locus-tag	class	description
CP967_RS00085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CP967_RS00145	COG0456	acetyltransferase
CP967_RS00160	COG1609	Transcriptional regulator
CP967_RS00175	COG1172	Belongs to the binding-protein-dependent transport system permease family
CP967_RS00180	COG1172	Belongs to the binding-protein-dependent transport system permease family
CP967_RS00190	COG1879	ABC-type sugar transport system periplasmic component
CP967_RS00205	COG2160	L-arabinose isomerase activity
CP967_RS00215	COG1309	transcriptional regulator
CP967_RS00240	COG1024	Enoyl-CoA hydratase
CP967_RS00245	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CP967_RS00260	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
CP967_RS00285	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CP967_RS00300	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CP967_RS00305	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CP967_RS00310	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP967_RS00315	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CP967_RS00330	COG0318	PFAM AMP-dependent synthetase and ligase
CP967_RS00340	COG0402	S-adenosylhomocysteine deaminase activity
CP967_RS00345	COG2233	PERMEase
CP967_RS00365	COG0667	Aldo Keto reductase
CP967_RS00385	COG1136	(ABC) transporter
CP967_RS00455	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CP967_RS00485	COG3547	Transposase (IS116 IS110 IS902 family)
CP967_RS00520	COG0395	ABC-type sugar transport system, permease component
CP967_RS00535	COG0366	Alpha amylase catalytic
CP967_RS00540	COG1940	carbohydrate kinase activity
CP967_RS00540	COG1846	Transcriptional regulator
CP967_RS00555	COG3397	chitin binding
CP967_RS00570	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CP967_RS00575	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CP967_RS00585	COG1609	Transcriptional regulator
CP967_RS00595	COG3572	ergothioneine biosynthetic process
CP967_RS00600	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CP967_RS00605	COG0121	glutamine amidotransferase
CP967_RS00610	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
CP967_RS00625	COG2182	Extracellular solute-binding protein
CP967_RS00630	COG3360	Dodecin
CP967_RS00650	COG0596	Alpha beta hydrolase
CP967_RS00670	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CP967_RS00675	COG1053	succinate dehydrogenase
CP967_RS00685	COG0583	DNA-binding transcription factor activity
CP967_RS00750	COG3275	phosphorelay sensor kinase activity
CP967_RS00755	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CP967_RS00805	COG1191	sigma factor activity
CP967_RS00815	COG4251	negative regulation of phosphorylation
CP967_RS00820	COG0784	Response regulator, receiver
CP967_RS00845	COG0596	Alpha beta hydrolase
CP967_RS00865	COG4172	Belongs to the ABC transporter superfamily
CP967_RS00870	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CP967_RS00900	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CP967_RS00910	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CP967_RS00920	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CP967_RS00930	COG0019	diaminopimelate decarboxylase activity
CP967_RS00945	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CP967_RS00965	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CP967_RS01010	COG4709	membrane
CP967_RS01025	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CP967_RS01065	COG2315	Protein conserved in bacteria
CP967_RS01100	COG1595	DNA-templated transcription, initiation
CP967_RS01130	COG2264	protein methyltransferase activity
CP967_RS01145	COG0477	Major facilitator Superfamily
CP967_RS01185	COG0656	L-ascorbic acid biosynthetic process
CP967_RS01190	COG1063	alcohol dehydrogenase
CP967_RS01200	COG2272	Belongs to the type-B carboxylesterase lipase family
CP967_RS01220	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CP967_RS01225	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CP967_RS01230	COG2319	Wd-40 repeat
CP967_RS01230	COG4249	Peptidase C14 caspase catalytic subunit p20
CP967_RS01250	COG2318	DinB family
CP967_RS01280	COG1802	Transcriptional regulator
CP967_RS01290	COG1505	serine-type exopeptidase activity
CP967_RS01365	COG0659	secondary active sulfate transmembrane transporter activity
CP967_RS01370	COG1063	alcohol dehydrogenase
CP967_RS01385	COG2409	Drug exporters of the RND superfamily
CP967_RS01390	COG1846	Transcriptional regulator
CP967_RS01405	COG0702	epimerase
CP967_RS01415	COG2259	Doxx family
CP967_RS01420	COG1902	pentaerythritol trinitrate reductase activity
CP967_RS01420	COG0446	pyridine nucleotide-disulphide oxidoreductase
CP967_RS01465	COG1120	ATPase activity
CP967_RS01470	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP967_RS01475	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP967_RS01480	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CP967_RS01485	COG1028	Short-chain dehydrogenase reductase Sdr
CP967_RS01490	COG1169	isochorismate synthase
CP967_RS01495	COG1021	2,3-dihydroxybenzoate-AMP ligase
CP967_RS01500	COG1535	isochorismatase
CP967_RS01500	COG3433	isochorismatase activity
CP967_RS01505	COG3433	isochorismatase activity
CP967_RS01505	COG1535	isochorismatase
CP967_RS01510	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP967_RS01510	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP967_RS01525	COG2382	esterase
CP967_RS01540	COG0579	oxidoreductase
CP967_RS01555	COG1028	Short-chain dehydrogenase reductase Sdr
CP967_RS01560	COG1132	(ABC) transporter
CP967_RS01570	COG0028	Belongs to the TPP enzyme family
CP967_RS01580	COG1309	transcriptional regulator
CP967_RS01590	COG1022	Amp-dependent synthetase and ligase
CP967_RS01595	COG1250	3-hydroxyacyl-CoA dehydrogenase
CP967_RS01595	COG1024	Enoyl-CoA hydratase
CP967_RS01600	COG0183	Belongs to the thiolase family
CP967_RS01610	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP967_RS01615	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CP967_RS01635	COG1309	transcriptional regulator
CP967_RS01645	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CP967_RS01655	COG2423	ornithine cyclodeaminase activity
CP967_RS01670	COG0494	nUDIX hydrolase
CP967_RS01680	COG1414	Transcriptional regulator
CP967_RS01685	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CP967_RS01695	COG3833	ABC-type maltose transport systems, permease component
CP967_RS01700	COG1653	transport
CP967_RS01710	COG0435	Glutathione S-transferase
CP967_RS01715	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP967_RS01720	COG0431	NADPH-dependent FMN reductase
CP967_RS01725	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP967_RS01730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP967_RS01735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CP967_RS01740	COG1126	abc transporter atp-binding protein
CP967_RS01745	COG0765	amino acid transport
CP967_RS01760	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP967_RS01765	COG0765	amino acid transport
CP967_RS01780	COG1028	Short-chain dehydrogenase reductase Sdr
CP967_RS01805	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CP967_RS01815	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CP967_RS01825	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CP967_RS01830	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CP967_RS01830	COG0519	Catalyzes the synthesis of GMP from XMP
CP967_RS01835	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CP967_RS01840	COG0318	PFAM AMP-dependent synthetase and ligase
CP967_RS01855	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP967_RS01870	COG1733	regulation of RNA biosynthetic process
CP967_RS01895	COG2197	response regulator
CP967_RS01925	COG1672	PFAM Archaeal ATPase
CP967_RS01925	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CP967_RS01950	COG1556	Lactate utilization protein
CP967_RS01955	COG1139	Iron-sulfur cluster binding protein
CP967_RS01960	COG0247	lactate metabolic process
CP967_RS01965	COG1620	l-lactate permease
CP967_RS01970	COG2186	Transcriptional regulator
CP967_RS02000	COG3851	Histidine kinase
CP967_RS02005	COG2197	response regulator
CP967_RS02025	COG0596	Alpha beta hydrolase
CP967_RS02035	COG0789	Transcriptional regulator
CP967_RS02040	COG1819	glycosyl
CP967_RS02075	COG3959	Transketolase, thiamine diphosphate binding domain
