locus-tag	class	description
HUT09_RS00130	COG4977	sequence-specific DNA binding
HUT09_RS00230	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT09_RS00235	COG0366	Alpha amylase catalytic
HUT09_RS00255	COG0456	acetyltransferase
HUT09_RS00280	COG0019	diaminopimelate decarboxylase activity
HUT09_RS00395	COG0714	Associated with various cellular activities
HUT09_RS00455	COG1309	transcriptional regulator
HUT09_RS00460	COG2409	Drug exporters of the RND superfamily
HUT09_RS00505	COG2205	protein histidine kinase activity
HUT09_RS00510	COG0745	RESPONSE REGULATOR receiver
HUT09_RS00585	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HUT09_RS00590	COG4106	trans-aconitate 2-methyltransferase activity
HUT09_RS00600	COG1846	Transcriptional regulator
HUT09_RS00605	COG1764	response to oxidative stress
HUT09_RS00620	COG1028	Short-chain dehydrogenase reductase Sdr
HUT09_RS00650	COG0277	FAD linked oxidase domain protein
HUT09_RS00660	COG1902	pentaerythritol trinitrate reductase activity
HUT09_RS00665	COG0640	Transcriptional regulator
HUT09_RS00670	COG1064	alcohol dehydrogenase
HUT09_RS00685	COG0702	epimerase
HUT09_RS00715	COG0642	Histidine kinase
HUT09_RS00735	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
HUT09_RS00745	COG0366	Alpha amylase catalytic
HUT09_RS00750	COG0395	ABC-type sugar transport system, permease component
HUT09_RS00755	COG1175	transmembrane transport
HUT09_RS00760	COG1653	transport
HUT09_RS00815	COG1349	DNA-binding transcription factor activity
HUT09_RS00820	COG1105	Belongs to the carbohydrate kinase PfkB family
HUT09_RS00830	COG0681	Belongs to the peptidase S26 family
HUT09_RS00850	COG0596	Alpha beta hydrolase
HUT09_RS00895	COG0254	rRNA binding
HUT09_RS00900	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HUT09_RS00960	COG1024	Enoyl-CoA hydratase
HUT09_RS00980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUT09_RS00985	COG0765	amino acid transport
HUT09_RS00995	COG0318	PFAM AMP-dependent synthetase and ligase
HUT09_RS01010	COG2072	flavoprotein involved in K transport
HUT09_RS01025	COG0318	PFAM AMP-dependent synthetase and ligase
HUT09_RS01030	COG2070	2-Nitropropane dioxygenase
HUT09_RS01035	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HUT09_RS01050	COG0515	serine threonine protein kinase
HUT09_RS01065	COG4221	oxidoreductase activity
HUT09_RS01075	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HUT09_RS01080	COG0346	lactoylglutathione lyase activity
HUT09_RS01095	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HUT09_RS01105	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HUT09_RS01105	COG3321	synthase
HUT09_RS01105	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUT09_RS01105	COG3321	synthase
HUT09_RS01105	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
HUT09_RS01105	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HUT09_RS01105	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUT09_RS01105	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
HUT09_RS01110	COG3321	synthase
HUT09_RS01110	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT09_RS01110	COG0318	PFAM AMP-dependent synthetase and ligase
HUT09_RS01110	COG0300	oxidoreductase activity
HUT09_RS01110	COG1028	Short-chain dehydrogenase reductase Sdr
HUT09_RS01115	COG1960	acyl-CoA dehydrogenase activity
HUT09_RS01120	COG2813	Specifically methylates the guanine in position
HUT09_RS01135	COG2356	endonuclease I
HUT09_RS01140	COG2066	Belongs to the glutaminase family
HUT09_RS01140	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
HUT09_RS01155	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HUT09_RS01160	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
HUT09_RS01175	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HUT09_RS01180	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
HUT09_RS01185	COG2080	2 iron, 2 sulfur cluster binding
HUT09_RS01245	COG2365	Tyrosine phosphatase family
HUT09_RS01270	COG1120	ATPase activity
HUT09_RS01275	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HUT09_RS01285	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT09_RS01295	COG0477	Major facilitator Superfamily
HUT09_RS01300	COG2382	esterase
HUT09_RS01305	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT09_RS01310	COG1028	Short-chain dehydrogenase reductase Sdr
HUT09_RS01315	COG1169	isochorismate synthase
HUT09_RS01320	COG1021	2,3-dihydroxybenzoate-AMP ligase
HUT09_RS01325	COG3433	isochorismatase activity
HUT09_RS01325	COG1535	isochorismatase
HUT09_RS01330	COG1535	isochorismatase
HUT09_RS01330	COG3433	isochorismatase activity
HUT09_RS01335	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HUT09_RS01410	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HUT09_RS01445	COG3845	ABC transporter
HUT09_RS01465	COG1470	cell adhesion involved in biofilm formation
HUT09_RS01485	COG1063	alcohol dehydrogenase
HUT09_RS01490	COG0395	ABC-type sugar transport system, permease component
HUT09_RS01505	COG1349	DNA-binding transcription factor activity
HUT09_RS01535	COG0589	response to stress
HUT09_RS01545	COG2382	esterase
HUT09_RS01550	COG1132	(ABC) transporter
HUT09_RS01560	COG1132	(ABC) transporter
HUT09_RS01565	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
HUT09_RS01570	COG1120	ATPase activity
HUT09_RS01575	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT09_RS01580	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT09_RS01585	COG3486	L-lysine 6-monooxygenase (NADPH) activity
HUT09_RS01605	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HUT09_RS01635	COG0640	Transcriptional regulator
HUT09_RS01670	COG1132	(ABC) transporter
HUT09_RS01695	COG1181	Belongs to the D-alanine--D-alanine ligase family
HUT09_RS01715	COG0504	CTP synthase activity
HUT09_RS01720	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HUT09_RS01725	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
HUT09_RS01735	COG0640	Transcriptional regulator
HUT09_RS01760	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HUT09_RS01765	COG0573	inorganic phosphate transmembrane transporter activity
HUT09_RS01770	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HUT09_RS01790	COG0640	Transcriptional regulator
HUT09_RS01805	COG2072	flavoprotein involved in K transport
HUT09_RS01810	COG0798	PFAM Bile acid sodium symporter
HUT09_RS01820	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HUT09_RS01825	COG2376	Dihydroxyacetone kinase
HUT09_RS01830	COG1461	Dihydroxyacetone kinase
HUT09_RS01845	COG0488	(ABC) transporter
HUT09_RS01875	COG1191	sigma factor activity
HUT09_RS01885	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HUT09_RS01890	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HUT09_RS01905	COG1120	ATPase activity
HUT09_RS01910	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT09_RS01935	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HUT09_RS01985	COG1295	ribonuclease BN
HUT09_RS01985	COG1959	2 iron, 2 sulfur cluster binding
HUT09_RS02020	COG1120	ATPase activity
HUT09_RS02025	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT09_RS02030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT09_RS02075	COG0366	Alpha amylase catalytic
HUT09_RS02075	COG1874	Beta-galactosidase
HUT09_RS02090	COG1609	Transcriptional regulator
HUT09_RS02095	COG1172	Belongs to the binding-protein-dependent transport system permease family
HUT09_RS02105	COG1129	ABC transporter
HUT09_RS02110	COG1879	ABC-type sugar transport system periplasmic component
HUT09_RS02140	COG0842	Transport permease protein
HUT09_RS02140	COG1131	(ABC) transporter
HUT09_RS02140	COG1716	ATPase activity
HUT09_RS02190	COG0328	RNA-DNA hybrid ribonuclease activity
HUT09_RS02195	COG1028	Short-chain dehydrogenase reductase Sdr
HUT09_RS02205	COG1132	(ABC) transporter
HUT09_RS02215	COG2264	protein methyltransferase activity
HUT09_RS02225	COG2207	Transcriptional regulator
HUT09_RS02225	COG4753	response regulator
HUT09_RS02230	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT09_RS02235	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT09_RS02240	COG1120	ATPase activity
HUT09_RS02255	COG1132	(ABC) transporter
HUT09_RS02280	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HUT09_RS02285	COG0477	Major facilitator Superfamily
HUT09_RS02335	COG0464	growth
HUT09_RS02345	COG1349	DNA-binding transcription factor activity
HUT09_RS02360	COG0702	epimerase
HUT09_RS02370	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HUT09_RS02385	COG1940	carbohydrate kinase activity
HUT09_RS02390	COG2223	nitrite transmembrane transporter activity
HUT09_RS02420	COG0445	tRNA wobble uridine modification
HUT09_RS02435	COG1660	Displays ATPase and GTPase activities
HUT09_RS02460	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
HUT09_RS02465	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
HUT09_RS02470	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
HUT09_RS02490	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HUT09_RS02495	COG2376	Dihydroxyacetone kinase
HUT09_RS02500	COG2376	Dihydroxyacetone kinase
HUT09_RS02505	COG0531	amino acid
HUT09_RS02515	COG1940	carbohydrate kinase activity
HUT09_RS02545	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
HUT09_RS02590	COG0584	glycerophosphoryl diester phosphodiesterase
HUT09_RS02595	COG0456	acetyltransferase
HUT09_RS02610	COG0671	phosphoesterase, PA-phosphatase related
HUT09_RS02635	COG2226	methyltransferase
HUT09_RS02660	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HUT09_RS02675	COG2706	6-phosphogluconolactonase activity
HUT09_RS02690	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HUT09_RS02695	COG0515	serine threonine protein kinase
HUT09_RS02695	COG2815	serine threonine protein kinase
HUT09_RS02700	COG0667	Aldo Keto reductase
HUT09_RS02705	COG3469	chitinase activity
HUT09_RS02740	COG1253	flavin adenine dinucleotide binding
HUT09_RS02775	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
HUT09_RS02780	COG0531	amino acid
HUT09_RS02785	COG2186	Transcriptional regulator
HUT09_RS02790	COG0174	glutamine synthetase
HUT09_RS02795	COG1012	belongs to the aldehyde dehydrogenase family
HUT09_RS02830	COG4981	capsule polysaccharide biosynthetic process
HUT09_RS02850	COG2835	tetraacyldisaccharide 4'-kinase activity
HUT09_RS02865	COG1802	Transcriptional regulator
HUT09_RS02875	COG0402	S-adenosylhomocysteine deaminase activity
HUT09_RS02890	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT09_RS02895	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT09_RS02900	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HUT09_RS02905	COG1132	(ABC) transporter
HUT09_RS02905	COG2375	cellular response to nickel ion
HUT09_RS02940	COG1357	PFAM Pentapeptide repeats (8 copies)
HUT09_RS02975	COG0546	phosphoglycolate phosphatase activity
HUT09_RS03015	COG1191	sigma factor activity
HUT09_RS03040	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HUT09_RS03055	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
HUT09_RS03060	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT09_RS03065	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT09_RS03075	COG4592	Periplasmic binding protein
HUT09_RS03110	COG2226	methyltransferase
HUT09_RS03135	COG2957	Belongs to the agmatine deiminase family
HUT09_RS03145	COG0444	Belongs to the ABC transporter superfamily
HUT09_RS03150	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HUT09_RS03160	COG0747	negative chemotaxis
HUT09_RS03165	COG2957	Belongs to the agmatine deiminase family
HUT09_RS03170	COG0804	urea catabolic process
HUT09_RS03175	COG0832	Belongs to the urease beta subunit family
HUT09_RS03175	COG0831	urea catabolic process
HUT09_RS03185	COG0515	serine threonine protein kinase
HUT09_RS03190	COG1309	transcriptional regulator
HUT09_RS03195	COG2957	Belongs to the agmatine deiminase family
HUT09_RS03220	COG2197	response regulator
HUT09_RS03225	COG0432	Pfam Uncharacterised protein family UPF0047
HUT09_RS03230	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HUT09_RS03235	COG1116	anion transmembrane transporter activity
HUT09_RS03245	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT09_RS03250	COG2072	flavoprotein involved in K transport
HUT09_RS03265	COG1132	(ABC) transporter
HUT09_RS03270	COG1846	Transcriptional regulator
HUT09_RS03275	COG0277	FAD linked oxidase domain protein
HUT09_RS03280	COG0673	inositol 2-dehydrogenase activity
HUT09_RS03285	COG1132	(ABC) transporter
HUT09_RS03290	COG1132	(ABC) transporter
HUT09_RS03315	COG1252	NADH dehydrogenase
HUT09_RS03320	COG1793	dna ligase
HUT09_RS03335	COG1946	Acyl-CoA thioesterase
HUT09_RS03345	COG3387	PFAM Glycoside hydrolase 15-related
HUT09_RS03370	COG0386	Belongs to the glutathione peroxidase family
HUT09_RS03375	COG1960	acyl-CoA dehydrogenase activity
HUT09_RS03385	COG0242	peptide deformylase activity
HUT09_RS03395	COG3442	glutamine amidotransferase
HUT09_RS03400	COG0205	6-phosphofructokinase activity
HUT09_RS03415	COG0204	Acyl-transferase
HUT09_RS03430	COG0829	nickel cation binding
HUT09_RS03435	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HUT09_RS03445	COG0804	urea catabolic process
HUT09_RS03450	COG0832	Belongs to the urease beta subunit family
HUT09_RS03455	COG0831	urea catabolic process
HUT09_RS03460	COG1309	transcriptional regulator
HUT09_RS03480	COG0740	serine-type endopeptidase activity
HUT09_RS03490	COG0791	NLP P60 protein
HUT09_RS03495	COG1280	lysine exporter protein (LysE YggA)
HUT09_RS03500	COG0583	DNA-binding transcription factor activity
HUT09_RS03525	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HUT09_RS03530	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HUT09_RS03535	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HUT09_RS03540	COG2226	methyltransferase
HUT09_RS03580	COG2814	Major facilitator Superfamily
HUT09_RS03810	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HUT09_RS03825	COG1940	carbohydrate kinase activity
HUT09_RS03830	COG2188	Transcriptional regulator
HUT09_RS03835	COG1595	DNA-templated transcription, initiation
HUT09_RS03850	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUT09_RS03875	COG0626	cystathionine gamma-synthase activity
HUT09_RS03900	COG1522	sequence-specific DNA binding
HUT09_RS03905	COG0419	ATPase involved in DNA repair
HUT09_RS03910	COG0420	3'-5' exonuclease activity
HUT09_RS03915	COG1739	Uncharacterized protein family UPF0029
HUT09_RS03920	COG1832	CoA-binding protein
HUT09_RS03965	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HUT09_RS03985	COG1968	undecaprenyl-diphosphatase activity
HUT09_RS04000	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HUT09_RS04050	COG2318	DinB family
HUT09_RS04065	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HUT09_RS04095	COG0492	ferredoxin-NADP+ reductase activity
HUT09_RS04130	COG0697	spore germination
HUT09_RS04170	COG1695	Transcriptional regulator
HUT09_RS04245	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HUT09_RS04245	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HUT09_RS04255	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HUT09_RS04275	COG1716	ATPase activity
HUT09_RS04295	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HUT09_RS04325	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HUT09_RS04335	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HUT09_RS04350	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HUT09_RS04380	COG2018	Roadblock/LC7 domain
HUT09_RS04445	COG2364	Membrane
HUT09_RS04455	COG2270	Major facilitator Superfamily
HUT09_RS04465	COG3030	protein affecting phage T7 exclusion by the F plasmid
HUT09_RS04470	COG1216	Glycosyl transferase, family 2
HUT09_RS04490	COG1960	acyl-CoA dehydrogenase activity
HUT09_RS04545	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
HUT09_RS04550	COG0140	phosphoribosyl-ATP diphosphatase activity
HUT09_RS04555	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
HUT09_RS04560	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HUT09_RS04560	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HUT09_RS04565	COG3201	nicotinamide mononucleotide transporter
HUT09_RS04595	COG0738	Major facilitator superfamily
HUT09_RS04600	COG2233	PERMEase
HUT09_RS04620	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HUT09_RS04630	COG1012	belongs to the aldehyde dehydrogenase family
HUT09_RS04645	COG2390	Transcriptional regulator
HUT09_RS04650	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HUT09_RS04660	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HUT09_RS04675	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HUT09_RS04685	COG1758	RNA polymerase activity
HUT09_RS04700	COG0284	orotidine-5'-phosphate decarboxylase activity
HUT09_RS04705	COG0167	dihydroorotate dehydrogenase activity
HUT09_RS04710	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HUT09_RS04715	COG0505	Belongs to the CarA family
HUT09_RS04725	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HUT09_RS04730	COG0540	Belongs to the ATCase OTCase family
HUT09_RS04735	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HUT09_RS04745	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HUT09_RS04750	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HUT09_RS04755	COG0006	proline dipeptidase activity
HUT09_RS04765	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
HUT09_RS04770	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HUT09_RS04775	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HUT09_RS04780	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HUT09_RS04790	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HUT09_RS04795	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HUT09_RS04815	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HUT09_RS04835	COG0124	histidyl-tRNA synthetase
HUT09_RS04850	COG1196	nuclear chromosome segregation
HUT09_RS04855	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HUT09_RS04860	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HUT09_RS04865	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HUT09_RS04870	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HUT09_RS04880	COG2255	four-way junction helicase activity
