locus-tag	class	description
K7I03_RS00020	COG3547	Transposase (IS116 IS110 IS902 family)
K7I03_RS00055	COG0494	nUDIX hydrolase
K7I03_RS00070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K7I03_RS00090	COG1960	acyl-CoA dehydrogenase activity
K7I03_RS00100	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
K7I03_RS00110	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
K7I03_RS00120	COG1181	Belongs to the D-alanine--D-alanine ligase family
K7I03_RS00165	COG2197	response regulator
K7I03_RS00195	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
K7I03_RS00195	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
K7I03_RS00270	COG2207	Transcriptional regulator
K7I03_RS00275	COG0596	Alpha beta hydrolase
K7I03_RS00290	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
K7I03_RS00310	COG1595	DNA-templated transcription, initiation
K7I03_RS00330	COG0531	amino acid
K7I03_RS00335	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
K7I03_RS00335	COG1672	PFAM Archaeal ATPase
K7I03_RS00340	COG1819	glycosyl
K7I03_RS00345	COG3321	synthase
K7I03_RS00345	COG0604	alcohol dehydrogenase
K7I03_RS00350	COG0604	alcohol dehydrogenase
K7I03_RS00350	COG3321	synthase
K7I03_RS00365	COG2267	carboxylic ester hydrolase activity
K7I03_RS00385	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
K7I03_RS00390	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K7I03_RS00410	COG4865	methylaspartate mutase activity
K7I03_RS00415	COG3321	synthase
K7I03_RS00415	COG0604	alcohol dehydrogenase
K7I03_RS00430	COG3321	synthase
K7I03_RS00430	COG0604	alcohol dehydrogenase
K7I03_RS00450	COG0477	Major facilitator Superfamily
K7I03_RS00455	COG2197	response regulator
K7I03_RS00465	COG1136	(ABC) transporter
K7I03_RS00480	COG0318	PFAM AMP-dependent synthetase and ligase
K7I03_RS00485	COG0445	tRNA wobble uridine modification
K7I03_RS00490	COG1755	Isoprenylcysteine carboxyl methyltransferase
K7I03_RS00505	COG0655	NAD(P)H dehydrogenase (quinone) activity
K7I03_RS00510	COG1960	acyl-CoA dehydrogenase activity
K7I03_RS00535	COG2072	flavoprotein involved in K transport
K7I03_RS00580	COG0583	DNA-binding transcription factor activity
K7I03_RS00615	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K7I03_RS00660	COG0714	Associated with various cellular activities
K7I03_RS00695	COG0154	amidase activity
K7I03_RS00715	COG1028	Short-chain dehydrogenase reductase Sdr
K7I03_RS00720	COG2814	Major facilitator Superfamily
K7I03_RS00745	COG0668	transmembrane transport
K7I03_RS00760	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
K7I03_RS00765	COG0604	alcohol dehydrogenase
K7I03_RS00825	COG2226	methyltransferase
K7I03_RS00900	COG1695	Transcriptional regulator
K7I03_RS00910	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
K7I03_RS00945	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K7I03_RS00950	COG1960	acyl-CoA dehydrogenase activity
K7I03_RS00970	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K7I03_RS00970	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K7I03_RS00995	COG2271	Major facilitator Superfamily
K7I03_RS01045	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
K7I03_RS01055	COG1595	DNA-templated transcription, initiation
K7I03_RS01110	COG1113	amino acid transport
K7I03_RS01130	COG1733	regulation of RNA biosynthetic process
K7I03_RS01140	COG4585	Histidine kinase
K7I03_RS01155	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
K7I03_RS01195	COG0346	lactoylglutathione lyase activity
K7I03_RS01250	COG3511	phospholipase C
K7I03_RS01280	COG1191	sigma factor activity
K7I03_RS01360	COG0326	Molecular chaperone. Has ATPase activity
K7I03_RS01375	COG2239	Acts as a magnesium transporter
K7I03_RS01385	COG1309	transcriptional regulator
K7I03_RS01395	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
K7I03_RS01395	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
K7I03_RS01400	COG1796	DNA polymerase
K7I03_RS01400	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
K7I03_RS01405	COG1357	PFAM Pentapeptide repeats (8 copies)
K7I03_RS01410	COG2124	cytochrome p450
K7I03_RS01445	COG3268	Saccharopine dehydrogenase
K7I03_RS01455	COG1063	alcohol dehydrogenase
K7I03_RS01460	COG0156	8-amino-7-oxononanoate synthase activity
K7I03_RS01495	COG1609	Transcriptional regulator
K7I03_RS01500	COG1129	ABC transporter
K7I03_RS01510	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
K7I03_RS01520	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
K7I03_RS01525	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
K7I03_RS01530	COG2409	Drug exporters of the RND superfamily
K7I03_RS01540	COG1755	Isoprenylcysteine carboxyl methyltransferase
K7I03_RS01550	COG0154	amidase activity
K7I03_RS01555	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
K7I03_RS01590	COG1902	pentaerythritol trinitrate reductase activity
K7I03_RS01590	COG0446	pyridine nucleotide-disulphide oxidoreductase
K7I03_RS01620	COG0784	Response regulator, receiver
K7I03_RS01630	COG4251	negative regulation of phosphorylation
K7I03_RS01665	COG2197	response regulator
K7I03_RS01670	COG4585	Histidine kinase
K7I03_RS01690	COG0475	glutathione-regulated potassium exporter activity
K7I03_RS01730	COG2826	transposase and inactivated derivatives, IS30 family
K7I03_RS01750	COG1970	mechanosensitive ion channel activity
K7I03_RS01760	COG0477	Major facilitator Superfamily
K7I03_RS01785	COG1064	alcohol dehydrogenase
K7I03_RS01800	COG4336	lyase activity
K7I03_RS01825	COG3979	chitinase
K7I03_RS01830	COG0586	Pfam SNARE associated Golgi protein
K7I03_RS01845	COG3226	Transcriptional regulator
K7I03_RS01860	COG0477	Major facilitator Superfamily
K7I03_RS01870	COG1819	glycosyl
K7I03_RS01910	COG3226	Transcriptional regulator
K7I03_RS01925	COG0604	alcohol dehydrogenase
K7I03_RS01925	COG3321	synthase
K7I03_RS01930	COG3321	synthase
K7I03_RS01930	COG1028	Short-chain dehydrogenase reductase Sdr
K7I03_RS01930	COG0604	alcohol dehydrogenase
K7I03_RS01975	COG1960	acyl-CoA dehydrogenase activity
K7I03_RS01990	COG0242	peptide deformylase activity
K7I03_RS02000	COG3442	glutamine amidotransferase
K7I03_RS02005	COG0205	6-phosphofructokinase activity
K7I03_RS02045	COG3387	PFAM Glycoside hydrolase 15-related
K7I03_RS02085	COG0829	nickel cation binding
K7I03_RS02090	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
K7I03_RS02100	COG0804	urea catabolic process
K7I03_RS02105	COG0832	Belongs to the urease beta subunit family
K7I03_RS02110	COG0831	urea catabolic process
K7I03_RS02125	COG1687	branched-chain amino acid
K7I03_RS02155	COG0740	serine-type endopeptidase activity
K7I03_RS02165	COG0791	NLP P60 protein
K7I03_RS02190	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
K7I03_RS02195	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
K7I03_RS02200	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
K7I03_RS02205	COG2226	methyltransferase
K7I03_RS02235	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
K7I03_RS02240	COG3663	DNA glycosylase
K7I03_RS02250	COG1940	carbohydrate kinase activity
K7I03_RS02255	COG2188	Transcriptional regulator
K7I03_RS02260	COG2267	carboxylic ester hydrolase activity
K7I03_RS02280	COG4585	Histidine kinase
K7I03_RS02285	COG2197	response regulator
K7I03_RS02300	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K7I03_RS02305	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
K7I03_RS02345	COG1522	sequence-specific DNA binding
K7I03_RS02350	COG0419	ATPase involved in DNA repair
K7I03_RS02355	COG0420	3'-5' exonuclease activity
K7I03_RS02370	COG1739	Uncharacterized protein family UPF0029
K7I03_RS02400	COG1832	CoA-binding protein
K7I03_RS02500	COG0110	maltose O-acetyltransferase activity
K7I03_RS02530	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
K7I03_RS02535	COG0477	Major facilitator Superfamily
K7I03_RS02540	COG2264	protein methyltransferase activity
K7I03_RS02545	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K7I03_RS02590	COG1309	transcriptional regulator
K7I03_RS02610	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
K7I03_RS02625	COG2706	6-phosphogluconolactonase activity
K7I03_RS02635	COG1522	sequence-specific DNA binding
K7I03_RS02660	COG2072	flavoprotein involved in K transport
K7I03_RS02670	COG1139	Iron-sulfur cluster binding protein
K7I03_RS02675	COG1556	Lactate utilization protein
K7I03_RS02685	COG1132	(ABC) transporter
K7I03_RS02690	COG1846	Transcriptional regulator
K7I03_RS02705	COG1132	(ABC) transporter
K7I03_RS02715	COG1733	regulation of RNA biosynthetic process
K7I03_RS02750	COG2018	Roadblock/LC7 domain
K7I03_RS02765	COG3511	phospholipase C
K7I03_RS02805	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
K7I03_RS02810	COG0494	nUDIX hydrolase
K7I03_RS02840	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
K7I03_RS02840	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
K7I03_RS02855	COG1124	(ABC) transporter
K7I03_RS02860	COG0444	Belongs to the ABC transporter superfamily
K7I03_RS02865	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K7I03_RS02870	COG0601	transmembrane transport
K7I03_RS02880	COG1609	Transcriptional regulator
K7I03_RS02890	COG1175	transmembrane transport
K7I03_RS02895	COG0395	ABC-type sugar transport system, permease component
K7I03_RS02935	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
K7I03_RS02945	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
K7I03_RS02960	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
K7I03_RS03010	COG2205	protein histidine kinase activity
K7I03_RS03015	COG0745	RESPONSE REGULATOR receiver
K7I03_RS03020	COG1960	acyl-CoA dehydrogenase activity
K7I03_RS03040	COG1262	PFAM Formylglycine-generating sulfatase enzyme
K7I03_RS03045	COG0121	glutamine amidotransferase
K7I03_RS03050	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
K7I03_RS03070	COG3360	Dodecin
K7I03_RS03110	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
K7I03_RS03120	COG2272	Belongs to the type-B carboxylesterase lipase family
K7I03_RS03160	COG3845	ABC transporter
K7I03_RS03175	COG3537	Alpha-1,2-mannosidase
K7I03_RS03180	COG0531	amino acid
K7I03_RS03185	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
K7I03_RS03205	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
K7I03_RS03210	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
K7I03_RS03215	COG0531	amino acid
K7I03_RS03320	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
K7I03_RS03355	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
K7I03_RS03375	COG1191	sigma factor activity
K7I03_RS03385	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
K7I03_RS03420	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
K7I03_RS03430	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
K7I03_RS03455	COG3903	Transcriptional regulator
K7I03_RS03455	COG3629	intracellular signal transduction
K7I03_RS03475	COG1012	belongs to the aldehyde dehydrogenase family
K7I03_RS03485	COG0367	asparagine synthase
K7I03_RS03495	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
K7I03_RS03500	COG1262	PFAM Formylglycine-generating sulfatase enzyme
K7I03_RS03505	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
K7I03_RS03510	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
K7I03_RS03515	COG0436	Aminotransferase
K7I03_RS03520	COG1028	Short-chain dehydrogenase reductase Sdr
K7I03_RS03580	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
K7I03_RS03590	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
K7I03_RS03600	COG0784	Response regulator, receiver
K7I03_RS03600	COG5002	protein histidine kinase activity
K7I03_RS03600	COG2205	protein histidine kinase activity
K7I03_RS03610	COG0492	ferredoxin-NADP+ reductase activity
K7I03_RS03650	COG2986	histidine ammonia-lyase
K7I03_RS03660	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
K7I03_RS03675	COG1028	Short-chain dehydrogenase reductase Sdr
K7I03_RS03705	COG0501	Belongs to the peptidase M48B family
K7I03_RS03710	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
K7I03_RS03745	COG1012	belongs to the aldehyde dehydrogenase family
K7I03_RS03750	COG0515	serine threonine protein kinase
K7I03_RS03765	COG1132	(ABC) transporter
K7I03_RS03775	COG2197	response regulator
K7I03_RS03800	COG0242	peptide deformylase activity
K7I03_RS03815	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K7I03_RS03820	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K7I03_RS03845	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K7I03_RS03850	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K7I03_RS03865	COG1028	Short-chain dehydrogenase reductase Sdr
K7I03_RS03870	COG1309	transcriptional regulator
K7I03_RS03890	COG4221	oxidoreductase activity
K7I03_RS03930	COG0583	DNA-binding transcription factor activity
K7I03_RS03940	COG1024	Enoyl-CoA hydratase
K7I03_RS03950	COG1250	3-hydroxyacyl-CoA dehydrogenase
K7I03_RS03955	COG1960	acyl-CoA dehydrogenase activity
K7I03_RS03980	COG2234	aminopeptidase activity
K7I03_RS03985	COG0519	Catalyzes the synthesis of GMP from XMP
K7I03_RS04025	COG1028	Short-chain dehydrogenase reductase Sdr
K7I03_RS04040	COG0247	lactate metabolic process
K7I03_RS04040	COG0277	FAD linked oxidase domain protein
K7I03_RS04045	COG1007	ATP synthesis coupled electron transport
K7I03_RS04050	COG1006	Multisubunit Na H antiporter MnhC subunit
K7I03_RS04055	COG2111	Na H antiporter
K7I03_RS04095	COG1129	ABC transporter
K7I03_RS04095	COG0842	Transport permease protein
K7I03_RS04100	COG0113	porphobilinogen synthase activity
K7I03_RS04105	COG0181	hydroxymethylbilane synthase activity
K7I03_RS04110	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
K7I03_RS04115	COG0408	coproporphyrinogen oxidase activity
K7I03_RS04120	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
K7I03_RS04145	COG2409	Drug exporters of the RND superfamily
K7I03_RS04150	COG2814	Major facilitator Superfamily
K7I03_RS04155	COG1028	Short-chain dehydrogenase reductase Sdr
K7I03_RS04170	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K7I03_RS04175	COG0028	Belongs to the TPP enzyme family
K7I03_RS04195	COG0604	alcohol dehydrogenase
K7I03_RS04195	COG1028	Short-chain dehydrogenase reductase Sdr
K7I03_RS04195	COG3321	synthase
K7I03_RS04210	COG2409	Drug exporters of the RND superfamily
K7I03_RS04220	COG3290	protein histidine kinase activity
K7I03_RS04225	COG5001	Diguanylate cyclase
K7I03_RS04240	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
K7I03_RS04265	COG1024	Enoyl-CoA hydratase
K7I03_RS04280	COG1742	UPF0060 membrane protein
K7I03_RS04290	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
K7I03_RS04335	COG0531	amino acid
K7I03_RS04355	COG1802	Transcriptional regulator
K7I03_RS04365	COG3938	Belongs to the proline racemase family
K7I03_RS04385	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K7I03_RS04400	COG0006	proline dipeptidase activity
K7I03_RS04415	COG0386	Belongs to the glutathione peroxidase family
K7I03_RS04440	COG0667	Aldo Keto reductase
K7I03_RS04455	COG2814	Major facilitator Superfamily
K7I03_RS04460	COG0243	molybdopterin cofactor binding
K7I03_RS04500	COG2197	response regulator
K7I03_RS04565	COG0488	(ABC) transporter
K7I03_RS04570	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
K7I03_RS04585	COG0657	acetylesterase activity
K7I03_RS04595	COG1529	Aldehyde oxidase and xanthine dehydrogenase
K7I03_RS04600	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
K7I03_RS04605	COG2080	2 iron, 2 sulfur cluster binding
K7I03_RS04620	COG0488	(ABC) transporter
K7I03_RS04645	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
K7I03_RS04675	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K7I03_RS04755	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
K7I03_RS04765	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K7I03_RS04765	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