CP967_RS02080	COG3958	Transketolase
CP967_RS02105	COG0726	polysaccharide deacetylase
CP967_RS02115	COG0300	oxidoreductase activity
CP967_RS02120	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CP967_RS02130	COG3467	pyridoxamine 5'-phosphate
CP967_RS02175	COG2755	lipolytic protein G-D-S-L family
CP967_RS02185	COG2365	Tyrosine phosphatase family
CP967_RS02210	COG1657	PFAM Prenyltransferase squalene oxidase
CP967_RS02220	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CP967_RS02230	COG1562	ergosterol biosynthetic process
CP967_RS02235	COG1134	teichoic acid transport
CP967_RS02255	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CP967_RS02280	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CP967_RS02290	COG1024	Enoyl-CoA hydratase
CP967_RS02305	COG2183	response to ionizing radiation
CP967_RS02325	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CP967_RS02365	COG4977	sequence-specific DNA binding
CP967_RS02380	COG0789	Transcriptional regulator
CP967_RS02385	COG1024	Enoyl-CoA hydratase
CP967_RS02385	COG1250	3-hydroxyacyl-CoA dehydrogenase
CP967_RS02390	COG0183	Belongs to the thiolase family
CP967_RS02395	COG1960	acyl-CoA dehydrogenase activity
CP967_RS02400	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CP967_RS02405	COG3268	Saccharopine dehydrogenase
CP967_RS02410	COG1515	deoxyribonuclease V activity
CP967_RS02450	COG2226	methyltransferase
CP967_RS02455	COG1132	(ABC) transporter
CP967_RS02550	COG1793	dna ligase
CP967_RS02610	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CP967_RS02660	COG1960	acyl-CoA dehydrogenase activity
CP967_RS02665	COG2124	cytochrome p450
CP967_RS02685	COG3012	SEC-C Motif Domain Protein
CP967_RS02710	COG1486	melibiose metabolic process
CP967_RS02750	COG1846	Transcriptional regulator
CP967_RS02765	COG3485	protocatechuate 3,4-dioxygenase
CP967_RS02770	COG3485	protocatechuate 3,4-dioxygenase
CP967_RS02775	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CP967_RS02780	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CP967_RS02805	COG1940	carbohydrate kinase activity
CP967_RS02835	COG1132	(ABC) transporter
CP967_RS02840	COG1501	Belongs to the glycosyl hydrolase 31 family
CP967_RS02845	COG1472	Belongs to the glycosyl hydrolase 3 family
CP967_RS02855	COG4209	transmembrane transport
CP967_RS02860	COG0395	ABC-type sugar transport system, permease component
CP967_RS02915	COG4221	oxidoreductase activity
CP967_RS02945	COG4608	Belongs to the ABC transporter superfamily
CP967_RS02955	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CP967_RS02990	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP967_RS03000	COG1028	Short-chain dehydrogenase reductase Sdr
CP967_RS03070	COG1595	DNA-templated transcription, initiation
CP967_RS03105	COG0183	Belongs to the thiolase family
CP967_RS03110	COG1309	transcriptional regulator
CP967_RS03120	COG1960	acyl-CoA dehydrogenase activity
CP967_RS03125	COG1024	Enoyl-CoA hydratase
CP967_RS03130	COG1960	acyl-CoA dehydrogenase activity
CP967_RS03135	COG1960	acyl-CoA dehydrogenase activity
CP967_RS03140	COG1960	acyl-CoA dehydrogenase activity
CP967_RS03150	COG1960	acyl-CoA dehydrogenase activity
CP967_RS03155	COG0318	PFAM AMP-dependent synthetase and ligase
CP967_RS03175	COG1028	Short-chain dehydrogenase reductase Sdr
CP967_RS03180	COG3971	2-oxopent-4-enoate hydratase activity
CP967_RS03190	COG0183	Belongs to the thiolase family
CP967_RS03200	COG1960	acyl-CoA dehydrogenase activity
CP967_RS03205	COG2030	dehydratase
CP967_RS03210	COG1960	acyl-CoA dehydrogenase activity
CP967_RS03215	COG0318	PFAM AMP-dependent synthetase and ligase
CP967_RS03230	COG2030	dehydratase
CP967_RS03235	COG1960	acyl-CoA dehydrogenase activity
CP967_RS03240	COG0183	Belongs to the thiolase family
CP967_RS03260	COG3976	FMN-binding domain protein
CP967_RS03260	COG1053	succinate dehydrogenase
CP967_RS03290	COG1053	succinate dehydrogenase
CP967_RS03300	COG1404	Belongs to the peptidase S8 family
CP967_RS03345	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CP967_RS03415	COG0745	RESPONSE REGULATOR receiver
CP967_RS03420	COG5002	protein histidine kinase activity
CP967_RS03435	COG0789	Transcriptional regulator
CP967_RS03470	COG0154	amidase activity
CP967_RS03475	COG3979	chitinase
CP967_RS03480	COG1869	D-ribose catabolic process
CP967_RS03485	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CP967_RS03495	COG1129	ABC transporter
CP967_RS03510	COG1012	belongs to the aldehyde dehydrogenase family
CP967_RS03610	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CP967_RS03630	COG0673	inositol 2-dehydrogenase activity
CP967_RS03640	COG1172	Belongs to the binding-protein-dependent transport system permease family
CP967_RS03645	COG1129	ABC transporter
CP967_RS03655	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CP967_RS03660	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CP967_RS03670	COG0656	L-ascorbic acid biosynthetic process
CP967_RS03675	COG4106	trans-aconitate 2-methyltransferase activity
CP967_RS03685	COG2154	pterin-4-alpha-carbinolamine dehydratase
CP967_RS03695	COG3619	membrane
CP967_RS03715	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CP967_RS03725	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CP967_RS03725	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CP967_RS03740	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CP967_RS03755	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CP967_RS03780	COG1414	Transcriptional regulator
CP967_RS03790	COG4106	trans-aconitate 2-methyltransferase activity
CP967_RS03815	COG0444	Belongs to the ABC transporter superfamily
CP967_RS03820	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CP967_RS03825	COG0601	transmembrane transport
CP967_RS03840	COG1619	proteins homologs of microcin C7 resistance protein MccF
CP967_RS03850	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CP967_RS03855	COG2362	D-Aminopeptidase
CP967_RS03860	COG0667	Aldo Keto reductase
CP967_RS03880	COG0596	Alpha beta hydrolase
CP967_RS03895	COG1250	3-hydroxyacyl-CoA dehydrogenase
CP967_RS03915	COG0604	alcohol dehydrogenase
CP967_RS03920	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP967_RS03920	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP967_RS03925	COG2301	Belongs to the HpcH HpaI aldolase family
CP967_RS03935	COG1960	acyl-CoA dehydrogenase activity
CP967_RS03940	COG0688	phosphatidylethanolamine metabolic process
CP967_RS03970	COG0559	Belongs to the binding-protein-dependent transport system permease family
CP967_RS03990	COG1929	Belongs to the glycerate kinase type-1 family
CP967_RS04005	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CP967_RS04025	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CP967_RS04035	COG1609	Transcriptional regulator
CP967_RS04040	COG3250	beta-galactosidase activity
CP967_RS04050	COG1175	transmembrane transport
CP967_RS04055	COG3833	ABC-type maltose transport systems, permease component
CP967_RS04065	COG2318	DinB family
CP967_RS04075	COG1482	cell wall glycoprotein biosynthetic process
CP967_RS04090	COG4249	Peptidase C14 caspase catalytic subunit p20
CP967_RS04090	COG2319	Wd-40 repeat
CP967_RS04095	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CP967_RS04110	COG0483	inositol monophosphate 1-phosphatase activity
CP967_RS04160	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CP967_RS04165	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CP967_RS04175	COG1028	Short-chain dehydrogenase reductase Sdr
CP967_RS04180	COG2124	cytochrome p450
CP967_RS04210	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CP967_RS04235	COG1028	Short-chain dehydrogenase reductase Sdr
CP967_RS04255	COG0142	geranyltranstransferase activity
CP967_RS04260	COG0095	Lipoate-protein ligase
CP967_RS04265	COG0142	geranyltranstransferase activity
CP967_RS04275	COG2309	aminopeptidase activity
CP967_RS04290	COG2838	Isocitrate dehydrogenase
CP967_RS04335	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CP967_RS04340	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CP967_RS04370	COG2124	cytochrome p450
CP967_RS04375	COG2130	NADP-dependent
CP967_RS04415	COG0405	Gamma-glutamyltransferase
CP967_RS04430	COG0765	amino acid transport
CP967_RS04435	COG0765	amino acid transport
CP967_RS04440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CP967_RS04445	COG1126	abc transporter atp-binding protein
