locus-tag	class	description
JGK51_RS00005	COG0006	proline dipeptidase activity
JGK51_RS00020	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JGK51_RS00040	COG1999	signal sequence binding
JGK51_RS00055	COG2837	iron assimilation
JGK51_RS00065	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JGK51_RS00070	COG0561	phosphatase activity
JGK51_RS00095	COG1131	(ABC) transporter
JGK51_RS00110	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
JGK51_RS00120	COG0561	phosphatase activity
JGK51_RS00125	COG4988	ABC transporter
JGK51_RS00130	COG1294	oxidase, subunit
JGK51_RS00135	COG1271	oxidase subunit
JGK51_RS00140	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JGK51_RS00145	COG1609	Transcriptional regulator
JGK51_RS00160	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
JGK51_RS00175	COG1414	Transcriptional regulator
JGK51_RS00185	COG0662	Cupin 2, conserved barrel domain protein
JGK51_RS00190	COG1950	PFAM Membrane protein of
JGK51_RS00195	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JGK51_RS00200	COG0626	cystathionine gamma-synthase activity
JGK51_RS00225	COG2814	Major facilitator Superfamily
JGK51_RS00255	COG0305	Participates in initiation and elongation during chromosome replication
JGK51_RS00265	COG0359	binds to the 23S rRNA
JGK51_RS00270	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JGK51_RS00275	COG0629	single-stranded DNA binding
JGK51_RS00280	COG0360	Binds together with S18 to 16S ribosomal RNA
JGK51_RS00305	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JGK51_RS00315	COG1260	myo-inositol-1-phosphate synthase
JGK51_RS00325	COG0617	tRNA 3'-terminal CCA addition
JGK51_RS00340	COG2815	serine threonine protein kinase
JGK51_RS00340	COG0515	serine threonine protein kinase
JGK51_RS00345	COG1595	DNA-templated transcription, initiation
JGK51_RS00355	COG0492	ferredoxin-NADP+ reductase activity
JGK51_RS00360	COG3118	belongs to the thioredoxin family
JGK51_RS00375	COG1192	Involved in chromosome partitioning
JGK51_RS00380	COG0357	Ribosomal RNA small subunit methyltransferase G
JGK51_RS00390	COG0706	membrane insertase activity
JGK51_RS00395	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
JGK51_RS00400	COG0594	ribonuclease P activity
JGK51_RS00405	COG0230	Belongs to the bacterial ribosomal protein bL34 family
JGK51_RS00410	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JGK51_RS00415	COG0592	DNA-directed DNA polymerase activity
JGK51_RS00420	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
JGK51_RS00425	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JGK51_RS00430	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
JGK51_RS00435	COG0187	DNA topoisomerase II activity
JGK51_RS00440	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JGK51_RS00445	COG3266	domain, Protein
JGK51_RS00470	COG4249	Peptidase C14 caspase catalytic subunit p20
JGK51_RS00470	COG2319	Wd-40 repeat
JGK51_RS00505	COG0515	serine threonine protein kinase
JGK51_RS00540	COG0705	Rhomboid family
JGK51_RS00555	COG3764	Sortase (surface protein transpeptidase)
JGK51_RS00570	COG3764	Sortase (surface protein transpeptidase)
JGK51_RS00575	COG3764	Sortase (surface protein transpeptidase)
JGK51_RS00580	COG0515	serine threonine protein kinase
JGK51_RS00585	COG0768	penicillin binding
JGK51_RS00595	COG3266	domain, Protein
JGK51_RS00595	COG0631	protein serine/threonine phosphatase activity
JGK51_RS00600	COG1716	ATPase activity
JGK51_RS00605	COG1716	ATPase activity
JGK51_RS00645	COG0477	Major facilitator Superfamily
JGK51_RS00675	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JGK51_RS00680	COG2151	metal-sulfur cluster biosynthetic enzyme
JGK51_RS00685	COG3396	Phenylacetate-CoA oxygenase
JGK51_RS00690	COG3460	Phenylacetate-CoA oxygenase
JGK51_RS00695	COG3396	Phenylacetate-CoA oxygenase
JGK51_RS00720	COG1250	3-hydroxyacyl-CoA dehydrogenase
JGK51_RS00725	COG1309	transcriptional regulator
JGK51_RS00730	COG1522	sequence-specific DNA binding
JGK51_RS00755	COG0303	'Molybdopterin
JGK51_RS00760	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JGK51_RS00765	COG1028	Short-chain dehydrogenase reductase Sdr
JGK51_RS00765	COG0604	alcohol dehydrogenase
JGK51_RS00765	COG3321	synthase
JGK51_RS00780	COG0515	serine threonine protein kinase
JGK51_RS00785	COG0515	serine threonine protein kinase
JGK51_RS00800	COG0022	dehydrogenase e1 component
JGK51_RS00805	COG0508	dehydrogenase complex catalyzes the overall conversion of
JGK51_RS00840	COG2271	Major facilitator Superfamily
JGK51_RS00875	COG1362	aminopeptidase activity
JGK51_RS00880	COG1960	acyl-CoA dehydrogenase activity
JGK51_RS00890	COG1741	Belongs to the pirin family
JGK51_RS00905	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
JGK51_RS00915	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JGK51_RS00925	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JGK51_RS00975	COG1957	nucleoside hydrolase
JGK51_RS00980	COG0366	Alpha amylase catalytic
JGK51_RS01020	COG2255	four-way junction helicase activity
JGK51_RS01030	COG0701	Predicted permease
JGK51_RS01050	COG2188	Transcriptional regulator
JGK51_RS01055	COG2814	Major facilitator Superfamily
JGK51_RS01070	COG1595	DNA-templated transcription, initiation
JGK51_RS01080	COG1309	transcriptional regulator
JGK51_RS01085	COG1028	Short-chain dehydrogenase reductase Sdr
JGK51_RS01100	COG0659	secondary active sulfate transmembrane transporter activity
JGK51_RS01105	COG3629	intracellular signal transduction
JGK51_RS01105	COG3903	Transcriptional regulator
JGK51_RS01150	COG1278	Cold shock
JGK51_RS01160	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JGK51_RS01200	COG1819	glycosyl
JGK51_RS01205	COG0789	Transcriptional regulator
JGK51_RS01210	COG0385	Bile acid
JGK51_RS01220	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JGK51_RS01245	COG0717	Belongs to the dCTP deaminase family
JGK51_RS01250	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
JGK51_RS01270	COG0247	lactate metabolic process
JGK51_RS01270	COG2181	nitrate reductase activity
JGK51_RS01275	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JGK51_RS01280	COG0443	Heat shock 70 kDa protein
JGK51_RS01285	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JGK51_RS01290	COG0484	heat shock protein binding
JGK51_RS01295	COG0789	Transcriptional regulator
JGK51_RS01300	COG4213	ABC transporter substrate-binding protein
JGK51_RS01330	COG0542	response to heat
JGK51_RS01365	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
JGK51_RS01380	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JGK51_RS01390	COG0477	Major facilitator Superfamily
JGK51_RS01400	COG3483	tryptophan 2,3-dioxygenase activity
JGK51_RS01405	COG3844	kynureninase activity
JGK51_RS01450	COG4585	Histidine kinase
JGK51_RS01455	COG2197	response regulator
JGK51_RS01460	COG4585	Histidine kinase
JGK51_RS01465	COG2197	response regulator
JGK51_RS01480	COG3559	Exporter of polyketide antibiotics
JGK51_RS01485	COG1131	(ABC) transporter
JGK51_RS01505	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JGK51_RS01510	COG0737	Belongs to the 5'-nucleotidase family
JGK51_RS01520	COG1802	Transcriptional regulator
JGK51_RS01525	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JGK51_RS01545	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JGK51_RS01550	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JGK51_RS01570	COG1595	DNA-templated transcription, initiation
JGK51_RS01600	COG1937	Protein conserved in bacteria
JGK51_RS01615	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JGK51_RS01645	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JGK51_RS01660	COG0039	L-malate dehydrogenase activity
JGK51_RS01945	COG1475	DNA binding
JGK51_RS02235	COG1609	Transcriptional regulator
JGK51_RS02250	COG1408	metallophosphoesterase
JGK51_RS02270	COG0003	Pfam Anion-transporting ATPase
JGK51_RS02295	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JGK51_RS02330	COG2267	carboxylic ester hydrolase activity
JGK51_RS02345	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JGK51_RS02405	COG1111	helicase
JGK51_RS02405	COG1205	dead DEAH box helicase
JGK51_RS02410	COG1366	Belongs to the anti-sigma-factor antagonist family
JGK51_RS02415	COG2172	sigma factor antagonist activity
JGK51_RS02420	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
JGK51_RS02440	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JGK51_RS02440	COG1754	DNA topoisomerase type I activity
JGK51_RS02445	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JGK51_RS02500	COG0494	nUDIX hydrolase
JGK51_RS02590	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JGK51_RS02590	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JGK51_RS02630	COG1012	belongs to the aldehyde dehydrogenase family
JGK51_RS02635	COG2318	DinB family
JGK51_RS02640	COG0076	glutamate decarboxylase activity
JGK51_RS02645	COG0789	Transcriptional regulator
JGK51_RS02650	COG0393	Putative heavy-metal-binding
JGK51_RS02655	COG0586	Pfam SNARE associated Golgi protein
JGK51_RS02665	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
JGK51_RS02680	COG0037	tRNA processing
JGK51_RS02695	COG0302	gtp cyclohydrolase
JGK51_RS02710	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JGK51_RS02740	COG0649	NAD binding
JGK51_RS02755	COG2197	response regulator
JGK51_RS02770	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
JGK51_RS02775	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
JGK51_RS02785	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
JGK51_RS02805	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
JGK51_RS02845	COG0477	Major facilitator Superfamily
JGK51_RS02860	COG2205	protein histidine kinase activity
JGK51_RS02865	COG0745	RESPONSE REGULATOR receiver
JGK51_RS02875	COG1595	DNA-templated transcription, initiation
JGK51_RS02880	COG1194	a g-specific adenine glycosylase
JGK51_RS02890	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
JGK51_RS02910	COG0248	Ppx GppA phosphatase
JGK51_RS02915	COG1082	Xylose isomerase domain protein TIM barrel
JGK51_RS02925	COG0129	dihydroxy-acid dehydratase activity
JGK51_RS02930	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JGK51_RS02930	COG0515	serine threonine protein kinase
JGK51_RS02935	COG4991	sh3 domain protein
JGK51_RS02950	COG0842	Transport permease protein
JGK51_RS02950	COG1129	ABC transporter
JGK51_RS02965	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JGK51_RS03000	COG2223	nitrite transmembrane transporter activity
JGK51_RS03005	COG0123	including yeast histone deacetylase and acetoin utilization protein
JGK51_RS03055	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
JGK51_RS03060	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
JGK51_RS03065	COG0181	hydroxymethylbilane synthase activity
JGK51_RS03070	COG1648	precorrin-2 dehydrogenase activity
JGK51_RS03070	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JGK51_RS03100	COG1396	sequence-specific DNA binding
JGK51_RS03100	COG3800	Transcriptional regulator
JGK51_RS03145	COG0113	porphobilinogen synthase activity
JGK51_RS03150	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JGK51_RS03155	COG2910	NAD(P)H-binding
JGK51_RS03195	COG0018	arginyl-trna synthetase
JGK51_RS03200	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
JGK51_RS03235	COG1690	Belongs to the RtcB family
JGK51_RS03260	COG1742	UPF0060 membrane protein
JGK51_RS03265	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JGK51_RS03280	COG2205	protein histidine kinase activity
JGK51_RS03285	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
JGK51_RS03285	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
JGK51_RS03295	COG2362	D-Aminopeptidase
JGK51_RS03325	COG2815	serine threonine protein kinase
JGK51_RS03325	COG0515	serine threonine protein kinase
JGK51_RS03335	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JGK51_RS03340	COG0406	alpha-ribazole phosphatase activity
JGK51_RS03355	COG0785	Cytochrome C biogenesis protein
JGK51_RS03360	COG1333	cytochrome c biogenesis protein
JGK51_RS03365	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JGK51_RS03415	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
JGK51_RS03425	COG0163	prenyltransferase activity
JGK51_RS03435	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
JGK51_RS03445	COG1573	uracil-dna glycosylase
JGK51_RS03460	COG1309	transcriptional regulator
JGK51_RS03475	COG4585	Histidine kinase
JGK51_RS03480	COG2197	response regulator
JGK51_RS03485	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JGK51_RS03505	COG1215	transferase activity, transferring glycosyl groups
JGK51_RS03565	COG3629	intracellular signal transduction
JGK51_RS03580	COG2226	methyltransferase
JGK51_RS03585	COG1278	Cold shock
JGK51_RS03590	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
JGK51_RS03610	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
JGK51_RS03620	COG2226	methyltransferase
JGK51_RS03640	COG0242	peptide deformylase activity
JGK51_RS03655	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JGK51_RS03660	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JGK51_RS03665	COG0649	NAD binding
JGK51_RS03675	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
JGK51_RS03680	COG1034	ATP synthesis coupled electron transport
JGK51_RS03685	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
JGK51_RS03690	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JGK51_RS03695	COG0839	Belongs to the complex I subunit 6 family
JGK51_RS03700	COG0713	ATP synthesis coupled electron transport
JGK51_RS03705	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JGK51_RS03715	COG1007	ATP synthesis coupled electron transport
JGK51_RS03725	COG0514	ATP-dependent DNA helicase (RecQ)
JGK51_RS03740	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JGK51_RS03745	COG0492	ferredoxin-NADP+ reductase activity
JGK51_RS03750	COG0561	phosphatase activity
JGK51_RS03755	COG5412	phage tail tape measure protein
JGK51_RS03755	COG3953	SLT domain
JGK51_RS03760	COG0142	geranyltranstransferase activity
JGK51_RS03795	COG0702	epimerase
JGK51_RS03800	COG1013	pyruvate-flavodoxin oxidoreductase activity
JGK51_RS03805	COG0674	pyruvate-flavodoxin oxidoreductase activity
JGK51_RS03805	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
JGK51_RS03810	COG2197	response regulator
JGK51_RS03825	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JGK51_RS03830	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JGK51_RS03835	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JGK51_RS03840	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
JGK51_RS03845	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JGK51_RS03850	COG0839	Belongs to the complex I subunit 6 family
JGK51_RS03855	COG0713	ATP synthesis coupled electron transport
JGK51_RS03865	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JGK51_RS03870	COG1007	ATP synthesis coupled electron transport
JGK51_RS03875	COG0501	Belongs to the peptidase M48B family
JGK51_RS03890	COG2261	transglycosylase associated protein
JGK51_RS03895	COG1666	GTP binding
JGK51_RS03910	COG1595	DNA-templated transcription, initiation
JGK51_RS03930	COG0702	epimerase
JGK51_RS03950	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JGK51_RS03955	COG2030	dehydratase
JGK51_RS04005	COG3629	intracellular signal transduction
JGK51_RS04005	COG3903	Transcriptional regulator
JGK51_RS04010	COG0812	UDP-N-acetylmuramate dehydrogenase activity
JGK51_RS04015	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
JGK51_RS04020	COG0436	Aminotransferase
JGK51_RS04035	COG0250	Participates in transcription elongation, termination and antitermination
JGK51_RS04040	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
JGK51_RS04045	COG0081	regulation of translation
JGK51_RS04055	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JGK51_RS04060	COG0222	ribosome binding
JGK51_RS04065	COG0085	RNA polymerase activity
JGK51_RS04070	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JGK51_RS04195	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
JGK51_RS04200	COG0049	tRNA binding
JGK51_RS04205	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JGK51_RS04265	COG1511	domain protein
JGK51_RS04275	COG0051	transcription antitermination factor activity, RNA binding
JGK51_RS04280	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JGK51_RS04285	COG0088	Forms part of the polypeptide exit tunnel
JGK51_RS04290	COG0089	rRNA binding
JGK51_RS04295	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JGK51_RS04300	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JGK51_RS04305	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JGK51_RS04310	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JGK51_RS04315	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JGK51_RS04320	COG0255	Belongs to the universal ribosomal protein uL29 family
JGK51_RS04325	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JGK51_RS04330	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JGK51_RS04335	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JGK51_RS04340	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JGK51_RS04345	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JGK51_RS04350	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JGK51_RS04355	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JGK51_RS04360	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JGK51_RS04365	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JGK51_RS04370	COG1841	ribosomal large subunit assembly
JGK51_RS04375	COG0200	Binds to the 23S rRNA
JGK51_RS04385	COG0563	adenylate kinase activity
JGK51_RS04395	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JGK51_RS04400	COG0257	Belongs to the bacterial ribosomal protein bL36 family
JGK51_RS04405	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JGK51_RS04410	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JGK51_RS04415	COG0202	RNA polymerase activity
JGK51_RS04420	COG0203	ribosomal protein L17
JGK51_RS04425	COG0101	tRNA pseudouridine synthase activity
JGK51_RS04435	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JGK51_RS04440	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
JGK51_RS04445	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JGK51_RS04455	COG1072	(Pantothenic acid kinase))
JGK51_RS04465	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JGK51_RS04470	COG1028	Short-chain dehydrogenase reductase Sdr