K7I03_RS04775	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
K7I03_RS04830	COG0823	Involved in the tonB-independent uptake of proteins
K7I03_RS04870	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
K7I03_RS04895	COG2755	lipolytic protein G-D-S-L family
K7I03_RS04910	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
K7I03_RS04915	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
K7I03_RS04930	COG1657	PFAM Prenyltransferase squalene oxidase
K7I03_RS04940	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
K7I03_RS04950	COG1562	ergosterol biosynthetic process
K7I03_RS04955	COG1134	teichoic acid transport
K7I03_RS04955	COG1388	LysM domain
K7I03_RS05000	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
K7I03_RS05010	COG1024	Enoyl-CoA hydratase
K7I03_RS05065	COG0596	Alpha beta hydrolase
K7I03_RS05090	COG2936	dipeptidyl-peptidase activity
K7I03_RS05095	COG2936	dipeptidyl-peptidase activity
K7I03_RS05105	COG0789	Transcriptional regulator
K7I03_RS05120	COG1250	3-hydroxyacyl-CoA dehydrogenase
K7I03_RS05120	COG1024	Enoyl-CoA hydratase
K7I03_RS05125	COG0183	Belongs to the thiolase family
K7I03_RS05130	COG1960	acyl-CoA dehydrogenase activity
K7I03_RS05135	COG1804	L-carnitine dehydratase bile acid-inducible protein F
K7I03_RS05145	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
K7I03_RS05150	COG1515	deoxyribonuclease V activity
K7I03_RS05165	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
K7I03_RS05225	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
K7I03_RS05230	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
K7I03_RS05240	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
K7I03_RS05240	COG0825	malonyl-CoA metabolic process
K7I03_RS05245	COG0778	Nitroreductase
K7I03_RS05270	COG0179	Fumarylacetoacetate (FAA) hydrolase
K7I03_RS05325	COG2850	peptidyl-arginine hydroxylation
K7I03_RS05345	COG1012	belongs to the aldehyde dehydrogenase family
K7I03_RS05350	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
K7I03_RS05360	COG1846	Transcriptional regulator
K7I03_RS05385	COG2154	pterin-4-alpha-carbinolamine dehydratase
K7I03_RS05400	COG2197	response regulator
K7I03_RS05410	COG0531	amino acid
K7I03_RS05425	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K7I03_RS05485	COG1819	glycosyl
K7I03_RS05500	COG2132	Multicopper oxidase
K7I03_RS05580	COG0542	response to heat
K7I03_RS05640	COG2197	response regulator
K7I03_RS05670	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K7I03_RS05675	COG1535	isochorismatase
K7I03_RS05675	COG3433	isochorismatase activity
K7I03_RS05680	COG1021	2,3-dihydroxybenzoate-AMP ligase
K7I03_RS05685	COG1169	isochorismate synthase
K7I03_RS05690	COG1028	Short-chain dehydrogenase reductase Sdr
K7I03_RS05700	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K7I03_RS05730	COG1518	maintenance of DNA repeat elements
K7I03_RS05740	COG0667	Aldo Keto reductase
K7I03_RS05750	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
K7I03_RS05760	COG1028	Short-chain dehydrogenase reductase Sdr
K7I03_RS05865	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K7I03_RS05885	COG0596	Alpha beta hydrolase
K7I03_RS05890	COG2207	Transcriptional regulator
K7I03_RS05895	COG0604	alcohol dehydrogenase
K7I03_RS05910	COG0604	alcohol dehydrogenase
K7I03_RS05915	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
K7I03_RS05915	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
K7I03_RS05920	COG2301	Belongs to the HpcH HpaI aldolase family
K7I03_RS05930	COG1960	acyl-CoA dehydrogenase activity
K7I03_RS05935	COG0688	phosphatidylethanolamine metabolic process
K7I03_RS05945	COG3547	Transposase (IS116 IS110 IS902 family)
K7I03_RS05950	COG1929	Belongs to the glycerate kinase type-1 family
K7I03_RS05955	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
K7I03_RS05970	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
K7I03_RS05980	COG2815	serine threonine protein kinase
K7I03_RS05980	COG0515	serine threonine protein kinase
K7I03_RS06000	COG0542	response to heat
K7I03_RS06015	COG0483	inositol monophosphate 1-phosphatase activity
K7I03_RS06020	COG0095	Lipoate-protein ligase
K7I03_RS06065	COG2910	NAD(P)H-binding
K7I03_RS06080	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
K7I03_RS06085	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
K7I03_RS06095	COG1335	isochorismatase
K7I03_RS06100	COG0405	Gamma-glutamyltransferase
K7I03_RS06105	COG2755	lipolytic protein G-D-S-L family
K7I03_RS06110	COG1959	2 iron, 2 sulfur cluster binding
K7I03_RS06120	COG0765	amino acid transport
K7I03_RS06125	COG0765	amino acid transport
K7I03_RS06130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K7I03_RS06135	COG1126	abc transporter atp-binding protein
K7I03_RS06165	COG1846	Transcriptional regulator
K7I03_RS06175	COG0708	Exodeoxyribonuclease III
K7I03_RS06180	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
K7I03_RS06205	COG0745	RESPONSE REGULATOR receiver
K7I03_RS06270	COG1024	Enoyl-CoA hydratase
K7I03_RS06285	COG1024	Enoyl-CoA hydratase
K7I03_RS06290	COG1024	Enoyl-CoA hydratase
K7I03_RS06300	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K7I03_RS06315	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K7I03_RS06330	COG1960	acyl-CoA dehydrogenase activity
K7I03_RS06340	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
K7I03_RS06360	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
K7I03_RS06370	COG0443	Heat shock 70 kDa protein
K7I03_RS06390	COG1940	carbohydrate kinase activity
K7I03_RS06410	COG2188	Transcriptional regulator
K7I03_RS06445	COG4266	Belongs to the allantoicase family
K7I03_RS06450	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
K7I03_RS06455	COG1414	Transcriptional regulator
K7I03_RS06470	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
K7I03_RS06480	COG1132	(ABC) transporter
K7I03_RS06490	COG2233	PERMEase
K7I03_RS06505	COG2351	hydroxyisourate hydrolase activity
K7I03_RS06510	COG0583	DNA-binding transcription factor activity
K7I03_RS06520	COG0667	Aldo Keto reductase
K7I03_RS06530	COG2205	protein histidine kinase activity
K7I03_RS06535	COG0745	RESPONSE REGULATOR receiver
K7I03_RS06540	COG0438	transferase activity, transferring glycosyl groups
K7I03_RS06585	COG0300	oxidoreductase activity
K7I03_RS06630	COG3622	Belongs to the hyi family
K7I03_RS06635	COG2084	Dehydrogenase
K7I03_RS06640	COG3960	tartronate-semialdehyde synthase activity
K7I03_RS06655	COG0583	DNA-binding transcription factor activity
K7I03_RS06660	COG2130	NADP-dependent
K7I03_RS06665	COG0318	PFAM AMP-dependent synthetase and ligase
K7I03_RS06670	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K7I03_RS06710	COG1285	pathogenesis
K7I03_RS06725	COG3540	Alkaline phosphatase
K7I03_RS06735	COG0477	Major facilitator Superfamily
K7I03_RS06745	COG1028	Short-chain dehydrogenase reductase Sdr
K7I03_RS06750	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
K7I03_RS06755	COG1028	Short-chain dehydrogenase reductase Sdr
K7I03_RS06765	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
K7I03_RS06770	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
K7I03_RS06775	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
K7I03_RS06780	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K7I03_RS06785	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
K7I03_RS06795	COG0477	Major facilitator Superfamily
K7I03_RS06820	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
K7I03_RS06840	COG2252	PERMEase
K7I03_RS06845	COG1529	Aldehyde oxidase and xanthine dehydrogenase
K7I03_RS06860	COG3835	regulator
K7I03_RS06865	COG2964	Protein conserved in bacteria
K7I03_RS06870	COG0133	tryptophan synthase activity
K7I03_RS06910	COG1802	Transcriptional regulator
K7I03_RS06940	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
K7I03_RS06975	COG0175	sulfate reduction
K7I03_RS06980	COG0529	Catalyzes the synthesis of activated sulfate
K7I03_RS07000	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
K7I03_RS07005	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K7I03_RS07025	COG1280	lysine exporter protein (LysE YggA)
K7I03_RS07075	COG0583	DNA-binding transcription factor activity
K7I03_RS07080	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K7I03_RS07090	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
K7I03_RS07095	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
K7I03_RS07165	COG1278	Cold shock
K7I03_RS07185	COG2826	transposase and inactivated derivatives, IS30 family
K7I03_RS07215	COG0596	Alpha beta hydrolase
K7I03_RS07240	COG3253	May function as heme-dependent peroxidase
K7I03_RS07250	COG0183	Belongs to the thiolase family
K7I03_RS07260	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
K7I03_RS07280	COG0183	Belongs to the thiolase family
K7I03_RS07285	COG1024	Enoyl-CoA hydratase
K7I03_RS07285	COG1250	3-hydroxyacyl-CoA dehydrogenase
K7I03_RS07310	COG0531	amino acid
K7I03_RS07315	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
K7I03_RS07320	COG4214	carbohydrate transport
K7I03_RS07330	COG4213	ABC transporter substrate-binding protein
K7I03_RS07345	COG0395	ABC-type sugar transport system, permease component
K7I03_RS07350	COG1175	transmembrane transport
K7I03_RS07355	COG1653	transport
K7I03_RS07390	COG1309	transcriptional regulator
K7I03_RS07405	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
K7I03_RS07430	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
K7I03_RS07440	COG1917	Cupin 2, conserved barrel domain protein
K7I03_RS07455	COG1960	acyl-CoA dehydrogenase activity
K7I03_RS07475	COG1024	Enoyl-CoA hydratase
K7I03_RS07480	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
K7I03_RS07495	COG4977	sequence-specific DNA binding
K7I03_RS07500	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
K7I03_RS07510	COG2040	homocysteine
K7I03_RS07540	COG1799	cell septum assembly
K7I03_RS07555	COG1396	sequence-specific DNA binding
K7I03_RS07610	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
K7I03_RS07620	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
K7I03_RS07625	COG0531	amino acid
K7I03_RS07635	COG2124	cytochrome p450
K7I03_RS07660	COG0655	NAD(P)H dehydrogenase (quinone) activity
K7I03_RS07665	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
K7I03_RS07680	COG0569	domain protein
K7I03_RS07715	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
K7I03_RS07720	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
K7I03_RS07725	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
K7I03_RS07740	COG0756	dUTP diphosphatase activity
K7I03_RS07765	COG2205	protein histidine kinase activity
K7I03_RS07770	COG0745	RESPONSE REGULATOR receiver
K7I03_RS07785	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
K7I03_RS07820	COG1435	thymidine kinase activity
K7I03_RS07835	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K7I03_RS07835	COG1042	CoA-binding domain protein
K7I03_RS07835	COG0045	succinate-CoA ligase (ADP-forming) activity
K7I03_RS07840	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
K7I03_RS07845	COG1802	Transcriptional regulator
K7I03_RS07860	COG0612	Peptidase, M16
K7I03_RS07865	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
K7I03_RS07885	COG2197	response regulator
K7I03_RS07890	COG4585	Histidine kinase
K7I03_RS07900	COG0187	DNA topoisomerase II activity
K7I03_RS07915	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
K7I03_RS07920	COG2186	Transcriptional regulator
K7I03_RS07925	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
K7I03_RS07960	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
K7I03_RS07970	COG0588	phosphoglycerate mutase activity
K7I03_RS07975	COG0488	(ABC) transporter
K7I03_RS08000	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
K7I03_RS08005	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
K7I03_RS08010	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
K7I03_RS08035	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
K7I03_RS08045	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
K7I03_RS08050	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
K7I03_RS08060	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
K7I03_RS08080	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
K7I03_RS08090	COG2205	protein histidine kinase activity
K7I03_RS08100	COG1126	abc transporter atp-binding protein
K7I03_RS08105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K7I03_RS08110	COG0765	amino acid transport
K7I03_RS08115	COG0765	amino acid transport
K7I03_RS08120	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
K7I03_RS08135	COG2137	regulation of response to DNA damage stimulus
K7I03_RS08140	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
K7I03_RS08160	COG1201	RNA secondary structure unwinding
K7I03_RS08190	COG1396	sequence-specific DNA binding
K7I03_RS08195	COG1546	Belongs to the CinA family
K7I03_RS08195	COG1058	Belongs to the CinA family
K7I03_RS08205	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
K7I03_RS08215	COG1674	ftsk spoiiie
K7I03_RS08225	COG4999	Histidine kinase
K7I03_RS08225	COG3850	Histidine kinase
K7I03_RS08225	COG3437	response regulator, receiver
K7I03_RS08225	COG2205	protein histidine kinase activity
K7I03_RS08230	COG2208	phosphoserine phosphatase activity
K7I03_RS08230	COG2770	Histidine kinase
K7I03_RS08240	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
K7I03_RS08260	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
K7I03_RS08265	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
K7I03_RS08280	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
K7I03_RS08285	COG0612	Peptidase, M16
K7I03_RS08290	COG1185	polyribonucleotide nucleotidyltransferase activity
K7I03_RS08295	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
K7I03_RS08305	COG1674	ftsk spoiiie
K7I03_RS08340	COG1404	Belongs to the peptidase S8 family
K7I03_RS08365	COG1404	Belongs to the peptidase S8 family
K7I03_RS08390	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
K7I03_RS08390	COG0515	serine threonine protein kinase
K7I03_RS08415	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
K7I03_RS08420	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
K7I03_RS08430	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
K7I03_RS08445	COG0779	Required for maturation of 30S ribosomal subunits
K7I03_RS08465	COG0442	prolyl-tRNA aminoacylation
K7I03_RS08480	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
K7I03_RS08485	COG0750	zinc metalloprotease
K7I03_RS08490	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
K7I03_RS08500	COG2197	response regulator
K7I03_RS08505	COG4585	Histidine kinase
K7I03_RS08515	COG2508	Transcriptional regulator
K7I03_RS08540	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K7I03_RS08550	COG1176	ABC-type spermidine putrescine transport system, permease component I
K7I03_RS08555	COG3842	ATPase activity
K7I03_RS08570	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
K7I03_RS08590	COG1012	belongs to the aldehyde dehydrogenase family
K7I03_RS08600	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
K7I03_RS08620	COG3842	ATPase activity
K7I03_RS08640	COG0820	rRNA (adenine-C2-)-methyltransferase activity
K7I03_RS08650	COG0233	cytoplasmic translational termination
K7I03_RS08655	COG0528	UMP kinase activity
K7I03_RS08660	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
K7I03_RS08665	COG0052	Belongs to the universal ribosomal protein uS2 family
K7I03_RS08680	COG1191	sigma factor activity
K7I03_RS08695	COG0792	nuclease activity
K7I03_RS08710	COG0681	Belongs to the peptidase S26 family
K7I03_RS08715	COG0681	Belongs to the peptidase S26 family
K7I03_RS08725	COG0681	Belongs to the peptidase S26 family
K7I03_RS08730	COG0335	large ribosomal subunit rRNA binding
K7I03_RS08735	COG0336	Belongs to the RNA methyltransferase TrmD family
K7I03_RS08740	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
