad412186b7c39899f3 229 SUPERFAMILY SSF52172 14 144 2.13E-30 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS26935 9666bec9e81da6ad412186b7c39899f3 229 Gene3D G3DSA:1.10.10.10 146 227 4.4E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS26935 9666bec9e81da6ad412186b7c39899f3 229 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 199 211 3.5E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS26935 9666bec9e81da6ad412186b7c39899f3 229 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 183 3.5E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS26935 9666bec9e81da6ad412186b7c39899f3 229 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 183 199 3.5E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS26935 9666bec9e81da6ad412186b7c39899f3 229 SMART SM00448 15 127 2.3E-28 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS26935 9666bec9e81da6ad412186b7c39899f3 229 SMART SM00421 166 223 3.8E-25 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS26935 9666bec9e81da6ad412186b7c39899f3 229 SUPERFAMILY SSF46894 159 228 2.04E-21 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS26935 9666bec9e81da6ad412186b7c39899f3 229 Pfam PF00072 Response regulator receiver domain 17 128 2.8E-22 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS09520 49d89dc9ff38def563747af56525b8bc 316 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 27 314 19.449 T 29-03-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 SMALA_RS09520 49d89dc9ff38def563747af56525b8bc 316 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 82 104 - T 29-03-2018 IPR030470 UbiA prenyltransferase conserved site SMALA_RS09520 49d89dc9ff38def563747af56525b8bc 316 Pfam PF01040 UbiA prenyltransferase family 43 299 4.2E-65 T 29-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 SMALA_RS09520 49d89dc9ff38def563747af56525b8bc 316 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 29 312 1.4E-96 T 29-03-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 SMALA_RS33005 b45cea530a8db5d531718444f1ecfbda 203 Pfam PF01479 S4 domain 91 138 1.0E-16 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SMALA_RS33005 b45cea530a8db5d531718444f1ecfbda 203 SUPERFAMILY SSF55174 5 203 2.22E-54 T 29-03-2018 SMALA_RS33005 b45cea530a8db5d531718444f1ecfbda 203 Gene3D G3DSA:1.10.1050.10 141 203 1.1E-10 T 29-03-2018 SMALA_RS33005 b45cea530a8db5d531718444f1ecfbda 203 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 5 203 5.4E-60 T 29-03-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 SMALA_RS33005 b45cea530a8db5d531718444f1ecfbda 203 Gene3D G3DSA:3.10.290.10 96 140 4.0E-16 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SMALA_RS33005 b45cea530a8db5d531718444f1ecfbda 203 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 5 90 7.0E-21 T 29-03-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 SMALA_RS33005 b45cea530a8db5d531718444f1ecfbda 203 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 203 28.997 T 29-03-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 SMALA_RS33005 b45cea530a8db5d531718444f1ecfbda 203 SMART SM00363 91 155 6.4E-14 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SMALA_RS33005 b45cea530a8db5d531718444f1ecfbda 203 ProSitePatterns PS00632 Ribosomal protein S4 signature. 89 113 - T 29-03-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMALA_RS33005 b45cea530a8db5d531718444f1ecfbda 203 SMART SM01390 2 90 3.3E-32 T 29-03-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 SMALA_RS33005 b45cea530a8db5d531718444f1ecfbda 203 Gene3D G3DSA:1.10.1050.10 1 95 1.3E-28 T 29-03-2018 SMALA_RS18095 53c39d776069520abb4b3f8af3f0f73f 122 Gene3D G3DSA:3.30.1130.10 4 121 8.1E-38 T 29-03-2018 SMALA_RS18095 53c39d776069520abb4b3f8af3f0f73f 122 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 5 119 2.5E-35 T 29-03-2018 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 SMALA_RS18095 53c39d776069520abb4b3f8af3f0f73f 122 Pfam PF02152 Dihydroneopterin aldolase 8 118 1.3E-35 T 29-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 SMALA_RS18095 53c39d776069520abb4b3f8af3f0f73f 122 TIGRFAM TIGR00526 folB_dom: FolB domain 5 121 2.3E-31 T 29-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 SMALA_RS18095 53c39d776069520abb4b3f8af3f0f73f 122 SUPERFAMILY SSF55620 5 121 1.83E-36 T 29-03-2018 SMALA_RS18095 53c39d776069520abb4b3f8af3f0f73f 122 SMART SM00905 7 119 3.3E-48 T 29-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 SMALA_RS16340 69329ca94ec7af84ad34099cec5dfbf9 532 Gene3D G3DSA:3.90.226.10 273 517 7.4E-75 T 29-03-2018 SMALA_RS16340 69329ca94ec7af84ad34099cec5dfbf9 532 Pfam PF01039 Carboxyl transferase domain 42 530 1.4E-195 T 29-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 SMALA_RS16340 69329ca94ec7af84ad34099cec5dfbf9 532 SUPERFAMILY SSF52096 20 270 8.35E-81 T 29-03-2018 IPR029045 ClpP/crotonase-like domain SMALA_RS16340 69329ca94ec7af84ad34099cec5dfbf9 532 SUPERFAMILY SSF52096 257 532 6.1E-90 T 29-03-2018 IPR029045 ClpP/crotonase-like domain SMALA_RS16340 69329ca94ec7af84ad34099cec5dfbf9 532 Gene3D G3DSA:3.90.226.10 8 272 4.6E-83 T 29-03-2018 SMALA_RS16340 69329ca94ec7af84ad34099cec5dfbf9 532 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 143 161 4.6E-6 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 SMALA_RS16340 69329ca94ec7af84ad34099cec5dfbf9 532 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 109 123 4.6E-6 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 SMALA_RS32570 42b90e7739184954952dff02f4830bf8 274 PIRSF PIRSF002854 2 274 1.1E-108 T 29-03-2018 IPR004872 Lipoprotein NlpA family SMALA_RS32570 42b90e7739184954952dff02f4830bf8 274 Gene3D G3DSA:3.40.190.10 34 131 7.3E-20 T 29-03-2018 SMALA_RS32570 42b90e7739184954952dff02f4830bf8 274 SUPERFAMILY SSF53850 37 274 5.26E-82 T 29-03-2018 SMALA_RS32570 42b90e7739184954952dff02f4830bf8 274 Pfam PF03180 NLPA lipoprotein 38 273 9.1E-93 T 29-03-2018 IPR004872 Lipoprotein NlpA family SMALA_RS32570 42b90e7739184954952dff02f4830bf8 274 Gene3D G3DSA:3.40.190.10 132 274 3.3E-56 T 29-03-2018 SMALA_RS18005 a3d7609f1d0b95a3ba81e01e2a73533a 323 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 38 316 1.0E-78 T 29-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 SMALA_RS18005 a3d7609f1d0b95a3ba81e01e2a73533a 323 Pfam PF02569 Pantoate-beta-alanine ligase 37 315 2.3E-89 T 29-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 SMALA_RS18005 a3d7609f1d0b95a3ba81e01e2a73533a 323 SUPERFAMILY SSF52374 19 319 4.13E-89 T 29-03-2018 SMALA_RS18005 a3d7609f1d0b95a3ba81e01e2a73533a 323 Hamap MF_00158 Pantothenate synthetase [panC]. 17 317 38.321 T 29-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 SMALA_RS18005 a3d7609f1d0b95a3ba81e01e2a73533a 323 Gene3D G3DSA:3.40.50.620 8 192 1.4E-68 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS18005 a3d7609f1d0b95a3ba81e01e2a73533a 323 Gene3D G3DSA:3.30.1300.10 193 323 6.5E-39 T 29-03-2018 SMALA_RS03745 0e4cdbe428a4ea5dd324130b1aef069b 797 Pfam PF00005 ABC transporter 508 715 1.9E-11 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS03745 0e4cdbe428a4ea5dd324130b1aef069b 797 SUPERFAMILY SSF52540 501 769 8.74E-39 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS03745 0e4cdbe428a4ea5dd324130b1aef069b 797 Gene3D G3DSA:3.40.50.300 483 794 2.4E-53 T 29-03-2018 SMALA_RS03745 0e4cdbe428a4ea5dd324130b1aef069b 797 SMART SM00382 517 761 0.27 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS03745 0e4cdbe428a4ea5dd324130b1aef069b 797 SMART SM00382 42 454 2.1 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS03745 0e4cdbe428a4ea5dd324130b1aef069b 797 Gene3D G3DSA:3.40.50.300 22 123 1.9E-4 T 29-03-2018 SMALA_RS03745 0e4cdbe428a4ea5dd324130b1aef069b 797 SUPERFAMILY SSF52540 23 71 3.69E-32 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS03745 0e4cdbe428a4ea5dd324130b1aef069b 797 SUPERFAMILY SSF52540 329 459 3.69E-32 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS03745 0e4cdbe428a4ea5dd324130b1aef069b 797 Gene3D G3DSA:1.20.1580.10 124 377 3.9E-55 T 29-03-2018 SMALA_RS17510 e17ebac5a6b598132cb650c80be6d252 92 Gene3D G3DSA:3.10.20.30 1 91 5.4E-22 T 29-03-2018 IPR012675 Beta-grasp domain SMALA_RS17510 e17ebac5a6b598132cb650c80be6d252 92 Pfam PF02597 ThiS family 5 91 8.4E-18 T 29-03-2018 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 SMALA_RS17510 e17ebac5a6b598132cb650c80be6d252 92 SUPERFAMILY SSF54285 1 91 3.6E-22 T 29-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp SMALA_RS41360 d4a692abe10b2a122720a205cf8c59c5 209 SUPERFAMILY SSF69118 15 199 1.44E-24 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 SMALA_RS41360 d4a692abe10b2a122720a205cf8c59c5 209 Gene3D G3DSA:1.20.1290.10 59 207 1.8E-21 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 SMALA_RS38655 44d09b4efad773c923a7d1ee1d23efcf 268 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 82 255 1.2E-17 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS38655 44d09b4efad773c923a7d1ee1d23efcf 268 Gene3D G3DSA:1.10.3720.10 2 254 7.4E-44 T 29-03-2018 SMALA_RS38655 44d09b4efad773c923a7d1ee1d23efcf 268 SUPERFAMILY SSF161098 3 255 4.19E-54 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS01925 90bd13fd99e653fc6673edf277cba649 396 Gene3D G3DSA:3.30.420.40 205 386 1.3E-48 T 29-03-2018 SMALA_RS01925 90bd13fd99e653fc6673edf277cba649 396 SUPERFAMILY SSF46785 17 79 1.81E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS01925 90bd13fd99e653fc6673edf277cba649 396 ProSitePatterns PS01125 ROK family signature. 219 246 - T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 SMALA_RS01925 90bd13fd99e653fc6673edf277cba649 396 Gene3D G3DSA:3.30.420.40 82 204 5.8E-20 T 29-03-2018 SMALA_RS01925 90bd13fd99e653fc6673edf277cba649 396 Pfam PF13412 Winged helix-turn-helix DNA-binding 24 63 3.7E-6 T 29-03-2018 SMALA_RS01925 90bd13fd99e653fc6673edf277cba649 396 SUPERFAMILY SSF53067 90 383 1.83E-44 T 29-03-2018 SMALA_RS01925 90bd13fd99e653fc6673edf277cba649 396 Pfam PF00480 ROK family 137 382 1.6E-46 T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 SMALA_RS01925 90bd13fd99e653fc6673edf277cba649 396 Gene3D G3DSA:1.10.10.10 18 81 4.6E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS16475 1a9f5e376a2c3e632002958b1ed67dd7 388 Hamap MF_00540 Adenosine deaminase [add]. 12 357 55.929 T 29-03-2018 IPR028893 Adenosine deaminase GO:0004000|GO:0009168 KEGG: 00230+3.5.4.4|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-74217 SMALA_RS16475 1a9f5e376a2c3e632002958b1ed67dd7 388 Pfam PF00962 Adenosine/AMP deaminase 17 354 3.2E-86 T 29-03-2018 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 SMALA_RS16475 1a9f5e376a2c3e632002958b1ed67dd7 388 SUPERFAMILY SSF51556 13 351 7.26E-71 T 29-03-2018 IPR032466 Metal-dependent hydrolase SMALA_RS16475 1a9f5e376a2c3e632002958b1ed67dd7 388 Gene3D G3DSA:3.20.20.140 1 356 1.4E-79 T 29-03-2018 SMALA_RS16475 1a9f5e376a2c3e632002958b1ed67dd7 388 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 18 354 1.2E-71 T 29-03-2018 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 SMALA_RS11995 13911e813493b7f6fde7460e7732348e 876 SUPERFAMILY SSF49464 610 689 4.71E-13 T 29-03-2018 IPR008969 Carboxypeptidase-like, regulatory domain SMALA_RS11995 13911e813493b7f6fde7460e7732348e 876 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 33 447 3.1E-76 T 29-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 SMALA_RS11995 13911e813493b7f6fde7460e7732348e 876 Pfam PF13620 Carboxypeptidase regulatory-like domain 779 853 2.6E-13 T 29-03-2018 SMALA_RS11995 13911e813493b7f6fde7460e7732348e 876 Pfam PF13620 Carboxypeptidase regulatory-like domain 611 686 8.3E-13 T 29-03-2018 SMALA_RS11995 13911e813493b7f6fde7460e7732348e 876 Pfam PF13620 Carboxypeptidase regulatory-like domain 694 758 4.9E-11 T 29-03-2018 SMALA_RS11995 13911e813493b7f6fde7460e7732348e 876 Pfam PF07690 Major Facilitator Superfamily 37 436 2.4E-52 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS11995 13911e813493b7f6fde7460e7732348e 876 SUPERFAMILY SSF49478 694 759 3.92E-11 T 29-03-2018 SMALA_RS11995 13911e813493b7f6fde7460e7732348e 876 Gene3D G3DSA:2.60.40.1120 610 690 1.3E-12 T 29-03-2018 SMALA_RS11995 13911e813493b7f6fde7460e7732348e 876 Gene3D G3DSA:2.60.40.1120 778 873 6.6E-15 T 29-03-2018 SMALA_RS11995 13911e813493b7f6fde7460e7732348e 876 SUPERFAMILY SSF49478 779 846 1.45E-11 T 29-03-2018 SMALA_RS11995 13911e813493b7f6fde7460e7732348e 876 Gene3D G3DSA:1.20.1250.20 31 226 4.2E-33 T 29-03-2018 SMALA_RS11995 13911e813493b7f6fde7460e7732348e 876 Gene3D G3DSA:1.20.1250.20 277 562 1.5E-33 T 29-03-2018 SMALA_RS11995 13911e813493b7f6fde7460e7732348e 876 SUPERFAMILY SSF103473 523 547 3.92E-72 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS11995 13911e813493b7f6fde7460e7732348e 876 SUPERFAMILY SSF103473 273 446 3.92E-72 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS11995 13911e813493b7f6fde7460e7732348e 876 SUPERFAMILY SSF103473 1 223 3.92E-72 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS11995 13911e813493b7f6fde7460e7732348e 876 Gene3D G3DSA:2.60.40.1120 691 772 1.4E-11 T 29-03-2018 SMALA_RS16885 e2987c48005bea08e1ffb883165c2cc7 390 Gene3D G3DSA:3.30.1490.20 21 87 1.5E-21 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SMALA_RS16885 e2987c48005bea08e1ffb883165c2cc7 390 Hamap MF_00558 Succinate--CoA ligase [ADP-forming] subunit beta [sucC]. 1 389 37.722 T 29-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 SMALA_RS16885 e2987c48005bea08e1ffb883165c2cc7 390 SUPERFAMILY SSF52210 231 387 1.83E-41 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMALA_RS16885 e2987c48005bea08e1ffb883165c2cc7 390 Pfam PF00549 CoA-ligase 256 380 2.1E-13 T 29-03-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMALA_RS16885 e2987c48005bea08e1ffb883165c2cc7 390 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 2 388 7.5E-126 T 29-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 SMALA_RS16885 e2987c48005bea08e1ffb883165c2cc7 390 SUPERFAMILY SSF56059 3 226 9.3E-67 T 29-03-2018 SMALA_RS16885 e2987c48005bea08e1ffb883165c2cc7 390 Gene3D G3DSA:3.40.50.261 232 388 3.3E-35 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMALA_RS16885 e2987c48005bea08e1ffb883165c2cc7 390 Pfam PF08442 ATP-grasp domain 2 194 1.9E-68 T 29-03-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 SMALA_RS16885 e2987c48005bea08e1ffb883165c2cc7 390 Gene3D G3DSA:3.30.470.20 88 231 7.5E-50 T 29-03-2018 SMALA_RS16885 e2987c48005bea08e1ffb883165c2cc7 390 PIRSF PIRSF001554 1 390 2.5E-136 T 29-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 SMALA_RS16885 e2987c48005bea08e1ffb883165c2cc7 390 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 249 273 - T 29-03-2018 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMALA_RS05325 99d75564f5f4624f1b654ab50bb676d3 247 Pfam PF08713 DNA alkylation repair enzyme 13 235 5.0E-38 T 29-03-2018 IPR014825 DNA alkylation repair enzyme SMALA_RS05325 99d75564f5f4624f1b654ab50bb676d3 247 SUPERFAMILY SSF48371 14 236 5.42E-38 T 29-03-2018 IPR016024 Armadillo-type fold GO:0005488 SMALA_RS05325 99d75564f5f4624f1b654ab50bb676d3 247 Gene3D G3DSA:1.25.40.290 133 240 2.3E-18 T 29-03-2018 SMALA_RS05325 99d75564f5f4624f1b654ab50bb676d3 247 Gene3D G3DSA:1.20.1660.10 8 132 4.8E-18 T 29-03-2018 SMALA_RS14420 a5eedc8432c8d701891f4b3314395374 468 Pfam PF00232 Glycosyl hydrolase family 1 3 462 2.1E-158 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SMALA_RS14420 a5eedc8432c8d701891f4b3314395374 468 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 368 376 - T 29-03-2018 IPR018120 Glycoside hydrolase family 1, active site SMALA_RS14420 a5eedc8432c8d701891f4b3314395374 468 Gene3D G3DSA:3.20.20.80 2 468 1.3E-165 T 29-03-2018 SMALA_RS14420 a5eedc8432c8d701891f4b3314395374 468 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 9 23 - T 29-03-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site SMALA_RS14420 a5eedc8432c8d701891f4b3314395374 468 PRINTS PR00131 Glycosyl hydrolase family 1 signature 287 301 5.5E-23 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SMALA_RS14420 a5eedc8432c8d701891f4b3314395374 468 PRINTS PR00131 Glycosyl hydrolase family 1 signature 368 376 5.5E-23 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SMALA_RS14420 a5eedc8432c8d701891f4b3314395374 468 PRINTS PR00131 Glycosyl hydrolase family 1 signature 389 400 5.5E-23 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SMALA_RS14420 a5eedc8432c8d701891f4b3314395374 468 PRINTS PR00131 Glycosyl hydrolase family 1 signature 410 427 5.5E-23 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SMALA_RS14420 a5eedc8432c8d701891f4b3314395374 468 PRINTS PR00131 Glycosyl hydrolase family 1 signature 434 446 5.5E-23 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SMALA_RS14420 a5eedc8432c8d701891f4b3314395374 468 TIGRFAM TIGR03356 BGL: beta-galactosidase 5 456 7.0E-176 T 29-03-2018 IPR017736 Glycoside hydrolase, family 1, beta-glucosidase GO:0008422|GO:0030245 KEGG: 00460+3.2.1.21|KEGG: 00500+3.2.1.21|KEGG: 00940+3.2.1.21|MetaCyc: PWY-3121|MetaCyc: PWY-5176|MetaCyc: PWY-6002|MetaCyc: PWY-6788|MetaCyc: PWY-7091|MetaCyc: PWY-7092 SMALA_RS14420 a5eedc8432c8d701891f4b3314395374 468 SUPERFAMILY SSF51445 3 464 2.9E-160 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS04605 ba2dff6b3c582e0f0136a89f9a63d54a 312 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 43 293 1.3E-60 T 29-03-2018 SMALA_RS04605 ba2dff6b3c582e0f0136a89f9a63d54a 312 Gene3D G3DSA:3.40.190.10 140 235 4.9E-26 T 29-03-2018 SMALA_RS04605 ba2dff6b3c582e0f0136a89f9a63d54a 312 TIGRFAM TIGR01098 3A0109s03R: phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein 11 259 6.7E-63 T 29-03-2018 IPR005770 Phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein GO:0043190|GO:0055085 SMALA_RS04605 ba2dff6b3c582e0f0136a89f9a63d54a 312 SUPERFAMILY SSF53850 37 306 1.09E-44 T 29-03-2018 SMALA_RS04605 ba2dff6b3c582e0f0136a89f9a63d54a 312 Gene3D G3DSA:3.40.190.10 35 139 7.0E-8 T 29-03-2018 SMALA_RS00210 ff3fd772fbf3ccfb869c7d3efb44acf2 305 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 174 293 6.2E-36 T 29-03-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 SMALA_RS00210 ff3fd772fbf3ccfb869c7d3efb44acf2 305 PIRSF PIRSF000103 4 296 2.2E-69 T 29-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 SMALA_RS00210 ff3fd772fbf3ccfb869c7d3efb44acf2 305 SUPERFAMILY SSF48179 173 295 2.38E-36 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMALA_RS00210 ff3fd772fbf3ccfb869c7d3efb44acf2 305 Gene3D G3DSA:1.10.1040.10 183 297 1.9E-34 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMALA_RS00210 ff3fd772fbf3ccfb869c7d3efb44acf2 305 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 11 167 2.5E-40 T 29-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 SMALA_RS00210 ff3fd772fbf3ccfb869c7d3efb44acf2 305 Gene3D G3DSA:3.40.50.720 1 182 1.5E-33 T 29-03-2018 SMALA_RS00210 ff3fd772fbf3ccfb869c7d3efb44acf2 305 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 14 27 - T 29-03-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 SMALA_RS00210 ff3fd772fbf3ccfb869c7d3efb44acf2 305 SUPERFAMILY SSF51735 11 170 4.76E-40 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS12515 fcea9f4c74f9846c77f5ad15c09548f1 146 Pfam PF01047 MarR family 35 90 7.1E-12 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS12515 fcea9f4c74f9846c77f5ad15c09548f1 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 117 137 6.4E-8 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS12515 fcea9f4c74f9846c77f5ad15c09548f1 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 68 83 6.4E-8 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS12515 fcea9f4c74f9846c77f5ad15c09548f1 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 51 67 6.4E-8 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS12515 fcea9f4c74f9846c77f5ad15c09548f1 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 103 6.4E-8 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS12515 fcea9f4c74f9846c77f5ad15c09548f1 146 SUPERFAMILY SSF46785 7 144 5.1E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS12515 fcea9f4c74f9846c77f5ad15c09548f1 146 Gene3D G3DSA:1.10.10.10 3 146 3.5E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS12515 fcea9f4c74f9846c77f5ad15c09548f1 146 SMART SM00347 27 127 1.2E-14 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS42915 e3695de6ab8c4dca9f31c004ca7653c7 205 Gene3D G3DSA:3.30.70.250 134 186 4.8E-8 T 29-03-2018 SMALA_RS42915 e3695de6ab8c4dca9f31c004ca7653c7 205 SUPERFAMILY SSF52151 2 126 1.44E-28 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS42915 e3695de6ab8c4dca9f31c004ca7653c7 205 Gene3D G3DSA:3.40.366.10 1 133 2.5E-27 T 29-03-2018 SMALA_RS42915 e3695de6ab8c4dca9f31c004ca7653c7 205 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 4 202 9.3E-12 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS42915 e3695de6ab8c4dca9f31c004ca7653c7 205 Pfam PF00698 Acyl transferase domain 2 178 4.1E-35 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS42915 e3695de6ab8c4dca9f31c004ca7653c7 205 SUPERFAMILY SSF55048 126 184 1.83E-5 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS18920 e4d4e1fdefa1867a1d9ba46042127e73 388 SMART SM00387 298 388 0.0015 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS18920 e4d4e1fdefa1867a1d9ba46042127e73 388 Gene3D G3DSA:3.30.565.10 260 387 2.1E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS18920 e4d4e1fdefa1867a1d9ba46042127e73 388 Pfam PF13796 Putative sensor 15 129 2.9E-9 T 29-03-2018 IPR025828 Putative sensor domain SMALA_RS18920 e4d4e1fdefa1867a1d9ba46042127e73 388 Pfam PF07730 Histidine kinase 195 261 5.8E-15 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMALA_RS18920 e4d4e1fdefa1867a1d9ba46042127e73 388 SUPERFAMILY SSF55874 270 385 3.73E-14 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS23510 90e7245685f71770bab9719839a4305f 302 Gene3D G3DSA:3.20.20.30 13 290 1.9E-46 T 29-03-2018 SMALA_RS23510 90e7245685f71770bab9719839a4305f 302 Pfam PF00296 Luciferase-like monooxygenase 17 231 7.8E-29 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS23510 90e7245685f71770bab9719839a4305f 302 SUPERFAMILY SSF51679 1 284 2.75E-45 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS01160 aba4030e086c0f9cb130fb4b18e70fc8 312 Gene3D G3DSA:3.40.190.10 193 279 3.4E-19 T 29-03-2018 SMALA_RS01160 aba4030e086c0f9cb130fb4b18e70fc8 312 Pfam PF03466 LysR substrate binding domain 98 303 1.9E-30 T 29-03-2018 IPR005119 LysR, substrate-binding SMALA_RS01160 aba4030e086c0f9cb130fb4b18e70fc8 312 Gene3D G3DSA:3.40.190.10 99 192 6.0E-18 T 29-03-2018 SMALA_RS01160 aba4030e086c0f9cb130fb4b18e70fc8 312 SUPERFAMILY SSF53850 100 304 7.14E-29 T 29-03-2018 SMALA_RS01160 aba4030e086c0f9cb130fb4b18e70fc8 312 Gene3D G3DSA:1.10.10.10 9 93 4.3E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS01160 aba4030e086c0f9cb130fb4b18e70fc8 312 SUPERFAMILY SSF46785 9 121 4.08E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS01160 aba4030e086c0f9cb130fb4b18e70fc8 312 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 13 71 3.9E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS40880 cd2850ed854949f603c96ebb5954fa03 339 SUPERFAMILY SSF53474 36 145 1.84E-17 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS40880 cd2850ed854949f603c96ebb5954fa03 339 Gene3D G3DSA:3.40.50.1820 34 313 1.2E-30 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS40880 cd2850ed854949f603c96ebb5954fa03 339 SUPERFAMILY SSF53474 288 337 3.73E-43 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS40880 cd2850ed854949f603c96ebb5954fa03 339 SUPERFAMILY SSF53474 146 261 3.73E-43 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS40880 cd2850ed854949f603c96ebb5954fa03 339 TIGRFAM TIGR01840 esterase_phb: esterase, PHB depolymerase family 61 270 6.0E-65 T 29-03-2018 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 SMALA_RS40880 cd2850ed854949f603c96ebb5954fa03 339 Pfam PF10503 Esterase PHB depolymerase 63 264 3.6E-36 T 29-03-2018 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 SMALA_RS11600 e1676d09fc748078f7a3b246ffa66241 248 SUPERFAMILY SSF47384 18 75 1.22E-8 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS11600 e1676d09fc748078f7a3b246ffa66241 248 Gene3D G3DSA:1.10.287.130 9 76 4.3E-6 T 29-03-2018 SMALA_RS11600 e1676d09fc748078f7a3b246ffa66241 248 SMART SM00387 126 240 2.3E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS11600 e1676d09fc748078f7a3b246ffa66241 248 SUPERFAMILY SSF55874 86 238 8.25E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS11600 e1676d09fc748078f7a3b246ffa66241 248 Pfam PF00512 His Kinase A (phospho-acceptor) domain 22 75 6.9E-7 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS11600 e1676d09fc748078f7a3b246ffa66241 248 PRINTS PR00344 Bacterial sensor protein C-terminal signature 169 183 7.4E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS11600 e1676d09fc748078f7a3b246ffa66241 248 PRINTS PR00344 Bacterial sensor protein C-terminal signature 224 237 7.4E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS11600 e1676d09fc748078f7a3b246ffa66241 248 PRINTS PR00344 Bacterial sensor protein C-terminal signature 200 218 7.4E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS11600 e1676d09fc748078f7a3b246ffa66241 248 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 127 237 6.9E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS11600 e1676d09fc748078f7a3b246ffa66241 248 Gene3D G3DSA:3.30.565.10 87 248 1.1E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS37150 b34fb19ced50d4751ba60a19e496672b 1087 SMART SM00926 44 98 1.4E-22 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS37150 b34fb19ced50d4751ba60a19e496672b 1087 Pfam PF00384 Molybdopterin oxidoreductase 160 616 2.3E-21 T 29-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS37150 b34fb19ced50d4751ba60a19e496672b 1087 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 45 94 1.7E-19 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS37150 b34fb19ced50d4751ba60a19e496672b 1087 Gene3D G3DSA:3.40.50.740 517 691 3.5E-22 T 29-03-2018 SMALA_RS37150 b34fb19ced50d4751ba60a19e496672b 1087 Gene3D G3DSA:3.40.228.10 782 874 4.6E-14 T 29-03-2018 SMALA_RS37150 b34fb19ced50d4751ba60a19e496672b 1087 Pfam PF01568 Molydopterin dinucleotide binding domain 931 1048 4.1E-10 T 29-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 SMALA_RS37150 b34fb19ced50d4751ba60a19e496672b 1087 Gene3D G3DSA:2.40.40.20 875 1056 4.7E-29 T 29-03-2018 SMALA_RS37150 b34fb19ced50d4751ba60a19e496672b 1087 SUPERFAMILY SSF50692 926 1055 2.49E-33 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain SMALA_RS37150 b34fb19ced50d4751ba60a19e496672b 1087 SUPERFAMILY SSF50692 865 894 2.49E-33 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain SMALA_RS37150 b34fb19ced50d4751ba60a19e496672b 1087 Gene3D G3DSA:2.20.25.90 39 99 1.4E-22 T 29-03-2018 SMALA_RS37150 b34fb19ced50d4751ba60a19e496672b 1087 Gene3D G3DSA:3.40.228.10 185 516 2.1E-75 T 29-03-2018 SMALA_RS37150 b34fb19ced50d4751ba60a19e496672b 1087 SUPERFAMILY SSF53706 42 344 3.8E-249 T 29-03-2018 SMALA_RS37150 b34fb19ced50d4751ba60a19e496672b 1087 SUPERFAMILY SSF53706 383 885 3.8E-249 T 29-03-2018 SMALA_RS20330 1c8965d7c9994615adf624ebdd8071b3 124 Pfam PF00376 MerR family regulatory protein 1 35 9.0E-9 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS20330 1c8965d7c9994615adf624ebdd8071b3 124 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 59 122 8.1E-17 T 29-03-2018 IPR004606 Molybdenum-pterin binding GO:0006810|GO:0030151 SMALA_RS20330 1c8965d7c9994615adf624ebdd8071b3 124 Pfam PF03459 TOBE domain 59 119 3.4E-14 T 29-03-2018 IPR005116 Transport-associated OB, type 1 SMALA_RS20330 1c8965d7c9994615adf624ebdd8071b3 124 SUPERFAMILY SSF50331 9 121 3.16E-18 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal SMALA_RS20330 1c8965d7c9994615adf624ebdd8071b3 124 Gene3D G3DSA:2.40.50.100 55 118 1.8E-19 T 29-03-2018 SMALA_RS20330 1c8965d7c9994615adf624ebdd8071b3 124 Gene3D G3DSA:1.10.1660.10 1 54 2.3E-7 T 29-03-2018 SMALA_RS20330 1c8965d7c9994615adf624ebdd8071b3 124 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 1 34 2.3E-7 T 29-03-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 SMALA_RS40765 44973246df47a76f4c3e58bc6576b2c1 458 PIRSF PIRSF000337 3 450 1.0E-135 T 29-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 SMALA_RS40765 44973246df47a76f4c3e58bc6576b2c1 458 Gene3D G3DSA:3.20.20.30 4 457 1.6E-98 T 29-03-2018 SMALA_RS40765 44973246df47a76f4c3e58bc6576b2c1 458 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 15 435 1.3E-135 T 29-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 SMALA_RS40765 44973246df47a76f4c3e58bc6576b2c1 458 SUPERFAMILY SSF51679 5 441 3.27E-116 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS40765 44973246df47a76f4c3e58bc6576b2c1 458 Pfam PF00296 Luciferase-like monooxygenase 24 321 7.1E-57 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS13675 d4714a8c88cd52fc1ce37c7b74601dcc 304 SUPERFAMILY SSF53474 17 301 2.18E-69 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS13675 d4714a8c88cd52fc1ce37c7b74601dcc 304 Pfam PF12697 Alpha/beta hydrolase family 45 295 1.5E-18 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS13675 d4714a8c88cd52fc1ce37c7b74601dcc 304 PRINTS PR00412 Epoxide hydrolase signature 277 299 1.1E-9 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS13675 d4714a8c88cd52fc1ce37c7b74601dcc 304 PRINTS PR00412 Epoxide hydrolase signature 112 125 1.1E-9 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS13675 d4714a8c88cd52fc1ce37c7b74601dcc 304 PRINTS PR00412 Epoxide hydrolase signature 49 67 1.1E-9 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS13675 d4714a8c88cd52fc1ce37c7b74601dcc 304 Gene3D G3DSA:3.40.50.1820 19 301 3.7E-48 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS00390 53e1689f7a8f138087e245b44c201079 316 SUPERFAMILY SSF52518 9 305 7.23E-64 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold SMALA_RS00390 53e1689f7a8f138087e245b44c201079 316 Pfam PF00676 Dehydrogenase E1 component 26 267 8.3E-45 T 29-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 SMALA_RS00390 53e1689f7a8f138087e245b44c201079 316 Gene3D G3DSA:3.40.50.970 9 311 2.5E-52 T 29-03-2018 SMALA_RS04945 28b2c29150a5e31c395aa98e593c3fdb 307 Gene3D G3DSA:1.10.1740.10 3 69 1.2E-11 T 29-03-2018 SMALA_RS04945 28b2c29150a5e31c395aa98e593c3fdb 307 Pfam PF08281 Sigma-70, region 4 105 156 2.0E-11 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS04945 28b2c29150a5e31c395aa98e593c3fdb 307 SUPERFAMILY SSF88946 7 78 9.02E-11 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS04945 28b2c29150a5e31c395aa98e593c3fdb 307 SUPERFAMILY SSF54427 168 283 4.17E-13 T 29-03-2018 IPR032710 NTF2-like domain SMALA_RS04945 28b2c29150a5e31c395aa98e593c3fdb 307 Gene3D G3DSA:3.10.450.50 148 286 1.2E-21 T 29-03-2018 SMALA_RS04945 28b2c29150a5e31c395aa98e593c3fdb 307 Pfam PF04542 Sigma-70 region 2 7 69 1.3E-10 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS04945 28b2c29150a5e31c395aa98e593c3fdb 307 Gene3D G3DSA:1.10.10.10 70 147 1.6E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS04945 28b2c29150a5e31c395aa98e593c3fdb 307 TIGRFAM TIGR02957 SigX4: RNA polymerase sigma-70 factor, TIGR02957 family 5 286 6.5E-109 T 29-03-2018 IPR014303 RNA polymerase sigma-70, ECF type SMALA_RS04945 28b2c29150a5e31c395aa98e593c3fdb 307 SUPERFAMILY SSF88659 80 157 3.18E-10 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS04945 28b2c29150a5e31c395aa98e593c3fdb 307 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 7 156 9.1E-14 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS28140 701ca7b2aaf917fe3974773d9b6fb12a 79 Hamap MF_00088 UPF0109 protein . 2 73 21.623 T 29-03-2018 IPR020627 Uncharacterised protein family UPF0109 SMALA_RS28140 701ca7b2aaf917fe3974773d9b6fb12a 79 Pfam PF13083 KH domain 3 64 4.5E-19 T 29-03-2018 SMALA_RS28140 701ca7b2aaf917fe3974773d9b6fb12a 79 SUPERFAMILY SSF54814 16 62 2.16E-8 T 29-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 SMALA_RS28140 701ca7b2aaf917fe3974773d9b6fb12a 79 Gene3D G3DSA:3.30.300.20 1 76 2.4E-14 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta SMALA_RS11540 af929cf9e1767efdc4c1941336be538c 109 SUPERFAMILY SSF54909 4 104 1.42E-25 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel SMALA_RS11540 af929cf9e1767efdc4c1941336be538c 109 Pfam PF03992 Antibiotic biosynthesis monooxygenase 4 77 2.6E-17 T 29-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain SMALA_RS11540 af929cf9e1767efdc4c1941336be538c 109 Gene3D G3DSA:3.30.70.100 2 109 2.4E-34 T 29-03-2018 SMALA_RS29630 387d5d11956b32fd664014db37753645 409 PRINTS PR01466 Bacterial arginine deiminase signature 386 404 6.0E-47 T 29-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 SMALA_RS29630 387d5d11956b32fd664014db37753645 409 PRINTS PR01466 Bacterial arginine deiminase signature 343 360 6.0E-47 T 29-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 SMALA_RS29630 387d5d11956b32fd664014db37753645 409 PRINTS PR01466 Bacterial arginine deiminase signature 151 169 6.0E-47 T 29-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 SMALA_RS29630 387d5d11956b32fd664014db37753645 409 PRINTS PR01466 Bacterial arginine deiminase signature 1 20 6.0E-47 T 29-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 SMALA_RS29630 387d5d11956b32fd664014db37753645 409 PRINTS PR01466 Bacterial arginine deiminase signature 363 377 6.0E-47 T 29-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 SMALA_RS29630 387d5d11956b32fd664014db37753645 409 PRINTS PR01466 Bacterial arginine deiminase signature 179 194 6.0E-47 T 29-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 SMALA_RS29630 387d5d11956b32fd664014db37753645 409 Gene3D G3DSA:3.75.10.10 2 405 1.4E-101 T 29-03-2018 SMALA_RS29630 387d5d11956b32fd664014db37753645 409 Pfam PF02274 Amidinotransferase 17 404 1.1E-93 T 29-03-2018 SMALA_RS29630 387d5d11956b32fd664014db37753645 409 SUPERFAMILY SSF55909 2 407 2.36E-125 T 29-03-2018 SMALA_RS29630 387d5d11956b32fd664014db37753645 409 Hamap MF_00242 Arginine deiminase [arcA]. 1 407 42.203 T 29-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 SMALA_RS29630 387d5d11956b32fd664014db37753645 409 PIRSF PIRSF006356 1 407 1.0E-148 T 29-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 SMALA_RS38330 5c24805e2f145ac87d96e0ff7720ee4d 335 Gene3D G3DSA:3.20.20.100 15 331 3.9E-88 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS38330 5c24805e2f145ac87d96e0ff7720ee4d 335 Pfam PF00248 Aldo/keto reductase family 28 327 4.1E-67 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS38330 5c24805e2f145ac87d96e0ff7720ee4d 335 SUPERFAMILY SSF51430 13 327 3.4E-92 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS17255 4ff0cfa2a1ba515be4de7748f1d20753 415 Pfam PF00144 Beta-lactamase 94 390 8.3E-48 T 29-03-2018 IPR001466 Beta-lactamase-related SMALA_RS17255 4ff0cfa2a1ba515be4de7748f1d20753 415 Gene3D G3DSA:3.40.710.10 38 413 7.3E-65 T 29-03-2018 SMALA_RS17255 4ff0cfa2a1ba515be4de7748f1d20753 415 SUPERFAMILY SSF56601 55 388 7.57E-65 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMALA_RS43210 9c6f8f39fe479ba7f60a828505261f21 171 Gene3D G3DSA:3.90.75.10 11 151 5.3E-13 T 29-03-2018 SMALA_RS43210 9c6f8f39fe479ba7f60a828505261f21 171 SUPERFAMILY SSF54060 55 122 1.35E-5 T 29-03-2018 SMALA_RS13280 d836a74499cc5ad6be6d8c34d60f0c4f 271 Pfam PF06827 Zinc finger found in FPG and IleRS 240 268 3.5E-7 T 29-03-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 SMALA_RS13280 d836a74499cc5ad6be6d8c34d60f0c4f 271 Gene3D G3DSA:3.20.190.10 1 116 2.0E-23 T 29-03-2018 SMALA_RS13280 d836a74499cc5ad6be6d8c34d60f0c4f 271 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 122 205 1.6E-19 T 29-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 SMALA_RS13280 d836a74499cc5ad6be6d8c34d60f0c4f 271 SMART SM00898 2 108 9.3E-20 T 29-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 SMALA_RS13280 d836a74499cc5ad6be6d8c34d60f0c4f 271 SUPERFAMILY SSF57716 220 267 2.02E-13 T 29-03-2018 SMALA_RS13280 d836a74499cc5ad6be6d8c34d60f0c4f 271 SUPERFAMILY SSF46946 121 205 7.51E-24 T 29-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 SMALA_RS13280 d836a74499cc5ad6be6d8c34d60f0c4f 271 ProSitePatterns PS01242 Zinc finger FPG-type signature. 243 267 - T 29-03-2018 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 SMALA_RS13280 d836a74499cc5ad6be6d8c34d60f0c4f 271 SMART SM01232 122 214 4.6E-33 T 29-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 SMALA_RS13280 d836a74499cc5ad6be6d8c34d60f0c4f 271 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 94 1.4E-7 T 29-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 SMALA_RS13280 d836a74499cc5ad6be6d8c34d60f0c4f 271 Gene3D G3DSA:1.10.8.50 117 268 2.7E-47 T 29-03-2018 SMALA_RS13280 d836a74499cc5ad6be6d8c34d60f0c4f 271 SUPERFAMILY SSF81624 2 123 7.46E-23 T 29-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 SMALA_RS08410 cdb2adc2dfe50a3664dda5d41d37f29c 356 ProSitePatterns PS00356 LacI-type HTH domain signature. 27 45 - T 29-03-2018 SMALA_RS08410 cdb2adc2dfe50a3664dda5d41d37f29c 356 SUPERFAMILY SSF47413 27 82 3.3E-18 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS08410 cdb2adc2dfe50a3664dda5d41d37f29c 356 Gene3D G3DSA:3.40.50.2300 189 352 4.4E-50 T 29-03-2018 SMALA_RS08410 cdb2adc2dfe50a3664dda5d41d37f29c 356 Pfam PF13377 Periplasmic binding protein-like domain 191 349 3.1E-38 T 29-03-2018 SMALA_RS08410 cdb2adc2dfe50a3664dda5d41d37f29c 356 SUPERFAMILY SSF53822 83 353 1.51E-60 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SMALA_RS08410 cdb2adc2dfe50a3664dda5d41d37f29c 356 Gene3D G3DSA:1.10.10.10 12 40 0.05 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS08410 cdb2adc2dfe50a3664dda5d41d37f29c 356 SMART SM00354 24 94 2.4E-29 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS08410 cdb2adc2dfe50a3664dda5d41d37f29c 356 Gene3D G3DSA:1.10.260.40 41 80 2.5E-26 T 29-03-2018 SMALA_RS08410 cdb2adc2dfe50a3664dda5d41d37f29c 356 Pfam PF00356 Bacterial regulatory proteins, lacI family 27 70 9.5E-20 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS08410 cdb2adc2dfe50a3664dda5d41d37f29c 356 Gene3D G3DSA:3.40.50.2300 81 188 3.8E-23 T 29-03-2018 SMALA_RS40585 29bd072908e64517a869137332aebd5d 316 SUPERFAMILY SSF161098 89 298 7.33E-19 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS40585 29bd072908e64517a869137332aebd5d 316 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 312 3.0E-31 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS40585 29bd072908e64517a869137332aebd5d 316 Gene3D G3DSA:1.10.3720.10 3 302 4.9E-37 T 29-03-2018 SMALA_RS28785 08e2921b68c1eff575faa58f5ee2ad1d 283 Gene3D G3DSA:1.10.10.60 152 227 2.4E-11 T 29-03-2018 SMALA_RS28785 08e2921b68c1eff575faa58f5ee2ad1d 283 Pfam PF02311 AraC-like ligand binding domain 16 144 7.1E-24 T 29-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 SMALA_RS28785 08e2921b68c1eff575faa58f5ee2ad1d 283 Gene3D G3DSA:2.60.120.280 16 151 7.1E-12 T 29-03-2018 SMALA_RS28785 08e2921b68c1eff575faa58f5ee2ad1d 283 Gene3D G3DSA:1.10.10.60 228 281 5.3E-16 T 29-03-2018 SMALA_RS28785 08e2921b68c1eff575faa58f5ee2ad1d 283 SUPERFAMILY SSF51215 29 153 3.01E-19 T 29-03-2018 SMALA_RS28785 08e2921b68c1eff575faa58f5ee2ad1d 283 SUPERFAMILY SSF46689 223 271 2.9E-10 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS28785 08e2921b68c1eff575faa58f5ee2ad1d 283 Pfam PF12833 Helix-turn-helix domain 192 269 8.4E-23 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS28785 08e2921b68c1eff575faa58f5ee2ad1d 283 SMART SM00342 186 268 3.0E-28 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS28785 08e2921b68c1eff575faa58f5ee2ad1d 283 SUPERFAMILY SSF46689 172 220 1.34E-7 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS07365 df170827671b2ebedf71a0d74fe20177 223 SMART SM00895 92 214 1.3E-22 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS07365 df170827671b2ebedf71a0d74fe20177 223 Pfam PF07729 FCD domain 92 213 2.2E-27 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS07365 df170827671b2ebedf71a0d74fe20177 223 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 56 2.1E-5 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS07365 df170827671b2ebedf71a0d74fe20177 223 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 26 40 2.1E-5 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS07365 df170827671b2ebedf71a0d74fe20177 223 Pfam PF00392 Bacterial regulatory proteins, gntR family 5 66 9.8E-18 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS07365 df170827671b2ebedf71a0d74fe20177 223 SUPERFAMILY SSF46785 4 70 1.15E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS07365 df170827671b2ebedf71a0d74fe20177 223 SMART SM00345 7 66 1.4E-14 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS07365 df170827671b2ebedf71a0d74fe20177 223 Gene3D G3DSA:1.10.10.10 2 68 1.6E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS07365 df170827671b2ebedf71a0d74fe20177 223 SUPERFAMILY SSF48008 89 221 9.15E-29 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS07365 df170827671b2ebedf71a0d74fe20177 223 Gene3D G3DSA:1.20.120.530 71 223 7.5E-34 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS08500 47da580cb71b55c0ee15fcd0049430a8 1195 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 4 1081 1.5E-154 T 29-03-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMALA_RS08500 47da580cb71b55c0ee15fcd0049430a8 1195 Pfam PF14579 Helix-hairpin-helix motif 837 956 1.8E-18 T 29-03-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMALA_RS08500 47da580cb71b55c0ee15fcd0049430a8 1195 Pfam PF02811 PHP domain 6 123 2.3E-13 T 29-03-2018 IPR004013 PHP domain GO:0003824 SMALA_RS08500 47da580cb71b55c0ee15fcd0049430a8 1195 Gene3D G3DSA:3.20.20.140 3 286 3.6E-27 T 29-03-2018 SMALA_RS08500 47da580cb71b55c0ee15fcd0049430a8 1195 Gene3D G3DSA:2.40.50.140 1031 1122 6.5E-4 T 29-03-2018 SMALA_RS08500 47da580cb71b55c0ee15fcd0049430a8 1195 SUPERFAMILY SSF89550 6 73 3.14E-8 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 SMALA_RS08500 47da580cb71b55c0ee15fcd0049430a8 1195 SMART SM00481 5 72 8.1E-19 T 29-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal SMALA_RS08500 47da580cb71b55c0ee15fcd0049430a8 1195 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 353 763 1.4E-122 T 29-03-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMALA_RS21765 179c1022f434d2e1176276201e96e1de 406 SUPERFAMILY SSF103473 5 388 1.44E-30 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS21765 179c1022f434d2e1176276201e96e1de 406 Pfam PF07690 Major Facilitator Superfamily 218 382 1.0E-9 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS21765 179c1022f434d2e1176276201e96e1de 406 Gene3D G3DSA:1.20.1250.20 8 192 9.5E-10 T 29-03-2018 SMALA_RS21765 179c1022f434d2e1176276201e96e1de 406 Gene3D G3DSA:1.20.1250.20 206 386 1.6E-19 T 29-03-2018 SMALA_RS30270 174d7d08c7558086c4f3efeeb124e791 233 PIRSF PIRSF000857 2 233 2.8E-91 T 29-03-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 SMALA_RS30270 174d7d08c7558086c4f3efeeb124e791 233 Gene3D G3DSA:3.40.50.620 5 233 5.4E-46 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS30270 174d7d08c7558086c4f3efeeb124e791 233 TIGRFAM TIGR00434 cysH: phosophoadenylyl-sulfate reductase 27 232 1.2E-57 T 29-03-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 SMALA_RS30270 174d7d08c7558086c4f3efeeb124e791 233 SUPERFAMILY SSF52402 18 194 2.13E-48 T 29-03-2018 SMALA_RS30270 174d7d08c7558086c4f3efeeb124e791 233 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 46 208 2.7E-42 T 29-03-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 SMALA_RS28125 aa739890cdeff6bcb76a7348d63a5ca2 471 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 103 271 1.2E-12 T 29-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMALA_RS28125 aa739890cdeff6bcb76a7348d63a5ca2 471 Gene3D G3DSA:3.40.50.800 283 409 4.3E-29 T 29-03-2018 IPR004154 Anticodon-binding SMALA_RS28125 aa739890cdeff6bcb76a7348d63a5ca2 471 Pfam PF03129 Anticodon binding domain 290 375 7.3E-12 T 29-03-2018 IPR004154 Anticodon-binding SMALA_RS28125 aa739890cdeff6bcb76a7348d63a5ca2 471 PRINTS PR01046 Prolyl-tRNA synthetase signature 106 117 2.5E-5 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 SMALA_RS28125 aa739890cdeff6bcb76a7348d63a5ca2 471 PRINTS PR01046 Prolyl-tRNA synthetase signature 145 156 2.5E-5 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 SMALA_RS28125 aa739890cdeff6bcb76a7348d63a5ca2 471 PRINTS PR01046 Prolyl-tRNA synthetase signature 65 83 2.5E-5 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 SMALA_RS28125 aa739890cdeff6bcb76a7348d63a5ca2 471 PRINTS PR01046 Prolyl-tRNA synthetase signature 136 144 2.5E-5 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 SMALA_RS28125 aa739890cdeff6bcb76a7348d63a5ca2 471 SMART SM00946 409 471 4.2E-4 T 29-03-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 SMALA_RS28125 aa739890cdeff6bcb76a7348d63a5ca2 471 SUPERFAMILY SSF52954 278 399 4.09E-26 T 29-03-2018 IPR004154 Anticodon-binding SMALA_RS28125 aa739890cdeff6bcb76a7348d63a5ca2 471 Hamap MF_01571 Proline--tRNA ligase [proS]. 7 471 39.773 T 29-03-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 SMALA_RS28125 aa739890cdeff6bcb76a7348d63a5ca2 471 TIGRFAM TIGR00408 proS_fam_I: proline--tRNA ligase 10 417 1.7E-141 T 29-03-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 SMALA_RS28125 aa739890cdeff6bcb76a7348d63a5ca2 471 SUPERFAMILY SSF55681 12 277 2.17E-72 T 29-03-2018 SMALA_RS28125 aa739890cdeff6bcb76a7348d63a5ca2 471 Gene3D G3DSA:3.30.930.10 7 282 3.8E-59 T 29-03-2018 SMALA_RS22110 345588ae5516f9cc10dc73ae5628ead7 184 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 11 153 1.0E-68 T 29-03-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS22110 345588ae5516f9cc10dc73ae5628ead7 184 SUPERFAMILY SSF56770 9 154 2.09E-64 T 29-03-2018 SMALA_RS22110 345588ae5516f9cc10dc73ae5628ead7 184 ProSitePatterns PS01150 Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. 118 134 - T 29-03-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS22110 345588ae5516f9cc10dc73ae5628ead7 184 Gene3D G3DSA:3.40.50.700 11 173 1.7E-42 T 29-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS22110 345588ae5516f9cc10dc73ae5628ead7 184 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 1 151 41.648 T 29-03-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS22110 345588ae5516f9cc10dc73ae5628ead7 184 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 37 145 3.0E-24 T 29-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS31425 2dcad68ba1ae025a892c60ddeff17dca 711 Gene3D G3DSA:3.40.50.261 542 708 8.3E-29 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMALA_RS31425 2dcad68ba1ae025a892c60ddeff17dca 711 Gene3D G3DSA:3.40.50.720 255 376 3.3E-40 T 29-03-2018 SMALA_RS31425 2dcad68ba1ae025a892c60ddeff17dca 711 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 402 539 1.0E-49 T 29-03-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain SMALA_RS31425 2dcad68ba1ae025a892c60ddeff17dca 711 Gene3D G3DSA:3.40.50.261 377 541 1.5E-34 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMALA_RS31425 2dcad68ba1ae025a892c60ddeff17dca 711 SMART SM00881 258 353 2.3E-35 T 29-03-2018 IPR003781 CoA-binding GO:0048037 SMALA_RS31425 2dcad68ba1ae025a892c60ddeff17dca 711 SUPERFAMILY SSF52210 545 691 1.96E-28 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMALA_RS31425 2dcad68ba1ae025a892c60ddeff17dca 711 SUPERFAMILY SSF52210 380 542 6.67E-38 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMALA_RS31425 2dcad68ba1ae025a892c60ddeff17dca 711 Gene3D G3DSA:3.30.1490.20 56 104 9.2E-30 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SMALA_RS31425 2dcad68ba1ae025a892c60ddeff17dca 711 SUPERFAMILY SSF56059 26 241 4.84E-42 T 29-03-2018 SMALA_RS31425 2dcad68ba1ae025a892c60ddeff17dca 711 Pfam PF13380 CoA binding domain 262 380 2.4E-23 T 29-03-2018 IPR003781 CoA-binding GO:0048037 SMALA_RS31425 2dcad68ba1ae025a892c60ddeff17dca 711 Gene3D G3DSA:3.40.50.261 4 55 0.066 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMALA_RS31425 2dcad68ba1ae025a892c60ddeff17dca 711 Gene3D G3DSA:3.30.470.20 105 254 1.5E-31 T 29-03-2018 SMALA_RS31425 2dcad68ba1ae025a892c60ddeff17dca 711 Pfam PF13549 ATP-grasp domain 15 233 3.1E-79 T 29-03-2018 SMALA_RS31425 2dcad68ba1ae025a892c60ddeff17dca 711 SUPERFAMILY SSF51735 255 390 2.63E-37 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS05600 dc82d01b2a3c236c900fc0c0836f9888 125 Gene3D G3DSA:1.10.10.10 5 60 7.8E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS05600 dc82d01b2a3c236c900fc0c0836f9888 125 Gene3D G3DSA:3.10.450.50 61 124 4.4E-4 T 29-03-2018 SMALA_RS05600 dc82d01b2a3c236c900fc0c0836f9888 125 SUPERFAMILY SSF46785 17 122 1.44E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS05600 dc82d01b2a3c236c900fc0c0836f9888 125 Pfam PF03965 Penicillinase repressor 15 122 4.1E-19 T 29-03-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 SMALA_RS31260 35264ce6f038a33507e734fef90993f2 368 PIRSF PIRSF026166 13 344 4.0E-126 T 29-03-2018 IPR016833 Putative sodium bile acid cotransporter SMALA_RS31260 35264ce6f038a33507e734fef90993f2 368 Pfam PF13593 SBF-like CPA transporter family (DUF4137) 25 330 1.3E-92 T 29-03-2018 IPR016833 Putative sodium bile acid cotransporter SMALA_RS17475 2a3db523506ef1fa4807e2c86910b0a3 219 Pfam PF00072 Response regulator receiver domain 9 120 3.9E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS17475 2a3db523506ef1fa4807e2c86910b0a3 219 Pfam PF00196 Bacterial regulatory proteins, luxR family 157 211 4.1E-17 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS17475 2a3db523506ef1fa4807e2c86910b0a3 219 Gene3D G3DSA:1.10.10.10 132 219 9.0E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS17475 2a3db523506ef1fa4807e2c86910b0a3 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 187 199 3.8E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS17475 2a3db523506ef1fa4807e2c86910b0a3 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 157 171 3.8E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS17475 2a3db523506ef1fa4807e2c86910b0a3 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 171 187 3.8E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS17475 2a3db523506ef1fa4807e2c86910b0a3 219 ProSitePatterns PS00622 LuxR-type HTH domain signature. 171 198 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS17475 2a3db523506ef1fa4807e2c86910b0a3 219 SMART SM00421 154 211 5.2E-22 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS17475 2a3db523506ef1fa4807e2c86910b0a3 219 SUPERFAMILY SSF52172 7 132 1.24E-34 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS17475 2a3db523506ef1fa4807e2c86910b0a3 219 SUPERFAMILY SSF46894 152 218 1.29E-20 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS17475 2a3db523506ef1fa4807e2c86910b0a3 219 Gene3D G3DSA:3.40.50.2300 6 131 6.5E-38 T 29-03-2018 SMALA_RS17475 2a3db523506ef1fa4807e2c86910b0a3 219 SMART SM00448 7 120 4.9E-33 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS38065 ccf33b1b3b9940fed390ded347266ba5 336 Gene3D G3DSA:1.10.4080.10 2 332 1.4E-71 T 29-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 SMALA_RS38065 ccf33b1b3b9940fed390ded347266ba5 336 SUPERFAMILY SSF101478 3 329 1.96E-66 T 29-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 SMALA_RS38065 ccf33b1b3b9940fed390ded347266ba5 336 Pfam PF03747 ADP-ribosylglycohydrolase 10 306 9.5E-60 T 29-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 SMALA_RS03760 3b6a7fac9df162e0a2fb937292fd4f11 330 SUPERFAMILY SSF82549 11 329 3.66E-117 T 29-03-2018 SMALA_RS03760 3b6a7fac9df162e0a2fb937292fd4f11 330 Pfam PF02733 Dak1 domain 17 324 2.5E-125 T 29-03-2018 IPR004006 DhaK domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 SMALA_RS03760 3b6a7fac9df162e0a2fb937292fd4f11 330 TIGRFAM TIGR02363 dhaK1: dihydroxyacetone kinase, DhaK subunit 1 325 6.7E-147 T 29-03-2018 IPR012736 Dihydroxyacetone kinase DhaK, subunit 1 SMALA_RS03760 3b6a7fac9df162e0a2fb937292fd4f11 330 Gene3D G3DSA:3.40.50.10440 11 183 3.3E-71 T 29-03-2018 SMALA_RS03760 3b6a7fac9df162e0a2fb937292fd4f11 330 Gene3D G3DSA:3.30.1180.20 184 330 6.2E-48 T 29-03-2018 SMALA_RS12950 974833c1b437afc661a7ae368213919e 378 Pfam PF00226 DnaJ domain 4 65 4.3E-26 T 29-03-2018 IPR001623 DnaJ domain SMALA_RS12950 974833c1b437afc661a7ae368213919e 378 SMART SM00271 3 60 5.8E-31 T 29-03-2018 IPR001623 DnaJ domain SMALA_RS12950 974833c1b437afc661a7ae368213919e 378 PRINTS PR00625 DnaJ domain signature 24 39 6.3E-24 T 29-03-2018 IPR001623 DnaJ domain SMALA_RS12950 974833c1b437afc661a7ae368213919e 378 PRINTS PR00625 DnaJ domain signature 40 60 6.3E-24 T 29-03-2018 IPR001623 DnaJ domain SMALA_RS12950 974833c1b437afc661a7ae368213919e 378 PRINTS PR00625 DnaJ domain signature 60 79 6.3E-24 T 29-03-2018 IPR001623 DnaJ domain SMALA_RS12950 974833c1b437afc661a7ae368213919e 378 PRINTS PR00625 DnaJ domain signature 6 24 6.3E-24 T 29-03-2018 IPR001623 DnaJ domain SMALA_RS12950 974833c1b437afc661a7ae368213919e 378 Gene3D G3DSA:2.10.230.10 140 206 2.9E-16 T 29-03-2018 SMALA_RS12950 974833c1b437afc661a7ae368213919e 378 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 4 349 5.4E-118 T 29-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 SMALA_RS12950 974833c1b437afc661a7ae368213919e 378 Gene3D G3DSA:2.60.260.20 207 254 4.4E-11 T 29-03-2018 SMALA_RS12950 974833c1b437afc661a7ae368213919e 378 ProSitePatterns PS00636 Nt-dnaJ domain signature. 45 64 - T 29-03-2018 IPR018253 DnaJ domain, conserved site SMALA_RS12950 974833c1b437afc661a7ae368213919e 378 SUPERFAMILY SSF49493 213 257 5.76E-20 T 29-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 SMALA_RS12950 974833c1b437afc661a7ae368213919e 378 SUPERFAMILY SSF49493 115 148 5.76E-20 T 29-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 SMALA_RS12950 974833c1b437afc661a7ae368213919e 378 Gene3D G3DSA:1.10.287.110 1 111 1.8E-34 T 29-03-2018 IPR001623 DnaJ domain SMALA_RS12950 974833c1b437afc661a7ae368213919e 378 SUPERFAMILY SSF57938 130 210 3.53E-18 T 29-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 SMALA_RS12950 974833c1b437afc661a7ae368213919e 378 Pfam PF00684 DnaJ central domain 143 207 1.9E-12 T 29-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 SMALA_RS12950 974833c1b437afc661a7ae368213919e 378 SUPERFAMILY SSF46565 3 99 1.24E-32 T 29-03-2018 IPR001623 DnaJ domain SMALA_RS12950 974833c1b437afc661a7ae368213919e 378 SUPERFAMILY SSF49493 258 344 2.09E-20 T 29-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 SMALA_RS12950 974833c1b437afc661a7ae368213919e 378 Pfam PF01556 DnaJ C terminal domain 118 333 2.6E-38 T 29-03-2018 IPR002939 Chaperone DnaJ, C-terminal SMALA_RS12950 974833c1b437afc661a7ae368213919e 378 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 1 374 37.745 T 29-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 SMALA_RS12950 974833c1b437afc661a7ae368213919e 378 Gene3D G3DSA:2.60.260.20 255 364 5.3E-27 T 29-03-2018 SMALA_RS11570 922bf2a2dbf070d2499289cad645652e 302 SUPERFAMILY SSF50129 1 137 2.13E-22 T 29-03-2018 IPR011032 GroES-like SMALA_RS11570 922bf2a2dbf070d2499289cad645652e 302 Gene3D G3DSA:3.90.180.10 1 140 4.4E-33 T 29-03-2018 SMALA_RS11570 922bf2a2dbf070d2499289cad645652e 302 SUPERFAMILY SSF51735 106 270 2.35E-30 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS11570 922bf2a2dbf070d2499289cad645652e 302 SMART SM00829 9 299 4.9E-11 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS11570 922bf2a2dbf070d2499289cad645652e 302 Gene3D G3DSA:3.90.180.10 224 302 0.035 T 29-03-2018 SMALA_RS11570 922bf2a2dbf070d2499289cad645652e 302 Pfam PF00107 Zinc-binding dehydrogenase 143 234 2.1E-18 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMALA_RS11570 922bf2a2dbf070d2499289cad645652e 302 Gene3D G3DSA:3.40.50.720 141 223 9.9E-21 T 29-03-2018 SMALA_RS23025 2ba20b56b43b5d8398fb4f916137a732 385 SUPERFAMILY SSF56645 1 37 1.83E-13 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMALA_RS23025 2ba20b56b43b5d8398fb4f916137a732 385 SUPERFAMILY SSF56645 82 147 1.83E-13 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMALA_RS23025 2ba20b56b43b5d8398fb4f916137a732 385 SUPERFAMILY SSF47203 246 358 5.8E-30 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMALA_RS23025 2ba20b56b43b5d8398fb4f916137a732 385 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 248 356 3.2E-23 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMALA_RS23025 2ba20b56b43b5d8398fb4f916137a732 385 Gene3D G3DSA:1.20.140.10 241 362 1.6E-30 T 29-03-2018 SMALA_RS23025 2ba20b56b43b5d8398fb4f916137a732 385 Gene3D G3DSA:1.10.540.10 1 171 1.7E-17 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS23025 2ba20b56b43b5d8398fb4f916137a732 385 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 81 149 3.5E-9 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS07770 db5d1e3466ecc36701b7b17418a4d8fc 240 Pfam PF13419 Haloacid dehalogenase-like hydrolase 20 197 1.3E-10 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS07770 db5d1e3466ecc36701b7b17418a4d8fc 240 SUPERFAMILY SSF56784 17 221 6.76E-31 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS07770 db5d1e3466ecc36701b7b17418a4d8fc 240 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 99 197 9.3E-9 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMALA_RS07770 db5d1e3466ecc36701b7b17418a4d8fc 240 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 15 26 8.3E-10 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMALA_RS07770 db5d1e3466ecc36701b7b17418a4d8fc 240 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 141 157 8.3E-10 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMALA_RS07770 db5d1e3466ecc36701b7b17418a4d8fc 240 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 159 179 8.3E-10 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMALA_RS07770 db5d1e3466ecc36701b7b17418a4d8fc 240 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 111 124 8.3E-10 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMALA_RS07770 db5d1e3466ecc36701b7b17418a4d8fc 240 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 139 192 6.7E-6 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMALA_RS07770 db5d1e3466ecc36701b7b17418a4d8fc 240 Gene3D G3DSA:3.40.50.1000 15 205 3.4E-23 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS23475 e46a4cdbac213a2b3831ca073bf2bb27 189 SUPERFAMILY SSF55811 18 153 5.01E-26 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMALA_RS23475 e46a4cdbac213a2b3831ca073bf2bb27 189 Pfam PF00293 NUDIX domain 44 150 1.2E-17 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SMALA_RS23475 e46a4cdbac213a2b3831ca073bf2bb27 189 ProSitePatterns PS00893 Nudix box signature. 71 92 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 SMALA_RS23475 e46a4cdbac213a2b3831ca073bf2bb27 189 Gene3D G3DSA:3.90.79.10 19 184 1.2E-21 T 29-03-2018 SMALA_RS23475 e46a4cdbac213a2b3831ca073bf2bb27 189 PRINTS PR00502 NUDIX hydrolase family signature 80 95 7.8E-6 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMALA_RS23475 e46a4cdbac213a2b3831ca073bf2bb27 189 PRINTS PR00502 NUDIX hydrolase family signature 66 80 7.8E-6 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMALA_RS33835 1b05a71967eefbb6e9d1351879a752a5 1067 Gene3D G3DSA:2.60.120.260 328 507 1.2E-61 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS33835 1b05a71967eefbb6e9d1351879a752a5 1067 PIRSF PIRSF010631 11 322 1.2E-53 T 29-03-2018 IPR016007 Alpha-L-rhamnosidase SMALA_RS33835 1b05a71967eefbb6e9d1351879a752a5 1067 PIRSF PIRSF010631 327 1064 2.7E-278 T 29-03-2018 IPR016007 Alpha-L-rhamnosidase SMALA_RS33835 1b05a71967eefbb6e9d1351879a752a5 1067 SUPERFAMILY SSF48208 632 1027 3.57E-47 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 SMALA_RS33835 1b05a71967eefbb6e9d1351879a752a5 1067 Gene3D G3DSA:2.60.120.260 149 327 2.6E-30 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS33835 1b05a71967eefbb6e9d1351879a752a5 1067 Gene3D G3DSA:1.50.10.10 628 964 1.2E-54 T 29-03-2018 SMALA_RS33835 1b05a71967eefbb6e9d1351879a752a5 1067 Pfam PF08531 Alpha-L-rhamnosidase N-terminal domain 347 515 2.2E-62 T 29-03-2018 IPR013737 Bacterial alpha-L-rhamnosidase N-terminal SMALA_RS33835 1b05a71967eefbb6e9d1351879a752a5 1067 Gene3D G3DSA:2.60.40.10 35 145 1.1E-26 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS33835 1b05a71967eefbb6e9d1351879a752a5 1067 Pfam PF17389 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain 631 962 6.6E-125 T 29-03-2018 IPR035396 Alpha-L-rhamnosidase, six-hairpin glycosidase domain SMALA_RS33835 1b05a71967eefbb6e9d1351879a752a5 1067 Pfam PF17390 Bacterial alpha-L-rhamnosidase C-terminal domain 964 1035 3.1E-20 T 29-03-2018 IPR035398 Alpha-L-rhamnosidase C-terminal domain SMALA_RS33835 1b05a71967eefbb6e9d1351879a752a5 1067 Gene3D G3DSA:2.60.420.10 965 1064 2.8E-27 T 29-03-2018 SMALA_RS33835 1b05a71967eefbb6e9d1351879a752a5 1067 Gene3D G3DSA:2.60.120.260 508 627 5.5E-44 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS33835 1b05a71967eefbb6e9d1351879a752a5 1067 Pfam PF05592 Bacterial alpha-L-rhamnosidase concanavalin-like domain 527 625 2.3E-32 T 29-03-2018 IPR008902 Alpha-L-rhamnosidase, concanavalin-like domain SMALA_RS33835 1b05a71967eefbb6e9d1351879a752a5 1067 SUPERFAMILY SSF49785 287 412 1.7E-5 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS33835 1b05a71967eefbb6e9d1351879a752a5 1067 SUPERFAMILY SSF49265 60 144 2.07E-5 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 SMALA_RS19325 1f14359640cc9cea09478c4c9241aae0 277 SUPERFAMILY SSF56784 11 272 1.14E-55 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS19325 1f14359640cc9cea09478c4c9241aae0 277 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 14 241 7.8E-25 T 29-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 SMALA_RS19325 1f14359640cc9cea09478c4c9241aae0 277 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 14 268 2.2E-42 T 29-03-2018 IPR000150 Cof family GO:0016787 SMALA_RS19325 1f14359640cc9cea09478c4c9241aae0 277 Gene3D G3DSA:3.40.50.1000 2 277 3.6E-37 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS19325 1f14359640cc9cea09478c4c9241aae0 277 Pfam PF08282 haloacid dehalogenase-like hydrolase 15 268 2.2E-42 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS31270 14744a6c4cf14b31455297dadcab32d0 631 Gene3D G3DSA:2.60.120.200 396 609 1.3E-37 T 29-03-2018 SMALA_RS31270 14744a6c4cf14b31455297dadcab32d0 631 SMART SM00282 458 593 1.1E-6 T 29-03-2018 IPR001791 Laminin G domain SMALA_RS31270 14744a6c4cf14b31455297dadcab32d0 631 Pfam PF13088 BNR repeat-like domain 61 349 1.5E-29 T 29-03-2018 IPR011040 Sialidases KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 SMALA_RS31270 14744a6c4cf14b31455297dadcab32d0 631 Gene3D G3DSA:2.120.10.10 27 395 5.6E-80 T 29-03-2018 SMALA_RS31270 14744a6c4cf14b31455297dadcab32d0 631 SMART SM00560 458 598 8.1E-17 T 29-03-2018 IPR006558 LamG-like jellyroll fold SMALA_RS31270 14744a6c4cf14b31455297dadcab32d0 631 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 439 600 4.2E-21 T 29-03-2018 SMALA_RS31270 14744a6c4cf14b31455297dadcab32d0 631 SUPERFAMILY SSF49899 408 602 1.77E-32 T 29-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain SMALA_RS31270 14744a6c4cf14b31455297dadcab32d0 631 SUPERFAMILY SSF50939 36 398 7.57E-87 T 29-03-2018 IPR011040 Sialidases KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 SMALA_RS16665 c90ce4bfb2af23ca0baf06c19aad7161 226 Gene3D G3DSA:1.10.1740.10 2 125 3.1E-24 T 29-03-2018 SMALA_RS16665 c90ce4bfb2af23ca0baf06c19aad7161 226 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 22 177 5.0E-18 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS16665 c90ce4bfb2af23ca0baf06c19aad7161 226 SUPERFAMILY SSF88946 3 105 2.22E-25 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS16665 c90ce4bfb2af23ca0baf06c19aad7161 226 Pfam PF04542 Sigma-70 region 2 27 93 6.4E-17 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS16665 c90ce4bfb2af23ca0baf06c19aad7161 226 Gene3D G3DSA:1.10.10.10 128 220 2.8E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS16665 c90ce4bfb2af23ca0baf06c19aad7161 226 Pfam PF08281 Sigma-70, region 4 129 176 1.3E-10 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS16665 c90ce4bfb2af23ca0baf06c19aad7161 226 SUPERFAMILY SSF88659 127 180 3.92E-9 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS00640 f09dd3c318d0e54b358df8ca73841c77 268 Pfam PF04545 Sigma-70, region 4 212 259 1.6E-16 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS00640 f09dd3c318d0e54b358df8ca73841c77 268 SUPERFAMILY SSF88659 118 194 1.53E-10 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS00640 f09dd3c318d0e54b358df8ca73841c77 268 Pfam PF04539 Sigma-70 region 3 124 179 4.5E-6 T 29-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS00640 f09dd3c318d0e54b358df8ca73841c77 268 SUPERFAMILY SSF88946 35 114 2.49E-23 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS00640 f09dd3c318d0e54b358df8ca73841c77 268 Gene3D G3DSA:1.10.10.10 116 168 8.6E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS00640 f09dd3c318d0e54b358df8ca73841c77 268 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 42 261 1.4E-29 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS00640 f09dd3c318d0e54b358df8ca73841c77 268 Pfam PF04542 Sigma-70 region 2 46 114 3.2E-15 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS00640 f09dd3c318d0e54b358df8ca73841c77 268 Gene3D G3DSA:1.10.1740.10 34 112 4.8E-17 T 29-03-2018 SMALA_RS00640 f09dd3c318d0e54b358df8ca73841c77 268 PRINTS PR00046 Major sigma-70 factor signature 216 228 3.7E-6 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS00640 f09dd3c318d0e54b358df8ca73841c77 268 PRINTS PR00046 Major sigma-70 factor signature 233 248 3.7E-6 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS00640 f09dd3c318d0e54b358df8ca73841c77 268 PRINTS PR00046 Major sigma-70 factor signature 69 82 3.7E-6 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS00640 f09dd3c318d0e54b358df8ca73841c77 268 SUPERFAMILY SSF88659 184 263 1.55E-15 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS00640 f09dd3c318d0e54b358df8ca73841c77 268 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 39 262 2.6E-84 T 29-03-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS00640 f09dd3c318d0e54b358df8ca73841c77 268 Gene3D G3DSA:1.10.10.10 190 268 7.5E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS38180 b2742cd6b92378c71ba2119a79800944 244 Gene3D G3DSA:1.10.10.10 159 237 3.8E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS38180 b2742cd6b92378c71ba2119a79800944 244 SUPERFAMILY SSF56024 27 157 9.1E-8 T 29-03-2018 SMALA_RS38180 b2742cd6b92378c71ba2119a79800944 244 Gene3D G3DSA:3.30.870.10 4 158 6.0E-5 T 29-03-2018 SMALA_RS38180 b2742cd6b92378c71ba2119a79800944 244 SUPERFAMILY SSF46894 175 231 1.02E-7 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS38180 b2742cd6b92378c71ba2119a79800944 244 Pfam PF11495 Archaeal transcriptional regulator TrmB 29 178 3.4E-6 T 29-03-2018 IPR021586 Transcription regulator TrmB, C-terminal SMALA_RS32995 17224c47dd917669b6339b206445e4a0 462 SUPERFAMILY SSF52540 20 245 9.98E-39 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS32995 17224c47dd917669b6339b206445e4a0 462 Pfam PF16193 AAA C-terminal domain 200 276 7.7E-26 T 29-03-2018 IPR032423 AAA C-terminal domain SMALA_RS32995 17224c47dd917669b6339b206445e4a0 462 Gene3D G3DSA:1.20.272.10 261 355 3.0E-38 T 29-03-2018 SMALA_RS32995 17224c47dd917669b6339b206445e4a0 462 Gene3D G3DSA:1.10.8.60 167 255 1.7E-17 T 29-03-2018 SMALA_RS32995 17224c47dd917669b6339b206445e4a0 462 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 65 169 1.4E-13 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 SMALA_RS32995 17224c47dd917669b6339b206445e4a0 462 Gene3D G3DSA:1.10.3710.10 358 450 3.9E-29 T 29-03-2018 SMALA_RS32995 17224c47dd917669b6339b206445e4a0 462 Gene3D G3DSA:3.40.50.300 8 166 2.6E-23 T 29-03-2018 SMALA_RS32995 17224c47dd917669b6339b206445e4a0 462 SMART SM00382 61 182 2.5E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS32995 17224c47dd917669b6339b206445e4a0 462 Pfam PF12002 MgsA AAA+ ATPase C terminal 277 442 3.9E-68 T 29-03-2018 IPR021886 MgsA AAA+ ATPase C-terminal SMALA_RS32995 17224c47dd917669b6339b206445e4a0 462 SUPERFAMILY SSF48019 262 444 1.02E-72 T 29-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 SMALA_RS23590 9a1d0268f1206285f144b2a1f082f4c7 435 Gene3D G3DSA:3.50.50.60 3 203 1.8E-13 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS23590 9a1d0268f1206285f144b2a1f082f4c7 435 Gene3D G3DSA:3.50.50.60 204 415 3.9E-6 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS23590 9a1d0268f1206285f144b2a1f082f4c7 435 SUPERFAMILY SSF51905 4 258 8.22E-19 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS23590 9a1d0268f1206285f144b2a1f082f4c7 435 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 5 343 3.8E-124 T 29-03-2018 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase SMALA_RS14980 41f35b2235acd596776de3353218d595 100 SUPERFAMILY SSF50129 2 85 1.1E-16 T 29-03-2018 IPR011032 GroES-like SMALA_RS14980 41f35b2235acd596776de3353218d595 100 SMART SM00883 1 85 1.5E-20 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 SMALA_RS14980 41f35b2235acd596776de3353218d595 100 Gene3D G3DSA:2.30.33.40 1 86 3.0E-19 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 SMALA_RS14980 41f35b2235acd596776de3353218d595 100 Pfam PF00166 Chaperonin 10 Kd subunit 1 84 4.2E-18 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 SMALA_RS33140 290a1515c4362be5402eed97ad50ac13 402 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 276 284 - T 29-03-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 SMALA_RS33140 290a1515c4362be5402eed97ad50ac13 402 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 126 136 - T 29-03-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 SMALA_RS33140 290a1515c4362be5402eed97ad50ac13 402 Pfam PF02772 S-adenosylmethionine synthetase, central domain 124 248 1.5E-44 T 29-03-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 SMALA_RS33140 290a1515c4362be5402eed97ad50ac13 402 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 2 400 57.036 T 29-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 SMALA_RS33140 290a1515c4362be5402eed97ad50ac13 402 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 4 101 1.3E-39 T 29-03-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 SMALA_RS33140 290a1515c4362be5402eed97ad50ac13 402 SUPERFAMILY SSF55973 3 109 4.71E-44 T 29-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 SMALA_RS33140 290a1515c4362be5402eed97ad50ac13 402 PIRSF PIRSF000497 1 401 1.4E-163 T 29-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 SMALA_RS33140 290a1515c4362be5402eed97ad50ac13 402 Gene3D G3DSA:3.30.300.10 11 135 4.0E-43 T 29-03-2018 SMALA_RS33140 290a1515c4362be5402eed97ad50ac13 402 Gene3D G3DSA:3.30.300.10 265 402 4.8E-49 T 29-03-2018 SMALA_RS33140 290a1515c4362be5402eed97ad50ac13 402 SUPERFAMILY SSF55973 120 248 1.92E-45 T 29-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 SMALA_RS33140 290a1515c4362be5402eed97ad50ac13 402 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 250 389 6.7E-68 T 29-03-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 SMALA_RS33140 290a1515c4362be5402eed97ad50ac13 402 SUPERFAMILY SSF55973 250 400 3.26E-67 T 29-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 SMALA_RS33140 290a1515c4362be5402eed97ad50ac13 402 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 5 399 4.4E-170 T 29-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 SMALA_RS33140 290a1515c4362be5402eed97ad50ac13 402 Gene3D G3DSA:3.30.300.10 136 249 9.5E-40 T 29-03-2018 SMALA_RS26060 7eca9884b39b6e40669743a767c4c38f 594 Pfam PF01987 Mitochondrial biogenesis AIM24 401 590 3.0E-23 T 29-03-2018 IPR002838 Mitochondrial biogenesis protein AIM24 SMALA_RS26060 7eca9884b39b6e40669743a767c4c38f 594 SUPERFAMILY SSF51219 396 593 2.88E-33 T 29-03-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain SMALA_RS26060 7eca9884b39b6e40669743a767c4c38f 594 Pfam PF02342 TerD domain 1 170 1.4E-34 T 29-03-2018 IPR003325 TerD domain GO:0006950 SMALA_RS26060 7eca9884b39b6e40669743a767c4c38f 594 Gene3D G3DSA:2.60.60.30 20 169 6.5E-31 T 29-03-2018 SMALA_RS26060 7eca9884b39b6e40669743a767c4c38f 594 Gene3D G3DSA:3.60.160.10 386 594 1.0E-39 T 29-03-2018 IPR002838 Mitochondrial biogenesis protein AIM24 SMALA_RS26060 7eca9884b39b6e40669743a767c4c38f 594 PRINTS PR01217 Proline rich extensin signature 201 213 1.2E-13 T 29-03-2018 SMALA_RS26060 7eca9884b39b6e40669743a767c4c38f 594 PRINTS PR01217 Proline rich extensin signature 217 238 1.2E-13 T 29-03-2018 SMALA_RS26060 7eca9884b39b6e40669743a767c4c38f 594 PRINTS PR01217 Proline rich extensin signature 288 313 1.2E-13 T 29-03-2018 SMALA_RS26060 7eca9884b39b6e40669743a767c4c38f 594 PRINTS PR01217 Proline rich extensin signature 263 280 1.2E-13 T 29-03-2018 SMALA_RS26060 7eca9884b39b6e40669743a767c4c38f 594 PRINTS PR01217 Proline rich extensin signature 241 257 1.2E-13 T 29-03-2018 SMALA_RS42585 dd982b9de6265c11c661f592eb249496 241 Gene3D G3DSA:3.40.50.1820 1 235 2.3E-30 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS42585 dd982b9de6265c11c661f592eb249496 241 SUPERFAMILY SSF53474 5 237 5.21E-37 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS42585 dd982b9de6265c11c661f592eb249496 241 Pfam PF01738 Dienelactone hydrolase family 20 235 5.8E-27 T 29-03-2018 IPR002925 Dienelactone hydrolase GO:0016787 SMALA_RS13595 03f1f1c79dc889fd8b8cf76d41cc81c0 329 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 58 72 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 SMALA_RS13595 03f1f1c79dc889fd8b8cf76d41cc81c0 329 SUPERFAMILY SSF51735 137 295 2.39E-29 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS13595 03f1f1c79dc889fd8b8cf76d41cc81c0 329 Gene3D G3DSA:3.90.180.10 1 158 7.6E-54 T 29-03-2018 SMALA_RS13595 03f1f1c79dc889fd8b8cf76d41cc81c0 329 Gene3D G3DSA:3.40.50.720 159 297 1.6E-12 T 29-03-2018 SMALA_RS13595 03f1f1c79dc889fd8b8cf76d41cc81c0 329 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 131 1.8E-31 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS13595 03f1f1c79dc889fd8b8cf76d41cc81c0 329 TIGRFAM TIGR02822 adh_fam_2: zinc-binding alcohol dehydrogenase family protein 9 325 4.2E-163 T 29-03-2018 IPR014187 Alcohol dehydrogenase, zinc-binding type 2 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396 SMALA_RS13595 03f1f1c79dc889fd8b8cf76d41cc81c0 329 SUPERFAMILY SSF50129 1 164 1.34E-48 T 29-03-2018 IPR011032 GroES-like SMALA_RS02895 9f3c4fa23a2fea98e582867c1cfaff25 238 SUPERFAMILY SSF51735 3 234 1.21E-60 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS02895 9f3c4fa23a2fea98e582867c1cfaff25 238 Pfam PF00106 short chain dehydrogenase 5 198 5.4E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS02895 9f3c4fa23a2fea98e582867c1cfaff25 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 1.3E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS02895 9f3c4fa23a2fea98e582867c1cfaff25 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 1.3E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS02895 9f3c4fa23a2fea98e582867c1cfaff25 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 120 136 1.3E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS02895 9f3c4fa23a2fea98e582867c1cfaff25 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 199 219 1.3E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS02895 9f3c4fa23a2fea98e582867c1cfaff25 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 1.3E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS02895 9f3c4fa23a2fea98e582867c1cfaff25 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 1.3E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS02895 9f3c4fa23a2fea98e582867c1cfaff25 238 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 6.9E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS02895 9f3c4fa23a2fea98e582867c1cfaff25 238 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 126 134 6.9E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS02895 9f3c4fa23a2fea98e582867c1cfaff25 238 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 72 83 6.9E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS02895 9f3c4fa23a2fea98e582867c1cfaff25 238 Gene3D G3DSA:3.40.50.720 1 238 3.0E-61 T 29-03-2018 SMALA_RS36145 bdbd5e66a5cb96e17069736747df16de 385 Gene3D G3DSA:3.40.47.10 264 382 2.0E-32 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS36145 bdbd5e66a5cb96e17069736747df16de 385 SUPERFAMILY SSF53901 3 262 3.42E-70 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS36145 bdbd5e66a5cb96e17069736747df16de 385 SUPERFAMILY SSF53901 263 384 3.63E-42 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS36145 bdbd5e66a5cb96e17069736747df16de 385 ProSitePatterns PS00737 Thiolases signature 2. 331 347 - T 29-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 SMALA_RS36145 bdbd5e66a5cb96e17069736747df16de 385 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 383 1.0E-126 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 SMALA_RS36145 bdbd5e66a5cb96e17069736747df16de 385 Pfam PF00108 Thiolase, N-terminal domain 5 255 6.8E-56 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 SMALA_RS36145 bdbd5e66a5cb96e17069736747df16de 385 Gene3D G3DSA:3.40.47.10 1 153 5.0E-32 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS36145 bdbd5e66a5cb96e17069736747df16de 385 Gene3D G3DSA:3.40.47.10 154 263 8.0E-17 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS36145 bdbd5e66a5cb96e17069736747df16de 385 Pfam PF02803 Thiolase, C-terminal domain 263 384 3.0E-44 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 SMALA_RS36145 bdbd5e66a5cb96e17069736747df16de 385 PIRSF PIRSF000429 1 385 2.8E-122 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 SMALA_RS00055 233958865474854d6e3ef4e43ad4bc67 166 Pfam PF12728 Helix-turn-helix domain 6 51 2.3E-7 T 29-03-2018 SMALA_RS00055 233958865474854d6e3ef4e43ad4bc67 166 Gene3D G3DSA:1.10.260.40 1 115 5.8E-7 T 29-03-2018 SMALA_RS00055 233958865474854d6e3ef4e43ad4bc67 166 SUPERFAMILY SSF46955 6 50 1.67E-5 T 29-03-2018 IPR009061 Putative DNA-binding domain SMALA_RS24010 64d21512922f8801bb1d8791dc22a9bc 165 ProSitePatterns PS01117 MarR-type HTH domain signature. 85 119 - T 29-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site SMALA_RS24010 64d21512922f8801bb1d8791dc22a9bc 165 SMART SM00347 43 146 1.3E-23 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS24010 64d21512922f8801bb1d8791dc22a9bc 165 Gene3D G3DSA:1.10.10.10 1 162 4.1E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS24010 64d21512922f8801bb1d8791dc22a9bc 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 136 156 4.0E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS24010 64d21512922f8801bb1d8791dc22a9bc 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 86 4.0E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS24010 64d21512922f8801bb1d8791dc22a9bc 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 106 122 4.0E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS24010 64d21512922f8801bb1d8791dc22a9bc 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 102 4.0E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS24010 64d21512922f8801bb1d8791dc22a9bc 165 Pfam PF01047 MarR family 54 111 2.3E-12 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS24010 64d21512922f8801bb1d8791dc22a9bc 165 SUPERFAMILY SSF46785 11 160 1.43E-34 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS19240 690d544d1d0b2506ee56b8b6643bb9e8 277 SUPERFAMILY SSF51695 18 272 1.78E-65 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 SMALA_RS19240 690d544d1d0b2506ee56b8b6643bb9e8 277 Gene3D G3DSA:3.20.20.190 15 275 2.5E-75 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 SMALA_RS19240 690d544d1d0b2506ee56b8b6643bb9e8 277 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 22 268 6.5E-45 T 29-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 SMALA_RS08605 b12b32202e9cee2f332c1f298efe5930 121 Pfam PF00741 Gas vesicle protein 22 60 1.2E-16 T 29-03-2018 IPR000638 Gas vesicle protein GvpA GO:0005198|GO:0012506 SMALA_RS08605 b12b32202e9cee2f332c1f298efe5930 121 ProSitePatterns PS00234 Gas vesicles protein GVPa signature 1. 23 37 - T 29-03-2018 IPR018493 Gas vesicle protein GvpA, conserved site GO:0005198|GO:0012506 SMALA_RS10150 fa4819266823f492a056fb81b0040227 378 Gene3D G3DSA:3.30.70.100 252 329 0.0018 T 29-03-2018 SMALA_RS10150 fa4819266823f492a056fb81b0040227 378 SUPERFAMILY SSF50182 179 244 4.25E-16 T 29-03-2018 IPR010920 LSM domain SMALA_RS10150 fa4819266823f492a056fb81b0040227 378 Pfam PF00924 Mechanosensitive ion channel 142 328 5.2E-35 T 29-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 SMALA_RS10150 fa4819266823f492a056fb81b0040227 378 Gene3D G3DSA:2.30.30.60 195 245 2.8E-14 T 29-03-2018 SMALA_RS11390 b0459282f6d477461f6e4faa3bb4d9d1 224 SUPERFAMILY SSF53335 47 202 2.16E-16 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS11390 b0459282f6d477461f6e4faa3bb4d9d1 224 Pfam PF13578 Methyltransferase domain 51 179 7.3E-24 T 29-03-2018 SMALA_RS11390 b0459282f6d477461f6e4faa3bb4d9d1 224 Gene3D G3DSA:3.40.50.150 19 211 9.4E-22 T 29-03-2018 SMALA_RS14990 abf58941156f95aa002b4f1f6dea47cb 155 SUPERFAMILY SSF52833 4 153 6.26E-45 T 29-03-2018 IPR012336 Thioredoxin-like fold SMALA_RS14990 abf58941156f95aa002b4f1f6dea47cb 155 Pfam PF00578 AhpC/TSA family 8 134 3.4E-34 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 SMALA_RS14990 abf58941156f95aa002b4f1f6dea47cb 155 Gene3D G3DSA:3.40.30.10 1 153 5.1E-38 T 29-03-2018 SMALA_RS33870 b98775e860ac1352498be79cf9ef332f 341 Gene3D G3DSA:3.40.50.2300 179 321 1.7E-41 T 29-03-2018 SMALA_RS33870 b98775e860ac1352498be79cf9ef332f 341 Pfam PF00356 Bacterial regulatory proteins, lacI family 7 50 2.9E-17 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS33870 b98775e860ac1352498be79cf9ef332f 341 SMART SM00354 4 74 3.7E-25 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS33870 b98775e860ac1352498be79cf9ef332f 341 SUPERFAMILY SSF53822 64 335 2.36E-70 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SMALA_RS33870 b98775e860ac1352498be79cf9ef332f 341 Gene3D G3DSA:1.10.260.40 5 58 1.1E-20 T 29-03-2018 SMALA_RS33870 b98775e860ac1352498be79cf9ef332f 341 SUPERFAMILY SSF47413 5 62 1.03E-15 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS33870 b98775e860ac1352498be79cf9ef332f 341 Gene3D G3DSA:3.40.50.2300 59 178 2.3E-37 T 29-03-2018 SMALA_RS33870 b98775e860ac1352498be79cf9ef332f 341 Pfam PF13377 Periplasmic binding protein-like domain 171 335 4.1E-34 T 29-03-2018 SMALA_RS33870 b98775e860ac1352498be79cf9ef332f 341 ProSitePatterns PS00356 LacI-type HTH domain signature. 7 25 - T 29-03-2018 SMALA_RS06795 a31e697db53c8cb30ecc799401c60128 138 SUPERFAMILY SSF50118 86 134 3.2E-6 T 29-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor SMALA_RS06795 a31e697db53c8cb30ecc799401c60128 138 SUPERFAMILY SSF50118 2 43 3.2E-6 T 29-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor SMALA_RS20010 fbe521711b2a37aabe0e5d8afa702539 189 Pfam PF10759 Protein of unknown function (DUF2587) 37 188 2.4E-78 T 29-03-2018 IPR019695 Bacterial proteasome activator GO:0061136 SMALA_RS24380 49b195cbb146ce92f5f6c3d5dc8b2954 472 SUPERFAMILY SSF53686 72 380 6.42E-95 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMALA_RS24380 49b195cbb146ce92f5f6c3d5dc8b2954 472 Gene3D G3DSA:3.30.70.260 393 470 3.1E-8 T 29-03-2018 SMALA_RS24380 49b195cbb146ce92f5f6c3d5dc8b2954 472 Gene3D G3DSA:3.40.50.1100 200 391 2.7E-49 T 29-03-2018 SMALA_RS24380 49b195cbb146ce92f5f6c3d5dc8b2954 472 SUPERFAMILY SSF55021 390 467 9.87E-6 T 29-03-2018 SMALA_RS24380 49b195cbb146ce92f5f6c3d5dc8b2954 472 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 88 371 4.0E-85 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMALA_RS24380 49b195cbb146ce92f5f6c3d5dc8b2954 472 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 111 124 - T 29-03-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 SMALA_RS24380 49b195cbb146ce92f5f6c3d5dc8b2954 472 Gene3D G3DSA:3.40.50.1100 100 199 7.6E-31 T 29-03-2018 SMALA_RS24380 49b195cbb146ce92f5f6c3d5dc8b2954 472 TIGRFAM TIGR01127 ilvA_1Cterm: threonine ammonia-lyase 90 467 1.6E-133 T 29-03-2018 IPR005789 Threonine dehydratase, catabolic GO:0004794|GO:0006567 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 SMALA_RS17045 3f957473042a86f90597e2cb333e3e11 596 SUPERFAMILY SSF51905 486 546 6.48E-48 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS17045 3f957473042a86f90597e2cb333e3e11 596 SUPERFAMILY SSF51905 8 165 6.48E-48 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS17045 3f957473042a86f90597e2cb333e3e11 596 SUPERFAMILY SSF51905 201 312 6.48E-48 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS17045 3f957473042a86f90597e2cb333e3e11 596 Pfam PF00890 FAD binding domain 12 45 8.9E-6 T 29-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMALA_RS17045 3f957473042a86f90597e2cb333e3e11 596 Pfam PF05199 GMC oxidoreductase 484 541 4.7E-14 T 29-03-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 SMALA_RS17045 3f957473042a86f90597e2cb333e3e11 596 Gene3D G3DSA:3.50.50.60 2 563 1.9E-58 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS42420 800257b95f027d36496f399058116061 265 Gene3D G3DSA:3.60.10.10 31 263 1.1E-26 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMALA_RS42420 800257b95f027d36496f399058116061 265 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 48 255 3.9E-12 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMALA_RS42420 800257b95f027d36496f399058116061 265 SUPERFAMILY SSF56219 44 263 7.98E-30 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMALA_RS00280 207d5588644f7ae02fc0771bb3a826b7 463 SUPERFAMILY SSF75304 1 460 7.19E-141 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMALA_RS00280 207d5588644f7ae02fc0771bb3a826b7 463 Pfam PF01425 Amidase 24 444 1.4E-123 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMALA_RS00280 207d5588644f7ae02fc0771bb3a826b7 463 Gene3D G3DSA:3.90.1300.10 2 463 1.3E-149 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMALA_RS00280 207d5588644f7ae02fc0771bb3a826b7 463 ProSitePatterns PS00571 Amidases signature. 147 178 - T 29-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 SMALA_RS32580 cb9012753178b11a862d5b1641e64f56 417 Gene3D G3DSA:3.30.950.10 111 201 3.7E-26 T 29-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMALA_RS32580 cb9012753178b11a862d5b1641e64f56 417 Gene3D G3DSA:3.40.50.150 253 408 2.0E-14 T 29-03-2018 SMALA_RS32580 cb9012753178b11a862d5b1641e64f56 417 TIGRFAM TIGR02467 CbiE: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit 11 196 8.4E-37 T 29-03-2018 IPR012818 Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase GO:0008276|GO:0009236 SMALA_RS32580 cb9012753178b11a862d5b1641e64f56 417 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 15 182 6.8E-20 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMALA_RS32580 cb9012753178b11a862d5b1641e64f56 417 SUPERFAMILY SSF53335 256 387 1.73E-14 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS32580 cb9012753178b11a862d5b1641e64f56 417 SUPERFAMILY SSF53790 8 197 4.32E-32 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMALA_RS32580 cb9012753178b11a862d5b1641e64f56 417 Gene3D G3DSA:3.40.1010.10 4 110 7.3E-10 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMALA_RS32580 cb9012753178b11a862d5b1641e64f56 417 PIRSF PIRSF036428 1 415 2.9E-79 T 29-03-2018 IPR006365 Cobalamin (vitamin B12) biosynthesis CobL/Precorrin-6Y C(5,15)-methyltransferase GO:0008276|GO:0009236 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|KEGG: 00860+2.1.1.132|MetaCyc: PWY-2201|MetaCyc: PWY-3841 SMALA_RS13345 11d298b007086bb0072bb536c4a89f42 211 Gene3D G3DSA:3.40.30.10 5 61 1.1E-10 T 29-03-2018 SMALA_RS13345 11d298b007086bb0072bb536c4a89f42 211 Pfam PF01323 DSBA-like thioredoxin domain 10 168 5.4E-8 T 29-03-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 SMALA_RS13345 11d298b007086bb0072bb536c4a89f42 211 SUPERFAMILY SSF52833 10 171 1.34E-22 T 29-03-2018 IPR012336 Thioredoxin-like fold SMALA_RS13345 11d298b007086bb0072bb536c4a89f42 211 Gene3D G3DSA:3.40.30.10 62 172 6.5E-12 T 29-03-2018 SMALA_RS03960 9e30b6d35781adb414691bf070595b7c 221 SMART SM00421 152 209 1.6E-23 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS03960 9e30b6d35781adb414691bf070595b7c 221 Gene3D G3DSA:1.10.10.10 136 214 1.2E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS03960 9e30b6d35781adb414691bf070595b7c 221 Gene3D G3DSA:3.40.50.2300 1 135 1.2E-38 T 29-03-2018 SMALA_RS03960 9e30b6d35781adb414691bf070595b7c 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 5.8E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS03960 9e30b6d35781adb414691bf070595b7c 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 5.8E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS03960 9e30b6d35781adb414691bf070595b7c 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 5.8E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS03960 9e30b6d35781adb414691bf070595b7c 221 SUPERFAMILY SSF52172 2 128 1.25E-32 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS03960 9e30b6d35781adb414691bf070595b7c 221 SUPERFAMILY SSF46894 145 215 1.87E-21 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS03960 9e30b6d35781adb414691bf070595b7c 221 SMART SM00448 2 117 4.0E-31 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS03960 9e30b6d35781adb414691bf070595b7c 221 Pfam PF00072 Response regulator receiver domain 4 117 5.6E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS03960 9e30b6d35781adb414691bf070595b7c 221 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 209 2.3E-16 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS02915 13a3e7cf0291f639257e6bf613c3fbcb 220 Gene3D G3DSA:1.10.10.60 23 86 2.8E-18 T 29-03-2018 SMALA_RS02915 13a3e7cf0291f639257e6bf613c3fbcb 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 61 84 7.2E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS02915 13a3e7cf0291f639257e6bf613c3fbcb 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 53 7.2E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS02915 13a3e7cf0291f639257e6bf613c3fbcb 220 Gene3D G3DSA:1.10.357.10 87 212 3.9E-16 T 29-03-2018 SMALA_RS02915 13a3e7cf0291f639257e6bf613c3fbcb 220 Pfam PF00440 Bacterial regulatory proteins, tetR family 41 86 1.9E-15 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS02915 13a3e7cf0291f639257e6bf613c3fbcb 220 SUPERFAMILY SSF48498 103 209 1.04E-15 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS02915 13a3e7cf0291f639257e6bf613c3fbcb 220 SUPERFAMILY SSF46689 26 87 3.09E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS38295 37671f7c5578da6fd1d603b461673271 272 SUPERFAMILY SSF52540 12 245 3.46E-81 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS38295 37671f7c5578da6fd1d603b461673271 272 SMART SM00382 36 223 2.2E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS38295 37671f7c5578da6fd1d603b461673271 272 Pfam PF00005 ABC transporter 27 175 5.7E-36 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS38295 37671f7c5578da6fd1d603b461673271 272 PIRSF PIRSF039085 8 251 3.2E-114 T 29-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 SMALA_RS38295 37671f7c5578da6fd1d603b461673271 272 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS38295 37671f7c5578da6fd1d603b461673271 272 Gene3D G3DSA:3.40.50.300 10 264 2.0E-80 T 29-03-2018 SMALA_RS40970 122a33730339f7b8320ec165326d6b16 392 SUPERFAMILY SSF53901 222 379 1.81E-14 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS40970 122a33730339f7b8320ec165326d6b16 392 SUPERFAMILY SSF53901 21 250 6.01E-35 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS40970 122a33730339f7b8320ec165326d6b16 392 Gene3D G3DSA:3.40.47.10 21 258 7.1E-37 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS40970 122a33730339f7b8320ec165326d6b16 392 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 273 350 4.4E-6 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS40970 122a33730339f7b8320ec165326d6b16 392 Gene3D G3DSA:3.40.47.10 264 356 1.8E-7 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS40970 122a33730339f7b8320ec165326d6b16 392 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 21 217 5.5E-18 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS08755 3f8b7ba9a7bcf54df09286540b278a15 290 Pfam PF01479 S4 domain 8 51 2.1E-10 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SMALA_RS08755 3f8b7ba9a7bcf54df09286540b278a15 290 SUPERFAMILY SSF55174 7 84 4.97E-15 T 29-03-2018 SMALA_RS08755 3f8b7ba9a7bcf54df09286540b278a15 290 Pfam PF01728 FtsJ-like methyltransferase 65 268 5.7E-16 T 29-03-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 SMALA_RS08755 3f8b7ba9a7bcf54df09286540b278a15 290 SMART SM00363 7 74 2.0E-7 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SMALA_RS08755 3f8b7ba9a7bcf54df09286540b278a15 290 Gene3D G3DSA:3.10.290.10 1 67 3.8E-16 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SMALA_RS08755 3f8b7ba9a7bcf54df09286540b278a15 290 Gene3D G3DSA:3.40.50.150 68 287 1.2E-53 T 29-03-2018 SMALA_RS08755 3f8b7ba9a7bcf54df09286540b278a15 290 SUPERFAMILY SSF53335 64 270 4.59E-20 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS08755 3f8b7ba9a7bcf54df09286540b278a15 290 PIRSF PIRSF005578 2 287 1.2E-89 T 29-03-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 SMALA_RS40945 84ccdb1c60d94a89e24e64e34991c00f 335 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 24 319 1.5E-33 T 29-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 SMALA_RS40945 84ccdb1c60d94a89e24e64e34991c00f 335 PIRSF PIRSF001439 2 328 1.4E-65 T 29-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 SMALA_RS40945 84ccdb1c60d94a89e24e64e34991c00f 335 SUPERFAMILY SSF51735 3 326 4.37E-65 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS40945 84ccdb1c60d94a89e24e64e34991c00f 335 TIGRFAM TIGR03944 dehyd_SbnB_fam: 2,3-diaminopropionate biosynthesis protein SbnB 5 328 3.2E-126 T 29-03-2018 IPR023866 2,3-diaminopropionate biosynthesis protein SbnB SMALA_RS40945 84ccdb1c60d94a89e24e64e34991c00f 335 Gene3D G3DSA:3.30.1780.10 1 140 5.4E-35 T 29-03-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 SMALA_RS40945 84ccdb1c60d94a89e24e64e34991c00f 335 Gene3D G3DSA:3.40.50.720 141 300 2.5E-20 T 29-03-2018 SMALA_RS35010 78ddfcc247fea5bdd6e82fce87121aa0 623 SUPERFAMILY SSF90123 21 328 1.15E-52 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMALA_RS35010 78ddfcc247fea5bdd6e82fce87121aa0 623 Pfam PF00005 ABC transporter 374 549 3.0E-21 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS35010 78ddfcc247fea5bdd6e82fce87121aa0 623 SUPERFAMILY SSF52540 490 615 1.62E-51 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS35010 78ddfcc247fea5bdd6e82fce87121aa0 623 SUPERFAMILY SSF52540 356 449 1.62E-51 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS35010 78ddfcc247fea5bdd6e82fce87121aa0 623 Pfam PF00664 ABC transporter transmembrane region 32 299 3.2E-28 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMALA_RS35010 78ddfcc247fea5bdd6e82fce87121aa0 623 SMART SM00382 383 595 1.0E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS35010 78ddfcc247fea5bdd6e82fce87121aa0 623 Gene3D G3DSA:1.20.1560.10 11 329 7.9E-46 T 29-03-2018 SMALA_RS35010 78ddfcc247fea5bdd6e82fce87121aa0 623 Gene3D G3DSA:3.40.50.300 355 618 1.1E-56 T 29-03-2018 SMALA_RS08040 b1db4bb87ab102cfc8ab3151bbe99925 397 SUPERFAMILY SSF53756 1 370 1.26E-65 T 29-03-2018 SMALA_RS08040 b1db4bb87ab102cfc8ab3151bbe99925 397 Gene3D G3DSA:3.40.50.2000 1 182 4.9E-21 T 29-03-2018 SMALA_RS08040 b1db4bb87ab102cfc8ab3151bbe99925 397 Pfam PF13692 Glycosyl transferases group 1 196 336 6.5E-17 T 29-03-2018 SMALA_RS08040 b1db4bb87ab102cfc8ab3151bbe99925 397 Pfam PF13439 Glycosyltransferase Family 4 12 171 5.9E-24 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 SMALA_RS08040 b1db4bb87ab102cfc8ab3151bbe99925 397 Gene3D G3DSA:3.40.50.2000 183 375 6.6E-33 T 29-03-2018 SMALA_RS36280 245acc71889edc6d6bfcebd16e7f0277 261 Gene3D G3DSA:3.40.50.1360 72 245 1.7E-42 T 29-03-2018 SMALA_RS36280 245acc71889edc6d6bfcebd16e7f0277 261 SUPERFAMILY SSF100950 76 243 1.42E-29 T 29-03-2018 SMALA_RS36280 245acc71889edc6d6bfcebd16e7f0277 261 SUPERFAMILY SSF46785 4 66 1.5E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS36280 245acc71889edc6d6bfcebd16e7f0277 261 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 9.1E-8 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMALA_RS36280 245acc71889edc6d6bfcebd16e7f0277 261 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 9.1E-8 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMALA_RS36280 245acc71889edc6d6bfcebd16e7f0277 261 SMART SM01134 72 242 6.4E-63 T 29-03-2018 SMALA_RS36280 245acc71889edc6d6bfcebd16e7f0277 261 Pfam PF08220 DeoR-like helix-turn-helix domain 6 58 3.9E-16 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMALA_RS36280 245acc71889edc6d6bfcebd16e7f0277 261 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 29-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 SMALA_RS36280 245acc71889edc6d6bfcebd16e7f0277 261 Pfam PF00455 DeoR C terminal sensor domain 75 241 8.8E-49 T 29-03-2018 IPR014036 DeoR C-terminal sensor domain SMALA_RS36280 245acc71889edc6d6bfcebd16e7f0277 261 Gene3D G3DSA:1.10.10.10 1 71 8.4E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS36280 245acc71889edc6d6bfcebd16e7f0277 261 SMART SM00420 6 58 2.5E-14 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMALA_RS09960 e545c89385c38373e42fe03c6778e487 415 Gene3D G3DSA:3.40.50.1100 211 414 6.6E-43 T 29-03-2018 SMALA_RS09960 e545c89385c38373e42fe03c6778e487 415 Gene3D G3DSA:3.40.50.1100 21 76 3.9E-8 T 29-03-2018 SMALA_RS09960 e545c89385c38373e42fe03c6778e487 415 Gene3D G3DSA:3.40.50.1100 77 210 2.7E-40 T 29-03-2018 SMALA_RS09960 e545c89385c38373e42fe03c6778e487 415 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 19 401 5.0E-184 T 29-03-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 SMALA_RS09960 e545c89385c38373e42fe03c6778e487 415 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 14 403 51.642 T 29-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 SMALA_RS09960 e545c89385c38373e42fe03c6778e487 415 PIRSF PIRSF001413 8 408 1.6E-160 T 29-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 SMALA_RS09960 e545c89385c38373e42fe03c6778e487 415 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 93 107 - T 29-03-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 SMALA_RS09960 e545c89385c38373e42fe03c6778e487 415 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 64 390 1.5E-50 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMALA_RS09960 e545c89385c38373e42fe03c6778e487 415 SUPERFAMILY SSF53686 15 402 4.71E-146 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMALA_RS25885 5fabc8b5e567213c9c1bef3099ac3678 284 Gene3D G3DSA:3.20.20.140 1 256 2.8E-47 T 29-03-2018 SMALA_RS25885 5fabc8b5e567213c9c1bef3099ac3678 284 SMART SM00481 3 67 5.4E-13 T 29-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal SMALA_RS25885 5fabc8b5e567213c9c1bef3099ac3678 284 SUPERFAMILY SSF89550 2 80 2.16E-43 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 SMALA_RS25885 5fabc8b5e567213c9c1bef3099ac3678 284 SUPERFAMILY SSF89550 163 256 2.16E-43 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 SMALA_RS25885 5fabc8b5e567213c9c1bef3099ac3678 284 Pfam PF02811 PHP domain 4 70 2.1E-9 T 29-03-2018 IPR004013 PHP domain GO:0003824 SMALA_RS30540 01eff8df6e93f16cee900a13a6323835 202 Pfam PF12804 MobA-like NTP transferase domain 13 175 1.5E-35 T 29-03-2018 IPR025877 MobA-like NTP transferase SMALA_RS30540 01eff8df6e93f16cee900a13a6323835 202 Gene3D G3DSA:3.90.550.10 9 195 1.6E-32 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS30540 01eff8df6e93f16cee900a13a6323835 202 SUPERFAMILY SSF53448 11 198 8.34E-33 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS19335 fd7f572935007b3d6f7337ad1af39a5a 334 Gene3D G3DSA:1.10.10.10 183 237 7.7E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS19335 fd7f572935007b3d6f7337ad1af39a5a 334 SMART SM00344 6 107 0.0016 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 SMALA_RS19335 fd7f572935007b3d6f7337ad1af39a5a 334 SMART SM00344 183 284 7.2E-5 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 SMALA_RS19335 fd7f572935007b3d6f7337ad1af39a5a 334 Gene3D G3DSA:3.30.70.920 238 323 5.6E-16 T 29-03-2018 SMALA_RS19335 fd7f572935007b3d6f7337ad1af39a5a 334 Gene3D G3DSA:3.30.70.920 57 149 9.3E-5 T 29-03-2018 SMALA_RS19335 fd7f572935007b3d6f7337ad1af39a5a 334 Pfam PF13404 AsnC-type helix-turn-helix domain 7 47 7.2E-14 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMALA_RS19335 fd7f572935007b3d6f7337ad1af39a5a 334 Pfam PF13404 AsnC-type helix-turn-helix domain 183 220 2.0E-11 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMALA_RS19335 fd7f572935007b3d6f7337ad1af39a5a 334 SUPERFAMILY SSF46785 6 53 1.69E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS19335 fd7f572935007b3d6f7337ad1af39a5a 334 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 22 33 3.5E-6 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMALA_RS19335 fd7f572935007b3d6f7337ad1af39a5a 334 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 6 22 3.5E-6 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMALA_RS19335 fd7f572935007b3d6f7337ad1af39a5a 334 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 33 52 3.5E-6 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMALA_RS19335 fd7f572935007b3d6f7337ad1af39a5a 334 Gene3D G3DSA:1.10.10.10 1 54 5.9E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS19335 fd7f572935007b3d6f7337ad1af39a5a 334 SUPERFAMILY SSF46785 182 237 6.07E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS19335 fd7f572935007b3d6f7337ad1af39a5a 334 SUPERFAMILY SSF54909 240 317 9.12E-12 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel SMALA_RS19335 fd7f572935007b3d6f7337ad1af39a5a 334 Pfam PF01037 Lrp/AsnC ligand binding domain 244 314 4.4E-13 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain SMALA_RS35665 65592178a14ba4f0f0eb35083594fe98 435 Pfam PF03600 Citrate transporter 13 378 4.5E-47 T 29-03-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 SMALA_RS35665 65592178a14ba4f0f0eb35083594fe98 435 TIGRFAM TIGR00784 citMHS: citrate transporter 1 433 9.1E-153 T 29-03-2018 IPR014738 Citrate transporter GO:0015137|GO:0015746 SMALA_RS32915 5a67a16d197ac5b5a3e68b2ae3df0d50 206 Pfam PF01330 RuvA N terminal domain 1 61 2.1E-18 T 29-03-2018 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 SMALA_RS32915 5a67a16d197ac5b5a3e68b2ae3df0d50 206 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 181 2.8E-37 T 29-03-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 SMALA_RS32915 5a67a16d197ac5b5a3e68b2ae3df0d50 206 SUPERFAMILY SSF46929 149 204 5.23E-8 T 29-03-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 SMALA_RS32915 5a67a16d197ac5b5a3e68b2ae3df0d50 206 Gene3D G3DSA:1.10.150.20 66 134 3.9E-14 T 29-03-2018 SMALA_RS32915 5a67a16d197ac5b5a3e68b2ae3df0d50 206 SUPERFAMILY SSF47781 65 132 1.06E-18 T 29-03-2018 IPR010994 RuvA domain 2-like SMALA_RS32915 5a67a16d197ac5b5a3e68b2ae3df0d50 206 Pfam PF14520 Helix-hairpin-helix domain 71 129 1.2E-15 T 29-03-2018 SMALA_RS32915 5a67a16d197ac5b5a3e68b2ae3df0d50 206 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 203 26.932 T 29-03-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 SMALA_RS32915 5a67a16d197ac5b5a3e68b2ae3df0d50 206 SUPERFAMILY SSF50249 1 62 1.2E-13 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMALA_RS32915 5a67a16d197ac5b5a3e68b2ae3df0d50 206 SMART SM00278 107 126 0.065 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 SMALA_RS32915 5a67a16d197ac5b5a3e68b2ae3df0d50 206 SMART SM00278 72 91 50.0 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 SMALA_RS32915 5a67a16d197ac5b5a3e68b2ae3df0d50 206 Pfam PF07499 RuvA, C-terminal domain 150 202 4.5E-10 T 29-03-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 SMALA_RS32915 5a67a16d197ac5b5a3e68b2ae3df0d50 206 Gene3D G3DSA:2.40.50.140 1 62 2.5E-22 T 29-03-2018 SMALA_RS32915 5a67a16d197ac5b5a3e68b2ae3df0d50 206 Gene3D G3DSA:1.10.8.10 151 206 3.8E-17 T 29-03-2018 SMALA_RS07800 39587e886a9dc5fab54bf4275fdf097f 356 SUPERFAMILY SSF55979 124 237 6.04E-11 T 29-03-2018 SMALA_RS07800 39587e886a9dc5fab54bf4275fdf097f 356 SUPERFAMILY SSF46955 6 92 1.97E-17 T 29-03-2018 IPR009061 Putative DNA-binding domain SMALA_RS07800 39587e886a9dc5fab54bf4275fdf097f 356 Pfam PF02767 DNA polymerase III beta subunit, central domain 121 235 1.3E-8 T 29-03-2018 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMALA_RS07800 39587e886a9dc5fab54bf4275fdf097f 356 Gene3D G3DSA:1.10.1660.10 4 128 4.8E-17 T 29-03-2018 SMALA_RS07800 39587e886a9dc5fab54bf4275fdf097f 356 SMART SM00480 19 348 0.009 T 29-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMALA_RS07800 39587e886a9dc5fab54bf4275fdf097f 356 Gene3D G3DSA:3.10.150.10 129 240 8.8E-25 T 29-03-2018 SMALA_RS07800 39587e886a9dc5fab54bf4275fdf097f 356 SMART SM00422 7 77 1.2E-12 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS07800 39587e886a9dc5fab54bf4275fdf097f 356 Gene3D G3DSA:3.10.150.10 243 354 1.5E-14 T 29-03-2018 SMALA_RS07800 39587e886a9dc5fab54bf4275fdf097f 356 SUPERFAMILY SSF55979 247 351 2.83E-6 T 29-03-2018 SMALA_RS07800 39587e886a9dc5fab54bf4275fdf097f 356 Pfam PF13411 MerR HTH family regulatory protein 7 76 2.7E-13 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS10400 c97614e13b74c0db14f70b0cdc19aad8 673 SUPERFAMILY SSF56322 59 418 1.83E-53 T 29-03-2018 IPR005801 ADC synthase GO:0009058 SMALA_RS10400 c97614e13b74c0db14f70b0cdc19aad8 673 Pfam PF00117 Glutamine amidotransferase class-I 484 665 1.3E-23 T 29-03-2018 IPR017926 Glutamine amidotransferase SMALA_RS10400 c97614e13b74c0db14f70b0cdc19aad8 673 PRINTS PR00097 Anthranilate synthase component II signature 647 660 4.4E-9 T 29-03-2018 SMALA_RS10400 c97614e13b74c0db14f70b0cdc19aad8 673 PRINTS PR00097 Anthranilate synthase component II signature 527 536 4.4E-9 T 29-03-2018 SMALA_RS10400 c97614e13b74c0db14f70b0cdc19aad8 673 PRINTS PR00097 Anthranilate synthase component II signature 482 496 4.4E-9 T 29-03-2018 SMALA_RS10400 c97614e13b74c0db14f70b0cdc19aad8 673 PRINTS PR00096 Glutamine amidotransferase superfamily signature 647 660 1.2E-9 T 29-03-2018 SMALA_RS10400 c97614e13b74c0db14f70b0cdc19aad8 673 PRINTS PR00096 Glutamine amidotransferase superfamily signature 527 536 1.2E-9 T 29-03-2018 SMALA_RS10400 c97614e13b74c0db14f70b0cdc19aad8 673 PRINTS PR00096 Glutamine amidotransferase superfamily signature 561 572 1.2E-9 T 29-03-2018 SMALA_RS10400 c97614e13b74c0db14f70b0cdc19aad8 673 SUPERFAMILY SSF52317 482 670 2.65E-20 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS10400 c97614e13b74c0db14f70b0cdc19aad8 673 Pfam PF00425 chorismate binding enzyme 127 409 6.5E-36 T 29-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal SMALA_RS10400 c97614e13b74c0db14f70b0cdc19aad8 673 Gene3D G3DSA:3.40.50.880 481 672 2.7E-26 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS10400 c97614e13b74c0db14f70b0cdc19aad8 673 Gene3D G3DSA:3.60.120.10 1 420 3.2E-77 T 29-03-2018 IPR005801 ADC synthase GO:0009058 SMALA_RS22635 e0d19e8b02047d853695dada014cf364 154 Gene3D G3DSA:3.100.10.10 46 153 5.6E-29 T 29-03-2018 SMALA_RS22635 e0d19e8b02047d853695dada014cf364 154 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 12 153 18.822 T 29-03-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 SMALA_RS22635 e0d19e8b02047d853695dada014cf364 154 ProSitePatterns PS00475 Ribosomal protein L15 signature. 117 147 - T 29-03-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMALA_RS22635 e0d19e8b02047d853695dada014cf364 154 SUPERFAMILY SSF52080 13 152 1.57E-40 T 29-03-2018 IPR021131 Ribosomal protein L18e/L15P SMALA_RS22635 e0d19e8b02047d853695dada014cf364 154 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 35 151 3.2E-33 T 29-03-2018 IPR021131 Ribosomal protein L18e/L15P SMALA_RS22635 e0d19e8b02047d853695dada014cf364 154 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 11 150 4.8E-45 T 29-03-2018 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS10575 3b14639b31605b4a24298a38239d8ef2 324 SUPERFAMILY SSF53613 2 295 1.11E-53 T 29-03-2018 IPR029056 Ribokinase-like SMALA_RS10575 3b14639b31605b4a24298a38239d8ef2 324 Gene3D G3DSA:3.40.1190.20 1 322 3.6E-43 T 29-03-2018 IPR029056 Ribokinase-like SMALA_RS10575 3b14639b31605b4a24298a38239d8ef2 324 Pfam PF00294 pfkB family carbohydrate kinase 32 295 4.3E-40 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB SMALA_RS24035 75cbf53c9640ca4693c529042df8da38 906 Hamap MF_00595 Phosphoenolpyruvate carboxylase [ppc]. 3 906 18.046 T 29-03-2018 IPR022805 Phosphoenolpyruvate carboxylase, bacterial/plant-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 SMALA_RS24035 75cbf53c9640ca4693c529042df8da38 906 SUPERFAMILY SSF51621 13 906 3.92E-269 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SMALA_RS24035 75cbf53c9640ca4693c529042df8da38 906 ProSitePatterns PS00781 Phosphoenolpyruvate carboxylase active site 1. 128 139 - T 29-03-2018 IPR018129 Phosphoenolpyruvate carboxylase, Lys active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 SMALA_RS24035 75cbf53c9640ca4693c529042df8da38 906 Pfam PF00311 Phosphoenolpyruvate carboxylase 123 906 1.6E-283 T 29-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 SMALA_RS24035 75cbf53c9640ca4693c529042df8da38 906 ProSitePatterns PS00393 Phosphoenolpyruvate carboxylase active site 2. 555 567 - T 29-03-2018 IPR033129 Phosphoenolpyruvate carboxylase, His active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 SMALA_RS24035 75cbf53c9640ca4693c529042df8da38 906 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 176 192 4.1E-57 T 29-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 SMALA_RS24035 75cbf53c9640ca4693c529042df8da38 906 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 553 573 4.1E-57 T 29-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 SMALA_RS24035 75cbf53c9640ca4693c529042df8da38 906 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 732 758 4.1E-57 T 29-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 SMALA_RS24035 75cbf53c9640ca4693c529042df8da38 906 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 127 140 4.1E-57 T 29-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 SMALA_RS24035 75cbf53c9640ca4693c529042df8da38 906 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 234 249 4.1E-57 T 29-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 SMALA_RS24035 75cbf53c9640ca4693c529042df8da38 906 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 595 624 4.1E-57 T 29-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 SMALA_RS24035 75cbf53c9640ca4693c529042df8da38 906 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 389 409 4.1E-57 T 29-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 SMALA_RS24035 75cbf53c9640ca4693c529042df8da38 906 Gene3D G3DSA:1.20.1440.90 265 391 9.0E-25 T 29-03-2018 SMALA_RS41790 0f69e305123a53ceb3dba56a4b904b74 340 Pfam PF00795 Carbon-nitrogen hydrolase 6 275 1.6E-50 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMALA_RS41790 0f69e305123a53ceb3dba56a4b904b74 340 SUPERFAMILY SSF56317 4 302 7.59E-66 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMALA_RS41790 0f69e305123a53ceb3dba56a4b904b74 340 ProSitePatterns PS00921 Nitrilases / cyanide hydratase active site signature. 156 169 - T 29-03-2018 IPR000132 Nitrilase/cyanide hydratase, conserved site GO:0016810 SMALA_RS41790 0f69e305123a53ceb3dba56a4b904b74 340 Gene3D G3DSA:3.60.110.10 4 298 8.1E-55 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMALA_RS41790 0f69e305123a53ceb3dba56a4b904b74 340 ProSitePatterns PS00920 Nitrilases / cyanide hydratase signature 1. 37 52 - T 29-03-2018 IPR000132 Nitrilase/cyanide hydratase, conserved site GO:0016810 SMALA_RS37950 fb8e0a7c348b875e67e32b69e8ee0ffd 330 Gene3D G3DSA:3.30.390.50 222 330 4.0E-24 T 29-03-2018 SMALA_RS37950 fb8e0a7c348b875e67e32b69e8ee0ffd 330 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 227 319 2.0E-15 T 29-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal SMALA_RS37950 fb8e0a7c348b875e67e32b69e8ee0ffd 330 SUPERFAMILY SSF56176 1 219 1.8E-57 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SMALA_RS37950 fb8e0a7c348b875e67e32b69e8ee0ffd 330 Gene3D G3DSA:3.30.43.10 1 51 7.8E-18 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 SMALA_RS37950 fb8e0a7c348b875e67e32b69e8ee0ffd 330 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 3 219 1.3E-50 T 29-03-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 SMALA_RS37950 fb8e0a7c348b875e67e32b69e8ee0ffd 330 SMART SM01092 226 324 8.8E-27 T 29-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal SMALA_RS37950 fb8e0a7c348b875e67e32b69e8ee0ffd 330 SUPERFAMILY SSF55447 225 325 1.31E-23 T 29-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal SMALA_RS37950 fb8e0a7c348b875e67e32b69e8ee0ffd 330 Gene3D G3DSA:3.30.465.10 139 221 1.3E-10 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SMALA_RS37950 fb8e0a7c348b875e67e32b69e8ee0ffd 330 Gene3D G3DSA:3.30.465.10 54 131 1.6E-20 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SMALA_RS19270 d6114520c9880713bae7d6e2f8e50dd9 180 Pfam PF02627 Carboxymuconolactone decarboxylase family 44 127 4.1E-16 T 29-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SMALA_RS19270 d6114520c9880713bae7d6e2f8e50dd9 180 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 60 108 2.1E-17 T 29-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SMALA_RS19270 d6114520c9880713bae7d6e2f8e50dd9 180 SUPERFAMILY SSF69118 38 177 1.11E-38 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 SMALA_RS19270 d6114520c9880713bae7d6e2f8e50dd9 180 Gene3D G3DSA:1.20.1290.10 33 179 3.7E-34 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 SMALA_RS13305 4c060ff5c04eb998c66ee03e01b85dcc 337 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 70 331 1.2E-29 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 SMALA_RS13305 4c060ff5c04eb998c66ee03e01b85dcc 337 PIRSF PIRSF017082 1 337 5.8E-73 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 SMALA_RS13305 4c060ff5c04eb998c66ee03e01b85dcc 337 SUPERFAMILY SSF53850 74 289 3.4E-5 T 29-03-2018 SMALA_RS13305 4c060ff5c04eb998c66ee03e01b85dcc 337 Gene3D G3DSA:3.40.190.10 135 251 1.8E-10 T 29-03-2018 SMALA_RS37940 a0029c6a365cddb566613543f9ffca1e 177 SUPERFAMILY SSF47240 23 175 1.32E-33 T 29-03-2018 IPR009078 Ferritin-like superfamily SMALA_RS37940 a0029c6a365cddb566613543f9ffca1e 177 PIRSF PIRSF018063 12 177 8.2E-51 T 29-03-2018 IPR014490 DNA-binding protein from starved cells-like SMALA_RS37940 a0029c6a365cddb566613543f9ffca1e 177 Pfam PF00210 Ferritin-like domain 39 175 3.5E-28 T 29-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 SMALA_RS37940 a0029c6a365cddb566613543f9ffca1e 177 Gene3D G3DSA:1.20.1260.10 2 176 1.3E-38 T 29-03-2018 IPR012347 Ferritin-related SMALA_RS39240 b1cc7da987cba8099f5e4a41cd4804f9 355 SUPERFAMILY SSF46785 18 97 2.72E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS39240 b1cc7da987cba8099f5e4a41cd4804f9 355 Pfam PF16864 Dimerisation domain 29 100 1.0E-9 T 29-03-2018 IPR031725 Acetylserotonin O-methyltransferase, dimerisation domain SMALA_RS39240 b1cc7da987cba8099f5e4a41cd4804f9 355 SUPERFAMILY SSF53335 99 340 2.37E-41 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS39240 b1cc7da987cba8099f5e4a41cd4804f9 355 Pfam PF00891 O-methyltransferase 112 338 1.5E-28 T 29-03-2018 IPR001077 O-methyltransferase, family 2 GO:0008171 SMALA_RS39240 b1cc7da987cba8099f5e4a41cd4804f9 355 Gene3D G3DSA:3.40.50.150 97 343 4.4E-37 T 29-03-2018 SMALA_RS39240 b1cc7da987cba8099f5e4a41cd4804f9 355 PIRSF PIRSF005739 9 346 5.1E-24 T 29-03-2018 IPR016461 O-methyltransferase COMT-type GO:0008168 SMALA_RS39240 b1cc7da987cba8099f5e4a41cd4804f9 355 Gene3D G3DSA:1.10.10.10 14 96 1.7E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS10920 ca443fccf64020ee544dcdd1adb57df6 106 Gene3D G3DSA:2.30.110.10 4 100 1.2E-9 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS10920 ca443fccf64020ee544dcdd1adb57df6 106 Pfam PF04075 F420H(2)-dependent quinone reductase 9 61 2.1E-4 T 29-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 SMALA_RS32390 c60650736fb7cd2c1919b3ef23861f4d 761 SUPERFAMILY SSF110296 37 442 5.62E-84 T 29-03-2018 SMALA_RS32390 c60650736fb7cd2c1919b3ef23861f4d 761 SUPERFAMILY SSF110296 450 758 9.55E-43 T 29-03-2018 SMALA_RS32390 c60650736fb7cd2c1919b3ef23861f4d 761 Gene3D G3DSA:2.130.10.10 452 761 7.2E-65 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMALA_RS32390 c60650736fb7cd2c1919b3ef23861f4d 761 Gene3D G3DSA:2.130.10.10 47 451 7.8E-83 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMALA_RS21200 e75f3f7af938e6d5113e64b06eb58e83 410 Gene3D G3DSA:3.30.9.10 95 169 3.7E-9 T 29-03-2018 SMALA_RS21200 e75f3f7af938e6d5113e64b06eb58e83 410 Gene3D G3DSA:3.50.50.60 2 94 5.9E-5 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS21200 e75f3f7af938e6d5113e64b06eb58e83 410 Pfam PF01266 FAD dependent oxidoreductase 7 396 5.6E-65 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 SMALA_RS21200 e75f3f7af938e6d5113e64b06eb58e83 410 Gene3D G3DSA:3.30.9.10 170 352 1.9E-34 T 29-03-2018 SMALA_RS21200 e75f3f7af938e6d5113e64b06eb58e83 410 SUPERFAMILY SSF51905 5 305 1.0E-47 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS06670 4a7152770e4d0f19515d60b94aa1cede 512 Gene3D G3DSA:3.50.50.60 1 386 4.0E-64 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS06670 4a7152770e4d0f19515d60b94aa1cede 512 SUPERFAMILY SSF51905 3 169 2.74E-63 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS06670 4a7152770e4d0f19515d60b94aa1cede 512 SUPERFAMILY SSF51905 257 346 2.74E-63 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS06670 4a7152770e4d0f19515d60b94aa1cede 512 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 148 163 5.3E-46 T 29-03-2018 SMALA_RS06670 4a7152770e4d0f19515d60b94aa1cede 512 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 5.3E-46 T 29-03-2018 SMALA_RS06670 4a7152770e4d0f19515d60b94aa1cede 512 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 303 321 5.3E-46 T 29-03-2018 SMALA_RS06670 4a7152770e4d0f19515d60b94aa1cede 512 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 285 301 5.3E-46 T 29-03-2018 SMALA_RS06670 4a7152770e4d0f19515d60b94aa1cede 512 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 321 337 5.3E-46 T 29-03-2018 SMALA_RS06670 4a7152770e4d0f19515d60b94aa1cede 512 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 270 285 5.3E-46 T 29-03-2018 SMALA_RS06670 4a7152770e4d0f19515d60b94aa1cede 512 Pfam PF01494 FAD binding domain 3 335 7.9E-89 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 SMALA_RS04890 d9165d8815189f248be3361a19795f2c 341 Gene3D G3DSA:3.10.180.10 144 303 2.1E-19 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS04890 d9165d8815189f248be3361a19795f2c 341 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 153 277 4.6E-13 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMALA_RS04890 d9165d8815189f248be3361a19795f2c 341 SUPERFAMILY SSF54593 12 135 7.19E-16 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS04890 d9165d8815189f248be3361a19795f2c 341 Gene3D G3DSA:3.10.180.10 15 141 3.1E-6 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS04890 d9165d8815189f248be3361a19795f2c 341 SUPERFAMILY SSF54593 145 303 4.64E-23 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS18965 804f3720af2124ed107d6568eca4f840 474 Pfam PF01425 Amidase 29 453 1.6E-107 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMALA_RS18965 804f3720af2124ed107d6568eca4f840 474 ProSitePatterns PS00571 Amidases signature. 156 187 - T 29-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 SMALA_RS18965 804f3720af2124ed107d6568eca4f840 474 SUPERFAMILY SSF75304 7 470 2.35E-137 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMALA_RS18965 804f3720af2124ed107d6568eca4f840 474 Gene3D G3DSA:3.90.1300.10 4 473 1.6E-139 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMALA_RS00090 2381fa6d9c4cbdcf5f4e5f0245c462a3 392 SMART SM00729 61 275 0.0052 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 SMALA_RS00090 2381fa6d9c4cbdcf5f4e5f0245c462a3 392 Gene3D G3DSA:3.20.20.70 5 375 2.4E-45 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS00090 2381fa6d9c4cbdcf5f4e5f0245c462a3 392 PIRSF PIRSF004762 2 385 7.0E-101 T 29-03-2018 SMALA_RS00090 2381fa6d9c4cbdcf5f4e5f0245c462a3 392 Pfam PF04055 Radical SAM superfamily 66 236 3.2E-11 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 SMALA_RS00090 2381fa6d9c4cbdcf5f4e5f0245c462a3 392 TIGRFAM TIGR00423 TIGR00423: radical SAM domain protein, CofH subfamily 57 373 3.3E-92 T 29-03-2018 IPR020050 FO synthase, subunit 2 GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 SMALA_RS00090 2381fa6d9c4cbdcf5f4e5f0245c462a3 392 Hamap MF_00993 Aminodeoxyfutalosine synthase [mqnE]. 12 376 48.395 T 29-03-2018 IPR022432 Aminodeoxyfutalosine synthase GO:0009234 KEGG: 00130+2.5.1.120|MetaCyc: PWY-7371|MetaCyc: PWY-7374 SMALA_RS00090 2381fa6d9c4cbdcf5f4e5f0245c462a3 392 SUPERFAMILY SSF102114 21 366 4.71E-44 T 29-03-2018 SMALA_RS00090 2381fa6d9c4cbdcf5f4e5f0245c462a3 392 TIGRFAM TIGR03700 mena_SCO4494: putative menaquinone biosynthesis radical SAM enzyme, SCO4494 family 15 373 2.2E-163 T 29-03-2018 IPR022432 Aminodeoxyfutalosine synthase GO:0009234 KEGG: 00130+2.5.1.120|MetaCyc: PWY-7371|MetaCyc: PWY-7374 SMALA_RS22000 2381fa6d9c4cbdcf5f4e5f0245c462a3 392 SMART SM00729 61 275 0.0052 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 SMALA_RS22000 2381fa6d9c4cbdcf5f4e5f0245c462a3 392 Gene3D G3DSA:3.20.20.70 5 375 2.4E-45 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS22000 2381fa6d9c4cbdcf5f4e5f0245c462a3 392 PIRSF PIRSF004762 2 385 7.0E-101 T 29-03-2018 SMALA_RS22000 2381fa6d9c4cbdcf5f4e5f0245c462a3 392 Pfam PF04055 Radical SAM superfamily 66 236 3.2E-11 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 SMALA_RS22000 2381fa6d9c4cbdcf5f4e5f0245c462a3 392 TIGRFAM TIGR00423 TIGR00423: radical SAM domain protein, CofH subfamily 57 373 3.3E-92 T 29-03-2018 IPR020050 FO synthase, subunit 2 GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 SMALA_RS22000 2381fa6d9c4cbdcf5f4e5f0245c462a3 392 Hamap MF_00993 Aminodeoxyfutalosine synthase [mqnE]. 12 376 48.395 T 29-03-2018 IPR022432 Aminodeoxyfutalosine synthase GO:0009234 KEGG: 00130+2.5.1.120|MetaCyc: PWY-7371|MetaCyc: PWY-7374 SMALA_RS22000 2381fa6d9c4cbdcf5f4e5f0245c462a3 392 SUPERFAMILY SSF102114 21 366 4.71E-44 T 29-03-2018 SMALA_RS22000 2381fa6d9c4cbdcf5f4e5f0245c462a3 392 TIGRFAM TIGR03700 mena_SCO4494: putative menaquinone biosynthesis radical SAM enzyme, SCO4494 family 15 373 2.2E-163 T 29-03-2018 IPR022432 Aminodeoxyfutalosine synthase GO:0009234 KEGG: 00130+2.5.1.120|MetaCyc: PWY-7371|MetaCyc: PWY-7374 SMALA_RS22555 63eb5431fe360262a0f2d7cfe7ea8d08 93 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 29-03-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMALA_RS22555 63eb5431fe360262a0f2d7cfe7ea8d08 93 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 1.4E-23 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMALA_RS22555 63eb5431fe360262a0f2d7cfe7ea8d08 93 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 1.4E-23 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMALA_RS22555 63eb5431fe360262a0f2d7cfe7ea8d08 93 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 1.4E-23 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMALA_RS22555 63eb5431fe360262a0f2d7cfe7ea8d08 93 Gene3D G3DSA:3.30.860.10 1 92 3.2E-39 T 29-03-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMALA_RS22555 63eb5431fe360262a0f2d7cfe7ea8d08 93 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 25.078 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMALA_RS22555 63eb5431fe360262a0f2d7cfe7ea8d08 93 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 92 5.7E-47 T 29-03-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 SMALA_RS22555 63eb5431fe360262a0f2d7cfe7ea8d08 93 Pfam PF00203 Ribosomal protein S19 3 83 2.1E-35 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMALA_RS22555 63eb5431fe360262a0f2d7cfe7ea8d08 93 PIRSF PIRSF002144 1 93 2.2E-30 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMALA_RS22555 63eb5431fe360262a0f2d7cfe7ea8d08 93 SUPERFAMILY SSF54570 3 85 1.01E-34 T 29-03-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMALA_RS36660 b58bfcaa2f10fbe03e4a765aa3370073 869 SUPERFAMILY SSF81923 48 152 8.76E-17 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 SMALA_RS36660 b58bfcaa2f10fbe03e4a765aa3370073 869 Gene3D G3DSA:3.40.50.300 533 756 8.6E-53 T 29-03-2018 SMALA_RS36660 b58bfcaa2f10fbe03e4a765aa3370073 869 SMART SM01086 757 846 3.6E-34 T 29-03-2018 IPR019489 Clp ATPase, C-terminal SMALA_RS36660 b58bfcaa2f10fbe03e4a765aa3370073 869 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 612 630 - T 29-03-2018 IPR028299 ClpA/B, conserved site 2 SMALA_RS36660 b58bfcaa2f10fbe03e4a765aa3370073 869 Gene3D G3DSA:3.40.50.300 199 386 2.8E-22 T 29-03-2018 SMALA_RS36660 b58bfcaa2f10fbe03e4a765aa3370073 869 SMART SM00382 239 387 3.2E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS36660 b58bfcaa2f10fbe03e4a765aa3370073 869 SMART SM00382 578 743 3.3E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS36660 b58bfcaa2f10fbe03e4a765aa3370073 869 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 338 350 - T 29-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 SMALA_RS36660 b58bfcaa2f10fbe03e4a765aa3370073 869 Pfam PF02151 UvrB/uvrC motif 460 492 9.5E-8 T 29-03-2018 IPR001943 UVR domain GO:0005515 SMALA_RS36660 b58bfcaa2f10fbe03e4a765aa3370073 869 Pfam PF07724 AAA domain (Cdc48 subfamily) 577 751 8.3E-53 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 SMALA_RS36660 b58bfcaa2f10fbe03e4a765aa3370073 869 Gene3D G3DSA:1.10.8.60 388 528 1.7E-39 T 29-03-2018 SMALA_RS36660 b58bfcaa2f10fbe03e4a765aa3370073 869 Gene3D G3DSA:1.10.8.60 757 857 1.9E-24 T 29-03-2018 SMALA_RS36660 b58bfcaa2f10fbe03e4a765aa3370073 869 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 130 171 2.0E-10 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 SMALA_RS36660 b58bfcaa2f10fbe03e4a765aa3370073 869 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 59 108 1.2E-6 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 SMALA_RS36660 b58bfcaa2f10fbe03e4a765aa3370073 869 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 757 837 4.3E-23 T 29-03-2018 IPR019489 Clp ATPase, C-terminal SMALA_RS36660 b58bfcaa2f10fbe03e4a765aa3370073 869 SUPERFAMILY SSF52540 200 471 2.04E-67 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS36660 b58bfcaa2f10fbe03e4a765aa3370073 869 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 656 674 1.1E-41 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 SMALA_RS36660 b58bfcaa2f10fbe03e4a765aa3370073 869 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 582 600 1.1E-41 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 SMALA_RS36660 b58bfcaa2f10fbe03e4a765aa3370073 869 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 627 645 1.1E-41 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 SMALA_RS36660 b58bfcaa2f10fbe03e4a765aa3370073 869 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 689 703 1.1E-41 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 SMALA_RS36660 b58bfcaa2f10fbe03e4a765aa3370073 869 Gene3D G3DSA:1.10.1780.10 46 172 3.9E-24 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 SMALA_RS36660 b58bfcaa2f10fbe03e4a765aa3370073 869 SUPERFAMILY SSF52540 527 847 4.85E-80 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS36660 b58bfcaa2f10fbe03e4a765aa3370073 869 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 244 364 6.9E-12 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 SMALA_RS10675 f009ee05b2fb98d6eeb260270d1fcbfd 321 Gene3D G3DSA:1.10.10.10 216 273 0.17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS10675 f009ee05b2fb98d6eeb260270d1fcbfd 321 PIRSF PIRSF016838 1 52 5.1E-5 T 29-03-2018 IPR028349 Protein PafC SMALA_RS10675 f009ee05b2fb98d6eeb260270d1fcbfd 321 PIRSF PIRSF016838 68 321 6.2E-14 T 29-03-2018 IPR028349 Protein PafC SMALA_RS10675 f009ee05b2fb98d6eeb260270d1fcbfd 321 SUPERFAMILY SSF46785 4 59 1.21E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS10675 f009ee05b2fb98d6eeb260270d1fcbfd 321 Gene3D G3DSA:1.10.10.10 2 64 2.7E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS10675 f009ee05b2fb98d6eeb260270d1fcbfd 321 Pfam PF13280 WYL domain 139 317 2.6E-43 T 29-03-2018 IPR026881 WYL domain SMALA_RS10675 f009ee05b2fb98d6eeb260270d1fcbfd 321 Pfam PF08279 HTH domain 5 60 4.8E-16 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 SMALA_RS41805 0b921031d587a4f27735fb660b96c067 233 Pfam PF16859 Bacterial transcriptional repressor C-terminal 115 225 1.8E-22 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS41805 0b921031d587a4f27735fb660b96c067 233 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 58 71 4.6E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS41805 0b921031d587a4f27735fb660b96c067 233 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 79 102 4.6E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS41805 0b921031d587a4f27735fb660b96c067 233 Gene3D G3DSA:1.10.357.10 99 233 5.7E-17 T 29-03-2018 SMALA_RS41805 0b921031d587a4f27735fb660b96c067 233 Gene3D G3DSA:1.10.10.60 43 98 1.8E-14 T 29-03-2018 SMALA_RS41805 0b921031d587a4f27735fb660b96c067 233 SUPERFAMILY SSF46689 49 111 6.98E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS41805 0b921031d587a4f27735fb660b96c067 233 SUPERFAMILY SSF48498 116 231 1.93E-21 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS41805 0b921031d587a4f27735fb660b96c067 233 Pfam PF00440 Bacterial regulatory proteins, tetR family 59 102 2.9E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS21305 731515a425a0c359da2c170e1e2234e0 237 SMART SM00014 68 179 1.3E-9 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMALA_RS21305 731515a425a0c359da2c170e1e2234e0 237 SUPERFAMILY SSF48317 11 182 1.44E-32 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMALA_RS21305 731515a425a0c359da2c170e1e2234e0 237 Gene3D G3DSA:1.20.144.10 11 198 4.5E-25 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMALA_RS21305 731515a425a0c359da2c170e1e2234e0 237 Pfam PF01569 PAP2 superfamily 72 179 3.2E-16 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMALA_RS18190 a895bbc551f7493c93d9db84ae9ef6f6 188 Pfam PF04978 Protein of unknown function (DUF664) 17 165 7.4E-41 T 29-03-2018 IPR007061 Protein of unknown function DUF664 SMALA_RS18190 a895bbc551f7493c93d9db84ae9ef6f6 188 Gene3D G3DSA:1.20.120.450 8 166 7.0E-33 T 29-03-2018 SMALA_RS18190 a895bbc551f7493c93d9db84ae9ef6f6 188 SUPERFAMILY SSF109854 4 164 1.14E-36 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes SMALA_RS04005 046db77893284b8d35bce2fef2b438c5 685 Gene3D G3DSA:3.20.20.70 36 199 1.1E-50 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS04005 046db77893284b8d35bce2fef2b438c5 685 SUPERFAMILY SSF51011 332 418 9.17E-20 T 29-03-2018 SMALA_RS04005 046db77893284b8d35bce2fef2b438c5 685 PRINTS PR00740 Glycosyl hydrolase family 27 signature 265 284 2.1E-57 T 29-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 SMALA_RS04005 046db77893284b8d35bce2fef2b438c5 685 PRINTS PR00740 Glycosyl hydrolase family 27 signature 54 73 2.1E-57 T 29-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 SMALA_RS04005 046db77893284b8d35bce2fef2b438c5 685 PRINTS PR00740 Glycosyl hydrolase family 27 signature 92 107 2.1E-57 T 29-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 SMALA_RS04005 046db77893284b8d35bce2fef2b438c5 685 PRINTS PR00740 Glycosyl hydrolase family 27 signature 169 186 2.1E-57 T 29-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 SMALA_RS04005 046db77893284b8d35bce2fef2b438c5 685 PRINTS PR00740 Glycosyl hydrolase family 27 signature 200 218 2.1E-57 T 29-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 SMALA_RS04005 046db77893284b8d35bce2fef2b438c5 685 PRINTS PR00740 Glycosyl hydrolase family 27 signature 286 307 2.1E-57 T 29-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 SMALA_RS04005 046db77893284b8d35bce2fef2b438c5 685 PRINTS PR00740 Glycosyl hydrolase family 27 signature 133 154 2.1E-57 T 29-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 SMALA_RS04005 046db77893284b8d35bce2fef2b438c5 685 Gene3D G3DSA:2.60.40.10 434 538 1.3E-8 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS04005 046db77893284b8d35bce2fef2b438c5 685 SUPERFAMILY SSF51445 52 331 3.26E-97 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS04005 046db77893284b8d35bce2fef2b438c5 685 Pfam PF16499 Alpha galactosidase A 59 330 8.9E-80 T 29-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 SMALA_RS04005 046db77893284b8d35bce2fef2b438c5 685 Pfam PF08305 NPCBM/NEW2 domain 544 684 1.2E-49 T 29-03-2018 IPR013222 Glycosyl hydrolase family 98, putative carbohydrate-binding module SMALA_RS04005 046db77893284b8d35bce2fef2b438c5 685 Pfam PF10633 NPCBM-associated, NEW3 domain of alpha-galactosidase 441 517 1.4E-20 T 29-03-2018 IPR018905 Alpha-galactosidase, NEW3 domain SMALA_RS04005 046db77893284b8d35bce2fef2b438c5 685 Gene3D G3DSA:2.60.40.1180 333 420 1.5E-21 T 29-03-2018 SMALA_RS04005 046db77893284b8d35bce2fef2b438c5 685 Gene3D G3DSA:3.20.20.70 200 332 1.8E-56 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS04005 046db77893284b8d35bce2fef2b438c5 685 SMART SM00776 540 685 6.1E-74 T 29-03-2018 IPR013222 Glycosyl hydrolase family 98, putative carbohydrate-binding module SMALA_RS04005 046db77893284b8d35bce2fef2b438c5 685 ProSitePatterns PS00512 Alpha-galactosidase signature. 97 113 - T 29-03-2018 IPR000111 Glycoside hydrolase family 27/36, conserved site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 SMALA_RS04005 046db77893284b8d35bce2fef2b438c5 685 SUPERFAMILY SSF49785 542 685 4.0E-45 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS05500 c138bb8423629722661f80e6d1f19cf5 470 Gene3D G3DSA:3.40.50.1820 43 404 5.4E-18 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS05500 c138bb8423629722661f80e6d1f19cf5 470 SUPERFAMILY SSF53474 48 180 2.77E-15 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS05500 c138bb8423629722661f80e6d1f19cf5 470 SUPERFAMILY SSF53474 207 235 2.77E-15 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS05500 c138bb8423629722661f80e6d1f19cf5 470 SUPERFAMILY SSF53474 309 355 2.77E-15 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS31485 628dcfc33782100d69fd8f35a28ac020 854 SMART SM00729 65 302 2.6E-7 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 SMALA_RS31485 628dcfc33782100d69fd8f35a28ac020 854 TIGRFAM TIGR00423 TIGR00423: radical SAM domain protein, CofH subfamily 520 828 8.5E-109 T 29-03-2018 IPR020050 FO synthase, subunit 2 GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 SMALA_RS31485 628dcfc33782100d69fd8f35a28ac020 854 Hamap MF_01612 FO synthase subunit 2 [cofH]. 467 831 48.382 T 29-03-2018 IPR019940 CofH family GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 SMALA_RS31485 628dcfc33782100d69fd8f35a28ac020 854 TIGRFAM TIGR03550 F420_cofG: 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofG subunit 62 390 1.3E-141 T 29-03-2018 IPR019939 CofG family GO:0009108|GO:0016765|GO:0051539 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 SMALA_RS31485 628dcfc33782100d69fd8f35a28ac020 854 Pfam PF04055 Radical SAM superfamily 69 251 2.2E-13 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 SMALA_RS31485 628dcfc33782100d69fd8f35a28ac020 854 Pfam PF04055 Radical SAM superfamily 528 688 9.0E-15 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 SMALA_RS31485 628dcfc33782100d69fd8f35a28ac020 854 Gene3D G3DSA:3.20.20.70 462 832 4.9E-51 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS31485 628dcfc33782100d69fd8f35a28ac020 854 Gene3D G3DSA:3.20.20.70 2 375 5.1E-32 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS31485 628dcfc33782100d69fd8f35a28ac020 854 SUPERFAMILY SSF102114 483 794 2.09E-49 T 29-03-2018 SMALA_RS31485 628dcfc33782100d69fd8f35a28ac020 854 TIGRFAM TIGR03551 F420_cofH: 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofH subunit 486 830 4.6E-161 T 29-03-2018 IPR019940 CofH family GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 SMALA_RS31485 628dcfc33782100d69fd8f35a28ac020 854 SUPERFAMILY SSF102114 22 367 1.67E-35 T 29-03-2018 SMALA_RS31485 628dcfc33782100d69fd8f35a28ac020 854 Hamap MF_01611 FO synthase subunit 1 [cofG]. 61 392 50.41 T 29-03-2018 IPR019939 CofG family GO:0009108|GO:0016765|GO:0051539 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 SMALA_RS28280 d6bc55a008b1a0f5b7ede6ead71132bc 241 SMART SM00382 34 222 9.0E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS28280 d6bc55a008b1a0f5b7ede6ead71132bc 241 Pfam PF00005 ABC transporter 27 174 7.8E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS28280 d6bc55a008b1a0f5b7ede6ead71132bc 241 SUPERFAMILY SSF52540 9 225 1.23E-51 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS28280 d6bc55a008b1a0f5b7ede6ead71132bc 241 Gene3D G3DSA:3.40.50.300 6 231 3.1E-53 T 29-03-2018 SMALA_RS39575 1287284c76f423391e2060ddda86a942 186 Pfam PF07884 Vitamin K epoxide reductase family 2 131 1.5E-34 T 29-03-2018 IPR012932 Vitamin K epoxide reductase Reactome: R-HSA-6806664 SMALA_RS39575 1287284c76f423391e2060ddda86a942 186 SMART SM00756 1 135 3.0E-43 T 29-03-2018 IPR012932 Vitamin K epoxide reductase Reactome: R-HSA-6806664 SMALA_RS35405 8a25ef1a9149c8003313a353241d71d6 397 SUPERFAMILY SSF50494 219 389 6.43E-33 T 29-03-2018 IPR009003 Peptidase S1, PA clan SMALA_RS35405 8a25ef1a9149c8003313a353241d71d6 397 Gene3D G3DSA:3.30.300.50 127 202 4.4E-15 T 29-03-2018 IPR035070 Streptogrisin prodomain SMALA_RS35405 8a25ef1a9149c8003313a353241d71d6 397 Gene3D G3DSA:2.40.10.10 294 382 2.8E-16 T 29-03-2018 SMALA_RS35405 8a25ef1a9149c8003313a353241d71d6 397 Gene3D G3DSA:2.40.10.10 213 293 6.0E-18 T 29-03-2018 SMALA_RS35405 8a25ef1a9149c8003313a353241d71d6 397 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 296 316 1.1E-39 T 29-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMALA_RS35405 8a25ef1a9149c8003313a353241d71d6 397 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 317 334 1.1E-39 T 29-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMALA_RS35405 8a25ef1a9149c8003313a353241d71d6 397 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 360 374 1.1E-39 T 29-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMALA_RS35405 8a25ef1a9149c8003313a353241d71d6 397 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 336 359 1.1E-39 T 29-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMALA_RS35405 8a25ef1a9149c8003313a353241d71d6 397 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 235 249 1.1E-39 T 29-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMALA_RS35405 8a25ef1a9149c8003313a353241d71d6 397 Gene3D G3DSA:3.30.300.50 49 126 6.4E-26 T 29-03-2018 IPR035070 Streptogrisin prodomain SMALA_RS35405 8a25ef1a9149c8003313a353241d71d6 397 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 345 356 - T 29-03-2018 IPR033116 Serine proteases, trypsin family, serine active site SMALA_RS35405 8a25ef1a9149c8003313a353241d71d6 397 PIRSF PIRSF001134 13 397 4.6E-122 T 29-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMALA_RS35405 8a25ef1a9149c8003313a353241d71d6 397 Pfam PF02983 Alpha-lytic protease prodomain 130 188 2.0E-9 T 29-03-2018 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 SMALA_RS35950 d51e0cd1faf39c889302b1db862a0167 324 SUPERFAMILY SSF51735 2 321 1.24E-98 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS35950 d51e0cd1faf39c889302b1db862a0167 324 Gene3D G3DSA:3.90.25.10 187 324 1.4E-48 T 29-03-2018 SMALA_RS35950 d51e0cd1faf39c889302b1db862a0167 324 Pfam PF16363 GDP-mannose 4,6 dehydratase 5 307 6.5E-80 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS35950 d51e0cd1faf39c889302b1db862a0167 324 Gene3D G3DSA:3.40.50.720 1 186 1.1E-43 T 29-03-2018 SMALA_RS35950 d51e0cd1faf39c889302b1db862a0167 324 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 2 321 6.8E-138 T 29-03-2018 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|KEGG: 00525+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 SMALA_RS06790 fad5752bcde20086d16f68c7a7ac7907 213 Pfam PF01965 DJ-1/PfpI family 3 162 3.5E-29 T 29-03-2018 IPR002818 DJ-1/PfpI SMALA_RS06790 fad5752bcde20086d16f68c7a7ac7907 213 SUPERFAMILY SSF52317 1 183 2.13E-46 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS06790 fad5752bcde20086d16f68c7a7ac7907 213 Gene3D G3DSA:3.40.50.880 1 212 3.1E-53 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS39740 c5033d34a7a13173455b575ad1511059 308 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 153 7.0E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS39740 c5033d34a7a13173455b575ad1511059 308 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 177 196 7.0E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS39740 c5033d34a7a13173455b575ad1511059 308 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 93 104 7.0E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS39740 c5033d34a7a13173455b575ad1511059 308 SUPERFAMILY SSF51735 13 261 3.01E-49 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS39740 c5033d34a7a13173455b575ad1511059 308 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 196 1.2E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS39740 c5033d34a7a13173455b575ad1511059 308 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 18 35 1.2E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS39740 c5033d34a7a13173455b575ad1511059 308 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 139 155 1.2E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS39740 c5033d34a7a13173455b575ad1511059 308 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 93 104 1.2E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS39740 c5033d34a7a13173455b575ad1511059 308 Pfam PF00106 short chain dehydrogenase 18 220 1.4E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS39740 c5033d34a7a13173455b575ad1511059 308 Gene3D G3DSA:3.40.50.720 2 305 5.0E-59 T 29-03-2018 SMALA_RS08920 aec79d0a1d84eb6f6c79f287145410ab 224 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 74 2.2E-20 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS08920 aec79d0a1d84eb6f6c79f287145410ab 224 Pfam PF07729 FCD domain 97 215 6.5E-26 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS08920 aec79d0a1d84eb6f6c79f287145410ab 224 Gene3D G3DSA:1.20.120.530 78 216 4.2E-30 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS08920 aec79d0a1d84eb6f6c79f287145410ab 224 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 5.1E-9 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS08920 aec79d0a1d84eb6f6c79f287145410ab 224 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 5.1E-9 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS08920 aec79d0a1d84eb6f6c79f287145410ab 224 SUPERFAMILY SSF46785 7 78 2.09E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS08920 aec79d0a1d84eb6f6c79f287145410ab 224 SMART SM00895 95 218 2.8E-20 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS08920 aec79d0a1d84eb6f6c79f287145410ab 224 SUPERFAMILY SSF48008 92 215 1.39E-25 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS08920 aec79d0a1d84eb6f6c79f287145410ab 224 SMART SM00345 15 74 5.9E-20 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS08920 aec79d0a1d84eb6f6c79f287145410ab 224 Gene3D G3DSA:1.10.10.10 3 76 7.8E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS13935 2779994e8238e5b7818c1f6ed7223a99 429 Pfam PF00285 Citrate synthase, C-terminal domain 46 412 1.2E-134 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 SMALA_RS13935 2779994e8238e5b7818c1f6ed7223a99 429 ProSitePatterns PS00480 Citrate synthase signature. 304 316 - T 29-03-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 SMALA_RS13935 2779994e8238e5b7818c1f6ed7223a99 429 PRINTS PR00143 Citrate synthase signature 297 317 2.7E-54 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 SMALA_RS13935 2779994e8238e5b7818c1f6ed7223a99 429 PRINTS PR00143 Citrate synthase signature 380 394 2.7E-54 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 SMALA_RS13935 2779994e8238e5b7818c1f6ed7223a99 429 PRINTS PR00143 Citrate synthase signature 219 234 2.7E-54 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 SMALA_RS13935 2779994e8238e5b7818c1f6ed7223a99 429 PRINTS PR00143 Citrate synthase signature 241 269 2.7E-54 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 SMALA_RS13935 2779994e8238e5b7818c1f6ed7223a99 429 PRINTS PR00143 Citrate synthase signature 165 178 2.7E-54 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 SMALA_RS13935 2779994e8238e5b7818c1f6ed7223a99 429 PRINTS PR00143 Citrate synthase signature 360 376 2.7E-54 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 SMALA_RS13935 2779994e8238e5b7818c1f6ed7223a99 429 Gene3D G3DSA:1.10.580.10 30 282 1.1E-89 T 29-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain SMALA_RS13935 2779994e8238e5b7818c1f6ed7223a99 429 SUPERFAMILY SSF48256 3 429 4.06E-160 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 SMALA_RS13935 2779994e8238e5b7818c1f6ed7223a99 429 PIRSF PIRSF001369 37 429 3.3E-155 T 29-03-2018 IPR024176 Citrate synthase, bacterial-type SMALA_RS13935 2779994e8238e5b7818c1f6ed7223a99 429 TIGRFAM TIGR01798 cit_synth_I: citrate (Si)-synthase 14 423 9.7E-184 T 29-03-2018 IPR010953 Citrate synthase, type I GO:0004108|GO:0005737 SMALA_RS13935 2779994e8238e5b7818c1f6ed7223a99 429 Gene3D G3DSA:1.10.230.10 283 380 2.1E-33 T 29-03-2018 IPR016143 Citrate synthase-like, small alpha subdomain SMALA_RS02550 f0a3c1e2926aa5bc5ede611e492945e1 117 Pfam PF00550 Phosphopantetheine attachment site 2 60 3.5E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS02550 f0a3c1e2926aa5bc5ede611e492945e1 117 SMART SM01294 7 60 3.5E-4 T 29-03-2018 SMALA_RS02550 f0a3c1e2926aa5bc5ede611e492945e1 117 SMART SM00823 Phosphopantetheine attachment site 2 64 7.1E-17 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS02550 f0a3c1e2926aa5bc5ede611e492945e1 117 Gene3D G3DSA:1.10.1200.10 1 73 1.0E-16 T 29-03-2018 SMALA_RS02550 f0a3c1e2926aa5bc5ede611e492945e1 117 ProSitePatterns PS00012 Phosphopantetheine attachment site. 19 34 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS02550 f0a3c1e2926aa5bc5ede611e492945e1 117 SUPERFAMILY SSF47336 2 72 3.53E-17 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS36750 5c8d2d44dc6814baa4a73ac558458d6a 155 Gene3D G3DSA:3.10.450.50 1 135 2.1E-18 T 29-03-2018 SMALA_RS36750 5c8d2d44dc6814baa4a73ac558458d6a 155 Pfam PF12680 SnoaL-like domain 13 110 3.6E-13 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain SMALA_RS36750 5c8d2d44dc6814baa4a73ac558458d6a 155 SUPERFAMILY SSF54427 1 119 2.54E-23 T 29-03-2018 IPR032710 NTF2-like domain SMALA_RS22325 72789e5907ad77a6fbb8deb5422f9897 162 Pfam PF04461 Protein of unknown function (DUF520) 4 162 1.7E-61 T 29-03-2018 IPR007551 Protein of unknown function DUF520 SMALA_RS22325 72789e5907ad77a6fbb8deb5422f9897 162 Gene3D G3DSA:3.30.70.990 12 96 6.6E-33 T 29-03-2018 IPR035570 UPF0234 N-terminal domain SMALA_RS22325 72789e5907ad77a6fbb8deb5422f9897 162 Hamap MF_00632 UPF0234 protein YajQ [yajQ]. 3 162 25.976 T 29-03-2018 IPR007551 Protein of unknown function DUF520 SMALA_RS22325 72789e5907ad77a6fbb8deb5422f9897 162 SUPERFAMILY SSF89963 5 88 1.39E-28 T 29-03-2018 IPR007551 Protein of unknown function DUF520 SMALA_RS22325 72789e5907ad77a6fbb8deb5422f9897 162 SUPERFAMILY SSF89963 90 162 4.71E-24 T 29-03-2018 IPR007551 Protein of unknown function DUF520 SMALA_RS22325 72789e5907ad77a6fbb8deb5422f9897 162 Gene3D G3DSA:3.30.70.860 97 162 1.1E-29 T 29-03-2018 IPR035571 UPF0234/UPF0381 domain SMALA_RS07995 1df558f9e0c098170f64713a1c005ae9 348 Gene3D G3DSA:3.40.430.10 37 265 2.2E-53 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 SMALA_RS07995 1df558f9e0c098170f64713a1c005ae9 348 Pfam PF01872 RibD C-terminal domain 64 232 9.5E-37 T 29-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 SMALA_RS07995 1df558f9e0c098170f64713a1c005ae9 348 SUPERFAMILY SSF53597 63 246 4.83E-46 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 SMALA_RS27510 daaaa8ec76bd4836c9543e19d9063472 460 Gene3D G3DSA:1.10.4100.10 250 450 1.9E-33 T 29-03-2018 SMALA_RS27510 daaaa8ec76bd4836c9543e19d9063472 460 SUPERFAMILY SSF143548 17 164 1.02E-43 T 29-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 SMALA_RS27510 daaaa8ec76bd4836c9543e19d9063472 460 Pfam PF03313 Serine dehydratase alpha chain 193 454 2.2E-103 T 29-03-2018 IPR005130 Serine dehydratase-like, alpha subunit SMALA_RS27510 daaaa8ec76bd4836c9543e19d9063472 460 TIGRFAM TIGR00720 sda_mono: L-serine ammonia-lyase 3 457 1.3E-207 T 29-03-2018 IPR004644 Iron-sulphur-dependent L-serine dehydratase single chain form GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 SMALA_RS27510 daaaa8ec76bd4836c9543e19d9063472 460 Gene3D G3DSA:3.30.1330.90 11 165 2.0E-56 T 29-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 SMALA_RS27510 daaaa8ec76bd4836c9543e19d9063472 460 Pfam PF03315 Serine dehydratase beta chain 4 162 1.2E-58 T 29-03-2018 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 SMALA_RS29385 38f3e2c534189e4d66c9b150cb8a02ed 262 SUPERFAMILY SSF46894 195 251 7.48E-9 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS29385 38f3e2c534189e4d66c9b150cb8a02ed 262 SMART SM00421 195 244 0.0015 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS29385 38f3e2c534189e4d66c9b150cb8a02ed 262 Gene3D G3DSA:1.10.10.10 65 249 2.0E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS05690 cb0cfa95a4159f2f4d7290849b10ffaa 428 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 13 417 1.4E-7 T 29-03-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit SMALA_RS31930 4d9b37af612781d44857f0bb8d794534 312 PIRSF PIRSF001365 4 311 1.2E-68 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SMALA_RS31930 4d9b37af612781d44857f0bb8d794534 312 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 138 168 - T 29-03-2018 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 SMALA_RS31930 4d9b37af612781d44857f0bb8d794534 312 Pfam PF00701 Dihydrodipicolinate synthetase family 7 305 2.8E-43 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SMALA_RS31930 4d9b37af612781d44857f0bb8d794534 312 SUPERFAMILY SSF51569 4 311 4.61E-71 T 29-03-2018 SMALA_RS31930 4d9b37af612781d44857f0bb8d794534 312 SMART SM01130 6 309 1.3E-75 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SMALA_RS31930 4d9b37af612781d44857f0bb8d794534 312 Gene3D G3DSA:3.20.20.70 1 312 8.3E-78 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS31930 4d9b37af612781d44857f0bb8d794534 312 PRINTS PR00146 Dihydrodipicolinate synthase signature 40 61 1.8E-7 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SMALA_RS31930 4d9b37af612781d44857f0bb8d794534 312 PRINTS PR00146 Dihydrodipicolinate synthase signature 76 94 1.8E-7 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SMALA_RS31930 4d9b37af612781d44857f0bb8d794534 312 PRINTS PR00146 Dihydrodipicolinate synthase signature 108 124 1.8E-7 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SMALA_RS31930 4d9b37af612781d44857f0bb8d794534 312 PRINTS PR00146 Dihydrodipicolinate synthase signature 133 150 1.8E-7 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SMALA_RS23810 691037aa24b7a116fc3e2d1642853503 228 SUPERFAMILY SSF46955 2 79 1.92E-17 T 29-03-2018 IPR009061 Putative DNA-binding domain SMALA_RS23810 691037aa24b7a116fc3e2d1642853503 228 SMART SM00422 1 67 4.8E-12 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS23810 691037aa24b7a116fc3e2d1642853503 228 Pfam PF13411 MerR HTH family regulatory protein 1 65 2.8E-18 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS23810 691037aa24b7a116fc3e2d1642853503 228 Gene3D G3DSA:1.10.1660.10 1 220 2.4E-21 T 29-03-2018 SMALA_RS11635 bf3423ffb378a6ddc690cf09a38dd75e 188 Gene3D G3DSA:3.40.630.30 24 187 1.4E-24 T 29-03-2018 SMALA_RS11635 bf3423ffb378a6ddc690cf09a38dd75e 188 SUPERFAMILY SSF55729 41 185 1.36E-25 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS11635 bf3423ffb378a6ddc690cf09a38dd75e 188 Pfam PF00583 Acetyltransferase (GNAT) family 74 167 7.4E-15 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SMALA_RS39565 306638f2d248d1e8c6bd2663c339c9cd 230 SUPERFAMILY SSF52172 12 141 8.82E-29 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS39565 306638f2d248d1e8c6bd2663c339c9cd 230 SMART SM00421 161 218 2.3E-24 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS39565 306638f2d248d1e8c6bd2663c339c9cd 230 Gene3D G3DSA:1.10.10.10 145 223 1.4E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS39565 306638f2d248d1e8c6bd2663c339c9cd 230 SMART SM00448 13 126 2.6E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS39565 306638f2d248d1e8c6bd2663c339c9cd 230 ProSitePatterns PS00622 LuxR-type HTH domain signature. 178 205 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS39565 306638f2d248d1e8c6bd2663c339c9cd 230 Pfam PF00072 Response regulator receiver domain 15 126 7.0E-23 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS39565 306638f2d248d1e8c6bd2663c339c9cd 230 Pfam PF00196 Bacterial regulatory proteins, luxR family 164 218 4.6E-16 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS39565 306638f2d248d1e8c6bd2663c339c9cd 230 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 178 1.3E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS39565 306638f2d248d1e8c6bd2663c339c9cd 230 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 178 194 1.3E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS39565 306638f2d248d1e8c6bd2663c339c9cd 230 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 194 206 1.3E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS39565 306638f2d248d1e8c6bd2663c339c9cd 230 SUPERFAMILY SSF46894 155 220 6.8E-20 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS39565 306638f2d248d1e8c6bd2663c339c9cd 230 Gene3D G3DSA:3.40.50.2300 12 144 8.1E-33 T 29-03-2018 SMALA_RS04195 5c3e8d2e5ac37277bf5862ce4af89d6b 200 Pfam PF17197 Domain of unknown function (DUF5134) 35 200 2.6E-37 T 29-03-2018 IPR033458 Protein of unknown function DUF5134 SMALA_RS03510 d117da814573aa8109fa7d3c4c196bb4 361 Gene3D G3DSA:3.40.50.10730 174 298 5.2E-36 T 29-03-2018 SMALA_RS03510 d117da814573aa8109fa7d3c4c196bb4 361 SUPERFAMILY SSF50129 310 360 3.95E-6 T 29-03-2018 IPR011032 GroES-like SMALA_RS03510 d117da814573aa8109fa7d3c4c196bb4 361 SMART SM00829 14 361 3.8E-5 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS03510 d117da814573aa8109fa7d3c4c196bb4 361 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 30 147 3.4E-26 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS03510 d117da814573aa8109fa7d3c4c196bb4 361 SUPERFAMILY SSF50129 4 186 3.62E-54 T 29-03-2018 IPR011032 GroES-like SMALA_RS03510 d117da814573aa8109fa7d3c4c196bb4 361 Pfam PF00107 Zinc-binding dehydrogenase 190 319 2.5E-26 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMALA_RS03510 d117da814573aa8109fa7d3c4c196bb4 361 Gene3D G3DSA:3.90.180.10 6 173 4.2E-46 T 29-03-2018 SMALA_RS03510 d117da814573aa8109fa7d3c4c196bb4 361 SUPERFAMILY SSF51735 154 324 4.24E-43 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS03510 d117da814573aa8109fa7d3c4c196bb4 361 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 SMALA_RS03510 d117da814573aa8109fa7d3c4c196bb4 361 TIGRFAM TIGR03451 mycoS_dep_FDH: S-(hydroxymethyl)mycothiol dehydrogenase 5 361 1.3E-195 T 29-03-2018 IPR017816 S-(hydroxymethyl)mycothiol dehydrogenase KEGG: 00072+1.1.1.30|KEGG: 00650+1.1.1.30 SMALA_RS39290 d9938accb43e4eba94d980f2b4072768 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 2.5E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS39290 d9938accb43e4eba94d980f2b4072768 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 2.5E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS39290 d9938accb43e4eba94d980f2b4072768 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 64 7.2E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS39290 d9938accb43e4eba94d980f2b4072768 202 Gene3D G3DSA:1.10.357.10 66 198 5.4E-25 T 29-03-2018 SMALA_RS39290 d9938accb43e4eba94d980f2b4072768 202 SUPERFAMILY SSF48498 85 200 6.85E-28 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS39290 d9938accb43e4eba94d980f2b4072768 202 ProSitePatterns PS01081 TetR-type HTH domain signature. 32 62 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site SMALA_RS39290 d9938accb43e4eba94d980f2b4072768 202 Gene3D G3DSA:1.10.10.60 3 65 2.1E-16 T 29-03-2018 SMALA_RS39290 d9938accb43e4eba94d980f2b4072768 202 SUPERFAMILY SSF46689 9 75 6.98E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS36510 1df492580f0009c7d9ca99baee981101 96 ProDom PD280340 RV1738/MT1780 MB2665C MB1767 SCO3163 RV2632C/MT2708 7 77 4.0E-11 T 29-03-2018 IPR015057 Protein of unknown function DUF1876 SMALA_RS36510 1df492580f0009c7d9ca99baee981101 96 SUPERFAMILY SSF143212 2 79 1.44E-23 T 29-03-2018 SMALA_RS36510 1df492580f0009c7d9ca99baee981101 96 Pfam PF08962 Domain of unknown function (DUF1876) 6 83 1.0E-29 T 29-03-2018 IPR015057 Protein of unknown function DUF1876 SMALA_RS09935 e8e9f02e12fe36df4f2992fa785a7b9f 1516 SUPERFAMILY SSF69336 1224 1489 4.58E-87 T 29-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 SMALA_RS09935 e8e9f02e12fe36df4f2992fa785a7b9f 1516 SUPERFAMILY SSF51395 447 1211 9.77E-262 T 29-03-2018 SMALA_RS09935 e8e9f02e12fe36df4f2992fa785a7b9f 1516 Pfam PF04898 Glutamate synthase central domain 458 747 1.4E-111 T 29-03-2018 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 SMALA_RS09935 e8e9f02e12fe36df4f2992fa785a7b9f 1516 Gene3D G3DSA:3.20.20.70 443 792 2.1E-100 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS09935 e8e9f02e12fe36df4f2992fa785a7b9f 1516 Pfam PF01493 GXGXG motif 1260 1431 1.8E-75 T 29-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 SMALA_RS09935 e8e9f02e12fe36df4f2992fa785a7b9f 1516 Pfam PF00310 Glutamine amidotransferases class-II 22 432 1.1E-180 T 29-03-2018 IPR017932 Glutamine amidotransferase type 2 domain SMALA_RS09935 e8e9f02e12fe36df4f2992fa785a7b9f 1516 Gene3D G3DSA:3.60.20.10 22 442 7.0E-170 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SMALA_RS09935 e8e9f02e12fe36df4f2992fa785a7b9f 1516 SUPERFAMILY SSF56235 22 434 2.67E-149 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SMALA_RS09935 e8e9f02e12fe36df4f2992fa785a7b9f 1516 Gene3D G3DSA:3.20.20.70 793 1227 4.9E-160 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS09935 e8e9f02e12fe36df4f2992fa785a7b9f 1516 Pfam PF01645 Conserved region in glutamate synthase 811 1175 1.7E-155 T 29-03-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 SMALA_RS09935 e8e9f02e12fe36df4f2992fa785a7b9f 1516 Gene3D G3DSA:2.160.20.60 1230 1506 2.3E-107 T 29-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 SMALA_RS34225 6c304b440dc937072892dd52e9b55efb 438 Gene3D G3DSA:3.40.190.10 175 438 2.7E-40 T 29-03-2018 SMALA_RS34225 6c304b440dc937072892dd52e9b55efb 438 Pfam PF01547 Bacterial extracellular solute-binding protein 57 347 1.6E-36 T 29-03-2018 IPR006059 Solute-binding family 1 GO:0006810 SMALA_RS34225 6c304b440dc937072892dd52e9b55efb 438 Gene3D G3DSA:3.40.190.10 39 174 0.0081 T 29-03-2018 SMALA_RS34225 6c304b440dc937072892dd52e9b55efb 438 SUPERFAMILY SSF53850 46 431 1.41E-72 T 29-03-2018 SMALA_RS11300 efbc51c583cb33785bc099380679307c 226 SMART SM00421 159 216 3.9E-23 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS11300 efbc51c583cb33785bc099380679307c 226 Pfam PF00072 Response regulator receiver domain 8 122 4.3E-23 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS11300 efbc51c583cb33785bc099380679307c 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 192 204 5.7E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS11300 efbc51c583cb33785bc099380679307c 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 176 192 5.7E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS11300 efbc51c583cb33785bc099380679307c 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 162 176 5.7E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS11300 efbc51c583cb33785bc099380679307c 226 Gene3D G3DSA:1.10.10.10 140 221 6.2E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS11300 efbc51c583cb33785bc099380679307c 226 ProSitePatterns PS00622 LuxR-type HTH domain signature. 176 203 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS11300 efbc51c583cb33785bc099380679307c 226 Pfam PF00196 Bacterial regulatory proteins, luxR family 162 216 2.4E-18 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS11300 efbc51c583cb33785bc099380679307c 226 SUPERFAMILY SSF52172 5 184 1.87E-30 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS11300 efbc51c583cb33785bc099380679307c 226 SMART SM00448 6 121 5.1E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS11300 efbc51c583cb33785bc099380679307c 226 Gene3D G3DSA:3.40.50.2300 5 139 4.0E-34 T 29-03-2018 SMALA_RS23120 f774c93e1d7658b9c1a498fcd5f30e82 215 Pfam PF00440 Bacterial regulatory proteins, tetR family 31 62 1.3E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS23120 f774c93e1d7658b9c1a498fcd5f30e82 215 Gene3D G3DSA:1.10.357.10 73 208 1.8E-9 T 29-03-2018 SMALA_RS23120 f774c93e1d7658b9c1a498fcd5f30e82 215 SUPERFAMILY SSF48498 93 205 6.5E-10 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS23120 f774c93e1d7658b9c1a498fcd5f30e82 215 Gene3D G3DSA:1.10.10.60 9 72 2.6E-15 T 29-03-2018 SMALA_RS23120 f774c93e1d7658b9c1a498fcd5f30e82 215 SUPERFAMILY SSF46689 15 76 3.02E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS01660 115a1652efcb0f4147e2880e6b08efab 135 Pfam PF13474 SnoaL-like domain 5 126 1.2E-16 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain SMALA_RS01660 115a1652efcb0f4147e2880e6b08efab 135 Gene3D G3DSA:3.10.450.50 2 135 1.1E-17 T 29-03-2018 SMALA_RS01660 115a1652efcb0f4147e2880e6b08efab 135 SUPERFAMILY SSF54427 3 124 7.4E-21 T 29-03-2018 IPR032710 NTF2-like domain SMALA_RS38185 e33c91f3baebe501cb890565ea39711a 313 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS38185 e33c91f3baebe501cb890565ea39711a 313 SUPERFAMILY SSF52540 2 224 5.44E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS38185 e33c91f3baebe501cb890565ea39711a 313 Gene3D G3DSA:3.40.50.300 1 253 4.1E-62 T 29-03-2018 SMALA_RS38185 e33c91f3baebe501cb890565ea39711a 313 SMART SM00382 26 209 2.1E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS38185 e33c91f3baebe501cb890565ea39711a 313 Pfam PF00005 ABC transporter 17 160 4.7E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS38185 e33c91f3baebe501cb890565ea39711a 313 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 10 302 6.4E-97 T 29-03-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 SMALA_RS41105 175062ef363ed0de9ef22817577316e0 125 Pfam PF12680 SnoaL-like domain 11 109 3.7E-6 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain SMALA_RS41105 175062ef363ed0de9ef22817577316e0 125 Gene3D G3DSA:3.10.450.50 2 119 7.1E-13 T 29-03-2018 SMALA_RS41105 175062ef363ed0de9ef22817577316e0 125 SUPERFAMILY SSF54427 5 117 4.18E-19 T 29-03-2018 IPR032710 NTF2-like domain SMALA_RS07640 5176cd0223a8aa39f770ae755bdfe71d 402 Pfam PF07728 AAA domain (dynein-related subfamily) 173 303 8.6E-17 T 29-03-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 SMALA_RS07640 5176cd0223a8aa39f770ae755bdfe71d 402 Gene3D G3DSA:3.40.50.300 156 308 7.4E-20 T 29-03-2018 SMALA_RS07640 5176cd0223a8aa39f770ae755bdfe71d 402 Gene3D G3DSA:1.10.10.10 30 100 5.6E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS07640 5176cd0223a8aa39f770ae755bdfe71d 402 SUPERFAMILY SSF52540 163 322 1.26E-20 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS07640 5176cd0223a8aa39f770ae755bdfe71d 402 SMART SM00382 170 314 1.2E-6 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS34205 d0f9bc47424a7dd58c6db91b1299aed2 988 SUPERFAMILY SSF55874 565 689 6.55E-13 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS34205 d0f9bc47424a7dd58c6db91b1299aed2 988 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 583 680 7.5E-6 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS34205 d0f9bc47424a7dd58c6db91b1299aed2 988 Gene3D G3DSA:3.30.565.10 466 691 2.9E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS34205 d0f9bc47424a7dd58c6db91b1299aed2 988 Pfam PF08376 Nitrate and nitrite sensing 115 361 6.4E-34 T 29-03-2018 IPR013587 Nitrate/nitrite sensing protein SMALA_RS34205 d0f9bc47424a7dd58c6db91b1299aed2 988 SMART SM00387 579 692 0.0016 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS36385 e3e7a31f48d1424ef4429bddc22358ac 275 Pfam PF00296 Luciferase-like monooxygenase 20 240 2.3E-54 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS36385 e3e7a31f48d1424ef4429bddc22358ac 275 TIGRFAM TIGR03619 F420_Rv2161c: probable F420-dependent oxidoreductase, Rv2161c family 19 251 1.4E-81 T 29-03-2018 IPR019921 Luciferase-like, F420-dependent oxidoreductase, Rv2161c, predicted SMALA_RS36385 e3e7a31f48d1424ef4429bddc22358ac 275 SUPERFAMILY SSF51679 19 263 1.31E-63 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS36385 e3e7a31f48d1424ef4429bddc22358ac 275 Gene3D G3DSA:3.20.20.30 17 244 1.1E-64 T 29-03-2018 SMALA_RS06360 a72d0bd71a4744caaf5e137a8b9e1d9a 279 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMALA_RS06360 a72d0bd71a4744caaf5e137a8b9e1d9a 279 Pfam PF00106 short chain dehydrogenase 8 197 1.1E-48 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS06360 a72d0bd71a4744caaf5e137a8b9e1d9a 279 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 1.8E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS06360 a72d0bd71a4744caaf5e137a8b9e1d9a 279 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 1.8E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS06360 a72d0bd71a4744caaf5e137a8b9e1d9a 279 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 1.8E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS06360 a72d0bd71a4744caaf5e137a8b9e1d9a 279 Gene3D G3DSA:3.40.50.720 1 264 9.7E-54 T 29-03-2018 SMALA_RS06360 a72d0bd71a4744caaf5e137a8b9e1d9a 279 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 185 0.0073 T 29-03-2018 SMALA_RS06360 a72d0bd71a4744caaf5e137a8b9e1d9a 279 PIRSF PIRSF000126 1 266 2.6E-74 T 29-03-2018 SMALA_RS06360 a72d0bd71a4744caaf5e137a8b9e1d9a 279 SUPERFAMILY SSF51735 2 251 5.03E-61 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS06360 a72d0bd71a4744caaf5e137a8b9e1d9a 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 1.8E-23 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS06360 a72d0bd71a4744caaf5e137a8b9e1d9a 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 1.8E-23 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS06360 a72d0bd71a4744caaf5e137a8b9e1d9a 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.8E-23 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS06360 a72d0bd71a4744caaf5e137a8b9e1d9a 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 1.8E-23 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS06360 a72d0bd71a4744caaf5e137a8b9e1d9a 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 1.8E-23 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS39280 d9fd4d5d357a017d80a316d8a7a9f8f5 936 Pfam PF13191 AAA ATPase domain 3 167 2.4E-12 T 29-03-2018 SMALA_RS39280 d9fd4d5d357a017d80a316d8a7a9f8f5 936 Gene3D G3DSA:1.10.10.10 885 930 1.1E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS39280 d9fd4d5d357a017d80a316d8a7a9f8f5 936 Gene3D G3DSA:1.25.40.10 659 884 5.2E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS39280 d9fd4d5d357a017d80a316d8a7a9f8f5 936 SMART SM00421 871 928 8.7E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS39280 d9fd4d5d357a017d80a316d8a7a9f8f5 936 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 874 888 6.7E-6 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS39280 d9fd4d5d357a017d80a316d8a7a9f8f5 936 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 888 904 6.7E-6 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS39280 d9fd4d5d357a017d80a316d8a7a9f8f5 936 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 904 916 6.7E-6 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS39280 d9fd4d5d357a017d80a316d8a7a9f8f5 936 SUPERFAMILY SSF52540 15 81 7.2E-9 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS39280 d9fd4d5d357a017d80a316d8a7a9f8f5 936 SUPERFAMILY SSF52540 129 244 7.2E-9 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS39280 d9fd4d5d357a017d80a316d8a7a9f8f5 936 Gene3D G3DSA:1.25.40.10 354 658 7.5E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS39280 d9fd4d5d357a017d80a316d8a7a9f8f5 936 Pfam PF00196 Bacterial regulatory proteins, luxR family 873 923 1.1E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS39280 d9fd4d5d357a017d80a316d8a7a9f8f5 936 SUPERFAMILY SSF46894 867 924 6.12E-12 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS39280 d9fd4d5d357a017d80a316d8a7a9f8f5 936 Gene3D G3DSA:3.40.50.300 3 197 5.1E-10 T 29-03-2018 SMALA_RS19975 0340bec7d96413e633f504c3d2bc0a10 349 Pfam PF02779 Transketolase, pyrimidine binding domain 14 187 8.6E-45 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain SMALA_RS19975 0340bec7d96413e633f504c3d2bc0a10 349 SMART SM00861 14 189 2.5E-66 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain SMALA_RS19975 0340bec7d96413e633f504c3d2bc0a10 349 Pfam PF02780 Transketolase, C-terminal domain 220 330 1.5E-34 T 29-03-2018 IPR033248 Transketolase, C-terminal domain SMALA_RS19975 0340bec7d96413e633f504c3d2bc0a10 349 Gene3D G3DSA:3.40.50.920 206 338 2.1E-29 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMALA_RS19975 0340bec7d96413e633f504c3d2bc0a10 349 Gene3D G3DSA:3.40.50.970 10 205 4.4E-61 T 29-03-2018 SMALA_RS19975 0340bec7d96413e633f504c3d2bc0a10 349 SUPERFAMILY SSF52518 13 196 8.25E-66 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold SMALA_RS19975 0340bec7d96413e633f504c3d2bc0a10 349 SUPERFAMILY SSF52922 201 336 4.45E-35 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMALA_RS18810 0372e409886ac192ee66f221b789f336 449 Pfam PF01553 Acyltransferase 93 213 1.7E-16 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SMALA_RS18810 0372e409886ac192ee66f221b789f336 449 Gene3D G3DSA:3.40.1130.10 63 271 3.1E-30 T 29-03-2018 SMALA_RS18810 0372e409886ac192ee66f221b789f336 449 SMART SM00563 100 216 2.8E-15 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SMALA_RS18810 0372e409886ac192ee66f221b789f336 449 SUPERFAMILY SSF69593 69 243 6.93E-29 T 29-03-2018 SMALA_RS36640 50c14f658255f9f19c668b0826c07091 486 Pfam PF00171 Aldehyde dehydrogenase family 20 475 1.1E-153 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS36640 50c14f658255f9f19c668b0826c07091 486 Gene3D G3DSA:3.40.605.10 1 270 2.9E-83 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS36640 50c14f658255f9f19c668b0826c07091 486 Gene3D G3DSA:3.40.309.10 271 459 3.7E-65 T 29-03-2018 SMALA_RS36640 50c14f658255f9f19c668b0826c07091 486 SUPERFAMILY SSF53720 2 476 4.19E-148 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMALA_RS36640 50c14f658255f9f19c668b0826c07091 486 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 252 259 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 SMALA_RS28075 0438c426a3461ca1fa4811ff7a07d0f0 699 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 577 664 1.6E-6 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS28075 0438c426a3461ca1fa4811ff7a07d0f0 699 SUPERFAMILY SSF55874 551 664 2.1E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS28075 0438c426a3461ca1fa4811ff7a07d0f0 699 Gene3D G3DSA:3.30.450.40 340 402 0.036 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS28075 0438c426a3461ca1fa4811ff7a07d0f0 699 Pfam PF07730 Histidine kinase 472 538 1.3E-11 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMALA_RS28075 0438c426a3461ca1fa4811ff7a07d0f0 699 Gene3D G3DSA:3.30.450.40 403 478 1.5E-6 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS28075 0438c426a3461ca1fa4811ff7a07d0f0 699 SMART SM00387 576 666 4.1E-10 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS28075 0438c426a3461ca1fa4811ff7a07d0f0 699 Gene3D G3DSA:3.30.565.10 531 672 5.8E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS41485 3d3749178bf321c557082db67424fa56 773 SUPERFAMILY SSF48264 13 406 3.67E-80 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS41485 3d3749178bf321c557082db67424fa56 773 Pfam PF16864 Dimerisation domain 443 519 7.6E-7 T 29-03-2018 IPR031725 Acetylserotonin O-methyltransferase, dimerisation domain SMALA_RS41485 3d3749178bf321c557082db67424fa56 773 Pfam PF00067 Cytochrome P450 280 371 1.2E-16 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS41485 3d3749178bf321c557082db67424fa56 773 Gene3D G3DSA:1.10.630.10 2 407 2.6E-62 T 29-03-2018 SMALA_RS41485 3d3749178bf321c557082db67424fa56 773 Gene3D G3DSA:1.10.10.10 432 525 1.8E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS41485 3d3749178bf321c557082db67424fa56 773 Gene3D G3DSA:3.40.50.150 526 770 4.6E-37 T 29-03-2018 SMALA_RS41485 3d3749178bf321c557082db67424fa56 773 PRINTS PR00359 B-class P450 signature 298 325 8.3E-52 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS41485 3d3749178bf321c557082db67424fa56 773 PRINTS PR00359 B-class P450 signature 139 155 8.3E-52 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS41485 3d3749178bf321c557082db67424fa56 773 PRINTS PR00359 B-class P450 signature 156 171 8.3E-52 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS41485 3d3749178bf321c557082db67424fa56 773 PRINTS PR00359 B-class P450 signature 281 292 8.3E-52 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS41485 3d3749178bf321c557082db67424fa56 773 PRINTS PR00359 B-class P450 signature 356 367 8.3E-52 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS41485 3d3749178bf321c557082db67424fa56 773 PRINTS PR00359 B-class P450 signature 326 341 8.3E-52 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS41485 3d3749178bf321c557082db67424fa56 773 PRINTS PR00359 B-class P450 signature 94 105 8.3E-52 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS41485 3d3749178bf321c557082db67424fa56 773 PRINTS PR00359 B-class P450 signature 347 356 8.3E-52 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS41485 3d3749178bf321c557082db67424fa56 773 PRINTS PR00359 B-class P450 signature 201 223 8.3E-52 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS41485 3d3749178bf321c557082db67424fa56 773 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 349 358 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMALA_RS41485 3d3749178bf321c557082db67424fa56 773 PRINTS PR00385 P450 superfamily signature 347 356 2.8E-6 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS41485 3d3749178bf321c557082db67424fa56 773 PRINTS PR00385 P450 superfamily signature 356 367 2.8E-6 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS41485 3d3749178bf321c557082db67424fa56 773 PRINTS PR00385 P450 superfamily signature 246 263 2.8E-6 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS41485 3d3749178bf321c557082db67424fa56 773 PRINTS PR00385 P450 superfamily signature 281 292 2.8E-6 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS41485 3d3749178bf321c557082db67424fa56 773 SUPERFAMILY SSF53335 529 765 1.09E-39 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS41485 3d3749178bf321c557082db67424fa56 773 SUPERFAMILY SSF46785 440 513 3.17E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS41485 3d3749178bf321c557082db67424fa56 773 Pfam PF00891 O-methyltransferase 540 754 3.0E-32 T 29-03-2018 IPR001077 O-methyltransferase, family 2 GO:0008171 SMALA_RS26570 1106d8e5575372ccc3274630013edaee 246 Gene3D G3DSA:1.10.10.10 138 246 5.6E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS26570 1106d8e5575372ccc3274630013edaee 246 Gene3D G3DSA:3.40.50.2300 1 137 3.5E-38 T 29-03-2018 SMALA_RS26570 1106d8e5575372ccc3274630013edaee 246 SUPERFAMILY SSF52172 14 139 1.01E-41 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS26570 1106d8e5575372ccc3274630013edaee 246 Pfam PF00072 Response regulator receiver domain 22 130 3.9E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS26570 1106d8e5575372ccc3274630013edaee 246 SUPERFAMILY SSF46894 147 242 5.39E-27 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS26570 1106d8e5575372ccc3274630013edaee 246 Pfam PF00486 Transcriptional regulatory protein, C terminal 170 241 1.0E-23 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS26570 1106d8e5575372ccc3274630013edaee 246 SMART SM00448 20 130 4.8E-42 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS26570 1106d8e5575372ccc3274630013edaee 246 SMART SM00862 170 241 1.7E-25 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS31185 af789137f3ce14bf0ff98ec263be8090 348 PIRSF PIRSF026166 17 344 2.3E-110 T 29-03-2018 IPR016833 Putative sodium bile acid cotransporter SMALA_RS31185 af789137f3ce14bf0ff98ec263be8090 348 Pfam PF13593 SBF-like CPA transporter family (DUF4137) 23 328 4.3E-83 T 29-03-2018 IPR016833 Putative sodium bile acid cotransporter SMALA_RS35285 5a3b8412d07be5b6b28f99f02a82930a 348 Gene3D G3DSA:3.30.530.20 119 261 1.3E-14 T 29-03-2018 IPR023393 START-like domain SMALA_RS35285 5a3b8412d07be5b6b28f99f02a82930a 348 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 127 255 1.5E-9 T 29-03-2018 IPR005031 Coenzyme Q-binding protein COQ10, START domain Reactome: R-HSA-611105 SMALA_RS35285 5a3b8412d07be5b6b28f99f02a82930a 348 SUPERFAMILY SSF55961 119 251 4.0E-18 T 29-03-2018 SMALA_RS41885 0cc980153c9db7392d3a0722bfd983b7 282 Gene3D G3DSA:1.10.260.40 2 97 1.2E-15 T 29-03-2018 SMALA_RS41885 0cc980153c9db7392d3a0722bfd983b7 282 Pfam PF13560 Helix-turn-helix domain 3 82 1.5E-18 T 29-03-2018 SMALA_RS41885 0cc980153c9db7392d3a0722bfd983b7 282 SUPERFAMILY SSF47413 26 76 3.56E-9 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS41885 0cc980153c9db7392d3a0722bfd983b7 282 SMART SM00530 7 79 4.4E-9 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS29600 679a22c6e7fc4441526e0f77f3231a12 384 Gene3D G3DSA:3.20.20.330 2 384 2.0E-90 T 29-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 SMALA_RS29600 679a22c6e7fc4441526e0f77f3231a12 384 SUPERFAMILY SSF82282 186 383 6.08E-67 T 29-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 SMALA_RS29600 679a22c6e7fc4441526e0f77f3231a12 384 SUPERFAMILY SSF82282 7 103 6.08E-67 T 29-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 SMALA_RS29600 679a22c6e7fc4441526e0f77f3231a12 384 Pfam PF02574 Homocysteine S-methyltransferase 17 380 9.3E-69 T 29-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 SMALA_RS33630 501c27545d86d502a28074b4e6382674 425 Gene3D G3DSA:3.40.640.10 16 260 3.0E-36 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS33630 501c27545d86d502a28074b4e6382674 425 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 30 392 5.4E-76 T 29-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase SMALA_RS33630 501c27545d86d502a28074b4e6382674 425 PIRSF PIRSF000390 12 410 1.2E-78 T 29-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase SMALA_RS33630 501c27545d86d502a28074b4e6382674 425 SUPERFAMILY SSF53383 22 392 5.49E-78 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS33630 501c27545d86d502a28074b4e6382674 425 Gene3D G3DSA:3.90.1150.10 261 422 2.2E-22 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS22835 bba8273050dac64fde1714f90ffaac55 366 Gene3D G3DSA:3.30.420.40 5 145 7.1E-36 T 29-03-2018 SMALA_RS22835 bba8273050dac64fde1714f90ffaac55 366 Gene3D G3DSA:3.30.420.40 146 297 7.4E-18 T 29-03-2018 SMALA_RS22835 bba8273050dac64fde1714f90ffaac55 366 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 7 321 1.4E-126 T 29-03-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SMALA_RS22835 bba8273050dac64fde1714f90ffaac55 366 ProSitePatterns PS01016 Glycoprotease family signature. 99 119 - T 29-03-2018 IPR017860 Peptidase M22, conserved site KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618|Reactome: R-HSA-6782315 SMALA_RS22835 bba8273050dac64fde1714f90ffaac55 366 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 8 314 3.4E-99 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SMALA_RS22835 bba8273050dac64fde1714f90ffaac55 366 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 5 340 61.636 T 29-03-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SMALA_RS22835 bba8273050dac64fde1714f90ffaac55 366 SUPERFAMILY SSF53067 6 316 8.2E-37 T 29-03-2018 SMALA_RS22835 bba8273050dac64fde1714f90ffaac55 366 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 134 146 2.9E-51 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SMALA_RS22835 bba8273050dac64fde1714f90ffaac55 366 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 100 119 2.9E-51 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SMALA_RS22835 bba8273050dac64fde1714f90ffaac55 366 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 158 179 2.9E-51 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SMALA_RS22835 bba8273050dac64fde1714f90ffaac55 366 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 8 21 2.9E-51 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SMALA_RS22835 bba8273050dac64fde1714f90ffaac55 366 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 79 99 2.9E-51 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SMALA_RS22835 bba8273050dac64fde1714f90ffaac55 366 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 271 280 2.9E-51 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SMALA_RS22835 bba8273050dac64fde1714f90ffaac55 366 Pfam PF00814 Glycoprotease family 27 314 5.5E-98 T 29-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SMALA_RS14685 9584358d1d8ebb41a67f77e40fced91b 84 SMART SM01294 11 78 0.001 T 29-03-2018 SMALA_RS14685 9584358d1d8ebb41a67f77e40fced91b 84 SUPERFAMILY SSF47336 10 82 2.22E-18 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS14685 9584358d1d8ebb41a67f77e40fced91b 84 Pfam PF00550 Phosphopantetheine attachment site 11 74 1.2E-15 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS14685 9584358d1d8ebb41a67f77e40fced91b 84 Gene3D G3DSA:1.10.1200.10 10 84 2.9E-18 T 29-03-2018 SMALA_RS14685 9584358d1d8ebb41a67f77e40fced91b 84 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 39 78 0.002 T 29-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 SMALA_RS13220 53820d07625dac18b33d9e3d759ba215 428 SUPERFAMILY SSF52540 58 402 7.4E-74 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS13220 53820d07625dac18b33d9e3d759ba215 428 SUPERFAMILY SSF57716 11 46 1.37E-11 T 29-03-2018 SMALA_RS13220 53820d07625dac18b33d9e3d759ba215 428 Pfam PF07724 AAA domain (Cdc48 subfamily) 114 311 2.9E-51 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 SMALA_RS13220 53820d07625dac18b33d9e3d759ba215 428 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 9 411 2.6E-197 T 29-03-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 SMALA_RS13220 53820d07625dac18b33d9e3d759ba215 428 Gene3D G3DSA:3.40.50.300 53 315 1.1E-67 T 29-03-2018 SMALA_RS13220 53820d07625dac18b33d9e3d759ba215 428 SMART SM00382 113 266 1.4E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS13220 53820d07625dac18b33d9e3d759ba215 428 SMART SM00994 10 49 1.1E-23 T 29-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 SMALA_RS13220 53820d07625dac18b33d9e3d759ba215 428 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 2 415 52.553 T 29-03-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 SMALA_RS13220 53820d07625dac18b33d9e3d759ba215 428 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 317 394 1.4E-15 T 29-03-2018 IPR019489 Clp ATPase, C-terminal SMALA_RS13220 53820d07625dac18b33d9e3d759ba215 428 SMART SM01086 317 411 3.2E-30 T 29-03-2018 IPR019489 Clp ATPase, C-terminal SMALA_RS13220 53820d07625dac18b33d9e3d759ba215 428 Pfam PF06689 ClpX C4-type zinc finger 12 48 1.7E-20 T 29-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 SMALA_RS13220 53820d07625dac18b33d9e3d759ba215 428 Gene3D G3DSA:1.10.8.60 317 409 5.3E-31 T 29-03-2018 SMALA_RS33135 b8afb9eeef702759e6c1ee247761c24f 402 SUPERFAMILY SSF52507 2 176 1.11E-58 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 SMALA_RS33135 b8afb9eeef702759e6c1ee247761c24f 402 Gene3D G3DSA:3.40.50.1950 1 182 1.8E-55 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 SMALA_RS33135 b8afb9eeef702759e6c1ee247761c24f 402 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 4 397 3.0E-118 T 29-03-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 SMALA_RS33135 b8afb9eeef702759e6c1ee247761c24f 402 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 187 371 7.1E-70 T 29-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 SMALA_RS33135 b8afb9eeef702759e6c1ee247761c24f 402 Gene3D G3DSA:3.40.50.10300 183 402 7.8E-66 T 29-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 SMALA_RS33135 b8afb9eeef702759e6c1ee247761c24f 402 SUPERFAMILY SSF102645 186 401 1.26E-66 T 29-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 SMALA_RS33135 b8afb9eeef702759e6c1ee247761c24f 402 Pfam PF02441 Flavoprotein 5 174 1.1E-41 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 SMALA_RS02385 b78db3aa652a084415d9df5a5ef075be 320 SUPERFAMILY SSF51735 138 280 8.09E-23 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS02385 b78db3aa652a084415d9df5a5ef075be 320 Gene3D G3DSA:3.90.180.10 1 156 2.0E-42 T 29-03-2018 SMALA_RS02385 b78db3aa652a084415d9df5a5ef075be 320 SUPERFAMILY SSF50129 2 167 1.67E-42 T 29-03-2018 IPR011032 GroES-like SMALA_RS02385 b78db3aa652a084415d9df5a5ef075be 320 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 54 68 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 SMALA_RS02385 b78db3aa652a084415d9df5a5ef075be 320 Gene3D G3DSA:3.40.50.720 157 266 1.5E-17 T 29-03-2018 SMALA_RS02385 b78db3aa652a084415d9df5a5ef075be 320 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 21 127 2.2E-28 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS02385 b78db3aa652a084415d9df5a5ef075be 320 Pfam PF00107 Zinc-binding dehydrogenase 169 277 7.0E-11 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMALA_RS14075 f096dd5a7d7cad5a880c9ebf3160c862 380 Pfam PF05175 Methyltransferase small domain 202 279 9.0E-12 T 29-03-2018 IPR007848 Methyltransferase small domain GO:0008168 SMALA_RS14075 f096dd5a7d7cad5a880c9ebf3160c862 380 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 269 275 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 SMALA_RS14075 f096dd5a7d7cad5a880c9ebf3160c862 380 SUPERFAMILY SSF53335 176 318 6.57E-31 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS14075 f096dd5a7d7cad5a880c9ebf3160c862 380 Gene3D G3DSA:3.40.50.150 31 380 1.2E-26 T 29-03-2018 SMALA_RS26835 5202d7a92c8e0c06b5bf48fe378325b4 304 Gene3D G3DSA:3.30.230.10 9 174 9.7E-34 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SMALA_RS26835 5202d7a92c8e0c06b5bf48fe378325b4 304 PRINTS PR00958 Homoserine kinase signature 254 269 5.5E-34 T 29-03-2018 SMALA_RS26835 5202d7a92c8e0c06b5bf48fe378325b4 304 PRINTS PR00958 Homoserine kinase signature 18 33 5.5E-34 T 29-03-2018 SMALA_RS26835 5202d7a92c8e0c06b5bf48fe378325b4 304 PRINTS PR00958 Homoserine kinase signature 138 151 5.5E-34 T 29-03-2018 SMALA_RS26835 5202d7a92c8e0c06b5bf48fe378325b4 304 PRINTS PR00958 Homoserine kinase signature 101 116 5.5E-34 T 29-03-2018 SMALA_RS26835 5202d7a92c8e0c06b5bf48fe378325b4 304 PRINTS PR00958 Homoserine kinase signature 177 194 5.5E-34 T 29-03-2018 SMALA_RS26835 5202d7a92c8e0c06b5bf48fe378325b4 304 Pfam PF00288 GHMP kinases N terminal domain 88 151 8.4E-12 T 29-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 SMALA_RS26835 5202d7a92c8e0c06b5bf48fe378325b4 304 SUPERFAMILY SSF55060 173 292 9.59E-28 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain SMALA_RS26835 5202d7a92c8e0c06b5bf48fe378325b4 304 TIGRFAM TIGR00191 thrB: homoserine kinase 11 281 1.6E-63 T 29-03-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 SMALA_RS26835 5202d7a92c8e0c06b5bf48fe378325b4 304 PIRSF PIRSF000676 7 300 1.5E-84 T 29-03-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 SMALA_RS26835 5202d7a92c8e0c06b5bf48fe378325b4 304 Gene3D G3DSA:3.30.70.890 175 300 1.3E-24 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain SMALA_RS26835 5202d7a92c8e0c06b5bf48fe378325b4 304 SUPERFAMILY SSF54211 11 156 1.14E-29 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SMALA_RS26835 5202d7a92c8e0c06b5bf48fe378325b4 304 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 94 105 - T 29-03-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 SMALA_RS26835 5202d7a92c8e0c06b5bf48fe378325b4 304 Hamap MF_00384 Homoserine kinase [thrB]. 11 300 29.383 T 29-03-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 SMALA_RS26835 5202d7a92c8e0c06b5bf48fe378325b4 304 Pfam PF08544 GHMP kinases C terminal 222 280 4.1E-6 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain SMALA_RS04120 466bf66ee53af8d730f72a3ce7237cb3 379 Pfam PF13551 Winged helix-turn helix 36 95 1.7E-7 T 29-03-2018 SMALA_RS04120 466bf66ee53af8d730f72a3ce7237cb3 379 Pfam PF13358 DDE superfamily endonuclease 192 339 4.0E-13 T 29-03-2018 SMALA_RS04120 466bf66ee53af8d730f72a3ce7237cb3 379 SUPERFAMILY SSF46689 35 147 1.24E-9 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS04120 466bf66ee53af8d730f72a3ce7237cb3 379 Gene3D G3DSA:3.30.420.10 183 377 3.2E-6 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SMALA_RS30525 95f4925b470d766692fb466a83c89b84 293 SUPERFAMILY SSF55620 137 287 3.67E-57 T 29-03-2018 SMALA_RS30525 95f4925b470d766692fb466a83c89b84 293 PIRSF PIRSF000241 1 290 1.3E-105 T 29-03-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 SMALA_RS30525 95f4925b470d766692fb466a83c89b84 293 Pfam PF01014 Uricase 8 130 5.0E-18 T 29-03-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 SMALA_RS30525 95f4925b470d766692fb466a83c89b84 293 Pfam PF01014 Uricase 141 278 9.0E-32 T 29-03-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 SMALA_RS30525 95f4925b470d766692fb466a83c89b84 293 SUPERFAMILY SSF55620 4 129 1.87E-40 T 29-03-2018 SMALA_RS30525 95f4925b470d766692fb466a83c89b84 293 PRINTS PR00093 Uricase signature 162 174 7.2E-19 T 29-03-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 SMALA_RS30525 95f4925b470d766692fb466a83c89b84 293 PRINTS PR00093 Uricase signature 146 162 7.2E-19 T 29-03-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 SMALA_RS30525 95f4925b470d766692fb466a83c89b84 293 PRINTS PR00093 Uricase signature 85 98 7.2E-19 T 29-03-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 SMALA_RS30525 95f4925b470d766692fb466a83c89b84 293 PRINTS PR00093 Uricase signature 49 63 7.2E-19 T 29-03-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 SMALA_RS30525 95f4925b470d766692fb466a83c89b84 293 PRINTS PR00093 Uricase signature 10 21 7.2E-19 T 29-03-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 SMALA_RS30525 95f4925b470d766692fb466a83c89b84 293 TIGRFAM TIGR03383 urate_oxi: urate oxidase 4 283 5.9E-107 T 29-03-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 SMALA_RS30525 95f4925b470d766692fb466a83c89b84 293 Gene3D G3DSA:3.10.270.10 1 289 1.6E-116 T 29-03-2018 SMALA_RS30525 95f4925b470d766692fb466a83c89b84 293 ProDom PD003367 URICASE OXIDOREDUCTASE URATE OXIDASE METABOLISM PURINE PEROXISOME ACETYLATION II DIRECT 176 283 1.0E-45 T 29-03-2018 SMALA_RS03580 57e54671891fa18f9b66d5abca4c1491 228 TIGRFAM TIGR00370 TIGR00370: sensor histidine kinase inhibitor, KipI family 31 203 8.8E-45 T 29-03-2018 IPR010016 KipI family SMALA_RS03580 57e54671891fa18f9b66d5abca4c1491 228 Gene3D G3DSA:2.40.100.10 81 210 8.5E-52 T 29-03-2018 IPR029000 Cyclophilin-like domain SMALA_RS03580 57e54671891fa18f9b66d5abca4c1491 228 SMART SM00796 3 194 1.6E-79 T 29-03-2018 IPR003833 Carboxyltransferase domain, subdomain C and D SMALA_RS03580 57e54671891fa18f9b66d5abca4c1491 228 SUPERFAMILY SSF50891 83 205 1.9E-40 T 29-03-2018 IPR029000 Cyclophilin-like domain SMALA_RS03580 57e54671891fa18f9b66d5abca4c1491 228 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 3 193 1.3E-60 T 29-03-2018 IPR003833 Carboxyltransferase domain, subdomain C and D SMALA_RS03580 57e54671891fa18f9b66d5abca4c1491 228 Gene3D G3DSA:3.30.1360.40 1 80 1.2E-17 T 29-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 SMALA_RS33420 236801719a5afc2465ba1b40a8cb4ef1 572 SUPERFAMILY SSF56645 30 242 6.28E-39 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMALA_RS33420 236801719a5afc2465ba1b40a8cb4ef1 572 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 235 385 3.2E-18 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMALA_RS33420 236801719a5afc2465ba1b40a8cb4ef1 572 Gene3D G3DSA:2.40.110.10 125 228 2.4E-23 T 29-03-2018 SMALA_RS33420 236801719a5afc2465ba1b40a8cb4ef1 572 Gene3D G3DSA:1.20.140.10 229 395 1.9E-22 T 29-03-2018 SMALA_RS33420 236801719a5afc2465ba1b40a8cb4ef1 572 SUPERFAMILY SSF47203 235 385 7.73E-21 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMALA_RS33420 236801719a5afc2465ba1b40a8cb4ef1 572 Gene3D G3DSA:1.10.540.10 2 124 4.9E-8 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS33420 236801719a5afc2465ba1b40a8cb4ef1 572 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 125 219 2.6E-15 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 SMALA_RS39390 7a3602ff79d95ee08efca6f665c17306 355 Gene3D G3DSA:2.60.120.10 22 186 2.3E-21 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SMALA_RS39390 7a3602ff79d95ee08efca6f665c17306 355 Pfam PF07883 Cupin domain 233 304 3.5E-13 T 29-03-2018 IPR013096 Cupin 2, conserved barrel SMALA_RS39390 7a3602ff79d95ee08efca6f665c17306 355 Pfam PF07883 Cupin domain 71 135 6.3E-16 T 29-03-2018 IPR013096 Cupin 2, conserved barrel SMALA_RS39390 7a3602ff79d95ee08efca6f665c17306 355 SUPERFAMILY SSF51182 51 307 5.86E-47 T 29-03-2018 IPR011051 RmlC-like cupin domain SMALA_RS39390 7a3602ff79d95ee08efca6f665c17306 355 Gene3D G3DSA:2.60.120.10 187 322 6.8E-19 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SMALA_RS19665 7bb3dcbb36650f3e717baaca15bd42ad 109 TIGRFAM TIGR01068 thioredoxin: thioredoxin 9 106 1.4E-36 T 29-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 SMALA_RS19665 7bb3dcbb36650f3e717baaca15bd42ad 109 ProSitePatterns PS00194 Thioredoxin family active site. 25 43 - T 29-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 SMALA_RS19665 7bb3dcbb36650f3e717baaca15bd42ad 109 PIRSF PIRSF000077 2 108 4.0E-42 T 29-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 SMALA_RS19665 7bb3dcbb36650f3e717baaca15bd42ad 109 Gene3D G3DSA:3.40.30.10 2 107 1.2E-34 T 29-03-2018 SMALA_RS19665 7bb3dcbb36650f3e717baaca15bd42ad 109 SUPERFAMILY SSF52833 5 107 2.7E-37 T 29-03-2018 IPR012336 Thioredoxin-like fold SMALA_RS19665 7bb3dcbb36650f3e717baaca15bd42ad 109 Pfam PF00085 Thioredoxin 6 104 7.6E-33 T 29-03-2018 IPR013766 Thioredoxin domain GO:0045454 SMALA_RS19665 7bb3dcbb36650f3e717baaca15bd42ad 109 PRINTS PR00421 Thioredoxin family signature 72 83 1.0E-7 T 29-03-2018 SMALA_RS19665 7bb3dcbb36650f3e717baaca15bd42ad 109 PRINTS PR00421 Thioredoxin family signature 32 41 1.0E-7 T 29-03-2018 SMALA_RS19665 7bb3dcbb36650f3e717baaca15bd42ad 109 PRINTS PR00421 Thioredoxin family signature 24 32 1.0E-7 T 29-03-2018 SMALA_RS38570 fb8cfdf3c931da9009a8c0cb824c4a33 332 TIGRFAM TIGR01230 agmatinase: agmatinase 39 314 1.2E-70 T 29-03-2018 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|Reactome: R-HSA-351143 SMALA_RS38570 fb8cfdf3c931da9009a8c0cb824c4a33 332 PIRSF PIRSF036979 24 320 3.3E-107 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 SMALA_RS38570 fb8cfdf3c931da9009a8c0cb824c4a33 332 ProSitePatterns PS01053 Arginase family signature. 244 265 - T 29-03-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 SMALA_RS38570 fb8cfdf3c931da9009a8c0cb824c4a33 332 Gene3D G3DSA:3.40.800.10 11 322 1.1E-106 T 29-03-2018 SMALA_RS38570 fb8cfdf3c931da9009a8c0cb824c4a33 332 Pfam PF00491 Arginase family 41 312 2.3E-90 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 SMALA_RS38570 fb8cfdf3c931da9009a8c0cb824c4a33 332 SUPERFAMILY SSF52768 22 316 1.98E-97 T 29-03-2018 SMALA_RS38570 fb8cfdf3c931da9009a8c0cb824c4a33 332 PRINTS PR00116 Arginase signature 128 143 1.1E-14 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 SMALA_RS38570 fb8cfdf3c931da9009a8c0cb824c4a33 332 PRINTS PR00116 Arginase signature 241 270 1.1E-14 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 SMALA_RS06365 940dd9ba7fcba5f764762b82858d8b20 219 Gene3D G3DSA:3.40.50.2300 69 174 4.4E-7 T 29-03-2018 SMALA_RS16440 466b26b66301c53e3b8b42defdc89be2 260 Pfam PF04542 Sigma-70 region 2 98 161 1.2E-11 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS16440 466b26b66301c53e3b8b42defdc89be2 260 Gene3D G3DSA:1.10.10.10 159 243 1.3E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS16440 466b26b66301c53e3b8b42defdc89be2 260 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 87 242 1.8E-61 T 29-03-2018 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 SMALA_RS16440 466b26b66301c53e3b8b42defdc89be2 260 Gene3D G3DSA:1.10.1740.10 79 158 6.9E-15 T 29-03-2018 SMALA_RS16440 466b26b66301c53e3b8b42defdc89be2 260 Pfam PF08281 Sigma-70, region 4 188 239 1.4E-14 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS16440 466b26b66301c53e3b8b42defdc89be2 260 SUPERFAMILY SSF88659 180 241 1.59E-16 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS16440 466b26b66301c53e3b8b42defdc89be2 260 SUPERFAMILY SSF88946 88 173 1.02E-14 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS16440 466b26b66301c53e3b8b42defdc89be2 260 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 97 241 6.3E-24 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS40580 a1926b91a1683f95a199fbc79735eea2 263 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 77 260 4.7E-29 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS40580 a1926b91a1683f95a199fbc79735eea2 263 SUPERFAMILY SSF161098 54 241 1.44E-25 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS40580 a1926b91a1683f95a199fbc79735eea2 263 Gene3D G3DSA:1.10.3720.10 1 261 1.8E-39 T 29-03-2018 SMALA_RS41460 76d682bfbbd3e2061dc4d07a3f260c78 416 Gene3D G3DSA:3.50.50.60 6 357 9.3E-42 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS41460 76d682bfbbd3e2061dc4d07a3f260c78 416 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 288 303 6.8E-16 T 29-03-2018 SMALA_RS41460 76d682bfbbd3e2061dc4d07a3f260c78 416 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 160 175 6.8E-16 T 29-03-2018 SMALA_RS41460 76d682bfbbd3e2061dc4d07a3f260c78 416 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 9 31 6.8E-16 T 29-03-2018 SMALA_RS41460 76d682bfbbd3e2061dc4d07a3f260c78 416 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 303 319 6.8E-16 T 29-03-2018 SMALA_RS41460 76d682bfbbd3e2061dc4d07a3f260c78 416 Pfam PF01494 FAD binding domain 8 346 2.0E-24 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 SMALA_RS41460 76d682bfbbd3e2061dc4d07a3f260c78 416 SUPERFAMILY SSF51905 8 181 1.78E-48 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS41460 76d682bfbbd3e2061dc4d07a3f260c78 416 SUPERFAMILY SSF51905 275 373 1.78E-48 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS06755 cdfc5a24183eaea6f1eeffebeba066a2 662 SUPERFAMILY SSF52540 73 233 4.89E-5 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS06755 cdfc5a24183eaea6f1eeffebeba066a2 662 Gene3D G3DSA:3.40.50.300 69 515 1.3E-4 T 29-03-2018 SMALA_RS19680 deaf822c4d252308cd6e54f172034818 362 Pfam PF13614 AAA domain 80 256 4.3E-57 T 29-03-2018 IPR025669 AAA domain SMALA_RS19680 deaf822c4d252308cd6e54f172034818 362 Gene3D G3DSA:3.40.50.300 79 344 8.9E-61 T 29-03-2018 SMALA_RS19680 deaf822c4d252308cd6e54f172034818 362 SUPERFAMILY SSF52540 80 329 2.34E-64 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS17875 bbfbf00f098b99ce1c4197c21a17c614 544 SMART SM00880 44 530 0.003 T 29-03-2018 IPR007899 CHAD domain SMALA_RS17875 bbfbf00f098b99ce1c4197c21a17c614 544 Pfam PF05235 CHAD domain 295 449 1.5E-10 T 29-03-2018 IPR007899 CHAD domain SMALA_RS17875 bbfbf00f098b99ce1c4197c21a17c614 544 Pfam PF05235 CHAD domain 53 168 2.9E-8 T 29-03-2018 IPR007899 CHAD domain SMALA_RS24660 9700d226a06c71d69e60f7082c19ca96 156 Pfam PF02643 Uncharacterized ACR, COG1430 50 142 1.6E-13 T 29-03-2018 IPR003795 Protein of unknown function DUF192 SMALA_RS24750 c933c91c1827dcfc91014f269e98e75e 318 Gene3D G3DSA:1.10.10.10 6 99 1.6E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS24750 c933c91c1827dcfc91014f269e98e75e 318 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 17 75 9.8E-19 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS24750 c933c91c1827dcfc91014f269e98e75e 318 Gene3D G3DSA:3.40.190.10 101 189 5.6E-22 T 29-03-2018 SMALA_RS24750 c933c91c1827dcfc91014f269e98e75e 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 52 2.1E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS24750 c933c91c1827dcfc91014f269e98e75e 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 52 63 2.1E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS24750 c933c91c1827dcfc91014f269e98e75e 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 42 2.1E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS24750 c933c91c1827dcfc91014f269e98e75e 318 SUPERFAMILY SSF53850 102 314 1.18E-39 T 29-03-2018 SMALA_RS24750 c933c91c1827dcfc91014f269e98e75e 318 Pfam PF03466 LysR substrate binding domain 101 309 3.2E-45 T 29-03-2018 IPR005119 LysR, substrate-binding SMALA_RS24750 c933c91c1827dcfc91014f269e98e75e 318 Gene3D G3DSA:3.40.190.10 190 283 4.2E-24 T 29-03-2018 SMALA_RS24750 c933c91c1827dcfc91014f269e98e75e 318 SUPERFAMILY SSF46785 12 123 1.36E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS22830 c8aa293bef67820f1c3cfdaaa7285218 201 SUPERFAMILY SSF55729 4 143 7.67E-28 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS22830 c8aa293bef67820f1c3cfdaaa7285218 201 Pfam PF00583 Acetyltransferase (GNAT) family 8 121 1.3E-16 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SMALA_RS22830 c8aa293bef67820f1c3cfdaaa7285218 201 Gene3D G3DSA:3.40.630.30 2 172 7.2E-29 T 29-03-2018 SMALA_RS22830 c8aa293bef67820f1c3cfdaaa7285218 201 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 5 141 8.5E-32 T 29-03-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 SMALA_RS15890 e55dae37a36e6cf6d06c6792ae89a761 482 Pfam PF00881 Nitroreductase family 294 462 2.2E-28 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 SMALA_RS15890 e55dae37a36e6cf6d06c6792ae89a761 482 Pfam PF01996 F420-0:Gamma-glutamyl ligase 15 75 2.1E-9 T 29-03-2018 IPR002847 Coenzyme F420:L-glutamate ligase-like domain KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 SMALA_RS15890 e55dae37a36e6cf6d06c6792ae89a761 482 Pfam PF01996 F420-0:Gamma-glutamyl ligase 85 211 1.7E-33 T 29-03-2018 IPR002847 Coenzyme F420:L-glutamate ligase-like domain KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 SMALA_RS15890 e55dae37a36e6cf6d06c6792ae89a761 482 TIGRFAM TIGR03553 F420_FbiB_CTERM: F420 biosynthesis protein FbiB, C-terminal domain 289 482 8.9E-95 T 29-03-2018 IPR019943 Coenzyme F420 biosynthesis protein FbiB, C-terminal GO:0016881 KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 SMALA_RS15890 e55dae37a36e6cf6d06c6792ae89a761 482 Gene3D G3DSA:3.90.1660.10 45 125 5.3E-31 T 29-03-2018 SMALA_RS15890 e55dae37a36e6cf6d06c6792ae89a761 482 Gene3D G3DSA:3.30.1330.100 126 217 9.0E-25 T 29-03-2018 SMALA_RS15890 e55dae37a36e6cf6d06c6792ae89a761 482 Hamap MF_01259 Coenzyme F420:L-glutamate ligase [fbiB]. 12 482 50.133 T 29-03-2018 IPR023661 Coenzyme F420:L-glutamate ligase, bacteria GO:0043773|GO:0046872|GO:0051188 KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 SMALA_RS15890 e55dae37a36e6cf6d06c6792ae89a761 482 SUPERFAMILY SSF55469 287 480 4.97E-38 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMALA_RS15890 e55dae37a36e6cf6d06c6792ae89a761 482 TIGRFAM TIGR01916 F420_cofE: coenzyme F420-0:L-glutamate ligase 8 215 1.0E-72 T 29-03-2018 IPR008225 Coenzyme F420:L-glutamate ligase GO:0043773|GO:0046872|GO:0051188 KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 SMALA_RS15890 e55dae37a36e6cf6d06c6792ae89a761 482 SUPERFAMILY SSF144010 9 215 1.83E-64 T 29-03-2018 SMALA_RS15890 e55dae37a36e6cf6d06c6792ae89a761 482 Gene3D G3DSA:3.40.109.10 285 480 1.8E-35 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMALA_RS14020 a965bd656b43274691b61a2d567ff8e4 320 Gene3D G3DSA:1.10.3720.10 78 310 1.4E-38 T 29-03-2018 SMALA_RS14020 a965bd656b43274691b61a2d567ff8e4 320 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 83 299 3.2E-18 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS14020 a965bd656b43274691b61a2d567ff8e4 320 SUPERFAMILY SSF161098 71 298 2.35E-50 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS14020 a965bd656b43274691b61a2d567ff8e4 320 Gene3D G3DSA:1.20.58.370 17 61 2.6E-7 T 29-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain SMALA_RS14020 a965bd656b43274691b61a2d567ff8e4 320 SUPERFAMILY SSF160964 29 87 3.27E-6 T 29-03-2018 SMALA_RS29565 7f5d7cd11fe2256c92906b10ffb084f1 255 Gene3D G3DSA:3.40.50.10320 1 253 2.6E-34 T 29-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 SMALA_RS29565 7f5d7cd11fe2256c92906b10ffb084f1 255 SUPERFAMILY SSF102588 3 230 8.5E-34 T 29-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 SMALA_RS29565 7f5d7cd11fe2256c92906b10ffb084f1 255 Pfam PF02585 GlcNAc-PI de-N-acetylase 6 162 1.5E-17 T 29-03-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 SMALA_RS26975 f046045b0162de34e13e326fd559b79f 107 Pfam PF13466 STAS domain 10 89 1.1E-15 T 29-03-2018 IPR002645 STAS domain SMALA_RS26975 f046045b0162de34e13e326fd559b79f 107 Gene3D G3DSA:3.30.750.24 4 96 1.7E-13 T 29-03-2018 IPR002645 STAS domain SMALA_RS26975 f046045b0162de34e13e326fd559b79f 107 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 2 98 9.6E-17 T 29-03-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 SMALA_RS26975 f046045b0162de34e13e326fd559b79f 107 SUPERFAMILY SSF52091 2 100 1.47E-21 T 29-03-2018 IPR002645 STAS domain SMALA_RS17430 f27611d7bd44685ec6f3ef28b6dc37fa 242 SUPERFAMILY SSF110395 5 236 1.96E-43 T 29-03-2018 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 Reactome: R-HSA-936837 SMALA_RS17430 f27611d7bd44685ec6f3ef28b6dc37fa 242 Gene3D G3DSA:3.20.20.380 5 239 1.9E-57 T 29-03-2018 SMALA_RS17430 f27611d7bd44685ec6f3ef28b6dc37fa 242 Pfam PF03932 CutC family 5 203 1.3E-23 T 29-03-2018 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 Reactome: R-HSA-936837 SMALA_RS25200 69e3398c8cf8217525c5cb70939f63a3 253 Gene3D G3DSA:1.10.1660.10 1 58 6.3E-17 T 29-03-2018 SMALA_RS25200 69e3398c8cf8217525c5cb70939f63a3 253 Gene3D G3DSA:1.10.1660.10 59 128 4.6E-8 T 29-03-2018 SMALA_RS25200 69e3398c8cf8217525c5cb70939f63a3 253 SMART SM00422 3 72 3.3E-11 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS25200 69e3398c8cf8217525c5cb70939f63a3 253 SUPERFAMILY SSF46955 4 106 2.93E-21 T 29-03-2018 IPR009061 Putative DNA-binding domain SMALA_RS25200 69e3398c8cf8217525c5cb70939f63a3 253 Pfam PF13411 MerR HTH family regulatory protein 4 70 4.0E-11 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS40150 0025f459223cde3d2fb4327c961ab54d 374 Pfam PF09084 NMT1/THI5 like 109 283 4.8E-17 T 29-03-2018 IPR015168 SsuA/THI5-like SMALA_RS40150 0025f459223cde3d2fb4327c961ab54d 374 SMART SM00062 67 283 0.0067 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SMALA_RS40150 0025f459223cde3d2fb4327c961ab54d 374 Gene3D G3DSA:3.40.190.10 179 364 2.2E-25 T 29-03-2018 SMALA_RS40150 0025f459223cde3d2fb4327c961ab54d 374 Gene3D G3DSA:3.40.190.10 87 178 2.7E-4 T 29-03-2018 SMALA_RS40150 0025f459223cde3d2fb4327c961ab54d 374 SUPERFAMILY SSF53850 61 289 1.33E-36 T 29-03-2018 SMALA_RS08795 226541df5d17a25abb4edad8689fa928 280 SUPERFAMILY SSF48452 22 114 9.32E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS08795 226541df5d17a25abb4edad8689fa928 280 SUPERFAMILY SSF48452 144 183 9.32E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS08795 226541df5d17a25abb4edad8689fa928 280 Gene3D G3DSA:1.25.40.10 8 188 1.3E-14 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS08795 226541df5d17a25abb4edad8689fa928 280 Pfam PF14559 Tetratricopeptide repeat 126 184 5.7E-6 T 29-03-2018 SMALA_RS41780 5bc7236c3f76674c81892f0b5f65a137 306 Gene3D G3DSA:3.90.180.10 1 139 2.3E-34 T 29-03-2018 SMALA_RS41780 5bc7236c3f76674c81892f0b5f65a137 306 SMART SM00829 12 301 3.6E-22 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS41780 5bc7236c3f76674c81892f0b5f65a137 306 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 146 167 - T 29-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 SMALA_RS41780 5bc7236c3f76674c81892f0b5f65a137 306 Pfam PF00107 Zinc-binding dehydrogenase 157 238 2.9E-14 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMALA_RS41780 5bc7236c3f76674c81892f0b5f65a137 306 SUPERFAMILY SSF50129 12 151 2.2E-30 T 29-03-2018 IPR011032 GroES-like SMALA_RS41780 5bc7236c3f76674c81892f0b5f65a137 306 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 142 3.8E-8 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS41780 5bc7236c3f76674c81892f0b5f65a137 306 Gene3D G3DSA:3.40.50.720 140 273 1.2E-27 T 29-03-2018 SMALA_RS41780 5bc7236c3f76674c81892f0b5f65a137 306 SUPERFAMILY SSF51735 118 237 1.32E-34 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS20050 6110e95569b43d18106971e27270e0be 475 Pfam PF00364 Biotin-requiring enzyme 10 80 9.3E-23 T 29-03-2018 IPR000089 Biotin/lipoyl attachment SMALA_RS20050 6110e95569b43d18106971e27270e0be 475 Gene3D G3DSA:3.90.1170.30 70 109 0.18 T 29-03-2018 SMALA_RS20050 6110e95569b43d18106971e27270e0be 475 Pfam PF02817 e3 binding domain 185 219 1.5E-12 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 SMALA_RS20050 6110e95569b43d18106971e27270e0be 475 SUPERFAMILY SSF51230 8 100 1.31E-26 T 29-03-2018 IPR011053 Single hybrid motif SMALA_RS20050 6110e95569b43d18106971e27270e0be 475 Gene3D G3DSA:3.30.559.10 231 475 1.2E-81 T 29-03-2018 SMALA_RS20050 6110e95569b43d18106971e27270e0be 475 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 33 62 - T 29-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 SMALA_RS20050 6110e95569b43d18106971e27270e0be 475 Gene3D G3DSA:4.10.320.10 181 230 5.8E-18 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 SMALA_RS20050 6110e95569b43d18106971e27270e0be 475 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 244 472 8.8E-78 T 29-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 SMALA_RS20050 6110e95569b43d18106971e27270e0be 475 SUPERFAMILY SSF52777 234 472 8.45E-78 T 29-03-2018 SMALA_RS20050 6110e95569b43d18106971e27270e0be 475 SUPERFAMILY SSF47005 182 223 4.84E-10 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 SMALA_RS20050 6110e95569b43d18106971e27270e0be 475 Gene3D G3DSA:2.40.50.100 11 69 7.6E-19 T 29-03-2018 SMALA_RS22990 6aa81666c0d1a5fc65672292e787e59b 568 Pfam PF01266 FAD dependent oxidoreductase 24 377 5.7E-51 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 SMALA_RS22990 6aa81666c0d1a5fc65672292e787e59b 568 Gene3D G3DSA:3.40.50.720 21 77 3.5E-5 T 29-03-2018 SMALA_RS22990 6aa81666c0d1a5fc65672292e787e59b 568 ProSitePatterns PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1. 28 45 - T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 SMALA_RS22990 6aa81666c0d1a5fc65672292e787e59b 568 ProSitePatterns PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. 376 386 - T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 SMALA_RS22990 6aa81666c0d1a5fc65672292e787e59b 568 SUPERFAMILY SSF51905 290 351 1.12E-35 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS22990 6aa81666c0d1a5fc65672292e787e59b 568 SUPERFAMILY SSF51905 24 253 1.12E-35 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS22990 6aa81666c0d1a5fc65672292e787e59b 568 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 404 528 1.1E-34 T 29-03-2018 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 SMALA_RS22990 6aa81666c0d1a5fc65672292e787e59b 568 Gene3D G3DSA:3.30.9.10 102 212 2.2E-18 T 29-03-2018 SMALA_RS22990 6aa81666c0d1a5fc65672292e787e59b 568 Gene3D G3DSA:3.30.9.10 213 348 2.7E-42 T 29-03-2018 SMALA_RS22990 6aa81666c0d1a5fc65672292e787e59b 568 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 36 46 8.0E-32 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 SMALA_RS22990 6aa81666c0d1a5fc65672292e787e59b 568 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 341 347 8.0E-32 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 SMALA_RS22990 6aa81666c0d1a5fc65672292e787e59b 568 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 52 64 8.0E-32 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 SMALA_RS22990 6aa81666c0d1a5fc65672292e787e59b 568 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 23 35 8.0E-32 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 SMALA_RS22990 6aa81666c0d1a5fc65672292e787e59b 568 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 98 110 8.0E-32 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 SMALA_RS22990 6aa81666c0d1a5fc65672292e787e59b 568 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 371 383 8.0E-32 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 SMALA_RS42650 91f48ee63f78a7c0751ba1539edb2bdb 214 Gene3D G3DSA:1.10.357.10 85 214 1.9E-15 T 29-03-2018 SMALA_RS42650 91f48ee63f78a7c0751ba1539edb2bdb 214 SUPERFAMILY SSF46689 21 103 2.33E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS42650 91f48ee63f78a7c0751ba1539edb2bdb 214 SUPERFAMILY SSF48498 100 198 5.93E-8 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS42650 91f48ee63f78a7c0751ba1539edb2bdb 214 Gene3D G3DSA:1.10.260.40 57 84 9.9E-10 T 29-03-2018 SMALA_RS42650 91f48ee63f78a7c0751ba1539edb2bdb 214 Pfam PF00440 Bacterial regulatory proteins, tetR family 36 81 5.6E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS42650 91f48ee63f78a7c0751ba1539edb2bdb 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 49 1.1E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS42650 91f48ee63f78a7c0751ba1539edb2bdb 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 56 79 1.1E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS42650 91f48ee63f78a7c0751ba1539edb2bdb 214 Gene3D G3DSA:1.10.10.60 12 56 6.6E-12 T 29-03-2018 SMALA_RS19525 ba2c61d6dd8f1cf321db9aa467122e2c 151 Gene3D G3DSA:3.40.630.30 1 148 1.2E-27 T 29-03-2018 SMALA_RS19525 ba2c61d6dd8f1cf321db9aa467122e2c 151 SUPERFAMILY SSF55729 1 144 2.36E-29 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS19525 ba2c61d6dd8f1cf321db9aa467122e2c 151 Pfam PF00583 Acetyltransferase (GNAT) family 31 139 8.5E-17 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SMALA_RS12705 44350116d0dcd83de1b310781897628f 328 Pfam PF01297 Zinc-uptake complex component A periplasmic 41 324 1.6E-70 T 29-03-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 SMALA_RS12705 44350116d0dcd83de1b310781897628f 328 Gene3D G3DSA:3.40.50.1980 27 207 1.7E-46 T 29-03-2018 SMALA_RS12705 44350116d0dcd83de1b310781897628f 328 PRINTS PR00691 Adhesin B signature 38 59 6.7E-8 T 29-03-2018 IPR006129 Adhesin B GO:0007155 SMALA_RS12705 44350116d0dcd83de1b310781897628f 328 PRINTS PR00691 Adhesin B signature 262 279 6.7E-8 T 29-03-2018 IPR006129 Adhesin B GO:0007155 SMALA_RS12705 44350116d0dcd83de1b310781897628f 328 PRINTS PR00691 Adhesin B signature 304 322 6.7E-8 T 29-03-2018 IPR006129 Adhesin B GO:0007155 SMALA_RS12705 44350116d0dcd83de1b310781897628f 328 PRINTS PR00691 Adhesin B signature 63 81 6.7E-8 T 29-03-2018 IPR006129 Adhesin B GO:0007155 SMALA_RS12705 44350116d0dcd83de1b310781897628f 328 Gene3D G3DSA:3.40.50.1980 208 326 4.9E-33 T 29-03-2018 SMALA_RS12705 44350116d0dcd83de1b310781897628f 328 SUPERFAMILY SSF53807 37 325 4.12E-72 T 29-03-2018 SMALA_RS12705 44350116d0dcd83de1b310781897628f 328 PRINTS PR00690 Adhesin family signature 69 82 1.9E-5 T 29-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 SMALA_RS12705 44350116d0dcd83de1b310781897628f 328 PRINTS PR00690 Adhesin family signature 38 56 1.9E-5 T 29-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 SMALA_RS12705 44350116d0dcd83de1b310781897628f 328 PRINTS PR00690 Adhesin family signature 266 284 1.9E-5 T 29-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 SMALA_RS22205 9d14ec4220f662e2bae6c3fa555ecea8 411 SUPERFAMILY SSF89392 132 298 7.06E-13 T 29-03-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX SMALA_RS22205 9d14ec4220f662e2bae6c3fa555ecea8 411 Gene3D G3DSA:2.50.20.10 61 300 1.9E-51 T 29-03-2018 SMALA_RS17900 0a67ca4d8f71a517f5dfcb0d42e55a48 391 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 218 360 6.4E-17 T 29-03-2018 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 Reactome: R-HSA-156588 SMALA_RS17900 0a67ca4d8f71a517f5dfcb0d42e55a48 391 TIGRFAM TIGR01426 MGT: glycosyltransferase, MGT family 12 390 1.6E-114 T 29-03-2018 IPR006326 UDP-glycosyltransferase, MGT GO:0016758|GO:0016999 SMALA_RS17900 0a67ca4d8f71a517f5dfcb0d42e55a48 391 Gene3D G3DSA:3.40.50.2000 7 229 1.9E-28 T 29-03-2018 SMALA_RS17900 0a67ca4d8f71a517f5dfcb0d42e55a48 391 ProSitePatterns PS00375 UDP-glycosyltransferases signature. 282 323 - T 29-03-2018 IPR035595 UDP-glycosyltransferase family, conserved site Reactome: R-HSA-156588 SMALA_RS17900 0a67ca4d8f71a517f5dfcb0d42e55a48 391 Gene3D G3DSA:3.40.50.2000 230 375 2.4E-40 T 29-03-2018 SMALA_RS17900 0a67ca4d8f71a517f5dfcb0d42e55a48 391 SUPERFAMILY SSF53756 7 391 3.38E-78 T 29-03-2018 SMALA_RS20190 537065453eb3c91f48b0892b606d8977 366 Gene3D G3DSA:3.60.10.10 141 361 2.7E-22 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMALA_RS20190 537065453eb3c91f48b0892b606d8977 366 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 147 352 4.2E-16 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMALA_RS20190 537065453eb3c91f48b0892b606d8977 366 SUPERFAMILY SSF56219 143 360 2.49E-29 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMALA_RS24190 fc4b4dbd56b2be85856ec790fa91f98f 268 Gene3D G3DSA:3.20.20.150 2 266 1.7E-36 T 29-03-2018 SMALA_RS24190 fc4b4dbd56b2be85856ec790fa91f98f 268 Pfam PF01261 Xylose isomerase-like TIM barrel 29 195 1.9E-20 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SMALA_RS24190 fc4b4dbd56b2be85856ec790fa91f98f 268 SUPERFAMILY SSF51658 8 241 9.69E-32 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SMALA_RS05115 da788ab0991e32d76e846acf1109b487 219 Gene3D G3DSA:1.10.3630.10 1 194 2.0E-24 T 29-03-2018 SMALA_RS05115 da788ab0991e32d76e846acf1109b487 219 Pfam PF05719 Golgi phosphoprotein 3 (GPP34) 5 203 2.0E-28 T 29-03-2018 IPR008628 Golgi phosphoprotein 3-like GO:0070273 SMALA_RS41120 153ad0975184aa9136af0a998cad1713 243 Pfam PF01471 Putative peptidoglycan binding domain 46 103 1.3E-12 T 29-03-2018 IPR002477 Peptidoglycan binding-like SMALA_RS41120 153ad0975184aa9136af0a998cad1713 243 Gene3D G3DSA:3.30.1380.10 116 243 1.0E-28 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 SMALA_RS41120 153ad0975184aa9136af0a998cad1713 243 Pfam PF08291 Peptidase M15 116 228 3.6E-31 T 29-03-2018 IPR013230 Peptidase M15A, C-terminal KEGG: 00550+3.4.17.14|MetaCyc: PWY-6470 SMALA_RS41120 153ad0975184aa9136af0a998cad1713 243 SUPERFAMILY SSF55166 115 241 4.32E-22 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 SMALA_RS41120 153ad0975184aa9136af0a998cad1713 243 SUPERFAMILY SSF47090 34 105 2.88E-18 T 29-03-2018 IPR002477 Peptidoglycan binding-like SMALA_RS41120 153ad0975184aa9136af0a998cad1713 243 Gene3D G3DSA:1.10.101.10 32 115 5.8E-19 T 29-03-2018 IPR002477 Peptidoglycan binding-like SMALA_RS22630 6fb4dca9c6f1a207a7fda5add831c075 60 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 4 58 1.5E-25 T 29-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS22630 6fb4dca9c6f1a207a7fda5add831c075 60 Gene3D G3DSA:3.30.1390.20 4 58 8.2E-23 T 29-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain SMALA_RS22630 6fb4dca9c6f1a207a7fda5add831c075 60 PIRSF PIRSF002211 1 60 1.3E-27 T 29-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS22630 6fb4dca9c6f1a207a7fda5add831c075 60 Pfam PF00327 Ribosomal protein L30p/L7e 4 54 3.0E-16 T 29-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain SMALA_RS22630 6fb4dca9c6f1a207a7fda5add831c075 60 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 1 58 19.159 T 29-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS22630 6fb4dca9c6f1a207a7fda5add831c075 60 SUPERFAMILY SSF55129 1 60 5.1E-21 T 29-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain SMALA_RS06535 5ab9c8de569d6fba8f51c638c32654b8 227 Gene3D G3DSA:1.10.357.10 51 188 4.2E-25 T 29-03-2018 SMALA_RS06535 5ab9c8de569d6fba8f51c638c32654b8 227 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 10 23 6.2E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS06535 5ab9c8de569d6fba8f51c638c32654b8 227 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 31 54 6.2E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS06535 5ab9c8de569d6fba8f51c638c32654b8 227 SUPERFAMILY SSF46689 6 69 7.98E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS06535 5ab9c8de569d6fba8f51c638c32654b8 227 Gene3D G3DSA:1.10.10.60 6 50 4.9E-16 T 29-03-2018 SMALA_RS06535 5ab9c8de569d6fba8f51c638c32654b8 227 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 52 3.8E-14 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS20680 6e58103640e1c3d5ee1b037c21f0aa4e 134 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 13 131 4.0E-23 T 29-03-2018 IPR019920 F420-binding domain, putative SMALA_RS20680 6e58103640e1c3d5ee1b037c21f0aa4e 134 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 9 96 1.8E-11 T 29-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 SMALA_RS20680 6e58103640e1c3d5ee1b037c21f0aa4e 134 SUPERFAMILY SSF50475 10 132 7.86E-27 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS20680 6e58103640e1c3d5ee1b037c21f0aa4e 134 Gene3D G3DSA:2.30.110.10 2 133 1.0E-30 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS36930 53ebaf3efe3265ad8ee83a8feb15c739 319 ProSitePatterns PS00211 ABC transporters family signature. 128 142 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS36930 53ebaf3efe3265ad8ee83a8feb15c739 319 Pfam PF00005 ABC transporter 18 156 2.1E-24 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS36930 53ebaf3efe3265ad8ee83a8feb15c739 319 Gene3D G3DSA:3.40.50.300 1 297 1.3E-54 T 29-03-2018 SMALA_RS36930 53ebaf3efe3265ad8ee83a8feb15c739 319 SMART SM00382 26 204 2.6E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS36930 53ebaf3efe3265ad8ee83a8feb15c739 319 SUPERFAMILY SSF52540 1 218 2.61E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS00930 47a9359e4ba0046eecf1c1ef04744ac3 358 SMART SM00382 32 227 3.5E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS00930 47a9359e4ba0046eecf1c1ef04744ac3 358 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS00930 47a9359e4ba0046eecf1c1ef04744ac3 358 Pfam PF00005 ABC transporter 23 177 4.7E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS00930 47a9359e4ba0046eecf1c1ef04744ac3 358 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 229 295 4.7E-17 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMALA_RS00930 47a9359e4ba0046eecf1c1ef04744ac3 358 Gene3D G3DSA:3.40.50.300 1 323 2.5E-76 T 29-03-2018 SMALA_RS00930 47a9359e4ba0046eecf1c1ef04744ac3 358 SUPERFAMILY SSF52540 4 250 3.11E-65 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS00930 47a9359e4ba0046eecf1c1ef04744ac3 358 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 227 313 9.6E-15 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMALA_RS24590 097d2ab6b1b2b40070cb1a8e7cb2f54b 336 SUPERFAMILY SSF51445 47 325 6.33E-53 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS24590 097d2ab6b1b2b40070cb1a8e7cb2f54b 336 SMART SM00636 49 318 9.3E-7 T 29-03-2018 IPR011583 Chitinase II GO:0008061 SMALA_RS24590 097d2ab6b1b2b40070cb1a8e7cb2f54b 336 Pfam PF00704 Glycosyl hydrolases family 18 51 318 9.0E-27 T 29-03-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 SMALA_RS24590 097d2ab6b1b2b40070cb1a8e7cb2f54b 336 ProSitePatterns PS01095 Chitinases family 18 active site. 156 164 - T 29-03-2018 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 SMALA_RS24590 097d2ab6b1b2b40070cb1a8e7cb2f54b 336 Gene3D G3DSA:3.20.20.80 44 335 3.0E-46 T 29-03-2018 SMALA_RS30785 79cdd9241ae73e0900222e440f347a5c 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 143 166 2.1E-25 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 SMALA_RS30785 79cdd9241ae73e0900222e440f347a5c 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 187 208 2.1E-25 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 SMALA_RS30785 79cdd9241ae73e0900222e440f347a5c 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 45 65 2.1E-25 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 SMALA_RS30785 79cdd9241ae73e0900222e440f347a5c 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 94 110 2.1E-25 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 SMALA_RS30785 79cdd9241ae73e0900222e440f347a5c 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 67 83 2.1E-25 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 SMALA_RS30785 79cdd9241ae73e0900222e440f347a5c 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 218 242 2.1E-25 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 SMALA_RS30785 79cdd9241ae73e0900222e440f347a5c 275 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 221 235 - T 29-03-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 SMALA_RS30785 79cdd9241ae73e0900222e440f347a5c 275 SUPERFAMILY SSF56655 16 271 2.88E-58 T 29-03-2018 SMALA_RS30785 79cdd9241ae73e0900222e440f347a5c 275 Gene3D G3DSA:3.30.540.10 5 149 3.3E-34 T 29-03-2018 SMALA_RS30785 79cdd9241ae73e0900222e440f347a5c 275 Pfam PF00459 Inositol monophosphatase family 16 246 1.4E-52 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 SMALA_RS30785 79cdd9241ae73e0900222e440f347a5c 275 Gene3D G3DSA:3.40.190.80 150 267 3.6E-19 T 29-03-2018 SMALA_RS30785 79cdd9241ae73e0900222e440f347a5c 275 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 94 107 - T 29-03-2018 IPR020583 Inositol monophosphatase, metal-binding site SMALA_RS31640 bd8a923c20839cc3047cc98a5fb35a79 410 SUPERFAMILY SSF50118 1 71 5.36E-22 T 29-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor SMALA_RS31640 bd8a923c20839cc3047cc98a5fb35a79 410 SUPERFAMILY SSF55469 195 256 1.57E-5 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMALA_RS31640 bd8a923c20839cc3047cc98a5fb35a79 410 SUPERFAMILY SSF55469 316 406 1.57E-5 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMALA_RS31640 bd8a923c20839cc3047cc98a5fb35a79 410 Pfam PF08940 Domain of unknown function (DUF1918) 1 58 5.0E-26 T 29-03-2018 IPR015035 Domain of unknown function DUF1918 SMALA_RS31640 bd8a923c20839cc3047cc98a5fb35a79 410 Gene3D G3DSA:3.40.109.30 74 166 8.5E-12 T 29-03-2018 SMALA_RS31640 bd8a923c20839cc3047cc98a5fb35a79 410 SUPERFAMILY SSF55469 75 164 1.44E-9 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMALA_RS31640 bd8a923c20839cc3047cc98a5fb35a79 410 Gene3D G3DSA:3.40.109.10 193 409 1.0E-28 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMALA_RS33030 81db7c0dce5f852758ac4e28b4d9b4e7 597 Pfam PF02618 YceG-like family 290 587 6.0E-59 T 29-03-2018 IPR003770 Endolytic murein transglycosylase SMALA_RS33030 81db7c0dce5f852758ac4e28b4d9b4e7 597 Hamap MF_02065 Endolytic murein transglycosylase [mltG]. 247 593 26.899 T 29-03-2018 IPR003770 Endolytic murein transglycosylase SMALA_RS33030 81db7c0dce5f852758ac4e28b4d9b4e7 597 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 287 592 6.4E-41 T 29-03-2018 IPR003770 Endolytic murein transglycosylase SMALA_RS33030 81db7c0dce5f852758ac4e28b4d9b4e7 597 Gene3D G3DSA:3.30.160.60 562 596 2.4E-7 T 29-03-2018 SMALA_RS19505 a901e7b086abfbeb07721c1e37ceb670 507 Pfam PF00970 Oxidoreductase FAD-binding domain 277 369 2.5E-11 T 29-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 SMALA_RS19505 a901e7b086abfbeb07721c1e37ceb670 507 Pfam PF00175 Oxidoreductase NAD-binding domain 382 478 7.2E-14 T 29-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 SMALA_RS19505 a901e7b086abfbeb07721c1e37ceb670 507 Gene3D G3DSA:3.40.50.80 368 499 4.1E-19 T 29-03-2018 SMALA_RS19505 a901e7b086abfbeb07721c1e37ceb670 507 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 320 327 6.7E-5 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 SMALA_RS19505 a901e7b086abfbeb07721c1e37ceb670 507 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 380 399 6.7E-5 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 SMALA_RS19505 a901e7b086abfbeb07721c1e37ceb670 507 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 405 414 6.7E-5 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 SMALA_RS19505 a901e7b086abfbeb07721c1e37ceb670 507 SUPERFAMILY SSF63380 274 369 6.64E-24 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 SMALA_RS19505 a901e7b086abfbeb07721c1e37ceb670 507 PRINTS PR00410 Phenol hydroxylase reductase family signature 467 475 2.5E-15 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 SMALA_RS19505 a901e7b086abfbeb07721c1e37ceb670 507 PRINTS PR00410 Phenol hydroxylase reductase family signature 302 314 2.5E-15 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 SMALA_RS19505 a901e7b086abfbeb07721c1e37ceb670 507 PRINTS PR00410 Phenol hydroxylase reductase family signature 405 414 2.5E-15 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 SMALA_RS19505 a901e7b086abfbeb07721c1e37ceb670 507 PRINTS PR00410 Phenol hydroxylase reductase family signature 380 399 2.5E-15 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 SMALA_RS19505 a901e7b086abfbeb07721c1e37ceb670 507 SUPERFAMILY SSF52343 375 497 2.88E-27 T 29-03-2018 SMALA_RS19505 a901e7b086abfbeb07721c1e37ceb670 507 Gene3D G3DSA:1.10.490.10 134 268 5.7E-30 T 29-03-2018 SMALA_RS19505 a901e7b086abfbeb07721c1e37ceb670 507 SUPERFAMILY SSF46458 136 263 3.82E-31 T 29-03-2018 IPR009050 Globin-like SMALA_RS19505 a901e7b086abfbeb07721c1e37ceb670 507 Gene3D G3DSA:2.40.30.10 270 367 2.1E-20 T 29-03-2018 SMALA_RS19505 a901e7b086abfbeb07721c1e37ceb670 507 Pfam PF00042 Globin 138 229 1.9E-8 T 29-03-2018 IPR000971 Globin GO:0020037 SMALA_RS23400 890c3f92499d021cc356e85b0ba6b77e 327 SUPERFAMILY SSF53474 217 323 8.72E-63 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS23400 890c3f92499d021cc356e85b0ba6b77e 327 SUPERFAMILY SSF53474 8 188 8.72E-63 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS23400 890c3f92499d021cc356e85b0ba6b77e 327 Pfam PF00561 alpha/beta hydrolase fold 30 142 2.5E-23 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS23400 890c3f92499d021cc356e85b0ba6b77e 327 PRINTS PR00412 Epoxide hydrolase signature 56 71 1.0E-28 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS23400 890c3f92499d021cc356e85b0ba6b77e 327 PRINTS PR00412 Epoxide hydrolase signature 36 54 1.0E-28 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS23400 890c3f92499d021cc356e85b0ba6b77e 327 PRINTS PR00412 Epoxide hydrolase signature 299 321 1.0E-28 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS23400 890c3f92499d021cc356e85b0ba6b77e 327 PRINTS PR00412 Epoxide hydrolase signature 116 129 1.0E-28 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS23400 890c3f92499d021cc356e85b0ba6b77e 327 PRINTS PR00412 Epoxide hydrolase signature 102 115 1.0E-28 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS23400 890c3f92499d021cc356e85b0ba6b77e 327 Gene3D G3DSA:3.40.50.1820 9 326 2.0E-61 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS34150 50859f4b68b5465242c11b72936be349 160 PRINTS PR01759 Capsule biosynthesis protein CapC signature 25 42 5.2E-6 T 29-03-2018 IPR008338 Capsule biosynthesis protein CapC GO:0016020|GO:0045227 SMALA_RS34150 50859f4b68b5465242c11b72936be349 160 PRINTS PR01759 Capsule biosynthesis protein CapC signature 71 85 5.2E-6 T 29-03-2018 IPR008338 Capsule biosynthesis protein CapC GO:0016020|GO:0045227 SMALA_RS34150 50859f4b68b5465242c11b72936be349 160 Pfam PF14102 Capsule biosynthesis CapC 17 133 1.5E-31 T 29-03-2018 IPR008338 Capsule biosynthesis protein CapC GO:0016020|GO:0045227 SMALA_RS35630 c8d1941e09d31c66d03e770f9600418f 389 Gene3D G3DSA:1.10.260.40 4 78 9.8E-14 T 29-03-2018 SMALA_RS35630 c8d1941e09d31c66d03e770f9600418f 389 Pfam PF01381 Helix-turn-helix 17 67 9.0E-11 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS35630 c8d1941e09d31c66d03e770f9600418f 389 SUPERFAMILY SSF47413 10 71 2.53E-12 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS35630 c8d1941e09d31c66d03e770f9600418f 389 Gene3D G3DSA:1.25.40.10 79 376 5.6E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS35630 c8d1941e09d31c66d03e770f9600418f 389 SMART SM00530 12 67 7.6E-11 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS31965 729ad8dc739182525f56f9147dc3cc67 259 SMART SM00422 11 80 1.8E-20 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS31965 729ad8dc739182525f56f9147dc3cc67 259 Gene3D G3DSA:1.10.1660.10 7 66 8.4E-19 T 29-03-2018 SMALA_RS31965 729ad8dc739182525f56f9147dc3cc67 259 SUPERFAMILY SSF46955 11 81 3.66E-17 T 29-03-2018 IPR009061 Putative DNA-binding domain SMALA_RS31965 729ad8dc739182525f56f9147dc3cc67 259 Gene3D G3DSA:1.10.1660.10 67 141 4.2E-4 T 29-03-2018 SMALA_RS31965 729ad8dc739182525f56f9147dc3cc67 259 Pfam PF13411 MerR HTH family regulatory protein 12 79 5.8E-18 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS31965 729ad8dc739182525f56f9147dc3cc67 259 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 47 67 1.8E-9 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS31965 729ad8dc739182525f56f9147dc3cc67 259 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 23 36 1.8E-9 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS31965 729ad8dc739182525f56f9147dc3cc67 259 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 12 23 1.8E-9 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS20895 bde3721ef818dbd60fd0400db76f0b4f 105 Pfam PF11774 Lsr2 2 103 2.3E-35 T 29-03-2018 IPR024412 Lsr2 SMALA_RS20895 bde3721ef818dbd60fd0400db76f0b4f 105 ProDom PD026347 LSR2-LIKE LSR2 ANTIGEN IMMUNE PRECURSOR RESPONSE SIGNAL PLASMID LYSYL GP61 1 104 6.0E-43 T 29-03-2018 IPR024412 Lsr2 SMALA_RS18370 df583fcc0de16a0509df10f42856a998 156 SMART SM00347 36 135 1.0E-5 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS18370 df583fcc0de16a0509df10f42856a998 156 SUPERFAMILY SSF46785 15 146 5.92E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS18370 df583fcc0de16a0509df10f42856a998 156 Pfam PF13463 Winged helix DNA-binding domain 50 108 1.6E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS18370 df583fcc0de16a0509df10f42856a998 156 Gene3D G3DSA:1.10.10.10 10 150 5.6E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS18370 df583fcc0de16a0509df10f42856a998 156 ProSitePatterns PS01117 MarR-type HTH domain signature. 74 108 - T 29-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site SMALA_RS11645 a749ad06e66df3130400d2c7b9c6bbc7 337 Pfam PF01471 Putative peptidoglycan binding domain 272 328 1.4E-9 T 29-03-2018 IPR002477 Peptidoglycan binding-like SMALA_RS11645 a749ad06e66df3130400d2c7b9c6bbc7 337 Gene3D G3DSA:1.10.101.10 257 336 1.2E-16 T 29-03-2018 IPR002477 Peptidoglycan binding-like SMALA_RS11645 a749ad06e66df3130400d2c7b9c6bbc7 337 SUPERFAMILY SSF47090 261 330 3.06E-13 T 29-03-2018 IPR002477 Peptidoglycan binding-like SMALA_RS31710 845930161ce8233962b42ecdf72d7fbd 302 Gene3D G3DSA:3.40.190.10 185 269 2.2E-15 T 29-03-2018 SMALA_RS31710 845930161ce8233962b42ecdf72d7fbd 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 64 1.4E-19 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS31710 845930161ce8233962b42ecdf72d7fbd 302 SUPERFAMILY SSF46785 4 112 1.61E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS31710 845930161ce8233962b42ecdf72d7fbd 302 SUPERFAMILY SSF53850 91 300 1.16E-29 T 29-03-2018 SMALA_RS31710 845930161ce8233962b42ecdf72d7fbd 302 Gene3D G3DSA:3.40.190.10 92 184 9.9E-23 T 29-03-2018 SMALA_RS31710 845930161ce8233962b42ecdf72d7fbd 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 2.2E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS31710 845930161ce8233962b42ecdf72d7fbd 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 2.2E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS31710 845930161ce8233962b42ecdf72d7fbd 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 2.2E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS31710 845930161ce8233962b42ecdf72d7fbd 302 Gene3D G3DSA:1.10.10.10 1 85 1.3E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS31710 845930161ce8233962b42ecdf72d7fbd 302 Pfam PF03466 LysR substrate binding domain 89 297 1.5E-30 T 29-03-2018 IPR005119 LysR, substrate-binding SMALA_RS06825 a3d12198a9f071480419f250cc2ae881 550 SUPERFAMILY SSF51905 19 191 1.3E-66 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS06825 a3d12198a9f071480419f250cc2ae881 550 SUPERFAMILY SSF51905 280 382 1.3E-66 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS06825 a3d12198a9f071480419f250cc2ae881 550 Gene3D G3DSA:3.50.50.60 14 392 1.3E-56 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS06825 a3d12198a9f071480419f250cc2ae881 550 Pfam PF01494 FAD binding domain 19 353 1.6E-61 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 SMALA_RS06825 a3d12198a9f071480419f250cc2ae881 550 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 293 308 6.6E-35 T 29-03-2018 SMALA_RS06825 a3d12198a9f071480419f250cc2ae881 550 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 20 42 6.6E-35 T 29-03-2018 SMALA_RS06825 a3d12198a9f071480419f250cc2ae881 550 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 326 344 6.6E-35 T 29-03-2018 SMALA_RS06825 a3d12198a9f071480419f250cc2ae881 550 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 308 324 6.6E-35 T 29-03-2018 SMALA_RS06825 a3d12198a9f071480419f250cc2ae881 550 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 344 360 6.6E-35 T 29-03-2018 SMALA_RS06825 a3d12198a9f071480419f250cc2ae881 550 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 170 185 6.6E-35 T 29-03-2018 SMALA_RS11535 fc61f488799ca366de60ad10dc86ca4b 327 Pfam PF00107 Zinc-binding dehydrogenase 164 288 1.3E-23 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMALA_RS11535 fc61f488799ca366de60ad10dc86ca4b 327 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 86 8.4E-10 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS11535 fc61f488799ca366de60ad10dc86ca4b 327 SUPERFAMILY SSF50129 7 159 3.35E-40 T 29-03-2018 IPR011032 GroES-like SMALA_RS11535 fc61f488799ca366de60ad10dc86ca4b 327 Gene3D G3DSA:3.90.180.10 1 326 5.5E-77 T 29-03-2018 SMALA_RS11535 fc61f488799ca366de60ad10dc86ca4b 327 SUPERFAMILY SSF51735 129 298 2.67E-39 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS11535 fc61f488799ca366de60ad10dc86ca4b 327 SMART SM00829 11 325 1.7E-18 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS14635 96796b2e0ee0cefb688a57120e1c181f 72 Pfam PF10041 Uncharacterized conserved protein (DUF2277) 1 68 4.0E-26 T 29-03-2018 IPR018735 Protein of unknown function DUF2277 SMALA_RS12365 8088cf681647564d94cb4b8d2aef2c5d 431 SUPERFAMILY SSF51905 153 335 3.76E-28 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS12365 8088cf681647564d94cb4b8d2aef2c5d 431 Gene3D G3DSA:3.30.390.30 342 431 1.1E-29 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SMALA_RS12365 8088cf681647564d94cb4b8d2aef2c5d 431 SUPERFAMILY SSF55424 336 430 1.21E-26 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SMALA_RS12365 8088cf681647564d94cb4b8d2aef2c5d 431 Pfam PF14759 Reductase C-terminal 344 430 7.8E-18 T 29-03-2018 IPR028202 Reductase, C-terminal SMALA_RS12365 8088cf681647564d94cb4b8d2aef2c5d 431 Gene3D G3DSA:3.50.50.60 2 105 1.6E-14 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS12365 8088cf681647564d94cb4b8d2aef2c5d 431 Gene3D G3DSA:3.50.50.60 252 341 8.2E-10 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS12365 8088cf681647564d94cb4b8d2aef2c5d 431 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 104 122 1.8E-24 T 29-03-2018 SMALA_RS12365 8088cf681647564d94cb4b8d2aef2c5d 431 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 239 255 1.8E-24 T 29-03-2018 SMALA_RS12365 8088cf681647564d94cb4b8d2aef2c5d 431 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 1.8E-24 T 29-03-2018 SMALA_RS12365 8088cf681647564d94cb4b8d2aef2c5d 431 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 269 291 1.8E-24 T 29-03-2018 SMALA_RS12365 8088cf681647564d94cb4b8d2aef2c5d 431 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 153 171 1.8E-24 T 29-03-2018 SMALA_RS12365 8088cf681647564d94cb4b8d2aef2c5d 431 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 299 1.3E-61 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS12365 8088cf681647564d94cb4b8d2aef2c5d 431 Gene3D G3DSA:3.50.50.60 106 248 1.7E-30 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS12365 8088cf681647564d94cb4b8d2aef2c5d 431 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 1.5E-15 T 29-03-2018 SMALA_RS12365 8088cf681647564d94cb4b8d2aef2c5d 431 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 284 291 1.5E-15 T 29-03-2018 SMALA_RS12365 8088cf681647564d94cb4b8d2aef2c5d 431 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 153 178 1.5E-15 T 29-03-2018 SMALA_RS12365 8088cf681647564d94cb4b8d2aef2c5d 431 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 240 254 1.5E-15 T 29-03-2018 SMALA_RS12365 8088cf681647564d94cb4b8d2aef2c5d 431 SUPERFAMILY SSF51905 4 198 4.81E-44 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS01185 780b278c29493635b9cd11ad296aecc6 206 Gene3D G3DSA:1.10.10.10 128 206 1.6E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS01185 780b278c29493635b9cd11ad296aecc6 206 Pfam PF00196 Bacterial regulatory proteins, luxR family 145 199 2.3E-19 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS01185 780b278c29493635b9cd11ad296aecc6 206 SMART SM00421 142 199 1.2E-25 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS01185 780b278c29493635b9cd11ad296aecc6 206 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 175 187 9.5E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS01185 780b278c29493635b9cd11ad296aecc6 206 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 145 159 9.5E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS01185 780b278c29493635b9cd11ad296aecc6 206 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 159 175 9.5E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS01185 780b278c29493635b9cd11ad296aecc6 206 SUPERFAMILY SSF52172 2 163 3.89E-32 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS01185 780b278c29493635b9cd11ad296aecc6 206 SUPERFAMILY SSF46894 143 204 1.42E-18 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS01185 780b278c29493635b9cd11ad296aecc6 206 SMART SM00448 1 116 1.6E-35 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS01185 780b278c29493635b9cd11ad296aecc6 206 ProSitePatterns PS00622 LuxR-type HTH domain signature. 159 186 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS01185 780b278c29493635b9cd11ad296aecc6 206 Pfam PF00072 Response regulator receiver domain 4 117 5.4E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS01185 780b278c29493635b9cd11ad296aecc6 206 Gene3D G3DSA:3.40.50.2300 1 127 2.0E-37 T 29-03-2018 SMALA_RS07900 5fbea34eb78665eec22f66c2ecec8fe7 1864 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 1185 1191 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 SMALA_RS07900 5fbea34eb78665eec22f66c2ecec8fe7 1864 SUPERFAMILY SSF53335 1255 1356 1.92E-37 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS07900 5fbea34eb78665eec22f66c2ecec8fe7 1864 SUPERFAMILY SSF53335 1174 1204 1.92E-37 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS07900 5fbea34eb78665eec22f66c2ecec8fe7 1864 SUPERFAMILY SSF53335 460 474 1.92E-37 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS07900 5fbea34eb78665eec22f66c2ecec8fe7 1864 SUPERFAMILY SSF53335 502 551 1.92E-37 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS07900 5fbea34eb78665eec22f66c2ecec8fe7 1864 SUPERFAMILY SSF53335 352 418 1.92E-37 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS07900 5fbea34eb78665eec22f66c2ecec8fe7 1864 SUPERFAMILY SSF53335 621 775 1.92E-37 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS07900 5fbea34eb78665eec22f66c2ecec8fe7 1864 Gene3D G3DSA:3.40.50.150 628 1420 2.0E-36 T 29-03-2018 SMALA_RS38025 93d980b0318dfa33b02645c0b1ec9a7f 534 SUPERFAMILY SSF53850 51 518 2.35E-89 T 29-03-2018 SMALA_RS38025 93d980b0318dfa33b02645c0b1ec9a7f 534 Gene3D G3DSA:3.90.76.10 73 176 2.0E-20 T 29-03-2018 SMALA_RS38025 93d980b0318dfa33b02645c0b1ec9a7f 534 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 99 433 1.4E-63 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain SMALA_RS38025 93d980b0318dfa33b02645c0b1ec9a7f 534 Gene3D G3DSA:3.40.190.10 177 298 1.0E-25 T 29-03-2018 SMALA_RS38025 93d980b0318dfa33b02645c0b1ec9a7f 534 Gene3D G3DSA:3.10.105.10 299 493 4.4E-29 T 29-03-2018 SMALA_RS12285 0f2ad8e82e597ebf2461462856288e58 235 Gene3D G3DSA:1.10.10.10 172 233 7.6E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS12285 0f2ad8e82e597ebf2461462856288e58 235 Pfam PF00072 Response regulator receiver domain 25 136 5.0E-29 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS12285 0f2ad8e82e597ebf2461462856288e58 235 SUPERFAMILY SSF52172 22 146 9.68E-34 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS12285 0f2ad8e82e597ebf2461462856288e58 235 SMART SM00448 23 136 1.6E-31 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS12285 0f2ad8e82e597ebf2461462856288e58 235 SMART SM00421 170 227 6.8E-26 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS12285 0f2ad8e82e597ebf2461462856288e58 235 SUPERFAMILY SSF46894 166 234 9.52E-24 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS12285 0f2ad8e82e597ebf2461462856288e58 235 Gene3D G3DSA:3.40.50.2300 22 163 1.9E-37 T 29-03-2018 SMALA_RS12285 0f2ad8e82e597ebf2461462856288e58 235 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 173 187 2.5E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS12285 0f2ad8e82e597ebf2461462856288e58 235 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 187 203 2.5E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS12285 0f2ad8e82e597ebf2461462856288e58 235 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 203 215 2.5E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS12285 0f2ad8e82e597ebf2461462856288e58 235 ProSitePatterns PS00622 LuxR-type HTH domain signature. 187 214 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS12285 0f2ad8e82e597ebf2461462856288e58 235 Pfam PF00196 Bacterial regulatory proteins, luxR family 172 227 2.5E-19 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS02335 be9e968957a24c25a5296e01bd174729 408 Gene3D G3DSA:3.20.20.30 1 380 1.2E-69 T 29-03-2018 SMALA_RS02335 be9e968957a24c25a5296e01bd174729 408 SUPERFAMILY SSF51679 1 367 1.44E-66 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS02335 be9e968957a24c25a5296e01bd174729 408 Pfam PF00296 Luciferase-like monooxygenase 22 334 1.0E-42 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS34200 adb913be8de76b8a06f3a4c92074ddf9 462 SUPERFAMILY SSF103473 14 439 5.49E-45 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS34200 adb913be8de76b8a06f3a4c92074ddf9 462 Gene3D G3DSA:1.20.1250.20 229 438 8.9E-18 T 29-03-2018 SMALA_RS34200 adb913be8de76b8a06f3a4c92074ddf9 462 Pfam PF07690 Major Facilitator Superfamily 30 387 1.4E-29 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS34200 adb913be8de76b8a06f3a4c92074ddf9 462 Gene3D G3DSA:1.20.1250.20 13 214 2.5E-16 T 29-03-2018 SMALA_RS31390 3602405e671102d465f7f123310511fd 294 SUPERFAMILY SSF51658 8 284 3.54E-56 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SMALA_RS31390 3602405e671102d465f7f123310511fd 294 Gene3D G3DSA:3.20.20.150 2 289 3.0E-60 T 29-03-2018 SMALA_RS31390 3602405e671102d465f7f123310511fd 294 Pfam PF01261 Xylose isomerase-like TIM barrel 27 240 9.1E-35 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SMALA_RS31675 a72f9160774851a13070e5862ffc01cc 224 Gene3D G3DSA:1.10.150.240 22 75 3.1E-12 T 29-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 SMALA_RS31675 a72f9160774851a13070e5862ffc01cc 224 Gene3D G3DSA:3.40.50.1000 76 223 1.2E-22 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS31675 a72f9160774851a13070e5862ffc01cc 224 SUPERFAMILY SSF56784 6 219 1.52E-35 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS31675 a72f9160774851a13070e5862ffc01cc 224 Pfam PF13419 Haloacid dehalogenase-like hydrolase 8 195 5.4E-13 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS03030 20f918483dce94fa391e764dbb51116b 123 SUPERFAMILY SSF54593 3 120 1.48E-21 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS03030 20f918483dce94fa391e764dbb51116b 123 Gene3D G3DSA:3.10.180.10 2 123 1.8E-22 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS03030 20f918483dce94fa391e764dbb51116b 123 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 116 4.2E-6 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMALA_RS38250 964a24c0cbf01c986318711980b2acdc 2401 SUPERFAMILY SSF56801 432 988 1.96E-143 T 29-03-2018 SMALA_RS38250 964a24c0cbf01c986318711980b2acdc 2401 SUPERFAMILY SSF47336 2054 2125 1.96E-19 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS38250 964a24c0cbf01c986318711980b2acdc 2401 Gene3D G3DSA:2.30.38.10 1861 1942 2.4E-23 T 29-03-2018 SMALA_RS38250 964a24c0cbf01c986318711980b2acdc 2401 Pfam PF13193 AMP-binding enzyme C-terminal domain 1960 2035 2.6E-14 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS38250 964a24c0cbf01c986318711980b2acdc 2401 Pfam PF13193 AMP-binding enzyme C-terminal domain 872 947 5.0E-16 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS38250 964a24c0cbf01c986318711980b2acdc 2401 SUPERFAMILY SSF52777 1063 1235 7.89E-48 T 29-03-2018 SMALA_RS38250 964a24c0cbf01c986318711980b2acdc 2401 SUPERFAMILY SSF56801 1500 2073 1.06E-146 T 29-03-2018 SMALA_RS38250 964a24c0cbf01c986318711980b2acdc 2401 Pfam PF00501 AMP-binding enzyme 469 864 1.9E-86 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS38250 964a24c0cbf01c986318711980b2acdc 2401 Pfam PF00501 AMP-binding enzyme 1540 1952 3.0E-85 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS38250 964a24c0cbf01c986318711980b2acdc 2401 Gene3D G3DSA:3.40.50.980 612 763 6.9E-35 T 29-03-2018 SMALA_RS38250 964a24c0cbf01c986318711980b2acdc 2401 Gene3D G3DSA:3.40.50.1820 2136 2401 3.0E-26 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS38250 964a24c0cbf01c986318711980b2acdc 2401 SUPERFAMILY SSF52777 1248 1507 7.56E-60 T 29-03-2018 SMALA_RS38250 964a24c0cbf01c986318711980b2acdc 2401 Gene3D G3DSA:1.10.1200.10 2066 2135 4.4E-24 T 29-03-2018 SMALA_RS38250 964a24c0cbf01c986318711980b2acdc 2401 ProSitePatterns PS00455 Putative AMP-binding domain signature. 610 621 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS38250 964a24c0cbf01c986318711980b2acdc 2401 Pfam PF00550 Phosphopantetheine attachment site 978 1040 2.1E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS38250 964a24c0cbf01c986318711980b2acdc 2401 Pfam PF00550 Phosphopantetheine attachment site 2062 2125 6.9E-15 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS38250 964a24c0cbf01c986318711980b2acdc 2401 Gene3D G3DSA:2.30.38.10 776 857 2.2E-23 T 29-03-2018 SMALA_RS38250 964a24c0cbf01c986318711980b2acdc 2401 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 491 888 2.5E-123 T 29-03-2018 IPR010071 Amino acid adenylation domain SMALA_RS38250 964a24c0cbf01c986318711980b2acdc 2401 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1562 1976 2.0E-128 T 29-03-2018 IPR010071 Amino acid adenylation domain SMALA_RS38250 964a24c0cbf01c986318711980b2acdc 2401 Gene3D G3DSA:1.10.1200.10 979 1045 1.1E-24 T 29-03-2018 SMALA_RS38250 964a24c0cbf01c986318711980b2acdc 2401 SUPERFAMILY SSF47336 968 1040 3.53E-20 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS38250 964a24c0cbf01c986318711980b2acdc 2401 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1690 1701 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS38250 964a24c0cbf01c986318711980b2acdc 2401 SMART SM00823 Phosphopantetheine attachment site 2060 2129 1.2E-9 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS38250 964a24c0cbf01c986318711980b2acdc 2401 SMART SM00823 Phosphopantetheine attachment site 975 1044 1.9E-7 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS38250 964a24c0cbf01c986318711980b2acdc 2401 Gene3D G3DSA:3.40.50.980 462 611 2.2E-36 T 29-03-2018 SMALA_RS38250 964a24c0cbf01c986318711980b2acdc 2401 Gene3D G3DSA:3.40.50.980 1533 1694 3.5E-43 T 29-03-2018 SMALA_RS38250 964a24c0cbf01c986318711980b2acdc 2401 Gene3D G3DSA:3.30.559.10 3 207 3.9E-46 T 29-03-2018 SMALA_RS38250 964a24c0cbf01c986318711980b2acdc 2401 Gene3D G3DSA:3.30.559.10 1046 1262 4.2E-40 T 29-03-2018 SMALA_RS38250 964a24c0cbf01c986318711980b2acdc 2401 SMART SM00824 Thioesterase 2164 2397 0.0022 T 29-03-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 SMALA_RS38250 964a24c0cbf01c986318711980b2acdc 2401 SUPERFAMILY SSF52777 6 205 3.0E-43 T 29-03-2018 SMALA_RS38250 964a24c0cbf01c986318711980b2acdc 2401 Gene3D G3DSA:3.40.50.980 1695 1858 4.5E-32 T 29-03-2018 SMALA_RS38250 964a24c0cbf01c986318711980b2acdc 2401 Pfam PF00668 Condensation domain 8 447 4.6E-82 T 29-03-2018 IPR001242 Condensation domain SMALA_RS38250 964a24c0cbf01c986318711980b2acdc 2401 Pfam PF00668 Condensation domain 1059 1519 2.0E-89 T 29-03-2018 IPR001242 Condensation domain SMALA_RS38250 964a24c0cbf01c986318711980b2acdc 2401 ProSitePatterns PS00012 Phosphopantetheine attachment site. 999 1014 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS38250 964a24c0cbf01c986318711980b2acdc 2401 Pfam PF00975 Thioesterase domain 2150 2387 1.0E-29 T 29-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 SMALA_RS38250 964a24c0cbf01c986318711980b2acdc 2401 Gene3D G3DSA:3.30.300.30 1947 2065 2.6E-40 T 29-03-2018 SMALA_RS38250 964a24c0cbf01c986318711980b2acdc 2401 Gene3D G3DSA:3.30.300.30 859 978 4.7E-40 T 29-03-2018 SMALA_RS38250 964a24c0cbf01c986318711980b2acdc 2401 SUPERFAMILY SSF52777 190 438 2.0E-52 T 29-03-2018 SMALA_RS38250 964a24c0cbf01c986318711980b2acdc 2401 SUPERFAMILY SSF53474 2134 2398 1.59E-56 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS26855 caf96ea931c3e48dff16b57eaf773841 356 Pfam PF03462 PCRF domain 11 203 6.5E-66 T 29-03-2018 IPR005139 Peptide chain release factor GO:0006415 SMALA_RS26855 caf96ea931c3e48dff16b57eaf773841 356 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 227 243 - T 29-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 SMALA_RS26855 caf96ea931c3e48dff16b57eaf773841 356 Gene3D G3DSA:3.30.160.20 208 290 3.6E-33 T 29-03-2018 SMALA_RS26855 caf96ea931c3e48dff16b57eaf773841 356 Gene3D G3DSA:1.20.58.410 3 92 1.5E-18 T 29-03-2018 SMALA_RS26855 caf96ea931c3e48dff16b57eaf773841 356 SMART SM00937 63 178 2.5E-51 T 29-03-2018 IPR005139 Peptide chain release factor GO:0006415 SMALA_RS26855 caf96ea931c3e48dff16b57eaf773841 356 Pfam PF00472 RF-1 domain 211 320 1.3E-40 T 29-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 SMALA_RS26855 caf96ea931c3e48dff16b57eaf773841 356 SUPERFAMILY SSF75620 8 352 3.4E-127 T 29-03-2018 SMALA_RS26855 caf96ea931c3e48dff16b57eaf773841 356 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 2 353 5.9E-151 T 29-03-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 SMALA_RS26855 caf96ea931c3e48dff16b57eaf773841 356 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 1 356 37.993 T 29-03-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 SMALA_RS09225 6793e604e3a92a42166b873ca0714413 364 SUPERFAMILY SSF51556 53 327 2.94E-60 T 29-03-2018 IPR032466 Metal-dependent hydrolase SMALA_RS09225 6793e604e3a92a42166b873ca0714413 364 Pfam PF01979 Amidohydrolase family 173 363 9.1E-12 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 SMALA_RS09225 6793e604e3a92a42166b873ca0714413 364 Gene3D G3DSA:2.30.40.10 1 86 2.7E-7 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS09225 6793e604e3a92a42166b873ca0714413 364 Gene3D G3DSA:3.20.20.140 87 309 1.1E-26 T 29-03-2018 SMALA_RS09225 6793e604e3a92a42166b873ca0714413 364 SUPERFAMILY SSF51338 4 52 5.62E-5 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS09225 6793e604e3a92a42166b873ca0714413 364 SUPERFAMILY SSF51338 326 363 5.62E-5 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS09225 6793e604e3a92a42166b873ca0714413 364 Gene3D G3DSA:2.30.40.10 310 363 8.7E-4 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS04290 8cd4b361d7600765d0d560d4b4e8aa23 293 SUPERFAMILY SSF161098 80 261 4.25E-14 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS04290 8cd4b361d7600765d0d560d4b4e8aa23 293 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 97 270 4.2E-16 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS04290 8cd4b361d7600765d0d560d4b4e8aa23 293 Gene3D G3DSA:1.10.3720.10 10 269 3.5E-24 T 29-03-2018 SMALA_RS28475 1c4dfe7411733276eeb7ec895e070845 1035 SUPERFAMILY SSF52540 525 695 1.8E-47 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS28475 1c4dfe7411733276eeb7ec895e070845 1035 Gene3D G3DSA:3.40.50.300 523 709 1.7E-37 T 29-03-2018 SMALA_RS28475 1c4dfe7411733276eeb7ec895e070845 1035 Pfam PF11987 Translation-initiation factor 2 824 925 1.3E-33 T 29-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 SMALA_RS28475 1c4dfe7411733276eeb7ec895e070845 1035 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 3 1034 16.679 T 29-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 SMALA_RS28475 1c4dfe7411733276eeb7ec895e070845 1035 SUPERFAMILY SSF50447 706 789 2.89E-24 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain SMALA_RS28475 1c4dfe7411733276eeb7ec895e070845 1035 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 531 690 1.5E-29 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 SMALA_RS28475 1c4dfe7411733276eeb7ec895e070845 1035 PRINTS PR00315 GTP-binding elongation factor signature 636 645 1.2E-9 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMALA_RS28475 1c4dfe7411733276eeb7ec895e070845 1035 PRINTS PR00315 GTP-binding elongation factor signature 584 594 1.2E-9 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMALA_RS28475 1c4dfe7411733276eeb7ec895e070845 1035 PRINTS PR00315 GTP-binding elongation factor signature 600 611 1.2E-9 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMALA_RS28475 1c4dfe7411733276eeb7ec895e070845 1035 PRINTS PR00315 GTP-binding elongation factor signature 532 545 1.2E-9 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMALA_RS28475 1c4dfe7411733276eeb7ec895e070845 1035 Gene3D G3DSA:2.40.30.10 710 834 4.7E-32 T 29-03-2018 SMALA_RS28475 1c4dfe7411733276eeb7ec895e070845 1035 SUPERFAMILY SSF50447 936 1034 4.64E-24 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain SMALA_RS28475 1c4dfe7411733276eeb7ec895e070845 1035 SUPERFAMILY SSF52156 813 942 1.83E-35 T 29-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 SMALA_RS28475 1c4dfe7411733276eeb7ec895e070845 1035 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 449 494 1.5E-7 T 29-03-2018 IPR006847 Translation initiation factor IF-2, N-terminal SMALA_RS28475 1c4dfe7411733276eeb7ec895e070845 1035 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 2 51 1.7E-12 T 29-03-2018 IPR006847 Translation initiation factor IF-2, N-terminal SMALA_RS28475 1c4dfe7411733276eeb7ec895e070845 1035 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 441 1034 2.1E-228 T 29-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 SMALA_RS28475 1c4dfe7411733276eeb7ec895e070845 1035 Gene3D G3DSA:3.30.56.50 4 46 7.5E-11 T 29-03-2018 SMALA_RS28475 1c4dfe7411733276eeb7ec895e070845 1035 Gene3D G3DSA:3.30.56.50 449 488 0.0023 T 29-03-2018 SMALA_RS28475 1c4dfe7411733276eeb7ec895e070845 1035 Gene3D G3DSA:2.40.30.10 936 1035 5.7E-24 T 29-03-2018 SMALA_RS28475 1c4dfe7411733276eeb7ec895e070845 1035 Pfam PF00009 Elongation factor Tu GTP binding domain 533 693 5.8E-33 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMALA_RS28475 1c4dfe7411733276eeb7ec895e070845 1035 Gene3D G3DSA:3.40.50.10050 835 914 1.9E-24 T 29-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 SMALA_RS28475 1c4dfe7411733276eeb7ec895e070845 1035 ProSitePatterns PS01176 Initiation factor 2 signature. 987 1009 - T 29-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 SMALA_RS27950 c5247ab33b1bce8dde329609720d4608 333 SUPERFAMILY SSF51735 4 179 1.31E-52 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS27950 c5247ab33b1bce8dde329609720d4608 333 Gene3D G3DSA:1.10.1040.10 180 330 4.7E-51 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMALA_RS27950 c5247ab33b1bce8dde329609720d4608 333 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 5 160 1.6E-50 T 29-03-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 SMALA_RS27950 c5247ab33b1bce8dde329609720d4608 333 SUPERFAMILY SSF48179 179 331 9.52E-55 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMALA_RS27950 c5247ab33b1bce8dde329609720d4608 333 PIRSF PIRSF000114 1 332 5.4E-100 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 SMALA_RS27950 c5247ab33b1bce8dde329609720d4608 333 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 238 255 5.8E-47 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 SMALA_RS27950 c5247ab33b1bce8dde329609720d4608 333 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 6 23 5.8E-47 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 SMALA_RS27950 c5247ab33b1bce8dde329609720d4608 333 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 173 197 5.8E-47 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 SMALA_RS27950 c5247ab33b1bce8dde329609720d4608 333 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 198 222 5.8E-47 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 SMALA_RS27950 c5247ab33b1bce8dde329609720d4608 333 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 56 83 5.8E-47 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 SMALA_RS27950 c5247ab33b1bce8dde329609720d4608 333 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 133 153 5.8E-47 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 SMALA_RS27950 c5247ab33b1bce8dde329609720d4608 333 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 188 209 - T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 SMALA_RS27950 c5247ab33b1bce8dde329609720d4608 333 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 180 317 1.7E-49 T 29-03-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 SMALA_RS27950 c5247ab33b1bce8dde329609720d4608 333 Gene3D G3DSA:3.40.50.720 1 179 2.8E-46 T 29-03-2018 SMALA_RS27950 c5247ab33b1bce8dde329609720d4608 333 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 2 322 37.486 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 SMALA_RS34055 6186070bd36d0d3d0bd2e7b22551a6f9 529 Pfam PF13458 Periplasmic binding protein 123 428 2.7E-9 T 29-03-2018 IPR028081 Leucine-binding protein domain SMALA_RS34055 6186070bd36d0d3d0bd2e7b22551a6f9 529 Gene3D G3DSA:3.40.50.2300 237 433 9.3E-8 T 29-03-2018 SMALA_RS34055 6186070bd36d0d3d0bd2e7b22551a6f9 529 SUPERFAMILY SSF53822 100 431 7.07E-18 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SMALA_RS34055 6186070bd36d0d3d0bd2e7b22551a6f9 529 Gene3D G3DSA:3.40.50.2300 99 236 6.5E-5 T 29-03-2018 SMALA_RS18330 9ed889dd0195676b5d767988806c5303 397 Gene3D G3DSA:1.50.10.10 25 397 1.7E-100 T 29-03-2018 SMALA_RS18330 9ed889dd0195676b5d767988806c5303 397 PRINTS PR00735 Glycosyl hydrolase family 8 signature 196 213 6.7E-17 T 29-03-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 SMALA_RS18330 9ed889dd0195676b5d767988806c5303 397 PRINTS PR00735 Glycosyl hydrolase family 8 signature 71 84 6.7E-17 T 29-03-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 SMALA_RS18330 9ed889dd0195676b5d767988806c5303 397 PRINTS PR00735 Glycosyl hydrolase family 8 signature 270 279 6.7E-17 T 29-03-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 SMALA_RS18330 9ed889dd0195676b5d767988806c5303 397 PRINTS PR00735 Glycosyl hydrolase family 8 signature 133 151 6.7E-17 T 29-03-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 SMALA_RS18330 9ed889dd0195676b5d767988806c5303 397 PRINTS PR00735 Glycosyl hydrolase family 8 signature 239 250 6.7E-17 T 29-03-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 SMALA_RS18330 9ed889dd0195676b5d767988806c5303 397 SUPERFAMILY SSF48208 64 396 1.43E-70 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 SMALA_RS18330 9ed889dd0195676b5d767988806c5303 397 Pfam PF01270 Glycosyl hydrolases family 8 39 248 1.6E-15 T 29-03-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 SMALA_RS02280 24e9a5bc97e9e44eb1ad79b0c0e64fb1 210 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 39 193 1.3E-20 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS02280 24e9a5bc97e9e44eb1ad79b0c0e64fb1 210 SUPERFAMILY SSF88659 139 194 3.27E-11 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS02280 24e9a5bc97e9e44eb1ad79b0c0e64fb1 210 SUPERFAMILY SSF88946 22 124 3.92E-24 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS02280 24e9a5bc97e9e44eb1ad79b0c0e64fb1 210 Gene3D G3DSA:1.10.1740.10 25 102 4.5E-22 T 29-03-2018 SMALA_RS02280 24e9a5bc97e9e44eb1ad79b0c0e64fb1 210 Pfam PF04542 Sigma-70 region 2 44 110 1.3E-14 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS02280 24e9a5bc97e9e44eb1ad79b0c0e64fb1 210 Pfam PF08281 Sigma-70, region 4 141 191 4.3E-14 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS02280 24e9a5bc97e9e44eb1ad79b0c0e64fb1 210 Gene3D G3DSA:1.10.10.10 103 199 2.0E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS09330 af57be3e38c26323933910810718b597 308 Gene3D G3DSA:1.10.3720.10 23 303 2.0E-51 T 29-03-2018 SMALA_RS09330 af57be3e38c26323933910810718b597 308 SUPERFAMILY SSF161098 67 295 1.44E-57 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS09330 af57be3e38c26323933910810718b597 308 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 99 299 1.3E-17 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS28500 f9a1159c04cf817acc1b23cd1ca2a38e 1104 Gene3D G3DSA:3.40.50.300 764 1013 1.5E-25 T 29-03-2018 SMALA_RS28500 f9a1159c04cf817acc1b23cd1ca2a38e 1104 Pfam PF13614 AAA domain 765 912 1.4E-10 T 29-03-2018 IPR025669 AAA domain SMALA_RS28500 f9a1159c04cf817acc1b23cd1ca2a38e 1104 SUPERFAMILY SSF52540 763 999 6.81E-25 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS04255 35a5b16e9d6303e7991bf4a2bd9882b2 322 Pfam PF02678 Pirin 45 141 7.9E-25 T 29-03-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 SMALA_RS04255 35a5b16e9d6303e7991bf4a2bd9882b2 322 PIRSF PIRSF006232 20 303 1.4E-81 T 29-03-2018 IPR012093 Pirin Reactome: R-HSA-8935690 SMALA_RS04255 35a5b16e9d6303e7991bf4a2bd9882b2 322 SUPERFAMILY SSF51182 33 302 4.24E-69 T 29-03-2018 IPR011051 RmlC-like cupin domain SMALA_RS04255 35a5b16e9d6303e7991bf4a2bd9882b2 322 Pfam PF05726 Pirin C-terminal cupin domain 194 292 1.6E-21 T 29-03-2018 IPR008778 Pirin, C-terminal domain Reactome: R-HSA-8935690 SMALA_RS04255 35a5b16e9d6303e7991bf4a2bd9882b2 322 Gene3D G3DSA:2.60.120.10 18 267 1.3E-60 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SMALA_RS37160 3f6910a7eab52d2ab57613ded753df85 386 Gene3D G3DSA:2.70.70.10 237 381 7.9E-40 T 29-03-2018 SMALA_RS37160 3f6910a7eab52d2ab57613ded753df85 386 Pfam PF06737 Transglycosylase-like domain 43 118 5.6E-35 T 29-03-2018 IPR010618 Transglycosylase-like SMALA_RS37160 3f6910a7eab52d2ab57613ded753df85 386 SUPERFAMILY SSF51261 239 379 2.98E-43 T 29-03-2018 IPR011055 Duplicated hybrid motif SMALA_RS37160 3f6910a7eab52d2ab57613ded753df85 386 SUPERFAMILY SSF54106 175 223 3.79E-5 T 29-03-2018 IPR018392 LysM domain SMALA_RS37160 3f6910a7eab52d2ab57613ded753df85 386 Pfam PF01551 Peptidase family M23 278 365 2.7E-30 T 29-03-2018 IPR016047 Peptidase M23 SMALA_RS37160 3f6910a7eab52d2ab57613ded753df85 386 Gene3D G3DSA:3.10.350.10 168 236 1.5E-13 T 29-03-2018 SMALA_RS37160 3f6910a7eab52d2ab57613ded753df85 386 SMART SM00257 174 223 1.4E-4 T 29-03-2018 IPR018392 LysM domain SMALA_RS37160 3f6910a7eab52d2ab57613ded753df85 386 Pfam PF01476 LysM domain 175 223 7.8E-8 T 29-03-2018 IPR018392 LysM domain SMALA_RS37160 3f6910a7eab52d2ab57613ded753df85 386 Gene3D G3DSA:1.10.530.10 14 125 1.4E-31 T 29-03-2018 SMALA_RS37160 3f6910a7eab52d2ab57613ded753df85 386 SUPERFAMILY SSF53955 45 121 4.67E-32 T 29-03-2018 IPR023346 Lysozyme-like domain SMALA_RS24930 516f670f9b3237fdc59748c95b86f717 226 Pfam PF09922 Cell wall-active antibiotics response 4TMS YvqF 120 192 4.9E-10 T 29-03-2018 IPR024425 Cell wall-active antibiotics response 4TMS YvqF SMALA_RS24930 516f670f9b3237fdc59748c95b86f717 226 Pfam PF08044 Domain of unknown function (DUF1707) 30 82 2.1E-22 T 29-03-2018 IPR012551 Protein of unknown function DUF1707 SMALA_RS30820 f8ac611d6edd59509a07179e0b8c60d7 491 Pfam PF06029 AlkA N-terminal domain 199 314 2.2E-29 T 29-03-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal SMALA_RS30820 f8ac611d6edd59509a07179e0b8c60d7 491 Pfam PF12833 Helix-turn-helix domain 106 185 9.9E-17 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS30820 f8ac611d6edd59509a07179e0b8c60d7 491 Gene3D G3DSA:1.10.1670.10 445 483 8.7E-14 T 29-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 SMALA_RS30820 f8ac611d6edd59509a07179e0b8c60d7 491 Pfam PF02805 Metal binding domain of Ada 8 71 2.0E-28 T 29-03-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 SMALA_RS30820 f8ac611d6edd59509a07179e0b8c60d7 491 SUPERFAMILY SSF55945 199 294 1.88E-25 T 29-03-2018 SMALA_RS30820 f8ac611d6edd59509a07179e0b8c60d7 491 Gene3D G3DSA:3.30.310.20 199 300 2.0E-35 T 29-03-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal SMALA_RS30820 f8ac611d6edd59509a07179e0b8c60d7 491 SUPERFAMILY SSF48150 303 479 3.31E-37 T 29-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 SMALA_RS30820 f8ac611d6edd59509a07179e0b8c60d7 491 SMART SM01009 199 314 2.6E-45 T 29-03-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal SMALA_RS30820 f8ac611d6edd59509a07179e0b8c60d7 491 SMART SM00342 100 183 7.8E-17 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS30820 f8ac611d6edd59509a07179e0b8c60d7 491 Gene3D G3DSA:1.10.340.30 301 444 1.5E-25 T 29-03-2018 SMALA_RS30820 f8ac611d6edd59509a07179e0b8c60d7 491 Gene3D G3DSA:3.40.10.10 1 73 1.5E-25 T 29-03-2018 IPR035451 Ada-like domain SMALA_RS30820 f8ac611d6edd59509a07179e0b8c60d7 491 Gene3D G3DSA:1.10.10.60 80 137 5.6E-4 T 29-03-2018 SMALA_RS30820 f8ac611d6edd59509a07179e0b8c60d7 491 SUPERFAMILY SSF57884 2 83 1.19E-31 T 29-03-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 SMALA_RS30820 f8ac611d6edd59509a07179e0b8c60d7 491 Gene3D G3DSA:1.10.10.60 138 195 1.0E-9 T 29-03-2018 SMALA_RS30820 f8ac611d6edd59509a07179e0b8c60d7 491 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 137 179 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 SMALA_RS30820 f8ac611d6edd59509a07179e0b8c60d7 491 SMART SM00478 324 481 9.9E-28 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 SMALA_RS30820 f8ac611d6edd59509a07179e0b8c60d7 491 SUPERFAMILY SSF46689 137 187 1.93E-7 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS08945 63298881ac19fb0c40de48752e7f3e37 149 SUPERFAMILY SSF46785 10 142 1.06E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS08945 63298881ac19fb0c40de48752e7f3e37 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 103 1.4E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS08945 63298881ac19fb0c40de48752e7f3e37 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 68 83 1.4E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS08945 63298881ac19fb0c40de48752e7f3e37 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 117 137 1.4E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS08945 63298881ac19fb0c40de48752e7f3e37 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 51 67 1.4E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS08945 63298881ac19fb0c40de48752e7f3e37 149 ProSitePatterns PS01117 MarR-type HTH domain signature. 66 100 - T 29-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site SMALA_RS08945 63298881ac19fb0c40de48752e7f3e37 149 Gene3D G3DSA:1.10.10.10 3 148 4.5E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS08945 63298881ac19fb0c40de48752e7f3e37 149 SMART SM00347 27 127 5.2E-17 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS08945 63298881ac19fb0c40de48752e7f3e37 149 Pfam PF01047 MarR family 40 91 3.1E-15 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS40410 dd5b0028b761662b974f74d12801bc70 350 SUPERFAMILY SSF47413 1 61 5.16E-15 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS40410 dd5b0028b761662b974f74d12801bc70 350 Gene3D G3DSA:3.40.50.2300 59 174 9.1E-27 T 29-03-2018 SMALA_RS40410 dd5b0028b761662b974f74d12801bc70 350 Gene3D G3DSA:3.40.50.2300 175 308 2.1E-41 T 29-03-2018 SMALA_RS40410 dd5b0028b761662b974f74d12801bc70 350 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 50 1.7E-14 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS40410 dd5b0028b761662b974f74d12801bc70 350 Gene3D G3DSA:1.10.260.40 2 58 1.2E-20 T 29-03-2018 SMALA_RS40410 dd5b0028b761662b974f74d12801bc70 350 Pfam PF13377 Periplasmic binding protein-like domain 172 335 2.0E-34 T 29-03-2018 SMALA_RS40410 dd5b0028b761662b974f74d12801bc70 350 SUPERFAMILY SSF53822 63 341 5.3E-62 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SMALA_RS40410 dd5b0028b761662b974f74d12801bc70 350 SMART SM00354 1 73 1.9E-24 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS41365 375203fdb16e9765d57e2d971e5fc775 317 Pfam PF01636 Phosphotransferase enzyme family 50 255 5.1E-23 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase SMALA_RS41365 375203fdb16e9765d57e2d971e5fc775 317 Gene3D G3DSA:3.30.200.20 13 112 3.3E-8 T 29-03-2018 SMALA_RS41365 375203fdb16e9765d57e2d971e5fc775 317 Gene3D G3DSA:3.90.1200.10 115 315 3.9E-12 T 29-03-2018 SMALA_RS41365 375203fdb16e9765d57e2d971e5fc775 317 SUPERFAMILY SSF56112 17 271 6.12E-27 T 29-03-2018 IPR011009 Protein kinase-like domain SMALA_RS24330 de2ff7c7afc5410075ddaf5feefe5b4e 123 SUPERFAMILY SSF47413 49 112 1.07E-10 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS24330 de2ff7c7afc5410075ddaf5feefe5b4e 123 Pfam PF13560 Helix-turn-helix domain 49 105 6.7E-9 T 29-03-2018 SMALA_RS24330 de2ff7c7afc5410075ddaf5feefe5b4e 123 Gene3D G3DSA:1.10.260.40 40 102 1.4E-11 T 29-03-2018 SMALA_RS24330 de2ff7c7afc5410075ddaf5feefe5b4e 123 SMART SM00530 53 108 1.5E-5 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS08310 6ed321753484101318c16d96eef22bb5 552 Gene3D G3DSA:3.30.200.20 4 102 1.4E-18 T 29-03-2018 SMALA_RS08310 6ed321753484101318c16d96eef22bb5 552 SUPERFAMILY SSF56112 14 272 3.1E-64 T 29-03-2018 IPR011009 Protein kinase-like domain SMALA_RS08310 6ed321753484101318c16d96eef22bb5 552 Pfam PF00069 Protein kinase domain 18 267 1.4E-42 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMALA_RS08310 6ed321753484101318c16d96eef22bb5 552 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 140 152 - T 29-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMALA_RS08310 6ed321753484101318c16d96eef22bb5 552 Gene3D G3DSA:1.10.510.10 103 277 5.1E-45 T 29-03-2018 SMALA_RS08310 6ed321753484101318c16d96eef22bb5 552 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 24 47 - T 29-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 SMALA_RS08310 6ed321753484101318c16d96eef22bb5 552 SMART SM00220 18 274 9.1E-61 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMALA_RS08530 dd263684d7c93fad6db0a626ca238a0c 320 Gene3D G3DSA:3.40.190.10 182 254 1.2E-15 T 29-03-2018 SMALA_RS08530 dd263684d7c93fad6db0a626ca238a0c 320 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 76 301 2.0E-41 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SMALA_RS08530 dd263684d7c93fad6db0a626ca238a0c 320 SMART SM00062 71 304 2.4E-26 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SMALA_RS08530 dd263684d7c93fad6db0a626ca238a0c 320 SUPERFAMILY SSF53850 61 302 1.38E-43 T 29-03-2018 SMALA_RS08530 dd263684d7c93fad6db0a626ca238a0c 320 Gene3D G3DSA:3.40.190.10 57 181 1.0E-20 T 29-03-2018 SMALA_RS39235 07ed879e458430db810b30d0cebd8fde 310 Pfam PF00685 Sulfotransferase domain 26 282 5.6E-33 T 29-03-2018 IPR000863 Sulfotransferase domain GO:0008146 SMALA_RS39235 07ed879e458430db810b30d0cebd8fde 310 Gene3D G3DSA:3.40.50.300 4 286 1.8E-39 T 29-03-2018 SMALA_RS39235 07ed879e458430db810b30d0cebd8fde 310 SUPERFAMILY SSF52540 14 285 6.02E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS08200 96571ccbb388f942118ff01502715640 383 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 18 360 1.5E-128 T 29-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 SMALA_RS08200 96571ccbb388f942118ff01502715640 383 PIRSF PIRSF004640 12 371 3.9E-144 T 29-03-2018 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 SMALA_RS08200 96571ccbb388f942118ff01502715640 383 Gene3D G3DSA:3.20.20.120 18 202 1.0E-20 T 29-03-2018 IPR029065 Enolase C-terminal domain-like SMALA_RS08200 96571ccbb388f942118ff01502715640 383 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 16 367 33.546 T 29-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 SMALA_RS08200 96571ccbb388f942118ff01502715640 383 Pfam PF04551 GcpE protein 21 361 4.3E-134 T 29-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 SMALA_RS08200 96571ccbb388f942118ff01502715640 383 SUPERFAMILY SSF51717 47 220 7.85E-10 T 29-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMALA_RS08200 96571ccbb388f942118ff01502715640 383 SUPERFAMILY SSF56014 276 362 2.55E-11 T 29-03-2018 SMALA_RS21410 485a6451d22cb3708434bb5ba3733349 177 Pfam PF13302 Acetyltransferase (GNAT) domain 9 149 1.0E-11 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SMALA_RS21410 485a6451d22cb3708434bb5ba3733349 177 SUPERFAMILY SSF55729 8 153 1.75E-18 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS21410 485a6451d22cb3708434bb5ba3733349 177 Gene3D G3DSA:3.40.630.30 3 175 2.2E-18 T 29-03-2018 SMALA_RS05870 72d013f3ff59e83e03613902ad6eafe3 283 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.4E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS05870 72d013f3ff59e83e03613902ad6eafe3 283 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.4E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS05870 72d013f3ff59e83e03613902ad6eafe3 283 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.4E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS05870 72d013f3ff59e83e03613902ad6eafe3 283 Pfam PF03466 LysR substrate binding domain 87 276 3.3E-16 T 29-03-2018 IPR005119 LysR, substrate-binding SMALA_RS05870 72d013f3ff59e83e03613902ad6eafe3 283 SUPERFAMILY SSF53850 88 273 3.88E-17 T 29-03-2018 SMALA_RS05870 72d013f3ff59e83e03613902ad6eafe3 283 Gene3D G3DSA:3.40.190.10 176 253 5.2E-5 T 29-03-2018 SMALA_RS05870 72d013f3ff59e83e03613902ad6eafe3 283 Gene3D G3DSA:3.40.190.10 86 175 6.6E-14 T 29-03-2018 SMALA_RS05870 72d013f3ff59e83e03613902ad6eafe3 283 Gene3D G3DSA:1.10.10.10 1 83 5.4E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS05870 72d013f3ff59e83e03613902ad6eafe3 283 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 9.3E-22 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS05870 72d013f3ff59e83e03613902ad6eafe3 283 SUPERFAMILY SSF46785 1 84 8.61E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS40285 70085e669f0cc9f71e85f60176d052f3 401 Gene3D G3DSA:3.50.50.60 261 347 5.7E-8 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS40285 70085e669f0cc9f71e85f60176d052f3 401 SUPERFAMILY SSF51905 3 121 2.14E-29 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS40285 70085e669f0cc9f71e85f60176d052f3 401 SUPERFAMILY SSF51905 154 172 2.14E-29 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS40285 70085e669f0cc9f71e85f60176d052f3 401 SUPERFAMILY SSF51905 213 341 2.14E-29 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS40285 70085e669f0cc9f71e85f60176d052f3 401 Gene3D G3DSA:3.50.50.60 105 256 1.6E-23 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS40285 70085e669f0cc9f71e85f60176d052f3 401 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 317 8.7E-46 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS40285 70085e669f0cc9f71e85f60176d052f3 401 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 284 302 5.0E-7 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMALA_RS40285 70085e669f0cc9f71e85f60176d052f3 401 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 3 25 5.0E-7 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMALA_RS40285 70085e669f0cc9f71e85f60176d052f3 401 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 104 112 5.0E-7 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMALA_RS40285 70085e669f0cc9f71e85f60176d052f3 401 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 274 296 1.1E-14 T 29-03-2018 SMALA_RS40285 70085e669f0cc9f71e85f60176d052f3 401 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 155 173 1.1E-14 T 29-03-2018 SMALA_RS40285 70085e669f0cc9f71e85f60176d052f3 401 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 1.1E-14 T 29-03-2018 SMALA_RS40285 70085e669f0cc9f71e85f60176d052f3 401 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 103 121 1.1E-14 T 29-03-2018 SMALA_RS40285 70085e669f0cc9f71e85f60176d052f3 401 Gene3D G3DSA:3.50.50.60 1 104 5.6E-9 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS39275 2cb05481f65126a478b8b214fb10f405 743 Gene3D G3DSA:3.30.470.20 447 734 3.5E-50 T 29-03-2018 SMALA_RS39275 2cb05481f65126a478b8b214fb10f405 743 SUPERFAMILY SSF56059 430 651 2.83E-40 T 29-03-2018 SMALA_RS39275 2cb05481f65126a478b8b214fb10f405 743 Pfam PF13535 ATP-grasp domain 478 625 5.0E-25 T 29-03-2018 SMALA_RS39275 2cb05481f65126a478b8b214fb10f405 743 SMART SM01209 442 622 0.0021 T 29-03-2018 SMALA_RS39275 2cb05481f65126a478b8b214fb10f405 743 Gene3D G3DSA:3.40.50.20 344 446 2.0E-9 T 29-03-2018 SMALA_RS39275 2cb05481f65126a478b8b214fb10f405 743 SUPERFAMILY SSF53686 4 302 6.42E-65 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMALA_RS39275 2cb05481f65126a478b8b214fb10f405 743 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 8 289 7.0E-46 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMALA_RS39275 2cb05481f65126a478b8b214fb10f405 743 Gene3D G3DSA:3.40.50.1100 138 305 7.3E-33 T 29-03-2018 SMALA_RS39275 2cb05481f65126a478b8b214fb10f405 743 Gene3D G3DSA:3.40.50.1100 39 137 1.4E-19 T 29-03-2018 SMALA_RS22515 11da00683a243ddb744f2db7950d9f40 397 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 53 68 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site SMALA_RS22515 11da00683a243ddb744f2db7950d9f40 397 SUPERFAMILY SSF50465 305 397 5.47E-36 T 29-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal SMALA_RS22515 11da00683a243ddb744f2db7950d9f40 397 Gene3D G3DSA:3.40.50.300 77 205 3.0E-32 T 29-03-2018 SMALA_RS22515 11da00683a243ddb744f2db7950d9f40 397 Gene3D G3DSA:2.40.30.10 208 302 3.0E-30 T 29-03-2018 SMALA_RS22515 11da00683a243ddb744f2db7950d9f40 397 SUPERFAMILY SSF50447 207 304 1.02E-30 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain SMALA_RS22515 11da00683a243ddb744f2db7950d9f40 397 Pfam PF03143 Elongation factor Tu C-terminal domain 301 395 1.1E-33 T 29-03-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal SMALA_RS22515 11da00683a243ddb744f2db7950d9f40 397 Gene3D G3DSA:2.40.30.10 303 396 2.3E-33 T 29-03-2018 SMALA_RS22515 11da00683a243ddb744f2db7950d9f40 397 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 397 59.588 T 29-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SMALA_RS22515 11da00683a243ddb744f2db7950d9f40 397 Gene3D G3DSA:3.40.50.300 2 76 1.1E-11 T 29-03-2018 SMALA_RS22515 11da00683a243ddb744f2db7950d9f40 397 SUPERFAMILY SSF52540 6 221 6.59E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS22515 11da00683a243ddb744f2db7950d9f40 397 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 147 1.9E-13 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 SMALA_RS22515 11da00683a243ddb744f2db7950d9f40 397 Pfam PF03144 Elongation factor Tu domain 2 227 296 7.6E-17 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 SMALA_RS22515 11da00683a243ddb744f2db7950d9f40 397 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 2 397 5.4E-223 T 29-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SMALA_RS22515 11da00683a243ddb744f2db7950d9f40 397 PRINTS PR00315 GTP-binding elongation factor signature 133 142 2.3E-24 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMALA_RS22515 11da00683a243ddb744f2db7950d9f40 397 PRINTS PR00315 GTP-binding elongation factor signature 60 68 2.3E-24 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMALA_RS22515 11da00683a243ddb744f2db7950d9f40 397 PRINTS PR00315 GTP-binding elongation factor signature 96 107 2.3E-24 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMALA_RS22515 11da00683a243ddb744f2db7950d9f40 397 PRINTS PR00315 GTP-binding elongation factor signature 14 27 2.3E-24 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMALA_RS22515 11da00683a243ddb744f2db7950d9f40 397 PRINTS PR00315 GTP-binding elongation factor signature 80 90 2.3E-24 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMALA_RS22515 11da00683a243ddb744f2db7950d9f40 397 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 4.5E-59 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMALA_RS25470 d8019b6570d5ccd5e8345f07541ff68f 235 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 160 180 3.6E-7 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMALA_RS25470 d8019b6570d5ccd5e8345f07541ff68f 235 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 110 123 3.6E-7 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMALA_RS25470 d8019b6570d5ccd5e8345f07541ff68f 235 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 16 27 3.6E-7 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMALA_RS25470 d8019b6570d5ccd5e8345f07541ff68f 235 Gene3D G3DSA:3.40.50.1000 7 223 3.1E-33 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS25470 d8019b6570d5ccd5e8345f07541ff68f 235 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 147 198 3.0E-12 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMALA_RS25470 d8019b6570d5ccd5e8345f07541ff68f 235 SUPERFAMILY SSF56784 15 220 2.58E-41 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS25470 d8019b6570d5ccd5e8345f07541ff68f 235 Pfam PF13419 Haloacid dehalogenase-like hydrolase 19 198 2.1E-21 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS02490 fec5aef0229a6549f4c8b3c9d3f21df2 284 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 2.8E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS02490 fec5aef0229a6549f4c8b3c9d3f21df2 284 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 2.8E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS02490 fec5aef0229a6549f4c8b3c9d3f21df2 284 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 2.8E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS02490 fec5aef0229a6549f4c8b3c9d3f21df2 284 Gene3D G3DSA:1.10.10.10 1 84 8.1E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS02490 fec5aef0229a6549f4c8b3c9d3f21df2 284 SUPERFAMILY SSF46785 4 84 1.07E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS02490 fec5aef0229a6549f4c8b3c9d3f21df2 284 SUPERFAMILY SSF53850 90 282 7.6E-22 T 29-03-2018 SMALA_RS02490 fec5aef0229a6549f4c8b3c9d3f21df2 284 Gene3D G3DSA:3.40.190.10 86 172 4.8E-18 T 29-03-2018 SMALA_RS02490 fec5aef0229a6549f4c8b3c9d3f21df2 284 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 2.5E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS02490 fec5aef0229a6549f4c8b3c9d3f21df2 284 Pfam PF03466 LysR substrate binding domain 89 279 8.5E-21 T 29-03-2018 IPR005119 LysR, substrate-binding SMALA_RS02490 fec5aef0229a6549f4c8b3c9d3f21df2 284 Gene3D G3DSA:3.40.190.10 173 254 2.8E-10 T 29-03-2018 SMALA_RS39970 f788cfa49ec42e5ce40b403c351ffa25 368 Gene3D G3DSA:3.90.180.10 1 179 1.1E-39 T 29-03-2018 SMALA_RS39970 f788cfa49ec42e5ce40b403c351ffa25 368 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 140 4.7E-22 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS39970 f788cfa49ec42e5ce40b403c351ffa25 368 SUPERFAMILY SSF50129 337 357 1.98E-40 T 29-03-2018 IPR011032 GroES-like SMALA_RS39970 f788cfa49ec42e5ce40b403c351ffa25 368 SUPERFAMILY SSF50129 2 155 1.98E-40 T 29-03-2018 IPR011032 GroES-like SMALA_RS39970 f788cfa49ec42e5ce40b403c351ffa25 368 Pfam PF00107 Zinc-binding dehydrogenase 189 322 2.6E-8 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMALA_RS39970 f788cfa49ec42e5ce40b403c351ffa25 368 SUPERFAMILY SSF51735 170 344 3.38E-17 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS39970 f788cfa49ec42e5ce40b403c351ffa25 368 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 61 75 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 SMALA_RS39970 f788cfa49ec42e5ce40b403c351ffa25 368 Gene3D G3DSA:3.40.50.720 180 312 5.0E-14 T 29-03-2018 SMALA_RS06505 c213fe122695a302989b75e25d02d36e 331 Gene3D G3DSA:3.40.50.720 153 264 1.7E-13 T 29-03-2018 SMALA_RS06505 c213fe122695a302989b75e25d02d36e 331 SUPERFAMILY SSF51735 116 271 1.25E-27 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS06505 c213fe122695a302989b75e25d02d36e 331 Pfam PF13602 Zinc-binding dehydrogenase 191 329 1.1E-10 T 29-03-2018 SMALA_RS06505 c213fe122695a302989b75e25d02d36e 331 SMART SM00829 10 329 3.5E-13 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS06505 c213fe122695a302989b75e25d02d36e 331 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 30 88 1.6E-6 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS06505 c213fe122695a302989b75e25d02d36e 331 Gene3D G3DSA:3.90.180.10 1 152 9.0E-44 T 29-03-2018 SMALA_RS06505 c213fe122695a302989b75e25d02d36e 331 SUPERFAMILY SSF50129 1 137 8.07E-32 T 29-03-2018 IPR011032 GroES-like SMALA_RS01935 892e7eddc899bb2c37dec818f4637d0e 259 SMART SM00382 33 214 1.4E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS01935 892e7eddc899bb2c37dec818f4637d0e 259 Pfam PF00005 ABC transporter 25 163 9.9E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS01935 892e7eddc899bb2c37dec818f4637d0e 259 Gene3D G3DSA:3.40.50.300 1 223 4.8E-64 T 29-03-2018 SMALA_RS01935 892e7eddc899bb2c37dec818f4637d0e 259 SUPERFAMILY SSF52540 5 232 4.51E-71 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS20505 28130a82076a6aef5af373dce4ecd889 270 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 32 260 1.6E-59 T 29-03-2018 SMALA_RS20505 28130a82076a6aef5af373dce4ecd889 270 SUPERFAMILY SSF51735 21 260 9.59E-75 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS20505 28130a82076a6aef5af373dce4ecd889 270 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 156 3.4E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS20505 28130a82076a6aef5af373dce4ecd889 270 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 95 106 3.4E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS20505 28130a82076a6aef5af373dce4ecd889 270 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 168 187 3.4E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS20505 28130a82076a6aef5af373dce4ecd889 270 Gene3D G3DSA:3.40.50.720 1 267 4.7E-68 T 29-03-2018 SMALA_RS20505 28130a82076a6aef5af373dce4ecd889 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 142 158 4.1E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS20505 28130a82076a6aef5af373dce4ecd889 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 187 4.1E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS20505 28130a82076a6aef5af373dce4ecd889 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 189 206 4.1E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS20505 28130a82076a6aef5af373dce4ecd889 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 95 106 4.1E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS20505 28130a82076a6aef5af373dce4ecd889 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 24 41 4.1E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS20505 28130a82076a6aef5af373dce4ecd889 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 224 244 4.1E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS20135 fea0859a8a595274fec2bd1f5c6c9e68 447 SUPERFAMILY SSF51126 282 343 3.61E-33 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor SMALA_RS20135 fea0859a8a595274fec2bd1f5c6c9e68 447 SUPERFAMILY SSF51126 49 251 3.61E-33 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor SMALA_RS20135 fea0859a8a595274fec2bd1f5c6c9e68 447 Pfam PF13229 Right handed beta helix region 161 324 1.8E-13 T 29-03-2018 SMALA_RS20135 fea0859a8a595274fec2bd1f5c6c9e68 447 Gene3D G3DSA:2.160.20.10 22 429 2.0E-41 T 29-03-2018 IPR012334 Pectin lyase fold SMALA_RS20135 fea0859a8a595274fec2bd1f5c6c9e68 447 SMART SM00710 109 131 2.2 T 29-03-2018 IPR006626 Parallel beta-helix repeat SMALA_RS20135 fea0859a8a595274fec2bd1f5c6c9e68 447 SMART SM00710 257 291 2300.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat SMALA_RS20135 fea0859a8a595274fec2bd1f5c6c9e68 447 SMART SM00710 179 201 22.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat SMALA_RS20135 fea0859a8a595274fec2bd1f5c6c9e68 447 SMART SM00710 227 248 1600.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat SMALA_RS20135 fea0859a8a595274fec2bd1f5c6c9e68 447 SMART SM00710 292 314 18.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat SMALA_RS20135 fea0859a8a595274fec2bd1f5c6c9e68 447 SMART SM00710 320 354 7900.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat SMALA_RS20135 fea0859a8a595274fec2bd1f5c6c9e68 447 SMART SM00710 156 178 1900.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat SMALA_RS03985 9ade5a632cf419bbea1315668137ff29 344 SUPERFAMILY SSF52540 2 184 8.18E-21 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS03985 9ade5a632cf419bbea1315668137ff29 344 Gene3D G3DSA:3.90.79.10 189 341 1.7E-21 T 29-03-2018 SMALA_RS03985 9ade5a632cf419bbea1315668137ff29 344 SUPERFAMILY SSF55811 185 329 1.1E-20 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMALA_RS03985 9ade5a632cf419bbea1315668137ff29 344 PRINTS PR00502 NUDIX hydrolase family signature 224 238 5.0E-5 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMALA_RS03985 9ade5a632cf419bbea1315668137ff29 344 PRINTS PR00502 NUDIX hydrolase family signature 238 253 5.0E-5 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMALA_RS03985 9ade5a632cf419bbea1315668137ff29 344 Pfam PF00293 NUDIX domain 200 314 4.7E-14 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SMALA_RS03985 9ade5a632cf419bbea1315668137ff29 344 Pfam PF13671 AAA domain 3 143 1.0E-9 T 29-03-2018 SMALA_RS03985 9ade5a632cf419bbea1315668137ff29 344 Gene3D G3DSA:3.40.50.300 1 188 4.1E-25 T 29-03-2018 SMALA_RS11575 6174f5fe2f8d37b742f0288d35981bb4 305 SUPERFAMILY SSF46689 200 251 1.11E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS11575 6174f5fe2f8d37b742f0288d35981bb4 305 Gene3D G3DSA:1.10.10.60 198 258 3.2E-8 T 29-03-2018 SMALA_RS11575 6174f5fe2f8d37b742f0288d35981bb4 305 Gene3D G3DSA:1.10.10.60 259 305 1.6E-13 T 29-03-2018 SMALA_RS11575 6174f5fe2f8d37b742f0288d35981bb4 305 Pfam PF12852 Cupin 2 184 4.1E-35 T 29-03-2018 IPR032783 AraC-type transcription regulator, ligand-binding domain SMALA_RS11575 6174f5fe2f8d37b742f0288d35981bb4 305 Gene3D G3DSA:2.60.120.280 30 184 2.8E-16 T 29-03-2018 SMALA_RS11575 6174f5fe2f8d37b742f0288d35981bb4 305 SMART SM00342 217 300 5.4E-30 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS11575 6174f5fe2f8d37b742f0288d35981bb4 305 SUPERFAMILY SSF51182 19 75 4.89E-5 T 29-03-2018 IPR011051 RmlC-like cupin domain SMALA_RS11575 6174f5fe2f8d37b742f0288d35981bb4 305 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 254 296 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 SMALA_RS11575 6174f5fe2f8d37b742f0288d35981bb4 305 SUPERFAMILY SSF46689 253 303 4.44E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS11575 6174f5fe2f8d37b742f0288d35981bb4 305 Pfam PF12833 Helix-turn-helix domain 223 302 5.7E-22 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS11575 6174f5fe2f8d37b742f0288d35981bb4 305 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 284 300 2.9E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SMALA_RS11575 6174f5fe2f8d37b742f0288d35981bb4 305 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 269 284 2.9E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SMALA_RS13580 b5715cc71c238543794e7dbdeea2469b 156 Pfam PF02080 TrkA-C domain 85 154 3.4E-14 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 SMALA_RS13580 b5715cc71c238543794e7dbdeea2469b 156 Gene3D G3DSA:3.30.70.1450 72 156 1.0E-15 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 SMALA_RS13580 b5715cc71c238543794e7dbdeea2469b 156 PIRSF PIRSF005028 1 156 2.9E-52 T 29-03-2018 IPR026278 Potassium/proton antiporter subunit KhtT SMALA_RS13580 b5715cc71c238543794e7dbdeea2469b 156 SUPERFAMILY SSF116726 79 154 9.29E-16 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 SMALA_RS28865 0315920bbc90642e0caff381ef50d69b 478 SMART SM00388 252 315 1.7E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS28865 0315920bbc90642e0caff381ef50d69b 478 SUPERFAMILY SSF55874 304 466 2.62E-33 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS28865 0315920bbc90642e0caff381ef50d69b 478 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 359 466 2.3E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS28865 0315920bbc90642e0caff381ef50d69b 478 Gene3D G3DSA:3.30.565.10 296 467 2.0E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS28865 0315920bbc90642e0caff381ef50d69b 478 PRINTS PR00344 Bacterial sensor protein C-terminal signature 395 409 1.4E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS28865 0315920bbc90642e0caff381ef50d69b 478 PRINTS PR00344 Bacterial sensor protein C-terminal signature 428 446 1.4E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS28865 0315920bbc90642e0caff381ef50d69b 478 PRINTS PR00344 Bacterial sensor protein C-terminal signature 452 465 1.4E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS28865 0315920bbc90642e0caff381ef50d69b 478 Pfam PF00512 His Kinase A (phospho-acceptor) domain 253 313 1.6E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS28865 0315920bbc90642e0caff381ef50d69b 478 SUPERFAMILY SSF158472 199 249 2.22E-7 T 29-03-2018 SMALA_RS28865 0315920bbc90642e0caff381ef50d69b 478 SMART SM00304 198 251 9.8E-10 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMALA_RS28865 0315920bbc90642e0caff381ef50d69b 478 SUPERFAMILY SSF47384 235 313 5.69E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS28865 0315920bbc90642e0caff381ef50d69b 478 Pfam PF00672 HAMP domain 199 247 3.9E-7 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMALA_RS28865 0315920bbc90642e0caff381ef50d69b 478 Gene3D G3DSA:1.10.287.130 242 295 3.6E-13 T 29-03-2018 SMALA_RS28865 0315920bbc90642e0caff381ef50d69b 478 SMART SM00387 358 468 1.1E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS38745 225357f53d95a44c0826af4e258da4fd 390 Pfam PF01266 FAD dependent oxidoreductase 14 358 2.1E-65 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 SMALA_RS38745 225357f53d95a44c0826af4e258da4fd 390 SUPERFAMILY SSF51905 320 382 1.34E-58 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS38745 225357f53d95a44c0826af4e258da4fd 390 SUPERFAMILY SSF51905 13 228 1.34E-58 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS38745 225357f53d95a44c0826af4e258da4fd 390 Gene3D G3DSA:3.50.50.60 2 91 1.7E-6 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS38745 225357f53d95a44c0826af4e258da4fd 390 SUPERFAMILY SSF54373 228 319 3.63E-5 T 29-03-2018 SMALA_RS38745 225357f53d95a44c0826af4e258da4fd 390 Gene3D G3DSA:3.30.9.10 168 319 2.5E-42 T 29-03-2018 SMALA_RS38745 225357f53d95a44c0826af4e258da4fd 390 Gene3D G3DSA:3.30.9.10 95 167 6.2E-9 T 29-03-2018 SMALA_RS01995 461af23e8b300a1a7424e535a4ae1f12 260 Gene3D G3DSA:3.20.20.150 2 259 6.5E-45 T 29-03-2018 SMALA_RS01995 461af23e8b300a1a7424e535a4ae1f12 260 SUPERFAMILY SSF51658 1 257 1.44E-55 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SMALA_RS01995 461af23e8b300a1a7424e535a4ae1f12 260 Pfam PF01261 Xylose isomerase-like TIM barrel 42 219 3.2E-21 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SMALA_RS01995 461af23e8b300a1a7424e535a4ae1f12 260 PIRSF PIRSF006241 1 259 1.2E-56 T 29-03-2018 IPR026040 Hydroxypyruvate isomerase-like KEGG: 00630+5.3.1.22 SMALA_RS28175 158a78705c29596f631616704dcb519c 255 SUPERFAMILY SSF51306 42 191 7.85E-40 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C SMALA_RS28175 158a78705c29596f631616704dcb519c 255 Gene3D G3DSA:2.10.109.10 38 198 4.6E-34 T 29-03-2018 SMALA_RS28175 158a78705c29596f631616704dcb519c 255 Pfam PF00717 Peptidase S24-like 47 117 1.7E-14 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C SMALA_RS28175 158a78705c29596f631616704dcb519c 255 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 28 185 1.8E-37 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SMALA_RS28175 158a78705c29596f631616704dcb519c 255 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 41 57 4.9E-19 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SMALA_RS28175 158a78705c29596f631616704dcb519c 255 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 91 103 4.9E-19 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SMALA_RS28175 158a78705c29596f631616704dcb519c 255 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 139 158 4.9E-19 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SMALA_RS15760 de60fe0bcc6d9f0ff2dfa8eefed68444 492 Gene3D G3DSA:3.40.50.300 193 367 3.4E-4 T 29-03-2018 SMALA_RS15760 de60fe0bcc6d9f0ff2dfa8eefed68444 492 SUPERFAMILY SSF52540 191 327 3.69E-5 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS28675 8f7a900552a841ff2333e3c510a93941 246 Pfam PF02511 Thymidylate synthase complementing protein 20 232 2.4E-49 T 29-03-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 SMALA_RS28675 8f7a900552a841ff2333e3c510a93941 246 TIGRFAM TIGR02170 thyX: thymidylate synthase, flavin-dependent 19 238 6.2E-61 T 29-03-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 SMALA_RS28675 8f7a900552a841ff2333e3c510a93941 246 SUPERFAMILY SSF69796 11 239 1.14E-52 T 29-03-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 SMALA_RS28675 8f7a900552a841ff2333e3c510a93941 246 Gene3D G3DSA:1.10.357.10 87 232 3.9E-4 T 29-03-2018 SMALA_RS28675 8f7a900552a841ff2333e3c510a93941 246 Hamap MF_01408 Flavin-dependent thymidylate synthase [thyX]. 15 246 27.448 T 29-03-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 SMALA_RS25090 647a2a64869a0e425bb89726604fa5ba 312 Pfam PF12833 Helix-turn-helix domain 229 308 5.7E-21 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS25090 647a2a64869a0e425bb89726604fa5ba 312 Pfam PF12852 Cupin 2 192 1.8E-49 T 29-03-2018 IPR032783 AraC-type transcription regulator, ligand-binding domain SMALA_RS25090 647a2a64869a0e425bb89726604fa5ba 312 Gene3D G3DSA:1.10.10.60 264 311 2.8E-10 T 29-03-2018 SMALA_RS25090 647a2a64869a0e425bb89726604fa5ba 312 SUPERFAMILY SSF46689 206 257 2.42E-7 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS25090 647a2a64869a0e425bb89726604fa5ba 312 SMART SM00342 223 307 1.4E-29 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS25090 647a2a64869a0e425bb89726604fa5ba 312 SUPERFAMILY SSF46689 259 308 3.85E-9 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS25090 647a2a64869a0e425bb89726604fa5ba 312 Gene3D G3DSA:1.10.10.60 133 263 1.2E-11 T 29-03-2018 SMALA_RS38850 348f8dba997c7b9a09dccd6f010819e1 442 Gene3D G3DSA:1.25.10.10 155 439 1.9E-4 T 29-03-2018 IPR011989 Armadillo-like helical SMALA_RS38850 348f8dba997c7b9a09dccd6f010819e1 442 Gene3D G3DSA:1.25.40.70 9 154 0.0012 T 29-03-2018 SMALA_RS38850 348f8dba997c7b9a09dccd6f010819e1 442 SMART SM00567 E-Z type HEAT repeats 149 175 1000.0 T 29-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 SMALA_RS38850 348f8dba997c7b9a09dccd6f010819e1 442 SMART SM00567 E-Z type HEAT repeats 24 52 120.0 T 29-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 SMALA_RS38850 348f8dba997c7b9a09dccd6f010819e1 442 SMART SM00567 E-Z type HEAT repeats 115 144 0.28 T 29-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 SMALA_RS21620 6dbc3489493d000031a48d666dab5257 506 PRINTS PR01036 Tetracycline resistance protein TetB signature 5 29 1.0E-10 T 29-03-2018 SMALA_RS21620 6dbc3489493d000031a48d666dab5257 506 PRINTS PR01036 Tetracycline resistance protein TetB signature 95 115 1.0E-10 T 29-03-2018 SMALA_RS21620 6dbc3489493d000031a48d666dab5257 506 PRINTS PR01036 Tetracycline resistance protein TetB signature 389 408 1.0E-10 T 29-03-2018 SMALA_RS21620 6dbc3489493d000031a48d666dab5257 506 PRINTS PR01036 Tetracycline resistance protein TetB signature 125 149 1.0E-10 T 29-03-2018 SMALA_RS21620 6dbc3489493d000031a48d666dab5257 506 PRINTS PR01036 Tetracycline resistance protein TetB signature 190 208 1.0E-10 T 29-03-2018 SMALA_RS21620 6dbc3489493d000031a48d666dab5257 506 Gene3D G3DSA:1.20.1250.20 1 189 1.1E-37 T 29-03-2018 SMALA_RS21620 6dbc3489493d000031a48d666dab5257 506 Gene3D G3DSA:1.20.1250.20 240 488 3.5E-33 T 29-03-2018 SMALA_RS21620 6dbc3489493d000031a48d666dab5257 506 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 2 476 6.4E-83 T 29-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 SMALA_RS21620 6dbc3489493d000031a48d666dab5257 506 Pfam PF07690 Major Facilitator Superfamily 6 398 9.7E-54 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS21620 6dbc3489493d000031a48d666dab5257 506 SUPERFAMILY SSF103473 236 408 1.07E-70 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS21620 6dbc3489493d000031a48d666dab5257 506 SUPERFAMILY SSF103473 2 183 1.07E-70 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS21620 6dbc3489493d000031a48d666dab5257 506 SUPERFAMILY SSF103473 454 478 1.07E-70 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS25585 3d64d0bed7e6d571ca730c1863d09ddb 352 Gene3D G3DSA:3.40.50.300 20 348 5.9E-78 T 29-03-2018 SMALA_RS25585 3d64d0bed7e6d571ca730c1863d09ddb 352 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 252 332 9.2E-28 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMALA_RS25585 3d64d0bed7e6d571ca730c1863d09ddb 352 Pfam PF00005 ABC transporter 44 202 1.7E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS25585 3d64d0bed7e6d571ca730c1863d09ddb 352 SUPERFAMILY SSF52540 53 327 2.61E-68 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS25585 3d64d0bed7e6d571ca730c1863d09ddb 352 ProSitePatterns PS00211 ABC transporters family signature. 175 189 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS25585 3d64d0bed7e6d571ca730c1863d09ddb 352 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 254 318 9.3E-22 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMALA_RS25585 3d64d0bed7e6d571ca730c1863d09ddb 352 SMART SM00382 52 252 1.4E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS05240 352daecbf2228d8c5f14bd7e14ad84be 248 Gene3D G3DSA:2.130.10.130 18 202 8.7E-7 T 29-03-2018 SMALA_RS05240 352daecbf2228d8c5f14bd7e14ad84be 248 SUPERFAMILY SSF69318 54 196 4.19E-9 T 29-03-2018 SMALA_RS05240 352daecbf2228d8c5f14bd7e14ad84be 248 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 61 127 4.5E-7 T 29-03-2018 SMALA_RS35215 c9cb4d0af72d5ced3238955c4d12857a 221 Pfam PF00571 CBS domain 91 143 3.6E-17 T 29-03-2018 IPR000644 CBS domain SMALA_RS35215 c9cb4d0af72d5ced3238955c4d12857a 221 Pfam PF00571 CBS domain 8 59 1.8E-10 T 29-03-2018 IPR000644 CBS domain SMALA_RS35215 c9cb4d0af72d5ced3238955c4d12857a 221 Pfam PF04972 BON domain 147 214 4.6E-12 T 29-03-2018 IPR007055 BON domain SMALA_RS35215 c9cb4d0af72d5ced3238955c4d12857a 221 Gene3D G3DSA:3.10.580.10 84 206 7.4E-19 T 29-03-2018 SMALA_RS35215 c9cb4d0af72d5ced3238955c4d12857a 221 PIRSF PIRSF036990 6 221 6.3E-67 T 29-03-2018 IPR017080 Uncharacterised conserved protein UCP036990, CBS, BON SMALA_RS35215 c9cb4d0af72d5ced3238955c4d12857a 221 Gene3D G3DSA:3.10.580.10 4 83 1.4E-11 T 29-03-2018 SMALA_RS35215 c9cb4d0af72d5ced3238955c4d12857a 221 SUPERFAMILY SSF54631 6 147 8.59E-34 T 29-03-2018 SMALA_RS35215 c9cb4d0af72d5ced3238955c4d12857a 221 SMART SM00116 15 63 0.037 T 29-03-2018 IPR000644 CBS domain SMALA_RS35215 c9cb4d0af72d5ced3238955c4d12857a 221 SMART SM00116 96 144 1.7E-12 T 29-03-2018 IPR000644 CBS domain SMALA_RS32515 ac532cd1e305004497edb39b87fafcaa 329 Gene3D G3DSA:3.20.20.100 7 328 3.9E-42 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS32515 ac532cd1e305004497edb39b87fafcaa 329 Pfam PF00248 Aldo/keto reductase family 49 313 1.3E-29 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS32515 ac532cd1e305004497edb39b87fafcaa 329 SUPERFAMILY SSF51430 51 313 9.95E-40 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS40320 8b4ed04d74d16d37550466baeda24556 493 SUPERFAMILY SSF143243 4 155 1.16E-27 T 29-03-2018 SMALA_RS40320 8b4ed04d74d16d37550466baeda24556 493 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 254 414 2.1E-23 T 29-03-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS40320 8b4ed04d74d16d37550466baeda24556 493 Gene3D G3DSA:1.10.645.10 137 314 6.2E-40 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS40320 8b4ed04d74d16d37550466baeda24556 493 Gene3D G3DSA:1.10.645.10 327 489 1.5E-24 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS40320 8b4ed04d74d16d37550466baeda24556 493 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 9 117 2.5E-13 T 29-03-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS40320 8b4ed04d74d16d37550466baeda24556 493 ProSitePatterns PS00542 Respiratory chain NADH dehydrogenase 30 Kd subunit signature. 80 101 - T 29-03-2018 IPR020396 NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS40320 8b4ed04d74d16d37550466baeda24556 493 SUPERFAMILY SSF56762 151 492 1.57E-81 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS40320 8b4ed04d74d16d37550466baeda24556 493 Pfam PF00374 Nickel-dependent hydrogenase 179 246 1.9E-6 T 29-03-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 SMALA_RS40320 8b4ed04d74d16d37550466baeda24556 493 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 64 116 2.0E-15 T 29-03-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS06630 4f0a7d493181bba6726c616540db73ff 609 Pfam PF00501 AMP-binding enzyme 18 480 4.5E-77 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS06630 4f0a7d493181bba6726c616540db73ff 609 Gene3D G3DSA:2.30.38.10 388 472 7.2E-15 T 29-03-2018 SMALA_RS06630 4f0a7d493181bba6726c616540db73ff 609 Gene3D G3DSA:3.40.50.980 8 197 2.2E-37 T 29-03-2018 SMALA_RS06630 4f0a7d493181bba6726c616540db73ff 609 SUPERFAMILY SSF56801 347 594 2.88E-102 T 29-03-2018 SMALA_RS06630 4f0a7d493181bba6726c616540db73ff 609 SUPERFAMILY SSF56801 9 295 2.88E-102 T 29-03-2018 SMALA_RS06630 4f0a7d493181bba6726c616540db73ff 609 Gene3D G3DSA:3.40.50.980 198 387 7.4E-28 T 29-03-2018 SMALA_RS06630 4f0a7d493181bba6726c616540db73ff 609 Gene3D G3DSA:3.30.300.30 474 594 1.4E-17 T 29-03-2018 SMALA_RS06630 4f0a7d493181bba6726c616540db73ff 609 ProSitePatterns PS00455 Putative AMP-binding domain signature. 191 202 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS06275 2c1154b9e0f970c94eb4d9340579a344 511 Gene3D G3DSA:3.40.50.1820 27 497 1.9E-38 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS06275 2c1154b9e0f970c94eb4d9340579a344 511 SUPERFAMILY SSF53474 53 142 4.78E-23 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS06275 2c1154b9e0f970c94eb4d9340579a344 511 SUPERFAMILY SSF53474 187 483 4.78E-23 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS06275 2c1154b9e0f970c94eb4d9340579a344 511 Pfam PF00561 alpha/beta hydrolase fold 93 480 6.6E-23 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS40480 3d5c603c8e239c58b3544ffd4ec52847 265 Pfam PF12833 Helix-turn-helix domain 176 251 1.8E-16 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS40480 3d5c603c8e239c58b3544ffd4ec52847 265 Gene3D G3DSA:2.60.120.10 14 140 1.4E-8 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SMALA_RS40480 3d5c603c8e239c58b3544ffd4ec52847 265 SMART SM00342 170 251 7.3E-14 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS40480 3d5c603c8e239c58b3544ffd4ec52847 265 SUPERFAMILY SSF51182 22 169 6.9E-14 T 29-03-2018 IPR011051 RmlC-like cupin domain SMALA_RS40480 3d5c603c8e239c58b3544ffd4ec52847 265 SUPERFAMILY SSF46689 207 252 8.51E-7 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS40480 3d5c603c8e239c58b3544ffd4ec52847 265 Pfam PF02311 AraC-like ligand binding domain 24 109 1.3E-5 T 29-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 SMALA_RS40480 3d5c603c8e239c58b3544ffd4ec52847 265 Gene3D G3DSA:1.10.10.60 210 262 2.0E-9 T 29-03-2018 SMALA_RS40480 3d5c603c8e239c58b3544ffd4ec52847 265 Gene3D G3DSA:1.10.10.60 156 209 6.1E-7 T 29-03-2018 SMALA_RS36080 deba7f5410865a786b0dd42478b3e947 153 SUPERFAMILY SSF52402 19 153 2.6E-24 T 29-03-2018 SMALA_RS36080 deba7f5410865a786b0dd42478b3e947 153 Gene3D G3DSA:3.40.50.620 8 153 3.2E-26 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS36080 deba7f5410865a786b0dd42478b3e947 153 PRINTS PR01438 Universal stress protein signature 131 153 3.2E-6 T 29-03-2018 IPR006015 Universal stress protein A SMALA_RS36080 deba7f5410865a786b0dd42478b3e947 153 PRINTS PR01438 Universal stress protein signature 16 34 3.2E-6 T 29-03-2018 IPR006015 Universal stress protein A SMALA_RS36080 deba7f5410865a786b0dd42478b3e947 153 Pfam PF00582 Universal stress protein family 17 153 6.1E-23 T 29-03-2018 IPR006016 UspA GO:0006950 SMALA_RS34485 2308acd43e9090e8261f66d969d23c86 222 Gene3D G3DSA:3.40.50.720 2 194 2.4E-21 T 29-03-2018 SMALA_RS34485 2308acd43e9090e8261f66d969d23c86 222 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 7 95 2.2E-15 T 29-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal SMALA_RS34485 2308acd43e9090e8261f66d969d23c86 222 SUPERFAMILY SSF51735 7 201 3.71E-30 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS22595 3eb747fa18a3b054045cf04b94292767 186 PIRSF PIRSF002161 3 186 4.5E-65 T 29-03-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMALA_RS22595 3eb747fa18a3b054045cf04b94292767 186 SUPERFAMILY SSF55282 9 184 1.3E-75 T 29-03-2018 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMALA_RS22595 3eb747fa18a3b054045cf04b94292767 186 Pfam PF00281 Ribosomal protein L5 30 86 3.2E-28 T 29-03-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMALA_RS22595 3eb747fa18a3b054045cf04b94292767 186 Pfam PF00673 ribosomal L5P family C-terminus 90 183 9.1E-40 T 29-03-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMALA_RS22595 3eb747fa18a3b054045cf04b94292767 186 Gene3D G3DSA:3.30.1440.10 7 185 1.5E-75 T 29-03-2018 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMALA_RS22595 3eb747fa18a3b054045cf04b94292767 186 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 7 185 43.769 T 29-03-2018 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS22595 3eb747fa18a3b054045cf04b94292767 186 ProSitePatterns PS00358 Ribosomal protein L5 signature. 63 79 - T 29-03-2018 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMALA_RS16105 cb2f69be861943bf701778d7aa32bbaa 488 PRINTS PR00173 Glutamate-aspartate symporter signature 144 169 8.0E-5 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SMALA_RS16105 cb2f69be861943bf701778d7aa32bbaa 488 PRINTS PR00173 Glutamate-aspartate symporter signature 62 82 8.0E-5 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SMALA_RS16105 cb2f69be861943bf701778d7aa32bbaa 488 PRINTS PR00173 Glutamate-aspartate symporter signature 280 299 8.0E-5 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SMALA_RS16105 cb2f69be861943bf701778d7aa32bbaa 488 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 26 448 7.5E-56 T 29-03-2018 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 SMALA_RS16105 cb2f69be861943bf701778d7aa32bbaa 488 PIRSF PIRSF002744 3 471 2.9E-103 T 29-03-2018 IPR026030 Purine-cytosine permease Fcy2/21/22 GO:0005215|GO:0016021|GO:0055085 SMALA_RS13120 0c81768bac999195c65b24d50c3db627 477 ProSitePatterns PS00905 GTP1/OBG family signature. 212 225 - T 29-03-2018 IPR006074 GTP1/OBG, conserved site GO:0005525 SMALA_RS13120 0c81768bac999195c65b24d50c3db627 477 Gene3D G3DSA:2.70.210.12 3 156 7.1E-50 T 29-03-2018 IPR006169 GTP1/OBG domain SMALA_RS13120 0c81768bac999195c65b24d50c3db627 477 Gene3D G3DSA:3.40.50.300 159 341 8.0E-28 T 29-03-2018 SMALA_RS13120 0c81768bac999195c65b24d50c3db627 477 SUPERFAMILY SSF82051 4 157 6.93E-46 T 29-03-2018 IPR006169 GTP1/OBG domain SMALA_RS13120 0c81768bac999195c65b24d50c3db627 477 SUPERFAMILY SSF102741 356 429 2.62E-18 T 29-03-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 SMALA_RS13120 0c81768bac999195c65b24d50c3db627 477 Hamap MF_01454 GTPase Obg [obg]. 3 330 43.302 T 29-03-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 SMALA_RS13120 0c81768bac999195c65b24d50c3db627 477 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 162 182 3.9E-35 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 SMALA_RS13120 0c81768bac999195c65b24d50c3db627 477 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 227 245 3.9E-35 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 SMALA_RS13120 0c81768bac999195c65b24d50c3db627 477 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 183 201 3.9E-35 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 SMALA_RS13120 0c81768bac999195c65b24d50c3db627 477 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 210 225 3.9E-35 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 SMALA_RS13120 0c81768bac999195c65b24d50c3db627 477 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 4 329 2.1E-122 T 29-03-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 SMALA_RS13120 0c81768bac999195c65b24d50c3db627 477 SUPERFAMILY SSF52540 161 334 4.27E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS13120 0c81768bac999195c65b24d50c3db627 477 Pfam PF01018 GTP1/OBG 5 158 1.2E-50 T 29-03-2018 IPR006169 GTP1/OBG domain SMALA_RS13120 0c81768bac999195c65b24d50c3db627 477 Pfam PF01926 50S ribosome-binding GTPase 161 283 2.1E-22 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 SMALA_RS13120 0c81768bac999195c65b24d50c3db627 477 TIGRFAM TIGR03595 Obg_CgtA_exten: Obg family GTPase CgtA, C-terminal extension 358 428 3.2E-25 T 29-03-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 SMALA_RS13120 0c81768bac999195c65b24d50c3db627 477 Pfam PF09269 Domain of unknown function (DUF1967) 356 427 1.3E-23 T 29-03-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 SMALA_RS39830 5a46d5b3bd2c7a2303459e9aa061db27 514 SUPERFAMILY SSF75005 50 334 1.3E-43 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain SMALA_RS39830 5a46d5b3bd2c7a2303459e9aa061db27 514 Pfam PF04616 Glycosyl hydrolases family 43 51 275 5.1E-22 T 29-03-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 SMALA_RS39830 5a46d5b3bd2c7a2303459e9aa061db27 514 Gene3D G3DSA:2.115.10.20 12 351 2.0E-49 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain SMALA_RS33635 edc0238ef29d70fc59f5c59e7512957e 174 ProSitePatterns PS00893 Nudix box signature. 56 77 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 SMALA_RS33635 edc0238ef29d70fc59f5c59e7512957e 174 SUPERFAMILY SSF55811 10 162 8.67E-23 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMALA_RS33635 edc0238ef29d70fc59f5c59e7512957e 174 Gene3D G3DSA:3.90.79.10 1 172 1.7E-22 T 29-03-2018 SMALA_RS33635 edc0238ef29d70fc59f5c59e7512957e 174 PRINTS PR00502 NUDIX hydrolase family signature 51 65 7.6E-7 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMALA_RS33635 edc0238ef29d70fc59f5c59e7512957e 174 PRINTS PR00502 NUDIX hydrolase family signature 65 80 7.6E-7 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMALA_RS33635 edc0238ef29d70fc59f5c59e7512957e 174 Pfam PF00293 NUDIX domain 15 144 4.8E-19 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SMALA_RS02750 d0d83524d7414a128f047aba9d5f8c2e 304 SUPERFAMILY SSF50494 106 277 2.11E-17 T 29-03-2018 IPR009003 Peptidase S1, PA clan SMALA_RS02750 d0d83524d7414a128f047aba9d5f8c2e 304 Gene3D G3DSA:2.40.10.10 202 304 5.5E-21 T 29-03-2018 SMALA_RS02750 d0d83524d7414a128f047aba9d5f8c2e 304 Gene3D G3DSA:2.40.10.10 85 201 1.1E-10 T 29-03-2018 SMALA_RS14275 bd5d0bf6d1c2c1ea98da8de116904199 165 Gene3D G3DSA:3.30.530.20 7 165 2.7E-17 T 29-03-2018 IPR023393 START-like domain SMALA_RS14275 bd5d0bf6d1c2c1ea98da8de116904199 165 SUPERFAMILY SSF55961 16 159 1.51E-16 T 29-03-2018 SMALA_RS38455 c900454d41934c21bac95da5b53e5a95 966 SUPERFAMILY SSF56059 11 314 1.18E-74 T 29-03-2018 SMALA_RS38455 c900454d41934c21bac95da5b53e5a95 966 Gene3D G3DSA:3.30.1490.20 7 178 1.6E-40 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SMALA_RS38455 c900454d41934c21bac95da5b53e5a95 966 Pfam PF00391 PEP-utilising enzyme, mobile domain 817 885 4.2E-18 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 SMALA_RS38455 c900454d41934c21bac95da5b53e5a95 966 Gene3D G3DSA:3.50.30.10 792 902 3.7E-22 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 SMALA_RS38455 c900454d41934c21bac95da5b53e5a95 966 Gene3D G3DSA:3.30.470.20 179 323 1.6E-36 T 29-03-2018 SMALA_RS38455 c900454d41934c21bac95da5b53e5a95 966 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 15 314 3.7E-74 T 29-03-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 SMALA_RS38455 c900454d41934c21bac95da5b53e5a95 966 SUPERFAMILY SSF52009 792 888 4.71E-20 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 SMALA_RS35130 87c804399f0fb0b7044f6e3c389b16bd 343 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 48 334 1.8E-8 T 29-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 SMALA_RS35130 87c804399f0fb0b7044f6e3c389b16bd 343 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 126 303 9.8E-46 T 29-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 SMALA_RS35130 87c804399f0fb0b7044f6e3c389b16bd 343 SUPERFAMILY SSF52283 33 146 1.45E-12 T 29-03-2018 SMALA_RS35130 87c804399f0fb0b7044f6e3c389b16bd 343 Gene3D G3DSA:3.40.50.720 127 305 4.7E-44 T 29-03-2018 SMALA_RS35130 87c804399f0fb0b7044f6e3c389b16bd 343 Gene3D G3DSA:3.40.50.720 21 126 1.6E-18 T 29-03-2018 SMALA_RS35130 87c804399f0fb0b7044f6e3c389b16bd 343 SUPERFAMILY SSF51735 117 304 7.89E-43 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS35130 87c804399f0fb0b7044f6e3c389b16bd 343 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 214 236 - T 29-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site SMALA_RS41770 51085c22d540ff53e95cb2c169d2645b 301 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 88 1.8E-9 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS41770 51085c22d540ff53e95cb2c169d2645b 301 Pfam PF13602 Zinc-binding dehydrogenase 197 299 1.3E-13 T 29-03-2018 SMALA_RS41770 51085c22d540ff53e95cb2c169d2645b 301 Gene3D G3DSA:3.90.180.10 1 301 8.2E-61 T 29-03-2018 SMALA_RS41770 51085c22d540ff53e95cb2c169d2645b 301 SUPERFAMILY SSF51735 113 298 5.22E-23 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS41770 51085c22d540ff53e95cb2c169d2645b 301 SMART SM00829 10 299 2.2E-13 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS41770 51085c22d540ff53e95cb2c169d2645b 301 SUPERFAMILY SSF50129 1 147 1.11E-31 T 29-03-2018 IPR011032 GroES-like SMALA_RS14170 132ef47dfac17793a28fb3c3d113a9dd 266 Pfam PF15698 Phosphatase 13 262 1.2E-112 T 29-03-2018 IPR031423 Uncharacterised phosphatase SCO2771 SMALA_RS14170 132ef47dfac17793a28fb3c3d113a9dd 266 Gene3D G3DSA:3.40.50.2000 88 261 8.1E-6 T 29-03-2018 SMALA_RS34725 c1ee774b9112be164b961246aec555a3 234 Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. 1 206 24.648 T 29-03-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 SMALA_RS34725 c1ee774b9112be164b961246aec555a3 234 Pfam PF13500 AAA domain 4 201 4.0E-36 T 29-03-2018 SMALA_RS34725 c1ee774b9112be164b961246aec555a3 234 SUPERFAMILY SSF52540 1 203 1.55E-40 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS34725 c1ee774b9112be164b961246aec555a3 234 Gene3D G3DSA:3.40.50.300 1 209 3.7E-51 T 29-03-2018 SMALA_RS34725 c1ee774b9112be164b961246aec555a3 234 TIGRFAM TIGR00347 bioD: dethiobiotin synthase 6 169 6.6E-33 T 29-03-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 SMALA_RS34725 c1ee774b9112be164b961246aec555a3 234 PIRSF PIRSF006755 1 215 3.0E-39 T 29-03-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 SMALA_RS36175 a18627a5f268b5e252f226c2741e82f6 281 Gene3D G3DSA:3.40.30.10 32 170 1.6E-13 T 29-03-2018 SMALA_RS36175 a18627a5f268b5e252f226c2741e82f6 281 Pfam PF13410 Glutathione S-transferase, C-terminal domain 190 261 1.2E-10 T 29-03-2018 SMALA_RS36175 a18627a5f268b5e252f226c2741e82f6 281 SUPERFAMILY SSF47616 152 274 2.92E-16 T 29-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like SMALA_RS36175 a18627a5f268b5e252f226c2741e82f6 281 Gene3D G3DSA:1.20.1050.10 171 279 2.4E-18 T 29-03-2018 SMALA_RS40275 591a890c0ce6ea6682b5a99abd1c1128 211 Gene3D G3DSA:1.10.101.10 2 76 1.9E-13 T 29-03-2018 IPR002477 Peptidoglycan binding-like SMALA_RS40275 591a890c0ce6ea6682b5a99abd1c1128 211 SUPERFAMILY SSF47090 8 75 2.94E-11 T 29-03-2018 IPR002477 Peptidoglycan binding-like SMALA_RS40275 591a890c0ce6ea6682b5a99abd1c1128 211 SUPERFAMILY SSF51261 87 200 1.2E-33 T 29-03-2018 IPR011055 Duplicated hybrid motif SMALA_RS40275 591a890c0ce6ea6682b5a99abd1c1128 211 Pfam PF01471 Putative peptidoglycan binding domain 18 74 1.1E-7 T 29-03-2018 IPR002477 Peptidoglycan binding-like SMALA_RS40275 591a890c0ce6ea6682b5a99abd1c1128 211 Pfam PF01551 Peptidase family M23 110 198 6.4E-25 T 29-03-2018 IPR016047 Peptidase M23 SMALA_RS40275 591a890c0ce6ea6682b5a99abd1c1128 211 Gene3D G3DSA:2.70.70.10 77 209 9.8E-31 T 29-03-2018 SMALA_RS11230 f1854f3c7f18d6c36c332e48127bfc1a 326 SUPERFAMILY SSF49493 147 233 2.22E-16 T 29-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 SMALA_RS11230 f1854f3c7f18d6c36c332e48127bfc1a 326 Pfam PF00226 DnaJ domain 4 65 3.9E-25 T 29-03-2018 IPR001623 DnaJ domain SMALA_RS11230 f1854f3c7f18d6c36c332e48127bfc1a 326 Gene3D G3DSA:1.20.5.460 306 325 0.0014 T 29-03-2018 SMALA_RS11230 f1854f3c7f18d6c36c332e48127bfc1a 326 ProSitePatterns PS00636 Nt-dnaJ domain signature. 45 64 - T 29-03-2018 IPR018253 DnaJ domain, conserved site SMALA_RS11230 f1854f3c7f18d6c36c332e48127bfc1a 326 SUPERFAMILY SSF49493 226 311 2.49E-22 T 29-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 SMALA_RS11230 f1854f3c7f18d6c36c332e48127bfc1a 326 SMART SM00271 3 60 1.6E-28 T 29-03-2018 IPR001623 DnaJ domain SMALA_RS11230 f1854f3c7f18d6c36c332e48127bfc1a 326 PRINTS PR00625 DnaJ domain signature 6 24 1.5E-20 T 29-03-2018 IPR001623 DnaJ domain SMALA_RS11230 f1854f3c7f18d6c36c332e48127bfc1a 326 PRINTS PR00625 DnaJ domain signature 40 60 1.5E-20 T 29-03-2018 IPR001623 DnaJ domain SMALA_RS11230 f1854f3c7f18d6c36c332e48127bfc1a 326 PRINTS PR00625 DnaJ domain signature 60 79 1.5E-20 T 29-03-2018 IPR001623 DnaJ domain SMALA_RS11230 f1854f3c7f18d6c36c332e48127bfc1a 326 PRINTS PR00625 DnaJ domain signature 24 39 1.5E-20 T 29-03-2018 IPR001623 DnaJ domain SMALA_RS11230 f1854f3c7f18d6c36c332e48127bfc1a 326 Gene3D G3DSA:2.60.260.20 149 220 1.5E-15 T 29-03-2018 SMALA_RS11230 f1854f3c7f18d6c36c332e48127bfc1a 326 Pfam PF01556 DnaJ C terminal domain 154 300 7.2E-36 T 29-03-2018 IPR002939 Chaperone DnaJ, C-terminal SMALA_RS11230 f1854f3c7f18d6c36c332e48127bfc1a 326 SUPERFAMILY SSF46565 3 108 1.83E-29 T 29-03-2018 IPR001623 DnaJ domain SMALA_RS11230 f1854f3c7f18d6c36c332e48127bfc1a 326 Gene3D G3DSA:1.10.287.110 1 138 4.2E-32 T 29-03-2018 IPR001623 DnaJ domain SMALA_RS11230 f1854f3c7f18d6c36c332e48127bfc1a 326 Gene3D G3DSA:2.60.260.20 227 305 6.9E-22 T 29-03-2018 SMALA_RS29755 85ead27f0edf39010f52a9465a849003 1285 Gene3D G3DSA:3.30.2080.10 993 1159 2.1E-61 T 29-03-2018 SMALA_RS29755 85ead27f0edf39010f52a9465a849003 1285 Pfam PF07971 Glycosyl hydrolase family 92 620 1146 3.5E-147 T 29-03-2018 IPR012939 Glycosyl hydrolase family 92 SMALA_RS29755 85ead27f0edf39010f52a9465a849003 1285 SUPERFAMILY SSF48208 643 1129 1.26E-15 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 SMALA_RS29755 85ead27f0edf39010f52a9465a849003 1285 TIGRFAM TIGR01180 aman2_put: putative alpha-1,2-mannosidase 411 1149 3.8E-140 T 29-03-2018 IPR005887 Alpha-1,2-mannosidase, putative SMALA_RS29755 85ead27f0edf39010f52a9465a849003 1285 Pfam PF00754 F5/8 type C domain 100 221 9.2E-13 T 29-03-2018 IPR000421 Coagulation factor 5/8 C-terminal domain SMALA_RS29755 85ead27f0edf39010f52a9465a849003 1285 Gene3D G3DSA:1.20.1050.60 746 839 1.0E-28 T 29-03-2018 SMALA_RS29755 85ead27f0edf39010f52a9465a849003 1285 SUPERFAMILY SSF49785 105 214 6.8E-14 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS29755 85ead27f0edf39010f52a9465a849003 1285 Gene3D G3DSA:2.70.98.10 407 706 1.3E-78 T 29-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 SMALA_RS29755 85ead27f0edf39010f52a9465a849003 1285 Gene3D G3DSA:2.60.120.260 90 242 5.4E-22 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS29755 85ead27f0edf39010f52a9465a849003 1285 Gene3D G3DSA:2.60.120.260 1174 1285 2.9E-6 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS17780 0c9ec20a92c50b659a2042df0264e137 253 SMART SM00855 7 193 2.2E-23 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SMALA_RS17780 0c9ec20a92c50b659a2042df0264e137 253 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 8 210 5.6E-29 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SMALA_RS17780 0c9ec20a92c50b659a2042df0264e137 253 Hamap MF_01039 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [gpmA]. 5 234 42.275 T 29-03-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 SMALA_RS17780 0c9ec20a92c50b659a2042df0264e137 253 PIRSF PIRSF000709 148 218 1.5 T 29-03-2018 SMALA_RS17780 0c9ec20a92c50b659a2042df0264e137 253 PIRSF PIRSF000709 4 113 0.0072 T 29-03-2018 SMALA_RS17780 0c9ec20a92c50b659a2042df0264e137 253 SUPERFAMILY SSF53254 6 226 1.88E-69 T 29-03-2018 IPR029033 Histidine phosphatase superfamily SMALA_RS17780 0c9ec20a92c50b659a2042df0264e137 253 TIGRFAM TIGR01258 pgm_1: phosphoglycerate mutase 1 family 7 251 5.8E-112 T 29-03-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 SMALA_RS17780 0c9ec20a92c50b659a2042df0264e137 253 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 10 19 - T 29-03-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 SMALA_RS17780 0c9ec20a92c50b659a2042df0264e137 253 Gene3D G3DSA:3.40.50.1240 5 253 1.1E-56 T 29-03-2018 IPR029033 Histidine phosphatase superfamily SMALA_RS23480 038d6e09d194ddc1010b50616d20a562 255 PRINTS PR00502 NUDIX hydrolase family signature 136 150 6.9E-5 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMALA_RS23480 038d6e09d194ddc1010b50616d20a562 255 PRINTS PR00502 NUDIX hydrolase family signature 150 165 6.9E-5 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMALA_RS23480 038d6e09d194ddc1010b50616d20a562 255 ProSitePatterns PS00893 Nudix box signature. 141 162 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 SMALA_RS23480 038d6e09d194ddc1010b50616d20a562 255 Gene3D G3DSA:2.30.130.30 1 86 1.2E-12 T 29-03-2018 SMALA_RS23480 038d6e09d194ddc1010b50616d20a562 255 Pfam PF00293 NUDIX domain 108 224 1.3E-11 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SMALA_RS23480 038d6e09d194ddc1010b50616d20a562 255 Gene3D G3DSA:3.90.79.10 99 242 6.5E-18 T 29-03-2018 SMALA_RS23480 038d6e09d194ddc1010b50616d20a562 255 SUPERFAMILY SSF88697 5 86 7.21E-7 T 29-03-2018 IPR015947 PUA-like domain SMALA_RS23480 038d6e09d194ddc1010b50616d20a562 255 SUPERFAMILY SSF55811 94 234 1.76E-18 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMALA_RS05725 c59cc6abd81ba51fd393013ad1c69e43 145 SUPERFAMILY SSF55961 3 138 2.65E-19 T 29-03-2018 SMALA_RS05725 c59cc6abd81ba51fd393013ad1c69e43 145 Gene3D G3DSA:3.30.530.20 1 144 1.1E-21 T 29-03-2018 IPR023393 START-like domain SMALA_RS05725 c59cc6abd81ba51fd393013ad1c69e43 145 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 4 139 9.7E-18 T 29-03-2018 IPR019587 Polyketide cyclase/dehydrase SMALA_RS05970 4a470ad17156fa7eaecf422c9e26ec02 458 Pfam PF00581 Rhodanese-like domain 368 443 3.4E-7 T 29-03-2018 IPR001763 Rhodanese-like domain SMALA_RS05970 4a470ad17156fa7eaecf422c9e26ec02 458 SMART SM00450 357 450 6.1E-14 T 29-03-2018 IPR001763 Rhodanese-like domain SMALA_RS05970 4a470ad17156fa7eaecf422c9e26ec02 458 Gene3D G3DSA:3.40.250.10 247 347 6.7E-7 T 29-03-2018 IPR001763 Rhodanese-like domain SMALA_RS05970 4a470ad17156fa7eaecf422c9e26ec02 458 SMART SM00849 13 180 4.0E-16 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS05970 4a470ad17156fa7eaecf422c9e26ec02 458 Gene3D G3DSA:3.40.250.10 348 456 4.3E-19 T 29-03-2018 IPR001763 Rhodanese-like domain SMALA_RS05970 4a470ad17156fa7eaecf422c9e26ec02 458 SUPERFAMILY SSF52821 352 452 2.88E-22 T 29-03-2018 IPR001763 Rhodanese-like domain SMALA_RS05970 4a470ad17156fa7eaecf422c9e26ec02 458 SUPERFAMILY SSF52821 220 353 3.4E-13 T 29-03-2018 IPR001763 Rhodanese-like domain SMALA_RS05970 4a470ad17156fa7eaecf422c9e26ec02 458 Gene3D G3DSA:3.60.15.10 1 245 6.5E-29 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS05970 4a470ad17156fa7eaecf422c9e26ec02 458 SUPERFAMILY SSF56281 8 241 4.2E-37 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS38750 42bbe2477aca7df90aacde8a1cab97ac 335 Gene3D G3DSA:1.10.10.10 1 84 2.0E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS38750 42bbe2477aca7df90aacde8a1cab97ac 335 Gene3D G3DSA:3.40.190.10 85 214 1.6E-20 T 29-03-2018 SMALA_RS38750 42bbe2477aca7df90aacde8a1cab97ac 335 Gene3D G3DSA:3.40.190.10 215 291 1.5E-15 T 29-03-2018 SMALA_RS38750 42bbe2477aca7df90aacde8a1cab97ac 335 Pfam PF03466 LysR substrate binding domain 89 316 1.1E-39 T 29-03-2018 IPR005119 LysR, substrate-binding SMALA_RS38750 42bbe2477aca7df90aacde8a1cab97ac 335 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 63 7.3E-15 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS38750 42bbe2477aca7df90aacde8a1cab97ac 335 SUPERFAMILY SSF46785 6 113 7.46E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS38750 42bbe2477aca7df90aacde8a1cab97ac 335 SUPERFAMILY SSF53850 89 321 5.43E-35 T 29-03-2018 SMALA_RS36675 ee61328ba4b5d523674239bbd8894a7e 636 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 377 600 1.2E-31 T 29-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 SMALA_RS36675 ee61328ba4b5d523674239bbd8894a7e 636 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 80 598 7.9E-29 T 29-03-2018 IPR005674 CocE/Serine esterase GO:0016787 SMALA_RS36675 ee61328ba4b5d523674239bbd8894a7e 636 SMART SM00939 365 621 1.8E-40 T 29-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 SMALA_RS36675 ee61328ba4b5d523674239bbd8894a7e 636 Gene3D G3DSA:3.40.50.1820 58 397 8.9E-45 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS36675 ee61328ba4b5d523674239bbd8894a7e 636 SUPERFAMILY SSF49785 442 624 3.4E-30 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS36675 ee61328ba4b5d523674239bbd8894a7e 636 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 74 348 4.0E-55 T 29-03-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 SMALA_RS36675 ee61328ba4b5d523674239bbd8894a7e 636 Gene3D G3DSA:2.60.120.260 398 625 2.5E-41 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS36675 ee61328ba4b5d523674239bbd8894a7e 636 SUPERFAMILY SSF53474 47 400 2.57E-62 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS29315 47d5e618bbc1c64f328940532fc7932c 303 SUPERFAMILY SSF53335 24 286 6.44E-35 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS29315 47d5e618bbc1c64f328940532fc7932c 303 Gene3D G3DSA:3.40.50.150 62 264 4.9E-27 T 29-03-2018 SMALA_RS29315 47d5e618bbc1c64f328940532fc7932c 303 Pfam PF13649 Methyltransferase domain 98 192 6.2E-11 T 29-03-2018 SMALA_RS04205 4e9f6de79ce663e9d63eb18833479156 229 SMART SM00014 90 206 3.8E-14 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMALA_RS04205 4e9f6de79ce663e9d63eb18833479156 229 Pfam PF01569 PAP2 superfamily 93 207 7.6E-21 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMALA_RS04205 4e9f6de79ce663e9d63eb18833479156 229 SUPERFAMILY SSF48317 8 212 9.16E-32 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMALA_RS04205 4e9f6de79ce663e9d63eb18833479156 229 Gene3D G3DSA:1.20.144.10 36 226 4.1E-27 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMALA_RS16940 d496f203f59b6e7258b66aa207c53907 823 Gene3D G3DSA:3.40.50.300 70 354 5.6E-63 T 29-03-2018 SMALA_RS16940 d496f203f59b6e7258b66aa207c53907 823 Pfam PF00580 UvrD/REP helicase N-terminal domain 76 344 4.7E-78 T 29-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 SMALA_RS16940 d496f203f59b6e7258b66aa207c53907 823 Gene3D G3DSA:3.40.50.300 492 736 6.6E-51 T 29-03-2018 SMALA_RS16940 d496f203f59b6e7258b66aa207c53907 823 SUPERFAMILY SSF52540 71 719 8.04E-179 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS16940 d496f203f59b6e7258b66aa207c53907 823 TIGRFAM TIGR01073 pcrA: ATP-dependent DNA helicase PcrA 72 821 0.0 T 29-03-2018 IPR005751 ATP-dependent DNA helicase PcrA GO:0004003|GO:0005737|GO:0006268 SMALA_RS16940 d496f203f59b6e7258b66aa207c53907 823 Pfam PF13361 UvrD-like helicase C-terminal domain 350 692 3.0E-67 T 29-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 SMALA_RS16940 d496f203f59b6e7258b66aa207c53907 823 Gene3D G3DSA:3.40.50.300 355 458 2.6E-27 T 29-03-2018 SMALA_RS10835 169a47ae806c1d68d748041d0d65edda 215 Gene3D G3DSA:3.40.50.2300 1 131 8.6E-21 T 29-03-2018 SMALA_RS10835 169a47ae806c1d68d748041d0d65edda 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 193 2.6E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS10835 169a47ae806c1d68d748041d0d65edda 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 165 2.6E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS10835 169a47ae806c1d68d748041d0d65edda 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 181 2.6E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS10835 169a47ae806c1d68d748041d0d65edda 215 Pfam PF00072 Response regulator receiver domain 3 116 1.0E-12 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS10835 169a47ae806c1d68d748041d0d65edda 215 Pfam PF00196 Bacterial regulatory proteins, luxR family 150 195 2.7E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS10835 169a47ae806c1d68d748041d0d65edda 215 SUPERFAMILY SSF52172 2 162 1.7E-18 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS10835 169a47ae806c1d68d748041d0d65edda 215 SMART SM00421 148 210 4.0E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS10835 169a47ae806c1d68d748041d0d65edda 215 Gene3D G3DSA:1.10.10.10 132 215 1.0E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS10835 169a47ae806c1d68d748041d0d65edda 215 SMART SM00448 1 120 1.8E-8 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS10835 169a47ae806c1d68d748041d0d65edda 215 SUPERFAMILY SSF46894 146 196 4.0E-13 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS28345 351996876ff6113809b8c3a72e802fad 383 Pfam PF00005 ABC transporter 26 165 1.9E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS28345 351996876ff6113809b8c3a72e802fad 383 Pfam PF08402 TOBE domain 284 364 1.9E-15 T 29-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 SMALA_RS28345 351996876ff6113809b8c3a72e802fad 383 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS28345 351996876ff6113809b8c3a72e802fad 383 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 40 362 1.9E-111 T 29-03-2018 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 SMALA_RS28345 351996876ff6113809b8c3a72e802fad 383 SMART SM00382 34 262 4.6E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS28345 351996876ff6113809b8c3a72e802fad 383 Gene3D G3DSA:2.40.50.100 246 304 1.6E-9 T 29-03-2018 SMALA_RS28345 351996876ff6113809b8c3a72e802fad 383 Gene3D G3DSA:3.40.50.300 1 245 1.5E-70 T 29-03-2018 SMALA_RS28345 351996876ff6113809b8c3a72e802fad 383 SUPERFAMILY SSF50331 241 364 3.12E-17 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal SMALA_RS28345 351996876ff6113809b8c3a72e802fad 383 SUPERFAMILY SSF52540 10 247 2.13E-86 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS02270 011cc82b0052d130b2987b529bb6a355 377 Gene3D G3DSA:3.30.360.10 157 374 6.3E-22 T 29-03-2018 SMALA_RS02270 011cc82b0052d130b2987b529bb6a355 377 SUPERFAMILY SSF55347 149 340 9.97E-22 T 29-03-2018 SMALA_RS02270 011cc82b0052d130b2987b529bb6a355 377 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 149 201 1.4E-4 T 29-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 SMALA_RS02270 011cc82b0052d130b2987b529bb6a355 377 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 11 129 5.6E-20 T 29-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 SMALA_RS02270 011cc82b0052d130b2987b529bb6a355 377 Gene3D G3DSA:3.40.50.720 2 156 2.4E-29 T 29-03-2018 SMALA_RS02270 011cc82b0052d130b2987b529bb6a355 377 SUPERFAMILY SSF51735 8 162 6.36E-32 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS40140 1ea071545bfbee0dcb5bd27bed615ddb 303 Gene3D G3DSA:1.10.3720.10 47 297 3.1E-25 T 29-03-2018 SMALA_RS40140 1ea071545bfbee0dcb5bd27bed615ddb 303 SUPERFAMILY SSF161098 99 283 1.44E-31 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS40140 1ea071545bfbee0dcb5bd27bed615ddb 303 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 122 292 3.5E-27 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS37900 2fa9c69a5b42379a7a0a6c231eb3cf53 197 SUPERFAMILY SSF48498 86 194 4.17E-10 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS37900 2fa9c69a5b42379a7a0a6c231eb3cf53 197 Gene3D G3DSA:1.10.260.40 38 67 7.0E-12 T 29-03-2018 SMALA_RS37900 2fa9c69a5b42379a7a0a6c231eb3cf53 197 Pfam PF13305 WHG domain 92 172 2.0E-7 T 29-03-2018 IPR025996 WHG domain SMALA_RS37900 2fa9c69a5b42379a7a0a6c231eb3cf53 197 SUPERFAMILY SSF46689 4 78 3.54E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS37900 2fa9c69a5b42379a7a0a6c231eb3cf53 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 9.2E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS37900 2fa9c69a5b42379a7a0a6c231eb3cf53 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 9.2E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS37900 2fa9c69a5b42379a7a0a6c231eb3cf53 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 3.4E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS37900 2fa9c69a5b42379a7a0a6c231eb3cf53 197 Gene3D G3DSA:1.10.357.10 68 197 7.0E-22 T 29-03-2018 SMALA_RS37900 2fa9c69a5b42379a7a0a6c231eb3cf53 197 Gene3D G3DSA:1.10.10.60 1 37 1.3E-12 T 29-03-2018 SMALA_RS20580 0eeca69254678bee8e04b6ae42face36 147 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 25 85 1.1E-5 T 29-03-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 SMALA_RS20580 0eeca69254678bee8e04b6ae42face36 147 SUPERFAMILY SSF109854 4 90 7.32E-11 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes SMALA_RS20580 0eeca69254678bee8e04b6ae42face36 147 TIGRFAM TIGR03086 TIGR03086: TIGR03086 family protein 2 143 8.9E-30 T 29-03-2018 IPR017520 Conserved hypothetical protein CHP03086 SMALA_RS20580 0eeca69254678bee8e04b6ae42face36 147 Gene3D G3DSA:1.20.120.450 1 91 6.3E-11 T 29-03-2018 SMALA_RS14005 f5bdedfa8a0de2692a0195bbbf0e26ed 403 Pfam PF07282 Putative transposase DNA-binding domain 300 366 3.0E-23 T 29-03-2018 IPR010095 Transposase IS605, OrfB, C-terminal SMALA_RS14005 f5bdedfa8a0de2692a0195bbbf0e26ed 403 Pfam PF12323 Helix-turn-helix domain 9 50 1.9E-19 T 29-03-2018 IPR021027 Transposase, putative, helix-turn-helix domain SMALA_RS14005 f5bdedfa8a0de2692a0195bbbf0e26ed 403 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 255 327 2.1E-19 T 29-03-2018 IPR010095 Transposase IS605, OrfB, C-terminal SMALA_RS14005 f5bdedfa8a0de2692a0195bbbf0e26ed 403 Pfam PF01385 Probable transposase 181 286 1.0E-26 T 29-03-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 SMALA_RS31090 f564d07e2acba08c12661af3085a5333 412 SUPERFAMILY SSF53901 6 251 2.62E-55 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS31090 f564d07e2acba08c12661af3085a5333 412 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 9 244 4.1E-31 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS31090 f564d07e2acba08c12661af3085a5333 412 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 257 365 3.5E-20 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS31090 f564d07e2acba08c12661af3085a5333 412 Gene3D G3DSA:3.40.47.10 261 412 3.1E-24 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS31090 f564d07e2acba08c12661af3085a5333 412 SUPERFAMILY SSF53901 217 408 7.96E-45 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS31090 f564d07e2acba08c12661af3085a5333 412 SMART SM00825 Beta-ketoacyl synthase 8 410 1.6E-5 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS31090 f564d07e2acba08c12661af3085a5333 412 Gene3D G3DSA:3.40.47.10 8 260 2.9E-51 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS10170 43235c88011f15fefc612d9d675154ef 273 ProSitePatterns PS01102 Prokaryotic dksA C4-type zinc finger. 242 266 - T 29-03-2018 IPR020458 Zinc finger, DksA/TraR C4-type conserved site SMALA_RS10170 43235c88011f15fefc612d9d675154ef 273 SUPERFAMILY SSF109635 143 238 6.93E-9 T 29-03-2018 SMALA_RS10170 43235c88011f15fefc612d9d675154ef 273 SUPERFAMILY SSF57716 239 272 5.23E-9 T 29-03-2018 SMALA_RS10170 43235c88011f15fefc612d9d675154ef 273 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 237 272 2.1E-12 T 29-03-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 SMALA_RS10170 43235c88011f15fefc612d9d675154ef 273 PRINTS PR00618 DksA/TraR zinc finger signature 242 253 5.1E-5 T 29-03-2018 IPR020460 Zinc finger, DksA/TraR C4-type, bacteria SMALA_RS10170 43235c88011f15fefc612d9d675154ef 273 PRINTS PR00618 DksA/TraR zinc finger signature 254 266 5.1E-5 T 29-03-2018 IPR020460 Zinc finger, DksA/TraR C4-type, bacteria SMALA_RS18065 c835ecddcdc170f56c35a01dfe5563cb 227 SUPERFAMILY SSF161098 24 206 2.49E-35 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS18065 c835ecddcdc170f56c35a01dfe5563cb 227 Gene3D G3DSA:1.10.3720.10 17 221 1.9E-29 T 29-03-2018 SMALA_RS18065 c835ecddcdc170f56c35a01dfe5563cb 227 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 42 220 7.5E-19 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS11180 423b8edc27e22855e4a80efa599dd624 540 SUPERFAMILY SSF56300 234 511 8.25E-30 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SMALA_RS11180 423b8edc27e22855e4a80efa599dd624 540 SUPERFAMILY SSF56300 164 207 8.25E-30 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SMALA_RS11180 423b8edc27e22855e4a80efa599dd624 540 Pfam PF09423 PhoD-like phosphatase 168 509 4.4E-108 T 29-03-2018 IPR018946 Alkaline phosphatase D-related SMALA_RS11180 423b8edc27e22855e4a80efa599dd624 540 Gene3D G3DSA:3.60.21.10 162 525 3.2E-41 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SMALA_RS11180 423b8edc27e22855e4a80efa599dd624 540 Gene3D G3DSA:2.60.40.380 54 159 1.0E-6 T 29-03-2018 SMALA_RS11180 423b8edc27e22855e4a80efa599dd624 540 Pfam PF16655 PhoD-like phosphatase, N-terminal domain 58 155 3.0E-34 T 29-03-2018 IPR032093 Phospholipase D, N-terminal SMALA_RS35680 8deba07c7f220d935c16b1c00a836e25 801 Gene3D G3DSA:1.20.1610.10 466 640 1.1E-51 T 29-03-2018 SMALA_RS35680 8deba07c7f220d935c16b1c00a836e25 801 TIGRFAM TIGR01180 aman2_put: putative alpha-1,2-mannosidase 47 781 4.2E-170 T 29-03-2018 IPR005887 Alpha-1,2-mannosidase, putative SMALA_RS35680 8deba07c7f220d935c16b1c00a836e25 801 Gene3D G3DSA:2.70.98.10 46 346 2.0E-102 T 29-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 SMALA_RS35680 8deba07c7f220d935c16b1c00a836e25 801 Gene3D G3DSA:3.30.2080.10 641 790 3.1E-49 T 29-03-2018 SMALA_RS35680 8deba07c7f220d935c16b1c00a836e25 801 Pfam PF07971 Glycosyl hydrolase family 92 261 778 4.2E-150 T 29-03-2018 IPR012939 Glycosyl hydrolase family 92 SMALA_RS35680 8deba07c7f220d935c16b1c00a836e25 801 SUPERFAMILY SSF48208 287 764 1.81E-22 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 SMALA_RS35680 8deba07c7f220d935c16b1c00a836e25 801 Gene3D G3DSA:1.20.1050.60 369 465 2.5E-23 T 29-03-2018 SMALA_RS10220 ef824f7c4c6437821f7b41e75f90d6ad 453 Pfam PF01098 Cell cycle protein 64 413 2.1E-92 T 29-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 SMALA_RS10220 ef824f7c4c6437821f7b41e75f90d6ad 453 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 58 414 6.1E-112 T 29-03-2018 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 SMALA_RS10220 ef824f7c4c6437821f7b41e75f90d6ad 453 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 373 397 - T 29-03-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 SMALA_RS38520 850136c8e6292eb1956b28432864706f 311 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 5 18 - T 29-03-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 SMALA_RS38520 850136c8e6292eb1956b28432864706f 311 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 166 287 5.6E-29 T 29-03-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 SMALA_RS38520 850136c8e6292eb1956b28432864706f 311 SUPERFAMILY SSF48179 164 293 6.12E-25 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMALA_RS38520 850136c8e6292eb1956b28432864706f 311 PIRSF PIRSF000103 1 288 9.6E-62 T 29-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 SMALA_RS38520 850136c8e6292eb1956b28432864706f 311 Gene3D G3DSA:3.40.50.720 1 174 3.2E-29 T 29-03-2018 SMALA_RS38520 850136c8e6292eb1956b28432864706f 311 SUPERFAMILY SSF51735 1 156 2.06E-40 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS38520 850136c8e6292eb1956b28432864706f 311 Gene3D G3DSA:1.10.1040.10 175 293 3.1E-21 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMALA_RS38520 850136c8e6292eb1956b28432864706f 311 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 160 4.9E-42 T 29-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 SMALA_RS36365 ce550d3d8935d2dad65d15a024d06fe9 921 Pfam PF00703 Glycosyl hydrolases family 2 241 355 2.4E-13 T 29-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 SMALA_RS36365 ce550d3d8935d2dad65d15a024d06fe9 921 Gene3D G3DSA:2.60.40.10 692 814 7.6E-36 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS36365 ce550d3d8935d2dad65d15a024d06fe9 921 Gene3D G3DSA:2.60.40.10 236 353 2.5E-18 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS36365 ce550d3d8935d2dad65d15a024d06fe9 921 Gene3D G3DSA:2.60.120.260 68 235 6.5E-33 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS36365 ce550d3d8935d2dad65d15a024d06fe9 921 SUPERFAMILY SSF49303 797 914 5.83E-33 T 29-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 SMALA_RS36365 ce550d3d8935d2dad65d15a024d06fe9 921 Gene3D G3DSA:2.60.40.10 818 916 1.0E-30 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS36365 ce550d3d8935d2dad65d15a024d06fe9 921 SUPERFAMILY SSF51445 352 690 1.24E-67 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS36365 ce550d3d8935d2dad65d15a024d06fe9 921 SUPERFAMILY SSF49303 692 795 2.81E-23 T 29-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 SMALA_RS36365 ce550d3d8935d2dad65d15a024d06fe9 921 SUPERFAMILY SSF49303 240 355 6.83E-21 T 29-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 SMALA_RS36365 ce550d3d8935d2dad65d15a024d06fe9 921 SUPERFAMILY SSF49785 80 235 2.27E-34 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS36365 ce550d3d8935d2dad65d15a024d06fe9 921 Gene3D G3DSA:3.20.20.80 356 691 2.5E-53 T 29-03-2018 SMALA_RS39870 8bed0ccf9c654458d7833a8a6756127d 222 SUPERFAMILY SSF46894 147 216 8.84E-23 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS39870 8bed0ccf9c654458d7833a8a6756127d 222 Pfam PF00072 Response regulator receiver domain 4 118 7.9E-29 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS39870 8bed0ccf9c654458d7833a8a6756127d 222 SMART SM00421 152 209 1.5E-25 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS39870 8bed0ccf9c654458d7833a8a6756127d 222 Gene3D G3DSA:3.40.50.2300 1 135 2.0E-39 T 29-03-2018 SMALA_RS39870 8bed0ccf9c654458d7833a8a6756127d 222 SUPERFAMILY SSF52172 1 129 1.99E-35 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS39870 8bed0ccf9c654458d7833a8a6756127d 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 4.0E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS39870 8bed0ccf9c654458d7833a8a6756127d 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 4.0E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS39870 8bed0ccf9c654458d7833a8a6756127d 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 4.0E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS39870 8bed0ccf9c654458d7833a8a6756127d 222 SMART SM00448 2 117 2.2E-33 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS39870 8bed0ccf9c654458d7833a8a6756127d 222 Gene3D G3DSA:1.10.10.10 136 214 5.1E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS39870 8bed0ccf9c654458d7833a8a6756127d 222 Pfam PF00196 Bacterial regulatory proteins, luxR family 153 209 1.1E-19 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS37540 7aeeeba3836313eb76d8f7ef98c727ca 379 SUPERFAMILY SSF47203 236 370 9.83E-36 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMALA_RS37540 7aeeeba3836313eb76d8f7ef98c727ca 379 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 10 121 2.9E-13 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS37540 7aeeeba3836313eb76d8f7ef98c727ca 379 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 232 368 1.9E-27 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMALA_RS37540 7aeeeba3836313eb76d8f7ef98c727ca 379 Gene3D G3DSA:1.10.540.10 1 125 2.2E-20 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS37540 7aeeeba3836313eb76d8f7ef98c727ca 379 SUPERFAMILY SSF56645 4 214 3.14E-26 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMALA_RS37540 7aeeeba3836313eb76d8f7ef98c727ca 379 Gene3D G3DSA:1.20.140.10 205 373 4.2E-35 T 29-03-2018 SMALA_RS36970 0ac8408491a6fad98e52546eb082c5a4 140 SUPERFAMILY SSF54427 38 137 1.36E-33 T 29-03-2018 IPR032710 NTF2-like domain SMALA_RS36970 0ac8408491a6fad98e52546eb082c5a4 140 Hamap MF_00612 UPF0225 protein YchJ [ychJ]. 14 137 27.047 T 29-03-2018 IPR023006 Uncharacterised protein family UPF0225 SMALA_RS36970 0ac8408491a6fad98e52546eb082c5a4 140 Gene3D G3DSA:3.10.450.50 16 140 3.7E-44 T 29-03-2018 SMALA_RS41475 067b7a3ef6ff6ef6a7a156ded04c90d7 513 Gene3D G3DSA:3.40.462.10 228 274 6.5E-5 T 29-03-2018 IPR016170 Vanillyl-alcohol oxidase/Cytokinin dehydrogenase C-terminal domain SMALA_RS41475 067b7a3ef6ff6ef6a7a156ded04c90d7 513 Gene3D G3DSA:3.40.462.10 275 467 4.0E-32 T 29-03-2018 IPR016170 Vanillyl-alcohol oxidase/Cytokinin dehydrogenase C-terminal domain SMALA_RS41475 067b7a3ef6ff6ef6a7a156ded04c90d7 513 SUPERFAMILY SSF56176 9 217 7.94E-40 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SMALA_RS41475 067b7a3ef6ff6ef6a7a156ded04c90d7 513 Pfam PF01565 FAD binding domain 48 185 3.0E-23 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 SMALA_RS41475 067b7a3ef6ff6ef6a7a156ded04c90d7 513 Gene3D G3DSA:3.30.465.10 99 227 1.5E-22 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SMALA_RS41475 067b7a3ef6ff6ef6a7a156ded04c90d7 513 SUPERFAMILY SSF55103 380 508 2.83E-12 T 29-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 SMALA_RS41475 067b7a3ef6ff6ef6a7a156ded04c90d7 513 SUPERFAMILY SSF55103 271 338 2.83E-12 T 29-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 SMALA_RS41475 067b7a3ef6ff6ef6a7a156ded04c90d7 513 Gene3D G3DSA:3.30.43.10 1 98 3.1E-15 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 SMALA_RS26760 73a9ad54849be41405b6a6a022ab66cc 154 Gene3D G3DSA:3.40.50.300 2 62 5.3E-6 T 29-03-2018 SMALA_RS25475 5b6aa87e6930bca3cd0e126125fa4b34 292 Gene3D G3DSA:3.40.1190.20 22 162 1.5E-17 T 29-03-2018 IPR029056 Ribokinase-like SMALA_RS25475 5b6aa87e6930bca3cd0e126125fa4b34 292 SUPERFAMILY SSF53613 25 288 1.37E-28 T 29-03-2018 IPR029056 Ribokinase-like SMALA_RS25475 5b6aa87e6930bca3cd0e126125fa4b34 292 Gene3D G3DSA:3.40.1190.20 163 289 5.3E-12 T 29-03-2018 IPR029056 Ribokinase-like SMALA_RS25475 5b6aa87e6930bca3cd0e126125fa4b34 292 Pfam PF00294 pfkB family carbohydrate kinase 26 164 8.8E-10 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB SMALA_RS05250 5909e3acdb5292727c0ece14f0613c8a 346 Pfam PF00704 Glycosyl hydrolases family 18 116 240 3.4E-7 T 29-03-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 SMALA_RS05250 5909e3acdb5292727c0ece14f0613c8a 346 Gene3D G3DSA:3.20.20.80 50 326 3.2E-24 T 29-03-2018 SMALA_RS05250 5909e3acdb5292727c0ece14f0613c8a 346 SUPERFAMILY SSF51445 62 318 1.87E-17 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS23035 55131c5e843ba8285bcbc212aaad0b68 308 Pfam PF04199 Putative cyclase 86 239 6.5E-24 T 29-03-2018 IPR007325 Kynurenine formamidase GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 SMALA_RS23035 55131c5e843ba8285bcbc212aaad0b68 308 Gene3D G3DSA:3.50.30.50 45 308 1.2E-50 T 29-03-2018 SMALA_RS23035 55131c5e843ba8285bcbc212aaad0b68 308 SUPERFAMILY SSF102198 91 307 1.96E-24 T 29-03-2018 SMALA_RS10935 5799d3af7ad10bdcc037a142d7608b50 1082 SUPERFAMILY SSF81301 86 348 7.85E-70 T 29-03-2018 SMALA_RS10935 5799d3af7ad10bdcc037a142d7608b50 1082 SUPERFAMILY SSF81301 579 690 3.04E-13 T 29-03-2018 SMALA_RS10935 5799d3af7ad10bdcc037a142d7608b50 1082 Pfam PF08335 GlnD PII-uridylyltransferase 935 1077 1.0E-20 T 29-03-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 SMALA_RS10935 5799d3af7ad10bdcc037a142d7608b50 1082 Pfam PF08335 GlnD PII-uridylyltransferase 362 502 2.5E-37 T 29-03-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 SMALA_RS10935 5799d3af7ad10bdcc037a142d7608b50 1082 Gene3D G3DSA:1.20.120.330 351 506 1.1E-51 T 29-03-2018 SMALA_RS10935 5799d3af7ad10bdcc037a142d7608b50 1082 Gene3D G3DSA:1.20.120.330 923 1081 8.3E-48 T 29-03-2018 SMALA_RS10935 5799d3af7ad10bdcc037a142d7608b50 1082 SUPERFAMILY SSF81593 354 503 1.18E-39 T 29-03-2018 SMALA_RS10935 5799d3af7ad10bdcc037a142d7608b50 1082 Hamap MF_00802 Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme [glnE]. 101 1068 16.988 T 29-03-2018 IPR023057 Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme GO:0008882 SMALA_RS10935 5799d3af7ad10bdcc037a142d7608b50 1082 Gene3D G3DSA:3.30.460.10 761 920 2.7E-50 T 29-03-2018 SMALA_RS10935 5799d3af7ad10bdcc037a142d7608b50 1082 Gene3D G3DSA:3.30.460.10 188 348 5.1E-60 T 29-03-2018 SMALA_RS10935 5799d3af7ad10bdcc037a142d7608b50 1082 SUPERFAMILY SSF81593 927 1078 1.02E-35 T 29-03-2018 SMALA_RS10935 5799d3af7ad10bdcc037a142d7608b50 1082 SUPERFAMILY SSF81301 763 921 4.58E-43 T 29-03-2018 SMALA_RS10935 5799d3af7ad10bdcc037a142d7608b50 1082 Gene3D G3DSA:1.10.4050.10 582 686 4.7E-18 T 29-03-2018 SMALA_RS10935 5799d3af7ad10bdcc037a142d7608b50 1082 Gene3D G3DSA:1.10.4050.10 79 187 1.4E-20 T 29-03-2018 SMALA_RS10935 5799d3af7ad10bdcc037a142d7608b50 1082 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 105 339 3.0E-51 T 29-03-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 SMALA_RS10935 5799d3af7ad10bdcc037a142d7608b50 1082 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 763 911 1.4E-34 T 29-03-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 SMALA_RS10935 5799d3af7ad10bdcc037a142d7608b50 1082 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 607 690 5.0E-5 T 29-03-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 SMALA_RS33035 c1d33ab84ea5af85d3d99d908ce4ac7b 275 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 126 200 6.4E-5 T 29-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 SMALA_RS33035 c1d33ab84ea5af85d3d99d908ce4ac7b 275 SUPERFAMILY SSF53223 6 108 2.19E-27 T 29-03-2018 SMALA_RS33035 c1d33ab84ea5af85d3d99d908ce4ac7b 275 Gene3D G3DSA:3.40.50.10860 1 121 4.4E-42 T 29-03-2018 SMALA_RS33035 c1d33ab84ea5af85d3d99d908ce4ac7b 275 SUPERFAMILY SSF51735 109 263 3.72E-21 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS33035 c1d33ab84ea5af85d3d99d908ce4ac7b 275 Gene3D G3DSA:3.40.50.720 122 275 1.7E-24 T 29-03-2018 SMALA_RS33035 c1d33ab84ea5af85d3d99d908ce4ac7b 275 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 9 95 9.3E-25 T 29-03-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 SMALA_RS08185 9d5729b0a5fe0e7c4968f333bc93ea71 353 Pfam PF02401 LytB protein 19 295 1.3E-82 T 29-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 SMALA_RS08185 9d5729b0a5fe0e7c4968f333bc93ea71 353 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 17 299 35.12 T 29-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 SMALA_RS08185 9d5729b0a5fe0e7c4968f333bc93ea71 353 Gene3D G3DSA:3.40.50.2300 81 351 9.7E-4 T 29-03-2018 SMALA_RS08185 9d5729b0a5fe0e7c4968f333bc93ea71 353 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 19 297 1.0E-87 T 29-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 SMALA_RS24385 b45f2d98ff65f7d5885e8e9bfb893381 338 Gene3D G3DSA:3.40.50.300 1 267 3.2E-68 T 29-03-2018 SMALA_RS24385 b45f2d98ff65f7d5885e8e9bfb893381 338 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 12 309 2.2E-109 T 29-03-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 SMALA_RS24385 b45f2d98ff65f7d5885e8e9bfb893381 338 SUPERFAMILY SSF52540 5 226 9.32E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS24385 b45f2d98ff65f7d5885e8e9bfb893381 338 SMART SM00382 29 212 7.0E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS24385 b45f2d98ff65f7d5885e8e9bfb893381 338 Pfam PF13732 Domain of unknown function (DUF4162) 217 307 4.5E-9 T 29-03-2018 IPR025302 Domain of unknown function DUF4162 SMALA_RS24385 b45f2d98ff65f7d5885e8e9bfb893381 338 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS24385 b45f2d98ff65f7d5885e8e9bfb893381 338 Pfam PF00005 ABC transporter 20 163 1.5E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS20465 770f28181037d4a9949cf4fcf45b8621 707 Gene3D G3DSA:3.40.50.300 45 206 1.2E-13 T 29-03-2018 SMALA_RS20465 770f28181037d4a9949cf4fcf45b8621 707 Gene3D G3DSA:1.25.40.10 251 604 2.2E-13 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS20465 770f28181037d4a9949cf4fcf45b8621 707 Gene3D G3DSA:1.25.40.10 605 703 3.4E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS20465 770f28181037d4a9949cf4fcf45b8621 707 Pfam PF13424 Tetratricopeptide repeat 540 608 1.4E-7 T 29-03-2018 SMALA_RS20465 770f28181037d4a9949cf4fcf45b8621 707 SUPERFAMILY SSF48452 493 689 8.44E-22 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS20465 770f28181037d4a9949cf4fcf45b8621 707 PRINTS PR00364 Disease resistance protein signature 245 259 4.2E-5 T 29-03-2018 SMALA_RS20465 770f28181037d4a9949cf4fcf45b8621 707 PRINTS PR00364 Disease resistance protein signature 82 97 4.2E-5 T 29-03-2018 SMALA_RS20465 770f28181037d4a9949cf4fcf45b8621 707 Pfam PF00931 NB-ARC domain 80 303 4.3E-9 T 29-03-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207 SMALA_RS20465 770f28181037d4a9949cf4fcf45b8621 707 SUPERFAMILY SSF52540 42 306 4.89E-21 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS11945 b34204dbd8941252adbb688803760dfb 909 PIRSF PIRSF000156 10 903 0.0 T 29-03-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 SMALA_RS11945 b34204dbd8941252adbb688803760dfb 909 Gene3D G3DSA:3.40.50.970 69 484 5.1E-76 T 29-03-2018 SMALA_RS11945 b34204dbd8941252adbb688803760dfb 909 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 149 306 8.2E-8 T 29-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SMALA_RS11945 b34204dbd8941252adbb688803760dfb 909 Gene3D G3DSA:3.40.50.920 723 903 3.7E-40 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMALA_RS11945 b34204dbd8941252adbb688803760dfb 909 SUPERFAMILY SSF52922 719 894 1.79E-53 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMALA_RS11945 b34204dbd8941252adbb688803760dfb 909 SUPERFAMILY SSF52518 487 716 1.91E-86 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold SMALA_RS11945 b34204dbd8941252adbb688803760dfb 909 Gene3D G3DSA:3.40.50.970 486 721 7.8E-67 T 29-03-2018 SMALA_RS11945 b34204dbd8941252adbb688803760dfb 909 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 19 898 0.0 T 29-03-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 SMALA_RS11945 b34204dbd8941252adbb688803760dfb 909 SUPERFAMILY SSF52518 70 481 3.09E-122 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold SMALA_RS07600 7f3146bc5e7d465993a458fd82fb8433 187 SUPERFAMILY SSF88659 111 179 3.18E-14 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS07600 7f3146bc5e7d465993a458fd82fb8433 187 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 33 179 1.6E-16 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS07600 7f3146bc5e7d465993a458fd82fb8433 187 Pfam PF08281 Sigma-70, region 4 128 174 1.0E-12 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS07600 7f3146bc5e7d465993a458fd82fb8433 187 SUPERFAMILY SSF88946 26 91 2.43E-9 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS07600 7f3146bc5e7d465993a458fd82fb8433 187 Gene3D G3DSA:1.10.10.10 121 182 7.9E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS07600 7f3146bc5e7d465993a458fd82fb8433 187 Gene3D G3DSA:1.10.1740.10 23 101 1.3E-10 T 29-03-2018 SMALA_RS07600 7f3146bc5e7d465993a458fd82fb8433 187 Pfam PF04542 Sigma-70 region 2 35 95 4.8E-6 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS39000 475e29c71a10590411a1fe9edcdfda22 387 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 185 378 2.1E-39 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS39000 475e29c71a10590411a1fe9edcdfda22 387 SMART SM00331 157 380 3.5E-20 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS39000 475e29c71a10590411a1fe9edcdfda22 387 SUPERFAMILY SSF81606 173 378 7.06E-9 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS39000 475e29c71a10590411a1fe9edcdfda22 387 Gene3D G3DSA:3.60.40.10 122 379 9.6E-28 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS28320 f1ad37071b660204b24ac1b650b7e783 229 SUPERFAMILY SSF51695 11 224 1.28E-47 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 SMALA_RS28320 f1ad37071b660204b24ac1b650b7e783 229 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 13 220 2.7E-28 T 29-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 SMALA_RS28320 f1ad37071b660204b24ac1b650b7e783 229 Gene3D G3DSA:3.20.20.190 2 228 2.9E-48 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 SMALA_RS20655 317bf170084f3c6982f934b3fcf8f834 219 SUPERFAMILY SSF51064 137 192 5.1E-16 T 29-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 SMALA_RS20655 317bf170084f3c6982f934b3fcf8f834 219 Gene3D G3DSA:3.90.20.20 40 136 8.1E-18 T 29-03-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 SMALA_RS20655 317bf170084f3c6982f934b3fcf8f834 219 Pfam PF01025 GrpE 45 191 1.6E-35 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 SMALA_RS20655 317bf170084f3c6982f934b3fcf8f834 219 Gene3D G3DSA:2.30.22.10 137 197 6.5E-22 T 29-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 SMALA_RS20655 317bf170084f3c6982f934b3fcf8f834 219 SUPERFAMILY SSF58014 48 134 3.4E-18 T 29-03-2018 SMALA_RS20655 317bf170084f3c6982f934b3fcf8f834 219 ProSitePatterns PS01071 grpE protein signature. 146 189 - T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 SMALA_RS20655 317bf170084f3c6982f934b3fcf8f834 219 PRINTS PR00773 GrpE protein signature 170 189 4.2E-25 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 SMALA_RS20655 317bf170084f3c6982f934b3fcf8f834 219 PRINTS PR00773 GrpE protein signature 68 84 4.2E-25 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 SMALA_RS20655 317bf170084f3c6982f934b3fcf8f834 219 PRINTS PR00773 GrpE protein signature 143 158 4.2E-25 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 SMALA_RS20655 317bf170084f3c6982f934b3fcf8f834 219 PRINTS PR00773 GrpE protein signature 96 111 4.2E-25 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 SMALA_RS20655 317bf170084f3c6982f934b3fcf8f834 219 Hamap MF_01151 Protein GrpE [grpE]. 3 191 17.396 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 SMALA_RS31635 3dc2caaf14db420fcfb25da78d8843e2 224 SUPERFAMILY SSF54631 2 144 4.42E-34 T 29-03-2018 SMALA_RS31635 3dc2caaf14db420fcfb25da78d8843e2 224 Gene3D G3DSA:3.10.580.10 1 74 1.1E-14 T 29-03-2018 SMALA_RS31635 3dc2caaf14db420fcfb25da78d8843e2 224 Gene3D G3DSA:3.10.580.10 75 213 1.8E-18 T 29-03-2018 SMALA_RS31635 3dc2caaf14db420fcfb25da78d8843e2 224 Pfam PF04972 BON domain 145 212 6.3E-11 T 29-03-2018 IPR007055 BON domain SMALA_RS31635 3dc2caaf14db420fcfb25da78d8843e2 224 SMART SM00116 13 61 7.1E-6 T 29-03-2018 IPR000644 CBS domain SMALA_RS31635 3dc2caaf14db420fcfb25da78d8843e2 224 SMART SM00116 95 143 1.7E-14 T 29-03-2018 IPR000644 CBS domain SMALA_RS31635 3dc2caaf14db420fcfb25da78d8843e2 224 Pfam PF00571 CBS domain 6 60 4.0E-13 T 29-03-2018 IPR000644 CBS domain SMALA_RS31635 3dc2caaf14db420fcfb25da78d8843e2 224 Pfam PF00571 CBS domain 90 142 7.8E-17 T 29-03-2018 IPR000644 CBS domain SMALA_RS31635 3dc2caaf14db420fcfb25da78d8843e2 224 PIRSF PIRSF036990 4 223 1.5E-59 T 29-03-2018 IPR017080 Uncharacterised conserved protein UCP036990, CBS, BON SMALA_RS41270 78c3bc1080526dda046a0de6726bed7a 56 Pfam PF02641 Uncharacterized ACR, COG1993 10 52 4.9E-12 T 29-03-2018 IPR003793 Domain of unknown function DUF190 SMALA_RS41270 78c3bc1080526dda046a0de6726bed7a 56 SUPERFAMILY SSF54913 8 52 2.13E-10 T 29-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta SMALA_RS41270 78c3bc1080526dda046a0de6726bed7a 56 Gene3D G3DSA:3.30.70.120 4 56 3.1E-16 T 29-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal SMALA_RS10980 3dff2b119969ce88ba208763bce1b22d 286 Pfam PF02548 Ketopantoate hydroxymethyltransferase 23 280 6.6E-110 T 29-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 SMALA_RS10980 3dff2b119969ce88ba208763bce1b22d 286 Gene3D G3DSA:3.20.20.60 9 285 1.2E-85 T 29-03-2018 SMALA_RS10980 3dff2b119969ce88ba208763bce1b22d 286 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 31 286 4.4E-96 T 29-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 SMALA_RS10980 3dff2b119969ce88ba208763bce1b22d 286 PIRSF PIRSF000388 18 286 1.8E-109 T 29-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 SMALA_RS10980 3dff2b119969ce88ba208763bce1b22d 286 SUPERFAMILY SSF51621 23 285 2.16E-103 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SMALA_RS10980 3dff2b119969ce88ba208763bce1b22d 286 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 24 285 43.053 T 29-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 SMALA_RS13435 eca7ef3381ea45ef872706e81e22cf76 317 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 97 292 2.6E-8 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS13435 eca7ef3381ea45ef872706e81e22cf76 317 Gene3D G3DSA:1.20.58.370 2 52 7.0E-6 T 29-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain SMALA_RS13435 eca7ef3381ea45ef872706e81e22cf76 317 Gene3D G3DSA:1.10.3720.10 70 310 6.3E-40 T 29-03-2018 SMALA_RS13435 eca7ef3381ea45ef872706e81e22cf76 317 SUPERFAMILY SSF161098 62 302 9.42E-48 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS27825 9f32a61adaae1598906a67a748060b5d 192 SUPERFAMILY SSF52540 15 186 2.03E-22 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS27825 9f32a61adaae1598906a67a748060b5d 192 Gene3D G3DSA:3.40.50.300 4 190 5.4E-20 T 29-03-2018 SMALA_RS27825 9f32a61adaae1598906a67a748060b5d 192 Pfam PF03029 Conserved hypothetical ATP binding protein 20 187 2.2E-27 T 29-03-2018 IPR004130 GPN-loop GTPase SMALA_RS28510 93745f8d632965e4a02e783da3d779b8 415 TIGRFAM TIGR03923 T7SS_EccE: type VII secretion protein EccE 25 415 6.9E-65 T 29-03-2018 IPR021368 Type VII secretion system protein EccE SMALA_RS28510 93745f8d632965e4a02e783da3d779b8 415 Pfam PF11203 Putative type VII ESX secretion system translocon, EccE 208 316 2.5E-27 T 29-03-2018 IPR021368 Type VII secretion system protein EccE SMALA_RS17605 213fa5eaea8f4ee1a3f1c2ca23ac0c6f 361 SUPERFAMILY SSF50129 310 361 6.59E-9 T 29-03-2018 IPR011032 GroES-like SMALA_RS17605 213fa5eaea8f4ee1a3f1c2ca23ac0c6f 361 Gene3D G3DSA:3.40.50.10730 175 299 6.8E-36 T 29-03-2018 SMALA_RS17605 213fa5eaea8f4ee1a3f1c2ca23ac0c6f 361 Gene3D G3DSA:3.90.180.10 6 174 5.0E-46 T 29-03-2018 SMALA_RS17605 213fa5eaea8f4ee1a3f1c2ca23ac0c6f 361 SUPERFAMILY SSF50129 3 186 1.67E-54 T 29-03-2018 IPR011032 GroES-like SMALA_RS17605 213fa5eaea8f4ee1a3f1c2ca23ac0c6f 361 Pfam PF00107 Zinc-binding dehydrogenase 190 320 6.2E-30 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMALA_RS17605 213fa5eaea8f4ee1a3f1c2ca23ac0c6f 361 SMART SM00829 14 359 4.7E-5 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS17605 213fa5eaea8f4ee1a3f1c2ca23ac0c6f 361 SUPERFAMILY SSF51735 154 326 2.28E-45 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS17605 213fa5eaea8f4ee1a3f1c2ca23ac0c6f 361 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 148 6.2E-27 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS17605 213fa5eaea8f4ee1a3f1c2ca23ac0c6f 361 TIGRFAM TIGR03451 mycoS_dep_FDH: S-(hydroxymethyl)mycothiol dehydrogenase 5 361 4.9E-208 T 29-03-2018 IPR017816 S-(hydroxymethyl)mycothiol dehydrogenase KEGG: 00072+1.1.1.30|KEGG: 00650+1.1.1.30 SMALA_RS17605 213fa5eaea8f4ee1a3f1c2ca23ac0c6f 361 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 SMALA_RS05705 362eeccdd7de197a772d7777f928b2c5 532 Gene3D G3DSA:3.50.50.60 3 499 4.9E-18 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS05705 362eeccdd7de197a772d7777f928b2c5 532 SUPERFAMILY SSF51905 5 190 3.53E-20 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS05705 362eeccdd7de197a772d7777f928b2c5 532 SUPERFAMILY SSF51905 234 242 3.53E-20 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS05705 362eeccdd7de197a772d7777f928b2c5 532 SUPERFAMILY SSF51905 440 498 3.53E-20 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS05705 362eeccdd7de197a772d7777f928b2c5 532 Pfam PF12831 FAD dependent oxidoreductase 6 506 1.0E-107 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS33565 d5f333f9ee71103f9a89f1fea12caa31 153 SUPERFAMILY SSF55811 3 131 8.8E-27 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMALA_RS33565 d5f333f9ee71103f9a89f1fea12caa31 153 PRINTS PR00502 NUDIX hydrolase family signature 41 56 5.2E-5 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMALA_RS33565 d5f333f9ee71103f9a89f1fea12caa31 153 PRINTS PR00502 NUDIX hydrolase family signature 27 41 5.2E-5 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMALA_RS33565 d5f333f9ee71103f9a89f1fea12caa31 153 Gene3D G3DSA:3.90.79.10 1 140 1.3E-27 T 29-03-2018 SMALA_RS33565 d5f333f9ee71103f9a89f1fea12caa31 153 ProSitePatterns PS00893 Nudix box signature. 32 53 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 SMALA_RS33565 d5f333f9ee71103f9a89f1fea12caa31 153 Pfam PF00293 NUDIX domain 4 117 2.5E-14 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SMALA_RS02165 cf58c1021eabfb4f5c745f47b3dd09f4 298 SUPERFAMILY SSF56281 60 290 4.32E-39 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS02165 cf58c1021eabfb4f5c745f47b3dd09f4 298 Gene3D G3DSA:3.60.15.10 4 285 4.2E-47 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS02165 cf58c1021eabfb4f5c745f47b3dd09f4 298 SMART SM00849 58 273 5.3E-22 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS02165 cf58c1021eabfb4f5c745f47b3dd09f4 298 Pfam PF00753 Metallo-beta-lactamase superfamily 58 273 5.4E-25 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS29500 f624ef79c400b297473419daff2dacca 120 Gene3D G3DSA:3.40.1260.10 12 118 4.9E-15 T 29-03-2018 SMALA_RS29500 f624ef79c400b297473419daff2dacca 120 SUPERFAMILY SSF75169 14 111 9.55E-14 T 29-03-2018 IPR027396 DsrEFH-like SMALA_RS29500 f624ef79c400b297473419daff2dacca 120 Pfam PF02635 DsrE/DsrF-like family 34 111 5.9E-7 T 29-03-2018 IPR003787 Sulphur relay, DsrE/F-like protein SMALA_RS16730 9128ae943dc8565518e429301bf8db79 247 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 101 241 9.8E-7 T 29-03-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 SMALA_RS16730 9128ae943dc8565518e429301bf8db79 247 Gene3D G3DSA:1.10.10.60 1 41 1.1E-10 T 29-03-2018 SMALA_RS16730 9128ae943dc8565518e429301bf8db79 247 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 65 3.3E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS16730 9128ae943dc8565518e429301bf8db79 247 Gene3D G3DSA:1.10.357.10 92 247 2.8E-30 T 29-03-2018 SMALA_RS16730 9128ae943dc8565518e429301bf8db79 247 Gene3D G3DSA:1.10.260.40 42 78 3.7E-4 T 29-03-2018 SMALA_RS16730 9128ae943dc8565518e429301bf8db79 247 SUPERFAMILY SSF48498 100 245 1.22E-17 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS16730 9128ae943dc8565518e429301bf8db79 247 SUPERFAMILY SSF46689 10 75 2.31E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS26300 74910d77ba82efee3f4a2a073399e31e 423 SUPERFAMILY SSF53850 19 420 3.01E-68 T 29-03-2018 SMALA_RS26300 74910d77ba82efee3f4a2a073399e31e 423 Gene3D G3DSA:3.40.190.10 23 196 2.7E-33 T 29-03-2018 SMALA_RS26300 74910d77ba82efee3f4a2a073399e31e 423 Pfam PF13416 Bacterial extracellular solute-binding protein 58 361 1.2E-37 T 29-03-2018 SMALA_RS26300 74910d77ba82efee3f4a2a073399e31e 423 Gene3D G3DSA:3.40.190.10 203 378 7.1E-9 T 29-03-2018 SMALA_RS24165 0a9736b1df810d1f67254b4cd8e27e61 252 SMART SM00895 110 232 4.2E-23 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS24165 0a9736b1df810d1f67254b4cd8e27e61 252 Pfam PF07729 FCD domain 110 231 3.4E-28 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS24165 0a9736b1df810d1f67254b4cd8e27e61 252 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 59 75 2.1E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS24165 0a9736b1df810d1f67254b4cd8e27e61 252 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 45 59 2.1E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS24165 0a9736b1df810d1f67254b4cd8e27e61 252 Gene3D G3DSA:1.10.10.10 17 87 5.9E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS24165 0a9736b1df810d1f67254b4cd8e27e61 252 SUPERFAMILY SSF48008 109 239 5.23E-30 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS24165 0a9736b1df810d1f67254b4cd8e27e61 252 SUPERFAMILY SSF46785 21 89 1.57E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS24165 0a9736b1df810d1f67254b4cd8e27e61 252 Pfam PF00392 Bacterial regulatory proteins, gntR family 24 85 4.2E-18 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS24165 0a9736b1df810d1f67254b4cd8e27e61 252 SMART SM00345 26 85 8.2E-19 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS24165 0a9736b1df810d1f67254b4cd8e27e61 252 Gene3D G3DSA:1.20.120.530 90 251 9.8E-34 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS40745 fc9a2d0878ca9ddad6f8db4b602d7299 278 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS40745 fc9a2d0878ca9ddad6f8db4b602d7299 278 Gene3D G3DSA:3.40.50.300 8 231 2.8E-61 T 29-03-2018 SMALA_RS40745 fc9a2d0878ca9ddad6f8db4b602d7299 278 SUPERFAMILY SSF52540 13 246 5.82E-68 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS40745 fc9a2d0878ca9ddad6f8db4b602d7299 278 SMART SM00382 41 221 4.5E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS40745 fc9a2d0878ca9ddad6f8db4b602d7299 278 Pfam PF00005 ABC transporter 32 171 7.1E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS29855 d81c407892b3543ba3658cf99c58f5f2 463 SUPERFAMILY SSF51905 159 328 3.58E-27 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS29855 d81c407892b3543ba3658cf99c58f5f2 463 Gene3D G3DSA:3.50.50.60 1 147 1.4E-21 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS29855 d81c407892b3543ba3658cf99c58f5f2 463 SUPERFAMILY SSF51905 5 204 9.72E-46 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS29855 d81c407892b3543ba3658cf99c58f5f2 463 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 112 130 5.9E-20 T 29-03-2018 SMALA_RS29855 d81c407892b3543ba3658cf99c58f5f2 463 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 272 294 5.9E-20 T 29-03-2018 SMALA_RS29855 d81c407892b3543ba3658cf99c58f5f2 463 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 244 260 5.9E-20 T 29-03-2018 SMALA_RS29855 d81c407892b3543ba3658cf99c58f5f2 463 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 5.9E-20 T 29-03-2018 SMALA_RS29855 d81c407892b3543ba3658cf99c58f5f2 463 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 159 177 5.9E-20 T 29-03-2018 SMALA_RS29855 d81c407892b3543ba3658cf99c58f5f2 463 Gene3D G3DSA:3.40.50.720 148 323 1.6E-32 T 29-03-2018 SMALA_RS29855 d81c407892b3543ba3658cf99c58f5f2 463 SUPERFAMILY SSF55424 333 453 2.75E-31 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SMALA_RS29855 d81c407892b3543ba3658cf99c58f5f2 463 Gene3D G3DSA:3.30.390.30 336 463 2.1E-28 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SMALA_RS29855 d81c407892b3543ba3658cf99c58f5f2 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 2.4E-15 T 29-03-2018 SMALA_RS29855 d81c407892b3543ba3658cf99c58f5f2 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 287 294 2.4E-15 T 29-03-2018 SMALA_RS29855 d81c407892b3543ba3658cf99c58f5f2 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 159 184 2.4E-15 T 29-03-2018 SMALA_RS29855 d81c407892b3543ba3658cf99c58f5f2 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 245 259 2.4E-15 T 29-03-2018 SMALA_RS29855 d81c407892b3543ba3658cf99c58f5f2 463 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 317 1.2E-58 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS29855 d81c407892b3543ba3658cf99c58f5f2 463 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 340 441 5.7E-20 T 29-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 SMALA_RS28885 7ee4056b0cc91272fdd2f966fdfda8c4 510 Gene3D G3DSA:2.40.50.140 396 459 9.7E-4 T 29-03-2018 SMALA_RS28885 7ee4056b0cc91272fdd2f966fdfda8c4 510 Gene3D G3DSA:3.80.30.20 160 395 5.6E-54 T 29-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe SMALA_RS28885 7ee4056b0cc91272fdd2f966fdfda8c4 510 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 19 456 1.3E-145 T 29-03-2018 SMALA_RS28885 7ee4056b0cc91272fdd2f966fdfda8c4 510 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 167 187 - T 29-03-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 SMALA_RS28885 7ee4056b0cc91272fdd2f966fdfda8c4 510 Pfam PF00919 Uncharacterized protein family UPF0004 20 120 2.5E-26 T 29-03-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 SMALA_RS28885 7ee4056b0cc91272fdd2f966fdfda8c4 510 SUPERFAMILY SSF102114 149 389 3.14E-58 T 29-03-2018 SMALA_RS28885 7ee4056b0cc91272fdd2f966fdfda8c4 510 SMART SM00729 163 382 4.4E-59 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 SMALA_RS28885 7ee4056b0cc91272fdd2f966fdfda8c4 510 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 19 455 3.0E-154 T 29-03-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 SMALA_RS28885 7ee4056b0cc91272fdd2f966fdfda8c4 510 Pfam PF04055 Radical SAM superfamily 167 337 1.9E-29 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 SMALA_RS28885 7ee4056b0cc91272fdd2f966fdfda8c4 510 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 17 460 68.102 T 29-03-2018 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 SMALA_RS40490 72e5dd6ca935b5e12e59fa0923b83f62 432 SMART SM00388 215 279 2.9E-7 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS40490 72e5dd6ca935b5e12e59fa0923b83f62 432 SUPERFAMILY SSF158472 162 212 7.98E-6 T 29-03-2018 SMALA_RS40490 72e5dd6ca935b5e12e59fa0923b83f62 432 SUPERFAMILY SSF55874 292 424 8.9E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS40490 72e5dd6ca935b5e12e59fa0923b83f62 432 Gene3D G3DSA:1.10.287.130 205 275 3.9E-10 T 29-03-2018 SMALA_RS40490 72e5dd6ca935b5e12e59fa0923b83f62 432 SMART SM00387 324 424 6.9E-14 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS40490 72e5dd6ca935b5e12e59fa0923b83f62 432 Pfam PF00512 His Kinase A (phospho-acceptor) domain 217 275 1.4E-7 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS40490 72e5dd6ca935b5e12e59fa0923b83f62 432 Pfam PF00672 HAMP domain 162 210 2.6E-6 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMALA_RS40490 72e5dd6ca935b5e12e59fa0923b83f62 432 SMART SM00304 162 214 6.2E-8 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMALA_RS40490 72e5dd6ca935b5e12e59fa0923b83f62 432 SUPERFAMILY SSF47384 199 276 7.06E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS40490 72e5dd6ca935b5e12e59fa0923b83f62 432 Gene3D G3DSA:3.30.565.10 284 431 1.6E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS40490 72e5dd6ca935b5e12e59fa0923b83f62 432 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 329 423 2.1E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS27745 30d9538cee532dced7142cc6756c0876 194 Gene3D G3DSA:3.40.30.10 1 186 3.6E-12 T 29-03-2018 SMALA_RS27745 30d9538cee532dced7142cc6756c0876 194 Pfam PF00578 AhpC/TSA family 26 103 7.1E-8 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 SMALA_RS27745 30d9538cee532dced7142cc6756c0876 194 SUPERFAMILY SSF52833 25 99 8.48E-13 T 29-03-2018 IPR012336 Thioredoxin-like fold SMALA_RS27745 30d9538cee532dced7142cc6756c0876 194 SUPERFAMILY SSF52833 135 184 8.48E-13 T 29-03-2018 IPR012336 Thioredoxin-like fold SMALA_RS41265 127a7b0cb8d5c7ac808ce7cc67bbea1e 124 TIGRFAM TIGR00494 crcB: protein CrcB 4 118 1.0E-24 T 29-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 SMALA_RS41265 127a7b0cb8d5c7ac808ce7cc67bbea1e 124 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 4 115 4.2E-23 T 29-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 SMALA_RS41265 127a7b0cb8d5c7ac808ce7cc67bbea1e 124 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 3 120 18.44 T 29-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 SMALA_RS28235 a11e2e4ce11281c2279d053e19f5d254 260 PIRSF PIRSF005650 18 260 8.8E-89 T 29-03-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 SMALA_RS28235 a11e2e4ce11281c2279d053e19f5d254 260 Hamap MF_01220_B Uridylate kinase [pyrH]. 20 254 42.953 T 29-03-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 SMALA_RS28235 a11e2e4ce11281c2279d053e19f5d254 260 Gene3D G3DSA:3.40.1160.10 2 255 3.1E-39 T 29-03-2018 SMALA_RS28235 a11e2e4ce11281c2279d053e19f5d254 260 Pfam PF00696 Amino acid kinase family 24 232 8.5E-24 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase SMALA_RS28235 a11e2e4ce11281c2279d053e19f5d254 260 SUPERFAMILY SSF53633 22 255 1.24E-67 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase SMALA_RS28235 a11e2e4ce11281c2279d053e19f5d254 260 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 24 254 1.9E-90 T 29-03-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 SMALA_RS35535 a2d2da27b8c5443a5d55de5fb2c8e152 606 TIGRFAM TIGR04267 mod_HExxH: HEXXH motif domain 18 414 6.4E-126 T 29-03-2018 IPR026337 HEXXH motif domain SMALA_RS09280 a0eaea23403ec0d7db8e4195bdbb88d0 421 Pfam PF07730 Histidine kinase 220 284 1.4E-18 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMALA_RS09280 a0eaea23403ec0d7db8e4195bdbb88d0 421 Gene3D G3DSA:3.30.565.10 295 421 6.8E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS09280 a0eaea23403ec0d7db8e4195bdbb88d0 421 SUPERFAMILY SSF55874 304 417 1.57E-7 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS35770 2e5697e053b626006eeff11943578c23 272 Pfam PF04672 S-adenosyl methyltransferase 8 271 1.1E-108 T 29-03-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type SMALA_RS35770 2e5697e053b626006eeff11943578c23 272 SUPERFAMILY SSF53335 15 254 5.49E-42 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS35770 2e5697e053b626006eeff11943578c23 272 Gene3D G3DSA:3.40.50.150 3 272 9.4E-53 T 29-03-2018 SMALA_RS35770 2e5697e053b626006eeff11943578c23 272 PIRSF PIRSF017393 2 272 6.5E-100 T 29-03-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type SMALA_RS20730 528aeb5b294794d0bf4624049df845e9 524 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 206 513 19.894 T 29-03-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 SMALA_RS20730 528aeb5b294794d0bf4624049df845e9 524 SUPERFAMILY SSF53335 240 477 2.58E-47 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS20730 528aeb5b294794d0bf4624049df845e9 524 Gene3D G3DSA:3.40.50.150 291 508 4.9E-42 T 29-03-2018 SMALA_RS20730 528aeb5b294794d0bf4624049df845e9 524 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 313 326 - T 29-03-2018 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 SMALA_RS20730 528aeb5b294794d0bf4624049df845e9 524 SUPERFAMILY SSF103473 9 212 6.54E-10 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS20730 528aeb5b294794d0bf4624049df845e9 524 Pfam PF01564 Spermine/spermidine synthase domain 294 454 3.6E-22 T 29-03-2018 SMALA_RS00980 fbec154ad0f1eecabd8a0e186e43f39f 404 Gene3D G3DSA:3.30.70.1350 292 383 1.3E-5 T 29-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain SMALA_RS00980 fbec154ad0f1eecabd8a0e186e43f39f 404 Pfam PF01545 Cation efflux family 81 291 3.8E-34 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 SMALA_RS00980 fbec154ad0f1eecabd8a0e186e43f39f 404 SUPERFAMILY SSF161111 77 293 3.79E-34 T 29-03-2018 SMALA_RS00980 fbec154ad0f1eecabd8a0e186e43f39f 404 Gene3D G3DSA:1.20.1510.10 76 291 1.1E-28 T 29-03-2018 SMALA_RS00980 fbec154ad0f1eecabd8a0e186e43f39f 404 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 79 374 4.6E-54 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 SMALA_RS25465 c0373e18faaf2541d0d2cef0bb714f48 435 Gene3D G3DSA:3.90.1150.10 13 169 2.6E-31 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS25465 c0373e18faaf2541d0d2cef0bb714f48 435 Gene3D G3DSA:3.40.640.10 185 316 4.5E-37 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS25465 c0373e18faaf2541d0d2cef0bb714f48 435 SUPERFAMILY SSF53383 24 431 8.8E-110 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS25465 c0373e18faaf2541d0d2cef0bb714f48 435 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 247 284 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMALA_RS25465 c0373e18faaf2541d0d2cef0bb714f48 435 Pfam PF00202 Aminotransferase class-III 32 429 9.8E-93 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMALA_RS25465 c0373e18faaf2541d0d2cef0bb714f48 435 Gene3D G3DSA:3.90.1150.10 317 435 5.5E-30 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS25465 c0373e18faaf2541d0d2cef0bb714f48 435 PIRSF PIRSF000521 132 433 1.6E-32 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMALA_RS25465 c0373e18faaf2541d0d2cef0bb714f48 435 PIRSF PIRSF000521 32 134 1.8E-8 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMALA_RS10255 cedbc6682a02a67d900bfc07a95228fa 320 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 3 313 2.8E-93 T 29-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SMALA_RS10255 cedbc6682a02a67d900bfc07a95228fa 320 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 7 314 36.681 T 29-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SMALA_RS10255 cedbc6682a02a67d900bfc07a95228fa 320 Pfam PF01795 MraW methylase family 5 313 1.3E-112 T 29-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SMALA_RS10255 cedbc6682a02a67d900bfc07a95228fa 320 PIRSF PIRSF004486 1 315 1.3E-97 T 29-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SMALA_RS10255 cedbc6682a02a67d900bfc07a95228fa 320 Gene3D G3DSA:1.10.150.170 121 221 5.0E-36 T 29-03-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SMALA_RS10255 cedbc6682a02a67d900bfc07a95228fa 320 SUPERFAMILY SSF81799 118 219 3.01E-32 T 29-03-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SMALA_RS10255 cedbc6682a02a67d900bfc07a95228fa 320 SUPERFAMILY SSF53335 7 117 4.6E-42 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS10255 cedbc6682a02a67d900bfc07a95228fa 320 SUPERFAMILY SSF53335 219 314 4.6E-42 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS10255 cedbc6682a02a67d900bfc07a95228fa 320 Gene3D G3DSA:3.40.50.720 4 120 3.2E-5 T 29-03-2018 SMALA_RS16610 f0c781e436542478d59b11285ea47491 243 Gene3D G3DSA:1.10.10.10 6 82 1.8E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS16610 f0c781e436542478d59b11285ea47491 243 SMART SM00895 109 233 4.1E-18 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS16610 f0c781e436542478d59b11285ea47491 243 SUPERFAMILY SSF46785 14 84 4.96E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS16610 f0c781e436542478d59b11285ea47491 243 SMART SM00345 22 80 5.3E-10 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS16610 f0c781e436542478d59b11285ea47491 243 Pfam PF00392 Bacterial regulatory proteins, gntR family 22 80 7.7E-12 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS16610 f0c781e436542478d59b11285ea47491 243 Gene3D G3DSA:1.20.120.530 103 239 8.3E-22 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS16610 f0c781e436542478d59b11285ea47491 243 Pfam PF07729 FCD domain 110 229 3.1E-21 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS16610 f0c781e436542478d59b11285ea47491 243 SUPERFAMILY SSF48008 106 235 9.94E-22 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS18350 3e9624b03ea1b470591b4896d861ee4d 307 SUPERFAMILY SSF88659 156 224 3.79E-14 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS18350 3e9624b03ea1b470591b4896d861ee4d 307 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 107 120 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS18350 3e9624b03ea1b470591b4896d861ee4d 307 Pfam PF04539 Sigma-70 region 3 163 221 8.3E-11 T 29-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS18350 3e9624b03ea1b470591b4896d861ee4d 307 Gene3D G3DSA:1.10.601.10 11 151 6.7E-28 T 29-03-2018 SMALA_RS18350 3e9624b03ea1b470591b4896d861ee4d 307 Pfam PF04542 Sigma-70 region 2 83 152 6.9E-18 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS18350 3e9624b03ea1b470591b4896d861ee4d 307 Gene3D G3DSA:1.10.10.10 227 307 3.3E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS18350 3e9624b03ea1b470591b4896d861ee4d 307 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 77 302 1.1E-87 T 29-03-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS18350 3e9624b03ea1b470591b4896d861ee4d 307 Pfam PF04545 Sigma-70, region 4 254 301 1.7E-17 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS18350 3e9624b03ea1b470591b4896d861ee4d 307 Gene3D G3DSA:1.10.10.10 152 205 3.9E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS18350 3e9624b03ea1b470591b4896d861ee4d 307 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 80 301 3.9E-35 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS18350 3e9624b03ea1b470591b4896d861ee4d 307 SUPERFAMILY SSF88659 228 303 4.49E-17 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS18350 3e9624b03ea1b470591b4896d861ee4d 307 SUPERFAMILY SSF88946 52 152 8.9E-33 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS18350 3e9624b03ea1b470591b4896d861ee4d 307 PRINTS PR00046 Major sigma-70 factor signature 288 299 6.6E-12 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS18350 3e9624b03ea1b470591b4896d861ee4d 307 PRINTS PR00046 Major sigma-70 factor signature 256 268 6.6E-12 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS18350 3e9624b03ea1b470591b4896d861ee4d 307 PRINTS PR00046 Major sigma-70 factor signature 107 120 6.6E-12 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS18350 3e9624b03ea1b470591b4896d861ee4d 307 PRINTS PR00046 Major sigma-70 factor signature 273 288 6.6E-12 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS33990 026d352af129ba4ba9a69a96ba3e5c1b 275 SUPERFAMILY SSF52540 14 238 2.41E-65 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS33990 026d352af129ba4ba9a69a96ba3e5c1b 275 Pfam PF00005 ABC transporter 34 168 1.1E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS33990 026d352af129ba4ba9a69a96ba3e5c1b 275 Gene3D G3DSA:3.40.50.300 9 231 1.7E-59 T 29-03-2018 SMALA_RS33990 026d352af129ba4ba9a69a96ba3e5c1b 275 SMART SM00382 41 227 2.2E-19 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS33990 026d352af129ba4ba9a69a96ba3e5c1b 275 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS10330 c24f3ebefe3e6731d122793548d196a2 121 Pfam PF12728 Helix-turn-helix domain 15 48 1.3E-6 T 29-03-2018 SMALA_RS10330 c24f3ebefe3e6731d122793548d196a2 121 Gene3D G3DSA:1.10.1660.10 3 120 2.2E-5 T 29-03-2018 SMALA_RS11430 d3d92fb2552f180f6a481edfa79c8fb8 204 Gene3D G3DSA:1.10.357.10 19 196 1.0E-31 T 29-03-2018 SMALA_RS11430 d3d92fb2552f180f6a481edfa79c8fb8 204 SUPERFAMILY SSF46689 14 84 1.45E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS11430 d3d92fb2552f180f6a481edfa79c8fb8 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 1.9E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS11430 d3d92fb2552f180f6a481edfa79c8fb8 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 1.9E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS11430 d3d92fb2552f180f6a481edfa79c8fb8 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 68 6.5E-15 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS07395 d01e09bce27fa20ed80441eb1c0f86c9 258 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 248 6.7E-53 T 29-03-2018 SMALA_RS07395 d01e09bce27fa20ed80441eb1c0f86c9 258 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMALA_RS07395 d01e09bce27fa20ed80441eb1c0f86c9 258 Gene3D G3DSA:3.40.50.720 1 45 1.4E-8 T 29-03-2018 SMALA_RS07395 d01e09bce27fa20ed80441eb1c0f86c9 258 Gene3D G3DSA:3.40.50.720 46 254 1.3E-54 T 29-03-2018 SMALA_RS07395 d01e09bce27fa20ed80441eb1c0f86c9 258 SUPERFAMILY SSF51735 9 248 9.39E-67 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS07395 d01e09bce27fa20ed80441eb1c0f86c9 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 1.5E-32 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS07395 d01e09bce27fa20ed80441eb1c0f86c9 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 1.5E-32 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS07395 d01e09bce27fa20ed80441eb1c0f86c9 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 1.5E-32 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS07395 d01e09bce27fa20ed80441eb1c0f86c9 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 1.5E-32 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS07395 d01e09bce27fa20ed80441eb1c0f86c9 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 1.5E-32 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS13390 2990bd37fe97e6d5194a5b7257d1caa3 556 Gene3D G3DSA:2.60.120.260 470 544 1.1E-4 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS13390 2990bd37fe97e6d5194a5b7257d1caa3 556 SUPERFAMILY SSF51445 382 459 7.47E-80 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS13390 2990bd37fe97e6d5194a5b7257d1caa3 556 SUPERFAMILY SSF51445 264 348 7.47E-80 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS13390 2990bd37fe97e6d5194a5b7257d1caa3 556 SUPERFAMILY SSF51445 52 207 7.47E-80 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS13390 2990bd37fe97e6d5194a5b7257d1caa3 556 Gene3D G3DSA:3.20.20.80 42 463 2.7E-97 T 29-03-2018 SMALA_RS13390 2990bd37fe97e6d5194a5b7257d1caa3 556 SMART SM00812 54 499 3.5E-13 T 29-03-2018 IPR000933 Glycoside hydrolase, family 29 GO:0004560|GO:0005975 KEGG: 00511+3.2.1.51|Reactome: R-HSA-6798695 SMALA_RS13390 2990bd37fe97e6d5194a5b7257d1caa3 556 Pfam PF01120 Alpha-L-fucosidase 96 456 1.4E-31 T 29-03-2018 IPR000933 Glycoside hydrolase, family 29 GO:0004560|GO:0005975 KEGG: 00511+3.2.1.51|Reactome: R-HSA-6798695 SMALA_RS19090 fd47955c3ede298639eacdda7b231b8a 260 Gene3D G3DSA:1.10.10.60 6 73 2.9E-17 T 29-03-2018 SMALA_RS19090 fd47955c3ede298639eacdda7b231b8a 260 Gene3D G3DSA:1.10.357.10 119 260 3.9E-34 T 29-03-2018 SMALA_RS19090 fd47955c3ede298639eacdda7b231b8a 260 Pfam PF00440 Bacterial regulatory proteins, tetR family 38 82 1.8E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS19090 fd47955c3ede298639eacdda7b231b8a 260 Gene3D G3DSA:1.10.10.60 74 118 2.6E-5 T 29-03-2018 SMALA_RS19090 fd47955c3ede298639eacdda7b231b8a 260 SUPERFAMILY SSF46689 37 92 6.31E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS19090 fd47955c3ede298639eacdda7b231b8a 260 SUPERFAMILY SSF48498 114 258 5.34E-28 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS19090 fd47955c3ede298639eacdda7b231b8a 260 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 109 256 5.9E-19 T 29-03-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 SMALA_RS14060 f44790f5bbccc6fcf37e84592f4ffe3f 308 Pfam PF12802 MarR family 31 86 3.7E-10 T 29-03-2018 SMALA_RS14060 f44790f5bbccc6fcf37e84592f4ffe3f 308 Pfam PF00583 Acetyltransferase (GNAT) family 191 278 4.0E-15 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SMALA_RS14060 f44790f5bbccc6fcf37e84592f4ffe3f 308 SMART SM00347 23 123 4.6E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS14060 f44790f5bbccc6fcf37e84592f4ffe3f 308 SUPERFAMILY SSF55729 145 289 1.86E-26 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS14060 f44790f5bbccc6fcf37e84592f4ffe3f 308 Gene3D G3DSA:3.40.630.30 138 303 1.5E-27 T 29-03-2018 SMALA_RS14060 f44790f5bbccc6fcf37e84592f4ffe3f 308 Gene3D G3DSA:1.10.10.10 2 137 1.9E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS14060 f44790f5bbccc6fcf37e84592f4ffe3f 308 SUPERFAMILY SSF46785 9 137 1.09E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS16545 1fccd1963f396e2edc7303ff00fda458 402 Pfam PF08282 haloacid dehalogenase-like hydrolase 324 388 1.2E-7 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS16545 1fccd1963f396e2edc7303ff00fda458 402 Gene3D G3DSA:3.90.550.10 6 235 3.3E-32 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS16545 1fccd1963f396e2edc7303ff00fda458 402 Gene3D G3DSA:3.40.50.1000 243 402 1.3E-23 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS16545 1fccd1963f396e2edc7303ff00fda458 402 SUPERFAMILY SSF56784 249 397 5.61E-31 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS16545 1fccd1963f396e2edc7303ff00fda458 402 Pfam PF02348 Cytidylyltransferase 10 142 1.8E-21 T 29-03-2018 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|Reactome: R-HSA-4085001 SMALA_RS16545 1fccd1963f396e2edc7303ff00fda458 402 SUPERFAMILY SSF53448 8 232 1.13E-47 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS42055 5106793ed388adf55413d298cd2bb24d 82 SUPERFAMILY SSF47336 21 74 6.67E-6 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS42055 5106793ed388adf55413d298cd2bb24d 82 Gene3D G3DSA:1.10.1200.10 4 81 2.1E-5 T 29-03-2018 SMALA_RS42055 5106793ed388adf55413d298cd2bb24d 82 ProSitePatterns PS00012 Phosphopantetheine attachment site. 27 42 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS26795 8c326f493f54b249ed395f288f0843d8 458 Gene3D G3DSA:1.10.443.10 236 439 5.2E-23 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 SMALA_RS26795 8c326f493f54b249ed395f288f0843d8 458 SUPERFAMILY SSF56349 168 439 4.12E-25 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 SMALA_RS26795 8c326f493f54b249ed395f288f0843d8 458 Pfam PF00589 Phage integrase family 242 425 8.3E-6 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 SMALA_RS26795 8c326f493f54b249ed395f288f0843d8 458 Gene3D G3DSA:1.10.150.130 68 235 6.6E-18 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal SMALA_RS40995 b342bf3db18a467d1d2f4bbd6dc23293 317 Pfam PF13279 Thioesterase-like superfamily 187 295 2.3E-7 T 29-03-2018 SMALA_RS40995 b342bf3db18a467d1d2f4bbd6dc23293 317 SUPERFAMILY SSF54637 175 285 7.02E-9 T 29-03-2018 IPR029069 HotDog domain SMALA_RS40995 b342bf3db18a467d1d2f4bbd6dc23293 317 Gene3D G3DSA:3.10.129.10 171 312 2.9E-11 T 29-03-2018 SMALA_RS40995 b342bf3db18a467d1d2f4bbd6dc23293 317 Gene3D G3DSA:3.10.129.10 11 166 0.0025 T 29-03-2018 SMALA_RS06420 2b1a8636cb111f3f899932d3e1c45501 490 Pfam PF07690 Major Facilitator Superfamily 30 419 1.0E-51 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS06420 2b1a8636cb111f3f899932d3e1c45501 490 Gene3D G3DSA:1.20.1250.20 13 205 2.6E-33 T 29-03-2018 SMALA_RS06420 2b1a8636cb111f3f899932d3e1c45501 490 SUPERFAMILY SSF103473 258 468 3.66E-67 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS06420 2b1a8636cb111f3f899932d3e1c45501 490 SUPERFAMILY SSF103473 7 210 3.66E-67 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS06420 2b1a8636cb111f3f899932d3e1c45501 490 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 24 427 3.4E-85 T 29-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 SMALA_RS06420 2b1a8636cb111f3f899932d3e1c45501 490 Gene3D G3DSA:1.20.1250.20 269 483 6.9E-25 T 29-03-2018 SMALA_RS37990 f4fdfe85ccdc5c7a3868c7ea592d8390 231 SUPERFAMILY SSF52317 105 216 3.31E-32 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS37990 f4fdfe85ccdc5c7a3868c7ea592d8390 231 SUPERFAMILY SSF52317 4 77 3.31E-32 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS37990 f4fdfe85ccdc5c7a3868c7ea592d8390 231 Gene3D G3DSA:3.40.50.880 2 224 1.6E-47 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS37990 f4fdfe85ccdc5c7a3868c7ea592d8390 231 Pfam PF01965 DJ-1/PfpI family 118 197 1.6E-13 T 29-03-2018 IPR002818 DJ-1/PfpI SMALA_RS16180 431e670d8df4e2ec1c78a15075573a71 846 Pfam PF02687 FtsX-like permease family 747 838 1.1E-13 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 SMALA_RS16180 431e670d8df4e2ec1c78a15075573a71 846 Pfam PF02687 FtsX-like permease family 297 392 4.3E-15 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 SMALA_RS16180 431e670d8df4e2ec1c78a15075573a71 846 Pfam PF12704 MacB-like periplasmic core domain 17 236 3.1E-15 T 29-03-2018 IPR025857 MacB-like periplasmic core domain SMALA_RS16180 431e670d8df4e2ec1c78a15075573a71 846 Pfam PF12704 MacB-like periplasmic core domain 491 682 7.0E-14 T 29-03-2018 IPR025857 MacB-like periplasmic core domain SMALA_RS40050 8a2aeca331b1c56e9ccaa6e257cc1d0f 443 ProSitePatterns PS00216 Sugar transport proteins signature 1. 309 326 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMALA_RS40050 8a2aeca331b1c56e9ccaa6e257cc1d0f 443 Pfam PF07690 Major Facilitator Superfamily 61 385 1.0E-42 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS40050 8a2aeca331b1c56e9ccaa6e257cc1d0f 443 Gene3D G3DSA:1.20.1250.20 19 233 1.1E-22 T 29-03-2018 SMALA_RS40050 8a2aeca331b1c56e9ccaa6e257cc1d0f 443 SUPERFAMILY SSF103473 26 438 9.81E-69 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS40050 8a2aeca331b1c56e9ccaa6e257cc1d0f 443 Gene3D G3DSA:1.20.1250.20 234 443 7.6E-29 T 29-03-2018 SMALA_RS40050 8a2aeca331b1c56e9ccaa6e257cc1d0f 443 ProSitePatterns PS00217 Sugar transport proteins signature 2. 137 162 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMALA_RS03150 88e166963e883e50cb11fb5558637240 213 Gene3D G3DSA:3.30.530.20 1 157 1.0E-21 T 29-03-2018 IPR023393 START-like domain SMALA_RS03150 88e166963e883e50cb11fb5558637240 213 Pfam PF06240 Carbon monoxide dehydrogenase subunit G (CoxG) 7 142 2.6E-18 T 29-03-2018 IPR010419 Carbon monoxide dehydrogenase subunit G SMALA_RS03150 88e166963e883e50cb11fb5558637240 213 SUPERFAMILY SSF55961 1 145 2.96E-28 T 29-03-2018 SMALA_RS38585 a999c21b4680181fa593def7b4384ace 371 TIGRFAM TIGR00543 isochor_syn: isochorismate synthase 94 367 2.8E-81 T 29-03-2018 IPR004561 Isochorismate synthase GO:0008909|GO:0009058 KEGG: 00130+5.4.4.2|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6406 SMALA_RS38585 a999c21b4680181fa593def7b4384ace 371 SUPERFAMILY SSF56322 76 368 4.71E-83 T 29-03-2018 IPR005801 ADC synthase GO:0009058 SMALA_RS38585 a999c21b4680181fa593def7b4384ace 371 Gene3D G3DSA:3.60.120.10 45 370 2.7E-87 T 29-03-2018 IPR005801 ADC synthase GO:0009058 SMALA_RS38585 a999c21b4680181fa593def7b4384ace 371 Pfam PF00425 chorismate binding enzyme 110 360 1.2E-68 T 29-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal SMALA_RS32115 feacd7dc600fe6f1fda286653dd2823c 241 Gene3D G3DSA:3.40.50.1580 13 188 1.2E-23 T 29-03-2018 SMALA_RS32115 feacd7dc600fe6f1fda286653dd2823c 241 SUPERFAMILY SSF53167 11 187 2.49E-24 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 SMALA_RS32115 feacd7dc600fe6f1fda286653dd2823c 241 Pfam PF01048 Phosphorylase superfamily 36 183 7.4E-16 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 SMALA_RS05550 59e30c17b739ee8565713f612538a092 382 Pfam PF00155 Aminotransferase class I and II 57 367 6.3E-49 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMALA_RS05550 59e30c17b739ee8565713f612538a092 382 Gene3D G3DSA:3.90.1150.10 274 375 1.2E-19 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS05550 59e30c17b739ee8565713f612538a092 382 Gene3D G3DSA:3.40.640.10 58 273 1.2E-49 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS05550 59e30c17b739ee8565713f612538a092 382 SUPERFAMILY SSF53383 30 371 4.65E-86 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS00400 8a30fcb1e0add0e91fd5324de39361c7 409 Gene3D G3DSA:2.40.50.100 1 81 1.5E-7 T 29-03-2018 SMALA_RS00400 8a30fcb1e0add0e91fd5324de39361c7 409 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 26 55 - T 29-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 SMALA_RS00400 8a30fcb1e0add0e91fd5324de39361c7 409 SUPERFAMILY SSF51230 3 93 1.06E-13 T 29-03-2018 IPR011053 Single hybrid motif SMALA_RS00400 8a30fcb1e0add0e91fd5324de39361c7 409 SUPERFAMILY SSF52777 168 396 9.34E-38 T 29-03-2018 SMALA_RS00400 8a30fcb1e0add0e91fd5324de39361c7 409 Gene3D G3DSA:3.30.559.10 163 397 2.0E-36 T 29-03-2018 SMALA_RS00400 8a30fcb1e0add0e91fd5324de39361c7 409 Pfam PF00364 Biotin-requiring enzyme 4 73 1.5E-8 T 29-03-2018 IPR000089 Biotin/lipoyl attachment SMALA_RS00400 8a30fcb1e0add0e91fd5324de39361c7 409 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 177 396 5.3E-32 T 29-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 SMALA_RS04620 2f0e9ecac41a65180f80db66bb578a6b 384 Pfam PF01384 Phosphate transporter family 22 320 4.2E-81 T 29-03-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 SMALA_RS32790 145d523d26ecfb33ef60acdeeccf1de8 189 Pfam PF01323 DSBA-like thioredoxin domain 30 177 3.1E-23 T 29-03-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 SMALA_RS32790 145d523d26ecfb33ef60acdeeccf1de8 189 Gene3D G3DSA:3.40.30.10 14 181 3.2E-32 T 29-03-2018 SMALA_RS32790 145d523d26ecfb33ef60acdeeccf1de8 189 SUPERFAMILY SSF52833 23 178 1.05E-27 T 29-03-2018 IPR012336 Thioredoxin-like fold SMALA_RS35650 f2417c7789289a3765a28b52d472caeb 304 SUPERFAMILY SSF51621 9 252 4.32E-48 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SMALA_RS35650 f2417c7789289a3765a28b52d472caeb 304 Gene3D G3DSA:3.20.20.360 1 277 9.4E-50 T 29-03-2018 SMALA_RS35650 f2417c7789289a3765a28b52d472caeb 304 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 12 241 5.7E-32 T 29-03-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 SMALA_RS35650 f2417c7789289a3765a28b52d472caeb 304 PIRSF PIRSF015582 1 303 3.0E-69 T 29-03-2018 IPR011206 Citrate lyase beta subunit-like SMALA_RS06665 9d77628cb6592d8572ab4ddaecab995c 249 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 245 3.2E-63 T 29-03-2018 SMALA_RS06665 9d77628cb6592d8572ab4ddaecab995c 249 Gene3D G3DSA:3.40.50.720 2 248 1.4E-72 T 29-03-2018 SMALA_RS06665 9d77628cb6592d8572ab4ddaecab995c 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 2.7E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS06665 9d77628cb6592d8572ab4ddaecab995c 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 2.7E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS06665 9d77628cb6592d8572ab4ddaecab995c 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 2.7E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS06665 9d77628cb6592d8572ab4ddaecab995c 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 2.7E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS06665 9d77628cb6592d8572ab4ddaecab995c 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 2.7E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS06665 9d77628cb6592d8572ab4ddaecab995c 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 2.7E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS06665 9d77628cb6592d8572ab4ddaecab995c 249 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 182 9.7E-5 T 29-03-2018 SMALA_RS06665 9d77628cb6592d8572ab4ddaecab995c 249 SUPERFAMILY SSF51735 5 246 7.14E-76 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS06665 9d77628cb6592d8572ab4ddaecab995c 249 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 138 166 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMALA_RS08145 756c909d092a5f05c9ba6d38326b2f70 346 Gene3D G3DSA:3.40.190.10 104 239 1.7E-4 T 29-03-2018 SMALA_RS08145 756c909d092a5f05c9ba6d38326b2f70 346 SUPERFAMILY SSF46785 17 117 9.68E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS08145 756c909d092a5f05c9ba6d38326b2f70 346 Gene3D G3DSA:1.10.10.10 8 103 9.1E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS08145 756c909d092a5f05c9ba6d38326b2f70 346 SUPERFAMILY SSF53850 136 265 8.15E-7 T 29-03-2018 SMALA_RS08145 756c909d092a5f05c9ba6d38326b2f70 346 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 19 83 2.9E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS11665 c861c0e30a395240342017772d2050f3 592 Pfam PF09423 PhoD-like phosphatase 144 480 2.6E-11 T 29-03-2018 IPR018946 Alkaline phosphatase D-related SMALA_RS11665 c861c0e30a395240342017772d2050f3 592 SUPERFAMILY SSF56300 277 345 3.57E-9 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SMALA_RS11665 c861c0e30a395240342017772d2050f3 592 SUPERFAMILY SSF56300 106 227 3.57E-9 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SMALA_RS11665 c861c0e30a395240342017772d2050f3 592 Gene3D G3DSA:3.60.21.10 104 574 5.7E-27 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SMALA_RS27735 4eae4082f61d6590a1605017536713c0 265 Gene3D G3DSA:1.10.357.10 89 210 5.4E-9 T 29-03-2018 SMALA_RS27735 4eae4082f61d6590a1605017536713c0 265 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 50 2.2E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS27735 4eae4082f61d6590a1605017536713c0 265 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 57 80 2.2E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS27735 4eae4082f61d6590a1605017536713c0 265 SUPERFAMILY SSF48498 102 208 5.19E-18 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS27735 4eae4082f61d6590a1605017536713c0 265 SUPERFAMILY SSF46689 23 104 9.93E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS27735 4eae4082f61d6590a1605017536713c0 265 Gene3D G3DSA:1.10.10.60 13 58 1.3E-13 T 29-03-2018 SMALA_RS27735 4eae4082f61d6590a1605017536713c0 265 Pfam PF00440 Bacterial regulatory proteins, tetR family 37 78 6.8E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS27735 4eae4082f61d6590a1605017536713c0 265 Gene3D G3DSA:1.10.260.40 59 88 6.1E-8 T 29-03-2018 SMALA_RS32970 c511f79664211c3e70ad278b80b9ec27 206 SMART SM00448 2 115 1.9E-29 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS32970 c511f79664211c3e70ad278b80b9ec27 206 Gene3D G3DSA:3.40.50.2300 1 126 2.5E-34 T 29-03-2018 SMALA_RS32970 c511f79664211c3e70ad278b80b9ec27 206 SUPERFAMILY SSF46894 129 206 2.38E-21 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS32970 c511f79664211c3e70ad278b80b9ec27 206 Pfam PF00196 Bacterial regulatory proteins, luxR family 145 199 1.5E-16 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS32970 c511f79664211c3e70ad278b80b9ec27 206 Pfam PF00072 Response regulator receiver domain 4 116 5.8E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS32970 c511f79664211c3e70ad278b80b9ec27 206 ProSitePatterns PS00622 LuxR-type HTH domain signature. 160 187 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS32970 c511f79664211c3e70ad278b80b9ec27 206 SUPERFAMILY SSF52172 2 133 3.98E-33 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS32970 c511f79664211c3e70ad278b80b9ec27 206 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 176 188 9.1E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS32970 c511f79664211c3e70ad278b80b9ec27 206 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 146 160 9.1E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS32970 c511f79664211c3e70ad278b80b9ec27 206 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 160 176 9.1E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS32970 c511f79664211c3e70ad278b80b9ec27 206 SMART SM00421 143 200 5.7E-23 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS32970 c511f79664211c3e70ad278b80b9ec27 206 Gene3D G3DSA:1.10.10.10 127 206 2.1E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS18465 6c44d3237a7b0c4612f887716ad6139c 399 Pfam PF00145 C-5 cytosine-specific DNA methylase 7 173 2.1E-43 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS18465 6c44d3237a7b0c4612f887716ad6139c 399 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 7 23 2.6E-14 T 29-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 SMALA_RS18465 6c44d3237a7b0c4612f887716ad6139c 399 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 106 120 2.6E-14 T 29-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 SMALA_RS18465 6c44d3237a7b0c4612f887716ad6139c 399 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 152 165 2.6E-14 T 29-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 SMALA_RS18465 6c44d3237a7b0c4612f887716ad6139c 399 SUPERFAMILY SSF53335 3 293 4.08E-58 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS18465 6c44d3237a7b0c4612f887716ad6139c 399 Gene3D G3DSA:3.40.50.150 1 191 5.1E-50 T 29-03-2018 SMALA_RS18465 6c44d3237a7b0c4612f887716ad6139c 399 ProSitePatterns PS00094 C-5 cytosine-specific DNA methylases active site. 67 79 - T 29-03-2018 IPR018117 DNA methylase, C-5 cytosine-specific, active site KEGG: 00270+2.1.1.37|Reactome: R-HSA-212300|Reactome: R-HSA-5334118 SMALA_RS18465 6c44d3237a7b0c4612f887716ad6139c 399 TIGRFAM TIGR00675 dcm: DNA (cytosine-5-)-methyltransferase 9 169 4.5E-39 T 29-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 SMALA_RS12440 acbbac26c2d1a4de0fc39a03c719dfc2 121 Gene3D G3DSA:1.10.10.10 6 100 6.7E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS12440 acbbac26c2d1a4de0fc39a03c719dfc2 121 Pfam PF05331 Protein of unknown function (DUF742) 8 119 9.7E-30 T 29-03-2018 IPR007995 Protein of unknown function DUF742 SMALA_RS29255 efcd2595ef664e6e3c53f9f42eb77829 222 Pfam PF02080 TrkA-C domain 150 213 1.0E-9 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 SMALA_RS29255 efcd2595ef664e6e3c53f9f42eb77829 222 SUPERFAMILY SSF116726 139 210 1.28E-8 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 SMALA_RS29255 efcd2595ef664e6e3c53f9f42eb77829 222 Gene3D G3DSA:3.30.70.1450 141 216 6.4E-11 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 SMALA_RS29255 efcd2595ef664e6e3c53f9f42eb77829 222 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 2.3E-8 T 29-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 SMALA_RS29255 efcd2595ef664e6e3c53f9f42eb77829 222 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 2.3E-8 T 29-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 SMALA_RS29255 efcd2595ef664e6e3c53f9f42eb77829 222 PRINTS PR00335 TrkA potassium uptake protein signature 73 87 2.3E-8 T 29-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 SMALA_RS29255 efcd2595ef664e6e3c53f9f42eb77829 222 PRINTS PR00335 TrkA potassium uptake protein signature 60 70 2.3E-8 T 29-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 SMALA_RS29255 efcd2595ef664e6e3c53f9f42eb77829 222 Pfam PF02254 TrkA-N domain 3 116 1.8E-25 T 29-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 SMALA_RS29255 efcd2595ef664e6e3c53f9f42eb77829 222 Gene3D G3DSA:3.40.50.720 1 133 4.0E-21 T 29-03-2018 SMALA_RS29255 efcd2595ef664e6e3c53f9f42eb77829 222 SUPERFAMILY SSF51735 1 140 9.84E-30 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS17185 4065bfd548ed88e3bed1f3e6ef3b175b 519 Gene3D G3DSA:3.30.450.20 43 171 2.9E-23 T 29-03-2018 SMALA_RS17185 4065bfd548ed88e3bed1f3e6ef3b175b 519 SUPERFAMILY SSF55785 48 156 2.62E-18 T 29-03-2018 IPR000014 PAS domain SMALA_RS17185 4065bfd548ed88e3bed1f3e6ef3b175b 519 Gene3D G3DSA:3.30.450.20 172 329 2.0E-13 T 29-03-2018 SMALA_RS17185 4065bfd548ed88e3bed1f3e6ef3b175b 519 Gene3D G3DSA:3.30.450.40 330 518 4.9E-16 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS17185 4065bfd548ed88e3bed1f3e6ef3b175b 519 SUPERFAMILY SSF55781 416 515 6.67E-7 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS17185 4065bfd548ed88e3bed1f3e6ef3b175b 519 SMART SM00091 48 116 3.0E-7 T 29-03-2018 IPR000014 PAS domain SMALA_RS17185 4065bfd548ed88e3bed1f3e6ef3b175b 519 SMART SM00091 172 237 2.0 T 29-03-2018 IPR000014 PAS domain SMALA_RS17185 4065bfd548ed88e3bed1f3e6ef3b175b 519 Pfam PF00989 PAS fold 49 159 4.5E-11 T 29-03-2018 IPR013767 PAS fold GO:0006355 SMALA_RS17185 4065bfd548ed88e3bed1f3e6ef3b175b 519 SUPERFAMILY SSF55785 162 253 1.94E-6 T 29-03-2018 IPR000014 PAS domain SMALA_RS17185 4065bfd548ed88e3bed1f3e6ef3b175b 519 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 48 169 9.2E-14 T 29-03-2018 IPR000014 PAS domain SMALA_RS09595 b47770a230cf78064519a718df16c0c8 339 Pfam PF01933 Uncharacterised protein family UPF0052 24 289 5.3E-72 T 29-03-2018 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 SMALA_RS09595 b47770a230cf78064519a718df16c0c8 339 TIGRFAM TIGR01826 CofD_related: conserved hypothetical protein 24 290 1.0E-84 T 29-03-2018 IPR010119 Gluconeogenesis factor SMALA_RS09595 b47770a230cf78064519a718df16c0c8 339 SUPERFAMILY SSF142338 21 325 1.83E-84 T 29-03-2018 SMALA_RS09595 b47770a230cf78064519a718df16c0c8 339 Hamap MF_00973 Gluconeogenesis factor. 20 331 32.452 T 29-03-2018 IPR010119 Gluconeogenesis factor SMALA_RS09595 b47770a230cf78064519a718df16c0c8 339 Gene3D G3DSA:3.40.50.10680 105 333 1.6E-51 T 29-03-2018 SMALA_RS28430 8983cd1fe16cb79291f4e14c217f2507 281 SUPERFAMILY SSF55729 8 276 6.62E-21 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS28430 8983cd1fe16cb79291f4e14c217f2507 281 PIRSF PIRSF021603 2 281 1.5E-133 T 29-03-2018 IPR016794 Uncharacterised conserved protein UCP21603, acetyltransferase-like SMALA_RS28430 8983cd1fe16cb79291f4e14c217f2507 281 Gene3D G3DSA:3.40.630.30 3 279 4.7E-25 T 29-03-2018 SMALA_RS28430 8983cd1fe16cb79291f4e14c217f2507 281 Pfam PF13312 Domain of unknown function (DUF4081) 48 152 1.4E-42 T 29-03-2018 IPR025289 Domain of unknown function DUF4081 SMALA_RS28430 8983cd1fe16cb79291f4e14c217f2507 281 Pfam PF00583 Acetyltransferase (GNAT) family 211 270 3.5E-9 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SMALA_RS33060 edc2644e2e262caa0628d781d6a7c440 376 SUPERFAMILY SSF53092 5 145 6.15E-14 T 29-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal SMALA_RS33060 edc2644e2e262caa0628d781d6a7c440 376 SUPERFAMILY SSF55920 145 374 1.83E-58 T 29-03-2018 IPR000994 Peptidase M24 SMALA_RS33060 edc2644e2e262caa0628d781d6a7c440 376 Pfam PF00557 Metallopeptidase family M24 154 356 3.0E-44 T 29-03-2018 IPR000994 Peptidase M24 SMALA_RS33060 edc2644e2e262caa0628d781d6a7c440 376 Gene3D G3DSA:3.90.230.10 145 376 1.9E-56 T 29-03-2018 SMALA_RS33060 edc2644e2e262caa0628d781d6a7c440 376 Pfam PF01321 Creatinase/Prolidase N-terminal domain 8 146 7.5E-10 T 29-03-2018 IPR000587 Creatinase, N-terminal GO:0016787 SMALA_RS33060 edc2644e2e262caa0628d781d6a7c440 376 Gene3D G3DSA:3.40.350.10 3 144 1.3E-15 T 29-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal SMALA_RS20245 cf0c534f33ab4cb5202de9b24efaa813 138 SUPERFAMILY SSF55874 36 118 3.87E-9 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS20245 cf0c534f33ab4cb5202de9b24efaa813 138 Gene3D G3DSA:3.30.565.10 11 134 6.6E-13 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS15920 618a39035d4b283e7c71877c6590f989 563 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 442 533 4.5E-12 T 29-03-2018 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain SMALA_RS15920 618a39035d4b283e7c71877c6590f989 563 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 168 331 6.6E-41 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain SMALA_RS15920 618a39035d4b283e7c71877c6590f989 563 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 168 331 7.2E-45 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain SMALA_RS22445 5aed0d4b25546fc1a73c2e4b07e1a4c0 187 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 1 158 24.538 T 29-03-2018 IPR022973 Ribosomal protein L10 SMALA_RS22445 5aed0d4b25546fc1a73c2e4b07e1a4c0 187 SUPERFAMILY SSF160369 2 168 6.54E-51 T 29-03-2018 SMALA_RS22445 5aed0d4b25546fc1a73c2e4b07e1a4c0 187 Pfam PF00466 Ribosomal protein L10 3 98 4.7E-26 T 29-03-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 SMALA_RS22445 5aed0d4b25546fc1a73c2e4b07e1a4c0 187 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 60 140 0.002 T 29-03-2018 SMALA_RS24225 b0576738f3dabdbb0276bc72c03c3d2b 120 Gene3D G3DSA:3.30.70.100 1 99 7.7E-24 T 29-03-2018 SMALA_RS24225 b0576738f3dabdbb0276bc72c03c3d2b 120 Pfam PF07045 Domain of unknown function (DUF1330) 4 97 4.8E-19 T 29-03-2018 IPR010753 Domain of unknown function DUF1330 SMALA_RS24225 b0576738f3dabdbb0276bc72c03c3d2b 120 SUPERFAMILY SSF54909 1 97 1.66E-18 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel SMALA_RS35425 032e69cbc9a09905e44478384a56889b 623 SMART SM00956 420 526 4.4E-44 T 29-03-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 SMALA_RS35425 032e69cbc9a09905e44478384a56889b 623 Pfam PF00570 HRDC domain 557 620 1.0E-22 T 29-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 SMALA_RS35425 032e69cbc9a09905e44478384a56889b 623 Pfam PF00271 Helicase conserved C-terminal domain 233 339 2.8E-16 T 29-03-2018 IPR001650 Helicase, C-terminal SMALA_RS35425 032e69cbc9a09905e44478384a56889b 623 Pfam PF16124 RecQ zinc-binding 352 413 7.3E-17 T 29-03-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain SMALA_RS35425 032e69cbc9a09905e44478384a56889b 623 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 23 475 6.3E-152 T 29-03-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 SMALA_RS35425 032e69cbc9a09905e44478384a56889b 623 SMART SM00490 259 340 1.3E-22 T 29-03-2018 IPR001650 Helicase, C-terminal SMALA_RS35425 032e69cbc9a09905e44478384a56889b 623 SUPERFAMILY SSF47819 549 622 2.62E-21 T 29-03-2018 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 SMALA_RS35425 032e69cbc9a09905e44478384a56889b 623 SUPERFAMILY SSF52540 216 472 4.62E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS35425 032e69cbc9a09905e44478384a56889b 623 Gene3D G3DSA:1.10.10.10 363 534 7.9E-45 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS35425 032e69cbc9a09905e44478384a56889b 623 Pfam PF09382 RQC domain 415 528 2.9E-33 T 29-03-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 SMALA_RS35425 032e69cbc9a09905e44478384a56889b 623 SUPERFAMILY SSF52540 19 206 1.3E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS35425 032e69cbc9a09905e44478384a56889b 623 Gene3D G3DSA:3.40.50.300 17 216 2.0E-32 T 29-03-2018 SMALA_RS35425 032e69cbc9a09905e44478384a56889b 623 Pfam PF00270 DEAD/DEAH box helicase 38 194 1.5E-17 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 SMALA_RS35425 032e69cbc9a09905e44478384a56889b 623 SMART SM00487 30 224 8.0E-28 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain SMALA_RS35425 032e69cbc9a09905e44478384a56889b 623 Gene3D G3DSA:3.40.50.300 217 362 6.9E-28 T 29-03-2018 SMALA_RS35425 032e69cbc9a09905e44478384a56889b 623 TIGRFAM TIGR01389 recQ: ATP-dependent DNA helicase RecQ 23 620 6.4E-231 T 29-03-2018 IPR006293 DNA helicase, ATP-dependent, RecQ type, bacterial GO:0004003|GO:0006310|GO:0009432 SMALA_RS35425 032e69cbc9a09905e44478384a56889b 623 Gene3D G3DSA:1.10.150.80 535 623 1.2E-24 T 29-03-2018 SMALA_RS35425 032e69cbc9a09905e44478384a56889b 623 SMART SM00341 551 620 1.4E-11 T 29-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 SMALA_RS16135 a1866426bd0dda9f2cd56cc7c34ceadc 461 Pfam PF00571 CBS domain 409 457 1.7E-4 T 29-03-2018 IPR000644 CBS domain SMALA_RS16135 a1866426bd0dda9f2cd56cc7c34ceadc 461 Pfam PF00571 CBS domain 339 394 5.6E-5 T 29-03-2018 IPR000644 CBS domain SMALA_RS16135 a1866426bd0dda9f2cd56cc7c34ceadc 461 SUPERFAMILY SSF54631 339 458 1.52E-15 T 29-03-2018 SMALA_RS16135 a1866426bd0dda9f2cd56cc7c34ceadc 461 SMART SM00116 412 457 3.2 T 29-03-2018 IPR000644 CBS domain SMALA_RS16135 a1866426bd0dda9f2cd56cc7c34ceadc 461 SMART SM00116 339 395 0.092 T 29-03-2018 IPR000644 CBS domain SMALA_RS16135 a1866426bd0dda9f2cd56cc7c34ceadc 461 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 29-03-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 SMALA_RS16135 a1866426bd0dda9f2cd56cc7c34ceadc 461 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 11 296 4.9E-71 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMALA_RS16135 a1866426bd0dda9f2cd56cc7c34ceadc 461 Gene3D G3DSA:3.10.580.10 317 461 2.5E-20 T 29-03-2018 SMALA_RS16135 a1866426bd0dda9f2cd56cc7c34ceadc 461 Gene3D G3DSA:3.40.50.1100 146 310 1.1E-54 T 29-03-2018 SMALA_RS16135 a1866426bd0dda9f2cd56cc7c34ceadc 461 SUPERFAMILY SSF53686 2 317 4.19E-100 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMALA_RS16135 a1866426bd0dda9f2cd56cc7c34ceadc 461 Gene3D G3DSA:3.40.50.1100 38 145 1.2E-39 T 29-03-2018 SMALA_RS16135 a1866426bd0dda9f2cd56cc7c34ceadc 461 TIGRFAM TIGR01137 cysta_beta: cystathionine beta-synthase 5 457 3.0E-211 T 29-03-2018 IPR005857 Cystathionine beta-synthase GO:0004122|GO:0005737|GO:0019343 KEGG: 00260+4.2.1.22|KEGG: 00270+4.2.1.22|MetaCyc: PWY-801 SMALA_RS04690 b3e66e06c14d9dfbd90795536344b178 743 SUPERFAMILY SSF53067 414 727 2.9E-42 T 29-03-2018 SMALA_RS04690 b3e66e06c14d9dfbd90795536344b178 743 Gene3D G3DSA:1.10.10.10 56 93 3.5E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS04690 b3e66e06c14d9dfbd90795536344b178 743 Gene3D G3DSA:1.10.10.10 341 412 3.3E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS04690 b3e66e06c14d9dfbd90795536344b178 743 Gene3D G3DSA:3.30.420.40 413 558 2.5E-41 T 29-03-2018 SMALA_RS04690 b3e66e06c14d9dfbd90795536344b178 743 Gene3D G3DSA:1.10.10.60 23 55 1.0E-8 T 29-03-2018 SMALA_RS04690 b3e66e06c14d9dfbd90795536344b178 743 Gene3D G3DSA:3.30.420.40 559 709 1.4E-23 T 29-03-2018 SMALA_RS04690 b3e66e06c14d9dfbd90795536344b178 743 Pfam PF13551 Winged helix-turn helix 32 90 6.0E-15 T 29-03-2018 SMALA_RS04690 b3e66e06c14d9dfbd90795536344b178 743 Pfam PF00480 ROK family 424 723 1.9E-35 T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 SMALA_RS04690 b3e66e06c14d9dfbd90795536344b178 743 SUPERFAMILY SSF46785 346 404 7.66E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS04690 b3e66e06c14d9dfbd90795536344b178 743 SUPERFAMILY SSF46689 28 91 4.84E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS01555 267489df7ad16adf735fd7e71d22cfec 1545 SUPERFAMILY SSF52151 748 850 2.17E-27 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS01555 267489df7ad16adf735fd7e71d22cfec 1545 SUPERFAMILY SSF52151 574 676 2.17E-27 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS01555 267489df7ad16adf735fd7e71d22cfec 1545 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 212 228 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS01555 267489df7ad16adf735fd7e71d22cfec 1545 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 307 427 1.8E-33 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS01555 267489df7ad16adf735fd7e71d22cfec 1545 Pfam PF14765 Polyketide synthase dehydratase 980 1249 7.8E-17 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS01555 267489df7ad16adf735fd7e71d22cfec 1545 Gene3D G3DSA:3.40.47.10 315 478 1.6E-50 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS01555 267489df7ad16adf735fd7e71d22cfec 1545 Gene3D G3DSA:3.90.470.20 1268 1421 5.5E-17 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 SMALA_RS01555 267489df7ad16adf735fd7e71d22cfec 1545 Gene3D G3DSA:3.40.366.10 562 857 1.3E-41 T 29-03-2018 SMALA_RS01555 267489df7ad16adf735fd7e71d22cfec 1545 SMART SM00825 Beta-ketoacyl synthase 14 476 6.2E-103 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS01555 267489df7ad16adf735fd7e71d22cfec 1545 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 578 855 3.1E-12 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS01555 267489df7ad16adf735fd7e71d22cfec 1545 Gene3D G3DSA:3.10.129.10 976 1093 2.1E-4 T 29-03-2018 SMALA_RS01555 267489df7ad16adf735fd7e71d22cfec 1545 SUPERFAMILY SSF53901 451 472 5.66E-73 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS01555 267489df7ad16adf735fd7e71d22cfec 1545 SUPERFAMILY SSF53901 194 423 5.66E-73 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS01555 267489df7ad16adf735fd7e71d22cfec 1545 SUPERFAMILY SSF53901 9 135 5.66E-73 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS01555 267489df7ad16adf735fd7e71d22cfec 1545 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 432 509 1.4E-9 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS01555 267489df7ad16adf735fd7e71d22cfec 1545 Gene3D G3DSA:3.10.129.10 1094 1238 0.0027 T 29-03-2018 SMALA_RS01555 267489df7ad16adf735fd7e71d22cfec 1545 Gene3D G3DSA:3.40.47.10 4 310 5.5E-72 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS01555 267489df7ad16adf735fd7e71d22cfec 1545 SUPERFAMILY SSF55048 683 745 2.35E-5 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS01555 267489df7ad16adf735fd7e71d22cfec 1545 Pfam PF00698 Acyl transferase domain 622 827 4.3E-13 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS01555 267489df7ad16adf735fd7e71d22cfec 1545 SUPERFAMILY SSF56214 1283 1377 8.63E-10 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 SMALA_RS01555 267489df7ad16adf735fd7e71d22cfec 1545 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 13 299 2.6E-60 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS17695 29943a2256820cc460548299be657f4f 226 Gene3D G3DSA:1.10.10.10 118 226 3.1E-35 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS17695 29943a2256820cc460548299be657f4f 226 Gene3D G3DSA:3.40.50.2300 1 117 1.0E-36 T 29-03-2018 SMALA_RS17695 29943a2256820cc460548299be657f4f 226 SUPERFAMILY SSF52172 3 124 2.7E-41 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS17695 29943a2256820cc460548299be657f4f 226 SUPERFAMILY SSF46894 125 225 1.36E-31 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS17695 29943a2256820cc460548299be657f4f 226 Pfam PF00072 Response regulator receiver domain 4 113 1.0E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS17695 29943a2256820cc460548299be657f4f 226 SMART SM00448 2 112 6.4E-45 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS17695 29943a2256820cc460548299be657f4f 226 SMART SM00862 148 224 7.5E-30 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS17695 29943a2256820cc460548299be657f4f 226 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 224 1.3E-27 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS30595 491747b5a1525c1526c6d914595cb50b 142 SUPERFAMILY SSF53933 48 139 3.4E-37 T 29-03-2018 IPR016191 Ribonuclease/ribotoxin GO:0003723|GO:0004540 SMALA_RS30595 491747b5a1525c1526c6d914595cb50b 142 Gene3D G3DSA:3.10.450.30 47 142 5.6E-34 T 29-03-2018 SMALA_RS30595 491747b5a1525c1526c6d914595cb50b 142 Pfam PF00545 ribonuclease 57 136 4.0E-28 T 29-03-2018 IPR000026 Guanine-specific ribonuclease N1/T1/U2 GO:0003723|GO:0004521 SMALA_RS42035 22b67d64f910d85a2d033f968e4c47ce 414 Gene3D G3DSA:3.90.1150.10 300 390 3.7E-10 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS42035 22b67d64f910d85a2d033f968e4c47ce 414 Pfam PF00155 Aminotransferase class I and II 66 377 5.1E-57 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMALA_RS42035 22b67d64f910d85a2d033f968e4c47ce 414 Gene3D G3DSA:3.40.640.10 60 299 8.5E-61 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS42035 22b67d64f910d85a2d033f968e4c47ce 414 SUPERFAMILY SSF53383 17 390 1.33E-90 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS42035 22b67d64f910d85a2d033f968e4c47ce 414 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 165 189 7.2E-13 T 29-03-2018 SMALA_RS42035 22b67d64f910d85a2d033f968e4c47ce 414 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 231 255 7.2E-13 T 29-03-2018 SMALA_RS42035 22b67d64f910d85a2d033f968e4c47ce 414 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 124 145 7.2E-13 T 29-03-2018 SMALA_RS42035 22b67d64f910d85a2d033f968e4c47ce 414 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 102 122 7.2E-13 T 29-03-2018 SMALA_RS42035 22b67d64f910d85a2d033f968e4c47ce 414 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 237 250 - T 29-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 SMALA_RS37935 79607e4201140338f81ec77f965599e0 235 Pfam PF00805 Pentapeptide repeats (8 copies) 132 167 3.0E-8 T 29-03-2018 IPR001646 Pentapeptide repeat SMALA_RS37935 79607e4201140338f81ec77f965599e0 235 Pfam PF00805 Pentapeptide repeats (8 copies) 85 124 5.1E-12 T 29-03-2018 IPR001646 Pentapeptide repeat SMALA_RS37935 79607e4201140338f81ec77f965599e0 235 Gene3D G3DSA:2.160.10.20 37 121 2.1E-16 T 29-03-2018 SMALA_RS37935 79607e4201140338f81ec77f965599e0 235 Gene3D G3DSA:3.30.1120.50 122 142 4.4E-8 T 29-03-2018 SMALA_RS37935 79607e4201140338f81ec77f965599e0 235 Gene3D G3DSA:2.160.10.20 143 210 3.0E-14 T 29-03-2018 SMALA_RS37935 79607e4201140338f81ec77f965599e0 235 SUPERFAMILY SSF141571 40 199 5.36E-33 T 29-03-2018 SMALA_RS21830 82a341f4b43e3556fb6b8fceaeefa291 329 SUPERFAMILY SSF53850 15 229 3.08E-63 T 29-03-2018 SMALA_RS21830 82a341f4b43e3556fb6b8fceaeefa291 329 Gene3D G3DSA:3.40.190.10 8 114 8.4E-36 T 29-03-2018 SMALA_RS21830 82a341f4b43e3556fb6b8fceaeefa291 329 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 15 318 34.958 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMALA_RS21830 82a341f4b43e3556fb6b8fceaeefa291 329 PRINTS PR00151 Porphobilinogen deaminase signature 84 103 2.8E-19 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMALA_RS21830 82a341f4b43e3556fb6b8fceaeefa291 329 PRINTS PR00151 Porphobilinogen deaminase signature 155 172 2.8E-19 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMALA_RS21830 82a341f4b43e3556fb6b8fceaeefa291 329 PRINTS PR00151 Porphobilinogen deaminase signature 242 259 2.8E-19 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMALA_RS21830 82a341f4b43e3556fb6b8fceaeefa291 329 PRINTS PR00151 Porphobilinogen deaminase signature 53 73 2.8E-19 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMALA_RS21830 82a341f4b43e3556fb6b8fceaeefa291 329 Gene3D G3DSA:3.30.160.40 234 325 2.2E-22 T 29-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMALA_RS21830 82a341f4b43e3556fb6b8fceaeefa291 329 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 16 318 2.5E-85 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMALA_RS21830 82a341f4b43e3556fb6b8fceaeefa291 329 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 239 316 1.5E-16 T 29-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMALA_RS21830 82a341f4b43e3556fb6b8fceaeefa291 329 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 243 259 - T 29-03-2018 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMALA_RS21830 82a341f4b43e3556fb6b8fceaeefa291 329 Gene3D G3DSA:3.40.190.10 115 211 1.4E-32 T 29-03-2018 SMALA_RS21830 82a341f4b43e3556fb6b8fceaeefa291 329 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 16 222 6.4E-66 T 29-03-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMALA_RS21830 82a341f4b43e3556fb6b8fceaeefa291 329 PIRSF PIRSF001438 3 329 3.6E-107 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMALA_RS21830 82a341f4b43e3556fb6b8fceaeefa291 329 SUPERFAMILY SSF54782 232 326 2.22E-18 T 29-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMALA_RS22075 8161e3c5c7cb60e5f5b4d60f35ed94f7 149 SUPERFAMILY SSF51338 1 63 2.38E-14 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS22075 8161e3c5c7cb60e5f5b4d60f35ed94f7 149 Gene3D G3DSA:2.30.40.10 2 64 1.4E-16 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS38890 92122793d4d60b353b1bc62274abbd36 193 Gene3D G3DSA:1.10.357.10 6 192 6.2E-31 T 29-03-2018 SMALA_RS38890 92122793d4d60b353b1bc62274abbd36 193 SUPERFAMILY SSF46689 9 88 3.29E-18 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS38890 92122793d4d60b353b1bc62274abbd36 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 62 2.7E-13 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS38890 92122793d4d60b353b1bc62274abbd36 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 3.7E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS38890 92122793d4d60b353b1bc62274abbd36 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 3.7E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS02145 7980116ba22a6c294a66e280851754c2 351 Pfam PF03099 Biotin/lipoate A/B protein ligase family 159 265 4.7E-7 T 29-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 SMALA_RS02145 7980116ba22a6c294a66e280851754c2 351 SUPERFAMILY SSF55681 92 347 7.1E-68 T 29-03-2018 SMALA_RS02145 7980116ba22a6c294a66e280851754c2 351 Gene3D G3DSA:3.30.930.10 88 343 2.6E-57 T 29-03-2018 SMALA_RS02145 7980116ba22a6c294a66e280851754c2 351 Gene3D G3DSA:3.30.390.50 1 87 2.9E-27 T 29-03-2018 SMALA_RS11495 68dc1c2be0d4f86c2d201e5f62cc6ebb 389 PIRSF PIRSF000429 1 389 3.2E-113 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 SMALA_RS11495 68dc1c2be0d4f86c2d201e5f62cc6ebb 389 SUPERFAMILY SSF53901 5 266 2.41E-61 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS11495 68dc1c2be0d4f86c2d201e5f62cc6ebb 389 SUPERFAMILY SSF53901 267 388 2.19E-38 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS11495 68dc1c2be0d4f86c2d201e5f62cc6ebb 389 ProSitePatterns PS00099 Thiolases active site. 370 383 - T 29-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 SMALA_RS11495 68dc1c2be0d4f86c2d201e5f62cc6ebb 389 Pfam PF00108 Thiolase, N-terminal domain 6 257 4.1E-51 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 SMALA_RS11495 68dc1c2be0d4f86c2d201e5f62cc6ebb 389 Gene3D G3DSA:3.40.47.10 2 260 9.9E-46 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS11495 68dc1c2be0d4f86c2d201e5f62cc6ebb 389 ProSitePatterns PS00737 Thiolases signature 2. 335 351 - T 29-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 SMALA_RS11495 68dc1c2be0d4f86c2d201e5f62cc6ebb 389 Gene3D G3DSA:3.40.47.10 261 386 6.5E-29 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS11495 68dc1c2be0d4f86c2d201e5f62cc6ebb 389 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 7 387 1.3E-114 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 SMALA_RS11495 68dc1c2be0d4f86c2d201e5f62cc6ebb 389 Pfam PF02803 Thiolase, C-terminal domain 267 388 3.3E-41 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 SMALA_RS10070 c75eb478f817e17127ce9b87381b0f37 372 Gene3D G3DSA:3.40.640.10 41 291 9.0E-45 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS10070 c75eb478f817e17127ce9b87381b0f37 372 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 8 367 54.048 T 29-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 SMALA_RS10070 c75eb478f817e17127ce9b87381b0f37 372 Pfam PF00155 Aminotransferase class I and II 28 363 1.9E-62 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMALA_RS10070 c75eb478f817e17127ce9b87381b0f37 372 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 10 365 5.8E-93 T 29-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 SMALA_RS10070 c75eb478f817e17127ce9b87381b0f37 372 Gene3D G3DSA:3.90.1150.10 292 368 9.1E-16 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS10070 c75eb478f817e17127ce9b87381b0f37 372 SUPERFAMILY SSF53383 27 366 1.65E-75 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS10070 c75eb478f817e17127ce9b87381b0f37 372 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 230 239 - T 29-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 SMALA_RS05150 62148257c4e00a8119022faae4f5e54a 174 Pfam PF03625 Domain of unknown function DUF302 91 131 1.8E-5 T 29-03-2018 IPR005180 Domain of unknown function DUF302 SMALA_RS05150 62148257c4e00a8119022faae4f5e54a 174 SUPERFAMILY SSF103247 42 158 2.22E-15 T 29-03-2018 IPR005180 Domain of unknown function DUF302 SMALA_RS05150 62148257c4e00a8119022faae4f5e54a 174 Gene3D G3DSA:3.30.310.70 37 160 9.2E-22 T 29-03-2018 IPR005180 Domain of unknown function DUF302 SMALA_RS40380 071d48f75dabf79c1e2700c56017860f 310 Pfam PF00701 Dihydrodipicolinate synthetase family 33 298 2.4E-51 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SMALA_RS40380 071d48f75dabf79c1e2700c56017860f 310 SUPERFAMILY SSF51569 10 300 7.01E-81 T 29-03-2018 SMALA_RS40380 071d48f75dabf79c1e2700c56017860f 310 PRINTS PR00146 Dihydrodipicolinate synthase signature 50 71 2.6E-7 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SMALA_RS40380 071d48f75dabf79c1e2700c56017860f 310 PRINTS PR00146 Dihydrodipicolinate synthase signature 142 159 2.6E-7 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SMALA_RS40380 071d48f75dabf79c1e2700c56017860f 310 PRINTS PR00146 Dihydrodipicolinate synthase signature 118 134 2.6E-7 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SMALA_RS40380 071d48f75dabf79c1e2700c56017860f 310 SMART SM01130 10 302 4.7E-94 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SMALA_RS40380 071d48f75dabf79c1e2700c56017860f 310 PIRSF PIRSF001365 11 307 1.2E-74 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SMALA_RS40380 071d48f75dabf79c1e2700c56017860f 310 Gene3D G3DSA:3.20.20.70 1 306 1.5E-85 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS38980 6752bf9f1fa16197a68cb40efb6e95c6 828 SMART SM00331 478 696 6.9E-35 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS38980 6752bf9f1fa16197a68cb40efb6e95c6 828 Gene3D G3DSA:3.30.450.40 322 454 2.0E-19 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS38980 6752bf9f1fa16197a68cb40efb6e95c6 828 SUPERFAMILY SSF81606 492 694 9.68E-5 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS38980 6752bf9f1fa16197a68cb40efb6e95c6 828 Gene3D G3DSA:3.30.450.20 37 136 2.4E-7 T 29-03-2018 SMALA_RS38980 6752bf9f1fa16197a68cb40efb6e95c6 828 Pfam PF08448 PAS fold 165 267 2.4E-10 T 29-03-2018 IPR013656 PAS fold-4 SMALA_RS38980 6752bf9f1fa16197a68cb40efb6e95c6 828 Gene3D G3DSA:3.60.40.10 455 699 8.4E-36 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS38980 6752bf9f1fa16197a68cb40efb6e95c6 828 SUPERFAMILY SSF55781 346 460 1.94E-12 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS38980 6752bf9f1fa16197a68cb40efb6e95c6 828 SUPERFAMILY SSF55785 39 121 4.19E-6 T 29-03-2018 IPR000014 PAS domain SMALA_RS38980 6752bf9f1fa16197a68cb40efb6e95c6 828 SUPERFAMILY SSF55874 735 801 5.72E-7 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS38980 6752bf9f1fa16197a68cb40efb6e95c6 828 SUPERFAMILY SSF55785 176 269 1.09E-5 T 29-03-2018 IPR000014 PAS domain SMALA_RS38980 6752bf9f1fa16197a68cb40efb6e95c6 828 SMART SM00065 270 457 0.0077 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS38980 6752bf9f1fa16197a68cb40efb6e95c6 828 Gene3D G3DSA:3.30.450.20 137 276 1.6E-11 T 29-03-2018 SMALA_RS38980 6752bf9f1fa16197a68cb40efb6e95c6 828 Pfam PF13581 Histidine kinase-like ATPase domain 709 817 1.6E-7 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS38980 6752bf9f1fa16197a68cb40efb6e95c6 828 Gene3D G3DSA:3.30.565.10 700 826 2.6E-10 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS38980 6752bf9f1fa16197a68cb40efb6e95c6 828 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 505 696 9.7E-44 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS36985 a93a9c6d3a943c88ce636b596bd63cb4 477 Gene3D G3DSA:1.10.1040.10 295 471 4.6E-48 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMALA_RS36985 a93a9c6d3a943c88ce636b596bd63cb4 477 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 33 193 1.6E-30 T 29-03-2018 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 SMALA_RS36985 a93a9c6d3a943c88ce636b596bd63cb4 477 Gene3D G3DSA:3.40.50.720 7 290 8.8E-97 T 29-03-2018 SMALA_RS36985 a93a9c6d3a943c88ce636b596bd63cb4 477 SUPERFAMILY SSF48179 292 467 3.4E-42 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMALA_RS36985 a93a9c6d3a943c88ce636b596bd63cb4 477 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 226 419 5.4E-56 T 29-03-2018 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 SMALA_RS36985 a93a9c6d3a943c88ce636b596bd63cb4 477 ProSitePatterns PS00974 Mannitol dehydrogenases signature. 227 239 - T 29-03-2018 IPR023027 Mannitol dehydrogenase, conserved site GO:0019594|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 SMALA_RS36985 a93a9c6d3a943c88ce636b596bd63cb4 477 PRINTS PR00084 Mannitol dehydrogenase signature 34 44 1.2E-11 T 29-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 SMALA_RS36985 a93a9c6d3a943c88ce636b596bd63cb4 477 PRINTS PR00084 Mannitol dehydrogenase signature 227 240 1.2E-11 T 29-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 SMALA_RS36985 a93a9c6d3a943c88ce636b596bd63cb4 477 PRINTS PR00084 Mannitol dehydrogenase signature 257 272 1.2E-11 T 29-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 SMALA_RS36985 a93a9c6d3a943c88ce636b596bd63cb4 477 SUPERFAMILY SSF51735 19 290 5.51E-80 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS23605 c376b0c19d298088879ab14053a8fa08 341 Gene3D G3DSA:3.40.50.1980 39 181 9.3E-14 T 29-03-2018 SMALA_RS23605 c376b0c19d298088879ab14053a8fa08 341 Pfam PF01497 Periplasmic binding protein 72 312 4.9E-16 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 SMALA_RS23605 c376b0c19d298088879ab14053a8fa08 341 Gene3D G3DSA:3.40.50.1980 182 341 2.2E-21 T 29-03-2018 SMALA_RS23605 c376b0c19d298088879ab14053a8fa08 341 SUPERFAMILY SSF53807 48 332 1.06E-28 T 29-03-2018 SMALA_RS27060 aeb2d88e8fc1aabcd0070137504b6e4d 187 Gene3D G3DSA:3.10.450.40 124 178 6.0E-11 T 29-03-2018 SMALA_RS27060 aeb2d88e8fc1aabcd0070137504b6e4d 187 Gene3D G3DSA:3.10.450.40 49 103 1.4E-6 T 29-03-2018 SMALA_RS27060 aeb2d88e8fc1aabcd0070137504b6e4d 187 Pfam PF03413 Peptidase propeptide and YPEB domain 126 175 1.9E-5 T 29-03-2018 IPR025711 PepSY domain SMALA_RS01565 3c6b44d50ef74f17956769d7a8c5c53f 557 Pfam PF00005 ABC transporter 29 176 2.2E-21 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS01565 3c6b44d50ef74f17956769d7a8c5c53f 557 Pfam PF00005 ABC transporter 359 489 1.6E-19 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS01565 3c6b44d50ef74f17956769d7a8c5c53f 557 Gene3D G3DSA:3.40.50.300 340 552 1.4E-36 T 29-03-2018 SMALA_RS01565 3c6b44d50ef74f17956769d7a8c5c53f 557 Gene3D G3DSA:3.40.50.300 9 330 1.7E-54 T 29-03-2018 SMALA_RS01565 3c6b44d50ef74f17956769d7a8c5c53f 557 SUPERFAMILY SSF52540 327 525 9.31E-36 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS01565 3c6b44d50ef74f17956769d7a8c5c53f 557 SMART SM00382 35 221 1.3E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS01565 3c6b44d50ef74f17956769d7a8c5c53f 557 SMART SM00382 368 550 1.6E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS01565 3c6b44d50ef74f17956769d7a8c5c53f 557 SUPERFAMILY SSF52540 22 226 5.51E-43 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS04055 ccdd7b93841ac06c6d9774f571f71f59 320 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 259 285 - T 29-03-2018 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 SMALA_RS04055 ccdd7b93841ac06c6d9774f571f71f59 320 Gene3D G3DSA:3.40.50.1220 191 320 1.7E-59 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain SMALA_RS04055 ccdd7b93841ac06c6d9774f571f71f59 320 SUPERFAMILY SSF52467 194 314 5.03E-48 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain SMALA_RS04055 ccdd7b93841ac06c6d9774f571f71f59 320 SUPERFAMILY SSF52402 3 185 7.67E-35 T 29-03-2018 SMALA_RS04055 ccdd7b93841ac06c6d9774f571f71f59 320 Pfam PF01012 Electron transfer flavoprotein domain 4 173 4.8E-27 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 SMALA_RS04055 ccdd7b93841ac06c6d9774f571f71f59 320 SMART SM00893 4 187 3.6E-21 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 SMALA_RS04055 ccdd7b93841ac06c6d9774f571f71f59 320 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 196 278 2.6E-36 T 29-03-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 SMALA_RS04055 ccdd7b93841ac06c6d9774f571f71f59 320 Gene3D G3DSA:3.40.50.620 1 187 3.1E-37 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS04055 ccdd7b93841ac06c6d9774f571f71f59 320 PIRSF PIRSF000089 1 320 9.4E-98 T 29-03-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 SMALA_RS27810 9d581bd52e11c3bbd0ab1d359b98f795 532 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 16 32 - T 29-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 SMALA_RS27810 9d581bd52e11c3bbd0ab1d359b98f795 532 SUPERFAMILY SSF51569 6 297 1.32E-74 T 29-03-2018 SMALA_RS27810 9d581bd52e11c3bbd0ab1d359b98f795 532 TIGRFAM TIGR00977 citramal_synth: citramalate synthase 10 525 1.6E-190 T 29-03-2018 IPR005675 Citramalate synthase GO:0019752|GO:0046912 KEGG: 00290+2.3.1.182|KEGG: 00660+2.3.1.182|MetaCyc: PWY-5101 SMALA_RS27810 9d581bd52e11c3bbd0ab1d359b98f795 532 Gene3D G3DSA:3.20.20.70 2 355 2.1E-98 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS27810 9d581bd52e11c3bbd0ab1d359b98f795 532 SMART SM00917 380 523 3.1E-37 T 29-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 SMALA_RS27810 9d581bd52e11c3bbd0ab1d359b98f795 532 Pfam PF00682 HMGL-like 11 278 1.9E-45 T 29-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 SMALA_RS27810 9d581bd52e11c3bbd0ab1d359b98f795 532 SUPERFAMILY SSF110921 404 518 6.02E-21 T 29-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 SMALA_RS27810 9d581bd52e11c3bbd0ab1d359b98f795 532 Pfam PF08502 LeuA allosteric (dimerisation) domain 380 521 2.9E-25 T 29-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 SMALA_RS05835 1322c0b40eb13a87f2747e1f7c94c676 116 SUPERFAMILY SSF57783 4 38 2.04E-13 T 29-03-2018 SMALA_RS05835 1322c0b40eb13a87f2747e1f7c94c676 116 Gene3D G3DSA:2.30.30.40 46 115 2.0E-33 T 29-03-2018 SMALA_RS05835 1322c0b40eb13a87f2747e1f7c94c676 116 TIGRFAM TIGR00686 phnA: putative alkylphosphonate utilization operon protein PhnA 4 116 2.2E-36 T 29-03-2018 IPR004624 PhnA protein SMALA_RS05835 1322c0b40eb13a87f2747e1f7c94c676 116 Pfam PF03831 PhnA domain 47 116 2.7E-31 T 29-03-2018 IPR013988 PhnA protein, C-terminal SMALA_RS05835 1322c0b40eb13a87f2747e1f7c94c676 116 Pfam PF08274 PhnA Zinc-Ribbon 5 33 2.1E-12 T 29-03-2018 IPR013987 PhnA protein, N-terminal SMALA_RS05835 1322c0b40eb13a87f2747e1f7c94c676 116 SUPERFAMILY SSF82057 44 116 2.66E-24 T 29-03-2018 SMALA_RS05835 1322c0b40eb13a87f2747e1f7c94c676 116 Gene3D G3DSA:2.20.25.10 3 40 4.7E-15 T 29-03-2018 SMALA_RS31580 4eb08d9f82c1305e196186d0888c40f9 355 SUPERFAMILY SSF103481 204 303 1.27E-17 T 29-03-2018 SMALA_RS31580 4eb08d9f82c1305e196186d0888c40f9 355 SUPERFAMILY SSF103481 73 163 1.31E-15 T 29-03-2018 SMALA_RS31580 4eb08d9f82c1305e196186d0888c40f9 355 Pfam PF00892 EamA-like transporter family 171 302 4.1E-22 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SMALA_RS31580 4eb08d9f82c1305e196186d0888c40f9 355 Pfam PF00892 EamA-like transporter family 32 160 6.7E-16 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SMALA_RS36220 6aaab192fa6128297c57ad0bcc8f821f 257 Gene3D G3DSA:3.40.50.2300 17 155 2.2E-35 T 29-03-2018 SMALA_RS36220 6aaab192fa6128297c57ad0bcc8f821f 257 SUPERFAMILY SSF46894 161 255 6.24E-25 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS36220 6aaab192fa6128297c57ad0bcc8f821f 257 SMART SM00448 20 130 5.0E-41 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS36220 6aaab192fa6128297c57ad0bcc8f821f 257 SMART SM00862 184 255 4.3E-20 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS36220 6aaab192fa6128297c57ad0bcc8f821f 257 Gene3D G3DSA:1.10.10.10 156 257 1.4E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS36220 6aaab192fa6128297c57ad0bcc8f821f 257 SUPERFAMILY SSF52172 17 140 3.7E-39 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS36220 6aaab192fa6128297c57ad0bcc8f821f 257 Pfam PF00486 Transcriptional regulatory protein, C terminal 184 255 1.1E-19 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS36220 6aaab192fa6128297c57ad0bcc8f821f 257 Pfam PF00072 Response regulator receiver domain 23 131 6.5E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS06600 2f41a988fc43633fc7d2204730b95b7d 181 SUPERFAMILY SSF48498 68 151 8.9E-5 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS06600 2f41a988fc43633fc7d2204730b95b7d 181 Gene3D G3DSA:1.10.10.60 1 44 1.4E-15 T 29-03-2018 SMALA_RS06600 2f41a988fc43633fc7d2204730b95b7d 181 Pfam PF00440 Bacterial regulatory proteins, tetR family 1 47 1.3E-16 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS06600 2f41a988fc43633fc7d2204730b95b7d 181 SUPERFAMILY SSF46689 1 72 3.44E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS06600 2f41a988fc43633fc7d2204730b95b7d 181 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 1 14 3.1E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS06600 2f41a988fc43633fc7d2204730b95b7d 181 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 45 3.1E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS06600 2f41a988fc43633fc7d2204730b95b7d 181 Gene3D G3DSA:1.10.357.10 45 178 5.5E-17 T 29-03-2018 SMALA_RS08930 3c87a24c143a2c39fbd848328db4e807 256 Gene3D G3DSA:3.40.50.720 3 255 7.6E-40 T 29-03-2018 SMALA_RS08930 3c87a24c143a2c39fbd848328db4e807 256 PIRSF PIRSF000094 2 256 2.6E-81 T 29-03-2018 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 SMALA_RS08930 3c87a24c143a2c39fbd848328db4e807 256 SUPERFAMILY SSF51735 7 254 3.46E-51 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS08930 3c87a24c143a2c39fbd848328db4e807 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 252 2.6E-65 T 29-03-2018 SMALA_RS11515 ea2eabea57fd48db5c4cbd159a942988 699 Pfam PF09594 Glycosyltransferase family 87 55 290 3.1E-31 T 29-03-2018 IPR018584 Glycosyltransferase family 87 GO:0016758 SMALA_RS11515 ea2eabea57fd48db5c4cbd159a942988 699 Pfam PF14378 PAP2 superfamily 437 617 1.9E-48 T 29-03-2018 IPR026841 Inositolphosphotransferase Aur1/Ipt1 SMALA_RS17555 19b39e7330a4e081050fd30f75c5925d 320 Gene3D G3DSA:3.40.1190.20 43 317 1.6E-44 T 29-03-2018 IPR029056 Ribokinase-like SMALA_RS17555 19b39e7330a4e081050fd30f75c5925d 320 SUPERFAMILY SSF53613 2 293 5.61E-59 T 29-03-2018 IPR029056 Ribokinase-like SMALA_RS17555 19b39e7330a4e081050fd30f75c5925d 320 Pfam PF00294 pfkB family carbohydrate kinase 12 294 1.5E-37 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB SMALA_RS17555 19b39e7330a4e081050fd30f75c5925d 320 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 254 267 - T 29-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 SMALA_RS17555 19b39e7330a4e081050fd30f75c5925d 320 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 2 313 5.2E-89 T 29-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 SMALA_RS17555 19b39e7330a4e081050fd30f75c5925d 320 Gene3D G3DSA:2.20.150.10 10 42 2.3E-16 T 29-03-2018 IPR023314 Tagatose-6-phosphate kinase/1-phosphofructokinase N-terminal domain SMALA_RS17555 19b39e7330a4e081050fd30f75c5925d 320 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 36 60 - T 29-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 SMALA_RS17555 19b39e7330a4e081050fd30f75c5925d 320 PIRSF PIRSF000535 1 316 1.7E-77 T 29-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 SMALA_RS05380 3dbe2d99ae99c6738fc010ee22bda9c7 356 Gene3D G3DSA:3.40.50.720 32 141 1.9E-25 T 29-03-2018 SMALA_RS05380 3dbe2d99ae99c6738fc010ee22bda9c7 356 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 136 315 1.5E-51 T 29-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 SMALA_RS05380 3dbe2d99ae99c6738fc010ee22bda9c7 356 SUPERFAMILY SSF51735 128 316 4.94E-51 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS05380 3dbe2d99ae99c6738fc010ee22bda9c7 356 SUPERFAMILY SSF52283 62 163 6.8E-23 T 29-03-2018 SMALA_RS05380 3dbe2d99ae99c6738fc010ee22bda9c7 356 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 61 347 4.0E-18 T 29-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 SMALA_RS05380 3dbe2d99ae99c6738fc010ee22bda9c7 356 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 254 270 - T 29-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site SMALA_RS05380 3dbe2d99ae99c6738fc010ee22bda9c7 356 Gene3D G3DSA:3.40.50.720 142 318 1.3E-49 T 29-03-2018 SMALA_RS11210 cd2644333720cefaaee38fe5ea4fef49 400 SMART SM00331 175 395 3.2E-15 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS11210 cd2644333720cefaaee38fe5ea4fef49 400 Gene3D G3DSA:3.60.40.10 140 397 9.8E-28 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS11210 cd2644333720cefaaee38fe5ea4fef49 400 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 202 395 4.3E-39 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS11210 cd2644333720cefaaee38fe5ea4fef49 400 SUPERFAMILY SSF81606 189 395 4.71E-11 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS29365 686975861380cbb7fe7347885d039d39 309 Gene3D G3DSA:1.10.620.20 56 250 3.5E-4 T 29-03-2018 SMALA_RS29365 686975861380cbb7fe7347885d039d39 309 Pfam PF11583 P-aminobenzoate N-oxygenase AurF 10 298 1.5E-60 T 29-03-2018 IPR025859 P-aminobenzoate N-oxygenase AurF SMALA_RS36295 0fe9975d5212ced47eb08fb668d5ab0e 363 Pfam PF09362 Domain of unknown function (DUF1996) 106 321 8.1E-45 T 29-03-2018 IPR018535 Domain of unknown function DUF1996 SMALA_RS29910 c352669f60cfd989c37a8a7aba1d85bb 503 Pfam PF05114 Protein of unknown function (DUF692) 6 270 1.5E-82 T 29-03-2018 IPR007801 Uncharacterised protein family UPF0276 SMALA_RS29910 c352669f60cfd989c37a8a7aba1d85bb 503 Gene3D G3DSA:3.20.20.150 1 284 8.7E-77 T 29-03-2018 SMALA_RS29910 c352669f60cfd989c37a8a7aba1d85bb 503 SUPERFAMILY SSF51658 22 225 2.49E-12 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SMALA_RS25635 03d8013507d125b9c1322314b928ba21 307 Gene3D G3DSA:1.10.3720.10 2 294 1.2E-43 T 29-03-2018 SMALA_RS25635 03d8013507d125b9c1322314b928ba21 307 SUPERFAMILY SSF161098 90 288 6.8E-19 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS25635 03d8013507d125b9c1322314b928ba21 307 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 306 5.6E-37 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS10495 da6ab422f4cd5ff6fde685af12ae2fff 81 Gene3D G3DSA:2.30.30.380 3 45 0.037 T 29-03-2018 SMALA_RS05055 facaf77156ec71b20ab9c8bf8a785791 473 Gene3D G3DSA:3.30.565.10 309 473 1.7E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS05055 facaf77156ec71b20ab9c8bf8a785791 473 SMART SM00387 360 473 1.9E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS05055 facaf77156ec71b20ab9c8bf8a785791 473 SMART SM00388 241 308 1.0E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS05055 facaf77156ec71b20ab9c8bf8a785791 473 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 360 471 8.4E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS05055 facaf77156ec71b20ab9c8bf8a785791 473 SUPERFAMILY SSF47384 217 306 2.35E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS05055 facaf77156ec71b20ab9c8bf8a785791 473 SUPERFAMILY SSF158472 182 230 3.66E-8 T 29-03-2018 SMALA_RS05055 facaf77156ec71b20ab9c8bf8a785791 473 Pfam PF00512 His Kinase A (phospho-acceptor) domain 242 307 4.5E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS05055 facaf77156ec71b20ab9c8bf8a785791 473 SUPERFAMILY SSF55874 298 470 4.58E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS05055 facaf77156ec71b20ab9c8bf8a785791 473 SMART SM00304 179 233 1.5E-14 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMALA_RS05055 facaf77156ec71b20ab9c8bf8a785791 473 Pfam PF00672 HAMP domain 181 229 2.4E-13 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMALA_RS05055 facaf77156ec71b20ab9c8bf8a785791 473 PRINTS PR00344 Bacterial sensor protein C-terminal signature 433 451 1.4E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS05055 facaf77156ec71b20ab9c8bf8a785791 473 PRINTS PR00344 Bacterial sensor protein C-terminal signature 415 425 1.4E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS05055 facaf77156ec71b20ab9c8bf8a785791 473 PRINTS PR00344 Bacterial sensor protein C-terminal signature 457 470 1.4E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS05055 facaf77156ec71b20ab9c8bf8a785791 473 PRINTS PR00344 Bacterial sensor protein C-terminal signature 397 411 1.4E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS05055 facaf77156ec71b20ab9c8bf8a785791 473 Gene3D G3DSA:1.10.287.130 224 304 1.4E-16 T 29-03-2018 SMALA_RS19490 3b4f9f075f8616b71abb687919a23c66 298 Gene3D G3DSA:3.40.190.10 87 172 1.1E-9 T 29-03-2018 SMALA_RS19490 3b4f9f075f8616b71abb687919a23c66 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 4.8E-22 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS19490 3b4f9f075f8616b71abb687919a23c66 298 SUPERFAMILY SSF53850 90 295 1.71E-23 T 29-03-2018 SMALA_RS19490 3b4f9f075f8616b71abb687919a23c66 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 5.3E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS19490 3b4f9f075f8616b71abb687919a23c66 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 5.3E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS19490 3b4f9f075f8616b71abb687919a23c66 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 5.3E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS19490 3b4f9f075f8616b71abb687919a23c66 298 SUPERFAMILY SSF46785 1 76 9.13E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS19490 3b4f9f075f8616b71abb687919a23c66 298 Gene3D G3DSA:1.10.10.10 1 82 1.9E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS19490 3b4f9f075f8616b71abb687919a23c66 298 Gene3D G3DSA:3.40.190.10 173 263 9.5E-19 T 29-03-2018 SMALA_RS19490 3b4f9f075f8616b71abb687919a23c66 298 Pfam PF03466 LysR substrate binding domain 90 294 3.2E-23 T 29-03-2018 IPR005119 LysR, substrate-binding SMALA_RS31305 69ce5fea10033940175019181ebbe248 290 SMART SM00926 230 284 3.1E-18 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS31305 69ce5fea10033940175019181ebbe248 290 Pfam PF00037 4Fe-4S binding domain 194 211 3.8E-7 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain SMALA_RS31305 69ce5fea10033940175019181ebbe248 290 SUPERFAMILY SSF54862 86 218 1.53E-24 T 29-03-2018 SMALA_RS31305 69ce5fea10033940175019181ebbe248 290 SUPERFAMILY SSF54292 13 127 3.6E-31 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SMALA_RS31305 69ce5fea10033940175019181ebbe248 290 SUPERFAMILY SSF53706 194 284 1.73E-17 T 29-03-2018 SMALA_RS31305 69ce5fea10033940175019181ebbe248 290 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 235 253 - T 29-03-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 KEGG: 00910+1.7.99.4 SMALA_RS31305 69ce5fea10033940175019181ebbe248 290 Pfam PF12837 4Fe-4S binding domain 147 165 1.7E-5 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain SMALA_RS31305 69ce5fea10033940175019181ebbe248 290 Gene3D G3DSA:3.10.20.30 10 99 1.4E-9 T 29-03-2018 IPR012675 Beta-grasp domain SMALA_RS31305 69ce5fea10033940175019181ebbe248 290 Gene3D G3DSA:3.30.70.20 117 229 1.5E-16 T 29-03-2018 SMALA_RS31305 69ce5fea10033940175019181ebbe248 290 Gene3D G3DSA:2.20.25.90 230 285 6.0E-19 T 29-03-2018 SMALA_RS31305 69ce5fea10033940175019181ebbe248 290 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 196 207 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site SMALA_RS31305 69ce5fea10033940175019181ebbe248 290 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 11 87 5.0E-22 T 29-03-2018 SMALA_RS31305 69ce5fea10033940175019181ebbe248 290 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 232 284 1.6E-19 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS02695 fd99ac1770d483b2cad353f1a98580eb 219 SUPERFAMILY SSF101874 43 214 5.49E-54 T 29-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like SMALA_RS02695 fd99ac1770d483b2cad353f1a98580eb 219 SMART SM00867 44 213 5.9E-64 T 29-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like SMALA_RS02695 fd99ac1770d483b2cad353f1a98580eb 219 Gene3D G3DSA:2.40.128.110 40 218 8.5E-51 T 29-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like SMALA_RS02695 fd99ac1770d483b2cad353f1a98580eb 219 Pfam PF04264 YceI-like domain 45 211 3.0E-43 T 29-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like SMALA_RS00575 2639ec0afeb395e5daafcd0a4889926f 246 Pfam PF17124 ThiJ/PfpI family-like 7 202 4.1E-38 T 29-03-2018 IPR032633 ThiJ/PfpI family-like SMALA_RS00575 2639ec0afeb395e5daafcd0a4889926f 246 SUPERFAMILY SSF52317 2 245 2.07E-37 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS00575 2639ec0afeb395e5daafcd0a4889926f 246 Gene3D G3DSA:3.40.50.880 7 246 7.8E-41 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS39225 8e155a79bba625b70526641b6a340060 403 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 340 349 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMALA_RS39225 8e155a79bba625b70526641b6a340060 403 Gene3D G3DSA:1.10.630.10 5 403 2.8E-72 T 29-03-2018 SMALA_RS39225 8e155a79bba625b70526641b6a340060 403 Pfam PF00067 Cytochrome P450 268 368 1.3E-20 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS39225 8e155a79bba625b70526641b6a340060 403 PRINTS PR00359 B-class P450 signature 289 316 5.8E-54 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS39225 8e155a79bba625b70526641b6a340060 403 PRINTS PR00359 B-class P450 signature 338 347 5.8E-54 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS39225 8e155a79bba625b70526641b6a340060 403 PRINTS PR00359 B-class P450 signature 142 158 5.8E-54 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS39225 8e155a79bba625b70526641b6a340060 403 PRINTS PR00359 B-class P450 signature 347 358 5.8E-54 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS39225 8e155a79bba625b70526641b6a340060 403 PRINTS PR00359 B-class P450 signature 159 174 5.8E-54 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS39225 8e155a79bba625b70526641b6a340060 403 PRINTS PR00359 B-class P450 signature 317 332 5.8E-54 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS39225 8e155a79bba625b70526641b6a340060 403 PRINTS PR00359 B-class P450 signature 95 106 5.8E-54 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS39225 8e155a79bba625b70526641b6a340060 403 PRINTS PR00359 B-class P450 signature 272 283 5.8E-54 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS39225 8e155a79bba625b70526641b6a340060 403 PRINTS PR00359 B-class P450 signature 196 218 5.8E-54 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS39225 8e155a79bba625b70526641b6a340060 403 PRINTS PR00385 P450 superfamily signature 237 254 7.3E-7 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS39225 8e155a79bba625b70526641b6a340060 403 PRINTS PR00385 P450 superfamily signature 347 358 7.3E-7 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS39225 8e155a79bba625b70526641b6a340060 403 PRINTS PR00385 P450 superfamily signature 272 283 7.3E-7 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS39225 8e155a79bba625b70526641b6a340060 403 PRINTS PR00385 P450 superfamily signature 338 347 7.3E-7 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS39225 8e155a79bba625b70526641b6a340060 403 SUPERFAMILY SSF48264 18 401 7.47E-92 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS01130 630f8b792628c66bca169c261c43cae3 287 SUPERFAMILY SSF51197 6 259 1.05E-85 T 29-03-2018 SMALA_RS01130 630f8b792628c66bca169c261c43cae3 287 Gene3D G3DSA:3.60.130.10 2 269 1.8E-73 T 29-03-2018 SMALA_RS01130 630f8b792628c66bca169c261c43cae3 287 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 8 250 1.1E-58 T 29-03-2018 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 SMALA_RS04410 74493f32b9c156139d64e0dd03576e93 64 Gene3D G3DSA:3.30.70.20 1 64 1.5E-5 T 29-03-2018 SMALA_RS04410 74493f32b9c156139d64e0dd03576e93 64 SUPERFAMILY SSF54862 2 62 6.58E-12 T 29-03-2018 SMALA_RS04410 74493f32b9c156139d64e0dd03576e93 64 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 5 62 3.9E-12 T 29-03-2018 SMALA_RS04410 74493f32b9c156139d64e0dd03576e93 64 PRINTS PR00352 3Fe-4S ferredoxin signature 48 60 3.3E-6 T 29-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 SMALA_RS04410 74493f32b9c156139d64e0dd03576e93 64 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 3.3E-6 T 29-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 SMALA_RS04410 74493f32b9c156139d64e0dd03576e93 64 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 3.3E-6 T 29-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 SMALA_RS28030 fc76049934f0efe51ce82a31cefda666 158 Gene3D G3DSA:1.10.10.10 33 134 2.5E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS28030 fc76049934f0efe51ce82a31cefda666 158 SUPERFAMILY SSF46785 21 133 2.64E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS28030 fc76049934f0efe51ce82a31cefda666 158 Pfam PF01638 HxlR-like helix-turn-helix 36 121 1.9E-24 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type SMALA_RS05445 3245ed2a509fde6942cf5fa693d5bb83 197 Pfam PF07336 Putative stress-induced transcription regulator 19 150 8.3E-25 T 29-03-2018 IPR010852 Putative stress-induced transcription regulator SMALA_RS05445 3245ed2a509fde6942cf5fa693d5bb83 197 SUPERFAMILY SSF160904 16 192 2.09E-42 T 29-03-2018 SMALA_RS05445 3245ed2a509fde6942cf5fa693d5bb83 197 Pfam PF11706 CGNR zinc finger 154 193 1.1E-7 T 29-03-2018 IPR021005 Zinc finger, CGNR SMALA_RS05445 3245ed2a509fde6942cf5fa693d5bb83 197 Gene3D G3DSA:1.10.3300.10 13 195 4.3E-38 T 29-03-2018 IPR023286 ABATE domain SMALA_RS12650 757f93a059ca81f201d9942352d966de 745 Pfam PF00656 Caspase domain 12 257 2.2E-16 T 29-03-2018 SMALA_RS12650 757f93a059ca81f201d9942352d966de 745 Gene3D G3DSA:3.40.50.1460 3 258 8.2E-31 T 29-03-2018 SMALA_RS12650 757f93a059ca81f201d9942352d966de 745 SUPERFAMILY SSF52129 78 257 2.41E-6 T 29-03-2018 IPR029030 Caspase-like domain SMALA_RS14535 ee3af65cc3cbc61f5d4d551abd1377ec 798 TIGRFAM TIGR00702 TIGR00702: YcaO-type kinase domain 433 667 2.1E-22 T 29-03-2018 IPR003776 YcaO-like domain SMALA_RS14535 ee3af65cc3cbc61f5d4d551abd1377ec 798 TIGRFAM TIGR03604 TOMM_cyclo_SagD: thiazole/oxazole-forming peptide maturase, SagD family component 437 796 3.6E-70 T 29-03-2018 IPR027624 Thiazole/oxazole-forming peptide maturase, SagD family component SMALA_RS14535 ee3af65cc3cbc61f5d4d551abd1377ec 798 TIGRFAM TIGR03882 cyclo_dehyd_2: bacteriocin biosynthesis cyclodehydratase domain 221 392 5.6E-37 T 29-03-2018 IPR022291 Bacteriocin biosynthesis, cyclodehydratase domain SMALA_RS14535 ee3af65cc3cbc61f5d4d551abd1377ec 798 Pfam PF02624 YcaO cyclodehydratase, ATP-ad Mg2+-binding 437 761 6.3E-88 T 29-03-2018 IPR003776 YcaO-like domain SMALA_RS14535 ee3af65cc3cbc61f5d4d551abd1377ec 798 Gene3D G3DSA:3.40.50.720 189 351 9.0E-14 T 29-03-2018 SMALA_RS39795 f8e68c6c7c7abaa83483f657a6860ff7 538 Gene3D G3DSA:3.30.420.40 57 280 4.5E-53 T 29-03-2018 SMALA_RS39795 f8e68c6c7c7abaa83483f657a6860ff7 538 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 289 475 8.0E-37 T 29-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 SMALA_RS39795 f8e68c6c7c7abaa83483f657a6860ff7 538 SUPERFAMILY SSF53067 284 523 1.29E-53 T 29-03-2018 SMALA_RS39795 f8e68c6c7c7abaa83483f657a6860ff7 538 PIRSF PIRSF000538 60 530 5.2E-88 T 29-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 SMALA_RS39795 f8e68c6c7c7abaa83483f657a6860ff7 538 SUPERFAMILY SSF53067 64 280 5.44E-47 T 29-03-2018 SMALA_RS39795 f8e68c6c7c7abaa83483f657a6860ff7 538 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 65 278 9.9E-26 T 29-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 SMALA_RS39795 f8e68c6c7c7abaa83483f657a6860ff7 538 Gene3D G3DSA:3.30.420.40 281 531 3.6E-57 T 29-03-2018 SMALA_RS39795 f8e68c6c7c7abaa83483f657a6860ff7 538 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 389 409 - T 29-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 SMALA_RS32435 cf534f84938e6bbf81d62296887becc3 384 Pfam PF01960 ArgJ family 11 384 5.6E-127 T 29-03-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 SMALA_RS32435 cf534f84938e6bbf81d62296887becc3 384 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 17 382 4.0E-179 T 29-03-2018 SMALA_RS32435 cf534f84938e6bbf81d62296887becc3 384 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 2 383 3.1E-104 T 29-03-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 SMALA_RS32435 cf534f84938e6bbf81d62296887becc3 384 Gene3D G3DSA:3.60.70.12 1 260 4.8E-94 T 29-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 SMALA_RS32435 cf534f84938e6bbf81d62296887becc3 384 SUPERFAMILY SSF56266 7 380 1.29E-125 T 29-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 SMALA_RS32435 cf534f84938e6bbf81d62296887becc3 384 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 384 131.846 T 29-03-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 SMALA_RS38105 4ce011ade5e6701b62374439dc74fca1 302 Pfam PF00175 Oxidoreductase NAD-binding domain 107 195 1.3E-5 T 29-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 SMALA_RS38105 4ce011ade5e6701b62374439dc74fca1 302 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 229 293 1.1E-11 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SMALA_RS38105 4ce011ade5e6701b62374439dc74fca1 302 Gene3D G3DSA:3.40.50.80 97 208 1.9E-18 T 29-03-2018 SMALA_RS38105 4ce011ade5e6701b62374439dc74fca1 302 PRINTS PR00409 Phthalate dioxygenase reductase family signature 35 47 5.9E-27 T 29-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 SMALA_RS38105 4ce011ade5e6701b62374439dc74fca1 302 PRINTS PR00409 Phthalate dioxygenase reductase family signature 182 190 5.9E-27 T 29-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 SMALA_RS38105 4ce011ade5e6701b62374439dc74fca1 302 PRINTS PR00409 Phthalate dioxygenase reductase family signature 47 61 5.9E-27 T 29-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 SMALA_RS38105 4ce011ade5e6701b62374439dc74fca1 302 PRINTS PR00409 Phthalate dioxygenase reductase family signature 106 125 5.9E-27 T 29-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 SMALA_RS38105 4ce011ade5e6701b62374439dc74fca1 302 PRINTS PR00409 Phthalate dioxygenase reductase family signature 25 35 5.9E-27 T 29-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 SMALA_RS38105 4ce011ade5e6701b62374439dc74fca1 302 PRINTS PR00409 Phthalate dioxygenase reductase family signature 71 85 5.9E-27 T 29-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 SMALA_RS38105 4ce011ade5e6701b62374439dc74fca1 302 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 256 264 - T 29-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 SMALA_RS38105 4ce011ade5e6701b62374439dc74fca1 302 Gene3D G3DSA:3.10.20.30 209 302 1.9E-17 T 29-03-2018 IPR012675 Beta-grasp domain SMALA_RS38105 4ce011ade5e6701b62374439dc74fca1 302 SUPERFAMILY SSF63380 3 95 6.43E-23 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 SMALA_RS38105 4ce011ade5e6701b62374439dc74fca1 302 Gene3D G3DSA:2.40.30.10 1 96 3.2E-14 T 29-03-2018 SMALA_RS38105 4ce011ade5e6701b62374439dc74fca1 302 SUPERFAMILY SSF54292 199 301 3.67E-25 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SMALA_RS38105 4ce011ade5e6701b62374439dc74fca1 302 SUPERFAMILY SSF52343 93 213 5.11E-25 T 29-03-2018 SMALA_RS00320 7fce53b4bbe4f1c3814f6e7d0294cd11 246 Gene3D G3DSA:1.10.1660.10 57 138 1.7E-6 T 29-03-2018 SMALA_RS00320 7fce53b4bbe4f1c3814f6e7d0294cd11 246 Gene3D G3DSA:1.10.1660.10 1 56 4.9E-21 T 29-03-2018 SMALA_RS00320 7fce53b4bbe4f1c3814f6e7d0294cd11 246 SUPERFAMILY SSF46955 1 104 5.49E-25 T 29-03-2018 IPR009061 Putative DNA-binding domain SMALA_RS00320 7fce53b4bbe4f1c3814f6e7d0294cd11 246 SMART SM00422 1 70 3.5E-23 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS00320 7fce53b4bbe4f1c3814f6e7d0294cd11 246 Pfam PF00376 MerR family regulatory protein 2 39 4.1E-17 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS22675 d803973a798cd61cf5c1140483d6fcc9 208 SUPERFAMILY SSF55174 3 208 1.44E-65 T 29-03-2018 SMALA_RS22675 d803973a798cd61cf5c1140483d6fcc9 208 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 208 7.2E-70 T 29-03-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 SMALA_RS22675 d803973a798cd61cf5c1140483d6fcc9 208 Gene3D G3DSA:1.10.1050.10 146 208 7.1E-13 T 29-03-2018 SMALA_RS22675 d803973a798cd61cf5c1140483d6fcc9 208 ProSitePatterns PS00632 Ribosomal protein S4 signature. 