JGK51_RS04475	COG0736	holo-[acyl-carrier-protein] synthase activity
JGK51_RS04485	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JGK51_RS04495	COG0802	atpase or kinase
JGK51_RS04515	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JGK51_RS04535	COG1175	transmembrane transport
JGK51_RS04540	COG1653	transport
JGK51_RS04560	COG0726	polysaccharide deacetylase
JGK51_RS04565	COG0726	polysaccharide deacetylase
JGK51_RS04575	COG0459	protein refolding
JGK51_RS04590	COG4221	oxidoreductase activity
JGK51_RS04600	COG0583	DNA-binding transcription factor activity
JGK51_RS04610	COG2197	response regulator
JGK51_RS04615	COG1595	DNA-templated transcription, initiation
JGK51_RS04625	COG0516	GMP reductase activity
JGK51_RS04640	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
JGK51_RS04650	COG0515	serine threonine protein kinase
JGK51_RS04650	COG2815	serine threonine protein kinase
JGK51_RS04655	COG0515	serine threonine protein kinase
JGK51_RS04660	COG0515	serine threonine protein kinase
JGK51_RS04660	COG2815	serine threonine protein kinase
JGK51_RS04665	COG0515	serine threonine protein kinase
JGK51_RS04675	COG1012	belongs to the aldehyde dehydrogenase family
JGK51_RS04690	COG0519	Catalyzes the synthesis of GMP from XMP
JGK51_RS04690	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JGK51_RS04730	COG2197	response regulator
JGK51_RS04735	COG0791	NLP P60 protein
JGK51_RS04755	COG0739	heme binding
JGK51_RS04765	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
JGK51_RS04765	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
JGK51_RS04780	COG0714	Associated with various cellular activities
JGK51_RS04795	COG3552	Protein containing von Willebrand factor type A (VWA) domain
JGK51_RS04800	COG0045	succinate-CoA ligase (ADP-forming) activity
JGK51_RS04830	COG0138	bifunctional purine biosynthesis protein purh
JGK51_RS04840	COG0515	serine threonine protein kinase
JGK51_RS04840	COG2815	serine threonine protein kinase
JGK51_RS04855	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JGK51_RS04870	COG0039	L-malate dehydrogenase activity
JGK51_RS04875	COG0477	Major facilitator Superfamily
JGK51_RS04885	COG1012	belongs to the aldehyde dehydrogenase family
JGK51_RS04895	COG0517	IMP dehydrogenase activity
JGK51_RS04895	COG4175	Glycine betaine
JGK51_RS04900	COG4176	ABC-type proline glycine betaine transport system permease component
JGK51_RS04915	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JGK51_RS04920	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JGK51_RS04945	COG0754	glutathionylspermidine amidase activity
JGK51_RS04950	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JGK51_RS04955	COG0180	Tryptophanyl-tRNA synthetase
JGK51_RS04970	COG1295	ribonuclease BN
JGK51_RS04990	COG1309	transcriptional regulator
JGK51_RS05010	COG1053	succinate dehydrogenase
JGK51_RS05020	COG2009	succinate dehydrogenase
JGK51_RS05030	COG3525	Glycosyl hydrolase, family 20, catalytic domain
JGK51_RS05070	COG1595	DNA-templated transcription, initiation
JGK51_RS05085	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
JGK51_RS05085	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
JGK51_RS05110	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
JGK51_RS05120	COG1216	Glycosyl transferase, family 2
JGK51_RS05135	COG2089	acid synthase
JGK51_RS05165	COG2226	methyltransferase
JGK51_RS05170	COG1473	amidohydrolase
JGK51_RS05170	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
JGK51_RS05175	COG1744	ABC transporter substrate-binding protein PnrA-like
JGK51_RS05180	COG3845	ABC transporter
JGK51_RS05185	COG4603	Belongs to the binding-protein-dependent transport system permease family
JGK51_RS05190	COG1079	Belongs to the binding-protein-dependent transport system permease family
JGK51_RS05220	COG2814	Major facilitator Superfamily
JGK51_RS05225	COG0583	DNA-binding transcription factor activity
JGK51_RS05240	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
JGK51_RS05280	COG2205	protein histidine kinase activity
JGK51_RS05285	COG0745	RESPONSE REGULATOR receiver
JGK51_RS05290	COG1595	DNA-templated transcription, initiation
JGK51_RS05320	COG1012	belongs to the aldehyde dehydrogenase family
JGK51_RS05325	COG1012	belongs to the aldehyde dehydrogenase family
JGK51_RS05330	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JGK51_RS05340	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JGK51_RS05365	COG4770	biotin carboxylase activity
JGK51_RS05375	COG0424	maF-like protein
JGK51_RS05390	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JGK51_RS05405	COG2267	carboxylic ester hydrolase activity
JGK51_RS05415	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
JGK51_RS05425	COG1024	Enoyl-CoA hydratase
JGK51_RS05435	COG2986	histidine ammonia-lyase
JGK51_RS05465	COG1136	(ABC) transporter
JGK51_RS05475	COG1064	alcohol dehydrogenase
JGK51_RS05490	COG0501	Belongs to the peptidase M48B family
JGK51_RS05510	COG1595	DNA-templated transcription, initiation
JGK51_RS05520	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JGK51_RS05525	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JGK51_RS05535	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JGK51_RS05605	COG1331	Highly conserved protein containing a thioredoxin domain
JGK51_RS05625	COG1331	Highly conserved protein containing a thioredoxin domain
JGK51_RS05640	COG1309	transcriptional regulator
JGK51_RS05655	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
JGK51_RS05685	COG0436	Aminotransferase
JGK51_RS05700	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
JGK51_RS05715	COG1414	Transcriptional regulator
JGK51_RS05720	COG0251	oxidation-reduction process
JGK51_RS05760	COG2894	cell division
JGK51_RS05795	COG2197	response regulator
JGK51_RS05815	COG2885	chlorophyll binding
JGK51_RS05830	COG2226	methyltransferase
JGK51_RS05835	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JGK51_RS05840	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
JGK51_RS05855	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JGK51_RS05860	COG0450	alkyl hydroperoxide reductase
JGK51_RS05875	COG1136	(ABC) transporter
JGK51_RS05885	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JGK51_RS05900	COG0114	fumarate hydratase activity
JGK51_RS05905	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
JGK51_RS05905	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
JGK51_RS05930	COG0778	Nitroreductase
JGK51_RS05935	COG1722	exodeoxyribonuclease VII activity
JGK51_RS05940	COG1570	exodeoxyribonuclease VII activity
JGK51_RS05945	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
JGK51_RS05960	COG0012	GTP binding
JGK51_RS05965	COG4974	Belongs to the 'phage' integrase family
JGK51_RS06110	COG1053	succinate dehydrogenase
JGK51_RS06130	COG1217	gtp-binding protein TYPA
JGK51_RS06140	COG4166	transmembrane transport
JGK51_RS06145	COG0601	transmembrane transport
JGK51_RS06150	COG0444	Belongs to the ABC transporter superfamily
JGK51_RS06155	COG4608	Belongs to the ABC transporter superfamily
JGK51_RS06165	COG0346	lactoylglutathione lyase activity
JGK51_RS06170	COG4608	Belongs to the ABC transporter superfamily
JGK51_RS06175	COG0444	Belongs to the ABC transporter superfamily
JGK51_RS06185	COG0747	negative chemotaxis
JGK51_RS06190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JGK51_RS06195	COG4166	transmembrane transport
JGK51_RS06200	COG0601	transmembrane transport
JGK51_RS06205	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JGK51_RS06210	COG0444	Belongs to the ABC transporter superfamily
JGK51_RS06215	COG4608	Belongs to the ABC transporter superfamily
JGK51_RS06230	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JGK51_RS06245	COG1131	(ABC) transporter
JGK51_RS06255	COG4585	Histidine kinase
JGK51_RS06260	COG2197	response regulator
JGK51_RS06295	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JGK51_RS06300	COG1611	Belongs to the LOG family
JGK51_RS06305	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JGK51_RS06315	COG0519	Catalyzes the synthesis of GMP from XMP
JGK51_RS06320	COG1024	Enoyl-CoA hydratase
JGK51_RS06335	COG1595	DNA-templated transcription, initiation
JGK51_RS06345	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JGK51_RS06350	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JGK51_RS06385	COG0598	Magnesium transport protein CorA
JGK51_RS06395	COG2814	Major facilitator Superfamily
JGK51_RS06415	COG2095	MarC family integral membrane protein
JGK51_RS06425	COG1432	Conserved Protein
JGK51_RS06435	COG0513	Belongs to the DEAD box helicase family
JGK51_RS06485	COG0601	transmembrane transport
JGK51_RS06490	COG4172	Belongs to the ABC transporter superfamily
JGK51_RS06495	COG0438	transferase activity, transferring glycosyl groups
JGK51_RS06520	COG1846	Transcriptional regulator
JGK51_RS06550	COG0210	DNA helicase
JGK51_RS06560	COG2816	NAD+ diphosphatase activity
JGK51_RS06595	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JGK51_RS06600	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
JGK51_RS06655	COG3480	Lon protease (S16) C-terminal proteolytic domain
JGK51_RS06665	COG1615	UPF0182 protein
JGK51_RS06690	COG0753	catalase activity
JGK51_RS06700	COG0483	inositol monophosphate 1-phosphatase activity
JGK51_RS06715	COG2076	Multidrug Resistance protein
JGK51_RS06725	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
JGK51_RS06735	COG2135	peptidase activity
JGK51_RS06745	COG1595	DNA-templated transcription, initiation
JGK51_RS06750	COG5662	AntiSigma factor
JGK51_RS06760	COG0242	peptide deformylase activity
JGK51_RS06770	COG2124	cytochrome p450
JGK51_RS06775	COG4977	sequence-specific DNA binding
JGK51_RS06790	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JGK51_RS06790	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JGK51_RS06805	COG2188	Transcriptional regulator
JGK51_RS06810	COG0363	glucosamine-6-phosphate deaminase activity
JGK51_RS06825	COG1597	lipid kinase activity
JGK51_RS06840	COG2172	sigma factor antagonist activity
JGK51_RS06855	COG2515	1-aminocyclopropane-1-carboxylate deaminase
JGK51_RS06860	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JGK51_RS06865	COG0142	geranyltranstransferase activity
JGK51_RS06905	COG1335	isochorismatase
JGK51_RS06940	COG1309	transcriptional regulator
JGK51_RS06965	COG4106	trans-aconitate 2-methyltransferase activity
JGK51_RS06970	COG1126	abc transporter atp-binding protein
JGK51_RS06985	COG0281	malic enzyme
JGK51_RS06990	COG0604	alcohol dehydrogenase
JGK51_RS07010	COG0508	dehydrogenase complex catalyzes the overall conversion of
JGK51_RS07010	COG0567	Dehydrogenase, E1 component
JGK51_RS07015	COG2205	protein histidine kinase activity
JGK51_RS07020	COG0745	RESPONSE REGULATOR receiver
JGK51_RS07025	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
JGK51_RS07035	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
JGK51_RS07090	COG1309	transcriptional regulator
JGK51_RS07125	COG0768	penicillin binding
JGK51_RS07135	COG2205	protein histidine kinase activity
JGK51_RS07155	COG1793	dna ligase
JGK51_RS07155	COG3285	dna ligase
JGK51_RS07160	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
JGK51_RS07185	COG1028	Short-chain dehydrogenase reductase Sdr
JGK51_RS07190	COG4948	Mandelate Racemase Muconate Lactonizing
JGK51_RS07215	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JGK51_RS07225	COG0395	ABC-type sugar transport system, permease component
JGK51_RS07230	COG4209	transmembrane transport
JGK51_RS07235	COG1609	Transcriptional regulator
JGK51_RS07245	COG3903	Transcriptional regulator
JGK51_RS07245	COG3629	intracellular signal transduction
JGK51_RS07250	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JGK51_RS07280	COG1720	tRNA m6t6A37 methyltransferase activity
JGK51_RS07290	COG0626	cystathionine gamma-synthase activity
JGK51_RS07310	COG1720	tRNA m6t6A37 methyltransferase activity
JGK51_RS07315	COG4566	intracellular signal transduction
JGK51_RS07320	COG0436	Aminotransferase
JGK51_RS07350	COG0513	Belongs to the DEAD box helicase family
JGK51_RS07385	COG0018	arginyl-trna synthetase
JGK51_RS07390	COG0019	diaminopimelate decarboxylase activity
JGK51_RS07395	COG0460	homoserine dehydrogenase
JGK51_RS07400	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
JGK51_RS07405	COG0083	homoserine kinase activity
JGK51_RS07420	COG0254	rRNA binding
JGK51_RS07425	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JGK51_RS07430	COG2890	protein-(glutamine-N5) methyltransferase activity
JGK51_RS07440	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JGK51_RS07445	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JGK51_RS07450	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JGK51_RS07465	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JGK51_RS07470	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JGK51_RS07475	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JGK51_RS07480	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JGK51_RS07485	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JGK51_RS07490	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JGK51_RS07495	COG0355	proton-transporting ATP synthase activity, rotational mechanism
JGK51_RS07515	COG2197	response regulator
JGK51_RS07520	COG4585	Histidine kinase
JGK51_RS07550	COG1250	3-hydroxyacyl-CoA dehydrogenase
JGK51_RS07565	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
JGK51_RS07620	COG0183	Belongs to the thiolase family
JGK51_RS07685	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
JGK51_RS07685	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
JGK51_RS07720	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JGK51_RS07725	COG0280	phosphate acetyltransferase
JGK51_RS07725	COG0857	belongs to the CobB CobQ family
JGK51_RS07730	COG0205	6-phosphofructokinase activity
JGK51_RS07740	COG0395	ABC-type sugar transport system, permease component
JGK51_RS07745	COG1175	transmembrane transport
JGK51_RS07755	COG4565	transcriptional regulatory protein
JGK51_RS07760	COG3290	protein histidine kinase activity
JGK51_RS07765	COG1301	dicarboxylic acid transport
JGK51_RS07775	COG0477	Major facilitator Superfamily
JGK51_RS07795	COG3118	belongs to the thioredoxin family
JGK51_RS07805	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
JGK51_RS07820	COG0366	Alpha amylase catalytic
JGK51_RS07825	COG0058	SHG alpha-glucan phosphorylase activity
JGK51_RS07840	COG1132	(ABC) transporter
JGK51_RS07845	COG1132	(ABC) transporter
JGK51_RS07850	COG2197	response regulator
JGK51_RS07855	COG4585	Histidine kinase
JGK51_RS07865	COG1131	(ABC) transporter
JGK51_RS07870	COG1132	(ABC) transporter
JGK51_RS07875	COG1132	(ABC) transporter
JGK51_RS07915	COG1376	ErfK ybiS ycfS ynhG family protein
JGK51_RS07925	COG1024	Enoyl-CoA hydratase
JGK51_RS07970	COG1760	l-serine dehydratase
JGK51_RS07975	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JGK51_RS07980	COG0509	glycine decarboxylation via glycine cleavage system
JGK51_RS07985	COG0404	The glycine cleavage system catalyzes the degradation of glycine
JGK51_RS08005	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JGK51_RS08015	COG0601	transmembrane transport
JGK51_RS08025	COG4608	Belongs to the ABC transporter superfamily
JGK51_RS08035	COG2860	membrane
JGK51_RS08055	COG0583	DNA-binding transcription factor activity
JGK51_RS08100	COG0482	sulfurtransferase activity
JGK51_RS08115	COG1611	Belongs to the LOG family
JGK51_RS08120	COG4221	oxidoreductase activity
JGK51_RS08130	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JGK51_RS08150	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JGK51_RS08155	COG0154	amidase activity
JGK51_RS08165	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JGK51_RS08170	COG2409	Drug exporters of the RND superfamily
JGK51_RS08190	COG2197	response regulator
JGK51_RS08205	COG0667	Aldo Keto reductase
JGK51_RS08230	COG0440	acetolactate synthase activity
JGK51_RS08235	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
JGK51_RS08240	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JGK51_RS08245	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JGK51_RS08265	COG0596	Alpha beta hydrolase
JGK51_RS08270	COG3835	regulator
JGK51_RS08280	COG1012	belongs to the aldehyde dehydrogenase family
JGK51_RS08290	COG2130	NADP-dependent
JGK51_RS08300	COG0473	3-isopropylmalate dehydrogenase activity
JGK51_RS08305	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JGK51_RS08315	COG0804	urea catabolic process
JGK51_RS08320	COG2957	Belongs to the agmatine deiminase family
JGK51_RS08340	COG0477	Major facilitator Superfamily
JGK51_RS08345	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JGK51_RS08365	COG1472	Belongs to the glycosyl hydrolase 3 family
JGK51_RS08385	COG2353	YceI-like domain
JGK51_RS08390	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JGK51_RS08410	COG2018	Roadblock/LC7 domain
JGK51_RS08430	COG2018	Roadblock/LC7 domain
JGK51_RS08435	COG5002	protein histidine kinase activity
JGK51_RS08445	COG0179	Fumarylacetoacetate (FAA) hydrolase
JGK51_RS08450	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JGK51_RS08495	COG1414	Transcriptional regulator
JGK51_RS08500	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JGK51_RS08505	COG0066	3-isopropylmalate dehydratase activity
JGK51_RS08515	COG0776	regulation of translation
JGK51_RS08525	COG1920	GTP binding
JGK51_RS08535	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
JGK51_RS08540	COG1181	Belongs to the D-alanine--D-alanine ligase family
JGK51_RS08560	COG0351	phosphomethylpyrimidine kinase
JGK51_RS08575	COG0227	Belongs to the bacterial ribosomal protein bL28 family
JGK51_RS08580	COG1461	Dihydroxyacetone kinase
JGK51_RS08590	COG0326	Molecular chaperone. Has ATPase activity
JGK51_RS08600	COG0742	ribosomal rna small subunit methyltransferase
JGK51_RS08605	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JGK51_RS08620	COG0333	Belongs to the bacterial ribosomal protein bL32 family
JGK51_RS08625	COG0571	ribonuclease III activity
JGK51_RS08630	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JGK51_RS08635	COG1733	regulation of RNA biosynthetic process
JGK51_RS08650	COG1254	Belongs to the acylphosphatase family
JGK51_RS08665	COG0477	Major facilitator Superfamily
JGK51_RS08710	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
JGK51_RS08720	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JGK51_RS08735	COG0228	four-way junction DNA binding