K7I03_RS08745	COG1837	Belongs to the UPF0109 family
K7I03_RS08750	COG0228	four-way junction DNA binding
K7I03_RS08760	COG0442	prolyl-tRNA aminoacylation
K7I03_RS08765	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
K7I03_RS08775	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
K7I03_RS08805	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
K7I03_RS08820	COG0546	phosphoglycolate phosphatase activity
K7I03_RS08835	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
K7I03_RS08840	COG3321	synthase
K7I03_RS08840	COG1028	Short-chain dehydrogenase reductase Sdr
K7I03_RS08840	COG0604	alcohol dehydrogenase
K7I03_RS08845	COG0583	DNA-binding transcription factor activity
K7I03_RS08890	COG0477	Major facilitator Superfamily
K7I03_RS08905	COG1254	Belongs to the acylphosphatase family
K7I03_RS08920	COG1733	regulation of RNA biosynthetic process
K7I03_RS08925	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
K7I03_RS08930	COG0571	ribonuclease III activity
K7I03_RS08935	COG0333	Belongs to the bacterial ribosomal protein bL32 family
K7I03_RS08950	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
K7I03_RS08955	COG0742	ribosomal rna small subunit methyltransferase
K7I03_RS08970	COG1461	Dihydroxyacetone kinase
K7I03_RS08975	COG0227	Belongs to the bacterial ribosomal protein bL28 family
K7I03_RS08980	COG0351	phosphomethylpyrimidine kinase
K7I03_RS09000	COG1181	Belongs to the D-alanine--D-alanine ligase family
K7I03_RS09005	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
K7I03_RS09015	COG1920	GTP binding
K7I03_RS09025	COG0776	regulation of translation
K7I03_RS09035	COG0066	3-isopropylmalate dehydratase activity
K7I03_RS09040	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
K7I03_RS09045	COG1414	Transcriptional regulator
K7I03_RS09090	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
K7I03_RS09095	COG0179	Fumarylacetoacetate (FAA) hydrolase
K7I03_RS09115	COG2018	Roadblock/LC7 domain
K7I03_RS09135	COG2018	Roadblock/LC7 domain
K7I03_RS09165	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
K7I03_RS09170	COG5492	domain, Protein
K7I03_RS09175	COG2353	YceI-like domain
K7I03_RS09180	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
K7I03_RS09195	COG0535	radical SAM domain protein
K7I03_RS09205	COG1132	(ABC) transporter
K7I03_RS09210	COG0477	Major facilitator Superfamily
K7I03_RS09215	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
K7I03_RS09220	COG0473	3-isopropylmalate dehydrogenase activity
K7I03_RS09255	COG1012	belongs to the aldehyde dehydrogenase family
K7I03_RS09260	COG0506	proline dehydrogenase activity
K7I03_RS09265	COG3835	regulator
K7I03_RS09295	COG2124	cytochrome p450
K7I03_RS09310	COG0477	Major facilitator Superfamily
K7I03_RS09315	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
K7I03_RS09320	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
K7I03_RS09325	COG0440	acetolactate synthase activity
K7I03_RS09345	COG0667	Aldo Keto reductase
K7I03_RS09350	COG0789	Transcriptional regulator
K7I03_RS09370	COG1672	PFAM Archaeal ATPase
K7I03_RS09370	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
K7I03_RS09385	COG0504	CTP synthase activity
K7I03_RS09390	COG2409	Drug exporters of the RND superfamily
K7I03_RS09400	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
K7I03_RS09410	COG0154	amidase activity
K7I03_RS09415	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
K7I03_RS09425	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
K7I03_RS09440	COG2197	response regulator
K7I03_RS09445	COG4585	Histidine kinase
K7I03_RS09520	COG0482	sulfurtransferase activity
K7I03_RS09540	COG2860	membrane
K7I03_RS09545	COG4608	Belongs to the ABC transporter superfamily
K7I03_RS09550	COG0444	Belongs to the ABC transporter superfamily
K7I03_RS09560	COG4166	transmembrane transport
K7I03_RS09590	COG0404	The glycine cleavage system catalyzes the degradation of glycine
K7I03_RS09595	COG0509	glycine decarboxylation via glycine cleavage system
K7I03_RS09600	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
K7I03_RS09605	COG1760	l-serine dehydratase
K7I03_RS09680	COG1376	ErfK ybiS ycfS ynhG family protein
K7I03_RS09690	COG1132	(ABC) transporter
K7I03_RS09695	COG1132	(ABC) transporter
K7I03_RS09715	COG0058	SHG alpha-glucan phosphorylase activity
K7I03_RS09725	COG0366	Alpha amylase catalytic
K7I03_RS09730	COG0366	Alpha amylase catalytic
K7I03_RS09735	COG3281	Trehalose synthase
K7I03_RS09740	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
K7I03_RS09790	COG1051	belongs to the nudix hydrolase family
K7I03_RS09795	COG0477	Major facilitator Superfamily
K7I03_RS09805	COG1301	dicarboxylic acid transport
K7I03_RS09810	COG3290	protein histidine kinase activity
K7I03_RS09815	COG4565	transcriptional regulatory protein
K7I03_RS09825	COG1175	transmembrane transport
K7I03_RS09830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K7I03_RS09860	COG0395	ABC-type sugar transport system, permease component
K7I03_RS09865	COG1136	(ABC) transporter
K7I03_RS09870	COG1136	(ABC) transporter
K7I03_RS09870	COG0577	efflux transmembrane transporter activity
K7I03_RS09875	COG2084	Dehydrogenase
K7I03_RS09880	COG0205	6-phosphofructokinase activity
K7I03_RS09885	COG0280	phosphate acetyltransferase
K7I03_RS09885	COG0857	belongs to the CobB CobQ family
K7I03_RS09890	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
K7I03_RS09930	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
K7I03_RS09930	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
K7I03_RS09980	COG0183	Belongs to the thiolase family
K7I03_RS10040	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
K7I03_RS10055	COG1250	3-hydroxyacyl-CoA dehydrogenase
K7I03_RS10075	COG2197	response regulator
K7I03_RS10090	COG0355	proton-transporting ATP synthase activity, rotational mechanism
K7I03_RS10095	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
K7I03_RS10100	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
K7I03_RS10105	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
K7I03_RS10110	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
K7I03_RS10115	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
K7I03_RS10120	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
K7I03_RS10135	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
K7I03_RS10140	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
K7I03_RS10145	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
K7I03_RS10155	COG2890	protein-(glutamine-N5) methyltransferase activity
K7I03_RS10160	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
K7I03_RS10165	COG0254	rRNA binding
K7I03_RS10180	COG0083	homoserine kinase activity
K7I03_RS10185	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
K7I03_RS10190	COG0460	homoserine dehydrogenase
K7I03_RS10195	COG0019	diaminopimelate decarboxylase activity
K7I03_RS10200	COG0018	arginyl-trna synthetase
K7I03_RS10200	COG0018	arginyl-trna synthetase
K7I03_RS10205	COG0745	RESPONSE REGULATOR receiver
K7I03_RS10230	COG0768	penicillin binding
K7I03_RS10320	COG1280	lysine exporter protein (LysE YggA)
K7I03_RS10335	COG2188	Transcriptional regulator
K7I03_RS10360	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
K7I03_RS10365	COG3708	Transcriptional regulator
K7I03_RS10365	COG2207	Transcriptional regulator
K7I03_RS10385	COG0745	RESPONSE REGULATOR receiver
K7I03_RS10390	COG2205	protein histidine kinase activity
K7I03_RS10395	COG0508	dehydrogenase complex catalyzes the overall conversion of
K7I03_RS10395	COG0567	Dehydrogenase, E1 component
K7I03_RS10475	COG0604	alcohol dehydrogenase
K7I03_RS10480	COG0281	malic enzyme
K7I03_RS10490	COG0765	amino acid transport
K7I03_RS10495	COG1126	abc transporter atp-binding protein
K7I03_RS10525	COG0583	DNA-binding transcription factor activity
K7I03_RS10535	COG0697	spore germination
K7I03_RS10540	COG1846	Transcriptional regulator
K7I03_RS10555	COG0640	Transcriptional regulator
K7I03_RS10570	COG1316	TRANSCRIPTIONal
K7I03_RS10585	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
K7I03_RS10605	COG2066	Belongs to the glutaminase family
K7I03_RS10650	COG1597	lipid kinase activity
K7I03_RS10665	COG1309	transcriptional regulator
K7I03_RS10670	COG1028	Short-chain dehydrogenase reductase Sdr
K7I03_RS10675	COG0363	glucosamine-6-phosphate deaminase activity
K7I03_RS10680	COG1472	Belongs to the glycosyl hydrolase 3 family
K7I03_RS10685	COG0395	ABC-type sugar transport system, permease component
K7I03_RS10690	COG1175	transmembrane transport
K7I03_RS10695	COG2182	Extracellular solute-binding protein
K7I03_RS10700	COG2188	Transcriptional regulator
K7I03_RS10715	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
K7I03_RS10730	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
K7I03_RS10740	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
K7I03_RS10750	COG0242	peptide deformylase activity
K7I03_RS10765	COG5662	AntiSigma factor
K7I03_RS10770	COG1595	DNA-templated transcription, initiation
K7I03_RS10780	COG2135	peptidase activity
K7I03_RS10790	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
K7I03_RS10795	COG1162	GTPase activity
K7I03_RS10800	COG2076	Multidrug Resistance protein
K7I03_RS10810	COG0483	inositol monophosphate 1-phosphatase activity
K7I03_RS10820	COG0753	catalase activity
K7I03_RS10845	COG1615	UPF0182 protein
K7I03_RS10855	COG3480	Lon protease (S16) C-terminal proteolytic domain
K7I03_RS10890	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
K7I03_RS10930	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K7I03_RS10935	COG0210	DNA helicase
K7I03_RS10940	COG0210	DNA helicase
K7I03_RS10975	COG3842	ATPase activity
K7I03_RS10980	COG0596	Alpha beta hydrolase
K7I03_RS11000	COG0640	Transcriptional regulator
K7I03_RS11005	COG1609	Transcriptional regulator
K7I03_RS11050	COG4172	Belongs to the ABC transporter superfamily
K7I03_RS11060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K7I03_RS11065	COG0747	negative chemotaxis
K7I03_RS11105	COG0513	Belongs to the DEAD box helicase family
K7I03_RS11110	COG1028	Short-chain dehydrogenase reductase Sdr
K7I03_RS11115	COG0596	Alpha beta hydrolase
K7I03_RS11125	COG1432	Conserved Protein
K7I03_RS11135	COG2095	MarC family integral membrane protein
K7I03_RS11155	COG0598	Magnesium transport protein CorA
K7I03_RS11195	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
K7I03_RS11200	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
K7I03_RS11210	COG1595	DNA-templated transcription, initiation
K7I03_RS11225	COG1024	Enoyl-CoA hydratase
K7I03_RS11230	COG0519	Catalyzes the synthesis of GMP from XMP
K7I03_RS11240	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
K7I03_RS11250	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K7I03_RS11285	COG2197	response regulator
K7I03_RS11290	COG4585	Histidine kinase
K7I03_RS11300	COG1131	(ABC) transporter
K7I03_RS11315	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
K7I03_RS11330	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K7I03_RS11335	COG0747	negative chemotaxis
K7I03_RS11345	COG0444	Belongs to the ABC transporter superfamily
K7I03_RS11350	COG4608	Belongs to the ABC transporter superfamily
K7I03_RS11360	COG1595	DNA-templated transcription, initiation
K7I03_RS11365	COG4608	Belongs to the ABC transporter superfamily
K7I03_RS11375	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K7I03_RS11380	COG0601	transmembrane transport
K7I03_RS11385	COG4166	transmembrane transport
K7I03_RS11410	COG4608	Belongs to the ABC transporter superfamily
K7I03_RS11420	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K7I03_RS11425	COG0601	transmembrane transport
K7I03_RS11435	COG1217	gtp-binding protein TYPA
K7I03_RS11485	COG0531	amino acid
K7I03_RS11515	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
K7I03_RS11545	COG0012	GTP binding
K7I03_RS11560	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
K7I03_RS11570	COG1570	exodeoxyribonuclease VII activity
K7I03_RS11575	COG1722	exodeoxyribonuclease VII activity
K7I03_RS11580	COG0778	Nitroreductase
K7I03_RS11605	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
K7I03_RS11605	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
K7I03_RS11615	COG0114	fumarate hydratase activity
K7I03_RS11640	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K7I03_RS11660	COG1136	(ABC) transporter
K7I03_RS11680	COG0450	alkyl hydroperoxide reductase
K7I03_RS11685	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
K7I03_RS11700	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
K7I03_RS11705	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
K7I03_RS11710	COG0667	Aldo Keto reductase
K7I03_RS11735	COG2885	chlorophyll binding
K7I03_RS11815	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
K7I03_RS11830	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
K7I03_RS11840	COG0477	Major facilitator Superfamily
K7I03_RS11850	COG1331	Highly conserved protein containing a thioredoxin domain
K7I03_RS11855	COG2255	four-way junction helicase activity
K7I03_RS11865	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
K7I03_RS11875	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
K7I03_RS11890	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
K7I03_RS11910	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
K7I03_RS11920	COG1819	glycosyl
K7I03_RS11950	COG0531	amino acid
K7I03_RS11965	COG1376	ErfK ybiS ycfS ynhG family protein
K7I03_RS11975	COG2986	histidine ammonia-lyase
K7I03_RS11985	COG1024	Enoyl-CoA hydratase
K7I03_RS11990	COG0328	RNA-DNA hybrid ribonuclease activity
K7I03_RS11995	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
K7I03_RS12005	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
K7I03_RS12015	COG0768	penicillin binding
K7I03_RS12020	COG0424	maF-like protein
K7I03_RS12030	COG4770	biotin carboxylase activity
K7I03_RS12070	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
K7I03_RS12120	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
K7I03_RS12125	COG1012	belongs to the aldehyde dehydrogenase family
K7I03_RS12130	COG1012	belongs to the aldehyde dehydrogenase family
K7I03_RS12145	COG1595	DNA-templated transcription, initiation
K7I03_RS12150	COG0745	RESPONSE REGULATOR receiver
K7I03_RS12155	COG2205	protein histidine kinase activity
K7I03_RS12180	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
K7I03_RS12190	COG0583	DNA-binding transcription factor activity
K7I03_RS12195	COG2814	Major facilitator Superfamily
K7I03_RS12210	COG1079	Belongs to the binding-protein-dependent transport system permease family
K7I03_RS12215	COG4603	Belongs to the binding-protein-dependent transport system permease family
K7I03_RS12220	COG3845	ABC transporter
K7I03_RS12225	COG1744	ABC transporter substrate-binding protein PnrA-like
K7I03_RS12230	COG1473	amidohydrolase
K7I03_RS12230	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
K7I03_RS12240	COG2089	acid synthase
K7I03_RS12255	COG1216	Glycosyl transferase, family 2
K7I03_RS12265	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
K7I03_RS12285	COG3265	gluconokinase activity
K7I03_RS12290	COG2186	Transcriptional regulator
K7I03_RS12330	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
K7I03_RS12330	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
K7I03_RS12340	COG1595	DNA-templated transcription, initiation
K7I03_RS12360	COG2009	succinate dehydrogenase
K7I03_RS12370	COG1053	succinate dehydrogenase
K7I03_RS12380	COG2826	transposase and inactivated derivatives, IS30 family
K7I03_RS12390	COG0667	Aldo Keto reductase
K7I03_RS12400	COG0747	negative chemotaxis
K7I03_RS12410	COG1686	Belongs to the peptidase S11 family
K7I03_RS12415	COG1295	ribonuclease BN
K7I03_RS12425	COG0180	Tryptophanyl-tRNA synthetase
K7I03_RS12430	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