96 120 - T 29-03-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMALA_RS22675 d803973a798cd61cf5c1140483d6fcc9 208 Gene3D G3DSA:1.10.1050.10 1 103 5.6E-40 T 29-03-2018 SMALA_RS22675 d803973a798cd61cf5c1140483d6fcc9 208 Pfam PF01479 S4 domain 99 145 1.3E-17 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SMALA_RS22675 d803973a798cd61cf5c1140483d6fcc9 208 SMART SM00363 98 160 2.9E-16 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SMALA_RS22675 d803973a798cd61cf5c1140483d6fcc9 208 SMART SM01390 3 97 8.6E-47 T 29-03-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 SMALA_RS22675 d803973a798cd61cf5c1140483d6fcc9 208 Gene3D G3DSA:3.10.290.10 104 145 2.4E-16 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SMALA_RS22675 d803973a798cd61cf5c1140483d6fcc9 208 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 208 33.357 T 29-03-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 SMALA_RS22675 d803973a798cd61cf5c1140483d6fcc9 208 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 97 2.1E-30 T 29-03-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 SMALA_RS37270 30feea3634c52e77f1602411d8249a37 335 Gene3D G3DSA:1.25.40.120 93 315 6.2E-4 T 29-03-2018 SMALA_RS06340 f218ef86c047eb2a87169567a308e66e 208 SUPERFAMILY SSF53335 3 166 2.56E-30 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS06340 f218ef86c047eb2a87169567a308e66e 208 Gene3D G3DSA:3.40.50.150 3 188 1.1E-25 T 29-03-2018 SMALA_RS06340 f218ef86c047eb2a87169567a308e66e 208 Pfam PF13649 Methyltransferase domain 42 135 5.3E-15 T 29-03-2018 SMALA_RS12065 10f95bdf9fb96c191c758c38ab41ebdc 201 Gene3D G3DSA:1.10.357.10 64 195 1.5E-15 T 29-03-2018 SMALA_RS12065 10f95bdf9fb96c191c758c38ab41ebdc 201 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 96 189 8.8E-7 T 29-03-2018 SMALA_RS12065 10f95bdf9fb96c191c758c38ab41ebdc 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 65 4.8E-13 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS12065 10f95bdf9fb96c191c758c38ab41ebdc 201 Gene3D G3DSA:1.10.10.60 1 63 5.9E-18 T 29-03-2018 SMALA_RS12065 10f95bdf9fb96c191c758c38ab41ebdc 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 1.0E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS12065 10f95bdf9fb96c191c758c38ab41ebdc 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 1.0E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS12065 10f95bdf9fb96c191c758c38ab41ebdc 201 SUPERFAMILY SSF48498 89 192 7.19E-13 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS12065 10f95bdf9fb96c191c758c38ab41ebdc 201 SUPERFAMILY SSF46689 8 72 3.13E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS33950 e88d8a8e648930a8289f2d5746087c7d 497 SUPERFAMILY SSF53474 6 481 2.81E-104 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS33950 e88d8a8e648930a8289f2d5746087c7d 497 Gene3D G3DSA:3.40.50.1820 4 497 3.4E-116 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS33950 e88d8a8e648930a8289f2d5746087c7d 497 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 180 195 - T 29-03-2018 IPR019826 Carboxylesterase type B, active site SMALA_RS33950 e88d8a8e648930a8289f2d5746087c7d 497 Pfam PF00135 Carboxylesterase family 6 484 5.3E-93 T 29-03-2018 IPR002018 Carboxylesterase, type B SMALA_RS34510 14caf82f8ca0186f475c8a27a6752b11 101 Gene3D G3DSA:3.40.630.30 1 99 3.9E-23 T 29-03-2018 SMALA_RS34510 14caf82f8ca0186f475c8a27a6752b11 101 SUPERFAMILY SSF55729 4 92 2.06E-26 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS34510 14caf82f8ca0186f475c8a27a6752b11 101 Pfam PF14542 GCN5-related N-acetyl-transferase 13 90 2.0E-25 T 29-03-2018 IPR031165 Yjdj-type Gcn5-related N-acetyltransferase SMALA_RS14655 c540e3b45688e6bb0920af521950ce44 584 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 539 556 - T 29-03-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SMALA_RS14655 c540e3b45688e6bb0920af521950ce44 584 Gene3D G3DSA:2.40.50.100 515 584 4.9E-19 T 29-03-2018 SMALA_RS14655 c540e3b45688e6bb0920af521950ce44 584 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 114 319 5.2E-75 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SMALA_RS14655 c540e3b45688e6bb0920af521950ce44 584 SMART SM00878 333 441 3.4E-57 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SMALA_RS14655 c540e3b45688e6bb0920af521950ce44 584 SUPERFAMILY SSF51230 511 582 5.37E-20 T 29-03-2018 IPR011053 Single hybrid motif SMALA_RS14655 c540e3b45688e6bb0920af521950ce44 584 Pfam PF00364 Biotin-requiring enzyme 517 582 2.5E-17 T 29-03-2018 IPR000089 Biotin/lipoyl attachment SMALA_RS14655 c540e3b45688e6bb0920af521950ce44 584 SUPERFAMILY SSF52440 2 112 6.91E-46 T 29-03-2018 IPR016185 Pre-ATP-grasp domain SMALA_RS14655 c540e3b45688e6bb0920af521950ce44 584 SUPERFAMILY SSF51246 328 444 4.55E-37 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 SMALA_RS14655 c540e3b45688e6bb0920af521950ce44 584 SUPERFAMILY SSF56059 114 321 2.12E-59 T 29-03-2018 SMALA_RS14655 c540e3b45688e6bb0920af521950ce44 584 Gene3D G3DSA:3.30.470.20 209 444 3.3E-93 T 29-03-2018 SMALA_RS14655 c540e3b45688e6bb0920af521950ce44 584 Gene3D G3DSA:3.30.1490.20 123 208 2.9E-17 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SMALA_RS14655 c540e3b45688e6bb0920af521950ce44 584 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 109 1.6E-43 T 29-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SMALA_RS14655 c540e3b45688e6bb0920af521950ce44 584 Pfam PF02785 Biotin carboxylase C-terminal domain 333 441 1.4E-36 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SMALA_RS14655 c540e3b45688e6bb0920af521950ce44 584 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 285 292 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SMALA_RS14655 c540e3b45688e6bb0920af521950ce44 584 Gene3D G3DSA:3.40.50.20 1 122 1.5E-49 T 29-03-2018 SMALA_RS17585 a49e98a47eb79b3746f54a65c01198af 194 Pfam PF05685 Putative restriction endonuclease 24 190 3.8E-25 T 29-03-2018 IPR008538 Domain of unknown function DUF820 SMALA_RS17585 a49e98a47eb79b3746f54a65c01198af 194 SUPERFAMILY SSF52980 32 192 8.58E-17 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 SMALA_RS17585 a49e98a47eb79b3746f54a65c01198af 194 Gene3D G3DSA:3.90.1570.10 15 194 3.7E-30 T 29-03-2018 SMALA_RS37255 82e3c17fdb7b7e82eaba0079c39fff45 203 SUPERFAMILY SSF47090 129 199 4.19E-13 T 29-03-2018 IPR002477 Peptidoglycan binding-like SMALA_RS37255 82e3c17fdb7b7e82eaba0079c39fff45 203 Pfam PF01471 Putative peptidoglycan binding domain 139 197 1.0E-8 T 29-03-2018 IPR002477 Peptidoglycan binding-like SMALA_RS37255 82e3c17fdb7b7e82eaba0079c39fff45 203 Gene3D G3DSA:1.10.101.10 128 203 4.9E-15 T 29-03-2018 IPR002477 Peptidoglycan binding-like SMALA_RS41450 dbffd02ebf1c904c9a2c8b96a3de07e5 277 Gene3D G3DSA:3.40.50.10320 2 277 2.3E-63 T 29-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 SMALA_RS41450 dbffd02ebf1c904c9a2c8b96a3de07e5 277 Pfam PF02585 GlcNAc-PI de-N-acetylase 9 156 3.6E-27 T 29-03-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 SMALA_RS41450 dbffd02ebf1c904c9a2c8b96a3de07e5 277 SUPERFAMILY SSF102588 5 276 2.75E-61 T 29-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 SMALA_RS27270 7ebcda1a24b6b8ef7456ed83022c2786 458 Gene3D G3DSA:3.40.190.10 19 204 1.2E-33 T 29-03-2018 SMALA_RS27270 7ebcda1a24b6b8ef7456ed83022c2786 458 Gene3D G3DSA:3.40.190.10 228 406 1.7E-12 T 29-03-2018 SMALA_RS27270 7ebcda1a24b6b8ef7456ed83022c2786 458 Pfam PF01547 Bacterial extracellular solute-binding protein 54 362 4.1E-33 T 29-03-2018 IPR006059 Solute-binding family 1 GO:0006810 SMALA_RS27270 7ebcda1a24b6b8ef7456ed83022c2786 458 SUPERFAMILY SSF53850 20 446 9.45E-81 T 29-03-2018 SMALA_RS40465 57fc6ff4b5895218fabc48201f6d64b2 317 Pfam PF03466 LysR substrate binding domain 87 292 3.7E-28 T 29-03-2018 IPR005119 LysR, substrate-binding SMALA_RS40465 57fc6ff4b5895218fabc48201f6d64b2 317 Gene3D G3DSA:1.10.10.10 1 79 3.0E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS40465 57fc6ff4b5895218fabc48201f6d64b2 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.5E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS40465 57fc6ff4b5895218fabc48201f6d64b2 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.5E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS40465 57fc6ff4b5895218fabc48201f6d64b2 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.5E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS40465 57fc6ff4b5895218fabc48201f6d64b2 317 SUPERFAMILY SSF46785 3 104 1.47E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS40465 57fc6ff4b5895218fabc48201f6d64b2 317 SUPERFAMILY SSF53850 88 291 9.95E-29 T 29-03-2018 SMALA_RS40465 57fc6ff4b5895218fabc48201f6d64b2 317 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 5.4E-19 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS40465 57fc6ff4b5895218fabc48201f6d64b2 317 Gene3D G3DSA:3.40.190.10 80 187 1.7E-17 T 29-03-2018 SMALA_RS40465 57fc6ff4b5895218fabc48201f6d64b2 317 Gene3D G3DSA:3.40.190.10 188 267 4.4E-12 T 29-03-2018 SMALA_RS02760 1b5cb4667da07dc2305a8cb630aabc81 371 SUPERFAMILY SSF51679 2 327 1.05E-67 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS02760 1b5cb4667da07dc2305a8cb630aabc81 371 Gene3D G3DSA:3.20.20.30 1 336 3.2E-65 T 29-03-2018 SMALA_RS02760 1b5cb4667da07dc2305a8cb630aabc81 371 Pfam PF00296 Luciferase-like monooxygenase 3 296 3.3E-58 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS02760 1b5cb4667da07dc2305a8cb630aabc81 371 TIGRFAM TIGR04036 LLM_CE1758_fam: putative luciferase-like monooxygenase, FMN-dependent, CE1758 family 1 353 6.0E-214 T 29-03-2018 IPR023934 Luciferase-like monooxygenase, FMN-dependent, putative SMALA_RS13840 64bc5ca994e2854f93ae9d923dde84fc 704 Pfam PF13515 Fusaric acid resistance protein-like 385 506 6.3E-16 T 29-03-2018 SMALA_RS13840 64bc5ca994e2854f93ae9d923dde84fc 704 Pfam PF12805 FUSC-like inner membrane protein yccS 79 191 1.0E-7 T 29-03-2018 IPR032692 Integral membrane protein YccS, N-terminal SMALA_RS13840 64bc5ca994e2854f93ae9d923dde84fc 704 Gene3D G3DSA:3.40.50.150 319 694 9.9E-4 T 29-03-2018 SMALA_RS34890 355d12da5e55f595c94522b6a0370208 408 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 361 380 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 SMALA_RS34890 355d12da5e55f595c94522b6a0370208 408 Gene3D G3DSA:1.10.540.10 1 117 1.2E-21 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS34890 355d12da5e55f595c94522b6a0370208 408 SUPERFAMILY SSF47203 258 404 1.06E-53 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMALA_RS34890 355d12da5e55f595c94522b6a0370208 408 Gene3D G3DSA:1.20.140.10 224 406 9.7E-58 T 29-03-2018 SMALA_RS34890 355d12da5e55f595c94522b6a0370208 408 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 10 115 1.5E-14 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS34890 355d12da5e55f595c94522b6a0370208 408 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 126 223 6.0E-24 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 SMALA_RS34890 355d12da5e55f595c94522b6a0370208 408 Gene3D G3DSA:2.40.110.10 125 223 5.2E-33 T 29-03-2018 SMALA_RS34890 355d12da5e55f595c94522b6a0370208 408 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 258 402 6.7E-53 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMALA_RS34890 355d12da5e55f595c94522b6a0370208 408 SUPERFAMILY SSF56645 4 234 9.82E-59 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMALA_RS17330 2b44e8a7bdf5baade60ab33b807af6ab 272 PIRSF PIRSF017393 1 272 7.9E-105 T 29-03-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type SMALA_RS17330 2b44e8a7bdf5baade60ab33b807af6ab 272 SUPERFAMILY SSF53335 16 253 3.14E-43 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS17330 2b44e8a7bdf5baade60ab33b807af6ab 272 Pfam PF04672 S-adenosyl methyltransferase 8 272 6.8E-113 T 29-03-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type SMALA_RS17330 2b44e8a7bdf5baade60ab33b807af6ab 272 Gene3D G3DSA:3.40.50.150 2 272 1.1E-54 T 29-03-2018 SMALA_RS11150 e270df7d977f636a4666ec32cb95c366 338 SUPERFAMILY SSF53335 57 225 6.18E-15 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS11150 e270df7d977f636a4666ec32cb95c366 338 Gene3D G3DSA:3.40.50.150 2 266 3.4E-11 T 29-03-2018 SMALA_RS11150 e270df7d977f636a4666ec32cb95c366 338 Pfam PF09243 Mitochondrial small ribosomal subunit Rsm22 55 331 2.0E-100 T 29-03-2018 IPR015324 Ribosomal protein Rsm22-like GO:0006412|GO:0008168 SMALA_RS21005 a489def9f1a33967f4d17f2ebd321794 180 Gene3D G3DSA:3.90.79.10 1 180 1.8E-36 T 29-03-2018 SMALA_RS21005 a489def9f1a33967f4d17f2ebd321794 180 ProSitePatterns PS00893 Nudix box signature. 74 95 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 SMALA_RS21005 a489def9f1a33967f4d17f2ebd321794 180 PRINTS PR00502 NUDIX hydrolase family signature 69 83 1.2E-8 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMALA_RS21005 a489def9f1a33967f4d17f2ebd321794 180 PRINTS PR00502 NUDIX hydrolase family signature 83 98 1.2E-8 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMALA_RS21005 a489def9f1a33967f4d17f2ebd321794 180 SUPERFAMILY SSF55811 3 171 4.74E-38 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMALA_RS21005 a489def9f1a33967f4d17f2ebd321794 180 Pfam PF00293 NUDIX domain 39 151 8.3E-21 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SMALA_RS10120 d22754042f6bad6fb76f66a0bfd0f4bd 1181 Pfam PF02811 PHP domain 8 194 2.7E-46 T 29-03-2018 IPR004013 PHP domain GO:0003824 SMALA_RS10120 d22754042f6bad6fb76f66a0bfd0f4bd 1181 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 6 1059 0.0 T 29-03-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMALA_RS10120 d22754042f6bad6fb76f66a0bfd0f4bd 1181 Gene3D G3DSA:3.20.20.140 2 264 6.6E-47 T 29-03-2018 SMALA_RS10120 d22754042f6bad6fb76f66a0bfd0f4bd 1181 SUPERFAMILY SSF89550 7 92 1.7E-30 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 SMALA_RS10120 d22754042f6bad6fb76f66a0bfd0f4bd 1181 SUPERFAMILY SSF89550 120 268 1.7E-30 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 SMALA_RS10120 d22754042f6bad6fb76f66a0bfd0f4bd 1181 Gene3D G3DSA:2.40.50.140 1001 1097 7.7E-12 T 29-03-2018 SMALA_RS10120 d22754042f6bad6fb76f66a0bfd0f4bd 1181 Pfam PF14579 Helix-hairpin-helix motif 829 917 3.8E-24 T 29-03-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMALA_RS10120 d22754042f6bad6fb76f66a0bfd0f4bd 1181 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 316 756 1.4E-163 T 29-03-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMALA_RS10120 d22754042f6bad6fb76f66a0bfd0f4bd 1181 Gene3D G3DSA:1.10.150.280 807 915 1.2E-7 T 29-03-2018 SMALA_RS10120 d22754042f6bad6fb76f66a0bfd0f4bd 1181 SMART SM00481 7 74 1.3E-30 T 29-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal SMALA_RS38810 48b22f358cde7feaaeac367ff8c9cc20 454 PIRSF PIRSF000521 2 151 1.0E-8 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMALA_RS38810 48b22f358cde7feaaeac367ff8c9cc20 454 PIRSF PIRSF000521 146 447 1.3E-34 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMALA_RS38810 48b22f358cde7feaaeac367ff8c9cc20 454 SUPERFAMILY SSF53383 32 443 6.12E-107 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS38810 48b22f358cde7feaaeac367ff8c9cc20 454 TIGRFAM TIGR00709 dat: 2,4-diaminobutyrate 4-transaminase 28 449 3.6E-126 T 29-03-2018 IPR004637 2,4-diaminobutyrate 4-transaminase GO:0008483|GO:0009058 KEGG: 00260+2.6.1.76|MetaCyc: PWY-6409|MetaCyc: PWY-6562|MetaCyc: PWY-761|MetaCyc: PWY-7855 SMALA_RS38810 48b22f358cde7feaaeac367ff8c9cc20 454 Gene3D G3DSA:3.90.1150.10 330 453 3.0E-28 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS38810 48b22f358cde7feaaeac367ff8c9cc20 454 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 261 297 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMALA_RS38810 48b22f358cde7feaaeac367ff8c9cc20 454 Gene3D G3DSA:3.40.640.10 72 329 3.0E-68 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS38810 48b22f358cde7feaaeac367ff8c9cc20 454 Pfam PF00202 Aminotransferase class-III 44 443 3.2E-87 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMALA_RS29520 7079d7e8d432f67d95e94d5b6a4f0209 559 SUPERFAMILY SSF51905 1 292 3.27E-46 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS29520 7079d7e8d432f67d95e94d5b6a4f0209 559 SUPERFAMILY SSF51905 457 491 3.27E-46 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS29520 7079d7e8d432f67d95e94d5b6a4f0209 559 Pfam PF01593 Flavin containing amine oxidoreductase 16 509 5.2E-15 T 29-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 SMALA_RS29520 7079d7e8d432f67d95e94d5b6a4f0209 559 Gene3D G3DSA:3.50.50.60 1 516 8.1E-33 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS23425 20457298ac76b9d0179fd4d3687e6835 133 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 73 88 1.1E-22 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS23425 20457298ac76b9d0179fd4d3687e6835 133 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 88 103 1.1E-22 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS23425 20457298ac76b9d0179fd4d3687e6835 133 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 38 53 1.1E-22 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS23425 20457298ac76b9d0179fd4d3687e6835 133 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 71 1.1E-22 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS23425 20457298ac76b9d0179fd4d3687e6835 133 SUPERFAMILY SSF46785 21 116 6.44E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS23425 20457298ac76b9d0179fd4d3687e6835 133 ProSitePatterns PS00846 Bacterial regulatory proteins, arsR family signature. 62 80 - T 29-03-2018 IPR018334 ArsR-type transcription regulator, HTH motif GO:0003700|GO:0005622|GO:0006355 SMALA_RS23425 20457298ac76b9d0179fd4d3687e6835 133 Gene3D G3DSA:1.10.10.10 21 119 3.5E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS23425 20457298ac76b9d0179fd4d3687e6835 133 SMART SM00418 36 116 1.7E-28 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS23425 20457298ac76b9d0179fd4d3687e6835 133 Pfam PF01022 Bacterial regulatory protein, arsR family 43 90 4.2E-16 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS10225 9f32b0dea26736cf59f6a0b77bd3b6f1 483 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 17 472 1.3E-115 T 29-03-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMALA_RS10225 9f32b0dea26736cf59f6a0b77bd3b6f1 483 SUPERFAMILY SSF51984 12 106 1.57E-14 T 29-03-2018 SMALA_RS10225 9f32b0dea26736cf59f6a0b77bd3b6f1 483 Gene3D G3DSA:3.40.50.720 2 106 4.4E-20 T 29-03-2018 SMALA_RS10225 9f32b0dea26736cf59f6a0b77bd3b6f1 483 Gene3D G3DSA:3.40.1190.10 108 333 9.1E-57 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMALA_RS10225 9f32b0dea26736cf59f6a0b77bd3b6f1 483 Gene3D G3DSA:3.90.190.20 334 473 5.9E-37 T 29-03-2018 SMALA_RS10225 9f32b0dea26736cf59f6a0b77bd3b6f1 483 Pfam PF08245 Mur ligase middle domain 125 310 1.3E-25 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMALA_RS10225 9f32b0dea26736cf59f6a0b77bd3b6f1 483 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 16 474 33.516 T 29-03-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMALA_RS10225 9f32b0dea26736cf59f6a0b77bd3b6f1 483 SUPERFAMILY SSF53244 331 474 4.88E-39 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 SMALA_RS10225 9f32b0dea26736cf59f6a0b77bd3b6f1 483 SUPERFAMILY SSF53623 120 327 5.23E-48 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMALA_RS10225 9f32b0dea26736cf59f6a0b77bd3b6f1 483 Pfam PF02875 Mur ligase family, glutamate ligase domain 331 399 1.3E-6 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 SMALA_RS16845 a7efb659a7d705af72579361d77e26b1 348 SUPERFAMILY SSF47413 17 78 1.35E-7 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS16845 a7efb659a7d705af72579361d77e26b1 348 Pfam PF10901 Protein of unknown function (DUF2690) 239 331 6.2E-21 T 29-03-2018 IPR021224 Protein of unknown function DUF2690 SMALA_RS16845 a7efb659a7d705af72579361d77e26b1 348 SMART SM00530 21 76 8.4E-9 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS16845 a7efb659a7d705af72579361d77e26b1 348 Pfam PF13560 Helix-turn-helix domain 18 74 8.9E-14 T 29-03-2018 SMALA_RS16845 a7efb659a7d705af72579361d77e26b1 348 Gene3D G3DSA:1.10.260.40 14 78 2.7E-11 T 29-03-2018 SMALA_RS07320 ac1648afdf0130f535e956d392a7922c 264 PRINTS PR00783 Major intrinsic protein family signature 195 217 1.7E-44 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMALA_RS07320 ac1648afdf0130f535e956d392a7922c 264 PRINTS PR00783 Major intrinsic protein family signature 84 103 1.7E-44 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMALA_RS07320 ac1648afdf0130f535e956d392a7922c 264 PRINTS PR00783 Major intrinsic protein family signature 242 262 1.7E-44 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMALA_RS07320 ac1648afdf0130f535e956d392a7922c 264 PRINTS PR00783 Major intrinsic protein family signature 162 180 1.7E-44 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMALA_RS07320 ac1648afdf0130f535e956d392a7922c 264 PRINTS PR00783 Major intrinsic protein family signature 47 71 1.7E-44 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMALA_RS07320 ac1648afdf0130f535e956d392a7922c 264 PRINTS PR00783 Major intrinsic protein family signature 5 24 1.7E-44 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMALA_RS07320 ac1648afdf0130f535e956d392a7922c 264 Gene3D G3DSA:1.20.1080.10 2 264 1.1E-79 T 29-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 SMALA_RS07320 ac1648afdf0130f535e956d392a7922c 264 Pfam PF00230 Major intrinsic protein 6 259 2.6E-45 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMALA_RS07320 ac1648afdf0130f535e956d392a7922c 264 ProSitePatterns PS00221 MIP family signature. 65 73 - T 29-03-2018 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMALA_RS07320 ac1648afdf0130f535e956d392a7922c 264 SUPERFAMILY SSF81338 7 263 1.57E-63 T 29-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 SMALA_RS07320 ac1648afdf0130f535e956d392a7922c 264 TIGRFAM TIGR00861 MIP: MIP family channel proteins 10 259 7.9E-52 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMALA_RS03140 ad4ff090a4defe98d54c0c2e7bfaeed9 790 SUPERFAMILY SSF54665 8 158 3.4E-43 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMALA_RS03140 ad4ff090a4defe98d54c0c2e7bfaeed9 790 Gene3D G3DSA:3.30.365.10 457 623 3.0E-42 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMALA_RS03140 ad4ff090a4defe98d54c0c2e7bfaeed9 790 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 164 719 5.5E-160 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMALA_RS03140 ad4ff090a4defe98d54c0c2e7bfaeed9 790 Gene3D G3DSA:3.30.365.10 279 456 7.3E-39 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMALA_RS03140 ad4ff090a4defe98d54c0c2e7bfaeed9 790 Gene3D G3DSA:3.90.1170.50 1 138 4.9E-37 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMALA_RS03140 ad4ff090a4defe98d54c0c2e7bfaeed9 790 SMART SM01008 24 138 2.0E-47 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMALA_RS03140 ad4ff090a4defe98d54c0c2e7bfaeed9 790 SUPERFAMILY SSF56003 131 782 1.44E-183 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMALA_RS03140 ad4ff090a4defe98d54c0c2e7bfaeed9 790 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 24 138 9.4E-27 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMALA_RS03140 ad4ff090a4defe98d54c0c2e7bfaeed9 790 Gene3D G3DSA:3.30.365.10 624 787 1.0E-43 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMALA_RS03140 ad4ff090a4defe98d54c0c2e7bfaeed9 790 Gene3D G3DSA:3.30.365.10 171 278 1.4E-32 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMALA_RS05505 7a0cb3aa4e4a41cb2569cd82d10dc367 302 Gene3D G3DSA:1.10.10.10 3 85 2.8E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS05505 7a0cb3aa4e4a41cb2569cd82d10dc367 302 SUPERFAMILY SSF53850 96 298 1.25E-39 T 29-03-2018 SMALA_RS05505 7a0cb3aa4e4a41cb2569cd82d10dc367 302 Gene3D G3DSA:3.40.190.10 92 180 3.8E-22 T 29-03-2018 SMALA_RS05505 7a0cb3aa4e4a41cb2569cd82d10dc367 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 5.7E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS05505 7a0cb3aa4e4a41cb2569cd82d10dc367 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 5.7E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS05505 7a0cb3aa4e4a41cb2569cd82d10dc367 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 5.7E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS05505 7a0cb3aa4e4a41cb2569cd82d10dc367 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 66 1.1E-16 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS05505 7a0cb3aa4e4a41cb2569cd82d10dc367 302 Gene3D G3DSA:3.40.190.10 181 273 2.9E-21 T 29-03-2018 SMALA_RS05505 7a0cb3aa4e4a41cb2569cd82d10dc367 302 SUPERFAMILY SSF46785 4 115 1.22E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS05505 7a0cb3aa4e4a41cb2569cd82d10dc367 302 Pfam PF03466 LysR substrate binding domain 95 297 2.5E-43 T 29-03-2018 IPR005119 LysR, substrate-binding SMALA_RS38920 688df84f0fecab3a06648b74b7bf7a32 262 SUPERFAMILY SSF56281 2 255 1.05E-29 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS38920 688df84f0fecab3a06648b74b7bf7a32 262 Gene3D G3DSA:3.60.15.10 10 261 1.1E-29 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS38920 688df84f0fecab3a06648b74b7bf7a32 262 Pfam PF00753 Metallo-beta-lactamase superfamily 19 239 3.1E-16 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS38920 688df84f0fecab3a06648b74b7bf7a32 262 SMART SM00849 20 251 1.7E-15 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS01445 e9d4b6fc0e59eb2f614475ef666f0c08 319 SMART SM00829 13 316 1.5E-14 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS01445 e9d4b6fc0e59eb2f614475ef666f0c08 319 SUPERFAMILY SSF50129 3 152 1.07E-32 T 29-03-2018 IPR011032 GroES-like SMALA_RS01445 e9d4b6fc0e59eb2f614475ef666f0c08 319 Gene3D G3DSA:3.90.180.10 1 319 1.6E-64 T 29-03-2018 SMALA_RS01445 e9d4b6fc0e59eb2f614475ef666f0c08 319 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 30 91 5.5E-8 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS01445 e9d4b6fc0e59eb2f614475ef666f0c08 319 Pfam PF13602 Zinc-binding dehydrogenase 190 316 1.7E-22 T 29-03-2018 SMALA_RS01445 e9d4b6fc0e59eb2f614475ef666f0c08 319 SUPERFAMILY SSF51735 120 293 4.54E-31 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS14555 884cd4308f371a0fd9be7c67fd89986d 645 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 204 370 8.1E-32 T 29-03-2018 IPR000160 GGDEF domain SMALA_RS14555 884cd4308f371a0fd9be7c67fd89986d 645 Pfam PF00990 Diguanylate cyclase, GGDEF domain 208 367 1.2E-39 T 29-03-2018 IPR000160 GGDEF domain SMALA_RS14555 884cd4308f371a0fd9be7c67fd89986d 645 SMART SM00267 196 372 3.3E-48 T 29-03-2018 IPR000160 GGDEF domain SMALA_RS14555 884cd4308f371a0fd9be7c67fd89986d 645 SUPERFAMILY SSF55073 213 374 6.04E-40 T 29-03-2018 IPR029787 Nucleotide cyclase SMALA_RS14555 884cd4308f371a0fd9be7c67fd89986d 645 SUPERFAMILY SSF141868 389 639 1.83E-83 T 29-03-2018 IPR001633 EAL domain SMALA_RS14555 884cd4308f371a0fd9be7c67fd89986d 645 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 87 202 7.3E-12 T 29-03-2018 IPR000014 PAS domain SMALA_RS14555 884cd4308f371a0fd9be7c67fd89986d 645 Gene3D G3DSA:3.30.70.270 206 379 3.3E-56 T 29-03-2018 SMALA_RS14555 884cd4308f371a0fd9be7c67fd89986d 645 Gene3D G3DSA:3.20.20.450 380 643 5.0E-107 T 29-03-2018 IPR001633 EAL domain SMALA_RS14555 884cd4308f371a0fd9be7c67fd89986d 645 SUPERFAMILY SSF55785 87 183 1.01E-13 T 29-03-2018 IPR000014 PAS domain SMALA_RS14555 884cd4308f371a0fd9be7c67fd89986d 645 SMART SM00091 85 151 1.4E-4 T 29-03-2018 IPR000014 PAS domain SMALA_RS14555 884cd4308f371a0fd9be7c67fd89986d 645 Pfam PF00563 EAL domain 389 628 1.7E-68 T 29-03-2018 IPR001633 EAL domain SMALA_RS14555 884cd4308f371a0fd9be7c67fd89986d 645 Gene3D G3DSA:3.30.450.20 85 205 2.5E-19 T 29-03-2018 SMALA_RS14555 884cd4308f371a0fd9be7c67fd89986d 645 Pfam PF13188 PAS domain 87 143 2.6E-5 T 29-03-2018 IPR000014 PAS domain SMALA_RS14555 884cd4308f371a0fd9be7c67fd89986d 645 SMART SM00052 382 633 7.4E-108 T 29-03-2018 IPR001633 EAL domain SMALA_RS21760 ef4f9750c5f23635b93cbeaef5fc9b23 218 Gene3D G3DSA:3.40.50.1000 76 218 7.5E-33 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS21760 ef4f9750c5f23635b93cbeaef5fc9b23 218 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 87 169 6.5E-6 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMALA_RS21760 ef4f9750c5f23635b93cbeaef5fc9b23 218 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 186 7.0E-27 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS21760 ef4f9750c5f23635b93cbeaef5fc9b23 218 Gene3D G3DSA:1.10.150.240 18 75 2.0E-20 T 29-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 SMALA_RS21760 ef4f9750c5f23635b93cbeaef5fc9b23 218 SUPERFAMILY SSF56784 3 213 1.36E-53 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS21760 ef4f9750c5f23635b93cbeaef5fc9b23 218 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 63 187 1.3E-17 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMALA_RS32870 0f1272e98acb71b51a547a0c5fc39995 735 SUPERFAMILY SSF54211 520 636 1.24E-35 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SMALA_RS32870 0f1272e98acb71b51a547a0c5fc39995 735 Pfam PF14492 Elongation Factor G, domain II 443 514 1.7E-23 T 29-03-2018 SMALA_RS32870 0f1272e98acb71b51a547a0c5fc39995 735 SUPERFAMILY SSF52540 21 311 1.24E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS32870 0f1272e98acb71b51a547a0c5fc39995 735 Gene3D G3DSA:3.30.70.870 439 530 4.6E-19 T 29-03-2018 SMALA_RS32870 0f1272e98acb71b51a547a0c5fc39995 735 Gene3D G3DSA:2.40.30.10 318 438 3.5E-29 T 29-03-2018 SMALA_RS32870 0f1272e98acb71b51a547a0c5fc39995 735 SMART SM00889 519 637 4.0E-58 T 29-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 SMALA_RS32870 0f1272e98acb71b51a547a0c5fc39995 735 Pfam PF03764 Elongation factor G, domain IV 519 636 1.1E-39 T 29-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 SMALA_RS32870 0f1272e98acb71b51a547a0c5fc39995 735 Pfam PF03144 Elongation factor Tu domain 2 353 429 1.1E-9 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 SMALA_RS32870 0f1272e98acb71b51a547a0c5fc39995 735 Pfam PF00009 Elongation factor Tu GTP binding domain 24 267 8.2E-27 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMALA_RS32870 0f1272e98acb71b51a547a0c5fc39995 735 Pfam PF00679 Elongation factor G C-terminus 640 726 1.4E-21 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like SMALA_RS32870 0f1272e98acb71b51a547a0c5fc39995 735 Gene3D G3DSA:3.30.230.10 531 652 2.4E-39 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SMALA_RS32870 0f1272e98acb71b51a547a0c5fc39995 735 SUPERFAMILY SSF54980 640 731 4.7E-20 T 29-03-2018 IPR035647 EF-G domain III/V-like SMALA_RS32870 0f1272e98acb71b51a547a0c5fc39995 735 SUPERFAMILY SSF54980 443 520 1.76E-17 T 29-03-2018 IPR035647 EF-G domain III/V-like SMALA_RS32870 0f1272e98acb71b51a547a0c5fc39995 735 SMART SM00838 639 727 6.5E-17 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like SMALA_RS32870 0f1272e98acb71b51a547a0c5fc39995 735 PRINTS PR00315 GTP-binding elongation factor signature 26 39 9.8E-6 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMALA_RS32870 0f1272e98acb71b51a547a0c5fc39995 735 PRINTS PR00315 GTP-binding elongation factor signature 92 102 9.8E-6 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMALA_RS32870 0f1272e98acb71b51a547a0c5fc39995 735 PRINTS PR00315 GTP-binding elongation factor signature 108 119 9.8E-6 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMALA_RS32870 0f1272e98acb71b51a547a0c5fc39995 735 Gene3D G3DSA:3.40.50.300 16 317 6.3E-36 T 29-03-2018 SMALA_RS32870 0f1272e98acb71b51a547a0c5fc39995 735 SUPERFAMILY SSF50447 327 440 1.36E-22 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain SMALA_RS32870 0f1272e98acb71b51a547a0c5fc39995 735 Gene3D G3DSA:3.30.70.240 653 731 7.2E-21 T 29-03-2018 SMALA_RS26830 c64bbf396d8351e1ebadd28013c1ae8a 362 Gene3D G3DSA:3.40.50.1100 152 344 2.3E-52 T 29-03-2018 SMALA_RS26830 c64bbf396d8351e1ebadd28013c1ae8a 362 TIGRFAM TIGR00260 thrC: threonine synthase 14 336 4.7E-95 T 29-03-2018 IPR004450 Threonine synthase-like SMALA_RS26830 c64bbf396d8351e1ebadd28013c1ae8a 362 SUPERFAMILY SSF53686 8 343 5.37E-102 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMALA_RS26830 c64bbf396d8351e1ebadd28013c1ae8a 362 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 31 329 5.2E-71 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMALA_RS26830 c64bbf396d8351e1ebadd28013c1ae8a 362 PIRSF PIRSF038945 2 361 6.5E-164 T 29-03-2018 IPR026260 Threonine synthase, bacterial/archaeal GO:0004795|GO:0009088 KEGG: 00260+4.2.3.1|KEGG: 00750+4.2.3.1 SMALA_RS26830 c64bbf396d8351e1ebadd28013c1ae8a 362 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 58 71 - T 29-03-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 SMALA_RS26830 c64bbf396d8351e1ebadd28013c1ae8a 362 Gene3D G3DSA:3.40.50.1100 43 151 2.5E-24 T 29-03-2018 SMALA_RS12575 db511787f42fb2b3c866f932f26d0ae6 250 Pfam PF07729 FCD domain 92 213 1.1E-20 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS12575 db511787f42fb2b3c866f932f26d0ae6 250 SMART SM00345 7 66 1.7E-20 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS12575 db511787f42fb2b3c866f932f26d0ae6 250 SUPERFAMILY SSF48008 89 221 2.62E-22 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS12575 db511787f42fb2b3c866f932f26d0ae6 250 SUPERFAMILY SSF46785 4 81 8.51E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS12575 db511787f42fb2b3c866f932f26d0ae6 250 SMART SM00895 92 214 4.7E-19 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS12575 db511787f42fb2b3c866f932f26d0ae6 250 Gene3D G3DSA:1.10.10.10 2 68 1.2E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS12575 db511787f42fb2b3c866f932f26d0ae6 250 Gene3D G3DSA:1.20.120.530 73 228 5.5E-26 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS12575 db511787f42fb2b3c866f932f26d0ae6 250 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 56 9.5E-8 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS12575 db511787f42fb2b3c866f932f26d0ae6 250 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 26 40 9.5E-8 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS12575 db511787f42fb2b3c866f932f26d0ae6 250 Pfam PF00392 Bacterial regulatory proteins, gntR family 5 66 1.1E-19 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS14755 927a241367971656f253d1be3c0cc1e5 249 SMART SM00421 189 238 2.2E-4 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS14755 927a241367971656f253d1be3c0cc1e5 249 SUPERFAMILY SSF46894 189 245 1.67E-10 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS14755 927a241367971656f253d1be3c0cc1e5 249 Pfam PF00196 Bacterial regulatory proteins, luxR family 189 234 8.5E-6 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS14755 927a241367971656f253d1be3c0cc1e5 249 Gene3D G3DSA:1.10.10.10 126 248 3.6E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS05295 2b18cc47285b6649a1000075ff621d6a 335 SUPERFAMILY SSF51735 113 296 9.65E-42 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS05295 2b18cc47285b6649a1000075ff621d6a 335 Gene3D G3DSA:3.40.50.720 8 120 2.0E-16 T 29-03-2018 SMALA_RS05295 2b18cc47285b6649a1000075ff621d6a 335 SUPERFAMILY SSF52283 38 146 7.53E-13 T 29-03-2018 SMALA_RS05295 2b18cc47285b6649a1000075ff621d6a 335 Gene3D G3DSA:3.40.50.720 121 297 1.3E-44 T 29-03-2018 SMALA_RS05295 2b18cc47285b6649a1000075ff621d6a 335 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 121 295 5.2E-45 T 29-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 SMALA_RS05295 2b18cc47285b6649a1000075ff621d6a 335 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 31 325 3.3E-6 T 29-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 SMALA_RS01815 205f71f6d22aab39600606c006d2ab00 534 SUPERFAMILY SSF51905 13 372 4.1E-34 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS01815 205f71f6d22aab39600606c006d2ab00 534 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 15 337 2.4E-52 T 29-03-2018 SMALA_RS01815 205f71f6d22aab39600606c006d2ab00 534 Gene3D G3DSA:3.50.50.60 203 395 1.8E-11 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS01815 205f71f6d22aab39600606c006d2ab00 534 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 189 214 2.9E-5 T 29-03-2018 SMALA_RS01815 205f71f6d22aab39600606c006d2ab00 534 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 13 35 2.9E-5 T 29-03-2018 SMALA_RS01815 205f71f6d22aab39600606c006d2ab00 534 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 152 161 2.9E-5 T 29-03-2018 SMALA_RS01815 205f71f6d22aab39600606c006d2ab00 534 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 14 33 7.9E-10 T 29-03-2018 SMALA_RS01815 205f71f6d22aab39600606c006d2ab00 534 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 318 340 7.9E-10 T 29-03-2018 SMALA_RS01815 205f71f6d22aab39600606c006d2ab00 534 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 149 167 7.9E-10 T 29-03-2018 SMALA_RS01815 205f71f6d22aab39600606c006d2ab00 534 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 189 207 7.9E-10 T 29-03-2018 SMALA_RS01815 205f71f6d22aab39600606c006d2ab00 534 Gene3D G3DSA:3.50.50.60 6 202 2.2E-28 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS23225 3b5b8f15914cf9cb487dcafe1d48a330 870 Gene3D G3DSA:3.20.20.70 479 847 1.3E-51 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS23225 3b5b8f15914cf9cb487dcafe1d48a330 870 Gene3D G3DSA:3.20.20.70 16 391 8.7E-37 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS23225 3b5b8f15914cf9cb487dcafe1d48a330 870 Hamap MF_01611 FO synthase subunit 1 [cofG]. 77 408 50.658 T 29-03-2018 IPR019939 CofG family GO:0009108|GO:0016765|GO:0051539 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 SMALA_RS23225 3b5b8f15914cf9cb487dcafe1d48a330 870 TIGRFAM TIGR03550 F420_cofG: 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofG subunit 78 406 2.6E-144 T 29-03-2018 IPR019939 CofG family GO:0009108|GO:0016765|GO:0051539 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 SMALA_RS23225 3b5b8f15914cf9cb487dcafe1d48a330 870 Hamap MF_01612 FO synthase subunit 2 [cofH]. 487 847 48.761 T 29-03-2018 IPR019940 CofH family GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 SMALA_RS23225 3b5b8f15914cf9cb487dcafe1d48a330 870 SMART SM00729 81 318 2.8E-6 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 SMALA_RS23225 3b5b8f15914cf9cb487dcafe1d48a330 870 SUPERFAMILY SSF102114 40 383 5.62E-39 T 29-03-2018 SMALA_RS23225 3b5b8f15914cf9cb487dcafe1d48a330 870 TIGRFAM TIGR00423 TIGR00423: radical SAM domain protein, CofH subfamily 536 843 2.5E-108 T 29-03-2018 IPR020050 FO synthase, subunit 2 GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 SMALA_RS23225 3b5b8f15914cf9cb487dcafe1d48a330 870 Pfam PF04055 Radical SAM superfamily 544 717 7.0E-16 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 SMALA_RS23225 3b5b8f15914cf9cb487dcafe1d48a330 870 Pfam PF04055 Radical SAM superfamily 85 267 9.3E-15 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 SMALA_RS23225 3b5b8f15914cf9cb487dcafe1d48a330 870 SUPERFAMILY SSF102114 499 810 5.62E-50 T 29-03-2018 SMALA_RS23225 3b5b8f15914cf9cb487dcafe1d48a330 870 TIGRFAM TIGR03551 F420_cofH: 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofH subunit 502 846 2.3E-162 T 29-03-2018 IPR019940 CofH family GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 SMALA_RS19755 8e7660280174f0c90a615794ada6fc37 211 Pfam PF12089 Transmembrane domain of unknown function (DUF3566) 91 209 2.5E-43 T 29-03-2018 IPR021949 Domain of unknown function DUF3566. transmembrane SMALA_RS23470 494715e0b58b8a185ed50dfacef0767c 401 Gene3D G3DSA:3.30.420.40 7 229 1.4E-10 T 29-03-2018 SMALA_RS23470 494715e0b58b8a185ed50dfacef0767c 401 SUPERFAMILY SSF53067 131 399 3.51E-20 T 29-03-2018 SMALA_RS23470 494715e0b58b8a185ed50dfacef0767c 401 SUPERFAMILY SSF53067 21 36 3.51E-20 T 29-03-2018 SMALA_RS23470 494715e0b58b8a185ed50dfacef0767c 401 Pfam PF00480 ROK family 281 398 6.2E-7 T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 SMALA_RS23470 494715e0b58b8a185ed50dfacef0767c 401 Gene3D G3DSA:3.30.420.40 230 401 2.7E-27 T 29-03-2018 SMALA_RS35435 19ce2b8b19b4da5d2959d5bd96f0e26f 269 SUPERFAMILY SSF100950 91 250 9.84E-29 T 29-03-2018 SMALA_RS35435 19ce2b8b19b4da5d2959d5bd96f0e26f 269 Pfam PF00455 DeoR C terminal sensor domain 91 248 5.1E-43 T 29-03-2018 IPR014036 DeoR C-terminal sensor domain SMALA_RS35435 19ce2b8b19b4da5d2959d5bd96f0e26f 269 SUPERFAMILY SSF46785 21 75 4.28E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS35435 19ce2b8b19b4da5d2959d5bd96f0e26f 269 SMART SM01134 88 249 1.7E-62 T 29-03-2018 SMALA_RS35435 19ce2b8b19b4da5d2959d5bd96f0e26f 269 ProSitePatterns PS00894 DeoR-type HTH domain signature. 22 56 - T 29-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 SMALA_RS35435 19ce2b8b19b4da5d2959d5bd96f0e26f 269 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 40 54 4.0E-8 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMALA_RS35435 19ce2b8b19b4da5d2959d5bd96f0e26f 269 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 54 72 4.0E-8 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMALA_RS35435 19ce2b8b19b4da5d2959d5bd96f0e26f 269 Pfam PF08220 DeoR-like helix-turn-helix domain 22 75 9.5E-16 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMALA_RS35435 19ce2b8b19b4da5d2959d5bd96f0e26f 269 Gene3D G3DSA:3.40.50.1360 83 246 8.3E-40 T 29-03-2018 SMALA_RS35435 19ce2b8b19b4da5d2959d5bd96f0e26f 269 SMART SM00420 22 74 1.9E-15 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMALA_RS35435 19ce2b8b19b4da5d2959d5bd96f0e26f 269 Gene3D G3DSA:1.10.10.10 5 82 7.7E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS22365 b3d660da7c06d4654cf82ef4d3e8d404 221 SUPERFAMILY SSF51735 1 206 1.03E-36 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS22365 b3d660da7c06d4654cf82ef4d3e8d404 221 Gene3D G3DSA:3.40.50.720 2 221 1.5E-29 T 29-03-2018 SMALA_RS22365 b3d660da7c06d4654cf82ef4d3e8d404 221 Pfam PF13460 NAD(P)H-binding 7 194 6.0E-42 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS42710 ff051f3fffeae76135e348c751e66b61 577 SUPERFAMILY SSF161098 313 574 4.11E-38 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS42710 ff051f3fffeae76135e348c751e66b61 577 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 405 569 7.5E-7 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS42710 ff051f3fffeae76135e348c751e66b61 577 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 100 293 2.1E-11 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS42710 ff051f3fffeae76135e348c751e66b61 577 SUPERFAMILY SSF161098 26 294 3.64E-43 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS42710 ff051f3fffeae76135e348c751e66b61 577 Gene3D G3DSA:1.10.3720.10 27 299 8.9E-33 T 29-03-2018 SMALA_RS42710 ff051f3fffeae76135e348c751e66b61 577 Gene3D G3DSA:1.10.3720.10 316 575 2.5E-26 T 29-03-2018 SMALA_RS30865 322c3ca89e801ecd98a75b36c886bb4e 215 TIGRFAM TIGR00164 PS_decarb_rel: phosphatidylserine decarboxylase homolog 43 212 5.7E-53 T 29-03-2018 IPR033175 Phosphatidylserine decarboxylase, archaeal-type KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 SMALA_RS30865 322c3ca89e801ecd98a75b36c886bb4e 215 Hamap MF_00664 Phosphatidylserine decarboxylase proenzyme [psd]. 14 215 32.572 T 29-03-2018 IPR033175 Phosphatidylserine decarboxylase, archaeal-type KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 SMALA_RS30865 322c3ca89e801ecd98a75b36c886bb4e 215 Pfam PF02666 Phosphatidylserine decarboxylase 56 209 5.5E-30 T 29-03-2018 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 SMALA_RS30865 322c3ca89e801ecd98a75b36c886bb4e 215 Gene3D G3DSA:2.40.50.100 101 211 8.0E-4 T 29-03-2018 SMALA_RS40115 923511375e9f1bf2c907ef563053bd9a 354 Gene3D G3DSA:3.40.50.2300 71 185 5.6E-23 T 29-03-2018 SMALA_RS40115 923511375e9f1bf2c907ef563053bd9a 354 SUPERFAMILY SSF53822 88 347 1.32E-56 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SMALA_RS40115 923511375e9f1bf2c907ef563053bd9a 354 SUPERFAMILY SSF47413 14 72 2.75E-15 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS40115 923511375e9f1bf2c907ef563053bd9a 354 Pfam PF13377 Periplasmic binding protein-like domain 186 344 1.2E-40 T 29-03-2018 SMALA_RS40115 923511375e9f1bf2c907ef563053bd9a 354 SMART SM00354 14 84 1.1E-16 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS40115 923511375e9f1bf2c907ef563053bd9a 354 Gene3D G3DSA:1.10.260.40 15 70 2.3E-21 T 29-03-2018 SMALA_RS40115 923511375e9f1bf2c907ef563053bd9a 354 Pfam PF00356 Bacterial regulatory proteins, lacI family 17 61 7.0E-13 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS40115 923511375e9f1bf2c907ef563053bd9a 354 Gene3D G3DSA:3.40.50.2300 186 347 7.1E-48 T 29-03-2018 SMALA_RS17395 05539e38a3c73a9da8ccab5efec0389e 257 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS17395 05539e38a3c73a9da8ccab5efec0389e 257 Pfam PF00005 ABC transporter 12 159 4.1E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS17395 05539e38a3c73a9da8ccab5efec0389e 257 SUPERFAMILY SSF52540 1 221 1.2E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS17395 05539e38a3c73a9da8ccab5efec0389e 257 Gene3D G3DSA:3.40.50.300 1 232 1.2E-64 T 29-03-2018 SMALA_RS17395 05539e38a3c73a9da8ccab5efec0389e 257 SMART SM00382 20 217 2.8E-18 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS16810 410a3ebca552a425fae3187246565d72 528 Gene3D G3DSA:4.10.450.10 40 106 9.7E-14 T 29-03-2018 SMALA_RS16810 410a3ebca552a425fae3187246565d72 528 Pfam PF05199 GMC oxidoreductase 360 500 4.8E-37 T 29-03-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 SMALA_RS16810 410a3ebca552a425fae3187246565d72 528 Pfam PF00732 GMC oxidoreductase 7 290 3.4E-58 T 29-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 SMALA_RS16810 410a3ebca552a425fae3187246565d72 528 SUPERFAMILY SSF54373 284 448 2.16E-41 T 29-03-2018 SMALA_RS16810 410a3ebca552a425fae3187246565d72 528 SUPERFAMILY SSF51905 6 277 4.79E-72 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS16810 410a3ebca552a425fae3187246565d72 528 SUPERFAMILY SSF51905 444 508 4.79E-72 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS16810 410a3ebca552a425fae3187246565d72 528 Gene3D G3DSA:3.30.560.10 107 463 2.7E-85 T 29-03-2018 SMALA_RS16810 410a3ebca552a425fae3187246565d72 528 PIRSF PIRSF000137 309 516 1.5E-44 T 29-03-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 SMALA_RS16810 410a3ebca552a425fae3187246565d72 528 PIRSF PIRSF000137 1 315 2.2E-78 T 29-03-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 SMALA_RS16810 410a3ebca552a425fae3187246565d72 528 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 248 262 - T 29-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 SMALA_RS19245 e57800e8dc47ee6d4c948c31bd0fd586 262 SUPERFAMILY SSF55874 68 166 1.1E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS19245 e57800e8dc47ee6d4c948c31bd0fd586 262 Pfam PF13581 Histidine kinase-like ATPase domain 46 158 3.0E-13 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS19245 e57800e8dc47ee6d4c948c31bd0fd586 262 Gene3D G3DSA:3.30.565.10 33 174 2.7E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS22910 ed450e0a975fb4d0e7f8ac0b5c273034 332 Pfam PF01522 Polysaccharide deacetylase 146 265 5.6E-20 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 SMALA_RS22910 ed450e0a975fb4d0e7f8ac0b5c273034 332 Gene3D G3DSA:3.20.20.370 140 332 3.4E-28 T 29-03-2018 SMALA_RS22910 ed450e0a975fb4d0e7f8ac0b5c273034 332 SUPERFAMILY SSF88713 136 331 2.16E-30 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 SMALA_RS23685 0f154077616beeb74a0a6d709b2d189e 314 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 2 295 1.6E-99 T 29-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 SMALA_RS23685 0f154077616beeb74a0a6d709b2d189e 314 Gene3D G3DSA:2.20.150.10 9 43 8.9E-16 T 29-03-2018 IPR023314 Tagatose-6-phosphate kinase/1-phosphofructokinase N-terminal domain SMALA_RS23685 0f154077616beeb74a0a6d709b2d189e 314 Pfam PF00294 pfkB family carbohydrate kinase 25 290 1.5E-38 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB SMALA_RS23685 0f154077616beeb74a0a6d709b2d189e 314 Gene3D G3DSA:3.40.1190.20 44 300 5.4E-42 T 29-03-2018 IPR029056 Ribokinase-like SMALA_RS23685 0f154077616beeb74a0a6d709b2d189e 314 PIRSF PIRSF000535 1 299 1.4E-74 T 29-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 SMALA_RS23685 0f154077616beeb74a0a6d709b2d189e 314 SUPERFAMILY SSF53613 1 291 2.03E-60 T 29-03-2018 IPR029056 Ribokinase-like SMALA_RS23685 0f154077616beeb74a0a6d709b2d189e 314 TIGRFAM TIGR03828 pfkB: 1-phosphofructokinase 2 295 2.8E-99 T 29-03-2018 IPR022463 Fructose 1-phosphate kinase GO:0008662 KEGG: 00051+2.7.1.56 SMALA_RS30940 015d957d1d3846abdd0525f758a50cda 446 Pfam PF07687 Peptidase dimerisation domain 203 329 1.2E-13 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain SMALA_RS30940 015d957d1d3846abdd0525f758a50cda 446 Gene3D G3DSA:3.30.70.360 209 328 7.0E-19 T 29-03-2018 SMALA_RS30940 015d957d1d3846abdd0525f758a50cda 446 PIRSF PIRSF036696 10 255 6.6E-30 T 29-03-2018 SMALA_RS30940 015d957d1d3846abdd0525f758a50cda 446 PIRSF PIRSF036696 287 445 3.3E-9 T 29-03-2018 SMALA_RS30940 015d957d1d3846abdd0525f758a50cda 446 Gene3D G3DSA:3.40.630.10 329 446 1.5E-11 T 29-03-2018 SMALA_RS30940 015d957d1d3846abdd0525f758a50cda 446 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 84 93 - T 29-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 SMALA_RS30940 015d957d1d3846abdd0525f758a50cda 446 Gene3D G3DSA:3.40.630.10 8 208 6.8E-44 T 29-03-2018 SMALA_RS30940 015d957d1d3846abdd0525f758a50cda 446 SUPERFAMILY SSF53187 13 205 1.61E-54 T 29-03-2018 SMALA_RS30940 015d957d1d3846abdd0525f758a50cda 446 SUPERFAMILY SSF53187 356 445 1.61E-54 T 29-03-2018 SMALA_RS30940 015d957d1d3846abdd0525f758a50cda 446 SUPERFAMILY SSF55031 205 247 9.52E-11 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain SMALA_RS30940 015d957d1d3846abdd0525f758a50cda 446 SUPERFAMILY SSF55031 295 355 9.52E-11 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain SMALA_RS30940 015d957d1d3846abdd0525f758a50cda 446 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 119 158 - T 29-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 SMALA_RS30940 015d957d1d3846abdd0525f758a50cda 446 Pfam PF01546 Peptidase family M20/M25/M40 85 444 2.8E-39 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 SMALA_RS27500 7772f012f8e69e63f7814d33f5d35d4e 284 SUPERFAMILY SSF88659 98 155 1.55E-10 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS27500 7772f012f8e69e63f7814d33f5d35d4e 284 Gene3D G3DSA:1.10.10.10 104 163 2.1E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS27500 7772f012f8e69e63f7814d33f5d35d4e 284 SUPERFAMILY SSF88946 7 84 1.06E-12 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS27500 7772f012f8e69e63f7814d33f5d35d4e 284 Gene3D G3DSA:3.10.450.50 164 283 7.6E-20 T 29-03-2018 SMALA_RS27500 7772f012f8e69e63f7814d33f5d35d4e 284 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 7 155 3.9E-15 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS27500 7772f012f8e69e63f7814d33f5d35d4e 284 Pfam PF04542 Sigma-70 region 2 7 68 6.2E-14 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS27500 7772f012f8e69e63f7814d33f5d35d4e 284 TIGRFAM TIGR02957 SigX4: RNA polymerase sigma-70 factor, TIGR02957 family 7 282 2.5E-99 T 29-03-2018 IPR014303 RNA polymerase sigma-70, ECF type SMALA_RS27500 7772f012f8e69e63f7814d33f5d35d4e 284 Pfam PF08281 Sigma-70, region 4 102 153 4.8E-10 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS27500 7772f012f8e69e63f7814d33f5d35d4e 284 Gene3D G3DSA:1.10.1740.10 4 74 1.2E-13 T 29-03-2018 SMALA_RS27500 7772f012f8e69e63f7814d33f5d35d4e 284 SUPERFAMILY SSF54427 169 283 1.53E-14 T 29-03-2018 IPR032710 NTF2-like domain SMALA_RS22995 1abcba2fd1039293938e58f3ee3da096 400 SUPERFAMILY SSF56601 59 380 2.32E-72 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMALA_RS22995 1abcba2fd1039293938e58f3ee3da096 400 Pfam PF00144 Beta-lactamase 61 381 7.4E-55 T 29-03-2018 IPR001466 Beta-lactamase-related SMALA_RS22995 1abcba2fd1039293938e58f3ee3da096 400 Gene3D G3DSA:3.40.710.10 57 395 1.7E-72 T 29-03-2018 SMALA_RS13555 81b29038988878022d6594fd38baad2a 193 Gene3D G3DSA:1.10.260.40 46 166 1.0E-8 T 29-03-2018 SMALA_RS13555 81b29038988878022d6594fd38baad2a 193 SUPERFAMILY SSF46689 5 84 5.64E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS13555 81b29038988878022d6594fd38baad2a 193 Gene3D G3DSA:1.10.10.60 1 45 4.3E-18 T 29-03-2018 SMALA_RS13555 81b29038988878022d6594fd38baad2a 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 4.8E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS13555 81b29038988878022d6594fd38baad2a 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 4.8E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS13555 81b29038988878022d6594fd38baad2a 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 59 1.0E-14 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS16795 20f27c13c05ca37bbddea41aa31f64be 325 SUPERFAMILY SSF53850 40 325 7.6E-53 T 29-03-2018 SMALA_RS16795 20f27c13c05ca37bbddea41aa31f64be 325 Gene3D G3DSA:3.40.190.10 176 325 9.6E-27 T 29-03-2018 SMALA_RS16795 20f27c13c05ca37bbddea41aa31f64be 325 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 43 314 8.1E-45 T 29-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 SMALA_RS16795 20f27c13c05ca37bbddea41aa31f64be 325 Gene3D G3DSA:3.40.190.10 37 164 2.3E-14 T 29-03-2018 SMALA_RS08250 f646c52727f682d8dbee85c9bf2a53af 172 SUPERFAMILY SSF159234 57 163 6.41E-16 T 29-03-2018 IPR007295 Domain of unknown function DUF402 SMALA_RS08250 f646c52727f682d8dbee85c9bf2a53af 172 Gene3D G3DSA:2.40.380.10 7 166 8.3E-30 T 29-03-2018 IPR007295 Domain of unknown function DUF402 SMALA_RS08250 f646c52727f682d8dbee85c9bf2a53af 172 Pfam PF04167 Protein of unknown function (DUF402) 58 121 4.3E-14 T 29-03-2018 IPR007295 Domain of unknown function DUF402 SMALA_RS10655 213dcf3989b883eab5bfe10fff1664b7 462 SUPERFAMILY SSF51905 7 366 7.0E-60 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS10655 213dcf3989b883eab5bfe10fff1664b7 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 259 273 3.3E-65 T 29-03-2018 SMALA_RS10655 213dcf3989b883eab5bfe10fff1664b7 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 42 57 3.3E-65 T 29-03-2018 SMALA_RS10655 213dcf3989b883eab5bfe10fff1664b7 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 301 308 3.3E-65 T 29-03-2018 SMALA_RS10655 213dcf3989b883eab5bfe10fff1664b7 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 10 32 3.3E-65 T 29-03-2018 SMALA_RS10655 213dcf3989b883eab5bfe10fff1664b7 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 174 199 3.3E-65 T 29-03-2018 SMALA_RS10655 213dcf3989b883eab5bfe10fff1664b7 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 424 444 3.3E-65 T 29-03-2018 SMALA_RS10655 213dcf3989b883eab5bfe10fff1664b7 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 138 147 3.3E-65 T 29-03-2018 SMALA_RS10655 213dcf3989b883eab5bfe10fff1664b7 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 337 358 3.3E-65 T 29-03-2018 SMALA_RS10655 213dcf3989b883eab5bfe10fff1664b7 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 402 417 3.3E-65 T 29-03-2018 SMALA_RS10655 213dcf3989b883eab5bfe10fff1664b7 462 Gene3D G3DSA:3.30.390.30 328 456 6.3E-31 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SMALA_RS10655 213dcf3989b883eab5bfe10fff1664b7 462 SUPERFAMILY SSF55424 338 459 1.49E-28 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SMALA_RS10655 213dcf3989b883eab5bfe10fff1664b7 462 PIRSF PIRSF000350 1 438 5.9E-70 T 29-03-2018 SMALA_RS10655 213dcf3989b883eab5bfe10fff1664b7 462 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 9 459 1.6E-139 T 29-03-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 SMALA_RS10655 213dcf3989b883eab5bfe10fff1664b7 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 135 153 2.4E-34 T 29-03-2018 SMALA_RS10655 213dcf3989b883eab5bfe10fff1664b7 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 174 192 2.4E-34 T 29-03-2018 SMALA_RS10655 213dcf3989b883eab5bfe10fff1664b7 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 258 274 2.4E-34 T 29-03-2018 SMALA_RS10655 213dcf3989b883eab5bfe10fff1664b7 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 2.4E-34 T 29-03-2018 SMALA_RS10655 213dcf3989b883eab5bfe10fff1664b7 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 286 308 2.4E-34 T 29-03-2018 SMALA_RS10655 213dcf3989b883eab5bfe10fff1664b7 462 Gene3D G3DSA:3.50.50.60 4 165 4.7E-28 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS10655 213dcf3989b883eab5bfe10fff1664b7 462 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 9 321 5.7E-69 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS10655 213dcf3989b883eab5bfe10fff1664b7 462 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 43 53 - T 29-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 SMALA_RS10655 213dcf3989b883eab5bfe10fff1664b7 462 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 341 449 2.0E-23 T 29-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 SMALA_RS10655 213dcf3989b883eab5bfe10fff1664b7 462 Gene3D G3DSA:3.40.50.720 166 327 3.8E-35 T 29-03-2018 SMALA_RS12195 255373b0d89d10f920d91ca8d96fb318 213 SUPERFAMILY SSF51161 58 207 1.08E-40 T 29-03-2018 IPR011004 Trimeric LpxA-like SMALA_RS12195 255373b0d89d10f920d91ca8d96fb318 213 Gene3D G3DSA:2.160.10.10 21 210 4.5E-38 T 29-03-2018 SMALA_RS12195 255373b0d89d10f920d91ca8d96fb318 213 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 116 149 1.2E-6 T 29-03-2018 IPR001451 Hexapeptide repeat SMALA_RS35895 dcb98998fe4a67fad9f3e06a93920c83 604 Gene3D G3DSA:3.30.413.10 409 602 2.3E-13 T 29-03-2018 SMALA_RS35895 dcb98998fe4a67fad9f3e06a93920c83 604 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 338 399 1.1E-10 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 SMALA_RS35895 dcb98998fe4a67fad9f3e06a93920c83 604 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 41 98 1.8E-9 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 SMALA_RS35895 dcb98998fe4a67fad9f3e06a93920c83 604 SUPERFAMILY SSF55124 268 405 3.27E-23 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 SMALA_RS35895 dcb98998fe4a67fad9f3e06a93920c83 604 SUPERFAMILY SSF55124 22 102 1.05E-19 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 SMALA_RS35895 dcb98998fe4a67fad9f3e06a93920c83 604 Gene3D G3DSA:3.90.480.10 37 220 1.1E-26 T 29-03-2018 SMALA_RS35895 dcb98998fe4a67fad9f3e06a93920c83 604 Gene3D G3DSA:3.90.480.10 255 407 4.6E-24 T 29-03-2018 SMALA_RS35895 dcb98998fe4a67fad9f3e06a93920c83 604 SUPERFAMILY SSF56014 108 210 1.16E-5 T 29-03-2018 SMALA_RS20965 678e09657517fc36d93c4b0a28d4ab36 1324 SUPERFAMILY SSF52540 74 602 5.71E-113 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS20965 678e09657517fc36d93c4b0a28d4ab36 1324 SMART SM00847 465 560 3.1E-36 T 29-03-2018 IPR007502 Helicase-associated domain GO:0004386 SMALA_RS20965 678e09657517fc36d93c4b0a28d4ab36 1324 SMART SM00490 305 405 4.0E-15 T 29-03-2018 IPR001650 Helicase, C-terminal SMALA_RS20965 678e09657517fc36d93c4b0a28d4ab36 1324 Pfam PF11898 Domain of unknown function (DUF3418) 729 1320 3.6E-234 T 29-03-2018 IPR024590 RNA helicase HrpA, C-terminal SMALA_RS20965 678e09657517fc36d93c4b0a28d4ab36 1324 Pfam PF04408 Helicase associated domain (HA2) 468 558 5.3E-18 T 29-03-2018 IPR007502 Helicase-associated domain GO:0004386 SMALA_RS20965 678e09657517fc36d93c4b0a28d4ab36 1324 Pfam PF00271 Helicase conserved C-terminal domain 287 404 1.7E-10 T 29-03-2018 IPR001650 Helicase, C-terminal SMALA_RS20965 678e09657517fc36d93c4b0a28d4ab36 1324 SMART SM00487 72 259 3.2E-29 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain SMALA_RS20965 678e09657517fc36d93c4b0a28d4ab36 1324 Gene3D G3DSA:3.40.50.300 76 235 5.2E-31 T 29-03-2018 SMALA_RS20965 678e09657517fc36d93c4b0a28d4ab36 1324 Gene3D G3DSA:3.40.50.300 253 425 1.8E-47 T 29-03-2018 SMALA_RS20965 678e09657517fc36d93c4b0a28d4ab36 1324 TIGRFAM TIGR01967 DEAH_box_HrpA: RNA helicase HrpA 13 1320 0.0 T 29-03-2018 IPR010222 RNA helicase HrpA GO:0004004 SMALA_RS20965 678e09657517fc36d93c4b0a28d4ab36 1324 SMART SM00382 92 385 2.5E-5 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS20965 678e09657517fc36d93c4b0a28d4ab36 1324 Pfam PF00270 DEAD/DEAH box helicase 87 233 3.7E-7 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 SMALA_RS20965 678e09657517fc36d93c4b0a28d4ab36 1324 Pfam PF07717 Oligonucleotide/oligosaccharide-binding (OB)-fold 623 715 3.9E-18 T 29-03-2018 IPR011709 Domain of unknown function DUF1605 SMALA_RS27785 2d54fd927f04e369d6cb261c747c47d6 543 SUPERFAMILY SSF53720 8 528 1.83E-124 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMALA_RS27785 2d54fd927f04e369d6cb261c747c47d6 543 Gene3D G3DSA:3.40.309.10 312 506 6.1E-45 T 29-03-2018 SMALA_RS27785 2d54fd927f04e369d6cb261c747c47d6 543 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 321 332 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 SMALA_RS27785 2d54fd927f04e369d6cb261c747c47d6 543 Pfam PF00171 Aldehyde dehydrogenase family 54 527 1.3E-103 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS27785 2d54fd927f04e369d6cb261c747c47d6 543 TIGRFAM TIGR01236 D1pyr5carbox1: 1-pyrroline-5-carboxylate dehydrogenase 12 542 2.0E-244 T 29-03-2018 IPR005931 Delta-1-pyrroline-5-carboxylate dehydrogenase GO:0003842|GO:0010133 KEGG: 00250+1.2.1.88|KEGG: 00330+1.2.1.88|MetaCyc: PWY-6853|Reactome: R-HSA-389661|Reactome: R-HSA-70688 SMALA_RS27785 2d54fd927f04e369d6cb261c747c47d6 543 Gene3D G3DSA:3.40.605.10 37 311 1.6E-69 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS38005 bb73d1bafeeebfa6555882b09828d4e6 352 Gene3D G3DSA:3.40.50.300 22 335 3.9E-79 T 29-03-2018 SMALA_RS38005 bb73d1bafeeebfa6555882b09828d4e6 352 SUPERFAMILY SSF52540 24 268 1.81E-76 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS38005 bb73d1bafeeebfa6555882b09828d4e6 352 Pfam PF00005 ABC transporter 44 197 7.9E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS38005 bb73d1bafeeebfa6555882b09828d4e6 352 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 249 316 7.3E-17 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMALA_RS38005 bb73d1bafeeebfa6555882b09828d4e6 352 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 247 324 2.1E-22 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMALA_RS38005 bb73d1bafeeebfa6555882b09828d4e6 352 SMART SM00382 53 247 1.9E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS38005 bb73d1bafeeebfa6555882b09828d4e6 352 ProSitePatterns PS00211 ABC transporters family signature. 170 184 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS23670 7ba00efeb1a0f9be26ad6e0a1e8a842b 334 SUPERFAMILY SSF88659 233 327 1.38E-22 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS23670 7ba00efeb1a0f9be26ad6e0a1e8a842b 334 SUPERFAMILY SSF88946 32 172 3.36E-48 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS23670 7ba00efeb1a0f9be26ad6e0a1e8a842b 334 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 295 321 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS23670 7ba00efeb1a0f9be26ad6e0a1e8a842b 334 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 99 324 2.7E-32 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS23670 7ba00efeb1a0f9be26ad6e0a1e8a842b 334 Gene3D G3DSA:1.10.10.10 172 222 7.9E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS23670 7ba00efeb1a0f9be26ad6e0a1e8a842b 334 Pfam PF00140 Sigma-70 factor, region 1.2 34 67 7.8E-11 T 29-03-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS23670 7ba00efeb1a0f9be26ad6e0a1e8a842b 334 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 126 139 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS23670 7ba00efeb1a0f9be26ad6e0a1e8a842b 334 PRINTS PR00046 Major sigma-70 factor signature 274 286 1.5E-24 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS23670 7ba00efeb1a0f9be26ad6e0a1e8a842b 334 PRINTS PR00046 Major sigma-70 factor signature 295 310 1.5E-24 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS23670 7ba00efeb1a0f9be26ad6e0a1e8a842b 334 PRINTS PR00046 Major sigma-70 factor signature 150 158 1.5E-24 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS23670 7ba00efeb1a0f9be26ad6e0a1e8a842b 334 PRINTS PR00046 Major sigma-70 factor signature 310 321 1.5E-24 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS23670 7ba00efeb1a0f9be26ad6e0a1e8a842b 334 PRINTS PR00046 Major sigma-70 factor signature 126 139 1.5E-24 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS23670 7ba00efeb1a0f9be26ad6e0a1e8a842b 334 Gene3D G3DSA:1.10.601.10 6 171 1.8E-59 T 29-03-2018 SMALA_RS23670 7ba00efeb1a0f9be26ad6e0a1e8a842b 334 SUPERFAMILY SSF88659 175 248 1.35E-16 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS23670 7ba00efeb1a0f9be26ad6e0a1e8a842b 334 Pfam PF04545 Sigma-70, region 4 271 323 5.7E-14 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS23670 7ba00efeb1a0f9be26ad6e0a1e8a842b 334 Pfam PF04542 Sigma-70 region 2 102 172 7.6E-21 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS23670 7ba00efeb1a0f9be26ad6e0a1e8a842b 334 Pfam PF04539 Sigma-70 region 3 181 257 2.1E-24 T 29-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS23670 7ba00efeb1a0f9be26ad6e0a1e8a842b 334 Gene3D G3DSA:1.10.10.10 264 330 3.4E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS37945 3ed067757135b61895c864cbe58bfac6 716 Gene3D G3DSA:3.30.365.10 165 270 3.5E-33 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMALA_RS37945 3ed067757135b61895c864cbe58bfac6 716 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 28 138 2.3E-22 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMALA_RS37945 3ed067757135b61895c864cbe58bfac6 716 Gene3D G3DSA:3.30.365.10 271 451 1.1E-31 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMALA_RS37945 3ed067757135b61895c864cbe58bfac6 716 SUPERFAMILY SSF56003 160 705 9.16E-151 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMALA_RS37945 3ed067757135b61895c864cbe58bfac6 716 Gene3D G3DSA:3.30.365.10 452 536 8.0E-18 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMALA_RS37945 3ed067757135b61895c864cbe58bfac6 716 SMART SM01008 28 139 2.0E-39 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMALA_RS37945 3ed067757135b61895c864cbe58bfac6 716 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 164 647 3.9E-103 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMALA_RS37945 3ed067757135b61895c864cbe58bfac6 716 SUPERFAMILY SSF54665 11 140 9.68E-36 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMALA_RS37945 3ed067757135b61895c864cbe58bfac6 716 Gene3D G3DSA:3.30.365.10 543 711 1.4E-42 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMALA_RS37945 3ed067757135b61895c864cbe58bfac6 716 Gene3D G3DSA:3.90.1170.50 3 138 1.3E-33 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMALA_RS38300 920b5fd61f3851c0ad13d22e624a8fcf 261 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 72 257 1.0E-19 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS38300 920b5fd61f3851c0ad13d22e624a8fcf 261 Gene3D G3DSA:1.10.3720.10 47 259 1.2E-41 T 29-03-2018 SMALA_RS38300 920b5fd61f3851c0ad13d22e624a8fcf 261 SUPERFAMILY SSF161098 53 244 8.76E-40 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS38300 920b5fd61f3851c0ad13d22e624a8fcf 261 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 53 149 5.0E-20 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 SMALA_RS23435 c6c80797c7364abf0c4e83f69dd9204f 247 Pfam PF12833 Helix-turn-helix domain 163 238 1.4E-21 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS23435 c6c80797c7364abf0c4e83f69dd9204f 247 Gene3D G3DSA:1.10.10.60 144 192 2.9E-12 T 29-03-2018 SMALA_RS23435 c6c80797c7364abf0c4e83f69dd9204f 247 SUPERFAMILY SSF51182 9 160 3.65E-10 T 29-03-2018 IPR011051 RmlC-like cupin domain SMALA_RS23435 c6c80797c7364abf0c4e83f69dd9204f 247 SUPERFAMILY SSF46689 191 241 2.02E-9 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS23435 c6c80797c7364abf0c4e83f69dd9204f 247 SMART SM00342 155 237 5.9E-23 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS23435 c6c80797c7364abf0c4e83f69dd9204f 247 Gene3D G3DSA:2.60.120.10 7 143 9.4E-7 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SMALA_RS23435 c6c80797c7364abf0c4e83f69dd9204f 247 Gene3D G3DSA:1.10.10.60 193 246 2.6E-10 T 29-03-2018 SMALA_RS14125 d4de737523115f71118b3dc4035ce74d 446 Pfam PF07730 Histidine kinase 227 292 2.6E-20 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMALA_RS14125 d4de737523115f71118b3dc4035ce74d 446 Gene3D G3DSA:3.30.565.10 302 436 2.7E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS14125 d4de737523115f71118b3dc4035ce74d 446 SUPERFAMILY SSF55874 312 428 3.01E-13 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS33195 6fe3fec3ec7ab8be9dfb4b6735571c6e 120 Gene3D G3DSA:1.10.10.10 1 110 4.6E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS33195 6fe3fec3ec7ab8be9dfb4b6735571c6e 120 Pfam PF01022 Bacterial regulatory protein, arsR family 17 61 1.6E-15 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS33195 6fe3fec3ec7ab8be9dfb4b6735571c6e 120 SUPERFAMILY SSF46785 6 102 6.67E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS33195 6fe3fec3ec7ab8be9dfb4b6735571c6e 120 SMART SM00418 9 90 2.8E-20 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS33195 6fe3fec3ec7ab8be9dfb4b6735571c6e 120 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 43 58 1.6E-11 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS33195 6fe3fec3ec7ab8be9dfb4b6735571c6e 120 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 58 73 1.6E-11 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS33195 6fe3fec3ec7ab8be9dfb4b6735571c6e 120 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 11 26 1.6E-11 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS07305 b4e2d24902254c358eda15ed1ced0de8 233 SUPERFAMILY SSF56784 19 219 7.73E-45 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS07305 b4e2d24902254c358eda15ed1ced0de8 233 Pfam PF13419 Haloacid dehalogenase-like hydrolase 21 199 2.2E-25 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS07305 b4e2d24902254c358eda15ed1ced0de8 233 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 18 29 2.4E-7 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMALA_RS07305 b4e2d24902254c358eda15ed1ced0de8 233 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 161 181 2.4E-7 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMALA_RS07305 b4e2d24902254c358eda15ed1ced0de8 233 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 113 126 2.4E-7 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMALA_RS07305 b4e2d24902254c358eda15ed1ced0de8 233 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 143 159 2.4E-7 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMALA_RS07305 b4e2d24902254c358eda15ed1ced0de8 233 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 91 199 4.0E-14 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMALA_RS07305 b4e2d24902254c358eda15ed1ced0de8 233 Gene3D G3DSA:3.40.50.1000 90 227 1.1E-23 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS07305 b4e2d24902254c358eda15ed1ced0de8 233 Gene3D G3DSA:1.10.150.240 31 89 7.7E-16 T 29-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 SMALA_RS01215 4c31c61af7fc03d0bd9a93891fd719d8 611 Gene3D G3DSA:1.50.10.10 205 569 1.6E-104 T 29-03-2018 SMALA_RS01215 4c31c61af7fc03d0bd9a93891fd719d8 611 SUPERFAMILY SSF48208 210 610 1.29E-108 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 SMALA_RS01215 4c31c61af7fc03d0bd9a93891fd719d8 611 Pfam PF00723 Glycosyl hydrolases family 15 238 555 4.9E-54 T 29-03-2018 IPR011613 Glycoside hydrolase family 15/Phosphorylase b kinase regulatory chain family Reactome: R-HSA-70221 SMALA_RS14515 ebac67f832d8b0b15a5232869bf922c6 316 Gene3D G3DSA:3.40.50.880 1 226 1.7E-56 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS14515 ebac67f832d8b0b15a5232869bf922c6 316 Pfam PF12833 Helix-turn-helix domain 231 309 1.5E-24 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS14515 ebac67f832d8b0b15a5232869bf922c6 316 SMART SM00342 225 308 3.5E-32 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS14515 ebac67f832d8b0b15a5232869bf922c6 316 SUPERFAMILY SSF46689 212 259 4.72E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS14515 ebac67f832d8b0b15a5232869bf922c6 316 Gene3D G3DSA:1.10.10.60 268 315 2.5E-14 T 29-03-2018 SMALA_RS14515 ebac67f832d8b0b15a5232869bf922c6 316 SUPERFAMILY SSF52317 1 188 8.07E-43 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS14515 ebac67f832d8b0b15a5232869bf922c6 316 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 262 304 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 SMALA_RS14515 ebac67f832d8b0b15a5232869bf922c6 316 SUPERFAMILY SSF46689 262 312 1.36E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS14515 ebac67f832d8b0b15a5232869bf922c6 316 Pfam PF01965 DJ-1/PfpI family 3 169 4.8E-14 T 29-03-2018 IPR002818 DJ-1/PfpI SMALA_RS14515 ebac67f832d8b0b15a5232869bf922c6 316 Gene3D G3DSA:1.10.10.60 227 267 2.9E-15 T 29-03-2018 SMALA_RS08275 56ecef09e8d0c688d2b97a48356f9911 447 Hamap MF_00334 Homogentisate 1,2-dioxygenase [hmgA]. 18 447 69.867 T 29-03-2018 IPR022950 Homogentisate 1,2-dioxygenase, bacterial GO:0004411|GO:0006559|GO:0006572|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5 SMALA_RS08275 56ecef09e8d0c688d2b97a48356f9911 447 SUPERFAMILY SSF51182 17 447 1.23E-161 T 29-03-2018 IPR011051 RmlC-like cupin domain SMALA_RS08275 56ecef09e8d0c688d2b97a48356f9911 447 TIGRFAM TIGR01015 hmgA: homogentisate 1,2-dioxygenase 17 445 2.0E-212 T 29-03-2018 IPR005708 Homogentisate 1,2-dioxygenase GO:0004411|GO:0006559|GO:0006570|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5|Reactome: R-HSA-71182 SMALA_RS08275 56ecef09e8d0c688d2b97a48356f9911 447 Pfam PF04209 homogentisate 1,2-dioxygenase 19 445 5.3E-205 T 29-03-2018 IPR005708 Homogentisate 1,2-dioxygenase GO:0004411|GO:0006559|GO:0006570|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5|Reactome: R-HSA-71182 SMALA_RS08275 56ecef09e8d0c688d2b97a48356f9911 447 Gene3D G3DSA:2.60.120.10 209 262 7.9E-11 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SMALA_RS08275 56ecef09e8d0c688d2b97a48356f9911 447 Gene3D G3DSA:2.60.120.10 290 415 5.1E-50 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SMALA_RS01800 537baaa104c7b69e0229542c5bc7b4d1 64 Gene3D G3DSA:3.30.70.20 1 64 1.1E-9 T 29-03-2018 SMALA_RS01800 537baaa104c7b69e0229542c5bc7b4d1 64 SUPERFAMILY SSF54862 2 62 9.21E-12 T 29-03-2018 SMALA_RS01800 537baaa104c7b69e0229542c5bc7b4d1 64 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 5 62 1.3E-11 T 29-03-2018 SMALA_RS01800 537baaa104c7b69e0229542c5bc7b4d1 64 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 3.3E-5 T 29-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 SMALA_RS01800 537baaa104c7b69e0229542c5bc7b4d1 64 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 3.3E-5 T 29-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 SMALA_RS01800 537baaa104c7b69e0229542c5bc7b4d1 64 PRINTS PR00352 3Fe-4S ferredoxin signature 48 60 3.3E-5 T 29-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 SMALA_RS14770 1c609de33868880c87eef8b12ab8602d 260 Gene3D G3DSA:3.20.20.30 1 251 4.3E-43 T 29-03-2018 SMALA_RS14770 1c609de33868880c87eef8b12ab8602d 260 Pfam PF00296 Luciferase-like monooxygenase 8 215 3.2E-30 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS14770 1c609de33868880c87eef8b12ab8602d 260 SUPERFAMILY SSF51679 3 247 9.57E-44 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS14770 1c609de33868880c87eef8b12ab8602d 260 TIGRFAM TIGR03856 F420_MSMEG_2906: probable F420-dependent oxidoreductase, MSMEG_2906 family 3 255 5.7E-83 T 29-03-2018 IPR022480 F420-dependent oxidoreductase, MSMEG2906 SMALA_RS34095 4fa7762576e808c24767aa879990ae41 439 SUPERFAMILY SSF52777 226 422 3.67E-5 T 29-03-2018 SMALA_RS34095 4fa7762576e808c24767aa879990ae41 439 Pfam PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain 89 242 8.1E-6 T 29-03-2018 IPR004255 O-acyltransferase, WSD1, N-terminal GO:0004144|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 SMALA_RS34095 4fa7762576e808c24767aa879990ae41 439 Pfam PF06974 Protein of unknown function (DUF1298) 289 401 1.5E-7 T 29-03-2018 IPR009721 O-acyltransferase WSD1, C-terminal GO:0004144 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 SMALA_RS23870 e2cb7beeaf377197a0dacb28763c552c 256 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS23870 e2cb7beeaf377197a0dacb28763c552c 256 Gene3D G3DSA:3.40.50.300 6 242 3.9E-66 T 29-03-2018 SMALA_RS23870 e2cb7beeaf377197a0dacb28763c552c 256 SMART SM00382 36 225 3.2E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS23870 e2cb7beeaf377197a0dacb28763c552c 256 TIGRFAM TIGR01166 cbiO: cobalt ABC transporter, ATP-binding protein 20 201 5.2E-65 T 29-03-2018 IPR005876 Cobalt transport protein ATP-binding subunit GO:0006824 SMALA_RS23870 e2cb7beeaf377197a0dacb28763c552c 256 SUPERFAMILY SSF52540 9 233 1.81E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS23870 e2cb7beeaf377197a0dacb28763c552c 256 Pfam PF00005 ABC transporter 29 172 2.2E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS00140 8fe7978c64f32ca3626fe0e82592fa04 746 Pfam PF01381 Helix-turn-helix 30 74 5.1E-9 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS00140 8fe7978c64f32ca3626fe0e82592fa04 746 SUPERFAMILY SSF47413 30 76 2.6E-8 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS00140 8fe7978c64f32ca3626fe0e82592fa04 746 Gene3D G3DSA:1.10.260.40 30 112 6.0E-12 T 29-03-2018 SMALA_RS00140 8fe7978c64f32ca3626fe0e82592fa04 746 SMART SM00530 28 82 7.3E-5 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS31985 afb07f0d53fa9806dfb64b9d7bc2ab28 660 Gene3D G3DSA:2.60.120.260 389 622 2.9E-41 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS31985 afb07f0d53fa9806dfb64b9d7bc2ab28 660 SUPERFAMILY SSF49785 429 623 1.08E-32 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS31985 afb07f0d53fa9806dfb64b9d7bc2ab28 660 Gene3D G3DSA:3.40.50.1820 36 388 7.2E-36 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS31985 afb07f0d53fa9806dfb64b9d7bc2ab28 660 SUPERFAMILY SSF53474 46 383 1.03E-68 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS31985 afb07f0d53fa9806dfb64b9d7bc2ab28 660 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 72 345 8.1E-57 T 29-03-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 SMALA_RS31985 afb07f0d53fa9806dfb64b9d7bc2ab28 660 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 372 617 2.9E-43 T 29-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 SMALA_RS31985 afb07f0d53fa9806dfb64b9d7bc2ab28 660 SMART SM00939 360 627 9.8E-48 T 29-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 SMALA_RS24760 da887d4cc7545b7d02844c58e7b46276 228 SUPERFAMILY SSF52540 8 224 1.0E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS24760 da887d4cc7545b7d02844c58e7b46276 228 SMART SM00382 32 220 4.6E-18 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS24760 da887d4cc7545b7d02844c58e7b46276 228 Pfam PF00005 ABC transporter 23 171 5.6E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS24760 da887d4cc7545b7d02844c58e7b46276 228 Gene3D G3DSA:3.40.50.300 4 226 4.9E-60 T 29-03-2018 SMALA_RS39460 712fdbfe1bd7514d91a20647d4e50f7c 143 Gene3D G3DSA:3.40.1400.10 1 142 9.1E-50 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 SMALA_RS39460 712fdbfe1bd7514d91a20647d4e50f7c 143 PIRSF PIRSF005384 1 142 3.2E-44 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 SMALA_RS39460 712fdbfe1bd7514d91a20647d4e50f7c 143 Pfam PF02502 Ribose/Galactose Isomerase 1 136 2.0E-42 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 SMALA_RS39460 712fdbfe1bd7514d91a20647d4e50f7c 143 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 1 141 1.1E-41 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 SMALA_RS39460 712fdbfe1bd7514d91a20647d4e50f7c 143 SUPERFAMILY SSF89623 1 140 2.88E-43 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 SMALA_RS32530 d2b81619a6e4a359794d46d25084a99b 390 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 64 380 4.3E-44 T 29-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 SMALA_RS32530 d2b81619a6e4a359794d46d25084a99b 390 SUPERFAMILY SSF51695 58 381 2.38E-79 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 SMALA_RS32530 d2b81619a6e4a359794d46d25084a99b 390 Gene3D G3DSA:3.20.20.190 46 389 6.1E-67 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 SMALA_RS06645 1c09fe995cfa296c8c26f61fb9e4ce81 328 Pfam PF04909 Amidohydrolase 35 322 1.7E-36 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 SMALA_RS06645 1c09fe995cfa296c8c26f61fb9e4ce81 328 SUPERFAMILY SSF51556 34 324 1.19E-69 T 29-03-2018 IPR032466 Metal-dependent hydrolase SMALA_RS06645 1c09fe995cfa296c8c26f61fb9e4ce81 328 Gene3D G3DSA:3.20.20.140 6 325 1.3E-54 T 29-03-2018 SMALA_RS40820 6b78046267f9ba01c7f5f978c5c325ba 305 SUPERFAMILY SSF52317 61 305 6.18E-65 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS40820 6b78046267f9ba01c7f5f978c5c325ba 305 Pfam PF07090 Putative glutamine amidotransferase 60 304 1.5E-91 T 29-03-2018 IPR010768 Putative glutamine amidotransferase SMALA_RS40820 6b78046267f9ba01c7f5f978c5c325ba 305 Gene3D G3DSA:3.40.50.880 51 305 1.7E-50 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS02265 d16e776cfc5d9ae33ac671efe52d4f23 388 SUPERFAMILY SSF53383 11 385 6.46E-100 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS02265 d16e776cfc5d9ae33ac671efe52d4f23 388 Gene3D G3DSA:3.40.640.10 18 243 2.6E-46 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS02265 d16e776cfc5d9ae33ac671efe52d4f23 388 PIRSF PIRSF000390 6 387 2.3E-108 T 29-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase SMALA_RS02265 d16e776cfc5d9ae33ac671efe52d4f23 388 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 18 380 1.9E-113 T 29-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase SMALA_RS02265 d16e776cfc5d9ae33ac671efe52d4f23 388 Gene3D G3DSA:3.90.1150.10 244 388 2.1E-20 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS09320 d73c5f48fefcad36f1fd7ce3e83e7950 390 SUPERFAMILY SSF55347 136 292 4.8E-13 T 29-03-2018 SMALA_RS09320 d73c5f48fefcad36f1fd7ce3e83e7950 390 SUPERFAMILY SSF51735 6 154 2.96E-27 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS09320 d73c5f48fefcad36f1fd7ce3e83e7950 390 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 8 126 1.8E-12 T 29-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 SMALA_RS09320 d73c5f48fefcad36f1fd7ce3e83e7950 390 Gene3D G3DSA:3.40.50.720 3 145 1.5E-24 T 29-03-2018 SMALA_RS09320 d73c5f48fefcad36f1fd7ce3e83e7950 390 Gene3D G3DSA:3.30.360.10 146 329 1.5E-20 T 29-03-2018 SMALA_RS22610 f91ca054a6d16bd18e0a683f12258239 132 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 132 30.943 T 29-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMALA_RS22610 f91ca054a6d16bd18e0a683f12258239 132 Pfam PF00410 Ribosomal protein S8 5 132 3.5E-50 T 29-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMALA_RS22610 f91ca054a6d16bd18e0a683f12258239 132 Gene3D G3DSA:3.30.1370.30 1 66 2.4E-24 T 29-03-2018 SMALA_RS22610 f91ca054a6d16bd18e0a683f12258239 132 SUPERFAMILY SSF56047 3 132 1.31E-44 T 29-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMALA_RS22610 f91ca054a6d16bd18e0a683f12258239 132 Gene3D G3DSA:3.30.1490.10 76 131 4.9E-20 T 29-03-2018 SMALA_RS20125 a1e4813913b85437d969e3c0d89fffb3 815 Gene3D G3DSA:2.60.40.10 28 150 8.9E-5 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS20125 a1e4813913b85437d969e3c0d89fffb3 815 Pfam PF17210 SdrD B-like domain 580 719 1.2E-13 T 29-03-2018 IPR033764 SD-repeat containing protein, B domain SMALA_RS20125 a1e4813913b85437d969e3c0d89fffb3 815 Gene3D G3DSA:2.60.40.10 577 729 1.2E-17 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS20125 a1e4813913b85437d969e3c0d89fffb3 815 SUPERFAMILY SSF63829 372 385 6.34E-6 T 29-03-2018 SMALA_RS20125 a1e4813913b85437d969e3c0d89fffb3 815 SUPERFAMILY SSF63829 206 330 6.34E-6 T 29-03-2018 SMALA_RS20125 a1e4813913b85437d969e3c0d89fffb3 815 SUPERFAMILY SSF117074 568 663 5.62E-13 T 29-03-2018 SMALA_RS25220 2e48a1988ece985a0fc2ae6c54748bc4 228 Gene3D G3DSA:3.90.230.10 2 194 2.1E-18 T 29-03-2018 SMALA_RS25220 2e48a1988ece985a0fc2ae6c54748bc4 228 Pfam PF00557 Metallopeptidase family M24 10 173 5.4E-16 T 29-03-2018 IPR000994 Peptidase M24 SMALA_RS25220 2e48a1988ece985a0fc2ae6c54748bc4 228 SUPERFAMILY SSF55920 9 175 3.14E-20 T 29-03-2018 IPR000994 Peptidase M24 SMALA_RS28955 d578fa0137bc54ec351cf57215b99f5a 666 Gene3D G3DSA:3.40.50.300 23 427 3.1E-27 T 29-03-2018 SMALA_RS28955 d578fa0137bc54ec351cf57215b99f5a 666 Pfam PF13307 Helicase C-terminal domain 481 639 3.0E-26 T 29-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 SMALA_RS28955 d578fa0137bc54ec351cf57215b99f5a 666 SMART SM00491 498 627 3.7E-41 T 29-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 SMALA_RS28955 d578fa0137bc54ec351cf57215b99f5a 666 SUPERFAMILY SSF52540 455 610 2.05E-19 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS28955 d578fa0137bc54ec351cf57215b99f5a 666 SUPERFAMILY SSF52540 194 265 2.05E-19 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS28955 d578fa0137bc54ec351cf57215b99f5a 666 SUPERFAMILY SSF52540 397 411 2.05E-19 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS28955 d578fa0137bc54ec351cf57215b99f5a 666 SUPERFAMILY SSF52540 39 88 2.05E-19 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS28955 d578fa0137bc54ec351cf57215b99f5a 666 Gene3D G3DSA:3.40.50.300 463 666 1.8E-9 T 29-03-2018 SMALA_RS28955 d578fa0137bc54ec351cf57215b99f5a 666 SMART SM00487 20 293 2.3E-4 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain SMALA_RS20030 7fb77e95b02974200dc3efb1ae20d664 345 Gene3D G3DSA:1.10.510.10 176 287 3.6E-11 T 29-03-2018 SMALA_RS20030 7fb77e95b02974200dc3efb1ae20d664 345 Pfam PF01636 Phosphotransferase enzyme family 34 280 1.1E-26 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase SMALA_RS20030 7fb77e95b02974200dc3efb1ae20d664 345 SUPERFAMILY SSF56112 16 332 4.96E-40 T 29-03-2018 IPR011009 Protein kinase-like domain SMALA_RS20030 7fb77e95b02974200dc3efb1ae20d664 345 Gene3D G3DSA:3.30.200.20 10 113 1.3E-26 T 29-03-2018 SMALA_RS22245 e71271177fd6d682cc216ad7fe15cd0b 650 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 291 506 9.9E-51 T 29-03-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 SMALA_RS22245 e71271177fd6d682cc216ad7fe15cd0b 650 Gene3D G3DSA:3.40.50.920 545 650 4.5E-7 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMALA_RS22245 e71271177fd6d682cc216ad7fe15cd0b 650 SUPERFAMILY SSF53323 44 264 1.23E-17 T 29-03-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 SMALA_RS22245 e71271177fd6d682cc216ad7fe15cd0b 650 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 549 616 6.9E-7 T 29-03-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II SMALA_RS22245 e71271177fd6d682cc216ad7fe15cd0b 650 SUPERFAMILY SSF52922 548 648 3.66E-12 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMALA_RS22245 e71271177fd6d682cc216ad7fe15cd0b 650 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 50 238 6.6E-26 T 29-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 SMALA_RS22245 e71271177fd6d682cc216ad7fe15cd0b 650 Gene3D G3DSA:3.40.920.10 39 255 2.4E-41 T 29-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 SMALA_RS22245 e71271177fd6d682cc216ad7fe15cd0b 650 Gene3D G3DSA:3.40.50.970 263 534 1.0E-58 T 29-03-2018 SMALA_RS22245 e71271177fd6d682cc216ad7fe15cd0b 650 TIGRFAM TIGR03710 OAFO_sf: 2-oxoacid:acceptor oxidoreductase, alpha subunit 42 643 3.5E-195 T 29-03-2018 IPR022367 2-oxoacid:acceptor oxidoreductase, alpha subunit KEGG: 00020+1.2.7.3|KEGG: 00720+1.2.7.3|MetaCyc: PWY-5392|MetaCyc: PWY-6969 SMALA_RS22245 e71271177fd6d682cc216ad7fe15cd0b 650 SUPERFAMILY SSF52518 264 532 5.4E-60 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold SMALA_RS30260 6b2133312df4da931b6e24fadfbe753a 312 Hamap MF_00064 Sulfate adenylyltransferase subunit 2 [cysD]. 16 312 53.658 T 29-03-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 SMALA_RS30260 6b2133312df4da931b6e24fadfbe753a 312 SUPERFAMILY SSF52402 18 219 1.89E-62 T 29-03-2018 SMALA_RS30260 6b2133312df4da931b6e24fadfbe753a 312 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 42 266 4.8E-47 T 29-03-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 SMALA_RS30260 6b2133312df4da931b6e24fadfbe753a 312 Gene3D G3DSA:3.40.50.620 15 309 7.6E-39 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS30260 6b2133312df4da931b6e24fadfbe753a 312 PIRSF PIRSF002936 13 312 3.4E-137 T 29-03-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 SMALA_RS30260 6b2133312df4da931b6e24fadfbe753a 312 TIGRFAM TIGR02039 CysD: sulfate adenylyltransferase, small subunit 21 312 3.4E-139 T 29-03-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 SMALA_RS22210 4946ba1c8bc1902d501c8a54aab81f91 327 SMART SM00382 38 246 3.1E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS22210 4946ba1c8bc1902d501c8a54aab81f91 327 Pfam PF00005 ABC transporter 30 174 9.0E-26 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS22210 4946ba1c8bc1902d501c8a54aab81f91 327 Gene3D G3DSA:3.40.50.300 10 267 5.7E-62 T 29-03-2018 SMALA_RS22210 4946ba1c8bc1902d501c8a54aab81f91 327 SUPERFAMILY SSF52540 10 235 1.48E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS22210 4946ba1c8bc1902d501c8a54aab81f91 327 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS30630 be6b8e347d4fcb9b6c3ec481dacabe77 329 SUPERFAMILY SSF53822 46 319 2.67E-45 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SMALA_RS30630 be6b8e347d4fcb9b6c3ec481dacabe77 329 Gene3D G3DSA:3.40.50.2300 38 162 1.0E-20 T 29-03-2018 SMALA_RS30630 be6b8e347d4fcb9b6c3ec481dacabe77 329 Pfam PF13407 Periplasmic binding protein domain 48 290 3.3E-35 T 29-03-2018 IPR025997 Periplasmic binding protein SMALA_RS30630 be6b8e347d4fcb9b6c3ec481dacabe77 329 Gene3D G3DSA:3.40.50.2300 163 290 2.3E-12 T 29-03-2018 SMALA_RS19955 d7feff6e4d7e918585edc741be918c4c 505 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 14 192 1.6E-59 T 29-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 SMALA_RS19955 d7feff6e4d7e918585edc741be918c4c 505 Gene3D G3DSA:3.40.50.720 6 192 1.3E-51 T 29-03-2018 SMALA_RS19955 d7feff6e4d7e918585edc741be918c4c 505 SUPERFAMILY SSF51735 13 193 3.95E-54 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS19955 d7feff6e4d7e918585edc741be918c4c 505 Gene3D G3DSA:1.10.1040.10 193 296 5.9E-24 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMALA_RS19955 d7feff6e4d7e918585edc741be918c4c 505 SUPERFAMILY SSF48179 417 501 3.74E-14 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMALA_RS19955 d7feff6e4d7e918585edc741be918c4c 505 SUPERFAMILY SSF48179 193 300 1.02E-25 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMALA_RS19955 d7feff6e4d7e918585edc741be918c4c 505 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 194 290 4.9E-26 T 29-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 SMALA_RS19955 d7feff6e4d7e918585edc741be918c4c 505 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 418 496 8.7E-11 T 29-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 SMALA_RS19955 d7feff6e4d7e918585edc741be918c4c 505 Gene3D G3DSA:1.10.1040.10 420 504 1.3E-11 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMALA_RS19955 d7feff6e4d7e918585edc741be918c4c 505 Gene3D G3DSA:3.40.50.720 327 419 0.35 T 29-03-2018 SMALA_RS15010 d48d103c97f461874c6ebe3b8c1ff2cc 243 SUPERFAMILY SSF55666 156 240 1.05E-23 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 SMALA_RS15010 d48d103c97f461874c6ebe3b8c1ff2cc 243 Pfam PF01138 3' exoribonuclease family, domain 1 11 141 1.6E-22 T 29-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 SMALA_RS15010 d48d103c97f461874c6ebe3b8c1ff2cc 243 Hamap MF_00564 Ribonuclease PH [rph]. 2 240 47.263 T 29-03-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 SMALA_RS15010 d48d103c97f461874c6ebe3b8c1ff2cc 243 Pfam PF03725 3' exoribonuclease family, domain 2 162 225 3.8E-9 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 SMALA_RS15010 d48d103c97f461874c6ebe3b8c1ff2cc 243 SUPERFAMILY SSF54211 3 183 1.72E-45 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SMALA_RS15010 d48d103c97f461874c6ebe3b8c1ff2cc 243 Gene3D G3DSA:3.30.230.70 2 243 6.8E-61 T 29-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 SMALA_RS15010 d48d103c97f461874c6ebe3b8c1ff2cc 243 ProSitePatterns PS01277 Ribonuclease PH signature. 117 130 - T 29-03-2018 IPR018336 Ribonuclease PH, conserved site SMALA_RS15010 d48d103c97f461874c6ebe3b8c1ff2cc 243 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 3 239 1.5E-113 T 29-03-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 SMALA_RS06800 269e10e9a54255c3af555a0b70389107 331 Gene3D G3DSA:3.40.47.10 1 169 9.8E-37 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS06800 269e10e9a54255c3af555a0b70389107 331 Gene3D G3DSA:3.40.47.10 170 330 9.9E-37 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS06800 269e10e9a54255c3af555a0b70389107 331 SUPERFAMILY SSF53901 12 328 6.36E-62 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS06800 269e10e9a54255c3af555a0b70389107 331 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 11 330 56.068 T 29-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SMALA_RS06800 269e10e9a54255c3af555a0b70389107 331 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 240 328 2.4E-28 T 29-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SMALA_RS06800 269e10e9a54255c3af555a0b70389107 331 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 115 192 6.7E-25 T 29-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SMALA_RS06800 269e10e9a54255c3af555a0b70389107 331 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 12 329 5.0E-101 T 29-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SMALA_RS35760 6b06817f460b9ad6abdaa058e22905c6 234 Gene3D G3DSA:3.40.50.2300 2 138 3.2E-39 T 29-03-2018 SMALA_RS35760 6b06817f460b9ad6abdaa058e22905c6 234 Pfam PF00072 Response regulator receiver domain 5 114 1.0E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS35760 6b06817f460b9ad6abdaa058e22905c6 234 Gene3D G3DSA:1.10.10.10 139 234 9.4E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS35760 6b06817f460b9ad6abdaa058e22905c6 234 Pfam PF00486 Transcriptional regulatory protein, C terminal 156 231 1.3E-22 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS35760 6b06817f460b9ad6abdaa058e22905c6 234 SUPERFAMILY SSF46894 135 232 1.73E-27 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS35760 6b06817f460b9ad6abdaa058e22905c6 234 SUPERFAMILY SSF52172 4 126 2.28E-42 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS35760 6b06817f460b9ad6abdaa058e22905c6 234 SMART SM00448 3 114 1.9E-42 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS35760 6b06817f460b9ad6abdaa058e22905c6 234 SMART SM00862 156 231 2.2E-24 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS12680 affbf93d00650eb966c5d2383b899121 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 149 194 3.5E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS12680 affbf93d00650eb966c5d2383b899121 218 SUPERFAMILY SSF52172 2 139 1.57E-17 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS12680 affbf93d00650eb966c5d2383b899121 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 164 9.0E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS12680 affbf93d00650eb966c5d2383b899121 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 192 9.0E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS12680 affbf93d00650eb966c5d2383b899121 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 180 9.0E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS12680 affbf93d00650eb966c5d2383b899121 218 SMART SM00421 147 210 3.5E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS12680 affbf93d00650eb966c5d2383b899121 218 Gene3D G3DSA:3.40.50.2300 1 131 7.2E-24 T 29-03-2018 SMALA_RS12680 affbf93d00650eb966c5d2383b899121 218 SUPERFAMILY SSF46894 135 194 1.39E-13 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS12680 affbf93d00650eb966c5d2383b899121 218 Gene3D G3DSA:1.10.10.10 132 214 8.3E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS12680 affbf93d00650eb966c5d2383b899121 218 Pfam PF00072 Response regulator receiver domain 4 108 3.9E-15 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS12680 affbf93d00650eb966c5d2383b899121 218 SMART SM00448 1 120 1.7E-5 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS35250 e4409e862900e3dfac65663bd2ac0f45 301 PRINTS PR01438 Universal stress protein signature 99 111 2.0E-11 T 29-03-2018 IPR006015 Universal stress protein A SMALA_RS35250 e4409e862900e3dfac65663bd2ac0f45 301 PRINTS PR01438 Universal stress protein signature 2 20 2.0E-11 T 29-03-2018 IPR006015 Universal stress protein A SMALA_RS35250 e4409e862900e3dfac65663bd2ac0f45 301 PRINTS PR01438 Universal stress protein signature 117 139 2.0E-11 T 29-03-2018 IPR006015 Universal stress protein A SMALA_RS35250 e4409e862900e3dfac65663bd2ac0f45 301 Gene3D G3DSA:3.40.50.620 4 141 4.9E-28 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS35250 e4409e862900e3dfac65663bd2ac0f45 301 Pfam PF00582 Universal stress protein family 151 292 7.1E-13 T 29-03-2018 IPR006016 UspA GO:0006950 SMALA_RS35250 e4409e862900e3dfac65663bd2ac0f45 301 Pfam PF00582 Universal stress protein family 5 139 6.0E-22 T 29-03-2018 IPR006016 UspA GO:0006950 SMALA_RS35250 e4409e862900e3dfac65663bd2ac0f45 301 SUPERFAMILY SSF52402 5 142 1.59E-26 T 29-03-2018 SMALA_RS35250 e4409e862900e3dfac65663bd2ac0f45 301 Gene3D G3DSA:3.40.50.620 142 301 2.9E-23 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS35250 e4409e862900e3dfac65663bd2ac0f45 301 SUPERFAMILY SSF52402 166 295 3.1E-17 T 29-03-2018 SMALA_RS00255 905f62106d5efe482735778ff313da72 366 Pfam PF06224 Winged helix DNA-binding domain 31 350 4.9E-69 T 29-03-2018 IPR009351 Protein of unknown function DUF1006 SMALA_RS17745 fdc9072b79a8d7b9f370b79dff13bb71 120 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 67 82 1.2E-9 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS17745 fdc9072b79a8d7b9f370b79dff13bb71 120 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 21 36 1.2E-9 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS17745 fdc9072b79a8d7b9f370b79dff13bb71 120 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 52 67 1.2E-9 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS17745 fdc9072b79a8d7b9f370b79dff13bb71 120 SMART SM00418 19 96 4.6E-13 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS17745 fdc9072b79a8d7b9f370b79dff13bb71 120 SUPERFAMILY SSF46785 7 95 1.91E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS17745 fdc9072b79a8d7b9f370b79dff13bb71 120 Pfam PF12840 Helix-turn-helix domain 22 75 9.4E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS17745 fdc9072b79a8d7b9f370b79dff13bb71 120 Gene3D G3DSA:1.10.10.10 1 108 1.6E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS26150 24eb5a6f65f6a72cc5debd3ebc2a7c06 186 SUPERFAMILY SSF46689 4 73 1.05E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS26150 24eb5a6f65f6a72cc5debd3ebc2a7c06 186 Gene3D G3DSA:1.10.10.60 43 164 2.4E-12 T 29-03-2018 SMALA_RS26150 24eb5a6f65f6a72cc5debd3ebc2a7c06 186 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 52 1.7E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS26150 24eb5a6f65f6a72cc5debd3ebc2a7c06 186 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 8 21 1.7E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS26150 24eb5a6f65f6a72cc5debd3ebc2a7c06 186 Pfam PF00440 Bacterial regulatory proteins, tetR family 8 54 9.3E-13 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS26150 24eb5a6f65f6a72cc5debd3ebc2a7c06 186 Gene3D G3DSA:1.10.10.60 2 42 7.8E-16 T 29-03-2018 SMALA_RS26870 d249f039ea0979f6e780d2b44150b06e 219 SUPERFAMILY SSF52788 182 210 3.14E-22 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily SMALA_RS26870 d249f039ea0979f6e780d2b44150b06e 219 SUPERFAMILY SSF52788 20 143 3.14E-22 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily SMALA_RS26870 d249f039ea0979f6e780d2b44150b06e 219 SMART SM00226 21 211 5.1E-6 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily SMALA_RS26870 d249f039ea0979f6e780d2b44150b06e 219 Gene3D G3DSA:3.40.50.2300 15 216 8.2E-34 T 29-03-2018 SMALA_RS26870 d249f039ea0979f6e780d2b44150b06e 219 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 23 152 7.4E-15 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily SMALA_RS00710 3398410ceda013595944b5da197011fe 281 SUPERFAMILY SSF141571 65 101 1.86E-22 T 29-03-2018 SMALA_RS00710 3398410ceda013595944b5da197011fe 281 SUPERFAMILY SSF141571 180 277 1.86E-22 T 29-03-2018 SMALA_RS00710 3398410ceda013595944b5da197011fe 281 Gene3D G3DSA:2.160.20.80 56 272 1.1E-28 T 29-03-2018 SMALA_RS00710 3398410ceda013595944b5da197011fe 281 Pfam PF00805 Pentapeptide repeats (8 copies) 196 230 2.6E-11 T 29-03-2018 IPR001646 Pentapeptide repeat SMALA_RS08030 0420235e14e78850eb977f101e55f6c1 269 SUPERFAMILY SSF51735 1 233 1.35E-35 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS08030 0420235e14e78850eb977f101e55f6c1 269 Gene3D G3DSA:3.40.50.720 84 265 8.5E-13 T 29-03-2018 SMALA_RS08030 0420235e14e78850eb977f101e55f6c1 269 Pfam PF13460 NAD(P)H-binding 4 162 1.3E-6 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS08030 0420235e14e78850eb977f101e55f6c1 269 Gene3D G3DSA:3.40.50.720 1 83 2.6E-7 T 29-03-2018 SMALA_RS01760 c848c08913627a97c2022c412282bf55 336 SUPERFAMILY SSF53474 84 334 4.79E-57 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS01760 c848c08913627a97c2022c412282bf55 336 Pfam PF07859 alpha/beta hydrolase fold 104 309 1.6E-52 T 29-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 SMALA_RS01760 c848c08913627a97c2022c412282bf55 336 Gene3D G3DSA:3.40.50.1820 13 336 3.1E-54 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS27280 907703a481b1301fbc1f286511391268 236 Pfam PF00072 Response regulator receiver domain 16 127 9.3E-21 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS27280 907703a481b1301fbc1f286511391268 236 SUPERFAMILY SSF52172 14 166 2.85E-31 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS27280 907703a481b1301fbc1f286511391268 236 PIRSF PIRSF006171 12 236 1.6E-71 T 29-03-2018 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0001071|GO:0003677|GO:0005737|GO:0009605 SMALA_RS27280 907703a481b1301fbc1f286511391268 236 Gene3D G3DSA:3.40.50.2300 13 146 3.6E-28 T 29-03-2018 SMALA_RS27280 907703a481b1301fbc1f286511391268 236 Gene3D G3DSA:1.10.10.10 147 234 2.7E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS27280 907703a481b1301fbc1f286511391268 236 SMART SM00448 14 127 2.1E-22 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS29420 713b602fffa6d53edce2bad0a9fc29c2 316 SUPERFAMILY SSF53901 3 208 1.58E-24 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS29420 713b602fffa6d53edce2bad0a9fc29c2 316 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 33 172 1.3E-14 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS29420 713b602fffa6d53edce2bad0a9fc29c2 316 Gene3D G3DSA:3.40.47.10 1 248 4.8E-27 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS08385 7ce1b5edbcaee35bb7fbb1e13f1db1ac 367 Pfam PF00293 NUDIX domain 210 325 7.8E-15 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SMALA_RS08385 7ce1b5edbcaee35bb7fbb1e13f1db1ac 367 Gene3D G3DSA:3.90.79.10 204 345 2.1E-22 T 29-03-2018 SMALA_RS08385 7ce1b5edbcaee35bb7fbb1e13f1db1ac 367 SUPERFAMILY SSF53335 7 157 9.34E-39 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS08385 7ce1b5edbcaee35bb7fbb1e13f1db1ac 367 Pfam PF08241 Methyltransferase domain 51 144 3.5E-23 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 SMALA_RS08385 7ce1b5edbcaee35bb7fbb1e13f1db1ac 367 SUPERFAMILY SSF55811 206 347 2.71E-23 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMALA_RS08385 7ce1b5edbcaee35bb7fbb1e13f1db1ac 367 ProSitePatterns PS00893 Nudix box signature. 242 263 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 SMALA_RS08385 7ce1b5edbcaee35bb7fbb1e13f1db1ac 367 Gene3D G3DSA:3.40.50.150 2 203 2.9E-37 T 29-03-2018 SMALA_RS04455 62495c81bcdbc4b47cd56515c7287668 127 Pfam PF12840 Helix-turn-helix domain 31 83 2.9E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS04455 62495c81bcdbc4b47cd56515c7287668 127 Gene3D G3DSA:1.10.10.10 2 119 7.0E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS04455 62495c81bcdbc4b47cd56515c7287668 127 SUPERFAMILY SSF46785 18 109 9.99E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS04455 62495c81bcdbc4b47cd56515c7287668 127 SMART SM00418 31 109 1.5E-12 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS04455 62495c81bcdbc4b47cd56515c7287668 127 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 65 80 8.3E-6 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS04455 62495c81bcdbc4b47cd56515c7287668 127 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 33 48 8.3E-6 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS02785 56e97db17c4dd8d38725937833e4b6b6 293 SUPERFAMILY SSF51430 8 279 7.73E-87 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS02785 56e97db17c4dd8d38725937833e4b6b6 293 PRINTS PR00069 Aldo-keto reductase signature 94 112 3.8E-46 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMALA_RS02785 56e97db17c4dd8d38725937833e4b6b6 293 PRINTS PR00069 Aldo-keto reductase signature 210 234 3.8E-46 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMALA_RS02785 56e97db17c4dd8d38725937833e4b6b6 293 PRINTS PR00069 Aldo-keto reductase signature 127 144 3.8E-46 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMALA_RS02785 56e97db17c4dd8d38725937833e4b6b6 293 PRINTS PR00069 Aldo-keto reductase signature 38 62 3.8E-46 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMALA_RS02785 56e97db17c4dd8d38725937833e4b6b6 293 PRINTS PR00069 Aldo-keto reductase signature 161 190 3.8E-46 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMALA_RS02785 56e97db17c4dd8d38725937833e4b6b6 293 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 42 59 - T 29-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 SMALA_RS02785 56e97db17c4dd8d38725937833e4b6b6 293 PIRSF PIRSF000097 1 283 1.1E-81 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMALA_RS02785 56e97db17c4dd8d38725937833e4b6b6 293 Pfam PF00248 Aldo/keto reductase family 25 274 2.0E-42 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS02785 56e97db17c4dd8d38725937833e4b6b6 293 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 243 258 - T 29-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 SMALA_RS02785 56e97db17c4dd8d38725937833e4b6b6 293 Gene3D G3DSA:3.20.20.100 4 283 6.1E-90 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS37550 ae7023656a0b104ec530cbc1a90d5191 462 Gene3D G3DSA:2.60.120.10 73 224 8.3E-19 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SMALA_RS37550 ae7023656a0b104ec530cbc1a90d5191 462 SUPERFAMILY SSF51206 83 206 4.84E-20 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like SMALA_RS37550 ae7023656a0b104ec530cbc1a90d5191 462 Pfam PF00027 Cyclic nucleotide-binding domain 110 196 9.2E-15 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain SMALA_RS37550 ae7023656a0b104ec530cbc1a90d5191 462 SMART SM00100 90 213 5.6E-12 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain SMALA_RS23615 b679e82e19638fe64cf411159e324237 353 Gene3D G3DSA:2.102.10.10 1 109 2.0E-21 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMALA_RS23615 b679e82e19638fe64cf411159e324237 353 Gene3D G3DSA:3.90.380.10 110 348 6.5E-43 T 29-03-2018 SMALA_RS23615 b679e82e19638fe64cf411159e324237 353 SUPERFAMILY SSF55961 107 348 2.2E-37 T 29-03-2018 SMALA_RS23615 b679e82e19638fe64cf411159e324237 353 SUPERFAMILY SSF50022 2 120 1.83E-30 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMALA_RS23615 b679e82e19638fe64cf411159e324237 353 Pfam PF00355 Rieske [2Fe-2S] domain 9 92 9.1E-15 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMALA_RS00095 5cf2072efc26ada1a7a80d2b0c2a226c 153 ProSitePatterns PS00519 AsnC-type HTH domain signature. 19 45 - T 29-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site SMALA_RS00095 5cf2072efc26ada1a7a80d2b0c2a226c 153 Gene3D G3DSA:3.30.70.920 53 147 3.3E-20 T 29-03-2018 SMALA_RS00095 5cf2072efc26ada1a7a80d2b0c2a226c 153 SUPERFAMILY SSF54909 61 143 5.09E-17 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel SMALA_RS00095 5cf2072efc26ada1a7a80d2b0c2a226c 153 Pfam PF13404 AsnC-type helix-turn-helix domain 1 42 9.1E-17 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMALA_RS00095 5cf2072efc26ada1a7a80d2b0c2a226c 153 SUPERFAMILY SSF46785 1 60 1.27E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS00095 5cf2072efc26ada1a7a80d2b0c2a226c 153 SMART SM00344 1 108 5.1E-37 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 SMALA_RS00095 5cf2072efc26ada1a7a80d2b0c2a226c 153 Gene3D G3DSA:1.10.10.10 1 52 1.0E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS00095 5cf2072efc26ada1a7a80d2b0c2a226c 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 8.4E-14 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMALA_RS00095 5cf2072efc26ada1a7a80d2b0c2a226c 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 8.4E-14 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMALA_RS00095 5cf2072efc26ada1a7a80d2b0c2a226c 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 8.4E-14 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMALA_RS00095 5cf2072efc26ada1a7a80d2b0c2a226c 153 Pfam PF01037 Lrp/AsnC ligand binding domain 67 138 5.5E-17 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain SMALA_RS21995 5cf2072efc26ada1a7a80d2b0c2a226c 153 ProSitePatterns PS00519 AsnC-type HTH domain signature. 19 45 - T 29-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site SMALA_RS21995 5cf2072efc26ada1a7a80d2b0c2a226c 153 Gene3D G3DSA:3.30.70.920 53 147 3.3E-20 T 29-03-2018 SMALA_RS21995 5cf2072efc26ada1a7a80d2b0c2a226c 153 SUPERFAMILY SSF54909 61 143 5.09E-17 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel SMALA_RS21995 5cf2072efc26ada1a7a80d2b0c2a226c 153 Pfam PF13404 AsnC-type helix-turn-helix domain 1 42 9.1E-17 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMALA_RS21995 5cf2072efc26ada1a7a80d2b0c2a226c 153 SUPERFAMILY SSF46785 1 60 1.27E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS21995 5cf2072efc26ada1a7a80d2b0c2a226c 153 SMART SM00344 1 108 5.1E-37 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 SMALA_RS21995 5cf2072efc26ada1a7a80d2b0c2a226c 153 Gene3D G3DSA:1.10.10.10 1 52 1.0E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS21995 5cf2072efc26ada1a7a80d2b0c2a226c 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 8.4E-14 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMALA_RS21995 5cf2072efc26ada1a7a80d2b0c2a226c 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 8.4E-14 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMALA_RS21995 5cf2072efc26ada1a7a80d2b0c2a226c 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 8.4E-14 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMALA_RS21995 5cf2072efc26ada1a7a80d2b0c2a226c 153 Pfam PF01037 Lrp/AsnC ligand binding domain 67 138 5.5E-17 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain SMALA_RS07155 ecd92591bf88ea2e951c87796d852bf5 873 SUPERFAMILY SSF53850 615 868 4.78E-67 T 29-03-2018 SMALA_RS07155 ecd92591bf88ea2e951c87796d852bf5 873 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 105 272 1.9E-25 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS07155 ecd92591bf88ea2e951c87796d852bf5 873 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 615 859 7.9E-59 T 29-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 SMALA_RS07155 ecd92591bf88ea2e951c87796d852bf5 873 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 339 587 6.0E-64 T 29-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 SMALA_RS07155 ecd92591bf88ea2e951c87796d852bf5 873 Gene3D G3DSA:3.40.190.10 331 431 1.0E-14 T 29-03-2018 SMALA_RS07155 ecd92591bf88ea2e951c87796d852bf5 873 Gene3D G3DSA:3.40.190.10 606 706 2.9E-13 T 29-03-2018 SMALA_RS07155 ecd92591bf88ea2e951c87796d852bf5 873 SUPERFAMILY SSF53850 335 594 3.87E-70 T 29-03-2018 SMALA_RS07155 ecd92591bf88ea2e951c87796d852bf5 873 Gene3D G3DSA:1.10.3720.10 23 279 2.0E-32 T 29-03-2018 SMALA_RS07155 ecd92591bf88ea2e951c87796d852bf5 873 Gene3D G3DSA:3.40.190.100 707 819 2.2E-34 T 29-03-2018 SMALA_RS07155 ecd92591bf88ea2e951c87796d852bf5 873 Gene3D G3DSA:3.40.190.100 432 546 9.2E-35 T 29-03-2018 SMALA_RS07155 ecd92591bf88ea2e951c87796d852bf5 873 SUPERFAMILY SSF161098 83 265 1.57E-39 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS24820 6c4f4a62135920d453c430068e6da35c 598 SUPERFAMILY SSF51658 1 266 6.91E-73 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SMALA_RS24820 6c4f4a62135920d453c430068e6da35c 598 Gene3D G3DSA:3.20.20.150 1 266 5.0E-54 T 29-03-2018 SMALA_RS24820 6c4f4a62135920d453c430068e6da35c 598 Gene3D G3DSA:3.10.180.10 415 596 5.5E-36 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS24820 6c4f4a62135920d453c430068e6da35c 598 Gene3D G3DSA:3.10.180.10 296 414 7.7E-4 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS24820 6c4f4a62135920d453c430068e6da35c 598 Pfam PF01261 Xylose isomerase-like TIM barrel 18 217 1.2E-37 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SMALA_RS24820 6c4f4a62135920d453c430068e6da35c 598 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 420 535 3.5E-10 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMALA_RS24820 6c4f4a62135920d453c430068e6da35c 598 SUPERFAMILY SSF54593 299 593 6.12E-46 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS08535 eaeea2bd24885b7ceb587944dc7a5686 253 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS08535 eaeea2bd24885b7ceb587944dc7a5686 253 SUPERFAMILY SSF52540 4 248 2.54E-77 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS08535 eaeea2bd24885b7ceb587944dc7a5686 253 Gene3D G3DSA:3.40.50.300 1 253 2.9E-76 T 29-03-2018 SMALA_RS08535 eaeea2bd24885b7ceb587944dc7a5686 253 Pfam PF00005 ABC transporter 20 178 1.4E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS08535 eaeea2bd24885b7ceb587944dc7a5686 253 SMART SM00382 29 226 6.8E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS08535 eaeea2bd24885b7ceb587944dc7a5686 253 PIRSF PIRSF039085 1 253 1.3E-115 T 29-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 SMALA_RS15145 fe8d9446646909a017a02285b16545ae 474 Pfam PF07690 Major Facilitator Superfamily 249 418 1.3E-20 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS15145 fe8d9446646909a017a02285b16545ae 474 ProSitePatterns PS00216 Sugar transport proteins signature 1. 79 95 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMALA_RS15145 fe8d9446646909a017a02285b16545ae 474 Gene3D G3DSA:1.20.1250.20 21 216 4.6E-17 T 29-03-2018 SMALA_RS15145 fe8d9446646909a017a02285b16545ae 474 Gene3D G3DSA:1.20.1250.20 232 424 1.6E-25 T 29-03-2018 SMALA_RS15145 fe8d9446646909a017a02285b16545ae 474 SUPERFAMILY SSF103473 22 418 2.75E-48 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS11780 57fc4790e5b0b66980dd0e6164bcdd47 214 Pfam PF13649 Methyltransferase domain 28 120 7.1E-19 T 29-03-2018 SMALA_RS11780 57fc4790e5b0b66980dd0e6164bcdd47 214 Gene3D G3DSA:3.40.50.150 9 190 1.4E-27 T 29-03-2018 SMALA_RS11780 57fc4790e5b0b66980dd0e6164bcdd47 214 SUPERFAMILY SSF53335 6 133 1.86E-30 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS34315 d3028f3d2729aea2046acda1f49ddae0 336 Gene3D G3DSA:1.10.10.60 2 16 0.0015 T 29-03-2018 SMALA_RS34315 d3028f3d2729aea2046acda1f49ddae0 336 SUPERFAMILY SSF53822 60 333 1.99E-72 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SMALA_RS34315 d3028f3d2729aea2046acda1f49ddae0 336 SMART SM00354 1 70 7.1E-26 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS34315 d3028f3d2729aea2046acda1f49ddae0 336 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 47 1.8E-11 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS34315 d3028f3d2729aea2046acda1f49ddae0 336 SUPERFAMILY SSF47413 2 58 3.75E-13 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS34315 d3028f3d2729aea2046acda1f49ddae0 336 Gene3D G3DSA:1.10.260.40 17 53 6.5E-20 T 29-03-2018 SMALA_RS34315 d3028f3d2729aea2046acda1f49ddae0 336 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 6.5E-6 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS34315 d3028f3d2729aea2046acda1f49ddae0 336 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 6.5E-6 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS34315 d3028f3d2729aea2046acda1f49ddae0 336 Gene3D G3DSA:3.40.50.2300 174 312 2.2E-39 T 29-03-2018 SMALA_RS34315 d3028f3d2729aea2046acda1f49ddae0 336 Pfam PF00532 Periplasmic binding proteins and sugar binding domain of LacI family 60 306 3.7E-30 T 29-03-2018 IPR001761 Periplasmic binding protein/LacI sugar binding domain SMALA_RS34315 d3028f3d2729aea2046acda1f49ddae0 336 Gene3D G3DSA:3.40.50.2300 54 173 2.2E-41 T 29-03-2018 SMALA_RS23660 0559a657a82e0c6ea79d3b17bf2d7591 360 Pfam PF14027 Protein of unknown function (DUF4243) 27 333 2.2E-38 T 29-03-2018 IPR025337 Domain of unknown function DUF4243 SMALA_RS23355 b91468dcd0be7d1e555d860a373b358a 140 Gene3D G3DSA:3.30.530.20 7 140 9.3E-33 T 29-03-2018 IPR023393 START-like domain SMALA_RS23355 b91468dcd0be7d1e555d860a373b358a 140 SUPERFAMILY SSF55961 4 136 1.94E-36 T 29-03-2018 SMALA_RS23355 b91468dcd0be7d1e555d860a373b358a 140 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 18 135 1.1E-22 T 29-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 SMALA_RS42475 fe3e2f070c02c8b641946f003b9769cd 227 Pfam PF01323 DSBA-like thioredoxin domain 14 210 6.9E-32 T 29-03-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 SMALA_RS42475 fe3e2f070c02c8b641946f003b9769cd 227 SUPERFAMILY SSF52833 13 218 2.5E-36 T 29-03-2018 IPR012336 Thioredoxin-like fold SMALA_RS42475 fe3e2f070c02c8b641946f003b9769cd 227 Gene3D G3DSA:3.40.30.10 11 227 4.1E-46 T 29-03-2018 SMALA_RS16385 4c176b999bc98a3fbb44fea610b2e24d 145 Pfam PF13772 AIG2-like family 59 140 1.8E-20 T 29-03-2018 SMALA_RS16385 4c176b999bc98a3fbb44fea610b2e24d 145 SUPERFAMILY SSF110857 1 119 4.97E-14 T 29-03-2018 IPR013024 Gamma-glutamyl cyclotransferase-like SMALA_RS16385 4c176b999bc98a3fbb44fea610b2e24d 145 Gene3D G3DSA:3.10.490.10 1 144 1.2E-31 T 29-03-2018 SMALA_RS09665 28ad91a547df6c5351969c3a01708ea6 296 SUPERFAMILY SSF51695 40 292 6.54E-72 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 SMALA_RS09665 28ad91a547df6c5351969c3a01708ea6 296 Gene3D G3DSA:3.20.20.190 20 296 2.4E-73 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 SMALA_RS09665 28ad91a547df6c5351969c3a01708ea6 296 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 45 286 1.3E-42 T 29-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 SMALA_RS30475 e2127dcfd998ff1194dd40ad473de036 296 SMART SM00148 52 186 4.8E-8 T 29-03-2018 IPR000909 Phosphatidylinositol-specific phospholipase C, X domain SMALA_RS30475 e2127dcfd998ff1194dd40ad473de036 296 SUPERFAMILY SSF51695 39 293 8.02E-48 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 SMALA_RS30475 e2127dcfd998ff1194dd40ad473de036 296 Pfam PF00388 Phosphatidylinositol-specific phospholipase C, X domain 70 183 4.7E-12 T 29-03-2018 IPR000909 Phosphatidylinositol-specific phospholipase C, X domain SMALA_RS30475 e2127dcfd998ff1194dd40ad473de036 296 Gene3D G3DSA:3.20.20.190 34 295 2.9E-46 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 SMALA_RS10505 996f9bcb676ccc1aba8c7abc2fc2c8d1 93 Pfam PF01037 Lrp/AsnC ligand binding domain 6 77 6.9E-17 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain SMALA_RS10505 996f9bcb676ccc1aba8c7abc2fc2c8d1 93 Gene3D G3DSA:3.30.70.920 1 83 2.7E-19 T 29-03-2018 SMALA_RS10505 996f9bcb676ccc1aba8c7abc2fc2c8d1 93 SUPERFAMILY SSF54909 3 78 3.43E-18 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel SMALA_RS14745 2efa962258b72ae4d6073a6624484eca 412 Gene3D G3DSA:3.40.47.10 2 258 3.8E-59 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS14745 2efa962258b72ae4d6073a6624484eca 412 Gene3D G3DSA:3.40.47.10 262 411 4.4E-43 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS14745 2efa962258b72ae4d6073a6624484eca 412 SMART SM00825 Beta-ketoacyl synthase 9 409 5.2E-15 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS14745 2efa962258b72ae4d6073a6624484eca 412 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 254 364 5.1E-33 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS14745 2efa962258b72ae4d6073a6624484eca 412 SUPERFAMILY SSF53901 217 405 6.84E-63 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS14745 2efa962258b72ae4d6073a6624484eca 412 SUPERFAMILY SSF53901 7 251 2.03E-48 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS14745 2efa962258b72ae4d6073a6624484eca 412 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 7 246 5.9E-34 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS09925 cfd7403c3b115abe73b53806bdc066e5 140 SMART SM00345 18 77 1.3E-14 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS09925 cfd7403c3b115abe73b53806bdc066e5 140 SUPERFAMILY SSF46785 7 79 1.1E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS09925 cfd7403c3b115abe73b53806bdc066e5 140 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 77 6.8E-15 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS09925 cfd7403c3b115abe73b53806bdc066e5 140 Gene3D G3DSA:1.10.10.10 1 79 6.2E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS30635 4b2eaff9679696cb0350ccac357af226 350 Gene3D G3DSA:1.10.3470.10 51 341 4.4E-18 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SMALA_RS30635 4b2eaff9679696cb0350ccac357af226 350 Pfam PF02653 Branched-chain amino acid transport system / permease component 59 335 1.2E-51 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 SMALA_RS33090 a195fbee6b82801942a5098f890afab3 431 SUPERFAMILY SSF51338 370 430 2.02E-22 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS33090 a195fbee6b82801942a5098f890afab3 431 SUPERFAMILY SSF51338 6 53 2.02E-22 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS33090 a195fbee6b82801942a5098f890afab3 431 Gene3D G3DSA:2.30.40.10 4 67 3.3E-21 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS33090 a195fbee6b82801942a5098f890afab3 431 SUPERFAMILY SSF51556 54 368 5.11E-99 T 29-03-2018 IPR032466 Metal-dependent hydrolase SMALA_RS33090 a195fbee6b82801942a5098f890afab3 431 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 20 427 2.6E-126 T 29-03-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SMALA_RS33090 a195fbee6b82801942a5098f890afab3 431 Gene3D G3DSA:3.20.20.140 68 410 4.3E-91 T 29-03-2018 SMALA_RS33090 a195fbee6b82801942a5098f890afab3 431 ProSitePatterns PS00483 Dihydroorotase signature 2. 304 315 - T 29-03-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SMALA_RS33090 a195fbee6b82801942a5098f890afab3 431 Pfam PF01979 Amidohydrolase family 50 422 4.3E-16 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 SMALA_RS33090 a195fbee6b82801942a5098f890afab3 431 Hamap MF_00220_B Dihydroorotase [pyrC]. 6 428 42.738 T 29-03-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SMALA_RS11375 5133562ba97f30bcbc73b368f3f4283c 317 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 169 4.3E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS11375 5133562ba97f30bcbc73b368f3f4283c 317 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 98 109 4.3E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS11375 5133562ba97f30bcbc73b368f3f4283c 317 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 4.3E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS11375 5133562ba97f30bcbc73b368f3f4283c 317 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 198 4.3E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS11375 5133562ba97f30bcbc73b368f3f4283c 317 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 229 249 4.3E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS11375 5133562ba97f30bcbc73b368f3f4283c 317 Pfam PF00106 short chain dehydrogenase 12 218 1.1E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS11375 5133562ba97f30bcbc73b368f3f4283c 317 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 12 214 0.0031 T 29-03-2018 SMALA_RS11375 5133562ba97f30bcbc73b368f3f4283c 317 SUPERFAMILY SSF51735 8 269 2.94E-63 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS11375 5133562ba97f30bcbc73b368f3f4283c 317 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 166 194 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMALA_RS11375 5133562ba97f30bcbc73b368f3f4283c 317 Gene3D G3DSA:3.40.50.720 7 310 4.6E-60 T 29-03-2018 SMALA_RS11375 5133562ba97f30bcbc73b368f3f4283c 317 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 167 7.3E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS11375 5133562ba97f30bcbc73b368f3f4283c 317 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 179 198 7.3E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS11375 5133562ba97f30bcbc73b368f3f4283c 317 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 98 109 7.3E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS28815 235252985ffe721f6468d8dbb74c2d3c 379 Gene3D G3DSA:3.40.50.300 27 269 1.2E-48 T 29-03-2018 SMALA_RS28815 235252985ffe721f6468d8dbb74c2d3c 379 Gene3D G3DSA:3.30.250.10 271 327 1.2E-27 T 29-03-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal SMALA_RS28815 235252985ffe721f6468d8dbb74c2d3c 379 Hamap MF_00268 Protein RecA [recA]. 6 330 52.714 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 SMALA_RS28815 235252985ffe721f6468d8dbb74c2d3c 379 ProSitePatterns PS00321 recA signature. 214 222 - T 29-03-2018 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 SMALA_RS28815 235252985ffe721f6468d8dbb74c2d3c 379 Pfam PF00154 recA bacterial DNA recombination protein 8 269 8.1E-142 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 SMALA_RS28815 235252985ffe721f6468d8dbb74c2d3c 379 SMART SM00382 58 229 1.9E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS28815 235252985ffe721f6468d8dbb74c2d3c 379 SUPERFAMILY SSF52540 5 268 7.16E-69 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS28815 235252985ffe721f6468d8dbb74c2d3c 379 SUPERFAMILY SSF54752 269 327 1.18E-21 T 29-03-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal SMALA_RS28815 235252985ffe721f6468d8dbb74c2d3c 379 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 5 325 2.3E-174 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 SMALA_RS28815 235252985ffe721f6468d8dbb74c2d3c 379 PRINTS PR00142 RecA protein signature 94 123 1.5E-85 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 SMALA_RS28815 235252985ffe721f6468d8dbb74c2d3c 379 PRINTS PR00142 RecA protein signature 298 315 1.5E-85 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 SMALA_RS28815 235252985ffe721f6468d8dbb74c2d3c 379 PRINTS PR00142 RecA protein signature 128 157 1.5E-85 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 SMALA_RS28815 235252985ffe721f6468d8dbb74c2d3c 379 PRINTS PR00142 RecA protein signature 166 195 1.5E-85 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 SMALA_RS28815 235252985ffe721f6468d8dbb74c2d3c 379 PRINTS PR00142 RecA protein signature 244 273 1.5E-85 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 SMALA_RS28815 235252985ffe721f6468d8dbb74c2d3c 379 PRINTS PR00142 RecA protein signature 211 239 1.5E-85 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 SMALA_RS42935 46c50685bdaa83bf46c9d6ac79fd052a 71 SUPERFAMILY SSF160582 2 66 1.44E-25 T 29-03-2018 SMALA_RS42935 46c50685bdaa83bf46c9d6ac79fd052a 71 Pfam PF03621 MbtH-like protein 2 52 3.2E-25 T 29-03-2018 IPR005153 MbtH-like protein SMALA_RS42935 46c50685bdaa83bf46c9d6ac79fd052a 71 Gene3D G3DSA:3.90.820.10 1 67 7.9E-30 T 29-03-2018 SMALA_RS42935 46c50685bdaa83bf46c9d6ac79fd052a 71 SMART SM00923 2 52 2.4E-27 T 29-03-2018 IPR005153 MbtH-like protein SMALA_RS34005 5d5fa3033e6e947e81d12858ff150cae 462 Pfam PF00067 Cytochrome P450 300 387 1.2E-7 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS34005 5d5fa3033e6e947e81d12858ff150cae 462 Gene3D G3DSA:1.10.630.10 11 272 4.2E-19 T 29-03-2018 SMALA_RS34005 5d5fa3033e6e947e81d12858ff150cae 462 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 355 364 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMALA_RS34005 5d5fa3033e6e947e81d12858ff150cae 462 Gene3D G3DSA:1.10.630.10 296 421 1.5E-17 T 29-03-2018 SMALA_RS34005 5d5fa3033e6e947e81d12858ff150cae 462 PRINTS PR00359 B-class P450 signature 353 362 6.7E-14 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS34005 5d5fa3033e6e947e81d12858ff150cae 462 PRINTS PR00359 B-class P450 signature 305 332 6.7E-14 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS34005 5d5fa3033e6e947e81d12858ff150cae 462 PRINTS PR00359 B-class P450 signature 159 175 6.7E-14 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS34005 5d5fa3033e6e947e81d12858ff150cae 462 PRINTS PR00359 B-class P450 signature 210 232 6.7E-14 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS34005 5d5fa3033e6e947e81d12858ff150cae 462 SUPERFAMILY SSF48264 18 415 2.23E-49 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS22190 40c06a8fc733037fc6ba2746a8efc33e 400 SUPERFAMILY SSF51905 5 396 1.3E-29 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS22190 40c06a8fc733037fc6ba2746a8efc33e 400 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 216 8.4E-14 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS22190 40c06a8fc733037fc6ba2746a8efc33e 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 7.4E-8 T 29-03-2018 SMALA_RS22190 40c06a8fc733037fc6ba2746a8efc33e 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 181 199 7.4E-8 T 29-03-2018 SMALA_RS22190 40c06a8fc733037fc6ba2746a8efc33e 400 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 2.3E-7 T 29-03-2018 SMALA_RS22190 40c06a8fc733037fc6ba2746a8efc33e 400 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 181 206 2.3E-7 T 29-03-2018 SMALA_RS22190 40c06a8fc733037fc6ba2746a8efc33e 400 Gene3D G3DSA:3.50.50.60 5 170 2.1E-18 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS22190 40c06a8fc733037fc6ba2746a8efc33e 400 Gene3D G3DSA:3.50.50.60 171 398 5.6E-18 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS32980 d0a7e27e787697d59733f681703d9923 286 PIRSF PIRSF006648 4 285 4.7E-28 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMALA_RS32980 d0a7e27e787697d59733f681703d9923 286 Pfam PF01061 ABC-2 type transporter 36 240 2.2E-23 T 29-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 SMALA_RS18490 776f737be80a1e2553047251aa632289 405 Gene3D G3DSA:3.40.50.300 4 191 2.1E-26 T 29-03-2018 SMALA_RS18490 776f737be80a1e2553047251aa632289 405 Gene3D G3DSA:1.20.272.10 303 404 4.1E-26 T 29-03-2018 SMALA_RS18490 776f737be80a1e2553047251aa632289 405 SMART SM00382 45 191 0.0013 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS18490 776f737be80a1e2553047251aa632289 405 Pfam PF13177 DNA polymerase III, delta subunit 40 190 2.1E-34 T 29-03-2018 SMALA_RS18490 776f737be80a1e2553047251aa632289 405 SUPERFAMILY SSF52540 4 229 6.43E-43 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS08125 fe208027903abb6b4cbe4b591b9a4c02 404 Gene3D G3DSA:1.10.540.10 1 133 4.0E-32 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS08125 fe208027903abb6b4cbe4b591b9a4c02 404 Gene3D G3DSA:1.20.140.10 238 404 2.2E-43 T 29-03-2018 SMALA_RS08125 fe208027903abb6b4cbe4b591b9a4c02 404 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 134 237 5.1E-21 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 SMALA_RS08125 fe208027903abb6b4cbe4b591b9a4c02 404 Gene3D G3DSA:2.40.110.10 134 237 1.3E-33 T 29-03-2018 SMALA_RS08125 fe208027903abb6b4cbe4b591b9a4c02 404 SUPERFAMILY SSF47203 247 403 2.9E-40 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMALA_RS08125 fe208027903abb6b4cbe4b591b9a4c02 404 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 249 399 1.5E-32 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMALA_RS08125 fe208027903abb6b4cbe4b591b9a4c02 404 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 130 7.0E-14 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS08125 fe208027903abb6b4cbe4b591b9a4c02 404 SUPERFAMILY SSF56645 1 262 1.57E-63 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMALA_RS09365 995ada637e174a7fa9ffcda0fa335185 315 SUPERFAMILY SSF51569 9 301 1.36E-66 T 29-03-2018 SMALA_RS09365 995ada637e174a7fa9ffcda0fa335185 315 Hamap MF_00694 Probable 5-dehydro-4-deoxyglucarate dehydratase. 9 304 44.864 T 29-03-2018 IPR017655 5-dehydro-4-deoxyglucarate dehydratase GO:0016052|GO:0047448 KEGG: 00053+4.2.1.41|MetaCyc: PWY-6486|MetaCyc: PWY-6497|MetaCyc: PWY-6499|MetaCyc: PWY-6501 SMALA_RS09365 995ada637e174a7fa9ffcda0fa335185 315 SMART SM01130 9 303 3.2E-75 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SMALA_RS09365 995ada637e174a7fa9ffcda0fa335185 315 Pfam PF00701 Dihydrodipicolinate synthetase family 11 301 1.1E-55 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SMALA_RS09365 995ada637e174a7fa9ffcda0fa335185 315 Gene3D G3DSA:3.20.20.70 7 306 3.1E-70 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS09365 995ada637e174a7fa9ffcda0fa335185 315 PIRSF PIRSF001365 6 313 2.9E-58 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SMALA_RS31665 589dcf729855ef6a018123f2de784d4a 351 SUPERFAMILY SSF53822 95 336 2.36E-32 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SMALA_RS31665 589dcf729855ef6a018123f2de784d4a 351 Gene3D G3DSA:1.10.260.40 23 78 1.7E-17 T 29-03-2018 SMALA_RS31665 589dcf729855ef6a018123f2de784d4a 351 ProSitePatterns PS00356 LacI-type HTH domain signature. 27 45 - T 29-03-2018 SMALA_RS31665 589dcf729855ef6a018123f2de784d4a 351 Gene3D G3DSA:3.40.50.2300 185 345 4.5E-29 T 29-03-2018 SMALA_RS31665 589dcf729855ef6a018123f2de784d4a 351 SMART SM00354 24 86 1.3E-9 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS31665 589dcf729855ef6a018123f2de784d4a 351 SUPERFAMILY SSF47413 23 77 1.04E-13 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS31665 589dcf729855ef6a018123f2de784d4a 351 Pfam PF13377 Periplasmic binding protein-like domain 186 342 1.4E-28 T 29-03-2018 SMALA_RS31665 589dcf729855ef6a018123f2de784d4a 351 Pfam PF00356 Bacterial regulatory proteins, lacI family 26 70 6.2E-16 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS31665 589dcf729855ef6a018123f2de784d4a 351 Gene3D G3DSA:3.40.50.2300 79 184 2.0E-15 T 29-03-2018 SMALA_RS20170 004658cf73f7cd6e55f1d4b28351897e 672 Gene3D G3DSA:3.40.50.410 468 661 8.5E-14 T 29-03-2018 IPR002035 von Willebrand factor, type A SMALA_RS20170 004658cf73f7cd6e55f1d4b28351897e 672 Pfam PF10138 vWA found in TerF C terminus 471 670 1.1E-54 T 29-03-2018 IPR019303 vWA found in TerF C terminus SMALA_RS20170 004658cf73f7cd6e55f1d4b28351897e 672 SUPERFAMILY SSF53300 473 620 5.56E-12 T 29-03-2018 IPR002035 von Willebrand factor, type A SMALA_RS20170 004658cf73f7cd6e55f1d4b28351897e 672 SMART SM00327 470 639 3.4E-5 T 29-03-2018 IPR002035 von Willebrand factor, type A SMALA_RS23295 5ef5dc8dc33435d2082468473e8fefdd 518 SUPERFAMILY SSF53300 62 226 1.63E-21 T 29-03-2018 IPR002035 von Willebrand factor, type A SMALA_RS23295 5ef5dc8dc33435d2082468473e8fefdd 518 SMART SM00327 58 236 5.6E-12 T 29-03-2018 IPR002035 von Willebrand factor, type A SMALA_RS23295 5ef5dc8dc33435d2082468473e8fefdd 518 Gene3D G3DSA:3.40.50.410 59 240 1.9E-22 T 29-03-2018 IPR002035 von Willebrand factor, type A SMALA_RS23295 5ef5dc8dc33435d2082468473e8fefdd 518 Pfam PF13768 von Willebrand factor type A domain 62 218 2.5E-13 T 29-03-2018 IPR002035 von Willebrand factor, type A SMALA_RS08380 40754f6f35b744364e1f70a3713ced92 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 47 70 8.1E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS08380 40754f6f35b744364e1f70a3713ced92 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 40 8.1E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS08380 40754f6f35b744364e1f70a3713ced92 197 Gene3D G3DSA:1.10.357.10 75 192 1.8E-14 T 29-03-2018 SMALA_RS08380 40754f6f35b744364e1f70a3713ced92 197 Gene3D G3DSA:1.10.10.60 11 53 3.0E-14 T 29-03-2018 SMALA_RS08380 40754f6f35b744364e1f70a3713ced92 197 Gene3D G3DSA:1.10.260.40 54 74 4.0E-10 T 29-03-2018 SMALA_RS08380 40754f6f35b744364e1f70a3713ced92 197 SUPERFAMILY SSF48498 93 193 2.53E-9 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS08380 40754f6f35b744364e1f70a3713ced92 197 SUPERFAMILY SSF46689 14 95 1.8E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS08380 40754f6f35b744364e1f70a3713ced92 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 72 2.9E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS27245 1c2f6ba77467d9f65848c12d0f70f2e2 293 Pfam PF13560 Helix-turn-helix domain 20 77 5.2E-9 T 29-03-2018 SMALA_RS27245 1c2f6ba77467d9f65848c12d0f70f2e2 293 Gene3D G3DSA:1.10.260.40 9 82 1.2E-7 T 29-03-2018 SMALA_RS27245 1c2f6ba77467d9f65848c12d0f70f2e2 293 SUPERFAMILY SSF47413 19 74 1.13E-5 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS19235 9d7da6d0c2b642fe03ee1e4b75daff9f 534 SUPERFAMILY SSF50156 419 527 1.31E-16 T 29-03-2018 IPR001478 PDZ domain GO:0005515 SMALA_RS19235 9d7da6d0c2b642fe03ee1e4b75daff9f 534 Gene3D G3DSA:2.40.10.10 212 319 2.5E-29 T 29-03-2018 SMALA_RS19235 9d7da6d0c2b642fe03ee1e4b75daff9f 534 Gene3D G3DSA:2.30.42.10 432 534 1.2E-18 T 29-03-2018 SMALA_RS19235 9d7da6d0c2b642fe03ee1e4b75daff9f 534 Gene3D G3DSA:2.40.10.10 320 431 1.9E-36 T 29-03-2018 SMALA_RS19235 9d7da6d0c2b642fe03ee1e4b75daff9f 534 Pfam PF13365 Trypsin-like peptidase domain 243 389 2.8E-33 T 29-03-2018 SMALA_RS19235 9d7da6d0c2b642fe03ee1e4b75daff9f 534 Pfam PF13180 PDZ domain 439 527 1.2E-23 T 29-03-2018 IPR001478 PDZ domain GO:0005515 SMALA_RS19235 9d7da6d0c2b642fe03ee1e4b75daff9f 534 SUPERFAMILY SSF50494 216 431 5.49E-56 T 29-03-2018 IPR009003 Peptidase S1, PA clan SMALA_RS19235 9d7da6d0c2b642fe03ee1e4b75daff9f 534 PRINTS PR00834 HtrA/DegQ protease family signature 360 377 1.7E-44 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMALA_RS19235 9d7da6d0c2b642fe03ee1e4b75daff9f 534 PRINTS PR00834 HtrA/DegQ protease family signature 382 399 1.7E-44 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMALA_RS19235 9d7da6d0c2b642fe03ee1e4b75daff9f 534 PRINTS PR00834 HtrA/DegQ protease family signature 319 343 1.7E-44 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMALA_RS19235 9d7da6d0c2b642fe03ee1e4b75daff9f 534 PRINTS PR00834 HtrA/DegQ protease family signature 252 264 1.7E-44 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMALA_RS19235 9d7da6d0c2b642fe03ee1e4b75daff9f 534 PRINTS PR00834 HtrA/DegQ protease family signature 276 296 1.7E-44 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMALA_RS19235 9d7da6d0c2b642fe03ee1e4b75daff9f 534 PRINTS PR00834 HtrA/DegQ protease family signature 476 488 1.7E-44 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMALA_RS19235 9d7da6d0c2b642fe03ee1e4b75daff9f 534 SMART SM00228 449 518 7.8E-5 T 29-03-2018 IPR001478 PDZ domain GO:0005515 SMALA_RS39325 6dea0cfee25ad79faf98a329c78e76a1 339 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 88 1.5E-7 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS39325 6dea0cfee25ad79faf98a329c78e76a1 339 Pfam PF00107 Zinc-binding dehydrogenase 164 292 1.1E-24 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMALA_RS39325 6dea0cfee25ad79faf98a329c78e76a1 339 Gene3D G3DSA:3.40.50.720 160 274 4.0E-17 T 29-03-2018 SMALA_RS39325 6dea0cfee25ad79faf98a329c78e76a1 339 SUPERFAMILY SSF51735 119 294 1.41E-31 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS39325 6dea0cfee25ad79faf98a329c78e76a1 339 SUPERFAMILY SSF50129 1 139 1.19E-33 T 29-03-2018 IPR011032 GroES-like SMALA_RS39325 6dea0cfee25ad79faf98a329c78e76a1 339 Gene3D G3DSA:3.90.180.10 1 159 1.1E-43 T 29-03-2018 SMALA_RS39325 6dea0cfee25ad79faf98a329c78e76a1 339 SMART SM00829 10 335 5.8E-12 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS02780 ea5aa30b826b737118e67e53bd5751b2 290 SMART SM00530 12 84 3.8E-8 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS02780 ea5aa30b826b737118e67e53bd5751b2 290 Gene3D G3DSA:1.10.260.40 4 93 1.8E-15 T 29-03-2018 SMALA_RS02780 ea5aa30b826b737118e67e53bd5751b2 290 SUPERFAMILY SSF47413 32 83 1.57E-7 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS02780 ea5aa30b826b737118e67e53bd5751b2 290 Pfam PF13560 Helix-turn-helix domain 8 87 9.7E-17 T 29-03-2018 SMALA_RS26405 bacba1ba63fdeb32494dc3f1a09f505e 130 Pfam PF01740 STAS domain 15 105 6.6E-12 T 29-03-2018 IPR002645 STAS domain SMALA_RS26405 bacba1ba63fdeb32494dc3f1a09f505e 130 SUPERFAMILY SSF52091 10 115 1.1E-19 T 29-03-2018 IPR002645 STAS domain SMALA_RS26405 bacba1ba63fdeb32494dc3f1a09f505e 130 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 10 108 2.1E-16 T 29-03-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 SMALA_RS26405 bacba1ba63fdeb32494dc3f1a09f505e 130 Gene3D G3DSA:3.30.750.24 5 122 8.3E-18 T 29-03-2018 IPR002645 STAS domain SMALA_RS20025 c66560d5372ecc2b3fb81d83573b5d44 404 ProSitePatterns PS01043 Transposases, IS30 family, signature. 346 362 - T 29-03-2018 IPR001598 Transposase, IS30, conserved site GO:0003677|GO:0004803|GO:0006313 SMALA_RS20025 c66560d5372ecc2b3fb81d83573b5d44 404 Gene3D G3DSA:1.10.10.10 18 66 4.2E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS20025 c66560d5372ecc2b3fb81d83573b5d44 404 Pfam PF13936 Helix-turn-helix domain 78 119 3.9E-14 T 29-03-2018 IPR025246 Transposase IS30-like HTH domain SMALA_RS20025 c66560d5372ecc2b3fb81d83573b5d44 404 Gene3D G3DSA:3.30.420.10 244 404 2.4E-22 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SMALA_RS20025 c66560d5372ecc2b3fb81d83573b5d44 404 SUPERFAMILY SSF46689 77 179 3.11E-6 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS20025 c66560d5372ecc2b3fb81d83573b5d44 404 Gene3D G3DSA:1.10.10.10 74 132 1.6E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS20025 c66560d5372ecc2b3fb81d83573b5d44 404 Pfam PF00665 Integrase core domain 253 359 2.2E-12 T 29-03-2018 IPR001584 Integrase, catalytic core GO:0015074 SMALA_RS20025 c66560d5372ecc2b3fb81d83573b5d44 404 SUPERFAMILY SSF53098 252 400 8.65E-25 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SMALA_RS20025 c66560d5372ecc2b3fb81d83573b5d44 404 Gene3D G3DSA:1.10.10.60 139 197 0.33 T 29-03-2018 SMALA_RS42325 003ca84128bd4376d9453e6f0762c4ff 204 SUPERFAMILY SSF46689 7 87 6.16E-18 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS42325 003ca84128bd4376d9453e6f0762c4ff 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 1.3E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS42325 003ca84128bd4376d9453e6f0762c4ff 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 1.3E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS42325 003ca84128bd4376d9453e6f0762c4ff 204 SUPERFAMILY SSF48498 86 198 7.12E-23 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS42325 003ca84128bd4376d9453e6f0762c4ff 204 Gene3D G3DSA:1.10.260.40 42 78 5.8E-8 T 29-03-2018 SMALA_RS42325 003ca84128bd4376d9453e6f0762c4ff 204 Pfam PF16925 Bacterial transcriptional repressor C-terminal 88 195 5.4E-11 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS42325 003ca84128bd4376d9453e6f0762c4ff 204 Gene3D G3DSA:1.10.10.60 5 41 3.9E-14 T 29-03-2018 SMALA_RS42325 003ca84128bd4376d9453e6f0762c4ff 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 65 2.2E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS42325 003ca84128bd4376d9453e6f0762c4ff 204 Gene3D G3DSA:1.10.357.10 79 203 1.8E-19 T 29-03-2018 SMALA_RS42130 18a123f809ff4dc2b4476383416fa8c2 344 SUPERFAMILY SSF51569 6 271 5.86E-38 T 29-03-2018 SMALA_RS42130 18a123f809ff4dc2b4476383416fa8c2 344 Gene3D G3DSA:3.20.20.70 7 317 1.1E-38 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS42130 18a123f809ff4dc2b4476383416fa8c2 344 Pfam PF00682 HMGL-like 132 266 2.0E-21 T 29-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 SMALA_RS21215 e2841c4405b3469a7801018d8b516bf3 1375 SUPERFAMILY SSF46894 4 90 1.7E-5 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS21215 e2841c4405b3469a7801018d8b516bf3 1375 Pfam PF03704 Bacterial transcriptional activator domain 99 241 9.8E-40 T 29-03-2018 IPR005158 Bacterial transcriptional activator domain SMALA_RS21215 e2841c4405b3469a7801018d8b516bf3 1375 Gene3D G3DSA:1.25.40.10 101 272 1.3E-24 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS21215 e2841c4405b3469a7801018d8b516bf3 1375 SUPERFAMILY SSF52540 351 624 3.04E-21 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS21215 e2841c4405b3469a7801018d8b516bf3 1375 Gene3D G3DSA:1.10.10.10 4 100 3.1E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS21215 e2841c4405b3469a7801018d8b516bf3 1375 Gene3D G3DSA:3.40.50.300 346 506 2.1E-13 T 29-03-2018 SMALA_RS21215 e2841c4405b3469a7801018d8b516bf3 1375 SMART SM01043 99 241 2.7E-48 T 29-03-2018 IPR005158 Bacterial transcriptional activator domain SMALA_RS21215 e2841c4405b3469a7801018d8b516bf3 1375 SUPERFAMILY SSF48452 96 252 2.09E-31 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS21215 e2841c4405b3469a7801018d8b516bf3 1375 SUPERFAMILY SSF48452 1046 1159 3.54E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS21215 e2841c4405b3469a7801018d8b516bf3 1375 Gene3D G3DSA:1.25.40.10 816 1333 4.1E-13 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS21215 e2841c4405b3469a7801018d8b516bf3 1375 PRINTS PR00364 Disease resistance protein signature 379 394 6.5E-5 T 29-03-2018 SMALA_RS21215 e2841c4405b3469a7801018d8b516bf3 1375 PRINTS PR00364 Disease resistance protein signature 462 476 6.5E-5 T 29-03-2018 SMALA_RS21215 e2841c4405b3469a7801018d8b516bf3 1375 PRINTS PR00364 Disease resistance protein signature 558 572 6.5E-5 T 29-03-2018 SMALA_RS21215 e2841c4405b3469a7801018d8b516bf3 1375 SMART SM00862 16 90 3.4E-7 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS29185 1b1b1acf8944ff409618a0bf37e01c1e 217 Gene3D G3DSA:3.40.50.2300 1 119 3.1E-30 T 29-03-2018 SMALA_RS29185 1b1b1acf8944ff409618a0bf37e01c1e 217 SUPERFAMILY SSF52172 2 172 1.29E-34 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS29185 1b1b1acf8944ff409618a0bf37e01c1e 217 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 217 7.9E-23 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS29185 1b1b1acf8944ff409618a0bf37e01c1e 217 Pfam PF00072 Response regulator receiver domain 3 113 2.5E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS29185 1b1b1acf8944ff409618a0bf37e01c1e 217 Gene3D G3DSA:1.10.10.10 120 217 3.1E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS29185 1b1b1acf8944ff409618a0bf37e01c1e 217 SMART SM00448 1 112 6.1E-33 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS29185 1b1b1acf8944ff409618a0bf37e01c1e 217 SMART SM00862 145 217 4.1E-22 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS33210 6f6a1bcac11ca76491288a3397ca8172 467 Pfam PF01839 FG-GAP repeat 325 363 9.7E-10 T 29-03-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 SMALA_RS33210 6f6a1bcac11ca76491288a3397ca8172 467 SUPERFAMILY SSF69318 13 424 5.43E-55 T 29-03-2018 SMALA_RS33210 6f6a1bcac11ca76491288a3397ca8172 467 SMART SM00191 6 63 14.0 T 29-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMALA_RS33210 6f6a1bcac11ca76491288a3397ca8172 467 SMART SM00191 395 449 1.6E-4 T 29-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMALA_RS33210 6f6a1bcac11ca76491288a3397ca8172 467 SMART SM00191 75 133 8.9E-5 T 29-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMALA_RS33210 6f6a1bcac11ca76491288a3397ca8172 467 SMART SM00191 239 309 44.0 T 29-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMALA_RS33210 6f6a1bcac11ca76491288a3397ca8172 467 SMART SM00191 321 379 1.1E-7 T 29-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 SMALA_RS33210 6f6a1bcac11ca76491288a3397ca8172 467 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 17 97 8.0E-8 T 29-03-2018 SMALA_RS33210 6f6a1bcac11ca76491288a3397ca8172 467 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 197 262 1.6E-6 T 29-03-2018 SMALA_RS33210 6f6a1bcac11ca76491288a3397ca8172 467 Gene3D G3DSA:2.130.10.130 330 466 2.2E-19 T 29-03-2018 SMALA_RS33210 6f6a1bcac11ca76491288a3397ca8172 467 Gene3D G3DSA:2.60.40.680 169 224 0.11 T 29-03-2018 SMALA_RS33210 6f6a1bcac11ca76491288a3397ca8172 467 Gene3D G3DSA:2.60.40.680 225 329 2.8E-16 T 29-03-2018 SMALA_RS33210 6f6a1bcac11ca76491288a3397ca8172 467 Gene3D G3DSA:2.60.40.680 97 168 3.9E-5 T 29-03-2018 SMALA_RS33210 6f6a1bcac11ca76491288a3397ca8172 467 Gene3D G3DSA:2.60.40.680 4 96 1.5E-18 T 29-03-2018 SMALA_RS30605 cada146c0acadae81493c277b6a31c15 217 Pfam PF01081 KDPG and KHG aldolase 13 188 6.3E-44 T 29-03-2018 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 SMALA_RS30605 cada146c0acadae81493c277b6a31c15 217 ProSitePatterns PS00160 KDPG and KHG aldolases Schiff-base forming residue. 127 140 - T 29-03-2018 IPR031338 KDPG/KHG aldolase, active site 2 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 SMALA_RS30605 cada146c0acadae81493c277b6a31c15 217 SUPERFAMILY SSF51569 5 198 2.01E-58 T 29-03-2018 SMALA_RS30605 cada146c0acadae81493c277b6a31c15 217 Gene3D G3DSA:3.20.20.70 4 208 5.7E-37 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS30605 cada146c0acadae81493c277b6a31c15 217 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 12 188 1.3E-52 T 29-03-2018 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 SMALA_RS00565 745db81dd3c3dddaff5fb2259cdb5f24 230 Gene3D G3DSA:3.30.420.10 1 149 4.6E-39 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SMALA_RS00565 745db81dd3c3dddaff5fb2259cdb5f24 230 Pfam PF00075 RNase H 4 145 4.2E-28 T 29-03-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 SMALA_RS00565 745db81dd3c3dddaff5fb2259cdb5f24 230 SUPERFAMILY SSF53098 4 148 9.23E-38 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SMALA_RS00565 745db81dd3c3dddaff5fb2259cdb5f24 230 Hamap MF_00042 Ribonuclease H [rnhA]. 2 154 31.423 T 29-03-2018 IPR022892 Ribonuclease HI GO:0004523 SMALA_RS22010 72cee193d0f1fe8fd3d43b1d048fa151 174 SUPERFAMILY SSF55729 12 173 3.6E-29 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS22010 72cee193d0f1fe8fd3d43b1d048fa151 174 Gene3D G3DSA:3.40.630.30 4 174 9.5E-35 T 29-03-2018 SMALA_RS22010 72cee193d0f1fe8fd3d43b1d048fa151 174 Pfam PF00583 Acetyltransferase (GNAT) family 61 146 5.6E-14 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SMALA_RS00080 72cee193d0f1fe8fd3d43b1d048fa151 174 SUPERFAMILY SSF55729 12 173 3.6E-29 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS00080 72cee193d0f1fe8fd3d43b1d048fa151 174 Gene3D G3DSA:3.40.630.30 4 174 9.5E-35 T 29-03-2018 SMALA_RS00080 72cee193d0f1fe8fd3d43b1d048fa151 174 Pfam PF00583 Acetyltransferase (GNAT) family 61 146 5.6E-14 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SMALA_RS08715 4ab10b63c82e19f9922a28ae1d6a3ece 208 SUPERFAMILY SSF55811 9 183 1.29E-41 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMALA_RS08715 4ab10b63c82e19f9922a28ae1d6a3ece 208 Pfam PF00293 NUDIX domain 48 163 1.2E-15 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SMALA_RS08715 4ab10b63c82e19f9922a28ae1d6a3ece 208 Gene3D G3DSA:3.90.79.10 1 189 1.1E-34 T 29-03-2018 SMALA_RS19205 f3d6eb27a739219efc415aa4c3103586 335 SUPERFAMILY SSF50249 201 322 1.42E-33 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMALA_RS19205 f3d6eb27a739219efc415aa4c3103586 335 Gene3D G3DSA:2.40.50.140 256 323 1.2E-19 T 29-03-2018 SMALA_RS19205 f3d6eb27a739219efc415aa4c3103586 335 SUPERFAMILY SSF54637 35 170 4.71E-12 T 29-03-2018 IPR029069 HotDog domain SMALA_RS19205 f3d6eb27a739219efc415aa4c3103586 335 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 255 315 2.5E-22 T 29-03-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal SMALA_RS19205 f3d6eb27a739219efc415aa4c3103586 335 Gene3D G3DSA:3.10.129.10 13 187 9.4E-28 T 29-03-2018 SMALA_RS19205 f3d6eb27a739219efc415aa4c3103586 335 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 216 252 9.4E-7 T 29-03-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal SMALA_RS19205 f3d6eb27a739219efc415aa4c3103586 335 Pfam PF13452 N-terminal half of MaoC dehydratase 30 152 6.5E-11 T 29-03-2018 SMALA_RS28925 e6cafa2bc9243ecc155b614cdcd6058d 501 SUPERFAMILY SSF63737 27 215 1.31E-34 T 29-03-2018 SMALA_RS28925 e6cafa2bc9243ecc155b614cdcd6058d 501 Gene3D G3DSA:1.10.390.10 300 456 1.2E-37 T 29-03-2018 SMALA_RS28925 e6cafa2bc9243ecc155b614cdcd6058d 501 Pfam PF01433 Peptidase family M1 domain 300 452 2.2E-24 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMALA_RS28925 e6cafa2bc9243ecc155b614cdcd6058d 501 Gene3D G3DSA:2.60.40.1730 37 216 2.1E-36 T 29-03-2018 SMALA_RS28925 e6cafa2bc9243ecc155b614cdcd6058d 501 SUPERFAMILY SSF55486 224 460 6.59E-51 T 29-03-2018 SMALA_RS28925 e6cafa2bc9243ecc155b614cdcd6058d 501 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 326 338 7.1E-12 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMALA_RS28925 e6cafa2bc9243ecc155b614cdcd6058d 501 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 152 167 7.1E-12 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMALA_RS28925 e6cafa2bc9243ecc155b614cdcd6058d 501 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 307 322 7.1E-12 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMALA_RS03770 ab8d64b7a115013d016d2a36a39f0a62 138 TIGRFAM TIGR02364 dha_pts: dihydroxyacetone kinase, phosphotransfer subunit 10 132 2.0E-29 T 29-03-2018 IPR012844 Dihydroxyacetone kinase phosphotransferase subunit, N-terminal domain SMALA_RS03770 ab8d64b7a115013d016d2a36a39f0a62 138 SUPERFAMILY SSF53062 10 135 2.09E-29 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 SMALA_RS03770 ab8d64b7a115013d016d2a36a39f0a62 138 Gene3D G3DSA:3.40.50.510 5 138 2.1E-33 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 SMALA_RS03770 ab8d64b7a115013d016d2a36a39f0a62 138 Pfam PF03610 PTS system fructose IIA component 11 125 7.7E-26 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 SMALA_RS08985 1b75c6fa160a6b9b912d5312ebf84201 265 SMART SM00530 12 67 9.1E-11 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS08985 1b75c6fa160a6b9b912d5312ebf84201 265 SUPERFAMILY SSF47413 6 61 2.68E-11 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS08985 1b75c6fa160a6b9b912d5312ebf84201 265 Pfam PF13560 Helix-turn-helix domain 9 68 1.5E-15 T 29-03-2018 SMALA_RS08985 1b75c6fa160a6b9b912d5312ebf84201 265 Gene3D G3DSA:1.10.3100.10 4 141 8.5E-15 T 29-03-2018 IPR027910 YdiL-like domain SMALA_RS07755 047daabf3ddf5b03c9aad6967141f60a 140 Pfam PF13581 Histidine kinase-like ATPase domain 14 114 5.3E-14 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS07755 047daabf3ddf5b03c9aad6967141f60a 140 Gene3D G3DSA:3.30.565.10 3 140 1.3E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS07755 047daabf3ddf5b03c9aad6967141f60a 140 SUPERFAMILY SSF55874 8 135 1.68E-9 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS10065 b001d11a61d34b23fb74873498aa7793 197 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 32 176 1.5E-61 T 29-03-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 SMALA_RS10065 b001d11a61d34b23fb74873498aa7793 197 SUPERFAMILY SSF54211 88 181 4.55E-30 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SMALA_RS10065 b001d11a61d34b23fb74873498aa7793 197 Gene3D G3DSA:3.30.230.40 91 197 2.7E-31 T 29-03-2018 SMALA_RS10065 b001d11a61d34b23fb74873498aa7793 197 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 158 170 - T 29-03-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 SMALA_RS10065 b001d11a61d34b23fb74873498aa7793 197 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 3 197 41.041 T 29-03-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 SMALA_RS10065 b001d11a61d34b23fb74873498aa7793 197 Gene3D G3DSA:3.30.230.40 1 89 4.9E-33 T 29-03-2018 SMALA_RS10065 b001d11a61d34b23fb74873498aa7793 197 SUPERFAMILY SSF54211 3 86 2.78E-32 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SMALA_RS10065 b001d11a61d34b23fb74873498aa7793 197 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 62 75 - T 29-03-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 SMALA_RS18565 5564bcad3b9e521b43ec0557203058ca 369 SUPERFAMILY SSF52540 132 342 1.05E-25 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS18565 5564bcad3b9e521b43ec0557203058ca 369 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 135 340 1.0E-6 T 29-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain SMALA_RS18565 5564bcad3b9e521b43ec0557203058ca 369 Gene3D G3DSA:3.40.50.300 132 363 1.7E-29 T 29-03-2018 SMALA_RS18565 5564bcad3b9e521b43ec0557203058ca 369 TIGRFAM TIGR03815 CpaE_hom_Actino: helicase/secretion neighborhood CpaE-like protein 23 356 3.1E-107 T 29-03-2018 IPR022521 Conserved hypothetical protein CHP03815, CpaE-like SMALA_RS08655 bb25fff72ac4d122be17b3ea982ab651 487 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 276 291 9.8E-6 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 SMALA_RS08655 bb25fff72ac4d122be17b3ea982ab651 487 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 227 247 9.8E-6 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 SMALA_RS08655 bb25fff72ac4d122be17b3ea982ab651 487 PIRSF PIRSF006485 48 486 9.6E-158 T 29-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 SMALA_RS08655 bb25fff72ac4d122be17b3ea982ab651 487 Gene3D G3DSA:3.40.50.300 272 399 8.5E-20 T 29-03-2018 SMALA_RS08655 bb25fff72ac4d122be17b3ea982ab651 487 Pfam PF01926 50S ribosome-binding GTPase 226 344 1.8E-21 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 SMALA_RS08655 bb25fff72ac4d122be17b3ea982ab651 487 Pfam PF01926 50S ribosome-binding GTPase 52 166 1.4E-24 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 SMALA_RS08655 bb25fff72ac4d122be17b3ea982ab651 487 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 225 391 1.9E-21 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 SMALA_RS08655 bb25fff72ac4d122be17b3ea982ab651 487 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 52 171 2.5E-23 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 SMALA_RS08655 bb25fff72ac4d122be17b3ea982ab651 487 Hamap MF_00195 GTPase Der [der]. 49 481 35.674 T 29-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 SMALA_RS08655 bb25fff72ac4d122be17b3ea982ab651 487 SUPERFAMILY SSF52540 184 481 1.24E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS08655 bb25fff72ac4d122be17b3ea982ab651 487 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 400 478 2.5E-24 T 29-03-2018 IPR032859 GTPase Der, C-terminal KH-domain-like SMALA_RS08655 bb25fff72ac4d122be17b3ea982ab651 487 Gene3D G3DSA:3.40.50.300 117 271 2.6E-31 T 29-03-2018 SMALA_RS08655 bb25fff72ac4d122be17b3ea982ab651 487 Gene3D G3DSA:3.30.300.20 400 479 9.2E-28 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta SMALA_RS08655 bb25fff72ac4d122be17b3ea982ab651 487 Gene3D G3DSA:1.20.120.430 7 116 1.3E-17 T 29-03-2018 SMALA_RS08655 bb25fff72ac4d122be17b3ea982ab651 487 SUPERFAMILY SSF52540 51 214 7.68E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS08655 bb25fff72ac4d122be17b3ea982ab651 487 SMART SM00382 223 366 0.0023 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS08655 bb25fff72ac4d122be17b3ea982ab651 487 SMART SM00382 48 184 0.13 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS08655 bb25fff72ac4d122be17b3ea982ab651 487 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 50 478 2.9E-157 T 29-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 SMALA_RS03775 8f382f9cc7d8a34eb3c3a3f12eeb11c8 359 Gene3D G3DSA:1.10.600.10 10 359 2.2E-91 T 29-03-2018 IPR008949 Isoprenoid synthase domain SMALA_RS03775 8f382f9cc7d8a34eb3c3a3f12eeb11c8 359 SUPERFAMILY SSF48576 33 357 3.04E-78 T 29-03-2018 IPR008949 Isoprenoid synthase domain SMALA_RS03775 8f382f9cc7d8a34eb3c3a3f12eeb11c8 359 Pfam PF00348 Polyprenyl synthetase 42 307 4.1E-59 T 29-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 SMALA_RS03775 8f382f9cc7d8a34eb3c3a3f12eeb11c8 359 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 93 107 - T 29-03-2018 IPR033749 Polyprenyl synthetase, conserved site SMALA_RS03775 8f382f9cc7d8a34eb3c3a3f12eeb11c8 359 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 237 249 - T 29-03-2018 IPR033749 Polyprenyl synthetase, conserved site SMALA_RS24175 7af2bc70420d1da829224a7381670092 602 Gene3D G3DSA:3.30.1180.20 183 335 1.5E-39 T 29-03-2018 SMALA_RS24175 7af2bc70420d1da829224a7381670092 602 SUPERFAMILY SSF82549 11 333 1.39E-100 T 29-03-2018 SMALA_RS24175 7af2bc70420d1da829224a7381670092 602 SMART SM01120 402 578 7.7E-58 T 29-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 SMALA_RS24175 7af2bc70420d1da829224a7381670092 602 Pfam PF02733 Dak1 domain 17 330 3.0E-103 T 29-03-2018 IPR004006 DhaK domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 SMALA_RS24175 7af2bc70420d1da829224a7381670092 602 Pfam PF02734 DAK2 domain 403 576 4.6E-45 T 29-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 SMALA_RS24175 7af2bc70420d1da829224a7381670092 602 Gene3D G3DSA:3.40.50.10440 11 182 3.1E-52 T 29-03-2018 SMALA_RS24175 7af2bc70420d1da829224a7381670092 602 SUPERFAMILY SSF101473 376 579 2.35E-43 T 29-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 SMALA_RS17020 1deaac8e1077f532de7ebfd4968ab3cd 265 Gene3D G3DSA:3.40.225.10 28 257 3.5E-64 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal SMALA_RS17020 1deaac8e1077f532de7ebfd4968ab3cd 265 SUPERFAMILY SSF53639 29 247 4.32E-62 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal SMALA_RS17020 1deaac8e1077f532de7ebfd4968ab3cd 265 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 37 216 2.0E-45 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal SMALA_RS17020 1deaac8e1077f532de7ebfd4968ab3cd 265 SMART SM01007 36 216 2.0E-50 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal SMALA_RS02130 9d22e343e3aaede01e24531633c17e2d 186 SUPERFAMILY SSF55729 9 175 2.57E-36 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS02130 9d22e343e3aaede01e24531633c17e2d 186 Gene3D G3DSA:3.40.630.30 5 183 2.1E-27 T 29-03-2018 SMALA_RS02130 9d22e343e3aaede01e24531633c17e2d 186 Pfam PF13302 Acetyltransferase (GNAT) domain 12 151 1.7E-18 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SMALA_RS38355 0cd51fc942ec16430f3f6583e3562f6c 413 Gene3D G3DSA:3.30.390.10 4 100 1.0E-28 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMALA_RS38355 0cd51fc942ec16430f3f6583e3562f6c 413 SMART SM00922 128 268 2.4E-20 T 29-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal SMALA_RS38355 0cd51fc942ec16430f3f6583e3562f6c 413 SUPERFAMILY SSF54826 4 112 1.92E-31 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMALA_RS38355 0cd51fc942ec16430f3f6583e3562f6c 413 SUPERFAMILY SSF51604 98 397 3.8E-72 T 29-03-2018 IPR029065 Enolase C-terminal domain-like SMALA_RS38355 0cd51fc942ec16430f3f6583e3562f6c 413 Gene3D G3DSA:3.20.20.120 101 386 1.4E-62 T 29-03-2018 IPR029065 Enolase C-terminal domain-like SMALA_RS38355 0cd51fc942ec16430f3f6583e3562f6c 413 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 85 110 - T 29-03-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 SMALA_RS38355 0cd51fc942ec16430f3f6583e3562f6c 413 Pfam PF13378 Enolase C-terminal domain-like 197 389 1.4E-43 T 29-03-2018 IPR029065 Enolase C-terminal domain-like SMALA_RS38355 0cd51fc942ec16430f3f6583e3562f6c 413 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 14 110 9.0E-32 T 29-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain SMALA_RS02425 546a0db612df7e376903fcd0b2cb3e88 152 SMART SM00347 20 123 2.1E-16 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS02425 546a0db612df7e376903fcd0b2cb3e88 152 Gene3D G3DSA:1.10.10.10 1 150 1.4E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS02425 546a0db612df7e376903fcd0b2cb3e88 152 SUPERFAMILY SSF46785 17 137 2.36E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS02425 546a0db612df7e376903fcd0b2cb3e88 152 Pfam PF01047 MarR family 32 87 9.0E-12 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS02425 546a0db612df7e376903fcd0b2cb3e88 152 PRINTS PR00598 Bacterial regulatory protein MarR family signature 113 133 3.3E-7 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS02425 546a0db612df7e376903fcd0b2cb3e88 152 PRINTS PR00598 Bacterial regulatory protein MarR family signature 83 99 3.3E-7 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS02425 546a0db612df7e376903fcd0b2cb3e88 152 PRINTS PR00598 Bacterial regulatory protein MarR family signature 64 79 3.3E-7 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS37790 6bdf305bfbddd8db8594af2c8063de97 700 SMART SM00382 474 606 1.2E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS37790 6bdf305bfbddd8db8594af2c8063de97 700 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 479 604 2.0E-25 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 SMALA_RS37790 6bdf305bfbddd8db8594af2c8063de97 700 SUPERFAMILY SSF52540 431 669 8.44E-39 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS37790 6bdf305bfbddd8db8594af2c8063de97 700 Gene3D G3DSA:3.40.50.300 426 616 4.6E-27 T 29-03-2018 SMALA_RS20665 3ffb2043169f1f23b51955211784d71c 157 ProSitePatterns PS00552 MerR-type HTH domain signature. 31 53 - T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS20665 3ffb2043169f1f23b51955211784d71c 157 Gene3D G3DSA:1.20.5.730 84 144 9.0E-4 T 29-03-2018 SMALA_RS20665 3ffb2043169f1f23b51955211784d71c 157 SUPERFAMILY SSF46955 28 123 2.01E-19 T 29-03-2018 IPR009061 Putative DNA-binding domain SMALA_RS20665 3ffb2043169f1f23b51955211784d71c 157 Gene3D G3DSA:1.10.1660.10 24 83 4.8E-20 T 29-03-2018 SMALA_RS20665 3ffb2043169f1f23b51955211784d71c 157 SMART SM00422 28 97 5.5E-26 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS20665 3ffb2043169f1f23b51955211784d71c 157 Pfam PF13411 MerR HTH family regulatory protein 28 95 1.4E-16 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS36025 c81953bce83b06d9fe423eccf1de855c 328 Pfam PF00248 Aldo/keto reductase family 15 312 5.1E-71 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS36025 c81953bce83b06d9fe423eccf1de855c 328 SUPERFAMILY SSF51430 1 315 2.62E-95 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS36025 c81953bce83b06d9fe423eccf1de855c 328 Gene3D G3DSA:3.20.20.100 1 317 3.2E-89 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS36025 c81953bce83b06d9fe423eccf1de855c 328 PRINTS PR00069 Aldo-keto reductase signature 39 63 7.5E-5 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMALA_RS36025 c81953bce83b06d9fe423eccf1de855c 328 PRINTS PR00069 Aldo-keto reductase signature 141 158 7.5E-5 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMALA_RS31570 43067efbdbd0023de5dc17219b04a74f 274 Gene3D G3DSA:1.20.5.1230 43 242 2.1E-13 T 29-03-2018 SMALA_RS04940 4a1853fef63e206786507bacf5cef669 346 Pfam PF01497 Periplasmic binding protein 61 317 1.7E-36 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 SMALA_RS04940 4a1853fef63e206786507bacf5cef669 346 Gene3D G3DSA:3.40.50.1980 178 341 1.0E-34 T 29-03-2018 SMALA_RS04940 4a1853fef63e206786507bacf5cef669 346 Gene3D G3DSA:3.40.50.1980 33 177 3.4E-30 T 29-03-2018 SMALA_RS04940 4a1853fef63e206786507bacf5cef669 346 SUPERFAMILY SSF53807 57 339 7.85E-42 T 29-03-2018 SMALA_RS36215 f99feb2b4b2c402bae521584a4856646 461 Pfam PF00672 HAMP domain 149 199 4.8E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMALA_RS36215 f99feb2b4b2c402bae521584a4856646 461 SUPERFAMILY SSF55874 331 440 9.3E-23 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS36215 f99feb2b4b2c402bae521584a4856646 461 Gene3D G3DSA:3.30.565.10 245 440 2.7E-30 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS36215 f99feb2b4b2c402bae521584a4856646 461 SMART SM00388 203 261 1.3E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS36215 f99feb2b4b2c402bae521584a4856646 461 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 337 441 9.6E-13 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS36215 f99feb2b4b2c402bae521584a4856646 461 Pfam PF00512 His Kinase A (phospho-acceptor) domain 205 261 1.9E-10 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS36215 f99feb2b4b2c402bae521584a4856646 461 SUPERFAMILY SSF158472 150 199 6.54E-6 T 29-03-2018 SMALA_RS36215 f99feb2b4b2c402bae521584a4856646 461 SUPERFAMILY SSF47384 190 261 2.35E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS36215 f99feb2b4b2c402bae521584a4856646 461 Gene3D G3DSA:1.10.287.130 193 244 3.2E-10 T 29-03-2018 SMALA_RS36215 f99feb2b4b2c402bae521584a4856646 461 SMART SM00304 148 202 1.1E-8 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMALA_RS36215 f99feb2b4b2c402bae521584a4856646 461 SMART SM00387 337 442 1.2E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS35365 8632196910292c7cc6493f3e7bdc33eb 480 Pfam PF07690 Major Facilitator Superfamily 15 408 2.3E-43 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS35365 8632196910292c7cc6493f3e7bdc33eb 480 Gene3D G3DSA:1.20.1250.20 6 190 3.5E-31 T 29-03-2018 SMALA_RS35365 8632196910292c7cc6493f3e7bdc33eb 480 Gene3D G3DSA:1.20.1250.20 255 471 1.1E-26 T 29-03-2018 SMALA_RS35365 8632196910292c7cc6493f3e7bdc33eb 480 SUPERFAMILY SSF103473 6 190 4.58E-41 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS35365 8632196910292c7cc6493f3e7bdc33eb 480 SUPERFAMILY SSF103473 197 462 8.24E-25 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS34235 44decbb778a623b520b165852189b3d7 303 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 296 5.4E-19 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS34235 44decbb778a623b520b165852189b3d7 303 Gene3D G3DSA:1.10.3720.10 26 290 3.0E-41 T 29-03-2018 SMALA_RS34235 44decbb778a623b520b165852189b3d7 303 SUPERFAMILY SSF161098 34 303 3.66E-71 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS14960 019071e5391a64c89e38e600d8607cc5 317 Pfam PF00005 ABC transporter 34 177 3.7E-24 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS14960 019071e5391a64c89e38e600d8607cc5 317 Gene3D G3DSA:3.40.50.300 1 270 1.2E-55 T 29-03-2018 SMALA_RS14960 019071e5391a64c89e38e600d8607cc5 317 SMART SM00382 42 227 1.1E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS14960 019071e5391a64c89e38e600d8607cc5 317 SUPERFAMILY SSF52540 28 244 2.36E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS22115 19cd47df2d0bcd0a3d093205fa4811b4 246 TIGRFAM TIGR01961 NuoC_fam: NADH (or F420H2) dehydrogenase, subunit C 103 225 3.0E-43 T 29-03-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS22115 19cd47df2d0bcd0a3d093205fa4811b4 246 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 154 209 5.0E-24 T 29-03-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS22115 19cd47df2d0bcd0a3d093205fa4811b4 246 SUPERFAMILY SSF143243 90 242 2.22E-46 T 29-03-2018 SMALA_RS22115 19cd47df2d0bcd0a3d093205fa4811b4 246 Hamap MF_01357 NAD(P)H-quinone oxidoreductase subunit J, chloroplastic [ndhJ]. 77 234 28.17 T 29-03-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS22115 19cd47df2d0bcd0a3d093205fa4811b4 246 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 105 226 1.4E-40 T 29-03-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS13485 3667fcc85b087b18496f2724a4cb6305 375 Pfam PF00498 FHA domain 287 365 1.4E-13 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 SMALA_RS13485 3667fcc85b087b18496f2724a4cb6305 375 Gene3D G3DSA:2.60.200.20 154 374 8.5E-31 T 29-03-2018 SMALA_RS13485 3667fcc85b087b18496f2724a4cb6305 375 SMART SM00240 286 348 0.0021 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 SMALA_RS13485 3667fcc85b087b18496f2724a4cb6305 375 SUPERFAMILY SSF49879 270 370 5.93E-21 T 29-03-2018 IPR008984 SMAD/FHA domain GO:0005515 SMALA_RS06860 57e683ed7eaafbd8fbeabcdde0627b2a 356 SUPERFAMILY SSF56796 6 332 9.55E-89 T 29-03-2018 SMALA_RS06860 57e683ed7eaafbd8fbeabcdde0627b2a 356 PIRSF PIRSF001455 16 337 8.6E-80 T 29-03-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 SMALA_RS06860 57e683ed7eaafbd8fbeabcdde0627b2a 356 Pfam PF01761 3-dehydroquinate synthase 61 302 2.8E-79 T 29-03-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 SMALA_RS06860 57e683ed7eaafbd8fbeabcdde0627b2a 356 Gene3D G3DSA:3.40.50.1970 8 164 2.4E-38 T 29-03-2018 SMALA_RS06860 57e683ed7eaafbd8fbeabcdde0627b2a 356 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 3 333 30.851 T 29-03-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 SMALA_RS06860 57e683ed7eaafbd8fbeabcdde0627b2a 356 Gene3D G3DSA:1.20.1090.10 165 338 4.6E-40 T 29-03-2018 SMALA_RS22530 d35654293dc2e94d70aeab4558b9f5eb 102 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 29-03-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMALA_RS22530 d35654293dc2e94d70aeab4558b9f5eb 102 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 27.897 T 29-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMALA_RS22530 d35654293dc2e94d70aeab4558b9f5eb 102 SUPERFAMILY SSF54999 5 102 1.02E-38 T 29-03-2018 IPR027486 Ribosomal protein S10 domain SMALA_RS22530 d35654293dc2e94d70aeab4558b9f5eb 102 Pfam PF00338 Ribosomal protein S10p/S20e 7 101 8.0E-37 T 29-03-2018 IPR027486 Ribosomal protein S10 domain SMALA_RS22530 d35654293dc2e94d70aeab4558b9f5eb 102 Gene3D G3DSA:3.30.70.600 4 102 1.0E-36 T 29-03-2018 IPR027486 Ribosomal protein S10 domain SMALA_RS22530 d35654293dc2e94d70aeab4558b9f5eb 102 SMART SM01403 7 101 3.5E-59 T 29-03-2018 IPR027486 Ribosomal protein S10 domain SMALA_RS22530 d35654293dc2e94d70aeab4558b9f5eb 102 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 1.1E-47 T 29-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMALA_RS22530 d35654293dc2e94d70aeab4558b9f5eb 102 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 4.6E-21 T 29-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMALA_RS22530 d35654293dc2e94d70aeab4558b9f5eb 102 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 4.6E-21 T 29-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMALA_RS22530 d35654293dc2e94d70aeab4558b9f5eb 102 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 4.6E-21 T 29-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMALA_RS00395 1ca8d763fb367cfc6f74db59bbdaf7be 361 Gene3D G3DSA:3.40.50.970 26 220 2.2E-37 T 29-03-2018 SMALA_RS00395 1ca8d763fb367cfc6f74db59bbdaf7be 361 Gene3D G3DSA:3.40.50.920 222 361 1.5E-17 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMALA_RS00395 1ca8d763fb367cfc6f74db59bbdaf7be 361 Pfam PF02779 Transketolase, pyrimidine binding domain 34 203 1.8E-25 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain SMALA_RS00395 1ca8d763fb367cfc6f74db59bbdaf7be 361 SUPERFAMILY SSF52518 30 207 4.18E-39 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold SMALA_RS00395 1ca8d763fb367cfc6f74db59bbdaf7be 361 SMART SM00861 29 204 8.1E-23 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain SMALA_RS00395 1ca8d763fb367cfc6f74db59bbdaf7be 361 Pfam PF02780 Transketolase, C-terminal domain 235 352 8.6E-13 T 29-03-2018 IPR033248 Transketolase, C-terminal domain SMALA_RS00395 1ca8d763fb367cfc6f74db59bbdaf7be 361 SUPERFAMILY SSF52922 235 360 1.7E-18 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMALA_RS25750 d55f9eaa1b30dc2bbbc548349656c4d8 108 Pfam PF00037 4Fe-4S binding domain 34 55 1.3E-8 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain SMALA_RS25750 d55f9eaa1b30dc2bbbc548349656c4d8 108 SUPERFAMILY SSF54862 3 90 9.12E-22 T 29-03-2018 SMALA_RS25750 d55f9eaa1b30dc2bbbc548349656c4d8 108 Gene3D G3DSA:3.30.70.20 2 44 1.9E-11 T 29-03-2018 SMALA_RS25750 d55f9eaa1b30dc2bbbc548349656c4d8 108 Gene3D G3DSA:3.30.70.20 45 94 6.9E-9 T 29-03-2018 SMALA_RS25750 d55f9eaa1b30dc2bbbc548349656c4d8 108 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site SMALA_RS25750 d55f9eaa1b30dc2bbbc548349656c4d8 108 PRINTS PR00354 7Fe ferredoxin signature 19 29 6.0E-18 T 29-03-2018 IPR000813 7Fe ferredoxin GO:0009055 SMALA_RS25750 d55f9eaa1b30dc2bbbc548349656c4d8 108 PRINTS PR00354 7Fe ferredoxin signature 35 52 6.0E-18 T 29-03-2018 IPR000813 7Fe ferredoxin GO:0009055 SMALA_RS25750 d55f9eaa1b30dc2bbbc548349656c4d8 108 PRINTS PR00354 7Fe ferredoxin signature 9 19 6.0E-18 T 29-03-2018 IPR000813 7Fe ferredoxin GO:0009055 SMALA_RS23300 9211ab0797daabd7f2e859af083b5eb1 813 SUPERFAMILY SSF56112 149 411 1.82E-39 T 29-03-2018 IPR011009 Protein kinase-like domain SMALA_RS23300 9211ab0797daabd7f2e859af083b5eb1 813 Gene3D G3DSA:1.10.510.10 247 427 4.5E-17 T 29-03-2018 SMALA_RS23300 9211ab0797daabd7f2e859af083b5eb1 813 SUPERFAMILY SSF48452 508 637 2.9E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS23300 9211ab0797daabd7f2e859af083b5eb1 813 Pfam PF00069 Protein kinase domain 158 363 1.8E-27 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMALA_RS23300 9211ab0797daabd7f2e859af083b5eb1 813 Pfam PF16918 Protein kinase G tetratricopeptide repeat 772 811 1.1E-6 T 29-03-2018 IPR031636 Protein kinase G, tetratricopeptide repeat containing domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 SMALA_RS23300 9211ab0797daabd7f2e859af083b5eb1 813 Pfam PF16918 Protein kinase G tetratricopeptide repeat 423 719 4.2E-52 T 29-03-2018 IPR031636 Protein kinase G, tetratricopeptide repeat containing domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 SMALA_RS23300 9211ab0797daabd7f2e859af083b5eb1 813 Gene3D G3DSA:1.25.40.120 476 811 3.3E-13 T 29-03-2018 SMALA_RS23300 9211ab0797daabd7f2e859af083b5eb1 813 SMART SM00220 158 406 2.1E-12 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMALA_RS23300 9211ab0797daabd7f2e859af083b5eb1 813 Pfam PF16919 Protein kinase G rubredoxin domain 72 157 1.1E-10 T 29-03-2018 IPR031634 Protein kinase G, rubredoxin domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 SMALA_RS23300 9211ab0797daabd7f2e859af083b5eb1 813 Gene3D G3DSA:3.30.200.20 151 246 4.5E-17 T 29-03-2018 SMALA_RS33490 e98fff986d3a22699f82c31b9de27f2e 70 Gene3D G3DSA:3.90.820.10 3 69 2.3E-33 T 29-03-2018 SMALA_RS33490 e98fff986d3a22699f82c31b9de27f2e 70 Pfam PF03621 MbtH-like protein 4 53 3.4E-26 T 29-03-2018 IPR005153 MbtH-like protein SMALA_RS33490 e98fff986d3a22699f82c31b9de27f2e 70 SMART SM00923 4 54 1.0E-27 T 29-03-2018 IPR005153 MbtH-like protein SMALA_RS33490 e98fff986d3a22699f82c31b9de27f2e 70 SUPERFAMILY SSF160582 3 69 9.42E-30 T 29-03-2018 SMALA_RS39570 754a463d1ce8643af03b8cd3b1a4e60b 401 Pfam PF00175 Oxidoreductase NAD-binding domain 271 372 3.1E-12 T 29-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 SMALA_RS39570 754a463d1ce8643af03b8cd3b1a4e60b 401 Pfam PF00042 Globin 8 103 4.7E-5 T 29-03-2018 IPR000971 Globin GO:0020037 SMALA_RS39570 754a463d1ce8643af03b8cd3b1a4e60b 401 Gene3D G3DSA:3.40.50.80 261 398 1.2E-21 T 29-03-2018 SMALA_RS39570 754a463d1ce8643af03b8cd3b1a4e60b 401 Gene3D G3DSA:1.10.490.10 1 160 5.1E-33 T 29-03-2018 SMALA_RS39570 754a463d1ce8643af03b8cd3b1a4e60b 401 SUPERFAMILY SSF63380 154 259 7.35E-26 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 SMALA_RS39570 754a463d1ce8643af03b8cd3b1a4e60b 401 Gene3D G3DSA:2.40.30.10 161 260 7.9E-25 T 29-03-2018 SMALA_RS39570 754a463d1ce8643af03b8cd3b1a4e60b 401 SUPERFAMILY SSF52343 263 392 1.96E-31 T 29-03-2018 SMALA_RS39570 754a463d1ce8643af03b8cd3b1a4e60b 401 Pfam PF00970 Oxidoreductase FAD-binding domain 159 260 1.6E-6 T 29-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 SMALA_RS39570 754a463d1ce8643af03b8cd3b1a4e60b 401 SUPERFAMILY SSF46458 1 147 1.83E-29 T 29-03-2018 IPR009050 Globin-like SMALA_RS23050 aa3411c1786ee5c87dcec68c0514a46a 488 Gene3D G3DSA:3.40.605.10 1 273 6.9E-85 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS23050 aa3411c1786ee5c87dcec68c0514a46a 488 Pfam PF00171 Aldehyde dehydrogenase family 13 483 2.0E-154 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS23050 aa3411c1786ee5c87dcec68c0514a46a 488 Gene3D G3DSA:3.40.309.10 274 469 1.6E-65 T 29-03-2018 SMALA_RS23050 aa3411c1786ee5c87dcec68c0514a46a 488 SUPERFAMILY SSF53720 2 484 2.09E-149 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMALA_RS18830 f7a82a7559258813fd5ebeb611cd8575 397 Gene3D G3DSA:1.10.150.130 55 166 1.2E-21 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal SMALA_RS18830 f7a82a7559258813fd5ebeb611cd8575 397 Pfam PF00589 Phage integrase family 171 374 2.3E-20 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 SMALA_RS18830 f7a82a7559258813fd5ebeb611cd8575 397 Gene3D G3DSA:1.10.443.10 167 377 2.3E-43 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 SMALA_RS18830 f7a82a7559258813fd5ebeb611cd8575 397 SUPERFAMILY SSF56349 256 384 1.5E-62 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 SMALA_RS18830 f7a82a7559258813fd5ebeb611cd8575 397 SUPERFAMILY SSF56349 59 220 1.5E-62 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 SMALA_RS18830 f7a82a7559258813fd5ebeb611cd8575 397 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 60 117 8.0E-8 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 SMALA_RS32370 cf8e698c74bff72263dd4db9129594e6 273 PRINTS PR01837 MgtC/SapB protein signature 37 56 3.2E-41 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 SMALA_RS32370 cf8e698c74bff72263dd4db9129594e6 273 PRINTS PR01837 MgtC/SapB protein signature 117 141 3.2E-41 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 SMALA_RS32370 cf8e698c74bff72263dd4db9129594e6 273 PRINTS PR01837 MgtC/SapB protein signature 56 74 3.2E-41 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 SMALA_RS32370 cf8e698c74bff72263dd4db9129594e6 273 PRINTS PR01837 MgtC/SapB protein signature 90 112 3.2E-41 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 SMALA_RS32370 cf8e698c74bff72263dd4db9129594e6 273 Pfam PF02308 MgtC family 34 157 2.6E-36 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 SMALA_RS03715 117ff0c5de3825d0310eaa7aa71ef48a 518 SUPERFAMILY SSF51905 1 323 4.32E-33 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS03715 117ff0c5de3825d0310eaa7aa71ef48a 518 Pfam PF01593 Flavin containing amine oxidoreductase 18 302 4.4E-12 T 29-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 SMALA_RS03715 117ff0c5de3825d0310eaa7aa71ef48a 518 Gene3D G3DSA:3.50.50.60 1 486 6.9E-31 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS10800 df4f4085cbcd2824682cf895fe5ded28 452 Gene3D G3DSA:1.20.1250.20 229 436 3.3E-23 T 29-03-2018 SMALA_RS10800 df4f4085cbcd2824682cf895fe5ded28 452 Gene3D G3DSA:1.20.1250.20 18 228 1.3E-22 T 29-03-2018 SMALA_RS10800 df4f4085cbcd2824682cf895fe5ded28 452 Pfam PF00083 Sugar (and other) transporter 21 239 1.0E-19 T 29-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 SMALA_RS10800 df4f4085cbcd2824682cf895fe5ded28 452 SUPERFAMILY SSF103473 8 428 1.96E-61 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS10800 df4f4085cbcd2824682cf895fe5ded28 452 Pfam PF07690 Major Facilitator Superfamily 263 440 1.7E-12 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS06710 0154a3e356ee0741bcb6f1b105fc06e3 480 Gene3D G3DSA:3.40.50.980 122 299 1.9E-21 T 29-03-2018 SMALA_RS06710 0154a3e356ee0741bcb6f1b105fc06e3 480 Pfam PF14535 AMP-binding enzyme C-terminal domain 371 464 1.7E-18 T 29-03-2018 IPR028154 AMP-dependent ligase, C-terminal SMALA_RS06710 0154a3e356ee0741bcb6f1b105fc06e3 480 Pfam PF00501 AMP-binding enzyme 109 316 6.5E-11 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS06710 0154a3e356ee0741bcb6f1b105fc06e3 480 SUPERFAMILY SSF56801 62 428 2.62E-41 T 29-03-2018 SMALA_RS06710 0154a3e356ee0741bcb6f1b105fc06e3 480 Gene3D G3DSA:3.40.50.980 41 121 0.015 T 29-03-2018 SMALA_RS06710 0154a3e356ee0741bcb6f1b105fc06e3 480 Gene3D G3DSA:3.30.300.30 361 466 1.1E-7 T 29-03-2018 SMALA_RS32240 ee52c4c6a81fbac352f3d6e3e6c8f32f 249 Gene3D G3DSA:1.20.120.530 105 248 5.6E-24 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS32240 ee52c4c6a81fbac352f3d6e3e6c8f32f 249 Pfam PF07729 FCD domain 119 238 4.5E-19 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS32240 ee52c4c6a81fbac352f3d6e3e6c8f32f 249 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 65 81 5.0E-10 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS32240 ee52c4c6a81fbac352f3d6e3e6c8f32f 249 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 51 65 5.0E-10 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS32240 ee52c4c6a81fbac352f3d6e3e6c8f32f 249 SUPERFAMILY SSF48008 115 246 4.18E-22 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS32240 ee52c4c6a81fbac352f3d6e3e6c8f32f 249 Pfam PF00392 Bacterial regulatory proteins, gntR family 31 93 1.6E-12 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS32240 ee52c4c6a81fbac352f3d6e3e6c8f32f 249 SMART SM00345 32 93 8.0E-12 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS32240 ee52c4c6a81fbac352f3d6e3e6c8f32f 249 SMART SM00895 118 239 3.6E-18 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS32240 ee52c4c6a81fbac352f3d6e3e6c8f32f 249 Gene3D G3DSA:1.10.10.10 22 95 6.5E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS32240 ee52c4c6a81fbac352f3d6e3e6c8f32f 249 SUPERFAMILY SSF46785 24 97 3.18E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS00810 0e37a81c7ba050e04f450c36637980ca 562 Gene3D G3DSA:3.30.450.20 34 172 5.7E-22 T 29-03-2018 SMALA_RS00810 0e37a81c7ba050e04f450c36637980ca 562 SUPERFAMILY SSF55890 318 365 1.83E-7 T 29-03-2018 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 SMALA_RS00810 0e37a81c7ba050e04f450c36637980ca 562 Gene3D G3DSA:3.30.450.20 204 317 8.8E-9 T 29-03-2018 SMALA_RS00810 0e37a81c7ba050e04f450c36637980ca 562 SMART SM00387 413 545 7.3E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS00810 0e37a81c7ba050e04f450c36637980ca 562 SUPERFAMILY SSF103190 38 169 1.69E-29 T 29-03-2018 IPR029151 Periplasmic sensor domain-like SMALA_RS00810 0e37a81c7ba050e04f450c36637980ca 562 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 414 543 1.7E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS00810 0e37a81c7ba050e04f450c36637980ca 562 Pfam PF00989 PAS fold 216 253 1.2E-5 T 29-03-2018 IPR013767 PAS fold GO:0006355 SMALA_RS00810 0e37a81c7ba050e04f450c36637980ca 562 Gene3D G3DSA:1.10.287.130 318 373 2.5E-15 T 29-03-2018 SMALA_RS00810 0e37a81c7ba050e04f450c36637980ca 562 SUPERFAMILY SSF55874 385 542 7.33E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS00810 0e37a81c7ba050e04f450c36637980ca 562 PRINTS PR00344 Bacterial sensor protein C-terminal signature 454 468 9.4E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS00810 0e37a81c7ba050e04f450c36637980ca 562 PRINTS PR00344 Bacterial sensor protein C-terminal signature 505 523 9.4E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS00810 0e37a81c7ba050e04f450c36637980ca 562 PRINTS PR00344 Bacterial sensor protein C-terminal signature 529 542 9.4E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS00810 0e37a81c7ba050e04f450c36637980ca 562 Gene3D G3DSA:3.30.565.10 375 556 2.3E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS00810 0e37a81c7ba050e04f450c36637980ca 562 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 318 364 3.3E-7 T 29-03-2018 SMALA_RS00810 0e37a81c7ba050e04f450c36637980ca 562 SUPERFAMILY SSF55785 218 303 2.27E-6 T 29-03-2018 IPR000014 PAS domain SMALA_RS00810 0e37a81c7ba050e04f450c36637980ca 562 Pfam PF17203 Single cache domain 3 38 170 4.7E-22 T 29-03-2018 IPR033463 Single cache domain 3 SMALA_RS24620 9897dc5053431fc462d119eb788288c7 467 SUPERFAMILY SSF52540 69 402 1.73E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS24620 9897dc5053431fc462d119eb788288c7 467 Gene3D G3DSA:3.30.450.90 83 185 4.9E-35 T 29-03-2018 SMALA_RS24620 9897dc5053431fc462d119eb788288c7 467 Pfam PF00437 Type II/IV secretion system protein 89 364 2.5E-87 T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 SMALA_RS24620 9897dc5053431fc462d119eb788288c7 467 Gene3D G3DSA:3.40.50.300 186 388 1.2E-18 T 29-03-2018 SMALA_RS30925 df78ea0145491d3135c4c2649626f5e1 800 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 474 666 2.5E-50 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS30925 df78ea0145491d3135c4c2649626f5e1 800 Pfam PF13185 GAF domain 324 418 2.3E-7 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS30925 df78ea0145491d3135c4c2649626f5e1 800 SUPERFAMILY SSF55781 318 427 1.09E-12 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS30925 df78ea0145491d3135c4c2649626f5e1 800 Gene3D G3DSA:3.30.450.20 1 113 1.6E-8 T 29-03-2018 SMALA_RS30925 df78ea0145491d3135c4c2649626f5e1 800 SUPERFAMILY SSF55874 700 791 9.03E-7 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS30925 df78ea0145491d3135c4c2649626f5e1 800 Gene3D G3DSA:3.30.565.10 671 800 1.3E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS30925 df78ea0145491d3135c4c2649626f5e1 800 SUPERFAMILY SSF81606 461 667 1.83E-12 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS30925 df78ea0145491d3135c4c2649626f5e1 800 SUPERFAMILY SSF55785 1 60 1.06E-8 T 29-03-2018 IPR000014 PAS domain SMALA_RS30925 df78ea0145491d3135c4c2649626f5e1 800 SMART SM00331 445 666 4.5E-49 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS30925 df78ea0145491d3135c4c2649626f5e1 800 Pfam PF13581 Histidine kinase-like ATPase domain 680 788 4.5E-10 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS30925 df78ea0145491d3135c4c2649626f5e1 800 Gene3D G3DSA:3.30.450.40 191 426 9.0E-29 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS30925 df78ea0145491d3135c4c2649626f5e1 800 Gene3D G3DSA:3.60.40.10 427 669 1.5E-43 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS19510 97c843738511bcf408db6d5273381fd8 210 Pfam PF12710 haloacid dehalogenase-like hydrolase 6 170 8.6E-12 T 29-03-2018 SMALA_RS19510 97c843738511bcf408db6d5273381fd8 210 SUPERFAMILY SSF56784 2 201 2.03E-21 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS19510 97c843738511bcf408db6d5273381fd8 210 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 5 172 5.8E-18 T 29-03-2018 SMALA_RS19510 97c843738511bcf408db6d5273381fd8 210 Gene3D G3DSA:3.40.50.1000 1 198 4.2E-17 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS14845 156f234ccc4048a6fae8ccf70c233bcd 196 Gene3D G3DSA:2.60.120.260 33 196 4.2E-16 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS14845 156f234ccc4048a6fae8ccf70c233bcd 196 Pfam PF04862 Protein of unknown function (DUF642) 33 186 1.4E-28 T 29-03-2018 IPR006946 Domain of unknown function DUF642 SMALA_RS14845 156f234ccc4048a6fae8ccf70c233bcd 196 TIGRFAM TIGR04362 choice_anch_C: choice-of-anchor C domain 33 186 1.2E-48 T 29-03-2018 IPR027576 Choice-of-anchor C domain SMALA_RS34070 f91079e78233172837228df6d1e198bf 265 Gene3D G3DSA:3.40.50.150 2 264 9.6E-49 T 29-03-2018 SMALA_RS34070 f91079e78233172837228df6d1e198bf 265 SUPERFAMILY SSF53335 15 252 1.57E-42 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS34070 f91079e78233172837228df6d1e198bf 265 PIRSF PIRSF017393 2 264 1.2E-100 T 29-03-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type SMALA_RS34070 f91079e78233172837228df6d1e198bf 265 Pfam PF04672 S-adenosyl methyltransferase 8 263 1.9E-99 T 29-03-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type SMALA_RS34695 357193bc64f1dc331842ca29b4d68c5c 334 SUPERFAMILY SSF54631 205 333 9.22E-25 T 29-03-2018 SMALA_RS34695 357193bc64f1dc331842ca29b4d68c5c 334 Pfam PF01595 Domain of unknown function DUF21 8 199 4.6E-42 T 29-03-2018 IPR002550 Domain of unknown function DUF21 SMALA_RS34695 357193bc64f1dc331842ca29b4d68c5c 334 Pfam PF00571 CBS domain 225 271 1.1E-5 T 29-03-2018 IPR000644 CBS domain SMALA_RS34695 357193bc64f1dc331842ca29b4d68c5c 334 Pfam PF00571 CBS domain 284 333 3.3E-7 T 29-03-2018 IPR000644 CBS domain SMALA_RS34695 357193bc64f1dc331842ca29b4d68c5c 334 SMART SM00116 285 333 0.013 T 29-03-2018 IPR000644 CBS domain SMALA_RS34695 357193bc64f1dc331842ca29b4d68c5c 334 SMART SM00116 225 273 0.2 T 29-03-2018 IPR000644 CBS domain SMALA_RS34695 357193bc64f1dc331842ca29b4d68c5c 334 Gene3D G3DSA:3.20.20.70 164 334 5.4E-30 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS02900 8c2731810d05f233ec228f1f42971b9b 538 Gene3D G3DSA:1.20.1250.20 3 218 3.3E-37 T 29-03-2018 SMALA_RS02900 8c2731810d05f233ec228f1f42971b9b 538 PRINTS PR01036 Tetracycline resistance protein TetB signature 120 140 5.3E-7 T 29-03-2018 SMALA_RS02900 8c2731810d05f233ec228f1f42971b9b 538 PRINTS PR01036 Tetracycline resistance protein TetB signature 30 54 5.3E-7 T 29-03-2018 SMALA_RS02900 8c2731810d05f233ec228f1f42971b9b 538 PRINTS PR01036 Tetracycline resistance protein TetB signature 150 174 5.3E-7 T 29-03-2018 SMALA_RS02900 8c2731810d05f233ec228f1f42971b9b 538 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 27 437 5.8E-76 T 29-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 SMALA_RS02900 8c2731810d05f233ec228f1f42971b9b 538 Gene3D G3DSA:1.20.1250.20 271 536 1.9E-31 T 29-03-2018 SMALA_RS02900 8c2731810d05f233ec228f1f42971b9b 538 SUPERFAMILY SSF103473 267 439 9.29E-73 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS02900 8c2731810d05f233ec228f1f42971b9b 538 SUPERFAMILY SSF103473 4 218 9.29E-73 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS02900 8c2731810d05f233ec228f1f42971b9b 538 SUPERFAMILY SSF103473 506 533 9.29E-73 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS02900 8c2731810d05f233ec228f1f42971b9b 538 Pfam PF07690 Major Facilitator Superfamily 31 430 4.1E-55 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS13745 cb9d9758321a2dc2a57c5e15ee84eed7 284 Pfam PF13560 Helix-turn-helix domain 21 77 1.6E-15 T 29-03-2018 SMALA_RS13745 cb9d9758321a2dc2a57c5e15ee84eed7 284 SMART SM00530 25 80 2.4E-12 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS13745 cb9d9758321a2dc2a57c5e15ee84eed7 284 SUPERFAMILY SSF47413 20 76 9.85E-13 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS13745 cb9d9758321a2dc2a57c5e15ee84eed7 284 Gene3D G3DSA:1.10.260.40 10 92 1.9E-16 T 29-03-2018 SMALA_RS34815 e24a34d803b49edfc2ac0728d8bfeddc 231 SUPERFAMILY SSF52540 25 228 1.08E-37 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS34815 e24a34d803b49edfc2ac0728d8bfeddc 231 PIRSF PIRSF005624 20 231 1.2E-46 T 29-03-2018 IPR012202 [NiFe]-hydrogenase/urease maturation factor, Ni2-binding GTPase GO:0003924|GO:0016151 SMALA_RS34815 e24a34d803b49edfc2ac0728d8bfeddc 231 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 32 201 6.0E-35 T 29-03-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain SMALA_RS34815 e24a34d803b49edfc2ac0728d8bfeddc 231 TIGRFAM TIGR00101 ureG: urease accessory protein UreG 30 223 1.3E-84 T 29-03-2018 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 SMALA_RS34815 e24a34d803b49edfc2ac0728d8bfeddc 231 Hamap MF_01389 Urease accessory protein UreG [ureG]. 28 226 44.088 T 29-03-2018 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 SMALA_RS34815 e24a34d803b49edfc2ac0728d8bfeddc 231 Gene3D G3DSA:3.40.50.300 31 229 3.0E-18 T 29-03-2018 SMALA_RS29085 23d85ca042f79031c6815ab215cde8da 324 Gene3D G3DSA:3.40.30.10 136 230 3.0E-15 T 29-03-2018 SMALA_RS29085 23d85ca042f79031c6815ab215cde8da 324 PIRSF PIRSF035042 1 307 1.2E-69 T 29-03-2018 IPR010350 Thioredoxin-like ferredoxin, bacteria SMALA_RS29085 23d85ca042f79031c6815ab215cde8da 324 Pfam PF06999 Sucrase/ferredoxin-like 15 223 2.3E-21 T 29-03-2018 IPR009737 Thioredoxin-like ferredoxin SMALA_RS29085 23d85ca042f79031c6815ab215cde8da 324 SUPERFAMILY SSF52833 137 228 1.12E-13 T 29-03-2018 IPR012336 Thioredoxin-like fold SMALA_RS26910 4c07bcb7f1a45a1db765954962117021 523 SUPERFAMILY SSF50615 27 98 2.12E-22 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SMALA_RS26910 4c07bcb7f1a45a1db765954962117021 523 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 383 508 6.8E-45 T 29-03-2018 IPR000793 ATP synthase, alpha subunit, C-terminal GO:0015986 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMALA_RS26910 4c07bcb7f1a45a1db765954962117021 523 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 4 513 48.103 T 29-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMALA_RS26910 4c07bcb7f1a45a1db765954962117021 523 Gene3D G3DSA:3.40.50.300 87 376 1.5E-104 T 29-03-2018 SMALA_RS26910 4c07bcb7f1a45a1db765954962117021 523 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 6 512 1.6E-237 T 29-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMALA_RS26910 4c07bcb7f1a45a1db765954962117021 523 Gene3D G3DSA:2.40.30.20 6 86 1.3E-29 T 29-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMALA_RS26910 4c07bcb7f1a45a1db765954962117021 523 SUPERFAMILY SSF47917 385 512 9.68E-44 T 29-03-2018 SMALA_RS26910 4c07bcb7f1a45a1db765954962117021 523 Gene3D G3DSA:1.20.150.20 385 512 8.5E-48 T 29-03-2018 SMALA_RS26910 4c07bcb7f1a45a1db765954962117021 523 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 367 376 - T 29-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SMALA_RS26910 4c07bcb7f1a45a1db765954962117021 523 SUPERFAMILY SSF52540 100 382 1.81E-92 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS26910 4c07bcb7f1a45a1db765954962117021 523 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 153 376 2.1E-66 T 29-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SMALA_RS26910 4c07bcb7f1a45a1db765954962117021 523 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 30 96 3.8E-14 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SMALA_RS36085 60dd27ce401015ed503576ae14ae4165 283 Gene3D G3DSA:3.60.21.10 8 263 3.9E-19 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SMALA_RS36085 60dd27ce401015ed503576ae14ae4165 283 Pfam PF00149 Calcineurin-like phosphoesterase 9 242 9.5E-15 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 SMALA_RS36085 60dd27ce401015ed503576ae14ae4165 283 SUPERFAMILY SSF56300 217 260 6.08E-23 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SMALA_RS36085 60dd27ce401015ed503576ae14ae4165 283 SUPERFAMILY SSF56300 7 169 6.08E-23 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SMALA_RS36885 3c2c9e25f72d4738e25d0846e3dd93ff 215 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 66 1.5E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS36885 3c2c9e25f72d4738e25d0846e3dd93ff 215 SUPERFAMILY SSF46689 10 81 7.98E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS36885 3c2c9e25f72d4738e25d0846e3dd93ff 215 Gene3D G3DSA:1.10.357.10 1 204 8.5E-26 T 29-03-2018 SMALA_RS32300 0d224ec18e5538ae322cc9cc72664417 213 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 1 170 29.607 T 29-03-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 SMALA_RS32300 0d224ec18e5538ae322cc9cc72664417 213 Gene3D G3DSA:3.10.20.80 2 78 7.5E-31 T 29-03-2018 SMALA_RS32300 0d224ec18e5538ae322cc9cc72664417 213 SUPERFAMILY SSF55200 85 169 7.46E-32 T 29-03-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 SMALA_RS32300 0d224ec18e5538ae322cc9cc72664417 213 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 7 170 3.3E-61 T 29-03-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 SMALA_RS32300 0d224ec18e5538ae322cc9cc72664417 213 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 84 167 6.7E-34 T 29-03-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 SMALA_RS32300 0d224ec18e5538ae322cc9cc72664417 213 Gene3D G3DSA:3.30.110.10 79 178 4.0E-34 T 29-03-2018 SMALA_RS32300 0d224ec18e5538ae322cc9cc72664417 213 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 7 76 7.2E-29 T 29-03-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 SMALA_RS32300 0d224ec18e5538ae322cc9cc72664417 213 SUPERFAMILY SSF54364 5 78 3.01E-28 T 29-03-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 SMALA_RS12790 fb8ae5a22f299892f6084fdac37e038b 66 Pfam PF04149 Domain of unknown function (DUF397) 7 57 1.6E-16 T 29-03-2018 IPR007278 Domain of unknown function DUF397 SMALA_RS38590 65bfc9460fb32d587bde372d9f1dafbd 487 SUPERFAMILY SSF48208 267 454 4.19E-16 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 SMALA_RS38590 65bfc9460fb32d587bde372d9f1dafbd 487 Gene3D G3DSA:1.50.10.10 176 481 2.4E-23 T 29-03-2018 SMALA_RS38590 65bfc9460fb32d587bde372d9f1dafbd 487 Pfam PF07470 Glycosyl Hydrolase Family 88 283 440 3.1E-16 T 29-03-2018 IPR010905 Glycosyl hydrolase, family 88 SMALA_RS24280 e8a8fd8e045a68c391824ded1b410110 403 PRINTS PR00359 B-class P450 signature 139 155 2.3E-47 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS24280 e8a8fd8e045a68c391824ded1b410110 403 PRINTS PR00359 B-class P450 signature 194 216 2.3E-47 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS24280 e8a8fd8e045a68c391824ded1b410110 403 PRINTS PR00359 B-class P450 signature 343 352 2.3E-47 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS24280 e8a8fd8e045a68c391824ded1b410110 403 PRINTS PR00359 B-class P450 signature 322 337 2.3E-47 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS24280 e8a8fd8e045a68c391824ded1b410110 403 PRINTS PR00359 B-class P450 signature 156 171 2.3E-47 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS24280 e8a8fd8e045a68c391824ded1b410110 403 PRINTS PR00359 B-class P450 signature 352 363 2.3E-47 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS24280 e8a8fd8e045a68c391824ded1b410110 403 PRINTS PR00359 B-class P450 signature 294 321 2.3E-47 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS24280 e8a8fd8e045a68c391824ded1b410110 403 PRINTS PR00359 B-class P450 signature 276 287 2.3E-47 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS24280 e8a8fd8e045a68c391824ded1b410110 403 Pfam PF00067 Cytochrome P450 207 372 3.9E-17 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS24280 e8a8fd8e045a68c391824ded1b410110 403 PRINTS PR00385 P450 superfamily signature 352 363 9.0E-6 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS24280 e8a8fd8e045a68c391824ded1b410110 403 PRINTS PR00385 P450 superfamily signature 241 258 9.0E-6 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS24280 e8a8fd8e045a68c391824ded1b410110 403 PRINTS PR00385 P450 superfamily signature 343 352 9.0E-6 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS24280 e8a8fd8e045a68c391824ded1b410110 403 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 345 354 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMALA_RS24280 e8a8fd8e045a68c391824ded1b410110 403 SUPERFAMILY SSF48264 26 403 6.68E-80 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS24280 e8a8fd8e045a68c391824ded1b410110 403 Gene3D G3DSA:1.10.630.10 26 403 6.5E-59 T 29-03-2018 SMALA_RS14695 9b3813d67a88e37dc410c2db7eb91f57 375 Gene3D G3DSA:3.40.47.10 253 371 0.16 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS14695 9b3813d67a88e37dc410c2db7eb91f57 375 SUPERFAMILY SSF53901 11 245 1.58E-30 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS14695 9b3813d67a88e37dc410c2db7eb91f57 375 Gene3D G3DSA:3.40.47.10 11 252 1.7E-35 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS14695 9b3813d67a88e37dc410c2db7eb91f57 375 SUPERFAMILY SSF53901 211 365 3.34E-9 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS14695 9b3813d67a88e37dc410c2db7eb91f57 375 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 11 239 5.8E-15 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS01305 6b85abc71e48ef9a2341663f4c73ada6 313 SUPERFAMILY SSF88946 14 99 9.02E-17 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS01305 6b85abc71e48ef9a2341663f4c73ada6 313 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 16 172 7.9E-16 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS01305 6b85abc71e48ef9a2341663f4c73ada6 313 Gene3D G3DSA:3.10.450.50 164 304 2.3E-17 T 29-03-2018 SMALA_RS01305 6b85abc71e48ef9a2341663f4c73ada6 313 SUPERFAMILY SSF88659 112 172 1.5E-6 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS01305 6b85abc71e48ef9a2341663f4c73ada6 313 Pfam PF04542 Sigma-70 region 2 20 83 3.2E-14 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS01305 6b85abc71e48ef9a2341663f4c73ada6 313 Gene3D G3DSA:1.10.10.10 87 163 4.8E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS01305 6b85abc71e48ef9a2341663f4c73ada6 313 SUPERFAMILY SSF54427 185 299 1.45E-12 T 29-03-2018 IPR032710 NTF2-like domain SMALA_RS01305 6b85abc71e48ef9a2341663f4c73ada6 313 Gene3D G3DSA:1.10.1740.10 7 86 1.3E-18 T 29-03-2018 SMALA_RS07325 7778c8d64fe85477df9e5b31afaa1c61 515 Gene3D G3DSA:3.30.420.40 262 515 1.2E-79 T 29-03-2018 SMALA_RS07325 7778c8d64fe85477df9e5b31afaa1c61 515 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 274 464 9.4E-66 T 29-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 SMALA_RS07325 7778c8d64fe85477df9e5b31afaa1c61 515 SUPERFAMILY SSF53067 17 268 1.46E-93 T 29-03-2018 SMALA_RS07325 7778c8d64fe85477df9e5b31afaa1c61 515 Hamap MF_00186 Glycerol kinase [glpK]. 15 511 56.215 T 29-03-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 SMALA_RS07325 7778c8d64fe85477df9e5b31afaa1c61 515 PIRSF PIRSF000538 15 515 2.9E-169 T 29-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 SMALA_RS07325 7778c8d64fe85477df9e5b31afaa1c61 515 Gene3D G3DSA:3.30.420.40 13 261 2.5E-95 T 29-03-2018 SMALA_RS07325 7778c8d64fe85477df9e5b31afaa1c61 515 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 376 396 - T 29-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 SMALA_RS07325 7778c8d64fe85477df9e5b31afaa1c61 515 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 18 265 3.2E-81 T 29-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 SMALA_RS07325 7778c8d64fe85477df9e5b31afaa1c61 515 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 16 510 3.9E-228 T 29-03-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 SMALA_RS07325 7778c8d64fe85477df9e5b31afaa1c61 515 SUPERFAMILY SSF53067 268 511 3.37E-82 T 29-03-2018 SMALA_RS26810 3577201f79f5504304040c0508c15425 140 SUPERFAMILY SSF52172 4 120 5.41E-35 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS26810 3577201f79f5504304040c0508c15425 140 SMART SM00448 3 115 4.8E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS26810 3577201f79f5504304040c0508c15425 140 Gene3D G3DSA:3.40.50.2300 2 132 2.0E-34 T 29-03-2018 SMALA_RS26810 3577201f79f5504304040c0508c15425 140 Pfam PF00072 Response regulator receiver domain 5 115 3.3E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS26265 c24f7acab32a922128a73237dbf4499f 286 SMART SM00530 17 72 2.3E-7 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS26265 c24f7acab32a922128a73237dbf4499f 286 SUPERFAMILY SSF47413 10 73 5.09E-11 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS26265 c24f7acab32a922128a73237dbf4499f 286 Pfam PF13560 Helix-turn-helix domain 13 70 1.5E-10 T 29-03-2018 SMALA_RS26265 c24f7acab32a922128a73237dbf4499f 286 Gene3D G3DSA:1.10.260.40 4 86 8.7E-13 T 29-03-2018 SMALA_RS41930 2750bf9c82429f97ae9a7aa920de59e0 295 Gene3D G3DSA:3.40.50.1820 5 292 2.4E-44 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS41930 2750bf9c82429f97ae9a7aa920de59e0 295 PRINTS PR00111 Alpha/beta hydrolase fold signature 102 115 3.7E-10 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS41930 2750bf9c82429f97ae9a7aa920de59e0 295 PRINTS PR00111 Alpha/beta hydrolase fold signature 116 129 3.7E-10 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS41930 2750bf9c82429f97ae9a7aa920de59e0 295 PRINTS PR00111 Alpha/beta hydrolase fold signature 56 71 3.7E-10 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS41930 2750bf9c82429f97ae9a7aa920de59e0 295 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 102 116 2.6E-11 T 29-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 SMALA_RS41930 2750bf9c82429f97ae9a7aa920de59e0 295 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 59 70 2.6E-11 T 29-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 SMALA_RS41930 2750bf9c82429f97ae9a7aa920de59e0 295 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 31 39 2.6E-11 T 29-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 SMALA_RS41930 2750bf9c82429f97ae9a7aa920de59e0 295 Pfam PF00561 alpha/beta hydrolase fold 30 139 3.6E-21 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS41930 2750bf9c82429f97ae9a7aa920de59e0 295 SUPERFAMILY SSF53474 11 291 5.32E-49 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS23345 fe4e5689b4ece3c9f7fd88d36a9cc756 331 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 25 304 4.6E-19 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMALA_RS23345 fe4e5689b4ece3c9f7fd88d36a9cc756 331 PIRSF PIRSF006278 3 307 3.2E-65 T 29-03-2018 IPR027278 1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase SMALA_RS23345 fe4e5689b4ece3c9f7fd88d36a9cc756 331 Gene3D G3DSA:3.40.50.1100 144 312 2.3E-15 T 29-03-2018 SMALA_RS23345 fe4e5689b4ece3c9f7fd88d36a9cc756 331 SUPERFAMILY SSF53686 22 304 3.17E-46 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMALA_RS23345 fe4e5689b4ece3c9f7fd88d36a9cc756 331 Gene3D G3DSA:3.40.50.1100 45 143 1.9E-26 T 29-03-2018 SMALA_RS15670 33842f2db351e2aeadd9b6038eefc931 254 Pfam PF00156 Phosphoribosyl transferase domain 206 251 3.2E-6 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 SMALA_RS15670 33842f2db351e2aeadd9b6038eefc931 254 Gene3D G3DSA:3.40.50.2020 59 253 1.1E-24 T 29-03-2018 SMALA_RS15670 33842f2db351e2aeadd9b6038eefc931 254 SUPERFAMILY SSF53271 131 251 3.59E-14 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like SMALA_RS27120 f13e130bcec68d7052f84252e45dddcb 110 TIGRFAM TIGR03954 integ_memb_HG: integral membrane protein 9 92 3.9E-28 T 29-03-2018 IPR023845 Domain of unknown function DUF3817, transmembrane SMALA_RS27120 f13e130bcec68d7052f84252e45dddcb 110 Pfam PF12823 Domain of unknown function (DUF3817) 6 93 1.1E-27 T 29-03-2018 IPR023845 Domain of unknown function DUF3817, transmembrane SMALA_RS39590 e1a9fed411987bc1236839315e055ca4 518 Gene3D G3DSA:3.30.70.20 244 381 1.6E-29 T 29-03-2018 SMALA_RS39590 e1a9fed411987bc1236839315e055ca4 518 Gene3D G3DSA:3.30.70.20 382 477 8.3E-26 T 29-03-2018 SMALA_RS39590 e1a9fed411987bc1236839315e055ca4 518 Gene3D G3DSA:3.30.70.20 6 28 0.04 T 29-03-2018 SMALA_RS39590 e1a9fed411987bc1236839315e055ca4 518 TIGRFAM TIGR01660 narH: nitrate reductase, beta subunit 9 493 7.1E-221 T 29-03-2018 IPR006547 Nitrate reductase, beta subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.99.4 SMALA_RS39590 e1a9fed411987bc1236839315e055ca4 518 SUPERFAMILY SSF54862 9 502 5.86E-154 T 29-03-2018 SMALA_RS39590 e1a9fed411987bc1236839315e055ca4 518 Gene3D G3DSA:3.30.70.20 206 243 8.1E-18 T 29-03-2018 SMALA_RS39590 e1a9fed411987bc1236839315e055ca4 518 Gene3D G3DSA:3.30.70.20 29 205 1.3E-23 T 29-03-2018 SMALA_RS39590 e1a9fed411987bc1236839315e055ca4 518 Pfam PF14711 Respiratory nitrate reductase beta C-terminal 366 446 1.5E-25 T 29-03-2018 IPR029263 Respiratory nitrate reductase beta, C-terminal KEGG: 00910+1.7.99.4 SMALA_RS39590 e1a9fed411987bc1236839315e055ca4 518 Pfam PF13247 4Fe-4S dicluster domain 184 278 1.4E-34 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain SMALA_RS16270 f27d509d94cc3d75ce2720592ecefd94 330 SUPERFAMILY SSF101386 135 233 7.52E-22 T 29-03-2018 SMALA_RS16270 f27d509d94cc3d75ce2720592ecefd94 330 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 154 228 4.4E-25 T 29-03-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core SMALA_RS16270 f27d509d94cc3d75ce2720592ecefd94 330 Gene3D G3DSA:1.10.287.1080 132 250 5.5E-41 T 29-03-2018 SMALA_RS14385 4501daac5a9d9dfadd9ea357857648ae 963 Gene3D G3DSA:4.10.870.10 887 927 1.0E-30 T 29-03-2018 IPR027390 Endoglucanase F, domain 3 SMALA_RS14385 4501daac5a9d9dfadd9ea357857648ae 963 SMART SM00637 34 133 4.7E-44 T 29-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 SMALA_RS14385 4501daac5a9d9dfadd9ea357857648ae 963 Gene3D G3DSA:2.40.50.70 124 174 1.7E-8 T 29-03-2018 SMALA_RS14385 4501daac5a9d9dfadd9ea357857648ae 963 SUPERFAMILY SSF48208 328 963 2.58E-297 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 SMALA_RS14385 4501daac5a9d9dfadd9ea357857648ae 963 Pfam PF02011 Glycosyl hydrolase family 48 334 962 0.0 T 29-03-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 SMALA_RS14385 4501daac5a9d9dfadd9ea357857648ae 963 Gene3D G3DSA:2.60.40.10 175 225 0.0038 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS14385 4501daac5a9d9dfadd9ea357857648ae 963 PRINTS PR00844 Glycosyl hydrolase family 48 signature 692 715 9.7E-110 T 29-03-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 SMALA_RS14385 4501daac5a9d9dfadd9ea357857648ae 963 PRINTS PR00844 Glycosyl hydrolase family 48 signature 793 813 9.7E-110 T 29-03-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 SMALA_RS14385 4501daac5a9d9dfadd9ea357857648ae 963 PRINTS PR00844 Glycosyl hydrolase family 48 signature 504 528 9.7E-110 T 29-03-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 SMALA_RS14385 4501daac5a9d9dfadd9ea357857648ae 963 PRINTS PR00844 Glycosyl hydrolase family 48 signature 549 576 9.7E-110 T 29-03-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 SMALA_RS14385 4501daac5a9d9dfadd9ea357857648ae 963 PRINTS PR00844 Glycosyl hydrolase family 48 signature 383 400 9.7E-110 T 29-03-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 SMALA_RS14385 4501daac5a9d9dfadd9ea357857648ae 963 PRINTS PR00844 Glycosyl hydrolase family 48 signature 895 923 9.7E-110 T 29-03-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 SMALA_RS14385 4501daac5a9d9dfadd9ea357857648ae 963 PRINTS PR00844 Glycosyl hydrolase family 48 signature 622 641 9.7E-110 T 29-03-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 SMALA_RS14385 4501daac5a9d9dfadd9ea357857648ae 963 PRINTS PR00844 Glycosyl hydrolase family 48 signature 738 764 9.7E-110 T 29-03-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 SMALA_RS14385 4501daac5a9d9dfadd9ea357857648ae 963 PRINTS PR00844 Glycosyl hydrolase family 48 signature 357 382 9.7E-110 T 29-03-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 SMALA_RS14385 4501daac5a9d9dfadd9ea357857648ae 963 SUPERFAMILY SSF49384 33 134 5.23E-30 T 29-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 SMALA_RS14385 4501daac5a9d9dfadd9ea357857648ae 963 Pfam PF00553 Cellulose binding domain 36 133 5.2E-26 T 29-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 SMALA_RS14385 4501daac5a9d9dfadd9ea357857648ae 963 Gene3D G3DSA:2.60.40.10 228 327 1.7E-8 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS14385 4501daac5a9d9dfadd9ea357857648ae 963 Gene3D G3DSA:2.60.40.290 25 123 1.2E-31 T 29-03-2018 SMALA_RS14385 4501daac5a9d9dfadd9ea357857648ae 963 Gene3D G3DSA:1.50.10.10 333 508 1.1E-56 T 29-03-2018 SMALA_RS14385 4501daac5a9d9dfadd9ea357857648ae 963 Gene3D G3DSA:1.50.10.10 526 886 7.8E-160 T 29-03-2018 SMALA_RS14385 4501daac5a9d9dfadd9ea357857648ae 963 Gene3D G3DSA:1.50.10.10 928 963 0.053 T 29-03-2018 SMALA_RS31120 aee852b2ee9d3c8d5f5616dc535e3bc9 260 Gene3D G3DSA:3.60.15.10 1 260 5.3E-30 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS31120 aee852b2ee9d3c8d5f5616dc535e3bc9 260 SUPERFAMILY SSF56281 4 213 3.5E-24 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS31120 aee852b2ee9d3c8d5f5616dc535e3bc9 260 Pfam PF12706 Beta-lactamase superfamily domain 21 209 3.1E-29 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS08135 9ff7bd771b4d64917009da2bd4dd6e14 547 Pfam PF00501 AMP-binding enzyme 31 454 1.3E-100 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS08135 9ff7bd771b4d64917009da2bd4dd6e14 547 ProSitePatterns PS00455 Putative AMP-binding domain signature. 204 215 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS08135 9ff7bd771b4d64917009da2bd4dd6e14 547 SUPERFAMILY SSF56801 26 546 4.84E-153 T 29-03-2018 SMALA_RS08135 9ff7bd771b4d64917009da2bd4dd6e14 547 Gene3D G3DSA:2.30.38.10 366 448 2.1E-23 T 29-03-2018 SMALA_RS08135 9ff7bd771b4d64917009da2bd4dd6e14 547 Gene3D G3DSA:3.40.50.980 210 365 3.0E-41 T 29-03-2018 SMALA_RS08135 9ff7bd771b4d64917009da2bd4dd6e14 547 Pfam PF13193 AMP-binding enzyme C-terminal domain 464 539 1.9E-24 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS08135 9ff7bd771b4d64917009da2bd4dd6e14 547 Gene3D G3DSA:3.40.50.980 24 209 9.1E-44 T 29-03-2018 SMALA_RS08135 9ff7bd771b4d64917009da2bd4dd6e14 547 Gene3D G3DSA:3.30.300.30 449 547 1.0E-29 T 29-03-2018 SMALA_RS37355 e0335fedd6b4f72d90099d84ff4b7e58 500 Gene3D G3DSA:3.20.20.140 54 346 2.0E-8 T 29-03-2018 SMALA_RS37355 e0335fedd6b4f72d90099d84ff4b7e58 500 SUPERFAMILY SSF89550 289 352 4.51E-10 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 SMALA_RS37355 e0335fedd6b4f72d90099d84ff4b7e58 500 SUPERFAMILY SSF89550 62 166 4.51E-10 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 SMALA_RS37355 e0335fedd6b4f72d90099d84ff4b7e58 500 SUPERFAMILY SSF89550 209 258 4.51E-10 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 SMALA_RS15070 c4c56482a08b0c4c0f330d83baa49c7f 448 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 163 330 2.0E-4 T 29-03-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 SMALA_RS15070 c4c56482a08b0c4c0f330d83baa49c7f 448 Gene3D G3DSA:3.20.140.10 9 385 1.9E-101 T 29-03-2018 SMALA_RS15070 c4c56482a08b0c4c0f330d83baa49c7f 448 TIGRFAM TIGR01513 NAPRTase_put: nicotinate phosphoribosyltransferase 16 385 1.0E-129 T 29-03-2018 IPR006405 Nicotinate phosphoribosyltransferase pncB-type GO:0004516|GO:0019358 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264|Reactome: R-HSA-6798695 SMALA_RS15070 c4c56482a08b0c4c0f330d83baa49c7f 448 SUPERFAMILY SSF51690 146 438 2.06E-79 T 29-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 SMALA_RS15070 c4c56482a08b0c4c0f330d83baa49c7f 448 PIRSF PIRSF000484 8 441 3.0E-106 T 29-03-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 SMALA_RS15070 c4c56482a08b0c4c0f330d83baa49c7f 448 SUPERFAMILY SSF54675 11 144 8.03E-45 T 29-03-2018 SMALA_RS24045 b86687336688485105c04e67d85eb6aa 196 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 7 188 32.728 T 29-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 SMALA_RS24045 b86687336688485105c04e67d85eb6aa 196 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 9 195 1.1E-50 T 29-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 SMALA_RS24045 b86687336688485105c04e67d85eb6aa 196 SUPERFAMILY SSF53178 7 195 1.96E-62 T 29-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 SMALA_RS24045 b86687336688485105c04e67d85eb6aa 196 Pfam PF01195 Peptidyl-tRNA hydrolase 9 195 5.0E-51 T 29-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 SMALA_RS24045 b86687336688485105c04e67d85eb6aa 196 Gene3D G3DSA:3.40.50.1470 1 196 1.2E-67 T 29-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 SMALA_RS24045 b86687336688485105c04e67d85eb6aa 196 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 20 33 - T 29-03-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 SMALA_RS24045 b86687336688485105c04e67d85eb6aa 196 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 118 128 - T 29-03-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 SMALA_RS12010 1082b74fd15ae53cd618c71f1b8b8e6c 282 SUPERFAMILY SSF56601 6 265 6.3E-56 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMALA_RS12010 1082b74fd15ae53cd618c71f1b8b8e6c 282 Gene3D G3DSA:3.40.710.10 2 277 1.3E-56 T 29-03-2018 SMALA_RS12010 1082b74fd15ae53cd618c71f1b8b8e6c 282 Pfam PF00144 Beta-lactamase 12 251 5.8E-40 T 29-03-2018 IPR001466 Beta-lactamase-related SMALA_RS18265 d8d1ba4ac978379447351ea89b91c758 356 Pfam PF01341 Glycosyl hydrolases family 6 85 340 6.2E-66 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMALA_RS18265 d8d1ba4ac978379447351ea89b91c758 356 SUPERFAMILY SSF51989 74 355 2.88E-83 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMALA_RS18265 d8d1ba4ac978379447351ea89b91c758 356 PIRSF PIRSF001100 33 356 8.8E-84 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMALA_RS18265 d8d1ba4ac978379447351ea89b91c758 356 PRINTS PR00733 Glycosyl hydrolase family 6 signature 221 234 9.2E-35 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMALA_RS18265 d8d1ba4ac978379447351ea89b91c758 356 PRINTS PR00733 Glycosyl hydrolase family 6 signature 300 320 9.2E-35 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMALA_RS18265 d8d1ba4ac978379447351ea89b91c758 356 PRINTS PR00733 Glycosyl hydrolase family 6 signature 137 150 9.2E-35 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMALA_RS18265 d8d1ba4ac978379447351ea89b91c758 356 PRINTS PR00733 Glycosyl hydrolase family 6 signature 165 180 9.2E-35 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMALA_RS18265 d8d1ba4ac978379447351ea89b91c758 356 PRINTS PR00733 Glycosyl hydrolase family 6 signature 252 262 9.2E-35 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMALA_RS18265 d8d1ba4ac978379447351ea89b91c758 356 PRINTS PR00733 Glycosyl hydrolase family 6 signature 324 338 9.2E-35 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMALA_RS18265 d8d1ba4ac978379447351ea89b91c758 356 PRINTS PR00733 Glycosyl hydrolase family 6 signature 94 113 9.2E-35 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMALA_RS18265 d8d1ba4ac978379447351ea89b91c758 356 PRINTS PR00733 Glycosyl hydrolase family 6 signature 284 297 9.2E-35 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMALA_RS18265 d8d1ba4ac978379447351ea89b91c758 356 ProSitePatterns PS00656 Glycosyl hydrolases family 6 signature 2. 182 191 - T 29-03-2018 IPR001524 Glycoside hydrolase, family 6, conserved site GO:0004553|GO:0005975 SMALA_RS18265 d8d1ba4ac978379447351ea89b91c758 356 Gene3D G3DSA:3.20.20.40 72 356 4.2E-86 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMALA_RS19210 643c03338ef021f5a211354ba2da99e4 378 SMART SM00943 13 274 6.4E-33 T 29-03-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal SMALA_RS19210 643c03338ef021f5a211354ba2da99e4 378 SUPERFAMILY SSF56747 194 283 1.05E-16 T 29-03-2018 SMALA_RS19210 643c03338ef021f5a211354ba2da99e4 378 SMART SM00942 307 369 5.3E-10 T 29-03-2018 IPR014820 Primase, C-terminal 1 SMALA_RS19210 643c03338ef021f5a211354ba2da99e4 378 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 13 271 4.0E-37 T 29-03-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal SMALA_RS19210 643c03338ef021f5a211354ba2da99e4 378 SUPERFAMILY SSF56747 8 109 2.42E-8 T 29-03-2018 SMALA_RS30695 1c895e61afe7a62b6faf02d64bf7ce22 289 Gene3D G3DSA:1.10.3720.10 59 265 1.1E-37 T 29-03-2018 SMALA_RS30695 1c895e61afe7a62b6faf02d64bf7ce22 289 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 264 3.1E-19 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS30695 1c895e61afe7a62b6faf02d64bf7ce22 289 SUPERFAMILY SSF161098 64 252 7.46E-36 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS30695 1c895e61afe7a62b6faf02d64bf7ce22 289 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 65 155 1.3E-17 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 SMALA_RS08415 20b41f73c9f42a30639d63d466af7560 282 SMART SM00530 21 76 0.0057 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS08415 20b41f73c9f42a30639d63d466af7560 282 Gene3D G3DSA:1.10.3100.10 12 151 2.0E-9 T 29-03-2018 IPR027910 YdiL-like domain SMALA_RS08415 20b41f73c9f42a30639d63d466af7560 282 Pfam PF13560 Helix-turn-helix domain 18 68 1.7E-6 T 29-03-2018 SMALA_RS08415 20b41f73c9f42a30639d63d466af7560 282 SUPERFAMILY SSF47413 16 72 2.08E-7 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS20435 6ee8b18209eff0979a82b6fd63c9c873 241 Gene3D G3DSA:3.40.190.10 6 234 9.8E-4 T 29-03-2018 SMALA_RS20435 6ee8b18209eff0979a82b6fd63c9c873 241 Pfam PF14016 Protein of unknown function (DUF4232) 109 232 4.6E-23 T 29-03-2018 IPR025326 Protein of unknown function DUF4232 SMALA_RS03785 3b596b639f7347142ad678a6a02fa973 453 PRINTS PR00463 E-class P450 group I signature 43 62 3.5E-25 T 29-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS03785 3b596b639f7347142ad678a6a02fa973 453 PRINTS PR00463 E-class P450 group I signature 392 402 3.5E-25 T 29-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS03785 3b596b639f7347142ad678a6a02fa973 453 PRINTS PR00463 E-class P450 group I signature 255 272 3.5E-25 T 29-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS03785 3b596b639f7347142ad678a6a02fa973 453 PRINTS PR00463 E-class P450 group I signature 275 301 3.5E-25 T 29-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS03785 3b596b639f7347142ad678a6a02fa973 453 PRINTS PR00463 E-class P450 group I signature 402 425 3.5E-25 T 29-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS03785 3b596b639f7347142ad678a6a02fa973 453 PRINTS PR00463 E-class P450 group I signature 357 381 3.5E-25 T 29-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS03785 3b596b639f7347142ad678a6a02fa973 453 Gene3D G3DSA:1.10.630.10 16 453 7.2E-123 T 29-03-2018 SMALA_RS03785 3b596b639f7347142ad678a6a02fa973 453 PRINTS PR00385 P450 superfamily signature 318 329 1.9E-11 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS03785 3b596b639f7347142ad678a6a02fa973 453 PRINTS PR00385 P450 superfamily signature 393 402 1.9E-11 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS03785 3b596b639f7347142ad678a6a02fa973 453 PRINTS PR00385 P450 superfamily signature 266 283 1.9E-11 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS03785 3b596b639f7347142ad678a6a02fa973 453 PRINTS PR00385 P450 superfamily signature 402 413 1.9E-11 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS03785 3b596b639f7347142ad678a6a02fa973 453 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 395 404 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMALA_RS03785 3b596b639f7347142ad678a6a02fa973 453 Pfam PF00067 Cytochrome P450 22 438 4.1E-83 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS03785 3b596b639f7347142ad678a6a02fa973 453 SUPERFAMILY SSF48264 20 453 2.62E-111 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS37415 a92d3aa81933d9d3d7737f428bb8572a 855 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 615 627 2.6E-37 T 29-03-2018 SMALA_RS37415 a92d3aa81933d9d3d7737f428bb8572a 855 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 493 504 2.6E-37 T 29-03-2018 SMALA_RS37415 a92d3aa81933d9d3d7737f428bb8572a 855 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 139 153 2.6E-37 T 29-03-2018 SMALA_RS37415 a92d3aa81933d9d3d7737f428bb8572a 855 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 515 525 2.6E-37 T 29-03-2018 SMALA_RS37415 a92d3aa81933d9d3d7737f428bb8572a 855 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 293 307 2.6E-37 T 29-03-2018 SMALA_RS37415 a92d3aa81933d9d3d7737f428bb8572a 855 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 591 610 2.6E-37 T 29-03-2018 SMALA_RS37415 a92d3aa81933d9d3d7737f428bb8572a 855 SMART SM00831 1 54 2.4E-11 T 29-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 SMALA_RS37415 a92d3aa81933d9d3d7737f428bb8572a 855 Pfam PF00122 E1-E2 ATPase 89 272 2.6E-52 T 29-03-2018 SMALA_RS37415 a92d3aa81933d9d3d7737f428bb8572a 855 SUPERFAMILY SSF56784 449 694 1.39E-52 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS37415 a92d3aa81933d9d3d7737f428bb8572a 855 SUPERFAMILY SSF56784 291 311 1.39E-52 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS37415 a92d3aa81933d9d3d7737f428bb8572a 855 SUPERFAMILY SSF81665 194 287 1.96E-104 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SMALA_RS37415 a92d3aa81933d9d3d7737f428bb8572a 855 SUPERFAMILY SSF81665 641 838 1.96E-104 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SMALA_RS37415 a92d3aa81933d9d3d7737f428bb8572a 855 SUPERFAMILY SSF81665 1 92 1.96E-104 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SMALA_RS37415 a92d3aa81933d9d3d7737f428bb8572a 855 Pfam PF00690 Cation transporter/ATPase, N-terminus 1 48 9.1E-14 T 29-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 SMALA_RS37415 a92d3aa81933d9d3d7737f428bb8572a 855 Pfam PF13246 Cation transport ATPase (P-type) 354 437 5.9E-21 T 29-03-2018 SMALA_RS37415 a92d3aa81933d9d3d7737f428bb8572a 855 SUPERFAMILY SSF81653 92 194 5.1E-26 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 SMALA_RS37415 a92d3aa81933d9d3d7737f428bb8572a 855 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 548 682 5.2E-31 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMALA_RS37415 a92d3aa81933d9d3d7737f428bb8572a 855 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 60 314 4.8E-45 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMALA_RS37415 a92d3aa81933d9d3d7737f428bb8572a 855 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 393 542 1.4E-18 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMALA_RS37415 a92d3aa81933d9d3d7737f428bb8572a 855 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 295 301 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 SMALA_RS37415 a92d3aa81933d9d3d7737f428bb8572a 855 Gene3D G3DSA:3.40.50.1000 495 611 9.9E-20 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS37415 a92d3aa81933d9d3d7737f428bb8572a 855 SUPERFAMILY SSF81660 300 497 2.94E-48 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 SMALA_RS37415 a92d3aa81933d9d3d7737f428bb8572a 855 Gene3D G3DSA:1.20.1110.10 612 845 8.7E-51 T 29-03-2018 SMALA_RS37415 a92d3aa81933d9d3d7737f428bb8572a 855 Gene3D G3DSA:3.40.1110.10 333 494 1.8E-36 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 SMALA_RS37415 a92d3aa81933d9d3d7737f428bb8572a 855 Pfam PF00689 Cation transporting ATPase, C-terminus 675 833 2.4E-32 T 29-03-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 SMALA_RS37415 a92d3aa81933d9d3d7737f428bb8572a 855 Gene3D G3DSA:2.70.150.10 1 195 7.1E-42 T 29-03-2018 SMALA_RS37415 a92d3aa81933d9d3d7737f428bb8572a 855 Gene3D G3DSA:3.40.1110.10 252 316 3.7E-12 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 SMALA_RS37415 a92d3aa81933d9d3d7737f428bb8572a 855 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 623 648 1.7E-16 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMALA_RS37415 a92d3aa81933d9d3d7737f428bb8572a 855 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 563 579 1.7E-16 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMALA_RS37415 a92d3aa81933d9d3d7737f428bb8572a 855 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 452 470 1.7E-16 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMALA_RS37415 a92d3aa81933d9d3d7737f428bb8572a 855 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 591 607 1.7E-16 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMALA_RS20255 627e9ecffdc3f6a290972db8987b8c48 225 Pfam PF00196 Bacterial regulatory proteins, luxR family 165 219 5.3E-17 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS20255 627e9ecffdc3f6a290972db8987b8c48 225 SMART SM00448 8 121 1.7E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS20255 627e9ecffdc3f6a290972db8987b8c48 225 Gene3D G3DSA:3.40.50.2300 7 132 1.1E-31 T 29-03-2018 SMALA_RS20255 627e9ecffdc3f6a290972db8987b8c48 225 Pfam PF00072 Response regulator receiver domain 10 121 2.0E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS20255 627e9ecffdc3f6a290972db8987b8c48 225 SUPERFAMILY SSF52172 7 134 1.85E-32 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS20255 627e9ecffdc3f6a290972db8987b8c48 225 Gene3D G3DSA:1.10.10.10 133 224 1.3E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS20255 627e9ecffdc3f6a290972db8987b8c48 225 SMART SM00421 163 220 2.7E-19 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS20255 627e9ecffdc3f6a290972db8987b8c48 225 SUPERFAMILY SSF46894 156 221 1.36E-17 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS20255 627e9ecffdc3f6a290972db8987b8c48 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 196 3.2E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS20255 627e9ecffdc3f6a290972db8987b8c48 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 196 208 3.2E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS20255 627e9ecffdc3f6a290972db8987b8c48 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 180 3.2E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS20255 627e9ecffdc3f6a290972db8987b8c48 225 ProSitePatterns PS00622 LuxR-type HTH domain signature. 180 207 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS24480 621415e4db04eb7a31c0ba5d9170b359 327 SMART SM00829 10 325 1.7E-9 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS24480 621415e4db04eb7a31c0ba5d9170b359 327 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 90 1.4E-7 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS24480 621415e4db04eb7a31c0ba5d9170b359 327 Pfam PF13602 Zinc-binding dehydrogenase 195 325 4.0E-12 T 29-03-2018 SMALA_RS24480 621415e4db04eb7a31c0ba5d9170b359 327 SUPERFAMILY SSF50129 1 151 5.17E-29 T 29-03-2018 IPR011032 GroES-like SMALA_RS24480 621415e4db04eb7a31c0ba5d9170b359 327 SUPERFAMILY SSF51735 128 278 1.67E-24 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS24480 621415e4db04eb7a31c0ba5d9170b359 327 Gene3D G3DSA:3.90.180.10 1 144 1.2E-30 T 29-03-2018 SMALA_RS24480 621415e4db04eb7a31c0ba5d9170b359 327 Gene3D G3DSA:3.40.50.720 145 301 1.6E-18 T 29-03-2018 SMALA_RS41760 e01b4a812763946ac00d7cef7222df5e 1364 Pfam PF12770 CHAT domain 1099 1363 1.1E-42 T 29-03-2018 IPR024983 CHAT domain SMALA_RS41760 e01b4a812763946ac00d7cef7222df5e 1364 Gene3D G3DSA:1.20.5.1140 750 790 3.8E-6 T 29-03-2018 SMALA_RS41760 e01b4a812763946ac00d7cef7222df5e 1364 Gene3D G3DSA:1.20.5.1140 661 701 0.0029 T 29-03-2018 SMALA_RS41760 e01b4a812763946ac00d7cef7222df5e 1364 Gene3D G3DSA:1.20.5.1140 616 656 7.1E-5 T 29-03-2018 SMALA_RS41760 e01b4a812763946ac00d7cef7222df5e 1364 Gene3D G3DSA:1.20.5.1140 267 300 0.047 T 29-03-2018 SMALA_RS41760 e01b4a812763946ac00d7cef7222df5e 1364 Gene3D G3DSA:1.20.5.1140 175 217 1.9E-4 T 29-03-2018 SMALA_RS41760 e01b4a812763946ac00d7cef7222df5e 1364 Gene3D G3DSA:1.20.5.1140 792 834 6.2E-8 T 29-03-2018 SMALA_RS41760 e01b4a812763946ac00d7cef7222df5e 1364 Gene3D G3DSA:1.20.5.1140 348 386 0.0035 T 29-03-2018 SMALA_RS41760 e01b4a812763946ac00d7cef7222df5e 1364 Gene3D G3DSA:1.20.5.1140 219 262 0.011 T 29-03-2018 SMALA_RS41760 e01b4a812763946ac00d7cef7222df5e 1364 Gene3D G3DSA:1.20.5.1140 490 515 5.9E-6 T 29-03-2018 SMALA_RS41760 e01b4a812763946ac00d7cef7222df5e 1364 Gene3D G3DSA:1.20.5.1140 574 610 6.0E-5 T 29-03-2018 SMALA_RS41760 e01b4a812763946ac00d7cef7222df5e 1364 Gene3D G3DSA:1.20.5.1140 128 174 0.02 T 29-03-2018 SMALA_RS41760 e01b4a812763946ac00d7cef7222df5e 1364 Gene3D G3DSA:1.20.5.1140 705 744 1.3E-4 T 29-03-2018 SMALA_RS41760 e01b4a812763946ac00d7cef7222df5e 1364 Gene3D G3DSA:1.20.5.1140 389 420 0.016 T 29-03-2018 SMALA_RS41760 e01b4a812763946ac00d7cef7222df5e 1364 Gene3D G3DSA:1.20.1250.10 421 489 0.14 T 29-03-2018 SMALA_RS41760 e01b4a812763946ac00d7cef7222df5e 1364 Gene3D G3DSA:3.40.50.1460 1147 1364 3.2E-17 T 29-03-2018 SMALA_RS41760 e01b4a812763946ac00d7cef7222df5e 1364 SUPERFAMILY SSF48452 536 781 4.83E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS41760 e01b4a812763946ac00d7cef7222df5e 1364 Gene3D G3DSA:1.25.40.10 516 573 0.0023 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS41760 e01b4a812763946ac00d7cef7222df5e 1364 SUPERFAMILY SSF48452 457 606 2.6E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS42270 f18c16488c1fbd0c49b6583a777f917c 281 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 11 191 0.0061 T 29-03-2018 SMALA_RS42270 f18c16488c1fbd0c49b6583a777f917c 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 148 1.8E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS42270 f18c16488c1fbd0c49b6583a777f917c 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 1.8E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS42270 f18c16488c1fbd0c49b6583a777f917c 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 86 97 1.8E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS42270 f18c16488c1fbd0c49b6583a777f917c 281 Gene3D G3DSA:3.40.50.720 2 253 9.2E-72 T 29-03-2018 SMALA_RS42270 f18c16488c1fbd0c49b6583a777f917c 281 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 253 5.4E-66 T 29-03-2018 SMALA_RS42270 f18c16488c1fbd0c49b6583a777f917c 281 SUPERFAMILY SSF51735 9 254 2.18E-79 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS42270 f18c16488c1fbd0c49b6583a777f917c 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 8.9E-43 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS42270 f18c16488c1fbd0c49b6583a777f917c 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 8.9E-43 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS42270 f18c16488c1fbd0c49b6583a777f917c 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 8.9E-43 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS42270 f18c16488c1fbd0c49b6583a777f917c 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 8.9E-43 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS42270 f18c16488c1fbd0c49b6583a777f917c 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 8.9E-43 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS42270 f18c16488c1fbd0c49b6583a777f917c 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 8.9E-43 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS42270 f18c16488c1fbd0c49b6583a777f917c 281 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 147 175 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMALA_RS40775 fbd5ed2862c9e96de88ced2e3157877d 209 Gene3D G3DSA:3.40.50.150 4 202 2.7E-30 T 29-03-2018 SMALA_RS40775 fbd5ed2862c9e96de88ced2e3157877d 209 SUPERFAMILY SSF53335 3 185 1.23E-31 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS40775 fbd5ed2862c9e96de88ced2e3157877d 209 Pfam PF13649 Methyltransferase domain 54 142 1.0E-16 T 29-03-2018 SMALA_RS22740 0c2625a97e4939663c5fce1d70b71b59 147 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 15 146 28.478 T 29-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 SMALA_RS22740 0c2625a97e4939663c5fce1d70b71b59 147 SUPERFAMILY SSF52161 4 144 2.62E-60 T 29-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 SMALA_RS22740 0c2625a97e4939663c5fce1d70b71b59 147 PIRSF PIRSF002181 2 147 3.1E-49 T 29-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 SMALA_RS22740 0c2625a97e4939663c5fce1d70b71b59 147 Gene3D G3DSA:3.90.1180.10 1 147 3.4E-64 T 29-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 SMALA_RS22740 0c2625a97e4939663c5fce1d70b71b59 147 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 7 141 2.6E-61 T 29-03-2018 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS22740 0c2625a97e4939663c5fce1d70b71b59 147 Pfam PF00572 Ribosomal protein L13 14 137 2.1E-57 T 29-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 SMALA_RS22740 0c2625a97e4939663c5fce1d70b71b59 147 ProSitePatterns PS00783 Ribosomal protein L13 signature. 105 127 - T 29-03-2018 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 SMALA_RS32675 f63360b27638647d6ee3b305404f7190 170 SUPERFAMILY SSF46689 3 44 7.62E-6 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS32675 f63360b27638647d6ee3b305404f7190 170 Pfam PF13936 Helix-turn-helix domain 9 39 1.1E-8 T 29-03-2018 IPR025246 Transposase IS30-like HTH domain SMALA_RS32675 f63360b27638647d6ee3b305404f7190 170 Gene3D G3DSA:1.10.10.60 3 41 1.7E-11 T 29-03-2018 SMALA_RS33945 429289578e2f126e2a57b8001e867d0f 300 Pfam PF00753 Metallo-beta-lactamase superfamily 61 273 3.4E-30 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS33945 429289578e2f126e2a57b8001e867d0f 300 SMART SM00849 59 273 9.5E-23 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS33945 429289578e2f126e2a57b8001e867d0f 300 Gene3D G3DSA:3.60.15.10 4 285 1.1E-48 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS33945 429289578e2f126e2a57b8001e867d0f 300 SUPERFAMILY SSF56281 59 287 4.85E-39 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS30220 17b1b0a1f0899c58d7b3b79c895885f1 277 SUPERFAMILY SSF47413 6 52 7.7E-6 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS30220 17b1b0a1f0899c58d7b3b79c895885f1 277 Gene3D G3DSA:1.10.3100.10 4 142 3.7E-8 T 29-03-2018 IPR027910 YdiL-like domain SMALA_RS30220 17b1b0a1f0899c58d7b3b79c895885f1 277 Pfam PF13560 Helix-turn-helix domain 6 61 1.1E-8 T 29-03-2018 SMALA_RS09310 1988b8cfee54f88f6ceea803dd4b357a 446 SUPERFAMILY SSF53850 26 437 5.93E-74 T 29-03-2018 SMALA_RS09310 1988b8cfee54f88f6ceea803dd4b357a 446 Pfam PF01547 Bacterial extracellular solute-binding protein 55 349 6.0E-42 T 29-03-2018 IPR006059 Solute-binding family 1 GO:0006810 SMALA_RS09310 1988b8cfee54f88f6ceea803dd4b357a 446 Gene3D G3DSA:3.40.190.10 28 194 3.1E-38 T 29-03-2018 SMALA_RS09310 1988b8cfee54f88f6ceea803dd4b357a 446 Gene3D G3DSA:3.40.190.10 195 390 7.9E-16 T 29-03-2018 SMALA_RS31315 2fa37a19646241397bdc70a3061aede4 649 Pfam PF01568 Molydopterin dinucleotide binding domain 532 634 2.3E-24 T 29-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 SMALA_RS31315 2fa37a19646241397bdc70a3061aede4 649 Gene3D G3DSA:3.40.50.740 19 190 1.0E-39 T 29-03-2018 SMALA_RS31315 2fa37a19646241397bdc70a3061aede4 649 SUPERFAMILY SSF50692 521 642 1.45E-29 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain SMALA_RS31315 2fa37a19646241397bdc70a3061aede4 649 Gene3D G3DSA:2.40.40.20 488 641 1.4E-32 T 29-03-2018 SMALA_RS31315 2fa37a19646241397bdc70a3061aede4 649 SUPERFAMILY SSF53706 15 497 8.25E-171 T 29-03-2018 SMALA_RS31315 2fa37a19646241397bdc70a3061aede4 649 Pfam PF00384 Molybdopterin oxidoreductase 16 441 6.7E-84 T 29-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS31315 2fa37a19646241397bdc70a3061aede4 649 Gene3D G3DSA:3.40.50.740 191 487 3.6E-86 T 29-03-2018 SMALA_RS32275 fd46dbf09024af7741cd69eb30bca37b 405 PRINTS PR00723 Subtilisin serine protease family (S8) signature 51 70 4.1E-15 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related SMALA_RS32275 fd46dbf09024af7741cd69eb30bca37b 405 PRINTS PR00723 Subtilisin serine protease family (S8) signature 263 279 4.1E-15 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related SMALA_RS32275 fd46dbf09024af7741cd69eb30bca37b 405 PRINTS PR00723 Subtilisin serine protease family (S8) signature 91 104 4.1E-15 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related SMALA_RS32275 fd46dbf09024af7741cd69eb30bca37b 405 Gene3D G3DSA:3.40.50.200 30 338 1.8E-81 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMALA_RS32275 fd46dbf09024af7741cd69eb30bca37b 405 SUPERFAMILY SSF52743 33 324 2.88E-81 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMALA_RS32275 fd46dbf09024af7741cd69eb30bca37b 405 Pfam PF00082 Subtilase family 51 314 1.6E-47 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMALA_RS32275 fd46dbf09024af7741cd69eb30bca37b 405 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 56 67 - T 29-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site SMALA_RS32275 fd46dbf09024af7741cd69eb30bca37b 405 TIGRFAM TIGR03921 T7SS_mycosin: type VII secretion-associated serine protease mycosin 40 381 2.0E-97 T 29-03-2018 IPR023834 Type VII secretion system peptidase S8A, mycosin SMALA_RS20445 41bd409483060146917b6963b9923b1d 120 Pfam PF17269 Family of unknown function (DUF5335) 7 117 3.8E-31 T 29-03-2018 IPR035223 Protein of unknown function DUF5335 SMALA_RS20445 41bd409483060146917b6963b9923b1d 120 ProDom PD072590 AQ_1176 9 111 1.0E-8 T 29-03-2018 IPR035223 Protein of unknown function DUF5335 SMALA_RS15475 574b80b5fd3f0993f662454af8947e2b 175 Gene3D G3DSA:3.40.630.30 5 166 3.5E-15 T 29-03-2018 SMALA_RS15475 574b80b5fd3f0993f662454af8947e2b 175 SUPERFAMILY SSF55729 8 161 1.28E-13 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS15475 574b80b5fd3f0993f662454af8947e2b 175 Pfam PF00583 Acetyltransferase (GNAT) family 17 122 8.3E-5 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SMALA_RS04640 a82c6a1ed7ab34e14588a33803d65cd2 271 PIRSF PIRSF006648 2 266 2.5E-15 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMALA_RS04640 a82c6a1ed7ab34e14588a33803d65cd2 271 Pfam PF01061 ABC-2 type transporter 27 232 2.5E-18 T 29-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 SMALA_RS19060 13fadb6fce2c5bbe243393d156359054 276 PRINTS PR00046 Major sigma-70 factor signature 79 92 2.3E-10 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS19060 13fadb6fce2c5bbe243393d156359054 276 PRINTS PR00046 Major sigma-70 factor signature 243 258 2.3E-10 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS19060 13fadb6fce2c5bbe243393d156359054 276 PRINTS PR00046 Major sigma-70 factor signature 226 238 2.3E-10 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS19060 13fadb6fce2c5bbe243393d156359054 276 SUPERFAMILY SSF88659 128 203 6.1E-15 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS19060 13fadb6fce2c5bbe243393d156359054 276 SUPERFAMILY SSF88946 18 124 5.97E-31 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS19060 13fadb6fce2c5bbe243393d156359054 276 Gene3D G3DSA:1.10.601.10 26 123 5.1E-24 T 29-03-2018 SMALA_RS19060 13fadb6fce2c5bbe243393d156359054 276 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 51 272 1.4E-95 T 29-03-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS19060 13fadb6fce2c5bbe243393d156359054 276 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 79 92 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS19060 13fadb6fce2c5bbe243393d156359054 276 Gene3D G3DSA:1.10.10.10 125 176 1.5E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS19060 13fadb6fce2c5bbe243393d156359054 276 Pfam PF04539 Sigma-70 region 3 136 201 2.4E-12 T 29-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS19060 13fadb6fce2c5bbe243393d156359054 276 SUPERFAMILY SSF88659 191 273 1.35E-17 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS19060 13fadb6fce2c5bbe243393d156359054 276 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 52 272 5.2E-36 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS19060 13fadb6fce2c5bbe243393d156359054 276 Pfam PF04542 Sigma-70 region 2 55 124 1.3E-17 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS19060 13fadb6fce2c5bbe243393d156359054 276 Pfam PF04545 Sigma-70, region 4 222 271 1.2E-18 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS19060 13fadb6fce2c5bbe243393d156359054 276 Gene3D G3DSA:1.10.10.10 213 275 1.7E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS37475 26dbe803197fb4a3f97a677aa122b976 151 Pfam PF00027 Cyclic nucleotide-binding domain 26 112 1.2E-11 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain SMALA_RS37475 26dbe803197fb4a3f97a677aa122b976 151 SUPERFAMILY SSF51206 7 142 2.23E-19 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like SMALA_RS37475 26dbe803197fb4a3f97a677aa122b976 151 SMART SM00100 7 125 1.8E-7 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain SMALA_RS37475 26dbe803197fb4a3f97a677aa122b976 151 Gene3D G3DSA:2.60.120.10 6 144 1.1E-15 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SMALA_RS14740 2b811f1314dff56865a67fb0a63c9e46 381 SUPERFAMILY SSF53901 185 379 1.69E-49 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS14740 2b811f1314dff56865a67fb0a63c9e46 381 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 223 334 6.3E-26 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS14740 2b811f1314dff56865a67fb0a63c9e46 381 SUPERFAMILY SSF53901 5 215 1.07E-32 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS14740 2b811f1314dff56865a67fb0a63c9e46 381 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 5 214 7.8E-18 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS14740 2b811f1314dff56865a67fb0a63c9e46 381 Gene3D G3DSA:3.40.47.10 229 379 6.8E-41 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS14740 2b811f1314dff56865a67fb0a63c9e46 381 SMART SM00825 Beta-ketoacyl synthase 9 381 2.5E-11 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS14740 2b811f1314dff56865a67fb0a63c9e46 381 Gene3D G3DSA:3.40.47.10 3 228 1.0E-31 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS33875 d82c798db6cabb30d53e824b62573330 339 Pfam PF13377 Periplasmic binding protein-like domain 169 332 1.2E-36 T 29-03-2018 SMALA_RS33875 d82c798db6cabb30d53e824b62573330 339 Gene3D G3DSA:3.40.50.2300 54 174 1.8E-38 T 29-03-2018 SMALA_RS33875 d82c798db6cabb30d53e824b62573330 339 SUPERFAMILY SSF53822 61 335 1.92E-70 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SMALA_RS33875 d82c798db6cabb30d53e824b62573330 339 Gene3D G3DSA:1.10.260.40 1 53 7.1E-20 T 29-03-2018 SMALA_RS33875 d82c798db6cabb30d53e824b62573330 339 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 29-03-2018 SMALA_RS33875 d82c798db6cabb30d53e824b62573330 339 SUPERFAMILY SSF47413 1 59 1.22E-15 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS33875 d82c798db6cabb30d53e824b62573330 339 Gene3D G3DSA:3.40.50.2300 175 335 3.2E-43 T 29-03-2018 SMALA_RS33875 d82c798db6cabb30d53e824b62573330 339 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 8.9E-5 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS33875 d82c798db6cabb30d53e824b62573330 339 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 8.9E-5 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS33875 d82c798db6cabb30d53e824b62573330 339 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 47 2.1E-16 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS33875 d82c798db6cabb30d53e824b62573330 339 SMART SM00354 1 71 2.0E-26 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS27075 08e897a987678cd79cecece9e123b098 158 Gene3D G3DSA:1.10.10.10 7 158 6.0E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS27075 08e897a987678cd79cecece9e123b098 158 Pfam PF12802 MarR family 40 100 2.0E-12 T 29-03-2018 SMALA_RS27075 08e897a987678cd79cecece9e123b098 158 SMART SM00347 34 137 4.6E-17 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS27075 08e897a987678cd79cecece9e123b098 158 SUPERFAMILY SSF46785 8 151 3.38E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS24770 da36b7e3b40e0eb8371530d480b02c3e 99 SUPERFAMILY SSF47598 15 69 3.22E-10 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 SMALA_RS24770 da36b7e3b40e0eb8371530d480b02c3e 99 Gene3D G3DSA:1.10.1220.10 15 55 1.9E-16 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 SMALA_RS26450 0614989b43009753f874ceb7f97fcbab 131 SUPERFAMILY SSF109770 15 130 3.79E-54 T 29-03-2018 IPR014123 Superoxide dismutase, Nickel-type GO:0004784|GO:0016151|GO:0016209 MetaCyc: PWY-6854 SMALA_RS26450 0614989b43009753f874ceb7f97fcbab 131 Gene3D G3DSA:1.20.120.400 15 129 3.6E-41 T 29-03-2018 IPR014123 Superoxide dismutase, Nickel-type GO:0004784|GO:0016151|GO:0016209 MetaCyc: PWY-6854 SMALA_RS26450 0614989b43009753f874ceb7f97fcbab 131 TIGRFAM TIGR02753 sodN: superoxide dismutase, Ni 1 130 6.6E-57 T 29-03-2018 IPR014123 Superoxide dismutase, Nickel-type GO:0004784|GO:0016151|GO:0016209 MetaCyc: PWY-6854 SMALA_RS26450 0614989b43009753f874ceb7f97fcbab 131 Pfam PF09055 Nickel-containing superoxide dismutase 11 129 6.2E-44 T 29-03-2018 IPR014123 Superoxide dismutase, Nickel-type GO:0004784|GO:0016151|GO:0016209 MetaCyc: PWY-6854 SMALA_RS17215 1110b637dbe4c14ee6906b81e76f88c5 386 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 231 365 1.0E-32 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMALA_RS17215 1110b637dbe4c14ee6906b81e76f88c5 386 SUPERFAMILY SSF47203 227 384 6.12E-41 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMALA_RS17215 1110b637dbe4c14ee6906b81e76f88c5 386 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 10 116 9.1E-25 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS17215 1110b637dbe4c14ee6906b81e76f88c5 386 Gene3D G3DSA:1.10.540.10 2 119 4.5E-27 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS17215 1110b637dbe4c14ee6906b81e76f88c5 386 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 121 216 3.9E-19 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 SMALA_RS17215 1110b637dbe4c14ee6906b81e76f88c5 386 PIRSF PIRSF016578 236 385 3.5E-8 T 29-03-2018 SMALA_RS17215 1110b637dbe4c14ee6906b81e76f88c5 386 PIRSF PIRSF016578 1 197 2.1E-10 T 29-03-2018 SMALA_RS17215 1110b637dbe4c14ee6906b81e76f88c5 386 Gene3D G3DSA:1.20.140.10 218 386 1.7E-41 T 29-03-2018 SMALA_RS17215 1110b637dbe4c14ee6906b81e76f88c5 386 SUPERFAMILY SSF56645 10 242 9.16E-59 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMALA_RS17215 1110b637dbe4c14ee6906b81e76f88c5 386 Gene3D G3DSA:2.40.110.10 120 217 5.7E-27 T 29-03-2018 SMALA_RS10560 d8cae7e06a099f9df81eee20dd00627c 320 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 210 280 1.1E-17 T 29-03-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMALA_RS10560 d8cae7e06a099f9df81eee20dd00627c 320 TIGRFAM TIGR02866 CoxB: cytochrome c oxidase, subunit II 52 289 1.2E-46 T 29-03-2018 IPR014222 Cytochrome c oxidase, subunit II GO:0016021|GO:0016491 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMALA_RS10560 d8cae7e06a099f9df81eee20dd00627c 320 Gene3D G3DSA:1.10.287.90 41 126 1.9E-17 T 29-03-2018 SMALA_RS10560 d8cae7e06a099f9df81eee20dd00627c 320 PRINTS PR01166 Cytochrome c oxidase subunit II signature 263 280 8.6E-15 T 29-03-2018 SMALA_RS10560 d8cae7e06a099f9df81eee20dd00627c 320 PRINTS PR01166 Cytochrome c oxidase subunit II signature 99 111 8.6E-15 T 29-03-2018 SMALA_RS10560 d8cae7e06a099f9df81eee20dd00627c 320 PRINTS PR01166 Cytochrome c oxidase subunit II signature 245 262 8.6E-15 T 29-03-2018 SMALA_RS10560 d8cae7e06a099f9df81eee20dd00627c 320 PRINTS PR01166 Cytochrome c oxidase subunit II signature 134 153 8.6E-15 T 29-03-2018 SMALA_RS10560 d8cae7e06a099f9df81eee20dd00627c 320 PRINTS PR01166 Cytochrome c oxidase subunit II signature 225 245 8.6E-15 T 29-03-2018 SMALA_RS10560 d8cae7e06a099f9df81eee20dd00627c 320 SUPERFAMILY SSF81464 27 124 4.58E-18 T 29-03-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMALA_RS10560 d8cae7e06a099f9df81eee20dd00627c 320 SUPERFAMILY SSF49503 131 157 4.2E-41 T 29-03-2018 IPR008972 Cupredoxin SMALA_RS10560 d8cae7e06a099f9df81eee20dd00627c 320 SUPERFAMILY SSF49503 203 299 4.2E-41 T 29-03-2018 IPR008972 Cupredoxin SMALA_RS10560 d8cae7e06a099f9df81eee20dd00627c 320 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 226 274 - T 29-03-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMALA_RS10560 d8cae7e06a099f9df81eee20dd00627c 320 Gene3D G3DSA:2.60.40.420 127 320 5.9E-46 T 29-03-2018 IPR008972 Cupredoxin SMALA_RS05655 e642ad565b36aabae9f9e9a5958f2bad 375 PIRSF PIRSF037226 1 373 2.0E-132 T 29-03-2018 IPR017144 Peptidase M20A, amidohydrolase, predicted SMALA_RS05655 e642ad565b36aabae9f9e9a5958f2bad 375 Pfam PF01546 Peptidase family M20/M25/M40 83 343 1.5E-7 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 SMALA_RS05655 e642ad565b36aabae9f9e9a5958f2bad 375 Gene3D G3DSA:3.40.630.10 2 374 1.1E-53 T 29-03-2018 SMALA_RS05655 e642ad565b36aabae9f9e9a5958f2bad 375 SUPERFAMILY SSF53187 8 180 1.66E-58 T 29-03-2018 SMALA_RS05655 e642ad565b36aabae9f9e9a5958f2bad 375 SUPERFAMILY SSF53187 280 371 1.66E-58 T 29-03-2018 SMALA_RS05655 e642ad565b36aabae9f9e9a5958f2bad 375 Pfam PF07687 Peptidase dimerisation domain 170 258 1.0E-4 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain SMALA_RS05655 e642ad565b36aabae9f9e9a5958f2bad 375 SUPERFAMILY SSF55031 170 273 1.26E-20 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain SMALA_RS05655 e642ad565b36aabae9f9e9a5958f2bad 375 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 20 350 6.4E-57 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 SMALA_RS41955 1c1af38cf5196e9d84864c8b123f9b19 431 Gene3D G3DSA:3.40.50.720 5 148 3.6E-8 T 29-03-2018 SMALA_RS41955 1c1af38cf5196e9d84864c8b123f9b19 431 Pfam PF01266 FAD dependent oxidoreductase 6 383 2.0E-51 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 SMALA_RS41955 1c1af38cf5196e9d84864c8b123f9b19 431 Gene3D G3DSA:3.30.9.10 162 345 1.7E-36 T 29-03-2018 SMALA_RS41955 1c1af38cf5196e9d84864c8b123f9b19 431 SUPERFAMILY SSF51905 5 239 1.42E-45 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS41955 1c1af38cf5196e9d84864c8b123f9b19 431 SUPERFAMILY SSF51905 346 402 1.42E-45 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS34975 aa113c728851ee9ee09b275985da5c16 334 TIGRFAM TIGR02778 ligD_pol: DNA ligase D, polymerase domain 14 258 3.2E-73 T 29-03-2018 IPR014145 DNA ligase D, polymerase domain SMALA_RS34975 aa113c728851ee9ee09b275985da5c16 334 Pfam PF01896 DNA primase small subunit 135 255 2.7E-7 T 29-03-2018 IPR002755 DNA primase, small subunit GO:0003896|GO:0006269 Reactome: R-HSA-113501|Reactome: R-HSA-174411|Reactome: R-HSA-174430|Reactome: R-HSA-68952|Reactome: R-HSA-68962|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183 SMALA_RS42345 1b77e21afe72cf0c31e762266ee1d907 728 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 148 671 3.1E-129 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMALA_RS42345 1b77e21afe72cf0c31e762266ee1d907 728 Gene3D G3DSA:3.30.365.10 422 574 4.2E-31 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMALA_RS42345 1b77e21afe72cf0c31e762266ee1d907 728 Gene3D G3DSA:3.30.365.10 256 421 1.3E-32 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMALA_RS42345 1b77e21afe72cf0c31e762266ee1d907 728 Gene3D G3DSA:3.30.365.10 575 728 3.8E-42 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMALA_RS42345 1b77e21afe72cf0c31e762266ee1d907 728 SUPERFAMILY SSF54665 5 144 6.8E-35 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMALA_RS42345 1b77e21afe72cf0c31e762266ee1d907 728 Gene3D G3DSA:3.30.365.10 149 255 2.0E-33 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMALA_RS42345 1b77e21afe72cf0c31e762266ee1d907 728 SUPERFAMILY SSF56003 123 727 1.44E-160 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMALA_RS42345 1b77e21afe72cf0c31e762266ee1d907 728 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 22 130 6.9E-20 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMALA_RS42345 1b77e21afe72cf0c31e762266ee1d907 728 Gene3D G3DSA:3.90.1170.50 2 131 1.7E-30 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMALA_RS42345 1b77e21afe72cf0c31e762266ee1d907 728 SMART SM01008 22 131 2.1E-36 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMALA_RS27285 b25452e652aeb271386fd3c0f0ccfd26 540 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 423 534 1.9E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS27285 b25452e652aeb271386fd3c0f0ccfd26 540 Pfam PF17203 Single cache domain 3 37 171 2.8E-31 T 29-03-2018 IPR033463 Single cache domain 3 SMALA_RS27285 b25452e652aeb271386fd3c0f0ccfd26 540 Gene3D G3DSA:1.10.287.130 320 376 1.4E-14 T 29-03-2018 SMALA_RS27285 b25452e652aeb271386fd3c0f0ccfd26 540 SUPERFAMILY SSF55874 393 535 3.01E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS27285 b25452e652aeb271386fd3c0f0ccfd26 540 SMART SM00387 420 535 5.3E-23 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS27285 b25452e652aeb271386fd3c0f0ccfd26 540 Gene3D G3DSA:3.30.450.20 35 174 8.7E-27 T 29-03-2018 SMALA_RS27285 b25452e652aeb271386fd3c0f0ccfd26 540 Gene3D G3DSA:3.30.450.20 202 319 6.4E-12 T 29-03-2018 SMALA_RS27285 b25452e652aeb271386fd3c0f0ccfd26 540 SUPERFAMILY SSF103190 38 171 1.88E-32 T 29-03-2018 IPR029151 Periplasmic sensor domain-like SMALA_RS27285 b25452e652aeb271386fd3c0f0ccfd26 540 SUPERFAMILY SSF55785 208 311 1.02E-5 T 29-03-2018 IPR000014 PAS domain SMALA_RS27285 b25452e652aeb271386fd3c0f0ccfd26 540 Gene3D G3DSA:3.30.565.10 380 539 5.0E-30 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS27285 b25452e652aeb271386fd3c0f0ccfd26 540 PRINTS PR00344 Bacterial sensor protein C-terminal signature 519 532 2.4E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS27285 b25452e652aeb271386fd3c0f0ccfd26 540 PRINTS PR00344 Bacterial sensor protein C-terminal signature 466 480 2.4E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS27285 b25452e652aeb271386fd3c0f0ccfd26 540 PRINTS PR00344 Bacterial sensor protein C-terminal signature 495 513 2.4E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS08425 a969709c9d51777a8114dff2128b3ef4 240 PRINTS PR00096 Glutamine amidotransferase superfamily signature 172 185 9.2E-5 T 29-03-2018 SMALA_RS08425 a969709c9d51777a8114dff2128b3ef4 240 PRINTS PR00096 Glutamine amidotransferase superfamily signature 81 92 9.2E-5 T 29-03-2018 SMALA_RS08425 a969709c9d51777a8114dff2128b3ef4 240 Gene3D G3DSA:3.40.50.880 2 233 2.3E-42 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS08425 a969709c9d51777a8114dff2128b3ef4 240 SUPERFAMILY SSF52317 4 194 2.72E-41 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS08425 a969709c9d51777a8114dff2128b3ef4 240 Pfam PF00117 Glutamine amidotransferase class-I 43 180 7.1E-21 T 29-03-2018 IPR017926 Glutamine amidotransferase SMALA_RS15585 1afd0a779c0d9e222ec5e94e8d301876 593 Pfam PF17101 Stealth protein CR1, conserved region 1 267 291 2.6E-14 T 29-03-2018 IPR031358 Stealth protein CR1, conserved region 1 SMALA_RS15585 1afd0a779c0d9e222ec5e94e8d301876 593 Pfam PF11380 Stealth protein CR2, conserved region 2 304 409 6.8E-46 T 29-03-2018 IPR021520 Stealth protein CR2, conserved region 2 GO:0016772 SMALA_RS15585 1afd0a779c0d9e222ec5e94e8d301876 593 Pfam PF17103 Stealth protein CR4, conserved region 4 530 581 1.7E-12 T 29-03-2018 IPR031356 Stealth protein CR4, conserved region 4 SMALA_RS15585 1afd0a779c0d9e222ec5e94e8d301876 593 Pfam PF17102 Stealth protein CR3, conserved region 3 454 501 9.1E-18 T 29-03-2018 IPR031357 Stealth protein CR3, conserved region 3 SMALA_RS04590 a820589425cebe8f4ca672b5bbb0b356 447 SUPERFAMILY SSF75005 190 427 9.77E-20 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain SMALA_RS04590 a820589425cebe8f4ca672b5bbb0b356 447 SUPERFAMILY SSF75005 102 153 9.77E-20 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain SMALA_RS04590 a820589425cebe8f4ca672b5bbb0b356 447 Gene3D G3DSA:2.115.10.20 163 432 7.7E-21 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain SMALA_RS04590 a820589425cebe8f4ca672b5bbb0b356 447 Gene3D G3DSA:2.115.10.20 87 162 0.21 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain SMALA_RS04590 a820589425cebe8f4ca672b5bbb0b356 447 Pfam PF04616 Glycosyl hydrolases family 43 188 402 2.2E-15 T 29-03-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 SMALA_RS03035 3889fe41793b418b1afae99da52bdceb 484 Pfam PF00144 Beta-lactamase 38 302 6.0E-41 T 29-03-2018 IPR001466 Beta-lactamase-related SMALA_RS03035 3889fe41793b418b1afae99da52bdceb 484 SUPERFAMILY SSF56601 3 321 2.82E-78 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMALA_RS03035 3889fe41793b418b1afae99da52bdceb 484 Gene3D G3DSA:3.40.710.10 15 318 2.4E-57 T 29-03-2018 SMALA_RS38930 db38d56613e6ebf5d8da7f2748cf6476 367 SUPERFAMILY SSF56281 141 269 2.77E-10 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS38930 db38d56613e6ebf5d8da7f2748cf6476 367 Gene3D G3DSA:3.60.15.10 78 327 3.1E-10 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS18995 5dd838492edb652553415dd9601dd8a4 426 SUPERFAMILY SSF48264 15 413 8.64E-87 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS18995 5dd838492edb652553415dd9601dd8a4 426 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 357 366 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMALA_RS18995 5dd838492edb652553415dd9601dd8a4 426 PRINTS PR00359 B-class P450 signature 207 229 9.3E-54 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS18995 5dd838492edb652553415dd9601dd8a4 426 PRINTS PR00359 B-class P450 signature 306 333 9.3E-54 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS18995 5dd838492edb652553415dd9601dd8a4 426 PRINTS PR00359 B-class P450 signature 334 349 9.3E-54 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS18995 5dd838492edb652553415dd9601dd8a4 426 PRINTS PR00359 B-class P450 signature 159 174 9.3E-54 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS18995 5dd838492edb652553415dd9601dd8a4 426 PRINTS PR00359 B-class P450 signature 142 158 9.3E-54 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS18995 5dd838492edb652553415dd9601dd8a4 426 PRINTS PR00359 B-class P450 signature 355 364 9.3E-54 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS18995 5dd838492edb652553415dd9601dd8a4 426 PRINTS PR00359 B-class P450 signature 92 103 9.3E-54 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS18995 5dd838492edb652553415dd9601dd8a4 426 PRINTS PR00359 B-class P450 signature 288 299 9.3E-54 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS18995 5dd838492edb652553415dd9601dd8a4 426 PRINTS PR00359 B-class P450 signature 364 375 9.3E-54 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS18995 5dd838492edb652553415dd9601dd8a4 426 PRINTS PR00385 P450 superfamily signature 355 364 4.2E-6 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS18995 5dd838492edb652553415dd9601dd8a4 426 PRINTS PR00385 P450 superfamily signature 364 375 4.2E-6 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS18995 5dd838492edb652553415dd9601dd8a4 426 PRINTS PR00385 P450 superfamily signature 253 270 4.2E-6 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS18995 5dd838492edb652553415dd9601dd8a4 426 PRINTS PR00385 P450 superfamily signature 288 299 4.2E-6 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS18995 5dd838492edb652553415dd9601dd8a4 426 Pfam PF00067 Cytochrome P450 93 386 9.8E-27 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS18995 5dd838492edb652553415dd9601dd8a4 426 Gene3D G3DSA:1.10.630.10 1 415 3.5E-74 T 29-03-2018 SMALA_RS14110 0ee57aa8de61a49a479b156fdb7c832b 1312 SUPERFAMILY SSF90123 740 1049 2.35E-74 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMALA_RS14110 0ee57aa8de61a49a479b156fdb7c832b 1312 Pfam PF00005 ABC transporter 376 525 3.6E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS14110 0ee57aa8de61a49a479b156fdb7c832b 1312 Pfam PF00005 ABC transporter 1085 1233 7.5E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS14110 0ee57aa8de61a49a479b156fdb7c832b 1312 ProSitePatterns PS00211 ABC transporters family signature. 497 511 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS14110 0ee57aa8de61a49a479b156fdb7c832b 1312 SMART SM00382 1093 1279 4.3E-20 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS14110 0ee57aa8de61a49a479b156fdb7c832b 1312 SMART SM00382 385 571 5.6E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS14110 0ee57aa8de61a49a479b156fdb7c832b 1312 Pfam PF00664 ABC transporter transmembrane region 752 1022 1.7E-40 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMALA_RS14110 0ee57aa8de61a49a479b156fdb7c832b 1312 Pfam PF00664 ABC transporter transmembrane region 45 313 2.1E-33 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMALA_RS14110 0ee57aa8de61a49a479b156fdb7c832b 1312 SUPERFAMILY SSF52540 1060 1302 1.49E-84 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS14110 0ee57aa8de61a49a479b156fdb7c832b 1312 Gene3D G3DSA:1.20.1560.10 7 345 2.5E-61 T 29-03-2018 SMALA_RS14110 0ee57aa8de61a49a479b156fdb7c832b 1312 Gene3D G3DSA:1.20.1560.10 721 1053 1.4E-64 T 29-03-2018 SMALA_RS14110 0ee57aa8de61a49a479b156fdb7c832b 1312 Gene3D G3DSA:3.40.50.300 1054 1307 8.4E-72 T 29-03-2018 SMALA_RS14110 0ee57aa8de61a49a479b156fdb7c832b 1312 Gene3D G3DSA:3.40.50.300 346 600 6.1E-71 T 29-03-2018 SMALA_RS14110 0ee57aa8de61a49a479b156fdb7c832b 1312 SUPERFAMILY SSF52540 355 592 2.88E-85 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS14110 0ee57aa8de61a49a479b156fdb7c832b 1312 SUPERFAMILY SSF90123 31 347 4.45E-70 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMALA_RS12865 c0be984ba0d7f9e0e96e62f8f059c543 742 Pfam PF03176 MMPL family 484 697 2.0E-40 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 SMALA_RS12865 c0be984ba0d7f9e0e96e62f8f059c543 742 Pfam PF03176 MMPL family 66 387 2.9E-68 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 SMALA_RS12865 c0be984ba0d7f9e0e96e62f8f059c543 742 SUPERFAMILY SSF82866 485 696 1.02E-27 T 29-03-2018 SMALA_RS12865 c0be984ba0d7f9e0e96e62f8f059c543 742 Gene3D G3DSA:1.20.1640.10 487 693 6.6E-29 T 29-03-2018 SMALA_RS12865 c0be984ba0d7f9e0e96e62f8f059c543 742 Gene3D G3DSA:1.20.1640.10 136 354 7.0E-36 T 29-03-2018 SMALA_RS12865 c0be984ba0d7f9e0e96e62f8f059c543 742 SUPERFAMILY SSF82866 157 357 1.44E-34 T 29-03-2018 SMALA_RS01755 6f37711ab4e2f405a1d638db91401f54 577 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 126 136 - T 29-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 SMALA_RS01755 6f37711ab4e2f405a1d638db91401f54 577 SUPERFAMILY SSF52016 379 564 5.81E-55 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel SMALA_RS01755 6f37711ab4e2f405a1d638db91401f54 577 Pfam PF00920 Dehydratase family 43 558 6.5E-183 T 29-03-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 SMALA_RS01755 6f37711ab4e2f405a1d638db91401f54 577 SUPERFAMILY SSF143975 8 377 2.09E-125 T 29-03-2018 SMALA_RS02910 9e528602ef04dfa08d404b3d07e53bed 437 Gene3D G3DSA:1.20.5.100 198 224 3.7E-10 T 29-03-2018 SMALA_RS02910 9e528602ef04dfa08d404b3d07e53bed 437 SMART SM00984 315 416 2.9E-40 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 SMALA_RS02910 9e528602ef04dfa08d404b3d07e53bed 437 PIRSF PIRSF000124 4 431 4.2E-124 T 29-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 SMALA_RS02910 9e528602ef04dfa08d404b3d07e53bed 437 SUPERFAMILY SSF51735 4 187 1.62E-51 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS02910 9e528602ef04dfa08d404b3d07e53bed 437 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 198 288 5.2E-34 T 29-03-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 SMALA_RS02910 9e528602ef04dfa08d404b3d07e53bed 437 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 315 416 6.1E-28 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 SMALA_RS02910 9e528602ef04dfa08d404b3d07e53bed 437 Gene3D G3DSA:3.40.50.720 2 188 7.0E-57 T 29-03-2018 SMALA_RS02910 9e528602ef04dfa08d404b3d07e53bed 437 SUPERFAMILY SSF48179 198 292 4.25E-30 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMALA_RS02910 9e528602ef04dfa08d404b3d07e53bed 437 Gene3D G3DSA:3.40.50.720 227 437 9.3E-71 T 29-03-2018 SMALA_RS02910 9e528602ef04dfa08d404b3d07e53bed 437 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 5 179 3.2E-56 T 29-03-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 SMALA_RS02910 9e528602ef04dfa08d404b3d07e53bed 437 SUPERFAMILY SSF52413 307 424 9.81E-32 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 SMALA_RS02910 9e528602ef04dfa08d404b3d07e53bed 437 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 5 412 6.8E-128 T 29-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 SMALA_RS02910 9e528602ef04dfa08d404b3d07e53bed 437 PIRSF PIRSF500134 4 434 1.4E-146 T 29-03-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 SMALA_RS35870 007523b7ceb62d07037e222baea958f8 256 Gene3D G3DSA:3.30.950.10 121 234 5.2E-21 T 29-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMALA_RS35870 007523b7ceb62d07037e222baea958f8 256 SUPERFAMILY SSF53790 2 233 6.02E-62 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMALA_RS35870 007523b7ceb62d07037e222baea958f8 256 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 6 20 - T 29-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 SMALA_RS35870 007523b7ceb62d07037e222baea958f8 256 TIGRFAM TIGR01465 cobM_cbiF: precorrin-4 C11-methyltransferase 3 244 1.3E-88 T 29-03-2018 IPR006362 Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase GO:0009236|GO:0046026 SMALA_RS35870 007523b7ceb62d07037e222baea958f8 256 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 76 109 - T 29-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 SMALA_RS35870 007523b7ceb62d07037e222baea958f8 256 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 2 208 7.3E-41 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMALA_RS35870 007523b7ceb62d07037e222baea958f8 256 Gene3D G3DSA:3.40.1010.10 1 120 4.5E-32 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMALA_RS15905 f2d9cef65d71b64bd482d59a6c46b4d3 546 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 375 526 2.0E-15 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 SMALA_RS15905 f2d9cef65d71b64bd482d59a6c46b4d3 546 SUPERFAMILY SSF55846 351 537 5.61E-46 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 SMALA_RS15905 f2d9cef65d71b64bd482d59a6c46b4d3 546 Gene3D G3DSA:3.40.80.10 340 546 5.1E-45 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 SMALA_RS15905 f2d9cef65d71b64bd482d59a6c46b4d3 546 SMART SM00701 351 499 7.1E-53 T 29-03-2018 IPR006619 Peptidoglycan recognition protein family domain, metazoa/bacteria GO:0008270|GO:0008745|GO:0009253 Reactome: R-HSA-6803157 SMALA_RS31595 478096594df26c79a9748a944a862c6d 435 Gene3D G3DSA:1.20.200.10 127 394 2.4E-58 T 29-03-2018 SMALA_RS31595 478096594df26c79a9748a944a862c6d 435 Gene3D G3DSA:1.10.275.10 5 126 9.6E-32 T 29-03-2018 IPR024083 Fumarase/histidase, N-terminal SMALA_RS31595 478096594df26c79a9748a944a862c6d 435 SUPERFAMILY SSF48557 11 413 2.04E-94 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 SMALA_RS31595 478096594df26c79a9748a944a862c6d 435 PRINTS PR00149 Fumarate lyase superfamily signature 167 185 5.7E-21 T 29-03-2018 IPR000362 Fumarate lyase family SMALA_RS31595 478096594df26c79a9748a944a862c6d 435 PRINTS PR00149 Fumarate lyase superfamily signature 304 320 5.7E-21 T 29-03-2018 IPR000362 Fumarate lyase family SMALA_RS31595 478096594df26c79a9748a944a862c6d 435 PRINTS PR00149 Fumarate lyase superfamily signature 258 285 5.7E-21 T 29-03-2018 IPR000362 Fumarate lyase family SMALA_RS31595 478096594df26c79a9748a944a862c6d 435 PRINTS PR00149 Fumarate lyase superfamily signature 122 140 5.7E-21 T 29-03-2018 IPR000362 Fumarate lyase family SMALA_RS31595 478096594df26c79a9748a944a862c6d 435 Pfam PF00206 Lyase 9 329 2.5E-69 T 29-03-2018 IPR022761 Fumarate lyase, N-terminal SMALA_RS31595 478096594df26c79a9748a944a862c6d 435 ProSitePatterns PS00163 Fumarate lyases signature. 304 313 - T 29-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 SMALA_RS18880 4ff02f255ed8f3213ed8116d3c27ba54 261 Gene3D G3DSA:1.10.10.10 9 84 3.9E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS18880 4ff02f255ed8f3213ed8116d3c27ba54 261 Gene3D G3DSA:3.40.1410.10 88 256 4.4E-43 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMALA_RS18880 4ff02f255ed8f3213ed8116d3c27ba54 261 Pfam PF07702 UTRA domain 115 252 3.2E-30 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMALA_RS18880 4ff02f255ed8f3213ed8116d3c27ba54 261 SMART SM00866 114 253 2.6E-24 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMALA_RS18880 4ff02f255ed8f3213ed8116d3c27ba54 261 SUPERFAMILY SSF64288 70 258 4.24E-34 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMALA_RS18880 4ff02f255ed8f3213ed8116d3c27ba54 261 SUPERFAMILY SSF46785 11 94 1.44E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS18880 4ff02f255ed8f3213ed8116d3c27ba54 261 SMART SM00345 23 82 8.6E-24 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS18880 4ff02f255ed8f3213ed8116d3c27ba54 261 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 56 5.0E-10 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS18880 4ff02f255ed8f3213ed8116d3c27ba54 261 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 56 72 5.0E-10 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS18880 4ff02f255ed8f3213ed8116d3c27ba54 261 Pfam PF00392 Bacterial regulatory proteins, gntR family 21 82 5.5E-23 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS40990 26264bdf4f8bf22cc56edd096af29347 273 Pfam PF12697 Alpha/beta hydrolase family 21 243 4.8E-14 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS40990 26264bdf4f8bf22cc56edd096af29347 273 Gene3D G3DSA:3.40.50.1820 7 257 2.7E-28 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS40990 26264bdf4f8bf22cc56edd096af29347 273 SUPERFAMILY SSF53474 14 255 1.03E-28 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS30625 d918113e8c6af17f9576513895d59c43 255 Gene3D G3DSA:3.40.1410.10 98 249 7.3E-46 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMALA_RS30625 d918113e8c6af17f9576513895d59c43 255 Pfam PF00392 Bacterial regulatory proteins, gntR family 26 88 3.3E-16 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS30625 d918113e8c6af17f9576513895d59c43 255 Pfam PF07702 UTRA domain 109 245 6.4E-38 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMALA_RS30625 d918113e8c6af17f9576513895d59c43 255 SUPERFAMILY SSF46785 18 92 6.29E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS30625 d918113e8c6af17f9576513895d59c43 255 Gene3D G3DSA:1.10.10.10 11 97 1.3E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS30625 d918113e8c6af17f9576513895d59c43 255 SUPERFAMILY SSF64288 76 250 3.3E-46 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMALA_RS30625 d918113e8c6af17f9576513895d59c43 255 SMART SM00345 29 88 7.9E-15 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS30625 d918113e8c6af17f9576513895d59c43 255 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 62 1.5E-6 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS30625 d918113e8c6af17f9576513895d59c43 255 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 62 78 1.5E-6 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS30625 d918113e8c6af17f9576513895d59c43 255 SMART SM00866 108 246 1.9E-35 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMALA_RS33655 74069808b6163745a8c35aeb7e21cfd1 336 Gene3D G3DSA:3.90.25.10 250 335 2.3E-20 T 29-03-2018 SMALA_RS33655 74069808b6163745a8c35aeb7e21cfd1 336 Gene3D G3DSA:3.40.50.720 1 249 1.6E-50 T 29-03-2018 SMALA_RS33655 74069808b6163745a8c35aeb7e21cfd1 336 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 1 332 1.4E-123 T 29-03-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-70370 SMALA_RS33655 74069808b6163745a8c35aeb7e21cfd1 336 SUPERFAMILY SSF51735 1 331 9.92E-91 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS33655 74069808b6163745a8c35aeb7e21cfd1 336 Pfam PF01370 NAD dependent epimerase/dehydratase family 1 260 1.7E-62 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 SMALA_RS03105 764a5b281cceeaa20ab65131f75c1f60 399 SUPERFAMILY SSF51905 4 170 2.27E-58 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS03105 764a5b281cceeaa20ab65131f75c1f60 399 SUPERFAMILY SSF51905 264 371 2.27E-58 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS03105 764a5b281cceeaa20ab65131f75c1f60 399 Pfam PF01494 FAD binding domain 7 341 1.2E-27 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 SMALA_RS03105 764a5b281cceeaa20ab65131f75c1f60 399 Gene3D G3DSA:3.50.50.60 1 368 1.6E-45 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS03105 764a5b281cceeaa20ab65131f75c1f60 399 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 326 342 1.8E-23 T 29-03-2018 SMALA_RS03105 764a5b281cceeaa20ab65131f75c1f60 399 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 277 292 1.8E-23 T 29-03-2018 SMALA_RS03105 764a5b281cceeaa20ab65131f75c1f60 399 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 1.8E-23 T 29-03-2018 SMALA_RS03105 764a5b281cceeaa20ab65131f75c1f60 399 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 292 308 1.8E-23 T 29-03-2018 SMALA_RS03105 764a5b281cceeaa20ab65131f75c1f60 399 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 149 164 1.8E-23 T 29-03-2018 SMALA_RS30310 763e18654d6a41db42a9ce158eba9c7f 260 SMART SM00824 Thioesterase 40 255 4.6E-66 T 29-03-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 SMALA_RS30310 763e18654d6a41db42a9ce158eba9c7f 260 Gene3D G3DSA:3.40.50.1820 1 259 1.5E-21 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS30310 763e18654d6a41db42a9ce158eba9c7f 260 Pfam PF00975 Thioesterase domain 38 254 4.9E-22 T 29-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 SMALA_RS30310 763e18654d6a41db42a9ce158eba9c7f 260 SUPERFAMILY SSF53474 31 256 1.09E-31 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS06625 bc5475674c64e05914019dc197e6b0e3 166 Pfam PF01613 Flavin reductase like domain 18 160 9.8E-33 T 29-03-2018 IPR002563 Flavin reductase like domain GO:0010181 SMALA_RS06625 bc5475674c64e05914019dc197e6b0e3 166 SMART SM00903 17 160 3.2E-50 T 29-03-2018 IPR002563 Flavin reductase like domain GO:0010181 SMALA_RS06625 bc5475674c64e05914019dc197e6b0e3 166 SUPERFAMILY SSF50475 2 163 3.78E-46 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS06625 bc5475674c64e05914019dc197e6b0e3 166 Gene3D G3DSA:2.30.110.10 5 166 5.6E-41 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS14590 3245cda879749651c49fcbc1be12cfee 315 SUPERFAMILY SSF51735 100 275 3.32E-43 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS14590 3245cda879749651c49fcbc1be12cfee 315 Gene3D G3DSA:3.40.50.720 127 275 3.6E-40 T 29-03-2018 SMALA_RS14590 3245cda879749651c49fcbc1be12cfee 315 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 107 274 2.3E-42 T 29-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 SMALA_RS14590 3245cda879749651c49fcbc1be12cfee 315 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 213 229 - T 29-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site SMALA_RS14590 3245cda879749651c49fcbc1be12cfee 315 SUPERFAMILY SSF52283 5 132 1.02E-6 T 29-03-2018 SMALA_RS14590 3245cda879749651c49fcbc1be12cfee 315 Gene3D G3DSA:3.40.50.720 2 126 2.9E-24 T 29-03-2018 SMALA_RS05530 5a6066435ed6b0d5b3c3f98e662da896 176 Gene3D G3DSA:3.40.50.850 1 176 6.6E-39 T 29-03-2018 SMALA_RS05530 5a6066435ed6b0d5b3c3f98e662da896 176 Pfam PF00857 Isochorismatase family 1 170 1.4E-34 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SMALA_RS05530 5a6066435ed6b0d5b3c3f98e662da896 176 SUPERFAMILY SSF52499 2 176 3.4E-41 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SMALA_RS08585 5f79efe50fa9985cb0df6288b5c928fa 100 Pfam PF05800 Gas vesicle synthesis protein GvpO 16 98 1.5E-29 T 29-03-2018 IPR008634 Gas vesicle protein GvpO GO:0031412 SMALA_RS08585 5f79efe50fa9985cb0df6288b5c928fa 100 PIRSF PIRSF028743 1 100 7.9E-31 T 29-03-2018 IPR008634 Gas vesicle protein GvpO GO:0031412 SMALA_RS02330 37d29ce608b9a2c7c5c0ae93ab87af55 399 PRINTS PR00359 B-class P450 signature 185 207 9.2E-53 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS02330 37d29ce608b9a2c7c5c0ae93ab87af55 399 PRINTS PR00359 B-class P450 signature 145 160 9.2E-53 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS02330 37d29ce608b9a2c7c5c0ae93ab87af55 399 PRINTS PR00359 B-class P450 signature 331 340 9.2E-53 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS02330 37d29ce608b9a2c7c5c0ae93ab87af55 399 PRINTS PR00359 B-class P450 signature 265 276 9.2E-53 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS02330 37d29ce608b9a2c7c5c0ae93ab87af55 399 PRINTS PR00359 B-class P450 signature 340 351 9.2E-53 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS02330 37d29ce608b9a2c7c5c0ae93ab87af55 399 PRINTS PR00359 B-class P450 signature 282 309 9.2E-53 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS02330 37d29ce608b9a2c7c5c0ae93ab87af55 399 PRINTS PR00359 B-class P450 signature 82 93 9.2E-53 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS02330 37d29ce608b9a2c7c5c0ae93ab87af55 399 PRINTS PR00359 B-class P450 signature 128 144 9.2E-53 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS02330 37d29ce608b9a2c7c5c0ae93ab87af55 399 PRINTS PR00359 B-class P450 signature 310 325 9.2E-53 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS02330 37d29ce608b9a2c7c5c0ae93ab87af55 399 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 333 342 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMALA_RS02330 37d29ce608b9a2c7c5c0ae93ab87af55 399 Gene3D G3DSA:1.10.630.10 5 391 1.7E-75 T 29-03-2018 SMALA_RS02330 37d29ce608b9a2c7c5c0ae93ab87af55 399 SUPERFAMILY SSF48264 18 392 2.88E-90 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS02330 37d29ce608b9a2c7c5c0ae93ab87af55 399 Pfam PF00067 Cytochrome P450 173 361 4.1E-17 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS18530 901ee023ea3cb6715451bde8e43089e0 113 Pfam PF01740 STAS domain 8 108 4.6E-18 T 29-03-2018 IPR002645 STAS domain SMALA_RS18530 901ee023ea3cb6715451bde8e43089e0 113 Gene3D G3DSA:3.30.750.24 5 113 2.2E-24 T 29-03-2018 IPR002645 STAS domain SMALA_RS18530 901ee023ea3cb6715451bde8e43089e0 113 SUPERFAMILY SSF52091 3 110 1.96E-31 T 29-03-2018 IPR002645 STAS domain SMALA_RS18530 901ee023ea3cb6715451bde8e43089e0 113 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 3 106 3.9E-33 T 29-03-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 SMALA_RS14395 8910bddbfb8f92aebf6da6251e5609ea 455 ProSitePatterns PS00655 Glycosyl hydrolases family 6 signature 1. 113 129 - T 29-03-2018 IPR001524 Glycoside hydrolase, family 6, conserved site GO:0004553|GO:0005975 SMALA_RS14395 8910bddbfb8f92aebf6da6251e5609ea 455 SUPERFAMILY SSF51989 40 455 1.44E-99 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMALA_RS14395 8910bddbfb8f92aebf6da6251e5609ea 455 Gene3D G3DSA:3.20.20.40 39 455 1.4E-141 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMALA_RS14395 8910bddbfb8f92aebf6da6251e5609ea 455 PRINTS PR00733 Glycosyl hydrolase family 6 signature 140 155 2.2E-37 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMALA_RS14395 8910bddbfb8f92aebf6da6251e5609ea 455 PRINTS PR00733 Glycosyl hydrolase family 6 signature 214 227 2.2E-37 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMALA_RS14395 8910bddbfb8f92aebf6da6251e5609ea 455 PRINTS PR00733 Glycosyl hydrolase family 6 signature 317 330 2.2E-37 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMALA_RS14395 8910bddbfb8f92aebf6da6251e5609ea 455 PRINTS PR00733 Glycosyl hydrolase family 6 signature 108 121 2.2E-37 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMALA_RS14395 8910bddbfb8f92aebf6da6251e5609ea 455 PRINTS PR00733 Glycosyl hydrolase family 6 signature 254 264 2.2E-37 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMALA_RS14395 8910bddbfb8f92aebf6da6251e5609ea 455 PRINTS PR00733 Glycosyl hydrolase family 6 signature 358 378 2.2E-37 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMALA_RS14395 8910bddbfb8f92aebf6da6251e5609ea 455 PRINTS PR00733 Glycosyl hydrolase family 6 signature 381 395 2.2E-37 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMALA_RS14395 8910bddbfb8f92aebf6da6251e5609ea 455 PRINTS PR00733 Glycosyl hydrolase family 6 signature 58 77 2.2E-37 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMALA_RS14395 8910bddbfb8f92aebf6da6251e5609ea 455 PIRSF PIRSF001100 6 455 3.2E-97 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMALA_RS14395 8910bddbfb8f92aebf6da6251e5609ea 455 Pfam PF01341 Glycosyl hydrolases family 6 59 404 2.9E-90 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMALA_RS31630 093cc122a94893a10d89c62d5586df84 285 PRINTS PR01438 Universal stress protein signature 243 255 1.3E-6 T 29-03-2018 IPR006015 Universal stress protein A SMALA_RS31630 093cc122a94893a10d89c62d5586df84 285 PRINTS PR01438 Universal stress protein signature 2 20 1.3E-6 T 29-03-2018 IPR006015 Universal stress protein A SMALA_RS31630 093cc122a94893a10d89c62d5586df84 285 PRINTS PR01438 Universal stress protein signature 261 283 1.3E-6 T 29-03-2018 IPR006015 Universal stress protein A SMALA_RS31630 093cc122a94893a10d89c62d5586df84 285 Gene3D G3DSA:3.40.50.620 141 285 1.9E-23 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS31630 093cc122a94893a10d89c62d5586df84 285 Gene3D G3DSA:3.40.50.620 2 139 1.7E-21 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS31630 093cc122a94893a10d89c62d5586df84 285 SUPERFAMILY SSF52402 146 284 6.03E-21 T 29-03-2018 SMALA_RS31630 093cc122a94893a10d89c62d5586df84 285 SUPERFAMILY SSF52402 6 138 3.35E-17 T 29-03-2018 SMALA_RS31630 093cc122a94893a10d89c62d5586df84 285 Pfam PF00582 Universal stress protein family 145 283 3.2E-15 T 29-03-2018 IPR006016 UspA GO:0006950 SMALA_RS31630 093cc122a94893a10d89c62d5586df84 285 Pfam PF00582 Universal stress protein family 3 136 1.3E-12 T 29-03-2018 IPR006016 UspA GO:0006950 SMALA_RS05595 d1fa928a18d519d7c33099047a3dd9dc 405 Gene3D G3DSA:3.40.50.2000 199 359 7.2E-40 T 29-03-2018 SMALA_RS05595 d1fa928a18d519d7c33099047a3dd9dc 405 Gene3D G3DSA:3.40.50.2000 2 198 3.3E-11 T 29-03-2018 SMALA_RS05595 d1fa928a18d519d7c33099047a3dd9dc 405 SUPERFAMILY SSF53756 2 375 5.93E-68 T 29-03-2018 SMALA_RS05595 d1fa928a18d519d7c33099047a3dd9dc 405 Pfam PF13439 Glycosyltransferase Family 4 13 189 2.0E-9 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 SMALA_RS05595 d1fa928a18d519d7c33099047a3dd9dc 405 Pfam PF00534 Glycosyl transferases group 1 196 354 1.8E-38 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 SMALA_RS13980 bc9a70fa2cdf8069c678c5296e22d33e 268 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 25 220 0.0014 T 29-03-2018 SMALA_RS13980 bc9a70fa2cdf8069c678c5296e22d33e 268 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 160 188 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMALA_RS13980 bc9a70fa2cdf8069c678c5296e22d33e 268 Gene3D G3DSA:3.40.50.720 17 57 7.1E-10 T 29-03-2018 SMALA_RS13980 bc9a70fa2cdf8069c678c5296e22d33e 268 Gene3D G3DSA:3.40.50.720 58 268 2.2E-65 T 29-03-2018 SMALA_RS13980 bc9a70fa2cdf8069c678c5296e22d33e 268 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 161 2.5E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS13980 bc9a70fa2cdf8069c678c5296e22d33e 268 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 101 112 2.5E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS13980 bc9a70fa2cdf8069c678c5296e22d33e 268 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 173 192 2.5E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS13980 bc9a70fa2cdf8069c678c5296e22d33e 268 SUPERFAMILY SSF51735 24 266 9.25E-81 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS13980 bc9a70fa2cdf8069c678c5296e22d33e 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 101 112 3.6E-43 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS13980 bc9a70fa2cdf8069c678c5296e22d33e 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 26 43 3.6E-43 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS13980 bc9a70fa2cdf8069c678c5296e22d33e 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 192 3.6E-43 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS13980 bc9a70fa2cdf8069c678c5296e22d33e 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 163 3.6E-43 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS13980 bc9a70fa2cdf8069c678c5296e22d33e 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 194 211 3.6E-43 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS13980 bc9a70fa2cdf8069c678c5296e22d33e 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 230 250 3.6E-43 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS13980 bc9a70fa2cdf8069c678c5296e22d33e 268 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 31 266 1.6E-64 T 29-03-2018 SMALA_RS10755 ba638e6e2f27444d60e7b1a39199fb4b 405 Gene3D G3DSA:3.90.75.10 235 301 2.2E-4 T 29-03-2018 SMALA_RS10755 ba638e6e2f27444d60e7b1a39199fb4b 405 Pfam PF16640 Bacterial Ig-like domain (group 3) 108 195 4.7E-19 T 29-03-2018 IPR032109 Bacterial Ig-like domain (group 3) SMALA_RS10755 ba638e6e2f27444d60e7b1a39199fb4b 405 Pfam PF16640 Bacterial Ig-like domain (group 3) 306 397 1.2E-12 T 29-03-2018 IPR032109 Bacterial Ig-like domain (group 3) SMALA_RS10755 ba638e6e2f27444d60e7b1a39199fb4b 405 Pfam PF16640 Bacterial Ig-like domain (group 3) 208 297 5.1E-21 T 29-03-2018 IPR032109 Bacterial Ig-like domain (group 3) SMALA_RS10755 ba638e6e2f27444d60e7b1a39199fb4b 405 Pfam PF16640 Bacterial Ig-like domain (group 3) 13 99 2.0E-19 T 29-03-2018 IPR032109 Bacterial Ig-like domain (group 3) SMALA_RS10755 ba638e6e2f27444d60e7b1a39199fb4b 405 Gene3D G3DSA:2.60.40.10 1 90 4.4E-4 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS10755 ba638e6e2f27444d60e7b1a39199fb4b 405 Gene3D G3DSA:2.60.40.10 91 187 7.1E-5 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS10755 ba638e6e2f27444d60e7b1a39199fb4b 405 Gene3D G3DSA:2.60.40.10 302 388 0.36 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS02710 3421666c91a117c2151990cea3a9353e 122 Gene3D G3DSA:3.30.43.10 1 88 5.3E-18 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 SMALA_RS02710 3421666c91a117c2151990cea3a9353e 122 Pfam PF01565 FAD binding domain 38 77 3.9E-9 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 SMALA_RS02710 3421666c91a117c2151990cea3a9353e 122 Pfam PF02913 FAD linked oxidases, C-terminal domain 74 118 1.3E-15 T 29-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 SMALA_RS02710 3421666c91a117c2151990cea3a9353e 122 Gene3D G3DSA:1.10.45.10 89 118 2.2E-17 T 29-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 SMALA_RS02710 3421666c91a117c2151990cea3a9353e 122 SUPERFAMILY SSF55103 45 119 5.69E-18 T 29-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 SMALA_RS32420 f103695594d9a3c6ce3f2f38ec7159a5 176 SUPERFAMILY SSF55729 1 169 7.39E-36 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS32420 f103695594d9a3c6ce3f2f38ec7159a5 176 Gene3D G3DSA:3.40.630.30 1 175 1.7E-38 T 29-03-2018 SMALA_RS32420 f103695594d9a3c6ce3f2f38ec7159a5 176 Pfam PF13302 Acetyltransferase (GNAT) domain 9 140 7.4E-17 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SMALA_RS07560 8fb0da801498b545342543dca666e066 281 PRINTS PR00377 Inositol monophosphatase superfamily signature 216 240 7.9E-17 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 SMALA_RS07560 8fb0da801498b545342543dca666e066 281 PRINTS PR00377 Inositol monophosphatase superfamily signature 68 84 7.9E-17 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 SMALA_RS07560 8fb0da801498b545342543dca666e066 281 PRINTS PR00377 Inositol monophosphatase superfamily signature 88 104 7.9E-17 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 SMALA_RS07560 8fb0da801498b545342543dca666e066 281 PRINTS PR00377 Inositol monophosphatase superfamily signature 46 66 7.9E-17 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 SMALA_RS07560 8fb0da801498b545342543dca666e066 281 SUPERFAMILY SSF56655 13 265 5.24E-50 T 29-03-2018 SMALA_RS07560 8fb0da801498b545342543dca666e066 281 Pfam PF00459 Inositol monophosphatase family 12 266 1.8E-33 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 SMALA_RS07560 8fb0da801498b545342543dca666e066 281 Gene3D G3DSA:3.30.540.10 11 164 4.1E-30 T 29-03-2018 SMALA_RS07560 8fb0da801498b545342543dca666e066 281 Gene3D G3DSA:3.40.190.80 165 274 2.2E-11 T 29-03-2018 SMALA_RS12740 856e068c9b2ad6b0eb35496063717bf5 171 Gene3D G3DSA:1.10.10.60 34 54 8.1E-11 T 29-03-2018 SMALA_RS12740 856e068c9b2ad6b0eb35496063717bf5 171 Pfam PF00440 Bacterial regulatory proteins, tetR family 2 46 7.7E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS12740 856e068c9b2ad6b0eb35496063717bf5 171 SUPERFAMILY SSF48498 65 170 5.56E-12 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS12740 856e068c9b2ad6b0eb35496063717bf5 171 Gene3D G3DSA:1.10.10.60 1 33 3.0E-10 T 29-03-2018 SMALA_RS12740 856e068c9b2ad6b0eb35496063717bf5 171 SUPERFAMILY SSF46689 10 64 3.19E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS12740 856e068c9b2ad6b0eb35496063717bf5 171 Gene3D G3DSA:1.10.357.10 55 171 3.0E-10 T 29-03-2018 SMALA_RS28880 1d2077118309cf9a72a6b428f352e649 240 Gene3D G3DSA:1.10.10.10 1 58 1.1E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS28880 1d2077118309cf9a72a6b428f352e649 240 Pfam PF01614 Bacterial transcriptional regulator 115 234 9.0E-26 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal SMALA_RS28880 1d2077118309cf9a72a6b428f352e649 240 SUPERFAMILY SSF46785 2 70 5.46E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS28880 1d2077118309cf9a72a6b428f352e649 240 Gene3D G3DSA:3.30.450.40 63 240 1.9E-49 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS28880 1d2077118309cf9a72a6b428f352e649 240 Pfam PF09339 IclR helix-turn-helix domain 2 51 4.7E-16 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMALA_RS28880 1d2077118309cf9a72a6b428f352e649 240 SMART SM00346 2 87 7.9E-20 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMALA_RS28880 1d2077118309cf9a72a6b428f352e649 240 SUPERFAMILY SSF55781 62 236 1.37E-47 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS19560 422740e0b25ac3c9f3c494669159ef64 485 SUPERFAMILY SSF52540 223 474 2.02E-51 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS19560 422740e0b25ac3c9f3c494669159ef64 485 Pfam PF00772 DnaB-like helicase N terminal domain 50 151 1.1E-36 T 29-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 SMALA_RS19560 422740e0b25ac3c9f3c494669159ef64 485 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 50 483 1.3E-167 T 29-03-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 SMALA_RS19560 422740e0b25ac3c9f3c494669159ef64 485 Gene3D G3DSA:1.10.860.10 43 191 7.9E-55 T 29-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal SMALA_RS19560 422740e0b25ac3c9f3c494669159ef64 485 Pfam PF03796 DnaB-like helicase C terminal domain 225 480 8.6E-108 T 29-03-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 SMALA_RS19560 422740e0b25ac3c9f3c494669159ef64 485 Gene3D G3DSA:3.40.50.300 207 485 1.6E-69 T 29-03-2018 SMALA_RS19560 422740e0b25ac3c9f3c494669159ef64 485 SMART SM00382 242 441 0.0017 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS19560 422740e0b25ac3c9f3c494669159ef64 485 SUPERFAMILY SSF48024 48 159 5.49E-39 T 29-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 SMALA_RS35240 d349d4eece6f3dcbc2f293d8fb889d40 300 SUPERFAMILY SSF52402 162 298 2.26E-18 T 29-03-2018 SMALA_RS35240 d349d4eece6f3dcbc2f293d8fb889d40 300 PRINTS PR01438 Universal stress protein signature 10 28 4.2E-13 T 29-03-2018 IPR006015 Universal stress protein A SMALA_RS35240 d349d4eece6f3dcbc2f293d8fb889d40 300 PRINTS PR01438 Universal stress protein signature 126 148 4.2E-13 T 29-03-2018 IPR006015 Universal stress protein A SMALA_RS35240 d349d4eece6f3dcbc2f293d8fb889d40 300 PRINTS PR01438 Universal stress protein signature 108 120 4.2E-13 T 29-03-2018 IPR006015 Universal stress protein A SMALA_RS35240 d349d4eece6f3dcbc2f293d8fb889d40 300 Pfam PF00582 Universal stress protein family 162 298 3.5E-20 T 29-03-2018 IPR006016 UspA GO:0006950 SMALA_RS35240 d349d4eece6f3dcbc2f293d8fb889d40 300 Pfam PF00582 Universal stress protein family 12 148 1.7E-22 T 29-03-2018 IPR006016 UspA GO:0006950 SMALA_RS35240 d349d4eece6f3dcbc2f293d8fb889d40 300 SUPERFAMILY SSF52402 12 151 1.42E-27 T 29-03-2018 SMALA_RS35240 d349d4eece6f3dcbc2f293d8fb889d40 300 Gene3D G3DSA:3.40.50.620 158 300 4.1E-22 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS35240 d349d4eece6f3dcbc2f293d8fb889d40 300 Gene3D G3DSA:3.40.50.620 2 148 2.5E-30 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS18510 77665802f94a55da06493e5d64722808 524 Gene3D G3DSA:3.40.50.150 161 335 2.2E-25 T 29-03-2018 SMALA_RS18510 77665802f94a55da06493e5d64722808 524 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 242 248 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 SMALA_RS18510 77665802f94a55da06493e5d64722808 524 SUPERFAMILY SSF53335 171 310 9.48E-26 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS18510 77665802f94a55da06493e5d64722808 524 Pfam PF05175 Methyltransferase small domain 173 295 6.0E-12 T 29-03-2018 IPR007848 Methyltransferase small domain GO:0008168 SMALA_RS21365 7ac0d8050137e615859e1ed16d506061 366 Pfam PF00877 NlpC/P60 family 264 348 1.6E-19 T 29-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain SMALA_RS21365 7ac0d8050137e615859e1ed16d506061 366 Gene3D G3DSA:3.90.1720.10 242 354 7.4E-30 T 29-03-2018 SMALA_RS21365 7ac0d8050137e615859e1ed16d506061 366 SUPERFAMILY SSF54001 251 358 1.62E-32 T 29-03-2018 SMALA_RS15845 cb3dc858745c0bc0d9b290ef5576f0b3 452 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 264 369 9.2E-26 T 29-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMALA_RS15845 cb3dc858745c0bc0d9b290ef5576f0b3 452 Gene3D G3DSA:3.40.120.10 160 272 4.0E-36 T 29-03-2018 SMALA_RS15845 cb3dc858745c0bc0d9b290ef5576f0b3 452 SUPERFAMILY SSF53738 6 167 7.06E-31 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMALA_RS15845 cb3dc858745c0bc0d9b290ef5576f0b3 452 Gene3D G3DSA:3.40.120.10 2 159 1.4E-30 T 29-03-2018 SMALA_RS15845 cb3dc858745c0bc0d9b290ef5576f0b3 452 SUPERFAMILY SSF53738 261 365 3.92E-30 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMALA_RS15845 cb3dc858745c0bc0d9b290ef5576f0b3 452 SUPERFAMILY SSF55957 369 452 8.11E-21 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMALA_RS15845 cb3dc858745c0bc0d9b290ef5576f0b3 452 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 156 255 2.3E-25 T 29-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMALA_RS15845 cb3dc858745c0bc0d9b290ef5576f0b3 452 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 235 250 8.5E-22 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMALA_RS15845 cb3dc858745c0bc0d9b290ef5576f0b3 452 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 91 105 8.5E-22 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMALA_RS15845 cb3dc858745c0bc0d9b290ef5576f0b3 452 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 172 191 8.5E-22 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMALA_RS15845 cb3dc858745c0bc0d9b290ef5576f0b3 452 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 206 219 8.5E-22 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMALA_RS15845 cb3dc858745c0bc0d9b290ef5576f0b3 452 Gene3D G3DSA:3.30.310.50 366 452 2.4E-20 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMALA_RS15845 cb3dc858745c0bc0d9b290ef5576f0b3 452 SUPERFAMILY SSF53738 155 257 6.28E-30 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMALA_RS15845 cb3dc858745c0bc0d9b290ef5576f0b3 452 Gene3D G3DSA:3.40.120.10 273 365 1.6E-26 T 29-03-2018 SMALA_RS15845 cb3dc858745c0bc0d9b290ef5576f0b3 452 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 6 132 1.7E-29 T 29-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMALA_RS15845 cb3dc858745c0bc0d9b290ef5576f0b3 452 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 374 450 2.4E-13 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMALA_RS42040 90bde9042b5a83d151336a18a5d130d3 416 Gene3D G3DSA:3.40.605.10 237 416 2.6E-32 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS42040 90bde9042b5a83d151336a18a5d130d3 416 Gene3D G3DSA:3.40.605.10 1 236 5.8E-41 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS42040 90bde9042b5a83d151336a18a5d130d3 416 SUPERFAMILY SSF53720 3 414 9.69E-111 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMALA_RS42040 90bde9042b5a83d151336a18a5d130d3 416 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 2 414 39.028 T 29-03-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 SMALA_RS42040 90bde9042b5a83d151336a18a5d130d3 416 Pfam PF00171 Aldehyde dehydrogenase family 3 282 9.1E-19 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS42040 90bde9042b5a83d151336a18a5d130d3 416 PIRSF PIRSF000151 1 415 3.4E-160 T 29-03-2018 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 SMALA_RS42040 90bde9042b5a83d151336a18a5d130d3 416 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 10 404 1.7E-142 T 29-03-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 SMALA_RS41385 02954c53e92847a01362ea9c020824c9 507 SUPERFAMILY SSF51905 279 368 9.18E-51 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS41385 02954c53e92847a01362ea9c020824c9 507 SUPERFAMILY SSF51905 1 192 9.18E-51 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS41385 02954c53e92847a01362ea9c020824c9 507 Pfam PF01494 FAD binding domain 2 358 2.4E-60 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 SMALA_RS41385 02954c53e92847a01362ea9c020824c9 507 Gene3D G3DSA:3.50.50.60 1 402 1.0E-53 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS41385 02954c53e92847a01362ea9c020824c9 507 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 307 323 1.9E-42 T 29-03-2018 SMALA_RS41385 02954c53e92847a01362ea9c020824c9 507 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 1.9E-42 T 29-03-2018 SMALA_RS41385 02954c53e92847a01362ea9c020824c9 507 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 292 307 1.9E-42 T 29-03-2018 SMALA_RS41385 02954c53e92847a01362ea9c020824c9 507 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 325 343 1.9E-42 T 29-03-2018 SMALA_RS41385 02954c53e92847a01362ea9c020824c9 507 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 343 359 1.9E-42 T 29-03-2018 SMALA_RS41385 02954c53e92847a01362ea9c020824c9 507 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 171 186 1.9E-42 T 29-03-2018 SMALA_RS11725 507898db191f4e798150d6c0d0393884 195 SUPERFAMILY SSF47413 67 134 5.93E-12 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS11725 507898db191f4e798150d6c0d0393884 195 Pfam PF13560 Helix-turn-helix domain 73 130 6.2E-10 T 29-03-2018 SMALA_RS11725 507898db191f4e798150d6c0d0393884 195 Gene3D G3DSA:1.10.260.40 69 132 1.2E-12 T 29-03-2018 SMALA_RS11725 507898db191f4e798150d6c0d0393884 195 SMART SM00530 75 130 5.5E-10 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS27170 e67f756815421bad3794e582ff3d264f 701 Gene3D G3DSA:3.40.1390.20 206 343 9.6E-26 T 29-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like SMALA_RS27170 e67f756815421bad3794e582ff3d264f 701 Pfam PF07085 DRTGG domain 209 319 7.0E-22 T 29-03-2018 IPR010766 DRTGG KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 SMALA_RS27170 e67f756815421bad3794e582ff3d264f 701 SUPERFAMILY SSF52540 4 216 4.78E-12 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS27170 e67f756815421bad3794e582ff3d264f 701 SUPERFAMILY SSF53659 365 686 3.0E-95 T 29-03-2018 SMALA_RS27170 e67f756815421bad3794e582ff3d264f 701 SUPERFAMILY SSF75138 204 322 5.89E-19 T 29-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like SMALA_RS27170 e67f756815421bad3794e582ff3d264f 701 TIGRFAM TIGR00651 pta: phosphate acetyltransferase 382 683 5.2E-123 T 29-03-2018 IPR004614 Phosphate acetyltransferase GO:0016407 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 SMALA_RS27170 e67f756815421bad3794e582ff3d264f 701 Pfam PF13500 AAA domain 3 205 7.6E-18 T 29-03-2018 SMALA_RS27170 e67f756815421bad3794e582ff3d264f 701 PIRSF PIRSF006107 1 691 3.0E-178 T 29-03-2018 IPR016475 Phosphate acetyltransferase, bacteria GO:0008959 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 SMALA_RS27170 e67f756815421bad3794e582ff3d264f 701 Gene3D G3DSA:3.40.50.300 1 205 1.1E-27 T 29-03-2018 SMALA_RS27170 e67f756815421bad3794e582ff3d264f 701 Gene3D G3DSA:3.40.718.10 383 671 1.0E-66 T 29-03-2018 SMALA_RS27170 e67f756815421bad3794e582ff3d264f 701 Pfam PF01515 Phosphate acetyl/butaryl transferase 366 683 5.7E-127 T 29-03-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 SMALA_RS10085 cf475583440cf48e7265e59cfa56aaa9 246 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 6 221 3.4E-30 T 29-03-2018 IPR003111 Lon, substrate-binding domain SMALA_RS10085 cf475583440cf48e7265e59cfa56aaa9 246 Gene3D G3DSA:2.30.130.40 2 139 2.2E-34 T 29-03-2018 SMALA_RS10085 cf475583440cf48e7265e59cfa56aaa9 246 SUPERFAMILY SSF88697 5 221 6.96E-36 T 29-03-2018 IPR015947 PUA-like domain SMALA_RS10085 cf475583440cf48e7265e59cfa56aaa9 246 Gene3D G3DSA:1.10.4060.10 141 228 6.6E-10 T 29-03-2018 SMALA_RS10085 cf475583440cf48e7265e59cfa56aaa9 246 SMART SM00464 5 222 4.2E-40 T 29-03-2018 IPR003111 Lon, substrate-binding domain SMALA_RS29250 db04d8932d8f103f474e4ecf4de61315 225 SUPERFAMILY SSF51735 2 145 5.91E-28 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS29250 db04d8932d8f103f474e4ecf4de61315 225 Pfam PF02080 TrkA-C domain 149 216 4.4E-12 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 SMALA_RS29250 db04d8932d8f103f474e4ecf4de61315 225 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 4.0E-7 T 29-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 SMALA_RS29250 db04d8932d8f103f474e4ecf4de61315 225 PRINTS PR00335 TrkA potassium uptake protein signature 59 69 4.0E-7 T 29-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 SMALA_RS29250 db04d8932d8f103f474e4ecf4de61315 225 PRINTS PR00335 TrkA potassium uptake protein signature 72 86 4.0E-7 T 29-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 SMALA_RS29250 db04d8932d8f103f474e4ecf4de61315 225 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 4.0E-7 T 29-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 SMALA_RS29250 db04d8932d8f103f474e4ecf4de61315 225 Gene3D G3DSA:3.40.50.720 2 145 2.8E-24 T 29-03-2018 SMALA_RS29250 db04d8932d8f103f474e4ecf4de61315 225 Gene3D G3DSA:3.30.70.1450 146 222 7.5E-18 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 SMALA_RS29250 db04d8932d8f103f474e4ecf4de61315 225 Pfam PF02254 TrkA-N domain 3 118 9.9E-25 T 29-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 SMALA_RS29250 db04d8932d8f103f474e4ecf4de61315 225 SUPERFAMILY SSF116726 133 216 5.36E-14 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 SMALA_RS37295 67b55b9b6daaae6fe9db9e753bf34639 466 SUPERFAMILY SSF55424 343 465 1.15E-36 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SMALA_RS37295 67b55b9b6daaae6fe9db9e753bf34639 466 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 347 455 3.5E-32 T 29-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 SMALA_RS37295 67b55b9b6daaae6fe9db9e753bf34639 466 PIRSF PIRSF000350 1 464 1.8E-75 T 29-03-2018 SMALA_RS37295 67b55b9b6daaae6fe9db9e753bf34639 466 Gene3D G3DSA:3.40.50.720 160 334 7.2E-35 T 29-03-2018 SMALA_RS37295 67b55b9b6daaae6fe9db9e753bf34639 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 408 423 2.5E-60 T 29-03-2018 SMALA_RS37295 67b55b9b6daaae6fe9db9e753bf34639 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 430 450 2.5E-60 T 29-03-2018 SMALA_RS37295 67b55b9b6daaae6fe9db9e753bf34639 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 343 364 2.5E-60 T 29-03-2018 SMALA_RS37295 67b55b9b6daaae6fe9db9e753bf34639 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 141 150 2.5E-60 T 29-03-2018 SMALA_RS37295 67b55b9b6daaae6fe9db9e753bf34639 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 176 201 2.5E-60 T 29-03-2018 SMALA_RS37295 67b55b9b6daaae6fe9db9e753bf34639 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 264 278 2.5E-60 T 29-03-2018 SMALA_RS37295 67b55b9b6daaae6fe9db9e753bf34639 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 2.5E-60 T 29-03-2018 SMALA_RS37295 67b55b9b6daaae6fe9db9e753bf34639 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 2.5E-60 T 29-03-2018 SMALA_RS37295 67b55b9b6daaae6fe9db9e753bf34639 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 307 314 2.5E-60 T 29-03-2018 SMALA_RS37295 67b55b9b6daaae6fe9db9e753bf34639 466 Gene3D G3DSA:3.50.50.60 1 159 2.9E-27 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS37295 67b55b9b6daaae6fe9db9e753bf34639 466 Gene3D G3DSA:3.30.390.30 335 462 2.5E-37 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SMALA_RS37295 67b55b9b6daaae6fe9db9e753bf34639 466 SUPERFAMILY SSF51905 2 336 7.25E-59 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS37295 67b55b9b6daaae6fe9db9e753bf34639 466 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 327 8.7E-64 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS37295 67b55b9b6daaae6fe9db9e753bf34639 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 292 314 4.6E-33 T 29-03-2018 SMALA_RS37295 67b55b9b6daaae6fe9db9e753bf34639 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 263 279 4.6E-33 T 29-03-2018 SMALA_RS37295 67b55b9b6daaae6fe9db9e753bf34639 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 176 194 4.6E-33 T 29-03-2018 SMALA_RS37295 67b55b9b6daaae6fe9db9e753bf34639 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 4.6E-33 T 29-03-2018 SMALA_RS37295 67b55b9b6daaae6fe9db9e753bf34639 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 138 156 4.6E-33 T 29-03-2018 SMALA_RS37295 67b55b9b6daaae6fe9db9e753bf34639 466 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 4 465 7.6E-162 T 29-03-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 SMALA_RS37295 67b55b9b6daaae6fe9db9e753bf34639 466 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 39 49 - T 29-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 SMALA_RS34720 ae2a47625df851d10bd9779ba5cfdfd2 227 SUPERFAMILY SSF53335 45 221 4.34E-31 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS34720 ae2a47625df851d10bd9779ba5cfdfd2 227 Pfam PF08241 Methyltransferase domain 52 144 2.0E-16 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 SMALA_RS34720 ae2a47625df851d10bd9779ba5cfdfd2 227 Gene3D G3DSA:3.40.50.150 4 222 2.0E-21 T 29-03-2018 SMALA_RS35375 82bfc7b5f7df3e51560db1b057579856 867 Pfam PF07691 PA14 domain 85 181 5.5E-28 T 29-03-2018 IPR011658 PA14 domain SMALA_RS35375 82bfc7b5f7df3e51560db1b057579856 867 Pfam PF00703 Glycosyl hydrolases family 2 522 579 2.4E-9 T 29-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 SMALA_RS35375 82bfc7b5f7df3e51560db1b057579856 867 SUPERFAMILY SSF49303 489 580 5.76E-12 T 29-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 SMALA_RS35375 82bfc7b5f7df3e51560db1b057579856 867 Gene3D G3DSA:3.90.182.10 31 283 3.4E-42 T 29-03-2018 SMALA_RS35375 82bfc7b5f7df3e51560db1b057579856 867 SUPERFAMILY SSF49785 313 485 3.04E-46 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS35375 82bfc7b5f7df3e51560db1b057579856 867 SUPERFAMILY SSF51445 576 850 2.97E-63 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS35375 82bfc7b5f7df3e51560db1b057579856 867 SUPERFAMILY SSF56988 43 255 1.96E-48 T 29-03-2018 SMALA_RS35375 82bfc7b5f7df3e51560db1b057579856 867 Gene3D G3DSA:2.60.40.10 487 571 3.6E-16 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS35375 82bfc7b5f7df3e51560db1b057579856 867 SMART SM00758 42 184 5.7E-43 T 29-03-2018 IPR011658 PA14 domain SMALA_RS35375 82bfc7b5f7df3e51560db1b057579856 867 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 619 732 2.7E-6 T 29-03-2018 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 SMALA_RS35375 82bfc7b5f7df3e51560db1b057579856 867 Gene3D G3DSA:2.60.120.260 287 486 6.8E-44 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS35375 82bfc7b5f7df3e51560db1b057579856 867 Gene3D G3DSA:3.20.20.80 572 805 1.2E-36 T 29-03-2018 SMALA_RS35375 82bfc7b5f7df3e51560db1b057579856 867 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 356 452 3.6E-14 T 29-03-2018 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 SMALA_RS19315 8d65b584701ba0c2a18c6d6842ef0fdf 311 PIRSF PIRSF001500 2 279 2.1E-59 T 29-03-2018 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 SMALA_RS19315 8d65b584701ba0c2a18c6d6842ef0fdf 311 Gene3D G3DSA:3.40.190.10 2 97 1.1E-27 T 29-03-2018 SMALA_RS19315 8d65b584701ba0c2a18c6d6842ef0fdf 311 Pfam PF01842 ACT domain 198 254 1.1E-7 T 29-03-2018 IPR002912 ACT domain SMALA_RS19315 8d65b584701ba0c2a18c6d6842ef0fdf 311 SUPERFAMILY SSF53850 5 188 2.68E-48 T 29-03-2018 SMALA_RS19315 8d65b584701ba0c2a18c6d6842ef0fdf 311 Gene3D G3DSA:3.30.70.260 187 281 6.5E-30 T 29-03-2018 SMALA_RS19315 8d65b584701ba0c2a18c6d6842ef0fdf 311 SUPERFAMILY SSF55021 185 276 6.66E-24 T 29-03-2018 SMALA_RS19315 8d65b584701ba0c2a18c6d6842ef0fdf 311 Pfam PF00800 Prephenate dehydratase 7 183 8.2E-46 T 29-03-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 SMALA_RS19315 8d65b584701ba0c2a18c6d6842ef0fdf 311 Gene3D G3DSA:3.40.190.10 98 166 2.4E-21 T 29-03-2018 SMALA_RS22900 55b59ead6950f53516c78741aa0dd5b4 482 SUPERFAMILY SSF52777 40 178 1.02E-10 T 29-03-2018 SMALA_RS22900 55b59ead6950f53516c78741aa0dd5b4 482 Gene3D G3DSA:3.30.559.10 238 455 1.1E-38 T 29-03-2018 SMALA_RS22900 55b59ead6950f53516c78741aa0dd5b4 482 Pfam PF02458 Transferase family 242 453 3.7E-21 T 29-03-2018 IPR003480 Transferase GO:0016747 SMALA_RS22900 55b59ead6950f53516c78741aa0dd5b4 482 Pfam PF02458 Transferase family 23 178 1.6E-32 T 29-03-2018 IPR003480 Transferase GO:0016747 SMALA_RS22900 55b59ead6950f53516c78741aa0dd5b4 482 Gene3D G3DSA:3.30.559.10 10 200 5.0E-31 T 29-03-2018 SMALA_RS31940 c7da630ffc9c3e3fe4119ab6736a5549 380 Pfam PF02515 CoA-transferase family III 12 355 6.9E-87 T 29-03-2018 IPR003673 CoA-transferase family III GO:0003824 SMALA_RS31940 c7da630ffc9c3e3fe4119ab6736a5549 380 SUPERFAMILY SSF89796 10 372 1.29E-116 T 29-03-2018 IPR023606 CoA-transferase family III domain SMALA_RS31940 c7da630ffc9c3e3fe4119ab6736a5549 380 Gene3D G3DSA:3.40.50.10540 6 374 1.2E-116 T 29-03-2018 IPR023606 CoA-transferase family III domain SMALA_RS02950 ce4e6faaf1b36ddd1b71f9dfce66d517 279 Gene3D G3DSA:3.60.15.10 1 275 2.8E-32 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS02950 ce4e6faaf1b36ddd1b71f9dfce66d517 279 SUPERFAMILY SSF56281 11 251 2.94E-24 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS02950 ce4e6faaf1b36ddd1b71f9dfce66d517 279 Pfam PF12706 Beta-lactamase superfamily domain 29 233 8.2E-14 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS42290 e904d62ad4d2263b7bcc4e555f3da875 353 Gene3D G3DSA:2.60.120.620 1 279 6.0E-42 T 29-03-2018 SMALA_RS42290 e904d62ad4d2263b7bcc4e555f3da875 353 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 11 256 1.4E-21 T 29-03-2018 IPR008775 Phytanoyl-CoA dioxygenase SMALA_RS42290 e904d62ad4d2263b7bcc4e555f3da875 353 SUPERFAMILY SSF51197 1 47 2.47E-44 T 29-03-2018 SMALA_RS42290 e904d62ad4d2263b7bcc4e555f3da875 353 SUPERFAMILY SSF51197 85 280 2.47E-44 T 29-03-2018 SMALA_RS35795 1824ced479be18e89924a90f4d2b0f42 111 SUPERFAMILY SSF46785 3 106 9.28E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS35795 1824ced479be18e89924a90f4d2b0f42 111 Pfam PF01638 HxlR-like helix-turn-helix 16 102 2.0E-31 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type SMALA_RS35795 1824ced479be18e89924a90f4d2b0f42 111 Gene3D G3DSA:1.10.10.10 14 110 3.3E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS31060 3e62b63dce84ddae9511c58323200f20 356 Gene3D G3DSA:3.40.50.150 102 348 3.2E-35 T 29-03-2018 SMALA_RS31060 3e62b63dce84ddae9511c58323200f20 356 Pfam PF00891 O-methyltransferase 121 334 2.2E-33 T 29-03-2018 IPR001077 O-methyltransferase, family 2 GO:0008171 SMALA_RS31060 3e62b63dce84ddae9511c58323200f20 356 SUPERFAMILY SSF46785 18 105 2.08E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS31060 3e62b63dce84ddae9511c58323200f20 356 SUPERFAMILY SSF53335 106 341 4.92E-41 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS31060 3e62b63dce84ddae9511c58323200f20 356 Gene3D G3DSA:1.10.10.10 16 101 4.2E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS31060 3e62b63dce84ddae9511c58323200f20 356 PIRSF PIRSF005739 19 346 2.1E-42 T 29-03-2018 IPR016461 O-methyltransferase COMT-type GO:0008168 SMALA_RS04970 b8cf2de6417b22c5ff68d68973153db3 624 Gene3D G3DSA:3.30.200.20 4 94 5.9E-15 T 29-03-2018 SMALA_RS04970 b8cf2de6417b22c5ff68d68973153db3 624 Pfam PF00069 Protein kinase domain 18 216 4.4E-36 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMALA_RS04970 b8cf2de6417b22c5ff68d68973153db3 624 Gene3D G3DSA:1.10.510.10 95 276 5.5E-39 T 29-03-2018 SMALA_RS04970 b8cf2de6417b22c5ff68d68973153db3 624 SUPERFAMILY SSF56112 18 274 5.8E-54 T 29-03-2018 IPR011009 Protein kinase-like domain SMALA_RS04970 b8cf2de6417b22c5ff68d68973153db3 624 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 128 140 - T 29-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMALA_RS04970 b8cf2de6417b22c5ff68d68973153db3 624 SMART SM00220 10 252 5.5E-32 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMALA_RS40495 2f8cfc86b875dfba406eee0ee1315907 208 Gene3D G3DSA:3.40.1000.10 73 206 3.1E-9 T 29-03-2018 SMALA_RS11275 1836c56f7305b5a83d7243a0ad5e79c9 292 Gene3D G3DSA:3.40.190.10 90 182 1.4E-16 T 29-03-2018 SMALA_RS11275 1836c56f7305b5a83d7243a0ad5e79c9 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.6E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS11275 1836c56f7305b5a83d7243a0ad5e79c9 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.6E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS11275 1836c56f7305b5a83d7243a0ad5e79c9 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.6E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS11275 1836c56f7305b5a83d7243a0ad5e79c9 292 Pfam PF03466 LysR substrate binding domain 88 290 9.6E-34 T 29-03-2018 IPR005119 LysR, substrate-binding SMALA_RS11275 1836c56f7305b5a83d7243a0ad5e79c9 292 Gene3D G3DSA:3.40.190.10 183 265 5.1E-13 T 29-03-2018 SMALA_RS11275 1836c56f7305b5a83d7243a0ad5e79c9 292 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 9.9E-23 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS11275 1836c56f7305b5a83d7243a0ad5e79c9 292 SUPERFAMILY SSF46785 2 85 6.16E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS11275 1836c56f7305b5a83d7243a0ad5e79c9 292 Gene3D G3DSA:1.10.10.10 1 83 3.1E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS11275 1836c56f7305b5a83d7243a0ad5e79c9 292 SUPERFAMILY SSF53850 91 291 1.11E-27 T 29-03-2018 SMALA_RS17970 183b099d4d07b8a3aae580b26bc114cc 173 Pfam PF00583 Acetyltransferase (GNAT) family 48 126 2.3E-10 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SMALA_RS17970 183b099d4d07b8a3aae580b26bc114cc 173 SUPERFAMILY SSF55729 10 135 1.08E-20 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS17970 183b099d4d07b8a3aae580b26bc114cc 173 Gene3D G3DSA:3.40.630.30 9 152 1.1E-21 T 29-03-2018 SMALA_RS21655 1f5312457a874261034df6b2b1bdf336 308 Gene3D G3DSA:1.10.1670.10 134 240 8.4E-33 T 29-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 SMALA_RS21655 1f5312457a874261034df6b2b1bdf336 308 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 51 179 3.9E-11 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 SMALA_RS21655 1f5312457a874261034df6b2b1bdf336 308 SMART SM00478 55 207 5.0E-35 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 SMALA_RS21655 1f5312457a874261034df6b2b1bdf336 308 ProSitePatterns PS01155 Endonuclease III family signature. 118 147 - T 29-03-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 SMALA_RS21655 1f5312457a874261034df6b2b1bdf336 308 SUPERFAMILY SSF48150 22 235 8.48E-64 T 29-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 SMALA_RS21655 1f5312457a874261034df6b2b1bdf336 308 Pfam PF00633 Helix-hairpin-helix motif 115 144 1.4E-8 T 29-03-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 SMALA_RS21655 1f5312457a874261034df6b2b1bdf336 308 SMART SM00525 208 228 4.9E-4 T 29-03-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 SMALA_RS21655 1f5312457a874261034df6b2b1bdf336 308 Gene3D G3DSA:1.10.340.30 36 133 2.0E-28 T 29-03-2018 SMALA_RS00075 6af3b1b4659ee09d6d7f95f678c4fde8 82 Gene3D G3DSA:1.20.1250.20 1 67 8.4E-4 T 29-03-2018 SMALA_RS00075 6af3b1b4659ee09d6d7f95f678c4fde8 82 Pfam PF14012 Protein of unknown function (DUF4229) 1 67 9.5E-21 T 29-03-2018 IPR025323 Protein of unknown function DUF4229 SMALA_RS22015 6af3b1b4659ee09d6d7f95f678c4fde8 82 Gene3D G3DSA:1.20.1250.20 1 67 8.4E-4 T 29-03-2018 SMALA_RS22015 6af3b1b4659ee09d6d7f95f678c4fde8 82 Pfam PF14012 Protein of unknown function (DUF4229) 1 67 9.5E-21 T 29-03-2018 IPR025323 Protein of unknown function DUF4229 SMALA_RS07710 0dccb53fc496440fb919906893f6b903 383 Pfam PF13560 Helix-turn-helix domain 22 80 1.0E-10 T 29-03-2018 SMALA_RS07710 0dccb53fc496440fb919906893f6b903 383 SUPERFAMILY SSF47413 21 83 2.41E-9 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS07710 0dccb53fc496440fb919906893f6b903 383 Gene3D G3DSA:1.10.260.40 15 97 3.0E-11 T 29-03-2018 SMALA_RS07710 0dccb53fc496440fb919906893f6b903 383 SMART SM00530 25 81 0.005 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS26250 cfc4ec116e80a7069779a1686294f555 501 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 157 172 5.2E-35 T 29-03-2018 SMALA_RS26250 cfc4ec116e80a7069779a1686294f555 501 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 280 295 5.2E-35 T 29-03-2018 SMALA_RS26250 cfc4ec116e80a7069779a1686294f555 501 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 295 311 5.2E-35 T 29-03-2018 SMALA_RS26250 cfc4ec116e80a7069779a1686294f555 501 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 330 346 5.2E-35 T 29-03-2018 SMALA_RS26250 cfc4ec116e80a7069779a1686294f555 501 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 8 30 5.2E-35 T 29-03-2018 SMALA_RS26250 cfc4ec116e80a7069779a1686294f555 501 SUPERFAMILY SSF52833 380 483 7.83E-9 T 29-03-2018 IPR012336 Thioredoxin-like fold SMALA_RS26250 cfc4ec116e80a7069779a1686294f555 501 Gene3D G3DSA:3.50.50.60 3 367 8.7E-56 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS26250 cfc4ec116e80a7069779a1686294f555 501 Gene3D G3DSA:3.40.30.20 409 490 9.6E-9 T 29-03-2018 SMALA_RS26250 cfc4ec116e80a7069779a1686294f555 501 Pfam PF01494 FAD binding domain 8 342 1.8E-75 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 SMALA_RS26250 cfc4ec116e80a7069779a1686294f555 501 SUPERFAMILY SSF51905 7 178 1.78E-60 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS26250 cfc4ec116e80a7069779a1686294f555 501 SUPERFAMILY SSF51905 267 350 1.78E-60 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS21825 31a0e362608b9116f56f9ed570133ff0 489 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 4 462 6.1E-107 T 29-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 SMALA_RS21825 31a0e362608b9116f56f9ed570133ff0 489 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 362 461 3.7E-21 T 29-03-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 SMALA_RS21825 31a0e362608b9116f56f9ed570133ff0 489 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 184 232 1.9E-11 T 29-03-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase SMALA_RS21825 31a0e362608b9116f56f9ed570133ff0 489 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 256 340 2.1E-7 T 29-03-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase SMALA_RS21825 31a0e362608b9116f56f9ed570133ff0 489 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 99 122 - T 29-03-2018 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 SMALA_RS21825 31a0e362608b9116f56f9ed570133ff0 489 Gene3D G3DSA:3.40.50.720 161 348 2.6E-24 T 29-03-2018 SMALA_RS21825 31a0e362608b9116f56f9ed570133ff0 489 SUPERFAMILY SSF69075 360 462 4.97E-17 T 29-03-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 SMALA_RS21825 31a0e362608b9116f56f9ed570133ff0 489 Gene3D G3DSA:1.10.1200.70 374 462 4.8E-22 T 29-03-2018 SMALA_RS21825 31a0e362608b9116f56f9ed570133ff0 489 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 6 156 1.3E-43 T 29-03-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 SMALA_RS21825 31a0e362608b9116f56f9ed570133ff0 489 SUPERFAMILY SSF51735 182 338 3.84E-18 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS21825 31a0e362608b9116f56f9ed570133ff0 489 SUPERFAMILY SSF69742 1 158 1.31E-43 T 29-03-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 SMALA_RS21825 31a0e362608b9116f56f9ed570133ff0 489 PIRSF PIRSF000445 1 473 3.8E-128 T 29-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 SMALA_RS21825 31a0e362608b9116f56f9ed570133ff0 489 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 2 459 25.368 T 29-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 SMALA_RS33820 eb105d30e6c05fafd50c6aedf16e8224 509 PIRSF PIRSF000538 368 491 9.9E-9 T 29-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 SMALA_RS33820 eb105d30e6c05fafd50c6aedf16e8224 509 PIRSF PIRSF000538 9 302 5.4E-30 T 29-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 SMALA_RS33820 eb105d30e6c05fafd50c6aedf16e8224 509 Gene3D G3DSA:3.30.420.40 3 246 1.2E-48 T 29-03-2018 SMALA_RS33820 eb105d30e6c05fafd50c6aedf16e8224 509 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 258 448 5.7E-31 T 29-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 SMALA_RS33820 eb105d30e6c05fafd50c6aedf16e8224 509 SUPERFAMILY SSF53067 255 486 2.46E-34 T 29-03-2018 SMALA_RS33820 eb105d30e6c05fafd50c6aedf16e8224 509 SUPERFAMILY SSF53067 8 246 7.77E-47 T 29-03-2018 SMALA_RS33820 eb105d30e6c05fafd50c6aedf16e8224 509 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 10 249 2.6E-29 T 29-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 SMALA_RS33820 eb105d30e6c05fafd50c6aedf16e8224 509 Gene3D G3DSA:3.30.420.40 247 496 2.5E-47 T 29-03-2018 SMALA_RS35745 576c1cd8d20f1d280886cb0b11bcf4ce 368 SMART SM00729 8 208 8.6E-4 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 SMALA_RS35745 576c1cd8d20f1d280886cb0b11bcf4ce 368 Gene3D G3DSA:3.20.20.70 3 303 3.8E-42 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS35745 576c1cd8d20f1d280886cb0b11bcf4ce 368 Hamap MF_00660 Coenzyme PQQ synthesis protein E [pqqE]. 1 368 155.714 T 29-03-2018 IPR011843 Coenzyme PQQ biosynthesis protein E, bacteria GO:0018189|GO:0051539 SMALA_RS35745 576c1cd8d20f1d280886cb0b11bcf4ce 368 PIRSF PIRSF037420 1 350 2.7E-96 T 29-03-2018 SMALA_RS35745 576c1cd8d20f1d280886cb0b11bcf4ce 368 Pfam PF13186 Iron-sulfur cluster-binding domain 237 302 4.1E-6 T 29-03-2018 IPR023885 4Fe4S-binding SPASM domain SMALA_RS35745 576c1cd8d20f1d280886cb0b11bcf4ce 368 Pfam PF13353 4Fe-4S single cluster domain 15 91 1.3E-5 T 29-03-2018 SMALA_RS35745 576c1cd8d20f1d280886cb0b11bcf4ce 368 SUPERFAMILY SSF102114 7 312 1.83E-63 T 29-03-2018 SMALA_RS35745 576c1cd8d20f1d280886cb0b11bcf4ce 368 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 244 330 1.2E-7 T 29-03-2018 IPR023885 4Fe4S-binding SPASM domain SMALA_RS35745 576c1cd8d20f1d280886cb0b11bcf4ce 368 TIGRFAM TIGR02109 PQQ_syn_pqqE: coenzyme PQQ biosynthesis enzyme PqqE 5 342 4.1E-151 T 29-03-2018 IPR011843 Coenzyme PQQ biosynthesis protein E, bacteria GO:0018189|GO:0051539 SMALA_RS35745 576c1cd8d20f1d280886cb0b11bcf4ce 368 Pfam PF04055 Radical SAM superfamily 14 166 3.5E-21 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 SMALA_RS12095 5f271426a9b26c3bede824820837cefa 329 Gene3D G3DSA:3.20.20.70 50 283 7.4E-4 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS35705 7eb3c256c69ad945607d87239e00908a 452 SUPERFAMILY SSF54368 18 117 9.02E-6 T 29-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SMALA_RS35705 7eb3c256c69ad945607d87239e00908a 452 SMART SM01230 119 369 1.4E-62 T 29-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SMALA_RS35705 7eb3c256c69ad945607d87239e00908a 452 Gene3D G3DSA:3.10.20.70 19 115 7.6E-18 T 29-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SMALA_RS35705 7eb3c256c69ad945607d87239e00908a 452 SUPERFAMILY SSF55931 119 438 1.5E-76 T 29-03-2018 SMALA_RS35705 7eb3c256c69ad945607d87239e00908a 452 Gene3D G3DSA:3.30.590.10 116 448 9.7E-87 T 29-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 SMALA_RS35705 7eb3c256c69ad945607d87239e00908a 452 Pfam PF00120 Glutamine synthetase, catalytic domain 121 438 8.6E-71 T 29-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SMALA_RS02405 ce0b949dd2720b95353b78c08d061ade 242 TIGRFAM TIGR02046 sdhC_b558_fam: succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family 27 241 3.0E-78 T 29-03-2018 IPR011138 Succinate dehydrogenase cytochrome b558 subunit SMALA_RS02405 ce0b949dd2720b95353b78c08d061ade 242 Gene3D G3DSA:1.20.1300.10 6 242 3.0E-55 T 29-03-2018 SMALA_RS02405 ce0b949dd2720b95353b78c08d061ade 242 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 121 227 6.9E-6 T 29-03-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMALA_RS02405 ce0b949dd2720b95353b78c08d061ade 242 SUPERFAMILY SSF81343 13 241 1.47E-53 T 29-03-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMALA_RS34410 d72ca615cead5fb7899399c2914349e4 180 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 94 127 9.1E-6 T 29-03-2018 IPR001451 Hexapeptide repeat SMALA_RS34410 d72ca615cead5fb7899399c2914349e4 180 Gene3D G3DSA:2.160.10.10 7 179 9.8E-43 T 29-03-2018 SMALA_RS34410 d72ca615cead5fb7899399c2914349e4 180 SUPERFAMILY SSF51161 12 175 5.41E-48 T 29-03-2018 IPR011004 Trimeric LpxA-like SMALA_RS43040 5ddd6aa9a40f129f505013207b121c4d 262 SUPERFAMILY SSF52540 103 234 1.72E-23 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS43040 5ddd6aa9a40f129f505013207b121c4d 262 PIRSF PIRSF003073 8 262 7.1E-78 T 29-03-2018 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein SMALA_RS43040 5ddd6aa9a40f129f505013207b121c4d 262 SMART SM00382 108 255 2.7E-4 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS43040 5ddd6aa9a40f129f505013207b121c4d 262 Pfam PF01695 IstB-like ATP binding protein 64 238 1.2E-52 T 29-03-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 SMALA_RS43040 5ddd6aa9a40f129f505013207b121c4d 262 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 171 185 9.8E-8 T 29-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like SMALA_RS43040 5ddd6aa9a40f129f505013207b121c4d 262 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 109 129 9.8E-8 T 29-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like SMALA_RS43040 5ddd6aa9a40f129f505013207b121c4d 262 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 139 153 9.8E-8 T 29-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like SMALA_RS43040 5ddd6aa9a40f129f505013207b121c4d 262 Gene3D G3DSA:3.40.50.300 78 240 8.3E-17 T 29-03-2018 SMALA_RS19470 10dd60471a512c51c0024ad50c157466 105 Pfam PF07883 Cupin domain 34 100 2.3E-13 T 29-03-2018 IPR013096 Cupin 2, conserved barrel SMALA_RS19470 10dd60471a512c51c0024ad50c157466 105 Gene3D G3DSA:2.60.120.10 2 105 3.8E-21 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SMALA_RS19470 10dd60471a512c51c0024ad50c157466 105 SUPERFAMILY SSF51182 19 103 1.01E-19 T 29-03-2018 IPR011051 RmlC-like cupin domain SMALA_RS17600 4039b1a6396aee73abec31093375836b 537 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 438 454 9.1E-16 T 29-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 SMALA_RS17600 4039b1a6396aee73abec31093375836b 537 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 350 366 9.1E-16 T 29-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 SMALA_RS17600 4039b1a6396aee73abec31093375836b 537 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 314 334 9.1E-16 T 29-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 SMALA_RS17600 4039b1a6396aee73abec31093375836b 537 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 371 382 9.1E-16 T 29-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 SMALA_RS17600 4039b1a6396aee73abec31093375836b 537 Pfam PF07504 Fungalysin/Thermolysin Propeptide Motif 80 124 4.6E-14 T 29-03-2018 IPR011096 FTP domain SMALA_RS17600 4039b1a6396aee73abec31093375836b 537 Gene3D G3DSA:3.10.170.10 215 363 2.0E-47 T 29-03-2018 SMALA_RS17600 4039b1a6396aee73abec31093375836b 537 SUPERFAMILY SSF55486 214 536 1.26E-84 T 29-03-2018 SMALA_RS17600 4039b1a6396aee73abec31093375836b 537 Gene3D G3DSA:1.10.390.10 364 537 2.5E-49 T 29-03-2018 SMALA_RS17600 4039b1a6396aee73abec31093375836b 537 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 216 358 7.7E-50 T 29-03-2018 IPR013856 Peptidase M4 domain GO:0004222 SMALA_RS17600 4039b1a6396aee73abec31093375836b 537 Gene3D G3DSA:3.40.1410.10 43 191 4.4E-4 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMALA_RS17600 4039b1a6396aee73abec31093375836b 537 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 362 536 8.6E-53 T 29-03-2018 IPR001570 Peptidase M4, C-terminal GO:0004222 SMALA_RS03555 edcac139cd1bf0fc222eaa4cefb7b251 214 Gene3D G3DSA:3.40.630.20 1 214 1.6E-59 T 29-03-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like SMALA_RS03555 edcac139cd1bf0fc222eaa4cefb7b251 214 Hamap MF_00417 Pyrrolidone-carboxylate peptidase [pcp]. 2 200 37.026 T 29-03-2018 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 SMALA_RS03555 edcac139cd1bf0fc222eaa4cefb7b251 214 PIRSF PIRSF015592 1 212 3.3E-77 T 29-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 SMALA_RS03555 edcac139cd1bf0fc222eaa4cefb7b251 214 TIGRFAM TIGR00504 pyro_pdase: pyroglutamyl-peptidase I 3 211 2.7E-76 T 29-03-2018 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 SMALA_RS03555 edcac139cd1bf0fc222eaa4cefb7b251 214 SUPERFAMILY SSF53182 3 213 3.79E-66 T 29-03-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like SMALA_RS03555 edcac139cd1bf0fc222eaa4cefb7b251 214 Pfam PF01470 Pyroglutamyl peptidase 3 200 1.0E-70 T 29-03-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like SMALA_RS03555 edcac139cd1bf0fc222eaa4cefb7b251 214 ProSitePatterns PS01334 Pyrrolidone-carboxylate peptidase cysteine active site. 130 144 - T 29-03-2018 IPR033694 Pyroglutamyl peptidase I, Cys active site SMALA_RS03555 edcac139cd1bf0fc222eaa4cefb7b251 214 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 4 27 3.4E-46 T 29-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 SMALA_RS03555 edcac139cd1bf0fc222eaa4cefb7b251 214 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 62 74 3.4E-46 T 29-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 SMALA_RS03555 edcac139cd1bf0fc222eaa4cefb7b251 214 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 80 100 3.4E-46 T 29-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 SMALA_RS03555 edcac139cd1bf0fc222eaa4cefb7b251 214 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 132 148 3.4E-46 T 29-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 SMALA_RS03555 edcac139cd1bf0fc222eaa4cefb7b251 214 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 162 174 3.4E-46 T 29-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 SMALA_RS23530 7f2cece1f340415ecca531037853891e 403 SUPERFAMILY SSF51338 365 402 5.56E-16 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS23530 7f2cece1f340415ecca531037853891e 403 SUPERFAMILY SSF51338 2 53 5.56E-16 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS23530 7f2cece1f340415ecca531037853891e 403 Gene3D G3DSA:2.30.40.10 4 68 5.0E-15 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS23530 7f2cece1f340415ecca531037853891e 403 SUPERFAMILY SSF51556 53 362 5.03E-79 T 29-03-2018 IPR032466 Metal-dependent hydrolase SMALA_RS23530 7f2cece1f340415ecca531037853891e 403 Gene3D G3DSA:3.20.20.140 69 362 2.8E-48 T 29-03-2018 SMALA_RS23530 7f2cece1f340415ecca531037853891e 403 Pfam PF01979 Amidohydrolase family 50 402 2.1E-39 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 SMALA_RS20165 186b9a451e15fc54a61ffc3dd3082b18 585 Gene3D G3DSA:1.10.730.10 390 564 4.7E-34 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMALA_RS20165 186b9a451e15fc54a61ffc3dd3082b18 585 Gene3D G3DSA:3.40.50.620 253 389 8.1E-15 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS20165 186b9a451e15fc54a61ffc3dd3082b18 585 Gene3D G3DSA:3.40.50.620 2 73 1.9E-13 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS20165 186b9a451e15fc54a61ffc3dd3082b18 585 SUPERFAMILY SSF57770 139 172 1.07E-11 T 29-03-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 SMALA_RS20165 186b9a451e15fc54a61ffc3dd3082b18 585 Gene3D G3DSA:2.170.220.10 163 252 8.2E-21 T 29-03-2018 SMALA_RS20165 186b9a451e15fc54a61ffc3dd3082b18 585 Pfam PF08264 Anticodon-binding domain of tRNA 441 518 2.0E-6 T 29-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 SMALA_RS20165 186b9a451e15fc54a61ffc3dd3082b18 585 SUPERFAMILY SSF52374 174 401 2.81E-81 T 29-03-2018 SMALA_RS20165 186b9a451e15fc54a61ffc3dd3082b18 585 SUPERFAMILY SSF52374 4 138 2.81E-81 T 29-03-2018 SMALA_RS20165 186b9a451e15fc54a61ffc3dd3082b18 585 Hamap MF_00098 Methionine--tRNA ligase [metG]. 2 573 37.412 T 29-03-2018 IPR023458 Methionine-tRNA ligase, type 1 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 SMALA_RS20165 186b9a451e15fc54a61ffc3dd3082b18 585 PRINTS PR01041 Methionyl-tRNA synthetase signature 87 98 1.1E-27 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 SMALA_RS20165 186b9a451e15fc54a61ffc3dd3082b18 585 PRINTS PR01041 Methionyl-tRNA synthetase signature 307 322 1.1E-27 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 SMALA_RS20165 186b9a451e15fc54a61ffc3dd3082b18 585 PRINTS PR01041 Methionyl-tRNA synthetase signature 401 412 1.1E-27 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 SMALA_RS20165 186b9a451e15fc54a61ffc3dd3082b18 585 PRINTS PR01041 Methionyl-tRNA synthetase signature 257 268 1.1E-27 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 SMALA_RS20165 186b9a451e15fc54a61ffc3dd3082b18 585 PRINTS PR01041 Methionyl-tRNA synthetase signature 39 53 1.1E-27 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 SMALA_RS20165 186b9a451e15fc54a61ffc3dd3082b18 585 PRINTS PR01041 Methionyl-tRNA synthetase signature 6 19 1.1E-27 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 SMALA_RS20165 186b9a451e15fc54a61ffc3dd3082b18 585 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 5 543 3.2E-143 T 29-03-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 SMALA_RS20165 186b9a451e15fc54a61ffc3dd3082b18 585 Gene3D G3DSA:2.20.28.20 139 162 4.6E-16 T 29-03-2018 SMALA_RS20165 186b9a451e15fc54a61ffc3dd3082b18 585 Pfam PF09334 tRNA synthetases class I (M) 4 414 5.7E-152 T 29-03-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMALA_RS20165 186b9a451e15fc54a61ffc3dd3082b18 585 SUPERFAMILY SSF47323 402 562 1.55E-33 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMALA_RS09590 60df50ae4605340122a0a962f520e03b 329 Pfam PF14527 WhiA LAGLIDADG-like domain 127 218 6.7E-24 T 29-03-2018 SMALA_RS09590 60df50ae4605340122a0a962f520e03b 329 Pfam PF10298 WhiA N-terminal LAGLIDADG-like domain 20 104 2.6E-25 T 29-03-2018 IPR018478 Sporulation transcription regulator WhiA, N-terminal domain SMALA_RS09590 60df50ae4605340122a0a962f520e03b 329 TIGRFAM TIGR00647 DNA_bind_WhiA: DNA-binding protein WhiA 4 304 5.0E-111 T 29-03-2018 IPR033981 Sporulation regulator WhiA-like SMALA_RS09590 60df50ae4605340122a0a962f520e03b 329 Hamap MF_01420 Putative sporulation transcription regulator WhiA [whiA]. 3 306 29.718 T 29-03-2018 IPR003802 Sporulation regulator WhiA GO:0043937 SMALA_RS09590 60df50ae4605340122a0a962f520e03b 329 Pfam PF02650 WhiA C-terminal HTH domain 221 303 1.3E-19 T 29-03-2018 IPR023054 Sporulation regulator WhiA, C-terminal SMALA_RS08210 9ad234ae9e6df5ccaa32f1feb82bf4fe 323 Pfam PF01040 UbiA prenyltransferase family 55 283 1.0E-20 T 29-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 SMALA_RS25690 be20c398c18a519b8c360381e9b71f4f 718 Pfam PF00326 Prolyl oligopeptidase family 516 717 7.0E-46 T 29-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 SMALA_RS25690 be20c398c18a519b8c360381e9b71f4f 718 Pfam PF00930 Dipeptidyl peptidase IV (DPP IV) N-terminal region 111 343 4.5E-30 T 29-03-2018 IPR002469 Dipeptidylpeptidase IV, N-terminal domain GO:0006508 SMALA_RS25690 be20c398c18a519b8c360381e9b71f4f 718 SUPERFAMILY SSF53474 471 717 4.15E-58 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS25690 be20c398c18a519b8c360381e9b71f4f 718 SUPERFAMILY SSF82171 19 343 1.57E-28 T 29-03-2018 SMALA_RS25690 be20c398c18a519b8c360381e9b71f4f 718 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 651 673 2.8E-5 T 29-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 SMALA_RS25690 be20c398c18a519b8c360381e9b71f4f 718 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 522 546 2.8E-5 T 29-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 SMALA_RS25690 be20c398c18a519b8c360381e9b71f4f 718 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 580 600 2.8E-5 T 29-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 SMALA_RS25690 be20c398c18a519b8c360381e9b71f4f 718 Gene3D G3DSA:3.40.50.1820 451 718 3.2E-39 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS25690 be20c398c18a519b8c360381e9b71f4f 718 Gene3D G3DSA:2.140.10.30 4 447 6.2E-49 T 29-03-2018 SMALA_RS25690 be20c398c18a519b8c360381e9b71f4f 718 ProSitePatterns PS00708 Prolyl endopeptidase family serine active site. 557 587 - T 29-03-2018 IPR002471 Peptidase S9, serine active site GO:0004252|GO:0006508 SMALA_RS30800 b1bb4ad9ce0656f78cee41a3af9a6526 1486 Gene3D G3DSA:3.40.50.300 1233 1478 1.4E-14 T 29-03-2018 SMALA_RS30800 b1bb4ad9ce0656f78cee41a3af9a6526 1486 SUPERFAMILY SSF56112 933 1166 9.25E-14 T 29-03-2018 IPR011009 Protein kinase-like domain SMALA_RS30800 b1bb4ad9ce0656f78cee41a3af9a6526 1486 SMART SM00220 935 1153 0.0066 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMALA_RS30800 b1bb4ad9ce0656f78cee41a3af9a6526 1486 SUPERFAMILY SSF52540 1235 1453 1.42E-14 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS30800 b1bb4ad9ce0656f78cee41a3af9a6526 1486 Gene3D G3DSA:1.10.510.10 931 1097 9.9E-11 T 29-03-2018 SMALA_RS30800 b1bb4ad9ce0656f78cee41a3af9a6526 1486 Gene3D G3DSA:1.10.510.10 1103 1175 0.047 T 29-03-2018 SMALA_RS30800 b1bb4ad9ce0656f78cee41a3af9a6526 1486 Gene3D G3DSA:1.10.510.10 647 818 0.013 T 29-03-2018 SMALA_RS08680 b0364462dfade2703607f5d097db6f85 384 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 246 260 - T 29-03-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 SMALA_RS08680 b0364462dfade2703607f5d097db6f85 384 Pfam PF00849 RNA pseudouridylate synthase 210 340 1.4E-23 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 SMALA_RS08680 b0364462dfade2703607f5d097db6f85 384 SMART SM00363 148 209 1.1E-9 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SMALA_RS08680 b0364462dfade2703607f5d097db6f85 384 Gene3D G3DSA:3.10.290.10 143 202 7.0E-18 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SMALA_RS08680 b0364462dfade2703607f5d097db6f85 384 SUPERFAMILY SSF55120 193 382 3.91E-43 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 SMALA_RS08680 b0364462dfade2703607f5d097db6f85 384 Gene3D G3DSA:3.30.70.580 203 289 2.5E-19 T 29-03-2018 SMALA_RS08680 b0364462dfade2703607f5d097db6f85 384 SUPERFAMILY SSF55174 123 212 4.71E-13 T 29-03-2018 SMALA_RS08680 b0364462dfade2703607f5d097db6f85 384 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 213 371 5.1E-43 T 29-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 SMALA_RS08680 b0364462dfade2703607f5d097db6f85 384 Gene3D G3DSA:3.30.70.1560 290 358 2.8E-17 T 29-03-2018 SMALA_RS08680 b0364462dfade2703607f5d097db6f85 384 Pfam PF01479 S4 domain 148 194 9.3E-14 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SMALA_RS04085 a6248049cb9e001db4be859284a04ed3 260 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 159 187 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMALA_RS04085 a6248049cb9e001db4be859284a04ed3 260 Pfam PF00106 short chain dehydrogenase 22 191 1.2E-23 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS04085 a6248049cb9e001db4be859284a04ed3 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 191 8.2E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS04085 a6248049cb9e001db4be859284a04ed3 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 98 109 8.2E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS04085 a6248049cb9e001db4be859284a04ed3 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 146 162 8.2E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS04085 a6248049cb9e001db4be859284a04ed3 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 22 39 8.2E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS04085 a6248049cb9e001db4be859284a04ed3 260 SUPERFAMILY SSF51735 16 253 2.29E-37 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS04085 a6248049cb9e001db4be859284a04ed3 260 Gene3D G3DSA:3.40.50.720 11 256 6.8E-40 T 29-03-2018 SMALA_RS02000 b44f9bb710c384b0284088969ffd3125 341 Gene3D G3DSA:1.10.260.40 14 66 2.8E-19 T 29-03-2018 SMALA_RS02000 b44f9bb710c384b0284088969ffd3125 341 SMART SM00354 12 81 2.1E-15 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS02000 b44f9bb710c384b0284088969ffd3125 341 SUPERFAMILY SSF47413 11 70 9.38E-15 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS02000 b44f9bb710c384b0284088969ffd3125 341 Gene3D G3DSA:3.40.50.2300 184 340 1.2E-38 T 29-03-2018 SMALA_RS02000 b44f9bb710c384b0284088969ffd3125 341 Pfam PF00356 Bacterial regulatory proteins, lacI family 14 59 3.0E-13 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS02000 b44f9bb710c384b0284088969ffd3125 341 SUPERFAMILY SSF53822 79 340 1.73E-54 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SMALA_RS02000 b44f9bb710c384b0284088969ffd3125 341 Gene3D G3DSA:3.40.50.2300 67 183 2.0E-26 T 29-03-2018 SMALA_RS02000 b44f9bb710c384b0284088969ffd3125 341 Pfam PF13377 Periplasmic binding protein-like domain 178 337 8.9E-35 T 29-03-2018 SMALA_RS09085 473bddaae8a395d80e457e01347c3e89 251 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 246 2.3E-41 T 29-03-2018 SMALA_RS09085 473bddaae8a395d80e457e01347c3e89 251 Gene3D G3DSA:3.40.50.720 1 246 2.7E-50 T 29-03-2018 SMALA_RS09085 473bddaae8a395d80e457e01347c3e89 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 3.6E-19 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS09085 473bddaae8a395d80e457e01347c3e89 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 3.6E-19 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS09085 473bddaae8a395d80e457e01347c3e89 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 3.6E-19 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS09085 473bddaae8a395d80e457e01347c3e89 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 3.6E-19 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS09085 473bddaae8a395d80e457e01347c3e89 251 SUPERFAMILY SSF51735 1 248 5.72E-61 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS08505 5f877aec17494220def0618439b7f2f4 154 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 10 89 9.7E-15 T 29-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 SMALA_RS08505 5f877aec17494220def0618439b7f2f4 154 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 11 141 8.4E-40 T 29-03-2018 IPR019920 F420-binding domain, putative SMALA_RS08505 5f877aec17494220def0618439b7f2f4 154 Gene3D G3DSA:2.30.110.10 1 147 3.9E-27 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS08505 5f877aec17494220def0618439b7f2f4 154 SUPERFAMILY SSF50475 10 143 2.99E-32 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS00265 3d1a808b4f1f024125f41027460b5ea4 306 Pfam PF00753 Metallo-beta-lactamase superfamily 70 280 5.4E-23 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS00265 3d1a808b4f1f024125f41027460b5ea4 306 SMART SM00849 69 280 5.6E-19 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS00265 3d1a808b4f1f024125f41027460b5ea4 306 Gene3D G3DSA:3.60.15.10 17 292 4.3E-46 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS00265 3d1a808b4f1f024125f41027460b5ea4 306 SUPERFAMILY SSF56281 44 299 1.44E-36 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS28145 834a85c84a8270a82a182fe6f7bfc2be 228 Gene3D G3DSA:2.40.30.60 2 91 9.2E-27 T 29-03-2018 IPR002676 RimM protein GO:0006364 SMALA_RS28145 834a85c84a8270a82a182fe6f7bfc2be 228 Pfam PF05239 PRC-barrel domain 94 166 1.1E-9 T 29-03-2018 IPR027275 PRC-barrel domain SMALA_RS28145 834a85c84a8270a82a182fe6f7bfc2be 228 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 2 166 23.236 T 29-03-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 SMALA_RS28145 834a85c84a8270a82a182fe6f7bfc2be 228 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 3 166 5.1E-42 T 29-03-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 SMALA_RS28145 834a85c84a8270a82a182fe6f7bfc2be 228 Gene3D G3DSA:2.30.30.240 92 161 2.8E-21 T 29-03-2018 SMALA_RS28145 834a85c84a8270a82a182fe6f7bfc2be 228 Pfam PF01782 RimM N-terminal domain 5 83 2.5E-22 T 29-03-2018 IPR002676 RimM protein GO:0006364 SMALA_RS28145 834a85c84a8270a82a182fe6f7bfc2be 228 SUPERFAMILY SSF50447 3 85 6.71E-18 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain SMALA_RS28145 834a85c84a8270a82a182fe6f7bfc2be 228 SUPERFAMILY SSF50346 96 166 8.83E-18 T 29-03-2018 IPR011033 PRC-barrel-like SMALA_RS32430 f0b4b866c3a5701ed54753c11cd1aa6b 342 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 3 342 1.2E-116 T 29-03-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 SMALA_RS32430 f0b4b866c3a5701ed54753c11cd1aa6b 342 Gene3D G3DSA:3.30.360.10 153 310 1.5E-54 T 29-03-2018 SMALA_RS32430 f0b4b866c3a5701ed54753c11cd1aa6b 342 Gene3D G3DSA:3.40.50.720 1 152 1.8E-41 T 29-03-2018 SMALA_RS32430 f0b4b866c3a5701ed54753c11cd1aa6b 342 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 4 129 8.0E-26 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 SMALA_RS32430 f0b4b866c3a5701ed54753c11cd1aa6b 342 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 155 313 1.7E-19 T 29-03-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 SMALA_RS32430 f0b4b866c3a5701ed54753c11cd1aa6b 342 SUPERFAMILY SSF55347 146 310 6.65E-47 T 29-03-2018 SMALA_RS32430 f0b4b866c3a5701ed54753c11cd1aa6b 342 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 3 336 37.858 T 29-03-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 SMALA_RS32430 f0b4b866c3a5701ed54753c11cd1aa6b 342 SMART SM00859 4 136 3.5E-42 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 SMALA_RS32430 f0b4b866c3a5701ed54753c11cd1aa6b 342 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 141 157 - T 29-03-2018 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 SMALA_RS32430 f0b4b866c3a5701ed54753c11cd1aa6b 342 SUPERFAMILY SSF51735 3 170 4.0E-45 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS40375 f5431c83c4c0fd44f084226f6694f1fb 547 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 218 236 2.0E-20 T 29-03-2018 SMALA_RS40375 f5431c83c4c0fd44f084226f6694f1fb 547 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 358 380 2.0E-20 T 29-03-2018 SMALA_RS40375 f5431c83c4c0fd44f084226f6694f1fb 547 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 59 78 2.0E-20 T 29-03-2018 SMALA_RS40375 f5431c83c4c0fd44f084226f6694f1fb 547 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 174 192 2.0E-20 T 29-03-2018 SMALA_RS40375 f5431c83c4c0fd44f084226f6694f1fb 547 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 328 344 2.0E-20 T 29-03-2018 SMALA_RS40375 f5431c83c4c0fd44f084226f6694f1fb 547 SUPERFAMILY SSF51905 58 400 5.1E-37 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS40375 f5431c83c4c0fd44f084226f6694f1fb 547 Gene3D G3DSA:3.50.50.60 218 429 5.5E-18 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS40375 f5431c83c4c0fd44f084226f6694f1fb 547 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 58 392 1.1E-25 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS40375 f5431c83c4c0fd44f084226f6694f1fb 547 Pfam PF04324 BFD-like [2Fe-2S] binding domain 445 495 6.9E-5 T 29-03-2018 IPR007419 BFD-like [2Fe-2S]-binding domain SMALA_RS40375 f5431c83c4c0fd44f084226f6694f1fb 547 PIRSF PIRSF037495 54 540 7.3E-118 T 29-03-2018 IPR017224 Opine oxidase, subunit A/hydrogen cyanide synthase, subunit B GO:0016491|GO:0055114 SMALA_RS40375 f5431c83c4c0fd44f084226f6694f1fb 547 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 177 186 2.8E-12 T 29-03-2018 SMALA_RS40375 f5431c83c4c0fd44f084226f6694f1fb 547 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 218 243 2.8E-12 T 29-03-2018 SMALA_RS40375 f5431c83c4c0fd44f084226f6694f1fb 547 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 373 380 2.8E-12 T 29-03-2018 SMALA_RS40375 f5431c83c4c0fd44f084226f6694f1fb 547 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 58 80 2.8E-12 T 29-03-2018 SMALA_RS40375 f5431c83c4c0fd44f084226f6694f1fb 547 Gene3D G3DSA:3.50.50.60 52 213 2.5E-21 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS08935 4203405e783ae13119bdc930df71f9f3 234 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 230 7.4E-64 T 29-03-2018 SMALA_RS08935 4203405e783ae13119bdc930df71f9f3 234 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 176 3.2E-9 T 29-03-2018 SMALA_RS08935 4203405e783ae13119bdc930df71f9f3 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 159 2.3E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS08935 4203405e783ae13119bdc930df71f9f3 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 67 78 2.3E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS08935 4203405e783ae13119bdc930df71f9f3 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 120 128 2.3E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS08935 4203405e783ae13119bdc930df71f9f3 234 SUPERFAMILY SSF51735 3 230 7.77E-84 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS08935 4203405e783ae13119bdc930df71f9f3 234 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 127 155 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMALA_RS08935 4203405e783ae13119bdc930df71f9f3 234 Gene3D G3DSA:3.40.50.720 2 145 5.4E-50 T 29-03-2018 SMALA_RS08935 4203405e783ae13119bdc930df71f9f3 234 Gene3D G3DSA:3.40.50.720 146 231 9.0E-28 T 29-03-2018 SMALA_RS08935 4203405e783ae13119bdc930df71f9f3 234 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 5 230 3.8E-95 T 29-03-2018 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 SMALA_RS08935 4203405e783ae13119bdc930df71f9f3 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 67 78 2.8E-46 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS08935 4203405e783ae13119bdc930df71f9f3 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 178 2.8E-46 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS08935 4203405e783ae13119bdc930df71f9f3 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 2.8E-46 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS08935 4203405e783ae13119bdc930df71f9f3 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 194 214 2.8E-46 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS08935 4203405e783ae13119bdc930df71f9f3 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 159 2.8E-46 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS08935 4203405e783ae13119bdc930df71f9f3 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 114 130 2.8E-46 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS28945 0d32147897ee570351985f84469c7ce8 627 Pfam PF04183 IucA / IucC family 165 398 5.6E-64 T 29-03-2018 IPR007310 Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal GO:0015343|GO:0019290 SMALA_RS28945 0d32147897ee570351985f84469c7ce8 627 Pfam PF06276 Ferric iron reductase FhuF-like transporter 433 594 4.1E-31 T 29-03-2018 IPR022770 Ferric iron reductase FhuF domain SMALA_RS38595 1d9895499dc5328ee178712ee955c0fb 613 Hamap MF_01659 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase [menD]. 42 602 33.648 T 29-03-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 SMALA_RS38595 1d9895499dc5328ee178712ee955c0fb 613 TIGRFAM TIGR00173 menD: 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase 49 475 8.0E-130 T 29-03-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 SMALA_RS38595 1d9895499dc5328ee178712ee955c0fb 613 Gene3D G3DSA:3.40.50.1220 245 395 1.4E-24 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain SMALA_RS38595 1d9895499dc5328ee178712ee955c0fb 613 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 49 211 1.2E-27 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 SMALA_RS38595 1d9895499dc5328ee178712ee955c0fb 613 Gene3D G3DSA:3.40.50.970 41 229 2.3E-48 T 29-03-2018 SMALA_RS38595 1d9895499dc5328ee178712ee955c0fb 613 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 448 583 2.6E-11 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 SMALA_RS38595 1d9895499dc5328ee178712ee955c0fb 613 Gene3D G3DSA:3.40.50.970 396 605 5.8E-34 T 29-03-2018 SMALA_RS38595 1d9895499dc5328ee178712ee955c0fb 613 Pfam PF16582 Middle domain of thiamine pyrophosphate 255 431 3.8E-16 T 29-03-2018 IPR032264 Menaquinone biosynthesis protein MenD, middle domain KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 SMALA_RS38595 1d9895499dc5328ee178712ee955c0fb 613 SUPERFAMILY SSF52518 49 228 5.4E-31 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold SMALA_RS38595 1d9895499dc5328ee178712ee955c0fb 613 SUPERFAMILY SSF52518 409 599 8.02E-26 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold SMALA_RS38595 1d9895499dc5328ee178712ee955c0fb 613 PIRSF PIRSF004983 44 608 6.8E-150 T 29-03-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 SMALA_RS42555 6db770d01c5944503f1f6cb35ae3155a 571 Gene3D G3DSA:3.40.190.10 214 320 2.2E-15 T 29-03-2018 SMALA_RS42555 6db770d01c5944503f1f6cb35ae3155a 571 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 100 471 3.0E-66 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain SMALA_RS42555 6db770d01c5944503f1f6cb35ae3155a 571 SUPERFAMILY SSF53850 53 567 1.23E-98 T 29-03-2018 SMALA_RS42555 6db770d01c5944503f1f6cb35ae3155a 571 Gene3D G3DSA:3.10.105.10 321 539 2.5E-40 T 29-03-2018 SMALA_RS42555 6db770d01c5944503f1f6cb35ae3155a 571 Gene3D G3DSA:3.90.76.10 68 204 1.5E-25 T 29-03-2018 SMALA_RS42555 6db770d01c5944503f1f6cb35ae3155a 571 PIRSF PIRSF002741 21 569 1.6E-70 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 SMALA_RS31915 2427a38b2cbeff05e979b1aaa8e6d198 98 SUPERFAMILY SSF54909 1 83 9.92E-17 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel SMALA_RS31915 2427a38b2cbeff05e979b1aaa8e6d198 98 Gene3D G3DSA:3.30.70.1060 1 84 2.1E-13 T 29-03-2018 SMALA_RS31915 2427a38b2cbeff05e979b1aaa8e6d198 98 Pfam PF03795 YCII-related domain 1 81 2.6E-10 T 29-03-2018 IPR005545 YCII-related SMALA_RS11785 ab3a4ebdcc9e4f342dc3fab70583997c 335 SUPERFAMILY SSF56436 82 327 2.28E-54 T 29-03-2018 IPR016187 C-type lectin fold SMALA_RS11785 ab3a4ebdcc9e4f342dc3fab70583997c 335 Gene3D G3DSA:3.90.1580.10 77 334 3.4E-49 T 29-03-2018 SMALA_RS11785 ab3a4ebdcc9e4f342dc3fab70583997c 335 Pfam PF03781 Sulfatase-modifying factor enzyme 1 114 325 1.7E-43 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 SMALA_RS35265 9aac136b0fc5b702f454be9ca0bad7f5 292 SUPERFAMILY SSF81338 24 272 5.63E-66 T 29-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 SMALA_RS35265 9aac136b0fc5b702f454be9ca0bad7f5 292 Pfam PF00230 Major intrinsic protein 24 268 1.8E-53 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMALA_RS35265 9aac136b0fc5b702f454be9ca0bad7f5 292 TIGRFAM TIGR00861 MIP: MIP family channel proteins 29 268 1.3E-65 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMALA_RS35265 9aac136b0fc5b702f454be9ca0bad7f5 292 PRINTS PR00783 Major intrinsic protein family signature 202 224 2.2E-49 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMALA_RS35265 9aac136b0fc5b702f454be9ca0bad7f5 292 PRINTS PR00783 Major intrinsic protein family signature 108 127 2.2E-49 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMALA_RS35265 9aac136b0fc5b702f454be9ca0bad7f5 292 PRINTS PR00783 Major intrinsic protein family signature 251 271 2.2E-49 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMALA_RS35265 9aac136b0fc5b702f454be9ca0bad7f5 292 PRINTS PR00783 Major intrinsic protein family signature 71 95 2.2E-49 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMALA_RS35265 9aac136b0fc5b702f454be9ca0bad7f5 292 PRINTS PR00783 Major intrinsic protein family signature 25 44 2.2E-49 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMALA_RS35265 9aac136b0fc5b702f454be9ca0bad7f5 292 PRINTS PR00783 Major intrinsic protein family signature 169 187 2.2E-49 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMALA_RS35265 9aac136b0fc5b702f454be9ca0bad7f5 292 ProSitePatterns PS00221 MIP family signature. 89 97 - T 29-03-2018 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMALA_RS35265 9aac136b0fc5b702f454be9ca0bad7f5 292 Gene3D G3DSA:1.20.1080.10 18 281 9.3E-74 T 29-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 SMALA_RS09475 4fcf22773da80c163a7fc1529981be16 389 TIGRFAM TIGR01981 sufD: FeS assembly protein SufD 107 376 1.0E-73 T 29-03-2018 IPR011542 SUF system FeS cluster assembly, SufD GO:0016226 SMALA_RS09475 4fcf22773da80c163a7fc1529981be16 389 Pfam PF01458 Uncharacterized protein family (UPF0051) 138 359 8.0E-71 T 29-03-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 SMALA_RS09475 4fcf22773da80c163a7fc1529981be16 389 SUPERFAMILY SSF101960 33 385 3.14E-93 T 29-03-2018 SMALA_RS09450 cb3c37468715b4debf687c140cf5c8b8 111 Pfam PF01883 Iron-sulfur cluster assembly protein 13 73 2.1E-19 T 29-03-2018 IPR002744 MIP18 family-like SMALA_RS09450 cb3c37468715b4debf687c140cf5c8b8 111 Gene3D G3DSA:3.30.300.130 9 106 3.3E-24 T 29-03-2018 IPR034904 Fe-S cluster assembly domain SMALA_RS09450 cb3c37468715b4debf687c140cf5c8b8 111 SUPERFAMILY SSF117916 11 105 2.52E-28 T 29-03-2018 IPR034904 Fe-S cluster assembly domain SMALA_RS37230 e3341438a252132c79d4038228492057 228 Gene3D G3DSA:1.10.10.10 152 216 8.8E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS37230 e3341438a252132c79d4038228492057 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 167 5.4E-5 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS37230 e3341438a252132c79d4038228492057 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 183 5.4E-5 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS37230 e3341438a252132c79d4038228492057 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 183 195 5.4E-5 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS37230 e3341438a252132c79d4038228492057 228 SMART SM00421 150 207 2.6E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS37230 e3341438a252132c79d4038228492057 228 SUPERFAMILY SSF46894 144 214 1.5E-13 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS37230 e3341438a252132c79d4038228492057 228 Pfam PF00196 Bacterial regulatory proteins, luxR family 152 206 7.7E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS37230 e3341438a252132c79d4038228492057 228 Pfam PF08448 PAS fold 32 124 5.6E-7 T 29-03-2018 IPR013656 PAS fold-4 SMALA_RS37230 e3341438a252132c79d4038228492057 228 SUPERFAMILY SSF55785 30 126 4.03E-8 T 29-03-2018 IPR000014 PAS domain SMALA_RS37230 e3341438a252132c79d4038228492057 228 Gene3D G3DSA:3.30.450.20 5 151 3.0E-10 T 29-03-2018 SMALA_RS07935 c94c26a9a237e2927d944c7ef62624d9 553 PIRSF PIRSF001294 4 553 2.9E-216 T 29-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 SMALA_RS07935 c94c26a9a237e2927d944c7ef62624d9 553 TIGRFAM TIGR00680 kdpA: K+-transporting ATPase, A subunit 5 552 1.8E-201 T 29-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 SMALA_RS07935 c94c26a9a237e2927d944c7ef62624d9 553 Hamap MF_00275 Potassium-transporting ATPase potassium-binding subunit [kdpA]. 4 553 32.249 T 29-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 SMALA_RS07935 c94c26a9a237e2927d944c7ef62624d9 553 Pfam PF03814 Potassium-transporting ATPase A subunit 14 552 7.1E-224 T 29-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 SMALA_RS40360 9feed2f19f417ffa759db93b2b281b98 192 SUPERFAMILY SSF51182 65 170 1.03E-14 T 29-03-2018 IPR011051 RmlC-like cupin domain SMALA_RS40360 9feed2f19f417ffa759db93b2b281b98 192 Pfam PF01381 Helix-turn-helix 6 60 2.2E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS40360 9feed2f19f417ffa759db93b2b281b98 192 Gene3D G3DSA:2.60.120.10 65 185 5.4E-13 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SMALA_RS40360 9feed2f19f417ffa759db93b2b281b98 192 Pfam PF07883 Cupin domain 109 166 1.7E-8 T 29-03-2018 IPR013096 Cupin 2, conserved barrel SMALA_RS40360 9feed2f19f417ffa759db93b2b281b98 192 SMART SM00530 5 60 7.9E-15 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS40360 9feed2f19f417ffa759db93b2b281b98 192 Gene3D G3DSA:1.10.260.40 1 64 1.1E-16 T 29-03-2018 SMALA_RS40360 9feed2f19f417ffa759db93b2b281b98 192 SUPERFAMILY SSF47413 2 63 4.5E-15 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS37620 8aee5a34f24f7ad836cf2b6549884978 172 SMART SM00960 15 106 2.9E-16 T 29-03-2018 IPR004942 Roadblock/LAMTOR2 domain SMALA_RS37620 8aee5a34f24f7ad836cf2b6549884978 172 SUPERFAMILY SSF103196 11 126 4.88E-21 T 29-03-2018 SMALA_RS37620 8aee5a34f24f7ad836cf2b6549884978 172 Gene3D G3DSA:3.30.450.30 1 128 1.7E-25 T 29-03-2018 SMALA_RS37620 8aee5a34f24f7ad836cf2b6549884978 172 Pfam PF03259 Roadblock/LC7 domain 21 105 7.8E-17 T 29-03-2018 IPR004942 Roadblock/LAMTOR2 domain SMALA_RS37485 f1dd06229115a7da3c4965af214813b6 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 6.9E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS37485 f1dd06229115a7da3c4965af214813b6 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 6.9E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS37485 f1dd06229115a7da3c4965af214813b6 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 139 158 6.9E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS37485 f1dd06229115a7da3c4965af214813b6 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 177 6.9E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS37485 f1dd06229115a7da3c4965af214813b6 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 195 215 6.9E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS37485 f1dd06229115a7da3c4965af214813b6 237 SUPERFAMILY SSF51735 5 231 6.18E-69 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS37485 f1dd06229115a7da3c4965af214813b6 237 Gene3D G3DSA:3.40.50.720 43 237 2.8E-55 T 29-03-2018 SMALA_RS37485 f1dd06229115a7da3c4965af214813b6 237 Gene3D G3DSA:3.40.50.720 1 42 2.9E-7 T 29-03-2018 SMALA_RS37485 f1dd06229115a7da3c4965af214813b6 237 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 231 6.8E-59 T 29-03-2018 SMALA_RS03290 ba569b819cd9b4488a46312b09035339 274 Gene3D G3DSA:3.10.310.10 1 129 7.3E-35 T 29-03-2018 SMALA_RS03290 ba569b819cd9b4488a46312b09035339 274 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 4 244 1.4E-39 T 29-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 SMALA_RS03290 ba569b819cd9b4488a46312b09035339 274 Gene3D G3DSA:3.10.310.10 130 263 4.4E-33 T 29-03-2018 SMALA_RS03290 ba569b819cd9b4488a46312b09035339 274 PIRSF PIRSF016184 1 274 8.2E-51 T 29-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 SMALA_RS03290 ba569b819cd9b4488a46312b09035339 274 Pfam PF02567 Phenazine biosynthesis-like protein 6 270 9.5E-63 T 29-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 SMALA_RS03290 ba569b819cd9b4488a46312b09035339 274 SUPERFAMILY SSF54506 2 272 1.54E-70 T 29-03-2018 SMALA_RS11765 b4d1ac799439a3b812230706d298e015 172 Gene3D G3DSA:2.60.120.10 28 164 4.6E-23 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SMALA_RS11765 b4d1ac799439a3b812230706d298e015 172 Pfam PF07883 Cupin domain 65 127 1.5E-15 T 29-03-2018 IPR013096 Cupin 2, conserved barrel SMALA_RS11765 b4d1ac799439a3b812230706d298e015 172 SUPERFAMILY SSF51182 24 142 2.35E-26 T 29-03-2018 IPR011051 RmlC-like cupin domain SMALA_RS35855 373360b39a2c2ba61e9a188454e45624 247 Pfam PF11575 FhuF 2Fe-2S C-terminal domain 218 238 6.3E-10 T 29-03-2018 IPR024726 Ferric iron reductase, C-terminal GO:0051537 SMALA_RS18700 2a85ccc0229e2fd86833aebda811406f 134 SUPERFAMILY SSF101386 37 87 5.42E-11 T 29-03-2018 SMALA_RS18700 2a85ccc0229e2fd86833aebda811406f 134 Gene3D G3DSA:1.10.3420.10 1 42 1.7E-7 T 29-03-2018 SMALA_RS18700 2a85ccc0229e2fd86833aebda811406f 134 Gene3D G3DSA:1.10.3420.10 43 131 8.3E-34 T 29-03-2018 SMALA_RS18700 2a85ccc0229e2fd86833aebda811406f 134 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 9 91 1.6E-26 T 29-03-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 SMALA_RS07175 85c081314f0f7b750f103c958035aaa8 260 Gene3D G3DSA:2.60.40.10 2 79 1.2E-9 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS07175 85c081314f0f7b750f103c958035aaa8 260 SUPERFAMILY SSF81296 3 80 3.92E-10 T 29-03-2018 IPR014756 Immunoglobulin E-set SMALA_RS07175 85c081314f0f7b750f103c958035aaa8 260 Gene3D G3DSA:2.60.40.10 175 260 7.3E-7 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS07175 85c081314f0f7b750f103c958035aaa8 260 Gene3D G3DSA:2.60.40.10 82 174 1.8E-7 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS03890 26f0d543413994c73499aa83c8a924bf 815 SUPERFAMILY SSF53474 611 721 1.64E-9 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS03890 26f0d543413994c73499aa83c8a924bf 815 Gene3D G3DSA:3.40.50.1820 549 790 1.0E-15 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS03585 0d7e9dc97c351c3b754ce3a488d3e080 301 SMART SM00797 27 300 2.8E-96 T 29-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B SMALA_RS03585 0d7e9dc97c351c3b754ce3a488d3e080 301 SUPERFAMILY SSF50891 176 289 2.96E-14 T 29-03-2018 IPR029000 Cyclophilin-like domain SMALA_RS03585 0d7e9dc97c351c3b754ce3a488d3e080 301 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 28 284 5.0E-83 T 29-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B SMALA_RS03585 0d7e9dc97c351c3b754ce3a488d3e080 301 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 8 286 3.3E-77 T 29-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B SMALA_RS25515 c21bcda3cc3bb2d77c4584731c5589e7 250 Pfam PF07702 UTRA domain 111 242 2.4E-10 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMALA_RS25515 c21bcda3cc3bb2d77c4584731c5589e7 250 SUPERFAMILY SSF46785 4 79 3.33E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS25515 c21bcda3cc3bb2d77c4584731c5589e7 250 Gene3D G3DSA:3.40.1410.10 77 245 6.5E-29 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMALA_RS25515 c21bcda3cc3bb2d77c4584731c5589e7 250 SUPERFAMILY SSF64288 59 248 4.08E-21 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMALA_RS25515 c21bcda3cc3bb2d77c4584731c5589e7 250 SMART SM00866 99 242 4.3E-4 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMALA_RS25515 c21bcda3cc3bb2d77c4584731c5589e7 250 SMART SM00345 12 71 8.4E-12 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS25515 c21bcda3cc3bb2d77c4584731c5589e7 250 Gene3D G3DSA:1.10.10.10 4 73 1.1E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS25515 c21bcda3cc3bb2d77c4584731c5589e7 250 Pfam PF00392 Bacterial regulatory proteins, gntR family 9 71 2.8E-15 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS12430 dcffba2d23491dd69fb284efea5b1a0b 457 Gene3D G3DSA:3.30.565.10 47 306 6.6E-13 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS12430 dcffba2d23491dd69fb284efea5b1a0b 457 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 199 306 1.4E-6 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS12430 dcffba2d23491dd69fb284efea5b1a0b 457 SUPERFAMILY SSF55874 183 307 3.41E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS30460 dc60b07784af91612594ab2c4fc8e6d2 799 Gene3D G3DSA:3.30.365.10 184 290 9.9E-31 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMALA_RS30460 dc60b07784af91612594ab2c4fc8e6d2 799 TIGRFAM TIGR03196 pucD: xanthine dehydrogenase D subunit 26 796 1.0E-246 T 29-03-2018 IPR017609 Xanthine dehydrogenase D subunit KEGG: 00230+1.17.1.4|MetaCyc: PWY-5497|MetaCyc: PWY-5695|MetaCyc: PWY-6538|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-6999 SMALA_RS30460 dc60b07784af91612594ab2c4fc8e6d2 799 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 175 740 6.1E-146 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMALA_RS30460 dc60b07784af91612594ab2c4fc8e6d2 799 Gene3D G3DSA:3.30.365.10 291 445 1.0E-43 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMALA_RS30460 dc60b07784af91612594ab2c4fc8e6d2 799 Gene3D G3DSA:3.90.1170.50 4 144 1.7E-37 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMALA_RS30460 dc60b07784af91612594ab2c4fc8e6d2 799 SUPERFAMILY SSF56003 136 796 1.7E-150 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMALA_RS30460 dc60b07784af91612594ab2c4fc8e6d2 799 Gene3D G3DSA:3.30.365.10 638 798 6.8E-43 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMALA_RS30460 dc60b07784af91612594ab2c4fc8e6d2 799 SUPERFAMILY SSF54665 21 164 1.31E-43 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMALA_RS30460 dc60b07784af91612594ab2c4fc8e6d2 799 SMART SM01008 38 144 3.0E-49 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMALA_RS30460 dc60b07784af91612594ab2c4fc8e6d2 799 Gene3D G3DSA:3.30.365.10 476 637 1.6E-25 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMALA_RS30460 dc60b07784af91612594ab2c4fc8e6d2 799 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 38 144 1.1E-32 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMALA_RS30390 f1fb323e147f997edff01638ef8597ee 164 SUPERFAMILY SSF89623 9 156 4.05E-36 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 SMALA_RS30390 f1fb323e147f997edff01638ef8597ee 164 PIRSF PIRSF005384 10 159 6.5E-34 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 SMALA_RS30390 f1fb323e147f997edff01638ef8597ee 164 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 12 157 8.8E-26 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 SMALA_RS30390 f1fb323e147f997edff01638ef8597ee 164 Gene3D G3DSA:3.40.1400.10 8 161 2.6E-41 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 SMALA_RS30390 f1fb323e147f997edff01638ef8597ee 164 Pfam PF02502 Ribose/Galactose Isomerase 12 152 7.7E-34 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 SMALA_RS04915 9df93a2b7fdac11187167240cf8fdfa1 386 Gene3D G3DSA:3.40.50.720 2 175 9.3E-40 T 29-03-2018 SMALA_RS04915 9df93a2b7fdac11187167240cf8fdfa1 386 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 245 267 - T 29-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site SMALA_RS04915 9df93a2b7fdac11187167240cf8fdfa1 386 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 195 222 - T 29-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 SMALA_RS04915 9df93a2b7fdac11187167240cf8fdfa1 386 SUPERFAMILY SSF51735 147 336 1.1E-50 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS04915 9df93a2b7fdac11187167240cf8fdfa1 386 Gene3D G3DSA:3.40.50.720 176 336 8.6E-39 T 29-03-2018 SMALA_RS04915 9df93a2b7fdac11187167240cf8fdfa1 386 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 62 362 8.5E-17 T 29-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 SMALA_RS04915 9df93a2b7fdac11187167240cf8fdfa1 386 Hamap MF_03210 Formate dehydrogenase, mitochondrial. 2 383 56.169 T 29-03-2018 IPR033689 NAD-dependent formate dehydrogenase GO:0008863 KEGG: 00630+1.2.1.2|KEGG: 00680+1.2.1.2|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696 SMALA_RS04915 9df93a2b7fdac11187167240cf8fdfa1 386 SUPERFAMILY SSF52283 3 173 3.83E-62 T 29-03-2018 SMALA_RS04915 9df93a2b7fdac11187167240cf8fdfa1 386 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 156 335 4.2E-46 T 29-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 SMALA_RS29690 66bef0b0dcab0621a50185e2500a610b 311 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 106 307 1.1E-13 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS29690 66bef0b0dcab0621a50185e2500a610b 311 Gene3D G3DSA:1.10.3720.10 31 310 2.1E-48 T 29-03-2018 SMALA_RS29690 66bef0b0dcab0621a50185e2500a610b 311 SUPERFAMILY SSF161098 73 298 1.96E-59 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS20940 21b6ce328c011235d93fd6f7e2a503e0 362 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 77 91 6.4E-20 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 SMALA_RS20940 21b6ce328c011235d93fd6f7e2a503e0 362 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 143 165 6.4E-20 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 SMALA_RS20940 21b6ce328c011235d93fd6f7e2a503e0 362 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 299 310 6.4E-20 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 SMALA_RS20940 21b6ce328c011235d93fd6f7e2a503e0 362 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 187 207 6.4E-20 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 SMALA_RS20940 21b6ce328c011235d93fd6f7e2a503e0 362 SUPERFAMILY SSF53223 17 155 2.56E-42 T 29-03-2018 SMALA_RS20940 21b6ce328c011235d93fd6f7e2a503e0 362 SMART SM00839 155 361 7.8E-41 T 29-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 SMALA_RS20940 21b6ce328c011235d93fd6f7e2a503e0 362 SUPERFAMILY SSF51735 152 358 3.04E-44 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS20940 21b6ce328c011235d93fd6f7e2a503e0 362 Gene3D G3DSA:3.40.50.720 155 349 2.3E-28 T 29-03-2018 SMALA_RS20940 21b6ce328c011235d93fd6f7e2a503e0 362 Gene3D G3DSA:3.40.50.10860 13 154 1.3E-47 T 29-03-2018 SMALA_RS20940 21b6ce328c011235d93fd6f7e2a503e0 362 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 226 306 6.4E-8 T 29-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 SMALA_RS20940 21b6ce328c011235d93fd6f7e2a503e0 362 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 85 98 - T 29-03-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 SMALA_RS20940 21b6ce328c011235d93fd6f7e2a503e0 362 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 24 141 2.1E-25 T 29-03-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 SMALA_RS20940 21b6ce328c011235d93fd6f7e2a503e0 362 PIRSF PIRSF000188 8 362 8.2E-140 T 29-03-2018 IPR016211 Glutamate/phenylalanine/leucine/valine dehydrogenase, bacterial/archaeal GO:0016639|GO:0055114 SMALA_RS01005 658e89717b84b7db38f2aa1ab001636e 499 Gene3D G3DSA:2.130.10.130 296 474 3.3E-15 T 29-03-2018 SMALA_RS01005 658e89717b84b7db38f2aa1ab001636e 499 Gene3D G3DSA:2.130.10.130 30 149 9.7E-8 T 29-03-2018 SMALA_RS01005 658e89717b84b7db38f2aa1ab001636e 499 Gene3D G3DSA:2.130.10.130 150 295 1.0E-11 T 29-03-2018 SMALA_RS01005 658e89717b84b7db38f2aa1ab001636e 499 Pfam PF01839 FG-GAP repeat 141 173 3.4E-6 T 29-03-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 SMALA_RS01005 658e89717b84b7db38f2aa1ab001636e 499 SUPERFAMILY SSF69318 69 460 7.41E-30 T 29-03-2018 SMALA_RS10625 65f5016fbe615442c0675a5f64fd6a13 250 Pfam PF08241 Methyltransferase domain 37 137 1.2E-18 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 SMALA_RS10625 65f5016fbe615442c0675a5f64fd6a13 250 Gene3D G3DSA:3.40.50.150 7 250 1.8E-39 T 29-03-2018 SMALA_RS10625 65f5016fbe615442c0675a5f64fd6a13 250 SUPERFAMILY SSF53335 20 237 1.81E-33 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS04910 ed55756eb84eeb591d7ca10aee628a28 349 Gene3D G3DSA:3.20.20.140 6 320 3.2E-49 T 29-03-2018 SMALA_RS04910 ed55756eb84eeb591d7ca10aee628a28 349 Pfam PF04909 Amidohydrolase 8 309 4.7E-35 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 SMALA_RS04910 ed55756eb84eeb591d7ca10aee628a28 349 SUPERFAMILY SSF51556 7 309 7.99E-68 T 29-03-2018 IPR032466 Metal-dependent hydrolase SMALA_RS27580 f7ba3ed80e36d967393632f8ee3a9c0c 292 SUPERFAMILY SSF55961 163 287 5.5E-18 T 29-03-2018 SMALA_RS27580 f7ba3ed80e36d967393632f8ee3a9c0c 292 SUPERFAMILY SSF55961 8 150 9.17E-41 T 29-03-2018 SMALA_RS27580 f7ba3ed80e36d967393632f8ee3a9c0c 292 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 23 133 2.3E-23 T 29-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 SMALA_RS27580 f7ba3ed80e36d967393632f8ee3a9c0c 292 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 180 285 2.6E-7 T 29-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 SMALA_RS27580 f7ba3ed80e36d967393632f8ee3a9c0c 292 Gene3D G3DSA:3.30.530.20 158 289 4.4E-14 T 29-03-2018 IPR023393 START-like domain SMALA_RS27580 f7ba3ed80e36d967393632f8ee3a9c0c 292 Gene3D G3DSA:3.30.530.20 2 157 2.8E-35 T 29-03-2018 IPR023393 START-like domain SMALA_RS05395 cabcf35d83358d02ac5c9e6e384a4e34 427 SUPERFAMILY SSF103473 5 396 5.75E-46 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS05395 cabcf35d83358d02ac5c9e6e384a4e34 427 Gene3D G3DSA:1.20.1250.20 206 401 5.7E-22 T 29-03-2018 SMALA_RS05395 cabcf35d83358d02ac5c9e6e384a4e34 427 Gene3D G3DSA:1.20.1250.20 2 195 1.2E-16 T 29-03-2018 SMALA_RS05395 cabcf35d83358d02ac5c9e6e384a4e34 427 Pfam PF07690 Major Facilitator Superfamily 10 345 4.5E-29 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS14580 13fa974426d33ab67e66de092e90609b 254 Gene3D G3DSA:3.40.50.1860 11 123 2.5E-6 T 29-03-2018 SMALA_RS14580 13fa974426d33ab67e66de092e90609b 254 Gene3D G3DSA:3.40.50.2300 124 240 0.0016 T 29-03-2018 SMALA_RS14580 13fa974426d33ab67e66de092e90609b 254 Pfam PF01177 Asp/Glu/Hydantoin racemase 66 231 8.9E-8 T 29-03-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMALA_RS08355 d82638009700b31a439b0c0182c20e32 468 SUPERFAMILY SSF51445 93 235 3.99E-32 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS08355 d82638009700b31a439b0c0182c20e32 468 SUPERFAMILY SSF51445 270 372 3.99E-32 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS08355 d82638009700b31a439b0c0182c20e32 468 Gene3D G3DSA:3.20.20.80 55 411 1.4E-25 T 29-03-2018 SMALA_RS38085 56543d06825600d8432e73fb706c3c46 233 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 160 1.1E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS38085 56543d06825600d8432e73fb706c3c46 233 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 70 81 1.1E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS38085 56543d06825600d8432e73fb706c3c46 233 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 123 131 1.1E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS38085 56543d06825600d8432e73fb706c3c46 233 SUPERFAMILY SSF51735 5 204 3.4E-48 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS38085 56543d06825600d8432e73fb706c3c46 233 Pfam PF00106 short chain dehydrogenase 8 185 1.3E-32 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS38085 56543d06825600d8432e73fb706c3c46 233 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 70 81 9.2E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS38085 56543d06825600d8432e73fb706c3c46 233 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 117 133 9.2E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS38085 56543d06825600d8432e73fb706c3c46 233 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 141 160 9.2E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS38085 56543d06825600d8432e73fb706c3c46 233 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 179 9.2E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS38085 56543d06825600d8432e73fb706c3c46 233 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 9.2E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS38085 56543d06825600d8432e73fb706c3c46 233 Gene3D G3DSA:3.40.50.720 4 212 1.7E-47 T 29-03-2018 SMALA_RS18340 48be7fa6ecdf214dcf979979943a4f33 118 Pfam PF05239 PRC-barrel domain 7 75 3.4E-7 T 29-03-2018 IPR027275 PRC-barrel domain SMALA_RS18340 48be7fa6ecdf214dcf979979943a4f33 118 Gene3D G3DSA:3.90.50.10 2 112 2.5E-14 T 29-03-2018 SMALA_RS18340 48be7fa6ecdf214dcf979979943a4f33 118 SUPERFAMILY SSF50346 5 107 1.28E-15 T 29-03-2018 IPR011033 PRC-barrel-like SMALA_RS37310 ca0467f06be628c0f83b68b087324e5d 500 Gene3D G3DSA:3.50.50.60 417 496 9.8E-9 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS37310 ca0467f06be628c0f83b68b087324e5d 500 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 146 319 1.8E-18 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS37310 ca0467f06be628c0f83b68b087324e5d 500 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 400 470 1.3E-7 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS37310 ca0467f06be628c0f83b68b087324e5d 500 Gene3D G3DSA:1.10.1060.10 4 144 5.0E-38 T 29-03-2018 SMALA_RS37310 ca0467f06be628c0f83b68b087324e5d 500 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 41 131 2.1E-20 T 29-03-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 SMALA_RS37310 ca0467f06be628c0f83b68b087324e5d 500 Gene3D G3DSA:3.40.50.720 145 241 4.8E-22 T 29-03-2018 SMALA_RS37310 ca0467f06be628c0f83b68b087324e5d 500 Gene3D G3DSA:3.50.50.60 242 356 7.2E-26 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS37310 ca0467f06be628c0f83b68b087324e5d 500 SUPERFAMILY SSF46548 5 155 1.26E-34 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 SMALA_RS37310 ca0467f06be628c0f83b68b087324e5d 500 PRINTS PR00419 Adrenodoxin reductase family signature 169 182 2.0E-23 T 29-03-2018 SMALA_RS37310 ca0467f06be628c0f83b68b087324e5d 500 PRINTS PR00419 Adrenodoxin reductase family signature 211 221 2.0E-23 T 29-03-2018 SMALA_RS37310 ca0467f06be628c0f83b68b087324e5d 500 PRINTS PR00419 Adrenodoxin reductase family signature 285 299 2.0E-23 T 29-03-2018 SMALA_RS37310 ca0467f06be628c0f83b68b087324e5d 500 PRINTS PR00419 Adrenodoxin reductase family signature 146 168 2.0E-23 T 29-03-2018 SMALA_RS37310 ca0467f06be628c0f83b68b087324e5d 500 TIGRFAM TIGR01317 GOGAT_sm_gam: glutamate synthase, NADH/NADPH, small subunit 3 488 1.4E-194 T 29-03-2018 IPR006005 Glutamate synthase, NADH/NADPH, small subunit 1 GO:0006537|GO:0016639|GO:0055114 SMALA_RS37310 ca0467f06be628c0f83b68b087324e5d 500 SUPERFAMILY SSF51971 398 414 1.57E-58 T 29-03-2018 SMALA_RS37310 ca0467f06be628c0f83b68b087324e5d 500 SUPERFAMILY SSF51971 143 369 1.57E-58 T 29-03-2018 SMALA_RS11350 c4f16bfe80dbb6384dbac11d8fe49c7a 299 Pfam PF02591 C4-type zinc ribbon domain 257 291 2.4E-9 T 29-03-2018 IPR003743 C4-type zinc ribbon domain SMALA_RS11350 c4f16bfe80dbb6384dbac11d8fe49c7a 299 Gene3D G3DSA:1.20.120.330 68 232 3.7E-8 T 29-03-2018 SMALA_RS29830 03c1831951a51c041501ade96cbe50c4 425 Pfam PF01612 3'-5' exonuclease 44 204 2.3E-33 T 29-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 SMALA_RS29830 03c1831951a51c041501ade96cbe50c4 425 Gene3D G3DSA:1.10.150.80 228 335 2.2E-32 T 29-03-2018 SMALA_RS29830 03c1831951a51c041501ade96cbe50c4 425 SMART SM00341 244 325 8.1E-17 T 29-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 SMALA_RS29830 03c1831951a51c041501ade96cbe50c4 425 Pfam PF00570 HRDC domain 247 313 4.0E-14 T 29-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 SMALA_RS29830 03c1831951a51c041501ade96cbe50c4 425 SMART SM00474 39 205 3.0E-38 T 29-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 SMALA_RS29830 03c1831951a51c041501ade96cbe50c4 425 SUPERFAMILY SSF53098 27 242 2.55E-50 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SMALA_RS29830 03c1831951a51c041501ade96cbe50c4 425 SUPERFAMILY SSF47819 225 336 5.89E-26 T 29-03-2018 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 SMALA_RS29830 03c1831951a51c041501ade96cbe50c4 425 Gene3D G3DSA:3.30.420.10 31 227 1.3E-30 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SMALA_RS01075 9c0b3a8eda6d532a40403777f1418bcf 749 SUPERFAMILY SSF52540 7 153 1.74E-33 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS01075 9c0b3a8eda6d532a40403777f1418bcf 749 SUPERFAMILY SSF52540 276 415 1.74E-33 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS01075 9c0b3a8eda6d532a40403777f1418bcf 749 Gene3D G3DSA:3.40.50.300 449 749 1.9E-54 T 29-03-2018 SMALA_RS01075 9c0b3a8eda6d532a40403777f1418bcf 749 Pfam PF00005 ABC transporter 464 666 7.1E-10 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS01075 9c0b3a8eda6d532a40403777f1418bcf 749 SUPERFAMILY SSF52540 457 719 4.7E-39 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS01075 9c0b3a8eda6d532a40403777f1418bcf 749 Gene3D G3DSA:1.20.1580.10 98 123 1.5E-7 T 29-03-2018 SMALA_RS01075 9c0b3a8eda6d532a40403777f1418bcf 749 Gene3D G3DSA:1.20.1580.10 124 319 1.3E-42 T 29-03-2018 SMALA_RS01075 9c0b3a8eda6d532a40403777f1418bcf 749 Gene3D G3DSA:3.40.50.300 320 432 3.9E-23 T 29-03-2018 SMALA_RS01075 9c0b3a8eda6d532a40403777f1418bcf 749 Gene3D G3DSA:3.40.50.300 1 97 9.2E-7 T 29-03-2018 SMALA_RS12555 9a4282e485d66b5828c6eb97ec8e74fd 460 Pfam PF02627 Carboxymuconolactone decarboxylase family 338 419 8.4E-24 T 29-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SMALA_RS12555 9a4282e485d66b5828c6eb97ec8e74fd 460 SUPERFAMILY SSF53474 7 255 4.67E-55 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS12555 9a4282e485d66b5828c6eb97ec8e74fd 460 PRINTS PR00111 Alpha/beta hydrolase fold signature 90 103 3.3E-10 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS12555 9a4282e485d66b5828c6eb97ec8e74fd 460 PRINTS PR00111 Alpha/beta hydrolase fold signature 104 117 3.3E-10 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS12555 9a4282e485d66b5828c6eb97ec8e74fd 460 PRINTS PR00111 Alpha/beta hydrolase fold signature 42 57 3.3E-10 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS12555 9a4282e485d66b5828c6eb97ec8e74fd 460 PRINTS PR00111 Alpha/beta hydrolase fold signature 201 215 3.3E-10 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS12555 9a4282e485d66b5828c6eb97ec8e74fd 460 Pfam PF00561 alpha/beta hydrolase fold 17 136 4.7E-13 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS12555 9a4282e485d66b5828c6eb97ec8e74fd 460 Pfam PF08386 TAP-like protein 197 260 2.4E-7 T 29-03-2018 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal SMALA_RS12555 9a4282e485d66b5828c6eb97ec8e74fd 460 TIGRFAM TIGR02427 protocat_pcaD: 3-oxoadipate enol-lactonase 7 256 6.5E-78 T 29-03-2018 IPR026968 3-oxoadipate enol-lactonase 1/2 GO:0042952|GO:0047570 KEGG: 00362+3.1.1.24|MetaCyc: PWY-6185 SMALA_RS12555 9a4282e485d66b5828c6eb97ec8e74fd 460 SUPERFAMILY SSF69118 305 428 8.77E-35 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 SMALA_RS12555 9a4282e485d66b5828c6eb97ec8e74fd 460 Gene3D G3DSA:1.20.1290.10 312 457 6.3E-35 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 SMALA_RS12555 9a4282e485d66b5828c6eb97ec8e74fd 460 Gene3D G3DSA:3.40.50.1820 6 259 1.2E-43 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS12555 9a4282e485d66b5828c6eb97ec8e74fd 460 TIGRFAM TIGR02425 decarb_PcaC: 4-carboxymuconolactone decarboxylase 306 425 2.9E-50 T 29-03-2018 IPR012788 4-carboxymuconolactone decarboxylase KEGG: 00362+4.1.1.44 SMALA_RS20210 eb7a7e43ad2b1c93c741db9029f43475 916 Pfam PF01590 GAF domain 452 533 3.3E-8 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS20210 eb7a7e43ad2b1c93c741db9029f43475 916 Gene3D G3DSA:3.30.450.20 231 362 9.8E-10 T 29-03-2018 SMALA_RS20210 eb7a7e43ad2b1c93c741db9029f43475 916 Gene3D G3DSA:3.30.450.20 67 204 5.9E-24 T 29-03-2018 SMALA_RS20210 eb7a7e43ad2b1c93c741db9029f43475 916 Gene3D G3DSA:3.60.40.10 540 792 4.3E-49 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS20210 eb7a7e43ad2b1c93c741db9029f43475 916 SUPERFAMILY SSF103190 73 203 1.65E-34 T 29-03-2018 IPR029151 Periplasmic sensor domain-like SMALA_RS20210 eb7a7e43ad2b1c93c741db9029f43475 916 SMART SM00065 373 543 1.3E-6 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS20210 eb7a7e43ad2b1c93c741db9029f43475 916 SUPERFAMILY SSF55874 831 911 9.2E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS20210 eb7a7e43ad2b1c93c741db9029f43475 916 Gene3D G3DSA:3.30.450.40 369 539 7.3E-34 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS20210 eb7a7e43ad2b1c93c741db9029f43475 916 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 588 789 3.5E-55 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS20210 eb7a7e43ad2b1c93c741db9029f43475 916 SUPERFAMILY SSF55781 443 544 1.26E-15 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS20210 eb7a7e43ad2b1c93c741db9029f43475 916 Gene3D G3DSA:3.30.565.10 793 916 6.5E-13 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS20210 eb7a7e43ad2b1c93c741db9029f43475 916 Pfam PF17203 Single cache domain 3 71 199 5.9E-27 T 29-03-2018 IPR033463 Single cache domain 3 SMALA_RS20210 eb7a7e43ad2b1c93c741db9029f43475 916 SMART SM00331 564 789 6.6E-44 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS20210 eb7a7e43ad2b1c93c741db9029f43475 916 Pfam PF13581 Histidine kinase-like ATPase domain 802 910 5.9E-9 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS20210 eb7a7e43ad2b1c93c741db9029f43475 916 SUPERFAMILY SSF81606 576 788 3.4E-9 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS33965 a188092f70e469196a4dc6d6c0163e0d 275 Gene3D G3DSA:1.10.3720.10 6 270 3.8E-41 T 29-03-2018 SMALA_RS33965 a188092f70e469196a4dc6d6c0163e0d 275 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 261 2.2E-19 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS33965 a188092f70e469196a4dc6d6c0163e0d 275 SUPERFAMILY SSF161098 6 274 1.18E-59 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS33170 60606f1218210a35c51e7b4c6c4e8517 318 SUPERFAMILY SSF56601 62 290 1.22E-27 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMALA_RS33170 60606f1218210a35c51e7b4c6c4e8517 318 Gene3D G3DSA:3.40.710.10 58 292 4.6E-17 T 29-03-2018 SMALA_RS33170 60606f1218210a35c51e7b4c6c4e8517 318 Pfam PF13354 Beta-lactamase enzyme family 129 266 7.3E-11 T 29-03-2018 SMALA_RS31855 9e16016b75643c9db4b10f6ac3fdf1a3 514 Gene3D G3DSA:3.30.560.10 358 469 1.1E-26 T 29-03-2018 SMALA_RS31855 9e16016b75643c9db4b10f6ac3fdf1a3 514 Gene3D G3DSA:3.30.560.10 103 357 2.6E-61 T 29-03-2018 SMALA_RS31855 9e16016b75643c9db4b10f6ac3fdf1a3 514 SUPERFAMILY SSF54373 293 455 2.06E-41 T 29-03-2018 SMALA_RS31855 9e16016b75643c9db4b10f6ac3fdf1a3 514 SUPERFAMILY SSF51905 3 286 5.51E-68 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS31855 9e16016b75643c9db4b10f6ac3fdf1a3 514 SUPERFAMILY SSF51905 451 513 5.51E-68 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS31855 9e16016b75643c9db4b10f6ac3fdf1a3 514 Gene3D G3DSA:4.10.450.10 38 102 2.8E-14 T 29-03-2018 SMALA_RS31855 9e16016b75643c9db4b10f6ac3fdf1a3 514 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 257 271 - T 29-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 SMALA_RS31855 9e16016b75643c9db4b10f6ac3fdf1a3 514 PIRSF PIRSF000137 1 319 2.9E-84 T 29-03-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 SMALA_RS31855 9e16016b75643c9db4b10f6ac3fdf1a3 514 PIRSF PIRSF000137 318 514 1.9E-42 T 29-03-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 SMALA_RS31855 9e16016b75643c9db4b10f6ac3fdf1a3 514 Pfam PF05199 GMC oxidoreductase 370 507 5.7E-36 T 29-03-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 SMALA_RS31855 9e16016b75643c9db4b10f6ac3fdf1a3 514 Pfam PF00732 GMC oxidoreductase 4 299 2.9E-73 T 29-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 SMALA_RS33465 62851e05c7eb66105a05a66d87153fc7 218 ProSitePatterns PS00622 LuxR-type HTH domain signature. 168 195 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS33465 62851e05c7eb66105a05a66d87153fc7 218 Pfam PF00072 Response regulator receiver domain 4 113 7.3E-28 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS33465 62851e05c7eb66105a05a66d87153fc7 218 SMART SM00421 151 208 4.1E-23 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS33465 62851e05c7eb66105a05a66d87153fc7 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 184 196 1.4E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS33465 62851e05c7eb66105a05a66d87153fc7 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 168 1.4E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS33465 62851e05c7eb66105a05a66d87153fc7 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 184 1.4E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS33465 62851e05c7eb66105a05a66d87153fc7 218 SUPERFAMILY SSF52172 3 132 1.57E-32 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS33465 62851e05c7eb66105a05a66d87153fc7 218 Gene3D G3DSA:1.10.10.10 127 218 2.7E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS33465 62851e05c7eb66105a05a66d87153fc7 218 SUPERFAMILY SSF46894 145 214 6.46E-20 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS33465 62851e05c7eb66105a05a66d87153fc7 218 SMART SM00448 2 115 1.5E-31 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS33465 62851e05c7eb66105a05a66d87153fc7 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 207 9.7E-17 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS33465 62851e05c7eb66105a05a66d87153fc7 218 Gene3D G3DSA:3.40.50.2300 1 126 4.3E-35 T 29-03-2018 SMALA_RS32395 d7f70a15d79e1ef7855f36488de26cf4 410 SUPERFAMILY SSF51445 37 336 3.63E-20 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS32395 d7f70a15d79e1ef7855f36488de26cf4 410 Pfam PF02638 Glycosyl hydrolase-like 10 38 352 4.2E-82 T 29-03-2018 IPR003790 Glycosyl hydrolase-like 10 SMALA_RS32395 d7f70a15d79e1ef7855f36488de26cf4 410 Gene3D G3DSA:3.20.20.80 43 384 3.2E-37 T 29-03-2018 SMALA_RS11050 a29cddae28ab71dc77bc84fdb4d77ef5 311 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 225 294 1.0E-17 T 29-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMALA_RS11050 a29cddae28ab71dc77bc84fdb4d77ef5 311 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 229 245 - T 29-03-2018 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMALA_RS11050 a29cddae28ab71dc77bc84fdb4d77ef5 311 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 6 210 2.2E-52 T 29-03-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMALA_RS11050 a29cddae28ab71dc77bc84fdb4d77ef5 311 Gene3D G3DSA:3.40.190.10 108 197 9.6E-29 T 29-03-2018 SMALA_RS11050 a29cddae28ab71dc77bc84fdb4d77ef5 311 Gene3D G3DSA:3.30.160.40 221 305 1.7E-24 T 29-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMALA_RS11050 a29cddae28ab71dc77bc84fdb4d77ef5 311 PIRSF PIRSF001438 1 310 6.9E-86 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMALA_RS11050 a29cddae28ab71dc77bc84fdb4d77ef5 311 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 6 295 1.4E-77 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMALA_RS11050 a29cddae28ab71dc77bc84fdb4d77ef5 311 SUPERFAMILY SSF53850 3 215 3.15E-53 T 29-03-2018 SMALA_RS11050 a29cddae28ab71dc77bc84fdb4d77ef5 311 SUPERFAMILY SSF54782 224 308 1.7E-21 T 29-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMALA_RS11050 a29cddae28ab71dc77bc84fdb4d77ef5 311 Gene3D G3DSA:3.40.190.10 1 107 8.9E-26 T 29-03-2018 SMALA_RS11050 a29cddae28ab71dc77bc84fdb4d77ef5 311 PRINTS PR00151 Porphobilinogen deaminase signature 77 96 3.2E-26 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMALA_RS11050 a29cddae28ab71dc77bc84fdb4d77ef5 311 PRINTS PR00151 Porphobilinogen deaminase signature 228 245 3.2E-26 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMALA_RS11050 a29cddae28ab71dc77bc84fdb4d77ef5 311 PRINTS PR00151 Porphobilinogen deaminase signature 122 139 3.2E-26 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMALA_RS11050 a29cddae28ab71dc77bc84fdb4d77ef5 311 PRINTS PR00151 Porphobilinogen deaminase signature 141 158 3.2E-26 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMALA_RS12895 822ac29b541c2ade90a90530b22c5504 116 SUPERFAMILY SSF53927 12 111 1.88E-9 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 SMALA_RS12895 822ac29b541c2ade90a90530b22c5504 116 Gene3D G3DSA:3.40.140.10 5 115 4.2E-9 T 29-03-2018 SMALA_RS03075 856a3dff9324b19b208c9a6128a685e4 479 Pfam PF00324 Amino acid permease 37 443 9.3E-104 T 29-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 SMALA_RS03075 856a3dff9324b19b208c9a6128a685e4 479 PIRSF PIRSF006060 7 477 6.1E-62 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMALA_RS03075 856a3dff9324b19b208c9a6128a685e4 479 ProSitePatterns PS00218 Amino acid permeases signature. 62 92 - T 29-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 SMALA_RS23875 2595df6d8b3cc08abedad1a79e71656a 436 Gene3D G3DSA:3.40.710.10 2 436 2.0E-82 T 29-03-2018 SMALA_RS23875 2595df6d8b3cc08abedad1a79e71656a 436 SUPERFAMILY SSF56601 9 53 2.33E-61 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMALA_RS23875 2595df6d8b3cc08abedad1a79e71656a 436 SUPERFAMILY SSF56601 91 427 2.33E-61 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMALA_RS23875 2595df6d8b3cc08abedad1a79e71656a 436 Pfam PF00144 Beta-lactamase 19 423 1.0E-64 T 29-03-2018 IPR001466 Beta-lactamase-related SMALA_RS00370 5bda9a79905efbc6c70b5810e641aa33 1120 SMART SM01260 729 1111 8.8E-54 T 29-03-2018 IPR007822 Lanthionine synthetase C-like SMALA_RS00370 5bda9a79905efbc6c70b5810e641aa33 1120 TIGRFAM TIGR03897 lanti_2_LanM: type 2 lantibiotic biosynthesis protein LanM 125 1102 1.4E-204 T 29-03-2018 IPR017146 Type 2 lantibiotic biosynthesis protein LanM SMALA_RS00370 5bda9a79905efbc6c70b5810e641aa33 1120 Pfam PF13575 Domain of unknown function (DUF4135) 218 611 2.1E-105 T 29-03-2018 IPR025410 Lantibiotic biosynthesis protein, dehydration domain SMALA_RS00370 5bda9a79905efbc6c70b5810e641aa33 1120 PIRSF PIRSF037228 164 1117 2.4E-155 T 29-03-2018 IPR017146 Type 2 lantibiotic biosynthesis protein LanM SMALA_RS00370 5bda9a79905efbc6c70b5810e641aa33 1120 Pfam PF05147 Lanthionine synthetase C-like protein 730 1111 3.6E-46 T 29-03-2018 IPR007822 Lanthionine synthetase C-like SMALA_RS00370 5bda9a79905efbc6c70b5810e641aa33 1120 PRINTS PR01950 LanC-like protein superfamily signature 968 988 2.2E-13 T 29-03-2018 IPR007822 Lanthionine synthetase C-like SMALA_RS00370 5bda9a79905efbc6c70b5810e641aa33 1120 PRINTS PR01950 LanC-like protein superfamily signature 732 750 2.2E-13 T 29-03-2018 IPR007822 Lanthionine synthetase C-like SMALA_RS00370 5bda9a79905efbc6c70b5810e641aa33 1120 PRINTS PR01950 LanC-like protein superfamily signature 1083 1100 2.2E-13 T 29-03-2018 IPR007822 Lanthionine synthetase C-like SMALA_RS00370 5bda9a79905efbc6c70b5810e641aa33 1120 PRINTS PR01950 LanC-like protein superfamily signature 844 859 2.2E-13 T 29-03-2018 IPR007822 Lanthionine synthetase C-like SMALA_RS00370 5bda9a79905efbc6c70b5810e641aa33 1120 PRINTS PR01950 LanC-like protein superfamily signature 908 924 2.2E-13 T 29-03-2018 IPR007822 Lanthionine synthetase C-like SMALA_RS00370 5bda9a79905efbc6c70b5810e641aa33 1120 SUPERFAMILY SSF158745 710 1115 1.44E-56 T 29-03-2018 SMALA_RS00370 5bda9a79905efbc6c70b5810e641aa33 1120 Gene3D G3DSA:1.50.10.10 850 1074 0.065 T 29-03-2018 SMALA_RS00370 5bda9a79905efbc6c70b5810e641aa33 1120 Gene3D G3DSA:1.50.10.10 682 849 8.5E-4 T 29-03-2018 SMALA_RS00370 5bda9a79905efbc6c70b5810e641aa33 1120 PRINTS PR01955 Frankia sp. LanC-like protein signature 843 859 1.3E-6 T 29-03-2018 SMALA_RS00370 5bda9a79905efbc6c70b5810e641aa33 1120 PRINTS PR01955 Frankia sp. LanC-like protein signature 1029 1049 1.3E-6 T 29-03-2018 SMALA_RS00370 5bda9a79905efbc6c70b5810e641aa33 1120 PRINTS PR01955 Frankia sp. LanC-like protein signature 733 748 1.3E-6 T 29-03-2018 SMALA_RS00370 5bda9a79905efbc6c70b5810e641aa33 1120 PRINTS PR01955 Frankia sp. LanC-like protein signature 905 929 1.3E-6 T 29-03-2018 SMALA_RS00370 5bda9a79905efbc6c70b5810e641aa33 1120 PRINTS PR01955 Frankia sp. LanC-like protein signature 1084 1101 1.3E-6 T 29-03-2018 SMALA_RS42625 59b5d03ec62f0ca6957bedd05560b89a 236 Gene3D G3DSA:2.120.10.70 84 236 2.3E-5 T 29-03-2018 SMALA_RS42625 59b5d03ec62f0ca6957bedd05560b89a 236 SMART SM00706 2 36 3.5E-4 T 29-03-2018 IPR006624 Beta-propeller repeat TECPR SMALA_RS42625 59b5d03ec62f0ca6957bedd05560b89a 236 SMART SM00706 79 113 0.0084 T 29-03-2018 IPR006624 Beta-propeller repeat TECPR SMALA_RS42625 59b5d03ec62f0ca6957bedd05560b89a 236 SMART SM00706 157 191 0.0011 T 29-03-2018 IPR006624 Beta-propeller repeat TECPR SMALA_RS42625 59b5d03ec62f0ca6957bedd05560b89a 236 SMART SM00706 198 232 1.7E-4 T 29-03-2018 IPR006624 Beta-propeller repeat TECPR SMALA_RS42625 59b5d03ec62f0ca6957bedd05560b89a 236 SMART SM00706 40 74 0.0017 T 29-03-2018 IPR006624 Beta-propeller repeat TECPR SMALA_RS42625 59b5d03ec62f0ca6957bedd05560b89a 236 SMART SM00706 117 151 0.0038 T 29-03-2018 IPR006624 Beta-propeller repeat TECPR SMALA_RS42625 59b5d03ec62f0ca6957bedd05560b89a 236 SUPERFAMILY SSF89372 17 229 3.92E-9 T 29-03-2018 SMALA_RS17275 4bb7306d02766693ed8b3daf553d2442 544 Pfam PF00561 alpha/beta hydrolase fold 105 265 1.2E-24 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS17275 4bb7306d02766693ed8b3daf553d2442 544 Pfam PF08386 TAP-like protein 418 516 7.5E-21 T 29-03-2018 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal SMALA_RS17275 4bb7306d02766693ed8b3daf553d2442 544 SUPERFAMILY SSF53474 79 149 1.4E-23 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS17275 4bb7306d02766693ed8b3daf553d2442 544 SUPERFAMILY SSF53474 387 490 1.4E-23 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS17275 4bb7306d02766693ed8b3daf553d2442 544 SUPERFAMILY SSF53474 177 269 1.4E-23 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS17275 4bb7306d02766693ed8b3daf553d2442 544 Gene3D G3DSA:3.40.50.1820 15 506 7.1E-45 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS20870 c62941f3e7075321969837a4fd3c8c68 306 SUPERFAMILY SSF56104 12 305 3.92E-98 T 29-03-2018 SMALA_RS20870 c62941f3e7075321969837a4fd3c8c68 306 Gene3D G3DSA:3.30.470.20 113 254 2.2E-55 T 29-03-2018 SMALA_RS20870 c62941f3e7075321969837a4fd3c8c68 306 Pfam PF01259 SAICAR synthetase 19 275 6.4E-100 T 29-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SMALA_RS20870 c62941f3e7075321969837a4fd3c8c68 306 Gene3D G3DSA:3.30.200.20 14 112 3.5E-38 T 29-03-2018 SMALA_RS20870 c62941f3e7075321969837a4fd3c8c68 306 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 18 304 4.8E-66 T 29-03-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 SMALA_RS20870 c62941f3e7075321969837a4fd3c8c68 306 ProSitePatterns PS01058 SAICAR synthetase signature 2. 204 212 - T 29-03-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SMALA_RS20870 c62941f3e7075321969837a4fd3c8c68 306 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 16 302 25.216 T 29-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SMALA_RS20870 c62941f3e7075321969837a4fd3c8c68 306 ProSitePatterns PS01057 SAICAR synthetase signature 1. 105 119 - T 29-03-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SMALA_RS16080 5d81460226a0b9e84a4790715388f1a2 508 Pfam PF00221 Aromatic amino acid lyase 31 463 1.2E-117 T 29-03-2018 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 SMALA_RS16080 5d81460226a0b9e84a4790715388f1a2 508 Gene3D G3DSA:1.10.275.10 22 216 7.0E-52 T 29-03-2018 IPR024083 Fumarase/histidase, N-terminal SMALA_RS16080 5d81460226a0b9e84a4790715388f1a2 508 Gene3D G3DSA:1.20.200.10 217 507 8.4E-83 T 29-03-2018 SMALA_RS16080 5d81460226a0b9e84a4790715388f1a2 508 SUPERFAMILY SSF48557 20 504 5.65E-115 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 SMALA_RS27680 bd288ec9b92402780fa5556d1d514634 766 Pfam PF03176 MMPL family 459 701 3.1E-27 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 SMALA_RS27680 bd288ec9b92402780fa5556d1d514634 766 Pfam PF03176 MMPL family 42 372 6.0E-67 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 SMALA_RS27680 bd288ec9b92402780fa5556d1d514634 766 SUPERFAMILY SSF82866 124 335 2.35E-29 T 29-03-2018 SMALA_RS27680 bd288ec9b92402780fa5556d1d514634 766 Gene3D G3DSA:1.20.1640.10 470 697 5.7E-28 T 29-03-2018 SMALA_RS27680 bd288ec9b92402780fa5556d1d514634 766 Gene3D G3DSA:1.20.1640.10 134 346 2.5E-32 T 29-03-2018 SMALA_RS27680 bd288ec9b92402780fa5556d1d514634 766 SUPERFAMILY SSF82866 470 701 1.44E-23 T 29-03-2018 SMALA_RS03735 7e359fa12f047d0eee881cb889b63fd9 142 Gene3D G3DSA:1.10.10.60 12 66 7.9E-15 T 29-03-2018 SMALA_RS03735 7e359fa12f047d0eee881cb889b63fd9 142 Gene3D G3DSA:1.10.10.60 67 124 4.6E-15 T 29-03-2018 SMALA_RS03735 7e359fa12f047d0eee881cb889b63fd9 142 SMART SM00342 26 109 5.4E-30 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS03735 7e359fa12f047d0eee881cb889b63fd9 142 Pfam PF12833 Helix-turn-helix domain 32 111 2.6E-22 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS03735 7e359fa12f047d0eee881cb889b63fd9 142 SUPERFAMILY SSF46689 62 113 2.6E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS03735 7e359fa12f047d0eee881cb889b63fd9 142 SUPERFAMILY SSF46689 11 60 1.08E-9 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS34300 ada071ddc6a9dd19c78fb38d5876ff72 554 SMART SM00387 411 547 9.9E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS34300 ada071ddc6a9dd19c78fb38d5876ff72 554 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 315 362 7.0E-11 T 29-03-2018 SMALA_RS34300 ada071ddc6a9dd19c78fb38d5876ff72 554 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 413 536 1.0E-12 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS34300 ada071ddc6a9dd19c78fb38d5876ff72 554 Pfam PF17203 Single cache domain 3 25 160 8.4E-12 T 29-03-2018 IPR033463 Single cache domain 3 SMALA_RS34300 ada071ddc6a9dd19c78fb38d5876ff72 554 Gene3D G3DSA:3.30.565.10 375 552 5.1E-24 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS34300 ada071ddc6a9dd19c78fb38d5876ff72 554 Gene3D G3DSA:3.30.450.20 19 149 1.6E-11 T 29-03-2018 SMALA_RS34300 ada071ddc6a9dd19c78fb38d5876ff72 554 SUPERFAMILY SSF55890 324 363 1.7E-10 T 29-03-2018 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 SMALA_RS34300 ada071ddc6a9dd19c78fb38d5876ff72 554 Gene3D G3DSA:1.10.287.130 313 368 3.7E-18 T 29-03-2018 SMALA_RS34300 ada071ddc6a9dd19c78fb38d5876ff72 554 SUPERFAMILY SSF55785 215 316 5.82E-6 T 29-03-2018 IPR000014 PAS domain SMALA_RS34300 ada071ddc6a9dd19c78fb38d5876ff72 554 SUPERFAMILY SSF103190 30 149 2.9E-11 T 29-03-2018 IPR029151 Periplasmic sensor domain-like SMALA_RS34300 ada071ddc6a9dd19c78fb38d5876ff72 554 SUPERFAMILY SSF55874 380 537 3.54E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS34300 ada071ddc6a9dd19c78fb38d5876ff72 554 Gene3D G3DSA:3.30.450.20 195 312 6.7E-12 T 29-03-2018 SMALA_RS34300 ada071ddc6a9dd19c78fb38d5876ff72 554 SMART SM00091 204 269 0.0023 T 29-03-2018 IPR000014 PAS domain SMALA_RS01025 af214e4c58c64ba50f25db975d92e173 512 Pfam PF00355 Rieske [2Fe-2S] domain 461 500 2.2E-8 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMALA_RS01025 af214e4c58c64ba50f25db975d92e173 512 Gene3D G3DSA:2.102.10.10 334 508 1.3E-11 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMALA_RS01025 af214e4c58c64ba50f25db975d92e173 512 Gene3D G3DSA:3.60.15.10 1 270 9.7E-15 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS01025 af214e4c58c64ba50f25db975d92e173 512 SUPERFAMILY SSF56281 1 76 8.96E-14 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS01025 af214e4c58c64ba50f25db975d92e173 512 SUPERFAMILY SSF56281 105 228 8.96E-14 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS01025 af214e4c58c64ba50f25db975d92e173 512 SUPERFAMILY SSF50022 461 507 1.44E-11 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMALA_RS01025 af214e4c58c64ba50f25db975d92e173 512 Pfam PF13483 Beta-lactamase superfamily domain 3 82 6.0E-7 T 29-03-2018 SMALA_RS33190 57b702c44a683d3f0d6549e436886a8e 178 SUPERFAMILY SSF55961 14 160 9.37E-41 T 29-03-2018 SMALA_RS33190 57b702c44a683d3f0d6549e436886a8e 178 Gene3D G3DSA:3.30.530.20 4 171 4.1E-30 T 29-03-2018 IPR023393 START-like domain SMALA_RS33190 57b702c44a683d3f0d6549e436886a8e 178 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 27 158 1.9E-23 T 29-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 SMALA_RS02205 5bce0ac0d651f3518339a6558f2633d4 685 SMART SM01086 572 665 3.2E-4 T 29-03-2018 IPR019489 Clp ATPase, C-terminal SMALA_RS02205 5bce0ac0d651f3518339a6558f2633d4 685 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 575 653 4.8E-7 T 29-03-2018 IPR019489 Clp ATPase, C-terminal SMALA_RS02205 5bce0ac0d651f3518339a6558f2633d4 685 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 466 484 3.4E-27 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 SMALA_RS02205 5bce0ac0d651f3518339a6558f2633d4 685 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 392 410 3.4E-27 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 SMALA_RS02205 5bce0ac0d651f3518339a6558f2633d4 685 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 437 455 3.4E-27 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 SMALA_RS02205 5bce0ac0d651f3518339a6558f2633d4 685 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 499 513 3.4E-27 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 SMALA_RS02205 5bce0ac0d651f3518339a6558f2633d4 685 Pfam PF07724 AAA domain (Cdc48 subfamily) 388 562 3.6E-36 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 SMALA_RS02205 5bce0ac0d651f3518339a6558f2633d4 685 Gene3D G3DSA:1.10.8.60 573 661 7.1E-8 T 29-03-2018 SMALA_RS02205 5bce0ac0d651f3518339a6558f2633d4 685 SUPERFAMILY SSF52540 341 640 2.05E-50 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS02205 5bce0ac0d651f3518339a6558f2633d4 685 SMART SM00382 388 557 2.8E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS02205 5bce0ac0d651f3518339a6558f2633d4 685 Gene3D G3DSA:3.40.50.300 338 570 2.8E-36 T 29-03-2018 SMALA_RS40795 2f830795f4d6240fe8bc4d745246375e 299 Gene3D G3DSA:1.10.3720.10 27 292 7.1E-43 T 29-03-2018 SMALA_RS40795 2f830795f4d6240fe8bc4d745246375e 299 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 70 133 1.7E-13 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 SMALA_RS40795 2f830795f4d6240fe8bc4d745246375e 299 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 288 3.2E-22 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS40795 2f830795f4d6240fe8bc4d745246375e 299 SUPERFAMILY SSF161098 71 274 2.49E-40 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS30685 551ccf6dd408a64659397a1119c87cda 307 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 68 285 3.2E-44 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SMALA_RS30685 551ccf6dd408a64659397a1119c87cda 307 Gene3D G3DSA:3.40.190.10 57 170 6.1E-25 T 29-03-2018 SMALA_RS30685 551ccf6dd408a64659397a1119c87cda 307 SMART SM00062 67 291 9.0E-53 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SMALA_RS30685 551ccf6dd408a64659397a1119c87cda 307 Gene3D G3DSA:3.40.190.10 171 256 6.0E-21 T 29-03-2018 SMALA_RS30685 551ccf6dd408a64659397a1119c87cda 307 SUPERFAMILY SSF53850 57 285 7.22E-52 T 29-03-2018 SMALA_RS30685 551ccf6dd408a64659397a1119c87cda 307 SUPERFAMILY SSF53850 9 27 7.22E-52 T 29-03-2018 SMALA_RS26490 7b7a059afe64d39125990f5492b733e1 320 Gene3D G3DSA:3.90.180.10 4 320 7.3E-61 T 29-03-2018 SMALA_RS26490 7b7a059afe64d39125990f5492b733e1 320 SUPERFAMILY SSF51735 129 294 4.06E-37 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS26490 7b7a059afe64d39125990f5492b733e1 320 SMART SM00829 13 318 1.1E-11 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS26490 7b7a059afe64d39125990f5492b733e1 320 Pfam PF00107 Zinc-binding dehydrogenase 165 283 5.6E-17 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMALA_RS26490 7b7a059afe64d39125990f5492b733e1 320 SUPERFAMILY SSF50129 6 154 6.13E-30 T 29-03-2018 IPR011032 GroES-like SMALA_RS01265 20512f804e3bb411c263f8e9c2f25a45 300 Gene3D G3DSA:3.40.190.10 176 267 1.7E-18 T 29-03-2018 SMALA_RS01265 20512f804e3bb411c263f8e9c2f25a45 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 4.8E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS01265 20512f804e3bb411c263f8e9c2f25a45 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 4.8E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS01265 20512f804e3bb411c263f8e9c2f25a45 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 4.8E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS01265 20512f804e3bb411c263f8e9c2f25a45 300 Gene3D G3DSA:3.40.190.10 89 175 4.1E-17 T 29-03-2018 SMALA_RS01265 20512f804e3bb411c263f8e9c2f25a45 300 Gene3D G3DSA:1.10.10.10 2 83 4.3E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS01265 20512f804e3bb411c263f8e9c2f25a45 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 7.2E-22 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS01265 20512f804e3bb411c263f8e9c2f25a45 300 Pfam PF03466 LysR substrate binding domain 88 293 1.8E-33 T 29-03-2018 IPR005119 LysR, substrate-binding SMALA_RS01265 20512f804e3bb411c263f8e9c2f25a45 300 SUPERFAMILY SSF46785 3 86 2.21E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS01265 20512f804e3bb411c263f8e9c2f25a45 300 SUPERFAMILY SSF53850 89 297 3.44E-31 T 29-03-2018 SMALA_RS13920 7219490a9f2f4e17b8627d24a284f0eb 237 SUPERFAMILY SSF46689 33 105 4.84E-19 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS13920 7219490a9f2f4e17b8627d24a284f0eb 237 Pfam PF00440 Bacterial regulatory proteins, tetR family 47 92 1.4E-15 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS13920 7219490a9f2f4e17b8627d24a284f0eb 237 Gene3D G3DSA:1.10.260.40 69 94 5.2E-13 T 29-03-2018 SMALA_RS13920 7219490a9f2f4e17b8627d24a284f0eb 237 Gene3D G3DSA:1.10.10.60 23 68 1.2E-16 T 29-03-2018 SMALA_RS13920 7219490a9f2f4e17b8627d24a284f0eb 237 Gene3D G3DSA:1.10.357.10 95 230 3.6E-7 T 29-03-2018 SMALA_RS13920 7219490a9f2f4e17b8627d24a284f0eb 237 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 68 91 5.9E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS13920 7219490a9f2f4e17b8627d24a284f0eb 237 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 47 60 5.9E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS13920 7219490a9f2f4e17b8627d24a284f0eb 237 ProSitePatterns PS01081 TetR-type HTH domain signature. 59 89 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site SMALA_RS00840 c3c2e6b446cc6a0cdf089275ee598cf2 553 Pfam PF00795 Carbon-nitrogen hydrolase 307 496 5.5E-9 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMALA_RS00840 c3c2e6b446cc6a0cdf089275ee598cf2 553 SUPERFAMILY SSF56317 300 507 1.7E-28 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMALA_RS00840 c3c2e6b446cc6a0cdf089275ee598cf2 553 Gene3D G3DSA:3.60.110.10 250 503 2.9E-26 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMALA_RS41890 72e19865a9a9f6f2d84beeb9151e9e19 200 SUPERFAMILY SSF48498 90 199 2.02E-10 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS41890 72e19865a9a9f6f2d84beeb9151e9e19 200 Gene3D G3DSA:1.10.10.60 1 44 7.9E-10 T 29-03-2018 SMALA_RS41890 72e19865a9a9f6f2d84beeb9151e9e19 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 28 69 2.4E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS41890 72e19865a9a9f6f2d84beeb9151e9e19 200 Gene3D G3DSA:1.10.260.40 45 74 1.4E-8 T 29-03-2018 SMALA_RS41890 72e19865a9a9f6f2d84beeb9151e9e19 200 SUPERFAMILY SSF46689 14 85 2.14E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS41890 72e19865a9a9f6f2d84beeb9151e9e19 200 Gene3D G3DSA:1.10.357.10 75 200 1.8E-17 T 29-03-2018 SMALA_RS35655 c160a030214c980c0635ab995f4c17fd 404 SUPERFAMILY SSF89796 10 404 5.62E-104 T 29-03-2018 IPR023606 CoA-transferase family III domain SMALA_RS35655 c160a030214c980c0635ab995f4c17fd 404 Pfam PF02515 CoA-transferase family III 12 380 1.7E-105 T 29-03-2018 IPR003673 CoA-transferase family III GO:0003824 SMALA_RS35655 c160a030214c980c0635ab995f4c17fd 404 Gene3D G3DSA:3.40.50.10540 7 404 1.1E-107 T 29-03-2018 IPR023606 CoA-transferase family III domain SMALA_RS38640 4d5d93962030b4301b6c1835a7b42e8c 778 Pfam PF14498 Glycosyl hydrolase family 65, N-terminal domain 106 247 7.8E-21 T 29-03-2018 IPR027414 Glycosyl hydrolase family 95, N-terminal domain KEGG: 00511+3.2.1.51 SMALA_RS38640 4d5d93962030b4301b6c1835a7b42e8c 778 Pfam PF14498 Glycosyl hydrolase family 65, N-terminal domain 42 93 9.5E-7 T 29-03-2018 IPR027414 Glycosyl hydrolase family 95, N-terminal domain KEGG: 00511+3.2.1.51 SMALA_RS38640 4d5d93962030b4301b6c1835a7b42e8c 778 PIRSF PIRSF007663 15 777 7.4E-202 T 29-03-2018 IPR016518 Alpha-L-fucosidase GO:0004560 KEGG: 00511+3.2.1.51 SMALA_RS38640 4d5d93962030b4301b6c1835a7b42e8c 778 Gene3D G3DSA:2.60.40.1180 686 775 2.3E-29 T 29-03-2018 SMALA_RS38640 4d5d93962030b4301b6c1835a7b42e8c 778 Gene3D G3DSA:1.50.10.10 219 685 1.2E-106 T 29-03-2018 SMALA_RS38640 4d5d93962030b4301b6c1835a7b42e8c 778 SUPERFAMILY SSF48208 260 759 2.32E-55 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 SMALA_RS23010 ef73b7042ade785c9b37f7505a2510ae 405 Pfam PF02371 Transposase IS116/IS110/IS902 family 275 358 8.6E-25 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 SMALA_RS23010 ef73b7042ade785c9b37f7505a2510ae 405 Pfam PF01548 Transposase 11 166 1.5E-44 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 SMALA_RS26135 66b9da36ad0b5784c610944b5e1cb8e3 494 Pfam PF00199 Catalase 18 399 3.8E-187 T 29-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMALA_RS26135 66b9da36ad0b5784c610944b5e1cb8e3 494 Gene3D G3DSA:2.40.180.10 2 368 1.2E-164 T 29-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMALA_RS26135 66b9da36ad0b5784c610944b5e1cb8e3 494 PRINTS PR00067 Catalase signature 299 326 2.9E-68 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMALA_RS26135 66b9da36ad0b5784c610944b5e1cb8e3 494 PRINTS PR00067 Catalase signature 94 112 2.9E-68 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMALA_RS26135 66b9da36ad0b5784c610944b5e1cb8e3 494 PRINTS PR00067 Catalase signature 31 54 2.9E-68 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMALA_RS26135 66b9da36ad0b5784c610944b5e1cb8e3 494 PRINTS PR00067 Catalase signature 115 132 2.9E-68 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMALA_RS26135 66b9da36ad0b5784c610944b5e1cb8e3 494 PRINTS PR00067 Catalase signature 134 152 2.9E-68 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMALA_RS26135 66b9da36ad0b5784c610944b5e1cb8e3 494 PRINTS PR00067 Catalase signature 331 357 2.9E-68 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMALA_RS26135 66b9da36ad0b5784c610944b5e1cb8e3 494 PIRSF PIRSF038928 6 493 2.1E-219 T 29-03-2018 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMALA_RS26135 66b9da36ad0b5784c610944b5e1cb8e3 494 SMART SM01060 18 402 1.6E-281 T 29-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMALA_RS26135 66b9da36ad0b5784c610944b5e1cb8e3 494 ProSitePatterns PS00438 Catalase proximal active site signature. 54 70 - T 29-03-2018 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMALA_RS26135 66b9da36ad0b5784c610944b5e1cb8e3 494 Pfam PF06628 Catalase-related immune-responsive 428 489 9.7E-21 T 29-03-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMALA_RS26135 66b9da36ad0b5784c610944b5e1cb8e3 494 SUPERFAMILY SSF56634 14 490 4.84E-206 T 29-03-2018 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMALA_RS26135 66b9da36ad0b5784c610944b5e1cb8e3 494 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 344 352 - T 29-03-2018 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 SMALA_RS36255 94c2be1f1070cf64163b9b5604b9e7b0 333 Gene3D G3DSA:1.10.10.10 84 184 3.4E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS36255 94c2be1f1070cf64163b9b5604b9e7b0 333 Gene3D G3DSA:3.10.450.50 185 326 1.1E-25 T 29-03-2018 SMALA_RS36255 94c2be1f1070cf64163b9b5604b9e7b0 333 Pfam PF04542 Sigma-70 region 2 18 83 6.1E-21 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS36255 94c2be1f1070cf64163b9b5604b9e7b0 333 SUPERFAMILY SSF88659 132 190 9.72E-11 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS36255 94c2be1f1070cf64163b9b5604b9e7b0 333 Gene3D G3DSA:1.10.1740.10 6 83 4.1E-23 T 29-03-2018 SMALA_RS36255 94c2be1f1070cf64163b9b5604b9e7b0 333 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 18 189 2.0E-25 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS36255 94c2be1f1070cf64163b9b5604b9e7b0 333 SUPERFAMILY SSF54427 203 319 1.7E-21 T 29-03-2018 IPR032710 NTF2-like domain SMALA_RS36255 94c2be1f1070cf64163b9b5604b9e7b0 333 SUPERFAMILY SSF88946 16 92 5.1E-23 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS36255 94c2be1f1070cf64163b9b5604b9e7b0 333 Pfam PF08281 Sigma-70, region 4 136 189 8.2E-14 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS36255 94c2be1f1070cf64163b9b5604b9e7b0 333 Pfam PF12680 SnoaL-like domain 212 306 1.7E-7 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain SMALA_RS36255 94c2be1f1070cf64163b9b5604b9e7b0 333 TIGRFAM TIGR02960 SigX5: RNA polymerase sigma-70 factor, TIGR02960 family 13 323 1.1E-130 T 29-03-2018 IPR014305 RNA polymerase sigma-G type, actinobacteria SMALA_RS02110 829bbdd892402084da9cffa229b73689 289 Gene3D G3DSA:1.10.260.40 1 86 2.9E-17 T 29-03-2018 SMALA_RS02110 829bbdd892402084da9cffa229b73689 289 SMART SM00530 9 81 6.0E-11 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS02110 829bbdd892402084da9cffa229b73689 289 Pfam PF13560 Helix-turn-helix domain 5 84 1.0E-17 T 29-03-2018 SMALA_RS02110 829bbdd892402084da9cffa229b73689 289 SUPERFAMILY SSF47413 29 80 1.24E-9 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS24510 624cceed2039977b9c9ad2159240d573 137 Pfam PF01042 Endoribonuclease L-PSP 17 135 8.5E-26 T 29-03-2018 IPR006175 YjgF/YER057c/UK114 family SMALA_RS24510 624cceed2039977b9c9ad2159240d573 137 Gene3D G3DSA:3.30.1330.40 4 137 6.5E-32 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SMALA_RS24510 624cceed2039977b9c9ad2159240d573 137 SUPERFAMILY SSF55298 4 137 2.04E-31 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SMALA_RS22155 0fc5242a35946069142344fd65437413 99 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 6 93 7.7E-23 T 29-03-2018 SMALA_RS22155 0fc5242a35946069142344fd65437413 99 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 1 99 19.441 T 29-03-2018 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 SMALA_RS38910 88df7e189770d86c7b54af3ef6ac4289 818 SMART SM00091 125 191 3.6 T 29-03-2018 IPR000014 PAS domain SMALA_RS38910 88df7e189770d86c7b54af3ef6ac4289 818 SMART SM00091 10 76 0.026 T 29-03-2018 IPR000014 PAS domain SMALA_RS38910 88df7e189770d86c7b54af3ef6ac4289 818 Gene3D G3DSA:3.30.450.20 132 237 1.8E-10 T 29-03-2018 SMALA_RS38910 88df7e189770d86c7b54af3ef6ac4289 818 SUPERFAMILY SSF55785 17 101 7.15E-10 T 29-03-2018 IPR000014 PAS domain SMALA_RS38910 88df7e189770d86c7b54af3ef6ac4289 818 Pfam PF00989 PAS fold 16 105 5.4E-7 T 29-03-2018 IPR013767 PAS fold GO:0006355 SMALA_RS38910 88df7e189770d86c7b54af3ef6ac4289 818 SUPERFAMILY SSF55785 123 233 5.52E-10 T 29-03-2018 IPR000014 PAS domain SMALA_RS38910 88df7e189770d86c7b54af3ef6ac4289 818 SUPERFAMILY SSF81606 478 682 6.54E-6 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS38910 88df7e189770d86c7b54af3ef6ac4289 818 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 17 101 2.1E-9 T 29-03-2018 IPR000014 PAS domain SMALA_RS38910 88df7e189770d86c7b54af3ef6ac4289 818 SUPERFAMILY SSF55874 728 804 2.41E-5 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS38910 88df7e189770d86c7b54af3ef6ac4289 818 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 490 683 3.1E-48 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS38910 88df7e189770d86c7b54af3ef6ac4289 818 Gene3D G3DSA:3.30.450.40 239 434 1.1E-28 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS38910 88df7e189770d86c7b54af3ef6ac4289 818 Gene3D G3DSA:3.30.565.10 687 812 1.1E-11 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS38910 88df7e189770d86c7b54af3ef6ac4289 818 Pfam PF01590 GAF domain 337 432 1.2E-7 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS38910 88df7e189770d86c7b54af3ef6ac4289 818 Pfam PF08448 PAS fold 131 237 4.2E-15 T 29-03-2018 IPR013656 PAS fold-4 SMALA_RS38910 88df7e189770d86c7b54af3ef6ac4289 818 SMART SM00065 245 442 0.002 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS38910 88df7e189770d86c7b54af3ef6ac4289 818 Pfam PF13581 Histidine kinase-like ATPase domain 697 791 8.7E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS38910 88df7e189770d86c7b54af3ef6ac4289 818 SUPERFAMILY SSF55781 335 443 7.63E-13 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS38910 88df7e189770d86c7b54af3ef6ac4289 818 Gene3D G3DSA:3.30.450.20 20 113 1.7E-10 T 29-03-2018 SMALA_RS38910 88df7e189770d86c7b54af3ef6ac4289 818 Gene3D G3DSA:3.60.40.10 435 686 4.3E-41 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS38910 88df7e189770d86c7b54af3ef6ac4289 818 SMART SM00331 463 683 1.5E-33 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS23725 065d976412de671ca953f22b19320a6e 281 Gene3D G3DSA:3.40.50.1580 1 274 8.6E-45 T 29-03-2018 SMALA_RS23725 065d976412de671ca953f22b19320a6e 281 Pfam PF01048 Phosphorylase superfamily 9 251 2.9E-41 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 SMALA_RS23725 065d976412de671ca953f22b19320a6e 281 SUPERFAMILY SSF53167 8 273 2.23E-82 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 SMALA_RS23725 065d976412de671ca953f22b19320a6e 281 TIGRFAM TIGR01694 MTAP: methylthioadenosine phosphorylase 10 256 1.6E-88 T 29-03-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112 SMALA_RS23725 065d976412de671ca953f22b19320a6e 281 Hamap MF_01963 S-methyl-5'-thioadenosine phosphorylase [mtnP]. 8 276 41.122 T 29-03-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112 SMALA_RS39955 2edaa662f239e3c86b6d76616e11b5aa 337 PIRSF PIRSF035875 13 317 7.6E-50 T 29-03-2018 IPR017039 Virulence factor BrkB SMALA_RS39955 2edaa662f239e3c86b6d76616e11b5aa 337 Pfam PF03631 Virulence factor BrkB 40 299 1.7E-39 T 29-03-2018 IPR017039 Virulence factor BrkB SMALA_RS27860 d8b3c8284b806770c5a7524c77dc3875 1324 SUPERFAMILY SSF55874 597 718 9.69E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS27860 d8b3c8284b806770c5a7524c77dc3875 1324 Pfam PF00672 HAMP domain 428 495 9.8E-13 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMALA_RS27860 d8b3c8284b806770c5a7524c77dc3875 1324 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 613 719 5.5E-10 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS27860 d8b3c8284b806770c5a7524c77dc3875 1324 SMART SM00304 428 498 1.0E-5 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMALA_RS27860 d8b3c8284b806770c5a7524c77dc3875 1324 Pfam PF08376 Nitrate and nitrite sensing 146 390 4.9E-41 T 29-03-2018 IPR013587 Nitrate/nitrite sensing protein SMALA_RS27860 d8b3c8284b806770c5a7524c77dc3875 1324 Gene3D G3DSA:3.30.565.10 531 720 3.6E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS38220 6b7680749caa626a3da313050028767b 591 Pfam PF00501 AMP-binding enzyme 15 460 5.9E-86 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS38220 6b7680749caa626a3da313050028767b 591 SUPERFAMILY SSF56801 9 566 9.68E-105 T 29-03-2018 SMALA_RS38220 6b7680749caa626a3da313050028767b 591 Gene3D G3DSA:3.40.50.980 5 176 4.3E-37 T 29-03-2018 SMALA_RS38220 6b7680749caa626a3da313050028767b 591 Gene3D G3DSA:3.30.300.30 453 563 8.6E-12 T 29-03-2018 SMALA_RS38220 6b7680749caa626a3da313050028767b 591 ProSitePatterns PS00455 Putative AMP-binding domain signature. 171 182 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS38220 6b7680749caa626a3da313050028767b 591 Gene3D G3DSA:2.30.38.10 372 452 1.5E-19 T 29-03-2018 SMALA_RS38220 6b7680749caa626a3da313050028767b 591 Gene3D G3DSA:3.40.50.980 177 349 2.0E-33 T 29-03-2018 SMALA_RS35510 d0d3a22edec590b7fe8641d81edf7e91 220 Pfam PF00156 Phosphoribosyl transferase domain 11 193 6.8E-19 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 SMALA_RS35510 d0d3a22edec590b7fe8641d81edf7e91 220 SUPERFAMILY SSF53271 1 208 1.31E-49 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like SMALA_RS35510 d0d3a22edec590b7fe8641d81edf7e91 220 Gene3D G3DSA:3.40.50.2020 1 211 2.5E-38 T 29-03-2018 SMALA_RS00230 0c127130287cbd036d24db43b21f31f2 342 Gene3D G3DSA:3.40.50.720 1 189 1.6E-28 T 29-03-2018 SMALA_RS00230 0c127130287cbd036d24db43b21f31f2 342 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 208 1.2E-20 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 SMALA_RS00230 0c127130287cbd036d24db43b21f31f2 342 Gene3D G3DSA:3.90.25.10 190 297 9.7E-35 T 29-03-2018 SMALA_RS00230 0c127130287cbd036d24db43b21f31f2 342 SUPERFAMILY SSF51735 1 330 9.52E-43 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS21865 3a18fe10bb1120edc1b70a0c948de40c 595 Gene3D G3DSA:1.10.730.10 459 595 1.6E-38 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMALA_RS21865 3a18fe10bb1120edc1b70a0c948de40c 595 SUPERFAMILY SSF55190 8 106 4.84E-14 T 29-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 SMALA_RS21865 3a18fe10bb1120edc1b70a0c948de40c 595 SMART SM01016 9 96 1.7E-22 T 29-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 SMALA_RS21865 3a18fe10bb1120edc1b70a0c948de40c 595 SUPERFAMILY SSF52374 120 470 3.68E-85 T 29-03-2018 SMALA_RS21865 3a18fe10bb1120edc1b70a0c948de40c 595 Pfam PF00750 tRNA synthetases class I (R) 118 463 1.5E-103 T 29-03-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 SMALA_RS21865 3a18fe10bb1120edc1b70a0c948de40c 595 PRINTS PR01038 Arginyl-tRNA synthetase signature 319 340 2.9E-24 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 SMALA_RS21865 3a18fe10bb1120edc1b70a0c948de40c 595 PRINTS PR01038 Arginyl-tRNA synthetase signature 163 176 2.9E-24 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 SMALA_RS21865 3a18fe10bb1120edc1b70a0c948de40c 595 PRINTS PR01038 Arginyl-tRNA synthetase signature 139 155 2.9E-24 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 SMALA_RS21865 3a18fe10bb1120edc1b70a0c948de40c 595 PRINTS PR01038 Arginyl-tRNA synthetase signature 124 139 2.9E-24 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 SMALA_RS21865 3a18fe10bb1120edc1b70a0c948de40c 595 SMART SM00836 478 595 2.8E-37 T 29-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 SMALA_RS21865 3a18fe10bb1120edc1b70a0c948de40c 595 SUPERFAMILY SSF47323 472 595 2.75E-31 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMALA_RS21865 3a18fe10bb1120edc1b70a0c948de40c 595 Gene3D G3DSA:3.30.1360.70 2 115 1.2E-23 T 29-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 SMALA_RS21865 3a18fe10bb1120edc1b70a0c948de40c 595 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 132 143 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMALA_RS21865 3a18fe10bb1120edc1b70a0c948de40c 595 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 13 595 1.3E-132 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 SMALA_RS21865 3a18fe10bb1120edc1b70a0c948de40c 595 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 11 96 9.6E-15 T 29-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 SMALA_RS21865 3a18fe10bb1120edc1b70a0c948de40c 595 Gene3D G3DSA:3.40.50.620 116 458 3.5E-51 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS21865 3a18fe10bb1120edc1b70a0c948de40c 595 Pfam PF05746 DALR anticodon binding domain 478 595 4.4E-30 T 29-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 SMALA_RS21865 3a18fe10bb1120edc1b70a0c948de40c 595 Hamap MF_00123 Arginine--tRNA ligase [argS]. 9 595 26.188 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 SMALA_RS40540 c7538224671ba5bd0040d9990df77a68 341 Gene3D G3DSA:3.40.190.10 139 333 2.4E-20 T 29-03-2018 SMALA_RS40540 c7538224671ba5bd0040d9990df77a68 341 Pfam PF09084 NMT1/THI5 like 42 254 1.4E-43 T 29-03-2018 IPR015168 SsuA/THI5-like SMALA_RS40540 c7538224671ba5bd0040d9990df77a68 341 Gene3D G3DSA:3.40.190.10 33 138 1.1E-12 T 29-03-2018 SMALA_RS40540 c7538224671ba5bd0040d9990df77a68 341 SUPERFAMILY SSF53850 36 256 1.27E-34 T 29-03-2018 SMALA_RS20060 00d2ae90bd4fdc7decabcc6ccb84fa55 431 SUPERFAMILY SSF103473 10 417 1.57E-53 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS20060 00d2ae90bd4fdc7decabcc6ccb84fa55 431 Gene3D G3DSA:1.20.1250.20 211 423 2.9E-15 T 29-03-2018 SMALA_RS20060 00d2ae90bd4fdc7decabcc6ccb84fa55 431 Gene3D G3DSA:1.20.1250.20 13 199 1.5E-25 T 29-03-2018 SMALA_RS20060 00d2ae90bd4fdc7decabcc6ccb84fa55 431 Pfam PF07690 Major Facilitator Superfamily 26 368 3.5E-30 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS17225 567149535bab7509376eb4bc3ad63931 532 Gene3D G3DSA:3.90.226.10 10 267 3.3E-60 T 29-03-2018 SMALA_RS17225 567149535bab7509376eb4bc3ad63931 532 SUPERFAMILY SSF52096 232 512 6.63E-75 T 29-03-2018 IPR029045 ClpP/crotonase-like domain SMALA_RS17225 567149535bab7509376eb4bc3ad63931 532 SUPERFAMILY SSF52096 23 264 4.54E-64 T 29-03-2018 IPR029045 ClpP/crotonase-like domain SMALA_RS17225 567149535bab7509376eb4bc3ad63931 532 Gene3D G3DSA:3.90.226.10 268 524 1.9E-58 T 29-03-2018 SMALA_RS17225 567149535bab7509376eb4bc3ad63931 532 Pfam PF01039 Carboxyl transferase domain 48 520 6.6E-136 T 29-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 SMALA_RS31310 f6451d329402022950959ae12c2d8855 612 SUPERFAMILY SSF52833 47 162 2.12E-26 T 29-03-2018 IPR012336 Thioredoxin-like fold SMALA_RS31310 f6451d329402022950959ae12c2d8855 612 SMART SM00928 528 575 6.6E-17 T 29-03-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS31310 f6451d329402022950959ae12c2d8855 612 Gene3D G3DSA:3.10.560.10 432 589 3.0E-5 T 29-03-2018 SMALA_RS31310 f6451d329402022950959ae12c2d8855 612 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 50 160 2.1E-23 T 29-03-2018 SMALA_RS31310 f6451d329402022950959ae12c2d8855 612 SUPERFAMILY SSF140490 526 606 4.32E-22 T 29-03-2018 SMALA_RS31310 f6451d329402022950959ae12c2d8855 612 Gene3D G3DSA:3.40.30.10 105 186 8.5E-6 T 29-03-2018 SMALA_RS31310 f6451d329402022950959ae12c2d8855 612 SUPERFAMILY SSF142984 444 523 1.31E-19 T 29-03-2018 SMALA_RS31310 f6451d329402022950959ae12c2d8855 612 Pfam PF10531 SLBB domain 446 476 1.4E-8 T 29-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS31310 f6451d329402022950959ae12c2d8855 612 SUPERFAMILY SSF142019 212 443 2.62E-86 T 29-03-2018 SMALA_RS31310 f6451d329402022950959ae12c2d8855 612 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 541 552 - T 29-03-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS31310 f6451d329402022950959ae12c2d8855 612 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 530 606 1.3E-21 T 29-03-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS31310 f6451d329402022950959ae12c2d8855 612 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 251 421 1.3E-50 T 29-03-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS18255 ecbb01faf65c34d507e3455662a7434d 425 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 83 389 3.8E-65 T 29-03-2018 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 SMALA_RS18255 ecbb01faf65c34d507e3455662a7434d 425 SUPERFAMILY SSF51445 73 417 8.24E-91 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS18255 ecbb01faf65c34d507e3455662a7434d 425 Gene3D G3DSA:3.20.20.80 68 416 4.5E-69 T 29-03-2018 SMALA_RS18255 ecbb01faf65c34d507e3455662a7434d 425 ProSitePatterns PS00659 Glycosyl hydrolases family 5 signature. 223 232 - T 29-03-2018 IPR018087 Glycoside hydrolase, family 5, conserved site GO:0004553|GO:0005975 SMALA_RS36865 b85840db00e772f79713a68efc61dab5 664 Gene3D G3DSA:3.30.70.270 34 205 1.0E-12 T 29-03-2018 SMALA_RS36865 b85840db00e772f79713a68efc61dab5 664 SUPERFAMILY SSF55073 43 183 1.65E-6 T 29-03-2018 IPR029787 Nucleotide cyclase SMALA_RS36865 b85840db00e772f79713a68efc61dab5 664 SMART SM00267 20 197 0.0081 T 29-03-2018 IPR000160 GGDEF domain SMALA_RS36865 b85840db00e772f79713a68efc61dab5 664 Gene3D G3DSA:3.90.550.10 276 541 1.2E-36 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS36865 b85840db00e772f79713a68efc61dab5 664 Pfam PF13641 Glycosyltransferase like family 2 293 515 1.0E-27 T 29-03-2018 SMALA_RS36865 b85840db00e772f79713a68efc61dab5 664 SUPERFAMILY SSF53448 294 538 1.13E-33 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS03445 14dad083000f3f84791b4efc6d04ffbf 393 Gene3D G3DSA:3.40.190.10 186 345 6.4E-17 T 29-03-2018 SMALA_RS03445 14dad083000f3f84791b4efc6d04ffbf 393 SUPERFAMILY SSF53850 45 392 1.2E-62 T 29-03-2018 SMALA_RS03445 14dad083000f3f84791b4efc6d04ffbf 393 Gene3D G3DSA:3.40.190.10 9 185 1.8E-20 T 29-03-2018 SMALA_RS03445 14dad083000f3f84791b4efc6d04ffbf 393 Pfam PF13416 Bacterial extracellular solute-binding protein 68 337 2.8E-28 T 29-03-2018 SMALA_RS01505 e34c5deaf751e8512158fceb9b6d8ea3 407 PRINTS PR00359 B-class P450 signature 102 113 1.1E-54 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS01505 e34c5deaf751e8512158fceb9b6d8ea3 407 PRINTS PR00359 B-class P450 signature 149 165 1.1E-54 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS01505 e34c5deaf751e8512158fceb9b6d8ea3 407 PRINTS PR00359 B-class P450 signature 166 181 1.1E-54 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS01505 e34c5deaf751e8512158fceb9b6d8ea3 407 PRINTS PR00359 B-class P450 signature 203 225 1.1E-54 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS01505 e34c5deaf751e8512158fceb9b6d8ea3 407 PRINTS PR00359 B-class P450 signature 280 291 1.1E-54 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS01505 e34c5deaf751e8512158fceb9b6d8ea3 407 PRINTS PR00359 B-class P450 signature 326 341 1.1E-54 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS01505 e34c5deaf751e8512158fceb9b6d8ea3 407 PRINTS PR00359 B-class P450 signature 347 356 1.1E-54 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS01505 e34c5deaf751e8512158fceb9b6d8ea3 407 PRINTS PR00359 B-class P450 signature 356 367 1.1E-54 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS01505 e34c5deaf751e8512158fceb9b6d8ea3 407 PRINTS PR00359 B-class P450 signature 298 325 1.1E-54 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS01505 e34c5deaf751e8512158fceb9b6d8ea3 407 PRINTS PR00385 P450 superfamily signature 356 367 5.7E-8 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS01505 e34c5deaf751e8512158fceb9b6d8ea3 407 PRINTS PR00385 P450 superfamily signature 280 291 5.7E-8 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS01505 e34c5deaf751e8512158fceb9b6d8ea3 407 PRINTS PR00385 P450 superfamily signature 245 262 5.7E-8 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS01505 e34c5deaf751e8512158fceb9b6d8ea3 407 PRINTS PR00385 P450 superfamily signature 347 356 5.7E-8 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS01505 e34c5deaf751e8512158fceb9b6d8ea3 407 Gene3D G3DSA:1.10.630.10 8 407 1.3E-73 T 29-03-2018 SMALA_RS01505 e34c5deaf751e8512158fceb9b6d8ea3 407 SUPERFAMILY SSF48264 35 407 7.47E-91 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS01505 e34c5deaf751e8512158fceb9b6d8ea3 407 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 349 358 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMALA_RS01505 e34c5deaf751e8512158fceb9b6d8ea3 407 Pfam PF00067 Cytochrome P450 215 377 1.9E-21 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS12025 b2f7cd174152960ce6e09dbd285a43f2 330 Gene3D G3DSA:3.40.366.10 193 313 1.1E-28 T 29-03-2018 SMALA_RS12025 b2f7cd174152960ce6e09dbd285a43f2 330 Gene3D G3DSA:3.40.366.10 1 145 2.0E-24 T 29-03-2018 SMALA_RS12025 b2f7cd174152960ce6e09dbd285a43f2 330 Gene3D G3DSA:3.30.70.250 146 192 2.2E-15 T 29-03-2018 SMALA_RS12025 b2f7cd174152960ce6e09dbd285a43f2 330 SUPERFAMILY SSF52151 2 128 2.38E-64 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS12025 b2f7cd174152960ce6e09dbd285a43f2 330 SUPERFAMILY SSF52151 191 313 2.38E-64 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS12025 b2f7cd174152960ce6e09dbd285a43f2 330 Pfam PF00698 Acyl transferase domain 35 291 1.1E-18 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS12025 b2f7cd174152960ce6e09dbd285a43f2 330 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 5 323 1.9E-17 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS12025 b2f7cd174152960ce6e09dbd285a43f2 330 SUPERFAMILY SSF55048 136 191 1.19E-11 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS36990 a35abc6508c3b0b61574843c8a1d9e4a 405 SUPERFAMILY SSF54826 10 113 1.84E-31 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMALA_RS36990 a35abc6508c3b0b61574843c8a1d9e4a 405 Gene3D G3DSA:3.20.20.120 102 378 2.9E-63 T 29-03-2018 IPR029065 Enolase C-terminal domain-like SMALA_RS36990 a35abc6508c3b0b61574843c8a1d9e4a 405 SMART SM00922 130 260 3.9E-17 T 29-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal SMALA_RS36990 a35abc6508c3b0b61574843c8a1d9e4a 405 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 210 241 - T 29-03-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 SMALA_RS36990 a35abc6508c3b0b61574843c8a1d9e4a 405 Gene3D G3DSA:3.30.390.10 6 101 1.4E-30 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMALA_RS36990 a35abc6508c3b0b61574843c8a1d9e4a 405 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 86 111 - T 29-03-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 SMALA_RS36990 a35abc6508c3b0b61574843c8a1d9e4a 405 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 15 111 1.8E-32 T 29-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain SMALA_RS36990 a35abc6508c3b0b61574843c8a1d9e4a 405 SUPERFAMILY SSF51604 99 389 1.83E-75 T 29-03-2018 IPR029065 Enolase C-terminal domain-like SMALA_RS36990 a35abc6508c3b0b61574843c8a1d9e4a 405 Pfam PF13378 Enolase C-terminal domain-like 193 380 1.4E-46 T 29-03-2018 IPR029065 Enolase C-terminal domain-like SMALA_RS28485 51f7c78a52e652d4faf0d8f9e1e82f47 156 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 2 116 19.519 T 29-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 SMALA_RS28485 51f7c78a52e652d4faf0d8f9e1e82f47 156 Pfam PF02033 Ribosome-binding factor A 6 109 1.6E-25 T 29-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 SMALA_RS28485 51f7c78a52e652d4faf0d8f9e1e82f47 156 SUPERFAMILY SSF89919 2 112 6.02E-31 T 29-03-2018 IPR023799 Ribosome-binding factor A domain SMALA_RS28485 51f7c78a52e652d4faf0d8f9e1e82f47 156 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 9 96 9.0E-26 T 29-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 SMALA_RS28485 51f7c78a52e652d4faf0d8f9e1e82f47 156 Gene3D G3DSA:3.30.300.20 4 116 1.9E-29 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta SMALA_RS28485 51f7c78a52e652d4faf0d8f9e1e82f47 156 ProSitePatterns PS01319 Ribosome-binding factor A signature. 75 96 - T 29-03-2018 IPR020053 Ribosome-binding factor A, conserved site GO:0006364 SMALA_RS28485 51f7c78a52e652d4faf0d8f9e1e82f47 156 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 1 110 7.6E-22 T 29-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 SMALA_RS30140 72bd6ff825a29b787319b928d27f6394 142 Gene3D G3DSA:3.30.565.10 11 142 1.1E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS30140 72bd6ff825a29b787319b928d27f6394 142 SUPERFAMILY SSF55874 42 134 1.31E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS30140 72bd6ff825a29b787319b928d27f6394 142 Pfam PF13581 Histidine kinase-like ATPase domain 22 114 5.5E-7 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS11100 f1fe2d7cc636e5c7ae13601401280227 483 Pfam PF04213 Htaa 248 396 2.5E-40 T 29-03-2018 IPR007331 Htaa SMALA_RS11100 f1fe2d7cc636e5c7ae13601401280227 483 Pfam PF04213 Htaa 48 216 3.8E-49 T 29-03-2018 IPR007331 Htaa SMALA_RS06380 9be43e77a93d1825bf73d22d82d95769 325 Gene3D G3DSA:2.60.40.10 26 163 2.9E-9 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS06380 9be43e77a93d1825bf73d22d82d95769 325 Gene3D G3DSA:2.60.40.10 171 278 2.6E-4 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS05740 4e183a54266a68f6a661b83a87956f35 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 63 6.3E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS05740 4e183a54266a68f6a661b83a87956f35 192 SUPERFAMILY SSF48498 84 187 6.5E-10 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS05740 4e183a54266a68f6a661b83a87956f35 192 SUPERFAMILY SSF46689 5 83 4.04E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS05740 4e183a54266a68f6a661b83a87956f35 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 6.2E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS05740 4e183a54266a68f6a661b83a87956f35 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 6.2E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS05740 4e183a54266a68f6a661b83a87956f35 192 Gene3D G3DSA:1.10.357.10 2 191 2.5E-32 T 29-03-2018 SMALA_RS28940 6f719cb645130e252bc093c42ba4f15b 526 Gene3D G3DSA:3.90.1150.10 15 179 2.5E-33 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS28940 6f719cb645130e252bc093c42ba4f15b 526 PIRSF PIRSF000521 448 499 1.7 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMALA_RS28940 6f719cb645130e252bc093c42ba4f15b 526 PIRSF PIRSF000521 137 387 8.5E-29 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMALA_RS28940 6f719cb645130e252bc093c42ba4f15b 526 PIRSF PIRSF000521 39 143 0.0033 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMALA_RS28940 6f719cb645130e252bc093c42ba4f15b 526 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 259 296 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMALA_RS28940 6f719cb645130e252bc093c42ba4f15b 526 Gene3D G3DSA:3.40.640.10 201 327 8.3E-37 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS28940 6f719cb645130e252bc093c42ba4f15b 526 TIGRFAM TIGR00709 dat: 2,4-diaminobutyrate 4-transaminase 16 385 2.0E-127 T 29-03-2018 IPR004637 2,4-diaminobutyrate 4-transaminase GO:0008483|GO:0009058 KEGG: 00260+2.6.1.76|MetaCyc: PWY-6409|MetaCyc: PWY-6562|MetaCyc: PWY-761|MetaCyc: PWY-7855 SMALA_RS28940 6f719cb645130e252bc093c42ba4f15b 526 Pfam PF00202 Aminotransferase class-III 33 496 4.0E-89 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMALA_RS28940 6f719cb645130e252bc093c42ba4f15b 526 SUPERFAMILY SSF53383 26 391 4.61E-101 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS28940 6f719cb645130e252bc093c42ba4f15b 526 SUPERFAMILY SSF53383 454 497 4.61E-101 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS28940 6f719cb645130e252bc093c42ba4f15b 526 Gene3D G3DSA:3.90.1150.10 328 509 1.2E-40 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS27945 feb2704ab755f5ac78c017fba87672b1 252 SMART SM00563 41 159 4.6E-33 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SMALA_RS27945 feb2704ab755f5ac78c017fba87672b1 252 SUPERFAMILY SSF69593 5 224 4.45E-39 T 29-03-2018 SMALA_RS27945 feb2704ab755f5ac78c017fba87672b1 252 Gene3D G3DSA:3.40.1130.10 8 233 5.3E-46 T 29-03-2018 SMALA_RS27945 feb2704ab755f5ac78c017fba87672b1 252 Pfam PF01553 Acyltransferase 29 155 1.5E-23 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SMALA_RS09545 4785a63529b432dd8a2176d5f97d2161 260 SUPERFAMILY SSF100950 6 253 4.14E-63 T 29-03-2018 SMALA_RS09545 4785a63529b432dd8a2176d5f97d2161 260 TIGRFAM TIGR01198 pgl: 6-phosphogluconolactonase 8 248 4.9E-79 T 29-03-2018 IPR005900 6-phosphogluconolactonase, DevB-type GO:0005975|GO:0006098|GO:0017057 KEGG: 00030+3.1.1.31 SMALA_RS09545 4785a63529b432dd8a2176d5f97d2161 260 Gene3D G3DSA:3.40.50.1360 1 257 1.4E-78 T 29-03-2018 SMALA_RS09545 4785a63529b432dd8a2176d5f97d2161 260 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 11 240 2.1E-72 T 29-03-2018 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 SMALA_RS11170 1887cba610aca610ac197cf946ddf860 446 Gene3D G3DSA:1.20.1250.20 38 234 7.6E-30 T 29-03-2018 SMALA_RS11170 1887cba610aca610ac197cf946ddf860 446 Gene3D G3DSA:1.20.1250.20 237 444 5.9E-15 T 29-03-2018 SMALA_RS11170 1887cba610aca610ac197cf946ddf860 446 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 47 431 2.7E-100 T 29-03-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 SMALA_RS11170 1887cba610aca610ac197cf946ddf860 446 ProSitePatterns PS00216 Sugar transport proteins signature 1. 