JGK51_RS08740	COG1837	Belongs to the UPF0109 family
JGK51_RS08745	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JGK51_RS08750	COG0336	Belongs to the RNA methyltransferase TrmD family
JGK51_RS08755	COG0335	large ribosomal subunit rRNA binding
JGK51_RS08770	COG0681	Belongs to the peptidase S26 family
JGK51_RS08790	COG0792	nuclease activity
JGK51_RS08805	COG1191	sigma factor activity
JGK51_RS08815	COG4942	peptidase
JGK51_RS08820	COG0052	Belongs to the universal ribosomal protein uS2 family
JGK51_RS08825	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JGK51_RS08830	COG0528	UMP kinase activity
JGK51_RS08835	COG0233	cytoplasmic translational termination
JGK51_RS08840	COG0575	Belongs to the CDS family
JGK51_RS08850	COG0820	rRNA (adenine-C2-)-methyltransferase activity
JGK51_RS08860	COG4208	sulfate ABC transporter
JGK51_RS08865	COG3842	ATPase activity
JGK51_RS08885	COG4181	ATPase activity
JGK51_RS08890	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JGK51_RS08900	COG1012	belongs to the aldehyde dehydrogenase family
JGK51_RS08910	COG0395	ABC-type sugar transport system, permease component
JGK51_RS08915	COG1175	transmembrane transport
JGK51_RS08940	COG0584	glycerophosphoryl diester phosphodiesterase
JGK51_RS08945	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
JGK51_RS08960	COG1012	belongs to the aldehyde dehydrogenase family
JGK51_RS08970	COG3842	ATPase activity
JGK51_RS08975	COG1176	ABC-type spermidine putrescine transport system, permease component I
JGK51_RS08980	COG1177	transmembrane transport
JGK51_RS08985	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JGK51_RS09015	COG2508	Transcriptional regulator
JGK51_RS09020	COG1012	belongs to the aldehyde dehydrogenase family
JGK51_RS09040	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
JGK51_RS09045	COG0750	zinc metalloprotease
JGK51_RS09050	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
JGK51_RS09075	COG3210	domain, Protein
JGK51_RS09090	COG1247	-acetyltransferase
JGK51_RS09095	COG0442	prolyl-tRNA aminoacylation
JGK51_RS09115	COG0779	Required for maturation of 30S ribosomal subunits
JGK51_RS09130	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JGK51_RS09140	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JGK51_RS09145	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JGK51_RS09160	COG0455	bacterial-type flagellum organization
JGK51_RS09195	COG1404	Belongs to the peptidase S8 family
JGK51_RS09225	COG1674	ftsk spoiiie
JGK51_RS09245	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
JGK51_RS09250	COG1185	polyribonucleotide nucleotidyltransferase activity
JGK51_RS09255	COG0612	Peptidase, M16
JGK51_RS09260	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JGK51_RS09280	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
JGK51_RS09285	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JGK51_RS09290	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JGK51_RS09320	COG2770	Histidine kinase
JGK51_RS09320	COG2208	phosphoserine phosphatase activity
JGK51_RS09325	COG0784	Response regulator, receiver
JGK51_RS09325	COG2205	protein histidine kinase activity
JGK51_RS09335	COG1674	ftsk spoiiie
JGK51_RS09345	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JGK51_RS09355	COG1058	Belongs to the CinA family
JGK51_RS09355	COG1546	Belongs to the CinA family
JGK51_RS09360	COG1396	sequence-specific DNA binding
JGK51_RS09365	COG0783	Belongs to the Dps family
JGK51_RS09375	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JGK51_RS09380	COG1201	RNA secondary structure unwinding
JGK51_RS09405	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JGK51_RS09410	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JGK51_RS09415	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JGK51_RS09460	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JGK51_RS09470	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JGK51_RS09485	COG0765	amino acid transport
JGK51_RS09490	COG0765	amino acid transport
JGK51_RS09495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JGK51_RS09500	COG1126	abc transporter atp-binding protein
JGK51_RS09505	COG0745	RESPONSE REGULATOR receiver
JGK51_RS09510	COG2205	protein histidine kinase activity
JGK51_RS09550	COG1280	lysine exporter protein (LysE YggA)
JGK51_RS09565	COG3433	isochorismatase activity
JGK51_RS09565	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JGK51_RS09565	COG2226	methyltransferase
JGK51_RS09570	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JGK51_RS09590	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JGK51_RS09600	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
JGK51_RS09605	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JGK51_RS09615	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JGK51_RS09645	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JGK51_RS09650	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JGK51_RS09655	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JGK51_RS09675	COG0588	phosphoglycerate mutase activity
JGK51_RS09700	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JGK51_RS09735	COG2186	Transcriptional regulator
JGK51_RS09740	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JGK51_RS09755	COG0187	DNA topoisomerase II activity
JGK51_RS09760	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JGK51_RS09780	COG2197	response regulator
JGK51_RS09790	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JGK51_RS09795	COG4565	transcriptional regulatory protein
JGK51_RS09805	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JGK51_RS09815	COG3290	protein histidine kinase activity
JGK51_RS09830	COG0372	Belongs to the citrate synthase family
JGK51_RS09850	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JGK51_RS09855	COG0612	Peptidase, M16
JGK51_RS09870	COG1802	Transcriptional regulator
JGK51_RS09875	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JGK51_RS09900	COG1435	thymidine kinase activity
JGK51_RS09935	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
JGK51_RS09950	COG0745	RESPONSE REGULATOR receiver
JGK51_RS09955	COG2205	protein histidine kinase activity
JGK51_RS09980	COG0756	dUTP diphosphatase activity
JGK51_RS10015	COG0569	domain protein
JGK51_RS10020	COG0531	amino acid
JGK51_RS10025	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JGK51_RS10080	COG0596	Alpha beta hydrolase
JGK51_RS10085	COG2175	clavaminate synthase activity
JGK51_RS10090	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JGK51_RS10095	COG1657	PFAM Prenyltransferase squalene oxidase
JGK51_RS10105	COG0179	Fumarylacetoacetate (FAA) hydrolase
JGK51_RS10120	COG2124	cytochrome p450
JGK51_RS10135	COG1960	acyl-CoA dehydrogenase activity
JGK51_RS10140	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JGK51_RS10150	COG0142	geranyltranstransferase activity
JGK51_RS10155	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
JGK51_RS10165	COG1028	Short-chain dehydrogenase reductase Sdr
JGK51_RS10190	COG1819	glycosyl
JGK51_RS10240	COG3629	intracellular signal transduction
JGK51_RS10240	COG3903	Transcriptional regulator
JGK51_RS10315	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JGK51_RS10330	COG1846	Transcriptional regulator
JGK51_RS10405	COG1799	cell septum assembly
JGK51_RS10435	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
JGK51_RS10455	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JGK51_RS10460	COG0531	amino acid
JGK51_RS10470	COG1024	Enoyl-CoA hydratase
JGK51_RS10560	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JGK51_RS10565	COG3629	intracellular signal transduction
JGK51_RS10585	COG2814	Major facilitator Superfamily
JGK51_RS10590	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
JGK51_RS10595	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
JGK51_RS10600	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JGK51_RS10610	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JGK51_RS10615	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JGK51_RS10620	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JGK51_RS10645	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JGK51_RS10655	COG1012	belongs to the aldehyde dehydrogenase family
JGK51_RS10670	COG0318	PFAM AMP-dependent synthetase and ligase
JGK51_RS10685	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JGK51_RS10690	COG0477	Major facilitator Superfamily
JGK51_RS10695	COG0477	Major facilitator Superfamily
JGK51_RS10705	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JGK51_RS10720	COG2188	Transcriptional regulator
JGK51_RS10725	COG2182	Extracellular solute-binding protein
JGK51_RS10730	COG1175	transmembrane transport
JGK51_RS10735	COG0395	ABC-type sugar transport system, permease component
JGK51_RS10740	COG1472	Belongs to the glycosyl hydrolase 3 family
JGK51_RS10790	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JGK51_RS10795	COG1522	sequence-specific DNA binding
JGK51_RS10810	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JGK51_RS10815	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
JGK51_RS10855	COG4195	phage-related replication protein
JGK51_RS10885	COG1653	transport
JGK51_RS10890	COG1175	transmembrane transport
JGK51_RS10895	COG0395	ABC-type sugar transport system, permease component
JGK51_RS10900	COG1940	carbohydrate kinase activity
JGK51_RS10905	COG4213	ABC transporter substrate-binding protein
JGK51_RS10915	COG4214	carbohydrate transport
JGK51_RS10920	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
JGK51_RS10925	COG0531	amino acid
JGK51_RS10950	COG1024	Enoyl-CoA hydratase
JGK51_RS10950	COG1250	3-hydroxyacyl-CoA dehydrogenase
JGK51_RS10955	COG0183	Belongs to the thiolase family
JGK51_RS10960	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
JGK51_RS10975	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
JGK51_RS10985	COG0446	pyridine nucleotide-disulphide oxidoreductase
JGK51_RS10995	COG3253	May function as heme-dependent peroxidase
JGK51_RS11010	COG3220	belongs to the UPF0276 family
JGK51_RS11025	COG4152	abc transporter atp-binding protein
JGK51_RS11040	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JGK51_RS11040	COG0723	plastoquinol--plastocyanin reductase activity
JGK51_RS11045	COG2326	polyphosphate kinase activity
JGK51_RS11080	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JGK51_RS11085	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JGK51_RS11095	COG1174	glycine betaine transport
JGK51_RS11100	COG1174	glycine betaine transport
JGK51_RS11140	COG2124	cytochrome p450
JGK51_RS11160	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JGK51_RS11195	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JGK51_RS11200	COG0583	DNA-binding transcription factor activity
JGK51_RS11235	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JGK51_RS11255	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JGK51_RS11255	COG1116	anion transmembrane transporter activity
JGK51_RS11280	COG0529	Catalyzes the synthesis of activated sulfate
JGK51_RS11285	COG0175	sulfate reduction
JGK51_RS11295	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JGK51_RS11315	COG1960	acyl-CoA dehydrogenase activity
JGK51_RS11340	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
JGK51_RS11355	COG2040	homocysteine
JGK51_RS11375	COG0277	FAD linked oxidase domain protein
JGK51_RS11395	COG1942	4-Oxalocrotonate Tautomerase
JGK51_RS11400	COG2814	Major facilitator Superfamily
JGK51_RS11405	COG0583	DNA-binding transcription factor activity
JGK51_RS11420	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
JGK51_RS11420	COG0473	3-isopropylmalate dehydrogenase activity
JGK51_RS11430	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JGK51_RS11440	COG1162	GTPase activity
JGK51_RS11465	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JGK51_RS11475	COG2267	carboxylic ester hydrolase activity
JGK51_RS11500	COG0028	Belongs to the TPP enzyme family
JGK51_RS11515	COG1802	Transcriptional regulator
JGK51_RS11545	COG1529	Aldehyde oxidase and xanthine dehydrogenase
JGK51_RS11550	COG2252	PERMEase
JGK51_RS11560	COG1280	lysine exporter protein (LysE YggA)
JGK51_RS11570	COG0726	polysaccharide deacetylase
JGK51_RS11580	COG0515	serine threonine protein kinase
JGK51_RS11595	COG1653	transport
JGK51_RS11610	COG2249	NAD(P)H dehydrogenase (quinone) activity
JGK51_RS11625	COG2197	response regulator
JGK51_RS11630	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JGK51_RS11635	COG0318	PFAM AMP-dependent synthetase and ligase
JGK51_RS11645	COG3960	tartronate-semialdehyde synthase activity
JGK51_RS11660	COG0753	catalase activity
JGK51_RS11665	COG2084	Dehydrogenase
JGK51_RS11670	COG3622	Belongs to the hyi family
JGK51_RS11690	COG2351	hydroxyisourate hydrolase activity
JGK51_RS11705	COG2233	PERMEase
JGK51_RS11735	COG0406	alpha-ribazole phosphatase activity
JGK51_RS11755	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JGK51_RS11770	COG4555	ABC transporter
JGK51_RS11785	COG1181	Belongs to the D-alanine--D-alanine ligase family
JGK51_RS11790	COG2368	4-hydroxyphenylacetate
JGK51_RS11815	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JGK51_RS11820	COG1454	alcohol dehydrogenase
JGK51_RS11835	COG0367	asparagine synthase
JGK51_RS11855	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JGK51_RS11870	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JGK51_RS11875	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
JGK51_RS11895	COG1012	belongs to the aldehyde dehydrogenase family
JGK51_RS11900	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
JGK51_RS11910	COG0436	Aminotransferase
JGK51_RS11915	COG1733	regulation of RNA biosynthetic process
JGK51_RS11960	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JGK51_RS11975	COG0384	phenazine biosynthesis protein PhzF
JGK51_RS12010	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JGK51_RS12030	COG0017	Asparaginyl-tRNA synthetase
JGK51_RS12040	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JGK51_RS12045	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JGK51_RS12055	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JGK51_RS12085	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
JGK51_RS12090	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JGK51_RS12105	COG1414	Transcriptional regulator
JGK51_RS12110	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JGK51_RS12115	COG4266	Belongs to the allantoicase family
JGK51_RS12150	COG0673	inositol 2-dehydrogenase activity
JGK51_RS12155	COG2188	Transcriptional regulator
JGK51_RS12175	COG1940	carbohydrate kinase activity
JGK51_RS12185	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JGK51_RS12200	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JGK51_RS12205	COG0583	DNA-binding transcription factor activity
JGK51_RS12210	COG0069	glutamate synthase activity
JGK51_RS12215	COG0017	Asparaginyl-tRNA synthetase
JGK51_RS12220	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JGK51_RS12235	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JGK51_RS12305	COG3842	ATPase activity
JGK51_RS12310	COG1725	Transcriptional regulator
JGK51_RS12315	COG1271	oxidase subunit
JGK51_RS12320	COG1294	oxidase, subunit
JGK51_RS12330	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JGK51_RS12335	COG4569	acetaldehyde dehydrogenase (acetylating) activity
JGK51_RS12350	COG0346	lactoylglutathione lyase activity
JGK51_RS12360	COG1309	transcriptional regulator
JGK51_RS12365	COG1414	Transcriptional regulator
JGK51_RS12385	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JGK51_RS12400	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JGK51_RS12425	COG0405	Gamma-glutamyltransferase
JGK51_RS12430	COG0542	response to heat
JGK51_RS12465	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JGK51_RS12475	COG1953	Uracil, thiamine, allantoin
JGK51_RS12535	COG0542	response to heat
JGK51_RS12570	COG0095	Lipoate-protein ligase
JGK51_RS12585	COG0531	amino acid
JGK51_RS12595	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
JGK51_RS12600	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
JGK51_RS12605	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
JGK51_RS12645	COG0318	PFAM AMP-dependent synthetase and ligase
JGK51_RS12700	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
JGK51_RS12715	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
JGK51_RS12730	COG1929	Belongs to the glycerate kinase type-1 family
JGK51_RS12740	COG0688	phosphatidylethanolamine metabolic process
JGK51_RS12755	COG2301	Belongs to the HpcH HpaI aldolase family
JGK51_RS12760	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
JGK51_RS12760	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
JGK51_RS12765	COG0604	alcohol dehydrogenase
JGK51_RS12775	COG1250	3-hydroxyacyl-CoA dehydrogenase
JGK51_RS12790	COG1295	ribonuclease BN
JGK51_RS12820	COG1366	Belongs to the anti-sigma-factor antagonist family
JGK51_RS12820	COG2208	phosphoserine phosphatase activity
JGK51_RS12820	COG2172	sigma factor antagonist activity
JGK51_RS12825	COG4106	trans-aconitate 2-methyltransferase activity
JGK51_RS12835	COG0038	chloride channel
JGK51_RS12840	COG2362	D-Aminopeptidase
JGK51_RS12845	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JGK51_RS12855	COG1619	proteins homologs of microcin C7 resistance protein MccF
JGK51_RS12880	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JGK51_RS12885	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JGK51_RS12890	COG1793	dna ligase
JGK51_RS12890	COG3285	dna ligase
JGK51_RS12945	COG2226	methyltransferase
JGK51_RS12950	COG1597	lipid kinase activity
JGK51_RS12955	COG0406	alpha-ribazole phosphatase activity
JGK51_RS12960	COG0488	(ABC) transporter
JGK51_RS12970	COG0693	protein deglycase activity
JGK51_RS12985	COG0028	Belongs to the TPP enzyme family
JGK51_RS13010	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JGK51_RS13040	COG2154	pterin-4-alpha-carbinolamine dehydratase
JGK51_RS13045	COG2226	methyltransferase
JGK51_RS13060	COG4221	oxidoreductase activity
JGK51_RS13075	COG0656	L-ascorbic acid biosynthetic process
JGK51_RS13105	COG1846	Transcriptional regulator
JGK51_RS13110	COG1028	Short-chain dehydrogenase reductase Sdr
JGK51_RS13115	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
JGK51_RS13120	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JGK51_RS13265	COG3537	Alpha-1,2-mannosidase