HUT09_RS04885	COG0632	four-way junction helicase activity
HUT09_RS04890	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
HUT09_RS04895	COG0217	transcriptional regulatory protein
HUT09_RS04900	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HUT09_RS04905	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HUT09_RS04915	COG0438	transferase activity, transferring glycosyl groups
HUT09_RS04920	COG1560	Kdo2-lipid A biosynthetic process
HUT09_RS04925	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HUT09_RS04950	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HUT09_RS04965	COG2176	DNA-directed DNA polymerase activity
HUT09_RS04965	COG5002	protein histidine kinase activity
HUT09_RS05025	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HUT09_RS05080	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HUT09_RS05080	COG1648	precorrin-2 dehydrogenase activity
HUT09_RS05085	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
HUT09_RS05100	COG1464	Belongs to the NlpA lipoprotein family
HUT09_RS05105	COG2011	ABC-type metal ion transport system permease component
HUT09_RS05145	COG0477	Major facilitator Superfamily
HUT09_RS05155	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUT09_RS05160	COG3973	AAA domain
HUT09_RS05170	COG0165	Argininosuccinate lyase
HUT09_RS05175	COG0137	argininosuccinate synthase activity
HUT09_RS05195	COG1438	arginine binding
HUT09_RS05200	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HUT09_RS05205	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HUT09_RS05210	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HUT09_RS05215	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HUT09_RS05225	COG0385	Bile acid
HUT09_RS05260	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HUT09_RS05275	COG0697	spore germination
HUT09_RS05285	COG1649	PFAM Uncharacterised BCR, COG1649
HUT09_RS05305	COG0072	phenylalanine-tRNA ligase activity
HUT09_RS05305	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HUT09_RS05310	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HUT09_RS05315	COG5002	protein histidine kinase activity
HUT09_RS05320	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HUT09_RS05325	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HUT09_RS05330	COG0291	Belongs to the bacterial ribosomal protein bL35 family
HUT09_RS05335	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HUT09_RS05395	COG4175	Glycine betaine
HUT09_RS05395	COG0517	IMP dehydrogenase activity
HUT09_RS05400	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HUT09_RS05445	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HUT09_RS05450	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HUT09_RS05490	COG0805	protein transport
HUT09_RS05495	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HUT09_RS05515	COG2378	regulation of single-species biofilm formation
HUT09_RS05525	COG0545	Peptidyl-prolyl cis-trans isomerase
HUT09_RS05530	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
HUT09_RS05540	COG1609	Transcriptional regulator
HUT09_RS05545	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
HUT09_RS05550	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
HUT09_RS05565	COG4122	O-methyltransferase activity
HUT09_RS05570	COG1222	aaa ATPase
HUT09_RS05590	COG0517	IMP dehydrogenase activity
HUT09_RS05590	COG1994	Peptidase M50
HUT09_RS05600	COG2197	response regulator
HUT09_RS05605	COG4166	transmembrane transport
HUT09_RS05615	COG0646	methionine synthase
HUT09_RS05615	COG1410	methionine synthase
HUT09_RS05620	COG1414	Transcriptional regulator
HUT09_RS05625	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HUT09_RS05630	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HUT09_RS05635	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HUT09_RS05640	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT09_RS05655	COG0215	cysteine-tRNA ligase activity
HUT09_RS05675	COG0598	Magnesium transport protein CorA
HUT09_RS05685	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT09_RS05690	COG0667	Aldo Keto reductase
HUT09_RS05720	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HUT09_RS05730	COG0564	pseudouridine synthase activity
HUT09_RS05745	COG2186	Transcriptional regulator
HUT09_RS05750	COG3265	gluconokinase activity
HUT09_RS05775	COG3573	Dehydrogenase
HUT09_RS05780	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
HUT09_RS05785	COG2149	membrane
HUT09_RS05800	COG4948	Mandelate Racemase Muconate Lactonizing
HUT09_RS05810	COG1960	acyl-CoA dehydrogenase activity
HUT09_RS05815	COG2234	aminopeptidase activity
HUT09_RS05815	COG4935	Belongs to the peptidase S8 family
HUT09_RS05825	COG0318	PFAM AMP-dependent synthetase and ligase
HUT09_RS05835	COG3876	Protein conserved in bacteria
HUT09_RS05910	COG1960	acyl-CoA dehydrogenase activity
HUT09_RS05920	COG0697	spore germination
HUT09_RS05925	COG2326	polyphosphate kinase activity
HUT09_RS05940	COG3842	ATPase activity
HUT09_RS05950	COG2851	Citrate transporter
HUT09_RS05955	COG0243	molybdopterin cofactor binding
HUT09_RS05960	COG1309	transcriptional regulator
HUT09_RS05965	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
HUT09_RS05970	COG2188	Transcriptional regulator
HUT09_RS05980	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HUT09_RS05990	COG2755	lipolytic protein G-D-S-L family
HUT09_RS06000	COG1725	Transcriptional regulator
HUT09_RS06015	COG2226	methyltransferase
HUT09_RS06035	COG4565	transcriptional regulatory protein
HUT09_RS06040	COG0456	acetyltransferase
HUT09_RS06070	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HUT09_RS06075	COG0587	DNA-directed DNA polymerase activity
HUT09_RS06115	COG0641	radical SAM
HUT09_RS06150	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT09_RS06155	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUT09_RS06175	COG0765	amino acid transport
HUT09_RS06180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUT09_RS06190	COG1799	cell septum assembly
HUT09_RS06195	COG1960	acyl-CoA dehydrogenase activity
HUT09_RS06200	COG0477	Major facilitator Superfamily
HUT09_RS06205	COG0671	phosphoesterase, PA-phosphatase related
HUT09_RS06220	COG0438	transferase activity, transferring glycosyl groups
HUT09_RS06235	COG1160	GTP binding
HUT09_RS06245	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
HUT09_RS06285	COG3541	Predicted nucleotidyltransferase
HUT09_RS06295	COG0494	nUDIX hydrolase
HUT09_RS06310	COG1187	pseudouridine synthase activity
HUT09_RS06315	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HUT09_RS06320	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HUT09_RS06335	COG0686	Belongs to the AlaDH PNT family
HUT09_RS06345	COG0494	nUDIX hydrolase
HUT09_RS06350	COG0504	CTP synthase activity
HUT09_RS06355	COG3387	PFAM Glycoside hydrolase 15-related
HUT09_RS06375	COG3119	arylsulfatase activity
HUT09_RS06380	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HUT09_RS06390	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HUT09_RS06395	COG0601	transmembrane transport
HUT09_RS06430	COG0497	DNA recombination
HUT09_RS06435	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HUT09_RS06455	COG1120	ATPase activity
HUT09_RS06460	COG0647	UMP catabolic process
HUT09_RS06490	COG2094	Belongs to the DNA glycosylase MPG family
HUT09_RS06500	COG1881	PFAM PEBP family protein
HUT09_RS06525	COG1119	ATPase activity
HUT09_RS06540	COG2197	response regulator
HUT09_RS06545	COG4585	Histidine kinase
HUT09_RS06555	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HUT09_RS06565	COG1131	(ABC) transporter
HUT09_RS06565	COG0842	Transport permease protein
HUT09_RS06565	COG1716	ATPase activity
HUT09_RS06570	COG0560	Phosphoserine phosphatase
HUT09_RS06570	COG3830	Belongs to the UPF0237 family
HUT09_RS06590	COG2186	Transcriptional regulator
HUT09_RS06600	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HUT09_RS06605	COG1028	Short-chain dehydrogenase reductase Sdr
HUT09_RS06620	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HUT09_RS06640	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HUT09_RS06645	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HUT09_RS06660	COG1063	alcohol dehydrogenase
HUT09_RS06695	COG3387	PFAM Glycoside hydrolase 15-related
HUT09_RS06735	COG1024	Enoyl-CoA hydratase
HUT09_RS06745	COG0488	(ABC) transporter
HUT09_RS06770	COG0235	Class ii aldolase
HUT09_RS06785	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
HUT09_RS06790	COG1492	cobalamin metabolic process
HUT09_RS06805	COG1797	cobyrinic acid a,c-diamide synthase activity
HUT09_RS06830	COG1104	cysteine desulfurase activity
HUT09_RS06845	COG1917	Cupin 2, conserved barrel domain protein
HUT09_RS06860	COG1902	pentaerythritol trinitrate reductase activity
HUT09_RS06865	COG1846	Transcriptional regulator
HUT09_RS06890	COG1414	Transcriptional regulator
HUT09_RS06905	COG4585	Histidine kinase
HUT09_RS06910	COG2197	response regulator
HUT09_RS06915	COG0768	penicillin binding
HUT09_RS06920	COG2252	PERMEase
HUT09_RS06935	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT09_RS06945	COG0431	NADPH-dependent FMN reductase
HUT09_RS06960	COG0583	DNA-binding transcription factor activity
HUT09_RS06970	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HUT09_RS07000	COG0515	serine threonine protein kinase
HUT09_RS07000	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HUT09_RS07020	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HUT09_RS07025	COG2171	N-acyltransferase activity
HUT09_RS07030	COG3226	Transcriptional regulator
HUT09_RS07050	COG2151	metal-sulfur cluster biosynthetic enzyme
HUT09_RS07055	COG0822	iron-sulfur transferase activity
HUT09_RS07060	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HUT09_RS07065	COG0396	ATPase activity
HUT09_RS07075	COG0719	Fe-S assembly protein
HUT09_RS07090	COG1131	(ABC) transporter
HUT09_RS07110	COG0109	protoheme IX farnesyltransferase activity
HUT09_RS07120	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HUT09_RS07135	COG0363	glucosamine-6-phosphate deaminase activity
HUT09_RS07145	COG4195	phage-related replication protein
HUT09_RS07160	COG0166	Belongs to the GPI family
HUT09_RS07170	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HUT09_RS07175	COG0149	triose-phosphate isomerase activity
HUT09_RS07180	COG0126	phosphoglycerate kinase activity
HUT09_RS07185	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HUT09_RS07190	COG1481	regulation of sporulation
HUT09_RS07195	COG0391	Required for morphogenesis under gluconeogenic growth conditions
HUT09_RS07200	COG1660	Displays ATPase and GTPase activities
HUT09_RS07205	COG0322	excinuclease ABC activity
HUT09_RS07230	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HUT09_RS07260	COG0556	nucleotide-excision repair
HUT09_RS07270	COG0584	glycerophosphoryl diester phosphodiesterase
HUT09_RS07275	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HUT09_RS07285	COG2814	Major facilitator Superfamily
HUT09_RS07295	COG2313	pseudouridylate synthase activity
HUT09_RS07315	COG0436	Aminotransferase
HUT09_RS07335	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HUT09_RS07355	COG0237	dephospho-CoA kinase activity
HUT09_RS07375	COG2226	methyltransferase
HUT09_RS07380	COG1643	Atp-dependent helicase
HUT09_RS07415	COG2050	protein possibly involved in aromatic compounds catabolism
HUT09_RS07470	COG0737	Belongs to the 5'-nucleotidase family
HUT09_RS07490	COG0659	secondary active sulfate transmembrane transporter activity
HUT09_RS07500	COG2824	Alkylphosphonate utilization operon protein PhnA
HUT09_RS07520	COG1605	Chorismate mutase
HUT09_RS07520	COG0287	Prephenate dehydrogenase
HUT09_RS07555	COG1028	Short-chain dehydrogenase reductase Sdr
HUT09_RS07560	COG1024	Enoyl-CoA hydratase
HUT09_RS07585	COG1278	Cold shock
HUT09_RS07590	COG0183	Belongs to the thiolase family
HUT09_RS07595	COG1309	transcriptional regulator
HUT09_RS07600	COG1028	Short-chain dehydrogenase reductase Sdr
HUT09_RS07605	COG1960	acyl-CoA dehydrogenase activity
HUT09_RS07610	COG1960	acyl-CoA dehydrogenase activity
HUT09_RS07625	COG2304	oxidoreductase activity
HUT09_RS07630	COG0705	Rhomboid family
HUT09_RS07640	COG0069	glutamate synthase activity
HUT09_RS07640	COG0070	glutamate synthase
HUT09_RS07640	COG0067	glutamate synthase
HUT09_RS07650	COG1397	ADP-ribosylglycohydrolase
HUT09_RS07670	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUT09_RS07675	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HUT09_RS07685	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HUT09_RS07695	COG0159	tryptophan synthase activity
HUT09_RS07700	COG0133	tryptophan synthase activity
HUT09_RS07710	COG0134	indole-3-glycerol-phosphate synthase activity
HUT09_RS07730	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HUT09_RS07735	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HUT09_RS07745	COG2508	Transcriptional regulator
HUT09_RS07760	COG0107	imidazoleglycerol-phosphate synthase activity
HUT09_RS07765	COG0251	oxidation-reduction process
HUT09_RS07770	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HUT09_RS07775	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HUT09_RS07785	COG0131	Imidazoleglycerol-phosphate dehydratase
HUT09_RS07790	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HUT09_RS07795	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HUT09_RS07835	COG1432	Conserved Protein
HUT09_RS07845	COG0587	DNA-directed DNA polymerase activity
HUT09_RS07895	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HUT09_RS07905	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HUT09_RS07910	COG3599	regulation of cell shape
HUT09_RS07920	COG1799	cell septum assembly
HUT09_RS07925	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HUT09_RS07945	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HUT09_RS07955	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HUT09_RS07960	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HUT09_RS07970	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HUT09_RS07975	COG0768	penicillin binding
HUT09_RS07985	COG0275	rRNA processing
HUT09_RS07995	COG0714	Associated with various cellular activities
HUT09_RS08015	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HUT09_RS08025	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
HUT09_RS08030	COG1511	domain protein
HUT09_RS08060	COG0352	thiamine-phosphate diphosphorylase activity
HUT09_RS08080	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HUT09_RS08080	COG2022	thiamine diphosphate biosynthetic process
HUT09_RS08090	COG2022	thiamine diphosphate biosynthetic process
HUT09_RS08095	COG0515	serine threonine protein kinase
HUT09_RS08095	COG2815	serine threonine protein kinase
HUT09_RS08100	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HUT09_RS08105	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HUT09_RS08110	COG2193	ferroxidase activity
HUT09_RS08120	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
HUT09_RS08135	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HUT09_RS08145	COG4585	Histidine kinase
HUT09_RS08170	COG1940	carbohydrate kinase activity
HUT09_RS08180	COG0003	Pfam Anion-transporting ATPase
HUT09_RS08245	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HUT09_RS08250	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HUT09_RS08255	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HUT09_RS08260	COG0723	plastoquinol--plastocyanin reductase activity
HUT09_RS08265	COG2010	Cytochrome c
HUT09_RS08270	COG1845	cytochrome c oxidase, subunit III
HUT09_RS08280	COG1376	ErfK ybiS ycfS ynhG family protein
HUT09_RS08290	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HUT09_RS08295	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HUT09_RS08300	COG1104	cysteine desulfurase activity
HUT09_RS08305	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUT09_RS08325	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HUT09_RS08335	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HUT09_RS08340	COG2197	response regulator
HUT09_RS08345	COG4585	Histidine kinase
HUT09_RS08365	COG4106	trans-aconitate 2-methyltransferase activity
HUT09_RS08370	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HUT09_RS08385	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
HUT09_RS08390	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HUT09_RS08390	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
HUT09_RS08405	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
HUT09_RS08410	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HUT09_RS08415	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HUT09_RS08430	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
HUT09_RS08450	COG1090	epimerase
HUT09_RS08465	COG0321	lipoyl(octanoyl) transferase activity
HUT09_RS08470	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HUT09_RS08500	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HUT09_RS08520	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HUT09_RS08525	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUT09_RS08550	COG0745	RESPONSE REGULATOR receiver
HUT09_RS08555	COG2409	Drug exporters of the RND superfamily
HUT09_RS08560	COG4585	Histidine kinase
HUT09_RS08565	COG2197	response regulator
HUT09_RS08625	COG0366	Alpha amylase catalytic
HUT09_RS08630	COG3833	ABC-type maltose transport systems, permease component
HUT09_RS08645	COG1609	Transcriptional regulator
HUT09_RS08660	COG0531	amino acid
HUT09_RS08670	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
HUT09_RS08680	COG2890	protein-(glutamine-N5) methyltransferase activity
HUT09_RS08690	COG0477	Major facilitator Superfamily
HUT09_RS08695	COG1309	transcriptional regulator
HUT09_RS08720	COG0174	glutamine synthetase
HUT09_RS08745	COG2132	Multicopper oxidase
HUT09_RS08750	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HUT09_RS08750	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
HUT09_RS08755	COG2814	Major facilitator Superfamily
HUT09_RS08770	COG0477	Major facilitator Superfamily