102 118 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMALA_RS11170 1887cba610aca610ac197cf946ddf860 446 Pfam PF07690 Major Facilitator Superfamily 57 398 2.2E-41 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS11170 1887cba610aca610ac197cf946ddf860 446 PRINTS PR01035 Tetracycline resistance protein signature 58 74 1.1E-5 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 SMALA_RS11170 1887cba610aca610ac197cf946ddf860 446 PRINTS PR01035 Tetracycline resistance protein signature 115 139 1.1E-5 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 SMALA_RS11170 1887cba610aca610ac197cf946ddf860 446 PRINTS PR01035 Tetracycline resistance protein signature 142 163 1.1E-5 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 SMALA_RS11170 1887cba610aca610ac197cf946ddf860 446 PRINTS PR01035 Tetracycline resistance protein signature 328 348 1.1E-5 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 SMALA_RS11170 1887cba610aca610ac197cf946ddf860 446 SUPERFAMILY SSF103473 39 438 2.22E-62 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS42265 75804864eedfa524636377c4da932fbb 491 PRINTS PR00415 Aconitase family signature 133 148 3.4E-42 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS42265 75804864eedfa524636377c4da932fbb 491 PRINTS PR00415 Aconitase family signature 108 116 3.4E-42 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS42265 75804864eedfa524636377c4da932fbb 491 PRINTS PR00415 Aconitase family signature 82 95 3.4E-42 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS42265 75804864eedfa524636377c4da932fbb 491 PRINTS PR00415 Aconitase family signature 195 208 3.4E-42 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS42265 75804864eedfa524636377c4da932fbb 491 PRINTS PR00415 Aconitase family signature 400 413 3.4E-42 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS42265 75804864eedfa524636377c4da932fbb 491 PRINTS PR00415 Aconitase family signature 119 132 3.4E-42 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS42265 75804864eedfa524636377c4da932fbb 491 PRINTS PR00415 Aconitase family signature 342 353 3.4E-42 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS42265 75804864eedfa524636377c4da932fbb 491 PRINTS PR00415 Aconitase family signature 286 300 3.4E-42 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS42265 75804864eedfa524636377c4da932fbb 491 PRINTS PR00415 Aconitase family signature 209 222 3.4E-42 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS42265 75804864eedfa524636377c4da932fbb 491 Pfam PF00330 Aconitase family (aconitate hydratase) 7 459 2.0E-135 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS42265 75804864eedfa524636377c4da932fbb 491 SUPERFAMILY SSF53732 2 467 6.8E-143 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS42265 75804864eedfa524636377c4da932fbb 491 Gene3D G3DSA:3.40.1060.10 155 288 3.4E-36 T 29-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS42265 75804864eedfa524636377c4da932fbb 491 Gene3D G3DSA:3.30.499.10 312 476 2.2E-41 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS42265 75804864eedfa524636377c4da932fbb 491 Gene3D G3DSA:3.30.499.10 1 154 3.8E-32 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS28850 a1d8f5a819fa95b96ac7823e8f55a0c8 303 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 88 101 - T 29-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 SMALA_RS28850 a1d8f5a819fa95b96ac7823e8f55a0c8 303 SMART SM00062 65 289 3.6E-48 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SMALA_RS28850 a1d8f5a819fa95b96ac7823e8f55a0c8 303 Gene3D G3DSA:3.40.190.10 169 251 9.4E-20 T 29-03-2018 SMALA_RS28850 a1d8f5a819fa95b96ac7823e8f55a0c8 303 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 66 283 2.0E-45 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SMALA_RS28850 a1d8f5a819fa95b96ac7823e8f55a0c8 303 Gene3D G3DSA:3.40.190.10 55 168 1.2E-24 T 29-03-2018 SMALA_RS28850 a1d8f5a819fa95b96ac7823e8f55a0c8 303 SUPERFAMILY SSF53850 55 283 3.63E-54 T 29-03-2018 SMALA_RS28850 a1d8f5a819fa95b96ac7823e8f55a0c8 303 SUPERFAMILY SSF53850 7 24 3.63E-54 T 29-03-2018 SMALA_RS30055 3c23e1b7e6ebf77316a4cd6606090fd2 266 Gene3D G3DSA:3.10.450.40 74 164 7.3E-14 T 29-03-2018 SMALA_RS30055 3c23e1b7e6ebf77316a4cd6606090fd2 266 SUPERFAMILY SSF54416 75 165 7.85E-5 T 29-03-2018 IPR016182 Copper amine oxidase, N-terminal GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 SMALA_RS05480 f01bdc9e60ec6c2e1d4e621fe9f82d1b 188 Pfam PF10400 Virulence activator alpha C-term 92 180 1.7E-19 T 29-03-2018 IPR018309 Transcription regulator PadR, C-terminal SMALA_RS05480 f01bdc9e60ec6c2e1d4e621fe9f82d1b 188 Gene3D G3DSA:1.10.10.10 1 88 3.4E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS05480 f01bdc9e60ec6c2e1d4e621fe9f82d1b 188 Pfam PF03551 Transcriptional regulator PadR-like family 7 81 6.8E-13 T 29-03-2018 IPR005149 Transcription regulator PadR, N-terminal SMALA_RS05480 f01bdc9e60ec6c2e1d4e621fe9f82d1b 188 SUPERFAMILY SSF46785 3 181 2.94E-37 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS28165 3a0058a8e09178dc4c2b3135fb50f9a2 394 SUPERFAMILY SSF51306 154 259 1.05E-48 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C SMALA_RS28165 3a0058a8e09178dc4c2b3135fb50f9a2 394 SUPERFAMILY SSF51306 73 121 1.05E-48 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C SMALA_RS28165 3a0058a8e09178dc4c2b3135fb50f9a2 394 ProSitePatterns PS00761 Signal peptidases I signature 3. 212 225 - T 29-03-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 SMALA_RS28165 3a0058a8e09178dc4c2b3135fb50f9a2 394 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 61 253 3.8E-40 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SMALA_RS28165 3a0058a8e09178dc4c2b3135fb50f9a2 394 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 207 226 2.8E-20 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SMALA_RS28165 3a0058a8e09178dc4c2b3135fb50f9a2 394 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 74 90 2.8E-20 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SMALA_RS28165 3a0058a8e09178dc4c2b3135fb50f9a2 394 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 159 171 2.8E-20 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SMALA_RS28165 3a0058a8e09178dc4c2b3135fb50f9a2 394 Pfam PF00717 Peptidase S24-like 81 123 7.8E-13 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C SMALA_RS28165 3a0058a8e09178dc4c2b3135fb50f9a2 394 Pfam PF10502 Signal peptidase, peptidase S26 158 248 1.3E-9 T 29-03-2018 IPR019533 Peptidase S26 SMALA_RS28165 3a0058a8e09178dc4c2b3135fb50f9a2 394 Gene3D G3DSA:2.10.109.10 70 267 1.6E-47 T 29-03-2018 SMALA_RS05650 e18bcff52f8d0363016201943da576a3 455 ProSitePatterns PS00217 Sugar transport proteins signature 2. 135 160 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMALA_RS05650 e18bcff52f8d0363016201943da576a3 455 Pfam PF07690 Major Facilitator Superfamily 265 431 1.8E-9 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS05650 e18bcff52f8d0363016201943da576a3 455 Pfam PF00083 Sugar (and other) transporter 30 239 6.7E-23 T 29-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 SMALA_RS05650 e18bcff52f8d0363016201943da576a3 455 Gene3D G3DSA:1.20.1250.20 233 451 1.4E-23 T 29-03-2018 SMALA_RS05650 e18bcff52f8d0363016201943da576a3 455 SUPERFAMILY SSF103473 19 434 2.88E-64 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS05650 e18bcff52f8d0363016201943da576a3 455 Gene3D G3DSA:1.20.1250.20 20 232 5.6E-24 T 29-03-2018 SMALA_RS34480 0eb7f010d3868b6dd927046df51bc7bb 435 TIGRFAM TIGR03814 Gln_ase: glutaminase A 18 306 4.5E-101 T 29-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 SMALA_RS34480 0eb7f010d3868b6dd927046df51bc7bb 435 Gene3D G3DSA:3.30.750.24 318 428 1.9E-6 T 29-03-2018 IPR002645 STAS domain SMALA_RS34480 0eb7f010d3868b6dd927046df51bc7bb 435 Pfam PF04960 Glutaminase 22 306 1.7E-113 T 29-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 SMALA_RS34480 0eb7f010d3868b6dd927046df51bc7bb 435 SUPERFAMILY SSF56601 6 307 4.96E-108 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMALA_RS34480 0eb7f010d3868b6dd927046df51bc7bb 435 Gene3D G3DSA:3.40.710.10 1 309 6.0E-123 T 29-03-2018 SMALA_RS34480 0eb7f010d3868b6dd927046df51bc7bb 435 Hamap MF_00313 Glutaminase [glsA]. 5 307 40.106 T 29-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 SMALA_RS34480 0eb7f010d3868b6dd927046df51bc7bb 435 SUPERFAMILY SSF52091 330 399 8.04E-6 T 29-03-2018 IPR002645 STAS domain SMALA_RS19430 8a4c4c301608d1b08fe68729bb6be7a5 366 Pfam PF13377 Periplasmic binding protein-like domain 189 348 2.3E-29 T 29-03-2018 SMALA_RS19430 8a4c4c301608d1b08fe68729bb6be7a5 366 Gene3D G3DSA:3.40.50.2300 76 185 4.0E-17 T 29-03-2018 SMALA_RS19430 8a4c4c301608d1b08fe68729bb6be7a5 366 ProSitePatterns PS00356 LacI-type HTH domain signature. 22 40 - T 29-03-2018 SMALA_RS19430 8a4c4c301608d1b08fe68729bb6be7a5 366 Gene3D G3DSA:1.10.260.40 21 75 4.7E-23 T 29-03-2018 SMALA_RS19430 8a4c4c301608d1b08fe68729bb6be7a5 366 SMART SM00354 19 89 4.6E-21 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS19430 8a4c4c301608d1b08fe68729bb6be7a5 366 SUPERFAMILY SSF53822 98 353 1.47E-36 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SMALA_RS19430 8a4c4c301608d1b08fe68729bb6be7a5 366 Pfam PF00356 Bacterial regulatory proteins, lacI family 22 66 4.2E-14 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS19430 8a4c4c301608d1b08fe68729bb6be7a5 366 SUPERFAMILY SSF47413 19 77 9.85E-17 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS19430 8a4c4c301608d1b08fe68729bb6be7a5 366 Gene3D G3DSA:3.40.50.2300 186 351 3.6E-35 T 29-03-2018 SMALA_RS27650 ce1d361ab511d036ff42fcfc87b9ef9d 703 Gene3D G3DSA:3.20.20.450 418 669 2.6E-94 T 29-03-2018 IPR001633 EAL domain SMALA_RS27650 ce1d361ab511d036ff42fcfc87b9ef9d 703 SUPERFAMILY SSF141868 427 672 1.18E-82 T 29-03-2018 IPR001633 EAL domain SMALA_RS27650 ce1d361ab511d036ff42fcfc87b9ef9d 703 Pfam PF00563 EAL domain 428 659 2.7E-70 T 29-03-2018 IPR001633 EAL domain SMALA_RS27650 ce1d361ab511d036ff42fcfc87b9ef9d 703 SUPERFAMILY SSF55073 256 406 1.1E-42 T 29-03-2018 IPR029787 Nucleotide cyclase SMALA_RS27650 ce1d361ab511d036ff42fcfc87b9ef9d 703 Gene3D G3DSA:3.30.70.270 247 417 2.2E-50 T 29-03-2018 SMALA_RS27650 ce1d361ab511d036ff42fcfc87b9ef9d 703 SMART SM00267 245 411 5.8E-47 T 29-03-2018 IPR000160 GGDEF domain SMALA_RS27650 ce1d361ab511d036ff42fcfc87b9ef9d 703 SMART SM00052 421 665 1.5E-101 T 29-03-2018 IPR001633 EAL domain SMALA_RS27650 ce1d361ab511d036ff42fcfc87b9ef9d 703 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 251 405 2.2E-33 T 29-03-2018 IPR000160 GGDEF domain SMALA_RS27650 ce1d361ab511d036ff42fcfc87b9ef9d 703 Pfam PF00990 Diguanylate cyclase, GGDEF domain 253 405 1.5E-39 T 29-03-2018 IPR000160 GGDEF domain SMALA_RS22230 29bc8e43b540c0d19e01f27cc3724b23 285 Pfam PF13460 NAD(P)H-binding 7 184 1.9E-18 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS22230 29bc8e43b540c0d19e01f27cc3724b23 285 Gene3D G3DSA:3.40.50.720 1 144 1.8E-19 T 29-03-2018 SMALA_RS22230 29bc8e43b540c0d19e01f27cc3724b23 285 SUPERFAMILY SSF51735 3 254 3.1E-55 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS22230 29bc8e43b540c0d19e01f27cc3724b23 285 Gene3D G3DSA:3.90.25.10 145 284 0.0016 T 29-03-2018 SMALA_RS00815 e56fdc9217112dd39071b2767fdb04c4 230 Pfam PF00072 Response regulator receiver domain 4 114 3.6E-22 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS00815 e56fdc9217112dd39071b2767fdb04c4 230 PIRSF PIRSF006171 1 230 3.1E-76 T 29-03-2018 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0001071|GO:0003677|GO:0005737|GO:0009605 SMALA_RS00815 e56fdc9217112dd39071b2767fdb04c4 230 Pfam PF09339 IclR helix-turn-helix domain 171 206 1.5E-7 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMALA_RS00815 e56fdc9217112dd39071b2767fdb04c4 230 Gene3D G3DSA:1.10.10.10 134 228 2.8E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS00815 e56fdc9217112dd39071b2767fdb04c4 230 SUPERFAMILY SSF52172 1 127 5.69E-33 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS00815 e56fdc9217112dd39071b2767fdb04c4 230 SMART SM00448 2 115 1.3E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS00815 e56fdc9217112dd39071b2767fdb04c4 230 Gene3D G3DSA:3.40.50.2300 1 133 6.9E-30 T 29-03-2018 SMALA_RS00815 e56fdc9217112dd39071b2767fdb04c4 230 SUPERFAMILY SSF46785 168 225 3.31E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS34575 e7c5ffb9de7a501cfdba41f729156f83 110 Gene3D G3DSA:1.10.720.10 80 110 6.9E-7 T 29-03-2018 SMALA_RS09130 d7cc68c1e0cbd26d33dbc02b681c0815 628 SUPERFAMILY SSF55781 249 367 1.33E-8 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS09130 d7cc68c1e0cbd26d33dbc02b681c0815 628 SMART SM00331 389 618 5.6E-37 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS09130 d7cc68c1e0cbd26d33dbc02b681c0815 628 Gene3D G3DSA:3.60.40.10 362 618 4.7E-29 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS09130 d7cc68c1e0cbd26d33dbc02b681c0815 628 Gene3D G3DSA:3.30.565.10 8 178 4.7E-7 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS09130 d7cc68c1e0cbd26d33dbc02b681c0815 628 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 416 617 2.6E-37 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS09130 d7cc68c1e0cbd26d33dbc02b681c0815 628 Gene3D G3DSA:3.30.450.40 217 361 2.3E-17 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS10305 e592b6cff597c97371c20e11d17c8369 206 Gene3D G3DSA:1.10.357.10 60 196 3.7E-22 T 29-03-2018 SMALA_RS10305 e592b6cff597c97371c20e11d17c8369 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 2.8E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS10305 e592b6cff597c97371c20e11d17c8369 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 2.8E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS10305 e592b6cff597c97371c20e11d17c8369 206 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 61 6.4E-18 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS10305 e592b6cff597c97371c20e11d17c8369 206 Gene3D G3DSA:1.10.10.60 9 59 7.3E-21 T 29-03-2018 SMALA_RS10305 e592b6cff597c97371c20e11d17c8369 206 SUPERFAMILY SSF48498 87 195 4.71E-16 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS10305 e592b6cff597c97371c20e11d17c8369 206 SUPERFAMILY SSF46689 4 78 4.21E-20 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS29660 6661924bbb663795539430b87db0a724 269 Gene3D G3DSA:2.70.98.10 2 266 2.1E-7 T 29-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 SMALA_RS22715 f6b2b66eb034c7c4171f0b523ca507c5 410 Gene3D G3DSA:3.60.40.10 190 410 4.0E-24 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS22715 f6b2b66eb034c7c4171f0b523ca507c5 410 SMART SM00331 194 407 1.8E-21 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS22715 f6b2b66eb034c7c4171f0b523ca507c5 410 SUPERFAMILY SSF81606 211 371 8.11E-6 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS22715 f6b2b66eb034c7c4171f0b523ca507c5 410 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 223 407 1.1E-31 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS27240 ec3259e6e11e78726597c51e1fbacd98 148 Pfam PF13581 Histidine kinase-like ATPase domain 32 137 2.2E-12 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS27240 ec3259e6e11e78726597c51e1fbacd98 148 SUPERFAMILY SSF55874 47 134 6.85E-9 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS27240 ec3259e6e11e78726597c51e1fbacd98 148 Gene3D G3DSA:3.30.565.10 17 148 7.0E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS21300 092941d38c97ed84c749a329e2d7e806 335 Pfam PF01464 Transglycosylase SLT domain 65 174 1.4E-15 T 29-03-2018 IPR008258 Transglycosylase SLT domain 1 SMALA_RS21300 092941d38c97ed84c749a329e2d7e806 335 SUPERFAMILY SSF53955 46 189 6.57E-34 T 29-03-2018 IPR023346 Lysozyme-like domain SMALA_RS21300 092941d38c97ed84c749a329e2d7e806 335 Pfam PF00877 NlpC/P60 family 212 308 5.7E-23 T 29-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain SMALA_RS21300 092941d38c97ed84c749a329e2d7e806 335 Gene3D G3DSA:3.90.1720.10 192 331 6.0E-33 T 29-03-2018 SMALA_RS21300 092941d38c97ed84c749a329e2d7e806 335 Gene3D G3DSA:1.10.530.10 38 191 5.0E-37 T 29-03-2018 SMALA_RS21300 092941d38c97ed84c749a329e2d7e806 335 SUPERFAMILY SSF54001 195 321 1.13E-35 T 29-03-2018 SMALA_RS27290 7f96242e17ccedae3dc52d52ed50f55a 479 PRINTS PR00173 Glutamate-aspartate symporter signature 26 46 1.2E-26 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SMALA_RS27290 7f96242e17ccedae3dc52d52ed50f55a 479 PRINTS PR00173 Glutamate-aspartate symporter signature 208 227 1.2E-26 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SMALA_RS27290 7f96242e17ccedae3dc52d52ed50f55a 479 PRINTS PR00173 Glutamate-aspartate symporter signature 344 363 1.2E-26 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SMALA_RS27290 7f96242e17ccedae3dc52d52ed50f55a 479 PRINTS PR00173 Glutamate-aspartate symporter signature 309 335 1.2E-26 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SMALA_RS27290 7f96242e17ccedae3dc52d52ed50f55a 479 PRINTS PR00173 Glutamate-aspartate symporter signature 93 118 1.2E-26 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SMALA_RS27290 7f96242e17ccedae3dc52d52ed50f55a 479 SUPERFAMILY SSF118215 28 418 9.02E-103 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SMALA_RS27290 7f96242e17ccedae3dc52d52ed50f55a 479 Pfam PF00375 Sodium:dicarboxylate symporter family 28 417 6.9E-99 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SMALA_RS27290 7f96242e17ccedae3dc52d52ed50f55a 479 Gene3D G3DSA:1.10.3860.10 21 425 1.3E-101 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SMALA_RS27290 7f96242e17ccedae3dc52d52ed50f55a 479 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 55 70 - T 29-03-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site SMALA_RS12370 d853f9f310a00f5e0faf5a16ef7fd544 453 Gene3D G3DSA:1.10.3210.10 25 243 3.1E-64 T 29-03-2018 SMALA_RS12370 d853f9f310a00f5e0faf5a16ef7fd544 453 Gene3D G3DSA:1.10.3410.10 244 379 7.7E-30 T 29-03-2018 IPR023293 Deoxyguanosinetriphosphate triphosphohydrolase, central domain SMALA_RS12370 d853f9f310a00f5e0faf5a16ef7fd544 453 Pfam PF01966 HD domain 96 250 7.4E-16 T 29-03-2018 IPR006674 HD domain SMALA_RS12370 d853f9f310a00f5e0faf5a16ef7fd544 453 TIGRFAM TIGR01353 dGTP_triPase: putative dGTPase 46 452 2.6E-67 T 29-03-2018 IPR006261 dNTP triphosphohydrolase GO:0016793 SMALA_RS12370 d853f9f310a00f5e0faf5a16ef7fd544 453 Pfam PF13286 Phosphohydrolase-associated domain 359 450 6.3E-16 T 29-03-2018 IPR026875 Phosphohydrolase-associated domain SMALA_RS12370 d853f9f310a00f5e0faf5a16ef7fd544 453 SUPERFAMILY SSF109604 232 421 2.77E-54 T 29-03-2018 SMALA_RS12370 d853f9f310a00f5e0faf5a16ef7fd544 453 SUPERFAMILY SSF109604 40 201 2.77E-54 T 29-03-2018 SMALA_RS12370 d853f9f310a00f5e0faf5a16ef7fd544 453 SMART SM00471 92 261 6.7E-13 T 29-03-2018 IPR003607 HD/PDEase domain SMALA_RS30010 d846ccfd795bc6a22fec3d608dfdacba 277 Gene3D G3DSA:3.40.430.10 50 277 1.1E-47 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 SMALA_RS30010 d846ccfd795bc6a22fec3d608dfdacba 277 Pfam PF01872 RibD C-terminal domain 56 258 3.3E-29 T 29-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 SMALA_RS30010 d846ccfd795bc6a22fec3d608dfdacba 277 SUPERFAMILY SSF53597 56 274 4.91E-37 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 SMALA_RS39495 9e35de1531d545f31be5713646d191b9 451 Gene3D G3DSA:3.50.50.60 13 213 2.6E-11 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS39495 9e35de1531d545f31be5713646d191b9 451 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 12 355 1.0E-107 T 29-03-2018 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase SMALA_RS39495 9e35de1531d545f31be5713646d191b9 451 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 208 226 2.9E-6 T 29-03-2018 SMALA_RS39495 9e35de1531d545f31be5713646d191b9 451 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 15 34 2.9E-6 T 29-03-2018 SMALA_RS39495 9e35de1531d545f31be5713646d191b9 451 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 165 183 2.9E-6 T 29-03-2018 SMALA_RS39495 9e35de1531d545f31be5713646d191b9 451 SUPERFAMILY SSF51905 13 242 4.59E-18 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS39495 9e35de1531d545f31be5713646d191b9 451 SUPERFAMILY SSF51905 204 354 1.05E-7 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS39495 9e35de1531d545f31be5713646d191b9 451 Gene3D G3DSA:3.50.50.60 214 449 2.9E-15 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS06595 60623268fce7bd3c5593711f2b628b7f 121 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 12 116 3.2E-10 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMALA_RS06595 60623268fce7bd3c5593711f2b628b7f 121 Gene3D G3DSA:3.10.180.10 7 120 1.2E-21 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS06595 60623268fce7bd3c5593711f2b628b7f 121 SUPERFAMILY SSF54593 9 118 1.88E-21 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS22550 4d1b82243af5b9a08c6e4e24c432b1f6 278 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 273 47.417 T 29-03-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 SMALA_RS22550 4d1b82243af5b9a08c6e4e24c432b1f6 278 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 273 5.2E-127 T 29-03-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 SMALA_RS22550 4d1b82243af5b9a08c6e4e24c432b1f6 278 Gene3D G3DSA:2.30.30.30 120 196 2.2E-27 T 29-03-2018 IPR014722 Ribosomal protein L2 domain 2 SMALA_RS22550 4d1b82243af5b9a08c6e4e24c432b1f6 278 SMART SM01382 125 253 5.7E-87 T 29-03-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 SMALA_RS22550 4d1b82243af5b9a08c6e4e24c432b1f6 278 SMART SM01383 42 119 9.9E-40 T 29-03-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS22550 4d1b82243af5b9a08c6e4e24c432b1f6 278 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 126 251 5.3E-54 T 29-03-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 SMALA_RS22550 4d1b82243af5b9a08c6e4e24c432b1f6 278 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 118 9.3E-33 T 29-03-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS22550 4d1b82243af5b9a08c6e4e24c432b1f6 278 Gene3D G3DSA:4.10.950.10 198 273 9.1E-31 T 29-03-2018 IPR014726 Ribosomal protein L2, domain 3 SMALA_RS22550 4d1b82243af5b9a08c6e4e24c432b1f6 278 Gene3D G3DSA:2.40.50.140 1 115 3.3E-46 T 29-03-2018 SMALA_RS22550 4d1b82243af5b9a08c6e4e24c432b1f6 278 PIRSF PIRSF002158 4 275 1.9E-92 T 29-03-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS22550 4d1b82243af5b9a08c6e4e24c432b1f6 278 SUPERFAMILY SSF50249 3 126 7.2E-49 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMALA_RS22550 4d1b82243af5b9a08c6e4e24c432b1f6 278 SUPERFAMILY SSF50104 127 271 2.47E-55 T 29-03-2018 IPR008991 Translation protein SH3-like domain SMALA_RS22550 4d1b82243af5b9a08c6e4e24c432b1f6 278 ProSitePatterns PS00467 Ribosomal protein L2 signature. 219 230 - T 29-03-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMALA_RS00170 7206c4f06d9c622f680012341229dd8a 154 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 3 20 5.5E-17 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 SMALA_RS00170 7206c4f06d9c622f680012341229dd8a 154 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 78 93 5.5E-17 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 SMALA_RS00170 7206c4f06d9c622f680012341229dd8a 154 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 46 62 5.5E-17 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 SMALA_RS00170 7206c4f06d9c622f680012341229dd8a 154 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 119 134 5.5E-17 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 SMALA_RS00170 7206c4f06d9c622f680012341229dd8a 154 SUPERFAMILY SSF52788 2 148 1.14E-39 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily SMALA_RS00170 7206c4f06d9c622f680012341229dd8a 154 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 3 145 2.2E-34 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily SMALA_RS00170 7206c4f06d9c622f680012341229dd8a 154 SMART SM00226 1 147 1.0E-39 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily SMALA_RS00170 7206c4f06d9c622f680012341229dd8a 154 Gene3D G3DSA:3.40.50.2300 1 153 3.1E-43 T 29-03-2018 SMALA_RS26225 0e76fe749bb9446d7525abcaf2f5c5c7 168 Pfam PF00583 Acetyltransferase (GNAT) family 38 143 2.3E-14 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SMALA_RS26225 0e76fe749bb9446d7525abcaf2f5c5c7 168 SUPERFAMILY SSF55729 1 156 1.49E-25 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS26225 0e76fe749bb9446d7525abcaf2f5c5c7 168 Gene3D G3DSA:3.40.630.30 1 165 2.3E-26 T 29-03-2018 SMALA_RS23320 f437883ba26a815cb63b6b4b50021f1a 199 SUPERFAMILY SSF46689 17 82 5.64E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS23320 f437883ba26a815cb63b6b4b50021f1a 199 Gene3D G3DSA:1.10.10.60 2 70 3.1E-19 T 29-03-2018 SMALA_RS23320 f437883ba26a815cb63b6b4b50021f1a 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 28 74 8.0E-15 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS23320 f437883ba26a815cb63b6b4b50021f1a 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 49 72 2.4E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS23320 f437883ba26a815cb63b6b4b50021f1a 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 41 2.4E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS23320 f437883ba26a815cb63b6b4b50021f1a 199 Gene3D G3DSA:1.10.357.10 71 199 6.0E-11 T 29-03-2018 SMALA_RS23320 f437883ba26a815cb63b6b4b50021f1a 199 SUPERFAMILY SSF48498 93 197 6.68E-10 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS37215 d7a9de7c2be9b1c0cc7dc602d668afb8 964 Gene3D G3DSA:1.25.40.10 553 898 3.9E-27 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS37215 d7a9de7c2be9b1c0cc7dc602d668afb8 964 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 889 903 5.4E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS37215 d7a9de7c2be9b1c0cc7dc602d668afb8 964 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 919 931 5.4E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS37215 d7a9de7c2be9b1c0cc7dc602d668afb8 964 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 903 919 5.4E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS37215 d7a9de7c2be9b1c0cc7dc602d668afb8 964 Gene3D G3DSA:1.25.40.10 213 552 2.0E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS37215 d7a9de7c2be9b1c0cc7dc602d668afb8 964 SUPERFAMILY SSF46894 878 943 3.74E-15 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS37215 d7a9de7c2be9b1c0cc7dc602d668afb8 964 Gene3D G3DSA:1.10.10.10 899 946 1.2E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS37215 d7a9de7c2be9b1c0cc7dc602d668afb8 964 ProSitePatterns PS00622 LuxR-type HTH domain signature. 903 930 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS37215 d7a9de7c2be9b1c0cc7dc602d668afb8 964 Pfam PF00196 Bacterial regulatory proteins, luxR family 888 942 2.8E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS37215 d7a9de7c2be9b1c0cc7dc602d668afb8 964 SUPERFAMILY SSF48452 590 728 3.16E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS37215 d7a9de7c2be9b1c0cc7dc602d668afb8 964 SUPERFAMILY SSF48452 745 858 5.55E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS37215 d7a9de7c2be9b1c0cc7dc602d668afb8 964 Pfam PF13191 AAA ATPase domain 14 181 2.5E-22 T 29-03-2018 SMALA_RS37215 d7a9de7c2be9b1c0cc7dc602d668afb8 964 SUPERFAMILY SSF52540 13 97 5.02E-15 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS37215 d7a9de7c2be9b1c0cc7dc602d668afb8 964 SUPERFAMILY SSF52540 146 266 5.02E-15 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS37215 d7a9de7c2be9b1c0cc7dc602d668afb8 964 Gene3D G3DSA:3.40.50.300 3 195 3.0E-11 T 29-03-2018 SMALA_RS37215 d7a9de7c2be9b1c0cc7dc602d668afb8 964 SUPERFAMILY SSF48452 395 530 6.48E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS37215 d7a9de7c2be9b1c0cc7dc602d668afb8 964 SMART SM00421 886 943 4.7E-18 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS31480 58c335d136d4eae9b965b1ec7badc054 218 Hamap MF_02114 2-phospho-L-lactate guanylyltransferase [cofC]. 10 216 21.323 T 29-03-2018 IPR002835 2-phospho-L-lactate guanylyltransferase, CofC GO:0016779 KEGG: 00680+2.7.7.68|MetaCyc: PWY-5198 SMALA_RS31480 58c335d136d4eae9b965b1ec7badc054 218 Pfam PF01983 Guanylyl transferase CofC like 12 171 1.4E-8 T 29-03-2018 IPR002835 2-phospho-L-lactate guanylyltransferase, CofC GO:0016779 KEGG: 00680+2.7.7.68|MetaCyc: PWY-5198 SMALA_RS31480 58c335d136d4eae9b965b1ec7badc054 218 Gene3D G3DSA:3.90.550.10 7 184 9.7E-16 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS31480 58c335d136d4eae9b965b1ec7badc054 218 SUPERFAMILY SSF53448 10 210 5.28E-24 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS31480 58c335d136d4eae9b965b1ec7badc054 218 TIGRFAM TIGR03552 F420_cofC: 2-phospho-L-lactate guanylyltransferase 12 209 1.1E-36 T 29-03-2018 IPR002835 2-phospho-L-lactate guanylyltransferase, CofC GO:0016779 KEGG: 00680+2.7.7.68|MetaCyc: PWY-5198 SMALA_RS02375 0eeac1125e96871db34398503a469ea9 970 Pfam PF00196 Bacterial regulatory proteins, luxR family 915 968 6.7E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS02375 0eeac1125e96871db34398503a469ea9 970 Gene3D G3DSA:1.25.40.10 694 923 2.2E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS02375 0eeac1125e96871db34398503a469ea9 970 Gene3D G3DSA:3.40.50.300 52 229 1.3E-9 T 29-03-2018 SMALA_RS02375 0eeac1125e96871db34398503a469ea9 970 Gene3D G3DSA:1.10.10.10 308 388 0.006 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS02375 0eeac1125e96871db34398503a469ea9 970 Gene3D G3DSA:1.25.40.10 389 693 1.3E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS02375 0eeac1125e96871db34398503a469ea9 970 SUPERFAMILY SSF52540 50 110 2.38E-10 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS02375 0eeac1125e96871db34398503a469ea9 970 SUPERFAMILY SSF52540 154 292 2.38E-10 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS02375 0eeac1125e96871db34398503a469ea9 970 Pfam PF13191 AAA ATPase domain 52 208 9.0E-15 T 29-03-2018 SMALA_RS02375 0eeac1125e96871db34398503a469ea9 970 SMART SM00421 913 970 3.4E-20 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS02375 0eeac1125e96871db34398503a469ea9 970 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 946 958 2.7E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS02375 0eeac1125e96871db34398503a469ea9 970 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 916 930 2.7E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS02375 0eeac1125e96871db34398503a469ea9 970 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 930 946 2.7E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS02375 0eeac1125e96871db34398503a469ea9 970 SUPERFAMILY SSF46894 906 968 1.8E-15 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS02375 0eeac1125e96871db34398503a469ea9 970 Gene3D G3DSA:1.10.10.10 924 969 5.3E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS02375 0eeac1125e96871db34398503a469ea9 970 ProSitePatterns PS00622 LuxR-type HTH domain signature. 930 957 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS35565 a404907f163271d2bd7228d86f02664f 656 SUPERFAMILY SSF46689 565 654 4.35E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS35565 a404907f163271d2bd7228d86f02664f 656 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 617 634 1.8E-10 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 SMALA_RS35565 a404907f163271d2bd7228d86f02664f 656 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 634 654 1.8E-10 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 SMALA_RS35565 a404907f163271d2bd7228d86f02664f 656 Gene3D G3DSA:1.10.8.60 530 601 1.3E-11 T 29-03-2018 SMALA_RS35565 a404907f163271d2bd7228d86f02664f 656 Gene3D G3DSA:3.40.50.300 363 529 8.3E-8 T 29-03-2018 SMALA_RS35565 a404907f163271d2bd7228d86f02664f 656 Gene3D G3DSA:1.10.10.60 609 653 9.0E-15 T 29-03-2018 SMALA_RS35565 a404907f163271d2bd7228d86f02664f 656 Pfam PF02954 Bacterial regulatory protein, Fis family 612 651 2.4E-13 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 SMALA_RS35565 a404907f163271d2bd7228d86f02664f 656 SUPERFAMILY SSF52540 387 584 2.87E-18 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS08010 eae2134f2045546b77e48748b71f63b9 168 Gene3D G3DSA:3.10.20.30 2 76 4.4E-21 T 29-03-2018 IPR012675 Beta-grasp domain SMALA_RS08010 eae2134f2045546b77e48748b71f63b9 168 Gene3D G3DSA:1.10.150.120 77 168 1.9E-30 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 SMALA_RS08010 eae2134f2045546b77e48748b71f63b9 168 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 8 52 2.7E-7 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SMALA_RS08010 eae2134f2045546b77e48748b71f63b9 168 Pfam PF01799 [2Fe-2S] binding domain 75 162 9.4E-27 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 SMALA_RS08010 eae2134f2045546b77e48748b71f63b9 168 SUPERFAMILY SSF47741 81 167 3.01E-25 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 SMALA_RS08010 eae2134f2045546b77e48748b71f63b9 168 SUPERFAMILY SSF54292 2 80 8.65E-21 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SMALA_RS08010 eae2134f2045546b77e48748b71f63b9 168 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 41 49 - T 29-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 SMALA_RS18660 69a5a0b2f00a655f42d39b40412f8ef0 325 Gene3D G3DSA:3.40.50.300 2 324 1.2E-55 T 29-03-2018 SMALA_RS18660 69a5a0b2f00a655f42d39b40412f8ef0 325 SUPERFAMILY SSF52540 4 225 1.39E-28 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS18660 69a5a0b2f00a655f42d39b40412f8ef0 325 Pfam PF02374 Anion-transporting ATPase 6 161 8.8E-18 T 29-03-2018 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 SMALA_RS01430 053597c6a2135f1c277734208d306fdc 379 Gene3D G3DSA:3.40.50.2000 198 335 2.3E-40 T 29-03-2018 SMALA_RS01430 053597c6a2135f1c277734208d306fdc 379 Gene3D G3DSA:3.40.50.2000 1 197 5.2E-68 T 29-03-2018 SMALA_RS01430 053597c6a2135f1c277734208d306fdc 379 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 19 354 4.8E-111 T 29-03-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001 SMALA_RS01430 053597c6a2135f1c277734208d306fdc 379 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 1 355 2.2E-131 T 29-03-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 SMALA_RS01430 053597c6a2135f1c277734208d306fdc 379 SUPERFAMILY SSF53756 1 359 4.4E-116 T 29-03-2018 SMALA_RS37395 7cd6ba5d51b9fb02d82dd105c9e49c90 244 SMART SM00862 165 239 2.5E-27 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS37395 7cd6ba5d51b9fb02d82dd105c9e49c90 244 SMART SM00448 18 129 3.5E-39 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS37395 7cd6ba5d51b9fb02d82dd105c9e49c90 244 Pfam PF00072 Response regulator receiver domain 20 129 9.2E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS37395 7cd6ba5d51b9fb02d82dd105c9e49c90 244 Gene3D G3DSA:3.40.50.2300 11 138 1.2E-35 T 29-03-2018 SMALA_RS37395 7cd6ba5d51b9fb02d82dd105c9e49c90 244 Pfam PF00486 Transcriptional regulatory protein, C terminal 167 239 3.5E-25 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS37395 7cd6ba5d51b9fb02d82dd105c9e49c90 244 SUPERFAMILY SSF52172 17 196 2.93E-40 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS37395 7cd6ba5d51b9fb02d82dd105c9e49c90 244 Gene3D G3DSA:1.10.10.10 139 244 3.1E-32 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS17360 a56cf3f454b3c930d9ad20f187892249 281 TIGRFAM TIGR03664 fut_nucase: futalosine hydrolase 130 264 1.9E-44 T 29-03-2018 IPR019963 Futalosine hydrolase GO:0009234|GO:0016799 KEGG: 00130+3.2.2.26|MetaCyc: PWY-7374 SMALA_RS17360 a56cf3f454b3c930d9ad20f187892249 281 Gene3D G3DSA:3.40.50.1580 3 268 3.4E-46 T 29-03-2018 SMALA_RS17360 a56cf3f454b3c930d9ad20f187892249 281 Hamap MF_00991 Futalosine hydrolase [mqnB]. 36 267 25.516 T 29-03-2018 IPR019963 Futalosine hydrolase GO:0009234|GO:0016799 KEGG: 00130+3.2.2.26|MetaCyc: PWY-7374 SMALA_RS17360 a56cf3f454b3c930d9ad20f187892249 281 Pfam PF01048 Phosphorylase superfamily 130 261 6.8E-6 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 SMALA_RS17360 a56cf3f454b3c930d9ad20f187892249 281 SUPERFAMILY SSF53167 129 250 8.62E-18 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 SMALA_RS38715 7a846512a3b255389d5b552eb4d4e2d7 205 Gene3D G3DSA:3.40.140.10 9 131 1.7E-6 T 29-03-2018 SMALA_RS38715 7a846512a3b255389d5b552eb4d4e2d7 205 SUPERFAMILY SSF102712 11 64 3.14E-7 T 29-03-2018 SMALA_RS38715 7a846512a3b255389d5b552eb4d4e2d7 205 SUPERFAMILY SSF102712 97 169 3.14E-7 T 29-03-2018 SMALA_RS18805 8973b0c92a62880ba5c97ec77a038a2b 509 Gene3D G3DSA:1.20.1250.20 296 506 6.6E-33 T 29-03-2018 SMALA_RS18805 8973b0c92a62880ba5c97ec77a038a2b 509 SUPERFAMILY SSF103473 285 500 1.57E-71 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS18805 8973b0c92a62880ba5c97ec77a038a2b 509 SUPERFAMILY SSF103473 42 236 1.57E-71 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS18805 8973b0c92a62880ba5c97ec77a038a2b 509 Pfam PF07690 Major Facilitator Superfamily 55 448 3.2E-52 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS18805 8973b0c92a62880ba5c97ec77a038a2b 509 Gene3D G3DSA:1.20.1250.20 43 233 9.0E-33 T 29-03-2018 SMALA_RS18805 8973b0c92a62880ba5c97ec77a038a2b 509 ProSitePatterns PS00216 Sugar transport proteins signature 1. 104 120 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMALA_RS18805 8973b0c92a62880ba5c97ec77a038a2b 509 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 54 455 1.3E-79 T 29-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 SMALA_RS26860 40709068c85378e015903a27ccec04c4 281 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 55 278 1.8E-47 T 29-03-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 SMALA_RS26860 40709068c85378e015903a27ccec04c4 281 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 4 278 41.925 T 29-03-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 SMALA_RS26860 40709068c85378e015903a27ccec04c4 281 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 26 274 1.4E-70 T 29-03-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 SMALA_RS26860 40709068c85378e015903a27ccec04c4 281 Gene3D G3DSA:3.40.50.150 74 281 3.7E-44 T 29-03-2018 SMALA_RS26860 40709068c85378e015903a27ccec04c4 281 SUPERFAMILY SSF53335 17 251 1.23E-46 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS26860 40709068c85378e015903a27ccec04c4 281 Pfam PF05175 Methyltransferase small domain 114 187 1.2E-12 T 29-03-2018 IPR007848 Methyltransferase small domain GO:0008168 SMALA_RS26860 40709068c85378e015903a27ccec04c4 281 Gene3D G3DSA:1.10.8.10 4 73 8.3E-16 T 29-03-2018 SMALA_RS26860 40709068c85378e015903a27ccec04c4 281 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 181 187 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 SMALA_RS39660 c81b52c30f6154cc3bfaebb9ab8fa97e 268 SMART SM00382 33 232 1.8E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS39660 c81b52c30f6154cc3bfaebb9ab8fa97e 268 SUPERFAMILY SSF52540 4 253 1.49E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS39660 c81b52c30f6154cc3bfaebb9ab8fa97e 268 Gene3D G3DSA:3.40.50.300 1 267 2.0E-61 T 29-03-2018 SMALA_RS39660 c81b52c30f6154cc3bfaebb9ab8fa97e 268 Pfam PF00005 ABC transporter 25 183 4.3E-23 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS30175 d4beac02c7a4029441a2c085ec6e5462 293 SUPERFAMILY SSF161098 20 292 1.07E-69 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS30175 d4beac02c7a4029441a2c085ec6e5462 293 Gene3D G3DSA:1.10.3720.10 26 284 2.2E-49 T 29-03-2018 SMALA_RS30175 d4beac02c7a4029441a2c085ec6e5462 293 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 104 282 5.6E-22 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS05105 58c7acd5b4e8cc79a9178e4f0977f055 631 SUPERFAMILY SSF82171 21 252 5.76E-22 T 29-03-2018 SMALA_RS05105 58c7acd5b4e8cc79a9178e4f0977f055 631 SUPERFAMILY SSF82171 311 360 5.76E-22 T 29-03-2018 SMALA_RS05105 58c7acd5b4e8cc79a9178e4f0977f055 631 Gene3D G3DSA:2.130.10.120 148 354 4.7E-17 T 29-03-2018 SMALA_RS05105 58c7acd5b4e8cc79a9178e4f0977f055 631 Gene3D G3DSA:3.40.50.1820 355 631 8.3E-53 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS05105 58c7acd5b4e8cc79a9178e4f0977f055 631 SUPERFAMILY SSF53474 366 625 2.68E-71 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS05105 58c7acd5b4e8cc79a9178e4f0977f055 631 Pfam PF00326 Prolyl oligopeptidase family 412 626 1.5E-47 T 29-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 SMALA_RS05105 58c7acd5b4e8cc79a9178e4f0977f055 631 Gene3D G3DSA:2.140.10.30 8 147 3.9E-12 T 29-03-2018 SMALA_RS14690 6990fb187e124eb82f01f6a8b0714df0 325 SUPERFAMILY SSF55048 142 209 2.49E-13 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS14690 6990fb187e124eb82f01f6a8b0714df0 325 Gene3D G3DSA:3.40.366.10 17 152 7.0E-30 T 29-03-2018 SMALA_RS14690 6990fb187e124eb82f01f6a8b0714df0 325 Gene3D G3DSA:3.30.70.250 153 200 1.8E-19 T 29-03-2018 SMALA_RS14690 6990fb187e124eb82f01f6a8b0714df0 325 PIRSF PIRSF000446 16 322 4.3E-65 T 29-03-2018 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 SMALA_RS14690 6990fb187e124eb82f01f6a8b0714df0 325 Pfam PF00698 Acyl transferase domain 21 304 2.0E-35 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS14690 6990fb187e124eb82f01f6a8b0714df0 325 Gene3D G3DSA:3.40.366.10 201 323 3.4E-29 T 29-03-2018 SMALA_RS14690 6990fb187e124eb82f01f6a8b0714df0 325 SUPERFAMILY SSF52151 203 319 8.11E-58 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS14690 6990fb187e124eb82f01f6a8b0714df0 325 SUPERFAMILY SSF52151 18 135 8.11E-58 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS14690 6990fb187e124eb82f01f6a8b0714df0 325 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 21 320 2.0E-44 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS21990 31a29394dc7eeeec55f16419be44fed8 243 Pfam PF02441 Flavoprotein 26 211 6.2E-17 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 SMALA_RS21990 31a29394dc7eeeec55f16419be44fed8 243 SUPERFAMILY SSF52507 25 232 1.7E-44 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 SMALA_RS21990 31a29394dc7eeeec55f16419be44fed8 243 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 24 232 30.758 T 29-03-2018 IPR004507 Flavin prenyltransferase UbiX/Pad1 SMALA_RS21990 31a29394dc7eeeec55f16419be44fed8 243 Gene3D G3DSA:3.40.50.1950 25 242 4.4E-45 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 SMALA_RS21990 31a29394dc7eeeec55f16419be44fed8 243 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 108 230 2.4E-36 T 29-03-2018 IPR004507 Flavin prenyltransferase UbiX/Pad1 SMALA_RS00100 31a29394dc7eeeec55f16419be44fed8 243 Pfam PF02441 Flavoprotein 26 211 6.2E-17 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 SMALA_RS00100 31a29394dc7eeeec55f16419be44fed8 243 SUPERFAMILY SSF52507 25 232 1.7E-44 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 SMALA_RS00100 31a29394dc7eeeec55f16419be44fed8 243 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 24 232 30.758 T 29-03-2018 IPR004507 Flavin prenyltransferase UbiX/Pad1 SMALA_RS00100 31a29394dc7eeeec55f16419be44fed8 243 Gene3D G3DSA:3.40.50.1950 25 242 4.4E-45 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 SMALA_RS00100 31a29394dc7eeeec55f16419be44fed8 243 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 108 230 2.4E-36 T 29-03-2018 IPR004507 Flavin prenyltransferase UbiX/Pad1 SMALA_RS25850 8b3890bb4ffdde4ffe99fa44cb627d30 427 Gene3D G3DSA:3.10.580.10 276 421 1.6E-17 T 29-03-2018 SMALA_RS25850 8b3890bb4ffdde4ffe99fa44cb627d30 427 SUPERFAMILY SSF54631 281 417 1.26E-23 T 29-03-2018 SMALA_RS25850 8b3890bb4ffdde4ffe99fa44cb627d30 427 SUPERFAMILY SSF158791 166 278 5.62E-30 T 29-03-2018 SMALA_RS25850 8b3890bb4ffdde4ffe99fa44cb627d30 427 SUPERFAMILY SSF50346 11 88 4.08E-5 T 29-03-2018 IPR011033 PRC-barrel-like SMALA_RS25850 8b3890bb4ffdde4ffe99fa44cb627d30 427 SMART SM00116 357 405 2.2E-6 T 29-03-2018 IPR000644 CBS domain SMALA_RS25850 8b3890bb4ffdde4ffe99fa44cb627d30 427 Gene3D G3DSA:1.25.60.10 160 275 2.6E-26 T 29-03-2018 SMALA_RS25850 8b3890bb4ffdde4ffe99fa44cb627d30 427 Pfam PF00571 CBS domain 282 342 0.0029 T 29-03-2018 IPR000644 CBS domain SMALA_RS25850 8b3890bb4ffdde4ffe99fa44cb627d30 427 Pfam PF00571 CBS domain 357 405 1.0E-6 T 29-03-2018 IPR000644 CBS domain SMALA_RS25850 8b3890bb4ffdde4ffe99fa44cb627d30 427 Pfam PF03448 MgtE intracellular N domain 178 278 3.0E-27 T 29-03-2018 IPR006668 Magnesium transporter, MgtE intracellular domain SMALA_RS25850 8b3890bb4ffdde4ffe99fa44cb627d30 427 SMART SM00924 178 281 3.6E-35 T 29-03-2018 IPR006668 Magnesium transporter, MgtE intracellular domain SMALA_RS25850 8b3890bb4ffdde4ffe99fa44cb627d30 427 Gene3D G3DSA:2.30.30.240 8 77 9.7E-11 T 29-03-2018 SMALA_RS04235 47e62dfac1af643322543b04490d82a3 269 Gene3D G3DSA:3.90.226.10 13 221 5.5E-60 T 29-03-2018 SMALA_RS04235 47e62dfac1af643322543b04490d82a3 269 Pfam PF00378 Enoyl-CoA hydratase/isomerase 20 256 3.3E-48 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 SMALA_RS04235 47e62dfac1af643322543b04490d82a3 269 SUPERFAMILY SSF52096 13 256 2.68E-68 T 29-03-2018 IPR029045 ClpP/crotonase-like domain SMALA_RS04235 47e62dfac1af643322543b04490d82a3 269 Gene3D G3DSA:1.10.12.10 222 256 3.1E-5 T 29-03-2018 IPR014748 Crontonase, C-terminal SMALA_RS12780 e753bda9a99c129119c5bbb1fb8a6373 281 SUPERFAMILY SSF64005 34 257 5.89E-84 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 SMALA_RS12780 e753bda9a99c129119c5bbb1fb8a6373 281 Gene3D G3DSA:3.40.1180.10 25 264 8.8E-85 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 SMALA_RS12780 e753bda9a99c129119c5bbb1fb8a6373 281 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 34 262 38.223 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 SMALA_RS12780 e753bda9a99c129119c5bbb1fb8a6373 281 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 34 261 1.4E-78 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 SMALA_RS12780 e753bda9a99c129119c5bbb1fb8a6373 281 Pfam PF01255 Putative undecaprenyl diphosphate synthase 41 261 6.4E-74 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 SMALA_RS12780 e753bda9a99c129119c5bbb1fb8a6373 281 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 207 224 - T 29-03-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199 SMALA_RS03005 ecee8dd7dbcd3df148ac27cd04188ecf 85 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 80 8.4E-20 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS03005 ecee8dd7dbcd3df148ac27cd04188ecf 85 ProSitePatterns PS01143 Ribosomal protein L31 signature. 49 70 - T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS03005 ecee8dd7dbcd3df148ac27cd04188ecf 85 PRINTS PR01249 Ribosomal protein L31 signature 60 78 1.4E-19 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS03005 ecee8dd7dbcd3df148ac27cd04188ecf 85 PRINTS PR01249 Ribosomal protein L31 signature 2 19 1.4E-19 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS03005 ecee8dd7dbcd3df148ac27cd04188ecf 85 PRINTS PR01249 Ribosomal protein L31 signature 45 60 1.4E-19 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS03005 ecee8dd7dbcd3df148ac27cd04188ecf 85 Hamap MF_00502 50S ribosomal protein L31 type B [rpmE2]. 1 81 26.161 T 29-03-2018 IPR027493 Ribosomal protein L31 type B GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS03005 ecee8dd7dbcd3df148ac27cd04188ecf 85 Pfam PF01197 Ribosomal protein L31 1 79 3.4E-30 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS03005 ecee8dd7dbcd3df148ac27cd04188ecf 85 SUPERFAMILY SSF143800 1 79 7.85E-23 T 29-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS15620 e646914dfe0ee257b4e669de82957eac 1666 Pfam PF05088 Bacterial NAD-glutamate dehydrogenase 83 1659 0.0 T 29-03-2018 IPR028971 NAD-glutamate dehydrogenase GO:0004352|GO:0019551 KEGG: 00220+1.4.1.2|KEGG: 00250+1.4.1.2|KEGG: 00430+1.4.1.2|KEGG: 00910+1.4.1.2|MetaCyc: PWY-5022|MetaCyc: PWY-6728|MetaCyc: PWY-7126 SMALA_RS15620 e646914dfe0ee257b4e669de82957eac 1666 SUPERFAMILY SSF53223 822 996 3.36E-21 T 29-03-2018 SMALA_RS15620 e646914dfe0ee257b4e669de82957eac 1666 SUPERFAMILY SSF51735 1141 1340 1.58E-32 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS15620 e646914dfe0ee257b4e669de82957eac 1666 SUPERFAMILY SSF51735 1001 1103 1.58E-32 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS15620 e646914dfe0ee257b4e669de82957eac 1666 PIRSF PIRSF036761 2 1666 0.0 T 29-03-2018 IPR007780 NAD-glutamate dehydrogenase, bacteria GO:0004352|GO:0019551 SMALA_RS15620 e646914dfe0ee257b4e669de82957eac 1666 Gene3D G3DSA:3.40.50.720 994 1347 6.4E-55 T 29-03-2018 SMALA_RS22645 83cf7e0abd16698376a66c64b32120f4 218 Pfam PF00406 Adenylate kinase 5 191 9.6E-58 T 29-03-2018 SMALA_RS22645 83cf7e0abd16698376a66c64b32120f4 218 Gene3D G3DSA:3.40.50.300 1 218 8.9E-62 T 29-03-2018 SMALA_RS22645 83cf7e0abd16698376a66c64b32120f4 218 PRINTS PR00094 Adenylate kinase signature 81 97 3.0E-36 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 SMALA_RS22645 83cf7e0abd16698376a66c64b32120f4 218 PRINTS PR00094 Adenylate kinase signature 32 46 3.0E-36 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 SMALA_RS22645 83cf7e0abd16698376a66c64b32120f4 218 PRINTS PR00094 Adenylate kinase signature 4 17 3.0E-36 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 SMALA_RS22645 83cf7e0abd16698376a66c64b32120f4 218 PRINTS PR00094 Adenylate kinase signature 178 192 3.0E-36 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 SMALA_RS22645 83cf7e0abd16698376a66c64b32120f4 218 PRINTS PR00094 Adenylate kinase signature 161 176 3.0E-36 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 SMALA_RS22645 83cf7e0abd16698376a66c64b32120f4 218 Pfam PF05191 Adenylate kinase, active site lid 127 163 1.1E-12 T 29-03-2018 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 SMALA_RS22645 83cf7e0abd16698376a66c64b32120f4 218 TIGRFAM TIGR01351 adk: adenylate kinase 2 213 3.9E-77 T 29-03-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 SMALA_RS22645 83cf7e0abd16698376a66c64b32120f4 218 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 29-03-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 SMALA_RS22645 83cf7e0abd16698376a66c64b32120f4 218 Hamap MF_00235 Adenylate kinase [adk]. 1 214 50.111 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 SMALA_RS22645 83cf7e0abd16698376a66c64b32120f4 218 SUPERFAMILY SSF52540 1 215 1.74E-42 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS33550 d9a629423e1b0985a699e1ee574bb9ff 532 Pfam PF04820 Tryptophan halogenase 15 494 2.8E-141 T 29-03-2018 IPR006905 Flavin-dependent halogenase SMALA_RS33550 d9a629423e1b0985a699e1ee574bb9ff 532 SUPERFAMILY SSF51905 164 261 6.26E-29 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS33550 d9a629423e1b0985a699e1ee574bb9ff 532 SUPERFAMILY SSF51905 350 434 6.26E-29 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS33550 d9a629423e1b0985a699e1ee574bb9ff 532 SUPERFAMILY SSF51905 15 97 6.26E-29 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS33550 d9a629423e1b0985a699e1ee574bb9ff 532 PIRSF PIRSF011396 8 531 1.6E-150 T 29-03-2018 IPR033856 Flavin-dependent tryptophan halogenase SMALA_RS33550 d9a629423e1b0985a699e1ee574bb9ff 532 Gene3D G3DSA:3.50.50.60 7 390 9.7E-35 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS39515 0f22e6e393b71b48fcbefa727e01cdf1 349 SUPERFAMILY SSF53807 54 344 1.61E-51 T 29-03-2018 SMALA_RS39515 0f22e6e393b71b48fcbefa727e01cdf1 349 Gene3D G3DSA:3.40.50.1980 40 186 7.9E-30 T 29-03-2018 SMALA_RS39515 0f22e6e393b71b48fcbefa727e01cdf1 349 Gene3D G3DSA:3.40.50.1980 187 349 1.2E-26 T 29-03-2018 SMALA_RS39515 0f22e6e393b71b48fcbefa727e01cdf1 349 Pfam PF01497 Periplasmic binding protein 112 319 1.1E-25 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 SMALA_RS02680 d72be7554c95c183587f421d6de0ee3a 424 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 38 139 1.5E-7 T 29-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain SMALA_RS02680 d72be7554c95c183587f421d6de0ee3a 424 SMART SM00922 173 267 1.2E-23 T 29-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal SMALA_RS02680 d72be7554c95c183587f421d6de0ee3a 424 SUPERFAMILY SSF51604 139 396 4.42E-74 T 29-03-2018 IPR029065 Enolase C-terminal domain-like SMALA_RS02680 d72be7554c95c183587f421d6de0ee3a 424 Pfam PF13378 Enolase C-terminal domain-like 176 387 1.7E-51 T 29-03-2018 IPR029065 Enolase C-terminal domain-like SMALA_RS02680 d72be7554c95c183587f421d6de0ee3a 424 Gene3D G3DSA:3.20.20.120 147 396 1.9E-58 T 29-03-2018 IPR029065 Enolase C-terminal domain-like SMALA_RS02680 d72be7554c95c183587f421d6de0ee3a 424 Gene3D G3DSA:3.30.390.10 7 146 7.0E-32 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMALA_RS02680 d72be7554c95c183587f421d6de0ee3a 424 SUPERFAMILY SSF54826 7 139 3.36E-26 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMALA_RS18745 fa7d82f40530bd00a38c1bd4e22902cb 124 Pfam PF12680 SnoaL-like domain 8 101 4.0E-13 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain SMALA_RS18745 fa7d82f40530bd00a38c1bd4e22902cb 124 SUPERFAMILY SSF54427 1 123 1.2E-26 T 29-03-2018 IPR032710 NTF2-like domain SMALA_RS18745 fa7d82f40530bd00a38c1bd4e22902cb 124 Gene3D G3DSA:3.10.450.50 1 124 7.6E-21 T 29-03-2018 SMALA_RS26375 00a8729a62c9b1c199ec0fb312659186 303 Gene3D G3DSA:3.40.710.10 1 303 1.8E-130 T 29-03-2018 SMALA_RS26375 00a8729a62c9b1c199ec0fb312659186 303 Hamap MF_00313 Glutaminase [glsA]. 3 303 45.694 T 29-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 SMALA_RS26375 00a8729a62c9b1c199ec0fb312659186 303 Pfam PF04960 Glutaminase 21 303 1.2E-108 T 29-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 SMALA_RS26375 00a8729a62c9b1c199ec0fb312659186 303 SUPERFAMILY SSF56601 2 303 1.45E-105 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMALA_RS26375 00a8729a62c9b1c199ec0fb312659186 303 TIGRFAM TIGR03814 Gln_ase: glutaminase A 7 303 1.6E-122 T 29-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 SMALA_RS21685 5a5334e130c8c9b398aad979a43267a1 309 SUPERFAMILY SSF53067 2 125 1.02E-30 T 29-03-2018 SMALA_RS21685 5a5334e130c8c9b398aad979a43267a1 309 Gene3D G3DSA:3.30.420.150 127 307 1.8E-42 T 29-03-2018 SMALA_RS21685 5a5334e130c8c9b398aad979a43267a1 309 Gene3D G3DSA:3.30.420.40 1 124 5.4E-37 T 29-03-2018 SMALA_RS21685 5a5334e130c8c9b398aad979a43267a1 309 Pfam PF02541 Ppx/GppA phosphatase family 28 305 1.7E-73 T 29-03-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 SMALA_RS21685 5a5334e130c8c9b398aad979a43267a1 309 SUPERFAMILY SSF53067 129 306 6.47E-37 T 29-03-2018 SMALA_RS01285 2b6df5595c3822003cba267330de4af1 501 Hamap MF_00186 Glycerol kinase [glpK]. 3 499 52.026 T 29-03-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 SMALA_RS01285 2b6df5595c3822003cba267330de4af1 501 SUPERFAMILY SSF53067 256 499 4.26E-77 T 29-03-2018 SMALA_RS01285 2b6df5595c3822003cba267330de4af1 501 PIRSF PIRSF000538 3 501 6.3E-158 T 29-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 SMALA_RS01285 2b6df5595c3822003cba267330de4af1 501 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 5 498 1.3E-207 T 29-03-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 SMALA_RS01285 2b6df5595c3822003cba267330de4af1 501 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 364 384 - T 29-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 SMALA_RS01285 2b6df5595c3822003cba267330de4af1 501 Gene3D G3DSA:3.30.420.40 1 249 4.0E-87 T 29-03-2018 SMALA_RS01285 2b6df5595c3822003cba267330de4af1 501 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 262 452 1.2E-61 T 29-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 SMALA_RS01285 2b6df5595c3822003cba267330de4af1 501 Gene3D G3DSA:3.30.420.40 250 501 6.2E-76 T 29-03-2018 SMALA_RS01285 2b6df5595c3822003cba267330de4af1 501 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 5 253 1.0E-72 T 29-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 SMALA_RS01285 2b6df5595c3822003cba267330de4af1 501 SUPERFAMILY SSF53067 5 256 3.11E-85 T 29-03-2018 SMALA_RS16745 0e3c81fa331ab8bc928db3884aa879be 199 Gene3D G3DSA:3.90.1140.10 3 181 3.8E-29 T 29-03-2018 SMALA_RS16745 0e3c81fa331ab8bc928db3884aa879be 199 SUPERFAMILY SSF55144 5 173 2.09E-30 T 29-03-2018 IPR009097 Cyclic phosphodiesterase SMALA_RS16745 0e3c81fa331ab8bc928db3884aa879be 199 Pfam PF13563 2'-5' RNA ligase superfamily 13 158 5.9E-21 T 29-03-2018 SMALA_RS21055 9af62f59a5512e87b7e53df8fa265332 795 SMART SM00487 109 309 2.5E-52 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain SMALA_RS21055 9af62f59a5512e87b7e53df8fa265332 795 Gene3D G3DSA:3.40.50.300 313 530 1.7E-36 T 29-03-2018 SMALA_RS21055 9af62f59a5512e87b7e53df8fa265332 795 Pfam PF00270 DEAD/DEAH box helicase 114 282 3.5E-43 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 SMALA_RS21055 9af62f59a5512e87b7e53df8fa265332 795 Pfam PF00271 Helicase conserved C-terminal domain 327 424 8.7E-23 T 29-03-2018 IPR001650 Helicase, C-terminal SMALA_RS21055 9af62f59a5512e87b7e53df8fa265332 795 SUPERFAMILY SSF52540 161 445 3.23E-64 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS21055 9af62f59a5512e87b7e53df8fa265332 795 SMART SM00490 343 424 2.6E-28 T 29-03-2018 IPR001650 Helicase, C-terminal SMALA_RS21055 9af62f59a5512e87b7e53df8fa265332 795 Gene3D G3DSA:3.40.50.300 24 312 2.2E-57 T 29-03-2018 SMALA_RS15430 f365d9b196c5f3628394c9aef3e07d55 297 Gene3D G3DSA:3.40.190.10 178 269 2.5E-23 T 29-03-2018 SMALA_RS15430 f365d9b196c5f3628394c9aef3e07d55 297 Gene3D G3DSA:3.40.190.10 92 177 2.4E-22 T 29-03-2018 SMALA_RS15430 f365d9b196c5f3628394c9aef3e07d55 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.4E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS15430 f365d9b196c5f3628394c9aef3e07d55 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.4E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS15430 f365d9b196c5f3628394c9aef3e07d55 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.4E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS15430 f365d9b196c5f3628394c9aef3e07d55 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 7.2E-21 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS15430 f365d9b196c5f3628394c9aef3e07d55 297 Gene3D G3DSA:1.10.10.10 1 91 1.3E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS15430 f365d9b196c5f3628394c9aef3e07d55 297 SUPERFAMILY SSF46785 1 85 4.14E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS15430 f365d9b196c5f3628394c9aef3e07d55 297 Pfam PF03466 LysR substrate binding domain 87 294 2.5E-39 T 29-03-2018 IPR005119 LysR, substrate-binding SMALA_RS15430 f365d9b196c5f3628394c9aef3e07d55 297 SUPERFAMILY SSF53850 88 295 1.86E-36 T 29-03-2018 SMALA_RS07635 dc654d1c5e0ced71c871fc77c3727caf 587 Gene3D G3DSA:3.40.50.410 391 577 3.7E-10 T 29-03-2018 IPR002035 von Willebrand factor, type A SMALA_RS07635 dc654d1c5e0ced71c871fc77c3727caf 587 SUPERFAMILY SSF53300 418 554 8.9E-9 T 29-03-2018 IPR002035 von Willebrand factor, type A SMALA_RS07635 dc654d1c5e0ced71c871fc77c3727caf 587 Pfam PF05762 VWA domain containing CoxE-like protein 361 549 2.1E-8 T 29-03-2018 IPR008912 Uncharacterised protein family CoxE-like SMALA_RS20835 5b3f2d17c158658ef1f137b943a322f0 239 SMART SM00345 16 74 6.9E-11 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS20835 5b3f2d17c158658ef1f137b943a322f0 239 SUPERFAMILY SSF48008 80 218 2.88E-16 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS20835 5b3f2d17c158658ef1f137b943a322f0 239 Pfam PF07729 FCD domain 100 207 8.4E-13 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS20835 5b3f2d17c158658ef1f137b943a322f0 239 SUPERFAMILY SSF46785 6 83 6.13E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS20835 5b3f2d17c158658ef1f137b943a322f0 239 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 74 2.9E-15 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS20835 5b3f2d17c158658ef1f137b943a322f0 239 Gene3D G3DSA:1.20.120.530 77 231 7.4E-47 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS20835 5b3f2d17c158658ef1f137b943a322f0 239 Gene3D G3DSA:1.10.10.10 4 76 7.6E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS35780 f46e0cb419919c6fbdee65d1d5e9f854 285 Pfam PF13560 Helix-turn-helix domain 15 74 4.8E-14 T 29-03-2018 SMALA_RS35780 f46e0cb419919c6fbdee65d1d5e9f854 285 SUPERFAMILY SSF47413 13 73 4.56E-9 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS35780 f46e0cb419919c6fbdee65d1d5e9f854 285 SMART SM00530 18 73 1.9E-7 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS35780 f46e0cb419919c6fbdee65d1d5e9f854 285 Gene3D G3DSA:1.10.3100.10 11 161 1.0E-13 T 29-03-2018 IPR027910 YdiL-like domain SMALA_RS29410 09ea1b3e7f025cea6528be6ebea041f1 416 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 14 251 7.1E-30 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS29410 09ea1b3e7f025cea6528be6ebea041f1 416 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 259 368 4.6E-31 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS29410 09ea1b3e7f025cea6528be6ebea041f1 416 SUPERFAMILY SSF53901 15 256 1.01E-47 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS29410 09ea1b3e7f025cea6528be6ebea041f1 416 SMART SM00825 Beta-ketoacyl synthase 16 414 5.7E-16 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS29410 09ea1b3e7f025cea6528be6ebea041f1 416 SUPERFAMILY SSF53901 223 412 1.53E-61 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS29410 09ea1b3e7f025cea6528be6ebea041f1 416 Gene3D G3DSA:3.40.47.10 265 412 5.3E-42 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS29410 09ea1b3e7f025cea6528be6ebea041f1 416 Gene3D G3DSA:3.40.47.10 16 264 1.5E-55 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS26220 aecfa747de91c9c9801bcecbb29bbb04 803 PRINTS PR01183 Ribonucleotide reductase large chain signature 303 322 5.3E-49 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMALA_RS26220 aecfa747de91c9c9801bcecbb29bbb04 803 PRINTS PR01183 Ribonucleotide reductase large chain signature 605 632 5.3E-49 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMALA_RS26220 aecfa747de91c9c9801bcecbb29bbb04 803 PRINTS PR01183 Ribonucleotide reductase large chain signature 539 562 5.3E-49 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMALA_RS26220 aecfa747de91c9c9801bcecbb29bbb04 803 PRINTS PR01183 Ribonucleotide reductase large chain signature 473 496 5.3E-49 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMALA_RS26220 aecfa747de91c9c9801bcecbb29bbb04 803 PRINTS PR01183 Ribonucleotide reductase large chain signature 435 446 5.3E-49 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMALA_RS26220 aecfa747de91c9c9801bcecbb29bbb04 803 PRINTS PR01183 Ribonucleotide reductase large chain signature 511 533 5.3E-49 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMALA_RS26220 aecfa747de91c9c9801bcecbb29bbb04 803 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 147 223 8.9E-19 T 29-03-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMALA_RS26220 aecfa747de91c9c9801bcecbb29bbb04 803 SUPERFAMILY SSF48168 26 225 1.05E-41 T 29-03-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMALA_RS26220 aecfa747de91c9c9801bcecbb29bbb04 803 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 594 616 - T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMALA_RS26220 aecfa747de91c9c9801bcecbb29bbb04 803 SUPERFAMILY SSF51998 226 654 4.27E-174 T 29-03-2018 SMALA_RS26220 aecfa747de91c9c9801bcecbb29bbb04 803 SUPERFAMILY SSF51998 685 755 4.27E-174 T 29-03-2018 SMALA_RS26220 aecfa747de91c9c9801bcecbb29bbb04 803 Pfam PF02867 Ribonucleotide reductase, barrel domain 227 750 2.6E-174 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMALA_RS26220 aecfa747de91c9c9801bcecbb29bbb04 803 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 150 754 7.8E-224 T 29-03-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMALA_RS26220 aecfa747de91c9c9801bcecbb29bbb04 803 Gene3D G3DSA:3.20.70.20 127 757 2.1E-199 T 29-03-2018 SMALA_RS22505 92e6a448cd8b1b7ec0fe37ab16813429 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 4.3E-64 T 29-03-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 SMALA_RS22505 92e6a448cd8b1b7ec0fe37ab16813429 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 34.73 T 29-03-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 SMALA_RS22505 92e6a448cd8b1b7ec0fe37ab16813429 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 29-03-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMALA_RS22505 92e6a448cd8b1b7ec0fe37ab16813429 156 PIRSF PIRSF002122 7 156 3.3E-54 T 29-03-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 SMALA_RS22505 92e6a448cd8b1b7ec0fe37ab16813429 156 SUPERFAMILY SSF47973 1 149 2.49E-56 T 29-03-2018 IPR023798 Ribosomal protein S7 domain SMALA_RS22505 92e6a448cd8b1b7ec0fe37ab16813429 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 2.6E-59 T 29-03-2018 IPR023798 Ribosomal protein S7 domain SMALA_RS22505 92e6a448cd8b1b7ec0fe37ab16813429 156 Gene3D G3DSA:1.10.455.10 6 156 2.2E-54 T 29-03-2018 IPR023798 Ribosomal protein S7 domain SMALA_RS13235 d8d1ba04ba4ed921494038df4ee55238 544 Pfam PF05697 Bacterial trigger factor protein (TF) 69 211 7.4E-43 T 29-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 SMALA_RS13235 d8d1ba04ba4ed921494038df4ee55238 544 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 324 486 4.0E-38 T 29-03-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 SMALA_RS13235 d8d1ba04ba4ed921494038df4ee55238 544 Gene3D G3DSA:3.30.70.1050 64 185 3.0E-37 T 29-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 SMALA_RS13235 d8d1ba04ba4ed921494038df4ee55238 544 Hamap MF_00303 Trigger factor [tig]. 67 491 19.817 T 29-03-2018 IPR005215 Trigger factor GO:0015031 SMALA_RS13235 d8d1ba04ba4ed921494038df4ee55238 544 TIGRFAM TIGR00115 tig: trigger factor 78 484 1.4E-124 T 29-03-2018 IPR005215 Trigger factor GO:0015031 SMALA_RS13235 d8d1ba04ba4ed921494038df4ee55238 544 SUPERFAMILY SSF54534 199 310 5.11E-21 T 29-03-2018 SMALA_RS13235 d8d1ba04ba4ed921494038df4ee55238 544 SUPERFAMILY SSF102735 69 197 2.35E-37 T 29-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 SMALA_RS13235 d8d1ba04ba4ed921494038df4ee55238 544 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 223 281 8.9E-7 T 29-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain SMALA_RS13235 d8d1ba04ba4ed921494038df4ee55238 544 Gene3D G3DSA:3.10.50.40 200 289 7.9E-7 T 29-03-2018 SMALA_RS13235 d8d1ba04ba4ed921494038df4ee55238 544 Gene3D G3DSA:1.10.3120.10 290 461 5.0E-41 T 29-03-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 SMALA_RS13235 d8d1ba04ba4ed921494038df4ee55238 544 SUPERFAMILY SSF109998 311 500 2.45E-39 T 29-03-2018 IPR027304 Trigger factor/SurA domain SMALA_RS05365 54425fa45a9f053409082bcb80c3b97a 154 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 9 153 9.0E-34 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 SMALA_RS05365 54425fa45a9f053409082bcb80c3b97a 154 TIGRFAM TIGR02133 RPI_actino: ribose 5-phosphate isomerase 7 153 3.8E-61 T 29-03-2018 IPR011860 Ribose 5-phosphate isomerase GO:0004751 SMALA_RS05365 54425fa45a9f053409082bcb80c3b97a 154 PIRSF PIRSF005384 7 154 2.3E-45 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 SMALA_RS05365 54425fa45a9f053409082bcb80c3b97a 154 Gene3D G3DSA:3.40.1400.10 5 154 1.4E-54 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 SMALA_RS05365 54425fa45a9f053409082bcb80c3b97a 154 SUPERFAMILY SSF89623 6 153 1.06E-46 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 SMALA_RS05365 54425fa45a9f053409082bcb80c3b97a 154 Pfam PF02502 Ribose/Galactose Isomerase 9 149 1.7E-44 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 SMALA_RS13545 d4f5a524234a6acc67fe362c00dbfee8 111 Gene3D G3DSA:1.10.10.60 1 52 7.1E-12 T 29-03-2018 SMALA_RS13545 d4f5a524234a6acc67fe362c00dbfee8 111 Gene3D G3DSA:1.10.10.60 53 104 2.2E-9 T 29-03-2018 SMALA_RS13545 d4f5a524234a6acc67fe362c00dbfee8 111 SUPERFAMILY SSF46689 2 48 1.08E-5 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS13545 d4f5a524234a6acc67fe362c00dbfee8 111 SUPERFAMILY SSF46689 52 102 1.43E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS13545 d4f5a524234a6acc67fe362c00dbfee8 111 Pfam PF12833 Helix-turn-helix domain 21 101 3.0E-22 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS13545 d4f5a524234a6acc67fe362c00dbfee8 111 SMART SM00342 15 101 6.4E-24 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS24185 683b34803cc42978bae404194c8ee167 267 Pfam PF00121 Triosephosphate isomerase 11 249 7.6E-48 T 29-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMALA_RS24185 683b34803cc42978bae404194c8ee167 267 Gene3D G3DSA:3.20.20.70 8 264 4.5E-69 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS24185 683b34803cc42978bae404194c8ee167 267 SUPERFAMILY SSF51351 8 254 3.67E-56 T 29-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMALA_RS03080 0e5551ede96afd538e031ebc1e6cdb2a 251 SUPERFAMILY SSF48008 101 230 4.97E-27 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS03080 0e5551ede96afd538e031ebc1e6cdb2a 251 Pfam PF00392 Bacterial regulatory proteins, gntR family 23 84 2.3E-18 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS03080 0e5551ede96afd538e031ebc1e6cdb2a 251 Pfam PF07729 FCD domain 102 223 1.3E-25 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS03080 0e5551ede96afd538e031ebc1e6cdb2a 251 SUPERFAMILY SSF46785 16 88 4.14E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS03080 0e5551ede96afd538e031ebc1e6cdb2a 251 Gene3D G3DSA:1.20.120.530 93 241 1.8E-29 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS03080 0e5551ede96afd538e031ebc1e6cdb2a 251 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 44 58 1.0E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS03080 0e5551ede96afd538e031ebc1e6cdb2a 251 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 58 74 1.0E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS03080 0e5551ede96afd538e031ebc1e6cdb2a 251 SMART SM00345 25 84 1.2E-21 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS03080 0e5551ede96afd538e031ebc1e6cdb2a 251 Gene3D G3DSA:1.10.10.10 13 86 2.2E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS03080 0e5551ede96afd538e031ebc1e6cdb2a 251 SMART SM00895 102 223 1.9E-19 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS01835 7e41d3db7ffc7852963b6cc0d7c4e7d0 524 ProSitePatterns PS00455 Putative AMP-binding domain signature. 171 182 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS01835 7e41d3db7ffc7852963b6cc0d7c4e7d0 524 Pfam PF00501 AMP-binding enzyme 32 423 2.1E-67 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS01835 7e41d3db7ffc7852963b6cc0d7c4e7d0 524 Gene3D G3DSA:3.40.50.980 177 332 9.1E-31 T 29-03-2018 SMALA_RS01835 7e41d3db7ffc7852963b6cc0d7c4e7d0 524 Gene3D G3DSA:3.40.50.980 18 176 5.8E-24 T 29-03-2018 SMALA_RS01835 7e41d3db7ffc7852963b6cc0d7c4e7d0 524 Gene3D G3DSA:2.30.38.10 333 416 2.1E-22 T 29-03-2018 SMALA_RS01835 7e41d3db7ffc7852963b6cc0d7c4e7d0 524 Pfam PF13193 AMP-binding enzyme C-terminal domain 433 507 6.2E-17 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS01835 7e41d3db7ffc7852963b6cc0d7c4e7d0 524 SUPERFAMILY SSF56801 21 519 4.84E-104 T 29-03-2018 SMALA_RS01835 7e41d3db7ffc7852963b6cc0d7c4e7d0 524 Gene3D G3DSA:3.30.300.30 417 521 1.4E-21 T 29-03-2018 SMALA_RS35590 bf23a20dfef917d0dd14685eb0639491 294 SUPERFAMILY SSF54427 176 287 2.44E-18 T 29-03-2018 IPR032710 NTF2-like domain SMALA_RS35590 bf23a20dfef917d0dd14685eb0639491 294 Gene3D G3DSA:1.10.1740.10 2 72 7.8E-17 T 29-03-2018 SMALA_RS35590 bf23a20dfef917d0dd14685eb0639491 294 Pfam PF08281 Sigma-70, region 4 111 161 2.2E-7 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS35590 bf23a20dfef917d0dd14685eb0639491 294 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 7 163 4.2E-14 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS35590 bf23a20dfef917d0dd14685eb0639491 294 Gene3D G3DSA:1.10.10.10 73 153 4.1E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS35590 bf23a20dfef917d0dd14685eb0639491 294 SUPERFAMILY SSF88659 105 163 9.35E-9 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS35590 bf23a20dfef917d0dd14685eb0639491 294 Pfam PF04542 Sigma-70 region 2 11 74 8.8E-14 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS35590 bf23a20dfef917d0dd14685eb0639491 294 Gene3D G3DSA:3.10.450.50 154 287 7.3E-25 T 29-03-2018 SMALA_RS35590 bf23a20dfef917d0dd14685eb0639491 294 SUPERFAMILY SSF88946 7 88 5.49E-15 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS26530 0f1dcf6e5faaca369d504aacd53e2c96 227 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 47 70 5.7E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS26530 0f1dcf6e5faaca369d504aacd53e2c96 227 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 39 5.7E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS26530 0f1dcf6e5faaca369d504aacd53e2c96 227 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 72 2.2E-15 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS26530 0f1dcf6e5faaca369d504aacd53e2c96 227 SUPERFAMILY SSF46689 17 85 9.98E-19 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS26530 0f1dcf6e5faaca369d504aacd53e2c96 227 Gene3D G3DSA:1.10.10.60 2 47 3.5E-16 T 29-03-2018 SMALA_RS26530 0f1dcf6e5faaca369d504aacd53e2c96 227 SUPERFAMILY SSF48498 104 223 7.69E-12 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS26530 0f1dcf6e5faaca369d504aacd53e2c96 227 Gene3D G3DSA:1.10.260.40 48 88 5.4E-12 T 29-03-2018 SMALA_RS26530 0f1dcf6e5faaca369d504aacd53e2c96 227 Pfam PF16859 Bacterial transcriptional repressor C-terminal 104 214 9.0E-9 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS26530 0f1dcf6e5faaca369d504aacd53e2c96 227 Gene3D G3DSA:1.10.357.10 95 227 2.5E-23 T 29-03-2018 SMALA_RS01960 4b72ec61304f311354874a40ffb23453 631 Pfam PF00703 Glycosyl hydrolases family 2 195 297 2.0E-7 T 29-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 SMALA_RS01960 4b72ec61304f311354874a40ffb23453 631 Gene3D G3DSA:2.60.40.10 195 290 7.8E-15 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS01960 4b72ec61304f311354874a40ffb23453 631 SUPERFAMILY SSF51445 295 479 3.01E-56 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS01960 4b72ec61304f311354874a40ffb23453 631 SUPERFAMILY SSF51445 511 615 3.01E-56 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS01960 4b72ec61304f311354874a40ffb23453 631 SUPERFAMILY SSF49785 15 193 1.23E-47 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS01960 4b72ec61304f311354874a40ffb23453 631 SUPERFAMILY SSF49303 200 297 1.76E-12 T 29-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 SMALA_RS01960 4b72ec61304f311354874a40ffb23453 631 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 300 490 3.9E-6 T 29-03-2018 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 SMALA_RS01960 4b72ec61304f311354874a40ffb23453 631 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 33 153 3.9E-12 T 29-03-2018 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 SMALA_RS01960 4b72ec61304f311354874a40ffb23453 631 Gene3D G3DSA:2.60.120.260 15 193 9.5E-41 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS01960 4b72ec61304f311354874a40ffb23453 631 Gene3D G3DSA:3.20.20.80 291 607 9.3E-38 T 29-03-2018 SMALA_RS16765 7760eb953f96189de13ad6c2ea881189 402 Pfam PF01385 Probable transposase 181 289 5.3E-18 T 29-03-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 SMALA_RS16765 7760eb953f96189de13ad6c2ea881189 402 Pfam PF07282 Putative transposase DNA-binding domain 324 393 6.7E-21 T 29-03-2018 IPR010095 Transposase IS605, OrfB, C-terminal SMALA_RS23795 34ece1e512f168df96df0c98211b876e 388 Gene3D G3DSA:2.40.10.10 145 276 9.4E-11 T 29-03-2018 SMALA_RS23795 34ece1e512f168df96df0c98211b876e 388 SUPERFAMILY SSF50494 132 349 2.46E-16 T 29-03-2018 IPR009003 Peptidase S1, PA clan SMALA_RS23795 34ece1e512f168df96df0c98211b876e 388 Gene3D G3DSA:2.40.10.10 277 384 5.7E-25 T 29-03-2018 SMALA_RS17580 7d11e5e0a292d5e61fb25e11b9bb6d4c 191 Gene3D G3DSA:2.60.60.30 19 186 1.8E-65 T 29-03-2018 SMALA_RS17580 7d11e5e0a292d5e61fb25e11b9bb6d4c 191 Pfam PF02342 TerD domain 1 187 3.3E-84 T 29-03-2018 IPR003325 TerD domain GO:0006950 SMALA_RS09810 b85638715ac6119d43b53c2fb2cf4de0 310 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 294 1.4E-48 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 SMALA_RS09810 b85638715ac6119d43b53c2fb2cf4de0 310 Gene3D G3DSA:1.10.3470.10 2 299 5.9E-50 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SMALA_RS19965 4e7a41ba135877fe172656d4062003d2 162 SUPERFAMILY SSF46785 18 77 6.59E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS19965 4e7a41ba135877fe172656d4062003d2 162 SUPERFAMILY SSF54909 81 155 5.77E-13 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel SMALA_RS19965 4e7a41ba135877fe172656d4062003d2 162 Gene3D G3DSA:3.30.70.920 71 161 2.2E-17 T 29-03-2018 SMALA_RS19965 4e7a41ba135877fe172656d4062003d2 162 Pfam PF01037 Lrp/AsnC ligand binding domain 90 155 1.0E-11 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain SMALA_RS19965 4e7a41ba135877fe172656d4062003d2 162 SMART SM00344 18 124 2.6E-21 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 SMALA_RS19965 4e7a41ba135877fe172656d4062003d2 162 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 18 34 5.1E-9 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMALA_RS19965 4e7a41ba135877fe172656d4062003d2 162 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 34 45 5.1E-9 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMALA_RS19965 4e7a41ba135877fe172656d4062003d2 162 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 45 64 5.1E-9 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMALA_RS19965 4e7a41ba135877fe172656d4062003d2 162 Gene3D G3DSA:1.10.10.10 14 69 2.3E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS19965 4e7a41ba135877fe172656d4062003d2 162 Pfam PF13412 Winged helix-turn-helix DNA-binding 18 65 2.0E-13 T 29-03-2018 SMALA_RS39985 c864d5937038d6ccb57706874d8d3862 185 SUPERFAMILY SSF50475 13 153 6.83E-21 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS39985 c864d5937038d6ccb57706874d8d3862 185 Gene3D G3DSA:2.30.110.10 5 166 8.7E-21 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS39985 c864d5937038d6ccb57706874d8d3862 185 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 13 144 1.4E-9 T 29-03-2018 IPR024747 Pyridoxamine 5'-phosphate oxidase-related SMALA_RS39455 371f63698366e849426107b1deb7b662 302 SUPERFAMILY SSF53474 25 299 4.72E-32 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS39455 371f63698366e849426107b1deb7b662 302 Gene3D G3DSA:3.40.50.1820 23 300 7.0E-28 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS39455 371f63698366e849426107b1deb7b662 302 Pfam PF00561 alpha/beta hydrolase fold 41 285 3.6E-13 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS02350 fe2d240ecbd4bc7cd627480ffcbf6290 2194 Gene3D G3DSA:3.40.47.10 26 296 2.0E-87 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS02350 fe2d240ecbd4bc7cd627480ffcbf6290 2194 Gene3D G3DSA:1.10.1200.10 2008 2110 6.1E-20 T 29-03-2018 SMALA_RS02350 fe2d240ecbd4bc7cd627480ffcbf6290 2194 SUPERFAMILY SSF47336 2022 2111 7.2E-23 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS02350 fe2d240ecbd4bc7cd627480ffcbf6290 2194 SMART SM00823 Phosphopantetheine attachment site 2030 2102 1.8E-30 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS02350 fe2d240ecbd4bc7cd627480ffcbf6290 2194 SMART SM00826 939 1106 2.5E-81 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS02350 fe2d240ecbd4bc7cd627480ffcbf6290 2194 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 412 531 2.1E-9 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS02350 fe2d240ecbd4bc7cd627480ffcbf6290 2194 Pfam PF08659 KR domain 1745 1923 1.9E-58 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS02350 fe2d240ecbd4bc7cd627480ffcbf6290 2194 SUPERFAMILY SSF51735 1742 1981 2.23E-43 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS02350 fe2d240ecbd4bc7cd627480ffcbf6290 2194 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2057 2072 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS02350 fe2d240ecbd4bc7cd627480ffcbf6290 2194 Pfam PF08990 Erythronolide synthase docking 3 27 7.1E-12 T 29-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 SMALA_RS02350 fe2d240ecbd4bc7cd627480ffcbf6290 2194 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1745 1925 3.2E-58 T 29-03-2018 SMALA_RS02350 fe2d240ecbd4bc7cd627480ffcbf6290 2194 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 284 3.5E-90 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS02350 fe2d240ecbd4bc7cd627480ffcbf6290 2194 Gene3D G3DSA:3.40.366.10 755 877 2.7E-23 T 29-03-2018 SMALA_RS02350 fe2d240ecbd4bc7cd627480ffcbf6290 2194 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 572 871 4.3E-109 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SMALA_RS02350 fe2d240ecbd4bc7cd627480ffcbf6290 2194 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 1557 1578 - T 29-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 SMALA_RS02350 fe2d240ecbd4bc7cd627480ffcbf6290 2194 SUPERFAMILY SSF50129 1444 1562 4.56E-28 T 29-03-2018 IPR011032 GroES-like SMALA_RS02350 fe2d240ecbd4bc7cd627480ffcbf6290 2194 Gene3D G3DSA:3.10.129.10 938 1065 8.7E-8 T 29-03-2018 SMALA_RS02350 fe2d240ecbd4bc7cd627480ffcbf6290 2194 Gene3D G3DSA:3.40.50.720 1738 2003 1.9E-48 T 29-03-2018 SMALA_RS02350 fe2d240ecbd4bc7cd627480ffcbf6290 2194 SMART SM00825 Beta-ketoacyl synthase 36 462 1.7E-222 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS02350 fe2d240ecbd4bc7cd627480ffcbf6290 2194 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 292 409 2.3E-42 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS02350 fe2d240ecbd4bc7cd627480ffcbf6290 2194 SMART SM00829 1430 1735 3.9E-176 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS02350 fe2d240ecbd4bc7cd627480ffcbf6290 2194 Pfam PF14765 Polyketide synthase dehydratase 939 1216 4.9E-56 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS02350 fe2d240ecbd4bc7cd627480ffcbf6290 2194 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 1450 1505 3.6E-6 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS02350 fe2d240ecbd4bc7cd627480ffcbf6290 2194 Gene3D G3DSA:3.90.180.10 1415 1737 8.6E-61 T 29-03-2018 SMALA_RS02350 fe2d240ecbd4bc7cd627480ffcbf6290 2194 SUPERFAMILY SSF55048 696 761 4.32E-12 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMALA_RS02350 fe2d240ecbd4bc7cd627480ffcbf6290 2194 Gene3D G3DSA:3.30.70.250 704 754 4.2E-15 T 29-03-2018 SMALA_RS02350 fe2d240ecbd4bc7cd627480ffcbf6290 2194 Gene3D G3DSA:3.40.366.10 568 703 4.2E-36 T 29-03-2018 SMALA_RS02350 fe2d240ecbd4bc7cd627480ffcbf6290 2194 Pfam PF00550 Phosphopantetheine attachment site 2032 2098 8.2E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS02350 fe2d240ecbd4bc7cd627480ffcbf6290 2194 SUPERFAMILY SSF51735 1529 1706 1.27E-39 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS02350 fe2d240ecbd4bc7cd627480ffcbf6290 2194 SUPERFAMILY SSF51735 1227 1408 5.12E-27 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS02350 fe2d240ecbd4bc7cd627480ffcbf6290 2194 SUPERFAMILY SSF52151 762 855 1.23E-62 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS02350 fe2d240ecbd4bc7cd627480ffcbf6290 2194 SUPERFAMILY SSF52151 568 697 1.23E-62 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS02350 fe2d240ecbd4bc7cd627480ffcbf6290 2194 SMART SM01294 2031 2098 1.3E-5 T 29-03-2018 SMALA_RS02350 fe2d240ecbd4bc7cd627480ffcbf6290 2194 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 197 213 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS02350 fe2d240ecbd4bc7cd627480ffcbf6290 2194 SUPERFAMILY SSF53901 30 399 1.59E-101 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS02350 fe2d240ecbd4bc7cd627480ffcbf6290 2194 Gene3D G3DSA:3.40.47.10 299 460 2.3E-59 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS02350 fe2d240ecbd4bc7cd627480ffcbf6290 2194 Pfam PF00107 Zinc-binding dehydrogenase 1568 1659 6.8E-16 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMALA_RS02350 fe2d240ecbd4bc7cd627480ffcbf6290 2194 Pfam PF00698 Acyl transferase domain 571 889 3.6E-82 T 29-03-2018 IPR014043 Acyl transferase SMALA_RS10025 ebe11b9398a586b9ab06c740bbad4b68 288 SMART SM00382 41 231 7.7E-18 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS10025 ebe11b9398a586b9ab06c740bbad4b68 288 Gene3D G3DSA:3.40.50.300 2 251 3.1E-59 T 29-03-2018 SMALA_RS10025 ebe11b9398a586b9ab06c740bbad4b68 288 SUPERFAMILY SSF52540 17 245 2.56E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS10025 ebe11b9398a586b9ab06c740bbad4b68 288 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS10025 ebe11b9398a586b9ab06c740bbad4b68 288 Pfam PF00005 ABC transporter 33 181 1.4E-26 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS40430 6fbd2441408b918246c1732c75e91c97 697 Pfam PF01968 Hydantoinase/oxoprolinase 200 486 1.6E-90 T 29-03-2018 IPR002821 Hydantoinase/oxoprolinase GO:0016787 Reactome: R-HSA-174403 SMALA_RS40430 6fbd2441408b918246c1732c75e91c97 697 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 5 179 7.9E-44 T 29-03-2018 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403 SMALA_RS40430 6fbd2441408b918246c1732c75e91c97 697 Gene3D G3DSA:3.40.50.2000 360 609 0.0026 T 29-03-2018 SMALA_RS40430 6fbd2441408b918246c1732c75e91c97 697 Gene3D G3DSA:3.30.420.40 4 309 1.1E-6 T 29-03-2018 SMALA_RS19120 8aeee755526d53b739a7112a8cf88893 292 SUPERFAMILY SSF51679 10 274 8.51E-36 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS19120 8aeee755526d53b739a7112a8cf88893 292 Gene3D G3DSA:3.20.20.30 18 288 1.5E-26 T 29-03-2018 SMALA_RS19120 8aeee755526d53b739a7112a8cf88893 292 TIGRFAM TIGR03620 F420_MSMEG_4141: probable F420-dependent oxidoreductase, MSMEG_4141 family 7 287 1.0E-113 T 29-03-2018 IPR019922 Luciferase-like, F420-dependent oxidoreductase, MSMEG4141, predicted SMALA_RS19120 8aeee755526d53b739a7112a8cf88893 292 Pfam PF00296 Luciferase-like monooxygenase 22 125 2.6E-11 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS40905 355ee834635bd20e47dcdf992b6f7b9d 316 Pfam PF13732 Domain of unknown function (DUF4162) 217 307 1.2E-7 T 29-03-2018 IPR025302 Domain of unknown function DUF4162 SMALA_RS40905 355ee834635bd20e47dcdf992b6f7b9d 316 Pfam PF00005 ABC transporter 20 163 2.1E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS40905 355ee834635bd20e47dcdf992b6f7b9d 316 Gene3D G3DSA:3.40.50.300 1 287 6.6E-69 T 29-03-2018 SMALA_RS40905 355ee834635bd20e47dcdf992b6f7b9d 316 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 12 309 1.1E-103 T 29-03-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 SMALA_RS40905 355ee834635bd20e47dcdf992b6f7b9d 316 SMART SM00382 29 220 1.1E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS40905 355ee834635bd20e47dcdf992b6f7b9d 316 SUPERFAMILY SSF52540 4 226 2.77E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS16695 bcbd0e167c2312f22e2d298cdfeba7c4 584 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 363 385 5.5E-5 T 29-03-2018 SMALA_RS16695 bcbd0e167c2312f22e2d298cdfeba7c4 584 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 5.5E-5 T 29-03-2018 SMALA_RS16695 bcbd0e167c2312f22e2d298cdfeba7c4 584 Gene3D G3DSA:1.20.58.100 425 535 2.8E-37 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMALA_RS16695 bcbd0e167c2312f22e2d298cdfeba7c4 584 TIGRFAM TIGR01816 sdhA_forward: succinate dehydrogenase, flavoprotein subunit 4 584 2.4E-278 T 29-03-2018 IPR011281 Succinate dehydrogenase, flavoprotein subunit GO:0006099|GO:0016627|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMALA_RS16695 bcbd0e167c2312f22e2d298cdfeba7c4 584 Gene3D G3DSA:4.10.80.40 536 584 1.3E-19 T 29-03-2018 SMALA_RS16695 bcbd0e167c2312f22e2d298cdfeba7c4 584 SUPERFAMILY SSF56425 236 355 3.44E-43 T 29-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMALA_RS16695 bcbd0e167c2312f22e2d298cdfeba7c4 584 Gene3D G3DSA:3.50.50.60 305 416 1.0E-21 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS16695 bcbd0e167c2312f22e2d298cdfeba7c4 584 SUPERFAMILY SSF46977 446 584 5.89E-51 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMALA_RS16695 bcbd0e167c2312f22e2d298cdfeba7c4 584 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 40 49 - T 29-03-2018 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMALA_RS16695 bcbd0e167c2312f22e2d298cdfeba7c4 584 Pfam PF02910 Fumarate reductase flavoprotein C-term 454 584 8.3E-47 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMALA_RS16695 bcbd0e167c2312f22e2d298cdfeba7c4 584 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 7 584 1.9E-248 T 29-03-2018 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMALA_RS16695 bcbd0e167c2312f22e2d298cdfeba7c4 584 SUPERFAMILY SSF51905 2 259 1.01E-71 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS16695 bcbd0e167c2312f22e2d298cdfeba7c4 584 SUPERFAMILY SSF51905 358 426 1.01E-71 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS16695 bcbd0e167c2312f22e2d298cdfeba7c4 584 PIRSF PIRSF000171 1 578 4.4E-50 T 29-03-2018 SMALA_RS16695 bcbd0e167c2312f22e2d298cdfeba7c4 584 Pfam PF00890 FAD binding domain 7 400 2.2E-115 T 29-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMALA_RS16695 bcbd0e167c2312f22e2d298cdfeba7c4 584 Gene3D G3DSA:3.50.50.60 3 292 5.2E-44 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS14015 8ad67b9b318996c8933d198cc61b196a 290 SUPERFAMILY SSF161098 13 290 2.09E-76 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS14015 8ad67b9b318996c8933d198cc61b196a 290 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 104 283 4.9E-20 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS14015 8ad67b9b318996c8933d198cc61b196a 290 Gene3D G3DSA:1.10.3720.10 7 277 6.8E-47 T 29-03-2018 SMALA_RS27325 779c78d489c05a6c4b2817edf26638d1 411 SUPERFAMILY SSF54897 47 116 6.23E-8 T 29-03-2018 IPR009020 Protease propeptides/proteinase inhibitor I9 SMALA_RS27325 779c78d489c05a6c4b2817edf26638d1 411 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 165 176 - T 29-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site SMALA_RS27325 779c78d489c05a6c4b2817edf26638d1 411 Gene3D G3DSA:3.30.70.80 45 104 2.0E-14 T 29-03-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 SMALA_RS27325 779c78d489c05a6c4b2817edf26638d1 411 Pfam PF05922 Peptidase inhibitor I9 71 117 9.0E-7 T 29-03-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 SMALA_RS27325 779c78d489c05a6c4b2817edf26638d1 411 SUPERFAMILY SSF52743 136 404 1.31E-69 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMALA_RS27325 779c78d489c05a6c4b2817edf26638d1 411 PRINTS PR00723 Subtilisin serine protease family (S8) signature 160 179 5.8E-20 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related SMALA_RS27325 779c78d489c05a6c4b2817edf26638d1 411 PRINTS PR00723 Subtilisin serine protease family (S8) signature 354 370 5.8E-20 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related SMALA_RS27325 779c78d489c05a6c4b2817edf26638d1 411 PRINTS PR00723 Subtilisin serine protease family (S8) signature 198 211 5.8E-20 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related SMALA_RS27325 779c78d489c05a6c4b2817edf26638d1 411 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 355 365 - T 29-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site SMALA_RS27325 779c78d489c05a6c4b2817edf26638d1 411 Pfam PF00082 Subtilase family 160 390 3.5E-35 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMALA_RS27325 779c78d489c05a6c4b2817edf26638d1 411 Gene3D G3DSA:3.40.50.200 105 406 4.1E-74 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMALA_RS42530 9987795403efb947732bff0788471497 411 Gene3D G3DSA:2.40.110.10 139 232 9.2E-16 T 29-03-2018 SMALA_RS42530 9987795403efb947732bff0788471497 411 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 252 386 4.9E-11 T 29-03-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain SMALA_RS42530 9987795403efb947732bff0788471497 411 SUPERFAMILY SSF56645 29 230 1.44E-37 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMALA_RS42530 9987795403efb947732bff0788471497 411 PIRSF PIRSF016578 12 409 7.6E-22 T 29-03-2018 SMALA_RS42530 9987795403efb947732bff0788471497 411 Gene3D G3DSA:1.10.540.10 19 138 1.3E-9 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS42530 9987795403efb947732bff0788471497 411 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 33 99 5.0E-5 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS42530 9987795403efb947732bff0788471497 411 Gene3D G3DSA:1.20.140.10 244 409 8.0E-17 T 29-03-2018 SMALA_RS42530 9987795403efb947732bff0788471497 411 SUPERFAMILY SSF47203 247 388 3.22E-15 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMALA_RS24960 722f44422f4c58dfea4c415c45164c2d 406 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 13 400 1.1E-120 T 29-03-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 SMALA_RS24960 722f44422f4c58dfea4c415c45164c2d 406 Gene3D G3DSA:3.90.226.10 148 243 2.5E-4 T 29-03-2018 SMALA_RS24960 722f44422f4c58dfea4c415c45164c2d 406 Pfam PF02601 Exonuclease VII, large subunit 318 398 1.6E-10 T 29-03-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 SMALA_RS24960 722f44422f4c58dfea4c415c45164c2d 406 Pfam PF02601 Exonuclease VII, large subunit 129 350 8.9E-61 T 29-03-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 SMALA_RS24960 722f44422f4c58dfea4c415c45164c2d 406 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 5 401 25.612 T 29-03-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 SMALA_RS24960 722f44422f4c58dfea4c415c45164c2d 406 Gene3D G3DSA:2.40.50.140 25 111 3.7E-5 T 29-03-2018 SMALA_RS24960 722f44422f4c58dfea4c415c45164c2d 406 Pfam PF13742 OB-fold nucleic acid binding domain 12 105 9.0E-18 T 29-03-2018 IPR025824 OB-fold nucleic acid binding domain GO:0003676 SMALA_RS40675 e7ce82feaa0ac046fabc56ef1bed180e 319 Pfam PF04909 Amidohydrolase 42 312 2.0E-34 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 SMALA_RS40675 e7ce82feaa0ac046fabc56ef1bed180e 319 Gene3D G3DSA:3.20.20.140 2 315 4.3E-45 T 29-03-2018 SMALA_RS40675 e7ce82feaa0ac046fabc56ef1bed180e 319 SUPERFAMILY SSF51556 37 313 1.17E-61 T 29-03-2018 IPR032466 Metal-dependent hydrolase SMALA_RS40860 7b7960e893569bfa8d7fbe709c9a6e25 368 Gene3D G3DSA:3.30.70.360 180 276 2.9E-25 T 29-03-2018 SMALA_RS40860 7b7960e893569bfa8d7fbe709c9a6e25 368 SUPERFAMILY SSF55031 176 274 1.33E-22 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain SMALA_RS40860 7b7960e893569bfa8d7fbe709c9a6e25 368 Pfam PF07687 Peptidase dimerisation domain 174 273 1.1E-18 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain SMALA_RS40860 7b7960e893569bfa8d7fbe709c9a6e25 368 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 105 143 - T 29-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 SMALA_RS40860 7b7960e893569bfa8d7fbe709c9a6e25 368 SUPERFAMILY SSF53187 9 176 6.86E-47 T 29-03-2018 SMALA_RS40860 7b7960e893569bfa8d7fbe709c9a6e25 368 SUPERFAMILY SSF53187 285 368 6.86E-47 T 29-03-2018 SMALA_RS40860 7b7960e893569bfa8d7fbe709c9a6e25 368 Gene3D G3DSA:3.40.630.10 5 179 1.1E-34 T 29-03-2018 SMALA_RS40860 7b7960e893569bfa8d7fbe709c9a6e25 368 Pfam PF01546 Peptidase family M20/M25/M40 72 366 8.2E-29 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 SMALA_RS10730 597b4f04e1e59e5bf2902d2b70177787 226 Pfam PF13829 Domain of unknown function (DUF4191) 8 224 2.9E-83 T 29-03-2018 IPR025445 Protein of unknown function DUF4191 SMALA_RS10730 597b4f04e1e59e5bf2902d2b70177787 226 ProDom PD037701 MEMBRANE INTEGRAL TRANSMEMBRANE RV2219/MT2276 NARROWLY PROBABLE PRECURSOR SIGNAL MLCB22.21 1 211 1.0E-83 T 29-03-2018 SMALA_RS14830 e0077cbeb275260f3dce9b2fd9a29c07 186 Gene3D G3DSA:1.10.10.10 1 87 6.0E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS14830 e0077cbeb275260f3dce9b2fd9a29c07 186 Pfam PF10400 Virulence activator alpha C-term 90 170 1.6E-10 T 29-03-2018 IPR018309 Transcription regulator PadR, C-terminal SMALA_RS14830 e0077cbeb275260f3dce9b2fd9a29c07 186 Pfam PF03551 Transcriptional regulator PadR-like family 7 79 8.6E-13 T 29-03-2018 IPR005149 Transcription regulator PadR, N-terminal SMALA_RS14830 e0077cbeb275260f3dce9b2fd9a29c07 186 SUPERFAMILY SSF46785 2 172 2.85E-34 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS18620 418611357021d0728341ae7ec93e9bf4 400 Gene3D G3DSA:2.40.10.10 279 385 1.7E-17 T 29-03-2018 SMALA_RS18620 418611357021d0728341ae7ec93e9bf4 400 SUPERFAMILY SSF50494 197 384 1.24E-35 T 29-03-2018 IPR009003 Peptidase S1, PA clan SMALA_RS18620 418611357021d0728341ae7ec93e9bf4 400 Pfam PF13365 Trypsin-like peptidase domain 221 359 1.1E-21 T 29-03-2018 SMALA_RS18620 418611357021d0728341ae7ec93e9bf4 400 Pfam PF02674 Colicin V production protein 4 146 9.4E-19 T 29-03-2018 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 SMALA_RS18620 418611357021d0728341ae7ec93e9bf4 400 Gene3D G3DSA:2.40.10.10 181 278 4.1E-16 T 29-03-2018 SMALA_RS18620 418611357021d0728341ae7ec93e9bf4 400 PRINTS PR00834 HtrA/DegQ protease family signature 251 271 1.3E-9 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMALA_RS18620 418611357021d0728341ae7ec93e9bf4 400 PRINTS PR00834 HtrA/DegQ protease family signature 229 241 1.3E-9 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMALA_RS18620 418611357021d0728341ae7ec93e9bf4 400 PRINTS PR00834 HtrA/DegQ protease family signature 330 347 1.3E-9 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMALA_RS18620 418611357021d0728341ae7ec93e9bf4 400 PRINTS PR00834 HtrA/DegQ protease family signature 290 314 1.3E-9 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMALA_RS00535 dfe14b8238d1b7682484a3257edda792 375 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 91 105 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 SMALA_RS00535 dfe14b8238d1b7682484a3257edda792 375 Pfam PF00107 Zinc-binding dehydrogenase 206 334 9.3E-26 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMALA_RS00535 dfe14b8238d1b7682484a3257edda792 375 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 58 164 3.9E-27 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS00535 dfe14b8238d1b7682484a3257edda792 375 SUPERFAMILY SSF51735 169 340 8.2E-40 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS00535 dfe14b8238d1b7682484a3257edda792 375 SUPERFAMILY SSF50129 30 203 2.28E-45 T 29-03-2018 IPR011032 GroES-like SMALA_RS00535 dfe14b8238d1b7682484a3257edda792 375 Gene3D G3DSA:3.40.50.720 194 342 1.0E-23 T 29-03-2018 SMALA_RS00535 dfe14b8238d1b7682484a3257edda792 375 Gene3D G3DSA:3.90.180.10 18 193 5.5E-49 T 29-03-2018 SMALA_RS00535 dfe14b8238d1b7682484a3257edda792 375 SMART SM00829 43 373 1.8E-5 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS24530 e746edce7471938672bfe383156bfbac 916 Gene3D G3DSA:2.130.10.10 83 250 3.6E-19 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMALA_RS24530 e746edce7471938672bfe383156bfbac 916 Gene3D G3DSA:2.130.10.10 251 449 1.0E-15 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMALA_RS24530 e746edce7471938672bfe383156bfbac 916 SUPERFAMILY SSF50969 84 401 1.18E-23 T 29-03-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like SMALA_RS24530 e746edce7471938672bfe383156bfbac 916 Pfam PF04185 Phosphoesterase family 510 777 4.1E-6 T 29-03-2018 IPR007312 Phosphoesterase GO:0016788 SMALA_RS24530 e746edce7471938672bfe383156bfbac 916 Gene3D G3DSA:3.40.720.10 477 787 9.3E-17 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 SMALA_RS24530 e746edce7471938672bfe383156bfbac 916 SUPERFAMILY SSF53649 699 802 5.23E-5 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 SMALA_RS07680 1f90a9822d3d80af07649b6c9df710e5 447 Gene3D G3DSA:3.30.450.90 91 194 5.1E-19 T 29-03-2018 SMALA_RS07680 1f90a9822d3d80af07649b6c9df710e5 447 Pfam PF00437 Type II/IV secretion system protein 96 370 1.1E-46 T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 SMALA_RS07680 1f90a9822d3d80af07649b6c9df710e5 447 SUPERFAMILY SSF52540 84 350 3.64E-38 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS07680 1f90a9822d3d80af07649b6c9df710e5 447 Gene3D G3DSA:3.40.50.300 195 409 4.5E-10 T 29-03-2018 SMALA_RS33125 8e6293ac0b42ddab8b92244becc438d9 188 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 9 185 9.3E-70 T 29-03-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 SMALA_RS33125 8e6293ac0b42ddab8b92244becc438d9 188 Gene3D G3DSA:3.40.50.300 84 187 8.2E-29 T 29-03-2018 SMALA_RS33125 8e6293ac0b42ddab8b92244becc438d9 188 ProSitePatterns PS00856 Guanylate kinase-like signature. 42 59 - T 29-03-2018 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 SMALA_RS33125 8e6293ac0b42ddab8b92244becc438d9 188 SUPERFAMILY SSF52540 7 185 5.63E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS33125 8e6293ac0b42ddab8b92244becc438d9 188 Pfam PF00625 Guanylate kinase 8 185 1.8E-43 T 29-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit SMALA_RS33125 8e6293ac0b42ddab8b92244becc438d9 188 Gene3D G3DSA:3.30.63.10 39 83 9.3E-24 T 29-03-2018 SMALA_RS33125 8e6293ac0b42ddab8b92244becc438d9 188 SMART SM00072 7 188 2.0E-61 T 29-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit SMALA_RS33125 8e6293ac0b42ddab8b92244becc438d9 188 Gene3D G3DSA:3.40.50.300 2 31 0.0014 T 29-03-2018 SMALA_RS33125 8e6293ac0b42ddab8b92244becc438d9 188 Hamap MF_00328 Guanylate kinase [gmk]. 6 188 34.335 T 29-03-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 SMALA_RS27515 a1246a29fa1b1e92c43a72432123df1a 421 Gene3D G3DSA:3.40.640.10 37 273 4.1E-57 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS27515 a1246a29fa1b1e92c43a72432123df1a 421 Gene3D G3DSA:3.90.1150.10 274 416 1.1E-52 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS27515 a1246a29fa1b1e92c43a72432123df1a 421 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 222 238 - T 29-03-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 SMALA_RS27515 a1246a29fa1b1e92c43a72432123df1a 421 Pfam PF00464 Serine hydroxymethyltransferase 9 389 8.2E-165 T 29-03-2018 SMALA_RS27515 a1246a29fa1b1e92c43a72432123df1a 421 PIRSF PIRSF000412 1 415 3.9E-158 T 29-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 SMALA_RS27515 a1246a29fa1b1e92c43a72432123df1a 421 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 7 417 50.857 T 29-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 SMALA_RS27515 a1246a29fa1b1e92c43a72432123df1a 421 SUPERFAMILY SSF53383 4 418 1.22E-173 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS33905 0e0066c31ebea80d50f6eb26355c836f 374 SUPERFAMILY SSF53474 59 322 2.29E-32 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS33905 0e0066c31ebea80d50f6eb26355c836f 374 Gene3D G3DSA:3.40.50.1820 64 334 1.2E-31 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS33905 0e0066c31ebea80d50f6eb26355c836f 374 Pfam PF00561 alpha/beta hydrolase fold 98 184 1.0E-7 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS33905 0e0066c31ebea80d50f6eb26355c836f 374 PRINTS PR00111 Alpha/beta hydrolase fold signature 152 165 7.8E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS33905 0e0066c31ebea80d50f6eb26355c836f 374 PRINTS PR00111 Alpha/beta hydrolase fold signature 166 179 7.8E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS33905 0e0066c31ebea80d50f6eb26355c836f 374 PRINTS PR00111 Alpha/beta hydrolase fold signature 274 288 7.8E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS33905 0e0066c31ebea80d50f6eb26355c836f 374 PRINTS PR00111 Alpha/beta hydrolase fold signature 109 124 7.8E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS20640 8a84f00c2fa6cb65b3f75ade06c29b43 922 Gene3D G3DSA:3.60.40.10 538 789 3.9E-51 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS20640 8a84f00c2fa6cb65b3f75ade06c29b43 922 Pfam PF13185 GAF domain 440 532 7.1E-7 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS20640 8a84f00c2fa6cb65b3f75ade06c29b43 922 SUPERFAMILY SSF55781 406 542 2.09E-13 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS20640 8a84f00c2fa6cb65b3f75ade06c29b43 922 SUPERFAMILY SSF55785 214 318 1.74E-7 T 29-03-2018 IPR000014 PAS domain SMALA_RS20640 8a84f00c2fa6cb65b3f75ade06c29b43 922 Pfam PF17203 Single cache domain 3 44 172 7.2E-28 T 29-03-2018 IPR033463 Single cache domain 3 SMALA_RS20640 8a84f00c2fa6cb65b3f75ade06c29b43 922 SUPERFAMILY SSF103190 47 175 3.81E-34 T 29-03-2018 IPR029151 Periplasmic sensor domain-like SMALA_RS20640 8a84f00c2fa6cb65b3f75ade06c29b43 922 Pfam PF08448 PAS fold 225 321 4.6E-7 T 29-03-2018 IPR013656 PAS fold-4 SMALA_RS20640 8a84f00c2fa6cb65b3f75ade06c29b43 922 SMART SM00065 339 541 4.7E-8 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS20640 8a84f00c2fa6cb65b3f75ade06c29b43 922 SMART SM00331 559 786 3.8E-42 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS20640 8a84f00c2fa6cb65b3f75ade06c29b43 922 Gene3D G3DSA:3.30.450.40 342 537 3.7E-33 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS20640 8a84f00c2fa6cb65b3f75ade06c29b43 922 SUPERFAMILY SSF81606 573 785 5.75E-11 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS20640 8a84f00c2fa6cb65b3f75ade06c29b43 922 SUPERFAMILY SSF55874 826 908 7.83E-7 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS20640 8a84f00c2fa6cb65b3f75ade06c29b43 922 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 586 786 1.7E-56 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS20640 8a84f00c2fa6cb65b3f75ade06c29b43 922 Gene3D G3DSA:3.30.450.20 38 170 7.1E-24 T 29-03-2018 SMALA_RS20640 8a84f00c2fa6cb65b3f75ade06c29b43 922 Gene3D G3DSA:3.30.450.20 201 325 5.7E-13 T 29-03-2018 SMALA_RS20640 8a84f00c2fa6cb65b3f75ade06c29b43 922 Pfam PF13581 Histidine kinase-like ATPase domain 799 906 1.0E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS20640 8a84f00c2fa6cb65b3f75ade06c29b43 922 Gene3D G3DSA:3.30.565.10 793 919 5.4E-11 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS20640 8a84f00c2fa6cb65b3f75ade06c29b43 922 SMART SM00091 219 284 0.0052 T 29-03-2018 IPR000014 PAS domain SMALA_RS22850 20ce9fb1bcc6e8b6fd2bdd7a6a92ffc8 290 Gene3D G3DSA:3.20.20.100 14 290 6.6E-65 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS22850 20ce9fb1bcc6e8b6fd2bdd7a6a92ffc8 290 PRINTS PR00069 Aldo-keto reductase signature 222 246 3.4E-8 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMALA_RS22850 20ce9fb1bcc6e8b6fd2bdd7a6a92ffc8 290 PRINTS PR00069 Aldo-keto reductase signature 52 76 3.4E-8 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMALA_RS22850 20ce9fb1bcc6e8b6fd2bdd7a6a92ffc8 290 PRINTS PR00069 Aldo-keto reductase signature 117 135 3.4E-8 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMALA_RS22850 20ce9fb1bcc6e8b6fd2bdd7a6a92ffc8 290 PRINTS PR00069 Aldo-keto reductase signature 152 169 3.4E-8 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMALA_RS22850 20ce9fb1bcc6e8b6fd2bdd7a6a92ffc8 290 Pfam PF00248 Aldo/keto reductase family 24 288 1.1E-45 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS22850 20ce9fb1bcc6e8b6fd2bdd7a6a92ffc8 290 SUPERFAMILY SSF51430 17 288 1.7E-64 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS23145 709bbe75d0dcee356714918fcb696d64 255 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 229 1.7E-38 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 SMALA_RS23145 709bbe75d0dcee356714918fcb696d64 255 Gene3D G3DSA:3.90.226.10 2 234 8.7E-50 T 29-03-2018 SMALA_RS23145 709bbe75d0dcee356714918fcb696d64 255 SUPERFAMILY SSF52096 3 253 8.89E-51 T 29-03-2018 IPR029045 ClpP/crotonase-like domain SMALA_RS34700 4e9023103b51f1420ae84160b9968f69 457 SMART SM01091 357 434 2.6E-16 T 29-03-2018 IPR005170 Transporter-associated domain SMALA_RS34700 4e9023103b51f1420ae84160b9968f69 457 SUPERFAMILY SSF56176 362 440 9.82E-15 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SMALA_RS34700 4e9023103b51f1420ae84160b9968f69 457 SUPERFAMILY SSF54631 213 348 2.4E-28 T 29-03-2018 SMALA_RS34700 4e9023103b51f1420ae84160b9968f69 457 Pfam PF00571 CBS domain 219 273 6.0E-4 T 29-03-2018 IPR000644 CBS domain SMALA_RS34700 4e9023103b51f1420ae84160b9968f69 457 Pfam PF00571 CBS domain 283 335 9.5E-7 T 29-03-2018 IPR000644 CBS domain SMALA_RS34700 4e9023103b51f1420ae84160b9968f69 457 Gene3D G3DSA:3.30.465.10 343 433 5.1E-21 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SMALA_RS34700 4e9023103b51f1420ae84160b9968f69 457 Gene3D G3DSA:3.10.580.10 196 342 1.9E-32 T 29-03-2018 SMALA_RS34700 4e9023103b51f1420ae84160b9968f69 457 Pfam PF03471 Transporter associated domain 364 431 5.1E-15 T 29-03-2018 IPR005170 Transporter-associated domain SMALA_RS34700 4e9023103b51f1420ae84160b9968f69 457 Pfam PF01595 Domain of unknown function DUF21 10 201 5.3E-33 T 29-03-2018 IPR002550 Domain of unknown function DUF21 SMALA_RS31575 83b2b65957f18b6287582ba7c1982880 63 SUPERFAMILY SSF51905 11 49 3.24E-7 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS31575 83b2b65957f18b6287582ba7c1982880 63 Gene3D G3DSA:3.50.50.60 6 62 6.1E-12 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS31575 83b2b65957f18b6287582ba7c1982880 63 Pfam PF05199 GMC oxidoreductase 12 42 5.5E-9 T 29-03-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 SMALA_RS12050 da60bdc54ba525aa5cd6e4b3cf40d7e1 164 Pfam PF11343 Protein of unknown function (DUF3145) 6 162 2.9E-73 T 29-03-2018 IPR021491 Protein of unknown function DUF3145 SMALA_RS18890 cb23483d501f307182073f7c53236e4f 142 SUPERFAMILY SSF55874 28 127 1.03E-9 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS18890 cb23483d501f307182073f7c53236e4f 142 Pfam PF13581 Histidine kinase-like ATPase domain 22 129 6.4E-13 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS18890 cb23483d501f307182073f7c53236e4f 142 Gene3D G3DSA:3.30.565.10 7 141 8.3E-14 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS33535 beaf64e94ea0fda2a0dc1d8ae3c238da 324 SUPERFAMILY SSF51197 25 315 2.56E-63 T 29-03-2018 SMALA_RS33535 beaf64e94ea0fda2a0dc1d8ae3c238da 324 Gene3D G3DSA:3.60.130.10 14 317 1.8E-55 T 29-03-2018 SMALA_RS33535 beaf64e94ea0fda2a0dc1d8ae3c238da 324 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 28 312 2.5E-31 T 29-03-2018 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 SMALA_RS02220 51980f7caa2360141dc9553de29cd31b 390 SUPERFAMILY SSF52949 198 385 1.45E-13 T 29-03-2018 SMALA_RS02220 51980f7caa2360141dc9553de29cd31b 390 Gene3D G3DSA:3.40.220.10 190 389 1.3E-15 T 29-03-2018 SMALA_RS30900 5d37c96d33bf7c0f7b08001968f90111 612 SUPERFAMILY SSF51735 25 206 6.2E-48 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS30900 5d37c96d33bf7c0f7b08001968f90111 612 Gene3D G3DSA:1.10.1040.10 512 612 3.3E-32 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMALA_RS30900 5d37c96d33bf7c0f7b08001968f90111 612 Gene3D G3DSA:1.10.1040.10 206 307 1.3E-25 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMALA_RS30900 5d37c96d33bf7c0f7b08001968f90111 612 Gene3D G3DSA:3.40.50.720 3 205 1.7E-49 T 29-03-2018 SMALA_RS30900 5d37c96d33bf7c0f7b08001968f90111 612 Gene3D G3DSA:3.40.50.720 310 511 1.2E-45 T 29-03-2018 SMALA_RS30900 5d37c96d33bf7c0f7b08001968f90111 612 SUPERFAMILY SSF48179 513 610 7.4E-29 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMALA_RS30900 5d37c96d33bf7c0f7b08001968f90111 612 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 513 609 5.2E-33 T 29-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 SMALA_RS30900 5d37c96d33bf7c0f7b08001968f90111 612 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 207 303 2.8E-27 T 29-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 SMALA_RS30900 5d37c96d33bf7c0f7b08001968f90111 612 SUPERFAMILY SSF51735 329 510 1.36E-46 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS30900 5d37c96d33bf7c0f7b08001968f90111 612 SUPERFAMILY SSF48179 206 312 3.57E-26 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMALA_RS30900 5d37c96d33bf7c0f7b08001968f90111 612 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 26 204 2.3E-56 T 29-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 SMALA_RS30900 5d37c96d33bf7c0f7b08001968f90111 612 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 333 510 1.9E-55 T 29-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 SMALA_RS31705 a00e2e4ad6acf1f6b66f24e1a050c267 200 Gene3D G3DSA:1.10.357.10 64 197 7.8E-18 T 29-03-2018 SMALA_RS31705 a00e2e4ad6acf1f6b66f24e1a050c267 200 SUPERFAMILY SSF48498 83 195 3.4E-18 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS31705 a00e2e4ad6acf1f6b66f24e1a050c267 200 Gene3D G3DSA:1.10.10.60 6 63 1.6E-13 T 29-03-2018 SMALA_RS31705 a00e2e4ad6acf1f6b66f24e1a050c267 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 63 5.5E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS31705 a00e2e4ad6acf1f6b66f24e1a050c267 200 SUPERFAMILY SSF46689 11 76 8.72E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS26465 d8df88e5a9c6f14ea2754906479f3492 258 SUPERFAMILY SSF53335 10 167 2.24E-30 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS26465 d8df88e5a9c6f14ea2754906479f3492 258 Pfam PF13649 Methyltransferase domain 49 148 3.3E-16 T 29-03-2018 SMALA_RS26465 d8df88e5a9c6f14ea2754906479f3492 258 Gene3D G3DSA:3.40.50.150 9 258 5.1E-33 T 29-03-2018 SMALA_RS31025 0935afa3ecc42235d551e3adc9fff0b5 321 Gene3D G3DSA:3.20.20.30 4 321 1.0E-58 T 29-03-2018 SMALA_RS31025 0935afa3ecc42235d551e3adc9fff0b5 321 TIGRFAM TIGR03557 F420_G6P_family: F420-dependent oxidoreductase, G6PDH family 4 319 1.9E-141 T 29-03-2018 IPR019945 F420-dependent glucose-6-phosphate dehydrogenase-related SMALA_RS31025 0935afa3ecc42235d551e3adc9fff0b5 321 Pfam PF00296 Luciferase-like monooxygenase 5 293 2.1E-52 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS31025 0935afa3ecc42235d551e3adc9fff0b5 321 SUPERFAMILY SSF51679 2 319 7.85E-64 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS13135 1f9f6621b25ca078d28c54c3af3b9cab 1390 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 703 1103 1.2E-153 T 29-03-2018 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 SMALA_RS13135 1f9f6621b25ca078d28c54c3af3b9cab 1390 SMART SM00316 726 805 2.7E-5 T 29-03-2018 IPR022967 RNA-binding domain, S1 SMALA_RS13135 1f9f6621b25ca078d28c54c3af3b9cab 1390 Pfam PF10150 Ribonuclease E/G family 807 1076 4.0E-108 T 29-03-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 SMALA_RS13135 1f9f6621b25ca078d28c54c3af3b9cab 1390 SUPERFAMILY SSF50249 728 811 1.93E-14 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMALA_RS13135 1f9f6621b25ca078d28c54c3af3b9cab 1390 Gene3D G3DSA:2.40.50.140 721 810 9.3E-26 T 29-03-2018 SMALA_RS12140 c7d9491308cf78c23178d0ef67b8c2cf 515 SUPERFAMILY SSF51011 385 514 1.37E-38 T 29-03-2018 SMALA_RS12140 c7d9491308cf78c23178d0ef67b8c2cf 515 SMART SM00813 307 508 1.2E-84 T 29-03-2018 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 SMALA_RS12140 c7d9491308cf78c23178d0ef67b8c2cf 515 Pfam PF06964 Alpha-L-arabinofuranosidase C-terminal domain 307 508 4.3E-43 T 29-03-2018 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 SMALA_RS12140 c7d9491308cf78c23178d0ef67b8c2cf 515 Gene3D G3DSA:2.60.40.1180 389 515 1.5E-40 T 29-03-2018 SMALA_RS12140 c7d9491308cf78c23178d0ef67b8c2cf 515 SUPERFAMILY SSF51445 33 397 3.55E-109 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS12140 c7d9491308cf78c23178d0ef67b8c2cf 515 Gene3D G3DSA:3.20.20.80 34 388 8.2E-110 T 29-03-2018 SMALA_RS35730 f442d160813594c0f259c44bd3d0878f 299 Hamap MF_00653 Coenzyme PQQ synthesis protein B [pqqB]. 1 299 101.397 T 29-03-2018 IPR011842 Coenzyme PQQ biosynthesis protein B GO:0006810|GO:0018189 SMALA_RS35730 f442d160813594c0f259c44bd3d0878f 299 Pfam PF12706 Beta-lactamase superfamily domain 48 265 1.2E-27 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS35730 f442d160813594c0f259c44bd3d0878f 299 Gene3D G3DSA:3.60.15.10 1 299 1.4E-36 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS35730 f442d160813594c0f259c44bd3d0878f 299 SUPERFAMILY SSF56281 1 299 6.44E-37 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS40960 ea931295b64137ab73120d64e23547be 160 Gene3D G3DSA:3.10.129.10 1 155 1.1E-35 T 29-03-2018 SMALA_RS40960 ea931295b64137ab73120d64e23547be 160 SUPERFAMILY SSF54637 2 148 1.53E-24 T 29-03-2018 IPR029069 HotDog domain SMALA_RS40960 ea931295b64137ab73120d64e23547be 160 Pfam PF07977 FabA-like domain 13 142 9.2E-12 T 29-03-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 SMALA_RS40740 2f04b152ba3f029852a2bc35ea87a87f 415 Pfam PF01566 Natural resistance-associated macrophage protein 36 387 7.3E-115 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 SMALA_RS40740 2f04b152ba3f029852a2bc35ea87a87f 415 Hamap MF_00221 Divalent metal cation transporter MntH [mntH]. 1 413 33.44 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 SMALA_RS40740 2f04b152ba3f029852a2bc35ea87a87f 415 PRINTS PR00447 Natural resistance-associated macrophage protein signature 95 121 5.4E-33 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 SMALA_RS40740 2f04b152ba3f029852a2bc35ea87a87f 415 PRINTS PR00447 Natural resistance-associated macrophage protein signature 303 322 5.4E-33 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 SMALA_RS40740 2f04b152ba3f029852a2bc35ea87a87f 415 PRINTS PR00447 Natural resistance-associated macrophage protein signature 197 220 5.4E-33 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 SMALA_RS40740 2f04b152ba3f029852a2bc35ea87a87f 415 PRINTS PR00447 Natural resistance-associated macrophage protein signature 123 142 5.4E-33 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 SMALA_RS40740 2f04b152ba3f029852a2bc35ea87a87f 415 PRINTS PR00447 Natural resistance-associated macrophage protein signature 148 169 5.4E-33 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 SMALA_RS40740 2f04b152ba3f029852a2bc35ea87a87f 415 TIGRFAM TIGR01197 nramp: metal ion transporter, metal ion (Mn2+/Fe2+) transporter (Nramp) family 15 381 5.9E-95 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 SMALA_RS28950 b25ccfa2c7f6a8789e98c3321187538c 232 Pfam PF13523 Acetyltransferase (GNAT) domain 70 214 1.3E-47 T 29-03-2018 SMALA_RS28950 b25ccfa2c7f6a8789e98c3321187538c 232 SMART SM01006 65 113 2.9E-10 T 29-03-2018 IPR019432 Siderophore biosynthesis protein, conserved domain SMALA_RS28950 b25ccfa2c7f6a8789e98c3321187538c 232 Gene3D G3DSA:3.40.630.30 17 229 6.6E-23 T 29-03-2018 SMALA_RS28950 b25ccfa2c7f6a8789e98c3321187538c 232 SUPERFAMILY SSF55729 60 226 4.18E-45 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS01535 6092e569c5c6434f8a9301bb693a6832 373 Pfam PF13489 Methyltransferase domain 121 279 8.7E-21 T 29-03-2018 SMALA_RS01535 6092e569c5c6434f8a9301bb693a6832 373 Gene3D G3DSA:3.40.50.150 73 302 6.9E-23 T 29-03-2018 SMALA_RS01535 6092e569c5c6434f8a9301bb693a6832 373 SUPERFAMILY SSF53335 95 297 1.09E-30 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS13405 f1e0c340c64a0faaba692e1f02e625a0 1010 SUPERFAMILY SSF49785 884 1005 1.98E-19 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS13405 f1e0c340c64a0faaba692e1f02e625a0 1010 Pfam PF02838 Glycosyl hydrolase family 20, domain 2 55 200 1.5E-21 T 29-03-2018 IPR015882 Beta-hexosaminidase, bacteial type, N-terminal KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822 SMALA_RS13405 f1e0c340c64a0faaba692e1f02e625a0 1010 Gene3D G3DSA:2.60.120.260 875 1009 7.9E-26 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS13405 f1e0c340c64a0faaba692e1f02e625a0 1010 SUPERFAMILY SSF51445 204 508 7.26E-87 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS13405 f1e0c340c64a0faaba692e1f02e625a0 1010 Gene3D G3DSA:1.20.58.460 514 653 2.0E-49 T 29-03-2018 SMALA_RS13405 f1e0c340c64a0faaba692e1f02e625a0 1010 SUPERFAMILY SSF55545 55 201 2.09E-13 T 29-03-2018 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMALA_RS13405 f1e0c340c64a0faaba692e1f02e625a0 1010 SUPERFAMILY SSF140657 525 643 1.44E-18 T 29-03-2018 SMALA_RS13405 f1e0c340c64a0faaba692e1f02e625a0 1010 Pfam PF00754 F5/8 type C domain 888 1000 3.7E-19 T 29-03-2018 IPR000421 Coagulation factor 5/8 C-terminal domain SMALA_RS13405 f1e0c340c64a0faaba692e1f02e625a0 1010 Gene3D G3DSA:3.30.379.10 43 200 1.3E-19 T 29-03-2018 SMALA_RS13405 f1e0c340c64a0faaba692e1f02e625a0 1010 Pfam PF07555 beta-N-acetylglucosaminidase 206 513 1.9E-100 T 29-03-2018 IPR011496 Beta-N-acetylglucosaminidase MetaCyc: PWY-7437 SMALA_RS13405 f1e0c340c64a0faaba692e1f02e625a0 1010 Gene3D G3DSA:3.20.20.80 203 513 1.1E-108 T 29-03-2018 SMALA_RS35245 1264760a3718a49c0a949897fb430157 200 SMART SM00116 70 118 1.7E-14 T 29-03-2018 IPR000644 CBS domain SMALA_RS35245 1264760a3718a49c0a949897fb430157 200 SMART SM00116 13 61 2.4E-6 T 29-03-2018 IPR000644 CBS domain SMALA_RS35245 1264760a3718a49c0a949897fb430157 200 Gene3D G3DSA:3.10.580.10 60 192 3.3E-21 T 29-03-2018 SMALA_RS35245 1264760a3718a49c0a949897fb430157 200 Gene3D G3DSA:3.10.580.10 1 58 9.7E-13 T 29-03-2018 SMALA_RS35245 1264760a3718a49c0a949897fb430157 200 Pfam PF00571 CBS domain 7 56 6.7E-11 T 29-03-2018 IPR000644 CBS domain SMALA_RS35245 1264760a3718a49c0a949897fb430157 200 Pfam PF00571 CBS domain 63 117 5.8E-19 T 29-03-2018 IPR000644 CBS domain SMALA_RS35245 1264760a3718a49c0a949897fb430157 200 SUPERFAMILY SSF54631 1 119 6.1E-35 T 29-03-2018 SMALA_RS35245 1264760a3718a49c0a949897fb430157 200 Pfam PF04972 BON domain 121 188 7.5E-13 T 29-03-2018 IPR007055 BON domain SMALA_RS35245 1264760a3718a49c0a949897fb430157 200 PIRSF PIRSF036990 4 60 5.3E-14 T 29-03-2018 IPR017080 Uncharacterised conserved protein UCP036990, CBS, BON SMALA_RS35245 1264760a3718a49c0a949897fb430157 200 PIRSF PIRSF036990 57 198 4.1E-40 T 29-03-2018 IPR017080 Uncharacterised conserved protein UCP036990, CBS, BON SMALA_RS37645 e321a4c4e189f9e8138113ac4c259dd0 296 Pfam PF13622 Thioesterase-like superfamily 33 282 2.1E-63 T 29-03-2018 SMALA_RS37645 e321a4c4e189f9e8138113ac4c259dd0 296 SUPERFAMILY SSF54637 116 285 2.3E-52 T 29-03-2018 IPR029069 HotDog domain SMALA_RS37645 e321a4c4e189f9e8138113ac4c259dd0 296 Gene3D G3DSA:3.10.129.10 133 287 2.2E-50 T 29-03-2018 SMALA_RS37645 e321a4c4e189f9e8138113ac4c259dd0 296 SUPERFAMILY SSF54637 5 114 3.64E-42 T 29-03-2018 IPR029069 HotDog domain SMALA_RS37645 e321a4c4e189f9e8138113ac4c259dd0 296 Gene3D G3DSA:3.10.129.10 2 116 1.0E-45 T 29-03-2018 SMALA_RS39035 812e15c8f87fb7891d3767626a506df3 324 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 130 321 1.8E-44 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS39035 812e15c8f87fb7891d3767626a506df3 324 Gene3D G3DSA:1.10.3720.10 14 310 2.5E-47 T 29-03-2018 SMALA_RS39035 812e15c8f87fb7891d3767626a506df3 324 SUPERFAMILY SSF161098 108 307 4.97E-22 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS19085 70418b7465ce2b8c0b277d44ff874408 283 SUPERFAMILY SSF101874 106 277 1.57E-49 T 29-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like SMALA_RS19085 70418b7465ce2b8c0b277d44ff874408 283 Gene3D G3DSA:2.40.128.110 104 281 9.0E-53 T 29-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like SMALA_RS19085 70418b7465ce2b8c0b277d44ff874408 283 Pfam PF04264 YceI-like domain 108 274 2.4E-38 T 29-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like SMALA_RS19085 70418b7465ce2b8c0b277d44ff874408 283 SMART SM00867 107 275 5.2E-63 T 29-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like SMALA_RS19085 70418b7465ce2b8c0b277d44ff874408 283 SUPERFAMILY SSF49452 10 91 1.96E-6 T 29-03-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 SMALA_RS19085 70418b7465ce2b8c0b277d44ff874408 283 Gene3D G3DSA:2.60.40.1120 13 101 1.7E-7 T 29-03-2018 SMALA_RS39860 57b521c1719b51de11122245b145b676 401 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 247 377 8.6E-22 T 29-03-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain SMALA_RS39860 57b521c1719b51de11122245b145b676 401 Gene3D G3DSA:1.10.540.10 13 119 1.3E-8 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS39860 57b521c1719b51de11122245b145b676 401 Gene3D G3DSA:2.40.110.10 121 206 5.3E-14 T 29-03-2018 SMALA_RS39860 57b521c1719b51de11122245b145b676 401 SUPERFAMILY SSF47203 241 375 1.93E-10 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMALA_RS39860 57b521c1719b51de11122245b145b676 401 Gene3D G3DSA:1.20.140.10 207 377 1.5E-16 T 29-03-2018 SMALA_RS39860 57b521c1719b51de11122245b145b676 401 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 24 99 2.0E-4 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS39860 57b521c1719b51de11122245b145b676 401 SUPERFAMILY SSF56645 24 215 4.06E-29 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMALA_RS39860 57b521c1719b51de11122245b145b676 401 PIRSF PIRSF016578 3 400 9.5E-116 T 29-03-2018 SMALA_RS19450 c2ec87381f6c05063d6adbb3382cd5e4 587 Pfam PF01964 Radical SAM ThiC family 128 548 1.6E-199 T 29-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 SMALA_RS19450 c2ec87381f6c05063d6adbb3382cd5e4 587 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 127 554 55.848 T 29-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 SMALA_RS19450 c2ec87381f6c05063d6adbb3382cd5e4 587 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 127 551 2.2E-212 T 29-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 SMALA_RS19450 c2ec87381f6c05063d6adbb3382cd5e4 587 Pfam PF13667 ThiC-associated domain 18 81 1.9E-21 T 29-03-2018 IPR025747 ThiC-associated domain KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 SMALA_RS13100 3dcb16b4ec6c1cab9d5e671e39e16126 432 Gene3D G3DSA:3.40.605.10 249 432 1.6E-38 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS13100 3dcb16b4ec6c1cab9d5e671e39e16126 432 SUPERFAMILY SSF53720 18 432 6.28E-117 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMALA_RS13100 3dcb16b4ec6c1cab9d5e671e39e16126 432 PIRSF PIRSF000151 14 432 1.4E-174 T 29-03-2018 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 SMALA_RS13100 3dcb16b4ec6c1cab9d5e671e39e16126 432 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 26 422 4.1E-155 T 29-03-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 SMALA_RS13100 3dcb16b4ec6c1cab9d5e671e39e16126 432 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 339 360 - T 29-03-2018 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 SMALA_RS13100 3dcb16b4ec6c1cab9d5e671e39e16126 432 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 17 432 42.552 T 29-03-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 SMALA_RS13100 3dcb16b4ec6c1cab9d5e671e39e16126 432 Gene3D G3DSA:3.40.605.10 12 248 1.7E-48 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS13100 3dcb16b4ec6c1cab9d5e671e39e16126 432 Pfam PF00171 Aldehyde dehydrogenase family 20 319 5.7E-22 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS04220 358def82632b952b15da1ef136bb18e2 310 Gene3D G3DSA:3.20.20.70 1 305 1.8E-86 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS04220 358def82632b952b15da1ef136bb18e2 310 SUPERFAMILY SSF51569 1 302 8.2E-65 T 29-03-2018 SMALA_RS04220 358def82632b952b15da1ef136bb18e2 310 Pfam PF00682 HMGL-like 5 284 1.4E-41 T 29-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 SMALA_RS33925 834ff3ff971663798b0616b1f9c102d5 317 TIGRFAM TIGR03215 ac_ald_DH_ac: acetaldehyde dehydrogenase (acetylating) 4 310 1.7E-138 T 29-03-2018 IPR003361 Acetaldehyde dehydrogenase GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 SMALA_RS33925 834ff3ff971663798b0616b1f9c102d5 317 SUPERFAMILY SSF51735 1 154 4.62E-28 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS33925 834ff3ff971663798b0616b1f9c102d5 317 SMART SM00859 6 122 6.3E-14 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 SMALA_RS33925 834ff3ff971663798b0616b1f9c102d5 317 PIRSF PIRSF015689 1 317 5.8E-130 T 29-03-2018 IPR003361 Acetaldehyde dehydrogenase GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 SMALA_RS33925 834ff3ff971663798b0616b1f9c102d5 317 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 6 119 2.1E-12 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 SMALA_RS33925 834ff3ff971663798b0616b1f9c102d5 317 Gene3D G3DSA:3.40.50.720 1 143 5.7E-13 T 29-03-2018 SMALA_RS33925 834ff3ff971663798b0616b1f9c102d5 317 Hamap MF_01657 Acetaldehyde dehydrogenase [mhpF]. 1 317 139.875 T 29-03-2018 IPR003361 Acetaldehyde dehydrogenase GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 SMALA_RS33925 834ff3ff971663798b0616b1f9c102d5 317 Gene3D G3DSA:3.30.360.10 144 286 1.2E-66 T 29-03-2018 SMALA_RS33925 834ff3ff971663798b0616b1f9c102d5 317 SUPERFAMILY SSF55347 130 286 3.07E-61 T 29-03-2018 SMALA_RS33925 834ff3ff971663798b0616b1f9c102d5 317 Pfam PF09290 Prokaryotic acetaldehyde dehydrogenase, dimerisation 130 286 2.6E-61 T 29-03-2018 IPR015426 Acetaldehyde dehydrogenase, C-terminal GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 SMALA_RS32490 4dab124714c8c57a7e63c36e2f97737c 456 SUPERFAMILY SSF52343 317 452 6.55E-29 T 29-03-2018 SMALA_RS32490 4dab124714c8c57a7e63c36e2f97737c 456 Gene3D G3DSA:2.40.30.10 229 326 1.1E-15 T 29-03-2018 SMALA_RS32490 4dab124714c8c57a7e63c36e2f97737c 456 Gene3D G3DSA:3.40.50.80 327 456 1.2E-22 T 29-03-2018 SMALA_RS32490 4dab124714c8c57a7e63c36e2f97737c 456 SUPERFAMILY SSF63380 231 327 2.33E-15 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 SMALA_RS32490 4dab124714c8c57a7e63c36e2f97737c 456 Pfam PF01794 Ferric reductase like transmembrane component 65 186 2.8E-16 T 29-03-2018 IPR013130 Ferric reductase transmembrane component-like domain SMALA_RS32490 4dab124714c8c57a7e63c36e2f97737c 456 PRINTS PR00410 Phenol hydroxylase reductase family signature 338 357 5.8E-8 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 SMALA_RS32490 4dab124714c8c57a7e63c36e2f97737c 456 PRINTS PR00410 Phenol hydroxylase reductase family signature 422 430 5.8E-8 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 SMALA_RS32490 4dab124714c8c57a7e63c36e2f97737c 456 PRINTS PR00410 Phenol hydroxylase reductase family signature 322 331 5.8E-8 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 SMALA_RS32490 4dab124714c8c57a7e63c36e2f97737c 456 Pfam PF00175 Oxidoreductase NAD-binding domain 339 435 7.6E-11 T 29-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 SMALA_RS26555 14196a1b5cfd9eb42b02aed7abec82ac 1249 SUPERFAMILY SSF48452 865 979 1.95E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS26555 14196a1b5cfd9eb42b02aed7abec82ac 1249 Gene3D G3DSA:1.20.5.50 97 244 1.3E-4 T 29-03-2018 SMALA_RS26555 14196a1b5cfd9eb42b02aed7abec82ac 1249 SUPERFAMILY SSF52540 456 658 4.61E-20 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS26555 14196a1b5cfd9eb42b02aed7abec82ac 1249 Gene3D G3DSA:1.10.10.10 1122 1201 1.2E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS26555 14196a1b5cfd9eb42b02aed7abec82ac 1249 Gene3D G3DSA:1.10.10.10 957 1042 5.5E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS26555 14196a1b5cfd9eb42b02aed7abec82ac 1249 Gene3D G3DSA:1.10.10.10 1049 1121 2.7E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS26555 14196a1b5cfd9eb42b02aed7abec82ac 1249 Gene3D G3DSA:1.10.10.10 1202 1241 0.095 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS26555 14196a1b5cfd9eb42b02aed7abec82ac 1249 Gene3D G3DSA:3.40.50.300 454 603 5.2E-18 T 29-03-2018 SMALA_RS26555 14196a1b5cfd9eb42b02aed7abec82ac 1249 Gene3D G3DSA:1.10.260.40 26 96 1.1E-5 T 29-03-2018 SMALA_RS19630 03b0aa6393c102590595a65b719a53df 496 TIGRFAM TIGR02692 tRNA_CCA_actino: CCA tRNA nucleotidyltransferase 23 491 1.0E-244 T 29-03-2018 IPR014065 tRNA adenylyltransferase SMALA_RS19630 03b0aa6393c102590595a65b719a53df 496 SMART SM00471 280 495 5.0E-5 T 29-03-2018 IPR003607 HD/PDEase domain SMALA_RS19630 03b0aa6393c102590595a65b719a53df 496 Pfam PF01966 HD domain 284 380 4.5E-14 T 29-03-2018 IPR006674 HD domain SMALA_RS19630 03b0aa6393c102590595a65b719a53df 496 Pfam PF01743 Poly A polymerase head domain 51 182 1.2E-29 T 29-03-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 SMALA_RS19630 03b0aa6393c102590595a65b719a53df 496 Gene3D G3DSA:3.30.460.10 28 180 3.8E-43 T 29-03-2018 SMALA_RS19630 03b0aa6393c102590595a65b719a53df 496 Gene3D G3DSA:1.10.3090.10 181 490 4.3E-76 T 29-03-2018 SMALA_RS19630 03b0aa6393c102590595a65b719a53df 496 SUPERFAMILY SSF81891 180 492 3.01E-71 T 29-03-2018 SMALA_RS19630 03b0aa6393c102590595a65b719a53df 496 SUPERFAMILY SSF81301 32 179 9.37E-34 T 29-03-2018 SMALA_RS19630 03b0aa6393c102590595a65b719a53df 496 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 209 270 6.4E-21 T 29-03-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 SMALA_RS19630 03b0aa6393c102590595a65b719a53df 496 TIGRFAM TIGR00277 HDIG: HDIG domain 281 357 5.7E-17 T 29-03-2018 IPR006675 HDIG domain SMALA_RS31410 4a9653431b309cee56224208bf31b99e 479 SUPERFAMILY SSF53649 425 468 2.62E-70 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 SMALA_RS31410 4a9653431b309cee56224208bf31b99e 479 SUPERFAMILY SSF53649 14 370 2.62E-70 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 SMALA_RS31410 4a9653431b309cee56224208bf31b99e 479 Gene3D G3DSA:3.30.1360.110 285 368 4.3E-20 T 29-03-2018 IPR023116 Phosphonoacetate hydrolase, insert domain KEGG: 00440+3.11.1.2 SMALA_RS31410 4a9653431b309cee56224208bf31b99e 479 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 19 384 4.6E-60 T 29-03-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 SMALA_RS31410 4a9653431b309cee56224208bf31b99e 479 Gene3D G3DSA:3.40.720.10 7 252 4.1E-8 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 SMALA_RS30470 f8128301747133b78820b06be188500c 571 Pfam PF01341 Glycosyl hydrolases family 6 345 527 4.0E-45 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMALA_RS30470 f8128301747133b78820b06be188500c 571 Pfam PF01341 Glycosyl hydrolases family 6 68 179 5.5E-26 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMALA_RS30470 f8128301747133b78820b06be188500c 571 SUPERFAMILY SSF51989 58 179 9.03E-27 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMALA_RS30470 f8128301747133b78820b06be188500c 571 SUPERFAMILY SSF51989 459 560 9.29E-49 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMALA_RS30470 f8128301747133b78820b06be188500c 571 SUPERFAMILY SSF51989 332 423 9.29E-49 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMALA_RS30470 f8128301747133b78820b06be188500c 571 PIRSF PIRSF001100 166 337 4000.0 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMALA_RS30470 f8128301747133b78820b06be188500c 571 PIRSF PIRSF001100 2 192 1.1E-27 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMALA_RS30470 f8128301747133b78820b06be188500c 571 PIRSF PIRSF001100 332 439 7.0E-17 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMALA_RS30470 f8128301747133b78820b06be188500c 571 PIRSF PIRSF001100 449 562 5.0E-28 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMALA_RS30470 f8128301747133b78820b06be188500c 571 PRINTS PR00733 Glycosyl hydrolase family 6 signature 66 85 5.4E-7 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMALA_RS30470 f8128301747133b78820b06be188500c 571 PRINTS PR00733 Glycosyl hydrolase family 6 signature 137 152 5.4E-7 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMALA_RS30470 f8128301747133b78820b06be188500c 571 PRINTS PR00733 Glycosyl hydrolase family 6 signature 109 122 5.4E-7 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMALA_RS30470 f8128301747133b78820b06be188500c 571 Gene3D G3DSA:3.20.20.40 41 203 1.5E-36 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMALA_RS30470 f8128301747133b78820b06be188500c 571 Gene3D G3DSA:3.20.20.40 327 562 2.4E-67 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMALA_RS30470 f8128301747133b78820b06be188500c 571 ProSitePatterns PS00656 Glycosyl hydrolases family 6 signature 2. 154 163 - T 29-03-2018 IPR001524 Glycoside hydrolase, family 6, conserved site GO:0004553|GO:0005975 SMALA_RS26240 ae69fa19b93dabb018a332ee696ab983 773 Gene3D G3DSA:1.20.5.510 713 768 0.0015 T 29-03-2018 SMALA_RS18115 a5268fb171fc69da8e547f0b33014cf4 680 Pfam PF01434 Peptidase family M41 406 611 3.3E-81 T 29-03-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 SMALA_RS18115 a5268fb171fc69da8e547f0b33014cf4 680 Gene3D G3DSA:3.40.50.300 145 352 8.5E-63 T 29-03-2018 SMALA_RS18115 a5268fb171fc69da8e547f0b33014cf4 680 ProSitePatterns PS00674 AAA-protein family signature. 312 330 - T 29-03-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 SMALA_RS18115 a5268fb171fc69da8e547f0b33014cf4 680 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 209 341 6.7E-45 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 SMALA_RS18115 a5268fb171fc69da8e547f0b33014cf4 680 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 122 612 1.5E-233 T 29-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 SMALA_RS18115 a5268fb171fc69da8e547f0b33014cf4 680 SMART SM00382 205 344 6.5E-25 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS18115 a5268fb171fc69da8e547f0b33014cf4 680 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 5 621 37.358 T 29-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 SMALA_RS18115 a5268fb171fc69da8e547f0b33014cf4 680 SUPERFAMILY SSF140990 423 618 8.5E-75 T 29-03-2018 SMALA_RS18115 a5268fb171fc69da8e547f0b33014cf4 680 Gene3D G3DSA:1.10.8.60 353 435 2.4E-21 T 29-03-2018 SMALA_RS18115 a5268fb171fc69da8e547f0b33014cf4 680 SUPERFAMILY SSF52540 163 413 6.63E-71 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS18085 c6c765cf489f7124086cf0e780911202 292 Gene3D G3DSA:3.20.20.20 11 292 8.7E-104 T 29-03-2018 SMALA_RS18085 c6c765cf489f7124086cf0e780911202 292 Pfam PF00809 Pterin binding enzyme 22 267 4.3E-83 T 29-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMALA_RS18085 c6c765cf489f7124086cf0e780911202 292 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 21 36 - T 29-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMALA_RS18085 c6c765cf489f7124086cf0e780911202 292 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 21 281 1.1E-89 T 29-03-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 SMALA_RS18085 c6c765cf489f7124086cf0e780911202 292 SUPERFAMILY SSF51717 19 282 1.31E-91 T 29-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMALA_RS18085 c6c765cf489f7124086cf0e780911202 292 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 55 68 - T 29-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMALA_RS06685 035811b9b56a6ef1c3e97e1d6fead881 294 Pfam PF03466 LysR substrate binding domain 82 288 3.5E-37 T 29-03-2018 IPR005119 LysR, substrate-binding SMALA_RS06685 035811b9b56a6ef1c3e97e1d6fead881 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 1 56 2.2E-19 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS06685 035811b9b56a6ef1c3e97e1d6fead881 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 34 1.0E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS06685 035811b9b56a6ef1c3e97e1d6fead881 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 45 1.0E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS06685 035811b9b56a6ef1c3e97e1d6fead881 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 13 24 1.0E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS06685 035811b9b56a6ef1c3e97e1d6fead881 294 Gene3D G3DSA:3.40.190.10 178 260 1.1E-20 T 29-03-2018 SMALA_RS06685 035811b9b56a6ef1c3e97e1d6fead881 294 Gene3D G3DSA:1.10.10.10 1 78 2.5E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS06685 035811b9b56a6ef1c3e97e1d6fead881 294 Gene3D G3DSA:3.40.190.10 83 177 1.7E-19 T 29-03-2018 SMALA_RS06685 035811b9b56a6ef1c3e97e1d6fead881 294 SUPERFAMILY SSF53850 82 290 1.25E-37 T 29-03-2018 SMALA_RS06685 035811b9b56a6ef1c3e97e1d6fead881 294 SUPERFAMILY SSF46785 2 78 1.54E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS21375 d721dbad85edf2d531cefed1f9a70bdb 408 Gene3D G3DSA:3.40.50.2300 22 161 1.4E-25 T 29-03-2018 SMALA_RS21375 d721dbad85edf2d531cefed1f9a70bdb 408 SMART SM00448 26 141 1.4E-5 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS21375 d721dbad85edf2d531cefed1f9a70bdb 408 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 212 407 4.1E-38 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS21375 d721dbad85edf2d531cefed1f9a70bdb 408 SMART SM00331 183 407 4.5E-16 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS21375 d721dbad85edf2d531cefed1f9a70bdb 408 SUPERFAMILY SSF52172 24 165 1.99E-15 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS21375 d721dbad85edf2d531cefed1f9a70bdb 408 Pfam PF00072 Response regulator receiver domain 29 129 6.0E-9 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS21375 d721dbad85edf2d531cefed1f9a70bdb 408 Gene3D G3DSA:3.60.40.10 162 408 1.8E-23 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS01170 321c7ac523fc2cbcf0ae877551a5cffd 303 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 51 294 5.9E-10 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMALA_RS01170 321c7ac523fc2cbcf0ae877551a5cffd 303 SUPERFAMILY SSF56219 46 298 1.18E-35 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMALA_RS01170 321c7ac523fc2cbcf0ae877551a5cffd 303 Gene3D G3DSA:3.60.10.10 43 303 9.2E-38 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMALA_RS04465 e9e2fe695c2cd6d026d88a518b14a907 362 Gene3D G3DSA:2.130.10.10 1 361 1.5E-71 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMALA_RS04465 e9e2fe695c2cd6d026d88a518b14a907 362 SUPERFAMILY SSF110296 4 360 9.02E-63 T 29-03-2018 SMALA_RS27420 f3298c583169713506219bfa1e587134 222 Gene3D G3DSA:3.40.50.1860 20 118 2.4E-8 T 29-03-2018 SMALA_RS27420 f3298c583169713506219bfa1e587134 222 Gene3D G3DSA:3.40.50.1860 119 208 2.7E-15 T 29-03-2018 SMALA_RS14570 2b143d58715b85336603e8d1b58a8bd3 406 Pfam PF04261 Dyp-type peroxidase family 50 394 5.6E-103 T 29-03-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 SMALA_RS14570 2b143d58715b85336603e8d1b58a8bd3 406 SUPERFAMILY SSF54909 44 400 6.97E-94 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel SMALA_RS14570 2b143d58715b85336603e8d1b58a8bd3 406 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 50 394 1.0E-94 T 29-03-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 SMALA_RS14570 2b143d58715b85336603e8d1b58a8bd3 406 TIGRFAM TIGR01412 tat_substr_1: Tat-translocated enzyme 4 405 2.1E-142 T 29-03-2018 IPR006313 Deferrochelatase/peroxidase EfeB GO:0004601|GO:0015684|GO:0020037|GO:0033212 SMALA_RS38325 3e6feb632c773b016933d01f94e16ff6 343 SUPERFAMILY SSF89372 6 204 9.81E-22 T 29-03-2018 SMALA_RS38325 3e6feb632c773b016933d01f94e16ff6 343 Gene3D G3DSA:2.120.10.70 2 106 4.7E-16 T 29-03-2018 SMALA_RS38325 3e6feb632c773b016933d01f94e16ff6 343 Gene3D G3DSA:2.120.10.70 107 257 2.0E-20 T 29-03-2018 SMALA_RS38325 3e6feb632c773b016933d01f94e16ff6 343 SUPERFAMILY SSF89372 153 331 7.59E-15 T 29-03-2018 SMALA_RS38325 3e6feb632c773b016933d01f94e16ff6 343 Gene3D G3DSA:2.120.10.70 262 342 2.1E-6 T 29-03-2018 SMALA_RS16505 e0d731448e3abcc100ab87173ec9e4f0 431 Gene3D G3DSA:1.10.3470.10 21 368 5.0E-47 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SMALA_RS16505 e0d731448e3abcc100ab87173ec9e4f0 431 Pfam PF02653 Branched-chain amino acid transport system / permease component 66 342 1.3E-32 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 SMALA_RS11960 5f3ea8d03bdeaac7a2f428181b1e556f 230 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 43 6.0E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS11960 5f3ea8d03bdeaac7a2f428181b1e556f 230 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 51 74 6.0E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS11960 5f3ea8d03bdeaac7a2f428181b1e556f 230 Gene3D G3DSA:1.10.357.10 75 219 2.1E-24 T 29-03-2018 SMALA_RS11960 5f3ea8d03bdeaac7a2f428181b1e556f 230 SUPERFAMILY SSF46689 17 88 8.21E-18 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS11960 5f3ea8d03bdeaac7a2f428181b1e556f 230 Pfam PF00440 Bacterial regulatory proteins, tetR family 30 74 1.8E-16 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS11960 5f3ea8d03bdeaac7a2f428181b1e556f 230 Gene3D G3DSA:1.10.10.60 1 74 9.2E-21 T 29-03-2018 SMALA_RS11960 5f3ea8d03bdeaac7a2f428181b1e556f 230 ProSitePatterns PS01081 TetR-type HTH domain signature. 42 72 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site SMALA_RS05675 9cfa52bd1b02be418f942de7394cf104 431 Gene3D G3DSA:3.40.50.1000 76 366 4.1E-8 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS05675 9cfa52bd1b02be418f942de7394cf104 431 SUPERFAMILY SSF56784 150 370 1.25E-9 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS05675 9cfa52bd1b02be418f942de7394cf104 431 SUPERFAMILY SSF56784 74 92 1.25E-9 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS10185 b0b212bb95d842f89771e553df9845ca 98 Pfam PF02325 YGGT family 10 90 7.7E-13 T 29-03-2018 IPR003425 CCB3/YggT GO:0016020 SMALA_RS37580 80c9d05319b27571fd48eb3742f26f17 390 SUPERFAMILY SSF51658 2 387 2.09E-115 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SMALA_RS37580 80c9d05319b27571fd48eb3742f26f17 390 TIGRFAM TIGR02631 xylA_Arthro: xylose isomerase 3 386 1.3E-222 T 29-03-2018 IPR013453 Xylose isomerase, actinobacteria GO:0009045|GO:0042732 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 SMALA_RS37580 80c9d05319b27571fd48eb3742f26f17 390 Gene3D G3DSA:3.20.20.150 6 388 7.7E-85 T 29-03-2018 SMALA_RS37580 80c9d05319b27571fd48eb3742f26f17 390 Hamap MF_00455 Xylose isomerase [xylA]. 1 385 37.936 T 29-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 SMALA_RS37580 80c9d05319b27571fd48eb3742f26f17 390 Pfam PF01261 Xylose isomerase-like TIM barrel 41 265 1.4E-26 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SMALA_RS37580 80c9d05319b27571fd48eb3742f26f17 390 PRINTS PR00688 Xylose isomerase signature 82 102 2.6E-74 T 29-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 SMALA_RS37580 80c9d05319b27571fd48eb3742f26f17 390 PRINTS PR00688 Xylose isomerase signature 105 124 2.6E-74 T 29-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 SMALA_RS37580 80c9d05319b27571fd48eb3742f26f17 390 PRINTS PR00688 Xylose isomerase signature 178 202 2.6E-74 T 29-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 SMALA_RS37580 80c9d05319b27571fd48eb3742f26f17 390 PRINTS PR00688 Xylose isomerase signature 281 292 2.6E-74 T 29-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 SMALA_RS37580 80c9d05319b27571fd48eb3742f26f17 390 PRINTS PR00688 Xylose isomerase signature 248 259 2.6E-74 T 29-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 SMALA_RS37580 80c9d05319b27571fd48eb3742f26f17 390 PRINTS PR00688 Xylose isomerase signature 45 67 2.6E-74 T 29-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 SMALA_RS37580 80c9d05319b27571fd48eb3742f26f17 390 PRINTS PR00688 Xylose isomerase signature 156 175 2.6E-74 T 29-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 SMALA_RS37580 80c9d05319b27571fd48eb3742f26f17 390 PRINTS PR00688 Xylose isomerase signature 220 247 2.6E-74 T 29-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 SMALA_RS37580 80c9d05319b27571fd48eb3742f26f17 390 PRINTS PR00688 Xylose isomerase signature 129 150 2.6E-74 T 29-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 SMALA_RS27040 0d1652d1f36c0168ef2b60d192be26f4 1335 Gene3D G3DSA:1.20.120.20 584 738 0.028 T 29-03-2018 SMALA_RS27040 0d1652d1f36c0168ef2b60d192be26f4 1335 Gene3D G3DSA:1.20.5.620 327 359 0.0062 T 29-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain SMALA_RS27040 0d1652d1f36c0168ef2b60d192be26f4 1335 Gene3D G3DSA:1.20.5.620 196 258 0.11 T 29-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain SMALA_RS27040 0d1652d1f36c0168ef2b60d192be26f4 1335 Gene3D G3DSA:1.20.5.620 267 326 0.0027 T 29-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain SMALA_RS27040 0d1652d1f36c0168ef2b60d192be26f4 1335 Gene3D G3DSA:1.20.5.620 1102 1200 0.014 T 29-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain SMALA_RS27040 0d1652d1f36c0168ef2b60d192be26f4 1335 Gene3D G3DSA:1.20.5.620 957 1034 0.22 T 29-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain SMALA_RS27040 0d1652d1f36c0168ef2b60d192be26f4 1335 Gene3D G3DSA:1.20.5.620 360 426 0.013 T 29-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain SMALA_RS27040 0d1652d1f36c0168ef2b60d192be26f4 1335 Gene3D G3DSA:1.20.5.620 1201 1281 0.084 T 29-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain SMALA_RS27040 0d1652d1f36c0168ef2b60d192be26f4 1335 Gene3D G3DSA:1.20.120.20 739 914 4.0E-6 T 29-03-2018 SMALA_RS27040 0d1652d1f36c0168ef2b60d192be26f4 1335 Gene3D G3DSA:1.20.120.20 431 583 1.5E-5 T 29-03-2018 SMALA_RS13615 8d6deacd46ca19139c00a52c3791b529 111 SUPERFAMILY SSF54913 6 103 1.56E-31 T 29-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta SMALA_RS13615 8d6deacd46ca19139c00a52c3791b529 111 Pfam PF02641 Uncharacterized ACR, COG1993 8 103 1.9E-36 T 29-03-2018 IPR003793 Domain of unknown function DUF190 SMALA_RS13615 8d6deacd46ca19139c00a52c3791b529 111 Gene3D G3DSA:3.30.70.120 1 111 2.0E-43 T 29-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal SMALA_RS23635 a4465db133d4965e1c8db58ca18200ac 443 SUPERFAMILY SSF55486 219 297 3.89E-5 T 29-03-2018 SMALA_RS23635 a4465db133d4965e1c8db58ca18200ac 443 TIGRFAM TIGR03296 M6dom_TIGR03296: M6 family metalloprotease domain 98 361 8.7E-46 T 29-03-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 SMALA_RS14910 4b619871845a36595086e5ecc4350171 384 Gene3D G3DSA:3.30.420.40 296 382 4.7E-11 T 29-03-2018 SMALA_RS14910 4b619871845a36595086e5ecc4350171 384 SUPERFAMILY SSF53067 166 378 2.65E-35 T 29-03-2018 SMALA_RS14910 4b619871845a36595086e5ecc4350171 384 Pfam PF00480 ROK family 166 290 6.8E-31 T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 SMALA_RS14910 4b619871845a36595086e5ecc4350171 384 Gene3D G3DSA:3.30.420.40 1 243 3.5E-27 T 29-03-2018 SMALA_RS14910 4b619871845a36595086e5ecc4350171 384 ProSitePatterns PS01125 ROK family signature. 241 268 - T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 SMALA_RS14910 4b619871845a36595086e5ecc4350171 384 Gene3D G3DSA:3.30.420.40 244 295 1.4E-17 T 29-03-2018 SMALA_RS18250 9f7fdde00cc33c9d9a812f95e53e54d8 302 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 55 63 3.3E-12 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 SMALA_RS18250 9f7fdde00cc33c9d9a812f95e53e54d8 302 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 100 115 3.3E-12 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 SMALA_RS18250 9f7fdde00cc33c9d9a812f95e53e54d8 302 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 139 155 3.3E-12 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 SMALA_RS18250 9f7fdde00cc33c9d9a812f95e53e54d8 302 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 8 164 12.309 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 SMALA_RS18250 9f7fdde00cc33c9d9a812f95e53e54d8 302 Pfam PF01252 Signal peptidase (SPase) II 17 157 2.3E-22 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 SMALA_RS43035 de04c998e4cf92ac863a23561a1fa5cd 340 PIRSF PIRSF028757 9 331 2.0E-51 T 29-03-2018 IPR003507 Peptidase family S66 SMALA_RS43035 de04c998e4cf92ac863a23561a1fa5cd 340 SUPERFAMILY SSF141986 181 322 2.88E-24 T 29-03-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain SMALA_RS43035 de04c998e4cf92ac863a23561a1fa5cd 340 Gene3D G3DSA:3.40.50.10740 5 169 1.5E-35 T 29-03-2018 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal domain SMALA_RS43035 de04c998e4cf92ac863a23561a1fa5cd 340 Gene3D G3DSA:3.50.30.60 173 334 9.4E-34 T 29-03-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain SMALA_RS43035 de04c998e4cf92ac863a23561a1fa5cd 340 Pfam PF02016 LD-carboxypeptidase 22 316 3.3E-54 T 29-03-2018 IPR003507 Peptidase family S66 SMALA_RS43035 de04c998e4cf92ac863a23561a1fa5cd 340 SUPERFAMILY SSF52317 9 151 2.84E-27 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS35480 29c31cab7b33c3a81fb85fe03e7d0d15 368 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 258 271 - T 29-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 SMALA_RS35480 29c31cab7b33c3a81fb85fe03e7d0d15 368 Pfam PF00294 pfkB family carbohydrate kinase 26 303 9.5E-35 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB SMALA_RS35480 29c31cab7b33c3a81fb85fe03e7d0d15 368 Gene3D G3DSA:3.40.1190.20 20 322 5.7E-58 T 29-03-2018 IPR029056 Ribokinase-like SMALA_RS35480 29c31cab7b33c3a81fb85fe03e7d0d15 368 SUPERFAMILY SSF53613 22 313 4.52E-54 T 29-03-2018 IPR029056 Ribokinase-like SMALA_RS07520 309677c57d0501b1959db8629123326c 795 Gene3D G3DSA:3.40.50.300 364 734 2.6E-24 T 29-03-2018 SMALA_RS07520 309677c57d0501b1959db8629123326c 795 Pfam PF10412 Type IV secretion-system coupling protein DNA-binding domain 403 474 1.1E-6 T 29-03-2018 IPR019476 Type IV secretion system coupling protein TraD, DNA-binding domain SMALA_RS07520 309677c57d0501b1959db8629123326c 795 Pfam PF12696 TraM recognition site of TraD and TraG 660 723 2.0E-5 T 29-03-2018 IPR032689 TraD/TraG, TraM recognition site SMALA_RS07520 309677c57d0501b1959db8629123326c 795 SUPERFAMILY SSF52540 373 752 9.86E-33 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS06270 cd611a14e462f68d6673f499cba5f267 265 SUPERFAMILY SSF46955 4 104 3.41E-21 T 29-03-2018 IPR009061 Putative DNA-binding domain SMALA_RS06270 cd611a14e462f68d6673f499cba5f267 265 SMART SM00422 3 72 6.7E-18 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS06270 cd611a14e462f68d6673f499cba5f267 265 Gene3D G3DSA:1.10.1660.10 1 56 1.9E-18 T 29-03-2018 SMALA_RS06270 cd611a14e462f68d6673f499cba5f267 265 Gene3D G3DSA:1.10.1660.10 57 130 2.6E-6 T 29-03-2018 SMALA_RS06270 cd611a14e462f68d6673f499cba5f267 265 Pfam PF00376 MerR family regulatory protein 4 41 3.3E-12 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS16950 95a3c4ef23c58b9d7124e35dc66eeb26 256 Gene3D G3DSA:2.40.440.10 132 251 8.9E-20 T 29-03-2018 SMALA_RS16950 95a3c4ef23c58b9d7124e35dc66eeb26 256 Pfam PF03734 L,D-transpeptidase catalytic domain 140 249 7.2E-13 T 29-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 SMALA_RS16950 95a3c4ef23c58b9d7124e35dc66eeb26 256 SUPERFAMILY SSF141523 139 250 4.71E-21 T 29-03-2018 SMALA_RS19375 5ff6cce60e9b5b2069726ae94bfe9046 359 Pfam PF00005 ABC transporter 28 171 1.4E-26 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS19375 5ff6cce60e9b5b2069726ae94bfe9046 359 SMART SM00382 36 219 3.9E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS19375 5ff6cce60e9b5b2069726ae94bfe9046 359 Gene3D G3DSA:3.40.50.300 10 274 1.4E-57 T 29-03-2018 SMALA_RS19375 5ff6cce60e9b5b2069726ae94bfe9046 359 SUPERFAMILY SSF52540 18 221 5.52E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS32355 4079886514b4a8dff326a04722bd90a5 445 Gene3D G3DSA:1.25.40.10 156 438 5.7E-14 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS32355 4079886514b4a8dff326a04722bd90a5 445 SUPERFAMILY SSF48452 214 363 4.49E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS32005 17a512d056bd868b2e73cc6e62cf2ac9 792 Gene3D G3DSA:1.10.10.650 2 101 6.5E-33 T 29-03-2018 IPR023319 Tex-like protein, HTH domain SMALA_RS32005 17a512d056bd868b2e73cc6e62cf2ac9 792 Gene3D G3DSA:1.10.3500.10 102 355 4.4E-81 T 29-03-2018 IPR023323 Tex-like domain SMALA_RS32005 17a512d056bd868b2e73cc6e62cf2ac9 792 SUPERFAMILY SSF53098 321 469 2.12E-51 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SMALA_RS32005 17a512d056bd868b2e73cc6e62cf2ac9 792 Gene3D G3DSA:2.40.50.140 631 726 4.8E-24 T 29-03-2018 SMALA_RS32005 17a512d056bd868b2e73cc6e62cf2ac9 792 Gene3D G3DSA:1.10.150.310 499 630 9.7E-43 T 29-03-2018 SMALA_RS32005 17a512d056bd868b2e73cc6e62cf2ac9 792 SMART SM00316 649 720 1.1E-24 T 29-03-2018 IPR022967 RNA-binding domain, S1 SMALA_RS32005 17a512d056bd868b2e73cc6e62cf2ac9 792 SUPERFAMILY SSF158832 3 320 2.88E-114 T 29-03-2018 SMALA_RS32005 17a512d056bd868b2e73cc6e62cf2ac9 792 Pfam PF09371 Tex-like protein N-terminal domain 9 193 2.2E-66 T 29-03-2018 IPR018974 Tex-like protein, N-terminal SMALA_RS32005 17a512d056bd868b2e73cc6e62cf2ac9 792 Gene3D G3DSA:1.10.3500.10 356 498 8.0E-39 T 29-03-2018 IPR023323 Tex-like domain SMALA_RS32005 17a512d056bd868b2e73cc6e62cf2ac9 792 Pfam PF16921 Tex protein YqgF-like domain 326 451 1.4E-51 T 29-03-2018 IPR032639 Tex protein, YqgF-like domain SMALA_RS32005 17a512d056bd868b2e73cc6e62cf2ac9 792 SUPERFAMILY SSF50249 638 723 1.34E-23 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMALA_RS32005 17a512d056bd868b2e73cc6e62cf2ac9 792 SUPERFAMILY SSF47781 470 558 1.89E-26 T 29-03-2018 IPR010994 RuvA domain 2-like SMALA_RS32005 17a512d056bd868b2e73cc6e62cf2ac9 792 Pfam PF00575 S1 RNA binding domain 650 720 1.7E-18 T 29-03-2018 IPR003029 S1 domain GO:0003676 SMALA_RS32005 17a512d056bd868b2e73cc6e62cf2ac9 792 SUPERFAMILY SSF47781 560 631 4.89E-19 T 29-03-2018 IPR010994 RuvA domain 2-like SMALA_RS32005 17a512d056bd868b2e73cc6e62cf2ac9 792 SMART SM00732 325 424 5.8E-40 T 29-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 SMALA_RS32005 17a512d056bd868b2e73cc6e62cf2ac9 792 Pfam PF12836 Helix-hairpin-helix motif 491 555 4.0E-27 T 29-03-2018 SMALA_RS06805 605574b67f3d361aa78d2f8fb2283c63 588 Gene3D G3DSA:3.40.50.980 11 181 8.9E-35 T 29-03-2018 SMALA_RS06805 605574b67f3d361aa78d2f8fb2283c63 588 ProSitePatterns PS00455 Putative AMP-binding domain signature. 176 187 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS06805 605574b67f3d361aa78d2f8fb2283c63 588 Gene3D G3DSA:3.40.50.980 182 354 1.3E-36 T 29-03-2018 SMALA_RS06805 605574b67f3d361aa78d2f8fb2283c63 588 Gene3D G3DSA:3.30.300.30 465 573 2.6E-16 T 29-03-2018 SMALA_RS06805 605574b67f3d361aa78d2f8fb2283c63 588 Gene3D G3DSA:2.30.38.10 380 464 2.5E-22 T 29-03-2018 SMALA_RS06805 605574b67f3d361aa78d2f8fb2283c63 588 SUPERFAMILY SSF56801 11 576 2.22E-111 T 29-03-2018 SMALA_RS06805 605574b67f3d361aa78d2f8fb2283c63 588 Pfam PF00501 AMP-binding enzyme 20 471 1.5E-83 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS23305 e43fa238ef59d2b558e16dc1fee3ba74 567 Gene3D G3DSA:2.40.10.10 110 216 4.4E-4 T 29-03-2018 SMALA_RS23305 e43fa238ef59d2b558e16dc1fee3ba74 567 Pfam PF13365 Trypsin-like peptidase domain 27 178 7.5E-10 T 29-03-2018 SMALA_RS23305 e43fa238ef59d2b558e16dc1fee3ba74 567 Gene3D G3DSA:2.40.10.10 3 102 2.4E-7 T 29-03-2018 SMALA_RS23305 e43fa238ef59d2b558e16dc1fee3ba74 567 SUPERFAMILY SSF50494 15 213 3.42E-15 T 29-03-2018 IPR009003 Peptidase S1, PA clan SMALA_RS23370 b561f1468f86ed52a3c3c7e4db533a09 337 Hamap MF_02129 L-carnitine dehydrogenase [lcdH]. 12 324 50.279 T 29-03-2018 IPR026578 L-carnitine dehydrogenase KEGG: 00040+1.1.1.10|MetaCyc: PWY-3602|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-7472 SMALA_RS23370 b561f1468f86ed52a3c3c7e4db533a09 337 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 192 260 5.5E-13 T 29-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 SMALA_RS23370 b561f1468f86ed52a3c3c7e4db533a09 337 SUPERFAMILY SSF48179 192 277 1.19E-11 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMALA_RS23370 b561f1468f86ed52a3c3c7e4db533a09 337 Gene3D G3DSA:1.10.1040.10 194 305 2.6E-15 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMALA_RS23370 b561f1468f86ed52a3c3c7e4db533a09 337 Gene3D G3DSA:3.40.50.720 3 193 1.4E-42 T 29-03-2018 SMALA_RS23370 b561f1468f86ed52a3c3c7e4db533a09 337 SUPERFAMILY SSF51735 11 187 6.31E-46 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS23370 b561f1468f86ed52a3c3c7e4db533a09 337 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 14 186 4.6E-41 T 29-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 SMALA_RS23370 b561f1468f86ed52a3c3c7e4db533a09 337 PIRSF PIRSF000105 7 267 7.3E-58 T 29-03-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 SMALA_RS23370 b561f1468f86ed52a3c3c7e4db533a09 337 PIRSF PIRSF000105 291 321 650.0 T 29-03-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 SMALA_RS09880 c16865f4a4f0424264f213744cea9461 863 TIGRFAM TIGR02412 pepN_strep_liv: aminopeptidase N 4 859 0.0 T 29-03-2018 IPR012778 Peptidase M1, aminopeptidase GO:0004177|GO:0006508 KEGG: 00480+3.4.11.2|MetaCyc: PWY-4061|MetaCyc: PWY-6842|MetaCyc: PWY-7112 SMALA_RS09880 c16865f4a4f0424264f213744cea9461 863 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 181 196 7.2E-21 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMALA_RS09880 c16865f4a4f0424264f213744cea9461 863 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 315 327 7.2E-21 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMALA_RS09880 c16865f4a4f0424264f213744cea9461 863 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 296 311 7.2E-21 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMALA_RS09880 c16865f4a4f0424264f213744cea9461 863 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 135 150 7.2E-21 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMALA_RS09880 c16865f4a4f0424264f213744cea9461 863 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 262 272 7.2E-21 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMALA_RS09880 c16865f4a4f0424264f213744cea9461 863 SUPERFAMILY SSF63737 3 198 8.89E-35 T 29-03-2018 SMALA_RS09880 c16865f4a4f0424264f213744cea9461 863 Pfam PF01433 Peptidase family M1 domain 224 447 1.1E-59 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMALA_RS09880 c16865f4a4f0424264f213744cea9461 863 Gene3D G3DSA:1.10.390.10 282 451 7.3E-48 T 29-03-2018 SMALA_RS09880 c16865f4a4f0424264f213744cea9461 863 Pfam PF11838 ERAP1-like C-terminal domain 533 853 1.3E-49 T 29-03-2018 IPR024571 ERAP1-like C-terminal domain SMALA_RS09880 c16865f4a4f0424264f213744cea9461 863 SUPERFAMILY SSF55486 213 455 2.05E-72 T 29-03-2018 SMALA_RS09880 c16865f4a4f0424264f213744cea9461 863 Gene3D G3DSA:2.60.40.1730 4 199 9.8E-30 T 29-03-2018 SMALA_RS16600 c681f198c84d822bd2e046e574e919d0 465 PIRSF PIRSF002746 20 465 3.1E-141 T 29-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 SMALA_RS16600 c681f198c84d822bd2e046e574e919d0 465 Pfam PF02447 GntP family permease 27 464 5.9E-142 T 29-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 SMALA_RS16600 c681f198c84d822bd2e046e574e919d0 465 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 27 465 1.7E-138 T 29-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 SMALA_RS33025 d715698cbec1914c8177ff7d404417df 156 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 10 139 6.8E-32 T 29-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 SMALA_RS33025 d715698cbec1914c8177ff7d404417df 156 Pfam PF03652 Holliday junction resolvase 7 139 1.5E-43 T 29-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 SMALA_RS33025 d715698cbec1914c8177ff7d404417df 156 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 6 142 23.116 T 29-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 SMALA_RS33025 d715698cbec1914c8177ff7d404417df 156 SUPERFAMILY SSF53098 6 139 6.45E-36 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SMALA_RS33025 d715698cbec1914c8177ff7d404417df 156 Gene3D G3DSA:3.30.420.140 4 150 1.6E-44 T 29-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 SMALA_RS33025 d715698cbec1914c8177ff7d404417df 156 SMART SM00732 6 107 7.4E-34 T 29-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 SMALA_RS04445 c6a92c284c4dc088001fffa9e0ce0677 447 Gene3D G3DSA:3.50.50.60 2 81 4.9E-11 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS04445 c6a92c284c4dc088001fffa9e0ce0677 447 SUPERFAMILY SSF51971 261 317 1.29E-49 T 29-03-2018 SMALA_RS04445 c6a92c284c4dc088001fffa9e0ce0677 447 SUPERFAMILY SSF51971 3 212 1.29E-49 T 29-03-2018 SMALA_RS04445 c6a92c284c4dc088001fffa9e0ce0677 447 Gene3D G3DSA:3.50.50.60 89 317 2.3E-67 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS04445 c6a92c284c4dc088001fffa9e0ce0677 447 PIRSF PIRSF000362 1 446 7.1E-146 T 29-03-2018 IPR021163 Ferredoxin-NADP+ reductase, adrenodoxin-type GO:0016491|GO:0055114 Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 SMALA_RS04445 c6a92c284c4dc088001fffa9e0ce0677 447 PRINTS PR00419 Adrenodoxin reductase family signature 73 83 5.4E-13 T 29-03-2018 SMALA_RS04445 c6a92c284c4dc088001fffa9e0ce0677 447 PRINTS PR00419 Adrenodoxin reductase family signature 3 25 5.4E-13 T 29-03-2018 SMALA_RS04445 c6a92c284c4dc088001fffa9e0ce0677 447 PRINTS PR00419 Adrenodoxin reductase family signature 146 160 5.4E-13 T 29-03-2018 SMALA_RS04445 c6a92c284c4dc088001fffa9e0ce0677 447 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 167 1.1E-8 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS04445 c6a92c284c4dc088001fffa9e0ce0677 447 SUPERFAMILY SSF51971 309 435 3.35E-6 T 29-03-2018 SMALA_RS05735 c0b241176f250c01a2269338830c76f1 257 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMALA_RS05735 c0b241176f250c01a2269338830c76f1 257 Gene3D G3DSA:3.40.50.720 3 47 5.4E-7 T 29-03-2018 SMALA_RS05735 c0b241176f250c01a2269338830c76f1 257 Gene3D G3DSA:3.40.50.720 48 254 2.0E-51 T 29-03-2018 SMALA_RS05735 c0b241176f250c01a2269338830c76f1 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 2.0E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS05735 c0b241176f250c01a2269338830c76f1 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 2.0E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS05735 c0b241176f250c01a2269338830c76f1 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 2.0E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS05735 c0b241176f250c01a2269338830c76f1 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 3.1E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS05735 c0b241176f250c01a2269338830c76f1 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 3.1E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS05735 c0b241176f250c01a2269338830c76f1 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 3.1E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS05735 c0b241176f250c01a2269338830c76f1 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 3.1E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS05735 c0b241176f250c01a2269338830c76f1 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 3.1E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS05735 c0b241176f250c01a2269338830c76f1 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 3.1E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS05735 c0b241176f250c01a2269338830c76f1 257 SUPERFAMILY SSF51735 12 253 6.43E-64 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS05735 c0b241176f250c01a2269338830c76f1 257 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 19 253 4.1E-43 T 29-03-2018 SMALA_RS09735 b5c765cc1f0a414658eb655fe0160da0 500 SUPERFAMILY SSF50249 31 133 8.95E-22 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMALA_RS09735 b5c765cc1f0a414658eb655fe0160da0 500 Gene3D G3DSA:2.40.50.140 201 286 9.3E-27 T 29-03-2018 SMALA_RS09735 b5c765cc1f0a414658eb655fe0160da0 500 Gene3D G3DSA:2.40.50.140 118 197 8.9E-12 T 29-03-2018 SMALA_RS09735 b5c765cc1f0a414658eb655fe0160da0 500 SMART SM00316 37 108 1.9E-16 T 29-03-2018 IPR022967 RNA-binding domain, S1 SMALA_RS09735 b5c765cc1f0a414658eb655fe0160da0 500 SMART SM00316 210 280 1.3E-27 T 29-03-2018 IPR022967 RNA-binding domain, S1 SMALA_RS09735 b5c765cc1f0a414658eb655fe0160da0 500 SMART SM00316 124 191 6.5E-11 T 29-03-2018 IPR022967 RNA-binding domain, S1 SMALA_RS09735 b5c765cc1f0a414658eb655fe0160da0 500 SMART SM00316 295 366 1.1E-26 T 29-03-2018 IPR022967 RNA-binding domain, S1 SMALA_RS09735 b5c765cc1f0a414658eb655fe0160da0 500 Pfam PF00575 S1 RNA binding domain 36 108 5.1E-15 T 29-03-2018 IPR003029 S1 domain GO:0003676 SMALA_RS09735 b5c765cc1f0a414658eb655fe0160da0 500 Pfam PF00575 S1 RNA binding domain 209 280 9.8E-26 T 29-03-2018 IPR003029 S1 domain GO:0003676 SMALA_RS09735 b5c765cc1f0a414658eb655fe0160da0 500 Pfam PF00575 S1 RNA binding domain 124 191 1.1E-13 T 29-03-2018 IPR003029 S1 domain GO:0003676 SMALA_RS09735 b5c765cc1f0a414658eb655fe0160da0 500 Pfam PF00575 S1 RNA binding domain 294 366 3.6E-23 T 29-03-2018 IPR003029 S1 domain GO:0003676 SMALA_RS09735 b5c765cc1f0a414658eb655fe0160da0 500 Gene3D G3DSA:2.40.50.140 16 113 1.4E-17 T 29-03-2018 SMALA_RS09735 b5c765cc1f0a414658eb655fe0160da0 500 SUPERFAMILY SSF50249 113 191 1.34E-14 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMALA_RS09735 b5c765cc1f0a414658eb655fe0160da0 500 SUPERFAMILY SSF50249 207 304 2.93E-27 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMALA_RS09735 b5c765cc1f0a414658eb655fe0160da0 500 PRINTS PR00681 Ribosomal protein S1 signature 175 195 4.1E-86 T 29-03-2018 SMALA_RS09735 b5c765cc1f0a414658eb655fe0160da0 500 PRINTS PR00681 Ribosomal protein S1 signature 39 57 4.1E-86 T 29-03-2018 SMALA_RS09735 b5c765cc1f0a414658eb655fe0160da0 500 PRINTS PR00681 Ribosomal protein S1 signature 232 253 4.1E-86 T 29-03-2018 SMALA_RS09735 b5c765cc1f0a414658eb655fe0160da0 500 PRINTS PR00681 Ribosomal protein S1 signature 57 71 4.1E-86 T 29-03-2018 SMALA_RS09735 b5c765cc1f0a414658eb655fe0160da0 500 PRINTS PR00681 Ribosomal protein S1 signature 146 163 4.1E-86 T 29-03-2018 SMALA_RS09735 b5c765cc1f0a414658eb655fe0160da0 500 PRINTS PR00681 Ribosomal protein S1 signature 310 329 4.1E-86 T 29-03-2018 SMALA_RS09735 b5c765cc1f0a414658eb655fe0160da0 500 PRINTS PR00681 Ribosomal protein S1 signature 105 124 4.1E-86 T 29-03-2018 SMALA_RS09735 b5c765cc1f0a414658eb655fe0160da0 500 PRINTS PR00681 Ribosomal protein S1 signature 129 145 4.1E-86 T 29-03-2018 SMALA_RS09735 b5c765cc1f0a414658eb655fe0160da0 500 PRINTS PR00681 Ribosomal protein S1 signature 349 367 4.1E-86 T 29-03-2018 SMALA_RS09735 b5c765cc1f0a414658eb655fe0160da0 500 Gene3D G3DSA:2.40.50.140 297 448 1.8E-25 T 29-03-2018 SMALA_RS09735 b5c765cc1f0a414658eb655fe0160da0 500 SUPERFAMILY SSF50249 280 368 4.08E-26 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMALA_RS31330 148e7a131c614e08a2e6e5f5fb030df9 225 Gene3D G3DSA:1.10.10.10 9 84 6.6E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS31330 148e7a131c614e08a2e6e5f5fb030df9 225 SUPERFAMILY SSF48008 88 220 1.52E-26 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS31330 148e7a131c614e08a2e6e5f5fb030df9 225 Pfam PF00392 Bacterial regulatory proteins, gntR family 21 82 7.7E-20 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS31330 148e7a131c614e08a2e6e5f5fb030df9 225 SMART SM00345 24 82 4.7E-18 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS31330 148e7a131c614e08a2e6e5f5fb030df9 225 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 56 1.2E-5 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS31330 148e7a131c614e08a2e6e5f5fb030df9 225 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 56 72 1.2E-5 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS31330 148e7a131c614e08a2e6e5f5fb030df9 225 Pfam PF07729 FCD domain 92 213 1.1E-24 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS31330 148e7a131c614e08a2e6e5f5fb030df9 225 SMART SM00895 92 214 1.1E-19 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS31330 148e7a131c614e08a2e6e5f5fb030df9 225 Gene3D G3DSA:1.20.120.530 85 225 1.4E-34 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS31330 148e7a131c614e08a2e6e5f5fb030df9 225 SUPERFAMILY SSF46785 14 107 7.27E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS30755 2336f9f51e2ba4c6c78a93b458e37057 280 Pfam PF00795 Carbon-nitrogen hydrolase 6 261 2.7E-67 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMALA_RS30755 2336f9f51e2ba4c6c78a93b458e37057 280 SUPERFAMILY SSF56317 4 277 2.09E-80 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMALA_RS30755 2336f9f51e2ba4c6c78a93b458e37057 280 Gene3D G3DSA:3.60.110.10 4 276 4.0E-76 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMALA_RS24560 b1ce0e9340dc073eb10309818aecf7e9 77 Pfam PF04149 Domain of unknown function (DUF397) 16 70 3.8E-22 T 29-03-2018 IPR007278 Domain of unknown function DUF397 SMALA_RS08400 60374e60baf5a58918ee79bd52e00210 395 SUPERFAMILY SSF48264 3 395 1.7E-100 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS08400 60374e60baf5a58918ee79bd52e00210 395 Pfam PF00067 Cytochrome P450 154 365 1.2E-26 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS08400 60374e60baf5a58918ee79bd52e00210 395 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 337 346 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMALA_RS08400 60374e60baf5a58918ee79bd52e00210 395 PRINTS PR00359 B-class P450 signature 134 150 5.2E-50 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS08400 60374e60baf5a58918ee79bd52e00210 395 PRINTS PR00359 B-class P450 signature 89 100 5.2E-50 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS08400 60374e60baf5a58918ee79bd52e00210 395 PRINTS PR00359 B-class P450 signature 288 315 5.2E-50 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS08400 60374e60baf5a58918ee79bd52e00210 395 PRINTS PR00359 B-class P450 signature 151 166 5.2E-50 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS08400 60374e60baf5a58918ee79bd52e00210 395 PRINTS PR00359 B-class P450 signature 344 355 5.2E-50 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS08400 60374e60baf5a58918ee79bd52e00210 395 PRINTS PR00359 B-class P450 signature 189 211 5.2E-50 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS08400 60374e60baf5a58918ee79bd52e00210 395 PRINTS PR00359 B-class P450 signature 270 281 5.2E-50 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS08400 60374e60baf5a58918ee79bd52e00210 395 PRINTS PR00359 B-class P450 signature 335 344 5.2E-50 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS08400 60374e60baf5a58918ee79bd52e00210 395 Gene3D G3DSA:1.10.630.10 5 395 2.5E-88 T 29-03-2018 SMALA_RS14390 65eb458b3cd176a81c93e08e8f714579 391 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 101 358 1.2E-28 T 29-03-2018 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 SMALA_RS14390 65eb458b3cd176a81c93e08e8f714579 391 Gene3D G3DSA:3.20.20.80 38 386 4.2E-38 T 29-03-2018 SMALA_RS14390 65eb458b3cd176a81c93e08e8f714579 391 SUPERFAMILY SSF51445 57 389 4.65E-49 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS43090 4590e19b1fb8057807a400175e07cbe8 393 SUPERFAMILY SSF53098 318 378 1.57E-25 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SMALA_RS43090 4590e19b1fb8057807a400175e07cbe8 393 SUPERFAMILY SSF53098 181 287 1.57E-25 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SMALA_RS43090 4590e19b1fb8057807a400175e07cbe8 393 Pfam PF00929 Exonuclease 185 280 5.1E-13 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III SMALA_RS43090 4590e19b1fb8057807a400175e07cbe8 393 Gene3D G3DSA:3.30.420.10 180 382 2.2E-22 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SMALA_RS43090 4590e19b1fb8057807a400175e07cbe8 393 SMART SM00479 183 376 1.6E-16 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III SMALA_RS42395 0263684473f9005a0f5e5d500eb609e1 303 Gene3D G3DSA:3.40.50.720 1 294 7.2E-23 T 29-03-2018 SMALA_RS42395 0263684473f9005a0f5e5d500eb609e1 303 SUPERFAMILY SSF51735 1 293 4.42E-33 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS42395 0263684473f9005a0f5e5d500eb609e1 303 Pfam PF13460 NAD(P)H-binding 7 96 2.7E-7 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS06815 960ad61478b268d9ade92e4f4e926692 147 Pfam PF01220 Dehydroquinase class II 4 139 1.7E-46 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SMALA_RS06815 960ad61478b268d9ade92e4f4e926692 147 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 147 52.671 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SMALA_RS06815 960ad61478b268d9ade92e4f4e926692 147 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 17 125 5.0E-56 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SMALA_RS06815 960ad61478b268d9ade92e4f4e926692 147 SUPERFAMILY SSF52304 3 143 1.27E-50 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SMALA_RS06815 960ad61478b268d9ade92e4f4e926692 147 PIRSF PIRSF001399 1 145 6.8E-49 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SMALA_RS06815 960ad61478b268d9ade92e4f4e926692 147 Gene3D G3DSA:3.40.50.9100 1 145 4.3E-49 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SMALA_RS06815 960ad61478b268d9ade92e4f4e926692 147 ProSitePatterns PS01029 Dehydroquinase class II signature. 7 24 - T 29-03-2018 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SMALA_RS38765 4a59049c122e28e281e3c542501da440 381 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 71 84 - T 29-03-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 SMALA_RS38765 4a59049c122e28e281e3c542501da440 381 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 23 127 2.2E-18 T 29-03-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 SMALA_RS38765 4a59049c122e28e281e3c542501da440 381 SMART SM00839 143 377 3.8E-77 T 29-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 SMALA_RS38765 4a59049c122e28e281e3c542501da440 381 SUPERFAMILY SSF51735 143 377 8.52E-55 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS38765 4a59049c122e28e281e3c542501da440 381 SUPERFAMILY SSF53223 10 144 1.38E-32 T 29-03-2018 SMALA_RS38765 4a59049c122e28e281e3c542501da440 381 Gene3D G3DSA:3.40.50.720 151 380 1.1E-54 T 29-03-2018 SMALA_RS38765 4a59049c122e28e281e3c542501da440 381 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 173 189 - T 29-03-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 SMALA_RS38765 4a59049c122e28e281e3c542501da440 381 PIRSF PIRSF000185 11 379 4.3E-99 T 29-03-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 SMALA_RS38765 4a59049c122e28e281e3c542501da440 381 Gene3D G3DSA:3.40.50.10860 15 150 6.2E-34 T 29-03-2018 SMALA_RS38765 4a59049c122e28e281e3c542501da440 381 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 176 196 3.0E-11 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 SMALA_RS38765 4a59049c122e28e281e3c542501da440 381 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 305 316 3.0E-11 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 SMALA_RS38765 4a59049c122e28e281e3c542501da440 381 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 63 77 3.0E-11 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 SMALA_RS38765 4a59049c122e28e281e3c542501da440 381 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 142 377 2.1E-51 T 29-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 SMALA_RS31540 4e0a36855c67f90ec4b732ecfcf40cd6 232 Pfam PF01965 DJ-1/PfpI family 30 218 1.6E-14 T 29-03-2018 IPR002818 DJ-1/PfpI SMALA_RS31540 4e0a36855c67f90ec4b732ecfcf40cd6 232 Gene3D G3DSA:3.40.50.880 1 231 5.7E-53 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS31540 4e0a36855c67f90ec4b732ecfcf40cd6 232 SUPERFAMILY SSF52317 2 229 3.28E-59 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS37320 5fc3c2c152d0f2f87576a24c30f345d2 246 Pfam PF01144 Coenzyme A transferase 86 204 2.4E-7 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 SMALA_RS37320 5fc3c2c152d0f2f87576a24c30f345d2 246 SMART SM00882 9 205 0.0058 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 SMALA_RS37320 5fc3c2c152d0f2f87576a24c30f345d2 246 Gene3D G3DSA:3.40.1080.10 2 244 2.2E-36 T 29-03-2018 SMALA_RS37320 5fc3c2c152d0f2f87576a24c30f345d2 246 SUPERFAMILY SSF100950 5 243 3.27E-52 T 29-03-2018 SMALA_RS13705 277c8b44b5f746ce8b695197e46acb49 379 SUPERFAMILY SSF158745 12 378 1.15E-66 T 29-03-2018 SMALA_RS13705 277c8b44b5f746ce8b695197e46acb49 379 PRINTS PR01955 Frankia sp. LanC-like protein signature 14 29 3.7E-74 T 29-03-2018 SMALA_RS13705 277c8b44b5f746ce8b695197e46acb49 379 PRINTS PR01955 Frankia sp. LanC-like protein signature 116 132 3.7E-74 T 29-03-2018 SMALA_RS13705 277c8b44b5f746ce8b695197e46acb49 379 PRINTS PR01955 Frankia sp. LanC-like protein signature 347 364 3.7E-74 T 29-03-2018 SMALA_RS13705 277c8b44b5f746ce8b695197e46acb49 379 PRINTS PR01955 Frankia sp. LanC-like protein signature 251 274 3.7E-74 T 29-03-2018 SMALA_RS13705 277c8b44b5f746ce8b695197e46acb49 379 PRINTS PR01955 Frankia sp. LanC-like protein signature 300 320 3.7E-74 T 29-03-2018 SMALA_RS13705 277c8b44b5f746ce8b695197e46acb49 379 PRINTS PR01955 Frankia sp. LanC-like protein signature 181 205 3.7E-74 T 29-03-2018 SMALA_RS13705 277c8b44b5f746ce8b695197e46acb49 379 PRINTS PR01955 Frankia sp. LanC-like protein signature 57 73 3.7E-74 T 29-03-2018 SMALA_RS13705 277c8b44b5f746ce8b695197e46acb49 379 PRINTS PR01955 Frankia sp. LanC-like protein signature 138 154 3.7E-74 T 29-03-2018 SMALA_RS13705 277c8b44b5f746ce8b695197e46acb49 379 Pfam PF05147 Lanthionine synthetase C-like protein 12 376 1.4E-37 T 29-03-2018 IPR007822 Lanthionine synthetase C-like SMALA_RS13705 277c8b44b5f746ce8b695197e46acb49 379 SMART SM01260 10 377 1.4E-52 T 29-03-2018 IPR007822 Lanthionine synthetase C-like SMALA_RS13705 277c8b44b5f746ce8b695197e46acb49 379 PRINTS PR01950 LanC-like protein superfamily signature 251 271 9.2E-19 T 29-03-2018 IPR007822 Lanthionine synthetase C-like SMALA_RS13705 277c8b44b5f746ce8b695197e46acb49 379 PRINTS PR01950 LanC-like protein superfamily signature 117 132 9.2E-19 T 29-03-2018 IPR007822 Lanthionine synthetase C-like SMALA_RS13705 277c8b44b5f746ce8b695197e46acb49 379 PRINTS PR01950 LanC-like protein superfamily signature 13 31 9.2E-19 T 29-03-2018 IPR007822 Lanthionine synthetase C-like SMALA_RS13705 277c8b44b5f746ce8b695197e46acb49 379 PRINTS PR01950 LanC-like protein superfamily signature 184 200 9.2E-19 T 29-03-2018 IPR007822 Lanthionine synthetase C-like SMALA_RS13705 277c8b44b5f746ce8b695197e46acb49 379 PRINTS PR01950 LanC-like protein superfamily signature 301 314 9.2E-19 T 29-03-2018 IPR007822 Lanthionine synthetase C-like SMALA_RS13705 277c8b44b5f746ce8b695197e46acb49 379 PRINTS PR01950 LanC-like protein superfamily signature 346 363 9.2E-19 T 29-03-2018 IPR007822 Lanthionine synthetase C-like SMALA_RS31335 38feea05389179e4ee29b892658d7553 95 SUPERFAMILY SSF54736 62 92 1.34E-5 T 29-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like SMALA_RS31335 38feea05389179e4ee29b892658d7553 95 Gene3D G3DSA:3.30.1390.10 30 94 2.2E-13 T 29-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like SMALA_RS31335 38feea05389179e4ee29b892658d7553 95 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 63 91 2.8E-7 T 29-03-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS18280 1664f5b38bf0d7fc19d31e0036a2a72f 431 Pfam PF13641 Glycosyltransferase like family 2 53 283 2.2E-39 T 29-03-2018 SMALA_RS18280 1664f5b38bf0d7fc19d31e0036a2a72f 431 Gene3D G3DSA:3.90.550.10 22 315 1.7E-40 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS18280 1664f5b38bf0d7fc19d31e0036a2a72f 431 SUPERFAMILY SSF53448 44 330 3.21E-38 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS30190 0250191a9144544b9da75c8a70abe5e5 304 Pfam PF00398 Ribosomal RNA adenine dimethylase 24 277 2.7E-47 T 29-03-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm SMALA_RS30190 0250191a9144544b9da75c8a70abe5e5 304 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 56 83 - T 29-03-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 SMALA_RS30190 0250191a9144544b9da75c8a70abe5e5 304 SUPERFAMILY SSF53335 23 279 1.27E-43 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS30190 0250191a9144544b9da75c8a70abe5e5 304 SMART SM00650 40 205 2.5E-66 T 29-03-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 SMALA_RS30190 0250191a9144544b9da75c8a70abe5e5 304 Gene3D G3DSA:3.40.50.150 1 223 6.4E-35 T 29-03-2018 SMALA_RS41990 5c8d658014283f93a9cc455a9ac62951 393 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 334 343 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMALA_RS41990 5c8d658014283f93a9cc455a9ac62951 393 Gene3D G3DSA:1.10.630.10 4 389 1.1E-63 T 29-03-2018 SMALA_RS41990 5c8d658014283f93a9cc455a9ac62951 393 Pfam PF00067 Cytochrome P450 200 362 9.3E-25 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS41990 5c8d658014283f93a9cc455a9ac62951 393 PRINTS PR00359 B-class P450 signature 283 310 3.7E-42 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS41990 5c8d658014283f93a9cc455a9ac62951 393 PRINTS PR00359 B-class P450 signature 332 341 3.7E-42 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS41990 5c8d658014283f93a9cc455a9ac62951 393 PRINTS PR00359 B-class P450 signature 80 91 3.7E-42 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS41990 5c8d658014283f93a9cc455a9ac62951 393 PRINTS PR00359 B-class P450 signature 184 206 3.7E-42 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS41990 5c8d658014283f93a9cc455a9ac62951 393 PRINTS PR00359 B-class P450 signature 341 352 3.7E-42 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS41990 5c8d658014283f93a9cc455a9ac62951 393 PRINTS PR00359 B-class P450 signature 311 326 3.7E-42 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS41990 5c8d658014283f93a9cc455a9ac62951 393 PRINTS PR00359 B-class P450 signature 127 143 3.7E-42 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS41990 5c8d658014283f93a9cc455a9ac62951 393 PRINTS PR00359 B-class P450 signature 265 276 3.7E-42 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS41990 5c8d658014283f93a9cc455a9ac62951 393 SUPERFAMILY SSF48264 30 389 4.32E-82 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS28020 0e33b565f4e20ea6e5cd5415d1fc8986 278 SUPERFAMILY SSF69065 18 179 8.89E-49 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 SMALA_RS28020 0e33b565f4e20ea6e5cd5415d1fc8986 278 Gene3D G3DSA:1.10.1520.10 9 165 2.8E-43 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 SMALA_RS28020 0e33b565f4e20ea6e5cd5415d1fc8986 278 Pfam PF14622 Ribonuclease-III-like 36 161 1.7E-37 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 SMALA_RS28020 0e33b565f4e20ea6e5cd5415d1fc8986 278 SMART SM00535 37 170 6.9E-60 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 SMALA_RS28020 0e33b565f4e20ea6e5cd5415d1fc8986 278 SUPERFAMILY SSF54768 131 243 2.04E-26 T 29-03-2018 SMALA_RS28020 0e33b565f4e20ea6e5cd5415d1fc8986 278 ProSitePatterns PS00517 Ribonuclease III family signature. 59 67 - T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 SMALA_RS28020 0e33b565f4e20ea6e5cd5415d1fc8986 278 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 28 241 1.7E-72 T 29-03-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 SMALA_RS28020 0e33b565f4e20ea6e5cd5415d1fc8986 278 Gene3D G3DSA:3.30.160.20 166 239 9.3E-22 T 29-03-2018 SMALA_RS28020 0e33b565f4e20ea6e5cd5415d1fc8986 278 Hamap MF_00104 Ribonuclease 3 [rnc]. 26 239 30.364 T 29-03-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 SMALA_RS28020 0e33b565f4e20ea6e5cd5415d1fc8986 278 Pfam PF00035 Double-stranded RNA binding motif 177 240 7.3E-18 T 29-03-2018 IPR014720 Double-stranded RNA-binding domain SMALA_RS28020 0e33b565f4e20ea6e5cd5415d1fc8986 278 SMART SM00358 177 243 3.0E-24 T 29-03-2018 IPR014720 Double-stranded RNA-binding domain SMALA_RS40755 79e80e91005d92105a78dae5363ff96d 327 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 151 323 1.1E-24 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS40755 79e80e91005d92105a78dae5363ff96d 327 Gene3D G3DSA:1.10.3720.10 83 327 3.7E-29 T 29-03-2018 SMALA_RS40755 79e80e91005d92105a78dae5363ff96d 327 SUPERFAMILY SSF161098 130 317 5.36E-32 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS25940 02d978414d3ea2096611c1b00663000a 344 Gene3D G3DSA:3.40.50.1820 28 326 1.6E-47 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS25940 02d978414d3ea2096611c1b00663000a 344 SUPERFAMILY SSF53474 28 316 2.16E-53 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS25940 02d978414d3ea2096611c1b00663000a 344 Pfam PF00561 alpha/beta hydrolase fold 55 300 2.5E-25 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS25940 02d978414d3ea2096611c1b00663000a 344 PRINTS PR00111 Alpha/beta hydrolase fold signature 136 149 7.4E-6 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS25940 02d978414d3ea2096611c1b00663000a 344 PRINTS PR00111 Alpha/beta hydrolase fold signature 77 92 7.4E-6 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS25940 02d978414d3ea2096611c1b00663000a 344 PRINTS PR00111 Alpha/beta hydrolase fold signature 122 135 7.4E-6 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS42340 e1caefb6e31e31c0380736224479d168 236 ProSitePatterns PS00221 MIP family signature. 51 59 - T 29-03-2018 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMALA_RS42340 e1caefb6e31e31c0380736224479d168 236 PRINTS PR00783 Major intrinsic protein family signature 33 57 6.0E-39 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMALA_RS42340 e1caefb6e31e31c0380736224479d168 236 PRINTS PR00783 Major intrinsic protein family signature 184 204 6.0E-39 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMALA_RS42340 e1caefb6e31e31c0380736224479d168 236 PRINTS PR00783 Major intrinsic protein family signature 2 21 6.0E-39 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMALA_RS42340 e1caefb6e31e31c0380736224479d168 236 PRINTS PR00783 Major intrinsic protein family signature 70 89 6.0E-39 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMALA_RS42340 e1caefb6e31e31c0380736224479d168 236 PRINTS PR00783 Major intrinsic protein family signature 146 168 6.0E-39 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMALA_RS42340 e1caefb6e31e31c0380736224479d168 236 PRINTS PR00783 Major intrinsic protein family signature 114 132 6.0E-39 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMALA_RS42340 e1caefb6e31e31c0380736224479d168 236 Pfam PF00230 Major intrinsic protein 1 200 3.9E-33 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMALA_RS42340 e1caefb6e31e31c0380736224479d168 236 Gene3D G3DSA:1.20.1080.10 1 219 1.8E-44 T 29-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 SMALA_RS42340 e1caefb6e31e31c0380736224479d168 236 SUPERFAMILY SSF81338 2 207 2.88E-45 T 29-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 SMALA_RS29645 e572564423567ef529d7cec6d9f135b2 342 SUPERFAMILY SSF53613 28 331 2.81E-65 T 29-03-2018 IPR029056 Ribokinase-like SMALA_RS29645 e572564423567ef529d7cec6d9f135b2 342 Gene3D G3DSA:3.40.1190.20 28 336 8.7E-59 T 29-03-2018 IPR029056 Ribokinase-like SMALA_RS29645 e572564423567ef529d7cec6d9f135b2 342 Pfam PF00294 pfkB family carbohydrate kinase 29 323 1.0E-48 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB SMALA_RS12870 3124dc6137fbb4b51b78deb801892cb2 236 Gene3D G3DSA:1.10.3680.10 82 236 3.2E-19 T 29-03-2018 IPR029024 TerB-like SMALA_RS12870 3124dc6137fbb4b51b78deb801892cb2 236 Pfam PF05099 Tellurite resistance protein TerB 92 228 1.7E-9 T 29-03-2018 IPR007791 Co-chaperone DjlA, N-terminal SMALA_RS12870 3124dc6137fbb4b51b78deb801892cb2 236 SUPERFAMILY SSF158682 88 230 1.96E-9 T 29-03-2018 SMALA_RS12810 5cbef0841c1bcc03a30fa891a83d4dbb 342 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 284 327 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 SMALA_RS12810 5cbef0841c1bcc03a30fa891a83d4dbb 342 SUPERFAMILY SSF46689 283 334 3.08E-10 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS12810 5cbef0841c1bcc03a30fa891a83d4dbb 342 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 315 331 2.0E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SMALA_RS12810 5cbef0841c1bcc03a30fa891a83d4dbb 342 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 300 315 2.0E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SMALA_RS12810 5cbef0841c1bcc03a30fa891a83d4dbb 342 Gene3D G3DSA:1.10.10.60 287 337 1.6E-11 T 29-03-2018 SMALA_RS12810 5cbef0841c1bcc03a30fa891a83d4dbb 342 Pfam PF12833 Helix-turn-helix domain 253 332 3.1E-21 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS12810 5cbef0841c1bcc03a30fa891a83d4dbb 342 SMART SM00342 247 331 3.9E-31 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS12810 5cbef0841c1bcc03a30fa891a83d4dbb 342 SUPERFAMILY SSF46689 230 281 9.86E-7 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS12810 5cbef0841c1bcc03a30fa891a83d4dbb 342 Pfam PF12852 Cupin 2 215 3.0E-46 T 29-03-2018 IPR032783 AraC-type transcription regulator, ligand-binding domain SMALA_RS12810 5cbef0841c1bcc03a30fa891a83d4dbb 342 Gene3D G3DSA:1.10.10.60 3 286 4.9E-12 T 29-03-2018 SMALA_RS14700 70ce0926bb0d978ed55fca0fd9a5d285 131 Gene3D G3DSA:3.40.1260.10 6 130 2.6E-4 T 29-03-2018 SMALA_RS06715 3ab76d4bca53ba7754c91442d83146aa 140 Gene3D G3DSA:3.40.50.280 1 140 9.3E-31 T 29-03-2018 SMALA_RS06715 3ab76d4bca53ba7754c91442d83146aa 140 SUPERFAMILY SSF52242 8 134 7.33E-39 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 SMALA_RS06715 3ab76d4bca53ba7754c91442d83146aa 140 Pfam PF02310 B12 binding domain 14 127 2.9E-22 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 SMALA_RS06715 3ab76d4bca53ba7754c91442d83146aa 140 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 13 135 3.3E-38 T 29-03-2018 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMALA_RS10820 3fcf1b4afea8741e420623315bde064c 731 Pfam PF03176 MMPL family 467 704 9.5E-38 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 SMALA_RS10820 3fcf1b4afea8741e420623315bde064c 731 Pfam PF03176 MMPL family 90 333 2.3E-41 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 SMALA_RS10820 3fcf1b4afea8741e420623315bde064c 731 SUPERFAMILY SSF82866 477 700 1.83E-30 T 29-03-2018 SMALA_RS10820 3fcf1b4afea8741e420623315bde064c 731 Gene3D G3DSA:1.20.1640.10 121 333 4.7E-32 T 29-03-2018 SMALA_RS10820 3fcf1b4afea8741e420623315bde064c 731 Gene3D G3DSA:1.20.1640.10 478 699 2.7E-37 T 29-03-2018 SMALA_RS10820 3fcf1b4afea8741e420623315bde064c 731 SUPERFAMILY SSF82866 107 332 1.24E-33 T 29-03-2018 SMALA_RS38875 e4f7af13c9ea59c4b360bd352ea86d55 239 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 77 221 5.3E-15 T 29-03-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 SMALA_RS38875 e4f7af13c9ea59c4b360bd352ea86d55 239 SUPERFAMILY SSF48498 81 222 1.67E-20 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS38875 e4f7af13c9ea59c4b360bd352ea86d55 239 Gene3D G3DSA:1.10.10.60 9 72 5.2E-15 T 29-03-2018 SMALA_RS38875 e4f7af13c9ea59c4b360bd352ea86d55 239 Gene3D G3DSA:1.10.357.10 73 225 1.6E-21 T 29-03-2018 SMALA_RS38875 e4f7af13c9ea59c4b360bd352ea86d55 239 SUPERFAMILY SSF46689 12 73 2.72E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS38875 e4f7af13c9ea59c4b360bd352ea86d55 239 PRINTS PR00400 Tetracycline repressor protein signature 31 54 8.9E-6 T 29-03-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 SMALA_RS38875 e4f7af13c9ea59c4b360bd352ea86d55 239 PRINTS PR00400 Tetracycline repressor protein signature 205 219 8.9E-6 T 29-03-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 SMALA_RS38875 e4f7af13c9ea59c4b360bd352ea86d55 239 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 63 1.5E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS09700 b063e24b5d54403cd1443e65e66e7f2d 407 Pfam PF06081 Aromatic acid exporter family member 1 22 157 7.9E-9 T 29-03-2018 IPR010343 Aromatic acid exporter family member 1 SMALA_RS17950 f2b3e440d9e70a2f619e87ce191f4e75 841 Gene3D G3DSA:1.10.1780.10 78 196 4.3E-30 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 SMALA_RS17950 f2b3e440d9e70a2f619e87ce191f4e75 841 Gene3D G3DSA:1.10.8.60 348 491 3.3E-41 T 29-03-2018 SMALA_RS17950 f2b3e440d9e70a2f619e87ce191f4e75 841 SUPERFAMILY SSF81923 3 144 3.63E-33 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 SMALA_RS17950 f2b3e440d9e70a2f619e87ce191f4e75 841 SMART SM00382 541 689 5.9E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS17950 f2b3e440d9e70a2f619e87ce191f4e75 841 SMART SM00382 204 348 6.5E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS17950 f2b3e440d9e70a2f619e87ce191f4e75 841 Pfam PF07724 AAA domain (Cdc48 subfamily) 541 712 2.0E-54 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 SMALA_RS17950 f2b3e440d9e70a2f619e87ce191f4e75 841 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 719 798 1.9E-26 T 29-03-2018 IPR019489 Clp ATPase, C-terminal SMALA_RS17950 f2b3e440d9e70a2f619e87ce191f4e75 841 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 16 68 3.2E-19 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 SMALA_RS17950 f2b3e440d9e70a2f619e87ce191f4e75 841 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 93 142 4.6E-17 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 SMALA_RS17950 f2b3e440d9e70a2f619e87ce191f4e75 841 SMART SM01086 719 812 5.3E-37 T 29-03-2018 IPR019489 Clp ATPase, C-terminal SMALA_RS17950 f2b3e440d9e70a2f619e87ce191f4e75 841 Gene3D G3DSA:1.10.8.60 719 822 8.4E-25 T 29-03-2018 SMALA_RS17950 f2b3e440d9e70a2f619e87ce191f4e75 841 Pfam PF02151 UvrB/uvrC motif 421 453 1.8E-5 T 29-03-2018 IPR001943 UVR domain GO:0005515 SMALA_RS17950 f2b3e440d9e70a2f619e87ce191f4e75 841 Gene3D G3DSA:1.10.1780.10 1 77 9.7E-29 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 SMALA_RS17950 f2b3e440d9e70a2f619e87ce191f4e75 841 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 299 311 - T 29-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 SMALA_RS17950 f2b3e440d9e70a2f619e87ce191f4e75 841 SUPERFAMILY SSF52540 490 801 7.06E-79 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS17950 f2b3e440d9e70a2f619e87ce191f4e75 841 Gene3D G3DSA:3.40.50.300 197 346 1.8E-18 T 29-03-2018 SMALA_RS17950 f2b3e440d9e70a2f619e87ce191f4e75 841 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 619 637 6.2E-40 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 SMALA_RS17950 f2b3e440d9e70a2f619e87ce191f4e75 841 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 545 563 6.2E-40 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 SMALA_RS17950 f2b3e440d9e70a2f619e87ce191f4e75 841 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 590 608 6.2E-40 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 SMALA_RS17950 f2b3e440d9e70a2f619e87ce191f4e75 841 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 652 666 6.2E-40 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 SMALA_RS17950 f2b3e440d9e70a2f619e87ce191f4e75 841 Gene3D G3DSA:3.40.50.300 496 718 1.1E-56 T 29-03-2018 SMALA_RS17950 f2b3e440d9e70a2f619e87ce191f4e75 841 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 209 321 2.5E-12 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 SMALA_RS17950 f2b3e440d9e70a2f619e87ce191f4e75 841 SUPERFAMILY SSF52540 167 450 6.0E-74 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS22500 8086c4e7e291a885ce9eb014a90b627d 123 Pfam PF00164 Ribosomal protein S12/S23 12 123 2.9E-42 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS22500 8086c4e7e291a885ce9eb014a90b627d 123 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 123 39.334 T 29-03-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS22500 8086c4e7e291a885ce9eb014a90b627d 123 ProSitePatterns PS00055 Ribosomal protein S12 signature. 43 50 - T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS22500 8086c4e7e291a885ce9eb014a90b627d 123 SUPERFAMILY SSF50249 2 123 1.11E-51 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMALA_RS22500 8086c4e7e291a885ce9eb014a90b627d 123 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 2 123 2.9E-66 T 29-03-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS22500 8086c4e7e291a885ce9eb014a90b627d 123 Gene3D G3DSA:2.40.50.140 1 123 1.3E-63 T 29-03-2018 SMALA_RS22500 8086c4e7e291a885ce9eb014a90b627d 123 PIRSF PIRSF002133 1 123 2.9E-53 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS22500 8086c4e7e291a885ce9eb014a90b627d 123 PRINTS PR01034 Ribosomal protein S12 signature 110 122 6.4E-58 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS22500 8086c4e7e291a885ce9eb014a90b627d 123 PRINTS PR01034 Ribosomal protein S12 signature 94 110 6.4E-58 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS22500 8086c4e7e291a885ce9eb014a90b627d 123 PRINTS PR01034 Ribosomal protein S12 signature 27 42 6.4E-58 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS22500 8086c4e7e291a885ce9eb014a90b627d 123 PRINTS PR01034 Ribosomal protein S12 signature 58 77 6.4E-58 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS22500 8086c4e7e291a885ce9eb014a90b627d 123 PRINTS PR01034 Ribosomal protein S12 signature 42 57 6.4E-58 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS22500 8086c4e7e291a885ce9eb014a90b627d 123 PRINTS PR01034 Ribosomal protein S12 signature 77 94 6.4E-58 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS26335 c50e61185a759f224e13d38c3bfb8c09 322 SUPERFAMILY SSF111331 1 322 1.29E-50 T 29-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain SMALA_RS26335 c50e61185a759f224e13d38c3bfb8c09 322 Gene3D G3DSA:3.40.50.10330 1 127 1.7E-26 T 29-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 SMALA_RS26335 c50e61185a759f224e13d38c3bfb8c09 322 SMART SM00046 2 133 4.8E-8 T 29-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 SMALA_RS26335 c50e61185a759f224e13d38c3bfb8c09 322 Pfam PF00781 Diacylglycerol kinase catalytic domain 2 118 1.5E-25 T 29-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 SMALA_RS01810 dac9448a9bb2ae940cba793fb6ea15aa 254 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 252 7.5E-59 T 29-03-2018 SMALA_RS01810 dac9448a9bb2ae940cba793fb6ea15aa 254 Gene3D G3DSA:3.40.50.720 45 254 8.2E-58 T 29-03-2018 SMALA_RS01810 dac9448a9bb2ae940cba793fb6ea15aa 254 Gene3D G3DSA:3.40.50.720 1 44 2.5E-9 T 29-03-2018 SMALA_RS01810 dac9448a9bb2ae940cba793fb6ea15aa 254 SUPERFAMILY SSF51735 5 253 1.22E-73 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS01810 dac9448a9bb2ae940cba793fb6ea15aa 254 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMALA_RS01810 dac9448a9bb2ae940cba793fb6ea15aa 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 1.2E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS01810 dac9448a9bb2ae940cba793fb6ea15aa 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 1.2E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS01810 dac9448a9bb2ae940cba793fb6ea15aa 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 1.2E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS01810 dac9448a9bb2ae940cba793fb6ea15aa 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 1.3E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS01810 dac9448a9bb2ae940cba793fb6ea15aa 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 1.3E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS01810 dac9448a9bb2ae940cba793fb6ea15aa 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 1.3E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS01810 dac9448a9bb2ae940cba793fb6ea15aa 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 1.3E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS01810 dac9448a9bb2ae940cba793fb6ea15aa 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 1.3E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS01810 dac9448a9bb2ae940cba793fb6ea15aa 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 1.3E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS35695 8db9ee73644ce3ab10634d5ed5475fe4 260 Gene3D G3DSA:3.60.15.10 1 253 1.6E-26 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS35695 8db9ee73644ce3ab10634d5ed5475fe4 260 SUPERFAMILY SSF56281 1 72 1.08E-23 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS35695 8db9ee73644ce3ab10634d5ed5475fe4 260 SUPERFAMILY SSF56281 109 230 1.08E-23 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS35695 8db9ee73644ce3ab10634d5ed5475fe4 260 Pfam PF12706 Beta-lactamase superfamily domain 18 218 1.4E-17 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS36960 781a475ae84cae724de085babeced0b3 188 Gene3D G3DSA:1.10.443.10 19 186 1.4E-10 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 SMALA_RS36960 781a475ae84cae724de085babeced0b3 188 Pfam PF00589 Phage integrase family 40 167 3.3E-7 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 SMALA_RS36960 781a475ae84cae724de085babeced0b3 188 SUPERFAMILY SSF56349 45 167 5.0E-10 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 SMALA_RS22640 901b075f06f1c923d5976d7f0eb627e3 437 ProSitePatterns PS00755 Protein secY signature 1. 73 92 - T 29-03-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 SMALA_RS22640 901b075f06f1c923d5976d7f0eb627e3 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 274 293 6.1E-107 T 29-03-2018 SMALA_RS22640 901b075f06f1c923d5976d7f0eb627e3 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 113 136 6.1E-107 T 29-03-2018 SMALA_RS22640 901b075f06f1c923d5976d7f0eb627e3 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 183 206 6.1E-107 T 29-03-2018 SMALA_RS22640 901b075f06f1c923d5976d7f0eb627e3 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 371 389 6.1E-107 T 29-03-2018 SMALA_RS22640 901b075f06f1c923d5976d7f0eb627e3 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 157 182 6.1E-107 T 29-03-2018 SMALA_RS22640 901b075f06f1c923d5976d7f0eb627e3 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 316 338 6.1E-107 T 29-03-2018 SMALA_RS22640 901b075f06f1c923d5976d7f0eb627e3 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 18 36 6.1E-107 T 29-03-2018 SMALA_RS22640 901b075f06f1c923d5976d7f0eb627e3 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 72 92 6.1E-107 T 29-03-2018 SMALA_RS22640 901b075f06f1c923d5976d7f0eb627e3 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 405 423 6.1E-107 T 29-03-2018 SMALA_RS22640 901b075f06f1c923d5976d7f0eb627e3 437 PIRSF PIRSF004557 1 437 1.1E-124 T 29-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 SMALA_RS22640 901b075f06f1c923d5976d7f0eb627e3 437 ProSitePatterns PS00756 Protein secY signature 2. 176 193 - T 29-03-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 SMALA_RS22640 901b075f06f1c923d5976d7f0eb627e3 437 Gene3D G3DSA:1.10.3370.10 1 437 9.3E-164 T 29-03-2018 SMALA_RS22640 901b075f06f1c923d5976d7f0eb627e3 437 SUPERFAMILY SSF103491 2 427 1.2E-127 T 29-03-2018 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 SMALA_RS22640 901b075f06f1c923d5976d7f0eb627e3 437 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 15 432 3.4E-148 T 29-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 SMALA_RS22640 901b075f06f1c923d5976d7f0eb627e3 437 Pfam PF00344 SecY translocase 73 420 7.5E-118 T 29-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 SMALA_RS22640 901b075f06f1c923d5976d7f0eb627e3 437 Hamap MF_01465 Protein translocase subunit SecY [secY]. 5 436 29.551 T 29-03-2018 IPR026593 Protein translocase subunit SecY SMALA_RS22255 47e7e8b97db47fa8159cbe4e813ec582 447 Pfam PF13796 Putative sensor 37 232 4.1E-45 T 29-03-2018 IPR025828 Putative sensor domain SMALA_RS22255 47e7e8b97db47fa8159cbe4e813ec582 447 SUPERFAMILY SSF55874 336 445 2.05E-12 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS22255 47e7e8b97db47fa8159cbe4e813ec582 447 Pfam PF07730 Histidine kinase 260 324 4.2E-14 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMALA_RS22255 47e7e8b97db47fa8159cbe4e813ec582 447 Gene3D G3DSA:3.30.565.10 330 447 2.6E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS23190 c8b5b7cb38aa59e595f64980c3117bee 317 SUPERFAMILY SSF51679 15 315 1.03E-68 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS23190 c8b5b7cb38aa59e595f64980c3117bee 317 Gene3D G3DSA:3.20.20.30 249 317 1.2E-7 T 29-03-2018 SMALA_RS23190 c8b5b7cb38aa59e595f64980c3117bee 317 TIGRFAM TIGR03619 F420_Rv2161c: probable F420-dependent oxidoreductase, Rv2161c family 39 288 1.7E-72 T 29-03-2018 IPR019921 Luciferase-like, F420-dependent oxidoreductase, Rv2161c, predicted SMALA_RS23190 c8b5b7cb38aa59e595f64980c3117bee 317 Gene3D G3DSA:3.20.20.30 10 248 1.4E-61 T 29-03-2018 SMALA_RS23190 c8b5b7cb38aa59e595f64980c3117bee 317 Pfam PF00296 Luciferase-like monooxygenase 12 244 2.2E-54 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS13065 d898816d778af24cc29e2005fa7451d1 146 SUPERFAMILY SSF81301 7 118 1.11E-34 T 29-03-2018 SMALA_RS13065 d898816d778af24cc29e2005fa7451d1 146 Pfam PF02410 Ribosomal silencing factor during starvation 14 109 1.4E-21 T 29-03-2018 SMALA_RS13065 d898816d778af24cc29e2005fa7451d1 146 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 7 110 22.418 T 29-03-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS SMALA_RS13065 d898816d778af24cc29e2005fa7451d1 146 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 11 109 4.6E-29 T 29-03-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS SMALA_RS13065 d898816d778af24cc29e2005fa7451d1 146 Gene3D G3DSA:3.30.460.10 5 125 4.4E-28 T 29-03-2018 SMALA_RS34680 f5ac20a3d39c9624fe9d9fd15b231c13 256 SUPERFAMILY SSF52266 10 192 2.0E-33 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain SMALA_RS34680 f5ac20a3d39c9624fe9d9fd15b231c13 256 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 12 183 4.0E-20 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain SMALA_RS34680 f5ac20a3d39c9624fe9d9fd15b231c13 256 Gene3D G3DSA:3.40.50.1110 2 198 3.6E-26 T 29-03-2018 SMALA_RS12925 7c3393c96c0903fd869773e278d935ce 306 Gene3D G3DSA:3.60.15.10 3 306 1.6E-54 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS12925 7c3393c96c0903fd869773e278d935ce 306 Pfam PF12706 Beta-lactamase superfamily domain 199 268 6.4E-11 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS12925 7c3393c96c0903fd869773e278d935ce 306 Hamap MF_01818 Ribonuclease BN [rbn]. 4 302 31.055 T 29-03-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 SMALA_RS12925 7c3393c96c0903fd869773e278d935ce 306 SUPERFAMILY SSF56281 5 300 3.01E-62 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS12925 7c3393c96c0903fd869773e278d935ce 306 Pfam PF00753 Metallo-beta-lactamase superfamily 20 123 5.2E-14 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS25575 9a6e90d18980f6ebe8ee7a58c29ec34b 308 SUPERFAMILY SSF161098 91 294 9.94E-17 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS25575 9a6e90d18980f6ebe8ee7a58c29ec34b 308 Gene3D G3DSA:1.10.3720.10 2 299 2.0E-40 T 29-03-2018 SMALA_RS25575 9a6e90d18980f6ebe8ee7a58c29ec34b 308 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 307 5.9E-35 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS01655 be0cc6e7bfdce73815e6c1d119aeefed 482 Gene3D G3DSA:3.40.605.10 3 272 5.0E-91 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS01655 be0cc6e7bfdce73815e6c1d119aeefed 482 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 282 293 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 SMALA_RS01655 be0cc6e7bfdce73815e6c1d119aeefed 482 Pfam PF00171 Aldehyde dehydrogenase family 17 478 1.6E-155 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS01655 be0cc6e7bfdce73815e6c1d119aeefed 482 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 254 261 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 SMALA_RS01655 be0cc6e7bfdce73815e6c1d119aeefed 482 SUPERFAMILY SSF53720 4 480 1.06E-152 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMALA_RS01655 be0cc6e7bfdce73815e6c1d119aeefed 482 Gene3D G3DSA:3.40.309.10 273 464 5.0E-65 T 29-03-2018 SMALA_RS24125 3c10137e2c4c5dc2f1d081ee97d91634 101 Pfam PF05121 Gas vesicle protein K 14 98 1.5E-37 T 29-03-2018 IPR007805 Gas vesicle protein GvpK GO:0031412 SMALA_RS10110 b292619855805869495fa3f253ee7ddf 436 Pfam PF01936 NYN domain 37 166 2.8E-11 T 29-03-2018 IPR021139 NYN domain, limkain-b1-type SMALA_RS10110 b292619855805869495fa3f253ee7ddf 436 Gene3D G3DSA:3.40.50.1010 1 176 1.5E-26 T 29-03-2018 IPR029060 PIN domain-like SMALA_RS11500 e8cdaa8b3d22998f9dac173e089fdb69 410 Pfam PF00067 Cytochrome P450 288 377 4.0E-16 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS11500 e8cdaa8b3d22998f9dac173e089fdb69 410 SUPERFAMILY SSF48264 10 409 2.1E-82 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS11500 e8cdaa8b3d22998f9dac173e089fdb69 410 PRINTS PR00359 B-class P450 signature 148 164 3.2E-45 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS11500 e8cdaa8b3d22998f9dac173e089fdb69 410 PRINTS PR00359 B-class P450 signature 165 180 3.2E-45 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS11500 e8cdaa8b3d22998f9dac173e089fdb69 410 PRINTS PR00359 B-class P450 signature 330 345 3.2E-45 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS11500 e8cdaa8b3d22998f9dac173e089fdb69 410 PRINTS PR00359 B-class P450 signature 207 229 3.2E-45 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS11500 e8cdaa8b3d22998f9dac173e089fdb69 410 PRINTS PR00359 B-class P450 signature 361 372 3.2E-45 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS11500 e8cdaa8b3d22998f9dac173e089fdb69 410 PRINTS PR00359 B-class P450 signature 352 361 3.2E-45 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS11500 e8cdaa8b3d22998f9dac173e089fdb69 410 PRINTS PR00359 B-class P450 signature 285 296 3.2E-45 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS11500 e8cdaa8b3d22998f9dac173e089fdb69 410 PRINTS PR00359 B-class P450 signature 302 329 3.2E-45 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS11500 e8cdaa8b3d22998f9dac173e089fdb69 410 PRINTS PR00359 B-class P450 signature 102 113 3.2E-45 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS11500 e8cdaa8b3d22998f9dac173e089fdb69 410 Gene3D G3DSA:1.10.630.10 11 410 9.4E-65 T 29-03-2018 SMALA_RS35260 0348034596778ce01b62aeb5bf3eff01 423 PIRSF PIRSF000136 3 243 2.3E-38 T 29-03-2018 IPR010031 L-gulonolactone/D-arabinono-1,4-lactone oxidase GO:0016899|GO:0055114 SMALA_RS35260 0348034596778ce01b62aeb5bf3eff01 423 PIRSF PIRSF000136 293 422 4.7E-5 T 29-03-2018 IPR010031 L-gulonolactone/D-arabinono-1,4-lactone oxidase GO:0016899|GO:0055114 SMALA_RS35260 0348034596778ce01b62aeb5bf3eff01 423 Gene3D G3DSA:3.30.465.10 69 195 1.2E-22 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SMALA_RS35260 0348034596778ce01b62aeb5bf3eff01 423 SUPERFAMILY SSF56176 5 179 3.27E-36 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SMALA_RS35260 0348034596778ce01b62aeb5bf3eff01 423 Gene3D G3DSA:3.30.43.10 2 66 5.9E-11 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 SMALA_RS35260 0348034596778ce01b62aeb5bf3eff01 423 Pfam PF04030 D-arabinono-1,4-lactone oxidase 293 418 2.6E-15 T 29-03-2018 IPR007173 D-arabinono-1,4-lactone oxidase GO:0003885|GO:0016020|GO:0055114 SMALA_RS35260 0348034596778ce01b62aeb5bf3eff01 423 Pfam PF01565 FAD binding domain 22 148 5.0E-20 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 SMALA_RS35260 0348034596778ce01b62aeb5bf3eff01 423 Gene3D G3DSA:3.40.462.10 298 385 4.1E-5 T 29-03-2018 IPR016170 Vanillyl-alcohol oxidase/Cytokinin dehydrogenase C-terminal domain SMALA_RS23220 acec760a8113fe02f603ee828d19f22b 483 Gene3D G3DSA:2.60.120.380 2 138 0.0041 T 29-03-2018 SMALA_RS23220 acec760a8113fe02f603ee828d19f22b 483 SMART SM00481 165 229 4.2E-5 T 29-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal SMALA_RS23220 acec760a8113fe02f603ee828d19f22b 483 Gene3D G3DSA:3.20.20.140 154 353 6.6E-27 T 29-03-2018 SMALA_RS23220 acec760a8113fe02f603ee828d19f22b 483 SUPERFAMILY SSF89550 162 368 2.62E-35 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 SMALA_RS24180 c4da7c3b5c75723adf068701405c9429 156 PIRSF PIRSF005384 5 154 2.3E-42 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 SMALA_RS24180 c4da7c3b5c75723adf068701405c9429 156 SUPERFAMILY SSF89623 4 151 5.49E-46 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 SMALA_RS24180 c4da7c3b5c75723adf068701405c9429 156 Pfam PF02502 Ribose/Galactose Isomerase 7 145 2.7E-42 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 SMALA_RS24180 c4da7c3b5c75723adf068701405c9429 156 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 7 151 4.5E-32 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 SMALA_RS24180 c4da7c3b5c75723adf068701405c9429 156 TIGRFAM TIGR02133 RPI_actino: ribose 5-phosphate isomerase 5 152 2.7E-64 T 29-03-2018 IPR011860 Ribose 5-phosphate isomerase GO:0004751 SMALA_RS24180 c4da7c3b5c75723adf068701405c9429 156 Gene3D G3DSA:3.40.1400.10 3 156 4.5E-52 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 SMALA_RS16720 078715307fb0f2ef4093fe18fe3a2342 320 Pfam PF03631 Virulence factor BrkB 33 279 9.6E-47 T 29-03-2018 IPR017039 Virulence factor BrkB SMALA_RS16720 078715307fb0f2ef4093fe18fe3a2342 320 PIRSF PIRSF035875 14 300 4.8E-25 T 29-03-2018 IPR017039 Virulence factor BrkB SMALA_RS03370 241a97510f861d45d6f472a5db5c6596 202 PIRSF PIRSF000847 11 202 2.7E-43 T 29-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 SMALA_RS03370 241a97510f861d45d6f472a5db5c6596 202 Pfam PF01066 CDP-alcohol phosphatidyltransferase 16 85 9.2E-14 T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 SMALA_RS03370 241a97510f861d45d6f472a5db5c6596 202 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 63 85 - T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 SMALA_RS22290 0a7b7b803494f44733d1f27adade354f 199 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 35 177 8.7E-32 T 29-03-2018 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS29605 c74d2d044c4c6ff2e7bbd65eded44b15 328 Gene3D G3DSA:1.10.10.60 234 273 8.4E-14 T 29-03-2018 SMALA_RS29605 c74d2d044c4c6ff2e7bbd65eded44b15 328 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 269 311 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 SMALA_RS29605 c74d2d044c4c6ff2e7bbd65eded44b15 328 Pfam PF12833 Helix-turn-helix domain 238 316 8.7E-21 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS29605 c74d2d044c4c6ff2e7bbd65eded44b15 328 SUPERFAMILY SSF46689 217 266 1.08E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS29605 c74d2d044c4c6ff2e7bbd65eded44b15 328 SUPERFAMILY SSF52317 1 198 2.44E-39 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS29605 c74d2d044c4c6ff2e7bbd65eded44b15 328 SUPERFAMILY SSF46689 269 319 1.76E-9 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS29605 c74d2d044c4c6ff2e7bbd65eded44b15 328 Gene3D G3DSA:1.10.10.60 274 327 1.1E-14 T 29-03-2018 SMALA_RS29605 c74d2d044c4c6ff2e7bbd65eded44b15 328 SMART SM00342 232 315 4.2E-28 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS29605 c74d2d044c4c6ff2e7bbd65eded44b15 328 Pfam PF01965 DJ-1/PfpI family 89 177 2.8E-9 T 29-03-2018 IPR002818 DJ-1/PfpI SMALA_RS29605 c74d2d044c4c6ff2e7bbd65eded44b15 328 Gene3D G3DSA:3.40.50.880 1 233 1.6E-55 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS29860 1eef4145764fb38717fc8cf390ee4627 484 SUPERFAMILY SSF103473 272 482 3.4E-61 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS29860 1eef4145764fb38717fc8cf390ee4627 484 SUPERFAMILY SSF103473 16 219 3.4E-61 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS29860 1eef4145764fb38717fc8cf390ee4627 484 Pfam PF07690 Major Facilitator Superfamily 35 311 1.7E-22 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS29860 1eef4145764fb38717fc8cf390ee4627 484 Gene3D G3DSA:1.20.1250.20 23 228 1.7E-27 T 29-03-2018 SMALA_RS29860 1eef4145764fb38717fc8cf390ee4627 484 Gene3D G3DSA:1.20.1250.20 281 484 1.1E-33 T 29-03-2018 SMALA_RS37285 fecfcb6e28a339afad17c5112650e0b0 417 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 116 124 7.9E-14 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMALA_RS37285 fecfcb6e28a339afad17c5112650e0b0 417 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 211 227 7.9E-14 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMALA_RS37285 fecfcb6e28a339afad17c5112650e0b0 417 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 12 34 7.9E-14 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMALA_RS37285 fecfcb6e28a339afad17c5112650e0b0 417 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 284 302 7.9E-14 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMALA_RS37285 fecfcb6e28a339afad17c5112650e0b0 417 Gene3D G3DSA:3.50.50.60 1 145 6.0E-20 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS37285 fecfcb6e28a339afad17c5112650e0b0 417 Gene3D G3DSA:3.50.50.60 199 321 1.9E-13 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS37285 fecfcb6e28a339afad17c5112650e0b0 417 Gene3D G3DSA:3.50.50.60 146 198 2.2E-5 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS37285 fecfcb6e28a339afad17c5112650e0b0 417 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 13 32 2.7E-11 T 29-03-2018 SMALA_RS37285 fecfcb6e28a339afad17c5112650e0b0 417 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 115 133 2.7E-11 T 29-03-2018 SMALA_RS37285 fecfcb6e28a339afad17c5112650e0b0 417 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 274 296 2.7E-11 T 29-03-2018 SMALA_RS37285 fecfcb6e28a339afad17c5112650e0b0 417 SUPERFAMILY SSF51905 3 320 2.83E-36 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS37285 fecfcb6e28a339afad17c5112650e0b0 417 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 12 302 1.9E-25 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS40270 7584191c4ff49f99f30b0ccc587cfb87 212 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 39 186 1.1E-21 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 SMALA_RS40270 7584191c4ff49f99f30b0ccc587cfb87 212 SMART SM00644 27 186 2.9E-18 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 SMALA_RS40270 7584191c4ff49f99f30b0ccc587cfb87 212 SUPERFAMILY SSF55846 18 201 1.19E-23 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 SMALA_RS40270 7584191c4ff49f99f30b0ccc587cfb87 212 Gene3D G3DSA:3.40.80.10 18 201 8.3E-33 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 SMALA_RS12785 ea19eb2a50b8a5db9ff070a0ee5a164a 249 SUPERFAMILY SSF50249 1 69 2.4E-18 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMALA_RS12785 ea19eb2a50b8a5db9ff070a0ee5a164a 249 Hamap MF_00201 DNA repair protein RecO [recO]. 2 249 26.164 T 29-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 SMALA_RS12785 ea19eb2a50b8a5db9ff070a0ee5a164a 249 SUPERFAMILY SSF57863 90 239 1.23E-39 T 29-03-2018 SMALA_RS12785 ea19eb2a50b8a5db9ff070a0ee5a164a 249 Gene3D G3DSA:2.40.50.140 1 88 3.6E-28 T 29-03-2018 SMALA_RS12785 ea19eb2a50b8a5db9ff070a0ee5a164a 249 TIGRFAM TIGR00613 reco: DNA repair protein RecO 5 216 1.3E-34 T 29-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 SMALA_RS12785 ea19eb2a50b8a5db9ff070a0ee5a164a 249 Pfam PF11967 Recombination protein O N terminal 1 86 4.5E-28 T 29-03-2018 IPR022572 DNA replication/recombination mediator RecO, N-terminal SMALA_RS12785 ea19eb2a50b8a5db9ff070a0ee5a164a 249 Pfam PF02565 Recombination protein O C terminal 92 245 3.9E-34 T 29-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 SMALA_RS37080 e33f9ef59dbea5e2a01870c79f10a0bb 445 Gene3D G3DSA:1.10.260.40 18 96 0.0016 T 29-03-2018 SMALA_RS37080 e33f9ef59dbea5e2a01870c79f10a0bb 445 Gene3D G3DSA:1.25.40.10 122 444 3.4E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS37080 e33f9ef59dbea5e2a01870c79f10a0bb 445 SUPERFAMILY SSF48452 217 415 2.07E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS21700 4ab0a94fabd13bbab4d4b9fff9300f3f 616 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 4 611 45.043 T 29-03-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 SMALA_RS21700 4ab0a94fabd13bbab4d4b9fff9300f3f 616 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 18 611 4.0E-238 T 29-03-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 SMALA_RS21700 4ab0a94fabd13bbab4d4b9fff9300f3f 616 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 514 525 - T 29-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 SMALA_RS21700 4ab0a94fabd13bbab4d4b9fff9300f3f 616 Pfam PF00920 Dehydratase family 34 608 1.8E-214 T 29-03-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 SMALA_RS21700 4ab0a94fabd13bbab4d4b9fff9300f3f 616 SUPERFAMILY SSF52016 426 612 2.35E-61 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel SMALA_RS21700 4ab0a94fabd13bbab4d4b9fff9300f3f 616 Gene3D G3DSA:3.40.50.2300 16 253 1.1E-4 T 29-03-2018 SMALA_RS21700 4ab0a94fabd13bbab4d4b9fff9300f3f 616 SUPERFAMILY SSF143975 4 425 7.19E-132 T 29-03-2018 SMALA_RS21700 4ab0a94fabd13bbab4d4b9fff9300f3f 616 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 122 132 - T 29-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 SMALA_RS00360 b7e7039b7e03e364226643e5de45843b 229 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 84 223 4.6E-20 T 29-03-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 SMALA_RS00360 b7e7039b7e03e364226643e5de45843b 229 SUPERFAMILY SSF46689 17 81 3.69E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS00360 b7e7039b7e03e364226643e5de45843b 229 ProSitePatterns PS01081 TetR-type HTH domain signature. 39 70 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site SMALA_RS00360 b7e7039b7e03e364226643e5de45843b 229 Gene3D G3DSA:1.10.357.10 83 225 6.8E-30 T 29-03-2018 SMALA_RS00360 b7e7039b7e03e364226643e5de45843b 229 PRINTS PR00400 Tetracycline repressor protein signature 39 62 2.2E-9 T 29-03-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 SMALA_RS00360 b7e7039b7e03e364226643e5de45843b 229 PRINTS PR00400 Tetracycline repressor protein signature 91 110 2.2E-9 T 29-03-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 SMALA_RS00360 b7e7039b7e03e364226643e5de45843b 229 PRINTS PR00400 Tetracycline repressor protein signature 208 222 2.2E-9 T 29-03-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 SMALA_RS00360 b7e7039b7e03e364226643e5de45843b 229 Gene3D G3DSA:1.10.10.60 4 77 3.8E-17 T 29-03-2018 SMALA_RS00360 b7e7039b7e03e364226643e5de45843b 229 SUPERFAMILY SSF48498 87 223 1.33E-28 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS00360 b7e7039b7e03e364226643e5de45843b 229 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 71 2.2E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS00360 b7e7039b7e03e364226643e5de45843b 229 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 48 71 5.7E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS00360 b7e7039b7e03e364226643e5de45843b 229 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 40 5.7E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS00285 41f4f84788427c8c0d817b6de6dc8168 189 Gene3D G3DSA:1.10.357.10 62 189 2.4E-11 T 29-03-2018 SMALA_RS00285 41f4f84788427c8c0d817b6de6dc8168 189 SUPERFAMILY SSF46689 10 70 7.98E-10 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS00285 41f4f84788427c8c0d817b6de6dc8168 189 SUPERFAMILY SSF48498 78 184 1.02E-13 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS00285 41f4f84788427c8c0d817b6de6dc8168 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 62 1.2E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS00285 41f4f84788427c8c0d817b6de6dc8168 189 Pfam PF16859 Bacterial transcriptional repressor C-terminal 78 179 2.3E-15 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS00285 41f4f84788427c8c0d817b6de6dc8168 189 Gene3D G3DSA:1.10.10.60 9 61 7.2E-11 T 29-03-2018 SMALA_RS18680 0ac67045d6cbadf1c4ffbcd663a9df73 752 Pfam PF00912 Transglycosylase 77 261 7.1E-63 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 SMALA_RS18680 0ac67045d6cbadf1c4ffbcd663a9df73 752 Gene3D G3DSA:3.40.710.10 293 720 1.5E-98 T 29-03-2018 SMALA_RS18680 0ac67045d6cbadf1c4ffbcd663a9df73 752 SUPERFAMILY SSF53955 63 284 1.97E-68 T 29-03-2018 IPR023346 Lysozyme-like domain SMALA_RS18680 0ac67045d6cbadf1c4ffbcd663a9df73 752 Pfam PF00905 Penicillin binding protein transpeptidase domain 362 630 7.6E-32 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 SMALA_RS18680 0ac67045d6cbadf1c4ffbcd663a9df73 752 SUPERFAMILY SSF56601 243 265 2.14E-95 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMALA_RS18680 0ac67045d6cbadf1c4ffbcd663a9df73 752 SUPERFAMILY SSF56601 299 680 2.14E-95 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMALA_RS18680 0ac67045d6cbadf1c4ffbcd663a9df73 752 Gene3D G3DSA:1.10.3810.10 68 280 4.3E-74 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 SMALA_RS10905 9019be028189e531e40507e7972140c0 219 ProDom PD037769 DNA-BINDING YHEO UNCHARACTERIZED BACTERIA SIMILAR HI0575 CONTAINING TRANSCRIPTION REGULATOR HELIX-TURN-HELIX 18 138 6.0E-43 T 29-03-2018 IPR013559 YheO-like SMALA_RS10905 9019be028189e531e40507e7972140c0 219 Pfam PF13309 HTH domain 156 217 1.5E-18 T 29-03-2018 SMALA_RS10905 9019be028189e531e40507e7972140c0 219 Gene3D G3DSA:1.10.10.60 149 219 3.3E-5 T 29-03-2018 SMALA_RS10905 9019be028189e531e40507e7972140c0 219 Pfam PF08348 YheO-like PAS domain 19 128 1.2E-30 T 29-03-2018 IPR013559 YheO-like SMALA_RS37225 7fd38e8bd80978d891d3d3a96bd6512b 935 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 906 918 3.1E-6 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS37225 7fd38e8bd80978d891d3d3a96bd6512b 935 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 890 906 3.1E-6 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS37225 7fd38e8bd80978d891d3d3a96bd6512b 935 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 876 890 3.1E-6 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS37225 7fd38e8bd80978d891d3d3a96bd6512b 935 Pfam PF13191 AAA ATPase domain 2 165 4.1E-21 T 29-03-2018 SMALA_RS37225 7fd38e8bd80978d891d3d3a96bd6512b 935 Gene3D G3DSA:3.40.50.300 1 179 2.4E-8 T 29-03-2018 SMALA_RS37225 7fd38e8bd80978d891d3d3a96bd6512b 935 Gene3D G3DSA:1.25.40.10 570 885 5.1E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS37225 7fd38e8bd80978d891d3d3a96bd6512b 935 SUPERFAMILY SSF52540 133 250 2.96E-10 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS37225 7fd38e8bd80978d891d3d3a96bd6512b 935 SUPERFAMILY SSF52540 5 80 2.96E-10 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS37225 7fd38e8bd80978d891d3d3a96bd6512b 935 SUPERFAMILY SSF46894 868 934 8.16E-14 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS37225 7fd38e8bd80978d891d3d3a96bd6512b 935 Pfam PF00196 Bacterial regulatory proteins, luxR family 875 929 2.0E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS37225 7fd38e8bd80978d891d3d3a96bd6512b 935 Gene3D G3DSA:1.25.40.120 255 423 0.059 T 29-03-2018 SMALA_RS37225 7fd38e8bd80978d891d3d3a96bd6512b 935 SMART SM00421 873 930 5.1E-16 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS37225 7fd38e8bd80978d891d3d3a96bd6512b 935 Gene3D G3DSA:1.10.10.10 886 935 3.2E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS34930 969d25c25c0a0a3a410cfbccadae81f1 230 SUPERFAMILY SSF55874 124 226 4.25E-10 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS34930 969d25c25c0a0a3a410cfbccadae81f1 230 Gene3D G3DSA:3.30.565.10 94 230 2.0E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS34930 969d25c25c0a0a3a410cfbccadae81f1 230 Pfam PF13581 Histidine kinase-like ATPase domain 103 221 4.8E-14 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS25825 d7e75609cb6d2efd721edfc6040bb6f9 562 SUPERFAMILY SSF50156 448 555 2.76E-17 T 29-03-2018 IPR001478 PDZ domain GO:0005515 SMALA_RS25825 d7e75609cb6d2efd721edfc6040bb6f9 562 PRINTS PR00834 HtrA/DegQ protease family signature 282 294 4.4E-44 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMALA_RS25825 d7e75609cb6d2efd721edfc6040bb6f9 562 PRINTS PR00834 HtrA/DegQ protease family signature 347 371 4.4E-44 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMALA_RS25825 d7e75609cb6d2efd721edfc6040bb6f9 562 PRINTS PR00834 HtrA/DegQ protease family signature 412 429 4.4E-44 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMALA_RS25825 d7e75609cb6d2efd721edfc6040bb6f9 562 PRINTS PR00834 HtrA/DegQ protease family signature 306 326 4.4E-44 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMALA_RS25825 d7e75609cb6d2efd721edfc6040bb6f9 562 PRINTS PR00834 HtrA/DegQ protease family signature 390 407 4.4E-44 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMALA_RS25825 d7e75609cb6d2efd721edfc6040bb6f9 562 PRINTS PR00834 HtrA/DegQ protease family signature 505 517 4.4E-44 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMALA_RS25825 d7e75609cb6d2efd721edfc6040bb6f9 562 SUPERFAMILY SSF50494 242 472 5.33E-56 T 29-03-2018 IPR009003 Peptidase S1, PA clan SMALA_RS25825 d7e75609cb6d2efd721edfc6040bb6f9 562 Gene3D G3DSA:2.40.10.10 243 347 4.7E-31 T 29-03-2018 SMALA_RS25825 d7e75609cb6d2efd721edfc6040bb6f9 562 Gene3D G3DSA:2.40.10.10 348 460 4.7E-38 T 29-03-2018 SMALA_RS25825 d7e75609cb6d2efd721edfc6040bb6f9 562 Pfam PF13365 Trypsin-like peptidase domain 273 419 7.7E-35 T 29-03-2018 SMALA_RS25825 d7e75609cb6d2efd721edfc6040bb6f9 562 Gene3D G3DSA:2.30.42.10 461 562 1.5E-16 T 29-03-2018 SMALA_RS25825 d7e75609cb6d2efd721edfc6040bb6f9 562 SMART SM00228 467 547 6.9E-5 T 29-03-2018 IPR001478 PDZ domain GO:0005515 SMALA_RS25825 d7e75609cb6d2efd721edfc6040bb6f9 562 Pfam PF13180 PDZ domain 467 556 5.2E-19 T 29-03-2018 IPR001478 PDZ domain GO:0005515 SMALA_RS27975 83e927e5f676a9d302f7efa43154e8e6 279 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 20 271 1.8E-93 T 29-03-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 SMALA_RS27975 83e927e5f676a9d302f7efa43154e8e6 279 Gene3D G3DSA:3.40.1190.20 16 278 1.5E-60 T 29-03-2018 IPR029056 Ribokinase-like SMALA_RS27975 83e927e5f676a9d302f7efa43154e8e6 279 Pfam PF08543 Phosphomethylpyrimidine kinase 27 270 1.8E-90 T 29-03-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 SMALA_RS27975 83e927e5f676a9d302f7efa43154e8e6 279 SUPERFAMILY SSF53613 19 274 2.81E-77 T 29-03-2018 IPR029056 Ribokinase-like SMALA_RS04865 b4d2786b7e60bca316c0017ed24a882a 161 Pfam PF07883 Cupin domain 68 134 3.9E-8 T 29-03-2018 IPR013096 Cupin 2, conserved barrel SMALA_RS04865 b4d2786b7e60bca316c0017ed24a882a 161 SUPERFAMILY SSF51182 37 142 1.93E-19 T 29-03-2018 IPR011051 RmlC-like cupin domain SMALA_RS04865 b4d2786b7e60bca316c0017ed24a882a 161 Gene3D G3DSA:2.60.120.10 11 145 1.3E-15 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SMALA_RS39865 2303caff394f1d268fce26b6297cd782 164 Pfam PF01613 Flavin reductase like domain 1 142 1.4E-31 T 29-03-2018 IPR002563 Flavin reductase like domain GO:0010181 SMALA_RS39865 2303caff394f1d268fce26b6297cd782 164 SMART SM00903 1 143 1.7E-48 T 29-03-2018 IPR002563 Flavin reductase like domain GO:0010181 SMALA_RS39865 2303caff394f1d268fce26b6297cd782 164 Gene3D G3DSA:2.30.110.10 1 144 1.0E-39 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS39865 2303caff394f1d268fce26b6297cd782 164 SUPERFAMILY SSF50475 2 143 6.38E-41 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS34950 6db72879c234f29c8d522c61a776215e 203 SUPERFAMILY SSF48498 81 199 1.13E-27 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS34950 6db72879c234f29c8d522c61a776215e 203 Gene3D G3DSA:1.10.357.10 68 203 1.4E-25 T 29-03-2018 SMALA_RS34950 6db72879c234f29c8d522c61a776215e 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 4.3E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS34950 6db72879c234f29c8d522c61a776215e 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 4.3E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS34950 6db72879c234f29c8d522c61a776215e 203 SUPERFAMILY SSF46689 16 72 2.98E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS34950 6db72879c234f29c8d522c61a776215e 203 Pfam PF16859 Bacterial transcriptional repressor C-terminal 80 191 2.5E-33 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS34950 6db72879c234f29c8d522c61a776215e 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 69 7.6E-14 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS34950 6db72879c234f29c8d522c61a776215e 203 Gene3D G3DSA:1.10.10.60 1 67 7.0E-17 T 29-03-2018 SMALA_RS38280 fe96d22d874aa6a304c7bb52ce05b663 437 SUPERFAMILY SSF55874 331 435 4.06E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS38280 fe96d22d874aa6a304c7bb52ce05b663 437 Pfam PF07730 Histidine kinase 249 315 4.3E-15 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMALA_RS38280 fe96d22d874aa6a304c7bb52ce05b663 437 Gene3D G3DSA:3.30.565.10 225 437 7.2E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS38280 fe96d22d874aa6a304c7bb52ce05b663 437 SMART SM00387 349 437 0.0029 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS15055 aea6424cb01a30f6edd68baf9542913b 471 Pfam PF00324 Amino acid permease 19 447 1.5E-108 T 29-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 SMALA_RS15055 aea6424cb01a30f6edd68baf9542913b 471 PIRSF PIRSF006060 4 466 1.8E-62 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMALA_RS13835 aedf84a79e67fa7f02bb35a20386bbae 253 SUPERFAMILY SSF53474 9 248 2.13E-49 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS13835 aedf84a79e67fa7f02bb35a20386bbae 253 Pfam PF00975 Thioesterase domain 23 244 2.7E-52 T 29-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 SMALA_RS13835 aedf84a79e67fa7f02bb35a20386bbae 253 Gene3D G3DSA:3.40.50.1820 2 251 3.3E-38 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS13835 aedf84a79e67fa7f02bb35a20386bbae 253 SMART SM00824 Thioesterase 25 248 0.0013 T 29-03-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 SMALA_RS33200 77bfd454a67cc0f29d20b53d81673813 194 SUPERFAMILY SSF46689 4 73 3.29E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS33200 77bfd454a67cc0f29d20b53d81673813 194 Gene3D G3DSA:1.10.357.10 72 190 5.7E-21 T 29-03-2018 SMALA_RS33200 77bfd454a67cc0f29d20b53d81673813 194 Gene3D G3DSA:1.10.10.60 3 71 3.8E-21 T 29-03-2018 SMALA_RS33200 77bfd454a67cc0f29d20b53d81673813 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 62 8.4E-16 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS33200 77bfd454a67cc0f29d20b53d81673813 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 9.0E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS33200 77bfd454a67cc0f29d20b53d81673813 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 9.0E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS03930 39e1a37c7e4a7a863fa1d4eba20d8f06 409 SUPERFAMILY SSF53067 85 217 8.16E-12 T 29-03-2018 SMALA_RS03930 39e1a37c7e4a7a863fa1d4eba20d8f06 409 Gene3D G3DSA:1.10.10.10 6 75 1.6E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS03930 39e1a37c7e4a7a863fa1d4eba20d8f06 409 Pfam PF00480 ROK family 97 394 2.6E-31 T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 SMALA_RS03930 39e1a37c7e4a7a863fa1d4eba20d8f06 409 Gene3D G3DSA:3.30.420.40 76 217 8.7E-21 T 29-03-2018 SMALA_RS03930 39e1a37c7e4a7a863fa1d4eba20d8f06 409 Gene3D G3DSA:3.30.420.40 218 407 2.2E-41 T 29-03-2018 SMALA_RS03930 39e1a37c7e4a7a863fa1d4eba20d8f06 409 SUPERFAMILY SSF53067 226 403 2.3E-32 T 29-03-2018 SMALA_RS19320 a4cbe49ab5d02a541607f8553da54046 426 SUPERFAMILY SSF46589 2 111 5.23E-23 T 29-03-2018 IPR010978 tRNA-binding arm GO:0000166 SMALA_RS19320 a4cbe49ab5d02a541607f8553da54046 426 SUPERFAMILY SSF55681 132 416 3.32E-84 T 29-03-2018 SMALA_RS19320 a4cbe49ab5d02a541607f8553da54046 426 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 222 397 5.2E-28 T 29-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMALA_RS19320 a4cbe49ab5d02a541607f8553da54046 426 PIRSF PIRSF001529 1 423 5.4E-140 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 SMALA_RS19320 a4cbe49ab5d02a541607f8553da54046 426 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 419 38.812 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 SMALA_RS19320 a4cbe49ab5d02a541607f8553da54046 426 TIGRFAM TIGR00414 serS: serine--tRNA ligase 2 414 3.4E-133 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 SMALA_RS19320 a4cbe49ab5d02a541607f8553da54046 426 PRINTS PR00981 Seryl-tRNA synthetase signature 315 328 2.6E-30 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 SMALA_RS19320 a4cbe49ab5d02a541607f8553da54046 426 PRINTS PR00981 Seryl-tRNA synthetase signature 332 348 2.6E-30 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 SMALA_RS19320 a4cbe49ab5d02a541607f8553da54046 426 PRINTS PR00981 Seryl-tRNA synthetase signature 275 288 2.6E-30 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 SMALA_RS19320 a4cbe49ab5d02a541607f8553da54046 426 PRINTS PR00981 Seryl-tRNA synthetase signature 263 275 2.6E-30 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 SMALA_RS19320 a4cbe49ab5d02a541607f8553da54046 426 PRINTS PR00981 Seryl-tRNA synthetase signature 350 366 2.6E-30 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 SMALA_RS19320 a4cbe49ab5d02a541607f8553da54046 426 Gene3D G3DSA:3.30.930.10 104 425 1.0E-86 T 29-03-2018 SMALA_RS19320 a4cbe49ab5d02a541607f8553da54046 426 Gene3D G3DSA:1.10.287.40 1 102 1.9E-19 T 29-03-2018 SMALA_RS19320 a4cbe49ab5d02a541607f8553da54046 426 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 106 6.2E-23 T 29-03-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 SMALA_RS26905 4b6d5a6ee09db2448e300a09d03838da 271 Pfam PF00213 ATP synthase delta (OSCP) subunit 109 268 4.4E-31 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMALA_RS26905 4b6d5a6ee09db2448e300a09d03838da 271 Hamap MF_01416 ATP synthase subunit delta [atpD]. 94 271 14.665 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMALA_RS26905 4b6d5a6ee09db2448e300a09d03838da 271 Gene3D G3DSA:1.10.520.20 108 200 1.0E-14 T 29-03-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMALA_RS26905 4b6d5a6ee09db2448e300a09d03838da 271 Gene3D G3DSA:1.10.520.20 10 107 1.2E-11 T 29-03-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMALA_RS26905 4b6d5a6ee09db2448e300a09d03838da 271 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 111 267 1.6E-20 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMALA_RS26905 4b6d5a6ee09db2448e300a09d03838da 271 PRINTS PR00125 ATP synthase delta subunit signature 244 262 4.8E-7 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMALA_RS26905 4b6d5a6ee09db2448e300a09d03838da 271 PRINTS PR00125 ATP synthase delta subunit signature 229 244 4.8E-7 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMALA_RS03260 7747c41fc8e0bb567d048fe58c727a2c 442 Pfam PF00155 Aminotransferase class I and II 114 428 9.9E-21 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMALA_RS03260 7747c41fc8e0bb567d048fe58c727a2c 442 SUPERFAMILY SSF46785 12 78 3.63E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS03260 7747c41fc8e0bb567d048fe58c727a2c 442 SMART SM00345 15 74 8.2E-12 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS03260 7747c41fc8e0bb567d048fe58c727a2c 442 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 3.7E-13 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS03260 7747c41fc8e0bb567d048fe58c727a2c 442 Gene3D G3DSA:1.10.10.10 8 86 1.2E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS03260 7747c41fc8e0bb567d048fe58c727a2c 442 Gene3D G3DSA:3.40.640.10 116 324 5.9E-31 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS03260 7747c41fc8e0bb567d048fe58c727a2c 442 SUPERFAMILY SSF53383 70 432 1.18E-56 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS03260 7747c41fc8e0bb567d048fe58c727a2c 442 Gene3D G3DSA:3.90.1150.10 325 438 3.4E-15 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS12545 fe02c2a71ef6abeae9b4694366ce5daf 184 Gene3D G3DSA:2.60.130.10 1 183 1.5E-51 T 29-03-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 SMALA_RS12545 fe02c2a71ef6abeae9b4694366ce5daf 184 Pfam PF00775 Dioxygenase 24 108 2.8E-9 T 29-03-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 SMALA_RS12545 fe02c2a71ef6abeae9b4694366ce5daf 184 SUPERFAMILY SSF49482 1 182 7.06E-40 T 29-03-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 SMALA_RS12545 fe02c2a71ef6abeae9b4694366ce5daf 184 TIGRFAM TIGR02423 protocat_alph: protocatechuate 3,4-dioxygenase, alpha subunit 1 182 3.7E-47 T 29-03-2018 IPR012786 Protocatechuate 3,4-dioxygenase, alpha subunit GO:0005506|GO:0018578|GO:0019439|GO:0055114 KEGG: 00362+1.13.11.3|KEGG: 00624+1.13.11.3 SMALA_RS16540 e90f0fbbe6e2d438e909d0b7eae8cd03 310 SUPERFAMILY SSF51569 10 290 7.45E-86 T 29-03-2018 SMALA_RS16540 e90f0fbbe6e2d438e909d0b7eae8cd03 310 Gene3D G3DSA:3.20.20.70 8 277 8.2E-81 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS16540 e90f0fbbe6e2d438e909d0b7eae8cd03 310 Pfam PF03102 NeuB family 41 277 3.1E-81 T 29-03-2018 IPR013132 N-acetylneuraminic acid synthase, N-terminal GO:0016051 Reactome: R-HSA-4085001 SMALA_RS26325 2a9d5c01afbe66b3eeb01b9db64fa020 489 SMART SM00387 382 486 5.9E-9 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS26325 2a9d5c01afbe66b3eeb01b9db64fa020 489 SUPERFAMILY SSF55874 361 484 6.42E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS26325 2a9d5c01afbe66b3eeb01b9db64fa020 489 Gene3D G3DSA:3.30.450.20 137 280 1.1E-10 T 29-03-2018 SMALA_RS26325 2a9d5c01afbe66b3eeb01b9db64fa020 489 Pfam PF12282 Signal transduction histidine kinase 1 144 4.4E-60 T 29-03-2018 IPR022066 Signal transduction histidine kinase SMALA_RS26325 2a9d5c01afbe66b3eeb01b9db64fa020 489 SUPERFAMILY SSF55785 173 281 2.09E-5 T 29-03-2018 IPR000014 PAS domain SMALA_RS26325 2a9d5c01afbe66b3eeb01b9db64fa020 489 SMART SM00911 290 372 0.0086 T 29-03-2018 IPR011102 Signal transduction histidine kinase, HWE region GO:0004673 SMALA_RS26325 2a9d5c01afbe66b3eeb01b9db64fa020 489 Pfam PF07568 Histidine kinase 290 360 6.1E-22 T 29-03-2018 IPR011495 Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain SMALA_RS26325 2a9d5c01afbe66b3eeb01b9db64fa020 489 Pfam PF08448 PAS fold 172 276 3.0E-13 T 29-03-2018 IPR013656 PAS fold-4 SMALA_RS26325 2a9d5c01afbe66b3eeb01b9db64fa020 489 Gene3D G3DSA:3.30.565.10 281 485 1.4E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS26325 2a9d5c01afbe66b3eeb01b9db64fa020 489 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 385 484 2.2E-10 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS09265 b9a35bd4058bf646eea27687eb4b65f8 527 SUPERFAMILY SSF53720 22 519 4.58E-82 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMALA_RS09265 b9a35bd4058bf646eea27687eb4b65f8 527 Gene3D G3DSA:3.40.309.10 272 464 4.8E-26 T 29-03-2018 SMALA_RS09265 b9a35bd4058bf646eea27687eb4b65f8 527 Pfam PF00171 Aldehyde dehydrogenase family 21 462 1.5E-41 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS09265 b9a35bd4058bf646eea27687eb4b65f8 527 Gene3D G3DSA:3.40.605.10 2 271 1.6E-46 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS33070 2d09e7c26ec1b4a09daa248716f54895 147 Hamap MF_00073 N utilization substance protein B homolog [nusB]. 2 137 22.956 T 29-03-2018 IPR011605 NusB antitermination factor GO:0006353 SMALA_RS33070 2d09e7c26ec1b4a09daa248716f54895 147 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 4 133 8.9E-41 T 29-03-2018 IPR011605 NusB antitermination factor GO:0006353 SMALA_RS33070 2d09e7c26ec1b4a09daa248716f54895 147 Pfam PF01029 NusB family 6 132 1.5E-36 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 SMALA_RS33070 2d09e7c26ec1b4a09daa248716f54895 147 SUPERFAMILY SSF48013 4 132 1.7E-40 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 SMALA_RS33070 2d09e7c26ec1b4a09daa248716f54895 147 Gene3D G3DSA:1.10.940.10 1 147 1.3E-42 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 SMALA_RS22130 b1373fe3dffad54440675ed7af1586b6 460 Pfam PF10531 SLBB domain 262 308 2.7E-8 T 29-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS22130 b1373fe3dffad54440675ed7af1586b6 460 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 359 370 - T 29-03-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS22130 b1373fe3dffad54440675ed7af1586b6 460 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 348 431 3.4E-33 T 29-03-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS22130 b1373fe3dffad54440675ed7af1586b6 460 SUPERFAMILY SSF140490 342 441 2.09E-38 T 29-03-2018 SMALA_RS22130 b1373fe3dffad54440675ed7af1586b6 460 SUPERFAMILY SSF142984 260 341 1.57E-21 T 29-03-2018 SMALA_RS22130 b1373fe3dffad54440675ed7af1586b6 460 Gene3D G3DSA:3.10.560.10 255 355 2.8E-4 T 29-03-2018 SMALA_RS22130 b1373fe3dffad54440675ed7af1586b6 460 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 59 237 1.8E-46 T 29-03-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS22130 b1373fe3dffad54440675ed7af1586b6 460 SUPERFAMILY SSF142019 18 257 4.45E-80 T 29-03-2018 SMALA_RS22130 b1373fe3dffad54440675ed7af1586b6 460 TIGRFAM TIGR01959 nuoF_fam: NADH oxidoreductase (quinone), F subunit 22 432 3.1E-185 T 29-03-2018 IPR011537 NADH ubiquinone oxidoreductase, F subunit GO:0010181|GO:0016651|GO:0051287|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS22130 b1373fe3dffad54440675ed7af1586b6 460 SMART SM00928 346 391 9.2E-27 T 29-03-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS22130 b1373fe3dffad54440675ed7af1586b6 460 ProSitePatterns PS00644 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. 185 200 - T 29-03-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS00910 20505851782bda00ca1de374ae6c1f91 525 PIRSF PIRSF002741 24 519 6.4E-69 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 SMALA_RS00910 20505851782bda00ca1de374ae6c1f91 525 SUPERFAMILY SSF53850 54 514 1.81E-98 T 29-03-2018 SMALA_RS00910 20505851782bda00ca1de374ae6c1f91 525 Gene3D G3DSA:3.90.76.10 72 173 1.3E-27 T 29-03-2018 SMALA_RS00910 20505851782bda00ca1de374ae6c1f91 525 Gene3D G3DSA:3.10.105.10 306 497 1.2E-28 T 29-03-2018 SMALA_RS00910 20505851782bda00ca1de374ae6c1f91 525 Gene3D G3DSA:3.40.190.10 174 305 4.9E-28 T 29-03-2018 SMALA_RS00910 20505851782bda00ca1de374ae6c1f91 525 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 99 408 3.0E-64 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain SMALA_RS18050 0ae0eb48803078d756e955cbd52da7cd 342 Gene3D G3DSA:1.20.1170.10 25 236 7.4E-4 T 29-03-2018 SMALA_RS17565 e1fa06bf10c1df423f4aaaea7bf79f6d 562 Pfam PF00990 Diguanylate cyclase, GGDEF domain 430 554 6.0E-32 T 29-03-2018 IPR000160 GGDEF domain SMALA_RS17565 e1fa06bf10c1df423f4aaaea7bf79f6d 562 SMART SM00267 325 560 1.4E-27 T 29-03-2018 IPR000160 GGDEF domain SMALA_RS17565 e1fa06bf10c1df423f4aaaea7bf79f6d 562 SUPERFAMILY SSF55073 430 554 9.42E-37 T 29-03-2018 IPR029787 Nucleotide cyclase SMALA_RS17565 e1fa06bf10c1df423f4aaaea7bf79f6d 562 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 209 331 3.6E-15 T 29-03-2018 IPR000014 PAS domain SMALA_RS17565 e1fa06bf10c1df423f4aaaea7bf79f6d 562 SMART SM00086 283 325 3.3E-4 T 29-03-2018 IPR001610 PAC motif SMALA_RS17565 e1fa06bf10c1df423f4aaaea7bf79f6d 562 Gene3D G3DSA:3.30.450.40 6 202 8.0E-22 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS17565 e1fa06bf10c1df423f4aaaea7bf79f6d 562 SMART SM00091 213 283 2.0E-5 T 29-03-2018 IPR000014 PAS domain SMALA_RS17565 e1fa06bf10c1df423f4aaaea7bf79f6d 562 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 430 554 4.7E-30 T 29-03-2018 IPR000160 GGDEF domain SMALA_RS17565 e1fa06bf10c1df423f4aaaea7bf79f6d 562 Gene3D G3DSA:3.30.450.20 203 336 1.7E-29 T 29-03-2018 SMALA_RS17565 e1fa06bf10c1df423f4aaaea7bf79f6d 562 Pfam PF13426 PAS domain 234 322 6.1E-7 T 29-03-2018 IPR000014 PAS domain SMALA_RS17565 e1fa06bf10c1df423f4aaaea7bf79f6d 562 SUPERFAMILY SSF55781 12 191 3.27E-12 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS17565 e1fa06bf10c1df423f4aaaea7bf79f6d 562 Gene3D G3DSA:3.30.70.270 337 561 1.6E-72 T 29-03-2018 SMALA_RS17565 e1fa06bf10c1df423f4aaaea7bf79f6d 562 SUPERFAMILY SSF55785 201 321 1.56E-18 T 29-03-2018 IPR000014 PAS domain SMALA_RS18165 845c7b2bf0b85749abd5d3fcff06fd0d 469 Gene3D G3DSA:3.90.1150.10 332 455 3.7E-31 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS18165 845c7b2bf0b85749abd5d3fcff06fd0d 469 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 50 386 4.4E-73 T 29-03-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 SMALA_RS18165 845c7b2bf0b85749abd5d3fcff06fd0d 469 SUPERFAMILY SSF53383 30 455 8.25E-126 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS18165 845c7b2bf0b85749abd5d3fcff06fd0d 469 Gene3D G3DSA:3.40.640.10 76 331 1.6E-34 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS18165 845c7b2bf0b85749abd5d3fcff06fd0d 469 TIGRFAM TIGR01788 Glu-decarb-GAD: glutamate decarboxylase 37 452 4.5E-186 T 29-03-2018 IPR010107 Glutamate decarboxylase GO:0004351|GO:0006536|GO:0030170 KEGG: 00250+4.1.1.15|KEGG: 00410+4.1.1.15|KEGG: 00430+4.1.1.15|KEGG: 00650+4.1.1.15|MetaCyc: PWY-4321 SMALA_RS22040 6073c37bc53df628ea8c3b886bf40e93 390 Gene3D G3DSA:3.40.50.1820 10 385 6.7E-31 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS22040 6073c37bc53df628ea8c3b886bf40e93 390 SUPERFAMILY SSF53474 283 376 4.4E-24 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS22040 6073c37bc53df628ea8c3b886bf40e93 390 SUPERFAMILY SSF53474 76 225 4.4E-24 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS22040 6073c37bc53df628ea8c3b886bf40e93 390 Pfam PF03583 Secretory lipase 124 385 4.0E-56 T 29-03-2018 IPR005152 Lipase, secreted GO:0004806|GO:0016042 KEGG: 00561+3.1.1.3|MetaCyc: PWY-6857 SMALA_RS22040 6073c37bc53df628ea8c3b886bf40e93 390 PIRSF PIRSF029171 1 388 2.5E-71 T 29-03-2018 IPR005152 Lipase, secreted GO:0004806|GO:0016042 KEGG: 00561+3.1.1.3|MetaCyc: PWY-6857 SMALA_RS16350 ca52eed01691f97d8510c9d94c3a17ad 208 Pfam PF02545 Maf-like protein 7 190 4.0E-47 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 SMALA_RS16350 ca52eed01691f97d8510c9d94c3a17ad 208 PIRSF PIRSF006305 1 197 2.7E-44 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 SMALA_RS16350 ca52eed01691f97d8510c9d94c3a17ad 208 Gene3D G3DSA:3.90.950.10 5 198 1.4E-63 T 29-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like SMALA_RS16350 ca52eed01691f97d8510c9d94c3a17ad 208 SUPERFAMILY SSF52972 5 190 6.54E-53 T 29-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like SMALA_RS16350 ca52eed01691f97d8510c9d94c3a17ad 208 Hamap MF_00528 Septum formation protein Maf [maf]. 6 195 28.26 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 SMALA_RS16350 ca52eed01691f97d8510c9d94c3a17ad 208 TIGRFAM TIGR00172 maf: septum formation protein Maf 5 188 8.9E-48 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 SMALA_RS27795 f77a3a12c792cb6ae003c11e9039b3c7 529 Gene3D G3DSA:3.60.21.10 194 529 1.2E-45 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SMALA_RS27795 f77a3a12c792cb6ae003c11e9039b3c7 529 Gene3D G3DSA:2.60.40.380 83 193 1.2E-16 T 29-03-2018 SMALA_RS27795 f77a3a12c792cb6ae003c11e9039b3c7 529 Pfam PF16656 Purple acid Phosphatase, N-terminal domain 84 189 1.7E-15 T 29-03-2018 IPR015914 Purple acid phosphatase, N-terminal GO:0003993|GO:0046872 SMALA_RS27795 f77a3a12c792cb6ae003c11e9039b3c7 529 SUPERFAMILY SSF56300 195 524 1.19E-45 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SMALA_RS27795 f77a3a12c792cb6ae003c11e9039b3c7 529 Pfam PF00149 Calcineurin-like phosphoesterase 207 406 8.6E-13 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 SMALA_RS27795 f77a3a12c792cb6ae003c11e9039b3c7 529 SUPERFAMILY SSF49363 81 191 1.83E-13 T 29-03-2018 IPR008963 Purple acid phosphatase-like, N-terminal GO:0003993|GO:0046872 SMALA_RS38315 20519ed8e950c1bf9fdd16d39e5d552c 669 Pfam PF07944 Beta-L-arabinofuranosidase, GH127 23 554 3.4E-134 T 29-03-2018 IPR012878 Beta-L-arabinofuranosidase, GH127 KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18 SMALA_RS38315 20519ed8e950c1bf9fdd16d39e5d552c 669 Gene3D G3DSA:1.50.10.10 19 190 2.2E-7 T 29-03-2018 SMALA_RS38315 20519ed8e950c1bf9fdd16d39e5d552c 669 Gene3D G3DSA:1.50.10.10 191 614 3.4E-34 T 29-03-2018 SMALA_RS38315 20519ed8e950c1bf9fdd16d39e5d552c 669 SUPERFAMILY SSF48208 84 421 2.46E-28 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 SMALA_RS23230 7af8712b12ad4265f60010c68490c71d 1003 Gene3D G3DSA:3.40.50.300 2 153 2.4E-6 T 29-03-2018 SMALA_RS23230 7af8712b12ad4265f60010c68490c71d 1003 SUPERFAMILY SSF81901 549 746 1.57E-27 T 29-03-2018 SMALA_RS23230 7af8712b12ad4265f60010c68490c71d 1003 Gene3D G3DSA:1.10.150.200 692 727 4.5E-6 T 29-03-2018 SMALA_RS23230 7af8712b12ad4265f60010c68490c71d 1003 Pfam PF13432 Tetratricopeptide repeat 763 816 1.9E-6 T 29-03-2018 SMALA_RS23230 7af8712b12ad4265f60010c68490c71d 1003 Pfam PF13432 Tetratricopeptide repeat 823 880 5.1E-5 T 29-03-2018 SMALA_RS23230 7af8712b12ad4265f60010c68490c71d 1003 Pfam PF13432 Tetratricopeptide repeat 656 710 9.0E-5 T 29-03-2018 SMALA_RS23230 7af8712b12ad4265f60010c68490c71d 1003 Gene3D G3DSA:1.25.40.10 612 656 3.8E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS23230 7af8712b12ad4265f60010c68490c71d 1003 Gene3D G3DSA:1.25.40.10 846 925 3.4E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS23230 7af8712b12ad4265f60010c68490c71d 1003 SMART SM00028 682 715 2.1E-4 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS23230 7af8712b12ad4265f60010c68490c71d 1003 SMART SM00028 546 579 0.031 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS23230 7af8712b12ad4265f60010c68490c71d 1003 SMART SM00028 782 815 0.011 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS23230 7af8712b12ad4265f60010c68490c71d 1003 SMART SM00028 614 647 0.01 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS23230 7af8712b12ad4265f60010c68490c71d 1003 SMART SM00028 816 849 13.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS23230 7af8712b12ad4265f60010c68490c71d 1003 SMART SM00028 648 681 0.012 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS23230 7af8712b12ad4265f60010c68490c71d 1003 SMART SM00028 580 613 1.9E-5 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS23230 7af8712b12ad4265f60010c68490c71d 1003 SMART SM00028 748 781 0.25 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS23230 7af8712b12ad4265f60010c68490c71d 1003 SMART SM00028 850 883 1.6 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS23230 7af8712b12ad4265f60010c68490c71d 1003 Pfam PF00515 Tetratricopeptide repeat 581 613 1.9E-7 T 29-03-2018 IPR001440 Tetratricopeptide repeat 1 GO:0005515 SMALA_RS23230 7af8712b12ad4265f60010c68490c71d 1003 Gene3D G3DSA:1.10.287.1110 600 611 1.1E-4 T 29-03-2018 SMALA_RS23230 7af8712b12ad4265f60010c68490c71d 1003 Gene3D G3DSA:1.10.287.1110 835 845 0.21 T 29-03-2018 SMALA_RS23230 7af8712b12ad4265f60010c68490c71d 1003 SUPERFAMILY SSF48452 723 885 3.38E-33 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS23230 7af8712b12ad4265f60010c68490c71d 1003 Gene3D G3DSA:1.25.40.10 728 781 2.7E-13 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS23230 7af8712b12ad4265f60010c68490c71d 1003 Gene3D G3DSA:1.25.40.10 657 691 1.6E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS23230 7af8712b12ad4265f60010c68490c71d 1003 Pfam PF13191 AAA ATPase domain 17 135 7.9E-8 T 29-03-2018 SMALA_RS23230 7af8712b12ad4265f60010c68490c71d 1003 Gene3D G3DSA:1.25.40.10 535 599 6.3E-13 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS23230 7af8712b12ad4265f60010c68490c71d 1003 Gene3D G3DSA:1.25.40.10 782 834 1.8E-14 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS38425 e73ae6fb441adcbb5d305ae812e0e4fb 601 Pfam PF00890 FAD binding domain 50 581 4.6E-109 T 29-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMALA_RS38425 e73ae6fb441adcbb5d305ae812e0e4fb 601 Gene3D G3DSA:3.50.50.60 25 601 3.9E-57 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS38425 e73ae6fb441adcbb5d305ae812e0e4fb 601 SUPERFAMILY SSF51905 536 597 6.48E-34 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS38425 e73ae6fb441adcbb5d305ae812e0e4fb 601 SUPERFAMILY SSF51905 42 329 6.48E-34 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS38425 e73ae6fb441adcbb5d305ae812e0e4fb 601 PIRSF PIRSF036654 44 599 1.5E-283 T 29-03-2018 IPR014614 Uncharacterised conserved protein UCP036654 GO:0016627|GO:0055114 SMALA_RS33385 758e8b7fd9cd50113fb269aa1244ba19 342 SUPERFAMILY SSF53659 3 341 3.42E-92 T 29-03-2018 SMALA_RS33385 758e8b7fd9cd50113fb269aa1244ba19 342 SMART SM01329 3 337 4.9E-119 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 SMALA_RS33385 758e8b7fd9cd50113fb269aa1244ba19 342 Gene3D G3DSA:3.40.718.10 1 342 4.3E-93 T 29-03-2018 SMALA_RS33385 758e8b7fd9cd50113fb269aa1244ba19 342 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 4 335 1.0E-75 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 SMALA_RS35910 c1b4fe95c7264766e8e80083c7efe6d0 332 SUPERFAMILY SSF160240 232 304 2.49E-8 T 29-03-2018 SMALA_RS35910 c1b4fe95c7264766e8e80083c7efe6d0 332 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 30 303 7.2E-71 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 SMALA_RS35910 c1b4fe95c7264766e8e80083c7efe6d0 332 Gene3D G3DSA:3.30.70.1350 230 305 3.4E-9 T 29-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain SMALA_RS35910 c1b4fe95c7264766e8e80083c7efe6d0 332 Pfam PF01545 Cation efflux family 33 224 1.6E-41 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 SMALA_RS35910 c1b4fe95c7264766e8e80083c7efe6d0 332 Gene3D G3DSA:1.20.1510.10 29 224 4.3E-47 T 29-03-2018 SMALA_RS35910 c1b4fe95c7264766e8e80083c7efe6d0 332 SUPERFAMILY SSF161111 28 225 7.06E-49 T 29-03-2018 SMALA_RS34630 19aef5fb6cff9da6315693b8fd032833 276 PRINTS PR00111 Alpha/beta hydrolase fold signature 221 235 1.0E-10 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS34630 19aef5fb6cff9da6315693b8fd032833 276 PRINTS PR00111 Alpha/beta hydrolase fold signature 54 69 1.0E-10 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS34630 19aef5fb6cff9da6315693b8fd032833 276 PRINTS PR00111 Alpha/beta hydrolase fold signature 100 113 1.0E-10 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS34630 19aef5fb6cff9da6315693b8fd032833 276 Gene3D G3DSA:3.40.50.1820 21 213 1.2E-19 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS34630 19aef5fb6cff9da6315693b8fd032833 276 Gene3D G3DSA:3.40.50.1820 214 273 5.7E-13 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS34630 19aef5fb6cff9da6315693b8fd032833 276 SUPERFAMILY SSF53474 19 273 6.16E-46 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS34630 19aef5fb6cff9da6315693b8fd032833 276 Pfam PF12697 Alpha/beta hydrolase family 31 269 1.0E-22 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS27330 fb12b3c2718965c544257aa3fe36a72c 287 Gene3D G3DSA:1.10.260.40 4 86 2.0E-15 T 29-03-2018 SMALA_RS27330 fb12b3c2718965c544257aa3fe36a72c 287 Pfam PF13560 Helix-turn-helix domain 6 86 1.3E-15 T 29-03-2018 SMALA_RS27330 fb12b3c2718965c544257aa3fe36a72c 287 SMART SM00530 10 83 8.8E-9 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS27330 fb12b3c2718965c544257aa3fe36a72c 287 SUPERFAMILY SSF47413 31 82 1.6E-8 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS35735 07d09c245420e318b83b5a323f7afef6 235 SUPERFAMILY SSF48613 8 221 6.67E-57 T 29-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 SMALA_RS35735 07d09c245420e318b83b5a323f7afef6 235 Hamap MF_00654 Pyrroloquinoline-quinone synthase [pqqC]. 1 235 95.994 T 29-03-2018 IPR011845 Coenzyme PQQ biosynthesis protein C GO:0018189|GO:0055114 MetaCyc: PWY-6420 SMALA_RS35735 07d09c245420e318b83b5a323f7afef6 235 Gene3D G3DSA:1.20.910.10 1 230 3.3E-33 T 29-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 SMALA_RS35735 07d09c245420e318b83b5a323f7afef6 235 Pfam PF03070 TENA/THI-4/PQQC family 10 220 4.6E-46 T 29-03-2018 IPR004305 Thiaminase-2/PQQC SMALA_RS35735 07d09c245420e318b83b5a323f7afef6 235 TIGRFAM TIGR02111 PQQ_syn_pqqC: coenzyme PQQ biosynthesis protein C 6 228 5.5E-84 T 29-03-2018 IPR011845 Coenzyme PQQ biosynthesis protein C GO:0018189|GO:0055114 MetaCyc: PWY-6420 SMALA_RS39650 133824b932a2ab658958ce8a01585f35 255 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 17 240 1.8E-39 T 29-03-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 SMALA_RS39650 133824b932a2ab658958ce8a01585f35 255 SUPERFAMILY SSF51621 6 252 5.14E-66 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SMALA_RS39650 133824b932a2ab658958ce8a01585f35 255 Gene3D G3DSA:3.20.20.60 2 254 4.9E-39 T 29-03-2018 SMALA_RS10875 018ac6a6295003e981f478d58cf2f091 425 Gene3D G3DSA:3.40.190.10 221 379 4.0E-16 T 29-03-2018 SMALA_RS10875 018ac6a6295003e981f478d58cf2f091 425 Gene3D G3DSA:3.40.190.10 40 220 7.7E-43 T 29-03-2018 SMALA_RS10875 018ac6a6295003e981f478d58cf2f091 425 SUPERFAMILY SSF53850 40 412 2.59E-88 T 29-03-2018 SMALA_RS10875 018ac6a6295003e981f478d58cf2f091 425 Pfam PF13416 Bacterial extracellular solute-binding protein 62 365 2.5E-53 T 29-03-2018 SMALA_RS13990 6e218c300cc83efd215ca5126386881a 389 SUPERFAMILY SSF51569 54 336 1.36E-14 T 29-03-2018 SMALA_RS13990 6e218c300cc83efd215ca5126386881a 389 Pfam PF06187 Protein of unknown function (DUF993) 3 386 9.5E-184 T 29-03-2018 IPR009334 Protein of unknown function DUF993 SMALA_RS13990 6e218c300cc83efd215ca5126386881a 389 Gene3D G3DSA:3.20.20.70 39 358 5.9E-66 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS19250 f515e9cdb822035691873ab5e1bfb1ac 322 Pfam PF02810 SEC-C motif 28 44 5.7E-8 T 29-03-2018 IPR004027 SEC-C motif SMALA_RS19250 f515e9cdb822035691873ab5e1bfb1ac 322 SUPERFAMILY SSF103642 25 44 1.1E-6 T 29-03-2018 SMALA_RS19250 f515e9cdb822035691873ab5e1bfb1ac 322 Gene3D G3DSA:3.10.450.50 2 46 7.5E-8 T 29-03-2018 SMALA_RS33010 0785086228c4580b1d370388cec369fa 148 Pfam PF06103 Bacterial protein of unknown function (DUF948) 6 86 6.5E-14 T 29-03-2018 IPR009293 Uncharacterised protein family UPF0478 SMALA_RS36590 9274ff649ef9cbbf2705cb038dff51af 404 Gene3D G3DSA:3.90.1200.10 57 248 6.6E-5 T 29-03-2018 SMALA_RS36590 9274ff649ef9cbbf2705cb038dff51af 404 Pfam PF06293 Lipopolysaccharide kinase (Kdo/WaaP) family 60 183 6.3E-8 T 29-03-2018 IPR010440 Lipopolysaccharide kinase GO:0005524|GO:0016020|GO:0016773 Reactome: R-HSA-6782315|Reactome: R-HSA-6804756 SMALA_RS36590 9274ff649ef9cbbf2705cb038dff51af 404 SUPERFAMILY SSF56112 35 173 1.87E-6 T 29-03-2018 IPR011009 Protein kinase-like domain SMALA_RS36590 9274ff649ef9cbbf2705cb038dff51af 404 Pfam PF13224 Domain of unknown function (DUF4032) 230 398 5.0E-64 T 29-03-2018 IPR025111 Domain of unknown function DUF4032 SMALA_RS36300 4c4ce692ce3e7f56f9c7f08831ce4238 582 Gene3D G3DSA:2.60.120.260 442 582 4.8E-40 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS36300 4c4ce692ce3e7f56f9c7f08831ce4238 582 SUPERFAMILY SSF51445 40 337 1.96E-43 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS36300 4c4ce692ce3e7f56f9c7f08831ce4238 582 Gene3D G3DSA:2.60.40.10 341 441 1.9E-10 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS36300 4c4ce692ce3e7f56f9c7f08831ce4238 582 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 132 258 1.8E-6 T 29-03-2018 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 SMALA_RS36300 4c4ce692ce3e7f56f9c7f08831ce4238 582 SUPERFAMILY SSF49785 446 581 3.69E-32 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS36300 4c4ce692ce3e7f56f9c7f08831ce4238 582 Pfam PF00754 F5/8 type C domain 461 577 1.1E-28 T 29-03-2018 IPR000421 Coagulation factor 5/8 C-terminal domain SMALA_RS36300 4c4ce692ce3e7f56f9c7f08831ce4238 582 Gene3D G3DSA:3.20.20.80 43 340 7.0E-39 T 29-03-2018 SMALA_RS16635 93c367fd0ba8662425cde8f0e6e4184c 474 ProSitePatterns PS00571 Amidases signature. 151 182 - T 29-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 SMALA_RS16635 93c367fd0ba8662425cde8f0e6e4184c 474 SUPERFAMILY SSF75304 9 466 1.83E-112 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMALA_RS16635 93c367fd0ba8662425cde8f0e6e4184c 474 Pfam PF01425 Amidase 26 446 3.7E-102 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMALA_RS16635 93c367fd0ba8662425cde8f0e6e4184c 474 Gene3D G3DSA:3.90.1300.10 6 473 4.4E-119 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMALA_RS30655 0b73496fe853ec0cb1e19efdd0df355e 428 SUPERFAMILY SSF69118 302 423 6.15E-35 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 SMALA_RS30655 0b73496fe853ec0cb1e19efdd0df355e 428 Gene3D G3DSA:3.40.50.1820 2 256 6.8E-52 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS30655 0b73496fe853ec0cb1e19efdd0df355e 428 Gene3D G3DSA:1.20.1290.10 308 427 7.8E-35 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 SMALA_RS30655 0b73496fe853ec0cb1e19efdd0df355e 428 Pfam PF02627 Carboxymuconolactone decarboxylase family 335 417 1.8E-24 T 29-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SMALA_RS30655 0b73496fe853ec0cb1e19efdd0df355e 428 PRINTS PR00111 Alpha/beta hydrolase fold signature 86 99 3.0E-12 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS30655 0b73496fe853ec0cb1e19efdd0df355e 428 PRINTS PR00111 Alpha/beta hydrolase fold signature 100 113 3.0E-12 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS30655 0b73496fe853ec0cb1e19efdd0df355e 428 PRINTS PR00111 Alpha/beta hydrolase fold signature 43 58 3.0E-12 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS30655 0b73496fe853ec0cb1e19efdd0df355e 428 PRINTS PR00111 Alpha/beta hydrolase fold signature 199 213 3.0E-12 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS30655 0b73496fe853ec0cb1e19efdd0df355e 428 Pfam PF00561 alpha/beta hydrolase fold 18 123 6.5E-18 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS30655 0b73496fe853ec0cb1e19efdd0df355e 428 TIGRFAM TIGR02425 decarb_PcaC: 4-carboxymuconolactone decarboxylase 303 422 3.4E-49 T 29-03-2018 IPR012788 4-carboxymuconolactone decarboxylase KEGG: 00362+4.1.1.44 SMALA_RS30655 0b73496fe853ec0cb1e19efdd0df355e 428 SUPERFAMILY SSF53474 6 253 2.26E-62 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS33930 cbc7b08e35ade156943b312026060416 351 Gene3D G3DSA:3.20.20.70 11 284 1.2E-51 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS33930 cbc7b08e35ade156943b312026060416 351 Pfam PF00682 HMGL-like 16 272 1.1E-62 T 29-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 SMALA_RS33930 cbc7b08e35ade156943b312026060416 351 ProDom PD005364 ALDOLASE 4-HYDROXY-2-OXOVALERATE LYASE PYRUVATE 4.1.3.- PLASMID HMG-COA LYASE-LIKE TRANSFERASE HOA 283 343 6.0E-23 T 29-03-2018 IPR012425 DmpG-like communication GO:0016833|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 SMALA_RS33930 cbc7b08e35ade156943b312026060416 351 TIGRFAM TIGR03217 4OH_2_O_val_ald: 4-hydroxy-2-oxovalerate aldolase 16 345 8.0E-168 T 29-03-2018 IPR017629 4-hydroxy-2-oxovalerate aldolase GO:0008701|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 SMALA_RS33930 cbc7b08e35ade156943b312026060416 351 Hamap MF_01656 4-hydroxy-2-oxovalerate aldolase [mhpE]. 1 351 205.778 T 29-03-2018 IPR017629 4-hydroxy-2-oxovalerate aldolase GO:0008701|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 SMALA_RS33930 cbc7b08e35ade156943b312026060416 351 SUPERFAMILY SSF51569 13 285 2.93E-62 T 29-03-2018 SMALA_RS33930 cbc7b08e35ade156943b312026060416 351 Pfam PF07836 DmpG-like communication domain 284 344 2.1E-31 T 29-03-2018 IPR012425 DmpG-like communication GO:0016833|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 SMALA_RS33930 cbc7b08e35ade156943b312026060416 351 SUPERFAMILY SSF89000 298 346 1.88E-17 T 29-03-2018 SMALA_RS33930 cbc7b08e35ade156943b312026060416 351 Gene3D G3DSA:1.10.8.60 286 347 4.5E-33 T 29-03-2018 SMALA_RS05300 b57eb2351c038b3bbd75b2042d3e928b 1006 Pfam PF09261 Alpha mannosidase middle domain 520 597 1.0E-24 T 29-03-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 SMALA_RS05300 b57eb2351c038b3bbd75b2042d3e928b 1006 Pfam PF07748 Glycosyl hydrolases family 38 C-terminal domain 659 1002 9.8E-51 T 29-03-2018 IPR011682 Glycosyl hydrolase family 38, C-terminal GO:0004559|GO:0006013 SMALA_RS05300 b57eb2351c038b3bbd75b2042d3e928b 1006 SMART SM00872 520 598 2.7E-36 T 29-03-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 SMALA_RS05300 b57eb2351c038b3bbd75b2042d3e928b 1006 Gene3D G3DSA:1.20.1270.50 519 624 4.7E-31 T 29-03-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 SMALA_RS05300 b57eb2351c038b3bbd75b2042d3e928b 1006 Pfam PF01074 Glycosyl hydrolases family 38 N-terminal domain 256 507 1.5E-83 T 29-03-2018 IPR000602 Glycoside hydrolase family 38, N-terminal domain GO:0004559|GO:0006013 SMALA_RS05300 b57eb2351c038b3bbd75b2042d3e928b 1006 SUPERFAMILY SSF88713 253 518 1.56E-75 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 SMALA_RS05300 b57eb2351c038b3bbd75b2042d3e928b 1006 SUPERFAMILY SSF74650 661 1003 1.26E-54 T 29-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 SMALA_RS05300 b57eb2351c038b3bbd75b2042d3e928b 1006 SUPERFAMILY SSF88688 519 625 1.08E-24 T 29-03-2018 IPR028995 Glycoside hydrolase families 57/38, central domain SMALA_RS05300 b57eb2351c038b3bbd75b2042d3e928b 1006 Gene3D G3DSA:3.20.110.10 205 482 4.4E-80 T 29-03-2018 IPR027291 Glycoside hydrolase 38/57, N-terminal domain SMALA_RS06510 03cc3bb47c1646851e026c1bee963d40 200 Gene3D G3DSA:3.40.50.720 2 187 2.6E-27 T 29-03-2018 SMALA_RS06510 03cc3bb47c1646851e026c1bee963d40 200 SUPERFAMILY SSF51735 1 184 2.71E-32 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS06510 03cc3bb47c1646851e026c1bee963d40 200 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 3 91 4.1E-19 T 29-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal SMALA_RS11640 d0631bbbb02f242e0a3afc233ac76590 696 PRINTS PR01036 Tetracycline resistance protein TetB signature 157 181 8.6E-5 T 29-03-2018 SMALA_RS11640 d0631bbbb02f242e0a3afc233ac76590 696 PRINTS PR01036 Tetracycline resistance protein TetB signature 127 147 8.6E-5 T 29-03-2018 SMALA_RS11640 d0631bbbb02f242e0a3afc233ac76590 696 PRINTS PR01036 Tetracycline resistance protein TetB signature 37 61 8.6E-5 T 29-03-2018 SMALA_RS11640 d0631bbbb02f242e0a3afc233ac76590 696 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 33 511 3.1E-85 T 29-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 SMALA_RS11640 d0631bbbb02f242e0a3afc233ac76590 696 Gene3D G3DSA:1.10.10.10 529 673 1.0E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS11640 d0631bbbb02f242e0a3afc233ac76590 696 SUPERFAMILY SSF46785 566 668 7.31E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS11640 d0631bbbb02f242e0a3afc233ac76590 696 Gene3D G3DSA:1.20.1250.20 32 221 2.8E-39 T 29-03-2018 SMALA_RS11640 d0631bbbb02f242e0a3afc233ac76590 696 SUPERFAMILY SSF103473 488 516 6.41E-72 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS11640 d0631bbbb02f242e0a3afc233ac76590 696 SUPERFAMILY SSF103473 268 440 6.41E-72 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS11640 d0631bbbb02f242e0a3afc233ac76590 696 SUPERFAMILY SSF103473 23 214 6.41E-72 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS11640 d0631bbbb02f242e0a3afc233ac76590 696 Gene3D G3DSA:1.20.1250.20 272 521 6.4E-34 T 29-03-2018 SMALA_RS11640 d0631bbbb02f242e0a3afc233ac76590 696 Pfam PF07690 Major Facilitator Superfamily 38 430 6.8E-52 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS18765 133c8f6e30560223a1c1caefff0ce4f0 189 Gene3D G3DSA:1.10.10.10 109 189 3.0E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS18765 133c8f6e30560223a1c1caefff0ce4f0 189 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 28 187 5.0E-57 T 29-03-2018 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 SMALA_RS18765 133c8f6e30560223a1c1caefff0ce4f0 189 Pfam PF04542 Sigma-70 region 2 37 101 2.4E-11 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS18765 133c8f6e30560223a1c1caefff0ce4f0 189 Gene3D G3DSA:1.10.1740.10 17 102 3.2E-14 T 29-03-2018 SMALA_RS18765 133c8f6e30560223a1c1caefff0ce4f0 189 Pfam PF08281 Sigma-70, region 4 128 181 1.7E-12 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS18765 133c8f6e30560223a1c1caefff0ce4f0 189 SUPERFAMILY SSF88659 112 186 5.05E-15 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS18765 133c8f6e30560223a1c1caefff0ce4f0 189 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 33 184 1.9E-22 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS18765 133c8f6e30560223a1c1caefff0ce4f0 189 SUPERFAMILY SSF88946 31 102 9.42E-15 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS04440 f5c47cc7de56fbf17d50bb995366ffcd 227 Pfam PF03713 Domain of unknown function (DUF305) 80 226 3.6E-49 T 29-03-2018 IPR005183 Domain of unknown function DUF305 SMALA_RS04440 f5c47cc7de56fbf17d50bb995366ffcd 227 Gene3D G3DSA:1.20.1260.10 68 227 4.8E-46 T 29-03-2018 IPR012347 Ferritin-related SMALA_RS30465 cb5ff90f83f41d5894e703fcc465a353 383 Pfam PF13478 XdhC Rossmann domain 207 349 1.0E-40 T 29-03-2018 IPR027051 XdhC Rossmann domain SMALA_RS30465 cb5ff90f83f41d5894e703fcc465a353 383 Pfam PF02625 XdhC and CoxI family 119 183 3.9E-12 T 29-03-2018 IPR003777 XdhC- CoxI SMALA_RS30465 cb5ff90f83f41d5894e703fcc465a353 383 Pfam PF02625 XdhC and CoxI family 11 78 8.1E-23 T 29-03-2018 IPR003777 XdhC- CoxI SMALA_RS05195 8bf83d499d533fe4fd7be0284e2f0e2c 337 Pfam PF02653 Branched-chain amino acid transport system / permease component 40 319 1.4E-37 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 SMALA_RS05195 8bf83d499d533fe4fd7be0284e2f0e2c 337 Gene3D G3DSA:1.10.3470.10 5 325 9.6E-26 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SMALA_RS40610 96a17da8d11bce9d7854d7b9dbcdd468 151 Gene3D G3DSA:3.10.129.10 2 151 7.6E-37 T 29-03-2018 SMALA_RS40610 96a17da8d11bce9d7854d7b9dbcdd468 151 SUPERFAMILY SSF54637 9 146 1.08E-33 T 29-03-2018 IPR029069 HotDog domain SMALA_RS40610 96a17da8d11bce9d7854d7b9dbcdd468 151 Pfam PF01575 MaoC like domain 15 123 3.2E-24 T 29-03-2018 IPR002539 MaoC-like domain SMALA_RS33855 700d15479725ca57903b1a174f756c80 344 Pfam PF13407 Periplasmic binding protein domain 45 301 1.8E-53 T 29-03-2018 IPR025997 Periplasmic binding protein SMALA_RS33855 700d15479725ca57903b1a174f756c80 344 SUPERFAMILY SSF53822 40 344 1.45E-64 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SMALA_RS33855 700d15479725ca57903b1a174f756c80 344 Gene3D G3DSA:3.40.50.2300 42 154 1.9E-13 T 29-03-2018 SMALA_RS33855 700d15479725ca57903b1a174f756c80 344 Gene3D G3DSA:3.40.50.2300 155 344 2.9E-19 T 29-03-2018 SMALA_RS33855 700d15479725ca57903b1a174f756c80 344 TIGRFAM TIGR02637 RhaS: rhamnose ABC transporter, rhamnose-binding protein 45 343 3.0E-126 T 29-03-2018 IPR013459 Rhamnose ABC transporter, substrate-binding protein RhaS GO:0015762 SMALA_RS30790 674b43f5f2280e9eeba472ceeb973445 473 SUPERFAMILY SSF51905 438 472 3.69E-27 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS30790 674b43f5f2280e9eeba472ceeb973445 473 SUPERFAMILY SSF51905 6 298 3.69E-27 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS30790 674b43f5f2280e9eeba472ceeb973445 473 Pfam PF13450 NAD(P)-binding Rossmann-like domain 9 56 6.2E-11 T 29-03-2018 SMALA_RS30790 674b43f5f2280e9eeba472ceeb973445 473 Gene3D G3DSA:3.50.50.60 2 472 1.2E-21 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS11770 6afe5240ded516a7120422b05ce057e1 78 Gene3D G3DSA:2.40.50.140 1 77 1.5E-11 T 29-03-2018 SMALA_RS11770 6afe5240ded516a7120422b05ce057e1 78 SUPERFAMILY SSF50249 1 53 3.43E-6 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMALA_RS11770 6afe5240ded516a7120422b05ce057e1 78 Pfam PF00313 'Cold-shock' DNA-binding domain 4 49 2.8E-5 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMALA_RS16090 68779a718596372c86de6b744378857b 213 Gene3D G3DSA:1.10.3720.10 9 212 2.6E-29 T 29-03-2018 SMALA_RS16090 68779a718596372c86de6b744378857b 213 SUPERFAMILY SSF161098 14 195 2.75E-37 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS16090 68779a718596372c86de6b744378857b 213 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 32 197 3.0E-24 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS22430 0cc846f506a0961d211c2aa8dcff3968 144 Pfam PF00298 Ribosomal protein L11, RNA binding domain 74 142 1.9E-26 T 29-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 SMALA_RS22430 0cc846f506a0961d211c2aa8dcff3968 144 Gene3D G3DSA:3.30.1550.10 6 74 2.8E-35 T 29-03-2018 IPR020784 Ribosomal protein L11, N-terminal SMALA_RS22430 0cc846f506a0961d211c2aa8dcff3968 144 SUPERFAMILY SSF46906 70 143 1.31E-27 T 29-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 SMALA_RS22430 0cc846f506a0961d211c2aa8dcff3968 144 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 8 144 31.929 T 29-03-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 SMALA_RS22430 0cc846f506a0961d211c2aa8dcff3968 144 Pfam PF03946 Ribosomal protein L11, N-terminal domain 12 69 1.4E-29 T 29-03-2018 IPR020784 Ribosomal protein L11, N-terminal SMALA_RS22430 0cc846f506a0961d211c2aa8dcff3968 144 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 6 143 5.2E-64 T 29-03-2018 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS22430 0cc846f506a0961d211c2aa8dcff3968 144 ProSitePatterns PS00359 Ribosomal protein L11 signature. 129 144 - T 29-03-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMALA_RS22430 0cc846f506a0961d211c2aa8dcff3968 144 Gene3D G3DSA:1.10.10.250 75 143 4.4E-26 T 29-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 SMALA_RS22430 0cc846f506a0961d211c2aa8dcff3968 144 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 39 76 2.0E-16 T 29-03-2018 SMALA_RS22430 0cc846f506a0961d211c2aa8dcff3968 144 SMART SM00649 12 143 1.6E-88 T 29-03-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 SMALA_RS22430 0cc846f506a0961d211c2aa8dcff3968 144 SUPERFAMILY SSF54747 5 75 3.53E-30 T 29-03-2018 IPR020784 Ribosomal protein L11, N-terminal SMALA_RS19425 a45beb7e6ff5e1a8a14ca838d9d82224 359 SUPERFAMILY SSF53383 27 350 9.32E-77 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS19425 a45beb7e6ff5e1a8a14ca838d9d82224 359 Pfam PF00155 Aminotransferase class I and II 32 346 7.0E-49 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMALA_RS19425 a45beb7e6ff5e1a8a14ca838d9d82224 359 Gene3D G3DSA:3.40.640.10 46 250 6.6E-37 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS19425 a45beb7e6ff5e1a8a14ca838d9d82224 359 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 7 356 49.567 T 29-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 SMALA_RS19425 a45beb7e6ff5e1a8a14ca838d9d82224 359 Hamap MF_01513 Putative phenylalanine aminotransferase [pat]. 8 357 48.593 T 29-03-2018 IPR024892 Putative phenylalanine aminotransferase SMALA_RS19425 a45beb7e6ff5e1a8a14ca838d9d82224 359 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 11 354 2.0E-87 T 29-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 SMALA_RS19425 a45beb7e6ff5e1a8a14ca838d9d82224 359 Gene3D G3DSA:3.90.1150.10 251 356 8.4E-23 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS19425 a45beb7e6ff5e1a8a14ca838d9d82224 359 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 220 229 - T 29-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 SMALA_RS19055 ed04fb1fd4a285150cb300855d94e946 277 Gene3D G3DSA:1.10.10.10 202 277 1.1E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS19055 ed04fb1fd4a285150cb300855d94e946 277 Pfam PF04542 Sigma-70 region 2 57 126 3.0E-18 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS19055 ed04fb1fd4a285150cb300855d94e946 277 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 81 94 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS19055 ed04fb1fd4a285150cb300855d94e946 277 Pfam PF04545 Sigma-70, region 4 222 270 1.4E-15 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS19055 ed04fb1fd4a285150cb300855d94e946 277 Gene3D G3DSA:1.10.10.10 127 179 1.8E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS19055 ed04fb1fd4a285150cb300855d94e946 277 Gene3D G3DSA:1.10.601.10 27 126 1.8E-25 T 29-03-2018 SMALA_RS19055 ed04fb1fd4a285150cb300855d94e946 277 PRINTS PR00046 Major sigma-70 factor signature 81 94 5.5E-8 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS19055 ed04fb1fd4a285150cb300855d94e946 277 PRINTS PR00046 Major sigma-70 factor signature 226 238 5.5E-8 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS19055 ed04fb1fd4a285150cb300855d94e946 277 PRINTS PR00046 Major sigma-70 factor signature 243 258 5.5E-8 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS19055 ed04fb1fd4a285150cb300855d94e946 277 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 54 271 9.5E-33 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS19055 ed04fb1fd4a285150cb300855d94e946 277 SUPERFAMILY SSF88946 31 127 8.9E-31 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS19055 ed04fb1fd4a285150cb300855d94e946 277 SUPERFAMILY SSF88659 130 203 1.05E-12 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS19055 ed04fb1fd4a285150cb300855d94e946 277 SUPERFAMILY SSF88659 208 272 1.07E-14 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS19055 ed04fb1fd4a285150cb300855d94e946 277 Pfam PF04539 Sigma-70 region 3 136 199 4.6E-14 T 29-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS19055 ed04fb1fd4a285150cb300855d94e946 277 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 51 272 4.5E-88 T 29-03-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS35020 58cb58c2d52d0db78c51ed98513592d6 339 Hamap MF_00536 4-hydroxythreonine-4-phosphate dehydrogenase [pdxA]. 9 334 34.37 T 29-03-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 SMALA_RS35020 58cb58c2d52d0db78c51ed98513592d6 339 Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA 40 330 1.4E-100 T 29-03-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 SMALA_RS35020 58cb58c2d52d0db78c51ed98513592d6 339 SUPERFAMILY SSF53659 11 335 9.79E-108 T 29-03-2018 SMALA_RS35020 58cb58c2d52d0db78c51ed98513592d6 339 TIGRFAM TIGR00557 pdxA: 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 13 333 3.5E-107 T 29-03-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 SMALA_RS35020 58cb58c2d52d0db78c51ed98513592d6 339 Gene3D G3DSA:3.40.718.10 1 336 1.0E-125 T 29-03-2018 SMALA_RS01495 3bace2443bd9f102598e7e054d967730 551 Gene3D G3DSA:1.10.10.60 507 526 0.29 T 29-03-2018 SMALA_RS01495 3bace2443bd9f102598e7e054d967730 551 Gene3D G3DSA:1.10.10.10 358 405 1.7E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS01495 3bace2443bd9f102598e7e054d967730 551 Gene3D G3DSA:1.10.260.40 406 470 0.19 T 29-03-2018 SMALA_RS01495 3bace2443bd9f102598e7e054d967730 551 Gene3D G3DSA:1.10.10.60 471 506 0.058 T 29-03-2018 SMALA_RS01495 3bace2443bd9f102598e7e054d967730 551 Pfam PF13556 PucR C-terminal helix-turn-helix domain 486 542 4.5E-10 T 29-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain SMALA_RS01495 3bace2443bd9f102598e7e054d967730 551 Pfam PF13556 PucR C-terminal helix-turn-helix domain 393 435 2.4E-9 T 29-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain SMALA_RS42275 acb011014e1f69efde7ef5186a436e62 256 Gene3D G3DSA:3.40.50.720 8 52 1.8E-8 T 29-03-2018 SMALA_RS42275 acb011014e1f69efde7ef5186a436e62 256 Gene3D G3DSA:3.40.50.720 53 256 1.0E-46 T 29-03-2018 SMALA_RS42275 acb011014e1f69efde7ef5186a436e62 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 3.2E-27 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS42275 acb011014e1f69efde7ef5186a436e62 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 3.2E-27 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS42275 acb011014e1f69efde7ef5186a436e62 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 218 238 3.2E-27 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS42275 acb011014e1f69efde7ef5186a436e62 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 3.2E-27 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS42275 acb011014e1f69efde7ef5186a436e62 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 15 32 3.2E-27 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS42275 acb011014e1f69efde7ef5186a436e62 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 3.2E-27 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS42275 acb011014e1f69efde7ef5186a436e62 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 5.5E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS42275 acb011014e1f69efde7ef5186a436e62 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 5.5E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS42275 acb011014e1f69efde7ef5186a436e62 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 5.5E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS42275 acb011014e1f69efde7ef5186a436e62 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 20 255 5.3E-50 T 29-03-2018 SMALA_RS42275 acb011014e1f69efde7ef5186a436e62 256 SUPERFAMILY SSF51735 13 256 4.48E-62 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS10860 556fa4dd0a8f3250d4991b5cd5fe69ad 347 Gene3D G3DSA:3.40.50.2300 65 179 6.8E-27 T 29-03-2018 SMALA_RS10860 556fa4dd0a8f3250d4991b5cd5fe69ad 347 SUPERFAMILY SSF53822 69 344 1.0E-66 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SMALA_RS10860 556fa4dd0a8f3250d4991b5cd5fe69ad 347 SUPERFAMILY SSF47413 13 59 7.32E-12 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS10860 556fa4dd0a8f3250d4991b5cd5fe69ad 347 ProSitePatterns PS00356 LacI-type HTH domain signature. 15 33 - T 29-03-2018 SMALA_RS10860 556fa4dd0a8f3250d4991b5cd5fe69ad 347 Pfam PF00356 Bacterial regulatory proteins, lacI family 15 57 2.8E-14 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS10860 556fa4dd0a8f3250d4991b5cd5fe69ad 347 Gene3D G3DSA:1.10.260.40 12 64 1.3E-16 T 29-03-2018 SMALA_RS10860 556fa4dd0a8f3250d4991b5cd5fe69ad 347 Gene3D G3DSA:3.40.50.2300 180 346 8.9E-45 T 29-03-2018 SMALA_RS10860 556fa4dd0a8f3250d4991b5cd5fe69ad 347 Pfam PF13377 Periplasmic binding protein-like domain 181 343 1.3E-32 T 29-03-2018 SMALA_RS10860 556fa4dd0a8f3250d4991b5cd5fe69ad 347 SMART SM00354 12 79 3.1E-22 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS33270 162590de698ea4fc81bcf1aaccad7243 294 Gene3D G3DSA:3.20.20.60 4 282 1.0E-47 T 29-03-2018 SMALA_RS33270 162590de698ea4fc81bcf1aaccad7243 294 Pfam PF13714 Phosphoenolpyruvate phosphomutase 17 251 1.5E-63 T 29-03-2018 SMALA_RS33270 162590de698ea4fc81bcf1aaccad7243 294 SUPERFAMILY SSF51621 12 256 8.97E-47 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SMALA_RS33680 0c7bd8937c45a879a03044da73dacef9 420 SUPERFAMILY SSF54556 321 380 6.48E-15 T 29-03-2018 IPR029070 Chitinase insertion domain SMALA_RS33680 0c7bd8937c45a879a03044da73dacef9 420 SUPERFAMILY SSF51445 379 416 4.62E-84 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS33680 0c7bd8937c45a879a03044da73dacef9 420 SUPERFAMILY SSF51445 51 319 4.62E-84 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS33680 0c7bd8937c45a879a03044da73dacef9 420 SMART SM00636 55 409 5.4E-115 T 29-03-2018 IPR011583 Chitinase II GO:0008061 SMALA_RS33680 0c7bd8937c45a879a03044da73dacef9 420 Pfam PF00704 Glycosyl hydrolases family 18 56 409 1.0E-78 T 29-03-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 SMALA_RS33680 0c7bd8937c45a879a03044da73dacef9 420 Gene3D G3DSA:3.20.20.80 10 420 3.7E-91 T 29-03-2018 SMALA_RS33680 0c7bd8937c45a879a03044da73dacef9 420 ProSitePatterns PS01095 Chitinases family 18 active site. 190 198 - T 29-03-2018 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 SMALA_RS15675 36b7c2eeed4022f2f6e391dfac90ac82 625 Pfam PF10647 Lipoprotein LpqB beta-propeller domain 363 624 2.1E-42 T 29-03-2018 IPR018910 Lipoprotein LpqB, beta-propeller domain, C-terminal SMALA_RS15675 36b7c2eeed4022f2f6e391dfac90ac82 625 SUPERFAMILY SSF69322 331 600 1.7E-11 T 29-03-2018 SMALA_RS15675 36b7c2eeed4022f2f6e391dfac90ac82 625 Gene3D G3DSA:2.130.10.150 493 622 8.3E-5 T 29-03-2018 SMALA_RS15675 36b7c2eeed4022f2f6e391dfac90ac82 625 Gene3D G3DSA:2.130.10.10 11 492 6.6E-8 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMALA_RS29080 14b8840f3b20965814e1bf4af313ec51 556 Pfam PF17203 Single cache domain 3 52 184 4.5E-26 T 29-03-2018 IPR033463 Single cache domain 3 SMALA_RS29080 14b8840f3b20965814e1bf4af313ec51 556 Pfam PF00989 PAS fold 231 279 1.2E-6 T 29-03-2018 IPR013767 PAS fold GO:0006355 SMALA_RS29080 14b8840f3b20965814e1bf4af313ec51 556 Gene3D G3DSA:3.30.450.20 213 331 8.2E-11 T 29-03-2018 SMALA_RS29080 14b8840f3b20965814e1bf4af313ec51 556 SUPERFAMILY SSF55890 333 402 1.24E-8 T 29-03-2018 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 SMALA_RS29080 14b8840f3b20965814e1bf4af313ec51 556 SUPERFAMILY SSF55874 396 541 1.18E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS29080 14b8840f3b20965814e1bf4af313ec51 556 PRINTS PR00344 Bacterial sensor protein C-terminal signature 524 537 3.1E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS29080 14b8840f3b20965814e1bf4af313ec51 556 PRINTS PR00344 Bacterial sensor protein C-terminal signature 467 481 3.1E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS29080 14b8840f3b20965814e1bf4af313ec51 556 PRINTS PR00344 Bacterial sensor protein C-terminal signature 500 518 3.1E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS29080 14b8840f3b20965814e1bf4af313ec51 556 SUPERFAMILY SSF55785 233 292 5.23E-6 T 29-03-2018 IPR000014 PAS domain SMALA_RS29080 14b8840f3b20965814e1bf4af313ec51 556 Gene3D G3DSA:3.30.565.10 385 539 3.9E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS29080 14b8840f3b20965814e1bf4af313ec51 556 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 429 538 1.9E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS29080 14b8840f3b20965814e1bf4af313ec51 556 SUPERFAMILY SSF103190 53 183 4.71E-31 T 29-03-2018 IPR029151 Periplasmic sensor domain-like SMALA_RS29080 14b8840f3b20965814e1bf4af313ec51 556 SMART SM00091 230 295 2.6E-4 T 29-03-2018 IPR000014 PAS domain SMALA_RS29080 14b8840f3b20965814e1bf4af313ec51 556 Gene3D G3DSA:3.30.450.20 48 181 9.1E-23 T 29-03-2018 SMALA_RS29080 14b8840f3b20965814e1bf4af313ec51 556 Gene3D G3DSA:1.10.287.130 332 384 1.3E-15 T 29-03-2018 SMALA_RS29080 14b8840f3b20965814e1bf4af313ec51 556 SMART SM00387 428 540 2.0E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS22435 1c66ba93fe97e6088453f62303472c21 239 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 139 - T 29-03-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMALA_RS22435 1c66ba93fe97e6088453f62303472c21 239 Gene3D G3DSA:3.30.190.20 145 224 1.4E-18 T 29-03-2018 SMALA_RS22435 1c66ba93fe97e6088453f62303472c21 239 Pfam PF00687 Ribosomal protein L1p/L10e family 32 220 1.0E-53 T 29-03-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein SMALA_RS22435 1c66ba93fe97e6088453f62303472c21 239 Gene3D G3DSA:3.40.50.790 68 144 2.0E-36 T 29-03-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich SMALA_RS22435 1c66ba93fe97e6088453f62303472c21 239 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 227 4.6E-102 T 29-03-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 SMALA_RS22435 1c66ba93fe97e6088453f62303472c21 239 PIRSF PIRSF002155 1 227 4.5E-74 T 29-03-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMALA_RS22435 1c66ba93fe97e6088453f62303472c21 239 SUPERFAMILY SSF56808 7 226 6.93E-82 T 29-03-2018 IPR023674 Ribosomal protein L1-like SMALA_RS22435 1c66ba93fe97e6088453f62303472c21 239 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 229 42.859 T 29-03-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 SMALA_RS13590 7974091678756850ddf127239ad8e911 136 Gene3D G3DSA:3.10.180.10 3 135 5.5E-18 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS13590 7974091678756850ddf127239ad8e911 136 SUPERFAMILY SSF54593 9 131 1.07E-16 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS13590 7974091678756850ddf127239ad8e911 136 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 12 126 1.2E-5 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMALA_RS00105 d455f1e950a08c1d996141ee11aedfb9 307 Pfam PF01040 UbiA prenyltransferase family 43 283 2.5E-49 T 29-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 SMALA_RS00105 d455f1e950a08c1d996141ee11aedfb9 307 TIGRFAM TIGR01475 ubiA_other: putative 4-hydroxybenzoate polyprenyltransferase 20 301 3.4E-86 T 29-03-2018 IPR006371 4-hydroxybenzoate polyprenyltransferase-related SMALA_RS21985 d455f1e950a08c1d996141ee11aedfb9 307 Pfam PF01040 UbiA prenyltransferase family 43 283 2.5E-49 T 29-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 SMALA_RS21985 d455f1e950a08c1d996141ee11aedfb9 307 TIGRFAM TIGR01475 ubiA_other: putative 4-hydroxybenzoate polyprenyltransferase 20 301 3.4E-86 T 29-03-2018 IPR006371 4-hydroxybenzoate polyprenyltransferase-related SMALA_RS24955 5895bcbbbc3cc1377bb876a922a4a5bd 106 PIRSF PIRSF006488 22 105 7.3E-24 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 SMALA_RS24955 5895bcbbbc3cc1377bb876a922a4a5bd 106 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 32 72 2.0E-14 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 SMALA_RS24955 5895bcbbbc3cc1377bb876a922a4a5bd 106 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 33 93 13.828 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 SMALA_RS24955 5895bcbbbc3cc1377bb876a922a4a5bd 106 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 34 88 1.9E-20 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 SMALA_RS24955 5895bcbbbc3cc1377bb876a922a4a5bd 106 SUPERFAMILY SSF116842 30 91 3.27E-16 T 29-03-2018 SMALA_RS24955 5895bcbbbc3cc1377bb876a922a4a5bd 106 Pfam PF02609 Exonuclease VII small subunit 34 83 9.3E-18 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 SMALA_RS24955 5895bcbbbc3cc1377bb876a922a4a5bd 106 Gene3D G3DSA:1.10.287.1040 31 98 6.9E-21 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 SMALA_RS30670 ea401a9210a319554732a7502ac310b4 602 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 396 589 2.4E-17 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain SMALA_RS30670 ea401a9210a319554732a7502ac310b4 602 SUPERFAMILY SSF52266 391 595 2.17E-39 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain SMALA_RS30670 ea401a9210a319554732a7502ac310b4 602 Gene3D G3DSA:3.40.50.1110 388 596 7.6E-22 T 29-03-2018 SMALA_RS21295 f4cfd9b6eca4420211855998c80ae750 82 Pfam PF04149 Domain of unknown function (DUF397) 21 63 1.6E-7 T 29-03-2018 IPR007278 Domain of unknown function DUF397 SMALA_RS18230 ad34340b2b0e8a71576b1984be22039b 198 Pfam PF04542 Sigma-70 region 2 40 108 7.4E-16 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS18230 ad34340b2b0e8a71576b1984be22039b 198 SUPERFAMILY SSF88659 124 192 8.29E-13 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS18230 ad34340b2b0e8a71576b1984be22039b 198 Gene3D G3DSA:1.10.1740.10 24 105 5.8E-21 T 29-03-2018 SMALA_RS18230 ad34340b2b0e8a71576b1984be22039b 198 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 63 95 - T 29-03-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS18230 ad34340b2b0e8a71576b1984be22039b 198 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 37 190 2.8E-23 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS18230 ad34340b2b0e8a71576b1984be22039b 198 SUPERFAMILY SSF88946 32 124 2.59E-20 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS18230 ad34340b2b0e8a71576b1984be22039b 198 Gene3D G3DSA:1.10.10.10 106 198 1.3E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS18230 ad34340b2b0e8a71576b1984be22039b 198 Pfam PF04545 Sigma-70, region 4 140 188 5.5E-13 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS10370 2ff92059a4e4831e1204c3f740054d52 291 SMART SM00518 9 287 1.3E-98 T 29-03-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 SMALA_RS10370 2ff92059a4e4831e1204c3f740054d52 291 ProSitePatterns PS00730 AP endonucleases family 2 signature 2. 182 189 - T 29-03-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 SMALA_RS10370 2ff92059a4e4831e1204c3f740054d52 291 TIGRFAM TIGR00587 nfo: apurinic endonuclease (APN1) 10 284 1.3E-61 T 29-03-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 SMALA_RS10370 2ff92059a4e4831e1204c3f740054d52 291 Pfam PF01261 Xylose isomerase-like TIM barrel 26 246 1.8E-30 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SMALA_RS10370 2ff92059a4e4831e1204c3f740054d52 291 SUPERFAMILY SSF51658 10 286 5.37E-71 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SMALA_RS10370 2ff92059a4e4831e1204c3f740054d52 291 ProSitePatterns PS00731 AP endonucleases family 2 signature 3. 222 238 - T 29-03-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 SMALA_RS10370 2ff92059a4e4831e1204c3f740054d52 291 Gene3D G3DSA:3.20.20.150 7 291 1.4E-50 T 29-03-2018 SMALA_RS10370 2ff92059a4e4831e1204c3f740054d52 291 Hamap MF_00152 Probable endonuclease 4 [nfo]. 8 287 38.361 T 29-03-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 SMALA_RS10370 2ff92059a4e4831e1204c3f740054d52 291 ProSitePatterns PS00729 AP endonucleases family 2 signature 1. 73 81 - T 29-03-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 SMALA_RS03575 bd83a2fe6a01c20599ebab78aef4f1cd 259 Pfam PF03746 LamB/YcsF family 10 248 6.5E-100 T 29-03-2018 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF SMALA_RS03575 bd83a2fe6a01c20599ebab78aef4f1cd 259 Gene3D G3DSA:3.20.20.370 9 257 3.1E-106 T 29-03-2018 SMALA_RS03575 bd83a2fe6a01c20599ebab78aef4f1cd 259 Hamap MF_00691 UPF0271 protein YbgL [ybgL]. 8 253 43.695 T 29-03-2018 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF SMALA_RS03575 bd83a2fe6a01c20599ebab78aef4f1cd 259 SUPERFAMILY SSF88713 9 258 2.45E-93 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 SMALA_RS12130 b0839d69775ab2bb5cdeaf544fd0b35e 266 Pfam PF07264 Etoposide-induced protein 2.4 (EI24) 10 229 7.9E-31 T 29-03-2018 SMALA_RS30495 eb5c6369f4bd17c74d2377fd84d05722 574 Pfam PF00501 AMP-binding enzyme 37 448 7.9E-111 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS30495 eb5c6369f4bd17c74d2377fd84d05722 574 ProSitePatterns PS00455 Putative AMP-binding domain signature. 197 208 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS30495 eb5c6369f4bd17c74d2377fd84d05722 574 Gene3D G3DSA:2.30.38.10 357 440 3.1E-28 T 29-03-2018 SMALA_RS30495 eb5c6369f4bd17c74d2377fd84d05722 574 SUPERFAMILY SSF56801 28 545 6.54E-160 T 29-03-2018 SMALA_RS30495 eb5c6369f4bd17c74d2377fd84d05722 574 Gene3D G3DSA:3.30.300.30 441 544 2.8E-30 T 29-03-2018 SMALA_RS30495 eb5c6369f4bd17c74d2377fd84d05722 574 Gene3D G3DSA:3.40.50.980 27 202 4.3E-40 T 29-03-2018 SMALA_RS30495 eb5c6369f4bd17c74d2377fd84d05722 574 Pfam PF13193 AMP-binding enzyme C-terminal domain 457 533 1.5E-18 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS30495 eb5c6369f4bd17c74d2377fd84d05722 574 Gene3D G3DSA:3.40.50.980 203 356 1.9E-51 T 29-03-2018 SMALA_RS13335 f4ca3c243c8b6c487d71a44b8ce48da3 475 PIRSF PIRSF006060 9 470 1.1E-60 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMALA_RS13335 f4ca3c243c8b6c487d71a44b8ce48da3 475 ProSitePatterns PS00218 Amino acid permeases signature. 60 90 - T 29-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 SMALA_RS13335 f4ca3c243c8b6c487d71a44b8ce48da3 475 Pfam PF00324 Amino acid permease 35 445 8.9E-100 T 29-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 SMALA_RS17755 958c85447e39223c0a930a0c926c1e12 134 SUPERFAMILY SSF55874 32 124 1.14E-9 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS17755 958c85447e39223c0a930a0c926c1e12 134 Gene3D G3DSA:3.30.565.10 3 134 1.2E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS17755 958c85447e39223c0a930a0c926c1e12 134 Pfam PF13581 Histidine kinase-like ATPase domain 15 122 1.7E-13 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS35570 3d9bd8af84221a86d36e472954a3cf7c 304 Pfam PF04264 YceI-like domain 125 292 4.8E-36 T 29-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like SMALA_RS35570 3d9bd8af84221a86d36e472954a3cf7c 304 Pfam PF13620 Carboxypeptidase regulatory-like domain 34 102 1.0E-8 T 29-03-2018 SMALA_RS35570 3d9bd8af84221a86d36e472954a3cf7c 304 Gene3D G3DSA:2.60.40.1120 32 118 4.2E-10 T 29-03-2018 SMALA_RS35570 3d9bd8af84221a86d36e472954a3cf7c 304 SMART SM00867 124 293 4.7E-48 T 29-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like SMALA_RS35570 3d9bd8af84221a86d36e472954a3cf7c 304 SUPERFAMILY SSF49464 35 103 8.24E-9 T 29-03-2018 IPR008969 Carboxypeptidase-like, regulatory domain SMALA_RS35570 3d9bd8af84221a86d36e472954a3cf7c 304 SUPERFAMILY SSF101874 123 293 3.27E-44 T 29-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like SMALA_RS35570 3d9bd8af84221a86d36e472954a3cf7c 304 Gene3D G3DSA:2.40.128.110 121 301 1.7E-45 T 29-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like SMALA_RS27750 7cc9de5bfbb892021c475966e5a1c6b1 204 PRINTS PR00400 Tetracycline repressor protein signature 133 152 5.0E-6 T 29-03-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 SMALA_RS27750 7cc9de5bfbb892021c475966e5a1c6b1 204 PRINTS PR00400 Tetracycline repressor protein signature 188 202 5.0E-6 T 29-03-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 SMALA_RS27750 7cc9de5bfbb892021c475966e5a1c6b1 204 PRINTS PR00400 Tetracycline repressor protein signature 24 47 5.0E-6 T 29-03-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 SMALA_RS27750 7cc9de5bfbb892021c475966e5a1c6b1 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 54 2.5E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS27750 7cc9de5bfbb892021c475966e5a1c6b1 204 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 71 203 2.0E-16 T 29-03-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 SMALA_RS27750 7cc9de5bfbb892021c475966e5a1c6b1 204 SUPERFAMILY SSF48498 70 203 8.15E-25 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS27750 7cc9de5bfbb892021c475966e5a1c6b1 204 Gene3D G3DSA:1.10.357.10 67 204 1.4E-26 T 29-03-2018 SMALA_RS27750 7cc9de5bfbb892021c475966e5a1c6b1 204 Gene3D G3DSA:1.10.10.60 2 33 2.2E-12 T 29-03-2018 SMALA_RS27750 7cc9de5bfbb892021c475966e5a1c6b1 204 SUPERFAMILY SSF46689 1 65 1.15E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS27750 7cc9de5bfbb892021c475966e5a1c6b1 204 Gene3D G3DSA:1.10.260.40 34 66 4.0E-9 T 29-03-2018 SMALA_RS02185 772d3635b47f53d954752dec770084e5 1242 Gene3D G3DSA:1.25.10.10 430 787 2.6E-4 T 29-03-2018 IPR011989 Armadillo-like helical SMALA_RS02185 772d3635b47f53d954752dec770084e5 1242 Pfam PF12770 CHAT domain 901 1229 2.3E-34 T 29-03-2018 IPR024983 CHAT domain SMALA_RS02185 772d3635b47f53d954752dec770084e5 1242 Gene3D G3DSA:3.40.50.1460 963 1234 7.7E-15 T 29-03-2018 SMALA_RS09255 963f43e8b15657b05569871fc6b9e70e 295 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 43 259 1.9E-39 T 29-03-2018 IPR008775 Phytanoyl-CoA dioxygenase SMALA_RS09255 963f43e8b15657b05569871fc6b9e70e 295 TIGRFAM TIGR02408 ectoine_ThpD: ectoine hydroxylase 19 295 4.7E-148 T 29-03-2018 IPR012774 Ectoine dioxygenase GO:0016706|GO:0055114 SMALA_RS09255 963f43e8b15657b05569871fc6b9e70e 295 Gene3D G3DSA:2.60.120.620 26 279 6.5E-45 T 29-03-2018 SMALA_RS09255 963f43e8b15657b05569871fc6b9e70e 295 SUPERFAMILY SSF51197 31 293 2.66E-61 T 29-03-2018 SMALA_RS03825 6bb5f19be20cabb960110c609b4695cb 341 Pfam PF04932 O-Antigen ligase 134 271 2.3E-6 T 29-03-2018 IPR007016 O-antigen ligase-related SMALA_RS42065 5908e1bd66d4f0958f7d4ed02a973ef7 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 89 100 5.2E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS42065 5908e1bd66d4f0958f7d4ed02a973ef7 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 163 182 5.2E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS42065 5908e1bd66d4f0958f7d4ed02a973ef7 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 143 151 5.2E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS42065 5908e1bd66d4f0958f7d4ed02a973ef7 259 SUPERFAMILY SSF51735 17 258 3.97E-73 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS42065 5908e1bd66d4f0958f7d4ed02a973ef7 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 17 34 2.7E-32 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS42065 5908e1bd66d4f0958f7d4ed02a973ef7 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 137 153 2.7E-32 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS42065 5908e1bd66d4f0958f7d4ed02a973ef7 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 183 200 2.7E-32 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS42065 5908e1bd66d4f0958f7d4ed02a973ef7 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 89 100 2.7E-32 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS42065 5908e1bd66d4f0958f7d4ed02a973ef7 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 220 240 2.7E-32 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS42065 5908e1bd66d4f0958f7d4ed02a973ef7 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 182 2.7E-32 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS42065 5908e1bd66d4f0958f7d4ed02a973ef7 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 24 255 1.2E-51 T 29-03-2018 SMALA_RS42065 5908e1bd66d4f0958f7d4ed02a973ef7 259 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 150 178 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMALA_RS42065 5908e1bd66d4f0958f7d4ed02a973ef7 259 Gene3D G3DSA:3.40.50.720 7 259 2.6E-68 T 29-03-2018 SMALA_RS42065 5908e1bd66d4f0958f7d4ed02a973ef7 259 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 16 188 0.0067 T 29-03-2018 SMALA_RS30700 0e86c87d1af5e23feb907b3a6d4a9bcb 556 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 81 361 3.5E-19 T 29-03-2018 IPR005674 CocE/Serine esterase GO:0016787 SMALA_RS30700 0e86c87d1af5e23feb907b3a6d4a9bcb 556 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 349 545 2.4E-17 T 29-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 SMALA_RS30700 0e86c87d1af5e23feb907b3a6d4a9bcb 556 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 80 318 2.8E-34 T 29-03-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 SMALA_RS30700 0e86c87d1af5e23feb907b3a6d4a9bcb 556 SUPERFAMILY SSF53474 24 357 1.07E-48 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS30700 0e86c87d1af5e23feb907b3a6d4a9bcb 556 Gene3D G3DSA:2.60.120.260 344 556 1.7E-31 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS30700 0e86c87d1af5e23feb907b3a6d4a9bcb 556 Gene3D G3DSA:3.40.50.1820 31 343 2.3E-39 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS30700 0e86c87d1af5e23feb907b3a6d4a9bcb 556 SUPERFAMILY SSF49785 427 555 1.06E-16 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS30700 0e86c87d1af5e23feb907b3a6d4a9bcb 556 SMART SM00939 337 550 1.2E-22 T 29-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 SMALA_RS22060 63a32c27542106933aae5502f45e278f 272 Gene3D G3DSA:3.40.190.10 128 258 4.7E-30 T 29-03-2018 SMALA_RS22060 63a32c27542106933aae5502f45e278f 272 Gene3D G3DSA:3.40.190.10 1 122 4.5E-18 T 29-03-2018 SMALA_RS22060 63a32c27542106933aae5502f45e278f 272 Hamap MF_00995 Chorismate dehydratase [mqnA]. 1 262 29.48 T 29-03-2018 IPR030868 Chorismate dehydratase GO:0009234|GO:0016829 KEGG: 00130+4.2.1.151|MetaCyc: PWY-7371|MetaCyc: PWY-7374 SMALA_RS22060 63a32c27542106933aae5502f45e278f 272 Pfam PF02621 Menaquinone biosynthesis 1 256 1.0E-71 T 29-03-2018 IPR003773 Menaquinone biosynthesis enzyme SMALA_RS22060 63a32c27542106933aae5502f45e278f 272 SUPERFAMILY SSF53850 1 255 6.3E-77 T 29-03-2018 SMALA_RS31755 05d580263a1088f017009c71de55a9b7 132 PIRSF PIRSF028743 9 131 2.1E-32 T 29-03-2018 IPR008634 Gas vesicle protein GvpO GO:0031412 SMALA_RS31755 05d580263a1088f017009c71de55a9b7 132 Pfam PF05800 Gas vesicle synthesis protein GvpO 40 129 1.1E-29 T 29-03-2018 IPR008634 Gas vesicle protein GvpO GO:0031412 SMALA_RS09910 889c4e02bd52f38964cddfe245f72446 499 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 90 243 2.4E-12 T 29-03-2018 SMALA_RS42005 9d4795cdf5cf35358e94072f03881c57 345 Gene3D G3DSA:3.40.50.720 148 303 1.2E-15 T 29-03-2018 SMALA_RS42005 9d4795cdf5cf35358e94072f03881c57 345 PIRSF PIRSF001439 16 331 1.1E-46 T 29-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 SMALA_RS42005 9d4795cdf5cf35358e94072f03881c57 345 Gene3D G3DSA:3.30.1780.10 1 147 1.5E-34 T 29-03-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 SMALA_RS42005 9d4795cdf5cf35358e94072f03881c57 345 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 18 309 2.8E-49 T 29-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 SMALA_RS42005 9d4795cdf5cf35358e94072f03881c57 345 SUPERFAMILY SSF51735 3 334 9.43E-68 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS41110 0fe4816b867bae6d08c5ab1e1f9cb1db 153 ProSitePatterns PS00519 AsnC-type HTH domain signature. 19 45 - T 29-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site SMALA_RS41110 0fe4816b867bae6d08c5ab1e1f9cb1db 153 Gene3D G3DSA:1.10.10.10 2 53 2.7E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS41110 0fe4816b867bae6d08c5ab1e1f9cb1db 153 SUPERFAMILY SSF54909 63 150 5.09E-19 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel SMALA_RS41110 0fe4816b867bae6d08c5ab1e1f9cb1db 153 Pfam PF13412 Winged helix-turn-helix DNA-binding 1 48 1.0E-17 T 29-03-2018 SMALA_RS41110 0fe4816b867bae6d08c5ab1e1f9cb1db 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 7.8E-17 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMALA_RS41110 0fe4816b867bae6d08c5ab1e1f9cb1db 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 7.8E-17 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMALA_RS41110 0fe4816b867bae6d08c5ab1e1f9cb1db 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 7.8E-17 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMALA_RS41110 0fe4816b867bae6d08c5ab1e1f9cb1db 153 SUPERFAMILY SSF46785 1 60 3.11E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS41110 0fe4816b867bae6d08c5ab1e1f9cb1db 153 Pfam PF01037 Lrp/AsnC ligand binding domain 67 141 1.9E-18 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain SMALA_RS41110 0fe4816b867bae6d08c5ab1e1f9cb1db 153 Gene3D G3DSA:3.30.70.920 54 147 3.2E-23 T 29-03-2018 SMALA_RS41110 0fe4816b867bae6d08c5ab1e1f9cb1db 153 SMART SM00344 1 110 6.2E-39 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 SMALA_RS36020 d316a1804902adba2ba70999172bc173 321 Gene3D G3DSA:3.90.25.10 176 315 1.4E-21 T 29-03-2018 SMALA_RS36020 d316a1804902adba2ba70999172bc173 321 Pfam PF01370 NAD dependent epimerase/dehydratase family 10 235 4.8E-36 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 SMALA_RS36020 d316a1804902adba2ba70999172bc173 321 Gene3D G3DSA:3.40.50.720 8 175 5.7E-25 T 29-03-2018 SMALA_RS36020 d316a1804902adba2ba70999172bc173 321 SUPERFAMILY SSF51735 3 303 9.83E-57 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS14645 02e6e8718f5e03fc4fd0e9ee5e842dd6 272 Gene3D G3DSA:3.90.470.20 155 236 1.2E-7 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 SMALA_RS14645 02e6e8718f5e03fc4fd0e9ee5e842dd6 272 SUPERFAMILY SSF56214 39 137 3.45E-17 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 SMALA_RS14645 02e6e8718f5e03fc4fd0e9ee5e842dd6 272 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 144 208 3.1E-9 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 SMALA_RS14645 02e6e8718f5e03fc4fd0e9ee5e842dd6 272 Gene3D G3DSA:3.90.470.20 34 154 6.8E-22 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 SMALA_RS14645 02e6e8718f5e03fc4fd0e9ee5e842dd6 272 SUPERFAMILY SSF56214 144 253 1.11E-18 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 SMALA_RS26210 e0755c193d0878005e95887bda004eca 214 Gene3D G3DSA:3.90.45.10 17 210 1.0E-58 T 29-03-2018 IPR023635 Peptide deformylase SMALA_RS26210 e0755c193d0878005e95887bda004eca 214 SUPERFAMILY SSF56420 33 196 2.88E-53 T 29-03-2018 IPR023635 Peptide deformylase SMALA_RS26210 e0755c193d0878005e95887bda004eca 214 Hamap MF_00163 Peptide deformylase [def]. 33 199 27.605 T 29-03-2018 IPR023635 Peptide deformylase SMALA_RS26210 e0755c193d0878005e95887bda004eca 214 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 37 196 7.0E-39 T 29-03-2018 IPR023635 Peptide deformylase SMALA_RS26210 e0755c193d0878005e95887bda004eca 214 PIRSF PIRSF004749 2 213 4.7E-44 T 29-03-2018 IPR023635 Peptide deformylase SMALA_RS26210 e0755c193d0878005e95887bda004eca 214 PRINTS PR01576 Peptide deformylase signature 64 93 2.7E-32 T 29-03-2018 IPR023635 Peptide deformylase SMALA_RS26210 e0755c193d0878005e95887bda004eca 214 PRINTS PR01576 Peptide deformylase signature 157 186 2.7E-32 T 29-03-2018 IPR023635 Peptide deformylase SMALA_RS26210 e0755c193d0878005e95887bda004eca 214 PRINTS PR01576 Peptide deformylase signature 126 137 2.7E-32 T 29-03-2018 IPR023635 Peptide deformylase SMALA_RS26210 e0755c193d0878005e95887bda004eca 214 PRINTS PR01576 Peptide deformylase signature 138 156 2.7E-32 T 29-03-2018 IPR023635 Peptide deformylase SMALA_RS26210 e0755c193d0878005e95887bda004eca 214 Pfam PF01327 Polypeptide deformylase 35 189 1.0E-42 T 29-03-2018 IPR023635 Peptide deformylase SMALA_RS12435 a91edb7778e07398b8055ddf3f0adf3a 147 SMART SM00960 12 112 5.2E-16 T 29-03-2018 IPR004942 Roadblock/LAMTOR2 domain SMALA_RS12435 a91edb7778e07398b8055ddf3f0adf3a 147 Gene3D G3DSA:3.30.450.30 7 144 4.7E-31 T 29-03-2018 SMALA_RS12435 a91edb7778e07398b8055ddf3f0adf3a 147 SUPERFAMILY SSF103196 7 141 3.66E-23 T 29-03-2018 SMALA_RS12435 a91edb7778e07398b8055ddf3f0adf3a 147 Pfam PF03259 Roadblock/LC7 domain 15 111 6.1E-16 T 29-03-2018 IPR004942 Roadblock/LAMTOR2 domain SMALA_RS11605 31d8adc09d4547b40ed73fdd81603418 414 Gene3D G3DSA:1.10.630.10 16 414 4.6E-66 T 29-03-2018 SMALA_RS11605 31d8adc09d4547b40ed73fdd81603418 414 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 354 363 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMALA_RS11605 31d8adc09d4547b40ed73fdd81603418 414 SUPERFAMILY SSF48264 25 413 8.64E-91 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS11605 31d8adc09d4547b40ed73fdd81603418 414 PRINTS PR00359 B-class P450 signature 203 225 2.6E-57 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS11605 31d8adc09d4547b40ed73fdd81603418 414 PRINTS PR00359 B-class P450 signature 285 296 2.6E-57 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS11605 31d8adc09d4547b40ed73fdd81603418 414 PRINTS PR00359 B-class P450 signature 303 330 2.6E-57 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS11605 31d8adc09d4547b40ed73fdd81603418 414 PRINTS PR00359 B-class P450 signature 331 346 2.6E-57 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS11605 31d8adc09d4547b40ed73fdd81603418 414 PRINTS PR00359 B-class P450 signature 352 361 2.6E-57 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS11605 31d8adc09d4547b40ed73fdd81603418 414 PRINTS PR00359 B-class P450 signature 102 113 2.6E-57 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS11605 31d8adc09d4547b40ed73fdd81603418 414 PRINTS PR00359 B-class P450 signature 149 165 2.6E-57 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS11605 31d8adc09d4547b40ed73fdd81603418 414 PRINTS PR00359 B-class P450 signature 166 181 2.6E-57 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS11605 31d8adc09d4547b40ed73fdd81603418 414 PRINTS PR00359 B-class P450 signature 361 372 2.6E-57 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS11605 31d8adc09d4547b40ed73fdd81603418 414 Pfam PF00067 Cytochrome P450 286 379 7.0E-18 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS11605 31d8adc09d4547b40ed73fdd81603418 414 PRINTS PR00385 P450 superfamily signature 361 372 3.5E-7 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS11605 31d8adc09d4547b40ed73fdd81603418 414 PRINTS PR00385 P450 superfamily signature 352 361 3.5E-7 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS11605 31d8adc09d4547b40ed73fdd81603418 414 PRINTS PR00385 P450 superfamily signature 285 296 3.5E-7 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS11605 31d8adc09d4547b40ed73fdd81603418 414 PRINTS PR00385 P450 superfamily signature 248 265 3.5E-7 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS23180 be1b9038c4ff9e1d20c40d9543ebc506 409 Gene3D G3DSA:3.20.20.140 2 400 8.3E-63 T 29-03-2018 SMALA_RS23180 be1b9038c4ff9e1d20c40d9543ebc506 409 Pfam PF04909 Amidohydrolase 99 397 3.8E-39 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 SMALA_RS23180 be1b9038c4ff9e1d20c40d9543ebc506 409 SUPERFAMILY SSF51556 6 34 9.83E-69 T 29-03-2018 IPR032466 Metal-dependent hydrolase SMALA_RS23180 be1b9038c4ff9e1d20c40d9543ebc506 409 SUPERFAMILY SSF51556 98 397 9.83E-69 T 29-03-2018 IPR032466 Metal-dependent hydrolase SMALA_RS13680 6e40c6909339f7fe0abea30505223c5d 199 ProSitePatterns PS01081 TetR-type HTH domain signature. 24 54 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site SMALA_RS13680 6e40c6909339f7fe0abea30505223c5d 199 Pfam PF16925 Bacterial transcriptional repressor C-terminal 84 186 2.3E-6 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS13680 6e40c6909339f7fe0abea30505223c5d 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 58 7.4E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS13680 6e40c6909339f7fe0abea30505223c5d 199 SUPERFAMILY SSF48498 79 190 6.09E-25 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS13680 6e40c6909339f7fe0abea30505223c5d 199 SUPERFAMILY SSF46689 2 83 4.72E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS13680 6e40c6909339f7fe0abea30505223c5d 199 Gene3D G3DSA:1.10.357.10 59 193 2.4E-24 T 29-03-2018 SMALA_RS13680 6e40c6909339f7fe0abea30505223c5d 199 Gene3D G3DSA:1.10.10.60 1 58 2.3E-13 T 29-03-2018 SMALA_RS01165 d79185cc1439b00326714a67dae6d055 335 Pfam PF13469 Sulfotransferase family 5 285 5.9E-16 T 29-03-2018 SMALA_RS01165 d79185cc1439b00326714a67dae6d055 335 Gene3D G3DSA:3.40.50.300 3 314 4.6E-29 T 29-03-2018 SMALA_RS01165 d79185cc1439b00326714a67dae6d055 335 SUPERFAMILY SSF52540 145 294 1.4E-23 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS01165 d79185cc1439b00326714a67dae6d055 335 SUPERFAMILY SSF52540 2 39 1.4E-23 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS04670 0521ed34817e4a5c166985bcdfce62c3 232 Gene3D G3DSA:3.40.50.1000 63 231 8.2E-26 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS04670 0521ed34817e4a5c166985bcdfce62c3 232 Pfam PF13419 Haloacid dehalogenase-like hydrolase 50 194 9.9E-11 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS04670 0521ed34817e4a5c166985bcdfce62c3 232 SUPERFAMILY SSF56784 4 229 1.08E-36 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS32885 fbfde295d0179d02d892474ef6c8ea6e 386 Pfam PF13692 Glycosyl transferases group 1 188 328 2.0E-29 T 29-03-2018 SMALA_RS32885 fbfde295d0179d02d892474ef6c8ea6e 386 Gene3D G3DSA:3.40.50.2000 1 173 2.2E-18 T 29-03-2018 SMALA_RS32885 fbfde295d0179d02d892474ef6c8ea6e 386 Gene3D G3DSA:3.40.50.2000 174 358 2.5E-39 T 29-03-2018 SMALA_RS32885 fbfde295d0179d02d892474ef6c8ea6e 386 Pfam PF13439 Glycosyltransferase Family 4 14 172 2.0E-33 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 SMALA_RS32885 fbfde295d0179d02d892474ef6c8ea6e 386 SUPERFAMILY SSF53756 3 363 5.23E-82 T 29-03-2018 SMALA_RS33700 d071291ca707dabcd1c69139fa0962b2 548 Pfam PF07969 Amidohydrolase family 58 543 5.1E-98 T 29-03-2018 IPR013108 Amidohydrolase 3 SMALA_RS33700 d071291ca707dabcd1c69139fa0962b2 548 Gene3D G3DSA:2.30.40.10 1 126 1.2E-17 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS33700 d071291ca707dabcd1c69139fa0962b2 548 SUPERFAMILY SSF51338 8 70 1.09E-11 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS33700 d071291ca707dabcd1c69139fa0962b2 548 SUPERFAMILY SSF51338 479 518 1.09E-11 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS33700 d071291ca707dabcd1c69139fa0962b2 548 SUPERFAMILY SSF51556 197 477 1.67E-37 T 29-03-2018 IPR032466 Metal-dependent hydrolase SMALA_RS33700 d071291ca707dabcd1c69139fa0962b2 548 SUPERFAMILY SSF51556 69 130 1.67E-37 T 29-03-2018 IPR032466 Metal-dependent hydrolase SMALA_RS33700 d071291ca707dabcd1c69139fa0962b2 548 Gene3D G3DSA:3.20.20.140 181 479 7.2E-45 T 29-03-2018 SMALA_RS27125 0b98a96edf0149bb73f452f13d0dc99d 566 Pfam PF01642 Methylmalonyl-CoA mutase 29 558 1.4E-211 T 29-03-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMALA_RS27125 0b98a96edf0149bb73f452f13d0dc99d 566 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 27 564 5.5E-198 T 29-03-2018 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMALA_RS27125 0b98a96edf0149bb73f452f13d0dc99d 566 SUPERFAMILY SSF51703 7 560 8.63E-190 T 29-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMALA_RS27125 0b98a96edf0149bb73f452f13d0dc99d 566 Gene3D G3DSA:3.20.20.240 27 560 2.7E-209 T 29-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMALA_RS43100 2477c79664655a709c88e16d906742f7 237 Gene3D G3DSA:3.40.50.300 1 234 3.2E-7 T 29-03-2018 SMALA_RS43100 2477c79664655a709c88e16d906742f7 237 SUPERFAMILY SSF52540 3 225 2.32E-6 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS08630 77a4e59d7bff8f5c15f0306ba063166f 319 Gene3D G3DSA:3.40.50.620 88 316 4.7E-5 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS08630 77a4e59d7bff8f5c15f0306ba063166f 319 Pfam PF13280 WYL domain 143 310 3.9E-28 T 29-03-2018 IPR026881 WYL domain SMALA_RS08630 77a4e59d7bff8f5c15f0306ba063166f 319 Gene3D G3DSA:1.10.10.10 1 65 9.2E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS08630 77a4e59d7bff8f5c15f0306ba063166f 319 ProSitePatterns PS00894 DeoR-type HTH domain signature. 7 41 - T 29-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 SMALA_RS08630 77a4e59d7bff8f5c15f0306ba063166f 319 SMART SM00420 7 63 0.0074 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMALA_RS08630 77a4e59d7bff8f5c15f0306ba063166f 319 SUPERFAMILY SSF46785 4 62 7.14E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS08630 77a4e59d7bff8f5c15f0306ba063166f 319 Pfam PF08279 HTH domain 7 62 6.1E-16 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 SMALA_RS10450 343cd2c92c805c93fda844cd29948123 432 SUPERFAMILY SSF52540 1 54 1.19E-28 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS10450 343cd2c92c805c93fda844cd29948123 432 SUPERFAMILY SSF52540 82 295 1.19E-28 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS10450 343cd2c92c805c93fda844cd29948123 432 Gene3D G3DSA:3.40.50.300 2 312 4.1E-46 T 29-03-2018 SMALA_RS10450 343cd2c92c805c93fda844cd29948123 432 Pfam PF02374 Anion-transporting ATPase 1 303 7.7E-30 T 29-03-2018 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 SMALA_RS29340 2b87d62fd63c124ca37a9d0f24021217 327 Pfam PF00348 Polyprenyl synthetase 41 276 2.5E-48 T 29-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 SMALA_RS29340 2b87d62fd63c124ca37a9d0f24021217 327 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 81 95 - T 29-03-2018 IPR033749 Polyprenyl synthetase, conserved site SMALA_RS29340 2b87d62fd63c124ca37a9d0f24021217 327 SUPERFAMILY SSF48576 11 326 1.55E-69 T 29-03-2018 IPR008949 Isoprenoid synthase domain SMALA_RS29340 2b87d62fd63c124ca37a9d0f24021217 327 Gene3D G3DSA:1.10.600.10 2 327 3.9E-82 T 29-03-2018 IPR008949 Isoprenoid synthase domain SMALA_RS15775 cccee2e25624e280e9ad8e09f00dcf59 401 Gene3D G3DSA:1.10.443.10 175 374 2.9E-28 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 SMALA_RS15775 cccee2e25624e280e9ad8e09f00dcf59 401 Gene3D G3DSA:3.30.160.60 8 59 2.5E-5 T 29-03-2018 SMALA_RS15775 cccee2e25624e280e9ad8e09f00dcf59 401 Gene3D G3DSA:1.10.150.130 63 174 3.5E-15 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal SMALA_RS15775 cccee2e25624e280e9ad8e09f00dcf59 401 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 69 125 7.4E-5 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 SMALA_RS15775 cccee2e25624e280e9ad8e09f00dcf59 401 Pfam PF00589 Phage integrase family 197 365 7.4E-16 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 SMALA_RS15775 cccee2e25624e280e9ad8e09f00dcf59 401 SUPERFAMILY SSF56349 68 372 7.65E-49 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 SMALA_RS26625 72896a9c2192bc5e0167c612c5a172c8 213 Gene3D G3DSA:3.40.50.300 25 211 2.4E-18 T 29-03-2018 SMALA_RS26625 72896a9c2192bc5e0167c612c5a172c8 213 SUPERFAMILY SSF52540 36 208 2.45E-21 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS26625 72896a9c2192bc5e0167c612c5a172c8 213 Pfam PF03029 Conserved hypothetical ATP binding protein 41 208 2.1E-25 T 29-03-2018 IPR004130 GPN-loop GTPase SMALA_RS18635 724fae88e2d00607973c989a828042a9 224 SUPERFAMILY SSF51206 3 142 2.62E-39 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like SMALA_RS18635 724fae88e2d00607973c989a828042a9 224 Gene3D G3DSA:2.60.120.10 1 143 3.6E-36 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SMALA_RS18635 724fae88e2d00607973c989a828042a9 224 SMART SM00419 167 215 2.1E-13 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 SMALA_RS18635 724fae88e2d00607973c989a828042a9 224 Gene3D G3DSA:1.10.10.10 144 224 6.7E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS18635 724fae88e2d00607973c989a828042a9 224 SMART SM00100 10 128 5.4E-27 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain SMALA_RS18635 724fae88e2d00607973c989a828042a9 224 Pfam PF00027 Cyclic nucleotide-binding domain 29 110 5.2E-26 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain SMALA_RS18635 724fae88e2d00607973c989a828042a9 224 ProSitePatterns PS00889 Cyclic nucleotide-binding domain signature 2. 78 95 - T 29-03-2018 IPR018488 Cyclic nucleotide-binding, conserved site SMALA_RS18635 724fae88e2d00607973c989a828042a9 224 Pfam PF13545 Crp-like helix-turn-helix domain 148 221 4.0E-17 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 SMALA_RS18635 724fae88e2d00607973c989a828042a9 224 PRINTS PR00103 cAMP-dependent protein kinase signature 31 45 2.4E-6 T 29-03-2018 SMALA_RS18635 724fae88e2d00607973c989a828042a9 224 PRINTS PR00103 cAMP-dependent protein kinase signature 46 60 2.4E-6 T 29-03-2018 SMALA_RS18635 724fae88e2d00607973c989a828042a9 224 PRINTS PR00103 cAMP-dependent protein kinase signature 76 85 2.4E-6 T 29-03-2018 SMALA_RS18635 724fae88e2d00607973c989a828042a9 224 PRINTS PR00103 cAMP-dependent protein kinase signature 88 99 2.4E-6 T 29-03-2018 SMALA_RS18635 724fae88e2d00607973c989a828042a9 224 SUPERFAMILY SSF46785 145 222 2.93E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS41670 7770598dfbeb9161b3c22d0e8468e0f6 340 Gene3D G3DSA:1.10.3720.10 31 311 2.6E-54 T 29-03-2018 SMALA_RS41670 7770598dfbeb9161b3c22d0e8468e0f6 340 SUPERFAMILY SSF161098 29 317 9.35E-57 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS41670 7770598dfbeb9161b3c22d0e8468e0f6 340 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 309 4.0E-20 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS34100 e19f61c292a563d2ded7d6850cdb3b98 404 Gene3D G3DSA:3.40.50.720 2 390 1.0E-29 T 29-03-2018 SMALA_RS34100 e19f61c292a563d2ded7d6850cdb3b98 404 Pfam PF07993 Male sterility protein 6 288 1.3E-34 T 29-03-2018 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 SMALA_RS34100 e19f61c292a563d2ded7d6850cdb3b98 404 SUPERFAMILY SSF51735 1 220 5.52E-29 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS34100 e19f61c292a563d2ded7d6850cdb3b98 404 SUPERFAMILY SSF51735 257 336 5.52E-29 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS05085 efd2a21017962457ff2a347d0e76695b 307 Gene3D G3DSA:3.90.25.10 176 296 8.1E-14 T 29-03-2018 SMALA_RS05085 efd2a21017962457ff2a347d0e76695b 307 Gene3D G3DSA:3.40.50.720 1 175 2.4E-19 T 29-03-2018 SMALA_RS05085 efd2a21017962457ff2a347d0e76695b 307 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 216 4.6E-15 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 SMALA_RS05085 efd2a21017962457ff2a347d0e76695b 307 SUPERFAMILY SSF51735 1 288 2.47E-40 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS34140 d432cfd60c3c8ee23e628a21fced766d 740 Gene3D G3DSA:3.30.450.20 433 540 1.3E-4 T 29-03-2018 SMALA_RS34140 d432cfd60c3c8ee23e628a21fced766d 740 SUPERFAMILY SSF158472 675 722 3.27E-6 T 29-03-2018 SMALA_RS34140 d432cfd60c3c8ee23e628a21fced766d 740 SMART SM00304 673 725 0.032 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMALA_RS34140 d432cfd60c3c8ee23e628a21fced766d 740 SMART SM00304 331 383 0.49 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMALA_RS42305 529de29fc49e03b668af40103cd19919 374 SUPERFAMILY SSF75011 86 306 2.35E-7 T 29-03-2018 SMALA_RS42305 529de29fc49e03b668af40103cd19919 374 Gene3D G3DSA:2.130.10.10 61 194 0.055 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMALA_RS42305 529de29fc49e03b668af40103cd19919 374 Gene3D G3DSA:2.130.10.150 195 366 2.6E-5 T 29-03-2018 SMALA_RS36735 c98d94ba6d9995430051768fcd7b1873 136 SMART SM00823 Phosphopantetheine attachment site 53 125 3.8E-8 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS36735 c98d94ba6d9995430051768fcd7b1873 136 Pfam PF00550 Phosphopantetheine attachment site 58 121 1.1E-9 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS36735 c98d94ba6d9995430051768fcd7b1873 136 SMART SM01294 57 121 0.0012 T 29-03-2018 SMALA_RS36735 c98d94ba6d9995430051768fcd7b1873 136 SUPERFAMILY SSF47336 50 125 1.31E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS36735 c98d94ba6d9995430051768fcd7b1873 136 Gene3D G3DSA:1.10.1200.10 35 126 3.7E-15 T 29-03-2018 SMALA_RS21560 908a34c107d8ed1ccf173d44632b5650 86 SMART SM00360 4 76 2.2E-25 T 29-03-2018 IPR000504 RNA recognition motif domain GO:0003676 SMALA_RS21560 908a34c107d8ed1ccf173d44632b5650 86 SUPERFAMILY SSF54928 3 82 1.01E-26 T 29-03-2018 IPR000504 RNA recognition motif domain GO:0003676 SMALA_RS21560 908a34c107d8ed1ccf173d44632b5650 86 Pfam PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 6 73 5.6E-19 T 29-03-2018 IPR000504 RNA recognition motif domain GO:0003676 SMALA_RS21560 908a34c107d8ed1ccf173d44632b5650 86 Gene3D G3DSA:3.30.70.330 1 86 1.7E-26 T 29-03-2018 SMALA_RS32945 eaa362885b166a4bfda1259b78ace901 843 SUPERFAMILY SSF55021 759 839 2.25E-15 T 29-03-2018 SMALA_RS32945 eaa362885b166a4bfda1259b78ace901 843 SUPERFAMILY SSF81301 283 508 1.96E-63 T 29-03-2018 SMALA_RS32945 eaa362885b166a4bfda1259b78ace901 843 SUPERFAMILY SSF81271 491 563 3.71E-21 T 29-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 SMALA_RS32945 eaa362885b166a4bfda1259b78ace901 843 Gene3D G3DSA:3.30.70.260 764 843 8.6E-14 T 29-03-2018 SMALA_RS32945 eaa362885b166a4bfda1259b78ace901 843 Pfam PF02824 TGS domain 504 563 1.7E-21 T 29-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 SMALA_RS32945 eaa362885b166a4bfda1259b78ace901 843 Pfam PF04607 Region found in RelA / SpoT proteins 338 447 4.3E-37 T 29-03-2018 IPR007685 RelA/SpoT GO:0015969 SMALA_RS32945 eaa362885b166a4bfda1259b78ace901 843 SMART SM00954 338 448 2.1E-64 T 29-03-2018 IPR007685 RelA/SpoT GO:0015969 SMALA_RS32945 eaa362885b166a4bfda1259b78ace901 843 Gene3D G3DSA:3.10.20.30 498 569 3.1E-24 T 29-03-2018 IPR012675 Beta-grasp domain SMALA_RS32945 eaa362885b166a4bfda1259b78ace901 843 Pfam PF13328 HD domain 131 278 2.6E-51 T 29-03-2018 IPR003607 HD/PDEase domain SMALA_RS32945 eaa362885b166a4bfda1259b78ace901 843 Pfam PF13291 ACT domain 760 836 2.7E-17 T 29-03-2018 IPR002912 ACT domain SMALA_RS32945 eaa362885b166a4bfda1259b78ace901 843 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 131 836 4.7E-258 T 29-03-2018 IPR004811 RelA/SpoT family GO:0015969 SMALA_RS32945 eaa362885b166a4bfda1259b78ace901 843 SMART SM00471 146 256 1.1E-12 T 29-03-2018 IPR003607 HD/PDEase domain SMALA_RS32945 eaa362885b166a4bfda1259b78ace901 843 SUPERFAMILY SSF109604 122 293 6.59E-71 T 29-03-2018 SMALA_RS32945 eaa362885b166a4bfda1259b78ace901 843 Gene3D G3DSA:3.30.460.10 291 429 4.7E-43 T 29-03-2018 SMALA_RS11955 0ba2dd1351b781fa57068f2cc92922d4 533 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 30 518 2.0E-88 T 29-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 SMALA_RS11955 0ba2dd1351b781fa57068f2cc92922d4 533 Gene3D G3DSA:1.20.1250.20 269 526 1.3E-31 T 29-03-2018 SMALA_RS11955 0ba2dd1351b781fa57068f2cc92922d4 533 SUPERFAMILY SSF103473 15 213 4.97E-75 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS11955 0ba2dd1351b781fa57068f2cc92922d4 533 SUPERFAMILY SSF103473 495 520 4.97E-75 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS11955 0ba2dd1351b781fa57068f2cc92922d4 533 SUPERFAMILY SSF103473 265 436 4.97E-75 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS11955 0ba2dd1351b781fa57068f2cc92922d4 533 Gene3D G3DSA:1.20.1250.20 21 215 2.8E-33 T 29-03-2018 SMALA_RS11955 0ba2dd1351b781fa57068f2cc92922d4 533 Pfam PF07690 Major Facilitator Superfamily 35 426 4.8E-57 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS22005 6b136856b0fd86f586c255e6c129d8ee 219 Gene3D G3DSA:3.40.470.10 21 219 9.3E-60 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SMALA_RS22005 6b136856b0fd86f586c255e6c129d8ee 219 Pfam PF03167 Uracil DNA glycosylase superfamily 47 211 2.4E-37 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SMALA_RS22005 6b136856b0fd86f586c255e6c129d8ee 219 SUPERFAMILY SSF52141 20 217 5.23E-52 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SMALA_RS22005 6b136856b0fd86f586c255e6c129d8ee 219 TIGRFAM TIGR03914 UDG_fam_dom: uracil-DNA glycosylase family domain 19 213 4.0E-71 T 29-03-2018 IPR005273 Uracil-DNA glycosylase family 4 SMALA_RS22005 6b136856b0fd86f586c255e6c129d8ee 219 SMART SM00986 47 212 2.7E-36 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SMALA_RS22005 6b136856b0fd86f586c255e6c129d8ee 219 SMART SM00987 47 212 2.7E-36 T 29-03-2018 SMALA_RS22005 6b136856b0fd86f586c255e6c129d8ee 219 TIGRFAM TIGR00758 UDG_fam4: uracil-DNA glycosylase, family 4 33 204 6.5E-40 T 29-03-2018 IPR005273 Uracil-DNA glycosylase family 4 SMALA_RS00085 6b136856b0fd86f586c255e6c129d8ee 219 Gene3D G3DSA:3.40.470.10 21 219 9.3E-60 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SMALA_RS00085 6b136856b0fd86f586c255e6c129d8ee 219 Pfam PF03167 Uracil DNA glycosylase superfamily 47 211 2.4E-37 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SMALA_RS00085 6b136856b0fd86f586c255e6c129d8ee 219 SUPERFAMILY SSF52141 20 217 5.23E-52 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SMALA_RS00085 6b136856b0fd86f586c255e6c129d8ee 219 TIGRFAM TIGR03914 UDG_fam_dom: uracil-DNA glycosylase family domain 19 213 4.0E-71 T 29-03-2018 IPR005273 Uracil-DNA glycosylase family 4 SMALA_RS00085 6b136856b0fd86f586c255e6c129d8ee 219 SMART SM00986 47 212 2.7E-36 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SMALA_RS00085 6b136856b0fd86f586c255e6c129d8ee 219 SMART SM00987 47 212 2.7E-36 T 29-03-2018 SMALA_RS00085 6b136856b0fd86f586c255e6c129d8ee 219 TIGRFAM TIGR00758 UDG_fam4: uracil-DNA glycosylase, family 4 33 204 6.5E-40 T 29-03-2018 IPR005273 Uracil-DNA glycosylase family 4 SMALA_RS34960 5253ed87348fd131323329906c8c5980 702 Pfam PF00989 PAS fold 26 126 3.7E-8 T 29-03-2018 IPR013767 PAS fold GO:0006355 SMALA_RS34960 5253ed87348fd131323329906c8c5980 702 Gene3D G3DSA:3.60.40.10 457 688 1.9E-39 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS34960 5253ed87348fd131323329906c8c5980 702 SUPERFAMILY SSF55785 25 129 8.55E-18 T 29-03-2018 IPR000014 PAS domain SMALA_RS34960 5253ed87348fd131323329906c8c5980 702 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 30 129 1.3E-11 T 29-03-2018 IPR000014 PAS domain SMALA_RS34960 5253ed87348fd131323329906c8c5980 702 SMART SM00091 141 207 0.22 T 29-03-2018 IPR000014 PAS domain SMALA_RS34960 5253ed87348fd131323329906c8c5980 702 SMART SM00091 20 87 1.8E-4 T 29-03-2018 IPR000014 PAS domain SMALA_RS34960 5253ed87348fd131323329906c8c5980 702 SUPERFAMILY SSF55785 144 256 5.23E-11 T 29-03-2018 IPR000014 PAS domain SMALA_RS34960 5253ed87348fd131323329906c8c5980 702 SUPERFAMILY SSF81606 492 686 3.14E-5 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS34960 5253ed87348fd131323329906c8c5980 702 Gene3D G3DSA:3.30.450.40 263 456 1.0E-37 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS34960 5253ed87348fd131323329906c8c5980 702 SUPERFAMILY SSF55781 354 463 3.05E-19 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS34960 5253ed87348fd131323329906c8c5980 702 SMART SM00331 478 686 4.4E-38 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS34960 5253ed87348fd131323329906c8c5980 702 Pfam PF01590 GAF domain 294 450 5.2E-13 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS34960 5253ed87348fd131323329906c8c5980 702 Gene3D G3DSA:3.30.450.20 24 129 9.0E-19 T 29-03-2018 SMALA_RS34960 5253ed87348fd131323329906c8c5980 702 Pfam PF08448 PAS fold 148 260 4.8E-21 T 29-03-2018 IPR013656 PAS fold-4 SMALA_RS34960 5253ed87348fd131323329906c8c5980 702 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 505 686 8.6E-50 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS34960 5253ed87348fd131323329906c8c5980 702 Gene3D G3DSA:3.30.450.20 132 262 3.0E-17 T 29-03-2018 SMALA_RS34960 5253ed87348fd131323329906c8c5980 702 SMART SM00065 283 460 7.3E-13 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS15980 43935c39269643f5eb934d66d3e85719 416 SMART SM00387 309 410 1.6E-12 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS15980 43935c39269643f5eb934d66d3e85719 416 Gene3D G3DSA:1.10.287.130 192 263 1.0E-9 T 29-03-2018 SMALA_RS15980 43935c39269643f5eb934d66d3e85719 416 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 312 394 4.7E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS15980 43935c39269643f5eb934d66d3e85719 416 SMART SM00388 202 267 9.3E-9 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS15980 43935c39269643f5eb934d66d3e85719 416 PRINTS PR00344 Bacterial sensor protein C-terminal signature 344 358 2.7E-7 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS15980 43935c39269643f5eb934d66d3e85719 416 PRINTS PR00344 Bacterial sensor protein C-terminal signature 372 390 2.7E-7 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS15980 43935c39269643f5eb934d66d3e85719 416 SUPERFAMILY SSF47384 186 263 3.92E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS15980 43935c39269643f5eb934d66d3e85719 416 Pfam PF00512 His Kinase A (phospho-acceptor) domain 203 263 3.1E-9 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS15980 43935c39269643f5eb934d66d3e85719 416 Gene3D G3DSA:3.30.565.10 270 408 1.4E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS15980 43935c39269643f5eb934d66d3e85719 416 SUPERFAMILY SSF55874 270 398 1.26E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS19350 b7106933b7e8af62750ba8a8608fe4df 236 Pfam PF07729 FCD domain 94 223 1.3E-22 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS19350 b7106933b7e8af62750ba8a8608fe4df 236 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 4.3E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS19350 b7106933b7e8af62750ba8a8608fe4df 236 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 4.3E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS19350 b7106933b7e8af62750ba8a8608fe4df 236 SUPERFAMILY SSF48008 91 229 2.01E-25 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS19350 b7106933b7e8af62750ba8a8608fe4df 236 SMART SM00345 15 74 3.7E-19 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS19350 b7106933b7e8af62750ba8a8608fe4df 236 SMART SM00895 94 224 1.2E-21 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS19350 b7106933b7e8af62750ba8a8608fe4df 236 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 2.0E-19 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS19350 b7106933b7e8af62750ba8a8608fe4df 236 Gene3D G3DSA:1.20.120.530 87 236 2.2E-28 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS19350 b7106933b7e8af62750ba8a8608fe4df 236 Gene3D G3DSA:1.10.10.10 3 76 3.4E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS19350 b7106933b7e8af62750ba8a8608fe4df 236 SUPERFAMILY SSF46785 6 78 4.9E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS33230 b796577ad936a18c86db8c87beb0304d 490 Pfam PF13520 Amino acid permease 53 453 3.1E-53 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMALA_RS33230 b796577ad936a18c86db8c87beb0304d 490 TIGRFAM TIGR00909 2A0306: amino acid transporter 48 478 6.9E-176 T 29-03-2018 IPR004758 Amino acid transporter SMALA_RS33230 b796577ad936a18c86db8c87beb0304d 490 PIRSF PIRSF006060 36 488 3.7E-89 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMALA_RS18640 4c50e7246bcc3de3a8b86e14fe15d32f 276 SMART SM00849 39 204 1.6E-24 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS18640 4c50e7246bcc3de3a8b86e14fe15d32f 276 Gene3D G3DSA:3.60.15.10 34 271 4.4E-38 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS18640 4c50e7246bcc3de3a8b86e14fe15d32f 276 Pfam PF00753 Metallo-beta-lactamase superfamily 36 204 4.6E-14 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS18640 4c50e7246bcc3de3a8b86e14fe15d32f 276 SUPERFAMILY SSF56281 22 275 8.54E-50 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS28735 5fe8953a0abf44d66fa1e5679685a4a1 948 Pfam PF01580 FtsK/SpoIIIE family 571 769 1.6E-54 T 29-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 SMALA_RS28735 5fe8953a0abf44d66fa1e5679685a4a1 948 Gene3D G3DSA:1.10.10.10 870 924 1.4E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS28735 5fe8953a0abf44d66fa1e5679685a4a1 948 SMART SM00382 604 802 5.2E-5 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS28735 5fe8953a0abf44d66fa1e5679685a4a1 948 Gene3D G3DSA:3.40.50.300 459 827 1.1E-45 T 29-03-2018 SMALA_RS28735 5fe8953a0abf44d66fa1e5679685a4a1 948 SMART SM00843 869 933 5.4E-31 T 29-03-2018 IPR018541 FtsK gamma domain SMALA_RS28735 5fe8953a0abf44d66fa1e5679685a4a1 948 SUPERFAMILY SSF46785 870 935 1.5E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS28735 5fe8953a0abf44d66fa1e5679685a4a1 948 SUPERFAMILY SSF52540 542 841 1.46E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS28735 5fe8953a0abf44d66fa1e5679685a4a1 948 Pfam PF09397 Ftsk gamma domain 873 930 8.1E-23 T 29-03-2018 IPR018541 FtsK gamma domain SMALA_RS38665 970ce6a7bed924302b7297342956eae5 151 Pfam PF12802 MarR family 36 91 6.7E-12 T 29-03-2018 SMALA_RS38665 970ce6a7bed924302b7297342956eae5 151 Gene3D G3DSA:1.10.287.100 110 142 8.6E-6 T 29-03-2018 SMALA_RS38665 970ce6a7bed924302b7297342956eae5 151 SMART SM00347 26 127 4.6E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS38665 970ce6a7bed924302b7297342956eae5 151 ProSitePatterns PS01117 MarR-type HTH domain signature. 66 100 - T 29-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site SMALA_RS38665 970ce6a7bed924302b7297342956eae5 151 Gene3D G3DSA:1.10.10.10 4 109 2.3E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS38665 970ce6a7bed924302b7297342956eae5 151 SUPERFAMILY SSF46785 11 145 5.89E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS38540 55457d7a54f060b4c2f63c2447a4040b 268 SMART SM00346 16 109 0.0016 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMALA_RS38540 55457d7a54f060b4c2f63c2447a4040b 268 Pfam PF01614 Bacterial transcriptional regulator 137 248 5.1E-15 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal SMALA_RS38540 55457d7a54f060b4c2f63c2447a4040b 268 Pfam PF09339 IclR helix-turn-helix domain 20 73 5.4E-5 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMALA_RS38540 55457d7a54f060b4c2f63c2447a4040b 268 SUPERFAMILY SSF46785 19 88 4.32E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS38540 55457d7a54f060b4c2f63c2447a4040b 268 SUPERFAMILY SSF55781 78 255 1.05E-36 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS38540 55457d7a54f060b4c2f63c2447a4040b 268 Gene3D G3DSA:3.30.450.40 93 260 1.1E-38 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS38540 55457d7a54f060b4c2f63c2447a4040b 268 Gene3D G3DSA:1.10.10.10 2 81 7.6E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS24060 1caa4b1efd4476f0cdbab7f55c6672a1 485 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 6 463 40.533 T 29-03-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 SMALA_RS24060 1caa4b1efd4476f0cdbab7f55c6672a1 485 Pfam PF12804 MobA-like NTP transferase domain 9 142 2.1E-21 T 29-03-2018 IPR025877 MobA-like NTP transferase SMALA_RS24060 1caa4b1efd4476f0cdbab7f55c6672a1 485 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 8 465 1.3E-166 T 29-03-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 SMALA_RS24060 1caa4b1efd4476f0cdbab7f55c6672a1 485 Gene3D G3DSA:3.90.550.10 2 263 2.3E-59 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS24060 1caa4b1efd4476f0cdbab7f55c6672a1 485 Gene3D G3DSA:2.160.10.10 264 452 9.8E-47 T 29-03-2018 SMALA_RS24060 1caa4b1efd4476f0cdbab7f55c6672a1 485 SUPERFAMILY SSF51161 260 477 7.96E-43 T 29-03-2018 IPR011004 Trimeric LpxA-like SMALA_RS24060 1caa4b1efd4476f0cdbab7f55c6672a1 485 SUPERFAMILY SSF53448 8 264 1.04E-60 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS24060 1caa4b1efd4476f0cdbab7f55c6672a1 485 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 405 440 6.6E-7 T 29-03-2018 IPR001451 Hexapeptide repeat SMALA_RS15325 06998003190f09fee68189fb97431e6d 298 SUPERFAMILY SSF161098 20 292 4.95E-69 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS15325 06998003190f09fee68189fb97431e6d 298 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 103 289 1.3E-19 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS15325 06998003190f09fee68189fb97431e6d 298 Gene3D G3DSA:1.10.3720.10 13 286 3.9E-47 T 29-03-2018 SMALA_RS05930 ef519313c926d699ac5331e601219bd2 369 Gene3D G3DSA:2.102.10.10 36 138 8.8E-22 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMALA_RS05930 ef519313c926d699ac5331e601219bd2 369 Gene3D G3DSA:3.90.380.10 139 351 6.5E-19 T 29-03-2018 SMALA_RS05930 ef519313c926d699ac5331e601219bd2 369 Pfam PF00355 Rieske [2Fe-2S] domain 40 131 2.3E-14 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMALA_RS05930 ef519313c926d699ac5331e601219bd2 369 SUPERFAMILY SSF55961 153 350 1.98E-8 T 29-03-2018 SMALA_RS05930 ef519313c926d699ac5331e601219bd2 369 SUPERFAMILY SSF50022 36 145 2.36E-28 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMALA_RS04295 9ee76bb3c07bd0d88068f750d66f7d75 317 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 312 7.7E-27 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS04295 9ee76bb3c07bd0d88068f750d66f7d75 317 Gene3D G3DSA:1.10.3720.10 3 303 1.6E-29 T 29-03-2018 SMALA_RS04295 9ee76bb3c07bd0d88068f750d66f7d75 317 SUPERFAMILY SSF161098 92 299 2.75E-13 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS38675 d3a3ad85e27965b91322a03c28144668 289 Pfam PF01061 ABC-2 type transporter 46 255 1.0E-35 T 29-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 SMALA_RS38675 d3a3ad85e27965b91322a03c28144668 289 PIRSF PIRSF006648 20 288 3.3E-62 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMALA_RS38675 d3a3ad85e27965b91322a03c28144668 289 PRINTS PR00164 ABC-2 type transport system membrane protein signature 93 115 8.5E-8 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMALA_RS38675 d3a3ad85e27965b91322a03c28144668 289 PRINTS PR00164 ABC-2 type transport system membrane protein signature 213 232 8.5E-8 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMALA_RS38675 d3a3ad85e27965b91322a03c28144668 289 PRINTS PR00164 ABC-2 type transport system membrane protein signature 176 200 8.5E-8 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMALA_RS38675 d3a3ad85e27965b91322a03c28144668 289 PRINTS PR00164 ABC-2 type transport system membrane protein signature 233 252 8.5E-8 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMALA_RS03435 e991a026aa0c052e768715ef55194296 270 Gene3D G3DSA:1.10.3720.10 1 260 2.8E-38 T 29-03-2018 SMALA_RS03435 e991a026aa0c052e768715ef55194296 270 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 260 1.3E-14 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS03435 e991a026aa0c052e768715ef55194296 270 SUPERFAMILY SSF161098 5 261 7.59E-51 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS21770 ec5662ed0252d778b10977e125f40753 390 PRINTS PR01272 Acetoin utilisation ACUC protein signature 105 118 9.2E-7 T 29-03-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 SMALA_RS21770 ec5662ed0252d778b10977e125f40753 390 PRINTS PR01272 Acetoin utilisation ACUC protein signature 16 36 9.2E-7 T 29-03-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 SMALA_RS21770 ec5662ed0252d778b10977e125f40753 390 PRINTS PR01272 Acetoin utilisation ACUC protein signature 84 98 9.2E-7 T 29-03-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 SMALA_RS21770 ec5662ed0252d778b10977e125f40753 390 Gene3D G3DSA:3.40.800.20 3 372 3.1E-93 T 29-03-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 SMALA_RS21770 ec5662ed0252d778b10977e125f40753 390 SUPERFAMILY SSF52768 6 345 1.49E-100 T 29-03-2018 SMALA_RS21770 ec5662ed0252d778b10977e125f40753 390 PRINTS PR01270 Histone deacetylase superfamily signature 161 176 1.6E-17 T 29-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 SMALA_RS21770 ec5662ed0252d778b10977e125f40753 390 PRINTS PR01270 Histone deacetylase superfamily signature 247 257 1.6E-17 T 29-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 SMALA_RS21770 ec5662ed0252d778b10977e125f40753 390 PRINTS PR01270 Histone deacetylase superfamily signature 128 151 1.6E-17 T 29-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 SMALA_RS21770 ec5662ed0252d778b10977e125f40753 390 Pfam PF00850 Histone deacetylase domain 22 317 9.1E-69 T 29-03-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 SMALA_RS17665 754a7b6c2dd68d3b5d610ebee97e8a87 466 Gene3D G3DSA:1.20.120.640 304 395 1.7E-20 T 29-03-2018 SMALA_RS17665 754a7b6c2dd68d3b5d610ebee97e8a87 466 SUPERFAMILY SSF52374 4 310 5.36E-86 T 29-03-2018 SMALA_RS17665 754a7b6c2dd68d3b5d610ebee97e8a87 466 Gene3D G3DSA:3.40.50.620 1 303 4.2E-82 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS17665 754a7b6c2dd68d3b5d610ebee97e8a87 466 SUPERFAMILY SSF47323 330 463 4.05E-32 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMALA_RS17665 754a7b6c2dd68d3b5d610ebee97e8a87 466 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 62 71 2.8E-27 T 29-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 SMALA_RS17665 754a7b6c2dd68d3b5d610ebee97e8a87 466 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 190 208 2.8E-27 T 29-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 SMALA_RS17665 754a7b6c2dd68d3b5d610ebee97e8a87 466 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 221 242 2.8E-27 T 29-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 SMALA_RS17665 754a7b6c2dd68d3b5d610ebee97e8a87 466 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 26 37 2.8E-27 T 29-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 SMALA_RS17665 754a7b6c2dd68d3b5d610ebee97e8a87 466 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 4 462 4.1E-138 T 29-03-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 SMALA_RS17665 754a7b6c2dd68d3b5d610ebee97e8a87 466 SMART SM00840 341 402 1.6E-15 T 29-03-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 SMALA_RS17665 754a7b6c2dd68d3b5d610ebee97e8a87 466 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 3 464 35.226 T 29-03-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 SMALA_RS17665 754a7b6c2dd68d3b5d610ebee97e8a87 466 Pfam PF09190 DALR domain 341 394 6.2E-11 T 29-03-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 SMALA_RS17665 754a7b6c2dd68d3b5d610ebee97e8a87 466 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 17 311 4.6E-117 T 29-03-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 SMALA_RS09250 1777e027f0ddcf922dae971804066378 134 Gene3D G3DSA:2.60.120.10 9 130 1.0E-15 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SMALA_RS09250 1777e027f0ddcf922dae971804066378 134 Hamap MF_01255 L-ectoine synthase [ectC]. 1 129 39.068 T 29-03-2018 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108|KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SMALA_RS09250 1777e027f0ddcf922dae971804066378 134 SUPERFAMILY SSF51182 3 128 5.09E-20 T 29-03-2018 IPR011051 RmlC-like cupin domain SMALA_RS09250 1777e027f0ddcf922dae971804066378 134 ProDom PD080544 SYNTHASE 4.2.1.- LYASE L-ECTOINE DEHYDRATASE N-ACETYLDIAMINOBUTYRATE ECTOINE ENZYME SYNTHASE:ECTOINE ECTC 1 119 1.0E-61 T 29-03-2018 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108|KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SMALA_RS09250 1777e027f0ddcf922dae971804066378 134 Pfam PF06339 Ectoine synthase 2 127 2.0E-56 T 29-03-2018 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108|KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SMALA_RS29100 fcd41e7d70c89be25a53908eb06a05a7 455 SUPERFAMILY SSF63411 16 223 1.83E-59 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 SMALA_RS29100 fcd41e7d70c89be25a53908eb06a05a7 455 Pfam PF05193 Peptidase M16 inactive domain 185 363 1.3E-29 T 29-03-2018 IPR007863 Peptidase M16, C-terminal SMALA_RS29100 fcd41e7d70c89be25a53908eb06a05a7 455 Gene3D G3DSA:3.30.830.10 13 237 1.2E-63 T 29-03-2018 SMALA_RS29100 fcd41e7d70c89be25a53908eb06a05a7 455 SUPERFAMILY SSF63411 249 439 4.83E-28 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 SMALA_RS29100 fcd41e7d70c89be25a53908eb06a05a7 455 Pfam PF00675 Insulinase (Peptidase family M16) 26 164 2.9E-21 T 29-03-2018 IPR011765 Peptidase M16, N-terminal SMALA_RS29100 fcd41e7d70c89be25a53908eb06a05a7 455 Gene3D G3DSA:3.30.830.10 244 447 5.2E-28 T 29-03-2018 SMALA_RS12090 fd1f52844a72f3f531fbb251c9b5bebf 343 SMART SM00829 12 337 2.1E-6 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS12090 fd1f52844a72f3f531fbb251c9b5bebf 343 Gene3D G3DSA:3.90.180.10 6 151 1.9E-39 T 29-03-2018 SMALA_RS12090 fd1f52844a72f3f531fbb251c9b5bebf 343 Gene3D G3DSA:3.40.50.720 152 312 1.5E-23 T 29-03-2018 SMALA_RS12090 fd1f52844a72f3f531fbb251c9b5bebf 343 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 64 78 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 SMALA_RS12090 fd1f52844a72f3f531fbb251c9b5bebf 343 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 137 2.9E-25 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS12090 fd1f52844a72f3f531fbb251c9b5bebf 343 SUPERFAMILY SSF50129 7 177 1.83E-44 T 29-03-2018 IPR011032 GroES-like SMALA_RS12090 fd1f52844a72f3f531fbb251c9b5bebf 343 SUPERFAMILY SSF51735 146 306 8.78E-27 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS12090 fd1f52844a72f3f531fbb251c9b5bebf 343 Pfam PF00107 Zinc-binding dehydrogenase 179 296 6.8E-15 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMALA_RS08265 0821b8ce861f9d5d8f9e047caa12ba4f 742 Gene3D G3DSA:2.20.25.90 1 59 1.3E-12 T 29-03-2018 SMALA_RS08265 0821b8ce861f9d5d8f9e047caa12ba4f 742 SMART SM00926 1 54 2.5E-12 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS08265 0821b8ce861f9d5d8f9e047caa12ba4f 742 Gene3D G3DSA:2.40.40.20 476 740 2.1E-29 T 29-03-2018 SMALA_RS08265 0821b8ce861f9d5d8f9e047caa12ba4f 742 Gene3D G3DSA:3.40.50.740 60 147 1.1E-12 T 29-03-2018 SMALA_RS08265 0821b8ce861f9d5d8f9e047caa12ba4f 742 SUPERFAMILY SSF53706 4 480 2.88E-113 T 29-03-2018 SMALA_RS08265 0821b8ce861f9d5d8f9e047caa12ba4f 742 SUPERFAMILY SSF50692 613 738 1.47E-29 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain SMALA_RS08265 0821b8ce861f9d5d8f9e047caa12ba4f 742 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 7 49 1.2E-8 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS08265 0821b8ce861f9d5d8f9e047caa12ba4f 742 Pfam PF01568 Molydopterin dinucleotide binding domain 613 728 3.2E-22 T 29-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 SMALA_RS08265 0821b8ce861f9d5d8f9e047caa12ba4f 742 Gene3D G3DSA:3.40.228.10 386 475 7.2E-11 T 29-03-2018 SMALA_RS08265 0821b8ce861f9d5d8f9e047caa12ba4f 742 Pfam PF00384 Molybdopterin oxidoreductase 58 433 3.6E-30 T 29-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS08265 0821b8ce861f9d5d8f9e047caa12ba4f 742 Gene3D G3DSA:3.40.228.10 148 385 4.6E-57 T 29-03-2018 SMALA_RS17025 074216bb9a7091191e27daeb9ec3cde8 196 SUPERFAMILY SSF52980 12 179 7.51E-21 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 SMALA_RS17025 074216bb9a7091191e27daeb9ec3cde8 196 Gene3D G3DSA:3.90.1570.10 14 195 1.5E-31 T 29-03-2018 SMALA_RS17025 074216bb9a7091191e27daeb9ec3cde8 196 Pfam PF05685 Putative restriction endonuclease 22 183 2.4E-25 T 29-03-2018 IPR008538 Domain of unknown function DUF820 SMALA_RS25870 abe056727a01e5d8b7abecc70aab2d4f 366 SUPERFAMILY SSF143865 28 297 4.58E-65 T 29-03-2018 SMALA_RS25870 abe056727a01e5d8b7abecc70aab2d4f 366 Gene3D G3DSA:1.20.58.340 299 366 1.4E-19 T 29-03-2018 SMALA_RS25870 abe056727a01e5d8b7abecc70aab2d4f 366 Pfam PF01544 CorA-like Mg2+ transporter protein 66 356 2.1E-63 T 29-03-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 SMALA_RS25870 abe056727a01e5d8b7abecc70aab2d4f 366 SUPERFAMILY SSF144083 302 363 7.32E-20 T 29-03-2018 SMALA_RS25870 abe056727a01e5d8b7abecc70aab2d4f 366 Gene3D G3DSA:1.20.58.340 178 298 7.1E-34 T 29-03-2018 SMALA_RS25870 abe056727a01e5d8b7abecc70aab2d4f 366 Gene3D G3DSA:3.30.460.20 22 171 1.9E-38 T 29-03-2018 SMALA_RS03750 814b6217c089eb9a28315d527245201d 392 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 119 2.1E-26 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS03750 814b6217c089eb9a28315d527245201d 392 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 228 381 8.4E-31 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMALA_RS03750 814b6217c089eb9a28315d527245201d 392 Gene3D G3DSA:1.20.140.10 216 392 6.8E-33 T 29-03-2018 SMALA_RS03750 814b6217c089eb9a28315d527245201d 392 Gene3D G3DSA:2.40.110.10 121 215 7.4E-32 T 29-03-2018 SMALA_RS03750 814b6217c089eb9a28315d527245201d 392 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 205 2.8E-20 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 SMALA_RS03750 814b6217c089eb9a28315d527245201d 392 SUPERFAMILY SSF56645 2 241 4.45E-71 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMALA_RS03750 814b6217c089eb9a28315d527245201d 392 Gene3D G3DSA:1.10.540.10 2 120 3.3E-32 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS03750 814b6217c089eb9a28315d527245201d 392 SUPERFAMILY SSF47203 228 388 1.5E-25 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMALA_RS16880 a2c8b8f3b452c5ecb05894f016f0fa5d 294 PIRSF PIRSF001553 1 293 9.9E-115 T 29-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 SMALA_RS16880 a2c8b8f3b452c5ecb05894f016f0fa5d 294 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 3 290 2.5E-127 T 29-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 SMALA_RS16880 a2c8b8f3b452c5ecb05894f016f0fa5d 294 Pfam PF00549 CoA-ligase 158 275 1.3E-13 T 29-03-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMALA_RS16880 a2c8b8f3b452c5ecb05894f016f0fa5d 294 Gene3D G3DSA:3.40.50.261 126 294 4.1E-49 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMALA_RS16880 a2c8b8f3b452c5ecb05894f016f0fa5d 294 SUPERFAMILY SSF51735 1 128 7.9E-36 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS16880 a2c8b8f3b452c5ecb05894f016f0fa5d 294 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 240 253 - T 29-03-2018 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site SMALA_RS16880 a2c8b8f3b452c5ecb05894f016f0fa5d 294 PRINTS PR01798 Succinyl-CoA synthase signature 86 103 4.2E-34 T 29-03-2018 SMALA_RS16880 a2c8b8f3b452c5ecb05894f016f0fa5d 294 PRINTS PR01798 Succinyl-CoA synthase signature 212 225 4.2E-34 T 29-03-2018 SMALA_RS16880 a2c8b8f3b452c5ecb05894f016f0fa5d 294 PRINTS PR01798 Succinyl-CoA synthase signature 181 199 4.2E-34 T 29-03-2018 SMALA_RS16880 a2c8b8f3b452c5ecb05894f016f0fa5d 294 PRINTS PR01798 Succinyl-CoA synthase signature 244 261 4.2E-34 T 29-03-2018 SMALA_RS16880 a2c8b8f3b452c5ecb05894f016f0fa5d 294 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 1 292 39.108 T 29-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 SMALA_RS16880 a2c8b8f3b452c5ecb05894f016f0fa5d 294 SMART SM00881 4 104 1.6E-31 T 29-03-2018 IPR003781 CoA-binding GO:0048037 SMALA_RS16880 a2c8b8f3b452c5ecb05894f016f0fa5d 294 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 158 185 - T 29-03-2018 IPR033847 ATP-citrate lyase/succinyl-CoA ligase, conserved site SMALA_RS16880 a2c8b8f3b452c5ecb05894f016f0fa5d 294 Pfam PF02629 CoA binding domain 6 103 2.1E-26 T 29-03-2018 IPR003781 CoA-binding GO:0048037 SMALA_RS16880 a2c8b8f3b452c5ecb05894f016f0fa5d 294 SUPERFAMILY SSF52210 129 290 2.49E-47 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMALA_RS16880 a2c8b8f3b452c5ecb05894f016f0fa5d 294 Gene3D G3DSA:3.40.50.720 1 125 4.1E-41 T 29-03-2018 SMALA_RS35205 9f4a4fdfa71ff73c0f583b99edaa0574 231 Gene3D G3DSA:1.10.10.10 137 227 4.8E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS35205 9f4a4fdfa71ff73c0f583b99edaa0574 231 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 194 206 5.5E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS35205 9f4a4fdfa71ff73c0f583b99edaa0574 231 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 178 194 5.5E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS35205 9f4a4fdfa71ff73c0f583b99edaa0574 231 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 178 5.5E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS35205 9f4a4fdfa71ff73c0f583b99edaa0574 231 SMART SM00448 12 125 2.0E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS35205 9f4a4fdfa71ff73c0f583b99edaa0574 231 SMART SM00421 161 218 4.2E-27 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS35205 9f4a4fdfa71ff73c0f583b99edaa0574 231 ProSitePatterns PS00622 LuxR-type HTH domain signature. 178 205 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS35205 9f4a4fdfa71ff73c0f583b99edaa0574 231 Pfam PF00072 Response regulator receiver domain 14 125 3.0E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS35205 9f4a4fdfa71ff73c0f583b99edaa0574 231 Pfam PF00196 Bacterial regulatory proteins, luxR family 164 218 3.5E-19 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS35205 9f4a4fdfa71ff73c0f583b99edaa0574 231 SUPERFAMILY SSF46894 152 219 3.4E-21 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS35205 9f4a4fdfa71ff73c0f583b99edaa0574 231 Gene3D G3DSA:3.40.50.2300 11 136 5.6E-31 T 29-03-2018 SMALA_RS35205 9f4a4fdfa71ff73c0f583b99edaa0574 231 SUPERFAMILY SSF52172 11 142 1.04E-29 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS24965 70b4723a2673f30ed1a97f0c22f655fb 341 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 9 287 7.4E-96 T 29-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 SMALA_RS24965 70b4723a2673f30ed1a97f0c22f655fb 341 Pfam PF02401 LytB protein 9 286 2.2E-88 T 29-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 SMALA_RS24965 70b4723a2673f30ed1a97f0c22f655fb 341 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 7 290 36.461 T 29-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 SMALA_RS11950 0949844c8d83b48e4cc745cf66eef4fd 123 Gene3D G3DSA:2.60.20.30 32 105 4.3E-4 T 29-03-2018 IPR015791 Antimicrobial/protein inhibitor, gamma-crystallin-like SMALA_RS11950 0949844c8d83b48e4cc745cf66eef4fd 123 Pfam PF03995 Peptidase inhibitor family I36 29 97 5.6E-10 T 29-03-2018 SMALA_RS00960 9736dbce362a179028f2912b4b63da62 355 Gene3D G3DSA:2.60.200.30 168 292 9.8E-27 T 29-03-2018 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 SMALA_RS00960 9736dbce362a179028f2912b4b63da62 355 Gene3D G3DSA:3.40.50.10330 1 140 3.8E-25 T 29-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 SMALA_RS00960 9736dbce362a179028f2912b4b63da62 355 Pfam PF01513 ATP-NAD kinase 54 301 1.7E-43 T 29-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 SMALA_RS00960 9736dbce362a179028f2912b4b63da62 355 Hamap MF_00361 NAD kinase [nadK]. 4 317 27.789 T 29-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 SMALA_RS00960 9736dbce362a179028f2912b4b63da62 355 SUPERFAMILY SSF111331 169 317 2.09E-62 T 29-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain SMALA_RS00960 9736dbce362a179028f2912b4b63da62 355 SUPERFAMILY SSF111331 6 134 2.09E-62 T 29-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain SMALA_RS12655 2400c559c625ec43a2cc09461ef462e3 415 Gene3D G3DSA:3.40.50.1820 2 401 8.3E-11 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS12655 2400c559c625ec43a2cc09461ef462e3 415 SUPERFAMILY SSF53474 273 377 4.59E-7 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS37060 089c2ab06cb18c0f8d20d27d5b9acdf8 520 Pfam PF04984 Phage tail sheath protein subtilisin-like domain 237 402 9.6E-34 T 29-03-2018 IPR035089 Tail sheath protein, subtilisin-like domain SMALA_RS37060 089c2ab06cb18c0f8d20d27d5b9acdf8 520 Pfam PF17482 Phage tail sheath C-terminal domain 404 508 5.1E-20 T 29-03-2018 IPR020287 Tail sheath protein, C-terminal domain SMALA_RS23250 97f73fa418c5599237e802719556a56b 260 Gene3D G3DSA:3.40.50.720 1 260 2.9E-59 T 29-03-2018 SMALA_RS23250 97f73fa418c5599237e802719556a56b 260 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 256 6.9E-48 T 29-03-2018 SMALA_RS23250 97f73fa418c5599237e802719556a56b 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 8.6E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS23250 97f73fa418c5599237e802719556a56b 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 8.6E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS23250 97f73fa418c5599237e802719556a56b 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 8.6E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS23250 97f73fa418c5599237e802719556a56b 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 8.6E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS23250 97f73fa418c5599237e802719556a56b 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 221 241 8.6E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS23250 97f73fa418c5599237e802719556a56b 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 8.6E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS23250 97f73fa418c5599237e802719556a56b 260 SUPERFAMILY SSF51735 4 259 2.95E-63 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS29355 73c7e3428ff79237680f64e75510015d 276 Gene3D G3DSA:3.30.2140.10 157 274 1.1E-18 T 29-03-2018 SMALA_RS29355 73c7e3428ff79237680f64e75510015d 276 Gene3D G3DSA:3.30.2140.10 7 149 4.4E-32 T 29-03-2018 SMALA_RS29355 73c7e3428ff79237680f64e75510015d 276 SUPERFAMILY SSF54001 10 269 6.87E-64 T 29-03-2018 SMALA_RS29355 73c7e3428ff79237680f64e75510015d 276 Pfam PF00797 N-acetyltransferase 29 262 8.1E-53 T 29-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 SMALA_RS06250 d2c318b9649d0bb67387c10ea8dc5f52 314 SUPERFAMILY SSF51735 13 261 2.94E-46 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS06250 d2c318b9649d0bb67387c10ea8dc5f52 314 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 138 154 3.2E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS06250 d2c318b9649d0bb67387c10ea8dc5f52 314 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 93 104 3.2E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS06250 d2c318b9649d0bb67387c10ea8dc5f52 314 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 17 34 3.2E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS06250 d2c318b9649d0bb67387c10ea8dc5f52 314 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 199 216 3.2E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS06250 d2c318b9649d0bb67387c10ea8dc5f52 314 Gene3D G3DSA:3.40.50.720 6 313 7.2E-50 T 29-03-2018 SMALA_RS06250 d2c318b9649d0bb67387c10ea8dc5f52 314 Pfam PF00106 short chain dehydrogenase 17 217 2.4E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40695 7dc74a57b35f1aee99e594a4aa9ca513 354 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 138 3.4E-19 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS40695 7dc74a57b35f1aee99e594a4aa9ca513 354 SUPERFAMILY SSF51735 142 307 7.04E-17 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS40695 7dc74a57b35f1aee99e594a4aa9ca513 354 SMART SM00829 10 341 4.2E-5 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS40695 7dc74a57b35f1aee99e594a4aa9ca513 354 Gene3D G3DSA:3.90.180.10 1 163 1.6E-43 T 29-03-2018 SMALA_RS40695 7dc74a57b35f1aee99e594a4aa9ca513 354 SUPERFAMILY SSF50129 1 176 2.2E-41 T 29-03-2018 IPR011032 GroES-like SMALA_RS40695 7dc74a57b35f1aee99e594a4aa9ca513 354 Gene3D G3DSA:3.40.50.720 164 290 3.6E-13 T 29-03-2018 SMALA_RS13820 ced7d34415958fbd4bdcd76688a735dd 414 Pfam PF07730 Histidine kinase 208 275 1.8E-16 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMALA_RS13820 ced7d34415958fbd4bdcd76688a735dd 414 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 318 405 2.6E-6 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS13820 ced7d34415958fbd4bdcd76688a735dd 414 SMART SM00387 313 406 7.5E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS13820 ced7d34415958fbd4bdcd76688a735dd 414 PIRSF PIRSF037434 25 410 2.9E-80 T 29-03-2018 IPR017205 Signal transduction histidine kinase, ChrS SMALA_RS13820 ced7d34415958fbd4bdcd76688a735dd 414 Gene3D G3DSA:3.30.565.10 177 405 2.1E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS13820 ced7d34415958fbd4bdcd76688a735dd 414 SUPERFAMILY SSF55874 281 403 5.63E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS13490 3450773a2490858492427e27164dbd5f 301 SUPERFAMILY SSF53335 66 181 2.67E-26 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS13490 3450773a2490858492427e27164dbd5f 301 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 46 182 1.2E-25 T 29-03-2018 SMALA_RS13490 3450773a2490858492427e27164dbd5f 301 Gene3D G3DSA:3.40.50.150 27 222 4.2E-41 T 29-03-2018 SMALA_RS19860 95569247a1a587ca138607eaecb0ea87 529 SMART SM00331 11 237 1.3E-39 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS19860 95569247a1a587ca138607eaecb0ea87 529 SMART SM00332 2 235 6.9E-29 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS19860 95569247a1a587ca138607eaecb0ea87 529 Pfam PF00481 Protein phosphatase 2C 22 229 1.0E-10 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS19860 95569247a1a587ca138607eaecb0ea87 529 SUPERFAMILY SSF81606 4 236 3.4E-66 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS19860 95569247a1a587ca138607eaecb0ea87 529 Gene3D G3DSA:3.60.40.10 5 237 7.4E-45 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS29955 69b562ee9c029a236aa529fc90f032d0 232 SUPERFAMILY SSF53335 61 215 2.86E-15 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS29955 69b562ee9c029a236aa529fc90f032d0 232 Gene3D G3DSA:3.40.50.150 5 221 2.0E-14 T 29-03-2018 SMALA_RS29955 69b562ee9c029a236aa529fc90f032d0 232 Pfam PF13489 Methyltransferase domain 61 170 1.4E-8 T 29-03-2018 SMALA_RS21910 7cc49e0ab1ee44346010ed385f1f9269 251 Gene3D G3DSA:3.40.50.720 1 237 2.9E-56 T 29-03-2018 SMALA_RS21910 7cc49e0ab1ee44346010ed385f1f9269 251 SUPERFAMILY SSF51735 2 238 5.72E-61 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS21910 7cc49e0ab1ee44346010ed385f1f9269 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 6.5E-23 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS21910 7cc49e0ab1ee44346010ed385f1f9269 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 6.5E-23 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS21910 7cc49e0ab1ee44346010ed385f1f9269 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 6.5E-23 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS21910 7cc49e0ab1ee44346010ed385f1f9269 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 168 6.5E-23 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS21910 7cc49e0ab1ee44346010ed385f1f9269 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 139 6.5E-23 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS21910 7cc49e0ab1ee44346010ed385f1f9269 251 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4 185 4.0E-4 T 29-03-2018 SMALA_RS21910 7cc49e0ab1ee44346010ed385f1f9269 251 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 136 164 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMALA_RS21910 7cc49e0ab1ee44346010ed385f1f9269 251 Pfam PF00106 short chain dehydrogenase 5 186 1.4E-49 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS38935 1b16af7c76cb896552a4d6bdcbe276bb 221 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 76 217 6.4E-18 T 29-03-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 SMALA_RS38935 1b16af7c76cb896552a4d6bdcbe276bb 221 SUPERFAMILY SSF48498 81 219 9.89E-26 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS38935 1b16af7c76cb896552a4d6bdcbe276bb 221 SUPERFAMILY SSF46689 8 71 1.45E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS38935 1b16af7c76cb896552a4d6bdcbe276bb 221 PRINTS PR00400 Tetracycline repressor protein signature 83 102 3.2E-11 T 29-03-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 SMALA_RS38935 1b16af7c76cb896552a4d6bdcbe276bb 221 PRINTS PR00400 Tetracycline repressor protein signature 31 54 3.2E-11 T 29-03-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 SMALA_RS38935 1b16af7c76cb896552a4d6bdcbe276bb 221 PRINTS PR00400 Tetracycline repressor protein signature 200 214 3.2E-11 T 29-03-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 SMALA_RS38935 1b16af7c76cb896552a4d6bdcbe276bb 221 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 63 3.7E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS38935 1b16af7c76cb896552a4d6bdcbe276bb 221 Gene3D G3DSA:1.10.357.10 90 221 1.9E-27 T 29-03-2018 SMALA_RS38935 1b16af7c76cb896552a4d6bdcbe276bb 221 Gene3D G3DSA:1.10.10.60 1 54 2.9E-16 T 29-03-2018 SMALA_RS38935 1b16af7c76cb896552a4d6bdcbe276bb 221 Gene3D G3DSA:1.10.10.60 55 89 3.8E-5 T 29-03-2018 SMALA_RS16595 8db9ae0bd5cb8f9b879ea17555c5f337 259 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 12 184 3.4E-4 T 29-03-2018 SMALA_RS16595 8db9ae0bd5cb8f9b879ea17555c5f337 259 Gene3D G3DSA:3.40.50.720 1 258 7.2E-74 T 29-03-2018 SMALA_RS16595 8db9ae0bd5cb8f9b879ea17555c5f337 259 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 150 178 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMALA_RS16595 8db9ae0bd5cb8f9b879ea17555c5f337 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 256 3.1E-62 T 29-03-2018 SMALA_RS16595 8db9ae0bd5cb8f9b879ea17555c5f337 259 SUPERFAMILY SSF51735 11 256 2.91E-80 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS16595 8db9ae0bd5cb8f9b879ea17555c5f337 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 143 151 3.3E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS16595 8db9ae0bd5cb8f9b879ea17555c5f337 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 163 182 3.3E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS16595 8db9ae0bd5cb8f9b879ea17555c5f337 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 90 101 3.3E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS16595 8db9ae0bd5cb8f9b879ea17555c5f337 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 182 4.7E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS16595 8db9ae0bd5cb8f9b879ea17555c5f337 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 137 153 4.7E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS16595 8db9ae0bd5cb8f9b879ea17555c5f337 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 239 4.7E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS16595 8db9ae0bd5cb8f9b879ea17555c5f337 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 4.7E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS16595 8db9ae0bd5cb8f9b879ea17555c5f337 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 90 101 4.7E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS16595 8db9ae0bd5cb8f9b879ea17555c5f337 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 184 201 4.7E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS14495 a6503ec13b3d76040a0e7f738ed01f46 259 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 16 128 5.4E-6 T 29-03-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal SMALA_RS16145 f309ec30ba7c7bf7039981a27d81d0c9 406 SUPERFAMILY SSF53901 283 404 3.84E-43 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS16145 f309ec30ba7c7bf7039981a27d81d0c9 406 PIRSF PIRSF000429 1 406 6.5E-131 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 SMALA_RS16145 f309ec30ba7c7bf7039981a27d81d0c9 406 SUPERFAMILY SSF53901 3 282 1.68E-66 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS16145 f309ec30ba7c7bf7039981a27d81d0c9 406 Gene3D G3DSA:3.40.47.10 278 402 2.3E-33 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS16145 f309ec30ba7c7bf7039981a27d81d0c9 406 Gene3D G3DSA:3.40.47.10 1 277 5.1E-53 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS16145 f309ec30ba7c7bf7039981a27d81d0c9 406 ProSitePatterns PS00737 Thiolases signature 2. 351 367 - T 29-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 SMALA_RS16145 f309ec30ba7c7bf7039981a27d81d0c9 406 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 403 4.0E-140 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 SMALA_RS16145 f309ec30ba7c7bf7039981a27d81d0c9 406 Pfam PF02803 Thiolase, C-terminal domain 283 404 5.1E-47 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 SMALA_RS16145 f309ec30ba7c7bf7039981a27d81d0c9 406 Pfam PF00108 Thiolase, N-terminal domain 5 274 1.5E-61 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 SMALA_RS25375 1a4957013ca382a6a7bf684bb09e159e 414 Pfam PF12704 MacB-like periplasmic core domain 47 210 3.9E-13 T 29-03-2018 IPR025857 MacB-like periplasmic core domain SMALA_RS25375 1a4957013ca382a6a7bf684bb09e159e 414 Pfam PF02687 FtsX-like permease family 319 407 1.1E-12 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 SMALA_RS32445 9a026639a5b1c948e83e20c9753a9394 400 Gene3D G3DSA:3.40.640.10 162 283 5.3E-41 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS32445 9a026639a5b1c948e83e20c9753a9394 400 PIRSF PIRSF000521 166 389 4.8E-31 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMALA_RS32445 9a026639a5b1c948e83e20c9753a9394 400 PIRSF PIRSF000521 22 125 1.5E-5 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMALA_RS32445 9a026639a5b1c948e83e20c9753a9394 400 PIRSF PIRSF000521 117 149 3.5 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMALA_RS32445 9a026639a5b1c948e83e20c9753a9394 400 Gene3D G3DSA:3.90.1150.10 2 159 5.4E-48 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS32445 9a026639a5b1c948e83e20c9753a9394 400 Gene3D G3DSA:3.90.1150.10 284 393 8.5E-28 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS32445 9a026639a5b1c948e83e20c9753a9394 400 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 214 251 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMALA_RS32445 9a026639a5b1c948e83e20c9753a9394 400 SUPERFAMILY SSF53383 14 387 7.79E-120 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS32445 9a026639a5b1c948e83e20c9753a9394 400 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 14 386 9.9E-141 T 29-03-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 SMALA_RS32445 9a026639a5b1c948e83e20c9753a9394 400 Pfam PF00202 Aminotransferase class-III 22 384 2.0E-108 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMALA_RS32445 9a026639a5b1c948e83e20c9753a9394 400 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 11 387 43.246 T 29-03-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 SMALA_RS06020 c5f30b66cc6f1c6c37ff27263e476376 124 Gene3D G3DSA:1.10.10.10 12 74 6.5E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS06020 c5f30b66cc6f1c6c37ff27263e476376 124 Pfam PF03965 Penicillinase repressor 12 119 1.1E-23 T 29-03-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 SMALA_RS06020 c5f30b66cc6f1c6c37ff27263e476376 124 SUPERFAMILY SSF46785 12 119 4.77E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS32325 c6f2159d34596dd77d4b3357d1007fcb 373 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 69 367 2.3E-89 T 29-03-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 SMALA_RS32325 c6f2159d34596dd77d4b3357d1007fcb 373 Pfam PF01409 tRNA synthetases class II core domain (F) 109 368 8.1E-103 T 29-03-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 SMALA_RS32325 c6f2159d34596dd77d4b3357d1007fcb 373 SUPERFAMILY SSF55681 109 370 4.66E-76 T 29-03-2018 SMALA_RS32325 c6f2159d34596dd77d4b3357d1007fcb 373 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 37 104 1.1E-16 T 29-03-2018 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 SMALA_RS32325 c6f2159d34596dd77d4b3357d1007fcb 373 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 25 369 46.097 T 29-03-2018 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 SMALA_RS32325 c6f2159d34596dd77d4b3357d1007fcb 373 SUPERFAMILY SSF46589 29 115 2.3E-14 T 29-03-2018 IPR010978 tRNA-binding arm GO:0000166 SMALA_RS32325 c6f2159d34596dd77d4b3357d1007fcb 373 Gene3D G3DSA:3.30.930.10 24 372 1.1E-81 T 29-03-2018 SMALA_RS10605 111ac4d05212cea04da6586300fc0622 431 Gene3D G3DSA:3.30.565.10 184 424 1.5E-24 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS10605 111ac4d05212cea04da6586300fc0622 431 Pfam PF07730 Histidine kinase 200 264 8.0E-19 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMALA_RS10605 111ac4d05212cea04da6586300fc0622 431 SMART SM00387 311 425 9.2E-5 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS10605 111ac4d05212cea04da6586300fc0622 431 SUPERFAMILY SSF55874 312 424 4.93E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS10605 111ac4d05212cea04da6586300fc0622 431 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 317 424 2.1E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS06075 bf1b2be162db377391a0fde637819413 347 Gene3D G3DSA:3.40.50.20 187 249 1.8E-13 T 29-03-2018 SMALA_RS06075 bf1b2be162db377391a0fde637819413 347 SMART SM00829 11 341 1.1E-5 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS06075 bf1b2be162db377391a0fde637819413 347 Gene3D G3DSA:3.90.180.10 250 345 0.0072 T 29-03-2018 SMALA_RS06075 bf1b2be162db377391a0fde637819413 347 Pfam PF00107 Zinc-binding dehydrogenase 186 307 1.3E-14 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMALA_RS06075 bf1b2be162db377391a0fde637819413 347 SUPERFAMILY SSF51735 149 311 1.23E-35 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS06075 bf1b2be162db377391a0fde637819413 347 Gene3D G3DSA:3.90.180.10 1 186 1.6E-49 T 29-03-2018 SMALA_RS06075 bf1b2be162db377391a0fde637819413 347 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 144 1.2E-26 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS06075 bf1b2be162db377391a0fde637819413 347 SUPERFAMILY SSF50129 10 172 5.2E-46 T 29-03-2018 IPR011032 GroES-like SMALA_RS06075 bf1b2be162db377391a0fde637819413 347 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 SMALA_RS35840 5b63a8dab74446caa40d32847af3686c 627 Gene3D G3DSA:3.20.20.240 48 486 1.1E-160 T 29-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMALA_RS35840 5b63a8dab74446caa40d32847af3686c 627 Gene3D G3DSA:3.40.50.280 491 627 7.3E-36 T 29-03-2018 SMALA_RS35840 5b63a8dab74446caa40d32847af3686c 627 Gene3D G3DSA:1.10.196.20 8 43 1.3E-14 T 29-03-2018 IPR024067 Methylmalonyl-CoA mutase small subunit, N-terminal KEGG: 00280+5.4.99.2|KEGG: 00630+5.4.99.2|KEGG: 00640+5.4.99.2|KEGG: 00720+5.4.99.2|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384|MetaCyc: PWY-7854 SMALA_RS35840 5b63a8dab74446caa40d32847af3686c 627 SUPERFAMILY SSF52242 500 622 2.75E-6 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 SMALA_RS35840 5b63a8dab74446caa40d32847af3686c 627 ProSitePatterns PS00544 Methylmalonyl-CoA mutase signature. 365 390 - T 29-03-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMALA_RS35840 5b63a8dab74446caa40d32847af3686c 627 SUPERFAMILY SSF51703 9 540 7.85E-155 T 29-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMALA_RS35840 5b63a8dab74446caa40d32847af3686c 627 Pfam PF01642 Methylmalonyl-CoA mutase 52 533 6.0E-138 T 29-03-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMALA_RS35840 5b63a8dab74446caa40d32847af3686c 627 TIGRFAM TIGR00642 mmCoA_mut_beta: methylmalonyl-CoA mutase, small subunit 9 627 4.1E-192 T 29-03-2018 IPR004608 Methylmalonyl-CoA mutase, beta chain GO:0004494|GO:0019652|GO:0031419 KEGG: 00280+5.4.99.2|KEGG: 00630+5.4.99.2|KEGG: 00640+5.4.99.2|KEGG: 00720+5.4.99.2|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384|MetaCyc: PWY-7854 SMALA_RS41525 5946f7acd2766fc1af68ece07012d76f 303 Gene3D G3DSA:3.40.800.10 3 290 4.7E-57 T 29-03-2018 SMALA_RS41525 5946f7acd2766fc1af68ece07012d76f 303 SUPERFAMILY SSF52768 5 288 8.1E-55 T 29-03-2018 SMALA_RS41525 5946f7acd2766fc1af68ece07012d76f 303 PIRSF PIRSF036979 2 291 4.4E-48 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 SMALA_RS41525 5946f7acd2766fc1af68ece07012d76f 303 PRINTS PR00116 Arginase signature 102 117 1.8E-8 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 SMALA_RS41525 5946f7acd2766fc1af68ece07012d76f 303 PRINTS PR00116 Arginase signature 217 246 1.8E-8 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 SMALA_RS41525 5946f7acd2766fc1af68ece07012d76f 303 Pfam PF00491 Arginase family 8 287 9.2E-54 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 SMALA_RS22385 5831c807b6c18f70667f3be4d9875ed4 54 ProSitePatterns PS00582 Ribosomal protein L33 signature. 22 41 - T 29-03-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS22385 5831c807b6c18f70667f3be4d9875ed4 54 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 6 54 19.785 T 29-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS22385 5831c807b6c18f70667f3be4d9875ed4 54 Pfam PF00471 Ribosomal protein L33 9 54 1.8E-23 T 29-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS22385 5831c807b6c18f70667f3be4d9875ed4 54 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 2 54 1.8E-22 T 29-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS22385 5831c807b6c18f70667f3be4d9875ed4 54 SUPERFAMILY SSF57829 4 54 7.32E-20 T 29-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 SMALA_RS37530 5f5d18a93f8ff206660012c73bf21c60 334 Gene3D G3DSA:3.40.50.720 137 310 2.9E-39 T 29-03-2018 SMALA_RS37530 5f5d18a93f8ff206660012c73bf21c60 334 Gene3D G3DSA:3.90.180.10 1 136 5.0E-36 T 29-03-2018 SMALA_RS37530 5f5d18a93f8ff206660012c73bf21c60 334 SUPERFAMILY SSF50129 1 142 6.76E-37 T 29-03-2018 IPR011032 GroES-like SMALA_RS37530 5f5d18a93f8ff206660012c73bf21c60 334 SUPERFAMILY SSF51735 114 273 2.21E-50 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS37530 5f5d18a93f8ff206660012c73bf21c60 334 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 142 163 - T 29-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 SMALA_RS37530 5f5d18a93f8ff206660012c73bf21c60 334 SMART SM00829 13 324 4.8E-42 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS37530 5f5d18a93f8ff206660012c73bf21c60 334 Pfam PF00107 Zinc-binding dehydrogenase 153 271 1.0E-31 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMALA_RS37530 5f5d18a93f8ff206660012c73bf21c60 334 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 93 5.4E-7 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS25890 d6b9d9b2928e94f86f640e09672c08a7 201 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 6 194 4.7E-44 T 29-03-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 SMALA_RS25890 d6b9d9b2928e94f86f640e09672c08a7 201 Pfam PF01914 MarC family integral membrane protein 6 196 5.2E-47 T 29-03-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 SMALA_RS01940 2f9fbe6022c5d44b7661652d83eceaa1 326 Gene3D G3DSA:3.40.190.10 32 123 9.9E-7 T 29-03-2018 SMALA_RS01940 2f9fbe6022c5d44b7661652d83eceaa1 326 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 4 24 5.4E-4 T 29-03-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal SMALA_RS01940 2f9fbe6022c5d44b7661652d83eceaa1 326 TIGRFAM TIGR01728 SsuA_fam: ABC transporter, substrate-binding protein, aliphatic sulfonates family 35 320 4.1E-62 T 29-03-2018 IPR010067 Aliphatic sulfonates-binding protein GO:0016020|GO:0042626 SMALA_RS01940 2f9fbe6022c5d44b7661652d83eceaa1 326 Pfam PF09084 NMT1/THI5 like 50 249 1.7E-15 T 29-03-2018 IPR015168 SsuA/THI5-like SMALA_RS01940 2f9fbe6022c5d44b7661652d83eceaa1 326 SUPERFAMILY SSF53850 35 250 2.24E-34 T 29-03-2018 SMALA_RS01940 2f9fbe6022c5d44b7661652d83eceaa1 326 Gene3D G3DSA:3.40.190.10 128 323 3.2E-24 T 29-03-2018 SMALA_RS32360 09f359cc3f7afe0df791150afa5d0600 176 ProSitePatterns PS00893 Nudix box signature. 74 95 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 SMALA_RS32360 09f359cc3f7afe0df791150afa5d0600 176 Pfam PF00293 NUDIX domain 40 152 5.1E-18 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SMALA_RS32360 09f359cc3f7afe0df791150afa5d0600 176 Gene3D G3DSA:3.90.79.10 1 174 7.7E-36 T 29-03-2018 SMALA_RS32360 09f359cc3f7afe0df791150afa5d0600 176 SUPERFAMILY SSF55811 3 173 2.17E-40 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMALA_RS10775 e660751a3c12b043905d8b7873913c73 234 Gene3D G3DSA:1.10.357.10 59 233 9.8E-38 T 29-03-2018 SMALA_RS10775 e660751a3c12b043905d8b7873913c73 234 SUPERFAMILY SSF48498 86 233 1.93E-29 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS10775 e660751a3c12b043905d8b7873913c73 234 Gene3D G3DSA:1.10.10.60 11 58 2.1E-15 T 29-03-2018 SMALA_RS10775 e660751a3c12b043905d8b7873913c73 234 SUPERFAMILY SSF46689 5 80 1.75E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS10775 e660751a3c12b043905d8b7873913c73 234 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 63 1.1E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS17575 9887a7bfafed0d3e53920d4e1232f4b5 142 Pfam PF00472 RF-1 domain 11 136 3.7E-22 T 29-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 SMALA_RS17575 9887a7bfafed0d3e53920d4e1232f4b5 142 SUPERFAMILY SSF75620 11 101 1.69E-11 T 29-03-2018 SMALA_RS17575 9887a7bfafed0d3e53920d4e1232f4b5 142 Gene3D G3DSA:3.30.160.20 6 141 5.4E-34 T 29-03-2018 SMALA_RS16605 334a87f2f00e21507629e6d1dc38bedc 170 TIGRFAM TIGR01313 therm_gnt_kin: carbohydrate kinase, thermoresistant glucokinase family 7 161 2.1E-56 T 29-03-2018 IPR006001 Carbohydrate kinase, thermoresistant glucokinase GO:0005975|GO:0016301 KEGG: 00030+2.7.1.12|MetaCyc: PWY-5530 SMALA_RS16605 334a87f2f00e21507629e6d1dc38bedc 170 SUPERFAMILY SSF52540 1 165 2.03E-24 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS16605 334a87f2f00e21507629e6d1dc38bedc 170 Pfam PF01202 Shikimate kinase 13 120 2.1E-11 T 29-03-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 SMALA_RS16605 334a87f2f00e21507629e6d1dc38bedc 170 Gene3D G3DSA:3.40.50.300 3 170 4.2E-28 T 29-03-2018 SMALA_RS12210 61da9762355d17230e0d73f2d6594e2d 263 Gene3D G3DSA:2.60.120.200 36 263 3.1E-67 T 29-03-2018 SMALA_RS12210 61da9762355d17230e0d73f2d6594e2d 263 Pfam PF08787 Alginate lyase 45 262 3.7E-58 T 29-03-2018 IPR014895 Alginate lyase 2 SMALA_RS12210 61da9762355d17230e0d73f2d6594e2d 263 SUPERFAMILY SSF49899 45 262 7.12E-58 T 29-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain SMALA_RS16825 25300d64e538d81dbad2b058aed72b01 247 Gene3D G3DSA:3.40.1000.10 109 239 7.0E-16 T 29-03-2018 SMALA_RS15400 4249d5060426103f535ff289aa37b765 388 SUPERFAMILY SSF69618 20 281 2.88E-57 T 29-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMALA_RS15400 4249d5060426103f535ff289aa37b765 388 Gene3D G3DSA:1.10.10.10 284 382 1.4E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS15400 4249d5060426103f535ff289aa37b765 388 Gene3D G3DSA:3.40.50.10090 52 178 4.7E-21 T 29-03-2018 SMALA_RS15400 4249d5060426103f535ff289aa37b765 388 SMART SM00862 305 375 1.9E-13 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS15400 4249d5060426103f535ff289aa37b765 388 Gene3D G3DSA:3.40.50.10090 179 280 5.8E-15 T 29-03-2018 SMALA_RS15400 4249d5060426103f535ff289aa37b765 388 Pfam PF00486 Transcriptional regulatory protein, C terminal 311 375 1.3E-12 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS15400 4249d5060426103f535ff289aa37b765 388 SUPERFAMILY SSF46894 290 375 1.47E-13 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS15400 4249d5060426103f535ff289aa37b765 388 Pfam PF02602 Uroporphyrinogen-III synthase HemD 32 274 3.4E-43 T 29-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMALA_RS01345 386853b6ed8427aa4006111447de150b 399 SUPERFAMILY SSF49998 51 393 1.01E-59 T 29-03-2018 IPR015798 Copper amine oxidase, C-terminal GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 SMALA_RS01345 386853b6ed8427aa4006111447de150b 399 Pfam PF01179 Copper amine oxidase, enzyme domain 54 391 7.7E-44 T 29-03-2018 IPR015798 Copper amine oxidase, C-terminal GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 SMALA_RS01345 386853b6ed8427aa4006111447de150b 399 Gene3D G3DSA:2.70.98.20 44 398 1.3E-62 T 29-03-2018 IPR015798 Copper amine oxidase, C-terminal GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 SMALA_RS40350 4ba286d89f292898b68ef98f81652288 230 SMART SM00866 83 222 1.7E-29 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMALA_RS40350 4ba286d89f292898b68ef98f81652288 230 SUPERFAMILY SSF64288 51 221 2.36E-44 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMALA_RS40350 4ba286d89f292898b68ef98f81652288 230 SUPERFAMILY SSF46785 2 65 2.62E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS40350 4ba286d89f292898b68ef98f81652288 230 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 35 51 1.9E-9 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS40350 4ba286d89f292898b68ef98f81652288 230 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 21 35 1.9E-9 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS40350 4ba286d89f292898b68ef98f81652288 230 Pfam PF07702 UTRA domain 85 217 3.3E-34 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMALA_RS40350 4ba286d89f292898b68ef98f81652288 230 SMART SM00345 2 61 1.2E-21 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS40350 4ba286d89f292898b68ef98f81652288 230 Gene3D G3DSA:3.40.1410.10 66 221 4.2E-41 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMALA_RS40350 4ba286d89f292898b68ef98f81652288 230 Pfam PF00392 Bacterial regulatory proteins, gntR family 2 61 1.2E-20 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS40350 4ba286d89f292898b68ef98f81652288 230 Gene3D G3DSA:1.10.10.10 1 63 3.8E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS26050 00fca0f672f712eaa8878ae855fa8fc4 379 Pfam PF00899 ThiF family 122 356 3.2E-16 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 SMALA_RS26050 00fca0f672f712eaa8878ae855fa8fc4 379 SUPERFAMILY SSF69572 122 354 3.66E-12 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 SMALA_RS26050 00fca0f672f712eaa8878ae855fa8fc4 379 Gene3D G3DSA:3.40.50.720 114 360 6.6E-27 T 29-03-2018 SMALA_RS32525 6e98b2f544d6e40cb1e2325b33c4291c 224 Gene3D G3DSA:3.40.1130.10 6 224 4.8E-53 T 29-03-2018 SMALA_RS32525 6e98b2f544d6e40cb1e2325b33c4291c 224 SUPERFAMILY SSF69593 5 221 7.45E-51 T 29-03-2018 SMALA_RS32525 6e98b2f544d6e40cb1e2325b33c4291c 224 Pfam PF01553 Acyltransferase 21 151 6.9E-22 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SMALA_RS32525 6e98b2f544d6e40cb1e2325b33c4291c 224 SMART SM00563 35 154 7.8E-35 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SMALA_RS37330 f48cbd14216f65a438d534c1cd8bd4d4 251 Gene3D G3DSA:3.90.226.10 3 242 2.2E-49 T 29-03-2018 SMALA_RS37330 f48cbd14216f65a438d534c1cd8bd4d4 251 SUPERFAMILY SSF52096 8 228 1.42E-54 T 29-03-2018 IPR029045 ClpP/crotonase-like domain SMALA_RS37330 f48cbd14216f65a438d534c1cd8bd4d4 251 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 209 1.6E-38 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 SMALA_RS38915 6f5cc9e8bee0afd6ab19c7ca6139c0c8 476 Pfam PF00474 Sodium:solute symporter family 28 402 2.4E-23 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 SMALA_RS28050 42a7a6c3b88898874874cf4318ec9620 1460 SUPERFAMILY SSF75553 498 570 1.1E-10 T 29-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 SMALA_RS28050 42a7a6c3b88898874874cf4318ec9620 1460 SMART SM00968 512 894 1.3E-19 T 29-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 SMALA_RS28050 42a7a6c3b88898874874cf4318ec9620 1460 Pfam PF06470 SMC proteins Flexible Hinge Domain 512 571 5.2E-11 T 29-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 SMALA_RS28050 42a7a6c3b88898874874cf4318ec9620 1460 Gene3D G3DSA:1.20.5.170 411 493 0.0022 T 29-03-2018 SMALA_RS28050 42a7a6c3b88898874874cf4318ec9620 1460 Gene3D G3DSA:1.20.5.170 325 410 0.0046 T 29-03-2018 SMALA_RS28050 42a7a6c3b88898874874cf4318ec9620 1460 Gene3D G3DSA:1.20.120.330 920 1056 0.04 T 29-03-2018 SMALA_RS28050 42a7a6c3b88898874874cf4318ec9620 1460 Gene3D G3DSA:3.40.50.300 2 209 6.1E-37 T 29-03-2018 SMALA_RS28050 42a7a6c3b88898874874cf4318ec9620 1460 Gene3D G3DSA:3.40.50.300 1235 1460 8.0E-32 T 29-03-2018 SMALA_RS28050 42a7a6c3b88898874874cf4318ec9620 1460 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 1460 22.564 T 29-03-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 SMALA_RS28050 42a7a6c3b88898874874cf4318ec9620 1460 SUPERFAMILY SSF52540 2 210 1.2E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS28050 42a7a6c3b88898874874cf4318ec9620 1460 SUPERFAMILY SSF52540 1345 1452 1.2E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS28050 42a7a6c3b88898874874cf4318ec9620 1460 Gene3D G3DSA:1.20.5.340 1066 1200 0.048 T 29-03-2018 SMALA_RS28050 42a7a6c3b88898874874cf4318ec9620 1460 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 1452 1.7E-71 T 29-03-2018 IPR003395 RecF/RecN/SMC, N-terminal SMALA_RS28050 42a7a6c3b88898874874cf4318ec9620 1460 PIRSF PIRSF005719 1 591 8.9E-137 T 29-03-2018 IPR024704 Structural maintenance of chromosomes protein SMALA_RS28050 42a7a6c3b88898874874cf4318ec9620 1460 PIRSF PIRSF005719 834 1460 1.6E-118 T 29-03-2018 IPR024704 Structural maintenance of chromosomes protein SMALA_RS28050 42a7a6c3b88898874874cf4318ec9620 1460 SUPERFAMILY SSF75553 856 939 1.96E-8 T 29-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 SMALA_RS10440 4f68ea5a7391bfc993d30fbe46407e3f 313 Gene3D G3DSA:3.30.420.40 116 313 4.5E-62 T 29-03-2018 SMALA_RS10440 4f68ea5a7391bfc993d30fbe46407e3f 313 ProSitePatterns PS01125 ROK family signature. 130 157 - T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 SMALA_RS10440 4f68ea5a7391bfc993d30fbe46407e3f 313 Pfam PF00480 ROK family 4 312 1.2E-101 T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 SMALA_RS10440 4f68ea5a7391bfc993d30fbe46407e3f 313 Gene3D G3DSA:3.30.420.40 1 115 1.2E-34 T 29-03-2018 SMALA_RS10440 4f68ea5a7391bfc993d30fbe46407e3f 313 SUPERFAMILY SSF53067 2 312 8.98E-70 T 29-03-2018 SMALA_RS10440 4f68ea5a7391bfc993d30fbe46407e3f 313 TIGRFAM TIGR00744 ROK_glcA_fam: ROK family protein (putative glucokinase) 5 311 2.3E-130 T 29-03-2018 IPR004654 Glucokinase ROK GO:0004340|GO:0005737|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 SMALA_RS06750 872f844561878ff9b54149efcc50c62d 249 Gene3D G3DSA:3.40.50.10140 1 147 3.5E-11 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 SMALA_RS06750 872f844561878ff9b54149efcc50c62d 249 SUPERFAMILY SSF52200 4 100 4.19E-6 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 SMALA_RS06750 872f844561878ff9b54149efcc50c62d 249 Pfam PF13676 TIR domain 4 122 1.7E-12 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 SMALA_RS28820 800c65439d3ac02d558e3a321d156885 203 Hamap MF_01114 Regulatory protein RecX [recX]. 33 189 14.927 T 29-03-2018 IPR003783 Regulatory protein RecX GO:0006282 SMALA_RS28820 800c65439d3ac02d558e3a321d156885 203 Gene3D G3DSA:1.10.10.10 139 192 8.3E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS28820 800c65439d3ac02d558e3a321d156885 203 Gene3D G3DSA:1.10.10.10 31 87 2.3E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS28820 800c65439d3ac02d558e3a321d156885 203 Gene3D G3DSA:1.10.10.10 88 133 4.7E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS28820 800c65439d3ac02d558e3a321d156885 203 Pfam PF02631 RecX family 64 184 1.9E-26 T 29-03-2018 IPR003783 Regulatory protein RecX GO:0006282 SMALA_RS03480 7cced0380dab5b683f9abb7b54395df9 131 Gene3D G3DSA:1.10.10.10 12 116 3.3E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS03480 7cced0380dab5b683f9abb7b54395df9 131 Pfam PF05331 Protein of unknown function (DUF742) 15 131 3.4E-36 T 29-03-2018 IPR007995 Protein of unknown function DUF742 SMALA_RS24835 094df91176e26dd3428a2b99371a6b13 813 SMART SM00331 469 685 1.6E-36 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS24835 094df91176e26dd3428a2b99371a6b13 813 Pfam PF13581 Histidine kinase-like ATPase domain 704 792 4.9E-9 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS24835 094df91176e26dd3428a2b99371a6b13 813 SUPERFAMILY SSF81606 483 686 1.83E-8 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS24835 094df91176e26dd3428a2b99371a6b13 813 SUPERFAMILY SSF55874 724 809 2.21E-5 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS24835 094df91176e26dd3428a2b99371a6b13 813 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 495 685 6.4E-53 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS24835 094df91176e26dd3428a2b99371a6b13 813 SUPERFAMILY SSF55781 392 455 2.01E-7 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS24835 094df91176e26dd3428a2b99371a6b13 813 Gene3D G3DSA:3.60.40.10 442 688 3.3E-44 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS24835 094df91176e26dd3428a2b99371a6b13 813 Gene3D G3DSA:3.30.450.40 232 441 3.2E-20 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS24835 094df91176e26dd3428a2b99371a6b13 813 Gene3D G3DSA:3.30.565.10 690 813 3.6E-14 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS36285 7ae46a30076029b043c055ae0b4b4b9e 157 PIRSF PIRSF001399 8 154 2.5E-60 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SMALA_RS36285 7ae46a30076029b043c055ae0b4b4b9e 157 Pfam PF01220 Dehydroquinase class II 12 148 9.7E-60 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SMALA_RS36285 7ae46a30076029b043c055ae0b4b4b9e 157 ProSitePatterns PS01029 Dehydroquinase class II signature. 15 32 - T 29-03-2018 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SMALA_RS36285 7ae46a30076029b043c055ae0b4b4b9e 157 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 12 149 7.0E-57 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SMALA_RS36285 7ae46a30076029b043c055ae0b4b4b9e 157 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 157 68.892 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SMALA_RS36285 7ae46a30076029b043c055ae0b4b4b9e 157 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 12 141 1.0E-47 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SMALA_RS36285 7ae46a30076029b043c055ae0b4b4b9e 157 Gene3D G3DSA:3.40.50.9100 7 154 8.2E-64 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SMALA_RS36285 7ae46a30076029b043c055ae0b4b4b9e 157 SUPERFAMILY SSF52304 9 149 3.92E-60 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SMALA_RS02415 499c172a908f3f11d8b3bb50f808d4fb 248 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 9 228 1.1E-25 T 29-03-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMALA_RS02415 499c172a908f3f11d8b3bb50f808d4fb 248 SUPERFAMILY SSF54292 1 115 1.07E-21 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SMALA_RS02415 499c172a908f3f11d8b3bb50f808d4fb 248 Pfam PF12838 4Fe-4S dicluster domain 158 227 1.5E-10 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain SMALA_RS02415 499c172a908f3f11d8b3bb50f808d4fb 248 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 4 119 2.1E-24 T 29-03-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMALA_RS02415 499c172a908f3f11d8b3bb50f808d4fb 248 SUPERFAMILY SSF46548 118 241 4.01E-25 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 SMALA_RS02415 499c172a908f3f11d8b3bb50f808d4fb 248 Gene3D G3DSA:3.10.20.30 1 115 1.6E-26 T 29-03-2018 IPR012675 Beta-grasp domain SMALA_RS02415 499c172a908f3f11d8b3bb50f808d4fb 248 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 158 169 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site SMALA_RS02415 499c172a908f3f11d8b3bb50f808d4fb 248 Gene3D G3DSA:1.10.1060.10 116 247 5.9E-17 T 29-03-2018 SMALA_RS02415 499c172a908f3f11d8b3bb50f808d4fb 248 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 58 66 - T 29-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 SMALA_RS16335 bb454d7720bd5ed36581447c41a4e3d3 293 Pfam PF02237 Biotin protein ligase C terminal domain 238 285 2.4E-10 T 29-03-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780 SMALA_RS16335 bb454d7720bd5ed36581447c41a4e3d3 293 Pfam PF03099 Biotin/lipoate A/B protein ligase family 50 172 1.6E-10 T 29-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 SMALA_RS16335 bb454d7720bd5ed36581447c41a4e3d3 293 Gene3D G3DSA:3.30.930.10 10 237 3.3E-61 T 29-03-2018 SMALA_RS16335 bb454d7720bd5ed36581447c41a4e3d3 293 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 43 285 1.5E-38 T 29-03-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780 SMALA_RS16335 bb454d7720bd5ed36581447c41a4e3d3 293 SUPERFAMILY SSF55681 36 222 4.57E-43 T 29-03-2018 SMALA_RS16335 bb454d7720bd5ed36581447c41a4e3d3 293 Gene3D G3DSA:2.30.30.100 238 287 4.5E-16 T 29-03-2018 SMALA_RS03895 b1d22e6a66decd044d7536949d48903c 281 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 44 62 3.3E-9 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMALA_RS03895 b1d22e6a66decd044d7536949d48903c 281 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 30 44 3.3E-9 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMALA_RS03895 b1d22e6a66decd044d7536949d48903c 281 SMART SM00420 12 64 3.1E-17 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMALA_RS03895 b1d22e6a66decd044d7536949d48903c 281 SMART SM01134 80 253 1.2E-55 T 29-03-2018 SMALA_RS03895 b1d22e6a66decd044d7536949d48903c 281 Gene3D G3DSA:1.10.10.10 3 71 1.3E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS03895 b1d22e6a66decd044d7536949d48903c 281 SUPERFAMILY SSF100950 172 252 3.35E-30 T 29-03-2018 SMALA_RS03895 b1d22e6a66decd044d7536949d48903c 281 SUPERFAMILY SSF100950 84 139 3.35E-30 T 29-03-2018 SMALA_RS03895 b1d22e6a66decd044d7536949d48903c 281 Gene3D G3DSA:3.40.50.1360 73 260 2.1E-40 T 29-03-2018 SMALA_RS03895 b1d22e6a66decd044d7536949d48903c 281 Pfam PF00455 DeoR C terminal sensor domain 84 251 6.0E-49 T 29-03-2018 IPR014036 DeoR C-terminal sensor domain SMALA_RS03895 b1d22e6a66decd044d7536949d48903c 281 Pfam PF08220 DeoR-like helix-turn-helix domain 12 64 2.2E-16 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMALA_RS03895 b1d22e6a66decd044d7536949d48903c 281 ProSitePatterns PS00894 DeoR-type HTH domain signature. 12 46 - T 29-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 SMALA_RS03895 b1d22e6a66decd044d7536949d48903c 281 SUPERFAMILY SSF46785 10 72 3.81E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS28620 96b2d943326e5c08222829a49b3516d8 823 Pfam PF13360 PQQ-like domain 466 646 3.3E-12 T 29-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat SMALA_RS28620 96b2d943326e5c08222829a49b3516d8 823 Pfam PF13360 PQQ-like domain 677 820 3.7E-13 T 29-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat SMALA_RS28620 96b2d943326e5c08222829a49b3516d8 823 SUPERFAMILY SSF50998 465 650 2.22E-13 T 29-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily SMALA_RS28620 96b2d943326e5c08222829a49b3516d8 823 Gene3D G3DSA:1.10.510.10 31 264 6.1E-15 T 29-03-2018 SMALA_RS28620 96b2d943326e5c08222829a49b3516d8 823 SMART SM00564 480 511 4.5 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMALA_RS28620 96b2d943326e5c08222829a49b3516d8 823 SMART SM00564 706 737 0.74 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMALA_RS28620 96b2d943326e5c08222829a49b3516d8 823 SMART SM00564 747 785 140.0 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMALA_RS28620 96b2d943326e5c08222829a49b3516d8 823 SMART SM00220 15 259 4.9E-4 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMALA_RS28620 96b2d943326e5c08222829a49b3516d8 823 SUPERFAMILY SSF50998 635 656 3.14E-13 T 29-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily SMALA_RS28620 96b2d943326e5c08222829a49b3516d8 823 SUPERFAMILY SSF50998 702 820 3.14E-13 T 29-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily SMALA_RS28620 96b2d943326e5c08222829a49b3516d8 823 Gene3D G3DSA:2.140.10.10 678 823 1.5E-13 T 29-03-2018 SMALA_RS28620 96b2d943326e5c08222829a49b3516d8 823 SUPERFAMILY SSF56112 83 256 1.76E-17 T 29-03-2018 IPR011009 Protein kinase-like domain SMALA_RS28620 96b2d943326e5c08222829a49b3516d8 823 Gene3D G3DSA:2.140.10.10 430 673 6.4E-17 T 29-03-2018 SMALA_RS42115 60dddcc5e8079cb27bf062bc9a1a9608 360 Gene3D G3DSA:3.50.50.60 3 64 1.2E-7 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS42115 60dddcc5e8079cb27bf062bc9a1a9608 360 Pfam PF01266 FAD dependent oxidoreductase 9 355 4.4E-43 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 SMALA_RS42115 60dddcc5e8079cb27bf062bc9a1a9608 360 Gene3D G3DSA:3.30.9.10 65 317 7.2E-23 T 29-03-2018 SMALA_RS42115 60dddcc5e8079cb27bf062bc9a1a9608 360 SUPERFAMILY SSF51905 317 357 1.9E-43 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS42115 60dddcc5e8079cb27bf062bc9a1a9608 360 SUPERFAMILY SSF51905 8 222 1.9E-43 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS30880 6038e9a9e1363a6e3d699c4dec352584 326 PIRSF PIRSF015582 2 324 1.5E-89 T 29-03-2018 IPR011206 Citrate lyase beta subunit-like SMALA_RS30880 6038e9a9e1363a6e3d699c4dec352584 326 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 17 247 1.4E-46 T 29-03-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 SMALA_RS30880 6038e9a9e1363a6e3d699c4dec352584 326 SUPERFAMILY SSF51621 13 258 1.39E-66 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SMALA_RS30880 6038e9a9e1363a6e3d699c4dec352584 326 Gene3D G3DSA:3.20.20.60 3 259 8.3E-62 T 29-03-2018 SMALA_RS20815 2bffa7488f0e9ec0d01ce331b966d3ee 427 Gene3D G3DSA:3.40.440.10 149 264 2.2E-29 T 29-03-2018 SMALA_RS20815 2bffa7488f0e9ec0d01ce331b966d3ee 427 Gene3D G3DSA:3.40.440.10 2 148 4.0E-49 T 29-03-2018 SMALA_RS20815 2bffa7488f0e9ec0d01ce331b966d3ee 427 SMART SM00788 3 422 1.2E-289 T 29-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 SMALA_RS20815 2bffa7488f0e9ec0d01ce331b966d3ee 427 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 5 424 2.6E-170 T 29-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 SMALA_RS20815 2bffa7488f0e9ec0d01ce331b966d3ee 427 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 131 142 - T 29-03-2018 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 SMALA_RS20815 2bffa7488f0e9ec0d01ce331b966d3ee 427 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 29-03-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 SMALA_RS20815 2bffa7488f0e9ec0d01ce331b966d3ee 427 SUPERFAMILY SSF52540 3 425 6.27E-175 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS20815 2bffa7488f0e9ec0d01ce331b966d3ee 427 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 427 202.438 T 29-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 SMALA_RS20815 2bffa7488f0e9ec0d01ce331b966d3ee 427 Gene3D G3DSA:3.90.170.10 265 427 9.5E-70 T 29-03-2018 SMALA_RS20815 2bffa7488f0e9ec0d01ce331b966d3ee 427 Pfam PF00709 Adenylosuccinate synthetase 5 421 9.4E-181 T 29-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 SMALA_RS15075 1b1a9bf7e0e1616d7110efac73080361 194 SUPERFAMILY SSF52499 2 188 2.75E-48 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SMALA_RS15075 1b1a9bf7e0e1616d7110efac73080361 194 Gene3D G3DSA:3.40.50.850 1 190 4.7E-58 T 29-03-2018 SMALA_RS15075 1b1a9bf7e0e1616d7110efac73080361 194 Pfam PF00857 Isochorismatase family 4 188 3.7E-32 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SMALA_RS07285 a2a994296323c96224da9a3c2f1d1deb 416 Gene3D G3DSA:3.10.580.10 347 413 0.011 T 29-03-2018 SMALA_RS07285 a2a994296323c96224da9a3c2f1d1deb 416 SUPERFAMILY SSF54631 289 405 1.39E-10 T 29-03-2018 SMALA_RS07285 a2a994296323c96224da9a3c2f1d1deb 416 Pfam PF02163 Peptidase family M50 168 209 5.3E-7 T 29-03-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889|Reactome: R-MMU-8963889 SMALA_RS07285 a2a994296323c96224da9a3c2f1d1deb 416 PIRSF PIRSF006404 32 413 1.5E-103 T 29-03-2018 IPR016483 Uncharacterised conserved protein UCP006404, peptidase M50/CBS SMALA_RS07285 a2a994296323c96224da9a3c2f1d1deb 416 Gene3D G3DSA:3.10.580.10 154 338 3.5E-6 T 29-03-2018 SMALA_RS26140 e1103eefba063ad69f4c5ac142bb1f33 130 SMART SM00116 10 58 0.0036 T 29-03-2018 IPR000644 CBS domain SMALA_RS26140 e1103eefba063ad69f4c5ac142bb1f33 130 SMART SM00116 75 122 9.6E-8 T 29-03-2018 IPR000644 CBS domain SMALA_RS26140 e1103eefba063ad69f4c5ac142bb1f33 130 Gene3D G3DSA:3.10.580.10 1 125 1.1E-25 T 29-03-2018 SMALA_RS26140 e1103eefba063ad69f4c5ac142bb1f33 130 SUPERFAMILY SSF54631 1 122 8.21E-30 T 29-03-2018 SMALA_RS26140 e1103eefba063ad69f4c5ac142bb1f33 130 Pfam PF00571 CBS domain 73 120 4.9E-10 T 29-03-2018 IPR000644 CBS domain SMALA_RS26140 e1103eefba063ad69f4c5ac142bb1f33 130 Pfam PF00571 CBS domain 3 57 6.0E-8 T 29-03-2018 IPR000644 CBS domain SMALA_RS28015 2822f7666e71b814d35cffb2bb24cdf5 57 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 2 55 18.926 T 29-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS28015 2822f7666e71b814d35cffb2bb24cdf5 57 SUPERFAMILY SSF57829 2 57 4.88E-21 T 29-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 SMALA_RS28015 2822f7666e71b814d35cffb2bb24cdf5 57 Pfam PF01783 Ribosomal L32p protein family 2 56 3.1E-25 T 29-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS28015 2822f7666e71b814d35cffb2bb24cdf5 57 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 56 3.4E-26 T 29-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS07645 08fca4a8483ea337d3341181202a18bc 907 Pfam PF03704 Bacterial transcriptional activator domain 758 896 3.0E-14 T 29-03-2018 IPR005158 Bacterial transcriptional activator domain SMALA_RS07645 08fca4a8483ea337d3341181202a18bc 907 SUPERFAMILY SSF48452 761 899 2.61E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS07645 08fca4a8483ea337d3341181202a18bc 907 Pfam PF01476 LysM domain 186 241 2.9E-8 T 29-03-2018 IPR018392 LysM domain SMALA_RS07645 08fca4a8483ea337d3341181202a18bc 907 SMART SM00257 185 241 0.0095 T 29-03-2018 IPR018392 LysM domain SMALA_RS07645 08fca4a8483ea337d3341181202a18bc 907 Gene3D G3DSA:1.25.40.10 778 880 1.3E-4 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS07645 08fca4a8483ea337d3341181202a18bc 907 SMART SM01043 758 901 6.4E-19 T 29-03-2018 IPR005158 Bacterial transcriptional activator domain SMALA_RS07645 08fca4a8483ea337d3341181202a18bc 907 Gene3D G3DSA:3.10.350.10 179 246 2.4E-15 T 29-03-2018 SMALA_RS07645 08fca4a8483ea337d3341181202a18bc 907 Gene3D G3DSA:1.10.10.10 648 752 1.1E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS36570 6cfab38321150141770cc1120db0ea9d 896 Gene3D G3DSA:3.30.565.10 750 881 1.1E-10 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS36570 6cfab38321150141770cc1120db0ea9d 896 SUPERFAMILY SSF103190 39 169 4.71E-27 T 29-03-2018 IPR029151 Periplasmic sensor domain-like SMALA_RS36570 6cfab38321150141770cc1120db0ea9d 896 SMART SM00331 524 746 1.5E-34 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS36570 6cfab38321150141770cc1120db0ea9d 896 Gene3D G3DSA:3.30.450.20 33 170 7.6E-21 T 29-03-2018 SMALA_RS36570 6cfab38321150141770cc1120db0ea9d 896 SUPERFAMILY SSF81606 539 745 2.88E-8 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS36570 6cfab38321150141770cc1120db0ea9d 896 Gene3D G3DSA:3.30.450.20 205 328 9.3E-12 T 29-03-2018 SMALA_RS36570 6cfab38321150141770cc1120db0ea9d 896 Pfam PF13185 GAF domain 418 497 4.4E-8 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS36570 6cfab38321150141770cc1120db0ea9d 896 SUPERFAMILY SSF55781 415 507 3.27E-14 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS36570 6cfab38321150141770cc1120db0ea9d 896 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 551 746 7.0E-48 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS36570 6cfab38321150141770cc1120db0ea9d 896 SMART SM00091 213 278 0.0023 T 29-03-2018 IPR000014 PAS domain SMALA_RS36570 6cfab38321150141770cc1120db0ea9d 896 Pfam PF17203 Single cache domain 3 36 169 2.6E-22 T 29-03-2018 IPR033463 Single cache domain 3 SMALA_RS36570 6cfab38321150141770cc1120db0ea9d 896 Pfam PF13581 Histidine kinase-like ATPase domain 759 864 7.6E-7 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS36570 6cfab38321150141770cc1120db0ea9d 896 Gene3D G3DSA:3.30.450.40 335 502 3.1E-34 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS36570 6cfab38321150141770cc1120db0ea9d 896 SUPERFAMILY SSF55785 209 310 3.4E-7 T 29-03-2018 IPR000014 PAS domain SMALA_RS36570 6cfab38321150141770cc1120db0ea9d 896 Gene3D G3DSA:3.60.40.10 503 749 1.7E-42 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS36570 6cfab38321150141770cc1120db0ea9d 896 SMART SM00065 339 506 6.7E-4 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS22070 61bf6f8dd27626d1d9dfd872de9278db 399 TIGRFAM TIGR00423 TIGR00423: radical SAM domain protein, CofH subfamily 57 360 3.1E-103 T 29-03-2018 IPR020050 FO synthase, subunit 2 GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 SMALA_RS22070 61bf6f8dd27626d1d9dfd872de9278db 399 Hamap MF_00992 Cyclic dehypoxanthine futalosine synthase [mqnC]. 17 363 50.419 T 29-03-2018 IPR022431 Cyclic dehypoxanthine futalosine synthase GO:0009234 KEGG: 00130+1.21.98.1|MetaCyc: PWY-7371|MetaCyc: PWY-7374 SMALA_RS22070 61bf6f8dd27626d1d9dfd872de9278db 399 Gene3D G3DSA:3.20.20.70 1 362 1.1E-51 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS22070 61bf6f8dd27626d1d9dfd872de9278db 399 TIGRFAM TIGR03699 menaquin_MqnC: dehypoxanthine futalosine cyclase 19 360 6.5E-138 T 29-03-2018 IPR022431 Cyclic dehypoxanthine futalosine synthase GO:0009234 KEGG: 00130+1.21.98.1|MetaCyc: PWY-7371|MetaCyc: PWY-7374 SMALA_RS22070 61bf6f8dd27626d1d9dfd872de9278db 399 Pfam PF04055 Radical SAM superfamily 65 238 2.7E-16 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 SMALA_RS22070 61bf6f8dd27626d1d9dfd872de9278db 399 SUPERFAMILY SSF102114 18 352 2.09E-51 T 29-03-2018 SMALA_RS22070 61bf6f8dd27626d1d9dfd872de9278db 399 PIRSF PIRSF004762 1 372 3.9E-107 T 29-03-2018 SMALA_RS33355 b43bcb7e015c8262cad55ffd4b0d5c62 572 Gene3D G3DSA:1.10.10.60 479 541 1.3E-7 T 29-03-2018 SMALA_RS33355 b43bcb7e015c8262cad55ffd4b0d5c62 572 Gene3D G3DSA:3.30.450.40 43 187 0.0041 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS33355 b43bcb7e015c8262cad55ffd4b0d5c62 572 Pfam PF13556 PucR C-terminal helix-turn-helix domain 505 563 6.0E-22 T 29-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain SMALA_RS33355 b43bcb7e015c8262cad55ffd4b0d5c62 572 Gene3D G3DSA:3.30.450.40 188 326 0.34 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS02155 496a7a3310905654a5fff57c9c7b6e3c 309 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 187 305 7.1E-6 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS02155 496a7a3310905654a5fff57c9c7b6e3c 309 Pfam PF07730 Histidine kinase 81 148 2.3E-16 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMALA_RS02155 496a7a3310905654a5fff57c9c7b6e3c 309 SUPERFAMILY SSF55874 163 305 1.96E-12 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS02155 496a7a3310905654a5fff57c9c7b6e3c 309 Gene3D G3DSA:3.30.565.10 45 307 1.7E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS17740 ef603dd7cff06cf040dfdce29364de0a 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 1.1E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS17740 ef603dd7cff06cf040dfdce29364de0a 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 1.1E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS17740 ef603dd7cff06cf040dfdce29364de0a 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 1.1E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS17740 ef603dd7cff06cf040dfdce29364de0a 255 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMALA_RS17740 ef603dd7cff06cf040dfdce29364de0a 255 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 13 203 0.0038 T 29-03-2018 SMALA_RS17740 ef603dd7cff06cf040dfdce29364de0a 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 19 252 4.5E-61 T 29-03-2018 SMALA_RS17740 ef603dd7cff06cf040dfdce29364de0a 255 Gene3D G3DSA:3.40.50.720 6 51 2.3E-10 T 29-03-2018 SMALA_RS17740 ef603dd7cff06cf040dfdce29364de0a 255 Gene3D G3DSA:3.40.50.720 52 255 6.6E-63 T 29-03-2018 SMALA_RS17740 ef603dd7cff06cf040dfdce29364de0a 255 SUPERFAMILY SSF51735 13 252 2.55E-80 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS17740 ef603dd7cff06cf040dfdce29364de0a 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 7.5E-42 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS17740 ef603dd7cff06cf040dfdce29364de0a 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 7.5E-42 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS17740 ef603dd7cff06cf040dfdce29364de0a 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 7.5E-42 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS17740 ef603dd7cff06cf040dfdce29364de0a 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 7.5E-42 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS17740 ef603dd7cff06cf040dfdce29364de0a 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 7.5E-42 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS17740 ef603dd7cff06cf040dfdce29364de0a 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 7.5E-42 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS34290 34be756a611350188161dab3d4b2073e 271 PIRSF PIRSF017393 2 271 2.1E-106 T 29-03-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type SMALA_RS34290 34be756a611350188161dab3d4b2073e 271 Gene3D G3DSA:3.40.50.150 1 271 1.0E-54 T 29-03-2018 SMALA_RS34290 34be756a611350188161dab3d4b2073e 271 Pfam PF04672 S-adenosyl methyltransferase 6 271 2.2E-117 T 29-03-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type SMALA_RS34290 34be756a611350188161dab3d4b2073e 271 SUPERFAMILY SSF53335 15 256 2.54E-43 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS19020 16eb59031a33d4ada0eae3d68ace049e 171 TIGRFAM TIGR03941 tRNA_deam_assoc: putative tRNA adenosine deaminase-associated protein 2 163 1.0E-27 T 29-03-2018 IPR023869 tRNA adenosine deaminase-associated protein, putative SMALA_RS04950 7b8cebe79a78067f34ca5e5498390435 156 SUPERFAMILY SSF69118 15 152 4.32E-39 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 SMALA_RS04950 7b8cebe79a78067f34ca5e5498390435 156 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 31 80 8.5E-20 T 29-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SMALA_RS04950 7b8cebe79a78067f34ca5e5498390435 156 Pfam PF02627 Carboxymuconolactone decarboxylase family 24 96 1.2E-19 T 29-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SMALA_RS04950 7b8cebe79a78067f34ca5e5498390435 156 Gene3D G3DSA:1.20.1290.10 1 154 4.7E-35 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 SMALA_RS34740 3079d7afe048e7f3ac52aee6037d8454 398 Gene3D G3DSA:3.40.640.10 48 291 3.9E-48 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS34740 3079d7afe048e7f3ac52aee6037d8454 398 Gene3D G3DSA:3.90.1150.10 292 397 2.9E-16 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS34740 3079d7afe048e7f3ac52aee6037d8454 398 Pfam PF00155 Aminotransferase class I and II 38 391 1.2E-54 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMALA_RS34740 3079d7afe048e7f3ac52aee6037d8454 398 SUPERFAMILY SSF53383 34 393 7.53E-93 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS34740 3079d7afe048e7f3ac52aee6037d8454 398 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 246 255 - T 29-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 SMALA_RS32825 64d24e08180906b0529cf44e91e3461f 165 Gene3D G3DSA:3.30.530.20 4 151 5.0E-22 T 29-03-2018 IPR023393 START-like domain SMALA_RS32825 64d24e08180906b0529cf44e91e3461f 165 SUPERFAMILY SSF55961 7 145 4.47E-19 T 29-03-2018 SMALA_RS32825 64d24e08180906b0529cf44e91e3461f 165 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 9 145 7.1E-11 T 29-03-2018 IPR019587 Polyketide cyclase/dehydrase SMALA_RS40060 35e58e1bcf8ad030d15740e04e6e61f0 270 Pfam PF00248 Aldo/keto reductase family 25 263 1.3E-32 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS40060 35e58e1bcf8ad030d15740e04e6e61f0 270 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 129 146 - T 29-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 SMALA_RS40060 35e58e1bcf8ad030d15740e04e6e61f0 270 PRINTS PR00069 Aldo-keto reductase signature 98 116 2.0E-32 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMALA_RS40060 35e58e1bcf8ad030d15740e04e6e61f0 270 PRINTS PR00069 Aldo-keto reductase signature 44 68 2.0E-32 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMALA_RS40060 35e58e1bcf8ad030d15740e04e6e61f0 270 PRINTS PR00069 Aldo-keto reductase signature 199 223 2.0E-32 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMALA_RS40060 35e58e1bcf8ad030d15740e04e6e61f0 270 PRINTS PR00069 Aldo-keto reductase signature 163 192 2.0E-32 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMALA_RS40060 35e58e1bcf8ad030d15740e04e6e61f0 270 PRINTS PR00069 Aldo-keto reductase signature 129 146 2.0E-32 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMALA_RS40060 35e58e1bcf8ad030d15740e04e6e61f0 270 Gene3D G3DSA:3.20.20.100 14 270 5.1E-67 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS40060 35e58e1bcf8ad030d15740e04e6e61f0 270 SUPERFAMILY SSF51430 18 265 3.14E-67 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS40060 35e58e1bcf8ad030d15740e04e6e61f0 270 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 48 65 - T 29-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 SMALA_RS40060 35e58e1bcf8ad030d15740e04e6e61f0 270 PIRSF PIRSF000097 118 270 7.3E-22 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMALA_RS40060 35e58e1bcf8ad030d15740e04e6e61f0 270 PIRSF PIRSF000097 15 122 1.4E-28 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMALA_RS33920 8308be79439463cf3c16e788d87c9978 294 Gene3D G3DSA:3.90.850.10 22 294 7.2E-50 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 SMALA_RS33920 8308be79439463cf3c16e788d87c9978 294 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 115 286 2.1E-13 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 SMALA_RS33920 8308be79439463cf3c16e788d87c9978 294 SUPERFAMILY SSF56529 26 287 3.4E-76 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 SMALA_RS16945 0ef04745a24e27095e3616725be8dac8 383 SUPERFAMILY SSF54001 268 373 3.14E-42 T 29-03-2018 SMALA_RS16945 0ef04745a24e27095e3616725be8dac8 383 Gene3D G3DSA:3.90.1720.10 164 315 1.6E-20 T 29-03-2018 SMALA_RS16945 0ef04745a24e27095e3616725be8dac8 383 Gene3D G3DSA:1.20.1170.10 21 111 0.003 T 29-03-2018 SMALA_RS16945 0ef04745a24e27095e3616725be8dac8 383 Gene3D G3DSA:2.30.260.10 316 376 7.7E-21 T 29-03-2018 SMALA_RS16945 0ef04745a24e27095e3616725be8dac8 383 Pfam PF00877 NlpC/P60 family 283 371 8.7E-26 T 29-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain SMALA_RS06465 5d70169b7dbd64d55aca6f4496f867d4 285 Gene3D G3DSA:3.40.50.720 82 285 1.6E-13 T 29-03-2018 SMALA_RS06465 5d70169b7dbd64d55aca6f4496f867d4 285 SUPERFAMILY SSF51735 4 278 9.07E-55 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS06465 5d70169b7dbd64d55aca6f4496f867d4 285 Pfam PF13460 NAD(P)H-binding 9 183 2.1E-24 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS06465 5d70169b7dbd64d55aca6f4496f867d4 285 Gene3D G3DSA:3.40.50.720 3 72 3.6E-17 T 29-03-2018 SMALA_RS30745 64b34b4a655814af17ddff653bb36469 158 Gene3D G3DSA:1.10.287.100 120 157 1.0E-12 T 29-03-2018 SMALA_RS30745 64b34b4a655814af17ddff653bb36469 158 Pfam PF12802 MarR family 47 105 2.7E-8 T 29-03-2018 SMALA_RS30745 64b34b4a655814af17ddff653bb36469 158 SUPERFAMILY SSF46785 20 155 7.49E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS30745 64b34b4a655814af17ddff653bb36469 158 Gene3D G3DSA:1.10.10.10 35 119 3.4E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS30745 64b34b4a655814af17ddff653bb36469 158 SMART SM00347 41 142 5.7E-14 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS35295 4af999e82177f0aa7d8271028aadb06d 261 Pfam PF06386 Gas vesicle synthesis protein GvpL/GvpF 8 249 1.1E-64 T 29-03-2018 IPR009430 Gas vesicle protein GvpL/GvpF GO:0031411|GO:0031412 SMALA_RS15110 7b32e140ad66358ac08158a1d0a03838 336 SMART SM00530 10 84 8.2E-9 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS15110 7b32e140ad66358ac08158a1d0a03838 336 SUPERFAMILY SSF51735 137 299 4.21E-38 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS15110 7b32e140ad66358ac08158a1d0a03838 336 Pfam PF13560 Helix-turn-helix domain 6 87 1.8E-17 T 29-03-2018 SMALA_RS15110 7b32e140ad66358ac08158a1d0a03838 336 SUPERFAMILY SSF47413 33 81 7.11E-8 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS15110 7b32e140ad66358ac08158a1d0a03838 336 Gene3D G3DSA:1.10.260.40 1 80 8.4E-16 T 29-03-2018 SMALA_RS15110 7b32e140ad66358ac08158a1d0a03838 336 Gene3D G3DSA:3.90.180.10 81 177 8.1E-18 T 29-03-2018 SMALA_RS15110 7b32e140ad66358ac08158a1d0a03838 336 Gene3D G3DSA:3.40.50.20 178 329 3.2E-20 T 29-03-2018 SMALA_RS15110 7b32e140ad66358ac08158a1d0a03838 336 Pfam PF00107 Zinc-binding dehydrogenase 173 295 3.2E-17 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMALA_RS35495 1667096aaa55734b47c8ceecc4065760 274 Gene3D G3DSA:1.10.3720.10 9 263 2.1E-37 T 29-03-2018 SMALA_RS35495 1667096aaa55734b47c8ceecc4065760 274 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 84 263 7.9E-16 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS35495 1667096aaa55734b47c8ceecc4065760 274 SUPERFAMILY SSF161098 5 273 2.52E-66 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS30795 588e186c8b2facc58d63e9f4e0581b1f 311 Gene3D G3DSA:3.40.190.10 108 201 1.1E-29 T 29-03-2018 SMALA_RS30795 588e186c8b2facc58d63e9f4e0581b1f 311 Gene3D G3DSA:3.40.190.10 1 107 1.8E-34 T 29-03-2018 SMALA_RS30795 588e186c8b2facc58d63e9f4e0581b1f 311 SUPERFAMILY SSF53850 7 219 4.1E-64 T 29-03-2018 SMALA_RS30795 588e186c8b2facc58d63e9f4e0581b1f 311 PRINTS PR00151 Porphobilinogen deaminase signature 45 65 1.4E-26 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMALA_RS30795 588e186c8b2facc58d63e9f4e0581b1f 311 PRINTS PR00151 Porphobilinogen deaminase signature 126 143 1.4E-26 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMALA_RS30795 588e186c8b2facc58d63e9f4e0581b1f 311 PRINTS PR00151 Porphobilinogen deaminase signature 76 95 1.4E-26 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMALA_RS30795 588e186c8b2facc58d63e9f4e0581b1f 311 PRINTS PR00151 Porphobilinogen deaminase signature 145 162 1.4E-26 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMALA_RS30795 588e186c8b2facc58d63e9f4e0581b1f 311 PRINTS PR00151 Porphobilinogen deaminase signature 232 249 1.4E-26 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMALA_RS30795 588e186c8b2facc58d63e9f4e0581b1f 311 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 233 249 - T 29-03-2018 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMALA_RS30795 588e186c8b2facc58d63e9f4e0581b1f 311 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 7 215 3.8E-61 T 29-03-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMALA_RS30795 588e186c8b2facc58d63e9f4e0581b1f 311 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 7 300 1.0E-93 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMALA_RS30795 588e186c8b2facc58d63e9f4e0581b1f 311 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 6 300 32.826 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMALA_RS30795 588e186c8b2facc58d63e9f4e0581b1f 311 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 227 298 6.9E-13 T 29-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMALA_RS30795 588e186c8b2facc58d63e9f4e0581b1f 311 SUPERFAMILY SSF54782 227 309 3.53E-18 T 29-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMALA_RS30795 588e186c8b2facc58d63e9f4e0581b1f 311 PIRSF PIRSF001438 1 311 3.6E-94 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMALA_RS30795 588e186c8b2facc58d63e9f4e0581b1f 311 Gene3D G3DSA:3.30.160.40 226 307 3.3E-17 T 29-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMALA_RS13965 5a93e9b61990fffac3b1341172595b03 131 Pfam PF05025 RbsD / FucU transport protein family 2 129 5.2E-37 T 29-03-2018 IPR007721 D-ribose pyranase RbsD/L-fucose mutarotase FucU GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 SMALA_RS13965 5a93e9b61990fffac3b1341172595b03 131 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 15 24 - T 29-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 SMALA_RS13965 5a93e9b61990fffac3b1341172595b03 131 Hamap MF_01661 D-ribose pyranase [rbsD]. 1 131 29.199 T 29-03-2018 IPR023064 D-ribose pyranase GO:0016872 SMALA_RS13965 5a93e9b61990fffac3b1341172595b03 131 Gene3D G3DSA:3.40.1650.10 3 131 2.5E-29 T 29-03-2018 IPR023750 RbsD-like domain GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 SMALA_RS13965 5a93e9b61990fffac3b1341172595b03 131 SUPERFAMILY SSF102546 2 131 1.83E-36 T 29-03-2018 IPR023750 RbsD-like domain GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 SMALA_RS27175 449126891e77e7dbac432da2956114b2 341 SUPERFAMILY SSF53784 1 332 5.1E-120 T 29-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMALA_RS27175 449126891e77e7dbac432da2956114b2 341 ProSitePatterns PS00433 Phosphofructokinase signature. 266 284 - T 29-03-2018 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMALA_RS27175 449126891e77e7dbac432da2956114b2 341 Gene3D G3DSA:3.40.50.450 182 323 8.1E-18 T 29-03-2018 SMALA_RS27175 449126891e77e7dbac432da2956114b2 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 93 109 7.9E-74 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMALA_RS27175 449126891e77e7dbac432da2956114b2 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 5 24 7.9E-74 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMALA_RS27175 449126891e77e7dbac432da2956114b2 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 212 224 7.9E-74 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMALA_RS27175 449126891e77e7dbac432da2956114b2 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 120 137 7.9E-74 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMALA_RS27175 449126891e77e7dbac432da2956114b2 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 31 44 7.9E-74 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMALA_RS27175 449126891e77e7dbac432da2956114b2 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 138 156 7.9E-74 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMALA_RS27175 449126891e77e7dbac432da2956114b2 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 158 174 7.9E-74 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMALA_RS27175 449126891e77e7dbac432da2956114b2 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 262 284 7.9E-74 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMALA_RS27175 449126891e77e7dbac432da2956114b2 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 176 193 7.9E-74 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMALA_RS27175 449126891e77e7dbac432da2956114b2 341 TIGRFAM TIGR02483 PFK_mixed: phosphofructokinase 2 323 1.2E-143 T 29-03-2018 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 SMALA_RS27175 449126891e77e7dbac432da2956114b2 341 PIRSF PIRSF000532 1 340 2.9E-114 T 29-03-2018 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 SMALA_RS27175 449126891e77e7dbac432da2956114b2 341 Gene3D G3DSA:3.40.50.450 1 181 2.9E-68 T 29-03-2018 SMALA_RS27175 449126891e77e7dbac432da2956114b2 341 Hamap MF_01976 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase [pfp]. 1 341 43.078 T 29-03-2018 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 SMALA_RS27175 449126891e77e7dbac432da2956114b2 341 Pfam PF00365 Phosphofructokinase 2 297 7.3E-102 T 29-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMALA_RS02380 6590a09d845ba00e53c2c0ab182cceee 209 Gene3D G3DSA:3.40.109.10 23 207 3.7E-29 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMALA_RS02380 6590a09d845ba00e53c2c0ab182cceee 209 SUPERFAMILY SSF55469 34 201 2.49E-36 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMALA_RS02380 6590a09d845ba00e53c2c0ab182cceee 209 Pfam PF00881 Nitroreductase family 31 187 2.5E-13 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 SMALA_RS13905 ebe98270c9dcb4a67c0f1acaaf370213 339 Gene3D G3DSA:3.40.50.720 1 139 9.7E-32 T 29-03-2018 SMALA_RS13905 ebe98270c9dcb4a67c0f1acaaf370213 339 SUPERFAMILY SSF51735 5 157 1.17E-38 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS13905 ebe98270c9dcb4a67c0f1acaaf370213 339 Gene3D G3DSA:3.30.360.10 140 338 2.7E-28 T 29-03-2018 SMALA_RS13905 ebe98270c9dcb4a67c0f1acaaf370213 339 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 8 128 1.9E-23 T 29-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 SMALA_RS13905 ebe98270c9dcb4a67c0f1acaaf370213 339 Hamap MF_01671 Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase [iolG]. 5 339 47.345 T 29-03-2018 IPR023794 Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase GO:0019310|GO:0050112|GO:0055114 KEGG: 00521+1.1.1.18|KEGG: 00562+1.1.1.18|MetaCyc: PWY-5940|MetaCyc: PWY-7237|MetaCyc: PWY-7241 SMALA_RS13905 ebe98270c9dcb4a67c0f1acaaf370213 339 SUPERFAMILY SSF55347 136 288 6.1E-13 T 29-03-2018 SMALA_RS21650 c38f342b2422b7a8b34ec62f8dd31745 203 Pfam PF04542 Sigma-70 region 2 17 78 4.8E-7 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS21650 c38f342b2422b7a8b34ec62f8dd31745 203 SUPERFAMILY SSF88946 2 75 5.49E-12 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS21650 c38f342b2422b7a8b34ec62f8dd31745 203 Gene3D G3DSA:1.10.10.10 72 162 2.8E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS21650 c38f342b2422b7a8b34ec62f8dd31745 203 SUPERFAMILY SSF88659 90 162 8.6E-17 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS21650 c38f342b2422b7a8b34ec62f8dd31745 203 Gene3D G3DSA:1.10.1740.10 1 71 2.5E-11 T 29-03-2018 SMALA_RS21650 c38f342b2422b7a8b34ec62f8dd31745 203 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 34 65 - T 29-03-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS21650 c38f342b2422b7a8b34ec62f8dd31745 203 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 10 159 1.5E-25 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS21650 c38f342b2422b7a8b34ec62f8dd31745 203 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 5 162 8.7E-61 T 29-03-2018 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 SMALA_RS21650 c38f342b2422b7a8b34ec62f8dd31745 203 Pfam PF08281 Sigma-70, region 4 104 155 7.6E-17 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS04115 b1f9f0c7507f3c1740639d7d1b0eedb6 393 Gene3D G3DSA:1.10.260.40 1 66 3.2E-13 T 29-03-2018 SMALA_RS04115 b1f9f0c7507f3c1740639d7d1b0eedb6 393 SUPERFAMILY SSF47413 7 68 8.85E-12 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS04115 b1f9f0c7507f3c1740639d7d1b0eedb6 393 SMART SM00530 10 65 8.2E-10 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS04115 b1f9f0c7507f3c1740639d7d1b0eedb6 393 Gene3D G3DSA:1.25.40.10 178 377 1.1E-4 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS04115 b1f9f0c7507f3c1740639d7d1b0eedb6 393 Pfam PF13560 Helix-turn-helix domain 10 62 7.0E-9 T 29-03-2018 SMALA_RS06415 25dd2077e4c652c4e0ce55d7be1ed99e 224 Gene3D G3DSA:3.40.50.150 1 222 8.6E-45 T 29-03-2018 SMALA_RS06415 25dd2077e4c652c4e0ce55d7be1ed99e 224 Pfam PF01596 O-methyltransferase 16 221 1.4E-66 T 29-03-2018 IPR002935 O-methyltransferase, family 3 GO:0008171 SMALA_RS06415 25dd2077e4c652c4e0ce55d7be1ed99e 224 SUPERFAMILY SSF53335 8 221 3.79E-47 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS41695 3e61b77fd2bbcd7a577eb0f82dfb911c 684 SUPERFAMILY SSF53649 147 434 1.6E-6 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 SMALA_RS41695 3e61b77fd2bbcd7a577eb0f82dfb911c 684 Pfam PF05506 Domain of unknown function (DUF756) 586 668 3.5E-16 T 29-03-2018 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 SMALA_RS41695 3e61b77fd2bbcd7a577eb0f82dfb911c 684 Pfam PF05506 Domain of unknown function (DUF756) 498 579 4.0E-20 T 29-03-2018 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 SMALA_RS41695 3e61b77fd2bbcd7a577eb0f82dfb911c 684 Gene3D G3DSA:3.40.720.10 101 435 1.6E-26 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 SMALA_RS41695 3e61b77fd2bbcd7a577eb0f82dfb911c 684 Pfam PF04185 Phosphoesterase family 44 429 2.2E-118 T 29-03-2018 IPR007312 Phosphoesterase GO:0016788 SMALA_RS41695 3e61b77fd2bbcd7a577eb0f82dfb911c 684 TIGRFAM TIGR03396 PC_PLC: phospholipase C, phosphocholine-specific 5 681 3.3E-258 T 29-03-2018 IPR017767 Bacterial phospholipase C, phosphocholine-specific GO:0034480 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 SMALA_RS41695 3e61b77fd2bbcd7a577eb0f82dfb911c 684 Gene3D G3DSA:2.60.290.11 545 684 0.001 T 29-03-2018 SMALA_RS10490 3e7333b913f2236b1fe22b9f37005dad 453 Pfam PF05991 YacP-like NYN domain 332 451 7.4E-16 T 29-03-2018 IPR010298 Protein of unknown function DUF901 SMALA_RS10490 3e7333b913f2236b1fe22b9f37005dad 453 Gene3D G3DSA:1.20.1170.10 70 255 2.2E-9 T 29-03-2018 SMALA_RS02885 f90de5f038a971b803e71d5087d71b50 88 Pfam PF04226 Transglycosylase associated protein 33 83 5.8E-10 T 29-03-2018 IPR007341 Transglycosylase-associated protein GO:0016021 SMALA_RS27610 23aef92df9f3d12d31b42d342f06d4f2 383 Gene3D G3DSA:3.40.50.620 12 229 1.5E-54 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS27610 23aef92df9f3d12d31b42d342f06d4f2 383 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 17 373 36.183 T 29-03-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 SMALA_RS27610 23aef92df9f3d12d31b42d342f06d4f2 383 Gene3D G3DSA:2.40.30.10 295 382 2.1E-20 T 29-03-2018 SMALA_RS27610 23aef92df9f3d12d31b42d342f06d4f2 383 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 19 372 1.2E-89 T 29-03-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 SMALA_RS27610 23aef92df9f3d12d31b42d342f06d4f2 383 Gene3D G3DSA:2.30.30.280 230 294 3.9E-18 T 29-03-2018 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 Reactome: R-HSA-6787450 SMALA_RS27610 23aef92df9f3d12d31b42d342f06d4f2 383 SUPERFAMILY SSF52402 18 261 3.09E-46 T 29-03-2018 SMALA_RS27610 23aef92df9f3d12d31b42d342f06d4f2 383 Pfam PF03054 tRNA methyl transferase 18 372 4.3E-119 T 29-03-2018 SMALA_RS12855 036cba86dfd7300aa949efcdf3db6f90 225 Pfam PF00072 Response regulator receiver domain 5 119 3.4E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS12855 036cba86dfd7300aa949efcdf3db6f90 225 Gene3D G3DSA:1.10.10.10 130 224 7.5E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS12855 036cba86dfd7300aa949efcdf3db6f90 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 174 190 1.2E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS12855 036cba86dfd7300aa949efcdf3db6f90 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 160 174 1.2E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS12855 036cba86dfd7300aa949efcdf3db6f90 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 190 202 1.2E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS12855 036cba86dfd7300aa949efcdf3db6f90 225 Gene3D G3DSA:3.40.50.2300 2 129 3.7E-37 T 29-03-2018 SMALA_RS12855 036cba86dfd7300aa949efcdf3db6f90 225 SMART SM00421 157 214 5.3E-24 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS12855 036cba86dfd7300aa949efcdf3db6f90 225 SUPERFAMILY SSF52172 3 128 9.25E-34 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS12855 036cba86dfd7300aa949efcdf3db6f90 225 SUPERFAMILY SSF46894 149 220 8.84E-21 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS12855 036cba86dfd7300aa949efcdf3db6f90 225 SMART SM00448 3 118 6.2E-31 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS12855 036cba86dfd7300aa949efcdf3db6f90 225 Pfam PF00196 Bacterial regulatory proteins, luxR family 159 213 1.3E-16 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS06810 73c6d88d4a177b3ef23f50d13091eded 452 SMART SM00829 46 412 6.4E-9 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS06810 73c6d88d4a177b3ef23f50d13091eded 452 TIGRFAM TIGR01751 crot-CoA-red: crotonyl-CoA carboxylase/reductase 32 425 3.2E-160 T 29-03-2018 IPR010085 Crotonyl-CoA reductase GO:0043880 KEGG: 00650+1.3.1.86 SMALA_RS06810 73c6d88d4a177b3ef23f50d13091eded 452 Pfam PF00107 Zinc-binding dehydrogenase 233 376 8.6E-28 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMALA_RS06810 73c6d88d4a177b3ef23f50d13091eded 452 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 222 243 - T 29-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 SMALA_RS06810 73c6d88d4a177b3ef23f50d13091eded 452 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 65 186 4.8E-6 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS06810 73c6d88d4a177b3ef23f50d13091eded 452 Gene3D G3DSA:3.90.180.10 6 414 1.2E-59 T 29-03-2018 SMALA_RS06810 73c6d88d4a177b3ef23f50d13091eded 452 SUPERFAMILY SSF51735 192 380 1.08E-31 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS06810 73c6d88d4a177b3ef23f50d13091eded 452 SUPERFAMILY SSF50129 49 227 9.75E-29 T 29-03-2018 IPR011032 GroES-like SMALA_RS09635 b1ccbfa2d153e135d74b0093c08e57e4 218 SUPERFAMILY SSF56281 22 214 5.69E-44 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS09635 b1ccbfa2d153e135d74b0093c08e57e4 218 Pfam PF00753 Metallo-beta-lactamase superfamily 29 197 5.7E-13 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS09635 b1ccbfa2d153e135d74b0093c08e57e4 218 Gene3D G3DSA:3.60.15.10 19 217 3.7E-33 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS09635 b1ccbfa2d153e135d74b0093c08e57e4 218 SMART SM00849 32 197 3.0E-32 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS24645 1a92dbfd31ae6adf3de3a3330b96447b 214 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 193 213 9.1E-5 T 29-03-2018 SMALA_RS24645 1a92dbfd31ae6adf3de3a3330b96447b 214 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 173 192 9.1E-5 T 29-03-2018 SMALA_RS24645 1a92dbfd31ae6adf3de3a3330b96447b 214 PRINTS PR01021 OMPA domain signature 110 132 1.1E-5 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 SMALA_RS24645 1a92dbfd31ae6adf3de3a3330b96447b 214 PRINTS PR01021 OMPA domain signature 140 155 1.1E-5 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 SMALA_RS24645 1a92dbfd31ae6adf3de3a3330b96447b 214 PRINTS PR01021 OMPA domain signature 155 171 1.1E-5 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 SMALA_RS24645 1a92dbfd31ae6adf3de3a3330b96447b 214 SUPERFAMILY SSF103088 100 210 6.28E-27 T 29-03-2018 IPR006665 OmpA-like domain SMALA_RS24645 1a92dbfd31ae6adf3de3a3330b96447b 214 Gene3D G3DSA:3.30.1330.60 70 214 4.1E-28 T 29-03-2018 IPR006665 OmpA-like domain SMALA_RS24645 1a92dbfd31ae6adf3de3a3330b96447b 214 Pfam PF00691 OmpA family 110 204 5.4E-15 T 29-03-2018 IPR006665 OmpA-like domain SMALA_RS03935 6952d2012c69a4bff24d10b09448d9e8 473 SUPERFAMILY SSF103473 26 215 6.15E-39 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS03935 6952d2012c69a4bff24d10b09448d9e8 473 SUPERFAMILY SSF103473 277 466 6.15E-39 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS03935 6952d2012c69a4bff24d10b09448d9e8 473 Pfam PF07690 Major Facilitator Superfamily 302 466 1.2E-8 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS03935 6952d2012c69a4bff24d10b09448d9e8 473 Pfam PF07690 Major Facilitator Superfamily 35 211 5.0E-10 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS03935 6952d2012c69a4bff24d10b09448d9e8 473 Gene3D G3DSA:1.20.1250.20 290 466 1.7E-13 T 29-03-2018 SMALA_RS03935 6952d2012c69a4bff24d10b09448d9e8 473 Gene3D G3DSA:1.20.1250.20 14 222 6.1E-13 T 29-03-2018 SMALA_RS28750 0cdf2d6205ab2e11171614299310cfdf 211 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 75 97 - T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 SMALA_RS28750 0cdf2d6205ab2e11171614299310cfdf 211 PIRSF PIRSF000847 23 208 5.1E-43 T 29-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 SMALA_RS28750 0cdf2d6205ab2e11171614299310cfdf 211 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 27 196 4.3E-39 T 29-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 SMALA_RS28750 0cdf2d6205ab2e11171614299310cfdf 211 Pfam PF01066 CDP-alcohol phosphatidyltransferase 27 97 5.5E-16 T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 SMALA_RS34435 453a7830ae4b58b94088193992ea4038 288 SUPERFAMILY SSF103481 212 287 3.66E-12 T 29-03-2018 SMALA_RS34435 453a7830ae4b58b94088193992ea4038 288 Pfam PF00892 EamA-like transporter family 3 131 1.3E-11 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SMALA_RS34435 453a7830ae4b58b94088193992ea4038 288 Pfam PF00892 EamA-like transporter family 146 286 6.8E-10 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SMALA_RS34435 453a7830ae4b58b94088193992ea4038 288 SUPERFAMILY SSF103481 38 134 1.83E-11 T 29-03-2018 SMALA_RS29040 bf9e5228ec646daaa21c8d753cfab0e6 317 Gene3D G3DSA:1.20.120.530 168 301 6.6E-24 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS29040 bf9e5228ec646daaa21c8d753cfab0e6 317 Pfam PF00392 Bacterial regulatory proteins, gntR family 88 147 2.6E-14 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS29040 bf9e5228ec646daaa21c8d753cfab0e6 317 SUPERFAMILY SSF46785 81 151 2.55E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS29040 bf9e5228ec646daaa21c8d753cfab0e6 317 SMART SM00345 89 147 1.1E-11 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS29040 bf9e5228ec646daaa21c8d753cfab0e6 317 SUPERFAMILY SSF48008 173 299 1.05E-24 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS29040 bf9e5228ec646daaa21c8d753cfab0e6 317 Gene3D G3DSA:1.10.10.10 75 159 1.5E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS29040 bf9e5228ec646daaa21c8d753cfab0e6 317 SMART SM00895 176 300 5.1E-20 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS29040 bf9e5228ec646daaa21c8d753cfab0e6 317 Pfam PF07729 FCD domain 176 298 1.4E-20 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS41840 11f9a5a76d0caa8b27c47dcd9f8949db 388 Gene3D G3DSA:3.40.710.10 3 388 3.9E-70 T 29-03-2018 SMALA_RS41840 11f9a5a76d0caa8b27c47dcd9f8949db 388 Pfam PF00144 Beta-lactamase 22 374 2.4E-61 T 29-03-2018 IPR001466 Beta-lactamase-related SMALA_RS41840 11f9a5a76d0caa8b27c47dcd9f8949db 388 SUPERFAMILY SSF56601 15 378 4.18E-65 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMALA_RS37925 007d2563b6f8da70d944a31629752929 288 Gene3D G3DSA:1.10.10.60 59 114 7.5E-8 T 29-03-2018 SMALA_RS37925 007d2563b6f8da70d944a31629752929 288 SUPERFAMILY SSF46689 3 53 3.85E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS37925 007d2563b6f8da70d944a31629752929 288 Pfam PF12833 Helix-turn-helix domain 25 103 7.1E-17 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS37925 007d2563b6f8da70d944a31629752929 288 SUPERFAMILY SSF55136 126 285 2.88E-19 T 29-03-2018 SMALA_RS37925 007d2563b6f8da70d944a31629752929 288 Gene3D G3DSA:3.20.80.10 115 284 1.0E-33 T 29-03-2018 IPR011256 Regulatory factor, effector binding domain SMALA_RS37925 007d2563b6f8da70d944a31629752929 288 Gene3D G3DSA:1.10.10.60 2 58 5.4E-11 T 29-03-2018 SMALA_RS37925 007d2563b6f8da70d944a31629752929 288 SMART SM00871 126 284 5.8E-21 T 29-03-2018 IPR010499 Bacterial transcription activator, effector binding SMALA_RS37925 007d2563b6f8da70d944a31629752929 288 SUPERFAMILY SSF46689 55 105 1.79E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS37925 007d2563b6f8da70d944a31629752929 288 SMART SM00342 19 102 2.3E-21 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS37925 007d2563b6f8da70d944a31629752929 288 Pfam PF06445 GyrI-like small molecule binding domain 126 283 1.3E-23 T 29-03-2018 IPR029442 GyrI-like small molecule binding domain SMALA_RS21815 a010dcf35b3eb2d58f5d5e41c482350c 92 Gene3D G3DSA:3.40.30.10 15 91 4.1E-10 T 29-03-2018 SMALA_RS21815 a010dcf35b3eb2d58f5d5e41c482350c 92 Pfam PF05768 Glutaredoxin-like domain (DUF836) 17 90 1.1E-18 T 29-03-2018 IPR008554 Glutaredoxin-like SMALA_RS21815 a010dcf35b3eb2d58f5d5e41c482350c 92 SUPERFAMILY SSF52833 13 91 6.42E-18 T 29-03-2018 IPR012336 Thioredoxin-like fold SMALA_RS13995 498fdad65cd784e82ff9d5938207f27c 386 Gene3D G3DSA:3.40.50.720 1 156 4.2E-27 T 29-03-2018 SMALA_RS13995 498fdad65cd784e82ff9d5938207f27c 386 Gene3D G3DSA:3.30.360.10 157 385 3.8E-38 T 29-03-2018 SMALA_RS13995 498fdad65cd784e82ff9d5938207f27c 386 SUPERFAMILY SSF55347 149 349 4.36E-30 T 29-03-2018 SMALA_RS13995 498fdad65cd784e82ff9d5938207f27c 386 SUPERFAMILY SSF51735 4 176 4.77E-28 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS13995 498fdad65cd784e82ff9d5938207f27c 386 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 50 140 2.7E-8 T 29-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 SMALA_RS31380 0dc3c99e766982fb31d6c99d7e88584c 380 Pfam PF07994 Myo-inositol-1-phosphate synthase 60 356 2.0E-21 T 29-03-2018 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 SMALA_RS31380 0dc3c99e766982fb31d6c99d7e88584c 380 SUPERFAMILY SSF51735 317 378 2.84E-57 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS31380 0dc3c99e766982fb31d6c99d7e88584c 380 SUPERFAMILY SSF51735 14 213 2.84E-57 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS31380 0dc3c99e766982fb31d6c99d7e88584c 380 SUPERFAMILY SSF55347 214 318 7.46E-28 T 29-03-2018 SMALA_RS31380 0dc3c99e766982fb31d6c99d7e88584c 380 Pfam PF01658 Myo-inositol-1-phosphate synthase 215 319 2.2E-24 T 29-03-2018 IPR013021 Myo-inositol-1-phosphate synthase, GAPDH-like KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 SMALA_RS31380 0dc3c99e766982fb31d6c99d7e88584c 380 PIRSF PIRSF015578 7 368 8.3E-85 T 29-03-2018 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 SMALA_RS31380 0dc3c99e766982fb31d6c99d7e88584c 380 Gene3D G3DSA:3.40.50.720 7 226 2.4E-83 T 29-03-2018 SMALA_RS31380 0dc3c99e766982fb31d6c99d7e88584c 380 Gene3D G3DSA:3.40.50.720 299 372 0.012 T 29-03-2018 SMALA_RS31380 0dc3c99e766982fb31d6c99d7e88584c 380 Gene3D G3DSA:3.30.360.10 227 298 6.8E-25 T 29-03-2018 SMALA_RS25930 5c0a8da7ec32813bb9f03c6350e2fb1e 213 Gene3D G3DSA:1.10.357.10 79 204 1.7E-19 T 29-03-2018 SMALA_RS25930 5c0a8da7ec32813bb9f03c6350e2fb1e 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 2.2E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS25930 5c0a8da7ec32813bb9f03c6350e2fb1e 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 2.2E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS25930 5c0a8da7ec32813bb9f03c6350e2fb1e 213 SUPERFAMILY SSF46689 11 91 1.9E-21 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS25930 5c0a8da7ec32813bb9f03c6350e2fb1e 213 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 71 5.4E-17 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS25930 5c0a8da7ec32813bb9f03c6350e2fb1e 213 Gene3D G3DSA:1.10.10.60 58 78 4.5E-14 T 29-03-2018 SMALA_RS25930 5c0a8da7ec32813bb9f03c6350e2fb1e 213 SUPERFAMILY SSF48498 92 203 1.91E-26 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS25930 5c0a8da7ec32813bb9f03c6350e2fb1e 213 Gene3D G3DSA:1.10.10.60 2 57 6.3E-21 T 29-03-2018 SMALA_RS11270 7e67b6d4ace59dc40e8f3db90df2d7a7 300 PRINTS PR00412 Epoxide hydrolase signature 271 293 1.8E-6 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS11270 7e67b6d4ace59dc40e8f3db90df2d7a7 300 PRINTS PR00412 Epoxide hydrolase signature 104 117 1.8E-6 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS11270 7e67b6d4ace59dc40e8f3db90df2d7a7 300 PRINTS PR00412 Epoxide hydrolase signature 118 131 1.8E-6 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS11270 7e67b6d4ace59dc40e8f3db90df2d7a7 300 PRINTS PR00412 Epoxide hydrolase signature 36 54 1.8E-6 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS11270 7e67b6d4ace59dc40e8f3db90df2d7a7 300 Gene3D G3DSA:3.40.50.1820 2 300 2.1E-52 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS11270 7e67b6d4ace59dc40e8f3db90df2d7a7 300 PRINTS PR00111 Alpha/beta hydrolase fold signature 118 131 7.6E-6 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS11270 7e67b6d4ace59dc40e8f3db90df2d7a7 300 PRINTS PR00111 Alpha/beta hydrolase fold signature 55 70 7.6E-6 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS11270 7e67b6d4ace59dc40e8f3db90df2d7a7 300 PRINTS PR00111 Alpha/beta hydrolase fold signature 104 117 7.6E-6 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS11270 7e67b6d4ace59dc40e8f3db90df2d7a7 300 Pfam PF00561 alpha/beta hydrolase fold 30 182 4.0E-22 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS11270 7e67b6d4ace59dc40e8f3db90df2d7a7 300 SUPERFAMILY SSF53474 4 296 8.81E-72 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS18055 de6f0a00848df7df6ed834ab50d587bd 319 SUPERFAMILY SSF53850 45 318 1.47E-43 T 29-03-2018 SMALA_RS18055 de6f0a00848df7df6ed834ab50d587bd 319 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 45 313 3.0E-49 T 29-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 SMALA_RS18055 de6f0a00848df7df6ed834ab50d587bd 319 Gene3D G3DSA:3.40.190.10 197 318 3.0E-17 T 29-03-2018 SMALA_RS18055 de6f0a00848df7df6ed834ab50d587bd 319 Gene3D G3DSA:3.40.190.10 35 192 1.4E-26 T 29-03-2018 SMALA_RS05715 681427a336e0a53ca03f48665c3ed34f 171 Gene3D G3DSA:1.10.238.10 1 74 1.5E-11 T 29-03-2018 SMALA_RS05715 681427a336e0a53ca03f48665c3ed34f 171 Gene3D G3DSA:1.10.238.10 75 159 6.4E-9 T 29-03-2018 SMALA_RS05715 681427a336e0a53ca03f48665c3ed34f 171 SMART SM00054 96 124 12.0 T 29-03-2018 IPR002048 EF-hand domain GO:0005509 SMALA_RS05715 681427a336e0a53ca03f48665c3ed34f 171 SMART SM00054 58 86 29.0 T 29-03-2018 IPR002048 EF-hand domain GO:0005509 SMALA_RS05715 681427a336e0a53ca03f48665c3ed34f 171 SMART SM00054 8 36 1.4 T 29-03-2018 IPR002048 EF-hand domain GO:0005509 SMALA_RS05715 681427a336e0a53ca03f48665c3ed34f 171 ProSitePatterns PS00018 EF-hand calcium-binding domain. 17 29 - T 29-03-2018 IPR018247 EF-Hand 1, calcium-binding site SMALA_RS05715 681427a336e0a53ca03f48665c3ed34f 171 SUPERFAMILY SSF47473 4 161 1.17E-19 T 29-03-2018 IPR011992 EF-hand domain pair SMALA_RS05715 681427a336e0a53ca03f48665c3ed34f 171 Pfam PF13499 EF-hand domain pair 9 81 3.1E-7 T 29-03-2018 IPR002048 EF-hand domain GO:0005509 SMALA_RS05715 681427a336e0a53ca03f48665c3ed34f 171 ProSitePatterns PS00018 EF-hand calcium-binding domain. 67 79 - T 29-03-2018 IPR018247 EF-Hand 1, calcium-binding site SMALA_RS03670 79c392185db1a5cfe82c5f04517a5260 388 SUPERFAMILY SSF53901 230 371 1.25E-16 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS03670 79c392185db1a5cfe82c5f04517a5260 388 PIRSF PIRSF000429 2 378 7.2E-16 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 SMALA_RS03670 79c392185db1a5cfe82c5f04517a5260 388 SUPERFAMILY SSF53901 8 226 1.36E-21 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS03670 79c392185db1a5cfe82c5f04517a5260 388 Gene3D G3DSA:3.40.47.10 2 213 1.9E-13 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS03670 79c392185db1a5cfe82c5f04517a5260 388 Gene3D G3DSA:3.40.47.10 214 380 4.6E-11 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS28855 3e462d10f24a8e240006050e861e9696 258 SUPERFAMILY SSF52540 18 251 1.52E-80 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS28855 3e462d10f24a8e240006050e861e9696 258 SMART SM00382 42 229 1.6E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS28855 3e462d10f24a8e240006050e861e9696 258 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS28855 3e462d10f24a8e240006050e861e9696 258 Gene3D G3DSA:3.40.50.300 14 257 5.4E-77 T 29-03-2018 SMALA_RS28855 3e462d10f24a8e240006050e861e9696 258 PIRSF PIRSF039085 14 257 1.8E-113 T 29-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 SMALA_RS28855 3e462d10f24a8e240006050e861e9696 258 Pfam PF00005 ABC transporter 33 181 1.6E-36 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS13630 7a64eba41487f6ac325bf47b63fc1483 347 Gene3D G3DSA:3.40.50.300 3 327 2.9E-28 T 29-03-2018 SMALA_RS13630 7a64eba41487f6ac325bf47b63fc1483 347 Pfam PF13469 Sulfotransferase family 8 195 4.2E-12 T 29-03-2018 SMALA_RS13630 7a64eba41487f6ac325bf47b63fc1483 347 SUPERFAMILY SSF52540 138 199 3.23E-23 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS13630 7a64eba41487f6ac325bf47b63fc1483 347 SUPERFAMILY SSF52540 5 84 3.23E-23 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS13630 7a64eba41487f6ac325bf47b63fc1483 347 SUPERFAMILY SSF52540 233 313 3.23E-23 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS29075 0af60e2da6c598584a5da33332d0bcad 233 SUPERFAMILY SSF46785 173 216 7.0E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS29075 0af60e2da6c598584a5da33332d0bcad 233 PIRSF PIRSF006171 10 233 3.8E-77 T 29-03-2018 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0001071|GO:0003677|GO:0005737|GO:0009605 SMALA_RS29075 0af60e2da6c598584a5da33332d0bcad 233 Gene3D G3DSA:3.40.50.2300 10 141 1.1E-29 T 29-03-2018 SMALA_RS29075 0af60e2da6c598584a5da33332d0bcad 233 Gene3D G3DSA:1.10.10.10 142 233 1.2E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS29075 0af60e2da6c598584a5da33332d0bcad 233 Pfam PF08279 HTH domain 176 215 2.1E-6 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 SMALA_RS29075 0af60e2da6c598584a5da33332d0bcad 233 SUPERFAMILY SSF52172 11 135 7.54E-33 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS29075 0af60e2da6c598584a5da33332d0bcad 233 SMART SM00448 11 124 1.7E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS29075 0af60e2da6c598584a5da33332d0bcad 233 Pfam PF00072 Response regulator receiver domain 13 124 1.5E-22 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS37570 59c221188a3bb32722ca5c54aa452b1a 421 SUPERFAMILY SSF46785 12 74 4.12E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS37570 59c221188a3bb32722ca5c54aa452b1a 421 Pfam PF00480 ROK family 88 391 1.2E-47 T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 SMALA_RS37570 59c221188a3bb32722ca5c54aa452b1a 421 Gene3D G3DSA:3.30.420.40 206 404 1.0E-52 T 29-03-2018 SMALA_RS37570 59c221188a3bb32722ca5c54aa452b1a 421 SUPERFAMILY SSF53067 87 397 1.71E-45 T 29-03-2018 SMALA_RS37570 59c221188a3bb32722ca5c54aa452b1a 421 Gene3D G3DSA:1.10.10.10 10 77 4.6E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS37570 59c221188a3bb32722ca5c54aa452b1a 421 Gene3D G3DSA:3.30.420.40 78 205 6.0E-28 T 29-03-2018 SMALA_RS16285 352588e962aeb2bd870f1280508cb4d1 487 Pfam PF09852 Predicted membrane protein (DUF2079) 59 454 3.1E-59 T 29-03-2018 IPR018650 Sulfolobus virus STSV1, Orf64 SMALA_RS41065 2b0a3a7287d8941b15e7d8280c474a1c 399 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 23 120 3.1E-10 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS41065 2b0a3a7287d8941b15e7d8280c474a1c 399 SUPERFAMILY SSF56645 22 222 2.75E-44 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMALA_RS41065 2b0a3a7287d8941b15e7d8280c474a1c 399 Gene3D G3DSA:2.40.110.10 124 223 5.3E-20 T 29-03-2018 SMALA_RS41065 2b0a3a7287d8941b15e7d8280c474a1c 399 Gene3D G3DSA:1.20.140.10 228 396 3.9E-21 T 29-03-2018 SMALA_RS41065 2b0a3a7287d8941b15e7d8280c474a1c 399 Gene3D G3DSA:1.10.540.10 11 123 1.4E-16 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS41065 2b0a3a7287d8941b15e7d8280c474a1c 399 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 126 213 5.8E-10 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 SMALA_RS41065 2b0a3a7287d8941b15e7d8280c474a1c 399 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 240 371 6.9E-19 T 29-03-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain SMALA_RS41065 2b0a3a7287d8941b15e7d8280c474a1c 399 SUPERFAMILY SSF47203 236 378 1.59E-19 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMALA_RS41065 2b0a3a7287d8941b15e7d8280c474a1c 399 PIRSF PIRSF016578 4 395 2.6E-35 T 29-03-2018 SMALA_RS32190 70672bada34b6911f105fb3d60351e73 317 Gene3D G3DSA:3.80.10.10 30 311 4.9E-43 T 29-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like SMALA_RS32190 70672bada34b6911f105fb3d60351e73 317 Pfam PF13516 Leucine Rich repeat 238 256 0.058 T 29-03-2018 IPR001611 Leucine-rich repeat GO:0005515 SMALA_RS32190 70672bada34b6911f105fb3d60351e73 317 SUPERFAMILY SSF52047 120 278 5.23E-11 T 29-03-2018 SMALA_RS28525 5e21c2808309b9108d84266607eb7bef 112 SUPERFAMILY SSF140453 12 98 5.1E-11 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like SMALA_RS28525 5e21c2808309b9108d84266607eb7bef 112 Gene3D G3DSA:1.10.287.1060 1 98 3.0E-9 T 29-03-2018 SMALA_RS28525 5e21c2808309b9108d84266607eb7bef 112 Pfam PF06013 Proteins of 100 residues with WXG 6 86 3.3E-8 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like SMALA_RS11220 06c3bdcd32d126e51e3cb147cf0f5777 641 SUPERFAMILY SSF53067 4 182 1.26E-60 T 29-03-2018 SMALA_RS11220 06c3bdcd32d126e51e3cb147cf0f5777 641 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 330 344 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 SMALA_RS11220 06c3bdcd32d126e51e3cb147cf0f5777 641 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 641 35.594 T 29-03-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613 SMALA_RS11220 06c3bdcd32d126e51e3cb147cf0f5777 641 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 189 202 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 SMALA_RS11220 06c3bdcd32d126e51e3cb147cf0f5777 641 Gene3D G3DSA:3.30.420.40 194 359 2.7E-46 T 29-03-2018 SMALA_RS11220 06c3bdcd32d126e51e3cb147cf0f5777 641 Pfam PF00012 Hsp70 protein 4 590 9.1E-239 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SMALA_RS11220 06c3bdcd32d126e51e3cb147cf0f5777 641 SUPERFAMILY SSF100920 378 534 1.57E-56 T 29-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 SMALA_RS11220 06c3bdcd32d126e51e3cb147cf0f5777 641 SUPERFAMILY SSF53067 184 376 1.36E-64 T 29-03-2018 SMALA_RS11220 06c3bdcd32d126e51e3cb147cf0f5777 641 PRINTS PR00301 70kDa heat shock protein signature 382 401 1.6E-78 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SMALA_RS11220 06c3bdcd32d126e51e3cb147cf0f5777 641 PRINTS PR00301 70kDa heat shock protein signature 359 379 1.6E-78 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SMALA_RS11220 06c3bdcd32d126e51e3cb147cf0f5777 641 PRINTS PR00301 70kDa heat shock protein signature 54 62 1.6E-78 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SMALA_RS11220 06c3bdcd32d126e51e3cb147cf0f5777 641 PRINTS PR00301 70kDa heat shock protein signature 3 16 1.6E-78 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SMALA_RS11220 06c3bdcd32d126e51e3cb147cf0f5777 641 PRINTS PR00301 70kDa heat shock protein signature 136 156 1.6E-78 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SMALA_RS11220 06c3bdcd32d126e51e3cb147cf0f5777 641 PRINTS PR00301 70kDa heat shock protein signature 463 479 1.6E-78 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SMALA_RS11220 06c3bdcd32d126e51e3cb147cf0f5777 641 PRINTS PR00301 70kDa heat shock protein signature 327 343 1.6E-78 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SMALA_RS11220 06c3bdcd32d126e51e3cb147cf0f5777 641 PRINTS PR00301 70kDa heat shock protein signature 31 43 1.6E-78 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SMALA_RS11220 06c3bdcd32d126e51e3cb147cf0f5777 641 PRINTS PR00301 70kDa heat shock protein signature 195 205 1.6E-78 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SMALA_RS11220 06c3bdcd32d126e51e3cb147cf0f5777 641 Gene3D G3DSA:1.20.1270.10 527 611 2.4E-12 T 29-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain SMALA_RS11220 06c3bdcd32d126e51e3cb147cf0f5777 641 Gene3D G3DSA:3.30.420.40 1 193 9.4E-73 T 29-03-2018 SMALA_RS11220 06c3bdcd32d126e51e3cb147cf0f5777 641 Gene3D G3DSA:2.60.34.10 384 526 2.7E-62 T 29-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 SMALA_RS11220 06c3bdcd32d126e51e3cb147cf0f5777 641 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 SMALA_RS11220 06c3bdcd32d126e51e3cb147cf0f5777 641 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 3 595 3.8E-284 T 29-03-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613 SMALA_RS32160 67b1b2759b991fff32922f83c7bb2c90 288 Pfam PF13560 Helix-turn-helix domain 17 77 1.1E-13 T 29-03-2018 SMALA_RS32160 67b1b2759b991fff32922f83c7bb2c90 288 SMART SM00530 20 75 8.2E-8 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS32160 67b1b2759b991fff32922f83c7bb2c90 288 Gene3D G3DSA:1.10.3100.10 13 168 2.2E-17 T 29-03-2018 IPR027910 YdiL-like domain SMALA_RS32160 67b1b2759b991fff32922f83c7bb2c90 288 SUPERFAMILY SSF47413 12 70 4.5E-9 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS03420 6afd88de542193562c1d7ca4ca3de8be 672 Gene3D G3DSA:3.40.50.980 104 287 8.5E-31 T 29-03-2018 SMALA_RS03420 6afd88de542193562c1d7ca4ca3de8be 672 ProSitePatterns PS00455 Putative AMP-binding domain signature. 