K7I03_RS12435	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
K7I03_RS12470	COG0754	glutathionylspermidine amidase activity
K7I03_RS12480	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K7I03_RS12485	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
K7I03_RS12505	COG4176	ABC-type proline glycine betaine transport system permease component
K7I03_RS12510	COG0517	IMP dehydrogenase activity
K7I03_RS12510	COG4175	Glycine betaine
K7I03_RS12520	COG1012	belongs to the aldehyde dehydrogenase family
K7I03_RS12585	COG0039	L-malate dehydrogenase activity
K7I03_RS12610	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
K7I03_RS12620	COG0138	bifunctional purine biosynthesis protein purh
K7I03_RS12655	COG0045	succinate-CoA ligase (ADP-forming) activity
K7I03_RS12660	COG3552	Protein containing von Willebrand factor type A (VWA) domain
K7I03_RS12670	COG0714	Associated with various cellular activities
K7I03_RS12685	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
K7I03_RS12685	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
K7I03_RS12690	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
K7I03_RS12695	COG0739	heme binding
K7I03_RS12720	COG2197	response regulator
K7I03_RS12730	COG0515	serine threonine protein kinase
K7I03_RS12730	COG2815	serine threonine protein kinase
K7I03_RS12750	COG0519	Catalyzes the synthesis of GMP from XMP
K7I03_RS12750	COG0518	GMP synthase (glutamine-hydrolyzing) activity
K7I03_RS12765	COG1012	belongs to the aldehyde dehydrogenase family
K7I03_RS12770	COG0515	serine threonine protein kinase
K7I03_RS12770	COG2815	serine threonine protein kinase
K7I03_RS12805	COG1366	Belongs to the anti-sigma-factor antagonist family
K7I03_RS12845	COG1131	(ABC) transporter
K7I03_RS12860	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
K7I03_RS12865	COG2945	thiolester hydrolase activity
K7I03_RS12865	COG0596	Alpha beta hydrolase
K7I03_RS12875	COG4821	SIS domain
K7I03_RS12885	COG0259	pyridoxamine-phosphate oxidase activity
K7I03_RS12900	COG1024	Enoyl-CoA hydratase
K7I03_RS12915	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
K7I03_RS12950	COG3548	integral membrane protein
K7I03_RS12960	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
K7I03_RS12980	COG2814	Major facilitator Superfamily
K7I03_RS12990	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
K7I03_RS12995	COG2318	DinB family
K7I03_RS13000	COG1113	amino acid transport
K7I03_RS13010	COG2076	Multidrug Resistance protein
K7I03_RS13025	COG2890	protein-(glutamine-N5) methyltransferase activity
K7I03_RS13045	COG1595	DNA-templated transcription, initiation
K7I03_RS13050	COG0640	Transcriptional regulator
K7I03_RS13055	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
K7I03_RS13060	COG1215	transferase activity, transferring glycosyl groups
K7I03_RS13065	COG0667	Aldo Keto reductase
K7I03_RS13100	COG2252	PERMEase
K7I03_RS13110	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
K7I03_RS13125	COG0702	epimerase
K7I03_RS13160	COG2814	Major facilitator Superfamily
K7I03_RS13170	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
K7I03_RS13175	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
K7I03_RS13195	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K7I03_RS13200	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K7I03_RS13270	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
K7I03_RS13285	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
K7I03_RS13290	COG1061	Type III restriction enzyme res subunit
K7I03_RS13310	COG3973	AAA domain
K7I03_RS13325	COG2814	Major facilitator Superfamily
K7I03_RS13355	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
K7I03_RS13390	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K7I03_RS13390	COG1263	PTS System
K7I03_RS13400	COG1278	Cold shock
K7I03_RS13415	COG0463	Glycosyl transferase, family 2
K7I03_RS13420	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
K7I03_RS13445	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
K7I03_RS13450	COG1846	Transcriptional regulator
K7I03_RS13450	COG1940	carbohydrate kinase activity
K7I03_RS13460	COG1105	Belongs to the carbohydrate kinase PfkB family
K7I03_RS13520	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
K7I03_RS13535	COG4941	Belongs to the sigma-70 factor family
K7I03_RS13545	COG4585	Histidine kinase
K7I03_RS13550	COG2409	Drug exporters of the RND superfamily
K7I03_RS13590	COG2409	Drug exporters of the RND superfamily
K7I03_RS13600	COG3842	ATPase activity
K7I03_RS13610	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
K7I03_RS13620	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
K7I03_RS13625	COG0215	cysteine-tRNA ligase activity
K7I03_RS13635	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
K7I03_RS13640	COG3467	pyridoxamine 5'-phosphate
K7I03_RS13645	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
K7I03_RS13650	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
K7I03_RS13655	COG1329	Transcriptional regulator
K7I03_RS13670	COG5002	protein histidine kinase activity
K7I03_RS13680	COG0588	phosphoglycerate mutase activity
K7I03_RS13695	COG0438	transferase activity, transferring glycosyl groups
K7I03_RS13705	COG0494	nUDIX hydrolase
K7I03_RS13705	COG0406	alpha-ribazole phosphatase activity
K7I03_RS13725	COG1131	(ABC) transporter
K7I03_RS13730	COG1725	Transcriptional regulator
K7I03_RS13735	COG0456	acetyltransferase
K7I03_RS13735	COG0454	-acetyltransferase
K7I03_RS13740	COG0737	Belongs to the 5'-nucleotidase family
K7I03_RS13760	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
K7I03_RS13770	COG1609	Transcriptional regulator
K7I03_RS13775	COG0745	RESPONSE REGULATOR receiver
K7I03_RS13810	COG2897	thiosulfate sulfurtransferase activity
K7I03_RS13830	COG3485	protocatechuate 3,4-dioxygenase
K7I03_RS13835	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K7I03_RS13840	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
K7I03_RS13860	COG1490	D-aminoacyl-tRNA deacylase activity
K7I03_RS13875	COG4552	Acetyltransferase involved in intracellular survival and related
K7I03_RS13880	COG0431	NADPH-dependent FMN reductase
K7I03_RS13885	COG1733	regulation of RNA biosynthetic process
K7I03_RS13905	COG0477	Major facilitator Superfamily
K7I03_RS13910	COG0583	DNA-binding transcription factor activity
K7I03_RS13935	COG0667	Aldo Keto reductase
K7I03_RS14000	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
K7I03_RS14015	COG1937	Protein conserved in bacteria
K7I03_RS14035	COG0277	FAD linked oxidase domain protein
K7I03_RS14045	COG0671	phosphoesterase, PA-phosphatase related
K7I03_RS14050	COG0791	NLP P60 protein
K7I03_RS14095	COG0515	serine threonine protein kinase
K7I03_RS14095	COG2815	serine threonine protein kinase
K7I03_RS14140	COG2197	response regulator
K7I03_RS14145	COG4585	Histidine kinase
K7I03_RS14150	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
K7I03_RS14190	COG0129	dihydroxy-acid dehydratase activity
K7I03_RS14200	COG1082	Xylose isomerase domain protein TIM barrel
K7I03_RS14205	COG0248	Ppx GppA phosphatase
K7I03_RS14225	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
K7I03_RS14250	COG1595	DNA-templated transcription, initiation
K7I03_RS14260	COG0745	RESPONSE REGULATOR receiver
K7I03_RS14265	COG2205	protein histidine kinase activity
K7I03_RS14275	COG1196	nuclear chromosome segregation
K7I03_RS14275	COG0741	lytic transglycosylase activity
K7I03_RS14275	COG0739	heme binding
K7I03_RS14305	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
K7I03_RS14325	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
K7I03_RS14335	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
K7I03_RS14340	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
K7I03_RS14360	COG0583	DNA-binding transcription factor activity
K7I03_RS14385	COG0649	NAD binding
K7I03_RS14400	COG1174	glycine betaine transport
K7I03_RS14405	COG1174	glycine betaine transport
K7I03_RS14420	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
K7I03_RS14425	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
K7I03_RS14440	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
K7I03_RS14440	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
K7I03_RS14450	COG0302	gtp cyclohydrolase
K7I03_RS14465	COG0037	tRNA processing
K7I03_RS14475	COG2027	D-alanyl-D-alanine carboxypeptidase
K7I03_RS14480	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
K7I03_RS14490	COG0586	Pfam SNARE associated Golgi protein
K7I03_RS14495	COG0393	Putative heavy-metal-binding
K7I03_RS14515	COG2318	DinB family
K7I03_RS14520	COG1012	belongs to the aldehyde dehydrogenase family
K7I03_RS14550	COG1077	Cell shape determining protein MreB Mrl
K7I03_RS14595	COG1595	DNA-templated transcription, initiation
K7I03_RS14650	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
K7I03_RS14660	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
K7I03_RS14675	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
K7I03_RS14700	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
K7I03_RS14705	COG0386	Belongs to the glutathione peroxidase family
K7I03_RS14720	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
K7I03_RS14735	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
K7I03_RS14765	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
K7I03_RS14770	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
K7I03_RS14785	COG0477	Major facilitator Superfamily
K7I03_RS14790	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
K7I03_RS14810	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K7I03_RS14850	COG0475	glutathione-regulated potassium exporter activity
K7I03_RS14900	COG2226	methyltransferase
K7I03_RS14915	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
K7I03_RS14935	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
K7I03_RS15010	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
K7I03_RS15015	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
K7I03_RS15020	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
K7I03_RS15020	COG1754	DNA topoisomerase type I activity
K7I03_RS15040	COG2890	protein-(glutamine-N5) methyltransferase activity
K7I03_RS15050	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
K7I03_RS15055	COG2172	sigma factor antagonist activity
K7I03_RS15060	COG1366	Belongs to the anti-sigma-factor antagonist family
K7I03_RS15065	COG1111	helicase
K7I03_RS15065	COG1205	dead DEAH box helicase
K7I03_RS15130	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K7I03_RS15135	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
K7I03_RS15145	COG2267	carboxylic ester hydrolase activity
K7I03_RS15175	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K7I03_RS15200	COG0003	Pfam Anion-transporting ATPase
K7I03_RS15210	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K7I03_RS15220	COG1408	metallophosphoesterase
K7I03_RS15235	COG3850	Histidine kinase
K7I03_RS15240	COG2197	response regulator
K7I03_RS15250	COG3479	Phenolic acid decarboxylase
K7I03_RS15275	COG1595	DNA-templated transcription, initiation
K7I03_RS15305	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
K7I03_RS15310	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
K7I03_RS15345	COG2770	Histidine kinase
K7I03_RS15345	COG2208	phosphoserine phosphatase activity
K7I03_RS15390	COG0789	Transcriptional regulator
K7I03_RS15420	COG0583	DNA-binding transcription factor activity
K7I03_RS15425	COG0596	Alpha beta hydrolase
K7I03_RS15430	COG1028	Short-chain dehydrogenase reductase Sdr
K7I03_RS15450	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
K7I03_RS15510	COG1191	sigma factor activity
K7I03_RS15515	COG1191	sigma factor activity
K7I03_RS15525	COG1846	Transcriptional regulator
K7I03_RS15540	COG0477	Major facilitator Superfamily
K7I03_RS15580	COG1309	transcriptional regulator
K7I03_RS15585	COG2814	Major facilitator Superfamily
K7I03_RS15590	COG0318	PFAM AMP-dependent synthetase and ligase
K7I03_RS15595	COG1595	DNA-templated transcription, initiation
K7I03_RS15635	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
K7I03_RS15650	COG0653	protein targeting
K7I03_RS15670	COG0006	proline dipeptidase activity
K7I03_RS15685	COG3795	YCII-related domain
K7I03_RS15690	COG4941	Belongs to the sigma-70 factor family
K7I03_RS15720	COG2372	response to copper ion
K7I03_RS15725	COG2837	iron assimilation
K7I03_RS15735	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
K7I03_RS15740	COG0561	phosphatase activity
K7I03_RS15780	COG2807	transmembrane transport
K7I03_RS15810	COG1215	transferase activity, transferring glycosyl groups
K7I03_RS15835	COG1131	(ABC) transporter
K7I03_RS15855	COG0789	Transcriptional regulator
K7I03_RS15865	COG0501	Belongs to the peptidase M48B family
K7I03_RS15885	COG0561	phosphatase activity
K7I03_RS15905	COG4988	ABC transporter
K7I03_RS15910	COG1294	oxidase, subunit
K7I03_RS15915	COG1271	oxidase subunit
K7I03_RS15920	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
K7I03_RS15925	COG1609	Transcriptional regulator
K7I03_RS15930	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
K7I03_RS15940	COG2304	oxidoreductase activity
K7I03_RS15965	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
K7I03_RS15980	COG2268	Band 7 protein
K7I03_RS15995	COG0662	Cupin 2, conserved barrel domain protein
K7I03_RS16000	COG1950	PFAM Membrane protein of
K7I03_RS16015	COG2816	NAD+ diphosphatase activity
K7I03_RS16040	COG2814	Major facilitator Superfamily
K7I03_RS16075	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
K7I03_RS16095	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
K7I03_RS16105	COG4978	Transcriptional regulator
K7I03_RS16105	COG0789	Transcriptional regulator
K7I03_RS16115	COG0697	spore germination
K7I03_RS16120	COG2910	NAD(P)H-binding
K7I03_RS16130	COG1309	transcriptional regulator
K7I03_RS16150	COG0305	Participates in initiation and elongation during chromosome replication
K7I03_RS16160	COG0359	binds to the 23S rRNA
K7I03_RS16165	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
K7I03_RS16170	COG0629	single-stranded DNA binding
K7I03_RS16175	COG0360	Binds together with S18 to 16S ribosomal RNA
K7I03_RS16200	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K7I03_RS16210	COG1260	myo-inositol-1-phosphate synthase
K7I03_RS16220	COG0617	tRNA 3'-terminal CCA addition
K7I03_RS16240	COG1595	DNA-templated transcription, initiation
K7I03_RS16250	COG0492	ferredoxin-NADP+ reductase activity
K7I03_RS16255	COG3118	belongs to the thioredoxin family
K7I03_RS16270	COG1192	Involved in chromosome partitioning
K7I03_RS16275	COG0357	Ribosomal RNA small subunit methyltransferase G
K7I03_RS16285	COG0706	membrane insertase activity
K7I03_RS16290	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
K7I03_RS16300	COG0230	Belongs to the bacterial ribosomal protein bL34 family
K7I03_RS16310	COG0592	DNA-directed DNA polymerase activity
K7I03_RS16315	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
K7I03_RS16320	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
K7I03_RS16325	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
K7I03_RS16330	COG0187	DNA topoisomerase II activity
K7I03_RS16335	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
K7I03_RS16340	COG3266	domain, Protein
K7I03_RS16355	COG0515	serine threonine protein kinase
K7I03_RS16380	COG0705	Rhomboid family
K7I03_RS16405	COG3764	Sortase (surface protein transpeptidase)
K7I03_RS16410	COG3764	Sortase (surface protein transpeptidase)
K7I03_RS16415	COG0515	serine threonine protein kinase
K7I03_RS16420	COG0768	penicillin binding
K7I03_RS16435	COG1716	ATPase activity
K7I03_RS16440	COG1716	ATPase activity
K7I03_RS16465	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
K7I03_RS16470	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
K7I03_RS16475	COG2151	metal-sulfur cluster biosynthetic enzyme