JGK51_RS13275	COG1335	isochorismatase
JGK51_RS13295	COG0326	Molecular chaperone. Has ATPase activity
JGK51_RS13335	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JGK51_RS13345	COG3251	PFAM MbtH domain protein
JGK51_RS13350	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JGK51_RS13400	COG0569	domain protein
JGK51_RS13400	COG0475	glutathione-regulated potassium exporter activity
JGK51_RS13415	COG2423	ornithine cyclodeaminase activity
JGK51_RS13420	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JGK51_RS13425	COG4569	acetaldehyde dehydrogenase (acetylating) activity
JGK51_RS13435	COG0156	8-amino-7-oxononanoate synthase activity
JGK51_RS13450	COG0006	proline dipeptidase activity
JGK51_RS13455	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JGK51_RS13505	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
JGK51_RS13505	COG0028	Belongs to the TPP enzyme family
JGK51_RS13530	COG4106	trans-aconitate 2-methyltransferase activity
JGK51_RS13545	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JGK51_RS13580	COG2182	Extracellular solute-binding protein
JGK51_RS13585	COG1175	transmembrane transport
JGK51_RS13590	COG0395	ABC-type sugar transport system, permease component
JGK51_RS13595	COG2723	6-phospho-beta-galactosidase activity
JGK51_RS13620	COG3467	pyridoxamine 5'-phosphate
JGK51_RS13625	COG2084	Dehydrogenase
JGK51_RS13640	COG0588	phosphoglycerate mutase activity
JGK51_RS13645	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
JGK51_RS13650	COG0166	Belongs to the GPI family
JGK51_RS13665	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JGK51_RS13680	COG0667	Aldo Keto reductase
JGK51_RS13685	COG0789	Transcriptional regulator
JGK51_RS13705	COG1486	melibiose metabolic process
JGK51_RS13710	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
JGK51_RS13735	COG3511	phospholipase C
JGK51_RS13765	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
JGK51_RS13770	COG0477	Major facilitator Superfamily
JGK51_RS13790	COG1793	dna ligase
JGK51_RS13825	COG1834	amidinotransferase
JGK51_RS13840	COG0488	(ABC) transporter
JGK51_RS13870	COG1515	deoxyribonuclease V activity
JGK51_RS13880	COG3268	Saccharopine dehydrogenase
JGK51_RS13885	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JGK51_RS13890	COG0183	Belongs to the thiolase family
JGK51_RS13895	COG1024	Enoyl-CoA hydratase
JGK51_RS13895	COG1250	3-hydroxyacyl-CoA dehydrogenase
JGK51_RS13905	COG1113	amino acid transport
JGK51_RS13920	COG0745	RESPONSE REGULATOR receiver
JGK51_RS13925	COG0243	molybdopterin cofactor binding
JGK51_RS13930	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JGK51_RS13935	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JGK51_RS13935	COG2146	nitrite reductase [NAD(P)H] activity
JGK51_RS13940	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JGK51_RS13940	COG2146	nitrite reductase [NAD(P)H] activity
JGK51_RS13945	COG2223	nitrite transmembrane transporter activity
JGK51_RS13955	COG2936	dipeptidyl-peptidase activity
JGK51_RS13965	COG0488	(ABC) transporter
JGK51_RS13975	COG2183	response to ionizing radiation
JGK51_RS13980	COG4977	sequence-specific DNA binding
JGK51_RS13995	COG1024	Enoyl-CoA hydratase
JGK51_RS14010	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
JGK51_RS14055	COG1134	teichoic acid transport
JGK51_RS14060	COG1562	ergosterol biosynthetic process
JGK51_RS14070	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
JGK51_RS14080	COG1657	PFAM Prenyltransferase squalene oxidase
JGK51_RS14095	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
JGK51_RS14100	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
JGK51_RS14125	COG2365	Tyrosine phosphatase family
JGK51_RS14135	COG2755	lipolytic protein G-D-S-L family
JGK51_RS14175	COG1131	(ABC) transporter
JGK51_RS14180	COG0842	Transport permease protein
JGK51_RS14195	COG1473	amidohydrolase
JGK51_RS14250	COG1063	alcohol dehydrogenase
JGK51_RS14255	COG0156	8-amino-7-oxononanoate synthase activity
JGK51_RS14260	COG0583	DNA-binding transcription factor activity
JGK51_RS14275	COG3958	Transketolase
JGK51_RS14280	COG3959	Transketolase, thiamine diphosphate binding domain
JGK51_RS14310	COG1028	Short-chain dehydrogenase reductase Sdr
JGK51_RS14320	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
JGK51_RS14345	COG3903	Transcriptional regulator
JGK51_RS14345	COG3629	intracellular signal transduction
JGK51_RS14405	COG0174	glutamine synthetase
JGK51_RS14415	COG0561	phosphatase activity
JGK51_RS14440	COG2267	carboxylic ester hydrolase activity
JGK51_RS14445	COG0183	Belongs to the thiolase family
JGK51_RS14450	COG0318	PFAM AMP-dependent synthetase and ligase
JGK51_RS14460	COG0667	Aldo Keto reductase
JGK51_RS14505	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JGK51_RS14535	COG2124	cytochrome p450
JGK51_RS14570	COG0673	inositol 2-dehydrogenase activity
JGK51_RS14610	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JGK51_RS14625	COG4221	oxidoreductase activity
JGK51_RS14665	COG0154	amidase activity
JGK51_RS14670	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JGK51_RS14675	COG1584	GPR1 FUN34 yaaH family protein
JGK51_RS14680	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JGK51_RS14695	COG3275	phosphorelay sensor kinase activity
JGK51_RS14700	COG1136	(ABC) transporter
JGK51_RS14700	COG0577	efflux transmembrane transporter activity
JGK51_RS14710	COG4585	Histidine kinase
JGK51_RS14715	COG2197	response regulator
JGK51_RS14720	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JGK51_RS14725	COG0702	epimerase
JGK51_RS14735	COG0531	amino acid
JGK51_RS14740	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
JGK51_RS14770	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JGK51_RS14775	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JGK51_RS14785	COG2197	response regulator
JGK51_RS14810	COG2124	cytochrome p450
JGK51_RS14820	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JGK51_RS14835	COG2838	Isocitrate dehydrogenase
JGK51_RS14845	COG0668	transmembrane transport
JGK51_RS14850	COG0531	amino acid
JGK51_RS14860	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JGK51_RS14865	COG0579	oxidoreductase
JGK51_RS14880	COG1024	Enoyl-CoA hydratase
JGK51_RS14890	COG1132	(ABC) transporter
JGK51_RS14895	COG2080	2 iron, 2 sulfur cluster binding
JGK51_RS14900	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
JGK51_RS14905	COG1529	Aldehyde oxidase and xanthine dehydrogenase
JGK51_RS14975	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
JGK51_RS15010	COG2079	MmgE PrpD family protein
JGK51_RS15015	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
JGK51_RS15030	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JGK51_RS15045	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
JGK51_RS15045	COG5479	isomerase activity
JGK51_RS15050	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JGK51_RS15060	COG1028	Short-chain dehydrogenase reductase Sdr
JGK51_RS15060	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JGK51_RS15060	COG3321	synthase
JGK51_RS15060	COG4221	oxidoreductase activity
JGK51_RS15110	COG0559	Belongs to the binding-protein-dependent transport system permease family
JGK51_RS15145	COG3903	Transcriptional regulator
JGK51_RS15145	COG3629	intracellular signal transduction
JGK51_RS15190	COG0513	Belongs to the DEAD box helicase family
JGK51_RS15195	COG1278	Cold shock
JGK51_RS15230	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JGK51_RS15235	COG0523	cobalamin synthesis protein
JGK51_RS15245	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JGK51_RS15255	COG0254	rRNA binding
JGK51_RS15260	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JGK51_RS15265	COG0227	Belongs to the bacterial ribosomal protein bL28 family
JGK51_RS15270	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JGK51_RS15345	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
JGK51_RS15345	COG2308	Evidence 4 Homologs of previously reported genes of
JGK51_RS15380	COG1028	Short-chain dehydrogenase reductase Sdr
JGK51_RS15390	COG0601	transmembrane transport
JGK51_RS15415	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JGK51_RS15420	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
JGK51_RS15425	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
JGK51_RS15445	COG3537	Alpha-1,2-mannosidase
JGK51_RS15480	COG0154	amidase activity
JGK51_RS15505	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JGK51_RS15520	COG0531	amino acid
JGK51_RS15540	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
JGK51_RS15540	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
JGK51_RS15580	COG0583	DNA-binding transcription factor activity
JGK51_RS15590	COG1053	succinate dehydrogenase
JGK51_RS15595	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JGK51_RS15620	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JGK51_RS15630	COG3360	Dodecin
JGK51_RS15635	COG2182	Extracellular solute-binding protein
JGK51_RS15640	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
JGK51_RS15645	COG0121	glutamine amidotransferase
JGK51_RS15650	COG1262	PFAM Formylglycine-generating sulfatase enzyme
JGK51_RS15705	COG1609	Transcriptional regulator
JGK51_RS15710	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JGK51_RS15720	COG0242	peptide deformylase activity
JGK51_RS15735	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
JGK51_RS15735	COG3608	succinylglutamate desuccinylase aspartoacylase
JGK51_RS15755	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
JGK51_RS15755	COG3608	succinylglutamate desuccinylase aspartoacylase
JGK51_RS15760	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
JGK51_RS15790	COG3261	NADH dehydrogenase
JGK51_RS15790	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
JGK51_RS15795	COG0651	ATP synthesis coupled electron transport
JGK51_RS15805	COG0650	Formate hydrogenlyase subunit 4
JGK51_RS15815	COG3260	NADH ubiquinone oxidoreductase 20
JGK51_RS15825	COG2824	Alkylphosphonate utilization operon protein PhnA
JGK51_RS15840	COG0659	secondary active sulfate transmembrane transporter activity
JGK51_RS15850	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JGK51_RS15860	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JGK51_RS15865	COG1993	acr, cog1993
JGK51_RS15870	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JGK51_RS15875	COG0326	Molecular chaperone. Has ATPase activity
JGK51_RS15925	COG2124	cytochrome p450
JGK51_RS15950	COG2197	response regulator
JGK51_RS15955	COG2197	response regulator
JGK51_RS15960	COG3340	Belongs to the peptidase S51 family
JGK51_RS15970	COG3251	PFAM MbtH domain protein
JGK51_RS15980	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JGK51_RS15985	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JGK51_RS16015	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JGK51_RS16020	COG1233	COG1233 Phytoene dehydrogenase and related
JGK51_RS16025	COG0726	polysaccharide deacetylase
JGK51_RS16040	COG1609	Transcriptional regulator
JGK51_RS16060	COG1028	Short-chain dehydrogenase reductase Sdr
JGK51_RS16065	COG0515	serine threonine protein kinase
JGK51_RS16065	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JGK51_RS16070	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JGK51_RS16075	COG1250	3-hydroxyacyl-CoA dehydrogenase
JGK51_RS16095	COG0148	phosphopyruvate hydratase activity
JGK51_RS16100	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
JGK51_RS16165	COG0640	Transcriptional regulator
JGK51_RS16215	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
JGK51_RS16220	COG1028	Short-chain dehydrogenase reductase Sdr
JGK51_RS16225	COG1021	2,3-dihydroxybenzoate-AMP ligase
JGK51_RS16230	COG1535	isochorismatase
JGK51_RS16230	COG3433	isochorismatase activity
JGK51_RS16235	COG3486	L-lysine 6-monooxygenase (NADPH) activity
JGK51_RS16245	COG1169	isochorismate synthase
JGK51_RS16250	COG3433	isochorismatase activity
JGK51_RS16250	COG1535	isochorismatase
JGK51_RS16265	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JGK51_RS16270	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JGK51_RS16275	COG1120	ATPase activity
JGK51_RS16285	COG0477	Major facilitator Superfamily
JGK51_RS16310	COG0778	Nitroreductase
JGK51_RS16330	COG1191	sigma factor activity
JGK51_RS16350	COG0542	response to heat
JGK51_RS16355	COG1174	glycine betaine transport
JGK51_RS16375	COG1556	Lactate utilization protein
JGK51_RS16380	COG1139	Iron-sulfur cluster binding protein
JGK51_RS16385	COG0247	lactate metabolic process
JGK51_RS16400	COG1357	PFAM Pentapeptide repeats (8 copies)
JGK51_RS16410	COG1309	transcriptional regulator
JGK51_RS16420	COG1032	radical SAM domain protein
JGK51_RS16425	COG0318	PFAM AMP-dependent synthetase and ligase
JGK51_RS16435	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JGK51_RS16455	COG2706	6-phosphogluconolactonase activity
JGK51_RS16475	COG1940	carbohydrate kinase activity
JGK51_RS16475	COG1846	Transcriptional regulator
JGK51_RS16495	COG2267	carboxylic ester hydrolase activity
JGK51_RS16500	COG0546	phosphoglycolate phosphatase activity
JGK51_RS16505	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JGK51_RS16505	COG1796	DNA polymerase
JGK51_RS16535	COG2111	Na H antiporter
JGK51_RS16545	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JGK51_RS16550	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
JGK51_RS16555	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JGK51_RS16585	COG0435	Glutathione S-transferase
JGK51_RS16605	COG2124	cytochrome p450
JGK51_RS16645	COG0657	acetylesterase activity
JGK51_RS16655	COG3629	intracellular signal transduction
JGK51_RS16660	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JGK51_RS16665	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
JGK51_RS16690	COG0667	Aldo Keto reductase
JGK51_RS16720	COG1595	DNA-templated transcription, initiation
JGK51_RS16750	COG1012	belongs to the aldehyde dehydrogenase family
JGK51_RS16810	COG0366	Alpha amylase catalytic
JGK51_RS16815	COG3281	Trehalose synthase
JGK51_RS16820	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
JGK51_RS16840	COG0297	glycogen (starch) synthase activity
JGK51_RS16880	COG0702	epimerase
JGK51_RS16885	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JGK51_RS16905	COG0483	inositol monophosphate 1-phosphatase activity
JGK51_RS16920	COG2197	response regulator
JGK51_RS16925	COG4585	Histidine kinase
JGK51_RS16940	COG0596	Alpha beta hydrolase
JGK51_RS16955	COG2890	protein-(glutamine-N5) methyltransferase activity
JGK51_RS16975	COG4221	oxidoreductase activity
JGK51_RS17005	COG2274	protein secretion by the type I secretion system
JGK51_RS17055	COG0247	lactate metabolic process
JGK51_RS17055	COG0277	FAD linked oxidase domain protein
JGK51_RS17060	COG4948	Mandelate Racemase Muconate Lactonizing
JGK51_RS17065	COG0300	oxidoreductase activity
JGK51_RS17110	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JGK51_RS17145	COG1028	Short-chain dehydrogenase reductase Sdr
JGK51_RS17155	COG0583	DNA-binding transcription factor activity
JGK51_RS17185	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
JGK51_RS17205	COG1309	transcriptional regulator
JGK51_RS17210	COG1609	Transcriptional regulator
JGK51_RS17265	COG0572	uridine kinase
JGK51_RS17295	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
JGK51_RS17310	COG1335	isochorismatase
JGK51_RS17315	COG2814	Major facilitator Superfamily
JGK51_RS17325	COG0671	phosphoesterase, PA-phosphatase related
JGK51_RS17330	COG0586	Pfam SNARE associated Golgi protein
JGK51_RS17345	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
JGK51_RS17360	COG3387	PFAM Glycoside hydrolase 15-related
JGK51_RS17370	COG0583	DNA-binding transcription factor activity
JGK51_RS17385	COG0590	tRNA wobble adenosine to inosine editing
JGK51_RS17390	COG1366	Belongs to the anti-sigma-factor antagonist family
JGK51_RS17390	COG2172	sigma factor antagonist activity
JGK51_RS17390	COG2208	phosphoserine phosphatase activity
JGK51_RS17440	COG0726	polysaccharide deacetylase
JGK51_RS17470	COG4585	Histidine kinase
JGK51_RS17475	COG2197	response regulator
JGK51_RS17525	COG1028	Short-chain dehydrogenase reductase Sdr
JGK51_RS17535	COG0156	8-amino-7-oxononanoate synthase activity
JGK51_RS17545	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JGK51_RS17555	COG0318	PFAM AMP-dependent synthetase and ligase
JGK51_RS17560	COG2814	Major facilitator Superfamily
JGK51_RS17570	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
JGK51_RS17580	COG3469	chitinase activity
JGK51_RS17650	COG2172	sigma factor antagonist activity
JGK51_RS17655	COG1366	Belongs to the anti-sigma-factor antagonist family
JGK51_RS17660	COG1366	Belongs to the anti-sigma-factor antagonist family
JGK51_RS17685	COG2814	Major facilitator Superfamily
JGK51_RS17690	COG1846	Transcriptional regulator
JGK51_RS17710	COG1309	transcriptional regulator
JGK51_RS17725	COG1028	Short-chain dehydrogenase reductase Sdr
JGK51_RS17735	COG1028	Short-chain dehydrogenase reductase Sdr
JGK51_RS17750	COG0477	Major facilitator Superfamily
JGK51_RS17760	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
JGK51_RS17765	COG5297	Belongs to the glycosyl hydrolase family 6
JGK51_RS17770	COG5297	Belongs to the glycosyl hydrolase family 6
JGK51_RS17770	COG4733	cellulase activity
JGK51_RS17775	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
JGK51_RS17785	COG1937	Protein conserved in bacteria
JGK51_RS17795	COG0730	response to heat
JGK51_RS17805	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JGK51_RS17805	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JGK51_RS17830	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JGK51_RS17840	COG3265	gluconokinase activity
JGK51_RS17845	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JGK51_RS17850	COG3387	PFAM Glycoside hydrolase 15-related
JGK51_RS17860	COG2706	6-phosphogluconolactonase activity
JGK51_RS17905	COG2072	flavoprotein involved in K transport
JGK51_RS17925	COG3251	PFAM MbtH domain protein
JGK51_RS17935	COG1131	(ABC) transporter
JGK51_RS17945	COG0456	acetyltransferase
JGK51_RS17950	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JGK51_RS17960	COG0367	asparagine synthase
JGK51_RS17975	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JGK51_RS18025	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JGK51_RS18060	COG0673	inositol 2-dehydrogenase activity