282 293 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS03420 6afd88de542193562c1d7ca4ca3de8be 672 Gene3D G3DSA:2.30.38.10 456 534 1.6E-4 T 29-03-2018 SMALA_RS03420 6afd88de542193562c1d7ca4ca3de8be 672 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 52 108 2.4E-14 T 29-03-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 SMALA_RS03420 6afd88de542193562c1d7ca4ca3de8be 672 Gene3D G3DSA:3.40.50.980 288 447 1.6E-23 T 29-03-2018 SMALA_RS03420 6afd88de542193562c1d7ca4ca3de8be 672 SUPERFAMILY SSF56801 51 658 4.71E-123 T 29-03-2018 SMALA_RS03420 6afd88de542193562c1d7ca4ca3de8be 672 Pfam PF00501 AMP-binding enzyme 117 539 6.6E-46 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS03420 6afd88de542193562c1d7ca4ca3de8be 672 Gene3D G3DSA:3.30.300.30 537 665 5.7E-12 T 29-03-2018 SMALA_RS03420 6afd88de542193562c1d7ca4ca3de8be 672 Pfam PF13193 AMP-binding enzyme C-terminal domain 552 627 2.4E-6 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS03420 6afd88de542193562c1d7ca4ca3de8be 672 TIGRFAM TIGR01217 ac_ac_CoA_syn: acetoacetate-CoA ligase 10 667 0.0 T 29-03-2018 IPR005914 Acetoacetyl-CoA synthase GO:0006629|GO:0030729 KEGG: 00280+6.2.1.16|KEGG: 00650+6.2.1.16|Reactome: R-HSA-77111 SMALA_RS12830 0cd09753f67dcdb3b643f55598fc04d5 200 Gene3D G3DSA:3.40.630.30 1 174 2.4E-19 T 29-03-2018 SMALA_RS12830 0cd09753f67dcdb3b643f55598fc04d5 200 SUPERFAMILY SSF55729 1 22 7.44E-22 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS12830 0cd09753f67dcdb3b643f55598fc04d5 200 SUPERFAMILY SSF55729 59 180 7.44E-22 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS12830 0cd09753f67dcdb3b643f55598fc04d5 200 Pfam PF13527 Acetyltransferase (GNAT) domain 84 158 2.4E-7 T 29-03-2018 SMALA_RS15050 1e23d77c7e50ddc416d2e85f64974bd0 141 Gene3D G3DSA:3.40.140.10 1 140 1.4E-26 T 29-03-2018 SMALA_RS15050 1e23d77c7e50ddc416d2e85f64974bd0 141 SUPERFAMILY SSF102712 1 134 7.19E-27 T 29-03-2018 SMALA_RS15050 1e23d77c7e50ddc416d2e85f64974bd0 141 SMART SM00232 1 135 2.6E-25 T 29-03-2018 IPR000555 JAB1/MPN/MOV34 metalloenzyme domain GO:0005515 SMALA_RS15050 1e23d77c7e50ddc416d2e85f64974bd0 141 Pfam PF14464 Prokaryotic homologs of the JAB domain 6 114 2.4E-27 T 29-03-2018 IPR028090 JAB domain, prokaryotic SMALA_RS26355 b510c6b30cd4d46210ac5aafb6223d19 181 Gene3D G3DSA:3.40.630.30 1 89 1.8E-21 T 29-03-2018 SMALA_RS26355 b510c6b30cd4d46210ac5aafb6223d19 181 SUPERFAMILY SSF55729 1 154 1.61E-34 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS26355 b510c6b30cd4d46210ac5aafb6223d19 181 Pfam PF00583 Acetyltransferase (GNAT) family 23 139 3.8E-15 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SMALA_RS26355 b510c6b30cd4d46210ac5aafb6223d19 181 Gene3D G3DSA:3.40.630.30 90 164 1.3E-13 T 29-03-2018 SMALA_RS04525 c7e07cd94c0b9af1430ce95055ea4424 273 Gene3D G3DSA:3.40.50.300 2 238 3.0E-54 T 29-03-2018 SMALA_RS04525 c7e07cd94c0b9af1430ce95055ea4424 273 SMART SM00382 62 229 4.6E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS04525 c7e07cd94c0b9af1430ce95055ea4424 273 SUPERFAMILY SSF52540 38 236 2.89E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS04525 c7e07cd94c0b9af1430ce95055ea4424 273 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS04525 c7e07cd94c0b9af1430ce95055ea4424 273 Pfam PF00005 ABC transporter 54 179 4.7E-26 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS16805 887d6a507912b276a12bd792a1a4c64e 363 ProSitePatterns PS00211 ABC transporters family signature. 182 196 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS16805 887d6a507912b276a12bd792a1a4c64e 363 SMART SM00382 70 267 2.5E-18 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS16805 887d6a507912b276a12bd792a1a4c64e 363 Pfam PF00005 ABC transporter 62 209 4.4E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS16805 887d6a507912b276a12bd792a1a4c64e 363 Gene3D G3DSA:3.40.50.300 18 323 1.3E-74 T 29-03-2018 SMALA_RS16805 887d6a507912b276a12bd792a1a4c64e 363 SUPERFAMILY SSF52540 52 286 1.33E-76 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS16805 887d6a507912b276a12bd792a1a4c64e 363 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 54 305 5.3E-105 T 29-03-2018 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 SMALA_RS11140 92b8ed714b4fb70a5c5b88e239d9d909 244 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 38 212 5.6E-27 T 29-03-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal SMALA_RS11140 92b8ed714b4fb70a5c5b88e239d9d909 244 SMART SM00943 36 222 2.4E-37 T 29-03-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal SMALA_RS35000 de54e3ec9b1c093626a846fbb977d6dc 322 SUPERFAMILY SSF53474 26 319 8.48E-69 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS35000 de54e3ec9b1c093626a846fbb977d6dc 322 Gene3D G3DSA:3.40.50.1820 2 322 4.9E-57 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS35000 de54e3ec9b1c093626a846fbb977d6dc 322 Pfam PF07859 alpha/beta hydrolase fold 85 293 1.3E-67 T 29-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 SMALA_RS34460 1911fac186f7b0510dcb8a4dde34ae33 250 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 186 5.7E-5 T 29-03-2018 SMALA_RS34460 1911fac186f7b0510dcb8a4dde34ae33 250 SUPERFAMILY SSF51735 5 247 7.54E-74 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS34460 1911fac186f7b0510dcb8a4dde34ae33 250 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 138 166 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMALA_RS34460 1911fac186f7b0510dcb8a4dde34ae33 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 1.5E-32 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS34460 1911fac186f7b0510dcb8a4dde34ae33 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 1.5E-32 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS34460 1911fac186f7b0510dcb8a4dde34ae33 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 1.5E-32 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS34460 1911fac186f7b0510dcb8a4dde34ae33 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 1.5E-32 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS34460 1911fac186f7b0510dcb8a4dde34ae33 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.5E-32 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS34460 1911fac186f7b0510dcb8a4dde34ae33 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 1.5E-32 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS34460 1911fac186f7b0510dcb8a4dde34ae33 250 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 248 4.1E-58 T 29-03-2018 SMALA_RS34460 1911fac186f7b0510dcb8a4dde34ae33 250 Gene3D G3DSA:3.40.50.720 50 249 4.8E-59 T 29-03-2018 SMALA_RS34460 1911fac186f7b0510dcb8a4dde34ae33 250 Gene3D G3DSA:3.40.50.720 1 49 1.5E-11 T 29-03-2018 SMALA_RS38515 cc05f685f98ea0b4a3c0b513b6886001 389 Gene3D G3DSA:3.40.50.1970 16 191 1.7E-44 T 29-03-2018 SMALA_RS38515 cc05f685f98ea0b4a3c0b513b6886001 389 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 181 209 - T 29-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 SMALA_RS38515 cc05f685f98ea0b4a3c0b513b6886001 389 Pfam PF00465 Iron-containing alcohol dehydrogenase 19 380 8.8E-108 T 29-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 SMALA_RS38515 cc05f685f98ea0b4a3c0b513b6886001 389 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 268 288 - T 29-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 SMALA_RS38515 cc05f685f98ea0b4a3c0b513b6886001 389 SUPERFAMILY SSF56796 18 387 2.22E-108 T 29-03-2018 SMALA_RS38515 cc05f685f98ea0b4a3c0b513b6886001 389 Gene3D G3DSA:1.20.1090.10 194 389 2.1E-51 T 29-03-2018 SMALA_RS04595 51fdff73d853f33bb12bb09b755f64e9 584 SUPERFAMILY SSF161098 78 262 8.37E-36 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS04595 51fdff73d853f33bb12bb09b755f64e9 584 Gene3D G3DSA:1.10.3720.10 338 584 4.7E-26 T 29-03-2018 SMALA_RS04595 51fdff73d853f33bb12bb09b755f64e9 584 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 412 578 2.7E-16 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS04595 51fdff73d853f33bb12bb09b755f64e9 584 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 103 271 3.7E-18 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS04595 51fdff73d853f33bb12bb09b755f64e9 584 Gene3D G3DSA:1.10.3720.10 13 266 1.1E-29 T 29-03-2018 SMALA_RS04595 51fdff73d853f33bb12bb09b755f64e9 584 TIGRFAM TIGR01097 PhnE: phosphonate ABC transporter, permease protein PhnE 31 274 6.3E-68 T 29-03-2018 IPR005769 ABC transporter, permease PhnE/PtxC GO:0005887|GO:0015604|GO:0015716 SMALA_RS04595 51fdff73d853f33bb12bb09b755f64e9 584 TIGRFAM TIGR01097 PhnE: phosphonate ABC transporter, permease protein PhnE 336 583 4.5E-68 T 29-03-2018 IPR005769 ABC transporter, permease PhnE/PtxC GO:0005887|GO:0015604|GO:0015716 SMALA_RS04595 51fdff73d853f33bb12bb09b755f64e9 584 SUPERFAMILY SSF161098 387 573 7.85E-33 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS18105 48a76416f44a097d3bfb5ba9ce689424 166 Pfam PF11377 Protein of unknown function (DUF3180) 9 150 1.7E-34 T 29-03-2018 IPR021517 Protein of unknown function DUF3180 SMALA_RS22495 23dd161ccf6b82509ab97fb03faadb08 240 SUPERFAMILY SSF46785 160 237 2.97E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS22495 23dd161ccf6b82509ab97fb03faadb08 240 Pfam PF00027 Cyclic nucleotide-binding domain 45 128 6.4E-17 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain SMALA_RS22495 23dd161ccf6b82509ab97fb03faadb08 240 SMART SM00419 181 229 4.0E-8 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 SMALA_RS22495 23dd161ccf6b82509ab97fb03faadb08 240 Gene3D G3DSA:2.60.120.10 20 157 1.9E-25 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SMALA_RS22495 23dd161ccf6b82509ab97fb03faadb08 240 SUPERFAMILY SSF51206 20 155 2.23E-27 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like SMALA_RS22495 23dd161ccf6b82509ab97fb03faadb08 240 Pfam PF13545 Crp-like helix-turn-helix domain 162 235 3.5E-13 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 SMALA_RS22495 23dd161ccf6b82509ab97fb03faadb08 240 SMART SM00100 24 142 2.8E-19 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain SMALA_RS22495 23dd161ccf6b82509ab97fb03faadb08 240 Gene3D G3DSA:1.10.10.10 158 238 6.2E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS22495 23dd161ccf6b82509ab97fb03faadb08 240 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 187 203 2.6E-5 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 SMALA_RS22495 23dd161ccf6b82509ab97fb03faadb08 240 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 203 218 2.6E-5 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 SMALA_RS27970 53872fb11b6b3e6a911894d7cd5e2084 322 SUPERFAMILY SSF56042 148 294 8.2E-34 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain SMALA_RS27970 53872fb11b6b3e6a911894d7cd5e2084 322 Gene3D G3DSA:3.90.650.10 151 315 2.8E-44 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain SMALA_RS27970 53872fb11b6b3e6a911894d7cd5e2084 322 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 9 315 5.7E-85 T 29-03-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 SMALA_RS27970 53872fb11b6b3e6a911894d7cd5e2084 322 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 8 312 28.835 T 29-03-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 SMALA_RS27970 53872fb11b6b3e6a911894d7cd5e2084 322 Gene3D G3DSA:3.30.1330.10 1 148 1.1E-37 T 29-03-2018 IPR016188 PurM-like, N-terminal domain SMALA_RS27970 53872fb11b6b3e6a911894d7cd5e2084 322 Pfam PF02769 AIR synthase related protein, C-terminal domain 156 246 4.8E-6 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain SMALA_RS27970 53872fb11b6b3e6a911894d7cd5e2084 322 SUPERFAMILY SSF55326 5 142 7.33E-35 T 29-03-2018 IPR016188 PurM-like, N-terminal domain SMALA_RS27970 53872fb11b6b3e6a911894d7cd5e2084 322 PIRSF PIRSF005303 3 315 3.1E-91 T 29-03-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 SMALA_RS27970 53872fb11b6b3e6a911894d7cd5e2084 322 Pfam PF00586 AIR synthase related protein, N-terminal domain 33 142 9.4E-22 T 29-03-2018 IPR016188 PurM-like, N-terminal domain SMALA_RS12385 2f82c3356a53ef9703a19d27af2d929d 328 Hamap MF_01962 Adenine deaminase. 3 312 80.596 T 29-03-2018 IPR028892 Adenine deaminase type 2 GO:0000034|GO:0006146 KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 SMALA_RS12385 2f82c3356a53ef9703a19d27af2d929d 328 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 5 323 3.6E-115 T 29-03-2018 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 SMALA_RS12385 2f82c3356a53ef9703a19d27af2d929d 328 SUPERFAMILY SSF51556 5 317 1.02E-82 T 29-03-2018 IPR032466 Metal-dependent hydrolase SMALA_RS12385 2f82c3356a53ef9703a19d27af2d929d 328 Gene3D G3DSA:3.20.20.140 2 328 3.8E-80 T 29-03-2018 SMALA_RS12385 2f82c3356a53ef9703a19d27af2d929d 328 Pfam PF00962 Adenosine/AMP deaminase 4 320 1.1E-72 T 29-03-2018 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 SMALA_RS28055 23f4ebc3c4b0ce4f3b9c95931218fcd2 472 Gene3D G3DSA:1.20.1250.20 249 472 8.0E-35 T 29-03-2018 SMALA_RS28055 23f4ebc3c4b0ce4f3b9c95931218fcd2 472 Pfam PF00083 Sugar (and other) transporter 27 471 5.5E-105 T 29-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 SMALA_RS28055 23f4ebc3c4b0ce4f3b9c95931218fcd2 472 Gene3D G3DSA:1.20.1250.20 21 228 1.3E-32 T 29-03-2018 SMALA_RS28055 23f4ebc3c4b0ce4f3b9c95931218fcd2 472 PRINTS PR00171 Sugar transporter signature 377 398 7.0E-23 T 29-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 SMALA_RS28055 23f4ebc3c4b0ce4f3b9c95931218fcd2 472 PRINTS PR00171 Sugar transporter signature 34 44 7.0E-23 T 29-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 SMALA_RS28055 23f4ebc3c4b0ce4f3b9c95931218fcd2 472 PRINTS PR00171 Sugar transporter signature 400 412 7.0E-23 T 29-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 SMALA_RS28055 23f4ebc3c4b0ce4f3b9c95931218fcd2 472 PRINTS PR00171 Sugar transporter signature 117 136 7.0E-23 T 29-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 SMALA_RS28055 23f4ebc3c4b0ce4f3b9c95931218fcd2 472 PRINTS PR00171 Sugar transporter signature 284 294 7.0E-23 T 29-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 SMALA_RS28055 23f4ebc3c4b0ce4f3b9c95931218fcd2 472 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 21 471 8.9E-101 T 29-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 SMALA_RS28055 23f4ebc3c4b0ce4f3b9c95931218fcd2 472 ProSitePatterns PS00217 Sugar transport proteins signature 2. 122 147 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMALA_RS28055 23f4ebc3c4b0ce4f3b9c95931218fcd2 472 ProSitePatterns PS00216 Sugar transport proteins signature 1. 328 345 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMALA_RS28055 23f4ebc3c4b0ce4f3b9c95931218fcd2 472 SUPERFAMILY SSF103473 22 471 1.96E-72 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS04175 9b507cbdda1425b7b37e59477369bf07 139 SUPERFAMILY SSF81301 21 127 9.15E-6 T 29-03-2018 SMALA_RS20560 c5d14a248dbc4309cb8accbf916eb414 176 Gene3D G3DSA:3.10.180.10 10 160 2.0E-18 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS20560 c5d14a248dbc4309cb8accbf916eb414 176 SUPERFAMILY SSF54593 19 138 1.06E-20 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS20560 c5d14a248dbc4309cb8accbf916eb414 176 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 20 133 4.0E-13 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMALA_RS12980 6f7867a7c95ae6a7ef8e2eb27636ae0d 629 Gene3D G3DSA:3.40.50.980 11 209 2.2E-38 T 29-03-2018 SMALA_RS12980 6f7867a7c95ae6a7ef8e2eb27636ae0d 629 Gene3D G3DSA:3.40.50.980 210 414 3.4E-35 T 29-03-2018 SMALA_RS12980 6f7867a7c95ae6a7ef8e2eb27636ae0d 629 Pfam PF00501 AMP-binding enzyme 21 493 3.7E-93 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS12980 6f7867a7c95ae6a7ef8e2eb27636ae0d 629 ProSitePatterns PS00455 Putative AMP-binding domain signature. 204 215 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS12980 6f7867a7c95ae6a7ef8e2eb27636ae0d 629 SUPERFAMILY SSF56801 9 307 6.93E-114 T 29-03-2018 SMALA_RS12980 6f7867a7c95ae6a7ef8e2eb27636ae0d 629 SUPERFAMILY SSF56801 364 624 6.93E-114 T 29-03-2018 SMALA_RS12980 6f7867a7c95ae6a7ef8e2eb27636ae0d 629 Gene3D G3DSA:2.30.38.10 415 486 2.1E-19 T 29-03-2018 SMALA_RS12980 6f7867a7c95ae6a7ef8e2eb27636ae0d 629 Gene3D G3DSA:3.30.300.30 488 625 1.4E-14 T 29-03-2018 SMALA_RS25720 ae999a414aa3883350d4f70354c8a660 305 Gene3D G3DSA:3.40.50.300 3 250 2.0E-60 T 29-03-2018 SMALA_RS25720 ae999a414aa3883350d4f70354c8a660 305 Pfam PF00005 ABC transporter 23 158 3.6E-26 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS25720 ae999a414aa3883350d4f70354c8a660 305 SMART SM00382 31 207 1.7E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS25720 ae999a414aa3883350d4f70354c8a660 305 SUPERFAMILY SSF52540 5 219 5.13E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS37290 75d703f2541edd20b1c84cb534737de0 129 Gene3D G3DSA:3.10.290.10 1 98 1.5E-19 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SMALA_RS37290 75d703f2541edd20b1c84cb534737de0 129 SMART SM00363 8 75 4.3E-9 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SMALA_RS37290 75d703f2541edd20b1c84cb534737de0 129 Pfam PF01479 S4 domain 8 54 2.0E-12 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SMALA_RS37290 75d703f2541edd20b1c84cb534737de0 129 SUPERFAMILY SSF55174 7 90 1.31E-21 T 29-03-2018 SMALA_RS37290 75d703f2541edd20b1c84cb534737de0 129 PIRSF PIRSF016821 5 126 3.8E-45 T 29-03-2018 IPR025708 Heat shock protein 15 GO:0003677|GO:0003727|GO:0034605|GO:0043023 SMALA_RS26360 4eb7a5f1d1e3563b625e5f8f6031b362 86 Gene3D G3DSA:3.30.40.10 1 86 1.1E-19 T 29-03-2018 IPR013083 Zinc finger, RING/FYVE/PHD-type SMALA_RS26360 4eb7a5f1d1e3563b625e5f8f6031b362 86 Pfam PF02148 Zn-finger in ubiquitin-hydrolases and other protein 37 83 2.1E-11 T 29-03-2018 IPR001607 Zinc finger, UBP-type GO:0008270 SMALA_RS26360 4eb7a5f1d1e3563b625e5f8f6031b362 86 SUPERFAMILY SSF57850 3 85 2.12E-25 T 29-03-2018 SMALA_RS32555 c611e751ba13ace8fe62ae2811b178b7 215 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 7 178 1.3E-20 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMALA_RS32555 c611e751ba13ace8fe62ae2811b178b7 215 Gene3D G3DSA:1.10.150.240 22 72 8.2E-10 T 29-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 SMALA_RS32555 c611e751ba13ace8fe62ae2811b178b7 215 Gene3D G3DSA:3.40.50.1000 73 203 1.9E-26 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS32555 c611e751ba13ace8fe62ae2811b178b7 215 Pfam PF13419 Haloacid dehalogenase-like hydrolase 8 178 2.4E-19 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS32555 c611e751ba13ace8fe62ae2811b178b7 215 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 85 154 7.5E-6 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMALA_RS32555 c611e751ba13ace8fe62ae2811b178b7 215 SUPERFAMILY SSF56784 6 199 8.71E-46 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS21460 752c30fabcca1f9b3b120257e4ba46cb 321 Pfam PF01571 Aminomethyltransferase folate-binding domain 22 141 8.3E-18 T 29-03-2018 IPR006222 Glycine cleavage T-protein-like, N-terminal SMALA_RS21460 752c30fabcca1f9b3b120257e4ba46cb 321 Gene3D G3DSA:3.30.70.1400 47 237 1.1E-32 T 29-03-2018 SMALA_RS21460 752c30fabcca1f9b3b120257e4ba46cb 321 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 224 298 3.0E-9 T 29-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 SMALA_RS21460 752c30fabcca1f9b3b120257e4ba46cb 321 Gene3D G3DSA:2.40.30.110 239 318 4.9E-13 T 29-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 SMALA_RS21460 752c30fabcca1f9b3b120257e4ba46cb 321 SUPERFAMILY SSF101790 243 309 9.81E-5 T 29-03-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain SMALA_RS21460 752c30fabcca1f9b3b120257e4ba46cb 321 PIRSF PIRSF006487 18 156 3.4E-12 T 29-03-2018 SMALA_RS21460 752c30fabcca1f9b3b120257e4ba46cb 321 PIRSF PIRSF006487 164 319 1.0E-8 T 29-03-2018 SMALA_RS21460 752c30fabcca1f9b3b120257e4ba46cb 321 TIGRFAM TIGR03317 ygfZ_signature: folate-binding protein YgfZ 186 250 2.7E-21 T 29-03-2018 IPR017703 YgfZ/GcvT conserved site SMALA_RS21460 752c30fabcca1f9b3b120257e4ba46cb 321 SUPERFAMILY SSF103025 22 240 2.83E-54 T 29-03-2018 SMALA_RS01630 64af4fd35b72bddbcec53b89ac951556 513 Gene3D G3DSA:2.30.38.10 337 410 9.6E-22 T 29-03-2018 SMALA_RS01630 64af4fd35b72bddbcec53b89ac951556 513 Gene3D G3DSA:3.40.50.980 180 333 5.8E-35 T 29-03-2018 SMALA_RS01630 64af4fd35b72bddbcec53b89ac951556 513 Gene3D G3DSA:3.40.50.980 5 179 2.8E-24 T 29-03-2018 SMALA_RS01630 64af4fd35b72bddbcec53b89ac951556 513 ProSitePatterns PS00455 Putative AMP-binding domain signature. 175 186 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS01630 64af4fd35b72bddbcec53b89ac951556 513 Pfam PF00501 AMP-binding enzyme 16 416 1.6E-68 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS01630 64af4fd35b72bddbcec53b89ac951556 513 Pfam PF13193 AMP-binding enzyme C-terminal domain 426 500 2.7E-15 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS01630 64af4fd35b72bddbcec53b89ac951556 513 Gene3D G3DSA:3.30.300.30 411 512 2.0E-21 T 29-03-2018 SMALA_RS01630 64af4fd35b72bddbcec53b89ac951556 513 SUPERFAMILY SSF56801 7 509 6.02E-110 T 29-03-2018 SMALA_RS41320 31ec0d56305d9054b5ab359fc3db0bf1 259 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS41320 31ec0d56305d9054b5ab359fc3db0bf1 259 SMART SM00382 30 221 5.4E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS41320 31ec0d56305d9054b5ab359fc3db0bf1 259 Pfam PF00005 ABC transporter 21 173 2.3E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS41320 31ec0d56305d9054b5ab359fc3db0bf1 259 SUPERFAMILY SSF52540 4 231 1.71E-54 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS41320 31ec0d56305d9054b5ab359fc3db0bf1 259 Gene3D G3DSA:3.40.50.300 1 243 1.3E-51 T 29-03-2018 SMALA_RS38405 39eeb8ae40de685b6367de2113f566df 348 Pfam PF14716 Helix-hairpin-helix domain 5 69 8.2E-12 T 29-03-2018 IPR010996 DNA polymerase beta-like, N-terminal domain SMALA_RS38405 39eeb8ae40de685b6367de2113f566df 348 SMART SM00481 104 183 5.4E-16 T 29-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal SMALA_RS38405 39eeb8ae40de685b6367de2113f566df 348 Gene3D G3DSA:1.10.150.110 2 83 1.2E-12 T 29-03-2018 SMALA_RS38405 39eeb8ae40de685b6367de2113f566df 348 Pfam PF02811 PHP domain 105 191 4.6E-6 T 29-03-2018 IPR004013 PHP domain GO:0003824 SMALA_RS38405 39eeb8ae40de685b6367de2113f566df 348 Gene3D G3DSA:3.20.20.140 104 332 2.1E-47 T 29-03-2018 SMALA_RS38405 39eeb8ae40de685b6367de2113f566df 348 SUPERFAMILY SSF47802 3 82 7.06E-11 T 29-03-2018 IPR010996 DNA polymerase beta-like, N-terminal domain SMALA_RS38405 39eeb8ae40de685b6367de2113f566df 348 SUPERFAMILY SSF89550 103 335 2.22E-46 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 SMALA_RS38405 39eeb8ae40de685b6367de2113f566df 348 PIRSF PIRSF036978 1 339 2.3E-168 T 29-03-2018 IPR017078 Uncharacterised conserved protein UCP036978, histidinol phosphatase-related hydrolase, SCO0789 SMALA_RS18305 6c9c32dccc029de31473cbc7a115d5df 229 ProSitePatterns PS00622 LuxR-type HTH domain signature. 174 201 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS18305 6c9c32dccc029de31473cbc7a115d5df 229 Pfam PF00196 Bacterial regulatory proteins, luxR family 159 213 5.2E-18 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS18305 6c9c32dccc029de31473cbc7a115d5df 229 Gene3D G3DSA:3.40.50.2300 7 132 4.4E-29 T 29-03-2018 SMALA_RS18305 6c9c32dccc029de31473cbc7a115d5df 229 SMART SM00421 157 214 2.1E-23 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS18305 6c9c32dccc029de31473cbc7a115d5df 229 SMART SM00448 8 121 5.9E-23 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS18305 6c9c32dccc029de31473cbc7a115d5df 229 SUPERFAMILY SSF46894 148 219 4.08E-21 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS18305 6c9c32dccc029de31473cbc7a115d5df 229 SUPERFAMILY SSF52172 9 132 2.56E-28 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS18305 6c9c32dccc029de31473cbc7a115d5df 229 Gene3D G3DSA:1.10.10.10 133 223 2.0E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS18305 6c9c32dccc029de31473cbc7a115d5df 229 Pfam PF00072 Response regulator receiver domain 10 121 2.2E-21 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS18305 6c9c32dccc029de31473cbc7a115d5df 229 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 160 174 3.3E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS18305 6c9c32dccc029de31473cbc7a115d5df 229 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 190 202 3.3E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS18305 6c9c32dccc029de31473cbc7a115d5df 229 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 174 190 3.3E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS07005 9aea4fee6f378ef88e3fced7e8567d7d 222 Pfam PF06283 Trehalose utilisation 3 217 7.2E-41 T 29-03-2018 IPR029010 ThuA-like domain SMALA_RS07005 9aea4fee6f378ef88e3fced7e8567d7d 222 SUPERFAMILY SSF52317 3 220 1.79E-37 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS07005 9aea4fee6f378ef88e3fced7e8567d7d 222 Gene3D G3DSA:3.40.50.880 8 222 1.7E-34 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS33795 145e561c9191c8d1f9b639461f9f8698 533 SUPERFAMILY SSF56601 232 532 4.44E-51 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMALA_RS33795 145e561c9191c8d1f9b639461f9f8698 533 Gene3D G3DSA:3.40.710.10 231 532 1.9E-58 T 29-03-2018 SMALA_RS33795 145e561c9191c8d1f9b639461f9f8698 533 Pfam PF00905 Penicillin binding protein transpeptidase domain 257 531 1.1E-37 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 SMALA_RS20985 8719c9ee305ca93448d1113f4d58f487 267 Gene3D G3DSA:3.90.1200.10 42 267 3.1E-8 T 29-03-2018 SMALA_RS20985 8719c9ee305ca93448d1113f4d58f487 267 Pfam PF01636 Phosphotransferase enzyme family 134 221 4.8E-5 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase SMALA_RS20985 8719c9ee305ca93448d1113f4d58f487 267 SUPERFAMILY SSF56112 27 207 1.41E-14 T 29-03-2018 IPR011009 Protein kinase-like domain SMALA_RS32495 0a6988ba96ee4b2da7ae7be93a5223e3 286 SUPERFAMILY SSF56219 35 281 1.7E-36 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMALA_RS32495 0a6988ba96ee4b2da7ae7be93a5223e3 286 Gene3D G3DSA:3.60.10.10 28 278 1.6E-37 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMALA_RS32495 0a6988ba96ee4b2da7ae7be93a5223e3 286 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 44 270 8.5E-16 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMALA_RS41420 b6404a80ececc30b913cccbf6604b744 404 ProSitePatterns PS01043 Transposases, IS30 family, signature. 346 362 - T 29-03-2018 IPR001598 Transposase, IS30, conserved site GO:0003677|GO:0004803|GO:0006313 SMALA_RS41420 b6404a80ececc30b913cccbf6604b744 404 Pfam PF13936 Helix-turn-helix domain 78 119 3.9E-14 T 29-03-2018 IPR025246 Transposase IS30-like HTH domain SMALA_RS41420 b6404a80ececc30b913cccbf6604b744 404 Gene3D G3DSA:1.10.10.60 133 197 0.2 T 29-03-2018 SMALA_RS41420 b6404a80ececc30b913cccbf6604b744 404 Gene3D G3DSA:1.10.10.10 74 132 1.6E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS41420 b6404a80ececc30b913cccbf6604b744 404 SUPERFAMILY SSF46689 77 179 3.11E-6 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS41420 b6404a80ececc30b913cccbf6604b744 404 Pfam PF00665 Integrase core domain 253 359 2.2E-12 T 29-03-2018 IPR001584 Integrase, catalytic core GO:0015074 SMALA_RS41420 b6404a80ececc30b913cccbf6604b744 404 Gene3D G3DSA:3.30.420.10 244 404 2.4E-22 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SMALA_RS41420 b6404a80ececc30b913cccbf6604b744 404 SUPERFAMILY SSF53098 252 400 8.65E-25 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SMALA_RS41420 b6404a80ececc30b913cccbf6604b744 404 Gene3D G3DSA:1.10.10.10 18 66 4.2E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS10990 06571fe05b685ca4caafda7c0f1ff3c5 269 PIRSF PIRSF006648 2 269 1.2E-76 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMALA_RS10990 06571fe05b685ca4caafda7c0f1ff3c5 269 Pfam PF01061 ABC-2 type transporter 21 230 5.1E-32 T 29-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 SMALA_RS09620 70498b7b5840ff3c6a55554d23f44e77 320 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 256 269 - T 29-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 SMALA_RS09620 70498b7b5840ff3c6a55554d23f44e77 320 Gene3D G3DSA:3.40.1190.20 1 320 2.2E-58 T 29-03-2018 IPR029056 Ribokinase-like SMALA_RS09620 70498b7b5840ff3c6a55554d23f44e77 320 SUPERFAMILY SSF53613 2 315 5.3E-61 T 29-03-2018 IPR029056 Ribokinase-like SMALA_RS09620 70498b7b5840ff3c6a55554d23f44e77 320 Pfam PF00294 pfkB family carbohydrate kinase 2 313 4.5E-42 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB SMALA_RS04435 7d7239786983db79b46e9830fb176c94 493 SUPERFAMILY SSF75011 173 462 7.72E-8 T 29-03-2018 SMALA_RS04435 7d7239786983db79b46e9830fb176c94 493 Pfam PF08309 LVIVD repeat 92 127 0.0021 T 29-03-2018 IPR013211 LVIVD SMALA_RS04435 7d7239786983db79b46e9830fb176c94 493 Gene3D G3DSA:2.130.10.10 60 483 7.4E-5 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMALA_RS05660 175ae61b564ddf3351b6ad3f971b5683 224 SUPERFAMILY SSF56235 1 223 1.47E-58 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SMALA_RS05660 175ae61b564ddf3351b6ad3f971b5683 224 Gene3D G3DSA:3.60.20.10 1 216 2.4E-61 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SMALA_RS05660 175ae61b564ddf3351b6ad3f971b5683 224 Pfam PF06267 Family of unknown function (DUF1028) 2 191 1.5E-51 T 29-03-2018 IPR010430 Protein of unknown function DUF1028 SMALA_RS26215 986cb6a2d074049d6c7ef9a72d2713a1 340 SUPERFAMILY SSF47240 2 327 4.87E-88 T 29-03-2018 IPR009078 Ferritin-like superfamily SMALA_RS26215 986cb6a2d074049d6c7ef9a72d2713a1 340 Pfam PF00268 Ribonucleotide reductase, small chain 19 303 5.7E-82 T 29-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMALA_RS26215 986cb6a2d074049d6c7ef9a72d2713a1 340 Gene3D G3DSA:1.10.620.20 8 314 1.4E-92 T 29-03-2018 SMALA_RS26215 986cb6a2d074049d6c7ef9a72d2713a1 340 PIRSF PIRSF000355 3 339 1.7E-100 T 29-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMALA_RS37970 3b735aeaf33544a54f8feda0d2608fbb 334 SUPERFAMILY SSF55347 123 250 2.94E-25 T 29-03-2018 SMALA_RS37970 3b735aeaf33544a54f8feda0d2608fbb 334 Gene3D G3DSA:3.30.360.10 130 334 7.6E-39 T 29-03-2018 SMALA_RS37970 3b735aeaf33544a54f8feda0d2608fbb 334 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 131 233 2.7E-8 T 29-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 SMALA_RS37970 3b735aeaf33544a54f8feda0d2608fbb 334 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 1 118 2.3E-20 T 29-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 SMALA_RS37970 3b735aeaf33544a54f8feda0d2608fbb 334 Gene3D G3DSA:3.40.50.720 1 129 2.8E-33 T 29-03-2018 SMALA_RS37970 3b735aeaf33544a54f8feda0d2608fbb 334 SUPERFAMILY SSF51735 2 147 8.94E-39 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS08270 974d04acc799e7546f2a61051500cf83 235 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 50 73 2.7E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS08270 974d04acc799e7546f2a61051500cf83 235 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 42 2.7E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS08270 974d04acc799e7546f2a61051500cf83 235 Gene3D G3DSA:1.10.357.10 82 235 4.1E-9 T 29-03-2018 SMALA_RS08270 974d04acc799e7546f2a61051500cf83 235 Gene3D G3DSA:1.10.10.60 11 50 4.8E-13 T 29-03-2018 SMALA_RS08270 974d04acc799e7546f2a61051500cf83 235 Gene3D G3DSA:1.10.260.40 51 81 1.2E-9 T 29-03-2018 SMALA_RS08270 974d04acc799e7546f2a61051500cf83 235 SUPERFAMILY SSF46689 16 90 7.98E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS08270 974d04acc799e7546f2a61051500cf83 235 Pfam PF00440 Bacterial regulatory proteins, tetR family 29 75 1.1E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS40900 9f1be78bfa22fd4a9d321820aa6120b0 408 SUPERFAMILY SSF48264 13 402 1.31E-90 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS40900 9f1be78bfa22fd4a9d321820aa6120b0 408 PRINTS PR00359 B-class P450 signature 79 90 5.4E-40 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS40900 9f1be78bfa22fd4a9d321820aa6120b0 408 PRINTS PR00359 B-class P450 signature 285 312 5.4E-40 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS40900 9f1be78bfa22fd4a9d321820aa6120b0 408 PRINTS PR00359 B-class P450 signature 187 209 5.4E-40 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS40900 9f1be78bfa22fd4a9d321820aa6120b0 408 PRINTS PR00359 B-class P450 signature 126 142 5.4E-40 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS40900 9f1be78bfa22fd4a9d321820aa6120b0 408 PRINTS PR00359 B-class P450 signature 344 353 5.4E-40 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS40900 9f1be78bfa22fd4a9d321820aa6120b0 408 PRINTS PR00359 B-class P450 signature 353 364 5.4E-40 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS40900 9f1be78bfa22fd4a9d321820aa6120b0 408 PRINTS PR00359 B-class P450 signature 313 328 5.4E-40 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS40900 9f1be78bfa22fd4a9d321820aa6120b0 408 PRINTS PR00359 B-class P450 signature 143 158 5.4E-40 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS40900 9f1be78bfa22fd4a9d321820aa6120b0 408 PRINTS PR00359 B-class P450 signature 268 279 5.4E-40 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS40900 9f1be78bfa22fd4a9d321820aa6120b0 408 Pfam PF00067 Cytochrome P450 34 376 2.6E-34 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS40900 9f1be78bfa22fd4a9d321820aa6120b0 408 PRINTS PR00385 P450 superfamily signature 344 353 3.5E-5 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS40900 9f1be78bfa22fd4a9d321820aa6120b0 408 PRINTS PR00385 P450 superfamily signature 353 364 3.5E-5 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS40900 9f1be78bfa22fd4a9d321820aa6120b0 408 PRINTS PR00385 P450 superfamily signature 268 279 3.5E-5 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS40900 9f1be78bfa22fd4a9d321820aa6120b0 408 PRINTS PR00385 P450 superfamily signature 233 250 3.5E-5 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS40900 9f1be78bfa22fd4a9d321820aa6120b0 408 Gene3D G3DSA:1.10.630.10 7 405 6.2E-78 T 29-03-2018 SMALA_RS25235 99696b7b3eb8631946cae2f2bedef9f6 228 Pfam PF10014 2OG-Fe dioxygenase 22 205 1.3E-43 T 29-03-2018 IPR018724 2OG-Fe dioxygenase SMALA_RS05170 6654c5e723ffe3a89156ee32c33ece46 154 Pfam PF01638 HxlR-like helix-turn-helix 24 112 6.7E-19 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type SMALA_RS05170 6654c5e723ffe3a89156ee32c33ece46 154 Gene3D G3DSA:1.10.10.10 6 147 5.1E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS05170 6654c5e723ffe3a89156ee32c33ece46 154 SUPERFAMILY SSF46785 12 137 2.52E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS05680 14be090a07b2bf77db3b2a8525c97751 255 Gene3D G3DSA:3.40.50.1820 3 255 1.3E-28 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS05680 14be090a07b2bf77db3b2a8525c97751 255 SUPERFAMILY SSF53474 7 251 6.93E-32 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS05680 14be090a07b2bf77db3b2a8525c97751 255 Pfam PF12697 Alpha/beta hydrolase family 22 245 6.4E-22 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS43020 daebed52cbb38f6b1a4e2e240fc54573 269 Pfam PF01609 Transposase DDE domain 101 259 3.8E-20 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 SMALA_RS43020 daebed52cbb38f6b1a4e2e240fc54573 269 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 7 85 4.3E-21 T 29-03-2018 IPR025161 Putative transposase IS4/IS5 family SMALA_RS07290 2fd0d72b12e13b5d7ed36f01116e704d 310 SUPERFAMILY SSF52980 67 227 4.4E-10 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 SMALA_RS07290 2fd0d72b12e13b5d7ed36f01116e704d 310 Pfam PF12705 PD-(D/E)XK nuclease superfamily 41 292 5.4E-36 T 29-03-2018 SMALA_RS07290 2fd0d72b12e13b5d7ed36f01116e704d 310 Gene3D G3DSA:3.90.320.10 16 234 9.6E-30 T 29-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 SMALA_RS18360 07b07bc03086f8ffd9ac2bf74245a8a1 125 Gene3D G3DSA:1.10.10.10 25 110 4.3E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS18360 07b07bc03086f8ffd9ac2bf74245a8a1 125 Pfam PF12840 Helix-turn-helix domain 35 91 1.3E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS18360 07b07bc03086f8ffd9ac2bf74245a8a1 125 SMART SM00418 35 115 2.9E-6 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS18360 07b07bc03086f8ffd9ac2bf74245a8a1 125 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 71 86 9.9E-7 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS18360 07b07bc03086f8ffd9ac2bf74245a8a1 125 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 37 52 9.9E-7 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS18360 07b07bc03086f8ffd9ac2bf74245a8a1 125 SUPERFAMILY SSF46785 24 117 5.93E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS37300 d863a6f8eba89b283401b0c6e2f4ef82 886 SUPERFAMILY SSF81606 548 747 7.32E-9 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS37300 d863a6f8eba89b283401b0c6e2f4ef82 886 Gene3D G3DSA:3.30.450.40 328 505 1.5E-30 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS37300 d863a6f8eba89b283401b0c6e2f4ef82 886 SMART SM00331 530 748 8.7E-38 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS37300 d863a6f8eba89b283401b0c6e2f4ef82 886 Pfam PF13581 Histidine kinase-like ATPase domain 761 867 2.8E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS37300 d863a6f8eba89b283401b0c6e2f4ef82 886 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 558 748 6.8E-51 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS37300 d863a6f8eba89b283401b0c6e2f4ef82 886 Pfam PF17203 Single cache domain 3 44 170 9.6E-24 T 29-03-2018 IPR033463 Single cache domain 3 SMALA_RS37300 d863a6f8eba89b283401b0c6e2f4ef82 886 Pfam PF13185 GAF domain 435 503 1.9E-9 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS37300 d863a6f8eba89b283401b0c6e2f4ef82 886 Gene3D G3DSA:3.30.450.20 34 167 2.4E-24 T 29-03-2018 SMALA_RS37300 d863a6f8eba89b283401b0c6e2f4ef82 886 SUPERFAMILY SSF55781 401 506 2.16E-13 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS37300 d863a6f8eba89b283401b0c6e2f4ef82 886 Gene3D G3DSA:3.60.40.10 506 751 1.8E-42 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS37300 d863a6f8eba89b283401b0c6e2f4ef82 886 SMART SM00065 330 512 1.4E-4 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS37300 d863a6f8eba89b283401b0c6e2f4ef82 886 Gene3D G3DSA:3.30.565.10 752 877 6.1E-11 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS37300 d863a6f8eba89b283401b0c6e2f4ef82 886 Gene3D G3DSA:3.30.450.20 198 327 1.6E-10 T 29-03-2018 SMALA_RS37300 d863a6f8eba89b283401b0c6e2f4ef82 886 SUPERFAMILY SSF103190 42 171 2.16E-32 T 29-03-2018 IPR029151 Periplasmic sensor domain-like SMALA_RS39260 b61e79e9f24267a5281b5183cd1058b9 542 Gene3D G3DSA:3.30.559.10 11 210 3.8E-28 T 29-03-2018 SMALA_RS39260 b61e79e9f24267a5281b5183cd1058b9 542 SUPERFAMILY SSF47336 461 531 3.4E-15 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS39260 b61e79e9f24267a5281b5183cd1058b9 542 Gene3D G3DSA:1.10.1200.10 450 539 1.0E-18 T 29-03-2018 SMALA_RS39260 b61e79e9f24267a5281b5183cd1058b9 542 Pfam PF00668 Condensation domain 23 435 2.3E-57 T 29-03-2018 IPR001242 Condensation domain SMALA_RS39260 b61e79e9f24267a5281b5183cd1058b9 542 Pfam PF00550 Phosphopantetheine attachment site 469 529 1.2E-9 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS39260 b61e79e9f24267a5281b5183cd1058b9 542 SUPERFAMILY SSF52777 211 432 1.78E-35 T 29-03-2018 SMALA_RS39260 b61e79e9f24267a5281b5183cd1058b9 542 SUPERFAMILY SSF52777 25 201 7.34E-33 T 29-03-2018 SMALA_RS39260 b61e79e9f24267a5281b5183cd1058b9 542 ProSitePatterns PS00012 Phosphopantetheine attachment site. 491 506 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS21545 919f9f119a2c8187b89d396aaef5faf4 473 Gene3D G3DSA:1.10.287.130 235 312 8.5E-13 T 29-03-2018 SMALA_RS21545 919f9f119a2c8187b89d396aaef5faf4 473 Pfam PF00512 His Kinase A (phospho-acceptor) domain 246 315 4.4E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS21545 919f9f119a2c8187b89d396aaef5faf4 473 SMART SM00388 245 316 3.9E-10 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS21545 919f9f119a2c8187b89d396aaef5faf4 473 SMART SM00304 191 244 5.6E-12 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMALA_RS21545 919f9f119a2c8187b89d396aaef5faf4 473 SMART SM00387 358 464 2.0E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS21545 919f9f119a2c8187b89d396aaef5faf4 473 Pfam PF00672 HAMP domain 191 239 1.7E-10 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMALA_RS21545 919f9f119a2c8187b89d396aaef5faf4 473 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 361 461 6.9E-23 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS21545 919f9f119a2c8187b89d396aaef5faf4 473 PRINTS PR00344 Bacterial sensor protein C-terminal signature 448 461 9.7E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS21545 919f9f119a2c8187b89d396aaef5faf4 473 PRINTS PR00344 Bacterial sensor protein C-terminal signature 391 405 9.7E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS21545 919f9f119a2c8187b89d396aaef5faf4 473 PRINTS PR00344 Bacterial sensor protein C-terminal signature 424 442 9.7E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS21545 919f9f119a2c8187b89d396aaef5faf4 473 PRINTS PR00344 Bacterial sensor protein C-terminal signature 409 419 9.7E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS21545 919f9f119a2c8187b89d396aaef5faf4 473 SUPERFAMILY SSF47384 228 315 6.67E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS21545 919f9f119a2c8187b89d396aaef5faf4 473 SUPERFAMILY SSF55874 306 462 3.54E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS21545 919f9f119a2c8187b89d396aaef5faf4 473 Gene3D G3DSA:3.30.565.10 322 468 3.9E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS21545 919f9f119a2c8187b89d396aaef5faf4 473 SUPERFAMILY SSF158472 194 241 4.05E-7 T 29-03-2018 SMALA_RS17490 55e91b6db46740c3a76576bb23afb8b7 309 Pfam PF01380 SIS domain 148 277 7.5E-22 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 SMALA_RS17490 55e91b6db46740c3a76576bb23afb8b7 309 SUPERFAMILY SSF46689 24 94 6.99E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS17490 55e91b6db46740c3a76576bb23afb8b7 309 Gene3D G3DSA:1.10.10.10 20 116 5.2E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS17490 55e91b6db46740c3a76576bb23afb8b7 309 Pfam PF01418 Helix-turn-helix domain, rpiR family 22 95 6.8E-13 T 29-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 SMALA_RS17490 55e91b6db46740c3a76576bb23afb8b7 309 SUPERFAMILY SSF53697 116 298 2.78E-40 T 29-03-2018 SMALA_RS17490 55e91b6db46740c3a76576bb23afb8b7 309 Gene3D G3DSA:3.40.50.10490 117 303 2.7E-39 T 29-03-2018 SMALA_RS16185 8ccfc7739137c8ebebfe0a77f5cc83f4 436 Pfam PF02353 Mycolic acid cyclopropane synthetase 143 415 9.2E-95 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS16185 8ccfc7739137c8ebebfe0a77f5cc83f4 436 Gene3D G3DSA:3.40.50.150 142 419 1.7E-67 T 29-03-2018 SMALA_RS16185 8ccfc7739137c8ebebfe0a77f5cc83f4 436 PIRSF PIRSF003085 5 436 1.1E-131 T 29-03-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 SMALA_RS16185 8ccfc7739137c8ebebfe0a77f5cc83f4 436 SMART SM00828 Methyltransferase in polyketide synthase (PKS) enzymes. 162 403 0.0015 T 29-03-2018 IPR020803 Polyketide synthase, methyltransferase domain SMALA_RS16185 8ccfc7739137c8ebebfe0a77f5cc83f4 436 SUPERFAMILY SSF53335 153 419 9.97E-80 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS04135 e69e7a68059c0e0e2441d02a96911f3e 334 Gene3D G3DSA:3.40.50.720 2 333 1.2E-51 T 29-03-2018 SMALA_RS04135 e69e7a68059c0e0e2441d02a96911f3e 334 Pfam PF01370 NAD dependent epimerase/dehydratase family 5 241 1.7E-23 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 SMALA_RS04135 e69e7a68059c0e0e2441d02a96911f3e 334 SUPERFAMILY SSF51735 2 327 2.18E-61 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS31490 41209f3affabc99d9cafc04cc1ecf970 453 ProSitePatterns PS00216 Sugar transport proteins signature 1. 90 106 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMALA_RS31490 41209f3affabc99d9cafc04cc1ecf970 453 Gene3D G3DSA:1.20.1250.20 25 228 2.0E-30 T 29-03-2018 SMALA_RS31490 41209f3affabc99d9cafc04cc1ecf970 453 Gene3D G3DSA:1.20.1250.20 250 453 8.9E-24 T 29-03-2018 SMALA_RS31490 41209f3affabc99d9cafc04cc1ecf970 453 ProSitePatterns PS00217 Sugar transport proteins signature 2. 132 157 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMALA_RS31490 41209f3affabc99d9cafc04cc1ecf970 453 SUPERFAMILY SSF103473 16 452 1.44E-71 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS31490 41209f3affabc99d9cafc04cc1ecf970 453 Pfam PF00083 Sugar (and other) transporter 70 451 1.1E-36 T 29-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 SMALA_RS29890 c6ad0a82ce92474cc795c34d0ce97efa 238 SUPERFAMILY SSF54909 18 237 1.61E-75 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel SMALA_RS29890 c6ad0a82ce92474cc795c34d0ce97efa 238 Gene3D G3DSA:3.30.70.1030 17 135 4.3E-41 T 29-03-2018 SMALA_RS29890 c6ad0a82ce92474cc795c34d0ce97efa 238 Gene3D G3DSA:3.30.70.1100 136 235 3.8E-29 T 29-03-2018 SMALA_RS29890 c6ad0a82ce92474cc795c34d0ce97efa 238 Pfam PF06778 Chlorite dismutase 40 227 1.3E-73 T 29-03-2018 IPR010644 Putative heme-dependent peroxidase/Chlorite dismutase SMALA_RS25900 60ec20a3481daf6f2261e00af9025adb 309 Gene3D G3DSA:3.40.50.1010 29 203 4.3E-19 T 29-03-2018 IPR029060 PIN domain-like SMALA_RS25900 60ec20a3481daf6f2261e00af9025adb 309 Pfam PF01936 NYN domain 41 187 2.6E-9 T 29-03-2018 IPR021139 NYN domain, limkain-b1-type SMALA_RS05495 ab6d2d402edd969eba4f6258641a973d 191 Gene3D G3DSA:1.10.10.60 2 35 1.0E-12 T 29-03-2018 SMALA_RS05495 ab6d2d402edd969eba4f6258641a973d 191 Gene3D G3DSA:1.10.260.40 36 62 2.5E-10 T 29-03-2018 SMALA_RS05495 ab6d2d402edd969eba4f6258641a973d 191 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 60 3.2E-13 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS05495 ab6d2d402edd969eba4f6258641a973d 191 Gene3D G3DSA:1.10.357.10 63 189 2.3E-4 T 29-03-2018 SMALA_RS05495 ab6d2d402edd969eba4f6258641a973d 191 SUPERFAMILY SSF46689 5 81 5.64E-18 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS05495 ab6d2d402edd969eba4f6258641a973d 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 3.0E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS05495 ab6d2d402edd969eba4f6258641a973d 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 3.0E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS08050 230f9030a870aa1de51d489b2c85f525 340 Pfam PF01341 Glycosyl hydrolases family 6 50 318 6.9E-83 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMALA_RS08050 230f9030a870aa1de51d489b2c85f525 340 ProSitePatterns PS00655 Glycosyl hydrolases family 6 signature 1. 107 123 - T 29-03-2018 IPR001524 Glycoside hydrolase, family 6, conserved site GO:0004553|GO:0005975 SMALA_RS08050 230f9030a870aa1de51d489b2c85f525 340 PRINTS PR00733 Glycosyl hydrolase family 6 signature 102 115 1.3E-39 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMALA_RS08050 230f9030a870aa1de51d489b2c85f525 340 PRINTS PR00733 Glycosyl hydrolase family 6 signature 218 228 1.3E-39 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMALA_RS08050 230f9030a870aa1de51d489b2c85f525 340 PRINTS PR00733 Glycosyl hydrolase family 6 signature 130 145 1.3E-39 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMALA_RS08050 230f9030a870aa1de51d489b2c85f525 340 PRINTS PR00733 Glycosyl hydrolase family 6 signature 62 81 1.3E-39 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMALA_RS08050 230f9030a870aa1de51d489b2c85f525 340 PRINTS PR00733 Glycosyl hydrolase family 6 signature 275 295 1.3E-39 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMALA_RS08050 230f9030a870aa1de51d489b2c85f525 340 PRINTS PR00733 Glycosyl hydrolase family 6 signature 187 200 1.3E-39 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMALA_RS08050 230f9030a870aa1de51d489b2c85f525 340 PRINTS PR00733 Glycosyl hydrolase family 6 signature 248 261 1.3E-39 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMALA_RS08050 230f9030a870aa1de51d489b2c85f525 340 PRINTS PR00733 Glycosyl hydrolase family 6 signature 299 313 1.3E-39 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMALA_RS08050 230f9030a870aa1de51d489b2c85f525 340 PIRSF PIRSF001100 23 340 3.5E-99 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMALA_RS08050 230f9030a870aa1de51d489b2c85f525 340 Gene3D G3DSA:3.20.20.40 39 336 1.9E-99 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMALA_RS08050 230f9030a870aa1de51d489b2c85f525 340 SUPERFAMILY SSF51989 32 337 4.19E-86 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMALA_RS24580 b19ee83941c055ec33767990717eb031 451 Pfam PF00246 Zinc carboxypeptidase 142 426 7.8E-70 T 29-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 SMALA_RS24580 b19ee83941c055ec33767990717eb031 451 ProSitePatterns PS00133 Zinc carboxypeptidases, zinc-binding region 2 signature. 327 337 - T 29-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 SMALA_RS24580 b19ee83941c055ec33767990717eb031 451 SUPERFAMILY SSF53187 130 435 1.19E-84 T 29-03-2018 SMALA_RS24580 b19ee83941c055ec33767990717eb031 451 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 324 337 9.3E-13 T 29-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 SMALA_RS24580 b19ee83941c055ec33767990717eb031 451 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 158 170 9.3E-13 T 29-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 SMALA_RS24580 b19ee83941c055ec33767990717eb031 451 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 265 273 9.3E-13 T 29-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 SMALA_RS24580 b19ee83941c055ec33767990717eb031 451 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 183 197 9.3E-13 T 29-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 SMALA_RS24580 b19ee83941c055ec33767990717eb031 451 SMART SM00631 132 423 2.7E-98 T 29-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 SMALA_RS24580 b19ee83941c055ec33767990717eb031 451 Gene3D G3DSA:3.40.630.10 127 438 2.6E-68 T 29-03-2018 SMALA_RS24580 b19ee83941c055ec33767990717eb031 451 ProSitePatterns PS00132 Zinc carboxypeptidases, zinc-binding region 1 signature. 183 205 - T 29-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 SMALA_RS29770 2a2d07f02f27bb95638048f5ca621b64 305 SUPERFAMILY SSF161098 51 292 2.62E-50 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS29770 2a2d07f02f27bb95638048f5ca621b64 305 Gene3D G3DSA:1.10.3720.10 8 304 5.4E-47 T 29-03-2018 SMALA_RS29770 2a2d07f02f27bb95638048f5ca621b64 305 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 104 301 6.0E-19 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS39195 0890aabe38d853c0cab36b5574cfdce1 315 PIRSF PIRSF015689 3 290 9.5E-104 T 29-03-2018 IPR003361 Acetaldehyde dehydrogenase GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 SMALA_RS39195 0890aabe38d853c0cab36b5574cfdce1 315 Gene3D G3DSA:3.40.50.720 5 138 1.4E-13 T 29-03-2018 SMALA_RS39195 0890aabe38d853c0cab36b5574cfdce1 315 Gene3D G3DSA:3.30.360.10 139 264 1.0E-35 T 29-03-2018 SMALA_RS39195 0890aabe38d853c0cab36b5574cfdce1 315 Hamap MF_01657 Acetaldehyde dehydrogenase [mhpF]. 1 311 66.862 T 29-03-2018 IPR003361 Acetaldehyde dehydrogenase GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 SMALA_RS39195 0890aabe38d853c0cab36b5574cfdce1 315 Pfam PF09290 Prokaryotic acetaldehyde dehydrogenase, dimerisation 129 264 1.2E-37 T 29-03-2018 IPR015426 Acetaldehyde dehydrogenase, C-terminal GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 SMALA_RS39195 0890aabe38d853c0cab36b5574cfdce1 315 SUPERFAMILY SSF55347 129 264 1.05E-38 T 29-03-2018 SMALA_RS39195 0890aabe38d853c0cab36b5574cfdce1 315 SUPERFAMILY SSF51735 6 141 3.53E-17 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS05215 126661e056d7a4d94da3d6cb69609343 432 SMART SM00458 307 431 2.0E-35 T 29-03-2018 IPR000772 Ricin B, lectin domain SMALA_RS05215 126661e056d7a4d94da3d6cb69609343 432 Pfam PF00652 Ricin-type beta-trefoil lectin domain 308 428 1.5E-31 T 29-03-2018 IPR000772 Ricin B, lectin domain SMALA_RS05215 126661e056d7a4d94da3d6cb69609343 432 Gene3D G3DSA:4.10.1090.10 292 349 1.8E-16 T 29-03-2018 SMALA_RS05215 126661e056d7a4d94da3d6cb69609343 432 Pfam PF00722 Glycosyl hydrolases family 16 90 297 7.7E-43 T 29-03-2018 IPR000757 Glycoside hydrolase family 16 GO:0004553|GO:0005975 SMALA_RS05215 126661e056d7a4d94da3d6cb69609343 432 Gene3D G3DSA:2.80.10.50 389 432 6.6E-15 T 29-03-2018 SMALA_RS05215 126661e056d7a4d94da3d6cb69609343 432 SUPERFAMILY SSF49899 48 299 3.17E-74 T 29-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain SMALA_RS05215 126661e056d7a4d94da3d6cb69609343 432 Gene3D G3DSA:2.80.10.50 350 388 5.7E-15 T 29-03-2018 SMALA_RS05215 126661e056d7a4d94da3d6cb69609343 432 SUPERFAMILY SSF50370 307 430 3.01E-41 T 29-03-2018 IPR000772 Ricin B, lectin domain SMALA_RS05215 126661e056d7a4d94da3d6cb69609343 432 Gene3D G3DSA:2.60.120.200 51 291 5.9E-75 T 29-03-2018 SMALA_RS28415 04dc351e75ddee6504d9fa9223357a49 420 Pfam PF13288 DXP reductoisomerase C-terminal domain 284 402 2.7E-32 T 29-03-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 SMALA_RS28415 04dc351e75ddee6504d9fa9223357a49 420 SUPERFAMILY SSF51735 22 172 9.12E-36 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS28415 04dc351e75ddee6504d9fa9223357a49 420 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 168 251 2.4E-36 T 29-03-2018 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 SMALA_RS28415 04dc351e75ddee6504d9fa9223357a49 420 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 24 407 44.01 T 29-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 SMALA_RS28415 04dc351e75ddee6504d9fa9223357a49 420 PIRSF PIRSF006205 21 414 1.6E-140 T 29-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 SMALA_RS28415 04dc351e75ddee6504d9fa9223357a49 420 Gene3D G3DSA:3.40.50.720 21 172 1.6E-46 T 29-03-2018 SMALA_RS28415 04dc351e75ddee6504d9fa9223357a49 420 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 22 410 1.6E-110 T 29-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 SMALA_RS28415 04dc351e75ddee6504d9fa9223357a49 420 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 24 156 1.9E-38 T 29-03-2018 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 SMALA_RS28415 04dc351e75ddee6504d9fa9223357a49 420 SUPERFAMILY SSF55347 150 286 9.48E-54 T 29-03-2018 SMALA_RS28415 04dc351e75ddee6504d9fa9223357a49 420 SUPERFAMILY SSF69055 314 408 1.96E-25 T 29-03-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 SMALA_RS28415 04dc351e75ddee6504d9fa9223357a49 420 Gene3D G3DSA:1.10.1740.10 325 412 1.2E-29 T 29-03-2018 SMALA_RS32305 fd07035ca089c07dca2d13709c3f8b33 64 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 63 6.6E-24 T 29-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 SMALA_RS32305 fd07035ca089c07dca2d13709c3f8b33 64 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 29-03-2018 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS32305 fd07035ca089c07dca2d13709c3f8b33 64 PRINTS PR00064 Ribosomal protein L35 signature 3 20 7.1E-15 T 29-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 SMALA_RS32305 fd07035ca089c07dca2d13709c3f8b33 64 PRINTS PR00064 Ribosomal protein L35 signature 36 54 7.1E-15 T 29-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 SMALA_RS32305 fd07035ca089c07dca2d13709c3f8b33 64 PRINTS PR00064 Ribosomal protein L35 signature 21 35 7.1E-15 T 29-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 SMALA_RS32305 fd07035ca089c07dca2d13709c3f8b33 64 Pfam PF01632 Ribosomal protein L35 2 62 1.6E-23 T 29-03-2018 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS32305 fd07035ca089c07dca2d13709c3f8b33 64 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 17.238 T 29-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 SMALA_RS32305 fd07035ca089c07dca2d13709c3f8b33 64 SUPERFAMILY SSF143034 2 63 1.57E-20 T 29-03-2018 SMALA_RS00510 eb91b208221b0e646c3347cd666902e4 188 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 24 77 2.0E-9 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SMALA_RS00510 eb91b208221b0e646c3347cd666902e4 188 Pfam PF01799 [2Fe-2S] binding domain 91 179 1.6E-29 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 SMALA_RS00510 eb91b208221b0e646c3347cd666902e4 188 SUPERFAMILY SSF47741 102 184 1.31E-26 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 SMALA_RS00510 eb91b208221b0e646c3347cd666902e4 188 SUPERFAMILY SSF54292 21 105 1.28E-26 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SMALA_RS00510 eb91b208221b0e646c3347cd666902e4 188 Gene3D G3DSA:1.10.150.120 93 186 2.7E-34 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 SMALA_RS00510 eb91b208221b0e646c3347cd666902e4 188 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 57 65 - T 29-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 SMALA_RS00510 eb91b208221b0e646c3347cd666902e4 188 Gene3D G3DSA:3.10.20.30 17 92 1.0E-28 T 29-03-2018 IPR012675 Beta-grasp domain SMALA_RS01325 79df4dff54cb6d318954ddd458a23e9b 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 6.2E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS01325 79df4dff54cb6d318954ddd458a23e9b 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 6.2E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS01325 79df4dff54cb6d318954ddd458a23e9b 192 Gene3D G3DSA:1.10.357.10 1 192 3.7E-43 T 29-03-2018 SMALA_RS01325 79df4dff54cb6d318954ddd458a23e9b 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 65 3.5E-13 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS01325 79df4dff54cb6d318954ddd458a23e9b 192 SUPERFAMILY SSF46689 7 86 8.98E-18 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS01325 79df4dff54cb6d318954ddd458a23e9b 192 SUPERFAMILY SSF48498 86 189 1.45E-11 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS28225 4c8894a60806e552c5e9e9a6bc3a01d5 307 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 3 225 7.7E-107 T 29-03-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS28225 4c8894a60806e552c5e9e9a6bc3a01d5 307 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 2 226 41.992 T 29-03-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS28225 4c8894a60806e552c5e9e9a6bc3a01d5 307 Pfam PF00318 Ribosomal protein S2 9 225 4.2E-95 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS28225 4c8894a60806e552c5e9e9a6bc3a01d5 307 SUPERFAMILY SSF52313 6 233 5.1E-90 T 29-03-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain SMALA_RS28225 4c8894a60806e552c5e9e9a6bc3a01d5 307 Gene3D G3DSA:3.40.50.10490 5 289 3.4E-97 T 29-03-2018 SMALA_RS28225 4c8894a60806e552c5e9e9a6bc3a01d5 307 PRINTS PR00395 Ribosomal protein S2 signature 159 176 4.7E-38 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS28225 4c8894a60806e552c5e9e9a6bc3a01d5 307 PRINTS PR00395 Ribosomal protein S2 signature 87 104 4.7E-38 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS28225 4c8894a60806e552c5e9e9a6bc3a01d5 307 PRINTS PR00395 Ribosomal protein S2 signature 176 187 4.7E-38 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS28225 4c8894a60806e552c5e9e9a6bc3a01d5 307 PRINTS PR00395 Ribosomal protein S2 signature 6 24 4.7E-38 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS28225 4c8894a60806e552c5e9e9a6bc3a01d5 307 PRINTS PR00395 Ribosomal protein S2 signature 197 211 4.7E-38 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS28225 4c8894a60806e552c5e9e9a6bc3a01d5 307 PRINTS PR00395 Ribosomal protein S2 signature 37 46 4.7E-38 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS28225 4c8894a60806e552c5e9e9a6bc3a01d5 307 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 6 17 - T 29-03-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 SMALA_RS09400 fe1dc5053dc9a3f69dad61926c89b89f 303 Gene3D G3DSA:3.40.50.720 1 116 1.8E-20 T 29-03-2018 SMALA_RS09400 fe1dc5053dc9a3f69dad61926c89b89f 303 Gene3D G3DSA:3.90.25.10 161 302 3.3E-24 T 29-03-2018 SMALA_RS09400 fe1dc5053dc9a3f69dad61926c89b89f 303 SUPERFAMILY SSF51735 1 299 2.2E-48 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS09400 fe1dc5053dc9a3f69dad61926c89b89f 303 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 218 9.9E-19 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 SMALA_RS11245 b6cdbfb1077a2e141ec8822192a9b48f 153 PRINTS PR00421 Thioredoxin family signature 69 78 5.5E-6 T 29-03-2018 SMALA_RS11245 b6cdbfb1077a2e141ec8822192a9b48f 153 PRINTS PR00421 Thioredoxin family signature 61 69 5.5E-6 T 29-03-2018 SMALA_RS11245 b6cdbfb1077a2e141ec8822192a9b48f 153 PRINTS PR00421 Thioredoxin family signature 109 120 5.5E-6 T 29-03-2018 SMALA_RS11245 b6cdbfb1077a2e141ec8822192a9b48f 153 Gene3D G3DSA:3.40.30.10 40 152 5.5E-32 T 29-03-2018 SMALA_RS11245 b6cdbfb1077a2e141ec8822192a9b48f 153 TIGRFAM TIGR01068 thioredoxin: thioredoxin 48 144 1.1E-31 T 29-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 SMALA_RS11245 b6cdbfb1077a2e141ec8822192a9b48f 153 Pfam PF00085 Thioredoxin 47 143 1.1E-25 T 29-03-2018 IPR013766 Thioredoxin domain GO:0045454 SMALA_RS11245 b6cdbfb1077a2e141ec8822192a9b48f 153 SUPERFAMILY SSF52833 45 145 4.63E-32 T 29-03-2018 IPR012336 Thioredoxin-like fold SMALA_RS11245 b6cdbfb1077a2e141ec8822192a9b48f 153 ProSitePatterns PS00194 Thioredoxin family active site. 62 80 - T 29-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 SMALA_RS42320 19bd71344737324099132fe52ec22fbc 700 SUPERFAMILY SSF63380 366 465 3.74E-24 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 SMALA_RS42320 19bd71344737324099132fe52ec22fbc 700 Gene3D G3DSA:2.40.30.10 357 454 4.5E-19 T 29-03-2018 SMALA_RS42320 19bd71344737324099132fe52ec22fbc 700 Gene3D G3DSA:2.30.110.10 52 132 0.3 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS42320 19bd71344737324099132fe52ec22fbc 700 Pfam PF00175 Oxidoreductase NAD-binding domain 476 578 1.3E-14 T 29-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 SMALA_RS42320 19bd71344737324099132fe52ec22fbc 700 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 416 423 2.2E-6 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 SMALA_RS42320 19bd71344737324099132fe52ec22fbc 700 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 501 510 2.2E-6 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 SMALA_RS42320 19bd71344737324099132fe52ec22fbc 700 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 475 494 2.2E-6 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 SMALA_RS42320 19bd71344737324099132fe52ec22fbc 700 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 513 524 2.2E-6 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 SMALA_RS42320 19bd71344737324099132fe52ec22fbc 700 SUPERFAMILY SSF52343 455 594 1.06E-33 T 29-03-2018 SMALA_RS42320 19bd71344737324099132fe52ec22fbc 700 SUPERFAMILY SSF54292 587 698 9.31E-25 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SMALA_RS42320 19bd71344737324099132fe52ec22fbc 700 Gene3D G3DSA:3.40.50.80 455 589 5.3E-30 T 29-03-2018 SMALA_RS42320 19bd71344737324099132fe52ec22fbc 700 PRINTS PR00410 Phenol hydroxylase reductase family signature 459 468 1.6E-8 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 SMALA_RS42320 19bd71344737324099132fe52ec22fbc 700 PRINTS PR00410 Phenol hydroxylase reductase family signature 397 409 1.6E-8 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 SMALA_RS42320 19bd71344737324099132fe52ec22fbc 700 PRINTS PR00410 Phenol hydroxylase reductase family signature 564 572 1.6E-8 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 SMALA_RS42320 19bd71344737324099132fe52ec22fbc 700 PRINTS PR00410 Phenol hydroxylase reductase family signature 475 494 1.6E-8 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 SMALA_RS42320 19bd71344737324099132fe52ec22fbc 700 Gene3D G3DSA:3.10.20.30 590 699 2.4E-22 T 29-03-2018 IPR012675 Beta-grasp domain SMALA_RS42320 19bd71344737324099132fe52ec22fbc 700 SUPERFAMILY SSF50475 139 255 3.65E-12 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS42320 19bd71344737324099132fe52ec22fbc 700 Gene3D G3DSA:2.30.110.10 137 282 2.5E-15 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS42320 19bd71344737324099132fe52ec22fbc 700 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 616 686 1.2E-11 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SMALA_RS42320 19bd71344737324099132fe52ec22fbc 700 Pfam PF00970 Oxidoreductase FAD-binding domain 395 465 1.3E-11 T 29-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 SMALA_RS42320 19bd71344737324099132fe52ec22fbc 700 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 140 229 1.5E-6 T 29-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 SMALA_RS31355 a678712e2daf14f8ed7f341b8406b059 351 Gene3D G3DSA:3.40.50.2300 57 177 4.1E-21 T 29-03-2018 SMALA_RS31355 a678712e2daf14f8ed7f341b8406b059 351 SUPERFAMILY SSF53822 56 346 1.03E-65 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SMALA_RS31355 a678712e2daf14f8ed7f341b8406b059 351 Pfam PF13407 Periplasmic binding protein domain 59 316 7.0E-47 T 29-03-2018 IPR025997 Periplasmic binding protein SMALA_RS31355 a678712e2daf14f8ed7f341b8406b059 351 Gene3D G3DSA:3.40.50.2300 178 347 1.1E-24 T 29-03-2018 SMALA_RS25625 2fef653f183e14b282d1a6d2198d485c 373 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS25625 2fef653f183e14b282d1a6d2198d485c 373 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 292 337 4.5E-11 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMALA_RS25625 2fef653f183e14b282d1a6d2198d485c 373 SUPERFAMILY SSF52540 4 254 1.33E-65 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS25625 2fef653f183e14b282d1a6d2198d485c 373 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 293 326 2.3E-6 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMALA_RS25625 2fef653f183e14b282d1a6d2198d485c 373 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 267 1.1E-8 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMALA_RS25625 2fef653f183e14b282d1a6d2198d485c 373 SMART SM00382 33 233 3.4E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS25625 2fef653f183e14b282d1a6d2198d485c 373 Pfam PF00005 ABC transporter 26 183 3.4E-24 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS25625 2fef653f183e14b282d1a6d2198d485c 373 Gene3D G3DSA:3.40.50.300 1 354 1.6E-68 T 29-03-2018 SMALA_RS33650 4f80920e8236994e6ccaecf725b6d484 272 Pfam PF08282 haloacid dehalogenase-like hydrolase 17 65 1.4E-5 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS33650 4f80920e8236994e6ccaecf725b6d484 272 Pfam PF08282 haloacid dehalogenase-like hydrolase 182 243 2.9E-5 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS33650 4f80920e8236994e6ccaecf725b6d484 272 SUPERFAMILY SSF56784 14 234 8.81E-20 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS33650 4f80920e8236994e6ccaecf725b6d484 272 Gene3D G3DSA:3.40.50.1000 2 258 3.8E-17 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS15395 c3c44a8ce76f58635176ae0e1d0b368d 198 Pfam PF07336 Putative stress-induced transcription regulator 14 145 7.6E-23 T 29-03-2018 IPR010852 Putative stress-induced transcription regulator SMALA_RS15395 c3c44a8ce76f58635176ae0e1d0b368d 198 Gene3D G3DSA:1.10.3300.10 4 195 8.5E-55 T 29-03-2018 IPR023286 ABATE domain SMALA_RS15395 c3c44a8ce76f58635176ae0e1d0b368d 198 Pfam PF11706 CGNR zinc finger 151 192 4.7E-17 T 29-03-2018 IPR021005 Zinc finger, CGNR SMALA_RS15395 c3c44a8ce76f58635176ae0e1d0b368d 198 SUPERFAMILY SSF160904 9 192 7.85E-43 T 29-03-2018 SMALA_RS19695 2353386c4019b8d650c86dbdfad5bba7 379 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 35 252 7.4E-62 T 29-03-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal SMALA_RS19695 2353386c4019b8d650c86dbdfad5bba7 379 Pfam PF02096 60Kd inner membrane protein 35 252 1.3E-58 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 SMALA_RS07265 14f720a15d74204cfd1ccd9b4cce4b57 588 Gene3D G3DSA:1.20.5.340 19 172 1.2E-6 T 29-03-2018 SMALA_RS07265 14f720a15d74204cfd1ccd9b4cce4b57 588 SUPERFAMILY SSF52540 475 515 2.7E-51 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS07265 14f720a15d74204cfd1ccd9b4cce4b57 588 SUPERFAMILY SSF52540 227 434 2.7E-51 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS07265 14f720a15d74204cfd1ccd9b4cce4b57 588 TIGRFAM TIGR03689 pup_AAA: proteasome ATPase 52 565 1.3E-252 T 29-03-2018 IPR022482 Proteasome ATPase GO:0000502|GO:0010498|GO:0016887|GO:0019941 SMALA_RS07265 14f720a15d74204cfd1ccd9b4cce4b57 588 SMART SM00382 265 419 6.5E-22 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS07265 14f720a15d74204cfd1ccd9b4cce4b57 588 Hamap MF_02112 Proteasome-associated ATPase [mpa]. 54 566 50.333 T 29-03-2018 IPR022482 Proteasome ATPase GO:0000502|GO:0010498|GO:0016887|GO:0019941 SMALA_RS07265 14f720a15d74204cfd1ccd9b4cce4b57 588 ProSitePatterns PS00674 AAA-protein family signature. 387 405 - T 29-03-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 SMALA_RS07265 14f720a15d74204cfd1ccd9b4cce4b57 588 Pfam PF16450 Proteasomal ATPase OB/ID domain 97 226 5.6E-53 T 29-03-2018 IPR032501 Proteasomal ATPase, OB/ID domain SMALA_RS07265 14f720a15d74204cfd1ccd9b4cce4b57 588 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 269 417 1.8E-48 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 SMALA_RS07265 14f720a15d74204cfd1ccd9b4cce4b57 588 Gene3D G3DSA:3.40.50.300 211 434 5.0E-53 T 29-03-2018 SMALA_RS21780 641287091d3f5162a6fa0350b80bda8c 69 Gene3D G3DSA:1.10.10.10 28 67 6.8E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS21780 641287091d3f5162a6fa0350b80bda8c 69 Pfam PF12728 Helix-turn-helix domain 13 61 4.4E-14 T 29-03-2018 SMALA_RS21780 641287091d3f5162a6fa0350b80bda8c 69 SUPERFAMILY SSF46955 13 62 1.59E-5 T 29-03-2018 IPR009061 Putative DNA-binding domain SMALA_RS21780 641287091d3f5162a6fa0350b80bda8c 69 Gene3D G3DSA:1.10.10.60 3 27 0.0013 T 29-03-2018 SMALA_RS21780 641287091d3f5162a6fa0350b80bda8c 69 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 13 60 3.6E-21 T 29-03-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 SMALA_RS21810 99f3edc1dc57d2faa90c39a4145d5a67 307 SUPERFAMILY SSF56784 55 268 3.47E-29 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS21810 99f3edc1dc57d2faa90c39a4145d5a67 307 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 56 245 1.9E-15 T 29-03-2018 SMALA_RS21810 99f3edc1dc57d2faa90c39a4145d5a67 307 Pfam PF12710 haloacid dehalogenase-like hydrolase 57 243 1.5E-27 T 29-03-2018 SMALA_RS21810 99f3edc1dc57d2faa90c39a4145d5a67 307 Gene3D G3DSA:3.40.50.1000 130 281 3.1E-22 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS21810 99f3edc1dc57d2faa90c39a4145d5a67 307 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 56 257 5.7E-53 T 29-03-2018 IPR006385 HAD-superfamily hydrolase, subfamily IB, SerB1-like SMALA_RS25665 2b11647e547c0c2a72aee6cc4382326c 355 ProSitePatterns PS00211 ABC transporters family signature. 172 186 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS25665 2b11647e547c0c2a72aee6cc4382326c 355 Gene3D G3DSA:3.40.50.300 19 351 5.6E-74 T 29-03-2018 SMALA_RS25665 2b11647e547c0c2a72aee6cc4382326c 355 SUPERFAMILY SSF52540 22 270 8.68E-69 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS25665 2b11647e547c0c2a72aee6cc4382326c 355 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 251 312 5.7E-17 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMALA_RS25665 2b11647e547c0c2a72aee6cc4382326c 355 SMART SM00382 50 249 3.8E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS25665 2b11647e547c0c2a72aee6cc4382326c 355 Pfam PF00005 ABC transporter 42 199 4.4E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS25665 2b11647e547c0c2a72aee6cc4382326c 355 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 250 336 2.1E-20 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMALA_RS34855 5990f1face5d26a4a5b75b9e4bbdacfa 500 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 363 372 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMALA_RS34855 5990f1face5d26a4a5b75b9e4bbdacfa 500 Gene3D G3DSA:1.10.630.10 25 425 1.0E-41 T 29-03-2018 SMALA_RS34855 5990f1face5d26a4a5b75b9e4bbdacfa 500 SUPERFAMILY SSF48264 20 424 1.44E-66 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS34855 5990f1face5d26a4a5b75b9e4bbdacfa 500 PRINTS PR00359 B-class P450 signature 184 199 5.8E-25 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS34855 5990f1face5d26a4a5b75b9e4bbdacfa 500 PRINTS PR00359 B-class P450 signature 167 183 5.8E-25 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS34855 5990f1face5d26a4a5b75b9e4bbdacfa 500 PRINTS PR00359 B-class P450 signature 314 341 5.8E-25 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS34855 5990f1face5d26a4a5b75b9e4bbdacfa 500 PRINTS PR00359 B-class P450 signature 218 240 5.8E-25 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS34855 5990f1face5d26a4a5b75b9e4bbdacfa 500 PRINTS PR00359 B-class P450 signature 121 132 5.8E-25 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS34855 5990f1face5d26a4a5b75b9e4bbdacfa 500 PRINTS PR00359 B-class P450 signature 361 370 5.8E-25 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS08155 849645a0cbd9b054b45d713cda9df006 944 Gene3D G3DSA:1.10.439.10 121 302 1.3E-37 T 29-03-2018 IPR023343 Penicillin amidase type, domain1 GO:0016811 SMALA_RS08155 849645a0cbd9b054b45d713cda9df006 944 Pfam PF01804 Penicillin amidase 133 931 1.1E-122 T 29-03-2018 IPR002692 Penicillin/GL-7-ACA/AHL/aculeacin-A acylase GO:0016787|GO:0017000 SMALA_RS08155 849645a0cbd9b054b45d713cda9df006 944 Gene3D G3DSA:1.10.287.150 303 344 5.9E-19 T 29-03-2018 SMALA_RS08155 849645a0cbd9b054b45d713cda9df006 944 Gene3D G3DSA:3.60.20.10 412 943 1.3E-68 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SMALA_RS08155 849645a0cbd9b054b45d713cda9df006 944 SUPERFAMILY SSF56235 132 337 3.34E-100 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SMALA_RS08155 849645a0cbd9b054b45d713cda9df006 944 SUPERFAMILY SSF56235 404 816 3.34E-100 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SMALA_RS23005 ad31f209030694620f32a4052306e1f2 936 Gene3D G3DSA:3.30.200.20 29 144 3.3E-5 T 29-03-2018 SMALA_RS23005 ad31f209030694620f32a4052306e1f2 936 Gene3D G3DSA:3.40.1000.10 796 934 6.5E-6 T 29-03-2018 SMALA_RS23005 ad31f209030694620f32a4052306e1f2 936 SMART SM00220 23 611 2.1E-8 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMALA_RS23005 ad31f209030694620f32a4052306e1f2 936 Pfam PF00069 Protein kinase domain 104 187 2.9E-7 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMALA_RS23005 ad31f209030694620f32a4052306e1f2 936 SUPERFAMILY SSF56112 518 610 1.53E-19 T 29-03-2018 IPR011009 Protein kinase-like domain SMALA_RS23005 ad31f209030694620f32a4052306e1f2 936 SUPERFAMILY SSF56112 99 190 1.53E-19 T 29-03-2018 IPR011009 Protein kinase-like domain SMALA_RS23005 ad31f209030694620f32a4052306e1f2 936 Gene3D G3DSA:1.10.510.10 145 695 3.1E-41 T 29-03-2018 SMALA_RS33380 d2440723c8efd9111f93876279b18842 324 SUPERFAMILY SSF63829 36 274 4.12E-7 T 29-03-2018 SMALA_RS33380 d2440723c8efd9111f93876279b18842 324 Gene3D G3DSA:2.120.10.30 8 315 7.1E-7 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like SMALA_RS19640 29591e1647cfeb22123541d0bbe9f5c4 753 Pfam PF03023 MviN-like protein 243 717 2.0E-122 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ SMALA_RS19640 29591e1647cfeb22123541d0bbe9f5c4 753 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 213 743 1.8E-137 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ SMALA_RS19640 29591e1647cfeb22123541d0bbe9f5c4 753 PRINTS PR01806 Virulence factor MviN signature 367 388 7.5E-16 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ SMALA_RS19640 29591e1647cfeb22123541d0bbe9f5c4 753 PRINTS PR01806 Virulence factor MviN signature 244 263 7.5E-16 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ SMALA_RS19640 29591e1647cfeb22123541d0bbe9f5c4 753 PRINTS PR01806 Virulence factor MviN signature 644 661 7.5E-16 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ SMALA_RS19640 29591e1647cfeb22123541d0bbe9f5c4 753 PRINTS PR01806 Virulence factor MviN signature 588 607 7.5E-16 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ SMALA_RS19640 29591e1647cfeb22123541d0bbe9f5c4 753 PRINTS PR01806 Virulence factor MviN signature 263 279 7.5E-16 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ SMALA_RS19640 29591e1647cfeb22123541d0bbe9f5c4 753 PRINTS PR01806 Virulence factor MviN signature 343 367 7.5E-16 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ SMALA_RS30980 a6542b5a14462fdc5cfcd748e17015ed 269 Gene3D G3DSA:3.40.50.150 3 258 4.3E-42 T 29-03-2018 SMALA_RS30980 a6542b5a14462fdc5cfcd748e17015ed 269 Pfam PF13847 Methyltransferase domain 38 152 6.5E-29 T 29-03-2018 IPR025714 Methyltransferase domain SMALA_RS30980 a6542b5a14462fdc5cfcd748e17015ed 269 SUPERFAMILY SSF53335 6 250 2.01E-45 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS12905 ec03e6012be5e012b4d17394fad5df1c 434 Gene3D G3DSA:3.30.465.10 340 430 2.1E-20 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SMALA_RS12905 ec03e6012be5e012b4d17394fad5df1c 434 Pfam PF01595 Domain of unknown function DUF21 9 185 3.0E-30 T 29-03-2018 IPR002550 Domain of unknown function DUF21 SMALA_RS12905 ec03e6012be5e012b4d17394fad5df1c 434 Pfam PF00571 CBS domain 200 256 8.0E-8 T 29-03-2018 IPR000644 CBS domain SMALA_RS12905 ec03e6012be5e012b4d17394fad5df1c 434 Pfam PF00571 CBS domain 275 322 1.4E-6 T 29-03-2018 IPR000644 CBS domain SMALA_RS12905 ec03e6012be5e012b4d17394fad5df1c 434 SMART SM00116 209 258 0.0012 T 29-03-2018 IPR000644 CBS domain SMALA_RS12905 ec03e6012be5e012b4d17394fad5df1c 434 SMART SM00116 274 322 1.6 T 29-03-2018 IPR000644 CBS domain SMALA_RS12905 ec03e6012be5e012b4d17394fad5df1c 434 SMART SM01091 337 428 3.5E-14 T 29-03-2018 IPR005170 Transporter-associated domain SMALA_RS12905 ec03e6012be5e012b4d17394fad5df1c 434 SUPERFAMILY SSF56176 336 430 1.39E-12 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SMALA_RS12905 ec03e6012be5e012b4d17394fad5df1c 434 Pfam PF03471 Transporter associated domain 339 427 6.2E-13 T 29-03-2018 IPR005170 Transporter-associated domain SMALA_RS12905 ec03e6012be5e012b4d17394fad5df1c 434 Gene3D G3DSA:3.20.20.70 149 339 2.9E-34 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS12905 ec03e6012be5e012b4d17394fad5df1c 434 SUPERFAMILY SSF54631 195 340 1.39E-34 T 29-03-2018 SMALA_RS23125 b8e0e6df69272249b4705c4dd67966a6 264 SUPERFAMILY SSF54593 137 258 1.21E-11 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS23125 b8e0e6df69272249b4705c4dd67966a6 264 SUPERFAMILY SSF54593 17 124 1.05E-15 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS23125 b8e0e6df69272249b4705c4dd67966a6 264 Gene3D G3DSA:3.10.180.10 137 263 4.8E-13 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS23125 b8e0e6df69272249b4705c4dd67966a6 264 Gene3D G3DSA:3.10.180.10 9 129 8.9E-16 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS15690 4d44b60071ec10128b4dbed7411c12e4 270 Pfam PF13489 Methyltransferase domain 41 211 2.9E-15 T 29-03-2018 SMALA_RS15690 4d44b60071ec10128b4dbed7411c12e4 270 SUPERFAMILY SSF53335 11 226 1.07E-30 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS15690 4d44b60071ec10128b4dbed7411c12e4 270 Gene3D G3DSA:3.40.50.150 12 270 1.1E-29 T 29-03-2018 SMALA_RS28180 1cc53dc7e561ee59c95b65bf4ccc9242 177 ProSitePatterns PS00893 Nudix box signature. 55 76 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 SMALA_RS28180 1cc53dc7e561ee59c95b65bf4ccc9242 177 PRINTS PR00502 NUDIX hydrolase family signature 64 79 9.0E-6 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMALA_RS28180 1cc53dc7e561ee59c95b65bf4ccc9242 177 PRINTS PR00502 NUDIX hydrolase family signature 50 64 9.0E-6 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMALA_RS28180 1cc53dc7e561ee59c95b65bf4ccc9242 177 Pfam PF00293 NUDIX domain 19 144 3.5E-20 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SMALA_RS28180 1cc53dc7e561ee59c95b65bf4ccc9242 177 Gene3D G3DSA:3.90.79.10 3 164 4.2E-24 T 29-03-2018 SMALA_RS28180 1cc53dc7e561ee59c95b65bf4ccc9242 177 SUPERFAMILY SSF55811 17 152 7.45E-22 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMALA_RS41545 7f907737a808d53f6a89db330d4e340f 221 Gene3D G3DSA:1.10.357.10 10 220 2.8E-23 T 29-03-2018 SMALA_RS41545 7f907737a808d53f6a89db330d4e340f 221 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 65 2.1E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS41545 7f907737a808d53f6a89db330d4e340f 221 SUPERFAMILY SSF46689 8 79 1.85E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS07195 79e4abf4b25cba76aba7285c882abeb1 95 Pfam PF02416 mttA/Hcf106 family 5 55 4.8E-18 T 29-03-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 SMALA_RS07195 79e4abf4b25cba76aba7285c882abeb1 95 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 5 49 9.8E-18 T 29-03-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 SMALA_RS07195 79e4abf4b25cba76aba7285c882abeb1 95 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 2 76 20.017 T 29-03-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 SMALA_RS27705 41a85fbfc9adaa2b4214469d5b14c2b7 312 Gene3D G3DSA:3.40.50.720 111 280 3.8E-47 T 29-03-2018 SMALA_RS27705 41a85fbfc9adaa2b4214469d5b14c2b7 312 SUPERFAMILY SSF52283 46 129 5.74E-9 T 29-03-2018 SMALA_RS27705 41a85fbfc9adaa2b4214469d5b14c2b7 312 Gene3D G3DSA:3.40.50.720 22 110 4.3E-16 T 29-03-2018 SMALA_RS27705 41a85fbfc9adaa2b4214469d5b14c2b7 312 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 217 233 - T 29-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site SMALA_RS27705 41a85fbfc9adaa2b4214469d5b14c2b7 312 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 57 308 1.2E-6 T 29-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 SMALA_RS27705 41a85fbfc9adaa2b4214469d5b14c2b7 312 SUPERFAMILY SSF51735 98 278 4.78E-45 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS27705 41a85fbfc9adaa2b4214469d5b14c2b7 312 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 105 277 2.7E-45 T 29-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 SMALA_RS39760 cd2b132c808774f9acc4c3f22beddaee 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 247 2.0E-63 T 29-03-2018 SMALA_RS39760 cd2b132c808774f9acc4c3f22beddaee 256 Gene3D G3DSA:3.40.50.720 48 253 1.7E-56 T 29-03-2018 SMALA_RS39760 cd2b132c808774f9acc4c3f22beddaee 256 Gene3D G3DSA:3.40.50.720 1 47 3.8E-13 T 29-03-2018 SMALA_RS39760 cd2b132c808774f9acc4c3f22beddaee 256 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMALA_RS39760 cd2b132c808774f9acc4c3f22beddaee 256 SUPERFAMILY SSF51735 6 248 1.45E-78 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS39760 cd2b132c808774f9acc4c3f22beddaee 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 4.4E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS39760 cd2b132c808774f9acc4c3f22beddaee 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 4.4E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS39760 cd2b132c808774f9acc4c3f22beddaee 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 4.4E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS39760 cd2b132c808774f9acc4c3f22beddaee 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 2.4E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS39760 cd2b132c808774f9acc4c3f22beddaee 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 2.4E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS39760 cd2b132c808774f9acc4c3f22beddaee 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 2.4E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS39760 cd2b132c808774f9acc4c3f22beddaee 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 2.4E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS39760 cd2b132c808774f9acc4c3f22beddaee 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 2.4E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS39760 cd2b132c808774f9acc4c3f22beddaee 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 2.4E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS09990 9e74186dd437765779007cce390caa9f 125 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 40 112 3.2E-33 T 29-03-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 SMALA_RS09990 9e74186dd437765779007cce390caa9f 125 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 14 117 31.104 T 29-03-2018 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 SMALA_RS09990 9e74186dd437765779007cce390caa9f 125 SUPERFAMILY SSF141734 14 114 4.84E-46 T 29-03-2018 SMALA_RS09990 9e74186dd437765779007cce390caa9f 125 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 63 117 1.0E-21 T 29-03-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 SMALA_RS18140 ce292a5a98de6ca9096529b8150eb5df 163 SUPERFAMILY SSF50324 3 156 1.44E-57 T 29-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 SMALA_RS18140 ce292a5a98de6ca9096529b8150eb5df 163 Pfam PF00719 Inorganic pyrophosphatase 5 157 3.5E-53 T 29-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 SMALA_RS18140 ce292a5a98de6ca9096529b8150eb5df 163 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 1 158 32.825 T 29-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 SMALA_RS18140 ce292a5a98de6ca9096529b8150eb5df 163 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 52 58 - T 29-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 SMALA_RS18140 ce292a5a98de6ca9096529b8150eb5df 163 Gene3D G3DSA:3.90.80.10 1 161 2.3E-53 T 29-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 SMALA_RS00925 7d88c6410a63409ab122e91a30f6a27f 355 ProSitePatterns PS00211 ABC transporters family signature. 173 187 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS00925 7d88c6410a63409ab122e91a30f6a27f 355 SUPERFAMILY SSF52540 27 272 9.74E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS00925 7d88c6410a63409ab122e91a30f6a27f 355 SMART SM00382 51 249 1.8E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS00925 7d88c6410a63409ab122e91a30f6a27f 355 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 252 316 1.0E-17 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMALA_RS00925 7d88c6410a63409ab122e91a30f6a27f 355 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 251 335 9.9E-20 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMALA_RS00925 7d88c6410a63409ab122e91a30f6a27f 355 Gene3D G3DSA:3.40.50.300 22 348 8.1E-70 T 29-03-2018 SMALA_RS00925 7d88c6410a63409ab122e91a30f6a27f 355 Pfam PF00005 ABC transporter 43 200 3.6E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS25155 53c8595920b9e4f25b820d0e4e9dd2f5 270 SUPERFAMILY SSF47413 31 81 5.32E-8 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS25155 53c8595920b9e4f25b820d0e4e9dd2f5 270 Gene3D G3DSA:1.10.260.40 2 89 2.3E-14 T 29-03-2018 SMALA_RS25155 53c8595920b9e4f25b820d0e4e9dd2f5 270 Pfam PF13560 Helix-turn-helix domain 9 87 1.5E-14 T 29-03-2018 SMALA_RS25155 53c8595920b9e4f25b820d0e4e9dd2f5 270 SMART SM00530 12 84 1.1E-6 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS06000 650c1e7cd1a7425d4a1b76d0ddf90acc 222 Pfam PF09335 SNARE associated Golgi protein 46 176 7.7E-17 T 29-03-2018 IPR032816 SNARE associated Golgi protein SMALA_RS32085 31962afcf9df652636d4a973122d2e93 246 Gene3D G3DSA:1.10.357.10 68 238 8.9E-22 T 29-03-2018 SMALA_RS32085 31962afcf9df652636d4a973122d2e93 246 SUPERFAMILY SSF46689 13 87 4.99E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS32085 31962afcf9df652636d4a973122d2e93 246 Gene3D G3DSA:1.10.10.60 11 67 9.2E-17 T 29-03-2018 SMALA_RS32085 31962afcf9df652636d4a973122d2e93 246 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 7.5E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS32085 31962afcf9df652636d4a973122d2e93 246 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 7.5E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS32085 31962afcf9df652636d4a973122d2e93 246 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 70 2.8E-13 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS32085 31962afcf9df652636d4a973122d2e93 246 SUPERFAMILY SSF48498 98 234 1.16E-21 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS19150 5be609f70b3fe35ff6b13d2da913383b 143 SUPERFAMILY SSF54197 2 140 2.17E-28 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 SMALA_RS19150 5be609f70b3fe35ff6b13d2da913383b 143 Gene3D G3DSA:3.30.428.10 1 143 4.0E-27 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 SMALA_RS19150 5be609f70b3fe35ff6b13d2da913383b 143 Pfam PF01230 HIT domain 13 109 1.9E-16 T 29-03-2018 IPR001310 Histidine triad (HIT) protein SMALA_RS03340 4c0c9d2a7c4047096906fc87a016fc64 250 Gene3D G3DSA:1.10.1660.10 11 122 2.8E-21 T 29-03-2018 SMALA_RS03340 4c0c9d2a7c4047096906fc87a016fc64 250 SUPERFAMILY SSF46955 36 99 8.24E-13 T 29-03-2018 IPR009061 Putative DNA-binding domain SMALA_RS03340 4c0c9d2a7c4047096906fc87a016fc64 250 Gene3D G3DSA:1.10.1660.10 127 243 0.005 T 29-03-2018 SMALA_RS03340 4c0c9d2a7c4047096906fc87a016fc64 250 Pfam PF00376 MerR family regulatory protein 22 63 3.3E-11 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS03340 4c0c9d2a7c4047096906fc87a016fc64 250 SMART SM00422 21 95 2.8E-17 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS17105 3f2f7b395cc50970c2b9d5ec2cdcaa5e 289 Gene3D G3DSA:3.30.70.260 6 94 9.4E-31 T 29-03-2018 SMALA_RS17105 3f2f7b395cc50970c2b9d5ec2cdcaa5e 289 TIGRFAM TIGR00655 PurU: formyltetrahydrofolate deformylase 12 288 1.0E-101 T 29-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 SMALA_RS17105 3f2f7b395cc50970c2b9d5ec2cdcaa5e 289 Hamap MF_01927 Formyltetrahydrofolate deformylase [purU]. 8 288 47.941 T 29-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 SMALA_RS17105 3f2f7b395cc50970c2b9d5ec2cdcaa5e 289 PIRSF PIRSF036480 8 289 3.2E-113 T 29-03-2018 SMALA_RS17105 3f2f7b395cc50970c2b9d5ec2cdcaa5e 289 Pfam PF00551 Formyl transferase 93 270 1.0E-36 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SMALA_RS17105 3f2f7b395cc50970c2b9d5ec2cdcaa5e 289 SUPERFAMILY SSF53328 93 289 2.09E-62 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SMALA_RS17105 3f2f7b395cc50970c2b9d5ec2cdcaa5e 289 Gene3D G3DSA:3.40.50.170 95 285 1.5E-55 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SMALA_RS17105 3f2f7b395cc50970c2b9d5ec2cdcaa5e 289 SUPERFAMILY SSF55021 10 90 1.75E-18 T 29-03-2018 SMALA_RS17105 3f2f7b395cc50970c2b9d5ec2cdcaa5e 289 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 116 143 1.5E-51 T 29-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 SMALA_RS17105 3f2f7b395cc50970c2b9d5ec2cdcaa5e 289 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 240 262 1.5E-51 T 29-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 SMALA_RS17105 3f2f7b395cc50970c2b9d5ec2cdcaa5e 289 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 13 39 1.5E-51 T 29-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 SMALA_RS17105 3f2f7b395cc50970c2b9d5ec2cdcaa5e 289 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 94 116 1.5E-51 T 29-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 SMALA_RS17105 3f2f7b395cc50970c2b9d5ec2cdcaa5e 289 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 45 57 1.5E-51 T 29-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 SMALA_RS17105 3f2f7b395cc50970c2b9d5ec2cdcaa5e 289 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 262 287 1.5E-51 T 29-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 SMALA_RS09830 ffeadc8ebd39b8d636389f9fee8450bb 212 Pfam PF00072 Response regulator receiver domain 20 129 1.2E-28 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS09830 ffeadc8ebd39b8d636389f9fee8450bb 212 Pfam PF03861 ANTAR domain 148 200 7.8E-21 T 29-03-2018 IPR005561 ANTAR domain GO:0003723 SMALA_RS09830 ffeadc8ebd39b8d636389f9fee8450bb 212 PIRSF PIRSF036382 10 207 4.8E-69 T 29-03-2018 IPR008327 Signal transduction response regulator, antiterminator SMALA_RS09830 ffeadc8ebd39b8d636389f9fee8450bb 212 SMART SM00448 18 129 1.2E-37 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS09830 ffeadc8ebd39b8d636389f9fee8450bb 212 Gene3D G3DSA:1.10.10.10 160 202 1.5E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS09830 ffeadc8ebd39b8d636389f9fee8450bb 212 SMART SM01012 145 200 1.7E-24 T 29-03-2018 IPR005561 ANTAR domain GO:0003723 SMALA_RS09830 ffeadc8ebd39b8d636389f9fee8450bb 212 SUPERFAMILY SSF52172 17 200 4.27E-55 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS09830 ffeadc8ebd39b8d636389f9fee8450bb 212 Gene3D G3DSA:3.40.50.2300 15 159 6.1E-36 T 29-03-2018 SMALA_RS04755 9ee5803ab00e33954c5e3bc4a5a647bf 160 Gene3D G3DSA:3.90.420.10 12 156 6.4E-22 T 29-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 SMALA_RS04755 9ee5803ab00e33954c5e3bc4a5a647bf 160 SUPERFAMILY SSF56524 18 152 1.23E-15 T 29-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 SMALA_RS04755 9ee5803ab00e33954c5e3bc4a5a647bf 160 Pfam PF00174 Oxidoreductase molybdopterin binding domain 18 127 9.7E-7 T 29-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 SMALA_RS25340 ab1a2f5c1dadfb9a35a047a6bf4ac65c 257 SMART SM00422 3 72 2.7E-14 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS25340 ab1a2f5c1dadfb9a35a047a6bf4ac65c 257 Gene3D G3DSA:1.10.1660.10 57 131 1.0E-7 T 29-03-2018 SMALA_RS25340 ab1a2f5c1dadfb9a35a047a6bf4ac65c 257 Gene3D G3DSA:1.10.1660.10 1 56 1.2E-16 T 29-03-2018 SMALA_RS25340 ab1a2f5c1dadfb9a35a047a6bf4ac65c 257 Pfam PF13411 MerR HTH family regulatory protein 4 67 5.2E-11 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS25340 ab1a2f5c1dadfb9a35a047a6bf4ac65c 257 SUPERFAMILY SSF46955 4 103 1.1E-20 T 29-03-2018 IPR009061 Putative DNA-binding domain SMALA_RS31035 9833a61ccd54bad1157b80f4f1ad3263 262 SMART SM01012 172 227 1.3E-20 T 29-03-2018 IPR005561 ANTAR domain GO:0003723 SMALA_RS31035 9833a61ccd54bad1157b80f4f1ad3263 262 PIRSF PIRSF036625 1 236 3.8E-32 T 29-03-2018 IPR012074 GAF-ANTAR transcription anti-termination regulator, putative SMALA_RS31035 9833a61ccd54bad1157b80f4f1ad3263 262 SUPERFAMILY SSF55781 35 168 2.35E-9 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS31035 9833a61ccd54bad1157b80f4f1ad3263 262 Pfam PF03861 ANTAR domain 174 227 5.4E-20 T 29-03-2018 IPR005561 ANTAR domain GO:0003723 SMALA_RS31035 9833a61ccd54bad1157b80f4f1ad3263 262 Gene3D G3DSA:1.10.10.10 181 229 1.2E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS31035 9833a61ccd54bad1157b80f4f1ad3263 262 Gene3D G3DSA:3.30.450.40 7 180 3.3E-12 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS34670 8b1c7b33774f0f4785d9cbe1b05d011c 477 Pfam PF00206 Lyase 54 301 1.2E-20 T 29-03-2018 IPR022761 Fumarate lyase, N-terminal SMALA_RS34670 8b1c7b33774f0f4785d9cbe1b05d011c 477 Gene3D G3DSA:1.10.40.30 383 454 1.1E-14 T 29-03-2018 SMALA_RS34670 8b1c7b33774f0f4785d9cbe1b05d011c 477 ProSitePatterns PS00163 Fumarate lyases signature. 280 289 - T 29-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 SMALA_RS34670 8b1c7b33774f0f4785d9cbe1b05d011c 477 PRINTS PR00149 Fumarate lyase superfamily signature 98 116 1.2E-9 T 29-03-2018 IPR000362 Fumarate lyase family SMALA_RS34670 8b1c7b33774f0f4785d9cbe1b05d011c 477 PRINTS PR00149 Fumarate lyase superfamily signature 143 161 1.2E-9 T 29-03-2018 IPR000362 Fumarate lyase family SMALA_RS34670 8b1c7b33774f0f4785d9cbe1b05d011c 477 PRINTS PR00149 Fumarate lyase superfamily signature 280 296 1.2E-9 T 29-03-2018 IPR000362 Fumarate lyase family SMALA_RS34670 8b1c7b33774f0f4785d9cbe1b05d011c 477 SMART SM00998 369 455 5.1E-20 T 29-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SMALA_RS34670 8b1c7b33774f0f4785d9cbe1b05d011c 477 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 11 455 3.5E-127 T 29-03-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SMALA_RS34670 8b1c7b33774f0f4785d9cbe1b05d011c 477 SUPERFAMILY SSF48557 10 456 1.15E-80 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 SMALA_RS34670 8b1c7b33774f0f4785d9cbe1b05d011c 477 Gene3D G3DSA:1.20.200.10 103 382 2.1E-56 T 29-03-2018 SMALA_RS34670 8b1c7b33774f0f4785d9cbe1b05d011c 477 Pfam PF10397 Adenylosuccinate lyase C-terminus 370 454 5.0E-12 T 29-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SMALA_RS34670 8b1c7b33774f0f4785d9cbe1b05d011c 477 Gene3D G3DSA:1.10.275.10 9 102 1.3E-14 T 29-03-2018 IPR024083 Fumarase/histidase, N-terminal SMALA_RS00690 03b96554e8288c5446347623928655b7 222 Gene3D G3DSA:2.160.10.20 95 179 1.7E-17 T 29-03-2018 SMALA_RS00690 03b96554e8288c5446347623928655b7 222 Gene3D G3DSA:2.160.10.20 19 94 3.3E-8 T 29-03-2018 SMALA_RS00690 03b96554e8288c5446347623928655b7 222 SUPERFAMILY SSF141571 34 206 1.67E-28 T 29-03-2018 SMALA_RS00690 03b96554e8288c5446347623928655b7 222 Pfam PF13599 Pentapeptide repeats (9 copies) 108 174 1.1E-10 T 29-03-2018 IPR001646 Pentapeptide repeat SMALA_RS28040 60607e9fbddb240bf3b9f7478bd58542 93 Pfam PF00708 Acylphosphatase 8 92 6.2E-22 T 29-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 SMALA_RS28040 60607e9fbddb240bf3b9f7478bd58542 93 SUPERFAMILY SSF54975 3 93 3.71E-24 T 29-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 SMALA_RS28040 60607e9fbddb240bf3b9f7478bd58542 93 Gene3D G3DSA:3.30.70.100 1 93 1.7E-27 T 29-03-2018 SMALA_RS28040 60607e9fbddb240bf3b9f7478bd58542 93 ProSitePatterns PS00150 Acylphosphatase signature 1. 11 21 - T 29-03-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 SMALA_RS03925 48d81672874af726b60811134d45729b 195 Pfam PF16157 Domain of unknown function (DUF4865) 1 182 7.9E-72 T 29-03-2018 IPR032349 Protein of unknown function DUF4865 SMALA_RS30160 44f033b2639461ad14ee527c6804bd3f 193 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 7 187 1.2E-24 T 29-03-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type SMALA_RS30160 44f033b2639461ad14ee527c6804bd3f 193 Gene3D G3DSA:1.20.120.450 4 137 8.0E-16 T 29-03-2018 SMALA_RS30160 44f033b2639461ad14ee527c6804bd3f 193 TIGRFAM TIGR03086 TIGR03086: TIGR03086 family protein 6 187 1.0E-50 T 29-03-2018 IPR017520 Conserved hypothetical protein CHP03086 SMALA_RS30160 44f033b2639461ad14ee527c6804bd3f 193 SUPERFAMILY SSF109854 5 137 1.98E-22 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes SMALA_RS30160 44f033b2639461ad14ee527c6804bd3f 193 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 6 131 3.2E-15 T 29-03-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 SMALA_RS37245 48193e43a6fd5a87542d430f3768051d 490 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 262 269 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 SMALA_RS37245 48193e43a6fd5a87542d430f3768051d 490 Gene3D G3DSA:3.40.309.10 281 472 1.1E-71 T 29-03-2018 SMALA_RS37245 48193e43a6fd5a87542d430f3768051d 490 Gene3D G3DSA:3.40.605.10 13 280 1.5E-95 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS37245 48193e43a6fd5a87542d430f3768051d 490 SUPERFAMILY SSF53720 16 488 3.53E-163 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMALA_RS37245 48193e43a6fd5a87542d430f3768051d 490 Pfam PF00171 Aldehyde dehydrogenase family 26 486 2.1E-162 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS09565 c893a16f44dc1504938d7ac8b2b197c9 75 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 3 71 2.1E-21 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 SMALA_RS09565 c893a16f44dc1504938d7ac8b2b197c9 75 PRINTS PR01651 Protein-export SecG membrane protein signature 36 52 3.8E-7 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 SMALA_RS09565 c893a16f44dc1504938d7ac8b2b197c9 75 PRINTS PR01651 Protein-export SecG membrane protein signature 1 21 3.8E-7 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 SMALA_RS09565 c893a16f44dc1504938d7ac8b2b197c9 75 PRINTS PR01651 Protein-export SecG membrane protein signature 52 74 3.8E-7 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 SMALA_RS09565 c893a16f44dc1504938d7ac8b2b197c9 75 PRINTS PR01651 Protein-export SecG membrane protein signature 21 35 3.8E-7 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 SMALA_RS09565 c893a16f44dc1504938d7ac8b2b197c9 75 Pfam PF03840 Preprotein translocase SecG subunit 3 71 1.7E-20 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 SMALA_RS15230 dc1f4a2ded097d8bc298abbf11d5df3e 242 Gene3D G3DSA:3.40.50.150 14 123 1.2E-4 T 29-03-2018 SMALA_RS15230 dc1f4a2ded097d8bc298abbf11d5df3e 242 SUPERFAMILY SSF53335 13 195 2.56E-7 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS38500 0ad00fe9baa7e0e0035d682cc9948a0f 287 Pfam PF04072 Leucine carboxyl methyltransferase 16 187 7.5E-54 T 29-03-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 SMALA_RS38500 0ad00fe9baa7e0e0035d682cc9948a0f 287 SUPERFAMILY SSF53335 11 275 2.41E-69 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS38500 0ad00fe9baa7e0e0035d682cc9948a0f 287 Gene3D G3DSA:3.40.50.150 7 267 1.2E-54 T 29-03-2018 SMALA_RS38500 0ad00fe9baa7e0e0035d682cc9948a0f 287 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 13 265 1.3E-81 T 29-03-2018 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 SMALA_RS42675 fa5933c97df6ef6cefe7a208669d3647 438 Gene3D G3DSA:3.50.50.60 122 255 1.8E-26 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS42675 fa5933c97df6ef6cefe7a208669d3647 438 Gene3D G3DSA:3.30.390.30 347 428 1.8E-23 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SMALA_RS42675 fa5933c97df6ef6cefe7a208669d3647 438 Gene3D G3DSA:3.50.50.60 2 121 1.0E-15 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS42675 fa5933c97df6ef6cefe7a208669d3647 438 SUPERFAMILY SSF51905 161 327 6.91E-28 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS42675 fa5933c97df6ef6cefe7a208669d3647 438 SUPERFAMILY SSF55424 329 423 1.79E-23 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SMALA_RS42675 fa5933c97df6ef6cefe7a208669d3647 438 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 273 295 7.0E-20 T 29-03-2018 SMALA_RS42675 fa5933c97df6ef6cefe7a208669d3647 438 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 161 179 7.0E-20 T 29-03-2018 SMALA_RS42675 fa5933c97df6ef6cefe7a208669d3647 438 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 247 263 7.0E-20 T 29-03-2018 SMALA_RS42675 fa5933c97df6ef6cefe7a208669d3647 438 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 21 40 7.0E-20 T 29-03-2018 SMALA_RS42675 fa5933c97df6ef6cefe7a208669d3647 438 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 116 134 7.0E-20 T 29-03-2018 SMALA_RS42675 fa5933c97df6ef6cefe7a208669d3647 438 Gene3D G3DSA:3.50.50.60 260 346 3.9E-5 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS42675 fa5933c97df6ef6cefe7a208669d3647 438 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 20 42 9.5E-14 T 29-03-2018 SMALA_RS42675 fa5933c97df6ef6cefe7a208669d3647 438 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 161 186 9.5E-14 T 29-03-2018 SMALA_RS42675 fa5933c97df6ef6cefe7a208669d3647 438 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 288 295 9.5E-14 T 29-03-2018 SMALA_RS42675 fa5933c97df6ef6cefe7a208669d3647 438 Pfam PF14759 Reductase C-terminal 337 421 2.1E-19 T 29-03-2018 IPR028202 Reductase, C-terminal SMALA_RS42675 fa5933c97df6ef6cefe7a208669d3647 438 SUPERFAMILY SSF51905 20 206 1.11E-42 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS42675 fa5933c97df6ef6cefe7a208669d3647 438 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 20 318 7.2E-56 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS13225 0c71c21deaa84ecf6ffd74e709069add 218 PRINTS PR00127 Clp protease catalytic subunit P signature 36 51 1.2E-41 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMALA_RS13225 0c71c21deaa84ecf6ffd74e709069add 218 PRINTS PR00127 Clp protease catalytic subunit P signature 186 205 1.2E-41 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMALA_RS13225 0c71c21deaa84ecf6ffd74e709069add 218 PRINTS PR00127 Clp protease catalytic subunit P signature 128 147 1.2E-41 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMALA_RS13225 0c71c21deaa84ecf6ffd74e709069add 218 PRINTS PR00127 Clp protease catalytic subunit P signature 76 96 1.2E-41 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMALA_RS13225 0c71c21deaa84ecf6ffd74e709069add 218 PRINTS PR00127 Clp protease catalytic subunit P signature 107 124 1.2E-41 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMALA_RS13225 0c71c21deaa84ecf6ffd74e709069add 218 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 129 142 - T 29-03-2018 IPR033135 ClpP, histidine active site SMALA_RS13225 0c71c21deaa84ecf6ffd74e709069add 218 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 107 118 - T 29-03-2018 IPR018215 ClpP, Ser active site SMALA_RS13225 0c71c21deaa84ecf6ffd74e709069add 218 SUPERFAMILY SSF52096 28 212 3.4E-61 T 29-03-2018 IPR029045 ClpP/crotonase-like domain SMALA_RS13225 0c71c21deaa84ecf6ffd74e709069add 218 Pfam PF00574 Clp protease 30 210 1.5E-75 T 29-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA SMALA_RS13225 0c71c21deaa84ecf6ffd74e709069add 218 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 20 211 39.224 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMALA_RS13225 0c71c21deaa84ecf6ffd74e709069add 218 Gene3D G3DSA:3.90.226.10 19 212 3.7E-37 T 29-03-2018 SMALA_RS38230 fe11758e8e8b3518ea937ae48ec87deb 318 SUPERFAMILY SSF47203 90 202 2.9E-9 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMALA_RS38230 fe11758e8e8b3518ea937ae48ec87deb 318 Gene3D G3DSA:1.20.140.10 86 220 2.2E-8 T 29-03-2018 SMALA_RS22065 00289c95a51dfc11983d2bb35e7859a9 601 Gene3D G3DSA:3.30.200.20 6 107 9.8E-12 T 29-03-2018 SMALA_RS22065 00289c95a51dfc11983d2bb35e7859a9 601 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 21 43 - T 29-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 SMALA_RS22065 00289c95a51dfc11983d2bb35e7859a9 601 SMART SM00220 15 266 5.7E-48 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMALA_RS22065 00289c95a51dfc11983d2bb35e7859a9 601 Pfam PF00069 Protein kinase domain 15 263 2.6E-39 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMALA_RS22065 00289c95a51dfc11983d2bb35e7859a9 601 SUPERFAMILY SSF56112 11 355 7.99E-67 T 29-03-2018 IPR011009 Protein kinase-like domain SMALA_RS22065 00289c95a51dfc11983d2bb35e7859a9 601 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 133 145 - T 29-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMALA_RS22065 00289c95a51dfc11983d2bb35e7859a9 601 Gene3D G3DSA:1.10.510.10 108 272 1.0E-45 T 29-03-2018 SMALA_RS20120 e0f55c7199f7a82fe7907d8b731d980c 328 PIRSF PIRSF006232 22 318 2.3E-90 T 29-03-2018 IPR012093 Pirin Reactome: R-HSA-8935690 SMALA_RS20120 e0f55c7199f7a82fe7907d8b731d980c 328 SUPERFAMILY SSF51182 25 317 2.39E-81 T 29-03-2018 IPR011051 RmlC-like cupin domain SMALA_RS20120 e0f55c7199f7a82fe7907d8b731d980c 328 Pfam PF05726 Pirin C-terminal cupin domain 201 309 3.0E-32 T 29-03-2018 IPR008778 Pirin, C-terminal domain Reactome: R-HSA-8935690 SMALA_RS20120 e0f55c7199f7a82fe7907d8b731d980c 328 Gene3D G3DSA:2.60.120.10 20 283 8.3E-77 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SMALA_RS20120 e0f55c7199f7a82fe7907d8b731d980c 328 Pfam PF02678 Pirin 42 146 1.6E-30 T 29-03-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 SMALA_RS40185 2463b55c08b2d93117972e4c964cc6d3 367 SMART SM00829 9 360 0.0071 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS40185 2463b55c08b2d93117972e4c964cc6d3 367 Pfam PF00107 Zinc-binding dehydrogenase 198 287 5.7E-16 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMALA_RS40185 2463b55c08b2d93117972e4c964cc6d3 367 SUPERFAMILY SSF51735 160 326 1.47E-31 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS40185 2463b55c08b2d93117972e4c964cc6d3 367 Gene3D G3DSA:3.90.180.10 292 364 0.02 T 29-03-2018 SMALA_RS40185 2463b55c08b2d93117972e4c964cc6d3 367 Gene3D G3DSA:3.40.50.10730 184 291 1.9E-25 T 29-03-2018 SMALA_RS40185 2463b55c08b2d93117972e4c964cc6d3 367 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 155 1.6E-20 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS40185 2463b55c08b2d93117972e4c964cc6d3 367 SUPERFAMILY SSF50129 2 194 2.89E-49 T 29-03-2018 IPR011032 GroES-like SMALA_RS40185 2463b55c08b2d93117972e4c964cc6d3 367 Gene3D G3DSA:3.90.180.10 1 183 3.2E-42 T 29-03-2018 SMALA_RS17070 b3335ccfc8de2332c4d9b343314d0bcd 452 Pfam PF00561 alpha/beta hydrolase fold 65 212 4.8E-18 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS17070 b3335ccfc8de2332c4d9b343314d0bcd 452 Gene3D G3DSA:3.40.50.1820 40 447 5.4E-31 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS17070 b3335ccfc8de2332c4d9b343314d0bcd 452 SUPERFAMILY SSF53474 29 251 2.89E-29 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS17070 b3335ccfc8de2332c4d9b343314d0bcd 452 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 67 75 2.9E-9 T 29-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 SMALA_RS17070 b3335ccfc8de2332c4d9b343314d0bcd 452 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 97 108 2.9E-9 T 29-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 SMALA_RS17070 b3335ccfc8de2332c4d9b343314d0bcd 452 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 156 170 2.9E-9 T 29-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 SMALA_RS06235 f72387e060c6917bfd5e0a1e28aa8210 282 SMART SM00382 27 212 1.6E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS06235 f72387e060c6917bfd5e0a1e28aa8210 282 SUPERFAMILY SSF52540 3 223 1.03E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS06235 f72387e060c6917bfd5e0a1e28aa8210 282 Gene3D G3DSA:3.40.50.300 2 247 4.4E-56 T 29-03-2018 SMALA_RS06235 f72387e060c6917bfd5e0a1e28aa8210 282 Pfam PF00005 ABC transporter 18 168 1.3E-26 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS06235 f72387e060c6917bfd5e0a1e28aa8210 282 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS35155 6f483be83bbe0564cfdd8afcbb84d587 285 Gene3D G3DSA:3.40.1130.10 44 267 4.0E-22 T 29-03-2018 SMALA_RS35155 6f483be83bbe0564cfdd8afcbb84d587 285 Pfam PF01553 Acyltransferase 80 203 7.6E-18 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SMALA_RS35155 6f483be83bbe0564cfdd8afcbb84d587 285 SUPERFAMILY SSF69593 90 208 1.31E-19 T 29-03-2018 SMALA_RS35155 6f483be83bbe0564cfdd8afcbb84d587 285 SMART SM00563 95 207 1.7E-23 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SMALA_RS25725 2966cb615a6b82c07d33e362b4a18ae9 247 PIRSF PIRSF006648 2 245 5.1E-16 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMALA_RS25725 2966cb615a6b82c07d33e362b4a18ae9 247 Pfam PF12698 ABC-2 family transporter protein 53 239 5.8E-12 T 29-03-2018 SMALA_RS15170 72bfbd02accb002b81632eadc67adc60 65 SUPERFAMILY SSF47598 1 47 8.26E-8 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 SMALA_RS15170 72bfbd02accb002b81632eadc67adc60 65 Gene3D G3DSA:1.10.1220.10 1 41 8.8E-9 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 SMALA_RS15170 72bfbd02accb002b81632eadc67adc60 65 Pfam PF03869 Arc-like DNA binding domain 4 42 1.5E-5 T 29-03-2018 IPR005569 Arc-like DNA binding domain GO:0003677 SMALA_RS32130 23d476004e059ec7e5268ccac0730b0d 650 SUPERFAMILY SSF52518 310 478 4.37E-50 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold SMALA_RS32130 23d476004e059ec7e5268ccac0730b0d 650 SUPERFAMILY SSF52518 2 346 2.24E-69 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold SMALA_RS32130 23d476004e059ec7e5268ccac0730b0d 650 Gene3D G3DSA:3.40.50.920 489 619 2.5E-32 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMALA_RS32130 23d476004e059ec7e5268ccac0730b0d 650 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 3 618 40.93 T 29-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SMALA_RS32130 23d476004e059ec7e5268ccac0730b0d 650 ProSitePatterns PS00801 Transketolase signature 1. 29 48 - T 29-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SMALA_RS32130 23d476004e059ec7e5268ccac0730b0d 650 SUPERFAMILY SSF52922 488 616 7.85E-29 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMALA_RS32130 23d476004e059ec7e5268ccac0730b0d 650 Pfam PF02780 Transketolase, C-terminal domain 491 609 9.5E-31 T 29-03-2018 IPR033248 Transketolase, C-terminal domain SMALA_RS32130 23d476004e059ec7e5268ccac0730b0d 650 SMART SM00861 316 480 1.9E-47 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain SMALA_RS32130 23d476004e059ec7e5268ccac0730b0d 650 Gene3D G3DSA:3.40.50.970 307 484 1.2E-38 T 29-03-2018 SMALA_RS32130 23d476004e059ec7e5268ccac0730b0d 650 ProSitePatterns PS00802 Transketolase signature 2. 422 438 - T 29-03-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SMALA_RS32130 23d476004e059ec7e5268ccac0730b0d 650 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 4 279 6.7E-109 T 29-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SMALA_RS32130 23d476004e059ec7e5268ccac0730b0d 650 Pfam PF02779 Transketolase, pyrimidine binding domain 317 479 1.9E-35 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain SMALA_RS32130 23d476004e059ec7e5268ccac0730b0d 650 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 6 617 3.9E-184 T 29-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SMALA_RS32130 23d476004e059ec7e5268ccac0730b0d 650 Gene3D G3DSA:3.40.50.970 1 306 2.5E-78 T 29-03-2018 SMALA_RS02820 aaf1dd92cde699e32267042cde2b6e44 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 63 1.7E-17 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS02820 aaf1dd92cde699e32267042cde2b6e44 300 SUPERFAMILY SSF46785 6 102 6.31E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS02820 aaf1dd92cde699e32267042cde2b6e44 300 Gene3D G3DSA:1.10.10.10 4 87 8.7E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS13275 bb008af2baed60ad54aa730cc54bd8c5 410 SUPERFAMILY SSF55718 305 410 3.92E-26 T 29-03-2018 IPR003033 SCP2 sterol-binding domain SMALA_RS13275 bb008af2baed60ad54aa730cc54bd8c5 410 Pfam PF13527 Acetyltransferase (GNAT) domain 5 131 1.5E-30 T 29-03-2018 SMALA_RS13275 bb008af2baed60ad54aa730cc54bd8c5 410 Gene3D G3DSA:3.40.630.30 1 97 8.5E-11 T 29-03-2018 SMALA_RS13275 bb008af2baed60ad54aa730cc54bd8c5 410 SUPERFAMILY SSF55729 4 304 1.01E-53 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS13275 bb008af2baed60ad54aa730cc54bd8c5 410 Pfam PF13530 Sterol carrier protein domain 182 407 7.6E-49 T 29-03-2018 IPR025559 Enhanced intracellular survival protein domain SMALA_RS13275 bb008af2baed60ad54aa730cc54bd8c5 410 Gene3D G3DSA:3.40.630.30 123 294 2.5E-42 T 29-03-2018 SMALA_RS13275 bb008af2baed60ad54aa730cc54bd8c5 410 Gene3D G3DSA:3.30.1050.10 295 403 4.8E-34 T 29-03-2018 IPR003033 SCP2 sterol-binding domain SMALA_RS13275 bb008af2baed60ad54aa730cc54bd8c5 410 Hamap MF_01812 UPF0256 protein . 2 410 34.195 T 29-03-2018 IPR022902 N-acetyltransferase Eis SMALA_RS29960 5c361525c40e0c0fe7e17163aa6b5ac8 207 Gene3D G3DSA:3.90.550.10 2 175 1.0E-17 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS29960 5c361525c40e0c0fe7e17163aa6b5ac8 207 Pfam PF09837 Uncharacterized protein conserved in bacteria (DUF2064) 40 149 2.6E-22 T 29-03-2018 IPR018641 Transferase 1, rSAM/selenodomain-associated SMALA_RS29960 5c361525c40e0c0fe7e17163aa6b5ac8 207 SUPERFAMILY SSF53448 3 188 2.81E-29 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS15630 d915cb527a1570132b4ec1473aef7f2b 222 Pfam PF13242 HAD-hyrolase-like 145 212 1.6E-9 T 29-03-2018 SMALA_RS15630 d915cb527a1570132b4ec1473aef7f2b 222 Gene3D G3DSA:1.10.150.240 24 76 2.9E-4 T 29-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 SMALA_RS15630 d915cb527a1570132b4ec1473aef7f2b 222 SUPERFAMILY SSF56784 7 213 4.28E-32 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS15630 d915cb527a1570132b4ec1473aef7f2b 222 Gene3D G3DSA:3.40.50.1000 77 222 2.0E-17 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS40955 acb3a6d97ea7b92fda8b911d26e4ab66 144 Gene3D G3DSA:3.10.129.10 5 137 4.1E-23 T 29-03-2018 SMALA_RS40955 acb3a6d97ea7b92fda8b911d26e4ab66 144 SUPERFAMILY SSF54637 23 118 2.99E-17 T 29-03-2018 IPR029069 HotDog domain SMALA_RS40955 acb3a6d97ea7b92fda8b911d26e4ab66 144 Pfam PF07977 FabA-like domain 9 105 4.8E-10 T 29-03-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 SMALA_RS27715 239686a8280f4abdf5847b216ae5ee07 616 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 218 353 1.8E-47 T 29-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 SMALA_RS27715 239686a8280f4abdf5847b216ae5ee07 616 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 417 578 5.5E-47 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 SMALA_RS27715 239686a8280f4abdf5847b216ae5ee07 616 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 29 194 4.4E-55 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 SMALA_RS27715 239686a8280f4abdf5847b216ae5ee07 616 SUPERFAMILY SSF52518 394 606 5.54E-67 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold SMALA_RS27715 239686a8280f4abdf5847b216ae5ee07 616 SUPERFAMILY SSF52467 210 385 1.35E-62 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain SMALA_RS27715 239686a8280f4abdf5847b216ae5ee07 616 SUPERFAMILY SSF52518 27 207 7.66E-61 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold SMALA_RS27715 239686a8280f4abdf5847b216ae5ee07 616 Gene3D G3DSA:3.40.50.970 378 599 1.7E-51 T 29-03-2018 SMALA_RS27715 239686a8280f4abdf5847b216ae5ee07 616 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 29 602 1.5E-231 T 29-03-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 SMALA_RS27715 239686a8280f4abdf5847b216ae5ee07 616 Gene3D G3DSA:3.40.50.1220 223 377 3.3E-56 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain SMALA_RS27715 239686a8280f4abdf5847b216ae5ee07 616 Gene3D G3DSA:3.40.50.970 22 222 2.3E-59 T 29-03-2018 SMALA_RS20630 f58b6373a3beacd0324d1ab76e571c89 501 Gene3D G3DSA:2.130.10.130 17 129 1.4E-8 T 29-03-2018 SMALA_RS20630 f58b6373a3beacd0324d1ab76e571c89 501 Gene3D G3DSA:2.130.10.130 301 476 1.5E-14 T 29-03-2018 SMALA_RS20630 f58b6373a3beacd0324d1ab76e571c89 501 SUPERFAMILY SSF69318 122 462 1.05E-22 T 29-03-2018 SMALA_RS20630 f58b6373a3beacd0324d1ab76e571c89 501 Gene3D G3DSA:2.60.40.680 130 215 2.7E-6 T 29-03-2018 SMALA_RS20630 f58b6373a3beacd0324d1ab76e571c89 501 SUPERFAMILY SSF69318 56 139 1.83E-9 T 29-03-2018 SMALA_RS20630 f58b6373a3beacd0324d1ab76e571c89 501 Pfam PF01839 FG-GAP repeat 120 142 3.1E-5 T 29-03-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 SMALA_RS42835 519ff5030e0840fe96fd98c48ba8d5b3 365 SUPERFAMILY SSF48576 31 359 1.78E-64 T 29-03-2018 IPR008949 Isoprenoid synthase domain SMALA_RS42835 519ff5030e0840fe96fd98c48ba8d5b3 365 Gene3D G3DSA:1.10.600.10 20 364 1.2E-79 T 29-03-2018 IPR008949 Isoprenoid synthase domain SMALA_RS42835 519ff5030e0840fe96fd98c48ba8d5b3 365 Pfam PF00348 Polyprenyl synthetase 60 309 2.5E-41 T 29-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 SMALA_RS42835 519ff5030e0840fe96fd98c48ba8d5b3 365 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 243 255 - T 29-03-2018 IPR033749 Polyprenyl synthetase, conserved site SMALA_RS19255 a65f0fd5e5fa36371138d52037eac150 224 SMART SM00943 25 198 3.2E-19 T 29-03-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal SMALA_RS19255 a65f0fd5e5fa36371138d52037eac150 224 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 25 189 1.1E-17 T 29-03-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal SMALA_RS25485 339871a035e7b5ea206e09cd926238ca 378 Gene3D G3DSA:3.90.550.10 68 323 1.3E-51 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS25485 339871a035e7b5ea206e09cd926238ca 378 SUPERFAMILY SSF53448 92 319 2.72E-52 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS25485 339871a035e7b5ea206e09cd926238ca 378 Pfam PF00535 Glycosyl transferase family 2 95 216 4.3E-26 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 SMALA_RS01895 10cd3ecd3bac900af1c939d3596aa3c3 534 Pfam PF13520 Amino acid permease 26 417 2.0E-37 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMALA_RS01895 10cd3ecd3bac900af1c939d3596aa3c3 534 PIRSF PIRSF006060 14 458 1.5E-59 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMALA_RS01895 10cd3ecd3bac900af1c939d3596aa3c3 534 PIRSF PIRSF006060 441 526 120.0 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMALA_RS02770 7c7b0b4e3f69687afa61358b99b091b2 71 Gene3D G3DSA:3.30.429.10 1 62 1.7E-17 T 29-03-2018 SMALA_RS02770 7c7b0b4e3f69687afa61358b99b091b2 71 Pfam PF01361 Tautomerase enzyme 2 61 2.3E-17 T 29-03-2018 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 SMALA_RS02770 7c7b0b4e3f69687afa61358b99b091b2 71 SUPERFAMILY SSF55331 2 63 1.02E-11 T 29-03-2018 IPR014347 Tautomerase/MIF superfamily SMALA_RS24670 593c26b8cfe4de2183d5abb67855e375 253 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 198 215 - T 29-03-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199 SMALA_RS24670 593c26b8cfe4de2183d5abb67855e375 253 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 24 253 35.996 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 SMALA_RS24670 593c26b8cfe4de2183d5abb67855e375 253 SUPERFAMILY SSF64005 19 247 1.7E-73 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 SMALA_RS24670 593c26b8cfe4de2183d5abb67855e375 253 Pfam PF01255 Putative undecaprenyl diphosphate synthase 31 252 1.2E-70 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 SMALA_RS24670 593c26b8cfe4de2183d5abb67855e375 253 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 24 252 5.3E-65 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 SMALA_RS24670 593c26b8cfe4de2183d5abb67855e375 253 Gene3D G3DSA:3.40.1180.10 10 253 9.0E-84 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 SMALA_RS22350 4b1e80dd5ac08322b2e8f0f0e0ba6645 151 SUPERFAMILY SSF81330 10 105 2.22E-18 T 29-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 SMALA_RS22350 4b1e80dd5ac08322b2e8f0f0e0ba6645 151 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 2 101 4.9E-23 T 29-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 SMALA_RS19045 89fa4a8c9ffdb6882556522a0e798938 294 Gene3D G3DSA:3.40.50.620 146 294 1.2E-22 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS19045 89fa4a8c9ffdb6882556522a0e798938 294 SUPERFAMILY SSF52402 156 292 6.87E-22 T 29-03-2018 SMALA_RS19045 89fa4a8c9ffdb6882556522a0e798938 294 Gene3D G3DSA:3.40.50.620 2 145 1.8E-30 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS19045 89fa4a8c9ffdb6882556522a0e798938 294 Pfam PF00582 Universal stress protein family 156 290 5.2E-14 T 29-03-2018 IPR006016 UspA GO:0006950 SMALA_RS19045 89fa4a8c9ffdb6882556522a0e798938 294 Pfam PF00582 Universal stress protein family 4 136 3.9E-23 T 29-03-2018 IPR006016 UspA GO:0006950 SMALA_RS19045 89fa4a8c9ffdb6882556522a0e798938 294 SUPERFAMILY SSF52402 4 137 1.84E-27 T 29-03-2018 SMALA_RS19045 89fa4a8c9ffdb6882556522a0e798938 294 PRINTS PR01438 Universal stress protein signature 268 290 8.3E-11 T 29-03-2018 IPR006015 Universal stress protein A SMALA_RS19045 89fa4a8c9ffdb6882556522a0e798938 294 PRINTS PR01438 Universal stress protein signature 2 20 8.3E-11 T 29-03-2018 IPR006015 Universal stress protein A SMALA_RS19045 89fa4a8c9ffdb6882556522a0e798938 294 PRINTS PR01438 Universal stress protein signature 250 262 8.3E-11 T 29-03-2018 IPR006015 Universal stress protein A SMALA_RS03650 5d20e81c1951f7eb3a624bcaa6ed014e 975 SUPERFAMILY SSF46894 893 951 6.8E-5 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS03650 5d20e81c1951f7eb3a624bcaa6ed014e 975 Gene3D G3DSA:1.25.40.10 524 713 3.4E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS03650 5d20e81c1951f7eb3a624bcaa6ed014e 975 Gene3D G3DSA:1.25.40.10 719 895 2.7E-4 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS03650 5d20e81c1951f7eb3a624bcaa6ed014e 975 SUPERFAMILY SSF52540 10 107 1.32E-10 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS03650 5d20e81c1951f7eb3a624bcaa6ed014e 975 SUPERFAMILY SSF52540 153 265 1.32E-10 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS03650 5d20e81c1951f7eb3a624bcaa6ed014e 975 Gene3D G3DSA:1.25.40.10 412 523 2.8E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS03650 5d20e81c1951f7eb3a624bcaa6ed014e 975 Pfam PF13191 AAA ATPase domain 11 187 4.8E-18 T 29-03-2018 SMALA_RS03650 5d20e81c1951f7eb3a624bcaa6ed014e 975 SUPERFAMILY SSF48452 606 709 8.93E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS03650 5d20e81c1951f7eb3a624bcaa6ed014e 975 SUPERFAMILY SSF48452 491 521 8.93E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS03650 5d20e81c1951f7eb3a624bcaa6ed014e 975 Gene3D G3DSA:3.40.50.300 11 206 3.9E-9 T 29-03-2018 SMALA_RS03650 5d20e81c1951f7eb3a624bcaa6ed014e 975 Gene3D G3DSA:1.10.10.10 896 962 7.5E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS11405 1da24ea2b33317ee6d67d396bb3f0a1b 336 SUPERFAMILY SSF51679 1 332 7.95E-56 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS11405 1da24ea2b33317ee6d67d396bb3f0a1b 336 Pfam PF00296 Luciferase-like monooxygenase 19 314 1.4E-60 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS11405 1da24ea2b33317ee6d67d396bb3f0a1b 336 TIGRFAM TIGR03559 F420_Rv3520c: probable F420-dependent oxidoreductase, Rv3520c family 2 319 6.3E-131 T 29-03-2018 IPR019951 F420-dependent oxidoreductase-predicted, Rv3520c SMALA_RS11405 1da24ea2b33317ee6d67d396bb3f0a1b 336 Gene3D G3DSA:3.20.20.30 16 336 2.1E-58 T 29-03-2018 SMALA_RS26960 47101e22fe06304a2668bd1a73982ffd 260 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS26960 47101e22fe06304a2668bd1a73982ffd 260 Gene3D G3DSA:3.40.50.300 1 246 7.8E-71 T 29-03-2018 SMALA_RS26960 47101e22fe06304a2668bd1a73982ffd 260 SUPERFAMILY SSF52540 3 228 1.84E-64 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS26960 47101e22fe06304a2668bd1a73982ffd 260 Pfam PF00005 ABC transporter 24 166 1.5E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS26960 47101e22fe06304a2668bd1a73982ffd 260 SMART SM00382 32 216 1.4E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS31820 53579d0ed534ecdcb1c15d1d45e98f27 344 SMART SM00382 31 234 6.4E-18 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS31820 53579d0ed534ecdcb1c15d1d45e98f27 344 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 235 304 2.4E-18 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMALA_RS31820 53579d0ed534ecdcb1c15d1d45e98f27 344 SUPERFAMILY SSF52540 2 255 3.01E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS31820 53579d0ed534ecdcb1c15d1d45e98f27 344 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS31820 53579d0ed534ecdcb1c15d1d45e98f27 344 Gene3D G3DSA:3.40.50.300 1 307 4.0E-67 T 29-03-2018 SMALA_RS31820 53579d0ed534ecdcb1c15d1d45e98f27 344 Pfam PF00005 ABC transporter 22 180 1.6E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS31820 53579d0ed534ecdcb1c15d1d45e98f27 344 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 236 299 1.5E-16 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMALA_RS20670 3ca99d4d8b0101076ec2014fa9c88058 123 SUPERFAMILY SSF51182 15 106 1.33E-7 T 29-03-2018 IPR011051 RmlC-like cupin domain SMALA_RS20670 3ca99d4d8b0101076ec2014fa9c88058 123 Gene3D G3DSA:2.60.120.10 2 122 1.6E-11 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SMALA_RS10760 44e4688ca2237dc45cbe4e23e31f705b 212 Pfam PF01810 LysE type translocator 17 207 3.3E-27 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 SMALA_RS10760 44e4688ca2237dc45cbe4e23e31f705b 212 PIRSF PIRSF006324 1 210 1.6E-52 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 SMALA_RS36900 045ec70cc633239ac1643c56bd1e3e7e 197 SUPERFAMILY SSF47741 96 186 8.64E-26 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 SMALA_RS36900 045ec70cc633239ac1643c56bd1e3e7e 197 Gene3D G3DSA:3.10.20.30 7 83 2.0E-25 T 29-03-2018 IPR012675 Beta-grasp domain SMALA_RS36900 045ec70cc633239ac1643c56bd1e3e7e 197 Pfam PF01799 [2Fe-2S] binding domain 83 176 1.4E-25 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 SMALA_RS36900 045ec70cc633239ac1643c56bd1e3e7e 197 Gene3D G3DSA:1.10.150.120 84 195 1.5E-30 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 SMALA_RS36900 045ec70cc633239ac1643c56bd1e3e7e 197 SUPERFAMILY SSF54292 11 87 2.23E-24 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SMALA_RS36900 045ec70cc633239ac1643c56bd1e3e7e 197 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 16 63 3.4E-8 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SMALA_RS36900 045ec70cc633239ac1643c56bd1e3e7e 197 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 48 56 - T 29-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 SMALA_RS35765 3bdb0fe8ef8d8086b2b07f0359392960 474 Pfam PF00672 HAMP domain 200 248 1.5E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMALA_RS35765 3bdb0fe8ef8d8086b2b07f0359392960 474 SUPERFAMILY SSF47384 236 316 7.46E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS35765 3bdb0fe8ef8d8086b2b07f0359392960 474 SMART SM00387 360 467 7.2E-24 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS35765 3bdb0fe8ef8d8086b2b07f0359392960 474 SUPERFAMILY SSF158472 200 249 1.11E-6 T 29-03-2018 SMALA_RS35765 3bdb0fe8ef8d8086b2b07f0359392960 474 Pfam PF00512 His Kinase A (phospho-acceptor) domain 254 315 3.4E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS35765 3bdb0fe8ef8d8086b2b07f0359392960 474 Gene3D G3DSA:3.30.565.10 323 464 7.8E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS35765 3bdb0fe8ef8d8086b2b07f0359392960 474 Gene3D G3DSA:1.10.287.130 243 315 5.9E-11 T 29-03-2018 SMALA_RS35765 3bdb0fe8ef8d8086b2b07f0359392960 474 SMART SM00304 199 252 9.2E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMALA_RS35765 3bdb0fe8ef8d8086b2b07f0359392960 474 PRINTS PR00344 Bacterial sensor protein C-terminal signature 427 445 1.1E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS35765 3bdb0fe8ef8d8086b2b07f0359392960 474 PRINTS PR00344 Bacterial sensor protein C-terminal signature 412 422 1.1E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS35765 3bdb0fe8ef8d8086b2b07f0359392960 474 PRINTS PR00344 Bacterial sensor protein C-terminal signature 394 408 1.1E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS35765 3bdb0fe8ef8d8086b2b07f0359392960 474 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 362 462 6.8E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS35765 3bdb0fe8ef8d8086b2b07f0359392960 474 SUPERFAMILY SSF55874 319 462 2.23E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS35765 3bdb0fe8ef8d8086b2b07f0359392960 474 SMART SM00388 253 320 3.8E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS12595 bf4b1c7290b59070708c2db45ca5af3b 503 SMART SM00388 281 346 4.7E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS12595 bf4b1c7290b59070708c2db45ca5af3b 503 SUPERFAMILY SSF47384 264 345 8.04E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS12595 bf4b1c7290b59070708c2db45ca5af3b 503 SMART SM00304 227 280 0.0035 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMALA_RS12595 bf4b1c7290b59070708c2db45ca5af3b 503 Pfam PF00512 His Kinase A (phospho-acceptor) domain 282 345 1.0E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS12595 bf4b1c7290b59070708c2db45ca5af3b 503 PRINTS PR00344 Bacterial sensor protein C-terminal signature 424 438 3.4E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS12595 bf4b1c7290b59070708c2db45ca5af3b 503 PRINTS PR00344 Bacterial sensor protein C-terminal signature 459 477 3.4E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS12595 bf4b1c7290b59070708c2db45ca5af3b 503 PRINTS PR00344 Bacterial sensor protein C-terminal signature 442 452 3.4E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS12595 bf4b1c7290b59070708c2db45ca5af3b 503 PRINTS PR00344 Bacterial sensor protein C-terminal signature 482 495 3.4E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS12595 bf4b1c7290b59070708c2db45ca5af3b 503 SUPERFAMILY SSF55874 335 498 2.36E-38 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS12595 bf4b1c7290b59070708c2db45ca5af3b 503 Gene3D G3DSA:1.10.287.130 271 342 3.3E-13 T 29-03-2018 SMALA_RS12595 bf4b1c7290b59070708c2db45ca5af3b 503 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 391 496 2.8E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS12595 bf4b1c7290b59070708c2db45ca5af3b 503 Gene3D G3DSA:3.30.565.10 350 503 3.5E-35 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS12595 bf4b1c7290b59070708c2db45ca5af3b 503 SMART SM00387 389 498 1.2E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS17085 6c793e01f2f3c9ff9eff755f14bbbc6c 466 Pfam PF07730 Histidine kinase 209 272 3.6E-14 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMALA_RS17085 6c793e01f2f3c9ff9eff755f14bbbc6c 466 SUPERFAMILY SSF55874 399 456 7.18E-7 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS17085 6c793e01f2f3c9ff9eff755f14bbbc6c 466 SUPERFAMILY SSF55874 294 349 7.18E-7 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS17085 6c793e01f2f3c9ff9eff755f14bbbc6c 466 Gene3D G3DSA:3.30.565.10 274 463 1.3E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS14560 d59d6c3c81dc325a7cd3cd71626a48a5 361 Gene3D G3DSA:3.20.20.30 11 352 2.0E-77 T 29-03-2018 SMALA_RS14560 d59d6c3c81dc325a7cd3cd71626a48a5 361 SUPERFAMILY SSF51679 12 350 3.77E-80 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS14560 d59d6c3c81dc325a7cd3cd71626a48a5 361 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 13 351 1.5E-126 T 29-03-2018 IPR019949 Luciferase family oxidoreductase, group 1 SMALA_RS14560 d59d6c3c81dc325a7cd3cd71626a48a5 361 Pfam PF00296 Luciferase-like monooxygenase 14 327 7.2E-42 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS28450 ef9461443089bc0dc89f5920e9f3fc05 167 Gene3D G3DSA:1.20.1260.10 11 139 4.9E-13 T 29-03-2018 IPR012347 Ferritin-related SMALA_RS28450 ef9461443089bc0dc89f5920e9f3fc05 167 Pfam PF14530 Domain of unknown function (DUF4439) 19 149 1.6E-45 T 29-03-2018 IPR029447 Domain of unknown function DUF4439 SMALA_RS28450 ef9461443089bc0dc89f5920e9f3fc05 167 SUPERFAMILY SSF47240 15 149 3.02E-37 T 29-03-2018 IPR009078 Ferritin-like superfamily SMALA_RS35595 18017c7c033c1c5bd293c9e454ff2927 416 SUPERFAMILY SSF103473 13 396 2.49E-32 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS35595 18017c7c033c1c5bd293c9e454ff2927 416 Pfam PF07690 Major Facilitator Superfamily 19 356 4.5E-17 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS35595 18017c7c033c1c5bd293c9e454ff2927 416 Gene3D G3DSA:1.20.1250.20 213 404 1.0E-11 T 29-03-2018 SMALA_RS35595 18017c7c033c1c5bd293c9e454ff2927 416 Gene3D G3DSA:1.20.1250.20 6 192 9.8E-15 T 29-03-2018 SMALA_RS40530 b3ab236d58239f3fbf32c0766da065fa 547 Gene3D G3DSA:3.40.309.10 290 469 9.6E-16 T 29-03-2018 SMALA_RS40530 b3ab236d58239f3fbf32c0766da065fa 547 SUPERFAMILY SSF53720 31 531 1.44E-97 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMALA_RS40530 b3ab236d58239f3fbf32c0766da065fa 547 Pfam PF00171 Aldehyde dehydrogenase family 31 340 2.6E-45 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS40530 b3ab236d58239f3fbf32c0766da065fa 547 Gene3D G3DSA:3.40.605.10 9 289 6.1E-55 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS14595 9f1195b363db710cfee0ea3ca3cceab0 472 Pfam PF01425 Amidase 25 452 1.2E-102 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMALA_RS14595 9f1195b363db710cfee0ea3ca3cceab0 472 SUPERFAMILY SSF75304 2 458 5.49E-136 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMALA_RS14595 9f1195b363db710cfee0ea3ca3cceab0 472 ProSitePatterns PS00571 Amidases signature. 155 186 - T 29-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 SMALA_RS14595 9f1195b363db710cfee0ea3ca3cceab0 472 Gene3D G3DSA:3.90.1300.10 1 469 9.3E-137 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMALA_RS35675 62bbd2e765821fb870b51ed499e791cf 354 SUPERFAMILY SSF50129 1 170 1.11E-45 T 29-03-2018 IPR011032 GroES-like SMALA_RS35675 62bbd2e765821fb870b51ed499e791cf 354 Pfam PF00107 Zinc-binding dehydrogenase 176 306 3.4E-25 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMALA_RS35675 62bbd2e765821fb870b51ed499e791cf 354 SMART SM00829 10 344 4.5E-7 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS35675 62bbd2e765821fb870b51ed499e791cf 354 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 128 1.2E-30 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS35675 62bbd2e765821fb870b51ed499e791cf 354 Gene3D G3DSA:3.40.50.10730 154 314 6.8E-36 T 29-03-2018 SMALA_RS35675 62bbd2e765821fb870b51ed499e791cf 354 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 SMALA_RS35675 62bbd2e765821fb870b51ed499e791cf 354 Gene3D G3DSA:3.90.180.10 1 153 1.2E-45 T 29-03-2018 SMALA_RS35675 62bbd2e765821fb870b51ed499e791cf 354 SUPERFAMILY SSF51735 138 314 9.36E-40 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS15820 ee10019201f586ebcb787bd334b6a49d 759 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 615 753 4.5E-32 T 29-03-2018 IPR002178 PTS EIIA type-2 domain SMALA_RS15820 ee10019201f586ebcb787bd334b6a49d 759 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 22 112 1.7E-17 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 SMALA_RS15820 ee10019201f586ebcb787bd334b6a49d 759 Pfam PF02378 Phosphotransferase system, EIIC 164 438 3.0E-20 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 SMALA_RS15820 ee10019201f586ebcb787bd334b6a49d 759 SUPERFAMILY SSF52794 19 115 4.88E-36 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 SMALA_RS15820 ee10019201f586ebcb787bd334b6a49d 759 SUPERFAMILY SSF55804 611 757 1.26E-34 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 SMALA_RS15820 ee10019201f586ebcb787bd334b6a49d 759 Gene3D G3DSA:3.40.930.10 610 758 4.9E-34 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 SMALA_RS15820 ee10019201f586ebcb787bd334b6a49d 759 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 156 489 7.8E-90 T 29-03-2018 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 SMALA_RS15820 ee10019201f586ebcb787bd334b6a49d 759 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 617 742 2.2E-33 T 29-03-2018 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 SMALA_RS15820 ee10019201f586ebcb787bd334b6a49d 759 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 22 103 6.8E-31 T 29-03-2018 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 KEGG: 00051+2.7.1.202|KEGG: 00230+2.7.1.20|MetaCyc: PWY-6619 SMALA_RS15820 ee10019201f586ebcb787bd334b6a49d 759 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 660 676 - T 29-03-2018 IPR002178 PTS EIIA type-2 domain SMALA_RS15820 ee10019201f586ebcb787bd334b6a49d 759 Gene3D G3DSA:3.40.50.2300 19 116 1.0E-37 T 29-03-2018 SMALA_RS28315 fe5300fdf2859aca851cc01a4edc22a1 429 SUPERFAMILY SSF50939 191 341 1.52E-11 T 29-03-2018 IPR011040 Sialidases KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 SMALA_RS28315 fe5300fdf2859aca851cc01a4edc22a1 429 Gene3D G3DSA:2.130.10.10 7 226 4.7E-4 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMALA_RS28315 fe5300fdf2859aca851cc01a4edc22a1 429 Gene3D G3DSA:2.120.10.10 227 428 3.4E-13 T 29-03-2018 SMALA_RS13635 1e771880f0271ef47f17b8989134bcf0 957 Gene3D G3DSA:1.25.40.10 687 902 5.1E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS13635 1e771880f0271ef47f17b8989134bcf0 957 Gene3D G3DSA:1.10.10.10 903 950 2.9E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS13635 1e771880f0271ef47f17b8989134bcf0 957 SMART SM00421 892 949 3.2E-18 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS13635 1e771880f0271ef47f17b8989134bcf0 957 Pfam PF13191 AAA ATPase domain 23 166 2.0E-12 T 29-03-2018 SMALA_RS13635 1e771880f0271ef47f17b8989134bcf0 957 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 909 925 1.2E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS13635 1e771880f0271ef47f17b8989134bcf0 957 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 895 909 1.2E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS13635 1e771880f0271ef47f17b8989134bcf0 957 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 925 937 1.2E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS13635 1e771880f0271ef47f17b8989134bcf0 957 SUPERFAMILY SSF48452 603 699 2.71E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS13635 1e771880f0271ef47f17b8989134bcf0 957 Pfam PF00196 Bacterial regulatory proteins, luxR family 894 945 7.7E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS13635 1e771880f0271ef47f17b8989134bcf0 957 ProSitePatterns PS00622 LuxR-type HTH domain signature. 909 936 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS13635 1e771880f0271ef47f17b8989134bcf0 957 SUPERFAMILY SSF48452 608 669 3.79E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS13635 1e771880f0271ef47f17b8989134bcf0 957 SUPERFAMILY SSF48452 714 858 3.79E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS13635 1e771880f0271ef47f17b8989134bcf0 957 Gene3D G3DSA:3.40.50.300 23 209 4.0E-4 T 29-03-2018 SMALA_RS13635 1e771880f0271ef47f17b8989134bcf0 957 Gene3D G3DSA:1.25.40.10 393 686 9.3E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS13635 1e771880f0271ef47f17b8989134bcf0 957 SUPERFAMILY SSF46894 887 945 1.22E-14 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS03185 219c7367e1b8e7b9e768fd92a133043c 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 6.7E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS03185 219c7367e1b8e7b9e768fd92a133043c 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 6.7E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS03185 219c7367e1b8e7b9e768fd92a133043c 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 6.7E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS03185 219c7367e1b8e7b9e768fd92a133043c 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 6.7E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS03185 219c7367e1b8e7b9e768fd92a133043c 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 6.7E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS03185 219c7367e1b8e7b9e768fd92a133043c 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 6.7E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS03185 219c7367e1b8e7b9e768fd92a133043c 250 Gene3D G3DSA:3.40.50.720 1 51 4.2E-12 T 29-03-2018 SMALA_RS03185 219c7367e1b8e7b9e768fd92a133043c 250 Gene3D G3DSA:3.40.50.720 52 249 1.6E-56 T 29-03-2018 SMALA_RS03185 219c7367e1b8e7b9e768fd92a133043c 250 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 247 9.5E-57 T 29-03-2018 SMALA_RS03185 219c7367e1b8e7b9e768fd92a133043c 250 SUPERFAMILY SSF51735 5 248 6.93E-74 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS03185 219c7367e1b8e7b9e768fd92a133043c 250 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 138 166 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMALA_RS03185 219c7367e1b8e7b9e768fd92a133043c 250 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 192 1.8E-5 T 29-03-2018 SMALA_RS24910 561116d500cbea7f6ef87f45401bbe17 280 Gene3D G3DSA:1.10.260.40 5 101 5.4E-14 T 29-03-2018 SMALA_RS24910 561116d500cbea7f6ef87f45401bbe17 280 Pfam PF13560 Helix-turn-helix domain 14 71 3.2E-12 T 29-03-2018 SMALA_RS24910 561116d500cbea7f6ef87f45401bbe17 280 SUPERFAMILY SSF47413 11 72 3.66E-11 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS24910 561116d500cbea7f6ef87f45401bbe17 280 SMART SM00530 18 73 1.4E-5 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS00505 e50c9424bb8e719827da9f3989d25dcb 707 SUPERFAMILY SSF48452 521 683 3.52E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS00505 e50c9424bb8e719827da9f3989d25dcb 707 Gene3D G3DSA:1.25.40.10 421 705 1.5E-14 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS00505 e50c9424bb8e719827da9f3989d25dcb 707 Gene3D G3DSA:3.40.50.300 90 250 1.1E-11 T 29-03-2018 SMALA_RS00505 e50c9424bb8e719827da9f3989d25dcb 707 SUPERFAMILY SSF52540 95 304 9.09E-14 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS32935 36f587afba1776082441171b13b74763 373 Pfam PF02355 Protein export membrane protein 111 304 7.0E-65 T 29-03-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial SMALA_RS32935 36f587afba1776082441171b13b74763 373 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 18 306 24.463 T 29-03-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 SMALA_RS32935 36f587afba1776082441171b13b74763 373 PRINTS PR01755 Bacterial translocase SecF protein signature 45 60 3.6E-22 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial SMALA_RS32935 36f587afba1776082441171b13b74763 373 PRINTS PR01755 Bacterial translocase SecF protein signature 238 253 3.6E-22 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial SMALA_RS32935 36f587afba1776082441171b13b74763 373 PRINTS PR01755 Bacterial translocase SecF protein signature 155 169 3.6E-22 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial SMALA_RS32935 36f587afba1776082441171b13b74763 373 PRINTS PR01755 Bacterial translocase SecF protein signature 203 221 3.6E-22 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial SMALA_RS32935 36f587afba1776082441171b13b74763 373 SUPERFAMILY SSF82866 126 305 2.09E-30 T 29-03-2018 SMALA_RS32935 36f587afba1776082441171b13b74763 373 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 84 292 7.6E-49 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial SMALA_RS32935 36f587afba1776082441171b13b74763 373 Gene3D G3DSA:1.20.1640.10 93 316 4.7E-25 T 29-03-2018 SMALA_RS32935 36f587afba1776082441171b13b74763 373 Pfam PF07549 SecD/SecF GG Motif 41 61 4.5E-5 T 29-03-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site SMALA_RS32935 36f587afba1776082441171b13b74763 373 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 46 295 3.7E-72 T 29-03-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 SMALA_RS18290 1f1b5245ce87eb8bad1c2ad1edb9d1f0 562 Gene3D G3DSA:2.60.40.230 194 292 0.0031 T 29-03-2018 SMALA_RS18290 1f1b5245ce87eb8bad1c2ad1edb9d1f0 562 Gene3D G3DSA:2.60.40.230 293 375 0.005 T 29-03-2018 SMALA_RS16580 39e5f970cd6303b85de275c2a35855bc 479 SUPERFAMILY SSF89796 37 177 7.98E-15 T 29-03-2018 IPR023606 CoA-transferase family III domain SMALA_RS16580 39e5f970cd6303b85de275c2a35855bc 479 Pfam PF02515 CoA-transferase family III 226 429 9.1E-52 T 29-03-2018 IPR003673 CoA-transferase family III GO:0003824 SMALA_RS16580 39e5f970cd6303b85de275c2a35855bc 479 Gene3D G3DSA:3.40.50.10540 220 440 1.3E-72 T 29-03-2018 IPR023606 CoA-transferase family III domain SMALA_RS16580 39e5f970cd6303b85de275c2a35855bc 479 Gene3D G3DSA:3.30.1540.10 100 178 2.4E-10 T 29-03-2018 SMALA_RS16580 39e5f970cd6303b85de275c2a35855bc 479 SUPERFAMILY SSF89796 224 428 1.31E-59 T 29-03-2018 IPR023606 CoA-transferase family III domain SMALA_RS08860 bc1aba56e27ed8d989d61861b6b6a054 263 SMART SM00382 29 222 1.4E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS08860 bc1aba56e27ed8d989d61861b6b6a054 263 SUPERFAMILY SSF52540 4 235 7.31E-49 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS08860 bc1aba56e27ed8d989d61861b6b6a054 263 Pfam PF00005 ABC transporter 21 171 4.6E-26 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS08860 bc1aba56e27ed8d989d61861b6b6a054 263 Gene3D G3DSA:3.40.50.300 1 240 1.2E-47 T 29-03-2018 SMALA_RS39415 e6e9614858e4e33eb936c5648f021e8e 368 Pfam PF13343 Bacterial extracellular solute-binding protein 150 334 4.3E-10 T 29-03-2018 SMALA_RS39415 e6e9614858e4e33eb936c5648f021e8e 368 Gene3D G3DSA:3.40.190.10 56 161 0.051 T 29-03-2018 SMALA_RS39415 e6e9614858e4e33eb936c5648f021e8e 368 Gene3D G3DSA:3.40.190.10 162 325 3.4E-14 T 29-03-2018 SMALA_RS39415 e6e9614858e4e33eb936c5648f021e8e 368 SUPERFAMILY SSF53850 70 357 9.78E-32 T 29-03-2018 SMALA_RS41165 6c81b58212f4f5d024bd9d987bf244ce 335 Pfam PF01032 FecCD transport family 16 330 1.9E-91 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 SMALA_RS41165 6c81b58212f4f5d024bd9d987bf244ce 335 Gene3D G3DSA:1.10.3470.10 1 334 1.6E-72 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SMALA_RS41165 6c81b58212f4f5d024bd9d987bf244ce 335 SUPERFAMILY SSF81345 4 331 2.35E-78 T 29-03-2018 IPR029022 ABC transporter, BtuC-like SMALA_RS22125 a7a2681cc8f09c9c5b247bc6f66d681f 269 ProSitePatterns PS01099 Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. 122 140 - T 29-03-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS22125 a7a2681cc8f09c9c5b247bc6f66d681f 269 SUPERFAMILY SSF52833 17 174 5.93E-50 T 29-03-2018 IPR012336 Thioredoxin-like fold SMALA_RS22125 a7a2681cc8f09c9c5b247bc6f66d681f 269 Gene3D G3DSA:3.40.30.10 83 176 4.7E-16 T 29-03-2018 SMALA_RS22125 a7a2681cc8f09c9c5b247bc6f66d681f 269 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 22 164 4.3E-51 T 29-03-2018 SMALA_RS22125 a7a2681cc8f09c9c5b247bc6f66d681f 269 TIGRFAM TIGR01958 nuoE_fam: NADH-quinone oxidoreductase, E subunit 22 164 2.4E-45 T 29-03-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS22125 a7a2681cc8f09c9c5b247bc6f66d681f 269 PIRSF PIRSF000216 3 224 1.1E-80 T 29-03-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS30000 4a53120b092521c58e44f1481b71e22b 467 Pfam PF05787 Bacterial protein of unknown function (DUF839) 50 456 8.3E-87 T 29-03-2018 IPR008557 Protein of unknown function DUF839 SMALA_RS30000 4a53120b092521c58e44f1481b71e22b 467 Gene3D G3DSA:2.130.10.120 175 462 1.0E-8 T 29-03-2018 SMALA_RS30000 4a53120b092521c58e44f1481b71e22b 467 SUPERFAMILY SSF63829 216 276 4.25E-10 T 29-03-2018 SMALA_RS30000 4a53120b092521c58e44f1481b71e22b 467 SUPERFAMILY SSF63829 333 458 4.25E-10 T 29-03-2018 SMALA_RS40120 dc4f2fbfebcb6d4a59cbc4fce17dd236 414 SUPERFAMILY SSF53850 42 406 1.8E-67 T 29-03-2018 SMALA_RS40120 dc4f2fbfebcb6d4a59cbc4fce17dd236 414 Pfam PF13416 Bacterial extracellular solute-binding protein 60 356 2.3E-36 T 29-03-2018 SMALA_RS40120 dc4f2fbfebcb6d4a59cbc4fce17dd236 414 Gene3D G3DSA:3.40.190.10 167 346 2.8E-32 T 29-03-2018 SMALA_RS40120 dc4f2fbfebcb6d4a59cbc4fce17dd236 414 Gene3D G3DSA:3.40.190.10 41 166 3.6E-18 T 29-03-2018 SMALA_RS37465 7591d9407da4571594747d74afeb59bf 280 Gene3D G3DSA:3.40.50.700 2 189 6.0E-33 T 29-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS37465 7591d9407da4571594747d74afeb59bf 280 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 17 162 4.7E-21 T 29-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS37465 7591d9407da4571594747d74afeb59bf 280 SUPERFAMILY SSF56770 5 228 6.93E-40 T 29-03-2018 SMALA_RS07725 73f01a0d8e2254e65164ac5c7a209c35 344 SUPERFAMILY SSF46689 98 200 9.68E-5 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS07725 73f01a0d8e2254e65164ac5c7a209c35 344 Gene3D G3DSA:1.10.10.60 90 140 0.0052 T 29-03-2018 SMALA_RS07725 73f01a0d8e2254e65164ac5c7a209c35 344 Pfam PF01610 Transposase 2 73 6.6E-8 T 29-03-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain SMALA_RS07725 73f01a0d8e2254e65164ac5c7a209c35 344 Pfam PF01610 Transposase 217 339 1.4E-12 T 29-03-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain SMALA_RS07725 73f01a0d8e2254e65164ac5c7a209c35 344 Gene3D G3DSA:1.10.10.10 160 210 4.8E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS26535 1b303a64e4382a6ee7955cd18be2d5fe 271 SMART SM00862 18 98 2.6E-7 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS26535 1b303a64e4382a6ee7955cd18be2d5fe 271 Pfam PF03704 Bacterial transcriptional activator domain 105 251 1.5E-37 T 29-03-2018 IPR005158 Bacterial transcriptional activator domain SMALA_RS26535 1b303a64e4382a6ee7955cd18be2d5fe 271 SUPERFAMILY SSF46894 2 76 1.64E-12 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS26535 1b303a64e4382a6ee7955cd18be2d5fe 271 Gene3D G3DSA:1.25.40.10 107 266 5.7E-21 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS26535 1b303a64e4382a6ee7955cd18be2d5fe 271 Pfam PF00486 Transcriptional regulatory protein, C terminal 24 96 7.8E-9 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS26535 1b303a64e4382a6ee7955cd18be2d5fe 271 SUPERFAMILY SSF48452 100 263 4.55E-31 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS26535 1b303a64e4382a6ee7955cd18be2d5fe 271 Gene3D G3DSA:1.10.10.10 12 106 8.0E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS26535 1b303a64e4382a6ee7955cd18be2d5fe 271 SMART SM01043 105 251 4.7E-43 T 29-03-2018 IPR005158 Bacterial transcriptional activator domain SMALA_RS40460 22cb758cf8c91ab60265724319ed1664 775 Gene3D G3DSA:3.40.50.740 122 334 7.7E-39 T 29-03-2018 SMALA_RS40460 22cb758cf8c91ab60265724319ed1664 775 Pfam PF01568 Molydopterin dinucleotide binding domain 648 755 3.1E-7 T 29-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 SMALA_RS40460 22cb758cf8c91ab60265724319ed1664 775 PIRSF PIRSF000144 6 766 0.0 T 29-03-2018 SMALA_RS40460 22cb758cf8c91ab60265724319ed1664 775 TIGRFAM TIGR01701 Fdhalpha-like: oxidoreductase alpha (molybdopterin) subunit 23 761 2.8E-275 T 29-03-2018 IPR010046 Oxidoreductase alpha (molybdopterin) subunit GO:0008863|GO:0030151|GO:0051539 SMALA_RS40460 22cb758cf8c91ab60265724319ed1664 775 Gene3D G3DSA:2.40.40.20 645 774 2.0E-22 T 29-03-2018 SMALA_RS40460 22cb758cf8c91ab60265724319ed1664 775 Pfam PF00384 Molybdopterin oxidoreductase 121 419 1.2E-25 T 29-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS40460 22cb758cf8c91ab60265724319ed1664 775 Gene3D G3DSA:3.40.50.740 335 623 2.5E-41 T 29-03-2018 SMALA_RS40460 22cb758cf8c91ab60265724319ed1664 775 SUPERFAMILY SSF53706 58 637 5.23E-136 T 29-03-2018 SMALA_RS40460 22cb758cf8c91ab60265724319ed1664 775 SUPERFAMILY SSF50692 644 765 1.7E-15 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain SMALA_RS35660 959711877b42fa8a36b65a467f1ff78e 313 Pfam PF03466 LysR substrate binding domain 89 292 7.5E-47 T 29-03-2018 IPR005119 LysR, substrate-binding SMALA_RS35660 959711877b42fa8a36b65a467f1ff78e 313 SUPERFAMILY SSF53850 90 294 1.09E-44 T 29-03-2018 SMALA_RS35660 959711877b42fa8a36b65a467f1ff78e 313 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 6.4E-20 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS35660 959711877b42fa8a36b65a467f1ff78e 313 Gene3D G3DSA:3.40.190.10 177 268 1.5E-26 T 29-03-2018 SMALA_RS35660 959711877b42fa8a36b65a467f1ff78e 313 SUPERFAMILY SSF46785 3 112 1.11E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS35660 959711877b42fa8a36b65a467f1ff78e 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 2.4E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS35660 959711877b42fa8a36b65a467f1ff78e 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 2.4E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS35660 959711877b42fa8a36b65a467f1ff78e 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 2.4E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS35660 959711877b42fa8a36b65a467f1ff78e 313 Gene3D G3DSA:3.40.190.10 90 176 1.5E-23 T 29-03-2018 SMALA_RS35660 959711877b42fa8a36b65a467f1ff78e 313 Gene3D G3DSA:1.10.10.10 1 85 5.7E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS11395 fb66ed0be427b884eb653457c09a157a 323 SMART SM00646 190 318 7.5E-16 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 SMALA_RS11395 fb66ed0be427b884eb653457c09a157a 323 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 107 318 1.3E-33 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 SMALA_RS11395 fb66ed0be427b884eb653457c09a157a 323 SUPERFAMILY SSF53187 104 322 2.54E-31 T 29-03-2018 SMALA_RS11395 fb66ed0be427b884eb653457c09a157a 323 Gene3D G3DSA:3.40.630.40 89 323 3.0E-42 T 29-03-2018 SMALA_RS04895 6e0e878f063db5e2795379ecedce44a9 290 PRINTS PR00412 Epoxide hydrolase signature 263 285 1.4E-10 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS04895 6e0e878f063db5e2795379ecedce44a9 290 PRINTS PR00412 Epoxide hydrolase signature 59 74 1.4E-10 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS04895 6e0e878f063db5e2795379ecedce44a9 290 PRINTS PR00412 Epoxide hydrolase signature 230 246 1.4E-10 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS04895 6e0e878f063db5e2795379ecedce44a9 290 PRINTS PR00412 Epoxide hydrolase signature 118 131 1.4E-10 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS04895 6e0e878f063db5e2795379ecedce44a9 290 Gene3D G3DSA:3.40.50.1820 9 290 4.7E-49 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS04895 6e0e878f063db5e2795379ecedce44a9 290 Pfam PF00561 alpha/beta hydrolase fold 32 274 2.2E-28 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS04895 6e0e878f063db5e2795379ecedce44a9 290 PRINTS PR00111 Alpha/beta hydrolase fold signature 104 117 1.4E-17 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS04895 6e0e878f063db5e2795379ecedce44a9 290 PRINTS PR00111 Alpha/beta hydrolase fold signature 59 74 1.4E-17 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS04895 6e0e878f063db5e2795379ecedce44a9 290 PRINTS PR00111 Alpha/beta hydrolase fold signature 118 131 1.4E-17 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS04895 6e0e878f063db5e2795379ecedce44a9 290 PRINTS PR00111 Alpha/beta hydrolase fold signature 232 246 1.4E-17 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS04895 6e0e878f063db5e2795379ecedce44a9 290 SUPERFAMILY SSF53474 5 287 2.7E-60 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS18600 9f3c58d0bbcb1fea334bca22dcd76532 463 Pfam PF06965 Na+/H+ antiporter 1 24 396 9.0E-134 T 29-03-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 SMALA_RS18600 9f3c58d0bbcb1fea334bca22dcd76532 463 TIGRFAM TIGR00773 NhaA: Na+/H+ antiporter NhaA 26 392 6.4E-100 T 29-03-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 SMALA_RS18600 9f3c58d0bbcb1fea334bca22dcd76532 463 Gene3D G3DSA:1.20.1530.10 20 402 3.1E-138 T 29-03-2018 IPR023171 Na/H antiporter domain SMALA_RS18600 9f3c58d0bbcb1fea334bca22dcd76532 463 Hamap MF_01844 Na(+)/H(+) antiporter NhaA [nhaA]. 21 402 20.691 T 29-03-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 SMALA_RS41995 8733af00a6ba205ab89aba60e5799290 388 Pfam PF00067 Cytochrome P450 197 358 6.1E-27 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS41995 8733af00a6ba205ab89aba60e5799290 388 PRINTS PR00385 P450 superfamily signature 261 272 4.4E-5 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS41995 8733af00a6ba205ab89aba60e5799290 388 PRINTS PR00385 P450 superfamily signature 337 348 4.4E-5 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS41995 8733af00a6ba205ab89aba60e5799290 388 PRINTS PR00385 P450 superfamily signature 226 243 4.4E-5 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS41995 8733af00a6ba205ab89aba60e5799290 388 PRINTS PR00385 P450 superfamily signature 328 337 4.4E-5 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS41995 8733af00a6ba205ab89aba60e5799290 388 SUPERFAMILY SSF48264 30 382 1.44E-82 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS41995 8733af00a6ba205ab89aba60e5799290 388 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 330 339 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMALA_RS41995 8733af00a6ba205ab89aba60e5799290 388 PRINTS PR00359 B-class P450 signature 279 306 3.6E-39 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS41995 8733af00a6ba205ab89aba60e5799290 388 PRINTS PR00359 B-class P450 signature 328 337 3.6E-39 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS41995 8733af00a6ba205ab89aba60e5799290 388 PRINTS PR00359 B-class P450 signature 80 91 3.6E-39 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS41995 8733af00a6ba205ab89aba60e5799290 388 PRINTS PR00359 B-class P450 signature 180 202 3.6E-39 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS41995 8733af00a6ba205ab89aba60e5799290 388 PRINTS PR00359 B-class P450 signature 261 272 3.6E-39 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS41995 8733af00a6ba205ab89aba60e5799290 388 PRINTS PR00359 B-class P450 signature 337 348 3.6E-39 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS41995 8733af00a6ba205ab89aba60e5799290 388 PRINTS PR00359 B-class P450 signature 127 143 3.6E-39 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS41995 8733af00a6ba205ab89aba60e5799290 388 PRINTS PR00359 B-class P450 signature 307 322 3.6E-39 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS41995 8733af00a6ba205ab89aba60e5799290 388 Gene3D G3DSA:1.10.630.10 23 384 2.5E-63 T 29-03-2018 SMALA_RS23655 443efd929419b7a8b50d8417d1c95ea2 260 Gene3D G3DSA:3.40.830.10 1 260 1.7E-80 T 29-03-2018 SMALA_RS23655 443efd929419b7a8b50d8417d1c95ea2 260 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 28 236 8.6E-45 T 29-03-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 SMALA_RS23655 443efd929419b7a8b50d8417d1c95ea2 260 PIRSF PIRSF006157 3 260 2.4E-87 T 29-03-2018 IPR014436 Extradiol aromatic ring-opening dioxygenase, DODA-type GO:0008270|GO:0016701|GO:0055114 SMALA_RS23655 443efd929419b7a8b50d8417d1c95ea2 260 SUPERFAMILY SSF53213 7 260 2.22E-85 T 29-03-2018 SMALA_RS38905 f3e8bbe77dd827c7a43735f1b7d8fc11 294 PRINTS PR00412 Epoxide hydrolase signature 113 126 1.5E-10 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS38905 f3e8bbe77dd827c7a43735f1b7d8fc11 294 PRINTS PR00412 Epoxide hydrolase signature 228 244 1.5E-10 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS38905 f3e8bbe77dd827c7a43735f1b7d8fc11 294 PRINTS PR00412 Epoxide hydrolase signature 260 282 1.5E-10 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS38905 f3e8bbe77dd827c7a43735f1b7d8fc11 294 PRINTS PR00412 Epoxide hydrolase signature 33 51 1.5E-10 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS38905 f3e8bbe77dd827c7a43735f1b7d8fc11 294 PRINTS PR00412 Epoxide hydrolase signature 99 112 1.5E-10 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS38905 f3e8bbe77dd827c7a43735f1b7d8fc11 294 PRINTS PR00111 Alpha/beta hydrolase fold signature 52 67 4.3E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS38905 f3e8bbe77dd827c7a43735f1b7d8fc11 294 PRINTS PR00111 Alpha/beta hydrolase fold signature 230 244 4.3E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS38905 f3e8bbe77dd827c7a43735f1b7d8fc11 294 Gene3D G3DSA:3.40.50.1820 3 287 3.4E-49 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS38905 f3e8bbe77dd827c7a43735f1b7d8fc11 294 Pfam PF00561 alpha/beta hydrolase fold 27 270 1.9E-24 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS38905 f3e8bbe77dd827c7a43735f1b7d8fc11 294 SUPERFAMILY SSF53474 3 282 4.2E-65 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS18665 04acf99a22a0fadba79f989f43928af8 455 Gene3D G3DSA:3.40.50.300 3 454 3.9E-115 T 29-03-2018 SMALA_RS18665 04acf99a22a0fadba79f989f43928af8 455 SUPERFAMILY SSF52540 231 296 1.13E-34 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS18665 04acf99a22a0fadba79f989f43928af8 455 SUPERFAMILY SSF52540 20 189 1.13E-34 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS18665 04acf99a22a0fadba79f989f43928af8 455 Pfam PF02374 Anion-transporting ATPase 20 291 1.3E-26 T 29-03-2018 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 SMALA_RS26445 8ed2c6a039d81e2d7a078135f8670904 187 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 61 9.9E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS26445 8ed2c6a039d81e2d7a078135f8670904 187 SUPERFAMILY SSF48498 81 183 3.51E-11 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS26445 8ed2c6a039d81e2d7a078135f8670904 187 SUPERFAMILY SSF46689 4 78 4.09E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS26445 8ed2c6a039d81e2d7a078135f8670904 187 Gene3D G3DSA:1.10.357.10 1 186 1.3E-33 T 29-03-2018 SMALA_RS27310 1cad7218b94894a7621f5c5c7b30865b 515 Gene3D G3DSA:3.90.1200.10 234 487 8.8E-13 T 29-03-2018 SMALA_RS27310 1cad7218b94894a7621f5c5c7b30865b 515 SUPERFAMILY SSF56112 194 495 1.53E-19 T 29-03-2018 IPR011009 Protein kinase-like domain SMALA_RS27310 1cad7218b94894a7621f5c5c7b30865b 515 Pfam PF01636 Phosphotransferase enzyme family 212 465 1.5E-8 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase SMALA_RS34180 6f6ef101c9649a81ecf7ecdc4132148e 163 SUPERFAMILY SSF88659 101 155 1.1E-10 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS34180 6f6ef101c9649a81ecf7ecdc4132148e 163 SUPERFAMILY SSF88946 3 72 2.59E-12 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS34180 6f6ef101c9649a81ecf7ecdc4132148e 163 Gene3D G3DSA:1.10.1740.10 1 72 2.6E-14 T 29-03-2018 SMALA_RS34180 6f6ef101c9649a81ecf7ecdc4132148e 163 Gene3D G3DSA:1.10.10.10 73 158 5.5E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS34180 6f6ef101c9649a81ecf7ecdc4132148e 163 Pfam PF08281 Sigma-70, region 4 101 151 3.4E-11 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS34180 6f6ef101c9649a81ecf7ecdc4132148e 163 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 8 155 2.0E-15 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS34180 6f6ef101c9649a81ecf7ecdc4132148e 163 Pfam PF04542 Sigma-70 region 2 12 76 2.2E-10 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS36330 33fbbd4b84471599daeabd6eecc0b0d3 465 TIGRFAM TIGR03356 BGL: beta-galactosidase 22 450 1.0E-186 T 29-03-2018 IPR017736 Glycoside hydrolase, family 1, beta-glucosidase GO:0008422|GO:0030245 KEGG: 00460+3.2.1.21|KEGG: 00500+3.2.1.21|KEGG: 00940+3.2.1.21|MetaCyc: PWY-3121|MetaCyc: PWY-5176|MetaCyc: PWY-6002|MetaCyc: PWY-6788|MetaCyc: PWY-7091|MetaCyc: PWY-7092 SMALA_RS36330 33fbbd4b84471599daeabd6eecc0b0d3 465 SUPERFAMILY SSF51445 21 457 8.4E-158 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS36330 33fbbd4b84471599daeabd6eecc0b0d3 465 PRINTS PR00131 Glycosyl hydrolase family 1 signature 428 440 3.5E-21 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SMALA_RS36330 33fbbd4b84471599daeabd6eecc0b0d3 465 PRINTS PR00131 Glycosyl hydrolase family 1 signature 362 370 3.5E-21 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SMALA_RS36330 33fbbd4b84471599daeabd6eecc0b0d3 465 PRINTS PR00131 Glycosyl hydrolase family 1 signature 383 394 3.5E-21 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SMALA_RS36330 33fbbd4b84471599daeabd6eecc0b0d3 465 PRINTS PR00131 Glycosyl hydrolase family 1 signature 404 421 3.5E-21 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SMALA_RS36330 33fbbd4b84471599daeabd6eecc0b0d3 465 PRINTS PR00131 Glycosyl hydrolase family 1 signature 299 313 3.5E-21 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SMALA_RS36330 33fbbd4b84471599daeabd6eecc0b0d3 465 Gene3D G3DSA:3.20.20.80 12 461 4.7E-163 T 29-03-2018 SMALA_RS36330 33fbbd4b84471599daeabd6eecc0b0d3 465 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 25 39 - T 29-03-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site SMALA_RS36330 33fbbd4b84471599daeabd6eecc0b0d3 465 Pfam PF00232 Glycosyl hydrolase family 1 20 457 4.3E-152 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SMALA_RS07960 3d367365063284934178f149f17b7cba 279 SMART SM00530 9 81 5.6E-9 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS07960 3d367365063284934178f149f17b7cba 279 Pfam PF13560 Helix-turn-helix domain 5 83 2.3E-17 T 29-03-2018 SMALA_RS07960 3d367365063284934178f149f17b7cba 279 SUPERFAMILY SSF47413 29 80 9.48E-11 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS07960 3d367365063284934178f149f17b7cba 279 Gene3D G3DSA:1.10.260.40 1 83 3.5E-18 T 29-03-2018 SMALA_RS39910 b597f3fc3ff8635b3c4621ee7cef253e 227 Gene3D G3DSA:3.40.225.10 2 227 1.8E-55 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal SMALA_RS39910 b597f3fc3ff8635b3c4621ee7cef253e 227 SMART SM01007 5 184 1.4E-41 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal SMALA_RS39910 b597f3fc3ff8635b3c4621ee7cef253e 227 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 6 184 1.1E-40 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal SMALA_RS39910 b597f3fc3ff8635b3c4621ee7cef253e 227 SUPERFAMILY SSF53639 3 213 4.12E-49 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal SMALA_RS18950 dab0c439c134dfddd056ec71e73f2933 259 Gene3D G3DSA:3.30.450.40 82 258 9.5E-31 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS18950 dab0c439c134dfddd056ec71e73f2933 259 Gene3D G3DSA:1.10.10.10 2 70 2.5E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS18950 dab0c439c134dfddd056ec71e73f2933 259 SMART SM00346 10 98 3.6E-6 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMALA_RS18950 dab0c439c134dfddd056ec71e73f2933 259 Pfam PF09339 IclR helix-turn-helix domain 12 61 2.8E-12 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMALA_RS18950 dab0c439c134dfddd056ec71e73f2933 259 SUPERFAMILY SSF46785 10 77 1.88E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS18950 dab0c439c134dfddd056ec71e73f2933 259 Pfam PF01614 Bacterial transcriptional regulator 127 229 6.5E-18 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal SMALA_RS18950 dab0c439c134dfddd056ec71e73f2933 259 SUPERFAMILY SSF55781 82 255 2.35E-28 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS09140 8db4ff1b4568d14a87bf4e8f35abb362 95 Gene3D G3DSA:1.10.10.60 29 77 0.0015 T 29-03-2018 SMALA_RS15885 6edc61bd7fe30d755b58d930303b1783 320 TIGRFAM TIGR01819 F420_cofD: 2-phospho-L-lactate transferase 3 311 1.5E-128 T 29-03-2018 IPR010115 2-phospho-L-lactate transferase GO:0000287|GO:0016780|GO:0051188 KEGG: 00680+2.7.8.28|MetaCyc: PWY-5198 SMALA_RS15885 6edc61bd7fe30d755b58d930303b1783 320 Gene3D G3DSA:3.40.50.10680 92 320 1.5E-51 T 29-03-2018 SMALA_RS15885 6edc61bd7fe30d755b58d930303b1783 320 Gene3D G3DSA:3.40.50.10680 3 80 1.6E-13 T 29-03-2018 SMALA_RS15885 6edc61bd7fe30d755b58d930303b1783 320 Hamap MF_01257 2-phospho-L-lactate transferase [cofD]. 1 320 137.336 T 29-03-2018 IPR010115 2-phospho-L-lactate transferase GO:0000287|GO:0016780|GO:0051188 KEGG: 00680+2.7.8.28|MetaCyc: PWY-5198 SMALA_RS15885 6edc61bd7fe30d755b58d930303b1783 320 SUPERFAMILY SSF142338 3 316 2.62E-85 T 29-03-2018 SMALA_RS15885 6edc61bd7fe30d755b58d930303b1783 320 Pfam PF01933 Uncharacterised protein family UPF0052 3 281 5.7E-61 T 29-03-2018 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 SMALA_RS23740 a57a4d9019b205a7b50553781f58c0a6 920 SUPERFAMILY SSF56235 298 710 3.34E-214 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SMALA_RS23740 a57a4d9019b205a7b50553781f58c0a6 920 SUPERFAMILY SSF56235 737 920 3.34E-214 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SMALA_RS23740 a57a4d9019b205a7b50553781f58c0a6 920 SUPERFAMILY SSF56235 59 254 3.34E-214 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SMALA_RS23740 a57a4d9019b205a7b50553781f58c0a6 920 Gene3D G3DSA:3.60.20.10 692 908 4.4E-30 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SMALA_RS23740 a57a4d9019b205a7b50553781f58c0a6 920 Gene3D G3DSA:1.10.439.10 34 204 7.6E-54 T 29-03-2018 IPR023343 Penicillin amidase type, domain1 GO:0016811 SMALA_RS23740 a57a4d9019b205a7b50553781f58c0a6 920 Pfam PF01804 Penicillin amidase 63 909 1.1E-246 T 29-03-2018 IPR002692 Penicillin/GL-7-ACA/AHL/aculeacin-A acylase GO:0016787|GO:0017000 SMALA_RS23740 a57a4d9019b205a7b50553781f58c0a6 920 PIRSF PIRSF001227 20 920 4.8E-269 T 29-03-2018 IPR014395 Penicillin/GL-7-ACA/AHL acylase GO:0016811 SMALA_RS23740 a57a4d9019b205a7b50553781f58c0a6 920 Gene3D G3DSA:3.60.20.10 310 691 2.7E-113 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SMALA_RS02860 7b50ed4743539db4e87cfa025465afba 311 SUPERFAMILY SSF56601 40 293 3.17E-59 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMALA_RS02860 7b50ed4743539db4e87cfa025465afba 311 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 157 170 1.9E-15 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 SMALA_RS02860 7b50ed4743539db4e87cfa025465afba 311 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 70 81 1.9E-15 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 SMALA_RS02860 7b50ed4743539db4e87cfa025465afba 311 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 124 141 1.9E-15 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 SMALA_RS02860 7b50ed4743539db4e87cfa025465afba 311 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 35 278 1.2E-46 T 29-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 SMALA_RS02860 7b50ed4743539db4e87cfa025465afba 311 Gene3D G3DSA:3.40.710.10 9 310 6.6E-51 T 29-03-2018 SMALA_RS03130 767407fba3bc993793efd70f3a227414 467 Gene3D G3DSA:1.20.1250.20 13 213 4.1E-36 T 29-03-2018 SMALA_RS03130 767407fba3bc993793efd70f3a227414 467 Gene3D G3DSA:1.20.1250.20 240 451 3.8E-29 T 29-03-2018 SMALA_RS03130 767407fba3bc993793efd70f3a227414 467 ProSitePatterns PS00217 Sugar transport proteins signature 2. 117 142 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMALA_RS03130 767407fba3bc993793efd70f3a227414 467 Pfam PF00083 Sugar (and other) transporter 30 446 3.5E-48 T 29-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 SMALA_RS03130 767407fba3bc993793efd70f3a227414 467 SUPERFAMILY SSF103473 10 447 3.01E-83 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS23950 9f47e908978de31593e24a56a330dee6 361 Gene3D G3DSA:1.10.530.10 268 361 2.8E-25 T 29-03-2018 SMALA_RS23950 9f47e908978de31593e24a56a330dee6 361 Pfam PF03990 Domain of unknown function (DUF348) 85 122 2.5E-8 T 29-03-2018 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 SMALA_RS23950 9f47e908978de31593e24a56a330dee6 361 Pfam PF03990 Domain of unknown function (DUF348) 28 67 9.6E-11 T 29-03-2018 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 SMALA_RS23950 9f47e908978de31593e24a56a330dee6 361 Pfam PF03990 Domain of unknown function (DUF348) 142 182 5.1E-11 T 29-03-2018 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 SMALA_RS23950 9f47e908978de31593e24a56a330dee6 361 SUPERFAMILY SSF53955 282 358 2.97E-23 T 29-03-2018 IPR023346 Lysozyme-like domain SMALA_RS23950 9f47e908978de31593e24a56a330dee6 361 Pfam PF07501 G5 domain 200 272 8.8E-18 T 29-03-2018 IPR011098 G5 domain SMALA_RS23950 9f47e908978de31593e24a56a330dee6 361 Gene3D G3DSA:2.20.230.10 194 267 7.7E-19 T 29-03-2018 SMALA_RS23950 9f47e908978de31593e24a56a330dee6 361 Pfam PF06737 Transglycosylase-like domain 283 355 1.5E-21 T 29-03-2018 IPR010618 Transglycosylase-like SMALA_RS23950 9f47e908978de31593e24a56a330dee6 361 SMART SM01208 195 273 5.4E-21 T 29-03-2018 IPR011098 G5 domain SMALA_RS36015 66f446acd334366008ce2a65711aec76 205 Gene3D G3DSA:1.10.10.10 126 205 2.5E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS36015 66f446acd334366008ce2a65711aec76 205 SMART SM00421 141 198 1.8E-24 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS36015 66f446acd334366008ce2a65711aec76 205 Gene3D G3DSA:3.40.50.2300 1 125 4.3E-40 T 29-03-2018 SMALA_RS36015 66f446acd334366008ce2a65711aec76 205 SUPERFAMILY SSF46894 138 204 1.05E-19 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS36015 66f446acd334366008ce2a65711aec76 205 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 174 186 1.3E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS36015 66f446acd334366008ce2a65711aec76 205 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 174 1.3E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS36015 66f446acd334366008ce2a65711aec76 205 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 144 158 1.3E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS36015 66f446acd334366008ce2a65711aec76 205 SUPERFAMILY SSF52172 1 132 3.56E-36 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS36015 66f446acd334366008ce2a65711aec76 205 SMART SM00448 1 114 8.4E-35 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS36015 66f446acd334366008ce2a65711aec76 205 Pfam PF00072 Response regulator receiver domain 3 114 1.7E-29 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS36015 66f446acd334366008ce2a65711aec76 205 Pfam PF00196 Bacterial regulatory proteins, luxR family 143 197 1.9E-18 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS15510 8fb40ae3d727e51faa281d0763bc91c3 403 Gene3D G3DSA:2.30.42.10 87 204 2.2E-18 T 29-03-2018 SMALA_RS15510 8fb40ae3d727e51faa281d0763bc91c3 403 SMART SM00245 191 381 7.3E-43 T 29-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 SMALA_RS15510 8fb40ae3d727e51faa281d0763bc91c3 403 SMART SM00228 113 191 1.5E-14 T 29-03-2018 IPR001478 PDZ domain GO:0005515 SMALA_RS15510 8fb40ae3d727e51faa281d0763bc91c3 403 Pfam PF03572 Peptidase family S41 226 380 3.7E-39 T 29-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 SMALA_RS15510 8fb40ae3d727e51faa281d0763bc91c3 403 SUPERFAMILY SSF52096 80 134 1.24E-44 T 29-03-2018 IPR029045 ClpP/crotonase-like domain SMALA_RS15510 8fb40ae3d727e51faa281d0763bc91c3 403 SUPERFAMILY SSF52096 216 384 1.24E-44 T 29-03-2018 IPR029045 ClpP/crotonase-like domain SMALA_RS15510 8fb40ae3d727e51faa281d0763bc91c3 403 Gene3D G3DSA:3.90.226.10 205 396 3.4E-45 T 29-03-2018 SMALA_RS15510 8fb40ae3d727e51faa281d0763bc91c3 403 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 113 175 1.5E-9 T 29-03-2018 IPR001478 PDZ domain GO:0005515 SMALA_RS15510 8fb40ae3d727e51faa281d0763bc91c3 403 SUPERFAMILY SSF50156 101 209 1.6E-17 T 29-03-2018 IPR001478 PDZ domain GO:0005515 SMALA_RS11125 5714cde9c611faecaee2374229bfe9c8 419 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 60 407 2.0E-98 T 29-03-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 SMALA_RS11125 5714cde9c611faecaee2374229bfe9c8 419 SUPERFAMILY SSF54909 55 411 4.83E-90 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel SMALA_RS11125 5714cde9c611faecaee2374229bfe9c8 419 Pfam PF04261 Dyp-type peroxidase family 60 407 7.5E-114 T 29-03-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 SMALA_RS11125 5714cde9c611faecaee2374229bfe9c8 419 TIGRFAM TIGR01412 tat_substr_1: Tat-translocated enzyme 6 418 2.9E-168 T 29-03-2018 IPR006313 Deferrochelatase/peroxidase EfeB GO:0004601|GO:0015684|GO:0020037|GO:0033212 SMALA_RS17135 c23b90860a7cdd1b936f5ed98e145b81 252 SMART SM00382 25 221 2.4E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS17135 c23b90860a7cdd1b936f5ed98e145b81 252 Gene3D G3DSA:3.40.50.300 1 245 3.1E-60 T 29-03-2018 SMALA_RS17135 c23b90860a7cdd1b936f5ed98e145b81 252 SUPERFAMILY SSF52540 2 221 2.97E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS17135 c23b90860a7cdd1b936f5ed98e145b81 252 Pfam PF00005 ABC transporter 18 159 1.4E-26 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS28400 b2b51649f19b4559367b0cb0c5667451 233 Gene3D G3DSA:2.60.120.180 23 232 6.9E-57 T 29-03-2018 IPR013319 Glycoside hydrolase family 11/12 GO:0004553 MetaCyc: PWY-6784 SMALA_RS28400 b2b51649f19b4559367b0cb0c5667451 233 SUPERFAMILY SSF49899 32 231 4.75E-51 T 29-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain SMALA_RS28400 b2b51649f19b4559367b0cb0c5667451 233 Pfam PF01670 Glycosyl hydrolase family 12 45 227 4.0E-20 T 29-03-2018 IPR002594 Glycoside hydrolase family 12 GO:0000272|GO:0008810 SMALA_RS29800 ffbe340907c368b7e47a70163e7cfb28 652 Gene3D G3DSA:3.40.50.920 487 626 3.6E-31 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMALA_RS29800 ffbe340907c368b7e47a70163e7cfb28 652 SUPERFAMILY SSF52518 292 476 4.55E-51 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold SMALA_RS29800 ffbe340907c368b7e47a70163e7cfb28 652 Pfam PF02779 Transketolase, pyrimidine binding domain 314 476 5.9E-37 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain SMALA_RS29800 ffbe340907c368b7e47a70163e7cfb28 652 ProSitePatterns PS00801 Transketolase signature 1. 28 47 - T 29-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SMALA_RS29800 ffbe340907c368b7e47a70163e7cfb28 652 SMART SM00861 314 478 1.2E-50 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain SMALA_RS29800 ffbe340907c368b7e47a70163e7cfb28 652 ProSitePatterns PS00802 Transketolase signature 2. 420 436 - T 29-03-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SMALA_RS29800 ffbe340907c368b7e47a70163e7cfb28 652 SUPERFAMILY SSF52518 3 344 3.46E-72 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold SMALA_RS29800 ffbe340907c368b7e47a70163e7cfb28 652 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 2 623 41.705 T 29-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SMALA_RS29800 ffbe340907c368b7e47a70163e7cfb28 652 Gene3D G3DSA:3.40.50.970 311 480 1.7E-38 T 29-03-2018 SMALA_RS29800 ffbe340907c368b7e47a70163e7cfb28 652 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 3 278 6.3E-107 T 29-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SMALA_RS29800 ffbe340907c368b7e47a70163e7cfb28 652 Gene3D G3DSA:3.40.50.970 1 310 3.0E-79 T 29-03-2018 SMALA_RS29800 ffbe340907c368b7e47a70163e7cfb28 652 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 4 619 4.5E-187 T 29-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SMALA_RS29800 ffbe340907c368b7e47a70163e7cfb28 652 SUPERFAMILY SSF52922 502 622 1.83E-26 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMALA_RS29800 ffbe340907c368b7e47a70163e7cfb28 652 Pfam PF02780 Transketolase, C-terminal domain 502 614 3.1E-28 T 29-03-2018 IPR033248 Transketolase, C-terminal domain SMALA_RS13640 03de59fa0366733c4c71bc2ef233bd34 552 PRINTS PR00757 Flavin-containing amine oxidase signature 240 262 4.9E-5 T 29-03-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 SMALA_RS13640 03de59fa0366733c4c71bc2ef233bd34 552 PRINTS PR00757 Flavin-containing amine oxidase signature 41 60 4.9E-5 T 29-03-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 SMALA_RS13640 03de59fa0366733c4c71bc2ef233bd34 552 Gene3D G3DSA:3.90.660.10 66 442 6.6E-47 T 29-03-2018 SMALA_RS13640 03de59fa0366733c4c71bc2ef233bd34 552 Gene3D G3DSA:3.50.50.60 443 551 1.7E-17 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS13640 03de59fa0366733c4c71bc2ef233bd34 552 Pfam PF01593 Flavin containing amine oxidoreductase 49 522 5.5E-46 T 29-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 SMALA_RS13640 03de59fa0366733c4c71bc2ef233bd34 552 SUPERFAMILY SSF54373 350 465 5.1E-24 T 29-03-2018 SMALA_RS13640 03de59fa0366733c4c71bc2ef233bd34 552 SUPERFAMILY SSF51905 487 528 1.85E-45 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS13640 03de59fa0366733c4c71bc2ef233bd34 552 SUPERFAMILY SSF51905 37 371 1.85E-45 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS35200 424b08ba1761981ef864dfd6f3ca21d0 333 Gene3D G3DSA:3.40.109.10 111 330 2.8E-24 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMALA_RS35200 424b08ba1761981ef864dfd6f3ca21d0 333 SUPERFAMILY SSF55469 118 175 6.28E-7 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMALA_RS35200 424b08ba1761981ef864dfd6f3ca21d0 333 SUPERFAMILY SSF55469 239 320 6.28E-7 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMALA_RS35200 424b08ba1761981ef864dfd6f3ca21d0 333 SUPERFAMILY SSF55469 4 88 5.71E-9 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMALA_RS35200 424b08ba1761981ef864dfd6f3ca21d0 333 Gene3D G3DSA:3.40.109.30 1 85 9.6E-11 T 29-03-2018 SMALA_RS19605 bf6695956fb02ddfc6d6dd3462b1b15f 494 PIRSF PIRSF010361 12 470 2.3E-146 T 29-03-2018 IPR016570 Uncharacterised conserved protein UCP010361, membrane SMALA_RS19605 bf6695956fb02ddfc6d6dd3462b1b15f 494 Pfam PF09594 Glycosyltransferase family 87 121 365 8.4E-14 T 29-03-2018 IPR018584 Glycosyltransferase family 87 GO:0016758 SMALA_RS41015 439f65f73ee13a112d29da3c86d0252d 189 SUPERFAMILY SSF55961 78 94 3.78E-7 T 29-03-2018 SMALA_RS41015 439f65f73ee13a112d29da3c86d0252d 189 SUPERFAMILY SSF55961 127 185 3.78E-7 T 29-03-2018 SMALA_RS41015 439f65f73ee13a112d29da3c86d0252d 189 SUPERFAMILY SSF55961 17 45 3.78E-7 T 29-03-2018 SMALA_RS41015 439f65f73ee13a112d29da3c86d0252d 189 Gene3D G3DSA:3.30.530.20 13 187 1.7E-16 T 29-03-2018 IPR023393 START-like domain SMALA_RS27530 e7d98e2229e0d8c4777b8b4dc3a16409 232 Pfam PF13671 AAA domain 59 182 2.9E-7 T 29-03-2018 SMALA_RS27530 e7d98e2229e0d8c4777b8b4dc3a16409 232 Gene3D G3DSA:3.40.50.300 55 222 3.6E-11 T 29-03-2018 SMALA_RS27530 e7d98e2229e0d8c4777b8b4dc3a16409 232 SUPERFAMILY SSF52540 54 185 2.54E-11 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS15970 822788141e597eae212fb357fb8f88c7 382 SUPERFAMILY SSF51246 308 377 2.98E-16 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 SMALA_RS15970 822788141e597eae212fb357fb8f88c7 382 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 5 362 39.968 T 29-03-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 SMALA_RS15970 822788141e597eae212fb357fb8f88c7 382 Gene3D G3DSA:3.30.1490.20 117 182 3.2E-18 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SMALA_RS15970 822788141e597eae212fb357fb8f88c7 382 Pfam PF02222 ATP-grasp domain 112 283 5.1E-49 T 29-03-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type SMALA_RS15970 822788141e597eae212fb357fb8f88c7 382 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 6 367 3.0E-115 T 29-03-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 SMALA_RS15970 822788141e597eae212fb357fb8f88c7 382 SUPERFAMILY SSF56059 102 303 6.54E-61 T 29-03-2018 SMALA_RS15970 822788141e597eae212fb357fb8f88c7 382 Gene3D G3DSA:3.40.50.20 3 90 5.0E-23 T 29-03-2018 SMALA_RS15970 822788141e597eae212fb357fb8f88c7 382 Gene3D G3DSA:3.30.470.20 183 378 1.4E-45 T 29-03-2018 SMALA_RS15970 822788141e597eae212fb357fb8f88c7 382 SUPERFAMILY SSF52440 4 97 2.59E-24 T 29-03-2018 IPR016185 Pre-ATP-grasp domain SMALA_RS02075 6d3a5730661ec3d15e5f53b9afe9c65f 311 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 105 283 8.3E-19 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 SMALA_RS02075 6d3a5730661ec3d15e5f53b9afe9c65f 311 SUPERFAMILY SSF56529 74 283 4.32E-29 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 SMALA_RS02075 6d3a5730661ec3d15e5f53b9afe9c65f 311 Gene3D G3DSA:3.90.850.10 32 291 5.2E-37 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 SMALA_RS37890 9e8ce0167de85284d0b1f28ead0e3d4c 474 Pfam PF12275 Protein of unknown function (DUF3616) 289 404 0.0044 T 29-03-2018 IPR022060 Protein of unknown function DUF3616 SMALA_RS10365 19286871515d7463622e6cdf18c346b5 269 Gene3D G3DSA:1.20.120.450 7 150 2.5E-17 T 29-03-2018 SMALA_RS10365 19286871515d7463622e6cdf18c346b5 269 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 25 242 2.9E-24 T 29-03-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type SMALA_RS10365 19286871515d7463622e6cdf18c346b5 269 SUPERFAMILY SSF109854 22 149 2.2E-10 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes SMALA_RS10365 19286871515d7463622e6cdf18c346b5 269 Pfam PF07398 MDMPI C-terminal domain 156 260 8.0E-13 T 29-03-2018 IPR010872 MDMPI C-terminal SMALA_RS10365 19286871515d7463622e6cdf18c346b5 269 Gene3D G3DSA:3.30.1050.10 158 259 0.0076 T 29-03-2018 IPR003033 SCP2 sterol-binding domain SMALA_RS10365 19286871515d7463622e6cdf18c346b5 269 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 12 143 4.5E-19 T 29-03-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 SMALA_RS24700 3254fedae55beb1427837fd688165b81 538 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 296 308 3.7E-21 T 29-03-2018 SMALA_RS24700 3254fedae55beb1427837fd688165b81 538 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 198 214 3.7E-21 T 29-03-2018 SMALA_RS24700 3254fedae55beb1427837fd688165b81 538 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 330 354 3.7E-21 T 29-03-2018 SMALA_RS24700 3254fedae55beb1427837fd688165b81 538 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 222 236 3.7E-21 T 29-03-2018 SMALA_RS24700 3254fedae55beb1427837fd688165b81 538 Pfam PF02384 N-6 DNA Methylase 174 498 7.4E-111 T 29-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 SMALA_RS24700 3254fedae55beb1427837fd688165b81 538 Gene3D G3DSA:3.40.50.150 196 493 1.2E-61 T 29-03-2018 SMALA_RS24700 3254fedae55beb1427837fd688165b81 538 SUPERFAMILY SSF53335 13 51 7.25E-130 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS24700 3254fedae55beb1427837fd688165b81 538 SUPERFAMILY SSF53335 86 537 7.25E-130 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS24700 3254fedae55beb1427837fd688165b81 538 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 299 305 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 SMALA_RS24700 3254fedae55beb1427837fd688165b81 538 Pfam PF12161 HsdM N-terminal domain 15 155 5.0E-22 T 29-03-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain SMALA_RS41465 fa210ef95fce555f68723bd5a1e2e81c 773 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 436 557 7.4E-11 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS41465 fa210ef95fce555f68723bd5a1e2e81c 773 SMART SM00825 Beta-ketoacyl synthase 69 477 1.8E-125 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS41465 fa210ef95fce555f68723bd5a1e2e81c 773 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 311 426 3.1E-32 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS41465 fa210ef95fce555f68723bd5a1e2e81c 773 Gene3D G3DSA:3.40.47.10 59 315 4.4E-64 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS41465 fa210ef95fce555f68723bd5a1e2e81c 773 SMART SM00823 Phosphopantetheine attachment site 655 723 6.3E-14 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS41465 fa210ef95fce555f68723bd5a1e2e81c 773 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 67 303 1.4E-61 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS41465 fa210ef95fce555f68723bd5a1e2e81c 773 Gene3D G3DSA:1.10.1200.10 637 730 3.6E-13 T 29-03-2018 SMALA_RS41465 fa210ef95fce555f68723bd5a1e2e81c 773 SUPERFAMILY SSF53901 63 425 2.8E-72 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS41465 fa210ef95fce555f68723bd5a1e2e81c 773 Gene3D G3DSA:3.40.47.10 318 475 7.6E-44 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS41465 fa210ef95fce555f68723bd5a1e2e81c 773 Pfam PF00550 Phosphopantetheine attachment site 657 719 7.4E-8 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS41465 fa210ef95fce555f68723bd5a1e2e81c 773 SUPERFAMILY SSF47336 651 728 3.66E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS32480 3bd52464f4a80d0b59115673fbf11432 246 Gene3D G3DSA:3.10.520.10 4 241 6.2E-62 T 29-03-2018 SMALA_RS32480 3bd52464f4a80d0b59115673fbf11432 246 SUPERFAMILY SSF143631 1 240 7.19E-58 T 29-03-2018 IPR003374 ApbE-like domain SMALA_RS32480 3bd52464f4a80d0b59115673fbf11432 246 Pfam PF02424 ApbE family 1 84 4.4E-7 T 29-03-2018 IPR024932 Flavin transferase ApbE GO:0017013 SMALA_RS32480 3bd52464f4a80d0b59115673fbf11432 246 Pfam PF02424 ApbE family 88 222 1.4E-36 T 29-03-2018 IPR024932 Flavin transferase ApbE GO:0017013 SMALA_RS41825 ab9b22ac852485e168d96a5bffdbfdaa 325 SUPERFAMILY SSF51735 122 290 1.06E-35 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS41825 ab9b22ac852485e168d96a5bffdbfdaa 325 SUPERFAMILY SSF50129 1 148 1.27E-27 T 29-03-2018 IPR011032 GroES-like SMALA_RS41825 ab9b22ac852485e168d96a5bffdbfdaa 325 Pfam PF13602 Zinc-binding dehydrogenase 193 322 7.5E-24 T 29-03-2018 SMALA_RS41825 ab9b22ac852485e168d96a5bffdbfdaa 325 SMART SM00829 10 322 6.2E-14 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS41825 ab9b22ac852485e168d96a5bffdbfdaa 325 Gene3D G3DSA:3.90.180.10 1 325 9.4E-57 T 29-03-2018 SMALA_RS28740 034e5672aba7477e6c3b5576383e342f 276 Pfam PF13464 Domain of unknown function (DUF4115) 195 267 3.7E-16 T 29-03-2018 IPR025194 Domain of unknown function DUF4115 SMALA_RS28740 034e5672aba7477e6c3b5576383e342f 276 Gene3D G3DSA:1.10.260.40 10 97 3.2E-7 T 29-03-2018 SMALA_RS28740 034e5672aba7477e6c3b5576383e342f 276 Pfam PF13413 Helix-turn-helix domain 24 84 4.3E-19 T 29-03-2018 SMALA_RS32960 f01076db669186386aacc57f5d6eb327 238 SMART SM00849 12 202 3.8E-37 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS32960 f01076db669186386aacc57f5d6eb327 238 SUPERFAMILY SSF56281 6 222 2.62E-48 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS32960 f01076db669186386aacc57f5d6eb327 238 Pfam PF00753 Metallo-beta-lactamase superfamily 11 202 3.6E-27 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS32960 f01076db669186386aacc57f5d6eb327 238 Gene3D G3DSA:3.60.15.10 1 224 1.2E-42 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS01395 feb5bb2afccea4464d8a775865dbfd9e 894 SMART SM00860 521 649 3.1E-7 T 29-03-2018 IPR018958 Knr4/Smi1-like domain SMALA_RS01395 feb5bb2afccea4464d8a775865dbfd9e 894 SUPERFAMILY SSF160631 513 647 4.97E-11 T 29-03-2018 SMALA_RS01395 feb5bb2afccea4464d8a775865dbfd9e 894 Gene3D G3DSA:1.25.40.10 663 817 0.25 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS01395 feb5bb2afccea4464d8a775865dbfd9e 894 SUPERFAMILY SSF49785 321 425 1.11E-5 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS01395 feb5bb2afccea4464d8a775865dbfd9e 894 Gene3D G3DSA:3.40.1580.10 501 652 8.4E-15 T 29-03-2018 SMALA_RS01395 feb5bb2afccea4464d8a775865dbfd9e 894 Gene3D G3DSA:2.60.120.260 308 447 5.4E-16 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS26130 27c53b7d52940b60a3a466beba70c9ba 137 Gene3D G3DSA:1.10.10.10 1 83 9.4E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS26130 27c53b7d52940b60a3a466beba70c9ba 137 Pfam PF01475 Ferric uptake regulator family 11 104 9.2E-25 T 29-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 SMALA_RS26130 27c53b7d52940b60a3a466beba70c9ba 137 SUPERFAMILY SSF46785 3 134 4.21E-33 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS35400 42bda59ad975be8782d030f203769fc3 236 Gene3D G3DSA:1.20.120.530 77 235 4.3E-31 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS35400 42bda59ad975be8782d030f203769fc3 236 Pfam PF07729 FCD domain 99 220 3.6E-27 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS35400 42bda59ad975be8782d030f203769fc3 236 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 75 3.4E-18 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS35400 42bda59ad975be8782d030f203769fc3 236 Gene3D G3DSA:1.10.10.10 4 76 9.3E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS35400 42bda59ad975be8782d030f203769fc3 236 SMART SM00345 18 77 4.2E-16 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS35400 42bda59ad975be8782d030f203769fc3 236 SUPERFAMILY SSF48008 97 224 1.8E-29 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS35400 42bda59ad975be8782d030f203769fc3 236 SUPERFAMILY SSF46785 7 93 5.87E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS35400 42bda59ad975be8782d030f203769fc3 236 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 51 67 2.5E-10 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS35400 42bda59ad975be8782d030f203769fc3 236 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 37 51 2.5E-10 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS35400 42bda59ad975be8782d030f203769fc3 236 SMART SM00895 99 221 8.7E-21 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS41315 aa8d5bdad6fe593729c3dbdc2a9c97df 332 Pfam PF13407 Periplasmic binding protein domain 53 306 9.8E-26 T 29-03-2018 IPR025997 Periplasmic binding protein SMALA_RS41315 aa8d5bdad6fe593729c3dbdc2a9c97df 332 Gene3D G3DSA:3.40.50.2300 50 164 1.9E-8 T 29-03-2018 SMALA_RS41315 aa8d5bdad6fe593729c3dbdc2a9c97df 332 SUPERFAMILY SSF53822 50 323 3.19E-34 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SMALA_RS41315 aa8d5bdad6fe593729c3dbdc2a9c97df 332 Gene3D G3DSA:3.40.50.2300 165 317 1.6E-15 T 29-03-2018 SMALA_RS28860 64e7c8e963d61d615a8a66b21df984da 236 SMART SM00448 1 114 1.9E-38 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS28860 64e7c8e963d61d615a8a66b21df984da 236 SMART SM00862 159 231 2.0E-25 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS28860 64e7c8e963d61d615a8a66b21df984da 236 Pfam PF00072 Response regulator receiver domain 4 114 7.8E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS28860 64e7c8e963d61d615a8a66b21df984da 236 Gene3D G3DSA:3.40.50.2300 1 131 1.2E-35 T 29-03-2018 SMALA_RS28860 64e7c8e963d61d615a8a66b21df984da 236 Gene3D G3DSA:1.10.10.10 132 236 5.1E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS28860 64e7c8e963d61d615a8a66b21df984da 236 Pfam PF00486 Transcriptional regulatory protein, C terminal 159 231 2.7E-25 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS28860 64e7c8e963d61d615a8a66b21df984da 236 SUPERFAMILY SSF52172 2 193 1.34E-37 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS24100 36d69c497754f2082cb56bf175f67cb3 530 Pfam PF07690 Major Facilitator Superfamily 37 431 1.5E-47 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS24100 36d69c497754f2082cb56bf175f67cb3 530 SUPERFAMILY SSF103473 488 519 1.83E-71 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS24100 36d69c497754f2082cb56bf175f67cb3 530 SUPERFAMILY SSF103473 28 221 1.83E-71 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS24100 36d69c497754f2082cb56bf175f67cb3 530 SUPERFAMILY SSF103473 270 440 1.83E-71 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS24100 36d69c497754f2082cb56bf175f67cb3 530 PRINTS PR01036 Tetracycline resistance protein TetB signature 95 117 2.8E-5 T 29-03-2018 SMALA_RS24100 36d69c497754f2082cb56bf175f67cb3 530 PRINTS PR01036 Tetracycline resistance protein TetB signature 379 399 2.8E-5 T 29-03-2018 SMALA_RS24100 36d69c497754f2082cb56bf175f67cb3 530 PRINTS PR01036 Tetracycline resistance protein TetB signature 421 440 2.8E-5 T 29-03-2018 SMALA_RS24100 36d69c497754f2082cb56bf175f67cb3 530 PRINTS PR01036 Tetracycline resistance protein TetB signature 156 180 2.8E-5 T 29-03-2018 SMALA_RS24100 36d69c497754f2082cb56bf175f67cb3 530 Gene3D G3DSA:1.20.1250.20 273 529 1.9E-25 T 29-03-2018 SMALA_RS24100 36d69c497754f2082cb56bf175f67cb3 530 Gene3D G3DSA:1.20.1250.20 29 220 3.7E-36 T 29-03-2018 SMALA_RS33290 967d044d971455eddfd3575371978264 369 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 149 358 2.1E-58 T 29-03-2018 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 SMALA_RS33290 967d044d971455eddfd3575371978264 369 Gene3D G3DSA:3.40.140.10 1 127 2.6E-28 T 29-03-2018 SMALA_RS33290 967d044d971455eddfd3575371978264 369 SUPERFAMILY SSF53927 8 148 1.16E-41 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 SMALA_RS33290 967d044d971455eddfd3575371978264 369 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 10 354 2.3E-115 T 29-03-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 SMALA_RS33290 967d044d971455eddfd3575371978264 369 Gene3D G3DSA:3.40.430.10 128 358 1.4E-70 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 SMALA_RS33290 967d044d971455eddfd3575371978264 369 Pfam PF01872 RibD C-terminal domain 150 353 3.8E-51 T 29-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 SMALA_RS33290 967d044d971455eddfd3575371978264 369 PIRSF PIRSF006769 2 361 2.2E-125 T 29-03-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 SMALA_RS33290 967d044d971455eddfd3575371978264 369 SUPERFAMILY SSF53597 148 356 1.8E-57 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 SMALA_RS33290 967d044d971455eddfd3575371978264 369 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 8 103 3.6E-17 T 29-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain SMALA_RS33290 967d044d971455eddfd3575371978264 369 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 54 92 - T 29-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 SMALA_RS11325 d51b62c701bdc4fef5a0d84dffbb2867 207 Gene3D G3DSA:3.40.50.720 2 191 1.3E-22 T 29-03-2018 SMALA_RS11325 d51b62c701bdc4fef5a0d84dffbb2867 207 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 4 93 2.9E-12 T 29-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal SMALA_RS11325 d51b62c701bdc4fef5a0d84dffbb2867 207 SUPERFAMILY SSF51735 4 186 4.44E-31 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS36480 adea2265184305026f2ef9495c51348b 635 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 4 579 2.8E-276 T 29-03-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613 SMALA_RS36480 adea2265184305026f2ef9495c51348b 635 Gene3D G3DSA:3.30.420.40 177 342 4.8E-49 T 29-03-2018 SMALA_RS36480 adea2265184305026f2ef9495c51348b 635 SUPERFAMILY SSF53067 167 358 1.05E-66 T 29-03-2018 SMALA_RS36480 adea2265184305026f2ef9495c51348b 635 Gene3D G3DSA:2.60.34.10 366 507 1.1E-69 T 29-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 SMALA_RS36480 adea2265184305026f2ef9495c51348b 635 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 172 185 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 SMALA_RS36480 adea2265184305026f2ef9495c51348b 635 SUPERFAMILY SSF100920 360 516 7.98E-59 T 29-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 SMALA_RS36480 adea2265184305026f2ef9495c51348b 635 Gene3D G3DSA:3.30.420.40 1 176 9.6E-66 T 29-03-2018 SMALA_RS36480 adea2265184305026f2ef9495c51348b 635 SUPERFAMILY SSF100934 483 589 7.06E-16 T 29-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain SMALA_RS36480 adea2265184305026f2ef9495c51348b 635 SUPERFAMILY SSF53067 2 164 5.96E-55 T 29-03-2018 SMALA_RS36480 adea2265184305026f2ef9495c51348b 635 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 622 35.867 T 29-03-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613 SMALA_RS36480 adea2265184305026f2ef9495c51348b 635 Pfam PF00012 Hsp70 protein 4 579 1.1E-242 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SMALA_RS36480 adea2265184305026f2ef9495c51348b 635 PRINTS PR00301 70kDa heat shock protein signature 341 361 1.4E-73 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SMALA_RS36480 adea2265184305026f2ef9495c51348b 635 PRINTS PR00301 70kDa heat shock protein signature 54 62 1.4E-73 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SMALA_RS36480 adea2265184305026f2ef9495c51348b 635 PRINTS PR00301 70kDa heat shock protein signature 3 16 1.4E-73 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SMALA_RS36480 adea2265184305026f2ef9495c51348b 635 PRINTS PR00301 70kDa heat shock protein signature 31 43 1.4E-73 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SMALA_RS36480 adea2265184305026f2ef9495c51348b 635 PRINTS PR00301 70kDa heat shock protein signature 445 461 1.4E-73 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SMALA_RS36480 adea2265184305026f2ef9495c51348b 635 PRINTS PR00301 70kDa heat shock protein signature 364 383 1.4E-73 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SMALA_RS36480 adea2265184305026f2ef9495c51348b 635 PRINTS PR00301 70kDa heat shock protein signature 178 188 1.4E-73 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SMALA_RS36480 adea2265184305026f2ef9495c51348b 635 PRINTS PR00301 70kDa heat shock protein signature 119 139 1.4E-73 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SMALA_RS36480 adea2265184305026f2ef9495c51348b 635 PRINTS PR00301 70kDa heat shock protein signature 310 326 1.4E-73 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SMALA_RS36480 adea2265184305026f2ef9495c51348b 635 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 SMALA_RS36480 adea2265184305026f2ef9495c51348b 635 Gene3D G3DSA:1.20.1270.10 508 592 2.0E-23 T 29-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain SMALA_RS37340 0eaa66338e76c223155e2212a1dd35d7 304 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 5.1E-23 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS37340 0eaa66338e76c223155e2212a1dd35d7 304 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 161 5.1E-23 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS37340 0eaa66338e76c223155e2212a1dd35d7 304 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 190 5.1E-23 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS37340 0eaa66338e76c223155e2212a1dd35d7 304 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 192 209 5.1E-23 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS37340 0eaa66338e76c223155e2212a1dd35d7 304 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 92 103 5.1E-23 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS37340 0eaa66338e76c223155e2212a1dd35d7 304 Gene3D G3DSA:3.40.50.720 2 264 1.3E-58 T 29-03-2018 SMALA_RS37340 0eaa66338e76c223155e2212a1dd35d7 304 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 171 190 3.6E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS37340 0eaa66338e76c223155e2212a1dd35d7 304 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 92 103 3.6E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS37340 0eaa66338e76c223155e2212a1dd35d7 304 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 159 3.6E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS37340 0eaa66338e76c223155e2212a1dd35d7 304 Pfam PF00106 short chain dehydrogenase 9 209 6.0E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS37340 0eaa66338e76c223155e2212a1dd35d7 304 SUPERFAMILY SSF51735 6 263 2.91E-56 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS37340 0eaa66338e76c223155e2212a1dd35d7 304 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 158 186 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMALA_RS16140 6acc5be2ed5ffae3c9e759dced8597bd 336 Gene3D G3DSA:3.40.50.1110 59 272 2.4E-27 T 29-03-2018 SMALA_RS16140 6acc5be2ed5ffae3c9e759dced8597bd 336 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 69 248 1.1E-20 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain SMALA_RS16140 6acc5be2ed5ffae3c9e759dced8597bd 336 SUPERFAMILY SSF52266 64 262 1.98E-30 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain SMALA_RS00580 87829a6b846958d55d53146820eda5d8 390 Gene3D G3DSA:3.40.50.1100 69 184 2.8E-27 T 29-03-2018 SMALA_RS00580 87829a6b846958d55d53146820eda5d8 390 SUPERFAMILY SSF53686 54 352 3.01E-55 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMALA_RS00580 87829a6b846958d55d53146820eda5d8 390 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 57 373 3.2E-62 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMALA_RS00580 87829a6b846958d55d53146820eda5d8 390 Gene3D G3DSA:3.40.50.1100 185 390 2.6E-31 T 29-03-2018 SMALA_RS12250 ad6fa775411ce05583aaa9d9f61fa511 261 Gene3D G3DSA:1.10.10.10 1 58 3.5E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS12250 ad6fa775411ce05583aaa9d9f61fa511 261 Pfam PF00455 DeoR C terminal sensor domain 86 239 2.7E-44 T 29-03-2018 IPR014036 DeoR C-terminal sensor domain SMALA_RS12250 ad6fa775411ce05583aaa9d9f61fa511 261 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 2.9E-8 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMALA_RS12250 ad6fa775411ce05583aaa9d9f61fa511 261 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 2.9E-8 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMALA_RS12250 ad6fa775411ce05583aaa9d9f61fa511 261 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 29-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 SMALA_RS12250 ad6fa775411ce05583aaa9d9f61fa511 261 SUPERFAMILY SSF46785 5 61 3.53E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS12250 ad6fa775411ce05583aaa9d9f61fa511 261 SMART SM00420 6 58 4.8E-15 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMALA_RS12250 ad6fa775411ce05583aaa9d9f61fa511 261 Pfam PF08220 DeoR-like helix-turn-helix domain 6 58 1.1E-16 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMALA_RS12250 ad6fa775411ce05583aaa9d9f61fa511 261 SUPERFAMILY SSF100950 85 241 3.85E-27 T 29-03-2018 SMALA_RS12250 ad6fa775411ce05583aaa9d9f61fa511 261 Gene3D G3DSA:3.40.50.1360 82 248 5.8E-34 T 29-03-2018 SMALA_RS12250 ad6fa775411ce05583aaa9d9f61fa511 261 SMART SM01134 82 242 5.7E-58 T 29-03-2018 SMALA_RS37880 879eb2953e1f3126a1871bcf2bc7ddc1 135 Pfam PF01042 Endoribonuclease L-PSP 15 133 9.9E-19 T 29-03-2018 IPR006175 YjgF/YER057c/UK114 family SMALA_RS37880 879eb2953e1f3126a1871bcf2bc7ddc1 135 SUPERFAMILY SSF55298 3 134 1.57E-26 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SMALA_RS37880 879eb2953e1f3126a1871bcf2bc7ddc1 135 Gene3D G3DSA:3.30.1330.40 6 135 2.5E-25 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SMALA_RS03915 8346a38397c605a176031909187d6cc5 230 Pfam PF13581 Histidine kinase-like ATPase domain 4 118 9.1E-10 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS03915 8346a38397c605a176031909187d6cc5 230 SUPERFAMILY SSF55874 29 119 6.02E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS03915 8346a38397c605a176031909187d6cc5 230 Gene3D G3DSA:3.30.565.10 1 134 3.5E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS31990 0324e4a9827470b454ac0add66bb9c20 440 Gene3D G3DSA:3.40.630.10 45 321 1.2E-34 T 29-03-2018 SMALA_RS31990 0324e4a9827470b454ac0add66bb9c20 440 SMART SM00631 48 275 0.0012 T 29-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 SMALA_RS31990 0324e4a9827470b454ac0add66bb9c20 440 SUPERFAMILY SSF53187 46 238 7.28E-38 T 29-03-2018 SMALA_RS31990 0324e4a9827470b454ac0add66bb9c20 440 Pfam PF00246 Zinc carboxypeptidase 58 207 1.1E-20 T 29-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 SMALA_RS25670 5073e85f516fa695e1354ce689d1bb78 325 SUPERFAMILY SSF161098 99 308 1.96E-15 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS25670 5073e85f516fa695e1354ce689d1bb78 325 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 124 323 9.5E-36 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS25670 5073e85f516fa695e1354ce689d1bb78 325 Gene3D G3DSA:1.10.3720.10 2 312 7.5E-37 T 29-03-2018 SMALA_RS20685 3e91df5181087acd3e52b4f85d1437c1 863 SUPERFAMILY SSF81923 4 157 8.44E-31 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 SMALA_RS20685 3e91df5181087acd3e52b4f85d1437c1 863 Gene3D G3DSA:1.10.1780.10 1 152 8.0E-30 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 SMALA_RS20685 3e91df5181087acd3e52b4f85d1437c1 863 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 637 655 - T 29-03-2018 IPR028299 ClpA/B, conserved site 2 SMALA_RS20685 3e91df5181087acd3e52b4f85d1437c1 863 Gene3D G3DSA:3.40.50.300 558 769 6.6E-49 T 29-03-2018 SMALA_RS20685 3e91df5181087acd3e52b4f85d1437c1 863 Gene3D G3DSA:3.40.50.300 158 344 5.6E-23 T 29-03-2018 SMALA_RS20685 3e91df5181087acd3e52b4f85d1437c1 863 SMART SM01086 770 859 4.5E-36 T 29-03-2018 IPR019489 Clp ATPase, C-terminal SMALA_RS20685 3e91df5181087acd3e52b4f85d1437c1 863 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 204 338 2.5E-11 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 SMALA_RS20685 3e91df5181087acd3e52b4f85d1437c1 863 Pfam PF07724 AAA domain (Cdc48 subfamily) 602 763 3.0E-52 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 SMALA_RS20685 3e91df5181087acd3e52b4f85d1437c1 863 Gene3D G3DSA:1.10.8.60 770 859 7.5E-24 T 29-03-2018 SMALA_RS20685 3e91df5181087acd3e52b4f85d1437c1 863 SUPERFAMILY SSF52540 158 551 5.87E-90 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS20685 3e91df5181087acd3e52b4f85d1437c1 863 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 770 850 3.8E-26 T 29-03-2018 IPR019489 Clp ATPase, C-terminal SMALA_RS20685 3e91df5181087acd3e52b4f85d1437c1 863 SUPERFAMILY SSF52540 552 853 5.13E-76 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS20685 3e91df5181087acd3e52b4f85d1437c1 863 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 5 857 0.0 T 29-03-2018 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0016485 SMALA_RS20685 3e91df5181087acd3e52b4f85d1437c1 863 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 714 728 5.0E-42 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 SMALA_RS20685 3e91df5181087acd3e52b4f85d1437c1 863 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 607 625 5.0E-42 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 SMALA_RS20685 3e91df5181087acd3e52b4f85d1437c1 863 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 652 670 5.0E-42 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 SMALA_RS20685 3e91df5181087acd3e52b4f85d1437c1 863 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 681 699 5.0E-42 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 SMALA_RS20685 3e91df5181087acd3e52b4f85d1437c1 863 Gene3D G3DSA:1.10.8.60 345 553 8.0E-45 T 29-03-2018 SMALA_RS20685 3e91df5181087acd3e52b4f85d1437c1 863 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 16 68 3.7E-4 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 SMALA_RS20685 3e91df5181087acd3e52b4f85d1437c1 863 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 95 146 5.4E-12 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 SMALA_RS20685 3e91df5181087acd3e52b4f85d1437c1 863 SMART SM00382 199 346 4.2E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS20685 3e91df5181087acd3e52b4f85d1437c1 863 SMART SM00382 603 796 1.4E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS20685 3e91df5181087acd3e52b4f85d1437c1 863 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 296 308 - T 29-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 SMALA_RS03180 5be9e6ed1875053e39ec109c9bc377d9 309 SMART SM00342 219 302 9.4E-28 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS03180 5be9e6ed1875053e39ec109c9bc377d9 309 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 271 286 3.4E-6 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SMALA_RS03180 5be9e6ed1875053e39ec109c9bc377d9 309 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 286 302 3.4E-6 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SMALA_RS03180 5be9e6ed1875053e39ec109c9bc377d9 309 Gene3D G3DSA:1.10.10.60 259 308 2.1E-12 T 29-03-2018 SMALA_RS03180 5be9e6ed1875053e39ec109c9bc377d9 309 Gene3D G3DSA:2.60.120.280 31 184 3.4E-8 T 29-03-2018 SMALA_RS03180 5be9e6ed1875053e39ec109c9bc377d9 309 Pfam PF12833 Helix-turn-helix domain 225 303 1.1E-18 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS03180 5be9e6ed1875053e39ec109c9bc377d9 309 SUPERFAMILY SSF46689 255 304 2.02E-10 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS03180 5be9e6ed1875053e39ec109c9bc377d9 309 Gene3D G3DSA:1.10.10.60 185 258 4.1E-10 T 29-03-2018 SMALA_RS03180 5be9e6ed1875053e39ec109c9bc377d9 309 Pfam PF12852 Cupin 6 187 2.4E-33 T 29-03-2018 IPR032783 AraC-type transcription regulator, ligand-binding domain SMALA_RS03180 5be9e6ed1875053e39ec109c9bc377d9 309 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 256 298 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 SMALA_RS03180 5be9e6ed1875053e39ec109c9bc377d9 309 SUPERFAMILY SSF46689 204 253 6.09E-7 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS22165 fb844c8f673dcd96761b1c93ec0f7607 554 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 147 166 4.7E-28 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS22165 fb844c8f673dcd96761b1c93ec0f7607 554 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 188 212 4.7E-28 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS22165 fb844c8f673dcd96761b1c93ec0f7607 554 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 269 293 4.7E-28 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS22165 fb844c8f673dcd96761b1c93ec0f7607 554 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 357 376 4.7E-28 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS22165 fb844c8f673dcd96761b1c93ec0f7607 554 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 409 435 4.7E-28 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS22165 fb844c8f673dcd96761b1c93ec0f7607 554 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 6 517 7.5E-176 T 29-03-2018 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS22165 fb844c8f673dcd96761b1c93ec0f7607 554 Pfam PF00361 Proton-conducting membrane transporter 141 451 2.6E-67 T 29-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS29490 c07166bd73bed1fc12fbf80cd1f8619a 396 Gene3D G3DSA:1.10.630.10 3 395 4.2E-68 T 29-03-2018 SMALA_RS29490 c07166bd73bed1fc12fbf80cd1f8619a 396 PRINTS PR00359 B-class P450 signature 130 146 4.5E-55 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS29490 c07166bd73bed1fc12fbf80cd1f8619a 396 PRINTS PR00359 B-class P450 signature 147 162 4.5E-55 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS29490 c07166bd73bed1fc12fbf80cd1f8619a 396 PRINTS PR00359 B-class P450 signature 187 209 4.5E-55 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS29490 c07166bd73bed1fc12fbf80cd1f8619a 396 PRINTS PR00359 B-class P450 signature 84 95 4.5E-55 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS29490 c07166bd73bed1fc12fbf80cd1f8619a 396 PRINTS PR00359 B-class P450 signature 343 354 4.5E-55 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS29490 c07166bd73bed1fc12fbf80cd1f8619a 396 PRINTS PR00359 B-class P450 signature 285 312 4.5E-55 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS29490 c07166bd73bed1fc12fbf80cd1f8619a 396 PRINTS PR00359 B-class P450 signature 268 279 4.5E-55 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS29490 c07166bd73bed1fc12fbf80cd1f8619a 396 PRINTS PR00359 B-class P450 signature 334 343 4.5E-55 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS29490 c07166bd73bed1fc12fbf80cd1f8619a 396 PRINTS PR00359 B-class P450 signature 313 328 4.5E-55 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS29490 c07166bd73bed1fc12fbf80cd1f8619a 396 Pfam PF00067 Cytochrome P450 179 378 1.6E-26 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS29490 c07166bd73bed1fc12fbf80cd1f8619a 396 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 336 345 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMALA_RS29490 c07166bd73bed1fc12fbf80cd1f8619a 396 SUPERFAMILY SSF48264 17 395 3.14E-89 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS12350 92087f867d14df80844c6f817dc27336 499 PIRSF PIRSF000538 1 472 1.7E-64 T 29-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 SMALA_RS12350 92087f867d14df80844c6f817dc27336 499 Gene3D G3DSA:3.30.420.40 1 236 1.2E-50 T 29-03-2018 SMALA_RS12350 92087f867d14df80844c6f817dc27336 499 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 4 231 1.2E-33 T 29-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 SMALA_RS12350 92087f867d14df80844c6f817dc27336 499 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 241 423 8.6E-19 T 29-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 SMALA_RS12350 92087f867d14df80844c6f817dc27336 499 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 335 356 - T 29-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 SMALA_RS12350 92087f867d14df80844c6f817dc27336 499 Gene3D G3DSA:3.30.420.40 237 470 5.0E-40 T 29-03-2018 SMALA_RS12350 92087f867d14df80844c6f817dc27336 499 SUPERFAMILY SSF53067 238 452 1.02E-32 T 29-03-2018 SMALA_RS12350 92087f867d14df80844c6f817dc27336 499 SUPERFAMILY SSF53067 4 235 1.78E-34 T 29-03-2018 SMALA_RS02740 abe822e16dda7c4149bcfa671dd67dc4 414 SUPERFAMILY SSF55874 255 385 5.72E-13 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS02740 abe822e16dda7c4149bcfa671dd67dc4 414 Pfam PF07730 Histidine kinase 178 245 3.2E-16 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMALA_RS02740 abe822e16dda7c4149bcfa671dd67dc4 414 Gene3D G3DSA:3.30.565.10 253 387 6.7E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS23640 cc4f3760984f4c483263b91209a3ec9a 216 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 70 8.0E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS23640 cc4f3760984f4c483263b91209a3ec9a 216 SUPERFAMILY SSF46689 14 94 1.8E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS23640 cc4f3760984f4c483263b91209a3ec9a 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 39 1.9E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS23640 cc4f3760984f4c483263b91209a3ec9a 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 1.9E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS23640 cc4f3760984f4c483263b91209a3ec9a 216 SUPERFAMILY SSF48498 92 199 5.48E-30 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS23640 cc4f3760984f4c483263b91209a3ec9a 216 Gene3D G3DSA:1.10.357.10 14 208 2.4E-32 T 29-03-2018 SMALA_RS16435 bcb005b3f54452c1a7ebfc07d300cf03 213 SUPERFAMILY SSF52540 6 152 1.28E-11 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS16435 bcb005b3f54452c1a7ebfc07d300cf03 213 PRINTS PR00988 Uridine kinase signature 79 94 3.4E-7 T 29-03-2018 SMALA_RS16435 bcb005b3f54452c1a7ebfc07d300cf03 213 PRINTS PR00988 Uridine kinase signature 139 149 3.4E-7 T 29-03-2018 SMALA_RS16435 bcb005b3f54452c1a7ebfc07d300cf03 213 PRINTS PR00988 Uridine kinase signature 8 25 3.4E-7 T 29-03-2018 SMALA_RS16435 bcb005b3f54452c1a7ebfc07d300cf03 213 Gene3D G3DSA:3.40.50.300 1 20 4.2E-4 T 29-03-2018 SMALA_RS16435 bcb005b3f54452c1a7ebfc07d300cf03 213 Gene3D G3DSA:3.40.50.300 21 168 9.2E-21 T 29-03-2018 SMALA_RS11225 f76c124e5090742a6d00d33b95e99fe0 201 SUPERFAMILY SSF51064 146 199 2.35E-12 T 29-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 SMALA_RS11225 f76c124e5090742a6d00d33b95e99fe0 201 Pfam PF01025 GrpE 57 199 3.9E-33 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 SMALA_RS11225 f76c124e5090742a6d00d33b95e99fe0 201 Gene3D G3DSA:2.30.22.10 143 199 1.6E-17 T 29-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 SMALA_RS11225 f76c124e5090742a6d00d33b95e99fe0 201 Gene3D G3DSA:3.90.20.20 48 142 2.8E-19 T 29-03-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 SMALA_RS11225 f76c124e5090742a6d00d33b95e99fe0 201 Hamap MF_01151 Protein GrpE [grpE]. 6 199 16.346 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 SMALA_RS11225 f76c124e5090742a6d00d33b95e99fe0 201 SUPERFAMILY SSF58014 56 143 1.83E-19 T 29-03-2018 SMALA_RS11225 f76c124e5090742a6d00d33b95e99fe0 201 PRINTS PR00773 GrpE protein signature 99 114 1.6E-16 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 SMALA_RS11225 f76c124e5090742a6d00d33b95e99fe0 201 PRINTS PR00773 GrpE protein signature 178 197 1.6E-16 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 SMALA_RS11225 f76c124e5090742a6d00d33b95e99fe0 201 PRINTS PR00773 GrpE protein signature 151 166 1.6E-16 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 SMALA_RS11225 f76c124e5090742a6d00d33b95e99fe0 201 PRINTS PR00773 GrpE protein signature 71 87 1.6E-16 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 SMALA_RS25490 10c9b713b831d6bbc8eb4d17bcca40a9 357 Gene3D G3DSA:3.30.420.40 141 336 1.7E-48 T 29-03-2018 SMALA_RS25490 10c9b713b831d6bbc8eb4d17bcca40a9 357 SUPERFAMILY SSF53067 22 325 1.3E-52 T 29-03-2018 SMALA_RS25490 10c9b713b831d6bbc8eb4d17bcca40a9 357 Pfam PF00480 ROK family 23 324 1.7E-54 T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 SMALA_RS25490 10c9b713b831d6bbc8eb4d17bcca40a9 357 ProSitePatterns PS01125 ROK family signature. 155 182 - T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 SMALA_RS25490 10c9b713b831d6bbc8eb4d17bcca40a9 357 Gene3D G3DSA:3.30.420.40 12 140 7.2E-22 T 29-03-2018 SMALA_RS11340 dc5e493fe1f82a86cca95fdd7b79c377 219 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 21 216 2.3E-76 T 29-03-2018 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 SMALA_RS11340 dc5e493fe1f82a86cca95fdd7b79c377 219 Gene3D G3DSA:3.20.20.70 16 217 8.4E-30 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS11340 dc5e493fe1f82a86cca95fdd7b79c377 219 ProSitePatterns PS00160 KDPG and KHG aldolases Schiff-base forming residue. 135 148 - T 29-03-2018 IPR031338 KDPG/KHG aldolase, active site 2 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 SMALA_RS11340 dc5e493fe1f82a86cca95fdd7b79c377 219 Pfam PF01081 KDPG and KHG aldolase 19 209 1.3E-69 T 29-03-2018 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 SMALA_RS11340 dc5e493fe1f82a86cca95fdd7b79c377 219 ProSitePatterns PS00159 KDPG and KHG aldolases active site. 47 56 - T 29-03-2018 IPR031337 KDPG/KHG aldolase, active site 1 KEGG: 00030+4.1.2.14|KEGG: 00330+4.1.3.16|KEGG: 00630+4.1.3.16|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 SMALA_RS11340 dc5e493fe1f82a86cca95fdd7b79c377 219 SUPERFAMILY SSF51569 21 216 6.41E-66 T 29-03-2018 SMALA_RS06675 433550c822057870950ce24d6e85fa12 228 Gene3D G3DSA:1.10.260.40 42 72 1.1E-10 T 29-03-2018 SMALA_RS06675 433550c822057870950ce24d6e85fa12 228 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 66 7.6E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS06675 433550c822057870950ce24d6e85fa12 228 Gene3D G3DSA:1.10.10.60 7 41 5.0E-11 T 29-03-2018 SMALA_RS06675 433550c822057870950ce24d6e85fa12 228 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 1.1E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS06675 433550c822057870950ce24d6e85fa12 228 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 1.1E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS06675 433550c822057870950ce24d6e85fa12 228 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 77 215 5.8E-40 T 29-03-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 SMALA_RS06675 433550c822057870950ce24d6e85fa12 228 SUPERFAMILY SSF48498 77 216 1.1E-33 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS06675 433550c822057870950ce24d6e85fa12 228 PRINTS PR00400 Tetracycline repressor protein signature 83 102 1.4E-21 T 29-03-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 SMALA_RS06675 433550c822057870950ce24d6e85fa12 228 PRINTS PR00400 Tetracycline repressor protein signature 139 158 1.4E-21 T 29-03-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 SMALA_RS06675 433550c822057870950ce24d6e85fa12 228 PRINTS PR00400 Tetracycline repressor protein signature 199 213 1.4E-21 T 29-03-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 SMALA_RS06675 433550c822057870950ce24d6e85fa12 228 PRINTS PR00400 Tetracycline repressor protein signature 103 126 1.4E-21 T 29-03-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 SMALA_RS06675 433550c822057870950ce24d6e85fa12 228 PRINTS PR00400 Tetracycline repressor protein signature 32 55 1.4E-21 T 29-03-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 SMALA_RS06675 433550c822057870950ce24d6e85fa12 228 SUPERFAMILY SSF46689 9 74 5.99E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS06675 433550c822057870950ce24d6e85fa12 228 Gene3D G3DSA:1.10.357.10 73 219 3.6E-31 T 29-03-2018 SMALA_RS19000 4cbd137d661c8d3bfb25d6cd03cd06b9 507 SUPERFAMILY SSF51735 1 260 1.8E-49 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS19000 4cbd137d661c8d3bfb25d6cd03cd06b9 507 Pfam PF13460 NAD(P)H-binding 4 147 4.2E-22 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS19000 4cbd137d661c8d3bfb25d6cd03cd06b9 507 Gene3D G3DSA:3.30.530.20 333 492 6.5E-11 T 29-03-2018 IPR023393 START-like domain SMALA_RS19000 4cbd137d661c8d3bfb25d6cd03cd06b9 507 SUPERFAMILY SSF55961 338 484 1.84E-9 T 29-03-2018 SMALA_RS19000 4cbd137d661c8d3bfb25d6cd03cd06b9 507 Pfam PF11066 Protein of unknown function (DUF2867) 329 474 9.8E-41 T 29-03-2018 IPR021295 Protein of unknown function DUF2867 SMALA_RS19000 4cbd137d661c8d3bfb25d6cd03cd06b9 507 Gene3D G3DSA:3.40.50.720 1 321 1.1E-33 T 29-03-2018 SMALA_RS15520 a56bcc2ff68b3913a8f8289bfc823d49 229 Gene3D G3DSA:3.40.50.300 1 225 1.1E-68 T 29-03-2018 SMALA_RS15520 a56bcc2ff68b3913a8f8289bfc823d49 229 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS15520 a56bcc2ff68b3913a8f8289bfc823d49 229 SMART SM00382 28 215 3.9E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS15520 a56bcc2ff68b3913a8f8289bfc823d49 229 SUPERFAMILY SSF52540 1 221 3.86E-70 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS15520 a56bcc2ff68b3913a8f8289bfc823d49 229 Pfam PF00005 ABC transporter 19 166 2.7E-34 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS15520 a56bcc2ff68b3913a8f8289bfc823d49 229 TIGRFAM TIGR02673 FtsE: cell division ATP-binding protein FtsE 1 215 1.2E-86 T 29-03-2018 IPR005286 Cell division protein FtsE, ATP-binding GO:0005524|GO:0051301 SMALA_RS03500 1befe325f08593e07ec0728dde4d2388 120 Pfam PF00355 Rieske [2Fe-2S] domain 2 87 1.7E-17 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMALA_RS03500 1befe325f08593e07ec0728dde4d2388 120 SUPERFAMILY SSF50022 2 100 1.44E-30 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMALA_RS03500 1befe325f08593e07ec0728dde4d2388 120 Gene3D G3DSA:2.102.10.10 1 117 1.3E-26 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMALA_RS16315 a9238aca9bc139fcdfa4d191d38d1f7c 399 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 207 361 5.5E-24 T 29-03-2018 IPR000160 GGDEF domain SMALA_RS16315 a9238aca9bc139fcdfa4d191d38d1f7c 399 SUPERFAMILY SSF55073 214 362 1.8E-28 T 29-03-2018 IPR029787 Nucleotide cyclase SMALA_RS16315 a9238aca9bc139fcdfa4d191d38d1f7c 399 SUPERFAMILY SSF55781 33 199 1.16E-13 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS16315 a9238aca9bc139fcdfa4d191d38d1f7c 399 Gene3D G3DSA:3.30.70.270 206 369 8.2E-37 T 29-03-2018 SMALA_RS16315 a9238aca9bc139fcdfa4d191d38d1f7c 399 Gene3D G3DSA:3.30.450.40 13 205 8.6E-25 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS16315 a9238aca9bc139fcdfa4d191d38d1f7c 399 SMART SM00065 32 206 0.0061 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS16315 a9238aca9bc139fcdfa4d191d38d1f7c 399 SMART SM00267 198 368 1.9E-43 T 29-03-2018 IPR000160 GGDEF domain SMALA_RS16315 a9238aca9bc139fcdfa4d191d38d1f7c 399 Pfam PF01590 GAF domain 137 192 3.4E-5 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS16315 a9238aca9bc139fcdfa4d191d38d1f7c 399 Pfam PF00990 Diguanylate cyclase, GGDEF domain 209 361 1.5E-25 T 29-03-2018 IPR000160 GGDEF domain SMALA_RS36415 5a13b73152413ef2edacac4b222732c4 495 Gene3D G3DSA:3.40.605.10 1 268 4.6E-102 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS36415 5a13b73152413ef2edacac4b222732c4 495 SUPERFAMILY SSF53720 4 482 3.14E-171 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMALA_RS36415 5a13b73152413ef2edacac4b222732c4 495 Gene3D G3DSA:3.40.309.10 269 464 4.6E-74 T 29-03-2018 SMALA_RS36415 5a13b73152413ef2edacac4b222732c4 495 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 252 259 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 SMALA_RS36415 5a13b73152413ef2edacac4b222732c4 495 Pfam PF00171 Aldehyde dehydrogenase family 15 478 1.5E-176 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS36415 5a13b73152413ef2edacac4b222732c4 495 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 280 291 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 SMALA_RS34645 65b332adb053a512d7e6dcfc2db866d9 406 Pfam PF00480 ROK family 107 385 9.8E-37 T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 SMALA_RS34645 65b332adb053a512d7e6dcfc2db866d9 406 SUPERFAMILY SSF53067 104 390 1.03E-44 T 29-03-2018 SMALA_RS34645 65b332adb053a512d7e6dcfc2db866d9 406 Gene3D G3DSA:3.30.420.40 229 392 1.1E-34 T 29-03-2018 SMALA_RS34645 65b332adb053a512d7e6dcfc2db866d9 406 Gene3D G3DSA:3.30.420.40 91 228 4.4E-33 T 29-03-2018 SMALA_RS34645 65b332adb053a512d7e6dcfc2db866d9 406 SUPERFAMILY SSF46785 46 98 2.13E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS34645 65b332adb053a512d7e6dcfc2db866d9 406 Gene3D G3DSA:1.10.10.10 10 90 6.5E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS42075 cf57d87729a51d2d0cf499c8c7390b81 466 SUPERFAMILY SSF52777 209 450 1.78E-34 T 29-03-2018 SMALA_RS42075 cf57d87729a51d2d0cf499c8c7390b81 466 Pfam PF00668 Condensation domain 25 458 6.0E-55 T 29-03-2018 IPR001242 Condensation domain SMALA_RS42075 cf57d87729a51d2d0cf499c8c7390b81 466 SUPERFAMILY SSF52777 28 203 5.89E-35 T 29-03-2018 SMALA_RS42075 cf57d87729a51d2d0cf499c8c7390b81 466 Gene3D G3DSA:3.30.559.10 5 207 3.9E-33 T 29-03-2018 SMALA_RS02195 41144735a69904ed0f37ff354dedeada 208 Pfam PF08808 RES domain 14 178 1.4E-23 T 29-03-2018 IPR014914 RES domain SMALA_RS02195 41144735a69904ed0f37ff354dedeada 208 SMART SM00953 27 173 2.9E-7 T 29-03-2018 IPR014914 RES domain SMALA_RS04075 8b8923756eeeac8ef288b8be654e4e41 243 SMART SM00563 38 152 3.8E-34 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SMALA_RS04075 8b8923756eeeac8ef288b8be654e4e41 243 SUPERFAMILY SSF69593 19 205 4.32E-37 T 29-03-2018 SMALA_RS04075 8b8923756eeeac8ef288b8be654e4e41 243 Gene3D G3DSA:3.40.1130.10 6 213 2.4E-46 T 29-03-2018 SMALA_RS04075 8b8923756eeeac8ef288b8be654e4e41 243 Pfam PF01553 Acyltransferase 24 149 4.1E-28 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SMALA_RS20540 256a0076267ec06ae25e87976eb0d023 275 Gene3D G3DSA:3.40.50.1820 1 275 2.4E-57 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS20540 256a0076267ec06ae25e87976eb0d023 275 PRINTS PR00412 Epoxide hydrolase signature 27 45 6.4E-5 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS20540 256a0076267ec06ae25e87976eb0d023 275 PRINTS PR00412 Epoxide hydrolase signature 214 230 6.4E-5 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS20540 256a0076267ec06ae25e87976eb0d023 275 PRINTS PR00412 Epoxide hydrolase signature 47 62 6.4E-5 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS20540 256a0076267ec06ae25e87976eb0d023 275 SUPERFAMILY SSF53474 5 274 7.97E-60 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS20540 256a0076267ec06ae25e87976eb0d023 275 Pfam PF00561 alpha/beta hydrolase fold 22 257 7.6E-23 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS20540 256a0076267ec06ae25e87976eb0d023 275 PRINTS PR00111 Alpha/beta hydrolase fold signature 91 104 1.1E-10 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS20540 256a0076267ec06ae25e87976eb0d023 275 PRINTS PR00111 Alpha/beta hydrolase fold signature 216 230 1.1E-10 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS20540 256a0076267ec06ae25e87976eb0d023 275 PRINTS PR00111 Alpha/beta hydrolase fold signature 47 62 1.1E-10 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS28410 db2125276ba4f475c360d66dda13abcd 644 SUPERFAMILY SSF47203 278 437 1.34E-35 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMALA_RS28410 db2125276ba4f475c360d66dda13abcd 644 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 60 165 1.2E-18 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS28410 db2125276ba4f475c360d66dda13abcd 644 Gene3D G3DSA:2.40.110.10 169 268 6.9E-33 T 29-03-2018 SMALA_RS28410 db2125276ba4f475c360d66dda13abcd 644 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 170 266 4.6E-21 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 SMALA_RS28410 db2125276ba4f475c360d66dda13abcd 644 SUPERFAMILY SSF56645 34 288 6.94E-59 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMALA_RS28410 db2125276ba4f475c360d66dda13abcd 644 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 278 436 2.7E-30 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMALA_RS28410 db2125276ba4f475c360d66dda13abcd 644 Gene3D G3DSA:1.20.140.10 489 589 0.015 T 29-03-2018 SMALA_RS28410 db2125276ba4f475c360d66dda13abcd 644 Gene3D G3DSA:1.10.540.10 19 168 1.9E-27 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS28410 db2125276ba4f475c360d66dda13abcd 644 Gene3D G3DSA:1.20.140.10 269 447 2.6E-43 T 29-03-2018 SMALA_RS31110 40f51eb9ca3f92d70684522418d71e74 545 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 316 332 5.9E-40 T 29-03-2018 SMALA_RS31110 40f51eb9ca3f92d70684522418d71e74 545 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 334 352 5.9E-40 T 29-03-2018 SMALA_RS31110 40f51eb9ca3f92d70684522418d71e74 545 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 12 34 5.9E-40 T 29-03-2018 SMALA_RS31110 40f51eb9ca3f92d70684522418d71e74 545 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 301 316 5.9E-40 T 29-03-2018 SMALA_RS31110 40f51eb9ca3f92d70684522418d71e74 545 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 171 186 5.9E-40 T 29-03-2018 SMALA_RS31110 40f51eb9ca3f92d70684522418d71e74 545 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 352 368 5.9E-40 T 29-03-2018 SMALA_RS31110 40f51eb9ca3f92d70684522418d71e74 545 Gene3D G3DSA:3.50.50.60 6 474 4.2E-52 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS31110 40f51eb9ca3f92d70684522418d71e74 545 Pfam PF01494 FAD binding domain 11 365 1.7E-107 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 SMALA_RS31110 40f51eb9ca3f92d70684522418d71e74 545 SUPERFAMILY SSF51905 11 192 1.4E-53 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS31110 40f51eb9ca3f92d70684522418d71e74 545 SUPERFAMILY SSF51905 288 372 1.4E-53 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS34800 b3e12a5504af1ebe0b7e90b0d36e1ef3 101 Hamap MF_01954 Urease subunit beta [ureB]. 1 101 30.563 T 29-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMALA_RS34800 b3e12a5504af1ebe0b7e90b0d36e1ef3 101 Gene3D G3DSA:2.10.150.10 1 101 5.4E-44 T 29-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMALA_RS34800 b3e12a5504af1ebe0b7e90b0d36e1ef3 101 TIGRFAM TIGR00192 urease_beta: urease, beta subunit 1 98 1.8E-36 T 29-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMALA_RS34800 b3e12a5504af1ebe0b7e90b0d36e1ef3 101 Pfam PF00699 Urease beta subunit 3 99 1.7E-40 T 29-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMALA_RS34800 b3e12a5504af1ebe0b7e90b0d36e1ef3 101 SUPERFAMILY SSF51278 1 101 1.31E-43 T 29-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMALA_RS36560 c4da645850bcdd3f097c43607ef0d36c 472 Gene3D G3DSA:3.40.50.720 2 152 1.9E-28 T 29-03-2018 SMALA_RS36560 c4da645850bcdd3f097c43607ef0d36c 472 SUPERFAMILY SSF51735 6 165 6.19E-35 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS36560 c4da645850bcdd3f097c43607ef0d36c 472 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 9 134 9.1E-15 T 29-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 SMALA_RS36560 c4da645850bcdd3f097c43607ef0d36c 472 Gene3D G3DSA:3.30.360.10 153 472 2.3E-44 T 29-03-2018 SMALA_RS36560 c4da645850bcdd3f097c43607ef0d36c 472 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 148 225 7.8E-19 T 29-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 SMALA_RS36560 c4da645850bcdd3f097c43607ef0d36c 472 SUPERFAMILY SSF55347 139 224 9.16E-29 T 29-03-2018 SMALA_RS36560 c4da645850bcdd3f097c43607ef0d36c 472 SUPERFAMILY SSF55347 279 340 9.16E-29 T 29-03-2018 SMALA_RS18090 66e9c8eb860c9e5720c5edf29dfbf95b 161 Gene3D G3DSA:3.10.450.50 3 149 3.8E-38 T 29-03-2018 SMALA_RS18090 66e9c8eb860c9e5720c5edf29dfbf95b 161 SUPERFAMILY SSF54427 3 138 2.08E-38 T 29-03-2018 IPR032710 NTF2-like domain SMALA_RS18090 66e9c8eb860c9e5720c5edf29dfbf95b 161 Pfam PF13474 SnoaL-like domain 12 138 1.9E-30 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain SMALA_RS07690 1755d8b44503bae48df386996dc9daef 230 Pfam PF08666 SAF domain 65 118 1.3E-4 T 29-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 SMALA_RS07690 1755d8b44503bae48df386996dc9daef 230 SMART SM00858 64 125 2.9E-5 T 29-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 SMALA_RS07690 1755d8b44503bae48df386996dc9daef 230 Gene3D G3DSA:3.90.1210.10 60 130 4.4E-10 T 29-03-2018 SMALA_RS35145 698b3de6fec9b258aecdfddc580fc2f8 177 Gene3D G3DSA:3.40.190.10 20 167 1.1E-7 T 29-03-2018 SMALA_RS13015 0c632d409063f09683badb7a2d154908 746 Pfam PF03772 Competence protein 150 424 7.6E-41 T 29-03-2018 IPR004477 ComEC/Rec2-related protein SMALA_RS13015 0c632d409063f09683badb7a2d154908 746 SMART SM00849 473 669 1.5E-7 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS13015 0c632d409063f09683badb7a2d154908 746 Pfam PF00753 Metallo-beta-lactamase superfamily 471 650 1.2E-9 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS13015 0c632d409063f09683badb7a2d154908 746 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 172 348 2.9E-11 T 29-03-2018 IPR004477 ComEC/Rec2-related protein SMALA_RS13015 0c632d409063f09683badb7a2d154908 746 Gene3D G3DSA:3.60.15.10 463 694 1.9E-31 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS13015 0c632d409063f09683badb7a2d154908 746 SUPERFAMILY SSF56281 459 706 3.8E-35 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS03245 acc7d6ff6012495e764ff04f0a14561e 155 Gene3D G3DSA:2.30.110.10 8 153 1.9E-32 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS03245 acc7d6ff6012495e764ff04f0a14561e 155 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 15 101 9.8E-20 T 29-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 SMALA_RS03245 acc7d6ff6012495e764ff04f0a14561e 155 SUPERFAMILY SSF50475 7 150 2.86E-33 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS37490 109db748bcb794d3b96836a81bd9bd69 202 ProSitePatterns PS01081 TetR-type HTH domain signature. 39 70 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site SMALA_RS37490 109db748bcb794d3b96836a81bd9bd69 202 SUPERFAMILY SSF46689 16 91 9.45E-18 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS37490 109db748bcb794d3b96836a81bd9bd69 202 Gene3D G3DSA:1.10.357.10 71 202 3.8E-27 T 29-03-2018 SMALA_RS37490 109db748bcb794d3b96836a81bd9bd69 202 Gene3D G3DSA:1.10.10.60 1 70 2.6E-20 T 29-03-2018 SMALA_RS37490 109db748bcb794d3b96836a81bd9bd69 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 48 71 2.4E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS37490 109db748bcb794d3b96836a81bd9bd69 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 40 2.4E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS37490 109db748bcb794d3b96836a81bd9bd69 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 70 2.0E-19 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS14640 6695aa3cab93822d6c9c7f545811a88b 284 Pfam PF12697 Alpha/beta hydrolase family 26 271 1.4E-11 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS14640 6695aa3cab93822d6c9c7f545811a88b 284 Gene3D G3DSA:3.40.50.1820 1 283 1.5E-28 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS14640 6695aa3cab93822d6c9c7f545811a88b 284 SUPERFAMILY SSF53474 4 277 1.66E-38 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS14435 324ceebdd4ba78108fe7d9f6683d3f5a 465 Gene3D G3DSA:3.30.565.10 290 440 1.7E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS14435 324ceebdd4ba78108fe7d9f6683d3f5a 465 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 337 436 9.7E-9 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS14435 324ceebdd4ba78108fe7d9f6683d3f5a 465 PRINTS PR00344 Bacterial sensor protein C-terminal signature 398 416 3.1E-7 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS14435 324ceebdd4ba78108fe7d9f6683d3f5a 465 PRINTS PR00344 Bacterial sensor protein C-terminal signature 370 384 3.1E-7 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS14435 324ceebdd4ba78108fe7d9f6683d3f5a 465 SMART SM00387 330 438 1.9E-10 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS14435 324ceebdd4ba78108fe7d9f6683d3f5a 465 SMART SM00388 229 287 8.2E-6 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS14435 324ceebdd4ba78108fe7d9f6683d3f5a 465 SMART SM00304 176 228 2.6E-12 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMALA_RS14435 324ceebdd4ba78108fe7d9f6683d3f5a 465 SUPERFAMILY SSF55874 291 434 4.58E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS14435 324ceebdd4ba78108fe7d9f6683d3f5a 465 Pfam PF00672 HAMP domain 177 224 7.0E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMALA_RS14435 324ceebdd4ba78108fe7d9f6683d3f5a 465 SUPERFAMILY SSF158472 177 225 1.44E-5 T 29-03-2018 SMALA_RS14435 324ceebdd4ba78108fe7d9f6683d3f5a 465 SUPERFAMILY SSF47384 213 282 2.94E-9 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS14435 324ceebdd4ba78108fe7d9f6683d3f5a 465 Gene3D G3DSA:1.10.287.130 219 288 6.9E-7 T 29-03-2018 SMALA_RS14435 324ceebdd4ba78108fe7d9f6683d3f5a 465 Pfam PF00512 His Kinase A (phospho-acceptor) domain 230 279 8.9E-9 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS10240 390b62f2da11da7477a1691aa7d880ee 586 Gene3D G3DSA:3.40.1190.10 165 404 7.9E-59 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMALA_RS10240 390b62f2da11da7477a1691aa7d880ee 586 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 64 557 33.053 T 29-03-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 SMALA_RS10240 390b62f2da11da7477a1691aa7d880ee 586 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 85 557 7.4E-141 T 29-03-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 SMALA_RS10240 390b62f2da11da7477a1691aa7d880ee 586 Pfam PF02875 Mur ligase family, glutamate ligase domain 400 484 3.8E-18 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 SMALA_RS10240 390b62f2da11da7477a1691aa7d880ee 586 SUPERFAMILY SSF63418 79 163 4.32E-20 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 SMALA_RS10240 390b62f2da11da7477a1691aa7d880ee 586 SUPERFAMILY SSF53623 165 399 7.2E-65 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMALA_RS10240 390b62f2da11da7477a1691aa7d880ee 586 SUPERFAMILY SSF53244 400 557 3.01E-43 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 SMALA_RS10240 390b62f2da11da7477a1691aa7d880ee 586 Gene3D G3DSA:3.90.190.20 405 574 2.4E-44 T 29-03-2018 SMALA_RS10240 390b62f2da11da7477a1691aa7d880ee 586 Gene3D G3DSA:3.40.1390.10 63 164 2.0E-25 T 29-03-2018 SMALA_RS10240 390b62f2da11da7477a1691aa7d880ee 586 Pfam PF08245 Mur ligase middle domain 174 379 1.5E-49 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMALA_RS10240 390b62f2da11da7477a1691aa7d880ee 586 Pfam PF01225 Mur ligase family, catalytic domain 86 160 3.8E-12 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 SMALA_RS25580 65f39df16185e0a4ce2fb30a0582cde9 326 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 43 80 9.0E-7 T 29-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain SMALA_RS25580 65f39df16185e0a4ce2fb30a0582cde9 326 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 142 326 5.1E-28 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS25580 65f39df16185e0a4ce2fb30a0582cde9 326 SUPERFAMILY SSF161098 120 309 1.3E-21 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS25580 65f39df16185e0a4ce2fb30a0582cde9 326 Gene3D G3DSA:1.10.3720.10 48 315 1.3E-42 T 29-03-2018 SMALA_RS13215 d9afc750bb1a2be579464d797dc1067a 284 SUPERFAMILY SSF81995 6 75 6.54E-5 T 29-03-2018 SMALA_RS33370 0d427fd66e1576fe70d892bfed719527 322 Gene3D G3DSA:3.40.50.720 2 173 3.5E-31 T 29-03-2018 SMALA_RS33370 0d427fd66e1576fe70d892bfed719527 322 Gene3D G3DSA:3.90.25.10 174 319 2.1E-35 T 29-03-2018 SMALA_RS33370 0d427fd66e1576fe70d892bfed719527 322 SUPERFAMILY SSF51735 5 313 2.9E-86 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS33370 0d427fd66e1576fe70d892bfed719527 322 Pfam PF01370 NAD dependent epimerase/dehydratase family 8 243 8.2E-52 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 SMALA_RS13025 fc0da14b99585fd51d97cea43cfd70ca 281 Gene3D G3DSA:3.40.50.10170 1 154 9.8E-48 T 29-03-2018 SMALA_RS13025 fc0da14b99585fd51d97cea43cfd70ca 281 Gene3D G3DSA:3.30.1180.10 155 281 2.6E-42 T 29-03-2018 SMALA_RS13025 fc0da14b99585fd51d97cea43cfd70ca 281 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 5 278 2.2E-87 T 29-03-2018 IPR003797 DegV SMALA_RS13025 fc0da14b99585fd51d97cea43cfd70ca 281 SUPERFAMILY SSF82549 5 280 3.66E-76 T 29-03-2018 SMALA_RS13025 fc0da14b99585fd51d97cea43cfd70ca 281 Pfam PF02645 Uncharacterised protein, DegV family COG1307 5 280 2.6E-85 T 29-03-2018 IPR003797 DegV SMALA_RS03470 41341d9f6b6ac67a94b6140c769ac3b9 510 Gene3D G3DSA:3.30.420.40 4 251 2.1E-90 T 29-03-2018 SMALA_RS03470 41341d9f6b6ac67a94b6140c769ac3b9 510 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 366 386 - T 29-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 SMALA_RS03470 41341d9f6b6ac67a94b6140c769ac3b9 510 PIRSF PIRSF000538 8 506 1.6E-164 T 29-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 SMALA_RS03470 41341d9f6b6ac67a94b6140c769ac3b9 510 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 10 255 8.1E-77 T 29-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 SMALA_RS03470 41341d9f6b6ac67a94b6140c769ac3b9 510 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 264 454 2.5E-63 T 29-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 SMALA_RS03470 41341d9f6b6ac67a94b6140c769ac3b9 510 SUPERFAMILY SSF53067 258 501 1.88E-80 T 29-03-2018 SMALA_RS03470 41341d9f6b6ac67a94b6140c769ac3b9 510 Hamap MF_00186 Glycerol kinase [glpK]. 6 501 54.715 T 29-03-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 SMALA_RS03470 41341d9f6b6ac67a94b6140c769ac3b9 510 SUPERFAMILY SSF53067 8 258 6.11E-92 T 29-03-2018 SMALA_RS03470 41341d9f6b6ac67a94b6140c769ac3b9 510 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 9 500 7.8E-217 T 29-03-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 SMALA_RS03470 41341d9f6b6ac67a94b6140c769ac3b9 510 Gene3D G3DSA:3.30.420.40 252 508 2.1E-78 T 29-03-2018 SMALA_RS15155 7a281a2d00274315eec78f96e34effa7 213 Gene3D G3DSA:3.30.450.40 73 150 1.4E-14 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS15155 7a281a2d00274315eec78f96e34effa7 213 Gene3D G3DSA:3.30.450.40 151 213 2.5E-7 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS15155 7a281a2d00274315eec78f96e34effa7 213 SUPERFAMILY SSF55781 67 212 4.91E-20 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS15155 7a281a2d00274315eec78f96e34effa7 213 Gene3D G3DSA:1.10.10.10 1 72 4.5E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS15155 7a281a2d00274315eec78f96e34effa7 213 SMART SM00346 6 93 5.1E-16 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMALA_RS15155 7a281a2d00274315eec78f96e34effa7 213 SUPERFAMILY SSF46785 7 76 3.42E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS15155 7a281a2d00274315eec78f96e34effa7 213 Pfam PF09339 IclR helix-turn-helix domain 8 58 2.9E-15 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMALA_RS23160 5f827ddacbf5dd36de90ff80d7bf605b 531 Gene3D G3DSA:3.30.300.30 429 529 5.8E-28 T 29-03-2018 SMALA_RS23160 5f827ddacbf5dd36de90ff80d7bf605b 531 Pfam PF13193 AMP-binding enzyme C-terminal domain 443 518 6.8E-21 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS23160 5f827ddacbf5dd36de90ff80d7bf605b 531 Pfam PF00501 AMP-binding enzyme 11 434 5.7E-96 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS23160 5f827ddacbf5dd36de90ff80d7bf605b 531 Gene3D G3DSA:2.30.38.10 354 428 1.6E-25 T 29-03-2018 SMALA_RS23160 5f827ddacbf5dd36de90ff80d7bf605b 531 Gene3D G3DSA:3.40.50.980 1 190 9.2E-41 T 29-03-2018 SMALA_RS23160 5f827ddacbf5dd36de90ff80d7bf605b 531 SUPERFAMILY SSF56801 2 526 1.09E-144 T 29-03-2018 SMALA_RS23160 5f827ddacbf5dd36de90ff80d7bf605b 531 Gene3D G3DSA:3.40.50.980 191 351 8.6E-45 T 29-03-2018 SMALA_RS23160 5f827ddacbf5dd36de90ff80d7bf605b 531 ProSitePatterns PS00455 Putative AMP-binding domain signature. 185 196 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS00870 a2d0a9c0a3176f7ef0577bd03c04a388 233 SMART SM01120 39 222 1.9E-46 T 29-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 SMALA_RS00870 a2d0a9c0a3176f7ef0577bd03c04a388 233 SUPERFAMILY SSF101473 10 219 1.44E-43 T 29-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 SMALA_RS00870 a2d0a9c0a3176f7ef0577bd03c04a388 233 Pfam PF02734 DAK2 domain 40 220 3.8E-41 T 29-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 SMALA_RS33175 e3d5e99698c343b17de45b2b20289362 224 Pfam PF00834 Ribulose-phosphate 3 epimerase family 5 199 6.8E-79 T 29-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 SMALA_RS33175 e3d5e99698c343b17de45b2b20289362 224 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 30 44 - T 29-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 SMALA_RS33175 e3d5e99698c343b17de45b2b20289362 224 PIRSF PIRSF001461 1 221 2.5E-96 T 29-03-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 SMALA_RS33175 e3d5e99698c343b17de45b2b20289362 224 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 132 154 - T 29-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 SMALA_RS33175 e3d5e99698c343b17de45b2b20289362 224 Gene3D G3DSA:3.20.20.70 1 215 4.3E-84 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS33175 e3d5e99698c343b17de45b2b20289362 224 SUPERFAMILY SSF51366 3 212 2.36E-65 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 SMALA_RS33175 e3d5e99698c343b17de45b2b20289362 224 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 5 212 5.1E-82 T 29-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 SMALA_RS15930 58f07e6485784a81a08335535d667aae 338 Pfam PF00535 Glycosyl transferase family 2 10 174 9.7E-23 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 SMALA_RS15930 58f07e6485784a81a08335535d667aae 338 SUPERFAMILY SSF53448 2 248 5.34E-45 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS15930 58f07e6485784a81a08335535d667aae 338 Gene3D G3DSA:3.90.550.10 1 249 2.0E-38 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS27055 02509cc374e7fe105268cf1c0e22eb5e 319 Gene3D G3DSA:3.40.50.300 45 253 1.2E-37 T 29-03-2018 SMALA_RS27055 02509cc374e7fe105268cf1c0e22eb5e 319 SUPERFAMILY SSF52540 3 312 6.83E-76 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS27055 02509cc374e7fe105268cf1c0e22eb5e 319 Pfam PF03308 ArgK protein 20 280 3.5E-97 T 29-03-2018 SMALA_RS27055 02509cc374e7fe105268cf1c0e22eb5e 319 Gene3D G3DSA:1.20.5.170 3 42 5.9E-6 T 29-03-2018 SMALA_RS27055 02509cc374e7fe105268cf1c0e22eb5e 319 TIGRFAM TIGR00750 lao: LAO/AO transport system ATPase 15 312 3.7E-104 T 29-03-2018 IPR005129 SIMIBI class G3E GTPase, ArgK/MeaB GO:0003924|GO:0005525 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMALA_RS29620 42c580a70e82195b08498eba6339e6cc 687 Gene3D G3DSA:1.25.10.20 252 687 2.0E-5 T 29-03-2018 SMALA_RS03900 f79b1acc7970fdd07db0010c1b976570 157 Gene3D G3DSA:3.30.530.20 10 157 1.0E-25 T 29-03-2018 IPR023393 START-like domain SMALA_RS03900 f79b1acc7970fdd07db0010c1b976570 157 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 21 154 1.1E-22 T 29-03-2018 IPR019587 Polyketide cyclase/dehydrase SMALA_RS03900 f79b1acc7970fdd07db0010c1b976570 157 SUPERFAMILY SSF55961 17 154 8.6E-26 T 29-03-2018 SMALA_RS42870 8a3722cf58bf1267db9bd818f91a94dd 247 SUPERFAMILY SSF52218 23 246 1.22E-28 T 29-03-2018 IPR029039 Flavoprotein-like domain SMALA_RS42870 8a3722cf58bf1267db9bd818f91a94dd 247 Gene3D G3DSA:3.40.50.360 9 223 3.0E-17 T 29-03-2018 IPR029039 Flavoprotein-like domain SMALA_RS42870 8a3722cf58bf1267db9bd818f91a94dd 247 Pfam PF03358 NADPH-dependent FMN reductase 33 173 2.6E-11 T 29-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 SMALA_RS05935 4eab749b9e07cd21bb0b6e031b816688 113 Gene3D G3DSA:3.40.50.720 1 67 1.3E-5 T 29-03-2018 SMALA_RS05935 4eab749b9e07cd21bb0b6e031b816688 113 SUPERFAMILY SSF51735 12 75 8.0E-8 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS05935 4eab749b9e07cd21bb0b6e031b816688 113 Gene3D G3DSA:1.10.1040.10 68 108 1.5E-4 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMALA_RS05935 4eab749b9e07cd21bb0b6e031b816688 113 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 14 70 1.6E-7 T 29-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 SMALA_RS05935 4eab749b9e07cd21bb0b6e031b816688 113 SUPERFAMILY SSF48179 80 111 1.59E-5 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMALA_RS08205 b7be870305b6075d47ddccb8ecb293f4 401 SUPERFAMILY SSF54373 177 277 1.77E-40 T 29-03-2018 SMALA_RS08205 b7be870305b6075d47ddccb8ecb293f4 401 Gene3D G3DSA:3.50.50.60 6 171 1.9E-14 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS08205 b7be870305b6075d47ddccb8ecb293f4 401 Gene3D G3DSA:3.30.9.10 313 389 3.9E-11 T 29-03-2018 SMALA_RS08205 b7be870305b6075d47ddccb8ecb293f4 401 Gene3D G3DSA:3.30.9.10 172 288 9.3E-49 T 29-03-2018 SMALA_RS08205 b7be870305b6075d47ddccb8ecb293f4 401 SUPERFAMILY SSF51905 5 174 6.74E-53 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS08205 b7be870305b6075d47ddccb8ecb293f4 401 SUPERFAMILY SSF51905 276 383 6.74E-53 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS08205 b7be870305b6075d47ddccb8ecb293f4 401 Pfam PF01494 FAD binding domain 6 345 4.4E-74 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 SMALA_RS08205 b7be870305b6075d47ddccb8ecb293f4 401 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 280 295 1.7E-26 T 29-03-2018 SMALA_RS08205 b7be870305b6075d47ddccb8ecb293f4 401 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 1.7E-26 T 29-03-2018 SMALA_RS08205 b7be870305b6075d47ddccb8ecb293f4 401 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 153 168 1.7E-26 T 29-03-2018 SMALA_RS08205 b7be870305b6075d47ddccb8ecb293f4 401 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 295 311 1.7E-26 T 29-03-2018 SMALA_RS33160 66d3d997f4acdd345871eb15c7f368fd 691 Gene3D G3DSA:3.40.50.300 348 622 1.4E-70 T 29-03-2018 SMALA_RS33160 66d3d997f4acdd345871eb15c7f368fd 691 SUPERFAMILY SSF90123 27 350 7.98E-73 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMALA_RS33160 66d3d997f4acdd345871eb15c7f368fd 691 Gene3D G3DSA:1.20.1560.10 10 347 2.3E-65 T 29-03-2018 SMALA_RS33160 66d3d997f4acdd345871eb15c7f368fd 691 ProSitePatterns PS00211 ABC transporters family signature. 518 532 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS33160 66d3d997f4acdd345871eb15c7f368fd 691 Pfam PF00664 ABC transporter transmembrane region 43 314 3.3E-41 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMALA_RS33160 66d3d997f4acdd345871eb15c7f368fd 691 SMART SM00382 406 592 6.8E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS33160 66d3d997f4acdd345871eb15c7f368fd 691 Pfam PF00005 ABC transporter 397 546 5.0E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS33160 66d3d997f4acdd345871eb15c7f368fd 691 SUPERFAMILY SSF52540 391 617 3.62E-80 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS21890 96c954498c5ff8921f4d570f7ebad226 397 Pfam PF01139 tRNA-splicing ligase RtcB 29 397 1.9E-130 T 29-03-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 SMALA_RS21890 96c954498c5ff8921f4d570f7ebad226 397 SUPERFAMILY SSF103365 10 397 2.75E-130 T 29-03-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 SMALA_RS32125 d513b4a76dabcc1f3967f106758f1c1e 388 PIRSF PIRSF004640 15 376 5.2E-145 T 29-03-2018 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 SMALA_RS32125 d513b4a76dabcc1f3967f106758f1c1e 388 SUPERFAMILY SSF56014 279 363 5.49E-11 T 29-03-2018 SMALA_RS32125 d513b4a76dabcc1f3967f106758f1c1e 388 Pfam PF04551 GcpE protein 26 365 4.3E-133 T 29-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 SMALA_RS32125 d513b4a76dabcc1f3967f106758f1c1e 388 Gene3D G3DSA:3.20.20.120 25 163 2.0E-16 T 29-03-2018 IPR029065 Enolase C-terminal domain-like SMALA_RS32125 d513b4a76dabcc1f3967f106758f1c1e 388 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 22 364 1.4E-127 T 29-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 SMALA_RS32125 d513b4a76dabcc1f3967f106758f1c1e 388 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 20 371 33.589 T 29-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 SMALA_RS32125 d513b4a76dabcc1f3967f106758f1c1e 388 SUPERFAMILY SSF51717 50 223 1.65E-9 T 29-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMALA_RS06980 818701a468d254bec769357167e4d31d 408 Pfam PF01979 Amidohydrolase family 50 404 8.9E-42 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 SMALA_RS06980 818701a468d254bec769357167e4d31d 408 SUPERFAMILY SSF51338 6 54 2.79E-18 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS06980 818701a468d254bec769357167e4d31d 408 SUPERFAMILY SSF51338 364 406 2.79E-18 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS06980 818701a468d254bec769357167e4d31d 408 Gene3D G3DSA:2.30.40.10 343 408 1.2E-12 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS06980 818701a468d254bec769357167e4d31d 408 SUPERFAMILY SSF51556 54 364 1.13E-77 T 29-03-2018 IPR032466 Metal-dependent hydrolase SMALA_RS06980 818701a468d254bec769357167e4d31d 408 Gene3D G3DSA:3.20.20.140 69 342 9.0E-35 T 29-03-2018 SMALA_RS06980 818701a468d254bec769357167e4d31d 408 Gene3D G3DSA:2.30.40.10 3 68 5.5E-14 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS21580 d1df24832ed564d9306253ff0ef911a8 296 Gene3D G3DSA:1.10.3100.10 8 163 6.3E-14 T 29-03-2018 IPR027910 YdiL-like domain SMALA_RS21580 d1df24832ed564d9306253ff0ef911a8 296 Pfam PF13560 Helix-turn-helix domain 13 68 1.6E-11 T 29-03-2018 SMALA_RS21580 d1df24832ed564d9306253ff0ef911a8 296 SMART SM00530 17 72 2.3E-8 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS21580 d1df24832ed564d9306253ff0ef911a8 296 SUPERFAMILY SSF47413 12 72 5.91E-10 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS17115 bbab79a4ae1141cf447a783b83b191f7 437 Pfam PF13458 Periplasmic binding protein 54 388 1.3E-24 T 29-03-2018 IPR028081 Leucine-binding protein domain SMALA_RS17115 bbab79a4ae1141cf447a783b83b191f7 437 SUPERFAMILY SSF53822 46 419 8.95E-23 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SMALA_RS17115 bbab79a4ae1141cf447a783b83b191f7 437 Gene3D G3DSA:3.40.50.2300 41 395 1.8E-24 T 29-03-2018 SMALA_RS35290 f2cf97aa3d57ffc2208c45524ad938e5 147 ProSitePatterns PS00234 Gas vesicles protein GVPa signature 1. 20 34 - T 29-03-2018 IPR018493 Gas vesicle protein GvpA, conserved site GO:0005198|GO:0012506 SMALA_RS35290 f2cf97aa3d57ffc2208c45524ad938e5 147 Pfam PF00741 Gas vesicle protein 19 57 2.9E-12 T 29-03-2018 IPR000638 Gas vesicle protein GvpA GO:0005198|GO:0012506 SMALA_RS35290 f2cf97aa3d57ffc2208c45524ad938e5 147 ProSitePatterns PS00669 Gas vesicles protein GVPa signature 2. 53 66 - T 29-03-2018 IPR018493 Gas vesicle protein GvpA, conserved site GO:0005198|GO:0012506 SMALA_RS35290 f2cf97aa3d57ffc2208c45524ad938e5 147 Hamap MF_00576 Gas vesicle structural protein [gvpA]. 8 98 24.417 T 29-03-2018 IPR000638 Gas vesicle protein GvpA GO:0005198|GO:0012506 SMALA_RS33450 70e403a382e9e465f3dc403d2c19584d 393 Gene3D G3DSA:3.90.1150.10 294 388 4.3E-20 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS33450 70e403a382e9e465f3dc403d2c19584d 393 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 230 243 - T 29-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 SMALA_RS33450 70e403a382e9e465f3dc403d2c19584d 393 Gene3D G3DSA:3.40.640.10 41 293 1.9E-62 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS33450 70e403a382e9e465f3dc403d2c19584d 393 Pfam PF00155 Aminotransferase class I and II 29 380 4.8E-61 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMALA_RS33450 70e403a382e9e465f3dc403d2c19584d 393 SUPERFAMILY SSF53383 1 384 3.03E-102 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS33450 70e403a382e9e465f3dc403d2c19584d 393 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 111 132 1.1E-11 T 29-03-2018 SMALA_RS33450 70e403a382e9e465f3dc403d2c19584d 393 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 193 216 1.1E-11 T 29-03-2018 SMALA_RS33450 70e403a382e9e465f3dc403d2c19584d 393 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 224 248 1.1E-11 T 29-03-2018 SMALA_RS33450 70e403a382e9e465f3dc403d2c19584d 393 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 157 181 1.1E-11 T 29-03-2018 SMALA_RS33450 70e403a382e9e465f3dc403d2c19584d 393 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 89 109 1.1E-11 T 29-03-2018 SMALA_RS14520 780cdbdaa852f57e65fceda5d915ad63 411 Pfam PF01494 FAD binding domain 6 353 6.1E-42 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 SMALA_RS14520 780cdbdaa852f57e65fceda5d915ad63 411 SUPERFAMILY SSF51905 6 178 5.13E-58 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS14520 780cdbdaa852f57e65fceda5d915ad63 411 SUPERFAMILY SSF51905 275 390 5.13E-58 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS14520 780cdbdaa852f57e65fceda5d915ad63 411 Gene3D G3DSA:3.50.50.60 2 399 3.1E-46 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS14520 780cdbdaa852f57e65fceda5d915ad63 411 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 288 303 1.0E-23 T 29-03-2018 SMALA_RS14520 780cdbdaa852f57e65fceda5d915ad63 411 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 157 172 1.0E-23 T 29-03-2018 SMALA_RS14520 780cdbdaa852f57e65fceda5d915ad63 411 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 8 30 1.0E-23 T 29-03-2018 SMALA_RS14520 780cdbdaa852f57e65fceda5d915ad63 411 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 303 319 1.0E-23 T 29-03-2018 SMALA_RS40510 d9df82ee9ed03be417361d66a1cd7ef7 886 Pfam PF02687 FtsX-like permease family 785 869 2.6E-7 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 SMALA_RS40510 d9df82ee9ed03be417361d66a1cd7ef7 886 Pfam PF12704 MacB-like periplasmic core domain 19 209 1.9E-10 T 29-03-2018 IPR025857 MacB-like periplasmic core domain SMALA_RS26600 dff2aa2dc6d424ec1c421f625edaa199 176 SMART SM00347 48 148 5.0E-17 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS26600 dff2aa2dc6d424ec1c421f625edaa199 176 Gene3D G3DSA:1.10.10.10 22 163 2.0E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS26600 dff2aa2dc6d424ec1c421f625edaa199 176 Pfam PF01047 MarR family 59 112 4.6E-12 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS26600 dff2aa2dc6d424ec1c421f625edaa199 176 SUPERFAMILY SSF46785 29 162 3.81E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS28530 47e566161b5c8d15ded6fc371163eb9b 93 Pfam PF06013 Proteins of 100 residues with WXG 2 84 3.1E-16 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like SMALA_RS28530 47e566161b5c8d15ded6fc371163eb9b 93 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 2 87 1.3E-16 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like SMALA_RS28530 47e566161b5c8d15ded6fc371163eb9b 93 SUPERFAMILY SSF140453 1 92 5.1E-17 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like SMALA_RS28530 47e566161b5c8d15ded6fc371163eb9b 93 Gene3D G3DSA:1.10.287.1060 1 93 1.2E-18 T 29-03-2018 SMALA_RS31895 42db8689851b6247f5baddf861553e47 498 Gene3D G3DSA:1.10.1740.10 2 64 2.1E-8 T 29-03-2018 SMALA_RS31895 42db8689851b6247f5baddf861553e47 498 Gene3D G3DSA:1.10.10.10 65 153 1.3E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS31895 42db8689851b6247f5baddf861553e47 498 SUPERFAMILY SSF88946 9 56 2.16E-7 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS31895 42db8689851b6247f5baddf861553e47 498 SUPERFAMILY SSF88659 88 146 1.72E-5 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS08060 3e43a01cef07d560c543139326393b45 244 SUPERFAMILY SSF56524 67 235 1.11E-50 T 29-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 SMALA_RS08060 3e43a01cef07d560c543139326393b45 244 Pfam PF00174 Oxidoreductase molybdopterin binding domain 75 221 1.8E-36 T 29-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 SMALA_RS08060 3e43a01cef07d560c543139326393b45 244 Gene3D G3DSA:3.90.420.10 60 234 8.0E-51 T 29-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 SMALA_RS38495 74584a29a46d4a05f429d94b53b602aa 418 Gene3D G3DSA:2.30.40.10 3 71 7.7E-14 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS38495 74584a29a46d4a05f429d94b53b602aa 418 SUPERFAMILY SSF51338 371 392 1.21E-11 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS38495 74584a29a46d4a05f429d94b53b602aa 418 SUPERFAMILY SSF51338 4 58 1.21E-11 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS38495 74584a29a46d4a05f429d94b53b602aa 418 Gene3D G3DSA:3.20.20.140 72 367 6.6E-32 T 29-03-2018 SMALA_RS38495 74584a29a46d4a05f429d94b53b602aa 418 Pfam PF01979 Amidohydrolase family 54 395 2.8E-15 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 SMALA_RS38495 74584a29a46d4a05f429d94b53b602aa 418 SUPERFAMILY SSF51556 57 369 5.87E-44 T 29-03-2018 IPR032466 Metal-dependent hydrolase SMALA_RS15000 ced3e927af05b87c6a26ad9511aef274 211 Gene3D G3DSA:3.90.950.10 1 209 1.9E-77 T 29-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like SMALA_RS15000 ced3e927af05b87c6a26ad9511aef274 211 Pfam PF01725 Ham1 family 15 203 2.5E-54 T 29-03-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 Reactome: R-HSA-74259 SMALA_RS15000 ced3e927af05b87c6a26ad9511aef274 211 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 15 202 1.9E-50 T 29-03-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 Reactome: R-HSA-74259 SMALA_RS15000 ced3e927af05b87c6a26ad9511aef274 211 SUPERFAMILY SSF52972 10 207 1.52E-64 T 29-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like SMALA_RS15000 ced3e927af05b87c6a26ad9511aef274 211 Hamap MF_01405 dITP/XTP pyrophosphatase [rdgB]. 13 208 46.499 T 29-03-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 SMALA_RS37910 d672cb545b4919071a42a3aa4deae72f 257 Pfam PF07729 FCD domain 118 233 4.1E-18 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS37910 d672cb545b4919071a42a3aa4deae72f 257 Pfam PF00392 Bacterial regulatory proteins, gntR family 28 85 1.8E-14 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS37910 d672cb545b4919071a42a3aa4deae72f 257 Gene3D G3DSA:1.20.120.530 109 251 3.8E-23 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS37910 d672cb545b4919071a42a3aa4deae72f 257 Gene3D G3DSA:1.10.10.10 18 93 2.9E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS37910 d672cb545b4919071a42a3aa4deae72f 257 SUPERFAMILY SSF46785 21 106 3.96E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS37910 d672cb545b4919071a42a3aa4deae72f 257 SUPERFAMILY SSF48008 112 237 2.88E-20 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS37910 d672cb545b4919071a42a3aa4deae72f 257 SMART SM00345 30 91 3.7E-10 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS37910 d672cb545b4919071a42a3aa4deae72f 257 SMART SM00895 115 234 1.8E-13 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS27675 f6b49d941c354368d757a4687680587a 496 Pfam PF07364 Metallopeptidase family M81 12 293 7.9E-106 T 29-03-2018 IPR015995 Microcystin LR degradation protein MlrC, N-terminal SMALA_RS27675 f6b49d941c354368d757a4687680587a 496 Pfam PF07171 MlrC C-terminus 303 473 6.3E-48 T 29-03-2018 IPR010799 Microcystin LR degradation protein MlrC, C-terminal SMALA_RS27675 f6b49d941c354368d757a4687680587a 496 PIRSF PIRSF012702 8 491 2.2E-139 T 29-03-2018 IPR009197 Microcystin LR degradation protein MlrC SMALA_RS28570 10062404930ffb0bed274e7db58258cc 1321 Gene3D G3DSA:3.40.50.300 1067 1269 4.6E-7 T 29-03-2018 SMALA_RS28570 10062404930ffb0bed274e7db58258cc 1321 Gene3D G3DSA:3.40.50.300 783 1014 5.9E-12 T 29-03-2018 SMALA_RS28570 10062404930ffb0bed274e7db58258cc 1321 Gene3D G3DSA:3.40.50.300 367 653 3.2E-18 T 29-03-2018 SMALA_RS28570 10062404930ffb0bed274e7db58258cc 1321 SUPERFAMILY SSF52540 430 656 3.42E-28 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS28570 10062404930ffb0bed274e7db58258cc 1321 SMART SM00382 466 645 0.77 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS28570 10062404930ffb0bed274e7db58258cc 1321 SMART SM00382 1111 1297 1.4 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS28570 10062404930ffb0bed274e7db58258cc 1321 SMART SM00382 824 1000 0.13 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS28570 10062404930ffb0bed274e7db58258cc 1321 SUPERFAMILY SSF52540 1062 1249 5.04E-10 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS28570 10062404930ffb0bed274e7db58258cc 1321 TIGRFAM TIGR03924 T7SS_EccC_a: type VII secretion protein EccCa 24 689 8.7E-258 T 29-03-2018 IPR023836 EccCa-like, Actinobacteria SMALA_RS28570 10062404930ffb0bed274e7db58258cc 1321 SUPERFAMILY SSF52540 787 1018 1.18E-18 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS28570 10062404930ffb0bed274e7db58258cc 1321 Pfam PF01580 FtsK/SpoIIIE family 438 557 3.2E-24 T 29-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 SMALA_RS28570 10062404930ffb0bed274e7db58258cc 1321 Pfam PF01580 FtsK/SpoIIIE family 805 1031 1.5E-44 T 29-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 SMALA_RS28570 10062404930ffb0bed274e7db58258cc 1321 TIGRFAM TIGR03925 T7SS_EccC_b: type VII secretion protein EccCb 743 1315 1.3E-229 T 29-03-2018 IPR023837 EccCb-like, Actinobacteria SMALA_RS13975 a78ed824eec8d3e5ee7cc12e09d09afd 302 SUPERFAMILY SSF46785 1 85 3.81E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS13975 a78ed824eec8d3e5ee7cc12e09d09afd 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.4E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS13975 a78ed824eec8d3e5ee7cc12e09d09afd 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.4E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS13975 a78ed824eec8d3e5ee7cc12e09d09afd 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.4E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS13975 a78ed824eec8d3e5ee7cc12e09d09afd 302 SUPERFAMILY SSF53850 88 288 7.06E-32 T 29-03-2018 SMALA_RS13975 a78ed824eec8d3e5ee7cc12e09d09afd 302 Gene3D G3DSA:3.40.190.10 177 260 4.5E-21 T 29-03-2018 SMALA_RS13975 a78ed824eec8d3e5ee7cc12e09d09afd 302 Gene3D G3DSA:1.10.10.10 1 88 4.9E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS13975 a78ed824eec8d3e5ee7cc12e09d09afd 302 Pfam PF03466 LysR substrate binding domain 87 288 2.1E-34 T 29-03-2018 IPR005119 LysR, substrate-binding SMALA_RS13975 a78ed824eec8d3e5ee7cc12e09d09afd 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.0E-21 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS13975 a78ed824eec8d3e5ee7cc12e09d09afd 302 Gene3D G3DSA:3.40.190.10 89 176 1.8E-17 T 29-03-2018 SMALA_RS01405 09e99e4c3ec6a63d3e11e39f5d273c8f 658 SUPERFAMILY SSF51445 176 480 1.47E-104 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS01405 09e99e4c3ec6a63d3e11e39f5d273c8f 658 SUPERFAMILY SSF55545 38 174 9.29E-17 T 29-03-2018 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMALA_RS01405 09e99e4c3ec6a63d3e11e39f5d273c8f 658 Pfam PF07555 beta-N-acetylglucosaminidase 179 477 1.2E-110 T 29-03-2018 IPR011496 Beta-N-acetylglucosaminidase MetaCyc: PWY-7437 SMALA_RS01405 09e99e4c3ec6a63d3e11e39f5d273c8f 658 Gene3D G3DSA:1.20.58.460 496 657 1.6E-33 T 29-03-2018 SMALA_RS01405 09e99e4c3ec6a63d3e11e39f5d273c8f 658 Gene3D G3DSA:3.30.379.10 25 173 9.9E-18 T 29-03-2018 SMALA_RS01405 09e99e4c3ec6a63d3e11e39f5d273c8f 658 SUPERFAMILY SSF140657 517 649 1.99E-5 T 29-03-2018 SMALA_RS01405 09e99e4c3ec6a63d3e11e39f5d273c8f 658 Gene3D G3DSA:3.20.20.80 176 495 3.2E-114 T 29-03-2018 SMALA_RS01405 09e99e4c3ec6a63d3e11e39f5d273c8f 658 Pfam PF02838 Glycosyl hydrolase family 20, domain 2 38 172 5.2E-20 T 29-03-2018 IPR015882 Beta-hexosaminidase, bacteial type, N-terminal KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822 SMALA_RS06990 ed5347189a5f7be9c574a9ca2c5891be 456 Gene3D G3DSA:1.10.45.10 413 452 3.9E-16 T 29-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 SMALA_RS06990 ed5347189a5f7be9c574a9ca2c5891be 456 SUPERFAMILY SSF55103 217 454 5.56E-58 T 29-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 SMALA_RS06990 ed5347189a5f7be9c574a9ca2c5891be 456 Pfam PF01565 FAD binding domain 39 176 4.3E-41 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 SMALA_RS06990 ed5347189a5f7be9c574a9ca2c5891be 456 SUPERFAMILY SSF56176 5 213 4.07E-66 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SMALA_RS06990 ed5347189a5f7be9c574a9ca2c5891be 456 Gene3D G3DSA:3.30.43.10 1 89 2.8E-19 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 SMALA_RS06990 ed5347189a5f7be9c574a9ca2c5891be 456 Gene3D G3DSA:3.30.465.10 90 234 8.0E-42 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SMALA_RS06990 ed5347189a5f7be9c574a9ca2c5891be 456 Pfam PF02913 FAD linked oxidases, C-terminal domain 213 452 1.2E-58 T 29-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 SMALA_RS08225 37f746659df63418ef1a0343ff7edccc 746 SUPERFAMILY SSF51905 2 63 7.77E-7 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS08225 37f746659df63418ef1a0343ff7edccc 746 SUPERFAMILY SSF51905 117 214 7.77E-7 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS08225 37f746659df63418ef1a0343ff7edccc 746 Gene3D G3DSA:3.50.50.60 2 190 1.3E-4 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS08225 37f746659df63418ef1a0343ff7edccc 746 Pfam PF13454 FAD-NAD(P)-binding 10 192 3.1E-43 T 29-03-2018 SMALA_RS15160 a0c53027d69f112d36d9a99adbac9b14 598 SUPERFAMILY SSF52540 22 182 1.4E-25 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS15160 a0c53027d69f112d36d9a99adbac9b14 598 Pfam PF04851 Type III restriction enzyme, res subunit 27 178 2.9E-13 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 SMALA_RS15160 a0c53027d69f112d36d9a99adbac9b14 598 Gene3D G3DSA:3.40.50.300 23 185 1.9E-20 T 29-03-2018 SMALA_RS15160 a0c53027d69f112d36d9a99adbac9b14 598 SUPERFAMILY SSF52540 267 390 1.03E-16 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS15160 a0c53027d69f112d36d9a99adbac9b14 598 SUPERFAMILY SSF52540 140 212 1.03E-16 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS15160 a0c53027d69f112d36d9a99adbac9b14 598 SMART SM00487 24 200 5.5E-17 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain SMALA_RS15160 a0c53027d69f112d36d9a99adbac9b14 598 Gene3D G3DSA:3.40.50.300 270 450 6.3E-9 T 29-03-2018 SMALA_RS40070 00edb9e8cac98c2f42daf2fc5cb6eb52 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 9.5E-29 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40070 00edb9e8cac98c2f42daf2fc5cb6eb52 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 9.5E-29 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40070 00edb9e8cac98c2f42daf2fc5cb6eb52 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 9.5E-29 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40070 00edb9e8cac98c2f42daf2fc5cb6eb52 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 9.5E-29 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40070 00edb9e8cac98c2f42daf2fc5cb6eb52 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 9.5E-29 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40070 00edb9e8cac98c2f42daf2fc5cb6eb52 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 9.5E-29 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40070 00edb9e8cac98c2f42daf2fc5cb6eb52 255 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 192 6.3E-4 T 29-03-2018 SMALA_RS40070 00edb9e8cac98c2f42daf2fc5cb6eb52 255 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 148 176 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMALA_RS40070 00edb9e8cac98c2f42daf2fc5cb6eb52 255 SUPERFAMILY SSF51735 8 253 1.07E-65 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS40070 00edb9e8cac98c2f42daf2fc5cb6eb52 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 252 1.4E-52 T 29-03-2018 SMALA_RS40070 00edb9e8cac98c2f42daf2fc5cb6eb52 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 86 97 4.8E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40070 00edb9e8cac98c2f42daf2fc5cb6eb52 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 4.8E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40070 00edb9e8cac98c2f42daf2fc5cb6eb52 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 161 180 4.8E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40070 00edb9e8cac98c2f42daf2fc5cb6eb52 255 Gene3D G3DSA:3.40.50.720 50 255 7.8E-54 T 29-03-2018 SMALA_RS40070 00edb9e8cac98c2f42daf2fc5cb6eb52 255 Gene3D G3DSA:3.40.50.720 2 49 4.2E-4 T 29-03-2018 SMALA_RS20015 516124151522fcda36a1317d9271e0c2 559 Gene3D G3DSA:3.30.200.20 2 108 8.8E-21 T 29-03-2018 SMALA_RS20015 516124151522fcda36a1317d9271e0c2 559 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 147 159 - T 29-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMALA_RS20015 516124151522fcda36a1317d9271e0c2 559 Gene3D G3DSA:1.10.510.10 109 299 9.0E-51 T 29-03-2018 SMALA_RS20015 516124151522fcda36a1317d9271e0c2 559 SMART SM00220 20 287 2.7E-64 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMALA_RS20015 516124151522fcda36a1317d9271e0c2 559 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 26 49 - T 29-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 SMALA_RS20015 516124151522fcda36a1317d9271e0c2 559 SUPERFAMILY SSF56112 13 283 4.45E-74 T 29-03-2018 IPR011009 Protein kinase-like domain SMALA_RS20015 516124151522fcda36a1317d9271e0c2 559 Pfam PF00069 Protein kinase domain 20 283 1.0E-49 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMALA_RS20015 516124151522fcda36a1317d9271e0c2 559 Pfam PF03793 PASTA domain 494 555 4.4E-5 T 29-03-2018 IPR005543 PASTA domain SMALA_RS29635 89f2f5727a02f8962e6ca3744d459366 334 PRINTS PR00102 Ornithine carbamoyltransferase signature 310 321 3.0E-31 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SMALA_RS29635 89f2f5727a02f8962e6ca3744d459366 334 PRINTS PR00102 Ornithine carbamoyltransferase signature 84 97 3.0E-31 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SMALA_RS29635 89f2f5727a02f8962e6ca3744d459366 334 PRINTS PR00102 Ornithine carbamoyltransferase signature 124 138 3.0E-31 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SMALA_RS29635 89f2f5727a02f8962e6ca3744d459366 334 PRINTS PR00102 Ornithine carbamoyltransferase signature 51 65 3.0E-31 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SMALA_RS29635 89f2f5727a02f8962e6ca3744d459366 334 PRINTS PR00102 Ornithine carbamoyltransferase signature 229 239 3.0E-31 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SMALA_RS29635 89f2f5727a02f8962e6ca3744d459366 334 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 8 148 4.9E-46 T 29-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 SMALA_RS29635 89f2f5727a02f8962e6ca3744d459366 334 SUPERFAMILY SSF53671 4 332 1.31E-94 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SMALA_RS29635 89f2f5727a02f8962e6ca3744d459366 334 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 7 332 81.337 T 29-03-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 SMALA_RS29635 89f2f5727a02f8962e6ca3744d459366 334 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 158 329 3.0E-48 T 29-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 SMALA_RS29635 89f2f5727a02f8962e6ca3744d459366 334 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 8 331 2.8E-120 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SMALA_RS29635 89f2f5727a02f8962e6ca3744d459366 334 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 53 60 - T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SMALA_RS29635 89f2f5727a02f8962e6ca3744d459366 334 Gene3D G3DSA:3.40.50.1370 148 318 4.1E-48 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SMALA_RS29635 89f2f5727a02f8962e6ca3744d459366 334 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 267 276 1.6E-24 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SMALA_RS29635 89f2f5727a02f8962e6ca3744d459366 334 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 135 146 1.6E-24 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SMALA_RS29635 89f2f5727a02f8962e6ca3744d459366 334 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 53 72 1.6E-24 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SMALA_RS29635 89f2f5727a02f8962e6ca3744d459366 334 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 296 319 1.6E-24 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SMALA_RS29635 89f2f5727a02f8962e6ca3744d459366 334 Gene3D G3DSA:3.40.50.1370 1 147 4.0E-54 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SMALA_RS39840 c4724881dc802c1b072b7eb4f83df444 727 Gene3D G3DSA:1.20.1640.10 487 705 2.9E-36 T 29-03-2018 SMALA_RS39840 c4724881dc802c1b072b7eb4f83df444 727 Gene3D G3DSA:1.20.1640.10 145 352 2.7E-32 T 29-03-2018 SMALA_RS39840 c4724881dc802c1b072b7eb4f83df444 727 Pfam PF03176 MMPL family 463 708 1.2E-39 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 SMALA_RS39840 c4724881dc802c1b072b7eb4f83df444 727 Pfam PF03176 MMPL family 68 387 4.2E-61 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 SMALA_RS39840 c4724881dc802c1b072b7eb4f83df444 727 SUPERFAMILY SSF82866 493 707 1.57E-30 T 29-03-2018 SMALA_RS39840 c4724881dc802c1b072b7eb4f83df444 727 SUPERFAMILY SSF82866 144 353 6.41E-36 T 29-03-2018 SMALA_RS09345 3c74d5babdb854ad3eea54f55e161066 223 Gene3D G3DSA:1.20.120.530 77 215 7.1E-26 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS09345 3c74d5babdb854ad3eea54f55e161066 223 SMART SM00895 83 202 7.9E-16 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS09345 3c74d5babdb854ad3eea54f55e161066 223 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 33 47 1.5E-5 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS09345 3c74d5babdb854ad3eea54f55e161066 223 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 63 1.5E-5 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS09345 3c74d5babdb854ad3eea54f55e161066 223 Gene3D G3DSA:1.10.10.10 2 76 2.6E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS09345 3c74d5babdb854ad3eea54f55e161066 223 Pfam PF07729 FCD domain 84 201 5.5E-23 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS09345 3c74d5babdb854ad3eea54f55e161066 223 SUPERFAMILY SSF46785 10 98 1.08E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS09345 3c74d5babdb854ad3eea54f55e161066 223 SUPERFAMILY SSF48008 83 206 2.62E-23 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS09345 3c74d5babdb854ad3eea54f55e161066 223 SMART SM00345 15 73 3.2E-15 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS09345 3c74d5babdb854ad3eea54f55e161066 223 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 73 1.3E-17 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS19345 1e007ed9b3800c5b4edbe5879d80f600 249 Gene3D G3DSA:1.20.5.1070 157 243 4.1E-6 T 29-03-2018 SMALA_RS15750 b0c4b10d46c1e7f62414273267d6fe63 239 Gene3D G3DSA:3.40.50.150 5 112 4.2E-9 T 29-03-2018 SMALA_RS15750 b0c4b10d46c1e7f62414273267d6fe63 239 SUPERFAMILY SSF53335 12 191 5.18E-10 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS37520 93fd47836a03147173381e9c76e7dae7 442 Hamap MF_02035 Hercynine oxygenase [egtB]. 1 441 53.257 T 29-03-2018 IPR032890 Hercynine oxygenase, Actinobacteria GO:0016491|GO:0052699 SMALA_RS37520 93fd47836a03147173381e9c76e7dae7 442 SUPERFAMILY SSF109854 21 149 1.04E-20 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes SMALA_RS37520 93fd47836a03147173381e9c76e7dae7 442 SUPERFAMILY SSF56436 181 441 4.33E-77 T 29-03-2018 IPR016187 C-type lectin fold SMALA_RS37520 93fd47836a03147173381e9c76e7dae7 442 TIGRFAM TIGR03440 egtB_TIGR03440: ergothioneine biosynthesis protein EgtB 21 438 5.8E-140 T 29-03-2018 IPR017806 Ergothioneine biosynthesis protein EgtB GO:0052699 SMALA_RS37520 93fd47836a03147173381e9c76e7dae7 442 Pfam PF03781 Sulfatase-modifying factor enzyme 1 180 439 1.8E-65 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 SMALA_RS37520 93fd47836a03147173381e9c76e7dae7 442 Pfam PF12867 DinB superfamily 22 153 5.1E-28 T 29-03-2018 IPR024775 DinB-like domain SMALA_RS37520 93fd47836a03147173381e9c76e7dae7 442 Gene3D G3DSA:1.20.120.450 4 166 2.3E-18 T 29-03-2018 SMALA_RS37520 93fd47836a03147173381e9c76e7dae7 442 Gene3D G3DSA:3.90.1580.10 174 442 1.9E-68 T 29-03-2018 SMALA_RS08170 4a3a09db0788d62bec3b707cf106312e 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 39 2.6E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS08170 4a3a09db0788d62bec3b707cf106312e 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 47 70 2.6E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS08170 4a3a09db0788d62bec3b707cf106312e 212 Gene3D G3DSA:1.10.10.60 21 66 1.5E-17 T 29-03-2018 SMALA_RS08170 4a3a09db0788d62bec3b707cf106312e 212 SUPERFAMILY SSF46689 20 98 1.39E-18 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS08170 4a3a09db0788d62bec3b707cf106312e 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 69 1.1E-16 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS08170 4a3a09db0788d62bec3b707cf106312e 212 Gene3D G3DSA:1.10.357.10 67 208 6.2E-20 T 29-03-2018 SMALA_RS08170 4a3a09db0788d62bec3b707cf106312e 212 SUPERFAMILY SSF48498 93 206 1.57E-16 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS26385 a5de435a16be8b64d3682e2099f7fd13 246 SMART SM00342 158 240 8.3E-11 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS26385 a5de435a16be8b64d3682e2099f7fd13 246 Gene3D G3DSA:1.10.10.60 196 242 2.8E-7 T 29-03-2018 SMALA_RS26385 a5de435a16be8b64d3682e2099f7fd13 246 Pfam PF12833 Helix-turn-helix domain 164 241 3.6E-14 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS26385 a5de435a16be8b64d3682e2099f7fd13 246 Gene3D G3DSA:1.10.10.60 106 195 2.4E-4 T 29-03-2018 SMALA_RS26385 a5de435a16be8b64d3682e2099f7fd13 246 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 195 236 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 SMALA_RS09260 087052c0134ffc582aac80dae722fa9f 348 Gene3D G3DSA:3.40.640.10 25 268 1.5E-29 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS09260 087052c0134ffc582aac80dae722fa9f 348 SUPERFAMILY SSF53383 11 346 2.33E-52 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS09260 087052c0134ffc582aac80dae722fa9f 348 Gene3D G3DSA:3.90.1150.10 269 348 1.1E-14 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS09260 087052c0134ffc582aac80dae722fa9f 348 Pfam PF00266 Aminotransferase class-V 15 342 1.4E-20 T 29-03-2018 IPR000192 Aminotransferase class V domain SMALA_RS25020 ba630b5b78d32ea9e4b041a66351f485 283 Gene3D G3DSA:3.10.129.10 161 283 1.3E-14 T 29-03-2018 SMALA_RS25020 ba630b5b78d32ea9e4b041a66351f485 283 Gene3D G3DSA:3.10.129.10 9 142 7.1E-13 T 29-03-2018 SMALA_RS25020 ba630b5b78d32ea9e4b041a66351f485 283 SUPERFAMILY SSF54637 159 264 2.77E-13 T 29-03-2018 IPR029069 HotDog domain SMALA_RS25020 ba630b5b78d32ea9e4b041a66351f485 283 SUPERFAMILY SSF54637 11 138 2.02E-11 T 29-03-2018 IPR029069 HotDog domain SMALA_RS13845 ef1e4b932605357d284842027dbd24a3 143 Gene3D G3DSA:1.10.287.1060 26 126 8.3E-8 T 29-03-2018 SMALA_RS31400 29b7cc66294d78aef2bd1b8f7c233921 292 SUPERFAMILY SSF51556 2 256 4.9E-52 T 29-03-2018 IPR032466 Metal-dependent hydrolase SMALA_RS31400 29b7cc66294d78aef2bd1b8f7c233921 292 PIRSF PIRSF005295 2 259 4.1E-101 T 29-03-2018 IPR012022 Protein of unknown function UCP005295 SMALA_RS31400 29b7cc66294d78aef2bd1b8f7c233921 292 Gene3D G3DSA:3.20.20.140 2 269 3.3E-44 T 29-03-2018 SMALA_RS31400 29b7cc66294d78aef2bd1b8f7c233921 292 Pfam PF01026 TatD related DNase 4 252 9.0E-13 T 29-03-2018 IPR001130 TatD family GO:0016788 SMALA_RS40080 42708468196d1f0d17efc01f12df126a 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 156 2.5E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40080 42708468196d1f0d17efc01f12df126a 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 189 206 2.5E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40080 42708468196d1f0d17efc01f12df126a 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 93 104 2.5E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40080 42708468196d1f0d17efc01f12df126a 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 2.5E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40080 42708468196d1f0d17efc01f12df126a 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 187 2.5E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40080 42708468196d1f0d17efc01f12df126a 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 223 243 2.5E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40080 42708468196d1f0d17efc01f12df126a 262 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 21 260 2.9E-66 T 29-03-2018 SMALA_RS40080 42708468196d1f0d17efc01f12df126a 262 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 155 183 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMALA_RS40080 42708468196d1f0d17efc01f12df126a 262 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 15 199 7.9E-5 T 29-03-2018 SMALA_RS40080 42708468196d1f0d17efc01f12df126a 262 SUPERFAMILY SSF51735 14 261 8.29E-80 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS40080 42708468196d1f0d17efc01f12df126a 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 154 2.8E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40080 42708468196d1f0d17efc01f12df126a 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 93 104 2.8E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40080 42708468196d1f0d17efc01f12df126a 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 168 187 2.8E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40080 42708468196d1f0d17efc01f12df126a 262 Gene3D G3DSA:3.40.50.720 57 262 1.6E-64 T 29-03-2018 SMALA_RS40080 42708468196d1f0d17efc01f12df126a 262 Gene3D G3DSA:3.40.50.720 12 56 1.7E-7 T 29-03-2018 SMALA_RS10020 151975d70016d697199cbb88d6b07f07 215 SUPERFAMILY SSF50475 52 210 2.06E-19 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS10020 151975d70016d697199cbb88d6b07f07 215 Gene3D G3DSA:2.30.110.10 56 209 1.0E-27 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS10020 151975d70016d697199cbb88d6b07f07 215 TIGRFAM TIGR04025 PPOX_FMN_DR2398: pyridoxamine 5'-phosphate oxidase, FMN-binding family 45 210 4.6E-62 T 29-03-2018 IPR024029 Pyridoxamine 5-phosphate oxidase, FMN-dependent SMALA_RS10020 151975d70016d697199cbb88d6b07f07 215 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 65 158 6.9E-16 T 29-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 SMALA_RS29560 55d68b770314a54f5d2036e0f079ed10 581 Gene3D G3DSA:2.160.10.10 386 510 1.2E-25 T 29-03-2018 SMALA_RS29560 55d68b770314a54f5d2036e0f079ed10 581 SUPERFAMILY SSF53448 28 290 5.18E-39 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS29560 55d68b770314a54f5d2036e0f079ed10 581 Pfam PF12804 MobA-like NTP transferase domain 30 161 4.7E-20 T 29-03-2018 IPR025877 MobA-like NTP transferase SMALA_RS29560 55d68b770314a54f5d2036e0f079ed10 581 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 27 525 30.383 T 29-03-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 SMALA_RS29560 55d68b770314a54f5d2036e0f079ed10 581 SUPERFAMILY SSF51161 295 390 7.79E-10 T 29-03-2018 IPR011004 Trimeric LpxA-like SMALA_RS29560 55d68b770314a54f5d2036e0f079ed10 581 SUPERFAMILY SSF51161 358 508 3.05E-28 T 29-03-2018 IPR011004 Trimeric LpxA-like SMALA_RS29560 55d68b770314a54f5d2036e0f079ed10 581 Gene3D G3DSA:3.90.550.10 18 278 3.6E-38 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS29560 55d68b770314a54f5d2036e0f079ed10 581 Gene3D G3DSA:2.160.10.10 279 385 1.8E-17 T 29-03-2018 SMALA_RS05350 da785f46fd6b03725fcaffd1e79c9e8b 338 Pfam PF00107 Zinc-binding dehydrogenase 176 289 2.7E-22 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMALA_RS05350 da785f46fd6b03725fcaffd1e79c9e8b 338 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 134 2.3E-27 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS05350 da785f46fd6b03725fcaffd1e79c9e8b 338 SMART SM00829 11 334 2.6E-9 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS05350 da785f46fd6b03725fcaffd1e79c9e8b 338 Gene3D G3DSA:3.40.50.20 183 334 9.3E-18 T 29-03-2018 SMALA_RS05350 da785f46fd6b03725fcaffd1e79c9e8b 338 Gene3D G3DSA:3.90.180.10 1 182 3.9E-54 T 29-03-2018 SMALA_RS05350 da785f46fd6b03725fcaffd1e79c9e8b 338 SUPERFAMILY SSF50129 6 161 1.1E-45 T 29-03-2018 IPR011032 GroES-like SMALA_RS05350 da785f46fd6b03725fcaffd1e79c9e8b 338 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 61 75 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 SMALA_RS05350 da785f46fd6b03725fcaffd1e79c9e8b 338 SUPERFAMILY SSF51735 140 304 4.34E-37 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS01210 829b65a584224b5f62fc7cb89e362761 312 TIGRFAM TIGR04187 GRASP_SAV_5884: ATP-grasp ribosomal peptide maturase, SAV_5884 family 2 304 2.3E-110 T 29-03-2018 IPR026449 ATP-grasp ribosomal peptide maturase, SAV_5884 family SMALA_RS01210 829b65a584224b5f62fc7cb89e362761 312 SUPERFAMILY SSF56059 128 304 3.39E-17 T 29-03-2018 SMALA_RS01210 829b65a584224b5f62fc7cb89e362761 312 Gene3D G3DSA:3.30.470.20 185 296 2.9E-12 T 29-03-2018 SMALA_RS01210 829b65a584224b5f62fc7cb89e362761 312 Gene3D G3DSA:3.30.470.20 124 169 0.092 T 29-03-2018 SMALA_RS01210 829b65a584224b5f62fc7cb89e362761 312 Gene3D G3DSA:3.40.50.20 1 123 0.001 T 29-03-2018 SMALA_RS06180 ae0bb6f6fc9a467aeb0827a416d1217e 407 Pfam PF01494 FAD binding domain 17 359 1.5E-15 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 SMALA_RS06180 ae0bb6f6fc9a467aeb0827a416d1217e 407 SUPERFAMILY SSF51905 17 182 1.09E-51 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS06180 ae0bb6f6fc9a467aeb0827a416d1217e 407 SUPERFAMILY SSF51905 282 387 1.09E-51 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS06180 ae0bb6f6fc9a467aeb0827a416d1217e 407 Gene3D G3DSA:3.50.50.60 12 386 3.2E-37 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS06180 ae0bb6f6fc9a467aeb0827a416d1217e 407 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 161 176 4.4E-9 T 29-03-2018 SMALA_RS06180 ae0bb6f6fc9a467aeb0827a416d1217e 407 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 295 310 4.4E-9 T 29-03-2018 SMALA_RS06180 ae0bb6f6fc9a467aeb0827a416d1217e 407 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 17 39 4.4E-9 T 29-03-2018 SMALA_RS35610 38ddbab8765cd2e864aefe03195bd480 406 Pfam PF13796 Putative sensor 29 190 1.8E-30 T 29-03-2018 IPR025828 Putative sensor domain SMALA_RS35610 38ddbab8765cd2e864aefe03195bd480 406 SUPERFAMILY SSF55874 302 404 1.31E-13 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS35610 38ddbab8765cd2e864aefe03195bd480 406 Gene3D G3DSA:3.30.565.10 283 406 9.4E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS35610 38ddbab8765cd2e864aefe03195bd480 406 Pfam PF07730 Histidine kinase 218 284 3.8E-13 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMALA_RS06015 72b451418d68e7d9e1f43d6542685b3e 483 Gene3D G3DSA:3.30.565.10 307 481 1.2E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS06015 72b451418d68e7d9e1f43d6542685b3e 483 Gene3D G3DSA:1.10.287.130 245 306 7.3E-14 T 29-03-2018 SMALA_RS06015 72b451418d68e7d9e1f43d6542685b3e 483 Pfam PF00672 HAMP domain 202 250 8.2E-7 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMALA_RS06015 72b451418d68e7d9e1f43d6542685b3e 483 SUPERFAMILY SSF158472 203 251 9.81E-6 T 29-03-2018 SMALA_RS06015 72b451418d68e7d9e1f43d6542685b3e 483 SUPERFAMILY SSF47384 239 319 2.94E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS06015 72b451418d68e7d9e1f43d6542685b3e 483 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 364 477 3.9E-23 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS06015 72b451418d68e7d9e1f43d6542685b3e 483 SMART SM00304 201 254 2.9E-6 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMALA_RS06015 72b451418d68e7d9e1f43d6542685b3e 483 SUPERFAMILY SSF55874 311 478 7.33E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS06015 72b451418d68e7d9e1f43d6542685b3e 483 SMART SM00388 255 320 2.7E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS06015 72b451418d68e7d9e1f43d6542685b3e 483 Pfam PF00512 His Kinase A (phospho-acceptor) domain 255 319 6.6E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS06015 72b451418d68e7d9e1f43d6542685b3e 483 Gene3D G3DSA:3.30.450.20 22 178 9.9E-4 T 29-03-2018 SMALA_RS06015 72b451418d68e7d9e1f43d6542685b3e 483 PRINTS PR00344 Bacterial sensor protein C-terminal signature 417 427 9.3E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS06015 72b451418d68e7d9e1f43d6542685b3e 483 PRINTS PR00344 Bacterial sensor protein C-terminal signature 434 452 9.3E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS06015 72b451418d68e7d9e1f43d6542685b3e 483 PRINTS PR00344 Bacterial sensor protein C-terminal signature 399 413 9.3E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS06015 72b451418d68e7d9e1f43d6542685b3e 483 SMART SM00387 364 480 1.4E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS16850 8b37e5f07ceb1c04d4e303c7af04b59f 130 Pfam PF11222 Protein of unknown function (DUF3017) 38 108 1.2E-22 T 29-03-2018 IPR021385 Protein of unknown function DUF3017 SMALA_RS09890 1526cb4a6cd09cd11b1213ef2c1f8f3a 128 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 10 120 4.9E-7 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMALA_RS09890 1526cb4a6cd09cd11b1213ef2c1f8f3a 128 Gene3D G3DSA:3.10.180.10 1 128 2.5E-26 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS09890 1526cb4a6cd09cd11b1213ef2c1f8f3a 128 SUPERFAMILY SSF54593 1 125 3.89E-24 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS01070 5c61d2bb2d57aa5cc81f2e1b71d9f6a3 229 SUPERFAMILY SSF46955 113 209 1.37E-18 T 29-03-2018 IPR009061 Putative DNA-binding domain SMALA_RS01070 5c61d2bb2d57aa5cc81f2e1b71d9f6a3 229 SMART SM00422 113 182 1.4E-11 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS01070 5c61d2bb2d57aa5cc81f2e1b71d9f6a3 229 SMART SM00422 1 61 0.042 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS01070 5c61d2bb2d57aa5cc81f2e1b71d9f6a3 229 Gene3D G3DSA:1.10.1660.10 111 167 8.4E-18 T 29-03-2018 SMALA_RS01070 5c61d2bb2d57aa5cc81f2e1b71d9f6a3 229 Gene3D G3DSA:1.10.1660.10 1 110 1.6E-10 T 29-03-2018 SMALA_RS01070 5c61d2bb2d57aa5cc81f2e1b71d9f6a3 229 Pfam PF00376 MerR family regulatory protein 1 30 9.0E-8 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS01070 5c61d2bb2d57aa5cc81f2e1b71d9f6a3 229 SUPERFAMILY SSF46955 2 103 2.33E-9 T 29-03-2018 IPR009061 Putative DNA-binding domain SMALA_RS01070 5c61d2bb2d57aa5cc81f2e1b71d9f6a3 229 Gene3D G3DSA:1.10.1660.10 168 228 0.0092 T 29-03-2018 SMALA_RS01070 5c61d2bb2d57aa5cc81f2e1b71d9f6a3 229 Pfam PF13411 MerR HTH family regulatory protein 114 181 5.9E-16 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS05345 6cde236d0943e549dec20b0b21f21ad1 194 SUPERFAMILY SSF48498 81 192 5.09E-22 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS05345 6cde236d0943e549dec20b0b21f21ad1 194 Gene3D G3DSA:1.10.10.60 1 61 1.5E-22 T 29-03-2018 SMALA_RS05345 6cde236d0943e549dec20b0b21f21ad1 194 Pfam PF16925 Bacterial transcriptional repressor C-terminal 80 191 9.0E-25 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS05345 6cde236d0943e549dec20b0b21f21ad1 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 2.0E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS05345 6cde236d0943e549dec20b0b21f21ad1 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 2.0E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS05345 6cde236d0943e549dec20b0b21f21ad1 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 61 1.1E-18 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS05345 6cde236d0943e549dec20b0b21f21ad1 194 Gene3D G3DSA:1.10.357.10 62 194 6.1E-23 T 29-03-2018 SMALA_RS05345 6cde236d0943e549dec20b0b21f21ad1 194 SUPERFAMILY SSF46689 2 66 1.8E-20 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS22045 83f145306fb71b125fbe51fbec98585b 364 Gene3D G3DSA:1.10.10.10 277 313 0.002 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS22045 83f145306fb71b125fbe51fbec98585b 364 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 340 356 1.9E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SMALA_RS22045 83f145306fb71b125fbe51fbec98585b 364 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 325 340 1.9E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SMALA_RS22045 83f145306fb71b125fbe51fbec98585b 364 SMART SM00342 273 356 5.8E-20 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS22045 83f145306fb71b125fbe51fbec98585b 364 SUPERFAMILY SSF46689 309 359 7.17E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS22045 83f145306fb71b125fbe51fbec98585b 364 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 24 215 1.2E-47 T 29-03-2018 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal SMALA_RS22045 83f145306fb71b125fbe51fbec98585b 364 Pfam PF12833 Helix-turn-helix domain 280 357 1.1E-17 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS22045 83f145306fb71b125fbe51fbec98585b 364 Gene3D G3DSA:1.10.10.60 314 363 2.4E-12 T 29-03-2018 SMALA_RS35865 b314cca5f54429ac58acf01d0aa352cc 440 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 242 358 2.3E-4 T 29-03-2018 SMALA_RS35865 b314cca5f54429ac58acf01d0aa352cc 440 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 11 198 2.5E-25 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMALA_RS35865 b314cca5f54429ac58acf01d0aa352cc 440 TIGRFAM TIGR02467 CbiE: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit 13 209 4.6E-53 T 29-03-2018 IPR012818 Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase GO:0008276|GO:0009236 SMALA_RS35865 b314cca5f54429ac58acf01d0aa352cc 440 TIGRFAM TIGR02469 CbiT: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit 239 360 2.0E-32 T 29-03-2018 IPR014008 Cobalamin biosynthesis, precorrin-6Y methyltransferase, CbiT subunit GO:0008276|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.196|MetaCyc: PWY-2201|MetaCyc: PWY-7377 SMALA_RS35865 b314cca5f54429ac58acf01d0aa352cc 440 SUPERFAMILY SSF53335 214 403 4.02E-29 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS35865 b314cca5f54429ac58acf01d0aa352cc 440 PIRSF PIRSF036428 7 410 1.2E-149 T 29-03-2018 IPR006365 Cobalamin (vitamin B12) biosynthesis CobL/Precorrin-6Y C(5,15)-methyltransferase GO:0008276|GO:0009236 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|KEGG: 00860+2.1.1.132|MetaCyc: PWY-2201|MetaCyc: PWY-3841 SMALA_RS35865 b314cca5f54429ac58acf01d0aa352cc 440 Gene3D G3DSA:3.40.50.150 233 409 7.3E-33 T 29-03-2018 SMALA_RS35865 b314cca5f54429ac58acf01d0aa352cc 440 SUPERFAMILY SSF53790 11 213 8.24E-43 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMALA_RS35865 b314cca5f54429ac58acf01d0aa352cc 440 Gene3D G3DSA:3.30.950.10 123 220 2.4E-29 T 29-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMALA_RS35865 b314cca5f54429ac58acf01d0aa352cc 440 Gene3D G3DSA:3.40.1010.10 10 122 3.2E-20 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMALA_RS22320 ee095c658ff19cc9c1edbf1e7815c663 130 PIRSF PIRSF028777 1 130 8.6E-50 T 29-03-2018 IPR031308 Uncharacterised conserved protein UCP028777 SMALA_RS22320 ee095c658ff19cc9c1edbf1e7815c663 130 Pfam PF03733 Inner membrane component domain 4 54 4.4E-17 T 29-03-2018 IPR005185 Inner membrane component domain SMALA_RS22320 ee095c658ff19cc9c1edbf1e7815c663 130 Pfam PF03733 Inner membrane component domain 68 117 5.9E-17 T 29-03-2018 IPR005185 Inner membrane component domain SMALA_RS13195 4caebe511be2a5a92decd3d7674c59b1 486 Gene3D G3DSA:3.90.1310.10 17 138 1.7E-15 T 29-03-2018 SMALA_RS13195 4caebe511be2a5a92decd3d7674c59b1 486 SUPERFAMILY SSF56601 136 483 2.39E-85 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMALA_RS13195 4caebe511be2a5a92decd3d7674c59b1 486 Pfam PF00905 Penicillin binding protein transpeptidase domain 153 478 5.8E-66 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 SMALA_RS13195 4caebe511be2a5a92decd3d7674c59b1 486 Gene3D G3DSA:3.40.710.10 139 486 8.0E-86 T 29-03-2018 SMALA_RS35095 dafc329ec7d8f68d249be5c5aefbf32b 213 Gene3D G3DSA:1.20.1260.10 58 205 6.1E-15 T 29-03-2018 IPR012347 Ferritin-related SMALA_RS35095 dafc329ec7d8f68d249be5c5aefbf32b 213 Pfam PF13628 Domain of unknown function (DUF4142) 69 203 2.6E-18 T 29-03-2018 IPR025419 Domain of unknown function DUF4142 SMALA_RS19915 41811080416be00aa99116fdad94e93f 180 SUPERFAMILY SSF117916 19 114 8.17E-20 T 29-03-2018 IPR034904 Fe-S cluster assembly domain SMALA_RS19915 41811080416be00aa99116fdad94e93f 180 TIGRFAM TIGR02159 PA_CoA_Oxy4: phenylacetate-CoA oxygenase, PaaJ subunit 31 179 3.7E-52 T 29-03-2018 IPR011883 Phenylacetate-CoA oxygenase, PaaJ subunit SMALA_RS19915 41811080416be00aa99116fdad94e93f 180 Pfam PF01883 Iron-sulfur cluster assembly protein 29 96 2.0E-11 T 29-03-2018 IPR002744 MIP18 family-like SMALA_RS19915 41811080416be00aa99116fdad94e93f 180 Gene3D G3DSA:3.30.300.130 17 116 4.7E-18 T 29-03-2018 IPR034904 Fe-S cluster assembly domain SMALA_RS34330 b8e54e386efff2fd8e8eb290939e6a23 459 Gene3D G3DSA:3.40.190.10 53 188 2.1E-16 T 29-03-2018 SMALA_RS34330 b8e54e386efff2fd8e8eb290939e6a23 459 Pfam PF13416 Bacterial extracellular solute-binding protein 79 354 5.6E-33 T 29-03-2018 SMALA_RS34330 b8e54e386efff2fd8e8eb290939e6a23 459 SUPERFAMILY SSF53850 41 356 3.32E-57 T 29-03-2018 SMALA_RS34330 b8e54e386efff2fd8e8eb290939e6a23 459 Gene3D G3DSA:3.40.190.10 189 357 1.2E-35 T 29-03-2018 SMALA_RS29140 ba7aa8d67585b67f9ea4d939bcac48a3 214 PIRSF PIRSF035805 1 205 1.2E-36 T 29-03-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 SMALA_RS29140 ba7aa8d67585b67f9ea4d939bcac48a3 214 SUPERFAMILY SSF52540 1 139 2.29E-27 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS29140 ba7aa8d67585b67f9ea4d939bcac48a3 214 Gene3D G3DSA:3.30.60.20 143 211 8.9E-22 T 29-03-2018 SMALA_RS29140 ba7aa8d67585b67f9ea4d939bcac48a3 214 Hamap MF_00124 Thymidine kinase [tdk]. 1 195 27.641 T 29-03-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 SMALA_RS29140 ba7aa8d67585b67f9ea4d939bcac48a3 214 SUPERFAMILY SSF57716 144 197 8.55E-9 T 29-03-2018 SMALA_RS29140 ba7aa8d67585b67f9ea4d939bcac48a3 214 Pfam PF00265 Thymidine kinase 4 192 1.1E-23 T 29-03-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 SMALA_RS29140 ba7aa8d67585b67f9ea4d939bcac48a3 214 Gene3D G3DSA:3.40.50.300 2 140 1.2E-33 T 29-03-2018 SMALA_RS21695 2a1b6d99242524d82b722160825ef818 209 SUPERFAMILY SSF46689 21 93 2.72E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS21695 2a1b6d99242524d82b722160825ef818 209 Gene3D G3DSA:1.10.357.10 81 209 8.3E-36 T 29-03-2018 SMALA_RS21695 2a1b6d99242524d82b722160825ef818 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 54 77 3.8E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS21695 2a1b6d99242524d82b722160825ef818 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 46 3.8E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS21695 2a1b6d99242524d82b722160825ef818 209 Gene3D G3DSA:1.10.10.60 7 78 1.9E-19 T 29-03-2018 SMALA_RS21695 2a1b6d99242524d82b722160825ef818 209 Pfam PF00440 Bacterial regulatory proteins, tetR family 33 79 1.4E-15 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS21695 2a1b6d99242524d82b722160825ef818 209 SUPERFAMILY SSF48498 99 208 1.27E-32 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS07020 0e8195a77b00271d7b4d7bedcbdd0cbb 535 Pfam PF07905 Purine catabolism regulatory protein-like family 10 129 1.2E-29 T 29-03-2018 IPR012914 Purine catabolism PurC-like domain SMALA_RS07020 0e8195a77b00271d7b4d7bedcbdd0cbb 535 Gene3D G3DSA:1.10.10.60 454 501 2.1E-9 T 29-03-2018 SMALA_RS07020 0e8195a77b00271d7b4d7bedcbdd0cbb 535 Pfam PF13556 PucR C-terminal helix-turn-helix domain 465 522 1.0E-17 T 29-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain SMALA_RS36830 326d1a5ad514f2cd8086898562293f29 122 Pfam PF03965 Penicillinase repressor 4 114 3.4E-27 T 29-03-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 SMALA_RS36830 326d1a5ad514f2cd8086898562293f29 122 SUPERFAMILY SSF46785 1 115 6.44E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS36830 326d1a5ad514f2cd8086898562293f29 122 PIRSF PIRSF019455 1 121 1.2E-20 T 29-03-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 SMALA_RS36830 326d1a5ad514f2cd8086898562293f29 122 Gene3D G3DSA:1.10.10.10 5 69 1.3E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS33400 a3b7fd9fafa5753dca5a5d0f2a023407 394 SUPERFAMILY SSF51569 10 295 2.56E-69 T 29-03-2018 SMALA_RS33400 a3b7fd9fafa5753dca5a5d0f2a023407 394 Pfam PF00682 HMGL-like 12 258 4.6E-63 T 29-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 SMALA_RS33400 a3b7fd9fafa5753dca5a5d0f2a023407 394 Gene3D G3DSA:3.20.20.70 1 337 5.2E-84 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS33400 a3b7fd9fafa5753dca5a5d0f2a023407 394 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 19 35 - T 29-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 SMALA_RS33400 a3b7fd9fafa5753dca5a5d0f2a023407 394 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 205 218 - T 29-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 SMALA_RS30560 20c320a21c6daf1da1b8b2f417675c78 385 TIGRFAM TIGR02961 allantoicase: allantoicase 34 362 2.6E-125 T 29-03-2018 IPR005164 Allantoicase GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697 SMALA_RS30560 20c320a21c6daf1da1b8b2f417675c78 385 Gene3D G3DSA:2.60.120.260 209 367 2.3E-50 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS30560 20c320a21c6daf1da1b8b2f417675c78 385 Gene3D G3DSA:2.60.120.260 17 207 1.1E-65 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS30560 20c320a21c6daf1da1b8b2f417675c78 385 PIRSF PIRSF016516 21 366 7.9E-96 T 29-03-2018 IPR005164 Allantoicase GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697 SMALA_RS30560 20c320a21c6daf1da1b8b2f417675c78 385 SUPERFAMILY SSF49785 25 206 7.65E-54 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS30560 20c320a21c6daf1da1b8b2f417675c78 385 Pfam PF03561 Allantoicase repeat 43 202 9.4E-46 T 29-03-2018 IPR015908 Allantoicase domain GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697 SMALA_RS30560 20c320a21c6daf1da1b8b2f417675c78 385 Pfam PF03561 Allantoicase repeat 225 362 3.7E-38 T 29-03-2018 IPR015908 Allantoicase domain GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697 SMALA_RS30560 20c320a21c6daf1da1b8b2f417675c78 385 SUPERFAMILY SSF49785 211 365 2.42E-43 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS30560 20c320a21c6daf1da1b8b2f417675c78 385 Hamap MF_00813 Probable allantoicase [alc]. 1 365 45.407 T 29-03-2018 IPR005164 Allantoicase GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697 SMALA_RS01330 30b2e347c705145ec6ce4a35de6891af 245 SUPERFAMILY SSF51735 2 234 6.04E-64 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS01330 30b2e347c705145ec6ce4a35de6891af 245 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMALA_RS01330 30b2e347c705145ec6ce4a35de6891af 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 7.3E-23 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS01330 30b2e347c705145ec6ce4a35de6891af 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 7.3E-23 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS01330 30b2e347c705145ec6ce4a35de6891af 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 7.3E-23 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS01330 30b2e347c705145ec6ce4a35de6891af 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 7.3E-23 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS01330 30b2e347c705145ec6ce4a35de6891af 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 7.3E-23 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS01330 30b2e347c705145ec6ce4a35de6891af 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 4.6E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS01330 30b2e347c705145ec6ce4a35de6891af 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 4.6E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS01330 30b2e347c705145ec6ce4a35de6891af 245 Gene3D G3DSA:3.40.50.720 2 244 1.7E-57 T 29-03-2018 SMALA_RS01330 30b2e347c705145ec6ce4a35de6891af 245 Pfam PF00106 short chain dehydrogenase 7 197 3.8E-50 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS39315 c76a04cf90b25bc10ea88fc39ccdc3b4 245 Gene3D G3DSA:3.40.50.720 47 240 9.9E-45 T 29-03-2018 SMALA_RS39315 c76a04cf90b25bc10ea88fc39ccdc3b4 245 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMALA_RS39315 c76a04cf90b25bc10ea88fc39ccdc3b4 245 SUPERFAMILY SSF51735 3 230 6.71E-62 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS39315 c76a04cf90b25bc10ea88fc39ccdc3b4 245 Gene3D G3DSA:3.40.50.10090 2 46 7.8E-11 T 29-03-2018 SMALA_RS39315 c76a04cf90b25bc10ea88fc39ccdc3b4 245 Pfam PF00106 short chain dehydrogenase 7 193 5.2E-52 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS39315 c76a04cf90b25bc10ea88fc39ccdc3b4 245 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 187 0.0025 T 29-03-2018 SMALA_RS39315 c76a04cf90b25bc10ea88fc39ccdc3b4 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 6.1E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS39315 c76a04cf90b25bc10ea88fc39ccdc3b4 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 6.1E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS39315 c76a04cf90b25bc10ea88fc39ccdc3b4 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 6.1E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS39315 c76a04cf90b25bc10ea88fc39ccdc3b4 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 6.1E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS39315 c76a04cf90b25bc10ea88fc39ccdc3b4 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 6.1E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS39315 c76a04cf90b25bc10ea88fc39ccdc3b4 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 1.3E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS39315 c76a04cf90b25bc10ea88fc39ccdc3b4 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 1.3E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS39315 c76a04cf90b25bc10ea88fc39ccdc3b4 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 1.3E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS34345 852f03d2aa993d4c5d8ecdf11a733d35 547 SUPERFAMILY SSF53743 19 156 1.83E-55 T 29-03-2018 IPR009015 L-fucose isomerase, N-terminal/central domain GO:0005737|GO:0005996|GO:0016861 SMALA_RS34345 852f03d2aa993d4c5d8ecdf11a733d35 547 SUPERFAMILY SSF53743 190 373 1.83E-55 T 29-03-2018 IPR009015 L-fucose isomerase, N-terminal/central domain GO:0005737|GO:0005996|GO:0016861 SMALA_RS34345 852f03d2aa993d4c5d8ecdf11a733d35 547 Gene3D G3DSA:3.40.50.1070 20 175 2.0E-33 T 29-03-2018 SMALA_RS34345 852f03d2aa993d4c5d8ecdf11a733d35 547 Gene3D G3DSA:3.40.275.10 210 348 4.0E-30 T 29-03-2018 SMALA_RS34345 852f03d2aa993d4c5d8ecdf11a733d35 547 Gene3D G3DSA:3.20.14.10 408 540 3.4E-26 T 29-03-2018 SMALA_RS09455 8a8d62977a658c00a3e1d8f87b5d4332 154 TIGRFAM TIGR01994 SUF_scaf_2: SUF system FeS assembly protein, NifU family 3 140 2.2E-48 T 29-03-2018 SMALA_RS09455 8a8d62977a658c00a3e1d8f87b5d4332 154 SUPERFAMILY SSF82649 2 143 2.25E-44 T 29-03-2018 SMALA_RS09455 8a8d62977a658c00a3e1d8f87b5d4332 154 Gene3D G3DSA:3.90.1010.10 1 142 1.1E-52 T 29-03-2018 SMALA_RS09455 8a8d62977a658c00a3e1d8f87b5d4332 154 Pfam PF01592 NifU-like N terminal domain 6 129 1.2E-27 T 29-03-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 SMALA_RS05685 9fb3527896d58dfb584edd20bedc9f76 334 Gene3D G3DSA:2.115.10.20 207 334 8.5E-9 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain SMALA_RS05685 9fb3527896d58dfb584edd20bedc9f76 334 Gene3D G3DSA:2.115.10.20 60 206 1.0E-18 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain SMALA_RS05685 9fb3527896d58dfb584edd20bedc9f76 334 SUPERFAMILY SSF75005 81 264 5.79E-16 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain SMALA_RS39510 91c5a5fb96de85c76942e51a36883395 279 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS39510 91c5a5fb96de85c76942e51a36883395 279 SMART SM00382 43 231 1.1E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS39510 91c5a5fb96de85c76942e51a36883395 279 Gene3D G3DSA:3.40.50.300 4 256 9.5E-62 T 29-03-2018 SMALA_RS39510 91c5a5fb96de85c76942e51a36883395 279 SUPERFAMILY SSF52540 19 243 9.38E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS39510 91c5a5fb96de85c76942e51a36883395 279 Pfam PF00005 ABC transporter 35 182 8.7E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS33080 7a3841c202ee12f3165e98605826f8ed 193 SUPERFAMILY SSF53271 12 180 3.54E-40 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like SMALA_RS33080 7a3841c202ee12f3165e98605826f8ed 193 Hamap MF_01219 Bifunctional protein PyrR [pyrR]. 9 184 36.972 T 29-03-2018 IPR023050 Bifunctional protein PyrR KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 SMALA_RS33080 7a3841c202ee12f3165e98605826f8ed 193 Pfam PF00156 Phosphoribosyl transferase domain 13 154 2.6E-19 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 SMALA_RS33080 7a3841c202ee12f3165e98605826f8ed 193 Gene3D G3DSA:3.40.50.2020 5 187 1.8E-35 T 29-03-2018 SMALA_RS23730 acdf0a0d7493d0c9a60211537f60b279 124 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 2 51 7.5E-19 T 29-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain SMALA_RS23730 acdf0a0d7493d0c9a60211537f60b279 124 SMART SM00834 2 41 1.0E-12 T 29-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain SMALA_RS23730 acdf0a0d7493d0c9a60211537f60b279 124 Pfam PF09723 Zinc ribbon domain 2 39 1.5E-12 T 29-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain SMALA_RS17735 6aac4b01e4daafd0589b83b097828b4d 261 SMART SM00866 101 251 2.0E-7 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMALA_RS17735 6aac4b01e4daafd0589b83b097828b4d 261 Gene3D G3DSA:1.10.10.10 1 67 9.1E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS17735 6aac4b01e4daafd0589b83b097828b4d 261 SUPERFAMILY SSF46785 2 70 2.38E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS17735 6aac4b01e4daafd0589b83b097828b4d 261 Pfam PF00392 Bacterial regulatory proteins, gntR family 3 66 1.4E-21 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS17735 6aac4b01e4daafd0589b83b097828b4d 261 SUPERFAMILY SSF64288 54 255 1.88E-21 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMALA_RS17735 6aac4b01e4daafd0589b83b097828b4d 261 Gene3D G3DSA:3.40.1410.10 68 254 4.9E-26 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMALA_RS17735 6aac4b01e4daafd0589b83b097828b4d 261 SMART SM00345 7 66 4.4E-21 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS17735 6aac4b01e4daafd0589b83b097828b4d 261 Pfam PF07702 UTRA domain 117 250 2.0E-12 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMALA_RS42755 671f0891875a0b6577c1106ab220a9c4 405 Pfam PF00155 Aminotransferase class I and II 77 378 5.2E-37 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMALA_RS42755 671f0891875a0b6577c1106ab220a9c4 405 Gene3D G3DSA:3.40.640.10 70 281 6.3E-44 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS42755 671f0891875a0b6577c1106ab220a9c4 405 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 242 255 - T 29-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 SMALA_RS42755 671f0891875a0b6577c1106ab220a9c4 405 Gene3D G3DSA:3.90.1150.10 282 396 9.3E-13 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS42755 671f0891875a0b6577c1106ab220a9c4 405 SUPERFAMILY SSF53383 70 393 3.16E-67 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS32135 3fe58831764ff5b4ab6a028d5ecda370 468 SUPERFAMILY SSF53383 40 444 1.65E-108 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS32135 3fe58831764ff5b4ab6a028d5ecda370 468 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 240 278 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMALA_RS32135 3fe58831764ff5b4ab6a028d5ecda370 468 Pfam PF00202 Aminotransferase class-III 49 442 1.9E-87 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMALA_RS32135 3fe58831764ff5b4ab6a028d5ecda370 468 Gene3D G3DSA:3.90.1150.10 16 194 3.6E-37 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS32135 3fe58831764ff5b4ab6a028d5ecda370 468 Gene3D G3DSA:3.90.1150.10 317 451 2.0E-24 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS32135 3fe58831764ff5b4ab6a028d5ecda370 468 Gene3D G3DSA:3.40.640.10 195 316 8.8E-37 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS32135 3fe58831764ff5b4ab6a028d5ecda370 468 PIRSF PIRSF000521 188 446 4.7E-28 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMALA_RS32135 3fe58831764ff5b4ab6a028d5ecda370 468 PIRSF PIRSF000521 145 181 29.0 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMALA_RS32135 3fe58831764ff5b4ab6a028d5ecda370 468 PIRSF PIRSF000521 24 149 9.1E-9 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMALA_RS41935 752b59488e4b438f645a9c3f50fc97b9 393 SUPERFAMILY SSF50022 17 161 2.23E-46 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMALA_RS41935 752b59488e4b438f645a9c3f50fc97b9 393 Pfam PF00355 Rieske [2Fe-2S] domain 50 133 1.4E-19 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMALA_RS41935 752b59488e4b438f645a9c3f50fc97b9 393 SUPERFAMILY SSF55961 164 391 2.12E-45 T 29-03-2018 SMALA_RS41935 752b59488e4b438f645a9c3f50fc97b9 393 Gene3D G3DSA:2.102.10.10 48 152 2.2E-29 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMALA_RS41935 752b59488e4b438f645a9c3f50fc97b9 393 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 146 172 2.9E-26 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 SMALA_RS41935 752b59488e4b438f645a9c3f50fc97b9 393 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 107 127 2.9E-26 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 SMALA_RS41935 752b59488e4b438f645a9c3f50fc97b9 393 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 184 206 2.9E-26 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 SMALA_RS41935 752b59488e4b438f645a9c3f50fc97b9 393 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 35 60 2.9E-26 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 SMALA_RS41935 752b59488e4b438f645a9c3f50fc97b9 393 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 65 80 2.9E-26 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 SMALA_RS41935 752b59488e4b438f645a9c3f50fc97b9 393 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 86 106 2.9E-26 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 SMALA_RS41935 752b59488e4b438f645a9c3f50fc97b9 393 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 185 389 1.3E-35 T 29-03-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 SMALA_RS41935 752b59488e4b438f645a9c3f50fc97b9 393 Gene3D G3DSA:3.90.380.10 153 385 1.3E-49 T 29-03-2018 SMALA_RS24980 1d3c4a68804ec3dfc9d416b7721a4eea 362 Gene3D G3DSA:3.10.20.30 262 361 6.2E-42 T 29-03-2018 IPR012675 Beta-grasp domain SMALA_RS24980 1d3c4a68804ec3dfc9d416b7721a4eea 362 Gene3D G3DSA:1.10.150.300 110 201 2.5E-22 T 29-03-2018 IPR023192 TGS-like domain Reactome: R-HSA-114608 SMALA_RS24980 1d3c4a68804ec3dfc9d416b7721a4eea 362 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 1.7E-34 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 SMALA_RS24980 1d3c4a68804ec3dfc9d416b7721a4eea 362 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 1.7E-34 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 SMALA_RS24980 1d3c4a68804ec3dfc9d416b7721a4eea 362 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 1.7E-34 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 SMALA_RS24980 1d3c4a68804ec3dfc9d416b7721a4eea 362 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 1.7E-34 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 SMALA_RS24980 1d3c4a68804ec3dfc9d416b7721a4eea 362 SUPERFAMILY SSF52540 3 300 5.93E-74 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS24980 1d3c4a68804ec3dfc9d416b7721a4eea 362 SUPERFAMILY SSF81271 278 362 2.05E-34 T 29-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 SMALA_RS24980 1d3c4a68804ec3dfc9d416b7721a4eea 362 Gene3D G3DSA:3.40.50.300 2 80 5.8E-9 T 29-03-2018 SMALA_RS24980 1d3c4a68804ec3dfc9d416b7721a4eea 362 Pfam PF01926 50S ribosome-binding GTPase 5 127 5.5E-23 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 SMALA_RS24980 1d3c4a68804ec3dfc9d416b7721a4eea 362 Pfam PF06071 Protein of unknown function (DUF933) 278 361 3.0E-38 T 29-03-2018 IPR013029 Domain of unknown function DUF933 Reactome: R-HSA-114608 SMALA_RS24980 1d3c4a68804ec3dfc9d416b7721a4eea 362 PIRSF PIRSF006641 1 362 1.2E-139 T 29-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 SMALA_RS24980 1d3c4a68804ec3dfc9d416b7721a4eea 362 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 3 362 6.0E-130 T 29-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 SMALA_RS24980 1d3c4a68804ec3dfc9d416b7721a4eea 362 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 362 42.162 T 29-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 SMALA_RS23415 369c7d8ec2c0c161ca44fceae8a3bd18 148 SUPERFAMILY SSF51182 30 102 2.09E-14 T 29-03-2018 IPR011051 RmlC-like cupin domain SMALA_RS23415 369c7d8ec2c0c161ca44fceae8a3bd18 148 Pfam PF07883 Cupin domain 45 101 1.2E-10 T 29-03-2018 IPR013096 Cupin 2, conserved barrel SMALA_RS23415 369c7d8ec2c0c161ca44fceae8a3bd18 148 Gene3D G3DSA:2.60.120.10 21 145 4.2E-17 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SMALA_RS26790 912565bd09b9a00e71ab1c2f4726b560 63 Pfam PF12728 Helix-turn-helix domain 6 58 1.5E-7 T 29-03-2018 SMALA_RS26790 912565bd09b9a00e71ab1c2f4726b560 63 Gene3D G3DSA:1.10.10.10 6 63 6.0E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS26790 912565bd09b9a00e71ab1c2f4726b560 63 SUPERFAMILY SSF46955 7 57 1.1E-6 T 29-03-2018 IPR009061 Putative DNA-binding domain SMALA_RS14650 7df54483f4e154156276e5981dbb36da 303 Pfam PF12146 Serine aminopeptidase, S33 72 189 3.1E-13 T 29-03-2018 IPR022742 Serine aminopeptidase, S33 SMALA_RS14650 7df54483f4e154156276e5981dbb36da 303 SUPERFAMILY SSF53474 7 302 2.13E-36 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS14650 7df54483f4e154156276e5981dbb36da 303 Gene3D G3DSA:3.40.50.1820 43 303 1.2E-33 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS15485 3ddcc4f8f63a70545361e5654919c410 110 TIGRFAM TIGR04186 GRASP_targ: putative ATP-grasp target RiPP 36 110 6.2E-28 T 29-03-2018 IPR026496 Putative ATP-grasp target RiPP SMALA_RS15485 3ddcc4f8f63a70545361e5654919c410 110 Pfam PF14408 Ribosomally synthesised peptide in actinomycetes 50 105 2.6E-19 T 29-03-2018 IPR025843 Ribosomally synthesized peptide in Actinomycetes SMALA_RS43075 37bcc5e81b59492182368517f4452d80 886 Gene3D G3DSA:3.40.50.300 279 511 1.6E-10 T 29-03-2018 SMALA_RS43075 37bcc5e81b59492182368517f4452d80 886 SUPERFAMILY SSF52540 267 324 3.58E-26 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS43075 37bcc5e81b59492182368517f4452d80 886 SUPERFAMILY SSF52540 36 213 3.58E-26 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS43075 37bcc5e81b59492182368517f4452d80 886 SUPERFAMILY SSF52540 366 453 3.58E-26 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS43075 37bcc5e81b59492182368517f4452d80 886 SMART SM00487 2 244 1.8E-9 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain SMALA_RS43075 37bcc5e81b59492182368517f4452d80 886 Pfam PF03457 Helicase associated domain 576 644 5.6E-11 T 29-03-2018 IPR005114 Helicase-associated SMALA_RS43075 37bcc5e81b59492182368517f4452d80 886 Pfam PF03457 Helicase associated domain 812 883 7.2E-7 T 29-03-2018 IPR005114 Helicase-associated SMALA_RS43075 37bcc5e81b59492182368517f4452d80 886 Pfam PF04851 Type III restriction enzyme, res subunit 31 211 4.2E-11 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 SMALA_RS43075 37bcc5e81b59492182368517f4452d80 886 Gene3D G3DSA:3.40.50.300 3 225 2.7E-17 T 29-03-2018 SMALA_RS21370 f17788917d3c837f9ab802e0df2e0f64 174 Pfam PF01661 Macro domain 20 137 4.8E-37 T 29-03-2018 IPR002589 Macro domain SMALA_RS21370 f17788917d3c837f9ab802e0df2e0f64 174 SUPERFAMILY SSF52949 3 171 9.08E-55 T 29-03-2018 SMALA_RS21370 f17788917d3c837f9ab802e0df2e0f64 174 SMART SM00506 3 137 1.9E-46 T 29-03-2018 IPR002589 Macro domain SMALA_RS21370 f17788917d3c837f9ab802e0df2e0f64 174 Gene3D G3DSA:3.40.220.10 1 174 1.7E-62 T 29-03-2018 SMALA_RS41035 cd4f23b6a946c017bc14677b596ccf1b 118 Gene3D G3DSA:1.10.10.10 1 66 3.7E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS41035 cd4f23b6a946c017bc14677b596ccf1b 118 SUPERFAMILY SSF46785 1 74 1.8E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS41035 cd4f23b6a946c017bc14677b596ccf1b 118 SMART SM00345 7 65 1.2E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS41035 cd4f23b6a946c017bc14677b596ccf1b 118 Pfam PF00392 Bacterial regulatory proteins, gntR family 4 65 8.5E-13 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS24150 a2981bf9f6195de1bd3cf48b9f7ae6c5 242 Pfam PF06386 Gas vesicle synthesis protein GvpL/GvpF 6 238 1.2E-57 T 29-03-2018 IPR009430 Gas vesicle protein GvpL/GvpF GO:0031411|GO:0031412 SMALA_RS37100 955318387fd79bc2a7395a1391c3cbba 129 Gene3D G3DSA:1.10.1660.10 56 128 3.4E-11 T 29-03-2018 SMALA_RS37100 955318387fd79bc2a7395a1391c3cbba 129 Gene3D G3DSA:1.10.1660.10 1 55 1.5E-18 T 29-03-2018 SMALA_RS37100 955318387fd79bc2a7395a1391c3cbba 129 Pfam PF13411 MerR HTH family regulatory protein 1 67 1.3E-16 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS37100 955318387fd79bc2a7395a1391c3cbba 129 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 3.9E-5 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS37100 955318387fd79bc2a7395a1391c3cbba 129 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 3.9E-5 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS37100 955318387fd79bc2a7395a1391c3cbba 129 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 3.9E-5 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS37100 955318387fd79bc2a7395a1391c3cbba 129 SMART SM00422 1 69 2.9E-17 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS37100 955318387fd79bc2a7395a1391c3cbba 129 SUPERFAMILY SSF46955 1 114 1.03E-24 T 29-03-2018 IPR009061 Putative DNA-binding domain SMALA_RS17495 6caa2656b0a4e6a76ae78c35db912599 313 Gene3D G3DSA:2.160.20.50 287 313 3.8E-4 T 29-03-2018 SMALA_RS17495 6caa2656b0a4e6a76ae78c35db912599 313 SUPERFAMILY SSF53697 2 242 4.25E-66 T 29-03-2018 SMALA_RS17495 6caa2656b0a4e6a76ae78c35db912599 313 Gene3D G3DSA:1.10.8.10 266 286 0.003 T 29-03-2018 SMALA_RS17495 6caa2656b0a4e6a76ae78c35db912599 313 Gene3D G3DSA:1.10.8.10 238 265 3.5E-6 T 29-03-2018 SMALA_RS17495 6caa2656b0a4e6a76ae78c35db912599 313 ProSitePatterns PS01272 Glucokinase regulatory protein family signature. 180 197 - T 29-03-2018 IPR005486 Glucokinase regulatory protein, conserved site KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126|Reactome: R-HSA-170822|Reactome: R-HSA-5619107 SMALA_RS17495 6caa2656b0a4e6a76ae78c35db912599 313 Gene3D G3DSA:3.40.50.10490 7 237 2.3E-52 T 29-03-2018 SMALA_RS17495 6caa2656b0a4e6a76ae78c35db912599 313 Hamap MF_00068 N-acetylmuramic acid 6-phosphate etherase [murQ]. 1 290 40.126 T 29-03-2018 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126 SMALA_RS17495 6caa2656b0a4e6a76ae78c35db912599 313 Pfam PF01380 SIS domain 122 202 9.4E-10 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 SMALA_RS17495 6caa2656b0a4e6a76ae78c35db912599 313 TIGRFAM TIGR00274 TIGR00274: N-acetylmuramic acid 6-phosphate etherase 1 291 1.4E-113 T 29-03-2018 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126 SMALA_RS18365 3a3b5428c1e13ae7150c19a89104e422 226 Pfam PF14016 Protein of unknown function (DUF4232) 88 219 8.0E-24 T 29-03-2018 IPR025326 Protein of unknown function DUF4232 SMALA_RS39245 66c786ac224d19305eb5ee0f728918bf 388 Gene3D G3DSA:3.75.10.10 1 388 1.6E-61 T 29-03-2018 SMALA_RS39245 66c786ac224d19305eb5ee0f728918bf 388 SUPERFAMILY SSF55909 3 387 6.96E-74 T 29-03-2018 SMALA_RS17385 d151a35435b10b47596ebfcba282360d 344 Pfam PF01032 FecCD transport family 30 339 5.2E-91 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 SMALA_RS17385 d151a35435b10b47596ebfcba282360d 344 SUPERFAMILY SSF81345 14 339 9.15E-81 T 29-03-2018 IPR029022 ABC transporter, BtuC-like SMALA_RS17385 d151a35435b10b47596ebfcba282360d 344 Gene3D G3DSA:1.10.3470.10 14 344 3.0E-71 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SMALA_RS38885 0c9d6023ee3a380386a1d72ef8ba4db1 172 Pfam PF00296 Luciferase-like monooxygenase 5 150 2.2E-9 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS38885 0c9d6023ee3a380386a1d72ef8ba4db1 172 SUPERFAMILY SSF51679 9 166 1.62E-14 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS38885 0c9d6023ee3a380386a1d72ef8ba4db1 172 Gene3D G3DSA:3.20.20.30 2 172 2.3E-14 T 29-03-2018 SMALA_RS07510 986312f9f1d7953ad4aabf900e0ec114 315 Gene3D G3DSA:1.10.357.10 183 299 1.3E-4 T 29-03-2018 SMALA_RS07510 986312f9f1d7953ad4aabf900e0ec114 315 Pfam PF12666 PrgI family protein 13 101 1.2E-15 T 29-03-2018 IPR024414 Uncharacterised protein family PrgI SMALA_RS23595 46d64498942e4ae5b81264731a75847a 532 SUPERFAMILY SSF53383 54 513 3.89E-123 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS23595 46d64498942e4ae5b81264731a75847a 532 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 101 120 6.8E-9 T 29-03-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 SMALA_RS23595 46d64498942e4ae5b81264731a75847a 532 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 378 393 6.8E-9 T 29-03-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 SMALA_RS23595 46d64498942e4ae5b81264731a75847a 532 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 421 440 6.8E-9 T 29-03-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 SMALA_RS23595 46d64498942e4ae5b81264731a75847a 532 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 141 160 6.8E-9 T 29-03-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 SMALA_RS23595 46d64498942e4ae5b81264731a75847a 532 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 99 439 2.3E-69 T 29-03-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 SMALA_RS23595 46d64498942e4ae5b81264731a75847a 532 Gene3D G3DSA:1.20.1650.10 19 99 1.5E-19 T 29-03-2018 SMALA_RS23595 46d64498942e4ae5b81264731a75847a 532 Gene3D G3DSA:3.40.640.10 111 392 4.9E-58 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS23595 46d64498942e4ae5b81264731a75847a 532 Gene3D G3DSA:3.90.1150.10 393 515 9.1E-25 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS20055 7cc4e3b7f713c916f160b65d0dde7c50 219 Gene3D G3DSA:1.20.120.530 72 218 1.4E-32 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS20055 7cc4e3b7f713c916f160b65d0dde7c50 219 Pfam PF07729 FCD domain 85 207 6.1E-23 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS20055 7cc4e3b7f713c916f160b65d0dde7c50 219 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 75 2.8E-17 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS20055 7cc4e3b7f713c916f160b65d0dde7c50 219 SUPERFAMILY SSF46785 8 79 3.5E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS20055 7cc4e3b7f713c916f160b65d0dde7c50 219 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 49 65 9.8E-9 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS20055 7cc4e3b7f713c916f160b65d0dde7c50 219 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 35 49 9.8E-9 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS20055 7cc4e3b7f713c916f160b65d0dde7c50 219 Gene3D G3DSA:1.10.10.10 1 71 3.1E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS20055 7cc4e3b7f713c916f160b65d0dde7c50 219 SMART SM00895 85 209 2.5E-16 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS20055 7cc4e3b7f713c916f160b65d0dde7c50 219 SMART SM00345 17 75 8.2E-13 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS20055 7cc4e3b7f713c916f160b65d0dde7c50 219 SUPERFAMILY SSF48008 81 212 5.49E-28 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS18940 972a7a41edf40c619c8f27e0681878a1 448 SUPERFAMILY SSF51735 203 447 2.78E-70 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS18940 972a7a41edf40c619c8f27e0681878a1 448 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 122 135 - T 29-03-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 SMALA_RS18940 972a7a41edf40c619c8f27e0681878a1 448 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 114 128 1.4E-29 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 SMALA_RS18940 972a7a41edf40c619c8f27e0681878a1 448 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 371 382 1.4E-29 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 SMALA_RS18940 972a7a41edf40c619c8f27e0681878a1 448 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 194 216 1.4E-29 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 SMALA_RS18940 972a7a41edf40c619c8f27e0681878a1 448 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 236 256 1.4E-29 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 SMALA_RS18940 972a7a41edf40c619c8f27e0681878a1 448 Gene3D G3DSA:3.40.50.10860 61 190 1.3E-54 T 29-03-2018 SMALA_RS18940 972a7a41edf40c619c8f27e0681878a1 448 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 203 446 6.0E-80 T 29-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 SMALA_RS18940 972a7a41edf40c619c8f27e0681878a1 448 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 57 185 4.2E-49 T 29-03-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 SMALA_RS18940 972a7a41edf40c619c8f27e0681878a1 448 Gene3D G3DSA:3.40.50.720 203 447 6.0E-66 T 29-03-2018 SMALA_RS18940 972a7a41edf40c619c8f27e0681878a1 448 PIRSF PIRSF000185 22 448 8.5E-116 T 29-03-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 SMALA_RS18940 972a7a41edf40c619c8f27e0681878a1 448 SUPERFAMILY SSF53223 7 197 3.84E-74 T 29-03-2018 SMALA_RS18940 972a7a41edf40c619c8f27e0681878a1 448 Gene3D G3DSA:1.10.285.10 6 60 5.8E-7 T 29-03-2018 SMALA_RS18940 972a7a41edf40c619c8f27e0681878a1 448 SMART SM00839 205 446 3.7E-81 T 29-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 SMALA_RS32345 254beb7e8570fc88174aec1344fba782 214 Pfam PF03458 UPF0126 domain 92 165 3.4E-19 T 29-03-2018 IPR005115 Uncharacterised domain UPF0126 SMALA_RS32345 254beb7e8570fc88174aec1344fba782 214 Pfam PF03458 UPF0126 domain 5 81 3.3E-21 T 29-03-2018 IPR005115 Uncharacterised domain UPF0126 SMALA_RS04265 3cfa77248c4797df60b710502fb94382 105 SUPERFAMILY SSF46785 5 96 1.54E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS04265 3cfa77248c4797df60b710502fb94382 105 Gene3D G3DSA:1.10.10.10 3 94 3.4E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS04265 3cfa77248c4797df60b710502fb94382 105 Pfam PF13601 Winged helix DNA-binding domain 15 93 2.8E-23 T 29-03-2018 IPR027395 Winged helix DNA-binding domain SMALA_RS04265 3cfa77248c4797df60b710502fb94382 105 SMART SM00347 4 101 0.0031 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS40045 b1d16aeb116813bc719aa18e23d4ff5f 409 Gene3D G3DSA:3.40.640.10 54 281 1.1E-45 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS40045 b1d16aeb116813bc719aa18e23d4ff5f 409 Gene3D G3DSA:3.90.1150.10 282 409 2.6E-31 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS40045 b1d16aeb116813bc719aa18e23d4ff5f 409 SUPERFAMILY SSF53383 13 402 6.46E-106 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS40045 b1d16aeb116813bc719aa18e23d4ff5f 409 Pfam PF00155 Aminotransferase class I and II 40 398 1.4E-68 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMALA_RS40045 b1d16aeb116813bc719aa18e23d4ff5f 409 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 244 257 - T 29-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 SMALA_RS15085 5be66f72ddca084a5a8f5676f3d4a50f 795 PIRSF PIRSF007519 3 794 1.8E-219 T 29-03-2018 IPR012300 Peptidase M6, InhA SMALA_RS15085 5be66f72ddca084a5a8f5676f3d4a50f 795 Pfam PF05547 Immune inhibitor A peptidase M6 96 786 4.1E-225 T 29-03-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 SMALA_RS15085 5be66f72ddca084a5a8f5676f3d4a50f 795 TIGRFAM TIGR03296 M6dom_TIGR03296: M6 family metalloprotease domain 163 469 2.2E-83 T 29-03-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 SMALA_RS15085 5be66f72ddca084a5a8f5676f3d4a50f 795 Gene3D G3DSA:3.40.390.10 61 419 1.3E-8 T 29-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 SMALA_RS15085 5be66f72ddca084a5a8f5676f3d4a50f 795 SUPERFAMILY SSF55486 338 417 3.91E-17 T 29-03-2018 SMALA_RS15085 5be66f72ddca084a5a8f5676f3d4a50f 795 SUPERFAMILY SSF55486 225 284 3.91E-17 T 29-03-2018 SMALA_RS15085 5be66f72ddca084a5a8f5676f3d4a50f 795 Gene3D G3DSA:2.60.120.260 420 593 8.2E-22 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS17500 a631d6520b60e9869b812c693ea7a931 541 Gene3D G3DSA:3.50.7.10 183 370 1.4E-96 T 29-03-2018 IPR027409 GroEL-like apical domain SMALA_RS17500 a631d6520b60e9869b812c693ea7a931 541 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 524 3.6E-251 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 SMALA_RS17500 a631d6520b60e9869b812c693ea7a931 541 Gene3D G3DSA:1.10.560.10 371 513 6.4E-25 T 29-03-2018 IPR027413 GroEL-like equatorial domain SMALA_RS17500 a631d6520b60e9869b812c693ea7a931 541 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 522 5.0E-97 T 29-03-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 SMALA_RS17500 a631d6520b60e9869b812c693ea7a931 541 SUPERFAMILY SSF52029 184 374 7.18E-84 T 29-03-2018 IPR027409 GroEL-like apical domain SMALA_RS17500 a631d6520b60e9869b812c693ea7a931 541 Gene3D G3DSA:1.10.560.10 2 182 9.9E-31 T 29-03-2018 IPR027413 GroEL-like equatorial domain SMALA_RS17500 a631d6520b60e9869b812c693ea7a931 541 SUPERFAMILY SSF54849 137 201 9.16E-27 T 29-03-2018 SMALA_RS17500 a631d6520b60e9869b812c693ea7a931 541 SUPERFAMILY SSF48592 6 133 9.16E-75 T 29-03-2018 SMALA_RS17500 a631d6520b60e9869b812c693ea7a931 541 SUPERFAMILY SSF48592 404 518 9.16E-75 T 29-03-2018 SMALA_RS17500 a631d6520b60e9869b812c693ea7a931 541 PRINTS PR00298 60kDa chaperonin signature 26 52 3.8E-70 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 SMALA_RS17500 a631d6520b60e9869b812c693ea7a931 541 PRINTS PR00298 60kDa chaperonin signature 82 109 3.8E-70 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 SMALA_RS17500 a631d6520b60e9869b812c693ea7a931 541 PRINTS PR00298 60kDa chaperonin signature 266 289 3.8E-70 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 SMALA_RS17500 a631d6520b60e9869b812c693ea7a931 541 PRINTS PR00298 60kDa chaperonin signature 348 373 3.8E-70 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 SMALA_RS17500 a631d6520b60e9869b812c693ea7a931 541 PRINTS PR00298 60kDa chaperonin signature 396 417 3.8E-70 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 SMALA_RS17500 a631d6520b60e9869b812c693ea7a931 541 ProSitePatterns PS00296 Chaperonins cpn60 signature. 403 414 - T 29-03-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 SMALA_RS17500 a631d6520b60e9869b812c693ea7a931 541 Hamap MF_00600 60 kDa chaperonin [groL]. 1 539 41.781 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 SMALA_RS28150 878f327748f917ea6afc8615b87df89f 276 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 276 100.869 T 29-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 SMALA_RS28150 878f327748f917ea6afc8615b87df89f 276 SUPERFAMILY SSF75217 1 245 1.31E-82 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases SMALA_RS28150 878f327748f917ea6afc8615b87df89f 276 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 22 232 1.3E-68 T 29-03-2018 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 SMALA_RS28150 878f327748f917ea6afc8615b87df89f 276 Gene3D G3DSA:1.10.1270.20 178 260 3.6E-27 T 29-03-2018 SMALA_RS28150 878f327748f917ea6afc8615b87df89f 276 Gene3D G3DSA:3.40.1280.10 1 177 7.4E-68 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal SMALA_RS28150 878f327748f917ea6afc8615b87df89f 276 PIRSF PIRSF000386 1 259 2.1E-93 T 29-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 SMALA_RS28150 878f327748f917ea6afc8615b87df89f 276 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 239 5.8E-65 T 29-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 SMALA_RS24935 02db7263b6e1b3099a789018a5a0dbb0 118 Pfam PF02467 Transcription factor WhiB 27 95 1.2E-21 T 29-03-2018 IPR034768 WhiB-like iron-sulfur binding domain SMALA_RS24935 02db7263b6e1b3099a789018a5a0dbb0 118 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 9 103 18.464 T 29-03-2018 IPR003482 Transcription factor WhiB SMALA_RS17840 d47e926d62abc3382df4cae72a03a29e 465 Pfam PF00392 Bacterial regulatory proteins, gntR family 32 93 5.6E-12 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS17840 d47e926d62abc3382df4cae72a03a29e 465 Gene3D G3DSA:1.10.10.10 21 95 1.7E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS17840 d47e926d62abc3382df4cae72a03a29e 465 Pfam PF00155 Aminotransferase class I and II 130 440 1.7E-15 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMALA_RS17840 d47e926d62abc3382df4cae72a03a29e 465 Gene3D G3DSA:3.40.640.10 138 343 7.7E-25 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS17840 d47e926d62abc3382df4cae72a03a29e 465 SMART SM00345 34 93 9.4E-11 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS17840 d47e926d62abc3382df4cae72a03a29e 465 SUPERFAMILY SSF46785 32 102 8.66E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS17840 d47e926d62abc3382df4cae72a03a29e 465 SUPERFAMILY SSF53383 113 450 4.27E-51 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS17840 d47e926d62abc3382df4cae72a03a29e 465 Gene3D G3DSA:3.90.1150.10 344 460 1.3E-12 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS28995 e4e9cd30e03b3358ffa22f6435e8600b 297 SUPERFAMILY SSF101478 4 288 1.7E-55 T 29-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 SMALA_RS28995 e4e9cd30e03b3358ffa22f6435e8600b 297 Gene3D G3DSA:1.10.4080.10 3 292 6.2E-65 T 29-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 SMALA_RS28995 e4e9cd30e03b3358ffa22f6435e8600b 297 Pfam PF03747 ADP-ribosylglycohydrolase 13 271 2.2E-49 T 29-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 SMALA_RS39170 fb824ffb701da6212beb34d1ba5f3e80 435 Gene3D G3DSA:3.40.640.10 69 329 8.4E-37 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS39170 fb824ffb701da6212beb34d1ba5f3e80 435 SUPERFAMILY SSF53383 34 431 4.13E-70 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS39170 fb824ffb701da6212beb34d1ba5f3e80 435 Pfam PF00155 Aminotransferase class I and II 81 425 9.3E-23 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMALA_RS39170 fb824ffb701da6212beb34d1ba5f3e80 435 Gene3D G3DSA:3.90.1150.10 330 433 4.7E-24 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS25800 d91aefd519c3ed6fab44b770ae0830e2 268 SUPERFAMILY SSF52096 2 267 2.49E-74 T 29-03-2018 IPR029045 ClpP/crotonase-like domain SMALA_RS25800 d91aefd519c3ed6fab44b770ae0830e2 268 Gene3D G3DSA:1.10.12.10 227 268 5.3E-12 T 29-03-2018 IPR014748 Crontonase, C-terminal SMALA_RS25800 d91aefd519c3ed6fab44b770ae0830e2 268 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 266 6.3E-56 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 SMALA_RS25800 d91aefd519c3ed6fab44b770ae0830e2 268 Gene3D G3DSA:3.90.226.10 4 226 1.4E-58 T 29-03-2018 SMALA_RS39615 1debfd103921e47345fedd27fbe06369 428 Gene3D G3DSA:1.20.1250.20 11 217 1.4E-25 T 29-03-2018 SMALA_RS39615 1debfd103921e47345fedd27fbe06369 428 Pfam PF07690 Major Facilitator Superfamily 32 365 3.8E-37 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS39615 1debfd103921e47345fedd27fbe06369 428 SUPERFAMILY SSF103473 16 403 1.31E-60 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS39615 1debfd103921e47345fedd27fbe06369 428 Gene3D G3DSA:1.20.1250.20 218 420 1.7E-25 T 29-03-2018 SMALA_RS06730 64fb7286589f6243f611e9c6f0621ca7 465 Pfam PF00501 AMP-binding enzyme 4 154 2.3E-29 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS06730 64fb7286589f6243f611e9c6f0621ca7 465 SMART SM00823 Phosphopantetheine attachment site 267 336 0.0023 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS06730 64fb7286589f6243f611e9c6f0621ca7 465 Gene3D G3DSA:2.30.38.10 64 148 1.4E-19 T 29-03-2018 SMALA_RS06730 64fb7286589f6243f611e9c6f0621ca7 465 SUPERFAMILY SSF56801 4 280 6.02E-62 T 29-03-2018 SMALA_RS06730 64fb7286589f6243f611e9c6f0621ca7 465 Gene3D G3DSA:1.10.1200.10 271 344 4.3E-20 T 29-03-2018 SMALA_RS06730 64fb7286589f6243f611e9c6f0621ca7 465 ProSitePatterns PS00012 Phosphopantetheine attachment site. 291 306 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS06730 64fb7286589f6243f611e9c6f0621ca7 465 Gene3D G3DSA:3.30.300.30 150 270 8.0E-25 T 29-03-2018 SMALA_RS06730 64fb7286589f6243f611e9c6f0621ca7 465 Gene3D G3DSA:3.40.50.980 2 60 2.7E-6 T 29-03-2018 SMALA_RS06730 64fb7286589f6243f611e9c6f0621ca7 465 Pfam PF00550 Phosphopantetheine attachment site 269 332 3.7E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS06730 64fb7286589f6243f611e9c6f0621ca7 465 SUPERFAMILY SSF47336 261 332 1.1E-18 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS20045 bb4765814cc13b1af6e7ab92c7ec5d3b 326 SMART SM00861 6 181 1.1E-69 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain SMALA_RS20045 bb4765814cc13b1af6e7ab92c7ec5d3b 326 Pfam PF02780 Transketolase, C-terminal domain 197 315 2.4E-37 T 29-03-2018 IPR033248 Transketolase, C-terminal domain SMALA_RS20045 bb4765814cc13b1af6e7ab92c7ec5d3b 326 SUPERFAMILY SSF52922 193 324 4.97E-37 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMALA_RS20045 bb4765814cc13b1af6e7ab92c7ec5d3b 326 Pfam PF02779 Transketolase, pyrimidine binding domain 5 180 1.2E-46 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain SMALA_RS20045 bb4765814cc13b1af6e7ab92c7ec5d3b 326 Gene3D G3DSA:3.40.50.920 196 325 3.9E-32 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMALA_RS20045 bb4765814cc13b1af6e7ab92c7ec5d3b 326 Gene3D G3DSA:3.40.50.970 2 195 3.4E-61 T 29-03-2018 SMALA_RS20045 bb4765814cc13b1af6e7ab92c7ec5d3b 326 SUPERFAMILY SSF52518 5 184 1.52E-67 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold SMALA_RS10895 6278575ac0e52f4f9b788c57b1b00e5f 315 Gene3D G3DSA:3.40.50.1000 47 315 6.3E-34 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS10895 6278575ac0e52f4f9b788c57b1b00e5f 315 SUPERFAMILY SSF56784 53 312 1.3E-52 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS10895 6278575ac0e52f4f9b788c57b1b00e5f 315 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 54 281 5.6E-20 T 29-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 SMALA_RS10895 6278575ac0e52f4f9b788c57b1b00e5f 315 Pfam PF08282 haloacid dehalogenase-like hydrolase 55 148 4.1E-12 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS10895 6278575ac0e52f4f9b788c57b1b00e5f 315 Pfam PF08282 haloacid dehalogenase-like hydrolase 221 308 2.5E-26 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS21435 586898a853d8cc7b1b546371f056a93f 217 SUPERFAMILY SSF52218 30 192 6.1E-40 T 29-03-2018 IPR029039 Flavoprotein-like domain SMALA_RS21435 586898a853d8cc7b1b546371f056a93f 217 Gene3D G3DSA:3.40.50.360 16 215 7.9E-44 T 29-03-2018 IPR029039 Flavoprotein-like domain SMALA_RS21435 586898a853d8cc7b1b546371f056a93f 217 Pfam PF03358 NADPH-dependent FMN reductase 30 172 1.3E-38 T 29-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 SMALA_RS27065 0ec63fa0db0855a317231e7d0dbc5f61 218 SMART SM00862 145 216 8.1E-26 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS27065 0ec63fa0db0855a317231e7d0dbc5f61 218 Gene3D G3DSA:3.40.50.2300 1 117 6.5E-39 T 29-03-2018 SMALA_RS27065 0ec63fa0db0855a317231e7d0dbc5f61 218 Pfam PF00072 Response regulator receiver domain 4 112 2.2E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS27065 0ec63fa0db0855a317231e7d0dbc5f61 218 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 216 3.0E-23 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS27065 0ec63fa0db0855a317231e7d0dbc5f61 218 SMART SM00448 1 112 1.5E-40 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS27065 0ec63fa0db0855a317231e7d0dbc5f61 218 Gene3D G3DSA:1.10.10.10 118 218 1.1E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS27065 0ec63fa0db0855a317231e7d0dbc5f61 218 SUPERFAMILY SSF46894 119 217 5.67E-27 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS27065 0ec63fa0db0855a317231e7d0dbc5f61 218 SUPERFAMILY SSF52172 1 129 2.13E-39 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS06385 e6922a1dbf6928dc39575d2afad0afa7 511 Gene3D G3DSA:1.20.1250.20 17 209 4.9E-33 T 29-03-2018 SMALA_RS06385 e6922a1dbf6928dc39575d2afad0afa7 511 SUPERFAMILY SSF103473 480 508 2.62E-69 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS06385 e6922a1dbf6928dc39575d2afad0afa7 511 SUPERFAMILY SSF103473 12 208 2.62E-69 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS06385 e6922a1dbf6928dc39575d2afad0afa7 511 SUPERFAMILY SSF103473 258 429 2.62E-69 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS06385 e6922a1dbf6928dc39575d2afad0afa7 511 Gene3D G3DSA:1.20.1250.20 269 510 4.0E-26 T 29-03-2018 SMALA_RS06385 e6922a1dbf6928dc39575d2afad0afa7 511 Pfam PF07690 Major Facilitator Superfamily 28 419 9.1E-53 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS17850 3513a9e20e2910b14241f2f9340dd5dd 269 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 143 163 - T 29-03-2018 IPR001110 Uncharacterised protein family UPF0012, conserved site SMALA_RS17850 3513a9e20e2910b14241f2f9340dd5dd 269 Gene3D G3DSA:3.60.110.10 1 262 4.0E-65 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMALA_RS17850 3513a9e20e2910b14241f2f9340dd5dd 269 SUPERFAMILY SSF56317 1 254 5.1E-66 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMALA_RS17850 3513a9e20e2910b14241f2f9340dd5dd 269 Pfam PF00795 Carbon-nitrogen hydrolase 2 245 3.5E-39 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMALA_RS11380 36d96045bcc791a46d7e380f99321689 361 SUPERFAMILY SSF51735 153 328 4.83E-40 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS11380 36d96045bcc791a46d7e380f99321689 361 Gene3D G3DSA:3.40.50.720 191 306 7.0E-19 T 29-03-2018 SMALA_RS11380 36d96045bcc791a46d7e380f99321689 361 Pfam PF00107 Zinc-binding dehydrogenase 192 313 8.3E-25 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMALA_RS11380 36d96045bcc791a46d7e380f99321689 361 Gene3D G3DSA:3.90.180.10 1 190 6.4E-54 T 29-03-2018 SMALA_RS11380 36d96045bcc791a46d7e380f99321689 361 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 149 6.9E-27 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS11380 36d96045bcc791a46d7e380f99321689 361 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 60 74 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 SMALA_RS11380 36d96045bcc791a46d7e380f99321689 361 SMART SM00829 10 355 4.1E-6 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS11380 36d96045bcc791a46d7e380f99321689 361 SUPERFAMILY SSF50129 2 196 9.89E-46 T 29-03-2018 IPR011032 GroES-like SMALA_RS11380 36d96045bcc791a46d7e380f99321689 361 SUPERFAMILY SSF50129 317 359 1.88E-5 T 29-03-2018 IPR011032 GroES-like SMALA_RS37075 a97a0754f774dc264dd17ce85dca5535 110 Gene3D G3DSA:3.30.70.120 1 105 2.2E-28 T 29-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal SMALA_RS37075 a97a0754f774dc264dd17ce85dca5535 110 SUPERFAMILY SSF54913 2 105 5.56E-29 T 29-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta SMALA_RS37075 a97a0754f774dc264dd17ce85dca5535 110 Pfam PF03091 CutA1 divalent ion tolerance protein 7 102 1.7E-26 T 29-03-2018 IPR004323 Divalent ion tolerance protein, CutA GO:0010038 SMALA_RS32440 80f9a0aa0baf1cf71833ed469d0fac06 314 PRINTS PR00474 Glutamate 5-kinase family signature 62 76 1.5E-8 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 SMALA_RS32440 80f9a0aa0baf1cf71833ed469d0fac06 314 PRINTS PR00474 Glutamate 5-kinase family signature 246 266 1.5E-8 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 SMALA_RS32440 80f9a0aa0baf1cf71833ed469d0fac06 314 PRINTS PR00474 Glutamate 5-kinase family signature 195 222 1.5E-8 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 SMALA_RS32440 80f9a0aa0baf1cf71833ed469d0fac06 314 SUPERFAMILY SSF53633 10 297 6.02E-85 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase SMALA_RS32440 80f9a0aa0baf1cf71833ed469d0fac06 314 PIRSF PIRSF000728 16 295 3.0E-95 T 29-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 SMALA_RS32440 80f9a0aa0baf1cf71833ed469d0fac06 314 Pfam PF00696 Amino acid kinase family 31 272 1.3E-48 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase SMALA_RS32440 80f9a0aa0baf1cf71833ed469d0fac06 314 Hamap MF_00082_B Acetylglutamate kinase [argB]. 29 296 34.018 T 29-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 SMALA_RS32440 80f9a0aa0baf1cf71833ed469d0fac06 314 TIGRFAM TIGR00761 argB: acetylglutamate kinase 32 270 4.1E-71 T 29-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 SMALA_RS32440 80f9a0aa0baf1cf71833ed469d0fac06 314 Gene3D G3DSA:3.40.1160.10 1 302 2.1E-74 T 29-03-2018 SMALA_RS37095 1fdb68911bb5c547bfcbbc86d9e7b9f9 116 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 65 107 2.3E-5 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMALA_RS37095 1fdb68911bb5c547bfcbbc86d9e7b9f9 116 Gene3D G3DSA:3.10.180.10 15 115 8.7E-19 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS37095 1fdb68911bb5c547bfcbbc86d9e7b9f9 116 SUPERFAMILY SSF54593 6 114 5.37E-21 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS03170 8aa2be81aa9a04fc867db32dd3ead479 159 SUPERFAMILY SSF46785 13 153 5.55E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS03170 8aa2be81aa9a04fc867db32dd3ead479 159 Pfam PF01047 MarR family 45 102 1.9E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS03170 8aa2be81aa9a04fc867db32dd3ead479 159 SMART SM00347 38 138 2.5E-13 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS03170 8aa2be81aa9a04fc867db32dd3ead479 159 Gene3D G3DSA:1.10.10.10 3 158 1.1E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS10805 f6eaa07c8a7234a524b8bc4b98c6b0c3 240 Gene3D G3DSA:3.90.850.10 17 233 0.001 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 SMALA_RS10805 f6eaa07c8a7234a524b8bc4b98c6b0c3 240 SUPERFAMILY SSF56529 54 228 8.5E-8 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 SMALA_RS10805 f6eaa07c8a7234a524b8bc4b98c6b0c3 240 Pfam PF11010 Protein of unknown function (DUF2848) 36 230 1.0E-78 T 29-03-2018 IPR021269 Protein of unknown function DUF2848 SMALA_RS34850 b8d590a179da17d428ce303ddf24d7a3 207 Pfam PF03029 Conserved hypothetical ATP binding protein 30 196 4.5E-23 T 29-03-2018 IPR004130 GPN-loop GTPase SMALA_RS34850 b8d590a179da17d428ce303ddf24d7a3 207 SUPERFAMILY SSF52540 25 198 4.73E-20 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS34850 b8d590a179da17d428ce303ddf24d7a3 207 PRINTS PR00449 Transforming protein P21 ras signature 174 196 2.0E-6 T 29-03-2018 SMALA_RS34850 b8d590a179da17d428ce303ddf24d7a3 207 PRINTS PR00449 Transforming protein P21 ras signature 26 47 2.0E-6 T 29-03-2018 SMALA_RS34850 b8d590a179da17d428ce303ddf24d7a3 207 PRINTS PR00449 Transforming protein P21 ras signature 84 106 2.0E-6 T 29-03-2018 SMALA_RS34850 b8d590a179da17d428ce303ddf24d7a3 207 Gene3D G3DSA:3.40.50.300 17 201 2.1E-17 T 29-03-2018 SMALA_RS02260 33a0f61036463c19514f8892c4508c26 144 SUPERFAMILY SSF52304 3 142 3.66E-49 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SMALA_RS02260 33a0f61036463c19514f8892c4508c26 144 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 5 124 1.0E-65 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SMALA_RS02260 33a0f61036463c19514f8892c4508c26 144 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 144 48.977 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SMALA_RS02260 33a0f61036463c19514f8892c4508c26 144 Gene3D G3DSA:3.40.50.9100 1 144 3.2E-46 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SMALA_RS02260 33a0f61036463c19514f8892c4508c26 144 Pfam PF01220 Dehydroquinase class II 4 138 4.1E-44 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SMALA_RS02260 33a0f61036463c19514f8892c4508c26 144 PIRSF PIRSF001399 1 144 3.4E-50 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SMALA_RS02260 33a0f61036463c19514f8892c4508c26 144 ProSitePatterns PS01029 Dehydroquinase class II signature. 7 24 - T 29-03-2018 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SMALA_RS42225 8ebcae9ab33e0edf389e973b0bc138ac 436 SUPERFAMILY SSF56059 111 344 3.14E-24 T 29-03-2018 SMALA_RS42225 8ebcae9ab33e0edf389e973b0bc138ac 436 Gene3D G3DSA:3.30.470.20 125 413 1.2E-34 T 29-03-2018 SMALA_RS42225 8ebcae9ab33e0edf389e973b0bc138ac 436 Gene3D G3DSA:3.40.50.20 30 124 1.1E-6 T 29-03-2018 SMALA_RS42225 8ebcae9ab33e0edf389e973b0bc138ac 436 Pfam PF13535 ATP-grasp domain 158 301 1.2E-15 T 29-03-2018 SMALA_RS02535 15b8dae855d6a51d207d91368bb7ad9d 186 Pfam PF00440 Bacterial regulatory proteins, tetR family 2 46 3.1E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS02535 15b8dae855d6a51d207d91368bb7ad9d 186 SUPERFAMILY SSF46689 3 60 1.23E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS02535 15b8dae855d6a51d207d91368bb7ad9d 186 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 73 181 4.6E-7 T 29-03-2018 SMALA_RS02535 15b8dae855d6a51d207d91368bb7ad9d 186 SUPERFAMILY SSF48498 71 169 2.06E-7 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS02535 15b8dae855d6a51d207d91368bb7ad9d 186 Gene3D G3DSA:1.10.357.10 48 179 9.9E-13 T 29-03-2018 SMALA_RS02535 15b8dae855d6a51d207d91368bb7ad9d 186 Gene3D G3DSA:1.10.10.60 1 47 2.6E-13 T 29-03-2018 SMALA_RS41765 bc7b04463108bb4ef0426c6cb70f0486 248 SUPERFAMILY SSF53335 6 244 1.51E-41 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS41765 bc7b04463108bb4ef0426c6cb70f0486 248 PIRSF PIRSF034653 1 248 4.3E-114 T 29-03-2018 IPR017031 Predicted S-adenosyl-L-methionine dependent methyltransferase, YjhP-type SMALA_RS41765 bc7b04463108bb4ef0426c6cb70f0486 248 Pfam PF13649 Methyltransferase domain 40 134 1.5E-9 T 29-03-2018 SMALA_RS41765 bc7b04463108bb4ef0426c6cb70f0486 248 Gene3D G3DSA:3.40.50.150 1 248 7.6E-38 T 29-03-2018 SMALA_RS01455 53be6e7ffec033bcf518e2ab0bf1bce9 201 Gene3D G3DSA:3.40.33.10 72 198 2.8E-22 T 29-03-2018 IPR014044 CAP domain SMALA_RS01455 53be6e7ffec033bcf518e2ab0bf1bce9 201 SMART SM00198 78 194 0.0092 T 29-03-2018 IPR014044 CAP domain SMALA_RS01455 53be6e7ffec033bcf518e2ab0bf1bce9 201 Pfam PF00188 Cysteine-rich secretory protein family 85 197 1.9E-21 T 29-03-2018 IPR014044 CAP domain SMALA_RS01455 53be6e7ffec033bcf518e2ab0bf1bce9 201 SUPERFAMILY SSF55797 78 197 4.45E-26 T 29-03-2018 IPR014044 CAP domain SMALA_RS39395 a801636f479b86b901f7b818376e9744 413 Gene3D G3DSA:1.20.1250.20 1 195 5.5E-19 T 29-03-2018 SMALA_RS39395 a801636f479b86b901f7b818376e9744 413 Pfam PF05977 Transmembrane secretion effector 9 390 4.9E-46 T 29-03-2018 IPR010290 Transmembrane secretion effector SMALA_RS39395 a801636f479b86b901f7b818376e9744 413 SUPERFAMILY SSF103473 10 401 3.4E-40 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS39395 a801636f479b86b901f7b818376e9744 413 Gene3D G3DSA:1.20.1250.20 207 406 4.2E-16 T 29-03-2018 SMALA_RS06770 0b5ea4be8949bea125bfc706d539cd73 303 Gene3D G3DSA:3.40.190.10 83 174 2.6E-19 T 29-03-2018 SMALA_RS06770 0b5ea4be8949bea125bfc706d539cd73 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 4.9E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS06770 0b5ea4be8949bea125bfc706d539cd73 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 4.9E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS06770 0b5ea4be8949bea125bfc706d539cd73 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 4.9E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS06770 0b5ea4be8949bea125bfc706d539cd73 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 5.1E-21 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS06770 0b5ea4be8949bea125bfc706d539cd73 303 Gene3D G3DSA:1.10.10.10 1 82 8.5E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS06770 0b5ea4be8949bea125bfc706d539cd73 303 SUPERFAMILY SSF53850 103 280 7.44E-26 T 29-03-2018 SMALA_RS06770 0b5ea4be8949bea125bfc706d539cd73 303 Pfam PF03466 LysR substrate binding domain 104 278 2.3E-28 T 29-03-2018 IPR005119 LysR, substrate-binding SMALA_RS06770 0b5ea4be8949bea125bfc706d539cd73 303 Gene3D G3DSA:3.40.190.10 175 256 6.0E-14 T 29-03-2018 SMALA_RS06770 0b5ea4be8949bea125bfc706d539cd73 303 SUPERFAMILY SSF46785 3 84 7.19E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS21485 3d733ef3ac6bea7310999a9858670653 95 Gene3D G3DSA:2.60.40.1120 13 95 3.5E-7 T 29-03-2018 SMALA_RS21485 3d733ef3ac6bea7310999a9858670653 95 Pfam PF07210 Protein of unknown function (DUF1416) 2 95 2.4E-35 T 29-03-2018 IPR010814 Protein of unknown function DUF1416 SMALA_RS21485 3d733ef3ac6bea7310999a9858670653 95 SUPERFAMILY SSF49452 17 88 2.35E-5 T 29-03-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 SMALA_RS19115 00280d275614d9c6ad5d74bfe564e02e 245 SMART SM00448 20 131 5.4E-42 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS19115 00280d275614d9c6ad5d74bfe564e02e 245 Gene3D G3DSA:3.40.50.2300 9 142 1.4E-39 T 29-03-2018 SMALA_RS19115 00280d275614d9c6ad5d74bfe564e02e 245 Gene3D G3DSA:1.10.10.10 143 245 3.0E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS19115 00280d275614d9c6ad5d74bfe564e02e 245 Pfam PF00072 Response regulator receiver domain 22 131 1.2E-28 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS19115 00280d275614d9c6ad5d74bfe564e02e 245 SUPERFAMILY SSF52172 18 198 1.71E-42 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS19115 00280d275614d9c6ad5d74bfe564e02e 245 Pfam PF00486 Transcriptional regulatory protein, C terminal 167 240 6.7E-25 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS19115 00280d275614d9c6ad5d74bfe564e02e 245 SMART SM00862 167 241 1.5E-26 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS33375 b8a7e0d06b3337b929ddc6d7646e1bb7 387 Gene3D G3DSA:1.10.540.10 3 114 2.9E-22 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS33375 b8a7e0d06b3337b929ddc6d7646e1bb7 387 SUPERFAMILY SSF56645 13 219 4.06E-34 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMALA_RS33375 b8a7e0d06b3337b929ddc6d7646e1bb7 387 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 14 109 8.5E-17 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS33375 b8a7e0d06b3337b929ddc6d7646e1bb7 387 SUPERFAMILY SSF47203 228 364 3.87E-13 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMALA_RS33375 b8a7e0d06b3337b929ddc6d7646e1bb7 387 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 236 362 8.8E-11 T 29-03-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain SMALA_RS33375 b8a7e0d06b3337b929ddc6d7646e1bb7 387 Gene3D G3DSA:2.40.110.10 115 213 1.9E-6 T 29-03-2018 SMALA_RS33375 b8a7e0d06b3337b929ddc6d7646e1bb7 387 PIRSF PIRSF016578 2 382 5.0E-19 T 29-03-2018 SMALA_RS33375 b8a7e0d06b3337b929ddc6d7646e1bb7 387 Gene3D G3DSA:1.20.140.10 214 381 5.7E-15 T 29-03-2018 SMALA_RS18325 8067737632b8b1fc58a8de1866388208 333 Pfam PF00348 Polyprenyl synthetase 36 215 1.3E-22 T 29-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 SMALA_RS18325 8067737632b8b1fc58a8de1866388208 333 Gene3D G3DSA:1.10.600.10 2 223 1.6E-42 T 29-03-2018 IPR008949 Isoprenoid synthase domain SMALA_RS18325 8067737632b8b1fc58a8de1866388208 333 Gene3D G3DSA:1.10.600.10 226 320 2.6E-11 T 29-03-2018 IPR008949 Isoprenoid synthase domain SMALA_RS18325 8067737632b8b1fc58a8de1866388208 333 SUPERFAMILY SSF48576 21 311 3.12E-45 T 29-03-2018 IPR008949 Isoprenoid synthase domain SMALA_RS31845 1ff9a6f6d2f53b5e72622cd9193041ab 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 4.9E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS31845 1ff9a6f6d2f53b5e72622cd9193041ab 303 Gene3D G3DSA:3.40.190.10 179 271 4.9E-15 T 29-03-2018 SMALA_RS31845 1ff9a6f6d2f53b5e72622cd9193041ab 303 SUPERFAMILY SSF53850 88 300 3.14E-29 T 29-03-2018 SMALA_RS31845 1ff9a6f6d2f53b5e72622cd9193041ab 303 Gene3D G3DSA:1.10.10.10 1 83 2.5E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS31845 1ff9a6f6d2f53b5e72622cd9193041ab 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 4.3E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS31845 1ff9a6f6d2f53b5e72622cd9193041ab 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 4.3E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS31845 1ff9a6f6d2f53b5e72622cd9193041ab 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 4.3E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS31845 1ff9a6f6d2f53b5e72622cd9193041ab 303 Gene3D G3DSA:3.40.190.10 84 178 4.0E-20 T 29-03-2018 SMALA_RS31845 1ff9a6f6d2f53b5e72622cd9193041ab 303 SUPERFAMILY SSF46785 3 110 6.31E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS31845 1ff9a6f6d2f53b5e72622cd9193041ab 303 Pfam PF03466 LysR substrate binding domain 88 297 7.3E-33 T 29-03-2018 IPR005119 LysR, substrate-binding SMALA_RS18080 463622249b6f7574e92fe156526d700d 610 Gene3D G3DSA:3.40.630.30 343 553 6.3E-5 T 29-03-2018 SMALA_RS18080 463622249b6f7574e92fe156526d700d 610 Pfam PF16995 Transmembrane region of lysyl-tRNA synthetase 27 221 2.8E-12 T 29-03-2018 IPR031553 Lysyl-tRNA synthetase, N-terminal transmembrane region KEGG: 00970+6.1.1.6 SMALA_RS18080 463622249b6f7574e92fe156526d700d 610 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 247 556 6.9E-103 T 29-03-2018 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal SMALA_RS06085 04dd383da389452376396fd844613ac4 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 8.8E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS06085 04dd383da389452376396fd844613ac4 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 8.8E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS06085 04dd383da389452376396fd844613ac4 220 SUPERFAMILY SSF48498 90 212 2.09E-9 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS06085 04dd383da389452376396fd844613ac4 220 SUPERFAMILY SSF46689 8 80 1.05E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS06085 04dd383da389452376396fd844613ac4 220 Gene3D G3DSA:1.10.357.10 67 215 4.6E-19 T 29-03-2018 SMALA_RS06085 04dd383da389452376396fd844613ac4 220 Gene3D G3DSA:1.10.10.60 5 66 7.3E-19 T 29-03-2018 SMALA_RS06085 04dd383da389452376396fd844613ac4 220 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 65 2.7E-14 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS12970 5914b4d01bd7758a130f6502206b1e41 410 Pfam PF04055 Radical SAM superfamily 35 213 1.3E-22 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 SMALA_RS12970 5914b4d01bd7758a130f6502206b1e41 410 SMART SM00729 29 259 3.9E-62 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 SMALA_RS12970 5914b4d01bd7758a130f6502206b1e41 410 Gene3D G3DSA:3.20.20.70 25 342 7.7E-51 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS12970 5914b4d01bd7758a130f6502206b1e41 410 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 32 364 8.6E-70 T 29-03-2018 IPR004559 Coproporphyrinogen III oxidase, oxygen-independent related GO:0004109|GO:0005737|GO:0006779|GO:0055114 SMALA_RS12970 5914b4d01bd7758a130f6502206b1e41 410 SUPERFAMILY SSF102114 21 408 5.1E-108 T 29-03-2018 SMALA_RS15435 532670ca1ffb7aa3e69d053cfced5c13 434 SUPERFAMILY SSF53850 26 429 2.43E-75 T 29-03-2018 SMALA_RS15435 532670ca1ffb7aa3e69d053cfced5c13 434 Gene3D G3DSA:3.40.190.10 25 209 2.4E-34 T 29-03-2018 SMALA_RS15435 532670ca1ffb7aa3e69d053cfced5c13 434 Gene3D G3DSA:3.40.190.10 236 386 1.9E-11 T 29-03-2018 SMALA_RS15435 532670ca1ffb7aa3e69d053cfced5c13 434 Pfam PF13416 Bacterial extracellular solute-binding protein 60 373 2.6E-36 T 29-03-2018 SMALA_RS07300 e9ba7933c963943c77790d08bdca481f 532 PIRSF PIRSF002741 1 526 2.5E-77 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 SMALA_RS07300 e9ba7933c963943c77790d08bdca481f 532 SUPERFAMILY SSF53850 49 527 1.5E-97 T 29-03-2018 SMALA_RS07300 e9ba7933c963943c77790d08bdca481f 532 Gene3D G3DSA:3.10.105.10 296 501 1.0E-40 T 29-03-2018 SMALA_RS07300 e9ba7933c963943c77790d08bdca481f 532 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 83 450 1.5E-74 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain SMALA_RS07300 e9ba7933c963943c77790d08bdca481f 532 Gene3D G3DSA:3.90.76.10 49 193 2.5E-30 T 29-03-2018 SMALA_RS07300 e9ba7933c963943c77790d08bdca481f 532 Gene3D G3DSA:3.40.190.10 194 295 1.1E-19 T 29-03-2018 SMALA_RS17470 68dac3fb62713ac453a79e960f13bb3b 315 SUPERFAMILY SSF55874 203 310 1.66E-13 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS17470 68dac3fb62713ac453a79e960f13bb3b 315 Pfam PF00672 HAMP domain 58 104 6.7E-8 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMALA_RS17470 68dac3fb62713ac453a79e960f13bb3b 315 SMART SM00387 222 312 0.005 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS17470 68dac3fb62713ac453a79e960f13bb3b 315 Pfam PF07730 Histidine kinase 121 185 2.4E-17 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMALA_RS17470 68dac3fb62713ac453a79e960f13bb3b 315 SMART SM00304 56 108 2.1E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMALA_RS17470 68dac3fb62713ac453a79e960f13bb3b 315 Gene3D G3DSA:3.30.565.10 182 315 1.4E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS40210 5bc5a59110ae5d7560d0530bf0fac68c 269 SMART SM00382 43 228 1.2E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS40210 5bc5a59110ae5d7560d0530bf0fac68c 269 Gene3D G3DSA:3.40.50.300 17 248 1.1E-61 T 29-03-2018 SMALA_RS40210 5bc5a59110ae5d7560d0530bf0fac68c 269 SUPERFAMILY SSF52540 21 239 2.55E-54 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS40210 5bc5a59110ae5d7560d0530bf0fac68c 269 Pfam PF00005 ABC transporter 37 179 9.4E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS35810 c4cdea63b91dda64682ccefd476d5360 519 SMART SM00046 196 319 1.9E-4 T 29-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 SMALA_RS35810 c4cdea63b91dda64682ccefd476d5360 519 Pfam PF00781 Diacylglycerol kinase catalytic domain 197 318 1.9E-14 T 29-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 SMALA_RS35810 c4cdea63b91dda64682ccefd476d5360 519 SUPERFAMILY SSF48317 21 174 1.23E-39 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMALA_RS35810 c4cdea63b91dda64682ccefd476d5360 519 SMART SM00014 60 169 2.7E-22 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMALA_RS35810 c4cdea63b91dda64682ccefd476d5360 519 SUPERFAMILY SSF111331 196 493 1.2E-44 T 29-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain SMALA_RS35810 c4cdea63b91dda64682ccefd476d5360 519 Gene3D G3DSA:1.20.144.10 8 188 5.0E-29 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMALA_RS35810 c4cdea63b91dda64682ccefd476d5360 519 Pfam PF01569 PAP2 superfamily 64 174 1.8E-20 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMALA_RS35810 c4cdea63b91dda64682ccefd476d5360 519 Gene3D G3DSA:3.40.50.10330 193 324 2.3E-14 T 29-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 SMALA_RS01870 82be50674998ab0ddfe436d0b04dcb98 216 SUPERFAMILY SSF46689 26 86 2.29E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS01870 82be50674998ab0ddfe436d0b04dcb98 216 SUPERFAMILY SSF48498 96 206 2.0E-25 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS01870 82be50674998ab0ddfe436d0b04dcb98 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 48 1.4E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS01870 82be50674998ab0ddfe436d0b04dcb98 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 56 79 1.4E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS01870 82be50674998ab0ddfe436d0b04dcb98 216 Gene3D G3DSA:1.10.10.60 14 76 3.9E-17 T 29-03-2018 SMALA_RS01870 82be50674998ab0ddfe436d0b04dcb98 216 Gene3D G3DSA:1.10.357.10 77 216 2.8E-26 T 29-03-2018 SMALA_RS01870 82be50674998ab0ddfe436d0b04dcb98 216 Pfam PF16859 Bacterial transcriptional repressor C-terminal 93 203 1.5E-32 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS01870 82be50674998ab0ddfe436d0b04dcb98 216 Pfam PF00440 Bacterial regulatory proteins, tetR family 36 78 6.5E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS39645 ea4394355b8d6db870346514f97eed20 313 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 221 237 - T 29-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site SMALA_RS39645 ea4394355b8d6db870346514f97eed20 313 SUPERFAMILY SSF52283 34 137 4.25E-32 T 29-03-2018 SMALA_RS39645 ea4394355b8d6db870346514f97eed20 313 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 35 310 1.1E-29 T 29-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 SMALA_RS39645 ea4394355b8d6db870346514f97eed20 313 SUPERFAMILY SSF51735 103 282 1.48E-49 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS39645 ea4394355b8d6db870346514f97eed20 313 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 112 281 4.4E-49 T 29-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 SMALA_RS39645 ea4394355b8d6db870346514f97eed20 313 Gene3D G3DSA:3.40.50.720 118 284 8.2E-47 T 29-03-2018 SMALA_RS39645 ea4394355b8d6db870346514f97eed20 313 Gene3D G3DSA:3.40.50.720 4 117 4.2E-31 T 29-03-2018 SMALA_RS39645 ea4394355b8d6db870346514f97eed20 313 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 147 174 - T 29-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 SMALA_RS16375 9c6b7dddf54387c1b691d019094d038d 344 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 45 63 6.4E-8 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMALA_RS16375 9c6b7dddf54387c1b691d019094d038d 344 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 31 45 6.4E-8 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMALA_RS16375 9c6b7dddf54387c1b691d019094d038d 344 SMART SM00420 13 65 2.8E-14 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMALA_RS16375 9c6b7dddf54387c1b691d019094d038d 344 SMART SM01134 80 241 6.6E-65 T 29-03-2018 SMALA_RS16375 9c6b7dddf54387c1b691d019094d038d 344 Pfam PF08220 DeoR-like helix-turn-helix domain 13 65 2.6E-14 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMALA_RS16375 9c6b7dddf54387c1b691d019094d038d 344 Gene3D G3DSA:3.40.50.1360 73 239 1.3E-38 T 29-03-2018 SMALA_RS16375 9c6b7dddf54387c1b691d019094d038d 344 SUPERFAMILY SSF100950 83 241 1.67E-29 T 29-03-2018 SMALA_RS16375 9c6b7dddf54387c1b691d019094d038d 344 Pfam PF00455 DeoR C terminal sensor domain 83 240 4.2E-50 T 29-03-2018 IPR014036 DeoR C-terminal sensor domain SMALA_RS16375 9c6b7dddf54387c1b691d019094d038d 344 Gene3D G3DSA:1.10.10.10 4 65 3.9E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS16375 9c6b7dddf54387c1b691d019094d038d 344 ProSitePatterns PS00894 DeoR-type HTH domain signature. 13 47 - T 29-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 SMALA_RS16375 9c6b7dddf54387c1b691d019094d038d 344 SUPERFAMILY SSF46785 12 66 2.23E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS35455 3225647b44775a478883e041c393c95e 312 SUPERFAMILY SSF161098 72 294 1.13E-53 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS35455 3225647b44775a478883e041c393c95e 312 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 103 300 8.7E-17 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS35455 3225647b44775a478883e041c393c95e 312 Gene3D G3DSA:1.20.58.370 8 45 1.6E-4 T 29-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain SMALA_RS35455 3225647b44775a478883e041c393c95e 312 Gene3D G3DSA:1.10.3720.10 46 310 9.5E-48 T 29-03-2018 SMALA_RS25010 df8071b71548444c970a6a5467557f13 174 SUPERFAMILY SSF46785 3 167 2.31E-35 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS25010 df8071b71548444c970a6a5467557f13 174 Pfam PF03551 Transcriptional regulator PadR-like family 7 77 1.1E-14 T 29-03-2018 IPR005149 Transcription regulator PadR, N-terminal SMALA_RS25010 df8071b71548444c970a6a5467557f13 174 Gene3D G3DSA:1.10.10.10 1 91 1.6E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS03705 74721c16614c0497e7d717896e72700b 520 Pfam PF00501 AMP-binding enzyme 8 414 1.4E-69 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS03705 74721c16614c0497e7d717896e72700b 520 Gene3D G3DSA:3.40.50.980 3 166 2.3E-32 T 29-03-2018 SMALA_RS03705 74721c16614c0497e7d717896e72700b 520 Pfam PF13193 AMP-binding enzyme C-terminal domain 423 501 3.0E-21 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS03705 74721c16614c0497e7d717896e72700b 520 SUPERFAMILY SSF56801 5 513 1.19E-120 T 29-03-2018 SMALA_RS03705 74721c16614c0497e7d717896e72700b 520 Gene3D G3DSA:2.30.38.10 324 407 1.1E-13 T 29-03-2018 SMALA_RS03705 74721c16614c0497e7d717896e72700b 520 ProSitePatterns PS00455 Putative AMP-binding domain signature. 161 172 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS03705 74721c16614c0497e7d717896e72700b 520 Gene3D G3DSA:3.30.300.30 410 520 2.7E-31 T 29-03-2018 SMALA_RS03705 74721c16614c0497e7d717896e72700b 520 Gene3D G3DSA:3.40.50.980 167 323 3.6E-32 T 29-03-2018 SMALA_RS09815 dc3ddbcb2a6391f9a1b0b8d6fe656600 584 Gene3D G3DSA:1.10.3470.10 196 543 4.3E-42 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SMALA_RS09815 dc3ddbcb2a6391f9a1b0b8d6fe656600 584 Pfam PF02653 Branched-chain amino acid transport system / permease component 256 541 4.5E-42 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 SMALA_RS02660 dd592263475136ebc4f54d4ebb442f6e 532 Gene3D G3DSA:3.20.20.80 10 470 5.6E-117 T 29-03-2018 SMALA_RS02660 dd592263475136ebc4f54d4ebb442f6e 532 SMART SM00642 21 407 1.4E-114 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SMALA_RS02660 dd592263475136ebc4f54d4ebb442f6e 532 SUPERFAMILY SSF51445 11 467 5.53E-117 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS02660 dd592263475136ebc4f54d4ebb442f6e 532 Pfam PF11941 Domain of unknown function (DUF3459) 453 530 1.1E-6 T 29-03-2018 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) SMALA_RS02660 dd592263475136ebc4f54d4ebb442f6e 532 Pfam PF00128 Alpha amylase, catalytic domain 36 382 7.4E-71 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SMALA_RS04610 6710d671a6f65e379974d4d894b8c2cc 340 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 46 272 5.5E-103 T 29-03-2018 IPR022488 Polyphosphate kinase-2-related SMALA_RS04610 6710d671a6f65e379974d4d894b8c2cc 340 TIGRFAM TIGR03707 PPK2_P_aer: polyphosphate kinase 2 45 273 1.3E-115 T 29-03-2018 IPR022486 Polyphosphate kinase 2, PA0141 GO:0006793|GO:0008976 SMALA_RS04610 6710d671a6f65e379974d4d894b8c2cc 340 Gene3D G3DSA:3.40.50.300 16 293 1.8E-102 T 29-03-2018 SMALA_RS04610 6710d671a6f65e379974d4d894b8c2cc 340 SUPERFAMILY SSF52540 77 263 9.4E-30 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS14205 befa4437ebf8f6cfacb6b32ac6a45714 310 Pfam PF00682 HMGL-like 15 286 1.8E-47 T 29-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 SMALA_RS14205 befa4437ebf8f6cfacb6b32ac6a45714 310 Gene3D G3DSA:3.20.20.70 11 308 1.8E-107 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS14205 befa4437ebf8f6cfacb6b32ac6a45714 310 SUPERFAMILY SSF51569 12 303 4.03E-70 T 29-03-2018 SMALA_RS12835 d625327a6536e4eac07f4ed131512333 191 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 141 185 9.5E-7 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 SMALA_RS12835 d625327a6536e4eac07f4ed131512333 191 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 33 54 0.031 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 SMALA_RS12835 d625327a6536e4eac07f4ed131512333 191 Gene3D G3DSA:1.10.1780.10 1 72 1.2E-11 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 SMALA_RS12835 d625327a6536e4eac07f4ed131512333 191 Gene3D G3DSA:1.10.1780.10 73 189 2.3E-23 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 SMALA_RS12835 d625327a6536e4eac07f4ed131512333 191 SUPERFAMILY SSF81923 113 184 7.59E-9 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 SMALA_RS12835 d625327a6536e4eac07f4ed131512333 191 SUPERFAMILY SSF81923 3 56 5.62E-7 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 SMALA_RS27630 3274a0be2780c171687588038fe14897 175 SUPERFAMILY SSF102405 1 174 6.41E-43 T 29-03-2018 SMALA_RS27630 3274a0be2780c171687588038fe14897 175 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 2 167 3.0E-36 T 29-03-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG SMALA_RS27630 3274a0be2780c171687588038fe14897 175 Gene3D G3DSA:3.40.50.450 1 174 2.1E-38 T 29-03-2018 SMALA_RS27630 3274a0be2780c171687588038fe14897 175 Pfam PF03641 Possible lysine decarboxylase 44 171 3.1E-31 T 29-03-2018 IPR031100 LOG family SMALA_RS12590 22ce16e1925bea1a3482a19966cff296 353 SUPERFAMILY SSF46785 265 323 3.66E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS12590 22ce16e1925bea1a3482a19966cff296 353 Gene3D G3DSA:1.10.10.10 228 333 1.2E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS12590 22ce16e1925bea1a3482a19966cff296 353 Pfam PF12840 Helix-turn-helix domain 260 307 6.1E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS12590 22ce16e1925bea1a3482a19966cff296 353 SMART SM00418 251 322 4.5E-4 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS01875 242746f835daad248915e4f96db7feac 354 SUPERFAMILY SSF54506 171 351 4.24E-50 T 29-03-2018 SMALA_RS01875 242746f835daad248915e4f96db7feac 354 Gene3D G3DSA:3.10.310.10 4 180 2.1E-68 T 29-03-2018 SMALA_RS01875 242746f835daad248915e4f96db7feac 354 Pfam PF04303 PrpF protein 7 350 2.5E-99 T 29-03-2018 IPR007400 PrpF protein SMALA_RS01875 242746f835daad248915e4f96db7feac 354 Gene3D G3DSA:3.10.310.10 181 333 1.2E-43 T 29-03-2018 SMALA_RS01875 242746f835daad248915e4f96db7feac 354 SUPERFAMILY SSF54506 6 167 9.42E-59 T 29-03-2018 SMALA_RS11585 cd981ad87c8c80902635661c29f421a4 398 SMART SM00530 9 64 0.0012 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS11585 cd981ad87c8c80902635661c29f421a4 398 SUPERFAMILY SSF48452 154 361 2.83E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS11585 cd981ad87c8c80902635661c29f421a4 398 SUPERFAMILY SSF47413 9 58 1.27E-6 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS11585 cd981ad87c8c80902635661c29f421a4 398 Pfam PF13560 Helix-turn-helix domain 5 61 4.4E-9 T 29-03-2018 SMALA_RS11585 cd981ad87c8c80902635661c29f421a4 398 Gene3D G3DSA:1.25.40.10 146 377 2.5E-13 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS11585 cd981ad87c8c80902635661c29f421a4 398 Gene3D G3DSA:1.10.260.40 3 78 1.6E-9 T 29-03-2018 SMALA_RS30845 72f0081a801c552f9fbd756be0cb0ce8 272 Pfam PF00440 Bacterial regulatory proteins, tetR family 52 98 4.4E-14 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS30845 72f0081a801c552f9fbd756be0cb0ce8 272 SUPERFAMILY SSF46689 45 121 2.74E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS30845 72f0081a801c552f9fbd756be0cb0ce8 272 Gene3D G3DSA:1.10.357.10 28 272 3.1E-35 T 29-03-2018 SMALA_RS30845 72f0081a801c552f9fbd756be0cb0ce8 272 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 73 96 5.8E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS30845 72f0081a801c552f9fbd756be0cb0ce8 272 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 52 65 5.8E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS30845 72f0081a801c552f9fbd756be0cb0ce8 272 SUPERFAMILY SSF48498 121 185 2.3E-5 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS29930 6869bf02701e563e169b928e2ca9d641 426 Gene3D G3DSA:1.20.950.20 13 189 5.6E-8 T 29-03-2018 SMALA_RS29930 6869bf02701e563e169b928e2ca9d641 426 Pfam PF00174 Oxidoreductase molybdopterin binding domain 291 423 1.9E-20 T 29-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 SMALA_RS29930 6869bf02701e563e169b928e2ca9d641 426 Gene3D G3DSA:3.90.420.10 264 426 9.1E-31 T 29-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 SMALA_RS29930 6869bf02701e563e169b928e2ca9d641 426 SUPERFAMILY SSF56524 291 424 2.35E-30 T 29-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 SMALA_RS29930 6869bf02701e563e169b928e2ca9d641 426 PRINTS PR00407 Eukaryotic molybdopterin domain signature 394 407 2.8E-7 T 29-03-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 SMALA_RS29930 6869bf02701e563e169b928e2ca9d641 426 PRINTS PR00407 Eukaryotic molybdopterin domain signature 410 423 2.8E-7 T 29-03-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 SMALA_RS29930 6869bf02701e563e169b928e2ca9d641 426 PRINTS PR00407 Eukaryotic molybdopterin domain signature 328 343 2.8E-7 T 29-03-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 SMALA_RS16515 2e8413bcdf73e9f149c037f63b5c9b4a 574 SUPERFAMILY SSF52540 308 526 9.75E-42 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS16515 2e8413bcdf73e9f149c037f63b5c9b4a 574 Gene3D G3DSA:3.40.50.300 32 267 1.8E-49 T 29-03-2018 SMALA_RS16515 2e8413bcdf73e9f149c037f63b5c9b4a 574 ProSitePatterns PS00211 ABC transporters family signature. 440 454 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS16515 2e8413bcdf73e9f149c037f63b5c9b4a 574 Pfam PF00005 ABC transporter 58 203 6.3E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS16515 2e8413bcdf73e9f149c037f63b5c9b4a 574 Pfam PF00005 ABC transporter 311 467 5.3E-18 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS16515 2e8413bcdf73e9f149c037f63b5c9b4a 574 SUPERFAMILY SSF52540 41 260 1.54E-53 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS16515 2e8413bcdf73e9f149c037f63b5c9b4a 574 SMART SM00382 66 251 2.1E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS16515 2e8413bcdf73e9f149c037f63b5c9b4a 574 Gene3D G3DSA:3.40.50.300 287 533 1.9E-35 T 29-03-2018 SMALA_RS37500 85a829d2a3b2e109ede521a85beef7c3 540 Pfam PF01593 Flavin containing amine oxidoreductase 15 352 2.2E-11 T 29-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 SMALA_RS37500 85a829d2a3b2e109ede521a85beef7c3 540 Gene3D G3DSA:3.50.50.60 1 125 2.4E-15 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS37500 85a829d2a3b2e109ede521a85beef7c3 540 Gene3D G3DSA:3.50.50.60 126 301 1.4E-10 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS37500 85a829d2a3b2e109ede521a85beef7c3 540 SUPERFAMILY SSF51905 492 507 6.98E-34 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS37500 85a829d2a3b2e109ede521a85beef7c3 540 SUPERFAMILY SSF51905 5 333 6.98E-34 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS07410 c27adf8eaa3182330de9a2efbcd94ca1 409 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 39 334 1.8E-81 T 29-03-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 SMALA_RS07410 c27adf8eaa3182330de9a2efbcd94ca1 409 Hamap MF_01697 L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase [mshC]. 9 409 53.088 T 29-03-2018 IPR017812 Mycothiol ligase MshC GO:0010125|GO:0035446 SMALA_RS07410 c27adf8eaa3182330de9a2efbcd94ca1 409 SUPERFAMILY SSF52374 33 333 7.78E-67 T 29-03-2018 SMALA_RS07410 c27adf8eaa3182330de9a2efbcd94ca1 409 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 40 51 3.5E-18 T 29-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 SMALA_RS07410 c27adf8eaa3182330de9a2efbcd94ca1 409 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 76 85 3.5E-18 T 29-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 SMALA_RS07410 c27adf8eaa3182330de9a2efbcd94ca1 409 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 241 262 3.5E-18 T 29-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 SMALA_RS07410 c27adf8eaa3182330de9a2efbcd94ca1 409 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 210 228 3.5E-18 T 29-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 SMALA_RS07410 c27adf8eaa3182330de9a2efbcd94ca1 409 TIGRFAM TIGR03447 mycothiol_MshC: cysteine--1-D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase 3 409 9.8E-202 T 29-03-2018 IPR017812 Mycothiol ligase MshC GO:0010125|GO:0035446 SMALA_RS07410 c27adf8eaa3182330de9a2efbcd94ca1 409 Gene3D G3DSA:3.40.50.620 1 326 4.3E-65 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS07410 c27adf8eaa3182330de9a2efbcd94ca1 409 Gene3D G3DSA:1.20.120.640 327 409 4.2E-15 T 29-03-2018 SMALA_RS19900 df7ec1dd0916ebaa63b6bdf42f120b19 117 SMART SM00450 4 102 3.8E-19 T 29-03-2018 IPR001763 Rhodanese-like domain SMALA_RS19900 df7ec1dd0916ebaa63b6bdf42f120b19 117 SUPERFAMILY SSF52821 17 108 3.8E-28 T 29-03-2018 IPR001763 Rhodanese-like domain SMALA_RS19900 df7ec1dd0916ebaa63b6bdf42f120b19 117 Pfam PF00581 Rhodanese-like domain 19 98 2.5E-12 T 29-03-2018 IPR001763 Rhodanese-like domain SMALA_RS19900 df7ec1dd0916ebaa63b6bdf42f120b19 117 Gene3D G3DSA:3.40.250.10 4 117 1.2E-24 T 29-03-2018 IPR001763 Rhodanese-like domain SMALA_RS18670 23213106e8115c7bea2ebb62479b30e7 111 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 74 18.862 T 29-03-2018 IPR003482 Transcription factor WhiB SMALA_RS18670 23213106e8115c7bea2ebb62479b30e7 111 Pfam PF02467 Transcription factor WhiB 7 69 8.8E-25 T 29-03-2018 IPR034768 WhiB-like iron-sulfur binding domain SMALA_RS12145 683f562d156e7519ccbca9f5f795df70 339 SMART SM00829 22 335 8.7E-9 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS12145 683f562d156e7519ccbca9f5f795df70 339 Gene3D G3DSA:3.40.50.720 152 279 1.3E-28 T 29-03-2018 SMALA_RS12145 683f562d156e7519ccbca9f5f795df70 339 Pfam PF16884 N-terminal domain of oxidoreductase 9 115 5.6E-42 T 29-03-2018 SMALA_RS12145 683f562d156e7519ccbca9f5f795df70 339 SUPERFAMILY SSF50129 6 144 3.65E-43 T 29-03-2018 IPR011032 GroES-like SMALA_RS12145 683f562d156e7519ccbca9f5f795df70 339 SUPERFAMILY SSF51735 126 303 2.59E-50 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS12145 683f562d156e7519ccbca9f5f795df70 339 Pfam PF00107 Zinc-binding dehydrogenase 161 288 2.0E-23 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMALA_RS12145 683f562d156e7519ccbca9f5f795df70 339 Gene3D G3DSA:3.90.180.10 3 151 1.1E-41 T 29-03-2018 SMALA_RS34765 709719d2fc51d30ced4d73841ec9a7e5 132 SUPERFAMILY SSF54593 5 122 7.57E-11 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS34765 709719d2fc51d30ced4d73841ec9a7e5 132 Gene3D G3DSA:3.10.180.10 2 124 4.3E-19 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS24985 0bf845c71f5279bf1a504c14c7555821 400 Pfam PF01548 Transposase 11 166 2.3E-45 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 SMALA_RS24985 0bf845c71f5279bf1a504c14c7555821 400 Pfam PF02371 Transposase IS116/IS110/IS902 family 274 357 1.3E-23 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 SMALA_RS17280 6c3f8f59c065b50b224fc387b93f3d57 1068 Gene3D G3DSA:1.10.45.10 459 498 5.6E-8 T 29-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 SMALA_RS17280 6c3f8f59c065b50b224fc387b93f3d57 1068 Pfam PF02754 Cysteine-rich domain 846 921 0.0021 T 29-03-2018 IPR004017 Cysteine-rich domain SMALA_RS17280 6c3f8f59c065b50b224fc387b93f3d57 1068 Pfam PF13183 4Fe-4S dicluster domain 535 615 2.2E-9 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain SMALA_RS17280 6c3f8f59c065b50b224fc387b93f3d57 1068 Pfam PF02913 FAD linked oxidases, C-terminal domain 257 496 3.3E-45 T 29-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 SMALA_RS17280 6c3f8f59c065b50b224fc387b93f3d57 1068 Gene3D G3DSA:3.30.43.10 2 91 4.2E-22 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 SMALA_RS17280 6c3f8f59c065b50b224fc387b93f3d57 1068 Pfam PF01565 FAD binding domain 42 178 5.3E-40 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 SMALA_RS17280 6c3f8f59c065b50b224fc387b93f3d57 1068 Gene3D G3DSA:1.10.1060.10 518 636 1.0E-17 T 29-03-2018 SMALA_RS17280 6c3f8f59c065b50b224fc387b93f3d57 1068 SUPERFAMILY SSF46548 536 619 1.78E-7 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 SMALA_RS17280 6c3f8f59c065b50b224fc387b93f3d57 1068 SUPERFAMILY SSF56176 7 257 5.61E-61 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SMALA_RS17280 6c3f8f59c065b50b224fc387b93f3d57 1068 SUPERFAMILY SSF55103 232 498 7.52E-52 T 29-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 SMALA_RS17280 6c3f8f59c065b50b224fc387b93f3d57 1068 Gene3D G3DSA:3.30.465.10 92 279 3.5E-48 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SMALA_RS23580 b2b3c46837eecb8493f47174f3ea18d8 600 Pfam PF06276 Ferric iron reductase FhuF-like transporter 412 569 4.0E-41 T 29-03-2018 IPR022770 Ferric iron reductase FhuF domain SMALA_RS23580 b2b3c46837eecb8493f47174f3ea18d8 600 Pfam PF04183 IucA / IucC family 141 390 2.3E-77 T 29-03-2018 IPR007310 Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal GO:0015343|GO:0019290 SMALA_RS24475 7789d407b0382db102223fe78ca007d5 225 Pfam PF00440 Bacterial regulatory proteins, tetR family 41 86 2.6E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS24475 7789d407b0382db102223fe78ca007d5 225 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 62 85 1.9E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS24475 7789d407b0382db102223fe78ca007d5 225 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 54 1.9E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS24475 7789d407b0382db102223fe78ca007d5 225 SUPERFAMILY SSF48498 110 217 9.85E-15 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS24475 7789d407b0382db102223fe78ca007d5 225 Gene3D G3DSA:1.10.10.60 3 90 3.5E-17 T 29-03-2018 SMALA_RS24475 7789d407b0382db102223fe78ca007d5 225 SUPERFAMILY SSF46689 29 110 5.99E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS24475 7789d407b0382db102223fe78ca007d5 225 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 111 220 8.9E-24 T 29-03-2018 SMALA_RS24475 7789d407b0382db102223fe78ca007d5 225 Gene3D G3DSA:1.10.357.10 91 222 1.5E-19 T 29-03-2018 SMALA_RS11975 74d5a2432c81bc702dd549c115bef290 453 Gene3D G3DSA:3.30.565.10 265 445 1.5E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS11975 74d5a2432c81bc702dd549c115bef290 453 Pfam PF07730 Histidine kinase 238 303 2.8E-19 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMALA_RS11975 74d5a2432c81bc702dd549c115bef290 453 SUPERFAMILY SSF55874 340 444 6.02E-9 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS17095 04fcb63dffda70a64d00ea79be5ab6ea 192 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 24 172 1.8E-14 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS17095 04fcb63dffda70a64d00ea79be5ab6ea 192 Gene3D G3DSA:1.10.1740.10 12 84 8.9E-14 T 29-03-2018 SMALA_RS17095 04fcb63dffda70a64d00ea79be5ab6ea 192 Pfam PF04542 Sigma-70 region 2 28 94 5.7E-9 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS17095 04fcb63dffda70a64d00ea79be5ab6ea 192 Gene3D G3DSA:1.10.10.10 85 179 2.8E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS17095 04fcb63dffda70a64d00ea79be5ab6ea 192 SUPERFAMILY SSF88659 121 173 9.53E-7 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS17095 04fcb63dffda70a64d00ea79be5ab6ea 192 SUPERFAMILY SSF88946 10 104 1.22E-12 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS40345 687f431c358306506dfd686fd539ac3e 402 Gene3D G3DSA:3.40.50.10540 7 402 2.3E-140 T 29-03-2018 IPR023606 CoA-transferase family III domain SMALA_RS40345 687f431c358306506dfd686fd539ac3e 402 SUPERFAMILY SSF89796 11 402 9.55E-131 T 29-03-2018 IPR023606 CoA-transferase family III domain SMALA_RS40345 687f431c358306506dfd686fd539ac3e 402 Pfam PF02515 CoA-transferase family III 13 378 2.8E-129 T 29-03-2018 IPR003673 CoA-transferase family III GO:0003824 SMALA_RS40545 0460aed2f3bfa4ecafe95cb0a0c25ff8 259 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS40545 0460aed2f3bfa4ecafe95cb0a0c25ff8 259 SUPERFAMILY SSF52540 7 235 6.19E-65 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS40545 0460aed2f3bfa4ecafe95cb0a0c25ff8 259 SMART SM00382 36 217 1.8E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS40545 0460aed2f3bfa4ecafe95cb0a0c25ff8 259 Pfam PF00005 ABC transporter 27 166 7.3E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS40545 0460aed2f3bfa4ecafe95cb0a0c25ff8 259 Gene3D G3DSA:3.40.50.300 2 227 3.9E-61 T 29-03-2018 SMALA_RS14715 01c1c0d53f01f3497078157db15c4b22 263 Gene3D G3DSA:3.40.50.720 2 263 1.0E-41 T 29-03-2018 SMALA_RS14715 01c1c0d53f01f3497078157db15c4b22 263 SUPERFAMILY SSF51735 6 261 3.78E-48 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS14715 01c1c0d53f01f3497078157db15c4b22 263 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 259 1.4E-42 T 29-03-2018 SMALA_RS14715 01c1c0d53f01f3497078157db15c4b22 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 3.9E-16 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS14715 01c1c0d53f01f3497078157db15c4b22 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 189 206 3.9E-16 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS14715 01c1c0d53f01f3497078157db15c4b22 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 224 244 3.9E-16 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS14715 01c1c0d53f01f3497078157db15c4b22 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 187 3.9E-16 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS38120 8da6929fcb3206985d9c70b0f08fb772 610 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 536 5.9E-145 T 29-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 SMALA_RS38120 8da6929fcb3206985d9c70b0f08fb772 610 PIRSF PIRSF001589 1 604 3.6E-134 T 29-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 SMALA_RS38120 8da6929fcb3206985d9c70b0f08fb772 610 SUPERFAMILY SSF52402 228 396 5.59E-63 T 29-03-2018 SMALA_RS38120 8da6929fcb3206985d9c70b0f08fb772 610 SUPERFAMILY SSF52402 456 560 5.59E-63 T 29-03-2018 SMALA_RS38120 8da6929fcb3206985d9c70b0f08fb772 610 Pfam PF13537 Glutamine amidotransferase domain 48 169 1.3E-44 T 29-03-2018 IPR017932 Glutamine amidotransferase type 2 domain SMALA_RS38120 8da6929fcb3206985d9c70b0f08fb772 610 SUPERFAMILY SSF56235 2 224 5.49E-61 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SMALA_RS38120 8da6929fcb3206985d9c70b0f08fb772 610 Gene3D G3DSA:3.40.50.620 222 605 1.3E-62 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS38120 8da6929fcb3206985d9c70b0f08fb772 610 Gene3D G3DSA:3.60.20.10 1 221 4.8E-56 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SMALA_RS38120 8da6929fcb3206985d9c70b0f08fb772 610 Pfam PF00733 Asparagine synthase 240 600 3.9E-82 T 29-03-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 SMALA_RS36290 9ab96f5ad411b0d3fc11d569866276e2 601 Gene3D G3DSA:2.160.20.10 311 558 1.9E-28 T 29-03-2018 IPR012334 Pectin lyase fold SMALA_RS19945 0731f72a7d0a93550602cfaa7dc6141d 253 SUPERFAMILY SSF75217 104 246 1.64E-27 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases SMALA_RS19945 0731f72a7d0a93550602cfaa7dc6141d 253 Gene3D G3DSA:3.40.1280.10 103 248 4.3E-28 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal SMALA_RS19945 0731f72a7d0a93550602cfaa7dc6141d 253 Pfam PF00588 SpoU rRNA Methylase family 114 243 1.3E-23 T 29-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 SMALA_RS39580 a17d1168ece681ebbab191c3191c3625 254 Pfam PF02665 Nitrate reductase gamma subunit 14 232 6.2E-82 T 29-03-2018 IPR023234 NarG-like domain SMALA_RS39580 a17d1168ece681ebbab191c3191c3625 254 SUPERFAMILY SSF103501 12 232 5.62E-66 T 29-03-2018 IPR023234 NarG-like domain SMALA_RS39580 a17d1168ece681ebbab191c3191c3625 254 Gene3D G3DSA:1.20.950.20 11 224 2.2E-45 T 29-03-2018 SMALA_RS39580 a17d1168ece681ebbab191c3191c3625 254 TIGRFAM TIGR00351 narI: respiratory nitrate reductase, gamma subunit 12 232 8.8E-60 T 29-03-2018 IPR003816 Nitrate reductase, gamma subunit GO:0008940|GO:0009325|GO:0055114 KEGG: 00910+1.7.99.4 SMALA_RS40415 b0d05a6b411a660a3a42a0fd056a38c8 340 Pfam PF13407 Periplasmic binding protein domain 39 305 2.0E-36 T 29-03-2018 IPR025997 Periplasmic binding protein SMALA_RS40415 b0d05a6b411a660a3a42a0fd056a38c8 340 SUPERFAMILY SSF53822 37 317 1.45E-43 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SMALA_RS40415 b0d05a6b411a660a3a42a0fd056a38c8 340 Gene3D G3DSA:3.40.50.2300 160 318 1.6E-24 T 29-03-2018 SMALA_RS40415 b0d05a6b411a660a3a42a0fd056a38c8 340 Gene3D G3DSA:3.40.50.2300 35 159 6.0E-15 T 29-03-2018 SMALA_RS30580 90930439c25180d6411ee225ee9c3ec3 276 Gene3D G3DSA:3.60.160.10 1 269 2.5E-53 T 29-03-2018 IPR002838 Mitochondrial biogenesis protein AIM24 SMALA_RS30580 90930439c25180d6411ee225ee9c3ec3 276 SUPERFAMILY SSF51219 4 258 2.88E-47 T 29-03-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain SMALA_RS30580 90930439c25180d6411ee225ee9c3ec3 276 Pfam PF01987 Mitochondrial biogenesis AIM24 6 245 5.7E-51 T 29-03-2018 IPR002838 Mitochondrial biogenesis protein AIM24 SMALA_RS42865 1a6c989f497b2465c22ffc08f5de4c4e 208 Gene3D G3DSA:3.50.30.40 10 193 8.4E-34 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein SMALA_RS42865 1a6c989f497b2465c22ffc08f5de4c4e 208 SUPERFAMILY SSF89562 11 184 2.49E-26 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein SMALA_RS42865 1a6c989f497b2465c22ffc08f5de4c4e 208 Pfam PF03737 Aldolase/RraA 15 173 1.5E-27 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein SMALA_RS39520 6df26e496e52608e92f90183bc46060b 595 SUPERFAMILY SSF90123 23 336 2.22E-57 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMALA_RS39520 6df26e496e52608e92f90183bc46060b 595 SUPERFAMILY SSF52540 350 590 4.39E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS39520 6df26e496e52608e92f90183bc46060b 595 Pfam PF00005 ABC transporter 372 521 1.3E-17 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS39520 6df26e496e52608e92f90183bc46060b 595 Gene3D G3DSA:3.40.50.300 348 593 2.2E-46 T 29-03-2018 SMALA_RS39520 6df26e496e52608e92f90183bc46060b 595 Pfam PF00664 ABC transporter transmembrane region 36 307 1.7E-35 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMALA_RS39520 6df26e496e52608e92f90183bc46060b 595 Gene3D G3DSA:1.20.1560.10 19 337 1.1E-48 T 29-03-2018 SMALA_RS39520 6df26e496e52608e92f90183bc46060b 595 SMART SM00382 381 567 2.5E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS09465 582eb8031eb51a1280a1bd54a4e1c77e 254 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 4 245 1.1E-102 T 29-03-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524|GO:0006810 SMALA_RS09465 582eb8031eb51a1280a1bd54a4e1c77e 254 Gene3D G3DSA:3.40.50.300 1 253 2.1E-41 T 29-03-2018 SMALA_RS09465 582eb8031eb51a1280a1bd54a4e1c77e 254 Pfam PF00005 ABC transporter 23 174 3.9E-21 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS09465 582eb8031eb51a1280a1bd54a4e1c77e 254 SUPERFAMILY SSF52540 4 234 1.03E-41 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS09465 582eb8031eb51a1280a1bd54a4e1c77e 254 SMART SM00382 32 225 1.4E-4 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS22170 19f0b489ec489ef5c6c076a59dba6292 550 Pfam PF00361 Proton-conducting membrane transporter 180 485 2.1E-72 T 29-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS22170 19f0b489ec489ef5c6c076a59dba6292 550 TIGRFAM TIGR01770 NDH_I_N: proton-translocating NADH-quinone oxidoreductase, chain N 154 538 4.5E-115 T 29-03-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 SMALA_RS22170 19f0b489ec489ef5c6c076a59dba6292 550 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 26 539 17.931 T 29-03-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 SMALA_RS14790 8b63f19712f06e87f61dfe132b855eaa 304 SMART SM00421 236 293 0.0029 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS14790 8b63f19712f06e87f61dfe132b855eaa 304 SUPERFAMILY SSF46894 241 299 4.08E-7 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS14790 8b63f19712f06e87f61dfe132b855eaa 304 Gene3D G3DSA:1.10.10.10 155 298 8.8E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS25840 fe76af71b760f6b2f47771c455a1e2c8 384 Pfam PF01883 Iron-sulfur cluster assembly protein 11 83 3.4E-18 T 29-03-2018 IPR002744 MIP18 family-like SMALA_RS25840 fe76af71b760f6b2f47771c455a1e2c8 384 Hamap MF_02040 Iron-sulfur cluster carrier protein. 109 365 34.854 T 29-03-2018 IPR019591 Mrp/NBP35 ATP-binding protein SMALA_RS25840 fe76af71b760f6b2f47771c455a1e2c8 384 Gene3D G3DSA:3.30.300.130 8 94 1.5E-18 T 29-03-2018 IPR034904 Fe-S cluster assembly domain SMALA_RS25840 fe76af71b760f6b2f47771c455a1e2c8 384 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 118 364 7.8E-92 T 29-03-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 SMALA_RS25840 fe76af71b760f6b2f47771c455a1e2c8 384 Gene3D G3DSA:3.40.50.300 95 373 4.4E-59 T 29-03-2018 SMALA_RS25840 fe76af71b760f6b2f47771c455a1e2c8 384 SUPERFAMILY SSF117916 9 93 5.23E-23 T 29-03-2018 IPR034904 Fe-S cluster assembly domain SMALA_RS25840 fe76af71b760f6b2f47771c455a1e2c8 384 SUPERFAMILY SSF52540 118 367 2.19E-53 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS25840 fe76af71b760f6b2f47771c455a1e2c8 384 ProSitePatterns PS01215 Mrp family signature. 222 238 - T 29-03-2018 IPR000808 Mrp, conserved site GO:0005524 SMALA_RS15335 01678f8fa85e2a15f8972b49c96be1c8 445 Gene3D G3DSA:3.40.190.10 49 182 3.0E-21 T 29-03-2018 SMALA_RS15335 01678f8fa85e2a15f8972b49c96be1c8 445 Gene3D G3DSA:3.40.190.10 183 445 5.2E-41 T 29-03-2018 SMALA_RS15335 01678f8fa85e2a15f8972b49c96be1c8 445 SUPERFAMILY SSF53850 50 440 2.33E-77 T 29-03-2018 SMALA_RS15335 01678f8fa85e2a15f8972b49c96be1c8 445 Pfam PF13416 Bacterial extracellular solute-binding protein 71 379 7.5E-37 T 29-03-2018 SMALA_RS12135 f46b712b68d4516f2a9157af27582a8a 333 SUPERFAMILY SSF51126 48 332 1.71E-75 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor SMALA_RS12135 f46b712b68d4516f2a9157af27582a8a 333 Pfam PF00544 Pectate lyase 96 266 1.2E-42 T 29-03-2018 IPR002022 Pectate lyase SMALA_RS12135 f46b712b68d4516f2a9157af27582a8a 333 Gene3D G3DSA:2.160.20.10 28 94 1.5E-10 T 29-03-2018 IPR012334 Pectin lyase fold SMALA_RS12135 f46b712b68d4516f2a9157af27582a8a 333 SMART SM00656 60 272 1.7E-37 T 29-03-2018 IPR002022 Pectate lyase SMALA_RS12135 f46b712b68d4516f2a9157af27582a8a 333 Gene3D G3DSA:2.160.20.10 95 333 1.8E-60 T 29-03-2018 IPR012334 Pectin lyase fold SMALA_RS31295 93cf03ee5557d60fcdc8e8fbe468ba99 194 SUPERFAMILY SSF46689 2 80 4.67E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS31295 93cf03ee5557d60fcdc8e8fbe468ba99 194 SUPERFAMILY SSF48498 78 193 4.45E-26 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS31295 93cf03ee5557d60fcdc8e8fbe468ba99 194 Gene3D G3DSA:1.10.357.10 59 194 2.4E-27 T 29-03-2018 SMALA_RS31295 93cf03ee5557d60fcdc8e8fbe468ba99 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 56 8.5E-14 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS31295 93cf03ee5557d60fcdc8e8fbe468ba99 194 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 107 192 4.5E-7 T 29-03-2018 SMALA_RS31295 93cf03ee5557d60fcdc8e8fbe468ba99 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 6.5E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS31295 93cf03ee5557d60fcdc8e8fbe468ba99 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 6.5E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS31295 93cf03ee5557d60fcdc8e8fbe468ba99 194 Gene3D G3DSA:1.10.10.60 1 58 8.7E-17 T 29-03-2018 SMALA_RS23455 8f0c42c1fb3f4d5e69f8e1049c204614 432 SUPERFAMILY SSF53850 80 347 8.58E-47 T 29-03-2018 SMALA_RS23455 8f0c42c1fb3f4d5e69f8e1049c204614 432 Pfam PF01547 Bacterial extracellular solute-binding protein 78 343 7.4E-29 T 29-03-2018 IPR006059 Solute-binding family 1 GO:0006810 SMALA_RS23455 8f0c42c1fb3f4d5e69f8e1049c204614 432 Gene3D G3DSA:3.40.190.10 159 351 9.7E-34 T 29-03-2018 SMALA_RS40825 37098cfb4383f234386a242d1456261f 351 SUPERFAMILY SSF51556 8 46 1.24E-76 T 29-03-2018 IPR032466 Metal-dependent hydrolase SMALA_RS40825 37098cfb4383f234386a242d1456261f 351 SUPERFAMILY SSF51556 73 346 1.24E-76 T 29-03-2018 IPR032466 Metal-dependent hydrolase SMALA_RS40825 37098cfb4383f234386a242d1456261f 351 ProSitePatterns PS01322 Phosphotriesterase family signature 1. 22 30 - T 29-03-2018 IPR017947 Aryldialkylphosphatase, zinc-binding site GO:0008270|GO:0009056|GO:0016788 SMALA_RS40825 37098cfb4383f234386a242d1456261f 351 Gene3D G3DSA:3.20.20.140 5 350 2.4E-61 T 29-03-2018 SMALA_RS40825 37098cfb4383f234386a242d1456261f 351 Pfam PF02126 Phosphotriesterase family 20 346 5.4E-47 T 29-03-2018 IPR001559 Phosphotriesterase GO:0008270|GO:0009056 SMALA_RS06025 d66cf67c8ea4c188faffdcf158915bcd 261 Pfam PF03649 Uncharacterised protein family (UPF0014) 18 251 5.1E-42 T 29-03-2018 IPR005226 UPF0014 family SMALA_RS41045 c1c43a1dfed4db0bf939c152159ed5fc 447 Gene3D G3DSA:3.40.190.10 160 447 1.4E-43 T 29-03-2018 SMALA_RS41045 c1c43a1dfed4db0bf939c152159ed5fc 447 SUPERFAMILY SSF53850 62 440 8.28E-61 T 29-03-2018 SMALA_RS41045 c1c43a1dfed4db0bf939c152159ed5fc 447 Pfam PF13416 Bacterial extracellular solute-binding protein 71 369 2.2E-38 T 29-03-2018 SMALA_RS25415 364e073ff8bfa7db3228ab27381b0037 447 SUPERFAMILY SSF54060 249 292 1.53E-9 T 29-03-2018 SMALA_RS25415 364e073ff8bfa7db3228ab27381b0037 447 Pfam PF02945 Recombination endonuclease VII 249 285 2.8E-9 T 29-03-2018 IPR004211 Recombination endonuclease VII SMALA_RS42220 d899c03e9e7f85028152b2deb41d77b5 406 Gene3D G3DSA:1.20.1250.20 200 401 2.7E-12 T 29-03-2018 SMALA_RS42220 d899c03e9e7f85028152b2deb41d77b5 406 Gene3D G3DSA:1.20.1250.20 10 197 3.4E-16 T 29-03-2018 SMALA_RS42220 d899c03e9e7f85028152b2deb41d77b5 406 SUPERFAMILY SSF103473 15 399 4.32E-34 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS42220 d899c03e9e7f85028152b2deb41d77b5 406 Pfam PF07690 Major Facilitator Superfamily 16 215 1.4E-17 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS23385 22e00e17573d97535fa171c4a80fcdb7 568 Gene3D G3DSA:1.10.510.10 118 296 2.5E-46 T 29-03-2018 SMALA_RS23385 22e00e17573d97535fa171c4a80fcdb7 568 Gene3D G3DSA:2.60.120.430 441 567 5.4E-21 T 29-03-2018 SMALA_RS23385 22e00e17573d97535fa171c4a80fcdb7 568 SMART SM00220 34 289 5.3E-58 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMALA_RS23385 22e00e17573d97535fa171c4a80fcdb7 568 SUPERFAMILY SSF56112 26 305 7.59E-68 T 29-03-2018 IPR011009 Protein kinase-like domain SMALA_RS23385 22e00e17573d97535fa171c4a80fcdb7 568 Gene3D G3DSA:3.30.200.20 27 117 1.1E-22 T 29-03-2018 SMALA_RS23385 22e00e17573d97535fa171c4a80fcdb7 568 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 40 63 - T 29-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 SMALA_RS23385 22e00e17573d97535fa171c4a80fcdb7 568 Pfam PF00069 Protein kinase domain 34 281 3.5E-48 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMALA_RS25345 f94bbbab65c7aa10d3087d9999f609f2 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 1.3E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS25345 f94bbbab65c7aa10d3087d9999f609f2 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 1.3E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS25345 f94bbbab65c7aa10d3087d9999f609f2 206 SUPERFAMILY SSF46689 3 74 2.62E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS25345 f94bbbab65c7aa10d3087d9999f609f2 206 Gene3D G3DSA:1.10.10.60 1 55 5.0E-15 T 29-03-2018 SMALA_RS25345 f94bbbab65c7aa10d3087d9999f609f2 206 Gene3D G3DSA:1.10.357.10 56 199 1.5E-13 T 29-03-2018 SMALA_RS25345 f94bbbab65c7aa10d3087d9999f609f2 206 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 57 9.0E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS21470 3f74b586c82d761cd55bf7c659358455 187 Hamap MF_01297 UPF0678 fatty acid-binding protein-like protein . 4 166 31.668 T 29-03-2018 IPR022939 Uncharacterised protein family UPF0678 SMALA_RS21470 3f74b586c82d761cd55bf7c659358455 187 Gene3D G3DSA:2.40.128.20 1 167 8.5E-59 T 29-03-2018 IPR012674 Calycin SMALA_RS21470 3f74b586c82d761cd55bf7c659358455 187 Pfam PF08768 Domain of unknown function (DUF1794) 12 164 1.3E-46 T 29-03-2018 IPR014878 Domain of unknown function DUF1794 SMALA_RS21470 3f74b586c82d761cd55bf7c659358455 187 SUPERFAMILY SSF50814 7 165 2.12E-40 T 29-03-2018 IPR012674 Calycin SMALA_RS37235 e460da361233629c6ab7ec28f96c78c5 571 Pfam PF13556 PucR C-terminal helix-turn-helix domain 500 557 9.4E-15 T 29-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain SMALA_RS37235 e460da361233629c6ab7ec28f96c78c5 571 Gene3D G3DSA:3.40.50.2300 331 488 0.15 T 29-03-2018 SMALA_RS37235 e460da361233629c6ab7ec28f96c78c5 571 Gene3D G3DSA:1.10.10.60 489 536 0.0019 T 29-03-2018 SMALA_RS37235 e460da361233629c6ab7ec28f96c78c5 571 Pfam PF07905 Purine catabolism regulatory protein-like family 45 166 6.6E-35 T 29-03-2018 IPR012914 Purine catabolism PurC-like domain SMALA_RS37235 e460da361233629c6ab7ec28f96c78c5 571 Gene3D G3DSA:3.40.50.2300 82 299 0.015 T 29-03-2018 SMALA_RS33285 11525701593c21226940386b7aa9f81b 434 SUPERFAMILY SSF48230 97 379 6.41E-58 T 29-03-2018 IPR008929 Chondroitin AC/alginate lyase Reactome: R-HSA-2022923 SMALA_RS33285 11525701593c21226940386b7aa9f81b 434 Pfam PF05426 Alginate lyase 92 376 1.2E-90 T 29-03-2018 IPR008397 Alginate lyase domain GO:0016829|GO:0042597 KEGG: 00051+4.2.2.3|MetaCyc: PWY-6986 SMALA_RS33285 11525701593c21226940386b7aa9f81b 434 Gene3D G3DSA:1.50.10.100 93 408 2.1E-56 T 29-03-2018 SMALA_RS15660 e7d89f1357bcdcb569375aa0894a9211 249 Pfam PF00072 Response regulator receiver domain 35 146 2.0E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS15660 e7d89f1357bcdcb569375aa0894a9211 249 SMART SM00421 183 240 3.2E-28 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS15660 e7d89f1357bcdcb569375aa0894a9211 249 Gene3D G3DSA:1.10.10.10 158 249 1.0E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS15660 e7d89f1357bcdcb569375aa0894a9211 249 Pfam PF00196 Bacterial regulatory proteins, luxR family 185 240 3.3E-23 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS15660 e7d89f1357bcdcb569375aa0894a9211 249 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 216 228 7.9E-16 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS15660 e7d89f1357bcdcb569375aa0894a9211 249 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 186 200 7.9E-16 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS15660 e7d89f1357bcdcb569375aa0894a9211 249 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 200 216 7.9E-16 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS15660 e7d89f1357bcdcb569375aa0894a9211 249 SMART SM00448 33 146 1.3E-32 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS15660 e7d89f1357bcdcb569375aa0894a9211 249 ProSitePatterns PS00622 LuxR-type HTH domain signature. 200 227 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS15660 e7d89f1357bcdcb569375aa0894a9211 249 SUPERFAMILY SSF46894 169 246 3.74E-24 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS15660 e7d89f1357bcdcb569375aa0894a9211 249 Gene3D G3DSA:3.40.50.2300 32 157 3.8E-37 T 29-03-2018 SMALA_RS15660 e7d89f1357bcdcb569375aa0894a9211 249 SUPERFAMILY SSF52172 32 162 3.84E-36 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS13515 48a1b77e4c33deb3ec09c4efe4018c35 554 Pfam PF00005 ABC transporter 338 471 1.4E-20 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS13515 48a1b77e4c33deb3ec09c4efe4018c35 554 Pfam PF00005 ABC transporter 21 188 1.1E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS13515 48a1b77e4c33deb3ec09c4efe4018c35 554 Gene3D G3DSA:3.40.50.300 288 549 3.3E-51 T 29-03-2018 SMALA_RS13515 48a1b77e4c33deb3ec09c4efe4018c35 554 Pfam PF12848 ABC transporter 227 305 5.0E-12 T 29-03-2018 IPR032781 ABC-transporter extension domain SMALA_RS13515 48a1b77e4c33deb3ec09c4efe4018c35 554 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS13515 48a1b77e4c33deb3ec09c4efe4018c35 554 Gene3D G3DSA:3.40.50.300 3 287 3.1E-56 T 29-03-2018 SMALA_RS13515 48a1b77e4c33deb3ec09c4efe4018c35 554 SMART SM00382 346 516 4.7E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS13515 48a1b77e4c33deb3ec09c4efe4018c35 554 SMART SM00382 30 239 1.4E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS13515 48a1b77e4c33deb3ec09c4efe4018c35 554 TIGRFAM TIGR03719 ABC_ABC_ChvD: ATP-binding cassette protein, ChvD family 3 551 2.6E-273 T 29-03-2018 IPR022374 ABC transporter, ATP-binding protein, ChvD SMALA_RS13515 48a1b77e4c33deb3ec09c4efe4018c35 554 SUPERFAMILY SSF52540 13 240 8.63E-50 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS13515 48a1b77e4c33deb3ec09c4efe4018c35 554 SUPERFAMILY SSF52540 306 515 1.67E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS13515 48a1b77e4c33deb3ec09c4efe4018c35 554 ProSitePatterns PS00211 ABC transporters family signature. 443 457 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS06135 697eef918891b0f7e9302f54f007ab05 248 Pfam PF12697 Alpha/beta hydrolase family 1 238 2.4E-22 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS06135 697eef918891b0f7e9302f54f007ab05 248 SUPERFAMILY SSF53474 1 246 1.51E-47 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS06135 697eef918891b0f7e9302f54f007ab05 248 PRINTS PR00111 Alpha/beta hydrolase fold signature 81 94 1.8E-12 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS06135 697eef918891b0f7e9302f54f007ab05 248 PRINTS PR00111 Alpha/beta hydrolase fold signature 192 206 1.8E-12 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS06135 697eef918891b0f7e9302f54f007ab05 248 PRINTS PR00111 Alpha/beta hydrolase fold signature 95 108 1.8E-12 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS06135 697eef918891b0f7e9302f54f007ab05 248 PRINTS PR00111 Alpha/beta hydrolase fold signature 27 42 1.8E-12 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS06135 697eef918891b0f7e9302f54f007ab05 248 Gene3D G3DSA:3.40.50.1820 1 248 7.9E-41 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS01500 d12180eccffec6f58425f6420e54535e 202 Gene3D G3DSA:1.10.357.10 5 202 2.3E-21 T 29-03-2018 SMALA_RS01500 d12180eccffec6f58425f6420e54535e 202 SUPERFAMILY SSF46689 2 81 1.8E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS01500 d12180eccffec6f58425f6420e54535e 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 57 3.4E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS31815 ee40430c9e586900431d4394d719d922 283 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 100 278 5.4E-24 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS31815 ee40430c9e586900431d4394d719d922 283 SUPERFAMILY SSF161098 77 256 3.92E-21 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS31815 ee40430c9e586900431d4394d719d922 283 Gene3D G3DSA:1.10.3720.10 12 274 1.5E-33 T 29-03-2018 SMALA_RS35275 fa44a0e47999968a7823882689adcc3f 381 SUPERFAMILY SSF51735 152 340 1.28E-66 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS35275 fa44a0e47999968a7823882689adcc3f 381 Gene3D G3DSA:3.40.50.720 172 322 3.3E-22 T 29-03-2018 SMALA_RS35275 fa44a0e47999968a7823882689adcc3f 381 Pfam PF13823 Alcohol dehydrogenase GroES-associated 2 23 1.8E-6 T 29-03-2018 IPR027399 Alcohol dehydrogenase GroES-associated SMALA_RS35275 fa44a0e47999968a7823882689adcc3f 381 Pfam PF00107 Zinc-binding dehydrogenase 185 255 5.6E-10 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMALA_RS35275 fa44a0e47999968a7823882689adcc3f 381 Gene3D G3DSA:3.90.180.10 1 171 1.8E-42 T 29-03-2018 SMALA_RS35275 fa44a0e47999968a7823882689adcc3f 381 SUPERFAMILY SSF50129 2 185 5.02E-60 T 29-03-2018 IPR011032 GroES-like SMALA_RS35275 fa44a0e47999968a7823882689adcc3f 381 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 137 3.9E-27 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS17055 9530e6ed59c38b155e824b62df3d4490 610 SMART SM00220 117 374 5.7E-60 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMALA_RS17055 9530e6ed59c38b155e824b62df3d4490 610 Gene3D G3DSA:1.10.510.10 203 557 1.6E-50 T 29-03-2018 SMALA_RS17055 9530e6ed59c38b155e824b62df3d4490 610 Pfam PF00069 Protein kinase domain 117 369 7.1E-46 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMALA_RS17055 9530e6ed59c38b155e824b62df3d4490 610 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 123 146 - T 29-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 SMALA_RS17055 9530e6ed59c38b155e824b62df3d4490 610 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 239 251 - T 29-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMALA_RS17055 9530e6ed59c38b155e824b62df3d4490 610 Gene3D G3DSA:3.30.200.20 96 202 1.7E-20 T 29-03-2018 SMALA_RS17055 9530e6ed59c38b155e824b62df3d4490 610 SUPERFAMILY SSF56112 109 377 4.13E-69 T 29-03-2018 IPR011009 Protein kinase-like domain SMALA_RS32585 d8a83a85bbbc985aa59ca000d5daada7 1519 Pfam PF02277 Phosphoribosyltransferase 1178 1515 6.3E-125 T 29-03-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 SMALA_RS32585 d8a83a85bbbc985aa59ca000d5daada7 1519 TIGRFAM TIGR02476 BluB: 5,6-dimethylbenzimidazole synthase 948 1153 1.3E-91 T 29-03-2018 IPR012825 5,6-dimethylbenzimidazole synthase BluB KEGG: 00740+1.13.11.79|MetaCyc: PWY-5508|MetaCyc: PWY-5523 SMALA_RS32585 d8a83a85bbbc985aa59ca000d5daada7 1519 Gene3D G3DSA:3.40.109.10 945 1162 1.9E-45 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMALA_RS32585 d8a83a85bbbc985aa59ca000d5daada7 1519 Gene3D G3DSA:1.10.1610.10 1172 1239 4.7E-26 T 29-03-2018 IPR023195 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 SMALA_RS32585 d8a83a85bbbc985aa59ca000d5daada7 1519 Pfam PF00881 Nitroreductase family 960 1127 2.3E-31 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 SMALA_RS32585 d8a83a85bbbc985aa59ca000d5daada7 1519 SUPERFAMILY SSF55469 956 1160 3.4E-52 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMALA_RS32585 d8a83a85bbbc985aa59ca000d5daada7 1519 SUPERFAMILY SSF52733 1172 1516 2.75E-113 T 29-03-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 SMALA_RS32585 d8a83a85bbbc985aa59ca000d5daada7 1519 Gene3D G3DSA:3.40.50.10210 1240 1498 5.4E-105 T 29-03-2018 SMALA_RS32585 d8a83a85bbbc985aa59ca000d5daada7 1519 Hamap MF_00230 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase [cobT]. 1180 1517 34.682 T 29-03-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 SMALA_RS32585 d8a83a85bbbc985aa59ca000d5daada7 1519 TIGRFAM TIGR03160 cobT_DBIPRT: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 1182 1515 4.3E-124 T 29-03-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 SMALA_RS36935 0a447afec5697277f77872f200f759e0 253 Pfam PF12730 ABC-2 family transporter protein 3 174 1.6E-7 T 29-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 SMALA_RS16640 4bc572a8a4f50ff17327f3e295fc84e1 237 SUPERFAMILY SSF56037 61 225 2.35E-24 T 29-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 SMALA_RS16640 4bc572a8a4f50ff17327f3e295fc84e1 237 Gene3D G3DSA:3.50.40.10 68 210 4.9E-21 T 29-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 SMALA_RS16640 4bc572a8a4f50ff17327f3e295fc84e1 237 SMART SM00873 71 225 6.4E-10 T 29-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 SMALA_RS16640 4bc572a8a4f50ff17327f3e295fc84e1 237 Pfam PF03483 B3/4 domain 72 204 1.6E-16 T 29-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 SMALA_RS41140 245f4c0ec29a273547bc3e99f26a0a96 277 SUPERFAMILY SSF161098 3 277 8.5E-63 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS41140 245f4c0ec29a273547bc3e99f26a0a96 277 Gene3D G3DSA:1.10.3720.10 2 264 6.1E-43 T 29-03-2018 SMALA_RS41140 245f4c0ec29a273547bc3e99f26a0a96 277 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 263 3.5E-22 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS26705 fbfadeb3c4697a659bac79aac615b6cf 196 SUPERFAMILY SSF81296 11 196 2.94E-33 T 29-03-2018 IPR014756 Immunoglobulin E-set SMALA_RS26705 fbfadeb3c4697a659bac79aac615b6cf 196 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 11 193 9.8E-34 T 29-03-2018 IPR004302 Cellulose/chitin-binding protein, N-terminal SMALA_RS26705 fbfadeb3c4697a659bac79aac615b6cf 196 Gene3D G3DSA:2.70.50.50 11 196 1.5E-52 T 29-03-2018 SMALA_RS26255 ba4b6ff520ffb6be599e1ed87e87d21f 164 Pfam PF01047 MarR family 46 99 4.8E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS26255 ba4b6ff520ffb6be599e1ed87e87d21f 164 ProSitePatterns PS01117 MarR-type HTH domain signature. 74 108 - T 29-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site SMALA_RS26255 ba4b6ff520ffb6be599e1ed87e87d21f 164 SMART SM00347 35 135 1.8E-15 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS26255 ba4b6ff520ffb6be599e1ed87e87d21f 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 59 75 4.3E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS26255 ba4b6ff520ffb6be599e1ed87e87d21f 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 95 111 4.3E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS26255 ba4b6ff520ffb6be599e1ed87e87d21f 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 76 91 4.3E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS26255 ba4b6ff520ffb6be599e1ed87e87d21f 164 SUPERFAMILY SSF46785 17 150 2.0E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS26255 ba4b6ff520ffb6be599e1ed87e87d21f 164 Gene3D G3DSA:1.10.10.10 4 149 1.7E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS22770 9a43971b65f168548990ff0c909a4d99 122 SUPERFAMILY SSF56214 2 121 5.62E-24 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 SMALA_RS22770 9a43971b65f168548990ff0c909a4d99 122 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 3 120 3.2E-22 T 29-03-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 SMALA_RS22770 9a43971b65f168548990ff0c909a4d99 122 TIGRFAM TIGR00516 acpS: holo-[acyl-carrier-protein] synthase 2 121 4.6E-20 T 29-03-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 SMALA_RS22770 9a43971b65f168548990ff0c909a4d99 122 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 3 122 21.51 T 29-03-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 SMALA_RS22770 9a43971b65f168548990ff0c909a4d99 122 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 8 83 1.0E-12 T 29-03-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 SMALA_RS22770 9a43971b65f168548990ff0c909a4d99 122 Gene3D G3DSA:3.90.470.20 1 122 1.3E-27 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 SMALA_RS22770 9a43971b65f168548990ff0c909a4d99 122 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 4 104 1.5E-12 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 SMALA_RS13870 74a779d22c6985fcb8f4a954516486e1 310 Pfam PF04962 KduI/IolB family 12 286 2.5E-85 T 29-03-2018 IPR021120 KduI/IolB isomerase GO:0016861 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 SMALA_RS13870 74a779d22c6985fcb8f4a954516486e1 310 Gene3D G3DSA:2.60.120.10 127 291 3.7E-63 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SMALA_RS13870 74a779d22c6985fcb8f4a954516486e1 310 TIGRFAM TIGR04378 myo_inos_iolB: 5-deoxy-glucuronate isomerase 25 287 1.7E-81 T 29-03-2018 IPR024203 5-deoxy-glucuronate isomerase, IolB GO:0008880|GO:0019310 KEGG: 00562+5.3.1.30 SMALA_RS13870 74a779d22c6985fcb8f4a954516486e1 310 PIRSF PIRSF036628 10 292 2.1E-98 T 29-03-2018 IPR024203 5-deoxy-glucuronate isomerase, IolB GO:0008880|GO:0019310 KEGG: 00562+5.3.1.30 SMALA_RS13870 74a779d22c6985fcb8f4a954516486e1 310 Gene3D G3DSA:2.60.120.10 23 126 7.4E-41 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SMALA_RS13870 74a779d22c6985fcb8f4a954516486e1 310 SUPERFAMILY SSF51182 22 275 1.9E-57 T 29-03-2018 IPR011051 RmlC-like cupin domain SMALA_RS34440 5b1b5ba9f18dbcc90d2272b6f1e2528e 190 Gene3D G3DSA:2.60.120.10 82 189 2.1E-18 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SMALA_RS34440 5b1b5ba9f18dbcc90d2272b6f1e2528e 190 SUPERFAMILY SSF47413 8 74 3.75E-18 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS34440 5b1b5ba9f18dbcc90d2272b6f1e2528e 190 SMART SM00530 14 69 2.4E-15 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS34440 5b1b5ba9f18dbcc90d2272b6f1e2528e 190 SUPERFAMILY SSF51182 57 185 9.44E-25 T 29-03-2018 IPR011051 RmlC-like cupin domain SMALA_RS34440 5b1b5ba9f18dbcc90d2272b6f1e2528e 190 Gene3D G3DSA:1.10.260.40 2 62 1.8E-19 T 29-03-2018 SMALA_RS34440 5b1b5ba9f18dbcc90d2272b6f1e2528e 190 Pfam PF07883 Cupin domain 114 182 2.5E-15 T 29-03-2018 IPR013096 Cupin 2, conserved barrel SMALA_RS34440 5b1b5ba9f18dbcc90d2272b6f1e2528e 190 Gene3D G3DSA:1.10.260.40 63 81 0.088 T 29-03-2018 SMALA_RS34440 5b1b5ba9f18dbcc90d2272b6f1e2528e 190 Pfam PF01381 Helix-turn-helix 15 68 3.8E-13 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS01695 aac8a818221b1fb5b52820c72c1e9b92 464 Gene3D G3DSA:3.30.9.10 233 358 2.7E-17 T 29-03-2018 SMALA_RS01695 aac8a818221b1fb5b52820c72c1e9b92 464 Gene3D G3DSA:3.50.50.60 6 232 5.3E-15 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS01695 aac8a818221b1fb5b52820c72c1e9b92 464 Pfam PF01266 FAD dependent oxidoreductase 37 398 2.9E-51 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 SMALA_RS01695 aac8a818221b1fb5b52820c72c1e9b92 464 SUPERFAMILY SSF51905 22 131 1.09E-38 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS01695 aac8a818221b1fb5b52820c72c1e9b92 464 SUPERFAMILY SSF51905 186 312 1.09E-38 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS10040 83c78227f024cdb737cd840a29e822f4 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 3.4E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS10040 83c78227f024cdb737cd840a29e822f4 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 3.4E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS10040 83c78227f024cdb737cd840a29e822f4 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 3.4E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS10040 83c78227f024cdb737cd840a29e822f4 247 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 189 8.5E-4 T 29-03-2018 SMALA_RS10040 83c78227f024cdb737cd840a29e822f4 247 SUPERFAMILY SSF51735 7 232 7.25E-68 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS10040 83c78227f024cdb737cd840a29e822f4 247 Gene3D G3DSA:3.40.50.720 1 199 7.2E-61 T 29-03-2018 SMALA_RS10040 83c78227f024cdb737cd840a29e822f4 247 Pfam PF00106 short chain dehydrogenase 9 199 4.8E-55 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS10040 83c78227f024cdb737cd840a29e822f4 247 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMALA_RS10040 83c78227f024cdb737cd840a29e822f4 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 4.8E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS10040 83c78227f024cdb737cd840a29e822f4 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 4.8E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS10040 83c78227f024cdb737cd840a29e822f4 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 4.8E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS10040 83c78227f024cdb737cd840a29e822f4 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 4.8E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS10040 83c78227f024cdb737cd840a29e822f4 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 4.8E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS33280 30249904e858b5799e1774ca096b38d4 408 Gene3D G3DSA:1.10.10.10 16 82 7.1E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS33280 30249904e858b5799e1774ca096b38d4 408 Gene3D G3DSA:3.30.420.40 209 408 5.0E-57 T 29-03-2018 SMALA_RS33280 30249904e858b5799e1774ca096b38d4 408 Pfam PF00480 ROK family 93 357 5.3E-31 T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 SMALA_RS33280 30249904e858b5799e1774ca096b38d4 408 Gene3D G3DSA:3.30.420.40 83 208 6.3E-24 T 29-03-2018 SMALA_RS33280 30249904e858b5799e1774ca096b38d4 408 SUPERFAMILY SSF53067 92 402 3.84E-36 T 29-03-2018 SMALA_RS33280 30249904e858b5799e1774ca096b38d4 408 SUPERFAMILY SSF46785 20 84 2.96E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS25240 f6b5442e8687b22007e2c4978dc1e474 358 Gene3D G3DSA:1.20.910.10 124 357 3.8E-28 T 29-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 SMALA_RS25240 f6b5442e8687b22007e2c4978dc1e474 358 SMART SM01236 198 301 8.8E-24 T 29-03-2018 SMALA_RS25240 f6b5442e8687b22007e2c4978dc1e474 358 Pfam PF14518 Iron-containing redox enzyme 168 338 5.4E-30 T 29-03-2018 IPR028201 PqqC-like protein SMALA_RS25240 f6b5442e8687b22007e2c4978dc1e474 358 SUPERFAMILY SSF48613 132 330 7.23E-14 T 29-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 SMALA_RS13915 868cb3f46ef9f042728c68d4b72da0c5 788 Pfam PF03176 MMPL family 55 379 1.0E-42 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 SMALA_RS13915 868cb3f46ef9f042728c68d4b72da0c5 788 Pfam PF03176 MMPL family 411 720 1.8E-35 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 SMALA_RS13915 868cb3f46ef9f042728c68d4b72da0c5 788 Gene3D G3DSA:1.20.1640.10 120 345 1.0E-29 T 29-03-2018 SMALA_RS13915 868cb3f46ef9f042728c68d4b72da0c5 788 Gene3D G3DSA:1.20.1640.10 494 717 3.4E-27 T 29-03-2018 SMALA_RS13915 868cb3f46ef9f042728c68d4b72da0c5 788 SUPERFAMILY SSF82866 513 719 8.76E-23 T 29-03-2018 SMALA_RS13915 868cb3f46ef9f042728c68d4b72da0c5 788 SUPERFAMILY SSF82866 157 345 1.09E-28 T 29-03-2018 SMALA_RS10325 b8a341e1c81bb99bbc4c3f9b09c719ac 217 Pfam PF02581 Thiamine monophosphate synthase 16 197 1.8E-51 T 29-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 SMALA_RS10325 b8a341e1c81bb99bbc4c3f9b09c719ac 217 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 15 209 1.2E-58 T 29-03-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 SMALA_RS10325 b8a341e1c81bb99bbc4c3f9b09c719ac 217 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 14 215 24.108 T 29-03-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 SMALA_RS10325 b8a341e1c81bb99bbc4c3f9b09c719ac 217 SUPERFAMILY SSF51391 9 212 4.05E-60 T 29-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 SMALA_RS10325 b8a341e1c81bb99bbc4c3f9b09c719ac 217 Gene3D G3DSA:3.20.20.70 5 215 3.4E-46 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS05040 6e0ec2f20a0d518ced2e7f6c7342ba58 353 SUPERFAMILY SSF53850 50 274 1.13E-28 T 29-03-2018 SMALA_RS05040 6e0ec2f20a0d518ced2e7f6c7342ba58 353 Gene3D G3DSA:3.40.190.10 45 142 9.4E-5 T 29-03-2018 SMALA_RS05040 6e0ec2f20a0d518ced2e7f6c7342ba58 353 Gene3D G3DSA:3.40.190.10 143 277 2.9E-17 T 29-03-2018 SMALA_RS05040 6e0ec2f20a0d518ced2e7f6c7342ba58 353 Pfam PF09084 NMT1/THI5 like 89 215 3.6E-10 T 29-03-2018 IPR015168 SsuA/THI5-like SMALA_RS11735 53474b612af163c41482d438f9992586 217 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 12 203 37.65 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMALA_RS11735 53474b612af163c41482d438f9992586 217 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 122 135 - T 29-03-2018 IPR033135 ClpP, histidine active site SMALA_RS11735 53474b612af163c41482d438f9992586 217 Pfam PF00574 Clp protease 30 201 7.3E-72 T 29-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA SMALA_RS11735 53474b612af163c41482d438f9992586 217 PRINTS PR00127 Clp protease catalytic subunit P signature 29 44 1.0E-41 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMALA_RS11735 53474b612af163c41482d438f9992586 217 PRINTS PR00127 Clp protease catalytic subunit P signature 178 197 1.0E-41 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMALA_RS11735 53474b612af163c41482d438f9992586 217 PRINTS PR00127 Clp protease catalytic subunit P signature 121 140 1.0E-41 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMALA_RS11735 53474b612af163c41482d438f9992586 217 PRINTS PR00127 Clp protease catalytic subunit P signature 69 89 1.0E-41 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMALA_RS11735 53474b612af163c41482d438f9992586 217 PRINTS PR00127 Clp protease catalytic subunit P signature 100 117 1.0E-41 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMALA_RS11735 53474b612af163c41482d438f9992586 217 SUPERFAMILY SSF52096 31 202 1.24E-61 T 29-03-2018 IPR029045 ClpP/crotonase-like domain SMALA_RS11735 53474b612af163c41482d438f9992586 217 Gene3D G3DSA:3.90.226.10 31 203 1.4E-39 T 29-03-2018 SMALA_RS39410 85b03450b372597a46902c8ea311fa4e 370 Gene3D G3DSA:3.40.190.10 62 197 5.7E-14 T 29-03-2018 SMALA_RS39410 85b03450b372597a46902c8ea311fa4e 370 SUPERFAMILY SSF53850 61 325 4.73E-41 T 29-03-2018 SMALA_RS39410 85b03450b372597a46902c8ea311fa4e 370 Gene3D G3DSA:3.40.190.10 198 334 1.3E-10 T 29-03-2018 SMALA_RS39410 85b03450b372597a46902c8ea311fa4e 370 Pfam PF13343 Bacterial extracellular solute-binding protein 131 329 9.6E-14 T 29-03-2018 SMALA_RS41895 d609a817cdc214ffc7408eb0cbc8858f 379 SUPERFAMILY SSF56645 7 228 6.81E-64 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMALA_RS41895 d609a817cdc214ffc7408eb0cbc8858f 379 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 125 213 5.4E-22 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 SMALA_RS41895 d609a817cdc214ffc7408eb0cbc8858f 379 SUPERFAMILY SSF47203 227 378 3.38E-54 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMALA_RS41895 d609a817cdc214ffc7408eb0cbc8858f 379 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 229 377 1.9E-47 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMALA_RS41895 d609a817cdc214ffc7408eb0cbc8858f 379 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 120 3.2E-24 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS41895 d609a817cdc214ffc7408eb0cbc8858f 379 Gene3D G3DSA:1.10.540.10 5 124 4.8E-28 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS41895 d609a817cdc214ffc7408eb0cbc8858f 379 Gene3D G3DSA:1.20.140.10 227 379 2.9E-51 T 29-03-2018 SMALA_RS41895 d609a817cdc214ffc7408eb0cbc8858f 379 PIRSF PIRSF016578 2 192 1.0E-10 T 29-03-2018 SMALA_RS41895 d609a817cdc214ffc7408eb0cbc8858f 379 PIRSF PIRSF016578 235 376 9.5E-9 T 29-03-2018 SMALA_RS41895 d609a817cdc214ffc7408eb0cbc8858f 379 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 336 355 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 SMALA_RS41895 d609a817cdc214ffc7408eb0cbc8858f 379 Gene3D G3DSA:2.40.110.10 125 226 2.6E-30 T 29-03-2018 SMALA_RS35050 50b661c2117322c79473cbdbcc9e805e 310 Gene3D G3DSA:3.10.129.10 209 300 3.6E-4 T 29-03-2018 SMALA_RS35050 50b661c2117322c79473cbdbcc9e805e 310 Pfam PF03756 A-factor biosynthesis hotdog domain 30 167 4.1E-20 T 29-03-2018 IPR005509 A-factor biosynthesis hotdog domain SMALA_RS35050 50b661c2117322c79473cbdbcc9e805e 310 Pfam PF03756 A-factor biosynthesis hotdog domain 216 255 5.7E-9 T 29-03-2018 IPR005509 A-factor biosynthesis hotdog domain SMALA_RS40590 efaa9750704f72a777403fd68348e6b2 500 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 79 408 1.1E-74 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain SMALA_RS40590 efaa9750704f72a777403fd68348e6b2 500 Gene3D G3DSA:3.40.190.10 159 286 1.3E-35 T 29-03-2018 SMALA_RS40590 efaa9750704f72a777403fd68348e6b2 500 Gene3D G3DSA:3.10.105.10 287 469 2.9E-34 T 29-03-2018 SMALA_RS40590 efaa9750704f72a777403fd68348e6b2 500 PIRSF PIRSF002741 4 494 4.4E-82 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 SMALA_RS40590 efaa9750704f72a777403fd68348e6b2 500 SUPERFAMILY SSF53850 33 488 1.53E-106 T 29-03-2018 SMALA_RS40590 efaa9750704f72a777403fd68348e6b2 500 Gene3D G3DSA:3.90.76.10 60 158 2.2E-30 T 29-03-2018 SMALA_RS19155 22fbfde5bf0927c839831aee8645d8ea 370 Gene3D G3DSA:3.50.50.60 1 354 2.8E-35 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS19155 22fbfde5bf0927c839831aee8645d8ea 370 SUPERFAMILY SSF51905 3 168 5.11E-45 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS19155 22fbfde5bf0927c839831aee8645d8ea 370 SUPERFAMILY SSF51905 273 349 5.11E-45 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS19155 22fbfde5bf0927c839831aee8645d8ea 370 Pfam PF01494 FAD binding domain 3 188 6.6E-9 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 SMALA_RS19155 22fbfde5bf0927c839831aee8645d8ea 370 Pfam PF01494 FAD binding domain 290 325 3.9E-5 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 SMALA_RS19155 22fbfde5bf0927c839831aee8645d8ea 370 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 1.9E-14 T 29-03-2018 SMALA_RS19155 22fbfde5bf0927c839831aee8645d8ea 370 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 147 162 1.9E-14 T 29-03-2018 SMALA_RS19155 22fbfde5bf0927c839831aee8645d8ea 370 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 288 303 1.9E-14 T 29-03-2018 SMALA_RS30195 378b5c38a9ecde0be01ae1a119f14ab2 759 Gene3D G3DSA:1.20.1640.10 141 354 1.7E-32 T 29-03-2018 SMALA_RS30195 378b5c38a9ecde0be01ae1a119f14ab2 759 SUPERFAMILY SSF82866 125 350 1.05E-30 T 29-03-2018 SMALA_RS30195 378b5c38a9ecde0be01ae1a119f14ab2 759 Gene3D G3DSA:1.20.1640.10 495 714 3.4E-31 T 29-03-2018 SMALA_RS30195 378b5c38a9ecde0be01ae1a119f14ab2 759 SUPERFAMILY SSF82866 470 715 3.66E-29 T 29-03-2018 SMALA_RS30195 378b5c38a9ecde0be01ae1a119f14ab2 759 Pfam PF03176 MMPL family 418 719 5.6E-36 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 SMALA_RS30195 378b5c38a9ecde0be01ae1a119f14ab2 759 Pfam PF03176 MMPL family 81 383 2.5E-53 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 SMALA_RS41560 7f584ae3c3a5539e856082ba0a46bc7d 312 SUPERFAMILY SSF54593 7 286 1.54E-35 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS41560 7f584ae3c3a5539e856082ba0a46bc7d 312 Gene3D G3DSA:3.10.180.10 135 287 2.0E-27 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS41560 7f584ae3c3a5539e856082ba0a46bc7d 312 Gene3D G3DSA:3.10.180.10 1 134 1.6E-19 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS41560 7f584ae3c3a5539e856082ba0a46bc7d 312 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 120 2.1E-5 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMALA_RS41560 7f584ae3c3a5539e856082ba0a46bc7d 312 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 142 256 2.5E-15 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMALA_RS09540 e11997531953058cce11499829ec1258 377 Pfam PF10128 Glucose-6-phosphate dehydrogenase subunit 51 298 6.3E-84 T 29-03-2018 IPR004555 Glucose-6-phosphate dehydrogenase assembly protein OpcA SMALA_RS09540 e11997531953058cce11499829ec1258 377 TIGRFAM TIGR00534 OpcA: glucose-6-phosphate dehydrogenase assembly protein OpcA 1 296 3.5E-92 T 29-03-2018 IPR004555 Glucose-6-phosphate dehydrogenase assembly protein OpcA SMALA_RS08005 39214692f4b3d97438c4444476a10814 218 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 19 208 9.6E-67 T 29-03-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 SMALA_RS08005 39214692f4b3d97438c4444476a10814 218 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 15 210 39.381 T 29-03-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 SMALA_RS08005 39214692f4b3d97438c4444476a10814 218 Pfam PF00925 GTP cyclohydrolase II 19 184 1.4E-64 T 29-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 SMALA_RS08005 39214692f4b3d97438c4444476a10814 218 SUPERFAMILY SSF142695 17 186 3.4E-59 T 29-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 SMALA_RS02545 f903c31bd1833b8f81c260fc204635ac 418 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 357 366 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMALA_RS02545 f903c31bd1833b8f81c260fc204635ac 418 PRINTS PR00385 P450 superfamily signature 364 375 5.8E-6 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS02545 f903c31bd1833b8f81c260fc204635ac 418 PRINTS PR00385 P450 superfamily signature 253 270 5.8E-6 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS02545 f903c31bd1833b8f81c260fc204635ac 418 PRINTS PR00385 P450 superfamily signature 355 364 5.8E-6 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS02545 f903c31bd1833b8f81c260fc204635ac 418 PRINTS PR00385 P450 superfamily signature 288 299 5.8E-6 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS02545 f903c31bd1833b8f81c260fc204635ac 418 PRINTS PR00359 B-class P450 signature 288 299 7.2E-48 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS02545 f903c31bd1833b8f81c260fc204635ac 418 PRINTS PR00359 B-class P450 signature 355 364 7.2E-48 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS02545 f903c31bd1833b8f81c260fc204635ac 418 PRINTS PR00359 B-class P450 signature 334 349 7.2E-48 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS02545 f903c31bd1833b8f81c260fc204635ac 418 PRINTS PR00359 B-class P450 signature 170 185 7.2E-48 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS02545 f903c31bd1833b8f81c260fc204635ac 418 PRINTS PR00359 B-class P450 signature 306 333 7.2E-48 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS02545 f903c31bd1833b8f81c260fc204635ac 418 PRINTS PR00359 B-class P450 signature 364 375 7.2E-48 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS02545 f903c31bd1833b8f81c260fc204635ac 418 PRINTS PR00359 B-class P450 signature 207 229 7.2E-48 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS02545 f903c31bd1833b8f81c260fc204635ac 418 PRINTS PR00359 B-class P450 signature 106 117 7.2E-48 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS02545 f903c31bd1833b8f81c260fc204635ac 418 PRINTS PR00359 B-class P450 signature 153 169 7.2E-48 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS02545 f903c31bd1833b8f81c260fc204635ac 418 Gene3D G3DSA:1.10.630.10 18 417 3.0E-75 T 29-03-2018 SMALA_RS02545 f903c31bd1833b8f81c260fc204635ac 418 Pfam PF00067 Cytochrome P450 221 385 4.1E-24 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS02545 f903c31bd1833b8f81c260fc204635ac 418 SUPERFAMILY SSF48264 36 415 1.7E-90 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS15985 5a6f6526f52bf2587e333aaf1a2b015d 226 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 223 3.9E-28 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS15985 5a6f6526f52bf2587e333aaf1a2b015d 226 SMART SM00448 2 113 3.0E-41 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS15985 5a6f6526f52bf2587e333aaf1a2b015d 226 SMART SM00862 147 223 4.4E-29 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS15985 5a6f6526f52bf2587e333aaf1a2b015d 226 Gene3D G3DSA:3.40.50.2300 1 123 8.2E-38 T 29-03-2018 SMALA_RS15985 5a6f6526f52bf2587e333aaf1a2b015d 226 Gene3D G3DSA:1.10.10.10 124 226 1.5E-33 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS15985 5a6f6526f52bf2587e333aaf1a2b015d 226 SUPERFAMILY SSF52172 1 128 2.42E-40 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS15985 5a6f6526f52bf2587e333aaf1a2b015d 226 SUPERFAMILY SSF46894 125 224 3.97E-30 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS15985 5a6f6526f52bf2587e333aaf1a2b015d 226 Pfam PF00072 Response regulator receiver domain 4 114 6.1E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS27570 06966470fc56601ad2ed4fa6c58bdfb5 219 Pfam PF03458 UPF0126 domain 13 87 1.2E-18 T 29-03-2018 IPR005115 Uncharacterised domain UPF0126 SMALA_RS27570 06966470fc56601ad2ed4fa6c58bdfb5 219 Pfam PF03458 UPF0126 domain 99 173 2.2E-20 T 29-03-2018 IPR005115 Uncharacterised domain UPF0126 SMALA_RS31075 e47da20bf7c1c53134271ea80e3bf97c 109 Pfam PF04673 Polyketide synthesis cyclase 3 105 2.5E-44 T 29-03-2018 IPR006765 Polyketide synthesis cyclase GO:0030639 SMALA_RS31075 e47da20bf7c1c53134271ea80e3bf97c 109 Gene3D G3DSA:3.30.70.1090 3 105 4.3E-37 T 29-03-2018 SMALA_RS31075 e47da20bf7c1c53134271ea80e3bf97c 109 SUPERFAMILY SSF54909 1 106 1.39E-38 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel SMALA_RS31075 e47da20bf7c1c53134271ea80e3bf97c 109 ProDom PD012644 CYCLASE POLYKETIDE II SYNTHESIS ORF SYNTHASE JADI BIOSYNTHESIS ANTIBIOTIC CYCLASE-LIKE 2 105 7.0E-36 T 29-03-2018 IPR006765 Polyketide synthesis cyclase GO:0030639 SMALA_RS22390 6a932585d2f3507803031f400657d5bc 156 Hamap MF_00799 UPF0336 protein . 1 149 35.182 T 29-03-2018 IPR016709 Uncharacterised protein family UPF0336 SMALA_RS22390 6a932585d2f3507803031f400657d5bc 156 PIRSF PIRSF018072 1 151 4.2E-58 T 29-03-2018 IPR016709 Uncharacterised protein family UPF0336 SMALA_RS22390 6a932585d2f3507803031f400657d5bc 156 Pfam PF13452 N-terminal half of MaoC dehydratase 7 138 2.3E-35 T 29-03-2018 SMALA_RS22390 6a932585d2f3507803031f400657d5bc 156 SUPERFAMILY SSF54637 7 148 6.33E-39 T 29-03-2018 IPR029069 HotDog domain SMALA_RS22390 6a932585d2f3507803031f400657d5bc 156 Gene3D G3DSA:3.10.129.10 3 156 2.7E-42 T 29-03-2018 SMALA_RS13320 b6835704dc8fbdef4ea9d0d931828497 213 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 165 172 - T 29-03-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 SMALA_RS13320 b6835704dc8fbdef4ea9d0d931828497 213 Gene3D G3DSA:1.10.287.990 21 84 3.2E-17 T 29-03-2018 SMALA_RS13320 b6835704dc8fbdef4ea9d0d931828497 213 SUPERFAMILY SSF46609 3 89 6.42E-30 T 29-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 SMALA_RS13320 b6835704dc8fbdef4ea9d0d931828497 213 PIRSF PIRSF000349 1 208 1.9E-69 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 SMALA_RS13320 b6835704dc8fbdef4ea9d0d931828497 213 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 98 198 1.9E-31 T 29-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 SMALA_RS13320 b6835704dc8fbdef4ea9d0d931828497 213 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 4 83 1.6E-29 T 29-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 SMALA_RS13320 b6835704dc8fbdef4ea9d0d931828497 213 PRINTS PR01703 Manganese superoxide dismutase signature 125 133 4.5E-19 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 SMALA_RS13320 b6835704dc8fbdef4ea9d0d931828497 213 PRINTS PR01703 Manganese superoxide dismutase signature 163 175 4.5E-19 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 SMALA_RS13320 b6835704dc8fbdef4ea9d0d931828497 213 PRINTS PR01703 Manganese superoxide dismutase signature 28 41 4.5E-19 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 SMALA_RS13320 b6835704dc8fbdef4ea9d0d931828497 213 PRINTS PR01703 Manganese superoxide dismutase signature 7 18 4.5E-19 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 SMALA_RS13320 b6835704dc8fbdef4ea9d0d931828497 213 PRINTS PR01703 Manganese superoxide dismutase signature 67 80 4.5E-19 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 SMALA_RS13320 b6835704dc8fbdef4ea9d0d931828497 213 SUPERFAMILY SSF54719 98 206 1.96E-36 T 29-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 SMALA_RS27555 f313d3539971db99f5415447f19c650e 324 Gene3D G3DSA:1.10.3720.10 94 320 3.7E-37 T 29-03-2018 SMALA_RS27555 f313d3539971db99f5415447f19c650e 324 SUPERFAMILY SSF161098 99 310 4.3E-16 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS27555 f313d3539971db99f5415447f19c650e 324 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 124 322 9.9E-40 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS06030 df1843d06e6b1f7eb7ded50f306dcd05 404 Gene3D G3DSA:3.30.390.10 1 112 1.8E-35 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMALA_RS06030 df1843d06e6b1f7eb7ded50f306dcd05 404 SUPERFAMILY SSF54826 1 112 1.34E-32 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMALA_RS06030 df1843d06e6b1f7eb7ded50f306dcd05 404 Gene3D G3DSA:3.20.20.120 113 377 1.3E-60 T 29-03-2018 IPR029065 Enolase C-terminal domain-like SMALA_RS06030 df1843d06e6b1f7eb7ded50f306dcd05 404 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 14 110 6.0E-32 T 29-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain SMALA_RS06030 df1843d06e6b1f7eb7ded50f306dcd05 404 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 85 110 - T 29-03-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 SMALA_RS06030 df1843d06e6b1f7eb7ded50f306dcd05 404 SMART SM00922 128 259 6.6E-22 T 29-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal SMALA_RS06030 df1843d06e6b1f7eb7ded50f306dcd05 404 Pfam PF13378 Enolase C-terminal domain-like 134 379 1.0E-42 T 29-03-2018 IPR029065 Enolase C-terminal domain-like SMALA_RS06030 df1843d06e6b1f7eb7ded50f306dcd05 404 SUPERFAMILY SSF51604 98 387 4.08E-74 T 29-03-2018 IPR029065 Enolase C-terminal domain-like SMALA_RS26330 aa52a9d19b36f608c2b1a4de0b9bbc78 85 Pfam PF02467 Transcription factor WhiB 3 71 1.2E-27 T 29-03-2018 IPR034768 WhiB-like iron-sulfur binding domain SMALA_RS26330 aa52a9d19b36f608c2b1a4de0b9bbc78 85 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 76 19.172 T 29-03-2018 IPR003482 Transcription factor WhiB SMALA_RS09840 86407fcbc2b54f924a697b59ebea07cf 252 Gene3D G3DSA:1.10.10.10 1 43 6.9E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS09840 86407fcbc2b54f924a697b59ebea07cf 252 Gene3D G3DSA:3.10.28.10 172 249 5.2E-6 T 29-03-2018 IPR027434 Homing endonuclease GO:0004519 SMALA_RS09840 86407fcbc2b54f924a697b59ebea07cf 252 Gene3D G3DSA:3.10.28.10 60 171 1.1E-23 T 29-03-2018 IPR027434 Homing endonuclease GO:0004519 SMALA_RS30645 67b7fc66bc29603fa5345e38952eeb11 384 Gene3D G3DSA:3.30.420.40 152 357 2.9E-62 T 29-03-2018 SMALA_RS30645 67b7fc66bc29603fa5345e38952eeb11 384 SUPERFAMILY SSF53067 37 348 1.19E-70 T 29-03-2018 SMALA_RS30645 67b7fc66bc29603fa5345e38952eeb11 384 Pfam PF00480 ROK family 37 347 2.5E-81 T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 SMALA_RS30645 67b7fc66bc29603fa5345e38952eeb11 384 ProSitePatterns PS01125 ROK family signature. 166 193 - T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 SMALA_RS30645 67b7fc66bc29603fa5345e38952eeb11 384 Gene3D G3DSA:3.30.420.40 22 151 9.9E-35 T 29-03-2018 SMALA_RS30645 67b7fc66bc29603fa5345e38952eeb11 384 TIGRFAM TIGR00744 ROK_glcA_fam: ROK family protein (putative glucokinase) 38 347 6.1E-93 T 29-03-2018 IPR004654 Glucokinase ROK GO:0004340|GO:0005737|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 SMALA_RS22095 e8bb57b943565591533b117fc20ae5bd 139 Pfam PF00571 CBS domain 81 125 1.5E-11 T 29-03-2018 IPR000644 CBS domain SMALA_RS22095 e8bb57b943565591533b117fc20ae5bd 139 Pfam PF00571 CBS domain 5 55 4.0E-9 T 29-03-2018 IPR000644 CBS domain SMALA_RS22095 e8bb57b943565591533b117fc20ae5bd 139 SMART SM00116 11 59 2.8E-5 T 29-03-2018 IPR000644 CBS domain SMALA_RS22095 e8bb57b943565591533b117fc20ae5bd 139 SMART SM00116 77 125 6.5E-10 T 29-03-2018 IPR000644 CBS domain SMALA_RS22095 e8bb57b943565591533b117fc20ae5bd 139 Gene3D G3DSA:3.10.580.10 1 136 8.6E-30 T 29-03-2018 SMALA_RS22095 e8bb57b943565591533b117fc20ae5bd 139 SUPERFAMILY SSF54631 2 132 1.39E-33 T 29-03-2018 SMALA_RS42960 1e83357c607f00cd7b5a2b6817a9f17c 193 SUPERFAMILY SSF88946 27 87 6.28E-6 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS42960 1e83357c607f00cd7b5a2b6817a9f17c 193 Pfam PF08281 Sigma-70, region 4 124 174 4.5E-10 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS42960 1e83357c607f00cd7b5a2b6817a9f17c 193 SUPERFAMILY SSF88659 108 177 4.11E-10 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS42960 1e83357c607f00cd7b5a2b6817a9f17c 193 Gene3D G3DSA:1.10.10.10 107 185 6.7E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS42960 1e83357c607f00cd7b5a2b6817a9f17c 193 Gene3D G3DSA:1.10.1740.10 19 90 4.1E-5 T 29-03-2018 SMALA_RS34240 0cff4e366f681410f255585465392544 318 Pfam PF00294 pfkB family carbohydrate kinase 7 302 3.7E-47 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB SMALA_RS34240 0cff4e366f681410f255585465392544 318 Gene3D G3DSA:3.40.1190.20 3 317 3.0E-56 T 29-03-2018 IPR029056 Ribokinase-like SMALA_RS34240 0cff4e366f681410f255585465392544 318 SUPERFAMILY SSF53613 5 305 4.21E-63 T 29-03-2018 IPR029056 Ribokinase-like SMALA_RS14625 cf5bb032dac43613da45933b6f58f7d6 253 Pfam PF09339 IclR helix-turn-helix domain 13 62 7.6E-7 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMALA_RS14625 cf5bb032dac43613da45933b6f58f7d6 253 Gene3D G3DSA:3.30.450.40 84 251 1.7E-23 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS14625 cf5bb032dac43613da45933b6f58f7d6 253 Pfam PF01614 Bacterial transcriptional regulator 134 230 2.2E-13 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal SMALA_RS14625 cf5bb032dac43613da45933b6f58f7d6 253 SUPERFAMILY SSF55781 92 242 7.19E-22 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS14625 cf5bb032dac43613da45933b6f58f7d6 253 SUPERFAMILY SSF46785 12 79 2.33E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS14625 cf5bb032dac43613da45933b6f58f7d6 253 Gene3D G3DSA:1.10.10.10 2 69 6.3E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS22585 3f50ccf8806a6bca0e8002ce123e4350 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 29-03-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMALA_RS22585 3f50ccf8806a6bca0e8002ce123e4350 122 SMART SM01374 1 122 1.9E-87 T 29-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 SMALA_RS22585 3f50ccf8806a6bca0e8002ce123e4350 122 SUPERFAMILY SSF50193 2 122 3.01E-50 T 29-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 SMALA_RS22585 3f50ccf8806a6bca0e8002ce123e4350 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 5.1E-57 T 29-03-2018 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 SMALA_RS22585 3f50ccf8806a6bca0e8002ce123e4350 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 27.009 T 29-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 SMALA_RS22585 3f50ccf8806a6bca0e8002ce123e4350 122 Pfam PF00238 Ribosomal protein L14p/L23e 2 122 3.3E-54 T 29-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 SMALA_RS22585 3f50ccf8806a6bca0e8002ce123e4350 122 Gene3D G3DSA:2.40.150.20 1 122 5.2E-53 T 29-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 SMALA_RS24745 912d0b3ff2db8c5e6083ea651c4b31ae 184 Gene3D G3DSA:3.30.1020.10 153 183 5.9E-6 T 29-03-2018 SMALA_RS24745 912d0b3ff2db8c5e6083ea651c4b31ae 184 SUPERFAMILY SSF52833 2 177 7.97E-53 T 29-03-2018 IPR012336 Thioredoxin-like fold SMALA_RS24745 912d0b3ff2db8c5e6083ea651c4b31ae 184 PIRSF PIRSF000239 1 184 8.8E-49 T 29-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 SMALA_RS24745 912d0b3ff2db8c5e6083ea651c4b31ae 184 Pfam PF00578 AhpC/TSA family 4 136 1.3E-32 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 SMALA_RS24745 912d0b3ff2db8c5e6083ea651c4b31ae 184 Gene3D G3DSA:3.40.30.10 1 152 1.4E-36 T 29-03-2018 SMALA_RS30975 54a1dadda2c87200ea507991839e0a01 117 SUPERFAMILY SSF54593 9 112 7.29E-13 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS30975 54a1dadda2c87200ea507991839e0a01 117 Gene3D G3DSA:3.10.180.10 6 117 1.8E-11 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS33325 ae6df27bfeb3f19b5c1cc40ba09ae6b5 455 Gene3D G3DSA:3.10.580.10 199 346 1.9E-29 T 29-03-2018 SMALA_RS33325 ae6df27bfeb3f19b5c1cc40ba09ae6b5 455 SMART SM01091 359 437 6.5E-18 T 29-03-2018 IPR005170 Transporter-associated domain SMALA_RS33325 ae6df27bfeb3f19b5c1cc40ba09ae6b5 455 Pfam PF00571 CBS domain 220 272 3.4E-4 T 29-03-2018 IPR000644 CBS domain SMALA_RS33325 ae6df27bfeb3f19b5c1cc40ba09ae6b5 455 Pfam PF00571 CBS domain 288 337 3.3E-5 T 29-03-2018 IPR000644 CBS domain SMALA_RS33325 ae6df27bfeb3f19b5c1cc40ba09ae6b5 455 Pfam PF03471 Transporter associated domain 362 435 1.3E-15 T 29-03-2018 IPR005170 Transporter-associated domain SMALA_RS33325 ae6df27bfeb3f19b5c1cc40ba09ae6b5 455 Gene3D G3DSA:3.30.465.10 347 437 3.9E-22 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SMALA_RS33325 ae6df27bfeb3f19b5c1cc40ba09ae6b5 455 Pfam PF01595 Domain of unknown function DUF21 11 202 8.6E-37 T 29-03-2018 IPR002550 Domain of unknown function DUF21 SMALA_RS33325 ae6df27bfeb3f19b5c1cc40ba09ae6b5 455 SUPERFAMILY SSF56176 362 439 9.27E-17 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SMALA_RS33325 ae6df27bfeb3f19b5c1cc40ba09ae6b5 455 SUPERFAMILY SSF54631 213 349 2.02E-26 T 29-03-2018 SMALA_RS09340 aadc23ca6f5afd8dadbbfc90ec320e9f 300 SUPERFAMILY SSF51569 13 298 1.78E-65 T 29-03-2018 SMALA_RS09340 aadc23ca6f5afd8dadbbfc90ec320e9f 300 Gene3D G3DSA:3.20.20.70 5 299 4.0E-67 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS09340 aadc23ca6f5afd8dadbbfc90ec320e9f 300 Pfam PF00701 Dihydrodipicolinate synthetase family 11 296 6.0E-48 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SMALA_RS09340 aadc23ca6f5afd8dadbbfc90ec320e9f 300 PIRSF PIRSF001365 7 299 8.0E-65 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SMALA_RS09340 aadc23ca6f5afd8dadbbfc90ec320e9f 300 SMART SM01130 9 299 9.8E-63 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SMALA_RS20110 463def4eabf1a25f1f365fd61d031808 608 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 162 271 3.7E-18 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 SMALA_RS20110 463def4eabf1a25f1f365fd61d031808 608 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 473 604 7.3E-30 T 29-03-2018 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain SMALA_RS20110 463def4eabf1a25f1f365fd61d031808 608 Gene3D G3DSA:1.20.140.10 279 469 2.2E-32 T 29-03-2018 SMALA_RS20110 463def4eabf1a25f1f365fd61d031808 608 Gene3D G3DSA:1.20.120.470 470 603 1.8E-4 T 29-03-2018 SMALA_RS20110 463def4eabf1a25f1f365fd61d031808 608 SUPERFAMILY SSF56645 43 272 2.49E-41 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMALA_RS20110 463def4eabf1a25f1f365fd61d031808 608 SUPERFAMILY SSF47203 290 469 2.42E-32 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMALA_RS20110 463def4eabf1a25f1f365fd61d031808 608 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 286 452 1.4E-15 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMALA_RS20110 463def4eabf1a25f1f365fd61d031808 608 Gene3D G3DSA:2.40.110.10 156 272 1.1E-24 T 29-03-2018 SMALA_RS20110 463def4eabf1a25f1f365fd61d031808 608 Pfam PF12418 Acyl-CoA dehydrogenase N terminal 3 34 3.6E-10 T 29-03-2018 IPR020953 Acyl-CoA dehydrogenase, N-terminal, bacteria SMALA_RS20110 463def4eabf1a25f1f365fd61d031808 608 Gene3D G3DSA:1.10.540.10 34 155 6.3E-6 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS17050 a75289384a6b54ac70a857d4a07bb477 536 Pfam PF00171 Aldehyde dehydrogenase family 45 500 4.7E-142 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS17050 a75289384a6b54ac70a857d4a07bb477 536 SUPERFAMILY SSF53720 38 503 2.49E-140 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMALA_RS17050 a75289384a6b54ac70a857d4a07bb477 536 Gene3D G3DSA:3.40.309.10 291 485 1.4E-63 T 29-03-2018 SMALA_RS17050 a75289384a6b54ac70a857d4a07bb477 536 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 272 279 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 SMALA_RS17050 a75289384a6b54ac70a857d4a07bb477 536 Gene3D G3DSA:3.40.605.10 34 290 1.1E-74 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS37625 a99b41cd2691f849008301d631e5d87b 397 Gene3D G3DSA:3.40.50.720 175 351 6.3E-29 T 29-03-2018 SMALA_RS37625 a99b41cd2691f849008301d631e5d87b 397 SUPERFAMILY SSF51735 156 356 2.8E-43 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS37625 a99b41cd2691f849008301d631e5d87b 397 SUPERFAMILY SSF50129 1 177 1.89E-57 T 29-03-2018 IPR011032 GroES-like SMALA_RS37625 a99b41cd2691f849008301d631e5d87b 397 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 142 3.7E-28 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS37625 a99b41cd2691f849008301d631e5d87b 397 Pfam PF13823 Alcohol dehydrogenase GroES-associated 1 22 4.6E-13 T 29-03-2018 IPR027399 Alcohol dehydrogenase GroES-associated SMALA_RS37625 a99b41cd2691f849008301d631e5d87b 397 Pfam PF00107 Zinc-binding dehydrogenase 189 262 1.4E-9 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMALA_RS37625 a99b41cd2691f849008301d631e5d87b 397 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 SMALA_RS37625 a99b41cd2691f849008301d631e5d87b 397 Gene3D G3DSA:3.90.180.10 1 174 1.6E-45 T 29-03-2018 SMALA_RS04660 351a8451b8e22ff77c93744862c3049c 251 SMART SM00345 29 85 1.0E-8 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS04660 351a8451b8e22ff77c93744862c3049c 251 SUPERFAMILY SSF46785 20 94 2.5E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS04660 351a8451b8e22ff77c93744862c3049c 251 Gene3D G3DSA:1.10.10.10 28 88 3.4E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS04660 351a8451b8e22ff77c93744862c3049c 251 SMART SM00866 105 244 1.3E-32 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMALA_RS04660 351a8451b8e22ff77c93744862c3049c 251 Gene3D G3DSA:3.40.1410.10 89 251 5.6E-41 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMALA_RS04660 351a8451b8e22ff77c93744862c3049c 251 Pfam PF00392 Bacterial regulatory proteins, gntR family 29 85 5.2E-12 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS04660 351a8451b8e22ff77c93744862c3049c 251 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 60 76 1.3E-8 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS04660 351a8451b8e22ff77c93744862c3049c 251 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 46 60 1.3E-8 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS04660 351a8451b8e22ff77c93744862c3049c 251 Pfam PF07702 UTRA domain 106 243 1.5E-32 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMALA_RS04660 351a8451b8e22ff77c93744862c3049c 251 SUPERFAMILY SSF64288 77 250 2.83E-45 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMALA_RS31235 a66ac54bb8c0f7c30cbd40a3de4dd10c 276 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 230 245 - T 29-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 SMALA_RS31235 a66ac54bb8c0f7c30cbd40a3de4dd10c 276 SUPERFAMILY SSF51430 6 268 1.13E-94 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS31235 a66ac54bb8c0f7c30cbd40a3de4dd10c 276 PIRSF PIRSF000097 2 272 9.3E-86 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMALA_RS31235 a66ac54bb8c0f7c30cbd40a3de4dd10c 276 Pfam PF00248 Aldo/keto reductase family 18 261 2.0E-51 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS31235 a66ac54bb8c0f7c30cbd40a3de4dd10c 276 Gene3D G3DSA:3.20.20.100 1 275 1.1E-97 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS31235 a66ac54bb8c0f7c30cbd40a3de4dd10c 276 PRINTS PR00069 Aldo-keto reductase signature 159 188 2.7E-47 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMALA_RS31235 a66ac54bb8c0f7c30cbd40a3de4dd10c 276 PRINTS PR00069 Aldo-keto reductase signature 37 61 2.7E-47 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMALA_RS31235 a66ac54bb8c0f7c30cbd40a3de4dd10c 276 PRINTS PR00069 Aldo-keto reductase signature 197 221 2.7E-47 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMALA_RS31235 a66ac54bb8c0f7c30cbd40a3de4dd10c 276 PRINTS PR00069 Aldo-keto reductase signature 93 111 2.7E-47 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMALA_RS31235 a66ac54bb8c0f7c30cbd40a3de4dd10c 276 PRINTS PR00069 Aldo-keto reductase signature 125 142 2.7E-47 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMALA_RS31235 a66ac54bb8c0f7c30cbd40a3de4dd10c 276 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 125 142 - T 29-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 SMALA_RS06470 8224980643defc8eb81008e31b2d216a 526 SUPERFAMILY SSF51905 263 366 4.06E-64 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS06470 8224980643defc8eb81008e31b2d216a 526 SUPERFAMILY SSF51905 4 174 4.06E-64 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS06470 8224980643defc8eb81008e31b2d216a 526 Pfam PF01494 FAD binding domain 4 334 6.1E-63 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 SMALA_RS06470 8224980643defc8eb81008e31b2d216a 526 Gene3D G3DSA:3.50.50.60 1 379 8.5E-56 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS06470 8224980643defc8eb81008e31b2d216a 526 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 276 291 2.9E-34 T 29-03-2018 SMALA_RS06470 8224980643defc8eb81008e31b2d216a 526 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 291 307 2.9E-34 T 29-03-2018 SMALA_RS06470 8224980643defc8eb81008e31b2d216a 526 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 2.9E-34 T 29-03-2018 SMALA_RS06470 8224980643defc8eb81008e31b2d216a 526 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 153 168 2.9E-34 T 29-03-2018 SMALA_RS06470 8224980643defc8eb81008e31b2d216a 526 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 309 327 2.9E-34 T 29-03-2018 SMALA_RS13190 76bc8729585937e302611313cef54ae2 504 Pfam PF02875 Mur ligase family, glutamate ligase domain 363 442 1.9E-12 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 SMALA_RS13190 76bc8729585937e302611313cef54ae2 504 Gene3D G3DSA:3.40.1190.10 65 363 2.4E-82 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMALA_RS13190 76bc8729585937e302611313cef54ae2 504 Pfam PF08245 Mur ligase middle domain 107 334 1.6E-13 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMALA_RS13190 76bc8729585937e302611313cef54ae2 504 SUPERFAMILY SSF53623 65 359 2.44E-87 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMALA_RS13190 76bc8729585937e302611313cef54ae2 504 Gene3D G3DSA:3.90.190.20 364 504 1.5E-32 T 29-03-2018 SMALA_RS13190 76bc8729585937e302611313cef54ae2 504 TIGRFAM TIGR01499 folC: bifunctional protein FolC 86 498 1.7E-99 T 29-03-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 SMALA_RS13190 76bc8729585937e302611313cef54ae2 504 ProSitePatterns PS01012 Folylpolyglutamate synthase signature 2. 