CP967_RS04455	COG1028	Short-chain dehydrogenase reductase Sdr
CP967_RS04475	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CP967_RS04485	COG2182	Extracellular solute-binding protein
CP967_RS04500	COG2267	carboxylic ester hydrolase activity
CP967_RS04515	COG0783	Belongs to the Dps family
CP967_RS04530	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CP967_RS04535	COG1335	isochorismatase
CP967_RS04540	COG2259	Doxx family
CP967_RS04555	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CP967_RS04555	COG2010	Cytochrome c
CP967_RS04575	COG0745	RESPONSE REGULATOR receiver
CP967_RS04665	COG0823	Involved in the tonB-independent uptake of proteins
CP967_RS04675	COG0464	growth
CP967_RS04690	COG1940	carbohydrate kinase activity
CP967_RS04710	COG2188	Transcriptional regulator
CP967_RS04715	COG0673	inositol 2-dehydrogenase activity
CP967_RS04740	COG0656	L-ascorbic acid biosynthetic process
CP967_RS04750	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CP967_RS04755	COG1414	Transcriptional regulator
CP967_RS04760	COG1136	(ABC) transporter
CP967_RS04770	COG4585	Histidine kinase
CP967_RS04775	COG2197	response regulator
CP967_RS04785	COG0746	molybdenum cofactor guanylyltransferase activity
CP967_RS04790	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CP967_RS04860	COG3864	Putative metallopeptidase domain
CP967_RS04895	COG2233	PERMEase
CP967_RS04910	COG2351	hydroxyisourate hydrolase activity
CP967_RS04935	COG3622	Belongs to the hyi family
CP967_RS04940	COG2084	Dehydrogenase
CP967_RS04945	COG0753	catalase activity
CP967_RS04950	COG3960	tartronate-semialdehyde synthase activity
CP967_RS04965	COG0318	PFAM AMP-dependent synthetase and ligase
CP967_RS04970	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CP967_RS04975	COG2197	response regulator
CP967_RS04985	COG0435	Glutathione S-transferase
CP967_RS04990	COG0477	Major facilitator Superfamily
CP967_RS05010	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CP967_RS05030	COG0829	nickel cation binding
CP967_RS05035	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CP967_RS05040	COG0830	nickel cation binding
CP967_RS05045	COG0804	urea catabolic process
CP967_RS05055	COG0831	urea catabolic process
CP967_RS05065	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CP967_RS05065	COG3608	succinylglutamate desuccinylase aspartoacylase
CP967_RS05070	COG2252	PERMEase
CP967_RS05075	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CP967_RS05130	COG0028	Belongs to the TPP enzyme family
CP967_RS05155	COG1162	GTPase activity
CP967_RS05200	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CP967_RS05210	COG0444	Belongs to the ABC transporter superfamily
CP967_RS05220	COG0747	negative chemotaxis
CP967_RS05230	COG3458	cephalosporin-C deacetylase activity
CP967_RS05250	COG2186	Transcriptional regulator
CP967_RS05255	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CP967_RS05265	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
CP967_RS05280	COG0477	Major facilitator Superfamily
CP967_RS05285	COG0183	Belongs to the thiolase family
CP967_RS05290	COG0583	DNA-binding transcription factor activity
CP967_RS05295	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CP967_RS05300	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CP967_RS05305	COG1250	3-hydroxyacyl-CoA dehydrogenase
CP967_RS05330	COG1960	acyl-CoA dehydrogenase activity
CP967_RS05335	COG3284	Transcriptional regulator
CP967_RS05345	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CP967_RS05355	COG0175	sulfate reduction
CP967_RS05360	COG0529	Catalyzes the synthesis of activated sulfate
CP967_RS05385	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CP967_RS05400	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CP967_RS05410	COG1028	Short-chain dehydrogenase reductase Sdr
CP967_RS05445	COG1175	transmembrane transport
CP967_RS05490	COG0318	PFAM AMP-dependent synthetase and ligase
CP967_RS05520	COG1072	(Pantothenic acid kinase))
CP967_RS05525	COG0346	lactoylglutathione lyase activity
CP967_RS05535	COG2197	response regulator
CP967_RS05540	COG4585	Histidine kinase
CP967_RS05545	COG1136	(ABC) transporter
CP967_RS05555	COG0583	DNA-binding transcription factor activity
CP967_RS05560	COG0156	8-amino-7-oxononanoate synthase activity
CP967_RS05565	COG1063	alcohol dehydrogenase
CP967_RS05575	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CP967_RS05575	COG0515	serine threonine protein kinase
CP967_RS05595	COG0477	Major facilitator Superfamily
CP967_RS05625	COG1136	(ABC) transporter
CP967_RS05625	COG0577	efflux transmembrane transporter activity
CP967_RS05630	COG4585	Histidine kinase
CP967_RS05635	COG2197	response regulator
CP967_RS05645	COG2409	Drug exporters of the RND superfamily
CP967_RS05650	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CP967_RS05655	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CP967_RS05695	COG0745	RESPONSE REGULATOR receiver
CP967_RS05700	COG2205	protein histidine kinase activity
CP967_RS05735	COG4152	abc transporter atp-binding protein
CP967_RS05750	COG3220	belongs to the UPF0276 family
CP967_RS05765	COG3253	May function as heme-dependent peroxidase
CP967_RS05770	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CP967_RS05780	COG0446	pyridine nucleotide-disulphide oxidoreductase
CP967_RS05785	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CP967_RS05800	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CP967_RS05805	COG0183	Belongs to the thiolase family
CP967_RS05810	COG1024	Enoyl-CoA hydratase
CP967_RS05810	COG1250	3-hydroxyacyl-CoA dehydrogenase
CP967_RS05825	COG1216	Glycosyl transferase, family 2
CP967_RS05840	COG2089	acid synthase
CP967_RS05855	COG1316	TRANSCRIPTIONal
CP967_RS05865	COG0531	amino acid
CP967_RS05870	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CP967_RS05875	COG4214	carbohydrate transport
CP967_RS05890	COG1940	carbohydrate kinase activity
CP967_RS05895	COG0395	ABC-type sugar transport system, permease component
CP967_RS05900	COG1175	transmembrane transport
CP967_RS05905	COG1653	transport
CP967_RS05920	COG0681	Belongs to the peptidase S26 family
CP967_RS05925	COG1501	Belongs to the glycosyl hydrolase 31 family
CP967_RS05940	COG1175	transmembrane transport
CP967_RS05945	COG0395	ABC-type sugar transport system, permease component
CP967_RS05950	COG2723	6-phospho-beta-galactosidase activity
CP967_RS05965	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CP967_RS05975	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CP967_RS05995	COG1404	Belongs to the peptidase S8 family
CP967_RS06010	COG1674	ftsk spoiiie
CP967_RS06075	COG0477	Major facilitator Superfamily
CP967_RS06085	COG1414	Transcriptional regulator
CP967_RS06090	COG3971	2-oxopent-4-enoate hydratase activity
CP967_RS06095	COG4569	acetaldehyde dehydrogenase (acetylating) activity
CP967_RS06100	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CP967_RS06105	COG2267	carboxylic ester hydrolase activity
CP967_RS06120	COG1414	Transcriptional regulator
CP967_RS06150	COG2267	carboxylic ester hydrolase activity
CP967_RS06155	COG1063	alcohol dehydrogenase
CP967_RS06165	COG2376	Dihydroxyacetone kinase
CP967_RS06175	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CP967_RS06180	COG1309	transcriptional regulator
CP967_RS06190	COG2755	lipolytic protein G-D-S-L family
CP967_RS06195	COG3507	Belongs to the glycosyl hydrolase 43 family
CP967_RS06205	COG0592	DNA-directed DNA polymerase activity
CP967_RS06210	COG0142	geranyltranstransferase activity
CP967_RS06230	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CP967_RS06235	COG2226	methyltransferase
CP967_RS06255	COG2235	arginine
CP967_RS06280	COG0137	argininosuccinate synthase activity
CP967_RS06325	COG2318	DinB family
CP967_RS06360	COG4195	phage-related replication protein
CP967_RS06400	COG1131	(ABC) transporter
CP967_RS06440	COG3903	Transcriptional regulator
CP967_RS06440	COG3629	intracellular signal transduction
CP967_RS06480	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CP967_RS06485	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CP967_RS06490	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CP967_RS06550	COG0489	protein tyrosine kinase activity
CP967_RS06555	COG0297	glycogen (starch) synthase activity