JGK51_RS18070	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JGK51_RS18105	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JGK51_RS18115	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JGK51_RS18120	COG0318	PFAM AMP-dependent synthetase and ligase
JGK51_RS18145	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JGK51_RS18190	COG5002	protein histidine kinase activity
JGK51_RS18205	COG2318	DinB family
JGK51_RS18240	COG0667	Aldo Keto reductase
JGK51_RS18255	COG1012	belongs to the aldehyde dehydrogenase family
JGK51_RS18285	COG0583	DNA-binding transcription factor activity
JGK51_RS18290	COG1028	Short-chain dehydrogenase reductase Sdr
JGK51_RS18300	COG4257	antibiotic catabolic process
JGK51_RS18320	COG0412	Dienelactone hydrolase
JGK51_RS18340	COG5479	isomerase activity
JGK51_RS18340	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
JGK51_RS18345	COG2318	DinB family
JGK51_RS18350	COG1982	Orn Lys Arg decarboxylase major
JGK51_RS18375	COG0583	DNA-binding transcription factor activity
JGK51_RS18455	COG3903	Transcriptional regulator
JGK51_RS18455	COG3629	intracellular signal transduction
JGK51_RS18525	COG0151	Belongs to the GarS family
JGK51_RS18550	COG0515	serine threonine protein kinase
JGK51_RS18570	COG0006	proline dipeptidase activity
JGK51_RS18575	COG3291	Pkd domain containing protein
JGK51_RS18620	COG1802	Transcriptional regulator
JGK51_RS18625	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JGK51_RS18630	COG3938	Belongs to the proline racemase family
JGK51_RS18635	COG1012	belongs to the aldehyde dehydrogenase family
JGK51_RS18645	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JGK51_RS18650	COG0445	tRNA wobble uridine modification
JGK51_RS18690	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JGK51_RS18710	COG1733	regulation of RNA biosynthetic process
JGK51_RS18725	COG1773	rubredoxin
JGK51_RS18755	COG0318	PFAM AMP-dependent synthetase and ligase
JGK51_RS18770	COG2124	cytochrome p450
JGK51_RS18775	COG0477	Major facilitator Superfamily
JGK51_RS18780	COG3903	Transcriptional regulator
JGK51_RS18780	COG3629	intracellular signal transduction
JGK51_RS18800	COG2271	Major facilitator Superfamily
JGK51_RS18875	COG0583	DNA-binding transcription factor activity
JGK51_RS18895	COG0142	geranyltranstransferase activity
JGK51_RS18900	COG1119	ATPase activity
JGK51_RS18910	COG1024	Enoyl-CoA hydratase
JGK51_RS18915	COG2124	cytochrome p450
JGK51_RS18935	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
JGK51_RS18970	COG2124	cytochrome p450
JGK51_RS18975	COG1024	Enoyl-CoA hydratase
JGK51_RS18985	COG1119	ATPase activity
JGK51_RS18990	COG0142	geranyltranstransferase activity
JGK51_RS19010	COG0583	DNA-binding transcription factor activity
JGK51_RS19085	COG2271	Major facilitator Superfamily
JGK51_RS19105	COG3903	Transcriptional regulator
JGK51_RS19105	COG3629	intracellular signal transduction
JGK51_RS19110	COG0477	Major facilitator Superfamily
JGK51_RS19115	COG2124	cytochrome p450
JGK51_RS19130	COG0318	PFAM AMP-dependent synthetase and ligase
JGK51_RS19160	COG1773	rubredoxin
JGK51_RS19175	COG1733	regulation of RNA biosynthetic process
JGK51_RS19180	COG1733	regulation of RNA biosynthetic process
JGK51_RS19185	COG0702	epimerase
JGK51_RS19190	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JGK51_RS19200	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JGK51_RS19275	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
JGK51_RS19295	COG4977	sequence-specific DNA binding
JGK51_RS19305	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JGK51_RS19310	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JGK51_RS19315	COG1960	acyl-CoA dehydrogenase activity
JGK51_RS19325	COG0583	DNA-binding transcription factor activity
JGK51_RS19335	COG3979	chitinase
JGK51_RS19365	COG1349	DNA-binding transcription factor activity
JGK51_RS19395	COG1028	Short-chain dehydrogenase reductase Sdr
JGK51_RS19445	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JGK51_RS19485	COG1609	Transcriptional regulator
JGK51_RS19495	COG1175	transmembrane transport
JGK51_RS19500	COG0395	ABC-type sugar transport system, permease component
JGK51_RS19540	COG1309	transcriptional regulator
JGK51_RS19590	COG3629	intracellular signal transduction
JGK51_RS19600	COG2124	cytochrome p450
JGK51_RS19610	COG0604	alcohol dehydrogenase
JGK51_RS19630	COG3321	synthase
JGK51_RS19630	COG0604	alcohol dehydrogenase
JGK51_RS19685	COG2814	Major facilitator Superfamily
JGK51_RS19695	COG3251	PFAM MbtH domain protein
JGK51_RS19715	COG2124	cytochrome p450
JGK51_RS19725	COG0366	Alpha amylase catalytic
JGK51_RS19730	COG0395	ABC-type sugar transport system, permease component
JGK51_RS19735	COG1175	transmembrane transport
JGK51_RS19765	COG1309	transcriptional regulator
JGK51_RS19770	COG0277	FAD linked oxidase domain protein
JGK51_RS19780	COG1418	mRNA catabolic process
JGK51_RS19785	COG1733	regulation of RNA biosynthetic process
JGK51_RS19790	COG0702	epimerase
JGK51_RS19805	COG0477	Major facilitator Superfamily
JGK51_RS19815	COG2124	cytochrome p450
JGK51_RS19845	COG3631	Ketosteroid isomerase-related protein
JGK51_RS19850	COG0702	epimerase
JGK51_RS19910	COG3118	belongs to the thioredoxin family
JGK51_RS19910	COG0492	ferredoxin-NADP+ reductase activity
JGK51_RS19915	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JGK51_RS19920	COG1960	acyl-CoA dehydrogenase activity
JGK51_RS19925	COG1960	acyl-CoA dehydrogenase activity
JGK51_RS19930	COG1024	Enoyl-CoA hydratase
JGK51_RS19945	COG1309	transcriptional regulator
JGK51_RS19960	COG0076	glutamate decarboxylase activity
JGK51_RS19995	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JGK51_RS20015	COG1120	ATPase activity
JGK51_RS20020	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JGK51_RS20050	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JGK51_RS20055	COG3433	isochorismatase activity
JGK51_RS20055	COG1535	isochorismatase
JGK51_RS20060	COG0318	PFAM AMP-dependent synthetase and ligase
JGK51_RS20140	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
JGK51_RS20150	COG4260	virion core protein, lumpy skin disease virus
JGK51_RS20160	COG2814	Major facilitator Superfamily
JGK51_RS20190	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JGK51_RS20225	COG1309	transcriptional regulator
JGK51_RS20245	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JGK51_RS20265	COG1309	transcriptional regulator
JGK51_RS20300	COG3321	synthase
JGK51_RS20300	COG1028	Short-chain dehydrogenase reductase Sdr
JGK51_RS20300	COG0604	alcohol dehydrogenase
JGK51_RS20305	COG0640	Transcriptional regulator
JGK51_RS20325	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
JGK51_RS20340	COG1278	Cold shock
JGK51_RS20375	COG0069	glutamate synthase activity
JGK51_RS20395	COG4977	sequence-specific DNA binding
JGK51_RS20410	COG1609	Transcriptional regulator
JGK51_RS20420	COG1172	Belongs to the binding-protein-dependent transport system permease family
JGK51_RS20425	COG1129	ABC transporter
JGK51_RS20430	COG1879	ABC-type sugar transport system periplasmic component
JGK51_RS20440	COG1609	Transcriptional regulator
JGK51_RS20445	COG0405	Gamma-glutamyltransferase
JGK51_RS20450	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JGK51_RS20465	COG1609	Transcriptional regulator
JGK51_RS20470	COG0515	serine threonine protein kinase
JGK51_RS20470	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JGK51_RS20520	COG3896	Chloramphenicol phosphotransferase-like protein
JGK51_RS20550	COG4948	Mandelate Racemase Muconate Lactonizing
JGK51_RS20555	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JGK51_RS20560	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JGK51_RS20660	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
JGK51_RS20690	COG2814	Major facilitator Superfamily
JGK51_RS20695	COG0517	IMP dehydrogenase activity
JGK51_RS20695	COG0617	tRNA 3'-terminal CCA addition
JGK51_RS20695	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
JGK51_RS20705	COG0110	maltose O-acetyltransferase activity
JGK51_RS20730	COG0477	Major facilitator Superfamily
JGK51_RS20770	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JGK51_RS20810	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JGK51_RS20900	COG1222	aaa ATPase
JGK51_RS20945	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
JGK51_RS20945	COG0778	Nitroreductase
JGK51_RS20950	COG0604	alcohol dehydrogenase
JGK51_RS20970	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
JGK51_RS20970	COG1703	isobutyryl-CoA mutase activity
JGK51_RS20970	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
JGK51_RS20975	COG2132	Multicopper oxidase
JGK51_RS20995	COG0626	cystathionine gamma-synthase activity
JGK51_RS21000	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JGK51_RS21010	COG4106	trans-aconitate 2-methyltransferase activity
JGK51_RS21025	COG0736	holo-[acyl-carrier-protein] synthase activity
JGK51_RS21035	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JGK51_RS21040	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JGK51_RS21045	COG1410	methionine synthase
JGK51_RS21045	COG0646	methionine synthase
JGK51_RS21075	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JGK51_RS21075	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JGK51_RS21080	COG0438	transferase activity, transferring glycosyl groups
JGK51_RS21125	COG1937	Protein conserved in bacteria
JGK51_RS21195	COG1131	(ABC) transporter
JGK51_RS21210	COG0456	acetyltransferase
JGK51_RS21270	COG1396	sequence-specific DNA binding
JGK51_RS21300	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JGK51_RS21305	COG0542	response to heat
JGK51_RS21310	COG2837	iron assimilation
JGK51_RS21325	COG1597	lipid kinase activity
JGK51_RS21330	COG0277	FAD linked oxidase domain protein
JGK51_RS21360	COG1132	(ABC) transporter
JGK51_RS21380	COG3842	ATPase activity
JGK51_RS21385	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
JGK51_RS21390	COG1176	ABC-type spermidine putrescine transport system, permease component I
JGK51_RS21395	COG1177	transmembrane transport
JGK51_RS21405	COG3979	chitinase
JGK51_RS21430	COG2755	lipolytic protein G-D-S-L family
JGK51_RS21450	COG1309	transcriptional regulator
JGK51_RS21510	COG1228	amidohydrolase
JGK51_RS21515	COG0589	response to stress
JGK51_RS21520	COG0617	tRNA 3'-terminal CCA addition
JGK51_RS21520	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
JGK51_RS21520	COG0517	IMP dehydrogenase activity
JGK51_RS21550	COG0583	DNA-binding transcription factor activity
JGK51_RS21560	COG2197	response regulator
JGK51_RS21565	COG4585	Histidine kinase
JGK51_RS21595	COG1584	GPR1 FUN34 yaaH family protein
JGK51_RS21630	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JGK51_RS21635	COG2755	lipolytic protein G-D-S-L family
JGK51_RS21650	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JGK51_RS21670	COG1529	Aldehyde oxidase and xanthine dehydrogenase
JGK51_RS21675	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
JGK51_RS21680	COG2080	2 iron, 2 sulfur cluster binding
JGK51_RS21700	COG2208	phosphoserine phosphatase activity
JGK51_RS21700	COG1366	Belongs to the anti-sigma-factor antagonist family
JGK51_RS21700	COG2172	sigma factor antagonist activity
JGK51_RS21705	COG0768	penicillin binding
JGK51_RS21720	COG5002	protein histidine kinase activity
JGK51_RS21725	COG0745	RESPONSE REGULATOR receiver
JGK51_RS21765	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JGK51_RS21775	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JGK51_RS21795	COG2409	Drug exporters of the RND superfamily
JGK51_RS21800	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JGK51_RS21810	COG1090	epimerase
JGK51_RS21825	COG1316	TRANSCRIPTIONal
JGK51_RS21830	COG0640	Transcriptional regulator
JGK51_RS21900	COG1063	alcohol dehydrogenase
JGK51_RS21905	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
JGK51_RS21920	COG0517	IMP dehydrogenase activity
JGK51_RS21920	COG0516	GMP reductase activity
JGK51_RS21935	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
JGK51_RS21940	COG0589	response to stress
JGK51_RS21955	COG0701	Predicted permease
JGK51_RS21995	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
JGK51_RS22020	COG0375	protein maturation
JGK51_RS22035	COG0298	carbon dioxide binding
JGK51_RS22040	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
JGK51_RS22045	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
JGK51_RS22050	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
JGK51_RS22055	COG1024	Enoyl-CoA hydratase
JGK51_RS22055	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JGK51_RS22060	COG1285	pathogenesis
JGK51_RS22075	COG0628	permease
JGK51_RS22115	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
JGK51_RS22120	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JGK51_RS22130	COG0438	transferase activity, transferring glycosyl groups
JGK51_RS22175	COG0667	Aldo Keto reductase
JGK51_RS22185	COG0586	Pfam SNARE associated Golgi protein
JGK51_RS22190	COG0477	Major facilitator Superfamily
JGK51_RS22220	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
JGK51_RS22225	COG0437	4 iron, 4 sulfur cluster binding
JGK51_RS22250	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JGK51_RS22260	COG3383	formate dehydrogenase (NAD+) activity
JGK51_RS22260	COG0243	molybdopterin cofactor binding
JGK51_RS22265	COG0243	molybdopterin cofactor binding
JGK51_RS22265	COG3383	formate dehydrogenase (NAD+) activity
JGK51_RS22280	COG0582	viral genome integration into host DNA
JGK51_RS22580	COG0740	serine-type endopeptidase activity
JGK51_RS22725	COG1921	L-seryl-tRNASec selenium transferase activity
JGK51_RS22805	COG0673	inositol 2-dehydrogenase activity
JGK51_RS22810	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JGK51_RS22815	COG1335	isochorismatase
JGK51_RS22850	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JGK51_RS22870	COG0009	L-threonylcarbamoyladenylate synthase
JGK51_RS22895	COG0596	Alpha beta hydrolase
JGK51_RS22915	COG0656	L-ascorbic acid biosynthetic process
JGK51_RS22930	COG2208	phosphoserine phosphatase activity
JGK51_RS22955	COG1793	dna ligase
JGK51_RS22960	COG0181	hydroxymethylbilane synthase activity
JGK51_RS22970	COG0842	Transport permease protein
JGK51_RS23015	COG0366	Alpha amylase catalytic
JGK51_RS23025	COG3281	Trehalose synthase
JGK51_RS23030	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
JGK51_RS23035	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
JGK51_RS23050	COG1252	NADH dehydrogenase
JGK51_RS23105	COG5002	protein histidine kinase activity
JGK51_RS23145	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JGK51_RS23190	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JGK51_RS23215	COG0667	Aldo Keto reductase
JGK51_RS23220	COG0328	RNA-DNA hybrid ribonuclease activity
JGK51_RS23245	COG1191	sigma factor activity
JGK51_RS23270	COG0667	Aldo Keto reductase
JGK51_RS23275	COG0583	DNA-binding transcription factor activity
JGK51_RS23285	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
JGK51_RS23315	COG0531	amino acid
JGK51_RS23320	COG3250	beta-galactosidase activity
JGK51_RS23365	COG0367	asparagine synthase
JGK51_RS23375	COG0673	inositol 2-dehydrogenase activity
JGK51_RS23380	COG3511	phospholipase C
JGK51_RS23400	COG0510	thiamine kinase activity
JGK51_RS23440	COG1024	Enoyl-CoA hydratase
JGK51_RS23465	COG0318	PFAM AMP-dependent synthetase and ligase
JGK51_RS23475	COG2070	2-Nitropropane dioxygenase
JGK51_RS23490	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JGK51_RS23495	COG0662	Cupin 2, conserved barrel domain protein
JGK51_RS23500	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JGK51_RS23505	COG1131	(ABC) transporter
JGK51_RS23530	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JGK51_RS23545	COG0494	nUDIX hydrolase
JGK51_RS23550	COG0561	phosphatase activity
JGK51_RS23555	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JGK51_RS23565	COG4989	oxidoreductase activity
JGK51_RS23570	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JGK51_RS23575	COG1028	Short-chain dehydrogenase reductase Sdr
JGK51_RS23590	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JGK51_RS23620	COG2124	cytochrome p450
JGK51_RS23635	COG3483	tryptophan 2,3-dioxygenase activity
JGK51_RS23655	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JGK51_RS23670	COG3251	PFAM MbtH domain protein
JGK51_RS23730	COG0071	Belongs to the small heat shock protein (HSP20) family
JGK51_RS23735	COG3634	alkyl hydroperoxide reductase activity
JGK51_RS23750	COG0542	response to heat
JGK51_RS23765	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JGK51_RS23770	COG0443	Heat shock 70 kDa protein
JGK51_RS23780	COG3835	regulator
JGK51_RS23790	COG2814	Major facilitator Superfamily
JGK51_RS23815	COG2239	Acts as a magnesium transporter
JGK51_RS23820	COG0531	amino acid
JGK51_RS23825	COG1960	acyl-CoA dehydrogenase activity
JGK51_RS23850	COG1674	ftsk spoiiie
JGK51_RS23870	COG0464	growth
JGK51_RS23910	COG2376	Dihydroxyacetone kinase
JGK51_RS23915	COG1461	Dihydroxyacetone kinase
JGK51_RS23920	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
JGK51_RS23930	COG4733	cellulase activity
JGK51_RS23930	COG5297	Belongs to the glycosyl hydrolase family 6
JGK51_RS23945	COG0446	pyridine nucleotide-disulphide oxidoreductase
JGK51_RS23945	COG1902	pentaerythritol trinitrate reductase activity
JGK51_RS23970	COG2890	protein-(glutamine-N5) methyltransferase activity
JGK51_RS23985	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JGK51_RS24000	COG3458	cephalosporin-C deacetylase activity
JGK51_RS24005	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JGK51_RS24020	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
JGK51_RS24025	COG5650	phosphatidylinositol metabolic process
JGK51_RS24035	COG2066	Belongs to the glutaminase family
JGK51_RS24055	COG1968	undecaprenyl-diphosphatase activity
JGK51_RS24060	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JGK51_RS24065	COG1993	acr, cog1993
JGK51_RS24070	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JGK51_RS24105	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JGK51_RS24135	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JGK51_RS24140	COG2409	Drug exporters of the RND superfamily
JGK51_RS24145	COG1309	transcriptional regulator
JGK51_RS24155	COG3469	chitinase activity
JGK51_RS24190	COG4106	trans-aconitate 2-methyltransferase activity
JGK51_RS24215	COG4191	Histidine kinase