203 218 - T 29-03-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 SMALA_RS13190 76bc8729585937e302611313cef54ae2 504 SUPERFAMILY SSF53244 364 502 1.52E-27 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 SMALA_RS39595 d473267da100cc0e96dc91c2ff087b8b 1231 TIGRFAM TIGR01580 narG: nitrate reductase, alpha subunit 32 1225 0.0 T 29-03-2018 IPR006468 Nitrate reductase, alpha subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.99.4 SMALA_RS39595 d473267da100cc0e96dc91c2ff087b8b 1231 Pfam PF01568 Molydopterin dinucleotide binding domain 1085 1195 2.6E-22 T 29-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 SMALA_RS39595 d473267da100cc0e96dc91c2ff087b8b 1231 SUPERFAMILY SSF53706 24 1066 0.0 T 29-03-2018 SMALA_RS39595 d473267da100cc0e96dc91c2ff087b8b 1231 SUPERFAMILY SSF50692 1079 1224 5.65E-43 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain SMALA_RS39595 d473267da100cc0e96dc91c2ff087b8b 1231 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 62 80 - T 29-03-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 KEGG: 00910+1.7.99.4 SMALA_RS39595 d473267da100cc0e96dc91c2ff087b8b 1231 Gene3D G3DSA:3.40.50.740 122 231 4.9E-5 T 29-03-2018 SMALA_RS39595 d473267da100cc0e96dc91c2ff087b8b 1231 Gene3D G3DSA:2.20.25.90 69 112 6.7E-26 T 29-03-2018 SMALA_RS39595 d473267da100cc0e96dc91c2ff087b8b 1231 Gene3D G3DSA:3.40.228.10 236 658 2.9E-96 T 29-03-2018 SMALA_RS39595 d473267da100cc0e96dc91c2ff087b8b 1231 Gene3D G3DSA:3.40.228.10 721 974 0.0084 T 29-03-2018 SMALA_RS39595 d473267da100cc0e96dc91c2ff087b8b 1231 SMART SM00926 57 119 6.9E-5 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS39595 d473267da100cc0e96dc91c2ff087b8b 1231 Gene3D G3DSA:2.40.40.20 1046 1231 1.0E-43 T 29-03-2018 SMALA_RS39595 d473267da100cc0e96dc91c2ff087b8b 1231 Pfam PF00384 Molybdopterin oxidoreductase 122 827 4.1E-144 T 29-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS42200 6a8e7a5a0f2867476cfdb6d7e7c91c01 678 Gene3D G3DSA:1.10.260.40 19 123 1.9E-4 T 29-03-2018 SMALA_RS42200 6a8e7a5a0f2867476cfdb6d7e7c91c01 678 Gene3D G3DSA:3.40.190.10 529 671 1.1E-6 T 29-03-2018 SMALA_RS42200 6a8e7a5a0f2867476cfdb6d7e7c91c01 678 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 442 455 - T 29-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 SMALA_RS42200 6a8e7a5a0f2867476cfdb6d7e7c91c01 678 SMART SM00062 420 665 3.9E-41 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SMALA_RS42200 6a8e7a5a0f2867476cfdb6d7e7c91c01 678 Gene3D G3DSA:1.20.5.170 124 198 0.026 T 29-03-2018 SMALA_RS42200 6a8e7a5a0f2867476cfdb6d7e7c91c01 678 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 421 660 1.8E-38 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SMALA_RS42200 6a8e7a5a0f2867476cfdb6d7e7c91c01 678 Gene3D G3DSA:3.40.190.10 411 528 3.0E-27 T 29-03-2018 SMALA_RS42200 6a8e7a5a0f2867476cfdb6d7e7c91c01 678 SUPERFAMILY SSF53850 390 660 3.75E-40 T 29-03-2018 SMALA_RS42200 6a8e7a5a0f2867476cfdb6d7e7c91c01 678 Gene3D G3DSA:1.20.5.1070 199 296 0.0046 T 29-03-2018 SMALA_RS08665 81615163a148552aa6df89f5698190d8 238 Gene3D G3DSA:3.40.50.300 14 235 1.6E-43 T 29-03-2018 SMALA_RS08665 81615163a148552aa6df89f5698190d8 238 SUPERFAMILY SSF52540 16 234 9.93E-36 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS08665 81615163a148552aa6df89f5698190d8 238 Pfam PF02224 Cytidylate kinase 18 232 2.4E-67 T 29-03-2018 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 SMALA_RS08665 81615163a148552aa6df89f5698190d8 238 Hamap MF_00238 Cytidylate kinase [cmk]. 16 235 31.393 T 29-03-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 SMALA_RS08665 81615163a148552aa6df89f5698190d8 238 TIGRFAM TIGR00017 cmk: cytidylate kinase 16 229 5.0E-66 T 29-03-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 SMALA_RS22980 3f7fdbfe9d63ef81c86677b86d456cf4 811 Gene3D G3DSA:2.60.40.10 142 259 1.0E-7 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS22980 3f7fdbfe9d63ef81c86677b86d456cf4 811 Gene3D G3DSA:2.60.40.10 681 779 0.0053 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS31155 715b235efe78702d06cc8f4a2e3f2993 819 SUPERFAMILY SSF55781 291 441 1.66E-12 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS31155 715b235efe78702d06cc8f4a2e3f2993 819 SUPERFAMILY SSF55781 3 136 1.92E-9 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS31155 715b235efe78702d06cc8f4a2e3f2993 819 Gene3D G3DSA:3.30.450.20 133 259 4.9E-14 T 29-03-2018 SMALA_RS31155 715b235efe78702d06cc8f4a2e3f2993 819 Gene3D G3DSA:3.30.565.10 673 811 2.8E-9 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS31155 715b235efe78702d06cc8f4a2e3f2993 819 Gene3D G3DSA:3.60.40.10 439 670 4.4E-35 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS31155 715b235efe78702d06cc8f4a2e3f2993 819 SUPERFAMILY SSF81606 473 667 1.36E-5 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS31155 715b235efe78702d06cc8f4a2e3f2993 819 SUPERFAMILY SSF55874 704 780 5.01E-5 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS31155 715b235efe78702d06cc8f4a2e3f2993 819 SMART SM00086 223 265 0.0011 T 29-03-2018 IPR001610 PAC motif SMALA_RS31155 715b235efe78702d06cc8f4a2e3f2993 819 SMART SM00331 455 668 2.2E-23 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS31155 715b235efe78702d06cc8f4a2e3f2993 819 Gene3D G3DSA:3.30.450.40 260 438 4.7E-19 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS31155 715b235efe78702d06cc8f4a2e3f2993 819 Pfam PF13581 Histidine kinase-like ATPase domain 683 779 6.3E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS31155 715b235efe78702d06cc8f4a2e3f2993 819 Pfam PF08447 PAS fold 172 259 1.6E-15 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 SMALA_RS31155 715b235efe78702d06cc8f4a2e3f2993 819 SUPERFAMILY SSF55785 157 259 1.92E-11 T 29-03-2018 IPR000014 PAS domain SMALA_RS31155 715b235efe78702d06cc8f4a2e3f2993 819 Gene3D G3DSA:3.30.450.40 1 132 2.1E-13 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS31155 715b235efe78702d06cc8f4a2e3f2993 819 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 485 668 5.6E-43 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS31155 715b235efe78702d06cc8f4a2e3f2993 819 Pfam PF13185 GAF domain 286 428 3.5E-7 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS03505 15a1cb01bf7d7219af3c575b1b84fec2 265 Pfam PF09339 IclR helix-turn-helix domain 21 70 4.0E-15 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMALA_RS03505 15a1cb01bf7d7219af3c575b1b84fec2 265 SUPERFAMILY SSF46785 19 88 1.61E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS03505 15a1cb01bf7d7219af3c575b1b84fec2 265 SUPERFAMILY SSF55781 76 263 1.83E-47 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS03505 15a1cb01bf7d7219af3c575b1b84fec2 265 Gene3D G3DSA:1.10.10.10 1 79 4.1E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS03505 15a1cb01bf7d7219af3c575b1b84fec2 265 Pfam PF01614 Bacterial transcriptional regulator 137 259 3.0E-31 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal SMALA_RS03505 15a1cb01bf7d7219af3c575b1b84fec2 265 SMART SM00346 19 108 7.4E-24 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMALA_RS03505 15a1cb01bf7d7219af3c575b1b84fec2 265 Gene3D G3DSA:3.30.450.40 90 264 3.7E-47 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS28470 e7daab63a92b5846a957b77427764f93 95 Gene3D G3DSA:3.30.1230.10 2 94 1.6E-24 T 29-03-2018 IPR007393 Domain of unknown function DUF448 SMALA_RS28470 e7daab63a92b5846a957b77427764f93 95 SUPERFAMILY SSF64376 10 89 9.29E-22 T 29-03-2018 IPR007393 Domain of unknown function DUF448 SMALA_RS28470 e7daab63a92b5846a957b77427764f93 95 Pfam PF04296 Protein of unknown function (DUF448) 13 73 5.2E-21 T 29-03-2018 IPR007393 Domain of unknown function DUF448 SMALA_RS25645 be4cb3ca5ca6b24d5f2952397c75ed2d 374 PRINTS PR00412 Epoxide hydrolase signature 173 186 1.8E-12 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS25645 be4cb3ca5ca6b24d5f2952397c75ed2d 374 PRINTS PR00412 Epoxide hydrolase signature 128 143 1.8E-12 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS25645 be4cb3ca5ca6b24d5f2952397c75ed2d 374 PRINTS PR00412 Epoxide hydrolase signature 347 369 1.8E-12 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS25645 be4cb3ca5ca6b24d5f2952397c75ed2d 374 PRINTS PR00412 Epoxide hydrolase signature 187 200 1.8E-12 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS25645 be4cb3ca5ca6b24d5f2952397c75ed2d 374 PRINTS PR00412 Epoxide hydrolase signature 99 117 1.8E-12 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS25645 be4cb3ca5ca6b24d5f2952397c75ed2d 374 Pfam PF06441 Epoxide hydrolase N terminus 3 108 1.1E-36 T 29-03-2018 IPR010497 Epoxide hydrolase, N-terminal KEGG: 00980+3.3.2.9|Reactome: R-HSA-211945 SMALA_RS25645 be4cb3ca5ca6b24d5f2952397c75ed2d 374 Gene3D G3DSA:3.40.50.1820 1 374 4.8E-79 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS25645 be4cb3ca5ca6b24d5f2952397c75ed2d 374 PIRSF PIRSF001112 1 374 2.1E-119 T 29-03-2018 IPR016292 Epoxide hydrolase GO:0033961 KEGG: 00980+3.3.2.9|Reactome: R-HSA-211945 SMALA_RS25645 be4cb3ca5ca6b24d5f2952397c75ed2d 374 SUPERFAMILY SSF53474 2 372 4.39E-95 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS24800 4a623b9a9519b896d64034c5eb0ae843 747 Gene3D G3DSA:1.10.101.10 81 131 5.0E-4 T 29-03-2018 IPR002477 Peptidoglycan binding-like SMALA_RS24800 4a623b9a9519b896d64034c5eb0ae843 747 Pfam PF01471 Putative peptidoglycan binding domain 248 282 1.9E-4 T 29-03-2018 IPR002477 Peptidoglycan binding-like SMALA_RS24800 4a623b9a9519b896d64034c5eb0ae843 747 SUPERFAMILY SSF47090 222 288 6.12E-6 T 29-03-2018 IPR002477 Peptidoglycan binding-like SMALA_RS24800 4a623b9a9519b896d64034c5eb0ae843 747 Pfam PF08924 Domain of unknown function (DUF1906) 305 432 1.5E-36 T 29-03-2018 IPR015020 Protein of unknown function DUF1906 SMALA_RS24800 4a623b9a9519b896d64034c5eb0ae843 747 Gene3D G3DSA:1.10.101.10 138 293 5.9E-12 T 29-03-2018 IPR002477 Peptidoglycan binding-like SMALA_RS24800 4a623b9a9519b896d64034c5eb0ae843 747 Gene3D G3DSA:1.10.101.10 1 75 0.31 T 29-03-2018 IPR002477 Peptidoglycan binding-like SMALA_RS24800 4a623b9a9519b896d64034c5eb0ae843 747 Gene3D G3DSA:3.20.20.80 294 498 2.5E-26 T 29-03-2018 SMALA_RS24800 4a623b9a9519b896d64034c5eb0ae843 747 SUPERFAMILY SSF51445 294 477 4.63E-37 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS23805 182652e0132e5e8236b328fe62ed477a 267 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 4 262 6.5E-68 T 29-03-2018 SMALA_RS23805 182652e0132e5e8236b328fe62ed477a 267 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 4 262 6.5E-71 T 29-03-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 SMALA_RS23805 182652e0132e5e8236b328fe62ed477a 267 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 6 256 3.1E-19 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMALA_RS23805 182652e0132e5e8236b328fe62ed477a 267 Gene3D G3DSA:3.60.10.10 1 264 8.9E-52 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMALA_RS23805 182652e0132e5e8236b328fe62ed477a 267 SUPERFAMILY SSF56219 2 263 4.71E-70 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMALA_RS15445 209d09a19c1256938f6360f1b85a6b99 254 SUPERFAMILY SSF161098 1 254 1.44E-60 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS15445 209d09a19c1256938f6360f1b85a6b99 254 Gene3D G3DSA:1.10.3720.10 1 246 2.2E-35 T 29-03-2018 SMALA_RS15445 209d09a19c1256938f6360f1b85a6b99 254 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 79 246 5.1E-15 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS01315 230bc71555fe1eb026f856e14cb0f79f 381 SUPERFAMILY SSF48264 5 380 5.37E-48 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS01315 230bc71555fe1eb026f856e14cb0f79f 381 PRINTS PR00359 B-class P450 signature 328 339 1.3E-9 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS01315 230bc71555fe1eb026f856e14cb0f79f 381 PRINTS PR00359 B-class P450 signature 162 184 1.3E-9 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS01315 230bc71555fe1eb026f856e14cb0f79f 381 PRINTS PR00359 B-class P450 signature 239 250 1.3E-9 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS01315 230bc71555fe1eb026f856e14cb0f79f 381 PRINTS PR00359 B-class P450 signature 319 328 1.3E-9 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS01315 230bc71555fe1eb026f856e14cb0f79f 381 PRINTS PR00359 B-class P450 signature 50 61 1.3E-9 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS01315 230bc71555fe1eb026f856e14cb0f79f 381 PRINTS PR00385 P450 superfamily signature 319 328 5.8E-5 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS01315 230bc71555fe1eb026f856e14cb0f79f 381 PRINTS PR00385 P450 superfamily signature 328 339 5.8E-5 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS01315 230bc71555fe1eb026f856e14cb0f79f 381 PRINTS PR00385 P450 superfamily signature 239 250 5.8E-5 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS01315 230bc71555fe1eb026f856e14cb0f79f 381 PRINTS PR00385 P450 superfamily signature 203 220 5.8E-5 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS01315 230bc71555fe1eb026f856e14cb0f79f 381 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 321 330 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMALA_RS01315 230bc71555fe1eb026f856e14cb0f79f 381 Pfam PF00067 Cytochrome P450 239 346 1.3E-9 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS01315 230bc71555fe1eb026f856e14cb0f79f 381 Gene3D G3DSA:1.10.630.10 1 381 1.9E-43 T 29-03-2018 SMALA_RS33590 ad920abfd99cd3a35f25096a6c9aac57 315 Pfam PF13649 Methyltransferase domain 99 193 1.6E-13 T 29-03-2018 SMALA_RS33590 ad920abfd99cd3a35f25096a6c9aac57 315 SUPERFAMILY SSF53335 73 305 1.79E-32 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS33590 ad920abfd99cd3a35f25096a6c9aac57 315 Gene3D G3DSA:3.40.50.150 34 304 2.6E-28 T 29-03-2018 SMALA_RS29540 94f109302e1b96ca238517b80480b2e7 576 Gene3D G3DSA:3.40.50.980 9 178 4.2E-34 T 29-03-2018 SMALA_RS29540 94f109302e1b96ca238517b80480b2e7 576 SUPERFAMILY SSF56801 7 566 4.58E-104 T 29-03-2018 SMALA_RS29540 94f109302e1b96ca238517b80480b2e7 576 Pfam PF00501 AMP-binding enzyme 19 461 6.1E-76 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS29540 94f109302e1b96ca238517b80480b2e7 576 Gene3D G3DSA:3.30.300.30 454 564 3.3E-14 T 29-03-2018 SMALA_RS29540 94f109302e1b96ca238517b80480b2e7 576 Gene3D G3DSA:3.40.50.980 179 344 6.2E-36 T 29-03-2018 SMALA_RS29540 94f109302e1b96ca238517b80480b2e7 576 ProSitePatterns PS00455 Putative AMP-binding domain signature. 173 184 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS29540 94f109302e1b96ca238517b80480b2e7 576 Gene3D G3DSA:2.30.38.10 355 453 8.2E-19 T 29-03-2018 SMALA_RS17720 02534cf24715ab8ea76d56af98c0d8b7 307 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 90 230 1.1E-29 T 29-03-2018 IPR006342 Methyltransferase FkbM SMALA_RS17720 02534cf24715ab8ea76d56af98c0d8b7 307 Gene3D G3DSA:3.40.50.150 74 275 3.2E-37 T 29-03-2018 SMALA_RS17720 02534cf24715ab8ea76d56af98c0d8b7 307 Pfam PF05050 Methyltransferase FkbM domain 93 259 6.4E-15 T 29-03-2018 IPR006342 Methyltransferase FkbM SMALA_RS17720 02534cf24715ab8ea76d56af98c0d8b7 307 SUPERFAMILY SSF53335 41 267 2.89E-52 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS38790 718f473f379b48a17c7d1595a0483fdb 126 SUPERFAMILY SSF54637 2 115 3.6E-28 T 29-03-2018 IPR029069 HotDog domain SMALA_RS38790 718f473f379b48a17c7d1595a0483fdb 126 Gene3D G3DSA:3.10.129.10 1 123 4.0E-28 T 29-03-2018 SMALA_RS38790 718f473f379b48a17c7d1595a0483fdb 126 TIGRFAM TIGR02286 PaaD: phenylacetic acid degradation protein PaaD 9 119 1.4E-44 T 29-03-2018 IPR011973 Phenylacetic acid degradation protein PaaD GO:0016790 SMALA_RS38790 718f473f379b48a17c7d1595a0483fdb 126 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 9 115 3.1E-19 T 29-03-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 SMALA_RS38790 718f473f379b48a17c7d1595a0483fdb 126 Pfam PF03061 Thioesterase superfamily 37 109 3.3E-12 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 SMALA_RS01905 7c786c34444f1e1517edd5e45f8aff16 178 Pfam PF07681 DoxX 8 91 2.5E-15 T 29-03-2018 IPR032808 DoxX family SMALA_RS35430 ed41924109a0d63051b8c0e872fd395a 208 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 129 153 4.3E-22 T 29-03-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 SMALA_RS35430 ed41924109a0d63051b8c0e872fd395a 208 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 70 96 4.3E-22 T 29-03-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 SMALA_RS35430 ed41924109a0d63051b8c0e872fd395a 208 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 154 178 4.3E-22 T 29-03-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 SMALA_RS35430 ed41924109a0d63051b8c0e872fd395a 208 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 181 195 4.3E-22 T 29-03-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 SMALA_RS35430 ed41924109a0d63051b8c0e872fd395a 208 Pfam PF02031 Streptomyces extracellular neutral proteinase (M7) family 65 190 8.9E-30 T 29-03-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 SMALA_RS35430 ed41924109a0d63051b8c0e872fd395a 208 ProDom PD016028 PROTEASE METALLOPROTEASE EXTRACELLULAR NEUTRAL SMALL METAL-BINDING ZINC HYDROLASE SNAPALYSIN ZYMOGEN 71 189 1.0E-50 T 29-03-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 SMALA_RS35430 ed41924109a0d63051b8c0e872fd395a 208 Gene3D G3DSA:3.40.390.10 65 194 4.3E-15 T 29-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 SMALA_RS35430 ed41924109a0d63051b8c0e872fd395a 208 SUPERFAMILY SSF55486 64 189 1.7E-20 T 29-03-2018 SMALA_RS35430 ed41924109a0d63051b8c0e872fd395a 208 PIRSF PIRSF016573 23 206 8.2E-35 T 29-03-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 SMALA_RS41640 845d8ff3413c515d42dd2b3199e30a8c 108 Gene3D G3DSA:3.30.70.100 1 106 3.0E-15 T 29-03-2018 SMALA_RS41640 845d8ff3413c515d42dd2b3199e30a8c 108 Pfam PF07978 NIPSNAP 4 94 1.3E-8 T 29-03-2018 IPR012577 NIPSNAP SMALA_RS41640 845d8ff3413c515d42dd2b3199e30a8c 108 SUPERFAMILY SSF54909 2 98 3.75E-13 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel SMALA_RS19260 48e5d4f36511da3f9ec4992340cfa90b 559 Gene3D G3DSA:3.30.450.40 45 309 3.4E-36 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS19260 48e5d4f36511da3f9ec4992340cfa90b 559 SMART SM00331 335 558 7.5E-15 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS19260 48e5d4f36511da3f9ec4992340cfa90b 559 Gene3D G3DSA:3.60.40.10 310 559 6.6E-28 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS19260 48e5d4f36511da3f9ec4992340cfa90b 559 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 359 558 1.2E-33 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS38580 424f3d9a7329e9362ce020c14bf7ad7b 173 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 10 132 8.9E-15 T 29-03-2018 IPR005031 Coenzyme Q-binding protein COQ10, START domain Reactome: R-HSA-611105 SMALA_RS38580 424f3d9a7329e9362ce020c14bf7ad7b 173 SUPERFAMILY SSF55961 1 145 2.04E-21 T 29-03-2018 SMALA_RS38580 424f3d9a7329e9362ce020c14bf7ad7b 173 Gene3D G3DSA:3.30.530.20 2 151 6.8E-18 T 29-03-2018 IPR023393 START-like domain SMALA_RS26085 0b2270284e57659fc139296415d5e3f8 369 Gene3D G3DSA:3.40.50.720 19 326 5.0E-30 T 29-03-2018 SMALA_RS26085 0b2270284e57659fc139296415d5e3f8 369 SUPERFAMILY SSF51735 21 324 2.79E-30 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS26085 0b2270284e57659fc139296415d5e3f8 369 Pfam PF01370 NAD dependent epimerase/dehydratase family 25 233 1.5E-15 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 SMALA_RS23675 aeb175eb3b93bc1582a852e560bcda4b 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 7.3E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS23675 aeb175eb3b93bc1582a852e560bcda4b 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 7.3E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS23675 aeb175eb3b93bc1582a852e560bcda4b 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 7.3E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS23675 aeb175eb3b93bc1582a852e560bcda4b 245 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 243 3.5E-61 T 29-03-2018 SMALA_RS23675 aeb175eb3b93bc1582a852e560bcda4b 245 Gene3D G3DSA:3.40.50.720 1 40 2.7E-9 T 29-03-2018 SMALA_RS23675 aeb175eb3b93bc1582a852e560bcda4b 245 Gene3D G3DSA:3.40.50.720 41 245 1.7E-65 T 29-03-2018 SMALA_RS23675 aeb175eb3b93bc1582a852e560bcda4b 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 1.0E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS23675 aeb175eb3b93bc1582a852e560bcda4b 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.0E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS23675 aeb175eb3b93bc1582a852e560bcda4b 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.0E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS23675 aeb175eb3b93bc1582a852e560bcda4b 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 1.0E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS23675 aeb175eb3b93bc1582a852e560bcda4b 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 227 1.0E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS23675 aeb175eb3b93bc1582a852e560bcda4b 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 1.0E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS23675 aeb175eb3b93bc1582a852e560bcda4b 245 SUPERFAMILY SSF51735 4 243 1.42E-79 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS23675 aeb175eb3b93bc1582a852e560bcda4b 245 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 185 0.0031 T 29-03-2018 SMALA_RS19395 3476fee565c06f79af2eb03d1ce96f07 266 SUPERFAMILY SSF56784 1 264 1.24E-53 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS19395 3476fee565c06f79af2eb03d1ce96f07 266 Gene3D G3DSA:3.40.50.1000 1 266 2.1E-32 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS19395 3476fee565c06f79af2eb03d1ce96f07 266 Pfam PF08282 haloacid dehalogenase-like hydrolase 2 260 1.0E-45 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS19395 3476fee565c06f79af2eb03d1ce96f07 266 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 1 260 2.4E-41 T 29-03-2018 IPR000150 Cof family GO:0016787 SMALA_RS10595 73bf789eb8a521b6b1d9d62233a0005f 392 Gene3D G3DSA:3.40.50.10800 260 368 1.9E-23 T 29-03-2018 SMALA_RS10595 73bf789eb8a521b6b1d9d62233a0005f 392 Gene3D G3DSA:3.40.50.10800 45 144 5.0E-17 T 29-03-2018 SMALA_RS10595 73bf789eb8a521b6b1d9d62233a0005f 392 Pfam PF02445 Quinolinate synthetase A protein 51 389 4.4E-106 T 29-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 SMALA_RS10595 73bf789eb8a521b6b1d9d62233a0005f 392 Gene3D G3DSA:3.40.50.10800 145 259 8.1E-25 T 29-03-2018 SMALA_RS10595 73bf789eb8a521b6b1d9d62233a0005f 392 SUPERFAMILY SSF142754 50 389 1.44E-92 T 29-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 SMALA_RS10595 73bf789eb8a521b6b1d9d62233a0005f 392 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 45 391 1.6E-99 T 29-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 SMALA_RS10595 73bf789eb8a521b6b1d9d62233a0005f 392 Hamap MF_00569 Quinolinate synthase A [nadA]. 41 391 56.564 T 29-03-2018 IPR023515 Quinolinate synthase A, type 3 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342 SMALA_RS31610 bdd5b12d2db0434ba3e973ba4c1bf2b8 712 Gene3D G3DSA:3.30.450.40 293 476 7.8E-21 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS31610 bdd5b12d2db0434ba3e973ba4c1bf2b8 712 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 527 708 1.4E-46 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS31610 bdd5b12d2db0434ba3e973ba4c1bf2b8 712 SMART SM00331 496 707 5.1E-42 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS31610 bdd5b12d2db0434ba3e973ba4c1bf2b8 712 Gene3D G3DSA:3.60.40.10 477 709 9.1E-39 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS31610 bdd5b12d2db0434ba3e973ba4c1bf2b8 712 SUPERFAMILY SSF81606 513 707 2.75E-10 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS31610 bdd5b12d2db0434ba3e973ba4c1bf2b8 712 SUPERFAMILY SSF55785 183 267 1.08E-6 T 29-03-2018 IPR000014 PAS domain SMALA_RS31610 bdd5b12d2db0434ba3e973ba4c1bf2b8 712 Gene3D G3DSA:3.30.450.40 13 150 8.2E-6 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS31610 bdd5b12d2db0434ba3e973ba4c1bf2b8 712 Gene3D G3DSA:3.30.450.20 163 290 1.4E-6 T 29-03-2018 SMALA_RS31610 bdd5b12d2db0434ba3e973ba4c1bf2b8 712 SUPERFAMILY SSF55781 335 481 6.98E-16 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS31610 bdd5b12d2db0434ba3e973ba4c1bf2b8 712 SMART SM00065 328 478 0.0073 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS31610 bdd5b12d2db0434ba3e973ba4c1bf2b8 712 Pfam PF13185 GAF domain 333 469 3.9E-13 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS07430 955a06aaf3938d61474f1f35d7fc9782 330 Gene3D G3DSA:1.20.58.340 263 330 2.6E-20 T 29-03-2018 SMALA_RS07430 955a06aaf3938d61474f1f35d7fc9782 330 SUPERFAMILY SSF144083 265 327 1.14E-19 T 29-03-2018 SMALA_RS07430 955a06aaf3938d61474f1f35d7fc9782 330 Gene3D G3DSA:1.20.58.340 143 262 1.3E-30 T 29-03-2018 SMALA_RS07430 955a06aaf3938d61474f1f35d7fc9782 330 Pfam PF01544 CorA-like Mg2+ transporter protein 36 326 3.2E-65 T 29-03-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 SMALA_RS07430 955a06aaf3938d61474f1f35d7fc9782 330 Gene3D G3DSA:3.30.460.20 1 135 5.7E-37 T 29-03-2018 SMALA_RS07430 955a06aaf3938d61474f1f35d7fc9782 330 SUPERFAMILY SSF143865 4 262 4.58E-66 T 29-03-2018 SMALA_RS07430 955a06aaf3938d61474f1f35d7fc9782 330 TIGRFAM TIGR00383 corA: magnesium and cobalt transport protein CorA 29 330 1.5E-61 T 29-03-2018 IPR004488 Magnesium/cobalt transport protein CorA GO:0006824|GO:0015087|GO:0015095|GO:0015693|GO:0016020 SMALA_RS14865 e400d1d8a2bfa6e20f0554c65ddb323f 222 Gene3D G3DSA:3.40.50.2300 5 137 1.9E-37 T 29-03-2018 SMALA_RS14865 e400d1d8a2bfa6e20f0554c65ddb323f 222 Pfam PF00196 Bacterial regulatory proteins, luxR family 157 212 7.8E-17 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS14865 e400d1d8a2bfa6e20f0554c65ddb323f 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 172 1.5E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS14865 e400d1d8a2bfa6e20f0554c65ddb323f 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 188 200 1.5E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS14865 e400d1d8a2bfa6e20f0554c65ddb323f 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 188 1.5E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS14865 e400d1d8a2bfa6e20f0554c65ddb323f 222 SMART SM00421 155 212 3.2E-25 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS14865 e400d1d8a2bfa6e20f0554c65ddb323f 222 Gene3D G3DSA:1.10.10.10 138 217 1.8E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS14865 e400d1d8a2bfa6e20f0554c65ddb323f 222 SUPERFAMILY SSF52172 5 186 3.08E-33 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS14865 e400d1d8a2bfa6e20f0554c65ddb323f 222 SMART SM00448 6 119 9.5E-29 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS14865 e400d1d8a2bfa6e20f0554c65ddb323f 222 Pfam PF00072 Response regulator receiver domain 8 117 2.2E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS23175 409abce42400011438b3bc130d00271b 819 PRINTS PR00364 Disease resistance protein signature 290 304 4.7E-8 T 29-03-2018 SMALA_RS23175 409abce42400011438b3bc130d00271b 819 PRINTS PR00364 Disease resistance protein signature 203 217 4.7E-8 T 29-03-2018 SMALA_RS23175 409abce42400011438b3bc130d00271b 819 PRINTS PR00364 Disease resistance protein signature 126 141 4.7E-8 T 29-03-2018 SMALA_RS23175 409abce42400011438b3bc130d00271b 819 SMART SM00028 543 576 0.079 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS23175 409abce42400011438b3bc130d00271b 819 SMART SM00028 701 734 50.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS23175 409abce42400011438b3bc130d00271b 819 SMART SM00028 661 694 31.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS23175 409abce42400011438b3bc130d00271b 819 SMART SM00028 581 614 11.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS23175 409abce42400011438b3bc130d00271b 819 SMART SM00028 621 654 330.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS23175 409abce42400011438b3bc130d00271b 819 SMART SM00028 740 773 15.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS23175 409abce42400011438b3bc130d00271b 819 Gene3D G3DSA:1.10.150.200 633 669 3.2E-4 T 29-03-2018 SMALA_RS23175 409abce42400011438b3bc130d00271b 819 Gene3D G3DSA:1.10.150.200 587 632 3.4E-6 T 29-03-2018 SMALA_RS23175 409abce42400011438b3bc130d00271b 819 Gene3D G3DSA:1.10.150.200 520 586 7.5E-6 T 29-03-2018 SMALA_RS23175 409abce42400011438b3bc130d00271b 819 SUPERFAMILY SSF48452 583 693 3.24E-13 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS23175 409abce42400011438b3bc130d00271b 819 Gene3D G3DSA:3.40.50.300 85 245 1.3E-17 T 29-03-2018 SMALA_RS23175 409abce42400011438b3bc130d00271b 819 Pfam PF00931 NB-ARC domain 106 310 1.1E-11 T 29-03-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207 SMALA_RS23175 409abce42400011438b3bc130d00271b 819 Pfam PF13424 Tetratricopeptide repeat 582 652 1.8E-7 T 29-03-2018 SMALA_RS23175 409abce42400011438b3bc130d00271b 819 Gene3D G3DSA:1.25.40.10 670 793 2.3E-14 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS23175 409abce42400011438b3bc130d00271b 819 SUPERFAMILY SSF48452 701 769 3.41E-14 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS23175 409abce42400011438b3bc130d00271b 819 SUPERFAMILY SSF48452 543 614 3.41E-14 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS23175 409abce42400011438b3bc130d00271b 819 Pfam PF13181 Tetratricopeptide repeat 543 575 0.0032 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS23175 409abce42400011438b3bc130d00271b 819 SUPERFAMILY SSF52540 95 357 1.24E-26 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS31905 c12271341a3d3905f658f4a99e318932 66 Pfam PF04149 Domain of unknown function (DUF397) 10 64 1.6E-24 T 29-03-2018 IPR007278 Domain of unknown function DUF397 SMALA_RS04580 493ff643b32d5c73b2a115da447077c9 507 Gene3D G3DSA:3.40.720.10 46 416 2.4E-87 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 SMALA_RS04580 493ff643b32d5c73b2a115da447077c9 507 PIRSF PIRSF036666 6 505 3.4E-93 T 29-03-2018 IPR012251 N-acetylglucosamine-6-sulfatase GO:0008449|GO:0030203 KEGG: 00531+3.1.6.14|Reactome: R-HSA-2022857|Reactome: R-HSA-432720|Reactome: R-HSA-6798695 SMALA_RS04580 493ff643b32d5c73b2a115da447077c9 507 ProSitePatterns PS00523 Sulfatases signature 1. 88 100 - T 29-03-2018 IPR024607 Sulfatase, conserved site SMALA_RS04580 493ff643b32d5c73b2a115da447077c9 507 Gene3D G3DSA:3.30.1120.10 427 507 1.6E-6 T 29-03-2018 SMALA_RS04580 493ff643b32d5c73b2a115da447077c9 507 Pfam PF00884 Sulfatase 49 383 2.1E-62 T 29-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 SMALA_RS04580 493ff643b32d5c73b2a115da447077c9 507 SUPERFAMILY SSF53649 47 493 1.29E-109 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 SMALA_RS22180 3ab4b370ef5217d4b1d2bc32fa16cae7 416 Gene3D G3DSA:3.90.850.10 111 398 2.4E-80 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 SMALA_RS22180 3ab4b370ef5217d4b1d2bc32fa16cae7 416 Pfam PF09298 Fumarylacetoacetase N-terminal 18 113 1.9E-15 T 29-03-2018 IPR015377 Fumarylacetoacetase, N-terminal GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 SMALA_RS22180 3ab4b370ef5217d4b1d2bc32fa16cae7 416 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 119 412 1.5E-52 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 SMALA_RS22180 3ab4b370ef5217d4b1d2bc32fa16cae7 416 TIGRFAM TIGR01266 fum_ac_acetase: fumarylacetoacetase 9 414 6.7E-123 T 29-03-2018 IPR005959 Fumarylacetoacetase GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 SMALA_RS22180 3ab4b370ef5217d4b1d2bc32fa16cae7 416 SUPERFAMILY SSF63433 4 113 1.31E-20 T 29-03-2018 IPR015377 Fumarylacetoacetase, N-terminal GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 SMALA_RS22180 3ab4b370ef5217d4b1d2bc32fa16cae7 416 Gene3D G3DSA:2.30.30.230 5 103 3.5E-23 T 29-03-2018 IPR015377 Fumarylacetoacetase, N-terminal GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 SMALA_RS22180 3ab4b370ef5217d4b1d2bc32fa16cae7 416 SUPERFAMILY SSF56529 115 414 1.06E-85 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 SMALA_RS24600 0b46727cc7e8a3187fe5b582bf722431 301 Gene3D G3DSA:3.40.50.150 3 81 6.2E-4 T 29-03-2018 SMALA_RS31600 1f413c178516acc5d35426f09cfdb466 460 SUPERFAMILY SSF103473 14 456 4.45E-70 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS31600 1f413c178516acc5d35426f09cfdb466 460 Gene3D G3DSA:1.20.1250.20 31 228 3.8E-31 T 29-03-2018 SMALA_RS31600 1f413c178516acc5d35426f09cfdb466 460 Pfam PF00083 Sugar (and other) transporter 60 457 1.3E-55 T 29-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 SMALA_RS31600 1f413c178516acc5d35426f09cfdb466 460 Gene3D G3DSA:1.20.1250.20 263 460 3.1E-25 T 29-03-2018 SMALA_RS34580 a220aabb35832e7c7833b653f6ef011a 208 ProSitePatterns PS00910 Uncharacterized protein family UPF0029 signature. 79 108 - T 29-03-2018 IPR020569 Uncharacterised protein family UPF0029, Impact, conserved site SMALA_RS34580 a220aabb35832e7c7833b653f6ef011a 208 SUPERFAMILY SSF54980 137 199 1.04E-15 T 29-03-2018 IPR035647 EF-G domain III/V-like SMALA_RS34580 a220aabb35832e7c7833b653f6ef011a 208 Gene3D G3DSA:3.30.230.30 4 133 5.1E-43 T 29-03-2018 IPR001498 Impact, N-terminal SMALA_RS34580 a220aabb35832e7c7833b653f6ef011a 208 Pfam PF01205 Uncharacterized protein family UPF0029 20 124 2.9E-29 T 29-03-2018 IPR001498 Impact, N-terminal SMALA_RS34580 a220aabb35832e7c7833b653f6ef011a 208 SUPERFAMILY SSF54211 3 130 7.21E-41 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SMALA_RS34580 a220aabb35832e7c7833b653f6ef011a 208 TIGRFAM TIGR00257 IMPACT_YIGZ: uncharacterized protein, YigZ family 1 200 1.2E-56 T 29-03-2018 IPR015796 Impact family, bacterial/archaeal SMALA_RS34580 a220aabb35832e7c7833b653f6ef011a 208 Gene3D G3DSA:3.30.70.240 135 198 2.3E-20 T 29-03-2018 SMALA_RS34580 a220aabb35832e7c7833b653f6ef011a 208 Pfam PF09186 Domain of unknown function (DUF1949) 140 194 3.4E-13 T 29-03-2018 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal SMALA_RS07400 4ffbf6b51ca8938b23235cf12b36bfa5 475 Gene3D G3DSA:3.20.20.120 197 454 4.2E-69 T 29-03-2018 IPR029065 Enolase C-terminal domain-like SMALA_RS07400 4ffbf6b51ca8938b23235cf12b36bfa5 475 SUPERFAMILY SSF54826 19 156 1.46E-34 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMALA_RS07400 4ffbf6b51ca8938b23235cf12b36bfa5 475 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 262 293 - T 29-03-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 SMALA_RS07400 4ffbf6b51ca8938b23235cf12b36bfa5 475 Pfam PF13378 Enolase C-terminal domain-like 219 431 2.1E-62 T 29-03-2018 IPR029065 Enolase C-terminal domain-like SMALA_RS07400 4ffbf6b51ca8938b23235cf12b36bfa5 475 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 49 153 7.7E-7 T 29-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain SMALA_RS07400 4ffbf6b51ca8938b23235cf12b36bfa5 475 Gene3D G3DSA:3.30.390.10 13 196 1.6E-41 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMALA_RS07400 4ffbf6b51ca8938b23235cf12b36bfa5 475 SMART SM00922 216 312 8.1E-28 T 29-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal SMALA_RS07400 4ffbf6b51ca8938b23235cf12b36bfa5 475 SUPERFAMILY SSF51604 201 446 1.07E-70 T 29-03-2018 IPR029065 Enolase C-terminal domain-like SMALA_RS17930 f079405569719f77c05043d31b9dcb3d 283 Pfam PF13560 Helix-turn-helix domain 13 76 1.1E-11 T 29-03-2018 SMALA_RS17930 f079405569719f77c05043d31b9dcb3d 283 Gene3D G3DSA:1.10.260.40 3 81 4.9E-14 T 29-03-2018 SMALA_RS17930 f079405569719f77c05043d31b9dcb3d 283 SMART SM00530 17 72 2.6E-7 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS17930 f079405569719f77c05043d31b9dcb3d 283 SUPERFAMILY SSF47413 10 75 1.21E-11 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS11850 9c89569f3f631fc5a718c864d2c0aa09 350 SUPERFAMILY SSF53335 6 177 1.51E-24 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS11850 9c89569f3f631fc5a718c864d2c0aa09 350 Gene3D G3DSA:3.40.50.150 4 148 7.3E-18 T 29-03-2018 SMALA_RS11850 9c89569f3f631fc5a718c864d2c0aa09 350 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 28 147 1.5E-21 T 29-03-2018 SMALA_RS16125 d4c2efe627f078c450a02a795aa5c848 459 Gene3D G3DSA:3.30.300.30 363 459 1.9E-27 T 29-03-2018 SMALA_RS16125 d4c2efe627f078c450a02a795aa5c848 459 Gene3D G3DSA:3.40.50.980 2 138 4.3E-25 T 29-03-2018 SMALA_RS16125 d4c2efe627f078c450a02a795aa5c848 459 Gene3D G3DSA:3.40.50.980 139 282 2.8E-40 T 29-03-2018 SMALA_RS16125 d4c2efe627f078c450a02a795aa5c848 459 ProSitePatterns PS00455 Putative AMP-binding domain signature. 133 144 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS16125 d4c2efe627f078c450a02a795aa5c848 459 SUPERFAMILY SSF56801 19 457 1.09E-118 T 29-03-2018 SMALA_RS16125 d4c2efe627f078c450a02a795aa5c848 459 Pfam PF13193 AMP-binding enzyme C-terminal domain 378 450 1.5E-20 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS16125 d4c2efe627f078c450a02a795aa5c848 459 Pfam PF00501 AMP-binding enzyme 22 369 3.7E-70 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS16125 d4c2efe627f078c450a02a795aa5c848 459 Gene3D G3DSA:2.30.38.10 283 361 2.3E-24 T 29-03-2018 SMALA_RS38840 25b7a28335b4b2bbd7a22770278e9ba9 295 Gene3D G3DSA:3.40.710.10 54 286 3.0E-18 T 29-03-2018 SMALA_RS38840 25b7a28335b4b2bbd7a22770278e9ba9 295 Pfam PF13354 Beta-lactamase enzyme family 124 239 4.0E-10 T 29-03-2018 SMALA_RS38840 25b7a28335b4b2bbd7a22770278e9ba9 295 SUPERFAMILY SSF56601 56 286 4.51E-35 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMALA_RS28215 b32d609c56762b4ad6fd2e5fee7d0bfd 179 Pfam PF00440 Bacterial regulatory proteins, tetR family 6 52 2.4E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS28215 b32d609c56762b4ad6fd2e5fee7d0bfd 179 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 6 19 4.2E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS28215 b32d609c56762b4ad6fd2e5fee7d0bfd 179 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 50 4.2E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS28215 b32d609c56762b4ad6fd2e5fee7d0bfd 179 SUPERFAMILY SSF48498 73 178 3.15E-5 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS28215 b32d609c56762b4ad6fd2e5fee7d0bfd 179 Gene3D G3DSA:1.10.10.60 1 49 3.1E-12 T 29-03-2018 SMALA_RS28215 b32d609c56762b4ad6fd2e5fee7d0bfd 179 SUPERFAMILY SSF46689 3 73 2.19E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS28215 b32d609c56762b4ad6fd2e5fee7d0bfd 179 Gene3D G3DSA:1.10.357.10 50 179 1.2E-11 T 29-03-2018 SMALA_RS20595 46afbd83982906544770e6c0ccd0124d 472 Gene3D G3DSA:1.10.10.10 397 467 0.0031 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS20595 46afbd83982906544770e6c0ccd0124d 472 Pfam PF13749 Putative ATP-dependent DNA helicase recG C-terminal 309 394 2.5E-18 T 29-03-2018 IPR025831 ATP-dependent DNA helicase RecG, C-terminal domain SMALA_RS20595 46afbd83982906544770e6c0ccd0124d 472 Pfam PF04326 Putative DNA-binding domain 19 137 1.2E-12 T 29-03-2018 IPR007421 Schlafen, AAA domain GO:0005524 SMALA_RS16360 af2816c53c287528f2af81b57f20bf6a 582 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 537 554 - T 29-03-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SMALA_RS16360 af2816c53c287528f2af81b57f20bf6a 582 Gene3D G3DSA:3.40.50.20 1 122 1.5E-49 T 29-03-2018 SMALA_RS16360 af2816c53c287528f2af81b57f20bf6a 582 SUPERFAMILY SSF51246 328 444 1.26E-36 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 SMALA_RS16360 af2816c53c287528f2af81b57f20bf6a 582 SMART SM00878 333 441 1.2E-55 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SMALA_RS16360 af2816c53c287528f2af81b57f20bf6a 582 Pfam PF00364 Biotin-requiring enzyme 515 580 2.1E-17 T 29-03-2018 IPR000089 Biotin/lipoyl attachment SMALA_RS16360 af2816c53c287528f2af81b57f20bf6a 582 Pfam PF02785 Biotin carboxylase C-terminal domain 333 441 4.5E-36 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SMALA_RS16360 af2816c53c287528f2af81b57f20bf6a 582 SUPERFAMILY SSF56059 114 321 6.72E-59 T 29-03-2018 SMALA_RS16360 af2816c53c287528f2af81b57f20bf6a 582 SUPERFAMILY SSF51230 509 580 1.57E-19 T 29-03-2018 IPR011053 Single hybrid motif SMALA_RS16360 af2816c53c287528f2af81b57f20bf6a 582 Gene3D G3DSA:2.40.50.100 512 582 1.1E-17 T 29-03-2018 SMALA_RS16360 af2816c53c287528f2af81b57f20bf6a 582 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 114 319 2.9E-75 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SMALA_RS16360 af2816c53c287528f2af81b57f20bf6a 582 SUPERFAMILY SSF52440 2 112 7.19E-46 T 29-03-2018 IPR016185 Pre-ATP-grasp domain SMALA_RS16360 af2816c53c287528f2af81b57f20bf6a 582 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 109 1.7E-43 T 29-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SMALA_RS16360 af2816c53c287528f2af81b57f20bf6a 582 Gene3D G3DSA:3.30.470.20 209 444 3.7E-92 T 29-03-2018 SMALA_RS16360 af2816c53c287528f2af81b57f20bf6a 582 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 285 292 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SMALA_RS16360 af2816c53c287528f2af81b57f20bf6a 582 Gene3D G3DSA:3.30.1490.20 123 208 2.9E-17 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SMALA_RS28260 2eb87332670030544751bfb549b1ab46 537 SUPERFAMILY SSF161098 2 248 1.44E-49 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS28260 2eb87332670030544751bfb549b1ab46 537 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 67 252 4.7E-15 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS28260 2eb87332670030544751bfb549b1ab46 537 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 350 522 1.6E-9 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS28260 2eb87332670030544751bfb549b1ab46 537 SUPERFAMILY SSF161098 270 531 9.81E-47 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS28260 2eb87332670030544751bfb549b1ab46 537 Gene3D G3DSA:1.10.3720.10 273 534 5.3E-35 T 29-03-2018 SMALA_RS28260 2eb87332670030544751bfb549b1ab46 537 Gene3D G3DSA:1.10.3720.10 1 258 1.6E-39 T 29-03-2018 SMALA_RS35875 f3a92041e54a70f611c51c903f14f2ee 382 Gene3D G3DSA:3.30.2110.10 25 198 7.6E-64 T 29-03-2018 SMALA_RS35875 f3a92041e54a70f611c51c903f14f2ee 382 SUPERFAMILY SSF111342 16 301 7.06E-84 T 29-03-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 SMALA_RS35875 f3a92041e54a70f611c51c903f14f2ee 382 Pfam PF01888 CbiD 23 283 2.3E-88 T 29-03-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 SMALA_RS35875 f3a92041e54a70f611c51c903f14f2ee 382 Hamap MF_00787 Cobalt-precorrin-5B C(1)-methyltransferase [cbiD]. 23 374 27.695 T 29-03-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 SMALA_RS35875 f3a92041e54a70f611c51c903f14f2ee 382 PIRSF PIRSF026782 19 379 4.8E-127 T 29-03-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 SMALA_RS35875 f3a92041e54a70f611c51c903f14f2ee 382 TIGRFAM TIGR00312 cbiD: cobalamin biosynthesis protein CbiD 30 334 1.6E-51 T 29-03-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 SMALA_RS25115 1211d611b496e09bfe85f032afdce124 273 SMART SM01007 44 224 2.2E-59 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal SMALA_RS25115 1211d611b496e09bfe85f032afdce124 273 SUPERFAMILY SSF53639 37 255 1.0E-65 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal SMALA_RS25115 1211d611b496e09bfe85f032afdce124 273 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 44 224 1.9E-46 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal SMALA_RS25115 1211d611b496e09bfe85f032afdce124 273 Gene3D G3DSA:3.40.225.10 30 267 2.5E-66 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal SMALA_RS14055 67b0723907ab1ae81686a4a6f1fa48d7 127 Gene3D G3DSA:3.10.180.10 2 125 1.2E-21 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS14055 67b0723907ab1ae81686a4a6f1fa48d7 127 SUPERFAMILY SSF54593 1 120 3.66E-15 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS40685 8ac7567ab650933f24441e15d77e77bf 286 Gene3D G3DSA:3.90.850.10 34 285 7.2E-73 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 SMALA_RS40685 8ac7567ab650933f24441e15d77e77bf 286 SUPERFAMILY SSF56529 61 283 1.7E-68 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 SMALA_RS40685 8ac7567ab650933f24441e15d77e77bf 286 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 75 280 1.6E-63 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 SMALA_RS29785 9f44e862b3244eaf6e32d3bb5cf608a9 366 Pfam PF13407 Periplasmic binding protein domain 51 306 4.8E-61 T 29-03-2018 IPR025997 Periplasmic binding protein SMALA_RS29785 9f44e862b3244eaf6e32d3bb5cf608a9 366 SUPERFAMILY SSF53822 44 339 1.49E-61 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SMALA_RS29785 9f44e862b3244eaf6e32d3bb5cf608a9 366 Gene3D G3DSA:3.40.50.2300 160 319 9.1E-26 T 29-03-2018 SMALA_RS29785 9f44e862b3244eaf6e32d3bb5cf608a9 366 Gene3D G3DSA:3.40.50.2300 38 159 8.3E-20 T 29-03-2018 SMALA_RS16675 fea333447aa2c27320362c8a97c46bb8 548 Pfam PF02838 Glycosyl hydrolase family 20, domain 2 77 192 2.0E-13 T 29-03-2018 IPR015882 Beta-hexosaminidase, bacteial type, N-terminal KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822 SMALA_RS16675 fea333447aa2c27320362c8a97c46bb8 548 Gene3D G3DSA:3.20.20.80 184 547 1.9E-79 T 29-03-2018 SMALA_RS16675 fea333447aa2c27320362c8a97c46bb8 548 PRINTS PR00738 Glycosyl hydrolase family 20 signature 190 207 4.1E-16 T 29-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMALA_RS16675 fea333447aa2c27320362c8a97c46bb8 548 PRINTS PR00738 Glycosyl hydrolase family 20 signature 331 344 4.1E-16 T 29-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMALA_RS16675 fea333447aa2c27320362c8a97c46bb8 548 PRINTS PR00738 Glycosyl hydrolase family 20 signature 267 284 4.1E-16 T 29-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMALA_RS16675 fea333447aa2c27320362c8a97c46bb8 548 PRINTS PR00738 Glycosyl hydrolase family 20 signature 491 507 4.1E-16 T 29-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMALA_RS16675 fea333447aa2c27320362c8a97c46bb8 548 PRINTS PR00738 Glycosyl hydrolase family 20 signature 158 178 4.1E-16 T 29-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMALA_RS16675 fea333447aa2c27320362c8a97c46bb8 548 SUPERFAMILY SSF55545 71 194 6.8E-15 T 29-03-2018 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMALA_RS16675 fea333447aa2c27320362c8a97c46bb8 548 SUPERFAMILY SSF51445 198 542 2.28E-75 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS16675 fea333447aa2c27320362c8a97c46bb8 548 Pfam PF00728 Glycosyl hydrolase family 20, catalytic domain 199 528 1.1E-42 T 29-03-2018 IPR015883 Glycoside hydrolase family 20, catalytic domain GO:0004553|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822 SMALA_RS16675 fea333447aa2c27320362c8a97c46bb8 548 Gene3D G3DSA:3.30.379.10 64 183 2.0E-14 T 29-03-2018 SMALA_RS03945 052c2d80ca94a9c1bc1ac25fa781ac4a 169 Pfam PF14539 Domain of unknown function (DUF4442) 10 143 2.0E-18 T 29-03-2018 IPR027961 Protein of unknown function DUF4442 SMALA_RS03945 052c2d80ca94a9c1bc1ac25fa781ac4a 169 Gene3D G3DSA:3.10.129.10 1 146 1.1E-22 T 29-03-2018 SMALA_RS03945 052c2d80ca94a9c1bc1ac25fa781ac4a 169 SUPERFAMILY SSF54637 6 144 3.18E-25 T 29-03-2018 IPR029069 HotDog domain SMALA_RS39010 53a4b2012ddbdcc4f47c968b325a0a2b 260 Gene3D G3DSA:3.40.50.10310 14 255 5.1E-59 T 29-03-2018 IPR024087 Creatininase-like domain KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167 SMALA_RS39010 53a4b2012ddbdcc4f47c968b325a0a2b 260 Pfam PF02633 Creatinine amidohydrolase 21 236 2.2E-52 T 29-03-2018 IPR003785 Creatininase/formamide hydrolase KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167 SMALA_RS39010 53a4b2012ddbdcc4f47c968b325a0a2b 260 SUPERFAMILY SSF102215 19 241 1.1E-49 T 29-03-2018 IPR024087 Creatininase-like domain KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167 SMALA_RS11045 b100ed6f6458452f66171c3d46ad8137 435 Gene3D G3DSA:1.20.1250.20 233 426 7.6E-17 T 29-03-2018 SMALA_RS11045 b100ed6f6458452f66171c3d46ad8137 435 Gene3D G3DSA:1.20.1250.20 28 224 2.6E-19 T 29-03-2018 SMALA_RS11045 b100ed6f6458452f66171c3d46ad8137 435 Pfam PF05977 Transmembrane secretion effector 26 426 3.5E-30 T 29-03-2018 IPR010290 Transmembrane secretion effector SMALA_RS11045 b100ed6f6458452f66171c3d46ad8137 435 SUPERFAMILY SSF103473 32 419 2.62E-42 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS26475 04a25ae8fcd31355ba19fbdb734d46a5 312 Gene3D G3DSA:1.10.3720.10 26 286 8.2E-51 T 29-03-2018 SMALA_RS26475 04a25ae8fcd31355ba19fbdb734d46a5 312 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 67 175 2.6E-18 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 SMALA_RS26475 04a25ae8fcd31355ba19fbdb734d46a5 312 SUPERFAMILY SSF161098 66 266 2.09E-44 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS26475 04a25ae8fcd31355ba19fbdb734d46a5 312 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 86 277 1.0E-23 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS26235 da3df0ae76837265189a559d5d0b07a2 282 SUPERFAMILY SSF81296 2 34 3.34E-9 T 29-03-2018 IPR014756 Immunoglobulin E-set SMALA_RS26235 da3df0ae76837265189a559d5d0b07a2 282 SUPERFAMILY SSF81296 68 107 3.34E-9 T 29-03-2018 IPR014756 Immunoglobulin E-set SMALA_RS26235 da3df0ae76837265189a559d5d0b07a2 282 Gene3D G3DSA:2.60.40.10 200 281 6.9E-14 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS26235 da3df0ae76837265189a559d5d0b07a2 282 SMART SM00429 111 196 1.3E-4 T 29-03-2018 IPR002909 IPT domain SMALA_RS26235 da3df0ae76837265189a559d5d0b07a2 282 SMART SM00429 201 282 2.7E-5 T 29-03-2018 IPR002909 IPT domain SMALA_RS26235 da3df0ae76837265189a559d5d0b07a2 282 SMART SM00429 1 107 0.84 T 29-03-2018 IPR002909 IPT domain SMALA_RS26235 da3df0ae76837265189a559d5d0b07a2 282 Gene3D G3DSA:2.60.40.10 105 196 1.0E-13 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS26235 da3df0ae76837265189a559d5d0b07a2 282 SUPERFAMILY SSF81296 200 282 1.4E-9 T 29-03-2018 IPR014756 Immunoglobulin E-set SMALA_RS26235 da3df0ae76837265189a559d5d0b07a2 282 Gene3D G3DSA:2.60.40.10 1 104 4.9E-16 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS26235 da3df0ae76837265189a559d5d0b07a2 282 SUPERFAMILY SSF81296 110 195 1.4E-8 T 29-03-2018 IPR014756 Immunoglobulin E-set SMALA_RS26235 da3df0ae76837265189a559d5d0b07a2 282 Pfam PF01833 IPT/TIG domain 202 272 8.3E-9 T 29-03-2018 IPR002909 IPT domain SMALA_RS26235 da3df0ae76837265189a559d5d0b07a2 282 Pfam PF01833 IPT/TIG domain 2 106 1.9E-9 T 29-03-2018 IPR002909 IPT domain SMALA_RS26235 da3df0ae76837265189a559d5d0b07a2 282 Pfam PF01833 IPT/TIG domain 112 195 2.3E-9 T 29-03-2018 IPR002909 IPT domain SMALA_RS38610 e026e3ff2bc881388382e11192f0366f 370 SUPERFAMILY SSF51604 118 347 9.04E-58 T 29-03-2018 IPR029065 Enolase C-terminal domain-like SMALA_RS38610 e026e3ff2bc881388382e11192f0366f 370 Hamap MF_01933 o-succinylbenzoate synthase [menC]. 2 361 37.649 T 29-03-2018 IPR010197 o-Succinylbenzoate synthase, MenC type 2 GO:0009234|GO:0016829 KEGG: 00010+4.2.1.11|KEGG: 00130+4.2.1.113|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-5837|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMALA_RS38610 e026e3ff2bc881388382e11192f0366f 370 Gene3D G3DSA:3.20.20.120 128 348 3.0E-53 T 29-03-2018 IPR029065 Enolase C-terminal domain-like SMALA_RS38610 e026e3ff2bc881388382e11192f0366f 370 Pfam PF13378 Enolase C-terminal domain-like 157 347 3.8E-39 T 29-03-2018 IPR029065 Enolase C-terminal domain-like SMALA_RS38610 e026e3ff2bc881388382e11192f0366f 370 Gene3D G3DSA:3.30.390.10 1 127 4.6E-27 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMALA_RS38610 e026e3ff2bc881388382e11192f0366f 370 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 10 126 3.0E-11 T 29-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain SMALA_RS38610 e026e3ff2bc881388382e11192f0366f 370 SMART SM00922 142 237 1.9E-19 T 29-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal SMALA_RS38610 e026e3ff2bc881388382e11192f0366f 370 SUPERFAMILY SSF54826 3 127 6.59E-28 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMALA_RS38610 e026e3ff2bc881388382e11192f0366f 370 TIGRFAM TIGR01928 menC_lowGC/arch: o-succinylbenzoate synthase 10 335 1.7E-89 T 29-03-2018 IPR010197 o-Succinylbenzoate synthase, MenC type 2 GO:0009234|GO:0016829 KEGG: 00010+4.2.1.11|KEGG: 00130+4.2.1.113|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-5837|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMALA_RS36380 379f682494f14c0cb11c3d314b76c91b 143 Gene3D G3DSA:2.30.110.10 2 143 1.3E-26 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS36380 379f682494f14c0cb11c3d314b76c91b 143 TIGRFAM TIGR03668 Rv0121_F420: PPOX class probable F420-dependent enzyme, Rv0121 family 7 141 7.2E-49 T 29-03-2018 IPR019967 F420-dependent enzyme, PPOX class, family Rv0121, probable SMALA_RS36380 379f682494f14c0cb11c3d314b76c91b 143 SUPERFAMILY SSF50475 3 141 1.55E-25 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS36380 379f682494f14c0cb11c3d314b76c91b 143 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 7 100 2.8E-13 T 29-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 SMALA_RS02440 d98faa9d732677fc40e515cf19a958d2 243 Gene3D G3DSA:3.40.50.150 9 241 1.1E-28 T 29-03-2018 SMALA_RS02440 d98faa9d732677fc40e515cf19a958d2 243 Pfam PF13649 Methyltransferase domain 60 155 3.8E-19 T 29-03-2018 SMALA_RS02440 d98faa9d732677fc40e515cf19a958d2 243 SUPERFAMILY SSF53335 11 220 3.16E-34 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS12685 61b09ca55bad6eee5d933bfefc90e95f 401 SUPERFAMILY SSF55874 287 398 3.92E-12 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS12685 61b09ca55bad6eee5d933bfefc90e95f 401 Gene3D G3DSA:3.30.565.10 191 400 3.7E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS12685 61b09ca55bad6eee5d933bfefc90e95f 401 Pfam PF07730 Histidine kinase 211 278 3.0E-16 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMALA_RS01200 d6720d51563966a5661d364bb0f6bebc 150 SUPERFAMILY SSF54593 11 144 7.38E-24 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS01200 d6720d51563966a5661d364bb0f6bebc 150 Gene3D G3DSA:3.10.180.10 11 145 6.2E-21 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS01200 d6720d51563966a5661d364bb0f6bebc 150 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 12 138 4.2E-8 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMALA_RS11255 75bac8e6e71365a6645f491cf1055e85 609 ProSitePatterns PS00888 Cyclic nucleotide-binding domain signature 1. 53 69 - T 29-03-2018 IPR018488 Cyclic nucleotide-binding, conserved site SMALA_RS11255 75bac8e6e71365a6645f491cf1055e85 609 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 473 494 3.4E-34 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMALA_RS11255 75bac8e6e71365a6645f491cf1055e85 609 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 381 405 3.4E-34 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMALA_RS11255 75bac8e6e71365a6645f491cf1055e85 609 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 242 264 3.4E-34 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMALA_RS11255 75bac8e6e71365a6645f491cf1055e85 609 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 275 290 3.4E-34 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMALA_RS11255 75bac8e6e71365a6645f491cf1055e85 609 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 435 451 3.4E-34 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMALA_RS11255 75bac8e6e71365a6645f491cf1055e85 609 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 343 351 3.4E-34 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMALA_RS11255 75bac8e6e71365a6645f491cf1055e85 609 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 242 552 5.8E-29 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS11255 75bac8e6e71365a6645f491cf1055e85 609 Pfam PF00027 Cyclic nucleotide-binding domain 45 131 3.3E-16 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain SMALA_RS11255 75bac8e6e71365a6645f491cf1055e85 609 SMART SM00100 26 144 1.2E-16 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain SMALA_RS11255 75bac8e6e71365a6645f491cf1055e85 609 Gene3D G3DSA:2.60.120.10 26 160 2.3E-19 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SMALA_RS11255 75bac8e6e71365a6645f491cf1055e85 609 Gene3D G3DSA:3.50.50.60 240 377 7.9E-21 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS11255 75bac8e6e71365a6645f491cf1055e85 609 SUPERFAMILY SSF51905 227 563 4.8E-36 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS11255 75bac8e6e71365a6645f491cf1055e85 609 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 516 538 6.2E-25 T 29-03-2018 SMALA_RS11255 75bac8e6e71365a6645f491cf1055e85 609 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 342 360 6.2E-25 T 29-03-2018 SMALA_RS11255 75bac8e6e71365a6645f491cf1055e85 609 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 471 487 6.2E-25 T 29-03-2018 SMALA_RS11255 75bac8e6e71365a6645f491cf1055e85 609 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 385 403 6.2E-25 T 29-03-2018 SMALA_RS11255 75bac8e6e71365a6645f491cf1055e85 609 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 243 262 6.2E-25 T 29-03-2018 SMALA_RS11255 75bac8e6e71365a6645f491cf1055e85 609 SUPERFAMILY SSF51206 29 150 2.36E-23 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like SMALA_RS11255 75bac8e6e71365a6645f491cf1055e85 609 Gene3D G3DSA:3.50.50.60 386 570 5.9E-22 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS38545 8ff488e9021291c40df7125ced8cf98f 492 SUPERFAMILY SSF53720 13 489 7.2E-158 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMALA_RS38545 8ff488e9021291c40df7125ced8cf98f 492 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 261 268 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 SMALA_RS38545 8ff488e9021291c40df7125ced8cf98f 492 Gene3D G3DSA:3.40.309.10 280 471 5.1E-68 T 29-03-2018 SMALA_RS38545 8ff488e9021291c40df7125ced8cf98f 492 Gene3D G3DSA:3.40.605.10 14 279 4.1E-96 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS38545 8ff488e9021291c40df7125ced8cf98f 492 Pfam PF00171 Aldehyde dehydrogenase family 25 484 1.0E-156 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS11520 066065c71544cbc475fd79f0196cc967 274 Pfam PF12833 Helix-turn-helix domain 185 262 6.4E-22 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS11520 066065c71544cbc475fd79f0196cc967 274 Gene3D G3DSA:1.10.10.60 216 269 7.2E-13 T 29-03-2018 SMALA_RS11520 066065c71544cbc475fd79f0196cc967 274 Gene3D G3DSA:1.10.10.60 114 215 1.6E-12 T 29-03-2018 SMALA_RS11520 066065c71544cbc475fd79f0196cc967 274 SMART SM00342 179 261 6.1E-24 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS11520 066065c71544cbc475fd79f0196cc967 274 SUPERFAMILY SSF51215 7 124 6.8E-20 T 29-03-2018 SMALA_RS11520 066065c71544cbc475fd79f0196cc967 274 SUPERFAMILY SSF46689 165 213 1.42E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS11520 066065c71544cbc475fd79f0196cc967 274 SUPERFAMILY SSF46689 215 263 4.93E-10 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS11520 066065c71544cbc475fd79f0196cc967 274 Pfam PF02311 AraC-like ligand binding domain 3 134 4.3E-19 T 29-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 SMALA_RS12700 95243d9ccd4d86c4087c59db4643f782 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 137 149 6.6E-50 T 29-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 SMALA_RS12700 95243d9ccd4d86c4087c59db4643f782 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 403 422 6.6E-50 T 29-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 SMALA_RS12700 95243d9ccd4d86c4087c59db4643f782 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 317 329 6.6E-50 T 29-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 SMALA_RS12700 95243d9ccd4d86c4087c59db4643f782 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 25 39 6.6E-50 T 29-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 SMALA_RS12700 95243d9ccd4d86c4087c59db4643f782 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 190 207 6.6E-50 T 29-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 SMALA_RS12700 95243d9ccd4d86c4087c59db4643f782 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 207 217 6.6E-50 T 29-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 SMALA_RS12700 95243d9ccd4d86c4087c59db4643f782 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 158 175 6.6E-50 T 29-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 SMALA_RS12700 95243d9ccd4d86c4087c59db4643f782 460 Gene3D G3DSA:3.30.930.10 113 223 1.6E-31 T 29-03-2018 SMALA_RS12700 95243d9ccd4d86c4087c59db4643f782 460 Gene3D G3DSA:3.30.930.10 3 112 2.5E-19 T 29-03-2018 SMALA_RS12700 95243d9ccd4d86c4087c59db4643f782 460 Gene3D G3DSA:3.30.930.10 224 357 1.8E-41 T 29-03-2018 SMALA_RS12700 95243d9ccd4d86c4087c59db4643f782 460 Hamap MF_00253_B Glycine--tRNA ligase [glyQS]. 3 458 49.185 T 29-03-2018 IPR022961 Glycine-tRNA ligase, bacterial GO:0004820 KEGG: 00970+6.1.1.14 SMALA_RS12700 95243d9ccd4d86c4087c59db4643f782 460 Gene3D G3DSA:3.40.50.800 358 457 8.7E-27 T 29-03-2018 IPR004154 Anticodon-binding SMALA_RS12700 95243d9ccd4d86c4087c59db4643f782 460 TIGRFAM TIGR00389 glyS_dimeric: glycine--tRNA ligase 6 234 1.5E-79 T 29-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 SMALA_RS12700 95243d9ccd4d86c4087c59db4643f782 460 SUPERFAMILY SSF55681 5 369 9.5E-119 T 29-03-2018 SMALA_RS12700 95243d9ccd4d86c4087c59db4643f782 460 Pfam PF03129 Anticodon binding domain 366 453 3.1E-22 T 29-03-2018 IPR004154 Anticodon-binding SMALA_RS12700 95243d9ccd4d86c4087c59db4643f782 460 SUPERFAMILY SSF52954 353 455 1.01E-33 T 29-03-2018 IPR004154 Anticodon-binding SMALA_RS12700 95243d9ccd4d86c4087c59db4643f782 460 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 157 333 1.7E-9 T 29-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMALA_RS36520 8c18d46ea90f6bdf173e0f074e9ffa6b 253 Gene3D G3DSA:3.20.10.10 97 243 1.3E-24 T 29-03-2018 SMALA_RS36520 8c18d46ea90f6bdf173e0f074e9ffa6b 253 Pfam PF01063 Amino-transferase class IV 23 225 4.7E-23 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 SMALA_RS36520 8c18d46ea90f6bdf173e0f074e9ffa6b 253 SUPERFAMILY SSF56752 24 234 1.14E-29 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 SMALA_RS36745 c8e6a3d7cc70c54d4467185c033d6672 476 SUPERFAMILY SSF51905 304 355 4.66E-27 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS36745 c8e6a3d7cc70c54d4467185c033d6672 476 SUPERFAMILY SSF51905 4 190 4.66E-27 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS36745 c8e6a3d7cc70c54d4467185c033d6672 476 Gene3D G3DSA:3.50.50.60 8 380 4.5E-26 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS36745 c8e6a3d7cc70c54d4467185c033d6672 476 Pfam PF12831 FAD dependent oxidoreductase 8 176 2.6E-7 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS26970 6038cbcb786549b0f76d2650eb86e462 282 SUPERFAMILY SSF48179 186 282 1.11E-27 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMALA_RS26970 6038cbcb786549b0f76d2650eb86e462 282 Gene3D G3DSA:1.10.1040.10 184 282 1.8E-30 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMALA_RS26970 6038cbcb786549b0f76d2650eb86e462 282 PIRSF PIRSF000105 1 282 3.6E-91 T 29-03-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 SMALA_RS26970 6038cbcb786549b0f76d2650eb86e462 282 Gene3D G3DSA:3.40.50.720 1 183 2.1E-62 T 29-03-2018 SMALA_RS26970 6038cbcb786549b0f76d2650eb86e462 282 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 4 183 1.2E-68 T 29-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 SMALA_RS26970 6038cbcb786549b0f76d2650eb86e462 282 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 183 208 - T 29-03-2018 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 SMALA_RS26970 6038cbcb786549b0f76d2650eb86e462 282 SUPERFAMILY SSF51735 3 182 1.29E-61 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS26970 6038cbcb786549b0f76d2650eb86e462 282 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 186 282 5.9E-31 T 29-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 SMALA_RS00305 c046b9a790f3d424df84aa7336c445dc 403 Gene3D G3DSA:3.40.50.80 259 397 2.6E-20 T 29-03-2018 SMALA_RS00305 c046b9a790f3d424df84aa7336c445dc 403 Gene3D G3DSA:2.40.30.10 163 258 8.2E-25 T 29-03-2018 SMALA_RS00305 c046b9a790f3d424df84aa7336c445dc 403 Gene3D G3DSA:1.10.490.10 1 162 3.2E-33 T 29-03-2018 SMALA_RS00305 c046b9a790f3d424df84aa7336c445dc 403 SUPERFAMILY SSF46458 1 137 9.31E-32 T 29-03-2018 IPR009050 Globin-like SMALA_RS00305 c046b9a790f3d424df84aa7336c445dc 403 PRINTS PR00410 Phenol hydroxylase reductase family signature 357 365 5.4E-7 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 SMALA_RS00305 c046b9a790f3d424df84aa7336c445dc 403 PRINTS PR00410 Phenol hydroxylase reductase family signature 269 288 5.4E-7 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 SMALA_RS00305 c046b9a790f3d424df84aa7336c445dc 403 PRINTS PR00410 Phenol hydroxylase reductase family signature 186 198 5.4E-7 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 SMALA_RS00305 c046b9a790f3d424df84aa7336c445dc 403 Pfam PF00175 Oxidoreductase NAD-binding domain 272 371 5.6E-9 T 29-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 SMALA_RS00305 c046b9a790f3d424df84aa7336c445dc 403 SUPERFAMILY SSF63380 154 260 9.5E-28 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 SMALA_RS00305 c046b9a790f3d424df84aa7336c445dc 403 Pfam PF00970 Oxidoreductase FAD-binding domain 159 258 1.3E-9 T 29-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 SMALA_RS00305 c046b9a790f3d424df84aa7336c445dc 403 SUPERFAMILY SSF52343 263 391 7.07E-31 T 29-03-2018 SMALA_RS00305 c046b9a790f3d424df84aa7336c445dc 403 Pfam PF00042 Globin 8 104 3.0E-6 T 29-03-2018 IPR000971 Globin GO:0020037 SMALA_RS39055 948880906b523c979305d71666f451a8 157 Gene3D G3DSA:1.10.10.10 7 156 6.8E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS39055 948880906b523c979305d71666f451a8 157 SUPERFAMILY SSF46785 17 152 3.79E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS39055 948880906b523c979305d71666f451a8 157 Pfam PF01638 HxlR-like helix-turn-helix 24 113 1.6E-20 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type SMALA_RS30985 f5969f74605f4552463e4b17da58fbef 127 Gene3D G3DSA:3.10.580.10 2 126 4.2E-28 T 29-03-2018 SMALA_RS30985 f5969f74605f4552463e4b17da58fbef 127 SUPERFAMILY SSF54631 7 125 3.79E-32 T 29-03-2018 SMALA_RS30985 f5969f74605f4552463e4b17da58fbef 127 Pfam PF00571 CBS domain 76 125 1.3E-13 T 29-03-2018 IPR000644 CBS domain SMALA_RS30985 f5969f74605f4552463e4b17da58fbef 127 Pfam PF00571 CBS domain 9 59 4.6E-12 T 29-03-2018 IPR000644 CBS domain SMALA_RS30985 f5969f74605f4552463e4b17da58fbef 127 SMART SM00116 16 63 7.9E-6 T 29-03-2018 IPR000644 CBS domain SMALA_RS30985 f5969f74605f4552463e4b17da58fbef 127 SMART SM00116 81 126 1.0E-5 T 29-03-2018 IPR000644 CBS domain SMALA_RS20495 0bf04656289caead7b9dc72b625a2e0e 333 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS20495 0bf04656289caead7b9dc72b625a2e0e 333 SUPERFAMILY SSF46955 1 112 2.2E-23 T 29-03-2018 IPR009061 Putative DNA-binding domain SMALA_RS20495 0bf04656289caead7b9dc72b625a2e0e 333 Gene3D G3DSA:3.40.30.10 144 330 4.2E-21 T 29-03-2018 SMALA_RS20495 0bf04656289caead7b9dc72b625a2e0e 333 SUPERFAMILY SSF52833 152 329 3.22E-23 T 29-03-2018 IPR012336 Thioredoxin-like fold SMALA_RS20495 0bf04656289caead7b9dc72b625a2e0e 333 Pfam PF08534 Redoxin 194 325 3.0E-19 T 29-03-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 SMALA_RS20495 0bf04656289caead7b9dc72b625a2e0e 333 Gene3D G3DSA:1.10.1660.10 55 132 1.6E-10 T 29-03-2018 SMALA_RS20495 0bf04656289caead7b9dc72b625a2e0e 333 SMART SM00422 1 69 2.5E-23 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS20495 0bf04656289caead7b9dc72b625a2e0e 333 Pfam PF13411 MerR HTH family regulatory protein 1 62 1.8E-15 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS20495 0bf04656289caead7b9dc72b625a2e0e 333 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 4.2E-10 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS20495 0bf04656289caead7b9dc72b625a2e0e 333 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 4.2E-10 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS20495 0bf04656289caead7b9dc72b625a2e0e 333 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 4.2E-10 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS20495 0bf04656289caead7b9dc72b625a2e0e 333 Gene3D G3DSA:1.10.1660.10 1 54 8.3E-21 T 29-03-2018 SMALA_RS29000 4eb89ff2b31af15ea1fc91c1ee5483fb 233 Pfam PF01351 Ribonuclease HII 24 200 1.5E-34 T 29-03-2018 IPR024567 Ribonuclease HII/HIII domain SMALA_RS29000 4eb89ff2b31af15ea1fc91c1ee5483fb 233 Gene3D G3DSA:3.30.420.10 4 223 4.1E-60 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SMALA_RS29000 4eb89ff2b31af15ea1fc91c1ee5483fb 233 Hamap MF_00052_B Ribonuclease HII [rnhB]. 22 202 34.869 T 29-03-2018 IPR022898 Ribonuclease HII GO:0004523 SMALA_RS29000 4eb89ff2b31af15ea1fc91c1ee5483fb 233 SUPERFAMILY SSF53098 18 208 5.77E-55 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SMALA_RS41280 2667a4a4d06807548e5334334ab796e2 155 Gene3D G3DSA:3.90.80.10 17 119 1.8E-5 T 29-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 SMALA_RS41280 2667a4a4d06807548e5334334ab796e2 155 Pfam PF00719 Inorganic pyrophosphatase 35 107 3.3E-6 T 29-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 SMALA_RS41280 2667a4a4d06807548e5334334ab796e2 155 SUPERFAMILY SSF50324 35 104 3.79E-9 T 29-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 SMALA_RS09600 3d0df04ac8c9233daa9f0119068c06d4 311 Gene3D G3DSA:3.40.50.300 17 185 2.3E-12 T 29-03-2018 SMALA_RS09600 3d0df04ac8c9233daa9f0119068c06d4 311 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 28 310 41.399 T 29-03-2018 IPR005337 RapZ-like family GO:0005524 SMALA_RS09600 3d0df04ac8c9233daa9f0119068c06d4 311 Pfam PF03668 P-loop ATPase protein family 29 311 9.6E-112 T 29-03-2018 IPR005337 RapZ-like family GO:0005524 SMALA_RS09600 3d0df04ac8c9233daa9f0119068c06d4 311 SUPERFAMILY SSF52540 29 181 2.84E-14 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS09600 3d0df04ac8c9233daa9f0119068c06d4 311 PIRSF PIRSF005052 28 311 6.4E-112 T 29-03-2018 IPR005337 RapZ-like family GO:0005524 SMALA_RS35460 953d0d2b4823c0efb669de7958a38bc7 449 Gene3D G3DSA:3.40.190.10 171 350 2.8E-32 T 29-03-2018 SMALA_RS35460 953d0d2b4823c0efb669de7958a38bc7 449 SUPERFAMILY SSF53850 23 446 1.54E-72 T 29-03-2018 SMALA_RS35460 953d0d2b4823c0efb669de7958a38bc7 449 Pfam PF01547 Bacterial extracellular solute-binding protein 50 342 6.8E-49 T 29-03-2018 IPR006059 Solute-binding family 1 GO:0006810 SMALA_RS35460 953d0d2b4823c0efb669de7958a38bc7 449 Gene3D G3DSA:3.40.190.10 36 170 5.6E-21 T 29-03-2018 SMALA_RS16310 b09d9ad5c1749caaec458d0616ea47c0 514 TIGRFAM TIGR01225 hutH: histidine ammonia-lyase 6 508 3.0E-210 T 29-03-2018 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 SMALA_RS16310 b09d9ad5c1749caaec458d0616ea47c0 514 SUPERFAMILY SSF48557 5 504 4.08E-179 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 SMALA_RS16310 b09d9ad5c1749caaec458d0616ea47c0 514 Hamap MF_00229 Histidine ammonia-lyase [hutH]. 5 508 43.339 T 29-03-2018 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 SMALA_RS16310 b09d9ad5c1749caaec458d0616ea47c0 514 ProSitePatterns PS00488 Phenylalanine and histidine ammonia-lyases signature. 141 157 - T 29-03-2018 IPR022313 Phenylalanine/histidine ammonia-lyases, active site GO:0016841 Reactome: R-HSA-70921 SMALA_RS16310 b09d9ad5c1749caaec458d0616ea47c0 514 Pfam PF00221 Aromatic amino acid lyase 14 473 2.6E-182 T 29-03-2018 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 SMALA_RS16310 b09d9ad5c1749caaec458d0616ea47c0 514 Gene3D G3DSA:1.20.200.10 202 511 4.4E-114 T 29-03-2018 SMALA_RS16310 b09d9ad5c1749caaec458d0616ea47c0 514 Gene3D G3DSA:1.10.275.10 1 200 2.1E-72 T 29-03-2018 IPR024083 Fumarase/histidase, N-terminal SMALA_RS35025 392271deacf23af80b6f99d53ab02a7f 546 SUPERFAMILY SSF142764 7 253 8.89E-39 T 29-03-2018 SMALA_RS35025 392271deacf23af80b6f99d53ab02a7f 546 SUPERFAMILY SSF142764 299 344 8.89E-39 T 29-03-2018 SMALA_RS35025 392271deacf23af80b6f99d53ab02a7f 546 Pfam PF07005 Putative sugar-binding N-terminal domain 7 240 1.5E-36 T 29-03-2018 IPR010737 Putative sugar-binding, N-terminal domain SMALA_RS35025 392271deacf23af80b6f99d53ab02a7f 546 Gene3D G3DSA:3.40.50.10840 6 248 2.3E-48 T 29-03-2018 IPR010737 Putative sugar-binding, N-terminal domain SMALA_RS35025 392271deacf23af80b6f99d53ab02a7f 546 SUPERFAMILY SSF142764 451 535 1.83E-12 T 29-03-2018 SMALA_RS35025 392271deacf23af80b6f99d53ab02a7f 546 Pfam PF17042 Putative nucleotide-binding of sugar-metabolising enzyme 450 528 8.3E-12 T 29-03-2018 IPR031475 Putative nucleotide-binding C-terminal domain SMALA_RS07015 aa4d8d6a388a54ae676af143c08c272c 436 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 23 417 3.2E-133 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 SMALA_RS07015 aa4d8d6a388a54ae676af143c08c272c 436 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 219 251 - T 29-03-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 SMALA_RS07015 aa4d8d6a388a54ae676af143c08c272c 436 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 2 418 33.188 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 SMALA_RS07015 aa4d8d6a388a54ae676af143c08c272c 436 PIRSF PIRSF000099 3 421 5.5E-121 T 29-03-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 SMALA_RS07015 aa4d8d6a388a54ae676af143c08c272c 436 PRINTS PR00083 Histidinol dehydrogenase signature 190 215 8.1E-76 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 SMALA_RS07015 aa4d8d6a388a54ae676af143c08c272c 436 PRINTS PR00083 Histidinol dehydrogenase signature 310 335 8.1E-76 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 SMALA_RS07015 aa4d8d6a388a54ae676af143c08c272c 436 PRINTS PR00083 Histidinol dehydrogenase signature 219 240 8.1E-76 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 SMALA_RS07015 aa4d8d6a388a54ae676af143c08c272c 436 PRINTS PR00083 Histidinol dehydrogenase signature 241 260 8.1E-76 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 SMALA_RS07015 aa4d8d6a388a54ae676af143c08c272c 436 PRINTS PR00083 Histidinol dehydrogenase signature 23 47 8.1E-76 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 SMALA_RS07015 aa4d8d6a388a54ae676af143c08c272c 436 PRINTS PR00083 Histidinol dehydrogenase signature 98 125 8.1E-76 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 SMALA_RS07015 aa4d8d6a388a54ae676af143c08c272c 436 PRINTS PR00083 Histidinol dehydrogenase signature 351 369 8.1E-76 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 SMALA_RS07015 aa4d8d6a388a54ae676af143c08c272c 436 PRINTS PR00083 Histidinol dehydrogenase signature 160 186 8.1E-76 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 SMALA_RS07015 aa4d8d6a388a54ae676af143c08c272c 436 Gene3D G3DSA:3.40.50.1980 216 361 8.7E-61 T 29-03-2018 SMALA_RS07015 aa4d8d6a388a54ae676af143c08c272c 436 SUPERFAMILY SSF53720 16 409 6.67E-68 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMALA_RS07015 aa4d8d6a388a54ae676af143c08c272c 436 Gene3D G3DSA:3.40.50.1980 16 215 3.3E-72 T 29-03-2018 SMALA_RS07015 aa4d8d6a388a54ae676af143c08c272c 436 Pfam PF00815 Histidinol dehydrogenase 13 417 4.2E-136 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 SMALA_RS29240 3059f8c7bfb5600e6bb895f51d9e3949 159 Gene3D G3DSA:2.40.50.140 67 155 8.7E-8 T 29-03-2018 SMALA_RS29240 3059f8c7bfb5600e6bb895f51d9e3949 159 PIRSF PIRSF006910 5 156 2.2E-53 T 29-03-2018 IPR016499 Nucleic acid binding protein, Rv2694c, predicted SMALA_RS09715 e268043bdbd7754a74f3e1740d1bed73 122 Gene3D G3DSA:1.25.40.10 13 81 5.4E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS09715 e268043bdbd7754a74f3e1740d1bed73 122 SMART SM00028 77 110 2.8 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS09715 e268043bdbd7754a74f3e1740d1bed73 122 SMART SM00028 43 76 38.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS09715 e268043bdbd7754a74f3e1740d1bed73 122 Gene3D G3DSA:1.20.58.280 82 117 5.4E-4 T 29-03-2018 SMALA_RS09715 e268043bdbd7754a74f3e1740d1bed73 122 SUPERFAMILY SSF48452 6 109 7.05E-17 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS09715 e268043bdbd7754a74f3e1740d1bed73 122 Pfam PF14559 Tetratricopeptide repeat 19 77 2.3E-7 T 29-03-2018 SMALA_RS39825 eddd8186dc7f7cfa82d98c54b4694162 293 SUPERFAMILY SSF53720 13 261 2.09E-42 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMALA_RS39825 eddd8186dc7f7cfa82d98c54b4694162 293 Pfam PF00171 Aldehyde dehydrogenase family 37 260 3.2E-38 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS39825 eddd8186dc7f7cfa82d98c54b4694162 293 Gene3D G3DSA:3.40.605.10 14 262 2.3E-54 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS42430 1721a522c1dcb45243bc629f26fc38f4 245 SUPERFAMILY SSF56112 6 207 1.14E-18 T 29-03-2018 IPR011009 Protein kinase-like domain SMALA_RS42430 1721a522c1dcb45243bc629f26fc38f4 245 Gene3D G3DSA:1.10.510.10 22 184 2.4E-14 T 29-03-2018 SMALA_RS42430 1721a522c1dcb45243bc629f26fc38f4 245 Pfam PF01636 Phosphotransferase enzyme family 87 155 1.3E-9 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase SMALA_RS39430 9737a36a196c453b46ed07d0c40bbc51 226 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 6 15 - T 29-03-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 SMALA_RS39430 9737a36a196c453b46ed07d0c40bbc51 226 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 181 5.9E-37 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SMALA_RS39430 9737a36a196c453b46ed07d0c40bbc51 226 SUPERFAMILY SSF53254 1 195 3.4E-56 T 29-03-2018 IPR029033 Histidine phosphatase superfamily SMALA_RS39430 9737a36a196c453b46ed07d0c40bbc51 226 SMART SM00855 3 164 1.7E-21 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SMALA_RS39430 9737a36a196c453b46ed07d0c40bbc51 226 TIGRFAM TIGR01258 pgm_1: phosphoglycerate mutase 1 family 3 122 3.5E-33 T 29-03-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 SMALA_RS39430 9737a36a196c453b46ed07d0c40bbc51 226 Gene3D G3DSA:3.40.50.1240 1 213 1.5E-52 T 29-03-2018 IPR029033 Histidine phosphatase superfamily SMALA_RS39430 9737a36a196c453b46ed07d0c40bbc51 226 Hamap MF_01039 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [gpmA]. 1 205 31.997 T 29-03-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 SMALA_RS39430 9737a36a196c453b46ed07d0c40bbc51 226 PIRSF PIRSF000709 2 194 1.1E-9 T 29-03-2018 SMALA_RS02105 01f3c1fd6aa3e84d7e7844c746bb2f94 204 Pfam PF03358 NADPH-dependent FMN reductase 12 157 6.9E-35 T 29-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 SMALA_RS02105 01f3c1fd6aa3e84d7e7844c746bb2f94 204 Gene3D G3DSA:3.40.50.360 2 204 2.2E-38 T 29-03-2018 IPR029039 Flavoprotein-like domain SMALA_RS02105 01f3c1fd6aa3e84d7e7844c746bb2f94 204 SUPERFAMILY SSF52218 12 180 1.12E-36 T 29-03-2018 IPR029039 Flavoprotein-like domain SMALA_RS39715 83df4b58c121aaed08d90e10c9c83a3c 405 Pfam PF00067 Cytochrome P450 185 374 4.1E-23 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS39715 83df4b58c121aaed08d90e10c9c83a3c 405 SUPERFAMILY SSF48264 15 405 2.49E-86 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS39715 83df4b58c121aaed08d90e10c9c83a3c 405 Gene3D G3DSA:1.10.630.10 7 405 1.0E-73 T 29-03-2018 SMALA_RS39715 83df4b58c121aaed08d90e10c9c83a3c 405 PRINTS PR00359 B-class P450 signature 296 323 7.2E-46 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS39715 83df4b58c121aaed08d90e10c9c83a3c 405 PRINTS PR00359 B-class P450 signature 196 218 7.2E-46 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS39715 83df4b58c121aaed08d90e10c9c83a3c 405 PRINTS PR00359 B-class P450 signature 354 365 7.2E-46 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS39715 83df4b58c121aaed08d90e10c9c83a3c 405 PRINTS PR00359 B-class P450 signature 158 173 7.2E-46 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS39715 83df4b58c121aaed08d90e10c9c83a3c 405 PRINTS PR00359 B-class P450 signature 345 354 7.2E-46 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS39715 83df4b58c121aaed08d90e10c9c83a3c 405 PRINTS PR00359 B-class P450 signature 141 157 7.2E-46 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS39715 83df4b58c121aaed08d90e10c9c83a3c 405 PRINTS PR00359 B-class P450 signature 324 339 7.2E-46 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS39715 83df4b58c121aaed08d90e10c9c83a3c 405 PRINTS PR00359 B-class P450 signature 278 289 7.2E-46 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS39715 83df4b58c121aaed08d90e10c9c83a3c 405 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 347 356 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMALA_RS39715 83df4b58c121aaed08d90e10c9c83a3c 405 PRINTS PR00385 P450 superfamily signature 345 354 7.3E-6 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS39715 83df4b58c121aaed08d90e10c9c83a3c 405 PRINTS PR00385 P450 superfamily signature 354 365 7.3E-6 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS39715 83df4b58c121aaed08d90e10c9c83a3c 405 PRINTS PR00385 P450 superfamily signature 243 260 7.3E-6 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS03870 5a50e8d7417fa9d4758b0f21a48ff31e 325 Gene3D G3DSA:3.40.50.620 148 325 5.3E-22 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS03870 5a50e8d7417fa9d4758b0f21a48ff31e 325 PRINTS PR01438 Universal stress protein signature 5 23 5.2E-13 T 29-03-2018 IPR006015 Universal stress protein A SMALA_RS03870 5a50e8d7417fa9d4758b0f21a48ff31e 325 PRINTS PR01438 Universal stress protein signature 102 114 5.2E-13 T 29-03-2018 IPR006015 Universal stress protein A SMALA_RS03870 5a50e8d7417fa9d4758b0f21a48ff31e 325 PRINTS PR01438 Universal stress protein signature 120 142 5.2E-13 T 29-03-2018 IPR006015 Universal stress protein A SMALA_RS03870 5a50e8d7417fa9d4758b0f21a48ff31e 325 Pfam PF00582 Universal stress protein family 175 323 4.2E-12 T 29-03-2018 IPR006016 UspA GO:0006950 SMALA_RS03870 5a50e8d7417fa9d4758b0f21a48ff31e 325 Pfam PF00582 Universal stress protein family 8 142 2.4E-22 T 29-03-2018 IPR006016 UspA GO:0006950 SMALA_RS03870 5a50e8d7417fa9d4758b0f21a48ff31e 325 SUPERFAMILY SSF52402 242 323 1.67E-17 T 29-03-2018 SMALA_RS03870 5a50e8d7417fa9d4758b0f21a48ff31e 325 SUPERFAMILY SSF52402 171 211 1.67E-17 T 29-03-2018 SMALA_RS03870 5a50e8d7417fa9d4758b0f21a48ff31e 325 SUPERFAMILY SSF52402 8 145 4.81E-25 T 29-03-2018 SMALA_RS03870 5a50e8d7417fa9d4758b0f21a48ff31e 325 Gene3D G3DSA:3.40.50.620 5 147 1.7E-27 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS10765 eac7a5954de9714c5bf7900e08c058a5 610 SUPERFAMILY SSF90123 23 323 2.22E-16 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMALA_RS10765 eac7a5954de9714c5bf7900e08c058a5 610 Gene3D G3DSA:1.20.1560.10 19 340 1.5E-16 T 29-03-2018 SMALA_RS10765 eac7a5954de9714c5bf7900e08c058a5 610 Gene3D G3DSA:3.40.50.300 344 602 7.8E-64 T 29-03-2018 SMALA_RS10765 eac7a5954de9714c5bf7900e08c058a5 610 SMART SM00382 384 573 7.5E-20 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS10765 eac7a5954de9714c5bf7900e08c058a5 610 Pfam PF00005 ABC transporter 375 527 1.7E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS10765 eac7a5954de9714c5bf7900e08c058a5 610 SUPERFAMILY SSF52540 354 597 2.19E-69 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS10765 eac7a5954de9714c5bf7900e08c058a5 610 ProSitePatterns PS00211 ABC transporters family signature. 499 513 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS32375 937785a5b29d33670cfe8b1b6c85ebaa 391 Pfam PF07690 Major Facilitator Superfamily 28 352 3.6E-13 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS32375 937785a5b29d33670cfe8b1b6c85ebaa 391 SUPERFAMILY SSF103473 20 389 3.14E-26 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS32375 937785a5b29d33670cfe8b1b6c85ebaa 391 Gene3D G3DSA:1.20.1250.20 3 192 3.8E-14 T 29-03-2018 SMALA_RS32375 937785a5b29d33670cfe8b1b6c85ebaa 391 Gene3D G3DSA:1.20.1250.20 208 391 2.6E-5 T 29-03-2018 SMALA_RS24710 0554dbb8d16564a13b02f39befe1375b 1062 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 1 207 3.2E-25 T 29-03-2018 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 SMALA_RS24710 0554dbb8d16564a13b02f39befe1375b 1062 Gene3D G3DSA:3.40.50.300 32 472 1.0E-22 T 29-03-2018 SMALA_RS24710 0554dbb8d16564a13b02f39befe1375b 1062 Pfam PF11867 Domain of unknown function (DUF3387) 721 1059 4.4E-105 T 29-03-2018 IPR021810 Protein of unknown function DUF3387 SMALA_RS24710 0554dbb8d16564a13b02f39befe1375b 1062 Pfam PF04851 Type III restriction enzyme, res subunit 273 450 6.2E-16 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 SMALA_RS24710 0554dbb8d16564a13b02f39befe1375b 1062 SUPERFAMILY SSF52540 228 488 4.43E-24 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS24710 0554dbb8d16564a13b02f39befe1375b 1062 SMART SM00487 266 483 4.6E-11 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain SMALA_RS24710 0554dbb8d16564a13b02f39befe1375b 1062 TIGRFAM TIGR00348 hsdR: type I site-specific deoxyribonuclease, HsdR family 12 720 2.9E-131 T 29-03-2018 IPR004473 Restriction endonuclease, type I, HsdR GO:0003677|GO:0005524|GO:0009035|GO:0009307 SMALA_RS00775 602e8cddcc03ac80ace74ae66c4d5b7b 243 Gene3D G3DSA:3.20.20.370 42 239 9.4E-40 T 29-03-2018 SMALA_RS00775 602e8cddcc03ac80ace74ae66c4d5b7b 243 Pfam PF01522 Polysaccharide deacetylase 47 164 2.4E-25 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 SMALA_RS00775 602e8cddcc03ac80ace74ae66c4d5b7b 243 SUPERFAMILY SSF88713 48 238 1.48E-47 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 SMALA_RS08915 b65026e3ea79eee34c0a6b5b529d51c1 474 Gene3D G3DSA:1.20.1250.20 31 226 1.6E-22 T 29-03-2018 SMALA_RS08915 b65026e3ea79eee34c0a6b5b529d51c1 474 SUPERFAMILY SSF103473 272 466 3.01E-47 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS08915 b65026e3ea79eee34c0a6b5b529d51c1 474 SUPERFAMILY SSF103473 28 226 3.01E-47 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS08915 b65026e3ea79eee34c0a6b5b529d51c1 474 TIGRFAM TIGR00896 CynX: cyanate transporter 43 446 1.2E-125 T 29-03-2018 IPR004747 Cyanate transport system protein GO:0016021 SMALA_RS08915 b65026e3ea79eee34c0a6b5b529d51c1 474 Gene3D G3DSA:1.20.1250.20 279 469 2.4E-17 T 29-03-2018 SMALA_RS08915 b65026e3ea79eee34c0a6b5b529d51c1 474 Pfam PF07690 Major Facilitator Superfamily 56 425 1.9E-24 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS38235 d3c4b7285b12a46c2f9b76570dd17ed1 90 Gene3D G3DSA:1.10.1200.10 1 90 1.6E-16 T 29-03-2018 SMALA_RS38235 d3c4b7285b12a46c2f9b76570dd17ed1 90 SMART SM00823 Phosphopantetheine attachment site 15 86 6.8E-13 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS38235 d3c4b7285b12a46c2f9b76570dd17ed1 90 SUPERFAMILY SSF47336 10 87 6.94E-18 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS38235 d3c4b7285b12a46c2f9b76570dd17ed1 90 Pfam PF00550 Phosphopantetheine attachment site 16 82 1.0E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS17455 115cf8bceeedd1083b25a6ed80d0c91f 412 Pfam PF07690 Major Facilitator Superfamily 9 333 1.7E-39 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS17455 115cf8bceeedd1083b25a6ed80d0c91f 412 PRINTS PR01035 Tetracycline resistance protein signature 40 59 5.3E-5 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 SMALA_RS17455 115cf8bceeedd1083b25a6ed80d0c91f 412 PRINTS PR01035 Tetracycline resistance protein signature 133 155 5.3E-5 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 SMALA_RS17455 115cf8bceeedd1083b25a6ed80d0c91f 412 PRINTS PR01035 Tetracycline resistance protein signature 10 26 5.3E-5 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 SMALA_RS17455 115cf8bceeedd1083b25a6ed80d0c91f 412 PRINTS PR01035 Tetracycline resistance protein signature 257 277 5.3E-5 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 SMALA_RS17455 115cf8bceeedd1083b25a6ed80d0c91f 412 Gene3D G3DSA:1.20.1250.20 4 194 7.8E-27 T 29-03-2018 SMALA_RS17455 115cf8bceeedd1083b25a6ed80d0c91f 412 Gene3D G3DSA:1.20.1250.20 196 385 3.3E-18 T 29-03-2018 SMALA_RS17455 115cf8bceeedd1083b25a6ed80d0c91f 412 SUPERFAMILY SSF103473 3 379 2.62E-56 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS17315 850352017dd5cb306a218f437b3fef62 153 SUPERFAMILY SSF46785 18 144 5.18E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS17315 850352017dd5cb306a218f437b3fef62 153 SMART SM00347 37 137 1.0E-22 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS17315 850352017dd5cb306a218f437b3fef62 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 61 77 5.5E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS17315 850352017dd5cb306a218f437b3fef62 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 78 93 5.5E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS17315 850352017dd5cb306a218f437b3fef62 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 97 113 5.5E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS17315 850352017dd5cb306a218f437b3fef62 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 127 147 5.5E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS17315 850352017dd5cb306a218f437b3fef62 153 Pfam PF12802 MarR family 44 101 3.8E-14 T 29-03-2018 SMALA_RS17315 850352017dd5cb306a218f437b3fef62 153 Gene3D G3DSA:1.10.10.10 15 121 4.4E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS17315 850352017dd5cb306a218f437b3fef62 153 ProSitePatterns PS01117 MarR-type HTH domain signature. 76 110 - T 29-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site SMALA_RS17315 850352017dd5cb306a218f437b3fef62 153 Gene3D G3DSA:1.10.287.100 122 152 4.4E-14 T 29-03-2018 SMALA_RS05885 bfc86774457a49fb13414b12af712da8 282 Pfam PF13460 NAD(P)H-binding 7 183 7.6E-23 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS05885 bfc86774457a49fb13414b12af712da8 282 Gene3D G3DSA:3.40.50.720 1 72 2.0E-12 T 29-03-2018 SMALA_RS05885 bfc86774457a49fb13414b12af712da8 282 Gene3D G3DSA:3.40.50.720 79 271 5.2E-14 T 29-03-2018 SMALA_RS05885 bfc86774457a49fb13414b12af712da8 282 SUPERFAMILY SSF51735 4 242 5.18E-44 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS30285 928100f881717cc8bdc03c3b28c15fc5 177 Pfam PF00583 Acetyltransferase (GNAT) family 54 166 4.5E-7 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SMALA_RS30285 928100f881717cc8bdc03c3b28c15fc5 177 Gene3D G3DSA:3.40.630.30 17 174 2.7E-19 T 29-03-2018 SMALA_RS30285 928100f881717cc8bdc03c3b28c15fc5 177 SUPERFAMILY SSF55729 51 171 1.01E-17 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS31280 f27928e6fdecd06ada26f0a4e0f79115 443 Pfam PF00144 Beta-lactamase 78 425 7.3E-56 T 29-03-2018 IPR001466 Beta-lactamase-related SMALA_RS31280 f27928e6fdecd06ada26f0a4e0f79115 443 SUPERFAMILY SSF56601 76 419 3.38E-70 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMALA_RS31280 f27928e6fdecd06ada26f0a4e0f79115 443 Gene3D G3DSA:3.40.710.10 72 434 1.0E-69 T 29-03-2018 SMALA_RS11990 bb2f92641ce9751f87f6362633ae957f 151 Gene3D G3DSA:1.10.287.100 94 123 1.4E-4 T 29-03-2018 SMALA_RS11990 bb2f92641ce9751f87f6362633ae957f 151 Pfam PF12802 MarR family 23 75 2.6E-12 T 29-03-2018 SMALA_RS11990 bb2f92641ce9751f87f6362633ae957f 151 Gene3D G3DSA:1.10.10.10 2 93 2.1E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS11990 bb2f92641ce9751f87f6362633ae957f 151 ProSitePatterns PS01117 MarR-type HTH domain signature. 50 84 - T 29-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site SMALA_RS11990 bb2f92641ce9751f87f6362633ae957f 151 SUPERFAMILY SSF46785 12 128 2.86E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS11990 bb2f92641ce9751f87f6362633ae957f 151 SMART SM00347 11 111 2.5E-14 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS16220 72fcbb2b69681654a8e3292b4f6085e8 332 SUPERFAMILY SSF53955 41 122 5.62E-27 T 29-03-2018 IPR023346 Lysozyme-like domain SMALA_RS16220 72fcbb2b69681654a8e3292b4f6085e8 332 Gene3D G3DSA:3.10.350.10 277 327 1.2E-10 T 29-03-2018 SMALA_RS16220 72fcbb2b69681654a8e3292b4f6085e8 332 Gene3D G3DSA:1.10.530.10 18 123 1.4E-26 T 29-03-2018 SMALA_RS16220 72fcbb2b69681654a8e3292b4f6085e8 332 Pfam PF06737 Transglycosylase-like domain 41 116 1.3E-31 T 29-03-2018 IPR010618 Transglycosylase-like SMALA_RS41975 fb24b2f06992ef01346f449d102313d8 332 Gene3D G3DSA:3.40.50.300 30 196 4.2E-25 T 29-03-2018 SMALA_RS41975 fb24b2f06992ef01346f449d102313d8 332 PIRSF PIRSF002849 2 324 6.8E-126 T 29-03-2018 SMALA_RS41975 fb24b2f06992ef01346f449d102313d8 332 Gene3D G3DSA:1.10.8.300 211 319 3.6E-31 T 29-03-2018 SMALA_RS41975 fb24b2f06992ef01346f449d102313d8 332 SUPERFAMILY SSF52540 27 300 3.44E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS41975 fb24b2f06992ef01346f449d102313d8 332 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 49 178 2.5E-62 T 29-03-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 SMALA_RS29155 a3606fcfe20fd4de7c8754899b45f86b 355 Gene3D G3DSA:1.10.260.40 33 216 7.7E-4 T 29-03-2018 SMALA_RS29155 a3606fcfe20fd4de7c8754899b45f86b 355 Pfam PF11268 Protein of unknown function (DUF3071) 12 179 5.7E-55 T 29-03-2018 IPR021421 Protein of unknown function DUF3071 SMALA_RS13450 a6efb61eeb84f5db85955d56498994e7 365 Gene3D G3DSA:3.30.420.40 24 154 2.0E-15 T 29-03-2018 SMALA_RS13450 a6efb61eeb84f5db85955d56498994e7 365 Gene3D G3DSA:3.30.420.40 155 309 1.8E-33 T 29-03-2018 SMALA_RS13450 a6efb61eeb84f5db85955d56498994e7 365 SUPERFAMILY SSF53067 145 336 8.46E-34 T 29-03-2018 SMALA_RS13450 a6efb61eeb84f5db85955d56498994e7 365 SUPERFAMILY SSF53067 29 137 2.04E-15 T 29-03-2018 SMALA_RS13450 a6efb61eeb84f5db85955d56498994e7 365 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 32 331 2.9E-14 T 29-03-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 SMALA_RS37635 3f35a2cb80b65262e8365db85a91e023 134 SMART SM00960 8 98 3.9E-28 T 29-03-2018 IPR004942 Roadblock/LAMTOR2 domain SMALA_RS37635 3f35a2cb80b65262e8365db85a91e023 134 SUPERFAMILY SSF103196 6 127 5.76E-34 T 29-03-2018 SMALA_RS37635 3f35a2cb80b65262e8365db85a91e023 134 Gene3D G3DSA:3.30.450.30 3 130 3.3E-43 T 29-03-2018 SMALA_RS37635 3f35a2cb80b65262e8365db85a91e023 134 Pfam PF03259 Roadblock/LC7 domain 7 98 1.4E-26 T 29-03-2018 IPR004942 Roadblock/LAMTOR2 domain SMALA_RS19415 2aea375786f04813785591e05eab6758 333 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 3 320 4.6E-118 T 29-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 SMALA_RS19415 2aea375786f04813785591e05eab6758 333 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 2 214 1.6E-74 T 29-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 SMALA_RS19415 2aea375786f04813785591e05eab6758 333 PIRSF PIRSF000267 1 333 3.7E-124 T 29-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 SMALA_RS06205 f0713e483d170a6934e0fe8c3205ef4c 256 SUPERFAMILY SSF160104 17 163 1.22E-14 T 29-03-2018 IPR023375 Acetoacetate decarboxylase beta barrel domain KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 SMALA_RS06205 f0713e483d170a6934e0fe8c3205ef4c 256 Pfam PF09844 Uncharacterized conserved protein (COG2071) 25 238 7.6E-69 T 29-03-2018 IPR018644 Protein of unknown function DUF2071 SMALA_RS06205 f0713e483d170a6934e0fe8c3205ef4c 256 Gene3D G3DSA:2.40.400.10 4 240 4.0E-37 T 29-03-2018 IPR023375 Acetoacetate decarboxylase beta barrel domain KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 SMALA_RS02025 27a9b2cbf9630dd5e21b2a5bab3d7f8e 838 Pfam PF02687 FtsX-like permease family 741 828 1.8E-8 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 SMALA_RS02025 27a9b2cbf9630dd5e21b2a5bab3d7f8e 838 Pfam PF02687 FtsX-like permease family 290 382 3.1E-13 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 SMALA_RS02025 27a9b2cbf9630dd5e21b2a5bab3d7f8e 838 Pfam PF12704 MacB-like periplasmic core domain 20 231 2.5E-13 T 29-03-2018 IPR025857 MacB-like periplasmic core domain SMALA_RS07970 64314d26a49d1d0b4f0b3803a43c9090 241 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 115 137 - T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 SMALA_RS07970 64314d26a49d1d0b4f0b3803a43c9090 241 Pfam PF01066 CDP-alcohol phosphatidyltransferase 69 137 1.3E-9 T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 SMALA_RS04750 e2bfe4d3ae1b4b483f760be75956ae0a 283 Gene3D G3DSA:3.40.50.150 7 281 2.3E-44 T 29-03-2018 SMALA_RS04750 e2bfe4d3ae1b4b483f760be75956ae0a 283 PIRSF PIRSF018249 1 282 5.5E-90 T 29-03-2018 IPR016718 rRNA (guanine-N1-)-methyltransferase A, predicted GO:0008168 SMALA_RS04750 e2bfe4d3ae1b4b483f760be75956ae0a 283 SUPERFAMILY SSF53335 11 213 2.46E-30 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS04750 e2bfe4d3ae1b4b483f760be75956ae0a 283 Pfam PF00891 O-methyltransferase 96 155 1.9E-5 T 29-03-2018 IPR001077 O-methyltransferase, family 2 GO:0008171 SMALA_RS34325 5b75210504e573dffd4bb22648b33f11 321 Gene3D G3DSA:1.20.58.370 21 69 5.9E-6 T 29-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain SMALA_RS34325 5b75210504e573dffd4bb22648b33f11 321 Gene3D G3DSA:1.10.3720.10 84 315 2.0E-44 T 29-03-2018 SMALA_RS34325 5b75210504e573dffd4bb22648b33f11 321 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 125 306 2.8E-16 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS34325 5b75210504e573dffd4bb22648b33f11 321 SUPERFAMILY SSF161098 79 306 2.22E-59 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS12165 0f5328020785659982350ba9eb776743 258 Gene3D G3DSA:1.10.10.10 2 67 2.4E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS12165 0f5328020785659982350ba9eb776743 258 Gene3D G3DSA:3.30.450.40 74 257 4.0E-51 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS12165 0f5328020785659982350ba9eb776743 258 Pfam PF09339 IclR helix-turn-helix domain 7 58 3.7E-14 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMALA_RS12165 0f5328020785659982350ba9eb776743 258 SMART SM00346 5 96 1.5E-15 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMALA_RS12165 0f5328020785659982350ba9eb776743 258 SUPERFAMILY SSF46785 5 80 3.96E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS12165 0f5328020785659982350ba9eb776743 258 Pfam PF01614 Bacterial transcriptional regulator 124 248 6.3E-34 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal SMALA_RS12165 0f5328020785659982350ba9eb776743 258 SUPERFAMILY SSF55781 71 253 3.92E-51 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS18120 b9fb449aaad017b3a40e220f8871d420 179 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 8 172 5.8E-66 T 29-03-2018 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620 SMALA_RS18120 b9fb449aaad017b3a40e220f8871d420 179 SUPERFAMILY SSF53271 4 177 4.2E-55 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like SMALA_RS18120 b9fb449aaad017b3a40e220f8871d420 179 Pfam PF00156 Phosphoribosyl transferase domain 14 159 1.2E-24 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 SMALA_RS18120 b9fb449aaad017b3a40e220f8871d420 179 Gene3D G3DSA:3.40.50.2020 1 178 1.4E-43 T 29-03-2018 SMALA_RS21390 537020be3c26b2676ff3352b3170e51b 137 Pfam PF01381 Helix-turn-helix 13 65 3.5E-15 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS21390 537020be3c26b2676ff3352b3170e51b 137 Gene3D G3DSA:1.10.260.40 3 119 1.8E-19 T 29-03-2018 SMALA_RS21390 537020be3c26b2676ff3352b3170e51b 137 SUPERFAMILY SSF47413 8 69 6.97E-17 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS21390 537020be3c26b2676ff3352b3170e51b 137 SMART SM00530 12 67 6.4E-16 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS29725 51b6677d93d08a148a69d6c3f0874b36 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 59 6.3E-17 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS29725 51b6677d93d08a148a69d6c3f0874b36 299 Gene3D G3DSA:1.10.10.10 1 81 1.3E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS29725 51b6677d93d08a148a69d6c3f0874b36 299 SUPERFAMILY SSF53850 90 280 3.5E-20 T 29-03-2018 SMALA_RS29725 51b6677d93d08a148a69d6c3f0874b36 299 Gene3D G3DSA:3.40.190.10 184 272 1.5E-16 T 29-03-2018 SMALA_RS29725 51b6677d93d08a148a69d6c3f0874b36 299 Pfam PF03466 LysR substrate binding domain 88 269 4.2E-19 T 29-03-2018 IPR005119 LysR, substrate-binding SMALA_RS29725 51b6677d93d08a148a69d6c3f0874b36 299 Gene3D G3DSA:3.40.190.10 86 183 3.4E-15 T 29-03-2018 SMALA_RS29725 51b6677d93d08a148a69d6c3f0874b36 299 SUPERFAMILY SSF46785 1 108 4.49E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS07240 c1ef7454ee2ab5e4bde758a13b4202af 326 Gene3D G3DSA:1.10.260.40 1 50 1.7E-19 T 29-03-2018 SMALA_RS07240 c1ef7454ee2ab5e4bde758a13b4202af 326 SUPERFAMILY SSF47413 1 55 6.66E-13 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS07240 c1ef7454ee2ab5e4bde758a13b4202af 326 Pfam PF00356 Bacterial regulatory proteins, lacI family 1 44 4.8E-13 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS07240 c1ef7454ee2ab5e4bde758a13b4202af 326 SMART SM00354 1 67 9.0E-20 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS07240 c1ef7454ee2ab5e4bde758a13b4202af 326 Gene3D G3DSA:3.40.50.2300 169 323 6.5E-39 T 29-03-2018 SMALA_RS07240 c1ef7454ee2ab5e4bde758a13b4202af 326 Gene3D G3DSA:3.40.50.2300 51 168 1.9E-28 T 29-03-2018 SMALA_RS07240 c1ef7454ee2ab5e4bde758a13b4202af 326 SUPERFAMILY SSF53822 54 314 1.65E-52 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SMALA_RS07240 c1ef7454ee2ab5e4bde758a13b4202af 326 Pfam PF13377 Periplasmic binding protein-like domain 163 320 1.2E-34 T 29-03-2018 SMALA_RS01155 b8d436b60829f0ff483e2d5414900298 346 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 206 215 - T 29-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 SMALA_RS01155 b8d436b60829f0ff483e2d5414900298 346 Pfam PF00155 Aminotransferase class I and II 27 326 3.4E-41 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMALA_RS01155 b8d436b60829f0ff483e2d5414900298 346 Gene3D G3DSA:3.90.1150.10 237 342 8.7E-17 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS01155 b8d436b60829f0ff483e2d5414900298 346 SUPERFAMILY SSF53383 12 334 3.24E-67 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS01155 b8d436b60829f0ff483e2d5414900298 346 Gene3D G3DSA:3.40.640.10 31 236 2.0E-33 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS33770 ba40aae6148cf8d2017f3b1df2cc4ffb 285 SUPERFAMILY SSF49899 40 281 7.33E-72 T 29-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain SMALA_RS33770 ba40aae6148cf8d2017f3b1df2cc4ffb 285 Gene3D G3DSA:2.60.120.200 34 281 5.6E-73 T 29-03-2018 SMALA_RS33770 ba40aae6148cf8d2017f3b1df2cc4ffb 285 Pfam PF00722 Glycosyl hydrolases family 16 72 279 7.5E-42 T 29-03-2018 IPR000757 Glycoside hydrolase family 16 GO:0004553|GO:0005975 SMALA_RS24705 ea777a8a97db3479015bd4fdf4134734 414 SUPERFAMILY SSF116734 12 196 3.6E-27 T 29-03-2018 SMALA_RS24705 ea777a8a97db3479015bd4fdf4134734 414 Gene3D G3DSA:3.90.220.20 7 191 4.7E-21 T 29-03-2018 SMALA_RS24705 ea777a8a97db3479015bd4fdf4134734 414 SUPERFAMILY SSF116734 210 407 7.19E-20 T 29-03-2018 SMALA_RS24705 ea777a8a97db3479015bd4fdf4134734 414 Gene3D G3DSA:3.90.220.20 192 359 5.4E-12 T 29-03-2018 SMALA_RS24705 ea777a8a97db3479015bd4fdf4134734 414 Pfam PF01420 Type I restriction modification DNA specificity domain 16 191 1.8E-7 T 29-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 SMALA_RS36275 7cf2b71a503c75f091de92fb06a1f9c5 303 Gene3D G3DSA:3.40.50.10490 1 162 8.2E-25 T 29-03-2018 SMALA_RS36275 7cf2b71a503c75f091de92fb06a1f9c5 303 Gene3D G3DSA:3.40.50.10490 167 293 3.4E-24 T 29-03-2018 SMALA_RS36275 7cf2b71a503c75f091de92fb06a1f9c5 303 SUPERFAMILY SSF53697 5 294 1.48E-43 T 29-03-2018 SMALA_RS36275 7cf2b71a503c75f091de92fb06a1f9c5 303 Pfam PF01380 SIS domain 38 149 6.2E-6 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 SMALA_RS11155 77fa3feb9d3e5c98e80b35f9fac6825b 265 SUPERFAMILY SSF53335 78 203 2.13E-28 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS11155 77fa3feb9d3e5c98e80b35f9fac6825b 265 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 73 193 8.3E-28 T 29-03-2018 SMALA_RS11155 77fa3feb9d3e5c98e80b35f9fac6825b 265 Gene3D G3DSA:3.40.50.150 1 241 1.3E-35 T 29-03-2018 SMALA_RS03805 f7a64e32220194b9bf706c9cd5a8c52e 475 SUPERFAMILY SSF103473 5 448 2.49E-64 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS03805 f7a64e32220194b9bf706c9cd5a8c52e 475 Pfam PF00083 Sugar (and other) transporter 24 449 3.0E-33 T 29-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 SMALA_RS03805 f7a64e32220194b9bf706c9cd5a8c52e 475 Gene3D G3DSA:1.20.1250.20 239 456 1.4E-23 T 29-03-2018 SMALA_RS03805 f7a64e32220194b9bf706c9cd5a8c52e 475 Gene3D G3DSA:1.20.1250.20 18 234 4.2E-24 T 29-03-2018 SMALA_RS03805 f7a64e32220194b9bf706c9cd5a8c52e 475 ProSitePatterns PS00217 Sugar transport proteins signature 2. 132 157 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMALA_RS19585 10d8aa006d33b5eb2d81883580c0e12c 96 Pfam PF01250 Ribosomal protein S6 3 92 2.0E-28 T 29-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS19585 10d8aa006d33b5eb2d81883580c0e12c 96 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 95 22.132 T 29-03-2018 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 SMALA_RS19585 10d8aa006d33b5eb2d81883580c0e12c 96 Gene3D G3DSA:3.30.70.60 1 96 2.0E-28 T 29-03-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 SMALA_RS19585 10d8aa006d33b5eb2d81883580c0e12c 96 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 92 9.4E-26 T 29-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS19585 10d8aa006d33b5eb2d81883580c0e12c 96 SUPERFAMILY SSF54995 1 94 5.49E-32 T 29-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS19585 10d8aa006d33b5eb2d81883580c0e12c 96 ProSitePatterns PS01048 Ribosomal protein S6 signature. 44 53 - T 29-03-2018 IPR020815 Ribosomal protein S6, conserved site GO:0003735|GO:0005840|GO:0006412|GO:0019843 SMALA_RS39990 bb21ba1e23581bb8d0da13e6949325f4 558 ProDom PD018364 ISOMERASE L-ARABINOSE ARABINOSE METABOLISM CARBOHYDRATE CATABOLISM ARAA 94 388 6.0E-11 T 29-03-2018 IPR003762 L-arabinose isomerase GO:0008152|GO:0008733 KEGG: 00040+5.3.1.4 SMALA_RS39990 bb21ba1e23581bb8d0da13e6949325f4 558 SUPERFAMILY SSF50443 413 557 2.88E-23 T 29-03-2018 IPR004216 L-fucose/L-arabinose isomerase, C-terminal SMALA_RS39990 bb21ba1e23581bb8d0da13e6949325f4 558 Pfam PF02610 L-arabinose isomerase 113 425 8.0E-17 T 29-03-2018 IPR003762 L-arabinose isomerase GO:0008152|GO:0008733 KEGG: 00040+5.3.1.4 SMALA_RS39990 bb21ba1e23581bb8d0da13e6949325f4 558 Gene3D G3DSA:3.40.50.1070 109 264 7.2E-12 T 29-03-2018 SMALA_RS39990 bb21ba1e23581bb8d0da13e6949325f4 558 SUPERFAMILY SSF53743 93 416 2.22E-73 T 29-03-2018 IPR009015 L-fucose isomerase, N-terminal/central domain GO:0005737|GO:0005996|GO:0016861 SMALA_RS12815 7e399ab8a3d1766a173967e20338a53e 142 SUPERFAMILY SSF50475 7 138 9.54E-21 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS12815 7e399ab8a3d1766a173967e20338a53e 142 Gene3D G3DSA:2.30.110.10 1 141 4.7E-20 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS12815 7e399ab8a3d1766a173967e20338a53e 142 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 8 91 6.1E-10 T 29-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 SMALA_RS41255 3a2c3a5cb1591fb839f26557a0ed1a55 357 Pfam PF00248 Aldo/keto reductase family 18 313 1.2E-66 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS41255 3a2c3a5cb1591fb839f26557a0ed1a55 357 Gene3D G3DSA:3.20.20.100 5 319 2.5E-88 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS41255 3a2c3a5cb1591fb839f26557a0ed1a55 357 SUPERFAMILY SSF51430 6 315 1.05E-90 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS25410 bd1e3ced5f01be3ff2e98bdaaa7160e8 226 SMART SM00862 96 168 8.3E-22 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS25410 bd1e3ced5f01be3ff2e98bdaaa7160e8 226 Pfam PF00486 Transcriptional regulatory protein, C terminal 98 168 2.7E-19 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS25410 bd1e3ced5f01be3ff2e98bdaaa7160e8 226 Gene3D G3DSA:1.10.10.10 62 175 2.7E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS25410 bd1e3ced5f01be3ff2e98bdaaa7160e8 226 SUPERFAMILY SSF46894 74 169 2.41E-22 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS31200 bfb8f7949a985ef32ef2fbdc98d96479 123 Gene3D G3DSA:3.10.450.50 1 120 5.0E-21 T 29-03-2018 SMALA_RS31200 bfb8f7949a985ef32ef2fbdc98d96479 123 SUPERFAMILY SSF54427 1 117 5.46E-33 T 29-03-2018 IPR032710 NTF2-like domain SMALA_RS31200 bfb8f7949a985ef32ef2fbdc98d96479 123 Pfam PF12680 SnoaL-like domain 8 110 2.3E-14 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain SMALA_RS13180 506341f4c923d2b1044b91452b97fb41 137 PRINTS PR01243 Nucleoside diphosphate kinase signature 114 133 1.1E-42 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SMALA_RS13180 506341f4c923d2b1044b91452b97fb41 137 PRINTS PR01243 Nucleoside diphosphate kinase signature 5 27 1.1E-42 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SMALA_RS13180 506341f4c923d2b1044b91452b97fb41 137 PRINTS PR01243 Nucleoside diphosphate kinase signature 50 69 1.1E-42 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SMALA_RS13180 506341f4c923d2b1044b91452b97fb41 137 PRINTS PR01243 Nucleoside diphosphate kinase signature 91 107 1.1E-42 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SMALA_RS13180 506341f4c923d2b1044b91452b97fb41 137 PRINTS PR01243 Nucleoside diphosphate kinase signature 70 87 1.1E-42 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SMALA_RS13180 506341f4c923d2b1044b91452b97fb41 137 Pfam PF00334 Nucleoside diphosphate kinase 3 134 2.0E-51 T 29-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SMALA_RS13180 506341f4c923d2b1044b91452b97fb41 137 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 2 136 32.534 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SMALA_RS13180 506341f4c923d2b1044b91452b97fb41 137 SUPERFAMILY SSF54919 3 135 1.31E-52 T 29-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SMALA_RS13180 506341f4c923d2b1044b91452b97fb41 137 Gene3D G3DSA:3.30.70.141 56 135 8.3E-34 T 29-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SMALA_RS13180 506341f4c923d2b1044b91452b97fb41 137 Gene3D G3DSA:3.30.70.141 1 55 2.1E-15 T 29-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SMALA_RS13180 506341f4c923d2b1044b91452b97fb41 137 SMART SM00562 2 136 5.0E-73 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SMALA_RS29695 260dec39d72ceb5c454884a8a88d3d60 429 Gene3D G3DSA:3.40.190.10 153 428 5.6E-36 T 29-03-2018 SMALA_RS29695 260dec39d72ceb5c454884a8a88d3d60 429 Pfam PF01547 Bacterial extracellular solute-binding protein 56 344 1.1E-30 T 29-03-2018 IPR006059 Solute-binding family 1 GO:0006810 SMALA_RS29695 260dec39d72ceb5c454884a8a88d3d60 429 SUPERFAMILY SSF53850 34 427 2.85E-55 T 29-03-2018 SMALA_RS02530 d13538525614676bbeaca5f9cdb9f2b6 415 Gene3D G3DSA:1.20.1250.20 207 410 3.3E-17 T 29-03-2018 SMALA_RS02530 d13538525614676bbeaca5f9cdb9f2b6 415 SUPERFAMILY SSF103473 9 397 5.49E-37 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS02530 d13538525614676bbeaca5f9cdb9f2b6 415 Gene3D G3DSA:1.20.1250.20 4 199 5.5E-9 T 29-03-2018 SMALA_RS02530 d13538525614676bbeaca5f9cdb9f2b6 415 Pfam PF07690 Major Facilitator Superfamily 14 357 5.3E-22 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS37145 55d256fd43647a36c9454c7a036df79d 323 Gene3D G3DSA:3.30.70.20 20 151 4.0E-37 T 29-03-2018 SMALA_RS37145 55d256fd43647a36c9454c7a036df79d 323 SUPERFAMILY SSF54862 20 280 3.45E-58 T 29-03-2018 SMALA_RS37145 55d256fd43647a36c9454c7a036df79d 323 PIRSF PIRSF036298 11 322 2.6E-61 T 29-03-2018 IPR014603 Formate dehydrogenase iron-sulphur subunit GO:0015944|GO:0045333|GO:0051539 SMALA_RS37145 55d256fd43647a36c9454c7a036df79d 323 Pfam PF13247 4Fe-4S dicluster domain 129 223 4.4E-23 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain SMALA_RS37145 55d256fd43647a36c9454c7a036df79d 323 Gene3D G3DSA:3.30.70.20 189 298 1.6E-19 T 29-03-2018 SMALA_RS37145 55d256fd43647a36c9454c7a036df79d 323 Gene3D G3DSA:3.30.70.20 152 188 1.7E-18 T 29-03-2018 SMALA_RS37145 55d256fd43647a36c9454c7a036df79d 323 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 169 180 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site SMALA_RS18210 f29f446f4c39876c668a7eaf20f4eb64 383 SUPERFAMILY SSF54631 245 365 2.65E-9 T 29-03-2018 SMALA_RS18210 f29f446f4c39876c668a7eaf20f4eb64 383 Pfam PF02163 Peptidase family M50 129 195 2.5E-9 T 29-03-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889|Reactome: R-MMU-8963889 SMALA_RS18210 f29f446f4c39876c668a7eaf20f4eb64 383 PIRSF PIRSF006404 1 374 4.6E-80 T 29-03-2018 IPR016483 Uncharacterised conserved protein UCP006404, peptidase M50/CBS SMALA_RS18210 f29f446f4c39876c668a7eaf20f4eb64 383 Gene3D G3DSA:3.10.580.10 240 369 1.6E-11 T 29-03-2018 SMALA_RS10975 b554028100b377f13cbd1e1bbb0d8ce0 540 Gene3D G3DSA:1.20.1250.20 14 216 5.6E-35 T 29-03-2018 SMALA_RS10975 b554028100b377f13cbd1e1bbb0d8ce0 540 Gene3D G3DSA:1.20.1250.20 275 527 4.9E-30 T 29-03-2018 SMALA_RS10975 b554028100b377f13cbd1e1bbb0d8ce0 540 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 26 437 1.2E-78 T 29-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 SMALA_RS10975 b554028100b377f13cbd1e1bbb0d8ce0 540 Pfam PF07690 Major Facilitator Superfamily 30 426 6.3E-55 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS10975 b554028100b377f13cbd1e1bbb0d8ce0 540 PRINTS PR01036 Tetracycline resistance protein TetB signature 124 144 3.8E-7 T 29-03-2018 SMALA_RS10975 b554028100b377f13cbd1e1bbb0d8ce0 540 PRINTS PR01036 Tetracycline resistance protein TetB signature 417 436 3.8E-7 T 29-03-2018 SMALA_RS10975 b554028100b377f13cbd1e1bbb0d8ce0 540 PRINTS PR01036 Tetracycline resistance protein TetB signature 154 178 3.8E-7 T 29-03-2018 SMALA_RS10975 b554028100b377f13cbd1e1bbb0d8ce0 540 PRINTS PR01036 Tetracycline resistance protein TetB signature 319 343 3.8E-7 T 29-03-2018 SMALA_RS10975 b554028100b377f13cbd1e1bbb0d8ce0 540 PRINTS PR01036 Tetracycline resistance protein TetB signature 29 53 3.8E-7 T 29-03-2018 SMALA_RS10975 b554028100b377f13cbd1e1bbb0d8ce0 540 SUPERFAMILY SSF103473 491 516 3.53E-73 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS10975 b554028100b377f13cbd1e1bbb0d8ce0 540 SUPERFAMILY SSF103473 265 436 3.53E-73 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS10975 b554028100b377f13cbd1e1bbb0d8ce0 540 SUPERFAMILY SSF103473 11 213 3.53E-73 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS24720 ec4f9a7701b9f8cee405797dd401fc9e 282 Pfam PF13560 Helix-turn-helix domain 18 72 2.1E-10 T 29-03-2018 SMALA_RS24720 ec4f9a7701b9f8cee405797dd401fc9e 282 SUPERFAMILY SSF47413 18 69 6.82E-6 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS24720 ec4f9a7701b9f8cee405797dd401fc9e 282 Gene3D G3DSA:1.10.260.40 8 97 7.1E-9 T 29-03-2018 SMALA_RS24720 ec4f9a7701b9f8cee405797dd401fc9e 282 SMART SM00530 21 75 4.0E-6 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS38200 a144d89f09646305a0a5fc30fc0201e8 476 Gene3D G3DSA:3.30.470.20 175 458 1.1E-49 T 29-03-2018 SMALA_RS38200 a144d89f09646305a0a5fc30fc0201e8 476 SMART SM01209 170 346 0.0022 T 29-03-2018 SMALA_RS38200 a144d89f09646305a0a5fc30fc0201e8 476 SUPERFAMILY SSF56059 169 375 2.3E-42 T 29-03-2018 SMALA_RS38200 a144d89f09646305a0a5fc30fc0201e8 476 Gene3D G3DSA:3.40.50.20 48 174 3.5E-10 T 29-03-2018 SMALA_RS38200 a144d89f09646305a0a5fc30fc0201e8 476 Pfam PF13535 ATP-grasp domain 206 348 6.6E-21 T 29-03-2018 SMALA_RS40440 163f85d960c9f75138b8e323adfa2c28 398 Gene3D G3DSA:3.20.20.140 68 354 5.2E-43 T 29-03-2018 SMALA_RS40440 163f85d960c9f75138b8e323adfa2c28 398 Pfam PF01979 Amidohydrolase family 54 394 2.7E-40 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 SMALA_RS40440 163f85d960c9f75138b8e323adfa2c28 398 Gene3D G3DSA:2.30.40.10 1 67 3.7E-14 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS40440 163f85d960c9f75138b8e323adfa2c28 398 SUPERFAMILY SSF51338 3 57 5.4E-15 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS40440 163f85d960c9f75138b8e323adfa2c28 398 SUPERFAMILY SSF51338 358 396 5.4E-15 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS40440 163f85d960c9f75138b8e323adfa2c28 398 SUPERFAMILY SSF51556 57 358 6.51E-75 T 29-03-2018 IPR032466 Metal-dependent hydrolase SMALA_RS24990 915d30640c3ef519c268c64894e0eb0c 125 Gene3D G3DSA:3.40.50.1390 65 125 2.8E-6 T 29-03-2018 SMALA_RS30660 722891bff9ffa78ec737af761fa20d42 215 SMART SM00849 7 176 1.5E-5 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS30660 722891bff9ffa78ec737af761fa20d42 215 Pfam PF13483 Beta-lactamase superfamily domain 2 176 2.4E-22 T 29-03-2018 SMALA_RS30660 722891bff9ffa78ec737af761fa20d42 215 SUPERFAMILY SSF56281 1 178 7.47E-18 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS30660 722891bff9ffa78ec737af761fa20d42 215 Gene3D G3DSA:3.60.15.10 1 189 7.6E-20 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS27725 81bb72e9836429fd42065674b148865e 332 SUPERFAMILY SSF51735 3 183 6.73E-72 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS27725 81bb72e9836429fd42065674b148865e 332 Gene3D G3DSA:3.40.50.720 8 46 0.074 T 29-03-2018 SMALA_RS27725 81bb72e9836429fd42065674b148865e 332 SUPERFAMILY SSF48179 184 329 4.42E-69 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMALA_RS27725 81bb72e9836429fd42065674b148865e 332 PIRSF PIRSF000116 3 208 1.4E-39 T 29-03-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 SMALA_RS27725 81bb72e9836429fd42065674b148865e 332 PIRSF PIRSF000116 203 330 7.2E-13 T 29-03-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 SMALA_RS27725 81bb72e9836429fd42065674b148865e 332 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 15 178 1.8E-75 T 29-03-2018 IPR013116 Acetohydroxy acid isomeroreductase, NADPH-binding domain KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 SMALA_RS27725 81bb72e9836429fd42065674b148865e 332 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 2 329 44.858 T 29-03-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 SMALA_RS27725 81bb72e9836429fd42065674b148865e 332 Gene3D G3DSA:1.10.1040.10 56 331 2.1E-114 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMALA_RS27725 81bb72e9836429fd42065674b148865e 332 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 15 327 3.0E-132 T 29-03-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 SMALA_RS27725 81bb72e9836429fd42065674b148865e 332 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 184 327 2.9E-65 T 29-03-2018 IPR000506 Acetohydroxy acid isomeroreductase C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 SMALA_RS22035 b8f66876459bc80ff26282bc4b2a9a03 234 SUPERFAMILY SSF46689 18 99 2.98E-19 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS22035 b8f66876459bc80ff26282bc4b2a9a03 234 Pfam PF00440 Bacterial regulatory proteins, tetR family 32 77 9.3E-14 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS22035 b8f66876459bc80ff26282bc4b2a9a03 234 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 52 75 2.4E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS22035 b8f66876459bc80ff26282bc4b2a9a03 234 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 31 44 2.4E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS22035 b8f66876459bc80ff26282bc4b2a9a03 234 Gene3D G3DSA:1.10.10.60 15 52 5.7E-13 T 29-03-2018 SMALA_RS22035 b8f66876459bc80ff26282bc4b2a9a03 234 Gene3D G3DSA:1.10.260.40 53 82 5.3E-15 T 29-03-2018 SMALA_RS22035 b8f66876459bc80ff26282bc4b2a9a03 234 Gene3D G3DSA:1.10.357.10 83 225 2.4E-29 T 29-03-2018 SMALA_RS31560 6d9fd09df5edf6a317079135085769f5 185 SUPERFAMILY SSF48498 81 185 1.3E-21 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS31560 6d9fd09df5edf6a317079135085769f5 185 SUPERFAMILY SSF46689 7 73 1.8E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS31560 6d9fd09df5edf6a317079135085769f5 185 Gene3D G3DSA:1.10.10.60 2 59 1.3E-11 T 29-03-2018 SMALA_RS31560 6d9fd09df5edf6a317079135085769f5 185 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 58 1.2E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS31560 6d9fd09df5edf6a317079135085769f5 185 Gene3D G3DSA:1.10.357.10 60 185 6.5E-24 T 29-03-2018 SMALA_RS31515 176fbbf23dbedc841a3f70d68f77276a 469 Gene3D G3DSA:3.40.605.10 2 248 3.8E-72 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS31515 176fbbf23dbedc841a3f70d68f77276a 469 SUPERFAMILY SSF53720 6 457 6.94E-143 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMALA_RS31515 176fbbf23dbedc841a3f70d68f77276a 469 Pfam PF00171 Aldehyde dehydrogenase family 5 454 6.8E-139 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS31515 176fbbf23dbedc841a3f70d68f77276a 469 Gene3D G3DSA:3.40.309.10 249 440 9.8E-65 T 29-03-2018 SMALA_RS07135 5135b8e31b8f34863e55fa5a556f2974 606 Gene3D G3DSA:3.40.50.1820 4 273 9.4E-45 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS07135 5135b8e31b8f34863e55fa5a556f2974 606 Hamap MF_01282 Virginiamycin B lyase [vgb]. 307 604 43.278 T 29-03-2018 IPR011217 Streptogramin lyase GO:0000287|GO:0016835|GO:0017001|GO:0046677 SMALA_RS07135 5135b8e31b8f34863e55fa5a556f2974 606 Pfam PF07859 alpha/beta hydrolase fold 50 250 1.1E-48 T 29-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 SMALA_RS07135 5135b8e31b8f34863e55fa5a556f2974 606 SUPERFAMILY SSF63829 353 596 1.63E-33 T 29-03-2018 SMALA_RS07135 5135b8e31b8f34863e55fa5a556f2974 606 SUPERFAMILY SSF53474 25 268 1.93E-50 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS07135 5135b8e31b8f34863e55fa5a556f2974 606 Gene3D G3DSA:2.120.10.30 440 603 1.8E-17 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like SMALA_RS07135 5135b8e31b8f34863e55fa5a556f2974 606 Gene3D G3DSA:2.120.10.30 278 439 1.3E-13 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like SMALA_RS05245 2ec08151a80c243af83cff1158e3fdf0 271 Gene3D G3DSA:3.40.50.150 14 243 1.2E-33 T 29-03-2018 SMALA_RS05245 2ec08151a80c243af83cff1158e3fdf0 271 SMART SM00650 36 174 5.3E-4 T 29-03-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 SMALA_RS05245 2ec08151a80c243af83cff1158e3fdf0 271 Pfam PF08241 Methyltransferase domain 53 146 9.5E-18 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 SMALA_RS05245 2ec08151a80c243af83cff1158e3fdf0 271 SUPERFAMILY SSF53335 16 149 1.0E-34 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS12845 8ed3ce9c9c70e0daf2539683c8336f60 207 SUPERFAMILY SSF55729 5 162 5.12E-23 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS12845 8ed3ce9c9c70e0daf2539683c8336f60 207 Pfam PF13302 Acetyltransferase (GNAT) domain 10 157 1.5E-14 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SMALA_RS12845 8ed3ce9c9c70e0daf2539683c8336f60 207 Gene3D G3DSA:3.40.630.30 2 207 1.5E-33 T 29-03-2018 SMALA_RS01900 0cf4c88056e96710dc305cce6a39b6e6 290 Gene3D G3DSA:3.20.20.370 70 276 3.7E-35 T 29-03-2018 SMALA_RS01900 0cf4c88056e96710dc305cce6a39b6e6 290 Pfam PF01522 Polysaccharide deacetylase 82 203 2.5E-15 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 SMALA_RS01900 0cf4c88056e96710dc305cce6a39b6e6 290 SUPERFAMILY SSF88713 72 272 4.45E-38 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 SMALA_RS18235 cf089ee039026a485dc169f5c1ca5f61 270 Pfam PF13490 Putative zinc-finger 11 39 2.4E-7 T 29-03-2018 IPR027383 Putative zinc-finger SMALA_RS33315 7cf796a75649ccf44186212147ab9f31 282 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 141 162 - T 29-03-2018 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 SMALA_RS33315 7cf796a75649ccf44186212147ab9f31 282 Gene3D G3DSA:3.40.190.10 113 209 5.8E-17 T 29-03-2018 SMALA_RS33315 7cf796a75649ccf44186212147ab9f31 282 Pfam PF01634 ATP phosphoribosyltransferase 49 203 3.1E-41 T 29-03-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 SMALA_RS33315 7cf796a75649ccf44186212147ab9f31 282 SUPERFAMILY SSF53850 1 208 9.65E-59 T 29-03-2018 SMALA_RS33315 7cf796a75649ccf44186212147ab9f31 282 Gene3D G3DSA:3.40.190.10 1 112 1.0E-32 T 29-03-2018 SMALA_RS33315 7cf796a75649ccf44186212147ab9f31 282 Gene3D G3DSA:3.30.70.120 210 274 3.7E-24 T 29-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal SMALA_RS33315 7cf796a75649ccf44186212147ab9f31 282 SUPERFAMILY SSF54913 210 281 2.22E-20 T 29-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta SMALA_RS33315 7cf796a75649ccf44186212147ab9f31 282 Hamap MF_00079 ATP phosphoribosyltransferase [hisG]. 1 282 31.506 T 29-03-2018 IPR020621 ATP phosphoribosyltransferase HisG, long form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 SMALA_RS33315 7cf796a75649ccf44186212147ab9f31 282 Pfam PF08029 HisG, C-terminal domain 207 278 1.2E-24 T 29-03-2018 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 SMALA_RS33315 7cf796a75649ccf44186212147ab9f31 282 TIGRFAM TIGR03455 HisG_C-term: ATP phosphoribosyltransferase, C-terminal domain 191 281 2.2E-28 T 29-03-2018 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 SMALA_RS33315 7cf796a75649ccf44186212147ab9f31 282 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 2 182 9.8E-51 T 29-03-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 SMALA_RS27430 7120f7c3bc30aca0b9d74f81b1ffd26f 668 SUPERFAMILY SSF52540 419 658 2.01E-70 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS27430 7120f7c3bc30aca0b9d74f81b1ffd26f 668 SUPERFAMILY SSF90123 27 345 8.76E-70 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMALA_RS27430 7120f7c3bc30aca0b9d74f81b1ffd26f 668 Pfam PF00664 ABC transporter transmembrane region 44 310 1.5E-38 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMALA_RS27430 7120f7c3bc30aca0b9d74f81b1ffd26f 668 Gene3D G3DSA:1.20.1560.10 10 342 4.7E-58 T 29-03-2018 SMALA_RS27430 7120f7c3bc30aca0b9d74f81b1ffd26f 668 ProSitePatterns PS00211 ABC transporters family signature. 561 575 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS27430 7120f7c3bc30aca0b9d74f81b1ffd26f 668 Gene3D G3DSA:3.40.50.300 408 665 9.4E-62 T 29-03-2018 SMALA_RS27430 7120f7c3bc30aca0b9d74f81b1ffd26f 668 Pfam PF00005 ABC transporter 441 588 1.6E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS27430 7120f7c3bc30aca0b9d74f81b1ffd26f 668 SMART SM00382 450 629 7.7E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS07780 092394423152f80b0c25e224abce105b 714 Pfam PF09364 XFP N-terminal domain 34 369 5.9E-70 T 29-03-2018 IPR018970 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, N-terminal SMALA_RS07780 092394423152f80b0c25e224abce105b 714 Pfam PF09363 XFP C-terminal domain 563 690 5.1E-27 T 29-03-2018 IPR018969 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, C-terminal GO:0005975|GO:0016832 SMALA_RS07780 092394423152f80b0c25e224abce105b 714 SUPERFAMILY SSF52518 33 359 8.7E-31 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold SMALA_RS07780 092394423152f80b0c25e224abce105b 714 SUPERFAMILY SSF52518 391 555 2.82E-9 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold SMALA_RS07780 092394423152f80b0c25e224abce105b 714 ProSitePatterns PS60003 Phosphoketolase signature 2. 178 196 - T 29-03-2018 IPR019789 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, thiamine diphosphate binding site GO:0005975|GO:0016832 SMALA_RS07780 092394423152f80b0c25e224abce105b 714 Gene3D G3DSA:3.40.50.920 570 713 4.0E-31 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMALA_RS07780 092394423152f80b0c25e224abce105b 714 Gene3D G3DSA:3.40.50.970 18 374 3.6E-43 T 29-03-2018 SMALA_RS07780 092394423152f80b0c25e224abce105b 714 Pfam PF03894 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase 429 537 9.3E-27 T 29-03-2018 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 SMALA_RS07780 092394423152f80b0c25e224abce105b 714 Gene3D G3DSA:3.40.50.970 375 561 5.2E-12 T 29-03-2018 SMALA_RS12200 7118da0c14473089dab65c8af518865f 251 Pfam PF00583 Acetyltransferase (GNAT) family 160 238 1.6E-9 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SMALA_RS12200 7118da0c14473089dab65c8af518865f 251 SUPERFAMILY SSF55729 67 246 3.01E-21 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS12200 7118da0c14473089dab65c8af518865f 251 Gene3D G3DSA:3.40.630.30 111 250 3.2E-22 T 29-03-2018 SMALA_RS09895 0120823c104d7ab51aa904cedd8eb24b 265 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 74 79 - T 29-03-2018 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 SMALA_RS09895 0120823c104d7ab51aa904cedd8eb24b 265 SMART SM00020 41 256 5.5E-62 T 29-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 SMALA_RS09895 0120823c104d7ab51aa904cedd8eb24b 265 Pfam PF00089 Trypsin 42 254 7.5E-51 T 29-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 SMALA_RS09895 0120823c104d7ab51aa904cedd8eb24b 265 Gene3D G3DSA:2.40.10.10 132 262 7.7E-38 T 29-03-2018 SMALA_RS09895 0120823c104d7ab51aa904cedd8eb24b 265 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 206 217 - T 29-03-2018 IPR033116 Serine proteases, trypsin family, serine active site SMALA_RS09895 0120823c104d7ab51aa904cedd8eb24b 265 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 205 217 3.5E-12 T 29-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 SMALA_RS09895 0120823c104d7ab51aa904cedd8eb24b 265 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 119 133 3.5E-12 T 29-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 SMALA_RS09895 0120823c104d7ab51aa904cedd8eb24b 265 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 64 79 3.5E-12 T 29-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 SMALA_RS09895 0120823c104d7ab51aa904cedd8eb24b 265 Gene3D G3DSA:2.40.10.10 70 131 8.3E-14 T 29-03-2018 SMALA_RS09895 0120823c104d7ab51aa904cedd8eb24b 265 SUPERFAMILY SSF50494 42 256 2.28E-59 T 29-03-2018 IPR009003 Peptidase S1, PA clan SMALA_RS09895 0120823c104d7ab51aa904cedd8eb24b 265 Gene3D G3DSA:2.40.10.10 42 69 8.0E-12 T 29-03-2018 SMALA_RS34310 a80f8f8375e11b1c56d59c077a3004a5 476 Pfam PF02447 GntP family permease 8 474 3.1E-115 T 29-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 SMALA_RS34310 a80f8f8375e11b1c56d59c077a3004a5 476 PIRSF PIRSF002746 3 476 9.6E-135 T 29-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 SMALA_RS34310 a80f8f8375e11b1c56d59c077a3004a5 476 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 10 476 3.2E-112 T 29-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 SMALA_RS41610 33c7d6ea18791e8506683fbb1037704b 537 SUPERFAMILY SSF53822 253 494 6.85E-20 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SMALA_RS41610 33c7d6ea18791e8506683fbb1037704b 537 Pfam PF13407 Periplasmic binding protein domain 254 491 5.6E-12 T 29-03-2018 IPR025997 Periplasmic binding protein SMALA_RS41610 33c7d6ea18791e8506683fbb1037704b 537 Gene3D G3DSA:3.40.50.2300 229 354 1.9E-10 T 29-03-2018 SMALA_RS41610 33c7d6ea18791e8506683fbb1037704b 537 Gene3D G3DSA:3.40.50.2300 355 513 4.2E-8 T 29-03-2018 SMALA_RS15560 66e1fa15f9dd46a9ebea7a8c7a592fe3 1011 Pfam PF01580 FtsK/SpoIIIE family 598 705 5.3E-15 T 29-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 SMALA_RS15560 66e1fa15f9dd46a9ebea7a8c7a592fe3 1011 SUPERFAMILY SSF52540 575 709 5.01E-12 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS15560 66e1fa15f9dd46a9ebea7a8c7a592fe3 1011 SUPERFAMILY SSF52540 787 866 5.01E-12 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS15560 66e1fa15f9dd46a9ebea7a8c7a592fe3 1011 Gene3D G3DSA:3.40.50.300 575 873 1.0E-11 T 29-03-2018 SMALA_RS16330 4dc2b95198f26488ef25ee6445993f4b 392 Gene3D G3DSA:3.30.70.1230 188 390 1.1E-28 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 SMALA_RS16330 4dc2b95198f26488ef25ee6445993f4b 392 SUPERFAMILY SSF55073 205 339 2.98E-31 T 29-03-2018 IPR029787 Nucleotide cyclase SMALA_RS16330 4dc2b95198f26488ef25ee6445993f4b 392 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 207 336 8.2E-14 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 SMALA_RS16330 4dc2b95198f26488ef25ee6445993f4b 392 SMART SM00044 92 345 7.5E-4 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 SMALA_RS16330 4dc2b95198f26488ef25ee6445993f4b 392 Pfam PF16701 Adenylate cyclase regulatory domain 55 183 2.8E-8 T 29-03-2018 IPR032026 Adenylate cyclase regulatory domain SMALA_RS14705 837fc8654ecbd6ae3b25251abd31f943 135 Gene3D G3DSA:3.40.1260.10 7 131 6.1E-14 T 29-03-2018 SMALA_RS14705 837fc8654ecbd6ae3b25251abd31f943 135 SUPERFAMILY SSF75169 10 130 2.75E-11 T 29-03-2018 IPR027396 DsrEFH-like SMALA_RS14705 837fc8654ecbd6ae3b25251abd31f943 135 Pfam PF02635 DsrE/DsrF-like family 15 111 3.2E-6 T 29-03-2018 IPR003787 Sulphur relay, DsrE/F-like protein SMALA_RS21720 dacad3badf1195a2410126eb088843a8 512 Pfam PF00916 Sulfate permease family 24 391 6.9E-57 T 29-03-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 SMALA_RS36115 ca7487ab43b203c5b54d3e9218c4dad4 247 Pfam PF07848 PaaX-like protein 14 74 5.8E-12 T 29-03-2018 IPR012906 PaaX-like, N-terminal SMALA_RS36115 ca7487ab43b203c5b54d3e9218c4dad4 247 Pfam PF08223 PaaX-like protein C-terminal domain 186 237 6.6E-7 T 29-03-2018 IPR013225 PaaX-like, C-terminal SMALA_RS18460 315292e8e6c0a49675b58b98ac05a8ce 347 SUPERFAMILY SSF52343 127 249 5.63E-25 T 29-03-2018 SMALA_RS18460 315292e8e6c0a49675b58b98ac05a8ce 347 Gene3D G3DSA:2.40.30.10 28 129 1.3E-17 T 29-03-2018 SMALA_RS18460 315292e8e6c0a49675b58b98ac05a8ce 347 Pfam PF00970 Oxidoreductase FAD-binding domain 38 132 2.7E-5 T 29-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 SMALA_RS18460 315292e8e6c0a49675b58b98ac05a8ce 347 PRINTS PR00409 Phthalate dioxygenase reductase family signature 165 174 9.1E-31 T 29-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 SMALA_RS18460 315292e8e6c0a49675b58b98ac05a8ce 347 PRINTS PR00409 Phthalate dioxygenase reductase family signature 81 95 9.1E-31 T 29-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 SMALA_RS18460 315292e8e6c0a49675b58b98ac05a8ce 347 PRINTS PR00409 Phthalate dioxygenase reductase family signature 69 81 9.1E-31 T 29-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 SMALA_RS18460 315292e8e6c0a49675b58b98ac05a8ce 347 PRINTS PR00409 Phthalate dioxygenase reductase family signature 105 119 9.1E-31 T 29-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 SMALA_RS18460 315292e8e6c0a49675b58b98ac05a8ce 347 PRINTS PR00409 Phthalate dioxygenase reductase family signature 59 69 9.1E-31 T 29-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 SMALA_RS18460 315292e8e6c0a49675b58b98ac05a8ce 347 PRINTS PR00409 Phthalate dioxygenase reductase family signature 140 159 9.1E-31 T 29-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 SMALA_RS18460 315292e8e6c0a49675b58b98ac05a8ce 347 PRINTS PR00409 Phthalate dioxygenase reductase family signature 216 224 9.1E-31 T 29-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 SMALA_RS18460 315292e8e6c0a49675b58b98ac05a8ce 347 SUPERFAMILY SSF63380 35 129 9.01E-27 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 SMALA_RS18460 315292e8e6c0a49675b58b98ac05a8ce 347 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 294 302 - T 29-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 SMALA_RS18460 315292e8e6c0a49675b58b98ac05a8ce 347 Gene3D G3DSA:3.10.20.30 252 341 1.5E-18 T 29-03-2018 IPR012675 Beta-grasp domain SMALA_RS18460 315292e8e6c0a49675b58b98ac05a8ce 347 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 264 336 9.5E-12 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SMALA_RS18460 315292e8e6c0a49675b58b98ac05a8ce 347 SUPERFAMILY SSF54292 237 340 2.62E-25 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SMALA_RS18460 315292e8e6c0a49675b58b98ac05a8ce 347 Gene3D G3DSA:3.40.50.80 130 251 1.9E-15 T 29-03-2018 SMALA_RS11105 ca72d08c27df230348d71e559194282f 349 Pfam PF01497 Periplasmic binding protein 91 322 1.2E-31 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 SMALA_RS11105 ca72d08c27df230348d71e559194282f 349 Gene3D G3DSA:3.40.50.1980 88 191 7.6E-23 T 29-03-2018 SMALA_RS11105 ca72d08c27df230348d71e559194282f 349 SUPERFAMILY SSF53807 89 345 1.1E-43 T 29-03-2018 SMALA_RS11105 ca72d08c27df230348d71e559194282f 349 Gene3D G3DSA:3.40.50.1980 192 348 1.0E-29 T 29-03-2018 SMALA_RS10965 e96824e13f6e491f44fb162e07311231 342 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 132 333 4.2E-9 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMALA_RS10965 e96824e13f6e491f44fb162e07311231 342 Gene3D G3DSA:3.60.10.10 119 341 4.2E-20 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMALA_RS10965 e96824e13f6e491f44fb162e07311231 342 SUPERFAMILY SSF56219 126 341 4.97E-24 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMALA_RS08580 ca81a9149c97a1c1c22980e6cc59d1a4 71 Pfam PF11720 Peptidase inhibitor I78 family 17 62 4.4E-6 T 29-03-2018 IPR021719 Proteinase inhibitor I78 SMALA_RS13960 9aa1b8a18e7a3ffef6501ad88845b05b 308 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 253 266 - T 29-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 SMALA_RS13960 9aa1b8a18e7a3ffef6501ad88845b05b 308 TIGRFAM TIGR02152 D_ribokin_bact: ribokinase 7 306 8.0E-92 T 29-03-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 SMALA_RS13960 9aa1b8a18e7a3ffef6501ad88845b05b 308 SUPERFAMILY SSF53613 4 307 4.83E-78 T 29-03-2018 IPR029056 Ribokinase-like SMALA_RS13960 9aa1b8a18e7a3ffef6501ad88845b05b 308 Hamap MF_01987 Ribokinase [rbsK]. 4 308 26.068 T 29-03-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 SMALA_RS13960 9aa1b8a18e7a3ffef6501ad88845b05b 308 Pfam PF00294 pfkB family carbohydrate kinase 6 301 4.7E-65 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB SMALA_RS13960 9aa1b8a18e7a3ffef6501ad88845b05b 308 PRINTS PR00990 Ribokinase signature 224 235 7.9E-34 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 SMALA_RS13960 9aa1b8a18e7a3ffef6501ad88845b05b 308 PRINTS PR00990 Ribokinase signature 8 29 7.9E-34 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 SMALA_RS13960 9aa1b8a18e7a3ffef6501ad88845b05b 308 PRINTS PR00990 Ribokinase signature 35 54 7.9E-34 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 SMALA_RS13960 9aa1b8a18e7a3ffef6501ad88845b05b 308 PRINTS PR00990 Ribokinase signature 106 119 7.9E-34 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 SMALA_RS13960 9aa1b8a18e7a3ffef6501ad88845b05b 308 PRINTS PR00990 Ribokinase signature 179 194 7.9E-34 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 SMALA_RS13960 9aa1b8a18e7a3ffef6501ad88845b05b 308 Gene3D G3DSA:3.40.1190.20 1 308 9.0E-81 T 29-03-2018 IPR029056 Ribokinase-like SMALA_RS23040 aabad197915db0f0628da575ac892548 303 Gene3D G3DSA:3.40.50.720 3 271 3.0E-51 T 29-03-2018 SMALA_RS23040 aabad197915db0f0628da575ac892548 303 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 92 103 4.8E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS23040 aabad197915db0f0628da575ac892548 303 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 227 4.8E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS23040 aabad197915db0f0628da575ac892548 303 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 139 155 4.8E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS23040 aabad197915db0f0628da575ac892548 303 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 183 4.8E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS23040 aabad197915db0f0628da575ac892548 303 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 4.8E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS23040 aabad197915db0f0628da575ac892548 303 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 185 202 4.8E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS23040 aabad197915db0f0628da575ac892548 303 SUPERFAMILY SSF51735 5 248 5.63E-56 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS23040 aabad197915db0f0628da575ac892548 303 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 241 2.7E-37 T 29-03-2018 SMALA_RS23040 aabad197915db0f0628da575ac892548 303 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 198 1.6E-4 T 29-03-2018 SMALA_RS33425 fc45e48a184021ab100e69de5f6015c5 581 Gene3D G3DSA:2.40.110.10 135 233 9.4E-16 T 29-03-2018 SMALA_RS33425 fc45e48a184021ab100e69de5f6015c5 581 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 243 380 1.7E-12 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMALA_RS33425 fc45e48a184021ab100e69de5f6015c5 581 SUPERFAMILY SSF47203 243 379 2.9E-16 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMALA_RS33425 fc45e48a184021ab100e69de5f6015c5 581 Gene3D G3DSA:1.10.540.10 10 134 1.1E-5 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS33425 fc45e48a184021ab100e69de5f6015c5 581 Gene3D G3DSA:1.20.140.10 234 383 3.3E-19 T 29-03-2018 SMALA_RS33425 fc45e48a184021ab100e69de5f6015c5 581 SUPERFAMILY SSF56645 41 243 1.7E-30 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMALA_RS30255 d11d4e1cd07099c81df8df9eab1da8c4 466 Pfam PF00009 Elongation factor Tu GTP binding domain 25 219 7.9E-40 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMALA_RS30255 d11d4e1cd07099c81df8df9eab1da8c4 466 Gene3D G3DSA:2.40.30.10 340 444 3.9E-21 T 29-03-2018 SMALA_RS30255 d11d4e1cd07099c81df8df9eab1da8c4 466 SUPERFAMILY SSF50465 342 443 1.97E-24 T 29-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal SMALA_RS30255 d11d4e1cd07099c81df8df9eab1da8c4 466 SUPERFAMILY SSF52540 24 258 3.89E-53 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS30255 d11d4e1cd07099c81df8df9eab1da8c4 466 SUPERFAMILY SSF50447 248 340 3.95E-19 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain SMALA_RS30255 d11d4e1cd07099c81df8df9eab1da8c4 466 PRINTS PR00315 GTP-binding elongation factor signature 105 115 3.0E-12 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMALA_RS30255 d11d4e1cd07099c81df8df9eab1da8c4 466 PRINTS PR00315 GTP-binding elongation factor signature 158 167 3.0E-12 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMALA_RS30255 d11d4e1cd07099c81df8df9eab1da8c4 466 PRINTS PR00315 GTP-binding elongation factor signature 85 93 3.0E-12 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMALA_RS30255 d11d4e1cd07099c81df8df9eab1da8c4 466 PRINTS PR00315 GTP-binding elongation factor signature 26 39 3.0E-12 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMALA_RS30255 d11d4e1cd07099c81df8df9eab1da8c4 466 PRINTS PR00315 GTP-binding elongation factor signature 121 132 3.0E-12 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMALA_RS30255 d11d4e1cd07099c81df8df9eab1da8c4 466 TIGRFAM TIGR02034 CysN: sulfate adenylyltransferase, large subunit 25 443 1.7E-159 T 29-03-2018 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 SMALA_RS30255 d11d4e1cd07099c81df8df9eab1da8c4 466 Gene3D G3DSA:2.40.30.10 245 338 3.0E-20 T 29-03-2018 SMALA_RS30255 d11d4e1cd07099c81df8df9eab1da8c4 466 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 78 93 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site SMALA_RS30255 d11d4e1cd07099c81df8df9eab1da8c4 466 Gene3D G3DSA:3.40.50.300 20 243 1.4E-35 T 29-03-2018 SMALA_RS18595 fd82ab2475c7bec1bce26a1a4e73ad1f 653 Gene3D G3DSA:2.30.38.10 431 518 2.6E-10 T 29-03-2018 SMALA_RS18595 fd82ab2475c7bec1bce26a1a4e73ad1f 653 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 26 644 7.8E-295 T 29-03-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 SMALA_RS18595 fd82ab2475c7bec1bce26a1a4e73ad1f 653 Gene3D G3DSA:3.30.300.30 519 630 1.4E-29 T 29-03-2018 SMALA_RS18595 fd82ab2475c7bec1bce26a1a4e73ad1f 653 SUPERFAMILY SSF56801 31 642 6.67E-177 T 29-03-2018 SMALA_RS18595 fd82ab2475c7bec1bce26a1a4e73ad1f 653 Pfam PF13193 AMP-binding enzyme C-terminal domain 534 612 9.8E-27 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS18595 fd82ab2475c7bec1bce26a1a4e73ad1f 653 Gene3D G3DSA:3.40.50.980 76 268 8.1E-53 T 29-03-2018 SMALA_RS18595 fd82ab2475c7bec1bce26a1a4e73ad1f 653 Gene3D G3DSA:3.40.50.980 269 430 4.9E-37 T 29-03-2018 SMALA_RS18595 fd82ab2475c7bec1bce26a1a4e73ad1f 653 Hamap MF_01123 Acetyl-coenzyme A synthetase [acs]. 11 646 50.77 T 29-03-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 SMALA_RS18595 fd82ab2475c7bec1bce26a1a4e73ad1f 653 Pfam PF00501 AMP-binding enzyme 91 525 1.7E-93 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS18595 fd82ab2475c7bec1bce26a1a4e73ad1f 653 ProSitePatterns PS00455 Putative AMP-binding domain signature. 263 274 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS18595 fd82ab2475c7bec1bce26a1a4e73ad1f 653 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 31 83 2.1E-21 T 29-03-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 SMALA_RS20480 5a279aebc2fe9811c836d02b8dca3e6e 231 ProSitePatterns PS00776 Glycosyl hydrolases family 11 (GH11) active site signature 1. 124 134 - T 29-03-2018 IPR018208 Glycoside hydrolase family 11, active site 1 MetaCyc: PWY-6784 SMALA_RS20480 5a279aebc2fe9811c836d02b8dca3e6e 231 Pfam PF00457 Glycosyl hydrolases family 11 53 227 1.3E-75 T 29-03-2018 IPR033123 Glycosyl hydrolases family 11 (GH11) domain MetaCyc: PWY-6784 SMALA_RS20480 5a279aebc2fe9811c836d02b8dca3e6e 231 SUPERFAMILY SSF49899 42 230 4.01E-77 T 29-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain SMALA_RS20480 5a279aebc2fe9811c836d02b8dca3e6e 231 Gene3D G3DSA:2.60.120.180 38 231 6.5E-82 T 29-03-2018 IPR013319 Glycoside hydrolase family 11/12 GO:0004553 MetaCyc: PWY-6784 SMALA_RS20480 5a279aebc2fe9811c836d02b8dca3e6e 231 ProSitePatterns PS00777 Glycosyl hydrolases family 11 (GH11) active site signature 2. 214 225 - T 29-03-2018 IPR033119 Glycoside hydrolase family 11, active site 2 MetaCyc: PWY-6784 SMALA_RS20480 5a279aebc2fe9811c836d02b8dca3e6e 231 PRINTS PR00911 Glycosyl hydrolase family 11 signature 114 123 5.0E-18 T 29-03-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6784 SMALA_RS20480 5a279aebc2fe9811c836d02b8dca3e6e 231 PRINTS PR00911 Glycosyl hydrolase family 11 signature 198 206 5.0E-18 T 29-03-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6784 SMALA_RS20480 5a279aebc2fe9811c836d02b8dca3e6e 231 PRINTS PR00911 Glycosyl hydrolase family 11 signature 150 156 5.0E-18 T 29-03-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6784 SMALA_RS20480 5a279aebc2fe9811c836d02b8dca3e6e 231 PRINTS PR00911 Glycosyl hydrolase family 11 signature 170 175 5.0E-18 T 29-03-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6784 SMALA_RS20480 5a279aebc2fe9811c836d02b8dca3e6e 231 PRINTS PR00911 Glycosyl hydrolase family 11 signature 175 184 5.0E-18 T 29-03-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6784 SMALA_RS20480 5a279aebc2fe9811c836d02b8dca3e6e 231 PRINTS PR00911 Glycosyl hydrolase family 11 signature 124 134 5.0E-18 T 29-03-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6784 SMALA_RS31135 25d65e564a4953d794efdc823c08fb63 251 Pfam PF12697 Alpha/beta hydrolase family 30 241 3.8E-12 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS31135 25d65e564a4953d794efdc823c08fb63 251 Gene3D G3DSA:3.40.50.1820 3 250 2.1E-38 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS31135 25d65e564a4953d794efdc823c08fb63 251 SUPERFAMILY SSF53474 10 247 1.24E-42 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS40850 42d0462d7cdf9c1837942c1f518fdd49 294 Gene3D G3DSA:3.20.20.380 140 292 2.6E-22 T 29-03-2018 SMALA_RS40850 42d0462d7cdf9c1837942c1f518fdd49 294 ProDom PD011184 BTPA I PHOTOSYSTEM BIOGENESIS ASSEMBLY SGCQ TRIPHOSPHATASE NUCLEOSIDE PAE3553 ENZYME 50 233 1.0E-49 T 29-03-2018 IPR005137 Membrane complex biogenesis protein, BtpA family SMALA_RS40850 42d0462d7cdf9c1837942c1f518fdd49 294 SUPERFAMILY SSF51366 17 287 1.58E-21 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 SMALA_RS40850 42d0462d7cdf9c1837942c1f518fdd49 294 PIRSF PIRSF005956 18 291 4.0E-85 T 29-03-2018 IPR005137 Membrane complex biogenesis protein, BtpA family SMALA_RS40850 42d0462d7cdf9c1837942c1f518fdd49 294 TIGRFAM TIGR00259 thylakoid_BtpA: membrane complex biogenesis protein, BtpA family 28 288 2.8E-57 T 29-03-2018 IPR005137 Membrane complex biogenesis protein, BtpA family SMALA_RS40850 42d0462d7cdf9c1837942c1f518fdd49 294 Pfam PF03437 BtpA family 28 287 1.5E-63 T 29-03-2018 IPR005137 Membrane complex biogenesis protein, BtpA family SMALA_RS40850 42d0462d7cdf9c1837942c1f518fdd49 294 Gene3D G3DSA:3.20.20.60 47 126 0.04 T 29-03-2018 SMALA_RS29415 2404fae36cda3890a57b4dc07a5b2c81 377 SUPERFAMILY SSF53901 184 375 9.36E-52 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS29415 2404fae36cda3890a57b4dc07a5b2c81 377 Gene3D G3DSA:3.40.47.10 226 376 1.5E-41 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS29415 2404fae36cda3890a57b4dc07a5b2c81 377 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 221 332 1.1E-29 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS29415 2404fae36cda3890a57b4dc07a5b2c81 377 Gene3D G3DSA:3.40.47.10 2 217 9.7E-31 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS29415 2404fae36cda3890a57b4dc07a5b2c81 377 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 6 216 1.2E-17 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS29415 2404fae36cda3890a57b4dc07a5b2c81 377 SUPERFAMILY SSF53901 6 216 2.2E-30 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS29415 2404fae36cda3890a57b4dc07a5b2c81 377 SMART SM00825 Beta-ketoacyl synthase 10 377 5.3E-13 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS20475 1af7cb84c09bac796bc7405542d838ce 387 Gene3D G3DSA:3.40.50.2000 153 355 1.2E-6 T 29-03-2018 SMALA_RS20475 1af7cb84c09bac796bc7405542d838ce 387 SUPERFAMILY SSF53756 4 288 1.88E-9 T 29-03-2018 SMALA_RS09120 7518b238a1839f66890dc49f125031b6 164 Gene3D G3DSA:3.40.50.2300 1 162 9.0E-36 T 29-03-2018 SMALA_RS09120 7518b238a1839f66890dc49f125031b6 164 SMART SM00448 9 123 2.8E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS09120 7518b238a1839f66890dc49f125031b6 164 Pfam PF00072 Response regulator receiver domain 11 123 2.4E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS09120 7518b238a1839f66890dc49f125031b6 164 SUPERFAMILY SSF52172 8 157 2.28E-36 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS12920 12036dc30b971dc196b7a4f0dbbaa72a 361 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 260 273 - T 29-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 SMALA_RS12920 12036dc30b971dc196b7a4f0dbbaa72a 361 Gene3D G3DSA:3.40.1190.20 20 324 4.3E-58 T 29-03-2018 IPR029056 Ribokinase-like SMALA_RS12920 12036dc30b971dc196b7a4f0dbbaa72a 361 SUPERFAMILY SSF53613 22 316 1.71E-52 T 29-03-2018 IPR029056 Ribokinase-like SMALA_RS12920 12036dc30b971dc196b7a4f0dbbaa72a 361 Pfam PF00294 pfkB family carbohydrate kinase 50 307 6.5E-35 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB SMALA_RS34730 74a53e533a6018c7a1103f2f1a0ef1ab 438 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 252 289 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMALA_RS34730 74a53e533a6018c7a1103f2f1a0ef1ab 438 SUPERFAMILY SSF53383 9 434 4.34E-112 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS34730 74a53e533a6018c7a1103f2f1a0ef1ab 438 Gene3D G3DSA:3.90.1150.10 5 178 6.1E-41 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS34730 74a53e533a6018c7a1103f2f1a0ef1ab 438 Hamap MF_00834 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [bioA]. 6 437 48.351 T 29-03-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 SMALA_RS34730 74a53e533a6018c7a1103f2f1a0ef1ab 438 Gene3D G3DSA:3.90.1150.10 327 438 3.8E-24 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS34730 74a53e533a6018c7a1103f2f1a0ef1ab 438 Pfam PF00202 Aminotransferase class-III 31 431 4.4E-112 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMALA_RS34730 74a53e533a6018c7a1103f2f1a0ef1ab 438 TIGRFAM TIGR00508 bioA: adenosylmethionine-8-amino-7-oxononanoate transaminase 18 433 1.7E-162 T 29-03-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 SMALA_RS34730 74a53e533a6018c7a1103f2f1a0ef1ab 438 Gene3D G3DSA:3.40.640.10 198 326 9.9E-38 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS39735 9d24c3c38d9e8b87ef23b738fc1b9ccd 191 SUPERFAMILY SSF48498 76 184 2.99E-13 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS39735 9d24c3c38d9e8b87ef23b738fc1b9ccd 191 Gene3D G3DSA:1.10.260.40 35 61 2.9E-11 T 29-03-2018 SMALA_RS39735 9d24c3c38d9e8b87ef23b738fc1b9ccd 191 Gene3D G3DSA:1.10.10.60 1 34 2.6E-13 T 29-03-2018 SMALA_RS39735 9d24c3c38d9e8b87ef23b738fc1b9ccd 191 SUPERFAMILY SSF46689 3 81 8.21E-19 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS39735 9d24c3c38d9e8b87ef23b738fc1b9ccd 191 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 59 1.7E-13 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS39735 9d24c3c38d9e8b87ef23b738fc1b9ccd 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 5.3E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS39735 9d24c3c38d9e8b87ef23b738fc1b9ccd 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 5.3E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS39735 9d24c3c38d9e8b87ef23b738fc1b9ccd 191 Gene3D G3DSA:1.10.357.10 62 188 5.8E-9 T 29-03-2018 SMALA_RS37410 9fa73804cc00b8ad3b9d64d6d0e7cd01 243 SUPERFAMILY SSF143631 1 237 4.18E-54 T 29-03-2018 IPR003374 ApbE-like domain SMALA_RS37410 9fa73804cc00b8ad3b9d64d6d0e7cd01 243 Pfam PF02424 ApbE family 83 216 6.2E-31 T 29-03-2018 IPR024932 Flavin transferase ApbE GO:0017013 SMALA_RS37410 9fa73804cc00b8ad3b9d64d6d0e7cd01 243 Pfam PF02424 ApbE family 1 82 1.9E-7 T 29-03-2018 IPR024932 Flavin transferase ApbE GO:0017013 SMALA_RS37410 9fa73804cc00b8ad3b9d64d6d0e7cd01 243 Gene3D G3DSA:3.10.520.10 9 238 1.4E-56 T 29-03-2018 SMALA_RS12945 07cf9babc988286c6767572b7c88da09 363 Gene3D G3DSA:3.20.20.70 8 359 1.8E-52 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS12945 07cf9babc988286c6767572b7c88da09 363 Pfam PF03060 Nitronate monooxygenase 3 343 1.9E-106 T 29-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 SMALA_RS12945 07cf9babc988286c6767572b7c88da09 363 SUPERFAMILY SSF51412 99 344 1.98E-59 T 29-03-2018 SMALA_RS12945 07cf9babc988286c6767572b7c88da09 363 SUPERFAMILY SSF51412 9 72 1.98E-59 T 29-03-2018 SMALA_RS27575 a1e96f405c26cbdc331b6618db4f754a 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 37 52 3.9E-12 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS27575 a1e96f405c26cbdc331b6618db4f754a 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 5 20 3.9E-12 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS27575 a1e96f405c26cbdc331b6618db4f754a 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 52 67 3.9E-12 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS27575 a1e96f405c26cbdc331b6618db4f754a 118 SMART SM00418 3 81 1.5E-23 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS27575 a1e96f405c26cbdc331b6618db4f754a 118 Gene3D G3DSA:1.10.10.10 1 103 8.2E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS27575 a1e96f405c26cbdc331b6618db4f754a 118 Pfam PF01022 Bacterial regulatory protein, arsR family 11 55 3.3E-16 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS27575 a1e96f405c26cbdc331b6618db4f754a 118 SUPERFAMILY SSF46785 5 96 3.25E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS21220 15c1e9edcc3d586bacf971f0e56f39d6 241 Gene3D G3DSA:1.10.357.10 89 241 2.7E-33 T 29-03-2018 SMALA_RS21220 15c1e9edcc3d586bacf971f0e56f39d6 241 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 56 79 8.0E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS21220 15c1e9edcc3d586bacf971f0e56f39d6 241 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 49 8.0E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS21220 15c1e9edcc3d586bacf971f0e56f39d6 241 Pfam PF00440 Bacterial regulatory proteins, tetR family 37 80 4.4E-13 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS21220 15c1e9edcc3d586bacf971f0e56f39d6 241 SUPERFAMILY SSF48498 161 237 1.17E-13 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS21220 15c1e9edcc3d586bacf971f0e56f39d6 241 SUPERFAMILY SSF46689 24 106 1.65E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS21220 15c1e9edcc3d586bacf971f0e56f39d6 241 Gene3D G3DSA:1.10.10.60 14 67 1.3E-14 T 29-03-2018 SMALA_RS21220 15c1e9edcc3d586bacf971f0e56f39d6 241 Gene3D G3DSA:1.10.10.60 68 88 7.7E-10 T 29-03-2018 SMALA_RS32460 c8283d9e8228ef559856792801d7b361 198 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 9 102 6.2E-12 T 29-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 SMALA_RS32460 c8283d9e8228ef559856792801d7b361 198 SUPERFAMILY SSF50475 7 117 7.12E-11 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS32460 c8283d9e8228ef559856792801d7b361 198 Gene3D G3DSA:2.30.110.10 1 139 6.5E-20 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS06570 25d48a1a01d1cfa282677af3e74af674 517 Pfam PF13193 AMP-binding enzyme C-terminal domain 424 498 5.6E-23 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS06570 25d48a1a01d1cfa282677af3e74af674 517 Gene3D G3DSA:3.40.50.980 167 319 1.4E-39 T 29-03-2018 SMALA_RS06570 25d48a1a01d1cfa282677af3e74af674 517 Gene3D G3DSA:3.30.300.30 411 508 9.8E-29 T 29-03-2018 SMALA_RS06570 25d48a1a01d1cfa282677af3e74af674 517 Gene3D G3DSA:3.40.50.980 9 166 1.9E-36 T 29-03-2018 SMALA_RS06570 25d48a1a01d1cfa282677af3e74af674 517 SUPERFAMILY SSF56801 7 511 3.4E-137 T 29-03-2018 SMALA_RS06570 25d48a1a01d1cfa282677af3e74af674 517 Gene3D G3DSA:2.30.38.10 320 408 1.5E-17 T 29-03-2018 SMALA_RS06570 25d48a1a01d1cfa282677af3e74af674 517 Pfam PF00501 AMP-binding enzyme 16 415 3.6E-87 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS06570 25d48a1a01d1cfa282677af3e74af674 517 ProSitePatterns PS00455 Putative AMP-binding domain signature. 161 172 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS23545 e9e3b510c8d7d02e3a02a4a242e3df79 281 Pfam PF00378 Enoyl-CoA hydratase/isomerase 59 263 2.0E-22 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 SMALA_RS23545 e9e3b510c8d7d02e3a02a4a242e3df79 281 SUPERFAMILY SSF52096 20 250 1.37E-41 T 29-03-2018 IPR029045 ClpP/crotonase-like domain SMALA_RS23545 e9e3b510c8d7d02e3a02a4a242e3df79 281 Gene3D G3DSA:3.90.226.10 19 268 2.8E-29 T 29-03-2018 SMALA_RS23365 9332b4f20140d0d78fcc7838d298127b 157 Gene3D G3DSA:3.10.129.10 2 141 5.1E-26 T 29-03-2018 SMALA_RS23365 9332b4f20140d0d78fcc7838d298127b 157 Pfam PF13279 Thioesterase-like superfamily 12 133 8.9E-22 T 29-03-2018 SMALA_RS23365 9332b4f20140d0d78fcc7838d298127b 157 SUPERFAMILY SSF54637 7 150 7.04E-39 T 29-03-2018 IPR029069 HotDog domain SMALA_RS39630 40f523d8ce6bbee72eadaf30473752bf 412 Gene3D G3DSA:3.40.50.10540 19 412 9.3E-126 T 29-03-2018 IPR023606 CoA-transferase family III domain SMALA_RS39630 40f523d8ce6bbee72eadaf30473752bf 412 Pfam PF02515 CoA-transferase family III 24 389 9.5E-117 T 29-03-2018 IPR003673 CoA-transferase family III GO:0003824 SMALA_RS39630 40f523d8ce6bbee72eadaf30473752bf 412 SUPERFAMILY SSF89796 22 412 1.03E-120 T 29-03-2018 IPR023606 CoA-transferase family III domain SMALA_RS30735 86e7bc5e3f32b8a9db7ca4fd8f40526a 185 Gene3D G3DSA:3.40.50.850 4 185 3.9E-45 T 29-03-2018 SMALA_RS30735 86e7bc5e3f32b8a9db7ca4fd8f40526a 185 Pfam PF00857 Isochorismatase family 10 173 2.6E-41 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SMALA_RS30735 86e7bc5e3f32b8a9db7ca4fd8f40526a 185 SUPERFAMILY SSF52499 8 184 7.72E-50 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SMALA_RS08785 ac52540d036a179a6d62cd5cfde234c2 345 Pfam PF13242 HAD-hyrolase-like 200 271 3.3E-15 T 29-03-2018 SMALA_RS08785 ac52540d036a179a6d62cd5cfde234c2 345 Gene3D G3DSA:3.40.50.1000 18 100 2.9E-5 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS08785 ac52540d036a179a6d62cd5cfde234c2 345 Pfam PF13344 Haloacid dehalogenase-like hydrolase 24 123 3.1E-24 T 29-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA SMALA_RS08785 ac52540d036a179a6d62cd5cfde234c2 345 SUPERFAMILY SSF56784 20 273 5.63E-52 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS08785 ac52540d036a179a6d62cd5cfde234c2 345 PIRSF PIRSF000915 2 278 9.9E-54 T 29-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA SMALA_RS08785 ac52540d036a179a6d62cd5cfde234c2 345 Gene3D G3DSA:3.40.50.1000 101 200 9.7E-23 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS36505 2ef0a69184be1c665eb2ad6d555a74b9 418 Pfam PF12876 Sugar-binding cellulase-like 13 117 4.3E-12 T 29-03-2018 IPR024778 Putative cellulase SMALA_RS36505 2ef0a69184be1c665eb2ad6d555a74b9 418 SUPERFAMILY SSF51445 14 241 2.43E-12 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS36505 2ef0a69184be1c665eb2ad6d555a74b9 418 SUPERFAMILY SSF51445 302 360 2.43E-12 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS36505 2ef0a69184be1c665eb2ad6d555a74b9 418 Gene3D G3DSA:3.20.20.80 13 400 5.3E-18 T 29-03-2018 SMALA_RS01635 164e21c180a7402ae3dfd63665c0ed80 513 Pfam PF13193 AMP-binding enzyme C-terminal domain 421 499 3.4E-19 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS01635 164e21c180a7402ae3dfd63665c0ed80 513 SUPERFAMILY SSF56801 3 510 5.36E-159 T 29-03-2018 SMALA_RS01635 164e21c180a7402ae3dfd63665c0ed80 513 Gene3D G3DSA:3.40.50.980 169 317 3.0E-50 T 29-03-2018 SMALA_RS01635 164e21c180a7402ae3dfd63665c0ed80 513 Pfam PF00501 AMP-binding enzyme 10 412 4.8E-111 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS01635 164e21c180a7402ae3dfd63665c0ed80 513 Gene3D G3DSA:2.30.38.10 318 405 9.5E-25 T 29-03-2018 SMALA_RS01635 164e21c180a7402ae3dfd63665c0ed80 513 Gene3D G3DSA:3.30.300.30 407 512 4.3E-29 T 29-03-2018 SMALA_RS01635 164e21c180a7402ae3dfd63665c0ed80 513 Gene3D G3DSA:3.40.50.980 1 168 4.8E-47 T 29-03-2018 SMALA_RS01635 164e21c180a7402ae3dfd63665c0ed80 513 ProSitePatterns PS00455 Putative AMP-binding domain signature. 163 174 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS13000 ea953ad025e7820cb0ede48cb7699d74 329 Gene3D G3DSA:1.20.272.10 211 329 2.5E-27 T 29-03-2018 SMALA_RS13000 ea953ad025e7820cb0ede48cb7699d74 329 Gene3D G3DSA:3.40.50.300 2 129 5.4E-12 T 29-03-2018 SMALA_RS13000 ea953ad025e7820cb0ede48cb7699d74 329 Gene3D G3DSA:1.10.8.60 135 210 5.5E-13 T 29-03-2018 SMALA_RS13000 ea953ad025e7820cb0ede48cb7699d74 329 SUPERFAMILY SSF52540 9 185 4.99E-6 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS13000 ea953ad025e7820cb0ede48cb7699d74 329 SUPERFAMILY SSF48019 203 322 2.38E-16 T 29-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 SMALA_RS13000 ea953ad025e7820cb0ede48cb7699d74 329 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 11 321 2.7E-33 T 29-03-2018 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 SMALA_RS13000 ea953ad025e7820cb0ede48cb7699d74 329 Pfam PF06144 DNA polymerase III, delta subunit 16 179 6.4E-11 T 29-03-2018 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 SMALA_RS14860 09feaa97f5d59c7a3efb32c59ee4e39d 649 SUPERFAMILY SSF50965 67 137 2.09E-37 T 29-03-2018 IPR011043 Galactose oxidase/kelch, beta-propeller SMALA_RS14860 09feaa97f5d59c7a3efb32c59ee4e39d 649 SUPERFAMILY SSF50965 258 544 2.09E-37 T 29-03-2018 IPR011043 Galactose oxidase/kelch, beta-propeller SMALA_RS14860 09feaa97f5d59c7a3efb32c59ee4e39d 649 SUPERFAMILY SSF81296 544 643 2.1E-21 T 29-03-2018 IPR014756 Immunoglobulin E-set SMALA_RS14860 09feaa97f5d59c7a3efb32c59ee4e39d 649 Gene3D G3DSA:2.130.10.80 48 549 2.3E-72 T 29-03-2018 IPR015916 Galactose oxidase, beta-propeller SMALA_RS14860 09feaa97f5d59c7a3efb32c59ee4e39d 649 Gene3D G3DSA:2.60.40.10 550 644 2.1E-24 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS14860 09feaa97f5d59c7a3efb32c59ee4e39d 649 Pfam PF09118 Domain of unknown function (DUF1929) 548 643 1.6E-22 T 29-03-2018 IPR015202 Galactose oxidase-like, Early set domain SMALA_RS12580 6f73f8467c40d2864667d782eb9ded1d 381 SUPERFAMILY SSF53383 6 378 1.15E-56 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS12580 6f73f8467c40d2864667d782eb9ded1d 381 Gene3D G3DSA:3.40.640.10 22 259 1.0E-31 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS12580 6f73f8467c40d2864667d782eb9ded1d 381 Pfam PF00266 Aminotransferase class-V 57 371 1.8E-23 T 29-03-2018 IPR000192 Aminotransferase class V domain SMALA_RS12580 6f73f8467c40d2864667d782eb9ded1d 381 Gene3D G3DSA:3.90.1150.10 260 381 2.2E-9 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS40550 3655c6023f47eaad54523345303b7bc0 549 SUPERFAMILY SSF55920 305 548 1.3E-13 T 29-03-2018 IPR000994 Peptidase M24 SMALA_RS40550 3655c6023f47eaad54523345303b7bc0 549 Gene3D G3DSA:3.40.350.10 179 299 4.1E-5 T 29-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal SMALA_RS40550 3655c6023f47eaad54523345303b7bc0 549 Gene3D G3DSA:3.90.230.10 301 527 9.0E-10 T 29-03-2018 SMALA_RS40550 3655c6023f47eaad54523345303b7bc0 549 Pfam PF00557 Metallopeptidase family M24 313 495 4.5E-7 T 29-03-2018 IPR000994 Peptidase M24 SMALA_RS02685 bc69dbee0a5a74b9a12fea698c9d9bfb 317 Gene3D G3DSA:3.90.180.10 225 317 8.1E-8 T 29-03-2018 SMALA_RS02685 bc69dbee0a5a74b9a12fea698c9d9bfb 317 SUPERFAMILY SSF51735 118 240 4.45E-33 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS02685 bc69dbee0a5a74b9a12fea698c9d9bfb 317 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 146 167 - T 29-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 SMALA_RS02685 bc69dbee0a5a74b9a12fea698c9d9bfb 317 SMART SM00829 10 313 1.9E-23 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS02685 bc69dbee0a5a74b9a12fea698c9d9bfb 317 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 94 1.9E-9 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS02685 bc69dbee0a5a74b9a12fea698c9d9bfb 317 Gene3D G3DSA:3.40.50.20 164 224 3.4E-5 T 29-03-2018 SMALA_RS02685 bc69dbee0a5a74b9a12fea698c9d9bfb 317 SUPERFAMILY SSF50129 1 150 1.51E-39 T 29-03-2018 IPR011032 GroES-like SMALA_RS02685 bc69dbee0a5a74b9a12fea698c9d9bfb 317 Pfam PF13602 Zinc-binding dehydrogenase 188 313 2.8E-24 T 29-03-2018 SMALA_RS02685 bc69dbee0a5a74b9a12fea698c9d9bfb 317 Gene3D G3DSA:3.90.180.10 1 163 2.5E-56 T 29-03-2018 SMALA_RS27590 56f414f952b44608ad15add13333ea76 389 Gene3D G3DSA:3.40.640.10 13 260 2.2E-48 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS27590 56f414f952b44608ad15add13333ea76 389 SUPERFAMILY SSF53383 1 381 1.33E-93 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS27590 56f414f952b44608ad15add13333ea76 389 Pfam PF00266 Aminotransferase class-V 2 372 4.9E-61 T 29-03-2018 IPR000192 Aminotransferase class V domain SMALA_RS27590 56f414f952b44608ad15add13333ea76 389 PIRSF PIRSF005572 1 386 1.5E-107 T 29-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 SMALA_RS27590 56f414f952b44608ad15add13333ea76 389 Gene3D G3DSA:3.90.1150.10 268 386 2.7E-34 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS11820 8558319afad7e63769eb701408b11b00 274 SUPERFAMILY SSF51735 26 272 2.18E-78 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS11820 8558319afad7e63769eb701408b11b00 274 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 33 271 1.5E-63 T 29-03-2018 SMALA_RS11820 8558319afad7e63769eb701408b11b00 274 Gene3D G3DSA:3.40.50.720 22 62 2.4E-10 T 29-03-2018 SMALA_RS11820 8558319afad7e63769eb701408b11b00 274 Gene3D G3DSA:3.40.50.720 63 274 1.1E-61 T 29-03-2018 SMALA_RS11820 8558319afad7e63769eb701408b11b00 274 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 27 199 0.0035 T 29-03-2018 SMALA_RS11820 8558319afad7e63769eb701408b11b00 274 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 178 197 4.0E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS11820 8558319afad7e63769eb701408b11b00 274 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 102 113 4.0E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS11820 8558319afad7e63769eb701408b11b00 274 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 166 4.0E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS11820 8558319afad7e63769eb701408b11b00 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 102 113 2.2E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS11820 8558319afad7e63769eb701408b11b00 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 28 45 2.2E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS11820 8558319afad7e63769eb701408b11b00 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 197 2.2E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS11820 8558319afad7e63769eb701408b11b00 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 168 2.2E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS11820 8558319afad7e63769eb701408b11b00 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 199 216 2.2E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS11820 8558319afad7e63769eb701408b11b00 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 235 255 2.2E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS35135 a8048c635e2330c02e4d9f1bf323a30e 651 Pfam PF10022 Uncharacterized protein conserved in bacteria (DUF2264) 22 371 3.8E-102 T 29-03-2018 IPR016624 Uncharacterised conserved protein UCP014753 SMALA_RS11795 438d375def3965c51c3a0b2876b5b829 231 SUPERFAMILY SSF142695 50 201 4.05E-53 T 29-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 SMALA_RS11795 438d375def3965c51c3a0b2876b5b829 231 Pfam PF00925 GTP cyclohydrolase II 38 200 5.8E-58 T 29-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 SMALA_RS12230 1d761bb93274d63190db94bb111578e5 180 Gene3D G3DSA:1.10.150.120 81 179 1.4E-33 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 SMALA_RS12230 1d761bb93274d63190db94bb111578e5 180 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 12 62 1.3E-7 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SMALA_RS12230 1d761bb93274d63190db94bb111578e5 180 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 45 53 - T 29-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 SMALA_RS12230 1d761bb93274d63190db94bb111578e5 180 Pfam PF01799 [2Fe-2S] binding domain 79 169 4.8E-29 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 SMALA_RS12230 1d761bb93274d63190db94bb111578e5 180 Gene3D G3DSA:3.10.20.30 4 80 1.1E-26 T 29-03-2018 IPR012675 Beta-grasp domain SMALA_RS12230 1d761bb93274d63190db94bb111578e5 180 SUPERFAMILY SSF47741 90 176 8.77E-27 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 SMALA_RS12230 1d761bb93274d63190db94bb111578e5 180 SUPERFAMILY SSF54292 8 94 6.03E-27 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SMALA_RS27300 d6ead4b9dc4db96ba78b6da3c0e621f1 1027 Pfam PF03704 Bacterial transcriptional activator domain 100 251 2.8E-35 T 29-03-2018 IPR005158 Bacterial transcriptional activator domain SMALA_RS27300 d6ead4b9dc4db96ba78b6da3c0e621f1 1027 SMART SM00862 18 93 1.3E-11 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS27300 d6ead4b9dc4db96ba78b6da3c0e621f1 1027 Pfam PF00486 Transcriptional regulatory protein, C terminal 26 92 1.6E-9 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS27300 d6ead4b9dc4db96ba78b6da3c0e621f1 1027 SMART SM00028 974 1007 21.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS27300 d6ead4b9dc4db96ba78b6da3c0e621f1 1027 SMART SM00028 814 847 40.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS27300 d6ead4b9dc4db96ba78b6da3c0e621f1 1027 SMART SM00028 934 967 0.019 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS27300 d6ead4b9dc4db96ba78b6da3c0e621f1 1027 SMART SM00028 894 927 7.8E-4 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS27300 d6ead4b9dc4db96ba78b6da3c0e621f1 1027 SUPERFAMILY SSF52540 352 628 5.23E-26 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS27300 d6ead4b9dc4db96ba78b6da3c0e621f1 1027 SUPERFAMILY SSF48452 805 1005 8.22E-30 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS27300 d6ead4b9dc4db96ba78b6da3c0e621f1 1027 Pfam PF00931 NB-ARC domain 392 573 9.5E-14 T 29-03-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207 SMALA_RS27300 d6ead4b9dc4db96ba78b6da3c0e621f1 1027 Gene3D G3DSA:1.10.10.10 554 684 8.5E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS27300 d6ead4b9dc4db96ba78b6da3c0e621f1 1027 PRINTS PR00364 Disease resistance protein signature 559 573 1.7E-8 T 29-03-2018 SMALA_RS27300 d6ead4b9dc4db96ba78b6da3c0e621f1 1027 PRINTS PR00364 Disease resistance protein signature 392 407 1.7E-8 T 29-03-2018 SMALA_RS27300 d6ead4b9dc4db96ba78b6da3c0e621f1 1027 PRINTS PR00364 Disease resistance protein signature 471 485 1.7E-8 T 29-03-2018 SMALA_RS27300 d6ead4b9dc4db96ba78b6da3c0e621f1 1027 Gene3D G3DSA:1.25.40.10 955 1023 2.1E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS27300 d6ead4b9dc4db96ba78b6da3c0e621f1 1027 Gene3D G3DSA:1.25.40.10 905 954 2.8E-13 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS27300 d6ead4b9dc4db96ba78b6da3c0e621f1 1027 Gene3D G3DSA:3.30.70.100 785 859 6.8E-4 T 29-03-2018 SMALA_RS27300 d6ead4b9dc4db96ba78b6da3c0e621f1 1027 SMART SM01043 100 253 3.5E-40 T 29-03-2018 IPR005158 Bacterial transcriptional activator domain SMALA_RS27300 d6ead4b9dc4db96ba78b6da3c0e621f1 1027 Gene3D G3DSA:3.40.50.300 346 516 3.1E-15 T 29-03-2018 SMALA_RS27300 d6ead4b9dc4db96ba78b6da3c0e621f1 1027 Gene3D G3DSA:1.25.40.10 102 310 4.2E-20 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS27300 d6ead4b9dc4db96ba78b6da3c0e621f1 1027 Gene3D G3DSA:1.10.150.200 860 904 3.2E-7 T 29-03-2018 SMALA_RS27300 d6ead4b9dc4db96ba78b6da3c0e621f1 1027 SUPERFAMILY SSF48452 97 258 2.75E-28 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS27300 d6ead4b9dc4db96ba78b6da3c0e621f1 1027 Pfam PF13424 Tetratricopeptide repeat 866 925 3.6E-7 T 29-03-2018 SMALA_RS27300 d6ead4b9dc4db96ba78b6da3c0e621f1 1027 Pfam PF13424 Tetratricopeptide repeat 935 1004 5.3E-8 T 29-03-2018 SMALA_RS27300 d6ead4b9dc4db96ba78b6da3c0e621f1 1027 Gene3D G3DSA:1.10.10.10 11 101 1.1E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS27300 d6ead4b9dc4db96ba78b6da3c0e621f1 1027 SUPERFAMILY SSF46894 5 93 2.49E-12 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS38175 c2905dead3e1f898cef4889fdc25ba9b 211 Gene3D G3DSA:3.40.50.1000 79 202 7.2E-7 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS38175 c2905dead3e1f898cef4889fdc25ba9b 211 SUPERFAMILY SSF56784 77 195 2.54E-9 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS38175 c2905dead3e1f898cef4889fdc25ba9b 211 Pfam PF03767 HAD superfamily, subfamily IIIB (Acid phosphatase) 36 96 9.7E-8 T 29-03-2018 IPR005519 Acid phosphatase, class B-like SMALA_RS38175 c2905dead3e1f898cef4889fdc25ba9b 211 Pfam PF03767 HAD superfamily, subfamily IIIB (Acid phosphatase) 104 207 7.7E-17 T 29-03-2018 IPR005519 Acid phosphatase, class B-like SMALA_RS01140 12374f5f39b1a929f05948e88a37c475 575 SUPERFAMILY SSF48239 266 552 2.67E-43 T 29-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid SMALA_RS01140 12374f5f39b1a929f05948e88a37c475 575 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 244 261 3.1 T 29-03-2018 IPR001330 PFTB repeat GO:0003824 SMALA_RS01140 12374f5f39b1a929f05948e88a37c475 575 SUPERFAMILY SSF48239 43 303 1.44E-21 T 29-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid SMALA_RS01140 12374f5f39b1a929f05948e88a37c475 575 Gene3D G3DSA:1.50.10.20 378 564 1.8E-36 T 29-03-2018 SMALA_RS01140 12374f5f39b1a929f05948e88a37c475 575 Pfam PF13243 Squalene-hopene cyclase C-terminal domain 379 521 3.9E-16 T 29-03-2018 IPR032696 Squalene cyclase, C-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 SMALA_RS01140 12374f5f39b1a929f05948e88a37c475 575 Pfam PF13249 Squalene-hopene cyclase N-terminal domain 17 161 3.9E-8 T 29-03-2018 IPR032697 Squalene cyclase, N-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 SMALA_RS01140 12374f5f39b1a929f05948e88a37c475 575 Gene3D G3DSA:1.50.10.20 176 374 3.0E-16 T 29-03-2018 SMALA_RS01140 12374f5f39b1a929f05948e88a37c475 575 Gene3D G3DSA:1.50.10.20 36 175 1.3E-17 T 29-03-2018 SMALA_RS00845 d1435026d584b149d840ebbf309592f1 208 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 70 7.4E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS00845 d1435026d584b149d840ebbf309592f1 208 Gene3D G3DSA:1.10.357.10 77 199 4.9E-27 T 29-03-2018 SMALA_RS00845 d1435026d584b149d840ebbf309592f1 208 SUPERFAMILY SSF48498 89 194 2.54E-17 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS00845 d1435026d584b149d840ebbf309592f1 208 Pfam PF13305 WHG domain 97 174 1.4E-13 T 29-03-2018 IPR025996 WHG domain SMALA_RS00845 d1435026d584b149d840ebbf309592f1 208 Gene3D G3DSA:1.10.10.60 19 56 6.5E-16 T 29-03-2018 SMALA_RS00845 d1435026d584b149d840ebbf309592f1 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 24 37 2.4E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS00845 d1435026d584b149d840ebbf309592f1 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 68 2.4E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS00845 d1435026d584b149d840ebbf309592f1 208 SUPERFAMILY SSF46689 15 86 1.85E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS00845 d1435026d584b149d840ebbf309592f1 208 Gene3D G3DSA:1.10.10.60 57 76 1.9E-9 T 29-03-2018 SMALA_RS37560 26884073e35c6a59e73bf0af62af7226 301 Pfam PF13653 Glycerophosphoryl diester phosphodiesterase family 257 291 4.1E-8 T 29-03-2018 SMALA_RS37560 26884073e35c6a59e73bf0af62af7226 301 SUPERFAMILY SSF51695 56 182 1.94E-14 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 SMALA_RS37560 26884073e35c6a59e73bf0af62af7226 301 SUPERFAMILY SSF51695 221 293 1.94E-14 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 SMALA_RS37560 26884073e35c6a59e73bf0af62af7226 301 Gene3D G3DSA:3.20.20.190 51 298 2.6E-22 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 SMALA_RS19930 3ffb76d272f4fdab60b8817078d15dbc 316 Gene3D G3DSA:1.10.620.20 1 302 3.7E-85 T 29-03-2018 SMALA_RS19930 3ffb76d272f4fdab60b8817078d15dbc 316 SUPERFAMILY SSF47240 35 278 7.79E-85 T 29-03-2018 IPR009078 Ferritin-like superfamily SMALA_RS19930 3ffb76d272f4fdab60b8817078d15dbc 316 Pfam PF05138 Phenylacetic acid catabolic protein 25 299 2.3E-105 T 29-03-2018 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 SMALA_RS19930 3ffb76d272f4fdab60b8817078d15dbc 316 TIGRFAM TIGR02156 PA_CoA_Oxy1: phenylacetate-CoA oxygenase, PaaG subunit 15 303 1.5E-157 T 29-03-2018 IPR011881 1,2-phenylacetyl-CoA epoxidase, subunit A GO:0010124|GO:0097266 KEGG: 00360+1.14.13.14+1.14.13.149|KEGG: 00940+1.14.13.14|MetaCyc: PWY-5176 SMALA_RS19815 8689c59643b1d219696a0a22f2c1db5a 256 Pfam PF05949 Bacterial protein of unknown function (DUF881) 99 253 1.2E-41 T 29-03-2018 IPR010273 Protein of unknown function DUF881 SMALA_RS11310 deb5349dbc1727a9e2f6686f32462bc8 771 SUPERFAMILY SSF82866 131 331 2.49E-31 T 29-03-2018 SMALA_RS11310 deb5349dbc1727a9e2f6686f32462bc8 771 Gene3D G3DSA:1.20.1640.10 89 343 2.5E-35 T 29-03-2018 SMALA_RS11310 deb5349dbc1727a9e2f6686f32462bc8 771 Pfam PF03176 MMPL family 47 403 2.7E-71 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 SMALA_RS11310 deb5349dbc1727a9e2f6686f32462bc8 771 Pfam PF03176 MMPL family 433 732 5.2E-36 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 SMALA_RS11310 deb5349dbc1727a9e2f6686f32462bc8 771 Gene3D G3DSA:1.20.1640.10 510 730 2.6E-31 T 29-03-2018 SMALA_RS11310 deb5349dbc1727a9e2f6686f32462bc8 771 SUPERFAMILY SSF82866 534 731 1.05E-24 T 29-03-2018 SMALA_RS38700 6ebe61c1b0a7e91b838bb93d784f701e 532 Pfam PF01565 FAD binding domain 82 234 5.7E-23 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 SMALA_RS38700 6ebe61c1b0a7e91b838bb93d784f701e 532 Gene3D G3DSA:3.30.465.10 150 267 3.4E-30 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SMALA_RS38700 6ebe61c1b0a7e91b838bb93d784f701e 532 SUPERFAMILY SSF56176 70 263 1.64E-39 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SMALA_RS38700 6ebe61c1b0a7e91b838bb93d784f701e 532 Pfam PF08031 Berberine and berberine like 487 530 1.3E-16 T 29-03-2018 IPR012951 Berberine/berberine-like GO:0016491|GO:0050660|GO:0055114 SMALA_RS38700 6ebe61c1b0a7e91b838bb93d784f701e 532 Gene3D G3DSA:3.30.43.10 56 135 4.1E-14 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 SMALA_RS19905 aeabc348f1dc11dc59be8ef919cdaded 382 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 120 1.7E-16 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS19905 aeabc348f1dc11dc59be8ef919cdaded 382 SUPERFAMILY SSF56645 2 220 1.83E-34 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMALA_RS19905 aeabc348f1dc11dc59be8ef919cdaded 382 Gene3D G3DSA:1.20.140.10 233 357 1.7E-25 T 29-03-2018 SMALA_RS19905 aeabc348f1dc11dc59be8ef919cdaded 382 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 236 365 5.9E-19 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMALA_RS19905 aeabc348f1dc11dc59be8ef919cdaded 382 SUPERFAMILY SSF47203 234 375 8.54E-27 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMALA_RS19905 aeabc348f1dc11dc59be8ef919cdaded 382 Gene3D G3DSA:2.40.110.10 122 221 1.1E-13 T 29-03-2018 SMALA_RS19905 aeabc348f1dc11dc59be8ef919cdaded 382 Gene3D G3DSA:1.10.540.10 1 121 4.5E-22 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS42605 7282714f31a91eb35aa963cf7f1bd200 211 SUPERFAMILY SSF56784 6 193 1.46E-27 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS42605 7282714f31a91eb35aa963cf7f1bd200 211 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 124 184 1.4E-9 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMALA_RS42605 7282714f31a91eb35aa963cf7f1bd200 211 Pfam PF13419 Haloacid dehalogenase-like hydrolase 101 184 4.1E-5 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS42605 7282714f31a91eb35aa963cf7f1bd200 211 Gene3D G3DSA:3.40.50.1000 3 207 6.5E-17 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS05440 b1658a12b59667024b98ecdb27065860 267 SUPERFAMILY SSF56281 11 257 2.35E-15 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS05440 b1658a12b59667024b98ecdb27065860 267 Gene3D G3DSA:3.60.15.10 1 263 3.0E-21 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS05440 b1658a12b59667024b98ecdb27065860 267 Pfam PF12706 Beta-lactamase superfamily domain 29 235 1.1E-14 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS41510 7ecec4d8b3c2ed7dabfcf22b954a6bbf 182 Pfam PF13302 Acetyltransferase (GNAT) domain 18 158 5.2E-24 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SMALA_RS41510 7ecec4d8b3c2ed7dabfcf22b954a6bbf 182 SUPERFAMILY SSF55729 12 163 1.98E-30 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS41510 7ecec4d8b3c2ed7dabfcf22b954a6bbf 182 Gene3D G3DSA:3.40.630.30 1 179 1.4E-30 T 29-03-2018 SMALA_RS38720 6dfaca0796c148610011d99b6315c156 301 Gene3D G3DSA:1.10.260.40 8 79 8.2E-10 T 29-03-2018 SMALA_RS38720 6dfaca0796c148610011d99b6315c156 301 Pfam PF10901 Protein of unknown function (DUF2690) 190 283 2.8E-13 T 29-03-2018 IPR021224 Protein of unknown function DUF2690 SMALA_RS38720 6dfaca0796c148610011d99b6315c156 301 SUPERFAMILY SSF47413 15 78 1.13E-7 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS38720 6dfaca0796c148610011d99b6315c156 301 Pfam PF13560 Helix-turn-helix domain 16 71 5.8E-10 T 29-03-2018 SMALA_RS15575 fe5354c554c04ff9459969d25acc6f45 293 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 105 277 5.1E-15 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS15575 fe5354c554c04ff9459969d25acc6f45 293 Gene3D G3DSA:1.10.3720.10 15 281 4.2E-40 T 29-03-2018 SMALA_RS15575 fe5354c554c04ff9459969d25acc6f45 293 SUPERFAMILY SSF161098 26 293 3.01E-63 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS32975 340a3e428cd46a30e2f8f59416e503d1 431 Gene3D G3DSA:3.30.565.10 279 416 6.9E-24 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS32975 340a3e428cd46a30e2f8f59416e503d1 431 PIRSF PIRSF037434 23 417 1.7E-76 T 29-03-2018 IPR017205 Signal transduction histidine kinase, ChrS SMALA_RS32975 340a3e428cd46a30e2f8f59416e503d1 431 SUPERFAMILY SSF55874 286 410 1.23E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS32975 340a3e428cd46a30e2f8f59416e503d1 431 Pfam PF07730 Histidine kinase 215 281 3.3E-14 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMALA_RS32975 340a3e428cd46a30e2f8f59416e503d1 431 SMART SM00387 320 413 1.8E-9 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS15990 07e4e2377124b210283e23f678d9701a 508 Pfam PF00854 POT family 106 466 1.3E-59 T 29-03-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-427975 SMALA_RS15990 07e4e2377124b210283e23f678d9701a 508 Gene3D G3DSA:1.20.1250.20 11 222 7.1E-20 T 29-03-2018 SMALA_RS15990 07e4e2377124b210283e23f678d9701a 508 Gene3D G3DSA:1.20.1250.20 295 502 1.1E-11 T 29-03-2018 SMALA_RS15990 07e4e2377124b210283e23f678d9701a 508 SUPERFAMILY SSF103473 21 223 5.49E-26 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS15990 07e4e2377124b210283e23f678d9701a 508 SUPERFAMILY SSF103473 295 497 5.49E-26 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS15990 07e4e2377124b210283e23f678d9701a 508 ProSitePatterns PS01023 PTR2 family proton/oligopeptide symporters signature 2. 168 180 - T 29-03-2018 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 SMALA_RS15990 07e4e2377124b210283e23f678d9701a 508 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 17 504 2.6E-183 T 29-03-2018 IPR005279 Dipeptide/tripeptide permease GO:0015197|GO:0015833|GO:0016020 SMALA_RS25970 35620a2856de10965082e5635cf7435c 392 Pfam PF00899 ThiF family 21 254 2.1E-67 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 SMALA_RS25970 35620a2856de10965082e5635cf7435c 392 Pfam PF00581 Rhodanese-like domain 290 383 1.0E-13 T 29-03-2018 IPR001763 Rhodanese-like domain SMALA_RS25970 35620a2856de10965082e5635cf7435c 392 SMART SM00450 290 387 6.2E-24 T 29-03-2018 IPR001763 Rhodanese-like domain SMALA_RS25970 35620a2856de10965082e5635cf7435c 392 Gene3D G3DSA:3.40.250.10 266 389 8.7E-25 T 29-03-2018 IPR001763 Rhodanese-like domain SMALA_RS25970 35620a2856de10965082e5635cf7435c 392 Gene3D G3DSA:3.40.50.720 10 259 2.9E-78 T 29-03-2018 SMALA_RS25970 35620a2856de10965082e5635cf7435c 392 SUPERFAMILY SSF69572 7 357 1.96E-107 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 SMALA_RS31285 45b3f930349312001fa7836b9d72f3a5 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 1.1E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS31285 45b3f930349312001fa7836b9d72f3a5 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 1.1E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS31285 45b3f930349312001fa7836b9d72f3a5 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 1.1E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS31285 45b3f930349312001fa7836b9d72f3a5 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 3.1E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS31285 45b3f930349312001fa7836b9d72f3a5 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 3.1E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS31285 45b3f930349312001fa7836b9d72f3a5 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 3.1E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS31285 45b3f930349312001fa7836b9d72f3a5 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 3.1E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS31285 45b3f930349312001fa7836b9d72f3a5 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 3.1E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS31285 45b3f930349312001fa7836b9d72f3a5 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 3.1E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS31285 45b3f930349312001fa7836b9d72f3a5 252 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMALA_RS31285 45b3f930349312001fa7836b9d72f3a5 252 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 250 2.6E-60 T 29-03-2018 SMALA_RS31285 45b3f930349312001fa7836b9d72f3a5 252 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 188 0.0015 T 29-03-2018 SMALA_RS31285 45b3f930349312001fa7836b9d72f3a5 252 SUPERFAMILY SSF51735 6 251 1.19E-74 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS31285 45b3f930349312001fa7836b9d72f3a5 252 Gene3D G3DSA:3.40.50.720 43 252 3.3E-57 T 29-03-2018 SMALA_RS31285 45b3f930349312001fa7836b9d72f3a5 252 Gene3D G3DSA:3.40.50.720 1 42 1.1E-10 T 29-03-2018 SMALA_RS01255 a41045a5095b06ec15c4bc4f65ba2f56 445 PIRSF PIRSF002746 1 441 7.2E-136 T 29-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 SMALA_RS01255 a41045a5095b06ec15c4bc4f65ba2f56 445 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 1 437 3.3E-142 T 29-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 SMALA_RS01255 a41045a5095b06ec15c4bc4f65ba2f56 445 Pfam PF02447 GntP family permease 1 436 8.1E-139 T 29-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 SMALA_RS08770 bf3e949e0f4de1f8e164798d563943b2 274 SUPERFAMILY SSF52540 3 225 6.01E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS08770 bf3e949e0f4de1f8e164798d563943b2 274 SMART SM00382 24 213 5.0E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS08770 bf3e949e0f4de1f8e164798d563943b2 274 Pfam PF00005 ABC transporter 17 163 1.3E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS08770 bf3e949e0f4de1f8e164798d563943b2 274 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS08770 bf3e949e0f4de1f8e164798d563943b2 274 Gene3D G3DSA:3.40.50.300 1 231 5.8E-57 T 29-03-2018 SMALA_RS01690 010fed7e5cb2eff1c2adb7b90651429c 534 Pfam PF13556 PucR C-terminal helix-turn-helix domain 463 519 2.4E-12 T 29-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain SMALA_RS01690 010fed7e5cb2eff1c2adb7b90651429c 534 Pfam PF07905 Purine catabolism regulatory protein-like family 8 129 1.6E-36 T 29-03-2018 IPR012914 Purine catabolism PurC-like domain SMALA_RS07940 6661458fe5ecc51d2f69a8bd003b3a24 700 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 87 354 1.9E-31 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMALA_RS07940 6661458fe5ecc51d2f69a8bd003b3a24 700 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 389 616 3.3E-41 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMALA_RS07940 6661458fe5ecc51d2f69a8bd003b3a24 700 Gene3D G3DSA:3.40.50.1000 461 589 2.1E-34 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS07940 6661458fe5ecc51d2f69a8bd003b3a24 700 Pfam PF00702 haloacid dehalogenase-like hydrolase 314 547 1.7E-31 T 29-03-2018 SMALA_RS07940 6661458fe5ecc51d2f69a8bd003b3a24 700 SUPERFAMILY SSF81665 53 118 9.68E-12 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SMALA_RS07940 6661458fe5ecc51d2f69a8bd003b3a24 700 SUPERFAMILY SSF81665 220 311 9.68E-12 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SMALA_RS07940 6661458fe5ecc51d2f69a8bd003b3a24 700 SUPERFAMILY SSF56784 408 583 2.34E-39 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS07940 6661458fe5ecc51d2f69a8bd003b3a24 700 SUPERFAMILY SSF56784 316 335 2.34E-39 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS07940 6661458fe5ecc51d2f69a8bd003b3a24 700 Gene3D G3DSA:3.40.1110.10 328 460 7.1E-20 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 SMALA_RS07940 6661458fe5ecc51d2f69a8bd003b3a24 700 Hamap MF_00285 Potassium-transporting ATPase ATP-binding subunit [kdpB]. 29 697 40.821 T 29-03-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 SMALA_RS07940 6661458fe5ecc51d2f69a8bd003b3a24 700 TIGRFAM TIGR01497 kdpB: K+-transporting ATPase, B subunit 28 693 0.0 T 29-03-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 SMALA_RS07940 6661458fe5ecc51d2f69a8bd003b3a24 700 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 319 325 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 SMALA_RS07940 6661458fe5ecc51d2f69a8bd003b3a24 700 Gene3D G3DSA:2.70.150.10 15 220 1.5E-27 T 29-03-2018 SMALA_RS07940 6661458fe5ecc51d2f69a8bd003b3a24 700 SUPERFAMILY SSF81653 121 219 5.23E-22 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 SMALA_RS07940 6661458fe5ecc51d2f69a8bd003b3a24 700 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 166 180 3.3E-25 T 29-03-2018 SMALA_RS07940 6661458fe5ecc51d2f69a8bd003b3a24 700 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 556 568 3.3E-25 T 29-03-2018 SMALA_RS07940 6661458fe5ecc51d2f69a8bd003b3a24 700 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 533 552 3.3E-25 T 29-03-2018 SMALA_RS07940 6661458fe5ecc51d2f69a8bd003b3a24 700 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 317 331 3.3E-25 T 29-03-2018 SMALA_RS07940 6661458fe5ecc51d2f69a8bd003b3a24 700 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 480 490 3.3E-25 T 29-03-2018 SMALA_RS07940 6661458fe5ecc51d2f69a8bd003b3a24 700 Pfam PF00122 E1-E2 ATPase 120 295 7.0E-36 T 29-03-2018 SMALA_RS03275 337c12f03db78cffcb493f3344dd4f3f 173 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 30 55 3.5E-4 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 SMALA_RS03275 337c12f03db78cffcb493f3344dd4f3f 173 Gene3D G3DSA:1.10.1780.10 17 172 8.7E-24 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 SMALA_RS16380 2b4906ea69ed0feecf2cd75f86b6453d 482 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 363 468 5.2E-24 T 29-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 SMALA_RS16380 2b4906ea69ed0feecf2cd75f86b6453d 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 5.2E-53 T 29-03-2018 SMALA_RS16380 2b4906ea69ed0feecf2cd75f86b6453d 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 193 218 5.2E-53 T 29-03-2018 SMALA_RS16380 2b4906ea69ed0feecf2cd75f86b6453d 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 321 328 5.2E-53 T 29-03-2018 SMALA_RS16380 2b4906ea69ed0feecf2cd75f86b6453d 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 157 166 5.2E-53 T 29-03-2018 SMALA_RS16380 2b4906ea69ed0feecf2cd75f86b6453d 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 278 292 5.2E-53 T 29-03-2018 SMALA_RS16380 2b4906ea69ed0feecf2cd75f86b6453d 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 422 437 5.2E-53 T 29-03-2018 SMALA_RS16380 2b4906ea69ed0feecf2cd75f86b6453d 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 5.2E-53 T 29-03-2018 SMALA_RS16380 2b4906ea69ed0feecf2cd75f86b6453d 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 357 378 5.2E-53 T 29-03-2018 SMALA_RS16380 2b4906ea69ed0feecf2cd75f86b6453d 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 444 464 5.2E-53 T 29-03-2018 SMALA_RS16380 2b4906ea69ed0feecf2cd75f86b6453d 482 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 3.5E-34 T 29-03-2018 SMALA_RS16380 2b4906ea69ed0feecf2cd75f86b6453d 482 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 193 211 3.5E-34 T 29-03-2018 SMALA_RS16380 2b4906ea69ed0feecf2cd75f86b6453d 482 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 277 293 3.5E-34 T 29-03-2018 SMALA_RS16380 2b4906ea69ed0feecf2cd75f86b6453d 482 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 306 328 3.5E-34 T 29-03-2018 SMALA_RS16380 2b4906ea69ed0feecf2cd75f86b6453d 482 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 154 172 3.5E-34 T 29-03-2018 SMALA_RS16380 2b4906ea69ed0feecf2cd75f86b6453d 482 SUPERFAMILY SSF51905 3 350 8.87E-47 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS16380 2b4906ea69ed0feecf2cd75f86b6453d 482 SUPERFAMILY SSF55424 357 475 3.09E-29 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SMALA_RS16380 2b4906ea69ed0feecf2cd75f86b6453d 482 Gene3D G3DSA:3.40.50.720 179 349 6.8E-33 T 29-03-2018 SMALA_RS16380 2b4906ea69ed0feecf2cd75f86b6453d 482 PIRSF PIRSF000350 1 476 5.7E-77 T 29-03-2018 SMALA_RS16380 2b4906ea69ed0feecf2cd75f86b6453d 482 Gene3D G3DSA:3.50.50.60 1 178 6.2E-24 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS16380 2b4906ea69ed0feecf2cd75f86b6453d 482 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 341 2.7E-57 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS16380 2b4906ea69ed0feecf2cd75f86b6453d 482 Gene3D G3DSA:3.30.390.30 359 482 3.6E-29 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SMALA_RS20040 ea5df937d086716cfc197dee2192860c 388 Pfam PF00676 Dehydrogenase E1 component 65 346 1.2E-79 T 29-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 SMALA_RS20040 ea5df937d086716cfc197dee2192860c 388 Gene3D G3DSA:3.40.50.970 2 374 1.4E-92 T 29-03-2018 SMALA_RS20040 ea5df937d086716cfc197dee2192860c 388 TIGRFAM TIGR03181 PDH_E1_alph_x: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 35 373 3.7E-138 T 29-03-2018 IPR017596 Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 SMALA_RS20040 ea5df937d086716cfc197dee2192860c 388 SUPERFAMILY SSF52518 37 377 4.83E-99 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold SMALA_RS33305 875ede40964ebdbd40da026fdb5393d5 161 SUPERFAMILY SSF52121 11 155 5.89E-54 T 29-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 SMALA_RS33305 875ede40964ebdbd40da026fdb5393d5 161 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 12 156 28.505 T 29-03-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 SMALA_RS33305 875ede40964ebdbd40da026fdb5393d5 161 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 17 151 4.4E-42 T 29-03-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 SMALA_RS33305 875ede40964ebdbd40da026fdb5393d5 161 Gene3D G3DSA:3.40.50.960 2 158 6.4E-58 T 29-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 SMALA_RS33305 875ede40964ebdbd40da026fdb5393d5 161 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 17 152 1.5E-51 T 29-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 SMALA_RS16225 d9fcd4683a247ef161fc7d7261bd862f 417 PRINTS PR00359 B-class P450 signature 331 346 2.5E-55 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS16225 d9fcd4683a247ef161fc7d7261bd862f 417 PRINTS PR00359 B-class P450 signature 161 176 2.5E-55 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS16225 d9fcd4683a247ef161fc7d7261bd862f 417 PRINTS PR00359 B-class P450 signature 199 221 2.5E-55 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS16225 d9fcd4683a247ef161fc7d7261bd862f 417 PRINTS PR00359 B-class P450 signature 144 160 2.5E-55 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS16225 d9fcd4683a247ef161fc7d7261bd862f 417 PRINTS PR00359 B-class P450 signature 98 109 2.5E-55 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS16225 d9fcd4683a247ef161fc7d7261bd862f 417 PRINTS PR00359 B-class P450 signature 285 296 2.5E-55 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS16225 d9fcd4683a247ef161fc7d7261bd862f 417 PRINTS PR00359 B-class P450 signature 303 330 2.5E-55 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS16225 d9fcd4683a247ef161fc7d7261bd862f 417 PRINTS PR00359 B-class P450 signature 352 361 2.5E-55 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS16225 d9fcd4683a247ef161fc7d7261bd862f 417 PRINTS PR00359 B-class P450 signature 361 372 2.5E-55 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS16225 d9fcd4683a247ef161fc7d7261bd862f 417 Gene3D G3DSA:1.10.630.10 3 414 6.1E-83 T 29-03-2018 SMALA_RS16225 d9fcd4683a247ef161fc7d7261bd862f 417 Pfam PF00067 Cytochrome P450 191 381 4.8E-23 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS16225 d9fcd4683a247ef161fc7d7261bd862f 417 SUPERFAMILY SSF48264 14 412 3.27E-100 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS34505 00bbac199119054ca9ce29d52589c770 102 Pfam PF14542 GCN5-related N-acetyl-transferase 13 92 9.0E-25 T 29-03-2018 IPR031165 Yjdj-type Gcn5-related N-acetyltransferase SMALA_RS34505 00bbac199119054ca9ce29d52589c770 102 Gene3D G3DSA:3.40.630.30 1 102 7.7E-22 T 29-03-2018 SMALA_RS34505 00bbac199119054ca9ce29d52589c770 102 SUPERFAMILY SSF55729 3 94 3.6E-23 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS20765 f7163970012aab450f45f23ec65452bd 285 SUPERFAMILY SSF140959 29 284 2.62E-77 T 29-03-2018 SMALA_RS20765 f7163970012aab450f45f23ec65452bd 285 Pfam PF03301 Tryptophan 2,3-dioxygenase 16 285 2.5E-68 T 29-03-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 SMALA_RS20765 f7163970012aab450f45f23ec65452bd 285 Hamap MF_01972 Tryptophan 2,3-dioxygenase [kynA]. 23 285 35.897 T 29-03-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 SMALA_RS34030 9a0acfe56180c14069fe8438984c7b17 146 SUPERFAMILY SSF47413 46 84 2.31E-6 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS34030 9a0acfe56180c14069fe8438984c7b17 146 Pfam PF01381 Helix-turn-helix 27 81 2.0E-5 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS34030 9a0acfe56180c14069fe8438984c7b17 146 Gene3D G3DSA:1.10.260.40 5 98 4.9E-14 T 29-03-2018 SMALA_RS28045 8cc88a88494262076a0c203ec5f78686 68 Gene3D G3DSA:1.20.5.1000 17 64 5.2E-4 T 29-03-2018 SMALA_RS07255 0c0c6477be1d4836f57e25fc0192cf0c 72 Pfam PF05639 Pup-like protein 4 72 6.2E-31 T 29-03-2018 IPR008515 Ubiquitin-like, Pup SMALA_RS07255 0c0c6477be1d4836f57e25fc0192cf0c 72 Hamap MF_02106 Prokaryotic ubiquitin-like protein Pup [pup]. 1 72 17.753 T 29-03-2018 IPR008515 Ubiquitin-like, Pup SMALA_RS07255 0c0c6477be1d4836f57e25fc0192cf0c 72 TIGRFAM TIGR03687 pupylate_cterm: ubiquitin-like protein Pup 41 72 2.9E-21 T 29-03-2018 IPR008515 Ubiquitin-like, Pup SMALA_RS07255 0c0c6477be1d4836f57e25fc0192cf0c 72 Gene3D G3DSA:1.20.120.20 2 72 8.8E-4 T 29-03-2018 SMALA_RS43335 9d45749aacd1241a2bdbeda957752dec 184 SUPERFAMILY SSF55729 9 169 1.26E-14 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS43335 9d45749aacd1241a2bdbeda957752dec 184 Gene3D G3DSA:3.40.630.30 1 182 1.7E-15 T 29-03-2018 SMALA_RS03640 f24ba7fe501ff58b04cc3c006dee62ba 677 Gene3D G3DSA:1.10.530.10 50 246 1.1E-19 T 29-03-2018 SMALA_RS03640 f24ba7fe501ff58b04cc3c006dee62ba 677 Gene3D G3DSA:3.40.80.10 301 461 7.1E-34 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 SMALA_RS03640 f24ba7fe501ff58b04cc3c006dee62ba 677 SMART SM00644 301 441 5.1E-43 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 SMALA_RS03640 f24ba7fe501ff58b04cc3c006dee62ba 677 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 313 442 2.5E-25 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 SMALA_RS03640 f24ba7fe501ff58b04cc3c006dee62ba 677 SUPERFAMILY SSF55846 290 455 2.16E-38 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 SMALA_RS03640 f24ba7fe501ff58b04cc3c006dee62ba 677 SUPERFAMILY SSF53955 66 126 4.5E-6 T 29-03-2018 IPR023346 Lysozyme-like domain SMALA_RS34655 17c33923108b0c3ee5aca4ccadec198f 206 Gene3D G3DSA:3.90.870.10 1 206 1.6E-56 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain SMALA_RS34655 17c33923108b0c3ee5aca4ccadec198f 206 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 7 201 5.9E-53 T 29-03-2018 IPR006070 YrdC-like domain GO:0003725 SMALA_RS34655 17c33923108b0c3ee5aca4ccadec198f 206 Pfam PF01300 Telomere recombination 23 198 2.7E-42 T 29-03-2018 IPR006070 YrdC-like domain GO:0003725 SMALA_RS34655 17c33923108b0c3ee5aca4ccadec198f 206 SUPERFAMILY SSF55821 1 203 5.19E-58 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain SMALA_RS26915 188e3507395182a416276d7961f5a01c 304 PRINTS PR00126 ATP synthase gamma subunit signature 74 93 4.9E-30 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMALA_RS26915 188e3507395182a416276d7961f5a01c 304 PRINTS PR00126 ATP synthase gamma subunit signature 274 295 4.9E-30 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMALA_RS26915 188e3507395182a416276d7961f5a01c 304 PRINTS PR00126 ATP synthase gamma subunit signature 243 262 4.9E-30 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMALA_RS26915 188e3507395182a416276d7961f5a01c 304 PRINTS PR00126 ATP synthase gamma subunit signature 171 188 4.9E-30 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMALA_RS26915 188e3507395182a416276d7961f5a01c 304 Gene3D G3DSA:1.10.287.80 244 291 8.4E-12 T 29-03-2018 SMALA_RS26915 188e3507395182a416276d7961f5a01c 304 Hamap MF_00815 ATP synthase gamma chain [atpG]. 2 296 33.401 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMALA_RS26915 188e3507395182a416276d7961f5a01c 304 SUPERFAMILY SSF52943 3 296 3.01E-80 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMALA_RS26915 188e3507395182a416276d7961f5a01c 304 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 3 296 7.4E-93 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMALA_RS26915 188e3507395182a416276d7961f5a01c 304 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 282 295 - T 29-03-2018 IPR023632 ATP synthase, F1 complex, gamma subunit conserved site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMALA_RS26915 188e3507395182a416276d7961f5a01c 304 Gene3D G3DSA:3.40.1380.10 28 243 1.7E-69 T 29-03-2018 SMALA_RS26915 188e3507395182a416276d7961f5a01c 304 Pfam PF00231 ATP synthase 4 296 2.9E-88 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMALA_RS30895 88788226ee89511e2054fd8e70dbf89e 274 Gene3D G3DSA:1.10.357.10 91 224 9.4E-32 T 29-03-2018 SMALA_RS30895 88788226ee89511e2054fd8e70dbf89e 274 Gene3D G3DSA:1.10.10.60 3 90 3.5E-19 T 29-03-2018 SMALA_RS30895 88788226ee89511e2054fd8e70dbf89e 274 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 54 1.6E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS30895 88788226ee89511e2054fd8e70dbf89e 274 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 62 85 1.6E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS30895 88788226ee89511e2054fd8e70dbf89e 274 Pfam PF00440 Bacterial regulatory proteins, tetR family 43 82 1.2E-17 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS30895 88788226ee89511e2054fd8e70dbf89e 274 ProSitePatterns PS01081 TetR-type HTH domain signature. 53 84 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site SMALA_RS30895 88788226ee89511e2054fd8e70dbf89e 274 SUPERFAMILY SSF46689 30 99 2.17E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS27940 1706f2cf39f19f02415d6809bca91404 283 Hamap MF_02114 2-phospho-L-lactate guanylyltransferase [cofC]. 13 217 22.285 T 29-03-2018 IPR002835 2-phospho-L-lactate guanylyltransferase, CofC GO:0016779 KEGG: 00680+2.7.7.68|MetaCyc: PWY-5198 SMALA_RS27940 1706f2cf39f19f02415d6809bca91404 283 Pfam PF01983 Guanylyl transferase CofC like 15 216 1.6E-10 T 29-03-2018 IPR002835 2-phospho-L-lactate guanylyltransferase, CofC GO:0016779 KEGG: 00680+2.7.7.68|MetaCyc: PWY-5198 SMALA_RS27940 1706f2cf39f19f02415d6809bca91404 283 Gene3D G3DSA:3.90.550.10 11 191 1.8E-14 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS27940 1706f2cf39f19f02415d6809bca91404 283 TIGRFAM TIGR03552 F420_cofC: 2-phospho-L-lactate guanylyltransferase 15 210 3.1E-48 T 29-03-2018 IPR002835 2-phospho-L-lactate guanylyltransferase, CofC GO:0016779 KEGG: 00680+2.7.7.68|MetaCyc: PWY-5198 SMALA_RS27940 1706f2cf39f19f02415d6809bca91404 283 SUPERFAMILY SSF53448 14 217 4.02E-28 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS39350 4f5f7e8cd1c6b2adbed5f5b4543b2c18 182 Gene3D G3DSA:1.10.357.10 1 182 3.7E-31 T 29-03-2018 SMALA_RS39350 4f5f7e8cd1c6b2adbed5f5b4543b2c18 182 SUPERFAMILY SSF46689 2 72 7.48E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS39350 4f5f7e8cd1c6b2adbed5f5b4543b2c18 182 SUPERFAMILY SSF48498 77 159 2.3E-9 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS39350 4f5f7e8cd1c6b2adbed5f5b4543b2c18 182 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 57 6.4E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS39350 4f5f7e8cd1c6b2adbed5f5b4543b2c18 182 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 3.0E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS39350 4f5f7e8cd1c6b2adbed5f5b4543b2c18 182 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 3.0E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS27780 7959754329367080647286c35ac90b71 308 Pfam PF01619 Proline dehydrogenase 45 299 2.9E-31 T 29-03-2018 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|Reactome: R-HSA-70688 SMALA_RS27780 7959754329367080647286c35ac90b71 308 PIRSF PIRSF000196 1 308 4.4E-112 T 29-03-2018 IPR008219 Proline dehydrogenase, bacteria and archaea GO:0004657|GO:0010133 KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922 SMALA_RS27780 7959754329367080647286c35ac90b71 308 SUPERFAMILY SSF51730 35 302 5.1E-69 T 29-03-2018 IPR029041 FAD-linked oxidoreductase-like SMALA_RS27780 7959754329367080647286c35ac90b71 308 Gene3D G3DSA:3.20.20.220 4 307 1.3E-74 T 29-03-2018 IPR029041 FAD-linked oxidoreductase-like SMALA_RS31735 07138680ad44d5d595c9fdfe87aa4243 29 TIGRFAM TIGR02115 potass_kdpF: K+-transporting ATPase, F subunit 7 29 7.8E-9 T 29-03-2018 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 SMALA_RS31735 07138680ad44d5d595c9fdfe87aa4243 29 Pfam PF09604 F subunit of K+-transporting ATPase (Potass_KdpF) 7 29 7.7E-9 T 29-03-2018 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 SMALA_RS27165 ab602c36847b7c2769c76f090d1643a1 381 TIGRFAM TIGR00016 ackA: acetate kinase 42 378 3.7E-129 T 29-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 SMALA_RS27165 ab602c36847b7c2769c76f090d1643a1 381 Hamap MF_00020 Acetate kinase [ackA]. 1 381 166.775 T 29-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 SMALA_RS27165 ab602c36847b7c2769c76f090d1643a1 381 SUPERFAMILY SSF53067 5 180 5.76E-62 T 29-03-2018 SMALA_RS27165 ab602c36847b7c2769c76f090d1643a1 381 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 187 204 - T 29-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 SMALA_RS27165 ab602c36847b7c2769c76f090d1643a1 381 Gene3D G3DSA:3.30.420.40 180 381 1.3E-79 T 29-03-2018 SMALA_RS27165 ab602c36847b7c2769c76f090d1643a1 381 PIRSF PIRSF000722 3 381 9.0E-135 T 29-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 SMALA_RS27165 ab602c36847b7c2769c76f090d1643a1 381 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 6 17 - T 29-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 SMALA_RS27165 ab602c36847b7c2769c76f090d1643a1 381 Gene3D G3DSA:3.30.420.40 5 179 2.0E-69 T 29-03-2018 SMALA_RS27165 ab602c36847b7c2769c76f090d1643a1 381 Pfam PF00871 Acetokinase family 6 372 1.1E-140 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 SMALA_RS27165 ab602c36847b7c2769c76f090d1643a1 381 SUPERFAMILY SSF53067 141 378 8.95E-82 T 29-03-2018 SMALA_RS27165 ab602c36847b7c2769c76f090d1643a1 381 PRINTS PR00471 Acetate kinase family signature 305 321 4.4E-44 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 SMALA_RS27165 ab602c36847b7c2769c76f090d1643a1 381 PRINTS PR00471 Acetate kinase family signature 6 17 4.4E-44 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 SMALA_RS27165 ab602c36847b7c2769c76f090d1643a1 381 PRINTS PR00471 Acetate kinase family signature 157 170 4.4E-44 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 SMALA_RS27165 ab602c36847b7c2769c76f090d1643a1 381 PRINTS PR00471 Acetate kinase family signature 187 208 4.4E-44 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 SMALA_RS27165 ab602c36847b7c2769c76f090d1643a1 381 PRINTS PR00471 Acetate kinase family signature 360 372 4.4E-44 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 SMALA_RS27165 ab602c36847b7c2769c76f090d1643a1 381 PRINTS PR00471 Acetate kinase family signature 283 296 4.4E-44 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 SMALA_RS42565 2d1ca80785d0a2915f7b64ed8e5f09c9 296 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 286 9.7E-28 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS42565 2d1ca80785d0a2915f7b64ed8e5f09c9 296 SUPERFAMILY SSF161098 95 280 6.41E-26 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS42565 2d1ca80785d0a2915f7b64ed8e5f09c9 296 Gene3D G3DSA:1.10.3720.10 21 286 2.0E-41 T 29-03-2018 SMALA_RS18535 e5fb464374441a31a0377241a9bf6a62 903 Pfam PF13400 Putative Flp pilus-assembly TadE/G-like 8 54 8.1E-6 T 29-03-2018 IPR028087 Putative Flp pilus-assembly TadG-like, N-terminal SMALA_RS18535 e5fb464374441a31a0377241a9bf6a62 903 TIGRFAM TIGR03816 tadE_like_DECH: helicase/secretion neighborhood TadE-like protein 6 109 1.2E-25 T 29-03-2018 IPR021202 Apoptosis inhibitor Rv3654c-like SMALA_RS40450 5858738499c10d6e75f9e856a90f146e 225 Gene3D G3DSA:1.10.10.10 8 82 9.0E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS40450 5858738499c10d6e75f9e856a90f146e 225 Gene3D G3DSA:1.20.120.530 83 225 7.3E-34 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS40450 5858738499c10d6e75f9e856a90f146e 225 SUPERFAMILY SSF46785 14 84 1.2E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS40450 5858738499c10d6e75f9e856a90f146e 225 SMART SM00345 22 80 3.3E-10 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS40450 5858738499c10d6e75f9e856a90f146e 225 SMART SM00895 90 214 2.5E-15 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS40450 5858738499c10d6e75f9e856a90f146e 225 Pfam PF07729 FCD domain 91 212 1.4E-22 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS40450 5858738499c10d6e75f9e856a90f146e 225 Pfam PF00392 Bacterial regulatory proteins, gntR family 19 80 1.2E-13 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS40450 5858738499c10d6e75f9e856a90f146e 225 SUPERFAMILY SSF48008 86 219 5.75E-27 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS29170 0d9d90eb4cf46d4acaf2405b67213e1d 418 Gene3D G3DSA:1.20.1250.20 209 404 7.4E-21 T 29-03-2018 SMALA_RS29170 0d9d90eb4cf46d4acaf2405b67213e1d 418 SUPERFAMILY SSF103473 19 399 7.59E-34 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS29170 0d9d90eb4cf46d4acaf2405b67213e1d 418 Pfam PF07690 Major Facilitator Superfamily 223 402 2.4E-17 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS29170 0d9d90eb4cf46d4acaf2405b67213e1d 418 Gene3D G3DSA:1.20.1250.20 3 206 1.9E-10 T 29-03-2018 SMALA_RS04845 1f0781c8e815260c3d3f5e7107bdd143 614 SUPERFAMILY SSF52518 8 183 2.16E-32 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold SMALA_RS04845 1f0781c8e815260c3d3f5e7107bdd143 614 Gene3D G3DSA:3.40.50.970 379 609 3.8E-25 T 29-03-2018 SMALA_RS04845 1f0781c8e815260c3d3f5e7107bdd143 614 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 9 184 7.5E-35 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 SMALA_RS04845 1f0781c8e815260c3d3f5e7107bdd143 614 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 225 308 6.1E-9 T 29-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 SMALA_RS04845 1f0781c8e815260c3d3f5e7107bdd143 614 Gene3D G3DSA:3.40.50.970 2 202 5.5E-38 T 29-03-2018 SMALA_RS04845 1f0781c8e815260c3d3f5e7107bdd143 614 Gene3D G3DSA:3.40.50.1220 203 356 1.7E-16 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain SMALA_RS04845 1f0781c8e815260c3d3f5e7107bdd143 614 SUPERFAMILY SSF52467 223 346 3.93E-13 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain SMALA_RS04845 1f0781c8e815260c3d3f5e7107bdd143 614 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 441 581 3.6E-14 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 SMALA_RS04845 1f0781c8e815260c3d3f5e7107bdd143 614 SUPERFAMILY SSF52518 399 608 2.76E-28 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold SMALA_RS14600 2095f6d3084a149a532dfd683bc639b0 169 Pfam PF12903 Protein of unknown function (DUF3830) 11 168 2.4E-63 T 29-03-2018 IPR024532 Protein of unknown function DUF3830 SMALA_RS14600 2095f6d3084a149a532dfd683bc639b0 169 SUPERFAMILY SSF50891 11 154 9.1E-10 T 29-03-2018 IPR029000 Cyclophilin-like domain SMALA_RS09680 04ca850928f4465bb16d16f7aadf05d0 220 Pfam PF14273 Domain of unknown function (DUF4360) 36 215 4.7E-70 T 29-03-2018 IPR025649 Protein of unknown function DUF4360 SMALA_RS39370 98687b2606acf45c581976d995c6e505 364 Gene3D G3DSA:3.30.1780.10 1 150 7.4E-23 T 29-03-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 SMALA_RS39370 98687b2606acf45c581976d995c6e505 364 SUPERFAMILY SSF51735 278 355 4.2E-43 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS39370 98687b2606acf45c581976d995c6e505 364 SUPERFAMILY SSF51735 2 250 4.2E-43 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS39370 98687b2606acf45c581976d995c6e505 364 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 98 347 2.0E-29 T 29-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 SMALA_RS39370 98687b2606acf45c581976d995c6e505 364 Gene3D G3DSA:3.40.50.720 151 326 1.1E-16 T 29-03-2018 SMALA_RS31420 323edee26fb9337c83707f872ab085bd 463 Pfam PF07690 Major Facilitator Superfamily 48 356 7.3E-27 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS31420 323edee26fb9337c83707f872ab085bd 463 SUPERFAMILY SSF103473 29 446 8.24E-54 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS31420 323edee26fb9337c83707f872ab085bd 463 Gene3D G3DSA:1.20.1250.20 260 453 3.2E-24 T 29-03-2018 SMALA_RS31420 323edee26fb9337c83707f872ab085bd 463 Gene3D G3DSA:1.20.1250.20 30 229 4.2E-20 T 29-03-2018 SMALA_RS29050 fe285c2f78d3a7a24dd96d8b0773efbc 276 Gene3D G3DSA:2.40.10.10 74 142 7.9E-16 T 29-03-2018 SMALA_RS29050 fe285c2f78d3a7a24dd96d8b0773efbc 276 Pfam PF00089 Trypsin 36 271 7.2E-49 T 29-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 SMALA_RS29050 fe285c2f78d3a7a24dd96d8b0773efbc 276 Gene3D G3DSA:2.40.10.10 143 275 5.0E-35 T 29-03-2018 SMALA_RS29050 fe285c2f78d3a7a24dd96d8b0773efbc 276 SUPERFAMILY SSF50494 7 270 2.96E-58 T 29-03-2018 IPR009003 Peptidase S1, PA clan SMALA_RS29050 fe285c2f78d3a7a24dd96d8b0773efbc 276 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 227 238 - T 29-03-2018 IPR033116 Serine proteases, trypsin family, serine active site SMALA_RS29050 fe285c2f78d3a7a24dd96d8b0773efbc 276 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 79 84 - T 29-03-2018 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 SMALA_RS29050 fe285c2f78d3a7a24dd96d8b0773efbc 276 Gene3D G3DSA:2.40.10.10 36 73 2.7E-11 T 29-03-2018 SMALA_RS29050 fe285c2f78d3a7a24dd96d8b0773efbc 276 SMART SM00020 35 272 3.2E-60 T 29-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 SMALA_RS29050 fe285c2f78d3a7a24dd96d8b0773efbc 276 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 69 84 2.2E-11 T 29-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 SMALA_RS29050 fe285c2f78d3a7a24dd96d8b0773efbc 276 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 132 146 2.2E-11 T 29-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 SMALA_RS29050 fe285c2f78d3a7a24dd96d8b0773efbc 276 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 226 238 2.2E-11 T 29-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 SMALA_RS05080 0fb63f2c7ef86fe5f8e417d4be1fd7f8 194 SUPERFAMILY SSF46689 5 58 1.1E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS05080 0fb63f2c7ef86fe5f8e417d4be1fd7f8 194 Gene3D G3DSA:1.10.357.10 59 186 7.1E-16 T 29-03-2018 SMALA_RS05080 0fb63f2c7ef86fe5f8e417d4be1fd7f8 194 Gene3D G3DSA:1.10.10.60 6 58 1.4E-15 T 29-03-2018 SMALA_RS05080 0fb63f2c7ef86fe5f8e417d4be1fd7f8 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 55 9.8E-14 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS05080 0fb63f2c7ef86fe5f8e417d4be1fd7f8 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 2.3E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS05080 0fb63f2c7ef86fe5f8e417d4be1fd7f8 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 2.3E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS07010 98eeaf962c5e6c33705819492d4fbba9 537 Pfam PF13520 Amino acid permease 50 484 5.9E-41 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMALA_RS07010 98eeaf962c5e6c33705819492d4fbba9 537 PIRSF PIRSF006060 37 519 3.0E-60 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMALA_RS41810 bcb2fb5340a044f11b823a0e06c5b5d8 269 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 90 101 1.3E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS41810 bcb2fb5340a044f11b823a0e06c5b5d8 269 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 175 194 1.3E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS41810 bcb2fb5340a044f11b823a0e06c5b5d8 269 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 162 1.3E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS41810 bcb2fb5340a044f11b823a0e06c5b5d8 269 Gene3D G3DSA:3.40.50.720 56 269 4.3E-54 T 29-03-2018 SMALA_RS41810 bcb2fb5340a044f11b823a0e06c5b5d8 269 Gene3D G3DSA:3.40.50.720 10 55 1.0E-10 T 29-03-2018 SMALA_RS41810 bcb2fb5340a044f11b823a0e06c5b5d8 269 SUPERFAMILY SSF51735 17 267 1.5E-70 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS41810 bcb2fb5340a044f11b823a0e06c5b5d8 269 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 24 266 9.3E-55 T 29-03-2018 SMALA_RS41810 bcb2fb5340a044f11b823a0e06c5b5d8 269 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 162 190 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMALA_RS41810 bcb2fb5340a044f11b823a0e06c5b5d8 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 230 250 8.3E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS41810 bcb2fb5340a044f11b823a0e06c5b5d8 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 19 36 8.3E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS41810 bcb2fb5340a044f11b823a0e06c5b5d8 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 164 8.3E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS41810 bcb2fb5340a044f11b823a0e06c5b5d8 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 90 101 8.3E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS41810 bcb2fb5340a044f11b823a0e06c5b5d8 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 194 8.3E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS41810 bcb2fb5340a044f11b823a0e06c5b5d8 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 196 213 8.3E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS33715 467c5a5d6def3bb2ec9be4bda710153b 62 Gene3D G3DSA:1.10.720.10 26 62 1.3E-8 T 29-03-2018 SMALA_RS33715 467c5a5d6def3bb2ec9be4bda710153b 62 Pfam PF07498 Rho termination factor, N-terminal domain 33 59 1.1E-5 T 29-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 SMALA_RS03740 7286c241eeb6da6e80ce3da2dc5a5800 136 Gene3D G3DSA:3.10.180.10 2 136 1.1E-24 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS03740 7286c241eeb6da6e80ce3da2dc5a5800 136 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 132 6.3E-14 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMALA_RS03740 7286c241eeb6da6e80ce3da2dc5a5800 136 SUPERFAMILY SSF54593 2 132 1.15E-26 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS06545 b2b7b72c657d07fd8fd3015aac6dbd87 582 SMART SM00878 333 441 3.4E-55 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SMALA_RS06545 b2b7b72c657d07fd8fd3015aac6dbd87 582 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 537 554 - T 29-03-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SMALA_RS06545 b2b7b72c657d07fd8fd3015aac6dbd87 582 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 114 319 1.3E-75 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SMALA_RS06545 b2b7b72c657d07fd8fd3015aac6dbd87 582 Gene3D G3DSA:2.40.50.100 513 582 1.6E-18 T 29-03-2018 SMALA_RS06545 b2b7b72c657d07fd8fd3015aac6dbd87 582 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 109 3.2E-43 T 29-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SMALA_RS06545 b2b7b72c657d07fd8fd3015aac6dbd87 582 Gene3D G3DSA:3.30.1490.20 123 208 2.8E-17 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SMALA_RS06545 b2b7b72c657d07fd8fd3015aac6dbd87 582 Pfam PF02785 Biotin carboxylase C-terminal domain 333 441 5.0E-36 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SMALA_RS06545 b2b7b72c657d07fd8fd3015aac6dbd87 582 Gene3D G3DSA:3.40.50.20 1 122 3.4E-49 T 29-03-2018 SMALA_RS06545 b2b7b72c657d07fd8fd3015aac6dbd87 582 SUPERFAMILY SSF51246 328 444 1.36E-36 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 SMALA_RS06545 b2b7b72c657d07fd8fd3015aac6dbd87 582 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 285 292 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SMALA_RS06545 b2b7b72c657d07fd8fd3015aac6dbd87 582 SUPERFAMILY SSF52440 3 112 1.8E-45 T 29-03-2018 IPR016185 Pre-ATP-grasp domain SMALA_RS06545 b2b7b72c657d07fd8fd3015aac6dbd87 582 SUPERFAMILY SSF56059 114 321 5.48E-59 T 29-03-2018 SMALA_RS06545 b2b7b72c657d07fd8fd3015aac6dbd87 582 Gene3D G3DSA:3.30.470.20 209 444 4.9E-92 T 29-03-2018 SMALA_RS06545 b2b7b72c657d07fd8fd3015aac6dbd87 582 Pfam PF00364 Biotin-requiring enzyme 515 580 1.8E-17 T 29-03-2018 IPR000089 Biotin/lipoyl attachment SMALA_RS06545 b2b7b72c657d07fd8fd3015aac6dbd87 582 SUPERFAMILY SSF51230 509 580 6.94E-20 T 29-03-2018 IPR011053 Single hybrid motif SMALA_RS06950 4af6a23af0409e78a1e80b57153c0b4f 400 SMART SM00331 175 395 1.4E-16 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS06950 4af6a23af0409e78a1e80b57153c0b4f 400 Gene3D G3DSA:3.60.40.10 141 396 2.5E-24 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS06950 4af6a23af0409e78a1e80b57153c0b4f 400 SUPERFAMILY SSF81606 189 394 4.71E-10 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS06950 4af6a23af0409e78a1e80b57153c0b4f 400 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 203 395 9.8E-37 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS27755 e04140d4fc83e0219fa230eafd90df03 194 Pfam PF05685 Putative restriction endonuclease 20 181 2.4E-25 T 29-03-2018 IPR008538 Domain of unknown function DUF820 SMALA_RS27755 e04140d4fc83e0219fa230eafd90df03 194 SUPERFAMILY SSF52980 12 168 1.45E-20 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 SMALA_RS27755 e04140d4fc83e0219fa230eafd90df03 194 Gene3D G3DSA:3.90.1570.10 7 191 9.4E-30 T 29-03-2018 SMALA_RS10005 a0937100033c067990e102100995695c 210 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 13 88 6.0E-6 T 29-03-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 SMALA_RS10005 a0937100033c067990e102100995695c 210 TIGRFAM TIGR03085 TIGR03085: TIGR03085 family protein 5 203 4.0E-79 T 29-03-2018 IPR017519 Conserved hypothetical protein CHP03085 SMALA_RS10005 a0937100033c067990e102100995695c 210 SUPERFAMILY SSF109854 12 114 3.39E-8 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes SMALA_RS10005 a0937100033c067990e102100995695c 210 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 5 185 9.3E-40 T 29-03-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type SMALA_RS10005 a0937100033c067990e102100995695c 210 Gene3D G3DSA:1.20.120.450 1 174 7.2E-19 T 29-03-2018 SMALA_RS33345 81d43aed84d22ec47868bcae7143dc2b 476 Pfam PF13529 Peptidase_C39 like family 262 414 8.4E-28 T 29-03-2018 SMALA_RS33345 81d43aed84d22ec47868bcae7143dc2b 476 Gene3D G3DSA:3.90.70.10 283 468 7.8E-16 T 29-03-2018 SMALA_RS42680 686bea6d1501b8235d85e2d7480863fe 302 Gene3D G3DSA:3.40.50.1820 18 302 1.1E-50 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS42680 686bea6d1501b8235d85e2d7480863fe 302 PRINTS PR00111 Alpha/beta hydrolase fold signature 135 148 1.9E-18 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS42680 686bea6d1501b8235d85e2d7480863fe 302 PRINTS PR00111 Alpha/beta hydrolase fold signature 78 93 1.9E-18 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS42680 686bea6d1501b8235d85e2d7480863fe 302 PRINTS PR00111 Alpha/beta hydrolase fold signature 245 259 1.9E-18 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS42680 686bea6d1501b8235d85e2d7480863fe 302 PRINTS PR00111 Alpha/beta hydrolase fold signature 121 134 1.9E-18 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS42680 686bea6d1501b8235d85e2d7480863fe 302 Pfam PF12697 Alpha/beta hydrolase family 52 293 1.1E-17 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS42680 686bea6d1501b8235d85e2d7480863fe 302 PRINTS PR00412 Epoxide hydrolase signature 243 259 5.6E-8 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS42680 686bea6d1501b8235d85e2d7480863fe 302 PRINTS PR00412 Epoxide hydrolase signature 78 93 5.6E-8 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS42680 686bea6d1501b8235d85e2d7480863fe 302 PRINTS PR00412 Epoxide hydrolase signature 276 298 5.6E-8 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS42680 686bea6d1501b8235d85e2d7480863fe 302 PRINTS PR00412 Epoxide hydrolase signature 135 148 5.6E-8 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS42680 686bea6d1501b8235d85e2d7480863fe 302 SUPERFAMILY SSF53474 19 300 4.19E-60 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS08850 ed8c32052f67be0fe6119c747a1c3a5d 319 PRINTS PR00721 Stomatin signature 28 50 1.8E-31 T 29-03-2018 IPR001972 Stomatin family GO:0016020 SMALA_RS08850 ed8c32052f67be0fe6119c747a1c3a5d 319 PRINTS PR00721 Stomatin signature 76 97 1.8E-31 T 29-03-2018 IPR001972 Stomatin family GO:0016020 SMALA_RS08850 ed8c32052f67be0fe6119c747a1c3a5d 319 PRINTS PR00721 Stomatin signature 155 173 1.8E-31 T 29-03-2018 IPR001972 Stomatin family GO:0016020 SMALA_RS08850 ed8c32052f67be0fe6119c747a1c3a5d 319 PRINTS PR00721 Stomatin signature 131 154 1.8E-31 T 29-03-2018 IPR001972 Stomatin family GO:0016020 SMALA_RS08850 ed8c32052f67be0fe6119c747a1c3a5d 319 PRINTS PR00721 Stomatin signature 111 128 1.8E-31 T 29-03-2018 IPR001972 Stomatin family GO:0016020 SMALA_RS08850 ed8c32052f67be0fe6119c747a1c3a5d 319 PRINTS PR00721 Stomatin signature 174 195 1.8E-31 T 29-03-2018 IPR001972 Stomatin family GO:0016020 SMALA_RS08850 ed8c32052f67be0fe6119c747a1c3a5d 319 SMART SM00244 21 179 7.1E-53 T 29-03-2018 IPR001107 Band 7 domain SMALA_RS08850 ed8c32052f67be0fe6119c747a1c3a5d 319 SUPERFAMILY SSF117892 52 186 1.96E-39 T 29-03-2018 IPR001107 Band 7 domain SMALA_RS08850 ed8c32052f67be0fe6119c747a1c3a5d 319 Pfam PF01145 SPFH domain / Band 7 family 25 194 1.3E-35 T 29-03-2018 IPR001107 Band 7 domain SMALA_RS08850 ed8c32052f67be0fe6119c747a1c3a5d 319 ProSitePatterns PS01270 Band 7 protein family signature. 135 163 - T 29-03-2018 IPR018080 Band 7/stomatin-like, conserved site SMALA_RS17880 90358f6480e7f2174ab3344c5955fc35 751 PIRSF PIRSF015589 53 751 2.7E-281 T 29-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 SMALA_RS17880 90358f6480e7f2174ab3344c5955fc35 751 Gene3D G3DSA:3.30.870.10 377 561 1.5E-17 T 29-03-2018 SMALA_RS17880 90358f6480e7f2174ab3344c5955fc35 751 Pfam PF13090 Polyphosphate kinase C-terminal domain 391 739 6.7E-154 T 29-03-2018 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 SMALA_RS17880 90358f6480e7f2174ab3344c5955fc35 751 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 69 740 3.4E-250 T 29-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 SMALA_RS17880 90358f6480e7f2174ab3344c5955fc35 751 SUPERFAMILY SSF56024 562 744 3.81E-67 T 29-03-2018 SMALA_RS17880 90358f6480e7f2174ab3344c5955fc35 751 SUPERFAMILY SSF56024 387 558 7.22E-54 T 29-03-2018 SMALA_RS17880 90358f6480e7f2174ab3344c5955fc35 751 Gene3D G3DSA:3.30.870.10 562 750 4.9E-43 T 29-03-2018 SMALA_RS17880 90358f6480e7f2174ab3344c5955fc35 751 SUPERFAMILY SSF140356 67 171 1.44E-35 T 29-03-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 SMALA_RS17880 90358f6480e7f2174ab3344c5955fc35 751 Gene3D G3DSA:1.20.58.310 72 174 1.3E-36 T 29-03-2018 SMALA_RS17880 90358f6480e7f2174ab3344c5955fc35 751 SUPERFAMILY SSF143724 173 369 1.96E-64 T 29-03-2018 SMALA_RS17880 90358f6480e7f2174ab3344c5955fc35 751 Gene3D G3DSA:3.30.1840.10 175 363 7.5E-71 T 29-03-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 SMALA_RS17880 90358f6480e7f2174ab3344c5955fc35 751 Hamap MF_00347 Polyphosphate kinase [ppk]. 68 745 29.966 T 29-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 SMALA_RS17880 90358f6480e7f2174ab3344c5955fc35 751 Pfam PF13089 Polyphosphate kinase N-terminal domain 70 176 1.1E-36 T 29-03-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 SMALA_RS17880 90358f6480e7f2174ab3344c5955fc35 751 Pfam PF02503 Polyphosphate kinase middle domain 185 375 1.8E-65 T 29-03-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 SMALA_RS06520 70594afb10486732f759bfd82904d427 415 Pfam PF03055 Retinal pigment epithelial membrane protein 12 413 1.7E-99 T 29-03-2018 IPR004294 Carotenoid oxygenase GO:0016702|GO:0055114 SMALA_RS16275 75d54d7c5001dac9371c5bf0d5696941 205 Pfam PF13624 SurA N-terminal domain 33 149 6.3E-7 T 29-03-2018 SMALA_RS16275 75d54d7c5001dac9371c5bf0d5696941 205 Gene3D G3DSA:1.10.4030.10 28 156 1.9E-11 T 29-03-2018 SMALA_RS16275 75d54d7c5001dac9371c5bf0d5696941 205 SUPERFAMILY SSF109998 33 158 1.22E-10 T 29-03-2018 IPR027304 Trigger factor/SurA domain SMALA_RS26190 0330d338ced527c94da16a5131b6c257 105 Pfam PF13490 Putative zinc-finger 11 44 1.5E-8 T 29-03-2018 IPR027383 Putative zinc-finger SMALA_RS26190 0330d338ced527c94da16a5131b6c257 105 TIGRFAM TIGR02949 anti_SigH_actin: anti-sigma factor, TIGR02949 family 4 84 9.7E-36 T 29-03-2018 IPR014295 Anti-sigma factor SMALA_RS26190 0330d338ced527c94da16a5131b6c257 105 TIGRFAM TIGR03988 antisig_RsrA: mycothiol system anti-sigma-R factor 10 84 4.4E-30 T 29-03-2018 IPR024020 Anti sigma-R factor, mycothiol system,RsrA SMALA_RS04900 1153ff5d40e378a39ee79195799b79b2 535 Pfam PF01494 FAD binding domain 15 355 2.2E-63 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 SMALA_RS04900 1153ff5d40e378a39ee79195799b79b2 535 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 322 340 3.6E-35 T 29-03-2018 SMALA_RS04900 1153ff5d40e378a39ee79195799b79b2 535 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 16 38 3.6E-35 T 29-03-2018 SMALA_RS04900 1153ff5d40e378a39ee79195799b79b2 535 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 289 304 3.6E-35 T 29-03-2018 SMALA_RS04900 1153ff5d40e378a39ee79195799b79b2 535 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 166 181 3.6E-35 T 29-03-2018 SMALA_RS04900 1153ff5d40e378a39ee79195799b79b2 535 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 304 320 3.6E-35 T 29-03-2018 SMALA_RS04900 1153ff5d40e378a39ee79195799b79b2 535 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 340 356 3.6E-35 T 29-03-2018 SMALA_RS04900 1153ff5d40e378a39ee79195799b79b2 535 Gene3D G3DSA:3.50.50.60 6 401 2.2E-54 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS04900 1153ff5d40e378a39ee79195799b79b2 535 SUPERFAMILY SSF51905 276 386 4.92E-62 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS04900 1153ff5d40e378a39ee79195799b79b2 535 SUPERFAMILY SSF51905 15 187 4.92E-62 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS04395 3f91f7ef7be11860f6325c0f7c471cae 218 Pfam PF01596 O-methyltransferase 21 217 1.8E-65 T 29-03-2018 IPR002935 O-methyltransferase, family 3 GO:0008171 SMALA_RS04395 3f91f7ef7be11860f6325c0f7c471cae 218 SUPERFAMILY SSF53335 9 218 3.54E-44 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS04395 3f91f7ef7be11860f6325c0f7c471cae 218 Gene3D G3DSA:3.40.50.150 1 218 6.7E-39 T 29-03-2018 SMALA_RS32215 a021bb8c1657b7eb95d91a86839d0d27 411 SUPERFAMILY SSF56281 201 353 4.57E-35 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS32215 a021bb8c1657b7eb95d91a86839d0d27 411 SUPERFAMILY SSF56281 97 174 4.57E-35 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS32215 a021bb8c1657b7eb95d91a86839d0d27 411 Pfam PF12706 Beta-lactamase superfamily domain 114 315 1.2E-53 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS32215 a021bb8c1657b7eb95d91a86839d0d27 411 Gene3D G3DSA:3.60.15.10 64 355 6.9E-56 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS11320 714e2dac26f33a42be0142b6270e0a8c 244 Gene3D G3DSA:3.40.50.720 1 244 1.0E-61 T 29-03-2018 SMALA_RS11320 714e2dac26f33a42be0142b6270e0a8c 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 1.8E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS11320 714e2dac26f33a42be0142b6270e0a8c 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 1.8E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS11320 714e2dac26f33a42be0142b6270e0a8c 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 205 225 1.8E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS11320 714e2dac26f33a42be0142b6270e0a8c 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 1.8E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS11320 714e2dac26f33a42be0142b6270e0a8c 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.8E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS11320 714e2dac26f33a42be0142b6270e0a8c 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 1.8E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS11320 714e2dac26f33a42be0142b6270e0a8c 244 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 242 9.1E-51 T 29-03-2018 SMALA_RS11320 714e2dac26f33a42be0142b6270e0a8c 244 SUPERFAMILY SSF51735 5 243 2.63E-69 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS10690 f7a4319b96810aefd350561c2dd0f0d5 186 Gene3D G3DSA:3.40.630.30 108 177 9.1E-20 T 29-03-2018 SMALA_RS10690 f7a4319b96810aefd350561c2dd0f0d5 186 Pfam PF00583 Acetyltransferase (GNAT) family 53 158 2.3E-17 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SMALA_RS10690 f7a4319b96810aefd350561c2dd0f0d5 186 SUPERFAMILY SSF55729 25 183 3.88E-34 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS10690 f7a4319b96810aefd350561c2dd0f0d5 186 Gene3D G3DSA:3.40.630.30 20 107 4.8E-14 T 29-03-2018 SMALA_RS18915 bb96e13a5c9b1bc8bb2abe22eea52962 334 SUPERFAMILY SSF63829 58 313 5.49E-22 T 29-03-2018 SMALA_RS18915 bb96e13a5c9b1bc8bb2abe22eea52962 334 Gene3D G3DSA:2.120.10.30 8 169 2.9E-9 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like SMALA_RS18915 bb96e13a5c9b1bc8bb2abe22eea52962 334 Gene3D G3DSA:2.130.10.10 170 319 1.5E-7 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMALA_RS18100 6c777cc0d399438f78086a07c3b0a4a4 197 Gene3D G3DSA:3.30.70.560 28 188 1.5E-58 T 29-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 SMALA_RS18100 6c777cc0d399438f78086a07c3b0a4a4 197 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 118 129 - T 29-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 SMALA_RS18100 6c777cc0d399438f78086a07c3b0a4a4 197 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 32 163 9.3E-45 T 29-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 SMALA_RS18100 6c777cc0d399438f78086a07c3b0a4a4 197 SUPERFAMILY SSF55083 31 182 1.03E-49 T 29-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 SMALA_RS18100 6c777cc0d399438f78086a07c3b0a4a4 197 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 33 163 1.4E-37 T 29-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 SMALA_RS04415 acd0e585b8acf968abf99af776819f1e 400 Pfam PF00067 Cytochrome P450 271 370 1.2E-20 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS04415 acd0e585b8acf968abf99af776819f1e 400 Pfam PF00067 Cytochrome P450 207 266 1.1E-5 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS04415 acd0e585b8acf968abf99af776819f1e 400 PRINTS PR00385 P450 superfamily signature 273 284 1.6E-6 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS04415 acd0e585b8acf968abf99af776819f1e 400 PRINTS PR00385 P450 superfamily signature 238 255 1.6E-6 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS04415 acd0e585b8acf968abf99af776819f1e 400 PRINTS PR00385 P450 superfamily signature 340 349 1.6E-6 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS04415 acd0e585b8acf968abf99af776819f1e 400 PRINTS PR00385 P450 superfamily signature 349 360 1.6E-6 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS04415 acd0e585b8acf968abf99af776819f1e 400 SUPERFAMILY SSF48264 17 400 1.31E-91 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS04415 acd0e585b8acf968abf99af776819f1e 400 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 342 351 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMALA_RS04415 acd0e585b8acf968abf99af776819f1e 400 PRINTS PR00359 B-class P450 signature 192 214 4.3E-49 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS04415 acd0e585b8acf968abf99af776819f1e 400 PRINTS PR00359 B-class P450 signature 340 349 4.3E-49 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS04415 acd0e585b8acf968abf99af776819f1e 400 PRINTS PR00359 B-class P450 signature 138 154 4.3E-49 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS04415 acd0e585b8acf968abf99af776819f1e 400 PRINTS PR00359 B-class P450 signature 273 284 4.3E-49 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS04415 acd0e585b8acf968abf99af776819f1e 400 PRINTS PR00359 B-class P450 signature 155 170 4.3E-49 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS04415 acd0e585b8acf968abf99af776819f1e 400 PRINTS PR00359 B-class P450 signature 91 102 4.3E-49 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS04415 acd0e585b8acf968abf99af776819f1e 400 PRINTS PR00359 B-class P450 signature 291 318 4.3E-49 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS04415 acd0e585b8acf968abf99af776819f1e 400 PRINTS PR00359 B-class P450 signature 349 360 4.3E-49 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS04415 acd0e585b8acf968abf99af776819f1e 400 Gene3D G3DSA:1.10.630.10 7 400 6.8E-71 T 29-03-2018 SMALA_RS37920 9401b32d1780a19a97877cedda0d833b 478 Pfam PF13520 Amino acid permease 27 452 5.1E-26 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMALA_RS37920 9401b32d1780a19a97877cedda0d833b 478 PIRSF PIRSF006060 4 471 1.5E-53 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMALA_RS18450 44b2afd807931aa110792360cf8262f5 355 SUPERFAMILY SSF50022 6 114 1.3E-29 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMALA_RS18450 44b2afd807931aa110792360cf8262f5 355 Gene3D G3DSA:3.90.380.10 109 348 2.4E-39 T 29-03-2018 SMALA_RS18450 44b2afd807931aa110792360cf8262f5 355 Gene3D G3DSA:2.102.10.10 1 108 5.3E-22 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMALA_RS18450 44b2afd807931aa110792360cf8262f5 355 Pfam PF00355 Rieske [2Fe-2S] domain 9 91 2.0E-17 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMALA_RS18450 44b2afd807931aa110792360cf8262f5 355 SUPERFAMILY SSF55961 107 344 1.76E-36 T 29-03-2018 SMALA_RS00270 de7c4df47f013c7cb33515a1b21163ca 432 SUPERFAMILY SSF103473 47 423 1.7E-29 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS00270 de7c4df47f013c7cb33515a1b21163ca 432 Gene3D G3DSA:1.20.1250.20 302 431 6.1E-7 T 29-03-2018 SMALA_RS00270 de7c4df47f013c7cb33515a1b21163ca 432 ProSitePatterns PS00216 Sugar transport proteins signature 1. 92 108 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMALA_RS00270 de7c4df47f013c7cb33515a1b21163ca 432 Pfam PF07690 Major Facilitator Superfamily 48 316 1.9E-13 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS00270 de7c4df47f013c7cb33515a1b21163ca 432 Gene3D G3DSA:1.20.1250.20 38 219 4.9E-17 T 29-03-2018 SMALA_RS15385 29bdb11eb5418ed871d4f303a671c669 254 Pfam PF13490 Putative zinc-finger 11 40 1.1E-7 T 29-03-2018 IPR027383 Putative zinc-finger SMALA_RS41160 b6a70756b163f5abad371c015fb97239 254 SUPERFAMILY SSF53335 12 252 3.7E-27 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS41160 b6a70756b163f5abad371c015fb97239 254 Gene3D G3DSA:3.40.50.150 10 254 7.9E-29 T 29-03-2018 SMALA_RS41160 b6a70756b163f5abad371c015fb97239 254 Pfam PF13649 Methyltransferase domain 48 147 1.1E-12 T 29-03-2018 SMALA_RS05005 12f70e185d95662e7399c5ad42310553 429 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 187 215 - T 29-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 SMALA_RS05005 12f70e185d95662e7399c5ad42310553 429 Gene3D G3DSA:3.40.50.1970 18 197 2.0E-44 T 29-03-2018 SMALA_RS05005 12f70e185d95662e7399c5ad42310553 429 Gene3D G3DSA:1.20.1090.10 200 427 8.5E-54 T 29-03-2018 SMALA_RS05005 12f70e185d95662e7399c5ad42310553 429 SUPERFAMILY SSF56796 18 424 1.96E-98 T 29-03-2018 SMALA_RS05005 12f70e185d95662e7399c5ad42310553 429 Pfam PF00465 Iron-containing alcohol dehydrogenase 20 418 1.0E-104 T 29-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 SMALA_RS00200 22e1af9a5f3a2bb3bef4532deb42f57d 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 7.2E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS00200 22e1af9a5f3a2bb3bef4532deb42f57d 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 7.2E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS00200 22e1af9a5f3a2bb3bef4532deb42f57d 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 7.2E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS00200 22e1af9a5f3a2bb3bef4532deb42f57d 308 SUPERFAMILY SSF53850 94 300 9.24E-32 T 29-03-2018 SMALA_RS00200 22e1af9a5f3a2bb3bef4532deb42f57d 308 Gene3D G3DSA:1.10.10.10 1 88 1.6E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS00200 22e1af9a5f3a2bb3bef4532deb42f57d 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 66 6.0E-19 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS00200 22e1af9a5f3a2bb3bef4532deb42f57d 308 Gene3D G3DSA:3.40.190.10 189 274 1.8E-19 T 29-03-2018 SMALA_RS00200 22e1af9a5f3a2bb3bef4532deb42f57d 308 SUPERFAMILY SSF46785 7 114 7.75E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS00200 22e1af9a5f3a2bb3bef4532deb42f57d 308 Gene3D G3DSA:3.40.190.10 95 188 6.6E-23 T 29-03-2018 SMALA_RS00200 22e1af9a5f3a2bb3bef4532deb42f57d 308 Pfam PF03466 LysR substrate binding domain 93 297 4.8E-30 T 29-03-2018 IPR005119 LysR, substrate-binding SMALA_RS12425 cdfa175fc28fec33bdbaa43b091a297c 445 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 337 443 2.0E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS12425 cdfa175fc28fec33bdbaa43b091a297c 445 SUPERFAMILY SSF47384 214 296 1.43E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS12425 cdfa175fc28fec33bdbaa43b091a297c 445 PRINTS PR00344 Bacterial sensor protein C-terminal signature 429 442 1.1E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS12425 cdfa175fc28fec33bdbaa43b091a297c 445 PRINTS PR00344 Bacterial sensor protein C-terminal signature 370 384 1.1E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS12425 cdfa175fc28fec33bdbaa43b091a297c 445 PRINTS PR00344 Bacterial sensor protein C-terminal signature 405 423 1.1E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS12425 cdfa175fc28fec33bdbaa43b091a297c 445 PRINTS PR00344 Bacterial sensor protein C-terminal signature 388 398 1.1E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS12425 cdfa175fc28fec33bdbaa43b091a297c 445 SUPERFAMILY SSF55874 286 443 2.49E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS12425 cdfa175fc28fec33bdbaa43b091a297c 445 SMART SM00387 335 445 9.8E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS12425 cdfa175fc28fec33bdbaa43b091a297c 445 SMART SM00304 177 230 2.3E-7 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMALA_RS12425 cdfa175fc28fec33bdbaa43b091a297c 445 SMART SM00388 231 296 2.4E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS12425 cdfa175fc28fec33bdbaa43b091a297c 445 Gene3D G3DSA:1.10.287.130 218 284 5.3E-13 T 29-03-2018 SMALA_RS12425 cdfa175fc28fec33bdbaa43b091a297c 445 Gene3D G3DSA:3.30.565.10 285 445 4.0E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS12425 cdfa175fc28fec33bdbaa43b091a297c 445 Pfam PF00512 His Kinase A (phospho-acceptor) domain 232 295 1.4E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS12425 cdfa175fc28fec33bdbaa43b091a297c 445 SUPERFAMILY SSF158472 179 227 3.53E-6 T 29-03-2018 SMALA_RS33560 2b1fd573b228b5dbfaec4001faae3b68 417 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 110 368 5.0E-14 T 29-03-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 SMALA_RS33560 2b1fd573b228b5dbfaec4001faae3b68 417 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 21 272 3.7E-26 T 29-03-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 SMALA_RS33560 2b1fd573b228b5dbfaec4001faae3b68 417 SUPERFAMILY SSF50621 252 394 2.72E-30 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 SMALA_RS33560 2b1fd573b228b5dbfaec4001faae3b68 417 PRINTS PR01182 Ornithine decarboxylase signature 84 108 3.2E-9 T 29-03-2018 IPR002433 Ornithine decarboxylase GO:0006596 SMALA_RS33560 2b1fd573b228b5dbfaec4001faae3b68 417 PRINTS PR01182 Ornithine decarboxylase signature 355 368 3.2E-9 T 29-03-2018 IPR002433 Ornithine decarboxylase GO:0006596 SMALA_RS33560 2b1fd573b228b5dbfaec4001faae3b68 417 PRINTS PR01182 Ornithine decarboxylase signature 40 67 3.2E-9 T 29-03-2018 IPR002433 Ornithine decarboxylase GO:0006596 SMALA_RS33560 2b1fd573b228b5dbfaec4001faae3b68 417 PRINTS PR01182 Ornithine decarboxylase signature 335 345 3.2E-9 T 29-03-2018 IPR002433 Ornithine decarboxylase GO:0006596 SMALA_RS33560 2b1fd573b228b5dbfaec4001faae3b68 417 SUPERFAMILY SSF51419 20 275 8.67E-49 T 29-03-2018 IPR029066 PLP-binding barrel SMALA_RS33560 2b1fd573b228b5dbfaec4001faae3b68 417 Gene3D G3DSA:3.20.20.10 23 255 1.1E-38 T 29-03-2018 IPR029066 PLP-binding barrel SMALA_RS33560 2b1fd573b228b5dbfaec4001faae3b68 417 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 42 60 9.3E-9 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMALA_RS33560 2b1fd573b228b5dbfaec4001faae3b68 417 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 62 74 9.3E-9 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMALA_RS33560 2b1fd573b228b5dbfaec4001faae3b68 417 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 262 281 9.3E-9 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMALA_RS33560 2b1fd573b228b5dbfaec4001faae3b68 417 Gene3D G3DSA:2.40.37.10 256 406 4.5E-33 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 SMALA_RS08075 8b44141a32ba8c2f9d83c9ae8b9ced4b 332 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 22 314 2.6E-97 T 29-03-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 SMALA_RS08075 8b44141a32ba8c2f9d83c9ae8b9ced4b 332 Pfam PF00005 ABC transporter 30 173 1.3E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS08075 8b44141a32ba8c2f9d83c9ae8b9ced4b 332 SUPERFAMILY SSF52540 10 235 7.78E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS08075 8b44141a32ba8c2f9d83c9ae8b9ced4b 332 Gene3D G3DSA:3.40.50.300 12 298 4.0E-64 T 29-03-2018 SMALA_RS08075 8b44141a32ba8c2f9d83c9ae8b9ced4b 332 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS08075 8b44141a32ba8c2f9d83c9ae8b9ced4b 332 SMART SM00382 39 222 2.5E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS05540 72aeb38696f8d457dfd3506a6b8f9099 577 Pfam PF02538 Hydantoinase B/oxoprolinase 8 527 6.8E-155 T 29-03-2018 IPR003692 Hydantoinase B/oxoprolinase GO:0003824 Reactome: R-HSA-174403 SMALA_RS04920 d4348255be07c14dbe1e1c4f8a46c9ae 310 SUPERFAMILY SSF46785 3 87 3.78E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS04920 d4348255be07c14dbe1e1c4f8a46c9ae 310 SUPERFAMILY SSF53850 88 292 6.92E-26 T 29-03-2018 SMALA_RS04920 d4348255be07c14dbe1e1c4f8a46c9ae 310 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.1E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS04920 d4348255be07c14dbe1e1c4f8a46c9ae 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 7.3E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS04920 d4348255be07c14dbe1e1c4f8a46c9ae 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 7.3E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS04920 d4348255be07c14dbe1e1c4f8a46c9ae 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 7.3E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS04920 d4348255be07c14dbe1e1c4f8a46c9ae 310 Gene3D G3DSA:3.40.190.10 91 175 1.3E-15 T 29-03-2018 SMALA_RS04920 d4348255be07c14dbe1e1c4f8a46c9ae 310 Gene3D G3DSA:3.40.190.10 176 266 4.8E-14 T 29-03-2018 SMALA_RS04920 d4348255be07c14dbe1e1c4f8a46c9ae 310 Pfam PF03466 LysR substrate binding domain 87 292 2.1E-26 T 29-03-2018 IPR005119 LysR, substrate-binding SMALA_RS04920 d4348255be07c14dbe1e1c4f8a46c9ae 310 Gene3D G3DSA:1.10.10.10 1 90 8.1E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS08480 6d65b16aef190ed219dce39ea4ec9ee1 173 Pfam PF01047 MarR family 58 116 2.0E-14 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS08480 6d65b16aef190ed219dce39ea4ec9ee1 173 SUPERFAMILY SSF46785 23 164 7.75E-34 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS08480 6d65b16aef190ed219dce39ea4ec9ee1 173 PRINTS PR00598 Bacterial regulatory protein MarR family signature 75 91 7.6E-5 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS08480 6d65b16aef190ed219dce39ea4ec9ee1 173 PRINTS PR00598 Bacterial regulatory protein MarR family signature 111 127 7.6E-5 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS08480 6d65b16aef190ed219dce39ea4ec9ee1 173 PRINTS PR00598 Bacterial regulatory protein MarR family signature 92 107 7.6E-5 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS08480 6d65b16aef190ed219dce39ea4ec9ee1 173 Gene3D G3DSA:1.10.10.10 14 172 2.0E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS08480 6d65b16aef190ed219dce39ea4ec9ee1 173 SMART SM00347 51 149 9.8E-23 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS05975 0a430c9cf011a2b1e156e0db8b151277 358 SUPERFAMILY SSF63829 56 350 1.63E-13 T 29-03-2018 SMALA_RS05975 0a430c9cf011a2b1e156e0db8b151277 358 Gene3D G3DSA:2.120.10.30 50 203 0.043 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like SMALA_RS05975 0a430c9cf011a2b1e156e0db8b151277 358 Gene3D G3DSA:2.120.10.30 204 357 4.0E-11 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like SMALA_RS36910 243469e357a619f7010c8dfb58e3c696 437 Pfam PF05977 Transmembrane secretion effector 36 432 2.3E-35 T 29-03-2018 IPR010290 Transmembrane secretion effector SMALA_RS36910 243469e357a619f7010c8dfb58e3c696 437 Gene3D G3DSA:1.20.1250.20 34 230 2.9E-23 T 29-03-2018 SMALA_RS36910 243469e357a619f7010c8dfb58e3c696 437 Gene3D G3DSA:1.20.1250.20 239 436 4.2E-12 T 29-03-2018 SMALA_RS36910 243469e357a619f7010c8dfb58e3c696 437 SUPERFAMILY SSF103473 32 433 1.57E-39 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS31255 0108ce088e55d1654764a5ccaea5db58 297 Gene3D G3DSA:3.40.190.10 172 253 8.7E-13 T 29-03-2018 SMALA_RS31255 0108ce088e55d1654764a5ccaea5db58 297 SUPERFAMILY SSF53850 88 281 1.33E-28 T 29-03-2018 SMALA_RS31255 0108ce088e55d1654764a5ccaea5db58 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 9.0E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS31255 0108ce088e55d1654764a5ccaea5db58 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 9.0E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS31255 0108ce088e55d1654764a5ccaea5db58 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 9.0E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS31255 0108ce088e55d1654764a5ccaea5db58 297 Gene3D G3DSA:1.10.10.10 1 83 1.4E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS31255 0108ce088e55d1654764a5ccaea5db58 297 Gene3D G3DSA:3.40.190.10 90 171 5.5E-18 T 29-03-2018 SMALA_RS31255 0108ce088e55d1654764a5ccaea5db58 297 SUPERFAMILY SSF46785 1 109 3.99E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS31255 0108ce088e55d1654764a5ccaea5db58 297 Pfam PF03466 LysR substrate binding domain 87 272 3.1E-29 T 29-03-2018 IPR005119 LysR, substrate-binding SMALA_RS31255 0108ce088e55d1654764a5ccaea5db58 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 7.5E-21 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS03840 063e62f2451f4cd9cb7b82e2d32688b6 404 SUPERFAMILY SSF53448 43 268 2.73E-38 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS03840 063e62f2451f4cd9cb7b82e2d32688b6 404 Pfam PF13641 Glycosyltransferase like family 2 49 268 2.7E-22 T 29-03-2018 SMALA_RS03840 063e62f2451f4cd9cb7b82e2d32688b6 404 Gene3D G3DSA:3.90.550.10 22 307 4.3E-44 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS03840 063e62f2451f4cd9cb7b82e2d32688b6 404 TIGRFAM TIGR03469 HpnB: hopene-associated glycosyltransferase HpnB 5 398 6.0E-147 T 29-03-2018 IPR017832 Glycosyl transferase, family 2, hopene-associated, HpnB SMALA_RS23155 76daa63ec774a33d020169818ae9cd26 388 PIRSF PIRSF000429 9 383 2.4E-18 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 SMALA_RS23155 76daa63ec774a33d020169818ae9cd26 388 Gene3D G3DSA:3.40.47.10 149 381 2.1E-20 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS23155 76daa63ec774a33d020169818ae9cd26 388 Gene3D G3DSA:3.40.47.10 3 125 0.0021 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS23155 76daa63ec774a33d020169818ae9cd26 388 SUPERFAMILY SSF53901 257 360 5.97E-13 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS23155 76daa63ec774a33d020169818ae9cd26 388 SUPERFAMILY SSF53901 15 234 5.24E-15 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS23000 7552f367d7576dc2917ef651fa4885e4 679 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 25 48 - T 29-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 SMALA_RS23000 7552f367d7576dc2917ef651fa4885e4 679 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 142 154 - T 29-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMALA_RS23000 7552f367d7576dc2917ef651fa4885e4 679 Gene3D G3DSA:3.40.1000.10 543 678 2.0E-11 T 29-03-2018 SMALA_RS23000 7552f367d7576dc2917ef651fa4885e4 679 Gene3D G3DSA:1.10.510.10 106 338 4.4E-45 T 29-03-2018 SMALA_RS23000 7552f367d7576dc2917ef651fa4885e4 679 Pfam PF00069 Protein kinase domain 19 275 1.5E-44 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMALA_RS23000 7552f367d7576dc2917ef651fa4885e4 679 SUPERFAMILY SSF56112 16 282 2.43E-65 T 29-03-2018 IPR011009 Protein kinase-like domain SMALA_RS23000 7552f367d7576dc2917ef651fa4885e4 679 Gene3D G3DSA:3.30.200.20 1 105 1.0E-21 T 29-03-2018 SMALA_RS23000 7552f367d7576dc2917ef651fa4885e4 679 SMART SM00220 19 277 2.5E-53 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMALA_RS32925 2c40e5431721ddd3b6b9ca9dbbbc7128 189 Pfam PF02699 Preprotein translocase subunit 5 78 3.6E-16 T 29-03-2018 IPR003849 Preprotein translocase YajC SMALA_RS32925 2c40e5431721ddd3b6b9ca9dbbbc7128 189 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 4 82 7.6E-15 T 29-03-2018 IPR003849 Preprotein translocase YajC SMALA_RS32925 2c40e5431721ddd3b6b9ca9dbbbc7128 189 SMART SM01323 1 82 9.4E-20 T 29-03-2018 IPR003849 Preprotein translocase YajC SMALA_RS34530 2ae9ad08033ec6c14490b763af326b2d 155 Pfam PF12802 MarR family 40 99 4.4E-10 T 29-03-2018 SMALA_RS34530 2ae9ad08033ec6c14490b763af326b2d 155 SUPERFAMILY SSF46785 6 151 9.97E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS34530 2ae9ad08033ec6c14490b763af326b2d 155 SMART SM00347 32 136 6.3E-8 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS34530 2ae9ad08033ec6c14490b763af326b2d 155 Gene3D G3DSA:1.10.10.10 4 155 9.8E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS02435 310e9db8b366ee3f956f67d5d4c211cd 284 Gene3D G3DSA:3.40.390.10 63 241 3.3E-4 T 29-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 SMALA_RS02435 310e9db8b366ee3f956f67d5d4c211cd 284 SUPERFAMILY SSF55486 181 277 3.29E-6 T 29-03-2018 SMALA_RS09165 39df43943d4034288fe4684af18f140c 426 Pfam PF01384 Phosphate transporter family 22 322 3.2E-77 T 29-03-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 SMALA_RS13585 9753757a43937b7a068105e76d0ba3aa 141 Gene3D G3DSA:1.20.120.620 22 122 3.0E-9 T 29-03-2018 SMALA_RS01515 10b660556fee9833a5e5320bfc501902 834 SUPERFAMILY SSF52279 562 718 8.76E-45 T 29-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 SMALA_RS01515 10b660556fee9833a5e5320bfc501902 834 SUPERFAMILY SSF52279 360 429 8.76E-45 T 29-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 SMALA_RS01515 10b660556fee9833a5e5320bfc501902 834 Gene3D G3DSA:3.40.50.1700 345 715 9.3E-68 T 29-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 SMALA_RS01515 10b660556fee9833a5e5320bfc501902 834 SUPERFAMILY SSF51445 44 338 2.53E-95 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS01515 10b660556fee9833a5e5320bfc501902 834 SMART SM01217 748 819 5.0E-22 T 29-03-2018 IPR026891 Fibronectin type III-like domain SMALA_RS01515 10b660556fee9833a5e5320bfc501902 834 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 360 715 3.3E-51 T 29-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 SMALA_RS01515 10b660556fee9833a5e5320bfc501902 834 Pfam PF14310 Fibronectin type III-like domain 748 819 3.7E-19 T 29-03-2018 IPR026891 Fibronectin type III-like domain SMALA_RS01515 10b660556fee9833a5e5320bfc501902 834 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 88 325 1.5E-57 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SMALA_RS01515 10b660556fee9833a5e5320bfc501902 834 Gene3D G3DSA:2.60.40.10 716 833 3.3E-32 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS01515 10b660556fee9833a5e5320bfc501902 834 PRINTS PR00133 Glycosyl hydrolase family 3 signature 158 174 1.4E-30 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SMALA_RS01515 10b660556fee9833a5e5320bfc501902 834 PRINTS PR00133 Glycosyl hydrolase family 3 signature 258 276 1.4E-30 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SMALA_RS01515 10b660556fee9833a5e5320bfc501902 834 PRINTS PR00133 Glycosyl hydrolase family 3 signature 189 205 1.4E-30 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SMALA_RS01515 10b660556fee9833a5e5320bfc501902 834 PRINTS PR00133 Glycosyl hydrolase family 3 signature 88 104 1.4E-30 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SMALA_RS01515 10b660556fee9833a5e5320bfc501902 834 PRINTS PR00133 Glycosyl hydrolase family 3 signature 112 131 1.4E-30 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SMALA_RS01515 10b660556fee9833a5e5320bfc501902 834 Gene3D G3DSA:3.20.20.300 28 333 2.0E-105 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SMALA_RS13075 4118f838dae33df4c3d26f4aa9443c97 203 SUPERFAMILY SSF52374 10 201 4.38E-51 T 29-03-2018 SMALA_RS13075 4118f838dae33df4c3d26f4aa9443c97 203 Gene3D G3DSA:3.40.50.620 5 201 3.1E-52 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS13075 4118f838dae33df4c3d26f4aa9443c97 203 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 13 76 6.4E-11 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 SMALA_RS13075 4118f838dae33df4c3d26f4aa9443c97 203 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 14 199 1.7E-52 T 29-03-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 SMALA_RS13075 4118f838dae33df4c3d26f4aa9443c97 203 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 10 200 30.15 T 29-03-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 SMALA_RS13075 4118f838dae33df4c3d26f4aa9443c97 203 Pfam PF01467 Cytidylyltransferase-like 14 174 2.5E-29 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 SMALA_RS28440 39443ffb86cd183818a434ff16d29c0c 571 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 9 565 2.2E-173 T 29-03-2018 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 SMALA_RS28440 39443ffb86cd183818a434ff16d29c0c 571 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 101 462 6.0E-41 T 29-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMALA_RS28440 39443ffb86cd183818a434ff16d29c0c 571 Pfam PF03129 Anticodon binding domain 480 568 3.1E-16 T 29-03-2018 IPR004154 Anticodon-binding SMALA_RS28440 39443ffb86cd183818a434ff16d29c0c 571 Gene3D G3DSA:3.90.960.10 258 393 4.0E-38 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 SMALA_RS28440 39443ffb86cd183818a434ff16d29c0c 571 Pfam PF04073 Aminoacyl-tRNA editing domain 263 379 7.8E-27 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 SMALA_RS28440 39443ffb86cd183818a434ff16d29c0c 571 Gene3D G3DSA:3.30.930.10 401 462 2.9E-8 T 29-03-2018 SMALA_RS28440 39443ffb86cd183818a434ff16d29c0c 571 Gene3D G3DSA:3.30.930.10 32 257 2.5E-61 T 29-03-2018 SMALA_RS28440 39443ffb86cd183818a434ff16d29c0c 571 SUPERFAMILY SSF52954 468 569 3.93E-25 T 29-03-2018 IPR004154 Anticodon-binding SMALA_RS28440 39443ffb86cd183818a434ff16d29c0c 571 SUPERFAMILY SSF55826 225 392 8.63E-21 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 SMALA_RS28440 39443ffb86cd183818a434ff16d29c0c 571 Hamap MF_01569 Proline--tRNA ligase [proS]. 8 571 36.425 T 29-03-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 SMALA_RS28440 39443ffb86cd183818a434ff16d29c0c 571 PRINTS PR01046 Prolyl-tRNA synthetase signature 151 162 1.2E-15 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 SMALA_RS28440 39443ffb86cd183818a434ff16d29c0c 571 PRINTS PR01046 Prolyl-tRNA synthetase signature 111 122 1.2E-15 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 SMALA_RS28440 39443ffb86cd183818a434ff16d29c0c 571 PRINTS PR01046 Prolyl-tRNA synthetase signature 75 93 1.2E-15 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 SMALA_RS28440 39443ffb86cd183818a434ff16d29c0c 571 PRINTS PR01046 Prolyl-tRNA synthetase signature 141 149 1.2E-15 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 SMALA_RS28440 39443ffb86cd183818a434ff16d29c0c 571 Gene3D G3DSA:3.40.50.800 463 570 2.8E-27 T 29-03-2018 IPR004154 Anticodon-binding SMALA_RS28440 39443ffb86cd183818a434ff16d29c0c 571 SUPERFAMILY SSF55681 411 482 5.18E-90 T 29-03-2018 SMALA_RS28440 39443ffb86cd183818a434ff16d29c0c 571 SUPERFAMILY SSF55681 17 244 5.18E-90 T 29-03-2018 SMALA_RS03700 ce562ffac9d3c9be0436a38212df9e11 200 SMART SM00830 39 117 1.8E-18 T 29-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 SMALA_RS03700 ce562ffac9d3c9be0436a38212df9e11 200 PIRSF PIRSF026640 12 200 5.7E-46 T 29-03-2018 IPR008240 Chorismate mutase, periplasmic KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 SMALA_RS03700 ce562ffac9d3c9be0436a38212df9e11 200 TIGRFAM TIGR01806 CM_mono2: putative chorismate mutase 44 153 2.8E-30 T 29-03-2018 IPR008240 Chorismate mutase, periplasmic KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 SMALA_RS03700 ce562ffac9d3c9be0436a38212df9e11 200 Gene3D G3DSA:1.20.59.10 45 123 5.2E-19 T 29-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 SMALA_RS03700 ce562ffac9d3c9be0436a38212df9e11 200 Pfam PF01817 Chorismate mutase type II 47 114 4.4E-11 T 29-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 SMALA_RS03700 ce562ffac9d3c9be0436a38212df9e11 200 SUPERFAMILY SSF48600 44 198 5.34E-37 T 29-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 SMALA_RS35165 1f8bb89179e094d532fa92dfdc61e315 230 PIRSF PIRSF004749 3 203 4.2E-50 T 29-03-2018 IPR023635 Peptide deformylase SMALA_RS35165 1f8bb89179e094d532fa92dfdc61e315 230 Hamap MF_00163 Peptide deformylase [def]. 18 186 25.004 T 29-03-2018 IPR023635 Peptide deformylase SMALA_RS35165 1f8bb89179e094d532fa92dfdc61e315 230 Gene3D G3DSA:3.90.45.10 4 204 8.5E-55 T 29-03-2018 IPR023635 Peptide deformylase SMALA_RS35165 1f8bb89179e094d532fa92dfdc61e315 230 SUPERFAMILY SSF56420 18 181 1.57E-47 T 29-03-2018 IPR023635 Peptide deformylase SMALA_RS35165 1f8bb89179e094d532fa92dfdc61e315 230 PRINTS PR01576 Peptide deformylase signature 151 180 9.8E-33 T 29-03-2018 IPR023635 Peptide deformylase SMALA_RS35165 1f8bb89179e094d532fa92dfdc61e315 230 PRINTS PR01576 Peptide deformylase signature 132 150 9.8E-33 T 29-03-2018 IPR023635 Peptide deformylase SMALA_RS35165 1f8bb89179e094d532fa92dfdc61e315 230 PRINTS PR01576 Peptide deformylase signature 120 131 9.8E-33 T 29-03-2018 IPR023635 Peptide deformylase SMALA_RS35165 1f8bb89179e094d532fa92dfdc61e315 230 PRINTS PR01576 Peptide deformylase signature 51 80 9.8E-33 T 29-03-2018 IPR023635 Peptide deformylase SMALA_RS35165 1f8bb89179e094d532fa92dfdc61e315 230 Pfam PF01327 Polypeptide deformylase 21 180 1.4E-42 T 29-03-2018 IPR023635 Peptide deformylase SMALA_RS29825 98ff876e3510ebaf6e307b900672991c 405 ProSitePatterns PS00737 Thiolases signature 2. 344 360 - T 29-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 SMALA_RS29825 98ff876e3510ebaf6e307b900672991c 405 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 11 397 6.3E-131 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 SMALA_RS29825 98ff876e3510ebaf6e307b900672991c 405 Gene3D G3DSA:3.40.47.10 150 273 3.2E-19 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS29825 98ff876e3510ebaf6e307b900672991c 405 Gene3D G3DSA:3.40.47.10 1 149 2.4E-24 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS29825 98ff876e3510ebaf6e307b900672991c 405 PIRSF PIRSF000429 3 400 2.0E-122 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 SMALA_RS29825 98ff876e3510ebaf6e307b900672991c 405 Pfam PF02803 Thiolase, C-terminal domain 276 397 5.9E-37 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 SMALA_RS29825 98ff876e3510ebaf6e307b900672991c 405 SUPERFAMILY SSF53901 276 397 7.74E-39 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS29825 98ff876e3510ebaf6e307b900672991c 405 Gene3D G3DSA:3.40.47.10 274 396 7.6E-28 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS29825 98ff876e3510ebaf6e307b900672991c 405 Pfam PF00108 Thiolase, N-terminal domain 8 266 1.6E-57 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 SMALA_RS29825 98ff876e3510ebaf6e307b900672991c 405 SUPERFAMILY SSF53901 7 273 1.78E-58 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS34635 d88750248eb441c04676f539f7c25f60 250 SUPERFAMILY SSF51735 3 250 1.0E-77 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS34635 d88750248eb441c04676f539f7c25f60 250 Gene3D G3DSA:3.40.50.720 2 34 2.3E-5 T 29-03-2018 SMALA_RS34635 d88750248eb441c04676f539f7c25f60 250 Gene3D G3DSA:3.40.50.720 35 250 1.1E-66 T 29-03-2018 SMALA_RS34635 d88750248eb441c04676f539f7c25f60 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 1.7E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS34635 d88750248eb441c04676f539f7c25f60 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 1.7E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS34635 d88750248eb441c04676f539f7c25f60 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 1.7E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS34635 d88750248eb441c04676f539f7c25f60 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 1.7E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS34635 d88750248eb441c04676f539f7c25f60 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 1.7E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS34635 d88750248eb441c04676f539f7c25f60 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 1.7E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS34635 d88750248eb441c04676f539f7c25f60 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 1.7E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS34635 d88750248eb441c04676f539f7c25f60 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 1.7E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS34635 d88750248eb441c04676f539f7c25f60 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 1.7E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS34635 d88750248eb441c04676f539f7c25f60 250 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 250 4.5E-59 T 29-03-2018 SMALA_RS34635 d88750248eb441c04676f539f7c25f60 250 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 212 0.0011 T 29-03-2018 SMALA_RS26850 6d729844c656645d175db589ba8c0cd3 74 PRINTS PR01249 Ribosomal protein L31 signature 32 47 3.1E-20 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS26850 6d729844c656645d175db589ba8c0cd3 74 PRINTS PR01249 Ribosomal protein L31 signature 47 65 3.1E-20 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS26850 6d729844c656645d175db589ba8c0cd3 74 PRINTS PR01249 Ribosomal protein L31 signature 2 19 3.1E-20 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS26850 6d729844c656645d175db589ba8c0cd3 74 Pfam PF01197 Ribosomal protein L31 2 66 3.4E-29 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS26850 6d729844c656645d175db589ba8c0cd3 74 TIGRFAM TIGR00105 L31: ribosomal protein bL31 2 67 2.6E-32 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS26850 6d729844c656645d175db589ba8c0cd3 74 Hamap MF_00501 50S ribosomal protein L31 [rpmE]. 1 69 28.61 T 29-03-2018 IPR027491 Ribosomal protein L31 type A GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS26850 6d729844c656645d175db589ba8c0cd3 74 ProSitePatterns PS01143 Ribosomal protein L31 signature. 36 57 - T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS26850 6d729844c656645d175db589ba8c0cd3 74 SUPERFAMILY SSF143800 1 66 5.49E-24 T 29-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS33120 6e5e1179a36450a28b0c153989bcacf2 107 SUPERFAMILY SSF46946 56 102 1.69E-7 T 29-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 SMALA_RS33120 6e5e1179a36450a28b0c153989bcacf2 107 Gene3D G3DSA:1.10.8.50 68 101 2.3E-5 T 29-03-2018 SMALA_RS33120 6e5e1179a36450a28b0c153989bcacf2 107 PIRSF PIRSF002134 37 104 5.9E-9 T 29-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMALA_RS33120 6e5e1179a36450a28b0c153989bcacf2 107 Gene3D G3DSA:1.10.150.20 10 67 0.039 T 29-03-2018 SMALA_RS29400 50d70996b5cef3c4a3771a4ae1d78679 257 Pfam PF00975 Thioesterase domain 25 246 4.3E-45 T 29-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 SMALA_RS29400 50d70996b5cef3c4a3771a4ae1d78679 257 SUPERFAMILY SSF53474 17 249 1.28E-45 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS29400 50d70996b5cef3c4a3771a4ae1d78679 257 Gene3D G3DSA:3.40.50.1820 4 252 3.9E-32 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS41040 86a4fd911b6a883864030b4af928949c 94 Pfam PF07702 UTRA domain 12 80 7.6E-8 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMALA_RS41040 86a4fd911b6a883864030b4af928949c 94 SUPERFAMILY SSF64288 12 85 6.12E-11 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMALA_RS41040 86a4fd911b6a883864030b4af928949c 94 Gene3D G3DSA:3.40.1410.10 2 87 2.3E-12 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMALA_RS36180 497b3352615905136e9e4cd1d17a0561 381 SUPERFAMILY SSF81606 156 354 1.02E-6 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS36180 497b3352615905136e9e4cd1d17a0561 381 SMART SM00331 144 371 4.3E-37 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS36180 497b3352615905136e9e4cd1d17a0561 381 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 172 371 3.6E-38 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS36180 497b3352615905136e9e4cd1d17a0561 381 Gene3D G3DSA:3.60.40.10 107 374 1.1E-27 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS14190 6fb88b60daf91e8474d006ff44a04120 550 SUPERFAMILY SSF52096 240 524 2.65E-87 T 29-03-2018 IPR029045 ClpP/crotonase-like domain SMALA_RS14190 6fb88b60daf91e8474d006ff44a04120 550 Gene3D G3DSA:3.90.226.10 13 280 4.0E-67 T 29-03-2018 SMALA_RS14190 6fb88b60daf91e8474d006ff44a04120 550 Gene3D G3DSA:3.90.226.10 282 540 1.0E-72 T 29-03-2018 SMALA_RS14190 6fb88b60daf91e8474d006ff44a04120 550 Pfam PF01039 Carboxyl transferase domain 51 530 1.1E-150 T 29-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 SMALA_RS14190 6fb88b60daf91e8474d006ff44a04120 550 SUPERFAMILY SSF52096 29 273 1.48E-73 T 29-03-2018 IPR029045 ClpP/crotonase-like domain SMALA_RS09985 700e7e772ef44b009fa10b0130d9ccdb 496 SUPERFAMILY SSF56322 14 488 1.96E-157 T 29-03-2018 IPR005801 ADC synthase GO:0009058 SMALA_RS09985 700e7e772ef44b009fa10b0130d9ccdb 496 Gene3D G3DSA:3.60.120.10 14 492 1.1E-165 T 29-03-2018 IPR005801 ADC synthase GO:0009058 SMALA_RS09985 700e7e772ef44b009fa10b0130d9ccdb 496 Pfam PF00425 chorismate binding enzyme 228 480 9.9E-98 T 29-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal SMALA_RS09985 700e7e772ef44b009fa10b0130d9ccdb 496 TIGRFAM TIGR00564 trpE_most: anthranilate synthase component I 25 489 1.9E-173 T 29-03-2018 IPR005256 Anthranilate synthase component I, PabB-like GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 SMALA_RS09985 700e7e772ef44b009fa10b0130d9ccdb 496 Pfam PF04715 Anthranilate synthase component I, N terminal region 26 169 4.7E-31 T 29-03-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 SMALA_RS09985 700e7e772ef44b009fa10b0130d9ccdb 496 PRINTS PR00095 Anthranilate synthase component I signature 342 355 6.1E-24 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 SMALA_RS09985 700e7e772ef44b009fa10b0130d9ccdb 496 PRINTS PR00095 Anthranilate synthase component I signature 328 341 6.1E-24 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 SMALA_RS09985 700e7e772ef44b009fa10b0130d9ccdb 496 PRINTS PR00095 Anthranilate synthase component I signature 437 451 6.1E-24 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 SMALA_RS09985 700e7e772ef44b009fa10b0130d9ccdb 496 PRINTS PR00095 Anthranilate synthase component I signature 422 436 6.1E-24 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 SMALA_RS13885 c2f0cef3893d167c67671f5ced194fcd 336 Gene3D G3DSA:3.40.50.2300 164 336 7.7E-19 T 29-03-2018 SMALA_RS13885 c2f0cef3893d167c67671f5ced194fcd 336 SUPERFAMILY SSF53822 52 325 2.54E-54 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SMALA_RS13885 c2f0cef3893d167c67671f5ced194fcd 336 Gene3D G3DSA:3.40.50.2300 52 163 3.3E-21 T 29-03-2018 SMALA_RS13885 c2f0cef3893d167c67671f5ced194fcd 336 Pfam PF13407 Periplasmic binding protein domain 56 300 3.2E-41 T 29-03-2018 IPR025997 Periplasmic binding protein SMALA_RS31505 c651c8677adbe8c5e417ec92d7d51955 353 Gene3D G3DSA:3.20.20.30 11 346 7.1E-80 T 29-03-2018 SMALA_RS31505 c651c8677adbe8c5e417ec92d7d51955 353 SUPERFAMILY SSF51679 93 345 8.9E-76 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS31505 c651c8677adbe8c5e417ec92d7d51955 353 SUPERFAMILY SSF51679 31 60 8.9E-76 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS31505 c651c8677adbe8c5e417ec92d7d51955 353 Pfam PF00296 Luciferase-like monooxygenase 33 285 2.4E-54 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS31505 c651c8677adbe8c5e417ec92d7d51955 353 TIGRFAM TIGR03619 F420_Rv2161c: probable F420-dependent oxidoreductase, Rv2161c family 40 323 2.8E-56 T 29-03-2018 IPR019921 Luciferase-like, F420-dependent oxidoreductase, Rv2161c, predicted SMALA_RS40325 0b463144a44904acf28e010c74f7123d 320 SUPERFAMILY SSF54637 190 316 4.48E-15 T 29-03-2018 IPR029069 HotDog domain SMALA_RS40325 0b463144a44904acf28e010c74f7123d 320 Gene3D G3DSA:3.10.129.10 182 318 1.8E-14 T 29-03-2018 SMALA_RS40325 0b463144a44904acf28e010c74f7123d 320 Gene3D G3DSA:3.10.129.10 18 162 2.8E-14 T 29-03-2018 SMALA_RS40325 0b463144a44904acf28e010c74f7123d 320 SUPERFAMILY SSF54637 24 147 2.82E-13 T 29-03-2018 IPR029069 HotDog domain SMALA_RS40325 0b463144a44904acf28e010c74f7123d 320 Pfam PF01575 MaoC like domain 184 281 1.1E-7 T 29-03-2018 IPR002539 MaoC-like domain SMALA_RS32620 0e7a46f8faaeef9488a8514aa912a8f1 290 Gene3D G3DSA:3.20.20.70 3 197 4.8E-24 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS32620 0e7a46f8faaeef9488a8514aa912a8f1 290 Pfam PF04055 Radical SAM superfamily 10 149 1.5E-10 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 SMALA_RS32620 0e7a46f8faaeef9488a8514aa912a8f1 290 Pfam PF13186 Iron-sulfur cluster-binding domain 201 257 5.1E-7 T 29-03-2018 IPR023885 4Fe4S-binding SPASM domain SMALA_RS32620 0e7a46f8faaeef9488a8514aa912a8f1 290 SUPERFAMILY SSF102114 6 246 4.58E-37 T 29-03-2018 SMALA_RS07295 bc19bcf84e156e1078d16cb43a815974 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 188 3.0E-15 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS07295 bc19bcf84e156e1078d16cb43a815974 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 172 3.0E-15 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS07295 bc19bcf84e156e1078d16cb43a815974 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 188 200 3.0E-15 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS07295 bc19bcf84e156e1078d16cb43a815974 223 Gene3D G3DSA:1.10.10.10 130 222 2.0E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS07295 bc19bcf84e156e1078d16cb43a815974 223 SUPERFAMILY SSF52172 3 137 2.99E-35 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS07295 bc19bcf84e156e1078d16cb43a815974 223 ProSitePatterns PS00622 LuxR-type HTH domain signature. 172 199 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS07295 bc19bcf84e156e1078d16cb43a815974 223 Gene3D G3DSA:3.40.50.2300 2 129 1.7E-40 T 29-03-2018 SMALA_RS07295 bc19bcf84e156e1078d16cb43a815974 223 SMART SM00421 155 212 2.1E-28 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS07295 bc19bcf84e156e1078d16cb43a815974 223 SMART SM00448 3 118 6.8E-36 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS07295 bc19bcf84e156e1078d16cb43a815974 223 Pfam PF00196 Bacterial regulatory proteins, luxR family 157 212 1.3E-21 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS07295 bc19bcf84e156e1078d16cb43a815974 223 Pfam PF00072 Response regulator receiver domain 5 119 3.6E-28 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS07295 bc19bcf84e156e1078d16cb43a815974 223 SUPERFAMILY SSF46894 148 218 3.4E-23 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS08065 26f190a84b77d10ea504167f7e6433f4 172 Gene3D G3DSA:1.10.1220.10 110 149 7.6E-13 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 SMALA_RS08065 26f190a84b77d10ea504167f7e6433f4 172 SUPERFAMILY SSF47598 109 158 5.08E-11 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 SMALA_RS08065 26f190a84b77d10ea504167f7e6433f4 172 Pfam PF05534 HicB family 114 143 6.7E-5 T 29-03-2018 IPR008651 Uncharacterised protein family HicB SMALA_RS25730 7def257e5061dc62aa92d967381d7323 423 Pfam PF07730 Histidine kinase 222 288 2.3E-18 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMALA_RS25730 7def257e5061dc62aa92d967381d7323 423 SUPERFAMILY SSF55874 318 410 1.58E-12 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS25730 7def257e5061dc62aa92d967381d7323 423 Gene3D G3DSA:3.30.565.10 258 417 7.2E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS41290 82095b0fe0819227f964ba4145cd8c78 175 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 8 78 4.9E-11 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SMALA_RS41290 82095b0fe0819227f964ba4145cd8c78 175 SMART SM00855 7 119 9.3E-5 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SMALA_RS41290 82095b0fe0819227f964ba4145cd8c78 175 Gene3D G3DSA:3.40.50.1240 2 172 4.1E-31 T 29-03-2018 IPR029033 Histidine phosphatase superfamily SMALA_RS41290 82095b0fe0819227f964ba4145cd8c78 175 SUPERFAMILY SSF53254 6 154 8.14E-22 T 29-03-2018 IPR029033 Histidine phosphatase superfamily SMALA_RS15135 cb9b1fc7776ea6b7b36cc7ee18f6cc21 204 Gene3D G3DSA:1.10.10.10 7 180 1.5E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS15135 cb9b1fc7776ea6b7b36cc7ee18f6cc21 204 Pfam PF12840 Helix-turn-helix domain 29 82 1.6E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS15135 cb9b1fc7776ea6b7b36cc7ee18f6cc21 204 SUPERFAMILY SSF46785 25 98 8.83E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS15135 cb9b1fc7776ea6b7b36cc7ee18f6cc21 204 SMART SM00418 24 121 1.3E-9 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS22305 4c021600d255c1d44ad05f4cf0c42647 545 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 330 349 2.9E-27 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS22305 4c021600d255c1d44ad05f4cf0c42647 545 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 251 275 2.9E-27 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS22305 4c021600d255c1d44ad05f4cf0c42647 545 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 149 168 2.9E-27 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS22305 4c021600d255c1d44ad05f4cf0c42647 545 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 179 203 2.9E-27 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS22305 4c021600d255c1d44ad05f4cf0c42647 545 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 10 541 6.1E-159 T 29-03-2018 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS22305 4c021600d255c1d44ad05f4cf0c42647 545 Pfam PF00361 Proton-conducting membrane transporter 332 445 2.0E-20 T 29-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS22305 4c021600d255c1d44ad05f4cf0c42647 545 Pfam PF00361 Proton-conducting membrane transporter 145 309 4.1E-40 T 29-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS26990 3119dd930826dd4fd2529ee0b706e1cf 330 PRINTS PR00069 Aldo-keto reductase signature 140 157 1.7E-10 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMALA_RS26990 3119dd930826dd4fd2529ee0b706e1cf 330 PRINTS PR00069 Aldo-keto reductase signature 240 264 1.7E-10 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMALA_RS26990 3119dd930826dd4fd2529ee0b706e1cf 330 PRINTS PR00069 Aldo-keto reductase signature 43 67 1.7E-10 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMALA_RS26990 3119dd930826dd4fd2529ee0b706e1cf 330 PRINTS PR00069 Aldo-keto reductase signature 109 127 1.7E-10 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMALA_RS26990 3119dd930826dd4fd2529ee0b706e1cf 330 Gene3D G3DSA:3.20.20.100 1 328 5.9E-95 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS26990 3119dd930826dd4fd2529ee0b706e1cf 330 Pfam PF00248 Aldo/keto reductase family 17 310 1.4E-67 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS26990 3119dd930826dd4fd2529ee0b706e1cf 330 SUPERFAMILY SSF51430 4 311 1.83E-93 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS26620 8829ae5aa6dd5fabd1d62af616e93d91 130 Pfam PF05331 Protein of unknown function (DUF742) 11 130 1.3E-37 T 29-03-2018 IPR007995 Protein of unknown function DUF742 SMALA_RS03280 9e4b3402ce56582dca5689eccfdbe6ec 142 Gene3D G3DSA:3.30.530.20 1 141 2.8E-24 T 29-03-2018 IPR023393 START-like domain SMALA_RS03280 9e4b3402ce56582dca5689eccfdbe6ec 142 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 1 137 7.5E-21 T 29-03-2018 IPR019587 Polyketide cyclase/dehydrase SMALA_RS03280 9e4b3402ce56582dca5689eccfdbe6ec 142 SUPERFAMILY SSF55961 1 141 2.92E-22 T 29-03-2018 SMALA_RS22470 37c226dab14e800f90c2c98402d781ab 401 PRINTS PR01217 Proline rich extensin signature 5 21 4.7E-9 T 29-03-2018 SMALA_RS22470 37c226dab14e800f90c2c98402d781ab 401 PRINTS PR01217 Proline rich extensin signature 32 44 4.7E-9 T 29-03-2018 SMALA_RS22470 37c226dab14e800f90c2c98402d781ab 401 PRINTS PR01217 Proline rich extensin signature 44 65 4.7E-9 T 29-03-2018 SMALA_RS22470 37c226dab14e800f90c2c98402d781ab 401 PRINTS PR01217 Proline rich extensin signature 68 84 4.7E-9 T 29-03-2018 SMALA_RS22470 37c226dab14e800f90c2c98402d781ab 401 Pfam PF01435 Peptidase family M48 175 389 4.5E-17 T 29-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 SMALA_RS22470 37c226dab14e800f90c2c98402d781ab 401 Gene3D G3DSA:3.30.2010.10 164 252 5.5E-14 T 29-03-2018 SMALA_RS13895 1ed968db577362f913de01f1a6fe2d3b 296 Pfam PF00005 ABC transporter 42 196 3.5E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS13895 1ed968db577362f913de01f1a6fe2d3b 296 Gene3D G3DSA:3.40.50.300 23 280 3.9E-51 T 29-03-2018 SMALA_RS13895 1ed968db577362f913de01f1a6fe2d3b 296 SMART SM00382 51 243 9.3E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS13895 1ed968db577362f913de01f1a6fe2d3b 296 SUPERFAMILY SSF52540 24 246 1.25E-54 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS39500 45a908b4d0423bcaff4daa009d0b66b2 352 Pfam PF01032 FecCD transport family 32 346 3.6E-83 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 SMALA_RS39500 45a908b4d0423bcaff4daa009d0b66b2 352 Gene3D G3DSA:1.10.3470.10 16 352 8.1E-60 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SMALA_RS39500 45a908b4d0423bcaff4daa009d0b66b2 352 SUPERFAMILY SSF81345 17 346 6.67E-74 T 29-03-2018 IPR029022 ABC transporter, BtuC-like SMALA_RS23325 795311f867f415701f6580ea52404b11 275 Pfam PF13460 NAD(P)H-binding 6 172 6.5E-18 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS23325 795311f867f415701f6580ea52404b11 275 SUPERFAMILY SSF51735 3 266 8.14E-46 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS23325 795311f867f415701f6580ea52404b11 275 Gene3D G3DSA:3.40.50.720 2 274 1.9E-29 T 29-03-2018 SMALA_RS21530 19bdc9a7c687b9b1990b38412680096d 340 Gene3D G3DSA:3.40.50.2300 57 177 6.0E-31 T 29-03-2018 SMALA_RS21530 19bdc9a7c687b9b1990b38412680096d 340 SUPERFAMILY SSF47413 3 62 1.13E-14 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS21530 19bdc9a7c687b9b1990b38412680096d 340 SMART SM00354 3 74 6.7E-27 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS21530 19bdc9a7c687b9b1990b38412680096d 340 Pfam PF00356 Bacterial regulatory proteins, lacI family 7 51 1.7E-14 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS21530 19bdc9a7c687b9b1990b38412680096d 340 SUPERFAMILY SSF53822 64 338 1.28E-59 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SMALA_RS21530 19bdc9a7c687b9b1990b38412680096d 340 Pfam PF13377 Periplasmic binding protein-like domain 171 337 4.2E-29 T 29-03-2018 SMALA_RS21530 19bdc9a7c687b9b1990b38412680096d 340 Gene3D G3DSA:3.40.50.2300 178 313 1.0E-34 T 29-03-2018 SMALA_RS21530 19bdc9a7c687b9b1990b38412680096d 340 Gene3D G3DSA:1.10.260.40 4 56 5.4E-20 T 29-03-2018 SMALA_RS37335 d91d1a5f46e510b610358c3dcc07dbae 271 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 244 4.0E-47 T 29-03-2018 SMALA_RS37335 d91d1a5f46e510b610358c3dcc07dbae 271 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 10 179 0.0016 T 29-03-2018 SMALA_RS37335 d91d1a5f46e510b610358c3dcc07dbae 271 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 9.5E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS37335 d91d1a5f46e510b610358c3dcc07dbae 271 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 9.5E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS37335 d91d1a5f46e510b610358c3dcc07dbae 271 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 9.5E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS37335 d91d1a5f46e510b610358c3dcc07dbae 271 Gene3D G3DSA:3.40.50.720 2 250 7.3E-62 T 29-03-2018 SMALA_RS37335 d91d1a5f46e510b610358c3dcc07dbae 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 1.6E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS37335 d91d1a5f46e510b610358c3dcc07dbae 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 1.6E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS37335 d91d1a5f46e510b610358c3dcc07dbae 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.6E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS37335 d91d1a5f46e510b610358c3dcc07dbae 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 1.6E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS37335 d91d1a5f46e510b610358c3dcc07dbae 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 1.6E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS37335 d91d1a5f46e510b610358c3dcc07dbae 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 1.6E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS37335 d91d1a5f46e510b610358c3dcc07dbae 271 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMALA_RS37335 d91d1a5f46e510b610358c3dcc07dbae 271 SUPERFAMILY SSF51735 9 244 1.7E-63 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS22260 014457179aeaeb014a8309c6eb3e534f 416 Gene3D G3DSA:3.30.565.10 273 396 4.5E-14 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS22260 014457179aeaeb014a8309c6eb3e534f 416 SUPERFAMILY SSF55874 286 394 3.56E-12 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS22260 014457179aeaeb014a8309c6eb3e534f 416 Pfam PF07730 Histidine kinase 208 272 2.5E-14 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMALA_RS22260 014457179aeaeb014a8309c6eb3e534f 416 Pfam PF13796 Putative sensor 40 157 3.7E-26 T 29-03-2018 IPR025828 Putative sensor domain SMALA_RS38095 e84b4769d67761599b6ed2d92d3b0054 200 Gene3D G3DSA:3.40.50.880 3 200 1.5E-55 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS38095 e84b4769d67761599b6ed2d92d3b0054 200 SUPERFAMILY SSF52317 7 197 3.05E-50 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS38095 e84b4769d67761599b6ed2d92d3b0054 200 Pfam PF01965 DJ-1/PfpI family 7 177 2.8E-24 T 29-03-2018 IPR002818 DJ-1/PfpI SMALA_RS42450 636c63a6a431e9b4460c9f27a2c31fb8 138 Gene3D G3DSA:3.30.70.100 1 96 5.1E-15 T 29-03-2018 SMALA_RS42450 636c63a6a431e9b4460c9f27a2c31fb8 138 Pfam PF07876 Stress responsive A/B Barrel Domain 2 92 2.7E-14 T 29-03-2018 IPR013097 Stress responsive alpha-beta barrel SMALA_RS42450 636c63a6a431e9b4460c9f27a2c31fb8 138 SMART SM00886 2 93 5.5E-13 T 29-03-2018 IPR013097 Stress responsive alpha-beta barrel SMALA_RS42450 636c63a6a431e9b4460c9f27a2c31fb8 138 SUPERFAMILY SSF54909 1 97 6.44E-18 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel SMALA_RS03875 ce721048833b04ce0ec81b52bb56e377 547 SMART SM00065 183 332 1.7E-11 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS03875 ce721048833b04ce0ec81b52bb56e377 547 SMART SM00065 16 162 1.9E-21 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS03875 ce721048833b04ce0ec81b52bb56e377 547 Gene3D G3DSA:3.30.450.40 1 166 8.7E-34 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS03875 ce721048833b04ce0ec81b52bb56e377 547 SUPERFAMILY SSF55874 447 534 1.23E-12 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS03875 ce721048833b04ce0ec81b52bb56e377 547 Pfam PF07730 Histidine kinase 340 402 5.9E-12 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMALA_RS03875 ce721048833b04ce0ec81b52bb56e377 547 SMART SM00387 446 535 3.8E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS03875 ce721048833b04ce0ec81b52bb56e377 547 SUPERFAMILY SSF55781 3 178 1.44E-38 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS03875 ce721048833b04ce0ec81b52bb56e377 547 SUPERFAMILY SSF55781 165 349 3.27E-25 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS03875 ce721048833b04ce0ec81b52bb56e377 547 Gene3D G3DSA:3.30.565.10 410 535 5.0E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS03875 ce721048833b04ce0ec81b52bb56e377 547 Gene3D G3DSA:3.30.450.40 167 336 3.3E-31 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS03875 ce721048833b04ce0ec81b52bb56e377 547 Pfam PF13185 GAF domain 185 323 2.0E-14 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS03875 ce721048833b04ce0ec81b52bb56e377 547 Pfam PF13185 GAF domain 15 153 1.4E-20 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS14305 c9e23880fb837c52e0a84030a3224314 283 SMART SM00530 19 74 1.0E-5 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS14305 c9e23880fb837c52e0a84030a3224314 283 SUPERFAMILY SSF47413 11 70 7.04E-10 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS14305 c9e23880fb837c52e0a84030a3224314 283 Pfam PF13560 Helix-turn-helix domain 16 72 3.1E-13 T 29-03-2018 SMALA_RS14305 c9e23880fb837c52e0a84030a3224314 283 Gene3D G3DSA:1.10.260.40 4 94 5.5E-14 T 29-03-2018 SMALA_RS42330 ebbbdcd1f448f096ff6b046e79a907a5 219 SUPERFAMILY SSF52833 47 217 4.55E-26 T 29-03-2018 IPR012336 Thioredoxin-like fold SMALA_RS42330 ebbbdcd1f448f096ff6b046e79a907a5 219 Pfam PF00578 AhpC/TSA family 49 195 9.5E-24 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 SMALA_RS42330 ebbbdcd1f448f096ff6b046e79a907a5 219 Gene3D G3DSA:3.40.30.10 32 218 5.6E-27 T 29-03-2018 SMALA_RS08640 3f9599c6d6964c9994e0439fc0893124 412 Pfam PF00534 Glycosyl transferases group 1 200 357 1.5E-37 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 SMALA_RS08640 3f9599c6d6964c9994e0439fc0893124 412 Gene3D G3DSA:3.40.50.2000 200 363 2.1E-41 T 29-03-2018 SMALA_RS08640 3f9599c6d6964c9994e0439fc0893124 412 Pfam PF13439 Glycosyltransferase Family 4 13 192 2.0E-11 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 SMALA_RS08640 3f9599c6d6964c9994e0439fc0893124 412 SUPERFAMILY SSF53756 4 376 4.89E-70 T 29-03-2018 SMALA_RS08640 3f9599c6d6964c9994e0439fc0893124 412 Gene3D G3DSA:3.40.50.2000 1 199 7.3E-12 T 29-03-2018 SMALA_RS10665 904966c210d66115fb9a123f5d549dbe 207 SUPERFAMILY SSF48008 78 199 6.54E-21 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS10665 904966c210d66115fb9a123f5d549dbe 207 Gene3D G3DSA:1.20.120.530 74 204 3.4E-25 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS10665 904966c210d66115fb9a123f5d549dbe 207 Gene3D G3DSA:1.10.10.10 5 73 2.8E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS10665 904966c210d66115fb9a123f5d549dbe 207 SMART SM00895 81 202 2.5E-12 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS10665 904966c210d66115fb9a123f5d549dbe 207 Pfam PF07729 FCD domain 81 200 2.2E-17 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS10665 904966c210d66115fb9a123f5d549dbe 207 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 71 4.3E-17 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS10665 904966c210d66115fb9a123f5d549dbe 207 SMART SM00345 13 71 7.0E-15 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS10665 904966c210d66115fb9a123f5d549dbe 207 SUPERFAMILY SSF46785 8 97 2.49E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS27000 dacb275c6e9759dfcc2d2b7f68ab403b 223 Pfam PF01939 Endonuclease NucS 4 223 6.0E-82 T 29-03-2018 IPR002793 Endonuclease NucS SMALA_RS27000 dacb275c6e9759dfcc2d2b7f68ab403b 223 Gene3D G3DSA:3.40.1350.10 109 173 0.0013 T 29-03-2018 SMALA_RS27000 dacb275c6e9759dfcc2d2b7f68ab403b 223 Hamap MF_00722 Endonuclease NucS [nucS]. 4 215 31.376 T 29-03-2018 IPR002793 Endonuclease NucS SMALA_RS11465 02a99d16168a860668ead8ebd8b4cfa7 427 SUPERFAMILY SSF48239 55 172 1.39E-21 T 29-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid SMALA_RS11465 02a99d16168a860668ead8ebd8b4cfa7 427 Gene3D G3DSA:1.50.10.20 124 405 4.2E-18 T 29-03-2018 SMALA_RS11465 02a99d16168a860668ead8ebd8b4cfa7 427 Gene3D G3DSA:1.50.10.20 4 123 1.6E-11 T 29-03-2018 SMALA_RS11465 02a99d16168a860668ead8ebd8b4cfa7 427 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 71 120 0.095 T 29-03-2018 IPR001330 PFTB repeat GO:0003824 SMALA_RS11465 02a99d16168a860668ead8ebd8b4cfa7 427 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 125 167 6.3E-11 T 29-03-2018 IPR001330 PFTB repeat GO:0003824 SMALA_RS14780 b399216dad4da18b818621f21b487899 349 Pfam PF09084 NMT1/THI5 like 57 272 1.6E-45 T 29-03-2018 IPR015168 SsuA/THI5-like SMALA_RS14780 b399216dad4da18b818621f21b487899 349 Gene3D G3DSA:3.40.190.10 149 349 5.8E-26 T 29-03-2018 SMALA_RS14780 b399216dad4da18b818621f21b487899 349 Gene3D G3DSA:3.40.190.10 45 148 2.3E-17 T 29-03-2018 SMALA_RS14780 b399216dad4da18b818621f21b487899 349 SUPERFAMILY SSF53850 49 277 1.23E-35 T 29-03-2018 SMALA_RS40230 fec4a6b7b64885ca984919beb9db0f1f 287 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 192 3.6E-4 T 29-03-2018 SMALA_RS40230 fec4a6b7b64885ca984919beb9db0f1f 287 Gene3D G3DSA:3.40.50.720 1 46 8.1E-13 T 29-03-2018 SMALA_RS40230 fec4a6b7b64885ca984919beb9db0f1f 287 Gene3D G3DSA:3.40.50.720 47 234 7.2E-43 T 29-03-2018 SMALA_RS40230 fec4a6b7b64885ca984919beb9db0f1f 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 2.9E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40230 fec4a6b7b64885ca984919beb9db0f1f 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 2.9E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40230 fec4a6b7b64885ca984919beb9db0f1f 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 2.9E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40230 fec4a6b7b64885ca984919beb9db0f1f 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 2.9E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40230 fec4a6b7b64885ca984919beb9db0f1f 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 2.9E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40230 fec4a6b7b64885ca984919beb9db0f1f 287 Pfam PF00106 short chain dehydrogenase 8 201 1.9E-52 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40230 fec4a6b7b64885ca984919beb9db0f1f 287 SUPERFAMILY SSF51735 2 259 3.55E-65 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS40230 fec4a6b7b64885ca984919beb9db0f1f 287 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 2.8E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40230 fec4a6b7b64885ca984919beb9db0f1f 287 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 2.8E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40230 fec4a6b7b64885ca984919beb9db0f1f 287 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 2.8E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS36785 4427b15b29c9f8f2f016474d8c7f2979 402 Pfam PF07282 Putative transposase DNA-binding domain 294 361 4.1E-23 T 29-03-2018 IPR010095 Transposase IS605, OrfB, C-terminal SMALA_RS36785 4427b15b29c9f8f2f016474d8c7f2979 402 Pfam PF12323 Helix-turn-helix domain 1 49 8.0E-22 T 29-03-2018 IPR021027 Transposase, putative, helix-turn-helix domain SMALA_RS36785 4427b15b29c9f8f2f016474d8c7f2979 402 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 249 321 3.6E-19 T 29-03-2018 IPR010095 Transposase IS605, OrfB, C-terminal SMALA_RS36785 4427b15b29c9f8f2f016474d8c7f2979 402 Pfam PF01385 Probable transposase 176 280 3.2E-29 T 29-03-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 SMALA_RS40025 992db043d6351459ab182d2685210173 193 SUPERFAMILY SSF48498 80 191 1.24E-16 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS40025 992db043d6351459ab182d2685210173 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 60 1.1E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS40025 992db043d6351459ab182d2685210173 193 Gene3D G3DSA:1.10.10.60 3 62 1.3E-14 T 29-03-2018 SMALA_RS40025 992db043d6351459ab182d2685210173 193 SUPERFAMILY SSF46689 3 80 9.23E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS40025 992db043d6351459ab182d2685210173 193 Gene3D G3DSA:1.10.357.10 63 193 2.2E-16 T 29-03-2018 SMALA_RS34415 4776af4434885a14111f779443887e1e 230 Gene3D G3DSA:3.30.450.40 3 176 8.8E-22 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS34415 4776af4434885a14111f779443887e1e 230 SMART SM01012 168 223 1.9E-21 T 29-03-2018 IPR005561 ANTAR domain GO:0003723 SMALA_RS34415 4776af4434885a14111f779443887e1e 230 SUPERFAMILY SSF55781 23 175 8.29E-18 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS34415 4776af4434885a14111f779443887e1e 230 PIRSF PIRSF036625 1 230 6.1E-90 T 29-03-2018 IPR012074 GAF-ANTAR transcription anti-termination regulator, putative SMALA_RS34415 4776af4434885a14111f779443887e1e 230 Pfam PF13185 GAF domain 21 163 1.9E-13 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS34415 4776af4434885a14111f779443887e1e 230 Gene3D G3DSA:1.10.10.10 177 225 3.6E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS34415 4776af4434885a14111f779443887e1e 230 SUPERFAMILY SSF52172 164 222 9.44E-11 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS34415 4776af4434885a14111f779443887e1e 230 Pfam PF03861 ANTAR domain 170 222 8.6E-20 T 29-03-2018 IPR005561 ANTAR domain GO:0003723 SMALA_RS10310 d1bb82216604880ced7b0ff3b152144d 518 Pfam PF01593 Flavin containing amine oxidoreductase 14 298 1.1E-18 T 29-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 SMALA_RS10310 d1bb82216604880ced7b0ff3b152144d 518 SUPERFAMILY SSF51905 2 336 1.3E-50 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS10310 d1bb82216604880ced7b0ff3b152144d 518 SUPERFAMILY SSF51905 471 509 1.3E-50 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS10310 d1bb82216604880ced7b0ff3b152144d 518 Gene3D G3DSA:3.50.50.60 2 509 8.6E-30 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS08165 00c7c1208689ca1f87130d958b1aef15 153 Gene3D G3DSA:3.10.129.10 4 153 2.7E-40 T 29-03-2018 SMALA_RS08165 00c7c1208689ca1f87130d958b1aef15 153 SUPERFAMILY SSF54637 11 150 8.51E-41 T 29-03-2018 IPR029069 HotDog domain SMALA_RS08165 00c7c1208689ca1f87130d958b1aef15 153 Pfam PF01575 MaoC like domain 15 134 2.8E-27 T 29-03-2018 IPR002539 MaoC-like domain SMALA_RS08105 d1e155a48e80f7ff257e54248d665ad1 110 Pfam PF02656 Domain of unknown function (DUF202) 14 77 9.1E-8 T 29-03-2018 IPR003807 Domain of unknown function DUF202 SMALA_RS29290 b7c306b2bc8509819f6803cb85ee8d52 698 Pfam PF13520 Amino acid permease 57 464 1.7E-30 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMALA_RS30050 75219bf7b656ed681657160dc6ce0906 715 SUPERFAMILY SSF81296 5 147 1.29E-41 T 29-03-2018 IPR014756 Immunoglobulin E-set SMALA_RS30050 75219bf7b656ed681657160dc6ce0906 715 SMART SM00642 177 558 2.5E-8 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SMALA_RS30050 75219bf7b656ed681657160dc6ce0906 715 Gene3D G3DSA:2.60.40.10 5 136 9.4E-46 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS30050 75219bf7b656ed681657160dc6ce0906 715 Pfam PF00128 Alpha amylase, catalytic domain 189 530 6.7E-9 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SMALA_RS30050 75219bf7b656ed681657160dc6ce0906 715 Gene3D G3DSA:2.60.40.1180 590 715 1.6E-31 T 29-03-2018 SMALA_RS30050 75219bf7b656ed681657160dc6ce0906 715 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 10 96 3.5E-15 T 29-03-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077 SMALA_RS30050 75219bf7b656ed681657160dc6ce0906 715 SUPERFAMILY SSF51011 600 712 7.19E-24 T 29-03-2018 SMALA_RS30050 75219bf7b656ed681657160dc6ce0906 715 TIGRFAM TIGR02100 glgX_debranch: glycogen debranching enzyme GlgX 6 712 5.8E-296 T 29-03-2018 IPR011837 Glycogen debranching enzyme, GlgX type GO:0004133|GO:0004553|GO:0005980 SMALA_RS30050 75219bf7b656ed681657160dc6ce0906 715 SUPERFAMILY SSF51445 499 585 1.21E-130 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS30050 75219bf7b656ed681657160dc6ce0906 715 SUPERFAMILY SSF51445 133 470 1.21E-130 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS30050 75219bf7b656ed681657160dc6ce0906 715 Gene3D G3DSA:3.20.20.80 137 589 1.7E-110 T 29-03-2018 SMALA_RS06190 678fa9c7a695bef170263489d55360b5 453 SUPERFAMILY SSF55874 274 414 4.73E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS06190 678fa9c7a695bef170263489d55360b5 453 Pfam PF07730 Histidine kinase 190 255 9.5E-17 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMALA_RS06190 678fa9c7a695bef170263489d55360b5 453 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 304 415 2.5E-6 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS06190 678fa9c7a695bef170263489d55360b5 453 Gene3D G3DSA:3.30.565.10 269 416 1.9E-23 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS23110 c2bdb60428ff71b62c07039d450302b7 488 SUPERFAMILY SSF56645 1 119 2.17E-28 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMALA_RS23110 c2bdb60428ff71b62c07039d450302b7 488 SUPERFAMILY SSF56645 149 252 2.17E-28 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMALA_RS23110 c2bdb60428ff71b62c07039d450302b7 488 SUPERFAMILY SSF47203 276 415 2.74E-30 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMALA_RS23110 c2bdb60428ff71b62c07039d450302b7 488 Gene3D G3DSA:2.40.110.10 152 252 3.0E-6 T 29-03-2018 SMALA_RS23110 c2bdb60428ff71b62c07039d450302b7 488 Gene3D G3DSA:1.10.540.10 1 125 1.3E-25 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS23110 c2bdb60428ff71b62c07039d450302b7 488 Gene3D G3DSA:1.20.140.10 261 417 3.9E-32 T 29-03-2018 SMALA_RS23110 c2bdb60428ff71b62c07039d450302b7 488 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 279 416 1.8E-21 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMALA_RS23110 c2bdb60428ff71b62c07039d450302b7 488 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 118 1.1E-20 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS19495 47cc8e14bdf5f102eff824f54ff0c6b6 177 SUPERFAMILY SSF55811 2 130 2.98E-16 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMALA_RS19495 47cc8e14bdf5f102eff824f54ff0c6b6 177 Pfam PF00293 NUDIX domain 9 85 2.0E-11 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SMALA_RS19495 47cc8e14bdf5f102eff824f54ff0c6b6 177 Gene3D G3DSA:3.90.79.10 2 155 1.6E-16 T 29-03-2018 SMALA_RS12105 f6f5886a3a4b547bce561ae662e1378d 520 SUPERFAMILY SSF52540 3 229 9.4E-54 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS12105 f6f5886a3a4b547bce561ae662e1378d 520 SUPERFAMILY SSF52540 269 505 9.1E-43 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS12105 f6f5886a3a4b547bce561ae662e1378d 520 Pfam PF00005 ABC transporter 20 171 2.5E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS12105 f6f5886a3a4b547bce561ae662e1378d 520 Pfam PF00005 ABC transporter 289 444 6.8E-17 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS12105 f6f5886a3a4b547bce561ae662e1378d 520 ProSitePatterns PS00211 ABC transporters family signature. 417 431 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS12105 f6f5886a3a4b547bce561ae662e1378d 520 Gene3D G3DSA:3.40.50.300 1 239 1.1E-49 T 29-03-2018 SMALA_RS12105 f6f5886a3a4b547bce561ae662e1378d 520 SMART SM00382 297 500 3.5E-4 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS12105 f6f5886a3a4b547bce561ae662e1378d 520 SMART SM00382 29 219 1.2E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS12105 f6f5886a3a4b547bce561ae662e1378d 520 Gene3D G3DSA:3.40.50.300 253 511 8.3E-37 T 29-03-2018 SMALA_RS23140 6a98309dffa86957a63416bad91bcd10 184 Gene3D G3DSA:3.40.190.10 1 166 6.8E-4 T 29-03-2018 SMALA_RS18260 460923cc0912332c514fb69087dd6484 115 Pfam PF00072 Response regulator receiver domain 4 89 2.0E-6 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS18260 460923cc0912332c514fb69087dd6484 115 SUPERFAMILY SSF52172 1 89 1.2E-12 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS18260 460923cc0912332c514fb69087dd6484 115 Gene3D G3DSA:3.40.50.2300 2 112 1.2E-12 T 29-03-2018 SMALA_RS06320 08d8741b2bd5a20e3141ba85b6fbd582 525 Gene3D G3DSA:3.30.300.30 424 524 7.7E-22 T 29-03-2018 SMALA_RS06320 08d8741b2bd5a20e3141ba85b6fbd582 525 Pfam PF13193 AMP-binding enzyme C-terminal domain 437 511 3.2E-13 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS06320 08d8741b2bd5a20e3141ba85b6fbd582 525 Gene3D G3DSA:3.40.50.980 187 343 5.9E-30 T 29-03-2018 SMALA_RS06320 08d8741b2bd5a20e3141ba85b6fbd582 525 Pfam PF00501 AMP-binding enzyme 14 426 9.8E-61 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS06320 08d8741b2bd5a20e3141ba85b6fbd582 525 ProSitePatterns PS00455 Putative AMP-binding domain signature. 182 193 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS06320 08d8741b2bd5a20e3141ba85b6fbd582 525 Gene3D G3DSA:3.40.50.980 5 186 1.1E-21 T 29-03-2018 SMALA_RS06320 08d8741b2bd5a20e3141ba85b6fbd582 525 Gene3D G3DSA:2.30.38.10 348 421 1.8E-21 T 29-03-2018 SMALA_RS06320 08d8741b2bd5a20e3141ba85b6fbd582 525 SUPERFAMILY SSF56801 10 520 6.02E-105 T 29-03-2018 SMALA_RS14510 eda48a00e67337cb0d076da083968926 235 Pfam PF00106 short chain dehydrogenase 10 197 1.5E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS14510 eda48a00e67337cb0d076da083968926 235 Gene3D G3DSA:3.40.50.720 149 234 3.6E-12 T 29-03-2018 SMALA_RS14510 eda48a00e67337cb0d076da083968926 235 SUPERFAMILY SSF51735 4 233 5.01E-49 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS14510 eda48a00e67337cb0d076da083968926 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 185 202 2.4E-16 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS14510 eda48a00e67337cb0d076da083968926 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 183 2.4E-16 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS14510 eda48a00e67337cb0d076da083968926 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 2.4E-16 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS14510 eda48a00e67337cb0d076da083968926 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 138 154 2.4E-16 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS14510 eda48a00e67337cb0d076da083968926 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 2.4E-16 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS14510 eda48a00e67337cb0d076da083968926 235 Gene3D G3DSA:3.40.50.720 3 148 8.0E-26 T 29-03-2018 SMALA_RS05165 dc53cdfb5c21aee2dd825a4ce17319e7 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 6.9E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS05165 dc53cdfb5c21aee2dd825a4ce17319e7 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 6.9E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS05165 dc53cdfb5c21aee2dd825a4ce17319e7 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 139 6.9E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS05165 dc53cdfb5c21aee2dd825a4ce17319e7 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 6.9E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS05165 dc53cdfb5c21aee2dd825a4ce17319e7 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 6.9E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS05165 dc53cdfb5c21aee2dd825a4ce17319e7 293 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 2.7E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS05165 dc53cdfb5c21aee2dd825a4ce17319e7 293 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 129 137 2.7E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS05165 dc53cdfb5c21aee2dd825a4ce17319e7 293 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 2.7E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS05165 dc53cdfb5c21aee2dd825a4ce17319e7 293 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4 190 6.1E-5 T 29-03-2018 SMALA_RS05165 dc53cdfb5c21aee2dd825a4ce17319e7 293 SUPERFAMILY SSF51735 2 242 3.56E-65 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS05165 dc53cdfb5c21aee2dd825a4ce17319e7 293 Pfam PF00106 short chain dehydrogenase 5 189 5.2E-51 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS05165 dc53cdfb5c21aee2dd825a4ce17319e7 293 Gene3D G3DSA:3.40.50.720 1 279 1.6E-68 T 29-03-2018 SMALA_RS33205 8a70bf358e6e68a727e109feeeab9693 400 Gene3D G3DSA:3.50.50.60 1 399 5.9E-43 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS33205 8a70bf358e6e68a727e109feeeab9693 400 Pfam PF01494 FAD binding domain 297 328 1.9E-6 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 SMALA_RS33205 8a70bf358e6e68a727e109feeeab9693 400 Pfam PF01494 FAD binding domain 8 193 3.0E-11 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 SMALA_RS33205 8a70bf358e6e68a727e109feeeab9693 400 SUPERFAMILY SSF51905 7 172 7.61E-48 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS33205 8a70bf358e6e68a727e109feeeab9693 400 SUPERFAMILY SSF51905 281 367 7.61E-48 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS33205 8a70bf358e6e68a727e109feeeab9693 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 2.2E-20 T 29-03-2018 SMALA_RS33205 8a70bf358e6e68a727e109feeeab9693 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 309 325 2.2E-20 T 29-03-2018 SMALA_RS33205 8a70bf358e6e68a727e109feeeab9693 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 151 166 2.2E-20 T 29-03-2018 SMALA_RS33205 8a70bf358e6e68a727e109feeeab9693 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 294 309 2.2E-20 T 29-03-2018 SMALA_RS18180 14d5a21343eee0fa1fd81850a0bbf579 349 Gene3D G3DSA:3.40.50.300 4 348 2.6E-65 T 29-03-2018 SMALA_RS18180 14d5a21343eee0fa1fd81850a0bbf579 349 Pfam PF13732 Domain of unknown function (DUF4162) 220 311 2.6E-7 T 29-03-2018 IPR025302 Domain of unknown function DUF4162 SMALA_RS18180 14d5a21343eee0fa1fd81850a0bbf579 349 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS18180 14d5a21343eee0fa1fd81850a0bbf579 349 SMART SM00382 32 215 2.6E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS18180 14d5a21343eee0fa1fd81850a0bbf579 349 SUPERFAMILY SSF52540 7 228 1.09E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS18180 14d5a21343eee0fa1fd81850a0bbf579 349 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 15 313 2.6E-106 T 29-03-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 SMALA_RS18180 14d5a21343eee0fa1fd81850a0bbf579 349 Pfam PF00005 ABC transporter 24 166 1.5E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS13340 c93ab8181582e1f82292fca8baf079cc 197 PIRSF PIRSF016661 13 196 1.5E-38 T 29-03-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 SMALA_RS13340 c93ab8181582e1f82292fca8baf079cc 197 Pfam PF02632 BioY family 52 191 8.9E-33 T 29-03-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 SMALA_RS08765 4c9d9629ac329c2b3964d89339b4ddf0 115 SUPERFAMILY SSF55718 6 115 1.06E-12 T 29-03-2018 IPR003033 SCP2 sterol-binding domain SMALA_RS08765 4c9d9629ac329c2b3964d89339b4ddf0 115 Gene3D G3DSA:3.30.1050.10 1 115 3.6E-14 T 29-03-2018 IPR003033 SCP2 sterol-binding domain SMALA_RS35755 de8879d8b4c7d0d4b5be53ec6c40bc01 421 Pfam PF00534 Glycosyl transferases group 1 197 353 6.1E-36 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 SMALA_RS35755 de8879d8b4c7d0d4b5be53ec6c40bc01 421 Gene3D G3DSA:3.40.50.2000 173 358 9.9E-42 T 29-03-2018 SMALA_RS35755 de8879d8b4c7d0d4b5be53ec6c40bc01 421 SUPERFAMILY SSF53756 2 376 2.43E-66 T 29-03-2018 SMALA_RS16260 4c61c2810e490a13e47e3dbcc4dff17e 457 Pfam PF01212 Beta-eliminating lyase 42 418 1.1E-73 T 29-03-2018 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 SMALA_RS16260 4c61c2810e490a13e47e3dbcc4dff17e 457 PIRSF PIRSF001386 1 454 1.5E-175 T 29-03-2018 IPR011166 Beta-eliminating lyase family GO:0009072|GO:0016830 KEGG: 00380+4.1.99.1 SMALA_RS16260 4c61c2810e490a13e47e3dbcc4dff17e 457 Gene3D G3DSA:3.90.226.10 102 212 8.6E-4 T 29-03-2018 SMALA_RS16260 4c61c2810e490a13e47e3dbcc4dff17e 457 SUPERFAMILY SSF53383 2 453 1.75E-107 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS16260 4c61c2810e490a13e47e3dbcc4dff17e 457 Gene3D G3DSA:3.90.1150.10 268 451 1.2E-63 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS16260 4c61c2810e490a13e47e3dbcc4dff17e 457 Gene3D G3DSA:3.90.1150.10 13 101 1.6E-23 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS27605 a6ed21758b9600af1463f61a9957cea7 303 SUPERFAMILY SSF51679 12 294 8.11E-58 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS27605 a6ed21758b9600af1463f61a9957cea7 303 TIGRFAM TIGR03619 F420_Rv2161c: probable F420-dependent oxidoreductase, Rv2161c family 22 278 4.0E-62 T 29-03-2018 IPR019921 Luciferase-like, F420-dependent oxidoreductase, Rv2161c, predicted SMALA_RS27605 a6ed21758b9600af1463f61a9957cea7 303 Gene3D G3DSA:3.20.20.30 1 302 5.7E-64 T 29-03-2018 SMALA_RS27605 a6ed21758b9600af1463f61a9957cea7 303 Pfam PF00296 Luciferase-like monooxygenase 15 259 6.3E-50 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS34220 d3b8c222889c37ff03381fb76aad58e4 278 Pfam PF03537 Glycoside-hydrolase family GH114 46 266 2.7E-45 T 29-03-2018 IPR004352 Glycoside-hydrolase family GH114, TIM-barrel domain SMALA_RS34220 d3b8c222889c37ff03381fb76aad58e4 278 Gene3D G3DSA:3.20.20.70 53 261 2.9E-25 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS34220 d3b8c222889c37ff03381fb76aad58e4 278 SUPERFAMILY SSF51445 46 251 2.95E-14 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS21310 faac66732d00746086d4a56695e82de4 538 Gene3D G3DSA:3.30.43.10 77 156 1.2E-20 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 SMALA_RS21310 faac66732d00746086d4a56695e82de4 538 SUPERFAMILY SSF56176 75 267 3.55E-49 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SMALA_RS21310 faac66732d00746086d4a56695e82de4 538 Pfam PF01565 FAD binding domain 103 236 1.6E-27 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 SMALA_RS21310 faac66732d00746086d4a56695e82de4 538 Pfam PF08031 Berberine and berberine like 495 537 2.3E-12 T 29-03-2018 IPR012951 Berberine/berberine-like GO:0016491|GO:0050660|GO:0055114 SMALA_RS21310 faac66732d00746086d4a56695e82de4 538 Gene3D G3DSA:3.30.465.10 157 294 3.0E-35 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SMALA_RS20195 9a2e3af22c55510d4a37d657f849379a 404 SUPERFAMILY SSF48230 286 347 9.15E-48 T 29-03-2018 IPR008929 Chondroitin AC/alginate lyase Reactome: R-HSA-2022923 SMALA_RS20195 9a2e3af22c55510d4a37d657f849379a 404 SUPERFAMILY SSF48230 45 256 9.15E-48 T 29-03-2018 IPR008929 Chondroitin AC/alginate lyase Reactome: R-HSA-2022923 SMALA_RS20195 9a2e3af22c55510d4a37d657f849379a 404 Pfam PF05426 Alginate lyase 113 332 6.3E-14 T 29-03-2018 IPR008397 Alginate lyase domain GO:0016829|GO:0042597 KEGG: 00051+4.2.2.3|MetaCyc: PWY-6986 SMALA_RS20195 9a2e3af22c55510d4a37d657f849379a 404 Gene3D G3DSA:1.50.10.100 27 395 6.7E-71 T 29-03-2018 SMALA_RS30115 72d1accc12f6b4013f1486fcf229dad4 283 Gene3D G3DSA:1.10.260.40 4 86 5.4E-17 T 29-03-2018 SMALA_RS30115 72d1accc12f6b4013f1486fcf229dad4 283 SMART SM00530 19 74 1.5E-9 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS30115 72d1accc12f6b4013f1486fcf229dad4 283 SUPERFAMILY SSF47413 13 70 9.01E-11 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS30115 72d1accc12f6b4013f1486fcf229dad4 283 Pfam PF13560 Helix-turn-helix domain 15 75 4.7E-16 T 29-03-2018 SMALA_RS25505 593d13b283ae72f1783b434aec6e1283 476 SUPERFAMILY SSF63737 50 241 2.62E-37 T 29-03-2018 SMALA_RS25505 593d13b283ae72f1783b434aec6e1283 476 Gene3D G3DSA:2.60.40.1730 58 243 8.1E-45 T 29-03-2018 SMALA_RS25505 593d13b283ae72f1783b434aec6e1283 476 Pfam PF01433 Peptidase family M1 domain 322 466 2.2E-30 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMALA_RS25505 593d13b283ae72f1783b434aec6e1283 476 SUPERFAMILY SSF55486 249 473 5.27E-51 T 29-03-2018 SMALA_RS25505 593d13b283ae72f1783b434aec6e1283 476 Gene3D G3DSA:1.10.390.10 322 470 6.0E-38 T 29-03-2018 SMALA_RS25505 593d13b283ae72f1783b434aec6e1283 476 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 178 193 6.3E-11 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMALA_RS25505 593d13b283ae72f1783b434aec6e1283 476 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 324 339 6.3E-11 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMALA_RS25505 593d13b283ae72f1783b434aec6e1283 476 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 225 240 6.3E-11 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMALA_RS25505 593d13b283ae72f1783b434aec6e1283 476 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 343 355 6.3E-11 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMALA_RS26010 6405e893b28c9be971d476d94c4bafb2 311 Pfam PF09296 NADH pyrophosphatase-like rudimentary NUDIX domain 43 137 1.1E-12 T 29-03-2018 IPR015375 NADH pyrophosphatase-like, N-terminal GO:0016787 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381|MetaCyc: PWY-7761 SMALA_RS26010 6405e893b28c9be971d476d94c4bafb2 311 Pfam PF00293 NUDIX domain 174 286 2.1E-19 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SMALA_RS26010 6405e893b28c9be971d476d94c4bafb2 311 Gene3D G3DSA:3.90.79.10 172 307 3.6E-36 T 29-03-2018 SMALA_RS26010 6405e893b28c9be971d476d94c4bafb2 311 SUPERFAMILY SSF55811 123 306 7.45E-48 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMALA_RS26010 6405e893b28c9be971d476d94c4bafb2 311 ProSitePatterns PS00893 Nudix box signature. 206 227 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 SMALA_RS26010 6405e893b28c9be971d476d94c4bafb2 311 Pfam PF09297 NADH pyrophosphatase zinc ribbon domain 140 170 8.0E-14 T 29-03-2018 IPR015376 Zinc ribbon, NADH pyrophosphatase GO:0016787|GO:0046872 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381|MetaCyc: PWY-7761 SMALA_RS10010 9af7c88394a228a50c2b6c17800cb407 276 Gene3D G3DSA:3.20.20.70 52 260 3.1E-33 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS10010 9af7c88394a228a50c2b6c17800cb407 276 Pfam PF03537 Glycoside-hydrolase family GH114 51 263 4.4E-51 T 29-03-2018 IPR004352 Glycoside-hydrolase family GH114, TIM-barrel domain SMALA_RS10010 9af7c88394a228a50c2b6c17800cb407 276 SUPERFAMILY SSF51445 51 247 5.9E-20 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS31680 5e4ef9aaf56674b184e103bb3be6bbbe 682 Pfam PF02779 Transketolase, pyrimidine binding domain 367 538 5.2E-39 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain SMALA_RS31680 5e4ef9aaf56674b184e103bb3be6bbbe 682 ProSitePatterns PS00801 Transketolase signature 1. 13 33 - T 29-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SMALA_RS31680 5e4ef9aaf56674b184e103bb3be6bbbe 682 ProSitePatterns PS00802 Transketolase signature 2. 481 497 - T 29-03-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SMALA_RS31680 5e4ef9aaf56674b184e103bb3be6bbbe 682 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 6 350 8.8E-126 T 29-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SMALA_RS31680 5e4ef9aaf56674b184e103bb3be6bbbe 682 TIGRFAM TIGR00232 tktlase_bact: transketolase 8 679 9.9E-239 T 29-03-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 SMALA_RS31680 5e4ef9aaf56674b184e103bb3be6bbbe 682 SUPERFAMILY SSF52518 353 541 1.09E-60 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold SMALA_RS31680 5e4ef9aaf56674b184e103bb3be6bbbe 682 Gene3D G3DSA:3.40.50.970 2 374 3.9E-91 T 29-03-2018 SMALA_RS31680 5e4ef9aaf56674b184e103bb3be6bbbe 682 SUPERFAMILY SSF52518 4 337 2.95E-103 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold SMALA_RS31680 5e4ef9aaf56674b184e103bb3be6bbbe 682 SUPERFAMILY SSF52922 549 680 5.76E-43 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMALA_RS31680 5e4ef9aaf56674b184e103bb3be6bbbe 682 Gene3D G3DSA:3.40.50.970 375 555 2.5E-39 T 29-03-2018 SMALA_RS31680 5e4ef9aaf56674b184e103bb3be6bbbe 682 Pfam PF02780 Transketolase, C-terminal domain 560 671 3.6E-12 T 29-03-2018 IPR033248 Transketolase, C-terminal domain SMALA_RS31680 5e4ef9aaf56674b184e103bb3be6bbbe 682 SMART SM00861 367 539 1.9E-58 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain SMALA_RS31680 5e4ef9aaf56674b184e103bb3be6bbbe 682 Gene3D G3DSA:3.40.50.920 556 678 5.4E-33 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMALA_RS34665 8e21bf45e18eb4233d8a4ccd2c59b56e 188 SMART SM00987 23 178 6.2E-9 T 29-03-2018 SMALA_RS34665 8e21bf45e18eb4233d8a4ccd2c59b56e 188 SMART SM00986 23 178 6.2E-9 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SMALA_RS34665 8e21bf45e18eb4233d8a4ccd2c59b56e 188 Gene3D G3DSA:3.40.470.10 24 187 6.5E-52 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SMALA_RS34665 8e21bf45e18eb4233d8a4ccd2c59b56e 188 SUPERFAMILY SSF52141 22 181 8.72E-46 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SMALA_RS34665 8e21bf45e18eb4233d8a4ccd2c59b56e 188 Pfam PF03167 Uracil DNA glycosylase superfamily 24 174 2.1E-26 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SMALA_RS19010 f67e7aadff517badee47c4b7f359b182 234 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 115 205 1.6E-15 T 29-03-2018 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain SMALA_RS15380 a3b551ffe4b3cd7f5dc11b07b97db823 829 Gene3D G3DSA:3.40.50.300 669 827 9.1E-14 T 29-03-2018 SMALA_RS15380 a3b551ffe4b3cd7f5dc11b07b97db823 829 Pfam PF13538 UvrD-like helicase C-terminal domain 766 808 2.6E-8 T 29-03-2018 IPR027785 UvrD-like helicase C-terminal domain SMALA_RS15380 a3b551ffe4b3cd7f5dc11b07b97db823 829 Pfam PF00580 UvrD/REP helicase N-terminal domain 595 643 1.7E-6 T 29-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 SMALA_RS15380 a3b551ffe4b3cd7f5dc11b07b97db823 829 SUPERFAMILY SSF52540 431 505 1.63E-47 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS15380 a3b551ffe4b3cd7f5dc11b07b97db823 829 SUPERFAMILY SSF52540 207 285 1.63E-47 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS15380 a3b551ffe4b3cd7f5dc11b07b97db823 829 SUPERFAMILY SSF52540 584 816 1.63E-47 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS15380 a3b551ffe4b3cd7f5dc11b07b97db823 829 Gene3D G3DSA:3.40.50.300 213 647 5.7E-30 T 29-03-2018 SMALA_RS12290 061aeb6c5f7e0bdac0d590965b51598d 308 Gene3D G3DSA:3.30.565.10 184 308 2.0E-25 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS12290 061aeb6c5f7e0bdac0d590965b51598d 308 Pfam PF00672 HAMP domain 45 97 2.0E-6 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMALA_RS12290 061aeb6c5f7e0bdac0d590965b51598d 308 Gene3D G3DSA:3.90.226.10 46 183 0.0016 T 29-03-2018 SMALA_RS12290 061aeb6c5f7e0bdac0d590965b51598d 308 SUPERFAMILY SSF55874 194 302 1.44E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS12290 061aeb6c5f7e0bdac0d590965b51598d 308 SMART SM00304 45 100 6.6E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMALA_RS12290 061aeb6c5f7e0bdac0d590965b51598d 308 Pfam PF07730 Histidine kinase 113 177 1.7E-18 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMALA_RS12290 061aeb6c5f7e0bdac0d590965b51598d 308 SMART SM00387 215 305 0.0044 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS12400 666fbdb349cfeb4033f377342551f8c9 107 Pfam PF03091 CutA1 divalent ion tolerance protein 6 102 5.5E-36 T 29-03-2018 IPR004323 Divalent ion tolerance protein, CutA GO:0010038 SMALA_RS12400 666fbdb349cfeb4033f377342551f8c9 107 SUPERFAMILY SSF54913 3 104 3.04E-36 T 29-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta SMALA_RS12400 666fbdb349cfeb4033f377342551f8c9 107 Gene3D G3DSA:3.30.70.120 2 106 1.8E-37 T 29-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal SMALA_RS16115 dbb62b3de059d6c56da409c27888c03b 207 Gene3D G3DSA:3.20.20.120 8 145 0.001 T 29-03-2018 IPR029065 Enolase C-terminal domain-like SMALA_RS42500 a7f24f1ba1f435257826b06ecaff00f1 415 SUPERFAMILY SSF51679 1 398 2.06E-101 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS42500 a7f24f1ba1f435257826b06ecaff00f1 415 Pfam PF00296 Luciferase-like monooxygenase 21 348 2.0E-47 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS42500 a7f24f1ba1f435257826b06ecaff00f1 415 PIRSF PIRSF000337 1 168 1.8E-49 T 29-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 SMALA_RS42500 a7f24f1ba1f435257826b06ecaff00f1 415 PIRSF PIRSF000337 163 405 4.4E-68 T 29-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 SMALA_RS42500 a7f24f1ba1f435257826b06ecaff00f1 415 Gene3D G3DSA:3.20.20.30 1 412 4.7E-83 T 29-03-2018 SMALA_RS12220 ce93303a16cd0b09334b8771f9968e03 743 Gene3D G3DSA:3.90.1170.50 22 152 3.0E-32 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMALA_RS12220 ce93303a16cd0b09334b8771f9968e03 743 Gene3D G3DSA:3.30.365.10 591 726 4.7E-45 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMALA_RS12220 ce93303a16cd0b09334b8771f9968e03 743 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 584 668 5.7E-22 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMALA_RS12220 ce93303a16cd0b09334b8771f9968e03 743 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 187 559 6.0E-84 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMALA_RS12220 ce93303a16cd0b09334b8771f9968e03 743 SUPERFAMILY SSF56003 157 725 1.01E-148 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMALA_RS12220 ce93303a16cd0b09334b8771f9968e03 743 SUPERFAMILY SSF54665 38 170 1.31E-33 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMALA_RS12220 ce93303a16cd0b09334b8771f9968e03 743 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 55 164 2.0E-21 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMALA_RS12220 ce93303a16cd0b09334b8771f9968e03 743 Gene3D G3DSA:3.30.365.10 470 590 5.5E-23 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMALA_RS12220 ce93303a16cd0b09334b8771f9968e03 743 SMART SM01008 54 164 1.0E-31 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMALA_RS12220 ce93303a16cd0b09334b8771f9968e03 743 Gene3D G3DSA:3.30.365.10 277 445 3.5E-34 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMALA_RS12220 ce93303a16cd0b09334b8771f9968e03 743 Gene3D G3DSA:3.30.365.10 153 276 8.6E-27 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMALA_RS10340 52c3bb991c2d05813d489e686cb94e30 395 TIGRFAM TIGR02352 thiamin_ThiO: glycine oxidase ThiO 1 353 2.1E-119 T 29-03-2018 IPR012727 Glycine oxidase ThiO GO:0016491|GO:0050660 SMALA_RS10340 52c3bb991c2d05813d489e686cb94e30 395 SUPERFAMILY SSF54373 217 309 2.35E-21 T 29-03-2018 SMALA_RS10340 52c3bb991c2d05813d489e686cb94e30 395 Gene3D G3DSA:3.30.9.10 98 156 4.1E-12 T 29-03-2018 SMALA_RS10340 52c3bb991c2d05813d489e686cb94e30 395 Gene3D G3DSA:3.30.9.10 157 309 1.6E-29 T 29-03-2018 SMALA_RS10340 52c3bb991c2d05813d489e686cb94e30 395 SUPERFAMILY SSF51905 1 216 1.04E-47 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS10340 52c3bb991c2d05813d489e686cb94e30 395 SUPERFAMILY SSF51905 311 368 1.04E-47 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS10340 52c3bb991c2d05813d489e686cb94e30 395 Pfam PF01266 FAD dependent oxidoreductase 1 348 1.5E-65 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 SMALA_RS10340 52c3bb991c2d05813d489e686cb94e30 395 Gene3D G3DSA:3.40.50.720 1 97 3.7E-4 T 29-03-2018 SMALA_RS03660 eb919f9319bebfb45a09d75cc880e442 610 SUPERFAMILY SSF56801 18 295 3.53E-109 T 29-03-2018 SMALA_RS03660 eb919f9319bebfb45a09d75cc880e442 610 SUPERFAMILY SSF56801 349 608 3.53E-109 T 29-03-2018 SMALA_RS03660 eb919f9319bebfb45a09d75cc880e442 610 Gene3D G3DSA:3.40.50.980 191 399 1.0E-37 T 29-03-2018 SMALA_RS03660 eb919f9319bebfb45a09d75cc880e442 610 Pfam PF00501 AMP-binding enzyme 26 478 4.8E-88 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS03660 eb919f9319bebfb45a09d75cc880e442 610 Gene3D G3DSA:3.30.300.30 473 610 5.7E-16 T 29-03-2018 SMALA_RS03660 eb919f9319bebfb45a09d75cc880e442 610 Gene3D G3DSA:2.30.38.10 400 471 5.6E-21 T 29-03-2018 SMALA_RS03660 eb919f9319bebfb45a09d75cc880e442 610 Gene3D G3DSA:3.40.50.980 17 190 2.1E-30 T 29-03-2018 SMALA_RS41595 d03067bce32f92eb5f9870adca16efab 372 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 148 163 1.3E-20 T 29-03-2018 SMALA_RS41595 d03067bce32f92eb5f9870adca16efab 372 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 277 292 1.3E-20 T 29-03-2018 SMALA_RS41595 d03067bce32f92eb5f9870adca16efab 372 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 292 308 1.3E-20 T 29-03-2018 SMALA_RS41595 d03067bce32f92eb5f9870adca16efab 372 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 1.3E-20 T 29-03-2018 SMALA_RS41595 d03067bce32f92eb5f9870adca16efab 372 Gene3D G3DSA:3.50.50.60 1 345 2.8E-53 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS41595 d03067bce32f92eb5f9870adca16efab 372 Pfam PF01494 FAD binding domain 2 337 1.2E-36 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 SMALA_RS41595 d03067bce32f92eb5f9870adca16efab 372 SUPERFAMILY SSF51905 2 169 5.37E-62 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS41595 d03067bce32f92eb5f9870adca16efab 372 SUPERFAMILY SSF51905 264 355 5.37E-62 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS01650 f5dfacd241ead38a747153fddda0db8b 171 SUPERFAMILY SSF55729 1 139 1.72E-24 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS01650 f5dfacd241ead38a747153fddda0db8b 171 PIRSF PIRSF037663 4 168 2.1E-56 T 29-03-2018 IPR017255 Acetyltransferase, GNAT, predicted SMALA_RS01650 f5dfacd241ead38a747153fddda0db8b 171 Gene3D G3DSA:3.40.630.30 3 166 2.4E-26 T 29-03-2018 SMALA_RS01650 f5dfacd241ead38a747153fddda0db8b 171 Pfam PF00583 Acetyltransferase (GNAT) family 20 134 3.5E-14 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SMALA_RS03095 b6a3b89feea1eced4aab1a193cb58d40 560 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 48 517 16.294 T 29-03-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 SMALA_RS03095 b6a3b89feea1eced4aab1a193cb58d40 560 Pfam PF00795 Carbon-nitrogen hydrolase 257 483 7.9E-22 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMALA_RS03095 b6a3b89feea1eced4aab1a193cb58d40 560 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 103 478 2.6E-90 T 29-03-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 SMALA_RS03095 b6a3b89feea1eced4aab1a193cb58d40 560 Gene3D G3DSA:3.60.110.10 247 503 5.9E-41 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMALA_RS03095 b6a3b89feea1eced4aab1a193cb58d40 560 SUPERFAMILY SSF56317 251 512 6.02E-42 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMALA_RS36045 05455990230052efbde7bdd0292befff 288 SMART SM01232 138 230 1.2E-31 T 29-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 SMALA_RS36045 05455990230052efbde7bdd0292befff 288 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 138 222 2.1E-20 T 29-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 SMALA_RS36045 05455990230052efbde7bdd0292befff 288 SUPERFAMILY SSF81624 2 147 4.45E-24 T 29-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 SMALA_RS36045 05455990230052efbde7bdd0292befff 288 SUPERFAMILY SSF57716 227 273 2.4E-11 T 29-03-2018 SMALA_RS36045 05455990230052efbde7bdd0292befff 288 SMART SM00898 2 124 2.1E-22 T 29-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 SMALA_RS36045 05455990230052efbde7bdd0292befff 288 Pfam PF06827 Zinc finger found in FPG and IleRS 245 272 3.5E-6 T 29-03-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 SMALA_RS36045 05455990230052efbde7bdd0292befff 288 Gene3D G3DSA:3.20.190.10 1 132 3.4E-26 T 29-03-2018 SMALA_RS36045 05455990230052efbde7bdd0292befff 288 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 89 1.2E-15 T 29-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 SMALA_RS36045 05455990230052efbde7bdd0292befff 288 SUPERFAMILY SSF46946 137 220 1.41E-23 T 29-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 SMALA_RS36045 05455990230052efbde7bdd0292befff 288 Gene3D G3DSA:1.10.8.50 133 273 6.0E-39 T 29-03-2018 SMALA_RS39065 afa184f6adf754f2c2ecb0b41f48f72d 390 SUPERFAMILY SSF56645 20 214 1.44E-30 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMALA_RS39065 afa184f6adf754f2c2ecb0b41f48f72d 390 Gene3D G3DSA:1.10.540.10 14 109 2.8E-9 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS39065 afa184f6adf754f2c2ecb0b41f48f72d 390 Gene3D G3DSA:1.20.140.10 206 389 5.3E-19 T 29-03-2018 SMALA_RS39065 afa184f6adf754f2c2ecb0b41f48f72d 390 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 237 369 6.2E-36 T 29-03-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain SMALA_RS39065 afa184f6adf754f2c2ecb0b41f48f72d 390 PIRSF PIRSF016578 3 390 9.3E-109 T 29-03-2018 SMALA_RS39065 afa184f6adf754f2c2ecb0b41f48f72d 390 SUPERFAMILY SSF47203 227 384 4.99E-18 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMALA_RS39065 afa184f6adf754f2c2ecb0b41f48f72d 390 Gene3D G3DSA:2.40.110.10 117 205 1.0E-18 T 29-03-2018 SMALA_RS41915 535a856344732301d398e52d54ffa617 274 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 95 269 1.2E-24 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS41915 535a856344732301d398e52d54ffa617 274 Gene3D G3DSA:1.10.3720.10 6 267 5.5E-37 T 29-03-2018 SMALA_RS41915 535a856344732301d398e52d54ffa617 274 SUPERFAMILY SSF161098 73 260 1.57E-22 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS17300 909f57a178ccafe39bf905e4062a8b02 331 SUPERFAMILY SSF51430 1 321 3.67E-97 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS17300 909f57a178ccafe39bf905e4062a8b02 331 Pfam PF00248 Aldo/keto reductase family 15 318 1.6E-69 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS17300 909f57a178ccafe39bf905e4062a8b02 331 Gene3D G3DSA:3.20.20.100 3 320 2.8E-90 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS07350 9cb5f2a4730485884496490188aca11b 567 SUPERFAMILY SSF52540 8 258 2.87E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS07350 9cb5f2a4730485884496490188aca11b 567 ProSitePatterns PS00211 ABC transporters family signature. 452 466 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS07350 9cb5f2a4730485884496490188aca11b 567 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 238 281 1.9E-7 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMALA_RS07350 9cb5f2a4730485884496490188aca11b 567 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 531 557 4.1E-5 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMALA_RS07350 9cb5f2a4730485884496490188aca11b 567 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS07350 9cb5f2a4730485884496490188aca11b 567 SMART SM00382 37 236 1.0E-19 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS07350 9cb5f2a4730485884496490188aca11b 567 SMART SM00382 337 529 1.9E-18 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS07350 9cb5f2a4730485884496490188aca11b 567 SUPERFAMILY SSF52540 310 550 2.51E-71 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS07350 9cb5f2a4730485884496490188aca11b 567 Gene3D G3DSA:3.40.50.300 5 289 4.2E-71 T 29-03-2018 SMALA_RS07350 9cb5f2a4730485884496490188aca11b 567 Gene3D G3DSA:3.40.50.300 304 566 1.0E-72 T 29-03-2018 SMALA_RS07350 9cb5f2a4730485884496490188aca11b 567 Pfam PF00005 ABC transporter 330 479 6.8E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS07350 9cb5f2a4730485884496490188aca11b 567 Pfam PF00005 ABC transporter 29 187 1.1E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS03330 6d9b8e069084c7491164cf3cbd90287b 208 SUPERFAMILY SSF46955 54 138 4.35E-14 T 29-03-2018 IPR009061 Putative DNA-binding domain SMALA_RS03330 6d9b8e069084c7491164cf3cbd90287b 208 Gene3D G3DSA:1.10.1660.10 49 126 1.1E-15 T 29-03-2018 SMALA_RS03330 6d9b8e069084c7491164cf3cbd90287b 208 Pfam PF13411 MerR HTH family regulatory protein 54 117 2.0E-13 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS03330 6d9b8e069084c7491164cf3cbd90287b 208 SMART SM00422 50 122 4.9E-18 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS42185 966e9d7ab5f18e773aea434d87b0d2dc 276 SUPERFAMILY SSF53474 3 268 4.36E-42 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS42185 966e9d7ab5f18e773aea434d87b0d2dc 276 PRINTS PR00111 Alpha/beta hydrolase fold signature 210 224 1.2E-6 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS42185 966e9d7ab5f18e773aea434d87b0d2dc 276 PRINTS PR00111 Alpha/beta hydrolase fold signature 104 117 1.2E-6 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS42185 966e9d7ab5f18e773aea434d87b0d2dc 276 PRINTS PR00111 Alpha/beta hydrolase fold signature 90 103 1.2E-6 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS42185 966e9d7ab5f18e773aea434d87b0d2dc 276 PRINTS PR00111 Alpha/beta hydrolase fold signature 45 60 1.2E-6 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS42185 966e9d7ab5f18e773aea434d87b0d2dc 276 Gene3D G3DSA:3.40.50.1820 174 270 2.9E-11 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS42185 966e9d7ab5f18e773aea434d87b0d2dc 276 Gene3D G3DSA:3.40.50.1820 2 173 3.1E-24 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS42185 966e9d7ab5f18e773aea434d87b0d2dc 276 Pfam PF12697 Alpha/beta hydrolase family 24 260 5.6E-17 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS05315 6e1fb2805d3077377c3da0eda698d585 471 Gene3D G3DSA:1.10.260.40 19 84 1.6E-9 T 29-03-2018 SMALA_RS05315 6e1fb2805d3077377c3da0eda698d585 471 SMART SM00530 26 82 1.4E-5 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS05315 6e1fb2805d3077377c3da0eda698d585 471 Pfam PF13560 Helix-turn-helix domain 22 85 4.6E-12 T 29-03-2018 SMALA_RS05315 6e1fb2805d3077377c3da0eda698d585 471 SUPERFAMILY SSF47413 25 94 5.63E-8 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS29440 bb4b1fa72820f0dc447770f6ef630595 91 Gene3D G3DSA:1.10.1200.10 16 91 3.3E-16 T 29-03-2018 SMALA_RS29440 bb4b1fa72820f0dc447770f6ef630595 91 Pfam PF00550 Phosphopantetheine attachment site 17 77 1.6E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS29440 bb4b1fa72820f0dc447770f6ef630595 91 SUPERFAMILY SSF47336 17 89 4.32E-17 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS21665 ee4ccbdf920862e8c440a53a5c1ebe4c 352 SUPERFAMILY SSF47781 277 344 9.27E-12 T 29-03-2018 IPR010994 RuvA domain 2-like SMALA_RS21665 ee4ccbdf920862e8c440a53a5c1ebe4c 352 Hamap MF_01438 DNA integrity scanning protein DisA [disA]. 1 349 43.615 T 29-03-2018 IPR023763 DNA integrity scanning protein, DisA SMALA_RS21665 ee4ccbdf920862e8c440a53a5c1ebe4c 352 Gene3D G3DSA:1.10.150.20 285 349 2.1E-9 T 29-03-2018 SMALA_RS21665 ee4ccbdf920862e8c440a53a5c1ebe4c 352 SUPERFAMILY SSF143597 10 132 6.15E-26 T 29-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal SMALA_RS21665 ee4ccbdf920862e8c440a53a5c1ebe4c 352 Pfam PF12826 Helix-hairpin-helix motif 302 339 1.4E-6 T 29-03-2018 SMALA_RS21665 ee4ccbdf920862e8c440a53a5c1ebe4c 352 Pfam PF10635 DisA bacterial checkpoint controller linker region 133 275 3.1E-52 T 29-03-2018 IPR018906 DNA integrity scanning, DisA, linker region SMALA_RS21665 ee4ccbdf920862e8c440a53a5c1ebe4c 352 Gene3D G3DSA:3.40.1700.10 1 133 4.2E-26 T 29-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal SMALA_RS21665 ee4ccbdf920862e8c440a53a5c1ebe4c 352 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 16 129 4.1E-23 T 29-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal SMALA_RS18685 ddf991867f91f78693a1196947a43c31 156 Gene3D G3DSA:1.10.10.410 95 154 5.1E-15 T 29-03-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal SMALA_RS18685 ddf991867f91f78693a1196947a43c31 156 Gene3D G3DSA:1.10.1510.10 3 94 2.6E-24 T 29-03-2018 SMALA_RS18685 ddf991867f91f78693a1196947a43c31 156 Pfam PF09424 Yqey-like protein 6 153 2.4E-43 T 29-03-2018 IPR019004 Uncharacterised domain YOR215C, mitochondrial SMALA_RS18685 ddf991867f91f78693a1196947a43c31 156 SUPERFAMILY SSF89095 4 153 8.37E-33 T 29-03-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 SMALA_RS30445 67eefe3d081c3348e15fd0fdb39f446f 296 SUPERFAMILY SSF55447 172 284 4.71E-20 T 29-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal SMALA_RS30445 67eefe3d081c3348e15fd0fdb39f446f 296 Gene3D G3DSA:3.30.465.10 52 166 3.8E-34 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SMALA_RS30445 67eefe3d081c3348e15fd0fdb39f446f 296 Gene3D G3DSA:3.30.390.50 167 291 7.0E-32 T 29-03-2018 SMALA_RS30445 67eefe3d081c3348e15fd0fdb39f446f 296 SUPERFAMILY SSF56176 2 164 8.05E-51 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SMALA_RS30445 67eefe3d081c3348e15fd0fdb39f446f 296 Gene3D G3DSA:3.30.43.10 5 51 6.4E-17 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 SMALA_RS30445 67eefe3d081c3348e15fd0fdb39f446f 296 SMART SM01092 171 281 7.9E-19 T 29-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal SMALA_RS30445 67eefe3d081c3348e15fd0fdb39f446f 296 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 2 164 6.3E-47 T 29-03-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 SMALA_RS30445 67eefe3d081c3348e15fd0fdb39f446f 296 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 173 278 7.0E-12 T 29-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal SMALA_RS05615 abaa5d0abaf29e378645ce06fac54847 309 Gene3D G3DSA:3.60.15.10 1 304 1.7E-41 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS05615 abaa5d0abaf29e378645ce06fac54847 309 SMART SM00849 65 279 1.3E-18 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS05615 abaa5d0abaf29e378645ce06fac54847 309 Pfam PF00753 Metallo-beta-lactamase superfamily 68 279 1.4E-25 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS05615 abaa5d0abaf29e378645ce06fac54847 309 SUPERFAMILY SSF56281 67 290 1.83E-31 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS22315 319a6d14e67c53879110dc3a0d87d434 287 Pfam PF01435 Peptidase family M48 70 282 1.2E-34 T 29-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 SMALA_RS22315 319a6d14e67c53879110dc3a0d87d434 287 Gene3D G3DSA:3.30.2010.10 58 150 1.8E-19 T 29-03-2018 SMALA_RS22315 319a6d14e67c53879110dc3a0d87d434 287 Hamap MF_00188 Protease HtpX [htpX]. 7 282 27.697 T 29-03-2018 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 SMALA_RS10270 4daad9905806433a275e825b23ddeb43 455 Pfam PF01882 Protein of unknown function DUF58 216 294 3.1E-21 T 29-03-2018 IPR002881 Domain of unknown function DUF58 SMALA_RS10270 4daad9905806433a275e825b23ddeb43 455 Gene3D G3DSA:3.40.50.410 221 443 2.2E-7 T 29-03-2018 IPR002035 von Willebrand factor, type A SMALA_RS00180 80f6771df61008e4109a8c80c8297991 306 Gene3D G3DSA:3.30.200.20 4 105 2.0E-9 T 29-03-2018 SMALA_RS00180 80f6771df61008e4109a8c80c8297991 306 Gene3D G3DSA:3.90.1200.10 106 291 6.1E-14 T 29-03-2018 SMALA_RS00180 80f6771df61008e4109a8c80c8297991 306 SUPERFAMILY SSF56112 5 254 1.87E-22 T 29-03-2018 IPR011009 Protein kinase-like domain SMALA_RS06400 e7b8fe1c8bec907be6753443fbe61b2b 365 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 108 198 2.5E-19 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 SMALA_RS06400 e7b8fe1c8bec907be6753443fbe61b2b 365 SUPERFAMILY SSF47203 218 361 1.53E-34 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMALA_RS06400 e7b8fe1c8bec907be6753443fbe61b2b 365 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 217 360 8.5E-30 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMALA_RS06400 e7b8fe1c8bec907be6753443fbe61b2b 365 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 104 1.7E-16 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS06400 e7b8fe1c8bec907be6753443fbe61b2b 365 Gene3D G3DSA:2.40.110.10 107 199 1.6E-29 T 29-03-2018 SMALA_RS06400 e7b8fe1c8bec907be6753443fbe61b2b 365 Gene3D G3DSA:1.10.540.10 4 106 6.0E-20 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS06400 e7b8fe1c8bec907be6753443fbe61b2b 365 SUPERFAMILY SSF56645 6 210 3.01E-54 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMALA_RS06400 e7b8fe1c8bec907be6753443fbe61b2b 365 Gene3D G3DSA:1.20.140.10 200 365 7.5E-34 T 29-03-2018 SMALA_RS31860 23e71cf5a17378206a63db9a7072b2ce 489 Pfam PF00171 Aldehyde dehydrogenase family 18 476 2.6E-164 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS31860 23e71cf5a17378206a63db9a7072b2ce 489 Gene3D G3DSA:3.40.605.10 2 266 8.0E-92 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS31860 23e71cf5a17378206a63db9a7072b2ce 489 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 276 287 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 SMALA_RS31860 23e71cf5a17378206a63db9a7072b2ce 489 Gene3D G3DSA:3.40.309.10 267 462 2.0E-74 T 29-03-2018 SMALA_RS31860 23e71cf5a17378206a63db9a7072b2ce 489 SUPERFAMILY SSF53720 3 481 1.31E-163 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMALA_RS31860 23e71cf5a17378206a63db9a7072b2ce 489 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 248 255 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 SMALA_RS28090 a208570fc330e4b04987c1c4ad29d1c5 222 SMART SM00943 27 210 7.7E-25 T 29-03-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal SMALA_RS28090 a208570fc330e4b04987c1c4ad29d1c5 222 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 29 203 2.0E-11 T 29-03-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal SMALA_RS20575 3eb3c4c7e96352e929b91d2e264fd0b6 311 SUPERFAMILY SSF47413 35 84 2.53E-7 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS20575 3eb3c4c7e96352e929b91d2e264fd0b6 311 Pfam PF13560 Helix-turn-helix domain 11 90 2.8E-15 T 29-03-2018 SMALA_RS20575 3eb3c4c7e96352e929b91d2e264fd0b6 311 SMART SM00530 14 87 7.5E-8 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS20575 3eb3c4c7e96352e929b91d2e264fd0b6 311 Gene3D G3DSA:1.10.260.40 1 105 3.9E-14 T 29-03-2018 SMALA_RS29990 d7c333783ee6d6dff21af3c1bcda5165 290 SUPERFAMILY SSF102462 199 287 2.96E-18 T 29-03-2018 IPR023476 Peptidyl-tRNA hydrolase II domain MetaCyc: PWY-6308 SMALA_RS29990 d7c333783ee6d6dff21af3c1bcda5165 290 Gene3D G3DSA:3.40.1490.10 196 290 4.9E-18 T 29-03-2018 IPR023476 Peptidyl-tRNA hydrolase II domain MetaCyc: PWY-6308 SMALA_RS29990 d7c333783ee6d6dff21af3c1bcda5165 290 Pfam PF01981 Peptidyl-tRNA hydrolase PTH2 206 287 1.8E-7 T 29-03-2018 IPR002833 Peptidyl-tRNA hydrolase, PTH2 GO:0004045 MetaCyc: PWY-6308 SMALA_RS08900 d47f79d0a0166b1b70dab7a5ebfdee9c 410 TIGRFAM TIGR00338 serB: phosphoserine phosphatase SerB 184 395 4.8E-76 T 29-03-2018 SMALA_RS08900 d47f79d0a0166b1b70dab7a5ebfdee9c 410 Gene3D G3DSA:3.40.50.1000 250 395 2.1E-27 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS08900 d47f79d0a0166b1b70dab7a5ebfdee9c 410 Gene3D G3DSA:3.30.70.260 107 188 1.2E-11 T 29-03-2018 SMALA_RS08900 d47f79d0a0166b1b70dab7a5ebfdee9c 410 Gene3D G3DSA:1.10.150.210 203 249 1.8E-22 T 29-03-2018 IPR023190 Phosphoserine phosphatase, domain 2 GO:0004647|GO:0006564 KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3|Reactome: R-HSA-977347 SMALA_RS08900 d47f79d0a0166b1b70dab7a5ebfdee9c 410 Gene3D G3DSA:3.30.70.260 9 106 1.2E-14 T 29-03-2018 SMALA_RS08900 d47f79d0a0166b1b70dab7a5ebfdee9c 410 Pfam PF13740 ACT domain 19 93 6.5E-18 T 29-03-2018 SMALA_RS08900 d47f79d0a0166b1b70dab7a5ebfdee9c 410 SUPERFAMILY SSF56784 191 397 3.25E-48 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS08900 d47f79d0a0166b1b70dab7a5ebfdee9c 410 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 192 362 2.1E-28 T 29-03-2018 SMALA_RS08900 d47f79d0a0166b1b70dab7a5ebfdee9c 410 Pfam PF12710 haloacid dehalogenase-like hydrolase 193 360 5.3E-24 T 29-03-2018 SMALA_RS08900 d47f79d0a0166b1b70dab7a5ebfdee9c 410 SUPERFAMILY SSF55021 20 92 2.2E-10 T 29-03-2018 SMALA_RS06965 28566c5783877d741fb4b7663c5a9110 201 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 19 198 6.6E-29 T 29-03-2018 IPR004302 Cellulose/chitin-binding protein, N-terminal SMALA_RS06965 28566c5783877d741fb4b7663c5a9110 201 SUPERFAMILY SSF81296 19 201 3.92E-27 T 29-03-2018 IPR014756 Immunoglobulin E-set SMALA_RS06965 28566c5783877d741fb4b7663c5a9110 201 Gene3D G3DSA:2.70.50.50 19 201 1.1E-46 T 29-03-2018 SMALA_RS25510 815824cc9055cdd6d61f7dbf5e85e758 342 Gene3D G3DSA:3.90.1200.10 99 307 1.3E-12 T 29-03-2018 SMALA_RS25510 815824cc9055cdd6d61f7dbf5e85e758 342 SUPERFAMILY SSF56112 17 243 8.27E-32 T 29-03-2018 IPR011009 Protein kinase-like domain SMALA_RS25510 815824cc9055cdd6d61f7dbf5e85e758 342 Pfam PF01636 Phosphotransferase enzyme family 23 234 1.8E-13 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase SMALA_RS25510 815824cc9055cdd6d61f7dbf5e85e758 342 Gene3D G3DSA:3.30.200.20 6 92 3.6E-6 T 29-03-2018 SMALA_RS12185 fa1206d5759090de08b62b2fce4c0a73 146 Gene3D G3DSA:3.40.30.10 2 145 3.1E-36 T 29-03-2018 SMALA_RS12185 fa1206d5759090de08b62b2fce4c0a73 146 Pfam PF00085 Thioredoxin 5 102 7.0E-28 T 29-03-2018 IPR013766 Thioredoxin domain GO:0045454 SMALA_RS12185 fa1206d5759090de08b62b2fce4c0a73 146 TIGRFAM TIGR01068 thioredoxin: thioredoxin 9 104 7.4E-31 T 29-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 SMALA_RS12185 fa1206d5759090de08b62b2fce4c0a73 146 SUPERFAMILY SSF52833 4 104 7.06E-33 T 29-03-2018 IPR012336 Thioredoxin-like fold SMALA_RS12185 fa1206d5759090de08b62b2fce4c0a73 146 ProSitePatterns PS00194 Thioredoxin family active site. 24 42 - T 29-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 SMALA_RS12185 fa1206d5759090de08b62b2fce4c0a73 146 PRINTS PR00421 Thioredoxin family signature 70 81 1.4E-7 T 29-03-2018 SMALA_RS12185 fa1206d5759090de08b62b2fce4c0a73 146 PRINTS PR00421 Thioredoxin family signature 31 40 1.4E-7 T 29-03-2018 SMALA_RS12185 fa1206d5759090de08b62b2fce4c0a73 146 PRINTS PR00421 Thioredoxin family signature 23 31 1.4E-7 T 29-03-2018 SMALA_RS07050 53fef50325280425455935822b506dd2 65 Gene3D G3DSA:1.10.443.10 1 40 1.8E-5 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 SMALA_RS34795 ed409b4ed54999ebba0d9cda2541dff6 100 Gene3D G3DSA:3.30.280.10 2 99 1.1E-46 T 29-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMALA_RS34795 ed409b4ed54999ebba0d9cda2541dff6 100 Hamap MF_00739 Urease subunit gamma [ureA]. 1 100 33.497 T 29-03-2018 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMALA_RS34795 ed409b4ed54999ebba0d9cda2541dff6 100 SUPERFAMILY SSF54111 1 99 1.57E-44 T 29-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMALA_RS34795 ed409b4ed54999ebba0d9cda2541dff6 100 ProDom PD002319 SUBUNIT GAMMA HYDROLASE UREASE UREA AMIDOHYDROLASE UREASE ALPHA GAMMA/BETA METAL-BINDING 9 99 4.0E-39 T 29-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMALA_RS34795 ed409b4ed54999ebba0d9cda2541dff6 100 PIRSF PIRSF001223 1 100 4.0E-50 T 29-03-2018 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMALA_RS34795 ed409b4ed54999ebba0d9cda2541dff6 100 TIGRFAM TIGR00193 urease_gam: urease, gamma subunit 1 99 2.6E-49 T 29-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMALA_RS34795 ed409b4ed54999ebba0d9cda2541dff6 100 Pfam PF00547 Urease, gamma subunit 1 99 7.3E-46 T 29-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMALA_RS37420 b69181a3f1881c4fed0b7964a1f12685 292 Pfam PF00582 Universal stress protein family 5 139 5.8E-19 T 29-03-2018 IPR006016 UspA GO:0006950 SMALA_RS37420 b69181a3f1881c4fed0b7964a1f12685 292 Pfam PF00582 Universal stress protein family 150 289 2.6E-17 T 29-03-2018 IPR006016 UspA GO:0006950 SMALA_RS37420 b69181a3f1881c4fed0b7964a1f12685 292 Gene3D G3DSA:3.40.50.620 145 292 3.7E-23 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS37420 b69181a3f1881c4fed0b7964a1f12685 292 SUPERFAMILY SSF52402 5 142 1.93E-22 T 29-03-2018 SMALA_RS37420 b69181a3f1881c4fed0b7964a1f12685 292 Gene3D G3DSA:3.40.50.620 3 144 6.0E-25 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS37420 b69181a3f1881c4fed0b7964a1f12685 292 PRINTS PR01438 Universal stress protein signature 249 261 2.0E-10 T 29-03-2018 IPR006015 Universal stress protein A SMALA_RS37420 b69181a3f1881c4fed0b7964a1f12685 292 PRINTS PR01438 Universal stress protein signature 2 20 2.0E-10 T 29-03-2018 IPR006015 Universal stress protein A SMALA_RS37420 b69181a3f1881c4fed0b7964a1f12685 292 PRINTS PR01438 Universal stress protein signature 267 289 2.0E-10 T 29-03-2018 IPR006015 Universal stress protein A SMALA_RS37420 b69181a3f1881c4fed0b7964a1f12685 292 SUPERFAMILY SSF52402 150 289 5.11E-20 T 29-03-2018 SMALA_RS23935 27a14f973da3bad1b4fd3f98d2756fc8 291 Gene3D G3DSA:3.30.950.10 115 227 6.4E-43 T 29-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMALA_RS23935 27a14f973da3bad1b4fd3f98d2756fc8 291 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 6 272 5.4E-59 T 29-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SMALA_RS23935 27a14f973da3bad1b4fd3f98d2756fc8 291 SUPERFAMILY SSF53790 3 222 4.71E-73 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMALA_RS23935 27a14f973da3bad1b4fd3f98d2756fc8 291 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 4 207 3.6E-31 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMALA_RS23935 27a14f973da3bad1b4fd3f98d2756fc8 291 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 4 224 32.496 T 29-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SMALA_RS23935 27a14f973da3bad1b4fd3f98d2756fc8 291 Gene3D G3DSA:3.40.1010.10 2 114 1.4E-32 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMALA_RS23935 27a14f973da3bad1b4fd3f98d2756fc8 291 PIRSF PIRSF005917 1 280 2.5E-89 T 29-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SMALA_RS22750 123e20a4700b6fc47a1153c462397c9f 452 Gene3D G3DSA:3.40.120.10 2 148 7.0E-44 T 29-03-2018 SMALA_RS22750 123e20a4700b6fc47a1153c462397c9f 452 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 5 448 4.7E-170 T 29-03-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMALA_RS22750 123e20a4700b6fc47a1153c462397c9f 452 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 164 259 5.9E-18 T 29-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMALA_RS22750 123e20a4700b6fc47a1153c462397c9f 452 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 263 374 1.6E-32 T 29-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMALA_RS22750 123e20a4700b6fc47a1153c462397c9f 452 Gene3D G3DSA:3.40.120.10 162 274 2.8E-29 T 29-03-2018 SMALA_RS22750 123e20a4700b6fc47a1153c462397c9f 452 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 98 107 - T 29-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMALA_RS22750 123e20a4700b6fc47a1153c462397c9f 452 Gene3D G3DSA:3.40.120.10 275 379 1.2E-31 T 29-03-2018 SMALA_RS22750 123e20a4700b6fc47a1153c462397c9f 452 SUPERFAMILY SSF53738 4 185 2.98E-44 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMALA_RS22750 123e20a4700b6fc47a1153c462397c9f 452 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 380 447 1.2E-14 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMALA_RS22750 123e20a4700b6fc47a1153c462397c9f 452 SUPERFAMILY SSF53738 263 370 1.65E-29 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMALA_RS22750 123e20a4700b6fc47a1153c462397c9f 452 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 1 450 43.854 T 29-03-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMALA_RS22750 123e20a4700b6fc47a1153c462397c9f 452 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 239 254 8.3E-14 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMALA_RS22750 123e20a4700b6fc47a1153c462397c9f 452 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 179 198 8.3E-14 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMALA_RS22750 123e20a4700b6fc47a1153c462397c9f 452 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 97 111 8.3E-14 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMALA_RS22750 123e20a4700b6fc47a1153c462397c9f 452 SUPERFAMILY SSF55957 364 452 3.53E-23 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMALA_RS22750 123e20a4700b6fc47a1153c462397c9f 452 Gene3D G3DSA:3.30.310.50 380 452 4.4E-19 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMALA_RS22750 123e20a4700b6fc47a1153c462397c9f 452 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 138 7.8E-39 T 29-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMALA_RS22750 123e20a4700b6fc47a1153c462397c9f 452 SUPERFAMILY SSF53738 163 261 4.32E-25 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMALA_RS37445 8ffb965bbf6c63bab687b919a774b9ad 99 Pfam PF01455 HupF/HypC family 1 69 1.4E-25 T 29-03-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC SMALA_RS37445 8ffb965bbf6c63bab687b919a774b9ad 99 ProSitePatterns PS01097 Hydrogenases expression/synthesis hupF/hypC family signature. 1 9 - T 29-03-2018 IPR019812 Hydrogenase assembly chaperone, conserved site SMALA_RS37445 8ffb965bbf6c63bab687b919a774b9ad 99 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 60 72 8.3E-13 T 29-03-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC SMALA_RS37445 8ffb965bbf6c63bab687b919a774b9ad 99 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 21 37 8.3E-13 T 29-03-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC SMALA_RS37445 8ffb965bbf6c63bab687b919a774b9ad 99 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 2 9 8.3E-13 T 29-03-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC SMALA_RS37445 8ffb965bbf6c63bab687b919a774b9ad 99 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 42 58 8.3E-13 T 29-03-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC SMALA_RS37445 8ffb965bbf6c63bab687b919a774b9ad 99 TIGRFAM TIGR00074 hypC_hupF: hydrogenase assembly chaperone HypC/HupF 1 78 5.1E-21 T 29-03-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC SMALA_RS37445 8ffb965bbf6c63bab687b919a774b9ad 99 SUPERFAMILY SSF159127 1 83 2.35E-23 T 29-03-2018 SMALA_RS41570 610234b92bae5fd3e96297af40a45cae 170 Gene3D G3DSA:2.30.110.10 11 168 1.7E-40 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS41570 610234b92bae5fd3e96297af40a45cae 170 SUPERFAMILY SSF50475 14 166 1.52E-44 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS41570 610234b92bae5fd3e96297af40a45cae 170 SMART SM00903 23 167 8.5E-53 T 29-03-2018 IPR002563 Flavin reductase like domain GO:0010181 SMALA_RS41570 610234b92bae5fd3e96297af40a45cae 170 Pfam PF01613 Flavin reductase like domain 23 166 3.7E-36 T 29-03-2018 IPR002563 Flavin reductase like domain GO:0010181 SMALA_RS34540 dfcc9b42e8c91ce29c6a2d3fa90e1d66 343 Pfam PF12833 Helix-turn-helix domain 238 324 3.3E-21 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS34540 dfcc9b42e8c91ce29c6a2d3fa90e1d66 343 Gene3D G3DSA:1.10.10.60 209 258 3.2E-7 T 29-03-2018 SMALA_RS34540 dfcc9b42e8c91ce29c6a2d3fa90e1d66 343 Pfam PF14525 AraC-binding-like domain 21 196 2.2E-20 T 29-03-2018 IPR035418 Transcription regulator HTH, AraC- type, ligand binding domain-like SMALA_RS34540 dfcc9b42e8c91ce29c6a2d3fa90e1d66 343 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 292 307 2.9E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SMALA_RS34540 dfcc9b42e8c91ce29c6a2d3fa90e1d66 343 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 307 323 2.9E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SMALA_RS34540 dfcc9b42e8c91ce29c6a2d3fa90e1d66 343 SMART SM00342 232 323 5.0E-24 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS34540 dfcc9b42e8c91ce29c6a2d3fa90e1d66 343 Gene3D G3DSA:1.10.10.60 272 333 9.5E-14 T 29-03-2018 SMALA_RS34540 dfcc9b42e8c91ce29c6a2d3fa90e1d66 343 SUPERFAMILY SSF46689 273 325 8.51E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS30205 8fbdde796a2735ec526710c996f2902f 198 Pfam PF05685 Putative restriction endonuclease 21 177 5.8E-19 T 29-03-2018 IPR008538 Domain of unknown function DUF820 SMALA_RS30205 8fbdde796a2735ec526710c996f2902f 198 Gene3D G3DSA:3.90.1570.10 9 196 1.0E-28 T 29-03-2018 SMALA_RS30205 8fbdde796a2735ec526710c996f2902f 198 SUPERFAMILY SSF52980 16 173 6.97E-21 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 SMALA_RS32985 c7f9c1df4bf3f76eeab099fa6e7cd166 290 SUPERFAMILY SSF52540 4 228 2.77E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS32985 c7f9c1df4bf3f76eeab099fa6e7cd166 290 SMART SM00382 30 216 9.9E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS32985 c7f9c1df4bf3f76eeab099fa6e7cd166 290 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS32985 c7f9c1df4bf3f76eeab099fa6e7cd166 290 Pfam PF00005 ABC transporter 21 159 1.0E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS32985 c7f9c1df4bf3f76eeab099fa6e7cd166 290 Gene3D G3DSA:3.40.50.300 2 259 7.1E-65 T 29-03-2018 SMALA_RS08315 069d655f74c6d8dd6229cd6faaa65712 268 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 40 256 1.2E-21 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain SMALA_RS08315 069d655f74c6d8dd6229cd6faaa65712 268 SUPERFAMILY SSF52266 38 256 2.83E-61 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain SMALA_RS08315 069d655f74c6d8dd6229cd6faaa65712 268 Gene3D G3DSA:3.40.50.1110 32 257 4.7E-35 T 29-03-2018 SMALA_RS23560 cc86b98fd8072ca31026508d63c6c417 210 Gene3D G3DSA:1.20.120.520 2 155 2.2E-21 T 29-03-2018 SMALA_RS23560 cc86b98fd8072ca31026508d63c6c417 210 Pfam PF01814 Hemerythrin HHE cation binding domain 17 135 5.1E-10 T 29-03-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 SMALA_RS08750 1e9724f0a84bcc3ae92ba50b7235097e 306 Gene3D G3DSA:2.60.200.30 151 273 1.2E-36 T 29-03-2018 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 SMALA_RS08750 1e9724f0a84bcc3ae92ba50b7235097e 306 Pfam PF01513 ATP-NAD kinase 62 280 1.2E-55 T 29-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 SMALA_RS08750 1e9724f0a84bcc3ae92ba50b7235097e 306 Gene3D G3DSA:3.40.50.10330 10 150 1.6E-33 T 29-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 SMALA_RS08750 1e9724f0a84bcc3ae92ba50b7235097e 306 SUPERFAMILY SSF111331 14 302 1.57E-77 T 29-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain SMALA_RS08750 1e9724f0a84bcc3ae92ba50b7235097e 306 Hamap MF_00361 NAD kinase [nadK]. 13 296 29.281 T 29-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 SMALA_RS14250 de234c447107b9309efe9151b1f01e4d 202 Pfam PF00929 Exonuclease 6 168 3.0E-24 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III SMALA_RS14250 de234c447107b9309efe9151b1f01e4d 202 Hamap MF_00045 Oligoribonuclease [orn]. 1 179 37.457 T 29-03-2018 IPR022894 Oligoribonuclease GO:0000175 SMALA_RS14250 de234c447107b9309efe9151b1f01e4d 202 SUPERFAMILY SSF53098 3 177 1.17E-40 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SMALA_RS14250 de234c447107b9309efe9151b1f01e4d 202 Gene3D G3DSA:3.30.420.10 1 178 8.0E-29 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SMALA_RS14250 de234c447107b9309efe9151b1f01e4d 202 SMART SM00479 4 178 3.6E-24 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III SMALA_RS11720 4a728d1b591c97901d44a4e50bdb7b88 220 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 19 186 2.1E-19 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SMALA_RS11720 4a728d1b591c97901d44a4e50bdb7b88 220 Gene3D G3DSA:3.40.50.1240 2 189 2.7E-24 T 29-03-2018 IPR029033 Histidine phosphatase superfamily SMALA_RS11720 4a728d1b591c97901d44a4e50bdb7b88 220 SMART SM00855 18 158 8.9E-5 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SMALA_RS11720 4a728d1b591c97901d44a4e50bdb7b88 220 SUPERFAMILY SSF53254 16 206 3.27E-26 T 29-03-2018 IPR029033 Histidine phosphatase superfamily SMALA_RS36905 3f3b48c596703ec30f8fd637cf6388e1 383 Pfam PF13478 XdhC Rossmann domain 206 352 6.0E-42 T 29-03-2018 IPR027051 XdhC Rossmann domain SMALA_RS36905 3f3b48c596703ec30f8fd637cf6388e1 383 Pfam PF02625 XdhC and CoxI family 116 183 2.6E-19 T 29-03-2018 IPR003777 XdhC- CoxI SMALA_RS36905 3f3b48c596703ec30f8fd637cf6388e1 383 Pfam PF02625 XdhC and CoxI family 11 78 4.0E-23 T 29-03-2018 IPR003777 XdhC- CoxI SMALA_RS16495 d89d0eae03fd1f94245a5816973270a2 425 Pfam PF00591 Glycosyl transferase family, a/b domain 78 284 1.1E-33 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 SMALA_RS16495 d89d0eae03fd1f94245a5816973270a2 425 PIRSF PIRSF000478 1 424 2.7E-152 T 29-03-2018 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 SMALA_RS16495 d89d0eae03fd1f94245a5816973270a2 425 SUPERFAMILY SSF47648 1 69 1.2E-20 T 29-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 SMALA_RS16495 d89d0eae03fd1f94245a5816973270a2 425 Pfam PF02885 Glycosyl transferase family, helical bundle domain 6 66 8.1E-19 T 29-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 SMALA_RS16495 d89d0eae03fd1f94245a5816973270a2 425 Gene3D G3DSA:1.20.970.10 1 66 1.9E-23 T 29-03-2018 SMALA_RS16495 d89d0eae03fd1f94245a5816973270a2 425 SMART SM00941 334 408 9.3E-34 T 29-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 SMALA_RS16495 d89d0eae03fd1f94245a5816973270a2 425 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 110 125 - T 29-03-2018 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 SMALA_RS16495 d89d0eae03fd1f94245a5816973270a2 425 TIGRFAM TIGR02644 Y_phosphoryl: pyrimidine-nucleoside phosphorylase 4 406 2.3E-168 T 29-03-2018 IPR018090 Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic GO:0006213|GO:0016154 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181|Reactome: R-HSA-73614|Reactome: R-HSA-73621 SMALA_RS16495 d89d0eae03fd1f94245a5816973270a2 425 Gene3D G3DSA:3.90.1170.30 329 413 1.6E-28 T 29-03-2018 SMALA_RS16495 d89d0eae03fd1f94245a5816973270a2 425 SUPERFAMILY SSF54680 321 414 4.71E-25 T 29-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 SMALA_RS16495 d89d0eae03fd1f94245a5816973270a2 425 SUPERFAMILY SSF52418 69 316 1.03E-81 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 SMALA_RS16495 d89d0eae03fd1f94245a5816973270a2 425 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 335 407 1.2E-22 T 29-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 SMALA_RS16495 d89d0eae03fd1f94245a5816973270a2 425 Gene3D G3DSA:3.40.1030.10 68 328 1.6E-82 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 SMALA_RS20550 1cf55620c8c857e8077cd612ca09b4e7 63 Gene3D G3DSA:3.30.70.20 1 63 9.3E-7 T 29-03-2018 SMALA_RS20550 1cf55620c8c857e8077cd612ca09b4e7 63 SUPERFAMILY SSF54862 2 61 4.19E-11 T 29-03-2018 SMALA_RS20550 1cf55620c8c857e8077cd612ca09b4e7 63 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 5.4E-5 T 29-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 SMALA_RS20550 1cf55620c8c857e8077cd612ca09b4e7 63 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 5.4E-5 T 29-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 SMALA_RS20550 1cf55620c8c857e8077cd612ca09b4e7 63 PRINTS PR00352 3Fe-4S ferredoxin signature 47 59 5.4E-5 T 29-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 SMALA_RS20550 1cf55620c8c857e8077cd612ca09b4e7 63 Pfam PF13459 4Fe-4S single cluster domain 3 61 1.5E-11 T 29-03-2018 SMALA_RS04065 b822007d3d8e4e96708934082999c6f3 168 Pfam PF01613 Flavin reductase like domain 22 166 4.0E-35 T 29-03-2018 IPR002563 Flavin reductase like domain GO:0010181 SMALA_RS04065 b822007d3d8e4e96708934082999c6f3 168 Gene3D G3DSA:2.30.110.10 1 167 8.9E-41 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS04065 b822007d3d8e4e96708934082999c6f3 168 SMART SM00903 22 165 9.6E-50 T 29-03-2018 IPR002563 Flavin reductase like domain GO:0010181 SMALA_RS04065 b822007d3d8e4e96708934082999c6f3 168 SUPERFAMILY SSF50475 16 165 1.32E-41 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS17350 4580ad4369890f007c83993e840d89be 485 SUPERFAMILY SSF103473 90 246 5.75E-17 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS17350 4580ad4369890f007c83993e840d89be 485 SUPERFAMILY SSF103473 281 467 5.75E-17 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS17350 4580ad4369890f007c83993e840d89be 485 ProSitePatterns PS00099 Thiolases active site. 337 350 - T 29-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 SMALA_RS17350 4580ad4369890f007c83993e840d89be 485 Gene3D G3DSA:1.20.1250.20 64 255 1.2E-10 T 29-03-2018 SMALA_RS17350 4580ad4369890f007c83993e840d89be 485 Pfam PF07690 Major Facilitator Superfamily 88 438 2.8E-12 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS17350 4580ad4369890f007c83993e840d89be 485 Gene3D G3DSA:1.20.1250.20 291 477 3.2E-5 T 29-03-2018 SMALA_RS24925 0ef197f8a034f0533d8857065acb7fc7 559 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 377 540 6.5E-57 T 29-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 SMALA_RS24925 0ef197f8a034f0533d8857065acb7fc7 559 ProSitePatterns PS00163 Fumarate lyases signature. 460 469 - T 29-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 SMALA_RS24925 0ef197f8a034f0533d8857065acb7fc7 559 Pfam PF05681 Fumarate hydratase (Fumerase) 48 324 4.6E-90 T 29-03-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 SMALA_RS24925 0ef197f8a034f0533d8857065acb7fc7 559 SUPERFAMILY SSF117457 366 540 2.75E-61 T 29-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 SMALA_RS24925 0ef197f8a034f0533d8857065acb7fc7 559 PIRSF PIRSF001394 28 555 8.0E-226 T 29-03-2018 IPR011167 Iron-dependent fumarate hydratase GO:0004333|GO:0006091 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384 SMALA_RS24925 0ef197f8a034f0533d8857065acb7fc7 559 Pfam PF05683 Fumarase C-terminus 330 541 1.6E-91 T 29-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 SMALA_RS24925 0ef197f8a034f0533d8857065acb7fc7 559 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 52 325 1.9E-33 T 29-03-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 SMALA_RS24925 0ef197f8a034f0533d8857065acb7fc7 559 Gene3D G3DSA:3.20.130.10 363 540 8.2E-68 T 29-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 SMALA_RS10445 34ccf1c90a472baf16ce4c8574f534fe 155 Pfam PF17230 Family of unknown function (DUF5304) 22 155 2.5E-54 T 29-03-2018 IPR035183 Protein of unknown function DUF5304 SMALA_RS04520 59d8427eec55ef769c26db945062bae6 269 Gene3D G3DSA:1.10.3720.10 66 261 1.6E-28 T 29-03-2018 SMALA_RS04520 59d8427eec55ef769c26db945062bae6 269 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 257 4.0E-25 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS04520 59d8427eec55ef769c26db945062bae6 269 SUPERFAMILY SSF161098 66 252 8.24E-34 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS12910 6c5ea19ecaca06704d73620336ea81a8 165 SUPERFAMILY SSF55486 3 149 9.28E-37 T 29-03-2018 SMALA_RS12910 6c5ea19ecaca06704d73620336ea81a8 165 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 36 148 3.6E-31 T 29-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 SMALA_RS12910 6c5ea19ecaca06704d73620336ea81a8 165 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 2 157 21.674 T 29-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 SMALA_RS12910 6c5ea19ecaca06704d73620336ea81a8 165 Pfam PF02130 Uncharacterized protein family UPF0054 18 147 2.1E-36 T 29-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 SMALA_RS12910 6c5ea19ecaca06704d73620336ea81a8 165 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 119 129 - T 29-03-2018 IPR020549 Endoribonuclease YbeY, conserved site SMALA_RS12910 6c5ea19ecaca06704d73620336ea81a8 165 Gene3D G3DSA:3.40.390.30 1 157 2.0E-41 T 29-03-2018 IPR023091 Metalloprotease catalytic domain, predicted GO:0004222 SMALA_RS04300 c2e74b30ccbf58369d194362225eeb5e 530 Gene3D G3DSA:3.90.76.10 68 207 3.9E-27 T 29-03-2018 SMALA_RS04300 c2e74b30ccbf58369d194362225eeb5e 530 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 103 442 8.7E-75 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain SMALA_RS04300 c2e74b30ccbf58369d194362225eeb5e 530 Gene3D G3DSA:3.10.105.10 302 494 1.4E-36 T 29-03-2018 SMALA_RS04300 c2e74b30ccbf58369d194362225eeb5e 530 Gene3D G3DSA:3.40.190.10 208 301 1.5E-27 T 29-03-2018 SMALA_RS04300 c2e74b30ccbf58369d194362225eeb5e 530 PIRSF PIRSF002741 20 515 1.0E-76 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 SMALA_RS04300 c2e74b30ccbf58369d194362225eeb5e 530 SUPERFAMILY SSF53850 53 529 3.62E-106 T 29-03-2018 SMALA_RS35395 ed338f2863372e45eccc5040546dafbc 436 Pfam PF07158 Dicarboxylate carrier protein MatC N-terminus 1 149 9.1E-64 T 29-03-2018 IPR009827 Dicarboxylate carrier MatC N-terminal SMALA_RS27850 41df1e66b66311c1a003dc12249c8cec 136 Pfam PF05331 Protein of unknown function (DUF742) 24 136 3.4E-39 T 29-03-2018 IPR007995 Protein of unknown function DUF742 SMALA_RS01510 59254298d6ab413e1d1d5b508915b482 378 Pfam PF12671 Putative amidase domain 224 375 3.4E-34 T 29-03-2018 IPR024301 Putative amidase domain SMALA_RS01510 59254298d6ab413e1d1d5b508915b482 378 Gene3D G3DSA:3.90.1720.10 216 378 3.4E-10 T 29-03-2018 SMALA_RS19775 51a8f7fa7f815087df44efbe889e7df1 589 Pfam PF00069 Protein kinase domain 9 247 2.6E-37 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMALA_RS19775 51a8f7fa7f815087df44efbe889e7df1 589 Gene3D G3DSA:3.30.200.20 2 98 1.2E-14 T 29-03-2018 SMALA_RS19775 51a8f7fa7f815087df44efbe889e7df1 589 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 123 135 - T 29-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMALA_RS19775 51a8f7fa7f815087df44efbe889e7df1 589 PRINTS PR01217 Proline rich extensin signature 347 368 7.7E-9 T 29-03-2018 SMALA_RS19775 51a8f7fa7f815087df44efbe889e7df1 589 PRINTS PR01217 Proline rich extensin signature 412 429 7.7E-9 T 29-03-2018 SMALA_RS19775 51a8f7fa7f815087df44efbe889e7df1 589 PRINTS PR01217 Proline rich extensin signature 430 455 7.7E-9 T 29-03-2018 SMALA_RS19775 51a8f7fa7f815087df44efbe889e7df1 589 PRINTS PR01217 Proline rich extensin signature 382 398 7.7E-9 T 29-03-2018 SMALA_RS19775 51a8f7fa7f815087df44efbe889e7df1 589 PRINTS PR01217 Proline rich extensin signature 282 294 7.7E-9 T 29-03-2018 SMALA_RS19775 51a8f7fa7f815087df44efbe889e7df1 589 Gene3D G3DSA:1.10.510.10 99 382 3.1E-38 T 29-03-2018 SMALA_RS19775 51a8f7fa7f815087df44efbe889e7df1 589 SMART SM00220 9 257 1.1E-39 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMALA_RS19775 51a8f7fa7f815087df44efbe889e7df1 589 SUPERFAMILY SSF56112 437 526 1.29E-63 T 29-03-2018 IPR011009 Protein kinase-like domain SMALA_RS19775 51a8f7fa7f815087df44efbe889e7df1 589 SUPERFAMILY SSF56112 5 262 1.29E-63 T 29-03-2018 IPR011009 Protein kinase-like domain SMALA_RS21225 651d652b7917fe90e0226ce3d3fc3087 451 Gene3D G3DSA:3.40.50.720 168 391 2.4E-29 T 29-03-2018 SMALA_RS21225 651d652b7917fe90e0226ce3d3fc3087 451 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 337 1.8E-40 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS21225 651d652b7917fe90e0226ce3d3fc3087 451 SUPERFAMILY SSF51905 172 355 2.18E-16 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS21225 651d652b7917fe90e0226ce3d3fc3087 451 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 113 131 6.3E-10 T 29-03-2018 SMALA_RS21225 651d652b7917fe90e0226ce3d3fc3087 451 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 6.3E-10 T 29-03-2018 SMALA_RS21225 651d652b7917fe90e0226ce3d3fc3087 451 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 173 191 6.3E-10 T 29-03-2018 SMALA_RS21225 651d652b7917fe90e0226ce3d3fc3087 451 Gene3D G3DSA:3.50.50.60 5 167 1.2E-16 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS21225 651d652b7917fe90e0226ce3d3fc3087 451 SUPERFAMILY SSF51905 4 231 8.1E-25 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS16570 994e421ad89e0b0abfb5f1b786bddeca 295 Gene3D G3DSA:1.10.510.10 64 289 1.4E-25 T 29-03-2018 SMALA_RS16570 994e421ad89e0b0abfb5f1b786bddeca 295 Pfam PF01636 Phosphotransferase enzyme family 36 258 8.6E-34 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase SMALA_RS16570 994e421ad89e0b0abfb5f1b786bddeca 295 SUPERFAMILY SSF56112 20 267 4.48E-45 T 29-03-2018 IPR011009 Protein kinase-like domain SMALA_RS22335 7a3afd2b91b68136d94f7b0305a6afca 324 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 71 1.7E-4 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS22335 7a3afd2b91b68136d94f7b0305a6afca 324 Pfam PF00107 Zinc-binding dehydrogenase 152 269 1.3E-14 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMALA_RS22335 7a3afd2b91b68136d94f7b0305a6afca 324 Gene3D G3DSA:3.40.50.720 135 292 1.9E-24 T 29-03-2018 SMALA_RS22335 7a3afd2b91b68136d94f7b0305a6afca 324 SUPERFAMILY SSF50129 1 140 4.87E-30 T 29-03-2018 IPR011032 GroES-like SMALA_RS22335 7a3afd2b91b68136d94f7b0305a6afca 324 SMART SM00829 10 322 3.0E-11 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS22335 7a3afd2b91b68136d94f7b0305a6afca 324 SUPERFAMILY SSF51735 113 293 2.18E-27 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS22335 7a3afd2b91b68136d94f7b0305a6afca 324 Gene3D G3DSA:3.90.180.10 1 134 5.3E-29 T 29-03-2018 SMALA_RS00435 ab51103146fb70dc4f541a58a3e03199 311 Gene3D G3DSA:3.40.50.150 31 309 1.5E-25 T 29-03-2018 SMALA_RS00435 ab51103146fb70dc4f541a58a3e03199 311 SUPERFAMILY SSF53335 134 287 3.92E-28 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS00435 ab51103146fb70dc4f541a58a3e03199 311 Pfam PF13489 Methyltransferase domain 146 280 1.3E-14 T 29-03-2018 SMALA_RS42085 7c78c6b0674a82d759944c35fdb69e15 614 Pfam PF00733 Asparagine synthase 240 602 1.0E-87 T 29-03-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 SMALA_RS42085 7c78c6b0674a82d759944c35fdb69e15 614 SUPERFAMILY SSF52402 229 395 4.47E-63 T 29-03-2018 SMALA_RS42085 7c78c6b0674a82d759944c35fdb69e15 614 SUPERFAMILY SSF52402 458 584 4.47E-63 T 29-03-2018 SMALA_RS42085 7c78c6b0674a82d759944c35fdb69e15 614 PIRSF PIRSF001589 1 613 7.1E-140 T 29-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 SMALA_RS42085 7c78c6b0674a82d759944c35fdb69e15 614 Pfam PF13537 Glutamine amidotransferase domain 48 169 1.5E-46 T 29-03-2018 IPR017932 Glutamine amidotransferase type 2 domain SMALA_RS42085 7c78c6b0674a82d759944c35fdb69e15 614 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 538 2.4E-150 T 29-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 SMALA_RS42085 7c78c6b0674a82d759944c35fdb69e15 614 SUPERFAMILY SSF56235 1 224 3.26E-64 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SMALA_RS42085 7c78c6b0674a82d759944c35fdb69e15 614 Gene3D G3DSA:3.60.20.10 1 221 2.9E-58 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SMALA_RS42085 7c78c6b0674a82d759944c35fdb69e15 614 Gene3D G3DSA:3.40.50.620 222 606 2.5E-60 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS17170 90225f86e20e8127cd43e6e0b64a9375 289 Pfam PF00561 alpha/beta hydrolase fold 38 142 1.3E-19 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS17170 90225f86e20e8127cd43e6e0b64a9375 289 Gene3D G3DSA:3.40.50.1820 6 280 3.2E-51 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS17170 90225f86e20e8127cd43e6e0b64a9375 289 PRINTS PR00412 Epoxide hydrolase signature 61 76 4.7E-7 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS17170 90225f86e20e8127cd43e6e0b64a9375 289 PRINTS PR00412 Epoxide hydrolase signature 106 119 4.7E-7 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS17170 90225f86e20e8127cd43e6e0b64a9375 289 PRINTS PR00412 Epoxide hydrolase signature 260 282 4.7E-7 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS17170 90225f86e20e8127cd43e6e0b64a9375 289 PRINTS PR00412 Epoxide hydrolase signature 120 133 4.7E-7 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS17170 90225f86e20e8127cd43e6e0b64a9375 289 PRINTS PR00111 Alpha/beta hydrolase fold signature 120 133 2.3E-6 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS17170 90225f86e20e8127cd43e6e0b64a9375 289 PRINTS PR00111 Alpha/beta hydrolase fold signature 106 119 2.3E-6 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS17170 90225f86e20e8127cd43e6e0b64a9375 289 PRINTS PR00111 Alpha/beta hydrolase fold signature 230 244 2.3E-6 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS17170 90225f86e20e8127cd43e6e0b64a9375 289 PRINTS PR00111 Alpha/beta hydrolase fold signature 61 76 2.3E-6 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS17170 90225f86e20e8127cd43e6e0b64a9375 289 SUPERFAMILY SSF53474 7 283 1.91E-49 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS06375 ed5263eefe41773c474621b350af27f8 513 SUPERFAMILY SSF49363 39 142 8.89E-12 T 29-03-2018 IPR008963 Purple acid phosphatase-like, N-terminal GO:0003993|GO:0046872 SMALA_RS06375 ed5263eefe41773c474621b350af27f8 513 Pfam PF16656 Purple acid Phosphatase, N-terminal domain 50 142 4.3E-17 T 29-03-2018 IPR015914 Purple acid phosphatase, N-terminal GO:0003993|GO:0046872 SMALA_RS06375 ed5263eefe41773c474621b350af27f8 513 Gene3D G3DSA:2.60.40.380 49 145 1.4E-15 T 29-03-2018 SMALA_RS06375 ed5263eefe41773c474621b350af27f8 513 SUPERFAMILY SSF56300 149 404 1.22E-34 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SMALA_RS06375 ed5263eefe41773c474621b350af27f8 513 Gene3D G3DSA:3.60.21.10 146 507 5.3E-38 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SMALA_RS06375 ed5263eefe41773c474621b350af27f8 513 Pfam PF00149 Calcineurin-like phosphoesterase 150 351 6.9E-12 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 SMALA_RS25025 483dfd2745118f188dc6c06b320b0a07 89 Gene3D G3DSA:3.40.50.300 8 86 3.1E-4 T 29-03-2018 SMALA_RS00760 d8b995736f8a1d7d5da516e195a82faa 293 SUPERFAMILY SSF53474 5 292 1.97E-58 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS00760 d8b995736f8a1d7d5da516e195a82faa 293 PRINTS PR00412 Epoxide hydrolase signature 31 49 1.1E-19 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS00760 d8b995736f8a1d7d5da516e195a82faa 293 PRINTS PR00412 Epoxide hydrolase signature 51 66 1.1E-19 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS00760 d8b995736f8a1d7d5da516e195a82faa 293 PRINTS PR00412 Epoxide hydrolase signature 268 290 1.1E-19 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS00760 d8b995736f8a1d7d5da516e195a82faa 293 PRINTS PR00412 Epoxide hydrolase signature 97 110 1.1E-19 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS00760 d8b995736f8a1d7d5da516e195a82faa 293 Gene3D G3DSA:3.40.50.1820 3 293 6.2E-43 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS00760 d8b995736f8a1d7d5da516e195a82faa 293 Pfam PF00561 alpha/beta hydrolase fold 28 280 4.3E-17 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS15045 873c47c7773a9dbfc7b80b0730b63e24 110 Gene3D G3DSA:3.10.20.30 1 90 4.8E-22 T 29-03-2018 IPR012675 Beta-grasp domain SMALA_RS15045 873c47c7773a9dbfc7b80b0730b63e24 110 Pfam PF02597 ThiS family 5 90 1.5E-19 T 29-03-2018 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 SMALA_RS15045 873c47c7773a9dbfc7b80b0730b63e24 110 SUPERFAMILY SSF54285 1 90 2.18E-25 T 29-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp SMALA_RS05610 bae0afa52ddb2fb0d8fa850f2a4bd3c0 539 Gene3D G3DSA:3.40.50.1820 13 498 3.5E-45 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS05610 bae0afa52ddb2fb0d8fa850f2a4bd3c0 539 SUPERFAMILY SSF53474 174 266 8.82E-24 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS05610 bae0afa52ddb2fb0d8fa850f2a4bd3c0 539 SUPERFAMILY SSF53474 74 146 8.82E-24 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS05610 bae0afa52ddb2fb0d8fa850f2a4bd3c0 539 SUPERFAMILY SSF53474 378 482 8.82E-24 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS05610 bae0afa52ddb2fb0d8fa850f2a4bd3c0 539 Pfam PF08386 TAP-like protein 409 507 1.5E-21 T 29-03-2018 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal SMALA_RS05610 bae0afa52ddb2fb0d8fa850f2a4bd3c0 539 Pfam PF00561 alpha/beta hydrolase fold 101 277 5.9E-22 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS31945 fa38bf80a58e565f136967f84e49ff77 404 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 7 402 5.8E-133 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 SMALA_RS31945 fa38bf80a58e565f136967f84e49ff77 404 Gene3D G3DSA:3.40.47.10 1 277 2.4E-46 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS31945 fa38bf80a58e565f136967f84e49ff77 404 Gene3D G3DSA:3.40.47.10 278 404 1.3E-30 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS31945 fa38bf80a58e565f136967f84e49ff77 404 SUPERFAMILY SSF53901 3 277 9.27E-60 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS31945 fa38bf80a58e565f136967f84e49ff77 404 Pfam PF02803 Thiolase, C-terminal domain 282 403 2.1E-47 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 SMALA_RS31945 fa38bf80a58e565f136967f84e49ff77 404 PIRSF PIRSF000429 2 404 3.2E-108 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 SMALA_RS31945 fa38bf80a58e565f136967f84e49ff77 404 ProSitePatterns PS00099 Thiolases active site. 385 398 - T 29-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 SMALA_RS31945 fa38bf80a58e565f136967f84e49ff77 404 ProSitePatterns PS00737 Thiolases signature 2. 350 366 - T 29-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 SMALA_RS31945 fa38bf80a58e565f136967f84e49ff77 404 SUPERFAMILY SSF53901 282 403 2.96E-45 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS31945 fa38bf80a58e565f136967f84e49ff77 404 Pfam PF00108 Thiolase, N-terminal domain 7 230 3.6E-41 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 SMALA_RS07945 b663f41ffc7979b19da0d8f5ba1c3531 222 TIGRFAM TIGR00681 kdpC: K+-transporting ATPase, C subunit 14 216 8.7E-47 T 29-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 SMALA_RS07945 b663f41ffc7979b19da0d8f5ba1c3531 222 Pfam PF02669 K+-transporting ATPase, c chain 14 216 1.1E-63 T 29-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 SMALA_RS07945 b663f41ffc7979b19da0d8f5ba1c3531 222 PIRSF PIRSF001296 8 222 4.2E-67 T 29-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 SMALA_RS07945 b663f41ffc7979b19da0d8f5ba1c3531 222 Hamap MF_00276 Potassium-transporting ATPase KdpC subunit [kdpC]. 9 218 32.197 T 29-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 SMALA_RS20760 bd58ee3bf671641e4cdee2a95803a720 137 Gene3D G3DSA:1.25.40.10 31 137 1.1E-4 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS20760 bd58ee3bf671641e4cdee2a95803a720 137 PIRSF PIRSF017349 1 137 5.6E-67 T 29-03-2018 IPR014487 Protein of unknown function DUF3151 SMALA_RS20760 bd58ee3bf671641e4cdee2a95803a720 137 Pfam PF11349 Protein of unknown function (DUF3151) 10 134 6.8E-59 T 29-03-2018 IPR014487 Protein of unknown function DUF3151 SMALA_RS19595 f5876180d2e8d4133899f0e4922351b8 372 Gene3D G3DSA:3.40.630.30 187 346 1.3E-34 T 29-03-2018 SMALA_RS19595 f5876180d2e8d4133899f0e4922351b8 372 Pfam PF02388 FemAB family 8 248 3.2E-31 T 29-03-2018 IPR003447 FemABX peptidyl transferase GO:0016755|GO:0044038 SMALA_RS19595 f5876180d2e8d4133899f0e4922351b8 372 Pfam PF02388 FemAB family 265 365 3.4E-17 T 29-03-2018 IPR003447 FemABX peptidyl transferase GO:0016755|GO:0044038 SMALA_RS19595 f5876180d2e8d4133899f0e4922351b8 372 SUPERFAMILY SSF55729 5 114 4.93E-36 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS19595 f5876180d2e8d4133899f0e4922351b8 372 SUPERFAMILY SSF55729 143 194 4.93E-36 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS19595 f5876180d2e8d4133899f0e4922351b8 372 Gene3D G3DSA:3.40.630.30 3 186 3.6E-42 T 29-03-2018 SMALA_RS19595 f5876180d2e8d4133899f0e4922351b8 372 SUPERFAMILY SSF55729 183 365 2.12E-38 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS02255 b5f7686a1e03be0a64e6b69e38ec3341 306 Pfam PF00480 ROK family 4 302 5.7E-43 T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 SMALA_RS02255 b5f7686a1e03be0a64e6b69e38ec3341 306 Gene3D G3DSA:3.30.420.40 3 130 7.3E-21 T 29-03-2018 SMALA_RS02255 b5f7686a1e03be0a64e6b69e38ec3341 306 SUPERFAMILY SSF53067 4 303 2.43E-46 T 29-03-2018 SMALA_RS02255 b5f7686a1e03be0a64e6b69e38ec3341 306 Gene3D G3DSA:3.30.420.40 131 303 1.4E-43 T 29-03-2018 SMALA_RS35175 138c7362112527e13624555a6955bbe7 167 SUPERFAMILY SSF46785 7 144 1.9E-37 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS35175 138c7362112527e13624555a6955bbe7 167 Gene3D G3DSA:1.10.10.10 1 155 5.2E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS35175 138c7362112527e13624555a6955bbe7 167 Pfam PF01638 HxlR-like helix-turn-helix 20 104 1.3E-22 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type SMALA_RS13130 6ba32478971e767b79b8695e37d7e24f 106 SUPERFAMILY SSF141091 1 101 4.05E-30 T 29-03-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS13130 6ba32478971e767b79b8695e37d7e24f 106 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 103 21.665 T 29-03-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS13130 6ba32478971e767b79b8695e37d7e24f 106 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 101 1.9E-23 T 29-03-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS13130 6ba32478971e767b79b8695e37d7e24f 106 ProSitePatterns PS01169 Ribosomal protein L21 signature. 72 94 - T 29-03-2018 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS13130 6ba32478971e767b79b8695e37d7e24f 106 Pfam PF00829 Ribosomal prokaryotic L21 protein 2 101 6.5E-31 T 29-03-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS26745 e552aefb617116394465d832748fbb42 215 Pfam PF14016 Protein of unknown function (DUF4232) 80 208 2.9E-22 T 29-03-2018 IPR025326 Protein of unknown function DUF4232 SMALA_RS28265 c7312888aae9b2a152eace10d9856630 345 Pfam PF08402 TOBE domain 269 341 7.9E-9 T 29-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 SMALA_RS28265 c7312888aae9b2a152eace10d9856630 345 SUPERFAMILY SSF50331 238 342 2.89E-7 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal SMALA_RS28265 c7312888aae9b2a152eace10d9856630 345 SMART SM00382 28 211 6.4E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS28265 c7312888aae9b2a152eace10d9856630 345 Gene3D G3DSA:3.40.50.300 1 243 1.5E-67 T 29-03-2018 SMALA_RS28265 c7312888aae9b2a152eace10d9856630 345 Pfam PF00005 ABC transporter 19 161 1.9E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS28265 c7312888aae9b2a152eace10d9856630 345 SUPERFAMILY SSF52540 3 241 1.39E-76 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS28265 c7312888aae9b2a152eace10d9856630 345 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS38690 ea9e8b206abe3ae0e7edc82cd0e98cd7 308 Gene3D G3DSA:3.10.180.10 133 287 2.2E-25 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS38690 ea9e8b206abe3ae0e7edc82cd0e98cd7 308 SUPERFAMILY SSF54593 1 88 1.04E-9 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS38690 ea9e8b206abe3ae0e7edc82cd0e98cd7 308 Gene3D G3DSA:3.10.180.10 1 116 7.0E-7 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS38690 ea9e8b206abe3ae0e7edc82cd0e98cd7 308 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 144 254 2.9E-11 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMALA_RS38690 ea9e8b206abe3ae0e7edc82cd0e98cd7 308 SUPERFAMILY SSF54593 139 284 4.4E-30 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS25735 072a81333a91982413c57a5a9546967a 204 Gene3D G3DSA:3.40.50.2300 4 128 1.2E-36 T 29-03-2018 SMALA_RS25735 072a81333a91982413c57a5a9546967a 204 Pfam PF00072 Response regulator receiver domain 7 118 1.4E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS25735 072a81333a91982413c57a5a9546967a 204 SUPERFAMILY SSF52172 5 132 3.7E-32 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS25735 072a81333a91982413c57a5a9546967a 204 SMART SM00421 141 198 3.8E-19 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS25735 072a81333a91982413c57a5a9546967a 204 Pfam PF00196 Bacterial regulatory proteins, luxR family 143 198 3.2E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS25735 072a81333a91982413c57a5a9546967a 204 Gene3D G3DSA:1.10.10.10 129 204 1.2E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS25735 072a81333a91982413c57a5a9546967a 204 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 174 1.4E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS25735 072a81333a91982413c57a5a9546967a 204 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 174 186 1.4E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS25735 072a81333a91982413c57a5a9546967a 204 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 144 158 1.4E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS25735 072a81333a91982413c57a5a9546967a 204 SUPERFAMILY SSF46894 127 204 8.5E-19 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS25735 072a81333a91982413c57a5a9546967a 204 SMART SM00448 5 118 5.7E-28 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS28515 7c278bf4cd98d04d58e8a77e7f8f5481 523 Pfam PF05108 Type VII secretion system ESX-1, transport TM domain B 3 519 7.1E-88 T 29-03-2018 IPR007795 Type VII secretion system EccB SMALA_RS28515 7c278bf4cd98d04d58e8a77e7f8f5481 523 TIGRFAM TIGR03919 T7SS_EccB: type VII secretion protein EccB 4 451 3.0E-60 T 29-03-2018 IPR007795 Type VII secretion system EccB SMALA_RS17870 906d1cc3b2d4d4f9be1686d78d9f58a9 149 SUPERFAMILY SSF55811 15 147 1.16E-27 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMALA_RS17870 906d1cc3b2d4d4f9be1686d78d9f58a9 149 Gene3D G3DSA:3.90.79.10 11 149 9.7E-29 T 29-03-2018 SMALA_RS17870 906d1cc3b2d4d4f9be1686d78d9f58a9 149 Pfam PF00293 NUDIX domain 18 136 1.9E-16 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SMALA_RS17870 906d1cc3b2d4d4f9be1686d78d9f58a9 149 ProSitePatterns PS00893 Nudix box signature. 52 73 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 SMALA_RS20930 58100e6acd8144af5cf1c776c6f43f69 359 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 10 353 39.989 T 29-03-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 SMALA_RS20930 58100e6acd8144af5cf1c776c6f43f69 359 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 11 342 1.4E-124 T 29-03-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 SMALA_RS20930 58100e6acd8144af5cf1c776c6f43f69 359 SUPERFAMILY SSF55326 10 174 1.94E-43 T 29-03-2018 IPR016188 PurM-like, N-terminal domain SMALA_RS20930 58100e6acd8144af5cf1c776c6f43f69 359 Pfam PF02769 AIR synthase related protein, C-terminal domain 182 344 9.4E-30 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain SMALA_RS20930 58100e6acd8144af5cf1c776c6f43f69 359 Gene3D G3DSA:3.90.650.10 176 353 4.6E-55 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain SMALA_RS20930 58100e6acd8144af5cf1c776c6f43f69 359 SUPERFAMILY SSF56042 178 345 3.44E-51 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain SMALA_RS20930 58100e6acd8144af5cf1c776c6f43f69 359 Gene3D G3DSA:3.30.1330.10 33 166 3.4E-43 T 29-03-2018 IPR016188 PurM-like, N-terminal domain SMALA_RS20930 58100e6acd8144af5cf1c776c6f43f69 359 Pfam PF00586 AIR synthase related protein, N-terminal domain 65 169 1.5E-15 T 29-03-2018 IPR016188 PurM-like, N-terminal domain SMALA_RS21930 65178922dd18506c630ec68abf173fbf 178 Gene3D G3DSA:1.20.120.450 6 51 1.4E-4 T 29-03-2018 SMALA_RS21930 65178922dd18506c630ec68abf173fbf 178 Pfam PF12867 DinB superfamily 15 163 4.3E-22 T 29-03-2018 IPR024775 DinB-like domain SMALA_RS21930 65178922dd18506c630ec68abf173fbf 178 Gene3D G3DSA:1.20.120.450 55 176 8.3E-17 T 29-03-2018 SMALA_RS21930 65178922dd18506c630ec68abf173fbf 178 SUPERFAMILY SSF109854 68 152 3.11E-7 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes SMALA_RS00750 c6d61e1175bd69b2c509e5bc9c4a4c28 277 PIRSF PIRSF017393 11 277 2.5E-82 T 29-03-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type SMALA_RS00750 c6d61e1175bd69b2c509e5bc9c4a4c28 277 SUPERFAMILY SSF53335 27 257 1.61E-35 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS00750 c6d61e1175bd69b2c509e5bc9c4a4c28 277 Gene3D G3DSA:3.40.50.150 9 277 5.1E-39 T 29-03-2018 SMALA_RS00750 c6d61e1175bd69b2c509e5bc9c4a4c28 277 Pfam PF04672 S-adenosyl methyltransferase 22 277 4.8E-84 T 29-03-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type SMALA_RS42980 02706a3b063b56ad0253aea1f9021712 237 Gene3D G3DSA:3.40.1350.10 102 228 3.3E-24 T 29-03-2018 SMALA_RS42980 02706a3b063b56ad0253aea1f9021712 237 SUPERFAMILY SSF52980 117 224 1.98E-18 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 SMALA_RS42980 02706a3b063b56ad0253aea1f9021712 237 Pfam PF04471 Restriction endonuclease 110 220 5.9E-22 T 29-03-2018 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 SMALA_RS35305 523990e7fa92a5c0e6537996e747800e 129 PIRSF PIRSF028743 5 129 4.4E-31 T 29-03-2018 IPR008634 Gas vesicle protein GvpO GO:0031412 SMALA_RS35305 523990e7fa92a5c0e6537996e747800e 129 Pfam PF05800 Gas vesicle synthesis protein GvpO 36 125 1.4E-32 T 29-03-2018 IPR008634 Gas vesicle protein GvpO GO:0031412 SMALA_RS35360 23c8a2515238cfc1fad5a43104a2c1a8 150 Gene3D G3DSA:3.40.630.30 1 140 3.9E-23 T 29-03-2018 SMALA_RS35360 23c8a2515238cfc1fad5a43104a2c1a8 150 SUPERFAMILY SSF55729 3 130 5.06E-22 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS35360 23c8a2515238cfc1fad5a43104a2c1a8 150 Pfam PF00583 Acetyltransferase (GNAT) family 27 128 1.9E-13 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SMALA_RS03325 90160f18d76b57c592a94c7a86e2bc4e 520 Pfam PF00817 impB/mucB/samB family 10 157 5.8E-45 T 29-03-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 SMALA_RS03325 90160f18d76b57c592a94c7a86e2bc4e 520 Gene3D G3DSA:1.10.150.20 175 248 2.7E-17 T 29-03-2018 SMALA_RS03325 90160f18d76b57c592a94c7a86e2bc4e 520 Hamap MF_01113 DNA polymerase IV [dinB]. 4 352 34.947 T 29-03-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 SMALA_RS03325 90160f18d76b57c592a94c7a86e2bc4e 520 Gene3D G3DSA:3.30.70.270 117 174 2.2E-12 T 29-03-2018 SMALA_RS03325 90160f18d76b57c592a94c7a86e2bc4e 520 Gene3D G3DSA:3.30.70.270 43 116 3.7E-21 T 29-03-2018 SMALA_RS03325 90160f18d76b57c592a94c7a86e2bc4e 520 Pfam PF11799 impB/mucB/samB family C-terminal domain 239 346 2.1E-22 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 SMALA_RS03325 90160f18d76b57c592a94c7a86e2bc4e 520 SUPERFAMILY SSF100879 243 343 1.21E-25 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 SMALA_RS03325 90160f18d76b57c592a94c7a86e2bc4e 520 Gene3D G3DSA:3.30.1490.100 249 353 1.6E-27 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 SMALA_RS03325 90160f18d76b57c592a94c7a86e2bc4e 520 SUPERFAMILY SSF56672 6 239 1.87E-70 T 29-03-2018 SMALA_RS40575 d379cf49797a3d2586096de9d0846d74 366 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 259 343 7.0E-18 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMALA_RS40575 d379cf49797a3d2586096de9d0846d74 366 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 260 325 9.2E-15 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMALA_RS40575 d379cf49797a3d2586096de9d0846d74 366 ProSitePatterns PS00211 ABC transporters family signature. 181 195 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS40575 d379cf49797a3d2586096de9d0846d74 366 SUPERFAMILY SSF52540 58 327 7.61E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS40575 d379cf49797a3d2586096de9d0846d74 366 SMART SM00382 57 258 9.5E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS40575 d379cf49797a3d2586096de9d0846d74 366 Gene3D G3DSA:3.40.50.300 30 344 1.8E-67 T 29-03-2018 SMALA_RS40575 d379cf49797a3d2586096de9d0846d74 366 Pfam PF00005 ABC transporter 49 208 7.3E-26 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS09820 8cb5e2af8ca580f2dbfd8b0b60a6b655 300 SMART SM00382 37 227 8.3E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS09820 8cb5e2af8ca580f2dbfd8b0b60a6b655 300 Gene3D G3DSA:3.40.50.300 9 299 2.8E-57 T 29-03-2018 SMALA_RS09820 8cb5e2af8ca580f2dbfd8b0b60a6b655 300 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 237 258 8.3E-6 T 29-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal SMALA_RS09820 8cb5e2af8ca580f2dbfd8b0b60a6b655 300 SUPERFAMILY SSF52540 11 257 1.3E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS09820 8cb5e2af8ca580f2dbfd8b0b60a6b655 300 Pfam PF00005 ABC transporter 29 188 9.2E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS03200 09e2628b6e249cb652052f8b80e79706 134 SUPERFAMILY SSF159238 1 133 4.71E-35 T 29-03-2018 IPR023159 SO1590-like domain SMALA_RS03200 09e2628b6e249cb652052f8b80e79706 134 Pfam PF11528 Protein of unknown function (DUF3224) 6 132 1.7E-37 T 29-03-2018 IPR021607 Protein of unknown function DUF3224 SMALA_RS03200 09e2628b6e249cb652052f8b80e79706 134 Gene3D G3DSA:2.40.350.10 1 134 1.8E-39 T 29-03-2018 IPR023159 SO1590-like domain SMALA_RS18390 3f006e5ff01f1e272b957c9a5d1c87d9 359 SUPERFAMILY SSF51735 2 71 1.54E-60 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS18390 3f006e5ff01f1e272b957c9a5d1c87d9 359 SUPERFAMILY SSF51735 102 349 1.54E-60 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS18390 3f006e5ff01f1e272b957c9a5d1c87d9 359 Gene3D G3DSA:3.40.50.720 158 323 4.4E-28 T 29-03-2018 SMALA_RS18390 3f006e5ff01f1e272b957c9a5d1c87d9 359 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 103 332 7.5E-44 T 29-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 SMALA_RS18390 3f006e5ff01f1e272b957c9a5d1c87d9 359 Gene3D G3DSA:3.30.1780.10 1 157 1.3E-26 T 29-03-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 SMALA_RS18390 3f006e5ff01f1e272b957c9a5d1c87d9 359 PIRSF PIRSF001439 1 351 1.0E-55 T 29-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 SMALA_RS32140 90ac3d825b7a9566656a874a4dff8a77 397 SUPERFAMILY SSF56574 20 166 9.16E-13 T 29-03-2018 IPR023796 Serpin domain SMALA_RS32140 90ac3d825b7a9566656a874a4dff8a77 397 SUPERFAMILY SSF56574 274 389 2.23E-10 T 29-03-2018 IPR023796 Serpin domain SMALA_RS32140 90ac3d825b7a9566656a874a4dff8a77 397 Gene3D G3DSA:3.30.497.10 3 392 3.9E-33 T 29-03-2018 SMALA_RS32140 90ac3d825b7a9566656a874a4dff8a77 397 Pfam PF00079 Serpin (serine protease inhibitor) 23 165 5.4E-10 T 29-03-2018 IPR023796 Serpin domain SMALA_RS32140 90ac3d825b7a9566656a874a4dff8a77 397 Pfam PF00079 Serpin (serine protease inhibitor) 276 389 3.9E-6 T 29-03-2018 IPR023796 Serpin domain SMALA_RS33455 8d9e4d18eda02a2497944289b8817512 640 Pfam PF00005 ABC transporter 401 556 4.5E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS33455 8d9e4d18eda02a2497944289b8817512 640 ProSitePatterns PS00211 ABC transporters family signature. 528 542 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS33455 8d9e4d18eda02a2497944289b8817512 640 Gene3D G3DSA:1.20.1560.10 43 363 3.8E-15 T 29-03-2018 SMALA_RS33455 8d9e4d18eda02a2497944289b8817512 640 Gene3D G3DSA:3.40.50.300 373 639 7.0E-63 T 29-03-2018 SMALA_RS33455 8d9e4d18eda02a2497944289b8817512 640 SMART SM00382 410 609 7.6E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS33455 8d9e4d18eda02a2497944289b8817512 640 SUPERFAMILY SSF90123 49 348 3.4E-15 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMALA_RS33455 8d9e4d18eda02a2497944289b8817512 640 SUPERFAMILY SSF52540 378 633 9.4E-68 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS19735 8370a13a399fc899af3de5166bd21520 380 SUPERFAMILY SSF52540 256 361 1.02E-40 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS19735 8370a13a399fc899af3de5166bd21520 380 SUPERFAMILY SSF52540 1 227 1.02E-40 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS19735 8370a13a399fc899af3de5166bd21520 380 ProSitePatterns PS00618 RecF protein signature 2. 323 341 - T 29-03-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 SMALA_RS19735 8370a13a399fc899af3de5166bd21520 380 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 1 369 6.9E-126 T 29-03-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 SMALA_RS19735 8370a13a399fc899af3de5166bd21520 380 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 357 3.4E-19 T 29-03-2018 IPR003395 RecF/RecN/SMC, N-terminal SMALA_RS19735 8370a13a399fc899af3de5166bd21520 380 ProSitePatterns PS00617 RecF protein signature 1. 117 137 - T 29-03-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 SMALA_RS19735 8370a13a399fc899af3de5166bd21520 380 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 380 96.163 T 29-03-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 SMALA_RS19735 8370a13a399fc899af3de5166bd21520 380 Gene3D G3DSA:3.40.50.300 1 378 4.2E-29 T 29-03-2018 SMALA_RS28035 d06520601fd86c12829d6edec9c255e6 319 SUPERFAMILY SSF55797 199 318 3.53E-22 T 29-03-2018 IPR014044 CAP domain SMALA_RS28035 d06520601fd86c12829d6edec9c255e6 319 Gene3D G3DSA:3.40.33.10 192 315 2.1E-16 T 29-03-2018 IPR014044 CAP domain SMALA_RS28035 d06520601fd86c12829d6edec9c255e6 319 Pfam PF00188 Cysteine-rich secretory protein family 203 317 1.9E-20 T 29-03-2018 IPR014044 CAP domain SMALA_RS16650 e6c258f2fab66f44681fd5c5aec14bed 529 Gene3D G3DSA:3.20.20.240 4 523 5.2E-215 T 29-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMALA_RS16650 e6c258f2fab66f44681fd5c5aec14bed 529 SUPERFAMILY SSF51703 3 523 7.06E-203 T 29-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMALA_RS16650 e6c258f2fab66f44681fd5c5aec14bed 529 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 5 524 2.1E-228 T 29-03-2018 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMALA_RS16650 e6c258f2fab66f44681fd5c5aec14bed 529 Pfam PF01642 Methylmalonyl-CoA mutase 6 521 5.8E-217 T 29-03-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMALA_RS22660 0478ad6403b1f0167bc38c632efc622f 37 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 36 - T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS22660 0478ad6403b1f0167bc38c632efc622f 37 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 37 17.021 T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS22660 0478ad6403b1f0167bc38c632efc622f 37 Pfam PF00444 Ribosomal protein L36 1 37 4.6E-18 T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS22660 0478ad6403b1f0167bc38c632efc622f 37 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 9 37 2.0E-9 T 29-03-2018 SMALA_RS22660 0478ad6403b1f0167bc38c632efc622f 37 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 37 9.0E-22 T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS22660 0478ad6403b1f0167bc38c632efc622f 37 SUPERFAMILY SSF57840 1 37 3.53E-16 T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS36150 96e53a706e160b5c95df43fd78f6fd54 140 Gene3D G3DSA:2.40.40.10 8 139 1.3E-14 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain SMALA_RS36150 96e53a706e160b5c95df43fd78f6fd54 140 Pfam PF03330 Lytic transglycolase 11 137 1.9E-8 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain SMALA_RS36150 96e53a706e160b5c95df43fd78f6fd54 140 SUPERFAMILY SSF50685 7 137 4.53E-6 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain SMALA_RS42070 eef5d58933aaa7451db0ec7de42017b0 524 Pfam PF00501 AMP-binding enzyme 10 433 1.3E-61 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS42070 eef5d58933aaa7451db0ec7de42017b0 524 ProSitePatterns PS00455 Putative AMP-binding domain signature. 160 171 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS42070 eef5d58933aaa7451db0ec7de42017b0 524 Gene3D G3DSA:2.30.38.10 320 425 2.0E-13 T 29-03-2018 SMALA_RS42070 eef5d58933aaa7451db0ec7de42017b0 524 Gene3D G3DSA:3.30.300.30 426 524 2.4E-23 T 29-03-2018 SMALA_RS42070 eef5d58933aaa7451db0ec7de42017b0 524 Gene3D G3DSA:3.40.50.980 1 165 7.2E-33 T 29-03-2018 SMALA_RS42070 eef5d58933aaa7451db0ec7de42017b0 524 Gene3D G3DSA:3.40.50.980 166 319 1.1E-30 T 29-03-2018 SMALA_RS42070 eef5d58933aaa7451db0ec7de42017b0 524 SUPERFAMILY SSF56801 3 523 5.63E-107 T 29-03-2018 SMALA_RS30870 f6b552a27ad9e8d12d0ad4ab183e8c29 400 SUPERFAMILY SSF47203 243 397 7.48E-54 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMALA_RS30870 f6b552a27ad9e8d12d0ad4ab183e8c29 400 SUPERFAMILY SSF56645 9 252 2.23E-72 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMALA_RS30870 f6b552a27ad9e8d12d0ad4ab183e8c29 400 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 126 229 7.6E-22 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 SMALA_RS30870 f6b552a27ad9e8d12d0ad4ab183e8c29 400 Gene3D G3DSA:1.20.140.10 232 400 5.5E-53 T 29-03-2018 SMALA_RS30870 f6b552a27ad9e8d12d0ad4ab183e8c29 400 Gene3D G3DSA:2.40.110.10 125 231 1.0E-32 T 29-03-2018 SMALA_RS30870 f6b552a27ad9e8d12d0ad4ab183e8c29 400 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 11 122 2.3E-31 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS30870 f6b552a27ad9e8d12d0ad4ab183e8c29 400 Gene3D G3DSA:1.10.540.10 8 124 5.1E-33 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS30870 f6b552a27ad9e8d12d0ad4ab183e8c29 400 PIRSF PIRSF016578 5 397 2.4E-17 T 29-03-2018 SMALA_RS30870 f6b552a27ad9e8d12d0ad4ab183e8c29 400 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 244 393 1.6E-46 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMALA_RS37280 2959c5e72ff99a855ca6afe821faa784 480 Gene3D G3DSA:3.30.9.10 103 179 7.3E-12 T 29-03-2018 SMALA_RS37280 2959c5e72ff99a855ca6afe821faa784 480 SUPERFAMILY SSF51905 15 229 2.59E-45 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS37280 2959c5e72ff99a855ca6afe821faa784 480 SUPERFAMILY SSF51905 328 410 2.59E-45 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS37280 2959c5e72ff99a855ca6afe821faa784 480 SUPERFAMILY SSF54373 230 325 3.79E-8 T 29-03-2018 SMALA_RS37280 2959c5e72ff99a855ca6afe821faa784 480 Pfam PF01266 FAD dependent oxidoreductase 15 364 6.0E-59 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 SMALA_RS37280 2959c5e72ff99a855ca6afe821faa784 480 Gene3D G3DSA:3.40.50.720 4 102 2.7E-7 T 29-03-2018 SMALA_RS37280 2959c5e72ff99a855ca6afe821faa784 480 Gene3D G3DSA:3.30.9.10 180 324 1.2E-28 T 29-03-2018 SMALA_RS37280 2959c5e72ff99a855ca6afe821faa784 480 Pfam PF04324 BFD-like [2Fe-2S] binding domain 409 459 2.1E-11 T 29-03-2018 IPR007419 BFD-like [2Fe-2S]-binding domain SMALA_RS40780 a420cec29800a3ac45ab561e226f99e1 376 SUPERFAMILY SSF53383 24 374 1.51E-85 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS40780 a420cec29800a3ac45ab561e226f99e1 376 PIRSF PIRSF001434 1 376 7.0E-105 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 SMALA_RS40780 a420cec29800a3ac45ab561e226f99e1 376 Gene3D G3DSA:3.40.640.10 3 255 2.0E-48 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS40780 a420cec29800a3ac45ab561e226f99e1 376 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 199 213 - T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 SMALA_RS40780 a420cec29800a3ac45ab561e226f99e1 376 Gene3D G3DSA:3.90.1150.10 256 376 1.4E-24 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS40780 a420cec29800a3ac45ab561e226f99e1 376 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 14 344 2.3E-94 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 SMALA_RS41725 788267723cb889f4bf998a83a59fe283 270 SUPERFAMILY SSF161098 5 256 7.46E-31 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS41725 788267723cb889f4bf998a83a59fe283 270 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 86 256 2.7E-9 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS41725 788267723cb889f4bf998a83a59fe283 270 Gene3D G3DSA:1.10.3720.10 8 270 1.4E-28 T 29-03-2018 SMALA_RS31510 11bc2cde36455460e748c90706cc4a06 247 SMART SM00460 81 159 1.5E-10 T 29-03-2018 IPR002931 Transglutaminase-like SMALA_RS31510 11bc2cde36455460e748c90706cc4a06 247 SUPERFAMILY SSF54001 30 180 5.56E-17 T 29-03-2018 SMALA_RS31510 11bc2cde36455460e748c90706cc4a06 247 Pfam PF01841 Transglutaminase-like superfamily 35 157 3.7E-17 T 29-03-2018 IPR002931 Transglutaminase-like SMALA_RS01175 f627cfa1dd965f7e4d03806e0dba8c26 399 SUPERFAMILY SSF103473 4 392 1.14E-50 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS01175 f627cfa1dd965f7e4d03806e0dba8c26 399 Gene3D G3DSA:1.20.1250.20 209 399 1.3E-14 T 29-03-2018 SMALA_RS01175 f627cfa1dd965f7e4d03806e0dba8c26 399 Gene3D G3DSA:1.20.1250.20 7 199 1.5E-27 T 29-03-2018 SMALA_RS01175 f627cfa1dd965f7e4d03806e0dba8c26 399 Pfam PF07690 Major Facilitator Superfamily 20 296 2.6E-29 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS09230 949f190ff12be201c0fdf2c1881628af 297 Pfam PF04542 Sigma-70 region 2 95 160 4.3E-10 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS09230 949f190ff12be201c0fdf2c1881628af 297 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 88 243 6.7E-49 T 29-03-2018 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 SMALA_RS09230 949f190ff12be201c0fdf2c1881628af 297 Gene3D G3DSA:1.10.10.10 187 267 2.3E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS09230 949f190ff12be201c0fdf2c1881628af 297 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 91 242 8.5E-15 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS09230 949f190ff12be201c0fdf2c1881628af 297 SUPERFAMILY SSF88659 186 243 3.49E-11 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS09230 949f190ff12be201c0fdf2c1881628af 297 SUPERFAMILY SSF88946 89 175 4.71E-13 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS09230 949f190ff12be201c0fdf2c1881628af 297 Gene3D G3DSA:1.10.1740.10 70 177 2.6E-15 T 29-03-2018 SMALA_RS09230 949f190ff12be201c0fdf2c1881628af 297 Pfam PF08281 Sigma-70, region 4 189 239 1.5E-12 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS07765 25c0098a6094405b0a2a8cd4865a3543 394 Gene3D G3DSA:3.30.390.10 12 151 2.4E-19 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMALA_RS07765 25c0098a6094405b0a2a8cd4865a3543 394 SUPERFAMILY SSF51604 135 376 5.75E-37 T 29-03-2018 IPR029065 Enolase C-terminal domain-like SMALA_RS07765 25c0098a6094405b0a2a8cd4865a3543 394 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 66 146 1.3E-8 T 29-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain SMALA_RS07765 25c0098a6094405b0a2a8cd4865a3543 394 Gene3D G3DSA:3.20.20.120 152 377 4.7E-36 T 29-03-2018 IPR029065 Enolase C-terminal domain-like SMALA_RS07765 25c0098a6094405b0a2a8cd4865a3543 394 Pfam PF13378 Enolase C-terminal domain-like 171 376 3.2E-29 T 29-03-2018 IPR029065 Enolase C-terminal domain-like SMALA_RS07765 25c0098a6094405b0a2a8cd4865a3543 394 SMART SM00922 165 266 6.9E-4 T 29-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal SMALA_RS07765 25c0098a6094405b0a2a8cd4865a3543 394 SUPERFAMILY SSF54826 54 146 6.72E-12 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMALA_RS19465 5f44480842ac4899142fc6af180bfce1 64 Pfam PF17260 Family of unknown function (DUF5326) 4 63 3.2E-29 T 29-03-2018 IPR020246 Uncharacterised protein family SCO3924 SMALA_RS19465 5f44480842ac4899142fc6af180bfce1 64 ProDom PD267558 MEMBRANE TRANSMEMBRANE SPANNING SCO3924 4 62 6.0E-10 T 29-03-2018 IPR020246 Uncharacterised protein family SCO3924 SMALA_RS22280 8acd8e50081e106c9aff653605beee6b 321 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 3 320 21.941 T 29-03-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS22280 8acd8e50081e106c9aff653605beee6b 321 Pfam PF00146 NADH dehydrogenase 11 313 1.7E-98 T 29-03-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS11885 412849a35ac507b98bd702ba73b514a1 230 Pfam PF01596 O-methyltransferase 22 218 2.7E-54 T 29-03-2018 IPR002935 O-methyltransferase, family 3 GO:0008171 SMALA_RS11885 412849a35ac507b98bd702ba73b514a1 230 Gene3D G3DSA:3.40.50.150 1 219 8.1E-38 T 29-03-2018 SMALA_RS11885 412849a35ac507b98bd702ba73b514a1 230 SUPERFAMILY SSF53335 10 218 6.43E-43 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS41700 8b05c0540a8fb8b9e9dba58f529fb48d 690 Gene3D G3DSA:3.40.720.10 115 443 1.6E-19 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 SMALA_RS41700 8b05c0540a8fb8b9e9dba58f529fb48d 690 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 25 49 0.0014 T 29-03-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal SMALA_RS41700 8b05c0540a8fb8b9e9dba58f529fb48d 690 Pfam PF05506 Domain of unknown function (DUF756) 618 686 2.1E-7 T 29-03-2018 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 SMALA_RS41700 8b05c0540a8fb8b9e9dba58f529fb48d 690 Pfam PF05506 Domain of unknown function (DUF756) 511 589 5.6E-10 T 29-03-2018 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 SMALA_RS41700 8b05c0540a8fb8b9e9dba58f529fb48d 690 Pfam PF04185 Phosphoesterase family 73 440 3.7E-80 T 29-03-2018 IPR007312 Phosphoesterase GO:0016788 SMALA_RS10815 9a49c3b84a7da67211285fb0c44c45f8 196 Gene3D G3DSA:1.10.10.10 88 196 7.4E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS10815 9a49c3b84a7da67211285fb0c44c45f8 196 SMART SM00862 118 192 1.3E-22 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS10815 9a49c3b84a7da67211285fb0c44c45f8 196 Pfam PF00486 Transcriptional regulatory protein, C terminal 118 191 3.4E-23 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS10815 9a49c3b84a7da67211285fb0c44c45f8 196 SUPERFAMILY SSF46894 105 193 3.4E-26 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS09300 1ae2ccaf0df91a4d57d3d25cd68d2fe2 406 Gene3D G3DSA:2.160.20.10 33 393 3.1E-50 T 29-03-2018 IPR012334 Pectin lyase fold SMALA_RS09300 1ae2ccaf0df91a4d57d3d25cd68d2fe2 406 SUPERFAMILY SSF51126 43 352 1.82E-52 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor SMALA_RS09300 1ae2ccaf0df91a4d57d3d25cd68d2fe2 406 SMART SM00710 217 239 150.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat SMALA_RS09300 1ae2ccaf0df91a4d57d3d25cd68d2fe2 406 SMART SM00710 184 214 760.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat SMALA_RS09300 1ae2ccaf0df91a4d57d3d25cd68d2fe2 406 SMART SM00710 136 158 2400.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat SMALA_RS09300 1ae2ccaf0df91a4d57d3d25cd68d2fe2 406 SMART SM00710 241 275 4300.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat SMALA_RS09300 1ae2ccaf0df91a4d57d3d25cd68d2fe2 406 SMART SM00710 159 181 860.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat SMALA_RS09300 1ae2ccaf0df91a4d57d3d25cd68d2fe2 406 Pfam PF07602 Protein of unknown function (DUF1565) 53 92 7.6E-5 T 29-03-2018 IPR011459 Domain of unknown function DUF1565 SMALA_RS09300 1ae2ccaf0df91a4d57d3d25cd68d2fe2 406 Pfam PF13229 Right handed beta helix region 133 307 2.6E-10 T 29-03-2018 SMALA_RS12675 391109e6de0ac414de2568479110aaeb 457 Pfam PF07690 Major Facilitator Superfamily 10 410 3.9E-44 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS12675 391109e6de0ac414de2568479110aaeb 457 Gene3D G3DSA:1.20.1250.20 4 194 4.4E-29 T 29-03-2018 SMALA_RS12675 391109e6de0ac414de2568479110aaeb 457 SUPERFAMILY SSF103473 246 451 7.32E-56 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS12675 391109e6de0ac414de2568479110aaeb 457 SUPERFAMILY SSF103473 4 195 7.32E-56 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS12675 391109e6de0ac414de2568479110aaeb 457 Gene3D G3DSA:1.20.1250.20 258 455 1.9E-13 T 29-03-2018 SMALA_RS22845 be540305c3f8d963044da91fc0fd50f0 287 SUPERFAMILY SSF46785 5 87 8.65E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS22845 be540305c3f8d963044da91fc0fd50f0 287 Gene3D G3DSA:1.10.10.10 1 86 3.3E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS22845 be540305c3f8d963044da91fc0fd50f0 287 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 1.8E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS22845 be540305c3f8d963044da91fc0fd50f0 287 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 1.8E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS22845 be540305c3f8d963044da91fc0fd50f0 287 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 1.8E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS22845 be540305c3f8d963044da91fc0fd50f0 287 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 65 4.8E-21 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS22845 be540305c3f8d963044da91fc0fd50f0 287 SUPERFAMILY SSF53850 95 282 8.99E-20 T 29-03-2018 SMALA_RS22845 be540305c3f8d963044da91fc0fd50f0 287 Gene3D G3DSA:3.40.190.10 95 185 2.1E-18 T 29-03-2018 SMALA_RS22845 be540305c3f8d963044da91fc0fd50f0 287 Pfam PF03466 LysR substrate binding domain 95 283 5.4E-19 T 29-03-2018 IPR005119 LysR, substrate-binding SMALA_RS22845 be540305c3f8d963044da91fc0fd50f0 287 Gene3D G3DSA:3.40.190.10 186 264 6.8E-6 T 29-03-2018 SMALA_RS22975 ba2777626a668e677b43150bc9ae35dd 385 Pfam PF06723 MreB/Mbl protein 263 369 5.0E-37 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 SMALA_RS22975 ba2777626a668e677b43150bc9ae35dd 385 Pfam PF06723 MreB/Mbl protein 10 221 1.4E-100 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 SMALA_RS22975 ba2777626a668e677b43150bc9ae35dd 385 SUPERFAMILY SSF53067 151 360 8.03E-39 T 29-03-2018 SMALA_RS22975 ba2777626a668e677b43150bc9ae35dd 385 Gene3D G3DSA:3.30.420.40 288 351 4.0E-9 T 29-03-2018 SMALA_RS22975 ba2777626a668e677b43150bc9ae35dd 385 Gene3D G3DSA:3.30.420.40 158 192 1.7E-4 T 29-03-2018 SMALA_RS22975 ba2777626a668e677b43150bc9ae35dd 385 Gene3D G3DSA:3.30.420.40 7 157 9.1E-41 T 29-03-2018 SMALA_RS22975 ba2777626a668e677b43150bc9ae35dd 385 SUPERFAMILY SSF53067 10 146 1.7E-42 T 29-03-2018 SMALA_RS22975 ba2777626a668e677b43150bc9ae35dd 385 Gene3D G3DSA:3.90.640.10 193 287 2.8E-30 T 29-03-2018 SMALA_RS22975 ba2777626a668e677b43150bc9ae35dd 385 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 67 90 1.3E-41 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 SMALA_RS22975 ba2777626a668e677b43150bc9ae35dd 385 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 130 149 1.3E-41 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 SMALA_RS22975 ba2777626a668e677b43150bc9ae35dd 385 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 185 205 1.3E-41 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 SMALA_RS22975 ba2777626a668e677b43150bc9ae35dd 385 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 47 65 1.3E-41 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 SMALA_RS22055 fda73460e0506d7a9c2cdea2b30dff37 67 SUPERFAMILY SSF50249 1 65 1.24E-25 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMALA_RS22055 fda73460e0506d7a9c2cdea2b30dff37 67 PIRSF PIRSF002599 1 67 5.3E-26 T 29-03-2018 IPR012156 Cold shock, CspA GO:0003676 SMALA_RS22055 fda73460e0506d7a9c2cdea2b30dff37 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 2.0E-31 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMALA_RS22055 fda73460e0506d7a9c2cdea2b30dff37 67 Gene3D G3DSA:2.40.50.140 1 67 4.5E-29 T 29-03-2018 SMALA_RS22055 fda73460e0506d7a9c2cdea2b30dff37 67 SMART SM00357 3 67 4.2E-31 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 SMALA_RS22055 fda73460e0506d7a9c2cdea2b30dff37 67 PRINTS PR00050 Cold shock protein signature 25 34 6.3E-18 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMALA_RS22055 fda73460e0506d7a9c2cdea2b30dff37 67 PRINTS PR00050 Cold shock protein signature 4 19 6.3E-18 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMALA_RS22055 fda73460e0506d7a9c2cdea2b30dff37 67 PRINTS PR00050 Cold shock protein signature 40 58 6.3E-18 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMALA_RS22055 fda73460e0506d7a9c2cdea2b30dff37 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 29-03-2018 IPR019844 Cold-shock conserved site SMALA_RS22935 b463331a499e6e8f68fbd3b8d9398769 306 Pfam PF03466 LysR substrate binding domain 89 304 5.2E-40 T 29-03-2018 IPR005119 LysR, substrate-binding SMALA_RS22935 b463331a499e6e8f68fbd3b8d9398769 306 SUPERFAMILY SSF53850 91 302 1.33E-34 T 29-03-2018 SMALA_RS22935 b463331a499e6e8f68fbd3b8d9398769 306 Gene3D G3DSA:3.40.190.10 90 189 5.4E-24 T 29-03-2018 SMALA_RS22935 b463331a499e6e8f68fbd3b8d9398769 306 SUPERFAMILY SSF46785 2 112 3.54E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS22935 b463331a499e6e8f68fbd3b8d9398769 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 2.1E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS22935 b463331a499e6e8f68fbd3b8d9398769 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 2.1E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS22935 b463331a499e6e8f68fbd3b8d9398769 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 2.1E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS22935 b463331a499e6e8f68fbd3b8d9398769 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 1.5E-22 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS22935 b463331a499e6e8f68fbd3b8d9398769 306 Gene3D G3DSA:1.10.10.10 1 84 7.5E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS22935 b463331a499e6e8f68fbd3b8d9398769 306 Gene3D G3DSA:3.40.190.10 190 278 1.5E-24 T 29-03-2018 SMALA_RS26890 e72ee4b23d85d1d1f9506a363d276b93 269 Gene3D G3DSA:1.20.120.220 96 268 2.6E-33 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMALA_RS26890 e72ee4b23d85d1d1f9506a363d276b93 269 Pfam PF00119 ATP synthase A chain 48 261 1.1E-48 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMALA_RS26890 e72ee4b23d85d1d1f9506a363d276b93 269 Hamap MF_01393 ATP synthase subunit a [atpB]. 27 268 12.618 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMALA_RS26890 e72ee4b23d85d1d1f9506a363d276b93 269 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 28 263 1.6E-41 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMALA_RS26890 e72ee4b23d85d1d1f9506a363d276b93 269 ProSitePatterns PS00449 ATP synthase a subunit signature. 193 202 - T 29-03-2018 IPR023011 ATP synthase, F0 complex, subunit A, active site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMALA_RS26890 e72ee4b23d85d1d1f9506a363d276b93 269 SUPERFAMILY SSF81336 97 261 7.72E-34 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMALA_RS26890 e72ee4b23d85d1d1f9506a363d276b93 269 PRINTS PR00123 ATP synthase A subunit signature 190 212 1.0E-15 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMALA_RS26890 e72ee4b23d85d1d1f9506a363d276b93 269 PRINTS PR00123 ATP synthase A subunit signature 105 121 1.0E-15 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMALA_RS26890 e72ee4b23d85d1d1f9506a363d276b93 269 PRINTS PR00123 ATP synthase A subunit signature 248 263 1.0E-15 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMALA_RS23115 78d1405304f9a886e5e9b32da00815a4 160 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 44 154 6.7E-28 T 29-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 SMALA_RS23115 78d1405304f9a886e5e9b32da00815a4 160 Pfam PF04075 F420H(2)-dependent quinone reductase 35 151 8.3E-26 T 29-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 SMALA_RS23115 78d1405304f9a886e5e9b32da00815a4 160 SUPERFAMILY SSF50475 51 143 6.04E-6 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS23115 78d1405304f9a886e5e9b32da00815a4 160 Gene3D G3DSA:2.30.110.10 19 157 2.2E-37 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS36455 dd8220da7107133fa66c712cee05725e 154 Gene3D G3DSA:3.40.1490.10 22 152 6.6E-39 T 29-03-2018 IPR023476 Peptidyl-tRNA hydrolase II domain MetaCyc: PWY-6308 SMALA_RS36455 dd8220da7107133fa66c712cee05725e 154 SUPERFAMILY SSF102462 21 154 5.75E-32 T 29-03-2018 IPR023476 Peptidyl-tRNA hydrolase II domain MetaCyc: PWY-6308 SMALA_RS36455 dd8220da7107133fa66c712cee05725e 154 PIRSF PIRSF033736 15 154 5.2E-31 T 29-03-2018 IPR017021 Uncharacterised conserved protein UCP033763 SMALA_RS36455 dd8220da7107133fa66c712cee05725e 154 Pfam PF09391 Protein of unknown function (DUF2000) 23 154 5.7E-43 T 29-03-2018 IPR018988 Protein of unknown function DUF2000 SMALA_RS40785 78f83e59994e068cf36ee9ee6bc9e034 386 SUPERFAMILY SSF55031 142 249 8.64E-20 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain SMALA_RS40785 78f83e59994e068cf36ee9ee6bc9e034 386 Gene3D G3DSA:3.40.630.10 1 238 6.5E-41 T 29-03-2018 SMALA_RS40785 78f83e59994e068cf36ee9ee6bc9e034 386 Pfam PF07687 Peptidase dimerisation domain 142 235 6.6E-10 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain SMALA_RS40785 78f83e59994e068cf36ee9ee6bc9e034 386 Gene3D G3DSA:3.40.630.10 245 365 3.0E-15 T 29-03-2018 SMALA_RS40785 78f83e59994e068cf36ee9ee6bc9e034 386 PIRSF PIRSF037226 1 368 7.9E-114 T 29-03-2018 IPR017144 Peptidase M20A, amidohydrolase, predicted SMALA_RS40785 78f83e59994e068cf36ee9ee6bc9e034 386 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 2 313 6.2E-61 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 SMALA_RS40785 78f83e59994e068cf36ee9ee6bc9e034 386 SUPERFAMILY SSF53187 258 350 7.07E-49 T 29-03-2018 SMALA_RS40785 78f83e59994e068cf36ee9ee6bc9e034 386 SUPERFAMILY SSF53187 2 157 7.07E-49 T 29-03-2018 SMALA_RS38055 0754b2a03b34b24d3665af2b6c985b7e 244 Gene3D G3DSA:3.40.50.1820 2 244 1.1E-20 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS38055 0754b2a03b34b24d3665af2b6c985b7e 244 Pfam PF12697 Alpha/beta hydrolase family 5 238 6.2E-16 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS38055 0754b2a03b34b24d3665af2b6c985b7e 244 SUPERFAMILY SSF53474 4 242 7.31E-24 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS28105 d0ce857617baa6c2677ecd428a482590 112 SUPERFAMILY SSF54913 2 112 8.58E-41 T 29-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta SMALA_RS28105 d0ce857617baa6c2677ecd428a482590 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 2.4E-39 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 SMALA_RS28105 d0ce857617baa6c2677ecd428a482590 112 PRINTS PR00340 P-II protein signature 2 17 8.7E-37 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 SMALA_RS28105 d0ce857617baa6c2677ecd428a482590 112 PRINTS PR00340 P-II protein signature 52 75 8.7E-37 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 SMALA_RS28105 d0ce857617baa6c2677ecd428a482590 112 PRINTS PR00340 P-II protein signature 23 41 8.7E-37 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 SMALA_RS28105 d0ce857617baa6c2677ecd428a482590 112 PRINTS PR00340 P-II protein signature 83 103 8.7E-37 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 SMALA_RS28105 d0ce857617baa6c2677ecd428a482590 112 Gene3D G3DSA:3.30.70.120 1 109 4.3E-45 T 29-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal SMALA_RS28105 d0ce857617baa6c2677ecd428a482590 112 SMART SM00938 4 105 1.1E-56 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 SMALA_RS28105 d0ce857617baa6c2677ecd428a482590 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 29-03-2018 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 SMALA_RS07375 3275f4bbbacc187df921d06ed29cb61c 321 Pfam PF00248 Aldo/keto reductase family 10 307 1.2E-42 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS07375 3275f4bbbacc187df921d06ed29cb61c 321 Gene3D G3DSA:3.20.20.100 1 310 2.2E-59 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS07375 3275f4bbbacc187df921d06ed29cb61c 321 SUPERFAMILY SSF51430 1 307 4.58E-61 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS04495 09f3a1f4a122fe32c67b2c4ba3f5e33c 226 SUPERFAMILY SSF56784 5 193 1.08E-54 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS04495 09f3a1f4a122fe32c67b2c4ba3f5e33c 226 Gene3D G3DSA:1.10.150.240 31 75 3.3E-18 T 29-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 SMALA_RS04495 09f3a1f4a122fe32c67b2c4ba3f5e33c 226 Gene3D G3DSA:3.40.50.1000 5 30 0.054 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS04495 09f3a1f4a122fe32c67b2c4ba3f5e33c 226 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 41 186 6.6E-19 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMALA_RS04495 09f3a1f4a122fe32c67b2c4ba3f5e33c 226 Gene3D G3DSA:3.40.50.1000 76 203 3.7E-30 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS04495 09f3a1f4a122fe32c67b2c4ba3f5e33c 226 Pfam PF13419 Haloacid dehalogenase-like hydrolase 7 186 8.6E-35 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS04495 09f3a1f4a122fe32c67b2c4ba3f5e33c 226 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 148 168 9.0E-9 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMALA_RS04495 09f3a1f4a122fe32c67b2c4ba3f5e33c 226 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 130 146 9.0E-9 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMALA_RS04495 09f3a1f4a122fe32c67b2c4ba3f5e33c 226 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 4 15 9.0E-9 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMALA_RS04495 09f3a1f4a122fe32c67b2c4ba3f5e33c 226 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 99 112 9.0E-9 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMALA_RS35030 3098382d590a4b96cd3d6fb25c071281 339 SUPERFAMILY SSF51430 20 331 4.06E-82 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS35030 3098382d590a4b96cd3d6fb25c071281 339 PRINTS PR00069 Aldo-keto reductase signature 148 165 3.0E-8 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMALA_RS35030 3098382d590a4b96cd3d6fb25c071281 339 PRINTS PR00069 Aldo-keto reductase signature 117 135 3.0E-8 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMALA_RS35030 3098382d590a4b96cd3d6fb25c071281 339 PRINTS PR00069 Aldo-keto reductase signature 53 77 3.0E-8 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMALA_RS35030 3098382d590a4b96cd3d6fb25c071281 339 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 148 165 - T 29-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 SMALA_RS35030 3098382d590a4b96cd3d6fb25c071281 339 Pfam PF00248 Aldo/keto reductase family 29 326 3.6E-65 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS35030 3098382d590a4b96cd3d6fb25c071281 339 Gene3D G3DSA:3.20.20.100 25 339 4.2E-82 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS19485 f26366705a6d280c16c4f55187bf1f9e 387 Gene3D G3DSA:3.40.640.10 4 247 9.4E-44 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS19485 f26366705a6d280c16c4f55187bf1f9e 387 SUPERFAMILY SSF53383 31 372 8.39E-86 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS19485 f26366705a6d280c16c4f55187bf1f9e 387 Gene3D G3DSA:3.90.1150.10 249 386 1.7E-33 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS19485 f26366705a6d280c16c4f55187bf1f9e 387 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 37 370 6.3E-82 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 SMALA_RS19485 f26366705a6d280c16c4f55187bf1f9e 387 PIRSF PIRSF001434 3 374 6.6E-106 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 SMALA_RS34715 9b8ec0d69f2ab6ca679eddb8c2625568 272 SUPERFAMILY SSF52540 23 239 2.18E-67 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS34715 9b8ec0d69f2ab6ca679eddb8c2625568 272 Gene3D G3DSA:3.40.50.300 19 261 2.9E-60 T 29-03-2018 SMALA_RS34715 9b8ec0d69f2ab6ca679eddb8c2625568 272 Pfam PF00005 ABC transporter 40 186 1.4E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS34715 9b8ec0d69f2ab6ca679eddb8c2625568 272 SMART SM00382 49 241 5.0E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS18520 0a53325dd47f0375d8714ff65ecb182a 812 PIRSF PIRSF001265 21 763 1.9E-259 T 29-03-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 SMALA_RS18520 0a53325dd47f0375d8714ff65ecb182a 812 Pfam PF03030 Inorganic H+ pyrophosphatase 37 750 3.3E-235 T 29-03-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 SMALA_RS18520 0a53325dd47f0375d8714ff65ecb182a 812 Hamap MF_01129 Putative K(+)-stimulated pyrophosphate-energized sodium pump [hppA]. 26 755 24.354 T 29-03-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 SMALA_RS04010 5e323bbee049efe5cb1a6b407c6abc76 527 SUPERFAMILY SSF56112 8 298 3.78E-68 T 29-03-2018 IPR011009 Protein kinase-like domain SMALA_RS04010 5e323bbee049efe5cb1a6b407c6abc76 527 SMART SM00220 14 277 1.4E-55 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMALA_RS04010 5e323bbee049efe5cb1a6b407c6abc76 527 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 20 43 - T 29-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 SMALA_RS04010 5e323bbee049efe5cb1a6b407c6abc76 527 Gene3D G3DSA:3.30.200.20 4 102 1.8E-21 T 29-03-2018 SMALA_RS04010 5e323bbee049efe5cb1a6b407c6abc76 527 Pfam PF00069 Protein kinase domain 14 269 2.8E-44 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMALA_RS04010 5e323bbee049efe5cb1a6b407c6abc76 527 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 137 149 - T 29-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMALA_RS04010 5e323bbee049efe5cb1a6b407c6abc76 527 Gene3D G3DSA:1.10.510.10 103 324 1.6E-44 T 29-03-2018 SMALA_RS26875 2c188f3ef5507665a7f6afd1d3b7408e 429 SUPERFAMILY SSF53383 12 414 1.39E-142 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS26875 2c188f3ef5507665a7f6afd1d3b7408e 429 Gene3D G3DSA:3.90.1150.10 278 413 9.2E-40 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS26875 2c188f3ef5507665a7f6afd1d3b7408e 429 Gene3D G3DSA:3.40.640.10 42 277 5.3E-51 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS26875 2c188f3ef5507665a7f6afd1d3b7408e 429 Pfam PF00464 Serine hydroxymethyltransferase 14 388 5.6E-129 T 29-03-2018 SMALA_RS26875 2c188f3ef5507665a7f6afd1d3b7408e 429 PIRSF PIRSF000412 7 418 1.2E-142 T 29-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 SMALA_RS26875 2c188f3ef5507665a7f6afd1d3b7408e 429 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 12 414 44.145 T 29-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 SMALA_RS10265 f2b1f6850192c352a12af088e8506a58 350 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 47 176 7.6E-65 T 29-03-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 SMALA_RS10265 f2b1f6850192c352a12af088e8506a58 350 SUPERFAMILY SSF52540 16 291 9.47E-43 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS10265 f2b1f6850192c352a12af088e8506a58 350 Gene3D G3DSA:1.10.8.300 208 316 3.1E-32 T 29-03-2018 SMALA_RS10265 f2b1f6850192c352a12af088e8506a58 350 PIRSF PIRSF002849 2 321 4.2E-132 T 29-03-2018 SMALA_RS10265 f2b1f6850192c352a12af088e8506a58 350 Gene3D G3DSA:3.40.50.300 18 194 8.3E-27 T 29-03-2018 SMALA_RS04020 bcaa5125de65ba0648f8a16481a3655c 357 ProSitePatterns PS00356 LacI-type HTH domain signature. 23 41 - T 29-03-2018 SMALA_RS04020 bcaa5125de65ba0648f8a16481a3655c 357 Pfam PF13377 Periplasmic binding protein-like domain 187 346 1.0E-30 T 29-03-2018 SMALA_RS04020 bcaa5125de65ba0648f8a16481a3655c 357 SUPERFAMILY SSF53822 77 341 1.18E-61 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SMALA_RS04020 bcaa5125de65ba0648f8a16481a3655c 357 Gene3D G3DSA:3.40.50.2300 75 192 7.1E-33 T 29-03-2018 SMALA_RS04020 bcaa5125de65ba0648f8a16481a3655c 357 SUPERFAMILY SSF47413 20 78 1.53E-15 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS04020 bcaa5125de65ba0648f8a16481a3655c 357 Gene3D G3DSA:1.10.260.40 22 74 1.3E-21 T 29-03-2018 SMALA_RS04020 bcaa5125de65ba0648f8a16481a3655c 357 SMART SM00354 20 90 6.2E-24 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS04020 bcaa5125de65ba0648f8a16481a3655c 357 Gene3D G3DSA:3.40.50.2300 193 326 2.9E-37 T 29-03-2018 SMALA_RS04020 bcaa5125de65ba0648f8a16481a3655c 357 Pfam PF00356 Bacterial regulatory proteins, lacI family 22 67 4.9E-13 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS08880 86c68965fd25be23e2baed610487a85b 385 Pfam PF13185 GAF domain 27 170 1.4E-17 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS08880 86c68965fd25be23e2baed610487a85b 385 SMART SM00387 291 385 1.6E-10 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS08880 86c68965fd25be23e2baed610487a85b 385 Gene3D G3DSA:3.30.565.10 169 384 2.6E-24 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS08880 86c68965fd25be23e2baed610487a85b 385 SUPERFAMILY SSF55874 256 383 3.54E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS08880 86c68965fd25be23e2baed610487a85b 385 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 294 383 2.5E-7 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS08880 86c68965fd25be23e2baed610487a85b 385 Gene3D G3DSA:3.30.450.40 23 168 2.9E-31 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS08880 86c68965fd25be23e2baed610487a85b 385 SMART SM00065 28 180 1.9E-16 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS08880 86c68965fd25be23e2baed610487a85b 385 Pfam PF07730 Histidine kinase 187 254 1.5E-17 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMALA_RS08880 86c68965fd25be23e2baed610487a85b 385 PRINTS PR00344 Bacterial sensor protein C-terminal signature 327 341 2.4E-5 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS08880 86c68965fd25be23e2baed610487a85b 385 PRINTS PR00344 Bacterial sensor protein C-terminal signature 370 383 2.4E-5 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS08880 86c68965fd25be23e2baed610487a85b 385 PRINTS PR00344 Bacterial sensor protein C-terminal signature 346 364 2.4E-5 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMALA_RS08880 86c68965fd25be23e2baed610487a85b 385 SUPERFAMILY SSF55781 18 183 1.31E-28 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS08180 43e0e3f424d933efe394a210813e4aa5 393 SUPERFAMILY SSF51569 8 391 6.74E-135 T 29-03-2018 SMALA_RS08180 43e0e3f424d933efe394a210813e4aa5 393 Gene3D G3DSA:3.20.20.70 169 326 1.8E-6 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS08180 43e0e3f424d933efe394a210813e4aa5 393 Gene3D G3DSA:3.20.20.390 18 168 0.33 T 29-03-2018 SMALA_RS08180 43e0e3f424d933efe394a210813e4aa5 393 Pfam PF01474 Class-II DAHP synthetase family 176 382 2.8E-72 T 29-03-2018 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 SMALA_RS08180 43e0e3f424d933efe394a210813e4aa5 393 Pfam PF01474 Class-II DAHP synthetase family 9 169 7.9E-49 T 29-03-2018 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 SMALA_RS07810 dffc5b61380b21cee0b74c68ff9fa847 905 SUPERFAMILY SSF52540 312 447 1.97E-9 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS07810 dffc5b61380b21cee0b74c68ff9fa847 905 SUPERFAMILY SSF56436 662 891 9.65E-46 T 29-03-2018 IPR016187 C-type lectin fold SMALA_RS07810 dffc5b61380b21cee0b74c68ff9fa847 905 Pfam PF05729 NACHT domain 317 446 3.3E-8 T 29-03-2018 SMALA_RS07810 dffc5b61380b21cee0b74c68ff9fa847 905 Gene3D G3DSA:3.90.1580.10 670 904 1.7E-42 T 29-03-2018 SMALA_RS07810 dffc5b61380b21cee0b74c68ff9fa847 905 Pfam PF03781 Sulfatase-modifying factor enzyme 1 674 888 3.9E-32 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 SMALA_RS07810 dffc5b61380b21cee0b74c68ff9fa847 905 SMART SM00382 313 457 9.0E-5 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS07810 dffc5b61380b21cee0b74c68ff9fa847 905 Gene3D G3DSA:3.40.50.300 49 461 4.4E-11 T 29-03-2018 SMALA_RS35500 44fd19e9c1eb2efbb0f804f455a58842 252 SUPERFAMILY SSF117396 1 239 1.44E-73 T 29-03-2018 IPR002763 Protein of unknown function DUF72 SMALA_RS35500 44fd19e9c1eb2efbb0f804f455a58842 252 Gene3D G3DSA:3.20.20.410 1 246 8.7E-76 T 29-03-2018 IPR002763 Protein of unknown function DUF72 SMALA_RS35500 44fd19e9c1eb2efbb0f804f455a58842 252 Pfam PF01904 Protein of unknown function DUF72 20 237 2.0E-55 T 29-03-2018 IPR002763 Protein of unknown function DUF72 SMALA_RS35390 cb52b43109884d17ce8b364f9c89bca7 804 PIRSF PIRSF036289 1 802 2.1E-208 T 29-03-2018 IPR017045 Maltose phosphorylase/glycosyl hydrolase/vacuolar acid trehalase SMALA_RS35390 cb52b43109884d17ce8b364f9c89bca7 804 Gene3D G3DSA:1.50.10.10 313 716 8.9E-104 T 29-03-2018 SMALA_RS35390 cb52b43109884d17ce8b364f9c89bca7 804 Gene3D G3DSA:2.60.420.10 717 794 1.8E-11 T 29-03-2018 SMALA_RS35390 cb52b43109884d17ce8b364f9c89bca7 804 Pfam PF03632 Glycosyl hydrolase family 65 central catalytic domain 319 731 6.6E-146 T 29-03-2018 IPR005195 Glycoside hydrolase, family 65, central catalytic GO:0003824|GO:0005975 SMALA_RS35390 cb52b43109884d17ce8b364f9c89bca7 804 SUPERFAMILY SSF74650 2 268 4.71E-59 T 29-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 SMALA_RS35390 cb52b43109884d17ce8b364f9c89bca7 804 Gene3D G3DSA:2.70.98.40 1 270 3.9E-77 T 29-03-2018 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 SMALA_RS35390 cb52b43109884d17ce8b364f9c89bca7 804 SUPERFAMILY SSF48208 272 782 4.99E-100 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 SMALA_RS35390 cb52b43109884d17ce8b364f9c89bca7 804 Pfam PF03633 Glycosyl hydrolase family 65, C-terminal domain 741 791 7.2E-9 T 29-03-2018 IPR005194 Glycoside hydrolase family 65, C-terminal SMALA_RS35390 cb52b43109884d17ce8b364f9c89bca7 804 Pfam PF03636 Glycosyl hydrolase family 65, N-terminal domain 8 266 4.7E-67 T 29-03-2018 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 SMALA_RS19265 e50507ed66b1f0699d29f770ecd2e1bb 498 SMART SM01011 63 204 8.8E-41 T 29-03-2018 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 SMALA_RS19265 e50507ed66b1f0699d29f770ecd2e1bb 498 Gene3D G3DSA:3.90.230.10 225 498 3.8E-70 T 29-03-2018 SMALA_RS19265 e50507ed66b1f0699d29f770ecd2e1bb 498 Pfam PF05195 Aminopeptidase P, N-terminal domain 70 189 1.3E-19 T 29-03-2018 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 SMALA_RS19265 e50507ed66b1f0699d29f770ecd2e1bb 498 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 406 418 - T 29-03-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site SMALA_RS19265 e50507ed66b1f0699d29f770ecd2e1bb 498 SUPERFAMILY SSF53092 63 230 9.94E-28 T 29-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal SMALA_RS19265 e50507ed66b1f0699d29f770ecd2e1bb 498 Gene3D G3DSA:3.40.350.10 61 224 1.2E-34 T 29-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal SMALA_RS19265 e50507ed66b1f0699d29f770ecd2e1bb 498 SUPERFAMILY SSF55920 231 493 1.7E-67 T 29-03-2018 IPR000994 Peptidase M24 SMALA_RS19265 e50507ed66b1f0699d29f770ecd2e1bb 498 Pfam PF00557 Metallopeptidase family M24 239 472 8.5E-49 T 29-03-2018 IPR000994 Peptidase M24 SMALA_RS09160 07b37ab124e5157f611da3aa594fe41f 215 SMART SM01007 10 183 8.7E-60 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal SMALA_RS09160 07b37ab124e5157f611da3aa594fe41f 215 Gene3D G3DSA:3.40.225.10 3 215 2.7E-63 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal SMALA_RS09160 07b37ab124e5157f611da3aa594fe41f 215 SUPERFAMILY SSF53639 6 214 1.04E-63 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal SMALA_RS09160 07b37ab124e5157f611da3aa594fe41f 215 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 11 183 1.3E-48 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal SMALA_RS28760 8038ca6af5a7a4f94bf285f5457ab521 128 SMART SM00530 11 66 4.5E-8 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS28760 8038ca6af5a7a4f94bf285f5457ab521 128 Pfam PF13560 Helix-turn-helix domain 8 65 1.4E-10 T 29-03-2018 SMALA_RS28760 8038ca6af5a7a4f94bf285f5457ab521 128 SUPERFAMILY SSF47413 3 72 1.46E-12 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS28760 8038ca6af5a7a4f94bf285f5457ab521 128 Gene3D G3DSA:1.10.260.40 2 77 3.7E-13 T 29-03-2018 SMALA_RS07190 a8398bd6e239761a4780e9c6e9e37fe8 320 Pfam PF00902 Sec-independent protein translocase protein (TatC) 20 247 7.2E-58 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 SMALA_RS07190 a8398bd6e239761a4780e9c6e9e37fe8 320 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 8 266 16.649 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 SMALA_RS07190 a8398bd6e239761a4780e9c6e9e37fe8 320 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 129 155 3.2E-35 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 SMALA_RS07190 a8398bd6e239761a4780e9c6e9e37fe8 320 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 111 129 3.2E-35 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 SMALA_RS07190 a8398bd6e239761a4780e9c6e9e37fe8 320 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 179 207 3.2E-35 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 SMALA_RS07190 a8398bd6e239761a4780e9c6e9e37fe8 320 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 17 44 3.2E-35 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 SMALA_RS07190 a8398bd6e239761a4780e9c6e9e37fe8 320 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 18 252 3.7E-53 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 SMALA_RS08735 2b4c3de1c787b08fc3e81e094edf1899 390 Pfam PF16483 Beta-1,3-glucanase 40 387 5.7E-99 T 29-03-2018 IPR032477 Beta-1,3-glucanase, N-terminal KEGG: 00500+3.2.1.39 SMALA_RS15285 59318ea19aa906cbd97f220ae093ec66 231 Pfam PF13419 Haloacid dehalogenase-like hydrolase 17 196 6.7E-17 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS15285 59318ea19aa906cbd97f220ae093ec66 231 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 110 191 5.0E-6 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMALA_RS15285 59318ea19aa906cbd97f220ae093ec66 231 SUPERFAMILY SSF56784 14 226 5.56E-33 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS15285 59318ea19aa906cbd97f220ae093ec66 231 Gene3D G3DSA:3.40.50.1000 76 230 2.9E-28 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS11965 6d49b39c823f1850f1251cb67f9c266a 401 SUPERFAMILY SSF53474 207 349 7.85E-7 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS11965 6d49b39c823f1850f1251cb67f9c266a 401 Gene3D G3DSA:3.40.50.1820 163 386 2.2E-16 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS11965 6d49b39c823f1850f1251cb67f9c266a 401 Pfam PF06259 Alpha/beta hydrolase 162 335 2.1E-54 T 29-03-2018 IPR010427 Protein of unknown function DUF1023 SMALA_RS21945 b8acb4e67ac3f6a339faf35ac79b2447 232 SUPERFAMILY SSF53254 13 205 5.13E-37 T 29-03-2018 IPR029033 Histidine phosphatase superfamily SMALA_RS21945 b8acb4e67ac3f6a339faf35ac79b2447 232 Gene3D G3DSA:3.40.50.1240 12 219 2.8E-31 T 29-03-2018 IPR029033 Histidine phosphatase superfamily SMALA_RS21945 b8acb4e67ac3f6a339faf35ac79b2447 232 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 16 202 8.3E-36 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SMALA_RS21945 b8acb4e67ac3f6a339faf35ac79b2447 232 SMART SM00855 14 166 2.6E-15 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SMALA_RS40400 63dc128e9c146a0bbaae64a41b8143fc 310 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 97 298 3.3E-18 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS40400 63dc128e9c146a0bbaae64a41b8143fc 310 Gene3D G3DSA:1.10.3720.10 70 306 2.5E-43 T 29-03-2018 SMALA_RS40400 63dc128e9c146a0bbaae64a41b8143fc 310 Gene3D G3DSA:1.20.58.370 9 52 3.5E-4 T 29-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain SMALA_RS40400 63dc128e9c146a0bbaae64a41b8143fc 310 SUPERFAMILY SSF161098 63 295 1.05E-56 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS36565 5404fd1c78bb2fb8b856ec64ba31293b 124 Gene3D G3DSA:3.30.450.30 1 124 7.4E-17 T 29-03-2018 SMALA_RS37865 b856d78fb78ffebd7c71f6f814c1a19d 339 Gene3D G3DSA:3.40.366.10 17 333 1.9E-31 T 29-03-2018 SMALA_RS37865 b856d78fb78ffebd7c71f6f814c1a19d 339 SUPERFAMILY SSF52151 220 318 1.49E-31 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS37865 b856d78fb78ffebd7c71f6f814c1a19d 339 SUPERFAMILY SSF52151 23 149 1.49E-31 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS32210 f965d6835fbd6d31ecf88d6be8ed5f13 321 Gene3D G3DSA:3.40.630.30 146 278 2.4E-22 T 29-03-2018 SMALA_RS32210 f965d6835fbd6d31ecf88d6be8ed5f13 321 SUPERFAMILY SSF55729 127 273 6.73E-22 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS32210 f965d6835fbd6d31ecf88d6be8ed5f13 321 Pfam PF00583 Acetyltransferase (GNAT) family 186 269 2.0E-8 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SMALA_RS16690 2204163be5f89e987979bebbdd722636 156 Gene3D G3DSA:1.20.1300.10 24 152 2.3E-23 T 29-03-2018 SMALA_RS16690 2204163be5f89e987979bebbdd722636 156 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 39 142 5.6E-17 T 29-03-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMALA_RS16690 2204163be5f89e987979bebbdd722636 156 SUPERFAMILY SSF81343 31 153 1.11E-31 T 29-03-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMALA_RS07145 681ec0e93fef7e7a319bf1274993830d 245 SUPERFAMILY SSF53807 6 241 5.49E-31 T 29-03-2018 SMALA_RS07145 681ec0e93fef7e7a319bf1274993830d 245 Gene3D G3DSA:3.40.50.1980 84 245 2.2E-16 T 29-03-2018 SMALA_RS07145 681ec0e93fef7e7a319bf1274993830d 245 Gene3D G3DSA:3.40.50.1980 4 83 3.2E-14 T 29-03-2018 SMALA_RS42465 ad6d659bf11455cbedc50b5612ff1f48 288 Gene3D G3DSA:3.40.50.1820 3 277 7.5E-32 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS42465 ad6d659bf11455cbedc50b5612ff1f48 288 Pfam PF12697 Alpha/beta hydrolase family 7 273 2.3E-22 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS42465 ad6d659bf11455cbedc50b5612ff1f48 288 SUPERFAMILY SSF53474 6 275 5.73E-34 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS18035 acc37daeb9af544faf538384aa61bbd2 398 SUPERFAMILY SSF55874 270 394 5.42E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS18035 acc37daeb9af544faf538384aa61bbd2 398 Pfam PF07730 Histidine kinase 187 252 3.9E-21 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMALA_RS18035 acc37daeb9af544faf538384aa61bbd2 398 Gene3D G3DSA:3.30.565.10 215 395 8.9E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS36440 ea4c0be800580da9ef89e05b355b4af9 305 SUPERFAMILY SSF54427 6 138 1.28E-32 T 29-03-2018 IPR032710 NTF2-like domain SMALA_RS36440 ea4c0be800580da9ef89e05b355b4af9 305 Gene3D G3DSA:3.10.450.50 2 138 1.4E-27 T 29-03-2018 SMALA_RS36440 ea4c0be800580da9ef89e05b355b4af9 305 Pfam PF07366 SnoaL-like polyketide cyclase 10 132 2.1E-29 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain SMALA_RS36440 ea4c0be800580da9ef89e05b355b4af9 305 Gene3D G3DSA:2.30.110.10 139 298 7.1E-41 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS36440 ea4c0be800580da9ef89e05b355b4af9 305 Pfam PF01613 Flavin reductase like domain 155 296 9.6E-34 T 29-03-2018 IPR002563 Flavin reductase like domain GO:0010181 SMALA_RS36440 ea4c0be800580da9ef89e05b355b4af9 305 SUPERFAMILY SSF50475 146 295 4.71E-45 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS36440 ea4c0be800580da9ef89e05b355b4af9 305 SMART SM00903 154 296 1.1E-51 T 29-03-2018 IPR002563 Flavin reductase like domain GO:0010181 SMALA_RS10385 f0b5cf879dcfec6633e7dfed83f9f0a8 171 ProSitePatterns PS00549 Bacterioferritin signature. 1 19 - T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 SMALA_RS10385 f0b5cf879dcfec6633e7dfed83f9f0a8 171 TIGRFAM TIGR00754 bfr: bacterioferritin 1 156 3.6E-62 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 SMALA_RS10385 f0b5cf879dcfec6633e7dfed83f9f0a8 171 SUPERFAMILY SSF47240 1 156 2.96E-45 T 29-03-2018 IPR009078 Ferritin-like superfamily SMALA_RS10385 f0b5cf879dcfec6633e7dfed83f9f0a8 171 Gene3D G3DSA:1.20.5.420 85 138 2.6E-14 T 29-03-2018 SMALA_RS10385 f0b5cf879dcfec6633e7dfed83f9f0a8 171 Pfam PF00210 Ferritin-like domain 9 143 1.1E-30 T 29-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 SMALA_RS10385 f0b5cf879dcfec6633e7dfed83f9f0a8 171 PRINTS PR00601 Bacterioferritin signature 23 43 2.6E-53 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 SMALA_RS10385 f0b5cf879dcfec6633e7dfed83f9f0a8 171 PRINTS PR00601 Bacterioferritin signature 44 64 2.6E-53 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 SMALA_RS10385 f0b5cf879dcfec6633e7dfed83f9f0a8 171 PRINTS PR00601 Bacterioferritin signature 65 85 2.6E-53 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 SMALA_RS10385 f0b5cf879dcfec6633e7dfed83f9f0a8 171 PRINTS PR00601 Bacterioferritin signature 86 106 2.6E-53 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 SMALA_RS10385 f0b5cf879dcfec6633e7dfed83f9f0a8 171 PRINTS PR00601 Bacterioferritin signature 3 22 2.6E-53 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 SMALA_RS10385 f0b5cf879dcfec6633e7dfed83f9f0a8 171 PRINTS PR00601 Bacterioferritin signature 128 149 2.6E-53 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 SMALA_RS10385 f0b5cf879dcfec6633e7dfed83f9f0a8 171 PRINTS PR00601 Bacterioferritin signature 107 127 2.6E-53 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 SMALA_RS10385 f0b5cf879dcfec6633e7dfed83f9f0a8 171 PIRSF PIRSF002560 1 157 4.9E-63 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 SMALA_RS10385 f0b5cf879dcfec6633e7dfed83f9f0a8 171 Gene3D G3DSA:1.20.1260.10 1 75 8.5E-17 T 29-03-2018 IPR012347 Ferritin-related SMALA_RS28685 de99be9f9cd62a516a9f221f3b9f95fd 561 SMART SM00849 31 225 5.8E-22 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS28685 de99be9f9cd62a516a9f221f3b9f95fd 561 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 20 558 1.8E-150 T 29-03-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 SMALA_RS28685 de99be9f9cd62a516a9f221f3b9f95fd 561 Pfam PF00753 Metallo-beta-lactamase superfamily 28 174 2.6E-13 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS28685 de99be9f9cd62a516a9f221f3b9f95fd 561 Hamap MF_01491 Ribonuclease J [rnj]. 14 561 40.731 T 29-03-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 SMALA_RS28685 de99be9f9cd62a516a9f221f3b9f95fd 561 SUPERFAMILY SSF56281 19 433 1.06E-96 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS28685 de99be9f9cd62a516a9f221f3b9f95fd 561 PIRSF PIRSF004803 13 561 1.4E-204 T 29-03-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 SMALA_RS28685 de99be9f9cd62a516a9f221f3b9f95fd 561 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 370 411 1.2E-9 T 29-03-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain SMALA_RS28685 de99be9f9cd62a516a9f221f3b9f95fd 561 Gene3D G3DSA:3.60.15.10 11 457 5.2E-66 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS30500 48198ad77b3c38902883d6d974553dd8 254 SUPERFAMILY SSF55486 36 203 1.26E-8 T 29-03-2018 SMALA_RS30500 48198ad77b3c38902883d6d974553dd8 254 Gene3D G3DSA:3.40.190.10 8 235 5.2E-5 T 29-03-2018 SMALA_RS30500 48198ad77b3c38902883d6d974553dd8 254 Pfam PF04228 Putative neutral zinc metallopeptidase 75 245 1.8E-9 T 29-03-2018 IPR007343 Uncharacterised protein family, zinc metallopeptidase putative SMALA_RS01240 b6cb950240c32248e99c62161c0e6f9b 315 Pfam PF13229 Right handed beta helix region 110 287 3.0E-10 T 29-03-2018 SMALA_RS01240 b6cb950240c32248e99c62161c0e6f9b 315 SUPERFAMILY SSF51126 53 300 8.53E-23 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor SMALA_RS01240 b6cb950240c32248e99c62161c0e6f9b 315 SMART SM00710 254 276 420.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat SMALA_RS01240 b6cb950240c32248e99c62161c0e6f9b 315 SMART SM00710 137 162 0.46 T 29-03-2018 IPR006626 Parallel beta-helix repeat SMALA_RS01240 b6cb950240c32248e99c62161c0e6f9b 315 SMART SM00710 278 302 5100.