CP967_RS06575	COG1320	monovalent cation:proton antiporter activity
CP967_RS06590	COG0651	ATP synthesis coupled electron transport
CP967_RS06595	COG1006	Multisubunit Na H antiporter MnhC subunit
CP967_RS06600	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CP967_RS06600	COG2111	Na H antiporter
CP967_RS06605	COG3592	Divergent 4Fe-4S mono-cluster
CP967_RS06635	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CP967_RS06645	COG0531	amino acid
CP967_RS06650	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CP967_RS06660	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CP967_RS06670	COG2040	homocysteine
CP967_RS06695	COG1799	cell septum assembly
CP967_RS06730	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CP967_RS06750	COG3585	molybdate ion transport
CP967_RS06775	COG0477	Major facilitator Superfamily
CP967_RS06795	COG1917	Cupin 2, conserved barrel domain protein
CP967_RS06805	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CP967_RS06810	COG0583	DNA-binding transcription factor activity
CP967_RS06830	COG0657	acetylesterase activity
CP967_RS06840	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CP967_RS06975	COG1215	transferase activity, transferring glycosyl groups
CP967_RS06985	COG2072	flavoprotein involved in K transport
CP967_RS07030	COG3251	PFAM MbtH domain protein
CP967_RS07035	COG1414	Transcriptional regulator
CP967_RS07055	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CP967_RS07085	COG2770	Histidine kinase
CP967_RS07085	COG2208	phosphoserine phosphatase activity
CP967_RS07090	COG0488	(ABC) transporter
CP967_RS07105	COG1846	Transcriptional regulator
CP967_RS07135	COG3693	PFAM glycoside hydrolase, family 10
CP967_RS07140	COG2197	response regulator
CP967_RS07145	COG4585	Histidine kinase
CP967_RS07200	COG3629	intracellular signal transduction
CP967_RS07200	COG3903	Transcriptional regulator
CP967_RS07205	COG0477	Major facilitator Superfamily
CP967_RS07265	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CP967_RS07270	COG0531	amino acid
CP967_RS07275	COG0569	domain protein
CP967_RS07305	COG1136	(ABC) transporter
CP967_RS07305	COG4591	ABC-type transport system involved in lipoprotein release permease component
CP967_RS07310	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CP967_RS07315	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CP967_RS07320	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CP967_RS07335	COG0756	dUTP diphosphatase activity
CP967_RS07360	COG2205	protein histidine kinase activity
CP967_RS07365	COG0745	RESPONSE REGULATOR receiver
CP967_RS07375	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CP967_RS07410	COG1435	thymidine kinase activity
CP967_RS07430	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CP967_RS07435	COG1802	Transcriptional regulator
CP967_RS07450	COG1278	Cold shock
CP967_RS07460	COG3655	Transcriptional regulator
CP967_RS07480	COG0612	Peptidase, M16
CP967_RS07485	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CP967_RS07495	COG0372	Belongs to the citrate synthase family
CP967_RS07505	COG0187	DNA topoisomerase II activity
CP967_RS07520	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CP967_RS07525	COG2186	Transcriptional regulator
CP967_RS07530	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CP967_RS07545	COG0514	ATP-dependent DNA helicase (RecQ)
CP967_RS07560	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CP967_RS07590	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CP967_RS07595	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CP967_RS07600	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CP967_RS07635	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CP967_RS07645	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CP967_RS07650	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CP967_RS07660	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CP967_RS07675	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CP967_RS07680	COG2358	TRAP transporter, solute receptor (TAXI family
CP967_RS07685	COG2205	protein histidine kinase activity
CP967_RS07690	COG0745	RESPONSE REGULATOR receiver
CP967_RS07695	COG1126	abc transporter atp-binding protein
CP967_RS07700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CP967_RS07705	COG0765	amino acid transport
CP967_RS07710	COG0765	amino acid transport
CP967_RS07725	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CP967_RS07740	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CP967_RS07775	COG2207	Transcriptional regulator
CP967_RS07775	COG1917	Cupin 2, conserved barrel domain protein
CP967_RS07780	COG1201	RNA secondary structure unwinding
CP967_RS07785	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CP967_RS07800	COG0783	Belongs to the Dps family
CP967_RS07805	COG1396	sequence-specific DNA binding
CP967_RS07810	COG1058	Belongs to the CinA family
CP967_RS07810	COG1546	Belongs to the CinA family
CP967_RS07820	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CP967_RS07830	COG1674	ftsk spoiiie
CP967_RS07840	COG2205	protein histidine kinase activity
CP967_RS07840	COG3437	response regulator, receiver
CP967_RS07840	COG2205	protein histidine kinase activity
CP967_RS07840	COG3850	Histidine kinase
CP967_RS07840	COG4999	Histidine kinase
CP967_RS07840	COG3437	response regulator, receiver
CP967_RS07840	COG4999	Histidine kinase
CP967_RS07840	COG3850	Histidine kinase
CP967_RS07845	COG2208	phosphoserine phosphatase activity
CP967_RS07845	COG2770	Histidine kinase
CP967_RS07880	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CP967_RS07885	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CP967_RS07890	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
CP967_RS07910	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CP967_RS07915	COG0612	Peptidase, M16
CP967_RS07920	COG1185	polyribonucleotide nucleotidyltransferase activity
CP967_RS07925	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CP967_RS07940	COG1674	ftsk spoiiie
CP967_RS07970	COG1404	Belongs to the peptidase S8 family
CP967_RS07995	COG0455	bacterial-type flagellum organization
CP967_RS08000	COG0747	negative chemotaxis
CP967_RS08005	COG0601	transmembrane transport
CP967_RS08010	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CP967_RS08015	COG0444	Belongs to the ABC transporter superfamily
CP967_RS08035	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CP967_RS08040	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CP967_RS08050	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CP967_RS08065	COG0779	Required for maturation of 30S ribosomal subunits
CP967_RS08085	COG0442	prolyl-tRNA aminoacylation
CP967_RS08100	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CP967_RS08105	COG0750	zinc metalloprotease
CP967_RS08110	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CP967_RS08120	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CP967_RS08135	COG2508	Transcriptional regulator
CP967_RS08160	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CP967_RS08165	COG1177	transmembrane transport
CP967_RS08170	COG1176	ABC-type spermidine putrescine transport system, permease component I
CP967_RS08175	COG3842	ATPase activity
CP967_RS08180	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CP967_RS08185	COG1012	belongs to the aldehyde dehydrogenase family
CP967_RS08200	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CP967_RS08215	COG1012	belongs to the aldehyde dehydrogenase family
CP967_RS08225	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CP967_RS08230	COG1136	(ABC) transporter
CP967_RS08250	COG3842	ATPase activity
CP967_RS08265	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CP967_RS08270	COG2226	methyltransferase
CP967_RS08275	COG2188	Transcriptional regulator
CP967_RS08350	COG0233	cytoplasmic translational termination
CP967_RS08355	COG0528	UMP kinase activity
CP967_RS08360	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CP967_RS08365	COG0052	Belongs to the universal ribosomal protein uS2 family
CP967_RS08380	COG1191	sigma factor activity
CP967_RS08560	COG0443	Heat shock 70 kDa protein
CP967_RS08695	COG0792	nuclease activity
CP967_RS08710	COG0681	Belongs to the peptidase S26 family
CP967_RS08715	COG0681	Belongs to the peptidase S26 family
CP967_RS08730	COG0335	large ribosomal subunit rRNA binding