HUT09_RS08775	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
HUT09_RS08795	COG1994	Peptidase M50
HUT09_RS08855	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HUT09_RS08860	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT09_RS08865	COG1120	ATPase activity
HUT09_RS08885	COG1834	amidinotransferase
HUT09_RS08900	COG2814	Major facilitator Superfamily
HUT09_RS08910	COG3540	Alkaline phosphatase
HUT09_RS08915	COG1028	Short-chain dehydrogenase reductase Sdr
HUT09_RS08925	COG0384	phenazine biosynthesis protein PhzF
HUT09_RS08955	COG0456	acetyltransferase
HUT09_RS08985	COG0557	exoribonuclease II activity
HUT09_RS08990	COG3022	response to hydroperoxide
HUT09_RS08995	COG0800	Aldolase
HUT09_RS09015	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HUT09_RS09035	COG1028	Short-chain dehydrogenase reductase Sdr
HUT09_RS09045	COG2030	dehydratase
HUT09_RS09055	COG0183	Belongs to the thiolase family
HUT09_RS09060	COG1960	acyl-CoA dehydrogenase activity
HUT09_RS09065	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HUT09_RS09065	COG2146	nitrite reductase [NAD(P)H] activity
HUT09_RS09070	COG0446	pyridine nucleotide-disulphide oxidoreductase
HUT09_RS09075	COG0243	molybdopterin cofactor binding
HUT09_RS09080	COG2223	nitrite transmembrane transporter activity
HUT09_RS09085	COG0477	Major facilitator Superfamily
HUT09_RS09105	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT09_RS09135	COG0438	transferase activity, transferring glycosyl groups
HUT09_RS09140	COG1309	transcriptional regulator
HUT09_RS09210	COG3845	ABC transporter
HUT09_RS09220	COG0183	Belongs to the thiolase family
HUT09_RS09225	COG2124	cytochrome p450
HUT09_RS09260	COG0390	transport system, permease component
HUT09_RS09275	COG2259	Doxx family
HUT09_RS09355	COG1358	cellular component organization or biogenesis
HUT09_RS09400	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
HUT09_RS09410	COG0477	Major facilitator Superfamily
HUT09_RS09415	COG1309	transcriptional regulator
HUT09_RS09430	COG4585	Histidine kinase
HUT09_RS09435	COG2197	response regulator
HUT09_RS09450	COG0667	Aldo Keto reductase
HUT09_RS09455	COG0789	Transcriptional regulator
HUT09_RS09480	COG1741	Belongs to the pirin family
HUT09_RS09495	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HUT09_RS09500	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUT09_RS09505	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HUT09_RS09535	COG1309	transcriptional regulator
HUT09_RS09540	COG1280	lysine exporter protein (LysE YggA)
HUT09_RS09550	COG1764	response to oxidative stress
HUT09_RS09555	COG2130	NADP-dependent
HUT09_RS09585	COG1522	sequence-specific DNA binding
HUT09_RS09600	COG3291	Pkd domain containing protein
HUT09_RS09605	COG0318	PFAM AMP-dependent synthetase and ligase
HUT09_RS09610	COG0825	malonyl-CoA metabolic process
HUT09_RS09610	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HUT09_RS09615	COG1309	transcriptional regulator
HUT09_RS09620	COG1028	Short-chain dehydrogenase reductase Sdr
HUT09_RS09635	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT09_RS09650	COG0154	amidase activity
HUT09_RS09670	COG1960	acyl-CoA dehydrogenase activity
HUT09_RS09690	COG1028	Short-chain dehydrogenase reductase Sdr
HUT09_RS09695	COG2175	clavaminate synthase activity
HUT09_RS09705	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT09_RS09770	COG1070	Carbohydrate kinase
HUT09_RS09790	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HUT09_RS09795	COG0358	DNA primase activity
HUT09_RS09800	COG2226	methyltransferase
HUT09_RS09810	COG0477	Major facilitator Superfamily
HUT09_RS09820	COG0232	Belongs to the dGTPase family. Type 2 subfamily
HUT09_RS09830	COG2949	membrane
HUT09_RS09835	COG0243	molybdopterin cofactor binding
HUT09_RS09880	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HUT09_RS09885	COG2146	nitrite reductase [NAD(P)H] activity
HUT09_RS09885	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HUT09_RS09910	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HUT09_RS09910	COG0574	Belongs to the PEP-utilizing enzyme family
HUT09_RS09920	COG3842	ATPase activity
HUT09_RS09925	COG2011	ABC-type metal ion transport system permease component
HUT09_RS09940	COG2188	Transcriptional regulator
HUT09_RS09955	COG1191	sigma factor activity
HUT09_RS09970	COG0667	Aldo Keto reductase
HUT09_RS09990	COG0477	Major facilitator Superfamily
HUT09_RS10010	COG2226	methyltransferase
HUT09_RS10015	COG2318	DinB family
HUT09_RS10020	COG2066	Belongs to the glutaminase family
HUT09_RS10030	COG3655	Transcriptional regulator
HUT09_RS10050	COG2267	carboxylic ester hydrolase activity
HUT09_RS10065	COG0784	Response regulator, receiver
HUT09_RS10070	COG4251	negative regulation of phosphorylation
HUT09_RS10075	COG2204	response regulator
HUT09_RS10175	COG4221	oxidoreductase activity
HUT09_RS10205	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HUT09_RS10215	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HUT09_RS10230	COG0423	glycine-tRNA ligase activity
HUT09_RS10240	COG1121	(ABC) transporter
HUT09_RS10245	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HUT09_RS10255	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HUT09_RS10260	COG1381	Involved in DNA repair and RecF pathway recombination
HUT09_RS10275	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HUT09_RS10290	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HUT09_RS10310	COG2315	Protein conserved in bacteria
HUT09_RS10320	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HUT09_RS10330	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUT09_RS10340	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HUT09_RS10345	COG1234	tRNA 3'-trailer cleavage
HUT09_RS10350	COG0537	adenosine 5'-monophosphoramidase activity
HUT09_RS10365	COG0484	heat shock protein binding
HUT09_RS10370	COG1420	regulation of RNA biosynthetic process
HUT09_RS10400	COG1022	Amp-dependent synthetase and ligase
HUT09_RS10405	COG0481	GTPase activity
HUT09_RS10410	COG0268	Binds directly to 16S ribosomal RNA
HUT09_RS10445	COG1555	photosystem II stabilization
HUT09_RS10450	COG1307	EDD domain protein, DegV family
HUT09_RS10460	COG0495	leucyl-tRNA aminoacylation
HUT09_RS10495	COG0588	phosphoglycerate mutase activity
HUT09_RS10500	COG0799	negative regulation of ribosome biogenesis
HUT09_RS10510	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HUT09_RS10525	COG0501	Belongs to the peptidase M48B family
HUT09_RS10540	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HUT09_RS10550	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HUT09_RS10555	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HUT09_RS10575	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HUT09_RS10580	COG0211	Belongs to the bacterial ribosomal protein bL27 family
HUT09_RS10585	COG0261	This protein binds to 23S rRNA in the presence of protein L20
HUT09_RS10620	COG0673	inositol 2-dehydrogenase activity
HUT09_RS10630	COG1530	ribonuclease E activity
HUT09_RS10655	COG0772	Belongs to the SEDS family
HUT09_RS10675	COG1077	Cell shape determining protein MreB Mrl
HUT09_RS10680	COG0105	UTP biosynthetic process
HUT09_RS10690	COG0285	dihydrofolate synthase activity
HUT09_RS10695	COG0525	valine-tRNA ligase activity
HUT09_RS10705	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HUT09_RS10710	COG0740	serine-type endopeptidase activity
HUT09_RS10715	COG0740	serine-type endopeptidase activity
HUT09_RS10720	COG0544	peptidyl-prolyl cis-trans isomerase activity
HUT09_RS10740	COG3594	Acyltransferase
HUT09_RS10750	COG0475	glutathione-regulated potassium exporter activity
HUT09_RS10760	COG4552	Acetyltransferase involved in intracellular survival and related
HUT09_RS10775	COG1113	amino acid transport
HUT09_RS10780	COG1268	BioY protein
HUT09_RS10785	COG1113	amino acid transport
HUT09_RS10790	COG1113	amino acid transport
HUT09_RS10800	COG0584	glycerophosphoryl diester phosphodiesterase
HUT09_RS10805	COG0783	Belongs to the Dps family
HUT09_RS10810	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HUT09_RS10815	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HUT09_RS10820	COG0640	Transcriptional regulator
HUT09_RS10830	COG0110	maltose O-acetyltransferase activity
HUT09_RS10850	COG2211	Major facilitator Superfamily
HUT09_RS10860	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
HUT09_RS10895	COG4266	Belongs to the allantoicase family
HUT09_RS10900	COG0583	DNA-binding transcription factor activity
HUT09_RS10920	COG3291	Pkd domain containing protein
HUT09_RS10920	COG3525	Glycosyl hydrolase, family 20, catalytic domain
HUT09_RS10930	COG0668	transmembrane transport
HUT09_RS10935	COG1940	carbohydrate kinase activity
HUT09_RS10945	COG1175	transmembrane transport
HUT09_RS10950	COG0395	ABC-type sugar transport system, permease component
HUT09_RS10955	COG1486	melibiose metabolic process
HUT09_RS10970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUT09_RS11000	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HUT09_RS11005	COG2346	COG2346, Truncated hemoglobins
HUT09_RS11030	COG0629	single-stranded DNA binding
HUT09_RS11075	COG1131	(ABC) transporter
HUT09_RS11095	COG3962	Belongs to the TPP enzyme family
HUT09_RS11100	COG3718	enzyme involved in inositol metabolism
HUT09_RS11115	COG1082	Xylose isomerase domain protein TIM barrel
HUT09_RS11120	COG2318	DinB family
HUT09_RS11135	COG2409	Drug exporters of the RND superfamily
HUT09_RS11160	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HUT09_RS11235	COG0673	inositol 2-dehydrogenase activity
HUT09_RS11240	COG1609	Transcriptional regulator
HUT09_RS11265	COG0515	serine threonine protein kinase
HUT09_RS11300	COG1404	Belongs to the peptidase S8 family
HUT09_RS11315	COG1472	Belongs to the glycosyl hydrolase 3 family
HUT09_RS11340	COG0028	Belongs to the TPP enzyme family
HUT09_RS11350	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HUT09_RS11455	COG1946	Acyl-CoA thioesterase
HUT09_RS11475	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
HUT09_RS11475	COG2755	lipolytic protein G-D-S-L family
HUT09_RS11490	COG2311	Membrane
HUT09_RS11500	COG1309	transcriptional regulator
HUT09_RS11505	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HUT09_RS11520	COG1960	acyl-CoA dehydrogenase activity
HUT09_RS11540	COG1733	regulation of RNA biosynthetic process
HUT09_RS11560	COG0076	glutamate decarboxylase activity
HUT09_RS11565	COG3486	L-lysine 6-monooxygenase (NADPH) activity
HUT09_RS11595	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HUT09_RS11600	COG0589	response to stress
HUT09_RS11605	COG4977	sequence-specific DNA binding
HUT09_RS11620	COG3397	chitin binding
HUT09_RS11640	COG0395	ABC-type sugar transport system, permease component
HUT09_RS11655	COG2985	domain, Protein
HUT09_RS11660	COG2985	domain, Protein
HUT09_RS11670	COG3693	PFAM glycoside hydrolase, family 10
HUT09_RS11670	COG3509	depolymerase
HUT09_RS11755	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT09_RS11770	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUT09_RS11775	COG0765	amino acid transport
HUT09_RS11780	COG0765	amino acid transport
HUT09_RS11785	COG1126	abc transporter atp-binding protein
HUT09_RS11800	COG0318	PFAM AMP-dependent synthetase and ligase
HUT09_RS11805	COG3397	chitin binding
HUT09_RS11885	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HUT09_RS11890	COG2188	Transcriptional regulator
HUT09_RS11915	COG0673	inositol 2-dehydrogenase activity
HUT09_RS11920	COG4702	Belongs to the UPF0303 family
HUT09_RS11930	COG0706	membrane insertase activity
HUT09_RS11930	COG4455	Protein of avirulence locus involved in temperature-dependent protein secretion
HUT09_RS11940	COG3764	Sortase (surface protein transpeptidase)
HUT09_RS12000	COG0583	DNA-binding transcription factor activity
HUT09_RS12045	COG2267	carboxylic ester hydrolase activity
HUT09_RS12060	COG0697	spore germination
HUT09_RS12070	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT09_RS12080	COG2313	pseudouridylate synthase activity
HUT09_RS12085	COG2733	membrane
HUT09_RS12115	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HUT09_RS12140	COG0477	Major facilitator Superfamily
HUT09_RS12150	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HUT09_RS12160	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HUT09_RS12165	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HUT09_RS12170	COG1263	PTS System
HUT09_RS12175	COG1263	PTS System
HUT09_RS12180	COG1234	tRNA 3'-trailer cleavage
HUT09_RS12200	COG1120	ATPase activity
HUT09_RS12205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT09_RS12220	COG1113	amino acid transport
HUT09_RS12230	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
HUT09_RS12240	COG1335	isochorismatase
HUT09_RS12275	COG0277	FAD linked oxidase domain protein
HUT09_RS12285	COG3185	4-Hydroxyphenylpyruvate dioxygenase
HUT09_RS12295	COG1174	glycine betaine transport
HUT09_RS12305	COG1174	glycine betaine transport
HUT09_RS12310	COG1732	Glycine betaine
HUT09_RS12330	COG3480	Lon protease (S16) C-terminal proteolytic domain
HUT09_RS12345	COG3654	unkown
HUT09_RS12385	COG3525	Glycosyl hydrolase, family 20, catalytic domain
HUT09_RS12390	COG0395	ABC-type sugar transport system, permease component
HUT09_RS12410	COG1678	Uncharacterized ACR, COG1678
HUT09_RS12415	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HUT09_RS12430	COG0776	regulation of translation
HUT09_RS12440	COG3973	AAA domain
HUT09_RS12440	COG3973	AAA domain
HUT09_RS12465	COG2223	nitrite transmembrane transporter activity
HUT09_RS12485	COG0583	DNA-binding transcription factor activity
HUT09_RS12505	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HUT09_RS12510	COG0793	Belongs to the peptidase S41A family
HUT09_RS12515	COG2177	Part of the ABC transporter FtsEX involved in
HUT09_RS12520	COG2884	Cell division ATP-binding protein ftsE
HUT09_RS12535	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HUT09_RS12540	COG0515	serine threonine protein kinase
HUT09_RS12545	COG0515	serine threonine protein kinase
HUT09_RS12555	COG1653	transport
HUT09_RS12560	COG1175	transmembrane transport
HUT09_RS12565	COG0395	ABC-type sugar transport system, permease component
HUT09_RS12570	COG0463	Glycosyl transferase, family 2
HUT09_RS12570	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HUT09_RS12575	COG0438	transferase activity, transferring glycosyl groups
HUT09_RS12580	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HUT09_RS12585	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HUT09_RS12595	COG1073	alpha beta
HUT09_RS12595	COG2226	methyltransferase
HUT09_RS12600	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HUT09_RS12605	COG1216	Glycosyl transferase, family 2
HUT09_RS12615	COG1309	transcriptional regulator
HUT09_RS12625	COG1134	teichoic acid transport
HUT09_RS12630	COG2902	Dehydrogenase
HUT09_RS12655	COG0653	protein targeting
HUT09_RS12670	COG2197	response regulator
HUT09_RS12675	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HUT09_RS12685	COG0823	Involved in the tonB-independent uptake of proteins
HUT09_RS12690	COG5000	phosphorelay sensor kinase activity
HUT09_RS12690	COG5002	protein histidine kinase activity
HUT09_RS12695	COG0745	RESPONSE REGULATOR receiver
HUT09_RS12700	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HUT09_RS12720	COG0714	Associated with various cellular activities
HUT09_RS12760	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
HUT09_RS12780	COG2835	tetraacyldisaccharide 4'-kinase activity
HUT09_RS12785	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HUT09_RS12820	COG0391	Required for morphogenesis under gluconeogenic growth conditions
HUT09_RS12825	COG0778	Nitroreductase
HUT09_RS12825	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
HUT09_RS12835	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HUT09_RS12850	COG1316	TRANSCRIPTIONal
HUT09_RS12855	COG1316	TRANSCRIPTIONal
HUT09_RS12870	COG1316	TRANSCRIPTIONal
HUT09_RS12880	COG1316	TRANSCRIPTIONal
HUT09_RS12920	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HUT09_RS12955	COG2205	protein histidine kinase activity
HUT09_RS12960	COG0745	RESPONSE REGULATOR receiver
HUT09_RS12965	COG3104	oligopeptide transport
HUT09_RS12995	COG1366	Belongs to the anti-sigma-factor antagonist family
HUT09_RS13000	COG1191	sigma factor activity
HUT09_RS13005	COG1228	amidohydrolase
HUT09_RS13020	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HUT09_RS13070	COG2755	lipolytic protein G-D-S-L family
HUT09_RS13075	COG0183	Belongs to the thiolase family
HUT09_RS13100	COG0577	efflux transmembrane transporter activity
HUT09_RS13100	COG1136	(ABC) transporter
HUT09_RS13105	COG0577	efflux transmembrane transporter activity
HUT09_RS13105	COG1136	(ABC) transporter
HUT09_RS13110	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HUT09_RS13115	COG1252	NADH dehydrogenase
HUT09_RS13135	COG0148	phosphopyruvate hydratase activity
HUT09_RS13150	COG2124	cytochrome p450
HUT09_RS13170	COG0515	serine threonine protein kinase
HUT09_RS13170	COG2815	serine threonine protein kinase
HUT09_RS13190	COG1335	isochorismatase
HUT09_RS13320	COG3903	Transcriptional regulator
HUT09_RS13320	COG3629	intracellular signal transduction
HUT09_RS13330	COG0577	efflux transmembrane transporter activity
HUT09_RS13335	COG1136	(ABC) transporter
HUT09_RS13345	COG2814	Major facilitator Superfamily
HUT09_RS13390	COG2124	cytochrome p450
HUT09_RS13420	COG4585	Histidine kinase
HUT09_RS13435	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HUT09_RS13440	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HUT09_RS13445	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HUT09_RS13450	COG0193	aminoacyl-tRNA hydrolase activity
HUT09_RS13460	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HUT09_RS13485	COG4106	trans-aconitate 2-methyltransferase activity
HUT09_RS13495	COG2197	response regulator
HUT09_RS13505	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HUT09_RS13520	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HUT09_RS13550	COG0488	(ABC) transporter