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat SMALA_RS01240 b6cb950240c32248e99c62161c0e6f9b 315 Gene3D G3DSA:2.160.20.10 61 307 4.7E-24 T 29-03-2018 IPR012334 Pectin lyase fold SMALA_RS39920 9bac91106a62865a3247dc1fdca70f0b 246 Pfam PF08241 Methyltransferase domain 55 148 9.2E-19 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 SMALA_RS39920 9bac91106a62865a3247dc1fdca70f0b 246 SUPERFAMILY SSF53335 8 223 1.69E-35 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS39920 9bac91106a62865a3247dc1fdca70f0b 246 Gene3D G3DSA:3.40.50.150 34 225 2.7E-33 T 29-03-2018 SMALA_RS39180 b38fd0e6bab8f9ebe32ec116ce7b5f0c 382 SUPERFAMILY SSF55909 3 381 4.46E-71 T 29-03-2018 SMALA_RS39180 b38fd0e6bab8f9ebe32ec116ce7b5f0c 382 Gene3D G3DSA:3.75.10.10 1 382 5.1E-60 T 29-03-2018 SMALA_RS34525 f4fbb1da33558169b008cfa3611e547d 188 SUPERFAMILY SSF69118 36 183 2.02E-36 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 SMALA_RS34525 f4fbb1da33558169b008cfa3611e547d 188 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 67 115 4.5E-20 T 29-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SMALA_RS34525 f4fbb1da33558169b008cfa3611e547d 188 Gene3D G3DSA:1.20.1290.10 37 184 2.4E-33 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 SMALA_RS34525 f4fbb1da33558169b008cfa3611e547d 188 Pfam PF02627 Carboxymuconolactone decarboxylase family 46 131 4.5E-21 T 29-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SMALA_RS14765 a95fb10fb53211ea9a16c0824838ad24 338 Gene3D G3DSA:3.90.180.10 1 161 1.1E-33 T 29-03-2018 SMALA_RS14765 a95fb10fb53211ea9a16c0824838ad24 338 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 137 1.3E-18 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS14765 a95fb10fb53211ea9a16c0824838ad24 338 Gene3D G3DSA:3.40.50.720 162 283 1.5E-19 T 29-03-2018 SMALA_RS14765 a95fb10fb53211ea9a16c0824838ad24 338 SUPERFAMILY SSF50129 1 176 3.5E-34 T 29-03-2018 IPR011032 GroES-like SMALA_RS14765 a95fb10fb53211ea9a16c0824838ad24 338 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 56 70 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 SMALA_RS14765 a95fb10fb53211ea9a16c0824838ad24 338 SUPERFAMILY SSF51735 145 302 3.23E-27 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS14765 a95fb10fb53211ea9a16c0824838ad24 338 Pfam PF00107 Zinc-binding dehydrogenase 179 297 1.6E-15 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMALA_RS23490 acc3298f6b259e090523e494a7008eb1 157 SUPERFAMILY SSF102405 2 153 5.68E-13 T 29-03-2018 SMALA_RS23490 acc3298f6b259e090523e494a7008eb1 157 Gene3D G3DSA:3.40.50.450 1 156 4.5E-31 T 29-03-2018 SMALA_RS25950 1de98010434631573ba517c5296ef342 599 Pfam PF13692 Glycosyl transferases group 1 324 483 4.3E-20 T 29-03-2018 SMALA_RS25950 1de98010434631573ba517c5296ef342 599 Gene3D G3DSA:3.40.50.2000 14 316 5.4E-6 T 29-03-2018 SMALA_RS25950 1de98010434631573ba517c5296ef342 599 SUPERFAMILY SSF53756 196 515 1.92E-53 T 29-03-2018 SMALA_RS25950 1de98010434631573ba517c5296ef342 599 SUPERFAMILY SSF53756 2 87 1.92E-53 T 29-03-2018 SMALA_RS25950 1de98010434631573ba517c5296ef342 599 Gene3D G3DSA:3.40.50.2000 317 503 5.5E-35 T 29-03-2018 SMALA_RS25950 1de98010434631573ba517c5296ef342 599 Pfam PF11997 Domain of unknown function (DUF3492) 1 294 1.3E-32 T 29-03-2018 IPR022622 Domain of unknown function DUF3492 SMALA_RS06195 bf69a867fbaf31f4cb0928d01e86b149 755 Pfam PF03176 MMPL family 45 379 1.1E-75 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 SMALA_RS06195 bf69a867fbaf31f4cb0928d01e86b149 755 Pfam PF03176 MMPL family 419 713 1.8E-35 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 SMALA_RS06195 bf69a867fbaf31f4cb0928d01e86b149 755 PRINTS PR00702 Acriflavin resistance protein family signature 176 199 5.4E-5 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SMALA_RS06195 bf69a867fbaf31f4cb0928d01e86b149 755 PRINTS PR00702 Acriflavin resistance protein family signature 304 327 5.4E-5 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SMALA_RS06195 bf69a867fbaf31f4cb0928d01e86b149 755 PRINTS PR00702 Acriflavin resistance protein family signature 229 253 5.4E-5 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 SMALA_RS06195 bf69a867fbaf31f4cb0928d01e86b149 755 Gene3D G3DSA:1.20.1640.10 472 709 3.1E-31 T 29-03-2018 SMALA_RS06195 bf69a867fbaf31f4cb0928d01e86b149 755 Gene3D G3DSA:1.20.1640.10 122 334 2.7E-35 T 29-03-2018 SMALA_RS06195 bf69a867fbaf31f4cb0928d01e86b149 755 SUPERFAMILY SSF82866 480 711 1.26E-27 T 29-03-2018 SMALA_RS06195 bf69a867fbaf31f4cb0928d01e86b149 755 SUPERFAMILY SSF82866 128 334 3.14E-32 T 29-03-2018 SMALA_RS01060 7d191db049f85076f82cf7e5c2052eef 316 SUPERFAMILY SSF53686 25 305 1.83E-67 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMALA_RS01060 7d191db049f85076f82cf7e5c2052eef 316 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 32 304 9.8E-62 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMALA_RS01060 7d191db049f85076f82cf7e5c2052eef 316 Gene3D G3DSA:3.40.50.1100 23 158 1.4E-36 T 29-03-2018 SMALA_RS01060 7d191db049f85076f82cf7e5c2052eef 316 Gene3D G3DSA:3.40.50.1100 159 316 1.2E-28 T 29-03-2018 SMALA_RS01765 fa02a5e8ee41bc70ecfbc8f6c450c2b1 239 TIGRFAM TIGR03943 TIGR03943: TIGR03943 family protein 23 233 1.1E-46 T 29-03-2018 IPR015402 Protein of unknown function DUF1980 SMALA_RS21385 82dbacdedf23743f318f978ad944deda 228 Gene3D G3DSA:1.20.120.20 3 151 6.7E-7 T 29-03-2018 SMALA_RS07260 09eff705829762f845d4eff2342a95f1 503 Pfam PF03136 Pup-ligase protein 5 457 3.3E-191 T 29-03-2018 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 SMALA_RS07260 09eff705829762f845d4eff2342a95f1 503 PIRSF PIRSF018077 10 500 2.8E-218 T 29-03-2018 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 SMALA_RS07260 09eff705829762f845d4eff2342a95f1 503 TIGRFAM TIGR03688 pupylate_PafA2: proteasome accessory factor PafA2 4 490 2.4E-244 T 29-03-2018 IPR022366 Pup deamidase GO:0008233|GO:0016811 SMALA_RS14085 7eda4b79ef325a34c52099719b16766e 386 SUPERFAMILY SSF103481 202 284 1.26E-8 T 29-03-2018 SMALA_RS14085 7eda4b79ef325a34c52099719b16766e 386 Pfam PF00892 EamA-like transporter family 6 130 2.2E-15 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SMALA_RS14085 7eda4b79ef325a34c52099719b16766e 386 Pfam PF00892 EamA-like transporter family 141 280 1.6E-13 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SMALA_RS14085 7eda4b79ef325a34c52099719b16766e 386 SUPERFAMILY SSF103481 35 134 4.84E-13 T 29-03-2018 SMALA_RS09720 f8042f446e1678b930255b00482cee95 202 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 5 186 3.5E-51 T 29-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 SMALA_RS09720 f8042f446e1678b930255b00482cee95 202 SUPERFAMILY SSF52540 1 191 2.62E-38 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS09720 f8042f446e1678b930255b00482cee95 202 Pfam PF01121 Dephospho-CoA kinase 4 179 1.3E-57 T 29-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 SMALA_RS09720 f8042f446e1678b930255b00482cee95 202 Gene3D G3DSA:3.40.50.300 1 202 2.8E-44 T 29-03-2018 SMALA_RS09720 f8042f446e1678b930255b00482cee95 202 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 1 196 27.219 T 29-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 SMALA_RS26925 4803fe4f229e3bf069240465a64b3eed 125 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 3 120 18.801 T 29-03-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMALA_RS26925 4803fe4f229e3bf069240465a64b3eed 125 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 18 90 2.0E-29 T 29-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMALA_RS26925 4803fe4f229e3bf069240465a64b3eed 125 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 5 114 3.7E-26 T 29-03-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMALA_RS26925 4803fe4f229e3bf069240465a64b3eed 125 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 5 84 3.1E-23 T 29-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMALA_RS26925 4803fe4f229e3bf069240465a64b3eed 125 SUPERFAMILY SSF51344 5 85 8.11E-21 T 29-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMALA_RS26925 4803fe4f229e3bf069240465a64b3eed 125 Gene3D G3DSA:2.60.15.10 1 90 2.6E-24 T 29-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SMALA_RS15840 e66f880dae0fa4a37549e1eb55526dd2 60 Pfam PF03966 Trm112p-like protein 7 47 1.4E-7 T 29-03-2018 IPR005651 Uncharacterised protein family UPF0434/Trm112 SMALA_RS15840 e66f880dae0fa4a37549e1eb55526dd2 60 Gene3D G3DSA:2.20.25.10 10 59 5.2E-22 T 29-03-2018 SMALA_RS15840 e66f880dae0fa4a37549e1eb55526dd2 60 SUPERFAMILY SSF158997 1 58 4.19E-16 T 29-03-2018 SMALA_RS25570 866e2373cad5bf9ef6761177847ef81e 547 PIRSF PIRSF002741 2 543 1.4E-72 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 SMALA_RS25570 866e2373cad5bf9ef6761177847ef81e 547 Gene3D G3DSA:3.90.76.10 60 186 4.1E-26 T 29-03-2018 SMALA_RS25570 866e2373cad5bf9ef6761177847ef81e 547 Gene3D G3DSA:3.40.190.10 187 322 1.3E-25 T 29-03-2018 SMALA_RS25570 866e2373cad5bf9ef6761177847ef81e 547 Gene3D G3DSA:3.10.105.10 323 515 5.6E-35 T 29-03-2018 SMALA_RS25570 866e2373cad5bf9ef6761177847ef81e 547 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 91 466 5.8E-56 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain SMALA_RS25570 866e2373cad5bf9ef6761177847ef81e 547 SUPERFAMILY SSF53850 40 545 8.14E-94 T 29-03-2018 SMALA_RS23350 e32fd9bd3357b7d52ffd5e2946432096 103 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 38 53 4.9E-12 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS23350 e32fd9bd3357b7d52ffd5e2946432096 103 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 53 68 4.9E-12 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS23350 e32fd9bd3357b7d52ffd5e2946432096 103 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 6 21 4.9E-12 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS23350 e32fd9bd3357b7d52ffd5e2946432096 103 Gene3D G3DSA:1.10.10.10 2 103 5.7E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS23350 e32fd9bd3357b7d52ffd5e2946432096 103 Pfam PF12840 Helix-turn-helix domain 4 62 1.9E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS23350 e32fd9bd3357b7d52ffd5e2946432096 103 SUPERFAMILY SSF46785 3 94 1.08E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS23350 e32fd9bd3357b7d52ffd5e2946432096 103 SMART SM00418 4 85 6.2E-26 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS23800 e1355f3f26e2f3e8c12567c636b7d34d 174 SUPERFAMILY SSF55729 9 146 3.01E-22 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS23800 e1355f3f26e2f3e8c12567c636b7d34d 174 Gene3D G3DSA:3.40.630.30 1 166 3.7E-23 T 29-03-2018 SMALA_RS23800 e1355f3f26e2f3e8c12567c636b7d34d 174 Pfam PF00583 Acetyltransferase (GNAT) family 34 135 1.1E-10 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SMALA_RS01410 75ec4d581fff0f1d08ac32f0497a80f6 144 SUPERFAMILY SSF55961 3 129 9.47E-15 T 29-03-2018 SMALA_RS01410 75ec4d581fff0f1d08ac32f0497a80f6 144 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 5 126 1.4E-6 T 29-03-2018 IPR019587 Polyketide cyclase/dehydrase SMALA_RS01410 75ec4d581fff0f1d08ac32f0497a80f6 144 Gene3D G3DSA:3.30.530.20 1 144 1.1E-12 T 29-03-2018 IPR023393 START-like domain SMALA_RS24825 e59530b4a6849a38ff89d4f7a12a8900 303 SUPERFAMILY SSF53223 18 122 2.19E-25 T 29-03-2018 SMALA_RS24825 e59530b4a6849a38ff89d4f7a12a8900 303 SUPERFAMILY SSF51735 123 295 5.6E-37 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS24825 e59530b4a6849a38ff89d4f7a12a8900 303 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 17 296 27.754 T 29-03-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 SMALA_RS24825 e59530b4a6849a38ff89d4f7a12a8900 303 Gene3D G3DSA:3.40.50.720 133 298 9.3E-33 T 29-03-2018 SMALA_RS24825 e59530b4a6849a38ff89d4f7a12a8900 303 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 22 109 2.0E-22 T 29-03-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 SMALA_RS24825 e59530b4a6849a38ff89d4f7a12a8900 303 Gene3D G3DSA:3.40.50.10860 10 132 2.3E-37 T 29-03-2018 SMALA_RS12175 eeaf25b1a0973660b4c46cea1f9242d4 141 TIGRFAM TIGR03562 osmo_induc_OsmC: peroxiredoxin, OsmC subfamily 4 138 1.6E-52 T 29-03-2018 IPR019904 Peroxiredoxin OsmC GO:0004601|GO:0006979 KEGG: 00480+1.11.1.15 SMALA_RS12175 eeaf25b1a0973660b4c46cea1f9242d4 141 SUPERFAMILY SSF82784 1 131 2.49E-32 T 29-03-2018 IPR003718 OsmC/Ohr family SMALA_RS12175 eeaf25b1a0973660b4c46cea1f9242d4 141 Pfam PF02566 OsmC-like protein 44 136 4.0E-19 T 29-03-2018 IPR003718 OsmC/Ohr family SMALA_RS12175 eeaf25b1a0973660b4c46cea1f9242d4 141 Gene3D G3DSA:3.30.300.20 1 141 1.0E-28 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta SMALA_RS40635 a5068647f4478f61e0e12b2f9fb35e49 374 SUPERFAMILY SSF51126 13 348 1.83E-47 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor SMALA_RS40635 a5068647f4478f61e0e12b2f9fb35e49 374 Pfam PF13229 Right handed beta helix region 107 297 2.4E-10 T 29-03-2018 SMALA_RS40635 a5068647f4478f61e0e12b2f9fb35e49 374 Gene3D G3DSA:2.160.20.10 7 371 5.1E-40 T 29-03-2018 IPR012334 Pectin lyase fold SMALA_RS09490 b983ebcd07fd4723ccfd8a9dc8695854 308 SUPERFAMILY SSF52540 4 221 2.43E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS09490 b983ebcd07fd4723ccfd8a9dc8695854 308 Pfam PF00005 ABC transporter 23 161 1.5E-22 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS09490 b983ebcd07fd4723ccfd8a9dc8695854 308 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS09490 b983ebcd07fd4723ccfd8a9dc8695854 308 SMART SM00382 31 217 1.5E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS09490 b983ebcd07fd4723ccfd8a9dc8695854 308 Gene3D G3DSA:3.40.50.300 3 259 3.3E-60 T 29-03-2018 SMALA_RS15550 81a8cd2fdbefcaaa6861cbfb2eeeb724 564 Pfam PF00069 Protein kinase domain 11 271 5.4E-52 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMALA_RS15550 81a8cd2fdbefcaaa6861cbfb2eeeb724 564 Gene3D G3DSA:1.10.510.10 115 486 3.9E-57 T 29-03-2018 SMALA_RS15550 81a8cd2fdbefcaaa6861cbfb2eeeb724 564 SUPERFAMILY SSF56112 401 480 2.02E-79 T 29-03-2018 IPR011009 Protein kinase-like domain SMALA_RS15550 81a8cd2fdbefcaaa6861cbfb2eeeb724 564 SUPERFAMILY SSF56112 5 278 2.02E-79 T 29-03-2018 IPR011009 Protein kinase-like domain SMALA_RS15550 81a8cd2fdbefcaaa6861cbfb2eeeb724 564 Gene3D G3DSA:3.30.200.20 2 114 1.3E-22 T 29-03-2018 SMALA_RS15550 81a8cd2fdbefcaaa6861cbfb2eeeb724 564 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 138 150 - T 29-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMALA_RS15550 81a8cd2fdbefcaaa6861cbfb2eeeb724 564 SMART SM00220 8 278 1.4E-72 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMALA_RS39880 afb739b3b86e48f29895af965abaf07c 156 Pfam PF01047 MarR family 35 90 8.8E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS39880 afb739b3b86e48f29895af965abaf07c 156 Gene3D G3DSA:1.10.10.10 2 139 7.9E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS39880 afb739b3b86e48f29895af965abaf07c 156 SUPERFAMILY SSF46785 5 136 4.23E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS39880 afb739b3b86e48f29895af965abaf07c 156 SMART SM00347 26 126 5.5E-20 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS39880 afb739b3b86e48f29895af965abaf07c 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 116 136 5.5E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS39880 afb739b3b86e48f29895af965abaf07c 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 50 66 5.5E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS39880 afb739b3b86e48f29895af965abaf07c 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 86 102 5.5E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS39880 afb739b3b86e48f29895af965abaf07c 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 67 82 5.5E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS32860 e96651389b89fd27bb409094711f68e8 188 SUPERFAMILY SSF54197 22 179 2.78E-41 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 SMALA_RS32860 e96651389b89fd27bb409094711f68e8 188 Gene3D G3DSA:3.30.428.10 8 187 2.7E-44 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 SMALA_RS32860 e96651389b89fd27bb409094711f68e8 188 Pfam PF01230 HIT domain 60 151 3.5E-12 T 29-03-2018 IPR001310 Histidine triad (HIT) protein SMALA_RS38600 9f2e27c5780f1795fde4e6b8f1d7968d 257 Pfam PF00378 Enoyl-CoA hydratase/isomerase 13 212 9.2E-32 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 SMALA_RS38600 9f2e27c5780f1795fde4e6b8f1d7968d 257 Gene3D G3DSA:3.90.226.10 3 245 9.6E-49 T 29-03-2018 SMALA_RS38600 9f2e27c5780f1795fde4e6b8f1d7968d 257 SUPERFAMILY SSF52096 8 215 1.3E-49 T 29-03-2018 IPR029045 ClpP/crotonase-like domain SMALA_RS09375 aba3dc017bd23f32bc09e9a8e6edb1ee 192 Pfam PF00857 Isochorismatase family 12 183 1.9E-35 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SMALA_RS09375 aba3dc017bd23f32bc09e9a8e6edb1ee 192 SUPERFAMILY SSF52499 8 188 8.9E-48 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SMALA_RS09375 aba3dc017bd23f32bc09e9a8e6edb1ee 192 Gene3D G3DSA:3.40.50.850 1 191 8.1E-43 T 29-03-2018 SMALA_RS14985 4cb3a2433885190fe4af38d3ab108914 120 Pfam PF12277 Protein of unknown function (DUF3618) 4 49 2.9E-15 T 29-03-2018 IPR022062 Protein of unknown function DUF3618 SMALA_RS03295 3c8cc296f9b21b4a89c654bd7eca448c 266 Pfam PF02517 CAAX protease self-immunity 159 247 7.9E-14 T 29-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 SMALA_RS16740 b91ee1087dbbde2d8e986c8951db7a69 535 SUPERFAMILY SSF51905 116 195 7.99E-52 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS16740 b91ee1087dbbde2d8e986c8951db7a69 535 SUPERFAMILY SSF51905 283 372 7.99E-52 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS16740 b91ee1087dbbde2d8e986c8951db7a69 535 SUPERFAMILY SSF51905 1 68 7.99E-52 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS16740 b91ee1087dbbde2d8e986c8951db7a69 535 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 296 311 2.8E-42 T 29-03-2018 SMALA_RS16740 b91ee1087dbbde2d8e986c8951db7a69 535 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 174 189 2.8E-42 T 29-03-2018 SMALA_RS16740 b91ee1087dbbde2d8e986c8951db7a69 535 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 347 363 2.8E-42 T 29-03-2018 SMALA_RS16740 b91ee1087dbbde2d8e986c8951db7a69 535 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 311 327 2.8E-42 T 29-03-2018 SMALA_RS16740 b91ee1087dbbde2d8e986c8951db7a69 535 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 329 347 2.8E-42 T 29-03-2018 SMALA_RS16740 b91ee1087dbbde2d8e986c8951db7a69 535 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 2.8E-42 T 29-03-2018 SMALA_RS16740 b91ee1087dbbde2d8e986c8951db7a69 535 Pfam PF01494 FAD binding domain 1 361 1.5E-69 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 SMALA_RS16740 b91ee1087dbbde2d8e986c8951db7a69 535 Gene3D G3DSA:3.50.50.60 1 406 6.1E-58 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS32535 95e1c71c8c0a1ca9be12c7d58995ad4b 173 Gene3D G3DSA:1.10.10.10 69 162 1.9E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS32535 95e1c71c8c0a1ca9be12c7d58995ad4b 173 Gene3D G3DSA:1.10.1740.10 2 68 6.0E-7 T 29-03-2018 SMALA_RS32535 95e1c71c8c0a1ca9be12c7d58995ad4b 173 SUPERFAMILY SSF88659 89 160 3.18E-7 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS23525 6e5ddcf54629aae2e5bb3b5dc4e3a068 189 SUPERFAMILY SSF69118 8 187 1.44E-23 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 SMALA_RS23525 6e5ddcf54629aae2e5bb3b5dc4e3a068 189 Gene3D G3DSA:1.20.1290.10 34 189 5.4E-22 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 SMALA_RS03795 2d19d7441e0b58217e18a49c809b30dc 397 PRINTS PR00359 B-class P450 signature 282 309 3.1E-58 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS03795 2d19d7441e0b58217e18a49c809b30dc 397 PRINTS PR00359 B-class P450 signature 129 145 3.1E-58 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS03795 2d19d7441e0b58217e18a49c809b30dc 397 PRINTS PR00359 B-class P450 signature 146 161 3.1E-58 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS03795 2d19d7441e0b58217e18a49c809b30dc 397 PRINTS PR00359 B-class P450 signature 264 275 3.1E-58 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS03795 2d19d7441e0b58217e18a49c809b30dc 397 PRINTS PR00359 B-class P450 signature 331 340 3.1E-58 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS03795 2d19d7441e0b58217e18a49c809b30dc 397 PRINTS PR00359 B-class P450 signature 83 94 3.1E-58 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS03795 2d19d7441e0b58217e18a49c809b30dc 397 PRINTS PR00359 B-class P450 signature 182 204 3.1E-58 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS03795 2d19d7441e0b58217e18a49c809b30dc 397 PRINTS PR00359 B-class P450 signature 340 351 3.1E-58 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS03795 2d19d7441e0b58217e18a49c809b30dc 397 PRINTS PR00359 B-class P450 signature 310 325 3.1E-58 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS03795 2d19d7441e0b58217e18a49c809b30dc 397 SUPERFAMILY SSF48264 9 391 1.14E-100 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS03795 2d19d7441e0b58217e18a49c809b30dc 397 Pfam PF00067 Cytochrome P450 175 361 1.2E-21 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS03795 2d19d7441e0b58217e18a49c809b30dc 397 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 333 342 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMALA_RS03795 2d19d7441e0b58217e18a49c809b30dc 397 Gene3D G3DSA:1.10.630.10 3 393 1.2E-79 T 29-03-2018 SMALA_RS32235 728934cc35596e6d9241e79d2fb9a52b 498 PIRSF PIRSF006060 31 495 4.1E-64 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMALA_RS32235 728934cc35596e6d9241e79d2fb9a52b 498 Pfam PF13520 Amino acid permease 55 455 9.5E-41 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMALA_RS32235 728934cc35596e6d9241e79d2fb9a52b 498 TIGRFAM TIGR00908 2A0305: ethanolamine permease 37 484 9.4E-144 T 29-03-2018 IPR004757 Ethanolamine permease SMALA_RS23285 c1d4cd4707113cd799b2ce4b34f70ffc 428 Gene3D G3DSA:3.40.190.10 41 345 6.4E-16 T 29-03-2018 SMALA_RS23285 c1d4cd4707113cd799b2ce4b34f70ffc 428 SUPERFAMILY SSF53850 38 342 6.09E-30 T 29-03-2018 SMALA_RS23285 c1d4cd4707113cd799b2ce4b34f70ffc 428 Pfam PF01547 Bacterial extracellular solute-binding protein 47 324 1.1E-8 T 29-03-2018 IPR006059 Solute-binding family 1 GO:0006810 SMALA_RS31700 3174c384270dc4b4a29bb2e3c793f12c 254 SUPERFAMILY SSF51735 6 247 3.14E-75 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS31700 3174c384270dc4b4a29bb2e3c793f12c 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 9.3E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS31700 3174c384270dc4b4a29bb2e3c793f12c 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 9.3E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS31700 3174c384270dc4b4a29bb2e3c793f12c 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 9.3E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS31700 3174c384270dc4b4a29bb2e3c793f12c 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 1.2E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS31700 3174c384270dc4b4a29bb2e3c793f12c 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 1.2E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS31700 3174c384270dc4b4a29bb2e3c793f12c 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.2E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS31700 3174c384270dc4b4a29bb2e3c793f12c 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 1.2E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS31700 3174c384270dc4b4a29bb2e3c793f12c 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 1.2E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS31700 3174c384270dc4b4a29bb2e3c793f12c 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 1.2E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS31700 3174c384270dc4b4a29bb2e3c793f12c 254 Gene3D G3DSA:3.40.50.720 43 253 4.9E-58 T 29-03-2018 SMALA_RS31700 3174c384270dc4b4a29bb2e3c793f12c 254 Gene3D G3DSA:3.40.50.720 1 42 3.3E-11 T 29-03-2018 SMALA_RS31700 3174c384270dc4b4a29bb2e3c793f12c 254 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMALA_RS31700 3174c384270dc4b4a29bb2e3c793f12c 254 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 189 0.0026 T 29-03-2018 SMALA_RS31700 3174c384270dc4b4a29bb2e3c793f12c 254 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 246 4.6E-57 T 29-03-2018 SMALA_RS29145 5a2093dd391406f1c71ec0095896c077 257 SUPERFAMILY SSF54593 140 252 4.03E-18 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS29145 5a2093dd391406f1c71ec0095896c077 257 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 145 249 5.5E-7 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMALA_RS29145 5a2093dd391406f1c71ec0095896c077 257 SUPERFAMILY SSF54593 13 125 3.89E-17 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS29145 5a2093dd391406f1c71ec0095896c077 257 Gene3D G3DSA:3.10.180.10 131 257 9.8E-20 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS29145 5a2093dd391406f1c71ec0095896c077 257 Gene3D G3DSA:3.10.180.10 1 130 7.6E-16 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS28000 d63a78cae0e86722ebe14004b12ce119 169 Gene3D G3DSA:3.40.50.620 3 167 8.0E-34 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS28000 d63a78cae0e86722ebe14004b12ce119 169 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 13 165 4.5E-59 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 SMALA_RS28000 d63a78cae0e86722ebe14004b12ce119 169 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 121 143 3.4E-48 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 SMALA_RS28000 d63a78cae0e86722ebe14004b12ce119 169 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 30 51 3.4E-48 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 SMALA_RS28000 d63a78cae0e86722ebe14004b12ce119 169 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 59 83 3.4E-48 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 SMALA_RS28000 d63a78cae0e86722ebe14004b12ce119 169 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 95 111 3.4E-48 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 SMALA_RS28000 d63a78cae0e86722ebe14004b12ce119 169 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 12 30 3.4E-48 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 SMALA_RS28000 d63a78cae0e86722ebe14004b12ce119 169 ProDom PD016147 LIGASE LYASE CITRATE PRO-3S-LYASE SYNTHETASE TRANSFERASE CYTIDYLTRANSFERASE-RELATED:CITRATE ACETATE:SH-CITRATE CITC PLASMID 21 76 9.0E-4 T 29-03-2018 SMALA_RS28000 d63a78cae0e86722ebe14004b12ce119 169 Pfam PF01467 Cytidylyltransferase-like 16 142 5.5E-18 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 SMALA_RS28000 d63a78cae0e86722ebe14004b12ce119 169 SUPERFAMILY SSF52374 12 165 1.38E-44 T 29-03-2018 SMALA_RS28000 d63a78cae0e86722ebe14004b12ce119 169 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 13 68 3.0E-15 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 SMALA_RS28000 d63a78cae0e86722ebe14004b12ce119 169 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 12 167 34.516 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 SMALA_RS06830 f1d01b2c485727dba076bcc17423e707 565 Gene3D G3DSA:3.40.50.980 223 381 5.4E-34 T 29-03-2018 SMALA_RS06830 f1d01b2c485727dba076bcc17423e707 565 Gene3D G3DSA:3.40.50.980 39 222 2.3E-35 T 29-03-2018 SMALA_RS06830 f1d01b2c485727dba076bcc17423e707 565 Pfam PF00501 AMP-binding enzyme 48 462 7.7E-69 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS06830 f1d01b2c485727dba076bcc17423e707 565 Gene3D G3DSA:3.30.300.30 462 563 3.2E-16 T 29-03-2018 SMALA_RS06830 f1d01b2c485727dba076bcc17423e707 565 Pfam PF13193 AMP-binding enzyme C-terminal domain 473 547 4.4E-9 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS06830 f1d01b2c485727dba076bcc17423e707 565 ProSitePatterns PS00455 Putative AMP-binding domain signature. 217 228 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS06830 f1d01b2c485727dba076bcc17423e707 565 Gene3D G3DSA:2.30.38.10 382 458 2.4E-6 T 29-03-2018 SMALA_RS06830 f1d01b2c485727dba076bcc17423e707 565 SUPERFAMILY SSF56801 43 559 6.93E-102 T 29-03-2018 SMALA_RS29380 1a72178ef94b60535b8673e5f315734e 254 SUPERFAMILY SSF46894 193 252 1.29E-8 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS29380 1a72178ef94b60535b8673e5f315734e 254 Gene3D G3DSA:1.10.10.10 106 251 4.6E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS29380 1a72178ef94b60535b8673e5f315734e 254 SMART SM00421 197 246 0.0052 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS14760 3dbb7f036451061fa4cd62d74204a5cf 521 Gene3D G3DSA:1.20.1250.20 21 216 5.2E-33 T 29-03-2018 SMALA_RS14760 3dbb7f036451061fa4cd62d74204a5cf 521 SUPERFAMILY SSF103473 486 514 2.22E-70 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS14760 3dbb7f036451061fa4cd62d74204a5cf 521 SUPERFAMILY SSF103473 265 436 2.22E-70 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS14760 3dbb7f036451061fa4cd62d74204a5cf 521 SUPERFAMILY SSF103473 14 216 2.22E-70 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS14760 3dbb7f036451061fa4cd62d74204a5cf 521 Gene3D G3DSA:1.20.1250.20 276 520 3.4E-30 T 29-03-2018 SMALA_RS14760 3dbb7f036451061fa4cd62d74204a5cf 521 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 28 507 8.0E-76 T 29-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 SMALA_RS14760 3dbb7f036451061fa4cd62d74204a5cf 521 Pfam PF07690 Major Facilitator Superfamily 32 426 1.8E-53 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS04650 00c7f1b592e13c21460554d39de8fbb8 437 Gene3D G3DSA:3.40.640.10 51 310 2.9E-64 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS04650 00c7f1b592e13c21460554d39de8fbb8 437 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 240 277 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMALA_RS04650 00c7f1b592e13c21460554d39de8fbb8 437 SUPERFAMILY SSF53383 22 432 6.53E-108 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS04650 00c7f1b592e13c21460554d39de8fbb8 437 Pfam PF00202 Aminotransferase class-III 27 430 7.4E-85 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMALA_RS04650 00c7f1b592e13c21460554d39de8fbb8 437 Gene3D G3DSA:3.90.1150.10 311 434 3.9E-29 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS42000 103083fe01922fbccce3acd34ef4623b 370 SUPERFAMILY SSF55298 258 369 5.55E-12 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SMALA_RS42000 103083fe01922fbccce3acd34ef4623b 370 TIGRFAM TIGR04444 chori_FkbO_Hyg5: chorismatase, FkbO/Hyg5 family 59 369 1.0E-154 T 29-03-2018 IPR031038 Chorismatase, FkbO/Hyg5 family GO:0055114 SMALA_RS42000 103083fe01922fbccce3acd34ef4623b 370 Gene3D G3DSA:3.30.1330.40 230 370 4.8E-20 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SMALA_RS38900 b707fedb55bd05355daeb99f5d01eb14 175 Pfam PF11706 CGNR zinc finger 120 163 1.6E-17 T 29-03-2018 IPR021005 Zinc finger, CGNR SMALA_RS38900 b707fedb55bd05355daeb99f5d01eb14 175 Pfam PF07336 Putative stress-induced transcription regulator 7 104 6.1E-7 T 29-03-2018 IPR010852 Putative stress-induced transcription regulator SMALA_RS38900 b707fedb55bd05355daeb99f5d01eb14 175 SUPERFAMILY SSF160904 4 162 6.28E-35 T 29-03-2018 SMALA_RS38900 b707fedb55bd05355daeb99f5d01eb14 175 Gene3D G3DSA:1.10.3300.10 1 165 2.2E-34 T 29-03-2018 IPR023286 ABATE domain SMALA_RS03265 b6a17683d2f30f0bceee3d8fed40c5e3 233 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 35 183 1.1E-49 T 29-03-2018 IPR024747 Pyridoxamine 5'-phosphate oxidase-related SMALA_RS03265 b6a17683d2f30f0bceee3d8fed40c5e3 233 Gene3D G3DSA:2.30.110.10 3 203 1.3E-51 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS03265 b6a17683d2f30f0bceee3d8fed40c5e3 233 SUPERFAMILY SSF50475 16 205 8.48E-61 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS41440 0f2fc72732d12a63df56a855c80fe8c0 200 Gene3D G3DSA:3.40.50.300 26 172 1.2E-16 T 29-03-2018 SMALA_RS41440 0f2fc72732d12a63df56a855c80fe8c0 200 SUPERFAMILY SSF52540 28 167 1.09E-16 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS41440 0f2fc72732d12a63df56a855c80fe8c0 200 Pfam PF13671 AAA domain 28 166 9.3E-22 T 29-03-2018 SMALA_RS16455 1a7629c9b778d615dda1e05566b3a30f 204 Gene3D G3DSA:3.40.190.10 1 185 5.4E-4 T 29-03-2018 SMALA_RS33445 bd1191dfa82dc56c8371b7c6e1f7e608 318 SUPERFAMILY SSF51197 21 308 6.41E-64 T 29-03-2018 SMALA_RS33445 bd1191dfa82dc56c8371b7c6e1f7e608 318 Gene3D G3DSA:3.60.130.10 2 309 3.8E-58 T 29-03-2018 SMALA_RS33445 bd1191dfa82dc56c8371b7c6e1f7e608 318 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 24 306 2.4E-42 T 29-03-2018 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 SMALA_RS29885 826ba873d2787ba24b5b5c515a359193 496 Gene3D G3DSA:3.90.660.20 58 121 5.3E-4 T 29-03-2018 SMALA_RS29885 826ba873d2787ba24b5b5c515a359193 496 Gene3D G3DSA:1.10.3110.10 122 204 9.6E-22 T 29-03-2018 SMALA_RS29885 826ba873d2787ba24b5b5c515a359193 496 TIGRFAM TIGR00562 proto_IX_ox: protoporphyrinogen oxidase 13 479 3.2E-60 T 29-03-2018 IPR004572 Protoporphyrinogen oxidase GO:0004729|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.4|MetaCyc: PWY-7159|Reactome: R-HSA-189451 SMALA_RS29885 826ba873d2787ba24b5b5c515a359193 496 Pfam PF01593 Flavin containing amine oxidoreductase 22 479 6.5E-47 T 29-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 SMALA_RS29885 826ba873d2787ba24b5b5c515a359193 496 Gene3D G3DSA:3.50.50.60 3 57 6.7E-5 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS29885 826ba873d2787ba24b5b5c515a359193 496 SUPERFAMILY SSF51905 14 333 4.66E-57 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS29885 826ba873d2787ba24b5b5c515a359193 496 SUPERFAMILY SSF51905 447 479 4.66E-57 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS29885 826ba873d2787ba24b5b5c515a359193 496 SUPERFAMILY SSF54373 317 430 2.35E-24 T 29-03-2018 SMALA_RS29885 826ba873d2787ba24b5b5c515a359193 496 Gene3D G3DSA:3.90.660.20 238 430 7.9E-43 T 29-03-2018 SMALA_RS12670 b53b47f600dea43d18041c5c7666df2b 284 Pfam PF13560 Helix-turn-helix domain 5 84 4.9E-15 T 29-03-2018 SMALA_RS12670 b53b47f600dea43d18041c5c7666df2b 284 SMART SM00530 9 81 5.8E-4 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS12670 b53b47f600dea43d18041c5c7666df2b 284 Gene3D G3DSA:1.10.260.40 1 84 1.3E-11 T 29-03-2018 SMALA_RS28270 f22bea582b4b82ff1b32cdafb48f8010 365 SUPERFAMILY SSF102405 241 360 3.97E-28 T 29-03-2018 SMALA_RS28270 f22bea582b4b82ff1b32cdafb48f8010 365 SUPERFAMILY SSF102405 144 200 3.97E-28 T 29-03-2018 SMALA_RS28270 f22bea582b4b82ff1b32cdafb48f8010 365 Gene3D G3DSA:3.40.50.450 135 363 5.0E-51 T 29-03-2018 SMALA_RS28270 f22bea582b4b82ff1b32cdafb48f8010 365 Pfam PF03641 Possible lysine decarboxylase 241 360 1.6E-6 T 29-03-2018 IPR031100 LOG family SMALA_RS39435 9da01a74124e67cfb2b388bb77e795f3 107 SUPERFAMILY SSF54292 3 105 1.39E-29 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SMALA_RS39435 9da01a74124e67cfb2b388bb77e795f3 107 PRINTS PR00355 Adrenodoxin signature 59 73 2.5E-7 T 29-03-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 SMALA_RS39435 9da01a74124e67cfb2b388bb77e795f3 107 PRINTS PR00355 Adrenodoxin signature 40 50 2.5E-7 T 29-03-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 SMALA_RS39435 9da01a74124e67cfb2b388bb77e795f3 107 PRINTS PR00355 Adrenodoxin signature 83 91 2.5E-7 T 29-03-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 SMALA_RS39435 9da01a74124e67cfb2b388bb77e795f3 107 Gene3D G3DSA:3.10.20.30 2 106 4.8E-26 T 29-03-2018 IPR012675 Beta-grasp domain SMALA_RS39435 9da01a74124e67cfb2b388bb77e795f3 107 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 11 92 7.5E-11 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SMALA_RS38995 7ac02bba926dd227a824b8f3b3105001 326 SUPERFAMILY SSF51735 127 251 4.18E-28 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS38995 7ac02bba926dd227a824b8f3b3105001 326 SMART SM00829 14 320 1.7E-9 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS38995 7ac02bba926dd227a824b8f3b3105001 326 Gene3D G3DSA:3.90.180.10 1 154 1.8E-38 T 29-03-2018 SMALA_RS38995 7ac02bba926dd227a824b8f3b3105001 326 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 30 96 1.0E-8 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS38995 7ac02bba926dd227a824b8f3b3105001 326 SUPERFAMILY SSF50129 4 159 9.43E-34 T 29-03-2018 IPR011032 GroES-like SMALA_RS38995 7ac02bba926dd227a824b8f3b3105001 326 Gene3D G3DSA:3.40.50.720 155 270 3.0E-19 T 29-03-2018 SMALA_RS38995 7ac02bba926dd227a824b8f3b3105001 326 Pfam PF00107 Zinc-binding dehydrogenase 163 251 1.0E-13 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMALA_RS40830 0bd494089362fc2142dfd405eb9e21db 339 Gene3D G3DSA:1.10.3470.10 47 326 1.1E-27 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SMALA_RS40830 0bd494089362fc2142dfd405eb9e21db 339 Pfam PF02653 Branched-chain amino acid transport system / permease component 53 318 2.4E-47 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 SMALA_RS37730 01c3774780561150e02477b477ea6c08 223 SUPERFAMILY SSF54106 173 220 1.57E-6 T 29-03-2018 IPR018392 LysM domain SMALA_RS37730 01c3774780561150e02477b477ea6c08 223 Pfam PF01476 LysM domain 174 220 6.4E-10 T 29-03-2018 IPR018392 LysM domain SMALA_RS37730 01c3774780561150e02477b477ea6c08 223 Gene3D G3DSA:3.10.350.10 169 223 1.2E-13 T 29-03-2018 SMALA_RS37730 01c3774780561150e02477b477ea6c08 223 SMART SM00257 173 220 1.3E-7 T 29-03-2018 IPR018392 LysM domain SMALA_RS34995 c93c845ea004e0769da6240551120a67 191 SUPERFAMILY SSF48150 12 143 4.89E-12 T 29-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 SMALA_RS34995 c93c845ea004e0769da6240551120a67 191 Gene3D G3DSA:1.10.340.30 18 142 1.7E-12 T 29-03-2018 SMALA_RS34995 c93c845ea004e0769da6240551120a67 191 TIGRFAM TIGR03252 TIGR03252: uncharacterized HhH-GPD family protein 5 190 1.4E-92 T 29-03-2018 IPR017658 Conserved hypothetical protein CHP03252, HhH-GPD SMALA_RS34995 c93c845ea004e0769da6240551120a67 191 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 26 189 2.3E-12 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 SMALA_RS21965 ebfe674bb630321d92236f1509e6ce3e 607 Pfam PF05140 ResB-like family 65 544 1.6E-130 T 29-03-2018 IPR007816 ResB-like domain SMALA_RS01390 30a80e202ff6edf604fe36169169b4a4 197 Gene3D G3DSA:1.10.10.60 5 77 7.9E-21 T 29-03-2018 SMALA_RS01390 30a80e202ff6edf604fe36169169b4a4 197 SUPERFAMILY SSF48498 82 189 7.71E-17 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS01390 30a80e202ff6edf604fe36169169b4a4 197 ProSitePatterns PS01081 TetR-type HTH domain signature. 32 62 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site SMALA_RS01390 30a80e202ff6edf604fe36169169b4a4 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 66 7.9E-19 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS01390 30a80e202ff6edf604fe36169169b4a4 197 Gene3D G3DSA:1.10.357.10 78 191 5.9E-23 T 29-03-2018 SMALA_RS01390 30a80e202ff6edf604fe36169169b4a4 197 SUPERFAMILY SSF46689 8 75 4.1E-19 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS01390 30a80e202ff6edf604fe36169169b4a4 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 2.6E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS01390 30a80e202ff6edf604fe36169169b4a4 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 2.6E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS05575 15fb1b6bd2182587daff2e58fb0bf015 384 Gene3D G3DSA:1.20.1250.20 1 186 1.4E-23 T 29-03-2018 SMALA_RS05575 15fb1b6bd2182587daff2e58fb0bf015 384 Pfam PF07690 Major Facilitator Superfamily 6 256 4.6E-24 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS05575 15fb1b6bd2182587daff2e58fb0bf015 384 PRINTS PR01035 Tetracycline resistance protein signature 36 55 5.2E-7 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 SMALA_RS05575 15fb1b6bd2182587daff2e58fb0bf015 384 PRINTS PR01035 Tetracycline resistance protein signature 323 346 5.2E-7 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 SMALA_RS05575 15fb1b6bd2182587daff2e58fb0bf015 384 PRINTS PR01035 Tetracycline resistance protein signature 125 147 5.2E-7 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 SMALA_RS05575 15fb1b6bd2182587daff2e58fb0bf015 384 Gene3D G3DSA:1.20.1250.20 187 378 1.5E-16 T 29-03-2018 SMALA_RS05575 15fb1b6bd2182587daff2e58fb0bf015 384 SUPERFAMILY SSF103473 4 374 2.35E-46 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS01730 75f04eba97adfbbb4ee1b194bfb44c9d 152 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 131 1.4E-31 T 29-03-2018 IPR000944 Transcription regulator Rrf2-type SMALA_RS01730 75f04eba97adfbbb4ee1b194bfb44c9d 152 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 49 67 - T 29-03-2018 IPR030489 Transcription regulator Rrf2-type, conserved site SMALA_RS01730 75f04eba97adfbbb4ee1b194bfb44c9d 152 Pfam PF02082 Transcriptional regulator 1 83 5.8E-25 T 29-03-2018 IPR000944 Transcription regulator Rrf2-type SMALA_RS01730 75f04eba97adfbbb4ee1b194bfb44c9d 152 Gene3D G3DSA:1.10.10.10 1 136 1.7E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS01730 75f04eba97adfbbb4ee1b194bfb44c9d 152 SUPERFAMILY SSF46785 2 132 3.02E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS10870 f2ffc095392bb5807d1871eb17b37e41 337 Gene3D G3DSA:1.20.58.370 33 73 1.2E-5 T 29-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain SMALA_RS10870 f2ffc095392bb5807d1871eb17b37e41 337 Gene3D G3DSA:1.10.3720.10 104 334 5.7E-50 T 29-03-2018 SMALA_RS10870 f2ffc095392bb5807d1871eb17b37e41 337 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 129 326 6.7E-21 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS10870 f2ffc095392bb5807d1871eb17b37e41 337 SUPERFAMILY SSF161098 96 324 1.31E-65 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS18270 99bf80f901da760b53e1706e2217c825 392 Gene3D G3DSA:3.40.50.200 20 327 7.3E-68 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMALA_RS18270 99bf80f901da760b53e1706e2217c825 392 Pfam PF00082 Subtilase family 61 313 6.0E-31 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMALA_RS18270 99bf80f901da760b53e1706e2217c825 392 SUPERFAMILY SSF52743 44 322 3.27E-66 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMALA_RS18270 99bf80f901da760b53e1706e2217c825 392 PRINTS PR00723 Subtilisin serine protease family (S8) signature 104 117 1.5E-12 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related SMALA_RS18270 99bf80f901da760b53e1706e2217c825 392 PRINTS PR00723 Subtilisin serine protease family (S8) signature 262 278 1.5E-12 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related SMALA_RS18270 99bf80f901da760b53e1706e2217c825 392 PRINTS PR00723 Subtilisin serine protease family (S8) signature 61 80 1.5E-12 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related SMALA_RS08905 599e6a8d225b8cc456adb0671c5c3da9 172 SMART SM00855 8 119 0.0029 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SMALA_RS08905 599e6a8d225b8cc456adb0671c5c3da9 172 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 9 94 2.4E-8 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SMALA_RS08905 599e6a8d225b8cc456adb0671c5c3da9 172 Gene3D G3DSA:3.40.50.1240 3 172 1.9E-28 T 29-03-2018 IPR029033 Histidine phosphatase superfamily SMALA_RS08905 599e6a8d225b8cc456adb0671c5c3da9 172 SUPERFAMILY SSF53254 6 159 4.5E-22 T 29-03-2018 IPR029033 Histidine phosphatase superfamily SMALA_RS13185 feb6ef02e86e4bdf5c4dc7cb34d5456a 117 Pfam PF14017 Protein of unknown function (DUF4233) 2 105 2.3E-31 T 29-03-2018 IPR025327 Protein of unknown function DUF4233 SMALA_RS36345 c39a755a91e9ec186007d027df0a0ad5 510 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 376 387 - T 29-03-2018 IPR033116 Serine proteases, trypsin family, serine active site SMALA_RS36345 c39a755a91e9ec186007d027df0a0ad5 510 Gene3D G3DSA:2.40.10.10 237 321 5.6E-23 T 29-03-2018 SMALA_RS36345 c39a755a91e9ec186007d027df0a0ad5 510 Gene3D G3DSA:3.30.300.50 97 167 4.0E-21 T 29-03-2018 IPR035070 Streptogrisin prodomain SMALA_RS36345 c39a755a91e9ec186007d027df0a0ad5 510 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 367 390 1.7E-42 T 29-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMALA_RS36345 c39a755a91e9ec186007d027df0a0ad5 510 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 391 405 1.7E-42 T 29-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMALA_RS36345 c39a755a91e9ec186007d027df0a0ad5 510 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 263 277 1.7E-42 T 29-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMALA_RS36345 c39a755a91e9ec186007d027df0a0ad5 510 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 326 346 1.7E-42 T 29-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMALA_RS36345 c39a755a91e9ec186007d027df0a0ad5 510 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 347 364 1.7E-42 T 29-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMALA_RS36345 c39a755a91e9ec186007d027df0a0ad5 510 Gene3D G3DSA:2.40.10.10 322 413 1.1E-21 T 29-03-2018 SMALA_RS36345 c39a755a91e9ec186007d027df0a0ad5 510 Pfam PF02983 Alpha-lytic protease prodomain 101 154 8.0E-16 T 29-03-2018 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 SMALA_RS36345 c39a755a91e9ec186007d027df0a0ad5 510 SUPERFAMILY SSF50494 243 420 1.07E-35 T 29-03-2018 IPR009003 Peptidase S1, PA clan SMALA_RS36345 c39a755a91e9ec186007d027df0a0ad5 510 Gene3D G3DSA:3.30.300.50 18 96 8.2E-15 T 29-03-2018 IPR035070 Streptogrisin prodomain SMALA_RS36345 c39a755a91e9ec186007d027df0a0ad5 510 PIRSF PIRSF001134 229 428 1.4E-78 T 29-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMALA_RS36345 c39a755a91e9ec186007d027df0a0ad5 510 PIRSF PIRSF001134 1 186 4.5E-32 T 29-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMALA_RS22220 b5c36eced9a7f09e916f3a4807de1806 332 Gene3D G3DSA:3.40.630.10 55 332 2.6E-69 T 29-03-2018 SMALA_RS22220 b5c36eced9a7f09e916f3a4807de1806 332 Pfam PF04389 Peptidase family M28 120 325 2.4E-48 T 29-03-2018 IPR007484 Peptidase M28 SMALA_RS22220 b5c36eced9a7f09e916f3a4807de1806 332 SUPERFAMILY SSF53187 64 329 1.2E-72 T 29-03-2018 SMALA_RS27080 8f9ceecae4b7c1a8f0248d5bd3c76c1e 226 Gene3D G3DSA:3.60.160.10 17 218 4.0E-30 T 29-03-2018 IPR002838 Mitochondrial biogenesis protein AIM24 SMALA_RS27080 8f9ceecae4b7c1a8f0248d5bd3c76c1e 226 SUPERFAMILY SSF51219 21 211 8.11E-28 T 29-03-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain SMALA_RS27080 8f9ceecae4b7c1a8f0248d5bd3c76c1e 226 Pfam PF01987 Mitochondrial biogenesis AIM24 25 209 1.1E-9 T 29-03-2018 IPR002838 Mitochondrial biogenesis protein AIM24 SMALA_RS41370 ba4cbbea856bec6b08e28dcae271cb23 404 Gene3D G3DSA:3.40.50.1110 178 399 2.4E-21 T 29-03-2018 SMALA_RS41370 ba4cbbea856bec6b08e28dcae271cb23 404 SUPERFAMILY SSF52266 187 402 8.83E-33 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain SMALA_RS41370 ba4cbbea856bec6b08e28dcae271cb23 404 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 193 393 2.8E-16 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain SMALA_RS42100 e2ee60fdeaffa43151b4ff7e20b07d13 529 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 12 23 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMALA_RS42100 e2ee60fdeaffa43151b4ff7e20b07d13 529 SUPERFAMILY SSF47323 388 504 1.31E-6 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMALA_RS42100 e2ee60fdeaffa43151b4ff7e20b07d13 529 Gene3D G3DSA:3.40.50.620 255 351 1.8E-13 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS42100 e2ee60fdeaffa43151b4ff7e20b07d13 529 Gene3D G3DSA:3.40.50.620 2 254 8.1E-36 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS42100 e2ee60fdeaffa43151b4ff7e20b07d13 529 PRINTS PR01041 Methionyl-tRNA synthetase signature 89 100 3.5E-8 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 SMALA_RS42100 e2ee60fdeaffa43151b4ff7e20b07d13 529 PRINTS PR01041 Methionyl-tRNA synthetase signature 7 20 3.5E-8 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 SMALA_RS42100 e2ee60fdeaffa43151b4ff7e20b07d13 529 PRINTS PR01041 Methionyl-tRNA synthetase signature 40 54 3.5E-8 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 SMALA_RS42100 e2ee60fdeaffa43151b4ff7e20b07d13 529 PRINTS PR01041 Methionyl-tRNA synthetase signature 251 262 3.5E-8 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 SMALA_RS42100 e2ee60fdeaffa43151b4ff7e20b07d13 529 PRINTS PR01041 Methionyl-tRNA synthetase signature 280 295 3.5E-8 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 SMALA_RS42100 e2ee60fdeaffa43151b4ff7e20b07d13 529 SUPERFAMILY SSF52374 4 141 1.15E-66 T 29-03-2018 SMALA_RS42100 e2ee60fdeaffa43151b4ff7e20b07d13 529 SUPERFAMILY SSF52374 175 370 1.15E-66 T 29-03-2018 SMALA_RS42100 e2ee60fdeaffa43151b4ff7e20b07d13 529 Gene3D G3DSA:1.10.730.10 352 508 7.2E-10 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMALA_RS42100 e2ee60fdeaffa43151b4ff7e20b07d13 529 Pfam PF09334 tRNA synthetases class I (M) 6 369 4.6E-68 T 29-03-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMALA_RS08445 4db9169b85a83efaa48222f50dc07880 150 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 93 138 1.1E-7 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMALA_RS08445 4db9169b85a83efaa48222f50dc07880 150 Gene3D G3DSA:3.10.180.10 21 149 2.3E-22 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS08445 4db9169b85a83efaa48222f50dc07880 150 SUPERFAMILY SSF54593 23 141 5.64E-21 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS38275 12946c85e7edb1a6bb807d20c37f5096 211 SMART SM00448 1 117 3.1E-6 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS38275 12946c85e7edb1a6bb807d20c37f5096 211 SMART SM00421 145 202 2.3E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS38275 12946c85e7edb1a6bb807d20c37f5096 211 SUPERFAMILY SSF52172 2 172 5.54E-18 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS38275 12946c85e7edb1a6bb807d20c37f5096 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 148 162 3.1E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS38275 12946c85e7edb1a6bb807d20c37f5096 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 162 178 3.1E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS38275 12946c85e7edb1a6bb807d20c37f5096 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 178 190 3.1E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS38275 12946c85e7edb1a6bb807d20c37f5096 211 Gene3D G3DSA:3.40.50.2300 1 128 3.6E-25 T 29-03-2018 SMALA_RS38275 12946c85e7edb1a6bb807d20c37f5096 211 Pfam PF00072 Response regulator receiver domain 1 105 1.3E-17 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS38275 12946c85e7edb1a6bb807d20c37f5096 211 Pfam PF00196 Bacterial regulatory proteins, luxR family 147 194 2.4E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS38275 12946c85e7edb1a6bb807d20c37f5096 211 Gene3D G3DSA:1.10.10.10 129 211 3.6E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS08435 99b79f936adf912abb1213efc72401a0 193 SUPERFAMILY SSF52980 24 166 7.51E-19 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 SMALA_RS08435 99b79f936adf912abb1213efc72401a0 193 Gene3D G3DSA:3.90.1570.10 2 193 3.8E-32 T 29-03-2018 SMALA_RS08435 99b79f936adf912abb1213efc72401a0 193 Pfam PF05685 Putative restriction endonuclease 15 184 5.0E-28 T 29-03-2018 IPR008538 Domain of unknown function DUF820 SMALA_RS01370 0fd683fadc8b4efc86db7c1f01fb6d7c 67 SMART SM00923 2 48 2.2E-19 T 29-03-2018 IPR005153 MbtH-like protein SMALA_RS01370 0fd683fadc8b4efc86db7c1f01fb6d7c 67 Pfam PF03621 MbtH-like protein 2 48 1.9E-21 T 29-03-2018 IPR005153 MbtH-like protein SMALA_RS01370 0fd683fadc8b4efc86db7c1f01fb6d7c 67 Gene3D G3DSA:3.90.820.10 1 63 1.1E-31 T 29-03-2018 SMALA_RS01370 0fd683fadc8b4efc86db7c1f01fb6d7c 67 SUPERFAMILY SSF160582 2 64 6.28E-28 T 29-03-2018 SMALA_RS04655 596a3d7ecb25f064e0cd00bb9c608ef2 310 Gene3D G3DSA:3.40.190.10 181 268 2.5E-22 T 29-03-2018 SMALA_RS04655 596a3d7ecb25f064e0cd00bb9c608ef2 310 SUPERFAMILY SSF46785 1 109 6.71E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS04655 596a3d7ecb25f064e0cd00bb9c608ef2 310 Gene3D G3DSA:3.40.190.10 93 180 2.8E-20 T 29-03-2018 SMALA_RS04655 596a3d7ecb25f064e0cd00bb9c608ef2 310 Gene3D G3DSA:1.10.10.10 2 92 1.5E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS04655 596a3d7ecb25f064e0cd00bb9c608ef2 310 Pfam PF03466 LysR substrate binding domain 88 293 1.2E-39 T 29-03-2018 IPR005119 LysR, substrate-binding SMALA_RS04655 596a3d7ecb25f064e0cd00bb9c608ef2 310 SUPERFAMILY SSF53850 89 293 2.9E-35 T 29-03-2018 SMALA_RS04655 596a3d7ecb25f064e0cd00bb9c608ef2 310 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 62 1.4E-13 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS17610 540d9489a408460c599439bbe68a0893 212 Gene3D G3DSA:3.60.15.10 22 210 6.0E-36 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS17610 540d9489a408460c599439bbe68a0893 212 SMART SM00849 27 191 1.9E-35 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS17610 540d9489a408460c599439bbe68a0893 212 SUPERFAMILY SSF56281 13 204 7.31E-45 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS17610 540d9489a408460c599439bbe68a0893 212 Pfam PF00753 Metallo-beta-lactamase superfamily 27 191 5.2E-23 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS15835 48cb1642d44de81e923ede6dc267f848 434 Pfam PF10432 Bacterial phospho-glucose isomerase C-terminal SIS domain 283 429 1.1E-16 T 29-03-2018 IPR019490 Bifunctional glucose-6-phosphate/mannose-6-phosphate isomerase, C-terminal GO:0004347|GO:0004476|GO:0005975 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00051+5.3.1.8|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.8+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 SMALA_RS15835 48cb1642d44de81e923ede6dc267f848 434 Gene3D G3DSA:3.40.50.10490 2 188 5.1E-6 T 29-03-2018 SMALA_RS15835 48cb1642d44de81e923ede6dc267f848 434 SUPERFAMILY SSF53697 225 429 1.56E-27 T 29-03-2018 SMALA_RS15835 48cb1642d44de81e923ede6dc267f848 434 Gene3D G3DSA:3.40.50.10490 275 430 4.4E-34 T 29-03-2018 SMALA_RS15835 48cb1642d44de81e923ede6dc267f848 434 SUPERFAMILY SSF53697 70 178 1.65E-11 T 29-03-2018 SMALA_RS12560 25de14dc6e0589de19f94806f620dda3 401 Pfam PF01547 Bacterial extracellular solute-binding protein 36 302 1.0E-29 T 29-03-2018 IPR006059 Solute-binding family 1 GO:0006810 SMALA_RS12560 25de14dc6e0589de19f94806f620dda3 401 Gene3D G3DSA:3.40.190.10 145 333 3.3E-33 T 29-03-2018 SMALA_RS12560 25de14dc6e0589de19f94806f620dda3 401 Gene3D G3DSA:3.40.190.10 20 144 4.7E-16 T 29-03-2018 SMALA_RS12560 25de14dc6e0589de19f94806f620dda3 401 SUPERFAMILY SSF53850 3 394 1.52E-61 T 29-03-2018 SMALA_RS26370 fcab4bd8f9ac004b7cea4081e494a9a5 192 Gene3D G3DSA:3.40.80.10 14 191 1.4E-29 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 SMALA_RS26370 fcab4bd8f9ac004b7cea4081e494a9a5 192 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 35 175 2.3E-19 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 SMALA_RS26370 fcab4bd8f9ac004b7cea4081e494a9a5 192 SMART SM00644 23 176 8.9E-24 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 SMALA_RS26370 fcab4bd8f9ac004b7cea4081e494a9a5 192 SUPERFAMILY SSF55846 14 188 7.2E-25 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 SMALA_RS41835 47a2c4ffd6f6bdff97fbde804cb5bddf 574 Gene3D G3DSA:3.40.50.980 39 205 6.0E-31 T 29-03-2018 SMALA_RS41835 47a2c4ffd6f6bdff97fbde804cb5bddf 574 Pfam PF13193 AMP-binding enzyme C-terminal domain 459 536 1.6E-17 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS41835 47a2c4ffd6f6bdff97fbde804cb5bddf 574 Gene3D G3DSA:3.30.300.30 444 556 1.7E-21 T 29-03-2018 SMALA_RS41835 47a2c4ffd6f6bdff97fbde804cb5bddf 574 Gene3D G3DSA:2.30.38.10 353 443 1.1E-18 T 29-03-2018 SMALA_RS41835 47a2c4ffd6f6bdff97fbde804cb5bddf 574 Gene3D G3DSA:3.40.50.980 206 352 5.9E-34 T 29-03-2018 SMALA_RS41835 47a2c4ffd6f6bdff97fbde804cb5bddf 574 SUPERFAMILY SSF56801 34 548 3.66E-128 T 29-03-2018 SMALA_RS41835 47a2c4ffd6f6bdff97fbde804cb5bddf 574 ProSitePatterns PS00455 Putative AMP-binding domain signature. 201 212 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS41835 47a2c4ffd6f6bdff97fbde804cb5bddf 574 Pfam PF00501 AMP-binding enzyme 56 450 4.1E-74 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS01930 ea8ca0c2e958d061a78808194742bc5e 269 Gene3D G3DSA:1.10.3720.10 23 268 8.6E-32 T 29-03-2018 SMALA_RS01930 ea8ca0c2e958d061a78808194742bc5e 269 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 93 263 1.6E-25 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS01930 ea8ca0c2e958d061a78808194742bc5e 269 SUPERFAMILY SSF161098 69 255 4.45E-35 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS37220 0e31fcee11ae802459725e83380cc8d0 918 Pfam PF13191 AAA ATPase domain 7 153 4.7E-17 T 29-03-2018 SMALA_RS37220 0e31fcee11ae802459725e83380cc8d0 918 SUPERFAMILY SSF46894 845 907 2.14E-12 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS37220 0e31fcee11ae802459725e83380cc8d0 918 Gene3D G3DSA:1.25.40.10 269 415 0.011 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS37220 0e31fcee11ae802459725e83380cc8d0 918 Gene3D G3DSA:1.25.40.10 684 828 8.6E-4 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS37220 0e31fcee11ae802459725e83380cc8d0 918 SUPERFAMILY SSF52540 8 156 4.69E-9 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS37220 0e31fcee11ae802459725e83380cc8d0 918 Gene3D G3DSA:1.10.10.10 829 912 2.5E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS37220 0e31fcee11ae802459725e83380cc8d0 918 SMART SM00421 850 907 2.8E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS37220 0e31fcee11ae802459725e83380cc8d0 918 Pfam PF00196 Bacterial regulatory proteins, luxR family 853 904 3.0E-6 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS37220 0e31fcee11ae802459725e83380cc8d0 918 Gene3D G3DSA:1.25.40.10 513 683 0.075 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS37220 0e31fcee11ae802459725e83380cc8d0 918 Gene3D G3DSA:3.40.50.300 8 233 7.6E-11 T 29-03-2018 SMALA_RS07250 4b9b8f27d264ea99fa612b8c6d97501f 281 Gene3D G3DSA:3.60.20.10 47 275 7.6E-50 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SMALA_RS07250 4b9b8f27d264ea99fa612b8c6d97501f 281 TIGRFAM TIGR03690 20S_bact_beta: proteasome, beta subunit 50 269 7.8E-117 T 29-03-2018 IPR022483 Peptidase T1A, proteasome beta-subunit, actinobacteria GO:0004298|GO:0005839|GO:0010498 SMALA_RS07250 4b9b8f27d264ea99fa612b8c6d97501f 281 Hamap MF_02113_B Proteasome subunit beta [prcB]. 7 275 50.506 T 29-03-2018 IPR022483 Peptidase T1A, proteasome beta-subunit, actinobacteria GO:0004298|GO:0005839|GO:0010498 SMALA_RS07250 4b9b8f27d264ea99fa612b8c6d97501f 281 SUPERFAMILY SSF56235 47 265 1.2E-58 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SMALA_RS07250 4b9b8f27d264ea99fa612b8c6d97501f 281 PRINTS PR00141 Proteasome component signature 61 76 1.1E-6 T 29-03-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-446652|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8941858|Reactome: R-HSA-8951664|Reactome: R-HSA-983168 SMALA_RS07250 4b9b8f27d264ea99fa612b8c6d97501f 281 PRINTS PR00141 Proteasome component signature 188 199 1.1E-6 T 29-03-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-446652|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8941858|Reactome: R-HSA-8951664|Reactome: R-HSA-983168 SMALA_RS07250 4b9b8f27d264ea99fa612b8c6d97501f 281 PRINTS PR00141 Proteasome component signature 199 210 1.1E-6 T 29-03-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-446652|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8941858|Reactome: R-HSA-8951664|Reactome: R-HSA-983168 SMALA_RS07250 4b9b8f27d264ea99fa612b8c6d97501f 281 Pfam PF00227 Proteasome subunit 52 230 1.1E-36 T 29-03-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-446652|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8941858|Reactome: R-HSA-8951664|Reactome: R-HSA-983168 SMALA_RS40845 0630c29d9e605f29e437161e058c17b2 312 Gene3D G3DSA:3.40.1190.20 1 306 2.9E-54 T 29-03-2018 IPR029056 Ribokinase-like SMALA_RS40845 0630c29d9e605f29e437161e058c17b2 312 Pfam PF00294 pfkB family carbohydrate kinase 2 289 4.5E-36 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB SMALA_RS40845 0630c29d9e605f29e437161e058c17b2 312 SUPERFAMILY SSF53613 2 297 2.34E-49 T 29-03-2018 IPR029056 Ribokinase-like SMALA_RS40845 0630c29d9e605f29e437161e058c17b2 312 PRINTS PR00990 Ribokinase signature 31 50 1.8E-8 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 SMALA_RS40845 0630c29d9e605f29e437161e058c17b2 312 PRINTS PR00990 Ribokinase signature 4 25 1.8E-8 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 SMALA_RS40845 0630c29d9e605f29e437161e058c17b2 312 PRINTS PR00990 Ribokinase signature 211 222 1.8E-8 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 SMALA_RS36995 17e1e690c3fcdbe240ad96080b769c1e 252 Pfam PF00392 Bacterial regulatory proteins, gntR family 21 79 9.7E-17 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS36995 17e1e690c3fcdbe240ad96080b769c1e 252 Gene3D G3DSA:1.20.120.530 76 234 1.2E-30 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS36995 17e1e690c3fcdbe240ad96080b769c1e 252 SUPERFAMILY SSF48008 86 218 1.52E-24 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS36995 17e1e690c3fcdbe240ad96080b769c1e 252 SUPERFAMILY SSF46785 12 83 1.92E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS36995 17e1e690c3fcdbe240ad96080b769c1e 252 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 39 53 1.1E-6 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS36995 17e1e690c3fcdbe240ad96080b769c1e 252 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 53 69 1.1E-6 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS36995 17e1e690c3fcdbe240ad96080b769c1e 252 SMART SM00895 89 213 3.7E-16 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS36995 17e1e690c3fcdbe240ad96080b769c1e 252 Gene3D G3DSA:1.10.10.10 2 75 2.7E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS36995 17e1e690c3fcdbe240ad96080b769c1e 252 Pfam PF07729 FCD domain 93 212 3.6E-24 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS36995 17e1e690c3fcdbe240ad96080b769c1e 252 SMART SM00345 21 79 6.0E-16 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS14670 0ba8f18440e64999f075309bd0e52ebb 261 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 29 259 2.9E-61 T 29-03-2018 SMALA_RS14670 0ba8f18440e64999f075309bd0e52ebb 261 SUPERFAMILY SSF51735 21 260 3.28E-77 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS14670 0ba8f18440e64999f075309bd0e52ebb 261 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 21 202 1.4E-6 T 29-03-2018 SMALA_RS14670 0ba8f18440e64999f075309bd0e52ebb 261 Gene3D G3DSA:3.40.50.720 1 261 4.4E-73 T 29-03-2018 SMALA_RS14670 0ba8f18440e64999f075309bd0e52ebb 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 22 39 2.8E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS14670 0ba8f18440e64999f075309bd0e52ebb 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 192 209 2.8E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS14670 0ba8f18440e64999f075309bd0e52ebb 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 225 245 2.8E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS14670 0ba8f18440e64999f075309bd0e52ebb 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 161 2.8E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS14670 0ba8f18440e64999f075309bd0e52ebb 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 98 109 2.8E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS14670 0ba8f18440e64999f075309bd0e52ebb 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 190 2.8E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS14670 0ba8f18440e64999f075309bd0e52ebb 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 159 4.1E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS14670 0ba8f18440e64999f075309bd0e52ebb 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 171 190 4.1E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS14670 0ba8f18440e64999f075309bd0e52ebb 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 98 109 4.1E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS14670 0ba8f18440e64999f075309bd0e52ebb 261 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 158 186 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMALA_RS24335 3e028572098eea344bb976494f5c8d0b 124 Pfam PF05973 Phage derived protein Gp49-like (DUF891) 15 92 6.9E-16 T 29-03-2018 IPR009241 Toxin HigB-like SMALA_RS24335 3e028572098eea344bb976494f5c8d0b 124 SUPERFAMILY SSF143011 5 84 8.63E-5 T 29-03-2018 IPR035095 Toxin RelE-like domain SMALA_RS24335 3e028572098eea344bb976494f5c8d0b 124 Gene3D G3DSA:3.30.2310.20 4 98 1.4E-5 T 29-03-2018 SMALA_RS38045 7d06a8f84270825981f0a2eb7d2603fa 325 Gene3D G3DSA:3.40.50.1100 44 144 3.3E-26 T 29-03-2018 SMALA_RS38045 7d06a8f84270825981f0a2eb7d2603fa 325 SUPERFAMILY SSF53686 4 308 3.7E-65 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMALA_RS38045 7d06a8f84270825981f0a2eb7d2603fa 325 PIRSF PIRSF006278 2 314 2.6E-74 T 29-03-2018 IPR027278 1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase SMALA_RS38045 7d06a8f84270825981f0a2eb7d2603fa 325 Gene3D G3DSA:3.40.50.1100 145 311 4.4E-20 T 29-03-2018 SMALA_RS38045 7d06a8f84270825981f0a2eb7d2603fa 325 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 7 296 3.9E-45 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMALA_RS06640 1cd28f6be5cfeb30dd92c0b3822f0dbe 153 SUPERFAMILY SSF46785 9 145 1.73E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS06640 1cd28f6be5cfeb30dd92c0b3822f0dbe 153 Pfam PF01047 MarR family 39 87 5.9E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS06640 1cd28f6be5cfeb30dd92c0b3822f0dbe 153 Gene3D G3DSA:1.10.10.10 2 153 2.3E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS06640 1cd28f6be5cfeb30dd92c0b3822f0dbe 153 SMART SM00347 31 131 1.1E-18 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS17845 5b7a1347905381125f5766a7f6592456 324 Gene3D G3DSA:3.40.190.10 81 209 6.3E-16 T 29-03-2018 SMALA_RS17845 5b7a1347905381125f5766a7f6592456 324 SUPERFAMILY SSF53850 5 131 6.3E-18 T 29-03-2018 SMALA_RS17845 5b7a1347905381125f5766a7f6592456 324 SUPERFAMILY SSF53850 160 312 6.3E-18 T 29-03-2018 SMALA_RS36110 f76425d696d8cd962ba502b3309aae62 548 Gene3D G3DSA:1.20.140.10 271 443 3.9E-34 T 29-03-2018 SMALA_RS36110 f76425d696d8cd962ba502b3309aae62 548 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 177 270 2.3E-16 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 SMALA_RS36110 f76425d696d8cd962ba502b3309aae62 548 SUPERFAMILY SSF56645 57 290 1.31E-38 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMALA_RS36110 f76425d696d8cd962ba502b3309aae62 548 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 396 415 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 SMALA_RS36110 f76425d696d8cd962ba502b3309aae62 548 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 281 437 8.9E-30 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMALA_RS36110 f76425d696d8cd962ba502b3309aae62 548 Gene3D G3DSA:2.40.110.10 174 270 6.2E-25 T 29-03-2018 SMALA_RS36110 f76425d696d8cd962ba502b3309aae62 548 SUPERFAMILY SSF47203 286 440 4.83E-39 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMALA_RS25990 57535b5927c7700acdcafe943dde6b3e 134 Gene3D G3DSA:1.10.10.10 24 134 1.8E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS25990 57535b5927c7700acdcafe943dde6b3e 134 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 28 87 1.4E-17 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 SMALA_RS25990 57535b5927c7700acdcafe943dde6b3e 134 SUPERFAMILY SSF46767 27 86 3.66E-14 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 SMALA_RS04560 bbc6372e37e2a48708fa8acbb39bc6e2 154 Gene3D G3DSA:1.10.10.10 1 135 1.7E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS04560 bbc6372e37e2a48708fa8acbb39bc6e2 154 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 2 130 3.9E-33 T 29-03-2018 IPR000944 Transcription regulator Rrf2-type SMALA_RS04560 bbc6372e37e2a48708fa8acbb39bc6e2 154 SUPERFAMILY SSF46785 2 131 6.49E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS04560 bbc6372e37e2a48708fa8acbb39bc6e2 154 Pfam PF02082 Transcriptional regulator 2 81 7.5E-24 T 29-03-2018 IPR000944 Transcription regulator Rrf2-type SMALA_RS26845 24099e5f15d77898124ca6a8f84c36d8 374 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 112 268 3.2E-53 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain SMALA_RS26845 24099e5f15d77898124ca6a8f84c36d8 374 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 112 268 5.7E-47 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain SMALA_RS29175 6558189f0c39798b52f15da63728aa60 383 Gene3D G3DSA:3.40.50.1400 10 168 1.9E-28 T 29-03-2018 SMALA_RS29175 6558189f0c39798b52f15da63728aa60 383 Pfam PF00762 Ferrochelatase 14 335 7.1E-92 T 29-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 SMALA_RS29175 6558189f0c39798b52f15da63728aa60 383 Hamap MF_00323 Ferrochelatase [hemH]. 12 336 29.965 T 29-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 SMALA_RS29175 6558189f0c39798b52f15da63728aa60 383 SUPERFAMILY SSF53800 12 339 2.62E-79 T 29-03-2018 SMALA_RS29175 6558189f0c39798b52f15da63728aa60 383 Gene3D G3DSA:3.40.50.1400 169 317 9.5E-46 T 29-03-2018 SMALA_RS04665 26f9d1d8bc75267b45f79e9117d2b3d2 374 Gene3D G3DSA:3.30.9.10 81 157 8.8E-4 T 29-03-2018 SMALA_RS04665 26f9d1d8bc75267b45f79e9117d2b3d2 374 Gene3D G3DSA:3.50.50.60 1 77 2.0E-4 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS04665 26f9d1d8bc75267b45f79e9117d2b3d2 374 Gene3D G3DSA:3.30.9.10 158 331 4.5E-20 T 29-03-2018 SMALA_RS04665 26f9d1d8bc75267b45f79e9117d2b3d2 374 SUPERFAMILY SSF51905 2 213 3.11E-35 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS04665 26f9d1d8bc75267b45f79e9117d2b3d2 374 SUPERFAMILY SSF51905 332 372 3.11E-35 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS04665 26f9d1d8bc75267b45f79e9117d2b3d2 374 Pfam PF01266 FAD dependent oxidoreductase 2 370 6.3E-45 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 SMALA_RS04665 26f9d1d8bc75267b45f79e9117d2b3d2 374 TIGRFAM TIGR03364 HpnW_proposed: FAD dependent oxidoreductase TIGR03364 2 366 1.0E-98 T 29-03-2018 IPR017741 FAD-dependent oxidoreductase, HpnW SMALA_RS16415 86364e563856b46cefcaa7cfed0d5778 287 Gene3D G3DSA:3.40.605.10 1 257 2.1E-58 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS16415 86364e563856b46cefcaa7cfed0d5778 287 Pfam PF00171 Aldehyde dehydrogenase family 24 255 9.7E-42 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS16415 86364e563856b46cefcaa7cfed0d5778 287 SUPERFAMILY SSF53720 7 256 6.54E-45 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMALA_RS40085 619c6f4963742b1d67d20001b82c082d 256 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 148 176 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMALA_RS40085 619c6f4963742b1d67d20001b82c082d 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 88 99 8.8E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40085 619c6f4963742b1d67d20001b82c082d 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 161 180 8.8E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40085 619c6f4963742b1d67d20001b82c082d 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 8.8E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40085 619c6f4963742b1d67d20001b82c082d 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 29 253 3.9E-57 T 29-03-2018 SMALA_RS40085 619c6f4963742b1d67d20001b82c082d 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 1.5E-43 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40085 619c6f4963742b1d67d20001b82c082d 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 1.5E-43 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40085 619c6f4963742b1d67d20001b82c082d 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 1.5E-43 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40085 619c6f4963742b1d67d20001b82c082d 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 1.5E-43 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40085 619c6f4963742b1d67d20001b82c082d 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 1.5E-43 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40085 619c6f4963742b1d67d20001b82c082d 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 24 41 1.5E-43 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40085 619c6f4963742b1d67d20001b82c082d 256 SUPERFAMILY SSF51735 22 253 1.84E-75 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS40085 619c6f4963742b1d67d20001b82c082d 256 Gene3D G3DSA:3.40.50.720 16 59 6.4E-9 T 29-03-2018 SMALA_RS40085 619c6f4963742b1d67d20001b82c082d 256 Gene3D G3DSA:3.40.50.720 60 255 4.2E-61 T 29-03-2018 SMALA_RS22880 8932ca74e14a183e276662ea2bef9c7e 276 Gene3D G3DSA:3.30.2140.10 4 142 5.0E-37 T 29-03-2018 SMALA_RS22880 8932ca74e14a183e276662ea2bef9c7e 276 Gene3D G3DSA:3.30.2140.10 148 274 3.0E-17 T 29-03-2018 SMALA_RS22880 8932ca74e14a183e276662ea2bef9c7e 276 SUPERFAMILY SSF54001 6 270 8.83E-74 T 29-03-2018 SMALA_RS22880 8932ca74e14a183e276662ea2bef9c7e 276 Pfam PF00797 N-acetyltransferase 26 269 1.9E-64 T 29-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 SMALA_RS22880 8932ca74e14a183e276662ea2bef9c7e 276 PRINTS PR01543 Arylamine N-acetyltransferase signature 74 96 3.0E-13 T 29-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 SMALA_RS22880 8932ca74e14a183e276662ea2bef9c7e 276 PRINTS PR01543 Arylamine N-acetyltransferase signature 185 207 3.0E-13 T 29-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 SMALA_RS22880 8932ca74e14a183e276662ea2bef9c7e 276 PRINTS PR01543 Arylamine N-acetyltransferase signature 26 49 3.0E-13 T 29-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 SMALA_RS22880 8932ca74e14a183e276662ea2bef9c7e 276 PRINTS PR01543 Arylamine N-acetyltransferase signature 50 73 3.0E-13 T 29-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 SMALA_RS00240 5d32ce22724f0145fcba4f6cac614367 341 SUPERFAMILY SSF46785 6 66 2.29E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS00240 5d32ce22724f0145fcba4f6cac614367 341 ProSitePatterns PS00894 DeoR-type HTH domain signature. 10 44 - T 29-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 SMALA_RS00240 5d32ce22724f0145fcba4f6cac614367 341 Pfam PF08279 HTH domain 10 65 3.3E-17 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 SMALA_RS00240 5d32ce22724f0145fcba4f6cac614367 341 Gene3D G3DSA:1.10.10.10 3 69 4.6E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS00240 5d32ce22724f0145fcba4f6cac614367 341 Pfam PF13280 WYL domain 145 324 5.4E-29 T 29-03-2018 IPR026881 WYL domain SMALA_RS00240 5d32ce22724f0145fcba4f6cac614367 341 PIRSF PIRSF016838 69 237 1.1E-14 T 29-03-2018 IPR028349 Protein PafC SMALA_RS00240 5d32ce22724f0145fcba4f6cac614367 341 PIRSF PIRSF016838 2 62 0.012 T 29-03-2018 IPR028349 Protein PafC SMALA_RS00240 5d32ce22724f0145fcba4f6cac614367 341 PIRSF PIRSF016838 261 331 9.3 T 29-03-2018 IPR028349 Protein PafC SMALA_RS11550 d080e42703ff6563a36cd88d108fd190 394 SMART SM00530 12 67 5.4E-7 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS11550 d080e42703ff6563a36cd88d108fd190 394 Gene3D G3DSA:1.25.40.10 88 381 8.8E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS11550 d080e42703ff6563a36cd88d108fd190 394 Gene3D G3DSA:1.10.260.40 5 71 4.8E-13 T 29-03-2018 SMALA_RS11550 d080e42703ff6563a36cd88d108fd190 394 Pfam PF13560 Helix-turn-helix domain 10 65 2.7E-9 T 29-03-2018 SMALA_RS11550 d080e42703ff6563a36cd88d108fd190 394 SUPERFAMILY SSF47413 6 69 6.97E-11 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS24205 56c1599cb5c56863915db9d2be9f6330 92 Gene3D G3DSA:1.10.1220.10 1 82 8.3E-6 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 SMALA_RS24205 56c1599cb5c56863915db9d2be9f6330 92 SUPERFAMILY SSF47598 4 60 2.22E-7 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 SMALA_RS07525 31978d941b933d462ca9d76887e5fd44 337 Gene3D G3DSA:1.10.10.10 13 324 2.7E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS07525 31978d941b933d462ca9d76887e5fd44 337 Pfam PF13814 Replication-relaxation 51 239 3.6E-39 T 29-03-2018 IPR025855 Plasmid replication-relaxation SMALA_RS29570 3884cafcfb615b7867fa29a37792f2c2 722 SUPERFAMILY SSF82866 140 343 1.24E-32 T 29-03-2018 SMALA_RS29570 3884cafcfb615b7867fa29a37792f2c2 722 Gene3D G3DSA:1.20.1640.10 74 340 4.3E-37 T 29-03-2018 SMALA_RS29570 3884cafcfb615b7867fa29a37792f2c2 722 Gene3D G3DSA:1.20.1640.10 469 697 9.2E-32 T 29-03-2018 SMALA_RS29570 3884cafcfb615b7867fa29a37792f2c2 722 Pfam PF03176 MMPL family 43 368 4.5E-59 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 SMALA_RS29570 3884cafcfb615b7867fa29a37792f2c2 722 Pfam PF03176 MMPL family 397 697 2.3E-54 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 SMALA_RS29570 3884cafcfb615b7867fa29a37792f2c2 722 SUPERFAMILY SSF82866 490 692 3.14E-33 T 29-03-2018 SMALA_RS41210 40b2c3d1b324f7f028003c119924c22e 329 SUPERFAMILY SSF52540 1 51 1.99E-23 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS41210 40b2c3d1b324f7f028003c119924c22e 329 SUPERFAMILY SSF52540 86 240 1.99E-23 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS41210 40b2c3d1b324f7f028003c119924c22e 329 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 7 100 6.4E-8 T 29-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain SMALA_RS41210 40b2c3d1b324f7f028003c119924c22e 329 Gene3D G3DSA:3.40.50.300 1 288 2.0E-36 T 29-03-2018 SMALA_RS21860 d1f5fd634db1de858c0d35050899b998 499 Pfam PF08386 TAP-like protein 403 497 6.6E-21 T 29-03-2018 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal SMALA_RS21860 d1f5fd634db1de858c0d35050899b998 499 Pfam PF00561 alpha/beta hydrolase fold 93 287 5.7E-21 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS21860 d1f5fd634db1de858c0d35050899b998 499 SUPERFAMILY SSF53474 303 485 4.35E-20 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS21860 d1f5fd634db1de858c0d35050899b998 499 SUPERFAMILY SSF53474 70 137 4.35E-20 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS21860 d1f5fd634db1de858c0d35050899b998 499 SUPERFAMILY SSF53474 177 241 4.35E-20 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS21860 d1f5fd634db1de858c0d35050899b998 499 Gene3D G3DSA:3.40.50.1820 52 487 4.8E-37 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS17835 4e69af6954df492e708b352617fcd85c 341 SUPERFAMILY SSF51430 1 316 1.28E-94 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS17835 4e69af6954df492e708b352617fcd85c 341 Gene3D G3DSA:3.20.20.100 1 318 5.2E-88 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS17835 4e69af6954df492e708b352617fcd85c 341 Pfam PF00248 Aldo/keto reductase family 18 315 1.3E-72 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS17835 4e69af6954df492e708b352617fcd85c 341 PRINTS PR00069 Aldo-keto reductase signature 41 65 1.2E-8 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMALA_RS17835 4e69af6954df492e708b352617fcd85c 341 PRINTS PR00069 Aldo-keto reductase signature 105 123 1.2E-8 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMALA_RS17835 4e69af6954df492e708b352617fcd85c 341 PRINTS PR00069 Aldo-keto reductase signature 136 153 1.2E-8 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMALA_RS11015 0329e1ae62b338d85f1a2bc2e658eff2 251 SUPERFAMILY SSF51735 39 245 2.95E-40 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS11015 0329e1ae62b338d85f1a2bc2e658eff2 251 TIGRFAM TIGR01915 npdG: NADPH-dependent F420 reductase 38 248 7.8E-77 T 29-03-2018 IPR010185 NADPH-dependent F420 reductase GO:0006740|GO:0016651|GO:0050661|GO:0055114|GO:0070967 SMALA_RS11015 0329e1ae62b338d85f1a2bc2e658eff2 251 Gene3D G3DSA:3.40.50.720 34 240 5.9E-29 T 29-03-2018 SMALA_RS11015 0329e1ae62b338d85f1a2bc2e658eff2 251 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 40 134 7.0E-21 T 29-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal SMALA_RS31065 a3c5983c795ee19690d5a478e1668660 241 Gene3D G3DSA:2.40.260.10 32 241 9.1E-30 T 29-03-2018 IPR023365 Sortase domain SMALA_RS31065 a3c5983c795ee19690d5a478e1668660 241 Pfam PF04203 Sortase family 95 235 4.1E-17 T 29-03-2018 IPR005754 Sortase family SMALA_RS31065 a3c5983c795ee19690d5a478e1668660 241 SUPERFAMILY SSF63817 90 237 3.14E-15 T 29-03-2018 IPR023365 Sortase domain SMALA_RS41305 ba9fcf59c5985f80a2a2272899b7ee10 431 Pfam PF01590 GAF domain 39 186 7.0E-9 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS41305 ba9fcf59c5985f80a2a2272899b7ee10 431 Gene3D G3DSA:3.30.450.40 18 189 6.6E-28 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS41305 ba9fcf59c5985f80a2a2272899b7ee10 431 SUPERFAMILY SSF55781 39 196 1.13E-14 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS41305 ba9fcf59c5985f80a2a2272899b7ee10 431 SMART SM00331 213 430 7.2E-28 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS41305 ba9fcf59c5985f80a2a2272899b7ee10 431 Gene3D G3DSA:3.60.40.10 190 431 7.9E-34 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS41305 ba9fcf59c5985f80a2a2272899b7ee10 431 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 242 430 1.2E-40 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS41305 ba9fcf59c5985f80a2a2272899b7ee10 431 SMART SM00065 39 196 1.0E-7 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS12225 6b304284254bdb3e1832ee6861d12c0e 329 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 227 323 1.6E-15 T 29-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal SMALA_RS12225 6b304284254bdb3e1832ee6861d12c0e 329 Gene3D G3DSA:3.30.465.10 55 220 7.2E-33 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SMALA_RS12225 6b304284254bdb3e1832ee6861d12c0e 329 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 3 219 2.2E-49 T 29-03-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 SMALA_RS12225 6b304284254bdb3e1832ee6861d12c0e 329 Gene3D G3DSA:3.30.390.50 222 329 7.3E-24 T 29-03-2018 SMALA_RS12225 6b304284254bdb3e1832ee6861d12c0e 329 SUPERFAMILY SSF55447 224 324 4.58E-25 T 29-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal SMALA_RS12225 6b304284254bdb3e1832ee6861d12c0e 329 SUPERFAMILY SSF56176 1 219 2.18E-58 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SMALA_RS12225 6b304284254bdb3e1832ee6861d12c0e 329 SMART SM01092 226 324 1.5E-23 T 29-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal SMALA_RS12225 6b304284254bdb3e1832ee6861d12c0e 329 Gene3D G3DSA:3.30.43.10 1 51 2.3E-19 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 SMALA_RS01670 6dd55845413ff0b67715bc1f3b5e0fbd 513 PIRSF PIRSF002744 1 485 3.1E-103 T 29-03-2018 IPR026030 Purine-cytosine permease Fcy2/21/22 GO:0005215|GO:0016021|GO:0055085 SMALA_RS01670 6dd55845413ff0b67715bc1f3b5e0fbd 513 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 18 458 2.0E-44 T 29-03-2018 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 SMALA_RS20915 61a6124c1fc76fdae994bdf7ee171351 132 SUPERFAMILY SSF54427 1 130 1.71E-21 T 29-03-2018 IPR032710 NTF2-like domain SMALA_RS20915 61a6124c1fc76fdae994bdf7ee171351 132 Gene3D G3DSA:3.10.450.50 5 127 1.8E-16 T 29-03-2018 SMALA_RS20915 61a6124c1fc76fdae994bdf7ee171351 132 Pfam PF12680 SnoaL-like domain 10 115 1.3E-12 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain SMALA_RS34450 8f2ccc7116bbc8a986fcc08a61abb2f5 135 Pfam PF13380 CoA binding domain 18 131 1.9E-36 T 29-03-2018 IPR003781 CoA-binding GO:0048037 SMALA_RS34450 8f2ccc7116bbc8a986fcc08a61abb2f5 135 SMART SM00881 12 105 7.8E-19 T 29-03-2018 IPR003781 CoA-binding GO:0048037 SMALA_RS34450 8f2ccc7116bbc8a986fcc08a61abb2f5 135 SUPERFAMILY SSF51735 17 135 3.94E-37 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS34450 8f2ccc7116bbc8a986fcc08a61abb2f5 135 Gene3D G3DSA:3.40.50.720 14 134 4.5E-29 T 29-03-2018 SMALA_RS02845 c9014ee8410b7647606323249b6aeecd 372 SUPERFAMILY SSF51395 7 356 1.07E-96 T 29-03-2018 SMALA_RS02845 c9014ee8410b7647606323249b6aeecd 372 Gene3D G3DSA:3.20.20.70 2 363 1.4E-104 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS02845 c9014ee8410b7647606323249b6aeecd 372 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 11 357 3.3E-63 T 29-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 SMALA_RS42805 86e231af1d2277b7f515538cf0ffad16 458 Gene3D G3DSA:1.10.260.40 355 432 1.2E-5 T 29-03-2018 SMALA_RS42805 86e231af1d2277b7f515538cf0ffad16 458 Pfam PF13413 Helix-turn-helix domain 380 426 3.9E-6 T 29-03-2018 SMALA_RS12305 93d257a74aec623bde482a82609be02f 279 Gene3D G3DSA:3.30.420.40 27 148 4.9E-7 T 29-03-2018 SMALA_RS12305 93d257a74aec623bde482a82609be02f 279 Pfam PF06723 MreB/Mbl protein 61 166 2.3E-7 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 SMALA_RS12305 93d257a74aec623bde482a82609be02f 279 Pfam PF06723 MreB/Mbl protein 185 261 1.0E-7 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 SMALA_RS12305 93d257a74aec623bde482a82609be02f 279 Gene3D G3DSA:3.30.420.40 149 245 7.6E-11 T 29-03-2018 SMALA_RS12305 93d257a74aec623bde482a82609be02f 279 SUPERFAMILY SSF53067 145 258 8.91E-10 T 29-03-2018 SMALA_RS10275 09d702f273e12340dcb82a1250dd1cdc 810 Pfam PF01841 Transglutaminase-like superfamily 440 554 7.2E-25 T 29-03-2018 IPR002931 Transglutaminase-like SMALA_RS10275 09d702f273e12340dcb82a1250dd1cdc 810 Pfam PF13559 Domain of unknown function (DUF4129) 677 746 2.5E-5 T 29-03-2018 IPR025403 Domain of unknown function DUF4129 SMALA_RS10275 09d702f273e12340dcb82a1250dd1cdc 810 Gene3D G3DSA:3.90.260.10 425 573 3.1E-17 T 29-03-2018 IPR002931 Transglutaminase-like SMALA_RS10275 09d702f273e12340dcb82a1250dd1cdc 810 SUPERFAMILY SSF54001 422 561 3.5E-33 T 29-03-2018 SMALA_RS10275 09d702f273e12340dcb82a1250dd1cdc 810 SMART SM00460 486 556 4.7E-22 T 29-03-2018 IPR002931 Transglutaminase-like SMALA_RS01470 c2ad10195c67c01ce9488880b2d1ab22 954 ProSitePatterns PS00211 ABC transporters family signature. 855 869 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS01470 c2ad10195c67c01ce9488880b2d1ab22 954 TIGRFAM TIGR03797 NHLM_micro_ABC2: NHLM bacteriocin system ABC transporter, ATP-binding protein 271 952 7.8E-269 T 29-03-2018 IPR022515 NHPM bacteriocin system ABC transporter, ATP-binding protein SMALA_RS01470 c2ad10195c67c01ce9488880b2d1ab22 954 Pfam PF00005 ABC transporter 736 883 1.2E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS01470 c2ad10195c67c01ce9488880b2d1ab22 954 SUPERFAMILY SSF52540 712 944 1.36E-68 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS01470 c2ad10195c67c01ce9488880b2d1ab22 954 Pfam PF00664 ABC transporter transmembrane region 410 675 1.3E-17 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMALA_RS01470 c2ad10195c67c01ce9488880b2d1ab22 954 SMART SM00382 745 921 2.9E-20 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS01470 c2ad10195c67c01ce9488880b2d1ab22 954 Gene3D G3DSA:3.40.50.300 718 953 2.3E-65 T 29-03-2018 SMALA_RS01470 c2ad10195c67c01ce9488880b2d1ab22 954 SUPERFAMILY SSF90123 393 704 3.53E-38 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMALA_RS01470 c2ad10195c67c01ce9488880b2d1ab22 954 Gene3D G3DSA:1.20.1560.10 388 708 6.7E-33 T 29-03-2018 SMALA_RS39160 8c288ddde29defbd0629418ce5fcb8a6 246 Gene3D G3DSA:3.90.226.10 25 234 1.5E-19 T 29-03-2018 SMALA_RS39160 8c288ddde29defbd0629418ce5fcb8a6 246 Pfam PF00378 Enoyl-CoA hydratase/isomerase 78 218 3.6E-10 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 SMALA_RS39160 8c288ddde29defbd0629418ce5fcb8a6 246 SUPERFAMILY SSF52096 64 220 1.84E-20 T 29-03-2018 IPR029045 ClpP/crotonase-like domain SMALA_RS14045 45eae6f1e5d9708a409c0859f3864c3b 352 Gene3D G3DSA:3.40.50.2300 190 314 2.4E-43 T 29-03-2018 SMALA_RS14045 45eae6f1e5d9708a409c0859f3864c3b 352 Pfam PF13377 Periplasmic binding protein-like domain 184 347 1.9E-31 T 29-03-2018 SMALA_RS14045 45eae6f1e5d9708a409c0859f3864c3b 352 SUPERFAMILY SSF47413 2 60 4.88E-14 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS14045 45eae6f1e5d9708a409c0859f3864c3b 352 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 29-03-2018 SMALA_RS14045 45eae6f1e5d9708a409c0859f3864c3b 352 Gene3D G3DSA:1.10.260.40 3 62 2.6E-17 T 29-03-2018 SMALA_RS14045 45eae6f1e5d9708a409c0859f3864c3b 352 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 49 4.8E-15 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS14045 45eae6f1e5d9708a409c0859f3864c3b 352 SUPERFAMILY SSF53822 62 350 1.71E-59 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SMALA_RS14045 45eae6f1e5d9708a409c0859f3864c3b 352 SMART SM00354 2 72 2.6E-21 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS14045 45eae6f1e5d9708a409c0859f3864c3b 352 Gene3D G3DSA:3.40.50.2300 63 189 1.4E-32 T 29-03-2018 SMALA_RS32260 b99ea8974074667bfd7acdf6cab7302c 319 Gene3D G3DSA:3.40.1000.10 149 311 1.3E-12 T 29-03-2018 SMALA_RS32260 b99ea8974074667bfd7acdf6cab7302c 319 Pfam PF10708 Protein of unknown function (DUF2510) 5 40 1.7E-10 T 29-03-2018 IPR018929 Domain of unknown function DUF2510 SMALA_RS04305 845cfc7a6531a36f02be0217bdaf913e 267 Gene3D G3DSA:3.40.50.150 5 265 2.8E-30 T 29-03-2018 SMALA_RS04305 845cfc7a6531a36f02be0217bdaf913e 267 SUPERFAMILY SSF53335 22 248 1.82E-33 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS04305 845cfc7a6531a36f02be0217bdaf913e 267 Pfam PF13649 Methyltransferase domain 50 140 6.5E-16 T 29-03-2018 SMALA_RS41330 27592d447f40f125bc58c8dd1d321eba 337 SUPERFAMILY SSF53474 74 329 3.57E-59 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS41330 27592d447f40f125bc58c8dd1d321eba 337 Pfam PF07859 alpha/beta hydrolase fold 105 306 2.3E-59 T 29-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 SMALA_RS41330 27592d447f40f125bc58c8dd1d321eba 337 ProSitePatterns PS01173 Lipolytic enzymes "G-D-X-G" family, putative histidine active site. 105 121 - T 29-03-2018 IPR002168 Lipase, GDXG, putative histidine active site GO:0008152|GO:0016787 Reactome: R-HSA-163560 SMALA_RS41330 27592d447f40f125bc58c8dd1d321eba 337 ProSitePatterns PS01174 Lipolytic enzymes "G-D-X-G" family, putative serine active site. 172 184 - T 29-03-2018 IPR033140 Lipase, GDXG, putative serine active site SMALA_RS41330 27592d447f40f125bc58c8dd1d321eba 337 Gene3D G3DSA:3.40.50.1820 25 330 2.2E-50 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS41910 e62cf501593e3c54ab334c4a75786476 341 Gene3D G3DSA:1.10.3720.10 21 330 1.7E-28 T 29-03-2018 SMALA_RS41910 e62cf501593e3c54ab334c4a75786476 341 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 138 336 4.5E-30 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS41910 e62cf501593e3c54ab334c4a75786476 341 SUPERFAMILY SSF161098 113 319 5.1E-13 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS26320 4e37ec4b42083d6880d7a89009b1e761 356 Gene3D G3DSA:3.40.50.10490 204 356 2.6E-35 T 29-03-2018 SMALA_RS26320 4e37ec4b42083d6880d7a89009b1e761 356 Gene3D G3DSA:3.40.50.10490 3 203 7.6E-36 T 29-03-2018 SMALA_RS26320 4e37ec4b42083d6880d7a89009b1e761 356 Pfam PF01380 SIS domain 54 176 2.3E-16 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 SMALA_RS26320 4e37ec4b42083d6880d7a89009b1e761 356 Pfam PF01380 SIS domain 213 338 4.3E-15 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 SMALA_RS26320 4e37ec4b42083d6880d7a89009b1e761 356 SUPERFAMILY SSF53697 17 354 3.07E-71 T 29-03-2018 SMALA_RS22050 024fa9d4f3a28676414ab7f8916583cb 148 Gene3D G3DSA:2.60.120.10 2 148 2.9E-57 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SMALA_RS22050 024fa9d4f3a28676414ab7f8916583cb 148 SUPERFAMILY SSF51182 8 147 9.83E-54 T 29-03-2018 IPR011051 RmlC-like cupin domain SMALA_RS22050 024fa9d4f3a28676414ab7f8916583cb 148 Pfam PF06172 Cupin superfamily (DUF985) 11 145 1.7E-48 T 29-03-2018 IPR009327 Cupin domain of unknown function DUF985 SMALA_RS02655 1173f2bc0de76a72c83dc702040b12a4 291 SUPERFAMILY SSF161098 17 291 3.92E-60 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS02655 1173f2bc0de76a72c83dc702040b12a4 291 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 106 283 9.5E-18 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS02655 1173f2bc0de76a72c83dc702040b12a4 291 Gene3D G3DSA:1.10.3720.10 10 278 2.8E-37 T 29-03-2018 SMALA_RS00990 cc24d1e4853f6f1aa10ed27b1c20b970 447 Pfam PF02983 Alpha-lytic protease prodomain 106 159 7.0E-14 T 29-03-2018 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 SMALA_RS00990 cc24d1e4853f6f1aa10ed27b1c20b970 447 Gene3D G3DSA:2.40.10.10 178 262 1.7E-20 T 29-03-2018 SMALA_RS00990 cc24d1e4853f6f1aa10ed27b1c20b970 447 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 288 305 4.1E-41 T 29-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMALA_RS00990 cc24d1e4853f6f1aa10ed27b1c20b970 447 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 204 218 4.1E-41 T 29-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMALA_RS00990 cc24d1e4853f6f1aa10ed27b1c20b970 447 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 267 287 4.1E-41 T 29-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMALA_RS00990 cc24d1e4853f6f1aa10ed27b1c20b970 447 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 331 345 4.1E-41 T 29-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMALA_RS00990 cc24d1e4853f6f1aa10ed27b1c20b970 447 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 307 330 4.1E-41 T 29-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMALA_RS00990 cc24d1e4853f6f1aa10ed27b1c20b970 447 Gene3D G3DSA:3.30.300.50 37 102 8.3E-12 T 29-03-2018 IPR035070 Streptogrisin prodomain SMALA_RS00990 cc24d1e4853f6f1aa10ed27b1c20b970 447 Pfam PF00089 Trypsin 202 359 1.4E-10 T 29-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 SMALA_RS00990 cc24d1e4853f6f1aa10ed27b1c20b970 447 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 206 211 - T 29-03-2018 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 SMALA_RS00990 cc24d1e4853f6f1aa10ed27b1c20b970 447 SUPERFAMILY SSF50494 181 361 3.53E-37 T 29-03-2018 IPR009003 Peptidase S1, PA clan SMALA_RS00990 cc24d1e4853f6f1aa10ed27b1c20b970 447 PIRSF PIRSF001134 1 367 1.8E-113 T 29-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMALA_RS00990 cc24d1e4853f6f1aa10ed27b1c20b970 447 PIRSF PIRSF001134 388 417 880.0 T 29-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMALA_RS00990 cc24d1e4853f6f1aa10ed27b1c20b970 447 Gene3D G3DSA:2.40.10.10 263 353 3.3E-22 T 29-03-2018 SMALA_RS00990 cc24d1e4853f6f1aa10ed27b1c20b970 447 Gene3D G3DSA:3.30.300.50 103 172 1.1E-16 T 29-03-2018 IPR035070 Streptogrisin prodomain SMALA_RS00990 cc24d1e4853f6f1aa10ed27b1c20b970 447 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 316 327 - T 29-03-2018 IPR033116 Serine proteases, trypsin family, serine active site SMALA_RS26660 06de1508ce60d1cc7cbc77f327b3522b 170 Pfam PF00583 Acetyltransferase (GNAT) family 23 133 2.8E-11 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SMALA_RS26660 06de1508ce60d1cc7cbc77f327b3522b 170 SUPERFAMILY SSF55729 2 141 4.49E-19 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS26660 06de1508ce60d1cc7cbc77f327b3522b 170 Gene3D G3DSA:3.40.630.30 1 170 4.7E-21 T 29-03-2018 SMALA_RS33780 d3597d761a110fe4cc0f65b150d67f72 151 Gene3D G3DSA:3.40.30.10 1 150 2.7E-35 T 29-03-2018 SMALA_RS33780 d3597d761a110fe4cc0f65b150d67f72 151 Pfam PF00578 AhpC/TSA family 3 125 4.4E-31 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 SMALA_RS33780 d3597d761a110fe4cc0f65b150d67f72 151 SUPERFAMILY SSF52833 3 147 1.78E-42 T 29-03-2018 IPR012336 Thioredoxin-like fold SMALA_RS33780 d3597d761a110fe4cc0f65b150d67f72 151 PIRSF PIRSF000239 1 150 1.3E-21 T 29-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 SMALA_RS17550 0403360026799458223927028db0b065 419 Pfam PF01979 Amidohydrolase family 84 413 2.6E-29 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 SMALA_RS17550 0403360026799458223927028db0b065 419 SUPERFAMILY SSF51338 384 415 4.82E-14 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS17550 0403360026799458223927028db0b065 419 SUPERFAMILY SSF51338 5 61 4.82E-14 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS17550 0403360026799458223927028db0b065 419 Gene3D G3DSA:2.30.40.10 4 100 5.9E-16 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS17550 0403360026799458223927028db0b065 419 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 74 410 4.8E-79 T 29-03-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 SMALA_RS17550 0403360026799458223927028db0b065 419 Gene3D G3DSA:3.20.20.140 101 384 1.5E-102 T 29-03-2018 SMALA_RS17550 0403360026799458223927028db0b065 419 PIRSF PIRSF038994 60 416 3.6E-108 T 29-03-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 SMALA_RS17550 0403360026799458223927028db0b065 419 SUPERFAMILY SSF51556 87 384 4.01E-89 T 29-03-2018 IPR032466 Metal-dependent hydrolase SMALA_RS42210 758a13b0af2d249230f2a261683dcbb6 365 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 5 337 5.5E-69 T 29-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 SMALA_RS42210 758a13b0af2d249230f2a261683dcbb6 365 Gene3D G3DSA:3.20.20.70 1 365 5.5E-103 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS42210 758a13b0af2d249230f2a261683dcbb6 365 SUPERFAMILY SSF51395 1 362 5.5E-98 T 29-03-2018 SMALA_RS26740 b0ee83b41c4c3c68d0d9ce56a4e95966 358 ProSitePatterns PS00559 Eukaryotic molybdopterin oxidoreductases signature. 57 91 - T 29-03-2018 IPR022407 Oxidoreductase, molybdopterin binding site GO:0043546|GO:0055114 SMALA_RS26740 b0ee83b41c4c3c68d0d9ce56a4e95966 358 Pfam PF00174 Oxidoreductase molybdopterin binding domain 40 214 2.3E-59 T 29-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 SMALA_RS26740 b0ee83b41c4c3c68d0d9ce56a4e95966 358 SUPERFAMILY SSF56524 5 228 8.89E-69 T 29-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 SMALA_RS26740 b0ee83b41c4c3c68d0d9ce56a4e95966 358 Gene3D G3DSA:3.90.420.10 2 235 1.0E-73 T 29-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 SMALA_RS26740 b0ee83b41c4c3c68d0d9ce56a4e95966 358 SUPERFAMILY SSF81296 243 355 2.73E-30 T 29-03-2018 IPR014756 Immunoglobulin E-set SMALA_RS26740 b0ee83b41c4c3c68d0d9ce56a4e95966 358 Gene3D G3DSA:2.60.40.650 242 358 9.1E-30 T 29-03-2018 SMALA_RS26740 b0ee83b41c4c3c68d0d9ce56a4e95966 358 PRINTS PR00407 Eukaryotic molybdopterin domain signature 8 22 4.8E-36 T 29-03-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 SMALA_RS26740 b0ee83b41c4c3c68d0d9ce56a4e95966 358 PRINTS PR00407 Eukaryotic molybdopterin domain signature 80 91 4.8E-36 T 29-03-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 SMALA_RS26740 b0ee83b41c4c3c68d0d9ce56a4e95966 358 PRINTS PR00407 Eukaryotic molybdopterin domain signature 107 122 4.8E-36 T 29-03-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 SMALA_RS26740 b0ee83b41c4c3c68d0d9ce56a4e95966 358 PRINTS PR00407 Eukaryotic molybdopterin domain signature 194 207 4.8E-36 T 29-03-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 SMALA_RS26740 b0ee83b41c4c3c68d0d9ce56a4e95966 358 PRINTS PR00407 Eukaryotic molybdopterin domain signature 178 191 4.8E-36 T 29-03-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 SMALA_RS26740 b0ee83b41c4c3c68d0d9ce56a4e95966 358 PRINTS PR00407 Eukaryotic molybdopterin domain signature 161 177 4.8E-36 T 29-03-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 SMALA_RS26740 b0ee83b41c4c3c68d0d9ce56a4e95966 358 PRINTS PR00407 Eukaryotic molybdopterin domain signature 337 350 4.8E-36 T 29-03-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 SMALA_RS26740 b0ee83b41c4c3c68d0d9ce56a4e95966 358 PRINTS PR00407 Eukaryotic molybdopterin domain signature 264 278 4.8E-36 T 29-03-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 SMALA_RS26740 b0ee83b41c4c3c68d0d9ce56a4e95966 358 PRINTS PR00407 Eukaryotic molybdopterin domain signature 278 290 4.8E-36 T 29-03-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 SMALA_RS26740 b0ee83b41c4c3c68d0d9ce56a4e95966 358 PRINTS PR00407 Eukaryotic molybdopterin domain signature 28 44 4.8E-36 T 29-03-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 SMALA_RS26740 b0ee83b41c4c3c68d0d9ce56a4e95966 358 Pfam PF03404 Mo-co oxidoreductase dimerisation domain 244 352 4.5E-17 T 29-03-2018 IPR005066 Moybdenum cofactor oxidoreductase, dimerisation GO:0016491|GO:0030151|GO:0055114 Reactome: R-HSA-1614517 SMALA_RS12750 6f910a9ed784cef08269664817d430c8 390 PIRSF PIRSF001112 3 387 9.3E-108 T 29-03-2018 IPR016292 Epoxide hydrolase GO:0033961 KEGG: 00980+3.3.2.9|Reactome: R-HSA-211945 SMALA_RS12750 6f910a9ed784cef08269664817d430c8 390 Gene3D G3DSA:3.40.50.1820 3 390 5.7E-73 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS12750 6f910a9ed784cef08269664817d430c8 390 SUPERFAMILY SSF53474 8 382 5.52E-93 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS12750 6f910a9ed784cef08269664817d430c8 390 PRINTS PR00412 Epoxide hydrolase signature 359 381 9.4E-12 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS12750 6f910a9ed784cef08269664817d430c8 390 PRINTS PR00412 Epoxide hydrolase signature 137 152 9.4E-12 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS12750 6f910a9ed784cef08269664817d430c8 390 PRINTS PR00412 Epoxide hydrolase signature 182 195 9.4E-12 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS12750 6f910a9ed784cef08269664817d430c8 390 PRINTS PR00412 Epoxide hydrolase signature 111 129 9.4E-12 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS12750 6f910a9ed784cef08269664817d430c8 390 PRINTS PR00412 Epoxide hydrolase signature 327 343 9.4E-12 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS12750 6f910a9ed784cef08269664817d430c8 390 Pfam PF06441 Epoxide hydrolase N terminus 10 120 2.2E-31 T 29-03-2018 IPR010497 Epoxide hydrolase, N-terminal KEGG: 00980+3.3.2.9|Reactome: R-HSA-211945 SMALA_RS03240 087c874326c8062586b1762ca52401fb 234 Pfam PF00857 Isochorismatase family 29 214 8.2E-21 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SMALA_RS03240 087c874326c8062586b1762ca52401fb 234 Gene3D G3DSA:3.40.50.850 20 230 8.8E-29 T 29-03-2018 SMALA_RS03240 087c874326c8062586b1762ca52401fb 234 SUPERFAMILY SSF52499 15 222 7.2E-35 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SMALA_RS32265 3eabaf7a62b649b8a5289c91cae37495 398 Gene3D G3DSA:3.20.20.10 27 278 5.9E-42 T 29-03-2018 IPR029066 PLP-binding barrel SMALA_RS32265 3eabaf7a62b649b8a5289c91cae37495 398 Pfam PF01168 Alanine racemase, N-terminal domain 25 271 7.5E-17 T 29-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SMALA_RS32265 3eabaf7a62b649b8a5289c91cae37495 398 SUPERFAMILY SSF51419 26 274 1.68E-20 T 29-03-2018 IPR029066 PLP-binding barrel SMALA_RS42705 df70bcd4ce5d949370cf65d47ae6f499 375 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS42705 df70bcd4ce5d949370cf65d47ae6f499 375 Gene3D G3DSA:3.40.50.300 1 239 2.7E-69 T 29-03-2018 SMALA_RS42705 df70bcd4ce5d949370cf65d47ae6f499 375 Gene3D G3DSA:2.40.50.140 281 348 0.0017 T 29-03-2018 SMALA_RS42705 df70bcd4ce5d949370cf65d47ae6f499 375 SUPERFAMILY SSF50331 243 356 1.3E-8 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal SMALA_RS42705 df70bcd4ce5d949370cf65d47ae6f499 375 SMART SM00382 27 216 6.8E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS42705 df70bcd4ce5d949370cf65d47ae6f499 375 SUPERFAMILY SSF52540 3 246 2.85E-79 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS42705 df70bcd4ce5d949370cf65d47ae6f499 375 Pfam PF08402 TOBE domain 278 356 2.1E-9 T 29-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 SMALA_RS42705 df70bcd4ce5d949370cf65d47ae6f499 375 Pfam PF00005 ABC transporter 19 166 2.1E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS38460 e651bfdff10ca2ff386d7299a7d21f91 584 Gene3D G3DSA:2.30.38.10 389 462 2.1E-13 T 29-03-2018 SMALA_RS38460 e651bfdff10ca2ff386d7299a7d21f91 584 SUPERFAMILY SSF56801 28 331 7.98E-76 T 29-03-2018 SMALA_RS38460 e651bfdff10ca2ff386d7299a7d21f91 584 SUPERFAMILY SSF56801 386 565 7.98E-76 T 29-03-2018 SMALA_RS38460 e651bfdff10ca2ff386d7299a7d21f91 584 Pfam PF00501 AMP-binding enzyme 30 354 1.1E-36 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS38460 e651bfdff10ca2ff386d7299a7d21f91 584 Pfam PF00501 AMP-binding enzyme 389 468 5.4E-13 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS38460 e651bfdff10ca2ff386d7299a7d21f91 584 ProSitePatterns PS00455 Putative AMP-binding domain signature. 161 172 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS38460 e651bfdff10ca2ff386d7299a7d21f91 584 Gene3D G3DSA:3.40.50.980 167 334 3.5E-28 T 29-03-2018 SMALA_RS38460 e651bfdff10ca2ff386d7299a7d21f91 584 Gene3D G3DSA:3.40.50.980 4 166 5.5E-22 T 29-03-2018 SMALA_RS38460 e651bfdff10ca2ff386d7299a7d21f91 584 Gene3D G3DSA:3.30.300.30 464 562 1.4E-5 T 29-03-2018 SMALA_RS14405 85987a6d8be8ec0dfa4103f5d114051b 444 Gene3D G3DSA:3.40.190.10 49 258 1.1E-24 T 29-03-2018 SMALA_RS14405 85987a6d8be8ec0dfa4103f5d114051b 444 SUPERFAMILY SSF53850 48 439 1.45E-47 T 29-03-2018 SMALA_RS14405 85987a6d8be8ec0dfa4103f5d114051b 444 Gene3D G3DSA:3.40.190.10 259 399 6.3E-16 T 29-03-2018 SMALA_RS14405 85987a6d8be8ec0dfa4103f5d114051b 444 Pfam PF13416 Bacterial extracellular solute-binding protein 67 375 1.7E-29 T 29-03-2018 SMALA_RS23315 fb465315570e50f57993df6306323a5a 488 SUPERFAMILY SSF51445 41 390 7.37E-37 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS23315 fb465315570e50f57993df6306323a5a 488 Gene3D G3DSA:3.20.20.80 40 380 8.4E-69 T 29-03-2018 SMALA_RS23315 fb465315570e50f57993df6306323a5a 488 Gene3D G3DSA:2.60.40.1180 381 488 3.2E-19 T 29-03-2018 SMALA_RS23315 fb465315570e50f57993df6306323a5a 488 Pfam PF14587 O-Glycosyl hydrolase family 30 29 263 2.5E-10 T 29-03-2018 SMALA_RS12450 1d3762b17a0b79450a874fbb35686b65 436 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 340 349 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMALA_RS12450 1d3762b17a0b79450a874fbb35686b65 436 PRINTS PR00359 B-class P450 signature 195 217 1.0E-21 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS12450 1d3762b17a0b79450a874fbb35686b65 436 PRINTS PR00359 B-class P450 signature 144 160 1.0E-21 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS12450 1d3762b17a0b79450a874fbb35686b65 436 PRINTS PR00359 B-class P450 signature 291 318 1.0E-21 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS12450 1d3762b17a0b79450a874fbb35686b65 436 PRINTS PR00359 B-class P450 signature 98 109 1.0E-21 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS12450 1d3762b17a0b79450a874fbb35686b65 436 PRINTS PR00359 B-class P450 signature 161 176 1.0E-21 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS12450 1d3762b17a0b79450a874fbb35686b65 436 PRINTS PR00359 B-class P450 signature 338 347 1.0E-21 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS12450 1d3762b17a0b79450a874fbb35686b65 436 Gene3D G3DSA:1.10.630.10 4 400 1.3E-43 T 29-03-2018 SMALA_RS12450 1d3762b17a0b79450a874fbb35686b65 436 SUPERFAMILY SSF48264 15 398 6.42E-60 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS09380 9ce6112280f84b49459ec24c9940244b 474 Gene3D G3DSA:1.20.1250.20 267 462 1.8E-16 T 29-03-2018 SMALA_RS09380 9ce6112280f84b49459ec24c9940244b 474 SUPERFAMILY SSF103473 20 210 3.66E-53 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS09380 9ce6112280f84b49459ec24c9940244b 474 SUPERFAMILY SSF103473 262 458 3.66E-53 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS09380 9ce6112280f84b49459ec24c9940244b 474 Pfam PF07690 Major Facilitator Superfamily 31 422 3.6E-45 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS09380 9ce6112280f84b49459ec24c9940244b 474 Gene3D G3DSA:1.20.1250.20 16 221 5.6E-29 T 29-03-2018 SMALA_RS37025 034eb341e1d6b4b5f505d826b8821dbf 639 Pfam PF05954 Phage late control gene D protein (GPD) 58 339 4.3E-13 T 29-03-2018 SMALA_RS37025 034eb341e1d6b4b5f505d826b8821dbf 639 SUPERFAMILY SSF69279 27 184 3.15E-20 T 29-03-2018 SMALA_RS37025 034eb341e1d6b4b5f505d826b8821dbf 639 Gene3D G3DSA:2.40.50.260 375 481 5.8E-32 T 29-03-2018 SMALA_RS37025 034eb341e1d6b4b5f505d826b8821dbf 639 Gene3D G3DSA:3.55.50.10 106 206 1.5E-5 T 29-03-2018 SMALA_RS37025 034eb341e1d6b4b5f505d826b8821dbf 639 SUPERFAMILY SSF69255 379 452 2.49E-17 T 29-03-2018 SMALA_RS36390 f0032bf9029739e1aa87f98b838d9d04 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 96 107 7.5E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS36390 f0032bf9029739e1aa87f98b838d9d04 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 167 7.5E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS36390 f0032bf9029739e1aa87f98b838d9d04 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 21 38 7.5E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS36390 f0032bf9029739e1aa87f98b838d9d04 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 233 253 7.5E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS36390 f0032bf9029739e1aa87f98b838d9d04 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 196 7.5E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS36390 f0032bf9029739e1aa87f98b838d9d04 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 198 215 7.5E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS36390 f0032bf9029739e1aa87f98b838d9d04 279 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 26 270 2.6E-64 T 29-03-2018 SMALA_RS36390 f0032bf9029739e1aa87f98b838d9d04 279 Gene3D G3DSA:3.40.50.720 59 273 7.5E-63 T 29-03-2018 SMALA_RS36390 f0032bf9029739e1aa87f98b838d9d04 279 SUPERFAMILY SSF51735 17 271 1.47E-80 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS36390 f0032bf9029739e1aa87f98b838d9d04 279 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 20 213 0.0061 T 29-03-2018 SMALA_RS36390 f0032bf9029739e1aa87f98b838d9d04 279 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 177 196 2.1E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS36390 f0032bf9029739e1aa87f98b838d9d04 279 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 96 107 2.1E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS36390 f0032bf9029739e1aa87f98b838d9d04 279 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 165 2.1E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS36390 f0032bf9029739e1aa87f98b838d9d04 279 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 164 192 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMALA_RS36390 f0032bf9029739e1aa87f98b838d9d04 279 Gene3D G3DSA:3.40.50.10090 16 58 1.7E-8 T 29-03-2018 SMALA_RS04155 db6c4f48958a43b39ba8ca72686a85cb 218 Gene3D G3DSA:3.30.420.10 48 200 1.7E-9 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SMALA_RS04155 db6c4f48958a43b39ba8ca72686a85cb 218 Pfam PF13358 DDE superfamily endonuclease 16 168 1.2E-20 T 29-03-2018 SMALA_RS29515 ad463a481c2e00101c903d12de141c41 367 SUPERFAMILY SSF53901 208 364 2.94E-6 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS29515 ad463a481c2e00101c903d12de141c41 367 Gene3D G3DSA:3.40.47.10 9 245 1.4E-35 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS29515 ad463a481c2e00101c903d12de141c41 367 SUPERFAMILY SSF53901 9 234 4.51E-33 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS29515 ad463a481c2e00101c903d12de141c41 367 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 9 230 5.3E-19 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS34900 88229d7f7690322735e561c499ad5842 270 PIRSF PIRSF017393 1 270 5.5E-103 T 29-03-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type SMALA_RS34900 88229d7f7690322735e561c499ad5842 270 Gene3D G3DSA:3.40.50.150 1 270 1.2E-46 T 29-03-2018 SMALA_RS34900 88229d7f7690322735e561c499ad5842 270 Pfam PF04672 S-adenosyl methyltransferase 10 270 1.6E-102 T 29-03-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type SMALA_RS34900 88229d7f7690322735e561c499ad5842 270 SUPERFAMILY SSF53335 21 256 2.11E-41 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS05895 3754afee8e7b1ef9e6cdadcbadb21741 298 Pfam PF02353 Mycolic acid cyclopropane synthetase 82 203 3.5E-11 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS05895 3754afee8e7b1ef9e6cdadcbadb21741 298 SUPERFAMILY SSF53335 27 264 8.91E-33 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS05895 3754afee8e7b1ef9e6cdadcbadb21741 298 Gene3D G3DSA:3.40.50.150 53 298 4.1E-37 T 29-03-2018 SMALA_RS13535 dde11e65312767585b1dcb94e4f7d0cd 536 Gene3D G3DSA:3.40.50.300 26 443 1.2E-17 T 29-03-2018 SMALA_RS13535 dde11e65312767585b1dcb94e4f7d0cd 536 SUPERFAMILY SSF52540 39 251 6.89E-20 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS13535 dde11e65312767585b1dcb94e4f7d0cd 536 Pfam PF00350 Dynamin family 63 194 1.8E-8 T 29-03-2018 IPR022812 Dynamin superfamily SMALA_RS27400 c711cce756083ccb7f2c6922c3fd80dd 270 SUPERFAMILY SSF46785 14 84 3.82E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS27400 c711cce756083ccb7f2c6922c3fd80dd 270 Gene3D G3DSA:3.30.450.40 89 261 1.1E-33 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS27400 c711cce756083ccb7f2c6922c3fd80dd 270 SUPERFAMILY SSF55781 71 256 3.73E-33 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS27400 c711cce756083ccb7f2c6922c3fd80dd 270 Pfam PF01614 Bacterial transcriptional regulator 133 251 1.0E-15 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal SMALA_RS27400 c711cce756083ccb7f2c6922c3fd80dd 270 Pfam PF09339 IclR helix-turn-helix domain 16 65 8.3E-12 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMALA_RS27400 c711cce756083ccb7f2c6922c3fd80dd 270 Gene3D G3DSA:1.10.10.10 12 75 1.9E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS27400 c711cce756083ccb7f2c6922c3fd80dd 270 SMART SM00346 13 103 1.9E-10 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMALA_RS35420 5cd4b75b81b8cbdc9f2b5628d95ae763 725 SUPERFAMILY SSF49503 33 137 2.8E-11 T 29-03-2018 IPR008972 Cupredoxin SMALA_RS35420 5cd4b75b81b8cbdc9f2b5628d95ae763 725 Pfam PF06439 Domain of Unknown Function (DUF1080) 517 723 4.7E-30 T 29-03-2018 IPR010496 Domain of unknown function DUF1080 SMALA_RS35420 5cd4b75b81b8cbdc9f2b5628d95ae763 725 Gene3D G3DSA:2.60.40.10 160 227 2.5E-13 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS35420 5cd4b75b81b8cbdc9f2b5628d95ae763 725 Gene3D G3DSA:2.60.40.10 348 401 2.7E-16 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS35420 5cd4b75b81b8cbdc9f2b5628d95ae763 725 Gene3D G3DSA:2.60.40.10 254 321 5.8E-16 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS35420 5cd4b75b81b8cbdc9f2b5628d95ae763 725 ProSitePatterns PS00196 Type-1 copper (blue) proteins signature. 116 131 - T 29-03-2018 IPR028871 Blue (type 1) copper protein, binding site SMALA_RS35420 5cd4b75b81b8cbdc9f2b5628d95ae763 725 Pfam PF12245 Bacterial Ig-like domain (group 3) 303 321 0.4 T 29-03-2018 IPR022038 Bacterial Ig-like domain SMALA_RS35420 5cd4b75b81b8cbdc9f2b5628d95ae763 725 Pfam PF12245 Bacterial Ig-like domain (group 3) 211 227 0.29 T 29-03-2018 IPR022038 Bacterial Ig-like domain SMALA_RS35420 5cd4b75b81b8cbdc9f2b5628d95ae763 725 Pfam PF12245 Bacterial Ig-like domain (group 3) 401 411 2.1 T 29-03-2018 IPR022038 Bacterial Ig-like domain SMALA_RS35420 5cd4b75b81b8cbdc9f2b5628d95ae763 725 Gene3D G3DSA:2.60.40.420 16 137 7.6E-7 T 29-03-2018 IPR008972 Cupredoxin SMALA_RS35420 5cd4b75b81b8cbdc9f2b5628d95ae763 725 Gene3D G3DSA:2.60.120.560 515 725 5.1E-38 T 29-03-2018 SMALA_RS35420 5cd4b75b81b8cbdc9f2b5628d95ae763 725 Gene3D G3DSA:2.60.40.1310 402 461 0.0018 T 29-03-2018 SMALA_RS39980 759d32866ba181e31de69cd5d057798b 304 SUPERFAMILY SSF54909 60 142 6.44E-15 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel SMALA_RS39980 759d32866ba181e31de69cd5d057798b 304 Pfam PF03992 Antibiotic biosynthesis monooxygenase 64 135 1.7E-8 T 29-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain SMALA_RS39980 759d32866ba181e31de69cd5d057798b 304 Gene3D G3DSA:3.30.70.100 49 159 2.4E-13 T 29-03-2018 SMALA_RS39980 759d32866ba181e31de69cd5d057798b 304 Gene3D G3DSA:3.30.70.100 204 298 1.9E-7 T 29-03-2018 SMALA_RS39980 759d32866ba181e31de69cd5d057798b 304 SUPERFAMILY SSF54909 206 286 2.24E-10 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel SMALA_RS19545 a743712a330988ce5da8f658cbaa746f 112 TIGRFAM TIGR01068 thioredoxin: thioredoxin 13 110 2.7E-30 T 29-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 SMALA_RS19545 a743712a330988ce5da8f658cbaa746f 112 Pfam PF00085 Thioredoxin 9 109 1.1E-28 T 29-03-2018 IPR013766 Thioredoxin domain GO:0045454 SMALA_RS19545 a743712a330988ce5da8f658cbaa746f 112 Gene3D G3DSA:3.40.30.10 3 112 1.1E-29 T 29-03-2018 SMALA_RS19545 a743712a330988ce5da8f658cbaa746f 112 PRINTS PR00421 Thioredoxin family signature 28 36 2.8E-7 T 29-03-2018 SMALA_RS19545 a743712a330988ce5da8f658cbaa746f 112 PRINTS PR00421 Thioredoxin family signature 36 45 2.8E-7 T 29-03-2018 SMALA_RS19545 a743712a330988ce5da8f658cbaa746f 112 PRINTS PR00421 Thioredoxin family signature 76 87 2.8E-7 T 29-03-2018 SMALA_RS19545 a743712a330988ce5da8f658cbaa746f 112 ProSitePatterns PS00194 Thioredoxin family active site. 29 47 - T 29-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 SMALA_RS19545 a743712a330988ce5da8f658cbaa746f 112 PIRSF PIRSF000077 7 112 2.6E-35 T 29-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 SMALA_RS19545 a743712a330988ce5da8f658cbaa746f 112 SUPERFAMILY SSF52833 3 111 2.95E-34 T 29-03-2018 IPR012336 Thioredoxin-like fold SMALA_RS26480 1ce7af8bcdd96ca8bf5a74023e8bed87 317 SUPERFAMILY SSF53850 20 304 1.05E-53 T 29-03-2018 SMALA_RS26480 1ce7af8bcdd96ca8bf5a74023e8bed87 317 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 65 302 2.1E-59 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SMALA_RS26480 1ce7af8bcdd96ca8bf5a74023e8bed87 317 Gene3D G3DSA:3.40.190.10 178 249 5.3E-17 T 29-03-2018 SMALA_RS26480 1ce7af8bcdd96ca8bf5a74023e8bed87 317 Gene3D G3DSA:3.40.190.10 250 304 0.0022 T 29-03-2018 SMALA_RS26480 1ce7af8bcdd96ca8bf5a74023e8bed87 317 SMART SM00062 64 305 3.6E-47 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SMALA_RS26480 1ce7af8bcdd96ca8bf5a74023e8bed87 317 Gene3D G3DSA:3.40.190.10 56 177 1.7E-27 T 29-03-2018 SMALA_RS06615 0890e718e9fab8dc463599fcd66e83e1 272 Gene3D G3DSA:1.10.12.10 225 263 3.5E-5 T 29-03-2018 IPR014748 Crontonase, C-terminal SMALA_RS06615 0890e718e9fab8dc463599fcd66e83e1 272 Gene3D G3DSA:3.90.226.10 2 224 4.5E-56 T 29-03-2018 SMALA_RS06615 0890e718e9fab8dc463599fcd66e83e1 272 SUPERFAMILY SSF52096 9 262 7.71E-70 T 29-03-2018 IPR029045 ClpP/crotonase-like domain SMALA_RS06615 0890e718e9fab8dc463599fcd66e83e1 272 Pfam PF00378 Enoyl-CoA hydratase/isomerase 18 261 6.1E-50 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 SMALA_RS12320 b8507f47ef126aff416635cbc1c4bb29 323 Pfam PF03060 Nitronate monooxygenase 79 304 2.5E-33 T 29-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 SMALA_RS12320 b8507f47ef126aff416635cbc1c4bb29 323 Pfam PF03060 Nitronate monooxygenase 2 65 4.2E-13 T 29-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 SMALA_RS12320 b8507f47ef126aff416635cbc1c4bb29 323 Gene3D G3DSA:3.20.20.70 1 317 1.1E-45 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS12320 b8507f47ef126aff416635cbc1c4bb29 323 SUPERFAMILY SSF51412 2 311 5.34E-51 T 29-03-2018 SMALA_RS10285 20e32c6813a7705763f578db005571b5 260 Gene3D G3DSA:3.40.50.150 4 260 1.1E-41 T 29-03-2018 SMALA_RS10285 20e32c6813a7705763f578db005571b5 260 Pfam PF13489 Methyltransferase domain 18 206 3.3E-16 T 29-03-2018 SMALA_RS10285 20e32c6813a7705763f578db005571b5 260 SUPERFAMILY SSF53335 41 214 9.04E-31 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS37210 fd879638dbdbc49f865a45287fd058f8 168 Gene3D G3DSA:3.30.565.10 28 163 1.5E-10 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS37210 fd879638dbdbc49f865a45287fd058f8 168 Pfam PF13581 Histidine kinase-like ATPase domain 37 147 3.2E-9 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS37210 fd879638dbdbc49f865a45287fd058f8 168 SUPERFAMILY SSF55874 56 135 1.32E-7 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS14805 090995c08f4413d8b222088655bc26f1 133 SUPERFAMILY SSF55874 37 126 6.77E-5 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS14805 090995c08f4413d8b222088655bc26f1 133 Gene3D G3DSA:3.30.565.10 4 133 1.0E-10 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS35115 5ad0485416a547e88cd741d1f3a9a8da 452 Pfam PF13416 Bacterial extracellular solute-binding protein 64 366 2.0E-37 T 29-03-2018 SMALA_RS35115 5ad0485416a547e88cd741d1f3a9a8da 452 Gene3D G3DSA:3.40.190.10 41 159 0.0084 T 29-03-2018 SMALA_RS35115 5ad0485416a547e88cd741d1f3a9a8da 452 Gene3D G3DSA:3.40.190.10 160 445 2.5E-39 T 29-03-2018 SMALA_RS35115 5ad0485416a547e88cd741d1f3a9a8da 452 SUPERFAMILY SSF53850 52 437 2.74E-67 T 29-03-2018 SMALA_RS02160 04029af36ee8ef556c077d551f6da761 905 Pfam PF13191 AAA ATPase domain 2 177 1.4E-15 T 29-03-2018 SMALA_RS02160 04029af36ee8ef556c077d551f6da761 905 Gene3D G3DSA:1.25.40.10 374 517 4.0E-4 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS02160 04029af36ee8ef556c077d551f6da761 905 Gene3D G3DSA:3.40.50.300 5 193 2.5E-9 T 29-03-2018 SMALA_RS02160 04029af36ee8ef556c077d551f6da761 905 Pfam PF00196 Bacterial regulatory proteins, luxR family 844 896 5.4E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS02160 04029af36ee8ef556c077d551f6da761 905 Gene3D G3DSA:1.10.10.10 835 903 1.4E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS02160 04029af36ee8ef556c077d551f6da761 905 SMART SM00421 842 899 8.1E-17 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS02160 04029af36ee8ef556c077d551f6da761 905 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 859 875 2.5E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS02160 04029af36ee8ef556c077d551f6da761 905 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 875 887 2.5E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS02160 04029af36ee8ef556c077d551f6da761 905 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 845 859 2.5E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS02160 04029af36ee8ef556c077d551f6da761 905 Gene3D G3DSA:1.25.40.10 669 834 3.5E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS02160 04029af36ee8ef556c077d551f6da761 905 Gene3D G3DSA:1.25.40.10 533 668 2.7E-4 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS02160 04029af36ee8ef556c077d551f6da761 905 ProSitePatterns PS00622 LuxR-type HTH domain signature. 859 886 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS02160 04029af36ee8ef556c077d551f6da761 905 SUPERFAMILY SSF46894 832 897 2.21E-15 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS02160 04029af36ee8ef556c077d551f6da761 905 SUPERFAMILY SSF52540 18 66 3.3E-7 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS02160 04029af36ee8ef556c077d551f6da761 905 SUPERFAMILY SSF52540 95 186 3.3E-7 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS31460 563ee3799df3223b1c4248d1708ec157 113 Pfam PF03551 Transcriptional regulator PadR-like family 15 88 3.8E-19 T 29-03-2018 IPR005149 Transcription regulator PadR, N-terminal SMALA_RS31460 563ee3799df3223b1c4248d1708ec157 113 SUPERFAMILY SSF46785 12 99 2.24E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS31460 563ee3799df3223b1c4248d1708ec157 113 Gene3D G3DSA:1.10.10.10 3 104 2.8E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS24105 8b7c86d4b68be6bdda9bd8e0e91b2393 262 SMART SM00382 49 235 3.4E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS24105 8b7c86d4b68be6bdda9bd8e0e91b2393 262 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS24105 8b7c86d4b68be6bdda9bd8e0e91b2393 262 Gene3D G3DSA:3.40.50.300 17 260 4.2E-62 T 29-03-2018 SMALA_RS24105 8b7c86d4b68be6bdda9bd8e0e91b2393 262 Pfam PF00005 ABC transporter 40 186 1.2E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS24105 8b7c86d4b68be6bdda9bd8e0e91b2393 262 SUPERFAMILY SSF52540 23 239 2.92E-70 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS13950 300d55977e06abb2f80997b80fa81c14 505 Gene3D G3DSA:3.40.50.300 231 500 1.1E-37 T 29-03-2018 SMALA_RS13950 300d55977e06abb2f80997b80fa81c14 505 Gene3D G3DSA:3.40.50.300 1 228 8.3E-51 T 29-03-2018 SMALA_RS13950 300d55977e06abb2f80997b80fa81c14 505 Pfam PF00005 ABC transporter 14 163 9.7E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS13950 300d55977e06abb2f80997b80fa81c14 505 Pfam PF00005 ABC transporter 262 415 4.4E-19 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS13950 300d55977e06abb2f80997b80fa81c14 505 SMART SM00382 270 464 0.0014 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS13950 300d55977e06abb2f80997b80fa81c14 505 SMART SM00382 23 211 2.4E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS13950 300d55977e06abb2f80997b80fa81c14 505 SUPERFAMILY SSF52540 260 476 4.07E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS13950 300d55977e06abb2f80997b80fa81c14 505 SUPERFAMILY SSF52540 2 218 6.88E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS13950 300d55977e06abb2f80997b80fa81c14 505 ProSitePatterns PS00211 ABC transporters family signature. 388 402 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS13655 982b15be828eb00c277e79f6ca686c5d 341 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS13655 982b15be828eb00c277e79f6ca686c5d 341 Pfam PF00005 ABC transporter 28 171 2.9E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS13655 982b15be828eb00c277e79f6ca686c5d 341 SMART SM00382 37 219 2.4E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS13655 982b15be828eb00c277e79f6ca686c5d 341 SUPERFAMILY SSF52540 11 233 9.27E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS13655 982b15be828eb00c277e79f6ca686c5d 341 Gene3D G3DSA:3.40.50.300 7 252 2.6E-66 T 29-03-2018 SMALA_RS35045 7795a04088f28c209d9d92d2b464ac79 213 SUPERFAMILY SSF48498 79 193 1.95E-27 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS35045 7795a04088f28c209d9d92d2b464ac79 213 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 58 1.9E-13 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS35045 7795a04088f28c209d9d92d2b464ac79 213 SUPERFAMILY SSF46689 2 84 3.03E-18 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS35045 7795a04088f28c209d9d92d2b464ac79 213 Gene3D G3DSA:1.10.357.10 2 207 8.4E-33 T 29-03-2018 SMALA_RS35045 7795a04088f28c209d9d92d2b464ac79 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 3.8E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS35045 7795a04088f28c209d9d92d2b464ac79 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 3.8E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS39790 110af519ea621b497c79a65a45906350 349 SUPERFAMILY SSF50129 1 173 1.45E-50 T 29-03-2018 IPR011032 GroES-like SMALA_RS39790 110af519ea621b497c79a65a45906350 349 SUPERFAMILY SSF51735 141 311 8.02E-35 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS39790 110af519ea621b497c79a65a45906350 349 Gene3D G3DSA:3.40.50.720 157 317 2.2E-27 T 29-03-2018 SMALA_RS39790 110af519ea621b497c79a65a45906350 349 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 132 8.0E-30 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS39790 110af519ea621b497c79a65a45906350 349 SMART SM00829 7 342 0.0015 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS39790 110af519ea621b497c79a65a45906350 349 Gene3D G3DSA:3.90.180.10 1 156 1.8E-49 T 29-03-2018 SMALA_RS39790 110af519ea621b497c79a65a45906350 349 Pfam PF00107 Zinc-binding dehydrogenase 174 287 3.4E-19 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMALA_RS33910 bd29621dfbfd7635669d7f498ea07d4a 624 SUPERFAMILY SSF49899 361 617 6.8E-25 T 29-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain SMALA_RS33910 bd29621dfbfd7635669d7f498ea07d4a 624 Gene3D G3DSA:2.60.120.200 365 623 4.1E-30 T 29-03-2018 SMALA_RS33910 bd29621dfbfd7635669d7f498ea07d4a 624 Pfam PF00149 Calcineurin-like phosphoesterase 56 226 7.0E-7 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 SMALA_RS33910 bd29621dfbfd7635669d7f498ea07d4a 624 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 458 617 1.4E-15 T 29-03-2018 SMALA_RS33910 bd29621dfbfd7635669d7f498ea07d4a 624 SUPERFAMILY SSF56300 53 279 5.93E-21 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SMALA_RS33910 bd29621dfbfd7635669d7f498ea07d4a 624 Gene3D G3DSA:3.60.21.10 51 290 2.0E-19 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SMALA_RS02115 902cf96258762f172d50045002bd7fe9 141 Gene3D G3DSA:3.30.1330.40 12 141 4.2E-28 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SMALA_RS02115 902cf96258762f172d50045002bd7fe9 141 SUPERFAMILY SSF55298 21 136 2.36E-29 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SMALA_RS02115 902cf96258762f172d50045002bd7fe9 141 Pfam PF01042 Endoribonuclease L-PSP 21 134 9.8E-20 T 29-03-2018 IPR006175 YjgF/YER057c/UK114 family SMALA_RS20755 f36fcf291122b6faf9bfb62bb94e489c 549 Gene3D G3DSA:1.20.1250.20 24 215 5.4E-37 T 29-03-2018 SMALA_RS20755 f36fcf291122b6faf9bfb62bb94e489c 549 PRINTS PR01036 Tetracycline resistance protein TetB signature 152 176 1.9E-5 T 29-03-2018 SMALA_RS20755 f36fcf291122b6faf9bfb62bb94e489c 549 PRINTS PR01036 Tetracycline resistance protein TetB signature 316 340 1.9E-5 T 29-03-2018 SMALA_RS20755 f36fcf291122b6faf9bfb62bb94e489c 549 PRINTS PR01036 Tetracycline resistance protein TetB signature 122 142 1.9E-5 T 29-03-2018 SMALA_RS20755 f36fcf291122b6faf9bfb62bb94e489c 549 PRINTS PR01036 Tetracycline resistance protein TetB signature 31 55 1.9E-5 T 29-03-2018 SMALA_RS20755 f36fcf291122b6faf9bfb62bb94e489c 549 SUPERFAMILY SSF103473 262 470 7.85E-67 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS20755 f36fcf291122b6faf9bfb62bb94e489c 549 SUPERFAMILY SSF103473 17 211 7.85E-67 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS20755 f36fcf291122b6faf9bfb62bb94e489c 549 Gene3D G3DSA:1.20.1250.20 266 478 1.5E-19 T 29-03-2018 SMALA_RS20755 f36fcf291122b6faf9bfb62bb94e489c 549 Pfam PF07690 Major Facilitator Superfamily 33 424 2.7E-54 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS20755 f36fcf291122b6faf9bfb62bb94e489c 549 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 28 425 1.1E-78 T 29-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 SMALA_RS05535 e0773c08d358479c35e0a7d7db47a343 441 SUPERFAMILY SSF103473 3 428 5.62E-74 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS05535 e0773c08d358479c35e0a7d7db47a343 441 Gene3D G3DSA:1.20.1250.20 1 211 2.4E-34 T 29-03-2018 SMALA_RS05535 e0773c08d358479c35e0a7d7db47a343 441 Gene3D G3DSA:1.20.1250.20 228 431 7.7E-18 T 29-03-2018 SMALA_RS05535 e0773c08d358479c35e0a7d7db47a343 441 Pfam PF07690 Major Facilitator Superfamily 17 345 1.3E-37 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS20675 d241b7a7df8402a71bb4721e997676f9 537 ProSitePatterns PS00217 Sugar transport proteins signature 2. 164 189 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMALA_RS20675 d241b7a7df8402a71bb4721e997676f9 537 Gene3D G3DSA:1.20.1250.20 39 275 8.7E-29 T 29-03-2018 SMALA_RS20675 d241b7a7df8402a71bb4721e997676f9 537 Gene3D G3DSA:1.20.1250.20 276 512 3.1E-29 T 29-03-2018 SMALA_RS20675 d241b7a7df8402a71bb4721e997676f9 537 ProSitePatterns PS00216 Sugar transport proteins signature 1. 354 371 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMALA_RS20675 d241b7a7df8402a71bb4721e997676f9 537 SUPERFAMILY SSF103473 52 486 6.93E-73 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS20675 d241b7a7df8402a71bb4721e997676f9 537 Pfam PF00083 Sugar (and other) transporter 57 487 4.5E-53 T 29-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 SMALA_RS01885 252c2c9304e5261756e58d4f0f8e454e 216 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 35 49 2.4E-6 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS01885 252c2c9304e5261756e58d4f0f8e454e 216 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 49 65 2.4E-6 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS01885 252c2c9304e5261756e58d4f0f8e454e 216 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 75 1.3E-17 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS01885 252c2c9304e5261756e58d4f0f8e454e 216 Gene3D G3DSA:1.20.120.530 72 216 1.7E-31 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS01885 252c2c9304e5261756e58d4f0f8e454e 216 Gene3D G3DSA:1.10.10.10 1 71 1.5E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS01885 252c2c9304e5261756e58d4f0f8e454e 216 Pfam PF07729 FCD domain 86 208 1.1E-25 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS01885 252c2c9304e5261756e58d4f0f8e454e 216 SUPERFAMILY SSF48008 81 214 7.06E-28 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS01885 252c2c9304e5261756e58d4f0f8e454e 216 SMART SM00345 17 75 9.7E-15 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS01885 252c2c9304e5261756e58d4f0f8e454e 216 SUPERFAMILY SSF46785 13 79 3.97E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS01885 252c2c9304e5261756e58d4f0f8e454e 216 SMART SM00895 85 209 3.1E-18 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS35150 83c4fe21bc53956645051a0ffb28d8e0 435 Pfam PF00501 AMP-binding enzyme 94 291 7.9E-15 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS35150 83c4fe21bc53956645051a0ffb28d8e0 435 SUPERFAMILY SSF56801 24 427 1.02E-64 T 29-03-2018 SMALA_RS35150 83c4fe21bc53956645051a0ffb28d8e0 435 Gene3D G3DSA:3.30.300.30 329 434 2.1E-12 T 29-03-2018 SMALA_RS35150 83c4fe21bc53956645051a0ffb28d8e0 435 Pfam PF14535 AMP-binding enzyme C-terminal domain 339 432 1.1E-25 T 29-03-2018 IPR028154 AMP-dependent ligase, C-terminal SMALA_RS35150 83c4fe21bc53956645051a0ffb28d8e0 435 TIGRFAM TIGR02155 PA_CoA_ligase: phenylacetate-CoA ligase 14 432 8.2E-205 T 29-03-2018 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716 SMALA_RS35150 83c4fe21bc53956645051a0ffb28d8e0 435 Gene3D G3DSA:3.40.50.980 87 262 1.1E-22 T 29-03-2018 SMALA_RS35150 83c4fe21bc53956645051a0ffb28d8e0 435 PIRSF PIRSF006444 4 434 3.3E-200 T 29-03-2018 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716 SMALA_RS00705 d003ffc81159ec6098f45a002bdac8ac 391 SUPERFAMILY SSF111321 68 364 4.45E-44 T 29-03-2018 IPR002791 Domain of unknown function DUF89 SMALA_RS00705 d003ffc81159ec6098f45a002bdac8ac 391 Pfam PF01937 Protein of unknown function DUF89 23 369 2.3E-79 T 29-03-2018 IPR002791 Domain of unknown function DUF89 SMALA_RS01715 84a989c489a51636111b93afbb943007 340 Gene3D G3DSA:3.40.50.720 126 295 1.3E-56 T 29-03-2018 SMALA_RS01715 84a989c489a51636111b93afbb943007 340 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 233 249 - T 29-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site SMALA_RS01715 84a989c489a51636111b93afbb943007 340 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 120 294 6.5E-52 T 29-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 SMALA_RS01715 84a989c489a51636111b93afbb943007 340 SUPERFAMILY SSF51735 115 294 3.81E-54 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS01715 84a989c489a51636111b93afbb943007 340 Gene3D G3DSA:3.40.50.720 13 125 2.7E-15 T 29-03-2018 SMALA_RS16485 30be7123ab35a9c2dc397b952599f160 438 ProSitePatterns PS00216 Sugar transport proteins signature 1. 96 112 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMALA_RS16485 30be7123ab35a9c2dc397b952599f160 438 Gene3D G3DSA:1.20.1250.20 239 433 1.4E-15 T 29-03-2018 SMALA_RS16485 30be7123ab35a9c2dc397b952599f160 438 Gene3D G3DSA:1.20.1250.20 35 228 3.3E-29 T 29-03-2018 SMALA_RS16485 30be7123ab35a9c2dc397b952599f160 438 Pfam PF07690 Major Facilitator Superfamily 47 353 2.1E-34 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS16485 30be7123ab35a9c2dc397b952599f160 438 SUPERFAMILY SSF103473 28 424 8.89E-60 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS07480 3f8572f5d9137170fbe7e4f39600dee6 561 Pfam PF07508 Recombinase 194 320 1.0E-18 T 29-03-2018 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 SMALA_RS07480 3f8572f5d9137170fbe7e4f39600dee6 561 SMART SM00857 4 158 1.3E-4 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 SMALA_RS07480 3f8572f5d9137170fbe7e4f39600dee6 561 Pfam PF00239 Resolvase, N terminal domain 9 151 6.3E-7 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 SMALA_RS07480 3f8572f5d9137170fbe7e4f39600dee6 561 SUPERFAMILY SSF53041 9 149 5.23E-8 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 SMALA_RS07480 3f8572f5d9137170fbe7e4f39600dee6 561 Pfam PF13408 Recombinase zinc beta ribbon domain 341 392 3.1E-6 T 29-03-2018 IPR025827 Recombinase zinc beta ribbon domain SMALA_RS07480 3f8572f5d9137170fbe7e4f39600dee6 561 Gene3D G3DSA:3.40.50.1390 1 168 1.2E-16 T 29-03-2018 SMALA_RS03235 3382e056c0decb9912270d5814ea91bd 166 Pfam PF00355 Rieske [2Fe-2S] domain 74 152 2.8E-17 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMALA_RS03235 3382e056c0decb9912270d5814ea91bd 166 PRINTS PR00162 Rieske 2Fe-2S subunit signature 106 117 9.8E-7 T 29-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 SMALA_RS03235 3382e056c0decb9912270d5814ea91bd 166 PRINTS PR00162 Rieske 2Fe-2S subunit signature 126 138 9.8E-7 T 29-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 SMALA_RS03235 3382e056c0decb9912270d5814ea91bd 166 PRINTS PR00162 Rieske 2Fe-2S subunit signature 139 151 9.8E-7 T 29-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 SMALA_RS03235 3382e056c0decb9912270d5814ea91bd 166 SUPERFAMILY SSF50022 74 165 5.37E-27 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMALA_RS03235 3382e056c0decb9912270d5814ea91bd 166 Gene3D G3DSA:2.102.10.10 71 166 7.5E-23 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMALA_RS16840 a0417ed127dff966096f5b9c5e457673 329 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 157 322 5.3E-33 T 29-03-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 SMALA_RS16840 a0417ed127dff966096f5b9c5e457673 329 SUPERFAMILY SSF51735 5 156 3.72E-40 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS16840 a0417ed127dff966096f5b9c5e457673 329 PIRSF PIRSF000102 2 326 1.3E-57 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 SMALA_RS16840 a0417ed127dff966096f5b9c5e457673 329 TIGRFAM TIGR01759 MalateDH-SF1: malate dehydrogenase 4 323 7.4E-144 T 29-03-2018 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 SMALA_RS16840 a0417ed127dff966096f5b9c5e457673 329 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 7 147 1.9E-30 T 29-03-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 SMALA_RS16840 a0417ed127dff966096f5b9c5e457673 329 Hamap MF_01517 Malate dehydrogenase [mdh]. 2 327 56.942 T 29-03-2018 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 SMALA_RS16840 a0417ed127dff966096f5b9c5e457673 329 ProSitePatterns PS00068 Malate dehydrogenase active site signature. 156 168 - T 29-03-2018 IPR001252 Malate dehydrogenase, active site GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383|Reactome: R-HSA-70263 SMALA_RS16840 a0417ed127dff966096f5b9c5e457673 329 Gene3D G3DSA:3.40.50.720 7 156 2.3E-24 T 29-03-2018 SMALA_RS16840 a0417ed127dff966096f5b9c5e457673 329 Gene3D G3DSA:3.90.110.10 157 325 7.1E-54 T 29-03-2018 SMALA_RS16840 a0417ed127dff966096f5b9c5e457673 329 SUPERFAMILY SSF56327 157 324 1.85E-58 T 29-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 SMALA_RS22145 7976073b875f861b8d68fa8a3dd03077 214 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 106 117 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site SMALA_RS22145 7976073b875f861b8d68fa8a3dd03077 214 Gene3D G3DSA:3.30.70.20 51 108 6.8E-17 T 29-03-2018 SMALA_RS22145 7976073b875f861b8d68fa8a3dd03077 214 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 61 72 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site SMALA_RS22145 7976073b875f861b8d68fa8a3dd03077 214 Gene3D G3DSA:3.30.70.20 109 210 2.1E-7 T 29-03-2018 SMALA_RS22145 7976073b875f861b8d68fa8a3dd03077 214 TIGRFAM TIGR01971 NuoI: NADH-quinone oxidoreductase, chain I 17 144 1.7E-44 T 29-03-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS22145 7976073b875f861b8d68fa8a3dd03077 214 SUPERFAMILY SSF54862 34 151 3.1E-28 T 29-03-2018 SMALA_RS22145 7976073b875f861b8d68fa8a3dd03077 214 Hamap MF_01351 NAD(P)H-quinone oxidoreductase subunit I, chloroplastic [ndhI]. 8 150 28.612 T 29-03-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS22145 7976073b875f861b8d68fa8a3dd03077 214 Pfam PF12838 4Fe-4S dicluster domain 60 120 8.7E-12 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain SMALA_RS01030 a0d341a063b4b6dcd8e6497f7b72321d 235 Pfam PF01738 Dienelactone hydrolase family 27 232 4.1E-54 T 29-03-2018 IPR002925 Dienelactone hydrolase GO:0016787 SMALA_RS01030 a0d341a063b4b6dcd8e6497f7b72321d 235 SUPERFAMILY SSF53474 14 234 1.27E-41 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS01030 a0d341a063b4b6dcd8e6497f7b72321d 235 Gene3D G3DSA:3.40.50.1820 10 232 2.9E-33 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS00330 23a3db741ae1606b5f88574dfa8504ef 339 Gene3D G3DSA:3.20.20.100 3 315 2.9E-88 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS00330 23a3db741ae1606b5f88574dfa8504ef 339 PRINTS PR00069 Aldo-keto reductase signature 41 65 3.1E-5 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMALA_RS00330 23a3db741ae1606b5f88574dfa8504ef 339 PRINTS PR00069 Aldo-keto reductase signature 105 123 3.1E-5 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMALA_RS00330 23a3db741ae1606b5f88574dfa8504ef 339 PRINTS PR00069 Aldo-keto reductase signature 136 153 3.1E-5 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMALA_RS00330 23a3db741ae1606b5f88574dfa8504ef 339 Pfam PF00248 Aldo/keto reductase family 16 313 5.2E-71 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS00330 23a3db741ae1606b5f88574dfa8504ef 339 SUPERFAMILY SSF51430 1 314 3.8E-96 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS17005 5e1f44c0796852648b399f9c7efa2e48 612 SUPERFAMILY SSF56112 8 269 7.72E-74 T 29-03-2018 IPR011009 Protein kinase-like domain SMALA_RS17005 5e1f44c0796852648b399f9c7efa2e48 612 SUPERFAMILY SSF56112 316 357 7.72E-74 T 29-03-2018 IPR011009 Protein kinase-like domain SMALA_RS17005 5e1f44c0796852648b399f9c7efa2e48 612 Pfam PF00069 Protein kinase domain 12 262 1.2E-47 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMALA_RS17005 5e1f44c0796852648b399f9c7efa2e48 612 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 135 147 - T 29-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMALA_RS17005 5e1f44c0796852648b399f9c7efa2e48 612 SMART SM00220 12 271 6.4E-62 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMALA_RS17005 5e1f44c0796852648b399f9c7efa2e48 612 Gene3D G3DSA:1.10.510.10 100 345 1.5E-50 T 29-03-2018 SMALA_RS17005 5e1f44c0796852648b399f9c7efa2e48 612 Gene3D G3DSA:3.30.200.20 7 99 9.6E-23 T 29-03-2018 SMALA_RS17005 5e1f44c0796852648b399f9c7efa2e48 612 Gene3D G3DSA:3.40.1000.10 469 611 3.2E-18 T 29-03-2018 SMALA_RS17005 5e1f44c0796852648b399f9c7efa2e48 612 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 18 41 - T 29-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 SMALA_RS12720 cc5fbae17bc9a71db4fca69d8330a3da 141 Pfam PF01475 Ferric uptake regulator family 11 126 4.0E-32 T 29-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 SMALA_RS12720 cc5fbae17bc9a71db4fca69d8330a3da 141 SUPERFAMILY SSF46785 11 130 4.99E-33 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS12720 cc5fbae17bc9a71db4fca69d8330a3da 141 Gene3D G3DSA:1.10.10.10 8 87 2.8E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS04230 4d33447606286ad224af185cb7f80483 401 SUPERFAMILY SSF89796 7 401 5.62E-131 T 29-03-2018 IPR023606 CoA-transferase family III domain SMALA_RS04230 4d33447606286ad224af185cb7f80483 401 Gene3D G3DSA:3.40.50.10540 4 401 8.6E-142 T 29-03-2018 IPR023606 CoA-transferase family III domain SMALA_RS04230 4d33447606286ad224af185cb7f80483 401 Pfam PF02515 CoA-transferase family III 10 377 5.0E-121 T 29-03-2018 IPR003673 CoA-transferase family III GO:0003824 SMALA_RS09920 d0978c493a85af7a0755dfce302fdd07 310 SMART SM00382 35 253 3.5E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS09920 d0978c493a85af7a0755dfce302fdd07 310 SUPERFAMILY SSF52540 10 225 1.68E-49 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS09920 d0978c493a85af7a0755dfce302fdd07 310 Pfam PF00005 ABC transporter 26 162 2.4E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS09920 d0978c493a85af7a0755dfce302fdd07 310 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS09920 d0978c493a85af7a0755dfce302fdd07 310 Gene3D G3DSA:3.40.50.300 7 261 3.5E-52 T 29-03-2018 SMALA_RS20705 e2dc58fe4c07034765654b6f995b38f7 133 SUPERFAMILY SSF88723 8 123 9.32E-8 T 29-03-2018 IPR029060 PIN domain-like SMALA_RS20705 e2dc58fe4c07034765654b6f995b38f7 133 Gene3D G3DSA:3.40.50.1010 3 133 4.9E-12 T 29-03-2018 IPR029060 PIN domain-like SMALA_RS02500 4bf5976273cddff965bd4110ab5365b3 494 Pfam PF07690 Major Facilitator Superfamily 25 418 4.9E-48 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS02500 4bf5976273cddff965bd4110ab5365b3 494 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 21 431 7.5E-70 T 29-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 SMALA_RS02500 4bf5976273cddff965bd4110ab5365b3 494 Gene3D G3DSA:1.20.1250.20 260 483 4.6E-24 T 29-03-2018 SMALA_RS02500 4bf5976273cddff965bd4110ab5365b3 494 SUPERFAMILY SSF103473 256 476 9.59E-62 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS02500 4bf5976273cddff965bd4110ab5365b3 494 SUPERFAMILY SSF103473 11 199 9.59E-62 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS02500 4bf5976273cddff965bd4110ab5365b3 494 Gene3D G3DSA:1.20.1250.20 16 205 8.9E-30 T 29-03-2018 SMALA_RS24740 fa286e090a5a10d469701ad8bad65c5b 179 Hamap MF_01676 Alkyl hydroperoxide reductase AhpD [ahpD]. 1 179 87.017 T 29-03-2018 IPR004674 Alkylhydroperoxidase AhpD GO:0006979|GO:0032843|GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SMALA_RS24740 fa286e090a5a10d469701ad8bad65c5b 179 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 112 160 9.6E-22 T 29-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SMALA_RS24740 fa286e090a5a10d469701ad8bad65c5b 179 Pfam PF02627 Carboxymuconolactone decarboxylase family 94 175 7.5E-17 T 29-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SMALA_RS24740 fa286e090a5a10d469701ad8bad65c5b 179 TIGRFAM TIGR00777 ahpD: alkylhydroperoxidase, AhpD family 3 177 1.4E-91 T 29-03-2018 IPR004674 Alkylhydroperoxidase AhpD GO:0006979|GO:0032843|GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SMALA_RS24740 fa286e090a5a10d469701ad8bad65c5b 179 Gene3D G3DSA:1.20.1290.10 1 178 5.2E-48 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 SMALA_RS24740 fa286e090a5a10d469701ad8bad65c5b 179 SUPERFAMILY SSF69118 3 171 2.09E-49 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 SMALA_RS39070 7c4196670c160a994304d0174bfeb603 332 Gene3D G3DSA:3.90.180.10 1 147 1.6E-35 T 29-03-2018 SMALA_RS39070 7c4196670c160a994304d0174bfeb603 332 Pfam PF00107 Zinc-binding dehydrogenase 157 290 2.3E-23 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMALA_RS39070 7c4196670c160a994304d0174bfeb603 332 SMART SM00829 15 330 6.5E-7 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS39070 7c4196670c160a994304d0174bfeb603 332 SUPERFAMILY SSF51735 122 296 1.91E-50 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS39070 7c4196670c160a994304d0174bfeb603 332 SUPERFAMILY SSF50129 2 141 2.92E-34 T 29-03-2018 IPR011032 GroES-like SMALA_RS39070 7c4196670c160a994304d0174bfeb603 332 Pfam PF16884 N-terminal domain of oxidoreductase 6 110 5.8E-35 T 29-03-2018 SMALA_RS39070 7c4196670c160a994304d0174bfeb603 332 Gene3D G3DSA:3.40.50.720 148 273 1.1E-28 T 29-03-2018 SMALA_RS00955 c21c3d4726a591445cf36ac243d69f55 208 SUPERFAMILY SSF47741 106 192 1.7E-26 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 SMALA_RS00955 c21c3d4726a591445cf36ac243d69f55 208 SUPERFAMILY SSF54292 21 97 4.33E-25 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SMALA_RS00955 c21c3d4726a591445cf36ac243d69f55 208 Gene3D G3DSA:1.10.150.120 94 201 1.4E-32 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 SMALA_RS00955 c21c3d4726a591445cf36ac243d69f55 208 Gene3D G3DSA:3.10.20.30 17 93 2.8E-26 T 29-03-2018 IPR012675 Beta-grasp domain SMALA_RS00955 c21c3d4726a591445cf36ac243d69f55 208 Pfam PF01799 [2Fe-2S] binding domain 92 186 2.6E-28 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 SMALA_RS00955 c21c3d4726a591445cf36ac243d69f55 208 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 26 76 1.6E-7 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SMALA_RS00955 c21c3d4726a591445cf36ac243d69f55 208 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 58 66 - T 29-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 SMALA_RS40470 b14e86f19aa060a8d32a9d0c7e53ccd5 56 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 52 13.519 T 29-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS40470 b14e86f19aa060a8d32a9d0c7e53ccd5 56 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 42 9.1E-13 T 29-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS40470 b14e86f19aa060a8d32a9d0c7e53ccd5 56 Pfam PF01783 Ribosomal L32p protein family 2 46 3.3E-14 T 29-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS40470 b14e86f19aa060a8d32a9d0c7e53ccd5 56 SUPERFAMILY SSF57829 1 39 1.34E-9 T 29-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 SMALA_RS16240 8e2218f91e81db5a4ee300a8e49377f5 123 Gene3D G3DSA:1.10.10.10 30 121 3.0E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS16240 8e2218f91e81db5a4ee300a8e49377f5 123 SUPERFAMILY SSF88659 45 86 7.72E-5 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS16240 8e2218f91e81db5a4ee300a8e49377f5 123 Pfam PF05331 Protein of unknown function (DUF742) 10 120 7.4E-34 T 29-03-2018 IPR007995 Protein of unknown function DUF742 SMALA_RS32055 0cbba96bb3be02c9d55d1ddbcd3d4913 357 SUPERFAMILY SSF56796 10 347 1.23E-57 T 29-03-2018 SMALA_RS32055 0cbba96bb3be02c9d55d1ddbcd3d4913 357 Pfam PF13685 Iron-containing alcohol dehydrogenase 16 270 3.9E-55 T 29-03-2018 IPR032837 Glycerol-1-phosphate dehydrogenase KEGG: 00564+1.1.1.261|KEGG: 00630+1.1.1.26|MetaCyc: PWY-6349|MetaCyc: PWY-7294|MetaCyc: PWY-7295 SMALA_RS32055 0cbba96bb3be02c9d55d1ddbcd3d4913 357 PIRSF PIRSF000112 2 354 6.1E-101 T 29-03-2018 SMALA_RS32055 0cbba96bb3be02c9d55d1ddbcd3d4913 357 Gene3D G3DSA:1.20.1090.10 160 355 8.8E-35 T 29-03-2018 SMALA_RS32055 0cbba96bb3be02c9d55d1ddbcd3d4913 357 Gene3D G3DSA:3.40.50.1970 7 159 2.6E-20 T 29-03-2018 SMALA_RS19795 0f3cf27cc12a95e05e9e999466e7fc59 240 Pfam PF17258 Family of unknown function (DUF5324) 1 228 5.6E-105 T 29-03-2018 IPR035214 Protein of unknown function DUF5324 SMALA_RS19795 0f3cf27cc12a95e05e9e999466e7fc59 240 ProDom PD190647 REGULATORY RESISTANCE TRANSCRIPTION TRANSCRIPTIONAL ANTIBIOTIC DNA-BINDING ACTIVATOR REGULATION ORF699 NOSIHEPTIDE 1 239 7.0E-56 T 29-03-2018 IPR035214 Protein of unknown function DUF5324 SMALA_RS14410 971bc4f9f914ffc5c606040a67064860 341 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 130 339 1.1E-16 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS14410 971bc4f9f914ffc5c606040a67064860 341 SUPERFAMILY SSF161098 97 326 1.44E-55 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS14410 971bc4f9f914ffc5c606040a67064860 341 Gene3D G3DSA:1.10.3720.10 53 341 2.7E-52 T 29-03-2018 SMALA_RS15655 28a27ab182d76ec56dfab314e1e3be99 398 Pfam PF06224 Winged helix DNA-binding domain 47 366 2.8E-65 T 29-03-2018 IPR009351 Protein of unknown function DUF1006 SMALA_RS31290 17ffd81ac37e3f62b0c94b657cadf7c8 476 Gene3D G3DSA:1.20.1250.20 21 214 1.7E-24 T 29-03-2018 SMALA_RS31290 17ffd81ac37e3f62b0c94b657cadf7c8 476 Pfam PF07690 Major Facilitator Superfamily 288 468 4.3E-13 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS31290 17ffd81ac37e3f62b0c94b657cadf7c8 476 Pfam PF07690 Major Facilitator Superfamily 32 263 6.3E-31 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS31290 17ffd81ac37e3f62b0c94b657cadf7c8 476 Gene3D G3DSA:1.20.1250.20 276 475 4.1E-20 T 29-03-2018 SMALA_RS31290 17ffd81ac37e3f62b0c94b657cadf7c8 476 SUPERFAMILY SSF103473 22 216 1.18E-50 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS31290 17ffd81ac37e3f62b0c94b657cadf7c8 476 SUPERFAMILY SSF103473 264 466 1.18E-50 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS04140 70051ca98d716b01b7063106b6abd453 223 SUPERFAMILY SSF51735 2 206 1.11E-25 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS04140 70051ca98d716b01b7063106b6abd453 223 Gene3D G3DSA:3.40.50.720 2 220 1.2E-10 T 29-03-2018 SMALA_RS04140 70051ca98d716b01b7063106b6abd453 223 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 114 1.8E-4 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 SMALA_RS08625 a970e430094f67a566103681aafc7819 569 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 253 307 - T 29-03-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMALA_RS08625 a970e430094f67a566103681aafc7819 569 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 32 476 4.6E-146 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMALA_RS08625 a970e430094f67a566103681aafc7819 569 Gene3D G3DSA:1.20.210.10 19 532 1.1E-194 T 29-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMALA_RS08625 a970e430094f67a566103681aafc7819 569 PRINTS PR01165 Cytochrome c oxidase subunit I signature 297 312 7.3E-100 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMALA_RS08625 a970e430094f67a566103681aafc7819 569 PRINTS PR01165 Cytochrome c oxidase subunit I signature 230 251 7.3E-100 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMALA_RS08625 a970e430094f67a566103681aafc7819 569 PRINTS PR01165 Cytochrome c oxidase subunit I signature 432 453 7.3E-100 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMALA_RS08625 a970e430094f67a566103681aafc7819 569 PRINTS PR01165 Cytochrome c oxidase subunit I signature 70 93 7.3E-100 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMALA_RS08625 a970e430094f67a566103681aafc7819 569 PRINTS PR01165 Cytochrome c oxidase subunit I signature 97 121 7.3E-100 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMALA_RS08625 a970e430094f67a566103681aafc7819 569 PRINTS PR01165 Cytochrome c oxidase subunit I signature 201 220 7.3E-100 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMALA_RS08625 a970e430094f67a566103681aafc7819 569 PRINTS PR01165 Cytochrome c oxidase subunit I signature 251 272 7.3E-100 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMALA_RS08625 a970e430094f67a566103681aafc7819 569 PRINTS PR01165 Cytochrome c oxidase subunit I signature 382 401 7.3E-100 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMALA_RS08625 a970e430094f67a566103681aafc7819 569 PRINTS PR01165 Cytochrome c oxidase subunit I signature 354 372 7.3E-100 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMALA_RS08625 a970e430094f67a566103681aafc7819 569 PRINTS PR01165 Cytochrome c oxidase subunit I signature 319 340 7.3E-100 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMALA_RS08625 a970e430094f67a566103681aafc7819 569 PRINTS PR01165 Cytochrome c oxidase subunit I signature 140 152 7.3E-100 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMALA_RS08625 a970e430094f67a566103681aafc7819 569 PRINTS PR01165 Cytochrome c oxidase subunit I signature 23 48 7.3E-100 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMALA_RS08625 a970e430094f67a566103681aafc7819 569 PRINTS PR01165 Cytochrome c oxidase subunit I signature 172 190 7.3E-100 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMALA_RS08625 a970e430094f67a566103681aafc7819 569 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 24 528 1.3E-210 T 29-03-2018 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005507|GO:0005886|GO:0006810|GO:0022900|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 SMALA_RS08625 a970e430094f67a566103681aafc7819 569 SUPERFAMILY SSF81442 21 531 4.45E-176 T 29-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMALA_RS08555 08eb6717ebc8ac338384bcc6d8e5710a 143 Pfam PF04472 Cell division protein SepF 57 128 1.1E-23 T 29-03-2018 IPR007561 Cell division protein SepF/SepF-related GO:0090529 SMALA_RS08555 08eb6717ebc8ac338384bcc6d8e5710a 143 Hamap MF_01197 Cell division protein SepF [sepF]. 1 136 18.943 T 29-03-2018 IPR023052 Cell division protein SepF GO:0090529 SMALA_RS01045 1761dae0c9b6fb8afa7e960d2350fdee 148 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 31 142 1.6E-37 T 29-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 SMALA_RS01045 1761dae0c9b6fb8afa7e960d2350fdee 148 Gene3D G3DSA:2.30.110.10 7 144 2.5E-42 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS01045 1761dae0c9b6fb8afa7e960d2350fdee 148 Pfam PF04075 F420H(2)-dependent quinone reductase 14 142 2.0E-52 T 29-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 SMALA_RS35850 06ae16e0b5889e6004d3c1aea7196c3a 332 Gene3D G3DSA:1.20.5.170 2 51 3.4E-21 T 29-03-2018 SMALA_RS35850 06ae16e0b5889e6004d3c1aea7196c3a 332 Pfam PF03308 ArgK protein 22 294 1.5E-110 T 29-03-2018 SMALA_RS35850 06ae16e0b5889e6004d3c1aea7196c3a 332 TIGRFAM TIGR00750 lao: LAO/AO transport system ATPase 17 323 3.0E-112 T 29-03-2018 IPR005129 SIMIBI class G3E GTPase, ArgK/MeaB GO:0003924|GO:0005525 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMALA_RS35850 06ae16e0b5889e6004d3c1aea7196c3a 332 Gene3D G3DSA:3.40.50.300 52 262 2.0E-36 T 29-03-2018 SMALA_RS35850 06ae16e0b5889e6004d3c1aea7196c3a 332 SUPERFAMILY SSF52540 4 326 3.73E-94 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS35850 06ae16e0b5889e6004d3c1aea7196c3a 332 Gene3D G3DSA:1.10.287.130 264 324 3.7E-25 T 29-03-2018 SMALA_RS40565 c301773d1afd0a7871e0cdf62fcf8f90 484 Pfam PF00171 Aldehyde dehydrogenase family 21 473 4.6E-127 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS40565 c301773d1afd0a7871e0cdf62fcf8f90 484 Gene3D G3DSA:3.40.605.10 2 269 1.7E-68 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS40565 c301773d1afd0a7871e0cdf62fcf8f90 484 SUPERFAMILY SSF53720 8 478 4.45E-128 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMALA_RS40565 c301773d1afd0a7871e0cdf62fcf8f90 484 Gene3D G3DSA:3.40.309.10 270 461 5.9E-58 T 29-03-2018 SMALA_RS35800 336a88397af76bbf04d299940a0d9288 295 Gene3D G3DSA:3.40.50.720 1 157 7.3E-27 T 29-03-2018 SMALA_RS35800 336a88397af76bbf04d299940a0d9288 295 SUPERFAMILY SSF51735 6 155 2.82E-30 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS35800 336a88397af76bbf04d299940a0d9288 295 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 6 155 7.7E-21 T 29-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 SMALA_RS35800 336a88397af76bbf04d299940a0d9288 295 Gene3D G3DSA:1.10.1040.10 160 290 1.0E-13 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMALA_RS35800 336a88397af76bbf04d299940a0d9288 295 PIRSF PIRSF000103 1 291 1.3E-36 T 29-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 SMALA_RS09505 9e9a5efa38378dcdcd23f4f84bfa1953 350 Gene3D G3DSA:3.20.20.140 2 349 3.9E-38 T 29-03-2018 SMALA_RS16195 163823786cfb48d7082cac9776de7da1 319 SUPERFAMILY SSF53067 3 123 1.04E-32 T 29-03-2018 SMALA_RS16195 163823786cfb48d7082cac9776de7da1 319 Gene3D G3DSA:3.30.420.40 1 118 1.5E-49 T 29-03-2018 SMALA_RS16195 163823786cfb48d7082cac9776de7da1 319 Pfam PF02541 Ppx/GppA phosphatase family 28 314 1.2E-54 T 29-03-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 SMALA_RS16195 163823786cfb48d7082cac9776de7da1 319 SUPERFAMILY SSF53067 134 318 5.18E-37 T 29-03-2018 SMALA_RS16195 163823786cfb48d7082cac9776de7da1 319 Gene3D G3DSA:3.30.420.150 119 318 1.7E-52 T 29-03-2018 SMALA_RS16280 15078ca671bbbdeefe116bd237f8d111 231 Pfam PF07510 Protein of unknown function (DUF1524) 80 214 4.3E-16 T 29-03-2018 IPR011089 Domain of unknown function DUF1524 SMALA_RS16020 c57e4eb461b750e362c6282ba4c9abf3 122 SUPERFAMILY SSF52091 14 120 1.08E-25 T 29-03-2018 IPR002645 STAS domain SMALA_RS16020 c57e4eb461b750e362c6282ba4c9abf3 122 Gene3D G3DSA:3.30.750.24 10 122 1.4E-23 T 29-03-2018 IPR002645 STAS domain SMALA_RS16020 c57e4eb461b750e362c6282ba4c9abf3 122 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 14 117 5.6E-26 T 29-03-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 SMALA_RS16020 c57e4eb461b750e362c6282ba4c9abf3 122 Pfam PF13466 STAS domain 30 106 6.7E-16 T 29-03-2018 IPR002645 STAS domain SMALA_RS10195 31e37d2c084aab7409c1ab4381947377 239 Gene3D G3DSA:3.20.20.10 1 239 2.6E-62 T 29-03-2018 IPR029066 PLP-binding barrel SMALA_RS10195 31e37d2c084aab7409c1ab4381947377 239 ProSitePatterns PS01211 Uncharacterized protein family UPF0001 signature. 80 94 - T 29-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein SMALA_RS10195 31e37d2c084aab7409c1ab4381947377 239 Pfam PF01168 Alanine racemase, N-terminal domain 29 236 5.8E-22 T 29-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SMALA_RS10195 31e37d2c084aab7409c1ab4381947377 239 PIRSF PIRSF004848 1 239 3.3E-65 T 29-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein SMALA_RS10195 31e37d2c084aab7409c1ab4381947377 239 SUPERFAMILY SSF51419 4 233 4.42E-60 T 29-03-2018 IPR029066 PLP-binding barrel SMALA_RS10195 31e37d2c084aab7409c1ab4381947377 239 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 9 235 1.0E-40 T 29-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein SMALA_RS31495 71c8025cc9f36fcd7c233b1c02a3beb8 103 SUPERFAMILY SSF54909 7 100 5.07E-25 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel SMALA_RS31495 71c8025cc9f36fcd7c233b1c02a3beb8 103 Gene3D G3DSA:3.30.70.100 1 103 1.1E-25 T 29-03-2018 SMALA_RS31495 71c8025cc9f36fcd7c233b1c02a3beb8 103 Pfam PF03992 Antibiotic biosynthesis monooxygenase 7 81 7.2E-17 T 29-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain SMALA_RS07030 20f7df41251967e6f98c2d33384c8cc8 333 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 53 324 1.5E-31 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SMALA_RS07030 20f7df41251967e6f98c2d33384c8cc8 333 Gene3D G3DSA:3.20.20.300 13 333 4.4E-42 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SMALA_RS07030 20f7df41251967e6f98c2d33384c8cc8 333 SUPERFAMILY SSF51445 58 329 7.58E-40 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS37525 c04ecc905045f226d773fa5016b32adb 421 SUPERFAMILY SSF55931 24 249 3.53E-38 T 29-03-2018 SMALA_RS37525 c04ecc905045f226d773fa5016b32adb 421 SUPERFAMILY SSF55931 285 412 3.53E-38 T 29-03-2018 SMALA_RS37525 c04ecc905045f226d773fa5016b32adb 421 Hamap MF_02034 Glutamate--cysteine ligase EgtA [egtA]. 7 407 31.794 T 29-03-2018 IPR017809 Glutamate--cysteine ligase EgtA, Actinobacteria GO:0004357|GO:0052699 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 SMALA_RS37525 c04ecc905045f226d773fa5016b32adb 421 TIGRFAM TIGR03444 EgtA_Cys_ligase: ergothioneine biosynthesis glutamate--cysteine ligase EgtA 20 409 1.8E-132 T 29-03-2018 IPR017809 Glutamate--cysteine ligase EgtA, Actinobacteria GO:0004357|GO:0052699 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 SMALA_RS37525 c04ecc905045f226d773fa5016b32adb 421 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 33 335 2.7E-75 T 29-03-2018 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 SMALA_RS37525 c04ecc905045f226d773fa5016b32adb 421 PIRSF PIRSF017901 3 421 5.9E-114 T 29-03-2018 IPR035434 Glutamate--cysteine ligase, bacteria and plant GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 SMALA_RS18590 814fa1fc7f697e52d0e3ca85c4124e10 412 SUPERFAMILY SSF53056 145 369 1.83E-49 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SMALA_RS18590 814fa1fc7f697e52d0e3ca85c4124e10 412 SMART SM00947 170 360 9.6E-55 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SMALA_RS18590 814fa1fc7f697e52d0e3ca85c4124e10 412 Gene3D G3DSA:3.40.1050.10 136 375 7.3E-69 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SMALA_RS18590 814fa1fc7f697e52d0e3ca85c4124e10 412 Pfam PF00484 Carbonic anhydrase 178 354 7.0E-43 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SMALA_RS13730 7b19277fce13342a9923fe562541ecb8 155 SUPERFAMILY SSF55811 6 141 7.58E-21 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMALA_RS13730 7b19277fce13342a9923fe562541ecb8 155 Pfam PF00293 NUDIX domain 10 136 2.7E-10 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SMALA_RS13730 7b19277fce13342a9923fe562541ecb8 155 Gene3D G3DSA:3.90.79.10 5 142 7.7E-20 T 29-03-2018 SMALA_RS13730 7b19277fce13342a9923fe562541ecb8 155 PRINTS PR00502 NUDIX hydrolase family signature 56 71 5.1E-5 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMALA_RS13730 7b19277fce13342a9923fe562541ecb8 155 PRINTS PR00502 NUDIX hydrolase family signature 33 47 5.1E-5 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMALA_RS21040 1f70bc317c7a261e00a104d2177440b7 536 Pfam PF00149 Calcineurin-like phosphoesterase 284 451 3.5E-14 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 SMALA_RS21040 1f70bc317c7a261e00a104d2177440b7 536 Gene3D G3DSA:3.60.21.10 279 497 1.3E-27 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SMALA_RS21040 1f70bc317c7a261e00a104d2177440b7 536 SUPERFAMILY SSF56300 280 482 6.55E-31 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SMALA_RS40030 aeab5476b8e40a30b23951c2726ea918 259 Pfam PF03746 LamB/YcsF family 4 240 3.8E-91 T 29-03-2018 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF SMALA_RS40030 aeab5476b8e40a30b23951c2726ea918 259 SUPERFAMILY SSF88713 4 252 3.89E-88 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 SMALA_RS40030 aeab5476b8e40a30b23951c2726ea918 259 Hamap MF_00691 UPF0271 protein YbgL [ybgL]. 2 245 42.015 T 29-03-2018 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF SMALA_RS40030 aeab5476b8e40a30b23951c2726ea918 259 Gene3D G3DSA:3.20.20.370 3 249 5.8E-94 T 29-03-2018 SMALA_RS38865 a9538029a4a7db152b999fddd4979857 309 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 216 3.2E-19 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 SMALA_RS38865 a9538029a4a7db152b999fddd4979857 309 Gene3D G3DSA:3.40.50.720 1 162 1.3E-22 T 29-03-2018 SMALA_RS38865 a9538029a4a7db152b999fddd4979857 309 SUPERFAMILY SSF51735 1 284 9.14E-48 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS38865 a9538029a4a7db152b999fddd4979857 309 Gene3D G3DSA:3.90.25.10 163 297 8.3E-21 T 29-03-2018 SMALA_RS10535 c8f0931d564930634f082247ec38d638 206 SUPERFAMILY SSF81452 13 204 2.22E-54 T 29-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMALA_RS10535 c8f0931d564930634f082247ec38d638 206 Gene3D G3DSA:1.20.120.80 20 206 1.0E-55 T 29-03-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMALA_RS10535 c8f0931d564930634f082247ec38d638 206 Pfam PF00510 Cytochrome c oxidase subunit III 26 204 1.7E-24 T 29-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMALA_RS35670 9be93e56821382ffe752d0c180719fa0 699 Gene3D G3DSA:3.40.50.1820 206 627 4.3E-4 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS35670 9be93e56821382ffe752d0c180719fa0 699 SUPERFAMILY SSF53474 558 602 3.05E-5 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS35670 9be93e56821382ffe752d0c180719fa0 699 SUPERFAMILY SSF53474 289 332 3.05E-5 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS35670 9be93e56821382ffe752d0c180719fa0 699 Pfam PF10605 3HB-oligomer hydrolase (3HBOH) 31 699 6.9E-196 T 29-03-2018 IPR016582 D-(-)-3-hydroxybutyrate oligomer hydrolase, putative GO:0005615|GO:0019605|GO:0047989 KEGG: 00650+3.1.1.22 SMALA_RS00830 c00e9edd6666bd6a0c1b61edbe867e76 357 Gene3D G3DSA:3.40.190.10 36 295 5.4E-4 T 29-03-2018 SMALA_RS23715 34a2fd351c072519636a16f462bfbb04 155 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 86 94 4.8E-5 T 29-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 SMALA_RS23715 34a2fd351c072519636a16f462bfbb04 155 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 96 105 4.8E-5 T 29-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 SMALA_RS23715 34a2fd351c072519636a16f462bfbb04 155 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 3 17 4.8E-5 T 29-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 SMALA_RS23715 34a2fd351c072519636a16f462bfbb04 155 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 1 138 7.5E-34 T 29-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 SMALA_RS23715 34a2fd351c072519636a16f462bfbb04 155 ProSitePatterns PS01327 Large-conductance mechanosensitive channels mscL family signature. 10 23 - T 29-03-2018 IPR019823 Large-conductance mechanosensitive channel, conserved site SMALA_RS23715 34a2fd351c072519636a16f462bfbb04 155 SUPERFAMILY SSF81330 9 120 7.85E-24 T 29-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 SMALA_RS23715 34a2fd351c072519636a16f462bfbb04 155 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 3 139 3.1E-22 T 29-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 SMALA_RS39005 70ac583bfca41a394d972424bdd388f3 369 SUPERFAMILY SSF51604 119 359 1.23E-62 T 29-03-2018 IPR029065 Enolase C-terminal domain-like SMALA_RS39005 70ac583bfca41a394d972424bdd388f3 369 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 8 119 1.0E-16 T 29-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain SMALA_RS39005 70ac583bfca41a394d972424bdd388f3 369 Gene3D G3DSA:3.20.20.120 126 366 9.3E-57 T 29-03-2018 IPR029065 Enolase C-terminal domain-like SMALA_RS39005 70ac583bfca41a394d972424bdd388f3 369 Pfam PF13378 Enolase C-terminal domain-like 143 352 5.1E-52 T 29-03-2018 IPR029065 Enolase C-terminal domain-like SMALA_RS39005 70ac583bfca41a394d972424bdd388f3 369 SMART SM00922 140 234 4.0E-27 T 29-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal SMALA_RS39005 70ac583bfca41a394d972424bdd388f3 369 Gene3D G3DSA:3.30.390.10 1 125 2.3E-37 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMALA_RS39005 70ac583bfca41a394d972424bdd388f3 369 SUPERFAMILY SSF54826 1 119 2.25E-28 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMALA_RS34230 97458b868d9d3d00361b5a28db9eaaad 316 SUPERFAMILY SSF161098 72 296 1.13E-58 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS34230 97458b868d9d3d00361b5a28db9eaaad 316 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 103 311 3.0E-23 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS34230 97458b868d9d3d00361b5a28db9eaaad 316 Gene3D G3DSA:1.20.58.370 17 61 4.0E-4 T 29-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain SMALA_RS34230 97458b868d9d3d00361b5a28db9eaaad 316 Gene3D G3DSA:1.10.3720.10 79 307 5.8E-47 T 29-03-2018 SMALA_RS27775 47293dcec631d6d07d4a6c4e23b5ffe8 419 Gene3D G3DSA:1.10.10.60 344 389 6.9E-9 T 29-03-2018 SMALA_RS27775 47293dcec631d6d07d4a6c4e23b5ffe8 419 Pfam PF13556 PucR C-terminal helix-turn-helix domain 353 411 8.1E-20 T 29-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain SMALA_RS23200 858fa9bcec8f9e0fe017b93f252e4e2a 375 Pfam PF00296 Luciferase-like monooxygenase 1 329 5.1E-43 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS23200 858fa9bcec8f9e0fe017b93f252e4e2a 375 Gene3D G3DSA:3.20.20.30 1 374 4.5E-65 T 29-03-2018 SMALA_RS23200 858fa9bcec8f9e0fe017b93f252e4e2a 375 SUPERFAMILY SSF51679 1 358 2.88E-65 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS15390 a66c06ed4e2b3c6898e99f4c209cf788 173 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 38 70 - T 29-03-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS15390 a66c06ed4e2b3c6898e99f4c209cf788 173 Pfam PF04542 Sigma-70 region 2 15 83 1.6E-16 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS15390 a66c06ed4e2b3c6898e99f4c209cf788 173 Pfam PF04545 Sigma-70, region 4 115 163 8.5E-13 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS15390 a66c06ed4e2b3c6898e99f4c209cf788 173 SUPERFAMILY SSF88659 102 166 1.27E-12 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS15390 a66c06ed4e2b3c6898e99f4c209cf788 173 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 12 164 3.7E-24 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS15390 a66c06ed4e2b3c6898e99f4c209cf788 173 Gene3D G3DSA:1.10.10.10 82 169 1.7E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS15390 a66c06ed4e2b3c6898e99f4c209cf788 173 Gene3D G3DSA:1.10.1740.10 2 81 3.8E-21 T 29-03-2018 SMALA_RS15390 a66c06ed4e2b3c6898e99f4c209cf788 173 SUPERFAMILY SSF88946 8 96 9.81E-21 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS10955 2ab00e20e2a569386dbaf4ea9edc29e4 261 SUPERFAMILY SSF53474 9 258 3.68E-51 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS10955 2ab00e20e2a569386dbaf4ea9edc29e4 261 Pfam PF00561 alpha/beta hydrolase fold 20 245 1.0E-20 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS10955 2ab00e20e2a569386dbaf4ea9edc29e4 261 Gene3D G3DSA:3.40.50.1820 1 261 4.8E-42 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS10955 2ab00e20e2a569386dbaf4ea9edc29e4 261 PRINTS PR00111 Alpha/beta hydrolase fold signature 44 59 2.2E-8 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS10955 2ab00e20e2a569386dbaf4ea9edc29e4 261 PRINTS PR00111 Alpha/beta hydrolase fold signature 88 101 2.2E-8 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS10955 2ab00e20e2a569386dbaf4ea9edc29e4 261 PRINTS PR00111 Alpha/beta hydrolase fold signature 102 115 2.2E-8 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS00560 0cb9c09e4ff83156cf5255e06ddf3b7b 273 SUPERFAMILY SSF55718 175 257 2.24E-8 T 29-03-2018 IPR003033 SCP2 sterol-binding domain SMALA_RS00560 0cb9c09e4ff83156cf5255e06ddf3b7b 273 Gene3D G3DSA:3.30.1050.10 163 272 1.1E-7 T 29-03-2018 IPR003033 SCP2 sterol-binding domain SMALA_RS00560 0cb9c09e4ff83156cf5255e06ddf3b7b 273 SUPERFAMILY SSF109854 20 159 2.29E-10 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes SMALA_RS00560 0cb9c09e4ff83156cf5255e06ddf3b7b 273 Gene3D G3DSA:1.20.120.450 15 159 2.4E-11 T 29-03-2018 SMALA_RS00560 0cb9c09e4ff83156cf5255e06ddf3b7b 273 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 22 241 4.1E-20 T 29-03-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type SMALA_RS00560 0cb9c09e4ff83156cf5255e06ddf3b7b 273 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 25 152 2.2E-5 T 29-03-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 SMALA_RS06115 976ff6ae9b44a7a6eccfddaa16ab97e6 179 Gene3D G3DSA:1.10.10.60 1 16 0.0012 T 29-03-2018 SMALA_RS06115 976ff6ae9b44a7a6eccfddaa16ab97e6 179 Gene3D G3DSA:1.10.357.10 17 172 1.8E-18 T 29-03-2018 SMALA_RS06115 976ff6ae9b44a7a6eccfddaa16ab97e6 179 Pfam PF00440 Bacterial regulatory proteins, tetR family 3 31 1.1E-4 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS06115 976ff6ae9b44a7a6eccfddaa16ab97e6 179 SUPERFAMILY SSF46689 3 43 1.85E-7 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS10055 4299af54942d6858923018d9cbb295ef 243 Gene3D G3DSA:3.20.20.70 6 243 6.4E-53 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS10055 4299af54942d6858923018d9cbb295ef 243 Pfam PF00977 Histidine biosynthesis protein 8 233 1.3E-62 T 29-03-2018 IPR006062 Histidine biosynthesis GO:0000105 SMALA_RS10055 4299af54942d6858923018d9cbb295ef 243 TIGRFAM TIGR01919 hisA-trpF: bifunctional HisA/TrpF protein 6 241 3.6E-118 T 29-03-2018 IPR010188 Bifunctional HisA/TrpF GO:0000105|GO:0000162|GO:0003949|GO:0004640|GO:0005737 KEGG: 00340+5.3.1.16 SMALA_RS10055 4299af54942d6858923018d9cbb295ef 243 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 7 240 31.527 T 29-03-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 SMALA_RS10055 4299af54942d6858923018d9cbb295ef 243 SUPERFAMILY SSF51366 6 239 2.04E-63 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 SMALA_RS06500 fd14f741010ccb0e77313b2bf5336199 406 Pfam PF00149 Calcineurin-like phosphoesterase 173 341 2.8E-8 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 SMALA_RS06500 fd14f741010ccb0e77313b2bf5336199 406 Gene3D G3DSA:3.60.21.10 170 387 5.7E-24 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SMALA_RS06500 fd14f741010ccb0e77313b2bf5336199 406 SUPERFAMILY SSF56300 168 400 1.61E-35 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SMALA_RS18070 faca38bb191e15534a79f05fa26d628c 385 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 14 364 1.7E-104 T 29-03-2018 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 SMALA_RS18070 faca38bb191e15534a79f05fa26d628c 385 SUPERFAMILY SSF52540 1 239 3.08E-76 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS18070 faca38bb191e15534a79f05fa26d628c 385 Gene3D G3DSA:3.10.580.10 302 367 5.4E-5 T 29-03-2018 SMALA_RS18070 faca38bb191e15534a79f05fa26d628c 385 SUPERFAMILY SSF54631 258 364 8.01E-12 T 29-03-2018 SMALA_RS18070 faca38bb191e15534a79f05fa26d628c 385 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS18070 faca38bb191e15534a79f05fa26d628c 385 Gene3D G3DSA:3.10.580.10 241 301 0.0084 T 29-03-2018 SMALA_RS18070 faca38bb191e15534a79f05fa26d628c 385 Pfam PF00005 ABC transporter 19 164 2.0E-34 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS18070 faca38bb191e15534a79f05fa26d628c 385 Gene3D G3DSA:3.40.50.300 1 240 2.8E-73 T 29-03-2018 SMALA_RS18070 faca38bb191e15534a79f05fa26d628c 385 SMART SM00382 27 222 2.1E-19 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS01100 8a84e8be72a6b545bcc1da2c4819cb88 529 Pfam PF00474 Sodium:solute symporter family 38 453 1.4E-40 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 SMALA_RS17660 44ee2242459d542c0da54ee42ad4c428 316 SUPERFAMILY SSF55315 70 148 1.41E-14 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like SMALA_RS17660 44ee2242459d542c0da54ee42ad4c428 316 SUPERFAMILY SSF75217 139 315 6.54E-42 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases SMALA_RS17660 44ee2242459d542c0da54ee42ad4c428 316 Gene3D G3DSA:3.40.1280.10 150 316 7.3E-42 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal SMALA_RS17660 44ee2242459d542c0da54ee42ad4c428 316 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 73 315 9.7E-58 T 29-03-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 SMALA_RS17660 44ee2242459d542c0da54ee42ad4c428 316 SMART SM00967 74 151 3.7E-20 T 29-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 SMALA_RS17660 44ee2242459d542c0da54ee42ad4c428 316 Pfam PF00588 SpoU rRNA Methylase family 168 309 6.0E-32 T 29-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 SMALA_RS17660 44ee2242459d542c0da54ee42ad4c428 316 Gene3D G3DSA:3.30.1330.30 65 147 7.9E-15 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like SMALA_RS17660 44ee2242459d542c0da54ee42ad4c428 316 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 75 151 2.0E-19 T 29-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 SMALA_RS10485 0124c32bb0dd7e6770f7ba0c95f9b46a 341 Gene3D G3DSA:1.20.120.330 19 221 4.5E-9 T 29-03-2018 SMALA_RS10485 0124c32bb0dd7e6770f7ba0c95f9b46a 341 Gene3D G3DSA:3.90.1720.10 222 336 6.5E-36 T 29-03-2018 SMALA_RS10485 0124c32bb0dd7e6770f7ba0c95f9b46a 341 SUPERFAMILY SSF54001 225 332 2.75E-38 T 29-03-2018 SMALA_RS10485 0124c32bb0dd7e6770f7ba0c95f9b46a 341 Pfam PF00877 NlpC/P60 family 242 336 3.1E-24 T 29-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain SMALA_RS39205 9c8dfd37ab4f85dc2baac29c914abe86 328 Gene3D G3DSA:3.40.50.150 106 328 5.4E-31 T 29-03-2018 SMALA_RS39205 9c8dfd37ab4f85dc2baac29c914abe86 328 Pfam PF08242 Methyltransferase domain 156 259 1.7E-10 T 29-03-2018 IPR013217 Methyltransferase type 12 SMALA_RS39205 9c8dfd37ab4f85dc2baac29c914abe86 328 Gene3D G3DSA:1.10.10.10 2 105 5.0E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS39205 9c8dfd37ab4f85dc2baac29c914abe86 328 SUPERFAMILY SSF53335 137 317 2.17E-31 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS42120 ff347853dfcdba7cc1b91147f734062b 312 SMART SM01130 11 304 8.7E-38 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SMALA_RS42120 ff347853dfcdba7cc1b91147f734062b 312 Pfam PF00701 Dihydrodipicolinate synthetase family 12 291 6.8E-26 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SMALA_RS42120 ff347853dfcdba7cc1b91147f734062b 312 PIRSF PIRSF001365 9 310 7.9E-34 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SMALA_RS42120 ff347853dfcdba7cc1b91147f734062b 312 SUPERFAMILY SSF51569 12 301 2.41E-45 T 29-03-2018 SMALA_RS42120 ff347853dfcdba7cc1b91147f734062b 312 Gene3D G3DSA:3.20.20.70 1 312 3.4E-51 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS17040 f128a70b0544d71b8b4cc59cc19fca82 213 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 174 209 3.1E-4 T 29-03-2018 SMALA_RS38805 9a7b50ed5822cafdf82d3a5ddc2af860 302 PRINTS PR00474 Glutamate 5-kinase family signature 205 225 9.0E-6 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 SMALA_RS38805 9a7b50ed5822cafdf82d3a5ddc2af860 302 PRINTS PR00474 Glutamate 5-kinase family signature 153 180 9.0E-6 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 SMALA_RS38805 9a7b50ed5822cafdf82d3a5ddc2af860 302 PRINTS PR00474 Glutamate 5-kinase family signature 33 47 9.0E-6 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 SMALA_RS38805 9a7b50ed5822cafdf82d3a5ddc2af860 302 SUPERFAMILY SSF53633 4 244 5.11E-64 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase SMALA_RS38805 9a7b50ed5822cafdf82d3a5ddc2af860 302 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 63 250 4.3E-65 T 29-03-2018 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 SMALA_RS38805 9a7b50ed5822cafdf82d3a5ddc2af860 302 Gene3D G3DSA:3.40.1160.10 1 244 2.1E-68 T 29-03-2018 SMALA_RS38805 9a7b50ed5822cafdf82d3a5ddc2af860 302 Pfam PF00696 Amino acid kinase family 3 231 4.8E-47 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase SMALA_RS38805 9a7b50ed5822cafdf82d3a5ddc2af860 302 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 29-03-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 SMALA_RS30155 a073ebca0eb043b46ed707880e87b520 240 Gene3D G3DSA:3.30.420.10 7 199 6.4E-34 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SMALA_RS30155 a073ebca0eb043b46ed707880e87b520 240 Pfam PF00929 Exonuclease 10 178 5.8E-18 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III SMALA_RS30155 a073ebca0eb043b46ed707880e87b520 240 SUPERFAMILY SSF53098 6 202 7.59E-47 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SMALA_RS30155 a073ebca0eb043b46ed707880e87b520 240 SMART SM00479 7 188 1.6E-18 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III SMALA_RS27095 270f65240a19dfc1d3336b2a4ff7dd60 114 TIGRFAM TIGR03954 integ_memb_HG: integral membrane protein 13 94 1.9E-23 T 29-03-2018 IPR023845 Domain of unknown function DUF3817, transmembrane SMALA_RS27095 270f65240a19dfc1d3336b2a4ff7dd60 114 Pfam PF12823 Domain of unknown function (DUF3817) 9 95 6.9E-23 T 29-03-2018 IPR023845 Domain of unknown function DUF3817, transmembrane SMALA_RS05815 52d3fb76b439b789e904e3a118298f9e 311 SUPERFAMILY SSF53850 87 287 7.06E-31 T 29-03-2018 SMALA_RS05815 52d3fb76b439b789e904e3a118298f9e 311 Gene3D G3DSA:1.10.10.10 1 83 1.0E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS05815 52d3fb76b439b789e904e3a118298f9e 311 SUPERFAMILY SSF46785 1 84 2.56E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS05815 52d3fb76b439b789e904e3a118298f9e 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.3E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS05815 52d3fb76b439b789e904e3a118298f9e 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.3E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS05815 52d3fb76b439b789e904e3a118298f9e 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.3E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS05815 52d3fb76b439b789e904e3a118298f9e 311 Gene3D G3DSA:3.40.190.10 88 179 1.7E-18 T 29-03-2018 SMALA_RS05815 52d3fb76b439b789e904e3a118298f9e 311 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 3.6E-20 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS05815 52d3fb76b439b789e904e3a118298f9e 311 Gene3D G3DSA:3.40.190.10 180 263 8.8E-20 T 29-03-2018 SMALA_RS05815 52d3fb76b439b789e904e3a118298f9e 311 Pfam PF03466 LysR substrate binding domain 87 286 6.1E-34 T 29-03-2018 IPR005119 LysR, substrate-binding SMALA_RS05435 07103dcc3a3bb6a573106104e44236a8 391 Pfam PF04542 Sigma-70 region 2 5 68 2.4E-9 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS05435 07103dcc3a3bb6a573106104e44236a8 391 SUPERFAMILY SSF88659 91 149 2.05E-8 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS05435 07103dcc3a3bb6a573106104e44236a8 391 Gene3D G3DSA:1.10.1740.10 2 68 1.3E-15 T 29-03-2018 SMALA_RS05435 07103dcc3a3bb6a573106104e44236a8 391 SUPERFAMILY SSF88946 3 84 1.61E-12 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS05435 07103dcc3a3bb6a573106104e44236a8 391 Gene3D G3DSA:1.25.40.10 209 377 1.6E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS05435 07103dcc3a3bb6a573106104e44236a8 391 Gene3D G3DSA:1.10.10.10 69 151 1.8E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS05435 07103dcc3a3bb6a573106104e44236a8 391 Pfam PF08281 Sigma-70, region 4 98 148 1.3E-7 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS09305 9af8299cd17c1721990b5ac8210fe967 285 Gene3D G3DSA:3.20.20.370 61 278 3.0E-53 T 29-03-2018 SMALA_RS09305 9af8299cd17c1721990b5ac8210fe967 285 SUPERFAMILY SSF88713 89 273 8.9E-60 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 SMALA_RS09305 9af8299cd17c1721990b5ac8210fe967 285 Pfam PF01522 Polysaccharide deacetylase 89 206 6.3E-39 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 SMALA_RS41715 1cfd8387ac3d730e68d09d0c28b1e939 385 Gene3D G3DSA:3.40.190.10 62 176 1.8E-14 T 29-03-2018 SMALA_RS41715 1cfd8387ac3d730e68d09d0c28b1e939 385 Pfam PF13343 Bacterial extracellular solute-binding protein 117 340 7.1E-34 T 29-03-2018 SMALA_RS41715 1cfd8387ac3d730e68d09d0c28b1e939 385 SUPERFAMILY SSF53850 71 350 3.54E-51 T 29-03-2018 SMALA_RS41715 1cfd8387ac3d730e68d09d0c28b1e939 385 Gene3D G3DSA:3.40.190.10 177 384 2.3E-27 T 29-03-2018 SMALA_RS33430 ba124271d5784db4c58145a161b8ea8a 89 SUPERFAMILY SSF47336 10 83 5.5E-17 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS33430 ba124271d5784db4c58145a161b8ea8a 89 ProSitePatterns PS00012 Phosphopantetheine attachment site. 40 55 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS33430 ba124271d5784db4c58145a161b8ea8a 89 SMART SM00823 Phosphopantetheine attachment site 14 85 2.8E-12 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS33430 ba124271d5784db4c58145a161b8ea8a 89 SMART SM01294 15 81 4.5E-6 T 29-03-2018 SMALA_RS33430 ba124271d5784db4c58145a161b8ea8a 89 Gene3D G3DSA:1.10.1200.10 2 85 5.4E-18 T 29-03-2018 SMALA_RS33430 ba124271d5784db4c58145a161b8ea8a 89 Pfam PF00550 Phosphopantetheine attachment site 15 80 2.8E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS28005 babe04b7443caf69040382f3094b6496 358 Gene3D G3DSA:1.20.5.620 46 119 2.7E-9 T 29-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain SMALA_RS31275 8745a74b81c45fd2c59a2ba68fec7b34 120 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS31275 8745a74b81c45fd2c59a2ba68fec7b34 120 SUPERFAMILY SSF46955 1 113 3.3E-26 T 29-03-2018 IPR009061 Putative DNA-binding domain SMALA_RS31275 8745a74b81c45fd2c59a2ba68fec7b34 120 SMART SM00422 1 69 2.2E-21 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS31275 8745a74b81c45fd2c59a2ba68fec7b34 120 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 4.5E-8 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS31275 8745a74b81c45fd2c59a2ba68fec7b34 120 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 4.5E-8 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS31275 8745a74b81c45fd2c59a2ba68fec7b34 120 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 4.5E-8 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS31275 8745a74b81c45fd2c59a2ba68fec7b34 120 Gene3D G3DSA:1.10.1660.10 55 120 5.0E-11 T 29-03-2018 SMALA_RS31275 8745a74b81c45fd2c59a2ba68fec7b34 120 Pfam PF13411 MerR HTH family regulatory protein 1 67 4.0E-20 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS31275 8745a74b81c45fd2c59a2ba68fec7b34 120 Gene3D G3DSA:1.10.1660.10 1 54 1.4E-22 T 29-03-2018 SMALA_RS11935 fe8248a2b0ce9208bea6dfd8e73c23bb 152 PIRSF PIRSF000239 1 152 2.2E-28 T 29-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 SMALA_RS11935 fe8248a2b0ce9208bea6dfd8e73c23bb 152 Gene3D G3DSA:3.40.30.10 1 152 1.7E-40 T 29-03-2018 SMALA_RS11935 fe8248a2b0ce9208bea6dfd8e73c23bb 152 SUPERFAMILY SSF52833 1 152 1.47E-49 T 29-03-2018 IPR012336 Thioredoxin-like fold SMALA_RS11935 fe8248a2b0ce9208bea6dfd8e73c23bb 152 Pfam PF00578 AhpC/TSA family 5 130 2.7E-41 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 SMALA_RS17480 e9663c8a0c611fa71c72c0ae18739807 95 Pfam PF13223 Protein of unknown function (DUF4031) 3 77 5.8E-31 T 29-03-2018 IPR025109 Domain of unknown function DUF4031 SMALA_RS11855 cff27c2560313e5cfd51d2a5cda26cfe 190 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 65 5.3E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS11855 cff27c2560313e5cfd51d2a5cda26cfe 190 Gene3D G3DSA:1.10.357.10 1 190 1.4E-36 T 29-03-2018 SMALA_RS11855 cff27c2560313e5cfd51d2a5cda26cfe 190 SUPERFAMILY SSF48498 86 188 5.34E-13 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS11855 cff27c2560313e5cfd51d2a5cda26cfe 190 SUPERFAMILY SSF46689 8 88 4.14E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS11855 cff27c2560313e5cfd51d2a5cda26cfe 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 5.9E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS11855 cff27c2560313e5cfd51d2a5cda26cfe 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 5.9E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS28230 4918b79db6724a00e6553067efcd587a 278 SUPERFAMILY SSF54713 150 277 1.05E-37 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SMALA_RS28230 4918b79db6724a00e6553067efcd587a 278 Gene3D G3DSA:1.10.8.10 1 56 1.9E-20 T 29-03-2018 SMALA_RS28230 4918b79db6724a00e6553067efcd587a 278 SUPERFAMILY SSF46934 5 55 5.19E-15 T 29-03-2018 IPR009060 UBA-like GO:0005515 SMALA_RS28230 4918b79db6724a00e6553067efcd587a 278 ProSitePatterns PS01127 Elongation factor Ts signature 2. 77 87 - T 29-03-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SMALA_RS28230 4918b79db6724a00e6553067efcd587a 278 Gene3D G3DSA:3.30.479.20 57 150 2.9E-22 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SMALA_RS28230 4918b79db6724a00e6553067efcd587a 278 Gene3D G3DSA:3.30.479.20 231 277 1.7E-12 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SMALA_RS28230 4918b79db6724a00e6553067efcd587a 278 Gene3D G3DSA:3.30.479.20 151 209 8.7E-10 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SMALA_RS28230 4918b79db6724a00e6553067efcd587a 278 ProSitePatterns PS01126 Elongation factor Ts signature 1. 12 27 - T 29-03-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SMALA_RS28230 4918b79db6724a00e6553067efcd587a 278 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 277 2.2E-70 T 29-03-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SMALA_RS28230 4918b79db6724a00e6553067efcd587a 278 Pfam PF00889 Elongation factor TS 73 277 5.0E-62 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SMALA_RS28230 4918b79db6724a00e6553067efcd587a 278 SUPERFAMILY SSF54713 57 147 4.97E-18 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SMALA_RS28230 4918b79db6724a00e6553067efcd587a 278 Gene3D G3DSA:1.10.286.20 210 230 9.6E-15 T 29-03-2018 SMALA_RS28230 4918b79db6724a00e6553067efcd587a 278 Hamap MF_00050 Elongation factor Ts [tsf]. 1 278 63.466 T 29-03-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SMALA_RS16530 3b5d2b982b96838f8c519077b8681741 406 Gene3D G3DSA:3.40.630.10 265 402 2.4E-17 T 29-03-2018 SMALA_RS16530 3b5d2b982b96838f8c519077b8681741 406 Gene3D G3DSA:3.40.630.10 19 252 8.9E-41 T 29-03-2018 SMALA_RS16530 3b5d2b982b96838f8c519077b8681741 406 Pfam PF07687 Peptidase dimerisation domain 204 291 2.8E-6 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain SMALA_RS16530 3b5d2b982b96838f8c519077b8681741 406 SUPERFAMILY SSF55031 200 313 2.39E-21 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain SMALA_RS16530 3b5d2b982b96838f8c519077b8681741 406 Pfam PF01546 Peptidase family M20/M25/M40 87 400 1.6E-26 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 SMALA_RS16530 3b5d2b982b96838f8c519077b8681741 406 SUPERFAMILY SSF53187 315 400 5.94E-63 T 29-03-2018 SMALA_RS16530 3b5d2b982b96838f8c519077b8681741 406 SUPERFAMILY SSF53187 22 214 5.94E-63 T 29-03-2018 SMALA_RS16530 3b5d2b982b96838f8c519077b8681741 406 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 28 392 5.7E-98 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 SMALA_RS16530 3b5d2b982b96838f8c519077b8681741 406 PIRSF PIRSF005962 18 406 2.8E-97 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 SMALA_RS23015 944892a0b73ff76f7275b654bb9f1b12 512 Gene3D G3DSA:2.30.38.10 336 405 6.4E-12 T 29-03-2018 SMALA_RS23015 944892a0b73ff76f7275b654bb9f1b12 512 Gene3D G3DSA:3.40.50.980 9 183 3.9E-33 T 29-03-2018 SMALA_RS23015 944892a0b73ff76f7275b654bb9f1b12 512 ProSitePatterns PS00455 Putative AMP-binding domain signature. 177 188 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS23015 944892a0b73ff76f7275b654bb9f1b12 512 Pfam PF13193 AMP-binding enzyme C-terminal domain 422 496 5.6E-12 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS23015 944892a0b73ff76f7275b654bb9f1b12 512 Gene3D G3DSA:3.40.50.980 184 335 1.6E-31 T 29-03-2018 SMALA_RS23015 944892a0b73ff76f7275b654bb9f1b12 512 Pfam PF00501 AMP-binding enzyme 18 413 6.0E-69 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS23015 944892a0b73ff76f7275b654bb9f1b12 512 SUPERFAMILY SSF56801 11 511 4.06E-114 T 29-03-2018 SMALA_RS23015 944892a0b73ff76f7275b654bb9f1b12 512 Gene3D G3DSA:3.30.300.30 406 511 4.8E-21 T 29-03-2018 SMALA_RS06720 5a59974cdde00d4e96f1bb9694318bea 228 Gene3D G3DSA:1.20.120.530 69 226 2.3E-26 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS06720 5a59974cdde00d4e96f1bb9694318bea 228 SMART SM00345 1 64 1.6E-13 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS06720 5a59974cdde00d4e96f1bb9694318bea 228 Pfam PF07729 FCD domain 89 214 2.9E-18 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS06720 5a59974cdde00d4e96f1bb9694318bea 228 SUPERFAMILY SSF46785 4 68 2.13E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS06720 5a59974cdde00d4e96f1bb9694318bea 228 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 50 1.1E-10 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS06720 5a59974cdde00d4e96f1bb9694318bea 228 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 20 34 1.1E-10 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS06720 5a59974cdde00d4e96f1bb9694318bea 228 Pfam PF00392 Bacterial regulatory proteins, gntR family 4 57 3.0E-17 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS06720 5a59974cdde00d4e96f1bb9694318bea 228 SMART SM00895 89 215 1.6E-16 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS06720 5a59974cdde00d4e96f1bb9694318bea 228 Gene3D G3DSA:1.10.10.10 1 65 1.2E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS06720 5a59974cdde00d4e96f1bb9694318bea 228 SUPERFAMILY SSF48008 88 219 2.88E-21 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS39335 c59a20780213180140d33315874ff8e9 193 Gene3D G3DSA:1.10.10.60 9 56 1.7E-17 T 29-03-2018 SMALA_RS39335 c59a20780213180140d33315874ff8e9 193 Gene3D G3DSA:1.10.10.60 57 158 1.6E-8 T 29-03-2018 SMALA_RS39335 c59a20780213180140d33315874ff8e9 193 SUPERFAMILY SSF46689 10 91 6.67E-18 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS39335 c59a20780213180140d33315874ff8e9 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 70 4.4E-14 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS39335 c59a20780213180140d33315874ff8e9 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 24 37 1.3E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS39335 c59a20780213180140d33315874ff8e9 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 68 1.3E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS38040 997d5bca168f1dc8bbacbfd535badd84 170 SUPERFAMILY SSF46785 26 151 5.79E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS38040 997d5bca168f1dc8bbacbfd535badd84 170 Pfam PF01638 HxlR-like helix-turn-helix 37 125 5.5E-18 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type SMALA_RS38040 997d5bca168f1dc8bbacbfd535badd84 170 Gene3D G3DSA:1.10.10.10 24 169 6.8E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS27870 81678db81a658951dd8e0c78b81acd21 263 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 62 259 1.4E-68 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 SMALA_RS27870 81678db81a658951dd8e0c78b81acd21 263 Gene3D G3DSA:3.90.850.10 31 263 4.9E-86 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 SMALA_RS27870 81678db81a658951dd8e0c78b81acd21 263 Pfam PF10370 Domain of unknown function (DUF2437) 2 57 1.3E-14 T 29-03-2018 IPR018833 Domain of unknown function DUF2437 SMALA_RS27870 81678db81a658951dd8e0c78b81acd21 263 SUPERFAMILY SSF56529 54 260 1.03E-78 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 SMALA_RS42350 2d8b0f278c408d35c526cf986930014b 326 SUPERFAMILY SSF55447 223 322 5.23E-24 T 29-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal SMALA_RS42350 2d8b0f278c408d35c526cf986930014b 326 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 226 316 2.4E-13 T 29-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal SMALA_RS42350 2d8b0f278c408d35c526cf986930014b 326 Gene3D G3DSA:3.30.465.10 53 129 4.1E-17 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SMALA_RS42350 2d8b0f278c408d35c526cf986930014b 326 Gene3D G3DSA:3.30.465.10 134 218 5.1E-16 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SMALA_RS42350 2d8b0f278c408d35c526cf986930014b 326 Gene3D G3DSA:3.30.43.10 1 49 4.8E-16 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 SMALA_RS42350 2d8b0f278c408d35c526cf986930014b 326 SMART SM01092 224 322 2.6E-22 T 29-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal SMALA_RS42350 2d8b0f278c408d35c526cf986930014b 326 Gene3D G3DSA:3.30.390.50 221 322 3.4E-22 T 29-03-2018 SMALA_RS42350 2d8b0f278c408d35c526cf986930014b 326 SUPERFAMILY SSF56176 1 217 1.91E-58 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SMALA_RS42350 2d8b0f278c408d35c526cf986930014b 326 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 3 217 1.9E-47 T 29-03-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 SMALA_RS17630 6a0783d37f76820e59d08d65cf6e24ba 85 SUPERFAMILY SSF46785 2 82 6.39E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS17630 6a0783d37f76820e59d08d65cf6e24ba 85 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.4E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS17630 6a0783d37f76820e59d08d65cf6e24ba 85 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.4E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS17630 6a0783d37f76820e59d08d65cf6e24ba 85 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.4E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS17630 6a0783d37f76820e59d08d65cf6e24ba 85 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 4.1E-19 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS17630 6a0783d37f76820e59d08d65cf6e24ba 85 Gene3D G3DSA:1.10.10.10 1 83 2.3E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS01295 871b44b7a3b711a5fe8d1431defd9882 278 Pfam PF02673 Bacitracin resistance protein BacA 9 265 2.1E-79 T 29-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 SMALA_RS01295 871b44b7a3b711a5fe8d1431defd9882 278 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 9 264 2.0E-71 T 29-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 SMALA_RS01295 871b44b7a3b711a5fe8d1431defd9882 278 Gene3D G3DSA:1.20.1250.20 44 277 2.2E-6 T 29-03-2018 SMALA_RS01295 871b44b7a3b711a5fe8d1431defd9882 278 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 4 271 17.445 T 29-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 SMALA_RS38685 e1824544adb961260f9eee45132a6cae 280 Gene3D G3DSA:3.90.850.10 23 280 8.1E-74 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 SMALA_RS38685 e1824544adb961260f9eee45132a6cae 280 SUPERFAMILY SSF56529 60 279 2.22E-66 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 SMALA_RS38685 e1824544adb961260f9eee45132a6cae 280 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 74 278 1.7E-63 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 SMALA_RS16710 3a6df87dba2106c9955c523e38c88013 538 Pfam PF00149 Calcineurin-like phosphoesterase 317 478 2.4E-11 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 SMALA_RS16710 3a6df87dba2106c9955c523e38c88013 538 Gene3D G3DSA:3.60.21.10 314 537 3.7E-27 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SMALA_RS16710 3a6df87dba2106c9955c523e38c88013 538 SUPERFAMILY SSF56300 313 535 1.18E-37 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SMALA_RS40630 50908698d1a7fbcd3011d7ccc82ff90f 141 Gene3D G3DSA:1.10.10.10 1 138 3.9E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS40630 50908698d1a7fbcd3011d7ccc82ff90f 141 SMART SM00347 25 125 2.3E-17 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS40630 50908698d1a7fbcd3011d7ccc82ff90f 141 PRINTS PR00598 Bacterial regulatory protein MarR family signature 115 135 4.0E-13 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS40630 50908698d1a7fbcd3011d7ccc82ff90f 141 PRINTS PR00598 Bacterial regulatory protein MarR family signature 66 81 4.0E-13 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS40630 50908698d1a7fbcd3011d7ccc82ff90f 141 PRINTS PR00598 Bacterial regulatory protein MarR family signature 85 101 4.0E-13 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS40630 50908698d1a7fbcd3011d7ccc82ff90f 141 PRINTS PR00598 Bacterial regulatory protein MarR family signature 49 65 4.0E-13 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS40630 50908698d1a7fbcd3011d7ccc82ff90f 141 Pfam PF12802 MarR family 30 89 2.0E-12 T 29-03-2018 SMALA_RS40630 50908698d1a7fbcd3011d7ccc82ff90f 141 SUPERFAMILY SSF46785 4 136 1.87E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS18725 c6dca3f177603936203f1996ea28773a 142 Pfam PF09350 Domain of unknown function (DUF1992) 14 79 7.2E-22 T 29-03-2018 IPR018961 DnaJ homologue, subfamily C, member 28, conserved domain SMALA_RS39420 4bc56633ee39bcee48a4b29c9f86342a 539 SUPERFAMILY SSF53067 53 313 2.16E-10 T 29-03-2018 SMALA_RS39420 4bc56633ee39bcee48a4b29c9f86342a 539 Pfam PF06277 Ethanolamine utilisation protein EutA 50 518 6.9E-107 T 29-03-2018 IPR009377 Ethanolamine utilisation EutA SMALA_RS39420 4bc56633ee39bcee48a4b29c9f86342a 539 Gene3D G3DSA:3.30.420.150 196 499 3.1E-9 T 29-03-2018 SMALA_RS39420 4bc56633ee39bcee48a4b29c9f86342a 539 Gene3D G3DSA:3.30.420.40 51 195 5.1E-5 T 29-03-2018 SMALA_RS05485 365f5696aad0b4211ec22c2442500413 264 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 12 185 6.9E-25 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain SMALA_RS05485 365f5696aad0b4211ec22c2442500413 264 Gene3D G3DSA:3.40.50.1110 6 196 2.7E-33 T 29-03-2018 SMALA_RS05485 365f5696aad0b4211ec22c2442500413 264 SUPERFAMILY SSF52266 8 194 1.15E-34 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain SMALA_RS09445 838af52c88894a24ae6495e80a5afd66 106 SUPERFAMILY SSF103481 7 104 3.14E-20 T 29-03-2018 SMALA_RS09445 838af52c88894a24ae6495e80a5afd66 106 Pfam PF00893 Small Multidrug Resistance protein 1 93 5.6E-27 T 29-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 SMALA_RS00735 07ebbb3d7d7a0f6875d19036660a23dc 306 Gene3D G3DSA:3.40.190.10 87 176 5.1E-22 T 29-03-2018 SMALA_RS00735 07ebbb3d7d7a0f6875d19036660a23dc 306 SUPERFAMILY SSF46785 1 84 6.81E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS00735 07ebbb3d7d7a0f6875d19036660a23dc 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.9E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS00735 07ebbb3d7d7a0f6875d19036660a23dc 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.9E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS00735 07ebbb3d7d7a0f6875d19036660a23dc 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.9E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS00735 07ebbb3d7d7a0f6875d19036660a23dc 306 Gene3D G3DSA:3.40.190.10 177 265 1.2E-24 T 29-03-2018 SMALA_RS00735 07ebbb3d7d7a0f6875d19036660a23dc 306 Pfam PF03466 LysR substrate binding domain 88 291 8.4E-45 T 29-03-2018 IPR005119 LysR, substrate-binding SMALA_RS00735 07ebbb3d7d7a0f6875d19036660a23dc 306 Gene3D G3DSA:1.10.10.10 1 83 2.3E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS00735 07ebbb3d7d7a0f6875d19036660a23dc 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 2.4E-25 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS00735 07ebbb3d7d7a0f6875d19036660a23dc 306 SUPERFAMILY SSF53850 89 292 1.32E-42 T 29-03-2018 SMALA_RS38630 831cb8b15b3cb79173a9e646134d1a57 403 Pfam PF13412 Winged helix-turn-helix DNA-binding 23 59 2.2E-5 T 29-03-2018 SMALA_RS38630 831cb8b15b3cb79173a9e646134d1a57 403 Gene3D G3DSA:1.10.10.10 13 77 1.1E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS38630 831cb8b15b3cb79173a9e646134d1a57 403 ProSitePatterns PS01125 ROK family signature. 219 246 - T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 SMALA_RS38630 831cb8b15b3cb79173a9e646134d1a57 403 Gene3D G3DSA:3.30.420.40 205 393 4.0E-49 T 29-03-2018 SMALA_RS38630 831cb8b15b3cb79173a9e646134d1a57 403 SUPERFAMILY SSF46785 18 79 4.14E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS38630 831cb8b15b3cb79173a9e646134d1a57 403 Gene3D G3DSA:3.30.420.40 78 204 1.1E-22 T 29-03-2018 SMALA_RS38630 831cb8b15b3cb79173a9e646134d1a57 403 SUPERFAMILY SSF53067 86 384 8.1E-51 T 29-03-2018 SMALA_RS38630 831cb8b15b3cb79173a9e646134d1a57 403 Pfam PF00480 ROK family 88 381 3.9E-52 T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 SMALA_RS36325 40c99e70b93f94fea180966651b9c0cc 291 SUPERFAMILY SSF161098 17 291 3.08E-70 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS36325 40c99e70b93f94fea180966651b9c0cc 291 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 96 285 5.4E-19 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS36325 40c99e70b93f94fea180966651b9c0cc 291 Gene3D G3DSA:1.10.3720.10 13 279 1.5E-43 T 29-03-2018 SMALA_RS01420 ff7a14ef34bf372d89d617cfc42e680b 619 Pfam PF10096 Uncharacterized protein conserved in bacteria (DUF2334) 337 604 2.9E-59 T 29-03-2018 IPR018763 Protein of unknown function DUF2334 SMALA_RS01420 ff7a14ef34bf372d89d617cfc42e680b 619 Gene3D G3DSA:3.20.20.370 332 619 2.6E-12 T 29-03-2018 SMALA_RS01420 ff7a14ef34bf372d89d617cfc42e680b 619 Gene3D G3DSA:3.40.50.360 73 209 2.0E-4 T 29-03-2018 IPR029039 Flavoprotein-like domain SMALA_RS23150 20cd1f1dc7b71cd1e56ae7b95f6f1f34 167 SUPERFAMILY SSF50249 27 158 1.39E-29 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMALA_RS23150 20cd1f1dc7b71cd1e56ae7b95f6f1f34 167 Gene3D G3DSA:2.40.50.140 79 155 4.8E-13 T 29-03-2018 SMALA_RS23150 20cd1f1dc7b71cd1e56ae7b95f6f1f34 167 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 76 151 2.6E-16 T 29-03-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal SMALA_RS23150 20cd1f1dc7b71cd1e56ae7b95f6f1f34 167 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 43 72 9.9E-10 T 29-03-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal SMALA_RS30715 c862f94ab59d405e84fff77bb5ec2e8d 259 SMART SM00382 34 218 2.4E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS30715 c862f94ab59d405e84fff77bb5ec2e8d 259 SUPERFAMILY SSF52540 5 231 2.3E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS30715 c862f94ab59d405e84fff77bb5ec2e8d 259 Gene3D G3DSA:3.40.50.300 2 252 3.4E-70 T 29-03-2018 SMALA_RS30715 c862f94ab59d405e84fff77bb5ec2e8d 259 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS30715 c862f94ab59d405e84fff77bb5ec2e8d 259 Pfam PF00005 ABC transporter 26 168 2.0E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS27370 7cd332bc798cc68eda0f8bb428bf5f3f 595 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 66 423 3.5E-102 T 29-03-2018 IPR030931 Group II intron reverse transcriptase/maturase SMALA_RS27370 7cd332bc798cc68eda0f8bb428bf5f3f 595 Pfam PF08388 Group II intron, maturase-specific domain 360 436 6.8E-20 T 29-03-2018 IPR013597 Group II intron, maturase-specific SMALA_RS27370 7cd332bc798cc68eda0f8bb428bf5f3f 595 SUPERFAMILY SSF56672 85 424 8.34E-47 T 29-03-2018 SMALA_RS27370 7cd332bc798cc68eda0f8bb428bf5f3f 595 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 121 341 9.1E-43 T 29-03-2018 IPR000477 Reverse transcriptase domain SMALA_RS27370 7cd332bc798cc68eda0f8bb428bf5f3f 595 Pfam PF13655 N-terminal domain of reverse transcriptase 23 104 5.8E-29 T 29-03-2018 IPR025960 Reverse transcriptase, N-terminal domain SMALA_RS27370 7cd332bc798cc68eda0f8bb428bf5f3f 595 Gene3D G3DSA:3.40.1800.10 493 590 1.8E-9 T 29-03-2018 SMALA_RS27370 7cd332bc798cc68eda0f8bb428bf5f3f 595 Pfam PF01844 HNH endonuclease 545 578 1.3E-7 T 29-03-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 SMALA_RS27370 7cd332bc798cc68eda0f8bb428bf5f3f 595 Gene3D G3DSA:3.30.70.270 146 341 1.9E-29 T 29-03-2018 SMALA_RS36575 27e1be0928d801851c2f0827287474fd 623 Gene3D G3DSA:3.40.50.720 118 266 2.2E-10 T 29-03-2018 SMALA_RS36575 27e1be0928d801851c2f0827287474fd 623 Gene3D G3DSA:3.40.50.720 380 518 1.5E-11 T 29-03-2018 SMALA_RS36575 27e1be0928d801851c2f0827287474fd 623 Gene3D G3DSA:3.30.70.1450 301 366 0.024 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 SMALA_RS36575 27e1be0928d801851c2f0827287474fd 623 SUPERFAMILY SSF51735 386 529 1.18E-7 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS36575 27e1be0928d801851c2f0827287474fd 623 Pfam PF06241 Castor and Pollux, part of voltage-gated ion channel 269 362 9.4E-20 T 29-03-2018 IPR010420 CASTOR/POLLUX/SYM8 ion channels SMALA_RS16215 ac212f270f1e176f28be2c794b1b0496 231 SUPERFAMILY SSF54106 183 230 1.7E-6 T 29-03-2018 IPR018392 LysM domain SMALA_RS16215 ac212f270f1e176f28be2c794b1b0496 231 Pfam PF01476 LysM domain 184 230 6.4E-10 T 29-03-2018 IPR018392 LysM domain SMALA_RS16215 ac212f270f1e176f28be2c794b1b0496 231 SMART SM00257 183 231 2.5E-8 T 29-03-2018 IPR018392 LysM domain SMALA_RS16215 ac212f270f1e176f28be2c794b1b0496 231 SUPERFAMILY SSF53955 41 118 4.64E-32 T 29-03-2018 IPR023346 Lysozyme-like domain SMALA_RS16215 ac212f270f1e176f28be2c794b1b0496 231 Gene3D G3DSA:1.10.530.10 7 123 6.2E-30 T 29-03-2018 SMALA_RS16215 ac212f270f1e176f28be2c794b1b0496 231 Gene3D G3DSA:3.10.350.10 178 231 5.7E-12 T 29-03-2018 SMALA_RS16215 ac212f270f1e176f28be2c794b1b0496 231 Pfam PF06737 Transglycosylase-like domain 40 116 1.5E-35 T 29-03-2018 IPR010618 Transglycosylase-like SMALA_RS07220 04a5599d31ba762fea9750fda04c5df4 124 Gene3D G3DSA:3.10.50.40 4 124 7.9E-38 T 29-03-2018 SMALA_RS07220 04a5599d31ba762fea9750fda04c5df4 124 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 30 122 6.2E-30 T 29-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain SMALA_RS07220 04a5599d31ba762fea9750fda04c5df4 124 SUPERFAMILY SSF54534 16 124 6.68E-37 T 29-03-2018 SMALA_RS11165 947afb7e7f521eefd34403fe90c706fc 338 Pfam PF00144 Beta-lactamase 43 329 2.0E-63 T 29-03-2018 IPR001466 Beta-lactamase-related SMALA_RS11165 947afb7e7f521eefd34403fe90c706fc 338 Gene3D G3DSA:3.40.710.10 1 338 1.4E-73 T 29-03-2018 SMALA_RS11165 947afb7e7f521eefd34403fe90c706fc 338 SUPERFAMILY SSF56601 46 321 7.23E-72 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMALA_RS38735 65100f8e6c3a2fdb4bbea87cdf655963 509 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 262 269 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 SMALA_RS38735 65100f8e6c3a2fdb4bbea87cdf655963 509 Gene3D G3DSA:3.40.605.10 8 278 9.1E-77 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS38735 65100f8e6c3a2fdb4bbea87cdf655963 509 SUPERFAMILY SSF53720 28 496 7.2E-134 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMALA_RS38735 65100f8e6c3a2fdb4bbea87cdf655963 509 Pfam PF00171 Aldehyde dehydrogenase family 33 489 2.1E-129 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS38735 65100f8e6c3a2fdb4bbea87cdf655963 509 Gene3D G3DSA:3.40.309.10 279 478 1.0E-54 T 29-03-2018 SMALA_RS39015 4319049c324f3fb2cd1e9abbaee81a0c 321 Gene3D G3DSA:3.30.420.40 149 321 2.1E-31 T 29-03-2018 SMALA_RS39015 4319049c324f3fb2cd1e9abbaee81a0c 321 SUPERFAMILY SSF53067 37 318 7.33E-31 T 29-03-2018 SMALA_RS39015 4319049c324f3fb2cd1e9abbaee81a0c 321 Pfam PF00480 ROK family 37 317 8.0E-29 T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 SMALA_RS39015 4319049c324f3fb2cd1e9abbaee81a0c 321 Gene3D G3DSA:3.30.420.40 24 148 5.3E-19 T 29-03-2018 SMALA_RS11420 e71b13ba225fe091730ee4fbe3f09caa 244 Pfam PF08241 Methyltransferase domain 18 121 7.4E-23 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 SMALA_RS11420 e71b13ba225fe091730ee4fbe3f09caa 244 SUPERFAMILY SSF53335 9 236 6.97E-42 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS11420 e71b13ba225fe091730ee4fbe3f09caa 244 Gene3D G3DSA:3.40.50.150 4 180 3.2E-35 T 29-03-2018 SMALA_RS13020 0497904da06bd565a5916dcdf6787de7 373 Gene3D G3DSA:1.10.150.320 316 372 3.3E-19 T 29-03-2018 SMALA_RS13020 0497904da06bd565a5916dcdf6787de7 373 SUPERFAMILY SSF47781 297 369 9.0E-26 T 29-03-2018 IPR010994 RuvA domain 2-like SMALA_RS13020 0497904da06bd565a5916dcdf6787de7 373 Pfam PF12836 Helix-hairpin-helix motif 312 371 3.7E-20 T 29-03-2018 SMALA_RS13020 0497904da06bd565a5916dcdf6787de7 373 Gene3D G3DSA:3.10.560.10 213 315 6.9E-10 T 29-03-2018 SMALA_RS13020 0497904da06bd565a5916dcdf6787de7 373 Pfam PF10531 SLBB domain 218 270 1.5E-10 T 29-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS10940 5442311d5c9019f0c524c912417e8848 453 Gene3D G3DSA:3.10.20.70 1 103 3.8E-33 T 29-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SMALA_RS10940 5442311d5c9019f0c524c912417e8848 453 SUPERFAMILY SSF54368 8 103 3.01E-30 T 29-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SMALA_RS10940 5442311d5c9019f0c524c912417e8848 453 Gene3D G3DSA:3.30.590.10 104 453 1.5E-110 T 29-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 SMALA_RS10940 5442311d5c9019f0c524c912417e8848 453 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 16 98 6.6E-28 T 29-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SMALA_RS10940 5442311d5c9019f0c524c912417e8848 453 Pfam PF00120 Glutamine synthetase, catalytic domain 105 448 1.4E-123 T 29-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SMALA_RS10940 5442311d5c9019f0c524c912417e8848 453 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 232 247 - T 29-03-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 SMALA_RS10940 5442311d5c9019f0c524c912417e8848 453 SMART SM01230 104 363 1.5E-119 T 29-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SMALA_RS10940 5442311d5c9019f0c524c912417e8848 453 SUPERFAMILY SSF55931 106 450 6.77E-113 T 29-03-2018 SMALA_RS34595 1ead7c548d46745cf3b62e1fc0c75365 852 SUPERFAMILY SSF52540 695 844 9.8E-17 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS34595 1ead7c548d46745cf3b62e1fc0c75365 852 SUPERFAMILY SSF52540 470 522 9.8E-17 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS34595 1ead7c548d46745cf3b62e1fc0c75365 852 Pfam PF13558 Putative exonuclease SbcCD, C subunit 743 807 1.7E-13 T 29-03-2018 SMALA_RS34595 1ead7c548d46745cf3b62e1fc0c75365 852 Gene3D G3DSA:3.40.50.300 173 851 2.5E-16 T 29-03-2018 SMALA_RS24895 c75b13c78c583485cb8bc20aa84d34bf 220 SUPERFAMILY SSF53335 10 203 3.95E-32 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS24895 c75b13c78c583485cb8bc20aa84d34bf 220 Pfam PF13489 Methyltransferase domain 49 151 4.5E-15 T 29-03-2018 SMALA_RS24895 c75b13c78c583485cb8bc20aa84d34bf 220 Gene3D G3DSA:3.40.50.150 2 214 5.4E-30 T 29-03-2018 SMALA_RS16060 bbb685c74a272f3e7518efdfa112c88e 311 SUPERFAMILY SSF47413 30 80 1.22E-7 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS16060 bbb685c74a272f3e7518efdfa112c88e 311 Pfam PF13560 Helix-turn-helix domain 6 85 1.5E-15 T 29-03-2018 SMALA_RS16060 bbb685c74a272f3e7518efdfa112c88e 311 SMART SM00530 10 82 1.8E-7 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS16060 bbb685c74a272f3e7518efdfa112c88e 311 Gene3D G3DSA:1.10.260.40 3 86 6.3E-16 T 29-03-2018 SMALA_RS08300 3fa36940c941f606e1df8369912e59f4 438 SUPERFAMILY SSF48452 87 420 6.95E-17 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS08300 3fa36940c941f606e1df8369912e59f4 438 Gene3D G3DSA:1.25.40.10 50 97 0.0062 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS08300 3fa36940c941f606e1df8369912e59f4 438 SMART SM00028 386 419 0.27 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS08300 3fa36940c941f606e1df8369912e59f4 438 SMART SM00028 214 247 26.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS08300 3fa36940c941f606e1df8369912e59f4 438 SMART SM00028 68 108 370.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS08300 3fa36940c941f606e1df8369912e59f4 438 SMART SM00028 110 143 71.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS08300 3fa36940c941f606e1df8369912e59f4 438 Gene3D G3DSA:1.25.40.10 368 437 3.3E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS08300 3fa36940c941f606e1df8369912e59f4 438 Gene3D G3DSA:1.25.40.10 98 165 8.3E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS08300 3fa36940c941f606e1df8369912e59f4 438 Gene3D G3DSA:1.25.40.10 166 312 2.3E-15 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS08300 3fa36940c941f606e1df8369912e59f4 438 Gene3D G3DSA:1.25.40.10 313 367 0.044 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS18385 2ef5112ead2b18310432f802e988dc0c 353 Gene3D G3DSA:3.90.230.10 205 353 1.3E-5 T 29-03-2018 SMALA_RS18385 2ef5112ead2b18310432f802e988dc0c 353 SUPERFAMILY SSF55920 153 348 1.03E-7 T 29-03-2018 IPR000994 Peptidase M24 SMALA_RS18385 2ef5112ead2b18310432f802e988dc0c 353 Gene3D G3DSA:3.40.350.10 4 151 5.5E-11 T 29-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal SMALA_RS18385 2ef5112ead2b18310432f802e988dc0c 353 SUPERFAMILY SSF53092 13 153 1.28E-8 T 29-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal SMALA_RS08115 e465208ac5919add2d2f3815e6b464ae 130 Pfam PF01638 HxlR-like helix-turn-helix 29 115 2.7E-23 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type SMALA_RS08115 e465208ac5919add2d2f3815e6b464ae 130 SUPERFAMILY SSF46785 17 125 1.13E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS08115 e465208ac5919add2d2f3815e6b464ae 130 Gene3D G3DSA:1.10.10.10 26 127 5.2E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS24015 6603ffd7950889539bb74bbbd89b6f51 274 Gene3D G3DSA:3.40.50.150 2 194 3.1E-30 T 29-03-2018 SMALA_RS24015 6603ffd7950889539bb74bbbd89b6f51 274 Hamap MF_00560 Trans-aconitate 2-methyltransferase [tam]. 5 272 43.332 T 29-03-2018 IPR023506 Trans-aconitate 2-methyltransferase GO:0030798 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 SMALA_RS24015 6603ffd7950889539bb74bbbd89b6f51 274 Gene3D G3DSA:1.10.150.290 195 252 3.9E-29 T 29-03-2018 IPR023149 Trans-aconitate 2-methyltransferase, C-terminal GO:0030798 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 SMALA_RS24015 6603ffd7950889539bb74bbbd89b6f51 274 Pfam PF13649 Methyltransferase domain 43 138 4.0E-14 T 29-03-2018 SMALA_RS24015 6603ffd7950889539bb74bbbd89b6f51 274 SUPERFAMILY SSF53335 5 248 2.59E-31 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS15590 d592470703c1abb8e01e73a1262d3868 351 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 67 206 4.5E-27 T 29-03-2018 IPR006342 Methyltransferase FkbM SMALA_RS15590 d592470703c1abb8e01e73a1262d3868 351 Pfam PF05050 Methyltransferase FkbM domain 69 207 3.4E-17 T 29-03-2018 IPR006342 Methyltransferase FkbM SMALA_RS15590 d592470703c1abb8e01e73a1262d3868 351 Gene3D G3DSA:3.40.50.150 47 247 5.0E-32 T 29-03-2018 SMALA_RS15590 d592470703c1abb8e01e73a1262d3868 351 SUPERFAMILY SSF53335 60 234 9.52E-39 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS38210 0b91dbc79b4db1fe54b7f86d721ed616 313 SUPERFAMILY SSF51197 17 306 1.97E-70 T 29-03-2018 SMALA_RS38210 0b91dbc79b4db1fe54b7f86d721ed616 313 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 19 304 1.5E-44 T 29-03-2018 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 SMALA_RS38210 0b91dbc79b4db1fe54b7f86d721ed616 313 Gene3D G3DSA:3.60.130.10 7 308 3.0E-66 T 29-03-2018 SMALA_RS04730 8593b176d0372ab0a93ba1ca3137303f 288 SUPERFAMILY SSF51735 1 279 1.49E-47 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS04730 8593b176d0372ab0a93ba1ca3137303f 288 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 215 8.3E-24 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 SMALA_RS04730 8593b176d0372ab0a93ba1ca3137303f 288 Gene3D G3DSA:3.40.50.720 2 284 3.4E-38 T 29-03-2018 SMALA_RS00405 ec6810ed962e5ef83eea0d634190e112 578 Gene3D G3DSA:3.40.630.30 81 549 4.3E-5 T 29-03-2018 SMALA_RS09885 6ef44a2545f9eb5782c90a1480f3ea1f 113 TIGRFAM TIGR01795 CM_mono_cladeE: chorismate mutase 14 104 2.7E-47 T 29-03-2018 IPR010951 Chorismate mutase, bacteria SMALA_RS09885 6ef44a2545f9eb5782c90a1480f3ea1f 113 SMART SM00830 21 101 7.6E-22 T 29-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 SMALA_RS09885 6ef44a2545f9eb5782c90a1480f3ea1f 113 Gene3D G3DSA:1.20.59.10 9 110 2.3E-27 T 29-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 SMALA_RS09885 6ef44a2545f9eb5782c90a1480f3ea1f 113 Pfam PF01817 Chorismate mutase type II 21 96 4.0E-17 T 29-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 SMALA_RS09885 6ef44a2545f9eb5782c90a1480f3ea1f 113 SUPERFAMILY SSF48600 10 100 4.73E-25 T 29-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 SMALA_RS31180 4f8cad611e7f3b71551ef74aa9eb1509 404 SUPERFAMILY SSF81606 159 364 7.85E-6 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS31180 4f8cad611e7f3b71551ef74aa9eb1509 404 SMART SM00331 143 366 8.7E-21 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS31180 4f8cad611e7f3b71551ef74aa9eb1509 404 Gene3D G3DSA:3.60.40.10 107 367 4.8E-23 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS31180 4f8cad611e7f3b71551ef74aa9eb1509 404 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 170 365 1.0E-36 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS31885 b895002cfd3e0329b97268b907c6fbaa 226 Gene3D G3DSA:1.10.3630.10 2 189 4.0E-29 T 29-03-2018 SMALA_RS31885 b895002cfd3e0329b97268b907c6fbaa 226 Pfam PF05719 Golgi phosphoprotein 3 (GPP34) 8 203 5.8E-32 T 29-03-2018 IPR008628 Golgi phosphoprotein 3-like GO:0070273 SMALA_RS07095 7dca96e3658e0f1c313a23b07fe18eaa 359 SUPERFAMILY SSF53098 180 326 1.41E-16 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SMALA_RS07095 7dca96e3658e0f1c313a23b07fe18eaa 359 SUPERFAMILY SSF46689 77 153 2.87E-5 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS07095 7dca96e3658e0f1c313a23b07fe18eaa 359 Gene3D G3DSA:3.30.420.10 168 335 1.4E-18 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SMALA_RS07095 7dca96e3658e0f1c313a23b07fe18eaa 359 Pfam PF13683 Integrase core domain 268 325 1.4E-12 T 29-03-2018 IPR001584 Integrase, catalytic core GO:0015074 SMALA_RS39190 bc37d2f05db3d351f64632b0095fde86 448 TIGRFAM TIGR03217 4OH_2_O_val_ald: 4-hydroxy-2-oxovalerate aldolase 16 343 1.1E-114 T 29-03-2018 IPR017629 4-hydroxy-2-oxovalerate aldolase GO:0008701|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 SMALA_RS39190 bc37d2f05db3d351f64632b0095fde86 448 Hamap MF_01656 4-hydroxy-2-oxovalerate aldolase [mhpE]. 1 350 140.973 T 29-03-2018 IPR017629 4-hydroxy-2-oxovalerate aldolase GO:0008701|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 SMALA_RS39190 bc37d2f05db3d351f64632b0095fde86 448 Pfam PF00550 Phosphopantetheine attachment site 362 428 8.8E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS39190 bc37d2f05db3d351f64632b0095fde86 448 Gene3D G3DSA:1.10.1200.10 354 448 8.1E-16 T 29-03-2018 SMALA_RS39190 bc37d2f05db3d351f64632b0095fde86 448 SUPERFAMILY SSF47336 355 446 1.14E-16 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS39190 bc37d2f05db3d351f64632b0095fde86 448 ProDom PD005364 ALDOLASE 4-HYDROXY-2-OXOVALERATE LYASE PYRUVATE 4.1.3.- PLASMID HMG-COA LYASE-LIKE TRANSFERASE HOA 280 341 2.0E-22 T 29-03-2018 IPR012425 DmpG-like communication GO:0016833|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 SMALA_RS39190 bc37d2f05db3d351f64632b0095fde86 448 Pfam PF07836 DmpG-like communication domain 281 342 1.9E-23 T 29-03-2018 IPR012425 DmpG-like communication GO:0016833|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 SMALA_RS39190 bc37d2f05db3d351f64632b0095fde86 448 Pfam PF00682 HMGL-like 18 270 1.3E-45 T 29-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 SMALA_RS39190 bc37d2f05db3d351f64632b0095fde86 448 ProSitePatterns PS00012 Phosphopantetheine attachment site. 387 402 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS39190 bc37d2f05db3d351f64632b0095fde86 448 SUPERFAMILY SSF51569 13 294 4.58E-63 T 29-03-2018 SMALA_RS39190 bc37d2f05db3d351f64632b0095fde86 448 Gene3D G3DSA:3.20.20.70 15 288 1.9E-52 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS39190 bc37d2f05db3d351f64632b0095fde86 448 Gene3D G3DSA:1.10.8.60 289 345 5.6E-20 T 29-03-2018 SMALA_RS39190 bc37d2f05db3d351f64632b0095fde86 448 SUPERFAMILY SSF89000 296 344 7.06E-13 T 29-03-2018 SMALA_RS18275 566326a380f92e9d11208c09d47a1458 169 Pfam PF04138 GtrA-like protein 51 164 1.7E-25 T 29-03-2018 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 SMALA_RS12005 465014f89dced8d4c92c46a2f1b3e871 151 Gene3D G3DSA:1.10.1660.10 26 84 3.9E-18 T 29-03-2018 SMALA_RS12005 465014f89dced8d4c92c46a2f1b3e871 151 SUPERFAMILY SSF46955 30 144 4.03E-29 T 29-03-2018 IPR009061 Putative DNA-binding domain SMALA_RS12005 465014f89dced8d4c92c46a2f1b3e871 151 Gene3D G3DSA:1.10.1660.10 85 151 1.6E-14 T 29-03-2018 SMALA_RS12005 465014f89dced8d4c92c46a2f1b3e871 151 Pfam PF13411 MerR HTH family regulatory protein 30 91 2.0E-15 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS12005 465014f89dced8d4c92c46a2f1b3e871 151 SMART SM00422 30 99 2.2E-15 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS14180 ed3e882f56376730c55bb0d1a7c904da 385 SUPERFAMILY SSF56645 4 247 5.63E-79 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMALA_RS14180 ed3e882f56376730c55bb0d1a7c904da 385 Gene3D G3DSA:1.10.540.10 3 123 8.4E-35 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS14180 ed3e882f56376730c55bb0d1a7c904da 385 Gene3D G3DSA:2.40.110.10 124 224 3.0E-34 T 29-03-2018 SMALA_RS14180 ed3e882f56376730c55bb0d1a7c904da 385 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 119 1.2E-34 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS14180 ed3e882f56376730c55bb0d1a7c904da 385 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 239 383 5.0E-39 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMALA_RS14180 ed3e882f56376730c55bb0d1a7c904da 385 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 342 361 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 SMALA_RS14180 ed3e882f56376730c55bb0d1a7c904da 385 PIRSF PIRSF016578 1 384 4.7E-12 T 29-03-2018 SMALA_RS14180 ed3e882f56376730c55bb0d1a7c904da 385 SUPERFAMILY SSF47203 233 383 1.1E-46 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMALA_RS14180 ed3e882f56376730c55bb0d1a7c904da 385 Gene3D G3DSA:1.20.140.10 225 384 1.1E-51 T 29-03-2018 SMALA_RS14180 ed3e882f56376730c55bb0d1a7c904da 385 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 223 1.1E-24 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 SMALA_RS25195 f5735d5b62e66c5b4b78a9411a688ae3 145 SUPERFAMILY SSF54197 3 130 7.27E-32 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 SMALA_RS25195 f5735d5b62e66c5b4b78a9411a688ae3 145 Pfam PF01230 HIT domain 11 98 9.1E-17 T 29-03-2018 IPR001310 Histidine triad (HIT) protein SMALA_RS25195 f5735d5b62e66c5b4b78a9411a688ae3 145 Gene3D G3DSA:3.30.428.10 3 134 2.9E-27 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 SMALA_RS25195 f5735d5b62e66c5b4b78a9411a688ae3 145 PRINTS PR00332 Histidine triad family signature 87 97 6.1E-12 T 29-03-2018 IPR001310 Histidine triad (HIT) protein SMALA_RS25195 f5735d5b62e66c5b4b78a9411a688ae3 145 PRINTS PR00332 Histidine triad family signature 25 43 6.1E-12 T 29-03-2018 IPR001310 Histidine triad (HIT) protein SMALA_RS25195 f5735d5b62e66c5b4b78a9411a688ae3 145 PRINTS PR00332 Histidine triad family signature 4 20 6.1E-12 T 29-03-2018 IPR001310 Histidine triad (HIT) protein SMALA_RS40095 a4f3ff423f13d43cd0649dcf744f7856 225 Pfam PF03737 Aldolase/RraA 26 172 1.0E-34 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein SMALA_RS40095 a4f3ff423f13d43cd0649dcf744f7856 225 Gene3D G3DSA:3.50.30.40 17 192 1.7E-46 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein SMALA_RS40095 a4f3ff423f13d43cd0649dcf744f7856 225 SUPERFAMILY SSF89562 21 182 3.53E-41 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein SMALA_RS23185 4ec4c5820f06b2d1fcc9ac45730ccec1 349 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 298 314 9.6E-6 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SMALA_RS23185 4ec4c5820f06b2d1fcc9ac45730ccec1 349 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 283 298 9.6E-6 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SMALA_RS23185 4ec4c5820f06b2d1fcc9ac45730ccec1 349 SMART SM00342 229 314 5.3E-25 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS23185 4ec4c5820f06b2d1fcc9ac45730ccec1 349 Pfam PF14525 AraC-binding-like domain 20 194 1.5E-21 T 29-03-2018 IPR035418 Transcription regulator HTH, AraC- type, ligand binding domain-like SMALA_RS23185 4ec4c5820f06b2d1fcc9ac45730ccec1 349 Gene3D G3DSA:1.10.10.60 207 265 9.5E-9 T 29-03-2018 SMALA_RS23185 4ec4c5820f06b2d1fcc9ac45730ccec1 349 Pfam PF12833 Helix-turn-helix domain 235 314 1.4E-22 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS23185 4ec4c5820f06b2d1fcc9ac45730ccec1 349 SUPERFAMILY SSF46689 265 315 1.74E-9 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS23185 4ec4c5820f06b2d1fcc9ac45730ccec1 349 Gene3D G3DSA:1.10.10.60 266 317 2.0E-14 T 29-03-2018 SMALA_RS23185 4ec4c5820f06b2d1fcc9ac45730ccec1 349 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 265 310 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 SMALA_RS00150 080823c3eca89343378f0c6cf744081e 163 Pfam PF16571 FBP C-terminal treble-clef zinc-finger 8 161 8.5E-62 T 29-03-2018 IPR032330 Elongation factor G-binding protein, C-terminal treble-clef zinc-finger SMALA_RS23340 87b73f5b1501031054a41480d65b4fd0 296 Gene3D G3DSA:3.30.470.30 7 135 1.4E-26 T 29-03-2018 SMALA_RS23340 87b73f5b1501031054a41480d65b4fd0 296 Gene3D G3DSA:3.30.1490.70 136 189 1.5E-10 T 29-03-2018 SMALA_RS23340 87b73f5b1501031054a41480d65b4fd0 296 Pfam PF01068 ATP dependent DNA ligase domain 15 187 4.1E-23 T 29-03-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 SMALA_RS23340 87b73f5b1501031054a41480d65b4fd0 296 SUPERFAMILY SSF56091 14 187 1.73E-37 T 29-03-2018 SMALA_RS09410 7a9ba5fcd5af91d29c8f686c4be5612b 407 Pfam PF02342 TerD domain 21 158 1.6E-28 T 29-03-2018 IPR003325 TerD domain GO:0006950 SMALA_RS09410 7a9ba5fcd5af91d29c8f686c4be5612b 407 Pfam PF02342 TerD domain 225 393 3.9E-39 T 29-03-2018 IPR003325 TerD domain GO:0006950 SMALA_RS09410 7a9ba5fcd5af91d29c8f686c4be5612b 407 Gene3D G3DSA:2.60.60.30 6 157 2.0E-34 T 29-03-2018 SMALA_RS09410 7a9ba5fcd5af91d29c8f686c4be5612b 407 Gene3D G3DSA:2.60.60.30 242 401 2.1E-41 T 29-03-2018 SMALA_RS04635 cafe72b64f323f3b012c8b9ddb730cec 405 Pfam PF07730 Histidine kinase 211 278 1.3E-13 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMALA_RS04635 cafe72b64f323f3b012c8b9ddb730cec 405 SUPERFAMILY SSF55874 286 400 8.63E-9 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS04635 cafe72b64f323f3b012c8b9ddb730cec 405 Gene3D G3DSA:3.30.565.10 276 402 3.0E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS24420 a5a3e0eacd2dda117e9fc71c11c7bbde 678 SUPERFAMILY SSF48208 191 538 1.94E-69 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 SMALA_RS24420 a5a3e0eacd2dda117e9fc71c11c7bbde 678 Gene3D G3DSA:3.40.30.10 1 170 3.2E-31 T 29-03-2018 SMALA_RS24420 a5a3e0eacd2dda117e9fc71c11c7bbde 678 Gene3D G3DSA:1.50.10.10 220 347 7.3E-28 T 29-03-2018 SMALA_RS24420 a5a3e0eacd2dda117e9fc71c11c7bbde 678 Gene3D G3DSA:1.50.10.10 348 587 1.4E-25 T 29-03-2018 SMALA_RS24420 a5a3e0eacd2dda117e9fc71c11c7bbde 678 Pfam PF03190 Protein of unknown function, DUF255 3 163 2.9E-74 T 29-03-2018 IPR004879 Domain of unknown function DUF255 SMALA_RS24420 a5a3e0eacd2dda117e9fc71c11c7bbde 678 SUPERFAMILY SSF52833 1 127 4.64E-30 T 29-03-2018 IPR012336 Thioredoxin-like fold SMALA_RS24420 a5a3e0eacd2dda117e9fc71c11c7bbde 678 PIRSF PIRSF006402 1 677 3.1E-201 T 29-03-2018 IPR024705 Spermatogenesis-associated protein 20 SMALA_RS21090 01bae46a3569427c9d9d40c64fe0d69b 430 Gene3D G3DSA:3.60.40.10 101 363 1.0E-33 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS21090 01bae46a3569427c9d9d40c64fe0d69b 430 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 164 360 3.0E-44 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS21090 01bae46a3569427c9d9d40c64fe0d69b 430 SMART SM00331 135 360 5.5E-30 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS21090 01bae46a3569427c9d9d40c64fe0d69b 430 SUPERFAMILY SSF81606 151 359 8.63E-8 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS40840 f4a8de5ab62e1f4bf8801f29644b7064 336 Gene3D G3DSA:3.40.50.2300 51 170 8.8E-26 T 29-03-2018 SMALA_RS40840 f4a8de5ab62e1f4bf8801f29644b7064 336 SUPERFAMILY SSF53822 57 331 4.38E-61 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SMALA_RS40840 f4a8de5ab62e1f4bf8801f29644b7064 336 Gene3D G3DSA:3.40.50.2300 171 332 8.6E-29 T 29-03-2018 SMALA_RS40840 f4a8de5ab62e1f4bf8801f29644b7064 336 Pfam PF13407 Periplasmic binding protein domain 58 309 5.6E-49 T 29-03-2018 IPR025997 Periplasmic binding protein SMALA_RS07150 715f2ee5158ebe9bd9a8bb1cea3e944f 531 SUPERFAMILY SSF140864 14 340 4.32E-45 T 29-03-2018 SMALA_RS07150 715f2ee5158ebe9bd9a8bb1cea3e944f 531 Pfam PF05731 TROVE domain 230 321 2.1E-15 T 29-03-2018 IPR008858 TROVE domain GO:0003723 SMALA_RS07150 715f2ee5158ebe9bd9a8bb1cea3e944f 531 Gene3D G3DSA:3.40.50.410 327 516 1.5E-14 T 29-03-2018 IPR002035 von Willebrand factor, type A SMALA_RS07150 715f2ee5158ebe9bd9a8bb1cea3e944f 531 SUPERFAMILY SSF53300 344 511 5.78E-16 T 29-03-2018 IPR002035 von Willebrand factor, type A SMALA_RS38270 fa5e113ffa610375caa8755b1689ab03 342 Gene3D G3DSA:3.30.1780.10 1 145 8.1E-31 T 29-03-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 SMALA_RS38270 fa5e113ffa610375caa8755b1689ab03 342 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 17 319 1.1E-53 T 29-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 SMALA_RS38270 fa5e113ffa610375caa8755b1689ab03 342 Gene3D G3DSA:3.40.50.720 146 301 6.3E-19 T 29-03-2018 SMALA_RS38270 fa5e113ffa610375caa8755b1689ab03 342 PIRSF PIRSF001439 9 329 3.3E-52 T 29-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 SMALA_RS38270 fa5e113ffa610375caa8755b1689ab03 342 SUPERFAMILY SSF51735 1 332 1.31E-77 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS05065 eacdf0d04089f647e4a39d0cba535354 198 SUPERFAMILY SSF46689 5 87 3.02E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS05065 eacdf0d04089f647e4a39d0cba535354 198 Gene3D G3DSA:1.10.357.10 64 196 3.9E-24 T 29-03-2018 SMALA_RS05065 eacdf0d04089f647e4a39d0cba535354 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 63 1.7E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS05065 eacdf0d04089f647e4a39d0cba535354 198 Gene3D G3DSA:1.10.10.60 14 63 5.0E-15 T 29-03-2018 SMALA_RS05065 eacdf0d04089f647e4a39d0cba535354 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 2.0E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS05065 eacdf0d04089f647e4a39d0cba535354 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 2.0E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS15650 48b8836ac64fc2758c40893555373573 215 Gene3D G3DSA:3.40.630.30 2 184 1.5E-34 T 29-03-2018 SMALA_RS15650 48b8836ac64fc2758c40893555373573 215 SUPERFAMILY SSF55729 1 178 3.3E-44 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS15650 48b8836ac64fc2758c40893555373573 215 Pfam PF13302 Acetyltransferase (GNAT) domain 10 154 1.7E-30 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SMALA_RS04030 37055a09a432f5cc0e18163aa9373858 290 Pfam PF00561 alpha/beta hydrolase fold 27 269 2.9E-25 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS04030 37055a09a432f5cc0e18163aa9373858 290 Gene3D G3DSA:3.40.50.1820 3 287 2.5E-50 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS04030 37055a09a432f5cc0e18163aa9373858 290 PRINTS PR00412 Epoxide hydrolase signature 260 282 1.4E-8 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS04030 37055a09a432f5cc0e18163aa9373858 290 PRINTS PR00412 Epoxide hydrolase signature 113 126 1.4E-8 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS04030 37055a09a432f5cc0e18163aa9373858 290 PRINTS PR00412 Epoxide hydrolase signature 33 51 1.4E-8 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS04030 37055a09a432f5cc0e18163aa9373858 290 PRINTS PR00412 Epoxide hydrolase signature 99 112 1.4E-8 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS04030 37055a09a432f5cc0e18163aa9373858 290 SUPERFAMILY SSF53474 3 284 9.12E-70 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS12270 077e59843c3db6b3f4b1d82d4d440d14 273 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 86 266 4.5E-23 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS12270 077e59843c3db6b3f4b1d82d4d440d14 273 Gene3D G3DSA:1.10.3720.10 3 260 5.2E-42 T 29-03-2018 SMALA_RS12270 077e59843c3db6b3f4b1d82d4d440d14 273 SUPERFAMILY SSF161098 7 273 4.19E-71 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS32220 7eacf65622ccdb1d9630504c6b6a9633 288 PIRSF PIRSF036551 7 288 4.2E-111 T 29-03-2018 IPR000400 Glycoside hydrolase, family 46 GO:0005576|GO:0005975|GO:0016977 KEGG: 00520+3.2.1.132 SMALA_RS32220 7eacf65622ccdb1d9630504c6b6a9633 288 Gene3D G3DSA:3.30.386.10 49 154 3.1E-53 T 29-03-2018 SMALA_RS32220 7eacf65622ccdb1d9630504c6b6a9633 288 SUPERFAMILY SSF53955 52 287 3.66E-94 T 29-03-2018 IPR023346 Lysozyme-like domain SMALA_RS32220 7eacf65622ccdb1d9630504c6b6a9633 288 Pfam PF01374 Glycosyl hydrolase family 46 66 275 4.9E-104 T 29-03-2018 IPR000400 Glycoside hydrolase, family 46 GO:0005576|GO:0005975|GO:0016977 KEGG: 00520+3.2.1.132 SMALA_RS32220 7eacf65622ccdb1d9630504c6b6a9633 288 Gene3D G3DSA:1.20.141.10 155 282 1.3E-57 T 29-03-2018 SMALA_RS02730 6ff2e7700127b9ec3af52df08c905bc2 255 SMART SM00382 43 229 5.1E-18 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS02730 6ff2e7700127b9ec3af52df08c905bc2 255 Pfam PF00005 ABC transporter 34 180 5.4E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS02730 6ff2e7700127b9ec3af52df08c905bc2 255 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS02730 6ff2e7700127b9ec3af52df08c905bc2 255 Gene3D G3DSA:3.40.50.300 15 252 2.5E-62 T 29-03-2018 SMALA_RS02730 6ff2e7700127b9ec3af52df08c905bc2 255 SUPERFAMILY SSF52540 17 233 1.52E-67 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS27045 acb38fdb14a273d8d7beb8f1b84c315e 150 SUPERFAMILY SSF54593 1 140 5.91E-34 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS27045 acb38fdb14a273d8d7beb8f1b84c315e 150 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 122 2.5E-20 T 29-03-2018 SMALA_RS27045 acb38fdb14a273d8d7beb8f1b84c315e 150 Gene3D G3DSA:3.10.180.10 1 141 5.5E-31 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS27045 acb38fdb14a273d8d7beb8f1b84c315e 150 TIGRFAM TIGR03081 metmalonyl_epim: methylmalonyl-CoA epimerase 4 136 1.9E-42 T 29-03-2018 IPR017515 Methylmalonyl-CoA epimerase KEGG: 00280+5.1.99.1|KEGG: 00630+5.1.99.1|KEGG: 00640+5.1.99.1|KEGG: 00720+5.1.99.1|MetaCyc: PWY-5741|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384|MetaCyc: PWY-7854|Reactome: R-HSA-71032 SMALA_RS32255 4de2503ec7b265b2c53c344c6183d4a6 260 Gene3D G3DSA:3.40.50.720 54 257 5.2E-59 T 29-03-2018 SMALA_RS32255 4de2503ec7b265b2c53c344c6183d4a6 260 Gene3D G3DSA:3.40.50.720 6 53 3.9E-12 T 29-03-2018 SMALA_RS32255 4de2503ec7b265b2c53c344c6183d4a6 260 SUPERFAMILY SSF51735 12 252 4.48E-80 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS32255 4de2503ec7b265b2c53c344c6183d4a6 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 4.9E-45 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS32255 4de2503ec7b265b2c53c344c6183d4a6 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 4.9E-45 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS32255 4de2503ec7b265b2c53c344c6183d4a6 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 4.9E-45 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS32255 4de2503ec7b265b2c53c344c6183d4a6 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 4.9E-45 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS32255 4de2503ec7b265b2c53c344c6183d4a6 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 4.9E-45 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS32255 4de2503ec7b265b2c53c344c6183d4a6 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 4.9E-45 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS32255 4de2503ec7b265b2c53c344c6183d4a6 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 1.3E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS32255 4de2503ec7b265b2c53c344c6183d4a6 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 1.3E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS32255 4de2503ec7b265b2c53c344c6183d4a6 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 1.3E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS32255 4de2503ec7b265b2c53c344c6183d4a6 260 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 19 252 3.3E-70 T 29-03-2018 SMALA_RS28710 48d3684be1a85a083bf82bbc95027b9a 232 Gene3D G3DSA:3.40.640.10 5 100 4.7E-17 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS28710 48d3684be1a85a083bf82bbc95027b9a 232 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 111 220 1.4E-11 T 29-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase SMALA_RS28710 48d3684be1a85a083bf82bbc95027b9a 232 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 5 99 1.1E-27 T 29-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase SMALA_RS28710 48d3684be1a85a083bf82bbc95027b9a 232 Gene3D G3DSA:3.90.1150.10 109 225 1.4E-20 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS28710 48d3684be1a85a083bf82bbc95027b9a 232 SUPERFAMILY SSF53383 14 222 3.86E-36 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS07980 c0465b6732c13f834afd7b1a0abbd5a9 132 SUPERFAMILY SSF55620 2 129 1.67E-27 T 29-03-2018 SMALA_RS07980 c0465b6732c13f834afd7b1a0abbd5a9 132 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 4 130 1.6E-20 T 29-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 SMALA_RS07980 c0465b6732c13f834afd7b1a0abbd5a9 132 Gene3D G3DSA:3.30.479.10 1 132 2.8E-26 T 29-03-2018 SMALA_RS03620 aa68573423aeca508f910e601d44d757 474 Gene3D G3DSA:1.25.10.10 10 465 3.5E-4 T 29-03-2018 IPR011989 Armadillo-like helical SMALA_RS21210 caf9e6596d2d009ab02dfdb5fa476c4d 695 SUPERFAMILY SSF56235 34 190 3.09E-12 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SMALA_RS21210 caf9e6596d2d009ab02dfdb5fa476c4d 695 Gene3D G3DSA:3.40.50.620 190 670 2.9E-34 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS21210 caf9e6596d2d009ab02dfdb5fa476c4d 695 SUPERFAMILY SSF52402 256 399 1.42E-8 T 29-03-2018 SMALA_RS21210 caf9e6596d2d009ab02dfdb5fa476c4d 695 SUPERFAMILY SSF52402 202 225 1.42E-8 T 29-03-2018 SMALA_RS21210 caf9e6596d2d009ab02dfdb5fa476c4d 695 SUPERFAMILY SSF52402 523 636 1.42E-8 T 29-03-2018 SMALA_RS21210 caf9e6596d2d009ab02dfdb5fa476c4d 695 Pfam PF00733 Asparagine synthase 260 664 3.8E-8 T 29-03-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 SMALA_RS07530 1bb97402fc5068b63745ead8510d0b52 310 SUPERFAMILY SSF54001 178 292 1.08E-33 T 29-03-2018 SMALA_RS07530 1bb97402fc5068b63745ead8510d0b52 310 Gene3D G3DSA:3.90.1720.10 189 303 1.0E-31 T 29-03-2018 SMALA_RS07530 1bb97402fc5068b63745ead8510d0b52 310 Pfam PF00877 NlpC/P60 family 197 287 1.2E-20 T 29-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain SMALA_RS07530 1bb97402fc5068b63745ead8510d0b52 310 Pfam PF01464 Transglycosylase SLT domain 64 172 2.6E-9 T 29-03-2018 IPR008258 Transglycosylase SLT domain 1 SMALA_RS07530 1bb97402fc5068b63745ead8510d0b52 310 SUPERFAMILY SSF53955 48 175 2.25E-30 T 29-03-2018 IPR023346 Lysozyme-like domain SMALA_RS07530 1bb97402fc5068b63745ead8510d0b52 310 Gene3D G3DSA:1.10.530.10 45 188 9.8E-30 T 29-03-2018 SMALA_RS08175 0feb05576d0da678c773b8cc66ebac2c 717 SUPERFAMILY SSF52317 1 187 1.6E-51 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS08175 0feb05576d0da678c773b8cc66ebac2c 717 Pfam PF04715 Anthranilate synthase component I, N terminal region 247 377 3.4E-14 T 29-03-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 SMALA_RS08175 0feb05576d0da678c773b8cc66ebac2c 717 PRINTS PR00097 Anthranilate synthase component II signature 77 88 3.3E-30 T 29-03-2018 SMALA_RS08175 0feb05576d0da678c773b8cc66ebac2c 717 PRINTS PR00097 Anthranilate synthase component II signature 165 178 3.3E-30 T 29-03-2018 SMALA_RS08175 0feb05576d0da678c773b8cc66ebac2c 717 PRINTS PR00097 Anthranilate synthase component II signature 122 134 3.3E-30 T 29-03-2018 SMALA_RS08175 0feb05576d0da678c773b8cc66ebac2c 717 PRINTS PR00097 Anthranilate synthase component II signature 49 58 3.3E-30 T 29-03-2018 SMALA_RS08175 0feb05576d0da678c773b8cc66ebac2c 717 PRINTS PR00097 Anthranilate synthase component II signature 3 17 3.3E-30 T 29-03-2018 SMALA_RS08175 0feb05576d0da678c773b8cc66ebac2c 717 PRINTS PR00097 Anthranilate synthase component II signature 102 110 3.3E-30 T 29-03-2018 SMALA_RS08175 0feb05576d0da678c773b8cc66ebac2c 717 TIGRFAM TIGR00553 pabB: aminodeoxychorismate synthase, component I 332 689 1.0E-114 T 29-03-2018 IPR005802 Para-aminobenzoate synthase, component I GO:0009396 KEGG: 00790+2.6.1.85|MetaCyc: PWY-6543 SMALA_RS08175 0feb05576d0da678c773b8cc66ebac2c 717 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 46 60 7.8E-7 T 29-03-2018 SMALA_RS08175 0feb05576d0da678c773b8cc66ebac2c 717 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 77 93 7.8E-7 T 29-03-2018 SMALA_RS08175 0feb05576d0da678c773b8cc66ebac2c 717 Pfam PF00425 chorismate binding enzyme 431 685 7.2E-89 T 29-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal SMALA_RS08175 0feb05576d0da678c773b8cc66ebac2c 717 PRINTS PR00096 Glutamine amidotransferase superfamily signature 49 58 1.1E-12 T 29-03-2018 SMALA_RS08175 0feb05576d0da678c773b8cc66ebac2c 717 PRINTS PR00096 Glutamine amidotransferase superfamily signature 165 178 1.1E-12 T 29-03-2018 SMALA_RS08175 0feb05576d0da678c773b8cc66ebac2c 717 PRINTS PR00096 Glutamine amidotransferase superfamily signature 77 88 1.1E-12 T 29-03-2018 SMALA_RS08175 0feb05576d0da678c773b8cc66ebac2c 717 Gene3D G3DSA:3.60.120.10 227 697 1.8E-150 T 29-03-2018 IPR005801 ADC synthase GO:0009058 SMALA_RS08175 0feb05576d0da678c773b8cc66ebac2c 717 Gene3D G3DSA:3.40.50.880 1 192 3.1E-54 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS08175 0feb05576d0da678c773b8cc66ebac2c 717 SUPERFAMILY SSF56322 228 695 1.31E-127 T 29-03-2018 IPR005801 ADC synthase GO:0009058 SMALA_RS08175 0feb05576d0da678c773b8cc66ebac2c 717 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 4 186 5.0E-49 T 29-03-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 SMALA_RS08175 0feb05576d0da678c773b8cc66ebac2c 717 Pfam PF00117 Glutamine amidotransferase class-I 5 185 4.4E-43 T 29-03-2018 IPR017926 Glutamine amidotransferase SMALA_RS34465 11b9b917964d311e17e9242d62a1d65c 218 Pfam PF00857 Isochorismatase family 20 168 1.2E-25 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SMALA_RS34465 11b9b917964d311e17e9242d62a1d65c 218 SUPERFAMILY SSF52499 12 206 3.92E-45 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SMALA_RS34465 11b9b917964d311e17e9242d62a1d65c 218 Gene3D G3DSA:3.40.50.850 6 204 8.5E-32 T 29-03-2018 SMALA_RS17670 a09630c96a51c222c486bc3b3bf21cde 163 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 44 59 - T 29-03-2018 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 SMALA_RS17670 a09630c96a51c222c486bc3b3bf21cde 163 SUPERFAMILY SSF69765 10 162 1.15E-47 T 29-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 SMALA_RS17670 a09630c96a51c222c486bc3b3bf21cde 163 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 9 162 29.887 T 29-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 SMALA_RS17670 a09630c96a51c222c486bc3b3bf21cde 163 Gene3D G3DSA:3.30.1330.50 3 163 1.4E-56 T 29-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 SMALA_RS17670 a09630c96a51c222c486bc3b3bf21cde 163 Pfam PF02542 YgbB family 11 160 1.5E-44 T 29-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 SMALA_RS17670 a09630c96a51c222c486bc3b3bf21cde 163 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 11 161 2.2E-42 T 29-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 SMALA_RS04840 09d6e4d9de3cb3acd5575f0cf68d4d5d 679 Gene3D G3DSA:3.90.660.10 81 213 2.5E-14 T 29-03-2018 SMALA_RS04840 09d6e4d9de3cb3acd5575f0cf68d4d5d 679 Gene3D G3DSA:3.90.660.10 331 618 6.9E-36 T 29-03-2018 SMALA_RS04840 09d6e4d9de3cb3acd5575f0cf68d4d5d 679 SUPERFAMILY SSF54373 523 610 2.03E-19 T 29-03-2018 SMALA_RS04840 09d6e4d9de3cb3acd5575f0cf68d4d5d 679 Pfam PF01593 Flavin containing amine oxidoreductase 526 662 9.7E-20 T 29-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 SMALA_RS04840 09d6e4d9de3cb3acd5575f0cf68d4d5d 679 Pfam PF01593 Flavin containing amine oxidoreductase 67 448 3.0E-29 T 29-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 SMALA_RS04840 09d6e4d9de3cb3acd5575f0cf68d4d5d 679 Gene3D G3DSA:1.10.405.10 214 318 3.4E-20 T 29-03-2018 SMALA_RS04840 09d6e4d9de3cb3acd5575f0cf68d4d5d 679 SUPERFAMILY SSF51905 602 664 3.37E-50 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS04840 09d6e4d9de3cb3acd5575f0cf68d4d5d 679 SUPERFAMILY SSF51905 56 445 3.37E-50 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS37915 9829b623eaa011c4b354ad622e3b0714 281 Pfam PF00795 Carbon-nitrogen hydrolase 23 256 1.7E-44 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMALA_RS37915 9829b623eaa011c4b354ad622e3b0714 281 SUPERFAMILY SSF56317 14 270 3.14E-68 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMALA_RS37915 9829b623eaa011c4b354ad622e3b0714 281 Gene3D G3DSA:3.60.110.10 2 273 1.0E-71 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMALA_RS37915 9829b623eaa011c4b354ad622e3b0714 281 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 151 171 - T 29-03-2018 IPR001110 Uncharacterised protein family UPF0012, conserved site SMALA_RS30265 4d32cd09f17603b9fc7cb90731833e14 182 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 7 172 2.8E-58 T 29-03-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 SMALA_RS30265 4d32cd09f17603b9fc7cb90731833e14 182 Gene3D G3DSA:3.40.50.300 4 182 1.4E-40 T 29-03-2018 SMALA_RS30265 4d32cd09f17603b9fc7cb90731833e14 182 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 6 180 34.034 T 29-03-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 SMALA_RS30265 4d32cd09f17603b9fc7cb90731833e14 182 SUPERFAMILY SSF52540 8 179 2.58E-34 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS30265 4d32cd09f17603b9fc7cb90731833e14 182 Pfam PF01583 Adenylylsulphate kinase 8 164 7.8E-60 T 29-03-2018 SMALA_RS03020 6b33d778847e9a87b4f588d12e7645af 101 Pfam PF00253 Ribosomal protein S14p/S29e 48 100 2.0E-23 T 29-03-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS03020 6b33d778847e9a87b4f588d12e7645af 101 Hamap MF_00537 30S ribosomal protein S14 [rpsN]. 1 101 26.439 T 29-03-2018 IPR023036 Ribosomal protein S14, bacterial/plastid SMALA_RS03020 6b33d778847e9a87b4f588d12e7645af 101 Gene3D G3DSA:4.10.830.10 1 101 2.1E-31 T 29-03-2018 SMALA_RS03020 6b33d778847e9a87b4f588d12e7645af 101 SUPERFAMILY SSF57716 2 101 3.64E-34 T 29-03-2018 SMALA_RS05565 935e853df3732b712fd1427706006f32 483 SUPERFAMILY SSF75304 5 476 6.02E-116 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMALA_RS05565 935e853df3732b712fd1427706006f32 483 ProSitePatterns PS00571 Amidases signature. 145 176 - T 29-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 SMALA_RS05565 935e853df3732b712fd1427706006f32 483 Pfam PF01425 Amidase 47 455 5.1E-88 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMALA_RS05565 935e853df3732b712fd1427706006f32 483 Gene3D G3DSA:3.90.1300.10 2 481 2.7E-121 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMALA_RS10165 22b26f1bcc81c0e168ca01501df15210 194 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 83 91 1.0E-14 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 SMALA_RS10165 22b26f1bcc81c0e168ca01501df15210 194 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 125 140 1.0E-14 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 SMALA_RS10165 22b26f1bcc81c0e168ca01501df15210 194 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 163 179 1.0E-14 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 SMALA_RS10165 22b26f1bcc81c0e168ca01501df15210 194 ProSitePatterns PS00855 Signal peptidases II signature. 128 140 - T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 SMALA_RS10165 22b26f1bcc81c0e168ca01501df15210 194 Pfam PF01252 Signal peptidase (SPase) II 45 182 2.5E-29 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 SMALA_RS10165 22b26f1bcc81c0e168ca01501df15210 194 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 36 188 14.418 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 SMALA_RS00725 cb1aaa3aecc796156ac8f23b868d9b2d 396 SUPERFAMILY SSF54373 181 283 1.22E-27 T 29-03-2018 SMALA_RS00725 cb1aaa3aecc796156ac8f23b868d9b2d 396 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 307 323 4.0E-20 T 29-03-2018 SMALA_RS00725 cb1aaa3aecc796156ac8f23b868d9b2d 396 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 4.0E-20 T 29-03-2018 SMALA_RS00725 cb1aaa3aecc796156ac8f23b868d9b2d 396 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 292 307 4.0E-20 T 29-03-2018 SMALA_RS00725 cb1aaa3aecc796156ac8f23b868d9b2d 396 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 155 170 4.0E-20 T 29-03-2018 SMALA_RS00725 cb1aaa3aecc796156ac8f23b868d9b2d 396 SUPERFAMILY SSF51905 2 176 5.59E-58 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS00725 cb1aaa3aecc796156ac8f23b868d9b2d 396 SUPERFAMILY SSF51905 279 375 5.59E-58 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS00725 cb1aaa3aecc796156ac8f23b868d9b2d 396 Gene3D G3DSA:3.50.50.60 1 382 9.3E-45 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS00725 cb1aaa3aecc796156ac8f23b868d9b2d 396 Pfam PF01494 FAD binding domain 289 353 1.0E-10 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 SMALA_RS00725 cb1aaa3aecc796156ac8f23b868d9b2d 396 Pfam PF01494 FAD binding domain 2 174 2.4E-16 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 SMALA_RS03210 01fdc830d90bf409c88557d0dac22131 253 Gene3D G3DSA:3.40.50.720 9 252 1.2E-66 T 29-03-2018 SMALA_RS03210 01fdc830d90bf409c88557d0dac22131 253 SUPERFAMILY SSF51735 9 248 9.05E-77 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS03210 01fdc830d90bf409c88557d0dac22131 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 3.1E-42 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS03210 01fdc830d90bf409c88557d0dac22131 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 3.1E-42 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS03210 01fdc830d90bf409c88557d0dac22131 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 3.1E-42 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS03210 01fdc830d90bf409c88557d0dac22131 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 3.1E-42 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS03210 01fdc830d90bf409c88557d0dac22131 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 3.1E-42 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS03210 01fdc830d90bf409c88557d0dac22131 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 3.1E-42 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS03210 01fdc830d90bf409c88557d0dac22131 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 2.5E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS03210 01fdc830d90bf409c88557d0dac22131 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 2.5E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS03210 01fdc830d90bf409c88557d0dac22131 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 2.5E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS03210 01fdc830d90bf409c88557d0dac22131 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 246 4.5E-57 T 29-03-2018 SMALA_RS03210 01fdc830d90bf409c88557d0dac22131 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMALA_RS03210 01fdc830d90bf409c88557d0dac22131 253 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 10 187 0.0091 T 29-03-2018 SMALA_RS40810 f7c4e1ced825f2f6c70c70ba3c9fb0d0 62 Pfam PF01979 Amidohydrolase family 6 59 1.8E-5 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 SMALA_RS40810 f7c4e1ced825f2f6c70c70ba3c9fb0d0 62 SUPERFAMILY SSF51338 6 59 1.11E-8 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS40810 f7c4e1ced825f2f6c70c70ba3c9fb0d0 62 Gene3D G3DSA:2.30.40.10 3 60 2.0E-11 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS38925 d991b504ad31d3d42698a6ceeecf8fde 187 SUPERFAMILY SSF54427 12 144 1.97E-24 T 29-03-2018 IPR032710 NTF2-like domain SMALA_RS38925 d991b504ad31d3d42698a6ceeecf8fde 187 Gene3D G3DSA:3.10.450.50 8 146 8.4E-21 T 29-03-2018 SMALA_RS38925 d991b504ad31d3d42698a6ceeecf8fde 187 Pfam PF07366 SnoaL-like polyketide cyclase 19 144 6.4E-14 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain SMALA_RS08675 52ec2b0ee6ce46b2d99dea5d9a04d328 120 ProDom PD031888 MUTASE CHORISMATE AROH THE CLASS ISOMERASE TRANSCRIPTION BIOSYNTHESIS CM 3D-STRUCTURE 9 118 7.0E-46 T 29-03-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 SMALA_RS08675 52ec2b0ee6ce46b2d99dea5d9a04d328 120 PIRSF PIRSF005965 1 120 4.3E-42 T 29-03-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 SMALA_RS08675 52ec2b0ee6ce46b2d99dea5d9a04d328 120 Pfam PF07736 Chorismate mutase type I 3 118 9.4E-42 T 29-03-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 SMALA_RS08675 52ec2b0ee6ce46b2d99dea5d9a04d328 120 SUPERFAMILY SSF55298 2 118 8.63E-41 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SMALA_RS08675 52ec2b0ee6ce46b2d99dea5d9a04d328 120 Gene3D G3DSA:3.30.1330.40 3 119 4.2E-44 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SMALA_RS08675 52ec2b0ee6ce46b2d99dea5d9a04d328 120 TIGRFAM TIGR01796 CM_mono_aroH: chorismate mutase 3 118 3.4E-48 T 29-03-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 SMALA_RS43280 f608acb9123160aa0d72e195e4f37026 504 Gene3D G3DSA:3.40.50.300 95 500 1.1E-17 T 29-03-2018 SMALA_RS43280 f608acb9123160aa0d72e195e4f37026 504 SUPERFAMILY SSF52540 73 497 8.15E-31 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS26495 7326b60411022b64b2d0989e70a76dc4 258 Gene3D G3DSA:3.30.70.100 11 121 5.0E-19 T 29-03-2018 SMALA_RS26495 7326b60411022b64b2d0989e70a76dc4 258 Gene3D G3DSA:3.30.70.100 123 243 3.7E-11 T 29-03-2018 SMALA_RS26495 7326b60411022b64b2d0989e70a76dc4 258 SUPERFAMILY SSF54909 28 92 1.32E-6 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel SMALA_RS26495 7326b60411022b64b2d0989e70a76dc4 258 Pfam PF03992 Antibiotic biosynthesis monooxygenase 133 207 3.4E-6 T 29-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain SMALA_RS15020 166cc10f66bbd13a95ab6208d0d1e83e 421 Pfam PF02378 Phosphotransferase system, EIIC 27 340 5.3E-75 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 SMALA_RS06100 ea90682318a845d8fcddae28d893101e 322 Pfam PF05448 Acetyl xylan esterase (AXE1) 1 318 6.8E-123 T 29-03-2018 IPR008391 Acetyl xylan esterase SMALA_RS06100 ea90682318a845d8fcddae28d893101e 322 SUPERFAMILY SSF53474 4 317 4.63E-28 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS06100 ea90682318a845d8fcddae28d893101e 322 Gene3D G3DSA:3.40.50.1820 1 320 1.5E-33 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS06940 f4fe9378821862af74f4290549860aea 389 Gene3D G3DSA:3.90.180.10 1 174 6.2E-42 T 29-03-2018 SMALA_RS06940 f4fe9378821862af74f4290549860aea 389 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 137 1.6E-26 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS06940 f4fe9378821862af74f4290549860aea 389 SUPERFAMILY SSF51735 154 347 1.12E-58 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS06940 f4fe9378821862af74f4290549860aea 389 Gene3D G3DSA:3.40.50.720 175 330 5.5E-17 T 29-03-2018 SMALA_RS06940 f4fe9378821862af74f4290549860aea 389 Pfam PF00107 Zinc-binding dehydrogenase 188 326 1.6E-10 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMALA_RS06940 f4fe9378821862af74f4290549860aea 389 SUPERFAMILY SSF50129 1 188 1.22E-57 T 29-03-2018 IPR011032 GroES-like SMALA_RS06940 f4fe9378821862af74f4290549860aea 389 Pfam PF13823 Alcohol dehydrogenase GroES-associated 1 23 2.1E-8 T 29-03-2018 IPR027399 Alcohol dehydrogenase GroES-associated SMALA_RS30185 ed42bcfcdf0c161978ea8d186c9f3cdc 355 Pfam PF01066 CDP-alcohol phosphatidyltransferase 46 112 4.2E-10 T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 SMALA_RS30185 ed42bcfcdf0c161978ea8d186c9f3cdc 355 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 90 112 - T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 SMALA_RS09290 bd1f161f58c3ba244f9b648fe13b809e 326 Pfam PF00248 Aldo/keto reductase family 15 314 5.5E-78 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS09290 bd1f161f58c3ba244f9b648fe13b809e 326 Gene3D G3DSA:3.20.20.100 3 321 6.4E-100 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS09290 bd1f161f58c3ba244f9b648fe13b809e 326 SUPERFAMILY SSF51430 1 321 8.64E-108 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS17785 f5ac910dd6481e9bdc17a192945160bf 516 Gene3D G3DSA:1.20.1250.20 5 203 6.3E-31 T 29-03-2018 SMALA_RS17785 f5ac910dd6481e9bdc17a192945160bf 516 Gene3D G3DSA:1.20.1250.20 215 410 6.8E-23 T 29-03-2018 SMALA_RS17785 f5ac910dd6481e9bdc17a192945160bf 516 Pfam PF07690 Major Facilitator Superfamily 25 251 7.3E-31 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS17785 f5ac910dd6481e9bdc17a192945160bf 516 SUPERFAMILY SSF103473 18 407 4.45E-59 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS11115 de03df3c85c6f977930cb40bcecfef2b 295 Pfam PF00005 ABC transporter 46 191 7.6E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS11115 de03df3c85c6f977930cb40bcecfef2b 295 Gene3D G3DSA:3.40.50.300 26 261 1.9E-56 T 29-03-2018 SMALA_RS11115 de03df3c85c6f977930cb40bcecfef2b 295 SMART SM00382 53 239 4.1E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS11115 de03df3c85c6f977930cb40bcecfef2b 295 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS11115 de03df3c85c6f977930cb40bcecfef2b 295 SUPERFAMILY SSF52540 20 253 9.45E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS23210 12f4df47a3bafe198af1ee2965ee35d6 242 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 4 232 1.7E-59 T 29-03-2018 SMALA_RS23210 12f4df47a3bafe198af1ee2965ee35d6 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 197 217 8.5E-29 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS23210 12f4df47a3bafe198af1ee2965ee35d6 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 70 81 8.5E-29 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS23210 12f4df47a3bafe198af1ee2965ee35d6 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 181 8.5E-29 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS23210 12f4df47a3bafe198af1ee2965ee35d6 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 118 134 8.5E-29 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS23210 12f4df47a3bafe198af1ee2965ee35d6 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 163 8.5E-29 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS23210 12f4df47a3bafe198af1ee2965ee35d6 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 70 81 4.0E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS23210 12f4df47a3bafe198af1ee2965ee35d6 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 144 163 4.0E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS23210 12f4df47a3bafe198af1ee2965ee35d6 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 124 132 4.0E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS23210 12f4df47a3bafe198af1ee2965ee35d6 242 SUPERFAMILY SSF51735 1 234 1.17E-72 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS23210 12f4df47a3bafe198af1ee2965ee35d6 242 Gene3D G3DSA:3.40.50.720 1 242 4.3E-68 T 29-03-2018 SMALA_RS42445 e492e6b55b39be29c3530a4290946934 265 SUPERFAMILY SSF48498 98 232 3.73E-26 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS42445 e492e6b55b39be29c3530a4290946934 265 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 71 4.5E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS42445 e492e6b55b39be29c3530a4290946934 265 Gene3D G3DSA:1.10.10.60 1 46 3.4E-12 T 29-03-2018 SMALA_RS42445 e492e6b55b39be29c3530a4290946934 265 Gene3D G3DSA:1.10.260.40 47 77 1.3E-10 T 29-03-2018 SMALA_RS42445 e492e6b55b39be29c3530a4290946934 265 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 7.0E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS42445 e492e6b55b39be29c3530a4290946934 265 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 7.0E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS42445 e492e6b55b39be29c3530a4290946934 265 SUPERFAMILY SSF46689 14 87 1.4E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS42445 e492e6b55b39be29c3530a4290946934 265 Gene3D G3DSA:1.10.357.10 78 238 1.3E-30 T 29-03-2018 SMALA_RS15940 7b7eac971c5429a07c7adc24ad8238c3 182 Pfam PF03061 Thioesterase superfamily 37 107 4.4E-19 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 SMALA_RS15940 7b7eac971c5429a07c7adc24ad8238c3 182 Gene3D G3DSA:3.10.129.10 2 168 5.1E-53 T 29-03-2018 SMALA_RS15940 7b7eac971c5429a07c7adc24ad8238c3 182 SUPERFAMILY SSF54637 17 171 2.2E-44 T 29-03-2018 IPR029069 HotDog domain SMALA_RS23840 8faea70dfee8f895baa61d19f5f64af7 190 SUPERFAMILY SSF48498 75 185 5.64E-18 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS23840 8faea70dfee8f895baa61d19f5f64af7 190 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 58 2.7E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS23840 8faea70dfee8f895baa61d19f5f64af7 190 SUPERFAMILY SSF46689 2 70 1.8E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS23840 8faea70dfee8f895baa61d19f5f64af7 190 Gene3D G3DSA:1.10.357.10 61 190 1.6E-17 T 29-03-2018 SMALA_RS23840 8faea70dfee8f895baa61d19f5f64af7 190 Pfam PF16859 Bacterial transcriptional repressor C-terminal 72 182 3.9E-28 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS23840 8faea70dfee8f895baa61d19f5f64af7 190 Gene3D G3DSA:1.10.10.60 1 60 2.6E-14 T 29-03-2018 SMALA_RS39320 7da4712093ddf9ed2e92ad35db53a52d 190 Gene3D G3DSA:1.10.357.10 2 190 3.2E-42 T 29-03-2018 SMALA_RS39320 7da4712093ddf9ed2e92ad35db53a52d 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 1.0E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS39320 7da4712093ddf9ed2e92ad35db53a52d 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 1.0E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS39320 7da4712093ddf9ed2e92ad35db53a52d 190 SUPERFAMILY SSF48498 85 189 5.34E-13 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS39320 7da4712093ddf9ed2e92ad35db53a52d 190 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 65 6.0E-14 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS39320 7da4712093ddf9ed2e92ad35db53a52d 190 SUPERFAMILY SSF46689 7 87 1.4E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS30730 831c1949869e6bffc0ccef676b247847 627 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 522 539 1.1E-67 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 SMALA_RS30730 831c1949869e6bffc0ccef676b247847 627 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 185 204 1.1E-67 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 SMALA_RS30730 831c1949869e6bffc0ccef676b247847 627 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 324 343 1.1E-67 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 SMALA_RS30730 831c1949869e6bffc0ccef676b247847 627 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 462 480 1.1E-67 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 SMALA_RS30730 831c1949869e6bffc0ccef676b247847 627 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 92 117 1.1E-67 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 SMALA_RS30730 831c1949869e6bffc0ccef676b247847 627 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 167 185 1.1E-67 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 SMALA_RS30730 831c1949869e6bffc0ccef676b247847 627 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 498 513 1.1E-67 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 SMALA_RS30730 831c1949869e6bffc0ccef676b247847 627 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 438 456 1.1E-67 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 SMALA_RS30730 831c1949869e6bffc0ccef676b247847 627 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 294 310 1.1E-67 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 SMALA_RS30730 831c1949869e6bffc0ccef676b247847 627 TIGRFAM TIGR00066 g_glut_trans: gamma-glutamyltransferase 72 606 2.4E-126 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 SMALA_RS30730 831c1949869e6bffc0ccef676b247847 627 SUPERFAMILY SSF56235 63 617 1.74E-154 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SMALA_RS30730 831c1949869e6bffc0ccef676b247847 627 Pfam PF01019 Gamma-glutamyltranspeptidase 85 615 1.7E-153 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 SMALA_RS02675 237af65257cb56211fbb686634780019 624 Gene3D G3DSA:2.60.40.10 43 133 1.3E-23 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS02675 237af65257cb56211fbb686634780019 624 Pfam PF02927 Cellulase N-terminal ig-like domain 44 126 1.1E-24 T 29-03-2018 IPR004197 Cellulase, Ig-like domain GO:0005975|GO:0008810 SMALA_RS02675 237af65257cb56211fbb686634780019 624 ProSitePatterns PS00698 Glycosyl hydrolases family 9 active sites signature 2. 584 602 - T 29-03-2018 IPR033126 Glycosyl hydrolases family 9, Asp/Glu active sites KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 SMALA_RS02675 237af65257cb56211fbb686634780019 624 Gene3D G3DSA:1.50.10.10 135 614 1.3E-128 T 29-03-2018 SMALA_RS02675 237af65257cb56211fbb686634780019 624 SUPERFAMILY SSF81296 46 134 7.7E-22 T 29-03-2018 IPR014756 Immunoglobulin E-set SMALA_RS02675 237af65257cb56211fbb686634780019 624 SUPERFAMILY SSF48208 136 612 7.78E-129 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 SMALA_RS02675 237af65257cb56211fbb686634780019 624 Pfam PF00759 Glycosyl hydrolase family 9 137 607 1.5E-104 T 29-03-2018 IPR001701 Glycoside hydrolase family 9 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 SMALA_RS25445 9e4aa9617b7e8fc5ae9f7adebfcbff4d 360 Gene3D G3DSA:3.90.180.10 4 157 3.9E-43 T 29-03-2018 SMALA_RS25445 9e4aa9617b7e8fc5ae9f7adebfcbff4d 360 Pfam PF00107 Zinc-binding dehydrogenase 176 307 3.1E-9 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMALA_RS25445 9e4aa9617b7e8fc5ae9f7adebfcbff4d 360 SUPERFAMILY SSF50129 5 174 1.98E-45 T 29-03-2018 IPR011032 GroES-like SMALA_RS25445 9e4aa9617b7e8fc5ae9f7adebfcbff4d 360 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 134 4.9E-29 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS25445 9e4aa9617b7e8fc5ae9f7adebfcbff4d 360 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 60 74 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 SMALA_RS25445 9e4aa9617b7e8fc5ae9f7adebfcbff4d 360 Gene3D G3DSA:3.40.50.720 158 316 1.6E-23 T 29-03-2018 SMALA_RS25445 9e4aa9617b7e8fc5ae9f7adebfcbff4d 360 SMART SM00829 2 335 6.1E-5 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS25445 9e4aa9617b7e8fc5ae9f7adebfcbff4d 360 SUPERFAMILY SSF51735 142 319 4.9E-21 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS24680 5404c4e53b57f9f27725c803ac8b2b4d 237 SUPERFAMILY SSF53955 165 231 3.38E-10 T 29-03-2018 IPR023346 Lysozyme-like domain SMALA_RS24680 5404c4e53b57f9f27725c803ac8b2b4d 237 Pfam PF01464 Transglycosylase SLT domain 161 225 6.8E-7 T 29-03-2018 IPR008258 Transglycosylase SLT domain 1 SMALA_RS24680 5404c4e53b57f9f27725c803ac8b2b4d 237 Gene3D G3DSA:1.10.530.10 40 235 3.0E-16 T 29-03-2018 SMALA_RS12585 3134925994cbc5f1dc00772913417aa6 504 Pfam PF13520 Amino acid permease 24 451 2.0E-50 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMALA_RS12585 3134925994cbc5f1dc00772913417aa6 504 PIRSF PIRSF006060 3 493 4.7E-84 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMALA_RS14095 e0bc5bfda0b202e18dce89000e5e2a04 642 SUPERFAMILY SSF51445 67 455 1.26E-105 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS14095 e0bc5bfda0b202e18dce89000e5e2a04 642 SUPERFAMILY SSF52279 458 642 6.67E-13 T 29-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 SMALA_RS14095 e0bc5bfda0b202e18dce89000e5e2a04 642 Gene3D G3DSA:3.40.50.1700 445 628 7.0E-20 T 29-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 SMALA_RS14095 e0bc5bfda0b202e18dce89000e5e2a04 642 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 340 357 - T 29-03-2018 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 SMALA_RS14095 e0bc5bfda0b202e18dce89000e5e2a04 642 Gene3D G3DSA:3.20.20.300 62 444 1.3E-104 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SMALA_RS14095 e0bc5bfda0b202e18dce89000e5e2a04 642 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 458 642 4.9E-14 T 29-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 SMALA_RS14095 e0bc5bfda0b202e18dce89000e5e2a04 642 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 79 419 4.3E-111 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SMALA_RS31520 b41e95fdace6668d4074ff570eb585f6 242 SUPERFAMILY SSF51735 19 224 6.23E-36 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS31520 b41e95fdace6668d4074ff570eb585f6 242 Gene3D G3DSA:3.40.50.720 19 225 7.6E-21 T 29-03-2018 SMALA_RS31520 b41e95fdace6668d4074ff570eb585f6 242 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 20 111 2.4E-16 T 29-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal SMALA_RS31520 b41e95fdace6668d4074ff570eb585f6 242 TIGRFAM TIGR01915 npdG: NADPH-dependent F420 reductase 20 226 1.4E-54 T 29-03-2018 IPR010185 NADPH-dependent F420 reductase GO:0006740|GO:0016651|GO:0050661|GO:0055114|GO:0070967 SMALA_RS15300 99acd75bcdece58738031c550268e434 267 Gene3D G3DSA:3.20.20.370 55 265 2.8E-45 T 29-03-2018 SMALA_RS15300 99acd75bcdece58738031c550268e434 267 SUPERFAMILY SSF88713 76 262 5.44E-51 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 SMALA_RS15300 99acd75bcdece58738031c550268e434 267 Pfam PF01522 Polysaccharide deacetylase 77 199 3.1E-27 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 SMALA_RS26145 7a84435deebe4bf316a91d21cc1b8940 264 SUPERFAMILY SSF56655 3 263 3.53E-75 T 29-03-2018 SMALA_RS26145 7a84435deebe4bf316a91d21cc1b8940 264 Gene3D G3DSA:3.40.190.80 162 264 9.9E-24 T 29-03-2018 SMALA_RS26145 7a84435deebe4bf316a91d21cc1b8940 264 TIGRFAM TIGR02067 his_9_HisN: histidinol-phosphatase 8 262 1.8E-90 T 29-03-2018 IPR011809 Histidinol-phosphate phosphatase, putative, inositol monophosphatase GO:0004401 KEGG: 00340+3.1.3.15 SMALA_RS26145 7a84435deebe4bf316a91d21cc1b8940 264 PRINTS PR00377 Inositol monophosphatase superfamily signature 81 97 9.5E-22 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 SMALA_RS26145 7a84435deebe4bf316a91d21cc1b8940 264 PRINTS PR00377 Inositol monophosphatase superfamily signature 40 60 9.5E-22 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 SMALA_RS26145 7a84435deebe4bf316a91d21cc1b8940 264 PRINTS PR00377 Inositol monophosphatase superfamily signature 62 78 9.5E-22 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 SMALA_RS26145 7a84435deebe4bf316a91d21cc1b8940 264 PRINTS PR00377 Inositol monophosphatase superfamily signature 214 238 9.5E-22 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 SMALA_RS26145 7a84435deebe4bf316a91d21cc1b8940 264 Gene3D G3DSA:3.30.540.10 76 161 4.7E-28 T 29-03-2018 SMALA_RS26145 7a84435deebe4bf316a91d21cc1b8940 264 Gene3D G3DSA:3.30.540.10 2 75 2.3E-15 T 29-03-2018 SMALA_RS26145 7a84435deebe4bf316a91d21cc1b8940 264 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 81 94 - T 29-03-2018 IPR020583 Inositol monophosphatase, metal-binding site SMALA_RS26145 7a84435deebe4bf316a91d21cc1b8940 264 Pfam PF00459 Inositol monophosphatase family 10 239 3.9E-47 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 SMALA_RS34390 99e35b0db2dc57e9d7c094c923a49182 433 Gene3D G3DSA:1.20.1250.20 217 414 1.1E-12 T 29-03-2018 SMALA_RS34390 99e35b0db2dc57e9d7c094c923a49182 433 Pfam PF07690 Major Facilitator Superfamily 26 354 7.4E-28 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS34390 99e35b0db2dc57e9d7c094c923a49182 433 Gene3D G3DSA:1.20.1250.20 6 206 1.1E-20 T 29-03-2018 SMALA_RS34390 99e35b0db2dc57e9d7c094c923a49182 433 SUPERFAMILY SSF103473 16 403 5.49E-38 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS40525 c3ac2fe597b1ec46ef0f31bfb75950ca 308 SMART SM01130 13 304 7.6E-68 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SMALA_RS40525 c3ac2fe597b1ec46ef0f31bfb75950ca 308 Gene3D G3DSA:3.20.20.70 13 307 1.5E-70 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS40525 c3ac2fe597b1ec46ef0f31bfb75950ca 308 Pfam PF00701 Dihydrodipicolinate synthetase family 15 302 9.5E-51 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SMALA_RS40525 c3ac2fe597b1ec46ef0f31bfb75950ca 308 PIRSF PIRSF001365 12 308 6.6E-56 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SMALA_RS40525 c3ac2fe597b1ec46ef0f31bfb75950ca 308 TIGRFAM TIGR03249 KdgD: 5-dehydro-4-deoxyglucarate dehydratase 6 302 1.6E-126 T 29-03-2018 IPR017655 5-dehydro-4-deoxyglucarate dehydratase GO:0016052|GO:0047448 KEGG: 00053+4.2.1.41|MetaCyc: PWY-6486|MetaCyc: PWY-6497|MetaCyc: PWY-6499|MetaCyc: PWY-6501 SMALA_RS40525 c3ac2fe597b1ec46ef0f31bfb75950ca 308 SUPERFAMILY SSF51569 15 302 3.14E-66 T 29-03-2018 SMALA_RS40525 c3ac2fe597b1ec46ef0f31bfb75950ca 308 Hamap MF_00694 Probable 5-dehydro-4-deoxyglucarate dehydratase. 13 304 42.628 T 29-03-2018 IPR017655 5-dehydro-4-deoxyglucarate dehydratase GO:0016052|GO:0047448 KEGG: 00053+4.2.1.41|MetaCyc: PWY-6486|MetaCyc: PWY-6497|MetaCyc: PWY-6499|MetaCyc: PWY-6501 SMALA_RS03675 d505dfad579809c0c3dc0b93adea032f 355 SUPERFAMILY SSF53901 4 117 8.22E-18 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS03675 d505dfad579809c0c3dc0b93adea032f 355 SUPERFAMILY SSF53901 177 335 8.22E-18 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS03675 d505dfad579809c0c3dc0b93adea032f 355 PIRSF PIRSF000429 1 339 1.5E-12 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 SMALA_RS03675 d505dfad579809c0c3dc0b93adea032f 355 Gene3D G3DSA:3.40.47.10 1 216 7.3E-14 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS03675 d505dfad579809c0c3dc0b93adea032f 355 Gene3D G3DSA:3.40.47.10 217 343 9.1E-7 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS03790 f78176cd9638708d109f71f3489f2603 453 Pfam PF00067 Cytochrome P450 19 439 4.4E-79 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS03790 f78176cd9638708d109f71f3489f2603 453 SUPERFAMILY SSF48264 18 453 7.6E-105 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS03790 f78176cd9638708d109f71f3489f2603 453 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 395 404 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMALA_RS03790 f78176cd9638708d109f71f3489f2603 453 PRINTS PR00465 E-class P450 group IV signature 257 283 1.8E-21 T 29-03-2018 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS03790 f78176cd9638708d109f71f3489f2603 453 PRINTS PR00465 E-class P450 group IV signature 346 360 1.8E-21 T 29-03-2018 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS03790 f78176cd9638708d109f71f3489f2603 453 PRINTS PR00465 E-class P450 group IV signature 386 402 1.8E-21 T 29-03-2018 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS03790 f78176cd9638708d109f71f3489f2603 453 PRINTS PR00465 E-class P450 group IV signature 14 31 1.8E-21 T 29-03-2018 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS03790 f78176cd9638708d109f71f3489f2603 453 PRINTS PR00465 E-class P450 group IV signature 313 329 1.8E-21 T 29-03-2018 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS03790 f78176cd9638708d109f71f3489f2603 453 PRINTS PR00465 E-class P450 group IV signature 362 380 1.8E-21 T 29-03-2018 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS03790 f78176cd9638708d109f71f3489f2603 453 PRINTS PR00465 E-class P450 group IV signature 402 420 1.8E-21 T 29-03-2018 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS03790 f78176cd9638708d109f71f3489f2603 453 Gene3D G3DSA:1.10.630.10 12 453 4.2E-114 T 29-03-2018 SMALA_RS03790 f78176cd9638708d109f71f3489f2603 453 PRINTS PR00385 P450 superfamily signature 266 283 9.1E-11 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS03790 f78176cd9638708d109f71f3489f2603 453 PRINTS PR00385 P450 superfamily signature 318 329 9.1E-11 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS03790 f78176cd9638708d109f71f3489f2603 453 PRINTS PR00385 P450 superfamily signature 393 402 9.1E-11 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS03790 f78176cd9638708d109f71f3489f2603 453 PRINTS PR00385 P450 superfamily signature 402 413 9.1E-11 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS20620 1f0733ffa4f5dbebf5280d015d39f362 165 Gene3D G3DSA:3.40.50.2020 2 159 1.9E-24 T 29-03-2018 SMALA_RS20620 1f0733ffa4f5dbebf5280d015d39f362 165 SUPERFAMILY SSF53271 8 151 1.33E-25 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like SMALA_RS20620 1f0733ffa4f5dbebf5280d015d39f362 165 Pfam PF00156 Phosphoribosyl transferase domain 13 152 2.0E-22 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 SMALA_RS16010 724daebe10cae1d2d09b50084536810b 255 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 216 251 5.2E-5 T 29-03-2018 SMALA_RS31935 b5b50eff056be1eaadc3294cf4040fe9 485 Pfam PF07690 Major Facilitator Superfamily 25 292 2.2E-28 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS31935 b5b50eff056be1eaadc3294cf4040fe9 485 Gene3D G3DSA:1.20.1250.20 10 208 5.6E-33 T 29-03-2018 SMALA_RS31935 b5b50eff056be1eaadc3294cf4040fe9 485 Gene3D G3DSA:1.20.1250.20 262 458 1.3E-20 T 29-03-2018 SMALA_RS31935 b5b50eff056be1eaadc3294cf4040fe9 485 SUPERFAMILY SSF103473 258 457 2.88E-63 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS31935 b5b50eff056be1eaadc3294cf4040fe9 485 SUPERFAMILY SSF103473 17 208 2.88E-63 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS36925 84d5b92b26f8a9252365dd129961dfa7 497 Gene3D G3DSA:1.20.1250.20 261 489 7.4E-24 T 29-03-2018 SMALA_RS36925 84d5b92b26f8a9252365dd129961dfa7 497 Pfam PF07690 Major Facilitator Superfamily 28 420 1.6E-48 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS36925 84d5b92b26f8a9252365dd129961dfa7 497 Gene3D G3DSA:1.20.1250.20 11 210 1.9E-31 T 29-03-2018 SMALA_RS36925 84d5b92b26f8a9252365dd129961dfa7 497 SUPERFAMILY SSF103473 16 207 4.45E-59 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS36925 84d5b92b26f8a9252365dd129961dfa7 497 SUPERFAMILY SSF103473 257 481 4.45E-59 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS10015 6d73daa852abfd588cb97e07f4fd2d97 287 Pfam PF04794 YdjC-like protein 19 265 2.4E-48 T 29-03-2018 IPR006879 Carbohydrate deacetylase YdjC-like SMALA_RS10015 6d73daa852abfd588cb97e07f4fd2d97 287 Gene3D G3DSA:3.20.20.370 4 281 9.3E-66 T 29-03-2018 SMALA_RS10015 6d73daa852abfd588cb97e07f4fd2d97 287 SUPERFAMILY SSF88713 17 277 1.51E-53 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 SMALA_RS36975 d3223be6d04e78241a26061c3e0e8c2e 335 Gene3D G3DSA:3.90.180.10 5 162 1.5E-44 T 29-03-2018 SMALA_RS36975 d3223be6d04e78241a26061c3e0e8c2e 335 Pfam PF00107 Zinc-binding dehydrogenase 175 296 1.9E-18 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMALA_RS36975 d3223be6d04e78241a26061c3e0e8c2e 335 SMART SM00829 11 333 0.0031 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS36975 d3223be6d04e78241a26061c3e0e8c2e 335 SUPERFAMILY SSF51735 139 301 4.38E-36 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS36975 d3223be6d04e78241a26061c3e0e8c2e 335 Gene3D G3DSA:3.40.50.720 163 281 6.2E-26 T 29-03-2018 SMALA_RS36975 d3223be6d04e78241a26061c3e0e8c2e 335 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 134 3.8E-25 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS36975 d3223be6d04e78241a26061c3e0e8c2e 335 SUPERFAMILY SSF50129 5 173 4.72E-49 T 29-03-2018 IPR011032 GroES-like SMALA_RS36515 4afa13e3f13d2b7e54f8724ffbf97879 202 Gene3D G3DSA:3.40.50.1100 39 200 1.2E-4 T 29-03-2018 SMALA_RS42385 d6ce2d7919ffaebec4ae243c3807dd23 249 Pfam PF00106 short chain dehydrogenase 7 187 7.1E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS42385 d6ce2d7919ffaebec4ae243c3807dd23 249 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMALA_RS42385 d6ce2d7919ffaebec4ae243c3807dd23 249 Gene3D G3DSA:3.40.50.720 1 244 6.9E-40 T 29-03-2018 SMALA_RS42385 d6ce2d7919ffaebec4ae243c3807dd23 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.8E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS42385 d6ce2d7919ffaebec4ae243c3807dd23 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 1.8E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS42385 d6ce2d7919ffaebec4ae243c3807dd23 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 1.8E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS42385 d6ce2d7919ffaebec4ae243c3807dd23 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 1.8E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS42385 d6ce2d7919ffaebec4ae243c3807dd23 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 1.8E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS42385 d6ce2d7919ffaebec4ae243c3807dd23 249 SUPERFAMILY SSF51735 1 214 9.28E-44 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS42690 014cf3cf113247021f222522e5104432 349 Gene3D G3DSA:1.10.1530.10 10 87 2.4E-24 T 29-03-2018 SMALA_RS42690 014cf3cf113247021f222522e5104432 349 SUPERFAMILY SSF89733 9 346 9.55E-104 T 29-03-2018 IPR003767 Malate/L-lactate dehydrogenase-like GO:0008152|GO:0016491|GO:0055114 SMALA_RS42690 014cf3cf113247021f222522e5104432 349 Gene3D G3DSA:3.30.1370.60 88 315 2.7E-82 T 29-03-2018 SMALA_RS42690 014cf3cf113247021f222522e5104432 349 Pfam PF02615 Malate/L-lactate dehydrogenase 12 341 8.3E-110 T 29-03-2018 IPR003767 Malate/L-lactate dehydrogenase-like GO:0008152|GO:0016491|GO:0055114 SMALA_RS04805 ebac7e50c472e34fb46c8eec1a1140bd 274 PIRSF PIRSF000097 1 272 1.2E-92 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMALA_RS04805 ebac7e50c472e34fb46c8eec1a1140bd 274 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 229 244 - T 29-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 SMALA_RS04805 ebac7e50c472e34fb46c8eec1a1140bd 274 SUPERFAMILY SSF51430 7 268 4.19E-102 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS04805 ebac7e50c472e34fb46c8eec1a1140bd 274 Pfam PF00248 Aldo/keto reductase family 23 260 2.7E-56 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS04805 ebac7e50c472e34fb46c8eec1a1140bd 274 PRINTS PR00069 Aldo-keto reductase signature 93 111 8.8E-51 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMALA_RS04805 ebac7e50c472e34fb46c8eec1a1140bd 274 PRINTS PR00069 Aldo-keto reductase signature 159 188 8.8E-51 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMALA_RS04805 ebac7e50c472e34fb46c8eec1a1140bd 274 PRINTS PR00069 Aldo-keto reductase signature 37 61 8.8E-51 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMALA_RS04805 ebac7e50c472e34fb46c8eec1a1140bd 274 PRINTS PR00069 Aldo-keto reductase signature 125 142 8.8E-51 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMALA_RS04805 ebac7e50c472e34fb46c8eec1a1140bd 274 PRINTS PR00069 Aldo-keto reductase signature 196 220 8.8E-51 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMALA_RS04805 ebac7e50c472e34fb46c8eec1a1140bd 274 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 41 58 - T 29-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 SMALA_RS04805 ebac7e50c472e34fb46c8eec1a1140bd 274 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 125 142 - T 29-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 SMALA_RS04805 ebac7e50c472e34fb46c8eec1a1140bd 274 Gene3D G3DSA:3.20.20.100 1 274 1.0E-105 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS37250 55b149d90af07b0860e77249c3f2292a 435 Pfam PF00188 Cysteine-rich secretory protein family 317 432 4.8E-25 T 29-03-2018 IPR014044 CAP domain SMALA_RS37250 55b149d90af07b0860e77249c3f2292a 435 Pfam PF00188 Cysteine-rich secretory protein family 182 296 2.2E-9 T 29-03-2018 IPR014044 CAP domain SMALA_RS37250 55b149d90af07b0860e77249c3f2292a 435 Pfam PF02342 TerD domain 25 153 4.0E-17 T 29-03-2018 IPR003325 TerD domain GO:0006950 SMALA_RS37250 55b149d90af07b0860e77249c3f2292a 435 SUPERFAMILY SSF55797 176 300 5.49E-10 T 29-03-2018 IPR014044 CAP domain SMALA_RS37250 55b149d90af07b0860e77249c3f2292a 435 SUPERFAMILY SSF55797 313 433 3.4E-27 T 29-03-2018 IPR014044 CAP domain SMALA_RS37250 55b149d90af07b0860e77249c3f2292a 435 Gene3D G3DSA:2.60.60.30 14 152 1.5E-26 T 29-03-2018 SMALA_RS37250 55b149d90af07b0860e77249c3f2292a 435 Gene3D G3DSA:3.40.33.10 310 432 3.9E-20 T 29-03-2018 IPR014044 CAP domain SMALA_RS37250 55b149d90af07b0860e77249c3f2292a 435 Gene3D G3DSA:3.40.33.10 172 286 2.5E-8 T 29-03-2018 IPR014044 CAP domain SMALA_RS40330 f82832731ee46f4a7b45c567bb7a9628 455 Gene3D G3DSA:1.20.1250.20 234 455 3.7E-26 T 29-03-2018 SMALA_RS40330 f82832731ee46f4a7b45c567bb7a9628 455 SUPERFAMILY SSF103473 15 447 1.7E-64 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS40330 f82832731ee46f4a7b45c567bb7a9628 455 Pfam PF00083 Sugar (and other) transporter 23 443 2.2E-34 T 29-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 SMALA_RS40330 f82832731ee46f4a7b45c567bb7a9628 455 Gene3D G3DSA:1.20.1250.20 10 233 2.9E-28 T 29-03-2018 SMALA_RS16980 6ce83c2c83e7e2dbb523ba4732119a4b 283 SUPERFAMILY SSF47413 28 79 1.2E-5 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS16980 6ce83c2c83e7e2dbb523ba4732119a4b 283 Pfam PF13560 Helix-turn-helix domain 5 84 8.6E-16 T 29-03-2018 SMALA_RS16980 6ce83c2c83e7e2dbb523ba4732119a4b 283 SMART SM00530 9 81 1.7E-5 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS16980 6ce83c2c83e7e2dbb523ba4732119a4b 283 Gene3D G3DSA:1.10.260.40 2 85 1.3E-12 T 29-03-2018 SMALA_RS02825 7e24a138784831688d14a5fc77e48845 321 Pfam PF13354 Beta-lactamase enzyme family 86 293 8.4E-38 T 29-03-2018 SMALA_RS02825 7e24a138784831688d14a5fc77e48845 321 SUPERFAMILY SSF56601 66 318 2.51E-72 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMALA_RS02825 7e24a138784831688d14a5fc77e48845 321 Gene3D G3DSA:3.40.710.10 64 320 2.7E-34 T 29-03-2018 SMALA_RS02825 7e24a138784831688d14a5fc77e48845 321 ProSitePatterns PS00146 Beta-lactamase class-A active site. 99 114 - T 29-03-2018 IPR023650 Beta-lactamase, class-A active site KEGG: 00311+3.5.2.6 SMALA_RS02825 7e24a138784831688d14a5fc77e48845 321 PRINTS PR00118 Beta-lactamase class A signature 97 114 1.5E-64 T 29-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 SMALA_RS02825 7e24a138784831688d14a5fc77e48845 321 PRINTS PR00118 Beta-lactamase class A signature 137 162 1.5E-64 T 29-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 SMALA_RS02825 7e24a138784831688d14a5fc77e48845 321 PRINTS PR00118 Beta-lactamase class A signature 199 224 1.5E-64 T 29-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 SMALA_RS02825 7e24a138784831688d14a5fc77e48845 321 PRINTS PR00118 Beta-lactamase class A signature 66 90 1.5E-64 T 29-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 SMALA_RS02825 7e24a138784831688d14a5fc77e48845 321 PRINTS PR00118 Beta-lactamase class A signature 173 197 1.5E-64 T 29-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 SMALA_RS02825 7e24a138784831688d14a5fc77e48845 321 PRINTS PR00118 Beta-lactamase class A signature 235 250 1.5E-64 T 29-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 SMALA_RS02825 7e24a138784831688d14a5fc77e48845 321 PRINTS PR00118 Beta-lactamase class A signature 252 267 1.5E-64 T 29-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 SMALA_RS39465 f678b1871ec3e8552ace70b24bfe07e7 313 Gene3D G3DSA:3.40.190.10 101 311 4.2E-10 T 29-03-2018 SMALA_RS39465 f678b1871ec3e8552ace70b24bfe07e7 313 SUPERFAMILY SSF53850 24 303 1.76E-15 T 29-03-2018 SMALA_RS33845 ecd915bd42c2c3be3c50c4eb096fea22 346 Gene3D G3DSA:1.10.3470.10 51 331 2.5E-28 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SMALA_RS33845 ecd915bd42c2c3be3c50c4eb096fea22 346 Pfam PF02653 Branched-chain amino acid transport system / permease component 59 325 5.2E-38 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 SMALA_RS07390 e02b7c293a0b5383d0c7c6e4b879a689 344 Gene3D G3DSA:3.40.50.2300 34 139 1.1E-16 T 29-03-2018 SMALA_RS07390 e02b7c293a0b5383d0c7c6e4b879a689 344 Pfam PF13407 Periplasmic binding protein domain 36 297 6.5E-50 T 29-03-2018 IPR025997 Periplasmic binding protein SMALA_RS07390 e02b7c293a0b5383d0c7c6e4b879a689 344 SUPERFAMILY SSF53822 35 333 1.01E-54 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SMALA_RS07390 e02b7c293a0b5383d0c7c6e4b879a689 344 Gene3D G3DSA:3.40.50.2300 140 340 1.3E-29 T 29-03-2018 SMALA_RS38755 c4a8c29052c37a3881f5fb521c4cbe71 505 PIRSF PIRSF006060 17 483 2.8E-87 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMALA_RS38755 c4a8c29052c37a3881f5fb521c4cbe71 505 Pfam PF13520 Amino acid permease 41 446 7.5E-56 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMALA_RS24350 2c11ae71f896a9c0086b08683e1300d9 219 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 49 201 1.5E-65 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 SMALA_RS24350 2c11ae71f896a9c0086b08683e1300d9 219 Gene3D G3DSA:3.30.1060.10 35 216 4.9E-78 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 SMALA_RS24350 2c11ae71f896a9c0086b08683e1300d9 219 Pfam PF01625 Peptide methionine sulfoxide reductase 50 201 1.2E-65 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 SMALA_RS24350 2c11ae71f896a9c0086b08683e1300d9 219 SUPERFAMILY SSF55068 25 211 4.97E-78 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 SMALA_RS24350 2c11ae71f896a9c0086b08683e1300d9 219 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 46 207 37.11 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 SMALA_RS35320 7d8d0cc5f878297fc26584b3e525d261 66 Pfam PF00741 Gas vesicle protein 11 49 4.0E-16 T 29-03-2018 IPR000638 Gas vesicle protein GvpA GO:0005198|GO:0012506 SMALA_RS13170 152602434856a6072554eaf62b824297 314 Pfam PF04085 rod shape-determining protein MreC 131 270 1.9E-34 T 29-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 SMALA_RS13170 152602434856a6072554eaf62b824297 314 PIRSF PIRSF038471 2 285 1.8E-41 T 29-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 SMALA_RS11875 77f1d4934e6c83d765b065944e6c5027 80 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 1 48 4.4E-16 T 29-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain SMALA_RS11875 77f1d4934e6c83d765b065944e6c5027 80 SMART SM00834 1 42 4.8E-14 T 29-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain SMALA_RS11875 77f1d4934e6c83d765b065944e6c5027 80 Pfam PF09723 Zinc ribbon domain 1 40 1.1E-12 T 29-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain SMALA_RS40500 941e24794aee23254870917a9e3c7841 234 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS40500 941e24794aee23254870917a9e3c7841 234 Gene3D G3DSA:3.40.50.300 14 234 4.2E-58 T 29-03-2018 SMALA_RS40500 941e24794aee23254870917a9e3c7841 234 SMART SM00382 45 231 9.2E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS40500 941e24794aee23254870917a9e3c7841 234 Pfam PF00005 ABC transporter 36 183 4.2E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS40500 941e24794aee23254870917a9e3c7841 234 SUPERFAMILY SSF52540 18 233 1.13E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS38475 82cca76ab8507f4cfaed1921804ba08b 390 SUPERFAMILY SSF51735 6 282 1.01E-45 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS38475 82cca76ab8507f4cfaed1921804ba08b 390 Pfam PF07993 Male sterility protein 9 232 7.1E-43 T 29-03-2018 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 SMALA_RS38475 82cca76ab8507f4cfaed1921804ba08b 390 Gene3D G3DSA:3.40.50.720 1 342 3.7E-44 T 29-03-2018 SMALA_RS22905 6b34bad7ed8290050d07869a99f4ede0 393 Gene3D G3DSA:3.40.50.150 84 252 2.9E-26 T 29-03-2018 SMALA_RS22905 6b34bad7ed8290050d07869a99f4ede0 393 SUPERFAMILY SSF53335 71 231 3.61E-26 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS22905 6b34bad7ed8290050d07869a99f4ede0 393 Pfam PF13649 Methyltransferase domain 106 171 4.6E-7 T 29-03-2018 SMALA_RS19355 e510124a3d489085184f5eccbd9dce54 430 Gene3D G3DSA:1.20.1250.20 30 229 1.3E-17 T 29-03-2018 SMALA_RS19355 e510124a3d489085184f5eccbd9dce54 430 Pfam PF07690 Major Facilitator Superfamily 44 388 4.3E-21 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS19355 e510124a3d489085184f5eccbd9dce54 430 SUPERFAMILY SSF103473 31 427 4.58E-41 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS19355 e510124a3d489085184f5eccbd9dce54 430 Gene3D G3DSA:1.20.1250.20 241 429 1.9E-18 T 29-03-2018 SMALA_RS40940 f8cf44f2a6ea45356e3c9b24916b86f3 334 TIGRFAM TIGR03945 PLP_SbnA_fam: 2,3-diaminopropionate biosynthesis protein SbnA 7 306 1.5E-119 T 29-03-2018 IPR023927 2,3-diaminopropionate biosynthesis protein SbnA SMALA_RS40940 f8cf44f2a6ea45356e3c9b24916b86f3 334 SUPERFAMILY SSF53686 23 310 9.3E-75 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMALA_RS40940 f8cf44f2a6ea45356e3c9b24916b86f3 334 Gene3D G3DSA:3.40.50.1100 139 312 1.3E-39 T 29-03-2018 SMALA_RS40940 f8cf44f2a6ea45356e3c9b24916b86f3 334 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 23 290 1.5E-52 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMALA_RS40940 f8cf44f2a6ea45356e3c9b24916b86f3 334 Gene3D G3DSA:3.40.50.1100 37 138 3.8E-28 T 29-03-2018 SMALA_RS41925 d1c41347059041c49fe66d5ea8ae18fa 417 SUPERFAMILY SSF55920 189 413 2.49E-32 T 29-03-2018 IPR000994 Peptidase M24 SMALA_RS41925 d1c41347059041c49fe66d5ea8ae18fa 417 Gene3D G3DSA:3.90.230.10 181 400 6.3E-27 T 29-03-2018 SMALA_RS41925 d1c41347059041c49fe66d5ea8ae18fa 417 Gene3D G3DSA:3.40.350.10 15 180 7.2E-20 T 29-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal SMALA_RS41925 d1c41347059041c49fe66d5ea8ae18fa 417 SUPERFAMILY SSF53092 23 187 5.75E-17 T 29-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal SMALA_RS41925 d1c41347059041c49fe66d5ea8ae18fa 417 Pfam PF01321 Creatinase/Prolidase N-terminal domain 36 187 1.1E-10 T 29-03-2018 IPR000587 Creatinase, N-terminal GO:0016787 SMALA_RS41925 d1c41347059041c49fe66d5ea8ae18fa 417 Pfam PF00557 Metallopeptidase family M24 199 397 3.7E-19 T 29-03-2018 IPR000994 Peptidase M24 SMALA_RS08940 2f1132ce75cf39baa68d43b3e49e17cd 356 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 5 332 1.1E-70 T 29-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 SMALA_RS08940 2f1132ce75cf39baa68d43b3e49e17cd 356 SUPERFAMILY SSF51395 4 356 2.49E-109 T 29-03-2018 SMALA_RS08940 2f1132ce75cf39baa68d43b3e49e17cd 356 Gene3D G3DSA:3.20.20.70 1 356 4.4E-114 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS30235 ba11b705ef72bafbb499b4048a88a786 250 Gene3D G3DSA:3.40.50.1400 121 246 2.2E-22 T 29-03-2018 SMALA_RS30235 ba11b705ef72bafbb499b4048a88a786 250 Pfam PF01903 CbiX 11 115 5.3E-26 T 29-03-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 SMALA_RS30235 ba11b705ef72bafbb499b4048a88a786 250 Pfam PF01903 CbiX 139 233 2.9E-11 T 29-03-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 SMALA_RS30235 ba11b705ef72bafbb499b4048a88a786 250 Gene3D G3DSA:3.40.50.1400 1 120 2.2E-29 T 29-03-2018 SMALA_RS30235 ba11b705ef72bafbb499b4048a88a786 250 SUPERFAMILY SSF53800 5 240 5.45E-45 T 29-03-2018 SMALA_RS14725 317b27a5a373941ec6d9e7cf742fdd97 430 SMART SM00825 Beta-ketoacyl synthase 4 430 3.2E-10 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS14725 317b27a5a373941ec6d9e7cf742fdd97 430 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2 249 1.2E-28 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS14725 317b27a5a373941ec6d9e7cf742fdd97 430 SUPERFAMILY SSF53901 1 254 1.25E-41 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS14725 317b27a5a373941ec6d9e7cf742fdd97 430 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 321 384 3.8E-14 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS14725 317b27a5a373941ec6d9e7cf742fdd97 430 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 258 310 8.7E-5 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS14725 317b27a5a373941ec6d9e7cf742fdd97 430 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 164 180 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SMALA_RS14725 317b27a5a373941ec6d9e7cf742fdd97 430 SUPERFAMILY SSF53901 220 428 4.53E-42 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS14725 317b27a5a373941ec6d9e7cf742fdd97 430 Gene3D G3DSA:3.40.47.10 1 262 1.7E-54 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS14725 317b27a5a373941ec6d9e7cf742fdd97 430 Gene3D G3DSA:3.40.47.10 266 430 2.9E-32 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS27560 24d685bf36f9f7305b71272e4595bf01 369 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 258 319 2.9E-19 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMALA_RS27560 24d685bf36f9f7305b71272e4595bf01 369 SUPERFAMILY SSF52540 24 277 1.54E-68 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS27560 24d685bf36f9f7305b71272e4595bf01 369 SMART SM00382 52 256 3.5E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS27560 24d685bf36f9f7305b71272e4595bf01 369 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 257 351 9.4E-22 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMALA_RS27560 24d685bf36f9f7305b71272e4595bf01 369 Pfam PF00005 ABC transporter 44 206 3.2E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS27560 24d685bf36f9f7305b71272e4595bf01 369 Gene3D G3DSA:3.40.50.300 21 366 1.6E-78 T 29-03-2018 SMALA_RS27560 24d685bf36f9f7305b71272e4595bf01 369 ProSitePatterns PS00211 ABC transporters family signature. 179 193 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS06865 74037caf5ecbc0f3bda15680cb12a8e2 298 Gene3D G3DSA:3.30.2140.10 208 292 0.048 T 29-03-2018 SMALA_RS06865 74037caf5ecbc0f3bda15680cb12a8e2 298 Gene3D G3DSA:3.30.2140.10 46 205 3.2E-25 T 29-03-2018 SMALA_RS06865 74037caf5ecbc0f3bda15680cb12a8e2 298 SUPERFAMILY SSF54001 43 294 6.87E-60 T 29-03-2018 SMALA_RS06865 74037caf5ecbc0f3bda15680cb12a8e2 298 Pfam PF00797 N-acetyltransferase 62 287 3.0E-35 T 29-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 SMALA_RS06865 74037caf5ecbc0f3bda15680cb12a8e2 298 PRINTS PR01543 Arylamine N-acetyltransferase signature 62 85 6.2E-7 T 29-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 SMALA_RS06865 74037caf5ecbc0f3bda15680cb12a8e2 298 PRINTS PR01543 Arylamine N-acetyltransferase signature 108 130 6.2E-7 T 29-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 SMALA_RS06865 74037caf5ecbc0f3bda15680cb12a8e2 298 PRINTS PR01543 Arylamine N-acetyltransferase signature 140 165 6.2E-7 T 29-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 SMALA_RS08855 1b59282a15688af8087f04a4b9e65824 157 SUPERFAMILY SSF141322 94 156 8.24E-6 T 29-03-2018 SMALA_RS08855 1b59282a15688af8087f04a4b9e65824 157 Gene3D G3DSA:2.40.50.140 82 157 1.5E-21 T 29-03-2018 SMALA_RS08855 1b59282a15688af8087f04a4b9e65824 157 Pfam PF01957 NfeD-like C-terminal, partner-binding 23 156 2.0E-17 T 29-03-2018 IPR002810 NfeD-like, C-terminal domain SMALA_RS41325 449460f6bd27f88a8266a4b1ed120b35 339 Pfam PF02653 Branched-chain amino acid transport system / permease component 60 324 4.2E-47 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 SMALA_RS41325 449460f6bd27f88a8266a4b1ed120b35 339 Gene3D G3DSA:1.10.3470.10 23 331 1.2E-32 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SMALA_RS35820 bc132825690feafd070f3245758174de 175 Pfam PF01381 Helix-turn-helix 54 89 2.9E-6 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS35820 bc132825690feafd070f3245758174de 175 Gene3D G3DSA:1.10.260.40 9 96 7.0E-11 T 29-03-2018 SMALA_RS35820 bc132825690feafd070f3245758174de 175 SUPERFAMILY SSF47413 54 94 3.26E-6 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS01050 4dd5f5c455db9e6ce2cdee657d3241a4 646 SUPERFAMILY SSF54211 245 498 7.59E-94 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SMALA_RS01050 4dd5f5c455db9e6ce2cdee657d3241a4 646 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 47 156 9.0E-12 T 29-03-2018 SMALA_RS01050 4dd5f5c455db9e6ce2cdee657d3241a4 646 Gene3D G3DSA:3.30.565.10 2 234 3.9E-51 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS01050 4dd5f5c455db9e6ce2cdee657d3241a4 646 SUPERFAMILY SSF55874 5 216 6.16E-60 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS01050 4dd5f5c455db9e6ce2cdee657d3241a4 646 PIRSF PIRSF002583 2 646 5.4E-218 T 29-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 SMALA_RS01050 4dd5f5c455db9e6ce2cdee657d3241a4 646 Hamap MF_00505 Chaperone protein HtpG [htpG]. 3 643 30.115 T 29-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 SMALA_RS01050 4dd5f5c455db9e6ce2cdee657d3241a4 646 ProSitePatterns PS00298 Heat shock hsp90 proteins family signature. 26 35 - T 29-03-2018 IPR019805 Heat shock protein Hsp90, conserved site GO:0005524|GO:0006457|GO:0006950|GO:0051082 SMALA_RS01050 4dd5f5c455db9e6ce2cdee657d3241a4 646 SMART SM00387 28 185 1.5E-4 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS01050 4dd5f5c455db9e6ce2cdee657d3241a4 646 PRINTS PR00775 90kDa heat shock protein signature 76 93 8.8E-55 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal SMALA_RS01050 4dd5f5c455db9e6ce2cdee657d3241a4 646 PRINTS PR00775 90kDa heat shock protein signature 196 214 8.8E-55 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal SMALA_RS01050 4dd5f5c455db9e6ce2cdee657d3241a4 646 PRINTS PR00775 90kDa heat shock protein signature 123 145 8.8E-55 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal SMALA_RS01050 4dd5f5c455db9e6ce2cdee657d3241a4 646 PRINTS PR00775 90kDa heat shock protein signature 173 190 8.8E-55 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal SMALA_RS01050 4dd5f5c455db9e6ce2cdee657d3241a4 646 PRINTS PR00775 90kDa heat shock protein signature 27 49 8.8E-55 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal SMALA_RS01050 4dd5f5c455db9e6ce2cdee657d3241a4 646 PRINTS PR00775 90kDa heat shock protein signature 94 111 8.8E-55 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal SMALA_RS01050 4dd5f5c455db9e6ce2cdee657d3241a4 646 PRINTS PR00775 90kDa heat shock protein signature 6 26 8.8E-55 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal SMALA_RS01050 4dd5f5c455db9e6ce2cdee657d3241a4 646 Pfam PF00183 Hsp90 protein 226 646 1.5E-136 T 29-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 SMALA_RS01050 4dd5f5c455db9e6ce2cdee657d3241a4 646 SUPERFAMILY SSF110942 526 641 7.98E-31 T 29-03-2018 SMALA_RS40110 6e49ed3e50480cb3d6972c5aa257b761 720 Pfam PF14742 N-terminal domain of (some) glycogen debranching enzymes 45 227 1.6E-22 T 29-03-2018 IPR032856 Putative glycogen debranching enzyme, N-terminal SMALA_RS40110 6e49ed3e50480cb3d6972c5aa257b761 720 Pfam PF06202 Amylo-alpha-1,6-glucosidase 292 651 6.2E-6 T 29-03-2018 IPR032790 Glycogen debranching enzyme, C-terminal KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-6798695|Reactome: R-HSA-70221 SMALA_RS40110 6e49ed3e50480cb3d6972c5aa257b761 720 SUPERFAMILY SSF48208 254 708 5.44E-62 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 SMALA_RS40110 6e49ed3e50480cb3d6972c5aa257b761 720 Gene3D G3DSA:1.50.10.10 266 449 2.6E-22 T 29-03-2018 SMALA_RS40110 6e49ed3e50480cb3d6972c5aa257b761 720 Gene3D G3DSA:1.50.10.10 450 658 2.5E-32 T 29-03-2018 SMALA_RS18150 d7841ea38835b07b12a16cf73a65b016 235 Pfam PF09335 SNARE associated Golgi protein 41 168 1.8E-26 T 29-03-2018 IPR032816 SNARE associated Golgi protein SMALA_RS16165 2d6d07611c32d038172144ee85c142ac 298 Pfam PF12811 Bax inhibitor 1 like 43 297 4.4E-82 T 29-03-2018 IPR010539 Protein of unknown function UCP009160 SMALA_RS16165 2d6d07611c32d038172144ee85c142ac 298 PIRSF PIRSF009160 1 298 1.2E-90 T 29-03-2018 IPR010539 Protein of unknown function UCP009160 SMALA_RS25675 9ee579de5a034331ed983ec40c48b2a3 598 Gene3D G3DSA:3.90.76.10 105 227 7.8E-21 T 29-03-2018 SMALA_RS25675 9ee579de5a034331ed983ec40c48b2a3 598 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 119 513 4.7E-59 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain SMALA_RS25675 9ee579de5a034331ed983ec40c48b2a3 598 PIRSF PIRSF002741 47 590 7.4E-42 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 SMALA_RS25675 9ee579de5a034331ed983ec40c48b2a3 598 Gene3D G3DSA:3.10.105.10 364 569 9.0E-35 T 29-03-2018 SMALA_RS25675 9ee579de5a034331ed983ec40c48b2a3 598 Gene3D G3DSA:3.40.190.10 228 363 1.6E-18 T 29-03-2018 SMALA_RS25675 9ee579de5a034331ed983ec40c48b2a3 598 SUPERFAMILY SSF53850 70 587 2.31E-74 T 29-03-2018 SMALA_RS16230 31d1bb42879c612ba5420d14427f3ae1 381 SUPERFAMILY SSF55874 155 284 2.36E-14 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS16230 31d1bb42879c612ba5420d14427f3ae1 381 Gene3D G3DSA:3.30.565.10 22 281 2.6E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS40735 454860b4bc92595591233cc78ff2cb3f 440 ProSitePatterns PS00862 Oxygen oxidoreductases covalent FAD-binding site. 30 63 - T 29-03-2018 IPR006093 Oxygen oxidoreductase covalent FAD-binding site GO:0016491|GO:0055114 SMALA_RS40735 454860b4bc92595591233cc78ff2cb3f 440 SUPERFAMILY SSF56176 19 196 1.68E-50 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SMALA_RS40735 454860b4bc92595591233cc78ff2cb3f 440 Pfam PF01565 FAD binding domain 30 164 1.1E-33 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 SMALA_RS40735 454860b4bc92595591233cc78ff2cb3f 440 Gene3D G3DSA:3.30.43.10 2 80 1.5E-14 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 SMALA_RS40735 454860b4bc92595591233cc78ff2cb3f 440 Gene3D G3DSA:3.30.465.10 81 218 2.9E-39 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SMALA_RS41095 77ceeef06b49ec241aadeeb70afee268 111 Pfam PF00171 Aldehyde dehydrogenase family 1 83 2.8E-31 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS41095 77ceeef06b49ec241aadeeb70afee268 111 Gene3D G3DSA:3.40.605.10 1 98 2.0E-30 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS41095 77ceeef06b49ec241aadeeb70afee268 111 SUPERFAMILY SSF53720 1 83 1.96E-30 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMALA_RS08660 e51b6a9442e30f4ae6d0b5c1bf8cf900 224 Gene3D G3DSA:3.40.1130.10 30 221 9.1E-34 T 29-03-2018 SMALA_RS08660 e51b6a9442e30f4ae6d0b5c1bf8cf900 224 SUPERFAMILY SSF69593 22 211 3.14E-34 T 29-03-2018 SMALA_RS08660 e51b6a9442e30f4ae6d0b5c1bf8cf900 224 Pfam PF01553 Acyltransferase 33 152 3.9E-17 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SMALA_RS08660 e51b6a9442e30f4ae6d0b5c1bf8cf900 224 SMART SM00563 45 155 1.0E-21 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SMALA_RS11740 64eff2e688c6f432f656ddba12be6caa 207 Pfam PF04471 Restriction endonuclease 70 180 7.9E-23 T 29-03-2018 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 SMALA_RS11740 64eff2e688c6f432f656ddba12be6caa 207 Gene3D G3DSA:3.40.1350.10 60 182 4.0E-24 T 29-03-2018 SMALA_RS11740 64eff2e688c6f432f656ddba12be6caa 207 SUPERFAMILY SSF52980 74 183 5.9E-20 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 SMALA_RS14065 a4d0996952f8b4ec84039a1ed9e4e700 239 Gene3D G3DSA:1.10.1740.10 1 81 2.1E-22 T 29-03-2018 SMALA_RS14065 a4d0996952f8b4ec84039a1ed9e4e700 239 SUPERFAMILY SSF88946 4 104 2.24E-21 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS14065 a4d0996952f8b4ec84039a1ed9e4e700 239 Gene3D G3DSA:1.10.10.10 82 178 7.1E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS14065 a4d0996952f8b4ec84039a1ed9e4e700 239 SUPERFAMILY SSF88659 114 175 2.62E-13 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS14065 a4d0996952f8b4ec84039a1ed9e4e700 239 Pfam PF08281 Sigma-70, region 4 121 172 1.5E-13 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS14065 a4d0996952f8b4ec84039a1ed9e4e700 239 Pfam PF04542 Sigma-70 region 2 20 88 1.5E-12 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS14065 a4d0996952f8b4ec84039a1ed9e4e700 239 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 15 174 3.7E-20 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS20995 3c66a1ddbb35f7b8280d8f28645e25aa 150 Gene3D G3DSA:3.30.565.10 12 150 3.5E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS20995 3c66a1ddbb35f7b8280d8f28645e25aa 150 Pfam PF13581 Histidine kinase-like ATPase domain 21 137 9.7E-13 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS20995 3c66a1ddbb35f7b8280d8f28645e25aa 150 SUPERFAMILY SSF55874 44 139 1.35E-7 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS35580 67c68f690e00c33340cd91f332286fb6 162 Pfam PF00255 Glutathione peroxidase 3 109 1.9E-38 T 29-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 SMALA_RS35580 67c68f690e00c33340cd91f332286fb6 162 Gene3D G3DSA:3.40.30.10 1 162 5.3E-43 T 29-03-2018 SMALA_RS35580 67c68f690e00c33340cd91f332286fb6 162 PIRSF PIRSF000303 1 162 1.0E-60 T 29-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 SMALA_RS35580 67c68f690e00c33340cd91f332286fb6 162 SUPERFAMILY SSF52833 1 160 9.3E-55 T 29-03-2018 IPR012336 Thioredoxin-like fold SMALA_RS35580 67c68f690e00c33340cd91f332286fb6 162 PRINTS PR01011 Glutathione peroxidase family signature 56 72 8.3E-18 T 29-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 SMALA_RS35580 67c68f690e00c33340cd91f332286fb6 162 PRINTS PR01011 Glutathione peroxidase family signature 21 38 8.3E-18 T 29-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 SMALA_RS35580 67c68f690e00c33340cd91f332286fb6 162 PRINTS PR01011 Glutathione peroxidase family signature 122 131 8.3E-18 T 29-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 SMALA_RS29090 7ad592410e321e986ffa2d42e20f02b6 134 SUPERFAMILY SSF81901 44 127 2.09E-12 T 29-03-2018 SMALA_RS29090 7ad592410e321e986ffa2d42e20f02b6 134 Gene3D G3DSA:1.25.40.10 24 132 4.4E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS25005 11be6b47d599de995266d978884a5f60 228 Gene3D G3DSA:3.40.50.300 4 226 7.4E-59 T 29-03-2018 SMALA_RS25005 11be6b47d599de995266d978884a5f60 228 Pfam PF00005 ABC transporter 23 171 9.0E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS25005 11be6b47d599de995266d978884a5f60 228 SMART SM00382 32 220 3.0E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS25005 11be6b47d599de995266d978884a5f60 228 SUPERFAMILY SSF52540 8 224 1.45E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS11345 844364683dd70db20a06930010b6012d 391 SMART SM00855 189 346 1.2E-15 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SMALA_RS11345 844364683dd70db20a06930010b6012d 391 PIRSF PIRSF036922 1 391 3.7E-176 T 29-03-2018 IPR014636 RNase H, phosphoglycerate mutase domain-containing SMALA_RS11345 844364683dd70db20a06930010b6012d 391 Pfam PF13456 Reverse transcriptase-like 9 131 7.0E-20 T 29-03-2018 SMALA_RS11345 844364683dd70db20a06930010b6012d 391 Gene3D G3DSA:3.40.50.1240 187 391 8.7E-51 T 29-03-2018 IPR029033 Histidine phosphatase superfamily SMALA_RS11345 844364683dd70db20a06930010b6012d 391 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 190 383 2.2E-56 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SMALA_RS11345 844364683dd70db20a06930010b6012d 391 SUPERFAMILY SSF53254 188 390 7.07E-52 T 29-03-2018 IPR029033 Histidine phosphatase superfamily SMALA_RS11345 844364683dd70db20a06930010b6012d 391 SUPERFAMILY SSF53098 4 130 7.08E-30 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SMALA_RS11345 844364683dd70db20a06930010b6012d 391 Gene3D G3DSA:3.30.420.10 2 147 8.4E-29 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SMALA_RS03525 b4dff097430859b62afc3291e1f1e57d 385 SUPERFAMILY SSF50022 17 155 1.96E-43 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMALA_RS03525 b4dff097430859b62afc3291e1f1e57d 385 Gene3D G3DSA:3.90.380.10 144 384 6.1E-60 T 29-03-2018 SMALA_RS03525 b4dff097430859b62afc3291e1f1e57d 385 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 188 376 3.0E-45 T 29-03-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 SMALA_RS03525 b4dff097430859b62afc3291e1f1e57d 385 Pfam PF00355 Rieske [2Fe-2S] domain 42 127 1.1E-17 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMALA_RS03525 b4dff097430859b62afc3291e1f1e57d 385 SUPERFAMILY SSF55961 170 374 6.59E-42 T 29-03-2018 SMALA_RS03525 b4dff097430859b62afc3291e1f1e57d 385 Gene3D G3DSA:2.102.10.10 33 143 4.4E-22 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMALA_RS03525 b4dff097430859b62afc3291e1f1e57d 385 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 56 71 5.0E-21 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 SMALA_RS03525 b4dff097430859b62afc3291e1f1e57d 385 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 140 166 5.0E-21 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 SMALA_RS03525 b4dff097430859b62afc3291e1f1e57d 385 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 184 206 5.0E-21 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 SMALA_RS03525 b4dff097430859b62afc3291e1f1e57d 385 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 26 51 5.0E-21 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 SMALA_RS03525 b4dff097430859b62afc3291e1f1e57d 385 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 77 97 5.0E-21 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 SMALA_RS03525 b4dff097430859b62afc3291e1f1e57d 385 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 99 119 5.0E-21 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 SMALA_RS03625 bb1cdf84944f9fc094c1a356f39d3074 500 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 314 495 1.9E-35 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS03625 bb1cdf84944f9fc094c1a356f39d3074 500 Gene3D G3DSA:3.30.450.20 15 236 1.5E-17 T 29-03-2018 SMALA_RS03625 bb1cdf84944f9fc094c1a356f39d3074 500 SMART SM00086 183 225 0.0079 T 29-03-2018 IPR001610 PAC motif SMALA_RS03625 bb1cdf84944f9fc094c1a356f39d3074 500 Pfam PF08447 PAS fold 132 213 3.1E-9 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 SMALA_RS03625 bb1cdf84944f9fc094c1a356f39d3074 500 Gene3D G3DSA:3.60.40.10 237 498 1.4E-26 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS03625 bb1cdf84944f9fc094c1a356f39d3074 500 SMART SM00331 288 495 8.4E-12 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS03625 bb1cdf84944f9fc094c1a356f39d3074 500 SUPERFAMILY SSF55785 130 234 2.62E-12 T 29-03-2018 IPR000014 PAS domain SMALA_RS28480 d4537278211fe70b640a82d89fb73395 98 Gene3D G3DSA:3.30.70.1120 2 92 5.1E-35 T 29-03-2018 SMALA_RS28480 d4537278211fe70b640a82d89fb73395 98 SUPERFAMILY SSF103007 1 93 1.26E-30 T 29-03-2018 IPR007546 Protein of unknown function DUF503 SMALA_RS28480 d4537278211fe70b640a82d89fb73395 98 Pfam PF04456 Protein of unknown function (DUF503) 3 89 6.7E-33 T 29-03-2018 IPR007546 Protein of unknown function DUF503 SMALA_RS13625 80721247d23e148df11e719df5479baf 311 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 2.0E-23 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS13625 80721247d23e148df11e719df5479baf 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 5.1E-11 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS13625 80721247d23e148df11e719df5479baf 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 5.1E-11 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS13625 80721247d23e148df11e719df5479baf 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 5.1E-11 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS13625 80721247d23e148df11e719df5479baf 311 SUPERFAMILY SSF53850 90 295 1.17E-44 T 29-03-2018 SMALA_RS13625 80721247d23e148df11e719df5479baf 311 SUPERFAMILY SSF46785 3 111 5.36E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS13625 80721247d23e148df11e719df5479baf 311 Gene3D G3DSA:3.40.190.10 91 179 1.9E-24 T 29-03-2018 SMALA_RS13625 80721247d23e148df11e719df5479baf 311 Pfam PF03466 LysR substrate binding domain 87 292 1.2E-48 T 29-03-2018 IPR005119 LysR, substrate-binding SMALA_RS13625 80721247d23e148df11e719df5479baf 311 Gene3D G3DSA:1.10.10.10 1 83 1.6E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS13625 80721247d23e148df11e719df5479baf 311 Gene3D G3DSA:3.40.190.10 180 266 4.4E-22 T 29-03-2018 SMALA_RS18175 b7f3afd93a50cc311ee70021320c8402 261 Pfam PF01061 ABC-2 type transporter 10 217 6.9E-24 T 29-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 SMALA_RS18175 b7f3afd93a50cc311ee70021320c8402 261 PIRSF PIRSF006648 1 261 3.3E-72 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMALA_RS02965 5ea5eb698eab87ec0676ff5263da9f9f 421 Pfam PF13520 Amino acid permease 18 395 3.3E-40 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMALA_RS02965 5ea5eb698eab87ec0676ff5263da9f9f 421 PIRSF PIRSF006060 5 416 9.9E-68 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMALA_RS04510 10a90f3ae0f245ac6fde29ba6868801d 448 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 256 278 2.6E-21 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 SMALA_RS04510 10a90f3ae0f245ac6fde29ba6868801d 448 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 329 343 2.6E-21 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 SMALA_RS04510 10a90f3ae0f245ac6fde29ba6868801d 448 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 314 328 2.6E-21 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 SMALA_RS04510 10a90f3ae0f245ac6fde29ba6868801d 448 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 110 129 2.6E-21 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 SMALA_RS04510 10a90f3ae0f245ac6fde29ba6868801d 448 SUPERFAMILY SSF56601 77 447 2.73E-59 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMALA_RS04510 10a90f3ae0f245ac6fde29ba6868801d 448 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 220 442 2.8E-63 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 SMALA_RS04510 10a90f3ae0f245ac6fde29ba6868801d 448 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 73 215 7.4E-34 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 SMALA_RS04510 10a90f3ae0f245ac6fde29ba6868801d 448 Gene3D G3DSA:3.40.710.10 72 446 3.6E-29 T 29-03-2018 SMALA_RS04510 10a90f3ae0f245ac6fde29ba6868801d 448 TIGRFAM TIGR00666 PBP4: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase 220 424 5.4E-39 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 SMALA_RS35410 06430e7967ec0594120d7c7805605b1b 332 Gene3D G3DSA:2.60.40.420 200 331 1.3E-25 T 29-03-2018 IPR008972 Cupredoxin SMALA_RS35410 06430e7967ec0594120d7c7805605b1b 332 Pfam PF07731 Multicopper oxidase 209 315 9.6E-14 T 29-03-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 SMALA_RS35410 06430e7967ec0594120d7c7805605b1b 332 SUPERFAMILY SSF49503 199 319 2.01E-22 T 29-03-2018 IPR008972 Cupredoxin SMALA_RS35410 06430e7967ec0594120d7c7805605b1b 332 Gene3D G3DSA:2.60.40.420 56 199 4.8E-26 T 29-03-2018 IPR008972 Cupredoxin SMALA_RS35410 06430e7967ec0594120d7c7805605b1b 332 ProSitePatterns PS00080 Multicopper oxidases signature 2. 296 307 - T 29-03-2018 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 SMALA_RS35410 06430e7967ec0594120d7c7805605b1b 332 SUPERFAMILY SSF49503 79 210 9.87E-18 T 29-03-2018 IPR008972 Cupredoxin SMALA_RS35410 06430e7967ec0594120d7c7805605b1b 332 Pfam PF07732 Multicopper oxidase 82 190 1.7E-11 T 29-03-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 SMALA_RS28370 c9c3e0f6bb0e988266e1f8cace1648a3 449 Gene3D G3DSA:3.40.640.10 112 327 1.1E-47 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS28370 c9c3e0f6bb0e988266e1f8cace1648a3 449 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 262 299 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMALA_RS28370 c9c3e0f6bb0e988266e1f8cace1648a3 449 PIRSF PIRSF000521 4 153 8.8E-8 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMALA_RS28370 c9c3e0f6bb0e988266e1f8cace1648a3 449 PIRSF PIRSF000521 145 449 7.9E-32 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMALA_RS28370 c9c3e0f6bb0e988266e1f8cace1648a3 449 Pfam PF00202 Aminotransferase class-III 44 445 2.7E-123 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMALA_RS28370 c9c3e0f6bb0e988266e1f8cace1648a3 449 Gene3D G3DSA:3.90.1150.10 24 111 8.2E-5 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS28370 c9c3e0f6bb0e988266e1f8cace1648a3 449 SUPERFAMILY SSF53383 42 448 1.46E-124 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS28370 c9c3e0f6bb0e988266e1f8cace1648a3 449 Gene3D G3DSA:3.90.1150.10 328 449 3.7E-38 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS28370 c9c3e0f6bb0e988266e1f8cace1648a3 449 TIGRFAM TIGR00700 GABAtrnsam: 4-aminobutyrate transaminase 31 447 9.9E-180 T 29-03-2018 IPR004632 4-aminobutyrate aminotransferase, bacterial GO:0003867|GO:0009448 SMALA_RS05020 c596b8e096ea358266444aa7115235c9 383 Gene3D G3DSA:3.20.20.30 9 370 2.4E-80 T 29-03-2018 SMALA_RS05020 c596b8e096ea358266444aa7115235c9 383 Pfam PF00296 Luciferase-like monooxygenase 25 337 2.7E-72 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS05020 c596b8e096ea358266444aa7115235c9 383 SUPERFAMILY SSF51679 20 368 8.77E-80 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS24305 6b2b0e55cce2a13f32a57f1ae417db61 352 SUPERFAMILY SSF52242 93 214 9.68E-19 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 SMALA_RS24305 6b2b0e55cce2a13f32a57f1ae417db61 352 Gene3D G3DSA:3.40.50.280 95 215 2.9E-22 T 29-03-2018 SMALA_RS24305 6b2b0e55cce2a13f32a57f1ae417db61 352 Pfam PF02607 B12 binding domain 17 82 4.0E-12 T 29-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMALA_RS24305 6b2b0e55cce2a13f32a57f1ae417db61 352 Pfam PF02310 B12 binding domain 97 211 6.6E-15 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 SMALA_RS14615 db91e2b6c53db7b8d8124d2eb61eaa92 216 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 35 214 1.8E-22 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS14615 db91e2b6c53db7b8d8124d2eb61eaa92 216 TIGRFAM TIGR03003 ectoine_ehuD: ectoine/hydroxyectoine ABC transporter, permease protein EhuD 3 214 7.3E-84 T 29-03-2018 IPR014341 Ectoine/hydroxyectoine ABC transporter, permease protein EhuD SMALA_RS14615 db91e2b6c53db7b8d8124d2eb61eaa92 216 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 109 3.2E-30 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 SMALA_RS14615 db91e2b6c53db7b8d8124d2eb61eaa92 216 Gene3D G3DSA:1.10.3720.10 1 216 2.8E-42 T 29-03-2018 SMALA_RS14615 db91e2b6c53db7b8d8124d2eb61eaa92 216 SUPERFAMILY SSF161098 14 200 6.15E-41 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS05095 bf602abe338e272a438137572458c281 306 SUPERFAMILY SSF53474 58 297 2.18E-28 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS05095 bf602abe338e272a438137572458c281 306 Pfam PF12697 Alpha/beta hydrolase family 81 271 2.1E-12 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS05095 bf602abe338e272a438137572458c281 306 Gene3D G3DSA:3.40.50.1820 4 305 3.3E-28 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS05095 bf602abe338e272a438137572458c281 306 PRINTS PR00111 Alpha/beta hydrolase fold signature 104 119 7.0E-6 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS05095 bf602abe338e272a438137572458c281 306 PRINTS PR00111 Alpha/beta hydrolase fold signature 149 162 7.0E-6 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS05095 bf602abe338e272a438137572458c281 306 PRINTS PR00111 Alpha/beta hydrolase fold signature 163 176 7.0E-6 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS12260 3e714a05a9db49c0cfca595f6920bd69 461 Gene3D G3DSA:3.40.190.10 54 220 4.3E-34 T 29-03-2018 SMALA_RS12260 3e714a05a9db49c0cfca595f6920bd69 461 SUPERFAMILY SSF53850 28 454 9.93E-66 T 29-03-2018 SMALA_RS12260 3e714a05a9db49c0cfca595f6920bd69 461 Gene3D G3DSA:3.40.190.10 221 436 1.6E-7 T 29-03-2018 SMALA_RS12260 3e714a05a9db49c0cfca595f6920bd69 461 Pfam PF13416 Bacterial extracellular solute-binding protein 81 391 5.8E-30 T 29-03-2018 SMALA_RS01545 ab0294acad7a0e39568d6b9b0c657b5c 310 Pfam PF00561 alpha/beta hydrolase fold 58 157 1.6E-23 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS01545 ab0294acad7a0e39568d6b9b0c657b5c 310 PRINTS PR00111 Alpha/beta hydrolase fold signature 83 98 2.2E-10 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS01545 ab0294acad7a0e39568d6b9b0c657b5c 310 PRINTS PR00111 Alpha/beta hydrolase fold signature 128 141 2.2E-10 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS01545 ab0294acad7a0e39568d6b9b0c657b5c 310 PRINTS PR00111 Alpha/beta hydrolase fold signature 142 155 2.2E-10 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS01545 ab0294acad7a0e39568d6b9b0c657b5c 310 PRINTS PR00111 Alpha/beta hydrolase fold signature 236 250 2.2E-10 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS01545 ab0294acad7a0e39568d6b9b0c657b5c 310 SUPERFAMILY SSF53474 36 288 6.08E-48 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS01545 ab0294acad7a0e39568d6b9b0c657b5c 310 Gene3D G3DSA:3.40.50.1820 17 298 6.5E-45 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS25320 0cfbc1e016ca2a154d11d6c3d42e3996 207 Gene3D G3DSA:1.10.357.10 56 199 2.8E-17 T 29-03-2018 SMALA_RS25320 0cfbc1e016ca2a154d11d6c3d42e3996 207 SUPERFAMILY SSF46689 4 74 4.41E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS25320 0cfbc1e016ca2a154d11d6c3d42e3996 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 57 3.8E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS25320 0cfbc1e016ca2a154d11d6c3d42e3996 207 Gene3D G3DSA:1.10.10.60 1 55 4.0E-13 T 29-03-2018 SMALA_RS40910 6932e1d337562158430b48326d6f7f1e 262 Pfam PF01061 ABC-2 type transporter 8 214 6.5E-34 T 29-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 SMALA_RS40910 6932e1d337562158430b48326d6f7f1e 262 PRINTS PR00164 ABC-2 type transport system membrane protein signature 101 126 9.3E-9 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMALA_RS40910 6932e1d337562158430b48326d6f7f1e 262 PRINTS PR00164 ABC-2 type transport system membrane protein signature 174 193 9.3E-9 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMALA_RS40910 6932e1d337562158430b48326d6f7f1e 262 PRINTS PR00164 ABC-2 type transport system membrane protein signature 54 76 9.3E-9 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMALA_RS40910 6932e1d337562158430b48326d6f7f1e 262 PIRSF PIRSF006648 1 261 6.0E-69 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMALA_RS22855 95534541f6634ccae6cdf16c97ebf059 854 Pfam PF00486 Transcriptional regulatory protein, C terminal 27 99 5.9E-8 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS22855 95534541f6634ccae6cdf16c97ebf059 854 Gene3D G3DSA:1.10.10.10 11 107 8.2E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS22855 95534541f6634ccae6cdf16c97ebf059 854 Pfam PF03704 Bacterial transcriptional activator domain 106 247 3.1E-40 T 29-03-2018 IPR005158 Bacterial transcriptional activator domain SMALA_RS22855 95534541f6634ccae6cdf16c97ebf059 854 Gene3D G3DSA:1.25.40.10 108 284 1.1E-29 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS22855 95534541f6634ccae6cdf16c97ebf059 854 SUPERFAMILY SSF48452 102 265 3.37E-31 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS22855 95534541f6634ccae6cdf16c97ebf059 854 Gene3D G3DSA:1.25.40.10 660 832 0.068 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS22855 95534541f6634ccae6cdf16c97ebf059 854 SMART SM00862 20 99 3.2E-8 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS22855 95534541f6634ccae6cdf16c97ebf059 854 SMART SM01043 106 247 4.8E-50 T 29-03-2018 IPR005158 Bacterial transcriptional activator domain SMALA_RS22855 95534541f6634ccae6cdf16c97ebf059 854 SUPERFAMILY SSF46894 14 99 4.54E-10 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS29265 d91b47362105256a3f79925b5fa2e6be 142 Gene3D G3DSA:3.30.450.30 5 133 1.0E-35 T 29-03-2018 SMALA_RS29265 d91b47362105256a3f79925b5fa2e6be 142 SUPERFAMILY SSF103196 5 130 1.15E-24 T 29-03-2018 SMALA_RS29265 d91b47362105256a3f79925b5fa2e6be 142 SMART SM00960 10 101 3.3E-16 T 29-03-2018 IPR004942 Roadblock/LAMTOR2 domain SMALA_RS29265 d91b47362105256a3f79925b5fa2e6be 142 Pfam PF03259 Roadblock/LC7 domain 13 100 1.5E-19 T 29-03-2018 IPR004942 Roadblock/LAMTOR2 domain SMALA_RS27980 530449345935578ee51abe7cb55110f2 61 SUPERFAMILY SSF143800 2 59 2.16E-24 T 29-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS27980 530449345935578ee51abe7cb55110f2 61 Pfam PF00830 Ribosomal L28 family 4 58 1.0E-24 T 29-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS27980 530449345935578ee51abe7cb55110f2 61 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 61 17.533 T 29-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS27980 530449345935578ee51abe7cb55110f2 61 Gene3D G3DSA:2.30.170.40 2 61 2.1E-24 T 29-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS27980 530449345935578ee51abe7cb55110f2 61 TIGRFAM TIGR00009 L28: ribosomal protein bL28 2 56 1.0E-24 T 29-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS31150 23e460cc3b83ef52f070ec82ea21e16b 200 Pfam PF00583 Acetyltransferase (GNAT) family 35 136 1.3E-20 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SMALA_RS31150 23e460cc3b83ef52f070ec82ea21e16b 200 Gene3D G3DSA:3.40.630.30 1 147 1.5E-28 T 29-03-2018 SMALA_RS31150 23e460cc3b83ef52f070ec82ea21e16b 200 SUPERFAMILY SSF55729 1 140 7.03E-30 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS27620 fcc6e5b6838f6140fbc29a4efff4df28 349 Pfam PF13411 MerR HTH family regulatory protein 44 110 3.3E-15 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS27620 fcc6e5b6838f6140fbc29a4efff4df28 349 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 79 99 2.0E-6 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS27620 fcc6e5b6838f6140fbc29a4efff4df28 349 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 44 55 2.0E-6 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS27620 fcc6e5b6838f6140fbc29a4efff4df28 349 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 55 68 2.0E-6 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS27620 fcc6e5b6838f6140fbc29a4efff4df28 349 SMART SM00422 43 112 1.6E-23 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS27620 fcc6e5b6838f6140fbc29a4efff4df28 349 Gene3D G3DSA:1.10.1660.10 39 98 8.7E-20 T 29-03-2018 SMALA_RS27620 fcc6e5b6838f6140fbc29a4efff4df28 349 Gene3D G3DSA:1.10.1660.10 99 164 1.5E-6 T 29-03-2018 SMALA_RS27620 fcc6e5b6838f6140fbc29a4efff4df28 349 SUPERFAMILY SSF46955 43 145 4.03E-24 T 29-03-2018 IPR009061 Putative DNA-binding domain SMALA_RS41575 ff1875ecab9b1aa12181c7fcc12c6834 389 Gene3D G3DSA:1.10.540.10 2 108 5.8E-13 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS41575 ff1875ecab9b1aa12181c7fcc12c6834 389 Gene3D G3DSA:2.40.110.10 113 194 5.3E-18 T 29-03-2018 SMALA_RS41575 ff1875ecab9b1aa12181c7fcc12c6834 389 SUPERFAMILY SSF47203 231 367 1.9E-13 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMALA_RS41575 ff1875ecab9b1aa12181c7fcc12c6834 389 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 235 367 9.2E-35 T 29-03-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain SMALA_RS41575 ff1875ecab9b1aa12181c7fcc12c6834 389 PIRSF PIRSF016578 1 389 1.7E-120 T 29-03-2018 SMALA_RS41575 ff1875ecab9b1aa12181c7fcc12c6834 389 Gene3D G3DSA:1.20.140.10 195 364 5.4E-15 T 29-03-2018 SMALA_RS41575 ff1875ecab9b1aa12181c7fcc12c6834 389 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 17 82 3.2E-7 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS41575 ff1875ecab9b1aa12181c7fcc12c6834 389 SUPERFAMILY SSF56645 13 203 5.76E-38 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMALA_RS23925 0ff24b4d681e797a35ddd4645a94cec9 547 SUPERFAMILY SSF56601 246 544 5.44E-54 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMALA_RS23925 0ff24b4d681e797a35ddd4645a94cec9 547 Pfam PF05223 NTF2-like N-terminal transpeptidase domain 62 169 3.4E-8 T 29-03-2018 IPR007887 NTF2-like N-terminal transpeptidase GO:0046677 SMALA_RS23925 0ff24b4d681e797a35ddd4645a94cec9 547 Gene3D G3DSA:3.40.710.10 245 545 2.7E-57 T 29-03-2018 SMALA_RS23925 0ff24b4d681e797a35ddd4645a94cec9 547 Pfam PF00905 Penicillin binding protein transpeptidase domain 271 543 1.3E-35 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 SMALA_RS23925 0ff24b4d681e797a35ddd4645a94cec9 547 Gene3D G3DSA:3.10.450.100 58 164 0.0022 T 29-03-2018 SMALA_RS33805 6ac7e683199e1140def7a773228f3bcc 279 SUPERFAMILY SSF100950 85 271 2.55E-35 T 29-03-2018 SMALA_RS33805 6ac7e683199e1140def7a773228f3bcc 279 Pfam PF02589 LUD domain 179 271 1.6E-17 T 29-03-2018 IPR003741 LUD domain SMALA_RS33805 6ac7e683199e1140def7a773228f3bcc 279 Gene3D G3DSA:3.40.50.10420 83 272 7.0E-47 T 29-03-2018 SMALA_RS02715 90dbe4de0bbda18aa5c370e7ccf084b9 157 Pfam PF07080 Protein of unknown function (DUF1348) 10 139 1.8E-67 T 29-03-2018 IPR009783 Protein of unknown function DUF1348 SMALA_RS02715 90dbe4de0bbda18aa5c370e7ccf084b9 157 SUPERFAMILY SSF54427 5 157 4.85E-83 T 29-03-2018 IPR032710 NTF2-like domain SMALA_RS02715 90dbe4de0bbda18aa5c370e7ccf084b9 157 Gene3D G3DSA:3.10.450.50 13 157 7.4E-74 T 29-03-2018 SMALA_RS13470 557f088ff02f5c6b6ba3a1ef1437f6f1 886 SUPERFAMILY SSF48452 657 755 1.65E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS13470 557f088ff02f5c6b6ba3a1ef1437f6f1 886 Pfam PF16918 Protein kinase G tetratricopeptide repeat 581 884 6.1E-89 T 29-03-2018 IPR031636 Protein kinase G, tetratricopeptide repeat containing domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 SMALA_RS13470 557f088ff02f5c6b6ba3a1ef1437f6f1 886 Gene3D G3DSA:3.30.200.20 240 339 7.1E-15 T 29-03-2018 SMALA_RS13470 557f088ff02f5c6b6ba3a1ef1437f6f1 886 Pfam PF16919 Protein kinase G rubredoxin domain 117 249 2.9E-42 T 29-03-2018 IPR031634 Protein kinase G, rubredoxin domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 SMALA_RS13470 557f088ff02f5c6b6ba3a1ef1437f6f1 886 Gene3D G3DSA:1.10.510.10 340 521 5.0E-21 T 29-03-2018 SMALA_RS13470 557f088ff02f5c6b6ba3a1ef1437f6f1 886 SUPERFAMILY SSF56112 241 520 3.65E-40 T 29-03-2018 IPR011009 Protein kinase-like domain SMALA_RS13470 557f088ff02f5c6b6ba3a1ef1437f6f1 886 Pfam PF00069 Protein kinase domain 255 450 3.2E-24 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMALA_RS13470 557f088ff02f5c6b6ba3a1ef1437f6f1 886 Gene3D G3DSA:1.25.40.10 705 777 9.9E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS13470 557f088ff02f5c6b6ba3a1ef1437f6f1 886 Gene3D G3DSA:1.25.40.10 522 704 6.8E-35 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS13470 557f088ff02f5c6b6ba3a1ef1437f6f1 886 SMART SM00220 250 505 5.3E-13 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMALA_RS20615 68fec294f9c0f477425763d2fd343431 191 Pfam PF00692 dUTPase 70 176 1.9E-9 T 29-03-2018 IPR029054 dUTPase-like SMALA_RS20615 68fec294f9c0f477425763d2fd343431 191 Gene3D G3DSA:2.70.40.10 1 159 6.9E-46 T 29-03-2018 SMALA_RS20615 68fec294f9c0f477425763d2fd343431 191 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 3 181 7.9E-64 T 29-03-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 KEGG: 00240+3.5.4.13|MetaCyc: PWY-7187 SMALA_RS20615 68fec294f9c0f477425763d2fd343431 191 SUPERFAMILY SSF51283 2 184 2.09E-56 T 29-03-2018 IPR029054 dUTPase-like SMALA_RS20615 68fec294f9c0f477425763d2fd343431 191 Hamap MF_00146 dCTP deaminase [dcd]. 1 182 34.406 T 29-03-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 KEGG: 00240+3.5.4.13|MetaCyc: PWY-7187 SMALA_RS03515 c10a7385b317bec5af68514ca0c484de 829 Gene3D G3DSA:2.40.30.110 738 816 5.2E-24 T 29-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 SMALA_RS03515 c10a7385b317bec5af68514ca0c484de 829 Gene3D G3DSA:3.30.1360.120 432 585 1.9E-25 T 29-03-2018 SMALA_RS03515 c10a7385b317bec5af68514ca0c484de 829 Gene3D G3DSA:3.30.1360.120 586 694 2.4E-20 T 29-03-2018 SMALA_RS03515 c10a7385b317bec5af68514ca0c484de 829 SUPERFAMILY SSF51905 11 226 3.56E-65 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS03515 c10a7385b317bec5af68514ca0c484de 829 SUPERFAMILY SSF51905 341 424 3.56E-65 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS03515 c10a7385b317bec5af68514ca0c484de 829 Gene3D G3DSA:3.30.9.10 93 164 9.3E-10 T 29-03-2018 SMALA_RS03515 c10a7385b317bec5af68514ca0c484de 829 Gene3D G3DSA:3.50.50.60 6 86 1.6E-7 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS03515 c10a7385b317bec5af68514ca0c484de 829 Pfam PF01571 Aminomethyltransferase folate-binding domain 438 718 1.7E-75 T 29-03-2018 IPR006222 Glycine cleavage T-protein-like, N-terminal SMALA_RS03515 c10a7385b317bec5af68514ca0c484de 829 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 724 816 7.4E-19 T 29-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 SMALA_RS03515 c10a7385b317bec5af68514ca0c484de 829 SUPERFAMILY SSF54373 226 340 1.18E-29 T 29-03-2018 SMALA_RS03515 c10a7385b317bec5af68514ca0c484de 829 Gene3D G3DSA:3.30.9.10 165 340 2.5E-37 T 29-03-2018 SMALA_RS03515 c10a7385b317bec5af68514ca0c484de 829 Pfam PF01266 FAD dependent oxidoreductase 12 377 2.2E-51 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 SMALA_RS03515 c10a7385b317bec5af68514ca0c484de 829 SUPERFAMILY SSF101790 742 828 1.8E-23 T 29-03-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain SMALA_RS03515 c10a7385b317bec5af68514ca0c484de 829 Pfam PF16350 FAD dependent oxidoreductase central domain 380 435 9.2E-20 T 29-03-2018 IPR032503 FAD dependent oxidoreductase, central domain SMALA_RS03515 c10a7385b317bec5af68514ca0c484de 829 Gene3D G3DSA:4.10.1250.10 696 737 3.5E-16 T 29-03-2018 SMALA_RS03515 c10a7385b317bec5af68514ca0c484de 829 SUPERFAMILY SSF103025 430 733 1.04E-92 T 29-03-2018 SMALA_RS26270 0b854da430540756bdc447fcbd1bcb00 170 Pfam PF13581 Histidine kinase-like ATPase domain 23 135 1.3E-10 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS26270 0b854da430540756bdc447fcbd1bcb00 170 SUPERFAMILY SSF55874 49 141 3.37E-9 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS26270 0b854da430540756bdc447fcbd1bcb00 170 Gene3D G3DSA:3.30.565.10 14 157 3.7E-14 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS21475 1039b63725a5b9993a7e0fe33e8be4e7 121 Gene3D G3DSA:3.40.1260.10 1 115 1.8E-26 T 29-03-2018 SMALA_RS21475 1039b63725a5b9993a7e0fe33e8be4e7 121 SUPERFAMILY SSF75169 3 112 1.85E-19 T 29-03-2018 IPR027396 DsrEFH-like SMALA_RS21475 1039b63725a5b9993a7e0fe33e8be4e7 121 Pfam PF02635 DsrE/DsrF-like family 3 107 7.5E-11 T 29-03-2018 IPR003787 Sulphur relay, DsrE/F-like protein SMALA_RS12215 8b81a153f7b2304d765461a3cb45d15e 148 Gene3D G3DSA:3.90.190.10 25 147 2.5E-15 T 29-03-2018 IPR029021 Protein-tyrosine phosphatase-like SMALA_RS12215 8b81a153f7b2304d765461a3cb45d15e 148 Pfam PF00102 Protein-tyrosine phosphatase 56 119 2.6E-6 T 29-03-2018 IPR000242 PTP type protein phosphatase GO:0004725|GO:0006470 SMALA_RS12215 8b81a153f7b2304d765461a3cb45d15e 148 SUPERFAMILY SSF52799 54 145 1.17E-20 T 29-03-2018 IPR029021 Protein-tyrosine phosphatase-like SMALA_RS34840 49e04ef856c593ae59e608f0a58c45a5 139 Gene3D G3DSA:3.30.450.30 9 136 2.0E-35 T 29-03-2018 SMALA_RS34840 49e04ef856c593ae59e608f0a58c45a5 139 Pfam PF03259 Roadblock/LC7 domain 12 104 1.1E-21 T 29-03-2018 IPR004942 Roadblock/LAMTOR2 domain SMALA_RS34840 49e04ef856c593ae59e608f0a58c45a5 139 SUPERFAMILY SSF103196 11 133 3.49E-27 T 29-03-2018 SMALA_RS34840 49e04ef856c593ae59e608f0a58c45a5 139 SMART SM00960 13 104 1.2E-21 T 29-03-2018 IPR004942 Roadblock/LAMTOR2 domain SMALA_RS33050 c8b69f62c173959f99cb7aa11d9d6d61 367 SUPERFAMILY SSF56796 19 362 1.83E-98 T 29-03-2018 SMALA_RS33050 c8b69f62c173959f99cb7aa11d9d6d61 367 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 23 350 2.2E-105 T 29-03-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 SMALA_RS33050 c8b69f62c173959f99cb7aa11d9d6d61 367 PIRSF PIRSF001455 21 365 2.0E-98 T 29-03-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 SMALA_RS33050 c8b69f62c173959f99cb7aa11d9d6d61 367 Gene3D G3DSA:1.20.1090.10 181 367 1.0E-58 T 29-03-2018 SMALA_RS33050 c8b69f62c173959f99cb7aa11d9d6d61 367 Gene3D G3DSA:3.40.50.1970 14 180 2.0E-40 T 29-03-2018 SMALA_RS33050 c8b69f62c173959f99cb7aa11d9d6d61 367 Pfam PF01761 3-dehydroquinate synthase 75 331 2.0E-92 T 29-03-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 SMALA_RS33050 c8b69f62c173959f99cb7aa11d9d6d61 367 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 12 364 36.293 T 29-03-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 SMALA_RS40280 cdbf9e365007562f6cc5ea7b8a2e8758 87 SMART SM00342 1 58 4.4E-4 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS40280 cdbf9e365007562f6cc5ea7b8a2e8758 87 SUPERFAMILY SSF46689 8 62 8.06E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS40280 cdbf9e365007562f6cc5ea7b8a2e8758 87 Pfam PF12833 Helix-turn-helix domain 2 60 5.8E-17 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS40280 cdbf9e365007562f6cc5ea7b8a2e8758 87 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 27 42 2.5E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SMALA_RS40280 cdbf9e365007562f6cc5ea7b8a2e8758 87 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 42 58 2.5E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SMALA_RS40280 cdbf9e365007562f6cc5ea7b8a2e8758 87 Gene3D G3DSA:1.10.10.60 2 67 2.7E-15 T 29-03-2018 SMALA_RS29525 6a3b2063f431cadc2f10fdff97d9de0c 325 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 12 309 7.7E-108 T 29-03-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 SMALA_RS29525 6a3b2063f431cadc2f10fdff97d9de0c 325 SUPERFAMILY SSF52540 3 225 7.48E-64 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS29525 6a3b2063f431cadc2f10fdff97d9de0c 325 SMART SM00382 29 213 2.7E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS29525 6a3b2063f431cadc2f10fdff97d9de0c 325 Pfam PF13732 Domain of unknown function (DUF4162) 217 307 2.9E-8 T 29-03-2018 IPR025302 Domain of unknown function DUF4162 SMALA_RS29525 6a3b2063f431cadc2f10fdff97d9de0c 325 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS29525 6a3b2063f431cadc2f10fdff97d9de0c 325 Pfam PF00005 ABC transporter 20 163 4.6E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS29525 6a3b2063f431cadc2f10fdff97d9de0c 325 Gene3D G3DSA:3.40.50.300 1 246 9.3E-68 T 29-03-2018 SMALA_RS05875 7833f7b55f31c59e756aaeb55d5dd7f0 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 1.9E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS05875 7833f7b55f31c59e756aaeb55d5dd7f0 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 1.9E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS05875 7833f7b55f31c59e756aaeb55d5dd7f0 192 SUPERFAMILY SSF46689 8 75 4.25E-19 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS05875 7833f7b55f31c59e756aaeb55d5dd7f0 192 Gene3D G3DSA:1.10.10.60 8 41 8.3E-21 T 29-03-2018 SMALA_RS05875 7833f7b55f31c59e756aaeb55d5dd7f0 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 57 5.5E-19 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS05875 7833f7b55f31c59e756aaeb55d5dd7f0 192 Gene3D G3DSA:1.10.260.40 42 131 1.2E-12 T 29-03-2018 SMALA_RS29295 b30e73ad88999ab272f4854b082a12fd 447 Pfam PF01938 TRAM domain 8 67 9.3E-14 T 29-03-2018 IPR002792 TRAM domain SMALA_RS29295 b30e73ad88999ab272f4854b082a12fd 447 Gene3D G3DSA:3.40.50.150 84 441 4.3E-43 T 29-03-2018 SMALA_RS29295 b30e73ad88999ab272f4854b082a12fd 447 Gene3D G3DSA:2.40.50.140 1 83 2.6E-20 T 29-03-2018 SMALA_RS29295 b30e73ad88999ab272f4854b082a12fd 447 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 368 441 1.1E-9 T 29-03-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 SMALA_RS29295 b30e73ad88999ab272f4854b082a12fd 447 SUPERFAMILY SSF50249 10 56 8.0E-10 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMALA_RS29295 b30e73ad88999ab272f4854b082a12fd 447 SUPERFAMILY SSF53335 75 442 1.1E-54 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS29295 b30e73ad88999ab272f4854b082a12fd 447 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 286 349 2.4E-4 T 29-03-2018 SMALA_RS22540 796e21158f845bab7f9a7c9d5817a764 219 Gene3D G3DSA:3.40.1370.10 4 142 1.6E-50 T 29-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 SMALA_RS22540 796e21158f845bab7f9a7c9d5817a764 219 Gene3D G3DSA:3.40.1370.10 143 206 6.0E-12 T 29-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 SMALA_RS22540 796e21158f845bab7f9a7c9d5817a764 219 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 19 204 6.7E-70 T 29-03-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS22540 796e21158f845bab7f9a7c9d5817a764 219 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 11 209 32.694 T 29-03-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS22540 796e21158f845bab7f9a7c9d5817a764 219 SUPERFAMILY SSF52166 5 205 1.06E-73 T 29-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 SMALA_RS22540 796e21158f845bab7f9a7c9d5817a764 219 Pfam PF00573 Ribosomal protein L4/L1 family 19 204 1.2E-63 T 29-03-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 SMALA_RS35415 2faa65bc78b0d54a50a479af73dc560f 829 Gene3D G3DSA:3.40.50.880 59 297 1.0E-50 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS35415 2faa65bc78b0d54a50a479af73dc560f 829 Gene3D G3DSA:2.120.10.30 298 815 3.6E-67 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like SMALA_RS35415 2faa65bc78b0d54a50a479af73dc560f 829 Pfam PF07995 Glucose / Sorbosone dehydrogenase 378 617 4.8E-25 T 29-03-2018 IPR012938 Glucose/Sorbosone dehydrogenase SMALA_RS35415 2faa65bc78b0d54a50a479af73dc560f 829 SUPERFAMILY SSF52317 63 287 2.98E-35 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS35415 2faa65bc78b0d54a50a479af73dc560f 829 SUPERFAMILY SSF50952 315 639 3.92E-17 T 29-03-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 SMALA_RS35415 2faa65bc78b0d54a50a479af73dc560f 829 SUPERFAMILY SSF50952 704 798 3.92E-17 T 29-03-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 SMALA_RS35415 2faa65bc78b0d54a50a479af73dc560f 829 Pfam PF06283 Trehalose utilisation 64 283 1.6E-73 T 29-03-2018 IPR029010 ThuA-like domain SMALA_RS25255 b7b96cfa6a6480f6a5072a04d0fc592e 498 SUPERFAMILY SSF56801 3 493 2.09E-63 T 29-03-2018 SMALA_RS25255 b7b96cfa6a6480f6a5072a04d0fc592e 498 Gene3D G3DSA:3.30.300.30 407 498 5.7E-5 T 29-03-2018 SMALA_RS25255 b7b96cfa6a6480f6a5072a04d0fc592e 498 Gene3D G3DSA:2.30.38.10 319 393 1.1E-5 T 29-03-2018 SMALA_RS25255 b7b96cfa6a6480f6a5072a04d0fc592e 498 Pfam PF00501 AMP-binding enzyme 9 396 2.8E-45 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS25255 b7b96cfa6a6480f6a5072a04d0fc592e 498 Gene3D G3DSA:3.40.50.980 1 163 3.1E-22 T 29-03-2018 SMALA_RS25255 b7b96cfa6a6480f6a5072a04d0fc592e 498 Gene3D G3DSA:3.40.50.980 164 318 3.8E-25 T 29-03-2018 SMALA_RS19645 f75bc37fe4ee459b5d76f8412fa0fd2e 573 Gene3D G3DSA:3.30.200.20 23 172 6.8E-5 T 29-03-2018 SMALA_RS19645 f75bc37fe4ee459b5d76f8412fa0fd2e 573 Gene3D G3DSA:1.10.510.10 173 333 2.5E-5 T 29-03-2018 SMALA_RS19645 f75bc37fe4ee459b5d76f8412fa0fd2e 573 SUPERFAMILY SSF56112 93 247 3.12E-13 T 29-03-2018 IPR011009 Protein kinase-like domain SMALA_RS19645 f75bc37fe4ee459b5d76f8412fa0fd2e 573 Gene3D G3DSA:2.60.120.260 390 573 2.0E-6 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS12000 55efe912d4bf7d19d5abae2d7cf63234 343 Pfam PF00248 Aldo/keto reductase family 25 323 8.7E-68 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS12000 55efe912d4bf7d19d5abae2d7cf63234 343 Gene3D G3DSA:3.20.20.100 10 341 1.2E-93 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS12000 55efe912d4bf7d19d5abae2d7cf63234 343 SUPERFAMILY SSF51430 14 324 1.02E-89 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS16625 4121c03939237cf0a57867de4ad9c7cd 693 SUPERFAMILY SSF53448 326 579 1.23E-61 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS16625 4121c03939237cf0a57867de4ad9c7cd 693 SUPERFAMILY SSF88713 68 212 3.34E-30 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 SMALA_RS16625 4121c03939237cf0a57867de4ad9c7cd 693 Gene3D G3DSA:3.90.550.10 303 572 3.5E-64 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS16625 4121c03939237cf0a57867de4ad9c7cd 693 Gene3D G3DSA:3.20.20.370 62 281 8.8E-27 T 29-03-2018 SMALA_RS16625 4121c03939237cf0a57867de4ad9c7cd 693 Pfam PF01522 Polysaccharide deacetylase 75 183 2.4E-21 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 SMALA_RS16625 4121c03939237cf0a57867de4ad9c7cd 693 Pfam PF13641 Glycosyltransferase like family 2 328 547 5.6E-36 T 29-03-2018 SMALA_RS33265 4b0cac95ad57c45212e98538c0facb46 460 Pfam PF00860 Permease family 34 405 3.0E-65 T 29-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 SMALA_RS13380 baff81d19241fc524d733cea7d6f85bf 324 SUPERFAMILY SSF47240 14 318 7.22E-85 T 29-03-2018 IPR009078 Ferritin-like superfamily SMALA_RS13380 baff81d19241fc524d733cea7d6f85bf 324 PIRSF PIRSF000346 2 323 6.4E-113 T 29-03-2018 IPR005067 Fatty acid desaturase, type 2 GO:0006631|GO:0045300|GO:0055114 SMALA_RS13380 baff81d19241fc524d733cea7d6f85bf 324 Gene3D G3DSA:1.10.620.20 7 321 6.2E-106 T 29-03-2018 SMALA_RS13380 baff81d19241fc524d733cea7d6f85bf 324 Pfam PF03405 Fatty acid desaturase 17 312 5.4E-78 T 29-03-2018 IPR005067 Fatty acid desaturase, type 2 GO:0006631|GO:0045300|GO:0055114 SMALA_RS30720 1b6a1991f33d6064a5f8187df2f26a0c 250 PIRSF PIRSF006648 1 250 2.6E-43 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMALA_RS30720 1b6a1991f33d6064a5f8187df2f26a0c 250 Pfam PF01061 ABC-2 type transporter 9 214 5.1E-24 T 29-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 SMALA_RS23430 7de7e5c802b6ba5cbf767646dcbf901a 169 SUPERFAMILY SSF55729 2 163 1.66E-29 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS23430 7de7e5c802b6ba5cbf767646dcbf901a 169 Gene3D G3DSA:3.40.630.30 1 169 5.1E-30 T 29-03-2018 SMALA_RS23430 7de7e5c802b6ba5cbf767646dcbf901a 169 Pfam PF00583 Acetyltransferase (GNAT) family 40 139 2.9E-13 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SMALA_RS17065 47c2e1661469386cca3a8673af219322 441 Pfam PF09471 IgA Peptidase M64 91 342 8.0E-67 T 29-03-2018 IPR019026 Peptidase M64, IgA SMALA_RS17065 47c2e1661469386cca3a8673af219322 441 Gene3D G3DSA:2.60.40.10 347 427 2.2E-4 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS38100 698f96891bab9d58d816fac3f48ffdcc 267 Pfam PF04954 Siderophore-interacting protein 142 262 1.7E-35 T 29-03-2018 IPR007037 Siderophore-interacting protein SMALA_RS38100 698f96891bab9d58d816fac3f48ffdcc 267 Gene3D G3DSA:3.40.50.80 136 267 3.2E-43 T 29-03-2018 SMALA_RS38100 698f96891bab9d58d816fac3f48ffdcc 267 Gene3D G3DSA:2.40.30.10 6 132 3.3E-27 T 29-03-2018 SMALA_RS38100 698f96891bab9d58d816fac3f48ffdcc 267 Pfam PF08021 Siderophore-interacting FAD-binding domain 18 130 4.6E-29 T 29-03-2018 IPR013113 FAD-binding 9, siderophore-interacting SMALA_RS03050 558a630e45029be93994e61f4d69c313 82 Pfam PF17196 Protein of unknown function (DUF5133) 1 64 2.8E-28 T 29-03-2018 IPR033457 Protein of unknown function DUF5133 SMALA_RS36260 b1343167149cab277ecf3223bcdf525f 139 Gene3D G3DSA:3.30.750.24 13 111 5.2E-9 T 29-03-2018 IPR002645 STAS domain SMALA_RS36260 b1343167149cab277ecf3223bcdf525f 139 Pfam PF13466 STAS domain 17 98 1.0E-17 T 29-03-2018 IPR002645 STAS domain SMALA_RS36260 b1343167149cab277ecf3223bcdf525f 139 SUPERFAMILY SSF52091 15 102 3.92E-11 T 29-03-2018 IPR002645 STAS domain SMALA_RS29405 3c173d28d2dfabf14dd3ef6d220d510e 83 Gene3D G3DSA:1.10.1200.10 7 82 4.0E-14 T 29-03-2018 SMALA_RS29405 3c173d28d2dfabf14dd3ef6d220d510e 83 Pfam PF00550 Phosphopantetheine attachment site 11 75 2.1E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS29405 3c173d28d2dfabf14dd3ef6d220d510e 83 SUPERFAMILY SSF47336 7 80 6.81E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS13690 7383d4ead775e6a8efca0b45bf62eb33 257 Gene3D G3DSA:3.90.550.10 1 236 1.5E-42 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS13690 7383d4ead775e6a8efca0b45bf62eb33 257 Pfam PF00535 Glycosyl transferase family 2 5 133 6.6E-28 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 SMALA_RS13690 7383d4ead775e6a8efca0b45bf62eb33 257 SUPERFAMILY SSF53448 2 230 1.05E-49 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS19800 b8a46949c498db3d8c432c0cd9fb37d1 177 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 61 73 1.5E-27 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 SMALA_RS19800 b8a46949c498db3d8c432c0cd9fb37d1 177 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 116 128 1.5E-27 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 SMALA_RS19800 b8a46949c498db3d8c432c0cd9fb37d1 177 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 129 144 1.5E-27 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 SMALA_RS19800 b8a46949c498db3d8c432c0cd9fb37d1 177 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 20 35 1.5E-27 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 SMALA_RS19800 b8a46949c498db3d8c432c0cd9fb37d1 177 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 101 116 1.5E-27 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 SMALA_RS19800 b8a46949c498db3d8c432c0cd9fb37d1 177 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 56 73 - T 29-03-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 SMALA_RS19800 b8a46949c498db3d8c432c0cd9fb37d1 177 SUPERFAMILY SSF50891 6 171 8.04E-59 T 29-03-2018 IPR029000 Cyclophilin-like domain SMALA_RS19800 b8a46949c498db3d8c432c0cd9fb37d1 177 Gene3D G3DSA:2.40.100.10 1 176 6.6E-60 T 29-03-2018 IPR029000 Cyclophilin-like domain SMALA_RS19800 b8a46949c498db3d8c432c0cd9fb37d1 177 PIRSF PIRSF001467 2 176 1.1E-53 T 29-03-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 SMALA_RS19800 b8a46949c498db3d8c432c0cd9fb37d1 177 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 7 171 5.3E-43 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 SMALA_RS16615 ff8b0ec6860123ad9d440ec1d24164e4 389 Gene3D G3DSA:3.40.710.10 34 381 4.7E-64 T 29-03-2018 SMALA_RS16615 ff8b0ec6860123ad9d440ec1d24164e4 389 SUPERFAMILY SSF56601 45 356 2.13E-65 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMALA_RS16615 ff8b0ec6860123ad9d440ec1d24164e4 389 Pfam PF00144 Beta-lactamase 51 363 1.5E-52 T 29-03-2018 IPR001466 Beta-lactamase-related SMALA_RS04885 e79be4ccaf319d68fa730825cd732e8c 391 PRINTS PR00412 Epoxide hydrolase signature 194 207 3.3E-19 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS04885 e79be4ccaf319d68fa730825cd732e8c 391 PRINTS PR00412 Epoxide hydrolase signature 135 150 3.3E-19 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS04885 e79be4ccaf319d68fa730825cd732e8c 391 PRINTS PR00412 Epoxide hydrolase signature 106 124 3.3E-19 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS04885 e79be4ccaf319d68fa730825cd732e8c 391 PRINTS PR00412 Epoxide hydrolase signature 328 344 3.3E-19 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS04885 e79be4ccaf319d68fa730825cd732e8c 391 PRINTS PR00412 Epoxide hydrolase signature 359 381 3.3E-19 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS04885 e79be4ccaf319d68fa730825cd732e8c 391 PIRSF PIRSF001112 6 388 1.1E-108 T 29-03-2018 IPR016292 Epoxide hydrolase GO:0033961 KEGG: 00980+3.3.2.9|Reactome: R-HSA-211945 SMALA_RS04885 e79be4ccaf319d68fa730825cd732e8c 391 SUPERFAMILY SSF53474 4 384 9.53E-100 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS04885 e79be4ccaf319d68fa730825cd732e8c 391 Pfam PF06441 Epoxide hydrolase N terminus 9 114 1.4E-28 T 29-03-2018 IPR010497 Epoxide hydrolase, N-terminal KEGG: 00980+3.3.2.9|Reactome: R-HSA-211945 SMALA_RS04885 e79be4ccaf319d68fa730825cd732e8c 391 Gene3D G3DSA:3.40.50.1820 3 390 2.6E-82 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS28840 401cb3cfa88daab71fb1e250aa57af38 313 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 62 163 1.4E-17 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 SMALA_RS28840 401cb3cfa88daab71fb1e250aa57af38 313 Gene3D G3DSA:1.10.3720.10 19 279 1.1E-42 T 29-03-2018 SMALA_RS28840 401cb3cfa88daab71fb1e250aa57af38 313 SUPERFAMILY SSF161098 63 259 1.57E-39 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS28840 401cb3cfa88daab71fb1e250aa57af38 313 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 82 272 1.0E-23 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS35300 725aad8714030423b94496359e98b94b 83 Gene3D G3DSA:1.10.287.130 17 63 7.9E-5 T 29-03-2018 SMALA_RS35300 725aad8714030423b94496359e98b94b 83 Pfam PF05120 Gas vesicle protein G 7 72 5.6E-19 T 29-03-2018 IPR007804 Gas vesicle protein GvpG SMALA_RS22620 5535f111f092df28fcc6db3e3e69d26d 127 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 13 127 26.867 T 29-03-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS22620 5535f111f092df28fcc6db3e3e69d26d 127 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 13 127 1.4E-48 T 29-03-2018 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS22620 5535f111f092df28fcc6db3e3e69d26d 127 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 16 127 2.5E-38 T 29-03-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS22620 5535f111f092df28fcc6db3e3e69d26d 127 Gene3D G3DSA:3.30.420.100 1 127 2.6E-38 T 29-03-2018 SMALA_RS22620 5535f111f092df28fcc6db3e3e69d26d 127 SUPERFAMILY SSF53137 14 125 1.96E-46 T 29-03-2018 SMALA_RS01840 d10c1e74626a0d013364f07a09aaf3ed 201 Gene3D G3DSA:1.10.3630.10 1 199 1.2E-40 T 29-03-2018 SMALA_RS01840 d10c1e74626a0d013364f07a09aaf3ed 201 Pfam PF05719 Golgi phosphoprotein 3 (GPP34) 5 190 3.8E-20 T 29-03-2018 IPR008628 Golgi phosphoprotein 3-like GO:0070273 SMALA_RS30890 bd3b36ffbe2c628cf53b1adf65ffa89e 470 Pfam PF00107 Zinc-binding dehydrogenase 236 380 1.1E-38 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMALA_RS30890 bd3b36ffbe2c628cf53b1adf65ffa89e 470 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 115 189 4.0E-5 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS30890 bd3b36ffbe2c628cf53b1adf65ffa89e 470 Gene3D G3DSA:3.40.50.720 234 347 5.1E-20 T 29-03-2018 SMALA_RS30890 bd3b36ffbe2c628cf53b1adf65ffa89e 470 Gene3D G3DSA:3.90.180.10 348 417 0.11 T 29-03-2018 SMALA_RS30890 bd3b36ffbe2c628cf53b1adf65ffa89e 470 SMART SM00829 49 415 2.6E-10 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS30890 bd3b36ffbe2c628cf53b1adf65ffa89e 470 TIGRFAM TIGR01751 crot-CoA-red: crotonyl-CoA carboxylase/reductase 31 427 4.7E-187 T 29-03-2018 IPR010085 Crotonyl-CoA reductase GO:0043880 KEGG: 00650+1.3.1.86 SMALA_RS30890 bd3b36ffbe2c628cf53b1adf65ffa89e 470 SUPERFAMILY SSF51735 198 393 1.73E-37 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS30890 bd3b36ffbe2c628cf53b1adf65ffa89e 470 Gene3D G3DSA:3.90.180.10 10 233 4.7E-37 T 29-03-2018 SMALA_RS30890 bd3b36ffbe2c628cf53b1adf65ffa89e 470 SUPERFAMILY SSF50129 49 230 1.98E-26 T 29-03-2018 IPR011032 GroES-like SMALA_RS09155 3682fe657758154058eff42dae757807 375 Gene3D G3DSA:3.40.50.1820 132 373 3.7E-26 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS09155 3682fe657758154058eff42dae757807 375 SUPERFAMILY SSF53474 306 371 1.65E-26 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS09155 3682fe657758154058eff42dae757807 375 SUPERFAMILY SSF53474 130 268 1.65E-26 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS17535 6244dc274c193ed91c7411262efe0f81 72 Gene3D G3DSA:1.10.10.10 1 72 2.4E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS17535 6244dc274c193ed91c7411262efe0f81 72 Pfam PF11662 Protein of unknown function (DUF3263) 1 72 9.7E-34 T 29-03-2018 IPR021678 Protein of unknown function DUF3263 SMALA_RS03175 a0b6b2dd0638bbd3a55d2bfd2b17a1be 146 Gene3D G3DSA:3.10.180.10 1 146 3.5E-27 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS03175 a0b6b2dd0638bbd3a55d2bfd2b17a1be 146 SUPERFAMILY SSF54593 3 143 1.79E-31 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS03175 a0b6b2dd0638bbd3a55d2bfd2b17a1be 146 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 118 1.5E-10 T 29-03-2018 SMALA_RS38390 dab374956042743b76a6dff1df99548b 299 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 1 114 1.4E-21 T 29-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 SMALA_RS38390 dab374956042743b76a6dff1df99548b 299 Gene3D G3DSA:3.30.360.10 134 298 5.1E-16 T 29-03-2018 SMALA_RS38390 dab374956042743b76a6dff1df99548b 299 Gene3D G3DSA:3.40.50.720 1 133 1.1E-32 T 29-03-2018 SMALA_RS38390 dab374956042743b76a6dff1df99548b 299 SUPERFAMILY SSF51735 1 131 3.16E-34 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS38390 dab374956042743b76a6dff1df99548b 299 SUPERFAMILY SSF55347 153 242 6.38E-10 T 29-03-2018 SMALA_RS39340 e20ccbc42500ce604d966056b3341cb5 178 SUPERFAMILY SSF55729 9 164 2.4E-21 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS39340 e20ccbc42500ce604d966056b3341cb5 178 Pfam PF00583 Acetyltransferase (GNAT) family 58 157 1.2E-9 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SMALA_RS39340 e20ccbc42500ce604d966056b3341cb5 178 Gene3D G3DSA:3.40.630.30 3 176 5.3E-23 T 29-03-2018 SMALA_RS10125 85dd0f30e91ac46cf77c5fa765fbf73e 441 SUPERFAMILY SSF56112 40 149 3.06E-8 T 29-03-2018 IPR011009 Protein kinase-like domain SMALA_RS10125 85dd0f30e91ac46cf77c5fa765fbf73e 441 Pfam PF10009 Uncharacterized protein conserved in bacteria (DUF2252) 30 431 3.8E-121 T 29-03-2018 IPR018721 Protein of unknown function DUF2252 SMALA_RS10125 85dd0f30e91ac46cf77c5fa765fbf73e 441 Gene3D G3DSA:1.10.510.10 5 152 5.4E-9 T 29-03-2018 SMALA_RS37760 b28ad72738cb760f3f784e919ac5cbec 677 TIGRFAM TIGR01634 tail_P2_I: phage tail protein I 400 480 6.1E-8 T 29-03-2018 IPR006521 Tail protein I SMALA_RS37760 b28ad72738cb760f3f784e919ac5cbec 677 Gene3D G3DSA:2.120.10.30 44 321 3.8E-8 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like SMALA_RS37760 b28ad72738cb760f3f784e919ac5cbec 677 Pfam PF09684 Phage tail protein (Tail_P2_I) 400 503 6.1E-16 T 29-03-2018 IPR006521 Tail protein I SMALA_RS37760 b28ad72738cb760f3f784e919ac5cbec 677 SUPERFAMILY SSF63825 72 207 2.51E-8 T 29-03-2018 SMALA_RS37760 b28ad72738cb760f3f784e919ac5cbec 677 TIGRFAM TIGR02242 tail_TIGR02242: phage tail protein domain 377 485 1.5E-23 T 29-03-2018 IPR011748 Uncharacterised protein family, phage tail-like SMALA_RS22615 0570b5f549e28b46dd83c8b22d29deb3 179 Pfam PF00347 Ribosomal protein L6 11 83 5.4E-19 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMALA_RS22615 0570b5f549e28b46dd83c8b22d29deb3 179 Pfam PF00347 Ribosomal protein L6 92 165 1.2E-20 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMALA_RS22615 0570b5f549e28b46dd83c8b22d29deb3 179 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 177 1.2E-74 T 29-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 SMALA_RS22615 0570b5f549e28b46dd83c8b22d29deb3 179 Gene3D G3DSA:3.90.930.12 2 83 9.5E-29 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMALA_RS22615 0570b5f549e28b46dd83c8b22d29deb3 179 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 155 163 - T 29-03-2018 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS22615 0570b5f549e28b46dd83c8b22d29deb3 179 SUPERFAMILY SSF56053 1 83 1.57E-26 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMALA_RS22615 0570b5f549e28b46dd83c8b22d29deb3 179 PRINTS PR00059 Ribosomal protein L6 signature 72 97 2.3E-32 T 29-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 SMALA_RS22615 0570b5f549e28b46dd83c8b22d29deb3 179 PRINTS PR00059 Ribosomal protein L6 signature 100 116 2.3E-32 T 29-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 SMALA_RS22615 0570b5f549e28b46dd83c8b22d29deb3 179 PRINTS PR00059 Ribosomal protein L6 signature 142 163 2.3E-32 T 29-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 SMALA_RS22615 0570b5f549e28b46dd83c8b22d29deb3 179 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 177 38.793 T 29-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 SMALA_RS22615 0570b5f549e28b46dd83c8b22d29deb3 179 PIRSF PIRSF002162 1 178 5.0E-49 T 29-03-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMALA_RS22615 0570b5f549e28b46dd83c8b22d29deb3 179 Gene3D G3DSA:3.90.930.12 84 179 1.2E-38 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMALA_RS22615 0570b5f549e28b46dd83c8b22d29deb3 179 SUPERFAMILY SSF56053 84 177 1.56E-35 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMALA_RS13230 391347403bcb739e2d7bab294ed01f4f 218 Gene3D G3DSA:3.90.226.10 25 208 5.8E-42 T 29-03-2018 SMALA_RS13230 391347403bcb739e2d7bab294ed01f4f 218 Pfam PF00574 Clp protease 34 206 3.1E-78 T 29-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA SMALA_RS13230 391347403bcb739e2d7bab294ed01f4f 218 SUPERFAMILY SSF52096 34 207 2.84E-67 T 29-03-2018 IPR029045 ClpP/crotonase-like domain SMALA_RS13230 391347403bcb739e2d7bab294ed01f4f 218 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 126 139 - T 29-03-2018 IPR033135 ClpP, histidine active site SMALA_RS13230 391347403bcb739e2d7bab294ed01f4f 218 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 18 207 40.413 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMALA_RS13230 391347403bcb739e2d7bab294ed01f4f 218 PRINTS PR00127 Clp protease catalytic subunit P signature 125 144 7.2E-49 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMALA_RS13230 391347403bcb739e2d7bab294ed01f4f 218 PRINTS PR00127 Clp protease catalytic subunit P signature 34 49 7.2E-49 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMALA_RS13230 391347403bcb739e2d7bab294ed01f4f 218 PRINTS PR00127 Clp protease catalytic subunit P signature 73 93 7.2E-49 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMALA_RS13230 391347403bcb739e2d7bab294ed01f4f 218 PRINTS PR00127 Clp protease catalytic subunit P signature 104 121 7.2E-49 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMALA_RS13230 391347403bcb739e2d7bab294ed01f4f 218 PRINTS PR00127 Clp protease catalytic subunit P signature 182 201 7.2E-49 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMALA_RS39060 b3b44215928bfd3525a79c1b5dfe1a1c 369 Gene3D G3DSA:3.20.20.30 20 347 3.1E-44 T 29-03-2018 SMALA_RS39060 b3b44215928bfd3525a79c1b5dfe1a1c 369 TIGRFAM TIGR03841 F420_Rv3093c: probable F420-dependent oxidoreductase, Rv3093c family 28 324 2.0E-103 T 29-03-2018 IPR022526 F420-dependent oxidoreductase, Rv3093c SMALA_RS39060 b3b44215928bfd3525a79c1b5dfe1a1c 369 SUPERFAMILY SSF51679 24 335 9.76E-41 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS39060 b3b44215928bfd3525a79c1b5dfe1a1c 369 Pfam PF00296 Luciferase-like monooxygenase 39 318 4.1E-39 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS37515 8d769a8d6c0226c898e1a06da80fc8a3 251 Hamap MF_02036 Gamma-glutamyl-hercynylcysteine sulfoxide hydrolase [egtC]. 1 246 41.426 T 29-03-2018 IPR032889 Gamma-glutamyl-hercynylcysteine sulfoxide hydrolase, Actinobacteria GO:0016811|GO:0052699 SMALA_RS37515 8d769a8d6c0226c898e1a06da80fc8a3 251 Pfam PF13522 Glutamine amidotransferase domain 71 217 3.2E-18 T 29-03-2018 SMALA_RS37515 8d769a8d6c0226c898e1a06da80fc8a3 251 Gene3D G3DSA:3.60.20.10 206 247 0.15 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SMALA_RS37515 8d769a8d6c0226c898e1a06da80fc8a3 251 Gene3D G3DSA:3.60.20.10 1 205 4.6E-29 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SMALA_RS37515 8d769a8d6c0226c898e1a06da80fc8a3 251 TIGRFAM TIGR03442 TIGR03442: ergothioneine biosynthesis protein EgtC 1 246 2.6E-90 T 29-03-2018 IPR017808 Ergothioneine biosynthesis protein EgtC GO:0052699 SMALA_RS37515 8d769a8d6c0226c898e1a06da80fc8a3 251 SUPERFAMILY SSF56235 2 243 4.79E-20 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SMALA_RS08215 da0ef556c8a5fe82c0aba916d803fb4c 539 Gene3D G3DSA:3.30.300.30 442 533 3.7E-6 T 29-03-2018 SMALA_RS08215 da0ef556c8a5fe82c0aba916d803fb4c 539 ProSitePatterns PS00455 Putative AMP-binding domain signature. 181 192 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS08215 da0ef556c8a5fe82c0aba916d803fb4c 539 Gene3D G3DSA:3.40.50.980 186 344 1.6E-17 T 29-03-2018 SMALA_RS08215 da0ef556c8a5fe82c0aba916d803fb4c 539 Gene3D G3DSA:2.30.38.10 363 435 3.7E-11 T 29-03-2018 SMALA_RS08215 da0ef556c8a5fe82c0aba916d803fb4c 539 Pfam PF00501 AMP-binding enzyme 37 440 9.9E-45 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS08215 da0ef556c8a5fe82c0aba916d803fb4c 539 SUPERFAMILY SSF56801 30 528 5.23E-61 T 29-03-2018 SMALA_RS08215 da0ef556c8a5fe82c0aba916d803fb4c 539 Gene3D G3DSA:3.40.50.980 46 185 2.0E-22 T 29-03-2018 SMALA_RS40925 7bb504de0343ab76b00ea4fbbc7ea7c1 72 SUPERFAMILY SSF160582 1 69 2.48E-33 T 29-03-2018 SMALA_RS40925 7bb504de0343ab76b00ea4fbbc7ea7c1 72 SMART SM00923 3 53 3.8E-34 T 29-03-2018 IPR005153 MbtH-like protein SMALA_RS40925 7bb504de0343ab76b00ea4fbbc7ea7c1 72 Pfam PF03621 MbtH-like protein 1 53 1.1E-30 T 29-03-2018 IPR005153 MbtH-like protein SMALA_RS40925 7bb504de0343ab76b00ea4fbbc7ea7c1 72 Gene3D G3DSA:3.90.820.10 2 68 9.8E-38 T 29-03-2018 SMALA_RS08740 040a75e97b471b04e7a1e124e606312f 384 Gene3D G3DSA:3.40.50.2000 188 351 3.2E-37 T 29-03-2018 SMALA_RS08740 040a75e97b471b04e7a1e124e606312f 384 SUPERFAMILY SSF53756 26 370 3.53E-63 T 29-03-2018 SMALA_RS08740 040a75e97b471b04e7a1e124e606312f 384 Pfam PF00534 Glycosyl transferases group 1 189 348 3.5E-26 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 SMALA_RS08740 040a75e97b471b04e7a1e124e606312f 384 Pfam PF13579 Glycosyl transferase 4-like domain 27 172 2.2E-19 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 SMALA_RS08740 040a75e97b471b04e7a1e124e606312f 384 Gene3D G3DSA:3.40.50.2000 13 187 7.9E-12 T 29-03-2018 SMALA_RS08845 90f4ecdbd017618a469fa36437e53d3f 167 Gene3D G3DSA:3.40.1800.10 64 137 9.5E-17 T 29-03-2018 SMALA_RS08845 90f4ecdbd017618a469fa36437e53d3f 167 SMART SM00507 71 120 1.4E-11 T 29-03-2018 IPR003615 HNH nuclease SMALA_RS08845 90f4ecdbd017618a469fa36437e53d3f 167 Pfam PF14279 HNH endonuclease 84 134 2.5E-10 T 29-03-2018 IPR029471 HNH endonuclease 5 SMALA_RS02040 0ad1ed0ab4b16eec3c68f1eea5daf75e 251 Gene3D G3DSA:2.60.200.20 12 88 3.8E-4 T 29-03-2018 SMALA_RS02040 0ad1ed0ab4b16eec3c68f1eea5daf75e 251 SUPERFAMILY SSF49879 30 80 4.97E-6 T 29-03-2018 IPR008984 SMAD/FHA domain GO:0005515 SMALA_RS17090 7809b5fc926481185a94c7d38a7a0d0f 125 Gene3D G3DSA:3.30.750.24 2 112 1.9E-28 T 29-03-2018 IPR002645 STAS domain SMALA_RS17090 7809b5fc926481185a94c7d38a7a0d0f 125 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 5 105 2.7E-17 T 29-03-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 SMALA_RS17090 7809b5fc926481185a94c7d38a7a0d0f 125 Pfam PF13466 STAS domain 11 81 2.2E-12 T 29-03-2018 IPR002645 STAS domain SMALA_RS17090 7809b5fc926481185a94c7d38a7a0d0f 125 SUPERFAMILY SSF52091 4 110 5.1E-22 T 29-03-2018 IPR002645 STAS domain SMALA_RS41620 b5bfbc56b6e014af1a1b73548e6a5916 368 Pfam PF02653 Branched-chain amino acid transport system / permease component 74 331 5.1E-38 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 SMALA_RS41620 b5bfbc56b6e014af1a1b73548e6a5916 368 Gene3D G3DSA:1.10.3470.10 60 337 4.0E-32 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SMALA_RS05460 9b2eeb09b0e9ec920aafa481973b354c 105 Pfam PF03992 Antibiotic biosynthesis monooxygenase 8 81 4.6E-8 T 29-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain SMALA_RS05460 9b2eeb09b0e9ec920aafa481973b354c 105 SUPERFAMILY SSF54909 5 94 2.39E-12 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel SMALA_RS05460 9b2eeb09b0e9ec920aafa481973b354c 105 Gene3D G3DSA:3.30.70.100 5 105 7.2E-16 T 29-03-2018 SMALA_RS32290 72d15537f373be49fe2670b4a011dad6 266 Pfam PF00230 Major intrinsic protein 3 219 1.2E-46 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMALA_RS32290 72d15537f373be49fe2670b4a011dad6 266 SUPERFAMILY SSF81338 4 223 1.13E-54 T 29-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 SMALA_RS32290 72d15537f373be49fe2670b4a011dad6 266 ProSitePatterns PS00221 MIP family signature. 58 66 - T 29-03-2018 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMALA_RS32290 72d15537f373be49fe2670b4a011dad6 266 PRINTS PR00783 Major intrinsic protein family signature 133 151 1.4E-50 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMALA_RS32290 72d15537f373be49fe2670b4a011dad6 266 PRINTS PR00783 Major intrinsic protein family signature 77 96 1.4E-50 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMALA_RS32290 72d15537f373be49fe2670b4a011dad6 266 PRINTS PR00783 Major intrinsic protein family signature 4 23 1.4E-50 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMALA_RS32290 72d15537f373be49fe2670b4a011dad6 266 PRINTS PR00783 Major intrinsic protein family signature 202 222 1.4E-50 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMALA_RS32290 72d15537f373be49fe2670b4a011dad6 266 PRINTS PR00783 Major intrinsic protein family signature 163 185 1.4E-50 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMALA_RS32290 72d15537f373be49fe2670b4a011dad6 266 PRINTS PR00783 Major intrinsic protein family signature 40 64 1.4E-50 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMALA_RS32290 72d15537f373be49fe2670b4a011dad6 266 Gene3D G3DSA:1.20.1080.10 2 225 7.7E-57 T 29-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 SMALA_RS07165 251e10458770e5f2dbe8322b0ef18ed0 303 SMART SM00475 1 274 7.7E-76 T 29-03-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 SMALA_RS07165 251e10458770e5f2dbe8322b0ef18ed0 303 SUPERFAMILY SSF88723 1 162 3.92E-37 T 29-03-2018 IPR029060 PIN domain-like SMALA_RS07165 251e10458770e5f2dbe8322b0ef18ed0 303 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 183 265 2.5E-17 T 29-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 SMALA_RS07165 251e10458770e5f2dbe8322b0ef18ed0 303 Gene3D G3DSA:3.40.50.1010 1 189 9.1E-56 T 29-03-2018 IPR029060 PIN domain-like SMALA_RS07165 251e10458770e5f2dbe8322b0ef18ed0 303 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 1 179 9.3E-48 T 29-03-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 SMALA_RS07165 251e10458770e5f2dbe8322b0ef18ed0 303 SUPERFAMILY SSF47807 185 296 7.18E-19 T 29-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 SMALA_RS07165 251e10458770e5f2dbe8322b0ef18ed0 303 SMART SM00279 182 217 3.9E-10 T 29-03-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 SMALA_RS07165 251e10458770e5f2dbe8322b0ef18ed0 303 Gene3D G3DSA:1.10.150.20 190 256 3.1E-18 T 29-03-2018 SMALA_RS32700 251a23939f2507b5c4a65d6ca8dac662 111 Gene3D G3DSA:1.10.10.10 6 92 1.6E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS32700 251a23939f2507b5c4a65d6ca8dac662 111 SMART SM00418 18 98 0.001 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS32700 251a23939f2507b5c4a65d6ca8dac662 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 54 69 6.8E-6 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS32700 251a23939f2507b5c4a65d6ca8dac662 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 20 35 6.8E-6 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS32700 251a23939f2507b5c4a65d6ca8dac662 111 Pfam PF12840 Helix-turn-helix domain 19 73 3.0E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS32700 251a23939f2507b5c4a65d6ca8dac662 111 SUPERFAMILY SSF46785 8 99 2.72E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS41335 e3e0b925adb2286c484c83be47c48134 415 SUPERFAMILY SSF51905 12 63 1.29E-39 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS41335 e3e0b925adb2286c484c83be47c48134 415 SUPERFAMILY SSF51905 124 273 1.29E-39 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS41335 e3e0b925adb2286c484c83be47c48134 415 SUPERFAMILY SSF51905 360 415 1.29E-39 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS41335 e3e0b925adb2286c484c83be47c48134 415 SUPERFAMILY SSF54373 273 359 6.41E-9 T 29-03-2018 SMALA_RS41335 e3e0b925adb2286c484c83be47c48134 415 Pfam PF01266 FAD dependent oxidoreductase 12 397 3.2E-55 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 SMALA_RS41335 e3e0b925adb2286c484c83be47c48134 415 Gene3D G3DSA:3.50.50.60 3 415 2.0E-45 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS04975 cb14a440fd48335921874045c7865bfa 260 Pfam PF08787 Alginate lyase 47 259 3.1E-45 T 29-03-2018 IPR014895 Alginate lyase 2 SMALA_RS04975 cb14a440fd48335921874045c7865bfa 260 SUPERFAMILY SSF49899 39 260 6.73E-67 T 29-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain SMALA_RS04975 cb14a440fd48335921874045c7865bfa 260 Gene3D G3DSA:2.60.120.200 37 260 1.5E-62 T 29-03-2018 SMALA_RS18625 b32cc5e946cfd9c458cca3d281405474 220 Pfam PF00293 NUDIX domain 40 160 1.5E-11 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SMALA_RS18625 b32cc5e946cfd9c458cca3d281405474 220 SUPERFAMILY SSF55811 28 198 1.26E-25 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMALA_RS18625 b32cc5e946cfd9c458cca3d281405474 220 Gene3D G3DSA:3.90.79.10 19 203 2.4E-33 T 29-03-2018 SMALA_RS25480 bf029f269a7d7cc0ca1ba19c5ce60d6a 245 Pfam PF12710 haloacid dehalogenase-like hydrolase 5 182 8.3E-11 T 29-03-2018 SMALA_RS25480 bf029f269a7d7cc0ca1ba19c5ce60d6a 245 SUPERFAMILY SSF56784 1 222 1.07E-25 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS25480 bf029f269a7d7cc0ca1ba19c5ce60d6a 245 Gene3D G3DSA:1.10.150.240 20 72 2.5E-6 T 29-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 SMALA_RS25480 bf029f269a7d7cc0ca1ba19c5ce60d6a 245 Gene3D G3DSA:3.40.50.1000 73 228 4.7E-17 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS38860 620c81cd2c24723827c404a7dd5275e1 146 SUPERFAMILY SSF51182 45 136 4.46E-9 T 29-03-2018 IPR011051 RmlC-like cupin domain SMALA_RS38860 620c81cd2c24723827c404a7dd5275e1 146 Gene3D G3DSA:2.60.120.10 36 137 1.3E-11 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SMALA_RS11385 297f487650cacf5dc60bc9aa017f0e81 284 Gene3D G3DSA:3.10.129.10 12 159 3.1E-41 T 29-03-2018 SMALA_RS11385 297f487650cacf5dc60bc9aa017f0e81 284 Gene3D G3DSA:3.10.129.10 160 281 8.8E-30 T 29-03-2018 SMALA_RS11385 297f487650cacf5dc60bc9aa017f0e81 284 SUPERFAMILY SSF54637 11 158 7.33E-37 T 29-03-2018 IPR029069 HotDog domain SMALA_RS11385 297f487650cacf5dc60bc9aa017f0e81 284 Pfam PF13452 N-terminal half of MaoC dehydratase 16 132 5.6E-14 T 29-03-2018 SMALA_RS11385 297f487650cacf5dc60bc9aa017f0e81 284 Pfam PF01575 MaoC like domain 161 263 5.2E-34 T 29-03-2018 IPR002539 MaoC-like domain SMALA_RS11385 297f487650cacf5dc60bc9aa017f0e81 284 SUPERFAMILY SSF54637 160 279 5.6E-32 T 29-03-2018 IPR029069 HotDog domain SMALA_RS31360 38415e46d136e3b1a16df74504951229 396 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 150 274 5.4E-10 T 29-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 SMALA_RS31360 38415e46d136e3b1a16df74504951229 396 SUPERFAMILY SSF55347 144 313 9.48E-36 T 29-03-2018 SMALA_RS31360 38415e46d136e3b1a16df74504951229 396 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 10 133 5.1E-23 T 29-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 SMALA_RS31360 38415e46d136e3b1a16df74504951229 396 Gene3D G3DSA:3.40.50.720 1 150 3.7E-38 T 29-03-2018 SMALA_RS31360 38415e46d136e3b1a16df74504951229 396 Gene3D G3DSA:3.30.360.10 151 392 3.2E-53 T 29-03-2018 SMALA_RS31360 38415e46d136e3b1a16df74504951229 396 SUPERFAMILY SSF51735 6 170 2.48E-47 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS40390 57aebd132cc02ff4b37860e28162f08e 366 Pfam PF11175 Protein of unknown function (DUF2961) 86 347 1.4E-84 T 29-03-2018 IPR021345 Protein of unknown function DUF2961 SMALA_RS05430 fb8c1922e3d1b5f1e88a587fa3c90108 139 Pfam PF03795 YCII-related domain 17 107 1.5E-11 T 29-03-2018 IPR005545 YCII-related SMALA_RS05430 fb8c1922e3d1b5f1e88a587fa3c90108 139 SUPERFAMILY SSF54909 21 125 6.17E-23 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel SMALA_RS05430 fb8c1922e3d1b5f1e88a587fa3c90108 139 Gene3D G3DSA:3.30.70.1060 1 131 1.1E-43 T 29-03-2018 SMALA_RS30410 12c8e71dd6f1e2e2c49114aba5a38186 294 Pfam PF00535 Glycosyl transferase family 2 12 163 1.5E-10 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 SMALA_RS30410 12c8e71dd6f1e2e2c49114aba5a38186 294 SUPERFAMILY SSF53448 6 248 6.56E-36 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS30410 12c8e71dd6f1e2e2c49114aba5a38186 294 Gene3D G3DSA:3.90.550.10 2 258 4.4E-29 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS25995 7a033e9e34e5ef8cc2fa9ef406cfd011 1100 SUPERFAMILY SSF52980 866 1006 2.14E-5 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 SMALA_RS25995 7a033e9e34e5ef8cc2fa9ef406cfd011 1100 Pfam PF13361 UvrD-like helicase C-terminal domain 561 731 7.1E-21 T 29-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 SMALA_RS25995 7a033e9e34e5ef8cc2fa9ef406cfd011 1100 Gene3D G3DSA:3.40.50.300 337 445 1.1E-9 T 29-03-2018 SMALA_RS25995 7a033e9e34e5ef8cc2fa9ef406cfd011 1100 SUPERFAMILY SSF52540 39 747 9.77E-106 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS25995 7a033e9e34e5ef8cc2fa9ef406cfd011 1100 Gene3D G3DSA:3.40.50.300 39 331 3.3E-52 T 29-03-2018 SMALA_RS25995 7a033e9e34e5ef8cc2fa9ef406cfd011 1100 Pfam PF00580 UvrD/REP helicase N-terminal domain 43 322 9.4E-51 T 29-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 SMALA_RS25995 7a033e9e34e5ef8cc2fa9ef406cfd011 1100 Gene3D G3DSA:3.90.320.10 755 1010 1.6E-16 T 29-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 SMALA_RS25995 7a033e9e34e5ef8cc2fa9ef406cfd011 1100 Pfam PF12705 PD-(D/E)XK nuclease superfamily 837 1089 1.2E-37 T 29-03-2018 SMALA_RS25995 7a033e9e34e5ef8cc2fa9ef406cfd011 1100 Gene3D G3DSA:3.40.50.300 493 754 5.2E-34 T 29-03-2018 SMALA_RS21895 00167c3adf1a1f16d4e550b1935e5e8a 412 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 351 360 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMALA_RS21895 00167c3adf1a1f16d4e550b1935e5e8a 412 PRINTS PR00359 B-class P450 signature 200 222 6.8E-52 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS21895 00167c3adf1a1f16d4e550b1935e5e8a 412 PRINTS PR00359 B-class P450 signature 358 369 6.8E-52 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS21895 00167c3adf1a1f16d4e550b1935e5e8a 412 PRINTS PR00359 B-class P450 signature 282 293 6.8E-52 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS21895 00167c3adf1a1f16d4e550b1935e5e8a 412 PRINTS PR00359 B-class P450 signature 152 167 6.8E-52 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS21895 00167c3adf1a1f16d4e550b1935e5e8a 412 PRINTS PR00359 B-class P450 signature 328 343 6.8E-52 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS21895 00167c3adf1a1f16d4e550b1935e5e8a 412 PRINTS PR00359 B-class P450 signature 349 358 6.8E-52 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS21895 00167c3adf1a1f16d4e550b1935e5e8a 412 PRINTS PR00359 B-class P450 signature 135 151 6.8E-52 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS21895 00167c3adf1a1f16d4e550b1935e5e8a 412 PRINTS PR00359 B-class P450 signature 85 96 6.8E-52 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS21895 00167c3adf1a1f16d4e550b1935e5e8a 412 PRINTS PR00359 B-class P450 signature 300 327 6.8E-52 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS21895 00167c3adf1a1f16d4e550b1935e5e8a 412 Gene3D G3DSA:1.10.630.10 2 409 1.1E-76 T 29-03-2018 SMALA_RS21895 00167c3adf1a1f16d4e550b1935e5e8a 412 SUPERFAMILY SSF48264 13 405 2.88E-89 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS21895 00167c3adf1a1f16d4e550b1935e5e8a 412 Pfam PF00067 Cytochrome P450 90 402 2.2E-32 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS21895 00167c3adf1a1f16d4e550b1935e5e8a 412 PRINTS PR00385 P450 superfamily signature 349 358 2.4E-6 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS21895 00167c3adf1a1f16d4e550b1935e5e8a 412 PRINTS PR00385 P450 superfamily signature 282 293 2.4E-6 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS21895 00167c3adf1a1f16d4e550b1935e5e8a 412 PRINTS PR00385 P450 superfamily signature 247 264 2.4E-6 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS21895 00167c3adf1a1f16d4e550b1935e5e8a 412 PRINTS PR00385 P450 superfamily signature 358 369 2.4E-6 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS15935 baf42f0e9256d7e2f2016a78a010dfb1 484 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 101 253 9.4E-48 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain SMALA_RS15935 baf42f0e9256d7e2f2016a78a010dfb1 484 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 363 448 2.5E-12 T 29-03-2018 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain SMALA_RS15935 baf42f0e9256d7e2f2016a78a010dfb1 484 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 101 253 1.3E-46 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain SMALA_RS16715 d13ede0008cb781a640afac3a0cd6952 544 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 201 439 4.6E-34 T 29-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 SMALA_RS16715 d13ede0008cb781a640afac3a0cd6952 544 SUPERFAMILY SSF56601 195 460 2.17E-43 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMALA_RS16715 d13ede0008cb781a640afac3a0cd6952 544 SUPERFAMILY SSF56601 145 155 2.17E-43 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMALA_RS16715 d13ede0008cb781a640afac3a0cd6952 544 Pfam PF17199 Protein of unknown function (DUF5136) 46 75 5.7E-20 T 29-03-2018 SMALA_RS16715 d13ede0008cb781a640afac3a0cd6952 544 Gene3D G3DSA:3.40.710.10 130 499 2.5E-39 T 29-03-2018 SMALA_RS42560 17d851e5801e851df39a7c7fa9ab33fa 323 SUPERFAMILY SSF161098 95 291 1.11E-13 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS42560 17d851e5801e851df39a7c7fa9ab33fa 323 Gene3D G3DSA:1.10.3720.10 3 297 3.3E-32 T 29-03-2018 SMALA_RS42560 17d851e5801e851df39a7c7fa9ab33fa 323 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 119 308 6.4E-28 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS11175 36f1c768412f923e9d200ea2bad9e765 338 SUPERFAMILY SSF55347 135 297 9.65E-43 T 29-03-2018 SMALA_RS11175 36f1c768412f923e9d200ea2bad9e765 338 SUPERFAMILY SSF51735 10 161 5.16E-49 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS11175 36f1c768412f923e9d200ea2bad9e765 338 Gene3D G3DSA:3.40.50.720 7 152 1.2E-46 T 29-03-2018 SMALA_RS11175 36f1c768412f923e9d200ea2bad9e765 338 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 11 126 5.5E-23 T 29-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 SMALA_RS11175 36f1c768412f923e9d200ea2bad9e765 338 Gene3D G3DSA:3.30.360.10 153 333 1.7E-41 T 29-03-2018 SMALA_RS12520 6903268c22753c749696de86724b27a5 274 Gene3D G3DSA:3.40.1080.10 3 245 6.2E-55 T 29-03-2018 SMALA_RS12520 6903268c22753c749696de86724b27a5 274 Pfam PF01144 Coenzyme A transferase 6 222 2.2E-25 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 SMALA_RS12520 6903268c22753c749696de86724b27a5 274 SMART SM00882 4 224 2.7E-43 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 SMALA_RS12520 6903268c22753c749696de86724b27a5 274 SUPERFAMILY SSF100950 5 268 6.09E-77 T 29-03-2018 SMALA_RS30810 ac2e0198cf8fa19c60c607577bbe16c1 740 Gene3D G3DSA:2.40.10.10 5 115 1.0E-5 T 29-03-2018 SMALA_RS30810 ac2e0198cf8fa19c60c607577bbe16c1 740 SUPERFAMILY SSF50494 21 213 1.02E-13 T 29-03-2018 IPR009003 Peptidase S1, PA clan SMALA_RS30810 ac2e0198cf8fa19c60c607577bbe16c1 740 Pfam PF13365 Trypsin-like peptidase domain 27 185 3.0E-9 T 29-03-2018 SMALA_RS30810 ac2e0198cf8fa19c60c607577bbe16c1 740 Gene3D G3DSA:2.40.10.10 132 216 4.0E-4 T 29-03-2018 SMALA_RS24025 d4230c0a0d2e3ea591b4b1b0d980229d 236 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 67 90 2.3E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS24025 d4230c0a0d2e3ea591b4b1b0d980229d 236 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 59 2.3E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS24025 d4230c0a0d2e3ea591b4b1b0d980229d 236 Gene3D G3DSA:1.10.10.60 28 67 2.3E-18 T 29-03-2018 SMALA_RS24025 d4230c0a0d2e3ea591b4b1b0d980229d 236 SUPERFAMILY SSF48498 113 223 5.56E-7 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS24025 d4230c0a0d2e3ea591b4b1b0d980229d 236 Gene3D G3DSA:1.10.357.10 97 225 3.7E-17 T 29-03-2018 SMALA_RS24025 d4230c0a0d2e3ea591b4b1b0d980229d 236 SUPERFAMILY SSF46689 31 111 1.28E-21 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS24025 d4230c0a0d2e3ea591b4b1b0d980229d 236 Gene3D G3DSA:1.10.260.40 68 96 6.6E-16 T 29-03-2018 SMALA_RS24025 d4230c0a0d2e3ea591b4b1b0d980229d 236 Pfam PF00440 Bacterial regulatory proteins, tetR family 46 90 4.8E-17 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS24025 d4230c0a0d2e3ea591b4b1b0d980229d 236 ProSitePatterns PS01081 TetR-type HTH domain signature. 58 88 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site SMALA_RS27395 1d95109378def23034820177e1229d48 243 SUPERFAMILY SSF52317 1 200 2.72E-40 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS27395 1d95109378def23034820177e1229d48 243 Pfam PF03575 Peptidase family S51 3 202 2.7E-58 T 29-03-2018 IPR005320 Peptidase S51 GO:0006508|GO:0008236 SMALA_RS27395 1d95109378def23034820177e1229d48 243 Gene3D G3DSA:3.40.50.880 1 228 4.7E-51 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS34745 37aefa08939e20d6fc3820e0a629aef9 78 Pfam PF04149 Domain of unknown function (DUF397) 10 62 4.1E-18 T 29-03-2018 IPR007278 Domain of unknown function DUF397 SMALA_RS38215 5bd65008790db19197186f9c2cc15092 276 Pfam PF01061 ABC-2 type transporter 25 239 1.4E-34 T 29-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 SMALA_RS38215 5bd65008790db19197186f9c2cc15092 276 PRINTS PR00164 ABC-2 type transport system membrane protein signature 44 65 5.1E-6 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMALA_RS38215 5bd65008790db19197186f9c2cc15092 276 PRINTS PR00164 ABC-2 type transport system membrane protein signature 218 237 5.1E-6 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMALA_RS38215 5bd65008790db19197186f9c2cc15092 276 PRINTS PR00164 ABC-2 type transport system membrane protein signature 198 217 5.1E-6 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMALA_RS38215 5bd65008790db19197186f9c2cc15092 276 PIRSF PIRSF006648 11 276 1.0E-57 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMALA_RS16700 cb493f4a719778af94058a8e531906ef 257 SUPERFAMILY SSF54292 24 127 4.39E-29 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SMALA_RS16700 cb493f4a719778af94058a8e531906ef 257 Gene3D G3DSA:1.10.1060.10 128 256 1.3E-27 T 29-03-2018 SMALA_RS16700 cb493f4a719778af94058a8e531906ef 257 Pfam PF13183 4Fe-4S dicluster domain 167 239 7.9E-12 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain SMALA_RS16700 cb493f4a719778af94058a8e531906ef 257 SUPERFAMILY SSF46548 128 253 1.03E-32 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 SMALA_RS16700 cb493f4a719778af94058a8e531906ef 257 Gene3D G3DSA:3.10.20.30 15 127 1.5E-35 T 29-03-2018 IPR012675 Beta-grasp domain SMALA_RS16700 cb493f4a719778af94058a8e531906ef 257 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 169 180 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site SMALA_RS16700 cb493f4a719778af94058a8e531906ef 257 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 30 249 1.2E-78 T 29-03-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMALA_RS16700 cb493f4a719778af94058a8e531906ef 257 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 27 132 2.2E-35 T 29-03-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMALA_RS21955 48ff588d496b8d726b0bcfd2504c691a 205 Gene3D G3DSA:3.40.30.10 55 203 8.3E-29 T 29-03-2018 SMALA_RS21955 48ff588d496b8d726b0bcfd2504c691a 205 SUPERFAMILY SSF52833 65 204 7.03E-31 T 29-03-2018 IPR012336 Thioredoxin-like fold SMALA_RS21955 48ff588d496b8d726b0bcfd2504c691a 205 Pfam PF00578 AhpC/TSA family 65 183 1.6E-20 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 SMALA_RS21955 48ff588d496b8d726b0bcfd2504c691a 205 ProSitePatterns PS00194 Thioredoxin family active site. 89 107 - T 29-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 SMALA_RS10510 f9d51a1f649f4c2991d13078f9b6f66b 465 Pfam PF00266 Aminotransferase class-V 47 437 1.3E-76 T 29-03-2018 IPR000192 Aminotransferase class V domain SMALA_RS10510 f9d51a1f649f4c2991d13078f9b6f66b 465 SUPERFAMILY SSF53383 44 446 4.76E-84 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS10510 f9d51a1f649f4c2991d13078f9b6f66b 465 Gene3D G3DSA:3.90.1150.10 302 444 1.6E-28 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS10510 f9d51a1f649f4c2991d13078f9b6f66b 465 Gene3D G3DSA:3.40.640.10 53 301 1.5E-46 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS36645 3b500aa4c1f7fb5a33ac7b38205f7e01 360 Gene3D G3DSA:3.50.50.60 193 289 4.8E-12 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS36645 3b500aa4c1f7fb5a33ac7b38205f7e01 360 Gene3D G3DSA:3.50.50.60 86 192 1.2E-18 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS36645 3b500aa4c1f7fb5a33ac7b38205f7e01 360 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 229 251 2.0E-13 T 29-03-2018 SMALA_RS36645 3b500aa4c1f7fb5a33ac7b38205f7e01 360 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 130 148 2.0E-13 T 29-03-2018 SMALA_RS36645 3b500aa4c1f7fb5a33ac7b38205f7e01 360 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 2.0E-13 T 29-03-2018 SMALA_RS36645 3b500aa4c1f7fb5a33ac7b38205f7e01 360 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 252 8.9E-34 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS36645 3b500aa4c1f7fb5a33ac7b38205f7e01 360 SUPERFAMILY SSF51905 1 288 2.52E-33 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS36645 3b500aa4c1f7fb5a33ac7b38205f7e01 360 Gene3D G3DSA:3.50.50.60 1 85 1.1E-13 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS36645 3b500aa4c1f7fb5a33ac7b38205f7e01 360 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 239 257 1.3E-6 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMALA_RS36645 3b500aa4c1f7fb5a33ac7b38205f7e01 360 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 5 27 1.3E-6 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMALA_RS36645 3b500aa4c1f7fb5a33ac7b38205f7e01 360 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 94 102 1.3E-6 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMALA_RS36645 3b500aa4c1f7fb5a33ac7b38205f7e01 360 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 126 150 1.3E-6 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMALA_RS34155 0be3da2568adaa08c3e6fc14d59da8d2 353 Pfam PF00877 NlpC/P60 family 217 308 4.8E-6 T 29-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain SMALA_RS34155 0be3da2568adaa08c3e6fc14d59da8d2 353 SUPERFAMILY SSF54001 193 324 6.87E-11 T 29-03-2018 SMALA_RS34155 0be3da2568adaa08c3e6fc14d59da8d2 353 Gene3D G3DSA:3.90.1720.10 136 347 3.0E-14 T 29-03-2018 SMALA_RS33955 e834fe3c0eda6711daea376d5a494940 429 SUPERFAMILY SSF53850 27 400 8.58E-41 T 29-03-2018 SMALA_RS33955 e834fe3c0eda6711daea376d5a494940 429 Gene3D G3DSA:3.40.190.10 240 399 0.4 T 29-03-2018 SMALA_RS33955 e834fe3c0eda6711daea376d5a494940 429 Gene3D G3DSA:3.40.190.10 41 226 4.1E-24 T 29-03-2018 SMALA_RS33955 e834fe3c0eda6711daea376d5a494940 429 Pfam PF01547 Bacterial extracellular solute-binding protein 55 346 2.1E-25 T 29-03-2018 IPR006059 Solute-binding family 1 GO:0006810 SMALA_RS13715 14fc07b196dea8ee074211e7f77bef7d 54 TIGRFAM TIGR04363 LD_lanti_pre: FxLD family lantipeptide 15 49 2.5E-13 T 29-03-2018 IPR027575 FxLD family lantipeptide SMALA_RS41800 d9ecd7ad738de5125a343cc31798c07f 207 Gene3D G3DSA:3.40.605.10 6 127 1.9E-21 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS41800 d9ecd7ad738de5125a343cc31798c07f 207 SUPERFAMILY SSF53720 40 113 1.3E-21 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMALA_RS41800 d9ecd7ad738de5125a343cc31798c07f 207 Pfam PF00171 Aldehyde dehydrogenase family 52 108 3.5E-20 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS28795 d12ac15dd24a11208617d3843a10dbe3 100 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 3 98 7.2E-13 T 29-03-2018 IPR008407 Branched-chain amino acid transport, AzlD SMALA_RS16365 06eb6831e125d4fbcaca72d650f69bbf 392 Gene3D G3DSA:3.40.50.1820 119 383 9.3E-27 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS16365 06eb6831e125d4fbcaca72d650f69bbf 392 SUPERFAMILY SSF53474 127 382 2.3E-27 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS16365 06eb6831e125d4fbcaca72d650f69bbf 392 Pfam PF00756 Putative esterase 144 376 4.3E-12 T 29-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 SMALA_RS06780 4c10adb077eaff72e91bfba6db37db8a 313 SUPERFAMILY SSF51735 1 296 2.6E-41 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS06780 4c10adb077eaff72e91bfba6db37db8a 313 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 226 1.2E-12 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 SMALA_RS06780 4c10adb077eaff72e91bfba6db37db8a 313 Gene3D G3DSA:3.40.50.720 1 181 9.8E-17 T 29-03-2018 SMALA_RS06780 4c10adb077eaff72e91bfba6db37db8a 313 Gene3D G3DSA:3.90.25.10 182 300 1.1E-13 T 29-03-2018 SMALA_RS37275 ea41e1b1c83c33f7ad5ec2408ffec17b 498 Gene3D G3DSA:3.30.420.40 15 244 1.4E-54 T 29-03-2018 SMALA_RS37275 ea41e1b1c83c33f7ad5ec2408ffec17b 498 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 256 442 3.2E-42 T 29-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 SMALA_RS37275 ea41e1b1c83c33f7ad5ec2408ffec17b 498 PIRSF PIRSF000538 17 495 1.6E-104 T 29-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 SMALA_RS37275 ea41e1b1c83c33f7ad5ec2408ffec17b 498 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 19 246 1.0E-42 T 29-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 SMALA_RS37275 ea41e1b1c83c33f7ad5ec2408ffec17b 498 SUPERFAMILY SSF53067 19 249 9.93E-57 T 29-03-2018 SMALA_RS37275 ea41e1b1c83c33f7ad5ec2408ffec17b 498 SUPERFAMILY SSF53067 250 489 6.04E-55 T 29-03-2018 SMALA_RS37275 ea41e1b1c83c33f7ad5ec2408ffec17b 498 Gene3D G3DSA:3.30.420.40 245 495 2.5E-51 T 29-03-2018 SMALA_RS31100 947716ff48db70180816751024ccd8ae 135 SUPERFAMILY SSF51182 5 129 7.54E-28 T 29-03-2018 IPR011051 RmlC-like cupin domain SMALA_RS31100 947716ff48db70180816751024ccd8ae 135 PIRSF PIRSF016602 1 135 9.1E-57 T 29-03-2018 IPR016672 Polyketide biosynthesis protein CurC, predicted SMALA_RS31100 947716ff48db70180816751024ccd8ae 135 Pfam PF07883 Cupin domain 42 108 1.1E-19 T 29-03-2018 IPR013096 Cupin 2, conserved barrel SMALA_RS31100 947716ff48db70180816751024ccd8ae 135 Gene3D G3DSA:2.60.120.10 10 131 4.6E-22 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SMALA_RS36485 118c65d832fddbbb3eb5025cf6f11ec9 489 Gene3D G3DSA:3.40.50.2300 65 231 0.037 T 29-03-2018 SMALA_RS36485 118c65d832fddbbb3eb5025cf6f11ec9 489 Pfam PF13458 Periplasmic binding protein 115 452 4.3E-10 T 29-03-2018 IPR028081 Leucine-binding protein domain SMALA_RS36485 118c65d832fddbbb3eb5025cf6f11ec9 489 Gene3D G3DSA:3.40.50.2300 232 421 3.7E-12 T 29-03-2018 SMALA_RS36485 118c65d832fddbbb3eb5025cf6f11ec9 489 SUPERFAMILY SSF53822 113 472 5.76E-21 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SMALA_RS05255 8df30a8e76f326afb7ab6df6b814c8b5 588 Gene3D G3DSA:2.160.20.10 298 546 1.9E-32 T 29-03-2018 IPR012334 Pectin lyase fold SMALA_RS05255 8df30a8e76f326afb7ab6df6b814c8b5 588 SUPERFAMILY SSF51126 413 498 2.9E-5 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor SMALA_RS05255 8df30a8e76f326afb7ab6df6b814c8b5 588 SUPERFAMILY SSF51126 303 365 2.9E-5 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor SMALA_RS39895 0d7a7d7f656a4de5cf3a4c76d5d65c2d 213 Gene3D G3DSA:3.40.30.10 57 172 1.7E-10 T 29-03-2018 SMALA_RS39895 0d7a7d7f656a4de5cf3a4c76d5d65c2d 213 Pfam PF01323 DSBA-like thioredoxin domain 6 55 6.0E-6 T 29-03-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 SMALA_RS39895 0d7a7d7f656a4de5cf3a4c76d5d65c2d 213 SUPERFAMILY SSF52833 5 171 8.14E-20 T 29-03-2018 IPR012336 Thioredoxin-like fold SMALA_RS39895 0d7a7d7f656a4de5cf3a4c76d5d65c2d 213 Gene3D G3DSA:3.40.30.10 3 56 2.6E-10 T 29-03-2018 SMALA_RS37010 62c8b94a9f7e4db0abc76f0eec8d230c 662 TIGRFAM TIGR02243 TIGR02243: putative baseplate assembly protein 7 626 1.8E-158 T 29-03-2018 IPR011749 Conserved hypothetical protein CHP02243 SMALA_RS37010 62c8b94a9f7e4db0abc76f0eec8d230c 662 Pfam PF04865 Baseplate J-like protein 398 586 2.4E-12 T 29-03-2018 IPR006949 Baseplate protein J-like SMALA_RS09350 124020279ac60f3a2ed36646823cb030 173 SUPERFAMILY SSF52540 9 165 3.12E-14 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS09350 124020279ac60f3a2ed36646823cb030 173 Gene3D G3DSA:3.40.50.300 7 168 3.7E-11 T 29-03-2018 SMALA_RS37505 8ac68b6592ffdcf7cae2f2c8ad0337ad 407 SUPERFAMILY SSF51261 288 400 5.23E-43 T 29-03-2018 IPR011055 Duplicated hybrid motif SMALA_RS37505 8ac68b6592ffdcf7cae2f2c8ad0337ad 407 Pfam PF01551 Peptidase family M23 299 396 1.1E-29 T 29-03-2018 IPR016047 Peptidase M23 SMALA_RS37505 8ac68b6592ffdcf7cae2f2c8ad0337ad 407 Gene3D G3DSA:3.10.350.10 156 261 7.6E-15 T 29-03-2018 SMALA_RS37505 8ac68b6592ffdcf7cae2f2c8ad0337ad 407 Pfam PF06737 Transglycosylase-like domain 42 117 6.6E-34 T 29-03-2018 IPR010618 Transglycosylase-like SMALA_RS37505 8ac68b6592ffdcf7cae2f2c8ad0337ad 407 Gene3D G3DSA:2.70.70.10 262 402 1.7E-39 T 29-03-2018 SMALA_RS37505 8ac68b6592ffdcf7cae2f2c8ad0337ad 407 SMART SM00257 176 225 1.0E-8 T 29-03-2018 IPR018392 LysM domain SMALA_RS37505 8ac68b6592ffdcf7cae2f2c8ad0337ad 407 Gene3D G3DSA:1.10.530.10 23 124 8.9E-31 T 29-03-2018 SMALA_RS37505 8ac68b6592ffdcf7cae2f2c8ad0337ad 407 SUPERFAMILY SSF54106 176 224 1.7E-5 T 29-03-2018 IPR018392 LysM domain SMALA_RS37505 8ac68b6592ffdcf7cae2f2c8ad0337ad 407 Pfam PF01476 LysM domain 177 224 3.2E-8 T 29-03-2018 IPR018392 LysM domain SMALA_RS37505 8ac68b6592ffdcf7cae2f2c8ad0337ad 407 SUPERFAMILY SSF53955 42 123 1.41E-31 T 29-03-2018 IPR023346 Lysozyme-like domain SMALA_RS21875 6dd323028e76f02e26e9a524aee87ffa 491 Pfam PF10935 Protein of unknown function (DUF2637) 16 171 2.2E-40 T 29-03-2018 IPR021235 Protein of unknown function DUF2637 SMALA_RS03940 d02e48d11e9828e86fbab290cf3eb520 244 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 12 129 3.8E-21 T 29-03-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 SMALA_RS03940 d02e48d11e9828e86fbab290cf3eb520 244 Gene3D G3DSA:1.20.120.450 1 135 1.8E-19 T 29-03-2018 SMALA_RS03940 d02e48d11e9828e86fbab290cf3eb520 244 Pfam PF07398 MDMPI C-terminal domain 143 235 1.4E-12 T 29-03-2018 IPR010872 MDMPI C-terminal SMALA_RS03940 d02e48d11e9828e86fbab290cf3eb520 244 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 10 220 2.9E-26 T 29-03-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type SMALA_RS03940 d02e48d11e9828e86fbab290cf3eb520 244 SUPERFAMILY SSF109854 5 132 6.64E-10 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes SMALA_RS01110 d7bcf02c9d3c7aa0806a14c60d48fbbd 439 Pfam PF13556 PucR C-terminal helix-turn-helix domain 375 432 2.6E-19 T 29-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain SMALA_RS01110 d7bcf02c9d3c7aa0806a14c60d48fbbd 439 Gene3D G3DSA:1.10.10.60 363 412 1.5E-6 T 29-03-2018 SMALA_RS01110 d7bcf02c9d3c7aa0806a14c60d48fbbd 439 Gene3D G3DSA:1.10.490.10 28 186 1.5E-7 T 29-03-2018 SMALA_RS12500 837198bef0062dacdf0d93036400d886 680 Gene3D G3DSA:1.10.10.10 540 620 0.15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS35355 d4033da923dc4ed7f3803d1dff713e7b 302 SUPERFAMILY SSF161098 64 267 1.44E-41 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS35355 d4033da923dc4ed7f3803d1dff713e7b 302 Gene3D G3DSA:1.10.3720.10 24 287 1.2E-47 T 29-03-2018 SMALA_RS35355 d4033da923dc4ed7f3803d1dff713e7b 302 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 64 127 4.7E-12 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 SMALA_RS35355 d4033da923dc4ed7f3803d1dff713e7b 302 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 281 1.6E-21 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS14895 89fb6b73e551f54aa81b838f7d9dc915 260 Gene3D G3DSA:3.40.50.1000 1 260 5.9E-30 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS14895 89fb6b73e551f54aa81b838f7d9dc915 260 Pfam PF13344 Haloacid dehalogenase-like hydrolase 10 109 1.2E-23 T 29-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA SMALA_RS14895 89fb6b73e551f54aa81b838f7d9dc915 260 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 11 231 3.0E-44 T 29-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA SMALA_RS14895 89fb6b73e551f54aa81b838f7d9dc915 260 SUPERFAMILY SSF56784 7 256 7.09E-64 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS14895 89fb6b73e551f54aa81b838f7d9dc915 260 Pfam PF13242 HAD-hyrolase-like 182 254 1.4E-20 T 29-03-2018 SMALA_RS14710 e98c9a406dd8b6137d45e2d5f9273182 108 Gene3D G3DSA:3.40.1260.10 1 103 7.1E-12 T 29-03-2018 SMALA_RS14710 e98c9a406dd8b6137d45e2d5f9273182 108 SUPERFAMILY SSF75169 3 103 1.62E-10 T 29-03-2018 IPR027396 DsrEFH-like SMALA_RS39640 6164bca63a35fe02155f281b0a7ef2f6 387 Pfam PF13378 Enolase C-terminal domain-like 153 373 6.4E-38 T 29-03-2018 IPR029065 Enolase C-terminal domain-like SMALA_RS39640 6164bca63a35fe02155f281b0a7ef2f6 387 SUPERFAMILY SSF51604 123 383 2.0E-49 T 29-03-2018 IPR029065 Enolase C-terminal domain-like SMALA_RS39640 6164bca63a35fe02155f281b0a7ef2f6 387 SUPERFAMILY SSF54826 21 123 2.83E-16 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMALA_RS39640 6164bca63a35fe02155f281b0a7ef2f6 387 Gene3D G3DSA:3.20.20.120 129 382 5.5E-38 T 29-03-2018 IPR029065 Enolase C-terminal domain-like SMALA_RS39640 6164bca63a35fe02155f281b0a7ef2f6 387 Gene3D G3DSA:3.30.390.10 1 128 5.0E-20 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMALA_RS39640 6164bca63a35fe02155f281b0a7ef2f6 387 SMART SM00922 147 248 2.2E-14 T 29-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal SMALA_RS39640 6164bca63a35fe02155f281b0a7ef2f6 387 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 33 123 1.2E-8 T 29-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain SMALA_RS12570 61b9f0491b6c4f99f1a812d1847dad3b 291 Gene3D G3DSA:1.10.3720.10 14 278 1.3E-38 T 29-03-2018 SMALA_RS12570 61b9f0491b6c4f99f1a812d1847dad3b 291 SUPERFAMILY SSF161098 22 288 5.7E-60 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS12570 61b9f0491b6c4f99f1a812d1847dad3b 291 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 284 1.8E-18 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS36055 1df253efc151236b033cea5f48a2ca18 439 Gene3D G3DSA:3.40.50.720 169 420 7.8E-30 T 29-03-2018 SMALA_RS36055 1df253efc151236b033cea5f48a2ca18 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 162 180 4.3E-10 T 29-03-2018 SMALA_RS36055 1df253efc151236b033cea5f48a2ca18 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 4.3E-10 T 29-03-2018 SMALA_RS36055 1df253efc151236b033cea5f48a2ca18 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 102 120 4.3E-10 T 29-03-2018 SMALA_RS36055 1df253efc151236b033cea5f48a2ca18 439 Gene3D G3DSA:3.40.50.720 146 168 0.066 T 29-03-2018 SMALA_RS36055 1df253efc151236b033cea5f48a2ca18 439 SUPERFAMILY SSF51905 222 348 4.64E-32 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS36055 1df253efc151236b033cea5f48a2ca18 439 SUPERFAMILY SSF51905 5 132 4.64E-32 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS36055 1df253efc151236b033cea5f48a2ca18 439 SUPERFAMILY SSF51905 161 179 4.64E-32 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS36055 1df253efc151236b033cea5f48a2ca18 439 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 328 3.2E-60 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS36055 1df253efc151236b033cea5f48a2ca18 439 Gene3D G3DSA:3.50.50.60 4 145 2.2E-16 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS32780 c9b376a3c6a8fdac5cc739bece0b3d8d 275 ProSitePatterns PS00770 Aminotransferases class-IV signature. 176 205 - T 29-03-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 SMALA_RS32780 c9b376a3c6a8fdac5cc739bece0b3d8d 275 Gene3D G3DSA:3.30.470.10 2 126 4.9E-31 T 29-03-2018 SMALA_RS32780 c9b376a3c6a8fdac5cc739bece0b3d8d 275 Pfam PF01063 Amino-transferase class IV 31 244 3.5E-49 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 SMALA_RS32780 c9b376a3c6a8fdac5cc739bece0b3d8d 275 SUPERFAMILY SSF56752 4 268 2.62E-69 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 SMALA_RS32780 c9b376a3c6a8fdac5cc739bece0b3d8d 275 Gene3D G3DSA:3.20.10.10 127 271 1.3E-42 T 29-03-2018 SMALA_RS00635 459ca5b18b5505b79508744b76114500 128 SUPERFAMILY SSF57716 91 123 9.27E-5 T 29-03-2018 SMALA_RS00635 459ca5b18b5505b79508744b76114500 128 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 89 123 5.9E-7 T 29-03-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 SMALA_RS20775 6a841f6f4b018a3440fd162aad61baaa 313 Gene3D G3DSA:3.40.50.1820 4 307 1.0E-36 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS20775 6a841f6f4b018a3440fd162aad61baaa 313 SUPERFAMILY SSF53474 13 302 2.04E-36 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS03395 c32d57fb5e7e1c09d02a97619f0719c8 148 SUPERFAMILY SSF51261 3 146 3.49E-35 T 29-03-2018 IPR011055 Duplicated hybrid motif SMALA_RS03395 c32d57fb5e7e1c09d02a97619f0719c8 148 Gene3D G3DSA:2.70.70.10 1 148 1.0E-47 T 29-03-2018 SMALA_RS03395 c32d57fb5e7e1c09d02a97619f0719c8 148 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 3 124 4.1E-37 T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 SMALA_RS23865 e1db2b83ec706a0e90e77a8819520b08 254 Pfam PF02361 Cobalt transport protein 14 218 8.2E-32 T 29-03-2018 IPR003339 ABC/ECF transporter, transmembrane component SMALA_RS23865 e1db2b83ec706a0e90e77a8819520b08 254 TIGRFAM TIGR02454 ECF_T_CbiQ: cobalt ECF transporter T component CbiQ 21 214 4.7E-48 T 29-03-2018 IPR012809 Cobalt ECF transporter T component CbiQ GO:0005887|GO:0006824|GO:0043190 SMALA_RS09655 04f2bf7e6171b278512dd58542553770 192 Gene3D G3DSA:2.60.60.30 19 185 8.3E-45 T 29-03-2018 SMALA_RS09655 04f2bf7e6171b278512dd58542553770 192 Pfam PF02342 TerD domain 2 183 4.7E-45 T 29-03-2018 IPR003325 TerD domain GO:0006950 SMALA_RS06065 f74fc52a335b065e2bf22acf154c40cf 404 PIRSF PIRSF016578 5 403 3.0E-115 T 29-03-2018 SMALA_RS06065 f74fc52a335b065e2bf22acf154c40cf 404 Gene3D G3DSA:1.10.540.10 3 122 5.2E-13 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS06065 f74fc52a335b065e2bf22acf154c40cf 404 SUPERFAMILY SSF47203 242 395 1.31E-11 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMALA_RS06065 f74fc52a335b065e2bf22acf154c40cf 404 Gene3D G3DSA:2.40.110.10 124 208 7.3E-16 T 29-03-2018 SMALA_RS06065 f74fc52a335b065e2bf22acf154c40cf 404 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 249 382 4.0E-23 T 29-03-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain SMALA_RS06065 f74fc52a335b065e2bf22acf154c40cf 404 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 32 99 1.0E-7 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS06065 f74fc52a335b065e2bf22acf154c40cf 404 SUPERFAMILY SSF56645 10 216 2.09E-33 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMALA_RS06065 f74fc52a335b065e2bf22acf154c40cf 404 Gene3D G3DSA:1.20.140.10 209 400 5.6E-13 T 29-03-2018 SMALA_RS06345 662c5dc17f4bc5968606838d16222444 166 SUPERFAMILY SSF109854 12 161 6.59E-36 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes SMALA_RS06345 662c5dc17f4bc5968606838d16222444 166 Pfam PF04978 Protein of unknown function (DUF664) 26 162 7.7E-38 T 29-03-2018 IPR007061 Protein of unknown function DUF664 SMALA_RS06345 662c5dc17f4bc5968606838d16222444 166 Gene3D G3DSA:1.20.120.450 2 166 4.0E-30 T 29-03-2018 SMALA_RS17310 07065cf2e074b00e3e9a49a0c45a6b9f 464 Gene3D G3DSA:1.20.1250.20 37 234 1.2E-20 T 29-03-2018 SMALA_RS17310 07065cf2e074b00e3e9a49a0c45a6b9f 464 Pfam PF05977 Transmembrane secretion effector 38 422 9.5E-51 T 29-03-2018 IPR010290 Transmembrane secretion effector SMALA_RS17310 07065cf2e074b00e3e9a49a0c45a6b9f 464 Gene3D G3DSA:1.20.1250.20 239 429 6.9E-19 T 29-03-2018 SMALA_RS17310 07065cf2e074b00e3e9a49a0c45a6b9f 464 SUPERFAMILY SSF103473 45 430 3.79E-47 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS30710 d710ad6646eb0cca4dd4402eda9d7a28 217 Gene3D G3DSA:1.10.10.60 2 58 1.5E-18 T 29-03-2018 SMALA_RS30710 d710ad6646eb0cca4dd4402eda9d7a28 217 Gene3D G3DSA:1.10.357.10 59 202 2.0E-23 T 29-03-2018 SMALA_RS30710 d710ad6646eb0cca4dd4402eda9d7a28 217 SUPERFAMILY SSF46689 7 77 4.19E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS30710 d710ad6646eb0cca4dd4402eda9d7a28 217 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 5.0E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS30710 d710ad6646eb0cca4dd4402eda9d7a28 217 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 5.0E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS30710 d710ad6646eb0cca4dd4402eda9d7a28 217 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 60 5.3E-15 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS04060 c3e08747c41906f58ad6cb02a730a087 264 Gene3D G3DSA:3.40.50.620 3 264 1.1E-75 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS04060 c3e08747c41906f58ad6cb02a730a087 264 PIRSF PIRSF000090 3 264 1.5E-82 T 29-03-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 SMALA_RS04060 c3e08747c41906f58ad6cb02a730a087 264 SUPERFAMILY SSF52402 3 258 9.52E-70 T 29-03-2018 SMALA_RS04060 c3e08747c41906f58ad6cb02a730a087 264 SMART SM00893 24 217 1.7E-58 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 SMALA_RS04060 c3e08747c41906f58ad6cb02a730a087 264 Pfam PF01012 Electron transfer flavoprotein domain 25 212 9.9E-47 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 SMALA_RS41945 b8b032e219e0723b4e9b62695f04bfb6 654 Pfam PF00326 Prolyl oligopeptidase family 448 649 4.9E-49 T 29-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 SMALA_RS41945 b8b032e219e0723b4e9b62695f04bfb6 654 Gene3D G3DSA:3.40.50.1820 379 654 4.7E-51 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS41945 b8b032e219e0723b4e9b62695f04bfb6 654 Pfam PF07676 WD40-like Beta Propeller Repeat 76 98 0.08 T 29-03-2018 IPR011659 WD40-like Beta Propeller SMALA_RS41945 b8b032e219e0723b4e9b62695f04bfb6 654 SUPERFAMILY SSF53474 397 648 8.04E-62 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS41945 b8b032e219e0723b4e9b62695f04bfb6 654 SUPERFAMILY SSF82171 32 374 2.75E-25 T 29-03-2018 SMALA_RS41945 b8b032e219e0723b4e9b62695f04bfb6 654 Gene3D G3DSA:2.140.10.30 75 378 3.2E-21 T 29-03-2018 SMALA_RS38190 ada9f7e8a596da8048a0f2945f3a6bac 355 SUPERFAMILY SSF53686 34 303 1.57E-46 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMALA_RS38190 ada9f7e8a596da8048a0f2945f3a6bac 355 Gene3D G3DSA:3.40.50.1100 33 132 4.7E-14 T 29-03-2018 SMALA_RS38190 ada9f7e8a596da8048a0f2945f3a6bac 355 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 34 265 9.6E-26 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMALA_RS38190 ada9f7e8a596da8048a0f2945f3a6bac 355 Gene3D G3DSA:3.40.50.1100 133 304 4.6E-27 T 29-03-2018 SMALA_RS11490 86bb93c5edef4b163b05ea73ce45890d 427 Pfam PF14378 PAP2 superfamily 158 341 3.5E-18 T 29-03-2018 IPR026841 Inositolphosphotransferase Aur1/Ipt1 SMALA_RS00765 202cc3fc8a94263716a187363f178f49 316 Gene3D G3DSA:3.30.565.10 190 315 2.1E-4 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS00765 202cc3fc8a94263716a187363f178f49 316 Pfam PF14417 MEDS: MEthanogen/methylotroph, DcmR Sensory domain 17 159 8.8E-27 T 29-03-2018 IPR025847 MEDS domain SMALA_RS00765 202cc3fc8a94263716a187363f178f49 316 Pfam PF13581 Histidine kinase-like ATPase domain 204 313 3.5E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS27100 4256eb497cdd35038ee3fb64b59ebcae 97 Gene3D G3DSA:3.30.70.930 1 96 5.5E-34 T 29-03-2018 IPR029756 MTH1187/YkoF-like SMALA_RS27100 4256eb497cdd35038ee3fb64b59ebcae 97 TIGRFAM TIGR00106 TIGR00106: uncharacterized protein, MTH1187 family 1 94 2.6E-19 T 29-03-2018 IPR002767 Thiamine-binding protein SMALA_RS27100 4256eb497cdd35038ee3fb64b59ebcae 97 SUPERFAMILY SSF89957 1 95 8.77E-30 T 29-03-2018 IPR029756 MTH1187/YkoF-like SMALA_RS27100 4256eb497cdd35038ee3fb64b59ebcae 97 Pfam PF01910 Thiamine-binding protein 3 92 3.7E-30 T 29-03-2018 IPR002767 Thiamine-binding protein SMALA_RS20085 595b2a98e8eb611658160d61dbb7707a 232 Pfam PF14016 Protein of unknown function (DUF4232) 101 223 1.1E-21 T 29-03-2018 IPR025326 Protein of unknown function DUF4232 SMALA_RS35220 9730e77198fceeb81ba6957eabe90bc8 452 Gene3D G3DSA:3.20.140.10 1 364 1.6E-98 T 29-03-2018 SMALA_RS35220 9730e77198fceeb81ba6957eabe90bc8 452 SUPERFAMILY SSF51690 133 431 8.68E-89 T 29-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 SMALA_RS35220 9730e77198fceeb81ba6957eabe90bc8 452 SUPERFAMILY SSF54675 3 131 4.37E-30 T 29-03-2018 SMALA_RS35220 9730e77198fceeb81ba6957eabe90bc8 452 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 150 338 5.9E-7 T 29-03-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 SMALA_RS35220 9730e77198fceeb81ba6957eabe90bc8 452 PIRSF PIRSF000484 1 431 6.0E-114 T 29-03-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 SMALA_RS35220 9730e77198fceeb81ba6957eabe90bc8 452 TIGRFAM TIGR01513 NAPRTase_put: nicotinate phosphoribosyltransferase 4 415 5.0E-127 T 29-03-2018 IPR006405 Nicotinate phosphoribosyltransferase pncB-type GO:0004516|GO:0019358 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264|Reactome: R-HSA-6798695 SMALA_RS15860 442f0d5de2b2488dd7f05c64fb2f4d15 139 SUPERFAMILY SSF55486 16 136 3.66E-23 T 29-03-2018 SMALA_RS15860 442f0d5de2b2488dd7f05c64fb2f4d15 139 Pfam PF06262 Zincin-like metallopeptidase 74 134 1.8E-9 T 29-03-2018 IPR010428 Zincin-like metallopeptidase SMALA_RS33390 a0812d73a473a703816ddc824fc33593 201 Gene3D G3DSA:3.20.19.10 1 168 1.2E-46 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel SMALA_RS33390 a0812d73a473a703816ddc824fc33593 201 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 191 35.889 T 29-03-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 SMALA_RS33390 a0812d73a473a703816ddc824fc33593 201 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 180 5.9E-53 T 29-03-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 SMALA_RS33390 a0812d73a473a703816ddc824fc33593 201 SUPERFAMILY SSF52016 1 189 3.53E-49 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel SMALA_RS33390 a0812d73a473a703816ddc824fc33593 201 Pfam PF00694 Aconitase C-terminal domain 2 117 4.2E-23 T 29-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS05420 8e428636c401d0b6c0e9af1ef25ac73d 204 Gene3D G3DSA:3.40.50.1240 1 203 4.6E-55 T 29-03-2018 IPR029033 Histidine phosphatase superfamily SMALA_RS05420 8e428636c401d0b6c0e9af1ef25ac73d 204 SUPERFAMILY SSF53254 3 199 3.19E-57 T 29-03-2018 IPR029033 Histidine phosphatase superfamily SMALA_RS05420 8e428636c401d0b6c0e9af1ef25ac73d 204 SMART SM00855 3 157 4.0E-21 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SMALA_RS05420 8e428636c401d0b6c0e9af1ef25ac73d 204 PIRSF PIRSF000709 3 174 2.4E-13 T 29-03-2018 SMALA_RS05420 8e428636c401d0b6c0e9af1ef25ac73d 204 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 197 5.6E-57 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SMALA_RS36370 8dbc4e448d9d248c1b174aa1a27b43aa 236 Pfam PF03729 Short repeat of unknown function (DUF308) 107 177 5.2E-9 T 29-03-2018 IPR005325 Protein of unknown function DUF308, membrane SMALA_RS36370 8dbc4e448d9d248c1b174aa1a27b43aa 236 Pfam PF03729 Short repeat of unknown function (DUF308) 164 214 6.0E-8 T 29-03-2018 IPR005325 Protein of unknown function DUF308, membrane SMALA_RS36370 8dbc4e448d9d248c1b174aa1a27b43aa 236 Pfam PF03729 Short repeat of unknown function (DUF308) 51 120 8.8E-14 T 29-03-2018 IPR005325 Protein of unknown function DUF308, membrane SMALA_RS06335 c451947349cb7ee2aa35576e72745459 198 Pfam PF13560 Helix-turn-helix domain 13 71 1.1E-16 T 29-03-2018 SMALA_RS06335 c451947349cb7ee2aa35576e72745459 198 Pfam PF07883 Cupin domain 120 177 7.5E-10 T 29-03-2018 IPR013096 Cupin 2, conserved barrel SMALA_RS06335 c451947349cb7ee2aa35576e72745459 198 SUPERFAMILY SSF51182 67 177 2.51E-20 T 29-03-2018 IPR011051 RmlC-like cupin domain SMALA_RS06335 c451947349cb7ee2aa35576e72745459 198 SUPERFAMILY SSF47413 4 76 1.24E-19 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS06335 c451947349cb7ee2aa35576e72745459 198 Gene3D G3DSA:2.60.120.10 70 196 1.9E-16 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SMALA_RS06335 c451947349cb7ee2aa35576e72745459 198 SMART SM00530 16 71 9.5E-19 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS06335 c451947349cb7ee2aa35576e72745459 198 Gene3D G3DSA:1.10.260.40 3 69 1.6E-21 T 29-03-2018 SMALA_RS02390 5174831883e754946d4eee00484a82c7 551 Gene3D G3DSA:2.120.10.30 443 551 3.9E-8 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like SMALA_RS02390 5174831883e754946d4eee00484a82c7 551 Gene3D G3DSA:2.120.10.30 4 134 6.5E-12 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like SMALA_RS02390 5174831883e754946d4eee00484a82c7 551 Gene3D G3DSA:2.120.10.30 324 442 1.7E-11 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like SMALA_RS02390 5174831883e754946d4eee00484a82c7 551 SUPERFAMILY SSF63829 344 548 6.7E-25 T 29-03-2018 SMALA_RS02390 5174831883e754946d4eee00484a82c7 551 Gene3D G3DSA:2.120.10.30 137 317 4.7E-16 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like SMALA_RS02390 5174831883e754946d4eee00484a82c7 551 SUPERFAMILY SSF63829 29 199 7.19E-26 T 29-03-2018 SMALA_RS02390 5174831883e754946d4eee00484a82c7 551 SUPERFAMILY SSF63829 239 299 7.19E-26 T 29-03-2018 SMALA_RS00115 267191829d8d7ee7c6c9807533505ac1 166 Pfam PF13396 Phospholipase_D-nuclease N-terminal 12 57 2.4E-12 T 29-03-2018 IPR027379 Cardiolipin synthase N-terminal SMALA_RS21975 267191829d8d7ee7c6c9807533505ac1 166 Pfam PF13396 Phospholipase_D-nuclease N-terminal 12 57 2.4E-12 T 29-03-2018 IPR027379 Cardiolipin synthase N-terminal SMALA_RS38625 e48f88929eabe003253815d7b96e85a1 711 Gene3D G3DSA:2.70.98.60 2 290 5.6E-82 T 29-03-2018 SMALA_RS38625 e48f88929eabe003253815d7b96e85a1 711 Pfam PF16874 Glycosyl hydrolase family 36 C-terminal domain 627 703 1.9E-10 T 29-03-2018 IPR031705 Glycosyl hydrolase family 36, C-terminal KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 SMALA_RS38625 e48f88929eabe003253815d7b96e85a1 711 Pfam PF02065 Melibiase 271 613 6.1E-118 T 29-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 SMALA_RS38625 e48f88929eabe003253815d7b96e85a1 711 Pfam PF16875 Glycosyl hydrolase family 36 N-terminal domain 30 265 3.6E-55 T 29-03-2018 IPR031704 Glycosyl hydrolase family 36, N-terminal KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 SMALA_RS38625 e48f88929eabe003253815d7b96e85a1 711 PRINTS PR00743 Glycosyl hydrolase family 36 signature 222 237 5.5E-50 T 29-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 SMALA_RS38625 e48f88929eabe003253815d7b96e85a1 711 PRINTS PR00743 Glycosyl hydrolase family 36 signature 445 460 5.5E-50 T 29-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 SMALA_RS38625 e48f88929eabe003253815d7b96e85a1 711 PRINTS PR00743 Glycosyl hydrolase family 36 signature 273 293 5.5E-50 T 29-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 SMALA_RS38625 e48f88929eabe003253815d7b96e85a1 711 PRINTS PR00743 Glycosyl hydrolase family 36 signature 387 409 5.5E-50 T 29-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 SMALA_RS38625 e48f88929eabe003253815d7b96e85a1 711 PRINTS PR00743 Glycosyl hydrolase family 36 signature 498 514 5.5E-50 T 29-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 SMALA_RS38625 e48f88929eabe003253815d7b96e85a1 711 PRINTS PR00743 Glycosyl hydrolase family 36 signature 523 539 5.5E-50 T 29-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 SMALA_RS38625 e48f88929eabe003253815d7b96e85a1 711 PRINTS PR00743 Glycosyl hydrolase family 36 signature 309 323 5.5E-50 T 29-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 SMALA_RS38625 e48f88929eabe003253815d7b96e85a1 711 PRINTS PR00743 Glycosyl hydrolase family 36 signature 337 352 5.5E-50 T 29-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 SMALA_RS38625 e48f88929eabe003253815d7b96e85a1 711 Gene3D G3DSA:2.60.40.1180 611 707 8.1E-16 T 29-03-2018 SMALA_RS38625 e48f88929eabe003253815d7b96e85a1 711 Gene3D G3DSA:3.20.20.70 293 610 2.5E-55 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS38625 e48f88929eabe003253815d7b96e85a1 711 SUPERFAMILY SSF51445 307 643 4.21E-95 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS38625 e48f88929eabe003253815d7b96e85a1 711 PIRSF PIRSF005536 3 701 2.2E-184 T 29-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 SMALA_RS03160 34e762d2d67cee740d972a6f582442e1 296 Gene3D G3DSA:3.40.50.1820 19 274 6.0E-42 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS03160 34e762d2d67cee740d972a6f582442e1 296 SUPERFAMILY SSF53474 17 276 1.76E-42 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS03160 34e762d2d67cee740d972a6f582442e1 296 Pfam PF12697 Alpha/beta hydrolase family 43 264 6.4E-18 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS13480 36ecf4cbc40fd1a2077a2cb4b2b0fc53 456 SUPERFAMILY SSF53300 67 243 1.63E-21 T 29-03-2018 IPR002035 von Willebrand factor, type A SMALA_RS13480 36ecf4cbc40fd1a2077a2cb4b2b0fc53 456 SMART SM00327 66 243 4.2E-10 T 29-03-2018 IPR002035 von Willebrand factor, type A SMALA_RS13480 36ecf4cbc40fd1a2077a2cb4b2b0fc53 456 Pfam PF13519 von Willebrand factor type A domain 69 178 5.6E-10 T 29-03-2018 IPR002035 von Willebrand factor, type A SMALA_RS13480 36ecf4cbc40fd1a2077a2cb4b2b0fc53 456 Gene3D G3DSA:3.40.50.410 65 248 5.4E-24 T 29-03-2018 IPR002035 von Willebrand factor, type A SMALA_RS14950 b8d60c4a6c89ca89db198be03f0c14b5 435 Gene3D G3DSA:3.40.50.1110 217 423 4.1E-29 T 29-03-2018 SMALA_RS14950 b8d60c4a6c89ca89db198be03f0c14b5 435 SUPERFAMILY SSF52266 216 422 4.12E-45 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain SMALA_RS14950 b8d60c4a6c89ca89db198be03f0c14b5 435 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 226 417 1.2E-23 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain SMALA_RS21155 8aac5c5da0ebfd300f138bdb9b66352c 316 Gene3D G3DSA:3.40.50.150 1 202 3.8E-44 T 29-03-2018 SMALA_RS21155 8aac5c5da0ebfd300f138bdb9b66352c 316 SUPERFAMILY SSF53335 256 303 2.49E-59 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS21155 8aac5c5da0ebfd300f138bdb9b66352c 316 SUPERFAMILY SSF53335 2 227 2.49E-59 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS21155 8aac5c5da0ebfd300f138bdb9b66352c 316 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 147 160 3.4E-5 T 29-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 SMALA_RS21155 8aac5c5da0ebfd300f138bdb9b66352c 316 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 100 114 3.4E-5 T 29-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 SMALA_RS21155 8aac5c5da0ebfd300f138bdb9b66352c 316 Pfam PF00145 C-5 cytosine-specific DNA methylase 257 304 2.3E-8 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS21155 8aac5c5da0ebfd300f138bdb9b66352c 316 Pfam PF00145 C-5 cytosine-specific DNA methylase 2 187 1.5E-32 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS21155 8aac5c5da0ebfd300f138bdb9b66352c 316 TIGRFAM TIGR00675 dcm: DNA (cytosine-5-)-methyltransferase 2 189 3.0E-31 T 29-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 SMALA_RS21155 8aac5c5da0ebfd300f138bdb9b66352c 316 Gene3D G3DSA:3.90.120.10 254 290 2.7E-6 T 29-03-2018 SMALA_RS30365 f0d460e4b938b8f6daa76318fa40da24 479 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 364 470 1.6E-21 T 29-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 SMALA_RS30365 f0d460e4b938b8f6daa76318fa40da24 479 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 426 441 2.0E-38 T 29-03-2018 SMALA_RS30365 f0d460e4b938b8f6daa76318fa40da24 479 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 266 280 2.0E-38 T 29-03-2018 SMALA_RS30365 f0d460e4b938b8f6daa76318fa40da24 479 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 310 317 2.0E-38 T 29-03-2018 SMALA_RS30365 f0d460e4b938b8f6daa76318fa40da24 479 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 142 151 2.0E-38 T 29-03-2018 SMALA_RS30365 f0d460e4b938b8f6daa76318fa40da24 479 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 178 203 2.0E-38 T 29-03-2018 SMALA_RS30365 f0d460e4b938b8f6daa76318fa40da24 479 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 31 46 2.0E-38 T 29-03-2018 SMALA_RS30365 f0d460e4b938b8f6daa76318fa40da24 479 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 360 381 2.0E-38 T 29-03-2018 SMALA_RS30365 f0d460e4b938b8f6daa76318fa40da24 479 Gene3D G3DSA:3.30.390.30 350 479 2.3E-28 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SMALA_RS30365 f0d460e4b938b8f6daa76318fa40da24 479 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 139 157 5.3E-9 T 29-03-2018 SMALA_RS30365 f0d460e4b938b8f6daa76318fa40da24 479 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 178 196 5.3E-9 T 29-03-2018 SMALA_RS30365 f0d460e4b938b8f6daa76318fa40da24 479 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 265 281 5.3E-9 T 29-03-2018 SMALA_RS30365 f0d460e4b938b8f6daa76318fa40da24 479 Gene3D G3DSA:3.40.50.720 169 341 6.0E-30 T 29-03-2018 SMALA_RS30365 f0d460e4b938b8f6daa76318fa40da24 479 PIRSF PIRSF000350 1 475 3.4E-61 T 29-03-2018 SMALA_RS30365 f0d460e4b938b8f6daa76318fa40da24 479 SUPERFAMILY SSF51905 1 339 6.14E-36 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS30365 f0d460e4b938b8f6daa76318fa40da24 479 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 1 323 6.3E-43 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS30365 f0d460e4b938b8f6daa76318fa40da24 479 SUPERFAMILY SSF55424 360 477 1.89E-27 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SMALA_RS30365 f0d460e4b938b8f6daa76318fa40da24 479 Gene3D G3DSA:3.50.50.60 1 168 1.5E-11 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS16510 8e53e3afca6e2bf6ac5b15bbe7ca6502 375 Pfam PF02653 Branched-chain amino acid transport system / permease component 57 336 4.2E-44 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 SMALA_RS16510 8e53e3afca6e2bf6ac5b15bbe7ca6502 375 Gene3D G3DSA:1.10.3470.10 4 347 9.5E-41 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SMALA_RS22020 10176758dfc24749bd72d286ba8ac46c 442 Pfam PF00375 Sodium:dicarboxylate symporter family 22 409 1.2E-110 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SMALA_RS22020 10176758dfc24749bd72d286ba8ac46c 442 Gene3D G3DSA:1.10.3860.10 15 418 3.4E-110 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SMALA_RS22020 10176758dfc24749bd72d286ba8ac46c 442 SUPERFAMILY SSF118215 22 410 4.18E-101 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SMALA_RS22020 10176758dfc24749bd72d286ba8ac46c 442 PRINTS PR00173 Glutamate-aspartate symporter signature 92 117 3.6E-27 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SMALA_RS22020 10176758dfc24749bd72d286ba8ac46c 442 PRINTS PR00173 Glutamate-aspartate symporter signature 202 221 3.6E-27 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SMALA_RS22020 10176758dfc24749bd72d286ba8ac46c 442 PRINTS PR00173 Glutamate-aspartate symporter signature 20 40 3.6E-27 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SMALA_RS22020 10176758dfc24749bd72d286ba8ac46c 442 PRINTS PR00173 Glutamate-aspartate symporter signature 304 330 3.6E-27 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SMALA_RS22020 10176758dfc24749bd72d286ba8ac46c 442 PRINTS PR00173 Glutamate-aspartate symporter signature 339 358 3.6E-27 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SMALA_RS22020 10176758dfc24749bd72d286ba8ac46c 442 PRINTS PR00173 Glutamate-aspartate symporter signature 365 385 3.6E-27 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SMALA_RS22020 10176758dfc24749bd72d286ba8ac46c 442 PRINTS PR00173 Glutamate-aspartate symporter signature 62 82 3.6E-27 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SMALA_RS22625 6fd52ee51480d498f42f334d58810b1d 201 Gene3D G3DSA:3.30.160.20 33 94 4.0E-25 T 29-03-2018 SMALA_RS22625 6fd52ee51480d498f42f334d58810b1d 201 SUPERFAMILY SSF54768 33 99 1.46E-21 T 29-03-2018 SMALA_RS22625 6fd52ee51480d498f42f334d58810b1d 201 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 32 186 8.9E-68 T 29-03-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 SMALA_RS22625 6fd52ee51480d498f42f334d58810b1d 201 SUPERFAMILY SSF54211 102 181 2.53E-25 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SMALA_RS22625 6fd52ee51480d498f42f334d58810b1d 201 Pfam PF03719 Ribosomal protein S5, C-terminal domain 110 180 1.1E-29 T 29-03-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 SMALA_RS22625 6fd52ee51480d498f42f334d58810b1d 201 Gene3D G3DSA:3.30.230.10 100 189 3.4E-30 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SMALA_RS22625 6fd52ee51480d498f42f334d58810b1d 201 Pfam PF00333 Ribosomal protein S5, N-terminal domain 36 98 5.3E-27 T 29-03-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 SMALA_RS22625 6fd52ee51480d498f42f334d58810b1d 201 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 4 186 34.797 T 29-03-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 SMALA_RS22625 6fd52ee51480d498f42f334d58810b1d 201 ProSitePatterns PS00585 Ribosomal protein S5 signature. 51 83 - T 29-03-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site SMALA_RS24685 93816cc4d04d322921b4a4a492288cb4 517 Pfam PF01594 AI-2E family transporter 151 472 8.8E-60 T 29-03-2018 IPR002549 Transmembrane protein TqsA-like SMALA_RS08440 651dca8b231a3f6a8d9f8d3deb699961 290 SUPERFAMILY SSF46689 239 274 2.91E-5 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS08440 651dca8b231a3f6a8d9f8d3deb699961 290 Pfam PF12833 Helix-turn-helix domain 191 274 5.1E-17 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS08440 651dca8b231a3f6a8d9f8d3deb699961 290 Gene3D G3DSA:1.10.10.60 222 282 1.3E-11 T 29-03-2018 SMALA_RS08440 651dca8b231a3f6a8d9f8d3deb699961 290 SMART SM00342 185 273 2.2E-12 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS08440 651dca8b231a3f6a8d9f8d3deb699961 290 Gene3D G3DSA:1.10.10.60 147 221 6.0E-7 T 29-03-2018 SMALA_RS35140 31cd614a26dab8a22fc8fd1c5ec1a0e8 258 SUPERFAMILY SSF51658 4 223 1.8E-25 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SMALA_RS35140 31cd614a26dab8a22fc8fd1c5ec1a0e8 258 Pfam PF01261 Xylose isomerase-like TIM barrel 21 190 7.2E-18 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SMALA_RS35140 31cd614a26dab8a22fc8fd1c5ec1a0e8 258 Gene3D G3DSA:3.20.20.150 1 257 4.3E-30 T 29-03-2018 SMALA_RS39230 58cb34506c38a5a772406f8172686f60 350 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 76 310 5.1E-54 T 29-03-2018 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 SMALA_RS39230 58cb34506c38a5a772406f8172686f60 350 SUPERFAMILY SSF51197 70 324 1.51E-79 T 29-03-2018 SMALA_RS39230 58cb34506c38a5a772406f8172686f60 350 Gene3D G3DSA:3.60.130.10 56 335 1.3E-68 T 29-03-2018 SMALA_RS01320 9084e5996f4a25e009f4dd8e89334351 386 SUPERFAMILY SSF56601 10 222 1.42E-74 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMALA_RS01320 9084e5996f4a25e009f4dd8e89334351 386 SUPERFAMILY SSF56601 252 370 1.42E-74 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMALA_RS01320 9084e5996f4a25e009f4dd8e89334351 386 Gene3D G3DSA:3.40.710.10 1 386 2.5E-83 T 29-03-2018 SMALA_RS01320 9084e5996f4a25e009f4dd8e89334351 386 Pfam PF00144 Beta-lactamase 22 379 5.8E-71 T 29-03-2018 IPR001466 Beta-lactamase-related SMALA_RS20830 ff9d2a5843a92662ec0dabb652346796 453 Gene3D G3DSA:3.90.1150.10 325 453 3.1E-24 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS20830 ff9d2a5843a92662ec0dabb652346796 453 SUPERFAMILY SSF53383 17 446 1.65E-120 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS20830 ff9d2a5843a92662ec0dabb652346796 453 Pfam PF00202 Aminotransferase class-III 36 445 4.5E-97 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMALA_RS20830 ff9d2a5843a92662ec0dabb652346796 453 Gene3D G3DSA:3.40.640.10 197 324 9.6E-45 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS20830 ff9d2a5843a92662ec0dabb652346796 453 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 250 287 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMALA_RS20830 ff9d2a5843a92662ec0dabb652346796 453 Gene3D G3DSA:3.90.1150.10 4 196 5.3E-45 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS00440 0ddb8066b91eeee7e4c9a3f68581f986 73 Pfam PF03621 MbtH-like protein 3 51 2.0E-21 T 29-03-2018 IPR005153 MbtH-like protein SMALA_RS00440 0ddb8066b91eeee7e4c9a3f68581f986 73 SUPERFAMILY SSF160582 4 67 5.49E-27 T 29-03-2018 SMALA_RS00440 0ddb8066b91eeee7e4c9a3f68581f986 73 SMART SM00923 2 52 1.2E-21 T 29-03-2018 IPR005153 MbtH-like protein SMALA_RS00440 0ddb8066b91eeee7e4c9a3f68581f986 73 Gene3D G3DSA:3.90.820.10 2 67 8.3E-32 T 29-03-2018 SMALA_RS01990 9d4e446c3c33a70bf86570e3a404720e 340 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 9 127 8.0E-27 T 29-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 SMALA_RS01990 9d4e446c3c33a70bf86570e3a404720e 340 Gene3D G3DSA:3.40.50.720 1 137 1.6E-43 T 29-03-2018 SMALA_RS01990 9d4e446c3c33a70bf86570e3a404720e 340 Gene3D G3DSA:3.30.360.10 138 336 3.4E-37 T 29-03-2018 SMALA_RS01990 9d4e446c3c33a70bf86570e3a404720e 340 SUPERFAMILY SSF51735 5 155 2.82E-48 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS01990 9d4e446c3c33a70bf86570e3a404720e 340 SUPERFAMILY SSF55347 135 303 6.54E-25 T 29-03-2018 SMALA_RS29150 8640330f934f357fa51a92917c21c9d4 278 Pfam PF00581 Rhodanese-like domain 159 265 2.2E-11 T 29-03-2018 IPR001763 Rhodanese-like domain SMALA_RS29150 8640330f934f357fa51a92917c21c9d4 278 Pfam PF00581 Rhodanese-like domain 8 126 3.0E-18 T 29-03-2018 IPR001763 Rhodanese-like domain SMALA_RS29150 8640330f934f357fa51a92917c21c9d4 278 ProSitePatterns PS00380 Rhodanese signature 1. 38 49 - T 29-03-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 SMALA_RS29150 8640330f934f357fa51a92917c21c9d4 278 Gene3D G3DSA:3.40.250.10 1 147 1.4E-32 T 29-03-2018 IPR001763 Rhodanese-like domain SMALA_RS29150 8640330f934f357fa51a92917c21c9d4 278 SMART SM00450 151 269 3.2E-17 T 29-03-2018 IPR001763 Rhodanese-like domain SMALA_RS29150 8640330f934f357fa51a92917c21c9d4 278 SMART SM00450 6 130 1.1E-24 T 29-03-2018 IPR001763 Rhodanese-like domain SMALA_RS29150 8640330f934f357fa51a92917c21c9d4 278 SUPERFAMILY SSF52821 4 147 3.01E-36 T 29-03-2018 IPR001763 Rhodanese-like domain SMALA_RS29150 8640330f934f357fa51a92917c21c9d4 278 Gene3D G3DSA:3.40.250.10 148 278 3.9E-25 T 29-03-2018 IPR001763 Rhodanese-like domain SMALA_RS29150 8640330f934f357fa51a92917c21c9d4 278 SUPERFAMILY SSF52821 149 275 8.77E-33 T 29-03-2018 IPR001763 Rhodanese-like domain SMALA_RS28595 4491b9e840296c4148df934d8a81f97f 770 SUPERFAMILY SSF140453 7 97 4.84E-6 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like SMALA_RS28595 4491b9e840296c4148df934d8a81f97f 770 Gene3D G3DSA:1.10.287.850 7 99 1.7E-9 T 29-03-2018 SMALA_RS09285 0ae7421d3ccbf1ef232754a829b0b8cd 219 Gene3D G3DSA:1.10.10.10 127 219 9.8E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS09285 0ae7421d3ccbf1ef232754a829b0b8cd 219 SMART SM00448 1 115 1.3E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS09285 0ae7421d3ccbf1ef232754a829b0b8cd 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 186 5.2E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS09285 0ae7421d3ccbf1ef232754a829b0b8cd 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 170 5.2E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS09285 0ae7421d3ccbf1ef232754a829b0b8cd 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 186 198 5.2E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS09285 0ae7421d3ccbf1ef232754a829b0b8cd 219 SUPERFAMILY SSF52172 1 180 3.92E-32 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS09285 0ae7421d3ccbf1ef232754a829b0b8cd 219 Pfam PF00072 Response regulator receiver domain 3 116 1.8E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS09285 0ae7421d3ccbf1ef232754a829b0b8cd 219 ProSitePatterns PS00622 LuxR-type HTH domain signature. 170 197 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS09285 0ae7421d3ccbf1ef232754a829b0b8cd 219 Gene3D G3DSA:3.40.50.2300 1 126 3.8E-33 T 29-03-2018 SMALA_RS09285 0ae7421d3ccbf1ef232754a829b0b8cd 219 SMART SM00421 153 210 3.3E-22 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS09285 0ae7421d3ccbf1ef232754a829b0b8cd 219 Pfam PF00196 Bacterial regulatory proteins, luxR family 155 209 9.1E-18 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS19870 ec19e803dc963b21a47d0b8cd188a313 280 Gene3D G3DSA:2.60.200.20 115 278 1.8E-22 T 29-03-2018 SMALA_RS19870 ec19e803dc963b21a47d0b8cd188a313 280 Pfam PF00498 FHA domain 208 269 7.4E-15 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 SMALA_RS19870 ec19e803dc963b21a47d0b8cd188a313 280 SUPERFAMILY SSF49879 146 276 9.76E-23 T 29-03-2018 IPR008984 SMAD/FHA domain GO:0005515 SMALA_RS19870 ec19e803dc963b21a47d0b8cd188a313 280 Pfam PF12401 Protein of unknown function (DUF2662) 4 118 8.5E-42 T 29-03-2018 IPR022128 Domain of unknown function DUF3662 SMALA_RS19870 ec19e803dc963b21a47d0b8cd188a313 280 SMART SM00240 206 255 8.6E-12 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 SMALA_RS28350 e3f524f00518c28ac0376f3b469a7ad0 292 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 86 277 3.3E-13 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS28350 e3f524f00518c28ac0376f3b469a7ad0 292 Gene3D G3DSA:1.10.3720.10 11 285 7.1E-44 T 29-03-2018 SMALA_RS28350 e3f524f00518c28ac0376f3b469a7ad0 292 SUPERFAMILY SSF161098 7 285 7.46E-52 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS09480 befa7c622a5f22d0514296ecf5d6315e 473 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 17 464 1.1E-221 T 29-03-2018 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 SMALA_RS09480 befa7c622a5f22d0514296ecf5d6315e 473 Pfam PF01458 Uncharacterized protein family (UPF0051) 219 444 7.0E-76 T 29-03-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 SMALA_RS09480 befa7c622a5f22d0514296ecf5d6315e 473 SUPERFAMILY SSF101960 39 470 2.62E-140 T 29-03-2018 SMALA_RS15185 424f4fc30c2adbed636792c5c1e662db 189 SUPERFAMILY SSF51182 14 178 5.56E-41 T 29-03-2018 IPR011051 RmlC-like cupin domain SMALA_RS15185 424f4fc30c2adbed636792c5c1e662db 189 Gene3D G3DSA:2.60.120.10 9 187 4.4E-30 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SMALA_RS15185 424f4fc30c2adbed636792c5c1e662db 189 Pfam PF05995 Cysteine dioxygenase type I 63 166 1.7E-8 T 29-03-2018 IPR010300 Cysteine dioxygenase type I GO:0005506|GO:0016702|GO:0055114 KEGG: 00270+1.13.11.20|KEGG: 00430+1.13.11.20|MetaCyc: PWY-5331|Reactome: R-HSA-1614558 SMALA_RS08235 7187ebfe3dfa3c2ec072bcddeee77f27 755 SUPERFAMILY SSF82866 481 722 6.15E-24 T 29-03-2018 SMALA_RS08235 7187ebfe3dfa3c2ec072bcddeee77f27 755 SUPERFAMILY SSF82866 119 337 7.32E-35 T 29-03-2018 SMALA_RS08235 7187ebfe3dfa3c2ec072bcddeee77f27 755 Pfam PF03176 MMPL family 44 379 8.8E-48 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 SMALA_RS08235 7187ebfe3dfa3c2ec072bcddeee77f27 755 Pfam PF03176 MMPL family 412 724 4.0E-30 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 SMALA_RS08235 7187ebfe3dfa3c2ec072bcddeee77f27 755 Gene3D G3DSA:1.20.1640.10 129 345 1.7E-34 T 29-03-2018 SMALA_RS08235 7187ebfe3dfa3c2ec072bcddeee77f27 755 Gene3D G3DSA:1.20.1640.10 500 721 1.4E-25 T 29-03-2018 SMALA_RS24730 ba698694590ed6bd8a2454461d39e450 461 Pfam PF13476 AAA domain 5 55 2.3E-7 T 29-03-2018 SMALA_RS24730 ba698694590ed6bd8a2454461d39e450 461 SMART SM00382 27 386 1.1E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS24730 ba698694590ed6bd8a2454461d39e450 461 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 263 352 7.4E-17 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 SMALA_RS24730 ba698694590ed6bd8a2454461d39e450 461 Gene3D G3DSA:3.40.50.300 1 87 5.9E-9 T 29-03-2018 SMALA_RS24730 ba698694590ed6bd8a2454461d39e450 461 Gene3D G3DSA:3.40.50.300 200 363 2.3E-15 T 29-03-2018 SMALA_RS24730 ba698694590ed6bd8a2454461d39e450 461 SUPERFAMILY SSF52540 196 357 5.12E-20 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS24730 ba698694590ed6bd8a2454461d39e450 461 SUPERFAMILY SSF52540 13 56 5.12E-20 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS08025 f652282519091e442a5928017be77822 307 SUPERFAMILY SSF51735 7 288 4.24E-41 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS08025 f652282519091e442a5928017be77822 307 Gene3D G3DSA:3.90.25.10 159 283 7.0E-6 T 29-03-2018 SMALA_RS08025 f652282519091e442a5928017be77822 307 Pfam PF13460 NAD(P)H-binding 13 200 1.3E-21 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS08025 f652282519091e442a5928017be77822 307 Gene3D G3DSA:3.40.50.720 2 158 2.2E-15 T 29-03-2018 SMALA_RS01245 56b3de1dc599ff0bf87bc2e75b4672d0 269 Pfam PF13628 Domain of unknown function (DUF4142) 54 188 2.1E-19 T 29-03-2018 IPR025419 Domain of unknown function DUF4142 SMALA_RS01245 56b3de1dc599ff0bf87bc2e75b4672d0 269 Gene3D G3DSA:1.20.1260.10 43 189 3.6E-13 T 29-03-2018 IPR012347 Ferritin-related SMALA_RS04070 12c46bb2f7aa7834994001b38046b28e 108 SUPERFAMILY SSF52833 19 104 3.97E-14 T 29-03-2018 IPR012336 Thioredoxin-like fold SMALA_RS04070 12c46bb2f7aa7834994001b38046b28e 108 Gene3D G3DSA:3.40.30.10 8 71 3.4E-10 T 29-03-2018 SMALA_RS04070 12c46bb2f7aa7834994001b38046b28e 108 Gene3D G3DSA:3.40.30.10 72 108 5.0E-4 T 29-03-2018 SMALA_RS04070 12c46bb2f7aa7834994001b38046b28e 108 Pfam PF00085 Thioredoxin 21 101 1.0E-7 T 29-03-2018 IPR013766 Thioredoxin domain GO:0045454 SMALA_RS25960 1585af41ae2989b78df4267469f9e0ef 355 Gene3D G3DSA:3.90.25.10 178 354 5.2E-35 T 29-03-2018 SMALA_RS25960 1585af41ae2989b78df4267469f9e0ef 355 SUPERFAMILY SSF51735 319 348 6.39E-46 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS25960 1585af41ae2989b78df4267469f9e0ef 355 SUPERFAMILY SSF51735 1 256 6.39E-46 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS25960 1585af41ae2989b78df4267469f9e0ef 355 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 222 9.2E-32 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 SMALA_RS25960 1585af41ae2989b78df4267469f9e0ef 355 Gene3D G3DSA:3.40.50.720 1 177 5.8E-17 T 29-03-2018 SMALA_RS12505 c869447a4add54c8139c239960339b89 310 Gene3D G3DSA:3.40.50.720 1 307 2.3E-59 T 29-03-2018 SMALA_RS12505 c869447a4add54c8139c239960339b89 310 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 197 214 2.7E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS12505 c869447a4add54c8139c239960339b89 310 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 90 101 2.7E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS12505 c869447a4add54c8139c239960339b89 310 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 193 2.7E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS12505 c869447a4add54c8139c239960339b89 310 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 136 152 2.7E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS12505 c869447a4add54c8139c239960339b89 310 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 2.7E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS12505 c869447a4add54c8139c239960339b89 310 SUPERFAMILY SSF51735 13 255 1.67E-53 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS12505 c869447a4add54c8139c239960339b89 310 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 174 193 3.0E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS12505 c869447a4add54c8139c239960339b89 310 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 142 150 3.0E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS12505 c869447a4add54c8139c239960339b89 310 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 90 101 3.0E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS12505 c869447a4add54c8139c239960339b89 310 Pfam PF00106 short chain dehydrogenase 16 216 1.5E-27 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS34830 94e7af0e65168a1d6c24ba0c65029349 353 SUPERFAMILY SSF51735 6 312 2.03E-40 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS34830 94e7af0e65168a1d6c24ba0c65029349 353 Gene3D G3DSA:3.40.50.720 1 314 2.5E-38 T 29-03-2018 SMALA_RS34830 94e7af0e65168a1d6c24ba0c65029349 353 Pfam PF01370 NAD dependent epimerase/dehydratase family 7 222 9.5E-10 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 SMALA_RS28935 42da9ce9d04aaa6ff3fc75e1458db292 391 Gene3D G3DSA:2.40.10.10 146 278 8.7E-11 T 29-03-2018 SMALA_RS28935 42da9ce9d04aaa6ff3fc75e1458db292 391 SUPERFAMILY SSF50494 136 364 1.66E-15 T 29-03-2018 IPR009003 Peptidase S1, PA clan SMALA_RS28935 42da9ce9d04aaa6ff3fc75e1458db292 391 Gene3D G3DSA:2.40.10.10 279 388 1.4E-27 T 29-03-2018 SMALA_RS02060 dd49aa8e4ae5de504531f10c977ed419 266 SMART SM00205 53 263 1.6E-7 T 29-03-2018 IPR001938 Thaumatin SMALA_RS02060 dd49aa8e4ae5de504531f10c977ed419 266 Pfam PF00314 Thaumatin family 57 262 5.4E-27 T 29-03-2018 IPR001938 Thaumatin SMALA_RS02060 dd49aa8e4ae5de504531f10c977ed419 266 SUPERFAMILY SSF49870 52 262 4.06E-30 T 29-03-2018 SMALA_RS02060 dd49aa8e4ae5de504531f10c977ed419 266 Gene3D G3DSA:2.60.110.10 51 265 2.0E-34 T 29-03-2018 SMALA_RS02060 dd49aa8e4ae5de504531f10c977ed419 266 PIRSF PIRSF002703 35 266 1.1E-22 T 29-03-2018 IPR001938 Thaumatin SMALA_RS06280 bc7480d903aa17276dea2b30317f715e 122 Gene3D G3DSA:1.10.10.10 5 113 5.9E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS06280 bc7480d903aa17276dea2b30317f715e 122 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 56 71 1.4E-8 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS06280 bc7480d903aa17276dea2b30317f715e 122 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 71 86 1.4E-8 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS06280 bc7480d903aa17276dea2b30317f715e 122 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 24 39 1.4E-8 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS06280 bc7480d903aa17276dea2b30317f715e 122 SUPERFAMILY SSF46785 12 99 1.5E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS06280 bc7480d903aa17276dea2b30317f715e 122 SMART SM00418 22 100 1.4E-16 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS06280 bc7480d903aa17276dea2b30317f715e 122 Pfam PF12840 Helix-turn-helix domain 23 80 6.1E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS28875 b5ac30da243093a53298dafe95325999 329 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 13 327 4.3E-74 T 29-03-2018 IPR011852 TRAP transporter solute receptor, TAXI family SMALA_RS28875 b5ac30da243093a53298dafe95325999 329 Pfam PF16868 NMT1-like family 46 325 1.5E-50 T 29-03-2018 IPR011852 TRAP transporter solute receptor, TAXI family SMALA_RS28875 b5ac30da243093a53298dafe95325999 329 Gene3D G3DSA:3.40.190.10 40 171 5.8E-9 T 29-03-2018 SMALA_RS28875 b5ac30da243093a53298dafe95325999 329 Gene3D G3DSA:3.40.190.10 178 327 6.4E-34 T 29-03-2018 SMALA_RS28875 b5ac30da243093a53298dafe95325999 329 SUPERFAMILY SSF53850 42 325 2.24E-57 T 29-03-2018 SMALA_RS08150 f8f3c6cd25637d33a893c9518ae8fa5c 433 Gene3D G3DSA:3.40.50.1820 38 426 7.2E-16 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS08150 f8f3c6cd25637d33a893c9518ae8fa5c 433 SUPERFAMILY SSF53474 215 338 2.95E-5 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS06695 1facd097fed951f894fbf19804e84327 570 TIGRFAM TIGR00795 lctP: transporter, lactate permease (LctP) family 15 560 1.0E-130 T 29-03-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 SMALA_RS06695 1facd097fed951f894fbf19804e84327 570 Pfam PF02652 L-lactate permease 16 560 7.8E-136 T 29-03-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 SMALA_RS30095 7328f8a3030f25ce4cfeaaec409cc93f 439 Pfam PF07690 Major Facilitator Superfamily 55 376 7.0E-22 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS30095 7328f8a3030f25ce4cfeaaec409cc93f 439 Gene3D G3DSA:1.20.1250.20 41 239 1.0E-15 T 29-03-2018 SMALA_RS30095 7328f8a3030f25ce4cfeaaec409cc93f 439 PRINTS PR01988 Putative bacilysin exporter bacE signature 177 198 2.2E-5 T 29-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 SMALA_RS30095 7328f8a3030f25ce4cfeaaec409cc93f 439 PRINTS PR01988 Putative bacilysin exporter bacE signature 204 221 2.2E-5 T 29-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 SMALA_RS30095 7328f8a3030f25ce4cfeaaec409cc93f 439 PRINTS PR01988 Putative bacilysin exporter bacE signature 85 103 2.2E-5 T 29-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 SMALA_RS30095 7328f8a3030f25ce4cfeaaec409cc93f 439 PRINTS PR01988 Putative bacilysin exporter bacE signature 49 71 2.2E-5 T 29-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 SMALA_RS30095 7328f8a3030f25ce4cfeaaec409cc93f 439 Gene3D G3DSA:1.20.1250.20 240 438 1.2E-10 T 29-03-2018 SMALA_RS30095 7328f8a3030f25ce4cfeaaec409cc93f 439 SUPERFAMILY SSF103473 36 428 1.11E-30 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS14025 9ddf013db48a5a9fb7466b0d6d8e4265 429 Gene3D G3DSA:3.40.190.10 218 374 1.2E-7 T 29-03-2018 SMALA_RS14025 9ddf013db48a5a9fb7466b0d6d8e4265 429 SUPERFAMILY SSF53850 35 427 1.09E-60 T 29-03-2018 SMALA_RS14025 9ddf013db48a5a9fb7466b0d6d8e4265 429 Pfam PF01547 Bacterial extracellular solute-binding protein 53 337 2.7E-29 T 29-03-2018 IPR006059 Solute-binding family 1 GO:0006810 SMALA_RS14025 9ddf013db48a5a9fb7466b0d6d8e4265 429 Gene3D G3DSA:3.40.190.10 37 217 1.7E-35 T 29-03-2018 SMALA_RS30250 4463f1d2446661478abd19e823c0caf9 381 Gene3D G3DSA:3.40.190.10 61 167 4.5E-9 T 29-03-2018 SMALA_RS30250 4463f1d2446661478abd19e823c0caf9 381 SUPERFAMILY SSF53850 64 295 2.29E-35 T 29-03-2018 SMALA_RS30250 4463f1d2446661478abd19e823c0caf9 381 TIGRFAM TIGR01728 SsuA_fam: ABC transporter, substrate-binding protein, aliphatic sulfonates family 65 361 1.6E-52 T 29-03-2018 IPR010067 Aliphatic sulfonates-binding protein GO:0016020|GO:0042626 SMALA_RS30250 4463f1d2446661478abd19e823c0caf9 381 Pfam PF13379 NMT1-like family 63 300 4.8E-25 T 29-03-2018 SMALA_RS30250 4463f1d2446661478abd19e823c0caf9 381 Gene3D G3DSA:3.40.190.10 168 360 6.8E-29 T 29-03-2018 SMALA_RS33405 144dc475df0508bcd5a53e3cd93ff449 358 Pfam PF00535 Glycosyl transferase family 2 17 140 6.8E-25 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 SMALA_RS33405 144dc475df0508bcd5a53e3cd93ff449 358 SUPERFAMILY SSF53448 15 213 3.47E-40 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS33405 144dc475df0508bcd5a53e3cd93ff449 358 Gene3D G3DSA:3.90.550.10 7 349 1.5E-36 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS23770 f5e20e10d9076416277562337d865284 207 Gene3D G3DSA:3.40.630.30 1 206 2.1E-30 T 29-03-2018 SMALA_RS23770 f5e20e10d9076416277562337d865284 207 SUPERFAMILY SSF55729 7 184 2.47E-41 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS23770 f5e20e10d9076416277562337d865284 207 Pfam PF13302 Acetyltransferase (GNAT) domain 15 161 2.2E-16 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SMALA_RS33075 8683ed3a2c2a4be30385210c8ef84b08 166 Gene3D G3DSA:1.10.260.40 1 71 2.7E-12 T 29-03-2018 SMALA_RS33075 8683ed3a2c2a4be30385210c8ef84b08 166 Pfam PF01381 Helix-turn-helix 13 69 1.3E-8 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS33075 8683ed3a2c2a4be30385210c8ef84b08 166 SMART SM00530 12 69 2.1E-6 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS33075 8683ed3a2c2a4be30385210c8ef84b08 166 SUPERFAMILY SSF47413 4 73 5.04E-9 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS00480 7dfaeef0ed747e1b491ef5d43e635465 325 Gene3D G3DSA:1.20.910.10 72 325 2.4E-27 T 29-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 SMALA_RS00480 7dfaeef0ed747e1b491ef5d43e635465 325 SMART SM01236 159 264 2.1E-31 T 29-03-2018 SMALA_RS00480 7dfaeef0ed747e1b491ef5d43e635465 325 SUPERFAMILY SSF48613 124 293 9.45E-7 T 29-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 SMALA_RS00480 7dfaeef0ed747e1b491ef5d43e635465 325 Pfam PF14518 Iron-containing redox enzyme 127 302 1.9E-43 T 29-03-2018 IPR028201 PqqC-like protein SMALA_RS15065 7333da065f4594b1b6a90898b8f04a1b 112 Hamap MF_00302 ATP-dependent Clp protease adapter protein ClpS [clpS]. 21 112 17.163 T 29-03-2018 IPR022935 ATP-dependent Clp protease adaptor protein ClpS SMALA_RS15065 7333da065f4594b1b6a90898b8f04a1b 112 Gene3D G3DSA:3.30.1390.10 37 108 7.8E-26 T 29-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like SMALA_RS15065 7333da065f4594b1b6a90898b8f04a1b 112 SUPERFAMILY SSF54736 34 109 5.75E-25 T 29-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like SMALA_RS15065 7333da065f4594b1b6a90898b8f04a1b 112 Pfam PF02617 ATP-dependent Clp protease adaptor protein ClpS 37 106 4.6E-22 T 29-03-2018 IPR003769 Adaptor protein ClpS, core GO:0030163 Reactome: R-HSA-983168 SMALA_RS42155 9446aeabff27a2fed2276d509c27eb02 240 SUPERFAMILY SSF51735 4 227 1.34E-40 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS42155 9446aeabff27a2fed2276d509c27eb02 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 2.9E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS42155 9446aeabff27a2fed2276d509c27eb02 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 2.9E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS42155 9446aeabff27a2fed2276d509c27eb02 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 2.9E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS42155 9446aeabff27a2fed2276d509c27eb02 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 2.9E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS42155 9446aeabff27a2fed2276d509c27eb02 240 Pfam PF00106 short chain dehydrogenase 6 189 1.4E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS42155 9446aeabff27a2fed2276d509c27eb02 240 Gene3D G3DSA:3.40.50.720 3 236 1.1E-38 T 29-03-2018 SMALA_RS13850 8b2eb62afa45c5357f4113a8e47fa27b 606 SUPERFAMILY SSF53474 373 526 2.16E-5 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS13850 8b2eb62afa45c5357f4113a8e47fa27b 606 Gene3D G3DSA:1.10.287.1060 10 102 0.0024 T 29-03-2018 SMALA_RS13850 8b2eb62afa45c5357f4113a8e47fa27b 606 Pfam PF06259 Alpha/beta hydrolase 361 529 9.2E-30 T 29-03-2018 IPR010427 Protein of unknown function DUF1023 SMALA_RS13850 8b2eb62afa45c5357f4113a8e47fa27b 606 Gene3D G3DSA:3.40.50.1820 363 606 9.4E-5 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS18375 45fe66b04339ce1d7820c28a95378177 574 Pfam PF00083 Sugar (and other) transporter 115 524 2.2E-44 T 29-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 SMALA_RS18375 45fe66b04339ce1d7820c28a95378177 574 SUPERFAMILY SSF103473 84 523 3.92E-80 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS18375 45fe66b04339ce1d7820c28a95378177 574 Gene3D G3DSA:1.20.1250.20 88 289 1.4E-36 T 29-03-2018 SMALA_RS18375 45fe66b04339ce1d7820c28a95378177 574 Gene3D G3DSA:1.20.1250.20 315 539 6.2E-33 T 29-03-2018 SMALA_RS15280 31b332648984e3d3f0bcc6e3e11951d6 288 SUPERFAMILY SSF46785 9 83 2.73E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS15280 31b332648984e3d3f0bcc6e3e11951d6 288 SMART SM00345 20 79 8.9E-17 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS15280 31b332648984e3d3f0bcc6e3e11951d6 288 Gene3D G3DSA:1.10.10.10 7 81 2.1E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS15280 31b332648984e3d3f0bcc6e3e11951d6 288 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 39 53 4.6E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS15280 31b332648984e3d3f0bcc6e3e11951d6 288 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 53 69 4.6E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS15280 31b332648984e3d3f0bcc6e3e11951d6 288 Pfam PF00392 Bacterial regulatory proteins, gntR family 16 79 2.9E-17 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS02725 3b433c796281768f69d03facbc7926de 843 Pfam PF12704 MacB-like periplasmic core domain 486 682 1.8E-8 T 29-03-2018 IPR025857 MacB-like periplasmic core domain SMALA_RS02725 3b433c796281768f69d03facbc7926de 843 Pfam PF12704 MacB-like periplasmic core domain 17 231 6.3E-17 T 29-03-2018 IPR025857 MacB-like periplasmic core domain SMALA_RS02725 3b433c796281768f69d03facbc7926de 843 Pfam PF02687 FtsX-like permease family 744 835 2.1E-13 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 SMALA_RS02725 3b433c796281768f69d03facbc7926de 843 Pfam PF02687 FtsX-like permease family 292 385 2.5E-14 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 SMALA_RS37575 6061c56b731a132e68f9d1e0f08a3aef 485 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 349 369 - T 29-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 SMALA_RS37575 6061c56b731a132e68f9d1e0f08a3aef 485 Gene3D G3DSA:3.30.420.40 252 480 1.6E-40 T 29-03-2018 SMALA_RS37575 6061c56b731a132e68f9d1e0f08a3aef 485 SUPERFAMILY SSF53067 13 256 1.07E-54 T 29-03-2018 SMALA_RS37575 6061c56b731a132e68f9d1e0f08a3aef 485 TIGRFAM TIGR01312 XylB: xylulokinase 15 474 7.7E-139 T 29-03-2018 IPR006000 Xylulokinase GO:0004856|GO:0005997 KEGG: 00040+2.7.1.17 SMALA_RS37575 6061c56b731a132e68f9d1e0f08a3aef 485 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 13 254 3.1E-67 T 29-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 SMALA_RS37575 6061c56b731a132e68f9d1e0f08a3aef 485 SUPERFAMILY SSF53067 257 474 1.88E-33 T 29-03-2018 SMALA_RS37575 6061c56b731a132e68f9d1e0f08a3aef 485 Gene3D G3DSA:3.30.420.40 8 251 7.7E-74 T 29-03-2018 SMALA_RS37575 6061c56b731a132e68f9d1e0f08a3aef 485 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 316 435 9.8E-16 T 29-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 SMALA_RS37575 6061c56b731a132e68f9d1e0f08a3aef 485 PIRSF PIRSF000538 11 483 1.3E-82 T 29-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 SMALA_RS30640 9a929b64c1a3381633b0c505d3b042f1 280 SMART SM00382 40 233 8.5E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS30640 9a929b64c1a3381633b0c505d3b042f1 280 Pfam PF00005 ABC transporter 31 185 2.9E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS30640 9a929b64c1a3381633b0c505d3b042f1 280 Gene3D G3DSA:3.40.50.300 12 270 7.5E-52 T 29-03-2018 SMALA_RS30640 9a929b64c1a3381633b0c505d3b042f1 280 SUPERFAMILY SSF52540 16 243 7.73E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS30640 9a929b64c1a3381633b0c505d3b042f1 280 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS33045 42cda22e2d0b7a9c9599c3a54fd1f13b 160 Hamap MF_00109 Shikimate kinase [aroK]. 1 156 22.105 T 29-03-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 SMALA_RS33045 42cda22e2d0b7a9c9599c3a54fd1f13b 160 SUPERFAMILY SSF52540 1 155 9.96E-20 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS33045 42cda22e2d0b7a9c9599c3a54fd1f13b 160 PRINTS PR01100 Shikimate kinase family signature 65 74 2.0E-6 T 29-03-2018 SMALA_RS33045 42cda22e2d0b7a9c9599c3a54fd1f13b 160 PRINTS PR01100 Shikimate kinase family signature 19 32 2.0E-6 T 29-03-2018 SMALA_RS33045 42cda22e2d0b7a9c9599c3a54fd1f13b 160 PRINTS PR01100 Shikimate kinase family signature 85 102 2.0E-6 T 29-03-2018 SMALA_RS33045 42cda22e2d0b7a9c9599c3a54fd1f13b 160 PRINTS PR01100 Shikimate kinase family signature 47 55 2.0E-6 T 29-03-2018 SMALA_RS33045 42cda22e2d0b7a9c9599c3a54fd1f13b 160 ProSitePatterns PS01128 Shikimate kinase signature. 