JGK51_RS24220	COG0549	Belongs to the carbamate kinase family
JGK51_RS24225	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JGK51_RS24235	COG0531	amino acid
JGK51_RS24240	COG4716	Myosin-crossreactive antigen
JGK51_RS24250	COG1028	Short-chain dehydrogenase reductase Sdr
JGK51_RS24275	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
JGK51_RS24280	COG1215	transferase activity, transferring glycosyl groups
JGK51_RS24320	COG1349	DNA-binding transcription factor activity
JGK51_RS24355	COG0492	ferredoxin-NADP+ reductase activity
JGK51_RS24370	COG2192	nodulation
JGK51_RS24420	COG1940	carbohydrate kinase activity
JGK51_RS24440	COG2813	Specifically methylates the guanine in position
JGK51_RS24455	COG1349	DNA-binding transcription factor activity
JGK51_RS24465	COG1595	DNA-templated transcription, initiation
JGK51_RS24490	COG0180	Tryptophanyl-tRNA synthetase
JGK51_RS24515	COG0445	tRNA wobble uridine modification
JGK51_RS24525	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JGK51_RS24530	COG1660	Displays ATPase and GTPase activities
JGK51_RS24550	COG3345	alpha-galactosidase
JGK51_RS24575	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
JGK51_RS24630	COG0584	glycerophosphoryl diester phosphodiesterase
JGK51_RS24665	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JGK51_RS24680	COG0546	phosphoglycolate phosphatase activity
JGK51_RS24685	COG1309	transcriptional regulator
JGK51_RS24700	COG0640	Transcriptional regulator
JGK51_RS24705	COG1902	pentaerythritol trinitrate reductase activity
JGK51_RS24725	COG1960	acyl-CoA dehydrogenase activity
JGK51_RS24745	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
JGK51_RS24760	COG2706	6-phosphogluconolactonase activity
JGK51_RS24775	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JGK51_RS24780	COG0477	Major facilitator Superfamily
JGK51_RS24805	COG0714	Associated with various cellular activities
JGK51_RS24820	COG1472	Belongs to the glycosyl hydrolase 3 family
JGK51_RS24835	COG0432	Pfam Uncharacterised protein family UPF0047
JGK51_RS24840	COG2072	flavoprotein involved in K transport
JGK51_RS24850	COG1132	(ABC) transporter
JGK51_RS24885	COG1132	(ABC) transporter
JGK51_RS24895	COG0254	rRNA binding
JGK51_RS24910	COG1946	Acyl-CoA thioesterase
JGK51_RS24920	COG2018	Roadblock/LC7 domain
JGK51_RS24970	COG1940	carbohydrate kinase activity
JGK51_RS24995	COG1012	belongs to the aldehyde dehydrogenase family
JGK51_RS25000	COG1408	metallophosphoesterase
JGK51_RS25005	COG0583	DNA-binding transcription factor activity
JGK51_RS25025	COG0714	Associated with various cellular activities
JGK51_RS25065	COG0446	pyridine nucleotide-disulphide oxidoreductase
JGK51_RS25065	COG1902	pentaerythritol trinitrate reductase activity
JGK51_RS25120	COG0512	Glutamine amidotransferase of anthranilate synthase
JGK51_RS25120	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JGK51_RS25130	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JGK51_RS25140	COG0662	Cupin 2, conserved barrel domain protein
JGK51_RS25145	COG1960	acyl-CoA dehydrogenase activity
JGK51_RS25155	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
JGK51_RS25175	COG4865	methylaspartate mutase activity
JGK51_RS25185	COG2197	response regulator
JGK51_RS25190	COG2986	histidine ammonia-lyase
JGK51_RS25200	COG0367	asparagine synthase
JGK51_RS25225	COG0477	Major facilitator Superfamily
JGK51_RS25230	COG2264	protein methyltransferase activity
JGK51_RS25265	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JGK51_RS25270	COG3251	PFAM MbtH domain protein
JGK51_RS25275	COG0318	PFAM AMP-dependent synthetase and ligase
JGK51_RS25285	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JGK51_RS25295	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JGK51_RS25300	COG0443	Heat shock 70 kDa protein
JGK51_RS25310	COG3959	Transketolase, thiamine diphosphate binding domain
JGK51_RS25335	COG3629	intracellular signal transduction
JGK51_RS25335	COG3903	Transcriptional regulator
JGK51_RS25370	COG2423	ornithine cyclodeaminase activity
JGK51_RS25375	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JGK51_RS25385	COG2197	response regulator
JGK51_RS25400	COG0464	growth
JGK51_RS25480	COG0586	Pfam SNARE associated Golgi protein
JGK51_RS25515	COG1960	acyl-CoA dehydrogenase activity
JGK51_RS25520	COG1960	acyl-CoA dehydrogenase activity
JGK51_RS25535	COG1793	dna ligase
JGK51_RS25555	COG3424	synthase
JGK51_RS25560	COG2124	cytochrome p450
JGK51_RS25570	COG1960	acyl-CoA dehydrogenase activity
JGK51_RS25580	COG0242	peptide deformylase activity
JGK51_RS25590	COG3442	glutamine amidotransferase
JGK51_RS25595	COG0205	6-phosphofructokinase activity
JGK51_RS25610	COG1522	sequence-specific DNA binding
JGK51_RS25615	COG1834	amidinotransferase
JGK51_RS25620	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JGK51_RS25630	COG0204	Acyl-transferase
JGK51_RS25635	COG0829	nickel cation binding
JGK51_RS25640	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
JGK51_RS25650	COG0804	urea catabolic process
JGK51_RS25655	COG0832	Belongs to the urease beta subunit family
JGK51_RS25660	COG0831	urea catabolic process
JGK51_RS25670	COG0740	serine-type endopeptidase activity
JGK51_RS25705	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
JGK51_RS25710	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JGK51_RS25715	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
JGK51_RS25720	COG2226	methyltransferase
JGK51_RS25735	COG1136	(ABC) transporter
JGK51_RS25735	COG0577	efflux transmembrane transporter activity
JGK51_RS25740	COG0577	efflux transmembrane transporter activity
JGK51_RS25740	COG1136	(ABC) transporter
JGK51_RS25750	COG0456	acetyltransferase
JGK51_RS25770	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JGK51_RS25790	COG4585	Histidine kinase
JGK51_RS25795	COG2197	response regulator
JGK51_RS25800	COG1940	carbohydrate kinase activity
JGK51_RS25810	COG2188	Transcriptional regulator
JGK51_RS25815	COG1595	DNA-templated transcription, initiation
JGK51_RS25825	COG2267	carboxylic ester hydrolase activity
JGK51_RS25845	COG0626	cystathionine gamma-synthase activity
JGK51_RS25880	COG0419	ATPase involved in DNA repair
JGK51_RS25885	COG0420	3'-5' exonuclease activity
JGK51_RS25890	COG1739	Uncharacterized protein family UPF0029
JGK51_RS25905	COG1832	CoA-binding protein
JGK51_RS25910	COG0531	amino acid
JGK51_RS25915	COG0640	Transcriptional regulator
JGK51_RS25940	COG0110	maltose O-acetyltransferase activity
JGK51_RS25965	COG1819	glycosyl
JGK51_RS25970	COG0596	Alpha beta hydrolase
JGK51_RS25985	COG0604	alcohol dehydrogenase
JGK51_RS25985	COG3321	synthase
JGK51_RS26010	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JGK51_RS26025	COG0183	Belongs to the thiolase family
JGK51_RS26050	COG0815	Transfers the fatty acyl group on membrane lipoproteins
JGK51_RS26055	COG0673	inositol 2-dehydrogenase activity
JGK51_RS26070	COG2318	DinB family
JGK51_RS26085	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
JGK51_RS26090	COG0747	negative chemotaxis
JGK51_RS26130	COG0697	spore germination
JGK51_RS26145	COG0697	spore germination
JGK51_RS26185	COG0509	glycine decarboxylation via glycine cleavage system
JGK51_RS26260	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JGK51_RS26260	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JGK51_RS26270	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JGK51_RS26290	COG1716	ATPase activity
JGK51_RS26310	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
JGK51_RS26340	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JGK51_RS26350	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JGK51_RS26400	COG2018	Roadblock/LC7 domain
JGK51_RS26415	COG1414	Transcriptional regulator
JGK51_RS26440	COG2814	Major facilitator Superfamily
JGK51_RS26445	COG4336	lyase activity
JGK51_RS26450	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
JGK51_RS26455	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
JGK51_RS26460	COG1984	allophanate hydrolase subunit 2
JGK51_RS26465	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JGK51_RS26485	COG0438	transferase activity, transferring glycosyl groups
JGK51_RS26515	COG2364	Membrane
JGK51_RS26525	COG2270	Major facilitator Superfamily
JGK51_RS26540	COG1216	Glycosyl transferase, family 2
JGK51_RS26565	COG1960	acyl-CoA dehydrogenase activity
JGK51_RS26620	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
JGK51_RS26625	COG0140	phosphoribosyl-ATP diphosphatase activity
JGK51_RS26630	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
JGK51_RS26635	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JGK51_RS26635	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JGK51_RS26640	COG3201	nicotinamide mononucleotide transporter
JGK51_RS26655	COG1846	Transcriptional regulator
JGK51_RS26655	COG1940	carbohydrate kinase activity
JGK51_RS26660	COG0738	Major facilitator superfamily
JGK51_RS26670	COG2233	PERMEase
JGK51_RS26690	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JGK51_RS26715	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JGK51_RS26720	COG3842	ATPase activity
JGK51_RS26730	COG1176	ABC-type spermidine putrescine transport system, permease component I
JGK51_RS26740	COG2188	Transcriptional regulator
JGK51_RS26750	COG0531	amino acid
JGK51_RS26770	COG3903	Transcriptional regulator
JGK51_RS26770	COG3629	intracellular signal transduction
JGK51_RS26785	COG2390	Transcriptional regulator
JGK51_RS26790	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JGK51_RS26800	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JGK51_RS26820	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JGK51_RS26835	COG0194	GDP metabolic process
JGK51_RS26845	COG0284	orotidine-5'-phosphate decarboxylase activity
JGK51_RS26850	COG0167	dihydroorotate dehydrogenase activity
JGK51_RS26855	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JGK51_RS26860	COG0505	Belongs to the CarA family
JGK51_RS26870	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JGK51_RS26875	COG0540	Belongs to the ATCase OTCase family
JGK51_RS26880	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JGK51_RS26890	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JGK51_RS26895	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JGK51_RS26900	COG0006	proline dipeptidase activity
JGK51_RS26910	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JGK51_RS26915	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JGK51_RS26920	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
JGK51_RS26925	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JGK51_RS26930	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JGK51_RS26935	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JGK51_RS26940	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JGK51_RS26960	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JGK51_RS26975	COG0124	histidyl-tRNA synthetase
JGK51_RS26985	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JGK51_RS26990	COG1196	nuclear chromosome segregation
JGK51_RS26995	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JGK51_RS27000	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JGK51_RS27005	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JGK51_RS27010	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JGK51_RS27020	COG2255	four-way junction helicase activity
JGK51_RS27025	COG0632	four-way junction helicase activity
JGK51_RS27030	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
JGK51_RS27035	COG0217	transcriptional regulatory protein
JGK51_RS27040	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
JGK51_RS27045	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
JGK51_RS27055	COG0438	transferase activity, transferring glycosyl groups
JGK51_RS27060	COG1560	Kdo2-lipid A biosynthetic process
JGK51_RS27065	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JGK51_RS27085	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JGK51_RS27100	COG5002	protein histidine kinase activity
JGK51_RS27100	COG2176	DNA-directed DNA polymerase activity
JGK51_RS27165	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JGK51_RS27215	COG1648	precorrin-2 dehydrogenase activity
JGK51_RS27215	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JGK51_RS27220	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
JGK51_RS27235	COG1464	Belongs to the NlpA lipoprotein family
JGK51_RS27240	COG2011	ABC-type metal ion transport system permease component
JGK51_RS27245	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JGK51_RS27250	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JGK51_RS27280	COG2132	Multicopper oxidase
JGK51_RS27285	COG0477	Major facilitator Superfamily
JGK51_RS27300	COG0165	Argininosuccinate lyase
JGK51_RS27305	COG0137	argininosuccinate synthase activity
JGK51_RS27320	COG2205	protein histidine kinase activity
JGK51_RS27325	COG0745	RESPONSE REGULATOR receiver
JGK51_RS27350	COG1132	(ABC) transporter
JGK51_RS27365	COG1438	arginine binding
JGK51_RS27370	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JGK51_RS27375	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
JGK51_RS27380	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
JGK51_RS27385	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JGK51_RS27405	COG1574	metal-dependent hydrolase with the TIM-barrel fold
JGK51_RS27410	COG2197	response regulator
JGK51_RS27420	COG0463	Glycosyl transferase, family 2
JGK51_RS27470	COG1649	PFAM Uncharacterised BCR, COG1649
JGK51_RS27500	COG0072	phenylalanine-tRNA ligase activity
JGK51_RS27500	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JGK51_RS27505	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JGK51_RS27510	COG5002	protein histidine kinase activity
JGK51_RS27515	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JGK51_RS27520	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
JGK51_RS27525	COG0291	Belongs to the bacterial ribosomal protein bL35 family
JGK51_RS27530	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
JGK51_RS27565	COG1012	belongs to the aldehyde dehydrogenase family
JGK51_RS27570	COG0174	glutamine synthetase
JGK51_RS27575	COG2186	Transcriptional regulator
JGK51_RS27580	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
JGK51_RS27595	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JGK51_RS27605	COG4176	ABC-type proline glycine betaine transport system permease component
JGK51_RS27610	COG4175	Glycine betaine
JGK51_RS27610	COG0517	IMP dehydrogenase activity
JGK51_RS27615	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JGK51_RS27635	COG0564	pseudouridine synthase activity
JGK51_RS27670	COG0805	protein transport
JGK51_RS27675	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JGK51_RS27705	COG0545	Peptidyl-prolyl cis-trans isomerase
JGK51_RS27710	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
JGK51_RS27720	COG1609	Transcriptional regulator
JGK51_RS27725	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
JGK51_RS27730	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
JGK51_RS27745	COG4122	O-methyltransferase activity
JGK51_RS27750	COG1222	aaa ATPase
JGK51_RS27770	COG1994	Peptidase M50
JGK51_RS27770	COG0517	IMP dehydrogenase activity
JGK51_RS27780	COG2197	response regulator
JGK51_RS27785	COG0747	negative chemotaxis
JGK51_RS27795	COG1410	methionine synthase
JGK51_RS27795	COG0646	methionine synthase
JGK51_RS27800	COG1414	Transcriptional regulator
JGK51_RS27805	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JGK51_RS27810	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JGK51_RS27815	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
JGK51_RS27825	COG0215	cysteine-tRNA ligase activity
JGK51_RS27840	COG0406	alpha-ribazole phosphatase activity
JGK51_RS27845	COG0598	Magnesium transport protein CorA
JGK51_RS27850	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JGK51_RS27855	COG0667	Aldo Keto reductase
JGK51_RS27895	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JGK51_RS27895	COG1796	DNA polymerase
JGK51_RS27915	COG3012	SEC-C Motif Domain Protein
JGK51_RS27920	COG2186	Transcriptional regulator
JGK51_RS27925	COG3265	gluconokinase activity
JGK51_RS27955	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
JGK51_RS27975	COG0318	PFAM AMP-dependent synthetase and ligase
JGK51_RS27980	COG1028	Short-chain dehydrogenase reductase Sdr
JGK51_RS27985	COG3876	Protein conserved in bacteria
JGK51_RS28035	COG1960	acyl-CoA dehydrogenase activity
JGK51_RS28070	COG0243	molybdopterin cofactor binding
JGK51_RS28075	COG1309	transcriptional regulator
JGK51_RS28085	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
JGK51_RS28090	COG2188	Transcriptional regulator
JGK51_RS28115	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JGK51_RS28125	COG2755	lipolytic protein G-D-S-L family
JGK51_RS28145	COG0726	polysaccharide deacetylase
JGK51_RS28170	COG1725	Transcriptional regulator
JGK51_RS28195	COG0662	Cupin 2, conserved barrel domain protein
JGK51_RS28195	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JGK51_RS28205	COG0587	DNA-directed DNA polymerase activity
JGK51_RS28230	COG1126	abc transporter atp-binding protein
JGK51_RS28240	COG0765	amino acid transport
JGK51_RS28245	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JGK51_RS28255	COG1799	cell septum assembly
JGK51_RS28260	COG1960	acyl-CoA dehydrogenase activity
JGK51_RS28265	COG0477	Major facilitator Superfamily
JGK51_RS28275	COG0671	phosphoesterase, PA-phosphatase related
JGK51_RS28285	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JGK51_RS28290	COG1652	LysM domain
JGK51_RS28305	COG1160	GTP binding
JGK51_RS28315	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
JGK51_RS28340	COG3541	Predicted nucleotidyltransferase
JGK51_RS28350	COG1187	pseudouridine synthase activity
JGK51_RS28355	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JGK51_RS28360	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
JGK51_RS28375	COG0686	Belongs to the AlaDH PNT family
JGK51_RS28385	COG0494	nUDIX hydrolase
JGK51_RS28390	COG0504	CTP synthase activity
JGK51_RS28395	COG3387	PFAM Glycoside hydrolase 15-related
JGK51_RS28410	COG0297	glycogen (starch) synthase activity
JGK51_RS28420	COG0497	DNA recombination
JGK51_RS28425	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JGK51_RS28445	COG1120	ATPase activity