HUT09_RS13555	COG2161	toxin-antitoxin pair type II binding
HUT09_RS13560	COG4115	mRNA cleavage
HUT09_RS13575	COG2813	Specifically methylates the guanine in position
HUT09_RS13580	COG2318	DinB family
HUT09_RS13585	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HUT09_RS13590	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HUT09_RS13600	COG0084	hydrolase, TatD family'
HUT09_RS13630	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HUT09_RS13680	COG0442	prolyl-tRNA aminoacylation
HUT09_RS13715	COG1028	Short-chain dehydrogenase reductase Sdr
HUT09_RS13720	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HUT09_RS13725	COG1122	ATPase activity
HUT09_RS13735	COG0310	cobalt ion transport
HUT09_RS13745	COG1846	Transcriptional regulator
HUT09_RS13765	COG2409	Drug exporters of the RND superfamily
HUT09_RS13775	COG4946	Tricorn protease homolog
HUT09_RS13775	COG0793	Belongs to the peptidase S41A family
HUT09_RS13795	COG1028	Short-chain dehydrogenase reductase Sdr
HUT09_RS13805	COG2072	flavoprotein involved in K transport
HUT09_RS13815	COG0708	Exodeoxyribonuclease III
HUT09_RS13825	COG2340	Cysteine-rich secretory protein family
HUT09_RS13855	COG0521	Mo-molybdopterin cofactor biosynthetic process
HUT09_RS13860	COG0315	cyclic pyranopterin monophosphate synthase activity
HUT09_RS13870	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HUT09_RS13875	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HUT09_RS13885	COG3263	regulation of cellular component size
HUT09_RS13900	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HUT09_RS13910	COG1970	mechanosensitive ion channel activity
HUT09_RS13930	COG0437	4 iron, 4 sulfur cluster binding
HUT09_RS13935	COG0243	molybdopterin cofactor binding
HUT09_RS13955	COG0477	Major facilitator Superfamily
HUT09_RS13975	COG3384	dioxygenase
HUT09_RS13980	COG1846	Transcriptional regulator
HUT09_RS14045	COG1686	Belongs to the peptidase S11 family
HUT09_RS14105	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
HUT09_RS14120	COG0768	penicillin binding
HUT09_RS14180	COG0667	Aldo Keto reductase
HUT09_RS14190	COG3866	Pectate lyase
HUT09_RS14195	COG1653	transport
HUT09_RS14210	COG0395	ABC-type sugar transport system, permease component
HUT09_RS14230	COG1802	Transcriptional regulator
HUT09_RS14235	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HUT09_RS14285	COG0183	Belongs to the thiolase family
HUT09_RS14290	COG1028	Short-chain dehydrogenase reductase Sdr
HUT09_RS14305	COG1309	transcriptional regulator
HUT09_RS14335	COG0318	PFAM AMP-dependent synthetase and ligase
HUT09_RS14365	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
HUT09_RS14380	COG0163	prenyltransferase activity
HUT09_RS14390	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
HUT09_RS14395	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HUT09_RS14405	COG1012	belongs to the aldehyde dehydrogenase family
HUT09_RS14410	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HUT09_RS14415	COG1333	cytochrome c biogenesis protein
HUT09_RS14420	COG0785	Cytochrome C biogenesis protein
HUT09_RS14435	COG2382	esterase
HUT09_RS14440	COG0406	alpha-ribazole phosphatase activity
HUT09_RS14445	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
HUT09_RS14475	COG1116	anion transmembrane transporter activity
HUT09_RS14490	COG1690	Belongs to the RtcB family
HUT09_RS14510	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
HUT09_RS14515	COG0018	arginyl-trna synthetase
HUT09_RS14550	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HUT09_RS14570	COG0113	porphobilinogen synthase activity
HUT09_RS14575	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HUT09_RS14575	COG1648	precorrin-2 dehydrogenase activity
HUT09_RS14580	COG0181	hydroxymethylbilane synthase activity
HUT09_RS14585	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HUT09_RS14590	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HUT09_RS14645	COG2223	nitrite transmembrane transporter activity
HUT09_RS14650	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HUT09_RS14670	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HUT09_RS14680	COG0842	Transport permease protein
HUT09_RS14680	COG1129	ABC transporter
HUT09_RS14690	COG4991	sh3 domain protein
HUT09_RS14700	COG0129	dihydroxy-acid dehydratase activity
HUT09_RS14705	COG1309	transcriptional regulator
HUT09_RS14710	COG1082	Xylose isomerase domain protein TIM barrel
HUT09_RS14715	COG0248	Ppx GppA phosphatase
HUT09_RS14735	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
HUT09_RS14745	COG1194	a g-specific adenine glycosylase
HUT09_RS14750	COG1595	DNA-templated transcription, initiation
HUT09_RS14760	COG0745	RESPONSE REGULATOR receiver
HUT09_RS14765	COG2205	protein histidine kinase activity
HUT09_RS14770	COG0739	heme binding
HUT09_RS14800	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HUT09_RS14820	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HUT09_RS14830	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HUT09_RS14835	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HUT09_RS14860	COG2197	response regulator
HUT09_RS14875	COG0649	NAD binding
HUT09_RS14885	COG1732	Glycine betaine
HUT09_RS14890	COG1174	glycine betaine transport
HUT09_RS14895	COG1174	glycine betaine transport
HUT09_RS14900	COG1125	glycine betaine transport
HUT09_RS14900	COG0517	IMP dehydrogenase activity
HUT09_RS14910	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HUT09_RS14910	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
HUT09_RS14925	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HUT09_RS14940	COG0302	gtp cyclohydrolase
HUT09_RS14955	COG0037	tRNA processing
HUT09_RS14965	COG2027	D-alanyl-D-alanine carboxypeptidase
HUT09_RS14970	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HUT09_RS14980	COG0586	Pfam SNARE associated Golgi protein
HUT09_RS14985	COG0393	Putative heavy-metal-binding
HUT09_RS14995	COG0655	NAD(P)H dehydrogenase (quinone) activity
HUT09_RS15000	COG0076	glutamate decarboxylase activity
HUT09_RS15020	COG1012	belongs to the aldehyde dehydrogenase family
HUT09_RS15060	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HUT09_RS15060	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HUT09_RS15090	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
HUT09_RS15115	COG0726	polysaccharide deacetylase
HUT09_RS15135	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HUT09_RS15140	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HUT09_RS15175	COG3629	intracellular signal transduction
HUT09_RS15175	COG3903	Transcriptional regulator
HUT09_RS15190	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HUT09_RS15195	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HUT09_RS15200	COG1754	DNA topoisomerase type I activity
HUT09_RS15200	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HUT09_RS15210	COG2890	protein-(glutamine-N5) methyltransferase activity
HUT09_RS15220	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
HUT09_RS15230	COG1366	Belongs to the anti-sigma-factor antagonist family
HUT09_RS15235	COG1205	dead DEAH box helicase
HUT09_RS15235	COG1111	helicase
HUT09_RS15370	COG0288	reversible hydration of carbon dioxide
HUT09_RS15375	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HUT09_RS15380	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HUT09_RS15390	COG2267	carboxylic ester hydrolase activity
HUT09_RS15415	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUT09_RS15440	COG0003	Pfam Anion-transporting ATPase
HUT09_RS15450	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HUT09_RS15455	COG1610	YqeY-like protein
HUT09_RS15460	COG1408	metallophosphoesterase
HUT09_RS15480	COG2755	lipolytic protein G-D-S-L family
HUT09_RS15490	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HUT09_RS15510	COG1595	DNA-templated transcription, initiation
HUT09_RS15540	COG0702	epimerase
HUT09_RS15550	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HUT09_RS15555	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HUT09_RS15570	COG1802	Transcriptional regulator
HUT09_RS15575	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HUT09_RS15580	COG0693	protein deglycase activity
HUT09_RS15590	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HUT09_RS15590	COG0515	serine threonine protein kinase
HUT09_RS15595	COG0738	Major facilitator superfamily
HUT09_RS15605	COG3226	Transcriptional regulator
HUT09_RS15655	COG0592	DNA-directed DNA polymerase activity
HUT09_RS15680	COG0142	geranyltranstransferase activity
HUT09_RS15690	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HUT09_RS15695	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HUT09_RS15720	COG2197	response regulator
HUT09_RS15730	COG0702	epimerase
HUT09_RS15740	COG3844	kynureninase activity
HUT09_RS15755	COG0477	Major facilitator Superfamily
HUT09_RS15765	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HUT09_RS15770	COG0191	fructose-bisphosphate aldolase activity
HUT09_RS15775	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HUT09_RS15790	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HUT09_RS15815	COG0542	response to heat
HUT09_RS15840	COG0789	Transcriptional regulator
HUT09_RS15845	COG0484	heat shock protein binding
HUT09_RS15850	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HUT09_RS15855	COG0443	Heat shock 70 kDa protein
HUT09_RS15860	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HUT09_RS15865	COG0247	lactate metabolic process
HUT09_RS15865	COG2181	nitrate reductase activity
HUT09_RS15885	COG0717	Belongs to the dCTP deaminase family
HUT09_RS15930	COG1940	carbohydrate kinase activity
HUT09_RS15945	COG1028	Short-chain dehydrogenase reductase Sdr
HUT09_RS15950	COG1063	alcohol dehydrogenase
HUT09_RS15955	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HUT09_RS15960	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HUT09_RS15980	COG2205	protein histidine kinase activity
HUT09_RS15985	COG0745	RESPONSE REGULATOR receiver
HUT09_RS16000	COG1376	ErfK ybiS ycfS ynhG family protein
HUT09_RS16005	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HUT09_RS16030	COG2130	NADP-dependent
HUT09_RS16050	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HUT09_RS16070	COG1028	Short-chain dehydrogenase reductase Sdr
HUT09_RS16085	COG0367	asparagine synthase
HUT09_RS16100	COG1902	pentaerythritol trinitrate reductase activity
HUT09_RS16125	COG1686	Belongs to the peptidase S11 family
HUT09_RS16130	COG2205	protein histidine kinase activity
HUT09_RS16135	COG0745	RESPONSE REGULATOR receiver
HUT09_RS16165	COG0745	RESPONSE REGULATOR receiver
HUT09_RS16175	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HUT09_RS16185	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HUT09_RS16190	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HUT09_RS16200	COG0519	Catalyzes the synthesis of GMP from XMP
HUT09_RS16200	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HUT09_RS16210	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HUT09_RS16225	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT09_RS16230	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT09_RS16240	COG1695	Transcriptional regulator
HUT09_RS16250	COG0667	Aldo Keto reductase
HUT09_RS16260	COG1609	Transcriptional regulator
HUT09_RS16265	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HUT09_RS16290	COG2124	cytochrome p450
HUT09_RS16310	COG3585	molybdate ion transport
HUT09_RS16335	COG0531	amino acid
HUT09_RS16345	COG0475	glutathione-regulated potassium exporter activity
HUT09_RS16355	COG2409	Drug exporters of the RND superfamily
HUT09_RS16360	COG3594	Acyltransferase
HUT09_RS16375	COG0513	Belongs to the DEAD box helicase family
HUT09_RS16380	COG1278	Cold shock
HUT09_RS16420	COG5002	protein histidine kinase activity
HUT09_RS16425	COG0745	RESPONSE REGULATOR receiver
HUT09_RS16460	COG0454	-acetyltransferase
HUT09_RS16485	COG2268	Band 7 protein
HUT09_RS16525	COG0490	domain, Protein
HUT09_RS16530	COG0475	glutathione-regulated potassium exporter activity
HUT09_RS16555	COG2255	four-way junction helicase activity
HUT09_RS16565	COG0180	Tryptophanyl-tRNA synthetase
HUT09_RS16575	COG2015	COG2015, Alkyl sulfatase and related hydrolases
HUT09_RS16580	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT09_RS16610	COG0431	NADPH-dependent FMN reductase
HUT09_RS16640	COG2205	protein histidine kinase activity
HUT09_RS16645	COG0745	RESPONSE REGULATOR receiver
HUT09_RS16650	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HUT09_RS16660	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HUT09_RS16675	COG1741	Belongs to the pirin family
HUT09_RS16685	COG1960	acyl-CoA dehydrogenase activity
HUT09_RS16695	COG1362	aminopeptidase activity
HUT09_RS16720	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HUT09_RS16735	COG1802	Transcriptional regulator
HUT09_RS16755	COG0508	dehydrogenase complex catalyzes the overall conversion of
HUT09_RS16760	COG0022	dehydrogenase e1 component
HUT09_RS16785	COG0515	serine threonine protein kinase
HUT09_RS16790	COG0515	serine threonine protein kinase
HUT09_RS16805	COG1136	(ABC) transporter
HUT09_RS16805	COG4591	ABC-type transport system involved in lipoprotein release permease component
HUT09_RS16820	COG0604	alcohol dehydrogenase
HUT09_RS16820	COG1028	Short-chain dehydrogenase reductase Sdr
HUT09_RS16820	COG3321	synthase
HUT09_RS16835	COG0746	molybdenum cofactor guanylyltransferase activity
HUT09_RS16855	COG1522	sequence-specific DNA binding
HUT09_RS16860	COG1309	transcriptional regulator
HUT09_RS16885	COG3396	Phenylacetate-CoA oxygenase
HUT09_RS16890	COG3460	Phenylacetate-CoA oxygenase
HUT09_RS16895	COG3396	Phenylacetate-CoA oxygenase
HUT09_RS16900	COG2151	metal-sulfur cluster biosynthetic enzyme
HUT09_RS16905	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HUT09_RS16915	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HUT09_RS16930	COG1733	regulation of RNA biosynthetic process
HUT09_RS16935	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HUT09_RS16950	COG1716	ATPase activity
HUT09_RS16955	COG1716	ATPase activity
HUT09_RS16970	COG0768	penicillin binding
HUT09_RS16975	COG0515	serine threonine protein kinase
HUT09_RS16980	COG3764	Sortase (surface protein transpeptidase)
HUT09_RS16985	COG3764	Sortase (surface protein transpeptidase)
HUT09_RS17000	COG3764	Sortase (surface protein transpeptidase)
HUT09_RS17015	COG0705	Rhomboid family
HUT09_RS17060	COG0515	serine threonine protein kinase
HUT09_RS17090	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HUT09_RS17100	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
HUT09_RS17105	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HUT09_RS17110	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
HUT09_RS17115	COG0592	DNA-directed DNA polymerase activity
HUT09_RS17125	COG0230	Belongs to the bacterial ribosomal protein bL34 family
HUT09_RS17130	COG0594	ribonuclease P activity
HUT09_RS17135	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
HUT09_RS17140	COG0706	membrane insertase activity
HUT09_RS17150	COG0357	Ribosomal RNA small subunit methyltransferase G
HUT09_RS17155	COG1192	Involved in chromosome partitioning
HUT09_RS17170	COG3118	belongs to the thioredoxin family
HUT09_RS17175	COG0492	ferredoxin-NADP+ reductase activity
HUT09_RS17185	COG1595	DNA-templated transcription, initiation
HUT09_RS17190	COG0515	serine threonine protein kinase
HUT09_RS17190	COG2815	serine threonine protein kinase
HUT09_RS17205	COG0617	tRNA 3'-terminal CCA addition
HUT09_RS17225	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HUT09_RS17250	COG0360	Binds together with S18 to 16S ribosomal RNA
HUT09_RS17255	COG0629	single-stranded DNA binding
HUT09_RS17260	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HUT09_RS17265	COG0359	binds to the 23S rRNA
HUT09_RS17270	COG0534	Mate efflux family protein
HUT09_RS17275	COG0305	Participates in initiation and elongation during chromosome replication
HUT09_RS17290	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HUT09_RS17295	COG0456	acetyltransferase
HUT09_RS17305	COG2814	Major facilitator Superfamily
HUT09_RS17325	COG0626	cystathionine gamma-synthase activity
HUT09_RS17330	COG1950	PFAM Membrane protein of
HUT09_RS17335	COG0662	Cupin 2, conserved barrel domain protein
HUT09_RS17360	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HUT09_RS17370	COG3152	Membrane
HUT09_RS17380	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HUT09_RS17385	COG1609	Transcriptional regulator
HUT09_RS17390	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HUT09_RS17395	COG1271	oxidase subunit
HUT09_RS17400	COG1294	oxidase, subunit
HUT09_RS17405	COG4988	ABC transporter
HUT09_RS17415	COG0561	phosphatase activity
HUT09_RS17425	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
HUT09_RS17430	COG0789	Transcriptional regulator
HUT09_RS17445	COG1131	(ABC) transporter
HUT09_RS17470	COG0561	phosphatase activity
HUT09_RS17475	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HUT09_RS17485	COG2837	iron assimilation
HUT09_RS17490	COG2372	response to copper ion
HUT09_RS17500	COG1999	signal sequence binding
HUT09_RS17520	COG0006	proline dipeptidase activity
HUT09_RS17540	COG0653	protein targeting
HUT09_RS17555	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HUT09_RS17580	COG1960	acyl-CoA dehydrogenase activity
HUT09_RS17605	COG1595	DNA-templated transcription, initiation
HUT09_RS17610	COG0318	PFAM AMP-dependent synthetase and ligase
HUT09_RS17640	COG1595	DNA-templated transcription, initiation
HUT09_RS17660	COG0745	RESPONSE REGULATOR receiver
HUT09_RS17665	COG2205	protein histidine kinase activity
HUT09_RS17675	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HUT09_RS17690	COG0477	Major facilitator Superfamily
HUT09_RS17705	COG3467	pyridoxamine 5'-phosphate
HUT09_RS17710	COG2353	YceI-like domain
HUT09_RS17735	COG1191	sigma factor activity
HUT09_RS17740	COG1191	sigma factor activity
HUT09_RS17775	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HUT09_RS17805	COG4941	Belongs to the sigma-70 factor family