48 73 - T 29-03-2018 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 SMALA_RS33045 42cda22e2d0b7a9c9599c3a54fd1f13b 160 Gene3D G3DSA:3.40.50.300 1 160 5.7E-26 T 29-03-2018 SMALA_RS33045 42cda22e2d0b7a9c9599c3a54fd1f13b 160 Pfam PF01202 Shikimate kinase 1 155 5.8E-42 T 29-03-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 SMALA_RS32730 ac48df83ae9444aeac3250996e943e3d 397 Gene3D G3DSA:1.10.260.40 1 82 6.7E-16 T 29-03-2018 SMALA_RS32730 ac48df83ae9444aeac3250996e943e3d 397 SUPERFAMILY SSF47413 6 73 2.95E-14 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS32730 ac48df83ae9444aeac3250996e943e3d 397 Gene3D G3DSA:1.25.40.10 129 375 2.2E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS32730 ac48df83ae9444aeac3250996e943e3d 397 SMART SM00530 10 66 9.5E-9 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS32730 ac48df83ae9444aeac3250996e943e3d 397 Pfam PF13560 Helix-turn-helix domain 7 63 8.4E-11 T 29-03-2018 SMALA_RS27085 8afbb4af797c0ffe212388ae27320b36 216 SUPERFAMILY SSF51219 8 213 1.02E-44 T 29-03-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain SMALA_RS27085 8afbb4af797c0ffe212388ae27320b36 216 Gene3D G3DSA:3.60.160.10 1 216 6.4E-47 T 29-03-2018 IPR002838 Mitochondrial biogenesis protein AIM24 SMALA_RS27085 8afbb4af797c0ffe212388ae27320b36 216 Pfam PF01987 Mitochondrial biogenesis AIM24 4 211 2.0E-33 T 29-03-2018 IPR002838 Mitochondrial biogenesis protein AIM24 SMALA_RS41130 4a5eddbea3dce92631c11e27576072fe 431 Pfam PF13416 Bacterial extracellular solute-binding protein 55 372 2.0E-34 T 29-03-2018 SMALA_RS41130 4a5eddbea3dce92631c11e27576072fe 431 Gene3D G3DSA:3.40.190.10 232 387 1.2E-14 T 29-03-2018 SMALA_RS41130 4a5eddbea3dce92631c11e27576072fe 431 SUPERFAMILY SSF53850 37 426 2.12E-63 T 29-03-2018 SMALA_RS41130 4a5eddbea3dce92631c11e27576072fe 431 Gene3D G3DSA:3.40.190.10 36 231 6.9E-30 T 29-03-2018 SMALA_RS15695 fd5bfd7242440e273d4bda19110f5325 238 Pfam PF00392 Bacterial regulatory proteins, gntR family 5 68 7.0E-16 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS15695 fd5bfd7242440e273d4bda19110f5325 238 Gene3D G3DSA:1.10.10.10 3 70 9.0E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS15695 fd5bfd7242440e273d4bda19110f5325 238 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 28 42 1.2E-5 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS15695 fd5bfd7242440e273d4bda19110f5325 238 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 58 1.2E-5 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS15695 fd5bfd7242440e273d4bda19110f5325 238 SUPERFAMILY SSF64288 56 231 1.37E-22 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMALA_RS15695 fd5bfd7242440e273d4bda19110f5325 238 SMART SM00866 95 231 1.6E-6 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMALA_RS15695 fd5bfd7242440e273d4bda19110f5325 238 SUPERFAMILY SSF46785 5 76 4.92E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS15695 fd5bfd7242440e273d4bda19110f5325 238 Gene3D G3DSA:3.40.1410.10 84 233 2.4E-21 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMALA_RS15695 fd5bfd7242440e273d4bda19110f5325 238 SMART SM00345 9 68 5.8E-15 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS15695 fd5bfd7242440e273d4bda19110f5325 238 Pfam PF07702 UTRA domain 104 227 2.6E-16 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMALA_RS37305 3197160483168ed3539f550358b72e36 332 SMART SM00849 27 234 4.0E-13 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS37305 3197160483168ed3539f550358b72e36 332 Pfam PF00753 Metallo-beta-lactamase superfamily 24 234 7.1E-15 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS37305 3197160483168ed3539f550358b72e36 332 SUPERFAMILY SSF56281 8 275 5.32E-45 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS37305 3197160483168ed3539f550358b72e36 332 Gene3D G3DSA:3.60.15.10 3 262 3.5E-24 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS13520 2ed3202ec77cde566c7810d0d1bd98a8 465 TIGRFAM TIGR03934 TQXA_dom: TQXA domain 119 166 2.2E-16 T 29-03-2018 IPR023849 Uncharacterised domain CHP03934, TQXA SMALA_RS13520 2ed3202ec77cde566c7810d0d1bd98a8 465 Gene3D G3DSA:2.60.40.1310 140 310 0.017 T 29-03-2018 SMALA_RS13520 2ed3202ec77cde566c7810d0d1bd98a8 465 Pfam PF05506 Domain of unknown function (DUF756) 318 388 4.5E-10 T 29-03-2018 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 SMALA_RS13520 2ed3202ec77cde566c7810d0d1bd98a8 465 Gene3D G3DSA:1.20.5.100 426 461 0.0042 T 29-03-2018 SMALA_RS13520 2ed3202ec77cde566c7810d0d1bd98a8 465 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 426 460 2.7E-5 T 29-03-2018 SMALA_RS12460 9796ad76da512ba41b25d6f3e3ffe6e0 699 Gene3D G3DSA:3.50.50.60 305 349 0.0071 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS12460 9796ad76da512ba41b25d6f3e3ffe6e0 699 Gene3D G3DSA:3.50.50.60 131 261 6.4E-27 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS12460 9796ad76da512ba41b25d6f3e3ffe6e0 699 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 137 155 1.8E-18 T 29-03-2018 SMALA_RS12460 9796ad76da512ba41b25d6f3e3ffe6e0 699 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 356 378 1.8E-18 T 29-03-2018 SMALA_RS12460 9796ad76da512ba41b25d6f3e3ffe6e0 699 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 189 207 1.8E-18 T 29-03-2018 SMALA_RS12460 9796ad76da512ba41b25d6f3e3ffe6e0 699 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 15 34 1.8E-18 T 29-03-2018 SMALA_RS12460 9796ad76da512ba41b25d6f3e3ffe6e0 699 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 53 257 2.8E-29 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS12460 9796ad76da512ba41b25d6f3e3ffe6e0 699 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 318 395 2.8E-15 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS12460 9796ad76da512ba41b25d6f3e3ffe6e0 699 Gene3D G3DSA:3.50.50.60 1 130 2.3E-12 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS12460 9796ad76da512ba41b25d6f3e3ffe6e0 699 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 14 36 3.7E-6 T 29-03-2018 SMALA_RS12460 9796ad76da512ba41b25d6f3e3ffe6e0 699 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 189 214 3.7E-6 T 29-03-2018 SMALA_RS12460 9796ad76da512ba41b25d6f3e3ffe6e0 699 Gene3D G3DSA:3.50.50.60 350 405 2.0E-7 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS12460 9796ad76da512ba41b25d6f3e3ffe6e0 699 SUPERFAMILY SSF51905 8 260 8.42E-30 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS12460 9796ad76da512ba41b25d6f3e3ffe6e0 699 SUPERFAMILY SSF51905 317 400 8.42E-30 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS17130 b0ecea84386c1fde157766bd37d064f9 221 SMART SM00943 28 209 5.2E-29 T 29-03-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal SMALA_RS17130 b0ecea84386c1fde157766bd37d064f9 221 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 28 201 4.0E-24 T 29-03-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal SMALA_RS32840 9ede1cc6eb5eb3fb1d2ce137747a0638 241 SMART SM00479 8 189 1.4E-22 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III SMALA_RS32840 9ede1cc6eb5eb3fb1d2ce137747a0638 241 Pfam PF00929 Exonuclease 11 179 3.9E-16 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III SMALA_RS32840 9ede1cc6eb5eb3fb1d2ce137747a0638 241 SUPERFAMILY SSF53098 4 204 8.6E-42 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SMALA_RS32840 9ede1cc6eb5eb3fb1d2ce137747a0638 241 Gene3D G3DSA:3.30.420.10 8 205 1.8E-31 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SMALA_RS12755 54eb6edb0ad2cdf60cb5bb750b5fdf81 316 Gene3D G3DSA:3.40.50.720 1 316 6.6E-44 T 29-03-2018 SMALA_RS12755 54eb6edb0ad2cdf60cb5bb750b5fdf81 316 Pfam PF01370 NAD dependent epimerase/dehydratase family 2 245 2.3E-24 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 SMALA_RS12755 54eb6edb0ad2cdf60cb5bb750b5fdf81 316 SUPERFAMILY SSF51735 2 312 1.68E-52 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS32185 c3b801e52a97867c549939cd3412c2fe 381 SUPERFAMILY SSF56059 128 188 2.28E-6 T 29-03-2018 SMALA_RS32185 c3b801e52a97867c549939cd3412c2fe 381 SUPERFAMILY SSF56059 216 334 2.28E-6 T 29-03-2018 SMALA_RS32185 c3b801e52a97867c549939cd3412c2fe 381 Gene3D G3DSA:3.30.470.20 109 380 5.1E-20 T 29-03-2018 SMALA_RS19670 5504e9aa5ea9ca1032cdcfb1baadde53 205 SUPERFAMILY SSF55729 5 141 1.89E-12 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS19670 5504e9aa5ea9ca1032cdcfb1baadde53 205 Gene3D G3DSA:3.40.630.30 4 191 9.7E-17 T 29-03-2018 SMALA_RS19670 5504e9aa5ea9ca1032cdcfb1baadde53 205 Pfam PF00583 Acetyltransferase (GNAT) family 50 136 2.8E-5 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SMALA_RS12760 2551c7d236bda59704aa4479a94a4a47 197 Gene3D G3DSA:3.40.430.10 110 197 2.1E-13 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 SMALA_RS12760 2551c7d236bda59704aa4479a94a4a47 197 Gene3D G3DSA:3.40.430.10 1 109 7.2E-16 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 SMALA_RS12760 2551c7d236bda59704aa4479a94a4a47 197 Pfam PF01872 RibD C-terminal domain 3 174 1.7E-8 T 29-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 SMALA_RS12760 2551c7d236bda59704aa4479a94a4a47 197 SUPERFAMILY SSF53597 2 193 1.7E-24 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 SMALA_RS27485 47ad6b447d5e3b51da3d57bff77917f2 1734 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1092 1132 5.0E-9 T 29-03-2018 IPR006530 YD repeat SMALA_RS27485 47ad6b447d5e3b51da3d57bff77917f2 1734 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1050 1085 1.1E-6 T 29-03-2018 IPR006530 YD repeat SMALA_RS27485 47ad6b447d5e3b51da3d57bff77917f2 1734 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 862 902 3.9E-8 T 29-03-2018 IPR006530 YD repeat SMALA_RS27485 47ad6b447d5e3b51da3d57bff77917f2 1734 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 882 918 1.4E-7 T 29-03-2018 IPR006530 YD repeat SMALA_RS27485 47ad6b447d5e3b51da3d57bff77917f2 1734 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1009 1049 1.3E-7 T 29-03-2018 IPR006530 YD repeat SMALA_RS27485 47ad6b447d5e3b51da3d57bff77917f2 1734 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1135 1172 1.1E-4 T 29-03-2018 IPR006530 YD repeat SMALA_RS27485 47ad6b447d5e3b51da3d57bff77917f2 1734 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 925 964 4.7E-8 T 29-03-2018 IPR006530 YD repeat SMALA_RS27485 47ad6b447d5e3b51da3d57bff77917f2 1734 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1195 1234 2.2E-4 T 29-03-2018 IPR006530 YD repeat SMALA_RS27485 47ad6b447d5e3b51da3d57bff77917f2 1734 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1409 1440 1.3E-7 T 29-03-2018 IPR006530 YD repeat SMALA_RS27485 47ad6b447d5e3b51da3d57bff77917f2 1734 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 966 1006 1.3E-8 T 29-03-2018 IPR006530 YD repeat SMALA_RS27485 47ad6b447d5e3b51da3d57bff77917f2 1734 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 772 805 3.0E-4 T 29-03-2018 IPR006530 YD repeat SMALA_RS27485 47ad6b447d5e3b51da3d57bff77917f2 1734 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1215 1247 4.7E-4 T 29-03-2018 IPR006530 YD repeat SMALA_RS27485 47ad6b447d5e3b51da3d57bff77917f2 1734 SUPERFAMILY SSF69304 1025 1265 1.63E-6 T 29-03-2018 SMALA_RS27485 47ad6b447d5e3b51da3d57bff77917f2 1734 Pfam PF05593 RHS Repeat 1135 1163 6.0E-7 T 29-03-2018 IPR031325 RHS repeat SMALA_RS27485 47ad6b447d5e3b51da3d57bff77917f2 1734 Pfam PF05593 RHS Repeat 925 958 2.0E-8 T 29-03-2018 IPR031325 RHS repeat SMALA_RS27485 47ad6b447d5e3b51da3d57bff77917f2 1734 Pfam PF05593 RHS Repeat 966 1003 2.9E-5 T 29-03-2018 IPR031325 RHS repeat SMALA_RS27485 47ad6b447d5e3b51da3d57bff77917f2 1734 Pfam PF05593 RHS Repeat 773 804 1.5E-4 T 29-03-2018 IPR031325 RHS repeat SMALA_RS27485 47ad6b447d5e3b51da3d57bff77917f2 1734 Pfam PF05593 RHS Repeat 1050 1086 6.2E-5 T 29-03-2018 IPR031325 RHS repeat SMALA_RS27485 47ad6b447d5e3b51da3d57bff77917f2 1734 Pfam PF05593 RHS Repeat 882 918 9.5E-9 T 29-03-2018 IPR031325 RHS repeat SMALA_RS27485 47ad6b447d5e3b51da3d57bff77917f2 1734 Pfam PF05593 RHS Repeat 1409 1440 1.6E-9 T 29-03-2018 IPR031325 RHS repeat SMALA_RS27485 47ad6b447d5e3b51da3d57bff77917f2 1734 Pfam PF05593 RHS Repeat 1093 1126 1.0E-9 T 29-03-2018 IPR031325 RHS repeat SMALA_RS27485 47ad6b447d5e3b51da3d57bff77917f2 1734 Pfam PF05593 RHS Repeat 988 1023 9.3E-8 T 29-03-2018 IPR031325 RHS repeat SMALA_RS27485 47ad6b447d5e3b51da3d57bff77917f2 1734 Pfam PF05593 RHS Repeat 1196 1230 5.3E-5 T 29-03-2018 IPR031325 RHS repeat SMALA_RS27485 47ad6b447d5e3b51da3d57bff77917f2 1734 Pfam PF05593 RHS Repeat 1215 1250 1.5E-6 T 29-03-2018 IPR031325 RHS repeat SMALA_RS27485 47ad6b447d5e3b51da3d57bff77917f2 1734 Pfam PF05593 RHS Repeat 1009 1045 2.6E-6 T 29-03-2018 IPR031325 RHS repeat SMALA_RS27485 47ad6b447d5e3b51da3d57bff77917f2 1734 Pfam PF03527 RHS protein 1512 1541 1.1E-7 T 29-03-2018 IPR001826 RHS protein SMALA_RS27485 47ad6b447d5e3b51da3d57bff77917f2 1734 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1536 1610 1.4E-22 T 29-03-2018 IPR022385 Rhs repeat-associated core GO:0097264 SMALA_RS27485 47ad6b447d5e3b51da3d57bff77917f2 1734 Gene3D G3DSA:2.130.10.10 901 1193 0.052 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMALA_RS27485 47ad6b447d5e3b51da3d57bff77917f2 1734 Pfam PF13367 Protease prsW family 28 230 2.8E-9 T 29-03-2018 IPR026898 Protease PrsW GO:0008233 SMALA_RS13645 eec7121db2f3182ca1db0639706aac6e 469 Gene3D G3DSA:3.40.50.980 3 139 1.1E-18 T 29-03-2018 SMALA_RS13645 eec7121db2f3182ca1db0639706aac6e 469 Pfam PF00501 AMP-binding enzyme 12 370 1.4E-56 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS13645 eec7121db2f3182ca1db0639706aac6e 469 Gene3D G3DSA:2.30.38.10 292 369 7.0E-15 T 29-03-2018 SMALA_RS13645 eec7121db2f3182ca1db0639706aac6e 469 Gene3D G3DSA:3.40.50.980 140 291 5.5E-32 T 29-03-2018 SMALA_RS13645 eec7121db2f3182ca1db0639706aac6e 469 ProSitePatterns PS00455 Putative AMP-binding domain signature. 134 145 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS13645 eec7121db2f3182ca1db0639706aac6e 469 Gene3D G3DSA:3.30.300.30 370 469 4.9E-11 T 29-03-2018 SMALA_RS13645 eec7121db2f3182ca1db0639706aac6e 469 SUPERFAMILY SSF56801 9 468 1.96E-81 T 29-03-2018 SMALA_RS19530 9c693ecce53ddfd0619145ba646c73bb 427 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 222 417 4.3E-28 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain SMALA_RS19530 9c693ecce53ddfd0619145ba646c73bb 427 Gene3D G3DSA:3.40.50.1110 212 423 3.1E-28 T 29-03-2018 SMALA_RS19530 9c693ecce53ddfd0619145ba646c73bb 427 SUPERFAMILY SSF52266 214 423 1.68E-44 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain SMALA_RS02120 8934778afa86d7c21bc6298660b7b7db 224 SUPERFAMILY SSF109604 19 161 1.26E-15 T 29-03-2018 SMALA_RS02120 8934778afa86d7c21bc6298660b7b7db 224 Pfam PF01966 HD domain 36 142 1.3E-7 T 29-03-2018 IPR006674 HD domain SMALA_RS02120 8934778afa86d7c21bc6298660b7b7db 224 Gene3D G3DSA:1.10.3210.10 22 191 4.1E-13 T 29-03-2018 SMALA_RS04475 c65dbeea57adf936dd5b26aac58f72d6 273 SUPERFAMILY SSF54518 95 262 1.83E-10 T 29-03-2018 IPR025659 Tubby C-terminal-like domain SMALA_RS04475 c65dbeea57adf936dd5b26aac58f72d6 273 Pfam PF03803 Scramblase 82 263 1.3E-17 T 29-03-2018 IPR005552 Scramblase SMALA_RS04475 c65dbeea57adf936dd5b26aac58f72d6 273 Pfam PF10708 Protein of unknown function (DUF2510) 9 43 3.2E-14 T 29-03-2018 IPR018929 Domain of unknown function DUF2510 SMALA_RS06635 30f3702b77a33012d6865feea2ba76c7 122 SUPERFAMILY SSF54593 3 119 5.64E-22 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS06635 30f3702b77a33012d6865feea2ba76c7 122 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 116 2.3E-9 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMALA_RS06635 30f3702b77a33012d6865feea2ba76c7 122 Gene3D G3DSA:3.10.180.10 1 120 7.3E-19 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS08835 b0e43531d1e002a199ed270b49699005 111 Pfam PF01337 Barstar (barnase inhibitor) 12 98 1.2E-24 T 29-03-2018 IPR000468 Barstar (barnase inhibitor) SMALA_RS08835 b0e43531d1e002a199ed270b49699005 111 Gene3D G3DSA:3.30.370.10 9 103 4.2E-27 T 29-03-2018 IPR000468 Barstar (barnase inhibitor) SMALA_RS08835 b0e43531d1e002a199ed270b49699005 111 SUPERFAMILY SSF52038 11 103 3.66E-22 T 29-03-2018 IPR000468 Barstar (barnase inhibitor) SMALA_RS12840 adb1a8d7ef847820ef14fe0bbbfad527 69 SUPERFAMILY SSF88659 43 66 3.01E-5 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS12840 adb1a8d7ef847820ef14fe0bbbfad527 69 Pfam PF13384 Homeodomain-like domain 41 63 5.4E-6 T 29-03-2018 SMALA_RS12840 adb1a8d7ef847820ef14fe0bbbfad527 69 Gene3D G3DSA:1.10.10.10 21 68 3.2E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS15625 6624d06cdc04fd9460d2c016019d20eb 188 Gene3D G3DSA:3.40.50.880 1 188 5.8E-46 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS15625 6624d06cdc04fd9460d2c016019d20eb 188 Pfam PF01965 DJ-1/PfpI family 4 179 2.4E-49 T 29-03-2018 IPR002818 DJ-1/PfpI SMALA_RS15625 6624d06cdc04fd9460d2c016019d20eb 188 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 4 181 4.2E-51 T 29-03-2018 IPR006286 Peptidase C56, PfpI SMALA_RS15625 6624d06cdc04fd9460d2c016019d20eb 188 SUPERFAMILY SSF52317 1 181 3.44E-51 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS19385 9333cffebc86a471777a5c4462e212d5 302 Gene3D G3DSA:3.30.2010.10 60 160 3.5E-23 T 29-03-2018 SMALA_RS19385 9333cffebc86a471777a5c4462e212d5 302 Pfam PF01435 Peptidase family M48 75 290 1.2E-34 T 29-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 SMALA_RS19385 9333cffebc86a471777a5c4462e212d5 302 Hamap MF_00188 Protease HtpX [htpX]. 8 292 25.293 T 29-03-2018 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 SMALA_RS02775 f2b5623514c43358342580c94e319349 255 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 16 194 1.5E-4 T 29-03-2018 SMALA_RS02775 f2b5623514c43358342580c94e319349 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 17 34 3.7E-32 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS02775 f2b5623514c43358342580c94e319349 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 92 103 3.7E-32 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS02775 f2b5623514c43358342580c94e319349 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 182 3.7E-32 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS02775 f2b5623514c43358342580c94e319349 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 184 201 3.7E-32 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS02775 f2b5623514c43358342580c94e319349 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 218 238 3.7E-32 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS02775 f2b5623514c43358342580c94e319349 255 SUPERFAMILY SSF51735 16 254 1.1E-71 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS02775 f2b5623514c43358342580c94e319349 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 24 254 4.0E-55 T 29-03-2018 SMALA_RS02775 f2b5623514c43358342580c94e319349 255 Gene3D G3DSA:3.40.50.720 2 255 1.1E-65 T 29-03-2018 SMALA_RS22300 88b63178ba82e2ebd99b96ede42c5651 672 Pfam PF00361 Proton-conducting membrane transporter 137 413 1.1E-75 T 29-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS22300 88b63178ba82e2ebd99b96ede42c5651 672 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 74 124 5.7E-11 T 29-03-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS22300 88b63178ba82e2ebd99b96ede42c5651 672 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 8 664 1.2E-139 T 29-03-2018 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS22300 88b63178ba82e2ebd99b96ede42c5651 672 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 114 134 7.3E-48 T 29-03-2018 SMALA_RS22300 88b63178ba82e2ebd99b96ede42c5651 672 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 320 332 7.3E-48 T 29-03-2018 SMALA_RS22300 88b63178ba82e2ebd99b96ede42c5651 672 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 161 182 7.3E-48 T 29-03-2018 SMALA_RS22300 88b63178ba82e2ebd99b96ede42c5651 672 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 86 111 7.3E-48 T 29-03-2018 SMALA_RS22300 88b63178ba82e2ebd99b96ede42c5651 672 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 435 454 7.3E-48 T 29-03-2018 SMALA_RS22300 88b63178ba82e2ebd99b96ede42c5651 672 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 252 278 7.3E-48 T 29-03-2018 SMALA_RS22300 88b63178ba82e2ebd99b96ede42c5651 672 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 230 251 7.3E-48 T 29-03-2018 SMALA_RS22300 88b63178ba82e2ebd99b96ede42c5651 672 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 270 292 1.4E-6 T 29-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 SMALA_RS22300 88b63178ba82e2ebd99b96ede42c5651 672 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 88 108 1.4E-6 T 29-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 SMALA_RS22300 88b63178ba82e2ebd99b96ede42c5651 672 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 434 456 1.4E-6 T 29-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 SMALA_RS32740 c54dc6113c207fe2e6fa2c28efb16162 263 Pfam PF01636 Phosphotransferase enzyme family 15 203 1.8E-10 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase SMALA_RS32740 c54dc6113c207fe2e6fa2c28efb16162 263 SUPERFAMILY SSF56112 4 97 1.04E-16 T 29-03-2018 IPR011009 Protein kinase-like domain SMALA_RS32740 c54dc6113c207fe2e6fa2c28efb16162 263 SUPERFAMILY SSF56112 133 215 1.04E-16 T 29-03-2018 IPR011009 Protein kinase-like domain SMALA_RS32740 c54dc6113c207fe2e6fa2c28efb16162 263 Gene3D G3DSA:3.90.1200.10 3 262 1.5E-17 T 29-03-2018 SMALA_RS00300 c6c3a916d7756b22aeef77457c8598e2 149 SUPERFAMILY SSF46785 2 131 5.69E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS00300 c6c3a916d7756b22aeef77457c8598e2 149 Pfam PF02082 Transcriptional regulator 1 80 3.5E-16 T 29-03-2018 IPR000944 Transcription regulator Rrf2-type SMALA_RS00300 c6c3a916d7756b22aeef77457c8598e2 149 Gene3D G3DSA:1.10.10.10 1 134 1.7E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS00300 c6c3a916d7756b22aeef77457c8598e2 149 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 129 7.2E-24 T 29-03-2018 IPR000944 Transcription regulator Rrf2-type SMALA_RS03865 8e4bc16b59476856d1c8e3ee5db49558 153 SUPERFAMILY SSF55874 50 136 1.06E-9 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS03865 8e4bc16b59476856d1c8e3ee5db49558 153 Gene3D G3DSA:3.30.565.10 22 153 1.9E-12 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS03865 8e4bc16b59476856d1c8e3ee5db49558 153 Pfam PF13581 Histidine kinase-like ATPase domain 36 149 3.5E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS40035 dccbc8912992f487616252f91bbff188 257 SUPERFAMILY SSF160467 12 101 2.75E-10 T 29-03-2018 SMALA_RS40035 dccbc8912992f487616252f91bbff188 257 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 11 204 1.9E-42 T 29-03-2018 IPR003833 Carboxyltransferase domain, subdomain C and D SMALA_RS40035 dccbc8912992f487616252f91bbff188 257 Gene3D G3DSA:3.30.1360.40 7 92 3.2E-11 T 29-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 SMALA_RS40035 dccbc8912992f487616252f91bbff188 257 Gene3D G3DSA:2.40.100.10 96 245 1.3E-26 T 29-03-2018 IPR029000 Cyclophilin-like domain SMALA_RS40035 dccbc8912992f487616252f91bbff188 257 SUPERFAMILY SSF50891 98 241 5.69E-28 T 29-03-2018 IPR029000 Cyclophilin-like domain SMALA_RS40035 dccbc8912992f487616252f91bbff188 257 SMART SM00796 10 222 3.0E-19 T 29-03-2018 IPR003833 Carboxyltransferase domain, subdomain C and D SMALA_RS23755 e0b6125656a3cf95fa377f6ed4dce53e 439 SUPERFAMILY SSF63882 19 211 2.35E-47 T 29-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 SMALA_RS23755 e0b6125656a3cf95fa377f6ed4dce53e 439 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 212 347 5.7E-30 T 29-03-2018 IPR001453 MoaB/Mog domain SMALA_RS23755 e0b6125656a3cf95fa377f6ed4dce53e 439 Pfam PF00994 Probable molybdopterin binding domain 216 350 1.8E-25 T 29-03-2018 IPR001453 MoaB/Mog domain SMALA_RS23755 e0b6125656a3cf95fa377f6ed4dce53e 439 SMART SM00852 215 351 1.2E-40 T 29-03-2018 IPR001453 MoaB/Mog domain SMALA_RS23755 e0b6125656a3cf95fa377f6ed4dce53e 439 Pfam PF03453 MoeA N-terminal region (domain I and II) 20 202 7.1E-43 T 29-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 SMALA_RS23755 e0b6125656a3cf95fa377f6ed4dce53e 439 Gene3D G3DSA:2.40.340.10 363 439 1.1E-19 T 29-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 SMALA_RS23755 e0b6125656a3cf95fa377f6ed4dce53e 439 Gene3D G3DSA:3.40.980.10 198 361 2.1E-56 T 29-03-2018 IPR001453 MoaB/Mog domain SMALA_RS23755 e0b6125656a3cf95fa377f6ed4dce53e 439 SUPERFAMILY SSF53218 211 354 2.36E-39 T 29-03-2018 IPR001453 MoaB/Mog domain SMALA_RS23755 e0b6125656a3cf95fa377f6ed4dce53e 439 Pfam PF03454 MoeA C-terminal region (domain IV) 374 438 2.2E-16 T 29-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 SMALA_RS23755 e0b6125656a3cf95fa377f6ed4dce53e 439 Gene3D G3DSA:3.90.105.10 165 197 2.2E-11 T 29-03-2018 SMALA_RS23755 e0b6125656a3cf95fa377f6ed4dce53e 439 SUPERFAMILY SSF63867 361 438 2.35E-15 T 29-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 SMALA_RS23755 e0b6125656a3cf95fa377f6ed4dce53e 439 Gene3D G3DSA:2.170.190.11 61 164 1.5E-29 T 29-03-2018 SMALA_RS11305 f33c05de2082f292f354e4a5e8936e2d 444 Gene3D G3DSA:3.30.565.10 313 444 8.1E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS11305 f33c05de2082f292f354e4a5e8936e2d 444 SUPERFAMILY SSF55874 345 441 1.12E-10 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS11305 f33c05de2082f292f354e4a5e8936e2d 444 Pfam PF07730 Histidine kinase 230 295 1.1E-13 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMALA_RS04990 54ca3bac1f69a51b9dcaa495da761499 258 Gene3D G3DSA:3.90.850.10 1 258 2.3E-41 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 SMALA_RS04990 54ca3bac1f69a51b9dcaa495da761499 258 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 103 257 6.0E-10 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 SMALA_RS04990 54ca3bac1f69a51b9dcaa495da761499 258 SUPERFAMILY SSF56529 1 257 6.3E-56 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 SMALA_RS13295 92ae539d3cbb94fdc7ba33c1cf74b19b 277 SUPERFAMILY SSF53474 19 272 5.08E-26 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS13295 92ae539d3cbb94fdc7ba33c1cf74b19b 277 Gene3D G3DSA:3.40.50.1820 3 272 8.0E-32 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS06155 40781ec2658eb3f7d74eb67561d3d519 280 SUPERFAMILY SSF47413 29 80 6.57E-7 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS06155 40781ec2658eb3f7d74eb67561d3d519 280 SMART SM00530 9 81 1.8E-6 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS06155 40781ec2658eb3f7d74eb67561d3d519 280 Pfam PF13560 Helix-turn-helix domain 5 84 3.7E-15 T 29-03-2018 SMALA_RS06155 40781ec2658eb3f7d74eb67561d3d519 280 Gene3D G3DSA:1.10.260.40 1 81 1.1E-13 T 29-03-2018 SMALA_RS04200 794ba9005faf7f6d065e2bfda2764041 311 Gene3D G3DSA:3.30.2010.10 106 200 2.8E-13 T 29-03-2018 SMALA_RS04200 794ba9005faf7f6d065e2bfda2764041 311 Pfam PF01435 Peptidase family M48 141 217 5.2E-9 T 29-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 SMALA_RS00795 10825c0c98aaf6eef0815f58596999d7 341 Gene3D G3DSA:3.40.190.10 139 340 1.4E-22 T 29-03-2018 SMALA_RS00795 10825c0c98aaf6eef0815f58596999d7 341 SUPERFAMILY SSF53850 35 279 1.09E-31 T 29-03-2018 SMALA_RS00795 10825c0c98aaf6eef0815f58596999d7 341 Gene3D G3DSA:3.40.190.10 33 138 1.5E-11 T 29-03-2018 SMALA_RS00795 10825c0c98aaf6eef0815f58596999d7 341 Pfam PF09084 NMT1/THI5 like 50 264 7.7E-22 T 29-03-2018 IPR015168 SsuA/THI5-like SMALA_RS00800 7e2fa4d799ed3870cebbd0d5175e1409 291 SUPERFAMILY SSF161098 86 267 3.4E-30 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS00800 7e2fa4d799ed3870cebbd0d5175e1409 291 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 106 279 2.9E-23 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS00800 7e2fa4d799ed3870cebbd0d5175e1409 291 Gene3D G3DSA:1.10.3720.10 33 284 2.6E-23 T 29-03-2018 SMALA_RS42810 cc4a46b275f0524198830bac50da8a3f 286 Pfam PF01909 Nucleotidyltransferase domain 27 57 8.0E-5 T 29-03-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 SMALA_RS42810 cc4a46b275f0524198830bac50da8a3f 286 SUPERFAMILY SSF81301 3 65 2.77E-6 T 29-03-2018 SMALA_RS42810 cc4a46b275f0524198830bac50da8a3f 286 Gene3D G3DSA:3.30.460.10 1 159 5.0E-6 T 29-03-2018 SMALA_RS33860 68e8bfb6aad73f454345ba28e26c5167 106 Pfam PF05336 L-rhamnose mutarotase 3 105 2.8E-32 T 29-03-2018 IPR008000 Rhamnose/fucose mutarotase GO:0005737|GO:0016857 SMALA_RS33860 68e8bfb6aad73f454345ba28e26c5167 106 SUPERFAMILY SSF54909 1 105 2.15E-34 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel SMALA_RS33860 68e8bfb6aad73f454345ba28e26c5167 106 Gene3D G3DSA:3.30.70.100 4 96 1.2E-4 T 29-03-2018 SMALA_RS39725 6a56d3f414d46c3d99478ab4d3c7fe23 223 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 65 3.0E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS39725 6a56d3f414d46c3d99478ab4d3c7fe23 223 SUPERFAMILY SSF46689 7 86 1.08E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS39725 6a56d3f414d46c3d99478ab4d3c7fe23 223 Gene3D G3DSA:1.10.357.10 2 223 4.2E-26 T 29-03-2018 SMALA_RS26030 68e29e350d12628286f5741c8bfc4c0c 120 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 25 109 15.034 T 29-03-2018 IPR003482 Transcription factor WhiB SMALA_RS26030 68e29e350d12628286f5741c8bfc4c0c 120 ProSitePatterns PS00354 HMG-I and HMG-Y DNA-binding domain (A+T-hook). 105 115 - T 29-03-2018 IPR000637 HMG-I/HMG-Y, DNA-binding, conserved site GO:0006355 SMALA_RS26030 68e29e350d12628286f5741c8bfc4c0c 120 Pfam PF02467 Transcription factor WhiB 47 95 4.2E-15 T 29-03-2018 IPR034768 WhiB-like iron-sulfur binding domain SMALA_RS42140 1a518f215e25546d5df93a7dc248313e 256 Gene3D G3DSA:3.40.50.720 2 205 4.7E-41 T 29-03-2018 SMALA_RS42140 1a518f215e25546d5df93a7dc248313e 256 Pfam PF00106 short chain dehydrogenase 20 204 3.6E-32 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS42140 1a518f215e25546d5df93a7dc248313e 256 SUPERFAMILY SSF51735 17 243 1.41E-44 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS42140 1a518f215e25546d5df93a7dc248313e 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 191 1.0E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS42140 1a518f215e25546d5df93a7dc248313e 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 20 37 1.0E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS42140 1a518f215e25546d5df93a7dc248313e 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 95 106 1.0E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS42140 1a518f215e25546d5df93a7dc248313e 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 143 159 1.0E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS34215 59642cad5a7cb64996d6ba608ed63d69 204 Pfam PF05331 Protein of unknown function (DUF742) 95 203 1.7E-33 T 29-03-2018 IPR007995 Protein of unknown function DUF742 SMALA_RS34215 59642cad5a7cb64996d6ba608ed63d69 204 Gene3D G3DSA:1.10.10.10 83 198 7.9E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS23820 476c91fd6a074201dd1c7c2b5ea7a53c 322 Gene3D G3DSA:3.40.50.1820 21 302 6.4E-48 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS23820 476c91fd6a074201dd1c7c2b5ea7a53c 322 PRINTS PR00111 Alpha/beta hydrolase fold signature 243 257 5.7E-8 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS23820 476c91fd6a074201dd1c7c2b5ea7a53c 322 PRINTS PR00111 Alpha/beta hydrolase fold signature 115 128 5.7E-8 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS23820 476c91fd6a074201dd1c7c2b5ea7a53c 322 PRINTS PR00111 Alpha/beta hydrolase fold signature 68 83 5.7E-8 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS23820 476c91fd6a074201dd1c7c2b5ea7a53c 322 Pfam PF12697 Alpha/beta hydrolase family 45 290 3.3E-20 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS23820 476c91fd6a074201dd1c7c2b5ea7a53c 322 SUPERFAMILY SSF53474 23 297 4.69E-53 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS06540 fa9d70d8be7fcac9a75b4cfd4f25f446 182 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 75 103 2.1E-6 T 29-03-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal SMALA_RS06540 fa9d70d8be7fcac9a75b4cfd4f25f446 182 SUPERFAMILY SSF50249 73 159 1.66E-6 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMALA_RS10075 488a2b94bcdee3f8975602a9d65448cc 441 PRINTS PR00083 Histidinol dehydrogenase signature 137 163 1.1E-79 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 SMALA_RS10075 488a2b94bcdee3f8975602a9d65448cc 441 PRINTS PR00083 Histidinol dehydrogenase signature 204 229 1.1E-79 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 SMALA_RS10075 488a2b94bcdee3f8975602a9d65448cc 441 PRINTS PR00083 Histidinol dehydrogenase signature 233 254 1.1E-79 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 SMALA_RS10075 488a2b94bcdee3f8975602a9d65448cc 441 PRINTS PR00083 Histidinol dehydrogenase signature 174 200 1.1E-79 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 SMALA_RS10075 488a2b94bcdee3f8975602a9d65448cc 441 PRINTS PR00083 Histidinol dehydrogenase signature 367 385 1.1E-79 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 SMALA_RS10075 488a2b94bcdee3f8975602a9d65448cc 441 PRINTS PR00083 Histidinol dehydrogenase signature 255 274 1.1E-79 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 SMALA_RS10075 488a2b94bcdee3f8975602a9d65448cc 441 PRINTS PR00083 Histidinol dehydrogenase signature 326 351 1.1E-79 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 SMALA_RS10075 488a2b94bcdee3f8975602a9d65448cc 441 PRINTS PR00083 Histidinol dehydrogenase signature 36 60 1.1E-79 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 SMALA_RS10075 488a2b94bcdee3f8975602a9d65448cc 441 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 36 432 6.3E-140 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 SMALA_RS10075 488a2b94bcdee3f8975602a9d65448cc 441 Gene3D G3DSA:3.40.50.1980 230 377 2.5E-57 T 29-03-2018 SMALA_RS10075 488a2b94bcdee3f8975602a9d65448cc 441 SUPERFAMILY SSF53720 28 435 1.71E-70 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMALA_RS10075 488a2b94bcdee3f8975602a9d65448cc 441 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 5 433 38.305 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 SMALA_RS10075 488a2b94bcdee3f8975602a9d65448cc 441 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 233 265 - T 29-03-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 SMALA_RS10075 488a2b94bcdee3f8975602a9d65448cc 441 Gene3D G3DSA:3.40.50.1980 29 229 1.3E-83 T 29-03-2018 SMALA_RS10075 488a2b94bcdee3f8975602a9d65448cc 441 PIRSF PIRSF000099 12 436 3.8E-156 T 29-03-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 SMALA_RS10075 488a2b94bcdee3f8975602a9d65448cc 441 Pfam PF00815 Histidinol dehydrogenase 23 433 1.8E-155 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 SMALA_RS16245 2cab5585f45e9a45817bb9cef1835daa 196 Gene3D G3DSA:3.40.50.300 14 196 4.0E-21 T 29-03-2018 SMALA_RS16245 2cab5585f45e9a45817bb9cef1835daa 196 Pfam PF03029 Conserved hypothetical ATP binding protein 25 191 2.8E-22 T 29-03-2018 IPR004130 GPN-loop GTPase SMALA_RS16245 2cab5585f45e9a45817bb9cef1835daa 196 SUPERFAMILY SSF52540 21 194 1.91E-21 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS34340 41a73252aa4637083d6e338f13a92043 492 Gene3D G3DSA:3.30.420.40 244 492 4.9E-60 T 29-03-2018 SMALA_RS34340 41a73252aa4637083d6e338f13a92043 492 SUPERFAMILY SSF53067 252 477 2.07E-57 T 29-03-2018 SMALA_RS34340 41a73252aa4637083d6e338f13a92043 492 PIRSF PIRSF000538 3 488 1.0E-119 T 29-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 SMALA_RS34340 41a73252aa4637083d6e338f13a92043 492 SUPERFAMILY SSF53067 6 250 3.89E-53 T 29-03-2018 SMALA_RS34340 41a73252aa4637083d6e338f13a92043 492 Gene3D G3DSA:3.30.420.40 1 243 9.2E-62 T 29-03-2018 SMALA_RS34340 41a73252aa4637083d6e338f13a92043 492 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 352 372 - T 29-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 SMALA_RS34340 41a73252aa4637083d6e338f13a92043 492 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 6 245 2.7E-43 T 29-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 SMALA_RS34340 41a73252aa4637083d6e338f13a92043 492 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 257 437 2.6E-35 T 29-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 SMALA_RS29870 97dd9dfa5d584056ab7bb709ed5c3377 393 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 1.1E-28 T 29-03-2018 SMALA_RS29870 97dd9dfa5d584056ab7bb709ed5c3377 393 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 280 295 1.1E-28 T 29-03-2018 SMALA_RS29870 97dd9dfa5d584056ab7bb709ed5c3377 393 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 153 168 1.1E-28 T 29-03-2018 SMALA_RS29870 97dd9dfa5d584056ab7bb709ed5c3377 393 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 295 311 1.1E-28 T 29-03-2018 SMALA_RS29870 97dd9dfa5d584056ab7bb709ed5c3377 393 SUPERFAMILY SSF54373 177 277 1.41E-37 T 29-03-2018 SMALA_RS29870 97dd9dfa5d584056ab7bb709ed5c3377 393 SUPERFAMILY SSF51905 276 390 1.87E-54 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS29870 97dd9dfa5d584056ab7bb709ed5c3377 393 SUPERFAMILY SSF51905 1 174 1.87E-54 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS29870 97dd9dfa5d584056ab7bb709ed5c3377 393 Gene3D G3DSA:3.30.9.10 310 390 1.8E-15 T 29-03-2018 SMALA_RS29870 97dd9dfa5d584056ab7bb709ed5c3377 393 Gene3D G3DSA:3.30.9.10 173 286 7.7E-53 T 29-03-2018 SMALA_RS29870 97dd9dfa5d584056ab7bb709ed5c3377 393 Gene3D G3DSA:3.50.50.60 3 172 6.2E-15 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS29870 97dd9dfa5d584056ab7bb709ed5c3377 393 Pfam PF01494 FAD binding domain 3 345 3.4E-79 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 SMALA_RS30910 dc18797eda672f3dcfb3448d308ba68b 344 Gene3D G3DSA:3.20.20.70 38 318 8.8E-44 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS30910 dc18797eda672f3dcfb3448d308ba68b 344 Pfam PF04055 Radical SAM superfamily 62 234 9.9E-10 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 SMALA_RS30910 dc18797eda672f3dcfb3448d308ba68b 344 SUPERFAMILY SSF102114 61 280 9.42E-12 T 29-03-2018 SMALA_RS41720 d2eada1e2b13757f48534ea26d8d54f2 298 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 160 282 3.6E-11 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS41720 d2eada1e2b13757f48534ea26d8d54f2 298 Gene3D G3DSA:1.10.3720.10 13 291 4.8E-28 T 29-03-2018 SMALA_RS41720 d2eada1e2b13757f48534ea26d8d54f2 298 SUPERFAMILY SSF161098 21 287 7.01E-33 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS05635 338533567013ad575058407dcd262caa 248 Gene3D G3DSA:3.40.50.720 1 45 1.5E-9 T 29-03-2018 SMALA_RS05635 338533567013ad575058407dcd262caa 248 Gene3D G3DSA:3.40.50.720 46 248 3.8E-62 T 29-03-2018 SMALA_RS05635 338533567013ad575058407dcd262caa 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 4.7E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS05635 338533567013ad575058407dcd262caa 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 4.7E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS05635 338533567013ad575058407dcd262caa 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 4.7E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS05635 338533567013ad575058407dcd262caa 248 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 245 6.7E-70 T 29-03-2018 SMALA_RS05635 338533567013ad575058407dcd262caa 248 SUPERFAMILY SSF51735 1 246 1.29E-80 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS05635 338533567013ad575058407dcd262caa 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 1.3E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS05635 338533567013ad575058407dcd262caa 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.3E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS05635 338533567013ad575058407dcd262caa 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 1.3E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS05635 338533567013ad575058407dcd262caa 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 1.3E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS05635 338533567013ad575058407dcd262caa 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.3E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS05635 338533567013ad575058407dcd262caa 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 1.3E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS05635 338533567013ad575058407dcd262caa 248 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMALA_RS16900 3598f3ef8fb00f55dbfc7b13bc836769 394 SMART SM00327 218 377 0.0022 T 29-03-2018 IPR002035 von Willebrand factor, type A SMALA_RS16900 3598f3ef8fb00f55dbfc7b13bc836769 394 SUPERFAMILY SSF53300 217 379 3.41E-23 T 29-03-2018 IPR002035 von Willebrand factor, type A SMALA_RS16900 3598f3ef8fb00f55dbfc7b13bc836769 394 Pfam PF05762 VWA domain containing CoxE-like protein 156 375 2.9E-60 T 29-03-2018 IPR008912 Uncharacterised protein family CoxE-like SMALA_RS16900 3598f3ef8fb00f55dbfc7b13bc836769 394 Gene3D G3DSA:3.40.50.410 177 365 2.3E-15 T 29-03-2018 IPR002035 von Willebrand factor, type A SMALA_RS06295 97d21ae234390b0cf6a09af7c131a71b 509 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 390 472 2.2E-15 T 29-03-2018 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain SMALA_RS06295 97d21ae234390b0cf6a09af7c131a71b 509 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 111 282 8.8E-39 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain SMALA_RS06295 97d21ae234390b0cf6a09af7c131a71b 509 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 112 281 4.8E-41 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain SMALA_RS00900 7110f347585a0a777e5cd224dbe12d34 136 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 48 66 - T 29-03-2018 IPR030489 Transcription regulator Rrf2-type, conserved site SMALA_RS00900 7110f347585a0a777e5cd224dbe12d34 136 SUPERFAMILY SSF46785 3 132 6.65E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS00900 7110f347585a0a777e5cd224dbe12d34 136 Gene3D G3DSA:1.10.10.10 1 136 1.3E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS00900 7110f347585a0a777e5cd224dbe12d34 136 Pfam PF02082 Transcriptional regulator 1 82 7.6E-26 T 29-03-2018 IPR000944 Transcription regulator Rrf2-type SMALA_RS00900 7110f347585a0a777e5cd224dbe12d34 136 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 130 1.0E-30 T 29-03-2018 IPR000944 Transcription regulator Rrf2-type SMALA_RS42360 7479c18f5960b2ee1705a642af97b54c 280 Pfam PF13560 Helix-turn-helix domain 16 95 1.4E-15 T 29-03-2018 SMALA_RS42360 7479c18f5960b2ee1705a642af97b54c 280 SMART SM00530 36 92 6.8E-7 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS42360 7479c18f5960b2ee1705a642af97b54c 280 Gene3D G3DSA:1.10.260.40 7 107 1.2E-13 T 29-03-2018 SMALA_RS42360 7479c18f5960b2ee1705a642af97b54c 280 SUPERFAMILY SSF47413 28 92 5.04E-8 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS22265 8036682fd8d63d2325c065f3ab3fda4b 140 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 41 139 7.0E-31 T 29-03-2018 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS22265 8036682fd8d63d2325c065f3ab3fda4b 140 Hamap MF_01394 NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic [ndhC]. 21 140 16.574 T 29-03-2018 IPR023043 NAD(P)H-quinone oxidoreductase subunit 3, bacterial/plastid GO:0016651|GO:0055114 SMALA_RS24735 391cb2d9427adcda2bd7027fcb78e5ed 252 Gene3D G3DSA:3.40.1800.10 39 116 4.3E-8 T 29-03-2018 SMALA_RS24735 391cb2d9427adcda2bd7027fcb78e5ed 252 SMART SM00507 52 102 3.4E-4 T 29-03-2018 IPR003615 HNH nuclease SMALA_RS36635 4b2aec37ef9d9064f03c6dcbe4ba9f87 797 Pfam PF13432 Tetratricopeptide repeat 710 771 3.6E-7 T 29-03-2018 SMALA_RS36635 4b2aec37ef9d9064f03c6dcbe4ba9f87 797 Pfam PF13432 Tetratricopeptide repeat 547 595 7.8E-7 T 29-03-2018 SMALA_RS36635 4b2aec37ef9d9064f03c6dcbe4ba9f87 797 Pfam PF13432 Tetratricopeptide repeat 614 663 8.1E-4 T 29-03-2018 SMALA_RS36635 4b2aec37ef9d9064f03c6dcbe4ba9f87 797 SUPERFAMILY SSF48452 599 774 5.69E-39 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS36635 4b2aec37ef9d9064f03c6dcbe4ba9f87 797 SMART SM00028 534 567 0.7 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS36635 4b2aec37ef9d9064f03c6dcbe4ba9f87 797 SMART SM00028 602 635 27.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS36635 4b2aec37ef9d9064f03c6dcbe4ba9f87 797 SMART SM00028 704 737 0.0036 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS36635 4b2aec37ef9d9064f03c6dcbe4ba9f87 797 SMART SM00028 636 669 0.049 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS36635 4b2aec37ef9d9064f03c6dcbe4ba9f87 797 SMART SM00028 670 703 13.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS36635 4b2aec37ef9d9064f03c6dcbe4ba9f87 797 SMART SM00028 568 601 13.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS36635 4b2aec37ef9d9064f03c6dcbe4ba9f87 797 SMART SM00028 738 771 0.0019 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SMALA_RS36635 4b2aec37ef9d9064f03c6dcbe4ba9f87 797 Gene3D G3DSA:1.20.120.420 738 791 9.7E-9 T 29-03-2018 IPR027363 Methylthioribose-1-phosphate isomerase-like, N-terminal domain KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 SMALA_RS36635 4b2aec37ef9d9064f03c6dcbe4ba9f87 797 Gene3D G3DSA:1.25.40.10 674 723 1.3E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS36635 4b2aec37ef9d9064f03c6dcbe4ba9f87 797 Gene3D G3DSA:1.10.287.1110 724 737 1.4E-6 T 29-03-2018 SMALA_RS36635 4b2aec37ef9d9064f03c6dcbe4ba9f87 797 Gene3D G3DSA:1.10.287.1110 547 566 8.4E-4 T 29-03-2018 SMALA_RS36635 4b2aec37ef9d9064f03c6dcbe4ba9f87 797 Gene3D G3DSA:3.40.50.300 2 240 1.3E-6 T 29-03-2018 SMALA_RS36635 4b2aec37ef9d9064f03c6dcbe4ba9f87 797 SUPERFAMILY SSF52540 209 312 1.84E-8 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS36635 4b2aec37ef9d9064f03c6dcbe4ba9f87 797 SUPERFAMILY SSF52540 13 91 1.84E-8 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS36635 4b2aec37ef9d9064f03c6dcbe4ba9f87 797 Gene3D G3DSA:1.25.40.10 567 619 1.6E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS36635 4b2aec37ef9d9064f03c6dcbe4ba9f87 797 SUPERFAMILY SSF48452 534 632 1.38E-17 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS36635 4b2aec37ef9d9064f03c6dcbe4ba9f87 797 Gene3D G3DSA:1.25.40.10 620 673 6.6E-13 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS36635 4b2aec37ef9d9064f03c6dcbe4ba9f87 797 Pfam PF13191 AAA ATPase domain 13 192 5.7E-8 T 29-03-2018 SMALA_RS38785 4edd5d73020620221526c2838bc476a1 471 Pfam PF01425 Amidase 27 449 1.9E-105 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMALA_RS38785 4edd5d73020620221526c2838bc476a1 471 Gene3D G3DSA:3.90.1300.10 3 471 1.7E-137 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMALA_RS38785 4edd5d73020620221526c2838bc476a1 471 ProSitePatterns PS00571 Amidases signature. 155 186 - T 29-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 SMALA_RS38785 4edd5d73020620221526c2838bc476a1 471 SUPERFAMILY SSF75304 7 457 5.76E-131 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMALA_RS35555 0c348b80349ca03ee3acaf1b4f7d04cc 454 Gene3D G3DSA:3.40.50.1580 10 266 4.5E-38 T 29-03-2018 SMALA_RS35555 0c348b80349ca03ee3acaf1b4f7d04cc 454 SUPERFAMILY SSF53167 12 256 3.67E-31 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 SMALA_RS35555 0c348b80349ca03ee3acaf1b4f7d04cc 454 Pfam PF01048 Phosphorylase superfamily 13 252 6.4E-20 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 SMALA_RS35125 08b7f5ae1c27ec810fbc96a67473a7fd 275 SUPERFAMILY SSF161098 6 275 4.58E-48 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS35125 08b7f5ae1c27ec810fbc96a67473a7fd 275 Gene3D G3DSA:1.10.3720.10 1 263 3.9E-31 T 29-03-2018 SMALA_RS35125 08b7f5ae1c27ec810fbc96a67473a7fd 275 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 102 265 1.0E-11 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS08685 fe82327d012f1191d1ec63ad668af32b 226 Gene3D G3DSA:1.10.10.10 8 95 1.5E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS08685 fe82327d012f1191d1ec63ad668af32b 226 PIRSF PIRSF019345 4 215 6.6E-53 T 29-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 SMALA_RS08685 fe82327d012f1191d1ec63ad668af32b 226 SUPERFAMILY SSF46785 96 169 8.58E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS08685 fe82327d012f1191d1ec63ad668af32b 226 SUPERFAMILY SSF46785 15 91 4.63E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS08685 fe82327d012f1191d1ec63ad668af32b 226 Gene3D G3DSA:1.10.10.10 96 186 4.6E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS08685 fe82327d012f1191d1ec63ad668af32b 226 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 18 181 4.5E-29 T 29-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 SMALA_RS08685 fe82327d012f1191d1ec63ad668af32b 226 Pfam PF04079 Segregation and condensation complex subunit ScpB 21 178 3.0E-56 T 29-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 SMALA_RS15375 164c472f9282b4d99aecc75f68577f02 69 PIRSF PIRSF002599 1 68 8.6E-26 T 29-03-2018 IPR012156 Cold shock, CspA GO:0003676 SMALA_RS15375 164c472f9282b4d99aecc75f68577f02 69 PRINTS PR00050 Cold shock protein signature 40 58 2.8E-17 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMALA_RS15375 164c472f9282b4d99aecc75f68577f02 69 PRINTS PR00050 Cold shock protein signature 25 34 2.8E-17 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMALA_RS15375 164c472f9282b4d99aecc75f68577f02 69 PRINTS PR00050 Cold shock protein signature 4 19 2.8E-17 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMALA_RS15375 164c472f9282b4d99aecc75f68577f02 69 SUPERFAMILY SSF50249 1 67 3.21E-25 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMALA_RS15375 164c472f9282b4d99aecc75f68577f02 69 SMART SM00357 3 67 8.2E-30 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 SMALA_RS15375 164c472f9282b4d99aecc75f68577f02 69 Gene3D G3DSA:2.40.50.140 1 69 3.0E-28 T 29-03-2018 SMALA_RS15375 164c472f9282b4d99aecc75f68577f02 69 Pfam PF00313 'Cold-shock' DNA-binding domain 3 66 4.3E-30 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMALA_RS15375 164c472f9282b4d99aecc75f68577f02 69 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 29-03-2018 IPR019844 Cold-shock conserved site SMALA_RS14930 79b8a02d864ab1a7911502d4b13e155b 223 Pfam PF02096 60Kd inner membrane protein 33 222 4.3E-28 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 SMALA_RS14930 79b8a02d864ab1a7911502d4b13e155b 223 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 32 222 2.2E-31 T 29-03-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal SMALA_RS36340 c623e368af728225b9c92dd446deaea2 116 SUPERFAMILY SSF54909 1 104 3.49E-22 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel SMALA_RS36340 c623e368af728225b9c92dd446deaea2 116 Pfam PF05336 L-rhamnose mutarotase 2 106 1.1E-19 T 29-03-2018 IPR008000 Rhamnose/fucose mutarotase GO:0005737|GO:0016857 SMALA_RS33540 7b14d806f193a2f95bf480a737c7777f 291 SUPERFAMILY SSF53474 1 274 3.56E-57 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS33540 7b14d806f193a2f95bf480a737c7777f 291 Gene3D G3DSA:3.40.50.1820 2 276 6.1E-50 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS33540 7b14d806f193a2f95bf480a737c7777f 291 Pfam PF12697 Alpha/beta hydrolase family 22 268 3.0E-20 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS27440 fd95e37858143fa90e503ec287f6d1ea 404 Pfam PF03734 L,D-transpeptidase catalytic domain 249 352 2.6E-12 T 29-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 SMALA_RS27440 fd95e37858143fa90e503ec287f6d1ea 404 SUPERFAMILY SSF141523 251 378 8.37E-22 T 29-03-2018 SMALA_RS27440 fd95e37858143fa90e503ec287f6d1ea 404 Gene3D G3DSA:2.60.40.10 50 141 3.0E-4 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS27440 fd95e37858143fa90e503ec287f6d1ea 404 Gene3D G3DSA:2.40.440.10 243 380 1.5E-25 T 29-03-2018 SMALA_RS10425 e61277d0e18327f7e3b93b87787e40a3 271 Pfam PF12146 Serine aminopeptidase, S33 19 229 1.0E-22 T 29-03-2018 IPR022742 Serine aminopeptidase, S33 SMALA_RS10425 e61277d0e18327f7e3b93b87787e40a3 271 SUPERFAMILY SSF53474 13 245 2.04E-38 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS10425 e61277d0e18327f7e3b93b87787e40a3 271 Gene3D G3DSA:3.40.50.1820 4 247 3.0E-41 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS10425 e61277d0e18327f7e3b93b87787e40a3 271 PIRSF PIRSF017388 1 248 9.9E-74 T 29-03-2018 IPR012354 Esterase/lipase GO:0052689 SMALA_RS41145 0859d1be8608289648cb8a79b6f9b729 359 SUPERFAMILY SSF75005 27 356 9.1E-47 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain SMALA_RS41145 0859d1be8608289648cb8a79b6f9b729 359 Pfam PF04041 beta-1,4-mannooligosaccharide phosphorylase 43 354 4.7E-31 T 29-03-2018 IPR007184 Mannoside phosphorylase SMALA_RS41145 0859d1be8608289648cb8a79b6f9b729 359 Gene3D G3DSA:2.115.10.20 4 357 3.0E-54 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain SMALA_RS31840 c0c2134c4207f01c3c8b4ca376264789 184 Pfam PF03358 NADPH-dependent FMN reductase 4 144 1.8E-30 T 29-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 SMALA_RS31840 c0c2134c4207f01c3c8b4ca376264789 184 TIGRFAM TIGR03567 FMN_reduc_SsuE: FMN reductase 3 171 4.9E-67 T 29-03-2018 IPR020048 NADPH-dependent FMN reductase, SsuE GO:0008752|GO:0046306|GO:0055114 KEGG: 00740+1.5.1.38|MetaCyc: PWY-7723 SMALA_RS31840 c0c2134c4207f01c3c8b4ca376264789 184 SUPERFAMILY SSF52218 3 170 8.07E-34 T 29-03-2018 IPR029039 Flavoprotein-like domain SMALA_RS31840 c0c2134c4207f01c3c8b4ca376264789 184 Gene3D G3DSA:3.40.50.360 2 180 4.3E-36 T 29-03-2018 IPR029039 Flavoprotein-like domain SMALA_RS21535 ebf68cb7c149a268bfa3f3e4069f2a86 370 PRINTS PR00834 HtrA/DegQ protease family signature 295 312 4.2E-27 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMALA_RS21535 ebf68cb7c149a268bfa3f3e4069f2a86 370 PRINTS PR00834 HtrA/DegQ protease family signature 187 207 4.2E-27 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMALA_RS21535 ebf68cb7c149a268bfa3f3e4069f2a86 370 PRINTS PR00834 HtrA/DegQ protease family signature 317 334 4.2E-27 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMALA_RS21535 ebf68cb7c149a268bfa3f3e4069f2a86 370 PRINTS PR00834 HtrA/DegQ protease family signature 166 178 4.2E-27 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMALA_RS21535 ebf68cb7c149a268bfa3f3e4069f2a86 370 Gene3D G3DSA:2.40.10.10 224 360 5.3E-36 T 29-03-2018 SMALA_RS21535 ebf68cb7c149a268bfa3f3e4069f2a86 370 Pfam PF13365 Trypsin-like peptidase domain 157 324 5.3E-31 T 29-03-2018 SMALA_RS21535 ebf68cb7c149a268bfa3f3e4069f2a86 370 Gene3D G3DSA:2.40.10.10 127 223 1.4E-31 T 29-03-2018 SMALA_RS21535 ebf68cb7c149a268bfa3f3e4069f2a86 370 SUPERFAMILY SSF50494 134 260 1.88E-51 T 29-03-2018 IPR009003 Peptidase S1, PA clan SMALA_RS21535 ebf68cb7c149a268bfa3f3e4069f2a86 370 SUPERFAMILY SSF50494 293 365 1.88E-51 T 29-03-2018 IPR009003 Peptidase S1, PA clan SMALA_RS30360 7971b83be045b2769b52db292cca7e80 132 Gene3D G3DSA:2.30.110.10 9 131 2.5E-18 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS30360 7971b83be045b2769b52db292cca7e80 132 SUPERFAMILY SSF50475 4 120 2.81E-19 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS30360 7971b83be045b2769b52db292cca7e80 132 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 14 93 7.2E-11 T 29-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 SMALA_RS30360 7971b83be045b2769b52db292cca7e80 132 TIGRFAM TIGR04023 PPOX_MSMEG_5819: PPOX class F420-dependent enzyme, MSMEG_5819/OxyR family 4 120 9.7E-40 T 29-03-2018 IPR024031 PPOX class F420-dependent enzyme, MSMEG_5819/OxyR family SMALA_RS39755 4fcb208592ed1b710b091dc089c12fff 188 Gene3D G3DSA:1.10.357.10 53 186 1.8E-18 T 29-03-2018 SMALA_RS39755 4fcb208592ed1b710b091dc089c12fff 188 Gene3D G3DSA:1.10.10.60 6 52 2.0E-19 T 29-03-2018 SMALA_RS39755 4fcb208592ed1b710b091dc089c12fff 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 2.5E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS39755 4fcb208592ed1b710b091dc089c12fff 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 2.5E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS39755 4fcb208592ed1b710b091dc089c12fff 188 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 55 1.5E-16 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS39755 4fcb208592ed1b710b091dc089c12fff 188 SUPERFAMILY SSF46689 2 74 4.16E-18 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS08700 e4803cfb9e071dfe547bfc4e02363d8b 388 Pfam PF13614 AAA domain 134 309 9.3E-62 T 29-03-2018 IPR025669 AAA domain SMALA_RS08700 e4803cfb9e071dfe547bfc4e02363d8b 388 SUPERFAMILY SSF52540 133 385 6.6E-65 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS08700 e4803cfb9e071dfe547bfc4e02363d8b 388 Gene3D G3DSA:3.40.50.300 132 387 3.7E-60 T 29-03-2018 SMALA_RS04770 cf9db55999908a82f09e3a7a57f48222 287 Gene3D G3DSA:1.10.260.40 1 89 3.2E-15 T 29-03-2018 SMALA_RS04770 cf9db55999908a82f09e3a7a57f48222 287 SUPERFAMILY SSF47413 32 82 2.25E-9 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS04770 cf9db55999908a82f09e3a7a57f48222 287 SMART SM00530 11 83 6.2E-10 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS04770 cf9db55999908a82f09e3a7a57f48222 287 Pfam PF13560 Helix-turn-helix domain 7 86 5.4E-16 T 29-03-2018 SMALA_RS41300 7c739ddebe2dd947e82fae024c299afc 94 Pfam PF02680 Uncharacterized ArCR, COG1888 3 89 5.4E-31 T 29-03-2018 IPR003831 Protein of unknown function DUF211 SMALA_RS41300 7c739ddebe2dd947e82fae024c299afc 94 Gene3D G3DSA:3.30.70.1340 17 80 2.0E-19 T 29-03-2018 SMALA_RS41300 7c739ddebe2dd947e82fae024c299afc 94 ProDom PD012512 ARCHAEA PH1931 STS176 TA1183 MJ0319 PRECURSOR TVG0378908 UNCHARACTERIZED DUF211 AF1549 12 88 6.0E-17 T 29-03-2018 IPR003831 Protein of unknown function DUF211 SMALA_RS41300 7c739ddebe2dd947e82fae024c299afc 94 SUPERFAMILY SSF160363 1 90 1.31E-27 T 29-03-2018 IPR023129 MTH889-like domain SMALA_RS17260 999a1de2adfab497e0663c7681248847 151 Pfam PF04255 Protein of unknown function (DUF433) 27 75 4.5E-6 T 29-03-2018 IPR007367 Protein of unknown function DUF433 SMALA_RS17260 999a1de2adfab497e0663c7681248847 151 Gene3D G3DSA:1.10.10.10 25 86 1.8E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS05665 52b0d802b0344e6cb38e7c9a76224cae 153 Pfam PF01042 Endoribonuclease L-PSP 38 146 4.7E-21 T 29-03-2018 IPR006175 YjgF/YER057c/UK114 family SMALA_RS05665 52b0d802b0344e6cb38e7c9a76224cae 153 Gene3D G3DSA:3.30.1330.40 32 153 2.4E-28 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SMALA_RS05665 52b0d802b0344e6cb38e7c9a76224cae 153 SUPERFAMILY SSF55298 36 149 1.02E-30 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SMALA_RS22705 a357ec2722223a4a0451ab0d6f9c17e4 159 Gene3D G3DSA:3.30.565.10 30 157 9.5E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS22705 a357ec2722223a4a0451ab0d6f9c17e4 159 SUPERFAMILY SSF55874 52 154 3.51E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS22705 a357ec2722223a4a0451ab0d6f9c17e4 159 Pfam PF13581 Histidine kinase-like ATPase domain 38 153 2.4E-7 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS04485 40927d4bd3d00313ba8a368017ea2627 332 Gene3D G3DSA:3.40.50.1400 209 322 0.0085 T 29-03-2018 SMALA_RS04485 40927d4bd3d00313ba8a368017ea2627 332 Gene3D G3DSA:3.40.50.1400 35 202 1.6E-17 T 29-03-2018 SMALA_RS24465 23edd2447bf653643353929c9a38588a 662 SMART SM00382 37 226 3.6E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS24465 23edd2447bf653643353929c9a38588a 662 SMART SM00382 310 590 3.9E-18 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS24465 23edd2447bf653643353929c9a38588a 662 ProSitePatterns PS00211 ABC transporters family signature. 513 527 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS24465 23edd2447bf653643353929c9a38588a 662 SUPERFAMILY SSF52540 286 346 1.48E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS24465 23edd2447bf653643353929c9a38588a 662 SUPERFAMILY SSF52540 438 608 1.48E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS24465 23edd2447bf653643353929c9a38588a 662 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS24465 23edd2447bf653643353929c9a38588a 662 SUPERFAMILY SSF52540 6 255 1.57E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS24465 23edd2447bf653643353929c9a38588a 662 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 228 262 1.4E-5 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMALA_RS24465 23edd2447bf653643353929c9a38588a 662 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 592 622 7.6E-5 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMALA_RS24465 23edd2447bf653643353929c9a38588a 662 Pfam PF00005 ABC transporter 29 176 3.0E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS24465 23edd2447bf653643353929c9a38588a 662 Pfam PF00005 ABC transporter 447 540 1.3E-11 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS24465 23edd2447bf653643353929c9a38588a 662 Pfam PF00005 ABC transporter 302 342 9.4E-9 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS24465 23edd2447bf653643353929c9a38588a 662 Gene3D G3DSA:3.40.50.300 5 267 1.7E-62 T 29-03-2018 SMALA_RS24465 23edd2447bf653643353929c9a38588a 662 Gene3D G3DSA:3.40.50.300 281 629 7.0E-67 T 29-03-2018 SMALA_RS24565 7f5e8555bd1400eafb93ad01cecb6979 274 SMART SM00530 17 72 5.6E-8 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS24565 7f5e8555bd1400eafb93ad01cecb6979 274 SUPERFAMILY SSF47413 12 69 6.19E-10 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS24565 7f5e8555bd1400eafb93ad01cecb6979 274 Pfam PF13560 Helix-turn-helix domain 15 69 4.9E-12 T 29-03-2018 SMALA_RS24565 7f5e8555bd1400eafb93ad01cecb6979 274 Gene3D G3DSA:1.10.3100.10 9 146 1.2E-14 T 29-03-2018 IPR027910 YdiL-like domain SMALA_RS36945 da0de8eaec4722b15a9512c5c469a024 185 Pfam PF07681 DoxX 32 116 2.6E-13 T 29-03-2018 IPR032808 DoxX family SMALA_RS25865 505afe12f6dc5c6a8ef099e162261c4f 337 SUPERFAMILY SSF103481 232 327 1.44E-8 T 29-03-2018 SMALA_RS25865 505afe12f6dc5c6a8ef099e162261c4f 337 Pfam PF00892 EamA-like transporter family 188 322 1.2E-6 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SMALA_RS25865 505afe12f6dc5c6a8ef099e162261c4f 337 Pfam PF00892 EamA-like transporter family 48 175 8.1E-8 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SMALA_RS25865 505afe12f6dc5c6a8ef099e162261c4f 337 SUPERFAMILY SSF103481 77 177 2.09E-8 T 29-03-2018 SMALA_RS37430 b1b446dd432149b7092c4d4ff33480b2 222 SUPERFAMILY SSF54631 6 149 1.09E-34 T 29-03-2018 SMALA_RS37430 b1b446dd432149b7092c4d4ff33480b2 222 PIRSF PIRSF036990 7 221 2.7E-65 T 29-03-2018 IPR017080 Uncharacterised conserved protein UCP036990, CBS, BON SMALA_RS37430 b1b446dd432149b7092c4d4ff33480b2 222 Gene3D G3DSA:3.10.580.10 82 211 8.2E-21 T 29-03-2018 SMALA_RS37430 b1b446dd432149b7092c4d4ff33480b2 222 Gene3D G3DSA:3.10.580.10 4 81 1.0E-11 T 29-03-2018 SMALA_RS37430 b1b446dd432149b7092c4d4ff33480b2 222 Pfam PF00571 CBS domain 8 59 8.9E-10 T 29-03-2018 IPR000644 CBS domain SMALA_RS37430 b1b446dd432149b7092c4d4ff33480b2 222 Pfam PF00571 CBS domain 90 143 1.1E-17 T 29-03-2018 IPR000644 CBS domain SMALA_RS37430 b1b446dd432149b7092c4d4ff33480b2 222 Pfam PF04972 BON domain 146 210 3.6E-12 T 29-03-2018 IPR007055 BON domain SMALA_RS37430 b1b446dd432149b7092c4d4ff33480b2 222 SMART SM00116 96 144 4.4E-15 T 29-03-2018 IPR000644 CBS domain SMALA_RS37430 b1b446dd432149b7092c4d4ff33480b2 222 SMART SM00116 15 63 1.5 T 29-03-2018 IPR000644 CBS domain SMALA_RS32950 91628e5ff3755552147cd01af0fb3027 409 Pfam PF03993 Domain of Unknown Function (DUF349) 91 164 1.0E-10 T 29-03-2018 IPR007139 Protein of unknown function DUF349 SMALA_RS32950 91628e5ff3755552147cd01af0fb3027 409 Pfam PF03993 Domain of Unknown Function (DUF349) 245 318 4.2E-22 T 29-03-2018 IPR007139 Protein of unknown function DUF349 SMALA_RS32950 91628e5ff3755552147cd01af0fb3027 409 Pfam PF03993 Domain of Unknown Function (DUF349) 168 241 4.6E-21 T 29-03-2018 IPR007139 Protein of unknown function DUF349 SMALA_RS32950 91628e5ff3755552147cd01af0fb3027 409 Gene3D G3DSA:1.20.1170.10 51 407 3.2E-6 T 29-03-2018 SMALA_RS17545 5d5991fe557b795dad9fdf11e8de5371 310 Gene3D G3DSA:3.30.420.40 1 124 6.6E-31 T 29-03-2018 SMALA_RS17545 5d5991fe557b795dad9fdf11e8de5371 310 Gene3D G3DSA:3.30.420.40 125 310 7.5E-51 T 29-03-2018 SMALA_RS17545 5d5991fe557b795dad9fdf11e8de5371 310 SUPERFAMILY SSF53067 3 304 2.92E-54 T 29-03-2018 SMALA_RS17545 5d5991fe557b795dad9fdf11e8de5371 310 Pfam PF00480 ROK family 5 301 2.3E-58 T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 SMALA_RS05520 1f6178f9c21a2cd6541ef8a808332502 173 Pfam PF03061 Thioesterase superfamily 72 149 5.9E-16 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 SMALA_RS05520 1f6178f9c21a2cd6541ef8a808332502 173 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 41 157 6.5E-25 T 29-03-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 SMALA_RS05520 1f6178f9c21a2cd6541ef8a808332502 173 Gene3D G3DSA:3.10.129.10 24 160 3.4E-36 T 29-03-2018 SMALA_RS05520 1f6178f9c21a2cd6541ef8a808332502 173 SUPERFAMILY SSF54637 8 157 3.51E-38 T 29-03-2018 IPR029069 HotDog domain SMALA_RS06350 8364eee323aac57bd8a9037444c16bc5 363 Gene3D G3DSA:3.40.50.1820 56 363 3.0E-45 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS06350 8364eee323aac57bd8a9037444c16bc5 363 Pfam PF00561 alpha/beta hydrolase fold 103 191 2.0E-21 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS06350 8364eee323aac57bd8a9037444c16bc5 363 SUPERFAMILY SSF53474 78 362 2.25E-62 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS06350 8364eee323aac57bd8a9037444c16bc5 363 PRINTS PR00412 Epoxide hydrolase signature 172 185 1.7E-9 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS06350 8364eee323aac57bd8a9037444c16bc5 363 PRINTS PR00412 Epoxide hydrolase signature 338 360 1.7E-9 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS06350 8364eee323aac57bd8a9037444c16bc5 363 PRINTS PR00412 Epoxide hydrolase signature 108 126 1.7E-9 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS34445 3baf996c574ceb50501450127d15edc4 180 SUPERFAMILY SSF55826 36 174 1.57E-19 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 SMALA_RS34445 3baf996c574ceb50501450127d15edc4 180 Gene3D G3DSA:3.90.960.10 18 176 3.5E-20 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 SMALA_RS34445 3baf996c574ceb50501450127d15edc4 180 Pfam PF04073 Aminoacyl-tRNA editing domain 47 159 2.3E-13 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 SMALA_RS05475 5e858e246600a99094be113a8cb55811 154 Pfam PF12680 SnoaL-like domain 5 109 3.5E-10 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain SMALA_RS05475 5e858e246600a99094be113a8cb55811 154 Gene3D G3DSA:3.10.450.50 2 139 8.9E-23 T 29-03-2018 SMALA_RS05475 5e858e246600a99094be113a8cb55811 154 SUPERFAMILY SSF54427 2 116 3.74E-19 T 29-03-2018 IPR032710 NTF2-like domain SMALA_RS14925 0a0b9055852e09aecaa2e4cd016f8f95 286 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 76 282 1.4E-65 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 SMALA_RS14925 0a0b9055852e09aecaa2e4cd016f8f95 286 Gene3D G3DSA:3.90.850.10 23 286 1.7E-78 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 SMALA_RS14925 0a0b9055852e09aecaa2e4cd016f8f95 286 SUPERFAMILY SSF56529 69 284 9.81E-75 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 SMALA_RS02890 996097321e94bd12fc038a8cb325dd35 270 SUPERFAMILY SSF47413 29 79 8.04E-5 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS02890 996097321e94bd12fc038a8cb325dd35 270 Gene3D G3DSA:1.10.260.40 1 83 1.3E-14 T 29-03-2018 SMALA_RS02890 996097321e94bd12fc038a8cb325dd35 270 Pfam PF13560 Helix-turn-helix domain 5 84 3.5E-17 T 29-03-2018 SMALA_RS02890 996097321e94bd12fc038a8cb325dd35 270 SMART SM00530 9 81 6.9E-7 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS23885 e3c5b926e41bcc363b9185e154473a24 938 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 454 847 2.8E-64 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain SMALA_RS23885 e3c5b926e41bcc363b9185e154473a24 938 Gene3D G3DSA:3.40.190.10 560 696 1.3E-22 T 29-03-2018 SMALA_RS23885 e3c5b926e41bcc363b9185e154473a24 938 Gene3D G3DSA:3.10.105.10 697 905 7.7E-34 T 29-03-2018 SMALA_RS23885 e3c5b926e41bcc363b9185e154473a24 938 SUPERFAMILY SSF52129 10 216 1.26E-5 T 29-03-2018 IPR029030 Caspase-like domain SMALA_RS23885 e3c5b926e41bcc363b9185e154473a24 938 Gene3D G3DSA:3.90.76.10 440 559 5.2E-22 T 29-03-2018 SMALA_RS23885 e3c5b926e41bcc363b9185e154473a24 938 Pfam PF00656 Caspase domain 11 149 5.6E-8 T 29-03-2018 SMALA_RS23885 e3c5b926e41bcc363b9185e154473a24 938 SUPERFAMILY SSF53850 404 934 4.16E-87 T 29-03-2018 SMALA_RS23885 e3c5b926e41bcc363b9185e154473a24 938 Gene3D G3DSA:3.40.50.1460 8 234 2.0E-22 T 29-03-2018 SMALA_RS15855 260327e964d85f74c142e649f20b413e 149 Pfam PF12005 Protein of unknown function (DUF3499) 20 145 6.6E-47 T 29-03-2018 IPR021888 Protein of unknown function DUF3499 SMALA_RS39535 1a0a63c5bb2d5078913c23f640986a6f 366 SUPERFAMILY SSF81296 20 121 9.8E-23 T 29-03-2018 IPR014756 Immunoglobulin E-set SMALA_RS39535 1a0a63c5bb2d5078913c23f640986a6f 366 SUPERFAMILY SSF53474 133 358 8.11E-29 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS39535 1a0a63c5bb2d5078913c23f640986a6f 366 Gene3D G3DSA:2.60.40.10 18 124 2.3E-21 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS39535 1a0a63c5bb2d5078913c23f640986a6f 366 Pfam PF00756 Putative esterase 146 363 1.6E-34 T 29-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 SMALA_RS39535 1a0a63c5bb2d5078913c23f640986a6f 366 Gene3D G3DSA:3.40.50.1820 125 366 3.0E-20 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS13150 4b7319e76301d86d94ede01a5fa2e02d 545 Pfam PF05235 CHAD domain 261 493 5.8E-54 T 29-03-2018 IPR007899 CHAD domain SMALA_RS13150 4b7319e76301d86d94ede01a5fa2e02d 545 SUPERFAMILY SSF55154 6 213 5.89E-38 T 29-03-2018 IPR033469 CYTH-like domain Reactome: R-HSA-196819 SMALA_RS13150 4b7319e76301d86d94ede01a5fa2e02d 545 SMART SM00880 261 527 1.0E-66 T 29-03-2018 IPR007899 CHAD domain SMALA_RS13150 4b7319e76301d86d94ede01a5fa2e02d 545 SMART SM01118 5 214 1.7E-14 T 29-03-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 SMALA_RS13150 4b7319e76301d86d94ede01a5fa2e02d 545 Gene3D G3DSA:2.40.320.10 3 220 9.4E-36 T 29-03-2018 SMALA_RS13150 4b7319e76301d86d94ede01a5fa2e02d 545 Pfam PF01928 CYTH domain 37 178 1.1E-11 T 29-03-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 SMALA_RS04735 408217fdb19c5a395ae9ae6e0e8761d1 371 Pfam PF16317 Glycosyl hydrolase family 99 54 366 1.3E-68 T 29-03-2018 IPR026071 Glycosyl hydrolase family 99 GO:0016798 SMALA_RS07485 f36a03b0ad3a56d215e9934d328be911 313 Gene3D G3DSA:3.40.50.150 2 96 8.1E-20 T 29-03-2018 SMALA_RS07485 f36a03b0ad3a56d215e9934d328be911 313 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 30 47 1.2E-8 T 29-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 SMALA_RS07485 f36a03b0ad3a56d215e9934d328be911 313 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 49 67 1.2E-8 T 29-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 SMALA_RS07485 f36a03b0ad3a56d215e9934d328be911 313 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 72 92 1.2E-8 T 29-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 SMALA_RS07485 f36a03b0ad3a56d215e9934d328be911 313 Gene3D G3DSA:3.40.50.150 97 287 4.5E-13 T 29-03-2018 SMALA_RS07485 f36a03b0ad3a56d215e9934d328be911 313 Pfam PF01555 DNA methylase 5 87 4.4E-13 T 29-03-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 SMALA_RS07485 f36a03b0ad3a56d215e9934d328be911 313 SUPERFAMILY SSF53335 25 200 1.25E-24 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS39820 fe243835d2d30e122232a235905f92f5 479 Gene3D G3DSA:3.40.309.10 278 468 4.1E-65 T 29-03-2018 SMALA_RS39820 fe243835d2d30e122232a235905f92f5 479 SUPERFAMILY SSF53720 18 478 9.82E-159 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMALA_RS39820 fe243835d2d30e122232a235905f92f5 479 Gene3D G3DSA:3.40.605.10 18 277 9.6E-97 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS39820 fe243835d2d30e122232a235905f92f5 479 Pfam PF00171 Aldehyde dehydrogenase family 36 478 4.9E-162 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS02505 e45fea4a4b8aef53bbbb9cf065b6a433 169 Gene3D G3DSA:2.30.110.10 1 164 5.8E-23 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS02505 e45fea4a4b8aef53bbbb9cf065b6a433 169 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 29 110 1.9E-12 T 29-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 SMALA_RS02505 e45fea4a4b8aef53bbbb9cf065b6a433 169 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 35 161 2.0E-26 T 29-03-2018 IPR019920 F420-binding domain, putative SMALA_RS02505 e45fea4a4b8aef53bbbb9cf065b6a433 169 SUPERFAMILY SSF50475 29 162 2.24E-26 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS23265 c6183f10760ff2b9cf1a55756db77ef1 297 Pfam PF13560 Helix-turn-helix domain 13 74 5.8E-18 T 29-03-2018 SMALA_RS23265 c6183f10760ff2b9cf1a55756db77ef1 297 SMART SM00530 17 72 2.5E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS23265 c6183f10760ff2b9cf1a55756db77ef1 297 Gene3D G3DSA:1.10.3100.10 9 157 1.8E-20 T 29-03-2018 IPR027910 YdiL-like domain SMALA_RS23265 c6183f10760ff2b9cf1a55756db77ef1 297 SUPERFAMILY SSF47413 10 72 2.65E-13 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS02400 003335d2e30d48e0237525af0b2b8b5b 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 58 2.6E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS02400 003335d2e30d48e0237525af0b2b8b5b 193 Gene3D G3DSA:1.10.357.10 59 191 1.1E-17 T 29-03-2018 SMALA_RS02400 003335d2e30d48e0237525af0b2b8b5b 193 SUPERFAMILY SSF46689 5 77 1.23E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS02400 003335d2e30d48e0237525af0b2b8b5b 193 Gene3D G3DSA:1.10.10.60 1 58 3.7E-18 T 29-03-2018 SMALA_RS02400 003335d2e30d48e0237525af0b2b8b5b 193 ProSitePatterns PS01081 TetR-type HTH domain signature. 29 60 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site SMALA_RS32775 787861b7938bd2e23fe794969f4ce56a 351 PRINTS PR00095 Anthranilate synthase component I signature 284 298 7.3E-11 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 SMALA_RS32775 787861b7938bd2e23fe794969f4ce56a 351 PRINTS PR00095 Anthranilate synthase component I signature 188 201 7.3E-11 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 SMALA_RS32775 787861b7938bd2e23fe794969f4ce56a 351 PRINTS PR00095 Anthranilate synthase component I signature 268 282 7.3E-11 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 SMALA_RS32775 787861b7938bd2e23fe794969f4ce56a 351 Pfam PF00425 chorismate binding enzyme 79 331 2.6E-68 T 29-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal SMALA_RS32775 787861b7938bd2e23fe794969f4ce56a 351 Gene3D G3DSA:3.60.120.10 20 348 1.8E-94 T 29-03-2018 IPR005801 ADC synthase GO:0009058 SMALA_RS32775 787861b7938bd2e23fe794969f4ce56a 351 SUPERFAMILY SSF56322 55 338 3.79E-86 T 29-03-2018 IPR005801 ADC synthase GO:0009058 SMALA_RS21515 d9ec26e7e43ee34f03f7ac76bb8b170a 652 Gene3D G3DSA:3.40.50.300 394 648 1.6E-73 T 29-03-2018 SMALA_RS21515 d9ec26e7e43ee34f03f7ac76bb8b170a 652 SUPERFAMILY SSF52540 401 644 3.15E-88 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS21515 d9ec26e7e43ee34f03f7ac76bb8b170a 652 SMART SM00382 433 619 1.0E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS21515 d9ec26e7e43ee34f03f7ac76bb8b170a 652 Pfam PF00664 ABC transporter transmembrane region 69 362 1.5E-60 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMALA_RS21515 d9ec26e7e43ee34f03f7ac76bb8b170a 652 ProSitePatterns PS00211 ABC transporters family signature. 545 559 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS21515 d9ec26e7e43ee34f03f7ac76bb8b170a 652 SUPERFAMILY SSF90123 37 76 1.7E-85 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMALA_RS21515 d9ec26e7e43ee34f03f7ac76bb8b170a 652 SUPERFAMILY SSF90123 116 395 1.7E-85 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMALA_RS21515 d9ec26e7e43ee34f03f7ac76bb8b170a 652 Pfam PF00005 ABC transporter 425 573 2.2E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS21515 d9ec26e7e43ee34f03f7ac76bb8b170a 652 Gene3D G3DSA:1.20.1560.10 24 393 1.0E-89 T 29-03-2018 SMALA_RS36320 d441ac53674f1f01a10f5abdfee12d13 333 Gene3D G3DSA:1.20.58.370 23 68 4.4E-4 T 29-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain SMALA_RS36320 d441ac53674f1f01a10f5abdfee12d13 333 Gene3D G3DSA:1.10.3720.10 96 330 7.0E-43 T 29-03-2018 SMALA_RS36320 d441ac53674f1f01a10f5abdfee12d13 333 SUPERFAMILY SSF161098 85 317 2.75E-53 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS36320 d441ac53674f1f01a10f5abdfee12d13 333 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 124 328 1.4E-19 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS08615 cfd1485d46ec5dfae659a6ca503c5acb 67 Pfam PF00741 Gas vesicle protein 16 54 2.3E-14 T 29-03-2018 IPR000638 Gas vesicle protein GvpA GO:0005198|GO:0012506 SMALA_RS14975 ff469a1b58c285430b8f4cef3bada597 781 Pfam PF00905 Penicillin binding protein transpeptidase domain 384 639 6.8E-30 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 SMALA_RS14975 ff469a1b58c285430b8f4cef3bada597 781 Gene3D G3DSA:3.40.710.10 301 706 4.6E-94 T 29-03-2018 SMALA_RS14975 ff469a1b58c285430b8f4cef3bada597 781 Gene3D G3DSA:1.10.3810.10 99 298 6.0E-70 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 SMALA_RS14975 ff469a1b58c285430b8f4cef3bada597 781 SUPERFAMILY SSF53955 97 297 2.53E-63 T 29-03-2018 IPR023346 Lysozyme-like domain SMALA_RS14975 ff469a1b58c285430b8f4cef3bada597 781 SUPERFAMILY SSF56601 315 683 2.93E-84 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMALA_RS14975 ff469a1b58c285430b8f4cef3bada597 781 SUPERFAMILY SSF56601 267 286 2.93E-84 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMALA_RS14975 ff469a1b58c285430b8f4cef3bada597 781 Pfam PF00912 Transglycosylase 111 282 9.5E-59 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 SMALA_RS33340 c93e49c8395e7d192ac5ba84ecea986c 209 Gene3D G3DSA:3.40.50.300 9 173 5.7E-16 T 29-03-2018 SMALA_RS33340 c93e49c8395e7d192ac5ba84ecea986c 209 SUPERFAMILY SSF52540 21 164 7.86E-17 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS04225 803527b8458a92606eaeb527e02a4671 238 Gene3D G3DSA:3.90.226.10 1 236 9.4E-64 T 29-03-2018 SMALA_RS04225 803527b8458a92606eaeb527e02a4671 238 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 225 2.0E-48 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 SMALA_RS04225 803527b8458a92606eaeb527e02a4671 238 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 99 119 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 SMALA_RS04225 803527b8458a92606eaeb527e02a4671 238 SUPERFAMILY SSF52096 2 232 2.49E-65 T 29-03-2018 IPR029045 ClpP/crotonase-like domain SMALA_RS33110 7ad9aadb5cec015e2f69fceec60bb3c5 369 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 300 320 - T 29-03-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 SMALA_RS33110 7ad9aadb5cec015e2f69fceec60bb3c5 369 SUPERFAMILY SSF51395 1 362 3.97E-101 T 29-03-2018 SMALA_RS33110 7ad9aadb5cec015e2f69fceec60bb3c5 369 TIGRFAM TIGR01036 pyrD_sub2: dihydroorotate dehydrogenase (fumarate) 4 363 5.6E-127 T 29-03-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 SMALA_RS33110 7ad9aadb5cec015e2f69fceec60bb3c5 369 Hamap MF_00225 Dihydroorotate dehydrogenase (quinone) [pyrD]. 1 344 46.858 T 29-03-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 SMALA_RS33110 7ad9aadb5cec015e2f69fceec60bb3c5 369 Gene3D G3DSA:3.20.20.70 1 369 7.8E-85 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS33110 7ad9aadb5cec015e2f69fceec60bb3c5 369 Pfam PF01180 Dihydroorotate dehydrogenase 50 348 5.9E-94 T 29-03-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 SMALA_RS01135 64f2ce31b46569f12098b45d5b8927b0 434 SUPERFAMILY SSF51905 1 174 4.76E-50 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS01135 64f2ce31b46569f12098b45d5b8927b0 434 SUPERFAMILY SSF51905 280 403 4.76E-50 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS01135 64f2ce31b46569f12098b45d5b8927b0 434 Pfam PF01494 FAD binding domain 4 351 6.7E-28 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 SMALA_RS01135 64f2ce31b46569f12098b45d5b8927b0 434 Gene3D G3DSA:3.50.50.60 2 361 3.7E-39 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS01135 64f2ce31b46569f12098b45d5b8927b0 434 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 284 299 7.8E-14 T 29-03-2018 SMALA_RS01135 64f2ce31b46569f12098b45d5b8927b0 434 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 7.8E-14 T 29-03-2018 SMALA_RS01135 64f2ce31b46569f12098b45d5b8927b0 434 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 299 315 7.8E-14 T 29-03-2018 SMALA_RS01135 64f2ce31b46569f12098b45d5b8927b0 434 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 153 168 7.8E-14 T 29-03-2018 SMALA_RS12085 0484974953df10b90a66874f06f32747 387 SUPERFAMILY SSF54826 2 113 1.85E-27 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMALA_RS12085 0484974953df10b90a66874f06f32747 387 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 17 111 1.9E-17 T 29-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain SMALA_RS12085 0484974953df10b90a66874f06f32747 387 SMART SM00922 132 237 3.3E-24 T 29-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal SMALA_RS12085 0484974953df10b90a66874f06f32747 387 Gene3D G3DSA:3.20.20.120 114 369 6.8E-68 T 29-03-2018 IPR029065 Enolase C-terminal domain-like SMALA_RS12085 0484974953df10b90a66874f06f32747 387 Pfam PF13378 Enolase C-terminal domain-like 138 357 7.2E-63 T 29-03-2018 IPR029065 Enolase C-terminal domain-like SMALA_RS12085 0484974953df10b90a66874f06f32747 387 SUPERFAMILY SSF51604 99 364 3.67E-79 T 29-03-2018 IPR029065 Enolase C-terminal domain-like SMALA_RS12085 0484974953df10b90a66874f06f32747 387 Gene3D G3DSA:3.30.390.10 1 113 1.2E-31 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMALA_RS39600 b78754302846c366ddb8ef229b880fb1 187 SUPERFAMILY SSF46689 6 86 3.99E-19 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS39600 b78754302846c366ddb8ef229b880fb1 187 Gene3D G3DSA:1.10.260.40 41 69 8.4E-13 T 29-03-2018 SMALA_RS39600 b78754302846c366ddb8ef229b880fb1 187 Gene3D G3DSA:1.10.357.10 70 187 8.2E-13 T 29-03-2018 SMALA_RS39600 b78754302846c366ddb8ef229b880fb1 187 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 2.9E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS39600 b78754302846c366ddb8ef229b880fb1 187 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 2.9E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS39600 b78754302846c366ddb8ef229b880fb1 187 SUPERFAMILY SSF48498 83 185 3.76E-12 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS39600 b78754302846c366ddb8ef229b880fb1 187 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 64 9.3E-16 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS39600 b78754302846c366ddb8ef229b880fb1 187 Gene3D G3DSA:1.10.10.60 1 40 5.0E-16 T 29-03-2018 SMALA_RS42590 9fff76ad82c3492b0589e3f75e5bb0df 217 SUPERFAMILY SSF52266 2 190 1.63E-34 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain SMALA_RS42590 9fff76ad82c3492b0589e3f75e5bb0df 217 Gene3D G3DSA:3.40.50.1110 2 192 2.4E-25 T 29-03-2018 SMALA_RS42590 9fff76ad82c3492b0589e3f75e5bb0df 217 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 9 182 7.7E-22 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain SMALA_RS29805 7e26ccace34484046cba81450b54b438 490 Pfam PF13520 Amino acid permease 24 453 5.2E-52 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMALA_RS29805 7e26ccace34484046cba81450b54b438 490 PIRSF PIRSF006060 2 487 7.4E-90 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMALA_RS39845 32985423bee5d9781e2f268d9ac6bc31 309 Gene3D G3DSA:3.40.50.300 1 261 2.5E-55 T 29-03-2018 SMALA_RS39845 32985423bee5d9781e2f268d9ac6bc31 309 SMART SM00382 26 204 1.8E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS39845 32985423bee5d9781e2f268d9ac6bc31 309 Pfam PF00005 ABC transporter 18 156 1.8E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS39845 32985423bee5d9781e2f268d9ac6bc31 309 SUPERFAMILY SSF52540 2 226 1.2E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS13530 7997b990c124125447fb1be1ad2fa1b0 641 SUPERFAMILY SSF52540 147 349 5.53E-23 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS13530 7997b990c124125447fb1be1ad2fa1b0 641 Gene3D G3DSA:3.40.50.300 130 360 8.3E-26 T 29-03-2018 SMALA_RS13530 7997b990c124125447fb1be1ad2fa1b0 641 Pfam PF01926 50S ribosome-binding GTPase 155 268 1.3E-6 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 SMALA_RS30740 903bc37796aab23d3033ee5df4366200 467 Gene3D G3DSA:1.20.1250.20 13 209 1.3E-25 T 29-03-2018 SMALA_RS30740 903bc37796aab23d3033ee5df4366200 467 Gene3D G3DSA:1.20.1250.20 269 457 2.6E-15 T 29-03-2018 SMALA_RS30740 903bc37796aab23d3033ee5df4366200 467 Pfam PF07690 Major Facilitator Superfamily 23 420 2.6E-39 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS30740 903bc37796aab23d3033ee5df4366200 467 SUPERFAMILY SSF103473 262 455 3.14E-49 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS30740 903bc37796aab23d3033ee5df4366200 467 SUPERFAMILY SSF103473 13 205 3.14E-49 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS18220 242c1c13fb935e97f95859c73db92429 562 SUPERFAMILY SSF56672 161 561 8.12E-67 T 29-03-2018 SMALA_RS18220 242c1c13fb935e97f95859c73db92429 562 Pfam PF00476 DNA polymerase family A 247 536 1.0E-28 T 29-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMALA_RS18220 242c1c13fb935e97f95859c73db92429 562 Gene3D G3DSA:3.30.70.370 293 379 1.4E-11 T 29-03-2018 SMALA_RS18220 242c1c13fb935e97f95859c73db92429 562 Gene3D G3DSA:3.30.70.370 380 562 3.7E-24 T 29-03-2018 SMALA_RS18220 242c1c13fb935e97f95859c73db92429 562 SMART SM00482 316 521 3.5E-12 T 29-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMALA_RS18220 242c1c13fb935e97f95859c73db92429 562 PRINTS PR00868 DNA-polymerase family A (pol I) signature 360 373 4.4E-8 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMALA_RS18220 242c1c13fb935e97f95859c73db92429 562 PRINTS PR00868 DNA-polymerase family A (pol I) signature 504 517 4.4E-8 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMALA_RS18220 242c1c13fb935e97f95859c73db92429 562 PRINTS PR00868 DNA-polymerase family A (pol I) signature 330 353 4.4E-8 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMALA_RS18220 242c1c13fb935e97f95859c73db92429 562 PRINTS PR00868 DNA-polymerase family A (pol I) signature 474 490 4.4E-8 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMALA_RS08870 3bcafa81b1baf71807d05f153b6b429b 79 Pfam PF03777 Small secreted domain (DUF320) 25 77 2.1E-20 T 29-03-2018 IPR005528 Domain of unknown function DUF320, Streptomyces species SMALA_RS11815 f0a06d9ec58d88a910ec36b559aeafa1 283 Gene3D G3DSA:1.10.260.40 1 84 1.2E-13 T 29-03-2018 SMALA_RS11815 f0a06d9ec58d88a910ec36b559aeafa1 283 SMART SM00530 9 81 2.3E-5 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS11815 f0a06d9ec58d88a910ec36b559aeafa1 283 Pfam PF13560 Helix-turn-helix domain 5 84 3.3E-16 T 29-03-2018 SMALA_RS11815 f0a06d9ec58d88a910ec36b559aeafa1 283 SUPERFAMILY SSF47413 29 78 3.27E-5 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS31325 f50988edb24c865551c60f7af007bf3d 463 Pfam PF07690 Major Facilitator Superfamily 40 392 1.5E-34 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS31325 f50988edb24c865551c60f7af007bf3d 463 Gene3D G3DSA:1.20.1250.20 234 443 1.8E-20 T 29-03-2018 SMALA_RS31325 f50988edb24c865551c60f7af007bf3d 463 SUPERFAMILY SSF103473 18 439 1.44E-49 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS31325 f50988edb24c865551c60f7af007bf3d 463 Gene3D G3DSA:1.20.1250.20 20 219 5.7E-19 T 29-03-2018 SMALA_RS39440 f322a907ceed85d982d4d5725ae8dd92 428 ProSitePatterns PS00570 Bacterial ring hydroxylating dioxygenases alpha-subunit signature. 70 92 - T 29-03-2018 IPR015881 Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site GO:0005506|GO:0016705|GO:0051537|GO:0055114 SMALA_RS39440 f322a907ceed85d982d4d5725ae8dd92 428 Gene3D G3DSA:3.90.380.10 131 385 2.1E-44 T 29-03-2018 SMALA_RS39440 f322a907ceed85d982d4d5725ae8dd92 428 Pfam PF00355 Rieske [2Fe-2S] domain 27 110 8.3E-17 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMALA_RS39440 f322a907ceed85d982d4d5725ae8dd92 428 Gene3D G3DSA:2.102.10.10 24 130 3.2E-22 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMALA_RS39440 f322a907ceed85d982d4d5725ae8dd92 428 SUPERFAMILY SSF55961 330 384 3.3E-34 T 29-03-2018 SMALA_RS39440 f322a907ceed85d982d4d5725ae8dd92 428 SUPERFAMILY SSF55961 130 299 3.3E-34 T 29-03-2018 SMALA_RS39440 f322a907ceed85d982d4d5725ae8dd92 428 SUPERFAMILY SSF50022 19 138 2.36E-31 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMALA_RS13500 98df41962cd81fc7a360fb6d3efcf35d 134 Gene3D G3DSA:1.10.490.10 9 134 1.5E-36 T 29-03-2018 SMALA_RS13500 98df41962cd81fc7a360fb6d3efcf35d 134 SUPERFAMILY SSF46458 12 132 7.81E-38 T 29-03-2018 IPR009050 Globin-like SMALA_RS13500 98df41962cd81fc7a360fb6d3efcf35d 134 Pfam PF01152 Bacterial-like globin 13 129 4.8E-35 T 29-03-2018 IPR001486 Truncated hemoglobin GO:0019825 SMALA_RS11890 a03bffa85f3721a3697a335b54cf8ffc 286 Gene3D G3DSA:3.40.50.1000 3 269 9.4E-10 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS11890 a03bffa85f3721a3697a335b54cf8ffc 286 SUPERFAMILY SSF56784 41 227 4.27E-14 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS11890 a03bffa85f3721a3697a335b54cf8ffc 286 SUPERFAMILY SSF56784 3 14 4.27E-14 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS11890 a03bffa85f3721a3697a335b54cf8ffc 286 PIRSF PIRSF030802 1 242 2.0E-16 T 29-03-2018 IPR024197 Uncharacterised conserved protein UCP030802 SMALA_RS30830 d7c59ed005ae529a24740c9655103b1e 250 Gene3D G3DSA:3.40.50.1220 6 248 5.7E-61 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain SMALA_RS30830 d7c59ed005ae529a24740c9655103b1e 250 SUPERFAMILY SSF52467 11 244 2.62E-72 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain SMALA_RS30830 d7c59ed005ae529a24740c9655103b1e 250 Pfam PF02146 Sir2 family 16 196 4.1E-46 T 29-03-2018 IPR003000 Sirtuin family GO:0070403 SMALA_RS42295 6820915032e187e5871ff8b50fd3f42d 566 ProSitePatterns PS00455 Putative AMP-binding domain signature. 98 109 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS42295 6820915032e187e5871ff8b50fd3f42d 566 Pfam PF03321 GH3 auxin-responsive promoter 23 542 8.7E-104 T 29-03-2018 IPR004993 GH3 family Reactome: R-HSA-6798695 SMALA_RS30480 b4511d5da301067cb75218a11e360953 390 SUPERFAMILY SSF144083 325 387 9.15E-19 T 29-03-2018 SMALA_RS30480 b4511d5da301067cb75218a11e360953 390 Gene3D G3DSA:3.30.460.20 30 188 9.1E-36 T 29-03-2018 SMALA_RS30480 b4511d5da301067cb75218a11e360953 390 Pfam PF01544 CorA-like Mg2+ transporter protein 85 386 3.4E-63 T 29-03-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 SMALA_RS30480 b4511d5da301067cb75218a11e360953 390 Gene3D G3DSA:1.20.58.340 192 308 7.2E-30 T 29-03-2018 SMALA_RS30480 b4511d5da301067cb75218a11e360953 390 SUPERFAMILY SSF143865 48 307 1.44E-64 T 29-03-2018 SMALA_RS30480 b4511d5da301067cb75218a11e360953 390 Gene3D G3DSA:1.20.58.340 309 390 9.7E-17 T 29-03-2018 SMALA_RS01055 32f9fa1e14f78f032aa415fed2c37a6d 217 SUPERFAMILY SSF46689 5 70 3.98E-10 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS01055 32f9fa1e14f78f032aa415fed2c37a6d 217 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 58 1.1E-4 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS01055 32f9fa1e14f78f032aa415fed2c37a6d 217 Gene3D G3DSA:1.10.357.10 81 213 1.5E-13 T 29-03-2018 SMALA_RS01055 32f9fa1e14f78f032aa415fed2c37a6d 217 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 76 186 4.6E-6 T 29-03-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 SMALA_RS01055 32f9fa1e14f78f032aa415fed2c37a6d 217 Gene3D G3DSA:1.10.260.40 38 80 1.1E-6 T 29-03-2018 SMALA_RS01055 32f9fa1e14f78f032aa415fed2c37a6d 217 Gene3D G3DSA:1.10.10.60 1 37 7.2E-10 T 29-03-2018 SMALA_RS01055 32f9fa1e14f78f032aa415fed2c37a6d 217 SUPERFAMILY SSF48498 78 207 1.33E-11 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS13610 6c6a24751cb12a248c5a82adba2059ab 168 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 37 146 2.0E-21 T 29-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 SMALA_RS13610 6c6a24751cb12a248c5a82adba2059ab 168 TIGRFAM TIGR00494 crcB: protein CrcB 38 148 5.7E-25 T 29-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 SMALA_RS13610 6c6a24751cb12a248c5a82adba2059ab 168 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 35 152 17.866 T 29-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 SMALA_RS29555 60f713e4a29f271dc5c3be6ca06b23cd 425 TIGRFAM TIGR01426 MGT: glycosyltransferase, MGT family 31 417 9.7E-109 T 29-03-2018 IPR006326 UDP-glycosyltransferase, MGT GO:0016758|GO:0016999 SMALA_RS29555 60f713e4a29f271dc5c3be6ca06b23cd 425 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 250 388 1.9E-18 T 29-03-2018 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 Reactome: R-HSA-156588 SMALA_RS29555 60f713e4a29f271dc5c3be6ca06b23cd 425 Gene3D G3DSA:3.40.50.2000 26 255 1.8E-29 T 29-03-2018 SMALA_RS29555 60f713e4a29f271dc5c3be6ca06b23cd 425 Gene3D G3DSA:3.40.50.2000 256 403 4.7E-39 T 29-03-2018 SMALA_RS29555 60f713e4a29f271dc5c3be6ca06b23cd 425 SUPERFAMILY SSF53756 27 418 1.23E-75 T 29-03-2018 SMALA_RS41630 0084a82e9e7871528793bf057b0ca635 297 Gene3D G3DSA:3.40.50.1820 9 296 6.8E-26 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS41630 0084a82e9e7871528793bf057b0ca635 297 SUPERFAMILY SSF53474 13 295 3.59E-24 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS10590 cc95a2310fabeff3d2127cea92a59bac 117 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 99 116 - T 29-03-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 SMALA_RS10590 cc95a2310fabeff3d2127cea92a59bac 117 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 13 117 2.9E-36 T 29-03-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 SMALA_RS10590 cc95a2310fabeff3d2127cea92a59bac 117 Gene3D G3DSA:2.60.300.12 13 117 5.9E-33 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 SMALA_RS10590 cc95a2310fabeff3d2127cea92a59bac 117 Pfam PF01521 Iron-sulphur cluster biosynthesis 13 114 1.6E-19 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 SMALA_RS10590 cc95a2310fabeff3d2127cea92a59bac 117 SUPERFAMILY SSF89360 13 107 1.28E-27 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 SMALA_RS10550 14e641097ff7c9c25611c8e748a3058b 132 Pfam PF12270 Cytochrome c oxidase subunit IV 2 129 2.2E-53 T 29-03-2018 IPR021050 Cytochrome c oxidase subunit IV, actinobacteria GO:0004129|GO:0016021|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 SMALA_RS10550 14e641097ff7c9c25611c8e748a3058b 132 PIRSF PIRSF017385 1 131 3.7E-51 T 29-03-2018 IPR021050 Cytochrome c oxidase subunit IV, actinobacteria GO:0004129|GO:0016021|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 SMALA_RS09145 971847c00cee7a50d5c563ab3455e1ec 532 SUPERFAMILY SSF52540 2 79 4.96E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS09145 971847c00cee7a50d5c563ab3455e1ec 532 SUPERFAMILY SSF52540 128 234 4.96E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS09145 971847c00cee7a50d5c563ab3455e1ec 532 Gene3D G3DSA:3.40.50.300 291 528 8.1E-49 T 29-03-2018 SMALA_RS09145 971847c00cee7a50d5c563ab3455e1ec 532 Gene3D G3DSA:3.40.50.300 1 290 6.6E-50 T 29-03-2018 SMALA_RS09145 971847c00cee7a50d5c563ab3455e1ec 532 SMART SM00382 26 232 2.2E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS09145 971847c00cee7a50d5c563ab3455e1ec 532 SMART SM00382 350 515 1.3E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS09145 971847c00cee7a50d5c563ab3455e1ec 532 Pfam PF12848 ABC transporter 231 302 1.7E-6 T 29-03-2018 IPR032781 ABC-transporter extension domain SMALA_RS09145 971847c00cee7a50d5c563ab3455e1ec 532 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS09145 971847c00cee7a50d5c563ab3455e1ec 532 ProSitePatterns PS00211 ABC transporters family signature. 443 457 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS09145 971847c00cee7a50d5c563ab3455e1ec 532 Pfam PF00005 ABC transporter 19 187 2.9E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS09145 971847c00cee7a50d5c563ab3455e1ec 532 Pfam PF00005 ABC transporter 342 471 6.4E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS09145 971847c00cee7a50d5c563ab3455e1ec 532 SUPERFAMILY SSF52540 330 517 1.5E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS23995 f62508ddc0804c6e9d10619eeb194b48 325 SUPERFAMILY SSF51735 7 319 2.94E-86 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS23995 f62508ddc0804c6e9d10619eeb194b48 325 Gene3D G3DSA:3.90.25.10 173 325 4.5E-39 T 29-03-2018 SMALA_RS23995 f62508ddc0804c6e9d10619eeb194b48 325 Gene3D G3DSA:3.40.50.720 7 172 1.0E-30 T 29-03-2018 SMALA_RS23995 f62508ddc0804c6e9d10619eeb194b48 325 Pfam PF01370 NAD dependent epimerase/dehydratase family 10 248 5.9E-55 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 SMALA_RS23995 f62508ddc0804c6e9d10619eeb194b48 325 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 9 323 1.9E-112 T 29-03-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-70370 SMALA_RS35890 fa8b35697c90baf1d3c707d31af3f09d 222 SUPERFAMILY SSF63965 10 219 1.22E-70 T 29-03-2018 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 SMALA_RS35890 fa8b35697c90baf1d3c707d31af3f09d 222 Gene3D G3DSA:3.40.50.10230 10 222 2.1E-77 T 29-03-2018 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 SMALA_RS35890 fa8b35697c90baf1d3c707d31af3f09d 222 Pfam PF02570 Precorrin-8X methylmutase 19 219 2.1E-70 T 29-03-2018 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 SMALA_RS42060 fc58ab7d225f1f8cbe81507490fdb2ec 1080 SUPERFAMILY SSF52777 204 448 2.22E-35 T 29-03-2018 SMALA_RS42060 fc58ab7d225f1f8cbe81507490fdb2ec 1080 Pfam PF00668 Condensation domain 16 448 5.8E-48 T 29-03-2018 IPR001242 Condensation domain SMALA_RS42060 fc58ab7d225f1f8cbe81507490fdb2ec 1080 Gene3D G3DSA:3.30.559.10 3 207 1.1E-20 T 29-03-2018 SMALA_RS42060 fc58ab7d225f1f8cbe81507490fdb2ec 1080 Gene3D G3DSA:1.10.1200.10 1000 1069 1.5E-18 T 29-03-2018 SMALA_RS42060 fc58ab7d225f1f8cbe81507490fdb2ec 1080 Gene3D G3DSA:2.30.38.10 786 867 4.7E-19 T 29-03-2018 SMALA_RS42060 fc58ab7d225f1f8cbe81507490fdb2ec 1080 ProSitePatterns PS00455 Putative AMP-binding domain signature. 616 627 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS42060 fc58ab7d225f1f8cbe81507490fdb2ec 1080 Pfam PF00501 AMP-binding enzyme 484 877 3.7E-75 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS42060 fc58ab7d225f1f8cbe81507490fdb2ec 1080 SUPERFAMILY SSF56801 476 1004 4.45E-121 T 29-03-2018 SMALA_RS42060 fc58ab7d225f1f8cbe81507490fdb2ec 1080 SUPERFAMILY SSF52777 15 177 1.56E-22 T 29-03-2018 SMALA_RS42060 fc58ab7d225f1f8cbe81507490fdb2ec 1080 Gene3D G3DSA:3.40.50.980 620 777 9.5E-35 T 29-03-2018 SMALA_RS42060 fc58ab7d225f1f8cbe81507490fdb2ec 1080 Gene3D G3DSA:3.30.300.30 872 999 1.8E-25 T 29-03-2018 SMALA_RS42060 fc58ab7d225f1f8cbe81507490fdb2ec 1080 SMART SM00823 Phosphopantetheine attachment site 992 1061 0.0022 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS42060 fc58ab7d225f1f8cbe81507490fdb2ec 1080 Gene3D G3DSA:3.40.50.980 476 619 4.5E-34 T 29-03-2018 SMALA_RS42060 fc58ab7d225f1f8cbe81507490fdb2ec 1080 Pfam PF00550 Phosphopantetheine attachment site 995 1057 2.2E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS42060 fc58ab7d225f1f8cbe81507490fdb2ec 1080 SUPERFAMILY SSF47336 989 1065 7.85E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS42060 fc58ab7d225f1f8cbe81507490fdb2ec 1080 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 504 900 5.1E-102 T 29-03-2018 IPR010071 Amino acid adenylation domain SMALA_RS12825 1828eb9ea031421c01c46914524131e7 157 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 30 80 1.4E-21 T 29-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SMALA_RS12825 1828eb9ea031421c01c46914524131e7 157 SUPERFAMILY SSF69118 16 152 1.14E-38 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 SMALA_RS12825 1828eb9ea031421c01c46914524131e7 157 Pfam PF02627 Carboxymuconolactone decarboxylase family 21 95 4.3E-22 T 29-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SMALA_RS12825 1828eb9ea031421c01c46914524131e7 157 Gene3D G3DSA:1.20.1290.10 1 155 2.5E-36 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 SMALA_RS33115 da277fc81935b8f73bea755145b2c6e8 283 Hamap MF_01215 Orotidine 5'-phosphate decarboxylase [pyrF]. 3 280 33.678 T 29-03-2018 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SMALA_RS33115 da277fc81935b8f73bea755145b2c6e8 283 Gene3D G3DSA:3.20.20.70 4 282 1.4E-83 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS33115 da277fc81935b8f73bea755145b2c6e8 283 TIGRFAM TIGR02127 pyrF_sub2: orotidine 5'-phosphate decarboxylase 5 270 2.8E-83 T 29-03-2018 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SMALA_RS33115 da277fc81935b8f73bea755145b2c6e8 283 SMART SM00934 18 270 2.7E-26 T 29-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 SMALA_RS33115 da277fc81935b8f73bea755145b2c6e8 283 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 18 265 1.0E-34 T 29-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 SMALA_RS33115 da277fc81935b8f73bea755145b2c6e8 283 SUPERFAMILY SSF51366 5 275 1.51E-62 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 SMALA_RS33115 da277fc81935b8f73bea755145b2c6e8 283 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 92 105 - T 29-03-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 SMALA_RS15685 c269e107a6d4aa28f451884eb7b4748c 225 Gene3D G3DSA:3.40.50.2300 2 120 4.4E-37 T 29-03-2018 SMALA_RS15685 c269e107a6d4aa28f451884eb7b4748c 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 221 1.8E-25 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS15685 c269e107a6d4aa28f451884eb7b4748c 225 SMART SM00862 146 222 3.3E-22 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS15685 c269e107a6d4aa28f451884eb7b4748c 225 Pfam PF00072 Response regulator receiver domain 5 114 7.4E-29 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS15685 c269e107a6d4aa28f451884eb7b4748c 225 SUPERFAMILY SSF52172 4 177 1.99E-43 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS15685 c269e107a6d4aa28f451884eb7b4748c 225 SMART SM00448 3 113 5.6E-45 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS15685 c269e107a6d4aa28f451884eb7b4748c 225 Gene3D G3DSA:1.10.10.10 121 224 2.0E-34 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS29165 8712da054bbd5697089b2a9b75046f19 441 Gene3D G3DSA:3.40.462.10 188 406 9.7E-45 T 29-03-2018 IPR016170 Vanillyl-alcohol oxidase/Cytokinin dehydrogenase C-terminal domain SMALA_RS29165 8712da054bbd5697089b2a9b75046f19 441 PIRSF PIRSF000136 3 441 8.8E-117 T 29-03-2018 IPR010031 L-gulonolactone/D-arabinono-1,4-lactone oxidase GO:0016899|GO:0055114 SMALA_RS29165 8712da054bbd5697089b2a9b75046f19 441 Pfam PF04030 D-arabinono-1,4-lactone oxidase 184 438 2.6E-79 T 29-03-2018 IPR007173 D-arabinono-1,4-lactone oxidase GO:0003885|GO:0016020|GO:0055114 SMALA_RS29165 8712da054bbd5697089b2a9b75046f19 441 ProSitePatterns PS00862 Oxygen oxidoreductases covalent FAD-binding site. 25 58 - T 29-03-2018 IPR006093 Oxygen oxidoreductase covalent FAD-binding site GO:0016491|GO:0055114 SMALA_RS29165 8712da054bbd5697089b2a9b75046f19 441 Gene3D G3DSA:3.30.43.10 5 73 8.3E-19 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 SMALA_RS29165 8712da054bbd5697089b2a9b75046f19 441 Gene3D G3DSA:3.30.465.10 74 187 1.2E-28 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SMALA_RS29165 8712da054bbd5697089b2a9b75046f19 441 SUPERFAMILY SSF56176 12 190 1.34E-48 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SMALA_RS29165 8712da054bbd5697089b2a9b75046f19 441 Pfam PF01565 FAD binding domain 25 160 3.7E-33 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 SMALA_RS29165 8712da054bbd5697089b2a9b75046f19 441 TIGRFAM TIGR01679 bact_FAD_ox: FAD-linked oxidoreductase 14 440 2.5E-125 T 29-03-2018 SMALA_RS22270 056f482562aca5e68d7df11d4e601850 235 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 75 184 1.2E-23 T 29-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS22270 056f482562aca5e68d7df11d4e601850 235 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 20 189 40.109 T 29-03-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS22270 056f482562aca5e68d7df11d4e601850 235 SUPERFAMILY SSF56770 54 193 5.1E-61 T 29-03-2018 SMALA_RS22270 056f482562aca5e68d7df11d4e601850 235 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 54 190 6.8E-66 T 29-03-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS22270 056f482562aca5e68d7df11d4e601850 235 Gene3D G3DSA:3.40.50.700 44 202 2.3E-42 T 29-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS04215 5f436e80e33d8b8101b1c885c2a5cd3c 161 Gene3D G3DSA:1.10.10.10 10 157 4.8E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS04215 5f436e80e33d8b8101b1c885c2a5cd3c 161 Pfam PF12802 MarR family 41 98 1.3E-11 T 29-03-2018 SMALA_RS04215 5f436e80e33d8b8101b1c885c2a5cd3c 161 SUPERFAMILY SSF46785 11 145 6.36E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS04215 5f436e80e33d8b8101b1c885c2a5cd3c 161 SMART SM00347 35 133 2.8E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS04550 aa1bfd1b8b8f6c8c5b89da421be8f190 172 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 31 168 1.2E-15 T 29-03-2018 IPR004302 Cellulose/chitin-binding protein, N-terminal SMALA_RS04550 aa1bfd1b8b8f6c8c5b89da421be8f190 172 Gene3D G3DSA:2.70.50.50 31 171 4.5E-32 T 29-03-2018 SMALA_RS04550 aa1bfd1b8b8f6c8c5b89da421be8f190 172 SUPERFAMILY SSF81296 31 171 5.74E-35 T 29-03-2018 IPR014756 Immunoglobulin E-set SMALA_RS09015 a6ea569351eca52a20c280c29ed468ec 129 Pfam PF11298 Protein of unknown function (DUF3099) 11 79 2.8E-23 T 29-03-2018 IPR021449 Protein of unknown function DUF3099 SMALA_RS10395 4d2ba8cf1b426ceafb6a458891f181c7 449 Pfam PF01474 Class-II DAHP synthetase family 12 443 6.3E-201 T 29-03-2018 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 SMALA_RS10395 4d2ba8cf1b426ceafb6a458891f181c7 449 TIGRFAM TIGR01358 DAHP_synth_II: 3-deoxy-7-phosphoheptulonate synthase 11 449 1.9E-232 T 29-03-2018 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 SMALA_RS10395 4d2ba8cf1b426ceafb6a458891f181c7 449 SUPERFAMILY SSF51569 10 447 1.9E-198 T 29-03-2018 SMALA_RS10395 4d2ba8cf1b426ceafb6a458891f181c7 449 Gene3D G3DSA:3.20.20.70 231 395 1.5E-9 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS34255 68d24985c58deeb2352eb5062656291f 495 Gene3D G3DSA:2.60.120.260 364 489 2.4E-19 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS34255 68d24985c58deeb2352eb5062656291f 495 Pfam PF04616 Glycosyl hydrolases family 43 56 339 1.1E-63 T 29-03-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 SMALA_RS34255 68d24985c58deeb2352eb5062656291f 495 SUPERFAMILY SSF75005 46 340 4.71E-57 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain SMALA_RS34255 68d24985c58deeb2352eb5062656291f 495 Gene3D G3DSA:2.115.10.20 48 357 4.2E-54 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain SMALA_RS03730 06409688e3262e285531f107985404eb 138 Gene3D G3DSA:3.10.180.10 8 138 2.0E-27 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS03730 06409688e3262e285531f107985404eb 138 SUPERFAMILY SSF54593 6 136 3.76E-28 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS03730 06409688e3262e285531f107985404eb 138 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 132 3.7E-15 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMALA_RS32710 720e68c2ffa5c021a7b755dc21a0a7fb 162 Gene3D G3DSA:2.30.110.10 5 160 3.4E-15 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS32710 720e68c2ffa5c021a7b755dc21a0a7fb 162 SUPERFAMILY SSF50475 13 149 4.32E-17 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS29030 212d32a07e38d81b5747bf0fd5610504 253 Gene3D G3DSA:1.10.10.10 171 244 5.4E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS29030 212d32a07e38d81b5747bf0fd5610504 253 SUPERFAMILY SSF46785 176 246 2.04E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS29030 212d32a07e38d81b5747bf0fd5610504 253 Gene3D G3DSA:3.90.79.10 13 170 1.4E-40 T 29-03-2018 SMALA_RS29030 212d32a07e38d81b5747bf0fd5610504 253 Pfam PF00293 NUDIX domain 15 138 2.4E-18 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SMALA_RS29030 212d32a07e38d81b5747bf0fd5610504 253 ProSitePatterns PS00893 Nudix box signature. 48 69 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 SMALA_RS29030 212d32a07e38d81b5747bf0fd5610504 253 SUPERFAMILY SSF55811 7 173 8.8E-28 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMALA_RS42050 8053b2efa848d0e046b08002dbd6e83f 428 Gene3D G3DSA:1.20.1250.20 225 417 1.6E-20 T 29-03-2018 SMALA_RS42050 8053b2efa848d0e046b08002dbd6e83f 428 Pfam PF05977 Transmembrane secretion effector 34 413 2.4E-23 T 29-03-2018 IPR010290 Transmembrane secretion effector SMALA_RS42050 8053b2efa848d0e046b08002dbd6e83f 428 Gene3D G3DSA:1.20.1250.20 22 224 1.5E-14 T 29-03-2018 SMALA_RS42050 8053b2efa848d0e046b08002dbd6e83f 428 SUPERFAMILY SSF103473 26 415 9.29E-43 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS41230 efac485c029133fb70f23028b0bc5a73 314 SUPERFAMILY SSF52402 162 313 1.76E-16 T 29-03-2018 SMALA_RS41230 efac485c029133fb70f23028b0bc5a73 314 Pfam PF00582 Universal stress protein family 162 312 1.1E-10 T 29-03-2018 IPR006016 UspA GO:0006950 SMALA_RS41230 efac485c029133fb70f23028b0bc5a73 314 Pfam PF00582 Universal stress protein family 4 136 3.6E-23 T 29-03-2018 IPR006016 UspA GO:0006950 SMALA_RS41230 efac485c029133fb70f23028b0bc5a73 314 Gene3D G3DSA:3.40.50.620 159 314 1.0E-20 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS41230 efac485c029133fb70f23028b0bc5a73 314 PRINTS PR01438 Universal stress protein signature 2 20 1.4E-10 T 29-03-2018 IPR006015 Universal stress protein A SMALA_RS41230 efac485c029133fb70f23028b0bc5a73 314 PRINTS PR01438 Universal stress protein signature 96 108 1.4E-10 T 29-03-2018 IPR006015 Universal stress protein A SMALA_RS41230 efac485c029133fb70f23028b0bc5a73 314 PRINTS PR01438 Universal stress protein signature 114 136 1.4E-10 T 29-03-2018 IPR006015 Universal stress protein A SMALA_RS41230 efac485c029133fb70f23028b0bc5a73 314 SUPERFAMILY SSF52402 5 137 1.09E-23 T 29-03-2018 SMALA_RS41230 efac485c029133fb70f23028b0bc5a73 314 Gene3D G3DSA:3.40.50.620 1 146 4.6E-26 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS27215 5b4d770377d617b9e72f02827c765e67 710 SUPERFAMILY SSF88713 86 196 8.62E-31 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 SMALA_RS27215 5b4d770377d617b9e72f02827c765e67 710 Pfam PF01522 Polysaccharide deacetylase 93 194 2.4E-20 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 SMALA_RS27215 5b4d770377d617b9e72f02827c765e67 710 Pfam PF13641 Glycosyltransferase like family 2 345 564 5.2E-37 T 29-03-2018 SMALA_RS27215 5b4d770377d617b9e72f02827c765e67 710 Gene3D G3DSA:3.90.550.10 321 578 2.6E-66 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS27215 5b4d770377d617b9e72f02827c765e67 710 SUPERFAMILY SSF53448 343 599 1.09E-62 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS27215 5b4d770377d617b9e72f02827c765e67 710 Gene3D G3DSA:3.20.20.370 79 281 1.8E-27 T 29-03-2018 SMALA_RS06930 87024968b94b75757e2f3537e7549371 90 Gene3D G3DSA:3.30.40.10 3 90 1.0E-15 T 29-03-2018 IPR013083 Zinc finger, RING/FYVE/PHD-type SMALA_RS06930 87024968b94b75757e2f3537e7549371 90 SUPERFAMILY SSF57850 7 89 9.06E-20 T 29-03-2018 SMALA_RS06930 87024968b94b75757e2f3537e7549371 90 Pfam PF02148 Zn-finger in ubiquitin-hydrolases and other protein 23 87 9.6E-9 T 29-03-2018 IPR001607 Zinc finger, UBP-type GO:0008270 SMALA_RS14940 6cf0911b85da52d5982ad0759fa0e4c4 257 Gene3D G3DSA:2.40.260.10 39 257 3.4E-41 T 29-03-2018 IPR023365 Sortase domain SMALA_RS14940 6cf0911b85da52d5982ad0759fa0e4c4 257 Pfam PF04203 Sortase family 109 245 9.5E-28 T 29-03-2018 IPR005754 Sortase family SMALA_RS14940 6cf0911b85da52d5982ad0759fa0e4c4 257 SUPERFAMILY SSF63817 102 246 4.58E-30 T 29-03-2018 IPR023365 Sortase domain SMALA_RS14940 6cf0911b85da52d5982ad0759fa0e4c4 257 TIGRFAM TIGR01076 sortase_fam: sortase 108 244 3.1E-12 T 29-03-2018 IPR005754 Sortase family SMALA_RS42505 1977a0a430b2eac30db6511784853fb6 304 Gene3D G3DSA:3.20.20.30 5 233 5.5E-22 T 29-03-2018 SMALA_RS42505 1977a0a430b2eac30db6511784853fb6 304 Pfam PF00296 Luciferase-like monooxygenase 14 242 1.4E-16 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS42505 1977a0a430b2eac30db6511784853fb6 304 SUPERFAMILY SSF51679 10 286 4.88E-32 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS42505 1977a0a430b2eac30db6511784853fb6 304 Gene3D G3DSA:3.20.20.120 234 299 0.01 T 29-03-2018 IPR029065 Enolase C-terminal domain-like SMALA_RS20335 d0fcc2cb06c40794e86aad23524da02e 262 Gene3D G3DSA:3.40.190.10 37 131 9.3E-18 T 29-03-2018 SMALA_RS20335 d0fcc2cb06c40794e86aad23524da02e 262 SUPERFAMILY SSF53850 41 262 9.97E-52 T 29-03-2018 SMALA_RS20335 d0fcc2cb06c40794e86aad23524da02e 262 PIRSF PIRSF004846 3 262 5.1E-65 T 29-03-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689|GO:0030288 SMALA_RS20335 d0fcc2cb06c40794e86aad23524da02e 262 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 47 256 2.9E-39 T 29-03-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689|GO:0030288 SMALA_RS20335 d0fcc2cb06c40794e86aad23524da02e 262 Pfam PF13531 Bacterial extracellular solute-binding protein 42 259 6.8E-41 T 29-03-2018 SMALA_RS20335 d0fcc2cb06c40794e86aad23524da02e 262 Gene3D G3DSA:3.40.190.10 132 209 4.3E-22 T 29-03-2018 SMALA_RS20335 d0fcc2cb06c40794e86aad23524da02e 262 Gene3D G3DSA:3.40.190.10 210 258 5.1E-4 T 29-03-2018 SMALA_RS38605 ca08079061a91041bcb0d7c01ae3ece0 259 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMALA_RS38605 ca08079061a91041bcb0d7c01ae3ece0 259 SUPERFAMILY SSF51735 10 257 2.91E-65 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS38605 ca08079061a91041bcb0d7c01ae3ece0 259 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 105 125 1.0E-34 T 29-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 SMALA_RS38605 ca08079061a91041bcb0d7c01ae3ece0 259 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 170 193 1.0E-34 T 29-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 SMALA_RS38605 ca08079061a91041bcb0d7c01ae3ece0 259 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 209 228 1.0E-34 T 29-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 SMALA_RS38605 ca08079061a91041bcb0d7c01ae3ece0 259 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 235 254 1.0E-34 T 29-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 SMALA_RS38605 ca08079061a91041bcb0d7c01ae3ece0 259 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 15 32 1.0E-34 T 29-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 SMALA_RS38605 ca08079061a91041bcb0d7c01ae3ece0 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 256 3.1E-50 T 29-03-2018 SMALA_RS38605 ca08079061a91041bcb0d7c01ae3ece0 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 1.7E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS38605 ca08079061a91041bcb0d7c01ae3ece0 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 1.7E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS38605 ca08079061a91041bcb0d7c01ae3ece0 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 1.7E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS38605 ca08079061a91041bcb0d7c01ae3ece0 259 Gene3D G3DSA:3.40.50.720 9 259 1.8E-61 T 29-03-2018 SMALA_RS14900 189d2e2a3c2ec8e0690ed72c94d35e61 62 Pfam PF14013 MT0933-like antitoxin protein 4 52 3.4E-15 T 29-03-2018 IPR028037 Antitoxin Rv0909/MT0933 SMALA_RS38815 32a622e2e819bb3e0deab3a5add9ab96 430 SUPERFAMILY SSF158472 161 211 1.96E-5 T 29-03-2018 SMALA_RS38815 32a622e2e819bb3e0deab3a5add9ab96 430 Pfam PF00512 His Kinase A (phospho-acceptor) domain 216 275 6.7E-8 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS38815 32a622e2e819bb3e0deab3a5add9ab96 430 Gene3D G3DSA:1.10.287.130 204 274 6.7E-9 T 29-03-2018 SMALA_RS38815 32a622e2e819bb3e0deab3a5add9ab96 430 SMART SM00387 323 424 2.7E-13 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS38815 32a622e2e819bb3e0deab3a5add9ab96 430 SUPERFAMILY SSF55874 294 425 2.01E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS38815 32a622e2e819bb3e0deab3a5add9ab96 430 SMART SM00304 161 213 4.0E-7 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMALA_RS38815 32a622e2e819bb3e0deab3a5add9ab96 430 SUPERFAMILY SSF47384 197 275 1.73E-10 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS38815 32a622e2e819bb3e0deab3a5add9ab96 430 SMART SM00388 214 278 3.8E-9 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMALA_RS38815 32a622e2e819bb3e0deab3a5add9ab96 430 Gene3D G3DSA:3.30.565.10 284 429 9.9E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS38815 32a622e2e819bb3e0deab3a5add9ab96 430 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 328 423 6.1E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS31830 e54726043816bafae67ff61df19bc7d4 386 Gene3D G3DSA:3.20.20.30 1 369 4.9E-90 T 29-03-2018 SMALA_RS31830 e54726043816bafae67ff61df19bc7d4 386 Pfam PF00296 Luciferase-like monooxygenase 4 333 9.4E-85 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS31830 e54726043816bafae67ff61df19bc7d4 386 SUPERFAMILY SSF51679 4 363 1.44E-91 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS42540 6164411bce62a12acc400b6d9a5565f1 345 Pfam PF00248 Aldo/keto reductase family 39 336 4.9E-64 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS42540 6164411bce62a12acc400b6d9a5565f1 345 Gene3D G3DSA:3.20.20.100 24 339 2.4E-82 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS42540 6164411bce62a12acc400b6d9a5565f1 345 SUPERFAMILY SSF51430 22 336 4.19E-83 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS22340 93bffcaf32b26bd6f412858680a49b04 304 PRINTS PR00783 Major intrinsic protein family signature 104 128 5.8E-24 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMALA_RS22340 93bffcaf32b26bd6f412858680a49b04 304 PRINTS PR00783 Major intrinsic protein family signature 222 244 5.8E-24 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMALA_RS22340 93bffcaf32b26bd6f412858680a49b04 304 PRINTS PR00783 Major intrinsic protein family signature 56 75 5.8E-24 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMALA_RS22340 93bffcaf32b26bd6f412858680a49b04 304 PRINTS PR00783 Major intrinsic protein family signature 141 160 5.8E-24 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMALA_RS22340 93bffcaf32b26bd6f412858680a49b04 304 PRINTS PR00783 Major intrinsic protein family signature 259 279 5.8E-24 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMALA_RS22340 93bffcaf32b26bd6f412858680a49b04 304 Pfam PF00230 Major intrinsic protein 58 273 9.0E-30 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMALA_RS22340 93bffcaf32b26bd6f412858680a49b04 304 Gene3D G3DSA:1.20.1080.10 18 292 2.7E-43 T 29-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 SMALA_RS22340 93bffcaf32b26bd6f412858680a49b04 304 SUPERFAMILY SSF81338 52 283 2.35E-36 T 29-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 SMALA_RS22340 93bffcaf32b26bd6f412858680a49b04 304 ProSitePatterns PS00221 MIP family signature. 122 130 - T 29-03-2018 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMALA_RS25075 064075f2c1ae2e229fb0d30d1f00f605 248 Gene3D G3DSA:3.40.50.1820 2 247 2.2E-18 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS25075 064075f2c1ae2e229fb0d30d1f00f605 248 Pfam PF12697 Alpha/beta hydrolase family 3 234 2.1E-10 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS25075 064075f2c1ae2e229fb0d30d1f00f605 248 SUPERFAMILY SSF53474 2 244 1.89E-21 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS03605 2f2a0482d8ded78b775cf039f513233f 348 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 5 182 3.3E-21 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain SMALA_RS03605 2f2a0482d8ded78b775cf039f513233f 348 SUPERFAMILY SSF52266 2 192 3.82E-32 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain SMALA_RS03605 2f2a0482d8ded78b775cf039f513233f 348 Gene3D G3DSA:3.40.50.1110 1 195 6.1E-28 T 29-03-2018 SMALA_RS03845 b4e396b209ccfc921f8cd907bbbf18c9 472 Gene3D G3DSA:2.60.60.30 283 447 3.1E-26 T 29-03-2018 SMALA_RS03845 b4e396b209ccfc921f8cd907bbbf18c9 472 Pfam PF02342 TerD domain 2 168 8.0E-47 T 29-03-2018 IPR003325 TerD domain GO:0006950 SMALA_RS03845 b4e396b209ccfc921f8cd907bbbf18c9 472 PIRSF PIRSF037118 203 472 1.0E-97 T 29-03-2018 IPR017115 Tellurite resistance, TerA SMALA_RS03845 b4e396b209ccfc921f8cd907bbbf18c9 472 PIRSF PIRSF037118 1 208 3.1E-74 T 29-03-2018 IPR017115 Tellurite resistance, TerA SMALA_RS03845 b4e396b209ccfc921f8cd907bbbf18c9 472 Gene3D G3DSA:2.60.60.30 13 167 2.2E-46 T 29-03-2018 SMALA_RS41060 60d290f26cf16f939d73a1a6ba43b13a 466 Gene3D G3DSA:3.20.20.30 11 465 3.8E-105 T 29-03-2018 SMALA_RS41060 60d290f26cf16f939d73a1a6ba43b13a 466 PIRSF PIRSF000337 12 458 1.3E-137 T 29-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 SMALA_RS41060 60d290f26cf16f939d73a1a6ba43b13a 466 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 17 443 2.2E-152 T 29-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 SMALA_RS41060 60d290f26cf16f939d73a1a6ba43b13a 466 SUPERFAMILY SSF51679 12 447 1.96E-115 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS41060 60d290f26cf16f939d73a1a6ba43b13a 466 Pfam PF00296 Luciferase-like monooxygenase 34 402 4.5E-62 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS29655 dc480a9265c8a7546255ae49e16b9701 210 SUPERFAMILY SSF51569 3 205 3.3E-50 T 29-03-2018 SMALA_RS29655 dc480a9265c8a7546255ae49e16b9701 210 Pfam PF01081 KDPG and KHG aldolase 6 183 1.9E-36 T 29-03-2018 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 SMALA_RS29655 dc480a9265c8a7546255ae49e16b9701 210 Gene3D G3DSA:3.20.20.70 1 210 3.5E-30 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS30550 f8c08b63c08a206a753e614e97a8fa12 259 Pfam PF09339 IclR helix-turn-helix domain 20 71 1.3E-17 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMALA_RS30550 f8c08b63c08a206a753e614e97a8fa12 259 SUPERFAMILY SSF46785 18 86 8.99E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS30550 f8c08b63c08a206a753e614e97a8fa12 259 Pfam PF01614 Bacterial transcriptional regulator 133 254 7.6E-33 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal SMALA_RS30550 f8c08b63c08a206a753e614e97a8fa12 259 SMART SM00346 18 105 4.1E-22 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMALA_RS30550 f8c08b63c08a206a753e614e97a8fa12 259 SUPERFAMILY SSF55781 75 257 4.77E-53 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS30550 f8c08b63c08a206a753e614e97a8fa12 259 Gene3D G3DSA:1.10.10.10 1 78 7.3E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS30550 f8c08b63c08a206a753e614e97a8fa12 259 Gene3D G3DSA:3.30.450.40 87 259 2.2E-55 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS06660 21bdf1a2b701e71b95b8f2668a3043f7 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 64 2.5E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS06660 21bdf1a2b701e71b95b8f2668a3043f7 202 Gene3D G3DSA:1.10.10.60 5 65 1.5E-16 T 29-03-2018 SMALA_RS06660 21bdf1a2b701e71b95b8f2668a3043f7 202 SUPERFAMILY SSF46689 8 77 8.21E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS06660 21bdf1a2b701e71b95b8f2668a3043f7 202 Gene3D G3DSA:1.10.357.10 66 198 1.2E-21 T 29-03-2018 SMALA_RS06660 21bdf1a2b701e71b95b8f2668a3043f7 202 SUPERFAMILY SSF48498 85 200 3.86E-24 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS06660 21bdf1a2b701e71b95b8f2668a3043f7 202 ProSitePatterns PS01081 TetR-type HTH domain signature. 32 62 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site SMALA_RS19105 5f4b9bf1349d77d9e781f213b9d170ae 432 Gene3D G3DSA:3.90.550.10 14 269 2.5E-32 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS19105 5f4b9bf1349d77d9e781f213b9d170ae 432 Pfam PF04138 GtrA-like protein 299 416 1.6E-13 T 29-03-2018 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 SMALA_RS19105 5f4b9bf1349d77d9e781f213b9d170ae 432 SUPERFAMILY SSF53448 29 243 4.78E-35 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS19105 5f4b9bf1349d77d9e781f213b9d170ae 432 Pfam PF00535 Glycosyl transferase family 2 34 201 2.1E-22 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 SMALA_RS05465 fac25afb1e89162f354656204b71333b 325 SUPERFAMILY SSF53474 28 319 6.97E-60 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS05465 fac25afb1e89162f354656204b71333b 325 Pfam PF07859 alpha/beta hydrolase fold 88 294 2.0E-50 T 29-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 SMALA_RS05465 fac25afb1e89162f354656204b71333b 325 Gene3D G3DSA:3.40.50.1820 2 325 7.4E-55 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS22825 ea9b9b5c561423fba18c418a6d1b1506 222 SUPERFAMILY SSF53067 110 204 2.46E-10 T 29-03-2018 SMALA_RS22825 ea9b9b5c561423fba18c418a6d1b1506 222 SUPERFAMILY SSF53067 3 103 5.18E-22 T 29-03-2018 SMALA_RS22825 ea9b9b5c561423fba18c418a6d1b1506 222 Gene3D G3DSA:3.30.420.40 1 140 2.6E-35 T 29-03-2018 SMALA_RS22825 ea9b9b5c561423fba18c418a6d1b1506 222 Pfam PF00814 Glycoprotease family 30 147 1.4E-28 T 29-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SMALA_RS22825 ea9b9b5c561423fba18c418a6d1b1506 222 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 3 206 2.1E-57 T 29-03-2018 IPR022496 tRNA threonylcarbamoyl adenosine modification protein TsaB GO:0002949 SMALA_RS07845 86b045fbb68e720510d89150c63c289e 286 Pfam PF15575 Immunity protein 49 58 275 3.6E-73 T 29-03-2018 IPR029074 Immunity protein 49 SMALA_RS29965 6230a8245a1ce0f920c24f191bd80da3 240 SUPERFAMILY SSF53448 7 220 3.04E-37 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS29965 6230a8245a1ce0f920c24f191bd80da3 240 Gene3D G3DSA:3.90.550.10 2 232 1.2E-30 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS29965 6230a8245a1ce0f920c24f191bd80da3 240 Pfam PF00535 Glycosyl transferase family 2 13 162 3.8E-20 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 SMALA_RS01180 3e7ff904e09e62b7ee8eb5726862594c 353 SUPERFAMILY SSF82689 242 341 1.96E-17 T 29-03-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 SMALA_RS01180 3e7ff904e09e62b7ee8eb5726862594c 353 Pfam PF00924 Mechanosensitive ion channel 126 330 5.8E-40 T 29-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 SMALA_RS01180 3e7ff904e09e62b7ee8eb5726862594c 353 Gene3D G3DSA:2.30.30.60 186 236 1.2E-7 T 29-03-2018 SMALA_RS01180 3e7ff904e09e62b7ee8eb5726862594c 353 Gene3D G3DSA:3.30.70.100 237 335 3.3E-13 T 29-03-2018 SMALA_RS01180 3e7ff904e09e62b7ee8eb5726862594c 353 SUPERFAMILY SSF82861 85 167 4.84E-12 T 29-03-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 SMALA_RS01180 3e7ff904e09e62b7ee8eb5726862594c 353 SUPERFAMILY SSF50182 168 234 5.23E-12 T 29-03-2018 IPR010920 LSM domain SMALA_RS22345 bd992e0acad653e5ec1af5a6f2338ee6 503 Gene3D G3DSA:2.60.40.1180 431 503 9.6E-17 T 29-03-2018 SMALA_RS22345 bd992e0acad653e5ec1af5a6f2338ee6 503 SUPERFAMILY SSF51011 433 498 6.4E-6 T 29-03-2018 SMALA_RS22345 bd992e0acad653e5ec1af5a6f2338ee6 503 Pfam PF02055 Glycosyl hydrolase family 30 TIM-barrel domain 99 396 5.8E-35 T 29-03-2018 IPR033453 Glycosyl hydrolase family 30, TIM-barrel domain Reactome: R-HSA-1660662|Reactome: R-HSA-390471 SMALA_RS22345 bd992e0acad653e5ec1af5a6f2338ee6 503 Pfam PF17189 Glycosyl hydrolase family 30 beta sandwich domain 437 496 2.1E-13 T 29-03-2018 IPR033452 Glycosyl hydrolase family 30, beta sandwich domain Reactome: R-HSA-1660662|Reactome: R-HSA-390471 SMALA_RS22345 bd992e0acad653e5ec1af5a6f2338ee6 503 PRINTS PR00843 Glycosyl hydrolase family 30 signature 87 107 4.3E-6 T 29-03-2018 IPR001139 Glycoside hydrolase family 30 GO:0004348|GO:0006665 Reactome: R-HSA-1660662|Reactome: R-HSA-390471 SMALA_RS22345 bd992e0acad653e5ec1af5a6f2338ee6 503 PRINTS PR00843 Glycosyl hydrolase family 30 signature 222 239 4.3E-6 T 29-03-2018 IPR001139 Glycoside hydrolase family 30 GO:0004348|GO:0006665 Reactome: R-HSA-1660662|Reactome: R-HSA-390471 SMALA_RS22345 bd992e0acad653e5ec1af5a6f2338ee6 503 Gene3D G3DSA:3.20.20.80 95 430 3.4E-82 T 29-03-2018 SMALA_RS22345 bd992e0acad653e5ec1af5a6f2338ee6 503 SUPERFAMILY SSF51445 98 438 3.94E-66 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS00520 7bfc1e3332676f544418e35ec33f03ac 741 Gene3D G3DSA:3.90.1170.50 1 127 1.2E-27 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMALA_RS00520 7bfc1e3332676f544418e35ec33f03ac 741 SMART SM01008 16 128 3.8E-30 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMALA_RS00520 7bfc1e3332676f544418e35ec33f03ac 741 Gene3D G3DSA:3.30.365.10 568 737 4.5E-44 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMALA_RS00520 7bfc1e3332676f544418e35ec33f03ac 741 Gene3D G3DSA:3.30.365.10 432 567 1.4E-33 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMALA_RS00520 7bfc1e3332676f544418e35ec33f03ac 741 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 153 676 6.6E-120 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMALA_RS00520 7bfc1e3332676f544418e35ec33f03ac 741 Gene3D G3DSA:3.30.365.10 154 260 5.0E-30 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMALA_RS00520 7bfc1e3332676f544418e35ec33f03ac 741 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 16 125 3.4E-21 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMALA_RS00520 7bfc1e3332676f544418e35ec33f03ac 741 SUPERFAMILY SSF54665 2 125 7.33E-32 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMALA_RS00520 7bfc1e3332676f544418e35ec33f03ac 741 Gene3D G3DSA:3.30.365.10 261 430 8.6E-31 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMALA_RS00520 7bfc1e3332676f544418e35ec33f03ac 741 SUPERFAMILY SSF56003 151 736 6.67E-158 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMALA_RS31835 fdafa07f00bf11cc10c3b2190d238aca 399 PIRSF PIRSF016578 7 394 2.7E-34 T 29-03-2018 SMALA_RS31835 fdafa07f00bf11cc10c3b2190d238aca 399 Gene3D G3DSA:2.40.110.10 124 222 1.7E-22 T 29-03-2018 SMALA_RS31835 fdafa07f00bf11cc10c3b2190d238aca 399 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 19 120 9.8E-12 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS31835 fdafa07f00bf11cc10c3b2190d238aca 399 TIGRFAM TIGR04022 sulfur_SfnB: sulfur acquisition oxidoreductase, SfnB family 8 398 2.0E-170 T 29-03-2018 IPR023922 Sulphate-starvation-induced SfnB SMALA_RS31835 fdafa07f00bf11cc10c3b2190d238aca 399 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 242 373 9.2E-18 T 29-03-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain SMALA_RS31835 fdafa07f00bf11cc10c3b2190d238aca 399 SUPERFAMILY SSF56645 20 224 1.13E-50 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMALA_RS31835 fdafa07f00bf11cc10c3b2190d238aca 399 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 133 215 7.0E-14 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 SMALA_RS31835 fdafa07f00bf11cc10c3b2190d238aca 399 Gene3D G3DSA:1.10.540.10 13 123 5.0E-19 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS31835 fdafa07f00bf11cc10c3b2190d238aca 399 SUPERFAMILY SSF47203 237 396 1.5E-23 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMALA_RS31835 fdafa07f00bf11cc10c3b2190d238aca 399 Gene3D G3DSA:1.20.140.10 223 398 2.9E-25 T 29-03-2018 SMALA_RS08780 81468c7c7cb97e294a33f4fa9fb32e1d 349 Gene3D G3DSA:1.10.3470.10 20 349 3.7E-70 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SMALA_RS08780 81468c7c7cb97e294a33f4fa9fb32e1d 349 Pfam PF01032 FecCD transport family 36 343 7.1E-89 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 SMALA_RS08780 81468c7c7cb97e294a33f4fa9fb32e1d 349 SUPERFAMILY SSF81345 19 344 2.35E-79 T 29-03-2018 IPR029022 ABC transporter, BtuC-like SMALA_RS31080 e542ed2e70733a2558e4682644d26bd9 154 Gene3D G3DSA:3.30.530.20 3 153 7.1E-27 T 29-03-2018 IPR023393 START-like domain SMALA_RS31080 e542ed2e70733a2558e4682644d26bd9 154 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 6 137 3.2E-15 T 29-03-2018 IPR019587 Polyketide cyclase/dehydrase SMALA_RS31080 e542ed2e70733a2558e4682644d26bd9 154 SUPERFAMILY SSF55961 1 150 7.1E-38 T 29-03-2018 SMALA_RS18440 70af182b3e4063262a1ef7534645a635 150 Pfam PF01989 Protein of unknown function DUF126 32 111 2.6E-24 T 29-03-2018 IPR002840 Aconitase X swivel domain, putative SMALA_RS18440 70af182b3e4063262a1ef7534645a635 150 SUPERFAMILY SSF52016 10 140 3.77E-38 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel SMALA_RS18440 70af182b3e4063262a1ef7534645a635 150 PIRSF PIRSF004966 8 141 2.5E-37 T 29-03-2018 IPR012016 Aconitase X subunit 2, putative SMALA_RS18440 70af182b3e4063262a1ef7534645a635 150 Gene3D G3DSA:3.50.30.10 11 139 5.3E-45 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 SMALA_RS04245 c6a501aef40b9f4d19d25c6219026030 336 Pfam PF03060 Nitronate monooxygenase 88 310 3.8E-38 T 29-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 SMALA_RS04245 c6a501aef40b9f4d19d25c6219026030 336 Pfam PF03060 Nitronate monooxygenase 10 86 2.3E-11 T 29-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 SMALA_RS04245 c6a501aef40b9f4d19d25c6219026030 336 SUPERFAMILY SSF51412 7 317 8.09E-52 T 29-03-2018 SMALA_RS04245 c6a501aef40b9f4d19d25c6219026030 336 Gene3D G3DSA:3.20.20.70 4 334 3.7E-45 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS08950 91b5e733cd6693202d2242587817515c 283 Pfam PF06283 Trehalose utilisation 51 257 5.2E-32 T 29-03-2018 IPR029010 ThuA-like domain SMALA_RS08950 91b5e733cd6693202d2242587817515c 283 SUPERFAMILY SSF52317 44 281 1.42E-25 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS08950 91b5e733cd6693202d2242587817515c 283 Gene3D G3DSA:3.40.50.880 38 283 1.2E-29 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS31535 7e7b5b0766fe38f71e77bb4395e4d152 289 SUPERFAMILY SSF47413 32 80 1.54E-8 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS31535 7e7b5b0766fe38f71e77bb4395e4d152 289 SMART SM00530 11 84 2.6E-10 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS31535 7e7b5b0766fe38f71e77bb4395e4d152 289 Pfam PF13560 Helix-turn-helix domain 7 87 2.5E-20 T 29-03-2018 SMALA_RS31535 7e7b5b0766fe38f71e77bb4395e4d152 289 Gene3D G3DSA:1.10.260.40 1 83 1.9E-16 T 29-03-2018 SMALA_RS18045 e7ac155882759c042f49183af125ed53 380 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 1 380 40.407 T 29-03-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS18045 e7ac155882759c042f49183af125ed53 380 Gene3D G3DSA:1.10.645.10 209 373 3.4E-27 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS18045 e7ac155882759c042f49183af125ed53 380 Gene3D G3DSA:1.10.645.10 13 196 1.2E-49 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS18045 e7ac155882759c042f49183af125ed53 380 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 53 64 - T 29-03-2018 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS18045 e7ac155882759c042f49183af125ed53 380 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 131 380 2.3E-67 T 29-03-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS18045 e7ac155882759c042f49183af125ed53 380 SUPERFAMILY SSF56762 26 379 2.09E-100 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS42770 26f01d9346faaaa910a10e4d802910b2 329 Gene3D G3DSA:1.20.140.10 154 263 1.6E-12 T 29-03-2018 SMALA_RS42770 26f01d9346faaaa910a10e4d802910b2 329 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 159 258 5.8E-8 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMALA_RS42770 26f01d9346faaaa910a10e4d802910b2 329 SUPERFAMILY SSF47203 157 259 2.58E-16 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMALA_RS31730 76a6caf8aab8f3c3254473f90975ae7c 554 TIGRFAM TIGR00680 kdpA: K+-transporting ATPase, A subunit 5 553 1.1E-211 T 29-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 SMALA_RS31730 76a6caf8aab8f3c3254473f90975ae7c 554 Hamap MF_00275 Potassium-transporting ATPase potassium-binding subunit [kdpA]. 4 554 32.219 T 29-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 SMALA_RS31730 76a6caf8aab8f3c3254473f90975ae7c 554 Pfam PF03814 Potassium-transporting ATPase A subunit 14 553 5.0E-227 T 29-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 SMALA_RS31730 76a6caf8aab8f3c3254473f90975ae7c 554 PIRSF PIRSF001294 4 554 1.5E-217 T 29-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 SMALA_RS24460 52be45fad703353bfe115322be127c38 284 Gene3D G3DSA:1.10.3720.10 6 269 2.8E-38 T 29-03-2018 SMALA_RS24460 52be45fad703353bfe115322be127c38 284 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 97 272 1.2E-27 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS24460 52be45fad703353bfe115322be127c38 284 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 7 56 8.0E-8 T 29-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain SMALA_RS24460 52be45fad703353bfe115322be127c38 284 SUPERFAMILY SSF161098 76 261 6.41E-23 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS29430 41f177449440835bb01729524dd68032 333 Gene3D G3DSA:3.10.129.10 19 152 0.0049 T 29-03-2018 SMALA_RS29430 41f177449440835bb01729524dd68032 333 Gene3D G3DSA:3.10.129.10 184 329 3.7E-10 T 29-03-2018 SMALA_RS29430 41f177449440835bb01729524dd68032 333 SUPERFAMILY SSF54637 189 276 5.71E-7 T 29-03-2018 IPR029069 HotDog domain SMALA_RS08830 c2a4eb92f2c54b4af16a6b88cd18d7a8 260 Pfam PF07070 SpoOM protein 3 216 1.3E-79 T 29-03-2018 IPR009776 Sporulation stage 0, protein M SMALA_RS02050 f209177681bc0e1af5502bf87ff438b0 149 SUPERFAMILY SSF50685 67 148 8.68E-8 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain SMALA_RS02050 f209177681bc0e1af5502bf87ff438b0 149 Gene3D G3DSA:2.40.40.10 23 149 3.2E-11 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain SMALA_RS02050 f209177681bc0e1af5502bf87ff438b0 149 Pfam PF03330 Lytic transglycolase 57 143 8.9E-9 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain SMALA_RS23750 f2dfd129f9291ad61a34d657127381f4 300 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 8 273 2.3E-101 T 29-03-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 SMALA_RS23750 f2dfd129f9291ad61a34d657127381f4 300 Pfam PF00483 Nucleotidyl transferase 10 273 1.2E-26 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 SMALA_RS23750 f2dfd129f9291ad61a34d657127381f4 300 Gene3D G3DSA:3.90.550.10 1 300 2.2E-57 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS23750 f2dfd129f9291ad61a34d657127381f4 300 SUPERFAMILY SSF53448 10 291 5.42E-62 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS39885 02220619f33d0b4d49719d045408e621 460 Gene3D G3DSA:3.40.350.10 58 204 0.0017 T 29-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal SMALA_RS39885 02220619f33d0b4d49719d045408e621 460 SUPERFAMILY SSF55920 222 457 1.44E-27 T 29-03-2018 IPR000994 Peptidase M24 SMALA_RS39885 02220619f33d0b4d49719d045408e621 460 Gene3D G3DSA:3.90.230.10 205 460 1.1E-23 T 29-03-2018 SMALA_RS39885 02220619f33d0b4d49719d045408e621 460 Pfam PF00557 Metallopeptidase family M24 239 441 1.6E-11 T 29-03-2018 IPR000994 Peptidase M24 SMALA_RS23275 95ac3654d05420ffaaacf453c5c73e46 838 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 598 611 1.5E-13 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 SMALA_RS23275 95ac3654d05420ffaaacf453c5c73e46 838 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 514 525 1.5E-13 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 SMALA_RS23275 95ac3654d05420ffaaacf453c5c73e46 838 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 571 588 1.5E-13 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 SMALA_RS23275 95ac3654d05420ffaaacf453c5c73e46 838 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 505 713 3.9E-32 T 29-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 SMALA_RS23275 95ac3654d05420ffaaacf453c5c73e46 838 Gene3D G3DSA:3.40.710.10 233 775 6.0E-44 T 29-03-2018 SMALA_RS23275 95ac3654d05420ffaaacf453c5c73e46 838 SUPERFAMILY SSF56601 440 715 2.17E-39 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMALA_RS24470 02b4e08dddfd689302e8eee47ddadf0d 670 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 19 355 6.0E-49 T 29-03-2018 IPR005674 CocE/Serine esterase GO:0016787 SMALA_RS24470 02b4e08dddfd689302e8eee47ddadf0d 670 SMART SM00939 294 520 7.1E-67 T 29-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 SMALA_RS24470 02b4e08dddfd689302e8eee47ddadf0d 670 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 307 517 1.5E-42 T 29-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 SMALA_RS24470 02b4e08dddfd689302e8eee47ddadf0d 670 SUPERFAMILY SSF49785 294 524 1.02E-49 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS24470 02b4e08dddfd689302e8eee47ddadf0d 670 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 22 276 1.1E-67 T 29-03-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 SMALA_RS24470 02b4e08dddfd689302e8eee47ddadf0d 670 Gene3D G3DSA:2.60.120.260 310 533 6.4E-58 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS24470 02b4e08dddfd689302e8eee47ddadf0d 670 SUPERFAMILY SSF53474 9 341 2.18E-68 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS24470 02b4e08dddfd689302e8eee47ddadf0d 670 Gene3D G3DSA:3.40.50.1820 7 309 1.5E-41 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS06850 fcd8c66113c556b9f181564ea08c7d96 386 Gene3D G3DSA:3.90.1150.10 242 386 4.7E-18 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS06850 fcd8c66113c556b9f181564ea08c7d96 386 SUPERFAMILY SSF53383 9 383 1.18E-95 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS06850 fcd8c66113c556b9f181564ea08c7d96 386 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 20 372 2.9E-112 T 29-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase SMALA_RS06850 fcd8c66113c556b9f181564ea08c7d96 386 Gene3D G3DSA:3.40.640.10 16 241 1.7E-45 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS06850 fcd8c66113c556b9f181564ea08c7d96 386 PIRSF PIRSF000390 3 385 8.1E-106 T 29-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase SMALA_RS06785 afe16aaad4a8d89fa46b6c6c1903ac7f 219 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 1 89 7.2E-19 T 29-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal SMALA_RS06785 afe16aaad4a8d89fa46b6c6c1903ac7f 219 SUPERFAMILY SSF51735 1 191 1.6E-34 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS06785 afe16aaad4a8d89fa46b6c6c1903ac7f 219 Gene3D G3DSA:3.40.50.720 1 178 1.6E-23 T 29-03-2018 SMALA_RS18790 bfd2aa3bfcb0d7cd58a028f89472ba23 111 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 6 109 4.3E-25 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family SMALA_RS18790 bfd2aa3bfcb0d7cd58a028f89472ba23 111 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 8 102 21.147 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family SMALA_RS18790 bfd2aa3bfcb0d7cd58a028f89472ba23 111 Pfam PF02575 YbaB/EbfC DNA-binding family 15 103 1.2E-31 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family SMALA_RS18790 bfd2aa3bfcb0d7cd58a028f89472ba23 111 SUPERFAMILY SSF82607 10 102 3.14E-27 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family SMALA_RS18790 bfd2aa3bfcb0d7cd58a028f89472ba23 111 Gene3D G3DSA:3.30.1310.10 2 111 3.1E-39 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family SMALA_RS18790 bfd2aa3bfcb0d7cd58a028f89472ba23 111 PIRSF PIRSF004555 6 111 4.3E-34 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family SMALA_RS40625 682dbe35477aff74038e4903e591793a 305 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 251 1.2E-47 T 29-03-2018 SMALA_RS40625 682dbe35477aff74038e4903e591793a 305 Gene3D G3DSA:3.40.50.720 1 44 7.2E-9 T 29-03-2018 SMALA_RS40625 682dbe35477aff74038e4903e591793a 305 Gene3D G3DSA:3.40.50.720 45 276 1.8E-50 T 29-03-2018 SMALA_RS40625 682dbe35477aff74038e4903e591793a 305 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 1.3E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40625 682dbe35477aff74038e4903e591793a 305 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 1.3E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40625 682dbe35477aff74038e4903e591793a 305 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 1.3E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40625 682dbe35477aff74038e4903e591793a 305 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 1.7E-27 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40625 682dbe35477aff74038e4903e591793a 305 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 220 240 1.7E-27 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40625 682dbe35477aff74038e4903e591793a 305 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 1.7E-27 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40625 682dbe35477aff74038e4903e591793a 305 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 1.7E-27 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40625 682dbe35477aff74038e4903e591793a 305 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 1.7E-27 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40625 682dbe35477aff74038e4903e591793a 305 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 1.7E-27 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40625 682dbe35477aff74038e4903e591793a 305 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMALA_RS40625 682dbe35477aff74038e4903e591793a 305 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 192 1.6E-4 T 29-03-2018 SMALA_RS40625 682dbe35477aff74038e4903e591793a 305 SUPERFAMILY SSF51735 3 258 2.97E-64 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS42860 b6d2e2f5e33a7843f41b43e4b7d0beda 373 Gene3D G3DSA:3.20.20.30 1 342 2.6E-71 T 29-03-2018 SMALA_RS42860 b6d2e2f5e33a7843f41b43e4b7d0beda 373 Pfam PF00296 Luciferase-like monooxygenase 1 290 5.4E-57 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS42860 b6d2e2f5e33a7843f41b43e4b7d0beda 373 SUPERFAMILY SSF51679 1 333 5.1E-72 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS42860 b6d2e2f5e33a7843f41b43e4b7d0beda 373 TIGRFAM TIGR04036 LLM_CE1758_fam: putative luciferase-like monooxygenase, FMN-dependent, CE1758 family 1 354 1.9E-202 T 29-03-2018 IPR023934 Luciferase-like monooxygenase, FMN-dependent, putative SMALA_RS11030 40ad4ed7107a0f47c403dcbe763701ee 451 Gene3D G3DSA:3.40.190.10 231 398 6.8E-7 T 29-03-2018 SMALA_RS11030 40ad4ed7107a0f47c403dcbe763701ee 451 SUPERFAMILY SSF53850 34 443 1.85E-54 T 29-03-2018 SMALA_RS11030 40ad4ed7107a0f47c403dcbe763701ee 451 Gene3D G3DSA:3.40.190.10 55 230 3.5E-32 T 29-03-2018 SMALA_RS11030 40ad4ed7107a0f47c403dcbe763701ee 451 Pfam PF01547 Bacterial extracellular solute-binding protein 62 346 3.2E-28 T 29-03-2018 IPR006059 Solute-binding family 1 GO:0006810 SMALA_RS38740 1ed2b8015a4e01b5f0c3d8c312ad1aa7 465 SMART SM01150 10 408 7.4E-172 T 29-03-2018 IPR009770 Domain of unknown function DUF1338 SMALA_RS38740 1ed2b8015a4e01b5f0c3d8c312ad1aa7 465 Gene3D G3DSA:3.10.180.10 58 287 7.8E-4 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS38740 1ed2b8015a4e01b5f0c3d8c312ad1aa7 465 Pfam PF07063 Domain of unknown function (DUF1338) 8 408 6.4E-103 T 29-03-2018 IPR009770 Domain of unknown function DUF1338 SMALA_RS31405 3fb0140dc7fb9bc6e1b4f86ad35bcb72 392 Gene3D G3DSA:3.20.20.150 3 387 8.4E-46 T 29-03-2018 SMALA_RS31405 3fb0140dc7fb9bc6e1b4f86ad35bcb72 392 ProSitePatterns PS00730 AP endonucleases family 2 signature 2. 212 219 - T 29-03-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 SMALA_RS31405 3fb0140dc7fb9bc6e1b4f86ad35bcb72 392 SUPERFAMILY SSF51658 15 252 4.06E-27 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SMALA_RS31405 3fb0140dc7fb9bc6e1b4f86ad35bcb72 392 Pfam PF01261 Xylose isomerase-like TIM barrel 56 234 4.1E-10 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SMALA_RS40620 0c92dbefdcc7628aab6ccaf832db095a 291 Gene3D G3DSA:3.20.20.140 39 291 3.9E-47 T 29-03-2018 SMALA_RS40620 0c92dbefdcc7628aab6ccaf832db095a 291 Pfam PF04909 Amidohydrolase 9 288 7.2E-58 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 SMALA_RS40620 0c92dbefdcc7628aab6ccaf832db095a 291 SUPERFAMILY SSF51556 9 288 5.55E-64 T 29-03-2018 IPR032466 Metal-dependent hydrolase SMALA_RS18545 b8cbe912d35442218e877118064911a7 65 Pfam PF14029 Protein of unknown function (DUF4244) 11 62 4.0E-25 T 29-03-2018 IPR025338 Protein of unknown function DUF4244 SMALA_RS16680 3948e6d2d5bed34c28ec4e7c3d5afb6e 185 Pfam PF09349 OHCU decarboxylase 23 166 5.7E-18 T 29-03-2018 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 SMALA_RS16680 3948e6d2d5bed34c28ec4e7c3d5afb6e 185 Gene3D G3DSA:1.10.3330.10 4 173 1.2E-38 T 29-03-2018 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 SMALA_RS16680 3948e6d2d5bed34c28ec4e7c3d5afb6e 185 SUPERFAMILY SSF158694 19 169 1.02E-27 T 29-03-2018 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 SMALA_RS16035 f224dcb5a31793afcce728da87a677ca 492 Pfam PF01979 Amidohydrolase family 53 465 6.5E-45 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 SMALA_RS16035 f224dcb5a31793afcce728da87a677ca 492 Gene3D G3DSA:2.30.40.10 394 490 2.4E-9 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS16035 f224dcb5a31793afcce728da87a677ca 492 SUPERFAMILY SSF51556 120 412 8.51E-71 T 29-03-2018 IPR032466 Metal-dependent hydrolase SMALA_RS16035 f224dcb5a31793afcce728da87a677ca 492 SUPERFAMILY SSF51556 54 75 8.51E-71 T 29-03-2018 IPR032466 Metal-dependent hydrolase SMALA_RS16035 f224dcb5a31793afcce728da87a677ca 492 SUPERFAMILY SSF51338 415 473 4.61E-9 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS16035 f224dcb5a31793afcce728da87a677ca 492 Gene3D G3DSA:2.30.40.10 3 61 5.4E-4 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS16035 f224dcb5a31793afcce728da87a677ca 492 TIGRFAM TIGR02022 hutF: formiminoglutamate deiminase 109 490 1.3E-141 T 29-03-2018 IPR010252 Formiminoglutamate deiminase SMALA_RS16035 f224dcb5a31793afcce728da87a677ca 492 Gene3D G3DSA:3.20.20.140 62 393 2.0E-44 T 29-03-2018 SMALA_RS19920 5576608c95a5635aa2db430dacc28980 233 SUPERFAMILY SSF47240 5 227 2.68E-59 T 29-03-2018 IPR009078 Ferritin-like superfamily SMALA_RS19920 5576608c95a5635aa2db430dacc28980 233 TIGRFAM TIGR02158 PA_CoA_Oxy3: phenylacetate-CoA oxygenase, PaaI subunit 7 233 3.2E-74 T 29-03-2018 IPR011882 1,2-phenylacetyl-CoA epoxidase, subunit C GO:0010124 SMALA_RS19920 5576608c95a5635aa2db430dacc28980 233 Gene3D G3DSA:1.20.1260.10 2 233 2.6E-60 T 29-03-2018 IPR012347 Ferritin-related SMALA_RS19920 5576608c95a5635aa2db430dacc28980 233 Pfam PF05138 Phenylacetic acid catabolic protein 4 233 5.0E-70 T 29-03-2018 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 SMALA_RS19920 5576608c95a5635aa2db430dacc28980 233 PIRSF PIRSF037834 1 233 1.8E-87 T 29-03-2018 IPR011882 1,2-phenylacetyl-CoA epoxidase, subunit C GO:0010124 SMALA_RS41340 91741994416a3855d6e9b66e2ea9195a 265 Gene3D G3DSA:2.30.40.10 2 68 2.4E-14 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS41340 91741994416a3855d6e9b66e2ea9195a 265 SUPERFAMILY SSF51338 3 63 1.44E-13 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS41340 91741994416a3855d6e9b66e2ea9195a 265 Gene3D G3DSA:3.20.20.140 69 265 1.4E-25 T 29-03-2018 SMALA_RS41340 91741994416a3855d6e9b66e2ea9195a 265 SUPERFAMILY SSF51556 56 261 7.38E-15 T 29-03-2018 IPR032466 Metal-dependent hydrolase SMALA_RS41340 91741994416a3855d6e9b66e2ea9195a 265 Pfam PF07969 Amidohydrolase family 44 234 5.9E-10 T 29-03-2018 IPR013108 Amidohydrolase 3 SMALA_RS40385 f5320902dc8b84c75c478f92b20c6272 333 SUPERFAMILY SSF54506 1 331 1.15E-117 T 29-03-2018 SMALA_RS40385 f5320902dc8b84c75c478f92b20c6272 333 Gene3D G3DSA:3.10.310.10 1 151 4.1E-40 T 29-03-2018 SMALA_RS40385 f5320902dc8b84c75c478f92b20c6272 333 PIRSF PIRSF029792 1 333 5.3E-127 T 29-03-2018 IPR008794 Proline racemase family SMALA_RS40385 f5320902dc8b84c75c478f92b20c6272 333 Pfam PF05544 Proline racemase 10 332 7.2E-127 T 29-03-2018 IPR008794 Proline racemase family SMALA_RS40385 f5320902dc8b84c75c478f92b20c6272 333 Gene3D G3DSA:3.10.310.10 152 309 1.7E-52 T 29-03-2018 SMALA_RS10235 ef8ddb309503fe5e499869a9401858d3 479 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 33 467 1.7E-129 T 29-03-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMALA_RS10235 ef8ddb309503fe5e499869a9401858d3 479 Gene3D G3DSA:3.40.1390.10 2 96 1.6E-30 T 29-03-2018 SMALA_RS10235 ef8ddb309503fe5e499869a9401858d3 479 SUPERFAMILY SSF63418 4 103 1.7E-22 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 SMALA_RS10235 ef8ddb309503fe5e499869a9401858d3 479 Pfam PF08245 Mur ligase middle domain 113 302 3.1E-45 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMALA_RS10235 ef8ddb309503fe5e499869a9401858d3 479 SUPERFAMILY SSF53244 325 467 2.2E-34 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 SMALA_RS10235 ef8ddb309503fe5e499869a9401858d3 479 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 4 468 32.632 T 29-03-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMALA_RS10235 ef8ddb309503fe5e499869a9401858d3 479 Pfam PF01225 Mur ligase family, catalytic domain 31 100 2.8E-13 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 SMALA_RS10235 ef8ddb309503fe5e499869a9401858d3 479 Gene3D G3DSA:3.40.1190.10 97 318 2.1E-59 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMALA_RS10235 ef8ddb309503fe5e499869a9401858d3 479 Gene3D G3DSA:3.90.190.20 322 475 5.0E-49 T 29-03-2018 SMALA_RS10235 ef8ddb309503fe5e499869a9401858d3 479 SUPERFAMILY SSF53623 107 318 1.44E-53 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMALA_RS10235 ef8ddb309503fe5e499869a9401858d3 479 Pfam PF02875 Mur ligase family, glutamate ligase domain 326 410 4.3E-20 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 SMALA_RS33575 5161ca3aa478dd5f17185a67fe728620 355 Gene3D G3DSA:3.90.1200.10 98 341 9.9E-17 T 29-03-2018 SMALA_RS33575 5161ca3aa478dd5f17185a67fe728620 355 Pfam PF01636 Phosphotransferase enzyme family 28 247 4.4E-20 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase SMALA_RS33575 5161ca3aa478dd5f17185a67fe728620 355 SUPERFAMILY SSF56112 11 321 5.1E-36 T 29-03-2018 IPR011009 Protein kinase-like domain SMALA_RS33575 5161ca3aa478dd5f17185a67fe728620 355 Gene3D G3DSA:3.30.200.20 6 97 5.7E-11 T 29-03-2018 SMALA_RS38835 09f1cb3bd43b6b5ec928930b1f7031e0 342 Gene3D G3DSA:3.40.50.1980 180 342 5.8E-38 T 29-03-2018 SMALA_RS38835 09f1cb3bd43b6b5ec928930b1f7031e0 342 Pfam PF01497 Periplasmic binding protein 74 315 8.5E-32 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 SMALA_RS38835 09f1cb3bd43b6b5ec928930b1f7031e0 342 SUPERFAMILY SSF53807 69 339 1.37E-47 T 29-03-2018 SMALA_RS38835 09f1cb3bd43b6b5ec928930b1f7031e0 342 Gene3D G3DSA:3.40.50.1980 46 179 5.3E-29 T 29-03-2018 SMALA_RS13005 95e600842965428dd3b57d1796ee50f3 97 Gene3D G3DSA:3.30.70.970 9 95 5.8E-5 T 29-03-2018 IPR009671 Regulator of ribonuclease activity B domain SMALA_RS03695 465cfe84d268b8822906ebbc1486894d 172 SUPERFAMILY SSF55729 2 164 1.19E-39 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS03695 465cfe84d268b8822906ebbc1486894d 172 Pfam PF13302 Acetyltransferase (GNAT) domain 2 141 5.5E-17 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SMALA_RS03695 465cfe84d268b8822906ebbc1486894d 172 Gene3D G3DSA:3.40.630.30 1 172 7.8E-29 T 29-03-2018 SMALA_RS41590 58573b9190210fefb84364631f305124 328 Pfam PF04199 Putative cyclase 81 260 1.7E-25 T 29-03-2018 IPR007325 Kynurenine formamidase GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 SMALA_RS41590 58573b9190210fefb84364631f305124 328 Gene3D G3DSA:3.50.30.50 56 328 6.4E-54 T 29-03-2018 SMALA_RS41590 58573b9190210fefb84364631f305124 328 SUPERFAMILY SSF102198 58 327 5.89E-30 T 29-03-2018 SMALA_RS34350 68dfb28dcb7ae204d0a10df45b31f2eb 374 Pfam PF13810 Domain of unknown function (DUF4185) 70 368 5.7E-53 T 29-03-2018 IPR025442 Domain of unknown function DUF4185 SMALA_RS34350 68dfb28dcb7ae204d0a10df45b31f2eb 374 Gene3D G3DSA:2.120.10.10 11 270 6.7E-6 T 29-03-2018 SMALA_RS34350 68dfb28dcb7ae204d0a10df45b31f2eb 374 SUPERFAMILY SSF50939 174 226 7.65E-6 T 29-03-2018 IPR011040 Sialidases KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 SMALA_RS34350 68dfb28dcb7ae204d0a10df45b31f2eb 374 SUPERFAMILY SSF50939 87 116 7.65E-6 T 29-03-2018 IPR011040 Sialidases KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 SMALA_RS06490 da95c14c4aa9f4653014e664dc66bc9d 403 SUPERFAMILY SSF53474 174 399 9.79E-27 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS06490 da95c14c4aa9f4653014e664dc66bc9d 403 SMART SM00824 Thioesterase 198 398 3.0E-70 T 29-03-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 SMALA_RS06490 da95c14c4aa9f4653014e664dc66bc9d 403 Pfam PF00975 Thioesterase domain 219 397 6.8E-15 T 29-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 SMALA_RS06490 da95c14c4aa9f4653014e664dc66bc9d 403 Gene3D G3DSA:3.40.50.1820 95 400 2.0E-11 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS06490 da95c14c4aa9f4653014e664dc66bc9d 403 Pfam PF14765 Polyketide synthase dehydratase 1 124 4.4E-15 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMALA_RS10520 a9ed539381999c7ee1416f9fb00672bf 545 Pfam PF13631 Cytochrome b(N-terminal)/b6/petB 124 297 1.5E-56 T 29-03-2018 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 SMALA_RS10520 a9ed539381999c7ee1416f9fb00672bf 545 SUPERFAMILY SSF81342 23 300 5.97E-62 T 29-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 SMALA_RS10520 a9ed539381999c7ee1416f9fb00672bf 545 Gene3D G3DSA:1.20.810.10 26 445 1.9E-102 T 29-03-2018 IPR027387 Cytochrome b/b6-like domain Reactome: R-HSA-611105 SMALA_RS32475 c167dc167cfa4f456dd4f9597dfd305b 262 Pfam PF00561 alpha/beta hydrolase fold 22 119 1.1E-14 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS32475 c167dc167cfa4f456dd4f9597dfd305b 262 SUPERFAMILY SSF53474 7 256 4.22E-56 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS32475 c167dc167cfa4f456dd4f9597dfd305b 262 Gene3D G3DSA:3.40.50.1820 1 260 1.0E-40 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS32475 c167dc167cfa4f456dd4f9597dfd305b 262 PRINTS PR00111 Alpha/beta hydrolase fold signature 46 61 4.9E-10 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS32475 c167dc167cfa4f456dd4f9597dfd305b 262 PRINTS PR00111 Alpha/beta hydrolase fold signature 104 117 4.9E-10 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS32475 c167dc167cfa4f456dd4f9597dfd305b 262 PRINTS PR00111 Alpha/beta hydrolase fold signature 90 103 4.9E-10 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS32475 c167dc167cfa4f456dd4f9597dfd305b 262 PRINTS PR00111 Alpha/beta hydrolase fold signature 202 216 4.9E-10 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS17415 d85b3436ab063f08f50f89bb2cf5af06 156 Pfam PF04892 VanZ like family 13 126 1.3E-21 T 29-03-2018 IPR006976 VanZ-like SMALA_RS38265 c17a45c4fbb50aa3dfa53ce3131c7b77 755 SUPERFAMILY SSF82866 144 336 2.09E-28 T 29-03-2018 SMALA_RS38265 c17a45c4fbb50aa3dfa53ce3131c7b77 755 Pfam PF03176 MMPL family 71 352 2.7E-44 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 SMALA_RS38265 c17a45c4fbb50aa3dfa53ce3131c7b77 755 Pfam PF03176 MMPL family 400 704 3.5E-31 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 SMALA_RS38265 c17a45c4fbb50aa3dfa53ce3131c7b77 755 Gene3D G3DSA:1.20.1640.10 85 341 4.0E-29 T 29-03-2018 SMALA_RS38265 c17a45c4fbb50aa3dfa53ce3131c7b77 755 SUPERFAMILY SSF82866 505 704 7.72E-28 T 29-03-2018 SMALA_RS38265 c17a45c4fbb50aa3dfa53ce3131c7b77 755 Gene3D G3DSA:1.20.1640.10 482 700 2.2E-28 T 29-03-2018 SMALA_RS24290 3f1fa26d1f91af3695742a191dcd27e9 249 Pfam PF10138 vWA found in TerF C terminus 48 247 3.9E-67 T 29-03-2018 IPR019303 vWA found in TerF C terminus SMALA_RS24290 3f1fa26d1f91af3695742a191dcd27e9 249 SMART SM00327 48 214 2.2E-9 T 29-03-2018 IPR002035 von Willebrand factor, type A SMALA_RS24290 3f1fa26d1f91af3695742a191dcd27e9 249 SUPERFAMILY SSF53300 48 202 8.16E-16 T 29-03-2018 IPR002035 von Willebrand factor, type A SMALA_RS24290 3f1fa26d1f91af3695742a191dcd27e9 249 Gene3D G3DSA:3.40.50.410 44 240 4.1E-17 T 29-03-2018 IPR002035 von Willebrand factor, type A SMALA_RS13985 249c5278155d872d19b6ed6a6c1d1cf2 276 Pfam PF01261 Xylose isomerase-like TIM barrel 26 221 8.9E-34 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SMALA_RS13985 249c5278155d872d19b6ed6a6c1d1cf2 276 SUPERFAMILY SSF51658 3 271 1.31E-59 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SMALA_RS13985 249c5278155d872d19b6ed6a6c1d1cf2 276 Gene3D G3DSA:3.20.20.150 1 275 4.8E-59 T 29-03-2018 SMALA_RS06475 9de1f703fc78216e5c7c53995c40305a 133 Gene3D G3DSA:3.10.450.50 1 133 6.5E-8 T 29-03-2018 SMALA_RS06475 9de1f703fc78216e5c7c53995c40305a 133 SUPERFAMILY SSF54427 3 131 5.26E-9 T 29-03-2018 IPR032710 NTF2-like domain SMALA_RS14720 43e0e19b88fa0c238b346863800becd4 374 Gene3D G3DSA:3.40.47.10 218 334 0.28 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS14720 43e0e19b88fa0c238b346863800becd4 374 Gene3D G3DSA:3.40.47.10 23 191 1.2E-16 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS14720 43e0e19b88fa0c238b346863800becd4 374 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 54 184 1.9E-8 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS14720 43e0e19b88fa0c238b346863800becd4 374 SUPERFAMILY SSF53901 29 210 1.0E-18 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS11870 4cd923be2102031432174243257e82df 436 Gene3D G3DSA:1.20.120.330 188 374 2.3E-5 T 29-03-2018 SMALA_RS11870 4cd923be2102031432174243257e82df 436 Gene3D G3DSA:1.20.120.330 33 182 0.032 T 29-03-2018 SMALA_RS19950 311d9d8aaee81684fd296d077bede32f 574 TIGRFAM TIGR02288 PaaN_2: phenylacetic acid degradation protein paaN 8 573 1.6E-280 T 29-03-2018 IPR011975 Phenylacetic acid degradation protein PaaN2 SMALA_RS19950 311d9d8aaee81684fd296d077bede32f 574 SUPERFAMILY SSF53720 83 548 4.19E-54 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMALA_RS19950 311d9d8aaee81684fd296d077bede32f 574 Gene3D G3DSA:3.40.605.10 82 334 2.5E-34 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS19950 311d9d8aaee81684fd296d077bede32f 574 Gene3D G3DSA:3.40.309.10 335 540 1.5E-21 T 29-03-2018 SMALA_RS19950 311d9d8aaee81684fd296d077bede32f 574 Pfam PF00171 Aldehyde dehydrogenase family 99 525 2.0E-28 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS42685 42831755660c6676a68eddfedd7f4824 278 Pfam PF00106 short chain dehydrogenase 21 206 1.9E-42 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS42685 42831755660c6676a68eddfedd7f4824 278 Gene3D G3DSA:3.40.50.720 15 273 5.4E-47 T 29-03-2018 SMALA_RS42685 42831755660c6676a68eddfedd7f4824 278 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 155 183 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMALA_RS42685 42831755660c6676a68eddfedd7f4824 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 20 37 7.8E-27 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS42685 42831755660c6676a68eddfedd7f4824 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 232 252 7.8E-27 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS42685 42831755660c6676a68eddfedd7f4824 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 142 158 7.8E-27 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS42685 42831755660c6676a68eddfedd7f4824 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 187 7.8E-27 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS42685 42831755660c6676a68eddfedd7f4824 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 91 102 7.8E-27 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS42685 42831755660c6676a68eddfedd7f4824 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 188 205 7.8E-27 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS42685 42831755660c6676a68eddfedd7f4824 278 SUPERFAMILY SSF51735 16 265 1.54E-49 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS02295 db84a22e73e34c6c358d2a54ba5b79bb 343 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 108 116 1.3E-16 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMALA_RS02295 db84a22e73e34c6c358d2a54ba5b79bb 343 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 268 286 1.3E-16 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMALA_RS02295 db84a22e73e34c6c358d2a54ba5b79bb 343 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 145 169 1.3E-16 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMALA_RS02295 db84a22e73e34c6c358d2a54ba5b79bb 343 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 10 32 1.3E-16 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMALA_RS02295 db84a22e73e34c6c358d2a54ba5b79bb 343 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 130 142 1.3E-16 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMALA_RS02295 db84a22e73e34c6c358d2a54ba5b79bb 343 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 9 293 4.3E-18 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS02295 db84a22e73e34c6c358d2a54ba5b79bb 343 SUPERFAMILY SSF51905 7 302 1.36E-32 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS02295 db84a22e73e34c6c358d2a54ba5b79bb 343 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 107 125 8.6E-14 T 29-03-2018 SMALA_RS02295 db84a22e73e34c6c358d2a54ba5b79bb 343 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 149 167 8.6E-14 T 29-03-2018 SMALA_RS02295 db84a22e73e34c6c358d2a54ba5b79bb 343 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 8.6E-14 T 29-03-2018 SMALA_RS02295 db84a22e73e34c6c358d2a54ba5b79bb 343 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 258 280 8.6E-14 T 29-03-2018 SMALA_RS02295 db84a22e73e34c6c358d2a54ba5b79bb 343 Gene3D G3DSA:3.50.50.60 5 132 6.7E-21 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS02295 db84a22e73e34c6c358d2a54ba5b79bb 343 Gene3D G3DSA:3.50.50.60 133 232 5.0E-17 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS07670 d26c810a109e52853acfbd508839624e 299 Pfam PF00482 Type II secretion system (T2SS), protein F 163 290 4.1E-9 T 29-03-2018 IPR018076 Type II secretion system F domain SMALA_RS28845 dbca27675451aba52747a46bbd9de633 215 Gene3D G3DSA:1.10.3720.10 6 212 1.9E-37 T 29-03-2018 SMALA_RS28845 dbca27675451aba52747a46bbd9de633 215 SUPERFAMILY SSF161098 10 203 2.35E-36 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS28845 dbca27675451aba52747a46bbd9de633 215 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 30 212 2.1E-13 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS28845 dbca27675451aba52747a46bbd9de633 215 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 8 106 8.6E-19 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 SMALA_RS02995 f66f3b36e86b0ad54673099beefb2051 80 Pfam PF01084 Ribosomal protein S18 25 75 2.6E-25 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS02995 f66f3b36e86b0ad54673099beefb2051 80 Gene3D G3DSA:4.10.640.10 2 80 5.0E-30 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS02995 f66f3b36e86b0ad54673099beefb2051 80 PRINTS PR00974 Ribosomal protein S18 family signature 35 45 5.1E-18 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS02995 f66f3b36e86b0ad54673099beefb2051 80 PRINTS PR00974 Ribosomal protein S18 family signature 67 77 5.1E-18 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS02995 f66f3b36e86b0ad54673099beefb2051 80 PRINTS PR00974 Ribosomal protein S18 family signature 53 67 5.1E-18 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS02995 f66f3b36e86b0ad54673099beefb2051 80 PRINTS PR00974 Ribosomal protein S18 family signature 45 52 5.1E-18 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS02995 f66f3b36e86b0ad54673099beefb2051 80 SUPERFAMILY SSF46911 7 78 4.45E-27 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS02995 f66f3b36e86b0ad54673099beefb2051 80 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 5 80 20.067 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS02995 f66f3b36e86b0ad54673099beefb2051 80 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 27 77 4.0E-10 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS02995 f66f3b36e86b0ad54673099beefb2051 80 ProSitePatterns PS00057 Ribosomal protein S18 signature. 28 51 - T 29-03-2018 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS02995 f66f3b36e86b0ad54673099beefb2051 80 TIGRFAM TIGR00165 S18: ribosomal protein bS18 15 77 4.9E-24 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS41090 76e6fe010a0b70e599bfabde6f72f9a8 392 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 334 343 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMALA_RS41090 76e6fe010a0b70e599bfabde6f72f9a8 392 Gene3D G3DSA:1.10.630.10 2 391 7.6E-59 T 29-03-2018 SMALA_RS41090 76e6fe010a0b70e599bfabde6f72f9a8 392 Pfam PF00067 Cytochrome P450 259 358 8.4E-22 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS41090 76e6fe010a0b70e599bfabde6f72f9a8 392 SUPERFAMILY SSF48264 15 381 1.18E-75 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS41090 76e6fe010a0b70e599bfabde6f72f9a8 392 PRINTS PR00359 B-class P450 signature 266 277 7.0E-36 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS41090 76e6fe010a0b70e599bfabde6f72f9a8 392 PRINTS PR00359 B-class P450 signature 311 326 7.0E-36 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS41090 76e6fe010a0b70e599bfabde6f72f9a8 392 PRINTS PR00359 B-class P450 signature 129 145 7.0E-36 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS41090 76e6fe010a0b70e599bfabde6f72f9a8 392 PRINTS PR00359 B-class P450 signature 283 310 7.0E-36 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS41090 76e6fe010a0b70e599bfabde6f72f9a8 392 PRINTS PR00359 B-class P450 signature 341 352 7.0E-36 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS41090 76e6fe010a0b70e599bfabde6f72f9a8 392 PRINTS PR00359 B-class P450 signature 83 94 7.0E-36 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS41090 76e6fe010a0b70e599bfabde6f72f9a8 392 PRINTS PR00359 B-class P450 signature 146 161 7.0E-36 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS41090 76e6fe010a0b70e599bfabde6f72f9a8 392 PRINTS PR00359 B-class P450 signature 332 341 7.0E-36 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS41000 ccb9d4d62188dfbdc8c8fd1a54d969d9 241 SUPERFAMILY SSF52833 7 205 2.37E-27 T 29-03-2018 IPR012336 Thioredoxin-like fold SMALA_RS41000 ccb9d4d62188dfbdc8c8fd1a54d969d9 241 Pfam PF01323 DSBA-like thioredoxin domain 7 200 7.0E-17 T 29-03-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 SMALA_RS41000 ccb9d4d62188dfbdc8c8fd1a54d969d9 241 PIRSF PIRSF006386 1 212 1.8E-38 T 29-03-2018 IPR014440 HCCA isomerase/glutathione S-transferase kappa Reactome: R-HSA-156590 SMALA_RS41000 ccb9d4d62188dfbdc8c8fd1a54d969d9 241 Gene3D G3DSA:3.40.30.10 6 201 2.6E-31 T 29-03-2018 SMALA_RS32165 911cf8e03d0a006a3275f01cdf1c378e 84 Pfam PF04149 Domain of unknown function (DUF397) 23 75 1.4E-12 T 29-03-2018 IPR007278 Domain of unknown function DUF397 SMALA_RS33185 040683593a491bb9b1f3d70469306296 221 SUPERFAMILY SSF53597 83 218 1.2E-24 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 SMALA_RS33185 040683593a491bb9b1f3d70469306296 221 Pfam PF01872 RibD C-terminal domain 4 213 2.1E-18 T 29-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 SMALA_RS33185 040683593a491bb9b1f3d70469306296 221 Gene3D G3DSA:3.40.430.10 3 218 1.7E-40 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 SMALA_RS40245 ef2eccbe3d400626fecacf2b7c993719 314 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 181 298 9.6E-21 T 29-03-2018 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 SMALA_RS40245 ef2eccbe3d400626fecacf2b7c993719 314 Gene3D G3DSA:1.10.1040.10 180 314 4.4E-24 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMALA_RS40245 ef2eccbe3d400626fecacf2b7c993719 314 SUPERFAMILY SSF48179 181 304 1.5E-21 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMALA_RS40245 ef2eccbe3d400626fecacf2b7c993719 314 Pfam PF02558 Ketopantoate reductase PanE/ApbA 4 154 4.8E-33 T 29-03-2018 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 SMALA_RS40245 ef2eccbe3d400626fecacf2b7c993719 314 SUPERFAMILY SSF51735 3 182 1.13E-10 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS40245 ef2eccbe3d400626fecacf2b7c993719 314 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 3 295 7.1E-57 T 29-03-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0015940|GO:0016491|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 SMALA_RS40245 ef2eccbe3d400626fecacf2b7c993719 314 Gene3D G3DSA:3.40.50.720 1 179 5.2E-26 T 29-03-2018 SMALA_RS06565 5d1fc8a598f92e4d80f1c42f71a4d093 185 SUPERFAMILY SSF55811 24 167 9.88E-17 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMALA_RS06565 5d1fc8a598f92e4d80f1c42f71a4d093 185 Pfam PF00293 NUDIX domain 40 153 7.4E-9 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SMALA_RS06565 5d1fc8a598f92e4d80f1c42f71a4d093 185 Gene3D G3DSA:3.90.79.10 6 183 1.9E-17 T 29-03-2018 SMALA_RS29215 b14364935192cbc49542d8a019a3a936 175 SUPERFAMILY SSF51283 4 147 3.66E-42 T 29-03-2018 IPR029054 dUTPase-like SMALA_RS29215 b14364935192cbc49542d8a019a3a936 175 Hamap MF_00116 Deoxyuridine 5'-triphosphate nucleotidohydrolase [dut]. 6 148 30.932 T 29-03-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|Reactome: R-HSA-499943 SMALA_RS29215 b14364935192cbc49542d8a019a3a936 175 Gene3D G3DSA:2.70.40.10 1 111 1.0E-39 T 29-03-2018 SMALA_RS29215 b14364935192cbc49542d8a019a3a936 175 Pfam PF00692 dUTPase 17 147 9.5E-29 T 29-03-2018 IPR029054 dUTPase-like SMALA_RS29215 b14364935192cbc49542d8a019a3a936 175 Gene3D G3DSA:2.70.40.10 112 147 4.5E-11 T 29-03-2018 SMALA_RS29215 b14364935192cbc49542d8a019a3a936 175 TIGRFAM TIGR00576 dut: dUTP diphosphatase 9 147 2.1E-49 T 29-03-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|Reactome: R-HSA-499943 SMALA_RS24345 81241b7c2030fb85e167b02dd84360bd 199 Pfam PF04978 Protein of unknown function (DUF664) 10 158 2.2E-43 T 29-03-2018 IPR007061 Protein of unknown function DUF664 SMALA_RS24345 81241b7c2030fb85e167b02dd84360bd 199 SUPERFAMILY SSF109854 8 157 7.33E-36 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes SMALA_RS24345 81241b7c2030fb85e167b02dd84360bd 199 Gene3D G3DSA:1.20.120.450 4 173 7.9E-30 T 29-03-2018 SMALA_RS38800 0f5540c3a93fbdfeaca9ff7c24d84b87 237 SUPERFAMILY SSF46689 10 89 9.98E-18 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS38800 0f5540c3a93fbdfeaca9ff7c24d84b87 237 Gene3D G3DSA:1.10.357.10 64 211 1.1E-22 T 29-03-2018 SMALA_RS38800 0f5540c3a93fbdfeaca9ff7c24d84b87 237 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 35 1.3E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS38800 0f5540c3a93fbdfeaca9ff7c24d84b87 237 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 66 1.3E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS38800 0f5540c3a93fbdfeaca9ff7c24d84b87 237 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 65 3.6E-15 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS38800 0f5540c3a93fbdfeaca9ff7c24d84b87 237 Gene3D G3DSA:1.10.10.60 3 63 5.1E-19 T 29-03-2018 SMALA_RS38800 0f5540c3a93fbdfeaca9ff7c24d84b87 237 ProSitePatterns PS01081 TetR-type HTH domain signature. 34 65 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site SMALA_RS22240 46ba5a49a6fd4beec1156a4298830d8e 360 Gene3D G3DSA:3.40.50.970 101 262 2.6E-40 T 29-03-2018 SMALA_RS22240 46ba5a49a6fd4beec1156a4298830d8e 360 Gene3D G3DSA:3.40.50.970 15 100 6.2E-23 T 29-03-2018 SMALA_RS22240 46ba5a49a6fd4beec1156a4298830d8e 360 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 72 219 2.2E-29 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 SMALA_RS22240 46ba5a49a6fd4beec1156a4298830d8e 360 SUPERFAMILY SSF52518 29 359 1.48E-85 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold SMALA_RS20740 9086bb19d89b060429db12b7753039d1 271 SUPERFAMILY SSF74650 6 248 1.57E-41 T 29-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 SMALA_RS20740 9086bb19d89b060429db12b7753039d1 271 Gene3D G3DSA:2.70.98.10 1 270 4.2E-46 T 29-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 SMALA_RS20740 9086bb19d89b060429db12b7753039d1 271 Pfam PF01263 Aldose 1-epimerase 24 186 2.3E-20 T 29-03-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 SMALA_RS18525 2303996e830c220db944362e97f039df 142 Pfam PF13581 Histidine kinase-like ATPase domain 8 133 3.5E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS18525 2303996e830c220db944362e97f039df 142 Gene3D G3DSA:3.30.565.10 1 140 4.8E-11 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS40160 f343e4f98fd04325a70ee722882781de 140 Pfam PF02566 OsmC-like protein 38 127 1.7E-13 T 29-03-2018 IPR003718 OsmC/Ohr family SMALA_RS40160 f343e4f98fd04325a70ee722882781de 140 Gene3D G3DSA:3.30.300.20 2 140 2.4E-18 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta SMALA_RS40160 f343e4f98fd04325a70ee722882781de 140 SUPERFAMILY SSF82784 15 130 3.27E-18 T 29-03-2018 IPR003718 OsmC/Ohr family SMALA_RS18925 cb4636297c7bdf47547c1c715b3fb9b0 224 SUPERFAMILY SSF52172 2 136 7.54E-22 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS18925 cb4636297c7bdf47547c1c715b3fb9b0 224 SMART SM00448 1 120 7.7E-15 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS18925 cb4636297c7bdf47547c1c715b3fb9b0 224 Pfam PF00072 Response regulator receiver domain 3 108 3.4E-15 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS18925 cb4636297c7bdf47547c1c715b3fb9b0 224 SUPERFAMILY SSF46894 137 194 2.18E-15 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS18925 cb4636297c7bdf47547c1c715b3fb9b0 224 SMART SM00421 147 209 1.9E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS18925 cb4636297c7bdf47547c1c715b3fb9b0 224 Gene3D G3DSA:1.10.10.10 149 215 4.4E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS18925 cb4636297c7bdf47547c1c715b3fb9b0 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 180 2.0E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS18925 cb4636297c7bdf47547c1c715b3fb9b0 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 192 2.0E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS18925 cb4636297c7bdf47547c1c715b3fb9b0 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 164 2.0E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS18925 cb4636297c7bdf47547c1c715b3fb9b0 224 Pfam PF00196 Bacterial regulatory proteins, luxR family 148 194 8.0E-15 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS18925 cb4636297c7bdf47547c1c715b3fb9b0 224 Gene3D G3DSA:3.40.50.2300 1 147 3.7E-29 T 29-03-2018 SMALA_RS04565 55eb058602662bc786187a70d266c0b7 218 SUPERFAMILY SSF109854 2 151 3.05E-10 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes SMALA_RS04565 55eb058602662bc786187a70d266c0b7 218 Gene3D G3DSA:1.20.120.450 1 154 5.7E-21 T 29-03-2018 SMALA_RS04565 55eb058602662bc786187a70d266c0b7 218 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 6 149 6.1E-20 T 29-03-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 SMALA_RS41815 2be4bca7a79e837dc7a3c2315c185577 349 Gene3D G3DSA:2.120.10.30 26 334 8.5E-24 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like SMALA_RS41815 2be4bca7a79e837dc7a3c2315c185577 349 SUPERFAMILY SSF63829 23 340 1.26E-39 T 29-03-2018 SMALA_RS41815 2be4bca7a79e837dc7a3c2315c185577 349 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 68 263 5.7E-15 T 29-03-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region SMALA_RS35475 14035bf2d862c5cf494a409299da2fea 253 Gene3D G3DSA:3.40.50.1360 73 240 7.7E-32 T 29-03-2018 SMALA_RS35475 14035bf2d862c5cf494a409299da2fea 253 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 1.2E-7 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMALA_RS35475 14035bf2d862c5cf494a409299da2fea 253 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 1.2E-7 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMALA_RS35475 14035bf2d862c5cf494a409299da2fea 253 Pfam PF08220 DeoR-like helix-turn-helix domain 6 59 2.4E-15 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMALA_RS35475 14035bf2d862c5cf494a409299da2fea 253 Gene3D G3DSA:1.10.10.10 1 58 2.0E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS35475 14035bf2d862c5cf494a409299da2fea 253 Pfam PF00455 DeoR C terminal sensor domain 77 232 4.7E-42 T 29-03-2018 IPR014036 DeoR C-terminal sensor domain SMALA_RS35475 14035bf2d862c5cf494a409299da2fea 253 SMART SM01134 73 234 6.9E-58 T 29-03-2018 SMALA_RS35475 14035bf2d862c5cf494a409299da2fea 253 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 29-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 SMALA_RS35475 14035bf2d862c5cf494a409299da2fea 253 SMART SM00420 6 58 4.3E-15 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMALA_RS35475 14035bf2d862c5cf494a409299da2fea 253 SUPERFAMILY SSF100950 79 233 2.01E-25 T 29-03-2018 SMALA_RS35475 14035bf2d862c5cf494a409299da2fea 253 SUPERFAMILY SSF46785 4 68 1.19E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS27010 90e0f39078ce6ee0e9c37ad6241d76e2 351 Gene3D G3DSA:3.20.20.30 1 351 5.4E-90 T 29-03-2018 SMALA_RS27010 90e0f39078ce6ee0e9c37ad6241d76e2 351 Pfam PF00296 Luciferase-like monooxygenase 1 320 7.2E-54 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS27010 90e0f39078ce6ee0e9c37ad6241d76e2 351 SUPERFAMILY SSF51679 1 351 2.62E-69 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS04715 b9681db6a0ab1cecd3319712a9410902 479 Pfam PF13416 Bacterial extracellular solute-binding protein 75 399 9.4E-28 T 29-03-2018 SMALA_RS04715 b9681db6a0ab1cecd3319712a9410902 479 Gene3D G3DSA:3.40.190.10 51 245 1.2E-28 T 29-03-2018 SMALA_RS04715 b9681db6a0ab1cecd3319712a9410902 479 Gene3D G3DSA:3.40.190.10 269 419 1.2E-4 T 29-03-2018 SMALA_RS04715 b9681db6a0ab1cecd3319712a9410902 479 SUPERFAMILY SSF53850 46 431 2.22E-45 T 29-03-2018 SMALA_RS25425 b3a79e1d379e7f40456ab44f449ab02a 94 SUPERFAMILY SSF143120 3 70 4.58E-15 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM SMALA_RS25425 b3a79e1d379e7f40456ab44f449ab02a 94 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 2 54 3.2E-11 T 29-03-2018 SMALA_RS25425 b3a79e1d379e7f40456ab44f449ab02a 94 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 2 64 4.3E-12 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM SMALA_RS25425 b3a79e1d379e7f40456ab44f449ab02a 94 Gene3D G3DSA:3.40.1620.10 2 38 8.6E-13 T 29-03-2018 SMALA_RS41745 824b13578b016263fd49387e20735229 155 PRINTS PR00502 NUDIX hydrolase family signature 45 60 1.7E-6 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMALA_RS41745 824b13578b016263fd49387e20735229 155 PRINTS PR00502 NUDIX hydrolase family signature 31 45 1.7E-6 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMALA_RS41745 824b13578b016263fd49387e20735229 155 SUPERFAMILY SSF55811 3 123 6.91E-28 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMALA_RS41745 824b13578b016263fd49387e20735229 155 Pfam PF00293 NUDIX domain 4 119 1.6E-16 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SMALA_RS41745 824b13578b016263fd49387e20735229 155 Gene3D G3DSA:3.90.79.10 1 138 2.7E-26 T 29-03-2018 SMALA_RS41745 824b13578b016263fd49387e20735229 155 ProSitePatterns PS00893 Nudix box signature. 36 57 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 SMALA_RS25455 28b7854e09f004cf733a5264aa67b2c6 450 Gene3D G3DSA:1.10.510.10 227 351 3.8E-6 T 29-03-2018 SMALA_RS25455 28b7854e09f004cf733a5264aa67b2c6 450 SUPERFAMILY SSF56112 57 349 1.37E-12 T 29-03-2018 IPR011009 Protein kinase-like domain SMALA_RS25455 28b7854e09f004cf733a5264aa67b2c6 450 Gene3D G3DSA:3.30.200.20 49 209 1.7E-6 T 29-03-2018 SMALA_RS08330 ee894c022fe27a8d925942a2e612040b 270 Gene3D G3DSA:3.90.550.10 10 264 3.8E-30 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS08330 ee894c022fe27a8d925942a2e612040b 270 SUPERFAMILY SSF53448 23 248 1.97E-39 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS08330 ee894c022fe27a8d925942a2e612040b 270 Pfam PF00535 Glycosyl transferase family 2 35 176 3.0E-20 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 SMALA_RS11910 7476f75bac5d67a56e9fac498eb0a417 387 Gene3D G3DSA:2.60.60.30 15 178 1.3E-40 T 29-03-2018 SMALA_RS11910 7476f75bac5d67a56e9fac498eb0a417 387 Pfam PF02342 TerD domain 1 179 6.1E-41 T 29-03-2018 IPR003325 TerD domain GO:0006950 SMALA_RS10530 9a4eff2df28518e8011da21f34dd073a 269 PIRSF PIRSF000007 1 263 3.8E-120 T 29-03-2018 IPR009152 Cytochrome bc1 complex, cytochrome c subunit GO:0005506|GO:0009055|GO:0016021|GO:0020037 SMALA_RS10530 9a4eff2df28518e8011da21f34dd073a 269 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 48 122 3.1E-9 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 SMALA_RS10530 9a4eff2df28518e8011da21f34dd073a 269 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 142 216 1.5E-12 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 SMALA_RS10530 9a4eff2df28518e8011da21f34dd073a 269 SUPERFAMILY SSF46626 124 218 2.51E-25 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 SMALA_RS10530 9a4eff2df28518e8011da21f34dd073a 269 Gene3D G3DSA:1.10.760.10 28 134 6.7E-17 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 SMALA_RS10530 9a4eff2df28518e8011da21f34dd073a 269 Gene3D G3DSA:1.10.760.10 135 229 8.0E-17 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 SMALA_RS10530 9a4eff2df28518e8011da21f34dd073a 269 SUPERFAMILY SSF46626 13 130 5.73E-19 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 SMALA_RS28170 37d49b33c6b0facadebbb50b8861d8e3 260 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 11 203 4.2E-41 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SMALA_RS28170 37d49b33c6b0facadebbb50b8861d8e3 260 Gene3D G3DSA:2.10.109.10 21 216 4.2E-49 T 29-03-2018 SMALA_RS28170 37d49b33c6b0facadebbb50b8861d8e3 260 ProSitePatterns PS00761 Signal peptidases I signature 3. 162 175 - T 29-03-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 SMALA_RS28170 37d49b33c6b0facadebbb50b8861d8e3 260 Pfam PF00717 Peptidase S24-like 32 74 9.7E-12 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C SMALA_RS28170 37d49b33c6b0facadebbb50b8861d8e3 260 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 157 176 7.0E-20 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SMALA_RS28170 37d49b33c6b0facadebbb50b8861d8e3 260 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 108 120 7.0E-20 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SMALA_RS28170 37d49b33c6b0facadebbb50b8861d8e3 260 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 25 41 7.0E-20 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SMALA_RS28170 37d49b33c6b0facadebbb50b8861d8e3 260 SUPERFAMILY SSF51306 24 72 9.94E-50 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C SMALA_RS28170 37d49b33c6b0facadebbb50b8861d8e3 260 SUPERFAMILY SSF51306 103 208 9.94E-50 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C SMALA_RS41025 a5c0f0dde4901c547ab6296b1c176977 254 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 190 0.0054 T 29-03-2018 SMALA_RS41025 a5c0f0dde4901c547ab6296b1c176977 254 Gene3D G3DSA:3.40.50.720 2 251 1.4E-51 T 29-03-2018 SMALA_RS41025 a5c0f0dde4901c547ab6296b1c176977 254 SUPERFAMILY SSF51735 5 247 5.43E-57 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS41025 a5c0f0dde4901c547ab6296b1c176977 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.1E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS41025 a5c0f0dde4901c547ab6296b1c176977 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 1.1E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS41025 a5c0f0dde4901c547ab6296b1c176977 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 1.1E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS41025 a5c0f0dde4901c547ab6296b1c176977 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.1E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS41025 a5c0f0dde4901c547ab6296b1c176977 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 1.1E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS41025 a5c0f0dde4901c547ab6296b1c176977 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 1.1E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS41025 a5c0f0dde4901c547ab6296b1c176977 254 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 9 246 6.3E-43 T 29-03-2018 SMALA_RS23045 294e5c7a055e59a71440a7043c357c47 461 SUPERFAMILY SSF47203 373 454 6.94E-16 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMALA_RS23045 294e5c7a055e59a71440a7043c357c47 461 SUPERFAMILY SSF47203 244 318 6.94E-16 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMALA_RS23045 294e5c7a055e59a71440a7043c357c47 461 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 131 1.0E-13 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS23045 294e5c7a055e59a71440a7043c357c47 461 Gene3D G3DSA:1.10.540.10 1 134 4.0E-25 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS23045 294e5c7a055e59a71440a7043c357c47 461 SUPERFAMILY SSF56645 2 254 2.49E-58 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMALA_RS23045 294e5c7a055e59a71440a7043c357c47 461 Gene3D G3DSA:1.20.140.10 242 461 1.7E-37 T 29-03-2018 SMALA_RS23045 294e5c7a055e59a71440a7043c357c47 461 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 244 315 4.8E-5 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMALA_RS23045 294e5c7a055e59a71440a7043c357c47 461 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 372 453 2.2E-12 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMALA_RS23045 294e5c7a055e59a71440a7043c357c47 461 Gene3D G3DSA:2.40.110.10 135 241 6.9E-30 T 29-03-2018 SMALA_RS23045 294e5c7a055e59a71440a7043c357c47 461 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 135 230 1.2E-21 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 SMALA_RS29120 2ae8cb489978dc6e9b98d293888a5175 93 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 82 4.6E-25 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like SMALA_RS29120 2ae8cb489978dc6e9b98d293888a5175 93 Pfam PF00381 PTS HPr component phosphorylation site 3 83 3.4E-22 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like SMALA_RS29120 2ae8cb489978dc6e9b98d293888a5175 93 Gene3D G3DSA:3.30.1340.10 1 86 5.7E-27 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like SMALA_RS29120 2ae8cb489978dc6e9b98d293888a5175 93 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 29-03-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site SMALA_RS29120 2ae8cb489978dc6e9b98d293888a5175 93 SUPERFAMILY SSF55594 1 88 8.5E-20 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like SMALA_RS29120 2ae8cb489978dc6e9b98d293888a5175 93 PRINTS PR00107 Phosphocarrier protein signature 13 29 5.3E-11 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like SMALA_RS29120 2ae8cb489978dc6e9b98d293888a5175 93 PRINTS PR00107 Phosphocarrier protein signature 54 71 5.3E-11 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like SMALA_RS29120 2ae8cb489978dc6e9b98d293888a5175 93 PRINTS PR00107 Phosphocarrier protein signature 39 54 5.3E-11 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like SMALA_RS40690 7275bf9294fd838445b054b4218acc9a 296 Gene3D G3DSA:3.90.850.10 47 296 6.2E-75 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 SMALA_RS40690 7275bf9294fd838445b054b4218acc9a 296 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 81 295 7.0E-68 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 SMALA_RS40690 7275bf9294fd838445b054b4218acc9a 296 SUPERFAMILY SSF56529 64 295 1.7E-66 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 SMALA_RS02300 41f448556259c97ab08702d265ee452f 316 Gene3D G3DSA:3.30.300.50 7 125 4.5E-9 T 29-03-2018 IPR035070 Streptogrisin prodomain SMALA_RS02300 41f448556259c97ab08702d265ee452f 316 Gene3D G3DSA:2.40.10.10 216 303 6.0E-24 T 29-03-2018 SMALA_RS02300 41f448556259c97ab08702d265ee452f 316 Gene3D G3DSA:2.40.10.10 131 215 9.2E-20 T 29-03-2018 SMALA_RS02300 41f448556259c97ab08702d265ee452f 316 Pfam PF00089 Trypsin 156 308 1.5E-9 T 29-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 SMALA_RS02300 41f448556259c97ab08702d265ee452f 316 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 160 165 - T 29-03-2018 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 SMALA_RS02300 41f448556259c97ab08702d265ee452f 316 Pfam PF02983 Alpha-lytic protease prodomain 73 112 6.9E-5 T 29-03-2018 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 SMALA_RS02300 41f448556259c97ab08702d265ee452f 316 SUPERFAMILY SSF50494 140 309 1.82E-39 T 29-03-2018 IPR009003 Peptidase S1, PA clan SMALA_RS02300 41f448556259c97ab08702d265ee452f 316 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 281 295 4.0E-44 T 29-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMALA_RS02300 41f448556259c97ab08702d265ee452f 316 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 237 254 4.0E-44 T 29-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMALA_RS02300 41f448556259c97ab08702d265ee452f 316 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 257 280 4.0E-44 T 29-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMALA_RS02300 41f448556259c97ab08702d265ee452f 316 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 216 236 4.0E-44 T 29-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMALA_RS02300 41f448556259c97ab08702d265ee452f 316 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 158 172 4.0E-44 T 29-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMALA_RS02300 41f448556259c97ab08702d265ee452f 316 PIRSF PIRSF001134 2 316 8.1E-83 T 29-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMALA_RS02300 41f448556259c97ab08702d265ee452f 316 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 266 277 - T 29-03-2018 IPR033116 Serine proteases, trypsin family, serine active site SMALA_RS40075 24cf92456ffc132567cf2b7aa88c64c2 370 Gene3D G3DSA:3.20.20.150 82 369 2.2E-40 T 29-03-2018 SMALA_RS40075 24cf92456ffc132567cf2b7aa88c64c2 370 SUPERFAMILY SSF51658 93 366 2.35E-35 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SMALA_RS40075 24cf92456ffc132567cf2b7aa88c64c2 370 Pfam PF01261 Xylose isomerase-like TIM barrel 103 303 2.1E-22 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SMALA_RS12075 69290ca82c56da33a3839b7ede4b5974 409 SUPERFAMILY SSF103473 13 379 2.62E-27 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS12075 69290ca82c56da33a3839b7ede4b5974 409 Gene3D G3DSA:1.20.1250.20 200 393 1.2E-12 T 29-03-2018 SMALA_RS12075 69290ca82c56da33a3839b7ede4b5974 409 Pfam PF07690 Major Facilitator Superfamily 242 396 2.2E-8 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS12075 69290ca82c56da33a3839b7ede4b5974 409 Gene3D G3DSA:1.20.1250.20 1 198 3.1E-15 T 29-03-2018 SMALA_RS05010 31658bc585fc310dde8cf9bafabed7ec 339 Gene3D G3DSA:3.20.20.30 3 334 2.1E-56 T 29-03-2018 SMALA_RS05010 31658bc585fc310dde8cf9bafabed7ec 339 SUPERFAMILY SSF51679 14 328 4.19E-55 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS05010 31658bc585fc310dde8cf9bafabed7ec 339 Pfam PF00296 Luciferase-like monooxygenase 29 293 2.2E-31 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS30405 31de3a2f8808b436041c5c63bce86a86 267 Pfam PF01048 Phosphorylase superfamily 89 257 4.7E-26 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 SMALA_RS30405 31de3a2f8808b436041c5c63bce86a86 267 Gene3D G3DSA:3.40.50.1580 19 262 5.1E-31 T 29-03-2018 SMALA_RS30405 31de3a2f8808b436041c5c63bce86a86 267 SUPERFAMILY SSF53167 31 256 1.05E-41 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 SMALA_RS22420 cc3be7a981550e69c76ff237c093dfba 95 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 42 92 4.7E-18 T 29-03-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 SMALA_RS22420 cc3be7a981550e69c76ff237c093dfba 95 ProSitePatterns PS01067 Protein secE/sec61-gamma signature. 42 70 - T 29-03-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 SMALA_RS22420 cc3be7a981550e69c76ff237c093dfba 95 Hamap MF_00422 Protein translocase subunit SecE [secE]. 37 92 12.954 T 29-03-2018 IPR022943 Preprotein translocase subunit SecE Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 SMALA_RS22420 cc3be7a981550e69c76ff237c093dfba 95 Gene3D G3DSA:1.20.5.1030 39 90 3.5E-19 T 29-03-2018 SMALA_RS22420 cc3be7a981550e69c76ff237c093dfba 95 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 41 95 1.5E-21 T 29-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 SMALA_RS41680 842d1db7f6916955a31c2e3f10f323fb 713 Pfam PF06202 Amylo-alpha-1,6-glucosidase 318 676 1.4E-5 T 29-03-2018 IPR032790 Glycogen debranching enzyme, C-terminal KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-6798695|Reactome: R-HSA-70221 SMALA_RS41680 842d1db7f6916955a31c2e3f10f323fb 713 Pfam PF14742 N-terminal domain of (some) glycogen debranching enzymes 71 249 2.8E-19 T 29-03-2018 IPR032856 Putative glycogen debranching enzyme, N-terminal SMALA_RS41680 842d1db7f6916955a31c2e3f10f323fb 713 Gene3D G3DSA:1.50.10.10 284 468 1.0E-20 T 29-03-2018 SMALA_RS41680 842d1db7f6916955a31c2e3f10f323fb 713 SUPERFAMILY SSF48208 268 684 1.93E-56 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 SMALA_RS41680 842d1db7f6916955a31c2e3f10f323fb 713 Gene3D G3DSA:1.50.10.10 469 700 1.1E-33 T 29-03-2018 SMALA_RS16585 d317fc76b787e6b799b245eeb74f4540 334 SUPERFAMILY SSF50494 134 311 4.05E-15 T 29-03-2018 IPR009003 Peptidase S1, PA clan SMALA_RS16585 d317fc76b787e6b799b245eeb74f4540 334 Gene3D G3DSA:2.40.10.10 231 334 1.7E-17 T 29-03-2018 SMALA_RS16585 d317fc76b787e6b799b245eeb74f4540 334 Gene3D G3DSA:2.40.10.10 122 230 5.8E-10 T 29-03-2018 SMALA_RS31925 707c2c6eeb9db33d19ff69b8c9bfcbb4 201 Pfam PF06718 Protein of unknown function (DUF1203) 76 200 1.8E-34 T 29-03-2018 IPR009593 Protein of unknown function DUF1203 SMALA_RS31925 707c2c6eeb9db33d19ff69b8c9bfcbb4 201 PIRSF PIRSF034110 36 201 1.3E-31 T 29-03-2018 IPR009593 Protein of unknown function DUF1203 SMALA_RS21330 8b949a0db42096876965a09c70e07283 134 Pfam PF02583 Metal-sensitive transcriptional repressor 41 129 4.7E-29 T 29-03-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 SMALA_RS36130 b6524e85c5502a0adef76f40a2a4b9ee 395 SUPERFAMILY SSF56645 2 242 1.57E-59 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMALA_RS36130 b6524e85c5502a0adef76f40a2a4b9ee 395 Gene3D G3DSA:1.20.140.10 225 395 6.8E-44 T 29-03-2018 SMALA_RS36130 b6524e85c5502a0adef76f40a2a4b9ee 395 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 231 388 1.4E-22 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMALA_RS36130 b6524e85c5502a0adef76f40a2a4b9ee 395 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 120 1.3E-19 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS36130 b6524e85c5502a0adef76f40a2a4b9ee 395 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 125 217 1.9E-15 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 SMALA_RS36130 b6524e85c5502a0adef76f40a2a4b9ee 395 SUPERFAMILY SSF47203 231 392 2.42E-23 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMALA_RS36130 b6524e85c5502a0adef76f40a2a4b9ee 395 Gene3D G3DSA:2.40.110.10 120 224 1.5E-25 T 29-03-2018 SMALA_RS36130 b6524e85c5502a0adef76f40a2a4b9ee 395 Gene3D G3DSA:1.10.540.10 2 119 5.8E-26 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS42390 68dcba0d6b0c227adf1ddcad4c1948e5 135 Gene3D G3DSA:3.40.50.720 2 130 7.6E-19 T 29-03-2018 SMALA_RS42390 68dcba0d6b0c227adf1ddcad4c1948e5 135 Pfam PF00106 short chain dehydrogenase 8 102 4.0E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS42390 68dcba0d6b0c227adf1ddcad4c1948e5 135 SUPERFAMILY SSF51735 6 117 6.33E-20 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS10890 597a204343a3314d381d499f4c3ed64a 282 Pfam PF14378 PAP2 superfamily 78 259 1.8E-44 T 29-03-2018 IPR026841 Inositolphosphotransferase Aur1/Ipt1 SMALA_RS01640 01813d6a7f667eb3a530905c3f7118e9 330 SUPERFAMILY SSF53474 152 327 1.22E-42 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS01640 01813d6a7f667eb3a530905c3f7118e9 330 TIGRFAM TIGR01840 esterase_phb: esterase, PHB depolymerase family 70 277 4.9E-42 T 29-03-2018 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 SMALA_RS01640 01813d6a7f667eb3a530905c3f7118e9 330 Pfam PF10503 Esterase PHB depolymerase 73 259 1.2E-22 T 29-03-2018 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 SMALA_RS01640 01813d6a7f667eb3a530905c3f7118e9 330 Gene3D G3DSA:3.40.50.1820 46 324 9.9E-28 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS01640 01813d6a7f667eb3a530905c3f7118e9 330 SUPERFAMILY SSF53474 48 128 1.38E-11 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS28445 a95deda672152d609415c470b7e96f51 304 Gene3D G3DSA:1.10.510.10 169 271 5.7E-7 T 29-03-2018 SMALA_RS28445 a95deda672152d609415c470b7e96f51 304 SUPERFAMILY SSF56112 27 284 1.26E-19 T 29-03-2018 IPR011009 Protein kinase-like domain SMALA_RS28445 a95deda672152d609415c470b7e96f51 304 Pfam PF04655 Aminoglycoside/hydroxyurea antibiotic resistance kinase 40 287 8.9E-54 T 29-03-2018 IPR006748 Aminoglycoside/hydroxyurea antibiotic resistance kinase GO:0006468|GO:0016773|GO:0019748 SMALA_RS08865 f42d8df42401d82d26ed06d3e2a04949 267 ProDom PD040491 SCO1799 RV1486C/MT1533 MB1522C CGL1536 ML1804 MAV321 22 252 1.0E-64 T 29-03-2018 SMALA_RS10865 cfec18ccee697d0e13a594c055ce6698 276 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 83 269 6.2E-19 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS10865 cfec18ccee697d0e13a594c055ce6698 276 Gene3D G3DSA:1.10.3720.10 1 263 2.3E-45 T 29-03-2018 SMALA_RS10865 cfec18ccee697d0e13a594c055ce6698 276 SUPERFAMILY SSF161098 5 275 1.64E-69 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS11905 bade7ee61b4248f01701f245c0d9f49f 395 Gene3D G3DSA:3.20.20.360 19 344 1.2E-42 T 29-03-2018 SMALA_RS11905 bade7ee61b4248f01701f245c0d9f49f 395 SUPERFAMILY SSF51621 35 258 4.08E-26 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SMALA_RS11905 bade7ee61b4248f01701f245c0d9f49f 395 SUPERFAMILY SSF51621 289 322 4.08E-26 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SMALA_RS11905 bade7ee61b4248f01701f245c0d9f49f 395 Pfam PF15617 C-C_Bond_Lyase of the TIM-Barrel fold 31 378 7.4E-129 T 29-03-2018 SMALA_RS20510 ed1712e3a2a1786364d62b43317b8bf0 139 SUPERFAMILY SSF46785 15 110 4.12E-32 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS20510 ed1712e3a2a1786364d62b43317b8bf0 139 Pfam PF01638 HxlR-like helix-turn-helix 25 111 1.3E-25 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type SMALA_RS20510 ed1712e3a2a1786364d62b43317b8bf0 139 Gene3D G3DSA:1.10.10.10 12 125 7.5E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS30060 e9dd2b7d4a797548e1ba9441423c9bb0 442 Pfam PF01179 Copper amine oxidase, enzyme domain 62 425 1.3E-37 T 29-03-2018 IPR015798 Copper amine oxidase, C-terminal GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 SMALA_RS30060 e9dd2b7d4a797548e1ba9441423c9bb0 442 SUPERFAMILY SSF49998 48 427 4.45E-71 T 29-03-2018 IPR015798 Copper amine oxidase, C-terminal GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 SMALA_RS30060 e9dd2b7d4a797548e1ba9441423c9bb0 442 Gene3D G3DSA:2.70.98.20 42 432 4.5E-70 T 29-03-2018 IPR015798 Copper amine oxidase, C-terminal GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 SMALA_RS15880 b04449687bba35df87a3c3a93a4d8d7f 189 SUPERFAMILY SSF51182 20 149 1.01E-31 T 29-03-2018 IPR011051 RmlC-like cupin domain SMALA_RS15880 b04449687bba35df87a3c3a93a4d8d7f 189 Pfam PF05995 Cysteine dioxygenase type I 20 149 2.6E-22 T 29-03-2018 IPR010300 Cysteine dioxygenase type I GO:0005506|GO:0016702|GO:0055114 KEGG: 00270+1.13.11.20|KEGG: 00430+1.13.11.20|MetaCyc: PWY-5331|Reactome: R-HSA-1614558 SMALA_RS15880 b04449687bba35df87a3c3a93a4d8d7f 189 Gene3D G3DSA:2.60.120.10 9 164 2.3E-35 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SMALA_RS29775 d9b201c44ceb1c3c4681a83debb1cd63 300 SUPERFAMILY SSF161098 28 300 1.64E-70 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS29775 d9b201c44ceb1c3c4681a83debb1cd63 300 Gene3D G3DSA:1.10.3720.10 30 292 4.7E-45 T 29-03-2018 SMALA_RS29775 d9b201c44ceb1c3c4681a83debb1cd63 300 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 110 294 2.4E-21 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS24020 c85c1a7656b7a844b9738db4f9e9f996 120 SUPERFAMILY SSF54593 1 119 1.02E-22 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS24020 c85c1a7656b7a844b9738db4f9e9f996 120 Gene3D G3DSA:3.10.180.10 6 119 1.4E-23 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS32990 fa4af064e2ad41527b40c06c59d2a200 218 SMART SM00756 25 170 1.9E-46 T 29-03-2018 IPR012932 Vitamin K epoxide reductase Reactome: R-HSA-6806664 SMALA_RS32990 fa4af064e2ad41527b40c06c59d2a200 218 Pfam PF07884 Vitamin K epoxide reductase family 31 166 3.0E-26 T 29-03-2018 IPR012932 Vitamin K epoxide reductase Reactome: R-HSA-6806664 SMALA_RS09460 e58e4f2cdfc257993611db6ce99c8cf7 418 Gene3D G3DSA:3.40.640.10 40 292 9.3E-59 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS09460 e58e4f2cdfc257993611db6ce99c8cf7 418 Pfam PF00266 Aminotransferase class-V 31 406 1.4E-151 T 29-03-2018 IPR000192 Aminotransferase class V domain SMALA_RS09460 e58e4f2cdfc257993611db6ce99c8cf7 418 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 12 418 1.9E-185 T 29-03-2018 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 SMALA_RS09460 e58e4f2cdfc257993611db6ce99c8cf7 418 SUPERFAMILY SSF53383 9 413 3.93E-123 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS09460 e58e4f2cdfc257993611db6ce99c8cf7 418 Gene3D G3DSA:3.90.1150.10 293 413 5.2E-43 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS12150 c1c32b35294ec4ea3369c2de2c6ac240 142 SMART SM00347 29 127 1.6E-13 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS12150 c1c32b35294ec4ea3369c2de2c6ac240 142 Gene3D G3DSA:1.10.10.10 3 139 3.0E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS12150 c1c32b35294ec4ea3369c2de2c6ac240 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 69 84 1.4E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS12150 c1c32b35294ec4ea3369c2de2c6ac240 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 52 68 1.4E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS12150 c1c32b35294ec4ea3369c2de2c6ac240 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 88 104 1.4E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS12150 c1c32b35294ec4ea3369c2de2c6ac240 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 117 137 1.4E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS12150 c1c32b35294ec4ea3369c2de2c6ac240 142 Pfam PF12802 MarR family 35 91 3.1E-13 T 29-03-2018 SMALA_RS12150 c1c32b35294ec4ea3369c2de2c6ac240 142 SUPERFAMILY SSF46785 5 139 3.3E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS42170 dadd2bc49995baec8c831051425125e8 213 Gene3D G3DSA:1.10.10.10 8 212 6.6E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS42170 dadd2bc49995baec8c831051425125e8 213 SUPERFAMILY SSF46894 141 210 1.05E-6 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS25745 8e4b3791662b6d2f167a15f1e4b8f2dc 338 Gene3D G3DSA:3.40.630.30 81 337 1.9E-22 T 29-03-2018 SMALA_RS25745 8e4b3791662b6d2f167a15f1e4b8f2dc 338 Pfam PF00583 Acetyltransferase (GNAT) family 263 321 3.0E-12 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SMALA_RS25745 8e4b3791662b6d2f167a15f1e4b8f2dc 338 SUPERFAMILY SSF55729 233 331 8.23E-20 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS31210 1bc619b94fabaf40af4de88ae0ec93f8 103 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 4 94 1.0E-25 T 29-03-2018 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 SMALA_RS31210 1bc619b94fabaf40af4de88ae0ec93f8 103 Gene3D G3DSA:3.30.1360.20 4 103 8.0E-26 T 29-03-2018 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 SMALA_RS31210 1bc619b94fabaf40af4de88ae0ec93f8 103 SUPERFAMILY SSF55248 3 95 2.75E-25 T 29-03-2018 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 SMALA_RS31210 1bc619b94fabaf40af4de88ae0ec93f8 103 Hamap MF_00434 Putative pterin-4-alpha-carbinolamine dehydratase. 3 95 21.143 T 29-03-2018 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 SMALA_RS13570 89fc8545ad8ecf91bf183cba1fa1a7f0 357 Pfam PF07070 SpoOM protein 3 225 9.6E-62 T 29-03-2018 IPR009776 Sporulation stage 0, protein M SMALA_RS17680 5b6b310e86eb5c6566c5c7d3ebf27c98 160 SUPERFAMILY SSF141259 2 65 3.66E-15 T 29-03-2018 IPR003711 CarD-like/TRCF domain SMALA_RS17680 5b6b310e86eb5c6566c5c7d3ebf27c98 160 SMART SM01058 2 112 1.2E-32 T 29-03-2018 IPR003711 CarD-like/TRCF domain SMALA_RS17680 5b6b310e86eb5c6566c5c7d3ebf27c98 160 Pfam PF02559 CarD-like/TRCF domain 3 111 1.9E-18 T 29-03-2018 IPR003711 CarD-like/TRCF domain SMALA_RS04320 a42b6336bd9700e3d67f4caa0fe6e462 363 Gene3D G3DSA:3.40.50.1100 148 314 3.2E-30 T 29-03-2018 SMALA_RS04320 a42b6336bd9700e3d67f4caa0fe6e462 363 SUPERFAMILY SSF53686 14 319 3.93E-60 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMALA_RS04320 a42b6336bd9700e3d67f4caa0fe6e462 363 Gene3D G3DSA:3.40.50.1100 47 147 8.0E-22 T 29-03-2018 SMALA_RS04320 a42b6336bd9700e3d67f4caa0fe6e462 363 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 18 298 1.4E-45 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMALA_RS03320 abdaf0c814868b15cc9fb917feca2df7 109 Gene3D G3DSA:3.90.50.10 3 108 7.7E-23 T 29-03-2018 SMALA_RS03320 abdaf0c814868b15cc9fb917feca2df7 109 Pfam PF05239 PRC-barrel domain 12 72 5.1E-11 T 29-03-2018 IPR027275 PRC-barrel domain SMALA_RS03320 abdaf0c814868b15cc9fb917feca2df7 109 SUPERFAMILY SSF50346 9 107 2.51E-24 T 29-03-2018 IPR011033 PRC-barrel-like SMALA_RS30610 f7120cd0f518f5f631d24158d667191e 303 SMART SM00062 80 303 1.5E-40 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SMALA_RS30610 f7120cd0f518f5f631d24158d667191e 303 Gene3D G3DSA:3.40.190.10 228 303 1.9E-6 T 29-03-2018 SMALA_RS30610 f7120cd0f518f5f631d24158d667191e 303 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 81 302 3.7E-43 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SMALA_RS30610 f7120cd0f518f5f631d24158d667191e 303 SUPERFAMILY SSF53850 25 36 3.93E-52 T 29-03-2018 SMALA_RS30610 f7120cd0f518f5f631d24158d667191e 303 SUPERFAMILY SSF53850 70 302 3.93E-52 T 29-03-2018 SMALA_RS30610 f7120cd0f518f5f631d24158d667191e 303 Gene3D G3DSA:3.40.190.10 69 227 5.3E-33 T 29-03-2018 SMALA_RS19770 d9f83a4598266c3a3b4d676dadda1581 451 Gene3D G3DSA:2.60.120.380 218 348 0.0013 T 29-03-2018 SMALA_RS19770 d9f83a4598266c3a3b4d676dadda1581 451 Gene3D G3DSA:2.60.120.380 46 179 0.0065 T 29-03-2018 SMALA_RS04825 35086ad0551288fdc0341344835593a8 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 3.5E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS04825 35086ad0551288fdc0341344835593a8 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 3.5E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS04825 35086ad0551288fdc0341344835593a8 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 3.5E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS04825 35086ad0551288fdc0341344835593a8 312 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 1.3E-21 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS04825 35086ad0551288fdc0341344835593a8 312 SUPERFAMILY SSF53850 92 299 9.23E-36 T 29-03-2018 SMALA_RS04825 35086ad0551288fdc0341344835593a8 312 Gene3D G3DSA:1.10.10.10 1 82 1.4E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS04825 35086ad0551288fdc0341344835593a8 312 SUPERFAMILY SSF46785 2 86 5.88E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS04825 35086ad0551288fdc0341344835593a8 312 Gene3D G3DSA:3.40.190.10 89 178 1.4E-21 T 29-03-2018 SMALA_RS04825 35086ad0551288fdc0341344835593a8 312 Gene3D G3DSA:3.40.190.10 179 271 9.3E-24 T 29-03-2018 SMALA_RS04825 35086ad0551288fdc0341344835593a8 312 Pfam PF03466 LysR substrate binding domain 89 294 2.8E-42 T 29-03-2018 IPR005119 LysR, substrate-binding SMALA_RS32425 a05205d7c2fc31b179144e2b0d8ca162 739 TIGRFAM TIGR00178 monomer_idh: isocitrate dehydrogenase, NADP-dependent 3 738 0.0 T 29-03-2018 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 SMALA_RS32425 a05205d7c2fc31b179144e2b0d8ca162 739 PIRSF PIRSF009407 1 739 0.0 T 29-03-2018 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 SMALA_RS32425 a05205d7c2fc31b179144e2b0d8ca162 739 Gene3D G3DSA:3.40.718.10 432 709 8.2E-41 T 29-03-2018 SMALA_RS32425 a05205d7c2fc31b179144e2b0d8ca162 739 Pfam PF03971 Monomeric isocitrate dehydrogenase 5 735 0.0 T 29-03-2018 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 SMALA_RS32425 a05205d7c2fc31b179144e2b0d8ca162 739 SUPERFAMILY SSF53659 4 738 0.0 T 29-03-2018 SMALA_RS32425 a05205d7c2fc31b179144e2b0d8ca162 739 Gene3D G3DSA:3.40.718.10 27 362 1.2E-42 T 29-03-2018 SMALA_RS08730 d046d06a5d34510392f8d68ca34d9b5f 549 Gene3D G3DSA:1.10.10.60 473 522 1.4E-7 T 29-03-2018 SMALA_RS08730 d046d06a5d34510392f8d68ca34d9b5f 549 Pfam PF13556 PucR C-terminal helix-turn-helix domain 486 544 2.4E-18 T 29-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain SMALA_RS08730 d046d06a5d34510392f8d68ca34d9b5f 549 Pfam PF07905 Purine catabolism regulatory protein-like family 12 132 3.4E-37 T 29-03-2018 IPR012914 Purine catabolism PurC-like domain SMALA_RS08730 d046d06a5d34510392f8d68ca34d9b5f 549 Gene3D G3DSA:3.40.50.2300 46 159 7.0E-4 T 29-03-2018 SMALA_RS31770 61d6249c7582582165e0ba2f38009628 81 Pfam PF05120 Gas vesicle protein G 7 78 2.0E-26 T 29-03-2018 IPR007804 Gas vesicle protein GvpG SMALA_RS31770 61d6249c7582582165e0ba2f38009628 81 Gene3D G3DSA:1.10.10.10 7 80 1.7E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS01365 54a80e2e39f953a001ed3fad856941a4 418 Gene3D G3DSA:1.20.1250.20 212 400 1.5E-14 T 29-03-2018 SMALA_RS01365 54a80e2e39f953a001ed3fad856941a4 418 Gene3D G3DSA:1.20.1250.20 11 205 3.3E-21 T 29-03-2018 SMALA_RS01365 54a80e2e39f953a001ed3fad856941a4 418 SUPERFAMILY SSF103473 15 406 6.41E-45 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS01365 54a80e2e39f953a001ed3fad856941a4 418 Pfam PF05977 Transmembrane secretion effector 15 400 1.8E-30 T 29-03-2018 IPR010290 Transmembrane secretion effector SMALA_RS21160 d69e234749cc5f561a42936cd005ca2a 999 Gene3D G3DSA:3.40.50.300 165 438 3.0E-4 T 29-03-2018 SMALA_RS21160 d69e234749cc5f561a42936cd005ca2a 999 Pfam PF10593 Z1 domain 489 741 9.8E-58 T 29-03-2018 IPR018310 Putative endonuclease, Z1 domain SMALA_RS13525 9f54c92fe780c541802a2edf3c485905 169 Pfam PF00436 Single-strand binding protein family 6 94 1.3E-14 T 29-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 SMALA_RS13525 9f54c92fe780c541802a2edf3c485905 169 Gene3D G3DSA:2.40.50.140 1 153 1.6E-39 T 29-03-2018 SMALA_RS13525 9f54c92fe780c541802a2edf3c485905 169 SUPERFAMILY SSF50249 5 118 1.58E-16 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMALA_RS25775 5172500eab019339e063e3f6a55c06f9 356 Gene3D G3DSA:3.30.70.360 175 276 1.6E-23 T 29-03-2018 SMALA_RS25775 5172500eab019339e063e3f6a55c06f9 356 Pfam PF01546 Peptidase family M20/M25/M40 69 350 1.0E-20 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 SMALA_RS25775 5172500eab019339e063e3f6a55c06f9 356 TIGRFAM TIGR01900 dapE-gram_pos: succinyl-diaminopimelate desuccinylase 11 355 1.6E-159 T 29-03-2018 IPR010174 Succinyl-diaminopimelate desuccinylase, DapE GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 SMALA_RS25775 5172500eab019339e063e3f6a55c06f9 356 SUPERFAMILY SSF55031 170 272 4.19E-21 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain SMALA_RS25775 5172500eab019339e063e3f6a55c06f9 356 Pfam PF07687 Peptidase dimerisation domain 170 266 3.2E-15 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain SMALA_RS25775 5172500eab019339e063e3f6a55c06f9 356 Gene3D G3DSA:3.40.630.10 7 174 2.5E-26 T 29-03-2018 SMALA_RS25775 5172500eab019339e063e3f6a55c06f9 356 SUPERFAMILY SSF53187 276 356 3.28E-42 T 29-03-2018 SMALA_RS25775 5172500eab019339e063e3f6a55c06f9 356 SUPERFAMILY SSF53187 14 182 3.28E-42 T 29-03-2018 SMALA_RS17805 34303cdeafa3ae362105f127bdce4e44 579 Pfam PF12708 Pectate lyase superfamily protein 100 185 8.7E-19 T 29-03-2018 IPR024535 Pectate lyase superfamily protein SMALA_RS17805 34303cdeafa3ae362105f127bdce4e44 579 SUPERFAMILY SSF51126 356 493 1.65E-27 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor SMALA_RS17805 34303cdeafa3ae362105f127bdce4e44 579 SUPERFAMILY SSF51126 93 205 1.65E-27 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor SMALA_RS17805 34303cdeafa3ae362105f127bdce4e44 579 Gene3D G3DSA:2.160.20.10 89 543 1.1E-34 T 29-03-2018 IPR012334 Pectin lyase fold SMALA_RS09035 d7b0f757b200b389ac2a16840c348441 118 Pfam PF04341 Protein of unknown function, DUF485 25 111 6.1E-31 T 29-03-2018 IPR007436 Protein of unknown function DUF485 SMALA_RS00600 d59125a687b1648fc793dda34172c8ee 638 Pfam PF13515 Fusaric acid resistance protein-like 356 475 1.6E-13 T 29-03-2018 SMALA_RS00600 d59125a687b1648fc793dda34172c8ee 638 Gene3D G3DSA:3.90.1150.10 185 523 0.0027 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS31995 27ea565396900294df0dcb9166a9e9db 576 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 23 513 6.4E-173 T 29-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 SMALA_RS31995 27ea565396900294df0dcb9166a9e9db 576 ProSitePatterns PS01303 BCCT family of transporters signature. 330 339 - T 29-03-2018 IPR018093 BCCT transporter, conserved site GO:0005215|GO:0006810|GO:0016020 SMALA_RS31995 27ea565396900294df0dcb9166a9e9db 576 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 61 513 3.9E-158 T 29-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 SMALA_RS27550 c2a37a22e54c930f0b5d765f7745003b 586 Gene3D G3DSA:3.40.190.10 204 341 3.4E-25 T 29-03-2018 SMALA_RS27550 c2a37a22e54c930f0b5d765f7745003b 586 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 103 493 1.5E-73 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain SMALA_RS27550 c2a37a22e54c930f0b5d765f7745003b 586 Gene3D G3DSA:3.90.76.10 76 203 1.4E-25 T 29-03-2018 SMALA_RS27550 c2a37a22e54c930f0b5d765f7745003b 586 PIRSF PIRSF002741 7 581 2.4E-60 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 SMALA_RS27550 c2a37a22e54c930f0b5d765f7745003b 586 SUPERFAMILY SSF53850 54 579 2.17E-94 T 29-03-2018 SMALA_RS27550 c2a37a22e54c930f0b5d765f7745003b 586 Gene3D G3DSA:3.10.105.10 342 555 1.3E-34 T 29-03-2018 SMALA_RS05205 646f8c5d0271c939b029e57acf02e9c9 356 SUPERFAMILY SSF53822 53 333 1.73E-40 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SMALA_RS05205 646f8c5d0271c939b029e57acf02e9c9 356 Pfam PF13407 Periplasmic binding protein domain 54 304 6.3E-36 T 29-03-2018 IPR025997 Periplasmic binding protein SMALA_RS05205 646f8c5d0271c939b029e57acf02e9c9 356 Gene3D G3DSA:3.40.50.2300 171 309 1.4E-22 T 29-03-2018 SMALA_RS05205 646f8c5d0271c939b029e57acf02e9c9 356 Gene3D G3DSA:3.40.50.2300 48 170 3.1E-12 T 29-03-2018 SMALA_RS36625 08a8e675ad7bdb9998f16059c5050336 108 Pfam PF04237 YjbR 12 99 4.5E-19 T 29-03-2018 IPR007351 Uncharacterised protein YjbR SMALA_RS36625 08a8e675ad7bdb9998f16059c5050336 108 Gene3D G3DSA:3.30.1460.30 2 103 5.9E-18 T 29-03-2018 SMALA_RS36625 08a8e675ad7bdb9998f16059c5050336 108 SUPERFAMILY SSF142906 1 104 5.62E-22 T 29-03-2018 SMALA_RS39890 f7f848b90627b8baea22b6fa0046e367 213 Pfam PF01323 DSBA-like thioredoxin domain 7 169 7.3E-8 T 29-03-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 SMALA_RS39890 f7f848b90627b8baea22b6fa0046e367 213 SUPERFAMILY SSF52833 7 170 3.2E-20 T 29-03-2018 IPR012336 Thioredoxin-like fold SMALA_RS39890 f7f848b90627b8baea22b6fa0046e367 213 Gene3D G3DSA:3.40.30.10 6 61 4.7E-11 T 29-03-2018 SMALA_RS39890 f7f848b90627b8baea22b6fa0046e367 213 Gene3D G3DSA:3.40.30.10 62 171 2.8E-10 T 29-03-2018 SMALA_RS10500 ec738d206ccd3a7d64ae1d1eea7bd2ed 244 SUPERFAMILY SSF144091 18 224 6.15E-38 T 29-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 SMALA_RS10500 ec738d206ccd3a7d64ae1d1eea7bd2ed 244 Gene3D G3DSA:1.20.1540.10 17 224 1.0E-42 T 29-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 SMALA_RS10500 ec738d206ccd3a7d64ae1d1eea7bd2ed 244 Pfam PF01694 Rhomboid family 75 227 4.2E-38 T 29-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 SMALA_RS39380 6a4ff1c7be9900a7175e2c817327758c 332 Pfam PF07883 Cupin domain 75 142 2.4E-11 T 29-03-2018 IPR013096 Cupin 2, conserved barrel SMALA_RS39380 6a4ff1c7be9900a7175e2c817327758c 332 Gene3D G3DSA:2.60.120.10 170 311 4.5E-11 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SMALA_RS39380 6a4ff1c7be9900a7175e2c817327758c 332 Gene3D G3DSA:2.60.120.10 22 150 4.2E-15 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SMALA_RS39380 6a4ff1c7be9900a7175e2c817327758c 332 SUPERFAMILY SSF51182 54 318 5.6E-33 T 29-03-2018 IPR011051 RmlC-like cupin domain SMALA_RS10825 1669757dae9581c31fe1c07e515df6bd 424 Pfam PF13796 Putative sensor 14 198 3.8E-13 T 29-03-2018 IPR025828 Putative sensor domain SMALA_RS10825 1669757dae9581c31fe1c07e515df6bd 424 SUPERFAMILY SSF55874 306 415 3.41E-13 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS10825 1669757dae9581c31fe1c07e515df6bd 424 Gene3D G3DSA:3.30.565.10 289 422 4.4E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS10825 1669757dae9581c31fe1c07e515df6bd 424 Pfam PF07730 Histidine kinase 227 294 3.4E-15 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMALA_RS32025 ca970f6ceb403f4ff94401f5f99ad092 204 Gene3D G3DSA:3.90.79.10 20 198 1.7E-31 T 29-03-2018 SMALA_RS32025 ca970f6ceb403f4ff94401f5f99ad092 204 PIRSF PIRSF018427 9 201 4.0E-51 T 29-03-2018 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: R-HSA-191273 SMALA_RS32025 ca970f6ceb403f4ff94401f5f99ad092 204 Hamap MF_00202 Isopentenyl-diphosphate Delta-isomerase [idi]. 26 198 31.046 T 29-03-2018 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: R-HSA-191273 SMALA_RS32025 ca970f6ceb403f4ff94401f5f99ad092 204 TIGRFAM TIGR02150 IPP_isom_1: isopentenyl-diphosphate delta-isomerase 30 185 1.1E-36 T 29-03-2018 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: R-HSA-191273 SMALA_RS32025 ca970f6ceb403f4ff94401f5f99ad092 204 Pfam PF00293 NUDIX domain 52 183 1.4E-25 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SMALA_RS32025 ca970f6ceb403f4ff94401f5f99ad092 204 SUPERFAMILY SSF55811 28 189 2.3E-44 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMALA_RS13810 9d8a3d2a6e91aaa19a66ca541afdf729 169 Pfam PF03703 Bacterial PH domain 79 156 1.4E-14 T 29-03-2018 IPR005182 Domain of unknown function DUF304 SMALA_RS00880 034e5dced50d6215bce16db6235ae740 215 SUPERFAMILY SSF53335 14 191 4.71E-35 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS00880 034e5dced50d6215bce16db6235ae740 215 Pfam PF13649 Methyltransferase domain 50 143 1.7E-15 T 29-03-2018 SMALA_RS00880 034e5dced50d6215bce16db6235ae740 215 Gene3D G3DSA:3.40.50.150 3 202 2.6E-30 T 29-03-2018 SMALA_RS17855 b2c44b1ddc1143672dadbc7f51ea6d93 311 SUPERFAMILY SSF53850 1 22 7.12E-41 T 29-03-2018 SMALA_RS17855 b2c44b1ddc1143672dadbc7f51ea6d93 311 SUPERFAMILY SSF53850 54 295 7.12E-41 T 29-03-2018 SMALA_RS17855 b2c44b1ddc1143672dadbc7f51ea6d93 311 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 70 294 8.8E-37 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SMALA_RS17855 b2c44b1ddc1143672dadbc7f51ea6d93 311 Gene3D G3DSA:3.40.190.10 165 254 2.9E-20 T 29-03-2018 SMALA_RS17855 b2c44b1ddc1143672dadbc7f51ea6d93 311 SMART SM00062 64 297 2.8E-22 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SMALA_RS17855 b2c44b1ddc1143672dadbc7f51ea6d93 311 Gene3D G3DSA:3.40.190.10 57 164 2.3E-10 T 29-03-2018 SMALA_RS23855 49c83afe70e351bbdcd52bf025bbe9f9 406 Gene3D G3DSA:1.20.1440.110 8 123 7.4E-33 T 29-03-2018 SMALA_RS23855 49c83afe70e351bbdcd52bf025bbe9f9 406 SUPERFAMILY SSF53474 10 263 2.7E-63 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS23855 49c83afe70e351bbdcd52bf025bbe9f9 406 SUPERFAMILY SSF53474 295 399 2.7E-63 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS23855 49c83afe70e351bbdcd52bf025bbe9f9 406 Pfam PF00561 alpha/beta hydrolase fold 167 291 2.1E-8 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS23855 49c83afe70e351bbdcd52bf025bbe9f9 406 Gene3D G3DSA:3.40.50.1820 124 401 2.8E-36 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS11080 22fd2b93473676f3645391231a4b45fd 419 Gene3D G3DSA:1.25.40.10 144 406 3.3E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS11080 22fd2b93473676f3645391231a4b45fd 419 Gene3D G3DSA:1.10.260.40 4 95 1.4E-9 T 29-03-2018 SMALA_RS11080 22fd2b93473676f3645391231a4b45fd 419 SUPERFAMILY SSF48452 176 370 1.74E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS11080 22fd2b93473676f3645391231a4b45fd 419 SMART SM00530 6 73 0.0019 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS25150 e3a8f6631cef26c42da89572f075632a 587 Gene3D G3DSA:3.40.50.1820 40 391 1.3E-37 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS25150 e3a8f6631cef26c42da89572f075632a 587 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 75 341 5.3E-50 T 29-03-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 SMALA_RS25150 e3a8f6631cef26c42da89572f075632a 587 Gene3D G3DSA:2.60.120.260 392 544 1.1E-18 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS25150 e3a8f6631cef26c42da89572f075632a 587 SUPERFAMILY SSF49785 390 543 5.1E-14 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS25150 e3a8f6631cef26c42da89572f075632a 587 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 431 531 1.3E-21 T 29-03-2018 IPR005674 CocE/Serine esterase GO:0016787 SMALA_RS25150 e3a8f6631cef26c42da89572f075632a 587 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 79 429 1.6E-85 T 29-03-2018 IPR005674 CocE/Serine esterase GO:0016787 SMALA_RS25150 e3a8f6631cef26c42da89572f075632a 587 SMART SM00939 364 549 6.2E-17 T 29-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 SMALA_RS25150 e3a8f6631cef26c42da89572f075632a 587 SUPERFAMILY SSF53474 61 398 9.08E-46 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS25150 e3a8f6631cef26c42da89572f075632a 587 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 380 480 3.2E-6 T 29-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 SMALA_RS32540 4873cad53e94245b760b24b820e2df5f 167 SUPERFAMILY SSF55729 1 144 4.12E-25 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS32540 4873cad53e94245b760b24b820e2df5f 167 Gene3D G3DSA:3.40.630.30 2 146 1.8E-27 T 29-03-2018 SMALA_RS32540 4873cad53e94245b760b24b820e2df5f 167 Pfam PF00583 Acetyltransferase (GNAT) family 41 137 2.5E-12 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SMALA_RS28250 b8ac9a18724d691b9cc56f839fc9bb25 368 PIRSF PIRSF006004 14 368 6.1E-124 T 29-03-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SMALA_RS28250 b8ac9a18724d691b9cc56f839fc9bb25 368 SUPERFAMILY SSF102114 113 339 4.97E-17 T 29-03-2018 SMALA_RS28250 b8ac9a18724d691b9cc56f839fc9bb25 368 Gene3D G3DSA:3.20.20.70 28 343 1.4E-37 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS28250 b8ac9a18724d691b9cc56f839fc9bb25 368 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 20 367 4.4E-96 T 29-03-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SMALA_RS28250 b8ac9a18724d691b9cc56f839fc9bb25 368 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 19 368 68.04 T 29-03-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SMALA_RS28250 b8ac9a18724d691b9cc56f839fc9bb25 368 Pfam PF04055 Radical SAM superfamily 124 297 1.7E-16 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 SMALA_RS27350 91bd76d03a3fd166ad4640d9cf1ee2fb 249 Gene3D G3DSA:3.40.50.150 2 235 4.2E-33 T 29-03-2018 SMALA_RS27350 91bd76d03a3fd166ad4640d9cf1ee2fb 249 Pfam PF08241 Methyltransferase domain 50 138 6.0E-20 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 SMALA_RS27350 91bd76d03a3fd166ad4640d9cf1ee2fb 249 SUPERFAMILY SSF53335 17 205 9.91E-32 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS41655 bf8754289018a9766165e96110b5b806 356 SUPERFAMILY SSF75005 24 292 3.93E-38 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain SMALA_RS41655 bf8754289018a9766165e96110b5b806 356 Gene3D G3DSA:2.115.10.20 28 341 1.1E-34 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain SMALA_RS41655 bf8754289018a9766165e96110b5b806 356 Pfam PF04616 Glycosyl hydrolases family 43 39 273 6.5E-27 T 29-03-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 SMALA_RS05125 afc328d44b57aad84488fc2c66d7acb4 219 Pfam PF00072 Response regulator receiver domain 7 119 5.7E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS05125 afc328d44b57aad84488fc2c66d7acb4 219 SUPERFAMILY SSF52172 4 138 4.98E-31 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS05125 afc328d44b57aad84488fc2c66d7acb4 219 SMART SM00421 155 212 6.3E-27 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS05125 afc328d44b57aad84488fc2c66d7acb4 219 ProSitePatterns PS00622 LuxR-type HTH domain signature. 172 199 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS05125 afc328d44b57aad84488fc2c66d7acb4 219 SMART SM00448 5 120 7.0E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS05125 afc328d44b57aad84488fc2c66d7acb4 219 Gene3D G3DSA:3.40.50.2300 4 138 8.5E-35 T 29-03-2018 SMALA_RS05125 afc328d44b57aad84488fc2c66d7acb4 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 188 1.6E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS05125 afc328d44b57aad84488fc2c66d7acb4 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 188 200 1.6E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS05125 afc328d44b57aad84488fc2c66d7acb4 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 172 1.6E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS05125 afc328d44b57aad84488fc2c66d7acb4 219 Gene3D G3DSA:1.10.10.10 139 217 2.4E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS05125 afc328d44b57aad84488fc2c66d7acb4 219 SUPERFAMILY SSF46894 152 218 6.12E-23 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS05125 afc328d44b57aad84488fc2c66d7acb4 219 Pfam PF00196 Bacterial regulatory proteins, luxR family 157 212 1.3E-19 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS09055 c3761d04d3b7345bcb6625849da282a4 292 Pfam PF04116 Fatty acid hydroxylase superfamily 86 218 2.5E-27 T 29-03-2018 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0008610|GO:0016491|GO:0055114 SMALA_RS25780 a45f782e8c4d8a0d987b9b2a600e1a44 249 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 71 244 3.1E-43 T 29-03-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG SMALA_RS25780 a45f782e8c4d8a0d987b9b2a600e1a44 249 Pfam PF03641 Possible lysine decarboxylase 113 241 1.3E-33 T 29-03-2018 IPR031100 LOG family SMALA_RS25780 a45f782e8c4d8a0d987b9b2a600e1a44 249 SUPERFAMILY SSF102405 42 243 2.59E-64 T 29-03-2018 SMALA_RS25780 a45f782e8c4d8a0d987b9b2a600e1a44 249 Gene3D G3DSA:3.40.50.450 48 247 7.3E-68 T 29-03-2018 SMALA_RS36535 6045671a6a05387d1c825fe253f6eee7 269 Gene3D G3DSA:3.75.10.10 7 268 6.7E-67 T 29-03-2018 SMALA_RS36535 6045671a6a05387d1c825fe253f6eee7 269 Pfam PF02274 Amidinotransferase 65 268 1.5E-19 T 29-03-2018 SMALA_RS36535 6045671a6a05387d1c825fe253f6eee7 269 SUPERFAMILY SSF55909 6 269 6.6E-59 T 29-03-2018 SMALA_RS30885 95a60b23eaf20be86914dc6690ca3404 672 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 9 498 2.6E-139 T 29-03-2018 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMALA_RS30885 95a60b23eaf20be86914dc6690ca3404 672 Gene3D G3DSA:3.40.50.280 515 665 4.2E-37 T 29-03-2018 SMALA_RS30885 95a60b23eaf20be86914dc6690ca3404 672 Pfam PF02310 B12 binding domain 536 642 3.9E-18 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 SMALA_RS30885 95a60b23eaf20be86914dc6690ca3404 672 SUPERFAMILY SSF51703 6 494 7.85E-161 T 29-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMALA_RS30885 95a60b23eaf20be86914dc6690ca3404 672 SUPERFAMILY SSF52242 514 655 5.1E-45 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 SMALA_RS30885 95a60b23eaf20be86914dc6690ca3404 672 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 533 661 7.8E-40 T 29-03-2018 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMALA_RS30885 95a60b23eaf20be86914dc6690ca3404 672 Gene3D G3DSA:3.20.20.240 2 494 4.1E-168 T 29-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMALA_RS30885 95a60b23eaf20be86914dc6690ca3404 672 Pfam PF01642 Methylmalonyl-CoA mutase 8 492 1.6E-131 T 29-03-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMALA_RS20360 9852ec366d4b4d2857163f9e9629bd1c 399 SMART SM00530 11 64 6.9E-10 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS20360 9852ec366d4b4d2857163f9e9629bd1c 399 Pfam PF13560 Helix-turn-helix domain 8 62 1.3E-11 T 29-03-2018 SMALA_RS20360 9852ec366d4b4d2857163f9e9629bd1c 399 SUPERFAMILY SSF48452 159 230 3.47E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS20360 9852ec366d4b4d2857163f9e9629bd1c 399 Gene3D G3DSA:1.25.40.10 139 397 6.9E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS20360 9852ec366d4b4d2857163f9e9629bd1c 399 Gene3D G3DSA:1.10.260.40 3 66 7.4E-15 T 29-03-2018 SMALA_RS20360 9852ec366d4b4d2857163f9e9629bd1c 399 SUPERFAMILY SSF47413 6 69 2.0E-12 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS37700 863ff434231f432c300619e5841ad61f 241 SUPERFAMILY SSF49464 144 193 1.77E-5 T 29-03-2018 IPR008969 Carboxypeptidase-like, regulatory domain SMALA_RS37700 863ff434231f432c300619e5841ad61f 241 Gene3D G3DSA:2.60.40.1120 144 235 7.8E-5 T 29-03-2018 SMALA_RS22960 33d47eeff9721e4da3087fe3d5ede430 375 SMART SM01240 14 370 2.5E-28 T 29-03-2018 SMALA_RS22960 33d47eeff9721e4da3087fe3d5ede430 375 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 15 297 7.3E-43 T 29-03-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 SMALA_RS22960 33d47eeff9721e4da3087fe3d5ede430 375 TIGRFAM TIGR01304 IMP_DH_rel_2: IMP dehydrogenase family protein 4 367 1.0E-194 T 29-03-2018 IPR005992 IMP dehydrogenase-related 2 GO:0016491|GO:0055114 SMALA_RS22960 33d47eeff9721e4da3087fe3d5ede430 375 SUPERFAMILY SSF51412 12 77 5.8E-69 T 29-03-2018 SMALA_RS22960 33d47eeff9721e4da3087fe3d5ede430 375 SUPERFAMILY SSF51412 113 370 5.8E-69 T 29-03-2018 SMALA_RS22960 33d47eeff9721e4da3087fe3d5ede430 375 Gene3D G3DSA:3.20.20.70 15 368 8.4E-48 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS30750 57e61e4038799f29b2458a80110d7d33 653 Gene3D G3DSA:1.25.10.10 24 649 3.1E-6 T 29-03-2018 IPR011989 Armadillo-like helical SMALA_RS17465 94af2253730762fccaa14f5e92f8ef8a 110 Pfam PF11239 Protein of unknown function (DUF3040) 8 76 8.4E-10 T 29-03-2018 IPR021401 Protein of unknown function DUF3040 SMALA_RS33515 26c42b30deb39d04432a61b3410acb1f 522 Gene3D G3DSA:3.30.565.10 247 376 1.5E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS33515 26c42b30deb39d04432a61b3410acb1f 522 SUPERFAMILY SSF55874 249 373 9.2E-11 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS33515 26c42b30deb39d04432a61b3410acb1f 522 Pfam PF07730 Histidine kinase 174 238 1.1E-12 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMALA_RS20260 9e814ae41174daa9fe58afbe3020f9ac 393 Gene3D G3DSA:3.30.565.10 259 392 4.7E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS20260 9e814ae41174daa9fe58afbe3020f9ac 393 Pfam PF07730 Histidine kinase 186 250 2.1E-15 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMALA_RS20260 9e814ae41174daa9fe58afbe3020f9ac 393 SUPERFAMILY SSF55874 273 383 1.22E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS16620 d756934db0b7e22042e2058f45e80454 349 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 103 255 9.1E-47 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain SMALA_RS16620 d756934db0b7e22042e2058f45e80454 349 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 103 256 1.0E-40 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain SMALA_RS28985 51ce38fe7345b06d417609f81ab482b4 548 SMART SM00382 369 532 7.2E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS28985 51ce38fe7345b06d417609f81ab482b4 548 SMART SM00382 29 233 4.5E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS28985 51ce38fe7345b06d417609f81ab482b4 548 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS28985 51ce38fe7345b06d417609f81ab482b4 548 SUPERFAMILY SSF52540 365 542 5.74E-35 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS28985 51ce38fe7345b06d417609f81ab482b4 548 Pfam PF00005 ABC transporter 365 488 2.0E-21 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS28985 51ce38fe7345b06d417609f81ab482b4 548 Pfam PF00005 ABC transporter 20 188 2.6E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS28985 51ce38fe7345b06d417609f81ab482b4 548 Gene3D G3DSA:3.40.50.300 2 326 1.2E-48 T 29-03-2018 SMALA_RS28985 51ce38fe7345b06d417609f81ab482b4 548 ProSitePatterns PS00211 ABC transporters family signature. 460 474 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS28985 51ce38fe7345b06d417609f81ab482b4 548 SUPERFAMILY SSF52540 5 231 3.52E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS28985 51ce38fe7345b06d417609f81ab482b4 548 Gene3D G3DSA:3.40.50.300 361 537 1.4E-33 T 29-03-2018 SMALA_RS23845 b8e8395b2137846a3a237021b9f42e64 752 Gene3D G3DSA:1.20.1640.10 116 334 1.8E-33 T 29-03-2018 SMALA_RS23845 b8e8395b2137846a3a237021b9f42e64 752 Gene3D G3DSA:1.20.1640.10 463 704 6.0E-30 T 29-03-2018 SMALA_RS23845 b8e8395b2137846a3a237021b9f42e64 752 SUPERFAMILY SSF82866 490 703 4.19E-26 T 29-03-2018 SMALA_RS23845 b8e8395b2137846a3a237021b9f42e64 752 Pfam PF03176 MMPL family 416 708 5.8E-35 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 SMALA_RS23845 b8e8395b2137846a3a237021b9f42e64 752 Pfam PF03176 MMPL family 45 378 3.7E-81 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 SMALA_RS23845 b8e8395b2137846a3a237021b9f42e64 752 SUPERFAMILY SSF82866 123 334 1.7E-31 T 29-03-2018 SMALA_RS25290 a7a1f959e380c8c39c8709b8146fed72 389 SUPERFAMILY SSF56801 47 342 4.97E-24 T 29-03-2018 SMALA_RS25290 a7a1f959e380c8c39c8709b8146fed72 389 Gene3D G3DSA:3.40.50.980 41 224 2.4E-14 T 29-03-2018 SMALA_RS25290 a7a1f959e380c8c39c8709b8146fed72 389 Pfam PF00501 AMP-binding enzyme 50 213 4.1E-8 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS23630 315456c43c0bfd39ddf1bfe2b17806e9 244 SUPERFAMILY SSF46689 7 80 1.36E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS23630 315456c43c0bfd39ddf1bfe2b17806e9 244 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 57 1.6E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS23630 315456c43c0bfd39ddf1bfe2b17806e9 244 Gene3D G3DSA:1.10.357.10 5 237 7.9E-27 T 29-03-2018 SMALA_RS17860 711322f6c8bae72447963731d24d85b2 339 Gene3D G3DSA:1.10.3720.10 38 300 6.1E-44 T 29-03-2018 SMALA_RS17860 711322f6c8bae72447963731d24d85b2 339 SUPERFAMILY SSF161098 76 280 3.79E-44 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS17860 711322f6c8bae72447963731d24d85b2 339 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 95 292 3.1E-21 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS17860 711322f6c8bae72447963731d24d85b2 339 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 76 139 9.2E-15 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 SMALA_RS26690 4cbb9c9b99caf72707efe7c0fc50ada9 112 Pfam PF04248 Domain of unknown function (DUF427) 8 103 3.2E-33 T 29-03-2018 IPR007361 Domain of unknown function DUF427 SMALA_RS18160 a6a09b3b5a7b5bf5a0e50c229498f208 235 PIRSF PIRSF006324 2 234 4.2E-50 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 SMALA_RS18160 a6a09b3b5a7b5bf5a0e50c229498f208 235 Pfam PF01810 LysE type translocator 17 232 2.5E-43 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 SMALA_RS29070 5ef65524656fe4a586a8d42b79b8f23d 535 Pfam PF00474 Sodium:solute symporter family 38 454 1.3E-76 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 SMALA_RS13560 fd7cd60acd06ec7bc325a02c46778cab 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 3.1E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS13560 fd7cd60acd06ec7bc325a02c46778cab 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 3.1E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS13560 fd7cd60acd06ec7bc325a02c46778cab 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 3.1E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS13560 fd7cd60acd06ec7bc325a02c46778cab 262 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMALA_RS13560 fd7cd60acd06ec7bc325a02c46778cab 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 1.3E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS13560 fd7cd60acd06ec7bc325a02c46778cab 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 1.3E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS13560 fd7cd60acd06ec7bc325a02c46778cab 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 1.3E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS13560 fd7cd60acd06ec7bc325a02c46778cab 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 1.3E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS13560 fd7cd60acd06ec7bc325a02c46778cab 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 1.3E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS13560 fd7cd60acd06ec7bc325a02c46778cab 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 1.3E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS13560 fd7cd60acd06ec7bc325a02c46778cab 262 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 23 258 1.5E-45 T 29-03-2018 SMALA_RS13560 fd7cd60acd06ec7bc325a02c46778cab 262 SUPERFAMILY SSF51735 14 259 3.1E-69 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS13560 fd7cd60acd06ec7bc325a02c46778cab 262 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 15 197 1.1E-4 T 29-03-2018 SMALA_RS13560 fd7cd60acd06ec7bc325a02c46778cab 262 Gene3D G3DSA:3.40.50.720 54 262 4.0E-57 T 29-03-2018 SMALA_RS13560 fd7cd60acd06ec7bc325a02c46778cab 262 Gene3D G3DSA:3.40.50.720 8 53 9.5E-9 T 29-03-2018 SMALA_RS36065 52855ea3a3bc7371fd3461cd47bf22dd 362 Pfam PF01370 NAD dependent epimerase/dehydratase family 9 245 1.5E-20 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 SMALA_RS36065 52855ea3a3bc7371fd3461cd47bf22dd 362 SUPERFAMILY SSF51735 1 327 1.46E-46 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS36065 52855ea3a3bc7371fd3461cd47bf22dd 362 Gene3D G3DSA:3.40.50.720 3 333 6.3E-41 T 29-03-2018 SMALA_RS29735 4dea91e28abfdfcd7909e8d1c7db6907 293 SUPERFAMILY SSF55729 9 140 5.14E-19 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS29735 4dea91e28abfdfcd7909e8d1c7db6907 293 Pfam PF00583 Acetyltransferase (GNAT) family 35 135 3.0E-8 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SMALA_RS29735 4dea91e28abfdfcd7909e8d1c7db6907 293 Gene3D G3DSA:3.40.630.30 3 176 7.1E-21 T 29-03-2018 SMALA_RS17915 511cd34d12bb7170e32d1078b5e0aba5 130 SUPERFAMILY SSF46785 16 126 4.92E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS17915 511cd34d12bb7170e32d1078b5e0aba5 130 Pfam PF01638 HxlR-like helix-turn-helix 29 114 1.8E-22 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type SMALA_RS17915 511cd34d12bb7170e32d1078b5e0aba5 130 Gene3D G3DSA:1.10.10.10 26 126 2.2E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS28185 494c05c81ddc83ee07697522f7e85906 102 Pfam PF10611 Protein of unknown function (DUF2469) 1 100 1.6E-52 T 29-03-2018 IPR019592 Protein of unknown function DUF2469 SMALA_RS24950 f80fc297c97c144d59850e6e3aead92b 196 SUPERFAMILY SSF55469 14 194 7.72E-44 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMALA_RS24950 f80fc297c97c144d59850e6e3aead92b 196 Gene3D G3DSA:3.40.109.10 9 196 1.8E-36 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMALA_RS24950 f80fc297c97c144d59850e6e3aead92b 196 Pfam PF00881 Nitroreductase family 15 174 1.6E-18 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 SMALA_RS26180 d6048622ad9ef735d6141c56996a48b5 222 SUPERFAMILY SSF53474 10 219 8.4E-20 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS26180 d6048622ad9ef735d6141c56996a48b5 222 Gene3D G3DSA:3.40.50.1820 2 222 8.4E-16 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS07070 43aea5f1c340e2d3b0400d01560c7aff 1284 Gene3D G3DSA:1.20.120.20 12 181 0.0099 T 29-03-2018 SMALA_RS07070 43aea5f1c340e2d3b0400d01560c7aff 1284 Gene3D G3DSA:1.20.120.20 194 441 9.0E-5 T 29-03-2018 SMALA_RS07070 43aea5f1c340e2d3b0400d01560c7aff 1284 Gene3D G3DSA:1.20.5.1230 442 627 5.9E-4 T 29-03-2018 SMALA_RS24490 72e80d744eeacbf589c1eacd867af4aa 538 Pfam PF07969 Amidohydrolase family 46 520 1.4E-63 T 29-03-2018 IPR013108 Amidohydrolase 3 SMALA_RS24490 72e80d744eeacbf589c1eacd867af4aa 538 SUPERFAMILY SSF51556 346 476 1.79E-72 T 29-03-2018 IPR032466 Metal-dependent hydrolase SMALA_RS24490 72e80d744eeacbf589c1eacd867af4aa 538 SUPERFAMILY SSF51556 58 303 1.79E-72 T 29-03-2018 IPR032466 Metal-dependent hydrolase SMALA_RS24490 72e80d744eeacbf589c1eacd867af4aa 538 Gene3D G3DSA:2.30.40.10 1 66 2.4E-18 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS24490 72e80d744eeacbf589c1eacd867af4aa 538 Gene3D G3DSA:2.30.40.10 457 525 3.5E-11 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS24490 72e80d744eeacbf589c1eacd867af4aa 538 Gene3D G3DSA:3.20.20.140 67 456 1.7E-85 T 29-03-2018 SMALA_RS24490 72e80d744eeacbf589c1eacd867af4aa 538 SUPERFAMILY SSF51338 1 58 8.88E-23 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS24490 72e80d744eeacbf589c1eacd867af4aa 538 SUPERFAMILY SSF51338 476 527 8.88E-23 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS11250 024977b66796a0a39a71e01cf0590bb7 87 Pfam PF02148 Zn-finger in ubiquitin-hydrolases and other protein 23 84 1.3E-11 T 29-03-2018 IPR001607 Zinc finger, UBP-type GO:0008270 SMALA_RS11250 024977b66796a0a39a71e01cf0590bb7 87 Gene3D G3DSA:3.30.40.10 5 87 1.0E-17 T 29-03-2018 IPR013083 Zinc finger, RING/FYVE/PHD-type SMALA_RS11250 024977b66796a0a39a71e01cf0590bb7 87 SUPERFAMILY SSF57850 7 86 4.71E-24 T 29-03-2018 SMALA_RS28585 54e16d819dd51982dd026248cd0a4817 411 PRINTS PR00723 Subtilisin serine protease family (S8) signature 98 111 3.2E-12 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related SMALA_RS28585 54e16d819dd51982dd026248cd0a4817 411 PRINTS PR00723 Subtilisin serine protease family (S8) signature 261 277 3.2E-12 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related SMALA_RS28585 54e16d819dd51982dd026248cd0a4817 411 PRINTS PR00723 Subtilisin serine protease family (S8) signature 59 78 3.2E-12 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related SMALA_RS28585 54e16d819dd51982dd026248cd0a4817 411 Gene3D G3DSA:3.40.50.200 31 322 7.7E-71 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMALA_RS28585 54e16d819dd51982dd026248cd0a4817 411 SUPERFAMILY SSF52743 41 318 4.06E-67 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMALA_RS28585 54e16d819dd51982dd026248cd0a4817 411 Pfam PF00082 Subtilase family 59 312 3.0E-42 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMALA_RS06620 044665e7a486699fcea65e1c449649e3 259 Gene3D G3DSA:3.90.226.10 4 259 1.0E-57 T 29-03-2018 SMALA_RS06620 044665e7a486699fcea65e1c449649e3 259 Pfam PF00378 Enoyl-CoA hydratase/isomerase 20 238 4.4E-49 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 SMALA_RS06620 044665e7a486699fcea65e1c449649e3 259 SUPERFAMILY SSF52096 20 257 2.91E-61 T 29-03-2018 IPR029045 ClpP/crotonase-like domain SMALA_RS21575 2ee35285204ae2993f658f68e35a048f 63 Pfam PF04149 Domain of unknown function (DUF397) 5 55 7.9E-12 T 29-03-2018 IPR007278 Domain of unknown function DUF397 SMALA_RS08085 983e6102a520714775eeda8bef8c8dc0 551 Pfam PF00890 FAD binding domain 6 532 1.6E-110 T 29-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMALA_RS08085 983e6102a520714775eeda8bef8c8dc0 551 SUPERFAMILY SSF51905 3 279 2.35E-35 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS08085 983e6102a520714775eeda8bef8c8dc0 551 SUPERFAMILY SSF51905 487 549 2.35E-35 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS08085 983e6102a520714775eeda8bef8c8dc0 551 PIRSF PIRSF036654 1 550 1.3E-296 T 29-03-2018 IPR014614 Uncharacterised conserved protein UCP036654 GO:0016627|GO:0055114 SMALA_RS08085 983e6102a520714775eeda8bef8c8dc0 551 Gene3D G3DSA:3.50.50.60 1 335 8.9E-39 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS08085 983e6102a520714775eeda8bef8c8dc0 551 Gene3D G3DSA:3.50.50.60 457 548 1.7E-14 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS17625 e3eabad92bccd4fb6989c2ae72dc3132 234 Gene3D G3DSA:1.10.10.10 32 229 2.3E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS17625 e3eabad92bccd4fb6989c2ae72dc3132 234 SUPERFAMILY SSF46894 167 226 8.84E-8 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS32955 78cc4df28dda3703d7befe76f28b8e28 287 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 119 283 1.0E-22 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 SMALA_RS32955 78cc4df28dda3703d7befe76f28b8e28 287 SUPERFAMILY SSF50891 112 282 9.2E-30 T 29-03-2018 IPR029000 Cyclophilin-like domain SMALA_RS32955 78cc4df28dda3703d7befe76f28b8e28 287 Gene3D G3DSA:2.40.100.10 96 287 1.8E-36 T 29-03-2018 IPR029000 Cyclophilin-like domain SMALA_RS26665 98ed6bc8a786dd15fe4df9b88b1b8c87 440 Gene3D G3DSA:1.20.1250.20 21 211 4.4E-24 T 29-03-2018 SMALA_RS26665 98ed6bc8a786dd15fe4df9b88b1b8c87 440 Pfam PF07690 Major Facilitator Superfamily 34 368 1.2E-32 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS26665 98ed6bc8a786dd15fe4df9b88b1b8c87 440 SUPERFAMILY SSF103473 17 401 1.7E-55 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS26665 98ed6bc8a786dd15fe4df9b88b1b8c87 440 Gene3D G3DSA:1.20.1250.20 212 404 8.3E-20 T 29-03-2018 SMALA_RS27255 e15df580e047abe7ee8c07d0c4aa900c 219 Pfam PF08281 Sigma-70, region 4 125 176 1.2E-15 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS27255 e15df580e047abe7ee8c07d0c4aa900c 219 SUPERFAMILY SSF88946 6 97 4.71E-22 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS27255 e15df580e047abe7ee8c07d0c4aa900c 219 Gene3D G3DSA:1.10.1740.10 2 81 7.7E-21 T 29-03-2018 SMALA_RS27255 e15df580e047abe7ee8c07d0c4aa900c 219 Gene3D G3DSA:1.10.10.10 82 183 3.9E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS27255 e15df580e047abe7ee8c07d0c4aa900c 219 SUPERFAMILY SSF88659 118 179 1.48E-15 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS27255 e15df580e047abe7ee8c07d0c4aa900c 219 Pfam PF04542 Sigma-70 region 2 20 88 8.9E-14 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS27255 e15df580e047abe7ee8c07d0c4aa900c 219 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 15 178 8.8E-24 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS11445 bae2daf07b3ea6d380bffc3fd581d3ba 488 Gene3D G3DSA:3.40.605.10 3 270 5.2E-85 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS11445 bae2daf07b3ea6d380bffc3fd581d3ba 488 Gene3D G3DSA:3.40.309.10 271 463 3.0E-68 T 29-03-2018 SMALA_RS11445 bae2daf07b3ea6d380bffc3fd581d3ba 488 Pfam PF00171 Aldehyde dehydrogenase family 22 476 5.6E-153 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS11445 bae2daf07b3ea6d380bffc3fd581d3ba 488 SUPERFAMILY SSF53720 5 480 1.26E-154 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMALA_RS11445 bae2daf07b3ea6d380bffc3fd581d3ba 488 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 252 259 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 SMALA_RS16465 b245facd8befb7455b1bfb360335473f 67 Pfam PF04024 PspC domain 5 59 2.3E-18 T 29-03-2018 IPR007168 Phage shock protein, PspC, N-terminal SMALA_RS42640 e1eabf013250f208755a036218e4f5d2 161 SUPERFAMILY SSF46785 10 113 3.05E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS42640 e1eabf013250f208755a036218e4f5d2 161 Pfam PF12802 MarR family 22 81 3.4E-10 T 29-03-2018 SMALA_RS42640 e1eabf013250f208755a036218e4f5d2 161 Gene3D G3DSA:1.10.10.10 4 154 1.5E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS33410 12d855496ca764f2c58e0850e0d57208 277 Gene3D G3DSA:1.10.10.10 180 274 1.7E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS33410 12d855496ca764f2c58e0850e0d57208 277 SMART SM00418 189 260 8.5E-4 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS33410 12d855496ca764f2c58e0850e0d57208 277 SUPERFAMILY SSF46785 189 261 1.17E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS33410 12d855496ca764f2c58e0850e0d57208 277 Pfam PF12840 Helix-turn-helix domain 191 243 7.4E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS33245 58b95c8bdc51a41ab47f726c0b3fd71c 569 Gene3D G3DSA:3.50.50.60 22 568 8.6E-55 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS33245 58b95c8bdc51a41ab47f726c0b3fd71c 569 SUPERFAMILY SSF51905 504 544 3.02E-43 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS33245 58b95c8bdc51a41ab47f726c0b3fd71c 569 SUPERFAMILY SSF51905 56 387 3.02E-43 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS33245 58b95c8bdc51a41ab47f726c0b3fd71c 569 Pfam PF01593 Flavin containing amine oxidoreductase 64 538 1.1E-45 T 29-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 SMALA_RS33245 58b95c8bdc51a41ab47f726c0b3fd71c 569 SUPERFAMILY SSF54373 367 482 1.11E-27 T 29-03-2018 SMALA_RS39425 c018bd684cf5ad6a160c5529a5bc9531 377 SUPERFAMILY SSF51182 21 303 5.66E-37 T 29-03-2018 IPR011051 RmlC-like cupin domain SMALA_RS39425 c018bd684cf5ad6a160c5529a5bc9531 377 Gene3D G3DSA:2.60.120.10 198 354 6.7E-10 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SMALA_RS39425 c018bd684cf5ad6a160c5529a5bc9531 377 Gene3D G3DSA:2.60.120.10 17 196 3.4E-12 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SMALA_RS24495 b631af468867810751af954c5f27965c 429 SMART SM01119 318 416 1.1E-34 T 29-03-2018 IPR026956 D-serine dehydratase-like domain SMALA_RS24495 b631af468867810751af954c5f27965c 429 SUPERFAMILY SSF51419 59 274 4.58E-22 T 29-03-2018 IPR029066 PLP-binding barrel SMALA_RS24495 b631af468867810751af954c5f27965c 429 Pfam PF14031 Putative serine dehydratase domain 318 414 4.6E-16 T 29-03-2018 IPR026956 D-serine dehydratase-like domain SMALA_RS24495 b631af468867810751af954c5f27965c 429 Gene3D G3DSA:3.20.20.10 59 332 1.7E-30 T 29-03-2018 IPR029066 PLP-binding barrel SMALA_RS22930 f723478f6f8a437bc4935333fbe18d3c 236 SUPERFAMILY SSF50800 9 231 7.85E-55 T 29-03-2018 IPR011037 Pyruvate kinase-like, insert domain SMALA_RS22930 f723478f6f8a437bc4935333fbe18d3c 236 Gene3D G3DSA:2.40.33.20 29 235 1.9E-44 T 29-03-2018 SMALA_RS22930 f723478f6f8a437bc4935333fbe18d3c 236 Pfam PF03473 MOSC domain 71 184 1.3E-23 T 29-03-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 SMALA_RS00885 a4516c679fe72168c53b7b056bc9c077 198 Gene3D G3DSA:1.10.260.40 2 71 3.1E-18 T 29-03-2018 SMALA_RS00885 a4516c679fe72168c53b7b056bc9c077 198 Pfam PF07883 Cupin domain 122 182 3.3E-16 T 29-03-2018 IPR013096 Cupin 2, conserved barrel SMALA_RS00885 a4516c679fe72168c53b7b056bc9c077 198 SMART SM00530 16 71 9.4E-17 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS00885 a4516c679fe72168c53b7b056bc9c077 198 SUPERFAMILY SSF51182 69 181 3.47E-21 T 29-03-2018 IPR011051 RmlC-like cupin domain SMALA_RS00885 a4516c679fe72168c53b7b056bc9c077 198 Gene3D G3DSA:2.60.120.10 72 195 1.7E-22 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SMALA_RS00885 a4516c679fe72168c53b7b056bc9c077 198 Pfam PF01381 Helix-turn-helix 18 71 2.3E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS00885 a4516c679fe72168c53b7b056bc9c077 198 SUPERFAMILY SSF47413 7 76 3.94E-18 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS41380 3f0fb68576195a44f6180d739dc83237 201 Gene3D G3DSA:1.10.10.60 3 62 7.4E-21 T 29-03-2018 SMALA_RS41380 3f0fb68576195a44f6180d739dc83237 201 Gene3D G3DSA:1.10.357.10 63 190 6.8E-16 T 29-03-2018 SMALA_RS41380 3f0fb68576195a44f6180d739dc83237 201 SUPERFAMILY SSF46689 8 81 2.29E-18 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS41380 3f0fb68576195a44f6180d739dc83237 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 2.7E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS41380 3f0fb68576195a44f6180d739dc83237 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 2.7E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS41380 3f0fb68576195a44f6180d739dc83237 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 64 5.7E-16 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS13875 99a3a5d759ca9f1e6c6736264deb9853 295 Gene3D G3DSA:3.20.20.70 2 295 5.8E-84 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS13875 99a3a5d759ca9f1e6c6736264deb9853 295 SUPERFAMILY SSF51569 29 281 4.03E-35 T 29-03-2018 SMALA_RS14680 88ff9aa6f22e0c1fea09eab1e80809df 156 SUPERFAMILY SSF54637 22 122 1.06E-14 T 29-03-2018 IPR029069 HotDog domain SMALA_RS14680 88ff9aa6f22e0c1fea09eab1e80809df 156 Gene3D G3DSA:3.10.129.10 9 129 4.6E-18 T 29-03-2018 SMALA_RS00820 17355f994c45e6d68deec2c5b522a4be 269 Gene3D G3DSA:1.20.5.370 12 47 0.001 T 29-03-2018 SMALA_RS00820 17355f994c45e6d68deec2c5b522a4be 269 Gene3D G3DSA:1.10.10.10 186 267 6.8E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS04680 fc5fafdd489efba4a112be21f5637982 805 Gene3D G3DSA:2.60.40.1180 688 805 5.3E-33 T 29-03-2018 SMALA_RS04680 fc5fafdd489efba4a112be21f5637982 805 Gene3D G3DSA:2.70.98.50 31 324 3.0E-79 T 29-03-2018 SMALA_RS04680 fc5fafdd489efba4a112be21f5637982 805 Pfam PF14498 Glycosyl hydrolase family 65, N-terminal domain 48 284 1.4E-73 T 29-03-2018 IPR027414 Glycosyl hydrolase family 95, N-terminal domain KEGG: 00511+3.2.1.51 SMALA_RS04680 fc5fafdd489efba4a112be21f5637982 805 SUPERFAMILY SSF48208 290 750 4.71E-81 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 SMALA_RS04680 fc5fafdd489efba4a112be21f5637982 805 PIRSF PIRSF007663 20 794 5.2E-277 T 29-03-2018 IPR016518 Alpha-L-fucosidase GO:0004560 KEGG: 00511+3.2.1.51 SMALA_RS04680 fc5fafdd489efba4a112be21f5637982 805 Gene3D G3DSA:1.50.10.10 356 645 4.0E-74 T 29-03-2018 SMALA_RS42260 0a64401eca76df5a338891291f93fe0d 212 Pfam PF00694 Aconitase C-terminal domain 25 122 1.4E-18 T 29-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS42260 0a64401eca76df5a338891291f93fe0d 212 SUPERFAMILY SSF52016 9 186 1.16E-40 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel SMALA_RS42260 0a64401eca76df5a338891291f93fe0d 212 Gene3D G3DSA:3.20.19.10 5 180 9.1E-32 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel SMALA_RS39250 afbfb3bdbb67581f21da646778772351 284 Gene3D G3DSA:3.40.50.1820 5 252 9.8E-36 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS39250 afbfb3bdbb67581f21da646778772351 284 SUPERFAMILY SSF53474 3 249 7.75E-51 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS39250 afbfb3bdbb67581f21da646778772351 284 SMART SM00824 Thioesterase 26 249 8.7E-4 T 29-03-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 SMALA_RS39250 afbfb3bdbb67581f21da646778772351 284 Pfam PF00975 Thioesterase domain 25 247 5.4E-45 T 29-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 SMALA_RS31430 01a7b0847b9651307a9ce5a88511e99d 415 Hamap MF_00742 Formyl-CoA:oxalate CoA-transferase [frc]. 7 415 63.539 T 29-03-2018 IPR017659 Formyl-CoA:oxalate CoA-transferase GO:0008152|GO:0033608 MetaCyc: PWY-6695 SMALA_RS31430 01a7b0847b9651307a9ce5a88511e99d 415 Gene3D G3DSA:3.40.50.10540 5 415 7.2E-120 T 29-03-2018 IPR023606 CoA-transferase family III domain SMALA_RS31430 01a7b0847b9651307a9ce5a88511e99d 415 SUPERFAMILY SSF89796 10 415 1.19E-116 T 29-03-2018 IPR023606 CoA-transferase family III domain SMALA_RS31430 01a7b0847b9651307a9ce5a88511e99d 415 TIGRFAM TIGR03253 oxalate_frc: formyl-CoA transferase 9 415 1.5E-208 T 29-03-2018 IPR017659 Formyl-CoA:oxalate CoA-transferase GO:0008152|GO:0033608 MetaCyc: PWY-6695 SMALA_RS31430 01a7b0847b9651307a9ce5a88511e99d 415 Pfam PF02515 CoA-transferase family III 11 391 5.4E-102 T 29-03-2018 IPR003673 CoA-transferase family III GO:0003824 SMALA_RS06935 07fcecaa8ecc6e2249be445156e0af47 109 Gene3D G3DSA:3.40.30.10 23 98 3.0E-18 T 29-03-2018 SMALA_RS06935 07fcecaa8ecc6e2249be445156e0af47 109 SUPERFAMILY SSF52833 28 96 2.54E-14 T 29-03-2018 IPR012336 Thioredoxin-like fold SMALA_RS06935 07fcecaa8ecc6e2249be445156e0af47 109 Pfam PF00085 Thioredoxin 40 96 1.8E-9 T 29-03-2018 IPR013766 Thioredoxin domain GO:0045454 SMALA_RS37260 02d8e50a69f288b18df225e2506ea9e2 425 Pfam PF01494 FAD binding domain 4 352 1.8E-51 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 SMALA_RS37260 02d8e50a69f288b18df225e2506ea9e2 425 Gene3D G3DSA:3.50.50.60 2 368 4.9E-46 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS37260 02d8e50a69f288b18df225e2506ea9e2 425 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 311 327 4.1E-18 T 29-03-2018 SMALA_RS37260 02d8e50a69f288b18df225e2506ea9e2 425 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 4.1E-18 T 29-03-2018 SMALA_RS37260 02d8e50a69f288b18df225e2506ea9e2 425 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 158 173 4.1E-18 T 29-03-2018 SMALA_RS37260 02d8e50a69f288b18df225e2506ea9e2 425 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 296 311 4.1E-18 T 29-03-2018 SMALA_RS37260 02d8e50a69f288b18df225e2506ea9e2 425 SUPERFAMILY SSF51905 283 371 3.76E-52 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS37260 02d8e50a69f288b18df225e2506ea9e2 425 SUPERFAMILY SSF51905 5 179 3.76E-52 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS37815 ada8fc5373f864721ed13001661840f8 68 Gene3D G3DSA:3.30.70.20 1 65 4.6E-7 T 29-03-2018 SMALA_RS37815 ada8fc5373f864721ed13001661840f8 68 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 4.7E-6 T 29-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 SMALA_RS37815 ada8fc5373f864721ed13001661840f8 68 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 4.7E-6 T 29-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 SMALA_RS37815 ada8fc5373f864721ed13001661840f8 68 PRINTS PR00352 3Fe-4S ferredoxin signature 48 60 4.7E-6 T 29-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 SMALA_RS37815 ada8fc5373f864721ed13001661840f8 68 SUPERFAMILY SSF54862 2 64 2.44E-12 T 29-03-2018 SMALA_RS37815 ada8fc5373f864721ed13001661840f8 68 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 6 61 1.4E-11 T 29-03-2018 SMALA_RS41310 079120b6a76eef0adeb824415f7da13c 563 Pfam PF13556 PucR C-terminal helix-turn-helix domain 503 561 5.3E-23 T 29-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain SMALA_RS41310 079120b6a76eef0adeb824415f7da13c 563 Gene3D G3DSA:3.30.450.40 130 270 6.7E-9 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS41310 079120b6a76eef0adeb824415f7da13c 563 Gene3D G3DSA:1.10.10.60 489 539 6.7E-8 T 29-03-2018 SMALA_RS20810 4e9b0ecda8f49b19bc93dcaa05010bfd 336 SUPERFAMILY SSF111331 3 121 3.49E-6 T 29-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain SMALA_RS20810 4e9b0ecda8f49b19bc93dcaa05010bfd 336 Gene3D G3DSA:3.40.50.10330 1 121 1.4E-9 T 29-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 SMALA_RS27385 a7cce3e57c64cf4bfd708eeb205163d2 544 SUPERFAMILY SSF55486 219 543 1.21E-81 T 29-03-2018 SMALA_RS27385 a7cce3e57c64cf4bfd708eeb205163d2 544 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 369 543 1.6E-54 T 29-03-2018 IPR001570 Peptidase M4, C-terminal GO:0004222 SMALA_RS27385 a7cce3e57c64cf4bfd708eeb205163d2 544 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 321 341 3.6E-19 T 29-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 SMALA_RS27385 a7cce3e57c64cf4bfd708eeb205163d2 544 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 445 461 3.6E-19 T 29-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 SMALA_RS27385 a7cce3e57c64cf4bfd708eeb205163d2 544 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 357 373 3.6E-19 T 29-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 SMALA_RS27385 a7cce3e57c64cf4bfd708eeb205163d2 544 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 378 389 3.6E-19 T 29-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 SMALA_RS27385 a7cce3e57c64cf4bfd708eeb205163d2 544 Pfam PF07504 Fungalysin/Thermolysin Propeptide Motif 79 126 1.4E-17 T 29-03-2018 IPR011096 FTP domain SMALA_RS27385 a7cce3e57c64cf4bfd708eeb205163d2 544 Gene3D G3DSA:1.10.390.10 371 544 5.6E-49 T 29-03-2018 SMALA_RS27385 a7cce3e57c64cf4bfd708eeb205163d2 544 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 219 366 6.2E-49 T 29-03-2018 IPR013856 Peptidase M4 domain GO:0004222 SMALA_RS27385 a7cce3e57c64cf4bfd708eeb205163d2 544 Gene3D G3DSA:3.10.170.10 218 370 3.9E-48 T 29-03-2018 SMALA_RS25175 2ad2a90a1a71b594fbd1aa359c3dfc3d 509 Gene3D G3DSA:3.40.50.980 174 322 1.6E-28 T 29-03-2018 SMALA_RS25175 2ad2a90a1a71b594fbd1aa359c3dfc3d 509 Gene3D G3DSA:2.30.38.10 323 406 1.1E-28 T 29-03-2018 SMALA_RS25175 2ad2a90a1a71b594fbd1aa359c3dfc3d 509 SUPERFAMILY SSF56801 8 507 7.98E-121 T 29-03-2018 SMALA_RS25175 2ad2a90a1a71b594fbd1aa359c3dfc3d 509 Gene3D G3DSA:3.40.50.980 6 173 8.0E-27 T 29-03-2018 SMALA_RS25175 2ad2a90a1a71b594fbd1aa359c3dfc3d 509 Pfam PF13193 AMP-binding enzyme C-terminal domain 422 497 2.3E-14 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS25175 2ad2a90a1a71b594fbd1aa359c3dfc3d 509 Pfam PF00501 AMP-binding enzyme 22 413 7.1E-81 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS25175 2ad2a90a1a71b594fbd1aa359c3dfc3d 509 Gene3D G3DSA:3.30.300.30 407 509 4.7E-21 T 29-03-2018 SMALA_RS24450 e1fc8f6f654a79fac41cb7a4bfe8fa34 537 Gene3D G3DSA:3.40.190.10 188 317 1.8E-25 T 29-03-2018 SMALA_RS24450 e1fc8f6f654a79fac41cb7a4bfe8fa34 537 Gene3D G3DSA:3.90.76.10 88 187 3.8E-25 T 29-03-2018 SMALA_RS24450 e1fc8f6f654a79fac41cb7a4bfe8fa34 537 SUPERFAMILY SSF53850 60 527 5.07E-103 T 29-03-2018 SMALA_RS24450 e1fc8f6f654a79fac41cb7a4bfe8fa34 537 PIRSF PIRSF002741 27 531 7.3E-68 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 SMALA_RS24450 e1fc8f6f654a79fac41cb7a4bfe8fa34 537 Gene3D G3DSA:3.10.105.10 318 507 1.8E-38 T 29-03-2018 SMALA_RS24450 e1fc8f6f654a79fac41cb7a4bfe8fa34 537 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 107 443 1.5E-62 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain SMALA_RS29815 dac1935d60f857210ffaf2de6cfc625e 348 Gene3D G3DSA:2.120.10.70 2 238 2.2E-27 T 29-03-2018 SMALA_RS29815 dac1935d60f857210ffaf2de6cfc625e 348 Gene3D G3DSA:2.120.10.70 239 346 0.019 T 29-03-2018 SMALA_RS29815 dac1935d60f857210ffaf2de6cfc625e 348 SUPERFAMILY SSF89372 8 305 5.62E-17 T 29-03-2018 SMALA_RS31605 ec2fd2c1eaca9d54abe7e38ad0680c82 418 Gene3D G3DSA:1.10.4100.10 1 299 1.6E-40 T 29-03-2018 SMALA_RS31605 ec2fd2c1eaca9d54abe7e38ad0680c82 418 Pfam PF03972 MmgE/PrpD family 36 356 1.2E-38 T 29-03-2018 IPR005656 MmgE/PrpD GO:0016829 SMALA_RS31605 ec2fd2c1eaca9d54abe7e38ad0680c82 418 SUPERFAMILY SSF103378 26 359 1.19E-42 T 29-03-2018 IPR005656 MmgE/PrpD GO:0016829 SMALA_RS06355 24a1591137f5fc3b00fd69d2d6507c93 760 Pfam PF14508 Glycosyl-hydrolase 97 N-terminal 121 370 2.5E-61 T 29-03-2018 IPR029486 Glycosyl-hydrolase 97, N-terminal domain SMALA_RS06355 24a1591137f5fc3b00fd69d2d6507c93 760 Gene3D G3DSA:2.70.98.10 118 366 4.8E-70 T 29-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 SMALA_RS06355 24a1591137f5fc3b00fd69d2d6507c93 760 Gene3D G3DSA:3.20.20.70 367 660 2.2E-82 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS06355 24a1591137f5fc3b00fd69d2d6507c93 760 SUPERFAMILY SSF51445 373 642 5.62E-10 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS06355 24a1591137f5fc3b00fd69d2d6507c93 760 Gene3D G3DSA:2.60.40.1180 661 760 8.9E-31 T 29-03-2018 SMALA_RS06355 24a1591137f5fc3b00fd69d2d6507c93 760 Pfam PF14509 Glycosyl-hydrolase 97 C-terminal, oligomerisation 659 755 1.1E-27 T 29-03-2018 IPR029483 Glycosyl-hydrolase 97, C-terminal oligomerisation domain SMALA_RS06355 24a1591137f5fc3b00fd69d2d6507c93 760 Pfam PF10566 Glycoside hydrolase 97 375 656 7.9E-91 T 29-03-2018 IPR019563 Glycosyl-hydrolase 97, catalytic domain SMALA_RS31300 c35df43697a6fdea50480f7e22764306 294 Gene3D G3DSA:3.10.20.10 28 120 2.8E-30 T 29-03-2018 SMALA_RS31300 c35df43697a6fdea50480f7e22764306 294 Hamap MF_00187 Sulfurtransferase FdhD [fdhD]. 2 286 34.402 T 29-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 SMALA_RS31300 c35df43697a6fdea50480f7e22764306 294 SUPERFAMILY SSF53927 4 285 1.2E-76 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 SMALA_RS31300 c35df43697a6fdea50480f7e22764306 294 Pfam PF02634 FdhD/NarQ family 26 285 8.1E-79 T 29-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 SMALA_RS31300 c35df43697a6fdea50480f7e22764306 294 PIRSF PIRSF015626 1 289 4.9E-86 T 29-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 SMALA_RS31300 c35df43697a6fdea50480f7e22764306 294 Gene3D G3DSA:3.40.140.10 150 290 6.8E-56 T 29-03-2018 SMALA_RS00915 02ca752e274fac0ac4459f1ebbee049f 339 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 134 332 2.6E-29 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS00915 02ca752e274fac0ac4459f1ebbee049f 339 SUPERFAMILY SSF161098 111 317 1.57E-13 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS00915 02ca752e274fac0ac4459f1ebbee049f 339 Gene3D G3DSA:1.10.3720.10 14 321 1.8E-34 T 29-03-2018 SMALA_RS42940 875f6661c80c3e31c9d94910d73f692e 148 Pfam PF05331 Protein of unknown function (DUF742) 38 148 8.4E-36 T 29-03-2018 IPR007995 Protein of unknown function DUF742 SMALA_RS01095 fdba8d273da9e06f1435ecc367097a98 197 Gene3D G3DSA:1.10.3300.10 14 193 2.5E-25 T 29-03-2018 IPR023286 ABATE domain SMALA_RS01095 fdba8d273da9e06f1435ecc367097a98 197 Pfam PF11706 CGNR zinc finger 152 189 2.7E-9 T 29-03-2018 IPR021005 Zinc finger, CGNR SMALA_RS01095 fdba8d273da9e06f1435ecc367097a98 197 SUPERFAMILY SSF160904 23 189 1.24E-28 T 29-03-2018 SMALA_RS14675 9a26caf3e626465bd8ea85d3dbe1a5a3 182 SUPERFAMILY SSF54637 1 146 2.26E-26 T 29-03-2018 IPR029069 HotDog domain SMALA_RS14675 9a26caf3e626465bd8ea85d3dbe1a5a3 182 Pfam PF07977 FabA-like domain 11 140 1.3E-12 T 29-03-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 SMALA_RS14675 9a26caf3e626465bd8ea85d3dbe1a5a3 182 Gene3D G3DSA:3.10.129.10 1 150 1.6E-35 T 29-03-2018 SMALA_RS07985 63032556351d779c2ea4ea061abc9a67 368 Pfam PF00534 Glycosyl transferases group 1 177 338 2.1E-29 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 SMALA_RS07985 63032556351d779c2ea4ea061abc9a67 368 SUPERFAMILY SSF53756 17 363 1.88E-55 T 29-03-2018 SMALA_RS07985 63032556351d779c2ea4ea061abc9a67 368 Gene3D G3DSA:3.40.50.2000 55 342 5.3E-37 T 29-03-2018 SMALA_RS18310 9d969f9869e9becd570b91b4381330ce 232 Pfam PF01569 PAP2 superfamily 99 207 1.1E-16 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMALA_RS18310 9d969f9869e9becd570b91b4381330ce 232 SMART SM00014 99 208 1.1E-6 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMALA_RS18310 9d969f9869e9becd570b91b4381330ce 232 Gene3D G3DSA:1.20.144.10 28 223 1.6E-18 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMALA_RS18310 9d969f9869e9becd570b91b4381330ce 232 SUPERFAMILY SSF48317 20 211 1.44E-26 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMALA_RS26950 a3b22503097a5b72bbf750f5035eed09 190 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 8 182 2.3E-46 T 29-03-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 SMALA_RS26950 a3b22503097a5b72bbf750f5035eed09 190 Gene3D G3DSA:1.20.1200.10 16 190 1.2E-51 T 29-03-2018 SMALA_RS26950 a3b22503097a5b72bbf750f5035eed09 190 Pfam PF01923 Cobalamin adenosyltransferase 7 174 2.8E-51 T 29-03-2018 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 SMALA_RS26950 a3b22503097a5b72bbf750f5035eed09 190 SUPERFAMILY SSF89028 6 185 3.14E-52 T 29-03-2018 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 SMALA_RS26950 a3b22503097a5b72bbf750f5035eed09 190 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 13 184 6.0E-67 T 29-03-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 SMALA_RS31050 c4d1e3c667ab24bccaa388cc47b3aa16 384 Gene3D G3DSA:3.60.15.10 120 380 7.9E-52 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS31050 c4d1e3c667ab24bccaa388cc47b3aa16 384 Pfam PF12706 Beta-lactamase superfamily domain 147 341 4.5E-47 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS31050 c4d1e3c667ab24bccaa388cc47b3aa16 384 SUPERFAMILY SSF56281 126 358 2.49E-38 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS31050 c4d1e3c667ab24bccaa388cc47b3aa16 384 SMART SM00849 134 340 0.0053 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS34610 86066528db9f690d8e6537282c378809 408 Gene3D G3DSA:3.40.640.10 35 287 4.8E-45 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS34610 86066528db9f690d8e6537282c378809 408 Gene3D G3DSA:3.90.1150.10 321 405 9.2E-22 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS34610 86066528db9f690d8e6537282c378809 408 Gene3D G3DSA:3.90.1150.10 288 320 6.2E-5 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS34610 86066528db9f690d8e6537282c378809 408 PIRSF PIRSF001434 25 405 6.9E-112 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 SMALA_RS34610 86066528db9f690d8e6537282c378809 408 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 39 402 1.5E-88 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 SMALA_RS34610 86066528db9f690d8e6537282c378809 408 SUPERFAMILY SSF53383 75 403 4.9E-78 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS15215 1594a7c7f8890e04f74b6d560d63ecb6 515 Gene3D G3DSA:1.10.10.10 432 505 3.3E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS15215 1594a7c7f8890e04f74b6d560d63ecb6 515 Pfam PF13148 Protein of unknown function (DUF3987) 63 426 3.2E-101 T 29-03-2018 IPR025048 Protein of unknown function DUF3987) SMALA_RS25305 d410e1898d978cf6cc6490e47f1597d3 468 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 11 410 5.1E-79 T 29-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 SMALA_RS25305 d410e1898d978cf6cc6490e47f1597d3 468 Gene3D G3DSA:1.20.1250.20 3 197 1.8E-33 T 29-03-2018 SMALA_RS25305 d410e1898d978cf6cc6490e47f1597d3 468 Gene3D G3DSA:1.20.1250.20 250 461 1.0E-25 T 29-03-2018 SMALA_RS25305 d410e1898d978cf6cc6490e47f1597d3 468 SUPERFAMILY SSF103473 4 197 6.67E-68 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS25305 d410e1898d978cf6cc6490e47f1597d3 468 SUPERFAMILY SSF103473 246 456 6.67E-68 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS25305 d410e1898d978cf6cc6490e47f1597d3 468 PRINTS PR01036 Tetracycline resistance protein TetB signature 200 218 6.4E-10 T 29-03-2018 SMALA_RS25305 d410e1898d978cf6cc6490e47f1597d3 468 PRINTS PR01036 Tetracycline resistance protein TetB signature 14 38 6.4E-10 T 29-03-2018 SMALA_RS25305 d410e1898d978cf6cc6490e47f1597d3 468 PRINTS PR01036 Tetracycline resistance protein TetB signature 105 125 6.4E-10 T 29-03-2018 SMALA_RS25305 d410e1898d978cf6cc6490e47f1597d3 468 PRINTS PR01036 Tetracycline resistance protein TetB signature 135 159 6.4E-10 T 29-03-2018 SMALA_RS25305 d410e1898d978cf6cc6490e47f1597d3 468 Pfam PF07690 Major Facilitator Superfamily 15 408 2.8E-53 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS06680 127467ad5de59375e0cc5d943978c2a9 348 SUPERFAMILY SSF51430 14 328 5.24E-86 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS06680 127467ad5de59375e0cc5d943978c2a9 348 Gene3D G3DSA:3.20.20.100 16 333 1.1E-81 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS06680 127467ad5de59375e0cc5d943978c2a9 348 Pfam PF00248 Aldo/keto reductase family 29 328 1.4E-66 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS09430 12da9bd1d6af8966723a01d36d89e8cd 608 Gene3D G3DSA:3.60.10.10 305 607 1.0E-33 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMALA_RS09430 12da9bd1d6af8966723a01d36d89e8cd 608 SUPERFAMILY SSF56219 305 606 6.48E-32 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMALA_RS09430 12da9bd1d6af8966723a01d36d89e8cd 608 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 308 599 7.8E-11 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMALA_RS01035 729bf65e4ba8b78394ea47ddaf7751a0 218 ProDom PD068376 ORF2 SECRETED GLNII PRECURSOR SIGNAL 35 218 1.0E-47 T 29-03-2018 SMALA_RS20285 d8bdc1f8a5a37c61aa9293ab013549e8 222 Pfam PF11303 Protein of unknown function (DUF3105) 92 214 1.6E-45 T 29-03-2018 IPR021454 Protein of unknown function DUF3105 SMALA_RS20285 d8bdc1f8a5a37c61aa9293ab013549e8 222 Gene3D G3DSA:1.20.5.210 78 153 0.013 T 29-03-2018 IPR004205 Cytochrome b-c1 complex subunit 8 GO:0008121 Reactome: R-HSA-611105 SMALA_RS39185 d26b34b44407781f0d9f87067e44e7ba 332 Gene3D G3DSA:3.10.129.10 3 204 0.019 T 29-03-2018 SMALA_RS39185 d26b34b44407781f0d9f87067e44e7ba 332 TIGRFAM TIGR04098 biosyn_clust_1: biosynthesis cluster domain 24 315 3.1E-88 T 29-03-2018 SMALA_RS39185 d26b34b44407781f0d9f87067e44e7ba 332 Gene3D G3DSA:3.10.129.10 220 292 0.0019 T 29-03-2018 SMALA_RS39185 d26b34b44407781f0d9f87067e44e7ba 332 SUPERFAMILY SSF54637 222 285 3.32E-6 T 29-03-2018 IPR029069 HotDog domain SMALA_RS21465 e048f342c5d2d67c80d985b3133b07ac 158 Gene3D G3DSA:1.10.10.10 6 88 1.4E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS21465 e048f342c5d2d67c80d985b3133b07ac 158 Pfam PF01475 Ferric uptake regulator family 12 113 1.6E-22 T 29-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 SMALA_RS21465 e048f342c5d2d67c80d985b3133b07ac 158 SUPERFAMILY SSF46785 6 134 8.52E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS23705 a9b389759e4ba21114910a156e1cdc13 191 Pfam PF00501 AMP-binding enzyme 29 165 3.0E-18 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS23705 a9b389759e4ba21114910a156e1cdc13 191 Gene3D G3DSA:3.40.50.980 25 172 5.7E-27 T 29-03-2018 SMALA_RS23705 a9b389759e4ba21114910a156e1cdc13 191 SUPERFAMILY SSF56801 29 187 8.9E-31 T 29-03-2018 SMALA_RS00045 baec1e4dbeac964294c825b072d5b43a 216 Gene3D G3DSA:3.40.140.10 52 194 0.001 T 29-03-2018 SMALA_RS02840 fb2fd0b7b845425369c0de5dd1ba55eb 148 Gene3D G3DSA:1.10.10.10 2 147 1.1E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS02840 fb2fd0b7b845425369c0de5dd1ba55eb 148 SUPERFAMILY SSF46785 3 136 3.69E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS02840 fb2fd0b7b845425369c0de5dd1ba55eb 148 Pfam PF02082 Transcriptional regulator 4 83 2.2E-17 T 29-03-2018 IPR000944 Transcription regulator Rrf2-type SMALA_RS27600 da84d6765e714b309cf606b4a9889f3b 260 SMART SM00644 109 238 9.1E-39 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 SMALA_RS27600 da84d6765e714b309cf606b4a9889f3b 260 SUPERFAMILY SSF55846 108 253 7.72E-41 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 SMALA_RS27600 da84d6765e714b309cf606b4a9889f3b 260 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 118 238 1.7E-29 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 SMALA_RS27600 da84d6765e714b309cf606b4a9889f3b 260 Gene3D G3DSA:3.40.80.10 101 255 7.7E-39 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 SMALA_RS27235 f1fca737475024024f61375e38211985 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 56 1.5E-13 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS27235 f1fca737475024024f61375e38211985 202 SUPERFAMILY SSF46689 2 77 1.39E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS27235 f1fca737475024024f61375e38211985 202 Gene3D G3DSA:1.10.10.60 1 44 1.0E-16 T 29-03-2018 SMALA_RS27235 f1fca737475024024f61375e38211985 202 Gene3D G3DSA:1.10.260.40 45 66 8.5E-4 T 29-03-2018 SMALA_RS27235 f1fca737475024024f61375e38211985 202 Gene3D G3DSA:1.10.357.10 67 201 3.2E-26 T 29-03-2018 SMALA_RS14235 22514a61887c97359ca2179fd1f4072a 173 Gene3D G3DSA:3.40.50.620 14 172 4.6E-22 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS14235 22514a61887c97359ca2179fd1f4072a 173 Pfam PF00582 Universal stress protein family 40 173 1.1E-22 T 29-03-2018 IPR006016 UspA GO:0006950 SMALA_RS14235 22514a61887c97359ca2179fd1f4072a 173 SUPERFAMILY SSF52402 40 173 1.26E-21 T 29-03-2018 SMALA_RS14235 22514a61887c97359ca2179fd1f4072a 173 PRINTS PR01438 Universal stress protein signature 37 55 1.9E-6 T 29-03-2018 IPR006015 Universal stress protein A SMALA_RS14235 22514a61887c97359ca2179fd1f4072a 173 PRINTS PR01438 Universal stress protein signature 151 173 1.9E-6 T 29-03-2018 IPR006015 Universal stress protein A SMALA_RS09860 bdc9bd208f6d9aafe06e550376579a48 598 Pfam PF00149 Calcineurin-like phosphoesterase 44 291 9.5E-11 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 SMALA_RS09860 bdc9bd208f6d9aafe06e550376579a48 598 ProSitePatterns PS00786 5'-nucleotidase signature 2. 139 150 - T 29-03-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 SMALA_RS09860 bdc9bd208f6d9aafe06e550376579a48 598 Gene3D G3DSA:3.90.780.10 367 595 8.8E-46 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 SMALA_RS09860 bdc9bd208f6d9aafe06e550376579a48 598 PRINTS PR01607 Apyrase family signature 526 545 1.4E-24 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 SMALA_RS09860 bdc9bd208f6d9aafe06e550376579a48 598 PRINTS PR01607 Apyrase family signature 435 458 1.4E-24 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 SMALA_RS09860 bdc9bd208f6d9aafe06e550376579a48 598 PRINTS PR01607 Apyrase family signature 42 60 1.4E-24 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 SMALA_RS09860 bdc9bd208f6d9aafe06e550376579a48 598 PRINTS PR01607 Apyrase family signature 274 297 1.4E-24 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 SMALA_RS09860 bdc9bd208f6d9aafe06e550376579a48 598 PRINTS PR01607 Apyrase family signature 307 327 1.4E-24 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 SMALA_RS09860 bdc9bd208f6d9aafe06e550376579a48 598 PRINTS PR01607 Apyrase family signature 241 258 1.4E-24 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 SMALA_RS09860 bdc9bd208f6d9aafe06e550376579a48 598 SUPERFAMILY SSF56300 39 371 9.28E-75 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SMALA_RS09860 bdc9bd208f6d9aafe06e550376579a48 598 SUPERFAMILY SSF55816 369 584 2.22E-41 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 SMALA_RS09860 bdc9bd208f6d9aafe06e550376579a48 598 Gene3D G3DSA:3.60.21.10 33 366 9.8E-72 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SMALA_RS09860 bdc9bd208f6d9aafe06e550376579a48 598 Pfam PF02872 5'-nucleotidase, C-terminal domain 372 552 3.1E-29 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 SMALA_RS12635 32024fa5856886079ad56291b4c70028 426 Gene3D G3DSA:1.50.10.10 1 420 1.2E-83 T 29-03-2018 SMALA_RS12635 32024fa5856886079ad56291b4c70028 426 SUPERFAMILY SSF48208 7 420 2.81E-71 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 SMALA_RS20605 6ade4017cca55d9f972176a224a51488 117 Gene3D G3DSA:1.10.150.130 18 94 4.6E-4 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal SMALA_RS35180 d24c413712ba58a75ca6c640ec7a4e8b 255 SUPERFAMILY SSF53335 32 210 1.66E-32 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS35180 d24c413712ba58a75ca6c640ec7a4e8b 255 Pfam PF08241 Methyltransferase domain 53 145 1.3E-20 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 SMALA_RS35180 d24c413712ba58a75ca6c640ec7a4e8b 255 Gene3D G3DSA:3.40.50.150 18 235 5.5E-29 T 29-03-2018 SMALA_RS38440 4ec104bcc5b943cf6c1e36a36ac3a500 201 Gene3D G3DSA:1.10.10.60 2 64 4.2E-16 T 29-03-2018 SMALA_RS38440 4ec104bcc5b943cf6c1e36a36ac3a500 201 SUPERFAMILY SSF46689 12 90 1.13E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS38440 4ec104bcc5b943cf6c1e36a36ac3a500 201 Gene3D G3DSA:1.10.357.10 65 199 4.9E-26 T 29-03-2018 SMALA_RS38440 4ec104bcc5b943cf6c1e36a36ac3a500 201 SUPERFAMILY SSF48498 88 198 2.13E-11 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS38440 4ec104bcc5b943cf6c1e36a36ac3a500 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 3.5E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS38440 4ec104bcc5b943cf6c1e36a36ac3a500 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 3.5E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS38440 4ec104bcc5b943cf6c1e36a36ac3a500 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 66 7.5E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS43145 605a10b83e05cee68f0abda4d6611f0e 145 Pfam PF14216 Domain of unknown function (DUF4326) 42 125 6.4E-21 T 29-03-2018 IPR025475 Protein of unknown function DUF4326) SMALA_RS22800 49a7f1093e6d76a49f597a0396f1b78c 407 Gene3D G3DSA:3.40.50.1820 81 394 2.9E-44 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS22800 49a7f1093e6d76a49f597a0396f1b78c 407 SUPERFAMILY SSF53474 113 389 1.09E-48 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS22800 49a7f1093e6d76a49f597a0396f1b78c 407 Pfam PF00561 alpha/beta hydrolase fold 123 379 7.4E-20 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS35335 b8f03ed98a4172ce1b6305cefb656eb1 633 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 366 626 7.0E-47 T 29-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 SMALA_RS35335 b8f03ed98a4172ce1b6305cefb656eb1 633 Gene3D G3DSA:3.40.50.1820 5 395 2.2E-33 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS35335 b8f03ed98a4172ce1b6305cefb656eb1 633 SUPERFAMILY SSF49785 398 628 2.55E-51 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS35335 b8f03ed98a4172ce1b6305cefb656eb1 633 Gene3D G3DSA:2.60.120.260 396 631 8.9E-60 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS35335 b8f03ed98a4172ce1b6305cefb656eb1 633 SUPERFAMILY SSF53474 226 399 9.12E-41 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS35335 b8f03ed98a4172ce1b6305cefb656eb1 633 SUPERFAMILY SSF53474 26 192 9.12E-41 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS35335 b8f03ed98a4172ce1b6305cefb656eb1 633 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 36 628 1.4E-100 T 29-03-2018 IPR005674 CocE/Serine esterase GO:0016787 SMALA_RS35335 b8f03ed98a4172ce1b6305cefb656eb1 633 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 40 320 2.5E-56 T 29-03-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 SMALA_RS35335 b8f03ed98a4172ce1b6305cefb656eb1 633 SMART SM00939 351 627 2.5E-74 T 29-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 SMALA_RS41740 ae0f28f5f4a803e754880f4636ffdb36 275 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 236 254 - T 29-03-2018 IPR018511 Hemolysin-type calcium-binding conserved site SMALA_RS41740 ae0f28f5f4a803e754880f4636ffdb36 275 SUPERFAMILY SSF51120 52 102 1.07E-7 T 29-03-2018 IPR011049 Serralysin-like metalloprotease, C-terminal SMALA_RS41740 ae0f28f5f4a803e754880f4636ffdb36 275 SUPERFAMILY SSF51120 130 188 1.07E-7 T 29-03-2018 IPR011049 Serralysin-like metalloprotease, C-terminal SMALA_RS41740 ae0f28f5f4a803e754880f4636ffdb36 275 PRINTS PR00313 NodO calcium binding signature 240 249 1.5E-8 T 29-03-2018 SMALA_RS41740 ae0f28f5f4a803e754880f4636ffdb36 275 PRINTS PR00313 NodO calcium binding signature 165 173 1.5E-8 T 29-03-2018 SMALA_RS41740 ae0f28f5f4a803e754880f4636ffdb36 275 PRINTS PR00313 NodO calcium binding signature 147 158 1.5E-8 T 29-03-2018 SMALA_RS41740 ae0f28f5f4a803e754880f4636ffdb36 275 PRINTS PR00313 NodO calcium binding signature 213 221 1.5E-8 T 29-03-2018 SMALA_RS41740 ae0f28f5f4a803e754880f4636ffdb36 275 SUPERFAMILY SSF51120 164 266 6.02E-15 T 29-03-2018 IPR011049 Serralysin-like metalloprotease, C-terminal SMALA_RS41740 ae0f28f5f4a803e754880f4636ffdb36 275 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 227 245 - T 29-03-2018 IPR018511 Hemolysin-type calcium-binding conserved site SMALA_RS41740 ae0f28f5f4a803e754880f4636ffdb36 275 Gene3D G3DSA:2.150.10.10 191 272 2.0E-13 T 29-03-2018 SMALA_RS41740 ae0f28f5f4a803e754880f4636ffdb36 275 Gene3D G3DSA:2.150.10.10 19 190 3.2E-7 T 29-03-2018 SMALA_RS36615 56f031a478b50f78e520c4e1a6ee81e1 311 Gene3D G3DSA:3.40.1790.10 2 306 7.1E-137 T 29-03-2018 IPR007342 Pseudouridine-5'-phosphate glycosidase GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 SMALA_RS36615 56f031a478b50f78e520c4e1a6ee81e1 311 Pfam PF04227 Indigoidine synthase A like protein 13 301 3.1E-130 T 29-03-2018 IPR007342 Pseudouridine-5'-phosphate glycosidase GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 SMALA_RS36615 56f031a478b50f78e520c4e1a6ee81e1 311 SUPERFAMILY SSF110581 7 303 7.85E-115 T 29-03-2018 SMALA_RS36615 56f031a478b50f78e520c4e1a6ee81e1 311 Hamap MF_01876 Pseudouridine-5'-phosphate glycosidase [psuG]. 12 305 43.491 T 29-03-2018 IPR007342 Pseudouridine-5'-phosphate glycosidase GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 SMALA_RS12715 f8bd9c878b81409d443f3fbf3bb33c7c 290 Pfam PF00950 ABC 3 transport family 7 261 5.7E-66 T 29-03-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 SMALA_RS12715 f8bd9c878b81409d443f3fbf3bb33c7c 290 Gene3D G3DSA:1.10.3470.10 3 274 2.8E-27 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SMALA_RS12715 f8bd9c878b81409d443f3fbf3bb33c7c 290 SUPERFAMILY SSF81345 4 259 1.83E-34 T 29-03-2018 IPR029022 ABC transporter, BtuC-like SMALA_RS10415 7699db00011e44864e728b3a6ced036e 414 Gene3D G3DSA:3.30.565.10 275 408 8.5E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS10415 7699db00011e44864e728b3a6ced036e 414 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 311 400 4.4E-9 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS10415 7699db00011e44864e728b3a6ced036e 414 SUPERFAMILY SSF55874 281 400 5.63E-14 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS10415 7699db00011e44864e728b3a6ced036e 414 Pfam PF07730 Histidine kinase 181 218 6.4E-6 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMALA_RS17180 2cfe04f7d8f1267ba74de820a9e2eaae 251 Gene3D G3DSA:3.40.50.10490 2 246 3.7E-47 T 29-03-2018 SMALA_RS17180 2cfe04f7d8f1267ba74de820a9e2eaae 251 Pfam PF13580 SIS domain 9 146 4.8E-41 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 SMALA_RS17180 2cfe04f7d8f1267ba74de820a9e2eaae 251 SUPERFAMILY SSF53697 9 204 3.84E-24 T 29-03-2018 SMALA_RS17180 2cfe04f7d8f1267ba74de820a9e2eaae 251 Hamap MF_01240 UPF0309 protein . 6 250 38.309 T 29-03-2018 IPR022951 Uncharacterised protein family UPF0309 SMALA_RS21905 eab5de33b8af50be8453b1200ffa29bb 78 Gene3D G3DSA:3.30.70.20 1 63 1.4E-7 T 29-03-2018 SMALA_RS21905 eab5de33b8af50be8453b1200ffa29bb 78 SUPERFAMILY SSF54862 2 60 4.51E-12 T 29-03-2018 SMALA_RS21905 eab5de33b8af50be8453b1200ffa29bb 78 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 5 60 7.8E-12 T 29-03-2018 SMALA_RS11985 ae1bbead25cd96fa470a714c9b6c2af4 195 Gene3D G3DSA:3.90.1570.10 2 194 2.0E-28 T 29-03-2018 SMALA_RS11985 ae1bbead25cd96fa470a714c9b6c2af4 195 Pfam PF05685 Putative restriction endonuclease 13 181 3.3E-21 T 29-03-2018 IPR008538 Domain of unknown function DUF820 SMALA_RS11985 ae1bbead25cd96fa470a714c9b6c2af4 195 SUPERFAMILY SSF52980 4 160 5.9E-16 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 SMALA_RS31165 b54fa90471ba44eb47a75fe6628efd16 260 SMART SM00382 34 223 2.1E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS31165 b54fa90471ba44eb47a75fe6628efd16 260 Pfam PF00005 ABC transporter 25 175 9.4E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS31165 b54fa90471ba44eb47a75fe6628efd16 260 SUPERFAMILY SSF52540 8 226 2.24E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS31165 b54fa90471ba44eb47a75fe6628efd16 260 Gene3D G3DSA:3.40.50.300 6 243 7.5E-53 T 29-03-2018 SMALA_RS34175 237276f6e29b138c3f4b4584dbea2673 204 SUPERFAMILY SSF63817 54 199 2.59E-13 T 29-03-2018 IPR023365 Sortase domain SMALA_RS34175 237276f6e29b138c3f4b4584dbea2673 204 Gene3D G3DSA:2.40.260.10 15 204 4.5E-25 T 29-03-2018 IPR023365 Sortase domain SMALA_RS34175 237276f6e29b138c3f4b4584dbea2673 204 Pfam PF04203 Sortase family 61 199 1.8E-16 T 29-03-2018 IPR005754 Sortase family SMALA_RS39300 e266cc3c740d8e0558ede0a25758db25 141 Pfam PF12802 MarR family 31 87 5.9E-12 T 29-03-2018 SMALA_RS39300 e266cc3c740d8e0558ede0a25758db25 141 SMART SM00347 25 123 0.001 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS39300 e266cc3c740d8e0558ede0a25758db25 141 Gene3D G3DSA:1.10.10.10 1 136 1.6E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS39300 e266cc3c740d8e0558ede0a25758db25 141 SUPERFAMILY SSF46785 4 134 3.28E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS40395 13639b34040ceceba5c5ddb8b2c476ec 301 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 129 287 3.1E-16 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS40395 13639b34040ceceba5c5ddb8b2c476ec 301 SUPERFAMILY SSF161098 28 301 1.5E-62 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS40395 13639b34040ceceba5c5ddb8b2c476ec 301 Gene3D G3DSA:1.10.3720.10 22 289 5.1E-37 T 29-03-2018 SMALA_RS27965 755388ee4b0cdd765228b511d17c9268 77 Gene3D G3DSA:3.30.70.920 1 77 3.1E-16 T 29-03-2018 SMALA_RS27965 755388ee4b0cdd765228b511d17c9268 77 Pfam PF01037 Lrp/AsnC ligand binding domain 6 75 1.7E-12 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain SMALA_RS27965 755388ee4b0cdd765228b511d17c9268 77 SUPERFAMILY SSF54909 2 75 7.78E-15 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel SMALA_RS03680 24a5a73326703e4916b0524db4ea665a 319 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 200 225 2.1E-7 T 29-03-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal SMALA_RS03680 24a5a73326703e4916b0524db4ea665a 319 SUPERFAMILY SSF50249 171 295 6.34E-30 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMALA_RS03680 24a5a73326703e4916b0524db4ea665a 319 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 69 132 2.2E-11 T 29-03-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal SMALA_RS03680 24a5a73326703e4916b0524db4ea665a 319 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 229 292 1.3E-12 T 29-03-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal SMALA_RS03680 24a5a73326703e4916b0524db4ea665a 319 Gene3D G3DSA:2.40.50.140 72 139 2.2E-17 T 29-03-2018 SMALA_RS03680 24a5a73326703e4916b0524db4ea665a 319 Gene3D G3DSA:2.40.50.140 226 299 2.1E-15 T 29-03-2018 SMALA_RS03680 24a5a73326703e4916b0524db4ea665a 319 SUPERFAMILY SSF50249 9 140 1.88E-25 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMALA_RS03755 34863104577bdb949370b729075dab40 702 Gene3D G3DSA:2.30.110.10 546 686 9.3E-18 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS03755 34863104577bdb949370b729075dab40 702 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 566 640 5.6E-7 T 29-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 SMALA_RS03755 34863104577bdb949370b729075dab40 702 SUPERFAMILY SSF50475 555 668 1.37E-20 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS27250 435ae7c3829de6ce0e4f505690137d72 79 Pfam PF04149 Domain of unknown function (DUF397) 6 53 7.5E-19 T 29-03-2018 IPR007278 Domain of unknown function DUF397 SMALA_RS25335 338bafcfc9a4ac0927bd6767486b4b97 225 Pfam PF11361 Protein of unknown function (DUF3159) 29 212 7.8E-59 T 29-03-2018 IPR016566 Uncharacterised conserved protein UCP010219 SMALA_RS25335 338bafcfc9a4ac0927bd6767486b4b97 225 PIRSF PIRSF010219 2 223 2.1E-61 T 29-03-2018 IPR016566 Uncharacterised conserved protein UCP010219 SMALA_RS14215 17c56e9f51ff816f1087ca32aee6fc89 548 Gene3D G3DSA:3.30.379.10 46 183 3.3E-31 T 29-03-2018 SMALA_RS14215 17c56e9f51ff816f1087ca32aee6fc89 548 SUPERFAMILY SSF51445 195 539 1.24E-109 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS14215 17c56e9f51ff816f1087ca32aee6fc89 548 SUPERFAMILY SSF55545 47 194 4.71E-31 T 29-03-2018 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMALA_RS14215 17c56e9f51ff816f1087ca32aee6fc89 548 Gene3D G3DSA:3.20.20.80 184 543 6.5E-121 T 29-03-2018 SMALA_RS14215 17c56e9f51ff816f1087ca32aee6fc89 548 Pfam PF02838 Glycosyl hydrolase family 20, domain 2 54 191 1.7E-22 T 29-03-2018 IPR015882 Beta-hexosaminidase, bacteial type, N-terminal KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822 SMALA_RS14215 17c56e9f51ff816f1087ca32aee6fc89 548 PRINTS PR00738 Glycosyl hydrolase family 20 signature 474 490 1.6E-49 T 29-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMALA_RS14215 17c56e9f51ff816f1087ca32aee6fc89 548 PRINTS PR00738 Glycosyl hydrolase family 20 signature 492 509 1.6E-49 T 29-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMALA_RS14215 17c56e9f51ff816f1087ca32aee6fc89 548 PRINTS PR00738 Glycosyl hydrolase family 20 signature 325 343 1.6E-49 T 29-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMALA_RS14215 17c56e9f51ff816f1087ca32aee6fc89 548 PRINTS PR00738 Glycosyl hydrolase family 20 signature 189 206 1.6E-49 T 29-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMALA_RS14215 17c56e9f51ff816f1087ca32aee6fc89 548 PRINTS PR00738 Glycosyl hydrolase family 20 signature 277 294 1.6E-49 T 29-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMALA_RS14215 17c56e9f51ff816f1087ca32aee6fc89 548 PRINTS PR00738 Glycosyl hydrolase family 20 signature 218 239 1.6E-49 T 29-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMALA_RS14215 17c56e9f51ff816f1087ca32aee6fc89 548 PRINTS PR00738 Glycosyl hydrolase family 20 signature 347 360 1.6E-49 T 29-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMALA_RS14215 17c56e9f51ff816f1087ca32aee6fc89 548 PRINTS PR00738 Glycosyl hydrolase family 20 signature 147 167 1.6E-49 T 29-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMALA_RS14215 17c56e9f51ff816f1087ca32aee6fc89 548 Pfam PF00728 Glycosyl hydrolase family 20, catalytic domain 368 509 3.5E-25 T 29-03-2018 IPR015883 Glycoside hydrolase family 20, catalytic domain GO:0004553|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822 SMALA_RS14215 17c56e9f51ff816f1087ca32aee6fc89 548 Pfam PF00728 Glycosyl hydrolase family 20, catalytic domain 195 364 4.7E-60 T 29-03-2018 IPR015883 Glycoside hydrolase family 20, catalytic domain GO:0004553|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822 SMALA_RS17770 00fe5ef7dcb5a8fa0d47f469a30707b2 181 Gene3D G3DSA:3.40.1440.10 15 158 1.4E-7 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily SMALA_RS21630 46fbb7857694529e767a336fe60afb1c 153 SUPERFAMILY SSF54593 1 141 2.01E-25 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS21630 46fbb7857694529e767a336fe60afb1c 153 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 134 1.7E-12 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMALA_RS21630 46fbb7857694529e767a336fe60afb1c 153 Gene3D G3DSA:3.10.180.10 1 152 2.0E-26 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS17690 a185a509893968f1211eecf293ecfa90 235 SUPERFAMILY SSF110087 41 160 6.28E-5 T 29-03-2018 IPR007410 Copper chaperone PCuAC SMALA_RS11545 02ed8069f21d194639cf08b97ea64c4c 187 Pfam PF02441 Flavoprotein 17 150 8.0E-10 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 SMALA_RS11545 02ed8069f21d194639cf08b97ea64c4c 187 SUPERFAMILY SSF52507 8 154 3.53E-18 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 SMALA_RS11545 02ed8069f21d194639cf08b97ea64c4c 187 Gene3D G3DSA:3.40.50.1950 1 165 9.2E-19 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 SMALA_RS19980 5d71be9fd4ea6a0faf44fb246713f29e 475 SUPERFAMILY SSF51230 4 92 5.5E-24 T 29-03-2018 IPR011053 Single hybrid motif SMALA_RS19980 5d71be9fd4ea6a0faf44fb246713f29e 475 SUPERFAMILY SSF52777 236 472 1.51E-71 T 29-03-2018 SMALA_RS19980 5d71be9fd4ea6a0faf44fb246713f29e 475 Pfam PF02817 e3 binding domain 175 209 4.2E-13 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 SMALA_RS19980 5d71be9fd4ea6a0faf44fb246713f29e 475 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 247 472 1.0E-70 T 29-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 SMALA_RS19980 5d71be9fd4ea6a0faf44fb246713f29e 475 Gene3D G3DSA:3.90.1170.30 48 171 0.12 T 29-03-2018 SMALA_RS19980 5d71be9fd4ea6a0faf44fb246713f29e 475 Gene3D G3DSA:3.90.1170.30 2 47 2.1E-12 T 29-03-2018 SMALA_RS19980 5d71be9fd4ea6a0faf44fb246713f29e 475 Gene3D G3DSA:3.30.559.10 231 475 8.1E-80 T 29-03-2018 SMALA_RS19980 5d71be9fd4ea6a0faf44fb246713f29e 475 Pfam PF00364 Biotin-requiring enzyme 6 77 3.0E-16 T 29-03-2018 IPR000089 Biotin/lipoyl attachment SMALA_RS19980 5d71be9fd4ea6a0faf44fb246713f29e 475 SUPERFAMILY SSF47005 169 212 5.89E-11 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 SMALA_RS19980 5d71be9fd4ea6a0faf44fb246713f29e 475 Gene3D G3DSA:4.10.320.10 172 221 2.0E-16 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 SMALA_RS25530 f82d92e83b34a0a473061b003117abed 144 SUPERFAMILY SSF55811 3 129 2.17E-31 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMALA_RS25530 f82d92e83b34a0a473061b003117abed 144 PRINTS PR00502 NUDIX hydrolase family signature 32 46 3.8E-8 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMALA_RS25530 f82d92e83b34a0a473061b003117abed 144 PRINTS PR00502 NUDIX hydrolase family signature 46 61 3.8E-8 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMALA_RS25530 f82d92e83b34a0a473061b003117abed 144 Gene3D G3DSA:3.90.79.10 1 134 2.8E-30 T 29-03-2018 SMALA_RS25530 f82d92e83b34a0a473061b003117abed 144 Pfam PF00293 NUDIX domain 4 113 2.0E-19 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SMALA_RS25530 f82d92e83b34a0a473061b003117abed 144 ProSitePatterns PS00893 Nudix box signature. 37 58 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 SMALA_RS37345 1e45e39e750d1104f8156e62179337a5 407 Pfam PF00144 Beta-lactamase 66 362 2.6E-59 T 29-03-2018 IPR001466 Beta-lactamase-related SMALA_RS37345 1e45e39e750d1104f8156e62179337a5 407 Gene3D G3DSA:3.40.710.10 35 388 1.2E-72 T 29-03-2018 SMALA_RS37345 1e45e39e750d1104f8156e62179337a5 407 SUPERFAMILY SSF56601 66 376 1.72E-74 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMALA_RS20950 dd620652a01cd0c91d703fb869b3f5b0 68 Pfam PF12728 Helix-turn-helix domain 11 59 3.1E-11 T 29-03-2018 SMALA_RS20950 dd620652a01cd0c91d703fb869b3f5b0 68 Gene3D G3DSA:1.10.1660.10 1 68 1.2E-12 T 29-03-2018 SMALA_RS20950 dd620652a01cd0c91d703fb869b3f5b0 68 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 11 58 6.9E-9 T 29-03-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 SMALA_RS20950 dd620652a01cd0c91d703fb869b3f5b0 68 SUPERFAMILY SSF46955 11 59 3.98E-11 T 29-03-2018 IPR009061 Putative DNA-binding domain SMALA_RS16235 446d866ec3bdca322bb60e37cf558b37 133 SMART SM00960 6 97 1.2E-20 T 29-03-2018 IPR004942 Roadblock/LAMTOR2 domain SMALA_RS16235 446d866ec3bdca322bb60e37cf558b37 133 SUPERFAMILY SSF103196 3 126 1.48E-25 T 29-03-2018 SMALA_RS16235 446d866ec3bdca322bb60e37cf558b37 133 Gene3D G3DSA:3.30.450.30 1 129 4.2E-39 T 29-03-2018 SMALA_RS16235 446d866ec3bdca322bb60e37cf558b37 133 Pfam PF03259 Roadblock/LC7 domain 9 96 6.4E-23 T 29-03-2018 IPR004942 Roadblock/LAMTOR2 domain SMALA_RS09745 2973d40a6feca438812ba1e7e2fb9223 302 Gene3D G3DSA:3.40.50.150 23 261 2.5E-28 T 29-03-2018 SMALA_RS09745 2973d40a6feca438812ba1e7e2fb9223 302 SUPERFAMILY SSF53335 33 301 3.71E-31 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS09745 2973d40a6feca438812ba1e7e2fb9223 302 Pfam PF08241 Methyltransferase domain 83 201 1.6E-17 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 SMALA_RS30600 e0a726778bfd482192615a4eac6ade9f 322 Pfam PF00294 pfkB family carbohydrate kinase 8 302 3.8E-42 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB SMALA_RS30600 e0a726778bfd482192615a4eac6ade9f 322 Gene3D G3DSA:3.40.1190.20 2 312 2.8E-58 T 29-03-2018 IPR029056 Ribokinase-like SMALA_RS30600 e0a726778bfd482192615a4eac6ade9f 322 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 254 267 - T 29-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 SMALA_RS30600 e0a726778bfd482192615a4eac6ade9f 322 SUPERFAMILY SSF53613 6 303 6.39E-65 T 29-03-2018 IPR029056 Ribokinase-like SMALA_RS32090 53b1a4e1af6eefc2ba48f3814fecb02d 287 TIGRFAM TIGR03464 HpnC: squalene synthase HpnC 3 282 4.0E-98 T 29-03-2018 IPR017827 Squalene synthase HpnC SMALA_RS32090 53b1a4e1af6eefc2ba48f3814fecb02d 287 Pfam PF00494 Squalene/phytoene synthase 4 273 3.0E-68 T 29-03-2018 IPR002060 Squalene/phytoene synthase GO:0009058|GO:0016740 SMALA_RS32090 53b1a4e1af6eefc2ba48f3814fecb02d 287 Gene3D G3DSA:1.10.600.10 2 287 4.9E-74 T 29-03-2018 IPR008949 Isoprenoid synthase domain SMALA_RS32090 53b1a4e1af6eefc2ba48f3814fecb02d 287 SUPERFAMILY SSF48576 6 285 1.44E-57 T 29-03-2018 IPR008949 Isoprenoid synthase domain SMALA_RS32120 d88f8142a6ed964e6412b05a16be3db8 341 SUPERFAMILY SSF102114 23 309 1.96E-49 T 29-03-2018 SMALA_RS32120 d88f8142a6ed964e6412b05a16be3db8 341 TIGRFAM TIGR03470 HpnH: hopanoid biosynthesis associated radical SAM protein HpnH 1 319 1.7E-160 T 29-03-2018 IPR017833 Hopanoid biosynthesis associated radical SAM protein HpnH SMALA_RS32120 d88f8142a6ed964e6412b05a16be3db8 341 Pfam PF11946 Domain of unknown function (DUF3463) 197 329 2.3E-56 T 29-03-2018 IPR022563 Domain of unknown function DUF3463 SMALA_RS32120 d88f8142a6ed964e6412b05a16be3db8 341 Gene3D G3DSA:3.20.20.70 16 339 3.2E-30 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS32120 d88f8142a6ed964e6412b05a16be3db8 341 Pfam PF04055 Radical SAM superfamily 35 188 2.0E-16 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 SMALA_RS34820 bef6c4201243da7de70fea9ee939d30d 298 Hamap MF_01384 Urease accessory protein UreD [ureD]. 53 298 19.576 T 29-03-2018 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 SMALA_RS34820 bef6c4201243da7de70fea9ee939d30d 298 Pfam PF01774 UreD urease accessory protein 96 249 3.7E-28 T 29-03-2018 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 SMALA_RS40700 5c4e7ed2d4cb44bdfffec40dc3a37ca0 303 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 140 251 1.3E-18 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMALA_RS40700 5c4e7ed2d4cb44bdfffec40dc3a37ca0 303 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 15 97 2.1E-6 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMALA_RS40700 5c4e7ed2d4cb44bdfffec40dc3a37ca0 303 SUPERFAMILY SSF54593 6 253 7.68E-37 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS40700 5c4e7ed2d4cb44bdfffec40dc3a37ca0 303 Gene3D G3DSA:3.10.180.10 6 123 2.4E-11 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS40700 5c4e7ed2d4cb44bdfffec40dc3a37ca0 303 Gene3D G3DSA:3.10.180.10 132 285 3.6E-30 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS19820 d54924e9adcca55ccdd41d1aedc34132 225 Gene3D G3DSA:2.40.260.10 38 223 5.3E-37 T 29-03-2018 IPR023365 Sortase domain SMALA_RS19820 d54924e9adcca55ccdd41d1aedc34132 225 Pfam PF04203 Sortase family 78 209 3.0E-26 T 29-03-2018 IPR005754 Sortase family SMALA_RS19820 d54924e9adcca55ccdd41d1aedc34132 225 SUPERFAMILY SSF63817 66 212 2.09E-29 T 29-03-2018 IPR023365 Sortase domain SMALA_RS19820 d54924e9adcca55ccdd41d1aedc34132 225 TIGRFAM TIGR01076 sortase_fam: sortase 80 208 8.0E-14 T 29-03-2018 IPR005754 Sortase family SMALA_RS34875 172256d610919dd0ca8252d6ff5f1a49 412 SUPERFAMILY SSF53623 226 279 7.2E-30 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMALA_RS34875 172256d610919dd0ca8252d6ff5f1a49 412 SUPERFAMILY SSF53623 51 196 7.2E-30 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMALA_RS34875 172256d610919dd0ca8252d6ff5f1a49 412 Pfam PF08353 Domain of unknown function (DUF1727) 304 403 1.9E-21 T 29-03-2018 IPR013564 Domain of unknown function DUF1727 SMALA_RS34875 172256d610919dd0ca8252d6ff5f1a49 412 Pfam PF08245 Mur ligase middle domain 65 266 5.7E-12 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMALA_RS34875 172256d610919dd0ca8252d6ff5f1a49 412 Gene3D G3DSA:3.40.1190.10 40 282 3.5E-35 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMALA_RS35785 255bfa39e49aa7a5570f4514334bfcc0 155 Gene3D G3DSA:3.30.565.10 22 153 6.5E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS35785 255bfa39e49aa7a5570f4514334bfcc0 155 Pfam PF13581 Histidine kinase-like ATPase domain 32 146 5.6E-12 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS35785 255bfa39e49aa7a5570f4514334bfcc0 155 SUPERFAMILY SSF55874 51 148 3.18E-10 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS14035 a278c6aa40ba3dcef5a4bfce06f46004 318 Pfam PF14100 Methane oxygenase PmoA 15 312 1.7E-78 T 29-03-2018 IPR029475 Methane oxygenase PmoA SMALA_RS39020 27e9f15334211f2e2ac1dd3373e2e23f 286 Gene3D G3DSA:3.40.50.300 11 284 4.6E-76 T 29-03-2018 SMALA_RS39020 27e9f15334211f2e2ac1dd3373e2e23f 286 SUPERFAMILY SSF52540 14 263 9.13E-73 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS39020 27e9f15334211f2e2ac1dd3373e2e23f 286 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 243 275 6.9E-7 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMALA_RS39020 27e9f15334211f2e2ac1dd3373e2e23f 286 Pfam PF00005 ABC transporter 36 192 2.6E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS39020 27e9f15334211f2e2ac1dd3373e2e23f 286 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS39020 27e9f15334211f2e2ac1dd3373e2e23f 286 SMART SM00382 44 241 1.5E-18 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS13165 a77e3d4a694d2d14f449bfa8e9c7d49d 236 Pfam PF04093 rod shape-determining protein MreD 4 127 1.6E-6 T 29-03-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 SMALA_RS13165 a77e3d4a694d2d14f449bfa8e9c7d49d 236 TIGRFAM TIGR03426 shape_MreD: rod shape-determining protein MreD 5 158 2.1E-18 T 29-03-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 SMALA_RS08100 f45efed0459bd6e1ef90617d02bed9c2 114 Pfam PF02656 Domain of unknown function (DUF202) 11 76 4.1E-15 T 29-03-2018 IPR003807 Domain of unknown function DUF202 SMALA_RS22250 22e8b4bab8c27a9e32438d71eb8c9480 223 Gene3D G3DSA:1.10.10.10 141 223 1.5E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS22250 22e8b4bab8c27a9e32438d71eb8c9480 223 SMART SM00448 5 129 8.6E-11 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS22250 22e8b4bab8c27a9e32438d71eb8c9480 223 Pfam PF00196 Bacterial regulatory proteins, luxR family 160 204 2.3E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS22250 22e8b4bab8c27a9e32438d71eb8c9480 223 Gene3D G3DSA:3.40.50.2300 4 140 3.5E-20 T 29-03-2018 SMALA_RS22250 22e8b4bab8c27a9e32438d71eb8c9480 223 Pfam PF00072 Response regulator receiver domain 7 118 3.4E-14 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS22250 22e8b4bab8c27a9e32438d71eb8c9480 223 SMART SM00421 157 219 9.5E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS22250 22e8b4bab8c27a9e32438d71eb8c9480 223 SUPERFAMILY SSF52172 4 177 5.47E-16 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS22250 22e8b4bab8c27a9e32438d71eb8c9480 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 174 190 4.0E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS22250 22e8b4bab8c27a9e32438d71eb8c9480 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 160 174 4.0E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS22250 22e8b4bab8c27a9e32438d71eb8c9480 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 190 202 4.0E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS28490 b88121cf62b4d0a19dcdb3f0ed5d650d 317 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 12 316 16.987 T 29-03-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 SMALA_RS28490 b88121cf62b4d0a19dcdb3f0ed5d650d 317 Gene3D G3DSA:3.30.2350.10 11 239 1.5E-77 T 29-03-2018 SMALA_RS28490 b88121cf62b4d0a19dcdb3f0ed5d650d 317 SUPERFAMILY SSF55120 13 237 5.76E-68 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 SMALA_RS28490 b88121cf62b4d0a19dcdb3f0ed5d650d 317 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 13 230 4.4E-66 T 29-03-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 SMALA_RS28490 b88121cf62b4d0a19dcdb3f0ed5d650d 317 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 34 191 6.8E-47 T 29-03-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 SMALA_RS28490 b88121cf62b4d0a19dcdb3f0ed5d650d 317 Pfam PF09142 tRNA Pseudouridine synthase II, C terminal 247 316 7.2E-15 T 29-03-2018 IPR015225 tRNA pseudouridine synthase II, TruB, subfamily 2, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 SMALA_RS28490 b88121cf62b4d0a19dcdb3f0ed5d650d 317 Gene3D G3DSA:2.30.130.10 240 316 8.8E-17 T 29-03-2018 IPR002478 PUA domain GO:0003723 SMALA_RS28490 b88121cf62b4d0a19dcdb3f0ed5d650d 317 SUPERFAMILY SSF88697 247 316 3.53E-7 T 29-03-2018 IPR015947 PUA-like domain SMALA_RS28490 b88121cf62b4d0a19dcdb3f0ed5d650d 317 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 192 235 6.8E-12 T 29-03-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 SMALA_RS36920 d3f1437179f3bcae7c67ecbf6e3d065d 245 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 79 102 5.5E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS36920 d3f1437179f3bcae7c67ecbf6e3d065d 245 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 58 71 5.5E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS36920 d3f1437179f3bcae7c67ecbf6e3d065d 245 SUPERFAMILY SSF46689 45 118 4.62E-19 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS36920 d3f1437179f3bcae7c67ecbf6e3d065d 245 ProSitePatterns PS01081 TetR-type HTH domain signature. 70 101 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site SMALA_RS36920 d3f1437179f3bcae7c67ecbf6e3d065d 245 Pfam PF00440 Bacterial regulatory proteins, tetR family 60 103 1.5E-16 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS36920 d3f1437179f3bcae7c67ecbf6e3d065d 245 Gene3D G3DSA:1.10.260.40 80 162 6.1E-13 T 29-03-2018 SMALA_RS36920 d3f1437179f3bcae7c67ecbf6e3d065d 245 Gene3D G3DSA:1.10.10.60 23 79 6.7E-17 T 29-03-2018 SMALA_RS40040 473d282afbb2c77518f790a716eaeae8 323 Gene3D G3DSA:3.90.1150.10 251 323 0.012 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS40040 473d282afbb2c77518f790a716eaeae8 323 SMART SM00797 27 307 1.6E-55 T 29-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B SMALA_RS40040 473d282afbb2c77518f790a716eaeae8 323 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 29 290 1.0E-60 T 29-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B SMALA_RS28965 9a223adcc7a3ebac9c321062df996272 173 Pfam PF03477 ATP cone domain 47 132 9.1E-14 T 29-03-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 SMALA_RS28965 9a223adcc7a3ebac9c321062df996272 173 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 150 76.642 T 29-03-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 SMALA_RS28965 9a223adcc7a3ebac9c321062df996272 173 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 144 2.2E-46 T 29-03-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 SMALA_RS42535 1094316afbb5673d5b11b223d89f4b5f 340 PRINTS PR00069 Aldo-keto reductase signature 137 154 4.3E-6 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMALA_RS42535 1094316afbb5673d5b11b223d89f4b5f 340 PRINTS PR00069 Aldo-keto reductase signature 42 66 4.3E-6 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMALA_RS42535 1094316afbb5673d5b11b223d89f4b5f 340 PRINTS PR00069 Aldo-keto reductase signature 106 124 4.3E-6 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMALA_RS42535 1094316afbb5673d5b11b223d89f4b5f 340 Pfam PF00248 Aldo/keto reductase family 18 315 6.7E-73 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS42535 1094316afbb5673d5b11b223d89f4b5f 340 Gene3D G3DSA:3.20.20.100 6 317 3.8E-89 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS42535 1094316afbb5673d5b11b223d89f4b5f 340 SUPERFAMILY SSF51430 6 315 4.98E-93 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS16200 6c5a7d1a1baa512d00683770461016a1 182 Pfam PF04417 Protein of unknown function (DUF501) 36 156 5.2E-36 T 29-03-2018 IPR007511 Protein of unknown function DUF501 SMALA_RS18860 e994d11366d4062a3e0fd4e05bf02649 203 Pfam PF10935 Protein of unknown function (DUF2637) 6 118 3.8E-21 T 29-03-2018 IPR021235 Protein of unknown function DUF2637 SMALA_RS31415 b1e82063aae38c6f0689851468aa0c48 350 SUPERFAMILY SSF51658 68 344 2.07E-34 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SMALA_RS31415 b1e82063aae38c6f0689851468aa0c48 350 Gene3D G3DSA:3.20.20.150 62 345 3.2E-40 T 29-03-2018 SMALA_RS31415 b1e82063aae38c6f0689851468aa0c48 350 Pfam PF01261 Xylose isomerase-like TIM barrel 86 299 7.6E-24 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SMALA_RS12510 33e81bcd2fdb8fa716976fd02f70587a 267 TIGRFAM TIGR03704 PrmC_rel_meth: putative protein-(glutamine-N5) methyltransferase, unknown substrate-specific 13 260 3.7E-125 T 29-03-2018 IPR022446 Conserved hypothetical protein CHP03704, protein-(glutamine-N5) methyltransferase SMALA_RS12510 33e81bcd2fdb8fa716976fd02f70587a 267 Gene3D G3DSA:3.40.50.150 68 257 9.4E-38 T 29-03-2018 SMALA_RS12510 33e81bcd2fdb8fa716976fd02f70587a 267 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 42 233 3.2E-39 T 29-03-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 SMALA_RS12510 33e81bcd2fdb8fa716976fd02f70587a 267 Pfam PF05175 Methyltransferase small domain 72 195 8.0E-13 T 29-03-2018 IPR007848 Methyltransferase small domain GO:0008168 SMALA_RS12510 33e81bcd2fdb8fa716976fd02f70587a 267 Gene3D G3DSA:1.10.8.10 34 67 1.4E-7 T 29-03-2018 SMALA_RS12510 33e81bcd2fdb8fa716976fd02f70587a 267 SUPERFAMILY SSF53335 49 226 7.63E-45 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS21505 23564bec01ec53ed8b5b546b8669bec9 88 Gene3D G3DSA:3.10.20.30 6 88 1.4E-17 T 29-03-2018 IPR012675 Beta-grasp domain SMALA_RS21505 23564bec01ec53ed8b5b546b8669bec9 88 SUPERFAMILY SSF54285 7 88 2.45E-12 T 29-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp SMALA_RS21505 23564bec01ec53ed8b5b546b8669bec9 88 Pfam PF02597 ThiS family 8 88 1.4E-8 T 29-03-2018 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 SMALA_RS10295 082a3289e6bf667b4683b8d753ae2200 330 Pfam PF00005 ABC transporter 82 237 1.2E-8 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS10295 082a3289e6bf667b4683b8d753ae2200 330 Gene3D G3DSA:3.40.50.300 31 271 8.9E-26 T 29-03-2018 SMALA_RS10295 082a3289e6bf667b4683b8d753ae2200 330 SUPERFAMILY SSF52540 63 270 2.53E-21 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS10030 e4e026bac47e891892724b1f99077d3e 326 Gene3D G3DSA:3.40.50.1980 24 156 9.2E-26 T 29-03-2018 SMALA_RS10030 e4e026bac47e891892724b1f99077d3e 326 Gene3D G3DSA:3.40.50.1980 157 326 3.9E-22 T 29-03-2018 SMALA_RS10030 e4e026bac47e891892724b1f99077d3e 326 SUPERFAMILY SSF53807 39 320 1.18E-48 T 29-03-2018 SMALA_RS10030 e4e026bac47e891892724b1f99077d3e 326 Pfam PF01497 Periplasmic binding protein 57 301 5.8E-17 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 SMALA_RS39730 9401f2bbb910bcd9b93d212f621a02ce 388 Gene3D G3DSA:3.90.1300.10 2 91 1.3E-13 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMALA_RS39730 9401f2bbb910bcd9b93d212f621a02ce 388 Gene3D G3DSA:3.90.1300.10 92 273 3.4E-41 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMALA_RS39730 9401f2bbb910bcd9b93d212f621a02ce 388 SUPERFAMILY SSF75304 3 383 5.36E-80 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMALA_RS39730 9401f2bbb910bcd9b93d212f621a02ce 388 Gene3D G3DSA:3.90.1300.10 274 386 4.4E-22 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMALA_RS39730 9401f2bbb910bcd9b93d212f621a02ce 388 Pfam PF01425 Amidase 31 84 7.2E-5 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMALA_RS39730 9401f2bbb910bcd9b93d212f621a02ce 388 Pfam PF01425 Amidase 291 378 8.5E-12 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMALA_RS39730 9401f2bbb910bcd9b93d212f621a02ce 388 Pfam PF01425 Amidase 92 231 5.8E-35 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMALA_RS12710 fadc75e112e1754ed5c8929a14384e3d 250 Pfam PF00005 ABC transporter 16 163 1.1E-24 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS12710 fadc75e112e1754ed5c8929a14384e3d 250 SMART SM00382 25 219 7.4E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS12710 fadc75e112e1754ed5c8929a14384e3d 250 Gene3D G3DSA:3.40.50.300 1 242 1.9E-52 T 29-03-2018 SMALA_RS12710 fadc75e112e1754ed5c8929a14384e3d 250 SUPERFAMILY SSF52540 1 224 5.98E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS11065 7cbd79075b344ec5ee42486ac28c9480 285 Pfam PF00557 Metallopeptidase family M24 48 276 2.9E-53 T 29-03-2018 IPR000994 Peptidase M24 SMALA_RS11065 7cbd79075b344ec5ee42486ac28c9480 285 Gene3D G3DSA:3.90.230.10 39 285 7.8E-88 T 29-03-2018 SMALA_RS11065 7cbd79075b344ec5ee42486ac28c9480 285 Hamap MF_01974 Methionine aminopeptidase [map]. 39 285 40.054 T 29-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 SMALA_RS11065 7cbd79075b344ec5ee42486ac28c9480 285 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 202 220 - T 29-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 SMALA_RS11065 7cbd79075b344ec5ee42486ac28c9480 285 SUPERFAMILY SSF55920 7 284 3.66E-86 T 29-03-2018 IPR000994 Peptidase M24 SMALA_RS11065 7cbd79075b344ec5ee42486ac28c9480 285 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 41 283 4.7E-92 T 29-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 SMALA_RS11065 7cbd79075b344ec5ee42486ac28c9480 285 PRINTS PR00599 Methionine aminopeptidase-1 signature 104 117 1.1E-20 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 SMALA_RS11065 7cbd79075b344ec5ee42486ac28c9480 285 PRINTS PR00599 Methionine aminopeptidase-1 signature 126 142 1.1E-20 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 SMALA_RS11065 7cbd79075b344ec5ee42486ac28c9480 285 PRINTS PR00599 Methionine aminopeptidase-1 signature 227 239 1.1E-20 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 SMALA_RS11065 7cbd79075b344ec5ee42486ac28c9480 285 PRINTS PR00599 Methionine aminopeptidase-1 signature 196 208 1.1E-20 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 SMALA_RS36090 b1ed31e23e9c7b8a7345a571b62e5342 430 PRINTS PR00359 B-class P450 signature 348 363 1.7E-36 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS36090 b1ed31e23e9c7b8a7345a571b62e5342 430 PRINTS PR00359 B-class P450 signature 320 347 1.7E-36 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS36090 b1ed31e23e9c7b8a7345a571b62e5342 430 PRINTS PR00359 B-class P450 signature 378 389 1.7E-36 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS36090 b1ed31e23e9c7b8a7345a571b62e5342 430 PRINTS PR00359 B-class P450 signature 369 378 1.7E-36 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS36090 b1ed31e23e9c7b8a7345a571b62e5342 430 PRINTS PR00359 B-class P450 signature 94 105 1.7E-36 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS36090 b1ed31e23e9c7b8a7345a571b62e5342 430 PRINTS PR00359 B-class P450 signature 303 314 1.7E-36 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS36090 b1ed31e23e9c7b8a7345a571b62e5342 430 Gene3D G3DSA:1.10.630.10 5 427 1.1E-69 T 29-03-2018 SMALA_RS36090 b1ed31e23e9c7b8a7345a571b62e5342 430 Pfam PF00067 Cytochrome P450 300 398 4.4E-21 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS36090 b1ed31e23e9c7b8a7345a571b62e5342 430 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 371 380 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMALA_RS36090 b1ed31e23e9c7b8a7345a571b62e5342 430 PRINTS PR00385 P450 superfamily signature 303 314 4.3E-6 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS36090 b1ed31e23e9c7b8a7345a571b62e5342 430 PRINTS PR00385 P450 superfamily signature 268 285 4.3E-6 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS36090 b1ed31e23e9c7b8a7345a571b62e5342 430 PRINTS PR00385 P450 superfamily signature 369 378 4.3E-6 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS36090 b1ed31e23e9c7b8a7345a571b62e5342 430 PRINTS PR00385 P450 superfamily signature 378 389 4.3E-6 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS36090 b1ed31e23e9c7b8a7345a571b62e5342 430 SUPERFAMILY SSF48264 15 426 1.96E-82 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS30855 83c107b2205930835dea8715011c7f96 376 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 1 372 2.8E-114 T 29-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 SMALA_RS30855 83c107b2205930835dea8715011c7f96 376 Pfam PF02595 Glycerate kinase family 1 373 2.0E-128 T 29-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 SMALA_RS30855 83c107b2205930835dea8715011c7f96 376 PIRSF PIRSF006078 1 376 7.7E-115 T 29-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 SMALA_RS30855 83c107b2205930835dea8715011c7f96 376 SUPERFAMILY SSF110738 1 372 6.93E-110 T 29-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 SMALA_RS30855 83c107b2205930835dea8715011c7f96 376 Gene3D G3DSA:3.90.1510.10 43 277 4.8E-85 T 29-03-2018 IPR018193 Glycerate kinase, flavodoxin-like domain GO:0008887|GO:0031388 SMALA_RS29110 47f7b826f9fe993393c4558d0e556c24 264 Pfam PF01551 Peptidase family M23 156 252 7.4E-30 T 29-03-2018 IPR016047 Peptidase M23 SMALA_RS29110 47f7b826f9fe993393c4558d0e556c24 264 Gene3D G3DSA:2.70.70.10 66 260 1.2E-43 T 29-03-2018 SMALA_RS29110 47f7b826f9fe993393c4558d0e556c24 264 SUPERFAMILY SSF51261 86 257 4.39E-44 T 29-03-2018 IPR011055 Duplicated hybrid motif SMALA_RS35645 fd33074b4bdc0a8ce6df8e049f3f9049 194 Gene3D G3DSA:3.40.430.10 2 191 4.5E-31 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 SMALA_RS35645 fd33074b4bdc0a8ce6df8e049f3f9049 194 SUPERFAMILY SSF53597 3 191 1.96E-23 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 SMALA_RS35645 fd33074b4bdc0a8ce6df8e049f3f9049 194 Pfam PF01872 RibD C-terminal domain 5 184 6.6E-19 T 29-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 SMALA_RS31590 3da957d28f56a171a030f671a6c34b86 256 SUPERFAMILY SSF46785 4 73 1.22E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS31590 3da957d28f56a171a030f671a6c34b86 256 SMART SM00346 2 93 1.9E-10 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMALA_RS31590 3da957d28f56a171a030f671a6c34b86 256 Pfam PF09339 IclR helix-turn-helix domain 4 56 2.5E-11 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMALA_RS31590 3da957d28f56a171a030f671a6c34b86 256 SUPERFAMILY SSF55781 62 247 5.23E-39 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS31590 3da957d28f56a171a030f671a6c34b86 256 Gene3D G3DSA:3.30.450.40 77 253 4.6E-42 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS31590 3da957d28f56a171a030f671a6c34b86 256 Pfam PF01614 Bacterial transcriptional regulator 121 240 1.4E-19 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal SMALA_RS31590 3da957d28f56a171a030f671a6c34b86 256 Gene3D G3DSA:1.10.10.10 3 65 3.4E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS31345 a43bf1de7dfbf8fc56f346528fc09d26 509 ProSitePatterns PS00211 ABC transporters family signature. 408 422 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS31345 a43bf1de7dfbf8fc56f346528fc09d26 509 Pfam PF00005 ABC transporter 27 177 4.2E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS31345 a43bf1de7dfbf8fc56f346528fc09d26 509 Pfam PF00005 ABC transporter 282 435 3.5E-20 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS31345 a43bf1de7dfbf8fc56f346528fc09d26 509 Gene3D G3DSA:3.40.50.300 8 236 1.3E-51 T 29-03-2018 SMALA_RS31345 a43bf1de7dfbf8fc56f346528fc09d26 509 Gene3D G3DSA:3.40.50.300 266 498 3.2E-42 T 29-03-2018 SMALA_RS31345 a43bf1de7dfbf8fc56f346528fc09d26 509 SMART SM00382 36 225 1.3E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS31345 a43bf1de7dfbf8fc56f346528fc09d26 509 SMART SM00382 290 484 3.9E-6 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS31345 a43bf1de7dfbf8fc56f346528fc09d26 509 SUPERFAMILY SSF52540 10 232 5.66E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS31345 a43bf1de7dfbf8fc56f346528fc09d26 509 SUPERFAMILY SSF52540 261 496 2.19E-47 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS11525 04001edbfb8a1a3650fd4e935d47d4dc 136 Gene3D G3DSA:3.40.1490.10 5 134 6.4E-44 T 29-03-2018 IPR023476 Peptidyl-tRNA hydrolase II domain MetaCyc: PWY-6308 SMALA_RS11525 04001edbfb8a1a3650fd4e935d47d4dc 136 SUPERFAMILY SSF102462 2 135 1.57E-42 T 29-03-2018 IPR023476 Peptidyl-tRNA hydrolase II domain MetaCyc: PWY-6308 SMALA_RS11525 04001edbfb8a1a3650fd4e935d47d4dc 136 Pfam PF09391 Protein of unknown function (DUF2000) 5 135 1.1E-40 T 29-03-2018 IPR018988 Protein of unknown function DUF2000 SMALA_RS11970 d461b7cf1c4d59f1f270f95ec119ab4b 327 Pfam PF14472 Domain of unknown function (DUF4429) 12 106 3.2E-16 T 29-03-2018 IPR027860 Domain of unknown function DUF4429 SMALA_RS11970 d461b7cf1c4d59f1f270f95ec119ab4b 327 Pfam PF14472 Domain of unknown function (DUF4429) 139 264 3.8E-40 T 29-03-2018 IPR027860 Domain of unknown function DUF4429 SMALA_RS11970 d461b7cf1c4d59f1f270f95ec119ab4b 327 Pfam PF09851 Short C-terminal domain 297 324 6.3E-7 T 29-03-2018 IPR018649 SHOCT domain SMALA_RS38950 4ac6f2946bb511973f11b41b27bf9c5f 388 Gene3D G3DSA:1.10.150.20 123 239 8.0E-4 T 29-03-2018 SMALA_RS38950 4ac6f2946bb511973f11b41b27bf9c5f 388 Pfam PF01548 Transposase 4 158 2.4E-21 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 SMALA_RS38950 4ac6f2946bb511973f11b41b27bf9c5f 388 Pfam PF02371 Transposase IS116/IS110/IS902 family 222 306 6.0E-22 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 SMALA_RS16075 7ce4640a7da4223d925cd701ffad6e3a 261 SUPERFAMILY SSF53697 74 221 2.51E-7 T 29-03-2018 SMALA_RS16075 7ce4640a7da4223d925cd701ffad6e3a 261 Gene3D G3DSA:1.10.10.10 1 82 8.0E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS16075 7ce4640a7da4223d925cd701ffad6e3a 261 Pfam PF01418 Helix-turn-helix domain, rpiR family 1 59 2.6E-10 T 29-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 SMALA_RS16075 7ce4640a7da4223d925cd701ffad6e3a 261 SUPERFAMILY SSF46689 1 59 5.55E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS16075 7ce4640a7da4223d925cd701ffad6e3a 261 Gene3D G3DSA:3.40.50.10490 83 256 7.9E-11 T 29-03-2018 SMALA_RS25615 d3ba5c6e89090abe748b34eb98c032b4 237 PIRSF PIRSF026671 10 220 2.8E-39 T 29-03-2018 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 SMALA_RS25615 d3ba5c6e89090abe748b34eb98c032b4 237 Gene3D G3DSA:3.30.1380.10 41 213 1.5E-36 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 SMALA_RS25615 d3ba5c6e89090abe748b34eb98c032b4 237 Hamap MF_01924 D-alanyl-D-alanine dipeptidase [ddpX]. 1 214 21.691 T 29-03-2018 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 SMALA_RS25615 d3ba5c6e89090abe748b34eb98c032b4 237 Pfam PF01427 D-ala-D-ala dipeptidase 77 211 3.3E-15 T 29-03-2018 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 SMALA_RS25615 d3ba5c6e89090abe748b34eb98c032b4 237 SUPERFAMILY SSF55166 40 211 4.45E-40 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 SMALA_RS12645 9fd967813b8a1e506f4b4de8ba3e1a7d 320 SUPERFAMILY SSF52540 50 276 5.88E-25 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS12645 9fd967813b8a1e506f4b4de8ba3e1a7d 320 Gene3D G3DSA:3.40.50.300 46 287 4.2E-26 T 29-03-2018 SMALA_RS12645 9fd967813b8a1e506f4b4de8ba3e1a7d 320 Pfam PF07728 AAA domain (dynein-related subfamily) 65 194 2.5E-7 T 29-03-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 SMALA_RS12645 9fd967813b8a1e506f4b4de8ba3e1a7d 320 SMART SM00382 61 248 5.2E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS24390 1b7f2950fe72db6246c785332ab11153 287 Pfam PF01061 ABC-2 type transporter 30 242 6.4E-28 T 29-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 SMALA_RS24390 1b7f2950fe72db6246c785332ab11153 287 PIRSF PIRSF006648 2 287 7.0E-73 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMALA_RS23095 ae49eaace1ed245986197955d40197d8 164 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 36 71 1.2E-15 T 29-03-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal SMALA_RS23095 ae49eaace1ed245986197955d40197d8 164 SUPERFAMILY SSF50249 21 141 3.08E-37 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMALA_RS23095 ae49eaace1ed245986197955d40197d8 164 Gene3D G3DSA:2.40.50.140 76 146 1.5E-17 T 29-03-2018 SMALA_RS23095 ae49eaace1ed245986197955d40197d8 164 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 73 138 5.9E-20 T 29-03-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal SMALA_RS22810 3f3cb869f8bc1bb05ae5fe2707f4a618 172 SUPERFAMILY SSF52540 26 116 3.25E-12 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS22810 3f3cb869f8bc1bb05ae5fe2707f4a618 172 Gene3D G3DSA:3.40.50.300 3 169 5.4E-46 T 29-03-2018 SMALA_RS22810 3f3cb869f8bc1bb05ae5fe2707f4a618 172 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 10 131 1.2E-29 T 29-03-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 SMALA_RS22810 3f3cb869f8bc1bb05ae5fe2707f4a618 172 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 13 133 2.1E-25 T 29-03-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 SMALA_RS03565 ce25481c76bf83f1e3e52558db4a8a54 240 Pfam PF06149 Protein of unknown function (DUF969) 1 217 3.7E-86 T 29-03-2018 IPR010374 Protein of unknown function DUF969 SMALA_RS24775 9ea50f936c22aebfc3f392a32e807641 318 SMART SM00244 86 250 2.4E-7 T 29-03-2018 IPR001107 Band 7 domain SMALA_RS24775 9ea50f936c22aebfc3f392a32e807641 318 Pfam PF01145 SPFH domain / Band 7 family 90 259 4.3E-21 T 29-03-2018 IPR001107 Band 7 domain SMALA_RS24775 9ea50f936c22aebfc3f392a32e807641 318 SUPERFAMILY SSF117892 124 252 1.83E-7 T 29-03-2018 IPR001107 Band 7 domain SMALA_RS15770 2f2898b199049d655dfb15267322d414 109 Pfam PF12728 Helix-turn-helix domain 56 104 6.9E-13 T 29-03-2018 SMALA_RS15770 2f2898b199049d655dfb15267322d414 109 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 56 102 1.6E-10 T 29-03-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 SMALA_RS15770 2f2898b199049d655dfb15267322d414 109 Gene3D G3DSA:1.10.10.10 55 109 2.6E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS05955 143c9dfdd214257e5cb0cb1c2f1d5381 93 Pfam PF02583 Metal-sensitive transcriptional repressor 11 81 6.4E-26 T 29-03-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 SMALA_RS38650 e28d7a7eef60a2692fdf8fde46aae7e4 385 Gene3D G3DSA:3.40.50.720 1 55 2.9E-7 T 29-03-2018 SMALA_RS38650 e28d7a7eef60a2692fdf8fde46aae7e4 385 Gene3D G3DSA:3.30.9.10 81 156 3.2E-5 T 29-03-2018 SMALA_RS38650 e28d7a7eef60a2692fdf8fde46aae7e4 385 SUPERFAMILY SSF51905 313 367 5.61E-48 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS38650 e28d7a7eef60a2692fdf8fde46aae7e4 385 SUPERFAMILY SSF51905 2 215 5.61E-48 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS38650 e28d7a7eef60a2692fdf8fde46aae7e4 385 Gene3D G3DSA:3.30.9.10 157 312 3.3E-21 T 29-03-2018 SMALA_RS38650 e28d7a7eef60a2692fdf8fde46aae7e4 385 Pfam PF01266 FAD dependent oxidoreductase 2 349 2.3E-43 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 SMALA_RS42975 e1da5f53c71944c46abff9141afb30fc 226 SUPERFAMILY SSF52980 94 200 7.51E-12 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 SMALA_RS42975 e1da5f53c71944c46abff9141afb30fc 226 Gene3D G3DSA:3.40.1350.10 84 203 6.2E-17 T 29-03-2018 SMALA_RS42975 e1da5f53c71944c46abff9141afb30fc 226 Pfam PF04471 Restriction endonuclease 88 200 2.3E-19 T 29-03-2018 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 SMALA_RS08990 237e03fd64dbde9cda066b79b38aec50 67 Pfam PF04149 Domain of unknown function (DUF397) 9 60 4.6E-22 T 29-03-2018 IPR007278 Domain of unknown function DUF397 SMALA_RS19625 7be8105d9c300f71b37f2baa38ee1531 445 Gene3D G3DSA:1.20.1250.20 234 444 6.6E-11 T 29-03-2018 SMALA_RS19625 7be8105d9c300f71b37f2baa38ee1531 445 SUPERFAMILY SSF103473 18 436 1.01E-22 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS19625 7be8105d9c300f71b37f2baa38ee1531 445 Gene3D G3DSA:1.20.1250.20 3 209 2.7E-12 T 29-03-2018 SMALA_RS24030 8339d439acc8d53a3e64a90448eecc6d 326 Pfam PF00487 Fatty acid desaturase 62 280 6.0E-21 T 29-03-2018 IPR005804 Fatty acid desaturase domain GO:0006629 SMALA_RS24030 8339d439acc8d53a3e64a90448eecc6d 326 PRINTS PR00075 Fatty acid desaturase family 1 signature 264 278 2.7E-16 T 29-03-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 SMALA_RS24030 8339d439acc8d53a3e64a90448eecc6d 326 PRINTS PR00075 Fatty acid desaturase family 1 signature 61 83 2.7E-16 T 29-03-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 SMALA_RS24030 8339d439acc8d53a3e64a90448eecc6d 326 PRINTS PR00075 Fatty acid desaturase family 1 signature 84 104 2.7E-16 T 29-03-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 SMALA_RS24030 8339d439acc8d53a3e64a90448eecc6d 326 PRINTS PR00075 Fatty acid desaturase family 1 signature 221 242 2.7E-16 T 29-03-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 SMALA_RS13410 bc77f19fe9aac1176432018313aaf294 179 Pfam PF14279 HNH endonuclease 83 128 2.2E-13 T 29-03-2018 IPR029471 HNH endonuclease 5 SMALA_RS13410 bc77f19fe9aac1176432018313aaf294 179 SMART SM00507 70 119 1.6E-14 T 29-03-2018 IPR003615 HNH nuclease SMALA_RS13410 bc77f19fe9aac1176432018313aaf294 179 Gene3D G3DSA:3.40.1800.10 66 136 4.3E-21 T 29-03-2018 SMALA_RS38000 fc2692d507ddc47ca9ad30088cc5a881 238 Pfam PF01925 Sulfite exporter TauE/SafE 9 230 1.6E-19 T 29-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 SMALA_RS04370 ab5c07699dd1bbd67a35eb18f01152f8 688 Pfam PF02543 Carbamoyltransferase N-terminus 27 344 1.7E-60 T 29-03-2018 IPR003696 Carbamoyltransferase GO:0003824|GO:0009058 SMALA_RS04370 ab5c07699dd1bbd67a35eb18f01152f8 688 Pfam PF16861 Carbamoyltransferase C-terminus 400 571 1.8E-63 T 29-03-2018 IPR031730 Carbamoyltransferase, C-terminal SMALA_RS04370 ab5c07699dd1bbd67a35eb18f01152f8 688 SUPERFAMILY SSF53067 32 98 4.53E-16 T 29-03-2018 SMALA_RS04370 ab5c07699dd1bbd67a35eb18f01152f8 688 SUPERFAMILY SSF53067 252 350 4.53E-16 T 29-03-2018 SMALA_RS04370 ab5c07699dd1bbd67a35eb18f01152f8 688 SUPERFAMILY SSF53067 134 218 4.53E-16 T 29-03-2018 SMALA_RS04370 ab5c07699dd1bbd67a35eb18f01152f8 688 Gene3D G3DSA:3.30.420.40 3 154 1.6E-24 T 29-03-2018 SMALA_RS03860 6dc713ff2fd870f2b44778496ddea236 149 SUPERFAMILY SSF51206 4 139 1.83E-23 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like SMALA_RS03860 6dc713ff2fd870f2b44778496ddea236 149 SMART SM00100 4 122 8.7E-8 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain SMALA_RS03860 6dc713ff2fd870f2b44778496ddea236 149 Gene3D G3DSA:2.60.120.10 2 141 6.2E-19 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SMALA_RS03860 6dc713ff2fd870f2b44778496ddea236 149 Pfam PF00027 Cyclic nucleotide-binding domain 23 110 5.7E-13 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain SMALA_RS01680 06637abc07fdac5d19fe2c94ff14293a 486 Pfam PF07905 Purine catabolism regulatory protein-like family 13 130 3.8E-28 T 29-03-2018 IPR012914 Purine catabolism PurC-like domain SMALA_RS01680 06637abc07fdac5d19fe2c94ff14293a 486 Gene3D G3DSA:1.10.10.60 395 456 5.8E-5 T 29-03-2018 SMALA_RS01680 06637abc07fdac5d19fe2c94ff14293a 486 Pfam PF13556 PucR C-terminal helix-turn-helix domain 420 478 3.1E-18 T 29-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain SMALA_RS16990 d27b21d3b7b5beaac9955b1079739f4c 424 SUPERFAMILY SSF55874 299 418 1.03E-12 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS16990 d27b21d3b7b5beaac9955b1079739f4c 424 Pfam PF13581 Histidine kinase-like ATPase domain 293 384 5.2E-7 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS16990 d27b21d3b7b5beaac9955b1079739f4c 424 Gene3D G3DSA:3.30.565.10 300 424 2.3E-14 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS16990 d27b21d3b7b5beaac9955b1079739f4c 424 Gene3D G3DSA:1.20.1250.20 26 299 4.5E-4 T 29-03-2018 SMALA_RS16990 d27b21d3b7b5beaac9955b1079739f4c 424 Pfam PF04024 PspC domain 15 70 2.9E-14 T 29-03-2018 IPR007168 Phage shock protein, PspC, N-terminal SMALA_RS21520 0811e1885263690c9986a9dcf5895c8c 313 Gene3D G3DSA:3.40.50.1820 19 312 1.9E-32 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS21520 0811e1885263690c9986a9dcf5895c8c 313 SUPERFAMILY SSF53474 23 139 5.94E-32 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS21520 0811e1885263690c9986a9dcf5895c8c 313 SUPERFAMILY SSF53474 181 308 5.94E-32 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS21520 0811e1885263690c9986a9dcf5895c8c 313 Pfam PF12697 Alpha/beta hydrolase family 54 292 3.2E-10 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS06370 bc854fced361a1eb0b5b8e9fee7bbf65 401 Pfam PF13795 HupE / UreJ protein 204 372 2.8E-36 T 29-03-2018 IPR032809 Putative HupE/UreJ protein SMALA_RS34785 ce63594a442dfbcfbb98cc45d74a1c64 100 SUPERFAMILY SSF143120 5 52 1.26E-11 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM SMALA_RS34785 ce63594a442dfbcfbb98cc45d74a1c64 100 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 4 51 8.8E-17 T 29-03-2018 SMALA_RS34785 ce63594a442dfbcfbb98cc45d74a1c64 100 Gene3D G3DSA:3.40.1620.10 3 51 4.9E-17 T 29-03-2018 SMALA_RS34785 ce63594a442dfbcfbb98cc45d74a1c64 100 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 5 54 1.6E-14 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM SMALA_RS03085 13bb0b62a7009f5e76918333ed9f1d86 337 Gene3D G3DSA:3.40.50.2300 145 301 7.5E-23 T 29-03-2018 SMALA_RS03085 13bb0b62a7009f5e76918333ed9f1d86 337 SUPERFAMILY SSF53822 29 329 4.35E-54 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SMALA_RS03085 13bb0b62a7009f5e76918333ed9f1d86 337 Pfam PF13407 Periplasmic binding protein domain 32 292 4.1E-44 T 29-03-2018 IPR025997 Periplasmic binding protein SMALA_RS03085 13bb0b62a7009f5e76918333ed9f1d86 337 Gene3D G3DSA:3.40.50.2300 25 144 6.2E-21 T 29-03-2018 SMALA_RS26055 a62d847779db4f9c3335fb9666611cf8 209 Pfam PF01863 Protein of unknown function DUF45 115 189 3.8E-23 T 29-03-2018 IPR002725 Protein of unknown function DUF45 SMALA_RS20735 1c09deebff6e1e142e7f949b48dc8883 296 Pfam PF06240 Carbon monoxide dehydrogenase subunit G (CoxG) 7 139 4.0E-9 T 29-03-2018 IPR010419 Carbon monoxide dehydrogenase subunit G SMALA_RS20735 1c09deebff6e1e142e7f949b48dc8883 296 Gene3D G3DSA:3.30.530.20 1 155 8.5E-19 T 29-03-2018 IPR023393 START-like domain SMALA_RS20735 1c09deebff6e1e142e7f949b48dc8883 296 SUPERFAMILY SSF55961 1 143 1.65E-18 T 29-03-2018 SMALA_RS14795 518e882eed243e174f213a6fc230cf05 276 Gene3D G3DSA:1.10.10.10 35 271 2.4E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS14795 518e882eed243e174f213a6fc230cf05 276 SMART SM00421 217 266 0.0034 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS14795 518e882eed243e174f213a6fc230cf05 276 SUPERFAMILY SSF46894 217 272 2.24E-8 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS25295 4f685143a8be52548e368569b5dc7da5 420 SUPERFAMILY SSF56059 86 337 6.15E-28 T 29-03-2018 SMALA_RS25295 4f685143a8be52548e368569b5dc7da5 420 Pfam PF13535 ATP-grasp domain 143 294 1.3E-21 T 29-03-2018 SMALA_RS25295 4f685143a8be52548e368569b5dc7da5 420 Gene3D G3DSA:3.40.50.20 1 111 1.7E-6 T 29-03-2018 SMALA_RS25295 4f685143a8be52548e368569b5dc7da5 420 Gene3D G3DSA:3.30.470.20 112 416 6.1E-28 T 29-03-2018 SMALA_RS31785 a03ea3500be5972266ed50b661e4cee3 69 Pfam PF00741 Gas vesicle protein 19 57 3.9E-14 T 29-03-2018 IPR000638 Gas vesicle protein GvpA GO:0005198|GO:0012506 SMALA_RS01270 28b723d29d82a55e72c0213977166e37 418 Gene3D G3DSA:1.10.630.10 2 415 1.3E-82 T 29-03-2018 SMALA_RS01270 28b723d29d82a55e72c0213977166e37 418 PRINTS PR00359 B-class P450 signature 159 174 2.1E-56 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS01270 28b723d29d82a55e72c0213977166e37 418 PRINTS PR00359 B-class P450 signature 332 347 2.1E-56 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS01270 28b723d29d82a55e72c0213977166e37 418 PRINTS PR00359 B-class P450 signature 304 331 2.1E-56 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS01270 28b723d29d82a55e72c0213977166e37 418 PRINTS PR00359 B-class P450 signature 353 362 2.1E-56 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS01270 28b723d29d82a55e72c0213977166e37 418 PRINTS PR00359 B-class P450 signature 142 158 2.1E-56 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS01270 28b723d29d82a55e72c0213977166e37 418 PRINTS PR00359 B-class P450 signature 362 373 2.1E-56 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS01270 28b723d29d82a55e72c0213977166e37 418 PRINTS PR00359 B-class P450 signature 95 106 2.1E-56 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS01270 28b723d29d82a55e72c0213977166e37 418 PRINTS PR00359 B-class P450 signature 196 218 2.1E-56 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS01270 28b723d29d82a55e72c0213977166e37 418 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 355 364 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMALA_RS01270 28b723d29d82a55e72c0213977166e37 418 SUPERFAMILY SSF48264 13 414 1.31E-100 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS01270 28b723d29d82a55e72c0213977166e37 418 Pfam PF00067 Cytochrome P450 181 384 1.7E-25 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS01270 28b723d29d82a55e72c0213977166e37 418 PRINTS PR00385 P450 superfamily signature 251 268 1.1E-7 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS01270 28b723d29d82a55e72c0213977166e37 418 PRINTS PR00385 P450 superfamily signature 286 297 1.1E-7 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS01270 28b723d29d82a55e72c0213977166e37 418 PRINTS PR00385 P450 superfamily signature 353 362 1.1E-7 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS01270 28b723d29d82a55e72c0213977166e37 418 PRINTS PR00385 P450 superfamily signature 362 373 1.1E-7 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS31720 d1ecdac2a9146e7001903f8be30c86b1 209 TIGRFAM TIGR00681 kdpC: K+-transporting ATPase, C subunit 10 207 2.3E-53 T 29-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 SMALA_RS31720 d1ecdac2a9146e7001903f8be30c86b1 209 PIRSF PIRSF001296 8 209 1.9E-67 T 29-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 SMALA_RS31720 d1ecdac2a9146e7001903f8be30c86b1 209 Hamap MF_00276 Potassium-transporting ATPase KdpC subunit [kdpC]. 9 208 34.294 T 29-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 SMALA_RS31720 d1ecdac2a9146e7001903f8be30c86b1 209 Pfam PF02669 K+-transporting ATPase, c chain 14 206 3.4E-68 T 29-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 SMALA_RS39560 b7c9b29f4cb48b008e4e6a92d8b20787 164 Gene3D G3DSA:2.30.110.10 2 160 8.1E-18 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS39560 b7c9b29f4cb48b008e4e6a92d8b20787 164 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 30 152 4.2E-27 T 29-03-2018 IPR024747 Pyridoxamine 5'-phosphate oxidase-related SMALA_RS39560 b7c9b29f4cb48b008e4e6a92d8b20787 164 SUPERFAMILY SSF50475 27 154 3.23E-18 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS20225 ca50b7e56d9b0d39b3acf49916c5732c 119 Pfam PF05331 Protein of unknown function (DUF742) 8 119 1.2E-32 T 29-03-2018 IPR007995 Protein of unknown function DUF742 SMALA_RS36105 9155d59dce56101c0d4bccefa14fd299 273 SUPERFAMILY SSF52096 21 245 3.58E-67 T 29-03-2018 IPR029045 ClpP/crotonase-like domain SMALA_RS36105 9155d59dce56101c0d4bccefa14fd299 273 Gene3D G3DSA:3.90.226.10 7 266 1.2E-63 T 29-03-2018 SMALA_RS36105 9155d59dce56101c0d4bccefa14fd299 273 Pfam PF00378 Enoyl-CoA hydratase/isomerase 27 242 1.0E-39 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 SMALA_RS36105 9155d59dce56101c0d4bccefa14fd299 273 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 114 134 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 SMALA_RS01150 bfe8f47ae74acbe7cac3e88cc6b52b9b 342 Gene3D G3DSA:1.10.600.10 4 342 4.7E-86 T 29-03-2018 IPR008949 Isoprenoid synthase domain SMALA_RS01150 bfe8f47ae74acbe7cac3e88cc6b52b9b 342 SUPERFAMILY SSF48576 12 341 6.3E-79 T 29-03-2018 IPR008949 Isoprenoid synthase domain SMALA_RS01150 bfe8f47ae74acbe7cac3e88cc6b52b9b 342 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 89 103 - T 29-03-2018 IPR033749 Polyprenyl synthetase, conserved site SMALA_RS01150 bfe8f47ae74acbe7cac3e88cc6b52b9b 342 Pfam PF00348 Polyprenyl synthetase 38 279 2.9E-52 T 29-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 SMALA_RS40180 3eaf4ef2e09917e6925e08bf192da4d9 302 Gene3D G3DSA:3.40.50.150 4 281 6.5E-46 T 29-03-2018 SMALA_RS40180 3eaf4ef2e09917e6925e08bf192da4d9 302 Pfam PF04072 Leucine carboxyl methyltransferase 22 202 2.7E-50 T 29-03-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 SMALA_RS40180 3eaf4ef2e09917e6925e08bf192da4d9 302 SUPERFAMILY SSF53335 18 298 2.08E-62 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS40180 3eaf4ef2e09917e6925e08bf192da4d9 302 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 20 279 7.7E-77 T 29-03-2018 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 SMALA_RS30565 3a651f207f929a2bf59d8973132e2d7e 187 Gene3D G3DSA:3.40.430.10 2 183 1.1E-35 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 SMALA_RS30565 3a651f207f929a2bf59d8973132e2d7e 187 SUPERFAMILY SSF53597 2 185 1.44E-30 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 SMALA_RS30565 3a651f207f929a2bf59d8973132e2d7e 187 Pfam PF01872 RibD C-terminal domain 3 179 1.7E-21 T 29-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 SMALA_RS26900 fc178d420617ed77cc604657fca87d50 186 Gene3D G3DSA:1.20.5.620 77 137 8.9E-11 T 29-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain SMALA_RS26900 fc178d420617ed77cc604657fca87d50 186 SUPERFAMILY SSF81573 78 136 7.98E-11 T 29-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain SMALA_RS26900 fc178d420617ed77cc604657fca87d50 186 Pfam PF00430 ATP synthase B/B' CF(0) 22 151 1.7E-27 T 29-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 SMALA_RS26900 fc178d420617ed77cc604657fca87d50 186 Hamap MF_01398 ATP synthase subunit b [atpF]. 9 153 12.354 T 29-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 SMALA_RS26900 fc178d420617ed77cc604657fca87d50 186 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 26 172 2.8E-26 T 29-03-2018 IPR005864 ATP synthase, F0 complex, subunit b, bacterial GO:0015078|GO:0015986|GO:0045263 SMALA_RS33640 528b9a38f60ab3f2af3f085a591e24ba 244 SUPERFAMILY SSF53335 5 242 2.92E-50 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS33640 528b9a38f60ab3f2af3f085a591e24ba 244 Pfam PF02353 Mycolic acid cyclopropane synthetase 8 238 2.8E-48 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS33640 528b9a38f60ab3f2af3f085a591e24ba 244 Gene3D G3DSA:3.40.50.150 3 243 2.5E-35 T 29-03-2018 SMALA_RS33640 528b9a38f60ab3f2af3f085a591e24ba 244 PIRSF PIRSF003085 5 244 9.2E-53 T 29-03-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 SMALA_RS17365 ffe93fbbcfecb79d5416ca11bf864180 288 Hamap MF_00996 1,4-dihydroxy-6-naphtoate synthase [mqnD]. 4 278 39.641 T 29-03-2018 IPR030869 1,4-dihydroxy-6-naphtoate synthase GO:0009234|GO:0016829 SMALA_RS17365 ffe93fbbcfecb79d5416ca11bf864180 288 Pfam PF02621 Menaquinone biosynthesis 5 272 5.0E-88 T 29-03-2018 IPR003773 Menaquinone biosynthesis enzyme SMALA_RS17365 ffe93fbbcfecb79d5416ca11bf864180 288 Gene3D G3DSA:3.40.190.10 182 282 4.3E-14 T 29-03-2018 SMALA_RS17365 ffe93fbbcfecb79d5416ca11bf864180 288 Gene3D G3DSA:3.40.190.10 2 181 3.3E-83 T 29-03-2018 SMALA_RS17365 ffe93fbbcfecb79d5416ca11bf864180 288 SUPERFAMILY SSF53850 5 277 1.32E-81 T 29-03-2018 SMALA_RS21265 3ccff6424bfd4dd90fdd31387e25175c 631 SUPERFAMILY SSF52540 366 604 1.86E-5 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS18285 1b66807ca49cb2136293635f60274b39 488 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 41 163 1.2E-10 T 29-03-2018 SMALA_RS35325 4865f0ba2c4125e67f37b4a00c721ab4 102 Pfam PF05121 Gas vesicle protein K 12 96 1.1E-34 T 29-03-2018 IPR007805 Gas vesicle protein GvpK GO:0031412 SMALA_RS34755 a598bb11d264a4a041247cae10fb170f 142 SUPERFAMILY SSF55874 39 137 5.07E-13 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS34755 a598bb11d264a4a041247cae10fb170f 142 Gene3D G3DSA:3.30.565.10 2 141 3.6E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS34755 a598bb11d264a4a041247cae10fb170f 142 Pfam PF13581 Histidine kinase-like ATPase domain 12 133 2.1E-13 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS14425 642b85b4b9dcf63236edffbacd449149 560 Gene3D G3DSA:1.20.810.10 32 452 1.9E-97 T 29-03-2018 IPR027387 Cytochrome b/b6-like domain Reactome: R-HSA-611105 SMALA_RS14425 642b85b4b9dcf63236edffbacd449149 560 Pfam PF13631 Cytochrome b(N-terminal)/b6/petB 131 304 4.4E-54 T 29-03-2018 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 SMALA_RS14425 642b85b4b9dcf63236edffbacd449149 560 SUPERFAMILY SSF81342 30 307 7.53E-58 T 29-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 SMALA_RS33900 8b6f44bf7269ae20bb53f0c29dd596be 212 Pfam PF13649 Methyltransferase domain 50 141 2.8E-21 T 29-03-2018 SMALA_RS33900 8b6f44bf7269ae20bb53f0c29dd596be 212 SUPERFAMILY SSF53335 4 208 2.41E-40 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS33900 8b6f44bf7269ae20bb53f0c29dd596be 212 Gene3D G3DSA:3.40.50.150 8 210 2.4E-36 T 29-03-2018 SMALA_RS34355 ee6f5d0a2059283ae20eb9b9ed7b785a 206 SUPERFAMILY SSF50475 3 189 2.89E-49 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS34355 ee6f5d0a2059283ae20eb9b9ed7b785a 206 Gene3D G3DSA:2.30.110.10 13 183 3.7E-49 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS34355 ee6f5d0a2059283ae20eb9b9ed7b785a 206 Pfam PF01613 Flavin reductase like domain 24 158 1.0E-24 T 29-03-2018 IPR002563 Flavin reductase like domain GO:0010181 SMALA_RS34355 ee6f5d0a2059283ae20eb9b9ed7b785a 206 SMART SM00903 21 165 1.5E-14 T 29-03-2018 IPR002563 Flavin reductase like domain GO:0010181 SMALA_RS01550 2dbd73319d3fdbd978ced11868dea476 84 SUPERFAMILY SSF47336 5 78 6.54E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS01550 2dbd73319d3fdbd978ced11868dea476 84 Pfam PF00550 Phosphopantetheine attachment site 5 63 3.8E-6 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS01550 2dbd73319d3fdbd978ced11868dea476 84 Gene3D G3DSA:1.10.1200.10 1 80 2.8E-12 T 29-03-2018 SMALA_RS07570 b2fee9e1fd71551ec3f8f3ab02d41de0 95 Gene3D G3DSA:1.10.150.130 44 94 6.5E-5 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal SMALA_RS20800 d92cb42fe4b916a21710ae76ef9bf5c3 305 Gene3D G3DSA:3.40.50.300 1 270 6.2E-59 T 29-03-2018 SMALA_RS20800 d92cb42fe4b916a21710ae76ef9bf5c3 305 Pfam PF00005 ABC transporter 20 159 6.3E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS20800 d92cb42fe4b916a21710ae76ef9bf5c3 305 Pfam PF13732 Domain of unknown function (DUF4162) 212 289 1.3E-7 T 29-03-2018 IPR025302 Domain of unknown function DUF4162 SMALA_RS20800 d92cb42fe4b916a21710ae76ef9bf5c3 305 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS20800 d92cb42fe4b916a21710ae76ef9bf5c3 305 SMART SM00382 29 215 9.2E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS20800 d92cb42fe4b916a21710ae76ef9bf5c3 305 SUPERFAMILY SSF52540 4 219 1.45E-53 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS27455 3e2be3e9b240678433f6d604dbdd0eb6 208 SMART SM00644 62 193 2.0E-40 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 SMALA_RS27455 3e2be3e9b240678433f6d604dbdd0eb6 208 Gene3D G3DSA:3.40.80.10 22 208 3.3E-41 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 SMALA_RS27455 3e2be3e9b240678433f6d604dbdd0eb6 208 SUPERFAMILY SSF55846 62 206 7.85E-42 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 SMALA_RS27455 3e2be3e9b240678433f6d604dbdd0eb6 208 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 72 194 2.2E-30 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 SMALA_RS34810 6ed3951cfb245334fd7f1c2921c2cc7d 219 Pfam PF01730 UreF 29 169 2.0E-17 T 29-03-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 SMALA_RS34810 6ed3951cfb245334fd7f1c2921c2cc7d 219 PIRSF PIRSF009467 1 219 1.0E-46 T 29-03-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 SMALA_RS34810 6ed3951cfb245334fd7f1c2921c2cc7d 219 Hamap MF_01385 Urease accessory protein UreF [ureF]. 1 219 17.188 T 29-03-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 SMALA_RS34565 0c77174542ea837249d4f859a19d17a1 149 SUPERFAMILY SSF46785 12 146 1.55E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS34565 0c77174542ea837249d4f859a19d17a1 149 Gene3D G3DSA:1.10.10.10 2 109 3.7E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS34565 0c77174542ea837249d4f859a19d17a1 149 Pfam PF01047 MarR family 39 94 1.8E-8 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS34565 0c77174542ea837249d4f859a19d17a1 149 Gene3D G3DSA:1.10.287.100 110 146 1.8E-10 T 29-03-2018 SMALA_RS34565 0c77174542ea837249d4f859a19d17a1 149 SMART SM00347 30 131 4.3E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS20450 0fdaa5945334f5b5a88af8c0edd8657e 145 SUPERFAMILY SSF54427 8 142 7.86E-26 T 29-03-2018 IPR032710 NTF2-like domain SMALA_RS20450 0fdaa5945334f5b5a88af8c0edd8657e 145 Gene3D G3DSA:3.10.450.50 1 145 1.7E-23 T 29-03-2018 SMALA_RS20450 0fdaa5945334f5b5a88af8c0edd8657e 145 Pfam PF12680 SnoaL-like domain 13 129 1.3E-13 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain SMALA_RS25045 be57ad69b9b4ebb3213d6e8a6c3373bf 186 Pfam PF04229 GrpB protein 25 179 9.9E-45 T 29-03-2018 IPR007344 GrpB/Dephospho-CoA kinase SMALA_RS25045 be57ad69b9b4ebb3213d6e8a6c3373bf 186 Gene3D G3DSA:3.30.460.10 21 186 2.2E-46 T 29-03-2018 SMALA_RS25045 be57ad69b9b4ebb3213d6e8a6c3373bf 186 SUPERFAMILY SSF81301 29 182 3.6E-43 T 29-03-2018 SMALA_RS35090 a301a440e2f966eebaab44874c63ebc0 497 Pfam PF09362 Domain of unknown function (DUF1996) 253 475 1.1E-28 T 29-03-2018 IPR018535 Domain of unknown function DUF1996 SMALA_RS09705 5417786e6406543e57773be89d60c4e5 402 Pfam PF03747 ADP-ribosylglycohydrolase 18 356 1.4E-66 T 29-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 SMALA_RS09705 5417786e6406543e57773be89d60c4e5 402 SUPERFAMILY SSF101478 138 377 1.28E-59 T 29-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 SMALA_RS09705 5417786e6406543e57773be89d60c4e5 402 SUPERFAMILY SSF101478 13 109 1.28E-59 T 29-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 SMALA_RS09705 5417786e6406543e57773be89d60c4e5 402 Gene3D G3DSA:1.10.4080.10 8 390 2.9E-76 T 29-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 SMALA_RS41675 0479d87cf2c679bee345665fddbd0cb6 439 Gene3D G3DSA:3.40.190.10 156 438 5.9E-50 T 29-03-2018 SMALA_RS41675 0479d87cf2c679bee345665fddbd0cb6 439 Pfam PF13416 Bacterial extracellular solute-binding protein 67 377 1.7E-33 T 29-03-2018 SMALA_RS41675 0479d87cf2c679bee345665fddbd0cb6 439 SUPERFAMILY SSF53850 56 431 1.22E-72 T 29-03-2018 SMALA_RS36445 e3c3266d47edf99170e42ad6a555fce5 475 PIRSF PIRSF002744 1 458 7.8E-93 T 29-03-2018 IPR026030 Purine-cytosine permease Fcy2/21/22 GO:0005215|GO:0016021|GO:0055085 SMALA_RS36445 e3c3266d47edf99170e42ad6a555fce5 475 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 25 417 2.5E-33 T 29-03-2018 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 SMALA_RS19650 db1332ee825f5d722b48f25a3acd3b21 229 SUPERFAMILY SSF88946 7 114 4.51E-30 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS19650 db1332ee825f5d722b48f25a3acd3b21 229 Pfam PF04542 Sigma-70 region 2 30 96 3.5E-17 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS19650 db1332ee825f5d722b48f25a3acd3b21 229 Pfam PF08281 Sigma-70, region 4 129 181 1.7E-15 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS19650 db1332ee825f5d722b48f25a3acd3b21 229 Gene3D G3DSA:1.10.1740.10 7 98 7.6E-27 T 29-03-2018 SMALA_RS19650 db1332ee825f5d722b48f25a3acd3b21 229 SUPERFAMILY SSF88659 123 185 3.71E-15 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS19650 db1332ee825f5d722b48f25a3acd3b21 229 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 24 182 1.2E-28 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS19650 db1332ee825f5d722b48f25a3acd3b21 229 Gene3D G3DSA:1.10.10.10 99 188 6.0E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS12115 775b4eb8c24207c8a0381bc866fb9493 405 Gene3D G3DSA:2.70.98.10 59 405 2.0E-122 T 29-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 SMALA_RS12115 775b4eb8c24207c8a0381bc866fb9493 405 Pfam PF01263 Aldose 1-epimerase 71 399 9.6E-96 T 29-03-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 SMALA_RS12115 775b4eb8c24207c8a0381bc866fb9493 405 SUPERFAMILY SSF74650 59 403 4.33E-117 T 29-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 SMALA_RS12115 775b4eb8c24207c8a0381bc866fb9493 405 PIRSF PIRSF005096 55 405 1.4E-131 T 29-03-2018 IPR015443 Aldose 1-epimerase GO:0016853|GO:0019318 KEGG: 00010+5.1.3.3|KEGG: 00052+5.1.3.3|MetaCyc: PWY-6317 SMALA_RS26630 b902cc732bc98edb5578b8dccc12643c 458 Gene3D G3DSA:3.50.50.60 3 363 4.9E-18 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS26630 b902cc732bc98edb5578b8dccc12643c 458 SUPERFAMILY SSF51905 2 161 7.22E-16 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS26630 b902cc732bc98edb5578b8dccc12643c 458 SUPERFAMILY SSF51905 286 361 7.22E-16 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS26630 b902cc732bc98edb5578b8dccc12643c 458 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 8.9E-6 T 29-03-2018 SMALA_RS26630 b902cc732bc98edb5578b8dccc12643c 458 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 306 322 8.9E-6 T 29-03-2018 SMALA_RS19940 eae65485df031655e26fb38c22d9d85e 410 SMART SM00752 20 369 1.4E-87 T 29-03-2018 IPR011020 HTTM Reactome: R-HSA-159740 SMALA_RS02395 afc1ab4618b81b9b4b2a97d2243e9cfe 608 Gene3D G3DSA:3.50.50.60 36 243 7.2E-30 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS02395 afc1ab4618b81b9b4b2a97d2243e9cfe 608 SUPERFAMILY SSF51905 404 530 6.62E-43 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS02395 afc1ab4618b81b9b4b2a97d2243e9cfe 608 SUPERFAMILY SSF51905 77 312 6.62E-43 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS02395 afc1ab4618b81b9b4b2a97d2243e9cfe 608 Gene3D G3DSA:3.50.50.60 245 607 1.6E-48 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS02395 afc1ab4618b81b9b4b2a97d2243e9cfe 608 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 76 267 2.7E-10 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS03920 8b08f01c4ecafba7c5a3103ba2d9dfdf 98 Pfam PF09851 Short C-terminal domain 59 84 2.6E-6 T 29-03-2018 IPR018649 SHOCT domain SMALA_RS25215 b0a5f2e2efa41619646940c2a4582023 306 Pfam PF03466 LysR substrate binding domain 101 236 3.3E-15 T 29-03-2018 IPR005119 LysR, substrate-binding SMALA_RS25215 b0a5f2e2efa41619646940c2a4582023 306 SUPERFAMILY SSF46785 11 102 8.82E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS25215 b0a5f2e2efa41619646940c2a4582023 306 Gene3D G3DSA:1.10.10.10 7 94 5.6E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS25215 b0a5f2e2efa41619646940c2a4582023 306 Gene3D G3DSA:3.40.190.10 101 180 1.7E-4 T 29-03-2018 SMALA_RS25215 b0a5f2e2efa41619646940c2a4582023 306 SUPERFAMILY SSF53850 102 290 3.8E-14 T 29-03-2018 SMALA_RS25215 b0a5f2e2efa41619646940c2a4582023 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 50 61 3.1E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS25215 b0a5f2e2efa41619646940c2a4582023 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 50 3.1E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS25215 b0a5f2e2efa41619646940c2a4582023 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 40 3.1E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS25215 b0a5f2e2efa41619646940c2a4582023 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 15 73 1.4E-19 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS25215 b0a5f2e2efa41619646940c2a4582023 306 Gene3D G3DSA:3.40.190.10 181 243 1.1E-9 T 29-03-2018 SMALA_RS36820 a15b52cb6af364678417929d2bd1daf3 250 Pfam PF03713 Domain of unknown function (DUF305) 79 247 3.0E-49 T 29-03-2018 IPR005183 Domain of unknown function DUF305 SMALA_RS36820 a15b52cb6af364678417929d2bd1daf3 250 Gene3D G3DSA:1.20.1260.10 71 250 2.6E-53 T 29-03-2018 IPR012347 Ferritin-related SMALA_RS32335 90a94c0b033dd382588f6192dca11203 382 SMART SM00331 124 361 3.1E-23 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS32335 90a94c0b033dd382588f6192dca11203 382 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 155 361 2.5E-34 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS32335 90a94c0b033dd382588f6192dca11203 382 Gene3D G3DSA:3.60.40.10 93 363 1.6E-19 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS03300 a08f1a4b511f4f21c88388a8c97502ed 500 SUPERFAMILY SSF55931 38 463 7.06E-48 T 29-03-2018 SMALA_RS03300 a08f1a4b511f4f21c88388a8c97502ed 500 PIRSF PIRSF012666 1 498 1.9E-205 T 29-03-2018 IPR016602 Uncharacterised conserved protein UCP012666 SMALA_RS39480 4379065de4c2b7f69311639c569e914b 340 Pfam PF04909 Amidohydrolase 3 329 2.0E-55 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 SMALA_RS39480 4379065de4c2b7f69311639c569e914b 340 Gene3D G3DSA:3.20.20.140 1 340 2.2E-60 T 29-03-2018 SMALA_RS39480 4379065de4c2b7f69311639c569e914b 340 SUPERFAMILY SSF51556 2 330 5.76E-84 T 29-03-2018 IPR032466 Metal-dependent hydrolase SMALA_RS42510 8459c7ca7da76ed3a4258140d066af3a 385 Gene3D G3DSA:1.10.540.10 24 122 5.4E-9 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS42510 8459c7ca7da76ed3a4258140d066af3a 385 SUPERFAMILY SSF56645 30 239 3.27E-23 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMALA_RS42510 8459c7ca7da76ed3a4258140d066af3a 385 Gene3D G3DSA:2.40.110.10 145 242 1.2E-7 T 29-03-2018 SMALA_RS42510 8459c7ca7da76ed3a4258140d066af3a 385 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 30 111 1.2E-6 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SMALA_RS34360 2c8cc1e60885a63173f6856a17db80d5 215 Pfam PF00702 haloacid dehalogenase-like hydrolase 68 172 6.3E-11 T 29-03-2018 SMALA_RS34360 2c8cc1e60885a63173f6856a17db80d5 215 SUPERFAMILY SSF56784 3 210 5.99E-34 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS34360 2c8cc1e60885a63173f6856a17db80d5 215 Gene3D G3DSA:3.40.50.1000 60 215 9.3E-28 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS34360 2c8cc1e60885a63173f6856a17db80d5 215 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 94 172 4.1E-7 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMALA_RS18900 4135d1bbc3dfe300615ff2aff86d21bb 353 SUPERFAMILY SSF51126 47 318 5.14E-20 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor SMALA_RS18900 4135d1bbc3dfe300615ff2aff86d21bb 353 Gene3D G3DSA:2.160.20.20 27 221 2.2E-17 T 29-03-2018 IPR012332 P22 tailspike C-terminal domain-like SMALA_RS30440 c3fb47c04e8e1a4e67dea64b925da0ed 591 Pfam PF07905 Purine catabolism regulatory protein-like family 6 120 1.2E-26 T 29-03-2018 IPR012914 Purine catabolism PurC-like domain SMALA_RS30440 c3fb47c04e8e1a4e67dea64b925da0ed 591 Gene3D G3DSA:1.10.10.60 518 569 1.2E-8 T 29-03-2018 SMALA_RS30440 c3fb47c04e8e1a4e67dea64b925da0ed 591 Pfam PF13556 PucR C-terminal helix-turn-helix domain 532 589 6.8E-22 T 29-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain SMALA_RS31645 af4ef4e6ec8ee57794714cfce4e78c92 638 SUPERFAMILY SSF51556 245 548 8.01E-29 T 29-03-2018 IPR032466 Metal-dependent hydrolase SMALA_RS31645 af4ef4e6ec8ee57794714cfce4e78c92 638 SUPERFAMILY SSF51556 105 169 8.01E-29 T 29-03-2018 IPR032466 Metal-dependent hydrolase SMALA_RS31645 af4ef4e6ec8ee57794714cfce4e78c92 638 SUPERFAMILY SSF51338 40 105 8.64E-16 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS31645 af4ef4e6ec8ee57794714cfce4e78c92 638 SUPERFAMILY SSF51338 548 591 8.64E-16 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS31645 af4ef4e6ec8ee57794714cfce4e78c92 638 Pfam PF07969 Amidohydrolase family 94 587 2.1E-82 T 29-03-2018 IPR013108 Amidohydrolase 3 SMALA_RS31645 af4ef4e6ec8ee57794714cfce4e78c92 638 Gene3D G3DSA:2.30.40.10 45 115 2.5E-16 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS31645 af4ef4e6ec8ee57794714cfce4e78c92 638 Gene3D G3DSA:2.30.40.10 528 596 9.8E-10 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS31645 af4ef4e6ec8ee57794714cfce4e78c92 638 Gene3D G3DSA:3.20.20.140 116 527 5.5E-44 T 29-03-2018 SMALA_RS34615 ac7737514b32afd74d4012e1f0894c3f 425 Gene3D G3DSA:3.40.630.30 250 388 5.4E-21 T 29-03-2018 SMALA_RS34615 ac7737514b32afd74d4012e1f0894c3f 425 SUPERFAMILY SSF55729 249 386 1.42E-20 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS34615 ac7737514b32afd74d4012e1f0894c3f 425 Pfam PF00583 Acetyltransferase (GNAT) family 315 382 2.8E-6 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SMALA_RS34615 ac7737514b32afd74d4012e1f0894c3f 425 Gene3D G3DSA:3.30.70.260 59 144 9.5E-10 T 29-03-2018 SMALA_RS09405 87cd68cf951c9baa2da2d4252f4d015e 277 Pfam PF09234 Domain of unknown function (DUF1963) 46 276 1.3E-36 T 29-03-2018 IPR015315 Protein of unknown function DUF1963 SMALA_RS09405 87cd68cf951c9baa2da2d4252f4d015e 277 Gene3D G3DSA:2.30.320.10 10 277 1.2E-50 T 29-03-2018 SMALA_RS09405 87cd68cf951c9baa2da2d4252f4d015e 277 SUPERFAMILY SSF103032 46 277 4.84E-28 T 29-03-2018 IPR015315 Protein of unknown function DUF1963 SMALA_RS40930 5c40d496a74dd9aad06d4ee9d21e4a01 85 SUPERFAMILY SSF47336 3 80 1.15E-17 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS40930 5c40d496a74dd9aad06d4ee9d21e4a01 85 Pfam PF00550 Phosphopantetheine attachment site 10 75 2.6E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS40930 5c40d496a74dd9aad06d4ee9d21e4a01 85 Gene3D G3DSA:1.10.1200.10 1 85 9.3E-18 T 29-03-2018 SMALA_RS18145 be8ccfb880f414979d86cf4fc020d0f3 567 Pfam PF12821 Threonine/Serine exporter, ThrE 413 538 1.7E-18 T 29-03-2018 IPR024528 Threonine/Serine exporter, ThrE SMALA_RS18145 be8ccfb880f414979d86cf4fc020d0f3 567 Pfam PF06738 Putative threonine/serine exporter 148 388 1.5E-60 T 29-03-2018 IPR010619 Putative threonine/serine exporter SMALA_RS09850 f45bc784a1ce8d8c42395d597233dc74 252 Pfam PF04402 Protein of unknown function (DUF541) 37 245 8.1E-31 T 29-03-2018 IPR007497 Protein of unknown function DUF541 SMALA_RS36835 3ee1b34b3e422df40b2fd0cfdd914339 176 Pfam PF02342 TerD domain 5 161 1.2E-20 T 29-03-2018 IPR003325 TerD domain GO:0006950 SMALA_RS36835 3ee1b34b3e422df40b2fd0cfdd914339 176 Gene3D G3DSA:2.60.60.30 7 169 1.2E-36 T 29-03-2018 SMALA_RS21605 43ff9f9f94e50ab52655279d42168cb4 250 Gene3D G3DSA:2.60.40.10 117 226 5.8E-4 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS21605 43ff9f9f94e50ab52655279d42168cb4 250 Pfam PF14016 Protein of unknown function (DUF4232) 110 231 1.8E-15 T 29-03-2018 IPR025326 Protein of unknown function DUF4232 SMALA_RS14350 ced67af55c7c4419026016279ec2b810 205 Gene3D G3DSA:3.90.70.10 53 205 9.4E-14 T 29-03-2018 SMALA_RS14350 ced67af55c7c4419026016279ec2b810 205 Pfam PF13529 Peptidase_C39 like family 9 174 5.8E-7 T 29-03-2018 SMALA_RS39765 3ef887c035efedd4af2b1f3c94ad5477 321 SUPERFAMILY SSF53474 45 319 4.74E-55 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS39765 3ef887c035efedd4af2b1f3c94ad5477 321 Pfam PF07859 alpha/beta hydrolase fold 85 294 1.8E-47 T 29-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 SMALA_RS39765 3ef887c035efedd4af2b1f3c94ad5477 321 Gene3D G3DSA:3.40.50.1820 1 321 1.3E-51 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS20080 3efaab225df81ae366c40e79a0ba35e0 328 SUPERFAMILY SSF54001 192 294 3.83E-5 T 29-03-2018 SMALA_RS20080 3efaab225df81ae366c40e79a0ba35e0 328 Gene3D G3DSA:3.90.1720.10 183 312 3.9E-10 T 29-03-2018 SMALA_RS03810 f61a8d3cc260766bd98658a0ad1a5f1f 704 Pfam PF13185 GAF domain 85 228 1.8E-18 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS03810 f61a8d3cc260766bd98658a0ad1a5f1f 704 Gene3D G3DSA:3.30.450.40 61 259 1.3E-34 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS03810 f61a8d3cc260766bd98658a0ad1a5f1f 704 SUPERFAMILY SSF55781 69 252 4.8E-32 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS03810 f61a8d3cc260766bd98658a0ad1a5f1f 704 SMART SM00065 86 237 3.0E-20 T 29-03-2018 IPR003018 GAF domain GO:0005515 SMALA_RS03810 f61a8d3cc260766bd98658a0ad1a5f1f 704 Pfam PF13556 PucR C-terminal helix-turn-helix domain 637 695 2.6E-17 T 29-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain SMALA_RS06170 e4b4afc5d1b441c90c9e90984b0e0fdd 280 Gene3D G3DSA:3.40.50.720 2 139 3.2E-15 T 29-03-2018 SMALA_RS06170 e4b4afc5d1b441c90c9e90984b0e0fdd 280 Gene3D G3DSA:3.90.25.10 140 277 1.2E-4 T 29-03-2018 SMALA_RS06170 e4b4afc5d1b441c90c9e90984b0e0fdd 280 SUPERFAMILY SSF51735 4 245 1.41E-33 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS06170 e4b4afc5d1b441c90c9e90984b0e0fdd 280 Pfam PF13460 NAD(P)H-binding 8 177 5.2E-13 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS03690 2b745855991344fceec3d8d1d2ba7507 549 Pfam PF13193 AMP-binding enzyme C-terminal domain 445 521 6.9E-18 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS03690 2b745855991344fceec3d8d1d2ba7507 549 Pfam PF00501 AMP-binding enzyme 10 435 1.1E-64 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS03690 2b745855991344fceec3d8d1d2ba7507 549 Gene3D G3DSA:3.40.50.980 3 176 1.7E-36 T 29-03-2018 SMALA_RS03690 2b745855991344fceec3d8d1d2ba7507 549 ProSitePatterns PS00455 Putative AMP-binding domain signature. 172 183 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS03690 2b745855991344fceec3d8d1d2ba7507 549 Gene3D G3DSA:2.30.38.10 354 427 5.8E-14 T 29-03-2018 SMALA_RS03690 2b745855991344fceec3d8d1d2ba7507 549 Gene3D G3DSA:3.30.300.30 432 540 2.1E-28 T 29-03-2018 SMALA_RS03690 2b745855991344fceec3d8d1d2ba7507 549 SUPERFAMILY SSF56801 4 533 1.01E-114 T 29-03-2018 SMALA_RS03690 2b745855991344fceec3d8d1d2ba7507 549 Gene3D G3DSA:3.40.50.980 177 353 3.6E-20 T 29-03-2018 SMALA_RS37875 43120f0d68cc01bd4a935d83c4fb1618 126 Pfam PF01638 HxlR-like helix-turn-helix 29 116 1.1E-28 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type SMALA_RS37875 43120f0d68cc01bd4a935d83c4fb1618 126 Gene3D G3DSA:1.10.10.10 27 124 8.7E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS37875 43120f0d68cc01bd4a935d83c4fb1618 126 SUPERFAMILY SSF46785 23 123 3.6E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS20900 95ebb636eb9fd0b3ecdc841169b3dd57 94 TIGRFAM TIGR00302 TIGR00302: phosphoribosylformylglycinamidine synthase, purS protein 4 80 1.9E-20 T 29-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 SMALA_RS20900 95ebb636eb9fd0b3ecdc841169b3dd57 94 Gene3D G3DSA:3.30.1280.10 1 80 3.2E-29 T 29-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 SMALA_RS20900 95ebb636eb9fd0b3ecdc841169b3dd57 94 Hamap MF_01926 Phosphoribosylformylglycinamidine synthase subunit PurS [purS]. 2 79 21.828 T 29-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 SMALA_RS20900 95ebb636eb9fd0b3ecdc841169b3dd57 94 ProDom PD010362 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE PURS SYNTHETASE SYNTHASE COMPONENT SYNTHASE LIGASE FGAM UPF0062 I 10 76 5.0E-30 T 29-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 SMALA_RS20900 95ebb636eb9fd0b3ecdc841169b3dd57 94 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 4 79 3.5E-28 T 29-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 SMALA_RS20900 95ebb636eb9fd0b3ecdc841169b3dd57 94 SUPERFAMILY SSF82697 3 78 3.84E-25 T 29-03-2018 SMALA_RS17620 88e0ac5b414fed35ea47679b604f8f74 240 SUPERFAMILY SSF46894 174 228 1.02E-6 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS17620 88e0ac5b414fed35ea47679b604f8f74 240 Gene3D G3DSA:1.10.10.10 69 226 4.9E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS01920 9c4db9e7a1d6911c2936071762d2300a 324 Pfam PF03781 Sulfatase-modifying factor enzyme 1 44 322 4.5E-86 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 SMALA_RS01920 9c4db9e7a1d6911c2936071762d2300a 324 Gene3D G3DSA:3.90.1580.10 28 324 3.8E-100 T 29-03-2018 SMALA_RS01920 9c4db9e7a1d6911c2936071762d2300a 324 SUPERFAMILY SSF56436 44 324 6.04E-96 T 29-03-2018 IPR016187 C-type lectin fold SMALA_RS29715 b422da0d9225af6b52cba496db75ddd8 119 SUPERFAMILY SSF46785 6 80 2.1E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS29715 b422da0d9225af6b52cba496db75ddd8 119 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 76 1.3E-15 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS29715 b422da0d9225af6b52cba496db75ddd8 119 Gene3D G3DSA:1.10.10.10 2 78 7.7E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS29715 b422da0d9225af6b52cba496db75ddd8 119 SMART SM00345 17 76 2.6E-13 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS30425 e7fd19a517303f64d68548995cc80d5a 386 Pfam PF10935 Protein of unknown function (DUF2637) 60 219 2.1E-24 T 29-03-2018 IPR021235 Protein of unknown function DUF2637 SMALA_RS12455 7571319929661bdb18682be7a274cae7 431 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 363 372 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMALA_RS12455 7571319929661bdb18682be7a274cae7 431 Gene3D G3DSA:1.10.630.10 4 423 7.9E-77 T 29-03-2018 SMALA_RS12455 7571319929661bdb18682be7a274cae7 431 SUPERFAMILY SSF48264 24 424 1.11E-90 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS12455 7571319929661bdb18682be7a274cae7 431 Pfam PF00067 Cytochrome P450 295 391 7.5E-18 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS12455 7571319929661bdb18682be7a274cae7 431 PRINTS PR00359 B-class P450 signature 170 185 3.4E-35 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS12455 7571319929661bdb18682be7a274cae7 431 PRINTS PR00359 B-class P450 signature 153 169 3.4E-35 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS12455 7571319929661bdb18682be7a274cae7 431 PRINTS PR00359 B-class P450 signature 361 370 3.4E-35 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS12455 7571319929661bdb18682be7a274cae7 431 PRINTS PR00359 B-class P450 signature 294 305 3.4E-35 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS12455 7571319929661bdb18682be7a274cae7 431 PRINTS PR00359 B-class P450 signature 312 339 3.4E-35 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS12455 7571319929661bdb18682be7a274cae7 431 PRINTS PR00359 B-class P450 signature 101 112 3.4E-35 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS12455 7571319929661bdb18682be7a274cae7 431 PRINTS PR00359 B-class P450 signature 207 229 3.4E-35 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS12455 7571319929661bdb18682be7a274cae7 431 PRINTS PR00359 B-class P450 signature 370 381 3.4E-35 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS31760 f223b925f26e8b99d52c985f8b8ba67e 126 ProSitePatterns PS00234 Gas vesicles protein GVPa signature 1. 20 34 - T 29-03-2018 IPR018493 Gas vesicle protein GvpA, conserved site GO:0005198|GO:0012506 SMALA_RS31760 f223b925f26e8b99d52c985f8b8ba67e 126 ProSitePatterns PS00669 Gas vesicles protein GVPa signature 2. 53 66 - T 29-03-2018 IPR018493 Gas vesicle protein GvpA, conserved site GO:0005198|GO:0012506 SMALA_RS31760 f223b925f26e8b99d52c985f8b8ba67e 126 Pfam PF00741 Gas vesicle protein 19 57 3.3E-12 T 29-03-2018 IPR000638 Gas vesicle protein GvpA GO:0005198|GO:0012506 SMALA_RS31760 f223b925f26e8b99d52c985f8b8ba67e 126 Hamap MF_00576 Gas vesicle structural protein [gvpA]. 8 96 26.97 T 29-03-2018 IPR000638 Gas vesicle protein GvpA GO:0005198|GO:0012506 SMALA_RS25965 a52abb2fe01db071f445ad27ceb26c93 255 Pfam PF12138 Spherulation-specific family 4 24 247 2.6E-16 T 29-03-2018 IPR021986 Spherulation-specific family 4 SMALA_RS12160 805d3b3712b328f3954d30f89802cf5f 295 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 17 264 6.6E-76 T 29-03-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region SMALA_RS12160 805d3b3712b328f3954d30f89802cf5f 295 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 18 35 3.0E-43 T 29-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) SMALA_RS12160 805d3b3712b328f3954d30f89802cf5f 295 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 91 112 3.0E-43 T 29-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) SMALA_RS12160 805d3b3712b328f3954d30f89802cf5f 295 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 155 175 3.0E-43 T 29-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) SMALA_RS12160 805d3b3712b328f3954d30f89802cf5f 295 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 203 220 3.0E-43 T 29-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) SMALA_RS12160 805d3b3712b328f3954d30f89802cf5f 295 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 245 263 3.0E-43 T 29-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) SMALA_RS12160 805d3b3712b328f3954d30f89802cf5f 295 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 132 154 3.0E-43 T 29-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) SMALA_RS12160 805d3b3712b328f3954d30f89802cf5f 295 Gene3D G3DSA:2.120.10.30 6 295 3.0E-34 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like SMALA_RS12160 805d3b3712b328f3954d30f89802cf5f 295 SUPERFAMILY SSF63829 10 292 2.55E-60 T 29-03-2018 SMALA_RS21175 db8d3a2561f29be594fb804526bfb149 173 TIGRFAM TIGR00632 vsr: DNA mismatch endonuclease Vsr 42 151 1.7E-32 T 29-03-2018 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 SMALA_RS21175 db8d3a2561f29be594fb804526bfb149 173 Gene3D G3DSA:3.40.960.10 52 172 2.3E-27 T 29-03-2018 SMALA_RS21175 db8d3a2561f29be594fb804526bfb149 173 SUPERFAMILY SSF52980 38 159 9.12E-38 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 SMALA_RS21175 db8d3a2561f29be594fb804526bfb149 173 Pfam PF03852 DNA mismatch endonuclease Vsr 42 104 3.4E-17 T 29-03-2018 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 SMALA_RS04700 2b547059e157d2e396af418a40044119 819 Gene3D G3DSA:2.60.120.260 663 819 2.6E-26 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS04700 2b547059e157d2e396af418a40044119 819 Pfam PF07995 Glucose / Sorbosone dehydrogenase 61 333 2.3E-33 T 29-03-2018 IPR012938 Glucose/Sorbosone dehydrogenase SMALA_RS04700 2b547059e157d2e396af418a40044119 819 SUPERFAMILY SSF49299 495 581 4.97E-24 T 29-03-2018 IPR000601 PKD domain SMALA_RS04700 2b547059e157d2e396af418a40044119 819 Pfam PF03422 Carbohydrate binding module (family 6) 693 817 1.9E-31 T 29-03-2018 IPR005084 Carbohydrate binding module family 6 GO:0030246 SMALA_RS04700 2b547059e157d2e396af418a40044119 819 SMART SM00089 498 581 5.1E-24 T 29-03-2018 IPR022409 PKD/Chitinase domain SMALA_RS04700 2b547059e157d2e396af418a40044119 819 Gene3D G3DSA:2.120.10.30 31 491 5.1E-83 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like SMALA_RS04700 2b547059e157d2e396af418a40044119 819 SMART SM00606 685 818 8.7E-43 T 29-03-2018 IPR006584 Cellulose binding, type IV GO:0030246 SMALA_RS04700 2b547059e157d2e396af418a40044119 819 Pfam PF00801 PKD domain 513 568 9.4E-15 T 29-03-2018 IPR000601 PKD domain SMALA_RS04700 2b547059e157d2e396af418a40044119 819 Gene3D G3DSA:2.60.40.10 492 580 4.0E-25 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS04700 2b547059e157d2e396af418a40044119 819 SUPERFAMILY SSF49785 687 817 1.02E-27 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS04700 2b547059e157d2e396af418a40044119 819 SUPERFAMILY SSF50952 396 475 7.59E-24 T 29-03-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 SMALA_RS04700 2b547059e157d2e396af418a40044119 819 SUPERFAMILY SSF50952 48 366 7.59E-24 T 29-03-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 SMALA_RS03600 22cf202298bc86cf6e55107dc283eeb9 1214 Gene3D G3DSA:3.30.420.40 267 671 0.42 T 29-03-2018 SMALA_RS03600 22cf202298bc86cf6e55107dc283eeb9 1214 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 7 185 3.5E-57 T 29-03-2018 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403 SMALA_RS03600 22cf202298bc86cf6e55107dc283eeb9 1214 Pfam PF02538 Hydantoinase B/oxoprolinase 691 1197 6.7E-200 T 29-03-2018 IPR003692 Hydantoinase B/oxoprolinase GO:0003824 Reactome: R-HSA-174403 SMALA_RS03600 22cf202298bc86cf6e55107dc283eeb9 1214 Pfam PF01968 Hydantoinase/oxoprolinase 205 492 7.4E-111 T 29-03-2018 IPR002821 Hydantoinase/oxoprolinase GO:0016787 Reactome: R-HSA-174403 SMALA_RS24830 150aa5a7747089381f150fe3531440a4 215 SUPERFAMILY SSF48498 87 212 2.31E-34 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS24830 150aa5a7747089381f150fe3531440a4 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 6.3E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS24830 150aa5a7747089381f150fe3531440a4 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 6.3E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS24830 150aa5a7747089381f150fe3531440a4 215 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 65 9.3E-14 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS24830 150aa5a7747089381f150fe3531440a4 215 Gene3D G3DSA:1.10.10.60 1 67 1.4E-17 T 29-03-2018 SMALA_RS24830 150aa5a7747089381f150fe3531440a4 215 SUPERFAMILY SSF46689 9 91 3.28E-18 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS24830 150aa5a7747089381f150fe3531440a4 215 Gene3D G3DSA:1.10.357.10 68 214 2.0E-26 T 29-03-2018 SMALA_RS02795 22807644ae47c0c5e0e20d24217ae27d 125 Gene3D G3DSA:2.30.110.10 5 125 1.1E-9 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS02795 22807644ae47c0c5e0e20d24217ae27d 125 Pfam PF10012 Uncharacterized protein conserved in bacteria (DUF2255) 8 122 2.7E-43 T 29-03-2018 IPR016888 Uncharacterised conserved protein UCP028498 SMALA_RS41940 689e055fa84863f476f67367928da2aa 409 SUPERFAMILY SSF51905 8 229 3.11E-48 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS41940 689e055fa84863f476f67367928da2aa 409 SUPERFAMILY SSF51905 332 396 3.11E-48 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS41940 689e055fa84863f476f67367928da2aa 409 Gene3D G3DSA:3.50.50.60 6 409 4.3E-44 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS41940 689e055fa84863f476f67367928da2aa 409 Pfam PF01266 FAD dependent oxidoreductase 9 371 1.4E-48 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 SMALA_RS33745 d07fc5aba9db2b6b407ef8a54fb2d7bb 543 Gene3D G3DSA:3.40.50.300 279 483 3.4E-10 T 29-03-2018 SMALA_RS33745 d07fc5aba9db2b6b407ef8a54fb2d7bb 543 SUPERFAMILY SSF52540 285 511 4.03E-15 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS13355 5f9ca2bbc6242033e97eced28403a87b 340 Gene3D G3DSA:3.40.960.10 223 335 6.5E-5 T 29-03-2018 SMALA_RS04310 16a79c6c72d70c3d95c7a392b57cd5f3 417 SUPERFAMILY SSF103473 10 393 4.97E-40 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS04310 16a79c6c72d70c3d95c7a392b57cd5f3 417 Pfam PF07690 Major Facilitator Superfamily 19 362 6.6E-29 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS04310 16a79c6c72d70c3d95c7a392b57cd5f3 417 Gene3D G3DSA:1.20.1250.20 198 405 2.6E-11 T 29-03-2018 SMALA_RS04310 16a79c6c72d70c3d95c7a392b57cd5f3 417 Gene3D G3DSA:1.20.1250.20 5 197 9.5E-24 T 29-03-2018 SMALA_RS37710 85aee05cc84c573eacf5411f2a2ebc55 151 Pfam PF06841 T4-like virus tail tube protein gp19 13 148 7.2E-36 T 29-03-2018 IPR010667 Bacteriophage T4, Gp19, tail tube GO:0005198 SMALA_RS37710 85aee05cc84c573eacf5411f2a2ebc55 151 TIGRFAM TIGR02241 TIGR02241: conserved hypothetical phage tail region protein 8 150 7.7E-33 T 29-03-2018 IPR011747 Conserved hypothetical protein CHP02241 SMALA_RS20235 fcf89f89051b746f96a06624d97b4b68 424 SUPERFAMILY SSF48264 23 420 1.19E-53 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS20235 fcf89f89051b746f96a06624d97b4b68 424 Gene3D G3DSA:1.10.630.10 29 420 2.4E-39 T 29-03-2018 SMALA_RS20235 fcf89f89051b746f96a06624d97b4b68 424 PRINTS PR00359 B-class P450 signature 356 365 3.9E-14 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS20235 fcf89f89051b746f96a06624d97b4b68 424 PRINTS PR00359 B-class P450 signature 309 336 3.9E-14 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS20235 fcf89f89051b746f96a06624d97b4b68 424 PRINTS PR00359 B-class P450 signature 163 179 3.9E-14 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS33220 cb66d1b2f21168f73d323769c6e0410c 251 Pfam PF10935 Protein of unknown function (DUF2637) 119 228 2.6E-8 T 29-03-2018 IPR021235 Protein of unknown function DUF2637 SMALA_RS13475 30b34af950ebe6c42a0fb45e6b5cad86 454 Gene3D G3DSA:3.60.40.10 184 444 1.2E-31 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS13475 30b34af950ebe6c42a0fb45e6b5cad86 454 SMART SM00331 190 444 3.1E-4 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS13475 30b34af950ebe6c42a0fb45e6b5cad86 454 Pfam PF13672 Protein phosphatase 2C 198 407 2.7E-14 T 29-03-2018 SMALA_RS13475 30b34af950ebe6c42a0fb45e6b5cad86 454 SMART SM00332 180 442 6.9E-9 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS13475 30b34af950ebe6c42a0fb45e6b5cad86 454 SUPERFAMILY SSF81606 186 444 6.28E-40 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS19305 5f61e961aaebdc0375225f102e6fcd51 711 Pfam PF05425 Copper resistance protein D 359 438 2.3E-19 T 29-03-2018 IPR008457 Copper resistance protein D GO:0016021 SMALA_RS19305 5f61e961aaebdc0375225f102e6fcd51 711 Gene3D G3DSA:2.60.40.1220 50 148 3.3E-29 T 29-03-2018 SMALA_RS19305 5f61e961aaebdc0375225f102e6fcd51 711 Pfam PF04234 CopC domain 51 147 1.6E-24 T 29-03-2018 IPR007348 CopC domain GO:0005507|GO:0042597|GO:0046688 SMALA_RS19305 5f61e961aaebdc0375225f102e6fcd51 711 SUPERFAMILY SSF81296 50 147 3.15E-25 T 29-03-2018 IPR014756 Immunoglobulin E-set SMALA_RS03285 fe7a815088dbaa287c55a904d7915122 227 Pfam PF03551 Transcriptional regulator PadR-like family 70 138 1.6E-21 T 29-03-2018 IPR005149 Transcription regulator PadR, N-terminal SMALA_RS03285 fe7a815088dbaa287c55a904d7915122 227 SUPERFAMILY SSF46785 55 148 2.73E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS03285 fe7a815088dbaa287c55a904d7915122 227 Gene3D G3DSA:1.10.10.10 54 163 1.9E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS27595 9386eaf99f8d5a529af4410e22a435d6 445 SUPERFAMILY SSF50998 70 194 2.31E-6 T 29-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily SMALA_RS27595 9386eaf99f8d5a529af4410e22a435d6 445 SUPERFAMILY SSF50998 290 408 2.31E-6 T 29-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily SMALA_RS27595 9386eaf99f8d5a529af4410e22a435d6 445 Pfam PF13360 PQQ-like domain 59 179 2.0E-5 T 29-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat SMALA_RS37265 47bd006404bb556c58d404845046327f 506 Pfam PF13520 Amino acid permease 36 471 3.0E-60 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMALA_RS37265 47bd006404bb556c58d404845046327f 506 ProSitePatterns PS00218 Amino acid permeases signature. 63 94 - T 29-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 SMALA_RS37265 47bd006404bb556c58d404845046327f 506 PIRSF PIRSF006060 13 503 5.6E-63 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMALA_RS12600 6b25f01a756d271ce8462e05418f372b 226 Gene3D G3DSA:1.10.10.10 116 226 5.2E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS12600 6b25f01a756d271ce8462e05418f372b 226 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 219 2.8E-20 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS12600 6b25f01a756d271ce8462e05418f372b 226 SUPERFAMILY SSF52172 1 132 5.12E-38 T 29-03-2018 IPR011006 CheY-like superfamily SMALA_RS12600 6b25f01a756d271ce8462e05418f372b 226 Gene3D G3DSA:3.40.50.2300 1 115 1.4E-33 T 29-03-2018 SMALA_RS12600 6b25f01a756d271ce8462e05418f372b 226 Pfam PF00072 Response regulator receiver domain 3 112 3.7E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS12600 6b25f01a756d271ce8462e05418f372b 226 SMART SM00448 1 112 2.2E-37 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMALA_RS12600 6b25f01a756d271ce8462e05418f372b 226 SUPERFAMILY SSF46894 119 220 3.97E-24 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS12600 6b25f01a756d271ce8462e05418f372b 226 SMART SM00862 145 219 9.4E-22 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS04430 755639c77355bf021011b9fb4c9fb09d 208 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 64 3.2E-17 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS04430 755639c77355bf021011b9fb4c9fb09d 208 Gene3D G3DSA:1.10.357.10 2 187 4.8E-29 T 29-03-2018 SMALA_RS04430 755639c77355bf021011b9fb4c9fb09d 208 ProSitePatterns PS01081 TetR-type HTH domain signature. 32 63 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site SMALA_RS04430 755639c77355bf021011b9fb4c9fb09d 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 4.7E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS04430 755639c77355bf021011b9fb4c9fb09d 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 4.7E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS04430 755639c77355bf021011b9fb4c9fb09d 208 SUPERFAMILY SSF46689 13 77 2.0E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS15440 a0a129dc864fe88456d3b34b5c99e79b 304 Gene3D G3DSA:1.10.3720.10 16 304 2.6E-51 T 29-03-2018 SMALA_RS15440 a0a129dc864fe88456d3b34b5c99e79b 304 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 104 301 3.7E-18 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS15440 a0a129dc864fe88456d3b34b5c99e79b 304 SUPERFAMILY SSF161098 58 292 1.2E-56 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS24295 2887f9c163b8aa4945923770fa77133d 505 Gene3D G3DSA:2.160.20.80 77 323 6.5E-8 T 29-03-2018 SMALA_RS12080 5fc88a399bf9b9d0c4bf95e89be82581 325 SMART SM00418 251 322 7.8E-4 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS12080 5fc88a399bf9b9d0c4bf95e89be82581 325 SUPERFAMILY SSF46785 252 318 5.71E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS12080 5fc88a399bf9b9d0c4bf95e89be82581 325 Gene3D G3DSA:1.10.10.10 84 325 5.5E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS12080 5fc88a399bf9b9d0c4bf95e89be82581 325 Pfam PF01022 Bacterial regulatory protein, arsR family 261 298 5.1E-5 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS08520 bd310774be9e3c9227ebb54d06a8a1dc 311 SMART SM00244 22 180 2.3E-61 T 29-03-2018 IPR001107 Band 7 domain SMALA_RS08520 bd310774be9e3c9227ebb54d06a8a1dc 311 SUPERFAMILY SSF117892 55 187 1.27E-40 T 29-03-2018 IPR001107 Band 7 domain SMALA_RS08520 bd310774be9e3c9227ebb54d06a8a1dc 311 Pfam PF01145 SPFH domain / Band 7 family 26 196 2.6E-33 T 29-03-2018 IPR001107 Band 7 domain SMALA_RS08520 bd310774be9e3c9227ebb54d06a8a1dc 311 PRINTS PR00721 Stomatin signature 200 223 1.1E-60 T 29-03-2018 IPR001972 Stomatin family GO:0016020 SMALA_RS08520 bd310774be9e3c9227ebb54d06a8a1dc 311 PRINTS PR00721 Stomatin signature 112 129 1.1E-60 T 29-03-2018 IPR001972 Stomatin family GO:0016020 SMALA_RS08520 bd310774be9e3c9227ebb54d06a8a1dc 311 PRINTS PR00721 Stomatin signature 175 196 1.1E-60 T 29-03-2018 IPR001972 Stomatin family GO:0016020 SMALA_RS08520 bd310774be9e3c9227ebb54d06a8a1dc 311 PRINTS PR00721 Stomatin signature 29 51 1.1E-60 T 29-03-2018 IPR001972 Stomatin family GO:0016020 SMALA_RS08520 bd310774be9e3c9227ebb54d06a8a1dc 311 PRINTS PR00721 Stomatin signature 156 174 1.1E-60 T 29-03-2018 IPR001972 Stomatin family GO:0016020 SMALA_RS08520 bd310774be9e3c9227ebb54d06a8a1dc 311 PRINTS PR00721 Stomatin signature 77 98 1.1E-60 T 29-03-2018 IPR001972 Stomatin family GO:0016020 SMALA_RS08520 bd310774be9e3c9227ebb54d06a8a1dc 311 PRINTS PR00721 Stomatin signature 132 155 1.1E-60 T 29-03-2018 IPR001972 Stomatin family GO:0016020 SMALA_RS20280 ac638153eacabf5ad6343e258a93c762 241 Gene3D G3DSA:1.20.1260.10 49 238 1.9E-50 T 29-03-2018 IPR012347 Ferritin-related SMALA_RS20280 ac638153eacabf5ad6343e258a93c762 241 Pfam PF03713 Domain of unknown function (DUF305) 58 234 1.1E-41 T 29-03-2018 IPR005183 Domain of unknown function DUF305 SMALA_RS10545 151256afe24e03eaf5b847c39a5001bf 415 Gene3D G3DSA:2.60.40.10 38 135 9.0E-4 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS10545 151256afe24e03eaf5b847c39a5001bf 415 Gene3D G3DSA:2.40.440.10 246 366 2.1E-21 T 29-03-2018 SMALA_RS10545 151256afe24e03eaf5b847c39a5001bf 415 SUPERFAMILY SSF141523 244 365 1.57E-25 T 29-03-2018 SMALA_RS10545 151256afe24e03eaf5b847c39a5001bf 415 Pfam PF03734 L,D-transpeptidase catalytic domain 250 365 4.4E-12 T 29-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 SMALA_RS03820 ef8fce522399828f11ec34799e0fc75d 159 SUPERFAMILY SSF55811 10 136 5.15E-33 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMALA_RS03820 ef8fce522399828f11ec34799e0fc75d 159 Gene3D G3DSA:3.90.79.10 1 147 2.0E-29 T 29-03-2018 SMALA_RS03820 ef8fce522399828f11ec34799e0fc75d 159 Pfam PF00293 NUDIX domain 21 135 5.2E-21 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SMALA_RS17285 6d33cf2a30522afbaa73e9da72874a45 372 TIGRFAM TIGR01366 serC_3: putative phosphoserine aminotransferase 11 371 2.9E-212 T 29-03-2018 IPR006272 Phosphoserine aminotransferase, Mycobacterial-type GO:0004648|GO:0006564|GO:0009058 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52 SMALA_RS17285 6d33cf2a30522afbaa73e9da72874a45 372 Pfam PF00266 Aminotransferase class-V 27 331 1.7E-19 T 29-03-2018 IPR000192 Aminotransferase class V domain SMALA_RS17285 6d33cf2a30522afbaa73e9da72874a45 372 SUPERFAMILY SSF53383 12 370 4.59E-79 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS17285 6d33cf2a30522afbaa73e9da72874a45 372 Gene3D G3DSA:3.90.1150.10 261 372 1.7E-22 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS17285 6d33cf2a30522afbaa73e9da72874a45 372 Hamap MF_00160 Phosphoserine aminotransferase [serC]. 5 372 23.87 T 29-03-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 SMALA_RS17285 6d33cf2a30522afbaa73e9da72874a45 372 PIRSF PIRSF000525 2 372 2.4E-77 T 29-03-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 SMALA_RS17285 6d33cf2a30522afbaa73e9da72874a45 372 Gene3D G3DSA:3.40.640.10 21 260 1.2E-26 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS23745 95962d44bd097a940a89678f96413160 199 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 7 188 1.6E-38 T 29-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase SMALA_RS23745 95962d44bd097a940a89678f96413160 199 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 7 188 7.1E-43 T 29-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase SMALA_RS23745 95962d44bd097a940a89678f96413160 199 Gene3D G3DSA:3.40.50.10420 1 197 1.3E-57 T 29-03-2018 SMALA_RS23745 95962d44bd097a940a89678f96413160 199 SUPERFAMILY SSF100950 6 196 7.12E-44 T 29-03-2018 SMALA_RS23745 95962d44bd097a940a89678f96413160 199 PIRSF PIRSF006806 2 191 2.4E-31 T 29-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase SMALA_RS41170 b3379021adc962fae6aba251c62a1ff3 260 SMART SM00382 32 215 4.6E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS41170 b3379021adc962fae6aba251c62a1ff3 260 Pfam PF00005 ABC transporter 24 171 2.3E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS41170 b3379021adc962fae6aba251c62a1ff3 260 Gene3D G3DSA:3.40.50.300 5 244 2.5E-59 T 29-03-2018 SMALA_RS41170 b3379021adc962fae6aba251c62a1ff3 260 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS41170 b3379021adc962fae6aba251c62a1ff3 260 SUPERFAMILY SSF52540 17 223 2.45E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS34870 50699442be7ace1c68aea204bac19039 245 Gene3D G3DSA:3.40.50.880 11 220 1.1E-16 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS34870 50699442be7ace1c68aea204bac19039 245 SUPERFAMILY SSF52317 26 217 2.78E-18 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS34870 50699442be7ace1c68aea204bac19039 245 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 10 205 7.0E-35 T 29-03-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 SMALA_RS02475 4858af075d31eef2968a724d243301be 371 Gene3D G3DSA:3.40.50.720 21 367 1.3E-55 T 29-03-2018 SMALA_RS02475 4858af075d31eef2968a724d243301be 371 Pfam PF01370 NAD dependent epimerase/dehydratase family 31 271 4.0E-28 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 SMALA_RS02475 4858af075d31eef2968a724d243301be 371 SUPERFAMILY SSF51735 28 363 6.25E-66 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS32890 36a62c5eaad1619acef7c707e0043329 186 Gene3D G3DSA:1.20.1440.20 14 176 5.6E-38 T 29-03-2018 SMALA_RS32890 36a62c5eaad1619acef7c707e0043329 186 SUPERFAMILY SSF140478 26 140 2.09E-5 T 29-03-2018 IPR023353 LemA-like domain SMALA_RS03335 8ba1f54fc90eaf72dd1d5201e451ac72 157 Pfam PF02577 Bifunctional nuclease 6 128 2.3E-45 T 29-03-2018 IPR003729 Bifunctional nuclease domain GO:0004518 SMALA_RS03335 8ba1f54fc90eaf72dd1d5201e451ac72 157 SUPERFAMILY SSF103256 3 136 2.22E-46 T 29-03-2018 IPR003729 Bifunctional nuclease domain GO:0004518 SMALA_RS05260 bbcd1a403205db375750b4f99e7f89c0 409 Pfam PF07470 Glycosyl Hydrolase Family 88 76 360 7.3E-26 T 29-03-2018 IPR010905 Glycosyl hydrolase, family 88 SMALA_RS05260 bbcd1a403205db375750b4f99e7f89c0 409 SUPERFAMILY SSF48208 68 397 6.33E-102 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 SMALA_RS05260 bbcd1a403205db375750b4f99e7f89c0 409 Gene3D G3DSA:1.50.10.10 34 406 6.2E-98 T 29-03-2018 SMALA_RS27640 e688b9ee9804e8414d2fd4b2578c1cf3 317 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 3 310 6.5E-12 T 29-03-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 SMALA_RS27640 e688b9ee9804e8414d2fd4b2578c1cf3 317 Gene3D G3DSA:3.20.20.210 35 317 1.2E-55 T 29-03-2018 SMALA_RS27640 e688b9ee9804e8414d2fd4b2578c1cf3 317 SUPERFAMILY SSF51726 41 313 6.54E-30 T 29-03-2018 SMALA_RS37960 4a7202be06f2020d16cdba700fcf3f6f 211 Pfam PF00440 Bacterial regulatory proteins, tetR family 42 72 5.6E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS37960 4a7202be06f2020d16cdba700fcf3f6f 211 SUPERFAMILY SSF48498 93 196 3.24E-10 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS37960 4a7202be06f2020d16cdba700fcf3f6f 211 SUPERFAMILY SSF46689 18 88 2.0E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS37960 4a7202be06f2020d16cdba700fcf3f6f 211 Gene3D G3DSA:1.10.357.10 9 201 1.5E-29 T 29-03-2018 SMALA_RS42545 c049cdf8704ecf2169e54fc210f3cfff 406 Pfam PF07690 Major Facilitator Superfamily 42 255 1.5E-17 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS42545 c049cdf8704ecf2169e54fc210f3cfff 406 SUPERFAMILY SSF103473 15 402 8.89E-43 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS42545 c049cdf8704ecf2169e54fc210f3cfff 406 Gene3D G3DSA:1.20.1250.20 17 215 1.6E-18 T 29-03-2018 SMALA_RS42545 c049cdf8704ecf2169e54fc210f3cfff 406 Gene3D G3DSA:1.20.1250.20 218 405 2.0E-15 T 29-03-2018 SMALA_RS18130 981aae178c316f630c8cc717d4de47c2 380 SUPERFAMILY SSF55486 9 374 1.98E-104 T 29-03-2018 SMALA_RS18130 981aae178c316f630c8cc717d4de47c2 380 TIGRFAM TIGR03624 TIGR03624: putative hydrolase 10 375 1.5E-121 T 29-03-2018 IPR018766 Zinicin-like metallopeptidase type 2 SMALA_RS18130 981aae178c316f630c8cc717d4de47c2 380 Pfam PF10103 Zincin-like metallopeptidase 10 371 4.2E-121 T 29-03-2018 IPR018766 Zinicin-like metallopeptidase type 2 SMALA_RS18130 981aae178c316f630c8cc717d4de47c2 380 TIGRFAM TIGR03883 DUF2342_F420: uncharacterized protein, coenzyme F420 biosynthesis associated 10 375 4.3E-140 T 29-03-2018 IPR022454 Conserved hypothetical protein CHP03883, F420 biosynthesis associated SMALA_RS30180 6a2eacf1679ee71438a88a71a57ad7f0 428 SUPERFAMILY SSF53850 40 417 8.46E-58 T 29-03-2018 SMALA_RS30180 6a2eacf1679ee71438a88a71a57ad7f0 428 Gene3D G3DSA:3.40.190.10 16 194 1.5E-32 T 29-03-2018 SMALA_RS30180 6a2eacf1679ee71438a88a71a57ad7f0 428 Gene3D G3DSA:3.40.190.10 224 379 0.033 T 29-03-2018 SMALA_RS30180 6a2eacf1679ee71438a88a71a57ad7f0 428 Pfam PF01547 Bacterial extracellular solute-binding protein 48 333 2.2E-34 T 29-03-2018 IPR006059 Solute-binding family 1 GO:0006810 SMALA_RS23650 f3aee800a9c9050ad33b154c342e04eb 166 Pfam PF01047 MarR family 63 103 1.1E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS23650 f3aee800a9c9050ad33b154c342e04eb 166 Gene3D G3DSA:1.10.10.10 2 161 2.0E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS23650 f3aee800a9c9050ad33b154c342e04eb 166 SUPERFAMILY SSF46785 10 155 3.06E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS23650 f3aee800a9c9050ad33b154c342e04eb 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 64 80 3.2E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS23650 f3aee800a9c9050ad33b154c342e04eb 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 131 151 3.2E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS23650 f3aee800a9c9050ad33b154c342e04eb 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 81 96 3.2E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS23650 f3aee800a9c9050ad33b154c342e04eb 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 100 116 3.2E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS23650 f3aee800a9c9050ad33b154c342e04eb 166 SMART SM00347 38 141 2.5E-12 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS13290 70b7345ff6567b9a33827a801f1189b9 490 PIRSF PIRSF006060 3 488 1.5E-75 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMALA_RS13290 70b7345ff6567b9a33827a801f1189b9 490 Pfam PF00324 Amino acid permease 32 445 2.2E-115 T 29-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 SMALA_RS13290 70b7345ff6567b9a33827a801f1189b9 490 ProSitePatterns PS00218 Amino acid permeases signature. 57 87 - T 29-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 SMALA_RS06070 7c6f96c7dd1bb869dbb63b76c0810000 311 Pfam PF13602 Zinc-binding dehydrogenase 203 308 6.9E-8 T 29-03-2018 SMALA_RS06070 7c6f96c7dd1bb869dbb63b76c0810000 311 SMART SM00829 10 308 1.2E-10 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMALA_RS06070 7c6f96c7dd1bb869dbb63b76c0810000 311 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 89 2.9E-9 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMALA_RS06070 7c6f96c7dd1bb869dbb63b76c0810000 311 SUPERFAMILY SSF50129 1 154 3.2E-37 T 29-03-2018 IPR011032 GroES-like SMALA_RS06070 7c6f96c7dd1bb869dbb63b76c0810000 311 Gene3D G3DSA:3.90.180.10 1 309 1.2E-58 T 29-03-2018 SMALA_RS06070 7c6f96c7dd1bb869dbb63b76c0810000 311 SUPERFAMILY SSF51735 118 242 1.28E-22 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS41660 7985f63dd1b1ae0225ee4ea8c37e9d4f 377 SUPERFAMILY SSF52266 46 240 2.26E-30 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain SMALA_RS41660 7985f63dd1b1ae0225ee4ea8c37e9d4f 377 Gene3D G3DSA:2.60.120.260 249 375 3.6E-20 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS41660 7985f63dd1b1ae0225ee4ea8c37e9d4f 377 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 54 229 3.2E-19 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain SMALA_RS41660 7985f63dd1b1ae0225ee4ea8c37e9d4f 377 Gene3D G3DSA:3.40.50.1110 44 248 2.0E-33 T 29-03-2018 SMALA_RS41660 7985f63dd1b1ae0225ee4ea8c37e9d4f 377 SUPERFAMILY SSF49785 245 368 1.65E-15 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS39995 7eae2d95ce9864bd790068e36565ae92 141 Gene3D G3DSA:3.10.450.50 1 130 4.2E-21 T 29-03-2018 SMALA_RS39995 7eae2d95ce9864bd790068e36565ae92 141 SUPERFAMILY SSF54427 9 125 2.66E-19 T 29-03-2018 IPR032710 NTF2-like domain SMALA_RS39995 7eae2d95ce9864bd790068e36565ae92 141 Pfam PF12680 SnoaL-like domain 13 117 8.2E-12 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain SMALA_RS14850 fd81954aca9fca6e91ce51a93170f762 226 Pfam PF07729 FCD domain 93 213 1.0E-26 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS14850 fd81954aca9fca6e91ce51a93170f762 226 SMART SM00345 5 64 2.5E-21 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS14850 fd81954aca9fca6e91ce51a93170f762 226 SUPERFAMILY SSF46785 4 80 4.97E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS14850 fd81954aca9fca6e91ce51a93170f762 226 Gene3D G3DSA:1.10.10.10 1 66 4.0E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS14850 fd81954aca9fca6e91ce51a93170f762 226 SUPERFAMILY SSF48008 89 222 6.02E-26 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS14850 fd81954aca9fca6e91ce51a93170f762 226 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 38 54 6.4E-10 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS14850 fd81954aca9fca6e91ce51a93170f762 226 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 24 38 6.4E-10 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS14850 fd81954aca9fca6e91ce51a93170f762 226 SMART SM00895 93 215 6.9E-18 T 29-03-2018 IPR011711 GntR, C-terminal SMALA_RS14850 fd81954aca9fca6e91ce51a93170f762 226 Gene3D G3DSA:1.20.120.530 79 226 9.2E-29 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SMALA_RS14850 fd81954aca9fca6e91ce51a93170f762 226 Pfam PF00392 Bacterial regulatory proteins, gntR family 3 64 1.1E-19 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS32035 2be802d5cfd11ec4f05ed3b1666b4f30 328 Gene3D G3DSA:3.40.50.720 1 170 1.0E-29 T 29-03-2018 SMALA_RS32035 2be802d5cfd11ec4f05ed3b1666b4f30 328 Gene3D G3DSA:3.90.25.10 171 327 9.0E-36 T 29-03-2018 SMALA_RS32035 2be802d5cfd11ec4f05ed3b1666b4f30 328 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 4 322 3.1E-94 T 29-03-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-70370 SMALA_RS32035 2be802d5cfd11ec4f05ed3b1666b4f30 328 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 250 5.4E-57 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 SMALA_RS32035 2be802d5cfd11ec4f05ed3b1666b4f30 328 SUPERFAMILY SSF51735 1 318 1.83E-87 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS24585 d5e771ac34d78deb4fc29e938220f606 280 Gene3D G3DSA:2.40.10.10 37 128 0.0014 T 29-03-2018 SMALA_RS24585 d5e771ac34d78deb4fc29e938220f606 280 Gene3D G3DSA:2.40.10.10 129 261 7.3E-17 T 29-03-2018 SMALA_RS24585 d5e771ac34d78deb4fc29e938220f606 280 Pfam PF13365 Trypsin-like peptidase domain 51 218 1.4E-12 T 29-03-2018 SMALA_RS24585 d5e771ac34d78deb4fc29e938220f606 280 SUPERFAMILY SSF50494 33 233 2.15E-15 T 29-03-2018 IPR009003 Peptidase S1, PA clan SMALA_RS04500 e77737054217cbb6f643a28ccafcbbe0 313 SUPERFAMILY SSF56601 43 295 1.61E-58 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMALA_RS04500 e77737054217cbb6f643a28ccafcbbe0 313 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 72 83 4.8E-15 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 SMALA_RS04500 e77737054217cbb6f643a28ccafcbbe0 313 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 159 172 4.8E-15 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 SMALA_RS04500 e77737054217cbb6f643a28ccafcbbe0 313 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 126 143 4.8E-15 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 SMALA_RS04500 e77737054217cbb6f643a28ccafcbbe0 313 Gene3D G3DSA:3.40.710.10 13 311 8.9E-52 T 29-03-2018 SMALA_RS04500 e77737054217cbb6f643a28ccafcbbe0 313 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 38 281 2.6E-44 T 29-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 SMALA_RS18435 4459947a40c7e289593b8f0d4ebc9c4c 433 Pfam PF04412 Protein of unknown function (DUF521) 3 415 1.2E-107 T 29-03-2018 IPR007506 Aconitase X catalytic domain, putative SMALA_RS34320 a4cce42087922775391df30fb1fcba7d 261 SUPERFAMILY SSF161098 2 261 8.78E-71 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS34320 a4cce42087922775391df30fb1fcba7d 261 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 255 7.4E-18 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS34320 a4cce42087922775391df30fb1fcba7d 261 Gene3D G3DSA:1.10.3720.10 1 249 1.3E-39 T 29-03-2018 SMALA_RS31650 8ddbc25941e8b1b586795fba9ed5dba2 210 SUPERFAMILY SSF51735 1 201 5.95E-28 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS31650 8ddbc25941e8b1b586795fba9ed5dba2 210 Pfam PF13460 NAD(P)H-binding 7 198 2.3E-22 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS31650 8ddbc25941e8b1b586795fba9ed5dba2 210 Gene3D G3DSA:3.40.50.720 1 210 1.5E-18 T 29-03-2018 SMALA_RS40005 2e74afff2c25b56b8a42ce2cddcdeafa 130 Pfam PF07366 SnoaL-like polyketide cyclase 10 128 1.4E-19 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain SMALA_RS40005 2e74afff2c25b56b8a42ce2cddcdeafa 130 Gene3D G3DSA:3.10.450.50 2 129 2.0E-18 T 29-03-2018 SMALA_RS40005 2e74afff2c25b56b8a42ce2cddcdeafa 130 SUPERFAMILY SSF54427 5 128 4.77E-26 T 29-03-2018 IPR032710 NTF2-like domain SMALA_RS13860 8cd456213a25ba4baf666c8d409918f2 498 Gene3D G3DSA:3.40.309.10 263 460 3.6E-62 T 29-03-2018 SMALA_RS13860 8cd456213a25ba4baf666c8d409918f2 498 Gene3D G3DSA:3.40.605.10 1 262 5.8E-89 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS13860 8cd456213a25ba4baf666c8d409918f2 498 SUPERFAMILY SSF53720 2 482 4.06E-148 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMALA_RS13860 8cd456213a25ba4baf666c8d409918f2 498 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 4 481 7.1E-242 T 29-03-2018 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00410+1.2.1.18|KEGG: 00562+1.2.1.18|KEGG: 00640+1.2.1.18+1.2.1.27|MetaCyc: PWY-5642|MetaCyc: PWY-6373|Reactome: R-HSA-70895 SMALA_RS13860 8cd456213a25ba4baf666c8d409918f2 498 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 274 285 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 SMALA_RS13860 8cd456213a25ba4baf666c8d409918f2 498 Pfam PF00171 Aldehyde dehydrogenase family 19 477 4.0E-139 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS13670 089e4fefdf9d5acb16e5cf06b53d0d44 199 Gene3D G3DSA:1.10.10.60 2 58 2.9E-12 T 29-03-2018 SMALA_RS13670 089e4fefdf9d5acb16e5cf06b53d0d44 199 SUPERFAMILY SSF46689 4 74 8.21E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS13670 089e4fefdf9d5acb16e5cf06b53d0d44 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 57 2.2E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS13670 089e4fefdf9d5acb16e5cf06b53d0d44 199 SUPERFAMILY SSF48498 81 188 1.11E-15 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS13670 089e4fefdf9d5acb16e5cf06b53d0d44 199 Gene3D G3DSA:1.10.357.10 59 189 8.2E-21 T 29-03-2018 SMALA_RS12765 fc21c65b8191200248a77270bffafc9b 192 SUPERFAMILY SSF46689 3 68 1.69E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS12765 fc21c65b8191200248a77270bffafc9b 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 56 5.4E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS12765 fc21c65b8191200248a77270bffafc9b 192 Gene3D G3DSA:1.10.357.10 6 192 2.0E-26 T 29-03-2018 SMALA_RS40475 7b4749e643b3d55bf8968be50231db83 398 SUPERFAMILY SSF90002 252 315 1.06E-11 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal SMALA_RS40475 7b4749e643b3d55bf8968be50231db83 398 SUPERFAMILY SSF90002 342 367 1.06E-11 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal SMALA_RS40475 7b4749e643b3d55bf8968be50231db83 398 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 253 367 2.0E-19 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal SMALA_RS40475 7b4749e643b3d55bf8968be50231db83 398 Gene3D G3DSA:3.30.1220.10 245 369 6.8E-21 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal SMALA_RS40475 7b4749e643b3d55bf8968be50231db83 398 SMART SM00833 252 368 4.6E-25 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal SMALA_RS09940 8f92ae00108e405b0e1a03d949e0f00a 243 Pfam PF01988 VIT family 28 235 8.0E-63 T 29-03-2018 IPR008217 Ccc1 family SMALA_RS31055 1430cd7b7909fb8c4914e3fbaf43e5f0 358 SUPERFAMILY SSF51126 30 349 2.15E-37 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor SMALA_RS31055 1430cd7b7909fb8c4914e3fbaf43e5f0 358 Gene3D G3DSA:2.160.20.10 38 356 3.6E-38 T 29-03-2018 IPR012334 Pectin lyase fold SMALA_RS31055 1430cd7b7909fb8c4914e3fbaf43e5f0 358 SMART SM00710 217 238 7.8 T 29-03-2018 IPR006626 Parallel beta-helix repeat SMALA_RS31055 1430cd7b7909fb8c4914e3fbaf43e5f0 358 SMART SM00710 162 184 66.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat SMALA_RS31055 1430cd7b7909fb8c4914e3fbaf43e5f0 358 SMART SM00710 281 308 490.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat SMALA_RS31055 1430cd7b7909fb8c4914e3fbaf43e5f0 358 SMART SM00710 245 280 3000.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat SMALA_RS31055 1430cd7b7909fb8c4914e3fbaf43e5f0 358 SMART SM00710 195 216 230.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat SMALA_RS31055 1430cd7b7909fb8c4914e3fbaf43e5f0 358 Pfam PF13229 Right handed beta helix region 103 254 2.4E-12 T 29-03-2018 SMALA_RS40730 aa7c5b842c07438fb21040975dc1ac2a 270 SUPERFAMILY SSF51735 7 255 8.92E-76 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS40730 aa7c5b842c07438fb21040975dc1ac2a 270 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 5.9E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40730 aa7c5b842c07438fb21040975dc1ac2a 270 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 5.9E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40730 aa7c5b842c07438fb21040975dc1ac2a 270 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 5.9E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40730 aa7c5b842c07438fb21040975dc1ac2a 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 2.2E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40730 aa7c5b842c07438fb21040975dc1ac2a 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 2.2E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40730 aa7c5b842c07438fb21040975dc1ac2a 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 2.2E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40730 aa7c5b842c07438fb21040975dc1ac2a 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 2.2E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40730 aa7c5b842c07438fb21040975dc1ac2a 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 2.2E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40730 aa7c5b842c07438fb21040975dc1ac2a 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 2.2E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40730 aa7c5b842c07438fb21040975dc1ac2a 270 Gene3D G3DSA:3.40.50.720 47 263 2.4E-55 T 29-03-2018 SMALA_RS40730 aa7c5b842c07438fb21040975dc1ac2a 270 Gene3D G3DSA:3.40.50.720 1 46 3.1E-9 T 29-03-2018 SMALA_RS40730 aa7c5b842c07438fb21040975dc1ac2a 270 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 254 1.0E-60 T 29-03-2018 SMALA_RS15175 a6bc5264c274fb7ececb9a25682dc35e 497 Gene3D G3DSA:1.20.1250.20 296 497 4.0E-13 T 29-03-2018 SMALA_RS15175 a6bc5264c274fb7ececb9a25682dc35e 497 SUPERFAMILY SSF103473 45 233 4.05E-24 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS15175 a6bc5264c274fb7ececb9a25682dc35e 497 Pfam PF07690 Major Facilitator Superfamily 61 347 3.2E-21 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS15175 a6bc5264c274fb7ececb9a25682dc35e 497 Gene3D G3DSA:1.20.1250.20 45 244 3.8E-23 T 29-03-2018 SMALA_RS15175 a6bc5264c274fb7ececb9a25682dc35e 497 SUPERFAMILY SSF103473 228 496 1.15E-16 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS10035 76d036107f0eebb05acd452a848dc595 688 Pfam PF01032 FecCD transport family 32 346 1.1E-67 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 SMALA_RS10035 76d036107f0eebb05acd452a848dc595 688 Pfam PF01032 FecCD transport family 381 685 3.5E-83 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 SMALA_RS10035 76d036107f0eebb05acd452a848dc595 688 SUPERFAMILY SSF81345 364 685 8.76E-73 T 29-03-2018 IPR029022 ABC transporter, BtuC-like SMALA_RS10035 76d036107f0eebb05acd452a848dc595 688 Gene3D G3DSA:1.10.3470.10 363 688 2.1E-60 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SMALA_RS10035 76d036107f0eebb05acd452a848dc595 688 Gene3D G3DSA:1.10.3470.10 16 354 9.3E-57 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SMALA_RS10035 76d036107f0eebb05acd452a848dc595 688 SUPERFAMILY SSF81345 22 346 5.49E-57 T 29-03-2018 IPR029022 ABC transporter, BtuC-like SMALA_RS34760 a42a08332d31dd82dc74adcc0854f46b 406 SUPERFAMILY SSF55073 13 190 4.55E-11 T 29-03-2018 IPR029787 Nucleotide cyclase SMALA_RS34760 a42a08332d31dd82dc74adcc0854f46b 406 Gene3D G3DSA:3.30.70.1230 12 263 3.5E-12 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 SMALA_RS29310 09d8c13993cd2c054f77d29b9622c891 316 Pfam PF02401 LytB protein 7 283 1.2E-81 T 29-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 SMALA_RS29310 09d8c13993cd2c054f77d29b9622c891 316 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 7 285 9.8E-87 T 29-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 SMALA_RS29310 09d8c13993cd2c054f77d29b9622c891 316 Gene3D G3DSA:3.40.50.1220 22 301 2.9E-4 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain SMALA_RS29310 09d8c13993cd2c054f77d29b9622c891 316 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 5 287 35.086 T 29-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 SMALA_RS13805 3b5be7ef18de5fbbde92682e422ac7ba 514 Pfam PF03703 Bacterial PH domain 77 156 8.1E-16 T 29-03-2018 IPR005182 Domain of unknown function DUF304 SMALA_RS13805 3b5be7ef18de5fbbde92682e422ac7ba 514 Pfam PF03703 Bacterial PH domain 421 479 8.8E-6 T 29-03-2018 IPR005182 Domain of unknown function DUF304 SMALA_RS13805 3b5be7ef18de5fbbde92682e422ac7ba 514 PIRSF PIRSF026631 24 499 2.1E-60 T 29-03-2018 IPR014529 Uncharacterised conserved protein UCP026631 SMALA_RS15150 31189bd8ef8881755e9f5f343b16a489 261 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 153 236 3.5E-6 T 29-03-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 SMALA_RS15150 31189bd8ef8881755e9f5f343b16a489 261 Gene3D G3DSA:3.30.230.10 43 259 5.9E-37 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SMALA_RS15150 31189bd8ef8881755e9f5f343b16a489 261 SUPERFAMILY SSF54211 117 249 6.83E-17 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SMALA_RS39490 eca78459582ba257acd1cc69c1852b34 315 SUPERFAMILY SSF50486 206 308 1.18E-18 T 29-03-2018 IPR011034 Formyl transferase, C-terminal-like GO:0003824 SMALA_RS39490 eca78459582ba257acd1cc69c1852b34 315 Pfam PF00551 Formyl transferase 1 169 1.0E-31 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SMALA_RS39490 eca78459582ba257acd1cc69c1852b34 315 Pfam PF02911 Formyl transferase, C-terminal domain 205 306 1.7E-16 T 29-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SMALA_RS39490 eca78459582ba257acd1cc69c1852b34 315 Gene3D G3DSA:3.10.25.10 205 312 1.8E-21 T 29-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SMALA_RS39490 eca78459582ba257acd1cc69c1852b34 315 Gene3D G3DSA:3.40.50.170 1 204 2.1E-53 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SMALA_RS39490 eca78459582ba257acd1cc69c1852b34 315 SUPERFAMILY SSF53328 1 203 1.07E-56 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SMALA_RS32405 fbc98200914390e4ce9303b02c91219d 355 SUPERFAMILY SSF103481 259 342 9.02E-9 T 29-03-2018 SMALA_RS32405 fbc98200914390e4ce9303b02c91219d 355 Pfam PF00892 EamA-like transporter family 64 194 4.5E-10 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SMALA_RS32405 fbc98200914390e4ce9303b02c91219d 355 Pfam PF00892 EamA-like transporter family 206 337 8.2E-12 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SMALA_RS32405 fbc98200914390e4ce9303b02c91219d 355 SUPERFAMILY SSF103481 99 196 1.83E-7 T 29-03-2018 SMALA_RS09585 b90040ead0b04d45e2d8d7f7883faa25 988 SUPERFAMILY SSF53187 131 407 1.4E-65 T 29-03-2018 SMALA_RS09585 b90040ead0b04d45e2d8d7f7883faa25 988 Pfam PF05547 Immune inhibitor A peptidase M6 744 913 9.1E-12 T 29-03-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 SMALA_RS09585 b90040ead0b04d45e2d8d7f7883faa25 988 Gene3D G3DSA:2.60.120.260 683 909 2.2E-17 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS09585 b90040ead0b04d45e2d8d7f7883faa25 988 Pfam PF00246 Zinc carboxypeptidase 135 395 6.5E-59 T 29-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 SMALA_RS09585 b90040ead0b04d45e2d8d7f7883faa25 988 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 176 190 7.1E-8 T 29-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 SMALA_RS09585 b90040ead0b04d45e2d8d7f7883faa25 988 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 316 329 7.1E-8 T 29-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 SMALA_RS09585 b90040ead0b04d45e2d8d7f7883faa25 988 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 149 161 7.1E-8 T 29-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 SMALA_RS09585 b90040ead0b04d45e2d8d7f7883faa25 988 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 262 270 7.1E-8 T 29-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 SMALA_RS09585 b90040ead0b04d45e2d8d7f7883faa25 988 ProSitePatterns PS00132 Zinc carboxypeptidases, zinc-binding region 1 signature. 176 198 - T 29-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 SMALA_RS09585 b90040ead0b04d45e2d8d7f7883faa25 988 SMART SM00631 123 412 8.3E-72 T 29-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 SMALA_RS09585 b90040ead0b04d45e2d8d7f7883faa25 988 Gene3D G3DSA:3.40.630.10 127 432 1.1E-54 T 29-03-2018 SMALA_RS03710 c412483226572635bc623059e157f334 367 Pfam PF03060 Nitronate monooxygenase 16 350 4.6E-49 T 29-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 SMALA_RS03710 c412483226572635bc623059e157f334 367 SUPERFAMILY SSF51412 93 309 6.41E-43 T 29-03-2018 SMALA_RS03710 c412483226572635bc623059e157f334 367 SUPERFAMILY SSF51412 22 58 6.41E-43 T 29-03-2018 SMALA_RS03710 c412483226572635bc623059e157f334 367 Gene3D G3DSA:3.20.20.70 4 364 2.6E-36 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS10480 4f9e6e584a2c987aca2f32363ad135ef 357 SUPERFAMILY SSF54001 240 347 5.4E-37 T 29-03-2018 SMALA_RS10480 4f9e6e584a2c987aca2f32363ad135ef 357 Gene3D G3DSA:3.90.1720.10 239 350 5.0E-35 T 29-03-2018 SMALA_RS10480 4f9e6e584a2c987aca2f32363ad135ef 357 Pfam PF00877 NlpC/P60 family 258 345 2.8E-25 T 29-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain SMALA_RS10480 4f9e6e584a2c987aca2f32363ad135ef 357 Gene3D G3DSA:1.20.120.330 47 205 4.6E-10 T 29-03-2018 SMALA_RS25630 e5bb989d16a7536644e22391bcf7181d 343 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 159 343 4.2E-26 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS25630 e5bb989d16a7536644e22391bcf7181d 343 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 67 107 1.6E-10 T 29-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain SMALA_RS25630 e5bb989d16a7536644e22391bcf7181d 343 Gene3D G3DSA:1.10.3720.10 70 332 2.4E-43 T 29-03-2018 SMALA_RS25630 e5bb989d16a7536644e22391bcf7181d 343 SUPERFAMILY SSF161098 138 328 3.01E-25 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS34405 f01c46ad0fc99e1a2dc9bc9521da6afe 222 Pfam PF09335 SNARE associated Golgi protein 32 160 3.3E-21 T 29-03-2018 IPR032816 SNARE associated Golgi protein SMALA_RS41185 8c02ffe7babd6da37ff6530644c4ac12 309 TIGRFAM TIGR03769 P_ac_wall_RPT: actinobacterial surface-anchored protein domain 185 225 1.6E-14 T 29-03-2018 IPR022435 Surface-anchored repeat, actinobacteria SMALA_RS41185 8c02ffe7babd6da37ff6530644c4ac12 309 TIGRFAM TIGR03773 anch_rpt_wall: putative ABC transporter-associated repeat protein 31 240 1.9E-63 T 29-03-2018 IPR022395 Conserved hypothetical protein CHP03773, ABC transporter-like SMALA_RS39040 a12836a58158b95494f23cba42fa7bb3 510 SUPERFAMILY SSF53850 31 492 3.62E-108 T 29-03-2018 SMALA_RS39040 a12836a58158b95494f23cba42fa7bb3 510 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 82 399 9.5E-65 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain SMALA_RS39040 a12836a58158b95494f23cba42fa7bb3 510 Gene3D G3DSA:3.40.190.10 155 288 7.2E-36 T 29-03-2018 SMALA_RS39040 a12836a58158b95494f23cba42fa7bb3 510 Gene3D G3DSA:3.10.105.10 289 481 4.8E-35 T 29-03-2018 SMALA_RS39040 a12836a58158b95494f23cba42fa7bb3 510 PIRSF PIRSF002741 1 502 5.4E-85 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 SMALA_RS39040 a12836a58158b95494f23cba42fa7bb3 510 Gene3D G3DSA:3.90.76.10 61 154 1.0E-26 T 29-03-2018 SMALA_RS21045 4329d0ae820d223e48ec8653f275b73a 113 SUPERFAMILY SSF55486 1 112 9.77E-38 T 29-03-2018 SMALA_RS21045 4329d0ae820d223e48ec8653f275b73a 113 Pfam PF06262 Zincin-like metallopeptidase 25 111 1.4E-32 T 29-03-2018 IPR010428 Zincin-like metallopeptidase SMALA_RS08885 3343140a4b2031969ce1e49640ed36ff 256 Pfam PF01464 Transglycosylase SLT domain 181 251 1.6E-7 T 29-03-2018 IPR008258 Transglycosylase SLT domain 1 SMALA_RS08885 3343140a4b2031969ce1e49640ed36ff 256 SUPERFAMILY SSF53955 164 250 8.13E-14 T 29-03-2018 IPR023346 Lysozyme-like domain SMALA_RS08885 3343140a4b2031969ce1e49640ed36ff 256 Gene3D G3DSA:1.10.530.10 58 255 7.2E-16 T 29-03-2018 SMALA_RS26610 b2ce7ea667872124677d84dbcfa7f0c8 1143 SUPERFAMILY SSF55874 536 663 8.91E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS26610 b2ce7ea667872124677d84dbcfa7f0c8 1143 Gene3D G3DSA:3.30.565.10 467 662 4.8E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS26610 b2ce7ea667872124677d84dbcfa7f0c8 1143 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 551 661 1.5E-7 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS26610 b2ce7ea667872124677d84dbcfa7f0c8 1143 SMART SM00387 547 663 4.5E-6 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS26610 b2ce7ea667872124677d84dbcfa7f0c8 1143 Gene3D G3DSA:1.20.5.400 376 445 1.0E-4 T 29-03-2018 SMALA_RS26610 b2ce7ea667872124677d84dbcfa7f0c8 1143 Pfam PF08376 Nitrate and nitrite sensing 80 305 1.1E-36 T 29-03-2018 IPR013587 Nitrate/nitrite sensing protein SMALA_RS04105 a585cbf9831412da1c9c482605c61faa 130 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 10 114 1.2E-10 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMALA_RS04105 a585cbf9831412da1c9c482605c61faa 130 SUPERFAMILY SSF54593 12 121 1.34E-23 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS04105 a585cbf9831412da1c9c482605c61faa 130 Gene3D G3DSA:3.10.180.10 7 126 5.2E-22 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS04450 501e2d8cca420817fe8a5b1938494417 462 TIGRFAM TIGR03173 pbuX: xanthine permease 20 427 4.7E-169 T 29-03-2018 IPR017588 Uric acid permease UacT-like GO:0006810|GO:0016021 SMALA_RS04450 501e2d8cca420817fe8a5b1938494417 462 Pfam PF00860 Permease family 17 393 4.6E-107 T 29-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 SMALA_RS04450 501e2d8cca420817fe8a5b1938494417 462 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 342 362 - T 29-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 SMALA_RS04450 501e2d8cca420817fe8a5b1938494417 462 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 16 425 5.8E-120 T 29-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 SMALA_RS16430 0a1b8348f7b0235a2780d93b53ac9590 450 SUPERFAMILY SSF103473 9 439 1.06E-77 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS16430 0a1b8348f7b0235a2780d93b53ac9590 450 Gene3D G3DSA:1.20.1250.20 12 214 6.9E-33 T 29-03-2018 SMALA_RS16430 0a1b8348f7b0235a2780d93b53ac9590 450 Gene3D G3DSA:1.20.1250.20 237 445 1.3E-31 T 29-03-2018 SMALA_RS16430 0a1b8348f7b0235a2780d93b53ac9590 450 ProSitePatterns PS00216 Sugar transport proteins signature 1. 76 93 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMALA_RS16430 0a1b8348f7b0235a2780d93b53ac9590 450 Pfam PF00083 Sugar (and other) transporter 54 435 3.9E-36 T 29-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 SMALA_RS42165 75782f8b0f7a55c3c6bdba47ccde285f 213 SUPERFAMILY SSF46894 113 187 4.08E-8 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS42165 75782f8b0f7a55c3c6bdba47ccde285f 213 SMART SM00421 122 181 4.7E-4 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS42165 75782f8b0f7a55c3c6bdba47ccde285f 213 Gene3D G3DSA:1.10.10.10 14 191 1.1E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS05225 7f17b5550f7c5e57e2a3dca67e0080cf 282 Pfam PF13560 Helix-turn-helix domain 15 72 1.7E-7 T 29-03-2018 SMALA_RS05225 7f17b5550f7c5e57e2a3dca67e0080cf 282 Gene3D G3DSA:1.10.260.40 4 119 1.7E-8 T 29-03-2018 SMALA_RS29180 4ff59a1fd1274078a9fe416675b7ad2b 266 Gene3D G3DSA:3.40.190.80 150 264 2.6E-26 T 29-03-2018 SMALA_RS29180 4ff59a1fd1274078a9fe416675b7ad2b 266 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 85 98 - T 29-03-2018 IPR020583 Inositol monophosphatase, metal-binding site SMALA_RS29180 4ff59a1fd1274078a9fe416675b7ad2b 266 Pfam PF00459 Inositol monophosphatase family 6 228 1.0E-56 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 SMALA_RS29180 4ff59a1fd1274078a9fe416675b7ad2b 266 PRINTS PR00377 Inositol monophosphatase superfamily signature 211 235 3.0E-42 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 SMALA_RS29180 4ff59a1fd1274078a9fe416675b7ad2b 266 PRINTS PR00377 Inositol monophosphatase superfamily signature 85 101 3.0E-42 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 SMALA_RS29180 4ff59a1fd1274078a9fe416675b7ad2b 266 PRINTS PR00377 Inositol monophosphatase superfamily signature 65 81 3.0E-42 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 SMALA_RS29180 4ff59a1fd1274078a9fe416675b7ad2b 266 PRINTS PR00377 Inositol monophosphatase superfamily signature 43 63 3.0E-42 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 SMALA_RS29180 4ff59a1fd1274078a9fe416675b7ad2b 266 PRINTS PR00377 Inositol monophosphatase superfamily signature 134 157 3.0E-42 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 SMALA_RS29180 4ff59a1fd1274078a9fe416675b7ad2b 266 PRINTS PR00377 Inositol monophosphatase superfamily signature 180 201 3.0E-42 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 SMALA_RS29180 4ff59a1fd1274078a9fe416675b7ad2b 266 SUPERFAMILY SSF56655 6 259 5.63E-74 T 29-03-2018 SMALA_RS29180 4ff59a1fd1274078a9fe416675b7ad2b 266 Gene3D G3DSA:3.30.540.10 2 149 1.5E-45 T 29-03-2018 SMALA_RS31040 63f5e65d3285bd773854e057cd42fb7d 180 Gene3D G3DSA:1.20.120.520 33 147 1.4E-18 T 29-03-2018 SMALA_RS31040 63f5e65d3285bd773854e057cd42fb7d 180 Gene3D G3DSA:1.20.120.520 1 32 0.17 T 29-03-2018 SMALA_RS31040 63f5e65d3285bd773854e057cd42fb7d 180 Pfam PF01814 Hemerythrin HHE cation binding domain 10 127 4.0E-14 T 29-03-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 SMALA_RS19555 f6885aedd825b17de7205800a3510a7e 200 SUPERFAMILY SSF53335 1 193 1.22E-39 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS19555 f6885aedd825b17de7205800a3510a7e 200 Pfam PF13649 Methyltransferase domain 38 129 8.8E-16 T 29-03-2018 SMALA_RS19555 f6885aedd825b17de7205800a3510a7e 200 Gene3D G3DSA:3.40.50.150 23 196 1.2E-27 T 29-03-2018 SMALA_RS27180 b4bdd26e594ec222cb956fbda5473432 391 Gene3D G3DSA:2.80.10.50 205 368 4.8E-12 T 29-03-2018 SMALA_RS27180 b4bdd26e594ec222cb956fbda5473432 391 SUPERFAMILY SSF50370 213 354 1.0E-7 T 29-03-2018 IPR000772 Ricin B, lectin domain SMALA_RS13140 07fb253147d98e0c67d09c2a0876e624 258 TIGRFAM TIGR03936 sam_1_link_chp: radical SAM-linked protein 3 216 1.8E-56 T 29-03-2018 IPR018768 Domain of unknown function DUF2344 SMALA_RS13140 07fb253147d98e0c67d09c2a0876e624 258 Pfam PF10105 Uncharacterized protein conserved in bacteria (DUF2344) 3 191 1.3E-50 T 29-03-2018 IPR018768 Domain of unknown function DUF2344 SMALA_RS21690 b3cd1d7efdb67d6aad4d3fbcc9bd7581 281 Pfam PF01261 Xylose isomerase-like TIM barrel 29 216 2.5E-17 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SMALA_RS21690 b3cd1d7efdb67d6aad4d3fbcc9bd7581 281 Gene3D G3DSA:3.20.20.150 7 267 7.0E-49 T 29-03-2018 SMALA_RS21690 b3cd1d7efdb67d6aad4d3fbcc9bd7581 281 SUPERFAMILY SSF51658 8 265 7.19E-45 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SMALA_RS32015 7c4c81a12ae5aba8b7c1d6a05d6eeb0f 252 Gene3D G3DSA:3.90.226.10 2 252 1.0E-65 T 29-03-2018 SMALA_RS32015 7c4c81a12ae5aba8b7c1d6a05d6eeb0f 252 SUPERFAMILY SSF52096 4 246 2.73E-68 T 29-03-2018 IPR029045 ClpP/crotonase-like domain SMALA_RS32015 7c4c81a12ae5aba8b7c1d6a05d6eeb0f 252 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 246 8.0E-41 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 SMALA_RS17975 aa3d9af00dff67cb20749c2798b07986 131 SUPERFAMILY SSF46785 3 114 4.13E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS17975 aa3d9af00dff67cb20749c2798b07986 131 Pfam PF03965 Penicillinase repressor 5 113 7.2E-23 T 29-03-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 SMALA_RS17975 aa3d9af00dff67cb20749c2798b07986 131 Gene3D G3DSA:1.10.10.10 6 70 2.3E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS07585 1e31c5ff49aa9858f9a6d85344b0b886 255 Gene3D G3DSA:3.40.50.150 1 239 1.5E-23 T 29-03-2018 SMALA_RS07585 1e31c5ff49aa9858f9a6d85344b0b886 255 SUPERFAMILY SSF53335 2 154 3.63E-24 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS07585 1e31c5ff49aa9858f9a6d85344b0b886 255 Pfam PF13649 Methyltransferase domain 32 122 4.5E-13 T 29-03-2018 SMALA_RS30780 b98143f4900a5d76f91dedc9b00dd7af 496 PRINTS PR01036 Tetracycline resistance protein TetB signature 93 115 4.9E-8 T 29-03-2018 SMALA_RS30780 b98143f4900a5d76f91dedc9b00dd7af 496 PRINTS PR01036 Tetracycline resistance protein TetB signature 33 57 4.9E-8 T 29-03-2018 SMALA_RS30780 b98143f4900a5d76f91dedc9b00dd7af 496 PRINTS PR01036 Tetracycline resistance protein TetB signature 278 303 4.9E-8 T 29-03-2018 SMALA_RS30780 b98143f4900a5d76f91dedc9b00dd7af 496 PRINTS PR01036 Tetracycline resistance protein TetB signature 155 179 4.9E-8 T 29-03-2018 SMALA_RS30780 b98143f4900a5d76f91dedc9b00dd7af 496 SUPERFAMILY SSF103473 19 217 2.75E-74 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS30780 b98143f4900a5d76f91dedc9b00dd7af 496 SUPERFAMILY SSF103473 265 471 2.75E-74 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS30780 b98143f4900a5d76f91dedc9b00dd7af 496 Gene3D G3DSA:1.20.1250.20 23 217 2.5E-40 T 29-03-2018 SMALA_RS30780 b98143f4900a5d76f91dedc9b00dd7af 496 Gene3D G3DSA:1.20.1250.20 276 492 6.8E-25 T 29-03-2018 SMALA_RS30780 b98143f4900a5d76f91dedc9b00dd7af 496 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 31 437 7.0E-83 T 29-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 SMALA_RS30780 b98143f4900a5d76f91dedc9b00dd7af 496 Pfam PF07690 Major Facilitator Superfamily 35 426 3.4E-60 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS12100 6422ecb2057482da5858432426c356e9 369 Gene3D G3DSA:3.40.50.2300 149 367 5.7E-33 T 29-03-2018 SMALA_RS12100 6422ecb2057482da5858432426c356e9 369 SUPERFAMILY SSF53822 41 355 4.71E-69 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SMALA_RS12100 6422ecb2057482da5858432426c356e9 369 Gene3D G3DSA:3.40.50.2300 43 148 3.2E-18 T 29-03-2018 SMALA_RS12100 6422ecb2057482da5858432426c356e9 369 Pfam PF13407 Periplasmic binding protein domain 45 322 1.2E-67 T 29-03-2018 IPR025997 Periplasmic binding protein SMALA_RS06590 a151a1f80c4cc722c9c9cda2fe237940 166 SMART SM00903 17 160 2.8E-51 T 29-03-2018 IPR002563 Flavin reductase like domain GO:0010181 SMALA_RS06590 a151a1f80c4cc722c9c9cda2fe237940 166 Pfam PF01613 Flavin reductase like domain 18 160 7.3E-33 T 29-03-2018 IPR002563 Flavin reductase like domain GO:0010181 SMALA_RS06590 a151a1f80c4cc722c9c9cda2fe237940 166 SUPERFAMILY SSF50475 4 163 2.21E-47 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS06590 a151a1f80c4cc722c9c9cda2fe237940 166 Gene3D G3DSA:2.30.110.10 5 166 5.0E-43 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS28830 37f5f7c7d3d4f2b71a7d3ec28e4dc467 180 Pfam PF05995 Cysteine dioxygenase type I 20 163 2.3E-45 T 29-03-2018 IPR010300 Cysteine dioxygenase type I GO:0005506|GO:0016702|GO:0055114 KEGG: 00270+1.13.11.20|KEGG: 00430+1.13.11.20|MetaCyc: PWY-5331|Reactome: R-HSA-1614558 SMALA_RS28830 37f5f7c7d3d4f2b71a7d3ec28e4dc467 180 Gene3D G3DSA:2.60.120.10 5 174 5.4E-28 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SMALA_RS28830 37f5f7c7d3d4f2b71a7d3ec28e4dc467 180 SUPERFAMILY SSF51182 17 168 6.22E-31 T 29-03-2018 IPR011051 RmlC-like cupin domain SMALA_RS20525 53f73200742b70619e581a14200afedc 419 Gene3D G3DSA:1.20.1250.20 1 186 2.2E-27 T 29-03-2018 SMALA_RS20525 53f73200742b70619e581a14200afedc 419 Pfam PF07690 Major Facilitator Superfamily 3 363 4.8E-30 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS20525 53f73200742b70619e581a14200afedc 419 SUPERFAMILY SSF103473 4 399 1.01E-42 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS20525 53f73200742b70619e581a14200afedc 419 Gene3D G3DSA:1.20.1250.20 200 404 7.4E-14 T 29-03-2018 SMALA_RS09420 eac3adaff6f2f34453a276704d7ab51f 482 SUPERFAMILY SSF63829 333 469 1.37E-9 T 29-03-2018 SMALA_RS09420 eac3adaff6f2f34453a276704d7ab51f 482 SUPERFAMILY SSF63829 197 255 1.37E-9 T 29-03-2018 SMALA_RS09420 eac3adaff6f2f34453a276704d7ab51f 482 Pfam PF05787 Bacterial protein of unknown function (DUF839) 158 469 1.1E-65 T 29-03-2018 IPR008557 Protein of unknown function DUF839 SMALA_RS09420 eac3adaff6f2f34453a276704d7ab51f 482 Pfam PF05787 Bacterial protein of unknown function (DUF839) 56 155 1.8E-16 T 29-03-2018 IPR008557 Protein of unknown function DUF839 SMALA_RS09420 eac3adaff6f2f34453a276704d7ab51f 482 Gene3D G3DSA:2.120.10.30 87 467 3.4E-9 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like SMALA_RS19780 952513cc8f72e69c55dd74d4f387ae3c 181 Gene3D G3DSA:3.30.240.10 27 105 4.2E-8 T 29-03-2018 SMALA_RS19780 952513cc8f72e69c55dd74d4f387ae3c 181 SUPERFAMILY SSF47413 22 74 5.63E-7 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS12405 8c9a46d7de31776a99eb55b63da12b3a 120 Gene3D G3DSA:2.60.120.10 4 116 6.2E-6 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SMALA_RS12405 8c9a46d7de31776a99eb55b63da12b3a 120 SUPERFAMILY SSF51182 19 103 4.24E-7 T 29-03-2018 IPR011051 RmlC-like cupin domain SMALA_RS19460 35b830cc190faa2997b0d6fc76601ced 145 Pfam PF04686 Streptomyces sporulation and cell division protein, SsgA 23 120 3.8E-32 T 29-03-2018 IPR006776 Sporulation-specific cell division protein SsgB GO:0051301 SMALA_RS19880 1bd094c423f8914e8d5934f7727c335e 217 Pfam PF02525 Flavodoxin-like fold 4 162 7.7E-32 T 29-03-2018 IPR003680 Flavodoxin-like fold SMALA_RS19880 1bd094c423f8914e8d5934f7727c335e 217 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 2 202 25.549 T 29-03-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 SMALA_RS19880 1bd094c423f8914e8d5934f7727c335e 217 SUPERFAMILY SSF52218 1 214 3.55E-36 T 29-03-2018 IPR029039 Flavoprotein-like domain SMALA_RS19880 1bd094c423f8914e8d5934f7727c335e 217 Gene3D G3DSA:3.40.50.360 1 215 2.8E-31 T 29-03-2018 IPR029039 Flavoprotein-like domain SMALA_RS16970 9bead9ddb54db0230ddce00054b55585 320 SUPERFAMILY SSF51735 19 281 9.88E-44 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS16970 9bead9ddb54db0230ddce00054b55585 320 Pfam PF00106 short chain dehydrogenase 25 164 2.0E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS16970 9bead9ddb54db0230ddce00054b55585 320 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 163 2.3E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS16970 9bead9ddb54db0230ddce00054b55585 320 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 100 111 2.3E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS16970 9bead9ddb54db0230ddce00054b55585 320 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 26 43 2.3E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS16970 9bead9ddb54db0230ddce00054b55585 320 Gene3D G3DSA:3.40.50.720 9 317 3.2E-50 T 29-03-2018 SMALA_RS05320 3c304af6704ab3fd83cf0780dbbd8277 246 Pfam PF14016 Protein of unknown function (DUF4232) 110 237 2.3E-27 T 29-03-2018 IPR025326 Protein of unknown function DUF4232 SMALA_RS05320 3c304af6704ab3fd83cf0780dbbd8277 246 Gene3D G3DSA:2.60.40.10 126 227 2.4E-4 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS03535 133380164643950668d15ca7c157ef1c 2154 Gene3D G3DSA:1.20.1170.10 1609 1904 0.0082 T 29-03-2018 SMALA_RS03535 133380164643950668d15ca7c157ef1c 2154 Gene3D G3DSA:1.20.1170.10 1243 1608 8.1E-4 T 29-03-2018 SMALA_RS03535 133380164643950668d15ca7c157ef1c 2154 Gene3D G3DSA:3.40.50.300 59 520 0.0017 T 29-03-2018 SMALA_RS00590 6d58d0b40562a322f9a9a2da51bcf8a0 142 Gene3D G3DSA:3.10.180.10 11 141 1.2E-20 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS00590 6d58d0b40562a322f9a9a2da51bcf8a0 142 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 20 134 1.3E-5 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMALA_RS00590 6d58d0b40562a322f9a9a2da51bcf8a0 142 SUPERFAMILY SSF54593 19 140 1.1E-18 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS10135 5530c3f3b5a84533080b383e8b9bb738 275 Gene3D G3DSA:3.40.30.10 86 275 2.9E-26 T 29-03-2018 SMALA_RS10135 5530c3f3b5a84533080b383e8b9bb738 275 Pfam PF13462 Thioredoxin 86 270 4.4E-37 T 29-03-2018 IPR012336 Thioredoxin-like fold SMALA_RS10135 5530c3f3b5a84533080b383e8b9bb738 275 SUPERFAMILY SSF52833 82 269 3.16E-17 T 29-03-2018 IPR012336 Thioredoxin-like fold SMALA_RS09775 8009e7ee131c8edcf52c5b06d2ea52ef 585 Pfam PF13406 Transglycosylase SLT domain 184 227 2.4E-6 T 29-03-2018 IPR031304 Transglycosylase SLT domain 2 SMALA_RS09775 8009e7ee131c8edcf52c5b06d2ea52ef 585 Gene3D G3DSA:1.10.530.10 98 366 4.6E-29 T 29-03-2018 SMALA_RS09775 8009e7ee131c8edcf52c5b06d2ea52ef 585 Gene3D G3DSA:2.60.40.10 367 462 4.2E-7 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS09775 8009e7ee131c8edcf52c5b06d2ea52ef 585 Gene3D G3DSA:2.60.40.10 468 580 0.065 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS09775 8009e7ee131c8edcf52c5b06d2ea52ef 585 SUPERFAMILY SSF53955 97 263 7.03E-37 T 29-03-2018 IPR023346 Lysozyme-like domain SMALA_RS26515 ef71036cf01f2558342033a337238c67 316 Gene3D G3DSA:3.40.50.720 9 313 1.2E-36 T 29-03-2018 SMALA_RS26515 ef71036cf01f2558342033a337238c67 316 Pfam PF01370 NAD dependent epimerase/dehydratase family 15 232 6.0E-18 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 SMALA_RS26515 ef71036cf01f2558342033a337238c67 316 SUPERFAMILY SSF51735 8 309 5.11E-43 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS01480 6cc24de150b00d5609d686eb6a0a5942 268 SUPERFAMILY SSF51230 63 135 1.26E-5 T 29-03-2018 IPR011053 Single hybrid motif SMALA_RS01480 6cc24de150b00d5609d686eb6a0a5942 268 Pfam PF13437 HlyD family secretion protein 107 195 2.0E-8 T 29-03-2018 SMALA_RS01480 6cc24de150b00d5609d686eb6a0a5942 268 Gene3D G3DSA:2.40.50.100 6 83 0.0011 T 29-03-2018 SMALA_RS01480 6cc24de150b00d5609d686eb6a0a5942 268 Gene3D G3DSA:2.40.50.100 84 135 3.6E-6 T 29-03-2018 SMALA_RS30990 2f3da674361536ea362d1fbd868228ed 127 Pfam PF11387 Protein of unknown function (DUF2795) 73 117 3.6E-10 T 29-03-2018 IPR021527 Protein of unknown function DUF2795 SMALA_RS14970 82cfd6bc6b20fd3f76894def7be05657 266 Pfam PF06182 ABC-2 family transporter protein 40 261 7.5E-15 T 29-03-2018 IPR010390 Protein of unknown function DUF990 SMALA_RS01460 23736a2204fa62960fe67a2e4261b749 563 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 130 250 3.0E-13 T 29-03-2018 SMALA_RS28790 1fac1823cde5092b2d436a87141e9df8 246 Pfam PF03591 AzlC protein 30 165 1.9E-28 T 29-03-2018 IPR011606 Branched-chain amino acid transport, permease SMALA_RS23905 945f1034a54e6927bbf6594a893a6069 255 Gene3D G3DSA:3.40.50.1820 2 255 1.2E-21 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS23905 945f1034a54e6927bbf6594a893a6069 255 Pfam PF12697 Alpha/beta hydrolase family 4 240 1.4E-12 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS23905 945f1034a54e6927bbf6594a893a6069 255 SUPERFAMILY SSF53474 2 251 4.42E-26 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS24210 879cae8487315feccc2f4d7603833ca7 131 SUPERFAMILY SSF88723 2 123 1.26E-13 T 29-03-2018 IPR029060 PIN domain-like SMALA_RS24210 879cae8487315feccc2f4d7603833ca7 131 Pfam PF01850 PIN domain 2 119 4.6E-9 T 29-03-2018 IPR002716 PIN domain SMALA_RS24210 879cae8487315feccc2f4d7603833ca7 131 Gene3D G3DSA:3.40.50.1010 1 131 2.0E-17 T 29-03-2018 IPR029060 PIN domain-like SMALA_RS24210 879cae8487315feccc2f4d7603833ca7 131 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 128 10.865 T 29-03-2018 IPR022907 VapC family GO:0004540 SMALA_RS12800 94801801d07a321b4e1d1b6e533bd7cc 142 Pfam PF13581 Histidine kinase-like ATPase domain 22 115 2.4E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS12800 94801801d07a321b4e1d1b6e533bd7cc 142 Gene3D G3DSA:3.30.565.10 10 142 3.3E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS12800 94801801d07a321b4e1d1b6e533bd7cc 142 SUPERFAMILY SSF55874 43 124 1.28E-7 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS35805 408201e6d8f5d544d628811c837a2f75 372 SUPERFAMILY SSF103481 21 113 2.48E-6 T 29-03-2018 SMALA_RS27110 4999f1ee6c4e8f1609fa82d2aa5cfaa8 453 SUPERFAMILY SSF103473 51 446 5.62E-29 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS27110 4999f1ee6c4e8f1609fa82d2aa5cfaa8 453 Pfam PF07690 Major Facilitator Superfamily 58 368 3.2E-11 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS27110 4999f1ee6c4e8f1609fa82d2aa5cfaa8 453 Gene3D G3DSA:1.20.1250.20 253 450 3.4E-13 T 29-03-2018 SMALA_RS27110 4999f1ee6c4e8f1609fa82d2aa5cfaa8 453 Gene3D G3DSA:1.20.1250.20 42 240 6.5E-11 T 29-03-2018 SMALA_RS36665 2548b4723eb8bcc9145a72d4ce1eccea 389 SMART SM00854 53 303 6.3E-74 T 29-03-2018 IPR019079 Capsule synthesis protein, CapA SMALA_RS36665 2548b4723eb8bcc9145a72d4ce1eccea 389 Gene3D G3DSA:3.60.21.10 41 376 2.0E-55 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SMALA_RS36665 2548b4723eb8bcc9145a72d4ce1eccea 389 Pfam PF09587 Bacterial capsule synthesis protein PGA_cap 53 301 6.4E-67 T 29-03-2018 IPR019079 Capsule synthesis protein, CapA SMALA_RS36665 2548b4723eb8bcc9145a72d4ce1eccea 389 SUPERFAMILY SSF56300 53 302 3.74E-33 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SMALA_RS23520 ce442bf9ed58a09e5f74d3e834b19260 154 Pfam PF12802 MarR family 35 90 8.2E-9 T 29-03-2018 SMALA_RS23520 ce442bf9ed58a09e5f74d3e834b19260 154 SMART SM00347 27 127 1.6E-4 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS23520 ce442bf9ed58a09e5f74d3e834b19260 154 Gene3D G3DSA:1.10.10.10 2 147 1.6E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS23520 ce442bf9ed58a09e5f74d3e834b19260 154 SUPERFAMILY SSF46785 10 140 1.41E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS28550 18087e68b56fb797049e7c8e06874c85 253 Gene3D G3DSA:3.30.1310.10 137 226 9.5E-8 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family SMALA_RS28550 18087e68b56fb797049e7c8e06874c85 253 Gene3D G3DSA:3.30.1310.10 2 98 3.3E-10 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family SMALA_RS22080 d30012834e16e7eccecb2ae0536b6fae 230 Pfam PF01209 ubiE/COQ5 methyltransferase family 11 229 8.9E-58 T 29-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 SMALA_RS22080 d30012834e16e7eccecb2ae0536b6fae 230 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 137 151 - T 29-03-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 SMALA_RS22080 d30012834e16e7eccecb2ae0536b6fae 230 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 4 229 34.028 T 29-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 SMALA_RS22080 d30012834e16e7eccecb2ae0536b6fae 230 Gene3D G3DSA:3.40.50.150 2 229 5.7E-40 T 29-03-2018 SMALA_RS22080 d30012834e16e7eccecb2ae0536b6fae 230 SUPERFAMILY SSF53335 4 226 1.55E-45 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS22080 d30012834e16e7eccecb2ae0536b6fae 230 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 13 229 6.1E-70 T 29-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 SMALA_RS22600 d94e7ddaef44ab244394a4f3a44e0445 61 Pfam PF00253 Ribosomal protein S14p/S29e 9 60 1.6E-24 T 29-03-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS22600 d94e7ddaef44ab244394a4f3a44e0445 61 Gene3D G3DSA:4.10.830.10 1 61 5.8E-23 T 29-03-2018 SMALA_RS22600 d94e7ddaef44ab244394a4f3a44e0445 61 Hamap MF_01364_B 30S ribosomal protein S14 type Z [rpsZ]. 1 61 25.525 T 29-03-2018 IPR023053 Ribosomal protein S14, type Z SMALA_RS22600 d94e7ddaef44ab244394a4f3a44e0445 61 ProSitePatterns PS00527 Ribosomal protein S14 signature. 23 45 - T 29-03-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMALA_RS22600 d94e7ddaef44ab244394a4f3a44e0445 61 SUPERFAMILY SSF57716 4 61 1.43E-21 T 29-03-2018 SMALA_RS41135 d7f132f81505fefdec158b6e3a517e8f 340 SUPERFAMILY SSF161098 107 330 1.96E-50 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS41135 d7f132f81505fefdec158b6e3a517e8f 340 Gene3D G3DSA:1.10.3720.10 61 339 5.4E-41 T 29-03-2018 SMALA_RS41135 d7f132f81505fefdec158b6e3a517e8f 340 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 140 333 2.0E-15 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS28660 a02a41add703de5acf3002c1fa4d6b34 153 SUPERFAMILY SSF48452 105 144 8.22E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS28660 a02a41add703de5acf3002c1fa4d6b34 153 Gene3D G3DSA:1.25.40.10 48 150 1.1E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS26590 c5d2dd7582c331416940abdddbd4c811 186 Gene3D G3DSA:3.90.1570.10 2 183 9.2E-29 T 29-03-2018 SMALA_RS26590 c5d2dd7582c331416940abdddbd4c811 186 SUPERFAMILY SSF52980 17 178 1.61E-11 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 SMALA_RS26590 c5d2dd7582c331416940abdddbd4c811 186 Pfam PF05685 Putative restriction endonuclease 17 177 7.3E-24 T 29-03-2018 IPR008538 Domain of unknown function DUF820 SMALA_RS12395 63f9188abc91a73c2ceb7db7f79dfd10 236 Pfam PF02698 DUF218 domain 58 174 2.1E-24 T 29-03-2018 IPR003848 Domain of unknown function DUF218 SMALA_RS12395 63f9188abc91a73c2ceb7db7f79dfd10 236 Gene3D G3DSA:3.40.50.620 47 181 5.6E-24 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS09080 a50d37e7f10e4605287125fcda522bcf 593 Gene3D G3DSA:1.50.10.10 190 544 2.7E-98 T 29-03-2018 SMALA_RS09080 a50d37e7f10e4605287125fcda522bcf 593 Pfam PF00723 Glycosyl hydrolases family 15 217 536 4.4E-67 T 29-03-2018 IPR011613 Glycoside hydrolase family 15/Phosphorylase b kinase regulatory chain family Reactome: R-HSA-70221 SMALA_RS09080 a50d37e7f10e4605287125fcda522bcf 593 Pfam PF00723 Glycosyl hydrolases family 15 538 581 5.7E-5 T 29-03-2018 IPR011613 Glycoside hydrolase family 15/Phosphorylase b kinase regulatory chain family Reactome: R-HSA-70221 SMALA_RS09080 a50d37e7f10e4605287125fcda522bcf 593 SUPERFAMILY SSF48208 191 589 3.53E-104 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 SMALA_RS30225 25dfee866218821bb2f86c9a61cb08dd 453 Gene3D G3DSA:3.40.50.300 208 350 2.1E-12 T 29-03-2018 SMALA_RS30225 25dfee866218821bb2f86c9a61cb08dd 453 Pfam PF13476 AAA domain 8 60 5.0E-6 T 29-03-2018 SMALA_RS30225 25dfee866218821bb2f86c9a61cb08dd 453 Gene3D G3DSA:3.40.50.300 1 207 6.2E-10 T 29-03-2018 SMALA_RS30225 25dfee866218821bb2f86c9a61cb08dd 453 SUPERFAMILY SSF52540 239 355 6.91E-21 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS30225 25dfee866218821bb2f86c9a61cb08dd 453 SUPERFAMILY SSF52540 2 207 6.91E-21 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS30225 25dfee866218821bb2f86c9a61cb08dd 453 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 255 344 8.2E-15 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 SMALA_RS01575 a88605ca225d0195fef0e0ce012ce4a1 233 Pfam PF12697 Alpha/beta hydrolase family 4 224 3.4E-13 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS01575 a88605ca225d0195fef0e0ce012ce4a1 233 SUPERFAMILY SSF53474 4 228 6.87E-25 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS01575 a88605ca225d0195fef0e0ce012ce4a1 233 Gene3D G3DSA:3.40.50.1820 4 231 7.3E-19 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS29585 3233704cb5381cb0d87801e0820cf9f9 120 SUPERFAMILY SSF101386 14 117 1.01E-30 T 29-03-2018 SMALA_RS29585 3233704cb5381cb0d87801e0820cf9f9 120 Pfam PF12643 MazG-like family 45 116 4.9E-10 T 29-03-2018 IPR025984 dCTP pyrophosphatase 1 GO:0009143|GO:0047429 KEGG: 00240+3.6.1.12|Reactome: R-HSA-499943 SMALA_RS29585 3233704cb5381cb0d87801e0820cf9f9 120 PIRSF PIRSF029826 7 120 3.7E-39 T 29-03-2018 IPR025984 dCTP pyrophosphatase 1 GO:0009143|GO:0047429 KEGG: 00240+3.6.1.12|Reactome: R-HSA-499943 SMALA_RS29585 3233704cb5381cb0d87801e0820cf9f9 120 Gene3D G3DSA:1.10.287.1080 4 118 6.1E-23 T 29-03-2018 SMALA_RS37810 7e642ed1e897ddf434a6a77aba88b845 363 PRINTS PR00359 B-class P450 signature 301 310 5.9E-46 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS37810 7e642ed1e897ddf434a6a77aba88b845 363 PRINTS PR00359 B-class P450 signature 252 279 5.9E-46 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS37810 7e642ed1e897ddf434a6a77aba88b845 363 PRINTS PR00359 B-class P450 signature 103 119 5.9E-46 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS37810 7e642ed1e897ddf434a6a77aba88b845 363 PRINTS PR00359 B-class P450 signature 234 245 5.9E-46 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS37810 7e642ed1e897ddf434a6a77aba88b845 363 PRINTS PR00359 B-class P450 signature 120 135 5.9E-46 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS37810 7e642ed1e897ddf434a6a77aba88b845 363 PRINTS PR00359 B-class P450 signature 310 321 5.9E-46 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS37810 7e642ed1e897ddf434a6a77aba88b845 363 PRINTS PR00359 B-class P450 signature 157 179 5.9E-46 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS37810 7e642ed1e897ddf434a6a77aba88b845 363 PRINTS PR00359 B-class P450 signature 280 295 5.9E-46 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS37810 7e642ed1e897ddf434a6a77aba88b845 363 PRINTS PR00359 B-class P450 signature 56 67 5.9E-46 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS37810 7e642ed1e897ddf434a6a77aba88b845 363 PRINTS PR00385 P450 superfamily signature 234 245 4.3E-5 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS37810 7e642ed1e897ddf434a6a77aba88b845 363 PRINTS PR00385 P450 superfamily signature 301 310 4.3E-5 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS37810 7e642ed1e897ddf434a6a77aba88b845 363 PRINTS PR00385 P450 superfamily signature 310 321 4.3E-5 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS37810 7e642ed1e897ddf434a6a77aba88b845 363 PRINTS PR00385 P450 superfamily signature 199 216 4.3E-5 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS37810 7e642ed1e897ddf434a6a77aba88b845 363 Pfam PF00067 Cytochrome P450 182 332 2.7E-22 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS37810 7e642ed1e897ddf434a6a77aba88b845 363 Gene3D G3DSA:1.10.630.10 1 363 3.4E-67 T 29-03-2018 SMALA_RS37810 7e642ed1e897ddf434a6a77aba88b845 363 SUPERFAMILY SSF48264 3 361 2.23E-85 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS22085 2b3ec63ab507b7775a10f181eee3a7fb 423 SUPERFAMILY SSF51905 291 397 3.18E-44 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS22085 2b3ec63ab507b7775a10f181eee3a7fb 423 SUPERFAMILY SSF51905 5 184 3.18E-44 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS22085 2b3ec63ab507b7775a10f181eee3a7fb 423 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 1.2E-10 T 29-03-2018 SMALA_RS22085 2b3ec63ab507b7775a10f181eee3a7fb 423 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 294 309 1.2E-10 T 29-03-2018 SMALA_RS22085 2b3ec63ab507b7775a10f181eee3a7fb 423 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 157 172 1.2E-10 T 29-03-2018 SMALA_RS22085 2b3ec63ab507b7775a10f181eee3a7fb 423 Gene3D G3DSA:3.50.50.60 1 165 1.6E-17 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS22085 2b3ec63ab507b7775a10f181eee3a7fb 423 Gene3D G3DSA:3.30.9.10 166 343 1.9E-47 T 29-03-2018 SMALA_RS22085 2b3ec63ab507b7775a10f181eee3a7fb 423 Pfam PF01494 FAD binding domain 6 185 1.8E-12 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 SMALA_RS22085 2b3ec63ab507b7775a10f181eee3a7fb 423 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 7 329 1.7E-88 T 29-03-2018 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 SMALA_RS21100 845b48293852376ca26f040610eaae87 320 Gene3D G3DSA:3.20.20.100 10 320 7.2E-75 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS21100 845b48293852376ca26f040610eaae87 320 Pfam PF00248 Aldo/keto reductase family 21 318 4.8E-67 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS21100 845b48293852376ca26f040610eaae87 320 SUPERFAMILY SSF51430 16 318 7.07E-81 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS21100 845b48293852376ca26f040610eaae87 320 PRINTS PR00069 Aldo-keto reductase signature 115 133 9.9E-6 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMALA_RS21100 845b48293852376ca26f040610eaae87 320 PRINTS PR00069 Aldo-keto reductase signature 146 163 9.9E-6 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMALA_RS08375 c15ce74d64899cc224539f2d6d55a916 309 Pfam PF00583 Acetyltransferase (GNAT) family 42 130 1.1E-8 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SMALA_RS08375 c15ce74d64899cc224539f2d6d55a916 309 Gene3D G3DSA:3.40.630.30 146 306 4.4E-14 T 29-03-2018 SMALA_RS08375 c15ce74d64899cc224539f2d6d55a916 309 Gene3D G3DSA:3.40.630.30 1 145 7.4E-19 T 29-03-2018 SMALA_RS08375 c15ce74d64899cc224539f2d6d55a916 309 SUPERFAMILY SSF55729 154 303 2.13E-12 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS08375 c15ce74d64899cc224539f2d6d55a916 309 SUPERFAMILY SSF55729 1 136 1.01E-17 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS09200 6eab0f5846b68ff04a329b604c26067d 166 SUPERFAMILY SSF159664 16 144 2.09E-34 T 29-03-2018 IPR002750 CobE/GbiG C-terminal domain GO:0009236 SMALA_RS09200 6eab0f5846b68ff04a329b604c26067d 166 Gene3D G3DSA:3.30.420.180 15 151 2.1E-43 T 29-03-2018 IPR002750 CobE/GbiG C-terminal domain GO:0009236 SMALA_RS09200 6eab0f5846b68ff04a329b604c26067d 166 Pfam PF01890 Cobalamin synthesis G C-terminus 17 141 2.0E-32 T 29-03-2018 IPR002750 CobE/GbiG C-terminal domain GO:0009236 SMALA_RS04775 ef3e073aa446a9e3eac9593ddf548d6e 316 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 9.4E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS04775 ef3e073aa446a9e3eac9593ddf548d6e 316 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 93 104 9.4E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS04775 ef3e073aa446a9e3eac9593ddf548d6e 316 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 194 213 9.4E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS04775 ef3e073aa446a9e3eac9593ddf548d6e 316 Gene3D G3DSA:3.40.50.720 1 316 8.1E-38 T 29-03-2018 SMALA_RS04775 ef3e073aa446a9e3eac9593ddf548d6e 316 Pfam PF00106 short chain dehydrogenase 7 152 3.9E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS04775 ef3e073aa446a9e3eac9593ddf548d6e 316 SUPERFAMILY SSF51735 4 237 6.56E-31 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS31765 7872dc1b3480aec64220ef8f6fc1a885 238 Pfam PF06386 Gas vesicle synthesis protein GvpL/GvpF 3 237 1.5E-55 T 29-03-2018 IPR009430 Gas vesicle protein GvpL/GvpF GO:0031411|GO:0031412 SMALA_RS31765 7872dc1b3480aec64220ef8f6fc1a885 238 Gene3D G3DSA:3.20.20.30 11 216 3.6E-4 T 29-03-2018 SMALA_RS29545 73c6e43b48a544207652322c7b5634d4 329 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 113 190 1.5E-26 T 29-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SMALA_RS29545 73c6e43b48a544207652322c7b5634d4 329 Gene3D G3DSA:3.40.47.10 3 167 1.9E-34 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS29545 73c6e43b48a544207652322c7b5634d4 329 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 8 328 56.449 T 29-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SMALA_RS29545 73c6e43b48a544207652322c7b5634d4 329 Gene3D G3DSA:3.40.47.10 168 328 1.6E-33 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS29545 73c6e43b48a544207652322c7b5634d4 329 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 10 327 4.2E-99 T 29-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SMALA_RS29545 73c6e43b48a544207652322c7b5634d4 329 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 238 327 1.9E-26 T 29-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SMALA_RS29545 73c6e43b48a544207652322c7b5634d4 329 SUPERFAMILY SSF53901 8 327 3.03E-57 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS00730 b9fa1ef87e9f062bf2cef06b19dea07c 125 SUPERFAMILY SSF54427 10 116 1.25E-19 T 29-03-2018 IPR032710 NTF2-like domain SMALA_RS00730 b9fa1ef87e9f062bf2cef06b19dea07c 125 Pfam PF12680 SnoaL-like domain 16 100 9.0E-11 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain SMALA_RS00730 b9fa1ef87e9f062bf2cef06b19dea07c 125 Gene3D G3DSA:3.10.450.50 1 116 1.5E-16 T 29-03-2018 SMALA_RS01855 3c2cfbca86390c755b3eb0575545856e 488 Gene3D G3DSA:1.50.10.20 157 488 8.6E-51 T 29-03-2018 SMALA_RS01855 3c2cfbca86390c755b3eb0575545856e 488 Pfam PF03663 Glycosyl hydrolase family 76 167 486 2.3E-43 T 29-03-2018 IPR005198 Glycoside hydrolase, family 76 KEGG: 00052+3.2.1.10|KEGG: 00500+3.2.1.10 SMALA_RS01855 3c2cfbca86390c755b3eb0575545856e 488 SUPERFAMILY SSF48208 176 453 6.24E-46 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 SMALA_RS26400 21859effbd8d6bb86cad1427ce263553 219 Pfam PF03767 HAD superfamily, subfamily IIIB (Acid phosphatase) 112 214 9.1E-20 T 29-03-2018 IPR005519 Acid phosphatase, class B-like SMALA_RS26400 21859effbd8d6bb86cad1427ce263553 219 Pfam PF03767 HAD superfamily, subfamily IIIB (Acid phosphatase) 33 107 7.1E-7 T 29-03-2018 IPR005519 Acid phosphatase, class B-like SMALA_RS26400 21859effbd8d6bb86cad1427ce263553 219 SUPERFAMILY SSF56784 86 202 1.78E-11 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS26400 21859effbd8d6bb86cad1427ce263553 219 Gene3D G3DSA:3.40.50.1000 87 210 2.3E-9 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS39255 e653555575b1c006a8b578f9cff274e0 113 Gene3D G3DSA:3.40.50.2000 1 110 7.7E-6 T 29-03-2018 SMALA_RS39255 e653555575b1c006a8b578f9cff274e0 113 SUPERFAMILY SSF53756 4 50 2.87E-5 T 29-03-2018 SMALA_RS04035 0175d1c3fd3c91b47e31457b98fa84f7 127 Pfam PF09851 Short C-terminal domain 98 125 4.1E-6 T 29-03-2018 IPR018649 SHOCT domain SMALA_RS04035 0175d1c3fd3c91b47e31457b98fa84f7 127 Pfam PF13396 Phospholipase_D-nuclease N-terminal 19 65 7.3E-7 T 29-03-2018 IPR027379 Cardiolipin synthase N-terminal SMALA_RS34940 3eb31f537497124815f0d34cc2d8666c 286 SUPERFAMILY SSF51735 4 278 6.63E-39 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS34940 3eb31f537497124815f0d34cc2d8666c 286 Gene3D G3DSA:3.90.25.10 143 280 4.1E-5 T 29-03-2018 SMALA_RS34940 3eb31f537497124815f0d34cc2d8666c 286 Gene3D G3DSA:3.40.50.720 1 142 1.1E-14 T 29-03-2018 SMALA_RS34940 3eb31f537497124815f0d34cc2d8666c 286 Pfam PF13460 NAD(P)H-binding 10 179 1.2E-6 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS35815 2f82e841df3967946f2ae70eb373b60d 777 SUPERFAMILY SSF48208 260 710 8.5E-45 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 SMALA_RS35815 2f82e841df3967946f2ae70eb373b60d 777 Gene3D G3DSA:1.50.10.10 216 640 2.2E-67 T 29-03-2018 SMALA_RS35815 2f82e841df3967946f2ae70eb373b60d 777 Gene3D G3DSA:2.60.40.1180 641 754 2.2E-14 T 29-03-2018 SMALA_RS26090 8a5e7595f3f846f85e57f2a1a9a83804 155 Pfam PF02391 MoaE protein 26 136 1.2E-35 T 29-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 SMALA_RS26090 8a5e7595f3f846f85e57f2a1a9a83804 155 Gene3D G3DSA:3.90.1170.40 19 155 5.1E-47 T 29-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 SMALA_RS26090 8a5e7595f3f846f85e57f2a1a9a83804 155 SUPERFAMILY SSF54690 23 154 5.62E-40 T 29-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 SMALA_RS01080 cfd80ceb84f8153e1cdffc1c2267e4fb 518 Pfam PF03611 PTS system sugar-specific permease component 14 428 1.4E-129 T 29-03-2018 IPR004703 Phosphotransferase system, sugar-specific permease component GO:0009401|GO:0016021 SMALA_RS30770 6744c606deb0457746d8fa05b46b4a4d 333 Gene3D G3DSA:3.20.20.30 1 333 4.4E-64 T 29-03-2018 SMALA_RS30770 6744c606deb0457746d8fa05b46b4a4d 333 SUPERFAMILY SSF51679 1 329 3.01E-60 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS30770 6744c606deb0457746d8fa05b46b4a4d 333 TIGRFAM TIGR03842 F420_CPS_4043: F420-dependent oxidoreductase, CPS_4043 family 2 331 1.6E-179 T 29-03-2018 IPR022315 F420-dependent oxidoreductase-predicted, CPS4043 SMALA_RS30770 6744c606deb0457746d8fa05b46b4a4d 333 Pfam PF00296 Luciferase-like monooxygenase 6 306 3.6E-55 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS40705 7103a2bf66f4b5aa2700563cff49effd 469 SUPERFAMILY SSF51556 58 374 5.39E-50 T 29-03-2018 IPR032466 Metal-dependent hydrolase SMALA_RS40705 7103a2bf66f4b5aa2700563cff49effd 469 SUPERFAMILY SSF51338 1 58 4.87E-24 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS40705 7103a2bf66f4b5aa2700563cff49effd 469 SUPERFAMILY SSF51338 374 446 4.87E-24 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS40705 7103a2bf66f4b5aa2700563cff49effd 469 Pfam PF01979 Amidohydrolase family 55 187 1.6E-7 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 SMALA_RS40705 7103a2bf66f4b5aa2700563cff49effd 469 Pfam PF01979 Amidohydrolase family 241 423 6.8E-18 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 SMALA_RS40705 7103a2bf66f4b5aa2700563cff49effd 469 Gene3D G3DSA:3.20.20.140 72 391 3.4E-41 T 29-03-2018 SMALA_RS40705 7103a2bf66f4b5aa2700563cff49effd 469 Gene3D G3DSA:2.30.40.10 1 71 1.1E-17 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMALA_RS41535 91b58b9c7a824740aafd429620632c0a 294 Pfam PF01614 Bacterial transcriptional regulator 137 233 2.8E-24 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal SMALA_RS41535 91b58b9c7a824740aafd429620632c0a 294 Pfam PF09339 IclR helix-turn-helix domain 24 74 7.6E-16 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMALA_RS41535 91b58b9c7a824740aafd429620632c0a 294 SUPERFAMILY SSF46785 23 90 3.76E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS41535 91b58b9c7a824740aafd429620632c0a 294 SUPERFAMILY SSF55781 77 252 1.47E-37 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS41535 91b58b9c7a824740aafd429620632c0a 294 Gene3D G3DSA:3.30.450.40 92 267 1.4E-39 T 29-03-2018 IPR029016 GAF domain-like SMALA_RS41535 91b58b9c7a824740aafd429620632c0a 294 SMART SM00346 21 109 1.6E-23 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMALA_RS41535 91b58b9c7a824740aafd429620632c0a 294 Gene3D G3DSA:1.10.10.10 7 80 3.1E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS26505 f596e6e8d09fe44a49e29497b8e04be9 285 Pfam PF13349 Putative adhesin 86 263 2.2E-9 T 29-03-2018 IPR025164 Putative adhesin SMALA_RS18945 7b90d89e7afd92ee132f7394c35d3118 371 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 169 355 1.1E-38 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS18945 7b90d89e7afd92ee132f7394c35d3118 371 SMART SM00331 143 356 2.5E-32 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS18945 7b90d89e7afd92ee132f7394c35d3118 371 SUPERFAMILY SSF81606 157 353 4.71E-6 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS18945 7b90d89e7afd92ee132f7394c35d3118 371 Gene3D G3DSA:3.60.40.10 106 358 1.0E-27 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS28755 d96e0e275838157702083888e263d77e 172 Pfam PF02464 Competence-damaged protein 7 155 6.9E-50 T 29-03-2018 IPR008136 CinA, C-terminal SMALA_RS28755 d96e0e275838157702083888e263d77e 172 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 12 154 9.7E-38 T 29-03-2018 IPR008136 CinA, C-terminal SMALA_RS28755 d96e0e275838157702083888e263d77e 172 SUPERFAMILY SSF142433 6 157 2.88E-47 T 29-03-2018 IPR008136 CinA, C-terminal SMALA_RS28755 d96e0e275838157702083888e263d77e 172 Gene3D G3DSA:3.90.950.20 2 162 8.1E-61 T 29-03-2018 SMALA_RS11915 f3689a803f18cf4c277789ae9acda729 242 Pfam PF02342 TerD domain 28 161 5.3E-6 T 29-03-2018 IPR003325 TerD domain GO:0006950 SMALA_RS11915 f3689a803f18cf4c277789ae9acda729 242 Gene3D G3DSA:2.60.60.30 40 227 2.6E-30 T 29-03-2018 SMALA_RS17820 05d66077af63d9d3ab1d33354cd8e7bb 270 Gene3D G3DSA:3.40.50.150 16 256 3.3E-14 T 29-03-2018 SMALA_RS17820 05d66077af63d9d3ab1d33354cd8e7bb 270 SUPERFAMILY SSF53335 19 178 2.65E-12 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS24355 887769668d54e8fc47b922951e0865c8 365 Gene3D G3DSA:1.25.40.10 64 236 0.0049 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS24355 887769668d54e8fc47b922951e0865c8 365 SUPERFAMILY SSF48452 157 212 6.42E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS24355 887769668d54e8fc47b922951e0865c8 365 SUPERFAMILY SSF48452 280 322 6.42E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS24355 887769668d54e8fc47b922951e0865c8 365 Gene3D G3DSA:1.25.40.10 237 326 0.015 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS27905 5ea9e7389ff7c469ca0a7af1e865a78d 212 Pfam PF13411 MerR HTH family regulatory protein 1 70 5.3E-14 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS27905 5ea9e7389ff7c469ca0a7af1e865a78d 212 SUPERFAMILY SSF46955 1 84 7.78E-12 T 29-03-2018 IPR009061 Putative DNA-binding domain SMALA_RS27905 5ea9e7389ff7c469ca0a7af1e865a78d 212 SMART SM00422 1 71 7.8E-5 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS27905 5ea9e7389ff7c469ca0a7af1e865a78d 212 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 1.3E-5 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS27905 5ea9e7389ff7c469ca0a7af1e865a78d 212 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 1.3E-5 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS27905 5ea9e7389ff7c469ca0a7af1e865a78d 212 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 1.3E-5 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS27905 5ea9e7389ff7c469ca0a7af1e865a78d 212 Gene3D G3DSA:1.10.1660.10 1 152 3.9E-16 T 29-03-2018 SMALA_RS21405 daaf8dc46ed41287b415dc1b24158670 288 Gene3D G3DSA:3.20.20.100 9 288 3.7E-57 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS21405 daaf8dc46ed41287b415dc1b24158670 288 SUPERFAMILY SSF51430 17 286 2.88E-57 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS21405 daaf8dc46ed41287b415dc1b24158670 288 Pfam PF00248 Aldo/keto reductase family 18 284 5.0E-43 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS21405 daaf8dc46ed41287b415dc1b24158670 288 PRINTS PR00069 Aldo-keto reductase signature 47 71 2.3E-6 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMALA_RS21405 daaf8dc46ed41287b415dc1b24158670 288 PRINTS PR00069 Aldo-keto reductase signature 149 166 2.3E-6 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMALA_RS23920 c47ca280bb8aa8c8c696642071a08850 131 Pfam PF07883 Cupin domain 40 98 4.3E-12 T 29-03-2018 IPR013096 Cupin 2, conserved barrel SMALA_RS23920 c47ca280bb8aa8c8c696642071a08850 131 SUPERFAMILY SSF51182 3 111 2.34E-21 T 29-03-2018 IPR011051 RmlC-like cupin domain SMALA_RS23920 c47ca280bb8aa8c8c696642071a08850 131 Gene3D G3DSA:2.60.120.10 1 108 5.0E-18 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SMALA_RS41865 d8efe480d235da69a2d17d63f5286273 212 Gene3D G3DSA:3.40.50.150 8 168 2.4E-27 T 29-03-2018 SMALA_RS41865 d8efe480d235da69a2d17d63f5286273 212 Pfam PF13649 Methyltransferase domain 45 138 2.1E-15 T 29-03-2018 SMALA_RS41865 d8efe480d235da69a2d17d63f5286273 212 SUPERFAMILY SSF53335 9 205 4.82E-36 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS20700 b2ba323bd0f4650a1f4903ff0168c1ef 393 Gene3D G3DSA:3.40.640.10 46 297 1.2E-68 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS20700 b2ba323bd0f4650a1f4903ff0168c1ef 393 Pfam PF00155 Aminotransferase class I and II 33 387 7.5E-67 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMALA_RS20700 b2ba323bd0f4650a1f4903ff0168c1ef 393 SUPERFAMILY SSF53383 8 389 1.73E-109 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS20700 b2ba323bd0f4650a1f4903ff0168c1ef 393 Gene3D G3DSA:3.90.1150.10 298 392 9.3E-19 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS26520 1660df71751f31349e5a8e2448acecb9 132 Pfam PF12680 SnoaL-like domain 10 116 3.1E-15 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain SMALA_RS26520 1660df71751f31349e5a8e2448acecb9 132 SUPERFAMILY SSF54427 3 129 2.07E-31 T 29-03-2018 IPR032710 NTF2-like domain SMALA_RS26520 1660df71751f31349e5a8e2448acecb9 132 Gene3D G3DSA:3.10.450.50 2 131 2.6E-21 T 29-03-2018 SMALA_RS00185 c55cc99a21e4d45e15d186a0a3795eb1 320 Gene3D G3DSA:3.60.10.10 101 318 9.2E-18 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMALA_RS00185 c55cc99a21e4d45e15d186a0a3795eb1 320 SUPERFAMILY SSF56219 105 318 1.03E-21 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMALA_RS00185 c55cc99a21e4d45e15d186a0a3795eb1 320 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 124 310 3.6E-8 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMALA_RS09970 1eec1b9fa3205da9f96d88c021a33e66 136 Pfam PF10825 Protein of unknown function (DUF2752) 47 95 3.9E-17 T 29-03-2018 IPR021215 Protein of unknown function DUF2752 SMALA_RS00875 0e14726d3b54a3cb51cca2840dc547ab 379 Pfam PF01757 Acyltransferase family 31 334 1.7E-17 T 29-03-2018 IPR002656 Acyltransferase 3 GO:0016747 SMALA_RS32050 84709c83ef3e77f28d25e5ca7f47c396 250 Pfam PF00483 Nucleotidyl transferase 3 154 9.9E-11 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 SMALA_RS32050 84709c83ef3e77f28d25e5ca7f47c396 250 Gene3D G3DSA:3.90.550.10 1 248 5.0E-32 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS32050 84709c83ef3e77f28d25e5ca7f47c396 250 SUPERFAMILY SSF53448 1 242 7.43E-33 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS26425 7e4cf80742539e5823fe41d43eb8d62a 350 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 2 60 9.4E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS26425 7e4cf80742539e5823fe41d43eb8d62a 350 Gene3D G3DSA:1.10.10.10 1 79 7.4E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS26425 7e4cf80742539e5823fe41d43eb8d62a 350 Gene3D G3DSA:3.40.190.10 179 264 8.1E-11 T 29-03-2018 SMALA_RS26425 7e4cf80742539e5823fe41d43eb8d62a 350 Gene3D G3DSA:3.40.190.10 80 178 1.0E-13 T 29-03-2018 SMALA_RS26425 7e4cf80742539e5823fe41d43eb8d62a 350 SUPERFAMILY SSF46785 2 102 9.07E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS26425 7e4cf80742539e5823fe41d43eb8d62a 350 SUPERFAMILY SSF53850 91 273 6.83E-17 T 29-03-2018 SMALA_RS26425 7e4cf80742539e5823fe41d43eb8d62a 350 Pfam PF03466 LysR substrate binding domain 89 274 1.3E-20 T 29-03-2018 IPR005119 LysR, substrate-binding SMALA_RS26425 7e4cf80742539e5823fe41d43eb8d62a 350 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 16 27 1.4E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS26425 7e4cf80742539e5823fe41d43eb8d62a 350 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 27 37 1.4E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS26425 7e4cf80742539e5823fe41d43eb8d62a 350 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 37 48 1.4E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS06460 464e6dc2fcd0d0fb1adc27e596512a2d 392 SUPERFAMILY SSF51569 6 389 1.03E-134 T 29-03-2018 SMALA_RS06460 464e6dc2fcd0d0fb1adc27e596512a2d 392 Pfam PF01474 Class-II DAHP synthetase family 7 171 1.5E-43 T 29-03-2018 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 SMALA_RS06460 464e6dc2fcd0d0fb1adc27e596512a2d 392 Pfam PF01474 Class-II DAHP synthetase family 183 387 2.6E-77 T 29-03-2018 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 SMALA_RS08395 ad8c45f7f6fe0fdc965d965a06243c47 248 SUPERFAMILY SSF53335 18 246 6.69E-31 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS08395 ad8c45f7f6fe0fdc965d965a06243c47 248 Pfam PF13847 Methyltransferase domain 36 149 2.9E-14 T 29-03-2018 IPR025714 Methyltransferase domain SMALA_RS08395 ad8c45f7f6fe0fdc965d965a06243c47 248 Gene3D G3DSA:3.40.50.150 1 247 1.6E-31 T 29-03-2018 SMALA_RS39685 bb1bd63ca0d8f441ce09c6b690c2e20b 323 SUPERFAMILY SSF53659 1 319 5.93E-101 T 29-03-2018 SMALA_RS39685 bb1bd63ca0d8f441ce09c6b690c2e20b 323 TIGRFAM TIGR00557 pdxA: 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 1 318 1.5E-105 T 29-03-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 SMALA_RS39685 bb1bd63ca0d8f441ce09c6b690c2e20b 323 Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA 24 314 2.7E-101 T 29-03-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 SMALA_RS39685 bb1bd63ca0d8f441ce09c6b690c2e20b 323 Hamap MF_00536 4-hydroxythreonine-4-phosphate dehydrogenase [pdxA]. 