JGK51_RS28450	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JGK51_RS28455	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JGK51_RS28460	COG0647	UMP catabolic process
JGK51_RS28495	COG2094	Belongs to the DNA glycosylase MPG family
JGK51_RS28505	COG1881	PFAM PEBP family protein
JGK51_RS28525	COG1119	ATPase activity
JGK51_RS28540	COG2197	response regulator
JGK51_RS28545	COG4585	Histidine kinase
JGK51_RS28550	COG1028	Short-chain dehydrogenase reductase Sdr
JGK51_RS28555	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
JGK51_RS28565	COG1131	(ABC) transporter
JGK51_RS28565	COG0842	Transport permease protein
JGK51_RS28565	COG1716	ATPase activity
JGK51_RS28570	COG0560	Phosphoserine phosphatase
JGK51_RS28570	COG3830	Belongs to the UPF0237 family
JGK51_RS28575	COG0588	phosphoglycerate mutase activity
JGK51_RS28590	COG2186	Transcriptional regulator
JGK51_RS28620	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JGK51_RS28640	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JGK51_RS28645	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JGK51_RS28655	COG1404	Belongs to the peptidase S8 family
JGK51_RS28660	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JGK51_RS28670	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JGK51_RS28685	COG3387	PFAM Glycoside hydrolase 15-related
JGK51_RS28715	COG1302	Protein conserved in bacteria
JGK51_RS28725	COG1024	Enoyl-CoA hydratase
JGK51_RS28735	COG0488	(ABC) transporter
JGK51_RS28755	COG0235	Class ii aldolase
JGK51_RS28775	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
JGK51_RS28780	COG1492	cobalamin metabolic process
JGK51_RS28800	COG1797	cobyrinic acid a,c-diamide synthase activity
JGK51_RS28835	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
JGK51_RS28860	COG0765	amino acid transport
JGK51_RS28870	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JGK51_RS28875	COG2318	DinB family
JGK51_RS28880	COG0456	acetyltransferase
JGK51_RS28885	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JGK51_RS28890	COG1917	Cupin 2, conserved barrel domain protein
JGK51_RS28895	COG5285	phytanoyl-CoA dioxygenase
JGK51_RS28900	COG0156	8-amino-7-oxononanoate synthase activity
JGK51_RS28915	COG1414	Transcriptional regulator
JGK51_RS28950	COG1349	DNA-binding transcription factor activity
JGK51_RS28960	COG1175	transmembrane transport
JGK51_RS28965	COG0395	ABC-type sugar transport system, permease component
JGK51_RS29025	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JGK51_RS29035	COG2171	N-acyltransferase activity
JGK51_RS29040	COG3226	Transcriptional regulator
JGK51_RS29055	COG0822	iron-sulfur transferase activity
JGK51_RS29060	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JGK51_RS29065	COG0396	ATPase activity
JGK51_RS29075	COG0719	Fe-S assembly protein
JGK51_RS29090	COG2746	aminoglycoside 3-N-acetyltransferase activity
JGK51_RS29095	COG1131	(ABC) transporter
JGK51_RS29120	COG0109	protoheme IX farnesyltransferase activity
JGK51_RS29130	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JGK51_RS29145	COG0363	glucosamine-6-phosphate deaminase activity
JGK51_RS29155	COG0166	Belongs to the GPI family
JGK51_RS29170	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JGK51_RS29180	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JGK51_RS29185	COG1481	regulation of sporulation
JGK51_RS29195	COG1660	Displays ATPase and GTPase activities
JGK51_RS29200	COG0322	excinuclease ABC activity
JGK51_RS29215	COG1609	Transcriptional regulator
JGK51_RS29225	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JGK51_RS29240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JGK51_RS29245	COG0765	amino acid transport
JGK51_RS29255	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
JGK51_RS29260	COG0477	Major facilitator Superfamily
JGK51_RS29265	COG0387	Pfam Sodium calcium exchanger
JGK51_RS29285	COG0556	nucleotide-excision repair
JGK51_RS29295	COG0584	glycerophosphoryl diester phosphodiesterase
JGK51_RS29300	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JGK51_RS29305	COG2313	pseudouridylate synthase activity
JGK51_RS29315	COG2226	methyltransferase
JGK51_RS29320	COG0598	Magnesium transport protein CorA
JGK51_RS29400	COG2226	methyltransferase
JGK51_RS29415	COG0237	dephospho-CoA kinase activity
JGK51_RS29430	COG0539	negative regulation of cytoplasmic translation
JGK51_RS29435	COG2226	methyltransferase
JGK51_RS29440	COG1643	Atp-dependent helicase
JGK51_RS29475	COG2050	protein possibly involved in aromatic compounds catabolism
JGK51_RS29480	COG0683	leucine binding
JGK51_RS29545	COG0287	Prephenate dehydrogenase
JGK51_RS29545	COG1605	Chorismate mutase
JGK51_RS29565	COG1028	Short-chain dehydrogenase reductase Sdr
JGK51_RS29575	COG1024	Enoyl-CoA hydratase
JGK51_RS29600	COG1309	transcriptional regulator
JGK51_RS29605	COG1028	Short-chain dehydrogenase reductase Sdr
JGK51_RS29610	COG1960	acyl-CoA dehydrogenase activity
JGK51_RS29615	COG1960	acyl-CoA dehydrogenase activity
JGK51_RS29635	COG0067	glutamate synthase
JGK51_RS29635	COG0069	glutamate synthase activity
JGK51_RS29635	COG0070	glutamate synthase
JGK51_RS29645	COG1397	ADP-ribosylglycohydrolase
JGK51_RS29665	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JGK51_RS29670	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JGK51_RS29680	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JGK51_RS29690	COG0159	tryptophan synthase activity
JGK51_RS29695	COG0133	tryptophan synthase activity
JGK51_RS29705	COG0134	indole-3-glycerol-phosphate synthase activity
JGK51_RS29730	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
JGK51_RS29740	COG0346	lactoylglutathione lyase activity
JGK51_RS29755	COG0107	imidazoleglycerol-phosphate synthase activity
JGK51_RS29760	COG0251	oxidation-reduction process
JGK51_RS29765	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
JGK51_RS29770	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JGK51_RS29780	COG0131	Imidazoleglycerol-phosphate dehydratase
JGK51_RS29785	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JGK51_RS29790	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JGK51_RS29810	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JGK51_RS29830	COG1432	Conserved Protein
JGK51_RS29840	COG0587	DNA-directed DNA polymerase activity
JGK51_RS29865	COG2801	Transposase and inactivated derivatives
JGK51_RS29865	COG3415	Transposase
JGK51_RS29890	COG2153	protein acetylation
JGK51_RS29900	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JGK51_RS29910	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JGK51_RS29925	COG1799	cell septum assembly
JGK51_RS29935	COG1496	oxidoreductase activity
JGK51_RS29940	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JGK51_RS29945	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
JGK51_RS29950	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JGK51_RS29960	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JGK51_RS29965	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JGK51_RS29975	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JGK51_RS29990	COG0275	rRNA processing
JGK51_RS30000	COG0714	Associated with various cellular activities
JGK51_RS30030	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
JGK51_RS30035	COG1511	domain protein
JGK51_RS30040	COG1309	transcriptional regulator
JGK51_RS30065	COG0352	thiamine-phosphate diphosphorylase activity
JGK51_RS30085	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JGK51_RS30085	COG2022	thiamine diphosphate biosynthetic process
JGK51_RS30095	COG2022	thiamine diphosphate biosynthetic process
JGK51_RS30100	COG0515	serine threonine protein kinase
JGK51_RS30100	COG2815	serine threonine protein kinase
JGK51_RS30105	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
JGK51_RS30110	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JGK51_RS30115	COG2193	ferroxidase activity
JGK51_RS30125	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
JGK51_RS30140	COG0205	6-phosphofructokinase activity
JGK51_RS30150	COG4585	Histidine kinase
JGK51_RS30175	COG1940	carbohydrate kinase activity
JGK51_RS30185	COG0003	Pfam Anion-transporting ATPase
JGK51_RS30205	COG0438	transferase activity, transferring glycosyl groups
JGK51_RS30220	COG3883	PFAM NLP P60 protein
JGK51_RS30220	COG0791	NLP P60 protein
JGK51_RS30250	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JGK51_RS30255	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JGK51_RS30260	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
JGK51_RS30265	COG0723	plastoquinol--plastocyanin reductase activity
JGK51_RS30270	COG2010	Cytochrome c
JGK51_RS30275	COG1845	cytochrome c oxidase, subunit III
JGK51_RS30285	COG1376	ErfK ybiS ycfS ynhG family protein
JGK51_RS30295	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JGK51_RS30300	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JGK51_RS30310	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JGK51_RS30335	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
JGK51_RS30370	COG1518	maintenance of DNA repeat elements
JGK51_RS30375	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JGK51_RS30380	COG4585	Histidine kinase
JGK51_RS30385	COG2197	response regulator
JGK51_RS30390	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JGK51_RS30420	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JGK51_RS30440	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
JGK51_RS30460	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
JGK51_RS30465	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JGK51_RS30470	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JGK51_RS30475	COG0508	dehydrogenase complex catalyzes the overall conversion of
JGK51_RS30495	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
JGK51_RS30535	COG0321	lipoyl(octanoyl) transferase activity
JGK51_RS30540	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
JGK51_RS30560	COG0174	glutamine synthetase
JGK51_RS30590	COG0501	Belongs to the peptidase M48B family
JGK51_RS30625	COG0745	RESPONSE REGULATOR receiver
JGK51_RS30640	COG2197	response regulator
JGK51_RS30680	COG0366	Alpha amylase catalytic
JGK51_RS30685	COG3833	ABC-type maltose transport systems, permease component
JGK51_RS30690	COG1175	transmembrane transport
JGK51_RS30695	COG1653	transport
JGK51_RS30700	COG1609	Transcriptional regulator
JGK51_RS30710	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
JGK51_RS30725	COG0174	glutamine synthetase
JGK51_RS30730	COG1017	nitric oxide dioxygenase activity
JGK51_RS30730	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JGK51_RS30735	COG1959	2 iron, 2 sulfur cluster binding
JGK51_RS30760	COG0596	Alpha beta hydrolase
JGK51_RS30770	COG0583	DNA-binding transcription factor activity
JGK51_RS30830	COG2814	Major facilitator Superfamily
JGK51_RS30845	COG0477	Major facilitator Superfamily
JGK51_RS30850	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
JGK51_RS30855	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JGK51_RS30880	COG1994	Peptidase M50
JGK51_RS30940	COG4558	Periplasmic binding protein
JGK51_RS30945	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JGK51_RS30950	COG1120	ATPase activity
JGK51_RS30960	COG2837	iron assimilation
JGK51_RS30965	COG0672	)-iron permease
JGK51_RS30985	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JGK51_RS30990	COG2814	Major facilitator Superfamily
JGK51_RS31000	COG1686	Belongs to the peptidase S11 family
JGK51_RS31080	COG0174	glutamine synthetase
JGK51_RS31090	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JGK51_RS31095	COG0151	Belongs to the GarS family
JGK51_RS31125	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JGK51_RS31135	COG3022	response to hydroperoxide
JGK51_RS31140	COG0800	Aldolase
JGK51_RS31155	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JGK51_RS31165	COG1028	Short-chain dehydrogenase reductase Sdr
JGK51_RS31175	COG2030	dehydratase
JGK51_RS31180	COG1131	(ABC) transporter
JGK51_RS31190	COG4585	Histidine kinase
JGK51_RS31195	COG2197	response regulator
JGK51_RS31205	COG0183	Belongs to the thiolase family
JGK51_RS31210	COG0477	Major facilitator Superfamily
JGK51_RS31225	COG0860	N-Acetylmuramoyl-L-alanine amidase
JGK51_RS31235	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JGK51_RS31255	COG0438	transferase activity, transferring glycosyl groups
JGK51_RS31260	COG1309	transcriptional regulator
JGK51_RS31325	COG3845	ABC transporter
JGK51_RS31335	COG0741	lytic transglycosylase activity
JGK51_RS31340	COG3619	membrane
JGK51_RS31345	COG2124	cytochrome p450
JGK51_RS31350	COG0183	Belongs to the thiolase family
JGK51_RS31360	COG0477	Major facilitator Superfamily
JGK51_RS31370	COG4122	O-methyltransferase activity
JGK51_RS31385	COG0583	DNA-binding transcription factor activity
JGK51_RS31420	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JGK51_RS31450	COG3973	AAA domain
JGK51_RS31495	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JGK51_RS31510	COG1358	cellular component organization or biogenesis
JGK51_RS31555	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
JGK51_RS31560	COG0477	Major facilitator Superfamily
JGK51_RS31565	COG1309	transcriptional regulator
JGK51_RS31580	COG0667	Aldo Keto reductase
JGK51_RS31585	COG0789	Transcriptional regulator
JGK51_RS31620	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JGK51_RS31625	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JGK51_RS31630	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JGK51_RS31660	COG1335	isochorismatase
JGK51_RS31665	COG1335	isochorismatase
JGK51_RS31690	COG2130	NADP-dependent
JGK51_RS31735	COG0477	Major facilitator Superfamily
JGK51_RS31780	COG0318	PFAM AMP-dependent synthetase and ligase
JGK51_RS31785	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JGK51_RS31785	COG0825	malonyl-CoA metabolic process
JGK51_RS31790	COG1404	Belongs to the peptidase S8 family
JGK51_RS31815	COG1077	Cell shape determining protein MreB Mrl
JGK51_RS31860	COG0515	serine threonine protein kinase
JGK51_RS31905	COG1070	Carbohydrate kinase
JGK51_RS31920	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JGK51_RS31925	COG0358	DNA primase activity
JGK51_RS31935	COG0232	Belongs to the dGTPase family. Type 2 subfamily
JGK51_RS31940	COG2949	membrane
JGK51_RS31965	COG0395	ABC-type sugar transport system, permease component
JGK51_RS31970	COG1175	transmembrane transport
JGK51_RS31985	COG2318	DinB family
JGK51_RS31990	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JGK51_RS31990	COG0574	Belongs to the PEP-utilizing enzyme family
JGK51_RS31995	COG1940	carbohydrate kinase activity
JGK51_RS31995	COG1846	Transcriptional regulator
JGK51_RS32000	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
JGK51_RS32035	COG0477	Major facilitator Superfamily
JGK51_RS32050	COG0667	Aldo Keto reductase
JGK51_RS32060	COG0423	glycine-tRNA ligase activity
JGK51_RS32070	COG1121	(ABC) transporter
JGK51_RS32075	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JGK51_RS32085	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JGK51_RS32090	COG1381	Involved in DNA repair and RecF pathway recombination
JGK51_RS32100	COG0515	serine threonine protein kinase
JGK51_RS32135	COG1396	sequence-specific DNA binding
JGK51_RS32140	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
JGK51_RS32145	COG0747	negative chemotaxis
JGK51_RS32155	COG0444	Belongs to the ABC transporter superfamily
JGK51_RS32160	COG4608	Belongs to the ABC transporter superfamily
JGK51_RS32165	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JGK51_RS32170	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JGK51_RS32190	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JGK51_RS32220	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JGK51_RS32255	COG1619	proteins homologs of microcin C7 resistance protein MccF
JGK51_RS32260	COG2315	Protein conserved in bacteria
JGK51_RS32270	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JGK51_RS32285	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
JGK51_RS32290	COG1234	tRNA 3'-trailer cleavage
JGK51_RS32295	COG0537	adenosine 5'-monophosphoramidase activity
JGK51_RS32305	COG0793	Belongs to the peptidase S41A family
JGK51_RS32305	COG4946	Tricorn protease homolog
JGK51_RS32330	COG0484	heat shock protein binding
JGK51_RS32335	COG1420	regulation of RNA biosynthetic process
JGK51_RS32365	COG0481	GTPase activity
JGK51_RS32370	COG0268	Binds directly to 16S ribosomal RNA
JGK51_RS32385	COG2353	YceI-like domain
JGK51_RS32400	COG1555	photosystem II stabilization
JGK51_RS32405	COG1307	EDD domain protein, DegV family
JGK51_RS32415	COG0495	leucyl-tRNA aminoacylation
JGK51_RS32435	COG0588	phosphoglycerate mutase activity
JGK51_RS32440	COG0799	negative regulation of ribosome biogenesis
JGK51_RS32450	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JGK51_RS32465	COG0501	Belongs to the peptidase M48B family
JGK51_RS32480	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JGK51_RS32490	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JGK51_RS32495	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JGK51_RS32500	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JGK51_RS32505	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JGK51_RS32510	COG0211	Belongs to the bacterial ribosomal protein bL27 family
JGK51_RS32515	COG0261	This protein binds to 23S rRNA in the presence of protein L20
JGK51_RS32530	COG1530	ribonuclease E activity
JGK51_RS32550	COG2837	iron assimilation
JGK51_RS32565	COG0772	Belongs to the SEDS family
JGK51_RS32570	COG0768	penicillin binding
JGK51_RS32585	COG1077	Cell shape determining protein MreB Mrl
JGK51_RS32590	COG0105	UTP biosynthetic process
JGK51_RS32600	COG0285	dihydrofolate synthase activity
JGK51_RS32605	COG0525	valine-tRNA ligase activity
JGK51_RS32615	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JGK51_RS32620	COG0740	serine-type endopeptidase activity
JGK51_RS32625	COG0740	serine-type endopeptidase activity
JGK51_RS32630	COG0544	peptidyl-prolyl cis-trans isomerase activity
JGK51_RS32660	COG3594	Acyltransferase
JGK51_RS32680	COG0698	ribose 5-phosphate isomerase
JGK51_RS32685	COG1113	amino acid transport
JGK51_RS32695	COG1940	carbohydrate kinase activity
JGK51_RS32705	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JGK51_RS32710	COG1116	anion transmembrane transporter activity
JGK51_RS32715	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JGK51_RS32725	COG1113	amino acid transport