K7I03_RS16480	COG3396	Phenylacetate-CoA oxygenase
K7I03_RS16485	COG3460	Phenylacetate-CoA oxygenase
K7I03_RS16490	COG3396	Phenylacetate-CoA oxygenase
K7I03_RS16515	COG1250	3-hydroxyacyl-CoA dehydrogenase
K7I03_RS16520	COG1309	transcriptional regulator
K7I03_RS16525	COG1522	sequence-specific DNA binding
K7I03_RS16535	COG0022	dehydrogenase e1 component
K7I03_RS16585	COG0515	serine threonine protein kinase
K7I03_RS16590	COG0515	serine threonine protein kinase
K7I03_RS16615	COG0022	dehydrogenase e1 component
K7I03_RS16620	COG0508	dehydrogenase complex catalyzes the overall conversion of
K7I03_RS16700	COG1362	aminopeptidase activity
K7I03_RS16705	COG1960	acyl-CoA dehydrogenase activity
K7I03_RS16720	COG1741	Belongs to the pirin family
K7I03_RS16730	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
K7I03_RS16740	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K7I03_RS16830	COG1278	Cold shock
K7I03_RS16840	COG4585	Histidine kinase
K7I03_RS16845	COG2197	response regulator
K7I03_RS16850	COG3655	Transcriptional regulator
K7I03_RS16895	COG2188	Transcriptional regulator
K7I03_RS16925	COG2188	Transcriptional regulator
K7I03_RS17005	COG0717	Belongs to the dCTP deaminase family
K7I03_RS17035	COG0247	lactate metabolic process
K7I03_RS17035	COG2181	nitrate reductase activity
K7I03_RS17040	COG0443	Heat shock 70 kDa protein
K7I03_RS17045	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
K7I03_RS17050	COG0484	heat shock protein binding
K7I03_RS17055	COG0789	Transcriptional regulator
K7I03_RS17065	COG1028	Short-chain dehydrogenase reductase Sdr
K7I03_RS17070	COG0583	DNA-binding transcription factor activity
K7I03_RS17090	COG0542	response to heat
K7I03_RS17115	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
K7I03_RS17145	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
K7I03_RS17155	COG0477	Major facilitator Superfamily
K7I03_RS17165	COG3483	tryptophan 2,3-dioxygenase activity
K7I03_RS17170	COG3844	kynureninase activity
K7I03_RS17180	COG4585	Histidine kinase
K7I03_RS17185	COG2197	response regulator
K7I03_RS17195	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
K7I03_RS17205	COG1278	Cold shock
K7I03_RS17210	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
K7I03_RS17215	COG1802	Transcriptional regulator
K7I03_RS17220	COG0463	Glycosyl transferase, family 2
K7I03_RS17235	COG0151	Belongs to the GarS family
K7I03_RS17250	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
K7I03_RS17255	COG0745	RESPONSE REGULATOR receiver
K7I03_RS17270	COG2197	response regulator
K7I03_RS17305	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
K7I03_RS17310	COG0047	phosphoribosylformylglycinamidine synthase activity
K7I03_RS17315	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
K7I03_RS17340	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
K7I03_RS17375	COG1643	Atp-dependent helicase
K7I03_RS17405	COG0513	Belongs to the DEAD box helicase family
K7I03_RS17430	COG1278	Cold shock
K7I03_RS17435	COG0513	Belongs to the DEAD box helicase family
K7I03_RS17450	COG2271	Major facilitator Superfamily
K7I03_RS17455	COG0667	Aldo Keto reductase
K7I03_RS17505	COG0220	tRNA (guanine-N7-)-methyltransferase activity
K7I03_RS17510	COG0579	oxidoreductase
K7I03_RS17525	COG1470	cell adhesion involved in biofilm formation
K7I03_RS17525	COG0366	Alpha amylase catalytic
K7I03_RS17575	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
K7I03_RS17580	COG0180	Tryptophanyl-tRNA synthetase
K7I03_RS17600	COG0123	including yeast histone deacetylase and acetoin utilization protein
K7I03_RS17650	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
K7I03_RS17655	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
K7I03_RS17660	COG0181	hydroxymethylbilane synthase activity
K7I03_RS17665	COG1648	precorrin-2 dehydrogenase activity
K7I03_RS17665	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
K7I03_RS17670	COG0113	porphobilinogen synthase activity
K7I03_RS17680	COG0018	arginyl-trna synthetase
K7I03_RS17685	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
K7I03_RS17700	COG1690	Belongs to the RtcB family
K7I03_RS17725	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
K7I03_RS17730	COG0406	alpha-ribazole phosphatase activity
K7I03_RS17745	COG0785	Cytochrome C biogenesis protein
K7I03_RS17750	COG1333	cytochrome c biogenesis protein
K7I03_RS17755	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
K7I03_RS17780	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
K7I03_RS17795	COG0163	prenyltransferase activity
K7I03_RS17810	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
K7I03_RS17825	COG1301	dicarboxylic acid transport
K7I03_RS17860	COG1309	transcriptional regulator
K7I03_RS17880	COG1278	Cold shock
K7I03_RS17885	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
K7I03_RS17890	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
K7I03_RS17895	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
K7I03_RS17905	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
K7I03_RS17925	COG2226	methyltransferase
K7I03_RS17940	COG2226	methyltransferase
K7I03_RS17950	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
K7I03_RS17960	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
K7I03_RS17970	COG1073	alpha beta
K7I03_RS17985	COG0477	Major facilitator Superfamily
K7I03_RS18030	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K7I03_RS18035	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K7I03_RS18040	COG0649	NAD binding
K7I03_RS18050	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
K7I03_RS18055	COG1034	ATP synthesis coupled electron transport
K7I03_RS18060	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
K7I03_RS18065	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K7I03_RS18070	COG0839	Belongs to the complex I subunit 6 family
K7I03_RS18075	COG0713	ATP synthesis coupled electron transport
K7I03_RS18080	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
K7I03_RS18105	COG0492	ferredoxin-NADP+ reductase activity
K7I03_RS18110	COG0142	geranyltranstransferase activity
K7I03_RS18130	COG4935	Belongs to the peptidase S8 family
K7I03_RS18130	COG2234	aminopeptidase activity
K7I03_RS18140	COG0531	amino acid
K7I03_RS18145	COG1013	pyruvate-flavodoxin oxidoreductase activity
K7I03_RS18150	COG0674	pyruvate-flavodoxin oxidoreductase activity
K7I03_RS18150	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
K7I03_RS18170	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K7I03_RS18175	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K7I03_RS18180	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K7I03_RS18185	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
K7I03_RS18190	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K7I03_RS18195	COG0839	Belongs to the complex I subunit 6 family
K7I03_RS18200	COG0713	ATP synthesis coupled electron transport
K7I03_RS18205	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
K7I03_RS18215	COG1007	ATP synthesis coupled electron transport
K7I03_RS18220	COG0501	Belongs to the peptidase M48B family
K7I03_RS18240	COG0583	DNA-binding transcription factor activity
K7I03_RS18250	COG3304	Inner membrane component domain
K7I03_RS18265	COG1666	GTP binding
K7I03_RS18275	COG0702	epimerase
K7I03_RS18295	COG0267	Belongs to the bacterial ribosomal protein bL33 family
K7I03_RS18300	COG2030	dehydratase
K7I03_RS18320	COG0812	UDP-N-acetylmuramate dehydrogenase activity
K7I03_RS18325	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
K7I03_RS18330	COG0436	Aminotransferase
K7I03_RS18345	COG0250	Participates in transcription elongation, termination and antitermination
K7I03_RS18350	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
K7I03_RS18355	COG0081	regulation of translation
K7I03_RS18375	COG0222	ribosome binding
K7I03_RS18380	COG0085	RNA polymerase activity
K7I03_RS18385	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
K7I03_RS18515	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
K7I03_RS18520	COG0049	tRNA binding
K7I03_RS18525	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
K7I03_RS18550	COG0051	transcription antitermination factor activity, RNA binding
K7I03_RS18555	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
K7I03_RS18560	COG0088	Forms part of the polypeptide exit tunnel
K7I03_RS18565	COG0089	rRNA binding
K7I03_RS18570	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
K7I03_RS18575	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
K7I03_RS18580	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
K7I03_RS18585	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
K7I03_RS18590	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
K7I03_RS18595	COG0255	Belongs to the universal ribosomal protein uL29 family
K7I03_RS18600	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
K7I03_RS18605	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
K7I03_RS18610	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
K7I03_RS18615	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
K7I03_RS18620	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
K7I03_RS18625	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
K7I03_RS18630	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
K7I03_RS18635	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
K7I03_RS18640	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
K7I03_RS18645	COG1841	ribosomal large subunit assembly
K7I03_RS18650	COG0200	Binds to the 23S rRNA
K7I03_RS18660	COG0563	adenylate kinase activity
K7I03_RS18670	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
K7I03_RS18675	COG0257	Belongs to the bacterial ribosomal protein bL36 family
K7I03_RS18680	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
K7I03_RS18685	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
K7I03_RS18695	COG0203	ribosomal protein L17
K7I03_RS18700	COG0101	tRNA pseudouridine synthase activity
K7I03_RS18720	COG0488	(ABC) transporter
K7I03_RS18725	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
K7I03_RS18730	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
K7I03_RS18735	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
K7I03_RS18740	COG1072	(Pantothenic acid kinase))
K7I03_RS18750	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
K7I03_RS18755	COG0736	holo-[acyl-carrier-protein] synthase activity
K7I03_RS18785	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
K7I03_RS18795	COG0802	atpase or kinase
K7I03_RS18830	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
K7I03_RS18855	COG0726	polysaccharide deacetylase
K7I03_RS18870	COG4221	oxidoreductase activity
K7I03_RS18880	COG0583	DNA-binding transcription factor activity
K7I03_RS18890	COG2197	response regulator
K7I03_RS18895	COG1595	DNA-templated transcription, initiation
K7I03_RS18905	COG0516	GMP reductase activity
K7I03_RS18910	COG1077	Cell shape determining protein MreB Mrl
K7I03_RS18920	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
K7I03_RS18955	COG1309	transcriptional regulator
K7I03_RS18965	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
K7I03_RS18965	COG0515	serine threonine protein kinase
K7I03_RS19045	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
K7I03_RS19070	COG1686	Belongs to the peptidase S11 family
K7I03_RS19095	COG0514	ATP-dependent DNA helicase (RecQ)
K7I03_RS19110	COG2124	cytochrome p450
K7I03_RS19175	COG2188	Transcriptional regulator
K7I03_RS19215	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K7I03_RS19215	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K7I03_RS19230	COG4977	sequence-specific DNA binding
K7I03_RS19265	COG1846	Transcriptional regulator
K7I03_RS19270	COG3384	dioxygenase
K7I03_RS19295	COG0477	Major facilitator Superfamily
K7I03_RS19305	COG1349	DNA-binding transcription factor activity
K7I03_RS19335	COG1970	mechanosensitive ion channel activity
K7I03_RS19340	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
K7I03_RS19355	COG3263	regulation of cellular component size
K7I03_RS19365	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
K7I03_RS19370	COG1210	Utp--glucose-1-phosphate uridylyltransferase
K7I03_RS19380	COG0315	cyclic pyranopterin monophosphate synthase activity
K7I03_RS19385	COG0521	Mo-molybdopterin cofactor biosynthetic process
K7I03_RS19385	COG0315	cyclic pyranopterin monophosphate synthase activity
K7I03_RS19390	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K7I03_RS19440	COG0659	secondary active sulfate transmembrane transporter activity
K7I03_RS19465	COG2205	protein histidine kinase activity
K7I03_RS19470	COG0596	Alpha beta hydrolase
K7I03_RS19480	COG0708	Exodeoxyribonuclease III
K7I03_RS19490	COG2072	flavoprotein involved in K transport
K7I03_RS19505	COG0793	Belongs to the peptidase S41A family
K7I03_RS19505	COG4946	Tricorn protease homolog
K7I03_RS19515	COG2409	Drug exporters of the RND superfamily
K7I03_RS19535	COG1122	ATPase activity
K7I03_RS19575	COG0084	hydrolase, TatD family'
K7I03_RS19580	COG3584	3D domain protein
K7I03_RS19580	COG3583	domain protein
K7I03_RS19585	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
K7I03_RS19590	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
K7I03_RS19600	COG0488	(ABC) transporter
K7I03_RS19625	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
K7I03_RS19635	COG2197	response regulator
K7I03_RS19640	COG1846	Transcriptional regulator
K7I03_RS19645	COG4106	trans-aconitate 2-methyltransferase activity
K7I03_RS19655	COG1309	transcriptional regulator
K7I03_RS19665	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
K7I03_RS19670	COG0193	aminoacyl-tRNA hydrolase activity
K7I03_RS19675	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
K7I03_RS19680	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
K7I03_RS19685	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
K7I03_RS19700	COG4585	Histidine kinase
K7I03_RS19735	COG1136	(ABC) transporter
K7I03_RS19740	COG0577	efflux transmembrane transporter activity
K7I03_RS19790	COG2124	cytochrome p450
K7I03_RS19795	COG1652	LysM domain
K7I03_RS19805	COG0148	phosphopyruvate hydratase activity
K7I03_RS19825	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
K7I03_RS19845	COG1252	NADH dehydrogenase
K7I03_RS19850	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
K7I03_RS19855	COG0577	efflux transmembrane transporter activity
K7I03_RS19860	COG1136	(ABC) transporter
K7I03_RS19875	COG0179	Fumarylacetoacetate (FAA) hydrolase
K7I03_RS19885	COG0318	PFAM AMP-dependent synthetase and ligase
K7I03_RS19890	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
K7I03_RS19920	COG0604	alcohol dehydrogenase
K7I03_RS19945	COG0183	Belongs to the thiolase family
K7I03_RS19950	COG2755	lipolytic protein G-D-S-L family
K7I03_RS19965	COG0318	PFAM AMP-dependent synthetase and ligase
K7I03_RS19990	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
K7I03_RS20005	COG1228	amidohydrolase
K7I03_RS20015	COG1794	racemase activity, acting on amino acids and derivatives
K7I03_RS20020	COG1191	sigma factor activity
K7I03_RS20025	COG1366	Belongs to the anti-sigma-factor antagonist family
K7I03_RS20035	COG3104	oligopeptide transport
K7I03_RS20040	COG0745	RESPONSE REGULATOR receiver
K7I03_RS20045	COG2205	protein histidine kinase activity
K7I03_RS20070	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
K7I03_RS20130	COG1316	TRANSCRIPTIONal
K7I03_RS20135	COG1607	acyl-coa hydrolase
K7I03_RS20140	COG1316	TRANSCRIPTIONal
K7I03_RS20150	COG1316	TRANSCRIPTIONal
K7I03_RS20155	COG1316	TRANSCRIPTIONal
K7I03_RS20185	COG0778	Nitroreductase
K7I03_RS20185	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
K7I03_RS20190	COG0391	Required for morphogenesis under gluconeogenic growth conditions
K7I03_RS20225	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