CP967_RS08735	COG0336	Belongs to the RNA methyltransferase TrmD family
CP967_RS08740	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CP967_RS08745	COG1837	Belongs to the UPF0109 family
CP967_RS08750	COG0228	four-way junction DNA binding
CP967_RS08770	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CP967_RS08800	COG0477	Major facilitator Superfamily
CP967_RS08805	COG1196	nuclear chromosome segregation
CP967_RS08820	COG1254	Belongs to the acylphosphatase family
CP967_RS08830	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CP967_RS08835	COG0571	ribonuclease III activity
CP967_RS08840	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CP967_RS08855	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CP967_RS08860	COG0742	ribosomal rna small subunit methyltransferase
CP967_RS08870	COG1461	Dihydroxyacetone kinase
CP967_RS08875	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CP967_RS08880	COG0351	phosphomethylpyrimidine kinase
CP967_RS08900	COG1181	Belongs to the D-alanine--D-alanine ligase family
CP967_RS08905	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CP967_RS08920	COG0776	regulation of translation
CP967_RS08930	COG0066	3-isopropylmalate dehydratase activity
CP967_RS08935	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CP967_RS08940	COG1414	Transcriptional regulator
CP967_RS08975	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CP967_RS08980	COG0179	Fumarylacetoacetate (FAA) hydrolase
CP967_RS08990	COG5002	protein histidine kinase activity
CP967_RS08995	COG2018	Roadblock/LC7 domain
CP967_RS09015	COG2018	Roadblock/LC7 domain
CP967_RS09035	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CP967_RS09040	COG1228	amidohydrolase
CP967_RS09045	COG0789	Transcriptional regulator
CP967_RS09050	COG0667	Aldo Keto reductase
CP967_RS09070	COG3634	alkyl hydroperoxide reductase activity
CP967_RS09095	COG0492	ferredoxin-NADP+ reductase activity
CP967_RS09185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CP967_RS09190	COG0601	transmembrane transport
CP967_RS09195	COG4608	Belongs to the ABC transporter superfamily
CP967_RS09205	COG1609	Transcriptional regulator
CP967_RS09210	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CP967_RS09215	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CP967_RS09220	COG0473	3-isopropylmalate dehydrogenase activity
CP967_RS09230	COG0714	Associated with various cellular activities
CP967_RS09235	COG3552	Protein containing von Willebrand factor type A (VWA) domain
CP967_RS09250	COG1309	transcriptional regulator
CP967_RS09260	COG1012	belongs to the aldehyde dehydrogenase family
CP967_RS09265	COG0506	proline dehydrogenase activity
CP967_RS09270	COG3835	regulator
CP967_RS09275	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CP967_RS09280	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CP967_RS09285	COG0440	acetolactate synthase activity
CP967_RS09305	COG0667	Aldo Keto reductase
CP967_RS09310	COG2133	pyrroloquinoline quinone binding
CP967_RS09315	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CP967_RS09315	COG1672	PFAM Archaeal ATPase
CP967_RS09330	COG2409	Drug exporters of the RND superfamily
CP967_RS09340	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CP967_RS09350	COG0154	amidase activity
CP967_RS09355	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CP967_RS09365	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CP967_RS09375	COG4221	oxidoreductase activity
CP967_RS09395	COG0482	sulfurtransferase activity
CP967_RS09410	COG0515	serine threonine protein kinase
CP967_RS09410	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CP967_RS09430	COG2860	membrane
CP967_RS09435	COG4608	Belongs to the ABC transporter superfamily
CP967_RS09440	COG0444	Belongs to the ABC transporter superfamily
CP967_RS09475	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CP967_RS09480	COG0509	glycine decarboxylation via glycine cleavage system
CP967_RS09485	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CP967_RS09490	COG1760	l-serine dehydratase
CP967_RS09500	COG2723	6-phospho-beta-galactosidase activity
CP967_RS09505	COG0395	ABC-type sugar transport system, permease component
CP967_RS09510	COG1175	transmembrane transport
CP967_RS09515	COG2182	Extracellular solute-binding protein
CP967_RS09560	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
CP967_RS09600	COG1376	ErfK ybiS ycfS ynhG family protein
CP967_RS09605	COG1376	ErfK ybiS ycfS ynhG family protein
CP967_RS09615	COG2197	response regulator
CP967_RS09620	COG4585	Histidine kinase
CP967_RS09630	COG1131	(ABC) transporter
CP967_RS09640	COG1132	(ABC) transporter
CP967_RS09655	COG0058	SHG alpha-glucan phosphorylase activity
CP967_RS09660	COG0366	Alpha amylase catalytic
CP967_RS09665	COG0366	Alpha amylase catalytic
CP967_RS09675	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CP967_RS09690	COG3118	belongs to the thioredoxin family
CP967_RS09700	COG1301	dicarboxylic acid transport
CP967_RS09705	COG3290	protein histidine kinase activity
CP967_RS09710	COG4565	transcriptional regulatory protein
CP967_RS09720	COG0205	6-phosphofructokinase activity
CP967_RS09725	COG0280	phosphate acetyltransferase
CP967_RS09725	COG0857	belongs to the CobB CobQ family
CP967_RS09730	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CP967_RS09770	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP967_RS09770	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP967_RS09825	COG3850	Histidine kinase
CP967_RS09825	COG0642	Histidine kinase
CP967_RS09830	COG0745	RESPONSE REGULATOR receiver
CP967_RS09840	COG0488	(ABC) transporter
CP967_RS09855	COG0183	Belongs to the thiolase family
CP967_RS09910	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
CP967_RS09925	COG1250	3-hydroxyacyl-CoA dehydrogenase
CP967_RS09930	COG1309	transcriptional regulator
CP967_RS09945	COG4585	Histidine kinase
CP967_RS09950	COG2197	response regulator
CP967_RS09965	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CP967_RS09970	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CP967_RS09975	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CP967_RS09980	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CP967_RS09985	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CP967_RS09990	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CP967_RS09995	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CP967_RS10015	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CP967_RS10020	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CP967_RS10030	COG2890	protein-(glutamine-N5) methyltransferase activity
CP967_RS10035	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CP967_RS10040	COG0254	rRNA binding
CP967_RS10045	COG1316	TRANSCRIPTIONal
CP967_RS10060	COG0083	homoserine kinase activity
CP967_RS10065	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CP967_RS10070	COG0460	homoserine dehydrogenase
CP967_RS10075	COG0019	diaminopimelate decarboxylase activity
CP967_RS10080	COG0018	arginyl-trna synthetase
CP967_RS10195	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CP967_RS10205	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CP967_RS10225	COG4585	Histidine kinase
CP967_RS10230	COG2197	response regulator
CP967_RS10240	COG0604	alcohol dehydrogenase
CP967_RS10240	COG3321	synthase
CP967_RS10250	COG0318	PFAM AMP-dependent synthetase and ligase
CP967_RS10275	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CP967_RS10280	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CP967_RS10340	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CP967_RS10365	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CP967_RS10370	COG2815	serine threonine protein kinase
CP967_RS10370	COG0515	serine threonine protein kinase
CP967_RS10440	COG0791	NLP P60 protein
CP967_RS10465	COG5002	protein histidine kinase activity
CP967_RS10485	COG0726	polysaccharide deacetylase
CP967_RS10490	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CP967_RS10500	COG0745	RESPONSE REGULATOR receiver
CP967_RS10505	COG2205	protein histidine kinase activity
CP967_RS10510	COG0508	dehydrogenase complex catalyzes the overall conversion of
CP967_RS10510	COG0567	Dehydrogenase, E1 component
CP967_RS10550	COG0604	alcohol dehydrogenase
CP967_RS10555	COG0281	malic enzyme
CP967_RS10560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CP967_RS10565	COG0765	amino acid transport