JGK51_RS32735	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JGK51_RS32745	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
JGK51_RS32825	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JGK51_RS32895	COG0668	transmembrane transport
JGK51_RS32910	COG1175	transmembrane transport
JGK51_RS32915	COG0395	ABC-type sugar transport system, permease component
JGK51_RS32920	COG1486	melibiose metabolic process
JGK51_RS32935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JGK51_RS33000	COG0629	single-stranded DNA binding
JGK51_RS33030	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JGK51_RS33040	COG2304	oxidoreductase activity
JGK51_RS33105	COG1131	(ABC) transporter
JGK51_RS33120	COG3962	Belongs to the TPP enzyme family
JGK51_RS33125	COG3718	enzyme involved in inositol metabolism
JGK51_RS33135	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JGK51_RS33170	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JGK51_RS33190	COG1129	ABC transporter
JGK51_RS33200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JGK51_RS33205	COG1869	D-ribose catabolic process
JGK51_RS33215	COG4941	Belongs to the sigma-70 factor family
JGK51_RS33255	COG1028	Short-chain dehydrogenase reductase Sdr
JGK51_RS33260	COG0697	spore germination
JGK51_RS33280	COG0673	inositol 2-dehydrogenase activity
JGK51_RS33285	COG1609	Transcriptional regulator
JGK51_RS33305	COG1472	Belongs to the glycosyl hydrolase 3 family
JGK51_RS33355	COG0028	Belongs to the TPP enzyme family
JGK51_RS33380	COG1946	Acyl-CoA thioesterase
JGK51_RS33390	COG1309	transcriptional regulator
JGK51_RS33395	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JGK51_RS33410	COG1960	acyl-CoA dehydrogenase activity
JGK51_RS33445	COG3486	L-lysine 6-monooxygenase (NADPH) activity
JGK51_RS33470	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JGK51_RS33480	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
JGK51_RS33485	COG4977	sequence-specific DNA binding
JGK51_RS33495	COG0589	response to stress
JGK51_RS33545	COG3979	chitinase
JGK51_RS33555	COG0745	RESPONSE REGULATOR receiver
JGK51_RS33580	COG0406	alpha-ribazole phosphatase activity
JGK51_RS33630	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JGK51_RS33640	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JGK51_RS33645	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JGK51_RS33650	COG0765	amino acid transport
JGK51_RS33655	COG0765	amino acid transport
JGK51_RS33660	COG1126	abc transporter atp-binding protein
JGK51_RS33675	COG3397	chitin binding
JGK51_RS33695	COG2186	Transcriptional regulator
JGK51_RS33735	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JGK51_RS33745	COG2188	Transcriptional regulator
JGK51_RS33770	COG0673	inositol 2-dehydrogenase activity
JGK51_RS33775	COG4702	Belongs to the UPF0303 family
JGK51_RS33790	COG0706	membrane insertase activity
JGK51_RS33810	COG3764	Sortase (surface protein transpeptidase)
JGK51_RS33890	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
JGK51_RS33900	COG0071	Belongs to the small heat shock protein (HSP20) family
JGK51_RS33915	COG2733	membrane
JGK51_RS33925	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JGK51_RS33960	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JGK51_RS33975	COG1131	(ABC) transporter
JGK51_RS33990	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
JGK51_RS33995	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JGK51_RS34000	COG1263	PTS System
JGK51_RS34005	COG1263	PTS System
JGK51_RS34045	COG1113	amino acid transport
JGK51_RS34055	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
JGK51_RS34065	COG1335	isochorismatase
JGK51_RS34100	COG0277	FAD linked oxidase domain protein
JGK51_RS34110	COG3185	4-Hydroxyphenylpyruvate dioxygenase
JGK51_RS34190	COG3525	Glycosyl hydrolase, family 20, catalytic domain
JGK51_RS34200	COG1678	Uncharacterized ACR, COG1678
JGK51_RS34205	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JGK51_RS34210	COG0776	regulation of translation
JGK51_RS34220	COG3973	AAA domain
JGK51_RS34230	COG0277	FAD linked oxidase domain protein
JGK51_RS34250	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JGK51_RS34265	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
JGK51_RS34270	COG0793	Belongs to the peptidase S41A family
JGK51_RS34275	COG2177	Part of the ABC transporter FtsEX involved in
JGK51_RS34280	COG2884	Cell division ATP-binding protein ftsE
JGK51_RS34295	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
JGK51_RS34300	COG0515	serine threonine protein kinase
JGK51_RS34305	COG0515	serine threonine protein kinase
JGK51_RS34315	COG1653	transport
JGK51_RS34320	COG1175	transmembrane transport
JGK51_RS34325	COG0395	ABC-type sugar transport system, permease component
JGK51_RS34340	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JGK51_RS34345	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JGK51_RS34355	COG1216	Glycosyl transferase, family 2
JGK51_RS34360	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JGK51_RS34365	COG0463	Glycosyl transferase, family 2
JGK51_RS34365	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JGK51_RS34370	COG1764	response to oxidative stress
JGK51_RS34375	COG1846	Transcriptional regulator
JGK51_RS34390	COG1215	transferase activity, transferring glycosyl groups
JGK51_RS34405	COG1309	transcriptional regulator
JGK51_RS34415	COG1134	teichoic acid transport
JGK51_RS34420	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JGK51_RS34425	COG1215	transferase activity, transferring glycosyl groups
JGK51_RS34435	COG2902	Dehydrogenase
JGK51_RS34460	COG0653	protein targeting
JGK51_RS34470	COG3214	Protein conserved in bacteria
JGK51_RS34475	COG2197	response regulator
JGK51_RS34480	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JGK51_RS34490	COG0823	Involved in the tonB-independent uptake of proteins
JGK51_RS34495	COG5000	phosphorelay sensor kinase activity
JGK51_RS34495	COG5002	protein histidine kinase activity
JGK51_RS34500	COG0745	RESPONSE REGULATOR receiver
JGK51_RS34505	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
JGK51_RS34525	COG0714	Associated with various cellular activities
JGK51_RS34565	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
JGK51_RS34575	COG1482	cell wall glycoprotein biosynthetic process
JGK51_RS34585	COG2835	tetraacyldisaccharide 4'-kinase activity
JGK51_RS34590	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JGK51_RS34635	COG0391	Required for morphogenesis under gluconeogenic growth conditions
JGK51_RS34640	COG0778	Nitroreductase
JGK51_RS34640	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
JGK51_RS34660	COG1316	TRANSCRIPTIONal
JGK51_RS34665	COG1316	TRANSCRIPTIONal
JGK51_RS34670	COG1316	TRANSCRIPTIONal
JGK51_RS34680	COG1316	TRANSCRIPTIONal
JGK51_RS34690	COG1316	TRANSCRIPTIONal
JGK51_RS34710	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
JGK51_RS34735	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JGK51_RS34750	COG2205	protein histidine kinase activity
JGK51_RS34755	COG0745	RESPONSE REGULATOR receiver
JGK51_RS34760	COG3104	oligopeptide transport
JGK51_RS34790	COG1366	Belongs to the anti-sigma-factor antagonist family
JGK51_RS34795	COG1191	sigma factor activity
JGK51_RS34800	COG1228	amidohydrolase
JGK51_RS34810	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JGK51_RS34815	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
JGK51_RS34860	COG0789	Transcriptional regulator
JGK51_RS34875	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JGK51_RS34925	COG2755	lipolytic protein G-D-S-L family
JGK51_RS34930	COG0183	Belongs to the thiolase family
JGK51_RS34960	COG1136	(ABC) transporter
JGK51_RS34960	COG0577	efflux transmembrane transporter activity
JGK51_RS34965	COG0577	efflux transmembrane transporter activity
JGK51_RS34970	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JGK51_RS34975	COG1252	NADH dehydrogenase
JGK51_RS34995	COG0148	phosphopyruvate hydratase activity
JGK51_RS35010	COG1652	LysM domain
JGK51_RS35020	COG2124	cytochrome p450
JGK51_RS35080	COG0577	efflux transmembrane transporter activity
JGK51_RS35085	COG1136	(ABC) transporter
JGK51_RS35115	COG4585	Histidine kinase
JGK51_RS35130	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JGK51_RS35135	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JGK51_RS35140	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
JGK51_RS35145	COG0193	aminoacyl-tRNA hydrolase activity
JGK51_RS35155	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
JGK51_RS35165	COG1309	transcriptional regulator
JGK51_RS35180	COG4106	trans-aconitate 2-methyltransferase activity
JGK51_RS35190	COG2197	response regulator
JGK51_RS35200	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JGK51_RS35240	COG0488	(ABC) transporter
JGK51_RS35250	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
JGK51_RS35255	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
JGK51_RS35265	COG0084	hydrolase, TatD family'
JGK51_RS35315	COG0310	cobalt ion transport
JGK51_RS35325	COG1122	ATPase activity
JGK51_RS35345	COG0442	prolyl-tRNA aminoacylation
JGK51_RS35370	COG2409	Drug exporters of the RND superfamily
JGK51_RS35380	COG0793	Belongs to the peptidase S41A family
JGK51_RS35380	COG4946	Tricorn protease homolog
JGK51_RS35390	COG1028	Short-chain dehydrogenase reductase Sdr
JGK51_RS35395	COG2267	carboxylic ester hydrolase activity
JGK51_RS35400	COG2072	flavoprotein involved in K transport
JGK51_RS35405	COG0789	Transcriptional regulator
JGK51_RS35410	COG0708	Exodeoxyribonuclease III
JGK51_RS35430	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JGK51_RS35435	COG0521	Mo-molybdopterin cofactor biosynthetic process
JGK51_RS35435	COG0315	cyclic pyranopterin monophosphate synthase activity
JGK51_RS35440	COG0315	cyclic pyranopterin monophosphate synthase activity
JGK51_RS35450	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JGK51_RS35455	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JGK51_RS35470	COG0477	Major facilitator Superfamily
JGK51_RS35480	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
JGK51_RS35510	COG1376	ErfK ybiS ycfS ynhG family protein
JGK51_RS35545	COG1247	-acetyltransferase
JGK51_RS35550	COG3384	dioxygenase
JGK51_RS35555	COG1846	Transcriptional regulator
JGK51_RS35585	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JGK51_RS35590	COG4865	methylaspartate mutase activity
JGK51_RS35595	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
JGK51_RS35610	COG1309	transcriptional regulator
JGK51_RS35630	COG1523	belongs to the glycosyl hydrolase 13 family
JGK51_RS35650	COG0640	Transcriptional regulator
JGK51_RS35655	COG0386	Belongs to the glutathione peroxidase family
JGK51_RS35680	COG1686	Belongs to the peptidase S11 family
JGK51_RS35705	COG3629	intracellular signal transduction
JGK51_RS35705	COG3903	Transcriptional regulator
JGK51_RS35715	COG0641	radical SAM
JGK51_RS35745	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
JGK51_RS35760	COG1012	belongs to the aldehyde dehydrogenase family
JGK51_RS35790	COG3629	intracellular signal transduction
JGK51_RS35790	COG3903	Transcriptional regulator
JGK51_RS35820	COG1024	Enoyl-CoA hydratase
JGK51_RS35830	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JGK51_RS35830	COG0515	serine threonine protein kinase
JGK51_RS35840	COG1309	transcriptional regulator
JGK51_RS35845	COG1522	sequence-specific DNA binding
JGK51_RS35850	COG1280	lysine exporter protein (LysE YggA)
JGK51_RS35860	COG1960	acyl-CoA dehydrogenase activity
JGK51_RS35875	COG0259	pyridoxamine-phosphate oxidase activity
JGK51_RS35890	COG2072	flavoprotein involved in K transport
JGK51_RS35900	COG1024	Enoyl-CoA hydratase
JGK51_RS35930	COG1960	acyl-CoA dehydrogenase activity
JGK51_RS35935	COG1028	Short-chain dehydrogenase reductase Sdr
JGK51_RS35950	COG1960	acyl-CoA dehydrogenase activity
JGK51_RS35955	COG1960	acyl-CoA dehydrogenase activity
JGK51_RS35965	COG0318	PFAM AMP-dependent synthetase and ligase
JGK51_RS35990	COG0494	nUDIX hydrolase
JGK51_RS36060	COG1595	DNA-templated transcription, initiation
JGK51_RS36080	COG4821	SIS domain
JGK51_RS36095	COG0259	pyridoxamine-phosphate oxidase activity
JGK51_RS36120	COG0318	PFAM AMP-dependent synthetase and ligase
JGK51_RS36135	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JGK51_RS36170	COG0247	lactate metabolic process
JGK51_RS36170	COG0277	FAD linked oxidase domain protein
JGK51_RS36175	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
JGK51_RS36215	COG0667	Aldo Keto reductase
JGK51_RS36245	COG2252	PERMEase
JGK51_RS36255	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JGK51_RS36280	COG2814	Major facilitator Superfamily
JGK51_RS36290	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JGK51_RS36295	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
JGK51_RS36300	COG1278	Cold shock
JGK51_RS36325	COG1061	Type III restriction enzyme res subunit
JGK51_RS36340	COG3973	AAA domain
JGK51_RS36350	COG2268	Band 7 protein
JGK51_RS36390	COG1737	Transcriptional regulator
JGK51_RS36395	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
JGK51_RS36400	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JGK51_RS36400	COG1263	PTS System
JGK51_RS36415	COG0459	protein refolding
JGK51_RS36420	COG1278	Cold shock
JGK51_RS36430	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
JGK51_RS36435	COG0463	Glycosyl transferase, family 2
JGK51_RS36455	COG1653	transport
JGK51_RS36480	COG3300	MHYT domain
JGK51_RS36480	COG5001	Diguanylate cyclase
JGK51_RS36565	COG2867	negative regulation of translational initiation
JGK51_RS36570	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JGK51_RS36575	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JGK51_RS36590	COG2329	Antibiotic biosynthesis monooxygenase
JGK51_RS36595	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JGK51_RS36615	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JGK51_RS36620	COG1028	Short-chain dehydrogenase reductase Sdr
JGK51_RS36620	COG0604	alcohol dehydrogenase
JGK51_RS36620	COG3321	synthase
JGK51_RS36645	COG3842	ATPase activity
JGK51_RS36655	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JGK51_RS36665	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JGK51_RS36670	COG0215	cysteine-tRNA ligase activity
JGK51_RS36680	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
JGK51_RS36685	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
JGK51_RS36690	COG1329	Transcriptional regulator
JGK51_RS36705	COG5002	protein histidine kinase activity
JGK51_RS36725	COG0640	Transcriptional regulator
JGK51_RS36730	COG0798	PFAM Bile acid sodium symporter
JGK51_RS36735	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JGK51_RS36755	COG1196	nuclear chromosome segregation
JGK51_RS36775	COG0588	phosphoglycerate mutase activity
JGK51_RS36805	COG0438	transferase activity, transferring glycosyl groups
JGK51_RS36815	COG3883	PFAM NLP P60 protein
JGK51_RS36815	COG0791	NLP P60 protein
JGK51_RS36820	COG2204	response regulator
JGK51_RS36840	COG0494	nUDIX hydrolase
JGK51_RS36865	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JGK51_RS36870	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
JGK51_RS36880	COG1309	transcriptional regulator
JGK51_RS36890	COG0546	phosphoglycolate phosphatase activity
JGK51_RS36895	COG2186	Transcriptional regulator
JGK51_RS36905	COG2188	Transcriptional regulator
JGK51_RS36910	COG4552	Acetyltransferase involved in intracellular survival and related
JGK51_RS36920	COG1490	D-aminoacyl-tRNA deacylase activity
JGK51_RS36935	COG3485	protocatechuate 3,4-dioxygenase
JGK51_RS36960	COG2897	thiosulfate sulfurtransferase activity
JGK51_RS36995	COG0745	RESPONSE REGULATOR receiver
JGK51_RS37000	COG1609	Transcriptional regulator
JGK51_RS37005	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JGK51_RS37015	COG0745	RESPONSE REGULATOR receiver
JGK51_RS37025	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JGK51_RS37030	COG0456	acetyltransferase
JGK51_RS37035	COG1725	Transcriptional regulator
JGK51_RS37040	COG1131	(ABC) transporter
JGK51_RS37050	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
JGK51_RS37060	COG0494	nUDIX hydrolase
JGK51_RS37060	COG0406	alpha-ribazole phosphatase activity
JGK51_RS37080	COG1937	Protein conserved in bacteria
JGK51_RS37090	COG0306	phosphate transporter
JGK51_RS37115	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JGK51_RS37135	COG0277	FAD linked oxidase domain protein
JGK51_RS37140	COG0671	phosphoesterase, PA-phosphatase related
JGK51_RS37145	COG0791	NLP P60 protein
JGK51_RS37155	COG1028	Short-chain dehydrogenase reductase Sdr
JGK51_RS37160	COG1028	Short-chain dehydrogenase reductase Sdr
JGK51_RS37255	COG1252	NADH dehydrogenase
JGK51_RS37285	COG0579	oxidoreductase
JGK51_RS37290	COG0220	tRNA (guanine-N7-)-methyltransferase activity
JGK51_RS37300	COG0667	Aldo Keto reductase
JGK51_RS37315	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JGK51_RS37315	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JGK51_RS37320	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JGK51_RS37350	COG0513	Belongs to the DEAD box helicase family
JGK51_RS37395	COG1643	Atp-dependent helicase
JGK51_RS37430	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
JGK51_RS37450	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JGK51_RS37455	COG0047	phosphoribosylformylglycinamidine synthase activity
JGK51_RS37460	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JGK51_RS37495	COG2197	response regulator
JGK51_RS37505	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
JGK51_RS37520	COG0151	Belongs to the GarS family
JGK51_RS37545	COG1028	Short-chain dehydrogenase reductase Sdr
JGK51_RS37575	COG0433	COG0433 Predicted ATPase
JGK51_RS37590	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JGK51_RS37625	COG1191	sigma factor activity
JGK51_RS37630	COG1191	sigma factor activity
JGK51_RS37665	COG3467	pyridoxamine 5'-phosphate
JGK51_RS37675	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
JGK51_RS37680	COG0463	Glycosyl transferase, family 2
JGK51_RS37685	COG2205	protein histidine kinase activity
JGK51_RS37690	COG0745	RESPONSE REGULATOR receiver
JGK51_RS37725	COG2197	response regulator
JGK51_RS37760	COG0318	PFAM AMP-dependent synthetase and ligase
JGK51_RS37765	COG1595	DNA-templated transcription, initiation
JGK51_RS37800	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JGK51_RS37815	COG0653	protein targeting