K7I03_RS20240	COG1482	cell wall glycoprotein biosynthetic process
K7I03_RS20250	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
K7I03_RS20250	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
K7I03_RS20250	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
K7I03_RS20255	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
K7I03_RS20285	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
K7I03_RS20290	COG0745	RESPONSE REGULATOR receiver
K7I03_RS20295	COG5002	protein histidine kinase activity
K7I03_RS20300	COG0823	Involved in the tonB-independent uptake of proteins
K7I03_RS20310	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
K7I03_RS20315	COG2197	response regulator
K7I03_RS20330	COG0653	protein targeting
K7I03_RS20365	COG0463	Glycosyl transferase, family 2
K7I03_RS20380	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
K7I03_RS20390	COG1215	transferase activity, transferring glycosyl groups
K7I03_RS20400	COG0395	ABC-type sugar transport system, permease component
K7I03_RS20405	COG1175	transmembrane transport
K7I03_RS20410	COG1653	transport
K7I03_RS20425	COG0515	serine threonine protein kinase
K7I03_RS20430	COG0515	serine threonine protein kinase
K7I03_RS20435	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
K7I03_RS20450	COG2884	Cell division ATP-binding protein ftsE
K7I03_RS20455	COG2177	Part of the ABC transporter FtsEX involved in
K7I03_RS20460	COG0793	Belongs to the peptidase S41A family
K7I03_RS20465	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
K7I03_RS20485	COG0583	DNA-binding transcription factor activity
K7I03_RS20500	COG3973	AAA domain
K7I03_RS20510	COG0776	regulation of translation
K7I03_RS20515	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
K7I03_RS20520	COG1678	Uncharacterized ACR, COG1678
K7I03_RS20530	COG3525	Glycosyl hydrolase, family 20, catalytic domain
K7I03_RS20545	COG1529	Aldehyde oxidase and xanthine dehydrogenase
K7I03_RS20585	COG1404	Belongs to the peptidase S8 family
K7I03_RS20625	COG0583	DNA-binding transcription factor activity
K7I03_RS20635	COG2855	membrane
K7I03_RS20650	COG3654	unkown
K7I03_RS20675	COG3185	4-Hydroxyphenylpyruvate dioxygenase
K7I03_RS20680	COG0277	FAD linked oxidase domain protein
K7I03_RS20710	COG1335	isochorismatase
K7I03_RS20720	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
K7I03_RS20730	COG1113	amino acid transport
K7I03_RS20755	COG1234	tRNA 3'-trailer cleavage
K7I03_RS20760	COG1263	PTS System
K7I03_RS20765	COG1263	PTS System
K7I03_RS20770	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K7I03_RS20775	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
K7I03_RS20785	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
K7I03_RS20820	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
K7I03_RS20830	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K7I03_RS20865	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
K7I03_RS20880	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K7I03_RS20890	COG0706	membrane insertase activity
K7I03_RS20945	COG0673	inositol 2-dehydrogenase activity
K7I03_RS20950	COG1940	carbohydrate kinase activity
K7I03_RS20995	COG2186	Transcriptional regulator
K7I03_RS21015	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
K7I03_RS21015	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
K7I03_RS21035	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K7I03_RS21085	COG0406	alpha-ribazole phosphatase activity
K7I03_RS21110	COG0395	ABC-type sugar transport system, permease component
K7I03_RS21130	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
K7I03_RS21135	COG4977	sequence-specific DNA binding
K7I03_RS21145	COG0589	response to stress
K7I03_RS21150	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
K7I03_RS21165	COG1960	acyl-CoA dehydrogenase activity
K7I03_RS21180	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
K7I03_RS21185	COG1309	transcriptional regulator
K7I03_RS21195	COG1946	Acyl-CoA thioesterase
K7I03_RS21255	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
K7I03_RS21265	COG0583	DNA-binding transcription factor activity
K7I03_RS21275	COG1280	lysine exporter protein (LysE YggA)
K7I03_RS21285	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
K7I03_RS21305	COG0673	inositol 2-dehydrogenase activity
K7I03_RS21315	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
K7I03_RS21325	COG3718	enzyme involved in inositol metabolism
K7I03_RS21330	COG3962	Belongs to the TPP enzyme family
K7I03_RS21340	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
K7I03_RS21345	COG4566	intracellular signal transduction
K7I03_RS21365	COG3226	Transcriptional regulator
K7I03_RS21400	COG2814	Major facilitator Superfamily
K7I03_RS21405	COG2267	carboxylic ester hydrolase activity
K7I03_RS21440	COG1819	glycosyl
K7I03_RS21525	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
K7I03_RS21530	COG1053	succinate dehydrogenase
K7I03_RS21540	COG0583	DNA-binding transcription factor activity
K7I03_RS21545	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
K7I03_RS21550	COG1993	acr, cog1993
K7I03_RS21555	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
K7I03_RS21575	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
K7I03_RS21590	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
K7I03_RS21600	COG0477	Major facilitator Superfamily
K7I03_RS21605	COG1846	Transcriptional regulator
K7I03_RS21630	COG0629	single-stranded DNA binding
K7I03_RS21685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K7I03_RS21700	COG1486	melibiose metabolic process
K7I03_RS21715	COG1028	Short-chain dehydrogenase reductase Sdr
K7I03_RS21720	COG0668	transmembrane transport
K7I03_RS21740	COG2402	Toxic component of a toxin-antitoxin (TA) module. An RNase
K7I03_RS21820	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
K7I03_RS21830	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
K7I03_RS21835	COG1113	amino acid transport
K7I03_RS21840	COG1113	amino acid transport
K7I03_RS21855	COG1113	amino acid transport
K7I03_RS21880	COG3594	Acyltransferase
K7I03_RS21900	COG0544	peptidyl-prolyl cis-trans isomerase activity
K7I03_RS21905	COG0740	serine-type endopeptidase activity
K7I03_RS21910	COG0740	serine-type endopeptidase activity
K7I03_RS21915	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
K7I03_RS21945	COG0525	valine-tRNA ligase activity
K7I03_RS21955	COG1215	transferase activity, transferring glycosyl groups
K7I03_RS21970	COG2205	protein histidine kinase activity
K7I03_RS21975	COG0285	dihydrofolate synthase activity
K7I03_RS21985	COG0105	UTP biosynthetic process
K7I03_RS21990	COG1077	Cell shape determining protein MreB Mrl
K7I03_RS22005	COG0768	penicillin binding
K7I03_RS22010	COG0772	Belongs to the SEDS family
K7I03_RS22030	COG1530	ribonuclease E activity
K7I03_RS22035	COG0261	This protein binds to 23S rRNA in the presence of protein L20
K7I03_RS22040	COG0211	Belongs to the bacterial ribosomal protein bL27 family
K7I03_RS22045	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
K7I03_RS22055	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
K7I03_RS22065	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
K7I03_RS22080	COG0501	Belongs to the peptidase M48B family
K7I03_RS22095	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
K7I03_RS22105	COG0799	negative regulation of ribosome biogenesis
K7I03_RS22110	COG0588	phosphoglycerate mutase activity
K7I03_RS22125	COG0477	Major facilitator Superfamily
K7I03_RS22145	COG0495	leucyl-tRNA aminoacylation
K7I03_RS22155	COG1307	EDD domain protein, DegV family
K7I03_RS22180	COG0268	Binds directly to 16S ribosomal RNA
K7I03_RS22185	COG0481	GTPase activity
K7I03_RS22215	COG1420	regulation of RNA biosynthetic process
K7I03_RS22220	COG0484	heat shock protein binding
K7I03_RS22240	COG2249	NAD(P)H dehydrogenase (quinone) activity
K7I03_RS22245	COG0537	adenosine 5'-monophosphoramidase activity
K7I03_RS22250	COG1234	tRNA 3'-trailer cleavage
K7I03_RS22260	COG1486	melibiose metabolic process
K7I03_RS22275	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
K7I03_RS22315	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
K7I03_RS22345	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
K7I03_RS22355	COG1381	Involved in DNA repair and RecF pathway recombination
K7I03_RS22360	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
K7I03_RS22370	COG1108	ABC-type Mn2 Zn2 transport systems permease components
K7I03_RS22375	COG1121	(ABC) transporter
K7I03_RS22380	COG0803	Belongs to the bacterial solute-binding protein 9 family
K7I03_RS22380	COG3443	Belongs to the bacterial solute-binding protein 9 family
K7I03_RS22385	COG0423	glycine-tRNA ligase activity
K7I03_RS22430	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
K7I03_RS22430	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
K7I03_RS22490	COG2197	response regulator
K7I03_RS22525	COG0667	Aldo Keto reductase
K7I03_RS22530	COG0477	Major facilitator Superfamily
K7I03_RS22545	COG0574	Belongs to the PEP-utilizing enzyme family
K7I03_RS22545	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
K7I03_RS22555	COG0395	ABC-type sugar transport system, permease component
K7I03_RS22570	COG1215	transferase activity, transferring glycosyl groups
K7I03_RS22575	COG0531	amino acid
K7I03_RS22585	COG1028	Short-chain dehydrogenase reductase Sdr
K7I03_RS22600	COG2949	membrane
K7I03_RS22605	COG0232	Belongs to the dGTPase family. Type 2 subfamily
K7I03_RS22615	COG0358	DNA primase activity
K7I03_RS22620	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
K7I03_RS22625	COG1070	Carbohydrate kinase
K7I03_RS22655	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K7I03_RS22660	COG0588	phosphoglycerate mutase activity
K7I03_RS22670	COG3619	membrane
K7I03_RS22690	COG2130	NADP-dependent
K7I03_RS22695	COG1764	response to oxidative stress
K7I03_RS22710	COG1285	pathogenesis
K7I03_RS22725	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
K7I03_RS22730	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
K7I03_RS22735	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
K7I03_RS22740	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
K7I03_RS22765	COG0789	Transcriptional regulator
K7I03_RS22770	COG2197	response regulator
K7I03_RS22775	COG4585	Histidine kinase
K7I03_RS22790	COG1309	transcriptional regulator
K7I03_RS22795	COG0477	Major facilitator Superfamily
K7I03_RS22800	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
K7I03_RS22845	COG1358	cellular component organization or biogenesis
K7I03_RS22970	COG0406	alpha-ribazole phosphatase activity
K7I03_RS22995	COG5640	endopeptidase activity
K7I03_RS23030	COG1595	DNA-templated transcription, initiation
K7I03_RS23165	COG1309	transcriptional regulator
K7I03_RS23170	COG0438	transferase activity, transferring glycosyl groups
K7I03_RS23200	COG0860	N-Acetylmuramoyl-L-alanine amidase
K7I03_RS23210	COG2197	response regulator
K7I03_RS23215	COG4585	Histidine kinase
K7I03_RS23220	COG2030	dehydratase
K7I03_RS23235	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
K7I03_RS23240	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
K7I03_RS23310	COG0181	hydroxymethylbilane synthase activity
K7I03_RS23315	COG0494	nUDIX hydrolase
K7I03_RS23335	COG0557	exoribonuclease II activity
K7I03_RS23340	COG3022	response to hydroperoxide
K7I03_RS23425	COG2814	Major facilitator Superfamily
K7I03_RS23435	COG1834	amidinotransferase
K7I03_RS23460	COG0672	)-iron permease
K7I03_RS23465	COG2837	iron assimilation
K7I03_RS23470	COG2822	iron ion transport
K7I03_RS23480	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
K7I03_RS23500	COG4221	oxidoreductase activity
K7I03_RS23505	COG0346	lactoylglutathione lyase activity
K7I03_RS23540	COG0454	-acetyltransferase
K7I03_RS23545	COG2226	methyltransferase
K7I03_RS23585	COG1309	transcriptional regulator
K7I03_RS23665	COG1994	Peptidase M50
K7I03_RS23685	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
K7I03_RS23690	COG0477	Major facilitator Superfamily
K7I03_RS23695	COG1309	transcriptional regulator
K7I03_RS23715	COG0154	amidase activity
K7I03_RS23725	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
K7I03_RS23745	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
K7I03_RS23745	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
K7I03_RS23750	COG2132	Multicopper oxidase
K7I03_RS23760	COG0531	amino acid
K7I03_RS23785	COG0789	Transcriptional regulator
K7I03_RS23790	COG1819	glycosyl
K7I03_RS23820	COG0667	Aldo Keto reductase
K7I03_RS23825	COG0789	Transcriptional regulator
K7I03_RS23835	COG0174	glutamine synthetase
K7I03_RS23850	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
K7I03_RS23860	COG1609	Transcriptional regulator
K7I03_RS23865	COG0366	Alpha amylase catalytic
K7I03_RS23870	COG3833	ABC-type maltose transport systems, permease component
K7I03_RS23880	COG1653	transport
K7I03_RS23900	COG2365	Tyrosine phosphatase family
K7I03_RS23910	COG2197	response regulator
K7I03_RS23930	COG0745	RESPONSE REGULATOR receiver
K7I03_RS23935	COG1619	proteins homologs of microcin C7 resistance protein MccF
K7I03_RS23940	COG0671	phosphoesterase, PA-phosphatase related
K7I03_RS23945	COG1028	Short-chain dehydrogenase reductase Sdr
K7I03_RS24000	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
K7I03_RS24005	COG0321	lipoyl(octanoyl) transferase activity
K7I03_RS24045	COG0508	dehydrogenase complex catalyzes the overall conversion of
K7I03_RS24050	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K7I03_RS24055	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
K7I03_RS24060	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
K7I03_RS24075	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
K7I03_RS24075	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
K7I03_RS24080	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
K7I03_RS24115	COG4585	Histidine kinase
K7I03_RS24120	COG2197	response regulator
K7I03_RS24125	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
K7I03_RS24150	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
K7I03_RS24155	COG1104	cysteine desulfurase activity
K7I03_RS24160	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
K7I03_RS24165	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
K7I03_RS24175	COG1376	ErfK ybiS ycfS ynhG family protein
K7I03_RS24185	COG1845	cytochrome c oxidase, subunit III
K7I03_RS24190	COG2010	Cytochrome c
K7I03_RS24195	COG0723	plastoquinol--plastocyanin reductase activity
K7I03_RS24200	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
K7I03_RS24205	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
K7I03_RS24210	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
K7I03_RS24225	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
K7I03_RS24240	COG2409	Drug exporters of the RND superfamily
K7I03_RS24250	COG2226	methyltransferase
K7I03_RS24265	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K7I03_RS24285	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
K7I03_RS24290	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
K7I03_RS24345	COG0791	NLP P60 protein
K7I03_RS24430	COG0003	Pfam Anion-transporting ATPase
K7I03_RS24440	COG1940	carbohydrate kinase activity
K7I03_RS24475	COG2197	response regulator
K7I03_RS24480	COG0205	6-phosphofructokinase activity
K7I03_RS24485	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
K7I03_RS24490	COG2193	ferroxidase activity
K7I03_RS24495	COG0243	molybdopterin cofactor binding
K7I03_RS24500	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
K7I03_RS24515	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
K7I03_RS24520	COG0515	serine threonine protein kinase
K7I03_RS24520	COG2815	serine threonine protein kinase
K7I03_RS24525	COG2022	thiamine diphosphate biosynthetic process