CP967_RS10570	COG1126	abc transporter atp-binding protein
CP967_RS10580	COG1595	DNA-templated transcription, initiation
CP967_RS10585	COG4106	trans-aconitate 2-methyltransferase activity
CP967_RS10635	COG0515	serine threonine protein kinase
CP967_RS10635	COG2815	serine threonine protein kinase
CP967_RS10655	COG5640	endopeptidase activity
CP967_RS10675	COG0456	acetyltransferase
CP967_RS10680	COG0142	geranyltranstransferase activity
CP967_RS10685	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CP967_RS10690	COG1959	2 iron, 2 sulfur cluster binding
CP967_RS10750	COG2172	sigma factor antagonist activity
CP967_RS10765	COG1597	lipid kinase activity
CP967_RS10780	COG0363	glucosamine-6-phosphate deaminase activity
CP967_RS10785	COG1472	Belongs to the glycosyl hydrolase 3 family
CP967_RS10790	COG0395	ABC-type sugar transport system, permease component
CP967_RS10800	COG2182	Extracellular solute-binding protein
CP967_RS10805	COG2188	Transcriptional regulator
CP967_RS10830	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CP967_RS10850	COG0242	peptide deformylase activity
CP967_RS10870	COG5662	AntiSigma factor
CP967_RS10875	COG1595	DNA-templated transcription, initiation
CP967_RS10885	COG2135	peptidase activity
CP967_RS10895	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CP967_RS10900	COG1162	GTPase activity
CP967_RS10905	COG2076	Multidrug Resistance protein
CP967_RS10910	COG0483	inositol monophosphate 1-phosphatase activity
CP967_RS10920	COG0753	catalase activity
CP967_RS10945	COG1615	UPF0182 protein
CP967_RS10955	COG3480	Lon protease (S16) C-terminal proteolytic domain
CP967_RS11005	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CP967_RS11045	COG0210	DNA helicase
CP967_RS11100	COG0596	Alpha beta hydrolase
CP967_RS11145	COG1432	Conserved Protein
CP967_RS11150	COG2095	MarC family integral membrane protein
CP967_RS11175	COG0598	Magnesium transport protein CorA
CP967_RS11210	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CP967_RS11215	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CP967_RS11225	COG1595	DNA-templated transcription, initiation
CP967_RS11240	COG1024	Enoyl-CoA hydratase
CP967_RS11245	COG0519	Catalyzes the synthesis of GMP from XMP
CP967_RS11255	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CP967_RS11260	COG1611	Belongs to the LOG family
CP967_RS11265	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CP967_RS11295	COG2912	Transglutaminase-like superfamily
CP967_RS11310	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CP967_RS11330	COG4608	Belongs to the ABC transporter superfamily
CP967_RS11340	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CP967_RS11345	COG0601	transmembrane transport
CP967_RS11350	COG4166	transmembrane transport
CP967_RS11355	COG4608	Belongs to the ABC transporter superfamily
CP967_RS11365	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CP967_RS11370	COG0601	transmembrane transport
CP967_RS11380	COG1217	gtp-binding protein TYPA
CP967_RS11395	COG0463	Glycosyl transferase, family 2
CP967_RS11450	COG1554	hydrolase, family 65, central catalytic
CP967_RS11480	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CP967_RS11510	COG0012	GTP binding
CP967_RS11525	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CP967_RS11535	COG1570	exodeoxyribonuclease VII activity
CP967_RS11540	COG1722	exodeoxyribonuclease VII activity
CP967_RS11545	COG0778	Nitroreductase
CP967_RS11575	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CP967_RS11575	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CP967_RS11580	COG0114	fumarate hydratase activity
CP967_RS11595	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CP967_RS11615	COG1136	(ABC) transporter
CP967_RS11630	COG0450	alkyl hydroperoxide reductase
CP967_RS11635	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CP967_RS11640	COG3654	unkown
CP967_RS11655	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CP967_RS11660	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CP967_RS11665	COG0667	Aldo Keto reductase
CP967_RS11700	COG3135	benzoate transporter
CP967_RS11745	COG2885	chlorophyll binding
CP967_RS11765	COG2197	response regulator
CP967_RS11770	COG4585	Histidine kinase
CP967_RS11800	COG2894	cell division
CP967_RS11855	COG2610	gluconate transmembrane transporter activity
CP967_RS11860	COG0251	oxidation-reduction process
CP967_RS11865	COG1414	Transcriptional regulator
CP967_RS11880	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CP967_RS11910	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
CP967_RS11920	COG1331	Highly conserved protein containing a thioredoxin domain
CP967_RS11930	COG2255	four-way junction helicase activity
CP967_RS11940	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CP967_RS11950	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CP967_RS11965	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CP967_RS11990	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CP967_RS12050	COG1396	sequence-specific DNA binding
CP967_RS12070	COG3420	alginic acid biosynthetic process
CP967_RS12080	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CP967_RS12085	COG1136	(ABC) transporter
CP967_RS12095	COG1376	ErfK ybiS ycfS ynhG family protein
CP967_RS12120	COG1024	Enoyl-CoA hydratase
CP967_RS12135	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CP967_RS12145	COG0424	maF-like protein
CP967_RS12155	COG4770	biotin carboxylase activity
CP967_RS12185	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CP967_RS12200	COG1012	belongs to the aldehyde dehydrogenase family
CP967_RS12205	COG1012	belongs to the aldehyde dehydrogenase family
CP967_RS12220	COG1595	DNA-templated transcription, initiation
CP967_RS12225	COG0745	RESPONSE REGULATOR receiver
CP967_RS12230	COG2205	protein histidine kinase activity
CP967_RS12255	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CP967_RS12265	COG0583	DNA-binding transcription factor activity
CP967_RS12270	COG2814	Major facilitator Superfamily
CP967_RS12290	COG1404	Belongs to the peptidase S8 family
CP967_RS12305	COG1079	Belongs to the binding-protein-dependent transport system permease family
CP967_RS12310	COG4603	Belongs to the binding-protein-dependent transport system permease family
CP967_RS12315	COG3845	ABC transporter
CP967_RS12320	COG1744	ABC transporter substrate-binding protein PnrA-like
CP967_RS12325	COG1473	amidohydrolase
CP967_RS12325	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CP967_RS12330	COG1309	transcriptional regulator
CP967_RS12335	COG1028	Short-chain dehydrogenase reductase Sdr
CP967_RS12355	COG2192	nodulation
CP967_RS12365	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CP967_RS12380	COG2089	acid synthase
CP967_RS12385	COG1083	cytidylyl-transferase
CP967_RS12395	COG1216	Glycosyl transferase, family 2
CP967_RS12425	COG1216	Glycosyl transferase, family 2
CP967_RS12440	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP967_RS12440	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP967_RS12460	COG0386	Belongs to the glutathione peroxidase family
CP967_RS12465	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CP967_RS12470	COG2192	nodulation
CP967_RS12480	COG2890	protein-(glutamine-N5) methyltransferase activity
CP967_RS12500	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CP967_RS12565	COG2062	phosphohistidine phosphatase, SixA
CP967_RS12570	COG1028	Short-chain dehydrogenase reductase Sdr
CP967_RS12575	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CP967_RS12585	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CP967_RS12600	COG1162	GTPase activity
CP967_RS12615	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CP967_RS12625	COG2009	succinate dehydrogenase
CP967_RS12635	COG1053	succinate dehydrogenase
CP967_RS12640	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CP967_RS12650	COG0747	negative chemotaxis
CP967_RS12655	COG1408	metallophosphoesterase
CP967_RS12705	COG1295	ribonuclease BN
CP967_RS12725	COG0180	Tryptophanyl-tRNA synthetase
CP967_RS12730	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CP967_RS12735	COG0754	glutathionylspermidine amidase activity
CP967_RS12745	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CP967_RS12750	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CP967_RS12760	COG0039	L-malate dehydrogenase activity