HUT09_RS17865	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HUT09_RS17870	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
HUT09_RS17970	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HUT09_RS17975	COG2188	Transcriptional regulator
HUT09_RS18055	COG0151	Belongs to the GarS family
HUT09_RS18070	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
HUT09_RS18080	COG2197	response regulator
HUT09_RS18115	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HUT09_RS18120	COG0047	phosphoribosylformylglycinamidine synthase activity
HUT09_RS18125	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HUT09_RS18135	COG1196	nuclear chromosome segregation
HUT09_RS18135	COG0741	lytic transglycosylase activity
HUT09_RS18135	COG0739	heme binding
HUT09_RS18155	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
HUT09_RS18190	COG1643	Atp-dependent helicase
HUT09_RS18200	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HUT09_RS18200	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HUT09_RS18205	COG0785	Cytochrome C biogenesis protein
HUT09_RS18235	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HUT09_RS18240	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HUT09_RS18250	COG0513	Belongs to the DEAD box helicase family
HUT09_RS18260	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HUT09_RS18270	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HUT09_RS18285	COG0789	Transcriptional regulator
HUT09_RS18295	COG0741	lytic transglycosylase activity
HUT09_RS18295	COG0739	heme binding
HUT09_RS18295	COG1196	nuclear chromosome segregation
HUT09_RS18300	COG0667	Aldo Keto reductase
HUT09_RS18310	COG0220	tRNA (guanine-N7-)-methyltransferase activity
HUT09_RS18315	COG0579	oxidoreductase
HUT09_RS18340	COG1252	NADH dehydrogenase
HUT09_RS18355	COG1846	Transcriptional regulator
HUT09_RS18375	COG2197	response regulator
HUT09_RS18380	COG4585	Histidine kinase
HUT09_RS18390	COG1131	(ABC) transporter
HUT09_RS18455	COG1196	nuclear chromosome segregation
HUT09_RS18455	COG0741	lytic transglycosylase activity
HUT09_RS18455	COG0739	heme binding
HUT09_RS18460	COG0671	phosphoesterase, PA-phosphatase related
HUT09_RS18475	COG1937	Protein conserved in bacteria
HUT09_RS18485	COG0306	phosphate transporter
HUT09_RS18505	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HUT09_RS18510	COG0406	alpha-ribazole phosphatase activity
HUT09_RS18510	COG0494	nUDIX hydrolase
HUT09_RS18530	COG1116	anion transmembrane transporter activity
HUT09_RS18535	COG1725	Transcriptional regulator
HUT09_RS18545	COG0456	acetyltransferase
HUT09_RS18555	COG0737	Belongs to the 5'-nucleotidase family
HUT09_RS18570	COG0154	amidase activity
HUT09_RS18635	COG0789	Transcriptional regulator
HUT09_RS18650	COG0823	Involved in the tonB-independent uptake of proteins
HUT09_RS18670	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HUT09_RS18680	COG1609	Transcriptional regulator
HUT09_RS18685	COG0745	RESPONSE REGULATOR receiver
HUT09_RS18710	COG2897	thiosulfate sulfurtransferase activity
HUT09_RS18745	COG3485	protocatechuate 3,4-dioxygenase
HUT09_RS18750	COG0735	belongs to the Fur family
HUT09_RS18760	COG1490	D-aminoacyl-tRNA deacylase activity
HUT09_RS18775	COG4552	Acetyltransferase involved in intracellular survival and related
HUT09_RS18825	COG0475	glutathione-regulated potassium exporter activity
HUT09_RS18840	COG1846	Transcriptional regulator
HUT09_RS18855	COG4770	biotin carboxylase activity
HUT09_RS18880	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HUT09_RS18910	COG0736	holo-[acyl-carrier-protein] synthase activity
HUT09_RS18915	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HUT09_RS18940	COG2318	DinB family
HUT09_RS18950	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT09_RS18960	COG1733	regulation of RNA biosynthetic process
HUT09_RS19010	COG0438	transferase activity, transferring glycosyl groups
HUT09_RS19115	COG1609	Transcriptional regulator
HUT09_RS19160	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
HUT09_RS19170	COG0588	phosphoglycerate mutase activity
HUT09_RS19190	COG5002	protein histidine kinase activity
HUT09_RS19205	COG1329	Transcriptional regulator
HUT09_RS19210	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
HUT09_RS19215	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
HUT09_RS19225	COG0215	cysteine-tRNA ligase activity
HUT09_RS19230	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HUT09_RS19240	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HUT09_RS19250	COG3842	ATPase activity
HUT09_RS19265	COG3631	Ketosteroid isomerase-related protein
HUT09_RS19270	COG0702	epimerase
HUT09_RS19290	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HUT09_RS19310	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HUT09_RS19330	COG2197	response regulator
HUT09_RS19335	COG4585	Histidine kinase
HUT09_RS19345	COG0666	response to abiotic stimulus
HUT09_RS19370	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HUT09_RS19395	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HUT09_RS19420	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
HUT09_RS19425	COG0463	Glycosyl transferase, family 2
HUT09_RS19475	COG1132	(ABC) transporter
HUT09_RS19485	COG1595	DNA-templated transcription, initiation
HUT09_RS19510	COG0395	ABC-type sugar transport system, permease component
HUT09_RS19515	COG1175	transmembrane transport
HUT09_RS19560	COG4251	negative regulation of phosphorylation
HUT09_RS19580	COG0477	Major facilitator Superfamily
HUT09_RS19590	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HUT09_RS19590	COG1263	PTS System
HUT09_RS19595	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HUT09_RS19600	COG1737	Transcriptional regulator
HUT09_RS19640	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
HUT09_RS19660	COG3142	Participates in the control of copper homeostasis
HUT09_RS19665	COG3973	AAA domain
HUT09_RS19675	COG1061	Type III restriction enzyme res subunit
HUT09_RS19690	COG0006	proline dipeptidase activity
HUT09_RS19695	COG4934	collagen metabolic process
HUT09_RS19740	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HUT09_RS19745	COG1120	ATPase activity
HUT09_RS19750	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT09_RS19755	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT09_RS19780	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
HUT09_RS19785	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HUT09_RS19795	COG2814	Major facilitator Superfamily
HUT09_RS19825	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HUT09_RS19835	COG2252	PERMEase
HUT09_RS19845	COG1846	Transcriptional regulator
HUT09_RS19855	COG0667	Aldo Keto reductase
HUT09_RS19865	COG2267	carboxylic ester hydrolase activity
HUT09_RS19875	COG0515	serine threonine protein kinase
HUT09_RS19885	COG1028	Short-chain dehydrogenase reductase Sdr
HUT09_RS19890	COG0583	DNA-binding transcription factor activity
HUT09_RS19910	COG1595	DNA-templated transcription, initiation
HUT09_RS19970	COG1309	transcriptional regulator
HUT09_RS19980	COG0697	spore germination
HUT09_RS19995	COG2130	NADP-dependent
HUT09_RS20045	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HUT09_RS20065	COG1335	isochorismatase
HUT09_RS20095	COG2318	DinB family
HUT09_RS20105	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HUT09_RS20135	COG2205	protein histidine kinase activity
HUT09_RS20140	COG0277	FAD linked oxidase domain protein
HUT09_RS20140	COG0247	lactate metabolic process
HUT09_RS20145	COG3896	Chloramphenicol phosphotransferase-like protein
HUT09_RS20150	COG0583	DNA-binding transcription factor activity
HUT09_RS20155	COG5006	permease, DMT superfamily
HUT09_RS20160	COG2402	Toxic component of a toxin-antitoxin (TA) module. An RNase
HUT09_RS20170	COG0494	nUDIX hydrolase
HUT09_RS20185	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HUT09_RS20200	COG0318	PFAM AMP-dependent synthetase and ligase
HUT09_RS20205	COG1024	Enoyl-CoA hydratase
HUT09_RS20235	COG0456	acetyltransferase
HUT09_RS20245	COG2124	cytochrome p450
HUT09_RS20270	COG0259	pyridoxamine-phosphate oxidase activity
HUT09_RS20280	COG0577	efflux transmembrane transporter activity
HUT09_RS20280	COG1136	(ABC) transporter
HUT09_RS20285	COG0577	efflux transmembrane transporter activity
HUT09_RS20285	COG1136	(ABC) transporter
HUT09_RS20300	COG0745	RESPONSE REGULATOR receiver
HUT09_RS20305	COG2205	protein histidine kinase activity
HUT09_RS20310	COG4821	SIS domain
HUT09_RS20320	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HUT09_RS20335	COG1131	(ABC) transporter
HUT09_RS20390	COG0318	PFAM AMP-dependent synthetase and ligase
HUT09_RS20400	COG1960	acyl-CoA dehydrogenase activity
HUT09_RS20405	COG1960	acyl-CoA dehydrogenase activity
HUT09_RS20420	COG1028	Short-chain dehydrogenase reductase Sdr
HUT09_RS20425	COG1960	acyl-CoA dehydrogenase activity
HUT09_RS20475	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HUT09_RS20485	COG0346	lactoylglutathione lyase activity
HUT09_RS20505	COG1024	Enoyl-CoA hydratase
HUT09_RS20530	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HUT09_RS20540	COG0702	epimerase
HUT09_RS20545	COG2234	aminopeptidase activity
HUT09_RS20555	COG2072	flavoprotein involved in K transport
HUT09_RS20560	COG4592	Periplasmic binding protein
HUT09_RS20565	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT09_RS20570	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT09_RS20590	COG0501	Belongs to the peptidase M48B family
HUT09_RS20595	COG0259	pyridoxamine-phosphate oxidase activity
HUT09_RS20605	COG1960	acyl-CoA dehydrogenase activity
HUT09_RS20615	COG1309	transcriptional regulator
HUT09_RS20640	COG1024	Enoyl-CoA hydratase
HUT09_RS20680	COG1278	Cold shock
HUT09_RS20685	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
HUT09_RS20695	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
HUT09_RS20720	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HUT09_RS20725	COG4521	taurine ABC transporter
HUT09_RS20735	COG2175	clavaminate synthase activity
HUT09_RS20740	COG2226	methyltransferase
HUT09_RS20785	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUT09_RS20790	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUT09_RS20795	COG0649	NAD binding
HUT09_RS20805	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HUT09_RS20810	COG1034	ATP synthesis coupled electron transport
HUT09_RS20815	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
HUT09_RS20820	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUT09_RS20825	COG0839	Belongs to the complex I subunit 6 family
HUT09_RS20830	COG0713	ATP synthesis coupled electron transport
HUT09_RS20835	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HUT09_RS20845	COG1007	ATP synthesis coupled electron transport
HUT09_RS20850	COG0514	ATP-dependent DNA helicase (RecQ)
HUT09_RS20860	COG0179	Fumarylacetoacetate (FAA) hydrolase
HUT09_RS20870	COG3104	oligopeptide transport
HUT09_RS20875	COG0142	geranyltranstransferase activity
HUT09_RS20885	COG1131	(ABC) transporter
HUT09_RS20915	COG0561	phosphatase activity
HUT09_RS20955	COG0346	lactoylglutathione lyase activity
HUT09_RS20985	COG0702	epimerase
HUT09_RS20990	COG1733	regulation of RNA biosynthetic process
HUT09_RS20995	COG1013	pyruvate-flavodoxin oxidoreductase activity
HUT09_RS21000	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HUT09_RS21000	COG0674	pyruvate-flavodoxin oxidoreductase activity
HUT09_RS21020	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUT09_RS21025	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUT09_RS21030	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUT09_RS21035	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
HUT09_RS21040	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUT09_RS21045	COG0839	Belongs to the complex I subunit 6 family
HUT09_RS21050	COG0713	ATP synthesis coupled electron transport
HUT09_RS21065	COG1007	ATP synthesis coupled electron transport
HUT09_RS21070	COG1970	mechanosensitive ion channel activity
HUT09_RS21075	COG0501	Belongs to the peptidase M48B family
HUT09_RS21080	COG3304	Inner membrane component domain
HUT09_RS21095	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HUT09_RS21100	COG1666	GTP binding
HUT09_RS21130	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HUT09_RS21135	COG2030	dehydratase
HUT09_RS21145	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HUT09_RS21160	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HUT09_RS21165	COG0436	Aminotransferase
HUT09_RS21185	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HUT09_RS21190	COG0081	regulation of translation
HUT09_RS21200	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HUT09_RS21205	COG0222	ribosome binding
HUT09_RS21210	COG0085	RNA polymerase activity
HUT09_RS21215	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HUT09_RS21320	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HUT09_RS21325	COG0049	tRNA binding
HUT09_RS21330	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HUT09_RS21355	COG0051	transcription antitermination factor activity, RNA binding
HUT09_RS21360	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HUT09_RS21365	COG0088	Forms part of the polypeptide exit tunnel
HUT09_RS21370	COG0089	rRNA binding
HUT09_RS21375	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HUT09_RS21380	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HUT09_RS21385	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HUT09_RS21390	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HUT09_RS21395	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HUT09_RS21400	COG0255	Belongs to the universal ribosomal protein uL29 family
HUT09_RS21405	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HUT09_RS21410	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HUT09_RS21415	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HUT09_RS21420	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HUT09_RS21425	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HUT09_RS21430	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HUT09_RS21435	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HUT09_RS21440	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HUT09_RS21445	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HUT09_RS21450	COG1841	ribosomal large subunit assembly
HUT09_RS21455	COG0200	Binds to the 23S rRNA
HUT09_RS21465	COG0563	adenylate kinase activity
HUT09_RS21475	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HUT09_RS21480	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HUT09_RS21485	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HUT09_RS21490	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HUT09_RS21495	COG0202	RNA polymerase activity
HUT09_RS21500	COG0203	ribosomal protein L17
HUT09_RS21505	COG0101	tRNA pseudouridine synthase activity
HUT09_RS21520	COG0488	(ABC) transporter
HUT09_RS21525	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HUT09_RS21530	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
HUT09_RS21535	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HUT09_RS21545	COG1072	(Pantothenic acid kinase))
HUT09_RS21565	COG0747	negative chemotaxis
HUT09_RS21575	COG3795	YCII-related domain
HUT09_RS21580	COG4941	Belongs to the sigma-70 factor family
HUT09_RS21600	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HUT09_RS21605	COG0736	holo-[acyl-carrier-protein] synthase activity
HUT09_RS21615	COG3189	MarR family transcriptional regulator
HUT09_RS21620	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HUT09_RS21630	COG0802	atpase or kinase
HUT09_RS21655	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HUT09_RS21695	COG0726	polysaccharide deacetylase
HUT09_RS21705	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HUT09_RS21720	COG0395	ABC-type sugar transport system, permease component
HUT09_RS21725	COG1175	transmembrane transport
HUT09_RS21740	COG4221	oxidoreductase activity
HUT09_RS21750	COG0583	DNA-binding transcription factor activity
HUT09_RS21765	COG1595	DNA-templated transcription, initiation
HUT09_RS21775	COG0516	GMP reductase activity
HUT09_RS21805	COG0515	serine threonine protein kinase
HUT09_RS21810	COG1012	belongs to the aldehyde dehydrogenase family
HUT09_RS21830	COG0519	Catalyzes the synthesis of GMP from XMP
HUT09_RS21830	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HUT09_RS21860	COG2197	response regulator
HUT09_RS21870	COG0791	NLP P60 protein
HUT09_RS21895	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HUT09_RS21910	COG0714	Associated with various cellular activities
HUT09_RS21915	COG2425	protein containing a von Willebrand factor type A (vWA) domain
HUT09_RS21920	COG3552	Protein containing von Willebrand factor type A (VWA) domain
HUT09_RS21925	COG0045	succinate-CoA ligase (ADP-forming) activity
HUT09_RS21955	COG0138	bifunctional purine biosynthesis protein purh
HUT09_RS21970	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HUT09_RS21985	COG0039	L-malate dehydrogenase activity
HUT09_RS22005	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HUT09_RS22010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUT09_RS22025	COG0754	glutathionylspermidine amidase activity
HUT09_RS22030	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HUT09_RS22035	COG0180	Tryptophanyl-tRNA synthetase
HUT09_RS22055	COG1295	ribonuclease BN
HUT09_RS22060	COG1686	Belongs to the peptidase S11 family
HUT09_RS22065	COG1408	metallophosphoesterase
HUT09_RS22075	COG1309	transcriptional regulator
HUT09_RS22100	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HUT09_RS22105	COG1053	succinate dehydrogenase
HUT09_RS22115	COG2009	succinate dehydrogenase
HUT09_RS22140	COG1231	oxidoreductase activity
HUT09_RS22225	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HUT09_RS22240	COG1595	DNA-templated transcription, initiation
HUT09_RS22285	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
HUT09_RS22295	COG1216	Glycosyl transferase, family 2