1 318 32.284 T 29-03-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 SMALA_RS39685 bb1bd63ca0d8f441ce09c6b690c2e20b 323 Gene3D G3DSA:3.40.718.10 1 320 2.1E-122 T 29-03-2018 SMALA_RS12485 2a232d0488ceaea5a876a0560eb429fe 281 SUPERFAMILY SSF161098 38 263 3.4E-54 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS12485 2a232d0488ceaea5a876a0560eb429fe 281 Gene3D G3DSA:1.10.3720.10 1 276 6.0E-44 T 29-03-2018 SMALA_RS12485 2a232d0488ceaea5a876a0560eb429fe 281 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 72 268 4.9E-16 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS42725 c8de4afa5f98f1259b5c78f8576c3e4c 405 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 11 391 2.3E-58 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 SMALA_RS42725 c8de4afa5f98f1259b5c78f8576c3e4c 405 SMART SM01329 9 395 2.1E-108 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 SMALA_RS42725 c8de4afa5f98f1259b5c78f8576c3e4c 405 Gene3D G3DSA:3.40.718.10 1 405 6.5E-116 T 29-03-2018 SMALA_RS42725 c8de4afa5f98f1259b5c78f8576c3e4c 405 TIGRFAM TIGR00127 nadp_idh_euk: isocitrate dehydrogenase, NADP-dependent 3 401 8.5E-182 T 29-03-2018 IPR004790 Isocitrate dehydrogenase NADP-dependent GO:0004450|GO:0006102|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 SMALA_RS42725 c8de4afa5f98f1259b5c78f8576c3e4c 405 PIRSF PIRSF000108 1 405 1.9E-195 T 29-03-2018 IPR004790 Isocitrate dehydrogenase NADP-dependent GO:0004450|GO:0006102|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 SMALA_RS42725 c8de4afa5f98f1259b5c78f8576c3e4c 405 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 270 289 - T 29-03-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 SMALA_RS42725 c8de4afa5f98f1259b5c78f8576c3e4c 405 SUPERFAMILY SSF53659 2 400 9.79E-135 T 29-03-2018 SMALA_RS12110 d7bec12392ab3589f311104ecce6e08a 410 Gene3D G3DSA:1.10.3470.10 64 402 3.2E-26 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SMALA_RS12110 d7bec12392ab3589f311104ecce6e08a 410 Pfam PF02653 Branched-chain amino acid transport system / permease component 67 398 2.0E-46 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 SMALA_RS17790 e98104b7193da3f6ddc318f792af0112 690 Gene3D G3DSA:3.30.2010.10 80 177 2.0E-13 T 29-03-2018 SMALA_RS17790 e98104b7193da3f6ddc318f792af0112 690 Pfam PF01435 Peptidase family M48 95 326 6.6E-13 T 29-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 SMALA_RS33320 a85448379c32aa0574b42ac199fe7f4d 151 Pfam PF10756 Bacterial PH domain 68 138 2.7E-16 T 29-03-2018 IPR019692 Protein of unknown function DUF2581 SMALA_RS21000 ca768cf848c61e5613d53d66460f692e 438 Gene3D G3DSA:1.25.40.10 173 423 7.2E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS21000 ca768cf848c61e5613d53d66460f692e 438 SUPERFAMILY SSF48452 327 397 1.63E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS21000 ca768cf848c61e5613d53d66460f692e 438 SUPERFAMILY SSF48452 194 275 1.63E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS31470 af764af42c69e4df531ca98788e3f42d 303 SUPERFAMILY SSF48317 95 229 6.76E-11 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMALA_RS31470 af764af42c69e4df531ca98788e3f42d 303 Pfam PF01569 PAP2 superfamily 128 230 1.1E-10 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMALA_RS31470 af764af42c69e4df531ca98788e3f42d 303 Gene3D G3DSA:1.20.144.10 68 241 1.3E-9 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMALA_RS39585 c476ce4a3c8e44b686d70623d75731f3 256 SUPERFAMILY SSF89155 34 198 4.84E-29 T 29-03-2018 IPR020945 DMSO/Nitrate reductase chaperone SMALA_RS39585 c476ce4a3c8e44b686d70623d75731f3 256 Gene3D G3DSA:1.10.3480.10 23 215 8.9E-32 T 29-03-2018 IPR020945 DMSO/Nitrate reductase chaperone SMALA_RS39585 c476ce4a3c8e44b686d70623d75731f3 256 TIGRFAM TIGR00684 narJ: nitrate reductase molybdenum cofactor assembly chaperone 42 193 3.3E-34 T 29-03-2018 IPR003765 Nitrate reductase chaperone, NarJ GO:0051082|GO:0051131 SMALA_RS39585 c476ce4a3c8e44b686d70623d75731f3 256 Pfam PF02613 Nitrate reductase delta subunit 72 187 7.7E-12 T 29-03-2018 IPR020945 DMSO/Nitrate reductase chaperone SMALA_RS40725 8751a6158c4ff9f4a056599c8f0b7702 235 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 2.8E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS40725 8751a6158c4ff9f4a056599c8f0b7702 235 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 2.8E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS40725 8751a6158c4ff9f4a056599c8f0b7702 235 Gene3D G3DSA:1.10.10.60 2 61 1.4E-20 T 29-03-2018 SMALA_RS40725 8751a6158c4ff9f4a056599c8f0b7702 235 SUPERFAMILY SSF46689 4 83 9.71E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS40725 8751a6158c4ff9f4a056599c8f0b7702 235 Gene3D G3DSA:1.10.357.10 62 193 9.4E-12 T 29-03-2018 SMALA_RS40725 8751a6158c4ff9f4a056599c8f0b7702 235 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 2.8E-13 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS06055 807294a7564e34750b50930e6c2e4d3a 448 Pfam PF13556 PucR C-terminal helix-turn-helix domain 376 431 7.8E-12 T 29-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain SMALA_RS06055 807294a7564e34750b50930e6c2e4d3a 448 Gene3D G3DSA:1.10.10.10 357 436 9.1E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS24865 57041cebda1c8437b59179bebfb5285a 370 Gene3D G3DSA:3.20.20.80 52 327 4.4E-27 T 29-03-2018 SMALA_RS24865 57041cebda1c8437b59179bebfb5285a 370 SUPERFAMILY SSF51445 56 316 7.55E-18 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS12300 e36b4a16c0f5ad0c76ba207040f185b3 122 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 85 119 7.2E-6 T 29-03-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 SMALA_RS12300 e36b4a16c0f5ad0c76ba207040f185b3 122 SUPERFAMILY SSF57716 87 120 2.85E-6 T 29-03-2018 SMALA_RS11145 a125352e9405faa97e7ae6bfb46dad31 300 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 63 284 1.7E-22 T 29-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 SMALA_RS11145 a125352e9405faa97e7ae6bfb46dad31 300 Gene3D G3DSA:3.20.20.190 45 288 1.4E-44 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 SMALA_RS11145 a125352e9405faa97e7ae6bfb46dad31 300 SUPERFAMILY SSF51695 59 286 1.57E-41 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 SMALA_RS34560 d1f539057d9aefbcf6273b8424ea212a 727 Pfam PF16874 Glycosyl hydrolase family 36 C-terminal domain 629 721 4.5E-8 T 29-03-2018 IPR031705 Glycosyl hydrolase family 36, C-terminal KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 SMALA_RS34560 d1f539057d9aefbcf6273b8424ea212a 727 Pfam PF16875 Glycosyl hydrolase family 36 N-terminal domain 27 268 8.8E-38 T 29-03-2018 IPR031704 Glycosyl hydrolase family 36, N-terminal KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 SMALA_RS34560 d1f539057d9aefbcf6273b8424ea212a 727 Pfam PF02065 Melibiase 273 612 6.3E-114 T 29-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 SMALA_RS34560 d1f539057d9aefbcf6273b8424ea212a 727 PRINTS PR00743 Glycosyl hydrolase family 36 signature 221 236 7.3E-41 T 29-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 SMALA_RS34560 d1f539057d9aefbcf6273b8424ea212a 727 PRINTS PR00743 Glycosyl hydrolase family 36 signature 389 411 7.3E-41 T 29-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 SMALA_RS34560 d1f539057d9aefbcf6273b8424ea212a 727 PRINTS PR00743 Glycosyl hydrolase family 36 signature 522 538 7.3E-41 T 29-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 SMALA_RS34560 d1f539057d9aefbcf6273b8424ea212a 727 PRINTS PR00743 Glycosyl hydrolase family 36 signature 311 325 7.3E-41 T 29-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 SMALA_RS34560 d1f539057d9aefbcf6273b8424ea212a 727 PRINTS PR00743 Glycosyl hydrolase family 36 signature 339 354 7.3E-41 T 29-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 SMALA_RS34560 d1f539057d9aefbcf6273b8424ea212a 727 PRINTS PR00743 Glycosyl hydrolase family 36 signature 447 462 7.3E-41 T 29-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 SMALA_RS34560 d1f539057d9aefbcf6273b8424ea212a 727 PRINTS PR00743 Glycosyl hydrolase family 36 signature 497 513 7.3E-41 T 29-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 SMALA_RS34560 d1f539057d9aefbcf6273b8424ea212a 727 PIRSF PIRSF005536 47 681 5.8E-165 T 29-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 SMALA_RS34560 d1f539057d9aefbcf6273b8424ea212a 727 Gene3D G3DSA:2.60.40.1180 610 727 9.2E-16 T 29-03-2018 SMALA_RS34560 d1f539057d9aefbcf6273b8424ea212a 727 SUPERFAMILY SSF51445 309 639 1.96E-95 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS34560 d1f539057d9aefbcf6273b8424ea212a 727 Gene3D G3DSA:2.70.98.60 3 292 2.3E-57 T 29-03-2018 SMALA_RS34560 d1f539057d9aefbcf6273b8424ea212a 727 Gene3D G3DSA:3.20.20.70 293 609 4.3E-53 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS00310 574923d11c1ae07bbaf7ea33efe64153 272 Pfam PF04072 Leucine carboxyl methyltransferase 20 175 2.3E-21 T 29-03-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 SMALA_RS00310 574923d11c1ae07bbaf7ea33efe64153 272 Gene3D G3DSA:3.40.50.150 7 264 1.8E-43 T 29-03-2018 SMALA_RS00310 574923d11c1ae07bbaf7ea33efe64153 272 SUPERFAMILY SSF53335 12 239 1.4E-62 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS00310 574923d11c1ae07bbaf7ea33efe64153 272 PIRSF PIRSF028177 1 272 3.3E-84 T 29-03-2018 IPR016874 Tetracenomycin polyketide synthesis O-methyltransferase TcmP GO:0017000|GO:1901106 SMALA_RS23330 64f205987ef275342274dcf3ae613ec1 383 TIGRFAM TIGR02772 Ku_bact: Ku protein 1 255 1.4E-83 T 29-03-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type SMALA_RS23330 64f205987ef275342274dcf3ae613ec1 383 SMART SM00559 52 181 9.1E-35 T 29-03-2018 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571|Reactome: R-HSA-6798695 SMALA_RS23330 64f205987ef275342274dcf3ae613ec1 383 Hamap MF_01875 Non-homologous end joining protein Ku [ku]. 1 253 29.84 T 29-03-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type SMALA_RS23330 64f205987ef275342274dcf3ae613ec1 383 Gene3D G3DSA:2.40.290.10 1 180 1.4E-28 T 29-03-2018 IPR016194 SPOC-like, C-terminal domain SMALA_RS23330 64f205987ef275342274dcf3ae613ec1 383 PIRSF PIRSF006493 1 294 9.7E-75 T 29-03-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type SMALA_RS23330 64f205987ef275342274dcf3ae613ec1 383 PIRSF PIRSF006493 283 383 4000.0 T 29-03-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type SMALA_RS23330 64f205987ef275342274dcf3ae613ec1 383 SUPERFAMILY SSF100939 1 253 3.73E-44 T 29-03-2018 IPR016194 SPOC-like, C-terminal domain SMALA_RS23330 64f205987ef275342274dcf3ae613ec1 383 Pfam PF02735 Ku70/Ku80 beta-barrel domain 11 188 3.3E-30 T 29-03-2018 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571|Reactome: R-HSA-6798695 SMALA_RS08110 4e83e71f2882b553385241f71bb76126 217 SUPERFAMILY SSF51735 1 197 1.83E-37 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS08110 4e83e71f2882b553385241f71bb76126 217 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 2 95 3.9E-15 T 29-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal SMALA_RS08110 4e83e71f2882b553385241f71bb76126 217 Gene3D G3DSA:3.40.50.720 1 205 4.4E-25 T 29-03-2018 SMALA_RS33440 34874a53fd611d494de4deace4cabdfd 439 Pfam PF00067 Cytochrome P450 224 410 6.3E-21 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS33440 34874a53fd611d494de4deace4cabdfd 439 PRINTS PR00359 B-class P450 signature 127 138 3.5E-43 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS33440 34874a53fd611d494de4deace4cabdfd 439 PRINTS PR00359 B-class P450 signature 191 206 3.5E-43 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS33440 34874a53fd611d494de4deace4cabdfd 439 PRINTS PR00359 B-class P450 signature 331 358 3.5E-43 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS33440 34874a53fd611d494de4deace4cabdfd 439 PRINTS PR00359 B-class P450 signature 380 389 3.5E-43 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS33440 34874a53fd611d494de4deace4cabdfd 439 PRINTS PR00359 B-class P450 signature 234 256 3.5E-43 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS33440 34874a53fd611d494de4deace4cabdfd 439 PRINTS PR00359 B-class P450 signature 174 190 3.5E-43 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS33440 34874a53fd611d494de4deace4cabdfd 439 PRINTS PR00359 B-class P450 signature 389 400 3.5E-43 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS33440 34874a53fd611d494de4deace4cabdfd 439 PRINTS PR00359 B-class P450 signature 314 325 3.5E-43 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS33440 34874a53fd611d494de4deace4cabdfd 439 PRINTS PR00359 B-class P450 signature 359 374 3.5E-43 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS33440 34874a53fd611d494de4deace4cabdfd 439 SUPERFAMILY SSF48264 35 436 1.19E-85 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS33440 34874a53fd611d494de4deace4cabdfd 439 PRINTS PR00385 P450 superfamily signature 389 400 1.8E-6 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS33440 34874a53fd611d494de4deace4cabdfd 439 PRINTS PR00385 P450 superfamily signature 314 325 1.8E-6 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS33440 34874a53fd611d494de4deace4cabdfd 439 PRINTS PR00385 P450 superfamily signature 380 389 1.8E-6 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS33440 34874a53fd611d494de4deace4cabdfd 439 PRINTS PR00385 P450 superfamily signature 279 296 1.8E-6 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS33440 34874a53fd611d494de4deace4cabdfd 439 Gene3D G3DSA:1.10.630.10 19 438 8.1E-71 T 29-03-2018 SMALA_RS43185 773e5cf843cd731ff1e4976060cde5f2 565 Pfam PF12696 TraM recognition site of TraD and TraG 393 508 2.2E-21 T 29-03-2018 IPR032689 TraD/TraG, TraM recognition site SMALA_RS43185 773e5cf843cd731ff1e4976060cde5f2 565 Gene3D G3DSA:3.40.50.300 79 541 1.3E-21 T 29-03-2018 SMALA_RS43185 773e5cf843cd731ff1e4976060cde5f2 565 SUPERFAMILY SSF52540 114 535 5.01E-26 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS29790 6f69647ccaa1305dba3fb360049b6aa6 262 SUPERFAMILY SSF52540 8 225 3.15E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS29790 6f69647ccaa1305dba3fb360049b6aa6 262 Pfam PF00005 ABC transporter 25 175 1.7E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS29790 6f69647ccaa1305dba3fb360049b6aa6 262 Gene3D G3DSA:3.40.50.300 6 259 4.2E-55 T 29-03-2018 SMALA_RS29790 6f69647ccaa1305dba3fb360049b6aa6 262 SMART SM00382 34 223 2.5E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS07830 37f48e17a015b66c6eb2aa7afedb70a5 103 Gene3D G3DSA:1.10.287.1060 4 102 6.7E-5 T 29-03-2018 SMALA_RS15035 909272905ad48475f287360e05d3feaf 250 SMART SM00849 18 199 4.2E-7 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS15035 909272905ad48475f287360e05d3feaf 250 Gene3D G3DSA:3.60.15.10 1 250 1.6E-47 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS15035 909272905ad48475f287360e05d3feaf 250 SUPERFAMILY SSF56281 1 249 1.26E-52 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS15035 909272905ad48475f287360e05d3feaf 250 Pfam PF12706 Beta-lactamase superfamily domain 30 218 3.3E-21 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS02320 8c68e8ececc4e9e6d8306f795f3190bb 242 Pfam PF09859 Oxygenase, catalysing oxidative methylation of damaged DNA 70 241 1.3E-78 T 29-03-2018 IPR018655 Protein of unknown function DUF2086 SMALA_RS02320 8c68e8ececc4e9e6d8306f795f3190bb 242 Gene3D G3DSA:2.60.120.620 19 242 5.1E-20 T 29-03-2018 SMALA_RS26185 49a4536b6092f047411b549cf90db72c 284 Pfam PF08281 Sigma-70, region 4 201 251 9.2E-14 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS26185 49a4536b6092f047411b549cf90db72c 284 Pfam PF04542 Sigma-70 region 2 95 159 3.2E-17 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS26185 49a4536b6092f047411b549cf90db72c 284 Gene3D G3DSA:1.10.1740.10 76 156 4.2E-22 T 29-03-2018 SMALA_RS26185 49a4536b6092f047411b549cf90db72c 284 SUPERFAMILY SSF88946 73 174 3.41E-23 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS26185 49a4536b6092f047411b549cf90db72c 284 Gene3D G3DSA:1.10.10.10 157 258 7.5E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS26185 49a4536b6092f047411b549cf90db72c 284 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 94 253 1.5E-25 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS26185 49a4536b6092f047411b549cf90db72c 284 TIGRFAM TIGR02947 SigH_actino: RNA polymerase sigma-70 factor, TIGR02947 family 79 266 7.7E-107 T 29-03-2018 IPR014293 RNA polymerase sigma-70, actinobacteria GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS26185 49a4536b6092f047411b549cf90db72c 284 SUPERFAMILY SSF88659 194 256 7.48E-16 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMALA_RS08980 ab6a4184b549c2e99e08938081c7ab2b 154 Gene3D G3DSA:3.30.565.10 1 147 8.6E-12 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS08980 ab6a4184b549c2e99e08938081c7ab2b 154 Pfam PF13581 Histidine kinase-like ATPase domain 7 129 1.6E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS29270 4b93913ac9eadd225f67f894ed827fb9 118 Pfam PF05331 Protein of unknown function (DUF742) 6 116 1.2E-36 T 29-03-2018 IPR007995 Protein of unknown function DUF742 SMALA_RS29270 4b93913ac9eadd225f67f894ed827fb9 118 Gene3D G3DSA:1.10.10.10 20 117 4.5E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS34515 3a6b159e10b5761676cae2c022011b91 320 Pfam PF05726 Pirin C-terminal cupin domain 192 291 4.6E-18 T 29-03-2018 IPR008778 Pirin, C-terminal domain Reactome: R-HSA-8935690 SMALA_RS34515 3a6b159e10b5761676cae2c022011b91 320 Gene3D G3DSA:2.60.120.10 18 265 8.4E-58 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SMALA_RS34515 3a6b159e10b5761676cae2c022011b91 320 SUPERFAMILY SSF51182 29 301 2.54E-66 T 29-03-2018 IPR011051 RmlC-like cupin domain SMALA_RS34515 3a6b159e10b5761676cae2c022011b91 320 Pfam PF02678 Pirin 45 140 1.3E-23 T 29-03-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 SMALA_RS34515 3a6b159e10b5761676cae2c022011b91 320 PIRSF PIRSF006232 20 301 4.7E-75 T 29-03-2018 IPR012093 Pirin Reactome: R-HSA-8935690 SMALA_RS40305 acbce65ade29e03699d458df46847af7 319 Pfam PF00146 NADH dehydrogenase 14 308 3.1E-37 T 29-03-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS07550 3f7efd21e4f6cb0598883cc98836a2f5 202 SUPERFAMILY SSF55729 7 174 5.21E-36 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS07550 3f7efd21e4f6cb0598883cc98836a2f5 202 Gene3D G3DSA:3.40.630.30 4 182 1.5E-26 T 29-03-2018 SMALA_RS07550 3f7efd21e4f6cb0598883cc98836a2f5 202 Pfam PF13302 Acetyltransferase (GNAT) domain 12 150 2.0E-22 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SMALA_RS22105 dfa1d0198ba28cb36939c440d4a91fbf 119 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 19 118 3.9E-36 T 29-03-2018 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS22105 dfa1d0198ba28cb36939c440d4a91fbf 119 Hamap MF_01394 NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic [ndhC]. 1 119 17.732 T 29-03-2018 IPR023043 NAD(P)H-quinone oxidoreductase subunit 3, bacterial/plastid GO:0016651|GO:0055114 SMALA_RS25060 81464c989fcd361dcb5dcc73c80d8dfa 60 Pfam PF13359 DDE superfamily endonuclease 9 55 1.2E-5 T 29-03-2018 IPR027806 Harbinger transposase-derived nuclease domain SMALA_RS09240 facb4fbd6485db0850f1eb2e809dd157 186 TIGRFAM TIGR02406 ectoine_EctA: diaminobutyrate acetyltransferase 21 176 9.3E-65 T 29-03-2018 IPR012772 L-2,4-diaminobutyric acid acetyltransferase GO:0019491|GO:0033816 KEGG: 00250+2.3.1.17|KEGG: 00260+2.3.1.178 SMALA_RS09240 facb4fbd6485db0850f1eb2e809dd157 186 Gene3D G3DSA:3.40.630.30 18 180 1.8E-30 T 29-03-2018 SMALA_RS09240 facb4fbd6485db0850f1eb2e809dd157 186 SUPERFAMILY SSF55729 15 140 1.62E-19 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS09240 facb4fbd6485db0850f1eb2e809dd157 186 Pfam PF00583 Acetyltransferase (GNAT) family 50 140 2.7E-13 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SMALA_RS35340 f390a97b5dae5059851f21d673204262 314 Gene3D G3DSA:3.40.190.10 181 295 4.1E-7 T 29-03-2018 SMALA_RS35340 f390a97b5dae5059851f21d673204262 314 Gene3D G3DSA:3.40.190.10 60 180 9.9E-17 T 29-03-2018 SMALA_RS35340 f390a97b5dae5059851f21d673204262 314 SUPERFAMILY SSF53850 61 293 9.19E-31 T 29-03-2018 SMALA_RS35340 f390a97b5dae5059851f21d673204262 314 SMART SM00062 64 295 7.0E-15 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SMALA_RS35340 f390a97b5dae5059851f21d673204262 314 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 65 292 1.4E-29 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SMALA_RS17540 b79e229108bd45e001cad7e9e95e19d9 426 SUPERFAMILY SSF53850 50 419 4.84E-63 T 29-03-2018 SMALA_RS17540 b79e229108bd45e001cad7e9e95e19d9 426 Gene3D G3DSA:3.40.190.10 148 424 2.5E-40 T 29-03-2018 SMALA_RS17540 b79e229108bd45e001cad7e9e95e19d9 426 Pfam PF01547 Bacterial extracellular solute-binding protein 54 336 3.1E-32 T 29-03-2018 IPR006059 Solute-binding family 1 GO:0006810 SMALA_RS23270 940298616270a71ea6fbf91f12f7aa5a 249 Gene3D G3DSA:1.10.3630.10 2 199 1.8E-40 T 29-03-2018 SMALA_RS23270 940298616270a71ea6fbf91f12f7aa5a 249 Pfam PF05719 Golgi phosphoprotein 3 (GPP34) 8 202 7.2E-47 T 29-03-2018 IPR008628 Golgi phosphoprotein 3-like GO:0070273 SMALA_RS08790 55c107c6044f02e9d799f21fd54cf19b 470 PIRSF PIRSF033563 205 469 1.1E-58 T 29-03-2018 IPR008323 Uncharacterised conserved protein UCP033563 SMALA_RS08790 55c107c6044f02e9d799f21fd54cf19b 470 PIRSF PIRSF033563 10 171 3.7E-44 T 29-03-2018 IPR008323 Uncharacterised conserved protein UCP033563 SMALA_RS08790 55c107c6044f02e9d799f21fd54cf19b 470 Pfam PF06245 Protein of unknown function (DUF1015) 13 161 7.3E-46 T 29-03-2018 IPR008323 Uncharacterised conserved protein UCP033563 SMALA_RS08790 55c107c6044f02e9d799f21fd54cf19b 470 Pfam PF06245 Protein of unknown function (DUF1015) 207 465 6.0E-63 T 29-03-2018 IPR008323 Uncharacterised conserved protein UCP033563 SMALA_RS04810 2c6d4ea1bd6eea098ca36ad37d21421a 141 Pfam PF03928 Haem-degrading 11 137 3.6E-31 T 29-03-2018 IPR005624 Haem-degrading SMALA_RS04810 2c6d4ea1bd6eea098ca36ad37d21421a 141 Gene3D G3DSA:3.30.450.20 2 123 1.3E-5 T 29-03-2018 SMALA_RS04810 2c6d4ea1bd6eea098ca36ad37d21421a 141 SUPERFAMILY SSF143744 7 140 5.89E-36 T 29-03-2018 SMALA_RS21585 aef346c826a8e49959cb46efc1e921d3 144 SUPERFAMILY SSF55874 44 135 6.86E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS21585 aef346c826a8e49959cb46efc1e921d3 144 Gene3D G3DSA:3.30.565.10 8 144 7.8E-12 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS21585 aef346c826a8e49959cb46efc1e921d3 144 Pfam PF13581 Histidine kinase-like ATPase domain 24 130 6.4E-9 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS42485 a7e8e868bf44f87ea6678ec64fdfea86 210 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 2 208 24.554 T 29-03-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 SMALA_RS42485 a7e8e868bf44f87ea6678ec64fdfea86 210 SUPERFAMILY SSF52218 3 204 7.33E-33 T 29-03-2018 IPR029039 Flavoprotein-like domain SMALA_RS42485 a7e8e868bf44f87ea6678ec64fdfea86 210 Gene3D G3DSA:3.40.50.360 1 210 5.3E-30 T 29-03-2018 IPR029039 Flavoprotein-like domain SMALA_RS42485 a7e8e868bf44f87ea6678ec64fdfea86 210 Pfam PF02525 Flavodoxin-like fold 4 158 2.4E-25 T 29-03-2018 IPR003680 Flavodoxin-like fold SMALA_RS11360 1e282933251550bcc4b4903b574b5829 344 SUPERFAMILY SSF53807 72 338 9.03E-62 T 29-03-2018 SMALA_RS11360 1e282933251550bcc4b4903b574b5829 344 Gene3D G3DSA:3.40.50.1980 66 176 3.9E-25 T 29-03-2018 SMALA_RS11360 1e282933251550bcc4b4903b574b5829 344 Gene3D G3DSA:3.40.50.1980 180 343 6.1E-32 T 29-03-2018 SMALA_RS11360 1e282933251550bcc4b4903b574b5829 344 Pfam PF01497 Periplasmic binding protein 92 314 3.0E-28 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 SMALA_RS41260 b171011a2746e7c4ab89d8fe6dfb81a5 297 Pfam PF06719 AraC-type transcriptional regulator N-terminus 24 173 3.3E-42 T 29-03-2018 IPR009594 Transcription regulator HTH, AraC, N-terminal SMALA_RS41260 b171011a2746e7c4ab89d8fe6dfb81a5 297 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 254 269 7.2E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SMALA_RS41260 b171011a2746e7c4ab89d8fe6dfb81a5 297 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 269 285 7.2E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SMALA_RS41260 b171011a2746e7c4ab89d8fe6dfb81a5 297 Pfam PF12833 Helix-turn-helix domain 208 283 2.5E-20 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS41260 b171011a2746e7c4ab89d8fe6dfb81a5 297 Gene3D G3DSA:1.10.10.60 242 294 7.5E-13 T 29-03-2018 SMALA_RS41260 b171011a2746e7c4ab89d8fe6dfb81a5 297 SUPERFAMILY SSF46689 187 236 3.76E-10 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS41260 b171011a2746e7c4ab89d8fe6dfb81a5 297 SMART SM00342 202 285 1.9E-26 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMALA_RS41260 b171011a2746e7c4ab89d8fe6dfb81a5 297 SUPERFAMILY SSF46689 238 286 8.96E-10 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS41260 b171011a2746e7c4ab89d8fe6dfb81a5 297 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 239 281 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 SMALA_RS41260 b171011a2746e7c4ab89d8fe6dfb81a5 297 Gene3D G3DSA:1.10.10.60 139 241 1.2E-15 T 29-03-2018 SMALA_RS42105 b3b28b984dd2718324087bbca1919ce8 125 SUPERFAMILY SSF51182 36 111 2.93E-16 T 29-03-2018 IPR011051 RmlC-like cupin domain SMALA_RS42105 b3b28b984dd2718324087bbca1919ce8 125 Gene3D G3DSA:2.60.120.10 5 119 9.4E-17 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SMALA_RS42105 b3b28b984dd2718324087bbca1919ce8 125 Pfam PF07883 Cupin domain 44 109 4.3E-13 T 29-03-2018 IPR013096 Cupin 2, conserved barrel SMALA_RS25805 7cfe889d18ae5be0dad91fe403c6eed2 55 Pfam PF11314 Protein of unknown function (DUF3117) 4 53 3.0E-29 T 29-03-2018 IPR021465 Protein of unknown function DUF3117 SMALA_RS33935 f8afb07e009cdfd15eb52fd6ed6043f0 244 SUPERFAMILY SSF88713 45 230 5.68E-57 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 SMALA_RS33935 f8afb07e009cdfd15eb52fd6ed6043f0 244 Pfam PF01522 Polysaccharide deacetylase 51 168 6.1E-30 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 SMALA_RS33935 f8afb07e009cdfd15eb52fd6ed6043f0 244 Gene3D G3DSA:3.20.20.370 32 235 1.5E-45 T 29-03-2018 SMALA_RS40315 61543cb6e4e47b858a532e203561842b 532 Pfam PF00361 Proton-conducting membrane transporter 171 457 1.9E-44 T 29-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS40315 61543cb6e4e47b858a532e203561842b 532 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 425 451 2.4E-6 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS40315 61543cb6e4e47b858a532e203561842b 532 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 284 308 2.4E-6 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS40315 61543cb6e4e47b858a532e203561842b 532 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 373 392 2.4E-6 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS16555 bfba3f36df5ffd3c033ae15185350c34 325 Gene3D G3DSA:3.90.550.10 1 299 5.0E-46 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS16555 bfba3f36df5ffd3c033ae15185350c34 325 Pfam PF00535 Glycosyl transferase family 2 5 134 9.0E-35 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 SMALA_RS16555 bfba3f36df5ffd3c033ae15185350c34 325 SUPERFAMILY SSF53448 3 232 3.21E-48 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS16760 6aa987929335045875d1e139d1bb6f60 423 Pfam PF00464 Serine hydroxymethyltransferase 11 386 9.6E-152 T 29-03-2018 SMALA_RS16760 6aa987929335045875d1e139d1bb6f60 423 PIRSF PIRSF000412 2 422 9.0E-162 T 29-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 SMALA_RS16760 6aa987929335045875d1e139d1bb6f60 423 Gene3D G3DSA:3.90.1150.10 275 418 8.7E-58 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS16760 6aa987929335045875d1e139d1bb6f60 423 SUPERFAMILY SSF53383 9 419 3.62E-163 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS16760 6aa987929335045875d1e139d1bb6f60 423 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 9 419 48.868 T 29-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 SMALA_RS16760 6aa987929335045875d1e139d1bb6f60 423 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 224 240 - T 29-03-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 SMALA_RS16760 6aa987929335045875d1e139d1bb6f60 423 Gene3D G3DSA:3.40.640.10 39 274 1.0E-50 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS32175 0608e5f854ce00b17b882b585c2e71eb 456 Pfam PF04055 Radical SAM superfamily 52 223 1.3E-14 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 SMALA_RS32175 0608e5f854ce00b17b882b585c2e71eb 456 Gene3D G3DSA:3.20.20.70 30 417 8.5E-34 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS32175 0608e5f854ce00b17b882b585c2e71eb 456 SUPERFAMILY SSF102114 9 442 1.83E-70 T 29-03-2018 SMALA_RS32175 0608e5f854ce00b17b882b585c2e71eb 456 SMART SM00729 46 265 2.0E-35 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 SMALA_RS20185 959b9ee0541e6afe2bfa4ad7cbf0cbe6 345 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 2 65 3.4E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS20185 959b9ee0541e6afe2bfa4ad7cbf0cbe6 345 SUPERFAMILY SSF46785 2 99 5.44E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS20185 959b9ee0541e6afe2bfa4ad7cbf0cbe6 345 Gene3D G3DSA:1.10.10.10 1 93 1.7E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS32205 16e1bc42c21a8ba4efd76a7ce8e98302 263 SUPERFAMILY SSF53955 60 263 2.47E-71 T 29-03-2018 IPR023346 Lysozyme-like domain SMALA_RS32205 16e1bc42c21a8ba4efd76a7ce8e98302 263 PIRSF PIRSF001060 2 263 1.8E-88 T 29-03-2018 IPR016283 Glycoside hydrolase, family 19 GO:0004568|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 SMALA_RS32205 16e1bc42c21a8ba4efd76a7ce8e98302 263 Pfam PF00182 Chitinase class I 61 263 1.2E-46 T 29-03-2018 IPR000726 Glycoside hydrolase, family 19, catalytic GO:0004568|GO:0006032|GO:0016998 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 SMALA_RS32205 16e1bc42c21a8ba4efd76a7ce8e98302 263 Gene3D G3DSA:1.10.530.10 56 263 8.0E-68 T 29-03-2018 SMALA_RS37895 21b4b3947d395a85b3b5378856433635 426 Pfam PF04143 Sulphur transport 77 406 2.0E-63 T 29-03-2018 IPR007272 Sulphur transport domain SMALA_RS39710 2bbff1a82c79d54f81377ea2b4d89c63 67 SUPERFAMILY SSF54862 2 62 5.59E-15 T 29-03-2018 SMALA_RS39710 2bbff1a82c79d54f81377ea2b4d89c63 67 PRINTS PR00352 3Fe-4S ferredoxin signature 48 60 6.7E-7 T 29-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 SMALA_RS39710 2bbff1a82c79d54f81377ea2b4d89c63 67 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 6.7E-7 T 29-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 SMALA_RS39710 2bbff1a82c79d54f81377ea2b4d89c63 67 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 6.7E-7 T 29-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 SMALA_RS39710 2bbff1a82c79d54f81377ea2b4d89c63 67 Gene3D G3DSA:3.30.70.20 1 65 8.7E-10 T 29-03-2018 SMALA_RS39710 2bbff1a82c79d54f81377ea2b4d89c63 67 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 5 61 9.2E-14 T 29-03-2018 SMALA_RS05710 b3a35b31c73e86415df931c5335eff50 341 Pfam PF13377 Periplasmic binding protein-like domain 173 324 1.3E-18 T 29-03-2018 SMALA_RS05710 b3a35b31c73e86415df931c5335eff50 341 Gene3D G3DSA:1.10.260.40 1 54 3.0E-16 T 29-03-2018 SMALA_RS05710 b3a35b31c73e86415df931c5335eff50 341 SUPERFAMILY SSF53822 74 320 2.36E-26 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SMALA_RS05710 b3a35b31c73e86415df931c5335eff50 341 SMART SM00354 1 70 2.2E-8 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS05710 b3a35b31c73e86415df931c5335eff50 341 Gene3D G3DSA:3.40.50.2300 177 319 1.3E-21 T 29-03-2018 SMALA_RS05710 b3a35b31c73e86415df931c5335eff50 341 SUPERFAMILY SSF47413 1 57 1.13E-10 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS05710 b3a35b31c73e86415df931c5335eff50 341 Pfam PF00356 Bacterial regulatory proteins, lacI family 1 45 9.7E-12 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS05710 b3a35b31c73e86415df931c5335eff50 341 Gene3D G3DSA:3.40.50.2300 55 176 4.9E-24 T 29-03-2018 SMALA_RS30385 9244fd3d5b148b1a6f3c5c29d5ee5222 351 Gene3D G3DSA:1.25.40.10 13 215 2.6E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS30385 9244fd3d5b148b1a6f3c5c29d5ee5222 351 Gene3D G3DSA:1.25.40.10 220 326 1.8E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS16015 144fecd3b4bf59749d0bdddee85e5135 169 SUPERFAMILY SSF55874 73 165 2.26E-10 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS16015 144fecd3b4bf59749d0bdddee85e5135 169 Gene3D G3DSA:3.30.565.10 35 169 5.2E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS16015 144fecd3b4bf59749d0bdddee85e5135 169 Pfam PF13581 Histidine kinase-like ATPase domain 48 162 5.3E-10 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS37985 121accf4c94df1632de61247bbe139aa 343 SUPERFAMILY SSF53822 102 323 2.03E-27 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SMALA_RS37985 121accf4c94df1632de61247bbe139aa 343 Pfam PF13407 Periplasmic binding protein domain 104 295 3.9E-25 T 29-03-2018 IPR025997 Periplasmic binding protein SMALA_RS37985 121accf4c94df1632de61247bbe139aa 343 SMART SM00354 4 71 1.4E-5 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS37985 121accf4c94df1632de61247bbe139aa 343 Gene3D G3DSA:3.40.50.2300 181 317 8.0E-11 T 29-03-2018 SMALA_RS37985 121accf4c94df1632de61247bbe139aa 343 Pfam PF00356 Bacterial regulatory proteins, lacI family 7 46 6.8E-9 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMALA_RS37985 121accf4c94df1632de61247bbe139aa 343 Gene3D G3DSA:3.40.50.2300 69 180 1.7E-13 T 29-03-2018 SMALA_RS37985 121accf4c94df1632de61247bbe139aa 343 Gene3D G3DSA:1.10.260.40 6 68 5.5E-13 T 29-03-2018 SMALA_RS37985 121accf4c94df1632de61247bbe139aa 343 SUPERFAMILY SSF47413 6 47 9.09E-9 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS29900 0ef6af693e670eaedbcd76590a2c5162 268 TIGRFAM TIGR04222 near_uncomplex: TIGR04222 domain 9 253 1.5E-40 T 29-03-2018 IPR026467 Ser/Gly rich, Cys interspersed, C-terminal domain SMALA_RS40670 8c8580eec26e9f61d1119a93c06b6329 333 SUPERFAMILY SSF53850 5 137 7.25E-21 T 29-03-2018 SMALA_RS40670 8c8580eec26e9f61d1119a93c06b6329 333 SUPERFAMILY SSF53850 167 325 7.25E-21 T 29-03-2018 SMALA_RS40670 8c8580eec26e9f61d1119a93c06b6329 333 Gene3D G3DSA:3.40.190.10 85 217 1.5E-18 T 29-03-2018 SMALA_RS26720 074bded622b68cdefbdac020e0644998 509 Gene3D G3DSA:3.40.50.150 30 304 9.8E-29 T 29-03-2018 SMALA_RS26720 074bded622b68cdefbdac020e0644998 509 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 62 76 8.2E-18 T 29-03-2018 SMALA_RS26720 074bded622b68cdefbdac020e0644998 509 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 149 161 8.2E-18 T 29-03-2018 SMALA_RS26720 074bded622b68cdefbdac020e0644998 509 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 36 52 8.2E-18 T 29-03-2018 SMALA_RS26720 074bded622b68cdefbdac020e0644998 509 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 180 204 8.2E-18 T 29-03-2018 SMALA_RS26720 074bded622b68cdefbdac020e0644998 509 Gene3D G3DSA:3.90.220.10 315 483 5.0E-4 T 29-03-2018 SMALA_RS26720 074bded622b68cdefbdac020e0644998 509 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 152 158 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 SMALA_RS26720 074bded622b68cdefbdac020e0644998 509 SUPERFAMILY SSF53335 28 271 1.06E-34 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS26720 074bded622b68cdefbdac020e0644998 509 Pfam PF07669 Eco57I restriction-modification methylase 149 245 4.3E-11 T 29-03-2018 IPR011639 Restriction modification methylase Eco57I GO:0003677|GO:0003824|GO:0006304 SMALA_RS41375 2e8bf554ff46ca1ae77d863b2ccb964b 244 Pfam PF06197 Protein of unknown function (DUF998) 27 225 9.9E-18 T 29-03-2018 IPR009339 Protein of unknown function DUF998 SMALA_RS32180 984d537eb17a207e0857c8f8d41771bd 267 Pfam PF00884 Sulfatase 10 242 4.6E-11 T 29-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 SMALA_RS32180 984d537eb17a207e0857c8f8d41771bd 267 Gene3D G3DSA:3.40.720.10 7 260 7.4E-24 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 SMALA_RS32180 984d537eb17a207e0857c8f8d41771bd 267 SUPERFAMILY SSF53649 10 259 6.54E-24 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 SMALA_RS21565 3430aa72947a97695334ff1082a6a70e 377 Gene3D G3DSA:3.20.20.70 1 373 9.4E-105 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS21565 3430aa72947a97695334ff1082a6a70e 377 SUPERFAMILY SSF51395 12 362 1.05E-96 T 29-03-2018 SMALA_RS21565 3430aa72947a97695334ff1082a6a70e 377 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 16 363 3.5E-63 T 29-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 SMALA_RS01685 595cf2cca2523d09886450f51f1adeaf 271 Pfam PF13489 Methyltransferase domain 87 204 4.0E-9 T 29-03-2018 SMALA_RS01685 595cf2cca2523d09886450f51f1adeaf 271 SUPERFAMILY SSF53335 23 270 2.46E-22 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS01685 595cf2cca2523d09886450f51f1adeaf 271 Gene3D G3DSA:3.40.50.150 12 270 4.3E-25 T 29-03-2018 SMALA_RS27450 39046814882546459dcbb1c866fff511 167 Gene3D G3DSA:3.30.565.10 40 167 2.7E-14 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS27450 39046814882546459dcbb1c866fff511 167 Pfam PF13581 Histidine kinase-like ATPase domain 47 146 2.0E-11 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS27450 39046814882546459dcbb1c866fff511 167 SUPERFAMILY SSF55874 62 153 8.46E-10 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS18135 16e375a94d7c15db16f952d288dd16b3 532 SUPERFAMILY SSF56601 150 530 5.31E-64 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMALA_RS18135 16e375a94d7c15db16f952d288dd16b3 532 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 405 419 1.8E-23 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 SMALA_RS18135 16e375a94d7c15db16f952d288dd16b3 532 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 184 203 1.8E-23 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 SMALA_RS18135 16e375a94d7c15db16f952d288dd16b3 532 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 420 434 1.8E-23 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 SMALA_RS18135 16e375a94d7c15db16f952d288dd16b3 532 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 348 370 1.8E-23 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 SMALA_RS18135 16e375a94d7c15db16f952d288dd16b3 532 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 485 498 1.8E-23 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 SMALA_RS18135 16e375a94d7c15db16f952d288dd16b3 532 Gene3D G3DSA:3.40.710.10 146 531 7.4E-41 T 29-03-2018 SMALA_RS18135 16e375a94d7c15db16f952d288dd16b3 532 TIGRFAM TIGR00666 PBP4: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase 312 508 2.6E-48 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 SMALA_RS18135 16e375a94d7c15db16f952d288dd16b3 532 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 310 525 1.8E-59 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 SMALA_RS18135 16e375a94d7c15db16f952d288dd16b3 532 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 146 282 4.9E-23 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 SMALA_RS20790 13b877fa28c8607219f4201de2598558 407 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 352 361 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMALA_RS20790 13b877fa28c8607219f4201de2598558 407 SUPERFAMILY SSF48264 11 406 3.93E-92 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS20790 13b877fa28c8607219f4201de2598558 407 PRINTS PR00359 B-class P450 signature 350 359 3.2E-57 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS20790 13b877fa28c8607219f4201de2598558 407 PRINTS PR00359 B-class P450 signature 329 344 3.2E-57 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS20790 13b877fa28c8607219f4201de2598558 407 PRINTS PR00359 B-class P450 signature 359 370 3.2E-57 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS20790 13b877fa28c8607219f4201de2598558 407 PRINTS PR00359 B-class P450 signature 142 158 3.2E-57 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS20790 13b877fa28c8607219f4201de2598558 407 PRINTS PR00359 B-class P450 signature 202 224 3.2E-57 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS20790 13b877fa28c8607219f4201de2598558 407 PRINTS PR00359 B-class P450 signature 96 107 3.2E-57 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS20790 13b877fa28c8607219f4201de2598558 407 PRINTS PR00359 B-class P450 signature 284 295 3.2E-57 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS20790 13b877fa28c8607219f4201de2598558 407 PRINTS PR00359 B-class P450 signature 301 328 3.2E-57 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS20790 13b877fa28c8607219f4201de2598558 407 PRINTS PR00359 B-class P450 signature 159 174 3.2E-57 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS20790 13b877fa28c8607219f4201de2598558 407 Pfam PF00067 Cytochrome P450 188 378 4.2E-19 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS20790 13b877fa28c8607219f4201de2598558 407 Gene3D G3DSA:1.10.630.10 5 406 1.2E-70 T 29-03-2018 SMALA_RS07785 5c83faac0bfe07af0fde61bd2a73f184 289 SUPERFAMILY SSF51197 6 259 2.66E-34 T 29-03-2018 SMALA_RS07785 5c83faac0bfe07af0fde61bd2a73f184 289 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 18 216 8.5E-11 T 29-03-2018 IPR008775 Phytanoyl-CoA dioxygenase SMALA_RS07785 5c83faac0bfe07af0fde61bd2a73f184 289 Gene3D G3DSA:2.60.120.620 1 228 9.3E-30 T 29-03-2018 SMALA_RS34190 cc04499f41e4a58b62ab631c23efb84e 531 Pfam PF00474 Sodium:solute symporter family 44 453 9.5E-88 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 SMALA_RS35750 6818e7932cfaf230dfae19e69cfeffee 492 Pfam PF00106 short chain dehydrogenase 156 244 3.0E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS35750 6818e7932cfaf230dfae19e69cfeffee 492 Gene3D G3DSA:3.40.50.720 142 480 1.4E-50 T 29-03-2018 SMALA_RS35750 6818e7932cfaf230dfae19e69cfeffee 492 SUPERFAMILY SSF51735 150 247 2.17E-26 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS35750 6818e7932cfaf230dfae19e69cfeffee 492 SUPERFAMILY SSF51735 335 461 2.17E-26 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS04585 98f9e856226b3612825f80aecc9be3e2 192 SMART SM00867 7 183 7.2E-17 T 29-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like SMALA_RS04585 98f9e856226b3612825f80aecc9be3e2 192 Pfam PF04264 YceI-like domain 33 182 7.7E-19 T 29-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like SMALA_RS04585 98f9e856226b3612825f80aecc9be3e2 192 SUPERFAMILY SSF101874 15 183 4.71E-24 T 29-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like SMALA_RS04585 98f9e856226b3612825f80aecc9be3e2 192 Gene3D G3DSA:2.40.128.110 6 187 3.9E-30 T 29-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like SMALA_RS17765 ac036adf82ebb1de1244ddef9eef9a8d 260 Gene3D G3DSA:3.40.1410.10 81 255 1.1E-32 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMALA_RS17765 ac036adf82ebb1de1244ddef9eef9a8d 260 SMART SM00345 20 79 4.5E-13 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS17765 ac036adf82ebb1de1244ddef9eef9a8d 260 SUPERFAMILY SSF64288 105 257 7.49E-30 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMALA_RS17765 ac036adf82ebb1de1244ddef9eef9a8d 260 Pfam PF07702 UTRA domain 117 249 4.9E-21 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMALA_RS17765 ac036adf82ebb1de1244ddef9eef9a8d 260 SUPERFAMILY SSF46785 10 83 3.78E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS17765 ac036adf82ebb1de1244ddef9eef9a8d 260 SMART SM00866 114 252 5.0E-17 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMALA_RS17765 ac036adf82ebb1de1244ddef9eef9a8d 260 Pfam PF00392 Bacterial regulatory proteins, gntR family 17 79 2.0E-14 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMALA_RS17765 ac036adf82ebb1de1244ddef9eef9a8d 260 Gene3D G3DSA:1.10.10.10 3 80 4.6E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS09730 0d2d47c22495f1d22aab7576ae616c23 154 Gene3D G3DSA:2.160.20.10 48 151 5.4E-21 T 29-03-2018 IPR012334 Pectin lyase fold SMALA_RS09730 0d2d47c22495f1d22aab7576ae616c23 154 SUPERFAMILY SSF51126 48 146 3.59E-24 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor SMALA_RS31105 3386c5cd3aff16111c7a59b02179f536 392 SUPERFAMILY SSF54909 29 116 1.14E-18 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel SMALA_RS31105 3386c5cd3aff16111c7a59b02179f536 392 Gene3D G3DSA:3.30.70.1090 270 354 3.4E-13 T 29-03-2018 SMALA_RS31105 3386c5cd3aff16111c7a59b02179f536 392 Gene3D G3DSA:3.30.70.1090 149 249 6.8E-26 T 29-03-2018 SMALA_RS31105 3386c5cd3aff16111c7a59b02179f536 392 Pfam PF04486 SchA/CurD like domain 148 258 1.9E-46 T 29-03-2018 IPR007575 SchA/CurD-like domain SMALA_RS31105 3386c5cd3aff16111c7a59b02179f536 392 Gene3D G3DSA:3.30.70.100 25 125 1.7E-16 T 29-03-2018 SMALA_RS31105 3386c5cd3aff16111c7a59b02179f536 392 Pfam PF03992 Antibiotic biosynthesis monooxygenase 29 101 1.8E-15 T 29-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain SMALA_RS39345 458eb2a2f7ca32f415b31fcc343cdbf6 121 Pfam PF04237 YjbR 11 105 3.9E-28 T 29-03-2018 IPR007351 Uncharacterised protein YjbR SMALA_RS39345 458eb2a2f7ca32f415b31fcc343cdbf6 121 SUPERFAMILY SSF142906 2 118 1.02E-38 T 29-03-2018 SMALA_RS40815 cb29a28fd9fd598f61d5c72e68b70a6e 208 Gene3D G3DSA:1.20.910.10 7 207 2.3E-25 T 29-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 SMALA_RS40815 cb29a28fd9fd598f61d5c72e68b70a6e 208 SUPERFAMILY SSF48613 3 205 8.71E-31 T 29-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 SMALA_RS14145 60055830bc46c42658f11d219db8aa29 131 Pfam PF01022 Bacterial regulatory protein, arsR family 9 58 3.3E-14 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS14145 60055830bc46c42658f11d219db8aa29 131 SMART SM00418 2 84 8.2E-21 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS14145 60055830bc46c42658f11d219db8aa29 131 Gene3D G3DSA:1.10.10.10 1 110 7.9E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS14145 60055830bc46c42658f11d219db8aa29 131 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 4 19 3.8E-11 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS14145 60055830bc46c42658f11d219db8aa29 131 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 40 55 3.8E-11 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS14145 60055830bc46c42658f11d219db8aa29 131 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 55 70 3.8E-11 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMALA_RS14145 60055830bc46c42658f11d219db8aa29 131 SUPERFAMILY SSF46785 3 100 3.91E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS03055 8f04dae53e49cce6a1b690904442cf5a 300 SUPERFAMILY SSF89392 55 280 1.45E-26 T 29-03-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX SMALA_RS03055 8f04dae53e49cce6a1b690904442cf5a 300 Gene3D G3DSA:3.40.190.10 11 281 2.9E-4 T 29-03-2018 SMALA_RS22865 c9597eddaf9127d53ebc4af17baf3b71 286 Gene3D G3DSA:3.20.20.370 7 286 2.8E-44 T 29-03-2018 SMALA_RS22865 c9597eddaf9127d53ebc4af17baf3b71 286 SUPERFAMILY SSF88713 5 285 2.05E-60 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 SMALA_RS22865 c9597eddaf9127d53ebc4af17baf3b71 286 Pfam PF01522 Polysaccharide deacetylase 63 174 2.1E-10 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 SMALA_RS19005 0ace330342c0fdf91176052e36ae0617 99 PIRSF PIRSF006909 1 99 4.0E-58 T 29-03-2018 IPR014447 Uncharacterised conserved protein UCP006909 SMALA_RS21970 64605b30f8fe11994d994b05b0816489 364 Pfam PF01578 Cytochrome C assembly protein 141 356 1.7E-47 T 29-03-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 SMALA_RS21970 64605b30f8fe11994d994b05b0816489 364 TIGRFAM TIGR03144 cytochr_II_ccsB: cytochrome c-type biogenesis protein CcsB 118 362 7.0E-78 T 29-03-2018 IPR017562 Cytochrome c-type biogenesis protein CcsA GO:0017004 SMALA_RS18245 9e2fa18a0ad6fe9b5ac3961605a01e57 174 Pfam PF13490 Putative zinc-finger 33 61 6.8E-8 T 29-03-2018 IPR027383 Putative zinc-finger SMALA_RS19970 32492962ae59d7d6392de38e6e04fba1 387 Gene3D G3DSA:3.40.50.970 30 365 1.3E-82 T 29-03-2018 SMALA_RS19970 32492962ae59d7d6392de38e6e04fba1 387 SUPERFAMILY SSF52518 43 367 1.16E-92 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold SMALA_RS19970 32492962ae59d7d6392de38e6e04fba1 387 Pfam PF00676 Dehydrogenase E1 component 64 341 2.2E-71 T 29-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 SMALA_RS19970 32492962ae59d7d6392de38e6e04fba1 387 TIGRFAM TIGR03181 PDH_E1_alph_x: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 39 364 2.1E-125 T 29-03-2018 IPR017596 Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 SMALA_RS26980 f3b6e44fb5e535d29466857c2ec85fb9 912 Gene3D G3DSA:3.40.50.300 152 315 8.3E-9 T 29-03-2018 SMALA_RS26980 f3b6e44fb5e535d29466857c2ec85fb9 912 PRINTS PR01217 Proline rich extensin signature 863 888 3.6E-9 T 29-03-2018 SMALA_RS26980 f3b6e44fb5e535d29466857c2ec85fb9 912 PRINTS PR01217 Proline rich extensin signature 684 696 3.6E-9 T 29-03-2018 SMALA_RS26980 f3b6e44fb5e535d29466857c2ec85fb9 912 PRINTS PR01217 Proline rich extensin signature 808 824 3.6E-9 T 29-03-2018 SMALA_RS26980 f3b6e44fb5e535d29466857c2ec85fb9 912 PRINTS PR01217 Proline rich extensin signature 834 851 3.6E-9 T 29-03-2018 SMALA_RS26980 f3b6e44fb5e535d29466857c2ec85fb9 912 SUPERFAMILY SSF52540 163 361 2.97E-9 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS18730 0c92503aa40339e6be8a7775462467e6 128 Gene3D G3DSA:3.10.180.10 3 128 7.8E-18 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS18730 0c92503aa40339e6be8a7775462467e6 128 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 119 1.7E-4 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMALA_RS18730 0c92503aa40339e6be8a7775462467e6 128 SUPERFAMILY SSF54593 5 124 1.06E-18 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS08975 88eab64bf4b2aed8d34b29e32376c4a4 191 Gene3D G3DSA:3.90.1570.10 7 186 1.3E-26 T 29-03-2018 SMALA_RS08975 88eab64bf4b2aed8d34b29e32376c4a4 191 SUPERFAMILY SSF52980 23 164 5.36E-18 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 SMALA_RS08975 88eab64bf4b2aed8d34b29e32376c4a4 191 Pfam PF05685 Putative restriction endonuclease 24 149 1.4E-19 T 29-03-2018 IPR008538 Domain of unknown function DUF820 SMALA_RS26165 d5555fba592673fbabba91fc895840bc 458 SUPERFAMILY SSF55205 22 446 2.62E-99 T 29-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 SMALA_RS26165 d5555fba592673fbabba91fc895840bc 458 Gene3D G3DSA:3.65.10.10 252 448 6.4E-47 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 SMALA_RS26165 d5555fba592673fbabba91fc895840bc 458 PIRSF PIRSF000505 13 453 4.1E-110 T 29-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 SMALA_RS26165 d5555fba592673fbabba91fc895840bc 458 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 22 450 28.405 T 29-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 SMALA_RS26165 d5555fba592673fbabba91fc895840bc 458 ProSitePatterns PS00885 EPSP synthase signature 2. 363 381 - T 29-03-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 SMALA_RS26165 d5555fba592673fbabba91fc895840bc 458 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 21 441 5.3E-104 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 SMALA_RS26165 d5555fba592673fbabba91fc895840bc 458 Gene3D G3DSA:3.65.10.10 33 251 2.8E-54 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 SMALA_RS26165 d5555fba592673fbabba91fc895840bc 458 ProSitePatterns PS00104 EPSP synthase signature 1. 110 124 - T 29-03-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 SMALA_RS26165 d5555fba592673fbabba91fc895840bc 458 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 27 446 2.5E-110 T 29-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 SMALA_RS19200 3d63d8d288de1e58c2a5d2c14b16f205 166 Gene3D G3DSA:3.10.129.10 10 142 1.5E-27 T 29-03-2018 SMALA_RS19200 3d63d8d288de1e58c2a5d2c14b16f205 166 SUPERFAMILY SSF54637 13 128 7.46E-20 T 29-03-2018 IPR029069 HotDog domain SMALA_RS19200 3d63d8d288de1e58c2a5d2c14b16f205 166 Pfam PF01575 MaoC like domain 21 122 7.6E-9 T 29-03-2018 IPR002539 MaoC-like domain SMALA_RS34015 139b3d4fdab3b9563ac87b81aa976b37 313 Gene3D G3DSA:3.40.50.20 4 103 1.0E-9 T 29-03-2018 SMALA_RS34015 139b3d4fdab3b9563ac87b81aa976b37 313 Gene3D G3DSA:3.90.25.10 154 312 1.8E-13 T 29-03-2018 SMALA_RS34015 139b3d4fdab3b9563ac87b81aa976b37 313 SUPERFAMILY SSF51735 10 309 3.84E-36 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS34015 139b3d4fdab3b9563ac87b81aa976b37 313 Pfam PF01370 NAD dependent epimerase/dehydratase family 10 206 3.1E-12 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 SMALA_RS04935 4db6824441c5a6001767fb35acb91f33 337 Gene3D G3DSA:1.10.3470.10 1 337 8.0E-69 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SMALA_RS04935 4db6824441c5a6001767fb35acb91f33 337 SUPERFAMILY SSF81345 4 332 6.93E-76 T 29-03-2018 IPR029022 ABC transporter, BtuC-like SMALA_RS04935 4db6824441c5a6001767fb35acb91f33 337 Pfam PF01032 FecCD transport family 16 332 1.1E-88 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 SMALA_RS42255 333b9407ebdd0187f5e26144a86a9930 297 Pfam PF08241 Methyltransferase domain 81 158 6.1E-10 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 SMALA_RS42255 333b9407ebdd0187f5e26144a86a9930 297 SUPERFAMILY SSF53335 55 211 4.78E-18 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS42255 333b9407ebdd0187f5e26144a86a9930 297 Gene3D G3DSA:3.40.50.150 9 249 3.0E-18 T 29-03-2018 SMALA_RS04095 9580195aefb06ac3ccd0d6e6e4adc326 227 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 8 218 4.2E-34 T 29-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 SMALA_RS04095 9580195aefb06ac3ccd0d6e6e4adc326 227 SUPERFAMILY SSF51695 3 221 3.4E-61 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 SMALA_RS04095 9580195aefb06ac3ccd0d6e6e4adc326 227 Gene3D G3DSA:3.20.20.190 2 226 9.4E-58 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 SMALA_RS37805 c3bf602fdc4a774a06319cd4f6054509 1564 Gene3D G3DSA:1.20.5.1230 477 911 1.7E-12 T 29-03-2018 SMALA_RS01520 52022dbc9ab4b16dfa1164debe5ebc11 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 6.1E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS01520 52022dbc9ab4b16dfa1164debe5ebc11 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 6.1E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS01520 52022dbc9ab4b16dfa1164debe5ebc11 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 6.1E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS01520 52022dbc9ab4b16dfa1164debe5ebc11 264 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 258 1.6E-44 T 29-03-2018 SMALA_RS01520 52022dbc9ab4b16dfa1164debe5ebc11 264 Gene3D G3DSA:3.40.50.720 1 262 1.4E-60 T 29-03-2018 SMALA_RS01520 52022dbc9ab4b16dfa1164debe5ebc11 264 SUPERFAMILY SSF51735 3 259 3.4E-67 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS01520 52022dbc9ab4b16dfa1164debe5ebc11 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 4.4E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS01520 52022dbc9ab4b16dfa1164debe5ebc11 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 4.4E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS01520 52022dbc9ab4b16dfa1164debe5ebc11 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 4.4E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS01520 52022dbc9ab4b16dfa1164debe5ebc11 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 4.4E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS01520 52022dbc9ab4b16dfa1164debe5ebc11 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 4.4E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS01520 52022dbc9ab4b16dfa1164debe5ebc11 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 4.4E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS01520 52022dbc9ab4b16dfa1164debe5ebc11 264 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMALA_RS33365 0dd0733847eb0b60109e4aa21caa0b50 118 Pfam PF05610 Protein of unknown function (DUF779) 13 112 1.1E-47 T 29-03-2018 IPR008497 Protein of unknown function DUF779 SMALA_RS33365 0dd0733847eb0b60109e4aa21caa0b50 118 PIRSF PIRSF009151 1 118 6.1E-59 T 29-03-2018 IPR008497 Protein of unknown function DUF779 SMALA_RS35080 1c4bcacfb40b72f7054874bdaa09bc8c 391 Pfam PF13556 PucR C-terminal helix-turn-helix domain 293 347 8.0E-17 T 29-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain SMALA_RS35080 1c4bcacfb40b72f7054874bdaa09bc8c 391 Gene3D G3DSA:1.10.10.10 272 372 1.3E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS17525 4c16b9d7c6fab7a50f1a7dce9199052a 492 Gene3D G3DSA:3.40.50.2000 5 286 1.8E-66 T 29-03-2018 SMALA_RS17525 4c16b9d7c6fab7a50f1a7dce9199052a 492 SUPERFAMILY SSF53756 9 492 4.33E-108 T 29-03-2018 SMALA_RS17525 4c16b9d7c6fab7a50f1a7dce9199052a 492 Gene3D G3DSA:3.40.50.2000 287 476 8.0E-36 T 29-03-2018 SMALA_RS17525 4c16b9d7c6fab7a50f1a7dce9199052a 492 Pfam PF00982 Glycosyltransferase family 20 13 489 3.8E-105 T 29-03-2018 IPR001830 Glycosyl transferase, family 20 GO:0003824|GO:0005992 SMALA_RS01015 5e682da530301d934ce56e15172ae979 74 Pfam PF09489 Probable cobalt transporter subunit (CbtB) 26 74 9.6E-13 T 29-03-2018 IPR012667 Cobalt transporter subunit CbtB, putative SMALA_RS16935 b5f083df185971f7b80ff8222fbb34cc 604 Pfam PF01551 Peptidase family M23 499 592 1.4E-27 T 29-03-2018 IPR016047 Peptidase M23 SMALA_RS16935 b5f083df185971f7b80ff8222fbb34cc 604 Gene3D G3DSA:2.70.70.10 431 599 1.4E-42 T 29-03-2018 SMALA_RS16935 b5f083df185971f7b80ff8222fbb34cc 604 SUPERFAMILY SSF51261 475 596 1.41E-40 T 29-03-2018 IPR011055 Duplicated hybrid motif SMALA_RS04190 75adf464902524be00d72af915ac344c 139 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 7 91 1.2E-13 T 29-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 SMALA_RS04190 75adf464902524be00d72af915ac344c 139 Gene3D G3DSA:2.30.110.10 1 128 7.1E-23 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS04190 75adf464902524be00d72af915ac344c 139 SUPERFAMILY SSF50475 6 130 6.22E-27 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS04190 75adf464902524be00d72af915ac344c 139 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 11 128 2.5E-29 T 29-03-2018 IPR019920 F420-binding domain, putative SMALA_RS15015 ec01b87b9ed0dd3442689d7cf507918d 77 SUPERFAMILY SSF55604 5 76 1.7E-22 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 SMALA_RS15015 ec01b87b9ed0dd3442689d7cf507918d 77 Pfam PF00367 phosphotransferase system, EIIB 7 39 7.3E-14 T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 SMALA_RS15015 ec01b87b9ed0dd3442689d7cf507918d 77 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 3 63 7.5E-18 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 SMALA_RS15015 ec01b87b9ed0dd3442689d7cf507918d 77 Gene3D G3DSA:3.30.1360.60 2 77 1.6E-27 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 SMALA_RS35515 453a03342ad4c760d096f8a8c511afa7 89 SUPERFAMILY SSF143212 3 83 1.31E-21 T 29-03-2018 SMALA_RS35515 453a03342ad4c760d096f8a8c511afa7 89 Pfam PF08962 Domain of unknown function (DUF1876) 7 86 1.2E-28 T 29-03-2018 IPR015057 Protein of unknown function DUF1876 SMALA_RS35515 453a03342ad4c760d096f8a8c511afa7 89 ProDom PD280340 RV1738/MT1780 MB2665C MB1767 SCO3163 RV2632C/MT2708 3 78 1.0E-12 T 29-03-2018 IPR015057 Protein of unknown function DUF1876 SMALA_RS18010 2c589d0ffefa0406b0948e9253098991 311 Gene3D G3DSA:3.40.50.720 14 180 1.9E-22 T 29-03-2018 SMALA_RS18010 2c589d0ffefa0406b0948e9253098991 311 SUPERFAMILY SSF48179 182 281 6.12E-24 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMALA_RS18010 2c589d0ffefa0406b0948e9253098991 311 Gene3D G3DSA:1.10.1040.20 181 278 1.7E-36 T 29-03-2018 IPR018931 Domain of unknown function DUF2520 SMALA_RS18010 2c589d0ffefa0406b0948e9253098991 311 Pfam PF10728 Domain of unknown function (DUF2520) 149 274 1.5E-37 T 29-03-2018 IPR018931 Domain of unknown function DUF2520 SMALA_RS18010 2c589d0ffefa0406b0948e9253098991 311 Pfam PF10727 Rossmann-like domain 8 132 2.5E-42 T 29-03-2018 IPR019665 Putative oxidoreductase/dehydrogenase, Rossmann-like domain SMALA_RS18010 2c589d0ffefa0406b0948e9253098991 311 SUPERFAMILY SSF51735 18 180 6.98E-26 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS05925 8a15618c30b44071ca5859b152f1ae65 484 Gene3D G3DSA:1.10.630.10 10 455 5.6E-114 T 29-03-2018 SMALA_RS05925 8a15618c30b44071ca5859b152f1ae65 484 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 391 400 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMALA_RS05925 8a15618c30b44071ca5859b152f1ae65 484 PRINTS PR00463 E-class P450 group I signature 39 58 3.8E-23 T 29-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS05925 8a15618c30b44071ca5859b152f1ae65 484 PRINTS PR00463 E-class P450 group I signature 398 421 3.8E-23 T 29-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS05925 8a15618c30b44071ca5859b152f1ae65 484 PRINTS PR00463 E-class P450 group I signature 388 398 3.8E-23 T 29-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS05925 8a15618c30b44071ca5859b152f1ae65 484 PRINTS PR00463 E-class P450 group I signature 274 300 3.8E-23 T 29-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS05925 8a15618c30b44071ca5859b152f1ae65 484 PRINTS PR00463 E-class P450 group I signature 254 271 3.8E-23 T 29-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS05925 8a15618c30b44071ca5859b152f1ae65 484 PRINTS PR00463 E-class P450 group I signature 356 380 3.8E-23 T 29-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS05925 8a15618c30b44071ca5859b152f1ae65 484 SUPERFAMILY SSF48264 15 449 1.83E-105 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS05925 8a15618c30b44071ca5859b152f1ae65 484 Pfam PF00067 Cytochrome P450 13 436 1.1E-80 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS05925 8a15618c30b44071ca5859b152f1ae65 484 PRINTS PR00385 P450 superfamily signature 398 409 5.1E-14 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS05925 8a15618c30b44071ca5859b152f1ae65 484 PRINTS PR00385 P450 superfamily signature 317 328 5.1E-14 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS05925 8a15618c30b44071ca5859b152f1ae65 484 PRINTS PR00385 P450 superfamily signature 265 282 5.1E-14 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS05925 8a15618c30b44071ca5859b152f1ae65 484 PRINTS PR00385 P450 superfamily signature 389 398 5.1E-14 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS03110 86466042d88114d27d0dd96314cefb2f 191 SUPERFAMILY SSF48498 82 187 4.04E-7 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS03110 86466042d88114d27d0dd96314cefb2f 191 SUPERFAMILY SSF46689 2 60 1.59E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS03110 86466042d88114d27d0dd96314cefb2f 191 Pfam PF00440 Bacterial regulatory proteins, tetR family 2 48 1.9E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS03110 86466042d88114d27d0dd96314cefb2f 191 Gene3D G3DSA:1.10.357.10 1 191 4.3E-23 T 29-03-2018 SMALA_RS23760 31401693a8ff222572a460f04641d0a9 160 Pfam PF01967 MoaC family 19 152 4.7E-53 T 29-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 SMALA_RS23760 31401693a8ff222572a460f04641d0a9 160 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 8 154 3.5E-63 T 29-03-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 Reactome: R-HSA-947581 SMALA_RS23760 31401693a8ff222572a460f04641d0a9 160 Gene3D G3DSA:3.30.70.640 6 160 5.2E-67 T 29-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 SMALA_RS23760 31401693a8ff222572a460f04641d0a9 160 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase accessory protein [moaC]. 6 160 36.407 T 29-03-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 Reactome: R-HSA-947581 SMALA_RS23760 31401693a8ff222572a460f04641d0a9 160 SUPERFAMILY SSF55040 15 157 1.57E-57 T 29-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 SMALA_RS21680 4f89fbc717dcbff7c9b7127cb2f85b2e 313 ProDom PD040376 SCO3349 RV0495C/MT0515 ML2435 MB0506C CGL0407 58 299 3.0E-122 T 29-03-2018 SMALA_RS36860 950d7b64838f0aa084f1f39651e81ad9 394 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 151 166 2.3E-11 T 29-03-2018 SMALA_RS36860 950d7b64838f0aa084f1f39651e81ad9 394 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 289 304 2.3E-11 T 29-03-2018 SMALA_RS36860 950d7b64838f0aa084f1f39651e81ad9 394 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 2.3E-11 T 29-03-2018 SMALA_RS36860 950d7b64838f0aa084f1f39651e81ad9 394 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 304 320 2.3E-11 T 29-03-2018 SMALA_RS36860 950d7b64838f0aa084f1f39651e81ad9 394 Pfam PF01494 FAD binding domain 6 346 3.4E-16 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 SMALA_RS36860 950d7b64838f0aa084f1f39651e81ad9 394 Gene3D G3DSA:3.50.50.60 1 327 7.9E-35 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS36860 950d7b64838f0aa084f1f39651e81ad9 394 SUPERFAMILY SSF51905 276 360 1.2E-47 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS36860 950d7b64838f0aa084f1f39651e81ad9 394 SUPERFAMILY SSF51905 6 172 1.2E-47 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS01290 7e03193f89c1d84f421ce5dc1500e8ee 133 Pfam PF07179 SseB protein N-terminal domain 14 123 9.0E-12 T 29-03-2018 IPR009839 SseB protein N-terminal domain SMALA_RS14820 699458c0ae394afa15fde1d12209ebc4 197 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 29 195 6.0E-41 T 29-03-2018 IPR004302 Cellulose/chitin-binding protein, N-terminal SMALA_RS14820 699458c0ae394afa15fde1d12209ebc4 197 Gene3D G3DSA:2.70.50.50 29 197 3.6E-56 T 29-03-2018 SMALA_RS14820 699458c0ae394afa15fde1d12209ebc4 197 SUPERFAMILY SSF81296 29 197 4.76E-60 T 29-03-2018 IPR014756 Immunoglobulin E-set SMALA_RS36075 5990202f675a3e55ee8a0f499159f3bd 78 Gene3D G3DSA:3.30.1660.10 3 67 8.1E-32 T 29-03-2018 IPR025543 Dodecin-like SMALA_RS36075 5990202f675a3e55ee8a0f499159f3bd 78 Pfam PF07311 Dodecin 4 67 1.5E-30 T 29-03-2018 IPR009923 Dodecin SMALA_RS36075 5990202f675a3e55ee8a0f499159f3bd 78 SUPERFAMILY SSF89807 3 67 5.89E-26 T 29-03-2018 IPR009923 Dodecin SMALA_RS14945 e0696861d5b3dd9587616429fbf85fce 450 Pfam PF04286 Protein of unknown function (DUF445) 85 446 1.3E-97 T 29-03-2018 IPR007383 Protein of unknown function DUF445 SMALA_RS42525 ca7a2f8ea599c23059474c80c5595b3f 451 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 9 430 1.5E-132 T 29-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 SMALA_RS42525 ca7a2f8ea599c23059474c80c5595b3f 451 SUPERFAMILY SSF51679 4 437 2.09E-115 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS42525 ca7a2f8ea599c23059474c80c5595b3f 451 PIRSF PIRSF000337 2 445 1.6E-136 T 29-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 SMALA_RS42525 ca7a2f8ea599c23059474c80c5595b3f 451 Gene3D G3DSA:3.20.20.30 1 448 7.7E-101 T 29-03-2018 SMALA_RS42525 ca7a2f8ea599c23059474c80c5595b3f 451 Pfam PF00296 Luciferase-like monooxygenase 20 386 1.8E-63 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS28380 89258c51ed0d77036e38e3e93e28c39b 587 Gene3D G3DSA:3.40.50.2300 45 157 1.0E-4 T 29-03-2018 SMALA_RS28380 89258c51ed0d77036e38e3e93e28c39b 587 Pfam PF13556 PucR C-terminal helix-turn-helix domain 522 580 7.3E-23 T 29-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain SMALA_RS28380 89258c51ed0d77036e38e3e93e28c39b 587 Pfam PF07905 Purine catabolism regulatory protein-like family 8 126 1.1E-32 T 29-03-2018 IPR012914 Purine catabolism PurC-like domain SMALA_RS28380 89258c51ed0d77036e38e3e93e28c39b 587 Gene3D G3DSA:1.10.10.60 507 558 7.5E-6 T 29-03-2018 SMALA_RS43025 05984c05361bc3c71e16cc713080c602 222 SMART SM00530 20 77 0.66 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS43025 05984c05361bc3c71e16cc713080c602 222 SMART SM00530 115 180 4.9 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS43025 05984c05361bc3c71e16cc713080c602 222 Gene3D G3DSA:1.10.260.40 104 178 0.0012 T 29-03-2018 SMALA_RS43025 05984c05361bc3c71e16cc713080c602 222 Gene3D G3DSA:1.10.260.40 7 78 3.7E-9 T 29-03-2018 SMALA_RS43025 05984c05361bc3c71e16cc713080c602 222 Pfam PF13560 Helix-turn-helix domain 16 76 4.2E-9 T 29-03-2018 SMALA_RS43025 05984c05361bc3c71e16cc713080c602 222 SUPERFAMILY SSF47413 15 74 1.6E-6 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS15455 53c2c638fe57a0e227dad920a3b0720d 535 TIGRFAM TIGR00666 PBP4: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase 75 477 3.1E-103 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 SMALA_RS15455 53c2c638fe57a0e227dad920a3b0720d 535 SUPERFAMILY SSF56601 47 490 5.01E-91 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMALA_RS15455 53c2c638fe57a0e227dad920a3b0720d 535 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 387 401 1.3E-28 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 SMALA_RS15455 53c2c638fe57a0e227dad920a3b0720d 535 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 372 386 1.3E-28 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 SMALA_RS15455 53c2c638fe57a0e227dad920a3b0720d 535 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 87 106 1.3E-28 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 SMALA_RS15455 53c2c638fe57a0e227dad920a3b0720d 535 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 454 467 1.3E-28 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 SMALA_RS15455 53c2c638fe57a0e227dad920a3b0720d 535 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 315 337 1.3E-28 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 SMALA_RS15455 53c2c638fe57a0e227dad920a3b0720d 535 Gene3D G3DSA:3.40.710.10 44 505 2.9E-39 T 29-03-2018 SMALA_RS15455 53c2c638fe57a0e227dad920a3b0720d 535 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 50 496 1.3E-127 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 SMALA_RS37115 48b1c17df01f91e16e709145b2214fa7 231 Pfam PF14065 Protein of unknown function (DUF4255) 4 178 5.8E-47 T 29-03-2018 IPR025351 Protein of unknown function DUF4255 SMALA_RS27335 d6855fc0bd81382f08b95f3574057d96 264 SUPERFAMILY SSF51126 47 225 1.88E-55 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor SMALA_RS27335 d6855fc0bd81382f08b95f3574057d96 264 Gene3D G3DSA:2.160.20.10 52 263 4.1E-85 T 29-03-2018 IPR012334 Pectin lyase fold SMALA_RS27335 d6855fc0bd81382f08b95f3574057d96 264 Pfam PF03211 Pectate lyase 37 237 9.1E-80 T 29-03-2018 IPR004898 Pectate lyase PlyH/PlyE-like GO:0005576|GO:0030570 KEGG: 00040+4.2.2.2 SMALA_RS01065 5391ddecdcd49c57fd47ac051e4bb872 160 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 6 119 3.3E-48 T 29-03-2018 IPR028973 PhnB-like SMALA_RS01065 5391ddecdcd49c57fd47ac051e4bb872 160 SUPERFAMILY SSF54593 6 158 9.0E-51 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS01065 5391ddecdcd49c57fd47ac051e4bb872 160 PIRSF PIRSF021700 1 159 5.9E-63 T 29-03-2018 IPR009725 Predicted 3-demethylubiquinone-9 3-methyltransferase SMALA_RS01065 5391ddecdcd49c57fd47ac051e4bb872 160 Gene3D G3DSA:3.10.180.10 1 129 1.2E-21 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS27405 36847aa44b9e898c9330d5188b35bc49 320 Pfam PF06675 Protein of unknown function (DUF1177) 47 315 1.3E-129 T 29-03-2018 IPR009561 Protein of unknown function DUF1177 SMALA_RS24080 0d91e7c423f9d0d765668af1b2dc2bba 173 Pfam PF14431 YwqJ-like deaminase 43 166 2.4E-26 T 29-03-2018 IPR025968 YwqJ-like deaminase SMALA_RS32315 0606b31f0cc7c36ecffa66d2cbadfcc5 277 Gene3D G3DSA:3.40.1280.10 105 267 5.9E-45 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal SMALA_RS32315 0606b31f0cc7c36ecffa66d2cbadfcc5 277 Pfam PF00588 SpoU rRNA Methylase family 115 259 2.2E-36 T 29-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 SMALA_RS32315 0606b31f0cc7c36ecffa66d2cbadfcc5 277 Gene3D G3DSA:3.30.1330.30 2 100 1.5E-28 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like SMALA_RS32315 0606b31f0cc7c36ecffa66d2cbadfcc5 277 SUPERFAMILY SSF75217 92 267 4.25E-41 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases SMALA_RS32315 0606b31f0cc7c36ecffa66d2cbadfcc5 277 SUPERFAMILY SSF55315 5 100 8.0E-21 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like SMALA_RS32315 0606b31f0cc7c36ecffa66d2cbadfcc5 277 SMART SM00967 33 104 9.3E-15 T 29-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 SMALA_RS32315 0606b31f0cc7c36ecffa66d2cbadfcc5 277 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 33 101 3.7E-12 T 29-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 SMALA_RS29195 b00bef9566e3c551f403b9d70ca82d50 100 Pfam PF13834 Domain of unknown function (DUF4193) 1 99 1.1E-44 T 29-03-2018 IPR025242 Protein of unknown function DUF4193 SMALA_RS10345 30af5c44733d50d3876d62f55aa29643 66 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 3 66 7.1E-23 T 29-03-2018 IPR010035 ThiS, thiamine-biosynthesis SMALA_RS10345 30af5c44733d50d3876d62f55aa29643 66 SUPERFAMILY SSF54285 1 66 4.65E-18 T 29-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp SMALA_RS10345 30af5c44733d50d3876d62f55aa29643 66 Pfam PF02597 ThiS family 3 66 9.4E-17 T 29-03-2018 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 SMALA_RS10345 30af5c44733d50d3876d62f55aa29643 66 Gene3D G3DSA:3.10.20.30 1 66 9.1E-27 T 29-03-2018 IPR012675 Beta-grasp domain SMALA_RS32060 6a9cf905652cd035c516659c6a67d31b 263 Pfam PF01066 CDP-alcohol phosphatidyltransferase 53 118 2.5E-8 T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 SMALA_RS16400 de2a5b337c58341281547273908fc50a 227 Pfam PF10756 Bacterial PH domain 85 134 7.0E-9 T 29-03-2018 IPR019692 Protein of unknown function DUF2581 SMALA_RS10175 446a95ced9ee728977bda08239795782 1045 Gene3D G3DSA:1.10.730.10 639 823 4.1E-41 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMALA_RS10175 446a95ced9ee728977bda08239795782 1045 Hamap MF_02003 Isoleucine--tRNA ligase [ileS]. 6 1043 13.703 T 29-03-2018 IPR023586 Isoleucine-tRNA ligase, type 2 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 SMALA_RS10175 446a95ced9ee728977bda08239795782 1045 SUPERFAMILY SSF52374 392 646 1.64E-120 T 29-03-2018 SMALA_RS10175 446a95ced9ee728977bda08239795782 1045 SUPERFAMILY SSF52374 8 201 1.64E-120 T 29-03-2018 SMALA_RS10175 446a95ced9ee728977bda08239795782 1045 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 8 837 3.0E-266 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 SMALA_RS10175 446a95ced9ee728977bda08239795782 1045 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 557 566 1.1E-25 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 SMALA_RS10175 446a95ced9ee728977bda08239795782 1045 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 227 250 1.1E-25 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 SMALA_RS10175 446a95ced9ee728977bda08239795782 1045 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 44 55 1.1E-25 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 SMALA_RS10175 446a95ced9ee728977bda08239795782 1045 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 390 405 1.1E-25 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 SMALA_RS10175 446a95ced9ee728977bda08239795782 1045 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 517 530 1.1E-25 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 SMALA_RS10175 446a95ced9ee728977bda08239795782 1045 SUPERFAMILY SSF50677 204 392 7.53E-45 T 29-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 SMALA_RS10175 446a95ced9ee728977bda08239795782 1045 SUPERFAMILY SSF47323 653 887 2.43E-48 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMALA_RS10175 446a95ced9ee728977bda08239795782 1045 Pfam PF08264 Anticodon-binding domain of tRNA 685 830 8.5E-30 T 29-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 SMALA_RS10175 446a95ced9ee728977bda08239795782 1045 Gene3D G3DSA:3.40.50.620 5 636 5.3E-126 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS10175 446a95ced9ee728977bda08239795782 1045 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 21 626 9.3E-166 T 29-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMALA_RS26290 fc893a7677d3265f66928b3c22527328 86 Pfam PF11755 Protein of unknown function (DUF3311) 24 82 1.6E-23 T 29-03-2018 IPR021741 Protein of unknown function DUF3311 SMALA_RS33275 d13aff4cba1fe1e28ec1555cefd63401 410 Gene3D G3DSA:1.20.1250.20 207 393 5.1E-14 T 29-03-2018 SMALA_RS33275 d13aff4cba1fe1e28ec1555cefd63401 410 Gene3D G3DSA:1.20.1250.20 13 205 9.3E-18 T 29-03-2018 SMALA_RS33275 d13aff4cba1fe1e28ec1555cefd63401 410 Pfam PF07690 Major Facilitator Superfamily 24 349 4.4E-20 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS33275 d13aff4cba1fe1e28ec1555cefd63401 410 SUPERFAMILY SSF103473 14 386 1.1E-37 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS05755 b27cb61317926350446de4951fdf72d8 148 Pfam PF13115 YtkA-like 53 129 6.4E-6 T 29-03-2018 IPR032693 YtkA-like domain SMALA_RS05160 6bad3ed5971502bd33316f8b0f5daf7a 227 Gene3D G3DSA:1.10.357.10 13 224 7.1E-34 T 29-03-2018 SMALA_RS05160 6bad3ed5971502bd33316f8b0f5daf7a 227 SUPERFAMILY SSF46689 13 85 1.41E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS05160 6bad3ed5971502bd33316f8b0f5daf7a 227 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 67 2.1E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS05160 6bad3ed5971502bd33316f8b0f5daf7a 227 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 35 1.0E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS05160 6bad3ed5971502bd33316f8b0f5daf7a 227 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 66 1.0E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS16915 3785042ab705af9bd2c68d017d30d51e 487 Pfam PF04434 SWIM zinc finger 61 88 5.3E-6 T 29-03-2018 IPR007527 Zinc finger, SWIM-type GO:0008270 SMALA_RS43230 a34a9621929b4e0d370e0df44273641e 140 SUPERFAMILY SSF88697 2 123 3.33E-11 T 29-03-2018 IPR015947 PUA-like domain SMALA_RS43230 a34a9621929b4e0d370e0df44273641e 140 Gene3D G3DSA:2.30.130.30 1 110 2.5E-17 T 29-03-2018 SMALA_RS33890 153ddf60a24d90f1ae8582d8e06919d5 287 SUPERFAMILY SSF47413 10 75 9.93E-7 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS33890 153ddf60a24d90f1ae8582d8e06919d5 287 Pfam PF13560 Helix-turn-helix domain 13 72 7.5E-11 T 29-03-2018 SMALA_RS33890 153ddf60a24d90f1ae8582d8e06919d5 287 Gene3D G3DSA:1.10.260.40 4 88 3.1E-9 T 29-03-2018 SMALA_RS00205 935158ee9407386cdf694d3f608156d1 308 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 27 44 1.8E-18 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS00205 935158ee9407386cdf694d3f608156d1 308 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 205 222 1.8E-18 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS00205 935158ee9407386cdf694d3f608156d1 308 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 100 111 1.8E-18 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS00205 935158ee9407386cdf694d3f608156d1 308 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 161 1.8E-18 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS00205 935158ee9407386cdf694d3f608156d1 308 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 184 203 1.8E-18 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS00205 935158ee9407386cdf694d3f608156d1 308 Pfam PF00106 short chain dehydrogenase 28 225 8.1E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS00205 935158ee9407386cdf694d3f608156d1 308 Gene3D G3DSA:3.40.50.720 10 307 2.4E-62 T 29-03-2018 SMALA_RS00205 935158ee9407386cdf694d3f608156d1 308 SUPERFAMILY SSF51735 23 270 5.89E-56 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS15275 01bb04b60134420bc5fad5f57b752ede 270 Gene3D G3DSA:2.160.20.20 14 264 1.5E-6 T 29-03-2018 IPR012332 P22 tailspike C-terminal domain-like SMALA_RS05920 ebb4b177a43a239c23909d8375a148e9 342 Gene3D G3DSA:3.40.47.10 169 322 6.2E-25 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS05920 ebb4b177a43a239c23909d8375a148e9 342 Gene3D G3DSA:3.40.47.10 4 168 1.1E-8 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS05920 ebb4b177a43a239c23909d8375a148e9 342 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 230 321 8.9E-13 T 29-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SMALA_RS05920 ebb4b177a43a239c23909d8375a148e9 342 SUPERFAMILY SSF53901 35 323 4.84E-23 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS34365 b8b9bb24cf0a5c260fd55f70650d08da 290 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 1 276 17.893 T 29-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 SMALA_RS34365 b8b9bb24cf0a5c260fd55f70650d08da 290 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 7 269 3.1E-77 T 29-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 SMALA_RS34365 b8b9bb24cf0a5c260fd55f70650d08da 290 Pfam PF02673 Bacitracin resistance protein BacA 7 270 2.0E-83 T 29-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 SMALA_RS03995 8b0e7fc4557747bd998ee63534b2ceea 304 SUPERFAMILY SSF161098 67 289 3.66E-50 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS03995 8b0e7fc4557747bd998ee63534b2ceea 304 Gene3D G3DSA:1.10.3720.10 24 301 7.4E-49 T 29-03-2018 SMALA_RS03995 8b0e7fc4557747bd998ee63534b2ceea 304 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 98 295 5.4E-21 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS02370 ad80258c679fc624b8de5dba81d5fd45 530 SUPERFAMILY SSF51905 276 377 5.56E-59 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS02370 ad80258c679fc624b8de5dba81d5fd45 530 SUPERFAMILY SSF51905 15 187 5.56E-59 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS02370 ad80258c679fc624b8de5dba81d5fd45 530 Pfam PF01494 FAD binding domain 14 354 3.0E-61 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 SMALA_RS02370 ad80258c679fc624b8de5dba81d5fd45 530 Gene3D G3DSA:3.50.50.60 12 389 1.3E-48 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS02370 ad80258c679fc624b8de5dba81d5fd45 530 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 289 304 9.2E-35 T 29-03-2018 SMALA_RS02370 ad80258c679fc624b8de5dba81d5fd45 530 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 304 320 9.2E-35 T 29-03-2018 SMALA_RS02370 ad80258c679fc624b8de5dba81d5fd45 530 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 340 356 9.2E-35 T 29-03-2018 SMALA_RS02370 ad80258c679fc624b8de5dba81d5fd45 530 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 166 181 9.2E-35 T 29-03-2018 SMALA_RS02370 ad80258c679fc624b8de5dba81d5fd45 530 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 16 38 9.2E-35 T 29-03-2018 SMALA_RS02370 ad80258c679fc624b8de5dba81d5fd45 530 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 322 340 9.2E-35 T 29-03-2018 SMALA_RS11025 e72e2e94eac74b8c74d3bc6415c984a5 310 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 303 7.3E-14 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS11025 e72e2e94eac74b8c74d3bc6415c984a5 310 SUPERFAMILY SSF161098 68 293 1.96E-45 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS11025 e72e2e94eac74b8c74d3bc6415c984a5 310 Gene3D G3DSA:1.10.3720.10 20 305 5.5E-42 T 29-03-2018 SMALA_RS33660 b281ee91682bc578dedc52dcc7ae0701 304 Gene3D G3DSA:2.60.120.620 2 245 6.0E-26 T 29-03-2018 SMALA_RS33660 b281ee91682bc578dedc52dcc7ae0701 304 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 20 212 1.1E-10 T 29-03-2018 IPR008775 Phytanoyl-CoA dioxygenase SMALA_RS33660 b281ee91682bc578dedc52dcc7ae0701 304 SUPERFAMILY SSF51197 11 248 7.55E-29 T 29-03-2018 SMALA_RS04100 5df2935b8356cd3df5518b49d7641a37 185 Gene3D G3DSA:3.40.630.30 100 167 4.5E-14 T 29-03-2018 SMALA_RS04100 5df2935b8356cd3df5518b49d7641a37 185 SUPERFAMILY SSF55729 14 164 1.06E-26 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS04100 5df2935b8356cd3df5518b49d7641a37 185 Pfam PF00583 Acetyltransferase (GNAT) family 69 151 2.8E-11 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SMALA_RS04100 5df2935b8356cd3df5518b49d7641a37 185 Gene3D G3DSA:3.40.630.30 8 99 2.3E-14 T 29-03-2018 SMALA_RS33915 cb1c743d13e7046d8fe16ff55b2da26e 373 Gene3D G3DSA:3.40.50.150 37 174 8.2E-29 T 29-03-2018 SMALA_RS33915 cb1c743d13e7046d8fe16ff55b2da26e 373 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 66 144 6.0E-8 T 29-03-2018 SMALA_RS33915 cb1c743d13e7046d8fe16ff55b2da26e 373 SUPERFAMILY SSF53335 45 177 2.92E-25 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS40975 6ac5445d6dbfe821998390dcc3c88b53 378 SMART SM00825 Beta-ketoacyl synthase 3 375 5.5E-11 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMALA_RS40975 6ac5445d6dbfe821998390dcc3c88b53 378 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 65 216 1.8E-12 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SMALA_RS40975 6ac5445d6dbfe821998390dcc3c88b53 378 SUPERFAMILY SSF53901 184 374 3.26E-43 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS40975 6ac5445d6dbfe821998390dcc3c88b53 378 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 221 333 5.2E-24 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SMALA_RS40975 6ac5445d6dbfe821998390dcc3c88b53 378 Gene3D G3DSA:3.40.47.10 229 376 5.9E-35 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS40975 6ac5445d6dbfe821998390dcc3c88b53 378 SUPERFAMILY SSF53901 3 216 1.62E-28 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS40975 6ac5445d6dbfe821998390dcc3c88b53 378 Gene3D G3DSA:3.40.47.10 1 216 8.3E-27 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMALA_RS30510 9d317be56308adb1a7f3387def36e304 83 Gene3D G3DSA:3.30.70.930 1 82 1.6E-9 T 29-03-2018 IPR029756 MTH1187/YkoF-like SMALA_RS30510 9d317be56308adb1a7f3387def36e304 83 SUPERFAMILY SSF89957 3 77 2.83E-7 T 29-03-2018 IPR029756 MTH1187/YkoF-like SMALA_RS09690 82009b5d37a068d69f7e46b143f03d16 180 SUPERFAMILY SSF160379 1 179 1.44E-48 T 29-03-2018 SMALA_RS09690 82009b5d37a068d69f7e46b143f03d16 180 Gene3D G3DSA:3.30.70.1260 97 178 4.5E-27 T 29-03-2018 SMALA_RS09690 82009b5d37a068d69f7e46b143f03d16 180 PIRSF PIRSF008502 1 180 2.5E-45 T 29-03-2018 IPR012545 Protein of unknown function DUF1697 SMALA_RS09690 82009b5d37a068d69f7e46b143f03d16 180 Pfam PF08002 Protein of unknown function (DUF1697) 1 138 4.5E-39 T 29-03-2018 IPR012545 Protein of unknown function DUF1697 SMALA_RS09690 82009b5d37a068d69f7e46b143f03d16 180 Gene3D G3DSA:3.30.70.1280 2 87 3.6E-27 T 29-03-2018 SMALA_RS02815 52d249b83cadb6cba66553a8f50e9440 300 SUPERFAMILY SSF56601 10 152 1.36E-32 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMALA_RS02815 52d249b83cadb6cba66553a8f50e9440 300 SUPERFAMILY SSF56601 184 296 1.36E-32 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMALA_RS02815 52d249b83cadb6cba66553a8f50e9440 300 Pfam PF13354 Beta-lactamase enzyme family 28 268 2.1E-41 T 29-03-2018 SMALA_RS02815 52d249b83cadb6cba66553a8f50e9440 300 Gene3D G3DSA:3.40.710.10 1 299 3.3E-33 T 29-03-2018 SMALA_RS43070 5b0e8b3a43135739d19c64344c0c4c5a 225 Gene3D G3DSA:3.40.1350.10 3 137 3.7E-13 T 29-03-2018 SMALA_RS14345 ee9621a9d4c9995e0b7fd643be431690 260 Gene3D G3DSA:3.90.230.10 1 255 4.1E-53 T 29-03-2018 SMALA_RS14345 ee9621a9d4c9995e0b7fd643be431690 260 PRINTS PR00599 Methionine aminopeptidase-1 signature 197 209 4.4E-14 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 SMALA_RS14345 ee9621a9d4c9995e0b7fd643be431690 260 PRINTS PR00599 Methionine aminopeptidase-1 signature 95 111 4.4E-14 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 SMALA_RS14345 ee9621a9d4c9995e0b7fd643be431690 260 PRINTS PR00599 Methionine aminopeptidase-1 signature 73 86 4.4E-14 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 SMALA_RS14345 ee9621a9d4c9995e0b7fd643be431690 260 PRINTS PR00599 Methionine aminopeptidase-1 signature 166 178 4.4E-14 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 SMALA_RS14345 ee9621a9d4c9995e0b7fd643be431690 260 Pfam PF00557 Metallopeptidase family M24 17 246 1.6E-32 T 29-03-2018 IPR000994 Peptidase M24 SMALA_RS14345 ee9621a9d4c9995e0b7fd643be431690 260 SUPERFAMILY SSF55920 1 253 6.41E-57 T 29-03-2018 IPR000994 Peptidase M24 SMALA_RS14345 ee9621a9d4c9995e0b7fd643be431690 260 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 2 253 3.2E-61 T 29-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 SMALA_RS14345 ee9621a9d4c9995e0b7fd643be431690 260 Hamap MF_01974 Methionine aminopeptidase [map]. 2 255 28.985 T 29-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 SMALA_RS02090 14a495df2ce7dd24b0f77dad116a336d 125 ProDom PD076485 YNEG CYTOPLASMIC ECS2130 STY1535 3 113 6.0E-27 T 29-03-2018 IPR020378 Protein of unknown function DUF4186 SMALA_RS02090 14a495df2ce7dd24b0f77dad116a336d 125 Pfam PF13811 Domain of unknown function (DUF4186) 7 114 1.8E-44 T 29-03-2018 IPR020378 Protein of unknown function DUF4186 SMALA_RS27855 aa4f70cf7f9fd7c74cda3c1da6677b11 140 SMART SM00960 12 102 9.0E-33 T 29-03-2018 IPR004942 Roadblock/LAMTOR2 domain SMALA_RS27855 aa4f70cf7f9fd7c74cda3c1da6677b11 140 Pfam PF03259 Roadblock/LC7 domain 12 102 5.7E-25 T 29-03-2018 IPR004942 Roadblock/LAMTOR2 domain SMALA_RS27855 aa4f70cf7f9fd7c74cda3c1da6677b11 140 SUPERFAMILY SSF103196 4 128 9.29E-32 T 29-03-2018 SMALA_RS27855 aa4f70cf7f9fd7c74cda3c1da6677b11 140 Gene3D G3DSA:3.30.450.30 7 134 1.5E-44 T 29-03-2018 SMALA_RS30150 49e71e29ce36f6e456afec122b839d21 274 Gene3D G3DSA:3.40.50.300 2 245 6.7E-51 T 29-03-2018 SMALA_RS30150 49e71e29ce36f6e456afec122b839d21 274 Pfam PF00005 ABC transporter 24 174 8.9E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS30150 49e71e29ce36f6e456afec122b839d21 274 SUPERFAMILY SSF52540 7 239 9.09E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS30150 49e71e29ce36f6e456afec122b839d21 274 SMART SM00382 33 224 2.1E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS43190 fed093f8ac71fdf2479a72d2bb7a8641 270 Gene3D G3DSA:1.20.1270.70 58 104 0.015 T 29-03-2018 SMALA_RS43190 fed093f8ac71fdf2479a72d2bb7a8641 270 Gene3D G3DSA:1.20.1270.70 7 57 7.8E-5 T 29-03-2018 SMALA_RS15105 7e9b1931aca32a95e79e51b0c2dc1d6b 563 Pfam PF06271 RDD family 405 555 4.4E-23 T 29-03-2018 IPR010432 RDD SMALA_RS15105 7e9b1931aca32a95e79e51b0c2dc1d6b 563 Pfam PF10708 Protein of unknown function (DUF2510) 15 46 5.9E-10 T 29-03-2018 IPR018929 Domain of unknown function DUF2510 SMALA_RS12915 3d22177a99589495b80a67de5fb5a6cd 334 Gene3D G3DSA:3.40.50.300 120 326 4.9E-31 T 29-03-2018 SMALA_RS12915 3d22177a99589495b80a67de5fb5a6cd 334 Pfam PF02562 PhoH-like protein 123 326 6.4E-95 T 29-03-2018 IPR003714 PhoH-like protein GO:0005524 SMALA_RS12915 3d22177a99589495b80a67de5fb5a6cd 334 SUPERFAMILY SSF52540 122 301 1.05E-40 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS42415 f2ad3a52b9a6a760e54dabe6da30e4fb 309 SUPERFAMILY SSF56219 78 308 9.42E-28 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMALA_RS42415 f2ad3a52b9a6a760e54dabe6da30e4fb 309 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 80 301 8.9E-10 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMALA_RS42415 f2ad3a52b9a6a760e54dabe6da30e4fb 309 Gene3D G3DSA:3.60.10.10 67 309 4.4E-29 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SMALA_RS19420 aa80ca86154639ac45dba2f021cf5292 529 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 10 490 1.9E-174 T 29-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 SMALA_RS19420 aa80ca86154639ac45dba2f021cf5292 529 PIRSF PIRSF006446 3 386 3.5E-119 T 29-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 SMALA_RS19420 aa80ca86154639ac45dba2f021cf5292 529 PIRSF PIRSF006446 391 506 1.8E-25 T 29-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 SMALA_RS01530 36700e2fa5962b4e49da1d30207d25e3 338 Pfam PF03773 Predicted permease 58 333 1.9E-45 T 29-03-2018 IPR005524 Predicted permease DUF318 SMALA_RS18705 a18178d14e74e8c276124eb338f9ce93 140 Gene3D G3DSA:2.40.50.100 64 131 7.8E-23 T 29-03-2018 SMALA_RS18705 a18178d14e74e8c276124eb338f9ce93 140 Pfam PF03459 TOBE domain 4 66 9.8E-15 T 29-03-2018 IPR005116 Transport-associated OB, type 1 SMALA_RS18705 a18178d14e74e8c276124eb338f9ce93 140 Pfam PF03459 TOBE domain 75 136 3.1E-18 T 29-03-2018 IPR005116 Transport-associated OB, type 1 SMALA_RS18705 a18178d14e74e8c276124eb338f9ce93 140 SUPERFAMILY SSF50331 1 69 1.68E-17 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal SMALA_RS18705 a18178d14e74e8c276124eb338f9ce93 140 Gene3D G3DSA:2.40.50.100 1 63 1.4E-19 T 29-03-2018 SMALA_RS18705 a18178d14e74e8c276124eb338f9ce93 140 SUPERFAMILY SSF50331 74 139 7.44E-19 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal SMALA_RS18705 a18178d14e74e8c276124eb338f9ce93 140 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 74 139 1.1E-20 T 29-03-2018 IPR004606 Molybdenum-pterin binding GO:0006810|GO:0030151 SMALA_RS18705 a18178d14e74e8c276124eb338f9ce93 140 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 1 68 2.6E-17 T 29-03-2018 IPR004606 Molybdenum-pterin binding GO:0006810|GO:0030151 SMALA_RS06405 8036221cfa573b34783e527e1e82b7b2 87 SUPERFAMILY SSF47336 11 84 1.14E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS06405 8036221cfa573b34783e527e1e82b7b2 87 Pfam PF00550 Phosphopantetheine attachment site 13 78 1.8E-7 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS06405 8036221cfa573b34783e527e1e82b7b2 87 Gene3D G3DSA:1.10.1200.10 8 87 4.2E-14 T 29-03-2018 SMALA_RS41855 c0ad329e96d6a0f7862e3f0993758467 231 SUPERFAMILY SSF52821 113 210 4.32E-25 T 29-03-2018 IPR001763 Rhodanese-like domain SMALA_RS41855 c0ad329e96d6a0f7862e3f0993758467 231 SUPERFAMILY SSF54909 4 79 1.65E-11 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel SMALA_RS41855 c0ad329e96d6a0f7862e3f0993758467 231 SMART SM00450 114 208 4.8E-16 T 29-03-2018 IPR001763 Rhodanese-like domain SMALA_RS41855 c0ad329e96d6a0f7862e3f0993758467 231 Pfam PF00581 Rhodanese-like domain 115 204 8.0E-11 T 29-03-2018 IPR001763 Rhodanese-like domain SMALA_RS41855 c0ad329e96d6a0f7862e3f0993758467 231 Gene3D G3DSA:3.40.250.10 102 217 7.5E-21 T 29-03-2018 IPR001763 Rhodanese-like domain SMALA_RS41855 c0ad329e96d6a0f7862e3f0993758467 231 Gene3D G3DSA:3.30.70.100 2 101 2.1E-10 T 29-03-2018 SMALA_RS41855 c0ad329e96d6a0f7862e3f0993758467 231 Pfam PF03992 Antibiotic biosynthesis monooxygenase 6 71 1.7E-8 T 29-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain SMALA_RS07825 e824df3bb69d396c3a0e55cc03bc8d1c 110 Gene3D G3DSA:1.10.287.1060 2 96 5.4E-4 T 29-03-2018 SMALA_RS28285 9faa12578adcf49e8697b15673b88ea1 558 SUPERFAMILY SSF52467 163 355 1.14E-38 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain SMALA_RS28285 9faa12578adcf49e8697b15673b88ea1 558 SUPERFAMILY SSF52518 367 531 1.79E-41 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold SMALA_RS28285 9faa12578adcf49e8697b15673b88ea1 558 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 200 330 1.1E-33 T 29-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 SMALA_RS28285 9faa12578adcf49e8697b15673b88ea1 558 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 9 179 1.2E-43 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 SMALA_RS28285 9faa12578adcf49e8697b15673b88ea1 558 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 392 528 1.1E-31 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 SMALA_RS28285 9faa12578adcf49e8697b15673b88ea1 558 Gene3D G3DSA:3.40.50.970 1 198 1.6E-41 T 29-03-2018 SMALA_RS28285 9faa12578adcf49e8697b15673b88ea1 558 SUPERFAMILY SSF52518 8 189 1.96E-39 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold SMALA_RS28285 9faa12578adcf49e8697b15673b88ea1 558 Gene3D G3DSA:3.40.50.1220 199 369 5.5E-38 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain SMALA_RS28285 9faa12578adcf49e8697b15673b88ea1 558 Gene3D G3DSA:3.40.50.970 370 531 5.2E-32 T 29-03-2018 SMALA_RS41500 bb7c4eaa272f5944a9b073f26c159e01 148 Pfam PF08592 Domain of unknown function (DUF1772) 18 146 2.7E-16 T 29-03-2018 IPR013901 Anthrone oxygenase SMALA_RS34845 bc1865584618f5b9e94e73daa8c50a18 118 Pfam PF05331 Protein of unknown function (DUF742) 11 118 4.7E-29 T 29-03-2018 IPR007995 Protein of unknown function DUF742 SMALA_RS34845 bc1865584618f5b9e94e73daa8c50a18 118 Gene3D G3DSA:1.10.10.10 4 103 9.8E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS20990 0be18ee4114cef5dfb626c00f027c82d 371 Gene3D G3DSA:3.20.20.70 75 305 2.6E-25 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS20990 0be18ee4114cef5dfb626c00f027c82d 371 SUPERFAMILY SSF102114 84 343 6.67E-37 T 29-03-2018 SMALA_RS20990 0be18ee4114cef5dfb626c00f027c82d 371 Pfam PF04055 Radical SAM superfamily 89 235 3.9E-16 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 SMALA_RS38795 36d84ca24d151942b940df91fa6dde28 498 SUPERFAMILY SSF51905 277 394 6.65E-61 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS38795 36d84ca24d151942b940df91fa6dde28 498 SUPERFAMILY SSF51905 7 170 6.65E-61 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS38795 36d84ca24d151942b940df91fa6dde28 498 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 296 312 6.6E-46 T 29-03-2018 SMALA_RS38795 36d84ca24d151942b940df91fa6dde28 498 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 332 348 6.6E-46 T 29-03-2018 SMALA_RS38795 36d84ca24d151942b940df91fa6dde28 498 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 149 164 6.6E-46 T 29-03-2018 SMALA_RS38795 36d84ca24d151942b940df91fa6dde28 498 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 8 30 6.6E-46 T 29-03-2018 SMALA_RS38795 36d84ca24d151942b940df91fa6dde28 498 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 314 332 6.6E-46 T 29-03-2018 SMALA_RS38795 36d84ca24d151942b940df91fa6dde28 498 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 281 296 6.6E-46 T 29-03-2018 SMALA_RS38795 36d84ca24d151942b940df91fa6dde28 498 Gene3D G3DSA:3.50.50.60 3 393 1.4E-63 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS38795 36d84ca24d151942b940df91fa6dde28 498 Pfam PF01494 FAD binding domain 7 345 3.1E-84 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 SMALA_RS35900 df58ff4aee4a98230635f8c4f2b96e1f 1213 Pfam PF02514 CobN/Magnesium Chelatase 100 1192 0.0 T 29-03-2018 IPR003672 CobN/magnesium chelatase GO:0009058 SMALA_RS35900 df58ff4aee4a98230635f8c4f2b96e1f 1213 TIGRFAM TIGR02257 cobalto_cobN: cobaltochelatase, CobN subunit 41 1205 0.0 T 29-03-2018 IPR011953 Cobaltochelatase, CobN subunit GO:0009236|GO:0051116 SMALA_RS16910 408cdaae06fd892ffba499c1f8b37f60 381 Pfam PF07728 AAA domain (dynein-related subfamily) 99 237 6.1E-35 T 29-03-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 SMALA_RS16910 408cdaae06fd892ffba499c1f8b37f60 381 Gene3D G3DSA:3.40.50.300 74 277 1.1E-16 T 29-03-2018 SMALA_RS16910 408cdaae06fd892ffba499c1f8b37f60 381 SUPERFAMILY SSF52540 77 356 1.54E-19 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS08620 58165542b0da51c6cd5f94427ea41da7 96 Pfam PF05121 Gas vesicle protein K 9 92 4.8E-36 T 29-03-2018 IPR007805 Gas vesicle protein GvpK GO:0031412 SMALA_RS01915 245b098d7a1437a0908cbd68914629c1 255 PIRSF PIRSF029958 1 255 1.1E-115 T 29-03-2018 IPR008701 Necrosis inducing protein SMALA_RS01915 245b098d7a1437a0908cbd68914629c1 255 Pfam PF05630 Necrosis inducing protein (NPP1) 44 243 5.1E-63 T 29-03-2018 IPR008701 Necrosis inducing protein SMALA_RS38705 8e3c7295f749418af05832f8a241d29b 915 SUPERFAMILY SSF53822 502 876 7.06E-11 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SMALA_RS38705 8e3c7295f749418af05832f8a241d29b 915 Gene3D G3DSA:3.40.50.2300 467 876 1.5E-12 T 29-03-2018 SMALA_RS04335 ce50d49346bfa36ae3ffe08048ffeab9 500 Pfam PF00561 alpha/beta hydrolase fold 94 453 1.9E-26 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS04335 ce50d49346bfa36ae3ffe08048ffeab9 500 Gene3D G3DSA:3.40.50.1820 62 479 2.1E-41 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS04335 ce50d49346bfa36ae3ffe08048ffeab9 500 SUPERFAMILY SSF53474 77 138 6.77E-29 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS04335 ce50d49346bfa36ae3ffe08048ffeab9 500 SUPERFAMILY SSF53474 174 343 6.77E-29 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS04335 ce50d49346bfa36ae3ffe08048ffeab9 500 SUPERFAMILY SSF53474 413 462 6.77E-29 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS29765 b9cc1bd824cf6534f19a2c27d1ad398d 478 TIGRFAM TIGR03851 chitin_NgcE: carbohydrate ABC transporter, N-acetylglucosamine/diacetylchitobiose-binding protein 25 475 1.5E-187 T 29-03-2018 IPR022386 Carbohydrate ABC transporter, N-acetylglucosamine/diacetylchitobiose-binding protein SMALA_RS29765 b9cc1bd824cf6534f19a2c27d1ad398d 478 Pfam PF13416 Bacterial extracellular solute-binding protein 83 388 5.5E-24 T 29-03-2018 SMALA_RS29765 b9cc1bd824cf6534f19a2c27d1ad398d 478 SUPERFAMILY SSF53850 31 475 9.24E-59 T 29-03-2018 SMALA_RS29765 b9cc1bd824cf6534f19a2c27d1ad398d 478 Gene3D G3DSA:3.40.190.10 182 477 1.8E-37 T 29-03-2018 SMALA_RS28060 4e9af79edb840f5c6ddb9c0df00a147a 328 Pfam PF00296 Luciferase-like monooxygenase 18 263 2.1E-36 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS28060 4e9af79edb840f5c6ddb9c0df00a147a 328 SUPERFAMILY SSF51679 7 327 4.97E-58 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS28060 4e9af79edb840f5c6ddb9c0df00a147a 328 Gene3D G3DSA:3.20.20.30 3 328 5.8E-67 T 29-03-2018 SMALA_RS01820 b45185a7badaa6e41689183a1ab9d2b1 372 Gene3D G3DSA:3.20.20.70 1 356 1.9E-102 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS01820 b45185a7badaa6e41689183a1ab9d2b1 372 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 250 256 - T 29-03-2018 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 SMALA_RS01820 b45185a7badaa6e41689183a1ab9d2b1 372 PIRSF PIRSF000138 1 356 2.7E-123 T 29-03-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 SMALA_RS01820 b45185a7badaa6e41689183a1ab9d2b1 372 Pfam PF01070 FMN-dependent dehydrogenase 12 353 1.4E-121 T 29-03-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 SMALA_RS01820 b45185a7badaa6e41689183a1ab9d2b1 372 SUPERFAMILY SSF51395 3 352 9.77E-93 T 29-03-2018 SMALA_RS23405 9700935378832d5856c2d708dd615b81 98 Pfam PF08734 GYD domain 4 92 4.0E-31 T 29-03-2018 IPR014845 Uncharacterised protein GYD SMALA_RS23405 9700935378832d5856c2d708dd615b81 98 Gene3D G3DSA:3.30.70.920 5 83 7.8E-4 T 29-03-2018 SMALA_RS28835 ff7d18dcde4d68bae1d08e0f28584a80 573 SUPERFAMILY SSF51905 3 87 4.33E-41 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS28835 ff7d18dcde4d68bae1d08e0f28584a80 573 SUPERFAMILY SSF51905 300 395 4.33E-41 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS28835 ff7d18dcde4d68bae1d08e0f28584a80 573 SUPERFAMILY SSF51905 120 206 4.33E-41 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS28835 ff7d18dcde4d68bae1d08e0f28584a80 573 Gene3D G3DSA:3.50.50.60 2 187 1.5E-10 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS28835 ff7d18dcde4d68bae1d08e0f28584a80 573 Pfam PF01494 FAD binding domain 3 374 1.3E-40 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 SMALA_RS28835 ff7d18dcde4d68bae1d08e0f28584a80 573 Gene3D G3DSA:3.30.9.10 188 396 4.2E-35 T 29-03-2018 SMALA_RS28835 ff7d18dcde4d68bae1d08e0f28584a80 573 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 8.5E-26 T 29-03-2018 SMALA_RS28835 ff7d18dcde4d68bae1d08e0f28584a80 573 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 185 200 8.5E-26 T 29-03-2018 SMALA_RS28835 ff7d18dcde4d68bae1d08e0f28584a80 573 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 328 344 8.5E-26 T 29-03-2018 SMALA_RS28835 ff7d18dcde4d68bae1d08e0f28584a80 573 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 346 364 8.5E-26 T 29-03-2018 SMALA_RS28835 ff7d18dcde4d68bae1d08e0f28584a80 573 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 313 328 8.5E-26 T 29-03-2018 SMALA_RS41020 d4a483853158ab43e1fbc03fda9bba1f 183 Gene3D G3DSA:1.20.120.450 10 183 2.1E-29 T 29-03-2018 SMALA_RS41020 d4a483853158ab43e1fbc03fda9bba1f 183 Pfam PF04978 Protein of unknown function (DUF664) 34 179 2.1E-41 T 29-03-2018 IPR007061 Protein of unknown function DUF664 SMALA_RS41020 d4a483853158ab43e1fbc03fda9bba1f 183 SUPERFAMILY SSF109854 15 178 4.12E-37 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes SMALA_RS22700 409f0f091fb9c0de9fd2e7354449553a 136 Pfam PF01740 STAS domain 22 101 3.6E-7 T 29-03-2018 IPR002645 STAS domain SMALA_RS22700 409f0f091fb9c0de9fd2e7354449553a 136 SUPERFAMILY SSF52091 10 101 2.94E-17 T 29-03-2018 IPR002645 STAS domain SMALA_RS22700 409f0f091fb9c0de9fd2e7354449553a 136 Gene3D G3DSA:3.30.750.24 6 119 7.9E-12 T 29-03-2018 IPR002645 STAS domain SMALA_RS28240 be0d075d7f61b4fa3e0e06d5612fae66 185 Hamap MF_00040 Ribosome-recycling factor [frr]. 3 185 26.655 T 29-03-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 SMALA_RS28240 be0d075d7f61b4fa3e0e06d5612fae66 185 SUPERFAMILY SSF55194 3 184 6.93E-66 T 29-03-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 SMALA_RS28240 be0d075d7f61b4fa3e0e06d5612fae66 185 Pfam PF01765 Ribosome recycling factor 21 183 2.2E-57 T 29-03-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 SMALA_RS28240 be0d075d7f61b4fa3e0e06d5612fae66 185 TIGRFAM TIGR00496 frr: ribosome recycling factor 10 185 2.3E-61 T 29-03-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 SMALA_RS28240 be0d075d7f61b4fa3e0e06d5612fae66 185 Gene3D G3DSA:1.10.132.20 2 73 8.8E-10 T 29-03-2018 SMALA_RS28240 be0d075d7f61b4fa3e0e06d5612fae66 185 Gene3D G3DSA:1.10.132.20 74 184 1.3E-35 T 29-03-2018 SMALA_RS26575 8e6528c51bf825e7d9bfbd376a1d2952 236 Gene3D G3DSA:3.40.50.150 58 225 1.2E-20 T 29-03-2018 SMALA_RS26575 8e6528c51bf825e7d9bfbd376a1d2952 236 SUPERFAMILY SSF53335 15 212 1.02E-21 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS41585 a2e085c41b3ea24792431dd7e4ef9392 391 Pfam PF06500 Alpha/beta hydrolase of unknown function (DUF1100) 76 249 8.7E-8 T 29-03-2018 IPR010520 UPF0255 family SMALA_RS41585 a2e085c41b3ea24792431dd7e4ef9392 391 Gene3D G3DSA:1.20.1440.110 7 123 7.0E-24 T 29-03-2018 SMALA_RS41585 a2e085c41b3ea24792431dd7e4ef9392 391 SUPERFAMILY SSF53474 8 382 1.28E-59 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS41585 a2e085c41b3ea24792431dd7e4ef9392 391 Gene3D G3DSA:3.40.50.1820 124 390 3.4E-30 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS22520 93e3e20e869df2b1b7152e664a1b920f 720 Pfam PF02585 GlcNAc-PI de-N-acetylase 80 292 8.9E-24 T 29-03-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 SMALA_RS22520 93e3e20e869df2b1b7152e664a1b920f 720 SUPERFAMILY SSF102588 184 341 1.31E-19 T 29-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 SMALA_RS22520 93e3e20e869df2b1b7152e664a1b920f 720 SUPERFAMILY SSF102588 79 151 1.31E-19 T 29-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 SMALA_RS22520 93e3e20e869df2b1b7152e664a1b920f 720 Gene3D G3DSA:3.40.50.10320 56 372 5.1E-34 T 29-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 SMALA_RS22520 93e3e20e869df2b1b7152e664a1b920f 720 SUPERFAMILY SSF89372 379 609 1.83E-16 T 29-03-2018 SMALA_RS22520 93e3e20e869df2b1b7152e664a1b920f 720 Gene3D G3DSA:2.120.10.70 373 622 3.3E-28 T 29-03-2018 SMALA_RS09205 5df5c2ba0d121e3e0cf534295ce89611 278 Pfam PF01903 CbiX 144 246 9.9E-19 T 29-03-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 SMALA_RS09205 5df5c2ba0d121e3e0cf534295ce89611 278 Pfam PF01903 CbiX 13 116 3.8E-11 T 29-03-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 SMALA_RS09205 5df5c2ba0d121e3e0cf534295ce89611 278 Gene3D G3DSA:3.40.50.1400 2 125 5.8E-20 T 29-03-2018 SMALA_RS09205 5df5c2ba0d121e3e0cf534295ce89611 278 Gene3D G3DSA:3.40.50.1400 128 256 5.1E-28 T 29-03-2018 SMALA_RS09205 5df5c2ba0d121e3e0cf534295ce89611 278 SUPERFAMILY SSF53800 5 253 1.85E-39 T 29-03-2018 SMALA_RS39220 2bec120b74b4ed14a3b391425a7b2d21 477 Pfam PF04820 Tryptophan halogenase 11 98 4.0E-19 T 29-03-2018 IPR006905 Flavin-dependent halogenase SMALA_RS39220 2bec120b74b4ed14a3b391425a7b2d21 477 Pfam PF04820 Tryptophan halogenase 101 391 3.4E-56 T 29-03-2018 IPR006905 Flavin-dependent halogenase SMALA_RS39220 2bec120b74b4ed14a3b391425a7b2d21 477 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 300 315 1.0E-6 T 29-03-2018 SMALA_RS39220 2bec120b74b4ed14a3b391425a7b2d21 477 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 11 33 1.0E-6 T 29-03-2018 SMALA_RS39220 2bec120b74b4ed14a3b391425a7b2d21 477 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 164 179 1.0E-6 T 29-03-2018 SMALA_RS39220 2bec120b74b4ed14a3b391425a7b2d21 477 SUPERFAMILY SSF51905 287 387 9.03E-48 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS39220 2bec120b74b4ed14a3b391425a7b2d21 477 SUPERFAMILY SSF51905 10 185 9.03E-48 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS39220 2bec120b74b4ed14a3b391425a7b2d21 477 Gene3D G3DSA:3.50.50.60 4 399 1.3E-47 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS17890 12f09c16ae353f8ac9cf47a8639d9567 355 Pfam PF06250 Protein of unknown function (DUF1016) 27 328 3.6E-104 T 29-03-2018 IPR009362 Protein of unknown function DUF1016 SMALA_RS25430 5923f87dfd27afa6d9a1af0dedf1219b 84 Gene3D G3DSA:3.30.2310.20 2 84 5.1E-25 T 29-03-2018 SMALA_RS25430 5923f87dfd27afa6d9a1af0dedf1219b 84 SUPERFAMILY SSF143011 3 83 2.75E-27 T 29-03-2018 IPR035095 Toxin RelE-like domain SMALA_RS25430 5923f87dfd27afa6d9a1af0dedf1219b 84 Pfam PF06769 YoeB-like toxin of bacterial type II toxin-antitoxin system 5 84 1.3E-41 T 29-03-2018 IPR009614 Toxin YoeB GO:0004519|GO:0006401 SMALA_RS25430 5923f87dfd27afa6d9a1af0dedf1219b 84 TIGRFAM TIGR02116 toxin_Txe_YoeB: addiction module toxin, Txe/YoeB family 5 84 2.6E-39 T 29-03-2018 IPR009614 Toxin YoeB GO:0004519|GO:0006401 SMALA_RS19015 3132ab098eb738997f1dd564ae9fbe45 211 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 3 209 2.6E-76 T 29-03-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 SMALA_RS19015 3132ab098eb738997f1dd564ae9fbe45 211 SUPERFAMILY SSF53271 3 208 1.31E-63 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like SMALA_RS19015 3132ab098eb738997f1dd564ae9fbe45 211 Gene3D G3DSA:3.40.50.2020 1 208 6.4E-66 T 29-03-2018 SMALA_RS19015 3132ab098eb738997f1dd564ae9fbe45 211 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 2 210 43.581 T 29-03-2018 IPR034332 Uracil phosphoribosyltransferase, bacterial-type KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 SMALA_RS19015 3132ab098eb738997f1dd564ae9fbe45 211 Pfam PF14681 Uracil phosphoribosyltransferase 5 209 3.9E-65 T 29-03-2018 SMALA_RS27790 0a622c5b80f0fcef46fbaf81ced558b4 40 Gene3D G3DSA:1.20.5.440 2 33 1.9E-4 T 29-03-2018 SMALA_RS03685 b297c0fa795f6d785b13d0649a1fc399 268 Gene3D G3DSA:1.10.12.10 226 268 2.7E-16 T 29-03-2018 IPR014748 Crontonase, C-terminal SMALA_RS03685 b297c0fa795f6d785b13d0649a1fc399 268 Gene3D G3DSA:3.90.226.10 4 225 5.1E-66 T 29-03-2018 SMALA_RS03685 b297c0fa795f6d785b13d0649a1fc399 268 Pfam PF00378 Enoyl-CoA hydratase/isomerase 16 266 1.7E-54 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 SMALA_RS03685 b297c0fa795f6d785b13d0649a1fc399 268 SUPERFAMILY SSF52096 4 266 4.98E-80 T 29-03-2018 IPR029045 ClpP/crotonase-like domain SMALA_RS25385 5e48f0731be45f86f1f5d820a58bf26d 351 Pfam PF01471 Putative peptidoglycan binding domain 120 166 1.1E-8 T 29-03-2018 IPR002477 Peptidoglycan binding-like SMALA_RS25385 5e48f0731be45f86f1f5d820a58bf26d 351 Gene3D G3DSA:1.10.101.10 109 172 2.0E-13 T 29-03-2018 IPR002477 Peptidoglycan binding-like SMALA_RS25385 5e48f0731be45f86f1f5d820a58bf26d 351 SUPERFAMILY SSF47090 109 170 3.4E-12 T 29-03-2018 IPR002477 Peptidoglycan binding-like SMALA_RS38970 b127fbf68889411e11f154753756215a 422 SUPERFAMILY SSF53474 116 264 4.06E-11 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS38970 b127fbf68889411e11f154753756215a 422 SUPERFAMILY SSF53474 316 388 4.06E-11 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS38970 b127fbf68889411e11f154753756215a 422 Gene3D G3DSA:3.40.50.1820 95 418 1.7E-6 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS39605 66ac213b19ea5f6fa7b3cbe0a86cc8eb 291 Gene3D G3DSA:3.40.50.720 1 286 1.4E-20 T 29-03-2018 SMALA_RS39605 66ac213b19ea5f6fa7b3cbe0a86cc8eb 291 Pfam PF13460 NAD(P)H-binding 8 190 1.4E-17 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS39605 66ac213b19ea5f6fa7b3cbe0a86cc8eb 291 SUPERFAMILY SSF51735 2 256 1.83E-37 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS38350 9771ae1937f7f091926cf54429f4f727 327 Pfam PF00248 Aldo/keto reductase family 16 311 1.0E-60 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS38350 9771ae1937f7f091926cf54429f4f727 327 SUPERFAMILY SSF51430 1 319 1.09E-78 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS38350 9771ae1937f7f091926cf54429f4f727 327 Gene3D G3DSA:3.20.20.100 1 325 3.1E-76 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS38485 650771ad759dbbda3e1554dcab039e5c 331 Pfam PF03756 A-factor biosynthesis hotdog domain 191 318 3.6E-21 T 29-03-2018 IPR005509 A-factor biosynthesis hotdog domain SMALA_RS38485 650771ad759dbbda3e1554dcab039e5c 331 Pfam PF03756 A-factor biosynthesis hotdog domain 14 150 4.9E-20 T 29-03-2018 IPR005509 A-factor biosynthesis hotdog domain SMALA_RS38485 650771ad759dbbda3e1554dcab039e5c 331 Gene3D G3DSA:3.10.129.10 19 160 0.053 T 29-03-2018 SMALA_RS38485 650771ad759dbbda3e1554dcab039e5c 331 Gene3D G3DSA:3.10.129.10 207 326 2.1E-6 T 29-03-2018 SMALA_RS38485 650771ad759dbbda3e1554dcab039e5c 331 SUPERFAMILY SSF54637 211 319 7.46E-5 T 29-03-2018 IPR029069 HotDog domain SMALA_RS37015 60680f106cf54c29b6d38a849732be1e 135 Pfam PF04965 Gene 25-like lysozyme 27 116 2.4E-23 T 29-03-2018 IPR007048 GpW/Gp25/anti-adapter protein IraD SMALA_RS37015 60680f106cf54c29b6d38a849732be1e 135 SUPERFAMILY SSF160719 22 129 4.45E-33 T 29-03-2018 SMALA_RS37015 60680f106cf54c29b6d38a849732be1e 135 Gene3D G3DSA:3.10.450.40 1 131 8.2E-42 T 29-03-2018 SMALA_RS31115 dbe711b46b9a6abd1fd1ce0b261e016c 221 Pfam PF09335 SNARE associated Golgi protein 41 169 1.4E-11 T 29-03-2018 IPR032816 SNARE associated Golgi protein SMALA_RS35710 0765a66aba697f75131e73247320a587 332 Gene3D G3DSA:3.40.50.1980 53 178 9.5E-25 T 29-03-2018 SMALA_RS35710 0765a66aba697f75131e73247320a587 332 Pfam PF01497 Periplasmic binding protein 72 308 3.9E-27 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 SMALA_RS35710 0765a66aba697f75131e73247320a587 332 SUPERFAMILY SSF53807 50 318 1.26E-55 T 29-03-2018 SMALA_RS35710 0765a66aba697f75131e73247320a587 332 Gene3D G3DSA:3.40.50.1980 179 332 5.4E-31 T 29-03-2018 SMALA_RS07760 4f78f520e581a90ab9dce67a8bceb2ac 354 SUPERFAMILY SSF102114 117 322 3.61E-7 T 29-03-2018 SMALA_RS07760 4f78f520e581a90ab9dce67a8bceb2ac 354 Gene3D G3DSA:3.20.20.70 112 331 2.6E-5 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS07675 97121b5dd8a04d6171c4469935437326 303 Pfam PF00482 Type II secretion system (T2SS), protein F 116 239 6.8E-11 T 29-03-2018 IPR018076 Type II secretion system F domain SMALA_RS29505 d551d080581b21b2c16191650101ac39 137 SUPERFAMILY SSF75169 11 132 1.68E-9 T 29-03-2018 IPR027396 DsrEFH-like SMALA_RS29505 d551d080581b21b2c16191650101ac39 137 Gene3D G3DSA:3.40.1260.10 9 133 6.3E-14 T 29-03-2018 SMALA_RS02875 8eae9c2fea00ace033c0d875dfc7524e 215 Gene3D G3DSA:3.40.50.720 2 212 2.1E-26 T 29-03-2018 SMALA_RS02875 8eae9c2fea00ace033c0d875dfc7524e 215 SUPERFAMILY SSF51735 4 208 2.09E-29 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS02875 8eae9c2fea00ace033c0d875dfc7524e 215 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 4 94 1.2E-12 T 29-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal SMALA_RS04280 e7d9d0c0dad127a9da471528ece885c3 214 PIRSF PIRSF006324 1 212 1.1E-51 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 SMALA_RS04280 e7d9d0c0dad127a9da471528ece885c3 214 Pfam PF01810 LysE type translocator 16 209 5.8E-29 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 SMALA_RS05075 750f299b3f05b2c8f22cceca835c9461 126 SUPERFAMILY SSF54593 1 120 1.83E-14 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS05075 750f299b3f05b2c8f22cceca835c9461 126 Gene3D G3DSA:3.10.180.10 2 123 5.3E-19 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS05075 750f299b3f05b2c8f22cceca835c9461 126 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 117 3.3E-4 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMALA_RS08325 80ca0197dfb51d651ca8351c64a5d147 367 SUPERFAMILY SSF55729 146 322 6.36E-21 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS08325 80ca0197dfb51d651ca8351c64a5d147 367 Pfam PF13480 Acetyltransferase (GNAT) domain 160 301 1.3E-40 T 29-03-2018 SMALA_RS08325 80ca0197dfb51d651ca8351c64a5d147 367 Gene3D G3DSA:3.40.630.30 102 322 1.8E-27 T 29-03-2018 SMALA_RS00375 9c84246adb9ae7fac721cede084b9f20 56 TIGRFAM TIGR03898 lanti_MRSA_kill: type 2 lantibiotic, mersacidin/lichenicidin family 4 31 8.5E-8 T 29-03-2018 IPR027635 Type 2 lantibiotic, leader peptide domain GO:0042742 SMALA_RS00335 5c0095680c92817300a1c088f30b29e9 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 71 3.3E-13 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS00335 5c0095680c92817300a1c088f30b29e9 196 Gene3D G3DSA:1.10.357.10 74 196 2.6E-14 T 29-03-2018 SMALA_RS00335 5c0095680c92817300a1c088f30b29e9 196 Gene3D G3DSA:1.10.260.40 50 73 3.2E-10 T 29-03-2018 SMALA_RS00335 5c0095680c92817300a1c088f30b29e9 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 39 2.8E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS00335 5c0095680c92817300a1c088f30b29e9 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 2.8E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS00335 5c0095680c92817300a1c088f30b29e9 196 SUPERFAMILY SSF46689 13 95 2.29E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS00335 5c0095680c92817300a1c088f30b29e9 196 SUPERFAMILY SSF48498 92 195 3.39E-12 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS00335 5c0095680c92817300a1c088f30b29e9 196 Gene3D G3DSA:1.10.10.60 3 49 3.5E-14 T 29-03-2018 SMALA_RS34980 33d0bc6670f80fb0132d2f63b47833a0 357 Pfam PF04679 ATP dependent DNA ligase C terminal region 215 329 4.6E-17 T 29-03-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 SMALA_RS34980 33d0bc6670f80fb0132d2f63b47833a0 357 Pfam PF01068 ATP dependent DNA ligase domain 11 197 8.5E-38 T 29-03-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 SMALA_RS34980 33d0bc6670f80fb0132d2f63b47833a0 357 SUPERFAMILY SSF56091 6 197 1.3E-42 T 29-03-2018 SMALA_RS34980 33d0bc6670f80fb0132d2f63b47833a0 357 Gene3D G3DSA:3.30.470.30 2 136 8.8E-31 T 29-03-2018 SMALA_RS34980 33d0bc6670f80fb0132d2f63b47833a0 357 SUPERFAMILY SSF50249 200 259 7.71E-14 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMALA_RS34980 33d0bc6670f80fb0132d2f63b47833a0 357 SUPERFAMILY SSF50249 294 336 7.71E-14 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMALA_RS34980 33d0bc6670f80fb0132d2f63b47833a0 357 Gene3D G3DSA:3.30.1490.70 137 197 8.8E-12 T 29-03-2018 SMALA_RS34980 33d0bc6670f80fb0132d2f63b47833a0 357 ProSitePatterns PS00697 ATP-dependent DNA ligase AMP-binding site. 27 35 - T 29-03-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 SMALA_RS34980 33d0bc6670f80fb0132d2f63b47833a0 357 Gene3D G3DSA:2.40.50.140 198 344 1.3E-30 T 29-03-2018 SMALA_RS16295 d85eaa5e49fed169eb438281f08e4197 425 Gene3D G3DSA:2.40.440.10 251 394 4.7E-27 T 29-03-2018 SMALA_RS16295 d85eaa5e49fed169eb438281f08e4197 425 SUPERFAMILY SSF141523 260 392 3.27E-21 T 29-03-2018 SMALA_RS16295 d85eaa5e49fed169eb438281f08e4197 425 Pfam PF03734 L,D-transpeptidase catalytic domain 258 392 4.1E-13 T 29-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 SMALA_RS16295 d85eaa5e49fed169eb438281f08e4197 425 Gene3D G3DSA:2.60.40.1220 59 150 0.42 T 29-03-2018 SMALA_RS37885 a13a0f5224bfcbec20c07ec6baada96e 262 SUPERFAMILY SSF49899 114 242 7.12E-5 T 29-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain SMALA_RS37885 a13a0f5224bfcbec20c07ec6baada96e 262 Gene3D G3DSA:2.60.120.260 42 259 8.5E-22 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS04780 60a274aedab4821b690ac2284ac8b3a1 282 SUPERFAMILY SSF53474 6 280 5.05E-31 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS04780 60a274aedab4821b690ac2284ac8b3a1 282 Pfam PF12697 Alpha/beta hydrolase family 8 276 5.2E-22 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS04780 60a274aedab4821b690ac2284ac8b3a1 282 Gene3D G3DSA:3.40.50.1820 2 280 8.8E-29 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS33460 e3e6276257b572d405a2da570ac576e1 482 SUPERFAMILY SSF52777 26 186 6.23E-24 T 29-03-2018 SMALA_RS33460 e3e6276257b572d405a2da570ac576e1 482 Pfam PF00668 Condensation domain 30 363 3.5E-16 T 29-03-2018 IPR001242 Condensation domain SMALA_RS33460 e3e6276257b572d405a2da570ac576e1 482 Gene3D G3DSA:3.30.559.10 22 219 2.4E-21 T 29-03-2018 SMALA_RS33460 e3e6276257b572d405a2da570ac576e1 482 SUPERFAMILY SSF52777 215 448 1.78E-8 T 29-03-2018 SMALA_RS20390 f642d86ce76fb3426b1e1b60c22cdb75 481 Pfam PF13520 Amino acid permease 61 439 1.2E-41 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMALA_RS20390 f642d86ce76fb3426b1e1b60c22cdb75 481 PIRSF PIRSF006060 42 460 2.6E-55 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMALA_RS16410 34dd4287ebbb05bce089f021626c67e6 477 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 256 263 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 SMALA_RS16410 34dd4287ebbb05bce089f021626c67e6 477 Gene3D G3DSA:3.40.605.10 16 275 1.4E-102 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS16410 34dd4287ebbb05bce089f021626c67e6 477 Pfam PF00171 Aldehyde dehydrogenase family 33 476 3.2E-165 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMALA_RS16410 34dd4287ebbb05bce089f021626c67e6 477 SUPERFAMILY SSF53720 19 476 1.2E-165 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMALA_RS16410 34dd4287ebbb05bce089f021626c67e6 477 Gene3D G3DSA:3.40.309.10 276 466 6.2E-69 T 29-03-2018 SMALA_RS30955 177780a6790fd82916b2fd52a6c5de4f 184 Gene3D G3DSA:3.40.630.30 2 183 2.3E-28 T 29-03-2018 SMALA_RS30955 177780a6790fd82916b2fd52a6c5de4f 184 Pfam PF13302 Acetyltransferase (GNAT) domain 12 149 3.7E-18 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SMALA_RS30955 177780a6790fd82916b2fd52a6c5de4f 184 SUPERFAMILY SSF55729 8 173 6.62E-35 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS05070 941aacc015a6b6b0c02bfd523c4f174d 324 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 17 310 7.3E-73 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMALA_RS05070 941aacc015a6b6b0c02bfd523c4f174d 324 Gene3D G3DSA:3.40.50.1100 105 322 1.0E-41 T 29-03-2018 SMALA_RS05070 941aacc015a6b6b0c02bfd523c4f174d 324 SUPERFAMILY SSF53686 7 318 4.32E-86 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMALA_RS05070 941aacc015a6b6b0c02bfd523c4f174d 324 Gene3D G3DSA:3.40.50.1100 3 104 2.0E-23 T 29-03-2018 SMALA_RS32800 d32032ed2d1946b4355450065048d753 189 SUPERFAMILY SSF160904 2 183 6.8E-48 T 29-03-2018 SMALA_RS32800 d32032ed2d1946b4355450065048d753 189 Pfam PF11706 CGNR zinc finger 141 184 4.0E-18 T 29-03-2018 IPR021005 Zinc finger, CGNR SMALA_RS32800 d32032ed2d1946b4355450065048d753 189 Pfam PF07336 Putative stress-induced transcription regulator 12 136 1.3E-15 T 29-03-2018 IPR010852 Putative stress-induced transcription regulator SMALA_RS32800 d32032ed2d1946b4355450065048d753 189 Gene3D G3DSA:1.10.3300.10 1 186 2.8E-44 T 29-03-2018 IPR023286 ABATE domain SMALA_RS40885 4438b1406fd11de899225596cd3ae9cb 489 SUPERFAMILY SSF53474 150 290 2.2E-12 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS40885 4438b1406fd11de899225596cd3ae9cb 489 SUPERFAMILY SSF53474 367 441 2.2E-12 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS40885 4438b1406fd11de899225596cd3ae9cb 489 Pfam PF10605 3HB-oligomer hydrolase (3HBOH) 366 474 2.2E-9 T 29-03-2018 IPR016582 D-(-)-3-hydroxybutyrate oligomer hydrolase, putative GO:0005615|GO:0019605|GO:0047989 KEGG: 00650+3.1.1.22 SMALA_RS40885 4438b1406fd11de899225596cd3ae9cb 489 Gene3D G3DSA:3.40.50.1820 107 465 4.2E-13 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS40885 4438b1406fd11de899225596cd3ae9cb 489 Pfam PF07519 Tannase and feruloyl esterase 129 258 2.1E-9 T 29-03-2018 IPR011118 Tannase/feruloyl esterase MetaCyc: PWY-6784 SMALA_RS39965 eb939e8698f8ddb2ad58d7b19874822f 331 Gene3D G3DSA:2.60.120.10 56 155 1.3E-6 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SMALA_RS39965 eb939e8698f8ddb2ad58d7b19874822f 331 SUPERFAMILY SSF51182 81 150 1.25E-10 T 29-03-2018 IPR011051 RmlC-like cupin domain SMALA_RS39965 eb939e8698f8ddb2ad58d7b19874822f 331 SUPERFAMILY SSF51182 184 286 1.25E-10 T 29-03-2018 IPR011051 RmlC-like cupin domain SMALA_RS39965 eb939e8698f8ddb2ad58d7b19874822f 331 Gene3D G3DSA:2.60.120.10 197 328 9.4E-7 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SMALA_RS11610 d0be5ec3828e1be4f217321be7ffd413 65 PRINTS PR00352 3Fe-4S ferredoxin signature 48 60 4.7E-6 T 29-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 SMALA_RS11610 d0be5ec3828e1be4f217321be7ffd413 65 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 4.7E-6 T 29-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 SMALA_RS11610 d0be5ec3828e1be4f217321be7ffd413 65 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 4.7E-6 T 29-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 SMALA_RS11610 d0be5ec3828e1be4f217321be7ffd413 65 Gene3D G3DSA:3.30.70.20 1 65 2.0E-7 T 29-03-2018 SMALA_RS11610 d0be5ec3828e1be4f217321be7ffd413 65 SUPERFAMILY SSF54862 2 64 5.8E-12 T 29-03-2018 SMALA_RS11610 d0be5ec3828e1be4f217321be7ffd413 65 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 5 62 4.1E-14 T 29-03-2018 SMALA_RS38985 4a2e7394b2413ebc56dd3f2e1b4cb32d 975 Gene3D G3DSA:3.20.20.80 193 514 2.2E-140 T 29-03-2018 SMALA_RS38985 4a2e7394b2413ebc56dd3f2e1b4cb32d 975 Gene3D G3DSA:3.90.1330.10 515 715 1.0E-66 T 29-03-2018 IPR011099 Glycosyl hydrolase family 67, C-terminal GO:0005576|GO:0045493|GO:0046559 SMALA_RS38985 4a2e7394b2413ebc56dd3f2e1b4cb32d 975 Gene3D G3DSA:3.30.379.10 64 188 2.3E-23 T 29-03-2018 SMALA_RS38985 4a2e7394b2413ebc56dd3f2e1b4cb32d 975 SUPERFAMILY SSF55545 47 192 1.62E-33 T 29-03-2018 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMALA_RS38985 4a2e7394b2413ebc56dd3f2e1b4cb32d 975 Pfam PF07477 Glycosyl hydrolase family 67 C-terminus 494 714 3.1E-75 T 29-03-2018 IPR011099 Glycosyl hydrolase family 67, C-terminal GO:0005576|GO:0045493|GO:0046559 SMALA_RS38985 4a2e7394b2413ebc56dd3f2e1b4cb32d 975 SUPERFAMILY SSF51445 195 715 2.84E-213 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS38985 4a2e7394b2413ebc56dd3f2e1b4cb32d 975 Pfam PF03648 Glycosyl hydrolase family 67 N-terminus 52 173 9.0E-23 T 29-03-2018 IPR005154 Alpha glucuronidase, N-terminal GO:0045493|GO:0046559 SMALA_RS38985 4a2e7394b2413ebc56dd3f2e1b4cb32d 975 Pfam PF07488 Glycosyl hydrolase family 67 middle domain 177 493 2.9E-141 T 29-03-2018 IPR011100 Glycosyl hydrolase family 67, catalytic domain GO:0005576|GO:0045493|GO:0046559 SMALA_RS30555 5affbffb2f3a330ccce10c25f5b9bb7a 495 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 18 450 4.4E-95 T 29-03-2018 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 SMALA_RS11085 ab585b1e6e8052afdfc64a2188fbb172 137 Pfam PF13581 Histidine kinase-like ATPase domain 23 118 1.3E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS11085 ab585b1e6e8052afdfc64a2188fbb172 137 SUPERFAMILY SSF55874 40 131 1.64E-7 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS11085 ab585b1e6e8052afdfc64a2188fbb172 137 Gene3D G3DSA:3.30.565.10 11 133 1.4E-12 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS28535 ed195e8956c2958505808456629d293f 160 Gene3D G3DSA:1.10.287.1060 16 121 0.0013 T 29-03-2018 SMALA_RS03250 1048effec92a053dd8ce3db6d62fda60 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 1.7E-20 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMALA_RS03250 1048effec92a053dd8ce3db6d62fda60 302 SUPERFAMILY SSF53850 92 298 7.45E-39 T 29-03-2018 SMALA_RS03250 1048effec92a053dd8ce3db6d62fda60 302 Gene3D G3DSA:1.10.10.10 1 84 1.3E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS03250 1048effec92a053dd8ce3db6d62fda60 302 Pfam PF03466 LysR substrate binding domain 89 295 6.0E-42 T 29-03-2018 IPR005119 LysR, substrate-binding SMALA_RS03250 1048effec92a053dd8ce3db6d62fda60 302 Gene3D G3DSA:3.40.190.10 90 181 2.7E-22 T 29-03-2018 SMALA_RS03250 1048effec92a053dd8ce3db6d62fda60 302 Gene3D G3DSA:3.40.190.10 182 271 5.3E-24 T 29-03-2018 SMALA_RS03250 1048effec92a053dd8ce3db6d62fda60 302 SUPERFAMILY SSF46785 1 112 1.36E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS22940 3eecd7cbd2d10a943c3ce1f9d0916fb7 104 Pfam PF02467 Transcription factor WhiB 17 87 1.0E-24 T 29-03-2018 IPR034768 WhiB-like iron-sulfur binding domain SMALA_RS22940 3eecd7cbd2d10a943c3ce1f9d0916fb7 104 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 95 19.382 T 29-03-2018 IPR003482 Transcription factor WhiB SMALA_RS12490 08e92f21af9ad3cd7130a91dc71287f9 305 SUPERFAMILY SSF161098 43 300 3.05E-56 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS12490 08e92f21af9ad3cd7130a91dc71287f9 305 Gene3D G3DSA:1.10.3720.10 37 293 3.7E-36 T 29-03-2018 SMALA_RS12490 08e92f21af9ad3cd7130a91dc71287f9 305 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 118 291 5.9E-15 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS20455 ff056eeb71eb20ab80fc0641473714c3 184 SUPERFAMILY SSF55811 24 176 5.15E-17 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMALA_RS20455 ff056eeb71eb20ab80fc0641473714c3 184 Pfam PF00293 NUDIX domain 51 169 5.6E-12 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SMALA_RS20455 ff056eeb71eb20ab80fc0641473714c3 184 Gene3D G3DSA:3.90.79.10 47 179 2.3E-18 T 29-03-2018 SMALA_RS04815 1ff2c6134c2e14e43f34649d7cf44cb0 401 Gene3D G3DSA:1.20.1250.20 3 190 4.0E-28 T 29-03-2018 SMALA_RS04815 1ff2c6134c2e14e43f34649d7cf44cb0 401 SUPERFAMILY SSF103473 3 382 9.42E-58 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS04815 1ff2c6134c2e14e43f34649d7cf44cb0 401 Pfam PF07690 Major Facilitator Superfamily 8 321 1.0E-39 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS04815 1ff2c6134c2e14e43f34649d7cf44cb0 401 Gene3D G3DSA:1.20.1250.20 191 391 1.6E-19 T 29-03-2018 SMALA_RS17390 9b84fce00d6e3b77579f8a8b80cb48eb 361 Gene3D G3DSA:1.10.3470.10 22 357 3.3E-58 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SMALA_RS17390 9b84fce00d6e3b77579f8a8b80cb48eb 361 SUPERFAMILY SSF81345 22 348 2.48E-64 T 29-03-2018 IPR029022 ABC transporter, BtuC-like SMALA_RS17390 9b84fce00d6e3b77579f8a8b80cb48eb 361 Pfam PF01032 FecCD transport family 39 348 9.3E-75 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 SMALA_RS05120 76c02edad88a88b4d41dcc785103eb70 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 57 5.0E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS05120 76c02edad88a88b4d41dcc785103eb70 207 Gene3D G3DSA:1.10.357.10 56 199 1.2E-14 T 29-03-2018 SMALA_RS05120 76c02edad88a88b4d41dcc785103eb70 207 Gene3D G3DSA:1.10.10.60 1 55 1.0E-14 T 29-03-2018 SMALA_RS05120 76c02edad88a88b4d41dcc785103eb70 207 SUPERFAMILY SSF46689 3 75 4.57E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS05120 76c02edad88a88b4d41dcc785103eb70 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 9.2E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS05120 76c02edad88a88b4d41dcc785103eb70 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 9.2E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS37180 3647d04a63835193779cb302b13376cf 78 Pfam PF04149 Domain of unknown function (DUF397) 17 69 8.8E-15 T 29-03-2018 IPR007278 Domain of unknown function DUF397 SMALA_RS01115 b6d45349e273a2ddf3897840708b13c9 246 SUPERFAMILY SSF54427 99 241 4.99E-23 T 29-03-2018 IPR032710 NTF2-like domain SMALA_RS01115 b6d45349e273a2ddf3897840708b13c9 246 Gene3D G3DSA:3.10.450.50 92 245 1.4E-23 T 29-03-2018 SMALA_RS01115 b6d45349e273a2ddf3897840708b13c9 246 Pfam PF13577 SnoaL-like domain 99 218 1.9E-12 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain SMALA_RS27445 d59ec8bc54a8751ea7c4aac7783ba813 255 SUPERFAMILY SSF52096 3 253 4.25E-83 T 29-03-2018 IPR029045 ClpP/crotonase-like domain SMALA_RS27445 d59ec8bc54a8751ea7c4aac7783ba813 255 Pfam PF00378 Enoyl-CoA hydratase/isomerase 8 248 3.2E-68 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 SMALA_RS27445 d59ec8bc54a8751ea7c4aac7783ba813 255 Gene3D G3DSA:3.90.226.10 2 213 3.0E-75 T 29-03-2018 SMALA_RS27445 d59ec8bc54a8751ea7c4aac7783ba813 255 Gene3D G3DSA:1.10.12.10 214 249 1.5E-13 T 29-03-2018 IPR014748 Crontonase, C-terminal SMALA_RS27445 d59ec8bc54a8751ea7c4aac7783ba813 255 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 96 116 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 SMALA_RS32810 3d3fb514b96abf66431e63ab7c3e06a8 150 TIGRFAM TIGR02611 TIGR02611: TIGR02611 family protein 30 144 1.4E-36 T 29-03-2018 IPR013434 Conserved hypothetical protein CHP02611 SMALA_RS32810 3d3fb514b96abf66431e63ab7c3e06a8 150 Pfam PF09656 Putative transmembrane protein (PGPGW) 49 101 1.1E-20 T 29-03-2018 IPR019099 Uncharacterised protein family PGPGW, transmembrane SMALA_RS34275 b7cfae388cd5c6d9679596049e3fffab 210 SUPERFAMILY SSF55874 112 203 5.62E-7 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS34275 b7cfae388cd5c6d9679596049e3fffab 210 Gene3D G3DSA:3.30.565.10 75 209 6.9E-14 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS34275 b7cfae388cd5c6d9679596049e3fffab 210 Pfam PF13581 Histidine kinase-like ATPase domain 86 182 3.2E-10 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS17530 31dce1b2873406593b0f24fa0e83528f 287 Gene3D G3DSA:3.40.50.1000 31 285 1.1E-22 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS17530 31dce1b2873406593b0f24fa0e83528f 287 TIGRFAM TIGR00685 T6PP: trehalose-phosphatase 31 279 3.6E-33 T 29-03-2018 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 SMALA_RS17530 31dce1b2873406593b0f24fa0e83528f 287 Pfam PF02358 Trehalose-phosphatase 36 250 1.0E-26 T 29-03-2018 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 SMALA_RS17530 31dce1b2873406593b0f24fa0e83528f 287 SUPERFAMILY SSF56784 34 279 9.41E-33 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS00570 d434feb3f953a0dc24682ba9d800cba0 275 Pfam PF04231 Endonuclease I 60 268 3.5E-39 T 29-03-2018 IPR007346 Endonuclease I GO:0004518 SMALA_RS00570 d434feb3f953a0dc24682ba9d800cba0 275 SUPERFAMILY SSF54060 56 268 5.3E-57 T 29-03-2018 SMALA_RS28610 6d40c8860a9b10fa348bb1bf470f76e1 612 Pfam PF13360 PQQ-like domain 250 518 2.1E-6 T 29-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat SMALA_RS28610 6d40c8860a9b10fa348bb1bf470f76e1 612 SUPERFAMILY SSF50998 266 593 5.89E-8 T 29-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily SMALA_RS28610 6d40c8860a9b10fa348bb1bf470f76e1 612 Gene3D G3DSA:2.130.10.10 162 597 1.9E-4 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMALA_RS32670 7ec692d01fb1b0371bc2ca48f546c458 418 Pfam PF03237 Terminase-like family 29 225 1.4E-12 T 29-03-2018 SMALA_RS32670 7ec692d01fb1b0371bc2ca48f546c458 418 TIGRFAM TIGR01547 phage_term_2: phage terminase, large subunit, PBSX family 28 400 1.1E-34 T 29-03-2018 IPR006437 Bacteriophage terminase, large subunit GO:0006323 SMALA_RS15945 8899c037ea1716790561f668a777ed7c 410 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 164 317 2.0E-46 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain SMALA_RS15945 8899c037ea1716790561f668a777ed7c 410 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 164 317 1.2E-40 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain SMALA_RS30515 bf1f82d24aae596c44b7b969ac6f51fd 123 Pfam PF13309 HTH domain 56 117 1.7E-20 T 29-03-2018 SMALA_RS30515 bf1f82d24aae596c44b7b969ac6f51fd 123 Gene3D G3DSA:1.10.10.60 41 120 2.3E-5 T 29-03-2018 SMALA_RS26710 c694612560fdd405d228ab4d900c0bbe 105 Gene3D G3DSA:3.40.50.620 5 105 5.4E-9 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS31140 f9bfcfbd0770418c67d28263ff218bdf 389 Pfam PF01494 FAD binding domain 7 357 2.2E-17 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 SMALA_RS31140 f9bfcfbd0770418c67d28263ff218bdf 389 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 1.3E-18 T 29-03-2018 SMALA_RS31140 f9bfcfbd0770418c67d28263ff218bdf 389 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 311 327 1.3E-18 T 29-03-2018 SMALA_RS31140 f9bfcfbd0770418c67d28263ff218bdf 389 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 296 311 1.3E-18 T 29-03-2018 SMALA_RS31140 f9bfcfbd0770418c67d28263ff218bdf 389 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 154 169 1.3E-18 T 29-03-2018 SMALA_RS31140 f9bfcfbd0770418c67d28263ff218bdf 389 Gene3D G3DSA:3.50.50.60 1 378 2.2E-39 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS31140 f9bfcfbd0770418c67d28263ff218bdf 389 SUPERFAMILY SSF51905 281 373 2.51E-48 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS31140 f9bfcfbd0770418c67d28263ff218bdf 389 SUPERFAMILY SSF51905 6 175 2.51E-48 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS16725 3a69c111ff2746561fe236fa0628b582 377 SUPERFAMILY SSF51905 3 168 2.25E-45 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS16725 3a69c111ff2746561fe236fa0628b582 377 SUPERFAMILY SSF51905 272 364 2.25E-45 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS16725 3a69c111ff2746561fe236fa0628b582 377 Pfam PF01494 FAD binding domain 117 324 1.2E-9 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 SMALA_RS16725 3a69c111ff2746561fe236fa0628b582 377 Pfam PF01494 FAD binding domain 3 47 3.2E-5 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 SMALA_RS16725 3a69c111ff2746561fe236fa0628b582 377 Gene3D G3DSA:3.50.50.60 1 377 1.3E-38 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS16725 3a69c111ff2746561fe236fa0628b582 377 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 1.4E-12 T 29-03-2018 SMALA_RS16725 3a69c111ff2746561fe236fa0628b582 377 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 147 162 1.4E-12 T 29-03-2018 SMALA_RS16725 3a69c111ff2746561fe236fa0628b582 377 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 287 302 1.4E-12 T 29-03-2018 SMALA_RS05720 5ebb577b7e61406e8411f6537b631e57 150 Pfam PF13564 DoxX-like family 36 127 2.4E-15 T 29-03-2018 IPR032808 DoxX family SMALA_RS12255 5153aeab224626c5ceada5aec6b0c961 329 Pfam PF00294 pfkB family carbohydrate kinase 41 301 2.0E-37 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB SMALA_RS12255 5153aeab224626c5ceada5aec6b0c961 329 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 254 267 - T 29-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 SMALA_RS12255 5153aeab224626c5ceada5aec6b0c961 329 SUPERFAMILY SSF53613 16 310 2.81E-50 T 29-03-2018 IPR029056 Ribokinase-like SMALA_RS12255 5153aeab224626c5ceada5aec6b0c961 329 Gene3D G3DSA:3.40.1190.20 15 315 3.0E-52 T 29-03-2018 IPR029056 Ribokinase-like SMALA_RS39365 8deba66846d37e80f09dad28df28b487 330 Gene3D G3DSA:3.40.190.10 85 214 8.6E-23 T 29-03-2018 SMALA_RS39365 8deba66846d37e80f09dad28df28b487 330 SUPERFAMILY SSF53850 166 315 1.37E-32 T 29-03-2018 SMALA_RS39365 8deba66846d37e80f09dad28df28b487 330 SUPERFAMILY SSF53850 11 136 1.37E-32 T 29-03-2018 SMALA_RS05035 92d56e29729359b7794469ad232eee24 297 SUPERFAMILY SSF161098 94 280 3.66E-31 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS05035 92d56e29729359b7794469ad232eee24 297 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 119 287 7.7E-26 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS05035 92d56e29729359b7794469ad232eee24 297 Gene3D G3DSA:1.10.3720.10 30 294 4.0E-25 T 29-03-2018 SMALA_RS15405 8aacfd7294709396929df44ef8f0c133 465 SUPERFAMILY SSF103473 18 441 6.67E-39 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS15405 8aacfd7294709396929df44ef8f0c133 465 Gene3D G3DSA:1.20.1250.20 23 221 1.8E-14 T 29-03-2018 SMALA_RS15405 8aacfd7294709396929df44ef8f0c133 465 Pfam PF07690 Major Facilitator Superfamily 49 397 1.2E-19 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS15405 8aacfd7294709396929df44ef8f0c133 465 Gene3D G3DSA:1.20.1250.20 230 442 6.4E-18 T 29-03-2018 SMALA_RS32065 714707d957e8a9366dc290a84e1259c7 290 Pfam PF00535 Glycosyl transferase family 2 6 128 1.2E-8 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 SMALA_RS32065 714707d957e8a9366dc290a84e1259c7 290 Gene3D G3DSA:3.90.550.10 5 229 1.1E-28 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS32065 714707d957e8a9366dc290a84e1259c7 290 SUPERFAMILY SSF53448 5 219 4.88E-36 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS31795 df8c71db7836fbeffe84861a1378706e 300 SUPERFAMILY SSF46689 14 86 1.24E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS31795 df8c71db7836fbeffe84861a1378706e 300 Pfam PF01418 Helix-turn-helix domain, rpiR family 13 85 9.6E-9 T 29-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 SMALA_RS31795 df8c71db7836fbeffe84861a1378706e 300 Gene3D G3DSA:3.40.50.10490 107 289 2.8E-24 T 29-03-2018 SMALA_RS31795 df8c71db7836fbeffe84861a1378706e 300 Gene3D G3DSA:1.10.10.10 7 88 1.4E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS31795 df8c71db7836fbeffe84861a1378706e 300 SUPERFAMILY SSF53697 106 268 1.56E-22 T 29-03-2018 SMALA_RS31795 df8c71db7836fbeffe84861a1378706e 300 Pfam PF01380 SIS domain 140 264 5.4E-12 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 SMALA_RS14540 8bcaa91cbab304be27616559ced90515 417 Gene3D G3DSA:3.30.565.10 264 393 1.2E-11 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS14540 8bcaa91cbab304be27616559ced90515 417 SUPERFAMILY SSF55874 276 377 3.01E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS14540 8bcaa91cbab304be27616559ced90515 417 Pfam PF07730 Histidine kinase 199 264 9.4E-15 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMALA_RS20175 564f192f03854f9a77713742050062cd 690 Pfam PF05787 Bacterial protein of unknown function (DUF839) 101 651 1.4E-172 T 29-03-2018 IPR008557 Protein of unknown function DUF839 SMALA_RS20175 564f192f03854f9a77713742050062cd 690 Gene3D G3DSA:2.120.10.30 254 666 0.0056 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like SMALA_RS34040 202cbcae57e10b657bc0738089c12b7e 242 SUPERFAMILY SSF48498 94 227 4.0E-22 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS34040 202cbcae57e10b657bc0738089c12b7e 242 SUPERFAMILY SSF46689 14 80 1.69E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS34040 202cbcae57e10b657bc0738089c12b7e 242 Gene3D G3DSA:1.10.357.10 62 233 1.5E-29 T 29-03-2018 SMALA_RS34040 202cbcae57e10b657bc0738089c12b7e 242 Gene3D G3DSA:1.10.10.60 4 61 7.4E-6 T 29-03-2018 SMALA_RS22355 e376799dfbd08a88dbd24f0f463de63f 406 Gene3D G3DSA:3.20.20.140 8 403 3.2E-69 T 29-03-2018 SMALA_RS22355 e376799dfbd08a88dbd24f0f463de63f 406 Pfam PF04909 Amidohydrolase 101 399 2.7E-44 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 SMALA_RS22355 e376799dfbd08a88dbd24f0f463de63f 406 SUPERFAMILY SSF51556 14 42 1.61E-76 T 29-03-2018 IPR032466 Metal-dependent hydrolase SMALA_RS22355 e376799dfbd08a88dbd24f0f463de63f 406 SUPERFAMILY SSF51556 92 403 1.61E-76 T 29-03-2018 IPR032466 Metal-dependent hydrolase SMALA_RS37135 b899fe685e63f8a54597761c5197cdc5 260 Pfam PF13699 Domain of unknown function (DUF4157) 93 170 2.7E-32 T 29-03-2018 IPR025295 Domain of unknown function DUF4157 SMALA_RS12860 f9b6407b1d1c2d9342d984ffeaba3d58 436 SUPERFAMILY SSF55874 298 412 3.61E-11 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS12860 f9b6407b1d1c2d9342d984ffeaba3d58 436 Gene3D G3DSA:3.30.565.10 286 414 4.2E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS12860 f9b6407b1d1c2d9342d984ffeaba3d58 436 Pfam PF07730 Histidine kinase 196 266 4.8E-15 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMALA_RS28540 f62865b4722e30f682048692ec859127 499 Gene3D G3DSA:1.10.287.1060 33 118 3.3E-7 T 29-03-2018 SMALA_RS28540 f62865b4722e30f682048692ec859127 499 SUPERFAMILY SSF140453 37 113 2.75E-5 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like SMALA_RS41550 a5e1d25fbc4c7948bb0bf9b9721a9cc4 307 Gene3D G3DSA:3.40.50.720 1 299 1.6E-62 T 29-03-2018 SMALA_RS41550 a5e1d25fbc4c7948bb0bf9b9721a9cc4 307 SUPERFAMILY SSF51735 11 295 1.45E-55 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS41550 a5e1d25fbc4c7948bb0bf9b9721a9cc4 307 Pfam PF00106 short chain dehydrogenase 17 214 5.1E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS41550 a5e1d25fbc4c7948bb0bf9b9721a9cc4 307 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 2.9E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS41550 a5e1d25fbc4c7948bb0bf9b9721a9cc4 307 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 88 99 2.9E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS41550 a5e1d25fbc4c7948bb0bf9b9721a9cc4 307 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 172 191 2.9E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS41550 a5e1d25fbc4c7948bb0bf9b9721a9cc4 307 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 6.4E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS41550 a5e1d25fbc4c7948bb0bf9b9721a9cc4 307 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 17 34 6.4E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS41550 a5e1d25fbc4c7948bb0bf9b9721a9cc4 307 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 6.4E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS41550 a5e1d25fbc4c7948bb0bf9b9721a9cc4 307 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 191 6.4E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS42720 4b039d3a011a95854a4e60f36aec422b 418 SUPERFAMILY SSF48256 85 408 1.44E-54 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 SMALA_RS42720 4b039d3a011a95854a4e60f36aec422b 418 Gene3D G3DSA:1.10.230.10 299 383 3.5E-13 T 29-03-2018 IPR016143 Citrate synthase-like, small alpha subdomain SMALA_RS42720 4b039d3a011a95854a4e60f36aec422b 418 Pfam PF12728 Helix-turn-helix domain 11 58 1.7E-6 T 29-03-2018 SMALA_RS42720 4b039d3a011a95854a4e60f36aec422b 418 Pfam PF00285 Citrate synthase, C-terminal domain 87 406 4.3E-53 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 SMALA_RS42720 4b039d3a011a95854a4e60f36aec422b 418 Gene3D G3DSA:1.10.10.10 11 61 2.7E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS42720 4b039d3a011a95854a4e60f36aec422b 418 PRINTS PR00143 Citrate synthase signature 234 249 8.2E-8 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 SMALA_RS42720 4b039d3a011a95854a4e60f36aec422b 418 PRINTS PR00143 Citrate synthase signature 256 284 8.2E-8 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 SMALA_RS42720 4b039d3a011a95854a4e60f36aec422b 418 PRINTS PR00143 Citrate synthase signature 384 398 8.2E-8 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 SMALA_RS42720 4b039d3a011a95854a4e60f36aec422b 418 PRINTS PR00143 Citrate synthase signature 310 330 8.2E-8 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 SMALA_RS42720 4b039d3a011a95854a4e60f36aec422b 418 SUPERFAMILY SSF46955 11 59 3.02E-5 T 29-03-2018 IPR009061 Putative DNA-binding domain SMALA_RS42720 4b039d3a011a95854a4e60f36aec422b 418 Gene3D G3DSA:1.10.580.10 62 298 9.5E-34 T 29-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain SMALA_RS22535 5035c16db462436d125ebf155b167268 214 ProSitePatterns PS00474 Ribosomal protein L3 signature. 105 128 - T 29-03-2018 IPR019926 Ribosomal protein L3, conserved site SMALA_RS22535 5035c16db462436d125ebf155b167268 214 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 7 208 3.7E-89 T 29-03-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS22535 5035c16db462436d125ebf155b167268 214 SUPERFAMILY SSF50447 5 212 8.83E-80 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain SMALA_RS22535 5035c16db462436d125ebf155b167268 214 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 5 211 39.934 T 29-03-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS22535 5035c16db462436d125ebf155b167268 214 Pfam PF00297 Ribosomal protein L3 99 186 2.9E-14 T 29-03-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMALA_RS22535 5035c16db462436d125ebf155b167268 214 Gene3D G3DSA:4.10.960.10 61 169 4.2E-35 T 29-03-2018 SMALA_RS32720 eca74539efdb70649eda09c07c56e744 143 Gene3D G3DSA:1.10.10.10 35 136 4.7E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS32720 eca74539efdb70649eda09c07c56e744 143 Pfam PF01638 HxlR-like helix-turn-helix 38 125 6.3E-27 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type SMALA_RS32720 eca74539efdb70649eda09c07c56e744 143 SUPERFAMILY SSF46785 27 134 1.46E-32 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS34705 693fac60da86b3d9450202b630891373 141 Gene3D G3DSA:3.40.630.30 76 137 1.2E-11 T 29-03-2018 SMALA_RS34705 693fac60da86b3d9450202b630891373 141 Pfam PF00583 Acetyltransferase (GNAT) family 31 126 4.1E-14 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SMALA_RS34705 693fac60da86b3d9450202b630891373 141 Gene3D G3DSA:3.40.630.30 1 75 1.7E-16 T 29-03-2018 SMALA_RS34705 693fac60da86b3d9450202b630891373 141 SUPERFAMILY SSF55729 2 133 3.88E-27 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS37655 922e1355cf69bbaf1c9d00764f01f5d0 263 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 1 254 2.2E-34 T 29-03-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase SMALA_RS40760 d152e3d69d95ccb89120e89ada4efd03 284 SUPERFAMILY SSF52821 148 268 1.22E-22 T 29-03-2018 IPR001763 Rhodanese-like domain SMALA_RS40760 d152e3d69d95ccb89120e89ada4efd03 284 SMART SM00450 1 128 1.7E-26 T 29-03-2018 IPR001763 Rhodanese-like domain SMALA_RS40760 d152e3d69d95ccb89120e89ada4efd03 284 SMART SM00450 149 265 7.8E-13 T 29-03-2018 IPR001763 Rhodanese-like domain SMALA_RS40760 d152e3d69d95ccb89120e89ada4efd03 284 SUPERFAMILY SSF52821 2 144 1.96E-36 T 29-03-2018 IPR001763 Rhodanese-like domain SMALA_RS40760 d152e3d69d95ccb89120e89ada4efd03 284 Gene3D G3DSA:3.40.250.10 146 279 5.6E-20 T 29-03-2018 IPR001763 Rhodanese-like domain SMALA_RS40760 d152e3d69d95ccb89120e89ada4efd03 284 ProSitePatterns PS00380 Rhodanese signature 1. 35 46 - T 29-03-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 SMALA_RS40760 d152e3d69d95ccb89120e89ada4efd03 284 Pfam PF00581 Rhodanese-like domain 160 261 4.0E-9 T 29-03-2018 IPR001763 Rhodanese-like domain SMALA_RS40760 d152e3d69d95ccb89120e89ada4efd03 284 Pfam PF00581 Rhodanese-like domain 5 124 2.3E-19 T 29-03-2018 IPR001763 Rhodanese-like domain SMALA_RS40760 d152e3d69d95ccb89120e89ada4efd03 284 ProSitePatterns PS00380 Rhodanese signature 1. 174 185 - T 29-03-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 SMALA_RS40760 d152e3d69d95ccb89120e89ada4efd03 284 Gene3D G3DSA:3.40.250.10 1 145 1.0E-31 T 29-03-2018 IPR001763 Rhodanese-like domain SMALA_RS40660 81940130202d39e037e31ae40452223c 120 Pfam PF04343 Protein of unknown function, DUF488 7 116 2.2E-31 T 29-03-2018 IPR007438 Protein of unknown function DUF488 SMALA_RS24845 0625f66f01e30cd9f622947818eaf230 233 SUPERFAMILY SSF159234 41 210 2.62E-44 T 29-03-2018 IPR007295 Domain of unknown function DUF402 SMALA_RS24845 0625f66f01e30cd9f622947818eaf230 233 Pfam PF04167 Protein of unknown function (DUF402) 98 162 1.4E-13 T 29-03-2018 IPR007295 Domain of unknown function DUF402 SMALA_RS24845 0625f66f01e30cd9f622947818eaf230 233 Gene3D G3DSA:2.40.380.10 15 209 4.8E-80 T 29-03-2018 IPR007295 Domain of unknown function DUF402 SMALA_RS34895 8c161ef37d25769da1b5a81d76ddeb9f 272 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 212 229 - T 29-03-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199 SMALA_RS34895 8c161ef37d25769da1b5a81d76ddeb9f 272 SUPERFAMILY SSF64005 39 262 1.31E-70 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 SMALA_RS34895 8c161ef37d25769da1b5a81d76ddeb9f 272 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 40 267 35.307 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 SMALA_RS34895 8c161ef37d25769da1b5a81d76ddeb9f 272 Gene3D G3DSA:3.40.1180.10 33 269 1.4E-75 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 SMALA_RS34895 8c161ef37d25769da1b5a81d76ddeb9f 272 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 41 266 1.0E-70 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 SMALA_RS34895 8c161ef37d25769da1b5a81d76ddeb9f 272 Pfam PF01255 Putative undecaprenyl diphosphate synthase 47 266 7.1E-68 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 SMALA_RS08000 852a57b3e6f6c1bffee72914a86d86e1 249 Pfam PF02633 Creatinine amidohydrolase 20 239 1.8E-57 T 29-03-2018 IPR003785 Creatininase/formamide hydrolase KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167 SMALA_RS08000 852a57b3e6f6c1bffee72914a86d86e1 249 Gene3D G3DSA:3.40.50.10310 6 246 4.3E-67 T 29-03-2018 IPR024087 Creatininase-like domain KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167 SMALA_RS08000 852a57b3e6f6c1bffee72914a86d86e1 249 SUPERFAMILY SSF102215 17 240 3.79E-58 T 29-03-2018 IPR024087 Creatininase-like domain KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167 SMALA_RS20375 b9b8a071a1e0cfefa76086d91f4b8285 162 SUPERFAMILY SSF102405 1 158 1.01E-15 T 29-03-2018 SMALA_RS20375 b9b8a071a1e0cfefa76086d91f4b8285 162 Gene3D G3DSA:3.40.50.450 1 162 9.9E-38 T 29-03-2018 SMALA_RS34305 b993a0cdb0963cbd5500c0f846bbb5fe 332 Gene3D G3DSA:3.40.190.10 270 329 0.12 T 29-03-2018 SMALA_RS34305 b993a0cdb0963cbd5500c0f846bbb5fe 332 Gene3D G3DSA:3.40.190.10 130 257 2.6E-15 T 29-03-2018 SMALA_RS34305 b993a0cdb0963cbd5500c0f846bbb5fe 332 SUPERFAMILY SSF53850 119 303 1.01E-12 T 29-03-2018 SMALA_RS34305 b993a0cdb0963cbd5500c0f846bbb5fe 332 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 72 274 4.3E-25 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 SMALA_RS34305 b993a0cdb0963cbd5500c0f846bbb5fe 332 PIRSF PIRSF017082 3 332 8.5E-82 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 SMALA_RS13600 1f999da7da7d153db0c4ada367d7aad3 72 Pfam PF03621 MbtH-like protein 1 53 1.7E-29 T 29-03-2018 IPR005153 MbtH-like protein SMALA_RS13600 1f999da7da7d153db0c4ada367d7aad3 72 SUPERFAMILY SSF160582 1 69 1.1E-32 T 29-03-2018 SMALA_RS13600 1f999da7da7d153db0c4ada367d7aad3 72 SMART SM00923 3 53 6.1E-34 T 29-03-2018 IPR005153 MbtH-like protein SMALA_RS13600 1f999da7da7d153db0c4ada367d7aad3 72 Gene3D G3DSA:3.90.820.10 2 68 1.2E-36 T 29-03-2018 SMALA_RS07140 b50917ed914b310e1b6cbb334ee5bf3a 219 SUPERFAMILY SSF46689 16 86 2.31E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS07140 b50917ed914b310e1b6cbb334ee5bf3a 219 Gene3D G3DSA:1.10.357.10 73 215 4.2E-23 T 29-03-2018 SMALA_RS07140 b50917ed914b310e1b6cbb334ee5bf3a 219 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 49 72 8.8E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS07140 b50917ed914b310e1b6cbb334ee5bf3a 219 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 41 8.8E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS07140 b50917ed914b310e1b6cbb334ee5bf3a 219 Pfam PF00440 Bacterial regulatory proteins, tetR family 30 72 4.4E-13 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS07140 b50917ed914b310e1b6cbb334ee5bf3a 219 Gene3D G3DSA:1.10.10.60 1 72 4.2E-16 T 29-03-2018 SMALA_RS37170 a347cd01e30ba3f262bbb8311fed3147 136 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 13 133 8.8E-26 T 29-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 SMALA_RS37170 a347cd01e30ba3f262bbb8311fed3147 136 SUPERFAMILY SSF55961 1 135 1.65E-34 T 29-03-2018 SMALA_RS37170 a347cd01e30ba3f262bbb8311fed3147 136 Gene3D G3DSA:3.30.530.20 1 136 1.5E-27 T 29-03-2018 IPR023393 START-like domain SMALA_RS36470 8ec32a2f5d22c1331ea33635c1cbd028 245 Pfam PF06912 Protein of unknown function (DUF1275) 32 227 8.2E-31 T 29-03-2018 IPR010699 Protein of unknown function DUF1275 SMALA_RS07215 5fd468a2329f541bb12d85ffbf23ca8e 321 Pfam PF13280 WYL domain 152 318 1.8E-30 T 29-03-2018 IPR026881 WYL domain SMALA_RS25915 90b3f8924315af28f1627796902ef642 270 Gene3D G3DSA:1.20.1260.10 54 270 2.5E-46 T 29-03-2018 IPR012347 Ferritin-related SMALA_RS25915 90b3f8924315af28f1627796902ef642 270 SUPERFAMILY SSF47240 60 181 9.06E-9 T 29-03-2018 IPR009078 Ferritin-like superfamily SMALA_RS25915 90b3f8924315af28f1627796902ef642 270 Pfam PF13794 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like 54 238 3.1E-95 T 29-03-2018 SMALA_RS17810 70144fd5a9cfa59d232bd6e9f75744c9 173 Pfam PF10722 Putative bacterial sensory transduction regulator 15 136 1.1E-21 T 29-03-2018 IPR019660 Putative sensory transduction regulator YbjN SMALA_RS17810 70144fd5a9cfa59d232bd6e9f75744c9 173 Gene3D G3DSA:3.30.1460.10 12 147 2.6E-42 T 29-03-2018 SMALA_RS17810 70144fd5a9cfa59d232bd6e9f75744c9 173 SUPERFAMILY SSF69635 12 139 3.1E-35 T 29-03-2018 SMALA_RS12015 dae87eb2fb39b650aa4192705115d8e9 222 SUPERFAMILY SSF51182 5 215 4.69E-52 T 29-03-2018 IPR011051 RmlC-like cupin domain SMALA_RS12015 dae87eb2fb39b650aa4192705115d8e9 222 Gene3D G3DSA:2.60.120.10 129 217 1.4E-16 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SMALA_RS12015 dae87eb2fb39b650aa4192705115d8e9 222 Pfam PF02678 Pirin 16 118 2.6E-31 T 29-03-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 SMALA_RS12015 dae87eb2fb39b650aa4192705115d8e9 222 Gene3D G3DSA:2.60.120.10 13 128 5.6E-38 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SMALA_RS42655 83d3b518186163a0230b53911942a403 253 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 106 222 1.3E-21 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMALA_RS42655 83d3b518186163a0230b53911942a403 253 Gene3D G3DSA:3.10.180.10 1 97 2.7E-8 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS42655 83d3b518186163a0230b53911942a403 253 Gene3D G3DSA:3.10.180.10 98 248 9.1E-27 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS42655 83d3b518186163a0230b53911942a403 253 SUPERFAMILY SSF54593 105 247 4.54E-32 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS42655 83d3b518186163a0230b53911942a403 253 SUPERFAMILY SSF54593 1 88 5.64E-16 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS10250 859a48a9a1744df279a12f0851cf42e6 207 Pfam PF04977 Septum formation initiator 52 101 1.7E-8 T 29-03-2018 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 SMALA_RS42965 e3621a68ab48964f373d2f430c801ac4 736 Pfam PF07510 Protein of unknown function (DUF1524) 450 548 3.9E-7 T 29-03-2018 IPR011089 Domain of unknown function DUF1524 SMALA_RS42965 e3621a68ab48964f373d2f430c801ac4 736 Pfam PF03235 Protein of unknown function DUF262 13 231 6.7E-28 T 29-03-2018 IPR004919 Domain of unknown function DUF262 SMALA_RS37195 735ca27602d3dab8f7aa64cf4c519a69 661 Gene3D G3DSA:3.90.1150.10 292 377 2.1E-15 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS37195 735ca27602d3dab8f7aa64cf4c519a69 661 Pfam PF00155 Aminotransferase class I and II 68 369 8.1E-25 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMALA_RS37195 735ca27602d3dab8f7aa64cf4c519a69 661 SUPERFAMILY SSF53383 34 375 2.58E-53 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS37195 735ca27602d3dab8f7aa64cf4c519a69 661 Gene3D G3DSA:3.40.640.10 55 291 8.7E-24 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS23620 854781ab5d043c5e0f9e1123b613f694 92 Pfam PF13828 Domain of unknown function (DUF4190) 21 79 6.5E-10 T 29-03-2018 IPR025241 Domain of unknown function DUF4190 SMALA_RS38255 877a075aa971e369cd8ef81a38c9bd38 74 SUPERFAMILY SSF160582 3 70 3.53E-30 T 29-03-2018 SMALA_RS38255 877a075aa971e369cd8ef81a38c9bd38 74 Pfam PF03621 MbtH-like protein 2 53 5.9E-27 T 29-03-2018 IPR005153 MbtH-like protein SMALA_RS38255 877a075aa971e369cd8ef81a38c9bd38 74 Gene3D G3DSA:3.90.820.10 3 69 3.1E-34 T 29-03-2018 SMALA_RS38255 877a075aa971e369cd8ef81a38c9bd38 74 SMART SM00923 4 54 3.3E-29 T 29-03-2018 IPR005153 MbtH-like protein SMALA_RS15755 1bfd546376328e98ca91ec82c2298ce5 279 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 8 151 1.0E-9 T 29-03-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal SMALA_RS15755 1bfd546376328e98ca91ec82c2298ce5 279 SMART SM00943 8 186 1.2E-37 T 29-03-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal SMALA_RS15755 1bfd546376328e98ca91ec82c2298ce5 279 SUPERFAMILY SSF56747 2 150 3.4E-5 T 29-03-2018 SMALA_RS07415 d7a1a3543ad3340a49ecf508ecba403a 282 TIGRFAM TIGR03843 TIGR03843: conserved hypothetical protein 8 282 7.4E-105 T 29-03-2018 IPR022292 Conserved hypothetical protein CHP03843 SMALA_RS27535 5c256e261fe8bd3e46afb5594567e1e4 260 Pfam PF07179 SseB protein N-terminal domain 24 133 1.4E-12 T 29-03-2018 IPR009839 SseB protein N-terminal domain SMALA_RS27535 5c256e261fe8bd3e46afb5594567e1e4 260 Pfam PF14581 SseB protein C-terminal domain 149 258 3.7E-25 T 29-03-2018 IPR027945 SseB protein, C-terminal SMALA_RS03780 35556b9fb4e182a2e88fde009fae3bd8 307 SUPERFAMILY SSF48576 94 298 2.1E-13 T 29-03-2018 IPR008949 Isoprenoid synthase domain SMALA_RS03780 35556b9fb4e182a2e88fde009fae3bd8 307 Gene3D G3DSA:1.10.600.10 19 278 4.9E-12 T 29-03-2018 IPR008949 Isoprenoid synthase domain SMALA_RS26635 c7ed0d811daff1a952129cd81278b16d 413 Pfam PF00877 NlpC/P60 family 306 397 1.2E-19 T 29-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain SMALA_RS26635 c7ed0d811daff1a952129cd81278b16d 413 Gene3D G3DSA:3.90.1720.10 284 401 8.1E-35 T 29-03-2018 SMALA_RS26635 c7ed0d811daff1a952129cd81278b16d 413 SUPERFAMILY SSF54001 292 405 6.87E-35 T 29-03-2018 SMALA_RS02055 5d7e498832d2589cd9ed04b63ad826b1 286 Pfam PF11790 Glycosyl hydrolase catalytic core 62 280 1.9E-54 T 29-03-2018 IPR024655 Uncharacterised protein family, glycosyl hydrolase catalytic domain SMALA_RS02055 5d7e498832d2589cd9ed04b63ad826b1 286 Gene3D G3DSA:3.20.20.80 103 281 2.4E-16 T 29-03-2018 SMALA_RS02055 5d7e498832d2589cd9ed04b63ad826b1 286 SUPERFAMILY SSF51445 82 272 6.03E-26 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS35345 bddcfa3e9f84970e28965729105fb95c 417 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 138 412 4.3E-64 T 29-03-2018 IPR008257 Renal dipeptidase family GO:0006508|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 SMALA_RS35345 bddcfa3e9f84970e28965729105fb95c 417 SUPERFAMILY SSF51556 60 334 1.31E-61 T 29-03-2018 IPR032466 Metal-dependent hydrolase SMALA_RS35345 bddcfa3e9f84970e28965729105fb95c 417 SUPERFAMILY SSF51556 371 416 1.31E-61 T 29-03-2018 IPR032466 Metal-dependent hydrolase SMALA_RS35345 bddcfa3e9f84970e28965729105fb95c 417 Gene3D G3DSA:3.20.20.140 54 296 1.4E-51 T 29-03-2018 SMALA_RS35345 bddcfa3e9f84970e28965729105fb95c 417 Gene3D G3DSA:3.20.20.140 297 417 6.4E-21 T 29-03-2018 SMALA_RS07930 664a7f9c9d9762220c3c03c111432ff1 29 TIGRFAM TIGR02115 potass_kdpF: K+-transporting ATPase, F subunit 6 29 2.1E-10 T 29-03-2018 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 SMALA_RS07930 664a7f9c9d9762220c3c03c111432ff1 29 Pfam PF09604 F subunit of K+-transporting ATPase (Potass_KdpF) 6 29 8.7E-10 T 29-03-2018 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 SMALA_RS21480 e06167c01fdca7529cf74546a07a8516 85 Pfam PF11298 Protein of unknown function (DUF3099) 3 59 4.5E-6 T 29-03-2018 IPR021449 Protein of unknown function DUF3099 SMALA_RS05840 7251163e84dbfafc759918f694e8d3c7 131 SUPERFAMILY SSF52091 4 84 3.53E-6 T 29-03-2018 IPR002645 STAS domain SMALA_RS37750 03649ec425caccbe19539c9e1d3c9ead 649 Pfam PF04865 Baseplate J-like protein 405 564 7.6E-8 T 29-03-2018 IPR006949 Baseplate protein J-like SMALA_RS30850 558f8d740c7e69f736d9192dba2a8ba1 359 Gene3D G3DSA:1.10.4080.10 3 359 1.8E-59 T 29-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 SMALA_RS30850 558f8d740c7e69f736d9192dba2a8ba1 359 SUPERFAMILY SSF101478 8 350 1.7E-41 T 29-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 SMALA_RS30850 558f8d740c7e69f736d9192dba2a8ba1 359 Pfam PF03747 ADP-ribosylglycohydrolase 14 320 9.6E-52 T 29-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 SMALA_RS43265 ea1aa3d9975503f8e1fe6a76dfda2ed3 354 Gene3D G3DSA:1.10.443.10 157 351 1.3E-12 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 SMALA_RS43265 ea1aa3d9975503f8e1fe6a76dfda2ed3 354 SUPERFAMILY SSF56349 154 348 7.36E-21 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 SMALA_RS43265 ea1aa3d9975503f8e1fe6a76dfda2ed3 354 SUPERFAMILY SSF47823 43 113 5.1E-8 T 29-03-2018 IPR010998 Integrase, Lambda-type, N-terminal SMALA_RS43265 ea1aa3d9975503f8e1fe6a76dfda2ed3 354 Gene3D G3DSA:1.10.150.130 38 114 0.001 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal SMALA_RS28575 4ce56473696e1bf4951525acb590f0d2 494 Pfam PF08817 WXG100 protein secretion system (Wss), protein YukD 9 81 1.9E-19 T 29-03-2018 IPR024962 YukD-like SMALA_RS28575 4ce56473696e1bf4951525acb590f0d2 494 TIGRFAM TIGR03920 T7SS_EccD: type VII secretion integral membrane protein EccD 12 490 4.5E-55 T 29-03-2018 IPR006707 Type VII secretion system membrane protein EccD SMALA_RS28575 4ce56473696e1bf4951525acb590f0d2 494 PIRSF PIRSF017804 1 493 3.5E-116 T 29-03-2018 IPR006707 Type VII secretion system membrane protein EccD SMALA_RS41795 1b365d5397df3d42786d8c544e2516bf 210 Gene3D G3DSA:3.40.50.850 1 209 8.8E-32 T 29-03-2018 SMALA_RS41795 1b365d5397df3d42786d8c544e2516bf 210 SUPERFAMILY SSF52499 5 201 1.01E-34 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SMALA_RS41795 1b365d5397df3d42786d8c544e2516bf 210 Pfam PF00857 Isochorismatase family 13 185 1.5E-27 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SMALA_RS16820 1868e4ad85b7d1f69cbddecd21ea5cac 264 Gene3D G3DSA:3.40.1000.10 126 256 5.0E-17 T 29-03-2018 SMALA_RS34605 2f2e90eb0b4116e65955de16027ddce1 164 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 7 23 7.7E-15 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMALA_RS34605 2f2e90eb0b4116e65955de16027ddce1 164 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 34 53 7.7E-15 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMALA_RS34605 2f2e90eb0b4116e65955de16027ddce1 164 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 23 34 7.7E-15 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMALA_RS34605 2f2e90eb0b4116e65955de16027ddce1 164 Pfam PF01037 Lrp/AsnC ligand binding domain 74 146 8.2E-14 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain SMALA_RS34605 2f2e90eb0b4116e65955de16027ddce1 164 SUPERFAMILY SSF46785 6 66 6.04E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS34605 2f2e90eb0b4116e65955de16027ddce1 164 SUPERFAMILY SSF54909 69 151 4.96E-12 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel SMALA_RS34605 2f2e90eb0b4116e65955de16027ddce1 164 Gene3D G3DSA:1.10.10.10 2 62 4.2E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS34605 2f2e90eb0b4116e65955de16027ddce1 164 Pfam PF13404 AsnC-type helix-turn-helix domain 7 48 8.2E-17 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 SMALA_RS34605 2f2e90eb0b4116e65955de16027ddce1 164 Gene3D G3DSA:3.30.70.920 63 144 1.6E-18 T 29-03-2018 SMALA_RS34605 2f2e90eb0b4116e65955de16027ddce1 164 SMART SM00344 7 116 1.3E-31 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 SMALA_RS16500 50087811839a8dbd6f9f2bd3e6ea5002 140 SUPERFAMILY SSF53927 10 133 1.26E-38 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 SMALA_RS16500 50087811839a8dbd6f9f2bd3e6ea5002 140 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 17 105 1.6E-9 T 29-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain SMALA_RS16500 50087811839a8dbd6f9f2bd3e6ea5002 140 Gene3D G3DSA:3.40.140.10 1 134 1.6E-39 T 29-03-2018 SMALA_RS14450 6d00e8b57d5d9fd612655919dad7f7a6 296 SUPERFAMILY SSF53335 34 251 4.35E-30 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS14450 6d00e8b57d5d9fd612655919dad7f7a6 296 Gene3D G3DSA:3.40.50.150 20 287 2.5E-44 T 29-03-2018 SMALA_RS26725 e8f4f752bc611f4cca3962d528c3ae6d 359 SUPERFAMILY SSF47789 36 85 5.36E-6 T 29-03-2018 SMALA_RS26725 e8f4f752bc611f4cca3962d528c3ae6d 359 Gene3D G3DSA:1.10.150.20 26 86 2.5E-9 T 29-03-2018 SMALA_RS35585 d1f0d0dafb406b092391bf5fb6d12f3e 614 SUPERFAMILY SSF48208 141 611 4.54E-128 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 SMALA_RS35585 d1f0d0dafb406b092391bf5fb6d12f3e 614 Pfam PF00759 Glycosyl hydrolase family 9 142 606 3.6E-101 T 29-03-2018 IPR001701 Glycoside hydrolase family 9 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 SMALA_RS35585 d1f0d0dafb406b092391bf5fb6d12f3e 614 Pfam PF02927 Cellulase N-terminal ig-like domain 50 131 2.6E-24 T 29-03-2018 IPR004197 Cellulase, Ig-like domain GO:0005975|GO:0008810 SMALA_RS35585 d1f0d0dafb406b092391bf5fb6d12f3e 614 Gene3D G3DSA:2.60.40.10 48 138 3.8E-24 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS35585 d1f0d0dafb406b092391bf5fb6d12f3e 614 ProSitePatterns PS00698 Glycosyl hydrolases family 9 active sites signature 2. 583 601 - T 29-03-2018 IPR033126 Glycosyl hydrolases family 9, Asp/Glu active sites KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 SMALA_RS35585 d1f0d0dafb406b092391bf5fb6d12f3e 614 Gene3D G3DSA:1.50.10.10 140 614 5.0E-124 T 29-03-2018 SMALA_RS35585 d1f0d0dafb406b092391bf5fb6d12f3e 614 SUPERFAMILY SSF81296 40 137 7.7E-24 T 29-03-2018 IPR014756 Immunoglobulin E-set SMALA_RS17145 45e7f74bec61b8f97817bb337d3268f7 114 Gene3D G3DSA:2.30.30.410 25 114 3.3E-8 T 29-03-2018 SMALA_RS17145 45e7f74bec61b8f97817bb337d3268f7 114 Pfam PF08239 Bacterial SH3 domain 50 113 3.1E-8 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type SMALA_RS27340 60ea959d8f3961e19e7db2a1398026e1 634 SUPERFAMILY SSF69318 158 420 5.36E-12 T 29-03-2018 SMALA_RS27340 60ea959d8f3961e19e7db2a1398026e1 634 SUPERFAMILY SSF69318 497 575 5.36E-12 T 29-03-2018 SMALA_RS27340 60ea959d8f3961e19e7db2a1398026e1 634 Gene3D G3DSA:2.130.10.130 150 404 2.7E-10 T 29-03-2018 SMALA_RS27340 60ea959d8f3961e19e7db2a1398026e1 634 Gene3D G3DSA:2.60.40.10 57 143 1.2E-7 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS07915 32f615311340e3f9c22d665085e0a082 858 Pfam PF07510 Protein of unknown function (DUF1524) 415 557 3.3E-28 T 29-03-2018 IPR011089 Domain of unknown function DUF1524 SMALA_RS07915 32f615311340e3f9c22d665085e0a082 858 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 584 637 2.8E-7 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 SMALA_RS07915 32f615311340e3f9c22d665085e0a082 858 Pfam PF03235 Protein of unknown function DUF262 8 229 1.2E-35 T 29-03-2018 IPR004919 Domain of unknown function DUF262 SMALA_RS07915 32f615311340e3f9c22d665085e0a082 858 SUPERFAMILY SSF46767 582 637 1.15E-7 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 SMALA_RS07915 32f615311340e3f9c22d665085e0a082 858 Gene3D G3DSA:1.10.10.10 580 679 1.1E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS33725 81f92bd2e915ee1c368f0cb4acfcdd46 200 Pfam PF04186 FxsA cytoplasmic membrane protein 27 131 7.9E-28 T 29-03-2018 IPR007313 FxsA cytoplasmic membrane protein GO:0016020 SMALA_RS25390 043f97edb4afa469437a076a69b0d586 178 Gene3D G3DSA:2.60.40.10 9 113 2.8E-6 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS25390 043f97edb4afa469437a076a69b0d586 178 Gene3D G3DSA:2.60.40.10 114 177 3.8E-8 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS38080 847863b12c409dcdca89b799fe02fa80 209 SUPERFAMILY SSF46689 1 77 1.54E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS38080 847863b12c409dcdca89b799fe02fa80 209 SUPERFAMILY SSF48498 84 191 8.9E-20 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS38080 847863b12c409dcdca89b799fe02fa80 209 Gene3D G3DSA:1.10.357.10 60 192 1.1E-16 T 29-03-2018 SMALA_RS38080 847863b12c409dcdca89b799fe02fa80 209 Gene3D G3DSA:1.10.10.60 1 59 8.8E-15 T 29-03-2018 SMALA_RS38080 847863b12c409dcdca89b799fe02fa80 209 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 61 2.1E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS38080 847863b12c409dcdca89b799fe02fa80 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 3.4E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS38080 847863b12c409dcdca89b799fe02fa80 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 3.4E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS15975 446d9601f890f485a6783c4fde43604a 176 Pfam PF04138 GtrA-like protein 23 143 1.1E-21 T 29-03-2018 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 SMALA_RS21845 229a135c23f9e79e26bcffaca74da2d5 206 Pfam PF13238 AAA domain 23 176 8.6E-7 T 29-03-2018 SMALA_RS21845 229a135c23f9e79e26bcffaca74da2d5 206 Gene3D G3DSA:3.40.50.300 18 206 2.4E-38 T 29-03-2018 SMALA_RS21845 229a135c23f9e79e26bcffaca74da2d5 206 SUPERFAMILY SSF52540 17 204 5.74E-35 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS37035 9fc31cf988ea8f933ae3ccd1a776cb12 143 TIGRFAM TIGR02241 TIGR02241: conserved hypothetical phage tail region protein 6 140 9.1E-25 T 29-03-2018 IPR011747 Conserved hypothetical protein CHP02241 SMALA_RS37035 9fc31cf988ea8f933ae3ccd1a776cb12 143 Pfam PF06841 T4-like virus tail tube protein gp19 11 138 3.5E-27 T 29-03-2018 IPR010667 Bacteriophage T4, Gp19, tail tube GO:0005198 SMALA_RS14340 5870da90f250dee946dab2fc17eadf3f 100 SMART SM00530 20 74 2.4E-7 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS14340 5870da90f250dee946dab2fc17eadf3f 100 SUPERFAMILY SSF47413 8 79 8.89E-15 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS14340 5870da90f250dee946dab2fc17eadf3f 100 Pfam PF13560 Helix-turn-helix domain 16 72 1.3E-8 T 29-03-2018 SMALA_RS14340 5870da90f250dee946dab2fc17eadf3f 100 Gene3D G3DSA:1.10.260.40 7 76 1.3E-12 T 29-03-2018 SMALA_RS33555 12121249e54f3f43e401ef79504992a1 430 Gene3D G3DSA:1.20.91.10 237 329 5.6E-15 T 29-03-2018 SMALA_RS33555 12121249e54f3f43e401ef79504992a1 430 Pfam PF00999 Sodium/hydrogen exchanger family 15 398 2.8E-50 T 29-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 SMALA_RS01375 aa185f021b1db4097ad32b41a7b5aabc 287 Pfam PF04672 S-adenosyl methyltransferase 18 287 1.5E-110 T 29-03-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type SMALA_RS01375 aa185f021b1db4097ad32b41a7b5aabc 287 SUPERFAMILY SSF53335 26 263 3.18E-48 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS01375 aa185f021b1db4097ad32b41a7b5aabc 287 PIRSF PIRSF017393 5 287 5.0E-106 T 29-03-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type SMALA_RS01375 aa185f021b1db4097ad32b41a7b5aabc 287 Gene3D G3DSA:3.40.50.150 5 287 1.1E-58 T 29-03-2018 SMALA_RS40405 e41245040409820469a8c398e911afb5 438 Pfam PF13416 Bacterial extracellular solute-binding protein 57 359 9.5E-30 T 29-03-2018 SMALA_RS40405 e41245040409820469a8c398e911afb5 438 Gene3D G3DSA:3.40.190.10 37 221 2.1E-30 T 29-03-2018 SMALA_RS40405 e41245040409820469a8c398e911afb5 438 SUPERFAMILY SSF53850 24 434 4.55E-59 T 29-03-2018 SMALA_RS40405 e41245040409820469a8c398e911afb5 438 Gene3D G3DSA:3.40.190.10 222 392 3.2E-8 T 29-03-2018 SMALA_RS02175 b337c392e5caf366b377a1ac1883d65e 296 Pfam PF03707 Bacterial signalling protein N terminal repeat 56 113 4.8E-16 T 29-03-2018 IPR005330 MHYT domain SMALA_RS02175 b337c392e5caf366b377a1ac1883d65e 296 Pfam PF03707 Bacterial signalling protein N terminal repeat 120 174 8.9E-16 T 29-03-2018 IPR005330 MHYT domain SMALA_RS25975 c4e313cc3c28b60143cabe787fd5a4b5 534 SUPERFAMILY SSF53474 213 506 8.35E-25 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS25975 c4e313cc3c28b60143cabe787fd5a4b5 534 SUPERFAMILY SSF53474 107 170 8.35E-25 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS25975 c4e313cc3c28b60143cabe787fd5a4b5 534 Pfam PF08386 TAP-like protein 429 533 2.7E-33 T 29-03-2018 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal SMALA_RS25975 c4e313cc3c28b60143cabe787fd5a4b5 534 Gene3D G3DSA:3.40.50.1820 99 523 3.1E-45 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS22915 9804cb09dc9d721de4a689b00f500df9 102 Pfam PF00166 Chaperonin 10 Kd subunit 10 100 2.4E-32 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 SMALA_RS22915 9804cb09dc9d721de4a689b00f500df9 102 ProSitePatterns PS00681 Chaperonins cpn10 signature. 10 34 - T 29-03-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 SMALA_RS22915 9804cb09dc9d721de4a689b00f500df9 102 PRINTS PR00297 10kDa chaperonin signature 10 25 2.3E-30 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 SMALA_RS22915 9804cb09dc9d721de4a689b00f500df9 102 PRINTS PR00297 10kDa chaperonin signature 32 53 2.3E-30 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 SMALA_RS22915 9804cb09dc9d721de4a689b00f500df9 102 PRINTS PR00297 10kDa chaperonin signature 66 78 2.3E-30 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 SMALA_RS22915 9804cb09dc9d721de4a689b00f500df9 102 PRINTS PR00297 10kDa chaperonin signature 87 100 2.3E-30 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 SMALA_RS22915 9804cb09dc9d721de4a689b00f500df9 102 Hamap MF_00580 10 kDa chaperonin [groS]. 9 101 25.329 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 SMALA_RS22915 9804cb09dc9d721de4a689b00f500df9 102 Gene3D G3DSA:2.30.33.40 4 101 9.9E-38 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 SMALA_RS22915 9804cb09dc9d721de4a689b00f500df9 102 SMART SM00883 9 100 2.5E-50 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 SMALA_RS22915 9804cb09dc9d721de4a689b00f500df9 102 SUPERFAMILY SSF50129 9 101 3.06E-32 T 29-03-2018 IPR011032 GroES-like SMALA_RS36845 13add59e475ae2d16b9f2ac556f4089b 422 SUPERFAMILY SSF53300 40 226 9.22E-24 T 29-03-2018 IPR002035 von Willebrand factor, type A SMALA_RS36845 13add59e475ae2d16b9f2ac556f4089b 422 SMART SM00327 39 222 6.8E-16 T 29-03-2018 IPR002035 von Willebrand factor, type A SMALA_RS36845 13add59e475ae2d16b9f2ac556f4089b 422 Pfam PF13519 von Willebrand factor type A domain 42 158 2.3E-12 T 29-03-2018 IPR002035 von Willebrand factor, type A SMALA_RS36845 13add59e475ae2d16b9f2ac556f4089b 422 Gene3D G3DSA:3.40.50.410 39 227 1.4E-30 T 29-03-2018 IPR002035 von Willebrand factor, type A SMALA_RS06225 b4626dc0fa88b8a6d2856fcaf49b4198 316 Gene3D G3DSA:3.40.50.1820 13 312 9.3E-31 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS06225 b4626dc0fa88b8a6d2856fcaf49b4198 316 Pfam PF12697 Alpha/beta hydrolase family 41 296 8.9E-15 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS06225 b4626dc0fa88b8a6d2856fcaf49b4198 316 SUPERFAMILY SSF53474 13 142 6.95E-32 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS06225 b4626dc0fa88b8a6d2856fcaf49b4198 316 SUPERFAMILY SSF53474 231 311 6.95E-32 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS24695 ae38acdfde1e0f1b418d1a47ad5abcb2 686 Pfam PF02384 N-6 DNA Methylase 267 381 6.3E-5 T 29-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 SMALA_RS24695 ae38acdfde1e0f1b418d1a47ad5abcb2 686 SUPERFAMILY SSF53335 172 380 2.24E-23 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS24695 ae38acdfde1e0f1b418d1a47ad5abcb2 686 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 271 277 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 SMALA_RS24695 ae38acdfde1e0f1b418d1a47ad5abcb2 686 Gene3D G3DSA:3.40.50.150 180 404 1.5E-18 T 29-03-2018 SMALA_RS24695 ae38acdfde1e0f1b418d1a47ad5abcb2 686 Gene3D G3DSA:1.10.10.10 7 77 0.0018 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS21130 2715f056d24d3bfc6c30086274fc48e3 136 Pfam PF04149 Domain of unknown function (DUF397) 77 129 1.6E-19 T 29-03-2018 IPR007278 Domain of unknown function DUF397 SMALA_RS17015 533cf44e36f7185e59ac9416e33cc11c 391 Gene3D G3DSA:2.60.40.10 284 385 7.2E-7 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS34920 2ca4638fe5c547a8ac677de74c7f334d 467 SUPERFAMILY SSF48452 224 431 7.21E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS34920 2ca4638fe5c547a8ac677de74c7f334d 467 Gene3D G3DSA:1.25.40.10 14 460 7.4E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS07565 10a46eb8e2e92cd3e01669d51e00c194 190 Gene3D G3DSA:1.10.10.10 4 44 1.6E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS27505 6b45a3189584e35344b876d4bc08a300 185 SUPERFAMILY SSF69118 1 175 4.44E-34 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 SMALA_RS27505 6b45a3189584e35344b876d4bc08a300 185 Gene3D G3DSA:1.20.1290.10 33 180 4.0E-22 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 SMALA_RS27505 6b45a3189584e35344b876d4bc08a300 185 Pfam PF02627 Carboxymuconolactone decarboxylase family 45 109 1.1E-4 T 29-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SMALA_RS21180 d8ec1447c12cc1307cbd2828b1b1a480 139 Gene3D G3DSA:2.40.440.10 65 139 3.2E-12 T 29-03-2018 SMALA_RS21180 d8ec1447c12cc1307cbd2828b1b1a480 139 SUPERFAMILY SSF141523 69 137 3.4E-12 T 29-03-2018 SMALA_RS34500 bae95d73b298b12a6fa1bb9197d638e9 155 Gene3D G3DSA:1.10.10.10 7 155 2.8E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS34500 bae95d73b298b12a6fa1bb9197d638e9 155 SUPERFAMILY SSF46785 3 151 7.45E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS34500 bae95d73b298b12a6fa1bb9197d638e9 155 Pfam PF12802 MarR family 38 99 8.0E-10 T 29-03-2018 SMALA_RS34500 bae95d73b298b12a6fa1bb9197d638e9 155 SMART SM00347 33 136 6.8E-13 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS13440 fde2a1cd28f17893cfe942f510d44e6c 301 Gene3D G3DSA:1.10.3720.10 23 288 2.3E-52 T 29-03-2018 SMALA_RS13440 fde2a1cd28f17893cfe942f510d44e6c 301 SUPERFAMILY SSF161098 29 301 1.59E-72 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS13440 fde2a1cd28f17893cfe942f510d44e6c 301 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 294 9.2E-20 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS26390 2c7ba27651c72fe5d08131c48b907065 131 Gene3D G3DSA:3.10.180.10 1 131 5.9E-30 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS26390 2c7ba27651c72fe5d08131c48b907065 131 SUPERFAMILY SSF54593 1 130 3.76E-27 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS26390 2c7ba27651c72fe5d08131c48b907065 131 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 123 7.7E-16 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMALA_RS01865 fce9683abe93350791e273b70275bd17 192 SUPERFAMILY SSF52833 20 176 3.31E-25 T 29-03-2018 IPR012336 Thioredoxin-like fold SMALA_RS01865 fce9683abe93350791e273b70275bd17 192 Pfam PF13462 Thioredoxin 27 177 5.6E-18 T 29-03-2018 IPR012336 Thioredoxin-like fold SMALA_RS01865 fce9683abe93350791e273b70275bd17 192 Gene3D G3DSA:3.40.30.10 24 191 2.2E-31 T 29-03-2018 SMALA_RS34495 c3dcf8dbee644e3287b623ec9fd5ca21 420 SUPERFAMILY SSF56601 17 399 3.07E-56 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMALA_RS34495 c3dcf8dbee644e3287b623ec9fd5ca21 420 Gene3D G3DSA:3.40.710.10 19 397 1.8E-65 T 29-03-2018 SMALA_RS34495 c3dcf8dbee644e3287b623ec9fd5ca21 420 Pfam PF00144 Beta-lactamase 28 384 4.4E-50 T 29-03-2018 IPR001466 Beta-lactamase-related SMALA_RS16480 d441fdebf3e3b23254b34632c159bb44 254 SUPERFAMILY SSF53474 52 215 2.54E-24 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS16480 d441fdebf3e3b23254b34632c159bb44 254 Pfam PF12697 Alpha/beta hydrolase family 56 174 6.1E-7 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS16480 d441fdebf3e3b23254b34632c159bb44 254 Gene3D G3DSA:3.40.50.1820 10 222 3.7E-24 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS42520 96cedbd5dc703b91b702eeb09848db8a 276 Pfam PF00881 Nitroreductase family 38 191 2.0E-23 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 SMALA_RS42520 96cedbd5dc703b91b702eeb09848db8a 276 SUPERFAMILY SSF55469 30 273 7.46E-59 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMALA_RS42520 96cedbd5dc703b91b702eeb09848db8a 276 Gene3D G3DSA:3.40.109.10 28 275 2.7E-51 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMALA_RS42520 96cedbd5dc703b91b702eeb09848db8a 276 PIRSF PIRSF005426 27 275 1.3E-76 T 29-03-2018 IPR016446 Flavin oxidoreductase Frp family GO:0016491|GO:0055114 SMALA_RS10190 874c772ab350cfc61830bb50cf767642 206 Pfam PF04472 Cell division protein SepF 118 189 3.3E-27 T 29-03-2018 IPR007561 Cell division protein SepF/SepF-related GO:0090529 SMALA_RS10190 874c772ab350cfc61830bb50cf767642 206 Hamap MF_01197 Cell division protein SepF [sepF]. 2 197 22.653 T 29-03-2018 IPR023052 Cell division protein SepF GO:0090529 SMALA_RS19925 49f16cce5692c48c9f3cd836f2f12a97 98 PIRSF PIRSF030200 1 98 2.3E-44 T 29-03-2018 IPR009359 Phenylacetic acid degradation B SMALA_RS19925 49f16cce5692c48c9f3cd836f2f12a97 98 TIGRFAM TIGR02157 PA_CoA_Oxy2: phenylacetate-CoA oxygenase, PaaH subunit 9 97 9.7E-44 T 29-03-2018 IPR009359 Phenylacetic acid degradation B SMALA_RS19925 49f16cce5692c48c9f3cd836f2f12a97 98 Pfam PF06243 Phenylacetic acid degradation B 8 94 1.1E-39 T 29-03-2018 IPR009359 Phenylacetic acid degradation B SMALA_RS34375 6194ab8613c6cac54d1ae63c336ad2ac 257 Pfam PF09335 SNARE associated Golgi protein 79 196 9.2E-24 T 29-03-2018 IPR032816 SNARE associated Golgi protein SMALA_RS21325 a8af4f200a323ed35a40b1301218854f 165 Gene3D G3DSA:2.160.20.50 46 157 2.7E-5 T 29-03-2018 SMALA_RS30240 7a4bffe2433cce6a82874a804f8b2278 298 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 279 1.7E-18 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS30240 7a4bffe2433cce6a82874a804f8b2278 298 SUPERFAMILY SSF161098 89 277 1.13E-27 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS30240 7a4bffe2433cce6a82874a804f8b2278 298 Gene3D G3DSA:1.10.3720.10 40 292 3.0E-28 T 29-03-2018 SMALA_RS42250 76987913b98fea2305e92afa35a19e61 300 Pfam PF12146 Serine aminopeptidase, S33 64 271 1.1E-17 T 29-03-2018 IPR022742 Serine aminopeptidase, S33 SMALA_RS42250 76987913b98fea2305e92afa35a19e61 300 SUPERFAMILY SSF53474 219 289 2.36E-31 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS42250 76987913b98fea2305e92afa35a19e61 300 SUPERFAMILY SSF53474 6 150 2.36E-31 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS42250 76987913b98fea2305e92afa35a19e61 300 Gene3D G3DSA:3.40.50.1820 4 294 1.8E-32 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS05490 73c064d44964c519c417b1c84074001d 308 Gene3D G3DSA:3.40.50.720 1 300 5.7E-57 T 29-03-2018 SMALA_RS05490 73c064d44964c519c417b1c84074001d 308 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 92 103 1.2E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS05490 73c064d44964c519c417b1c84074001d 308 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 199 216 1.2E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS05490 73c064d44964c519c417b1c84074001d 308 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 137 153 1.2E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS05490 73c064d44964c519c417b1c84074001d 308 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 1.2E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS05490 73c064d44964c519c417b1c84074001d 308 SUPERFAMILY SSF51735 13 251 1.04E-50 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS05490 73c064d44964c519c417b1c84074001d 308 Pfam PF00106 short chain dehydrogenase 16 218 6.4E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS40645 38b1764569da016d7f0dca39c904352b 248 Pfam PF01670 Glycosyl hydrolase family 12 43 248 7.7E-67 T 29-03-2018 IPR002594 Glycoside hydrolase family 12 GO:0000272|GO:0008810 SMALA_RS40645 38b1764569da016d7f0dca39c904352b 248 Gene3D G3DSA:2.60.120.180 28 248 9.7E-72 T 29-03-2018 IPR013319 Glycoside hydrolase family 11/12 GO:0004553 MetaCyc: PWY-6784 SMALA_RS40645 38b1764569da016d7f0dca39c904352b 248 SUPERFAMILY SSF49899 31 248 1.63E-72 T 29-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain SMALA_RS39285 aa670d565324dcf3f7c5647361c3ba82 248 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 244 8.4E-61 T 29-03-2018 SMALA_RS39285 aa670d565324dcf3f7c5647361c3ba82 248 Gene3D G3DSA:3.40.50.720 1 246 5.6E-71 T 29-03-2018 SMALA_RS39285 aa670d565324dcf3f7c5647361c3ba82 248 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 182 3.5E-4 T 29-03-2018 SMALA_RS39285 aa670d565324dcf3f7c5647361c3ba82 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 4.5E-34 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS39285 aa670d565324dcf3f7c5647361c3ba82 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 4.5E-34 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS39285 aa670d565324dcf3f7c5647361c3ba82 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 4.5E-34 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS39285 aa670d565324dcf3f7c5647361c3ba82 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 4.5E-34 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS39285 aa670d565324dcf3f7c5647361c3ba82 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 4.5E-34 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS39285 aa670d565324dcf3f7c5647361c3ba82 248 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 138 166 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMALA_RS39285 aa670d565324dcf3f7c5647361c3ba82 248 SUPERFAMILY SSF51735 5 244 6.29E-75 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS20400 3378bc04087ffc3dbae8be0af2ae1f41 331 Gene3D G3DSA:3.10.310.10 155 321 1.2E-41 T 29-03-2018 SMALA_RS20400 3378bc04087ffc3dbae8be0af2ae1f41 331 Pfam PF02567 Phenazine biosynthesis-like protein 31 326 5.2E-63 T 29-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 SMALA_RS20400 3378bc04087ffc3dbae8be0af2ae1f41 331 PIRSF PIRSF016184 23 330 5.1E-54 T 29-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 SMALA_RS20400 3378bc04087ffc3dbae8be0af2ae1f41 331 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 26 325 3.2E-48 T 29-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 SMALA_RS20400 3378bc04087ffc3dbae8be0af2ae1f41 331 SUPERFAMILY SSF54506 26 327 1.15E-54 T 29-03-2018 SMALA_RS20400 3378bc04087ffc3dbae8be0af2ae1f41 331 Gene3D G3DSA:3.10.310.10 23 154 8.4E-27 T 29-03-2018 SMALA_RS10910 b3baf5e68d8db1452698ac14ac9c1730 308 SUPERFAMILY SSF56112 29 289 3.5E-30 T 29-03-2018 IPR011009 Protein kinase-like domain SMALA_RS10910 b3baf5e68d8db1452698ac14ac9c1730 308 Gene3D G3DSA:3.90.1200.10 110 280 1.5E-8 T 29-03-2018 SMALA_RS10910 b3baf5e68d8db1452698ac14ac9c1730 308 Pfam PF04655 Aminoglycoside/hydroxyurea antibiotic resistance kinase 42 289 3.2E-72 T 29-03-2018 IPR006748 Aminoglycoside/hydroxyurea antibiotic resistance kinase GO:0006468|GO:0016773|GO:0019748 SMALA_RS19580 6e72dfde3d9710b08043a81eefb14f1e 193 SUPERFAMILY SSF50249 6 193 1.71E-44 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMALA_RS19580 6e72dfde3d9710b08043a81eefb14f1e 193 Pfam PF00436 Single-strand binding protein family 7 107 8.2E-30 T 29-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 SMALA_RS19580 6e72dfde3d9710b08043a81eefb14f1e 193 Gene3D G3DSA:2.40.50.140 1 120 2.0E-41 T 29-03-2018 SMALA_RS19580 6e72dfde3d9710b08043a81eefb14f1e 193 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 6 118 4.9E-29 T 29-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 SMALA_RS19580 6e72dfde3d9710b08043a81eefb14f1e 193 Hamap MF_00984 Single-stranded DNA-binding protein. 4 113 30.118 T 29-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 SMALA_RS42735 1ad001196abfac0999b2b5f08368b96a 317 Pfam PF00248 Aldo/keto reductase family 16 313 2.2E-64 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS42735 1ad001196abfac0999b2b5f08368b96a 317 Gene3D G3DSA:3.20.20.100 1 317 1.9E-74 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS42735 1ad001196abfac0999b2b5f08368b96a 317 SUPERFAMILY SSF51430 4 315 1.44E-82 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS42735 1ad001196abfac0999b2b5f08368b96a 317 PRINTS PR00069 Aldo-keto reductase signature 109 127 4.5E-6 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMALA_RS42735 1ad001196abfac0999b2b5f08368b96a 317 PRINTS PR00069 Aldo-keto reductase signature 141 158 4.5E-6 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMALA_RS34955 55a5c5a6ad796ae816b489cdc98c82f0 284 Gene3D G3DSA:3.40.50.1460 5 284 3.0E-42 T 29-03-2018 SMALA_RS34955 55a5c5a6ad796ae816b489cdc98c82f0 284 Pfam PF00656 Caspase domain 18 264 3.3E-24 T 29-03-2018 SMALA_RS42785 053a1707a01ab43872e33cc6166f6c04 97 SUPERFAMILY SSF46894 19 82 6.8E-11 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS42785 053a1707a01ab43872e33cc6166f6c04 97 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 52 64 1.8E-5 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS42785 053a1707a01ab43872e33cc6166f6c04 97 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 22 36 1.8E-5 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS42785 053a1707a01ab43872e33cc6166f6c04 97 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 36 52 1.8E-5 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS42785 053a1707a01ab43872e33cc6166f6c04 97 SMART SM00421 19 76 9.8E-5 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS42785 053a1707a01ab43872e33cc6166f6c04 97 Gene3D G3DSA:1.10.10.10 12 86 6.3E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS42785 053a1707a01ab43872e33cc6166f6c04 97 Pfam PF00196 Bacterial regulatory proteins, luxR family 21 75 1.5E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMALA_RS11195 a6d83e6e230e44594e724403b799ef25 279 Gene3D G3DSA:3.90.550.10 2 218 1.1E-25 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS11195 a6d83e6e230e44594e724403b799ef25 279 SUPERFAMILY SSF53448 3 209 1.69E-35 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS11195 a6d83e6e230e44594e724403b799ef25 279 Pfam PF13632 Glycosyl transferase family group 2 75 211 7.6E-9 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 SMALA_RS01425 65a51747c0cfaa36a1813b98e68b0c80 413 SUPERFAMILY SSF53448 47 287 6.66E-30 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS01425 65a51747c0cfaa36a1813b98e68b0c80 413 Pfam PF13641 Glycosyltransferase like family 2 46 276 3.6E-26 T 29-03-2018 SMALA_RS01425 65a51747c0cfaa36a1813b98e68b0c80 413 Gene3D G3DSA:3.90.550.10 27 292 5.8E-33 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS11830 c46d7465b4edf46fde4a44d232b30466 509 Pfam PF00733 Asparagine synthase 243 464 3.8E-10 T 29-03-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 SMALA_RS11830 c46d7465b4edf46fde4a44d232b30466 509 Gene3D G3DSA:3.40.50.620 224 476 1.7E-16 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS11830 c46d7465b4edf46fde4a44d232b30466 509 SUPERFAMILY SSF52402 225 394 1.32E-11 T 29-03-2018 SMALA_RS21135 d4e0fa2dcea5755939ece8a350dd4e6d 695 Pfam PF01381 Helix-turn-helix 20 61 5.7E-8 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS21135 d4e0fa2dcea5755939ece8a350dd4e6d 695 Gene3D G3DSA:1.10.260.40 6 74 1.8E-10 T 29-03-2018 SMALA_RS21135 d4e0fa2dcea5755939ece8a350dd4e6d 695 SUPERFAMILY SSF47413 8 77 5.09E-8 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS21135 d4e0fa2dcea5755939ece8a350dd4e6d 695 SMART SM00530 10 65 1.2E-4 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS18185 2ef43e8df328833c5f79efe3c1233831 209 Gene3D G3DSA:1.10.10.10 1 97 8.9E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS18185 2ef43e8df328833c5f79efe3c1233831 209 Pfam PF03551 Transcriptional regulator PadR-like family 8 84 9.1E-10 T 29-03-2018 IPR005149 Transcription regulator PadR, N-terminal SMALA_RS18185 2ef43e8df328833c5f79efe3c1233831 209 SUPERFAMILY SSF46785 4 179 5.94E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS16905 c2bacbb264e0fbf1e4b0811a0efbb059 905 Gene3D G3DSA:1.10.890.20 562 599 0.0013 T 29-03-2018 IPR016089 Chalcone isomerase, orthogonal bundle domain KEGG: 00941+5.5.1.6|MetaCyc: PWY-2002|MetaCyc: PWY-5059|MetaCyc: PWY-6325|MetaCyc: PWY-6787|MetaCyc: PWY-7397 SMALA_RS16905 c2bacbb264e0fbf1e4b0811a0efbb059 905 Gene3D G3DSA:3.20.20.10 3 309 8.0E-4 T 29-03-2018 IPR029066 PLP-binding barrel SMALA_RS30960 6c80f7e31b8255009735c4ae3daeee82 742 Gene3D G3DSA:2.70.98.10 65 195 4.5E-5 T 29-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 SMALA_RS30960 6c80f7e31b8255009735c4ae3daeee82 742 Pfam PF17128 Domain of unknown function (DUF5107) 59 344 6.2E-33 T 29-03-2018 IPR033396 Domain of unknown function DUF5107 SMALA_RS30960 6c80f7e31b8255009735c4ae3daeee82 742 SUPERFAMILY SSF48452 482 551 8.54E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS30960 6c80f7e31b8255009735c4ae3daeee82 742 Gene3D G3DSA:1.25.40.10 371 729 3.0E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS17100 05338e974b49f63821e20ea52a9d0be0 418 Gene3D G3DSA:1.20.120.450 128 293 6.7E-29 T 29-03-2018 SMALA_RS17100 05338e974b49f63821e20ea52a9d0be0 418 Pfam PF13490 Putative zinc-finger 56 86 3.0E-6 T 29-03-2018 IPR027383 Putative zinc-finger SMALA_RS17100 05338e974b49f63821e20ea52a9d0be0 418 SUPERFAMILY SSF109854 127 293 4.58E-14 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes SMALA_RS32225 07b925d276313e6f48cb238aa38b0be6 241 SUPERFAMILY SSF53474 5 239 1.59E-32 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS32225 07b925d276313e6f48cb238aa38b0be6 241 PRINTS PR00412 Epoxide hydrolase signature 73 86 4.8E-6 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS32225 07b925d276313e6f48cb238aa38b0be6 241 PRINTS PR00412 Epoxide hydrolase signature 87 100 4.8E-6 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS32225 07b925d276313e6f48cb238aa38b0be6 241 PRINTS PR00412 Epoxide hydrolase signature 8 26 4.8E-6 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS32225 07b925d276313e6f48cb238aa38b0be6 241 PRINTS PR00412 Epoxide hydrolase signature 28 43 4.8E-6 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 SMALA_RS32225 07b925d276313e6f48cb238aa38b0be6 241 Pfam PF12697 Alpha/beta hydrolase family 5 233 1.2E-16 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS32225 07b925d276313e6f48cb238aa38b0be6 241 Gene3D G3DSA:3.40.50.1820 3 240 8.1E-27 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS32225 07b925d276313e6f48cb238aa38b0be6 241 PRINTS PR00111 Alpha/beta hydrolase fold signature 28 43 4.7E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS32225 07b925d276313e6f48cb238aa38b0be6 241 PRINTS PR00111 Alpha/beta hydrolase fold signature 73 86 4.7E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS32225 07b925d276313e6f48cb238aa38b0be6 241 PRINTS PR00111 Alpha/beta hydrolase fold signature 87 100 4.7E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS12615 dc32025c041a6b73b924259c13b6114c 401 Pfam PF13560 Helix-turn-helix domain 10 67 4.0E-10 T 29-03-2018 SMALA_RS12615 dc32025c041a6b73b924259c13b6114c 401 SUPERFAMILY SSF47413 5 68 1.63E-11 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMALA_RS12615 dc32025c041a6b73b924259c13b6114c 401 SMART SM00530 12 67 3.0E-11 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS12615 dc32025c041a6b73b924259c13b6114c 401 Gene3D G3DSA:1.10.260.40 1 83 2.6E-14 T 29-03-2018 SMALA_RS12615 dc32025c041a6b73b924259c13b6114c 401 Gene3D G3DSA:1.25.40.10 85 397 2.2E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS42875 7a005642ee2b191ffb357c6826af1c14 182 SUPERFAMILY SSF53597 3 179 1.1E-24 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 SMALA_RS42875 7a005642ee2b191ffb357c6826af1c14 182 Pfam PF01872 RibD C-terminal domain 2 172 1.1E-16 T 29-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 SMALA_RS42875 7a005642ee2b191ffb357c6826af1c14 182 Gene3D G3DSA:3.40.430.10 2 177 2.1E-29 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 SMALA_RS42955 f1d0f3a11937c9a93f8ee125ff28c981 329 Gene3D G3DSA:3.30.1120.50 237 291 0.0013 T 29-03-2018 SMALA_RS36375 1f0e95b0c18c3a0a171b5005af91aa70 125 Gene3D G3DSA:3.30.1390.10 70 120 0.0086 T 29-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like SMALA_RS36375 1f0e95b0c18c3a0a171b5005af91aa70 125 Pfam PF10025 Uncharacterized conserved protein (DUF2267) 4 119 1.4E-27 T 29-03-2018 IPR018727 Protein of unknown function DUF2267 SMALA_RS36375 1f0e95b0c18c3a0a171b5005af91aa70 125 Gene3D G3DSA:4.10.520.10 1 61 2.1E-4 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 SMALA_RS13900 4f598d4e3fe04230574a7600db85cc92 306 SUPERFAMILY SSF51658 11 289 1.66E-47 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SMALA_RS13900 4f598d4e3fe04230574a7600db85cc92 306 Pfam PF01261 Xylose isomerase-like TIM barrel 40 242 2.7E-29 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SMALA_RS13900 4f598d4e3fe04230574a7600db85cc92 306 Gene3D G3DSA:3.20.20.150 2 306 1.1E-47 T 29-03-2018 SMALA_RS15870 887273a19dba27af54eaebe441b157cc 1354 SUPERFAMILY SSF53448 150 291 8.04E-31 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS15870 887273a19dba27af54eaebe441b157cc 1354 SUPERFAMILY SSF53448 33 111 8.04E-31 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS15870 887273a19dba27af54eaebe441b157cc 1354 Gene3D G3DSA:3.90.550.10 4 303 3.2E-34 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS15870 887273a19dba27af54eaebe441b157cc 1354 Pfam PF13641 Glycosyltransferase like family 2 34 290 2.6E-14 T 29-03-2018 SMALA_RS17520 56c1bd11e2ca405a6e6d5d9837c2ab56 315 Gene3D G3DSA:3.90.550.10 1 315 7.5E-41 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS17520 56c1bd11e2ca405a6e6d5d9837c2ab56 315 Pfam PF00535 Glycosyl transferase family 2 36 150 1.1E-8 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 SMALA_RS17520 56c1bd11e2ca405a6e6d5d9837c2ab56 315 SUPERFAMILY SSF53448 35 272 1.41E-56 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS24655 547e1cc5f85d61a83db330d231b55e6d 136 Pfam PF00313 'Cold-shock' DNA-binding domain 4 65 1.7E-13 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMALA_RS24655 547e1cc5f85d61a83db330d231b55e6d 136 SUPERFAMILY SSF50249 3 68 2.45E-15 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SMALA_RS24655 547e1cc5f85d61a83db330d231b55e6d 136 Gene3D G3DSA:2.40.50.140 1 73 8.3E-18 T 29-03-2018 SMALA_RS24655 547e1cc5f85d61a83db330d231b55e6d 136 SMART SM00357 4 67 4.8E-10 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 SMALA_RS37555 6975e7724b499bad7906b2bf4cfbd0cf 470 SMART SM00100 96 217 7.2E-8 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain SMALA_RS37555 6975e7724b499bad7906b2bf4cfbd0cf 470 SUPERFAMILY SSF51206 91 210 4.84E-18 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like SMALA_RS37555 6975e7724b499bad7906b2bf4cfbd0cf 470 Gene3D G3DSA:2.60.120.10 89 229 1.5E-17 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SMALA_RS37555 6975e7724b499bad7906b2bf4cfbd0cf 470 Pfam PF00027 Cyclic nucleotide-binding domain 116 204 2.8E-11 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain SMALA_RS04955 8d5795b7aba06d290b6977f4af0a8b8e 172 Pfam PF09933 Predicted small integral membrane protein (DUF2165) 9 160 8.0E-56 T 29-03-2018 IPR018681 Protein of unknown function DUF2165, transmembrane SMALA_RS10460 b94e696223f4fadffa12e3fb7906be74 253 Gene3D G3DSA:3.60.21.10 1 252 1.9E-27 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SMALA_RS10460 b94e696223f4fadffa12e3fb7906be74 253 SUPERFAMILY SSF56300 1 46 1.75E-33 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SMALA_RS10460 b94e696223f4fadffa12e3fb7906be74 253 SUPERFAMILY SSF56300 83 244 1.75E-33 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SMALA_RS10460 b94e696223f4fadffa12e3fb7906be74 253 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 242 9.3E-8 T 29-03-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 SMALA_RS31085 b4d0960fcb5536053821c85015db4cc3 84 Gene3D G3DSA:1.10.1200.10 1 84 1.4E-10 T 29-03-2018 SMALA_RS31085 b4d0960fcb5536053821c85015db4cc3 84 SUPERFAMILY SSF47336 9 83 2.88E-9 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS31085 b4d0960fcb5536053821c85015db4cc3 84 ProSitePatterns PS00012 Phosphopantetheine attachment site. 37 52 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site SMALA_RS31085 b4d0960fcb5536053821c85015db4cc3 84 Pfam PF00550 Phosphopantetheine attachment site 11 76 3.0E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS28455 863621e4a7296b60362bf6ef3cc5b90b 170 Gene3D G3DSA:1.20.1260.10 38 165 0.0012 T 29-03-2018 IPR012347 Ferritin-related SMALA_RS13155 926ede496fa5a5754ee2f10b6275fbb1 400 Pfam PF01098 Cell cycle protein 35 395 3.3E-92 T 29-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 SMALA_RS13155 926ede496fa5a5754ee2f10b6275fbb1 400 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 354 378 - T 29-03-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 SMALA_RS13155 926ede496fa5a5754ee2f10b6275fbb1 400 TIGRFAM TIGR02210 rodA_shape: rod shape-determining protein RodA 34 396 6.9E-105 T 29-03-2018 IPR011923 Rod shape-determining protein RodA GO:0008360|GO:0016021 SMALA_RS25460 53b143f1bc0caffa969a3d8fe90a2556 302 Gene3D G3DSA:3.30.540.10 1 160 7.0E-12 T 29-03-2018 SMALA_RS25460 53b143f1bc0caffa969a3d8fe90a2556 302 SUPERFAMILY SSF56655 12 299 3.93E-23 T 29-03-2018 SMALA_RS25460 53b143f1bc0caffa969a3d8fe90a2556 302 Gene3D G3DSA:3.40.190.80 161 301 1.0E-21 T 29-03-2018 SMALA_RS25460 53b143f1bc0caffa969a3d8fe90a2556 302 Pfam PF00459 Inositol monophosphatase family 41 300 3.2E-12 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 SMALA_RS33055 3babdf2aa5d1cc7038b0b90e91958d6e 292 SUPERFAMILY SSF52540 112 284 4.56E-14 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS33055 3babdf2aa5d1cc7038b0b90e91958d6e 292 Pfam PF13671 AAA domain 113 245 9.4E-9 T 29-03-2018 SMALA_RS33055 3babdf2aa5d1cc7038b0b90e91958d6e 292 Gene3D G3DSA:3.40.50.300 107 287 7.6E-19 T 29-03-2018 SMALA_RS28100 a2b5dae090d510b8897d83aa6b9c1984 430 ProSitePatterns PS01219 Ammonium transporters signature. 162 187 - T 29-03-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 SMALA_RS28100 a2b5dae090d510b8897d83aa6b9c1984 430 Pfam PF00909 Ammonium Transporter Family 7 396 1.8E-125 T 29-03-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 SMALA_RS28100 a2b5dae090d510b8897d83aa6b9c1984 430 Gene3D G3DSA:1.10.3430.10 1 377 2.5E-132 T 29-03-2018 SMALA_RS28100 a2b5dae090d510b8897d83aa6b9c1984 430 SUPERFAMILY SSF111352 2 376 1.57E-124 T 29-03-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 SMALA_RS28100 a2b5dae090d510b8897d83aa6b9c1984 430 TIGRFAM TIGR00836 amt: ammonium transporter 5 396 7.8E-135 T 29-03-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 SMALA_RS14730 0c3de2503b25b945d83a27b63332dfd5 330 Gene3D G3DSA:3.10.129.10 14 154 2.5E-4 T 29-03-2018 SMALA_RS14730 0c3de2503b25b945d83a27b63332dfd5 330 Gene3D G3DSA:3.10.129.10 181 325 1.3E-9 T 29-03-2018 SMALA_RS14730 0c3de2503b25b945d83a27b63332dfd5 330 SUPERFAMILY SSF54637 200 323 3.73E-5 T 29-03-2018 IPR029069 HotDog domain SMALA_RS31350 749aeda317b7d80f0e362465cd621f54 331 Gene3D G3DSA:1.10.3470.10 50 328 2.1E-34 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SMALA_RS31350 749aeda317b7d80f0e362465cd621f54 331 Pfam PF02653 Branched-chain amino acid transport system / permease component 56 322 1.2E-41 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 SMALA_RS19535 adb4ceb1f2407d2d8d7670aeb0a3afb3 462 Pfam PF00144 Beta-lactamase 30 341 9.2E-60 T 29-03-2018 IPR001466 Beta-lactamase-related SMALA_RS19535 adb4ceb1f2407d2d8d7670aeb0a3afb3 462 SUPERFAMILY SSF56601 30 327 3.52E-71 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SMALA_RS19535 adb4ceb1f2407d2d8d7670aeb0a3afb3 462 Gene3D G3DSA:3.40.710.10 15 343 1.8E-72 T 29-03-2018 SMALA_RS20645 b710e9c5fb150940430156a1d8d11758 771 Pfam PF13183 4Fe-4S dicluster domain 299 407 3.3E-14 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain SMALA_RS20645 b710e9c5fb150940430156a1d8d11758 771 Pfam PF02754 Cysteine-rich domain 624 711 5.6E-20 T 29-03-2018 IPR004017 Cysteine-rich domain SMALA_RS20645 b710e9c5fb150940430156a1d8d11758 771 Pfam PF02754 Cysteine-rich domain 482 585 2.0E-12 T 29-03-2018 IPR004017 Cysteine-rich domain SMALA_RS20645 b710e9c5fb150940430156a1d8d11758 771 Gene3D G3DSA:1.10.1060.10 265 431 2.5E-32 T 29-03-2018 SMALA_RS20645 b710e9c5fb150940430156a1d8d11758 771 SUPERFAMILY SSF46548 375 421 1.22E-21 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 SMALA_RS20645 b710e9c5fb150940430156a1d8d11758 771 SUPERFAMILY SSF46548 287 338 1.22E-21 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 SMALA_RS20645 b710e9c5fb150940430156a1d8d11758 771 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 393 404 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site SMALA_RS20645 b710e9c5fb150940430156a1d8d11758 771 Gene3D G3DSA:1.20.950.20 1 250 4.9E-36 T 29-03-2018 SMALA_RS07815 6d96b047a716631638968a1e915683de 97 Gene3D G3DSA:2.40.50.140 18 92 1.4E-7 T 29-03-2018 SMALA_RS21925 ea6db4b2f37c0bdbcc6ae2af9214bb99 455 Pfam PF00656 Caspase domain 71 245 4.3E-11 T 29-03-2018 SMALA_RS21925 ea6db4b2f37c0bdbcc6ae2af9214bb99 455 SUPERFAMILY SSF52129 22 228 1.92E-9 T 29-03-2018 IPR029030 Caspase-like domain SMALA_RS21925 ea6db4b2f37c0bdbcc6ae2af9214bb99 455 Gene3D G3DSA:3.40.50.1460 1 254 1.2E-28 T 29-03-2018 SMALA_RS39960 b5dc528b5920ac68484547f656132abf 328 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 151 269 7.6E-12 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMALA_RS39960 b5dc528b5920ac68484547f656132abf 328 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 10 116 2.2E-6 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMALA_RS39960 b5dc528b5920ac68484547f656132abf 328 Gene3D G3DSA:3.10.180.10 2 147 1.9E-17 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS39960 b5dc528b5920ac68484547f656132abf 328 SUPERFAMILY SSF54593 3 269 2.58E-32 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS39960 b5dc528b5920ac68484547f656132abf 328 Gene3D G3DSA:3.10.180.10 150 328 2.2E-26 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS07210 f82f75b90cb45372a8eb78a5f84719f1 323 Pfam PF13280 WYL domain 148 318 7.0E-29 T 29-03-2018 IPR026881 WYL domain SMALA_RS07210 f82f75b90cb45372a8eb78a5f84719f1 323 PIRSF PIRSF016838 2 323 1.4E-78 T 29-03-2018 IPR028349 Protein PafC SMALA_RS25135 78291f64878e682975462d1dbcccaf07 504 Pfam PF00501 AMP-binding enzyme 11 413 4.2E-104 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS25135 78291f64878e682975462d1dbcccaf07 504 Pfam PF13193 AMP-binding enzyme C-terminal domain 422 497 2.7E-17 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS25135 78291f64878e682975462d1dbcccaf07 504 ProSitePatterns PS00455 Putative AMP-binding domain signature. 160 171 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS25135 78291f64878e682975462d1dbcccaf07 504 Gene3D G3DSA:3.30.300.30 406 504 3.5E-26 T 29-03-2018 SMALA_RS25135 78291f64878e682975462d1dbcccaf07 504 Gene3D G3DSA:3.40.50.980 2 165 6.9E-39 T 29-03-2018 SMALA_RS25135 78291f64878e682975462d1dbcccaf07 504 SUPERFAMILY SSF56801 5 503 2.35E-146 T 29-03-2018 SMALA_RS25135 78291f64878e682975462d1dbcccaf07 504 Gene3D G3DSA:2.30.38.10 321 405 2.3E-24 T 29-03-2018 SMALA_RS25135 78291f64878e682975462d1dbcccaf07 504 Gene3D G3DSA:3.40.50.980 166 320 1.5E-43 T 29-03-2018 SMALA_RS05355 bf5cc62cb813f43cc8f8bdb7cb3456aa 230 SUPERFAMILY SSF56317 5 224 1.7E-30 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMALA_RS05355 bf5cc62cb813f43cc8f8bdb7cb3456aa 230 Pfam PF00795 Carbon-nitrogen hydrolase 7 223 2.0E-14 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMALA_RS05355 bf5cc62cb813f43cc8f8bdb7cb3456aa 230 Gene3D G3DSA:3.60.110.10 1 229 1.4E-33 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMALA_RS25450 7b89da848171b6f802d52cca485e8d79 342 Gene3D G3DSA:3.40.50.720 36 322 2.1E-22 T 29-03-2018 SMALA_RS25450 7b89da848171b6f802d52cca485e8d79 342 SUPERFAMILY SSF51735 36 178 8.22E-41 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS25450 7b89da848171b6f802d52cca485e8d79 342 SUPERFAMILY SSF51735 207 316 8.22E-41 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS25450 7b89da848171b6f802d52cca485e8d79 342 Pfam PF04321 RmlD substrate binding domain 36 175 1.6E-27 T 29-03-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 SMALA_RS31800 055c68a62fc04d8190feba41c2909609 390 Gene3D G3DSA:3.60.60.10 123 373 3.1E-33 T 29-03-2018 SMALA_RS31800 055c68a62fc04d8190feba41c2909609 390 Pfam PF03417 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase 137 297 1.6E-14 T 29-03-2018 IPR005079 Peptidase C45 SMALA_RS05890 f57df61954797d3ce9a00e8572b37981 439 Gene3D G3DSA:1.10.600.10 117 429 9.4E-55 T 29-03-2018 IPR008949 Isoprenoid synthase domain SMALA_RS05890 f57df61954797d3ce9a00e8572b37981 439 SUPERFAMILY SSF48576 120 428 3.74E-37 T 29-03-2018 IPR008949 Isoprenoid synthase domain SMALA_RS03490 05e3de12c354a8b08b2fe1e304d60c9f 902 Pfam PF08376 Nitrate and nitrite sensing 58 300 2.0E-32 T 29-03-2018 IPR013587 Nitrate/nitrite sensing protein SMALA_RS03490 05e3de12c354a8b08b2fe1e304d60c9f 902 SUPERFAMILY SSF55874 506 628 7.07E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS03490 05e3de12c354a8b08b2fe1e304d60c9f 902 SMART SM00387 519 629 8.0E-6 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS03490 05e3de12c354a8b08b2fe1e304d60c9f 902 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 523 626 5.2E-6 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS03490 05e3de12c354a8b08b2fe1e304d60c9f 902 Pfam PF00672 HAMP domain 338 403 9.7E-7 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMALA_RS03490 05e3de12c354a8b08b2fe1e304d60c9f 902 Gene3D G3DSA:3.30.565.10 338 628 1.2E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS19445 6352ea6fb9bf7ad0b127463072ce3516 290 SMART SM01040 30 127 1.3E-22 T 29-03-2018 IPR003497 BRO N-terminal domain SMALA_RS19445 6352ea6fb9bf7ad0b127463072ce3516 290 Pfam PF02498 BRO family, N-terminal domain 31 122 8.0E-15 T 29-03-2018 IPR003497 BRO N-terminal domain SMALA_RS19445 6352ea6fb9bf7ad0b127463072ce3516 290 Gene3D G3DSA:1.10.10.10 125 285 0.0012 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS26700 4a02441166575854392de197bb7674df 363 Pfam PF14350 Beta protein 6 355 2.6E-44 T 29-03-2018 IPR025683 Protein beta SMALA_RS41540 5c4205b6b9e4123d4dd0fb404d2a2ac4 312 SUPERFAMILY SSF53474 27 311 1.51E-26 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS41540 5c4205b6b9e4123d4dd0fb404d2a2ac4 312 Gene3D G3DSA:3.40.50.1820 6 312 1.4E-24 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS34905 00157d46173a08228a467d178ecb9416 201 Gene3D G3DSA:3.40.50.300 10 159 7.7E-6 T 29-03-2018 SMALA_RS34905 00157d46173a08228a467d178ecb9416 201 SUPERFAMILY SSF52540 11 128 1.47E-5 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS30805 9901d426065e942f31cd16b01cbe621e 376 SUPERFAMILY SSF52540 114 343 1.15E-23 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS30805 9901d426065e942f31cd16b01cbe621e 376 SMART SM00382 120 307 2.7E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS30805 9901d426065e942f31cd16b01cbe621e 376 Pfam PF07728 AAA domain (dynein-related subfamily) 124 250 4.9E-7 T 29-03-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 SMALA_RS30805 9901d426065e942f31cd16b01cbe621e 376 Gene3D G3DSA:3.40.50.300 107 343 3.0E-26 T 29-03-2018 SMALA_RS29530 c838e7593bba6f2b04d2570f581b05c4 262 PIRSF PIRSF006648 1 261 1.9E-64 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMALA_RS29530 c838e7593bba6f2b04d2570f581b05c4 262 Pfam PF01061 ABC-2 type transporter 8 214 1.9E-30 T 29-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 SMALA_RS11130 a77af26d25bad2c043c602da43375a6a 325 Pfam PF03239 Iron permease FTR1 family 1 253 2.5E-66 T 29-03-2018 IPR004923 Iron permease FTR1/Fip1/EfeU GO:0005381|GO:0006827|GO:0016020|GO:0033573 SMALA_RS01620 977189b0f28071346f337734061e726c 207 Gene3D G3DSA:3.40.366.10 14 170 5.2E-10 T 29-03-2018 SMALA_RS01620 977189b0f28071346f337734061e726c 207 SUPERFAMILY SSF52151 83 164 5.23E-12 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMALA_RS21785 94bbc4b42b8dce8a8f5061558aea9fba 32 SMART SM01155 1 32 3.8E-5 T 29-03-2018 IPR013177 Domain of unknown function DUF1713 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS21785 94bbc4b42b8dce8a8f5061558aea9fba 32 Pfam PF08213 Mitochondrial domain of unknown function (DUF1713) 2 30 2.4E-9 T 29-03-2018 IPR013177 Domain of unknown function DUF1713 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMALA_RS08600 47b3e314958bef29eea30d9db5a3849e 66 Pfam PF05120 Gas vesicle protein G 2 63 2.0E-20 T 29-03-2018 IPR007804 Gas vesicle protein GvpG SMALA_RS35385 eef5e72e54106785d0fcefb42e469fc3 151 Pfam PF00932 Lamin Tail Domain 27 142 5.3E-25 T 29-03-2018 IPR001322 Lamin Tail Domain SMALA_RS35385 eef5e72e54106785d0fcefb42e469fc3 151 Gene3D G3DSA:2.60.40.1260 22 149 3.7E-22 T 29-03-2018 IPR001322 Lamin Tail Domain SMALA_RS35385 eef5e72e54106785d0fcefb42e469fc3 151 SUPERFAMILY SSF74853 52 142 6.02E-18 T 29-03-2018 IPR001322 Lamin Tail Domain SMALA_RS37705 b1bf28eb64e530026341a5e29f7473e7 754 Pfam PF17482 Phage tail sheath C-terminal domain 639 747 2.0E-18 T 29-03-2018 IPR020287 Tail sheath protein, C-terminal domain SMALA_RS37705 b1bf28eb64e530026341a5e29f7473e7 754 Pfam PF04984 Phage tail sheath protein subtilisin-like domain 491 638 2.5E-20 T 29-03-2018 IPR035089 Tail sheath protein, subtilisin-like domain SMALA_RS27220 bf0254886b4c0a5ed521de1ea3c5435e 261 SUPERFAMILY SSF53335 25 244 4.89E-39 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS27220 bf0254886b4c0a5ed521de1ea3c5435e 261 Gene3D G3DSA:3.40.50.150 3 245 4.6E-38 T 29-03-2018 SMALA_RS27220 bf0254886b4c0a5ed521de1ea3c5435e 261 Pfam PF08241 Methyltransferase domain 49 146 4.1E-21 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 SMALA_RS08725 a3da33ff327c9fa2de4575e017dab297 602 Gene3D G3DSA:1.50.10.10 196 553 6.1E-101 T 29-03-2018 SMALA_RS08725 a3da33ff327c9fa2de4575e017dab297 602 SUPERFAMILY SSF48208 196 595 5.1E-107 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 SMALA_RS08725 a3da33ff327c9fa2de4575e017dab297 602 Pfam PF00723 Glycosyl hydrolases family 15 222 553 5.3E-70 T 29-03-2018 IPR011613 Glycoside hydrolase family 15/Phosphorylase b kinase regulatory chain family Reactome: R-HSA-70221 SMALA_RS12445 9c6d7f26bf6c7f61a6202ea81a7088d9 182 SUPERFAMILY SSF52540 5 176 2.66E-19 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS12445 9c6d7f26bf6c7f61a6202ea81a7088d9 182 Pfam PF03029 Conserved hypothetical ATP binding protein 9 176 8.0E-19 T 29-03-2018 IPR004130 GPN-loop GTPase SMALA_RS12445 9c6d7f26bf6c7f61a6202ea81a7088d9 182 Gene3D G3DSA:3.40.50.300 2 182 1.2E-15 T 29-03-2018 SMALA_RS17290 c6cc908e78207c762608ce5a42e3fee0 334 Gene3D G3DSA:2.130.10.10 44 188 1.1E-8 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMALA_RS17290 c6cc908e78207c762608ce5a42e3fee0 334 Gene3D G3DSA:2.120.10.30 189 277 4.3E-5 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like SMALA_RS17290 c6cc908e78207c762608ce5a42e3fee0 334 SUPERFAMILY SSF75011 44 276 3.14E-16 T 29-03-2018 SMALA_RS14030 6c0ade286ae49bdd52ab13e4225e4bc1 246 Gene3D G3DSA:2.60.120.10 4 182 2.2E-28 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SMALA_RS14030 6c0ade286ae49bdd52ab13e4225e4bc1 246 SUPERFAMILY SSF51182 12 145 1.63E-13 T 29-03-2018 IPR011051 RmlC-like cupin domain SMALA_RS27020 2997603f024cdbbffb44e6e7c9dc24c4 276 Pfam PF12679 ABC-2 family transporter protein 84 276 2.3E-9 T 29-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 SMALA_RS04570 fea8e93e77281ea7a44259055a6751b3 1302 Pfam PF12770 CHAT domain 966 1295 1.7E-36 T 29-03-2018 IPR024983 CHAT domain SMALA_RS04570 fea8e93e77281ea7a44259055a6751b3 1302 Gene3D G3DSA:3.40.50.1460 1047 1299 3.1E-15 T 29-03-2018 SMALA_RS14585 70ebaa939a7040df16b9a9e7498cb6cb 328 Gene3D G3DSA:3.40.50.2300 115 276 6.2E-7 T 29-03-2018 SMALA_RS20100 328648a97291eb7c302897b6b5c24614 229 Pfam PF14021 Tuberculosis necrotizing toxin 136 227 6.6E-29 T 29-03-2018 IPR025331 Tuberculosis necrotizing toxin SMALA_RS41820 0301ecf372e2793606466783463ae5e5 315 SUPERFAMILY SSF56529 72 302 9.16E-61 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 SMALA_RS41820 0301ecf372e2793606466783463ae5e5 315 Gene3D G3DSA:3.90.850.10 30 301 8.0E-59 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 SMALA_RS41820 0301ecf372e2793606466783463ae5e5 315 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 77 300 1.6E-55 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 SMALA_RS05400 0650620b06466c4c41d6b5c61c831c17 324 Pfam PF16483 Beta-1,3-glucanase 126 228 1.1E-10 T 29-03-2018 IPR032477 Beta-1,3-glucanase, N-terminal KEGG: 00500+3.2.1.39 SMALA_RS05400 0650620b06466c4c41d6b5c61c831c17 324 Pfam PF16483 Beta-1,3-glucanase 235 322 1.4E-20 T 29-03-2018 IPR032477 Beta-1,3-glucanase, N-terminal KEGG: 00500+3.2.1.39 SMALA_RS18755 b58c3f7b0a8750e2fa52b62a7d3f9ec8 291 Pfam PF02104 SURF1 family 19 236 3.8E-26 T 29-03-2018 IPR002994 Surfeit locus 1/Shy1 GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMALA_RS27195 920c8e5cab3b4832d502aa88c4d551b3 270 Gene3D G3DSA:1.10.3720.10 5 259 9.0E-36 T 29-03-2018 SMALA_RS27195 920c8e5cab3b4832d502aa88c4d551b3 270 SUPERFAMILY SSF161098 3 266 1.09E-55 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS27195 920c8e5cab3b4832d502aa88c4d551b3 270 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 78 258 1.9E-12 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS18205 d022749d001b673b44b7576ea9582997 155 SUPERFAMILY SSF55874 45 152 1.77E-7 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS18205 d022749d001b673b44b7576ea9582997 155 Gene3D G3DSA:3.30.565.10 16 155 5.6E-11 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS18205 d022749d001b673b44b7576ea9582997 155 Pfam PF13581 Histidine kinase-like ATPase domain 25 147 4.7E-12 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS01385 dae076ee3845754d79a9fc4cd71c339e 396 PRINTS PR00359 B-class P450 signature 271 282 1.3E-60 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS01385 dae076ee3845754d79a9fc4cd71c339e 396 PRINTS PR00359 B-class P450 signature 190 212 1.3E-60 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS01385 dae076ee3845754d79a9fc4cd71c339e 396 PRINTS PR00359 B-class P450 signature 318 333 1.3E-60 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS01385 dae076ee3845754d79a9fc4cd71c339e 396 PRINTS PR00359 B-class P450 signature 135 151 1.3E-60 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS01385 dae076ee3845754d79a9fc4cd71c339e 396 PRINTS PR00359 B-class P450 signature 88 99 1.3E-60 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS01385 dae076ee3845754d79a9fc4cd71c339e 396 PRINTS PR00359 B-class P450 signature 290 317 1.3E-60 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS01385 dae076ee3845754d79a9fc4cd71c339e 396 PRINTS PR00359 B-class P450 signature 339 348 1.3E-60 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS01385 dae076ee3845754d79a9fc4cd71c339e 396 PRINTS PR00359 B-class P450 signature 152 167 1.3E-60 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS01385 dae076ee3845754d79a9fc4cd71c339e 396 PRINTS PR00359 B-class P450 signature 348 359 1.3E-60 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS01385 dae076ee3845754d79a9fc4cd71c339e 396 Gene3D G3DSA:1.10.630.10 2 396 8.8E-80 T 29-03-2018 SMALA_RS01385 dae076ee3845754d79a9fc4cd71c339e 396 PRINTS PR00385 P450 superfamily signature 348 359 1.2E-7 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS01385 dae076ee3845754d79a9fc4cd71c339e 396 PRINTS PR00385 P450 superfamily signature 339 348 1.2E-7 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS01385 dae076ee3845754d79a9fc4cd71c339e 396 PRINTS PR00385 P450 superfamily signature 236 253 1.2E-7 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS01385 dae076ee3845754d79a9fc4cd71c339e 396 PRINTS PR00385 P450 superfamily signature 271 282 1.2E-7 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS01385 dae076ee3845754d79a9fc4cd71c339e 396 SUPERFAMILY SSF48264 22 396 6.16E-99 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS01385 dae076ee3845754d79a9fc4cd71c339e 396 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 341 350 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMALA_RS01385 dae076ee3845754d79a9fc4cd71c339e 396 Pfam PF00067 Cytochrome P450 180 369 2.3E-23 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS22275 cb2afa95c85fdef787e051a25ac46164 541 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 97 227 5.0E-30 T 29-03-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS22275 cb2afa95c85fdef787e051a25ac46164 541 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 165 216 2.0E-15 T 29-03-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS22275 cb2afa95c85fdef787e051a25ac46164 541 SUPERFAMILY SSF143243 88 234 7.85E-32 T 29-03-2018 SMALA_RS02990 81655b02eca5ba437fa5325ee58156c2 340 Pfam PF16916 Dimerisation domain of Zinc Transporter 245 319 8.8E-15 T 29-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain SMALA_RS02990 81655b02eca5ba437fa5325ee58156c2 340 Gene3D G3DSA:1.20.1510.10 41 236 1.4E-38 T 29-03-2018 SMALA_RS02990 81655b02eca5ba437fa5325ee58156c2 340 SUPERFAMILY SSF161111 41 239 3.92E-47 T 29-03-2018 SMALA_RS02990 81655b02eca5ba437fa5325ee58156c2 340 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 42 319 1.5E-67 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 SMALA_RS02990 81655b02eca5ba437fa5325ee58156c2 340 Gene3D G3DSA:3.30.70.1350 237 321 2.4E-20 T 29-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain SMALA_RS02990 81655b02eca5ba437fa5325ee58156c2 340 SUPERFAMILY SSF160240 240 319 3.01E-16 T 29-03-2018 SMALA_RS02990 81655b02eca5ba437fa5325ee58156c2 340 Pfam PF01545 Cation efflux family 45 238 1.9E-39 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 SMALA_RS10180 504e59967899d71085a1333a8d0e5b70 399 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 3 38 1.4E-16 T 29-03-2018 IPR019933 DivIVA domain SMALA_RS10180 504e59967899d71085a1333a8d0e5b70 399 Gene3D G3DSA:1.20.1170.10 18 305 4.8E-8 T 29-03-2018 SMALA_RS10180 504e59967899d71085a1333a8d0e5b70 399 Pfam PF05103 DivIVA protein 3 64 6.6E-14 T 29-03-2018 IPR007793 DivIVA family SMALA_RS33730 3322ce750232b2d257306f283203e94f 124 Pfam PF13397 RNA polymerase-binding protein 4 107 1.6E-41 T 29-03-2018 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 SMALA_RS33730 3322ce750232b2d257306f283203e94f 124 Hamap MF_01483 RNA polymerase-binding protein RbpA [rbpA]. 16 120 26.324 T 29-03-2018 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 SMALA_RS12120 a1c1ef7e8e7c0823f42baa42a161cad3 422 Gene3D G3DSA:3.40.630.20 161 422 5.5E-39 T 29-03-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like SMALA_RS12120 a1c1ef7e8e7c0823f42baa42a161cad3 422 SUPERFAMILY SSF53182 340 417 1.83E-24 T 29-03-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like SMALA_RS12120 a1c1ef7e8e7c0823f42baa42a161cad3 422 SUPERFAMILY SSF53182 164 312 1.83E-24 T 29-03-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like SMALA_RS02855 d0b2fc4ef038746c6b37a9782b65dde6 129 SUPERFAMILY SSF57716 96 126 3.56E-6 T 29-03-2018 SMALA_RS02855 d0b2fc4ef038746c6b37a9782b65dde6 129 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 95 127 3.6E-9 T 29-03-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 SMALA_RS02855 d0b2fc4ef038746c6b37a9782b65dde6 129 SUPERFAMILY SSF109635 5 94 1.57E-5 T 29-03-2018 SMALA_RS28555 508888e0983f468c4d3be74e411cc03c 99 Pfam PF10824 Excreted virulence factor EspC, type VII ESX diderm 3 94 4.8E-5 T 29-03-2018 IPR022536 ESX-1 secretion-associated protein EspC GO:0009306 SMALA_RS28555 508888e0983f468c4d3be74e411cc03c 99 Gene3D G3DSA:1.10.287.1060 1 97 3.3E-9 T 29-03-2018 SMALA_RS40875 6ef3e3c1b4aa6ef09511254bb9046bc8 408 PRINTS PR00359 B-class P450 signature 288 315 6.5E-15 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS40875 6ef3e3c1b4aa6ef09511254bb9046bc8 408 PRINTS PR00359 B-class P450 signature 335 344 6.5E-15 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS40875 6ef3e3c1b4aa6ef09511254bb9046bc8 408 PRINTS PR00359 B-class P450 signature 140 156 6.5E-15 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMALA_RS40875 6ef3e3c1b4aa6ef09511254bb9046bc8 408 Gene3D G3DSA:1.10.630.10 5 397 3.3E-36 T 29-03-2018 SMALA_RS40875 6ef3e3c1b4aa6ef09511254bb9046bc8 408 SUPERFAMILY SSF48264 10 399 5.11E-53 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMALA_RS42405 5db9806b33f3a886e3c24b4ea870ad59 63 Pfam PF13602 Zinc-binding dehydrogenase 4 59 3.5E-8 T 29-03-2018 SMALA_RS42405 5db9806b33f3a886e3c24b4ea870ad59 63 Gene3D G3DSA:3.90.180.10 4 62 3.0E-8 T 29-03-2018 SMALA_RS03270 84d260af82543bd9820ca286831970ef 329 SUPERFAMILY SSF103481 48 144 9.81E-12 T 29-03-2018 SMALA_RS03270 84d260af82543bd9820ca286831970ef 329 Pfam PF00892 EamA-like transporter family 155 299 6.9E-15 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SMALA_RS03270 84d260af82543bd9820ca286831970ef 329 Pfam PF00892 EamA-like transporter family 14 143 1.4E-15 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SMALA_RS03270 84d260af82543bd9820ca286831970ef 329 SUPERFAMILY SSF103481 225 303 3.79E-9 T 29-03-2018 SMALA_RS09725 4eee5080a099a918cf17c1f3a8ea787c 314 SUPERFAMILY SSF159659 24 277 1.02E-71 T 29-03-2018 SMALA_RS09725 4eee5080a099a918cf17c1f3a8ea787c 314 PIRSF PIRSF028754 13 314 5.9E-104 T 29-03-2018 IPR008492 Protein of unknown function DUF774 SMALA_RS09725 4eee5080a099a918cf17c1f3a8ea787c 314 Gene3D G3DSA:1.10.287.100 235 276 2.2E-15 T 29-03-2018 SMALA_RS09725 4eee5080a099a918cf17c1f3a8ea787c 314 Pfam PF09754 PAC2 family 35 253 1.3E-36 T 29-03-2018 IPR019151 Proteasome assembly chaperone 2 SMALA_RS21525 6d2a2b69d7ac0144e4759f0bb84c3669 270 Gene3D G3DSA:1.10.10.10 110 226 4.7E-33 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS21525 6d2a2b69d7ac0144e4759f0bb84c3669 270 SMART SM00862 145 219 2.2E-30 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS21525 6d2a2b69d7ac0144e4759f0bb84c3669 270 SUPERFAMILY SSF46894 126 221 3.21E-30 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMALA_RS21525 6d2a2b69d7ac0144e4759f0bb84c3669 270 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 219 1.2E-28 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMALA_RS11200 62789e5d1978c1ec89dbe51df190c63b 207 SUPERFAMILY SSF46689 14 75 1.18E-10 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS11200 62789e5d1978c1ec89dbe51df190c63b 207 Gene3D G3DSA:1.10.357.10 71 203 6.2E-13 T 29-03-2018 SMALA_RS11200 62789e5d1978c1ec89dbe51df190c63b 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 30 71 6.2E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS11200 62789e5d1978c1ec89dbe51df190c63b 207 SUPERFAMILY SSF48498 85 200 4.45E-13 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS11200 62789e5d1978c1ec89dbe51df190c63b 207 Pfam PF16859 Bacterial transcriptional repressor C-terminal 84 195 2.8E-21 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS11200 62789e5d1978c1ec89dbe51df190c63b 207 Gene3D G3DSA:1.10.10.60 1 70 1.5E-13 T 29-03-2018 SMALA_RS39665 a49297dd5e87fb58d240d16edc8806a4 303 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 290 1.4E-22 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS39665 a49297dd5e87fb58d240d16edc8806a4 303 SUPERFAMILY SSF161098 94 280 3.53E-24 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS39665 a49297dd5e87fb58d240d16edc8806a4 303 Gene3D G3DSA:1.10.3720.10 23 288 4.4E-39 T 29-03-2018 SMALA_RS10900 f5cc06b17818da093dce171bb0e647a7 380 SUPERFAMILY SSF53686 10 377 3.27E-85 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMALA_RS10900 f5cc06b17818da093dce171bb0e647a7 380 Gene3D G3DSA:3.40.50.1100 187 380 9.0E-35 T 29-03-2018 SMALA_RS10900 f5cc06b17818da093dce171bb0e647a7 380 Gene3D G3DSA:3.40.50.1100 80 186 1.1E-24 T 29-03-2018 SMALA_RS10900 f5cc06b17818da093dce171bb0e647a7 380 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 71 366 4.1E-68 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMALA_RS13270 816dd44f38bf3c2f936ba79655e4eb78 380 Gene3D G3DSA:3.60.40.10 160 380 7.6E-15 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS13270 816dd44f38bf3c2f936ba79655e4eb78 380 SMART SM00331 170 379 3.6E-11 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS13270 816dd44f38bf3c2f936ba79655e4eb78 380 SUPERFAMILY SSF81606 201 362 1.26E-5 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS13270 816dd44f38bf3c2f936ba79655e4eb78 380 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 197 379 1.3E-32 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS02800 845de73b56f1a0566f291a468ef172c5 256 Gene3D G3DSA:3.40.50.10090 2 41 1.0E-7 T 29-03-2018 SMALA_RS02800 845de73b56f1a0566f291a468ef172c5 256 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 148 176 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMALA_RS02800 845de73b56f1a0566f291a468ef172c5 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 253 4.3E-58 T 29-03-2018 SMALA_RS02800 845de73b56f1a0566f291a468ef172c5 256 Gene3D G3DSA:3.40.50.720 42 256 2.2E-58 T 29-03-2018 SMALA_RS02800 845de73b56f1a0566f291a468ef172c5 256 SUPERFAMILY SSF51735 5 254 3.45E-71 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS02800 845de73b56f1a0566f291a468ef172c5 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 3.2E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS02800 845de73b56f1a0566f291a468ef172c5 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 3.2E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS02800 845de73b56f1a0566f291a468ef172c5 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 3.2E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS02800 845de73b56f1a0566f291a468ef172c5 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 3.2E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS02800 845de73b56f1a0566f291a468ef172c5 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 3.2E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS23860 8123b3508a37518bab42206790785a65 377 Pfam PF13190 PDGLE domain 286 362 2.2E-17 T 29-03-2018 IPR025937 PDGLE domain SMALA_RS23860 8123b3508a37518bab42206790785a65 377 Pfam PF01891 Cobalt uptake substrate-specific transmembrane region 1 206 5.3E-59 T 29-03-2018 IPR002751 Cobalamin (vitamin B12) biosynthesis CbiM family GO:0000041|GO:0016021 SMALA_RS23860 8123b3508a37518bab42206790785a65 377 ProDom PD486863 PRECURSOR CBIM SIGNAL COBALT MEMBRANE VITAMIN B12 BIOSYNTHESIS COBALAMIN ABC-TYPE 295 367 2.0E-24 T 29-03-2018 SMALA_RS00965 1b21fffc8f51d5767e61291643502051 445 Gene3D G3DSA:3.20.20.70 130 423 3.6E-13 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS00965 1b21fffc8f51d5767e61291643502051 445 SUPERFAMILY SSF102114 158 414 2.49E-10 T 29-03-2018 SMALA_RS37745 e452a07bf261ca01da09294895d2ad90 137 Pfam PF04965 Gene 25-like lysozyme 27 116 7.0E-20 T 29-03-2018 IPR007048 GpW/Gp25/anti-adapter protein IraD SMALA_RS37745 e452a07bf261ca01da09294895d2ad90 137 Gene3D G3DSA:3.10.450.40 1 129 2.2E-32 T 29-03-2018 SMALA_RS37745 e452a07bf261ca01da09294895d2ad90 137 SUPERFAMILY SSF160719 27 127 4.18E-24 T 29-03-2018 SMALA_RS41055 f0b24bf8838af83608f181c74a6c0dd5 278 Gene3D G3DSA:1.10.3720.10 1 266 4.6E-30 T 29-03-2018 SMALA_RS41055 f0b24bf8838af83608f181c74a6c0dd5 278 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 269 1.8E-14 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS41055 f0b24bf8838af83608f181c74a6c0dd5 278 SUPERFAMILY SSF161098 6 276 8.32E-53 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS02905 be68de5eb400f12bb1ecc9d56133cc4f 405 Gene3D G3DSA:3.40.50.2000 1 208 2.7E-20 T 29-03-2018 SMALA_RS02905 be68de5eb400f12bb1ecc9d56133cc4f 405 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 299 353 8.0E-9 T 29-03-2018 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 Reactome: R-HSA-156588 SMALA_RS02905 be68de5eb400f12bb1ecc9d56133cc4f 405 Gene3D G3DSA:3.40.50.2000 209 388 8.9E-35 T 29-03-2018 SMALA_RS02905 be68de5eb400f12bb1ecc9d56133cc4f 405 SUPERFAMILY SSF53756 2 403 6.87E-58 T 29-03-2018 SMALA_RS33485 20357daaffd074fbf40d16b5fe985328 152 SMART SM00903 1 148 9.1E-42 T 29-03-2018 IPR002563 Flavin reductase like domain GO:0010181 SMALA_RS33485 20357daaffd074fbf40d16b5fe985328 152 Gene3D G3DSA:2.30.110.10 1 149 1.3E-36 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS33485 20357daaffd074fbf40d16b5fe985328 152 SUPERFAMILY SSF50475 1 149 4.91E-37 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS33485 20357daaffd074fbf40d16b5fe985328 152 Pfam PF01613 Flavin reductase like domain 1 149 2.4E-32 T 29-03-2018 IPR002563 Flavin reductase like domain GO:0010181 SMALA_RS23535 c6d785a2a1a06d7ab2362fed49ed6a5d 149 Gene3D G3DSA:3.30.1330.90 16 148 4.0E-38 T 29-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 SMALA_RS23535 c6d785a2a1a06d7ab2362fed49ed6a5d 149 SUPERFAMILY SSF143548 22 143 3.92E-24 T 29-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 SMALA_RS23535 c6d785a2a1a06d7ab2362fed49ed6a5d 149 Pfam PF03315 Serine dehydratase beta chain 9 141 2.9E-40 T 29-03-2018 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 SMALA_RS19615 ec9c209f74f82a1b62889d4a60fb9613 235 Gene3D G3DSA:1.10.10.10 1 112 4.5E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS19615 ec9c209f74f82a1b62889d4a60fb9613 235 Pfam PF03551 Transcriptional regulator PadR-like family 12 95 4.8E-15 T 29-03-2018 IPR005149 Transcription regulator PadR, N-terminal SMALA_RS19615 ec9c209f74f82a1b62889d4a60fb9613 235 SUPERFAMILY SSF46785 8 184 1.78E-33 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS22360 1589b0d37a289545b0cd4d19f4320900 165 Pfam PF12098 Protein of unknown function (DUF3574) 61 165 7.4E-36 T 29-03-2018 IPR021957 Protein of unknown function DUF3574 SMALA_RS15925 a308c88d2ee535c4cb847fc3609f733b 543 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 144 304 1.0E-40 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain SMALA_RS15925 a308c88d2ee535c4cb847fc3609f733b 543 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 409 501 4.6E-11 T 29-03-2018 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain SMALA_RS15925 a308c88d2ee535c4cb847fc3609f733b 543 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 145 304 1.5E-42 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain SMALA_RS26525 c57beae2485a61a40a04cca67172da30 206 Pfam PF00881 Nitroreductase family 27 184 3.7E-17 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 SMALA_RS26525 c57beae2485a61a40a04cca67172da30 206 Gene3D G3DSA:3.40.109.10 17 204 1.7E-32 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMALA_RS26525 c57beae2485a61a40a04cca67172da30 206 SUPERFAMILY SSF55469 22 204 1.14E-41 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMALA_RS05940 2c7cc58cde43cd4abc90e7856e17f7dd 96 Pfam PF00550 Phosphopantetheine attachment site 32 83 6.1E-6 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS05940 2c7cc58cde43cd4abc90e7856e17f7dd 96 SUPERFAMILY SSF47336 23 88 8.24E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS05940 2c7cc58cde43cd4abc90e7856e17f7dd 96 Gene3D G3DSA:1.10.1200.10 14 91 3.1E-10 T 29-03-2018 SMALA_RS34910 703012a9a3e1eb46ea48a976d954b193 79 Pfam PF04149 Domain of unknown function (DUF397) 19 70 3.7E-13 T 29-03-2018 IPR007278 Domain of unknown function DUF397 SMALA_RS21490 96fe23e00c59160ea153cd7e01b6cd72 279 SMART SM00450 144 271 4.3E-21 T 29-03-2018 IPR001763 Rhodanese-like domain SMALA_RS21490 96fe23e00c59160ea153cd7e01b6cd72 279 SMART SM00450 8 122 1.6E-20 T 29-03-2018 IPR001763 Rhodanese-like domain SMALA_RS21490 96fe23e00c59160ea153cd7e01b6cd72 279 Gene3D G3DSA:3.40.250.10 1 141 3.0E-28 T 29-03-2018 IPR001763 Rhodanese-like domain SMALA_RS21490 96fe23e00c59160ea153cd7e01b6cd72 279 SUPERFAMILY SSF52821 4 140 2.23E-36 T 29-03-2018 IPR001763 Rhodanese-like domain SMALA_RS21490 96fe23e00c59160ea153cd7e01b6cd72 279 Pfam PF00581 Rhodanese-like domain 149 266 1.3E-15 T 29-03-2018 IPR001763 Rhodanese-like domain SMALA_RS21490 96fe23e00c59160ea153cd7e01b6cd72 279 Pfam PF00581 Rhodanese-like domain 10 118 2.4E-17 T 29-03-2018 IPR001763 Rhodanese-like domain SMALA_RS21490 96fe23e00c59160ea153cd7e01b6cd72 279 ProSitePatterns PS00683 Rhodanese C-terminal signature. 255 265 - T 29-03-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 SMALA_RS21490 96fe23e00c59160ea153cd7e01b6cd72 279 Gene3D G3DSA:3.40.250.10 150 279 4.6E-27 T 29-03-2018 IPR001763 Rhodanese-like domain SMALA_RS21490 96fe23e00c59160ea153cd7e01b6cd72 279 SUPERFAMILY SSF52821 149 276 8.51E-35 T 29-03-2018 IPR001763 Rhodanese-like domain SMALA_RS26310 0102d330a0ab2c20208c59d0b648e020 276 Gene3D G3DSA:1.10.3720.10 12 264 4.7E-45 T 29-03-2018 SMALA_RS26310 0102d330a0ab2c20208c59d0b648e020 276 SUPERFAMILY SSF161098 2 276 7.76E-72 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS26310 0102d330a0ab2c20208c59d0b648e020 276 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 90 263 1.4E-18 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS19885 88edfb1ea2d62ae746b835c46257a040 125 Gene3D G3DSA:1.10.10.10 8 124 3.6E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS19885 88edfb1ea2d62ae746b835c46257a040 125 SUPERFAMILY SSF46785 19 119 4.18E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS19885 88edfb1ea2d62ae746b835c46257a040 125 Pfam PF01638 HxlR-like helix-turn-helix 27 113 7.0E-25 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type SMALA_RS30275 48394ca6580e9b268d9e60d58a98d08a 61 Gene3D G3DSA:3.30.40.10 1 55 4.6E-4 T 29-03-2018 IPR013083 Zinc finger, RING/FYVE/PHD-type SMALA_RS41845 bc8bd36dd5046852761506a0385747c2 249 Pfam PF01925 Sulfite exporter TauE/SafE 8 243 2.1E-43 T 29-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 SMALA_RS19190 e51b606df7d441d12e70735592ba8d5f 283 SUPERFAMILY SSF51445 51 276 6.32E-29 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS19190 e51b606df7d441d12e70735592ba8d5f 283 Gene3D G3DSA:3.20.20.80 50 282 6.7E-49 T 29-03-2018 SMALA_RS19190 e51b606df7d441d12e70735592ba8d5f 283 Pfam PF08924 Domain of unknown function (DUF1906) 63 199 3.4E-32 T 29-03-2018 IPR015020 Protein of unknown function DUF1906 SMALA_RS31920 2eac3c26bc6ca6191ff8b4e593d1000b 240 Hamap MF_00801 Endonuclease V [nfi]. 18 238 31.427 T 29-03-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 SMALA_RS31920 2eac3c26bc6ca6191ff8b4e593d1000b 240 Pfam PF04493 Endonuclease V 47 228 4.7E-61 T 29-03-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 SMALA_RS00850 22152b109829d3b22e7986ea05d9a256 390 Pfam PF13088 BNR repeat-like domain 78 243 2.3E-7 T 29-03-2018 IPR011040 Sialidases KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 SMALA_RS00850 22152b109829d3b22e7986ea05d9a256 390 Gene3D G3DSA:2.120.10.10 37 383 3.7E-48 T 29-03-2018 SMALA_RS00850 22152b109829d3b22e7986ea05d9a256 390 SUPERFAMILY SSF50939 59 343 2.11E-16 T 29-03-2018 IPR011040 Sialidases KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 SMALA_RS32400 29fd56fa01583750444001a1ebf8c97c 68 SUPERFAMILY SSF50118 1 63 1.96E-24 T 29-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor SMALA_RS32400 29fd56fa01583750444001a1ebf8c97c 68 Pfam PF08940 Domain of unknown function (DUF1918) 1 58 3.0E-28 T 29-03-2018 IPR015035 Domain of unknown function DUF1918 SMALA_RS19435 fc5b04575174c7a5eba13d72f2008281 403 Gene3D G3DSA:3.60.21.10 117 399 5.3E-33 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SMALA_RS19435 fc5b04575174c7a5eba13d72f2008281 403 SUPERFAMILY SSF56300 132 390 1.29E-34 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SMALA_RS19435 fc5b04575174c7a5eba13d72f2008281 403 PRINTS PR00114 Serine/threonine phosphatase family signature 171 198 2.2E-5 T 29-03-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS19435 fc5b04575174c7a5eba13d72f2008281 403 PRINTS PR00114 Serine/threonine phosphatase family signature 134 161 2.2E-5 T 29-03-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SMALA_RS19435 fc5b04575174c7a5eba13d72f2008281 403 Pfam PF00149 Calcineurin-like phosphoesterase 134 351 1.2E-8 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 SMALA_RS12605 295cb5d495fb8070d51f3ccc866c2428 509 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 85 232 3.0E-9 T 29-03-2018 SMALA_RS40655 c377690aa08034fe4497bccd2d13ef50 176 Pfam PF04343 Protein of unknown function, DUF488 18 136 2.5E-25 T 29-03-2018 IPR007438 Protein of unknown function DUF488 SMALA_RS40655 c377690aa08034fe4497bccd2d13ef50 176 PIRSF PIRSF024492 2 176 2.4E-46 T 29-03-2018 IPR014519 Uncharacterised conserved protein UCP024492 SMALA_RS01205 a831e9f2131e196d96fd7700e0e2bea3 63 TIGRFAM TIGR04186 GRASP_targ: putative ATP-grasp target RiPP 1 63 1.4E-11 T 29-03-2018 IPR026496 Putative ATP-grasp target RiPP SMALA_RS01205 a831e9f2131e196d96fd7700e0e2bea3 63 Pfam PF14404 Ribosomally synthesized peptide in Streptomyces species 1 63 5.8E-35 T 29-03-2018 IPR025744 Ribosomally synthesised peptide in Streptomyces SMALA_RS31250 255b704bc32789013b0417cc81a6cbc1 608 SUPERFAMILY SSF56801 17 294 3.14E-113 T 29-03-2018 SMALA_RS31250 255b704bc32789013b0417cc81a6cbc1 608 SUPERFAMILY SSF56801 348 606 3.14E-113 T 29-03-2018 SMALA_RS31250 255b704bc32789013b0417cc81a6cbc1 608 Gene3D G3DSA:2.30.38.10 399 470 6.2E-21 T 29-03-2018 SMALA_RS31250 255b704bc32789013b0417cc81a6cbc1 608 Pfam PF00501 AMP-binding enzyme 24 477 5.0E-94 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS31250 255b704bc32789013b0417cc81a6cbc1 608 Gene3D G3DSA:3.40.50.980 190 398 8.6E-40 T 29-03-2018 SMALA_RS31250 255b704bc32789013b0417cc81a6cbc1 608 ProSitePatterns PS00455 Putative AMP-binding domain signature. 184 195 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS31250 255b704bc32789013b0417cc81a6cbc1 608 Gene3D G3DSA:3.40.50.980 13 189 5.1E-38 T 29-03-2018 SMALA_RS31250 255b704bc32789013b0417cc81a6cbc1 608 Gene3D G3DSA:3.30.300.30 472 608 1.6E-15 T 29-03-2018 SMALA_RS33145 9232a98d2e6b9cd22700772e2362a76e 720 Hamap MF_00983 Probable primosomal protein N' [priA]. 57 719 20.472 T 29-03-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 SMALA_RS33145 9232a98d2e6b9cd22700772e2362a76e 720 Gene3D G3DSA:3.40.50.300 223 315 3.8E-5 T 29-03-2018 SMALA_RS33145 9232a98d2e6b9cd22700772e2362a76e 720 SUPERFAMILY SSF52540 225 315 1.25E-6 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS18655 643f566c81538226f478a486371ce3f4 51 Pfam PF13783 Domain of unknown function (DUF4177) 4 39 6.3E-6 T 29-03-2018 IPR025234 Protein of unknown function DUF4177 SMALA_RS22030 833196c9518cc2d41a7c645664564b6a 338 SUPERFAMILY SSF53474 62 331 1.38E-41 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS22030 833196c9518cc2d41a7c645664564b6a 338 Pfam PF00756 Putative esterase 70 331 3.2E-40 T 29-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 SMALA_RS22030 833196c9518cc2d41a7c645664564b6a 338 Gene3D G3DSA:3.40.50.1820 3 337 2.0E-41 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS03125 5ded57d86389db50bbec7179e74a4c81 423 SUPERFAMILY SSF51905 288 389 3.97E-62 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS03125 5ded57d86389db50bbec7179e74a4c81 423 SUPERFAMILY SSF51905 7 182 3.97E-62 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS03125 5ded57d86389db50bbec7179e74a4c81 423 Gene3D G3DSA:3.50.50.60 2 397 6.0E-51 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS03125 5ded57d86389db50bbec7179e74a4c81 423 Pfam PF01494 FAD binding domain 7 364 9.6E-22 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 SMALA_RS03125 5ded57d86389db50bbec7179e74a4c81 423 SUPERFAMILY SSF54373 187 283 2.9E-14 T 29-03-2018 SMALA_RS03125 5ded57d86389db50bbec7179e74a4c81 423 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 316 332 1.3E-20 T 29-03-2018 SMALA_RS03125 5ded57d86389db50bbec7179e74a4c81 423 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 301 316 1.3E-20 T 29-03-2018 SMALA_RS03125 5ded57d86389db50bbec7179e74a4c81 423 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 8 30 1.3E-20 T 29-03-2018 SMALA_RS03125 5ded57d86389db50bbec7179e74a4c81 423 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 161 176 1.3E-20 T 29-03-2018 SMALA_RS42815 78001ad3cee953954058ae9efa81d299 114 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 20 90 2.7E-17 T 29-03-2018 IPR025161 Putative transposase IS4/IS5 family SMALA_RS38030 b7378e23ccd5ce0891ce89eb6a7949f7 323 SUPERFAMILY SSF52283 34 125 4.68E-12 T 29-03-2018 SMALA_RS38030 b7378e23ccd5ce0891ce89eb6a7949f7 323 SUPERFAMILY SSF51735 96 289 2.19E-46 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS38030 b7378e23ccd5ce0891ce89eb6a7949f7 323 Gene3D G3DSA:3.40.50.720 2 108 2.5E-15 T 29-03-2018 SMALA_RS38030 b7378e23ccd5ce0891ce89eb6a7949f7 323 Gene3D G3DSA:3.40.50.720 109 292 1.6E-50 T 29-03-2018 SMALA_RS38030 b7378e23ccd5ce0891ce89eb6a7949f7 323 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 104 288 1.5E-45 T 29-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 SMALA_RS38030 b7378e23ccd5ce0891ce89eb6a7949f7 323 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 47 320 2.3E-7 T 29-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 SMALA_RS27480 59232c82d5a6324ea61b4a197b550879 448 Gene3D G3DSA:3.40.50.10330 126 254 1.2E-20 T 29-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 SMALA_RS27480 59232c82d5a6324ea61b4a197b550879 448 Pfam PF00781 Diacylglycerol kinase catalytic domain 132 249 1.2E-18 T 29-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 SMALA_RS27480 59232c82d5a6324ea61b4a197b550879 448 SUPERFAMILY SSF111331 130 412 8.28E-51 T 29-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain SMALA_RS41980 6db5331e97912f49babf3f02a82fe27a 448 Gene3D G3DSA:3.40.50.410 224 410 7.8E-8 T 29-03-2018 IPR002035 von Willebrand factor, type A SMALA_RS41980 6db5331e97912f49babf3f02a82fe27a 448 Pfam PF01882 Protein of unknown function DUF58 212 297 1.1E-13 T 29-03-2018 IPR002881 Domain of unknown function DUF58 SMALA_RS02470 5ffdf7781f3d2933e48db244e78cf8d9 152 Pfam PF00376 MerR family regulatory protein 16 54 6.9E-14 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS02470 5ffdf7781f3d2933e48db244e78cf8d9 152 Gene3D G3DSA:1.10.1660.10 72 151 5.5E-8 T 29-03-2018 SMALA_RS02470 5ffdf7781f3d2933e48db244e78cf8d9 152 SUPERFAMILY SSF46955 15 125 2.45E-24 T 29-03-2018 IPR009061 Putative DNA-binding domain SMALA_RS02470 5ffdf7781f3d2933e48db244e78cf8d9 152 Gene3D G3DSA:1.10.1660.10 12 71 3.7E-17 T 29-03-2018 SMALA_RS02470 5ffdf7781f3d2933e48db244e78cf8d9 152 SMART SM00422 15 85 8.4E-13 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMALA_RS19985 2a2d3a89384b1247f0516bb0460d87a8 303 SUPERFAMILY SSF53448 1 211 3.03E-23 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS19985 2a2d3a89384b1247f0516bb0460d87a8 303 Gene3D G3DSA:3.90.550.10 1 222 1.2E-26 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS19985 2a2d3a89384b1247f0516bb0460d87a8 303 Pfam PF12804 MobA-like NTP transferase domain 1 162 5.4E-27 T 29-03-2018 IPR025877 MobA-like NTP transferase SMALA_RS03120 bfca303c2212e40985883e894e94fdc4 343 SUPERFAMILY SSF144052 147 275 1.83E-6 T 29-03-2018 SMALA_RS11925 e76e9c4bb7d8e321d0efff3203845c0a 191 Pfam PF02342 TerD domain 1 186 1.4E-82 T 29-03-2018 IPR003325 TerD domain GO:0006950 SMALA_RS11925 e76e9c4bb7d8e321d0efff3203845c0a 191 Gene3D G3DSA:2.60.60.30 18 184 2.3E-65 T 29-03-2018 SMALA_RS19025 98f4e43f0311a9abd0fdcfa9989898d5 166 Gene3D G3DSA:3.40.140.10 20 166 3.4E-48 T 29-03-2018 SMALA_RS19025 98f4e43f0311a9abd0fdcfa9989898d5 166 Pfam PF14437 MafB19-like deaminase 23 165 1.9E-29 T 29-03-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 SMALA_RS19025 98f4e43f0311a9abd0fdcfa9989898d5 166 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 25 164 45.584 T 29-03-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 SMALA_RS19025 98f4e43f0311a9abd0fdcfa9989898d5 166 SUPERFAMILY SSF53927 21 165 1.84E-53 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 SMALA_RS19025 98f4e43f0311a9abd0fdcfa9989898d5 166 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 71 108 - T 29-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 SMALA_RS09220 80a0948688cc65b9188dd1ce8e9b6dbc 308 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 266 300 1.1E-4 T 29-03-2018 SMALA_RS03355 cab965e671113718507b03894718a7bb 110 PIRSF PIRSF018579 1 110 3.9E-46 T 29-03-2018 IPR009709 Protein of unknown function DUF1290 SMALA_RS03355 cab965e671113718507b03894718a7bb 110 Pfam PF06947 Protein of unknown function (DUF1290) 21 108 1.0E-34 T 29-03-2018 IPR009709 Protein of unknown function DUF1290 SMALA_RS27210 c7614bd5b45bfbec23cf6a9b687be39c 409 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 161 313 3.1E-41 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain SMALA_RS27210 c7614bd5b45bfbec23cf6a9b687be39c 409 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 161 313 2.7E-45 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain SMALA_RS28420 d67b57ae7dacbdd7c42c58a9055d7e84 433 Gene3D G3DSA:2.30.42.10 25 246 5.2E-13 T 29-03-2018 SMALA_RS28420 d67b57ae7dacbdd7c42c58a9055d7e84 433 Pfam PF02163 Peptidase family M50 13 386 2.9E-48 T 29-03-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889|Reactome: R-MMU-8963889 SMALA_RS28420 d67b57ae7dacbdd7c42c58a9055d7e84 433 SUPERFAMILY SSF50156 128 236 1.58E-14 T 29-03-2018 IPR001478 PDZ domain GO:0005515 SMALA_RS29220 4491449563d8287e8bf58cce66485920 261 Pfam PF12502 Protein of unknown function (DUF3710) 55 228 2.3E-60 T 29-03-2018 IPR022183 Protein of unknown function DUF3710 SMALA_RS15515 9b17d0fb5180eb6729f0586acb7e3a77 303 PIRSF PIRSF003097 1 303 3.2E-76 T 29-03-2018 IPR004513 Cell division protein FtsX GO:0007049|GO:0016021 SMALA_RS37020 941b17a53669fead6705383986dde4be 91 Pfam PF05488 PAAR motif 7 81 3.6E-21 T 29-03-2018 IPR008727 PAAR motif SMALA_RS36435 fd9f2b733c80b5707c4e939a33539af6 379 Gene3D G3DSA:3.20.20.30 7 376 2.0E-78 T 29-03-2018 SMALA_RS36435 fd9f2b733c80b5707c4e939a33539af6 379 SUPERFAMILY SSF51679 1 372 4.24E-73 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS36435 fd9f2b733c80b5707c4e939a33539af6 379 Pfam PF00296 Luciferase-like monooxygenase 1 336 1.9E-45 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS35700 31ff99fbc202faa7cf3304167dd281ce 379 SUPERFAMILY SSF51556 6 169 2.18E-13 T 29-03-2018 IPR032466 Metal-dependent hydrolase SMALA_RS35700 31ff99fbc202faa7cf3304167dd281ce 379 SUPERFAMILY SSF51556 199 371 2.18E-13 T 29-03-2018 IPR032466 Metal-dependent hydrolase SMALA_RS35700 31ff99fbc202faa7cf3304167dd281ce 379 Gene3D G3DSA:3.20.20.140 112 371 4.5E-70 T 29-03-2018 SMALA_RS11510 c2a985c9491f52a3d7d241abf6d1f8d3 209 Gene3D G3DSA:2.60.40.200 74 207 2.4E-16 T 29-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 SMALA_RS11510 c2a985c9491f52a3d7d241abf6d1f8d3 209 SUPERFAMILY SSF49329 90 206 8.51E-15 T 29-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 SMALA_RS11510 c2a985c9491f52a3d7d241abf6d1f8d3 209 Pfam PF00080 Copper/zinc superoxide dismutase (SODC) 91 205 2.7E-10 T 29-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 SMALA_RS03655 a540073d5636c776ca6fd97935473bf7 395 SUPERFAMILY SSF48576 22 344 4.03E-43 T 29-03-2018 IPR008949 Isoprenoid synthase domain SMALA_RS03655 a540073d5636c776ca6fd97935473bf7 395 Gene3D G3DSA:1.10.600.10 18 339 1.4E-62 T 29-03-2018 IPR008949 Isoprenoid synthase domain SMALA_RS07370 24eba30ce5b0d44ef75e22b033054cc3 283 Gene3D G3DSA:3.20.20.140 1 283 4.0E-47 T 29-03-2018 SMALA_RS07370 24eba30ce5b0d44ef75e22b033054cc3 283 SUPERFAMILY SSF51556 4 281 9.98E-74 T 29-03-2018 IPR032466 Metal-dependent hydrolase SMALA_RS07370 24eba30ce5b0d44ef75e22b033054cc3 283 Pfam PF04909 Amidohydrolase 5 281 5.2E-47 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 SMALA_RS03070 2119245ad4e10ce0c661d8c2e06e757b 359 Pfam PF06089 L-asparaginase II 32 334 6.4E-109 T 29-03-2018 IPR010349 L-asparaginase II SMALA_RS34385 d66d5fe758eb0091221cdb78a4895b08 281 Gene3D G3DSA:3.40.50.150 3 270 3.8E-46 T 29-03-2018 SMALA_RS34385 d66d5fe758eb0091221cdb78a4895b08 281 SUPERFAMILY SSF53335 25 233 3.1E-29 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS24520 04a1a51cebd9118ac3fc6500e121df5d 313 Pfam PF00005 ABC transporter 22 163 3.2E-26 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS24520 04a1a51cebd9118ac3fc6500e121df5d 313 SUPERFAMILY SSF52540 7 225 3.16E-54 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS24520 04a1a51cebd9118ac3fc6500e121df5d 313 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMALA_RS24520 04a1a51cebd9118ac3fc6500e121df5d 313 SMART SM00382 31 249 3.7E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS24520 04a1a51cebd9118ac3fc6500e121df5d 313 Gene3D G3DSA:3.40.50.300 4 256 4.8E-59 T 29-03-2018 SMALA_RS32660 e6dc33117fd74eec8ad7b9c9d8f6eee4 470 Pfam PF05133 Phage portal protein, SPP1 Gp6-like 28 457 1.9E-12 T 29-03-2018 IPR021145 Portal protein SMALA_RS10280 ec260843b2bf0eaf5d953c124d9571f1 131 Pfam PF11239 Protein of unknown function (DUF3040) 1 80 6.8E-29 T 29-03-2018 IPR021401 Protein of unknown function DUF3040 SMALA_RS32485 45d57ba9111c0bd7e7b53fd24eda61b3 162 SMART SM00900 84 159 2.2E-12 T 29-03-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 SMALA_RS32485 45d57ba9111c0bd7e7b53fd24eda61b3 162 Pfam PF04205 FMN-binding domain 86 156 2.9E-9 T 29-03-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 SMALA_RS03550 ca03812b9c90ef1d50d0f1a37eb89d74 362 Pfam PF11199 Protein of unknown function (DUF2891) 32 353 8.5E-125 T 29-03-2018 IPR021365 Protein of unknown function DUF2891 SMALA_RS14430 38e47e36c53eeb67054ed407d290fab5 345 SUPERFAMILY SSF51445 53 316 4.22E-21 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SMALA_RS14430 38e47e36c53eeb67054ed407d290fab5 345 Gene3D G3DSA:3.20.20.80 47 336 2.8E-27 T 29-03-2018 SMALA_RS14430 38e47e36c53eeb67054ed407d290fab5 345 Pfam PF00704 Glycosyl hydrolases family 18 103 312 5.9E-9 T 29-03-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 SMALA_RS07270 b93c52e2e0f46957c429f8f87a786603 107 Pfam PF13459 4Fe-4S single cluster domain 22 92 6.2E-19 T 29-03-2018 SMALA_RS07270 b93c52e2e0f46957c429f8f87a786603 107 Gene3D G3DSA:3.30.70.20 19 94 4.7E-7 T 29-03-2018 SMALA_RS07270 b93c52e2e0f46957c429f8f87a786603 107 PRINTS PR00352 3Fe-4S ferredoxin signature 24 35 1.1E-6 T 29-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 SMALA_RS07270 b93c52e2e0f46957c429f8f87a786603 107 PRINTS PR00352 3Fe-4S ferredoxin signature 78 90 1.1E-6 T 29-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 SMALA_RS07270 b93c52e2e0f46957c429f8f87a786603 107 PRINTS PR00352 3Fe-4S ferredoxin signature 35 45 1.1E-6 T 29-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 SMALA_RS07270 b93c52e2e0f46957c429f8f87a786603 107 SUPERFAMILY SSF54862 22 98 1.98E-9 T 29-03-2018 SMALA_RS11440 28c25d2d2bb662c147bbf5483e8e104c 77 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 9 62 2.5E-9 T 29-03-2018 SMALA_RS11440 28c25d2d2bb662c147bbf5483e8e104c 77 Gene3D G3DSA:3.30.70.20 1 66 1.2E-6 T 29-03-2018 SMALA_RS11440 28c25d2d2bb662c147bbf5483e8e104c 77 SUPERFAMILY SSF54862 5 62 2.37E-10 T 29-03-2018 SMALA_RS11440 28c25d2d2bb662c147bbf5483e8e104c 77 PRINTS PR00352 3Fe-4S ferredoxin signature 20 30 1.4E-6 T 29-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 SMALA_RS11440 28c25d2d2bb662c147bbf5483e8e104c 77 PRINTS PR00352 3Fe-4S ferredoxin signature 49 61 1.4E-6 T 29-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 SMALA_RS11440 28c25d2d2bb662c147bbf5483e8e104c 77 PRINTS PR00352 3Fe-4S ferredoxin signature 9 20 1.4E-6 T 29-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 SMALA_RS15605 b4f62258e86732b244a4f34dfa6c46c5 667 SUPERFAMILY SSF53448 6 243 1.18E-38 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS15605 b4f62258e86732b244a4f34dfa6c46c5 667 Gene3D G3DSA:3.90.550.10 1 282 2.6E-39 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS15605 b4f62258e86732b244a4f34dfa6c46c5 667 Pfam PF00535 Glycosyl transferase family 2 14 146 1.6E-27 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 SMALA_RS06740 a894b5592952eedb255da848c65e4108 217 SUPERFAMILY SSF52058 40 132 2.04E-5 T 29-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like SMALA_RS06740 a894b5592952eedb255da848c65e4108 217 Gene3D G3DSA:3.80.10.10 25 141 3.1E-5 T 29-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like SMALA_RS14665 4722a53c21791592f32399a88e36109a 255 Gene3D G3DSA:3.40.30.10 10 208 7.4E-30 T 29-03-2018 SMALA_RS14665 4722a53c21791592f32399a88e36109a 255 Pfam PF01323 DSBA-like thioredoxin domain 11 203 8.7E-12 T 29-03-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 SMALA_RS14665 4722a53c21791592f32399a88e36109a 255 PIRSF PIRSF006386 3 215 2.6E-42 T 29-03-2018 IPR014440 HCCA isomerase/glutathione S-transferase kappa Reactome: R-HSA-156590 SMALA_RS14665 4722a53c21791592f32399a88e36109a 255 SUPERFAMILY SSF52833 11 207 1.01E-21 T 29-03-2018 IPR012336 Thioredoxin-like fold SMALA_RS32575 9652d3b57465eab9c349a35e7a106d6e 215 SUPERFAMILY SSF55729 7 172 3.67E-35 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS32575 9652d3b57465eab9c349a35e7a106d6e 215 Gene3D G3DSA:3.40.630.30 6 195 3.2E-35 T 29-03-2018 SMALA_RS32575 9652d3b57465eab9c349a35e7a106d6e 215 Pfam PF13302 Acetyltransferase (GNAT) domain 14 154 3.2E-24 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SMALA_RS29495 c514ef34ea098b291f55f898d6ea0e4a 431 SUPERFAMILY SSF53756 10 398 1.57E-80 T 29-03-2018 SMALA_RS29495 c514ef34ea098b291f55f898d6ea0e4a 431 Gene3D G3DSA:3.40.50.2000 10 239 1.4E-30 T 29-03-2018 SMALA_RS29495 c514ef34ea098b291f55f898d6ea0e4a 431 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 233 367 5.6E-16 T 29-03-2018 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 Reactome: R-HSA-156588 SMALA_RS29495 c514ef34ea098b291f55f898d6ea0e4a 431 TIGRFAM TIGR01426 MGT: glycosyltransferase, MGT family 14 398 1.1E-121 T 29-03-2018 IPR006326 UDP-glycosyltransferase, MGT GO:0016758|GO:0016999 SMALA_RS29495 c514ef34ea098b291f55f898d6ea0e4a 431 Gene3D G3DSA:3.40.50.2000 240 383 4.3E-39 T 29-03-2018 SMALA_RS08305 ee5ff23ef94203b53299b8fbd521109c 530 Pfam PF03824 High-affinity nickel-transport protein 253 488 8.4E-15 T 29-03-2018 IPR011541 Nickel/cobalt transporter, high-affinity GO:0015099|GO:0016021|GO:0035444|GO:0046872 SMALA_RS08305 ee5ff23ef94203b53299b8fbd521109c 530 ProSitePatterns PS00018 EF-hand calcium-binding domain. 64 76 - T 29-03-2018 IPR018247 EF-Hand 1, calcium-binding site SMALA_RS10555 406475d1323ded992f28c0ffc98a78e1 579 Gene3D G3DSA:1.20.210.10 29 542 5.5E-198 T 29-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMALA_RS10555 406475d1323ded992f28c0ffc98a78e1 579 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 34 538 7.6E-215 T 29-03-2018 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005507|GO:0005886|GO:0006810|GO:0022900|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 SMALA_RS10555 406475d1323ded992f28c0ffc98a78e1 579 PRINTS PR01165 Cytochrome c oxidase subunit I signature 80 103 4.6E-104 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMALA_RS10555 406475d1323ded992f28c0ffc98a78e1 579 PRINTS PR01165 Cytochrome c oxidase subunit I signature 211 230 4.6E-104 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMALA_RS10555 406475d1323ded992f28c0ffc98a78e1 579 PRINTS PR01165 Cytochrome c oxidase subunit I signature 182 200 4.6E-104 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMALA_RS10555 406475d1323ded992f28c0ffc98a78e1 579 PRINTS PR01165 Cytochrome c oxidase subunit I signature 329 350 4.6E-104 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMALA_RS10555 406475d1323ded992f28c0ffc98a78e1 579 PRINTS PR01165 Cytochrome c oxidase subunit I signature 307 322 4.6E-104 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMALA_RS10555 406475d1323ded992f28c0ffc98a78e1 579 PRINTS PR01165 Cytochrome c oxidase subunit I signature 261 282 4.6E-104 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMALA_RS10555 406475d1323ded992f28c0ffc98a78e1 579 PRINTS PR01165 Cytochrome c oxidase subunit I signature 392 411 4.6E-104 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMALA_RS10555 406475d1323ded992f28c0ffc98a78e1 579 PRINTS PR01165 Cytochrome c oxidase subunit I signature 107 131 4.6E-104 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMALA_RS10555 406475d1323ded992f28c0ffc98a78e1 579 PRINTS PR01165 Cytochrome c oxidase subunit I signature 33 58 4.6E-104 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMALA_RS10555 406475d1323ded992f28c0ffc98a78e1 579 PRINTS PR01165 Cytochrome c oxidase subunit I signature 240 261 4.6E-104 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMALA_RS10555 406475d1323ded992f28c0ffc98a78e1 579 PRINTS PR01165 Cytochrome c oxidase subunit I signature 442 463 4.6E-104 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMALA_RS10555 406475d1323ded992f28c0ffc98a78e1 579 PRINTS PR01165 Cytochrome c oxidase subunit I signature 364 382 4.6E-104 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMALA_RS10555 406475d1323ded992f28c0ffc98a78e1 579 PRINTS PR01165 Cytochrome c oxidase subunit I signature 150 162 4.6E-104 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMALA_RS10555 406475d1323ded992f28c0ffc98a78e1 579 SUPERFAMILY SSF81442 30 541 5.76E-177 T 29-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMALA_RS10555 406475d1323ded992f28c0ffc98a78e1 579 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 43 485 1.3E-146 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMALA_RS10555 406475d1323ded992f28c0ffc98a78e1 579 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 263 317 - T 29-03-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMALA_RS28805 7ef2aa1632081c79f6d9bde71528b545 64 Pfam PF11248 Protein of unknown function (DUF3046) 1 62 1.1E-31 T 29-03-2018 IPR021408 Protein of unknown function DUF3046 SMALA_RS40175 0552e0b6d06f8e9a834800a39fde77b5 378 SUPERFAMILY SSF110296 246 374 1.02E-5 T 29-03-2018 SMALA_RS40175 0552e0b6d06f8e9a834800a39fde77b5 378 Gene3D G3DSA:2.120.10.10 56 376 6.0E-11 T 29-03-2018 SMALA_RS38165 c6e07e8b112208e004492578db0407d2 266 Pfam PF04248 Domain of unknown function (DUF427) 146 239 1.3E-26 T 29-03-2018 IPR007361 Domain of unknown function DUF427 SMALA_RS34570 eceebb902d179696600d105befefde1e 444 SUPERFAMILY SSF103473 2 180 1.44E-46 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS34570 eceebb902d179696600d105befefde1e 444 SUPERFAMILY SSF103473 236 431 1.44E-46 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS34570 eceebb902d179696600d105befefde1e 444 Pfam PF07690 Major Facilitator Superfamily 2 394 1.1E-38 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS34570 eceebb902d179696600d105befefde1e 444 Gene3D G3DSA:1.20.1250.20 1 189 4.8E-21 T 29-03-2018 SMALA_RS34570 eceebb902d179696600d105befefde1e 444 Gene3D G3DSA:1.20.1250.20 241 441 5.6E-16 T 29-03-2018 SMALA_RS34085 814b9aec9f9b6d6af3fdf7a8513925dd 731 SUPERFAMILY SSF82866 477 692 2.22E-23 T 29-03-2018 SMALA_RS34085 814b9aec9f9b6d6af3fdf7a8513925dd 731 Gene3D G3DSA:1.20.1640.10 460 688 2.1E-25 T 29-03-2018 SMALA_RS34085 814b9aec9f9b6d6af3fdf7a8513925dd 731 Gene3D G3DSA:1.20.1640.10 118 333 2.3E-30 T 29-03-2018 SMALA_RS34085 814b9aec9f9b6d6af3fdf7a8513925dd 731 SUPERFAMILY SSF82866 143 330 4.71E-27 T 29-03-2018 SMALA_RS34085 814b9aec9f9b6d6af3fdf7a8513925dd 731 Pfam PF03176 MMPL family 468 695 8.9E-27 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 SMALA_RS34085 814b9aec9f9b6d6af3fdf7a8513925dd 731 Pfam PF03176 MMPL family 45 366 8.8E-49 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 SMALA_RS17380 93640990da2dc4e614f03acdfff4cfdd 240 Gene3D G3DSA:3.40.50.1000 100 233 3.0E-19 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS17380 93640990da2dc4e614f03acdfff4cfdd 240 SUPERFAMILY SSF56784 30 223 6.87E-35 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS17380 93640990da2dc4e614f03acdfff4cfdd 240 Pfam PF13419 Haloacid dehalogenase-like hydrolase 33 193 1.2E-11 T 29-03-2018 IPR023214 HAD-like domain SMALA_RS17380 93640990da2dc4e614f03acdfff4cfdd 240 Gene3D G3DSA:1.10.150.240 42 99 4.2E-5 T 29-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 SMALA_RS37315 58ab04f26c8dcf1b4b89a904f809de45 352 Pfam PF03060 Nitronate monooxygenase 3 336 1.7E-91 T 29-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 SMALA_RS37315 58ab04f26c8dcf1b4b89a904f809de45 352 SUPERFAMILY SSF51412 2 260 2.75E-58 T 29-03-2018 SMALA_RS37315 58ab04f26c8dcf1b4b89a904f809de45 352 Gene3D G3DSA:3.20.20.70 1 349 1.3E-61 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS39745 d92c0150dc707e57b42054723f61fcaa 259 Pfam PF00583 Acetyltransferase (GNAT) family 163 247 8.9E-7 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SMALA_RS39745 d92c0150dc707e57b42054723f61fcaa 259 SUPERFAMILY SSF55729 26 252 1.74E-19 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS39745 d92c0150dc707e57b42054723f61fcaa 259 Gene3D G3DSA:3.40.630.30 91 254 1.2E-18 T 29-03-2018 SMALA_RS33610 b31e0b5008252a0430bc4643c33314ab 267 Pfam PF02811 PHP domain 3 118 3.7E-13 T 29-03-2018 IPR004013 PHP domain GO:0003824 SMALA_RS33610 b31e0b5008252a0430bc4643c33314ab 267 SUPERFAMILY SSF89550 1 265 2.22E-47 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 SMALA_RS33610 b31e0b5008252a0430bc4643c33314ab 267 Gene3D G3DSA:3.20.20.140 1 264 1.1E-40 T 29-03-2018 SMALA_RS33610 b31e0b5008252a0430bc4643c33314ab 267 TIGRFAM TIGR01856 hisJ_fam: histidinol phosphate phosphatase, HisJ family 2 242 2.0E-46 T 29-03-2018 IPR010140 Histidinol phosphate phosphatase, HisJ GO:0000105|GO:0004401 KEGG: 00340+3.1.3.15 SMALA_RS01300 95eef18130d83429be031c3ddc47870c 375 Gene3D G3DSA:3.20.20.70 2 373 6.4E-107 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS01300 95eef18130d83429be031c3ddc47870c 375 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 13 344 4.3E-66 T 29-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 SMALA_RS01300 95eef18130d83429be031c3ddc47870c 375 SUPERFAMILY SSF51395 12 371 1.37E-102 T 29-03-2018 SMALA_RS08295 378f9b08dc487ec76870043f87813fb8 504 Pfam PF14224 Domain of unknown function (DUF4331) 37 437 1.4E-159 T 29-03-2018 IPR025566 Protein of unknown function DUF4331 SMALA_RS08295 378f9b08dc487ec76870043f87813fb8 504 Gene3D G3DSA:1.20.5.100 458 500 8.5E-4 T 29-03-2018 SMALA_RS01020 5451f6c990e207e04a7a4f783640ba52 257 Pfam PF09490 Probable cobalt transporter subunit (CbtA) 7 229 9.4E-69 T 29-03-2018 IPR012666 Cobalt transporter subunit CbtA, putative SMALA_RS28870 e4f5df852c5a9040b9d7e306f6b1e65c 200 SUPERFAMILY SSF53335 8 177 4.18E-32 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS28870 e4f5df852c5a9040b9d7e306f6b1e65c 200 Pfam PF08241 Methyltransferase domain 31 121 1.1E-16 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 SMALA_RS28870 e4f5df852c5a9040b9d7e306f6b1e65c 200 Gene3D G3DSA:3.40.50.150 1 179 8.4E-28 T 29-03-2018 SMALA_RS23900 bbea6a191ebd1fc736ac1f9cbcf0694e 125 SUPERFAMILY SSF54909 34 112 2.49E-11 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel SMALA_RS23900 bbea6a191ebd1fc736ac1f9cbcf0694e 125 Gene3D G3DSA:3.30.70.100 1 123 3.3E-37 T 29-03-2018 SMALA_RS23900 bbea6a191ebd1fc736ac1f9cbcf0694e 125 Pfam PF07045 Domain of unknown function (DUF1330) 35 110 4.0E-7 T 29-03-2018 IPR010753 Domain of unknown function DUF1330 SMALA_RS02810 b8b6855e27d2308e54f138c1af927b14 251 Gene3D G3DSA:3.40.50.1820 1 249 8.2E-34 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS02810 b8b6855e27d2308e54f138c1af927b14 251 SUPERFAMILY SSF53474 7 251 5.94E-43 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS02810 b8b6855e27d2308e54f138c1af927b14 251 Pfam PF01738 Dienelactone hydrolase family 19 250 1.4E-47 T 29-03-2018 IPR002925 Dienelactone hydrolase GO:0016787 SMALA_RS37565 6dc48b4100b873a524d14f309919ecc6 162 Pfam PF00583 Acetyltransferase (GNAT) family 30 135 4.4E-16 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SMALA_RS37565 6dc48b4100b873a524d14f309919ecc6 162 SUPERFAMILY SSF55729 1 161 1.11E-30 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS37565 6dc48b4100b873a524d14f309919ecc6 162 Gene3D G3DSA:3.40.630.30 1 162 3.6E-35 T 29-03-2018 SMALA_RS24630 2f1c0111a68a37da7a5ec6c504384e13 295 Pfam PF00482 Type II secretion system (T2SS), protein F 152 278 4.1E-22 T 29-03-2018 IPR018076 Type II secretion system F domain SMALA_RS04685 3a3baf21e5feebafc4eb84cccd665ef1 275 SUPERFAMILY SSF52317 52 269 1.97E-47 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS04685 3a3baf21e5feebafc4eb84cccd665ef1 275 Gene3D G3DSA:3.40.50.880 44 274 7.4E-63 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS04685 3a3baf21e5feebafc4eb84cccd665ef1 275 Pfam PF06283 Trehalose utilisation 52 265 6.9E-83 T 29-03-2018 IPR029010 ThuA-like domain SMALA_RS07965 10eca525a156f267b8000d0291270344 235 Gene3D G3DSA:3.40.50.720 1 141 4.5E-37 T 29-03-2018 SMALA_RS07965 10eca525a156f267b8000d0291270344 235 Gene3D G3DSA:3.40.50.720 142 233 4.0E-12 T 29-03-2018 SMALA_RS07965 10eca525a156f267b8000d0291270344 235 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 2.3E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS07965 10eca525a156f267b8000d0291270344 235 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 71 82 2.3E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS07965 10eca525a156f267b8000d0291270344 235 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 2.3E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS07965 10eca525a156f267b8000d0291270344 235 SUPERFAMILY SSF51735 3 231 1.12E-48 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS07965 10eca525a156f267b8000d0291270344 235 Pfam PF00106 short chain dehydrogenase 3 200 1.6E-34 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS07965 10eca525a156f267b8000d0291270344 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 5.8E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS07965 10eca525a156f267b8000d0291270344 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 5.8E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS07965 10eca525a156f267b8000d0291270344 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 5.8E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS07965 10eca525a156f267b8000d0291270344 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 5.8E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS07965 10eca525a156f267b8000d0291270344 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 71 82 5.8E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS23335 eed6bbaed904d90d227b7765b491dfc7 338 TIGRFAM TIGR02778 ligD_pol: DNA ligase D, polymerase domain 12 256 1.1E-77 T 29-03-2018 IPR014145 DNA ligase D, polymerase domain SMALA_RS07110 f1d6d309d887d98657ee6e50ef4b15da 233 Gene3D G3DSA:3.40.50.970 28 231 5.0E-38 T 29-03-2018 SMALA_RS07110 f1d6d309d887d98657ee6e50ef4b15da 233 SUPERFAMILY SSF52518 32 227 4.77E-46 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold SMALA_RS07110 f1d6d309d887d98657ee6e50ef4b15da 233 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 28 223 5.0E-26 T 29-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SMALA_RS24275 32351860858bb54e0cf3484fc473e250 286 Pfam PF13649 Methyltransferase domain 54 150 1.8E-17 T 29-03-2018 SMALA_RS24275 32351860858bb54e0cf3484fc473e250 286 Gene3D G3DSA:3.40.50.150 2 259 3.0E-31 T 29-03-2018 SMALA_RS24275 32351860858bb54e0cf3484fc473e250 286 SUPERFAMILY SSF53335 27 233 2.3E-33 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS29460 599399bd1d336920abd74a7997f6ca8b 238 Gene3D G3DSA:3.40.30.10 8 207 6.4E-32 T 29-03-2018 SMALA_RS29460 599399bd1d336920abd74a7997f6ca8b 238 PIRSF PIRSF006386 3 213 6.2E-42 T 29-03-2018 IPR014440 HCCA isomerase/glutathione S-transferase kappa Reactome: R-HSA-156590 SMALA_RS29460 599399bd1d336920abd74a7997f6ca8b 238 Pfam PF01323 DSBA-like thioredoxin domain 11 201 3.8E-18 T 29-03-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 SMALA_RS29460 599399bd1d336920abd74a7997f6ca8b 238 SUPERFAMILY SSF52833 10 204 1.6E-27 T 29-03-2018 IPR012336 Thioredoxin-like fold SMALA_RS16460 3ccd1cc26672e145296021193bb96165 191 Pfam PF04892 VanZ like family 22 141 9.9E-11 T 29-03-2018 IPR006976 VanZ-like SMALA_RS10790 3b89c08d5d864f184f5afd84087b1e88 129 Pfam PF12973 ChrR Cupin-like domain 24 114 6.6E-11 T 29-03-2018 IPR025979 ChrR-like cupin domain SMALA_RS10790 3b89c08d5d864f184f5afd84087b1e88 129 SUPERFAMILY SSF51182 14 117 3.96E-18 T 29-03-2018 IPR011051 RmlC-like cupin domain SMALA_RS10790 3b89c08d5d864f184f5afd84087b1e88 129 Gene3D G3DSA:2.60.120.10 4 119 2.6E-15 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SMALA_RS38470 97439c8521d18fc533eede9f87060c36 87 SUPERFAMILY SSF47336 5 83 1.1E-9 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS38470 97439c8521d18fc533eede9f87060c36 87 Pfam PF00550 Phosphopantetheine attachment site 26 77 3.2E-4 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS38470 97439c8521d18fc533eede9f87060c36 87 Gene3D G3DSA:1.10.1200.10 1 84 2.0E-10 T 29-03-2018 SMALA_RS30435 0660045a2dec680361b44fe576cf4d0d 293 Gene3D G3DSA:1.25.40.10 47 255 2.3E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS38535 471b579b0c53dfb17a690eabb212ee20 179 Pfam PF08714 Formaldehyde-activating enzyme (Fae) 11 163 4.6E-51 T 29-03-2018 IPR014826 Formaldehyde-activating enzyme GO:0016051|GO:0016840 KEGG: 00030+4.1.2.43|KEGG: 00680+4.2.1.147+4.1.2.43|MetaCyc: PWY-1723|MetaCyc: PWY-1861|MetaCyc: PWY-7796 SMALA_RS38535 471b579b0c53dfb17a690eabb212ee20 179 Gene3D G3DSA:3.30.230.60 9 170 1.4E-53 T 29-03-2018 IPR014826 Formaldehyde-activating enzyme GO:0016051|GO:0016840 KEGG: 00030+4.1.2.43|KEGG: 00680+4.2.1.147+4.1.2.43|MetaCyc: PWY-1723|MetaCyc: PWY-1861|MetaCyc: PWY-7796 SMALA_RS38535 471b579b0c53dfb17a690eabb212ee20 179 SUPERFAMILY SSF54211 9 162 1.21E-44 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SMALA_RS38535 471b579b0c53dfb17a690eabb212ee20 179 TIGRFAM TIGR03126 one_C_fae: formaldehyde-activating enzyme 10 163 7.2E-39 T 29-03-2018 IPR014826 Formaldehyde-activating enzyme GO:0016051|GO:0016840 KEGG: 00030+4.1.2.43|KEGG: 00680+4.2.1.147+4.1.2.43|MetaCyc: PWY-1723|MetaCyc: PWY-1861|MetaCyc: PWY-7796 SMALA_RS31160 85d6383e0a8adf6adb10a3532762ebf2 406 Pfam PF13407 Periplasmic binding protein domain 82 338 1.5E-58 T 29-03-2018 IPR025997 Periplasmic binding protein SMALA_RS31160 85d6383e0a8adf6adb10a3532762ebf2 406 Gene3D G3DSA:3.40.50.2300 184 385 8.7E-32 T 29-03-2018 SMALA_RS31160 85d6383e0a8adf6adb10a3532762ebf2 406 Gene3D G3DSA:3.40.50.2300 25 183 1.3E-13 T 29-03-2018 SMALA_RS31160 85d6383e0a8adf6adb10a3532762ebf2 406 SUPERFAMILY SSF53822 91 374 4.32E-56 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SMALA_RS14220 1aca58be3c9492a7a393142dd591f4c0 302 Pfam PF14472 Domain of unknown function (DUF4429) 139 225 3.0E-19 T 29-03-2018 IPR027860 Domain of unknown function DUF4429 SMALA_RS14220 1aca58be3c9492a7a393142dd591f4c0 302 Pfam PF14472 Domain of unknown function (DUF4429) 11 105 4.9E-21 T 29-03-2018 IPR027860 Domain of unknown function DUF4429 SMALA_RS14220 1aca58be3c9492a7a393142dd591f4c0 302 Pfam PF09851 Short C-terminal domain 270 296 1.6E-6 T 29-03-2018 IPR018649 SHOCT domain SMALA_RS09870 3a7e089f8104d4063b5960d9331192ff 533 Gene3D G3DSA:3.90.1150.10 416 532 1.1E-17 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SMALA_RS09870 3a7e089f8104d4063b5960d9331192ff 533 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 244 471 1.7E-33 T 29-03-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 SMALA_RS09870 3a7e089f8104d4063b5960d9331192ff 533 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 65 179 2.5E-5 T 29-03-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 SMALA_RS09870 3a7e089f8104d4063b5960d9331192ff 533 Gene3D G3DSA:3.40.640.10 118 415 1.4E-48 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMALA_RS09870 3a7e089f8104d4063b5960d9331192ff 533 SUPERFAMILY SSF53383 25 174 2.08E-86 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS09870 3a7e089f8104d4063b5960d9331192ff 533 SUPERFAMILY SSF53383 229 527 2.08E-86 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SMALA_RS14750 7382c44c4981d4af5eaf1dc89e72e7ea 83 Gene3D G3DSA:1.10.1200.10 4 82 1.8E-13 T 29-03-2018 SMALA_RS14750 7382c44c4981d4af5eaf1dc89e72e7ea 83 SUPERFAMILY SSF47336 6 80 6.54E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS14750 7382c44c4981d4af5eaf1dc89e72e7ea 83 Pfam PF00550 Phosphopantetheine attachment site 11 75 3.8E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SMALA_RS40195 7cc08df4404d0eec9aecdc9e7670b938 235 Pfam PF08445 FR47-like protein 143 226 3.2E-24 T 29-03-2018 IPR013653 FR47-like GO:0016747 SMALA_RS40195 7cc08df4404d0eec9aecdc9e7670b938 235 SUPERFAMILY SSF55729 112 226 5.14E-21 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS40195 7cc08df4404d0eec9aecdc9e7670b938 235 Gene3D G3DSA:3.40.630.30 42 230 1.5E-22 T 29-03-2018 SMALA_RS01440 93c1116e7e6b22a63bde50f041af4bde 780 Gene3D G3DSA:3.40.50.300 179 579 1.0E-31 T 29-03-2018 SMALA_RS01440 93c1116e7e6b22a63bde50f041af4bde 780 Pfam PF13245 AAA domain 185 566 1.3E-11 T 29-03-2018 SMALA_RS01440 93c1116e7e6b22a63bde50f041af4bde 780 SUPERFAMILY SSF52540 515 733 6.69E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS01440 93c1116e7e6b22a63bde50f041af4bde 780 SUPERFAMILY SSF52540 173 252 6.69E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS01440 93c1116e7e6b22a63bde50f041af4bde 780 Gene3D G3DSA:3.40.50.300 592 747 5.0E-14 T 29-03-2018 SMALA_RS02070 4d9ce182ee657a8348dfcbf0eb04097c 210 Pfam PF03734 L,D-transpeptidase catalytic domain 82 201 6.4E-6 T 29-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 SMALA_RS02070 4d9ce182ee657a8348dfcbf0eb04097c 210 Gene3D G3DSA:2.40.440.10 32 202 2.8E-4 T 29-03-2018 SMALA_RS17210 f8b8b852292949fe43e15253225ea507 527 Gene3D G3DSA:3.40.50.980 14 183 1.5E-39 T 29-03-2018 SMALA_RS17210 f8b8b852292949fe43e15253225ea507 527 Pfam PF13193 AMP-binding enzyme C-terminal domain 437 511 1.4E-17 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SMALA_RS17210 f8b8b852292949fe43e15253225ea507 527 Gene3D G3DSA:2.30.38.10 337 420 2.4E-29 T 29-03-2018 SMALA_RS17210 f8b8b852292949fe43e15253225ea507 527 Gene3D G3DSA:3.30.300.30 421 527 8.6E-28 T 29-03-2018 SMALA_RS17210 f8b8b852292949fe43e15253225ea507 527 Gene3D G3DSA:3.40.50.980 184 336 4.9E-49 T 29-03-2018 SMALA_RS17210 f8b8b852292949fe43e15253225ea507 527 ProSitePatterns PS00455 Putative AMP-binding domain signature. 178 189 - T 29-03-2018 IPR020845 AMP-binding, conserved site SMALA_RS17210 f8b8b852292949fe43e15253225ea507 527 Pfam PF00501 AMP-binding enzyme 23 427 2.3E-108 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMALA_RS17210 f8b8b852292949fe43e15253225ea507 527 SUPERFAMILY SSF56801 19 522 5.36E-154 T 29-03-2018 SMALA_RS21165 6fa24dd2a36a65744ad3f0ef722aec9c 331 Pfam PF14390 Putative PD-(D/E)XK family member, (DUF4420) 64 311 3.5E-36 T 29-03-2018 IPR025534 Putative PD-(D/E)XK family member (DUF4420) SMALA_RS01790 026c24d2be5f79b4798904b1e5dbb55a 214 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 65 8.6E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS01790 026c24d2be5f79b4798904b1e5dbb55a 214 Gene3D G3DSA:1.10.357.10 1 214 3.2E-32 T 29-03-2018 SMALA_RS01790 026c24d2be5f79b4798904b1e5dbb55a 214 SUPERFAMILY SSF46689 6 86 1.49E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS38160 1eb7047118e7358db8ac9200062498f7 424 Pfam PF04932 O-Antigen ligase 208 338 1.5E-10 T 29-03-2018 IPR007016 O-antigen ligase-related SMALA_RS20220 d50f9485db39cc987ecdfeceb7094c37 142 Pfam PF03259 Roadblock/LC7 domain 8 101 7.3E-24 T 29-03-2018 IPR004942 Roadblock/LAMTOR2 domain SMALA_RS20220 d50f9485db39cc987ecdfeceb7094c37 142 SMART SM00960 9 101 5.6E-27 T 29-03-2018 IPR004942 Roadblock/LAMTOR2 domain SMALA_RS20220 d50f9485db39cc987ecdfeceb7094c37 142 SUPERFAMILY SSF103196 2 130 2.62E-34 T 29-03-2018 SMALA_RS20220 d50f9485db39cc987ecdfeceb7094c37 142 Gene3D G3DSA:3.30.450.30 4 133 1.7E-38 T 29-03-2018 SMALA_RS20745 732b92dbe8569f50eae94357fa740a74 179 Gene3D G3DSA:3.40.50.2020 1 179 1.1E-28 T 29-03-2018 SMALA_RS20745 732b92dbe8569f50eae94357fa740a74 179 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 13 172 2.9E-35 T 29-03-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 SMALA_RS20745 732b92dbe8569f50eae94357fa740a74 179 SUPERFAMILY SSF53271 5 175 2.1E-34 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like SMALA_RS20745 732b92dbe8569f50eae94357fa740a74 179 Pfam PF00156 Phosphoribosyl transferase domain 72 159 2.0E-10 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 SMALA_RS20745 732b92dbe8569f50eae94357fa740a74 179 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 179 24.356 T 29-03-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 SMALA_RS41665 71043f56e246ef5e716efe986dbc535f 290 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 99 284 8.4E-24 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS41665 71043f56e246ef5e716efe986dbc535f 290 SUPERFAMILY SSF161098 21 290 2.71E-70 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS41665 71043f56e246ef5e716efe986dbc535f 290 Gene3D G3DSA:1.10.3720.10 13 278 2.4E-45 T 29-03-2018 SMALA_RS16100 0dcf2ab63a9c0e7f3adecd42aa89f742 312 SUPERFAMILY SSF53850 46 310 2.35E-53 T 29-03-2018 SMALA_RS16100 0dcf2ab63a9c0e7f3adecd42aa89f742 312 Gene3D G3DSA:3.40.190.10 178 310 5.3E-19 T 29-03-2018 SMALA_RS16100 0dcf2ab63a9c0e7f3adecd42aa89f742 312 Gene3D G3DSA:3.40.190.10 35 177 2.0E-27 T 29-03-2018 SMALA_RS16100 0dcf2ab63a9c0e7f3adecd42aa89f742 312 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 47 305 2.7E-51 T 29-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 SMALA_RS14330 502dc407b3659047ad5fedb84ec3e8ca 322 SUPERFAMILY SSF63829 38 304 4.9E-25 T 29-03-2018 SMALA_RS14330 502dc407b3659047ad5fedb84ec3e8ca 322 Gene3D G3DSA:2.120.10.30 35 315 8.0E-24 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like SMALA_RS31865 87eeda2a3d8954b8c226a88fbf7cff16 1122 Gene3D G3DSA:1.25.10.10 45 1120 3.4E-9 T 29-03-2018 IPR011989 Armadillo-like helical SMALA_RS26275 ab331645d77be340a381e5b4348b22f6 186 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 58 7.4E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS26275 ab331645d77be340a381e5b4348b22f6 186 SUPERFAMILY SSF46689 6 76 8.72E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS26275 ab331645d77be340a381e5b4348b22f6 186 Gene3D G3DSA:1.10.357.10 3 184 5.3E-18 T 29-03-2018 SMALA_RS42840 764a4a243bb2434da2dcedaead29f113 387 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 92 310 9.7E-27 T 29-03-2018 IPR018713 Domain of unknown function DUF2236 SMALA_RS41070 57c39499e03dbf4621d64117ca8d3585 356 Gene3D G3DSA:3.20.20.100 30 346 6.9E-87 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS41070 57c39499e03dbf4621d64117ca8d3585 356 SUPERFAMILY SSF51430 29 342 3.67E-89 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS41070 57c39499e03dbf4621d64117ca8d3585 356 Pfam PF00248 Aldo/keto reductase family 42 341 2.3E-66 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS39670 57bc1cde502a5a87776246e063c6e047 311 SUPERFAMILY SSF161098 91 292 3.6E-14 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS39670 57bc1cde502a5a87776246e063c6e047 311 Gene3D G3DSA:1.10.3720.10 3 293 3.2E-31 T 29-03-2018 SMALA_RS39670 57bc1cde502a5a87776246e063c6e047 311 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 304 2.8E-33 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS10685 dfb4a8f937d68d5b4ad0320072cdc77a 172 Pfam PF14024 Protein of unknown function (DUF4240) 1 128 1.1E-44 T 29-03-2018 IPR025334 Domain of unknown function (DUF4240 SMALA_RS04015 4ddaa9bfdb3d5c0ec44ebadb9fa4d53d 325 Pfam PF00480 ROK family 7 307 4.2E-57 T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 SMALA_RS04015 4ddaa9bfdb3d5c0ec44ebadb9fa4d53d 325 ProSitePatterns PS01125 ROK family signature. 138 165 - T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 SMALA_RS04015 4ddaa9bfdb3d5c0ec44ebadb9fa4d53d 325 Gene3D G3DSA:3.30.420.40 2 123 3.0E-24 T 29-03-2018 SMALA_RS04015 4ddaa9bfdb3d5c0ec44ebadb9fa4d53d 325 SUPERFAMILY SSF53067 6 308 4.03E-58 T 29-03-2018 SMALA_RS04015 4ddaa9bfdb3d5c0ec44ebadb9fa4d53d 325 Gene3D G3DSA:3.30.420.40 124 318 3.2E-51 T 29-03-2018 SMALA_RS17335 44ace03329b4ca9d977fca4be04e095f 1147 Gene3D G3DSA:3.30.565.10 43 261 2.8E-11 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS17335 44ace03329b4ca9d977fca4be04e095f 1147 SUPERFAMILY SSF55874 48 143 3.26E-9 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS03835 77fd60c8ad4341d1c9cc3cdbde3cac8f 264 Gene3D G3DSA:3.40.50.1860 110 229 1.2E-21 T 29-03-2018 SMALA_RS03835 77fd60c8ad4341d1c9cc3cdbde3cac8f 264 SUPERFAMILY SSF53681 106 240 1.33E-18 T 29-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMALA_RS03835 77fd60c8ad4341d1c9cc3cdbde3cac8f 264 Gene3D G3DSA:3.40.50.1860 11 109 2.0E-18 T 29-03-2018 SMALA_RS03835 77fd60c8ad4341d1c9cc3cdbde3cac8f 264 Pfam PF01177 Asp/Glu/Hydantoin racemase 28 194 4.6E-13 T 29-03-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMALA_RS03835 77fd60c8ad4341d1c9cc3cdbde3cac8f 264 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 67 75 - T 29-03-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMALA_RS03835 77fd60c8ad4341d1c9cc3cdbde3cac8f 264 SUPERFAMILY SSF53681 2 102 1.24E-21 T 29-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMALA_RS19520 dc71e5485e4f0182671ae57735f11768 159 Gene3D G3DSA:1.10.10.10 23 154 6.1E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS19520 dc71e5485e4f0182671ae57735f11768 159 SUPERFAMILY SSF46785 19 137 2.06E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS19520 dc71e5485e4f0182671ae57735f11768 159 PRINTS PR00598 Bacterial regulatory protein MarR family signature 67 83 2.1E-5 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS19520 dc71e5485e4f0182671ae57735f11768 159 PRINTS PR00598 Bacterial regulatory protein MarR family signature 84 99 2.1E-5 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS19520 dc71e5485e4f0182671ae57735f11768 159 PRINTS PR00598 Bacterial regulatory protein MarR family signature 103 119 2.1E-5 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS19520 dc71e5485e4f0182671ae57735f11768 159 Pfam PF01047 MarR family 65 107 1.6E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS19520 dc71e5485e4f0182671ae57735f11768 159 SMART SM00347 38 143 2.0E-13 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS07805 d222246fe234792d192dd64ab81e9a85 260 Gene3D G3DSA:3.40.50.150 1 233 1.8E-25 T 29-03-2018 SMALA_RS07805 d222246fe234792d192dd64ab81e9a85 260 SUPERFAMILY SSF53335 4 196 5.31E-27 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS07805 d222246fe234792d192dd64ab81e9a85 260 Pfam PF08241 Methyltransferase domain 44 141 8.3E-13 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 SMALA_RS38830 11cfc4b2a5435d5704e81b912b2d7b6c 341 Gene3D G3DSA:1.10.3470.10 1 338 4.6E-74 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SMALA_RS38830 11cfc4b2a5435d5704e81b912b2d7b6c 341 Pfam PF01032 FecCD transport family 9 330 2.8E-92 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 SMALA_RS38830 11cfc4b2a5435d5704e81b912b2d7b6c 341 SUPERFAMILY SSF81345 2 330 1.44E-79 T 29-03-2018 IPR029022 ABC transporter, BtuC-like SMALA_RS11120 396050b48c212471587ee58151393a4e 377 Pfam PF13473 Cupredoxin-like domain 16 116 8.6E-13 T 29-03-2018 IPR028096 EfeO-type cupredoxin-like domain SMALA_RS11120 396050b48c212471587ee58151393a4e 377 Pfam PF09375 Imelysin 139 369 4.6E-40 T 29-03-2018 IPR018976 Peptidase M75, Imelysin SMALA_RS06835 6609bf644eb263f52c32fc60b7485b00 358 Gene3D G3DSA:3.30.420.40 152 333 2.4E-41 T 29-03-2018 SMALA_RS06835 6609bf644eb263f52c32fc60b7485b00 358 Pfam PF00480 ROK family 33 323 8.7E-38 T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 SMALA_RS06835 6609bf644eb263f52c32fc60b7485b00 358 SUPERFAMILY SSF53067 32 325 9.18E-43 T 29-03-2018 SMALA_RS06835 6609bf644eb263f52c32fc60b7485b00 358 Gene3D G3DSA:3.30.420.40 23 151 2.4E-15 T 29-03-2018 SMALA_RS17460 f835f430de58e33e23d62e03261a6df6 448 Pfam PF00999 Sodium/hydrogen exchanger family 15 373 1.2E-60 T 29-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 SMALA_RS17460 f835f430de58e33e23d62e03261a6df6 448 Gene3D G3DSA:1.20.91.10 230 318 1.8E-6 T 29-03-2018 SMALA_RS05880 3578d57c0ce14f14d8e18dc57feab7f8 293 Gene3D G3DSA:3.40.50.720 1 291 8.5E-31 T 29-03-2018 SMALA_RS05880 3578d57c0ce14f14d8e18dc57feab7f8 293 SUPERFAMILY SSF51735 1 282 3.53E-36 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS05880 3578d57c0ce14f14d8e18dc57feab7f8 293 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 82 4.4E-11 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 SMALA_RS13660 4d0dd85d841aac9694ddf5de2b00bd7f 251 Pfam PF01061 ABC-2 type transporter 2 210 5.9E-15 T 29-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 SMALA_RS13660 4d0dd85d841aac9694ddf5de2b00bd7f 251 PIRSF PIRSF006648 1 250 8.7E-24 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMALA_RS00680 ac6a9d9f6361e55068bd3982baa50610 168 SUPERFAMILY SSF109854 5 165 2.75E-32 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes SMALA_RS00680 ac6a9d9f6361e55068bd3982baa50610 168 Pfam PF04978 Protein of unknown function (DUF664) 7 165 3.0E-22 T 29-03-2018 IPR007061 Protein of unknown function DUF664 SMALA_RS00680 ac6a9d9f6361e55068bd3982baa50610 168 Gene3D G3DSA:1.20.120.450 1 168 3.8E-33 T 29-03-2018 SMALA_RS12565 07b4d51713b3e99bba5488aff49c02ae 311 Gene3D G3DSA:1.20.58.370 8 51 2.8E-4 T 29-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain SMALA_RS12565 07b4d51713b3e99bba5488aff49c02ae 311 SUPERFAMILY SSF161098 64 298 1.01E-44 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS12565 07b4d51713b3e99bba5488aff49c02ae 311 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 97 299 4.3E-10 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS12565 07b4d51713b3e99bba5488aff49c02ae 311 Gene3D G3DSA:1.10.3720.10 71 305 4.7E-37 T 29-03-2018 SMALA_RS37740 18cf37a930aa95ed53eb65745cb96e27 233 Gene3D G3DSA:2.40.50.260 9 119 1.6E-28 T 29-03-2018 SMALA_RS37740 18cf37a930aa95ed53eb65745cb96e27 233 SUPERFAMILY SSF69255 15 92 3.66E-20 T 29-03-2018 SMALA_RS24140 6afb4f893447aa2c2196f1b09703a1d4 122 Pfam PF00741 Gas vesicle protein 21 57 1.8E-15 T 29-03-2018 IPR000638 Gas vesicle protein GvpA GO:0005198|GO:0012506 SMALA_RS24140 6afb4f893447aa2c2196f1b09703a1d4 122 ProSitePatterns PS00234 Gas vesicles protein GVPa signature 1. 21 35 - T 29-03-2018 IPR018493 Gas vesicle protein GvpA, conserved site GO:0005198|GO:0012506 SMALA_RS42110 8bdf91b6729346f6d7cf732b9d8759e3 443 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 159 177 2.2E-7 T 29-03-2018 SMALA_RS42110 8bdf91b6729346f6d7cf732b9d8759e3 443 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 14 33 2.2E-7 T 29-03-2018 SMALA_RS42110 8bdf91b6729346f6d7cf732b9d8759e3 443 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 201 219 2.2E-7 T 29-03-2018 SMALA_RS42110 8bdf91b6729346f6d7cf732b9d8759e3 443 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 13 35 1.3E-5 T 29-03-2018 SMALA_RS42110 8bdf91b6729346f6d7cf732b9d8759e3 443 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 201 226 1.3E-5 T 29-03-2018 SMALA_RS42110 8bdf91b6729346f6d7cf732b9d8759e3 443 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 162 171 1.3E-5 T 29-03-2018 SMALA_RS42110 8bdf91b6729346f6d7cf732b9d8759e3 443 Gene3D G3DSA:3.50.50.60 9 199 9.5E-18 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS42110 8bdf91b6729346f6d7cf732b9d8759e3 443 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 11 348 1.8E-108 T 29-03-2018 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase SMALA_RS42110 8bdf91b6729346f6d7cf732b9d8759e3 443 SUPERFAMILY SSF51905 11 247 3.95E-22 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS42110 8bdf91b6729346f6d7cf732b9d8759e3 443 Gene3D G3DSA:3.50.50.60 200 432 2.0E-16 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS42110 8bdf91b6729346f6d7cf732b9d8759e3 443 SUPERFAMILY SSF51905 202 420 1.8E-13 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS40535 a88a61cae017f96e0025d1631fd2be32 254 SUPERFAMILY SSF161098 53 237 1.7E-31 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS40535 a88a61cae017f96e0025d1631fd2be32 254 Gene3D G3DSA:1.10.3720.10 7 252 2.8E-29 T 29-03-2018 SMALA_RS40535 a88a61cae017f96e0025d1631fd2be32 254 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 73 249 2.6E-30 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS17010 4a4f0985585601abebfbfecea38746c3 172 Pfam PF07681 DoxX 23 125 4.0E-20 T 29-03-2018 IPR032808 DoxX family SMALA_RS06240 97e7d7d985fca80575e847cbedaf22f0 321 Pfam PF01032 FecCD transport family 2 316 9.5E-96 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 SMALA_RS06240 97e7d7d985fca80575e847cbedaf22f0 321 SUPERFAMILY SSF81345 2 317 1.31E-83 T 29-03-2018 IPR029022 ABC transporter, BtuC-like SMALA_RS06240 97e7d7d985fca80575e847cbedaf22f0 321 Gene3D G3DSA:1.10.3470.10 1 320 3.4E-78 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SMALA_RS25925 c8697aefc90120e13969c38d8b9a48fa 96 Pfam PF11305 Protein of unknown function (DUF3107) 22 94 3.1E-29 T 29-03-2018 IPR021456 Protein of unknown function DUF3107 SMALA_RS04490 a277b659db1dd26b23d70f820eb079e3 344 Gene3D G3DSA:2.130.10.10 1 127 9.3E-8 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMALA_RS04490 a277b659db1dd26b23d70f820eb079e3 344 Gene3D G3DSA:2.130.10.10 281 343 2.7E-6 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMALA_RS04490 a277b659db1dd26b23d70f820eb079e3 344 Gene3D G3DSA:2.130.10.10 128 280 2.9E-26 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMALA_RS04490 a277b659db1dd26b23d70f820eb079e3 344 SUPERFAMILY SSF51004 15 329 2.09E-41 T 29-03-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain SMALA_RS04490 a277b659db1dd26b23d70f820eb079e3 344 Pfam PF10282 Lactonase, 7-bladed beta-propeller 10 343 2.8E-97 T 29-03-2018 IPR019405 Lactonase, 7-bladed beta propeller SMALA_RS31130 62d0ecb40734bbf181dd7d8f7a482412 341 SUPERFAMILY SSF51556 4 337 1.47E-74 T 29-03-2018 IPR032466 Metal-dependent hydrolase SMALA_RS31130 62d0ecb40734bbf181dd7d8f7a482412 341 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 5 334 1.3E-79 T 29-03-2018 IPR008257 Renal dipeptidase family GO:0006508|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 SMALA_RS31130 62d0ecb40734bbf181dd7d8f7a482412 341 Gene3D G3DSA:3.20.20.140 243 337 2.7E-21 T 29-03-2018 SMALA_RS31130 62d0ecb40734bbf181dd7d8f7a482412 341 Gene3D G3DSA:3.20.20.140 1 242 1.6E-64 T 29-03-2018 SMALA_RS06130 aca019e644d80642588ae067b8b20cab 549 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 182 197 4.3E-40 T 29-03-2018 SMALA_RS06130 aca019e644d80642588ae067b8b20cab 549 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 305 320 4.3E-40 T 29-03-2018 SMALA_RS06130 aca019e644d80642588ae067b8b20cab 549 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 320 336 4.3E-40 T 29-03-2018 SMALA_RS06130 aca019e644d80642588ae067b8b20cab 549 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 13 35 4.3E-40 T 29-03-2018 SMALA_RS06130 aca019e644d80642588ae067b8b20cab 549 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 338 356 4.3E-40 T 29-03-2018 SMALA_RS06130 aca019e644d80642588ae067b8b20cab 549 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 356 372 4.3E-40 T 29-03-2018 SMALA_RS06130 aca019e644d80642588ae067b8b20cab 549 SUPERFAMILY SSF51905 292 370 3.03E-55 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS06130 aca019e644d80642588ae067b8b20cab 549 SUPERFAMILY SSF51905 13 203 3.03E-55 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS06130 aca019e644d80642588ae067b8b20cab 549 Pfam PF01494 FAD binding domain 12 368 3.8E-75 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 SMALA_RS06130 aca019e644d80642588ae067b8b20cab 549 Gene3D G3DSA:3.50.50.60 10 415 5.1E-58 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS29720 f227278c3abbf4132f25a8f85e22b5af 188 SUPERFAMILY SSF52980 27 175 3.22E-17 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 SMALA_RS29720 f227278c3abbf4132f25a8f85e22b5af 188 Gene3D G3DSA:3.90.1570.10 11 188 4.2E-27 T 29-03-2018 SMALA_RS29720 f227278c3abbf4132f25a8f85e22b5af 188 Pfam PF05685 Putative restriction endonuclease 29 184 4.7E-22 T 29-03-2018 IPR008538 Domain of unknown function DUF820 SMALA_RS42695 f571796983ff9d2c989128f853e71966 259 SUPERFAMILY SSF56281 23 220 3.28E-34 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS42695 f571796983ff9d2c989128f853e71966 259 Gene3D G3DSA:3.60.15.10 10 221 2.4E-35 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS42695 f571796983ff9d2c989128f853e71966 259 SMART SM00849 26 215 4.3E-17 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS42695 f571796983ff9d2c989128f853e71966 259 Pfam PF00753 Metallo-beta-lactamase superfamily 27 215 5.8E-23 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS08420 57d668f51f621539e7d09ff818800e6f 69 Pfam PF04149 Domain of unknown function (DUF397) 10 64 5.1E-25 T 29-03-2018 IPR007278 Domain of unknown function DUF397 SMALA_RS30420 26383c92677580b4c6620e511b5f57d3 132 SUPERFAMILY SSF55874 29 125 9.97E-6 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS30420 26383c92677580b4c6620e511b5f57d3 132 Pfam PF13581 Histidine kinase-like ATPase domain 9 124 3.7E-9 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS30420 26383c92677580b4c6620e511b5f57d3 132 Gene3D G3DSA:3.30.565.10 2 132 2.3E-11 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS15960 ca305f2df37f5eec38184309f2e242db 397 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 12 370 1.2E-116 T 29-03-2018 IPR008257 Renal dipeptidase family GO:0006508|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 SMALA_RS15960 ca305f2df37f5eec38184309f2e242db 397 Gene3D G3DSA:3.20.20.140 2 397 2.3E-145 T 29-03-2018 SMALA_RS15960 ca305f2df37f5eec38184309f2e242db 397 SUPERFAMILY SSF51556 293 381 8.43E-105 T 29-03-2018 IPR032466 Metal-dependent hydrolase SMALA_RS15960 ca305f2df37f5eec38184309f2e242db 397 SUPERFAMILY SSF51556 6 253 8.43E-105 T 29-03-2018 IPR032466 Metal-dependent hydrolase SMALA_RS06300 00381ba4c9e3f49748d2b10a0806e5dd 97 Pfam PF02416 mttA/Hcf106 family 8 55 1.6E-17 T 29-03-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 SMALA_RS06300 00381ba4c9e3f49748d2b10a0806e5dd 97 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 5 51 1.0E-16 T 29-03-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 SMALA_RS06300 00381ba4c9e3f49748d2b10a0806e5dd 97 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 3 79 18.109 T 29-03-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 SMALA_RS24785 9ddc5af68c458e392d61036d18596b10 443 SUPERFAMILY SSF48452 205 407 5.22E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS24785 9ddc5af68c458e392d61036d18596b10 443 Gene3D G3DSA:1.25.40.10 149 440 4.5E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS35925 7b803c0300df65d55eb7759c0f4e1ded 481 Pfam PF06762 Lipase maturation factor 293 472 1.4E-61 T 29-03-2018 IPR009613 Lipase maturation factor Reactome: R-HSA-8963889 SMALA_RS35925 7b803c0300df65d55eb7759c0f4e1ded 481 Pfam PF06762 Lipase maturation factor 121 269 4.9E-60 T 29-03-2018 IPR009613 Lipase maturation factor Reactome: R-HSA-8963889 SMALA_RS07660 f07b3e1395f8f768e727d29b86493b82 138 Pfam PF07811 TadE-like protein 16 56 5.0E-8 T 29-03-2018 IPR012495 TadE-like SMALA_RS23445 c585033b474b04beef25ce90c42e54d1 270 SUPERFAMILY SSF161098 4 268 3.01E-50 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS23445 c585033b474b04beef25ce90c42e54d1 270 Gene3D G3DSA:1.10.3720.10 1 260 5.6E-32 T 29-03-2018 SMALA_RS23445 c585033b474b04beef25ce90c42e54d1 270 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 100 264 4.9E-9 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS30210 d86e90c46bf3279410a8eb57c363eeb8 517 Pfam PF05036 Sporulation related domain 79 146 1.2E-6 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 SMALA_RS30210 d86e90c46bf3279410a8eb57c363eeb8 517 Gene3D G3DSA:3.30.70.1070 77 148 8.5E-7 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 SMALA_RS30210 d86e90c46bf3279410a8eb57c363eeb8 517 Pfam PF09992 Phosphodiester glycosidase 327 514 9.7E-32 T 29-03-2018 IPR018711 Phosphodiester glycosidase SMALA_RS30210 d86e90c46bf3279410a8eb57c363eeb8 517 SUPERFAMILY SSF110997 79 147 1.22E-5 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 SMALA_RS21775 765c4072b68185decd4be0f8bbb00efa 271 Pfam PF15698 Phosphatase 7 269 2.6E-112 T 29-03-2018 IPR031423 Uncharacterised phosphatase SCO2771 SMALA_RS15345 3348869123bde53444195832841c3e6c 95 Pfam PF11238 Protein of unknown function (DUF3039) 26 81 7.5E-32 T 29-03-2018 IPR021400 Protein of unknown function DUF3039 SMALA_RS25330 5052ff6ef946ec27eb765bca1f1d644a 549 Pfam PF07690 Major Facilitator Superfamily 14 408 6.8E-42 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS25330 5052ff6ef946ec27eb765bca1f1d644a 549 Gene3D G3DSA:1.20.1250.20 250 502 1.8E-29 T 29-03-2018 SMALA_RS25330 5052ff6ef946ec27eb765bca1f1d644a 549 SUPERFAMILY SSF103473 10 200 6.67E-57 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS25330 5052ff6ef946ec27eb765bca1f1d644a 549 SUPERFAMILY SSF103473 247 418 6.67E-57 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS25330 5052ff6ef946ec27eb765bca1f1d644a 549 SUPERFAMILY SSF103473 461 491 6.67E-57 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS25330 5052ff6ef946ec27eb765bca1f1d644a 549 Gene3D G3DSA:1.20.1250.20 3 192 3.6E-27 T 29-03-2018 SMALA_RS28890 5ccdc960fe817ccf529df32eb7480145 257 Gene3D G3DSA:3.40.830.10 1 257 1.9E-44 T 29-03-2018 SMALA_RS28890 5ccdc960fe817ccf529df32eb7480145 257 SUPERFAMILY SSF53213 11 255 2.49E-8 T 29-03-2018 SMALA_RS36170 90dd022eabe2bf3daf38f2118019f4a5 247 Pfam PF01927 Mut7-C RNAse domain 90 231 4.7E-42 T 29-03-2018 IPR002782 Mut7-C RNAse domain SMALA_RS36170 90dd022eabe2bf3daf38f2118019f4a5 247 Pfam PF14451 Mut7-C ubiquitin 4 82 1.1E-23 T 29-03-2018 IPR027798 Ubiquitin Mut7-C domain SMALA_RS19280 1da9872bfa61757e5b42b3bfcb20644f 167 Gene3D G3DSA:3.30.565.10 2 155 1.1E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS19280 1da9872bfa61757e5b42b3bfcb20644f 167 SUPERFAMILY SSF55874 121 149 1.19E-12 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS19280 1da9872bfa61757e5b42b3bfcb20644f 167 SUPERFAMILY SSF55874 32 86 1.19E-12 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS19280 1da9872bfa61757e5b42b3bfcb20644f 167 Pfam PF13581 Histidine kinase-like ATPase domain 11 150 1.1E-23 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS14370 807051e6a98b8ea7be84660609279d40 250 Gene3D G3DSA:1.10.1780.10 90 241 1.9E-35 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 SMALA_RS14370 807051e6a98b8ea7be84660609279d40 250 SUPERFAMILY SSF81923 100 235 2.35E-22 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 SMALA_RS14370 807051e6a98b8ea7be84660609279d40 250 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 113 164 1.5E-7 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 SMALA_RS14370 807051e6a98b8ea7be84660609279d40 250 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 189 235 1.8E-11 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 SMALA_RS15250 91bcbf0902cf576df5085a7fcefeef17 741 SUPERFAMILY SSF52540 345 599 1.28E-12 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS10810 37985931fec3c8117e343e3ea015717b 146 Pfam PF03779 SPW repeat 37 84 1.8E-17 T 29-03-2018 IPR005530 SPW repeat SMALA_RS10810 37985931fec3c8117e343e3ea015717b 146 Pfam PF03779 SPW repeat 93 138 1.2E-12 T 29-03-2018 IPR005530 SPW repeat SMALA_RS43180 d68f7e43ca80d6e7dfbef1b0dcda7d92 699 Gene3D G3DSA:1.20.120.330 391 531 2.7E-4 T 29-03-2018 SMALA_RS24230 ae37463fde86eae501bea49fcbba9b82 612 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 35 60 2.0E-20 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 SMALA_RS24230 ae37463fde86eae501bea49fcbba9b82 612 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 274 293 2.0E-20 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 SMALA_RS24230 ae37463fde86eae501bea49fcbba9b82 612 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 105 123 2.0E-20 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 SMALA_RS24230 ae37463fde86eae501bea49fcbba9b82 612 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 470 485 2.0E-20 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 SMALA_RS24230 ae37463fde86eae501bea49fcbba9b82 612 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 123 142 2.0E-20 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 SMALA_RS24230 ae37463fde86eae501bea49fcbba9b82 612 Pfam PF01019 Gamma-glutamyltranspeptidase 28 605 5.8E-111 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 SMALA_RS24230 ae37463fde86eae501bea49fcbba9b82 612 SUPERFAMILY SSF56235 411 611 1.54E-125 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SMALA_RS24230 ae37463fde86eae501bea49fcbba9b82 612 SUPERFAMILY SSF56235 2 358 1.54E-125 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SMALA_RS29650 f6b65b3c8c2649aa0f1124b8d4a86458 293 Gene3D G3DSA:2.120.10.30 21 287 2.0E-36 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like SMALA_RS29650 f6b65b3c8c2649aa0f1124b8d4a86458 293 SUPERFAMILY SSF63829 9 279 1.29E-52 T 29-03-2018 SMALA_RS29650 f6b65b3c8c2649aa0f1124b8d4a86458 293 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 135 157 3.7E-17 T 29-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) SMALA_RS29650 f6b65b3c8c2649aa0f1124b8d4a86458 293 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 158 178 3.7E-17 T 29-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) SMALA_RS29650 f6b65b3c8c2649aa0f1124b8d4a86458 293 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 196 213 3.7E-17 T 29-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) SMALA_RS29650 f6b65b3c8c2649aa0f1124b8d4a86458 293 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 94 115 3.7E-17 T 29-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) SMALA_RS29650 f6b65b3c8c2649aa0f1124b8d4a86458 293 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 15 253 3.3E-61 T 29-03-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region SMALA_RS06430 335f6cb0e3d424f68892206e19ac566b 340 Gene3D G3DSA:3.30.1330.40 63 177 0.18 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SMALA_RS06430 335f6cb0e3d424f68892206e19ac566b 340 SUPERFAMILY SSF55298 220 339 2.02E-11 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SMALA_RS06430 335f6cb0e3d424f68892206e19ac566b 340 TIGRFAM TIGR04444 chori_FkbO_Hyg5: chorismatase, FkbO/Hyg5 family 27 339 7.2E-162 T 29-03-2018 IPR031038 Chorismatase, FkbO/Hyg5 family GO:0055114 SMALA_RS06430 335f6cb0e3d424f68892206e19ac566b 340 Gene3D G3DSA:3.30.1330.40 194 340 4.7E-22 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SMALA_RS25795 62b5b5f0138558290bbe3df4f34de725 198 Pfam PF03352 Methyladenine glycosylase 25 193 1.3E-67 T 29-03-2018 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 SMALA_RS25795 62b5b5f0138558290bbe3df4f34de725 198 SUPERFAMILY SSF48150 14 196 3.61E-67 T 29-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 SMALA_RS25795 62b5b5f0138558290bbe3df4f34de725 198 Gene3D G3DSA:1.10.340.30 13 195 1.6E-74 T 29-03-2018 SMALA_RS25795 62b5b5f0138558290bbe3df4f34de725 198 TIGRFAM TIGR00624 tag: DNA-3-methyladenine glycosylase I 15 194 1.2E-72 T 29-03-2018 IPR004597 DNA-3-methyladenine glycosylase I GO:0006284|GO:0008725 SMALA_RS07650 1b72d67604d324bf20a19299922a579b 147 Pfam PF13400 Putative Flp pilus-assembly TadE/G-like 21 68 5.4E-5 T 29-03-2018 IPR028087 Putative Flp pilus-assembly TadG-like, N-terminal SMALA_RS14870 3ab6cfc08a45f873214eab2eb497ac4d 390 Pfam PF07730 Histidine kinase 193 260 2.9E-13 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMALA_RS14870 3ab6cfc08a45f873214eab2eb497ac4d 390 Gene3D G3DSA:3.30.565.10 249 389 3.5E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS14870 3ab6cfc08a45f873214eab2eb497ac4d 390 SUPERFAMILY SSF55874 293 387 8.36E-12 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS03220 0431aae967c7a8ac45d2b1ea87c296cf 131 Pfam PF11236 Protein of unknown function (DUF3037) 13 130 2.3E-43 T 29-03-2018 IPR021398 Protein of unknown function DUF3037 SMALA_RS00895 509e2bf25ce4567fa0a1e3ddaa01c106 168 Pfam PF07883 Cupin domain 72 144 6.7E-9 T 29-03-2018 IPR013096 Cupin 2, conserved barrel SMALA_RS00895 509e2bf25ce4567fa0a1e3ddaa01c106 168 Gene3D G3DSA:2.60.120.10 22 166 1.7E-17 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SMALA_RS00895 509e2bf25ce4567fa0a1e3ddaa01c106 168 SUPERFAMILY SSF51182 38 160 1.85E-21 T 29-03-2018 IPR011051 RmlC-like cupin domain SMALA_RS42890 c8f86f91a33c8fe03144a90d34cc6865 209 SUPERFAMILY SSF52317 1 183 1.43E-45 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS42890 c8f86f91a33c8fe03144a90d34cc6865 209 Gene3D G3DSA:3.40.50.880 1 208 5.8E-51 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS42890 c8f86f91a33c8fe03144a90d34cc6865 209 Pfam PF01965 DJ-1/PfpI family 2 161 1.9E-24 T 29-03-2018 IPR002818 DJ-1/PfpI SMALA_RS10140 ba6f867cb11597e66bda562b48f4d01b 543 Pfam PF16655 PhoD-like phosphatase, N-terminal domain 40 137 3.0E-32 T 29-03-2018 IPR032093 Phospholipase D, N-terminal SMALA_RS10140 ba6f867cb11597e66bda562b48f4d01b 543 Pfam PF09423 PhoD-like phosphatase 150 507 1.9E-118 T 29-03-2018 IPR018946 Alkaline phosphatase D-related SMALA_RS10140 ba6f867cb11597e66bda562b48f4d01b 543 SUPERFAMILY SSF56300 146 512 3.52E-29 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SMALA_RS10140 ba6f867cb11597e66bda562b48f4d01b 543 Gene3D G3DSA:2.60.40.380 36 141 2.5E-6 T 29-03-2018 SMALA_RS10140 ba6f867cb11597e66bda562b48f4d01b 543 Gene3D G3DSA:3.60.21.10 144 534 5.8E-48 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SMALA_RS28505 c9662ff99141e37404602c02b87823af 242 Gene3D G3DSA:3.40.1190.20 25 233 0.001 T 29-03-2018 IPR029056 Ribokinase-like SMALA_RS37735 79679928de94f0cb2911686016385528 393 Pfam PF05954 Phage late control gene D protein (GPD) 73 376 1.1E-5 T 29-03-2018 SMALA_RS37735 79679928de94f0cb2911686016385528 393 Gene3D G3DSA:2.30.300.10 12 172 0.01 T 29-03-2018 SMALA_RS37735 79679928de94f0cb2911686016385528 393 SUPERFAMILY SSF69279 17 195 7.37E-13 T 29-03-2018 SMALA_RS24970 848d2137c7d57abba2b2520aa1729a28 249 SUPERFAMILY SSF53067 2 246 5.61E-42 T 29-03-2018 SMALA_RS24970 848d2137c7d57abba2b2520aa1729a28 249 Gene3D G3DSA:3.30.420.40 1 114 3.6E-26 T 29-03-2018 SMALA_RS24970 848d2137c7d57abba2b2520aa1729a28 249 Gene3D G3DSA:3.30.420.40 115 248 1.2E-28 T 29-03-2018 SMALA_RS24970 848d2137c7d57abba2b2520aa1729a28 249 Pfam PF00480 ROK family 2 159 1.0E-22 T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 SMALA_RS21660 702265b4776152d917041c1d44a7b6e5 293 Gene3D G3DSA:2.60.40.10 151 287 7.4E-4 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS36870 37944c69ae57ddcee5c18cd66a726432 420 Pfam PF01757 Acyltransferase family 35 389 2.0E-23 T 29-03-2018 IPR002656 Acyltransferase 3 GO:0016747 SMALA_RS16425 e74fb569368b73549a87d3baca00f62b 306 Gene3D G3DSA:3.20.20.140 5 306 1.6E-48 T 29-03-2018 SMALA_RS16425 e74fb569368b73549a87d3baca00f62b 306 SUPERFAMILY SSF51556 25 300 7.03E-78 T 29-03-2018 IPR032466 Metal-dependent hydrolase SMALA_RS16425 e74fb569368b73549a87d3baca00f62b 306 Pfam PF04909 Amidohydrolase 30 300 1.8E-47 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 SMALA_RS23970 f9a4928bf452e31bcf0eee74cd8054bb 621 Gene3D G3DSA:2.130.10.120 455 615 1.7E-5 T 29-03-2018 SMALA_RS23970 f9a4928bf452e31bcf0eee74cd8054bb 621 Gene3D G3DSA:2.130.10.120 201 410 0.049 T 29-03-2018 SMALA_RS23970 f9a4928bf452e31bcf0eee74cd8054bb 621 SUPERFAMILY SSF50998 300 559 5.49E-9 T 29-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily SMALA_RS23970 f9a4928bf452e31bcf0eee74cd8054bb 621 SUPERFAMILY SSF50998 250 273 5.49E-9 T 29-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily SMALA_RS20230 f7452b17ad84c85055b0d050b98078af 210 SUPERFAMILY SSF52540 24 199 2.08E-22 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS20230 f7452b17ad84c85055b0d050b98078af 210 Pfam PF03029 Conserved hypothetical ATP binding protein 31 192 2.8E-21 T 29-03-2018 IPR004130 GPN-loop GTPase SMALA_RS20230 f7452b17ad84c85055b0d050b98078af 210 Gene3D G3DSA:3.40.50.300 16 201 8.0E-19 T 29-03-2018 SMALA_RS35440 cbb07501992f759b1b584a8db8f24c12 456 Gene3D G3DSA:3.50.50.60 3 347 1.4E-24 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS35440 cbb07501992f759b1b584a8db8f24c12 456 Pfam PF01494 FAD binding domain 5 185 1.0E-5 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 SMALA_RS35440 cbb07501992f759b1b584a8db8f24c12 456 SUPERFAMILY SSF51905 304 366 5.19E-25 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS35440 cbb07501992f759b1b584a8db8f24c12 456 SUPERFAMILY SSF51905 5 191 5.19E-25 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS35185 7e659ea6438783213a61d696c1cf9106 170 SUPERFAMILY SSF55811 5 158 1.76E-20 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMALA_RS35185 7e659ea6438783213a61d696c1cf9106 170 ProSitePatterns PS00893 Nudix box signature. 50 71 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 SMALA_RS35185 7e659ea6438783213a61d696c1cf9106 170 Gene3D G3DSA:3.90.79.10 3 165 2.2E-25 T 29-03-2018 SMALA_RS35185 7e659ea6438783213a61d696c1cf9106 170 Pfam PF00293 NUDIX domain 9 154 4.6E-16 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SMALA_RS14415 68fc05ae076aebe00adc36e1df291435 304 SUPERFAMILY SSF161098 38 304 4.06E-60 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS14415 68fc05ae076aebe00adc36e1df291435 304 Gene3D G3DSA:1.10.3720.10 27 291 1.3E-34 T 29-03-2018 SMALA_RS14415 68fc05ae076aebe00adc36e1df291435 304 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 119 289 7.8E-19 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS38285 d254c102c1e0e9242518dbb151022e72 218 Pfam PF09335 SNARE associated Golgi protein 45 172 5.5E-24 T 29-03-2018 IPR032816 SNARE associated Golgi protein SMALA_RS34620 099af4aadbda7638f228f8ff0749693f 177 PIRSF PIRSF010260 3 177 1.2E-60 T 29-03-2018 IPR014457 Uncharacterised conserved protein UCP010260 SMALA_RS34620 099af4aadbda7638f228f8ff0749693f 177 Pfam PF09348 Domain of unknown function (DUF1990) 14 169 1.5E-58 T 29-03-2018 IPR018960 Domain of unknown function DUF1990 SMALA_RS42800 27d131ab442605612d3c51fe679e597a 483 Pfam PF00069 Protein kinase domain 15 268 3.9E-33 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMALA_RS42800 27d131ab442605612d3c51fe679e597a 483 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 21 43 - T 29-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 SMALA_RS42800 27d131ab442605612d3c51fe679e597a 483 SMART SM00220 15 271 5.2E-36 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMALA_RS42800 27d131ab442605612d3c51fe679e597a 483 Gene3D G3DSA:1.10.510.10 10 276 9.7E-51 T 29-03-2018 SMALA_RS42800 27d131ab442605612d3c51fe679e597a 483 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 134 146 - T 29-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMALA_RS42800 27d131ab442605612d3c51fe679e597a 483 SUPERFAMILY SSF56112 11 270 2.56E-55 T 29-03-2018 IPR011009 Protein kinase-like domain SMALA_RS07860 746ef443b8c4349a4c4fcd13ea152c6e 384 SUPERFAMILY SSF52540 140 379 6.83E-18 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS07860 746ef443b8c4349a4c4fcd13ea152c6e 384 Gene3D G3DSA:3.40.50.300 137 378 5.1E-18 T 29-03-2018 SMALA_RS12965 a517fe0b03c6b720e87570e265e91cf4 273 Pfam PF11296 Protein of unknown function (DUF3097) 9 270 1.1E-127 T 29-03-2018 IPR021447 Protein of unknown function DUF3097 SMALA_RS22875 5bca5297c0d7a461e39991df34a952a2 105 Gene3D G3DSA:1.20.58.60 7 104 4.5E-4 T 29-03-2018 SMALA_RS01645 4fd9643d950f6611de8ddfccb595a7c0 265 SUPERFAMILY SSF52266 30 227 7.75E-37 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain SMALA_RS01645 4fd9643d950f6611de8ddfccb595a7c0 265 Gene3D G3DSA:3.40.50.1110 33 240 3.8E-37 T 29-03-2018 SMALA_RS01645 4fd9643d950f6611de8ddfccb595a7c0 265 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 43 216 1.6E-21 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain SMALA_RS23720 b64ed0ca89cb8782b92917f90afa77d8 177 Pfam PF16976 Flp pilus assembly protein RcpC/CpaB 50 174 4.5E-8 T 29-03-2018 IPR031571 Flp pilus assembly protein RcpC/CpaB domain SMALA_RS36670 39434e65fd4db2170263f31fa4e427b7 283 SUPERFAMILY SSF53335 6 265 4.48E-58 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS36670 39434e65fd4db2170263f31fa4e427b7 283 Pfam PF04072 Leucine carboxyl methyltransferase 12 185 2.8E-46 T 29-03-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 SMALA_RS36670 39434e65fd4db2170263f31fa4e427b7 283 Gene3D G3DSA:3.40.50.150 6 268 9.2E-41 T 29-03-2018 SMALA_RS36670 39434e65fd4db2170263f31fa4e427b7 283 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 8 261 1.4E-57 T 29-03-2018 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 SMALA_RS03440 06f6f8a76f80bb138866ed02789fa9d1 281 Gene3D G3DSA:1.10.3720.10 12 277 1.7E-39 T 29-03-2018 SMALA_RS03440 06f6f8a76f80bb138866ed02789fa9d1 281 SUPERFAMILY SSF161098 21 268 4.58E-45 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS03440 06f6f8a76f80bb138866ed02789fa9d1 281 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 270 8.7E-19 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS00030 162b54621476726ca987afc04fcc5fc3 95 Gene3D G3DSA:1.10.10.60 15 79 3.4E-4 T 29-03-2018 SMALA_RS13650 ac0ec15039cac0b230329433229cc8df 218 Gene3D G3DSA:3.40.50.1820 2 202 6.4E-12 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS13650 ac0ec15039cac0b230329433229cc8df 218 SUPERFAMILY SSF53474 17 198 1.8E-22 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS13650 ac0ec15039cac0b230329433229cc8df 218 Pfam PF00975 Thioesterase domain 27 130 1.8E-19 T 29-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 SMALA_RS15735 a6510dff68a43b8d56ad22e43595342c 785 Gene3D G3DSA:3.40.50.300 144 553 6.9E-8 T 29-03-2018 SMALA_RS15735 a6510dff68a43b8d56ad22e43595342c 785 SUPERFAMILY SSF52540 277 464 2.61E-7 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS37140 b52b6bbb8eafbe91cbf96a0db8b0b7e3 349 Gene3D G3DSA:1.20.1630.10 52 326 9.8E-47 T 29-03-2018 SMALA_RS37140 b52b6bbb8eafbe91cbf96a0db8b0b7e3 349 Pfam PF03916 Polysulphide reductase, NrfD 71 232 2.4E-10 T 29-03-2018 IPR005614 NrfD family SMALA_RS36825 96fe0b3465e9d8b3b397753ee6993e9f 311 Pfam PF01435 Peptidase family M48 114 205 3.9E-10 T 29-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 SMALA_RS36825 96fe0b3465e9d8b3b397753ee6993e9f 311 Gene3D G3DSA:3.30.2010.10 109 197 5.9E-17 T 29-03-2018 SMALA_RS18060 272a73b6ba35ab14b32b8473e36a260f 245 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 48 208 2.2E-22 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS18060 272a73b6ba35ab14b32b8473e36a260f 245 SUPERFAMILY SSF161098 21 203 1.05E-34 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS18060 272a73b6ba35ab14b32b8473e36a260f 245 Gene3D G3DSA:1.10.3720.10 2 221 6.3E-28 T 29-03-2018 SMALA_RS09470 cf4b8a2cc8a2513d1392867ce3542a6d 107 SUPERFAMILY SSF50022 4 105 1.44E-32 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMALA_RS09470 cf4b8a2cc8a2513d1392867ce3542a6d 107 Pfam PF00355 Rieske [2Fe-2S] domain 6 91 2.2E-21 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMALA_RS09470 cf4b8a2cc8a2513d1392867ce3542a6d 107 Gene3D G3DSA:2.102.10.10 1 107 1.2E-28 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMALA_RS09075 45ba881ebc4929b15ac8a09482bd4098 269 Pfam PF02104 SURF1 family 19 231 3.1E-35 T 29-03-2018 IPR002994 Surfeit locus 1/Shy1 GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMALA_RS36755 1e8343cdc439a3a84e2b017e961d80f5 145 Gene3D G3DSA:3.10.450.50 1 144 2.4E-21 T 29-03-2018 SMALA_RS36755 1e8343cdc439a3a84e2b017e961d80f5 145 Pfam PF12680 SnoaL-like domain 16 131 9.3E-14 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain SMALA_RS36755 1e8343cdc439a3a84e2b017e961d80f5 145 SUPERFAMILY SSF54427 3 138 2.45E-18 T 29-03-2018 IPR032710 NTF2-like domain SMALA_RS08490 de9c46d0c87badc8ddd83dcf1870d121 303 SUPERFAMILY SSF53474 67 257 1.43E-30 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS08490 de9c46d0c87badc8ddd83dcf1870d121 303 Gene3D G3DSA:3.40.50.1820 20 303 6.2E-33 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS08490 de9c46d0c87badc8ddd83dcf1870d121 303 Pfam PF01674 Lipase (class 2) 69 243 6.1E-16 T 29-03-2018 IPR002918 Lipase EstA/Esterase EstB GO:0016787 KEGG: 00561+3.1.1.3|MetaCyc: PWY-6857 SMALA_RS00130 f1ec8dc2ffe4eb4a1c632bd791a08401 286 SUPERFAMILY SSF53474 157 222 1.29E-7 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS00130 f1ec8dc2ffe4eb4a1c632bd791a08401 286 Gene3D G3DSA:3.40.50.1820 144 272 2.2E-8 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS26365 7281e329e4c545fa7890d143cc1c691d 536 TIGRFAM TIGR00831 a_cpa1: Na+/H+ antiporter 7 526 1.0E-99 T 29-03-2018 IPR004705 Cation/H+ exchanger, CPA1 family, bacteria GO:0006812|GO:0015299|GO:0016021 SMALA_RS26365 7281e329e4c545fa7890d143cc1c691d 536 Pfam PF00999 Sodium/hydrogen exchanger family 9 402 9.8E-59 T 29-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 SMALA_RS02940 a90b322f66761054191220a65a837789 333 Pfam PF07070 SpoOM protein 3 217 4.9E-77 T 29-03-2018 IPR009776 Sporulation stage 0, protein M SMALA_RS11930 db8e27c638ac7a85611cccb94a23b94c 191 Pfam PF02342 TerD domain 3 187 4.2E-85 T 29-03-2018 IPR003325 TerD domain GO:0006950 SMALA_RS11930 db8e27c638ac7a85611cccb94a23b94c 191 Gene3D G3DSA:2.60.60.30 19 186 1.5E-66 T 29-03-2018 SMALA_RS32565 cc3a5d25753861b74a2d14d87b6cb8ca 262 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 32 218 2.8E-18 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS32565 cc3a5d25753861b74a2d14d87b6cb8ca 262 SUPERFAMILY SSF161098 8 202 6.41E-43 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS32565 cc3a5d25753861b74a2d14d87b6cb8ca 262 Gene3D G3DSA:1.10.3720.10 4 218 4.8E-33 T 29-03-2018 SMALA_RS33350 16d60d3ae39dbd5456127f24193e642f 210 SUPERFAMILY SSF48150 39 174 2.79E-11 T 29-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 SMALA_RS33350 16d60d3ae39dbd5456127f24193e642f 210 Gene3D G3DSA:1.10.340.30 27 146 1.1E-8 T 29-03-2018 SMALA_RS35065 c807cb9eb20b3a890a61a5a27d9cb0c2 324 Pfam PF03640 Secreted repeat of unknown function 216 257 4.5E-13 T 29-03-2018 IPR005297 Lipoprotein repeat SMALA_RS35065 c807cb9eb20b3a890a61a5a27d9cb0c2 324 Pfam PF03640 Secreted repeat of unknown function 274 315 9.2E-14 T 29-03-2018 IPR005297 Lipoprotein repeat SMALA_RS35065 c807cb9eb20b3a890a61a5a27d9cb0c2 324 Pfam PF03640 Secreted repeat of unknown function 92 132 5.0E-14 T 29-03-2018 IPR005297 Lipoprotein repeat SMALA_RS35065 c807cb9eb20b3a890a61a5a27d9cb0c2 324 Pfam PF03640 Secreted repeat of unknown function 150 191 2.2E-16 T 29-03-2018 IPR005297 Lipoprotein repeat SMALA_RS25905 91751771f13fbd213d5c15ded7748893 288 Pfam PF12697 Alpha/beta hydrolase family 40 279 1.2E-16 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS25905 91751771f13fbd213d5c15ded7748893 288 SUPERFAMILY SSF53474 26 285 5.94E-39 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS25905 91751771f13fbd213d5c15ded7748893 288 Gene3D G3DSA:3.40.50.1820 8 288 8.5E-36 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS31715 86bf99afb0e7e91a5dd1dc2b9019ca1b 144 Pfam PF14552 Tautomerase enzyme 38 115 1.2E-15 T 29-03-2018 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 SMALA_RS31715 86bf99afb0e7e91a5dd1dc2b9019ca1b 144 Gene3D G3DSA:3.30.429.10 1 128 7.6E-23 T 29-03-2018 SMALA_RS31715 86bf99afb0e7e91a5dd1dc2b9019ca1b 144 SUPERFAMILY SSF55331 2 124 1.99E-29 T 29-03-2018 IPR014347 Tautomerase/MIF superfamily SMALA_RS23395 2ed337f17de8080d3c866ceb205fead2 244 Pfam PF01925 Sulfite exporter TauE/SafE 13 235 7.0E-18 T 29-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 SMALA_RS40750 4d6bf59de95f55b18fb39cd6834a5752 340 Pfam PF09084 NMT1/THI5 like 88 257 2.6E-14 T 29-03-2018 IPR015168 SsuA/THI5-like SMALA_RS40750 4d6bf59de95f55b18fb39cd6834a5752 340 Gene3D G3DSA:3.40.190.10 161 339 4.9E-20 T 29-03-2018 SMALA_RS40750 4d6bf59de95f55b18fb39cd6834a5752 340 Gene3D G3DSA:3.40.190.10 51 160 4.8E-5 T 29-03-2018 SMALA_RS40750 4d6bf59de95f55b18fb39cd6834a5752 340 SUPERFAMILY SSF53850 55 276 7.85E-31 T 29-03-2018 SMALA_RS05985 7473d53883024a9bcfb227c5a02d72e5 277 Pfam PF03988 Repeat of Unknown Function (DUF347) 149 193 1.2E-14 T 29-03-2018 IPR007136 Protein of unknown function DUF347 SMALA_RS05985 7473d53883024a9bcfb227c5a02d72e5 277 Pfam PF03988 Repeat of Unknown Function (DUF347) 65 133 1.4E-15 T 29-03-2018 IPR007136 Protein of unknown function DUF347 SMALA_RS05985 7473d53883024a9bcfb227c5a02d72e5 277 Pfam PF03988 Repeat of Unknown Function (DUF347) 204 259 2.4E-15 T 29-03-2018 IPR007136 Protein of unknown function DUF347 SMALA_RS05985 7473d53883024a9bcfb227c5a02d72e5 277 Pfam PF03988 Repeat of Unknown Function (DUF347) 10 61 4.7E-15 T 29-03-2018 IPR007136 Protein of unknown function DUF347 SMALA_RS28290 da15cd4e008ddfed29a98ad86ce76ee4 491 Pfam PF00474 Sodium:solute symporter family 33 420 8.6E-37 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 SMALA_RS02035 5d994f20845b8b171d6f7bf6cf73ce23 340 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 4 325 8.4E-63 T 29-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 SMALA_RS12205 70448d43d103abae4f7a53e29fe7be9d 73 Gene3D G3DSA:2.40.10.10 1 72 1.0E-6 T 29-03-2018 SMALA_RS34010 5932ee58d4a5759e8775af2dbdbb493d 359 Pfam PF00487 Fatty acid desaturase 74 332 1.3E-37 T 29-03-2018 IPR005804 Fatty acid desaturase domain GO:0006629 SMALA_RS34010 5932ee58d4a5759e8775af2dbdbb493d 359 PIRSF PIRSF015921 24 359 9.8E-70 T 29-03-2018 IPR012171 Fatty acid desaturase GO:0006629|GO:0016021|GO:0016491 SMALA_RS09100 f4faccc78a5460a5d9bd3e2b206f1435 133 Pfam PF03780 Asp23 family, cell envelope-related function 7 111 6.9E-8 T 29-03-2018 IPR005531 Alkaline shock protein Asp23 SMALA_RS01010 7561a76f6311ce419d18e0a229082c32 203 SUPERFAMILY SSF53254 26 194 2.57E-26 T 29-03-2018 IPR029033 Histidine phosphatase superfamily SMALA_RS01010 7561a76f6311ce419d18e0a229082c32 203 Gene3D G3DSA:3.40.50.1240 14 198 6.7E-19 T 29-03-2018 IPR029033 Histidine phosphatase superfamily SMALA_RS01010 7561a76f6311ce419d18e0a229082c32 203 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 19 193 1.2E-21 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SMALA_RS00380 8446d5e6c99b22fda4ed9070992e73e6 390 Gene3D G3DSA:3.90.226.10 91 172 0.007 T 29-03-2018 SMALA_RS31880 8c9069be2e60c317dca433fbd47ad193 222 Gene3D G3DSA:3.40.190.10 6 219 5.6E-4 T 29-03-2018 SMALA_RS15060 20a7ddf42c12588e70513e63b28adf57 203 Pfam PF09438 Domain of unknown function (DUF2017) 9 201 5.3E-58 T 29-03-2018 IPR018561 Domain of unknown function DUF2017 SMALA_RS18985 40b6f1dfa3d9571a00b289201755660b 315 Gene3D G3DSA:3.30.2010.10 95 191 1.7E-20 T 29-03-2018 SMALA_RS18985 40b6f1dfa3d9571a00b289201755660b 315 Pfam PF01435 Peptidase family M48 119 187 4.4E-10 T 29-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 SMALA_RS21095 c1073d544ad0a1d15c15a3f14a353aff 401 SUPERFAMILY SSF51261 193 394 1.15E-41 T 29-03-2018 IPR011055 Duplicated hybrid motif SMALA_RS21095 c1073d544ad0a1d15c15a3f14a353aff 401 Pfam PF01551 Peptidase family M23 296 390 2.3E-24 T 29-03-2018 IPR016047 Peptidase M23 SMALA_RS21095 c1073d544ad0a1d15c15a3f14a353aff 401 Gene3D G3DSA:2.70.70.10 225 397 2.4E-43 T 29-03-2018 SMALA_RS23930 9dad010be41c25cd62947fe8f8f14765 592 Pfam PF16192 C-terminal four TMM region of protein-O-mannosyltransferase 398 591 7.8E-24 T 29-03-2018 IPR032421 Protein O-mannosyl-transferase, C-terminal four TM domain KEGG: 00500+2.4.1.10|KEGG: 00514+2.4.1.109|KEGG: 00515+2.4.1.109|MetaCyc: PWY-822|Reactome: R-HSA-5173105 SMALA_RS23930 9dad010be41c25cd62947fe8f8f14765 592 Pfam PF02366 Dolichyl-phosphate-mannose-protein mannosyltransferase 271 305 1.5E-4 T 29-03-2018 IPR003342 Glycosyl transferase family 39/83 GO:0000030|GO:0006493|GO:0016020 Reactome: R-HSA-5173105 SMALA_RS23930 9dad010be41c25cd62947fe8f8f14765 592 Pfam PF02366 Dolichyl-phosphate-mannose-protein mannosyltransferase 82 233 1.5E-12 T 29-03-2018 IPR003342 Glycosyl transferase family 39/83 GO:0000030|GO:0006493|GO:0016020 Reactome: R-HSA-5173105 SMALA_RS07855 0b17185f72f7d4ebf771cffe46768779 454 TIGRFAM TIGR03920 T7SS_EccD: type VII secretion integral membrane protein EccD 15 449 5.5E-31 T 29-03-2018 IPR006707 Type VII secretion system membrane protein EccD SMALA_RS07855 0b17185f72f7d4ebf771cffe46768779 454 Pfam PF08817 WXG100 protein secretion system (Wss), protein YukD 13 85 9.2E-16 T 29-03-2018 IPR024962 YukD-like SMALA_RS05570 a98a24fc771de6bc92be13cc6209b3ea 209 Pfam PF09335 SNARE associated Golgi protein 38 164 1.3E-20 T 29-03-2018 IPR032816 SNARE associated Golgi protein SMALA_RS14810 5ef6d35724d96d04a06c3b0479a1563d 294 SMART SM00530 17 83 0.0066 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMALA_RS14810 5ef6d35724d96d04a06c3b0479a1563d 294 Pfam PF13560 Helix-turn-helix domain 13 80 1.6E-11 T 29-03-2018 SMALA_RS14810 5ef6d35724d96d04a06c3b0479a1563d 294 Gene3D G3DSA:1.10.260.40 12 106 4.5E-10 T 29-03-2018 SMALA_RS26615 a95d6e33f28d3d6d39c48033b8d02699 163 SUPERFAMILY SSF103196 13 152 1.67E-20 T 29-03-2018 SMALA_RS26615 a95d6e33f28d3d6d39c48033b8d02699 163 Pfam PF03259 Roadblock/LC7 domain 18 58 9.6E-6 T 29-03-2018 IPR004942 Roadblock/LAMTOR2 domain SMALA_RS26615 a95d6e33f28d3d6d39c48033b8d02699 163 Pfam PF03259 Roadblock/LC7 domain 70 121 2.6E-7 T 29-03-2018 IPR004942 Roadblock/LAMTOR2 domain SMALA_RS26615 a95d6e33f28d3d6d39c48033b8d02699 163 Gene3D G3DSA:3.30.450.30 13 155 1.7E-47 T 29-03-2018 SMALA_RS26615 a95d6e33f28d3d6d39c48033b8d02699 163 SMART SM00960 18 123 4.6E-13 T 29-03-2018 IPR004942 Roadblock/LAMTOR2 domain SMALA_RS29920 147f54c662700ad9e7f1e12531a841b1 439 SUPERFAMILY SSF88713 110 154 1.45E-22 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 SMALA_RS29920 147f54c662700ad9e7f1e12531a841b1 439 SUPERFAMILY SSF88713 184 413 1.45E-22 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 SMALA_RS29920 147f54c662700ad9e7f1e12531a841b1 439 Gene3D G3DSA:3.20.20.370 92 420 8.6E-35 T 29-03-2018 SMALA_RS00615 ce342907e562d64a6f3b4aeceda8accf 484 Pfam PF09594 Glycosyltransferase family 87 176 391 9.1E-6 T 29-03-2018 IPR018584 Glycosyltransferase family 87 GO:0016758 SMALA_RS00615 ce342907e562d64a6f3b4aeceda8accf 484 Gene3D G3DSA:3.10.129.10 187 309 0.032 T 29-03-2018 SMALA_RS24455 8e00818faaa690f62cc573b20218184c 319 SUPERFAMILY SSF161098 90 295 1.09E-20 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS24455 8e00818faaa690f62cc573b20218184c 319 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 312 5.1E-39 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS24455 8e00818faaa690f62cc573b20218184c 319 Gene3D G3DSA:1.10.3720.10 3 301 5.4E-41 T 29-03-2018 SMALA_RS06855 ad0a88ca55eec43cd49479d219cee5fa 110 SUPERFAMILY SSF51569 37 85 3.0E-14 T 29-03-2018 SMALA_RS06855 ad0a88ca55eec43cd49479d219cee5fa 110 Pfam PF01474 Class-II DAHP synthetase family 39 82 1.3E-14 T 29-03-2018 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 SMALA_RS32845 ceaa08de7f4a410ee661a609157b682a 192 Pfam PF14280 Domain of unknown function (DUF4365) 38 185 1.3E-23 T 29-03-2018 IPR025375 Domain of unknown function DUF4365 SMALA_RS39450 c409332ae7e400740bb80805320027b6 278 Gene3D G3DSA:3.20.20.60 1 267 7.1E-37 T 29-03-2018 SMALA_RS39450 c409332ae7e400740bb80805320027b6 278 Pfam PF02548 Ketopantoate hydroxymethyltransferase 4 265 3.0E-62 T 29-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 SMALA_RS39450 c409332ae7e400740bb80805320027b6 278 SUPERFAMILY SSF51621 4 264 5.02E-51 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SMALA_RS12315 d28810bf0d8a0292d9c9f37c447b9f85 146 SUPERFAMILY SSF54593 19 135 2.55E-22 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS12315 d28810bf0d8a0292d9c9f37c447b9f85 146 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 20 132 6.0E-10 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMALA_RS12315 d28810bf0d8a0292d9c9f37c447b9f85 146 Gene3D G3DSA:3.10.180.10 15 138 1.1E-20 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS27035 ed0b816c3320efef8df4dddc431fde79 312 Gene3D G3DSA:1.20.120.20 21 187 4.3E-4 T 29-03-2018 SMALA_RS28245 bcb61553e6ed1b53bc5ce6d97514e515 392 Pfam PF01148 Cytidylyltransferase family 132 388 4.3E-63 T 29-03-2018 SMALA_RS28245 bcb61553e6ed1b53bc5ce6d97514e515 392 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 346 372 - T 29-03-2018 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7817 SMALA_RS05510 e3a64799f41908279fae5530b5d30e43 334 Pfam PF03601 Conserved hypothetical protein 698 10 315 5.2E-74 T 29-03-2018 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 SMALA_RS18780 8311ca7d0b150aa74433e67c10e6763d 221 Pfam PF16702 Domain of unknown function (DUF5063) 13 173 1.2E-43 T 29-03-2018 IPR032025 Protein of unknown function DUF5063 SMALA_RS27225 0e92fd8a134da368209ad8a334153edf 370 Gene3D G3DSA:3.40.50.2300 2 197 2.3E-27 T 29-03-2018 SMALA_RS27225 0e92fd8a134da368209ad8a334153edf 370 Pfam PF13458 Periplasmic binding protein 18 340 4.4E-34 T 29-03-2018 IPR028081 Leucine-binding protein domain SMALA_RS27225 0e92fd8a134da368209ad8a334153edf 370 Gene3D G3DSA:3.40.50.2300 198 342 4.2E-8 T 29-03-2018 SMALA_RS27225 0e92fd8a134da368209ad8a334153edf 370 SUPERFAMILY SSF53822 18 349 7.33E-47 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SMALA_RS16420 632b5b64c318507ebda67e9557dc7b42 341 SUPERFAMILY SSF51556 1 331 7.37E-88 T 29-03-2018 IPR032466 Metal-dependent hydrolase SMALA_RS16420 632b5b64c318507ebda67e9557dc7b42 341 Pfam PF04909 Amidohydrolase 3 330 1.1E-52 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 SMALA_RS16420 632b5b64c318507ebda67e9557dc7b42 341 Gene3D G3DSA:3.20.20.140 1 339 2.8E-56 T 29-03-2018 SMALA_RS10645 e3893376a4ef96d4e33ee0e69f4942a2 251 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 251 40.312 T 29-03-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 SMALA_RS10645 e3893376a4ef96d4e33ee0e69f4942a2 251 Pfam PF02654 Cobalamin-5-phosphate synthase 4 246 2.0E-46 T 29-03-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 SMALA_RS32455 e723bdb5ca74e79934399c550d53d230 350 Pfam PF01758 Sodium Bile acid symporter family 80 256 1.2E-41 T 29-03-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 SMALA_RS37105 e560303702806eb0972e588210013208 636 SUPERFAMILY SSF53649 514 550 4.45E-9 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 SMALA_RS37105 e560303702806eb0972e588210013208 636 SUPERFAMILY SSF53649 352 486 4.45E-9 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 SMALA_RS37105 e560303702806eb0972e588210013208 636 Gene3D G3DSA:3.40.720.10 299 585 7.8E-13 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 SMALA_RS16205 eefbac87848eaf6b7e1e29ae84069911 160 Pfam PF04977 Septum formation initiator 44 121 2.4E-16 T 29-03-2018 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 SMALA_RS09000 8d5089805e97a995e7a8daf187ce6dab 468 Pfam PF01523 Putative modulator of DNA gyrase 21 330 7.4E-38 T 29-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 SMALA_RS09000 8d5089805e97a995e7a8daf187ce6dab 468 SUPERFAMILY SSF111283 7 461 4.45E-67 T 29-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 SMALA_RS09000 8d5089805e97a995e7a8daf187ce6dab 468 Gene3D G3DSA:3.30.2290.10 5 218 2.8E-43 T 29-03-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal domain SMALA_RS42715 2f2651a4ab4c2b0e100bcce926428b0c 374 SUPERFAMILY SSF53850 70 333 2.92E-49 T 29-03-2018 SMALA_RS42715 2f2651a4ab4c2b0e100bcce926428b0c 374 Pfam PF13343 Bacterial extracellular solute-binding protein 120 325 1.7E-20 T 29-03-2018 SMALA_RS42715 2f2651a4ab4c2b0e100bcce926428b0c 374 Gene3D G3DSA:3.40.190.10 51 181 6.3E-13 T 29-03-2018 SMALA_RS42715 2f2651a4ab4c2b0e100bcce926428b0c 374 Gene3D G3DSA:3.40.190.10 182 316 1.5E-21 T 29-03-2018 SMALA_RS35720 e68baf165e68b9216c2f3ad98c440b28 359 SUPERFAMILY SSF50952 34 338 2.22E-40 T 29-03-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 SMALA_RS35720 e68baf165e68b9216c2f3ad98c440b28 359 Pfam PF07995 Glucose / Sorbosone dehydrogenase 51 342 2.8E-70 T 29-03-2018 IPR012938 Glucose/Sorbosone dehydrogenase SMALA_RS35720 e68baf165e68b9216c2f3ad98c440b28 359 Gene3D G3DSA:2.120.10.30 280 355 0.021 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like SMALA_RS35720 e68baf165e68b9216c2f3ad98c440b28 359 Gene3D G3DSA:2.120.10.30 26 279 2.8E-58 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like SMALA_RS05515 275fe1cfb9c2d2bff8589689624f41ba 155 Gene3D G3DSA:1.10.10.10 2 155 2.1E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS05515 275fe1cfb9c2d2bff8589689624f41ba 155 Pfam PF01638 HxlR-like helix-turn-helix 19 106 4.3E-21 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type SMALA_RS05515 275fe1cfb9c2d2bff8589689624f41ba 155 SUPERFAMILY SSF46785 5 147 7.28E-38 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS40225 2fa2320e582971a9896b0da3d74d48af 147 Gene3D G3DSA:1.10.10.10 5 138 4.4E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS40225 2fa2320e582971a9896b0da3d74d48af 147 SMART SM00347 31 130 4.4E-4 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS40225 2fa2320e582971a9896b0da3d74d48af 147 SUPERFAMILY SSF46785 12 133 2.62E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS40225 2fa2320e582971a9896b0da3d74d48af 147 Pfam PF12802 MarR family 36 91 5.0E-11 T 29-03-2018 SMALA_RS04145 bf2b806f7318c176678a29ccd229e4a0 177 SUPERFAMILY SSF52540 2 166 8.26E-8 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS04145 bf2b806f7318c176678a29ccd229e4a0 177 Gene3D G3DSA:3.40.50.300 1 169 8.7E-7 T 29-03-2018 SMALA_RS05965 5cbd5a27961e16b2516fba7bb1785659 117 SUPERFAMILY SSF52821 5 110 2.33E-14 T 29-03-2018 IPR001763 Rhodanese-like domain SMALA_RS05965 5cbd5a27961e16b2516fba7bb1785659 117 Gene3D G3DSA:3.40.250.10 2 114 1.7E-10 T 29-03-2018 IPR001763 Rhodanese-like domain SMALA_RS31655 57705e9c998eb284424d13fe64d9f73e 338 SUPERFAMILY SSF103481 59 153 6.41E-12 T 29-03-2018 SMALA_RS31655 57705e9c998eb284424d13fe64d9f73e 338 Pfam PF00892 EamA-like transporter family 161 293 2.6E-18 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SMALA_RS31655 57705e9c998eb284424d13fe64d9f73e 338 Pfam PF00892 EamA-like transporter family 26 150 5.9E-13 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SMALA_RS31655 57705e9c998eb284424d13fe64d9f73e 338 SUPERFAMILY SSF103481 196 300 1.23E-14 T 29-03-2018 SMALA_RS18075 c49bd6511eb824660b9593ca4dec3a11 377 Pfam PF00756 Putative esterase 131 366 9.9E-14 T 29-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 SMALA_RS18075 c49bd6511eb824660b9593ca4dec3a11 377 SUPERFAMILY SSF53474 110 373 8.58E-27 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS18075 c49bd6511eb824660b9593ca4dec3a11 377 Gene3D G3DSA:3.40.50.1820 95 376 8.6E-25 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS42440 9586102f55a40334cd1c7797f35f2b54 132 Gene3D G3DSA:3.10.180.10 1 130 6.7E-23 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS42440 9586102f55a40334cd1c7797f35f2b54 132 SUPERFAMILY SSF54593 1 121 1.09E-24 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS42440 9586102f55a40334cd1c7797f35f2b54 132 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 118 7.0E-12 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMALA_RS22100 f2691814d03adfc55460b545ce429060 274 Pfam PF00877 NlpC/P60 family 172 263 1.7E-21 T 29-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain SMALA_RS22100 f2691814d03adfc55460b545ce429060 274 SUPERFAMILY SSF54001 152 273 3.92E-37 T 29-03-2018 SMALA_RS22100 f2691814d03adfc55460b545ce429060 274 Gene3D G3DSA:3.90.1720.10 153 273 8.3E-30 T 29-03-2018 SMALA_RS24245 64eb869e83bf854b4b75765dd0308649 297 SUPERFAMILY SSF161098 89 276 8.63E-25 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS24245 64eb869e83bf854b4b75765dd0308649 297 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 26 70 3.7E-10 T 29-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain SMALA_RS24245 64eb869e83bf854b4b75765dd0308649 297 Gene3D G3DSA:1.10.3720.10 23 284 5.8E-42 T 29-03-2018 SMALA_RS24245 64eb869e83bf854b4b75765dd0308649 297 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 292 2.1E-26 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS18540 489219eccaa60ae59ccf79cbd94e73c5 126 Pfam PF07811 TadE-like protein 6 48 5.7E-5 T 29-03-2018 IPR012495 TadE-like SMALA_RS16055 fa0b05eb9f265ac5fa8ced71f486e1a3 379 Gene3D G3DSA:3.40.50.720 15 379 2.2E-58 T 29-03-2018 SMALA_RS16055 fa0b05eb9f265ac5fa8ced71f486e1a3 379 SUPERFAMILY SSF51735 26 168 1.12E-34 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS16055 fa0b05eb9f265ac5fa8ced71f486e1a3 379 SUPERFAMILY SSF51735 250 325 1.12E-34 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS16055 fa0b05eb9f265ac5fa8ced71f486e1a3 379 Pfam PF00106 short chain dehydrogenase 32 163 5.4E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS16055 fa0b05eb9f265ac5fa8ced71f486e1a3 379 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 275 292 3.0E-15 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS16055 fa0b05eb9f265ac5fa8ced71f486e1a3 379 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 31 48 3.0E-15 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS16055 fa0b05eb9f265ac5fa8ced71f486e1a3 379 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 104 115 3.0E-15 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SMALA_RS14470 30d8b068180b07f2e0b6bb4152e1b7aa 341 Pfam PF14378 PAP2 superfamily 52 240 3.5E-57 T 29-03-2018 IPR026841 Inositolphosphotransferase Aur1/Ipt1 SMALA_RS02095 c5d106ed011a1b9eb239f6316b10e900 248 Pfam PF13649 Methyltransferase domain 40 133 1.0E-12 T 29-03-2018 SMALA_RS02095 c5d106ed011a1b9eb239f6316b10e900 248 Gene3D G3DSA:3.40.50.150 5 248 1.9E-24 T 29-03-2018 SMALA_RS02095 c5d106ed011a1b9eb239f6316b10e900 248 SUPERFAMILY SSF53335 10 247 3.29E-33 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS06140 adbc51d5aeb1de5570181dfb6415cc49 208 Gene3D G3DSA:3.40.50.850 1 208 1.2E-55 T 29-03-2018 SMALA_RS06140 adbc51d5aeb1de5570181dfb6415cc49 208 SUPERFAMILY SSF52499 5 207 2.22E-59 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SMALA_RS06140 adbc51d5aeb1de5570181dfb6415cc49 208 Pfam PF00857 Isochorismatase family 12 192 6.8E-47 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SMALA_RS18580 7e3817df37e668d49ddcc5f3bac8f442 334 SUPERFAMILY SSF52540 89 244 5.64E-21 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS18580 7e3817df37e668d49ddcc5f3bac8f442 334 SUPERFAMILY SSF52540 1 51 5.64E-21 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS18580 7e3817df37e668d49ddcc5f3bac8f442 334 Gene3D G3DSA:3.40.50.300 1 291 7.6E-34 T 29-03-2018 SMALA_RS18580 7e3817df37e668d49ddcc5f3bac8f442 334 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 7 166 5.0E-6 T 29-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain SMALA_RS05155 6ebd2f9534c00d634dc85262e5c2b275 243 SUPERFAMILY SSF53474 20 86 6.1E-33 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS05155 6ebd2f9534c00d634dc85262e5c2b275 243 SUPERFAMILY SSF53474 119 242 6.1E-33 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS05155 6ebd2f9534c00d634dc85262e5c2b275 243 Gene3D G3DSA:3.40.50.1820 2 242 2.8E-36 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS42515 71f3867ba7ebeefbc8d2f389f4b4107f 361 SUPERFAMILY SSF51679 13 356 1.44E-74 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS42515 71f3867ba7ebeefbc8d2f389f4b4107f 361 Pfam PF00296 Luciferase-like monooxygenase 2 331 1.0E-69 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS42515 71f3867ba7ebeefbc8d2f389f4b4107f 361 Gene3D G3DSA:3.20.20.30 1 360 1.0E-76 T 29-03-2018 SMALA_RS27910 94f0d8eea8818562825e9c2dbd9f0781 154 Pfam PF13826 Domain of unknown function (DUF4188) 9 129 4.2E-42 T 29-03-2018 IPR025444 Monooxygenase af470-like SMALA_RS40125 876845e31e8399bf47763b731ad887f4 328 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 79 315 3.3E-17 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS40125 876845e31e8399bf47763b731ad887f4 328 SUPERFAMILY SSF161098 40 134 1.31E-52 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS40125 876845e31e8399bf47763b731ad887f4 328 SUPERFAMILY SSF161098 175 311 1.31E-52 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS40125 876845e31e8399bf47763b731ad887f4 328 Gene3D G3DSA:1.10.3720.10 1 324 1.6E-49 T 29-03-2018 SMALA_RS04725 aa4532a24518ac33d604569e7acbbc64 292 SUPERFAMILY SSF161098 21 291 7.98E-67 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS04725 aa4532a24518ac33d604569e7acbbc64 292 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 109 283 3.2E-18 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS04725 aa4532a24518ac33d604569e7acbbc64 292 Gene3D G3DSA:1.10.3720.10 17 280 3.7E-41 T 29-03-2018 SMALA_RS37770 77cce4a90d60c615f4d2245f2557d487 704 Gene3D G3DSA:1.20.5.170 544 639 3.0E-6 T 29-03-2018 SMALA_RS32805 19fc66620938e0aec9d1e8c0b5dc0697 137 Pfam PF04686 Streptomyces sporulation and cell division protein, SsgA 23 120 3.6E-38 T 29-03-2018 IPR006776 Sporulation-specific cell division protein SsgB GO:0051301 SMALA_RS09335 dff214c8685bb7c73a46a4cedf9906db 579 Pfam PF00920 Dehydratase family 47 562 3.6E-173 T 29-03-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 SMALA_RS09335 dff214c8685bb7c73a46a4cedf9906db 579 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 130 140 - T 29-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 SMALA_RS09335 dff214c8685bb7c73a46a4cedf9906db 579 SUPERFAMILY SSF52016 382 567 3.53E-57 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel SMALA_RS09335 dff214c8685bb7c73a46a4cedf9906db 579 SUPERFAMILY SSF143975 8 381 1.96E-121 T 29-03-2018 SMALA_RS14460 20a770149d02d5ce6d716f638cfed171 473 Gene3D G3DSA:1.25.40.10 275 370 0.0033 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS14460 20a770149d02d5ce6d716f638cfed171 473 SUPERFAMILY SSF48452 220 302 2.34E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS14460 20a770149d02d5ce6d716f638cfed171 473 SUPERFAMILY SSF48452 351 434 2.34E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS14460 20a770149d02d5ce6d716f638cfed171 473 Gene3D G3DSA:1.25.40.10 371 467 0.018 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS14460 20a770149d02d5ce6d716f638cfed171 473 Gene3D G3DSA:1.10.150.200 189 274 3.4E-4 T 29-03-2018 SMALA_RS26880 723de4dbc562a63b78fd72a807a8a11f 473 Pfam PF00953 Glycosyl transferase family 4 87 246 1.6E-35 T 29-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 SMALA_RS27380 1d26779f5567f84e1111af1e0e0dc818 73 SUPERFAMILY SSF55486 32 68 2.2E-8 T 29-03-2018 SMALA_RS27380 1d26779f5567f84e1111af1e0e0dc818 73 Gene3D G3DSA:1.10.390.10 36 71 7.4E-10 T 29-03-2018 SMALA_RS27380 1d26779f5567f84e1111af1e0e0dc818 73 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 34 65 3.9E-11 T 29-03-2018 IPR001570 Peptidase M4, C-terminal GO:0004222 SMALA_RS21340 4a2d09e86e3ab2be4db9c84901134284 332 Pfam PF01384 Phosphate transporter family 20 319 2.0E-86 T 29-03-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 SMALA_RS09685 48aa9e226509fb1aa9d9d6d71b0af6f5 215 Gene3D G3DSA:3.40.50.300 23 205 0.001 T 29-03-2018 SMALA_RS39635 33aef29bf78f6fcc80688606377bc0c4 434 Pfam PF07158 Dicarboxylate carrier protein MatC N-terminus 2 147 2.5E-30 T 29-03-2018 IPR009827 Dicarboxylate carrier MatC N-terminal SMALA_RS15245 38009727d8d51cd5fd2e0636d9a1875f 83 Gene3D G3DSA:2.10.230.10 19 77 0.0011 T 29-03-2018 SMALA_RS40865 32353598ae74af4536c378dc7a60cf71 179 Gene3D G3DSA:3.40.190.10 19 172 1.3E-4 T 29-03-2018 SMALA_RS34860 f8ff70a8ad4c2d414745834559d9c37e 316 Pfam PF09678 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) 39 280 1.9E-83 T 29-03-2018 IPR019108 Cytochrome c oxidase caa3-type, assembly factor CtaG-related SMALA_RS00295 53aca6322ef476fe0b4b923666010def 372 Pfam PF01594 AI-2E family transporter 30 351 1.1E-49 T 29-03-2018 IPR002549 Transmembrane protein TqsA-like SMALA_RS43015 216a747a2852163f3bc45266fd449d71 326 SUPERFAMILY SSF89550 15 225 1.57E-34 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 SMALA_RS43015 216a747a2852163f3bc45266fd449d71 326 SMART SM00481 18 82 1.3E-5 T 29-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal SMALA_RS43015 216a747a2852163f3bc45266fd449d71 326 Gene3D G3DSA:3.20.20.140 8 210 6.3E-19 T 29-03-2018 SMALA_RS08345 e9f5e8956213fc3e0a9dac67fc7af1a1 270 SUPERFAMILY SSF88713 24 195 1.28E-40 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 SMALA_RS08345 e9f5e8956213fc3e0a9dac67fc7af1a1 270 Gene3D G3DSA:3.20.20.370 12 252 4.0E-47 T 29-03-2018 SMALA_RS08345 e9f5e8956213fc3e0a9dac67fc7af1a1 270 Pfam PF01522 Polysaccharide deacetylase 61 192 3.1E-33 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 SMALA_RS20565 ca66fd00d4faa54b3896eab94af170f4 310 Gene3D G3DSA:1.20.120.450 13 102 3.9E-4 T 29-03-2018 SMALA_RS20565 ca66fd00d4faa54b3896eab94af170f4 310 Gene3D G3DSA:3.90.850.10 103 310 6.9E-63 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 SMALA_RS20565 ca66fd00d4faa54b3896eab94af170f4 310 SUPERFAMILY SSF56529 83 307 5.63E-65 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 SMALA_RS20565 ca66fd00d4faa54b3896eab94af170f4 310 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 96 307 3.8E-63 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 SMALA_RS34420 412e8cf60fae0b9af45473d367ae9a4b 125 Pfam PF00462 Glutaredoxin 41 99 2.1E-10 T 29-03-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 SMALA_RS34420 412e8cf60fae0b9af45473d367ae9a4b 125 Gene3D G3DSA:3.40.30.10 40 114 7.8E-12 T 29-03-2018 SMALA_RS34420 412e8cf60fae0b9af45473d367ae9a4b 125 SUPERFAMILY SSF52833 37 102 1.84E-12 T 29-03-2018 IPR012336 Thioredoxin-like fold SMALA_RS08540 ddafad6e4cf1c0702dbcc7ac0aaaf3f1 296 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 71 134 1.1E-14 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 SMALA_RS08540 ddafad6e4cf1c0702dbcc7ac0aaaf3f1 296 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 290 3.5E-21 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS08540 ddafad6e4cf1c0702dbcc7ac0aaaf3f1 296 Gene3D G3DSA:1.10.3720.10 31 295 4.1E-46 T 29-03-2018 SMALA_RS08540 ddafad6e4cf1c0702dbcc7ac0aaaf3f1 296 SUPERFAMILY SSF161098 72 276 8.9E-42 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS25170 7dd06f9a6e86a39486689b642508e010 217 Gene3D G3DSA:1.10.3630.10 1 193 6.0E-19 T 29-03-2018 SMALA_RS25170 7dd06f9a6e86a39486689b642508e010 217 Pfam PF05719 Golgi phosphoprotein 3 (GPP34) 5 202 7.4E-20 T 29-03-2018 IPR008628 Golgi phosphoprotein 3-like GO:0070273 SMALA_RS42230 0159d2ea0ea71cf94ddf9b6c5d92f5a6 428 Pfam PF13535 ATP-grasp domain 167 311 6.7E-8 T 29-03-2018 SMALA_RS42230 0159d2ea0ea71cf94ddf9b6c5d92f5a6 428 SUPERFAMILY SSF56059 120 343 3.89E-36 T 29-03-2018 SMALA_RS42230 0159d2ea0ea71cf94ddf9b6c5d92f5a6 428 Gene3D G3DSA:3.30.470.20 122 417 8.6E-35 T 29-03-2018 SMALA_RS28895 0abac779df71c9d887fb80a23037ad9e 80 Pfam PF14013 MT0933-like antitoxin protein 16 63 7.5E-14 T 29-03-2018 IPR028037 Antitoxin Rv0909/MT0933 SMALA_RS41690 a049c8ea547b4343c4783ebc1d280b2e 763 Gene3D G3DSA:1.50.10.10 97 575 1.6E-7 T 29-03-2018 SMALA_RS41690 a049c8ea547b4343c4783ebc1d280b2e 763 SUPERFAMILY SSF48208 204 410 2.81E-8 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 SMALA_RS41690 a049c8ea547b4343c4783ebc1d280b2e 763 SUPERFAMILY SSF48208 452 558 2.81E-8 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 SMALA_RS30575 4541ab277af26990bc2ed1f9e4050576 285 Gene3D G3DSA:1.10.10.10 131 271 4.9E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS19740 90f65ca5028e86ec8ed460d50ba6d01c 185 Hamap MF_00630 UPF0232 protein . 3 171 31.646 T 29-03-2018 IPR023007 Uncharacterised protein family UPF0232, actinobacteria SMALA_RS19740 90f65ca5028e86ec8ed460d50ba6d01c 185 Pfam PF05258 Protein of unknown function (DUF721) 70 159 2.0E-25 T 29-03-2018 IPR007922 Protein of unknown function DUF721/UPF0232 SMALA_RS03190 3d78b8bbc74b3a0b027bcf77ee74f0fe 154 Gene3D G3DSA:1.25.40.10 1 133 6.1E-4 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS01125 f8ebbb1c34b0eb4329392bbcc364c6f3 294 SUPERFAMILY SSF81296 31 210 7.7E-40 T 29-03-2018 IPR014756 Immunoglobulin E-set SMALA_RS01125 f8ebbb1c34b0eb4329392bbcc364c6f3 294 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 31 208 3.3E-35 T 29-03-2018 IPR004302 Cellulose/chitin-binding protein, N-terminal SMALA_RS01125 f8ebbb1c34b0eb4329392bbcc364c6f3 294 Gene3D G3DSA:2.70.50.50 31 211 6.5E-46 T 29-03-2018 SMALA_RS16670 f644889843c9b57b8fa746974d8f0875 344 Pfam PF14219 Domain of unknown function (DUF4328) 110 283 6.1E-48 T 29-03-2018 IPR025565 Domain of unknown function DUF4328 SMALA_RS00905 3388c6a8317559dac97730ee480944c9 311 Gene3D G3DSA:3.40.30.10 19 251 9.0E-26 T 29-03-2018 SMALA_RS00905 3388c6a8317559dac97730ee480944c9 311 Pfam PF13743 Thioredoxin 25 179 4.0E-7 T 29-03-2018 SMALA_RS00905 3388c6a8317559dac97730ee480944c9 311 SUPERFAMILY SSF52833 20 183 7.08E-13 T 29-03-2018 IPR012336 Thioredoxin-like fold SMALA_RS13255 926762d17eba6834be68f78015f15e16 394 Pfam PF01757 Acyltransferase family 54 358 6.1E-21 T 29-03-2018 IPR002656 Acyltransferase 3 GO:0016747 SMALA_RS37720 2049b324ca6818e80482af814f8d5ad5 172 Pfam PF06841 T4-like virus tail tube protein gp19 34 154 1.5E-29 T 29-03-2018 IPR010667 Bacteriophage T4, Gp19, tail tube GO:0005198 SMALA_RS37720 2049b324ca6818e80482af814f8d5ad5 172 TIGRFAM TIGR02241 TIGR02241: conserved hypothetical phage tail region protein 4 154 1.5E-27 T 29-03-2018 IPR011747 Conserved hypothetical protein CHP02241 SMALA_RS29065 93b9c5ecff2f671ea7b24406d13da097 148 Pfam PF04341 Protein of unknown function, DUF485 52 136 1.6E-25 T 29-03-2018 IPR007436 Protein of unknown function DUF485 SMALA_RS10635 f123dff880d3483461ee227408054a73 399 SUPERFAMILY SSF52540 224 397 3.93E-39 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS10635 f123dff880d3483461ee227408054a73 399 Gene3D G3DSA:3.60.15.10 1 92 4.8E-5 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS10635 f123dff880d3483461ee227408054a73 399 Pfam PF02283 Cobinamide kinase / cobinamide phosphate guanyltransferase 224 396 2.9E-51 T 29-03-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00030+2.7.1.15|KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 SMALA_RS10635 f123dff880d3483461ee227408054a73 399 Gene3D G3DSA:3.40.50.300 224 398 2.8E-54 T 29-03-2018 SMALA_RS10635 f123dff880d3483461ee227408054a73 399 SUPERFAMILY SSF56281 2 188 3.06E-5 T 29-03-2018 IPR001279 Metallo-beta-lactamase SMALA_RS04860 32c5cca6eedf8bc67615952f8926217c 139 Gene3D G3DSA:3.30.1330.40 6 135 2.8E-29 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SMALA_RS04860 32c5cca6eedf8bc67615952f8926217c 139 SUPERFAMILY SSF55298 5 131 1.3E-31 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SMALA_RS04860 32c5cca6eedf8bc67615952f8926217c 139 Pfam PF01042 Endoribonuclease L-PSP 15 128 1.1E-19 T 29-03-2018 IPR006175 YjgF/YER057c/UK114 family SMALA_RS28295 541e39278a60666648eb00b779807b2f 531 Pfam PF13556 PucR C-terminal helix-turn-helix domain 472 529 9.9E-21 T 29-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain SMALA_RS28295 541e39278a60666648eb00b779807b2f 531 Pfam PF07905 Purine catabolism regulatory protein-like family 16 135 6.6E-25 T 29-03-2018 IPR012914 Purine catabolism PurC-like domain SMALA_RS24640 5471727d4550e7167d0e64894fbd9aaa 193 Gene3D G3DSA:3.40.190.10 4 176 1.4E-7 T 29-03-2018 SMALA_RS20485 4c5887cd8ff0dbb919f60c2104c547a1 245 Pfam PF05988 Bacterial protein of unknown function (DUF899) 5 223 1.8E-80 T 29-03-2018 IPR010296 Protein of unknown function DUF899, thioredoxin-like SMALA_RS20485 4c5887cd8ff0dbb919f60c2104c547a1 245 Gene3D G3DSA:3.40.30.10 13 184 4.3E-10 T 29-03-2018 SMALA_RS40595 06b8482ac37e65f2d485d0fbf37b3641 477 SUPERFAMILY SSF75304 1 447 1.22E-105 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMALA_RS40595 06b8482ac37e65f2d485d0fbf37b3641 477 Pfam PF01425 Amidase 22 436 6.7E-75 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMALA_RS40595 06b8482ac37e65f2d485d0fbf37b3641 477 Gene3D G3DSA:3.90.1300.10 1 458 5.1E-109 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMALA_RS23985 81ab5fe3d2d6804c07f83674e33f320e 556 Pfam PF00474 Sodium:solute symporter family 44 453 1.6E-46 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 SMALA_RS23985 81ab5fe3d2d6804c07f83674e33f320e 556 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 44 453 3.1E-69 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 SMALA_RS11235 2f82b5bccefa68b993956165c2a1c8eb 122 Gene3D G3DSA:1.10.1660.10 25 118 1.1E-7 T 29-03-2018 SMALA_RS11235 2f82b5bccefa68b993956165c2a1c8eb 122 Pfam PF13591 MerR HTH family regulatory protein 31 110 1.5E-9 T 29-03-2018 SMALA_RS37585 5f0de09f8e67d37b9dca7e322d65be4f 366 Pfam PF01095 Pectinesterase 54 338 6.1E-43 T 29-03-2018 IPR000070 Pectinesterase, catalytic GO:0005618|GO:0030599|GO:0042545 KEGG: 00040+3.1.1.11|MetaCyc: PWY-1081|MetaCyc: PWY-7246|MetaCyc: PWY-7248 SMALA_RS37585 5f0de09f8e67d37b9dca7e322d65be4f 366 SUPERFAMILY SSF51126 48 361 1.48E-63 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor SMALA_RS37585 5f0de09f8e67d37b9dca7e322d65be4f 366 Gene3D G3DSA:2.160.20.10 46 366 7.9E-72 T 29-03-2018 IPR012334 Pectin lyase fold SMALA_RS28325 329551cc839440b167d24cbae9c67bc8 340 SUPERFAMILY SSF51556 6 334 3.37E-79 T 29-03-2018 IPR032466 Metal-dependent hydrolase SMALA_RS28325 329551cc839440b167d24cbae9c67bc8 340 Pfam PF00962 Adenosine/AMP deaminase 11 327 3.6E-91 T 29-03-2018 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 SMALA_RS28325 329551cc839440b167d24cbae9c67bc8 340 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 11 330 1.6E-83 T 29-03-2018 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 SMALA_RS28325 329551cc839440b167d24cbae9c67bc8 340 Gene3D G3DSA:3.20.20.140 6 334 1.1E-78 T 29-03-2018 SMALA_RS27025 7ec297f9e2df33aa57577455eed5a6f3 427 Pfam PF00005 ABC transporter 19 156 3.3E-23 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS27025 7ec297f9e2df33aa57577455eed5a6f3 427 SMART SM00382 26 204 2.9E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS27025 7ec297f9e2df33aa57577455eed5a6f3 427 Gene3D G3DSA:3.40.50.300 1 316 6.1E-54 T 29-03-2018 SMALA_RS27025 7ec297f9e2df33aa57577455eed5a6f3 427 SUPERFAMILY SSF52540 2 220 3.75E-53 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS04790 3cd1ba0e6b84e5519cfad399cca068db 354 Gene3D G3DSA:3.20.20.70 1 354 1.2E-112 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS04790 3cd1ba0e6b84e5519cfad399cca068db 354 SUPERFAMILY SSF51395 5 353 6.6E-107 T 29-03-2018 SMALA_RS04790 3cd1ba0e6b84e5519cfad399cca068db 354 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 5 329 2.9E-70 T 29-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 SMALA_RS17295 4015c27181299c9cab3335fb75e0fa9b 183 Pfam PF09534 Tryptophan-associated transmembrane protein (Trp_oprn_chp) 38 181 4.9E-6 T 29-03-2018 IPR019051 Trp biosynthesis associated, transmembrane protein, Oprn/Chp SMALA_RS19290 6be3cfca58979bcc743482a6a1f1c35c 248 Pfam PF07987 Domain of unkown function (DUF1775) 28 173 2.3E-54 T 29-03-2018 IPR012533 YcnI-like SMALA_RS19290 6be3cfca58979bcc743482a6a1f1c35c 248 Gene3D G3DSA:2.60.40.10 26 224 0.0013 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS11845 ad3b5c28c2961c312d5c13884ca896a8 137 Pfam PF13471 Transglutaminase-like superfamily 22 121 5.0E-14 T 29-03-2018 IPR032708 Microcin J25-processing protein McjB, C-terminal SMALA_RS02650 458bde8026093d7004e14d4dfd5951f9 318 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 311 3.5E-18 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS02650 458bde8026093d7004e14d4dfd5951f9 318 Gene3D G3DSA:1.10.3720.10 37 316 1.6E-49 T 29-03-2018 SMALA_RS02650 458bde8026093d7004e14d4dfd5951f9 318 SUPERFAMILY SSF161098 81 304 3.92E-58 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS20270 e73d4462d4a6fc9868015d699ccab602 491 Pfam PF08386 TAP-like protein 393 485 1.3E-26 T 29-03-2018 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal SMALA_RS20270 e73d4462d4a6fc9868015d699ccab602 491 SUPERFAMILY SSF53474 408 463 5.81E-25 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS20270 e73d4462d4a6fc9868015d699ccab602 491 SUPERFAMILY SSF53474 64 135 5.81E-25 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS20270 e73d4462d4a6fc9868015d699ccab602 491 SUPERFAMILY SSF53474 175 337 5.81E-25 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS20270 e73d4462d4a6fc9868015d699ccab602 491 Gene3D G3DSA:3.40.50.1820 30 478 1.6E-43 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS14660 3cee8ffffd549907f18889943dafb979 309 Gene3D G3DSA:3.40.50.1820 31 309 2.6E-33 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS14660 3cee8ffffd549907f18889943dafb979 309 SUPERFAMILY SSF53474 29 309 1.03E-39 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS14660 3cee8ffffd549907f18889943dafb979 309 Pfam PF12146 Serine aminopeptidase, S33 78 195 4.7E-8 T 29-03-2018 IPR022742 Serine aminopeptidase, S33 SMALA_RS31780 c01bac49b396a2b0281b9fd369c67a54 306 Pfam PF06386 Gas vesicle synthesis protein GvpL/GvpF 2 293 2.8E-54 T 29-03-2018 IPR009430 Gas vesicle protein GvpL/GvpF GO:0031411|GO:0031412 SMALA_RS18410 6bdf58a5f8df000bc92a835bd56a7a2d 166 Pfam PF00694 Aconitase C-terminal domain 38 104 1.6E-10 T 29-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS18410 6bdf58a5f8df000bc92a835bd56a7a2d 166 Gene3D G3DSA:3.20.19.10 2 162 8.4E-33 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel SMALA_RS18410 6bdf58a5f8df000bc92a835bd56a7a2d 166 TIGRFAM TIGR02087 LEUD_arch: 3-isopropylmalate dehydratase, small subunit 5 159 2.5E-42 T 29-03-2018 IPR011827 Hydrolyase LeuD/HacB/DmdB GO:0008152|GO:0016836 KEGG: 00290+4.2.1.33 SMALA_RS18410 6bdf58a5f8df000bc92a835bd56a7a2d 166 SUPERFAMILY SSF52016 4 160 1.1E-30 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel SMALA_RS15865 b4b68440bea400b0102c5b56002eb311 520 Gene3D G3DSA:2.60.290.11 158 274 3.8E-24 T 29-03-2018 SMALA_RS15865 b4b68440bea400b0102c5b56002eb311 520 Gene3D G3DSA:2.60.290.11 402 497 3.1E-10 T 29-03-2018 SMALA_RS15865 b4b68440bea400b0102c5b56002eb311 520 Gene3D G3DSA:2.60.290.11 275 401 2.1E-31 T 29-03-2018 SMALA_RS09030 a2671739c0e909868a1202d28326f3f9 539 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 46 461 5.8E-59 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 SMALA_RS09030 a2671739c0e909868a1202d28326f3f9 539 Pfam PF00474 Sodium:solute symporter family 46 462 1.8E-95 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 SMALA_RS10210 64256758dbf1693280c8a86912ac0012 265 Pfam PF08478 POTRA domain, FtsQ-type 63 131 2.2E-17 T 29-03-2018 IPR013685 POTRA domain, FtsQ-type SMALA_RS10210 64256758dbf1693280c8a86912ac0012 265 Pfam PF03799 Cell division protein FtsQ 135 245 3.6E-7 T 29-03-2018 IPR005548 Cell division protein FtsQ/DivIB SMALA_RS10210 64256758dbf1693280c8a86912ac0012 265 Hamap MF_00911 Cell division protein FtsQ [ftsQ]. 32 263 18.671 T 29-03-2018 IPR026579 Cell division protein FtsQ GO:0090529 SMALA_RS20490 bf0614ad50162b616f48ec3bf733f3e7 155 Pfam PF13673 Acetyltransferase (GNAT) domain 54 134 4.2E-10 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SMALA_RS20490 bf0614ad50162b616f48ec3bf733f3e7 155 SUPERFAMILY SSF55729 1 147 9.78E-24 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS20490 bf0614ad50162b616f48ec3bf733f3e7 155 Gene3D G3DSA:3.40.630.30 4 151 1.3E-21 T 29-03-2018 SMALA_RS13010 9a62ffc3b829a3a1cd42e3b0be17c0b2 180 Gene3D G3DSA:2.40.33.20 1 179 6.7E-43 T 29-03-2018 SMALA_RS13010 9a62ffc3b829a3a1cd42e3b0be17c0b2 180 SUPERFAMILY SSF50800 3 169 9.94E-40 T 29-03-2018 IPR011037 Pyruvate kinase-like, insert domain SMALA_RS13010 9a62ffc3b829a3a1cd42e3b0be17c0b2 180 Pfam PF03473 MOSC domain 57 165 1.6E-4 T 29-03-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 SMALA_RS35740 ca9b2e6ba357a815333c53825f7a025a 94 Pfam PF05402 Coenzyme PQQ synthesis protein D (PqqD) 37 93 2.6E-11 T 29-03-2018 IPR008792 Coenzyme PQQ synthesis D SMALA_RS35740 ca9b2e6ba357a815333c53825f7a025a 94 TIGRFAM TIGR03859 PQQ_PqqD: coenzyme PQQ biosynthesis protein PqqD 15 93 5.2E-21 T 29-03-2018 IPR022479 Coenzyme PQQ synthesis D, bacteria GO:0018189|GO:0048038 SMALA_RS21235 3fbb9067b392a3b936f27debd3d48a56 436 SUPERFAMILY SSF103473 12 405 6.67E-44 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS21235 3fbb9067b392a3b936f27debd3d48a56 436 Pfam PF07690 Major Facilitator Superfamily 15 249 1.6E-17 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS21235 3fbb9067b392a3b936f27debd3d48a56 436 Pfam PF07690 Major Facilitator Superfamily 251 404 1.4E-11 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS21235 3fbb9067b392a3b936f27debd3d48a56 436 Gene3D G3DSA:1.20.1250.20 207 412 1.6E-21 T 29-03-2018 SMALA_RS21235 3fbb9067b392a3b936f27debd3d48a56 436 Gene3D G3DSA:1.20.1250.20 7 194 2.3E-20 T 29-03-2018 SMALA_RS40445 af0ec0072d03a0cd56ed0303f0dfe1a6 292 Gene3D G3DSA:3.20.20.30 11 237 1.4E-48 T 29-03-2018 SMALA_RS40445 af0ec0072d03a0cd56ed0303f0dfe1a6 292 SUPERFAMILY SSF51679 9 273 1.44E-44 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS40445 af0ec0072d03a0cd56ed0303f0dfe1a6 292 Pfam PF00296 Luciferase-like monooxygenase 15 210 1.3E-36 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS20585 29cb233f8ddcb9c818146d17e2b0f244 359 Gene3D G3DSA:2.120.10.30 19 143 5.4E-6 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like SMALA_RS20585 29cb233f8ddcb9c818146d17e2b0f244 359 Gene3D G3DSA:2.120.10.30 144 340 1.3E-8 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like SMALA_RS20585 29cb233f8ddcb9c818146d17e2b0f244 359 SUPERFAMILY SSF63829 50 338 5.23E-20 T 29-03-2018 SMALA_RS18970 6cb503376d194ec0cd57817fc248de84 787 SUPERFAMILY SSF48576 1 321 1.73E-65 T 29-03-2018 IPR008949 Isoprenoid synthase domain SMALA_RS18970 6cb503376d194ec0cd57817fc248de84 787 SUPERFAMILY SSF48576 404 734 2.22E-59 T 29-03-2018 IPR008949 Isoprenoid synthase domain SMALA_RS18970 6cb503376d194ec0cd57817fc248de84 787 Gene3D G3DSA:1.10.600.10 407 751 3.1E-77 T 29-03-2018 IPR008949 Isoprenoid synthase domain SMALA_RS18970 6cb503376d194ec0cd57817fc248de84 787 Gene3D G3DSA:1.10.600.10 1 328 3.1E-79 T 29-03-2018 IPR008949 Isoprenoid synthase domain SMALA_RS37755 b70f2cd3acd2dcc2b21a682dedf8d9fd 695 TIGRFAM TIGR02243 TIGR02243: putative baseplate assembly protein 43 659 2.2E-65 T 29-03-2018 IPR011749 Conserved hypothetical protein CHP02243 SMALA_RS37755 b70f2cd3acd2dcc2b21a682dedf8d9fd 695 Pfam PF04865 Baseplate J-like protein 442 621 7.9E-10 T 29-03-2018 IPR006949 Baseplate protein J-like SMALA_RS28095 612e842f45a80c296b54ad4b22b85d0b 504 SUPERFAMILY SSF48452 419 456 1.41E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS28095 612e842f45a80c296b54ad4b22b85d0b 504 SUPERFAMILY SSF48452 240 357 1.41E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS28095 612e842f45a80c296b54ad4b22b85d0b 504 Gene3D G3DSA:1.25.40.10 91 494 1.9E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS15295 3eea0ec191209486b4eaa9fb2be50993 230 Pfam PF08892 YqcI/YcgG family 10 214 7.5E-55 T 29-03-2018 IPR014988 Uncharacterised protein family, YqcI/YcgG SMALA_RS04960 bc217683cf323a29bc24034c5aeb2cbc 316 Pfam PF09362 Domain of unknown function (DUF1996) 83 291 6.2E-52 T 29-03-2018 IPR018535 Domain of unknown function DUF1996 SMALA_RS42480 b19f51e3f87962e6c9a8ac6c26e000b0 137 SUPERFAMILY SSF46785 20 120 5.07E-34 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS42480 b19f51e3f87962e6c9a8ac6c26e000b0 137 Gene3D G3DSA:1.10.10.10 25 126 1.1E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS42480 b19f51e3f87962e6c9a8ac6c26e000b0 137 Pfam PF01638 HxlR-like helix-turn-helix 28 114 6.1E-31 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type SMALA_RS33500 fd16744c87182672db4dd9d049431e80 303 Pfam PF00975 Thioesterase domain 64 295 8.8E-17 T 29-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 SMALA_RS33500 fd16744c87182672db4dd9d049431e80 303 SUPERFAMILY SSF53474 4 296 7.22E-31 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS33500 fd16744c87182672db4dd9d049431e80 303 Gene3D G3DSA:3.40.50.1820 51 297 8.6E-22 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS34335 0d75205f9343e441c68ba3831f3972c3 363 Pfam PF11175 Protein of unknown function (DUF2961) 89 342 4.6E-84 T 29-03-2018 IPR021345 Protein of unknown function DUF2961 SMALA_RS02700 3491227de036617be7f44285afb22fb5 263 SUPERFAMILY SSF54637 147 259 1.4E-5 T 29-03-2018 IPR029069 HotDog domain SMALA_RS02700 3491227de036617be7f44285afb22fb5 263 Pfam PF13622 Thioesterase-like superfamily 23 257 3.1E-25 T 29-03-2018 SMALA_RS01665 29e457e9e89831f8afa1c64461e31869 214 SUPERFAMILY SSF102198 2 213 9.29E-55 T 29-03-2018 SMALA_RS01665 29e457e9e89831f8afa1c64461e31869 214 Pfam PF04199 Putative cyclase 4 150 8.6E-32 T 29-03-2018 IPR007325 Kynurenine formamidase GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 SMALA_RS01665 29e457e9e89831f8afa1c64461e31869 214 Gene3D G3DSA:3.50.30.50 1 214 7.3E-56 T 29-03-2018 SMALA_RS25130 3f160c9cb0c236f37d7b3daf50e9f5ef 283 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 68 275 3.7E-58 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 SMALA_RS25130 3f160c9cb0c236f37d7b3daf50e9f5ef 283 SUPERFAMILY SSF56529 55 276 1.96E-64 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 SMALA_RS25130 3f160c9cb0c236f37d7b3daf50e9f5ef 283 Gene3D G3DSA:3.90.850.10 36 278 1.6E-68 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 SMALA_RS06610 110b230d908a4d7636ccfbf729931875 389 Pfam PF00296 Luciferase-like monooxygenase 2 319 5.7E-41 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS06610 110b230d908a4d7636ccfbf729931875 389 Gene3D G3DSA:3.20.20.30 4 363 5.0E-64 T 29-03-2018 SMALA_RS06610 110b230d908a4d7636ccfbf729931875 389 SUPERFAMILY SSF51679 1 349 8.9E-67 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMALA_RS00740 e0f8b819b1cdb503ea23d4ebd1da3e05 312 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 45 303 9.8E-63 T 29-03-2018 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 SMALA_RS00740 e0f8b819b1cdb503ea23d4ebd1da3e05 312 SUPERFAMILY SSF51197 44 312 2.93E-89 T 29-03-2018 SMALA_RS00740 e0f8b819b1cdb503ea23d4ebd1da3e05 312 Gene3D G3DSA:3.60.130.10 40 312 3.9E-74 T 29-03-2018 SMALA_RS28615 41281e1080b3156d64a7f2cb2050613d 76 Pfam PF04149 Domain of unknown function (DUF397) 23 69 7.6E-10 T 29-03-2018 IPR007278 Domain of unknown function DUF397 SMALA_RS29275 a7bb5cfc57716d165b0e91af3d53de61 202 Gene3D G3DSA:3.40.50.300 14 198 6.4E-17 T 29-03-2018 SMALA_RS29275 a7bb5cfc57716d165b0e91af3d53de61 202 Pfam PF03029 Conserved hypothetical ATP binding protein 24 190 6.6E-21 T 29-03-2018 IPR004130 GPN-loop GTPase SMALA_RS29275 a7bb5cfc57716d165b0e91af3d53de61 202 SUPERFAMILY SSF52540 20 198 8.28E-19 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS36360 85200fd8945f7fb4a27ec397bc053215 384 Gene3D G3DSA:3.30.420.60 118 249 2.9E-16 T 29-03-2018 SMALA_RS23135 29d84772e5ff23d7e5125a12ee14b876 184 Gene3D G3DSA:2.60.120.430 53 180 8.7E-4 T 29-03-2018 SMALA_RS31170 184031b293c2e2773fe05f2a004dfa8e 403 Pfam PF02653 Branched-chain amino acid transport system / permease component 57 387 6.6E-34 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 SMALA_RS31170 184031b293c2e2773fe05f2a004dfa8e 403 Gene3D G3DSA:1.10.3470.10 59 393 4.5E-20 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SMALA_RS10375 ff910e81c3d514322173c97874cecb9b 172 Pfam PF14342 Domain of unknown function (DUF4396) 31 163 2.5E-41 T 29-03-2018 IPR025509 Domain of unknown function DUF4396 SMALA_RS34600 4b99a8af7663e02d539dc385244c7096 560 Pfam PF05960 Bacterial protein of unknown function (DUF885) 26 556 5.0E-153 T 29-03-2018 IPR010281 Protein of unknown function DUF885 SMALA_RS12730 a86164d6cf91ad774c3b7c3a876aef6f 379 SUPERFAMILY SSF103473 4 372 1.31E-48 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS12730 a86164d6cf91ad774c3b7c3a876aef6f 379 Gene3D G3DSA:1.20.1250.20 192 373 6.4E-15 T 29-03-2018 SMALA_RS12730 a86164d6cf91ad774c3b7c3a876aef6f 379 Gene3D G3DSA:1.20.1250.20 3 188 8.8E-25 T 29-03-2018 SMALA_RS12730 a86164d6cf91ad774c3b7c3a876aef6f 379 Pfam PF07690 Major Facilitator Superfamily 8 316 2.9E-31 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS38155 3385b5234510b919ec29d0f99efdaebf 208 Pfam PF01810 LysE type translocator 16 204 1.8E-34 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 SMALA_RS38155 3385b5234510b919ec29d0f99efdaebf 208 PIRSF PIRSF006324 1 208 4.7E-54 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 SMALA_RS15205 24c1f4009fdfb4cce5c07bc2e5b1be28 425 Gene3D G3DSA:1.10.150.130 75 161 9.6E-21 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal SMALA_RS15205 24c1f4009fdfb4cce5c07bc2e5b1be28 425 SUPERFAMILY SSF56349 271 394 2.38E-62 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 SMALA_RS15205 24c1f4009fdfb4cce5c07bc2e5b1be28 425 SUPERFAMILY SSF56349 75 236 2.38E-62 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 SMALA_RS15205 24c1f4009fdfb4cce5c07bc2e5b1be28 425 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 76 133 2.5E-7 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 SMALA_RS15205 24c1f4009fdfb4cce5c07bc2e5b1be28 425 Pfam PF00589 Phage integrase family 187 386 8.2E-20 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 SMALA_RS15205 24c1f4009fdfb4cce5c07bc2e5b1be28 425 Gene3D G3DSA:1.10.443.10 179 390 1.2E-43 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 SMALA_RS29450 950d6ca44d1bfd4e919cf659a2fb3cc4 169 Pfam PF07977 FabA-like domain 11 140 9.9E-14 T 29-03-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 SMALA_RS29450 950d6ca44d1bfd4e919cf659a2fb3cc4 169 Gene3D G3DSA:3.10.129.10 1 154 1.5E-35 T 29-03-2018 SMALA_RS29450 950d6ca44d1bfd4e919cf659a2fb3cc4 169 SUPERFAMILY SSF54637 1 148 5.79E-27 T 29-03-2018 IPR029069 HotDog domain SMALA_RS29795 029c4676efac93ccdba30d6987af677b 438 Pfam PF02653 Branched-chain amino acid transport system / permease component 102 422 5.0E-30 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 SMALA_RS29795 029c4676efac93ccdba30d6987af677b 438 Gene3D G3DSA:1.10.3470.10 95 430 2.2E-18 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SMALA_RS24725 21b3965a3cc0497c87f1866daa4da75e 72 Pfam PF04149 Domain of unknown function (DUF397) 12 65 3.3E-25 T 29-03-2018 IPR007278 Domain of unknown function DUF397 SMALA_RS17340 8f93501f53129af8d46bb17f044f8d60 301 Pfam PF11228 Protein of unknown function (DUF3027) 32 256 1.3E-81 T 29-03-2018 IPR021391 Protein of unknown function DUF3027 SMALA_RS42700 3e80cf4fe51aa1f7a61b4d088189abe5 518 Gene3D G3DSA:1.20.1250.20 296 497 1.2E-17 T 29-03-2018 SMALA_RS42700 3e80cf4fe51aa1f7a61b4d088189abe5 518 SUPERFAMILY SSF103473 67 486 6.8E-63 T 29-03-2018 IPR020846 Major facilitator superfamily domain SMALA_RS42700 3e80cf4fe51aa1f7a61b4d088189abe5 518 Pfam PF07690 Major Facilitator Superfamily 85 377 6.0E-27 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMALA_RS42700 3e80cf4fe51aa1f7a61b4d088189abe5 518 Gene3D G3DSA:1.20.1250.20 54 294 2.7E-25 T 29-03-2018 SMALA_RS23215 ff15ddcafad0f9a76bf51409813e1a25 219 SUPERFAMILY SSF53335 49 217 8.44E-34 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS23215 ff15ddcafad0f9a76bf51409813e1a25 219 Gene3D G3DSA:3.40.50.150 43 209 4.3E-27 T 29-03-2018 SMALA_RS23215 ff15ddcafad0f9a76bf51409813e1a25 219 Pfam PF13578 Methyltransferase domain 78 181 3.8E-18 T 29-03-2018 SMALA_RS01615 866bc56fa7913294f830538ade1e63f1 355 SUPERFAMILY SSF56801 65 306 4.19E-12 T 29-03-2018 SMALA_RS01615 866bc56fa7913294f830538ade1e63f1 355 Gene3D G3DSA:3.40.50.980 86 263 3.9E-12 T 29-03-2018 SMALA_RS23030 6c1a08deb6ac975b700c1c2288e8ce8d 185 Gene3D G3DSA:3.30.565.10 1 167 1.7E-10 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS34985 d52f6951a80b02f9da7d78e4bf61374c 222 Pfam PF01738 Dienelactone hydrolase family 87 212 5.7E-10 T 29-03-2018 IPR002925 Dienelactone hydrolase GO:0016787 SMALA_RS34985 d52f6951a80b02f9da7d78e4bf61374c 222 Gene3D G3DSA:3.40.50.1820 1 212 9.8E-30 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS34985 d52f6951a80b02f9da7d78e4bf61374c 222 SUPERFAMILY SSF53474 4 209 5.13E-34 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS09695 d5f61226103d4ad24130d3a733dccf03 154 Gene3D G3DSA:2.30.30.110 47 154 1.8E-17 T 29-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor SMALA_RS09695 d5f61226103d4ad24130d3a733dccf03 154 SUPERFAMILY SSF50118 47 149 2.4E-8 T 29-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor SMALA_RS09695 d5f61226103d4ad24130d3a733dccf03 154 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 50 147 1.4E-9 T 29-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 SMALA_RS21190 da90edb5488fd717faa64cf2426a69c9 546 Pfam PF13367 Protease prsW family 73 278 3.3E-53 T 29-03-2018 IPR026898 Protease PrsW GO:0008233 SMALA_RS16865 de4e7fb8b09bc546dc16156175d37902 218 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 18 210 8.1E-71 T 29-03-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 SMALA_RS16865 de4e7fb8b09bc546dc16156175d37902 218 SUPERFAMILY SSF53328 18 214 3.4E-60 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SMALA_RS16865 de4e7fb8b09bc546dc16156175d37902 218 Gene3D G3DSA:3.40.50.170 8 216 4.8E-68 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SMALA_RS16865 de4e7fb8b09bc546dc16156175d37902 218 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 18 206 29.963 T 29-03-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 SMALA_RS16865 de4e7fb8b09bc546dc16156175d37902 218 Pfam PF00551 Formyl transferase 18 200 1.4E-55 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SMALA_RS25860 0a79c52e445ac5c262d64a02cda14b12 181 Gene3D G3DSA:2.30.110.10 11 130 1.1E-5 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS30840 44e48683b6e3e405a8e99dec2a99cad5 292 Gene3D G3DSA:3.40.50.720 1 291 7.7E-22 T 29-03-2018 SMALA_RS30840 44e48683b6e3e405a8e99dec2a99cad5 292 SUPERFAMILY SSF51735 2 262 9.43E-46 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS30840 44e48683b6e3e405a8e99dec2a99cad5 292 Pfam PF13460 NAD(P)H-binding 6 144 4.9E-20 T 29-03-2018 IPR016040 NAD(P)-binding domain SMALA_RS06585 737fba0fcd917586c6f23c76850e8509 345 Gene3D G3DSA:3.20.20.140 11 336 3.2E-54 T 29-03-2018 SMALA_RS06585 737fba0fcd917586c6f23c76850e8509 345 Pfam PF04909 Amidohydrolase 53 335 9.4E-36 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 SMALA_RS06585 737fba0fcd917586c6f23c76850e8509 345 SUPERFAMILY SSF51556 49 336 4.76E-66 T 29-03-2018 IPR032466 Metal-dependent hydrolase SMALA_RS06245 0501edb557ae4ac1aa202fecb44db4a9 344 Gene3D G3DSA:3.40.50.1980 39 180 5.4E-22 T 29-03-2018 SMALA_RS06245 0501edb557ae4ac1aa202fecb44db4a9 344 Pfam PF01497 Periplasmic binding protein 72 318 1.6E-23 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 SMALA_RS06245 0501edb557ae4ac1aa202fecb44db4a9 344 Gene3D G3DSA:3.40.50.1980 181 344 3.8E-31 T 29-03-2018 SMALA_RS06245 0501edb557ae4ac1aa202fecb44db4a9 344 SUPERFAMILY SSF53807 48 344 7.46E-38 T 29-03-2018 SMALA_RS00260 185428dbbc08b7422635aaf85c678e3e 410 Pfam PF01757 Acyltransferase family 25 370 3.3E-26 T 29-03-2018 IPR002656 Acyltransferase 3 GO:0016747 SMALA_RS08070 9355cd0b2d9269c668a5fbb5e7344e37 280 Pfam PF13349 Putative adhesin 21 276 5.5E-11 T 29-03-2018 IPR025164 Putative adhesin SMALA_RS14550 a59deb9060e7475c6473210938f3ab08 422 TIGRFAM TIGR03296 M6dom_TIGR03296: M6 family metalloprotease domain 79 348 2.0E-52 T 29-03-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 SMALA_RS39025 40b22323b6f450ee44570c1b5562c83b 269 Pfam PF00005 ABC transporter 28 186 7.5E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMALA_RS39025 40b22323b6f450ee44570c1b5562c83b 269 SMART SM00382 36 236 4.7E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain SMALA_RS39025 40b22323b6f450ee44570c1b5562c83b 269 Gene3D G3DSA:3.40.50.300 4 269 4.7E-72 T 29-03-2018 SMALA_RS39025 40b22323b6f450ee44570c1b5562c83b 269 SUPERFAMILY SSF52540 7 258 1.01E-65 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS22215 50b78472d3951681cf6f950c7725a44b 295 Pfam PF12679 ABC-2 family transporter protein 20 292 1.9E-12 T 29-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 SMALA_RS35725 b21ff82fe80d302d44f93f23372d9d01 47 TIGRFAM TIGR02107 PQQ_syn_pqqA: coenzyme PQQ precursor peptide PqqA 25 45 7.2E-6 T 29-03-2018 IPR011725 Coenzyme PQQ biosynthesis protein A GO:0018189 SMALA_RS18555 7252453d2a8248a1a14bfe3bf55da997 311 Pfam PF00482 Type II secretion system (T2SS), protein F 139 255 5.9E-8 T 29-03-2018 IPR018076 Type II secretion system F domain SMALA_RS10710 fb053724519fb1db600ed63916ee151a 538 Gene3D G3DSA:1.25.40.10 141 509 5.1E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS13550 b5b6804d8dfff318039eb258808dd153 117 Pfam PF14525 AraC-binding-like domain 6 105 2.9E-13 T 29-03-2018 IPR035418 Transcription regulator HTH, AraC- type, ligand binding domain-like SMALA_RS17920 5b95ab59e3744451a012343ee6311157 69 Pfam PF04149 Domain of unknown function (DUF397) 6 57 9.1E-11 T 29-03-2018 IPR007278 Domain of unknown function DUF397 SMALA_RS21675 ffbc67481db2f4fdcb66f748710bf97b 569 Gene3D G3DSA:2.60.40.10 451 546 2.3E-5 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS21675 ffbc67481db2f4fdcb66f748710bf97b 569 Gene3D G3DSA:1.10.1740.10 15 109 2.2E-4 T 29-03-2018 SMALA_RS08160 7f784d7b30afb31c7439ea9873a39e73 203 Gene3D G3DSA:2.20.25.10 137 186 0.0012 T 29-03-2018 SMALA_RS36005 5f0f4728c5042d7b35e8b8738c6f488b 245 Pfam PF01061 ABC-2 type transporter 9 212 1.4E-24 T 29-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 SMALA_RS36005 5f0f4728c5042d7b35e8b8738c6f488b 245 PIRSF PIRSF006648 3 245 4.4E-25 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMALA_RS36005 5f0f4728c5042d7b35e8b8738c6f488b 245 PRINTS PR00164 ABC-2 type transport system membrane protein signature 172 191 8.6E-5 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMALA_RS36005 5f0f4728c5042d7b35e8b8738c6f488b 245 PRINTS PR00164 ABC-2 type transport system membrane protein signature 135 159 8.6E-5 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMALA_RS08120 3aef113202a2a7075eb839ad87ee480f 340 Pfam PF01636 Phosphotransferase enzyme family 34 250 6.5E-49 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase SMALA_RS08120 3aef113202a2a7075eb839ad87ee480f 340 SUPERFAMILY SSF56112 7 313 6.96E-64 T 29-03-2018 IPR011009 Protein kinase-like domain SMALA_RS08120 3aef113202a2a7075eb839ad87ee480f 340 Gene3D G3DSA:3.30.200.20 8 109 7.3E-31 T 29-03-2018 SMALA_RS08120 3aef113202a2a7075eb839ad87ee480f 340 Gene3D G3DSA:3.90.1200.10 110 297 3.4E-32 T 29-03-2018 SMALA_RS40800 f8ab5be6f50487b89438e7de87da4492 383 Gene3D G3DSA:3.40.190.10 256 382 1.9E-13 T 29-03-2018 SMALA_RS40800 f8ab5be6f50487b89438e7de87da4492 383 SUPERFAMILY SSF53850 138 367 1.86E-47 T 29-03-2018 SMALA_RS40800 f8ab5be6f50487b89438e7de87da4492 383 SMART SM00062 140 371 5.5E-39 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SMALA_RS40800 f8ab5be6f50487b89438e7de87da4492 383 Gene3D G3DSA:3.40.190.10 78 255 6.0E-27 T 29-03-2018 SMALA_RS40800 f8ab5be6f50487b89438e7de87da4492 383 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 141 366 8.6E-46 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SMALA_RS03155 02e7de833cb9cbf44ba45b40fd446008 235 Pfam PF00857 Isochorismatase family 30 208 3.1E-36 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SMALA_RS03155 02e7de833cb9cbf44ba45b40fd446008 235 SUPERFAMILY SSF52499 16 213 4.45E-46 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SMALA_RS03155 02e7de833cb9cbf44ba45b40fd446008 235 Gene3D G3DSA:3.40.50.850 8 218 3.2E-41 T 29-03-2018 SMALA_RS33995 c4e2aebb77032d43b3ca46460dfac01c 276 SUPERFAMILY SSF161098 69 253 6.28E-33 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS33995 c4e2aebb77032d43b3ca46460dfac01c 276 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 94 264 2.7E-22 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS33995 c4e2aebb77032d43b3ca46460dfac01c 276 Gene3D G3DSA:1.10.3720.10 24 269 3.9E-30 T 29-03-2018 SMALA_RS32835 e7295374c84ec15c4f0775d322ed4097 123 Gene3D G3DSA:3.10.180.10 3 121 1.1E-17 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS32835 e7295374c84ec15c4f0775d322ed4097 123 SUPERFAMILY SSF54593 9 120 1.48E-16 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS15225 c5203e79b5c23c9f24ad77a5048d9eb0 292 SMART SM00943 11 180 8.0E-31 T 29-03-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal SMALA_RS15225 c5203e79b5c23c9f24ad77a5048d9eb0 292 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 11 154 1.2E-8 T 29-03-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal SMALA_RS25655 6f249761b633f05f3f3595c193e79aa9 234 Gene3D G3DSA:3.40.630.30 82 234 8.9E-16 T 29-03-2018 SMALA_RS25655 6f249761b633f05f3f3595c193e79aa9 234 Pfam PF00583 Acetyltransferase (GNAT) family 125 222 1.8E-6 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SMALA_RS25655 6f249761b633f05f3f3595c193e79aa9 234 SUPERFAMILY SSF55729 33 229 9.19E-16 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS04000 0325474f9e8b9314c89f53394b3b7926 418 SUPERFAMILY SSF53850 24 415 1.24E-59 T 29-03-2018 SMALA_RS04000 0325474f9e8b9314c89f53394b3b7926 418 Gene3D G3DSA:3.40.190.10 24 211 3.5E-29 T 29-03-2018 SMALA_RS04000 0325474f9e8b9314c89f53394b3b7926 418 Pfam PF01547 Bacterial extracellular solute-binding protein 46 330 1.7E-30 T 29-03-2018 IPR006059 Solute-binding family 1 GO:0006810 SMALA_RS04000 0325474f9e8b9314c89f53394b3b7926 418 Gene3D G3DSA:3.40.190.10 228 372 2.2E-6 T 29-03-2018 SMALA_RS18815 e2101d03fa730b723051e9e6f582699d 271 Pfam PF01148 Cytidylyltransferase family 30 266 7.5E-30 T 29-03-2018 SMALA_RS17925 440b04b53b0faa45673105e286d3101d 101 Pfam PF04149 Domain of unknown function (DUF397) 21 39 6.9E-5 T 29-03-2018 IPR007278 Domain of unknown function DUF397 SMALA_RS17925 440b04b53b0faa45673105e286d3101d 101 Pfam PF04149 Domain of unknown function (DUF397) 41 91 3.1E-14 T 29-03-2018 IPR007278 Domain of unknown function DUF397 SMALA_RS17925 440b04b53b0faa45673105e286d3101d 101 Pfam PF04149 Domain of unknown function (DUF397) 3 20 6.9E-5 T 29-03-2018 IPR007278 Domain of unknown function DUF397 SMALA_RS32030 111c37f7027f780f06fa622c91cb40f9 307 Pfam PF01545 Cation efflux family 22 213 2.2E-46 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 SMALA_RS32030 111c37f7027f780f06fa622c91cb40f9 307 Gene3D G3DSA:1.20.1510.10 18 213 6.1E-58 T 29-03-2018 SMALA_RS32030 111c37f7027f780f06fa622c91cb40f9 307 Gene3D G3DSA:3.30.70.1350 214 298 2.7E-17 T 29-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain SMALA_RS32030 111c37f7027f780f06fa622c91cb40f9 307 SUPERFAMILY SSF161111 18 214 1.07E-53 T 29-03-2018 SMALA_RS32030 111c37f7027f780f06fa622c91cb40f9 307 SUPERFAMILY SSF160240 216 295 3.4E-12 T 29-03-2018 SMALA_RS32030 111c37f7027f780f06fa622c91cb40f9 307 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 21 296 3.8E-91 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 SMALA_RS39305 616da9bf91e27041c0277245320b3d82 268 Gene3D G3DSA:3.40.50.1820 6 268 5.8E-33 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS39305 616da9bf91e27041c0277245320b3d82 268 Pfam PF12697 Alpha/beta hydrolase family 30 252 1.2E-16 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 SMALA_RS39305 616da9bf91e27041c0277245320b3d82 268 SUPERFAMILY SSF53474 12 257 1.46E-37 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS10390 740fe296857f3a5ef5e2194c394d8f64 86 Pfam PF04324 BFD-like [2Fe-2S] binding domain 2 50 7.5E-11 T 29-03-2018 IPR007419 BFD-like [2Fe-2S]-binding domain SMALA_RS04355 bd18e5250dfc472363f1a2c5a2a76bd2 257 Gene3D G3DSA:3.30.2140.10 1 158 1.1E-35 T 29-03-2018 SMALA_RS04355 bd18e5250dfc472363f1a2c5a2a76bd2 257 Pfam PF00797 N-acetyltransferase 20 250 2.2E-46 T 29-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 SMALA_RS04355 bd18e5250dfc472363f1a2c5a2a76bd2 257 SUPERFAMILY SSF54001 1 249 1.1E-62 T 29-03-2018 SMALA_RS21335 2f64df4f150d9675d202a686f9715240 206 Pfam PF01865 Protein of unknown function DUF47 7 203 3.1E-30 T 29-03-2018 IPR018445 Putative phosphate transport regulator SMALA_RS21335 2f64df4f150d9675d202a686f9715240 206 Gene3D G3DSA:1.20.58.220 101 205 8.2E-7 T 29-03-2018 SMALA_RS21335 2f64df4f150d9675d202a686f9715240 206 SUPERFAMILY SSF109755 41 199 5.1E-5 T 29-03-2018 SMALA_RS11920 3aa8895e8ae5dc314d56cc909c06486a 396 Pfam PF04332 Protein of unknown function (DUF475) 44 379 4.8E-131 T 29-03-2018 IPR007427 Protein of unknown function DUF475 SMALA_RS28120 df8fee8b64d3afee3e691c7a04649f6d 269 Gene3D G3DSA:3.40.50.150 4 268 3.1E-17 T 29-03-2018 SMALA_RS28120 df8fee8b64d3afee3e691c7a04649f6d 269 SUPERFAMILY SSF53335 5 218 9.38E-16 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS20720 4ff194e42c70d52403ed47a5dff996f1 126 Gene3D G3DSA:3.10.180.10 1 126 3.5E-16 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS20720 4ff194e42c70d52403ed47a5dff996f1 126 SUPERFAMILY SSF54593 18 109 3.95E-9 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMALA_RS16550 89f3ab826fbcafd079164bb3d4b6a2d6 453 SUPERFAMILY SSF53756 76 312 8.63E-8 T 29-03-2018 SMALA_RS16550 89f3ab826fbcafd079164bb3d4b6a2d6 453 Gene3D G3DSA:3.40.50.720 92 321 0.0039 T 29-03-2018 SMALA_RS00250 049f5aa34e66531187d799e142e30a34 346 Pfam PF00248 Aldo/keto reductase family 17 310 8.7E-75 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS00250 049f5aa34e66531187d799e142e30a34 346 SUPERFAMILY SSF51430 2 311 4.32E-99 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS00250 049f5aa34e66531187d799e142e30a34 346 Gene3D G3DSA:3.20.20.100 3 312 1.3E-93 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS00250 049f5aa34e66531187d799e142e30a34 346 PRINTS PR00069 Aldo-keto reductase signature 137 154 9.7E-11 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMALA_RS00250 049f5aa34e66531187d799e142e30a34 346 PRINTS PR00069 Aldo-keto reductase signature 41 65 9.7E-11 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMALA_RS00250 049f5aa34e66531187d799e142e30a34 346 PRINTS PR00069 Aldo-keto reductase signature 106 124 9.7E-11 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMALA_RS11810 500646bfca49ec2f0c4911afe7479ec3 231 Gene3D G3DSA:3.40.50.360 32 220 8.0E-31 T 29-03-2018 IPR029039 Flavoprotein-like domain SMALA_RS11810 500646bfca49ec2f0c4911afe7479ec3 231 Pfam PF03358 NADPH-dependent FMN reductase 38 188 7.1E-32 T 29-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 SMALA_RS11810 500646bfca49ec2f0c4911afe7479ec3 231 SUPERFAMILY SSF52218 39 214 4.41E-34 T 29-03-2018 IPR029039 Flavoprotein-like domain SMALA_RS26685 3ab7d6bd53db6873da5c9c66ec119984 124 Gene3D G3DSA:1.10.10.10 1 113 4.0E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS26685 3ab7d6bd53db6873da5c9c66ec119984 124 PRINTS PR00598 Bacterial regulatory protein MarR family signature 18 34 4.0E-5 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS26685 3ab7d6bd53db6873da5c9c66ec119984 124 PRINTS PR00598 Bacterial regulatory protein MarR family signature 35 50 4.0E-5 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS26685 3ab7d6bd53db6873da5c9c66ec119984 124 PRINTS PR00598 Bacterial regulatory protein MarR family signature 54 70 4.0E-5 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS26685 3ab7d6bd53db6873da5c9c66ec119984 124 PRINTS PR00598 Bacterial regulatory protein MarR family signature 84 104 4.0E-5 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS26685 3ab7d6bd53db6873da5c9c66ec119984 124 SMART SM00347 1 94 1.4E-7 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS26685 3ab7d6bd53db6873da5c9c66ec119984 124 Pfam PF01047 MarR family 6 54 4.5E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMALA_RS26685 3ab7d6bd53db6873da5c9c66ec119984 124 SUPERFAMILY SSF46785 2 107 3.86E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS09090 c207f262d83612fc0c683a18044a05e1 184 Gene3D G3DSA:1.20.1250.20 2 88 1.3E-4 T 29-03-2018 SMALA_RS25980 6371b532610d00e6615cc559b945d16e 502 SUPERFAMILY SSF53474 84 145 1.54E-24 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS25980 6371b532610d00e6615cc559b945d16e 502 SUPERFAMILY SSF53474 188 463 1.54E-24 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS25980 6371b532610d00e6615cc559b945d16e 502 Gene3D G3DSA:3.40.50.1820 29 492 2.4E-40 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS25980 6371b532610d00e6615cc559b945d16e 502 Pfam PF08386 TAP-like protein 397 501 1.5E-30 T 29-03-2018 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal SMALA_RS24840 6e944651fa6c45d9ecf5fa4c4064b847 239 Gene3D G3DSA:3.40.50.150 23 212 5.2E-31 T 29-03-2018 SMALA_RS24840 6e944651fa6c45d9ecf5fa4c4064b847 239 SUPERFAMILY SSF53335 28 213 2.25E-32 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS24840 6e944651fa6c45d9ecf5fa4c4064b847 239 Pfam PF13649 Methyltransferase domain 65 166 4.5E-15 T 29-03-2018 SMALA_RS01400 be8111979bbd3755a57f8a853bba7d94 453 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 172 187 2.9E-5 T 29-03-2018 SMALA_RS01400 be8111979bbd3755a57f8a853bba7d94 453 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 312 327 2.9E-5 T 29-03-2018 SMALA_RS01400 be8111979bbd3755a57f8a853bba7d94 453 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 327 343 2.9E-5 T 29-03-2018 SMALA_RS01400 be8111979bbd3755a57f8a853bba7d94 453 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 12 34 2.9E-5 T 29-03-2018 SMALA_RS01400 be8111979bbd3755a57f8a853bba7d94 453 Pfam PF01494 FAD binding domain 13 338 6.0E-5 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 SMALA_RS01400 be8111979bbd3755a57f8a853bba7d94 453 Gene3D G3DSA:3.50.50.60 12 347 2.8E-24 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS01400 be8111979bbd3755a57f8a853bba7d94 453 SUPERFAMILY SSF51905 394 439 2.28E-25 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS01400 be8111979bbd3755a57f8a853bba7d94 453 SUPERFAMILY SSF51905 308 354 2.28E-25 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS01400 be8111979bbd3755a57f8a853bba7d94 453 SUPERFAMILY SSF51905 13 197 2.28E-25 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS10735 ba1e313977674819a246393cb0ca3c67 155 Pfam PF06271 RDD family 43 148 9.2E-10 T 29-03-2018 IPR010432 RDD SMALA_RS10735 ba1e313977674819a246393cb0ca3c67 155 PIRSF PIRSF021697 3 155 6.0E-46 T 29-03-2018 IPR016795 Uncharacterised conserved protein UCP021697, membrane SMALA_RS36400 8809e86ea7067a2a9d0208d76769fea4 306 Pfam PF03547 Membrane transport protein 159 298 4.7E-12 T 29-03-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 SMALA_RS36400 8809e86ea7067a2a9d0208d76769fea4 306 Pfam PF03547 Membrane transport protein 13 133 4.8E-9 T 29-03-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 SMALA_RS36095 96f9a2113f55556aa58cbec27ceff8ec 256 Gene3D G3DSA:1.20.1630.10 132 234 0.016 T 29-03-2018 SMALA_RS36095 96f9a2113f55556aa58cbec27ceff8ec 256 Pfam PF14023 Protein of unknown function (DUF4239) 48 234 2.9E-17 T 29-03-2018 IPR025333 Protein of unknown function DUF4239 SMALA_RS14840 8ab9fc45342857db08a7d68dadc8fb25 154 Gene3D G3DSA:1.10.287.70 7 50 0.032 T 29-03-2018 SMALA_RS14815 5750b90cd7cdd2fd69a51362ddfbbf04 69 Pfam PF04149 Domain of unknown function (DUF397) 13 63 1.5E-15 T 29-03-2018 IPR007278 Domain of unknown function DUF397 SMALA_RS41175 fca26693557dd20aafc27e5ff8d75e27 336 TIGRFAM TIGR03769 P_ac_wall_RPT: actinobacterial surface-anchored protein domain 191 230 7.9E-15 T 29-03-2018 IPR022435 Surface-anchored repeat, actinobacteria SMALA_RS37695 8a28bebbb767026a02300065a3c39d22 192 Pfam PF14065 Protein of unknown function (DUF4255) 9 181 1.4E-38 T 29-03-2018 IPR025351 Protein of unknown function DUF4255 SMALA_RS29205 ba05c7e724d4e919869eca5c18aac2c7 148 Pfam PF11292 Protein of unknown function (DUF3093) 4 142 1.5E-44 T 29-03-2018 IPR021443 Protein of unknown function DUF3093 SMALA_RS20180 c3176bbf03de35bf55d62bc9dcae3a20 314 TIGRFAM TIGR02778 ligD_pol: DNA ligase D, polymerase domain 18 264 1.5E-68 T 29-03-2018 IPR014145 DNA ligase D, polymerase domain SMALA_RS04965 3c6f071c0cfdd449e3d52502eba787ec 219 Gene3D G3DSA:1.20.1260.10 62 204 2.2E-24 T 29-03-2018 IPR012347 Ferritin-related SMALA_RS04965 3c6f071c0cfdd449e3d52502eba787ec 219 Pfam PF03713 Domain of unknown function (DUF305) 74 202 3.7E-17 T 29-03-2018 IPR005183 Domain of unknown function DUF305 SMALA_RS28600 101ffa377359ddeb959c65968f964dbd 142 Gene3D G3DSA:1.10.287.1060 35 134 2.0E-13 T 29-03-2018 SMALA_RS38490 82653abbc035a8688f4786d0093dc1ad 305 Pfam PF01040 UbiA prenyltransferase family 52 276 2.3E-12 T 29-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 SMALA_RS05980 a054c208b898e8308779a3b5d36d735c 279 Pfam PF03988 Repeat of Unknown Function (DUF347) 37 85 2.8E-15 T 29-03-2018 IPR007136 Protein of unknown function DUF347 SMALA_RS05980 a054c208b898e8308779a3b5d36d735c 279 Pfam PF03988 Repeat of Unknown Function (DUF347) 212 266 3.7E-17 T 29-03-2018 IPR007136 Protein of unknown function DUF347 SMALA_RS05980 a054c208b898e8308779a3b5d36d735c 279 Pfam PF03988 Repeat of Unknown Function (DUF347) 156 203 5.9E-12 T 29-03-2018 IPR007136 Protein of unknown function DUF347 SMALA_RS05980 a054c208b898e8308779a3b5d36d735c 279 Pfam PF03988 Repeat of Unknown Function (DUF347) 91 142 1.6E-12 T 29-03-2018 IPR007136 Protein of unknown function DUF347 SMALA_RS06290 92471de490198a927884509037b18373 223 SUPERFAMILY SSF53955 68 214 1.88E-8 T 29-03-2018 IPR023346 Lysozyme-like domain SMALA_RS06290 92471de490198a927884509037b18373 223 Gene3D G3DSA:1.10.530.10 58 221 9.2E-12 T 29-03-2018 SMALA_RS39165 b34c20f0e98bc44442963998290775e1 450 Gene3D G3DSA:3.90.226.10 147 448 3.0E-35 T 29-03-2018 SMALA_RS39165 b34c20f0e98bc44442963998290775e1 450 Pfam PF00378 Enoyl-CoA hydratase/isomerase 284 390 8.6E-15 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 SMALA_RS39165 b34c20f0e98bc44442963998290775e1 450 SUPERFAMILY SSF52096 167 439 2.38E-34 T 29-03-2018 IPR029045 ClpP/crotonase-like domain SMALA_RS40425 c7db14361b410b51f8f7d0218a55c0f8 333 Pfam PF02653 Branched-chain amino acid transport system / permease component 59 323 6.9E-40 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 SMALA_RS40425 c7db14361b410b51f8f7d0218a55c0f8 333 Gene3D G3DSA:1.10.3470.10 25 333 3.7E-27 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SMALA_RS27925 5686d657521b87f85d72a859f1669e5c 197 Gene3D G3DSA:3.20.19.10 1 168 2.6E-49 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel SMALA_RS27925 5686d657521b87f85d72a859f1669e5c 197 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 191 39.947 T 29-03-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 SMALA_RS27925 5686d657521b87f85d72a859f1669e5c 197 SUPERFAMILY SSF52016 1 188 7.06E-54 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel SMALA_RS27925 5686d657521b87f85d72a859f1669e5c 197 Pfam PF00694 Aconitase C-terminal domain 1 117 1.6E-25 T 29-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 SMALA_RS27925 5686d657521b87f85d72a859f1669e5c 197 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 180 1.3E-55 T 29-03-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 SMALA_RS23240 e6f1fcc8b330798109790274373f6399 431 Pfam PF09594 Glycosyltransferase family 87 33 303 3.8E-46 T 29-03-2018 IPR018584 Glycosyltransferase family 87 GO:0016758 SMALA_RS35485 50fdc79007ba9b039e56650ae058485e 461 SUPERFAMILY SSF53850 42 447 6.14E-69 T 29-03-2018 SMALA_RS35485 50fdc79007ba9b039e56650ae058485e 461 Pfam PF01547 Bacterial extracellular solute-binding protein 62 355 2.0E-37 T 29-03-2018 IPR006059 Solute-binding family 1 GO:0006810 SMALA_RS35485 50fdc79007ba9b039e56650ae058485e 461 Gene3D G3DSA:3.40.190.10 44 183 1.2E-20 T 29-03-2018 SMALA_RS35485 50fdc79007ba9b039e56650ae058485e 461 Gene3D G3DSA:3.40.190.10 184 446 5.4E-38 T 29-03-2018 SMALA_RS20975 9b0330e5ace7b4493cbe74de50be43fd 363 Pfam PF06626 Protein of unknown function (DUF1152) 4 289 1.1E-87 T 29-03-2018 IPR010581 Protein of unknown function DUF1152 SMALA_RS07170 ffe22d0842f171fad5db148e7b2af857 293 Gene3D G3DSA:2.40.30.10 5 131 9.9E-36 T 29-03-2018 SMALA_RS07170 ffe22d0842f171fad5db148e7b2af857 293 SUPERFAMILY SSF63380 8 135 4.12E-15 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 SMALA_RS07170 ffe22d0842f171fad5db148e7b2af857 293 Gene3D G3DSA:3.40.50.80 133 284 1.2E-46 T 29-03-2018 SMALA_RS07170 ffe22d0842f171fad5db148e7b2af857 293 Pfam PF04954 Siderophore-interacting protein 138 262 4.0E-36 T 29-03-2018 IPR007037 Siderophore-interacting protein SMALA_RS07170 ffe22d0842f171fad5db148e7b2af857 293 Pfam PF08021 Siderophore-interacting FAD-binding domain 16 131 5.5E-39 T 29-03-2018 IPR013113 FAD-binding 9, siderophore-interacting SMALA_RS19100 32bdd85816eba8abb7bc776d64463339 815 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 150 308 9.1E-31 T 29-03-2018 SMALA_RS26655 7d3a34059db2a27367024a05d525921f 372 Pfam PF11583 P-aminobenzoate N-oxygenase AurF 34 305 6.6E-14 T 29-03-2018 IPR025859 P-aminobenzoate N-oxygenase AurF SMALA_RS26655 7d3a34059db2a27367024a05d525921f 372 Gene3D G3DSA:1.10.620.20 17 296 9.3E-57 T 29-03-2018 SMALA_RS26655 7d3a34059db2a27367024a05d525921f 372 SUPERFAMILY SSF47240 89 318 5.86E-66 T 29-03-2018 IPR009078 Ferritin-like superfamily SMALA_RS13310 d7b8e7b9f70e1abb7a43f6d7ed167220 204 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 54 196 5.0E-24 T 29-03-2018 IPR009936 Protein of unknown function DUF1468 SMALA_RS26650 83b14f3aabe1e1c89b1d9a278e474a77 316 Gene3D G3DSA:1.10.620.20 9 284 3.6E-33 T 29-03-2018 SMALA_RS26650 83b14f3aabe1e1c89b1d9a278e474a77 316 Pfam PF11583 P-aminobenzoate N-oxygenase AurF 25 299 4.8E-100 T 29-03-2018 IPR025859 P-aminobenzoate N-oxygenase AurF SMALA_RS26650 83b14f3aabe1e1c89b1d9a278e474a77 316 SUPERFAMILY SSF47240 42 229 1.41E-10 T 29-03-2018 IPR009078 Ferritin-like superfamily SMALA_RS07435 f531de5f63eb6588d62498d697c10905 268 SUPERFAMILY SSF47240 17 170 5.55E-9 T 29-03-2018 IPR009078 Ferritin-like superfamily SMALA_RS07435 f531de5f63eb6588d62498d697c10905 268 Gene3D G3DSA:1.20.1260.10 13 251 1.4E-19 T 29-03-2018 IPR012347 Ferritin-related SMALA_RS42885 395a670e1f60b5a8b95dc6e9b35f6be0 246 Gene3D G3DSA:3.40.50.1820 1 246 3.5E-20 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS42885 395a670e1f60b5a8b95dc6e9b35f6be0 246 SUPERFAMILY SSF53474 127 246 2.21E-15 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS42885 395a670e1f60b5a8b95dc6e9b35f6be0 246 SUPERFAMILY SSF53474 22 89 2.21E-15 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SMALA_RS39445 7745e5eb2aede59328a33a07b03c7429 159 Gene3D G3DSA:3.40.50.300 2 149 8.5E-5 T 29-03-2018 SMALA_RS37130 027fde3fd1613ed7d12dcb4726ec9a85 447 Gene3D G3DSA:2.60.40.10 13 98 1.9E-5 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS37130 027fde3fd1613ed7d12dcb4726ec9a85 447 Gene3D G3DSA:2.60.40.10 100 203 1.2E-5 T 29-03-2018 IPR013783 Immunoglobulin-like fold SMALA_RS15915 e13c862833cfe739646456a607869487 372 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 98 253 2.1E-47 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain SMALA_RS15915 e13c862833cfe739646456a607869487 372 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 98 253 9.9E-47 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain SMALA_RS20625 f4dd9f0d3ba8a008737fe3d35e885cf1 317 Pfam PF04893 Yip1 domain 152 308 4.1E-12 T 29-03-2018 IPR006977 Yip1 domain GO:0016020 SMALA_RS30875 20e00dfa63693ad198febf41d267329a 168 Gene3D G3DSA:3.10.129.10 1 150 3.3E-31 T 29-03-2018 SMALA_RS30875 20e00dfa63693ad198febf41d267329a 168 SUPERFAMILY SSF54637 2 148 8.3E-44 T 29-03-2018 IPR029069 HotDog domain SMALA_RS30875 20e00dfa63693ad198febf41d267329a 168 Pfam PF01575 MaoC like domain 12 126 2.2E-16 T 29-03-2018 IPR002539 MaoC-like domain SMALA_RS12020 886e24f1b79a83347f4e2e0fc4260e32 394 Pfam PF13556 PucR C-terminal helix-turn-helix domain 326 383 6.9E-20 T 29-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain SMALA_RS12020 886e24f1b79a83347f4e2e0fc4260e32 394 Gene3D G3DSA:1.10.10.60 308 362 1.4E-4 T 29-03-2018 SMALA_RS33625 46cc30faf092d1aa1487dcfac823ac7f 176 SUPERFAMILY SSF52540 3 168 1.45E-15 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS33625 46cc30faf092d1aa1487dcfac823ac7f 176 Gene3D G3DSA:3.40.50.300 3 174 5.6E-15 T 29-03-2018 SMALA_RS18820 f47a7b0e3f4d8149f045ce7f0f2066bb 224 Pfam PF01066 CDP-alcohol phosphatidyltransferase 28 95 4.1E-9 T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 SMALA_RS19455 b14d6824ed876094c74549ac87022903 483 Pfam PF07907 YibE/F-like protein 194 431 1.9E-70 T 29-03-2018 IPR012507 YibE/F-like SMALA_RS33815 977a0dd5a6ec4c46e47e9bcae007e71d 250 Pfam PF02754 Cysteine-rich domain 138 222 5.1E-16 T 29-03-2018 IPR004017 Cysteine-rich domain SMALA_RS33815 977a0dd5a6ec4c46e47e9bcae007e71d 250 Pfam PF02754 Cysteine-rich domain 3 83 4.1E-14 T 29-03-2018 IPR004017 Cysteine-rich domain SMALA_RS33895 5530c3e9cae7fa97d5c0240194f4055d 70 Pfam PF04149 Domain of unknown function (DUF397) 14 68 7.6E-22 T 29-03-2018 IPR007278 Domain of unknown function DUF397 SMALA_RS24885 2623006ba861edc0fc73764621954cf0 73 Pfam PF04149 Domain of unknown function (DUF397) 11 66 8.0E-23 T 29-03-2018 IPR007278 Domain of unknown function DUF397 SMALA_RS25945 7356190670cab6fd86b9e626f8d343f3 503 Pfam PF11350 Protein of unknown function (DUF3152) 320 501 5.2E-57 T 29-03-2018 IPR022603 Domain of unknown function DUF3152 SMALA_RS25945 7356190670cab6fd86b9e626f8d343f3 503 SUPERFAMILY SSF55486 362 492 5.5E-13 T 29-03-2018 SMALA_RS25945 7356190670cab6fd86b9e626f8d343f3 503 Gene3D G3DSA:3.40.390.10 339 494 5.4E-8 T 29-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 SMALA_RS12390 52a9c8a988cefae969ed97c5df9c532f 216 SUPERFAMILY SSF52980 39 200 2.04E-10 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 SMALA_RS12390 52a9c8a988cefae969ed97c5df9c532f 216 Pfam PF05685 Putative restriction endonuclease 35 199 2.0E-13 T 29-03-2018 IPR008538 Domain of unknown function DUF820 SMALA_RS12390 52a9c8a988cefae969ed97c5df9c532f 216 Gene3D G3DSA:3.90.1570.10 22 206 2.0E-18 T 29-03-2018 SMALA_RS29905 844fca6f8f02d50a8bd5eb8ca9b01ed6 336 TIGRFAM TIGR04222 near_uncomplex: TIGR04222 domain 8 245 3.9E-36 T 29-03-2018 IPR026467 Ser/Gly rich, Cys interspersed, C-terminal domain SMALA_RS17000 063f364635802c0e278da221802c9d00 448 Pfam PF04024 PspC domain 36 89 1.3E-15 T 29-03-2018 IPR007168 Phage shock protein, PspC, N-terminal SMALA_RS40485 9ca5a0672aac164608a62fef926f9464 266 Pfam PF01925 Sulfite exporter TauE/SafE 3 259 2.4E-20 T 29-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 SMALA_RS01860 cc8e55d227b1580cd664ad2ccea9122a 403 Pfam PF16483 Beta-1,3-glucanase 42 399 4.3E-105 T 29-03-2018 IPR032477 Beta-1,3-glucanase, N-terminal KEGG: 00500+3.2.1.39 SMALA_RS11335 3cb3c75d96524b2eccf2e63c20cbf8fb 267 Pfam PF03883 Peroxide stress protein YaaA 2 247 5.8E-38 T 29-03-2018 IPR005583 Peroxide stress protein YaaA SMALA_RS20690 8b12226502c8878c5e6b5ea90136208c 178 Pfam PF10722 Putative bacterial sensory transduction regulator 30 155 1.3E-17 T 29-03-2018 IPR019660 Putative sensory transduction regulator YbjN SMALA_RS33585 7aa1a9590a7e35510de6934d92196812 213 Gene3D G3DSA:2.60.120.10 53 179 1.9E-7 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SMALA_RS33585 7aa1a9590a7e35510de6934d92196812 213 SUPERFAMILY SSF51182 32 176 3.85E-13 T 29-03-2018 IPR011051 RmlC-like cupin domain SMALA_RS08545 111c31555a10129ad25d6bbb2f83eec1 627 Gene3D G3DSA:3.50.50.60 7 625 9.4E-16 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMALA_RS08545 111c31555a10129ad25d6bbb2f83eec1 627 Pfam PF13454 FAD-NAD(P)-binding 16 197 9.1E-42 T 29-03-2018 SMALA_RS41490 67cebc6282e2c964189aeeef7a3fab9e 110 Gene3D G3DSA:1.10.10.10 24 74 0.0017 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS09315 12d3a9d7d4b7c2b24777aedea110722c 284 Pfam PF14100 Methane oxygenase PmoA 23 274 7.0E-59 T 29-03-2018 IPR029475 Methane oxygenase PmoA SMALA_RS02245 36485d548e2f95b9a8a3586244a80a1f 472 Gene3D G3DSA:3.40.50.850 4 265 8.6E-11 T 29-03-2018 SMALA_RS15875 6362e27fe3edcacad0dcdd89ea39923c 87 Pfam PF02467 Transcription factor WhiB 19 82 6.3E-27 T 29-03-2018 IPR034768 WhiB-like iron-sulfur binding domain SMALA_RS15875 6362e27fe3edcacad0dcdd89ea39923c 87 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 87 18.896 T 29-03-2018 IPR003482 Transcription factor WhiB SMALA_RS20935 47110171ffcd820a558d576fea807a06 84 Pfam PF11273 Protein of unknown function (DUF3073) 2 62 4.9E-22 T 29-03-2018 IPR021426 Protein of unknown function DUF3073 SMALA_RS16160 2c9b60a1f4ce412518baed346f205fff 76 Pfam PF14117 Domain of unknown function (DUF4287) 9 67 4.9E-23 T 29-03-2018 IPR025629 Protein of unknown function DUF4287 SMALA_RS07705 ef7460449bb5fbc20f8ed64f3f5ccf86 145 Gene3D G3DSA:3.30.565.10 12 144 1.5E-10 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS07705 ef7460449bb5fbc20f8ed64f3f5ccf86 145 Pfam PF13581 Histidine kinase-like ATPase domain 22 119 1.2E-9 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS07705 ef7460449bb5fbc20f8ed64f3f5ccf86 145 SUPERFAMILY SSF55874 36 126 4.01E-6 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS11265 e8859a6ddc19a1514702589d159fa97e 143 Pfam PF10025 Uncharacterized conserved protein (DUF2267) 17 137 9.0E-33 T 29-03-2018 IPR018727 Protein of unknown function DUF2267 SMALA_RS36265 c5b0ec558e6aeef5cd8e635043ba4400 233 Pfam PF07335 Fungal chitosanase of glycosyl hydrolase group 75 87 216 2.8E-25 T 29-03-2018 IPR009939 Fungal chitosanase KEGG: 00520+3.2.1.132 SMALA_RS14955 3410486db731b4bb6b18f5ecb00c7434 244 Gene3D G3DSA:3.40.50.300 2 243 0.0011 T 29-03-2018 SMALA_RS14955 3410486db731b4bb6b18f5ecb00c7434 244 Pfam PF08044 Domain of unknown function (DUF1707) 1 53 8.4E-25 T 29-03-2018 IPR012551 Protein of unknown function DUF1707 SMALA_RS42090 57918376156ca7c380650bf9216b4b2a 198 Gene3D G3DSA:2.30.110.10 8 197 2.7E-38 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS42090 57918376156ca7c380650bf9216b4b2a 198 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 9 149 4.9E-43 T 29-03-2018 IPR024747 Pyridoxamine 5'-phosphate oxidase-related SMALA_RS42090 57918376156ca7c380650bf9216b4b2a 198 SUPERFAMILY SSF50475 2 172 1.04E-45 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SMALA_RS10155 4f6a211c7f81e968dc8f8b4acc912ca3 154 Pfam PF13673 Acetyltransferase (GNAT) domain 50 152 2.3E-17 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SMALA_RS10155 4f6a211c7f81e968dc8f8b4acc912ca3 154 Gene3D G3DSA:3.40.630.30 3 154 4.8E-38 T 29-03-2018 SMALA_RS10155 4f6a211c7f81e968dc8f8b4acc912ca3 154 SUPERFAMILY SSF55729 4 153 1.2E-36 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SMALA_RS09980 083fed38016fbbbad9c5e8419ff7c050 231 TIGRFAM TIGR02234 trp_oprn_chp: membrane protein, TIGR02234 family 27 220 1.4E-42 T 29-03-2018 IPR011746 Trp biosynthesis associated, conserved hypothetical membrane protein SMALA_RS09980 083fed38016fbbbad9c5e8419ff7c050 231 Pfam PF09534 Tryptophan-associated transmembrane protein (Trp_oprn_chp) 35 219 1.2E-54 T 29-03-2018 IPR019051 Trp biosynthesis associated, transmembrane protein, Oprn/Chp SMALA_RS12885 70e810e0e9bb19b22913aa8db60c1b2f 88 Gene3D G3DSA:3.30.70.360 2 84 9.6E-4 T 29-03-2018 SMALA_RS09770 51190d4c605858c089c22a73e44e85b5 333 Pfam PF11271 Protein of unknown function (DUF3068) 5 305 3.1E-79 T 29-03-2018 IPR021424 Porin PorA SMALA_RS26045 797fab41dfc2b00aae366b160fe2c91a 489 Pfam PF03109 ABC1 family 113 227 3.0E-30 T 29-03-2018 IPR004147 UbiB domain SMALA_RS26045 797fab41dfc2b00aae366b160fe2c91a 489 Gene3D G3DSA:3.30.200.20 102 239 1.8E-22 T 29-03-2018 SMALA_RS26045 797fab41dfc2b00aae366b160fe2c91a 489 SUPERFAMILY SSF56112 195 313 5.22E-21 T 29-03-2018 IPR011009 Protein kinase-like domain SMALA_RS26045 797fab41dfc2b00aae366b160fe2c91a 489 SUPERFAMILY SSF56112 95 158 5.22E-21 T 29-03-2018 IPR011009 Protein kinase-like domain SMALA_RS20115 0e025cc0873e947788740c49bbb07c4e 164 Pfam PF07179 SseB protein N-terminal domain 79 152 1.0E-7 T 29-03-2018 IPR009839 SseB protein N-terminal domain SMALA_RS02515 7822e81303fd433495bcf6c8b8620a0b 113 Pfam PF09534 Tryptophan-associated transmembrane protein (Trp_oprn_chp) 10 108 1.8E-6 T 29-03-2018 IPR019051 Trp biosynthesis associated, transmembrane protein, Oprn/Chp SMALA_RS12410 20885deb659db677b80e3794be84e61f 241 TIGRFAM TIGR04222 near_uncomplex: TIGR04222 domain 13 129 1.1E-20 T 29-03-2018 IPR026467 Ser/Gly rich, Cys interspersed, C-terminal domain SMALA_RS27700 1f6d8db39bf13e0978b4adf24743cef0 332 Pfam PF00248 Aldo/keto reductase family 16 324 2.5E-60 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS27700 1f6d8db39bf13e0978b4adf24743cef0 332 SUPERFAMILY SSF51430 3 324 8.51E-85 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS27700 1f6d8db39bf13e0978b4adf24743cef0 332 Gene3D G3DSA:3.20.20.100 1 330 1.1E-91 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SMALA_RS07540 4d026e461752fb869e5692dd52938547 65 Gene3D G3DSA:1.10.10.10 1 65 1.6E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS39905 9c4ab8a79506fd1c5b8ef0b2df3a434b 272 Pfam PF02361 Cobalt transport protein 28 236 1.6E-25 T 29-03-2018 IPR003339 ABC/ECF transporter, transmembrane component SMALA_RS31910 8520c2b74edbd843e146c3e5f96ccddb 66 Pfam PF04149 Domain of unknown function (DUF397) 10 65 3.0E-24 T 29-03-2018 IPR007278 Domain of unknown function DUF397 SMALA_RS37615 fb26816913f5e5d4788d4a86ad88ccbc 202 Pfam PF08241 Methyltransferase domain 39 134 6.1E-21 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 SMALA_RS37615 fb26816913f5e5d4788d4a86ad88ccbc 202 SUPERFAMILY SSF53335 1 180 2.13E-33 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMALA_RS37615 fb26816913f5e5d4788d4a86ad88ccbc 202 Gene3D G3DSA:3.40.50.150 1 186 1.4E-29 T 29-03-2018 SMALA_RS12055 83407e7398af5457752da799699b72f1 307 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 72 292 1.1E-20 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain SMALA_RS12055 83407e7398af5457752da799699b72f1 307 Gene3D G3DSA:3.40.50.1110 63 306 2.2E-33 T 29-03-2018 SMALA_RS12055 83407e7398af5457752da799699b72f1 307 SUPERFAMILY SSF52266 65 205 5.34E-26 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain SMALA_RS12055 83407e7398af5457752da799699b72f1 307 SUPERFAMILY SSF52266 234 302 5.34E-26 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain SMALA_RS15095 d5ef7bb58bcc8764c7f65f33a58a8830 168 Pfam PF06271 RDD family 21 159 4.3E-20 T 29-03-2018 IPR010432 RDD SMALA_RS17325 dfb897d4468435b5faadf7fd973a1fac 92 Pfam PF10745 Protein of unknown function (DUF2530) 17 81 3.7E-9 T 29-03-2018 IPR019681 Protein of unknown function DUF2530 SMALA_RS07420 0d42a83b564d35d91bd2e19f2a02120f 196 Pfam PF11290 Protein of unknown function (DUF3090) 7 186 4.2E-68 T 29-03-2018 IPR021441 Protein of unknown function DUF3090 SMALA_RS07420 0d42a83b564d35d91bd2e19f2a02120f 196 TIGRFAM TIGR03847 TIGR03847: conserved hypothetical protein 5 190 1.6E-78 T 29-03-2018 IPR021441 Protein of unknown function DUF3090 SMALA_RS00340 5cbf172065c47150d5d9647ee9c5b2b8 95 Pfam PF05360 yiaA/B two helix domain 14 66 9.0E-19 T 29-03-2018 IPR008024 YiaAB two helix SMALA_RS18720 d2c3a81873cdaf26766c116288c12708 196 Gene3D G3DSA:2.60.60.30 19 189 4.1E-43 T 29-03-2018 SMALA_RS18720 d2c3a81873cdaf26766c116288c12708 196 Pfam PF02342 TerD domain 1 182 7.5E-43 T 29-03-2018 IPR003325 TerD domain GO:0006950 SMALA_RS24400 ef9c335bb2575c89882948dc29747f74 134 Pfam PF14155 Domain of unknown function (DUF4307) 22 130 2.2E-32 T 29-03-2018 IPR025443 Protein of unknown function DUF4307 SMALA_RS35715 6b0bd64f1d67a16df68913343bd64825 381 Gene3D G3DSA:1.50.10.10 24 380 1.6E-63 T 29-03-2018 SMALA_RS35715 6b0bd64f1d67a16df68913343bd64825 381 Pfam PF07470 Glycosyl Hydrolase Family 88 51 375 3.1E-74 T 29-03-2018 IPR010905 Glycosyl hydrolase, family 88 SMALA_RS35715 6b0bd64f1d67a16df68913343bd64825 381 SUPERFAMILY SSF48208 46 379 5.67E-59 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 SMALA_RS11475 a5a41d831095d61217122d4adb3c7ce4 491 Pfam PF02361 Cobalt transport protein 66 251 7.1E-8 T 29-03-2018 IPR003339 ABC/ECF transporter, transmembrane component SMALA_RS22185 cae25530ac5b97af469ee85a1be2d19e 407 Gene3D G3DSA:3.30.470.20 121 382 1.4E-28 T 29-03-2018 SMALA_RS22185 cae25530ac5b97af469ee85a1be2d19e 407 SUPERFAMILY SSF56059 130 334 1.77E-21 T 29-03-2018 SMALA_RS32655 cde378b59757a9c77b3adf6bd21f50d9 644 Pfam PF06152 Phage minor capsid protein 2 3 347 2.3E-64 T 29-03-2018 IPR009319 Bacteriophage A118, Gp4, minor capsid GO:0005198|GO:0019028 SMALA_RS33710 472530fda1a92f58f8590a53a43638fd 273 Gene3D G3DSA:3.90.550.10 5 265 1.2E-39 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS33710 472530fda1a92f58f8590a53a43638fd 273 SUPERFAMILY SSF53448 28 239 5.81E-44 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS33710 472530fda1a92f58f8590a53a43638fd 273 Pfam PF00535 Glycosyl transferase family 2 29 191 1.2E-27 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 SMALA_RS17655 30a2c59fa2bc1e4d1a9ef496dba5d862 573 Pfam PF07681 DoxX 232 333 7.9E-13 T 29-03-2018 IPR032808 DoxX family SMALA_RS24665 15859ab7d4b867d9fa4f60dfac4857b7 248 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 166 176 2.3E-6 T 29-03-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial SMALA_RS24665 15859ab7d4b867d9fa4f60dfac4857b7 248 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 109 126 2.3E-6 T 29-03-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial SMALA_RS24665 15859ab7d4b867d9fa4f60dfac4857b7 248 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 177 188 2.3E-6 T 29-03-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial SMALA_RS24665 15859ab7d4b867d9fa4f60dfac4857b7 248 Pfam PF01478 Type IV leader peptidase family 101 207 4.3E-13 T 29-03-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 SMALA_RS25015 ca145905e353f08a2a3c519a3d4c5df6 77 Gene3D G3DSA:1.10.1220.10 7 33 6.5E-8 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 SMALA_RS24145 32cac861d21e63e7ec42c467f7664c44 87 Pfam PF05120 Gas vesicle protein G 8 74 2.5E-23 T 29-03-2018 IPR007804 Gas vesicle protein GvpG SMALA_RS21960 6434cb94c7cff91f4cfd9b0a713397be 252 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 24 231 2.9E-48 T 29-03-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 SMALA_RS37440 324f672ce482e6d9360bdb1b076636e1 373 TIGRFAM TIGR00075 hypD: hydrogenase expression/formation protein HypD 5 361 2.4E-143 T 29-03-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 SMALA_RS37440 324f672ce482e6d9360bdb1b076636e1 373 PIRSF PIRSF005622 1 363 1.3E-152 T 29-03-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 SMALA_RS37440 324f672ce482e6d9360bdb1b076636e1 373 Pfam PF01924 Hydrogenase formation hypA family 13 359 4.2E-150 T 29-03-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 SMALA_RS07685 ae24c23537313450fca8c77952322e0e 280 Gene3D G3DSA:3.40.50.300 3 249 9.1E-11 T 29-03-2018 SMALA_RS07685 ae24c23537313450fca8c77952322e0e 280 SUPERFAMILY SSF52540 3 209 7.3E-12 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMALA_RS13085 0488f5f47d336ea5823740b27d90bc3b 407 Gene3D G3DSA:3.30.2010.10 78 166 1.1E-16 T 29-03-2018 SMALA_RS13085 0488f5f47d336ea5823740b27d90bc3b 407 Pfam PF01435 Peptidase family M48 86 279 1.1E-23 T 29-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 SMALA_RS09440 07f804859446cdab0e8f3b6ab33cb12e 194 Gene3D G3DSA:1.10.357.10 7 190 3.4E-33 T 29-03-2018 SMALA_RS09440 07f804859446cdab0e8f3b6ab33cb12e 194 SUPERFAMILY SSF46689 3 80 9.23E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SMALA_RS09440 07f804859446cdab0e8f3b6ab33cb12e 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 59 9.7E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMALA_RS09440 07f804859446cdab0e8f3b6ab33cb12e 194 SUPERFAMILY SSF48498 82 176 2.52E-6 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMALA_RS21430 a4c253218ad9ee5592e3a14b3a14ca28 247 PIRSF PIRSF006648 1 247 6.0E-63 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMALA_RS21430 a4c253218ad9ee5592e3a14b3a14ca28 247 Pfam PF01061 ABC-2 type transporter 6 211 1.1E-23 T 29-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 SMALA_RS22895 88441d864746b0ce36e11ffcdba66fd6 155 Gene3D G3DSA:3.30.565.10 22 150 7.5E-4 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS10620 83e3ded3be46eb5822adf8e504c928d2 198 Pfam PF11241 Protein of unknown function (DUF3043) 30 196 6.9E-63 T 29-03-2018 IPR021403 Protein of unknown function DUF3043 SMALA_RS37375 0c737b4acd3793a2881fc87f43fca9ad 179 SUPERFAMILY SSF110087 37 176 1.7E-22 T 29-03-2018 IPR007410 Copper chaperone PCuAC SMALA_RS37375 0c737b4acd3793a2881fc87f43fca9ad 179 Pfam PF04314 Copper chaperone PCu(A)C 65 169 7.8E-18 T 29-03-2018 IPR007410 Copper chaperone PCuAC SMALA_RS03115 def9fbbf836658b9d32ae287a2663efc 171 Gene3D G3DSA:1.20.120.450 1 171 2.5E-35 T 29-03-2018 SMALA_RS03115 def9fbbf836658b9d32ae287a2663efc 171 SUPERFAMILY SSF109854 2 166 1.19E-46 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes SMALA_RS03115 def9fbbf836658b9d32ae287a2663efc 171 Pfam PF04978 Protein of unknown function (DUF664) 22 167 2.4E-50 T 29-03-2018 IPR007061 Protein of unknown function DUF664 SMALA_RS32680 b1e674c953ec94f8f1d785a025fe143e 465 Pfam PF13701 Transposase DDE domain group 1 7 460 9.0E-43 T 29-03-2018 IPR025668 Transposase DDE domain SMALA_RS23495 c02cba00e5405b1c2a4f4d4caed8a29a 325 Gene3D G3DSA:1.25.40.10 31 205 3.6E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS23495 c02cba00e5405b1c2a4f4d4caed8a29a 325 Gene3D G3DSA:1.25.40.10 214 302 0.29 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS11485 f47a7d8a0d5d1c25952cf7a5e00a65cb 296 Pfam PF12822 ECF transporter, substrate-specific component 71 240 1.1E-20 T 29-03-2018 IPR024529 ECF transporter, substrate-specific component GO:0005215 SMALA_RS11485 f47a7d8a0d5d1c25952cf7a5e00a65cb 296 PIRSF PIRSF037395 1 264 1.1E-109 T 29-03-2018 IPR017196 ECF transporter, predicted substrate-specific component UCP037395 SMALA_RS26170 7aad30885f0837df2208e7323497011b 237 Pfam PF13398 Peptidase M50B-like 28 229 3.0E-59 T 29-03-2018 SMALA_RS40435 884ad044726778d407f376450bff29e7 570 Pfam PF02538 Hydantoinase B/oxoprolinase 3 519 2.9E-139 T 29-03-2018 IPR003692 Hydantoinase B/oxoprolinase GO:0003824 Reactome: R-HSA-174403 SMALA_RS15165 7a20d7681788117feab22e5cc07cec85 124 Gene3D G3DSA:1.10.3290.10 9 116 1.5E-6 T 29-03-2018 IPR003812 Fido domain SMALA_RS15165 7a20d7681788117feab22e5cc07cec85 124 Pfam PF02661 Fic/DOC family 11 80 8.1E-9 T 29-03-2018 IPR003812 Fido domain SMALA_RS08610 8ca1e11d0c3c194675bd384c16f8f37c 302 Pfam PF06386 Gas vesicle synthesis protein GvpL/GvpF 6 278 5.2E-61 T 29-03-2018 IPR009430 Gas vesicle protein GvpL/GvpF GO:0031411|GO:0031412 SMALA_RS03560 2cffa8eda5d6f7777728cd2a9960a610 322 Pfam PF06166 Protein of unknown function (DUF979) 5 322 9.8E-117 T 29-03-2018 IPR009323 Protein of unknown function DUF979 SMALA_RS26955 8d263e8b65adb4e4aeea80a13be7de64 251 Pfam PF01061 ABC-2 type transporter 12 215 2.2E-27 T 29-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 SMALA_RS26955 8d263e8b65adb4e4aeea80a13be7de64 251 PIRSF PIRSF006648 2 251 1.9E-46 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMALA_RS27415 1d61edb03637fbde77e76632ff3d9752 245 ProDom PD037589 AROM ARO OPERON REGULATED BY AROR BIOSYNTHESIS TRANSCRIPTION AMINO AROMATIC 18 240 2.0E-24 T 29-03-2018 IPR010843 Uncharacterised protein family AroM SMALA_RS27415 1d61edb03637fbde77e76632ff3d9752 245 Pfam PF07302 AroM protein 14 241 1.3E-73 T 29-03-2018 IPR010843 Uncharacterised protein family AroM SMALA_RS35525 ce437835f99a293c571b90e5c4155901 250 Pfam PF14016 Protein of unknown function (DUF4232) 118 244 4.4E-33 T 29-03-2018 IPR025326 Protein of unknown function DUF4232 SMALA_RS19855 658cff09a11afff1c6b34997e872dd78 470 Pfam PF01098 Cell cycle protein 83 449 4.5E-76 T 29-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 SMALA_RS29350 900307dc5e7a3bb00c7a06bb7828ed31 298 Pfam PF01040 UbiA prenyltransferase family 36 283 2.6E-52 T 29-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 SMALA_RS29350 900307dc5e7a3bb00c7a06bb7828ed31 298 Hamap MF_01635 4-hydroxybenzoate octaprenyltransferase [ubiA]. 12 297 24.026 T 29-03-2018 IPR031103 4-hydroxybenzoate octaprenyltransferase GO:0004659|GO:0006744|GO:0016021 Reactome: R-HSA-1268020|Reactome: R-HSA-2142789 SMALA_RS19890 e3aa83fbf0e8dada57e5e5542df8922e 488 Pfam PF10009 Uncharacterized protein conserved in bacteria (DUF2252) 77 474 5.0E-136 T 29-03-2018 IPR018721 Protein of unknown function DUF2252 SMALA_RS17320 6b817fbd3f726baf6f06b0eb42553fbc 489 Pfam PF00860 Permease family 41 441 7.1E-31 T 29-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 SMALA_RS21610 e3aa045408a5216e065976f1f219c38e 207 Pfam PF01551 Peptidase family M23 94 195 2.2E-32 T 29-03-2018 IPR016047 Peptidase M23 SMALA_RS21610 e3aa045408a5216e065976f1f219c38e 207 SUPERFAMILY SSF51261 58 200 1.46E-43 T 29-03-2018 IPR011055 Duplicated hybrid motif SMALA_RS21610 e3aa045408a5216e065976f1f219c38e 207 Gene3D G3DSA:2.70.70.10 32 203 4.3E-45 T 29-03-2018 SMALA_RS35550 32fd3b2856c43c5ad2fec9398163cf6e 498 Gene3D G3DSA:3.40.50.261 360 482 5.1E-5 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMALA_RS23260 f2ae7ec1faf053a93ea8d30a3ded7ea1 69 Pfam PF04149 Domain of unknown function (DUF397) 10 61 2.6E-21 T 29-03-2018 IPR007278 Domain of unknown function DUF397 SMALA_RS24635 3a63bf25d45b1433698b79c833055706 241 Pfam PF13400 Putative Flp pilus-assembly TadE/G-like 12 59 7.8E-5 T 29-03-2018 IPR028087 Putative Flp pilus-assembly TadG-like, N-terminal SMALA_RS07885 fd5fd13e2ef7fdcde8a74b65cda2eef1 197 SUPERFAMILY SSF55874 68 167 8.15E-7 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS07885 fd5fd13e2ef7fdcde8a74b65cda2eef1 197 Pfam PF13581 Histidine kinase-like ATPase domain 43 168 2.4E-10 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS07885 fd5fd13e2ef7fdcde8a74b65cda2eef1 197 Gene3D G3DSA:3.30.565.10 34 181 7.0E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMALA_RS11675 2735366f7918949054cc7f1012fac0cb 161 Pfam PF07681 DoxX 21 97 3.0E-8 T 29-03-2018 IPR032808 DoxX family SMALA_RS22150 c518f5d2995d70e2f2b9f8a3833dfd0f 304 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 30 175 1.4E-31 T 29-03-2018 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS40935 abdc76ab5e2edff1cdf8384dcdf8f689 175 Pfam PF13160 Protein of unknown function (DUF3995) 26 153 1.8E-16 T 29-03-2018 IPR025058 Protein of unknown function DUF3995 SMALA_RS15100 8178e94916274d539d10b49eeb21df51 191 Pfam PF06271 RDD family 50 183 5.4E-26 T 29-03-2018 IPR010432 RDD SMALA_RS15530 703bae9ff675e01dbc45dc2b2f701387 225 Pfam PF04886 PT repeat 104 138 6.9E-7 T 29-03-2018 IPR006970 PT repeat SMALA_RS25600 c05644e7883df95a1c5577a69477e7ed 268 Gene3D G3DSA:1.10.3100.10 1 133 6.0E-5 T 29-03-2018 IPR027910 YdiL-like domain SMALA_RS24605 5ded22851240b76e09f94481208131b7 234 TIGRFAM TIGR03177 pilus_cpaB: Flp pilus assembly protein CpaB 10 215 7.7E-25 T 29-03-2018 IPR017592 Pilus assembly, Flp-type CpaB SMALA_RS24605 5ded22851240b76e09f94481208131b7 234 Pfam PF16976 Flp pilus assembly protein RcpC/CpaB 107 212 5.0E-18 T 29-03-2018 IPR031571 Flp pilus assembly protein RcpC/CpaB domain SMALA_RS24605 5ded22851240b76e09f94481208131b7 234 Gene3D G3DSA:3.90.1210.10 40 106 2.5E-9 T 29-03-2018 SMALA_RS28810 636f1d0d2f488a55e7845bf89c0541ef 401 Pfam PF01594 AI-2E family transporter 45 366 1.9E-73 T 29-03-2018 IPR002549 Transmembrane protein TqsA-like SMALA_RS09495 16b557a7a21c227b03894aea842d8a93 257 Pfam PF01061 ABC-2 type transporter 29 224 2.0E-21 T 29-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 SMALA_RS09495 16b557a7a21c227b03894aea842d8a93 257 PIRSF PIRSF006648 3 257 2.5E-30 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMALA_RS17730 f5f8c11fa1e3a6a0e3d2ed70dbcb56b4 252 SUPERFAMILY SSF53448 4 218 2.81E-22 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS17730 f5f8c11fa1e3a6a0e3d2ed70dbcb56b4 252 Gene3D G3DSA:3.90.550.10 2 250 5.6E-19 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SMALA_RS17730 f5f8c11fa1e3a6a0e3d2ed70dbcb56b4 252 Pfam PF00535 Glycosyl transferase family 2 10 112 1.2E-5 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 SMALA_RS43325 d1d12e8cd192aef163234cea07fe2ffb 69 Gene3D G3DSA:1.10.1220.10 1 43 3.0E-4 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 SMALA_RS24135 3cbe7a4e979d954dd4ff015dfedfb20f 273 Pfam PF06386 Gas vesicle synthesis protein GvpL/GvpF 11 267 3.9E-54 T 29-03-2018 IPR009430 Gas vesicle protein GvpL/GvpF GO:0031411|GO:0031412 SMALA_RS13070 52f3352f34965e764a8d94b3e8030486 616 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 525 612 7.3E-11 T 29-03-2018 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain SMALA_RS13070 52f3352f34965e764a8d94b3e8030486 616 Gene3D G3DSA:3.40.220.10 65 556 4.1E-4 T 29-03-2018 SMALA_RS14380 988a547b36f8a45c4974a246d23ff877 503 Gene3D G3DSA:3.40.50.880 200 488 1.9E-9 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS30015 9aeccf4548c1dc7806d820187d9b9dea 158 SUPERFAMILY SSF52402 18 145 8.37E-20 T 29-03-2018 SMALA_RS30015 9aeccf4548c1dc7806d820187d9b9dea 158 Gene3D G3DSA:3.40.50.620 11 148 7.2E-9 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMALA_RS09295 87bcf376f811ef0c27716935743a2b90 481 Pfam PF00860 Permease family 37 434 7.7E-30 T 29-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 SMALA_RS18550 427e357d5b5b6c7fa759d739e42f90c4 272 Pfam PF00482 Type II secretion system (T2SS), protein F 134 256 2.8E-13 T 29-03-2018 IPR018076 Type II secretion system F domain SMALA_RS33790 03024d5a3c10ff622cf07fb97cea0a1c 120 Pfam PF13788 Domain of unknown function (DUF4180) 9 118 1.3E-39 T 29-03-2018 IPR025438 Domain of unknown function DUF4180 SMALA_RS26285 bb4e6dfb2f73980bf290d1580275e6fe 544 Pfam PF00474 Sodium:solute symporter family 44 410 1.0E-20 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 SMALA_RS39810 dc7f56a7f3b29e9d7e9f0c6f05115401 335 Gene3D G3DSA:1.10.3470.10 12 328 2.4E-31 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SMALA_RS39810 dc7f56a7f3b29e9d7e9f0c6f05115401 335 Pfam PF02653 Branched-chain amino acid transport system / permease component 56 322 3.3E-43 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 SMALA_RS07795 054f78f9dc3369f28cafb81aab42840c 169 Gene3D G3DSA:1.25.40.10 14 158 6.0E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS05290 f441aa637c12aa56d78dbc47a3e24885 325 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 306 2.7E-14 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS05290 f441aa637c12aa56d78dbc47a3e24885 325 SUPERFAMILY SSF161098 79 308 1.09E-49 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS05290 f441aa637c12aa56d78dbc47a3e24885 325 Gene3D G3DSA:1.10.3720.10 35 321 2.8E-39 T 29-03-2018 SMALA_RS39110 37b580d85465104fb2d6d252deb715b1 272 Pfam PF10014 2OG-Fe dioxygenase 21 232 2.3E-47 T 29-03-2018 IPR018724 2OG-Fe dioxygenase SMALA_RS09500 250c3a1c1b9d8dbfa8f54a2c4fa9c166 330 Pfam PF02628 Cytochrome oxidase assembly protein 75 294 4.9E-12 T 29-03-2018 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 SMALA_RS09500 250c3a1c1b9d8dbfa8f54a2c4fa9c166 330 Pfam PF02628 Cytochrome oxidase assembly protein 26 69 1.3E-9 T 29-03-2018 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 SMALA_RS43160 43741e4200462352f195840dfd26c5c3 114 Gene3D G3DSA:3.30.450.20 3 81 5.1E-4 T 29-03-2018 SMALA_RS05135 7908bc1bb7b6be15b595e52140cc9fef 278 Pfam PF02517 CAAX protease self-immunity 108 196 7.1E-15 T 29-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 SMALA_RS23245 01f832b3f74a22863913666b4262be3a 523 Pfam PF00474 Sodium:solute symporter family 33 416 8.7E-28 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 SMALA_RS17230 82e619ce4e4de2bb0c74149d12204bac 571 Pfam PF07287 Acyclic terpene utilisation family protein AtuA 9 337 2.8E-124 T 29-03-2018 IPR010839 Acyclic terpene utilisation SMALA_RS20860 6fe4003d72cc9d10faae139a9eefa4d4 499 Gene3D G3DSA:3.40.50.880 194 493 4.2E-12 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SMALA_RS31890 d414293e9e51e760a1c51132498aa1d9 137 Pfam PF04686 Streptomyces sporulation and cell division protein, SsgA 23 120 2.2E-34 T 29-03-2018 IPR006776 Sporulation-specific cell division protein SsgB GO:0051301 SMALA_RS20440 047be4dd62bddad22f29eecdc2e4108c 253 Pfam PF01925 Sulfite exporter TauE/SafE 10 251 2.1E-30 T 29-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 SMALA_RS11940 c038bd523c5959ee1df5f0dfa0a7bc35 146 Pfam PF11253 Protein of unknown function (DUF3052) 15 139 2.7E-57 T 29-03-2018 IPR021412 Protein of unknown function DUF3052 SMALA_RS43275 4f1f31fe481b5fb110dc63d36b04c2bc 135 Pfam PF03668 P-loop ATPase protein family 5 123 2.8E-14 T 29-03-2018 IPR005337 RapZ-like family GO:0005524 SMALA_RS20545 016c41bf8f82588018ca035a564a5b03 231 Pfam PF14016 Protein of unknown function (DUF4232) 95 183 1.9E-12 T 29-03-2018 IPR025326 Protein of unknown function DUF4232 SMALA_RS17560 49a894f5e3fa91ce0b4beb37dde2165e 327 Gene3D G3DSA:2.60.120.260 185 323 6.2E-25 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS17560 49a894f5e3fa91ce0b4beb37dde2165e 327 SUPERFAMILY SSF49785 194 323 7.65E-11 T 29-03-2018 IPR008979 Galactose-binding domain-like SMALA_RS23375 81484b9872500049191374ee72cc697e 295 Gene3D G3DSA:3.20.20.70 2 295 1.8E-109 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SMALA_RS23375 81484b9872500049191374ee72cc697e 295 Pfam PF05853 beta-keto acid cleavage enzyme 5 291 8.2E-103 T 29-03-2018 IPR008567 3-keto-5-aminohexanoate cleavage enzyme GO:0016740|GO:0019475 KEGG: 00310+2.3.1.247|KEGG: 00600+2.3.1.24 SMALA_RS37030 752b95a08bed6d133ea226a966d7b5e5 267 Gene3D G3DSA:3.10.350.10 194 250 1.1E-6 T 29-03-2018 SMALA_RS22310 e7ddbfeefa3daa24c08a77886d928275 527 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 16 519 14.828 T 29-03-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 SMALA_RS22310 e7ddbfeefa3daa24c08a77886d928275 527 Pfam PF00361 Proton-conducting membrane transporter 141 446 5.8E-50 T 29-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS11825 6578ddb9921c253cc7d19a51f2481050 455 Gene3D G3DSA:1.25.40.10 26 436 3.5E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMALA_RS24430 63f21e6046700ee9b41fd3566daf94c4 236 Pfam PF03006 Haemolysin-III related 28 225 2.1E-42 T 29-03-2018 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 SMALA_RS03665 09afab6357d308173aea6f548b41d34f 81 Pfam PF04149 Domain of unknown function (DUF397) 25 74 1.6E-10 T 29-03-2018 IPR007278 Domain of unknown function DUF397 SMALA_RS31790 a6f9d62672252d26b1b87c1692611793 103 Pfam PF05121 Gas vesicle protein K 11 95 2.5E-35 T 29-03-2018 IPR007805 Gas vesicle protein GvpK GO:0031412 SMALA_RS05750 cbca10d202a572a3a4a5be9dc1b9d118 385 Gene3D G3DSA:1.20.1050.50 12 183 7.5E-42 T 29-03-2018 SMALA_RS02870 057d85c063ca12480b9ea9b460ceca70 275 Gene3D G3DSA:3.30.540.10 15 157 2.4E-21 T 29-03-2018 SMALA_RS02870 057d85c063ca12480b9ea9b460ceca70 275 Gene3D G3DSA:3.40.190.80 158 275 5.0E-23 T 29-03-2018 SMALA_RS02870 057d85c063ca12480b9ea9b460ceca70 275 SUPERFAMILY SSF56655 18 271 3.66E-45 T 29-03-2018 SMALA_RS02870 057d85c063ca12480b9ea9b460ceca70 275 Pfam PF00459 Inositol monophosphatase family 23 266 1.1E-29 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 SMALA_RS02870 057d85c063ca12480b9ea9b460ceca70 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 191 212 3.4E-19 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 SMALA_RS02870 057d85c063ca12480b9ea9b460ceca70 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 222 246 3.4E-19 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 SMALA_RS02870 057d85c063ca12480b9ea9b460ceca70 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 142 165 3.4E-19 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 SMALA_RS02870 057d85c063ca12480b9ea9b460ceca70 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 93 109 3.4E-19 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 SMALA_RS36030 7def0e537410fde70f9b90f7fe1d729e 476 Pfam PF03559 NDP-hexose 2,3-dehydratase 269 471 8.1E-78 T 29-03-2018 IPR005212 NDP-hexose 2,3-dehydratase SMALA_RS36030 7def0e537410fde70f9b90f7fe1d729e 476 Pfam PF03559 NDP-hexose 2,3-dehydratase 26 230 2.6E-85 T 29-03-2018 IPR005212 NDP-hexose 2,3-dehydratase SMALA_RS31220 81dc92154f19bb5060adbed789240db3 258 Pfam PF10099 Anti-sigma-K factor rskA 58 252 3.0E-35 T 29-03-2018 IPR018764 Anti-sigma K factor RskA GO:0005886|GO:0016021 SMALA_RS03360 60b530c082b2be4083fb9b559d7d5c12 306 Pfam PF05949 Bacterial protein of unknown function (DUF881) 137 279 1.3E-38 T 29-03-2018 IPR010273 Protein of unknown function DUF881 SMALA_RS31385 461e95b56820417376f3d9a8831d7e8e 570 Pfam PF01040 UbiA prenyltransferase family 35 192 1.8E-19 T 29-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 SMALA_RS30215 c4e7b2c63ba4cffdac49ea87f29f8865 67 Pfam PF04149 Domain of unknown function (DUF397) 6 58 1.2E-13 T 29-03-2018 IPR007278 Domain of unknown function DUF397 SMALA_RS16565 2cad27c9624335a0759553decb070540 408 Pfam PF01757 Acyltransferase family 62 389 2.2E-21 T 29-03-2018 IPR002656 Acyltransferase 3 GO:0016747 SMALA_RS31975 11a4b7a149b027d667483e8fc3a7ad7b 290 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 23 259 1.6E-57 T 29-03-2018 IPR018713 Domain of unknown function DUF2236 SMALA_RS11095 875a8a46d38951eaaa3a444a7f2796e5 527 Gene3D G3DSA:4.10.320.10 167 202 0.062 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 SMALA_RS11095 875a8a46d38951eaaa3a444a7f2796e5 527 Pfam PF04213 Htaa 61 217 1.1E-49 T 29-03-2018 IPR007331 Htaa SMALA_RS11095 875a8a46d38951eaaa3a444a7f2796e5 527 Pfam PF04213 Htaa 274 433 8.7E-54 T 29-03-2018 IPR007331 Htaa SMALA_RS21395 59102c111e86ff25587965d4baaa0fd9 118 Pfam PF03795 YCII-related domain 4 98 6.2E-13 T 29-03-2018 IPR005545 YCII-related SMALA_RS21395 59102c111e86ff25587965d4baaa0fd9 118 Gene3D G3DSA:3.30.70.1060 1 118 1.5E-33 T 29-03-2018 SMALA_RS21395 59102c111e86ff25587965d4baaa0fd9 118 SUPERFAMILY SSF54909 3 116 5.9E-27 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel SMALA_RS21495 206c9efc60c227a20e24278c08dbcb27 228 Pfam PF11209 Protein of unknown function (DUF2993) 20 219 4.4E-32 T 29-03-2018 IPR021373 Protein of unknown function DUF2993 SMALA_RS16345 a59c9e49f242a486130c28de06222504 68 Pfam PF13822 Acyl-CoA carboxylase epsilon subunit 2 61 5.8E-20 T 29-03-2018 IPR032716 Acyl-CoA carboxylase epsilon subunit SMALA_RS33850 9bcd94335ff20346f3e82b38b0213fc3 323 Gene3D G3DSA:1.10.3470.10 39 306 2.1E-30 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SMALA_RS33850 9bcd94335ff20346f3e82b38b0213fc3 323 Pfam PF02653 Branched-chain amino acid transport system / permease component 36 300 4.0E-48 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 SMALA_RS38465 3c32ff562ff02c507e078df6eb8eb68f 551 Gene3D G3DSA:3.30.460.10 3 150 1.8E-6 T 29-03-2018 SMALA_RS38465 3c32ff562ff02c507e078df6eb8eb68f 551 SUPERFAMILY SSF81301 14 63 6.91E-6 T 29-03-2018 SMALA_RS07630 a47998af804ecdaf14f1a75afc58fc1e 239 Pfam PF03771 Domain of unknown function (DUF317) 53 115 3.2E-8 T 29-03-2018 IPR005523 Domain of unknown function DUF317 SMALA_RS07630 a47998af804ecdaf14f1a75afc58fc1e 239 Pfam PF03771 Domain of unknown function (DUF317) 171 220 1.9E-7 T 29-03-2018 IPR005523 Domain of unknown function DUF317 SMALA_RS07630 a47998af804ecdaf14f1a75afc58fc1e 239 Gene3D G3DSA:3.10.105.10 84 190 0.0012 T 29-03-2018 SMALA_RS11655 c7330d53271be1d4dcc6135ea7be04e7 193 Pfam PF01169 Uncharacterized protein family UPF0016 110 183 1.0E-18 T 29-03-2018 IPR001727 Gdt1 family SMALA_RS11655 c7330d53271be1d4dcc6135ea7be04e7 193 Pfam PF01169 Uncharacterized protein family UPF0016 10 79 6.7E-15 T 29-03-2018 IPR001727 Gdt1 family SMALA_RS25605 826769ed7f935932919f69fdd9f1f0c8 66 Pfam PF04149 Domain of unknown function (DUF397) 5 57 3.1E-12 T 29-03-2018 IPR007278 Domain of unknown function DUF397 SMALA_RS07405 44ce621d9dd34594b6a706937cb4648a 382 Gene3D G3DSA:1.10.287.100 219 258 3.0E-6 T 29-03-2018 SMALA_RS07405 44ce621d9dd34594b6a706937cb4648a 382 Pfam PF09754 PAC2 family 19 237 6.5E-52 T 29-03-2018 IPR019151 Proteasome assembly chaperone 2 SMALA_RS07405 44ce621d9dd34594b6a706937cb4648a 382 SUPERFAMILY SSF159659 3 261 4.97E-88 T 29-03-2018 SMALA_RS32745 bb45d2d36ea7ea6d0d126b9046644b90 93 Pfam PF13453 Transcription factor zinc-finger 2 40 1.2E-17 T 29-03-2018 IPR027392 Transcription factor zinc-finger SMALA_RS07655 a48bac6772d7af32798be836af8144a0 144 Pfam PF07811 TadE-like protein 15 57 6.1E-10 T 29-03-2018 IPR012495 TadE-like SMALA_RS13700 779cf2a02989de0de2c5d405f2189722 325 TIGRFAM TIGR03891 thiopep_ocin: thiopeptide-type bacteriocin biosynthesis domain 60 321 5.9E-50 T 29-03-2018 IPR023809 Thiopeptide-type bacteriocin biosynthesis domain SMALA_RS13700 779cf2a02989de0de2c5d405f2189722 325 Pfam PF14028 Lantibiotic biosynthesis dehydratase C-term 73 321 1.4E-29 T 29-03-2018 IPR023809 Thiopeptide-type bacteriocin biosynthesis domain SMALA_RS29245 cac6f1664e43d77a28e23b45b82e05d2 273 PIRSF PIRSF010219 5 231 6.8E-77 T 29-03-2018 IPR016566 Uncharacterised conserved protein UCP010219 SMALA_RS29245 cac6f1664e43d77a28e23b45b82e05d2 273 Pfam PF11361 Protein of unknown function (DUF3159) 31 217 9.9E-58 T 29-03-2018 IPR016566 Uncharacterised conserved protein UCP010219 SMALA_RS24090 bc64e5ec6556378d77b437987b810c2c 1030 Pfam PF14435 SUKH-4 immunity protein 849 1024 4.5E-43 T 29-03-2018 IPR025851 SUKH-4 immunity protein SMALA_RS24090 bc64e5ec6556378d77b437987b810c2c 1030 Pfam PF14440 Xanthomonas XOO_2897-like deaminase 710 809 1.3E-33 T 29-03-2018 IPR032722 Deaminase, Xanthomonas XOO_2897-like SMALA_RS22885 b1895e8e4c761b523026de7f0bb6025b 70 Pfam PF04149 Domain of unknown function (DUF397) 4 57 1.6E-14 T 29-03-2018 IPR007278 Domain of unknown function DUF397 SMALA_RS08430 32ac3ff8c8d6cb9efcbb8070df77f918 258 Pfam PF01925 Sulfite exporter TauE/SafE 13 255 2.0E-22 T 29-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 SMALA_RS19810 f6996b946095666aec629516f5a914ea 85 Pfam PF06781 Cell division protein CrgA 2 85 1.7E-28 T 29-03-2018 IPR009619 Cell division protein CrgA SMALA_RS19810 f6996b946095666aec629516f5a914ea 85 Hamap MF_00631 Cell division protein CrgA [crgA]. 1 85 22.766 T 29-03-2018 IPR009619 Cell division protein CrgA SMALA_RS40300 5b33c86063bbb0f768158dcf9b2bb393 677 Pfam PF00361 Proton-conducting membrane transporter 132 423 5.3E-49 T 29-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS40300 5b33c86063bbb0f768158dcf9b2bb393 677 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 169 193 8.8E-10 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS40300 5b33c86063bbb0f768158dcf9b2bb393 677 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 391 417 8.8E-10 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS40300 5b33c86063bbb0f768158dcf9b2bb393 677 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 240 264 8.8E-10 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMALA_RS29005 7261e62ae81fe9a58acba68fb619ace9 217 Gene3D G3DSA:3.40.50.720 51 209 9.3E-4 T 29-03-2018 SMALA_RS11415 3a8cd6985b39a9949bde5c68a4cc545c 366 SUPERFAMILY SSF48208 41 343 1.59E-40 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 SMALA_RS11415 3a8cd6985b39a9949bde5c68a4cc545c 366 Gene3D G3DSA:1.50.10.20 22 351 1.1E-29 T 29-03-2018 SMALA_RS02140 6d94087f7ad0e20217e4f19cb5156967 154 Pfam PF10027 Predicted integral membrane protein (DUF2269) 4 148 1.9E-6 T 29-03-2018 IPR018729 Protein of unknown function DUF2269, transmembrane SMALA_RS01435 3c1d4cfa518ead33e9d09b2c7857c38b 232 Gene3D G3DSA:2.60.120.560 42 226 9.1E-18 T 29-03-2018 SMALA_RS01435 3c1d4cfa518ead33e9d09b2c7857c38b 232 Pfam PF06439 Domain of Unknown Function (DUF1080) 155 224 2.4E-7 T 29-03-2018 IPR010496 Domain of unknown function DUF1080 SMALA_RS26280 3f3d028578bf05192c9efc1503e70aa4 121 Pfam PF06993 Protein of unknown function (DUF1304) 11 117 3.4E-40 T 29-03-2018 IPR009732 Protein of unknown function DUF1304 SMALA_RS00720 21f9a7fe28fccaaf18e180ecb76495a3 380 Pfam PF01384 Phosphate transporter family 22 320 2.7E-79 T 29-03-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 SMALA_RS37365 97db8879976cd7e259da7eb6c82cd28d 74 Pfam PF13490 Putative zinc-finger 3 39 2.6E-9 T 29-03-2018 IPR027383 Putative zinc-finger SMALA_RS09395 b1371e149a4b7b4325465004600e564b 312 Pfam PF00892 EamA-like transporter family 7 137 2.3E-12 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SMALA_RS09395 b1371e149a4b7b4325465004600e564b 312 Pfam PF00892 EamA-like transporter family 166 282 1.7E-9 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SMALA_RS09395 b1371e149a4b7b4325465004600e564b 312 SUPERFAMILY SSF103481 38 140 6.41E-12 T 29-03-2018 SMALA_RS09395 b1371e149a4b7b4325465004600e564b 312 SUPERFAMILY SSF103481 187 289 9.29E-13 T 29-03-2018 SMALA_RS21030 881843939f8afedc0d0b294bce9ee594 273 Pfam PF07920 Protein of unknown function (DUF1684) 126 264 1.7E-43 T 29-03-2018 IPR012467 Protein of unknown function DUF1684 SMALA_RS38510 3dc12e66b2a5e90d3988a52145eadbe9 152 SUPERFAMILY SSF46785 2 146 5.94E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS38510 3dc12e66b2a5e90d3988a52145eadbe9 152 Gene3D G3DSA:1.10.10.10 11 150 3.5E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SMALA_RS03955 947bce18deb3a3427c67d1e4c723b722 302 Pfam PF10977 Protein of unknown function (DUF2797) 45 273 2.2E-22 T 29-03-2018 IPR021246 Protein of unknown function DUF2797 SMALA_RS18215 b08a73765a6ac6e526242d92c5c67723 93 Pfam PF04149 Domain of unknown function (DUF397) 26 78 4.4E-16 T 29-03-2018 IPR007278 Domain of unknown function DUF397 SMALA_RS27820 e24640f0d6a4f83b3e8c0262eaaa84e3 79 Pfam PF13822 Acyl-CoA carboxylase epsilon subunit 18 77 1.4E-15 T 29-03-2018 IPR032716 Acyl-CoA carboxylase epsilon subunit SMALA_RS09675 46738565027331a241c782173b5fecea 217 Pfam PF14273 Domain of unknown function (DUF4360) 34 212 3.5E-68 T 29-03-2018 IPR025649 Protein of unknown function DUF4360 SMALA_RS33580 e3741a75fe5fa2f247e50b371a2a3a65 398 SUPERFAMILY SSF53795 157 234 1.19E-7 T 29-03-2018 SMALA_RS33580 e3741a75fe5fa2f247e50b371a2a3a65 398 Gene3D G3DSA:3.40.50.300 156 358 4.8E-10 T 29-03-2018 SMALA_RS01145 0a451181bb568e85a2eb649cf645c01d 332 Pfam PF01040 UbiA prenyltransferase family 22 244 1.3E-35 T 29-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 SMALA_RS41225 957724c3fcec12423ed278d9d2f77120 127 Gene3D G3DSA:3.30.160.100 5 116 3.1E-4 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 SMALA_RS14575 4e8d5fbd2841712650fd05f699a965f1 415 Pfam PF09375 Imelysin 176 392 9.8E-19 T 29-03-2018 IPR018976 Peptidase M75, Imelysin SMALA_RS29685 e2d476fe95fb012606f720031b50c462 284 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 96 276 4.0E-17 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS29685 e2d476fe95fb012606f720031b50c462 284 SUPERFAMILY SSF161098 11 284 4.02E-67 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS29685 e2d476fe95fb012606f720031b50c462 284 Gene3D G3DSA:1.10.3720.10 6 272 3.6E-36 T 29-03-2018 SMALA_RS19475 869cf3e78fcfd7b6367e5bc6138640be 126 Pfam PF04020 Mycobacterial 4 TMS phage holin, superfamily IV 3 115 3.3E-29 T 29-03-2018 IPR007165 Mycobacterial 4 TMS phage holin, superfamily IV SMALA_RS13315 76c5d446df79da10e368fdbff9d4c9a6 504 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 20 440 6.3E-146 T 29-03-2018 IPR002823 Protein of unknown function DUF112, transmembrane SMALA_RS37670 24122020b2803446518cb0081cc8517e 234 Gene3D G3DSA:3.40.190.10 1 190 6.2E-5 T 29-03-2018 SMALA_RS41520 00268cafc25e150ce656731b99ca3116 486 Pfam PF00474 Sodium:solute symporter family 31 411 1.2E-38 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 SMALA_RS06915 4558807f382fda8e29b8e807333b6b88 604 Pfam PF13520 Amino acid permease 51 420 1.3E-22 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMALA_RS24625 e59de15794ebe60388e371243ff4569a 312 Pfam PF00482 Type II secretion system (T2SS), protein F 145 268 1.5E-18 T 29-03-2018 IPR018076 Type II secretion system F domain SMALA_RS31810 fcb5c776043f5cdd41e091b658507291 324 Gene3D G3DSA:1.10.3720.10 3 299 6.5E-44 T 29-03-2018 SMALA_RS31810 fcb5c776043f5cdd41e091b658507291 324 SUPERFAMILY SSF161098 93 293 1.16E-22 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS31810 fcb5c776043f5cdd41e091b658507291 324 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 309 2.4E-37 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMALA_RS16255 e0512de0249f3a3897d001e907c0deb3 382 Pfam PF11991 Tryptophan dimethylallyltransferase 36 317 6.7E-10 T 29-03-2018 IPR017795 Aromatic prenyltransferase, DMATS-type GO:0009820|GO:0016765 SMALA_RS39950 09d02f8d0b1d5de386dacd7abd169390 247 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 49 119 5.2E-22 T 29-03-2018 IPR025161 Putative transposase IS4/IS5 family SMALA_RS27960 affe19290edcc8c14a9174272ef8cd19 147 Pfam PF12028 Protein of unknown function (DUF3515) 15 144 1.6E-28 T 29-03-2018 IPR021903 Protein of unknown function DUF3515 SMALA_RS01830 6f8659203f87b04667eda39966155ab5 425 Gene3D G3DSA:1.20.91.10 250 333 2.9E-15 T 29-03-2018 SMALA_RS01830 6f8659203f87b04667eda39966155ab5 425 Pfam PF00999 Sodium/hydrogen exchanger family 15 399 1.4E-48 T 29-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 SMALA_RS32070 4499dbae2919f1dfbc9255b4045f494d 311 Pfam PF01061 ABC-2 type transporter 64 269 1.1E-14 T 29-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 SMALA_RS01770 41d71edcea5bc640b7ed25683aef7e46 337 Pfam PF03773 Predicted permease 57 332 6.5E-44 T 29-03-2018 IPR005524 Predicted permease DUF318 SMALA_RS19360 7208a4d708486aaaecc54fe81807380b 242 Pfam PF12679 ABC-2 family transporter protein 46 173 3.7E-11 T 29-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 SMALA_RS09050 5a1545c62833af76afb7c2cc377c71dd 230 Pfam PF07947 YhhN family 37 212 5.1E-30 T 29-03-2018 IPR012506 YhhN-like GO:0016021 SMALA_RS21555 f47bd5f0fecbe2a0ba74dc9f84f9e865 433 Pfam PF11209 Protein of unknown function (DUF2993) 117 266 3.3E-25 T 29-03-2018 IPR021373 Protein of unknown function DUF2993 SMALA_RS29550 38e59176ef86633c3e2453d6afe6e818 152 Pfam PF13160 Protein of unknown function (DUF3995) 1 88 2.9E-10 T 29-03-2018 IPR025058 Protein of unknown function DUF3995 SMALA_RS04545 e5ddd7129245409e795c73394dcefe67 408 Pfam PF04235 Protein of unknown function (DUF418) 235 406 2.3E-30 T 29-03-2018 IPR007349 Domain of unknown function DUF418 SMALA_RS03725 403f5da34050b6927b1e7d1f24ceccd0 317 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 25 256 2.4E-52 T 29-03-2018 IPR018713 Domain of unknown function DUF2236 SMALA_RS19140 9d044b3029f01d7d5b359f7ab2d6daae 159 Gene3D G3DSA:3.40.190.10 7 150 0.0011 T 29-03-2018 SMALA_RS25845 f768e8bfc8bf552a2c292e4b989b9079 176 Pfam PF06210 Protein of unknown function (DUF1003) 39 140 1.4E-38 T 29-03-2018 IPR010406 Protein of unknown function DUF1003 SMALA_RS06120 fcf830bc76a3bc60ff15c601aab15747 774 Pfam PF02538 Hydantoinase B/oxoprolinase 44 601 1.2E-122 T 29-03-2018 IPR003692 Hydantoinase B/oxoprolinase GO:0003824 Reactome: R-HSA-174403 SMALA_RS24615 11a3137bb1df7131002db2dc20170208 145 Pfam PF07811 TadE-like protein 17 59 1.1E-8 T 29-03-2018 IPR012495 TadE-like SMALA_RS15120 d29c2e5eaa14282db5df23eb2bdf332d 341 SUPERFAMILY SSF63825 52 297 2.88E-5 T 29-03-2018 SMALA_RS07895 b3ab900e69dd464d9bc527a6b6ce57ed 71 Pfam PF04149 Domain of unknown function (DUF397) 14 64 1.4E-22 T 29-03-2018 IPR007278 Domain of unknown function DUF397 SMALA_RS36855 3d747d72a4f3c1f4e806c1a5c1c5f629 284 Pfam PF12679 ABC-2 family transporter protein 22 282 1.7E-11 T 29-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 SMALA_RS07775 97bc44c772f9449008bac9ae0f55c904 384 Gene3D G3DSA:3.30.70.270 36 211 2.9E-13 T 29-03-2018 SMALA_RS07775 97bc44c772f9449008bac9ae0f55c904 384 SUPERFAMILY SSF55073 44 171 2.67E-5 T 29-03-2018 IPR029787 Nucleotide cyclase SMALA_RS04850 c68060384c1909557747973b8552b8a5 168 Pfam PF12306 Inclusion body protein 4 164 3.2E-52 T 29-03-2018 IPR021087 Uncharacterised protein family PixA/AidA SMALA_RS13740 47e2c859c47a41382a678927c44211ef 69 Pfam PF04149 Domain of unknown function (DUF397) 7 62 2.4E-23 T 29-03-2018 IPR007278 Domain of unknown function DUF397 SMALA_RS18605 a20c8e84bd0fd5c4a9dd2a85f81d8902 153 Pfam PF07332 Putative Actinobacterial Holin-X, holin superfamily III 13 128 6.3E-28 T 29-03-2018 IPR009937 Putative Actinobacterial Holin-X, holin superfamily III SMALA_RS34130 9545000927c56145da321872cfa3213b 762 Gene3D G3DSA:2.60.40.650 666 760 4.7E-7 T 29-03-2018 SMALA_RS27540 47efff7cd9dc9a9fade71adc11f262f8 265 Pfam PF14581 SseB protein C-terminal domain 137 241 6.5E-16 T 29-03-2018 IPR027945 SseB protein, C-terminal SMALA_RS28010 292067b1885ccf7fed9d4a91f2d11a60 222 Pfam PF02620 Uncharacterized ACR, COG1399 81 199 1.5E-31 T 29-03-2018 IPR003772 Large ribosomal RNA subunit accumulation protein YceD SMALA_RS02830 d1402a5993270f81be074cde8d95d06c 253 Pfam PF01925 Sulfite exporter TauE/SafE 8 246 1.8E-27 T 29-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 SMALA_RS26930 100d34648bb6e842a8f7f7a610abb2fc 149 Pfam PF10739 Protein of unknown function (DUF2550) 12 143 3.4E-45 T 29-03-2018 IPR019675 Protein of unknown function DUF2550 SMALA_RS37155 33c1a45413dc97f5ed995b6118507ae1 243 Pfam PF04250 Protein of unknown function (DUF429) 23 232 2.1E-48 T 29-03-2018 IPR007362 Protein of unknown function DUF429 SMALA_RS39850 7eafd95ded6d32270809b82223fda51b 277 Pfam PF12730 ABC-2 family transporter protein 25 188 2.9E-7 T 29-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 SMALA_RS26260 a8fb324923bee0f3b338b1a88b0c815b 66 Pfam PF04149 Domain of unknown function (DUF397) 5 56 1.6E-11 T 29-03-2018 IPR007278 Domain of unknown function DUF397 SMALA_RS04040 792b21f3506398f2399de65a56b8a3bf 210 Pfam PF11139 Sap, sulfolipid-1-addressing protein 5 209 2.9E-33 T 29-03-2018 IPR021315 Glycolipid exporter Gap/Sap SMALA_RS25875 0a7a1d93cd774af3f3d4e27a267dcb73 201 Pfam PF05076 Suppressor of fused protein (SUFU) 29 194 8.3E-33 T 29-03-2018 IPR020941 Suppressor of fused-like domain Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5610787|Reactome: R-HSA-5632684 SMALA_RS36555 0d3559f7b12dce5ffcd769367f72f8de 242 Pfam PF14016 Protein of unknown function (DUF4232) 78 215 3.8E-25 T 29-03-2018 IPR025326 Protein of unknown function DUF4232 SMALA_RS29840 577278282145f2942fdfe124d2beea96 243 Pfam PF11452 Protein of unknown function (DUF3000) 26 224 3.4E-70 T 29-03-2018 IPR021555 Protein of unknown function DUF3000 SMALA_RS27830 8ecea3ef90832b9903841777662d1cf2 220 Pfam PF05331 Protein of unknown function (DUF742) 108 220 7.9E-41 T 29-03-2018 IPR007995 Protein of unknown function DUF742 SMALA_RS24075 d7e8122e095e22ccd5be550b1f7c28a2 162 Pfam PF14433 SUKH-3 immunity protein 9 153 7.7E-47 T 29-03-2018 IPR025850 SUKH-3 immunity protein SMALA_RS14130 813d5ddb9f091bd0cab50112b7caf25e 430 Pfam PF01757 Acyltransferase family 25 363 1.5E-17 T 29-03-2018 IPR002656 Acyltransferase 3 GO:0016747 SMALA_RS32285 b058d1a77bc18f9fe41b5516a54e93a2 244 Pfam PF07179 SseB protein N-terminal domain 22 143 2.3E-27 T 29-03-2018 IPR009839 SseB protein N-terminal domain SMALA_RS18855 ea543bbb5d6a99f7762f2528a5abbe8b 61 Pfam PF05122 Mobile element transfer protein 10 59 1.9E-29 T 29-03-2018 IPR007806 Mobile element transfer SMALA_RS00620 f5eb7c439e3c4efb66275df228d6aca6 405 Pfam PF09594 Glycosyltransferase family 87 68 304 4.9E-55 T 29-03-2018 IPR018584 Glycosyltransferase family 87 GO:0016758 SMALA_RS10100 02ad9b549ccd2ff2dfad5e3e4d08c9df 301 Pfam PF12698 ABC-2 family transporter protein 109 292 2.7E-10 T 29-03-2018 SMALA_RS43055 6d6716598539b551602831ba008b3670 747 Pfam PF03457 Helicase associated domain 389 445 7.3E-11 T 29-03-2018 IPR005114 Helicase-associated SMALA_RS43055 6d6716598539b551602831ba008b3670 747 Pfam PF03457 Helicase associated domain 536 589 3.7E-8 T 29-03-2018 IPR005114 Helicase-associated