CP967_RS12770	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CP967_RS12785	COG0138	bifunctional purine biosynthesis protein purh
CP967_RS12815	COG0045	succinate-CoA ligase (ADP-forming) activity
CP967_RS12820	COG3552	Protein containing von Willebrand factor type A (VWA) domain
CP967_RS12830	COG0714	Associated with various cellular activities
CP967_RS12850	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP967_RS12880	COG0791	NLP P60 protein
CP967_RS12885	COG2197	response regulator
CP967_RS12920	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CP967_RS12920	COG0519	Catalyzes the synthesis of GMP from XMP
CP967_RS12940	COG1012	belongs to the aldehyde dehydrogenase family
CP967_RS12945	COG0515	serine threonine protein kinase
CP967_RS12960	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CP967_RS12975	COG0516	GMP reductase activity
CP967_RS12985	COG1595	DNA-templated transcription, initiation
CP967_RS12990	COG2197	response regulator
CP967_RS13000	COG0583	DNA-binding transcription factor activity
CP967_RS13010	COG4221	oxidoreductase activity
CP967_RS13020	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CP967_RS13025	COG0726	polysaccharide deacetylase
CP967_RS13055	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CP967_RS13080	COG0802	atpase or kinase
CP967_RS13090	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CP967_RS13100	COG0736	holo-[acyl-carrier-protein] synthase activity
CP967_RS13105	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CP967_RS13115	COG1072	(Pantothenic acid kinase))
CP967_RS13125	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CP967_RS13130	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CP967_RS13135	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CP967_RS13140	COG0488	(ABC) transporter
CP967_RS13150	COG0101	tRNA pseudouridine synthase activity
CP967_RS13155	COG0203	ribosomal protein L17
CP967_RS13160	COG0202	RNA polymerase activity
CP967_RS13165	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CP967_RS13170	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CP967_RS13175	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CP967_RS13180	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CP967_RS13190	COG0563	adenylate kinase activity
CP967_RS13200	COG0200	Binds to the 23S rRNA
CP967_RS13205	COG1841	ribosomal large subunit assembly
CP967_RS13210	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CP967_RS13215	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CP967_RS13220	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CP967_RS13225	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CP967_RS13235	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CP967_RS13240	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CP967_RS13245	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CP967_RS13250	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CP967_RS13255	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CP967_RS13260	COG0255	Belongs to the universal ribosomal protein uL29 family
CP967_RS13265	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CP967_RS13270	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CP967_RS13275	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CP967_RS13280	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CP967_RS13285	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CP967_RS13290	COG0089	rRNA binding
CP967_RS13295	COG0088	Forms part of the polypeptide exit tunnel
CP967_RS13300	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CP967_RS13305	COG0051	transcription antitermination factor activity, RNA binding
CP967_RS13320	COG3940	Belongs to the glycosyl hydrolase 43 family
CP967_RS13325	COG3507	Belongs to the glycosyl hydrolase 43 family
CP967_RS13370	COG3973	AAA domain
CP967_RS13400	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CP967_RS13405	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CP967_RS13410	COG0049	tRNA binding
CP967_RS13415	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CP967_RS13535	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CP967_RS13540	COG0085	RNA polymerase activity
CP967_RS13550	COG0222	ribosome binding
CP967_RS13555	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CP967_RS13565	COG0081	regulation of translation
CP967_RS13570	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CP967_RS13590	COG0436	Aminotransferase
CP967_RS13595	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CP967_RS13600	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CP967_RS13610	COG2030	dehydratase
CP967_RS13615	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CP967_RS13635	COG0702	epimerase
CP967_RS13645	COG1666	GTP binding
CP967_RS13650	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CP967_RS13655	COG2261	transglycosylase associated protein
CP967_RS13660	COG3304	Inner membrane component domain
CP967_RS13665	COG0501	Belongs to the peptidase M48B family
CP967_RS13670	COG1970	mechanosensitive ion channel activity
CP967_RS13675	COG1007	ATP synthesis coupled electron transport
CP967_RS13685	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CP967_RS13700	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP967_RS13705	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CP967_RS13710	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP967_RS13715	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP967_RS13720	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP967_RS13740	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CP967_RS13740	COG0674	pyruvate-flavodoxin oxidoreductase activity
CP967_RS13745	COG1013	pyruvate-flavodoxin oxidoreductase activity
CP967_RS13750	COG1733	regulation of RNA biosynthetic process
CP967_RS13755	COG0702	epimerase
CP967_RS13775	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CP967_RS13815	COG0561	phosphatase activity
CP967_RS13835	COG0142	geranyltranstransferase activity
CP967_RS13840	COG3104	oligopeptide transport
CP967_RS13870	COG1007	ATP synthesis coupled electron transport
CP967_RS13880	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CP967_RS13885	COG0713	ATP synthesis coupled electron transport
CP967_RS13890	COG0839	Belongs to the complex I subunit 6 family
CP967_RS13895	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP967_RS13900	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CP967_RS13905	COG1034	ATP synthesis coupled electron transport
CP967_RS13910	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CP967_RS13920	COG0649	NAD binding
CP967_RS13925	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP967_RS13930	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP967_RS13960	COG2226	methyltransferase
CP967_RS13985	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CP967_RS13995	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
CP967_RS14005	COG1278	Cold shock
CP967_RS14025	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CP967_RS14025	COG0515	serine threonine protein kinase
CP967_RS14035	COG1309	transcriptional regulator
CP967_RS14045	COG0501	Belongs to the peptidase M48B family
CP967_RS14055	COG2072	flavoprotein involved in K transport
CP967_RS14065	COG2814	Major facilitator Superfamily
CP967_RS14135	COG1131	(ABC) transporter
CP967_RS14155	COG4821	SIS domain
CP967_RS14165	COG0259	pyridoxamine-phosphate oxidase activity
CP967_RS14180	COG1309	transcriptional regulator
CP967_RS14185	COG1024	Enoyl-CoA hydratase
CP967_RS14220	COG0318	PFAM AMP-dependent synthetase and ligase
CP967_RS14235	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CP967_RS14260	COG5006	permease, DMT superfamily
CP967_RS14265	COG0583	DNA-binding transcription factor activity
CP967_RS14270	COG0247	lactate metabolic process
CP967_RS14270	COG0277	FAD linked oxidase domain protein
CP967_RS14275	COG1316	TRANSCRIPTIONal
CP967_RS14280	COG2205	protein histidine kinase activity
CP967_RS14310	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CP967_RS14350	COG2755	lipolytic protein G-D-S-L family
CP967_RS14420	COG2066	Belongs to the glutaminase family
CP967_RS14465	COG3813	Protein conserved in bacteria
CP967_RS14475	COG0577	efflux transmembrane transporter activity
CP967_RS14475	COG1136	(ABC) transporter