K7I03_RS24535	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K7I03_RS24535	COG2022	thiamine diphosphate biosynthetic process
K7I03_RS24550	COG0352	thiamine-phosphate diphosphorylase activity
K7I03_RS24560	COG1132	(ABC) transporter
K7I03_RS24605	COG1309	transcriptional regulator
K7I03_RS24615	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
K7I03_RS24625	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
K7I03_RS24645	COG0714	Associated with various cellular activities
K7I03_RS24655	COG0275	rRNA processing
K7I03_RS24665	COG0768	penicillin binding
K7I03_RS24670	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
K7I03_RS24680	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
K7I03_RS24685	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
K7I03_RS24695	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
K7I03_RS24700	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
K7I03_RS24705	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
K7I03_RS24720	COG1799	cell septum assembly
K7I03_RS24730	COG3599	regulation of cell shape
K7I03_RS24735	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
K7I03_RS24750	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
K7I03_RS24765	COG0025	NhaP-type Na H and K H
K7I03_RS24805	COG0587	DNA-directed DNA polymerase activity
K7I03_RS24815	COG1432	Conserved Protein
K7I03_RS24850	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
K7I03_RS24855	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
K7I03_RS24860	COG0131	Imidazoleglycerol-phosphate dehydratase
K7I03_RS24870	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
K7I03_RS24875	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
K7I03_RS24880	COG0251	oxidation-reduction process
K7I03_RS24885	COG0107	imidazoleglycerol-phosphate synthase activity
K7I03_RS24900	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
K7I03_RS24925	COG0134	indole-3-glycerol-phosphate synthase activity
K7I03_RS24930	COG0133	tryptophan synthase activity
K7I03_RS24935	COG0159	tryptophan synthase activity
K7I03_RS24945	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
K7I03_RS24955	COG0067	glutamate synthase
K7I03_RS24955	COG0069	glutamate synthase activity
K7I03_RS24955	COG0070	glutamate synthase
K7I03_RS24970	COG1051	belongs to the nudix hydrolase family
K7I03_RS25015	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
K7I03_RS25020	COG1215	transferase activity, transferring glycosyl groups
K7I03_RS25055	COG2197	response regulator
K7I03_RS25065	COG0740	serine-type endopeptidase activity
K7I03_RS25070	COG0583	DNA-binding transcription factor activity
K7I03_RS25085	COG0287	Prephenate dehydrogenase
K7I03_RS25085	COG1605	Chorismate mutase
K7I03_RS25095	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
K7I03_RS25105	COG0737	Belongs to the 5'-nucleotidase family
K7I03_RS25140	COG0411	ABC transporter
K7I03_RS25160	COG2050	protein possibly involved in aromatic compounds catabolism
K7I03_RS25180	COG1643	Atp-dependent helicase
K7I03_RS25190	COG2226	methyltransferase
K7I03_RS25195	COG0539	negative regulation of cytoplasmic translation
K7I03_RS25205	COG0237	dephospho-CoA kinase activity
K7I03_RS25225	COG0584	glycerophosphoryl diester phosphodiesterase
K7I03_RS25230	COG0556	nucleotide-excision repair
K7I03_RS25235	COG2310	stress, protein
K7I03_RS25265	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
K7I03_RS25290	COG0322	excinuclease ABC activity
K7I03_RS25295	COG1660	Displays ATPase and GTPase activities
K7I03_RS25300	COG0391	Required for morphogenesis under gluconeogenic growth conditions
K7I03_RS25305	COG1481	regulation of sporulation
K7I03_RS25315	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
K7I03_RS25320	COG0126	phosphoglycerate kinase activity
K7I03_RS25325	COG0149	triose-phosphate isomerase activity
K7I03_RS25330	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
K7I03_RS25340	COG0166	Belongs to the GPI family
K7I03_RS25345	COG0363	glucosamine-6-phosphate deaminase activity
K7I03_RS25360	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
K7I03_RS25365	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
K7I03_RS25370	COG0109	protoheme IX farnesyltransferase activity
K7I03_RS25380	COG1612	heme a metabolic process
K7I03_RS25390	COG1131	(ABC) transporter
K7I03_RS25405	COG0719	Fe-S assembly protein
K7I03_RS25415	COG0396	ATPase activity
K7I03_RS25420	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
K7I03_RS25425	COG0822	iron-sulfur transferase activity
K7I03_RS25450	COG1309	transcriptional regulator
K7I03_RS25460	COG2076	Multidrug Resistance protein
K7I03_RS25465	COG3226	Transcriptional regulator
K7I03_RS25470	COG2171	N-acyltransferase activity
K7I03_RS25475	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
K7I03_RS25490	COG0702	epimerase
K7I03_RS25495	COG1733	regulation of RNA biosynthetic process
K7I03_RS25540	COG4977	sequence-specific DNA binding
K7I03_RS25570	COG1131	(ABC) transporter
K7I03_RS25595	COG0583	DNA-binding transcription factor activity
K7I03_RS25600	COG0251	oxidation-reduction process
K7I03_RS25660	COG0438	transferase activity, transferring glycosyl groups
K7I03_RS25680	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K7I03_RS25705	COG2197	response regulator
K7I03_RS25710	COG4585	Histidine kinase
K7I03_RS25715	COG2345	Transcriptional regulator
K7I03_RS25740	COG2080	2 iron, 2 sulfur cluster binding
K7I03_RS25745	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
K7I03_RS25750	COG1529	Aldehyde oxidase and xanthine dehydrogenase
K7I03_RS25760	COG1797	cobyrinic acid a,c-diamide synthase activity
K7I03_RS25775	COG1492	cobalamin metabolic process
K7I03_RS25795	COG0235	Class ii aldolase
K7I03_RS25820	COG0488	(ABC) transporter
K7I03_RS25830	COG1024	Enoyl-CoA hydratase
K7I03_RS25905	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K7I03_RS25910	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
K7I03_RS25930	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
K7I03_RS25945	COG1028	Short-chain dehydrogenase reductase Sdr
K7I03_RS25950	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
K7I03_RS25960	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K7I03_RS25965	COG2807	transmembrane transport
K7I03_RS25980	COG0560	Phosphoserine phosphatase
K7I03_RS25980	COG3830	Belongs to the UPF0237 family
K7I03_RS25990	COG1716	ATPase activity
K7I03_RS25990	COG0842	Transport permease protein
K7I03_RS25990	COG1131	(ABC) transporter
K7I03_RS26005	COG4585	Histidine kinase
K7I03_RS26010	COG2197	response regulator
K7I03_RS26030	COG1119	ATPase activity
K7I03_RS26055	COG1881	PFAM PEBP family protein
K7I03_RS26070	COG2094	Belongs to the DNA glycosylase MPG family
K7I03_RS26105	COG0647	UMP catabolic process
K7I03_RS26120	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K7I03_RS26125	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K7I03_RS26130	COG1120	ATPase activity
K7I03_RS26150	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
K7I03_RS26160	COG0497	DNA recombination
K7I03_RS26180	COG3387	PFAM Glycoside hydrolase 15-related
K7I03_RS26185	COG0504	CTP synthase activity
K7I03_RS26190	COG0494	nUDIX hydrolase
K7I03_RS26200	COG0686	Belongs to the AlaDH PNT family
K7I03_RS26225	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
K7I03_RS26230	COG1187	pseudouridine synthase activity
K7I03_RS26235	COG3541	Predicted nucleotidyltransferase
K7I03_RS26265	COG1160	GTP binding
K7I03_RS26280	COG0438	transferase activity, transferring glycosyl groups
K7I03_RS26290	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
K7I03_RS26300	COG0671	phosphoesterase, PA-phosphatase related
K7I03_RS26310	COG0477	Major facilitator Superfamily
K7I03_RS26315	COG1960	acyl-CoA dehydrogenase activity
K7I03_RS26320	COG1799	cell septum assembly
K7I03_RS26335	COG0330	HflC and HflK could
K7I03_RS26350	COG0587	DNA-directed DNA polymerase activity
K7I03_RS26355	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
K7I03_RS26390	COG0367	asparagine synthase
K7I03_RS26395	COG1725	Transcriptional regulator
K7I03_RS26430	COG0463	Glycosyl transferase, family 2
K7I03_RS26445	COG2755	lipolytic protein G-D-S-L family
K7I03_RS26455	COG2188	Transcriptional regulator
K7I03_RS26460	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
K7I03_RS26470	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
K7I03_RS26520	COG1846	Transcriptional regulator
K7I03_RS26525	COG2814	Major facilitator Superfamily
K7I03_RS26540	COG1028	Short-chain dehydrogenase reductase Sdr
K7I03_RS26550	COG3209	COG3209 Rhs family protein
K7I03_RS26560	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
K7I03_RS26580	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
K7I03_RS26585	COG0028	Belongs to the TPP enzyme family
K7I03_RS26595	COG0028	Belongs to the TPP enzyme family
K7I03_RS26600	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
K7I03_RS26615	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K7I03_RS26645	COG0667	Aldo Keto reductase
K7I03_RS26650	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K7I03_RS26665	COG0406	alpha-ribazole phosphatase activity
K7I03_RS26680	COG0215	cysteine-tRNA ligase activity
K7I03_RS26715	COG2186	Transcriptional regulator
K7I03_RS26750	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
K7I03_RS26755	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
K7I03_RS26760	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
K7I03_RS26765	COG1414	Transcriptional regulator
K7I03_RS26770	COG1410	methionine synthase
K7I03_RS26770	COG0646	methionine synthase
K7I03_RS26780	COG0747	negative chemotaxis
K7I03_RS26790	COG2197	response regulator
K7I03_RS26800	COG0517	IMP dehydrogenase activity
K7I03_RS26800	COG1994	Peptidase M50
K7I03_RS26820	COG1222	aaa ATPase
K7I03_RS26825	COG4122	O-methyltransferase activity
K7I03_RS26840	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
K7I03_RS26845	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
K7I03_RS26850	COG1609	Transcriptional regulator
K7I03_RS26860	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
K7I03_RS26895	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
K7I03_RS26900	COG0805	protein transport
K7I03_RS26940	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
K7I03_RS26945	COG4175	Glycine betaine
K7I03_RS26945	COG0517	IMP dehydrogenase activity
K7I03_RS26970	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
K7I03_RS26980	COG0174	glutamine synthetase
K7I03_RS27010	COG1404	Belongs to the peptidase S8 family
K7I03_RS27030	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
K7I03_RS27035	COG0291	Belongs to the bacterial ribosomal protein bL35 family
K7I03_RS27040	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
K7I03_RS27045	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
K7I03_RS27050	COG5002	protein histidine kinase activity
K7I03_RS27055	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
K7I03_RS27060	COG0072	phenylalanine-tRNA ligase activity
K7I03_RS27060	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K7I03_RS27090	COG1280	lysine exporter protein (LysE YggA)
K7I03_RS27115	COG1649	PFAM Uncharacterised BCR, COG1649
K7I03_RS27125	COG0697	spore germination
K7I03_RS27130	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K7I03_RS27145	COG1309	transcriptional regulator
K7I03_RS27170	COG2197	response regulator
K7I03_RS27180	COG0488	(ABC) transporter
K7I03_RS27205	COG4335	DNA alkylation repair
K7I03_RS27210	COG0477	Major facilitator Superfamily
K7I03_RS27215	COG2814	Major facilitator Superfamily
K7I03_RS27220	COG1846	Transcriptional regulator
K7I03_RS27280	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
K7I03_RS27285	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
K7I03_RS27290	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
K7I03_RS27295	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
K7I03_RS27300	COG1438	arginine binding
K7I03_RS27405	COG2197	response regulator
K7I03_RS27410	COG4585	Histidine kinase
K7I03_RS27435	COG0137	argininosuccinate synthase activity
K7I03_RS27440	COG0165	Argininosuccinate lyase
K7I03_RS27450	COG0477	Major facilitator Superfamily
K7I03_RS27455	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
K7I03_RS27460	COG0318	PFAM AMP-dependent synthetase and ligase
K7I03_RS27460	COG0204	Acyl-transferase
K7I03_RS27490	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
K7I03_RS27495	COG2011	ABC-type metal ion transport system permease component
K7I03_RS27500	COG1464	Belongs to the NlpA lipoprotein family
K7I03_RS27520	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
K7I03_RS27525	COG1648	precorrin-2 dehydrogenase activity
K7I03_RS27525	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
K7I03_RS27530	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
K7I03_RS27535	COG2124	cytochrome p450
K7I03_RS27585	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
K7I03_RS27635	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
K7I03_RS27650	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
K7I03_RS27680	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
K7I03_RS27690	COG0438	transferase activity, transferring glycosyl groups
K7I03_RS27705	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
K7I03_RS27710	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
K7I03_RS27715	COG0217	transcriptional regulatory protein
K7I03_RS27720	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
K7I03_RS27725	COG0632	four-way junction helicase activity
K7I03_RS27730	COG2255	four-way junction helicase activity
K7I03_RS27740	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
K7I03_RS27745	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
K7I03_RS27750	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
K7I03_RS27755	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
K7I03_RS27760	COG1196	nuclear chromosome segregation
K7I03_RS27765	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
K7I03_RS27775	COG0124	histidyl-tRNA synthetase
K7I03_RS27795	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
K7I03_RS27810	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
K7I03_RS27815	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
K7I03_RS27825	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
K7I03_RS27830	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
K7I03_RS27835	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
K7I03_RS27840	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
K7I03_RS27845	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
K7I03_RS27855	COG0006	proline dipeptidase activity
K7I03_RS27860	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
K7I03_RS27865	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
K7I03_RS27875	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
K7I03_RS27880	COG0540	Belongs to the ATCase OTCase family
K7I03_RS27885	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
K7I03_RS27895	COG0505	Belongs to the CarA family
K7I03_RS27900	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
K7I03_RS27905	COG0167	dihydroorotate dehydrogenase activity
K7I03_RS27910	COG0284	orotidine-5'-phosphate decarboxylase activity
K7I03_RS27935	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
K7I03_RS27950	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
K7I03_RS27960	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
K7I03_RS27965	COG2390	Transcriptional regulator
K7I03_RS27990	COG0531	amino acid
K7I03_RS28030	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
K7I03_RS28045	COG2233	PERMEase
K7I03_RS28055	COG0738	Major facilitator superfamily
K7I03_RS28070	COG3201	nicotinamide mononucleotide transporter
K7I03_RS28075	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
K7I03_RS28075	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