HUT09_RS22305	COG1083	cytidylyl-transferase
HUT09_RS22310	COG2089	acid synthase
HUT09_RS22320	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
HUT09_RS22320	COG1473	amidohydrolase
HUT09_RS22325	COG1744	ABC transporter substrate-binding protein PnrA-like
HUT09_RS22330	COG3845	ABC transporter
HUT09_RS22335	COG4603	Belongs to the binding-protein-dependent transport system permease family
HUT09_RS22340	COG1079	Belongs to the binding-protein-dependent transport system permease family
HUT09_RS22360	COG1404	Belongs to the peptidase S8 family
HUT09_RS22380	COG2814	Major facilitator Superfamily
HUT09_RS22385	COG0583	DNA-binding transcription factor activity
HUT09_RS22395	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HUT09_RS22420	COG2205	protein histidine kinase activity
HUT09_RS22425	COG0745	RESPONSE REGULATOR receiver
HUT09_RS22430	COG1595	DNA-templated transcription, initiation
HUT09_RS22460	COG1012	belongs to the aldehyde dehydrogenase family
HUT09_RS22465	COG1012	belongs to the aldehyde dehydrogenase family
HUT09_RS22480	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HUT09_RS22510	COG4770	biotin carboxylase activity
HUT09_RS22520	COG0424	maF-like protein
HUT09_RS22530	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HUT09_RS22545	COG1024	Enoyl-CoA hydratase
HUT09_RS22570	COG1376	ErfK ybiS ycfS ynhG family protein
HUT09_RS22590	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HUT09_RS22615	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HUT09_RS22640	COG1595	DNA-templated transcription, initiation
HUT09_RS22650	COG5002	protein histidine kinase activity
HUT09_RS22650	COG0784	Response regulator, receiver
HUT09_RS22650	COG2198	Histidine kinase
HUT09_RS22660	COG2172	sigma factor antagonist activity
HUT09_RS22665	COG1366	Belongs to the anti-sigma-factor antagonist family
HUT09_RS22670	COG1366	Belongs to the anti-sigma-factor antagonist family
HUT09_RS22675	COG2255	four-way junction helicase activity
HUT09_RS22680	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HUT09_RS22695	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HUT09_RS22705	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HUT09_RS22725	COG1331	Highly conserved protein containing a thioredoxin domain
HUT09_RS22735	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
HUT09_RS22800	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
HUT09_RS22815	COG1414	Transcriptional regulator
HUT09_RS22820	COG0251	oxidation-reduction process
HUT09_RS22825	COG2610	gluconate transmembrane transporter activity
HUT09_RS22860	COG2894	cell division
HUT09_RS22890	COG3920	Histidine kinase
HUT09_RS22895	COG2197	response regulator
HUT09_RS22915	COG2885	chlorophyll binding
HUT09_RS22975	COG0667	Aldo Keto reductase
HUT09_RS22980	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HUT09_RS22985	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
HUT09_RS23000	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HUT09_RS23005	COG0450	alkyl hydroperoxide reductase
HUT09_RS23020	COG1136	(ABC) transporter
HUT09_RS23040	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HUT09_RS23040	COG4499	WXG100 protein secretion system (Wss), protein YukC
HUT09_RS23055	COG0114	fumarate hydratase activity
HUT09_RS23065	COG1362	aminopeptidase activity
HUT09_RS23070	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HUT09_RS23070	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HUT09_RS23095	COG0778	Nitroreductase
HUT09_RS23100	COG1722	exodeoxyribonuclease VII activity
HUT09_RS23105	COG1570	exodeoxyribonuclease VII activity
HUT09_RS23115	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HUT09_RS23130	COG0012	GTP binding
HUT09_RS23190	COG0789	Transcriptional regulator
HUT09_RS23195	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HUT09_RS23235	COG1842	Phage shock protein A
HUT09_RS23245	COG0463	Glycosyl transferase, family 2
HUT09_RS23255	COG4941	Belongs to the sigma-70 factor family
HUT09_RS23260	COG3795	YCII-related domain
HUT09_RS23350	COG0148	phosphopyruvate hydratase activity
HUT09_RS23370	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HUT09_RS23400	COG0395	ABC-type sugar transport system, permease component
HUT09_RS23405	COG1175	transmembrane transport
HUT09_RS23420	COG2050	protein possibly involved in aromatic compounds catabolism
HUT09_RS23435	COG1217	gtp-binding protein TYPA
HUT09_RS23445	COG0601	transmembrane transport
HUT09_RS23450	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HUT09_RS23460	COG4608	Belongs to the ABC transporter superfamily
HUT09_RS23465	COG4166	transmembrane transport
HUT09_RS23470	COG0601	transmembrane transport
HUT09_RS23475	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HUT09_RS23485	COG4608	Belongs to the ABC transporter superfamily
HUT09_RS23500	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HUT09_RS23515	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HUT09_RS23530	COG0110	maltose O-acetyltransferase activity
HUT09_RS23545	COG0515	serine threonine protein kinase
HUT09_RS23555	COG1132	(ABC) transporter
HUT09_RS23560	COG1132	(ABC) transporter
HUT09_RS23565	COG2197	response regulator
HUT09_RS23570	COG2912	Transglutaminase-like superfamily
HUT09_RS23600	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HUT09_RS23605	COG1611	Belongs to the LOG family
HUT09_RS23610	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HUT09_RS23620	COG0519	Catalyzes the synthesis of GMP from XMP
HUT09_RS23625	COG1024	Enoyl-CoA hydratase
HUT09_RS23640	COG1595	DNA-templated transcription, initiation
HUT09_RS23650	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HUT09_RS23655	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HUT09_RS23690	COG0598	Magnesium transport protein CorA
HUT09_RS23700	COG2814	Major facilitator Superfamily
HUT09_RS23710	COG0613	PHP domain protein
HUT09_RS23715	COG2095	MarC family integral membrane protein
HUT09_RS23725	COG1432	Conserved Protein
HUT09_RS23735	COG0513	Belongs to the DEAD box helicase family
HUT09_RS23775	COG0747	negative chemotaxis
HUT09_RS23780	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HUT09_RS23785	COG0601	transmembrane transport
HUT09_RS23845	COG0210	DNA helicase
HUT09_RS23890	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HUT09_RS23945	COG3480	Lon protease (S16) C-terminal proteolytic domain
HUT09_RS23955	COG1615	UPF0182 protein
HUT09_RS23980	COG0753	catalase activity
HUT09_RS23990	COG0483	inositol monophosphate 1-phosphatase activity
HUT09_RS24005	COG2076	Multidrug Resistance protein
HUT09_RS24010	COG1162	GTPase activity
HUT09_RS24015	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
HUT09_RS24025	COG2135	peptidase activity
HUT09_RS24035	COG1595	DNA-templated transcription, initiation
HUT09_RS24040	COG5662	AntiSigma factor
HUT09_RS24060	COG0242	peptide deformylase activity
HUT09_RS24105	COG1966	Carbon starvation protein
HUT09_RS24115	COG2182	Extracellular solute-binding protein
HUT09_RS24120	COG1175	transmembrane transport
HUT09_RS24125	COG0395	ABC-type sugar transport system, permease component
HUT09_RS24130	COG1472	Belongs to the glycosyl hydrolase 3 family
HUT09_RS24135	COG0363	glucosamine-6-phosphate deaminase activity
HUT09_RS24140	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HUT09_RS24155	COG1597	lipid kinase activity
HUT09_RS24170	COG2172	sigma factor antagonist activity
HUT09_RS24195	COG1959	2 iron, 2 sulfur cluster binding
HUT09_RS24200	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HUT09_RS24205	COG0142	geranyltranstransferase activity
HUT09_RS24225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUT09_RS24260	COG2197	response regulator
HUT09_RS24265	COG4585	Histidine kinase
HUT09_RS24300	COG4106	trans-aconitate 2-methyltransferase activity
HUT09_RS24305	COG1595	DNA-templated transcription, initiation
HUT09_RS24315	COG1126	abc transporter atp-binding protein
HUT09_RS24320	COG0765	amino acid transport
HUT09_RS24330	COG0281	malic enzyme
HUT09_RS24335	COG0604	alcohol dehydrogenase
HUT09_RS24340	COG1874	Beta-galactosidase
HUT09_RS24355	COG0542	response to heat
HUT09_RS24380	COG0508	dehydrogenase complex catalyzes the overall conversion of
HUT09_RS24380	COG0567	Dehydrogenase, E1 component
HUT09_RS24385	COG2205	protein histidine kinase activity
HUT09_RS24390	COG0745	RESPONSE REGULATOR receiver
HUT09_RS24410	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HUT09_RS24415	COG0726	polysaccharide deacetylase
HUT09_RS24420	COG1846	Transcriptional regulator
HUT09_RS24430	COG5002	protein histidine kinase activity
HUT09_RS24455	COG3883	PFAM NLP P60 protein
HUT09_RS24455	COG0791	NLP P60 protein
HUT09_RS24470	COG1309	transcriptional regulator
HUT09_RS24505	COG0768	penicillin binding
HUT09_RS24520	COG2205	protein histidine kinase activity
HUT09_RS24540	COG1793	dna ligase
HUT09_RS24540	COG3285	dna ligase
HUT09_RS24545	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HUT09_RS24560	COG3629	intracellular signal transduction
HUT09_RS24560	COG3903	Transcriptional regulator
HUT09_RS24570	COG3629	intracellular signal transduction
HUT09_RS24570	COG3903	Transcriptional regulator
HUT09_RS24590	COG0018	arginyl-trna synthetase
HUT09_RS24595	COG0019	diaminopimelate decarboxylase activity
HUT09_RS24600	COG0460	homoserine dehydrogenase
HUT09_RS24605	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HUT09_RS24610	COG0083	homoserine kinase activity
HUT09_RS24620	COG1316	TRANSCRIPTIONal
HUT09_RS24625	COG0254	rRNA binding
HUT09_RS24630	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HUT09_RS24635	COG2890	protein-(glutamine-N5) methyltransferase activity
HUT09_RS24645	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HUT09_RS24660	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HUT09_RS24680	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HUT09_RS24685	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HUT09_RS24690	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HUT09_RS24695	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HUT09_RS24700	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HUT09_RS24705	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HUT09_RS24710	COG0355	proton-transporting ATP synthase activity, rotational mechanism
HUT09_RS24725	COG2197	response regulator
HUT09_RS24745	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUT09_RS24760	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
HUT09_RS24815	COG0183	Belongs to the thiolase family
HUT09_RS24840	COG0745	RESPONSE REGULATOR receiver
HUT09_RS24845	COG5002	protein histidine kinase activity
HUT09_RS24915	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HUT09_RS24915	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HUT09_RS24920	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
HUT09_RS24955	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HUT09_RS24960	COG0857	belongs to the CobB CobQ family
HUT09_RS24960	COG0280	phosphate acetyltransferase
HUT09_RS24965	COG0205	6-phosphofructokinase activity
HUT09_RS24975	COG4565	transcriptional regulatory protein
HUT09_RS24980	COG3290	protein histidine kinase activity
HUT09_RS24985	COG1301	dicarboxylic acid transport
HUT09_RS24995	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HUT09_RS25000	COG3281	Trehalose synthase
HUT09_RS25005	COG0366	Alpha amylase catalytic
HUT09_RS25010	COG0366	Alpha amylase catalytic
HUT09_RS25015	COG0058	SHG alpha-glucan phosphorylase activity
HUT09_RS25050	COG1132	(ABC) transporter
HUT09_RS25055	COG1132	(ABC) transporter
HUT09_RS25060	COG1131	(ABC) transporter
HUT09_RS25075	COG2197	response regulator
HUT09_RS25160	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HUT09_RS25165	COG0142	geranyltranstransferase activity
HUT09_RS25170	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HUT09_RS25175	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HUT09_RS25220	COG0477	Major facilitator Superfamily
HUT09_RS25230	COG1028	Short-chain dehydrogenase reductase Sdr
HUT09_RS25365	COG0823	Involved in the tonB-independent uptake of proteins
HUT09_RS25365	COG1506	peptidase
HUT09_RS25400	COG1028	Short-chain dehydrogenase reductase Sdr
HUT09_RS25415	COG1929	Belongs to the glycerate kinase type-1 family
HUT09_RS25425	COG0745	RESPONSE REGULATOR receiver
HUT09_RS25430	COG2205	protein histidine kinase activity
HUT09_RS25470	COG1760	l-serine dehydratase
HUT09_RS25475	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HUT09_RS25480	COG0509	glycine decarboxylation via glycine cleavage system
HUT09_RS25485	COG0404	The glycine cleavage system catalyzes the degradation of glycine
HUT09_RS25505	COG4166	transmembrane transport
HUT09_RS25510	COG0601	transmembrane transport
HUT09_RS25515	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HUT09_RS25520	COG0444	Belongs to the ABC transporter superfamily
HUT09_RS25525	COG4608	Belongs to the ABC transporter superfamily
HUT09_RS25530	COG2860	membrane
HUT09_RS25565	COG0482	sulfurtransferase activity
HUT09_RS25585	COG4221	oxidoreductase activity
HUT09_RS25595	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HUT09_RS25605	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HUT09_RS25610	COG0154	amidase activity
HUT09_RS25620	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HUT09_RS25625	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HUT09_RS25635	COG2409	Drug exporters of the RND superfamily
HUT09_RS25655	COG2133	pyrroloquinoline quinone binding
HUT09_RS25660	COG0667	Aldo Keto reductase
HUT09_RS25680	COG0440	acetolactate synthase activity
HUT09_RS25685	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HUT09_RS25690	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HUT09_RS25710	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HUT09_RS25715	COG2508	Transcriptional regulator
HUT09_RS25720	COG0506	proline dehydrogenase activity
HUT09_RS25725	COG1012	belongs to the aldehyde dehydrogenase family
HUT09_RS25730	COG0778	Nitroreductase
HUT09_RS25730	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
HUT09_RS25745	COG2130	NADP-dependent
HUT09_RS25750	COG0583	DNA-binding transcription factor activity
HUT09_RS25755	COG0473	3-isopropylmalate dehydrogenase activity
HUT09_RS25760	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HUT09_RS25795	COG2957	Belongs to the agmatine deiminase family
HUT09_RS25805	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HUT09_RS25820	COG4608	Belongs to the ABC transporter superfamily
HUT09_RS25825	COG0601	transmembrane transport
HUT09_RS25830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HUT09_RS25835	COG0444	Belongs to the ABC transporter superfamily
HUT09_RS25845	COG1472	Belongs to the glycosyl hydrolase 3 family
HUT09_RS25865	COG3708	Transcriptional regulator
HUT09_RS25865	COG2207	Transcriptional regulator
HUT09_RS25890	COG0492	ferredoxin-NADP+ reductase activity
HUT09_RS25915	COG1733	regulation of RNA biosynthetic process
HUT09_RS25940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT09_RS25945	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT09_RS25950	COG1120	ATPase activity
HUT09_RS25955	COG4607	ABC-type enterochelin transport system periplasmic component
HUT09_RS25985	COG0366	Alpha amylase catalytic
HUT09_RS25985	COG1470	cell adhesion involved in biofilm formation
HUT09_RS25990	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HUT09_RS26010	COG2018	Roadblock/LC7 domain
HUT09_RS26030	COG2018	Roadblock/LC7 domain
HUT09_RS26035	COG5002	protein histidine kinase activity
HUT09_RS26045	COG0179	Fumarylacetoacetate (FAA) hydrolase
HUT09_RS26050	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HUT09_RS26085	COG1414	Transcriptional regulator
HUT09_RS26090	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HUT09_RS26095	COG0066	3-isopropylmalate dehydratase activity
HUT09_RS26105	COG0776	regulation of translation
HUT09_RS26115	COG1920	GTP binding
HUT09_RS26125	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
HUT09_RS26130	COG1181	Belongs to the D-alanine--D-alanine ligase family
HUT09_RS26145	COG0351	phosphomethylpyrimidine kinase
HUT09_RS26150	COG0227	Belongs to the bacterial ribosomal protein bL28 family
HUT09_RS26155	COG1461	Dihydroxyacetone kinase
HUT09_RS26160	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HUT09_RS26165	COG0742	ribosomal rna small subunit methyltransferase
HUT09_RS26170	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HUT09_RS26185	COG0333	Belongs to the bacterial ribosomal protein bL32 family
HUT09_RS26190	COG0571	ribonuclease III activity
HUT09_RS26195	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HUT09_RS26200	COG1733	regulation of RNA biosynthetic process
HUT09_RS26205	COG2340	Cysteine-rich secretory protein family
HUT09_RS26210	COG1254	Belongs to the acylphosphatase family
HUT09_RS26220	COG1196	nuclear chromosome segregation
HUT09_RS26225	COG0477	Major facilitator Superfamily
HUT09_RS26260	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
HUT09_RS26280	COG0228	four-way junction DNA binding
HUT09_RS26285	COG1837	Belongs to the UPF0109 family
HUT09_RS26290	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HUT09_RS26295	COG0336	Belongs to the RNA methyltransferase TrmD family
HUT09_RS26300	COG0335	large ribosomal subunit rRNA binding
HUT09_RS26315	COG0681	Belongs to the peptidase S26 family
HUT09_RS26320	COG0681	Belongs to the peptidase S26 family
HUT09_RS26335	COG0792	nuclease activity
HUT09_RS26350	COG1191	sigma factor activity
HUT09_RS26365	COG0052	Belongs to the universal ribosomal protein uS2 family
HUT09_RS26370	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HUT09_RS26375	COG0528	UMP kinase activity
HUT09_RS26380	COG0233	cytoplasmic translational termination
HUT09_RS26390	COG0820	rRNA (adenine-C2-)-methyltransferase activity
HUT09_RS26405	COG3842	ATPase activity
HUT09_RS26420	COG1136	(ABC) transporter
HUT09_RS26425	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HUT09_RS26435	COG1012	belongs to the aldehyde dehydrogenase family
HUT09_RS26455	COG0584	glycerophosphoryl diester phosphodiesterase