K7I03_RS28080	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
K7I03_RS28085	COG0140	phosphoribosyl-ATP diphosphatase activity
K7I03_RS28090	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
K7I03_RS28140	COG5001	Diguanylate cyclase
K7I03_RS28190	COG0574	Belongs to the PEP-utilizing enzyme family
K7I03_RS28190	COG3848	Pyruvate phosphate dikinase
K7I03_RS28195	COG1819	glycosyl
K7I03_RS28200	COG2409	Drug exporters of the RND superfamily
K7I03_RS28210	COG0702	epimerase
K7I03_RS28260	COG2814	Major facilitator Superfamily
K7I03_RS28275	COG2378	regulation of single-species biofilm formation
K7I03_RS28325	COG0142	geranyltranstransferase activity
K7I03_RS28330	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
K7I03_RS28355	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
K7I03_RS28360	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
K7I03_RS28365	COG3170	Tfp pilus assembly protein FimV
K7I03_RS28640	COG1278	Cold shock
K7I03_RS28665	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
K7I03_RS28745	COG4221	oxidoreductase activity
K7I03_RS28760	COG3387	PFAM Glycoside hydrolase 15-related
K7I03_RS28765	COG2814	Major facilitator Superfamily
K7I03_RS28770	COG1846	Transcriptional regulator
K7I03_RS28775	COG0657	acetylesterase activity
K7I03_RS28830	COG1914	H( )-stimulated, divalent metal cation uptake system
K7I03_RS28840	COG0583	DNA-binding transcription factor activity
K7I03_RS28885	COG1262	PFAM Formylglycine-generating sulfatase enzyme
K7I03_RS28890	COG0302	gtp cyclohydrolase
K7I03_RS28900	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
K7I03_RS28905	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
K7I03_RS28920	COG0720	synthase
K7I03_RS28925	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
K7I03_RS28930	COG0242	peptide deformylase activity
K7I03_RS29005	COG1012	belongs to the aldehyde dehydrogenase family
K7I03_RS29060	COG1120	ATPase activity
K7I03_RS29065	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K7I03_RS29080	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
K7I03_RS29080	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
K7I03_RS29080	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
K7I03_RS29110	COG1309	transcriptional regulator
K7I03_RS29115	COG1960	acyl-CoA dehydrogenase activity
K7I03_RS29140	COG0463	Glycosyl transferase, family 2
K7I03_RS29145	COG3030	protein affecting phage T7 exclusion by the F plasmid
K7I03_RS29160	COG2186	Transcriptional regulator
K7I03_RS29200	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
K7I03_RS29210	COG1793	dna ligase
K7I03_RS29245	COG0438	transferase activity, transferring glycosyl groups
K7I03_RS29250	COG1984	allophanate hydrolase subunit 2
K7I03_RS29255	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
K7I03_RS29260	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
K7I03_RS29265	COG1802	Transcriptional regulator
K7I03_RS29320	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K7I03_RS29330	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
K7I03_RS29360	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
K7I03_RS29405	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
K7I03_RS29415	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
K7I03_RS29415	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
K7I03_RS29445	COG1695	Transcriptional regulator
K7I03_RS29475	COG0697	spore germination
K7I03_RS29510	COG1028	Short-chain dehydrogenase reductase Sdr
K7I03_RS29515	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
K7I03_RS29535	COG2378	regulation of single-species biofilm formation
K7I03_RS29545	COG2318	DinB family
K7I03_RS29555	COG0815	Transfers the fatty acyl group on membrane lipoproteins
K7I03_RS29600	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
K7I03_RS29605	COG3285	dna ligase
K7I03_RS29605	COG1793	dna ligase
K7I03_RS29610	COG1796	DNA polymerase
K7I03_RS29610	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
K7I03_RS29660	COG0640	Transcriptional regulator
K7I03_RS29680	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
K7I03_RS29795	COG1120	ATPase activity
K7I03_RS29800	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K7I03_RS29805	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K7I03_RS29810	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K7I03_RS29840	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
K7I03_RS29850	COG1247	-acetyltransferase
K7I03_RS29935	COG1660	Displays ATPase and GTPase activities
K7I03_RS29965	COG1595	DNA-templated transcription, initiation
K7I03_RS29985	COG0445	tRNA wobble uridine modification
K7I03_RS30015	COG2223	nitrite transmembrane transporter activity
K7I03_RS30030	COG4977	sequence-specific DNA binding
K7I03_RS30045	COG0464	growth
K7I03_RS30055	COG3217	Mosc domain protein beta barrel domain protein
K7I03_RS30055	COG0633	Ferredoxin
K7I03_RS30070	COG1215	transferase activity, transferring glycosyl groups
K7I03_RS30075	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
K7I03_RS30095	COG2376	Dihydroxyacetone kinase
K7I03_RS30125	COG0302	gtp cyclohydrolase
K7I03_RS30200	COG0574	Belongs to the PEP-utilizing enzyme family
K7I03_RS30200	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
K7I03_RS30210	COG2197	response regulator
K7I03_RS30280	COG0076	glutamate decarboxylase activity
K7I03_RS30345	COG3903	Transcriptional regulator
K7I03_RS30345	COG3629	intracellular signal transduction
K7I03_RS30365	COG0405	Gamma-glutamyltransferase
K7I03_RS30370	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K7I03_RS30385	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K7I03_RS30445	COG2340	Cysteine-rich secretory protein family
K7I03_RS30500	COG0500	methyltransferase
K7I03_RS30510	COG0367	asparagine synthase
K7I03_RS30515	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
K7I03_RS30530	COG2197	response regulator
K7I03_RS30545	COG0671	phosphoesterase, PA-phosphatase related
K7I03_RS30550	COG0515	serine threonine protein kinase
K7I03_RS30560	COG1733	regulation of RNA biosynthetic process
K7I03_RS30565	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
K7I03_RS30635	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
K7I03_RS30640	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
K7I03_RS30690	COG1793	dna ligase
K7I03_RS30720	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
K7I03_RS30740	COG1280	lysine exporter protein (LysE YggA)
K7I03_RS30750	COG0515	serine threonine protein kinase
K7I03_RS30760	COG0596	Alpha beta hydrolase
K7I03_RS30780	COG0438	transferase activity, transferring glycosyl groups
K7I03_RS30795	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
K7I03_RS30815	COG0791	NLP P60 protein
K7I03_RS30830	COG3012	SEC-C Motif Domain Protein
K7I03_RS30880	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
K7I03_RS30905	COG1522	sequence-specific DNA binding
K7I03_RS30915	COG0667	Aldo Keto reductase
K7I03_RS30920	COG1733	regulation of RNA biosynthetic process
K7I03_RS30950	COG0702	epimerase
K7I03_RS30975	COG0477	Major facilitator Superfamily
K7I03_RS31010	COG2814	Major facilitator Superfamily
K7I03_RS31015	COG1316	TRANSCRIPTIONal
K7I03_RS31090	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
K7I03_RS31095	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
K7I03_RS31105	COG0604	alcohol dehydrogenase
K7I03_RS31105	COG3321	synthase
K7I03_RS31110	COG0596	Alpha beta hydrolase
K7I03_RS31115	COG0477	Major facilitator Superfamily
K7I03_RS31140	COG0604	alcohol dehydrogenase
K7I03_RS31140	COG3321	synthase
K7I03_RS31150	COG0604	alcohol dehydrogenase
K7I03_RS31150	COG3321	synthase
K7I03_RS31210	COG1028	Short-chain dehydrogenase reductase Sdr
K7I03_RS31215	COG1959	2 iron, 2 sulfur cluster binding
K7I03_RS31220	COG0697	spore germination
K7I03_RS31235	COG0583	DNA-binding transcription factor activity
K7I03_RS31240	COG0596	Alpha beta hydrolase
K7I03_RS31250	COG0179	Fumarylacetoacetate (FAA) hydrolase
K7I03_RS31305	COG1028	Short-chain dehydrogenase reductase Sdr
K7I03_RS31310	COG2030	dehydratase
K7I03_RS31315	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K7I03_RS31340	COG0673	inositol 2-dehydrogenase activity
K7I03_RS31350	COG1028	Short-chain dehydrogenase reductase Sdr
K7I03_RS31385	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
K7I03_RS31400	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
K7I03_RS31420	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
K7I03_RS31445	COG0583	DNA-binding transcription factor activity
K7I03_RS31460	COG0655	NAD(P)H dehydrogenase (quinone) activity
K7I03_RS31480	COG1683	Conserved Protein
K7I03_RS31485	COG2318	DinB family
K7I03_RS31515	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
K7I03_RS31535	COG1051	belongs to the nudix hydrolase family
K7I03_RS31555	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
K7I03_RS31575	COG0028	Belongs to the TPP enzyme family
K7I03_RS31600	COG1309	transcriptional regulator
K7I03_RS31700	COG3265	gluconokinase activity
K7I03_RS31730	COG0318	PFAM AMP-dependent synthetase and ligase
K7I03_RS31755	COG2223	nitrite transmembrane transporter activity
K7I03_RS31765	COG1278	Cold shock
K7I03_RS31770	COG3321	synthase
K7I03_RS31770	COG1028	Short-chain dehydrogenase reductase Sdr
K7I03_RS31770	COG0604	alcohol dehydrogenase
K7I03_RS31775	COG1834	amidinotransferase
K7I03_RS31785	COG2030	dehydratase
K7I03_RS31795	COG2301	Belongs to the HpcH HpaI aldolase family
K7I03_RS31810	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
K7I03_RS31820	COG2234	aminopeptidase activity
K7I03_RS31825	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
K7I03_RS31830	COG2205	protein histidine kinase activity
K7I03_RS31835	COG0745	RESPONSE REGULATOR receiver
K7I03_RS31855	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
K7I03_RS31875	COG2011	ABC-type metal ion transport system permease component
K7I03_RS31880	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
K7I03_RS31885	COG1464	Belongs to the NlpA lipoprotein family
K7I03_RS31890	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
K7I03_RS31900	COG1482	cell wall glycoprotein biosynthetic process
K7I03_RS31905	COG1028	Short-chain dehydrogenase reductase Sdr
K7I03_RS31920	COG1028	Short-chain dehydrogenase reductase Sdr
K7I03_RS31935	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K7I03_RS31935	COG0723	plastoquinol--plastocyanin reductase activity
K7I03_RS31975	COG1028	Short-chain dehydrogenase reductase Sdr
K7I03_RS31980	COG1573	uracil-dna glycosylase
K7I03_RS32005	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
K7I03_RS32010	COG0438	transferase activity, transferring glycosyl groups
K7I03_RS32035	COG2192	nodulation
K7I03_RS32085	COG1982	Orn Lys Arg decarboxylase major
K7I03_RS32090	COG0640	Transcriptional regulator
K7I03_RS32095	COG2814	Major facilitator Superfamily
K7I03_RS32135	COG4585	Histidine kinase
K7I03_RS32150	COG2267	carboxylic ester hydrolase activity
K7I03_RS32170	COG0243	molybdopterin cofactor binding
K7I03_RS32175	COG2146	nitrite reductase [NAD(P)H] activity
K7I03_RS32175	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
K7I03_RS32180	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
K7I03_RS32180	COG2146	nitrite reductase [NAD(P)H] activity
K7I03_RS32190	COG2223	nitrite transmembrane transporter activity
K7I03_RS32220	COG0583	DNA-binding transcription factor activity
K7I03_RS32225	COG1073	alpha beta
K7I03_RS32225	COG2226	methyltransferase
K7I03_RS32265	COG2813	Specifically methylates the guanine in position
K7I03_RS32270	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
K7I03_RS32275	COG2814	Major facilitator Superfamily
K7I03_RS32300	COG2814	Major facilitator Superfamily
K7I03_RS32340	COG2814	Major facilitator Superfamily
K7I03_RS32355	COG3979	chitinase
K7I03_RS32365	COG1366	Belongs to the anti-sigma-factor antagonist family
K7I03_RS32365	COG2172	sigma factor antagonist activity
K7I03_RS32365	COG2208	phosphoserine phosphatase activity
K7I03_RS32370	COG0475	glutathione-regulated potassium exporter activity
K7I03_RS32370	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
K7I03_RS32380	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
K7I03_RS32385	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
K7I03_RS32390	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
K7I03_RS32395	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
K7I03_RS32400	COG3486	L-lysine 6-monooxygenase (NADPH) activity
K7I03_RS32405	COG3433	isochorismatase activity
K7I03_RS32405	COG1535	isochorismatase
K7I03_RS32410	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
K7I03_RS32430	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K7I03_RS32440	COG1132	(ABC) transporter
K7I03_RS32445	COG1132	(ABC) transporter
K7I03_RS32450	COG2375	cellular response to nickel ion
K7I03_RS32455	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K7I03_RS32460	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K7I03_RS32465	COG0473	3-isopropylmalate dehydrogenase activity
K7I03_RS32480	COG3135	benzoate transporter
K7I03_RS32495	COG2207	Transcriptional regulator
K7I03_RS32525	COG1028	Short-chain dehydrogenase reductase Sdr
K7I03_RS32555	COG1295	ribonuclease BN
K7I03_RS32585	COG0789	Transcriptional regulator
K7I03_RS32595	COG1028	Short-chain dehydrogenase reductase Sdr
K7I03_RS32610	COG2175	clavaminate synthase activity
K7I03_RS32625	COG0318	PFAM AMP-dependent synthetase and ligase
K7I03_RS32625	COG3321	synthase
K7I03_RS32625	COG1028	Short-chain dehydrogenase reductase Sdr
K7I03_RS32625	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K7I03_RS32625	COG0300	oxidoreductase activity
K7I03_RS32640	COG0726	polysaccharide deacetylase
K7I03_RS32675	COG0387	Pfam Sodium calcium exchanger
K7I03_RS32700	COG0456	acetyltransferase
K7I03_RS32705	COG1335	isochorismatase
K7I03_RS32740	COG2264	protein methyltransferase activity
K7I03_RS32785	COG1597	lipid kinase activity
K7I03_RS32815	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
K7I03_RS32825	COG0477	Major facilitator Superfamily
K7I03_RS32865	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K7I03_RS32875	COG2814	Major facilitator Superfamily
K7I03_RS32900	COG2353	YceI-like domain
K7I03_RS32950	COG1472	Belongs to the glycosyl hydrolase 3 family
K7I03_RS32965	COG0019	diaminopimelate decarboxylase activity
K7I03_RS33120	COG0110	maltose O-acetyltransferase activity
K7I03_RS33130	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K7I03_RS33150	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K7I03_RS33155	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
K7I03_RS33160	COG3251	PFAM MbtH domain protein
K7I03_RS33165	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K7I03_RS33170	COG3629	intracellular signal transduction
K7I03_RS33170	COG3903	Transcriptional regulator
K7I03_RS33205	COG2072	flavoprotein involved in K transport
K7I03_RS33265	COG1595	DNA-templated transcription, initiation
K7I03_RS33275	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
K7I03_RS33295	COG0076	glutamate decarboxylase activity
K7I03_RS33320	COG1309	transcriptional regulator
K7I03_RS33345	COG0242	peptide deformylase activity
K7I03_RS33370	COG3693	PFAM glycoside hydrolase, family 10
K7I03_RS33425	COG1028	Short-chain dehydrogenase reductase Sdr
K7I03_RS33590	COG2188	Transcriptional regulator
K7I03_RS33705	COG3903	Transcriptional regulator
K7I03_RS33705	COG3629	intracellular signal transduction
K7I03_RS33790	COG1686	Belongs to the peptidase S11 family
K7I03_RS33800	COG2124	cytochrome p450
K7I03_RS33855	COG2205	protein histidine kinase activity
K7I03_RS33860	COG0741	lytic transglycosylase activity
K7I03_RS33860	COG0791	NLP P60 protein
K7I03_RS33885	COG2197	response regulator
K7I03_RS33970	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system