HUT09_RS26460	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HUT09_RS26480	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HUT09_RS26485	COG3842	ATPase activity
HUT09_RS26490	COG1176	ABC-type spermidine putrescine transport system, permease component I
HUT09_RS26495	COG1177	transmembrane transport
HUT09_RS26500	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HUT09_RS26530	COG2508	Transcriptional regulator
HUT09_RS26535	COG1012	belongs to the aldehyde dehydrogenase family
HUT09_RS26545	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
HUT09_RS26550	COG0750	zinc metalloprotease
HUT09_RS26555	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HUT09_RS26570	COG0442	prolyl-tRNA aminoacylation
HUT09_RS26590	COG0779	Required for maturation of 30S ribosomal subunits
HUT09_RS26605	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HUT09_RS26615	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HUT09_RS26620	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HUT09_RS26660	COG0601	transmembrane transport
HUT09_RS26665	COG0747	negative chemotaxis
HUT09_RS26670	COG0455	bacterial-type flagellum organization
HUT09_RS26690	COG3266	domain, Protein
HUT09_RS26695	COG1404	Belongs to the peptidase S8 family
HUT09_RS26725	COG1674	ftsk spoiiie
HUT09_RS26735	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HUT09_RS26740	COG1185	polyribonucleotide nucleotidyltransferase activity
HUT09_RS26745	COG0612	Peptidase, M16
HUT09_RS26750	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
HUT09_RS26770	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
HUT09_RS26775	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HUT09_RS26780	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HUT09_RS26820	COG1674	ftsk spoiiie
HUT09_RS26830	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HUT09_RS26840	COG1058	Belongs to the CinA family
HUT09_RS26840	COG1546	Belongs to the CinA family
HUT09_RS26845	COG1396	sequence-specific DNA binding
HUT09_RS26850	COG0783	Belongs to the Dps family
HUT09_RS26860	COG1028	Short-chain dehydrogenase reductase Sdr
HUT09_RS26865	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HUT09_RS26870	COG1201	RNA secondary structure unwinding
HUT09_RS26875	COG2207	Transcriptional regulator
HUT09_RS26875	COG1917	Cupin 2, conserved barrel domain protein
HUT09_RS26905	COG1028	Short-chain dehydrogenase reductase Sdr
HUT09_RS26910	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
HUT09_RS26910	COG1672	PFAM Archaeal ATPase
HUT09_RS26920	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HUT09_RS26945	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUT09_RS26950	COG0765	amino acid transport
HUT09_RS26955	COG0765	amino acid transport
HUT09_RS26960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUT09_RS26965	COG1126	abc transporter atp-binding protein
HUT09_RS26970	COG0745	RESPONSE REGULATOR receiver
HUT09_RS26975	COG2205	protein histidine kinase activity
HUT09_RS26980	COG2358	TRAP transporter, solute receptor (TAXI family
HUT09_RS26985	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HUT09_RS27000	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HUT09_RS27010	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HUT09_RS27015	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HUT09_RS27025	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HUT09_RS27065	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HUT09_RS27070	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HUT09_RS27075	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HUT09_RS27080	COG2045	Belongs to the ComB family
HUT09_RS27110	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HUT09_RS27140	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HUT09_RS27145	COG2186	Transcriptional regulator
HUT09_RS27150	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HUT09_RS27175	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HUT09_RS27180	COG4565	transcriptional regulatory protein
HUT09_RS27185	COG3290	protein histidine kinase activity
HUT09_RS27195	COG0372	Belongs to the citrate synthase family
HUT09_RS27200	COG0372	Belongs to the citrate synthase family
HUT09_RS27210	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HUT09_RS27215	COG0612	Peptidase, M16
HUT09_RS27230	COG1802	Transcriptional regulator
HUT09_RS27235	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUT09_RS27240	COG0045	succinate-CoA ligase (ADP-forming) activity
HUT09_RS27240	COG1042	CoA-binding domain protein
HUT09_RS27240	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HUT09_RS27255	COG1435	thymidine kinase activity
HUT09_RS27290	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
HUT09_RS27305	COG0745	RESPONSE REGULATOR receiver
HUT09_RS27310	COG2205	protein histidine kinase activity
HUT09_RS27335	COG0756	dUTP diphosphatase activity
HUT09_RS27385	COG0569	domain protein
HUT09_RS27390	COG0531	amino acid
HUT09_RS27395	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HUT09_RS27480	COG0464	growth
HUT09_RS27485	COG1404	Belongs to the peptidase S8 family
HUT09_RS27490	COG1674	ftsk spoiiie
HUT09_RS27510	COG4842	Belongs to the WXG100 family
HUT09_RS27555	COG1309	transcriptional regulator
HUT09_RS27565	COG1309	transcriptional regulator
HUT09_RS27570	COG2814	Major facilitator Superfamily
HUT09_RS27580	COG4401	Chorismate mutase type I
HUT09_RS27585	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
HUT09_RS27595	COG1028	Short-chain dehydrogenase reductase Sdr
HUT09_RS27600	COG4552	Acetyltransferase involved in intracellular survival and related
HUT09_RS27635	COG1309	transcriptional regulator
HUT09_RS27655	COG2192	nodulation
HUT09_RS27685	COG0505	Belongs to the CarA family
HUT09_RS27690	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HUT09_RS27695	COG1280	lysine exporter protein (LysE YggA)
HUT09_RS27700	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUT09_RS27710	COG3291	Pkd domain containing protein
HUT09_RS27755	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT09_RS27760	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT09_RS27780	COG1132	(ABC) transporter
HUT09_RS27780	COG2375	cellular response to nickel ion
HUT09_RS27790	COG0586	Pfam SNARE associated Golgi protein
HUT09_RS27805	COG1799	cell septum assembly
HUT09_RS27825	COG2040	homocysteine
HUT09_RS27835	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HUT09_RS27845	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HUT09_RS27850	COG0531	amino acid
HUT09_RS27860	COG1024	Enoyl-CoA hydratase
HUT09_RS27895	COG3592	Divergent 4Fe-4S mono-cluster
HUT09_RS27900	COG2111	Na H antiporter
HUT09_RS27900	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HUT09_RS27905	COG1006	Multisubunit Na H antiporter MnhC subunit
HUT09_RS27910	COG0651	ATP synthesis coupled electron transport
HUT09_RS27925	COG1320	monovalent cation:proton antiporter activity
HUT09_RS27940	COG0297	glycogen (starch) synthase activity
HUT09_RS27945	COG0489	protein tyrosine kinase activity
HUT09_RS27985	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
HUT09_RS27990	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HUT09_RS27995	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HUT09_RS28025	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HUT09_RS28035	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HUT09_RS28035	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HUT09_RS28065	COG1012	belongs to the aldehyde dehydrogenase family
HUT09_RS28070	COG0529	Catalyzes the synthesis of activated sulfate
HUT09_RS28070	COG2046	Belongs to the sulfate adenylyltransferase family
HUT09_RS28085	COG3903	Transcriptional regulator
HUT09_RS28085	COG3629	intracellular signal transduction
HUT09_RS28100	COG0697	spore germination
HUT09_RS28105	COG2814	Major facilitator Superfamily
HUT09_RS28110	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HUT09_RS28135	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HUT09_RS28145	COG0406	alpha-ribazole phosphatase activity
HUT09_RS28155	COG1653	transport
HUT09_RS28160	COG1175	transmembrane transport
HUT09_RS28165	COG0395	ABC-type sugar transport system, permease component
HUT09_RS28170	COG1940	carbohydrate kinase activity
HUT09_RS28175	COG4213	ABC transporter substrate-binding protein
HUT09_RS28185	COG4214	carbohydrate transport
HUT09_RS28190	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HUT09_RS28195	COG0531	amino acid
HUT09_RS28205	COG1316	TRANSCRIPTIONal
HUT09_RS28215	COG0438	transferase activity, transferring glycosyl groups
HUT09_RS28220	COG0438	transferase activity, transferring glycosyl groups
HUT09_RS28230	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HUT09_RS28235	COG0438	transferase activity, transferring glycosyl groups
HUT09_RS28240	COG1024	Enoyl-CoA hydratase
HUT09_RS28240	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUT09_RS28245	COG0183	Belongs to the thiolase family
HUT09_RS28265	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HUT09_RS28270	COG0446	pyridine nucleotide-disulphide oxidoreductase
HUT09_RS28280	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HUT09_RS28285	COG3253	May function as heme-dependent peroxidase
HUT09_RS28300	COG3220	belongs to the UPF0276 family
HUT09_RS28380	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HUT09_RS28385	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HUT09_RS28440	COG0483	inositol monophosphate 1-phosphatase activity
HUT09_RS28450	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HUT09_RS28465	COG1063	alcohol dehydrogenase
HUT09_RS28470	COG0156	8-amino-7-oxononanoate synthase activity
HUT09_RS28475	COG0583	DNA-binding transcription factor activity
HUT09_RS28485	COG0346	lactoylglutathione lyase activity
HUT09_RS28490	COG1072	(Pantothenic acid kinase))
HUT09_RS28505	COG2723	6-phospho-beta-galactosidase activity
HUT09_RS28560	COG1175	transmembrane transport
HUT09_RS28580	COG1404	Belongs to the peptidase S8 family
HUT09_RS28595	COG0596	Alpha beta hydrolase
HUT09_RS28605	COG1132	(ABC) transporter
HUT09_RS28610	COG1132	(ABC) transporter
HUT09_RS28615	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
HUT09_RS28625	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HUT09_RS28630	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
HUT09_RS28650	COG0529	Catalyzes the synthesis of activated sulfate
HUT09_RS28655	COG0175	sulfate reduction
HUT09_RS28680	COG1960	acyl-CoA dehydrogenase activity
HUT09_RS28700	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUT09_RS28705	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HUT09_RS28710	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HUT09_RS28715	COG0583	DNA-binding transcription factor activity
HUT09_RS28720	COG0183	Belongs to the thiolase family
HUT09_RS28765	COG1162	GTPase activity
HUT09_RS28790	COG0028	Belongs to the TPP enzyme family
HUT09_RS28815	COG1802	Transcriptional regulator
HUT09_RS28840	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HUT09_RS28845	COG2252	PERMEase
HUT09_RS28850	COG3608	succinylglutamate desuccinylase aspartoacylase
HUT09_RS28850	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HUT09_RS28920	COG0435	Glutathione S-transferase
HUT09_RS28935	COG2197	response regulator
HUT09_RS28940	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HUT09_RS28945	COG0318	PFAM AMP-dependent synthetase and ligase
HUT09_RS28965	COG3960	tartronate-semialdehyde synthase activity
HUT09_RS28980	COG3629	intracellular signal transduction
HUT09_RS28980	COG3903	Transcriptional regulator
HUT09_RS28990	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT09_RS29000	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HUT09_RS29010	COG0436	Aminotransferase
HUT09_RS29015	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HUT09_RS29030	COG0753	catalase activity
HUT09_RS29035	COG2084	Dehydrogenase
HUT09_RS29040	COG3622	Belongs to the hyi family
HUT09_RS29055	COG0395	ABC-type sugar transport system, permease component
HUT09_RS29060	COG1175	transmembrane transport
HUT09_RS29070	COG2188	Transcriptional regulator
HUT09_RS29075	COG2706	6-phosphogluconolactonase activity
HUT09_RS29095	COG2351	hydroxyisourate hydrolase activity
HUT09_RS29105	COG2233	PERMEase
HUT09_RS29115	COG2233	PERMEase
HUT09_RS29125	COG0596	Alpha beta hydrolase
HUT09_RS29150	COG1288	antiporter activity
HUT09_RS29155	COG1733	regulation of RNA biosynthetic process
HUT09_RS29175	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HUT09_RS29190	COG2197	response regulator
HUT09_RS29210	COG1414	Transcriptional regulator
HUT09_RS29215	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HUT09_RS29220	COG4266	Belongs to the allantoicase family
HUT09_RS29225	COG0656	L-ascorbic acid biosynthetic process
HUT09_RS29230	COG1028	Short-chain dehydrogenase reductase Sdr
HUT09_RS29255	COG2197	response regulator
HUT09_RS29270	COG0673	inositol 2-dehydrogenase activity
HUT09_RS29275	COG2188	Transcriptional regulator
HUT09_RS29280	COG1879	ABC-type sugar transport system periplasmic component
HUT09_RS29290	COG1129	ABC transporter
HUT09_RS29295	COG1940	carbohydrate kinase activity
HUT09_RS29310	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
HUT09_RS29325	COG1028	Short-chain dehydrogenase reductase Sdr
HUT09_RS29350	COG1126	abc transporter atp-binding protein
HUT09_RS29355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUT09_RS29360	COG0765	amino acid transport
HUT09_RS29365	COG0765	amino acid transport
HUT09_RS29385	COG0367	asparagine synthase
HUT09_RS29390	COG0477	Major facilitator Superfamily
HUT09_RS29405	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HUT09_RS29420	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUT09_RS29425	COG1028	Short-chain dehydrogenase reductase Sdr
HUT09_RS29435	COG0405	Gamma-glutamyltransferase
HUT09_RS29465	COG0667	Aldo Keto reductase
HUT09_RS29480	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HUT09_RS29500	COG1953	Uracil, thiamine, allantoin
HUT09_RS29550	COG0095	Lipoate-protein ligase
HUT09_RS29560	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HUT09_RS29570	COG1396	sequence-specific DNA binding
HUT09_RS29570	COG3800	Transcriptional regulator
HUT09_RS29590	COG1960	acyl-CoA dehydrogenase activity
HUT09_RS29625	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT09_RS29640	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HUT09_RS29655	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
HUT09_RS29695	COG1024	Enoyl-CoA hydratase
HUT09_RS29700	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT09_RS29715	COG1028	Short-chain dehydrogenase reductase Sdr
HUT09_RS29735	COG1028	Short-chain dehydrogenase reductase Sdr
HUT09_RS29740	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HUT09_RS29745	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HUT09_RS29755	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HUT09_RS29765	COG1131	(ABC) transporter
HUT09_RS29770	COG1024	Enoyl-CoA hydratase
HUT09_RS29800	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HUT09_RS29815	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HUT09_RS29830	COG1929	Belongs to the glycerate kinase type-1 family
HUT09_RS29850	COG0559	Belongs to the binding-protein-dependent transport system permease family
HUT09_RS29900	COG0688	phosphatidylethanolamine metabolic process
HUT09_RS29905	COG1960	acyl-CoA dehydrogenase activity
HUT09_RS29915	COG2301	Belongs to the HpcH HpaI aldolase family
HUT09_RS29920	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HUT09_RS29920	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HUT09_RS29925	COG0604	alcohol dehydrogenase
HUT09_RS29945	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUT09_RS29975	COG0583	DNA-binding transcription factor activity
HUT09_RS29980	COG0667	Aldo Keto reductase
HUT09_RS29990	COG2362	D-Aminopeptidase
HUT09_RS29995	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HUT09_RS30005	COG1619	proteins homologs of microcin C7 resistance protein MccF
HUT09_RS30020	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HUT09_RS30035	COG2226	methyltransferase
HUT09_RS30055	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
HUT09_RS30080	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HUT09_RS30095	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HUT09_RS30095	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HUT09_RS30105	COG2154	pterin-4-alpha-carbinolamine dehydratase
HUT09_RS30125	COG4106	trans-aconitate 2-methyltransferase activity
HUT09_RS30135	COG0656	L-ascorbic acid biosynthetic process
HUT09_RS30145	COG0583	DNA-binding transcription factor activity
HUT09_RS30160	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HUT09_RS30165	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HUT09_RS30175	COG1129	ABC transporter
HUT09_RS30180	COG1172	Belongs to the binding-protein-dependent transport system permease family
HUT09_RS30185	COG1879	ABC-type sugar transport system periplasmic component
HUT09_RS30190	COG0673	inositol 2-dehydrogenase activity
HUT09_RS30210	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
HUT09_RS30275	COG1129	ABC transporter
HUT09_RS30285	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUT09_RS30290	COG1869	D-ribose catabolic process
HUT09_RS30300	COG0714	Associated with various cellular activities
HUT09_RS30330	COG5000	phosphorelay sensor kinase activity
HUT09_RS30330	COG5002	protein histidine kinase activity
HUT09_RS30335	COG0745	RESPONSE REGULATOR receiver
HUT09_RS30360	COG1012	belongs to the aldehyde dehydrogenase family
HUT09_RS30370	COG0517	IMP dehydrogenase activity
HUT09_RS30370	COG4175	Glycine betaine
HUT09_RS30375	COG4176	ABC-type proline glycine betaine transport system permease component
HUT09_RS30395	COG2985	domain, Protein
HUT09_RS30395	COG0569	domain protein
HUT09_RS30410	COG1070	Carbohydrate kinase
HUT09_RS30420	COG1940	carbohydrate kinase activity
HUT09_RS30445	COG1289	transmembrane transporter activity
HUT09_RS30450	COG1846	Transcriptional regulator
HUT09_RS30480	COG2124	cytochrome p450
HUT09_RS30485	COG1486	melibiose metabolic process
HUT09_RS30525	COG3012	SEC-C Motif Domain Protein
HUT09_RS30570	COG1127	ABC transporter
HUT09_RS30580	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HUT09_RS30605	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HUT09_RS30640	COG2208	phosphoserine phosphatase activity
HUT09_RS30640	COG2770	Histidine kinase
HUT09_RS30660	COG2326	polyphosphate kinase activity
HUT09_RS30665	COG1793	dna ligase
HUT09_RS30695	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HUT09_RS30715	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HUT09_RS30720	COG1116	anion transmembrane transporter activity
HUT09_RS30725	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HUT09_RS30730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT09_RS30750	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HUT09_RS30755	COG0488	(ABC) transporter
HUT09_RS30770	COG1515	deoxyribonuclease V activity
HUT09_RS30780	COG3268	Saccharopine dehydrogenase
HUT09_RS30785	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HUT09_RS30790	COG1960	acyl-CoA dehydrogenase activity
HUT09_RS30795	COG0183	Belongs to the thiolase family
HUT09_RS30800	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUT09_RS30800	COG1024	Enoyl-CoA hydratase
HUT09_RS30805	COG0789	Transcriptional regulator
HUT09_RS30830	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HUT09_RS30840	COG0488	(ABC) transporter
HUT09_RS30845	COG2183	response to ionizing radiation
HUT09_RS30855	COG4977	sequence-specific DNA binding
HUT09_RS30865	COG1024	Enoyl-CoA hydratase
HUT09_RS30880	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
HUT09_RS30910	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HUT09_RS30930	COG1134	teichoic acid transport
HUT09_RS30935	COG1562	ergosterol biosynthetic process
HUT09_RS30945	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HUT09_RS30955	COG1657	PFAM Prenyltransferase squalene oxidase
HUT09_RS30985	COG2365	Tyrosine phosphatase family
HUT09_RS30990	COG0739	heme binding
HUT09_RS30995	COG2755	lipolytic protein G-D-S-L family
HUT09_RS31045	COG3467	pyridoxamine 5'-phosphate
HUT09_RS31085	COG1609	Transcriptional regulator
HUT09_RS31090	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HUT09_RS31100	COG1116	anion transmembrane transporter activity
HUT09_RS31130	COG3958	Transketolase
HUT09_RS31135	COG3959	Transketolase, thiamine diphosphate binding domain
HUT09_RS31180	COG2226	methyltransferase
HUT09_RS31185	COG1132	(ABC) transporter
HUT09_RS31245	COG0542	response to heat
HUT09_RS31265	COG3511	phospholipase C
HUT09_RS31275	COG2197	response regulator
HUT09_RS31280	COG3851	Histidine kinase
HUT09_RS31290	COG2186	Transcriptional regulator
HUT09_RS31295	COG0247	lactate metabolic process
HUT09_RS31300	COG1139	Iron-sulfur cluster binding protein
HUT09_RS31305	COG1556	Lactate utilization protein
HUT09_RS31325	COG1672	PFAM Archaeal ATPase
HUT09_RS31325	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
HUT09_RS31335	COG3046	protein related to deoxyribodipyrimidine photolyase
HUT09_RS31340	COG1533	DNA photolyase activity
HUT09_RS31405	COG1902	pentaerythritol trinitrate reductase activity
HUT09_RS31405	COG0446	pyridine nucleotide-disulphide oxidoreductase
HUT09_RS31420	COG2409	Drug exporters of the RND superfamily
HUT09_RS31425	COG1846	Transcriptional regulator
HUT09_RS31485	COG1233	COG1233 Phytoene dehydrogenase and related
HUT09_RS31490	COG2130	NADP-dependent
HUT09_RS31500	COG0671	phosphoesterase, PA-phosphatase related
HUT09_RS31515	COG2837	iron assimilation
HUT09_RS31520	COG0672	)-iron permease
HUT09_RS31525	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HUT09_RS31540	COG1051	belongs to the nudix hydrolase family
HUT09_RS31555	COG0019	diaminopimelate decarboxylase activity
HUT09_RS31565	COG2837	iron assimilation
HUT09_RS31570	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HUT09_RS31585	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HUT09_RS31590	COG2272	Belongs to the type-B carboxylesterase lipase family
HUT09_RS31595	COG0789	Transcriptional regulator
HUT09_RS31635	COG2723	6-phospho-beta-galactosidase activity
HUT09_RS31640	COG0395	ABC-type sugar transport system, permease component
HUT09_RS31645	COG1175	transmembrane transport
HUT09_RS31655	COG1940	carbohydrate kinase activity
HUT09_RS31665	COG1652	LysM domain
HUT09_RS31700	COG0784	Response regulator, receiver
HUT09_RS31705	COG4251	negative regulation of phosphorylation
HUT09_RS31710	COG2201	protein-glutamate methylesterase activity
HUT09_RS31715	COG1191	sigma factor activity
HUT09_RS31760	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HUT09_RS31780	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HUT09_RS31785	COG3275	phosphorelay sensor kinase activity
HUT09_RS31860	COG0583	DNA-binding transcription factor activity
HUT09_RS31870	COG1053	succinate dehydrogenase
HUT09_RS31875	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HUT09_RS31885	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT09_RS31895	COG3360	Dodecin
HUT09_RS31900	COG2182	Extracellular solute-binding protein
HUT09_RS31915	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
HUT09_RS31920	COG0121	glutamine amidotransferase
HUT09_RS31925	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HUT09_RS31930	COG3572	ergothioneine biosynthetic process
HUT09_RS31950	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HUT09_RS31955	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HUT09_RS31960	COG2066	Belongs to the glutaminase family
HUT09_RS31965	COG0297	glycogen (starch) synthase activity
HUT09_RS31970	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HUT09_RS31980	COG0477	Major facilitator Superfamily
HUT09_RS31990	COG3693	PFAM glycoside hydrolase, family 10
HUT09_RS32025	COG0300	oxidoreductase activity
HUT09_RS32030	COG2207	Transcriptional regulator
HUT09_RS32035	COG0657	acetylesterase activity
HUT09_RS32060	COG1834	amidinotransferase
HUT09_RS32075	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HUT09_RS32090	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HUT09_RS32115	COG1028	Short-chain dehydrogenase reductase Sdr
HUT09_RS32160	COG2207	Transcriptional regulator
HUT09_RS32165	COG2223	nitrite transmembrane transporter activity
HUT09_RS32190	COG0747	negative chemotaxis
HUT09_RS32195	COG0601	transmembrane transport
HUT09_RS32200	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HUT09_RS32205	COG0444	Belongs to the ABC transporter superfamily
HUT09_RS32210	COG4608	Belongs to the ABC transporter superfamily
HUT09_RS32215	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT09_RS32220	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUT09_RS32230	COG0431	NADPH-dependent FMN reductase
HUT09_RS32250	COG1609	Transcriptional regulator
HUT09_RS32265	COG1172	Belongs to the binding-protein-dependent transport system permease family
HUT09_RS32270	COG1129	ABC transporter
HUT09_RS32280	COG1028	Short-chain dehydrogenase reductase Sdr
HUT09_RS32280	COG3347	Dehydrogenase
HUT09_RS32285	COG1070	Carbohydrate kinase
HUT09_RS32290	COG3250	beta-galactosidase activity
HUT09_RS32305	COG1120	ATPase activity
HUT09_RS32320	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HUT09_RS32330	COG0254	rRNA binding
HUT09_RS32335	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HUT09_RS32340	COG0227	Belongs to the bacterial ribosomal protein bL28 family
HUT09_RS32345	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HUT09_RS32365	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT09_RS32370	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT09_RS32375	COG1120	ATPase activity
HUT09_RS32405	COG1132	(ABC) transporter
HUT09_RS32450	COG0438	transferase activity, transferring glycosyl groups
HUT09_RS32500	COG1174	glycine betaine transport
HUT09_RS32505	COG1174	glycine betaine transport
HUT09_RS32520	COG1125	glycine betaine transport
HUT09_RS32520	COG0517	IMP dehydrogenase activity
HUT09_RS32530	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HUT09_RS32550	COG1960	acyl-CoA dehydrogenase activity
HUT09_RS32555	COG1960	acyl-CoA dehydrogenase activity
HUT09_RS32570	COG0601	transmembrane transport
HUT09_RS32575	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HUT09_RS32580	COG0444	Belongs to the ABC transporter superfamily
HUT09_RS32645	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
HUT09_RS32645	COG1796	DNA polymerase
HUT09_RS32735	COG1278	Cold shock
HUT09_RS32750	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
HUT09_RS32755	COG0693	protein deglycase activity
HUT09_RS32785	COG2267	carboxylic ester hydrolase activity
HUT09_RS32790	COG4044	May play a role in the intracellular transport of hydrophobic ligands
HUT09_RS32835	COG5297	Belongs to the glycosyl hydrolase family 6
HUT09_RS32840	COG2175	clavaminate synthase activity
HUT09_RS32905	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HUT09_RS32925	COG1012	belongs to the aldehyde dehydrogenase family
HUT09_RS32945	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HUT09_RS32950	COG3239	Fatty acid desaturase
HUT09_RS32990	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HUT09_RS33000	COG0640	Transcriptional regulator
HUT09_RS33015	COG2018	Roadblock/LC7 domain
HUT09_RS33040	COG1024	Enoyl-CoA hydratase
HUT09_RS33080	COG1595	DNA-templated transcription, initiation
HUT09_RS33100	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HUT09_RS33115	COG2340	Cysteine-rich secretory protein family
HUT09_RS33145	COG0583	DNA-binding transcription factor activity
HUT09_RS33165	COG0488	(ABC) transporter
HUT09_RS33190	COG0009	L-threonylcarbamoyladenylate synthase
HUT09_RS33245	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
HUT09_RS33265	COG0142	geranyltranstransferase activity
HUT09_RS33285	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HUT09_RS33300	COG1891	lyase activity
HUT09_RS33310	COG2890	protein-(glutamine-N5) methyltransferase activity
HUT09_RS33335	COG2318	DinB family
HUT09_RS33360	COG0395	ABC-type sugar transport system, permease component
HUT09_RS33365	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HUT09_RS33370	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HUT09_RS33380	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HUT09_RS33405	COG0583	DNA-binding transcription factor activity
HUT09_RS33410	COG2367	Beta-lactamase
HUT09_RS33475	COG4221	oxidoreductase activity
HUT09_RS33480	COG0596	Alpha beta hydrolase
HUT09_RS33510	COG0179	Fumarylacetoacetate (FAA) hydrolase
HUT09_RS33515	COG0318	PFAM AMP-dependent synthetase and ligase
HUT09_RS33530	COG0477	Major facilitator Superfamily
HUT09_RS33550	COG1012	belongs to the aldehyde dehydrogenase family
HUT09_RS33575	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HUT09_RS33585	COG3548	integral membrane protein
HUT09_RS33595	COG1191	sigma factor activity
HUT09_RS33640	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HUT09_RS33670	COG1366	Belongs to the anti-sigma-factor antagonist family
HUT09_RS33675	COG2208	phosphoserine phosphatase activity
HUT09_RS33675	COG2770	Histidine kinase
HUT09_RS33705	COG0456	acetyltransferase
HUT09_RS33720	COG0640	Transcriptional regulator
HUT09_RS33755	COG1120	ATPase activity
HUT09_RS33760	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HUT09_RS33800	COG3385	transposase activity
HUT09_RS33845	COG0105	UTP biosynthetic process
HUT09_RS33990	COG4974	Belongs to the 'phage' integrase family
HUT09_RS34040	COG1191	sigma factor activity
HUT09_RS34205	COG0659	secondary active sulfate transmembrane transporter activity
HUT09_RS34215	COG2015	COG2015, Alkyl sulfatase and related hydrolases
HUT09_RS34335	COG3848	Pyruvate phosphate dikinase
HUT09_RS34335	COG0574	Belongs to the PEP-utilizing enzyme family
HUT09_RS34350	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
HUT09_RS34355	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HUT09_RS34360	COG2226	methyltransferase
HUT09_RS34415	COG3385	transposase activity
HUT09_RS34455	COG2124	cytochrome p450
HUT09_RS34495	COG0438	transferase activity, transferring glycosyl groups
HUT09_RS34510	COG2226	methyltransferase
HUT09_RS34525	COG0656	L-ascorbic acid biosynthetic process
HUT09_RS34575	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HUT09_RS34590	COG1028	Short-chain dehydrogenase reductase Sdr
HUT09_RS34610	COG2890	protein-(glutamine-N5) methyltransferase activity
HUT09_RS34660	COG0531	amino acid
HUT09_RS34685	COG2409	Drug exporters of the RND superfamily
HUT09_RS34690	COG4585	Histidine kinase
HUT09_RS34695	COG2197	response regulator
HUT09_RS34705	COG2197	response regulator
HUT09_RS34750	COG4124	Belongs to the glycosyl hydrolase 26 family
HUT09_RS34760	COG1482	cell wall glycoprotein biosynthetic process
HUT09_RS34780	COG0395	ABC-type sugar transport system, permease component
HUT09_RS34785	COG1175	transmembrane transport
HUT09_RS34880	COG1191	sigma factor activity
HUT09_RS34900	COG3629	intracellular signal transduction
HUT09_RS34900	COG3903	Transcriptional regulator
HUT09_RS34940	COG0069	glutamate synthase activity
HUT09_RS34970	COG0596	Alpha beta hydrolase
HUT09_RS34980	COG1366	Belongs to the anti-sigma-factor antagonist family
HUT09_RS34990	COG1191	sigma factor activity
HUT09_RS35010	COG2172	sigma factor antagonist activity
HUT09_RS35015	COG1366	Belongs to the anti-sigma-factor antagonist family
HUT09_RS35020	COG1366	Belongs to the anti-sigma-factor antagonist family
HUT09_RS35065	COG1278	Cold shock
HUT09_RS35070	COG0513	Belongs to the DEAD box helicase family
HUT09_RS35180	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HUT09_RS35205	COG0583	DNA-binding transcription factor activity
HUT09_RS35210	COG2814	Major facilitator Superfamily
HUT09_RS35215	COG0789	Transcriptional regulator
HUT09_RS35225	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
HUT09_RS35235	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
HUT09_RS35240	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
HUT09_RS35245	COG0367	asparagine synthase
HUT09_RS35260	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
HUT09_RS35280	COG1132	(ABC) transporter
HUT09_RS35320	COG1960	acyl-CoA dehydrogenase activity
HUT09_RS35325	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT09_RS35335	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HUT09_RS35460	COG0463	Glycosyl transferase, family 2
HUT09_RS35515	COG3328	transposase activity
HUT09_RS35520	COG3507	Belongs to the glycosyl hydrolase 43 family
HUT09_RS35520	COG2382	esterase
HUT09_RS35520	COG3693	PFAM glycoside hydrolase, family 10
HUT09_RS35540	COG3291	Pkd domain containing protein
HUT09_RS35545	COG4608	Belongs to the ABC transporter superfamily
HUT09_RS35555	COG0601	transmembrane transport
HUT09_RS35560	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HUT09_RS35565	COG0747	negative chemotaxis
HUT09_RS35570	COG0006	proline dipeptidase activity
HUT09_RS35575	COG1802	Transcriptional regulator
HUT09_RS35580	COG2423	ornithine cyclodeaminase activity
HUT09_RS35585	COG3938	Belongs to the proline racemase family
HUT09_RS35590	COG3938	Belongs to the proline racemase family
HUT09_RS35600	COG0446	pyridine nucleotide-disulphide oxidoreductase
HUT09_RS35610	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HUT09_RS35690	COG2319	Wd-40 repeat
HUT09_RS35690	COG4249	Peptidase C14 caspase catalytic subunit p20
HUT09_RS35780	COG0667	Aldo Keto reductase
HUT09_RS35800	COG0300	oxidoreductase activity
HUT09_RS35830	COG3251	PFAM MbtH domain protein
HUT09_RS35865	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
HUT09_RS35875	COG2801	Transposase and inactivated derivatives
HUT09_RS35890	COG3903	Transcriptional regulator
HUT09_RS35890	COG3629	intracellular signal transduction
HUT09_RS35945	COG0259	pyridoxamine-phosphate oxidase activity
HUT09_RS35990	COG0443	Heat shock 70 kDa protein
HUT09_RS36050	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HUT09_RS36055	COG1518	maintenance of DNA repeat elements
HUT09_RS36205	COG0667	Aldo Keto reductase
HUT09_RS36260	COG1335	isochorismatase
HUT09_RS36280	COG2814	Major facilitator Superfamily
HUT09_RS36385	COG1192	Involved in chromosome partitioning
HUT09_RS36415	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HUT09_RS36425	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
HUT09_RS36440	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HUT09_RS36445	COG0587	DNA-directed DNA polymerase activity
HUT09_RS36460	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HUT09_RS36570	COG2770	Histidine kinase
HUT09_RS36570	COG2208	phosphoserine phosphatase activity
HUT09_RS36625	COG3547	Transposase (IS116 IS110 IS902 family)
HUT09_RS36640	COG5297	Belongs to the glycosyl hydrolase family 6
HUT09_RS36640	COG4733	cellulase activity
HUT09_RS36685	COG0693	protein deglycase activity
HUT09_RS36690	COG0656	L-ascorbic acid biosynthetic process
HUT09_RS36700	COG1733	regulation of RNA biosynthetic process
HUT09_RS36835	COG4221	oxidoreductase activity
HUT09_RS36840	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
HUT09_RS36895	COG0659	secondary active sulfate transmembrane transporter activity
HUT09_RS36905	COG2015	COG2015, Alkyl sulfatase and related hydrolases
HUT09_RS36960	COG0305	Participates in initiation and elongation during chromosome replication
HUT09_RS37030	COG1475	DNA binding
HUT09_RS37135	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HUT09_RS37225	COG0277	FAD linked oxidase domain protein
HUT09_RS37260	COG1607	acyl-coa hydrolase
HUT09_RS37285	COG1401	restriction endodeoxyribonuclease activity
HUT09_RS37355	COG0242	peptide deformylase activity
HUT09_RS37605	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HUT09_RS37760	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HUT09_RS38005	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HUT09_RS38005	COG0515	serine threonine protein kinase
HUT09_RS38060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components