CP967_RS14485	COG1937	Protein conserved in bacteria
CP967_RS14495	COG1028	Short-chain dehydrogenase reductase Sdr
CP967_RS14500	COG4585	Histidine kinase
CP967_RS14505	COG2197	response regulator
CP967_RS14515	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CP967_RS14525	COG2267	carboxylic ester hydrolase activity
CP967_RS14545	COG0667	Aldo Keto reductase
CP967_RS14570	COG2252	PERMEase
CP967_RS14580	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CP967_RS14605	COG2814	Major facilitator Superfamily
CP967_RS14615	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CP967_RS14620	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
CP967_RS14625	COG1278	Cold shock
CP967_RS14645	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP967_RS14650	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP967_RS14655	COG1120	ATPase activity
CP967_RS14685	COG1061	Type III restriction enzyme res subunit
CP967_RS14695	COG3973	AAA domain
CP967_RS14710	COG1984	allophanate hydrolase subunit 2
CP967_RS14715	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CP967_RS14720	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CP967_RS14745	COG1737	Transcriptional regulator
CP967_RS14750	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CP967_RS14755	COG1263	PTS System
CP967_RS14755	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CP967_RS14815	COG0463	Glycosyl transferase, family 2
CP967_RS14825	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CP967_RS14825	COG1877	trehalose-phosphatase activity
CP967_RS14865	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CP967_RS14885	COG2197	response regulator
CP967_RS14915	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CP967_RS14930	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CP967_RS14935	COG4566	intracellular signal transduction
CP967_RS14965	COG1028	Short-chain dehydrogenase reductase Sdr
CP967_RS14985	COG0174	glutamine synthetase
CP967_RS14990	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CP967_RS15005	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CP967_RS15010	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CP967_RS15025	COG3842	ATPase activity
CP967_RS15035	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CP967_RS15045	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CP967_RS15050	COG0215	cysteine-tRNA ligase activity
CP967_RS15065	COG0702	epimerase
CP967_RS15085	COG2814	Major facilitator Superfamily
CP967_RS15090	COG0789	Transcriptional regulator
CP967_RS15100	COG0436	Aminotransferase
CP967_RS15105	COG0318	PFAM AMP-dependent synthetase and ligase
CP967_RS15110	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CP967_RS15115	COG0519	Catalyzes the synthesis of GMP from XMP
CP967_RS15115	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CP967_RS15125	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CP967_RS15130	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CP967_RS15150	COG1960	acyl-CoA dehydrogenase activity
CP967_RS15160	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CP967_RS15175	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CP967_RS15180	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CP967_RS15185	COG1329	Transcriptional regulator
CP967_RS15205	COG5002	protein histidine kinase activity
CP967_RS15220	COG0588	phosphoglycerate mutase activity
CP967_RS15250	COG0419	ATPase involved in DNA repair
CP967_RS15280	COG2801	Transposase and inactivated derivatives
CP967_RS15285	COG2801	Transposase and inactivated derivatives
CP967_RS15350	COG0438	transferase activity, transferring glycosyl groups
CP967_RS15395	COG1733	regulation of RNA biosynthetic process
CP967_RS15470	COG3226	Transcriptional regulator
CP967_RS15510	COG4552	Acetyltransferase involved in intracellular survival and related
CP967_RS15525	COG1490	D-aminoacyl-tRNA deacylase activity
CP967_RS15540	COG3485	protocatechuate 3,4-dioxygenase
CP967_RS15605	COG0745	RESPONSE REGULATOR receiver
CP967_RS15610	COG1609	Transcriptional regulator
CP967_RS15615	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CP967_RS15620	COG0745	RESPONSE REGULATOR receiver
CP967_RS15630	COG0823	Involved in the tonB-independent uptake of proteins
CP967_RS15635	COG0737	Belongs to the 5'-nucleotidase family
CP967_RS15645	COG0456	acetyltransferase
CP967_RS15650	COG1725	Transcriptional regulator
CP967_RS15655	COG1131	(ABC) transporter
CP967_RS15675	COG0494	nUDIX hydrolase
CP967_RS15675	COG0406	alpha-ribazole phosphatase activity
CP967_RS15680	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CP967_RS15695	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CP967_RS15700	COG0306	phosphate transporter
CP967_RS15710	COG1937	Protein conserved in bacteria
CP967_RS15730	COG0671	phosphoesterase, PA-phosphatase related
CP967_RS15735	COG0741	lytic transglycosylase activity
CP967_RS15735	COG1196	nuclear chromosome segregation
CP967_RS15735	COG0739	heme binding
CP967_RS15785	COG0667	Aldo Keto reductase
CP967_RS15830	COG1131	(ABC) transporter
CP967_RS15840	COG4585	Histidine kinase
CP967_RS15845	COG2197	response regulator
CP967_RS15870	COG1846	Transcriptional regulator
CP967_RS15885	COG1252	NADH dehydrogenase
CP967_RS15930	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CP967_RS15945	COG1196	nuclear chromosome segregation
CP967_RS15945	COG0741	lytic transglycosylase activity
CP967_RS15945	COG0739	heme binding
CP967_RS15975	COG1309	transcriptional regulator
CP967_RS15980	COG0300	oxidoreductase activity
CP967_RS16000	COG0513	Belongs to the DEAD box helicase family
CP967_RS16010	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CP967_RS16015	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CP967_RS16045	COG0785	Cytochrome C biogenesis protein
CP967_RS16050	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CP967_RS16050	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CP967_RS16060	COG1643	Atp-dependent helicase
CP967_RS16095	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CP967_RS16105	COG3119	arylsulfatase activity
CP967_RS16135	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CP967_RS16140	COG0047	phosphoribosylformylglycinamidine synthase activity
CP967_RS16145	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CP967_RS16165	COG1131	(ABC) transporter
CP967_RS16180	COG2197	response regulator
CP967_RS16190	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CP967_RS16205	COG0151	Belongs to the GarS family
CP967_RS16305	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
CP967_RS16345	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CP967_RS16385	COG1191	sigma factor activity
CP967_RS16390	COG1191	sigma factor activity
CP967_RS16410	COG2353	YceI-like domain
CP967_RS16415	COG3467	pyridoxamine 5'-phosphate
CP967_RS16430	COG0477	Major facilitator Superfamily
CP967_RS16440	COG0745	RESPONSE REGULATOR receiver
CP967_RS16460	COG1595	DNA-templated transcription, initiation
CP967_RS16505	COG0318	PFAM AMP-dependent synthetase and ligase
CP967_RS16510	COG1595	DNA-templated transcription, initiation
CP967_RS16540	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CP967_RS16555	COG0653	protein targeting
CP967_RS16575	COG0006	proline dipeptidase activity
CP967_RS16605	COG2372	response to copper ion
CP967_RS16610	COG2837	iron assimilation
CP967_RS16620	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CP967_RS16625	COG0561	phosphatase activity
CP967_RS16640	COG1131	(ABC) transporter
CP967_RS16650	COG1131	(ABC) transporter
CP967_RS16660	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
CP967_RS16675	COG0561	phosphatase activity
CP967_RS16685	COG4988	ABC transporter
CP967_RS16690	COG1294	oxidase, subunit
CP967_RS16695	COG1271	oxidase subunit
CP967_RS16700	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CP967_RS16705	COG1609	Transcriptional regulator
CP967_RS16710	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CP967_RS16720	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CP967_RS16745	COG0662	Cupin 2, conserved barrel domain protein
CP967_RS16750	COG1950	PFAM Membrane protein of
CP967_RS16755	COG0626	cystathionine gamma-synthase activity
CP967_RS16765	COG2814	Major facilitator Superfamily
CP967_RS16795	COG0305	Participates in initiation and elongation during chromosome replication
CP967_RS16805	COG0534	Mate efflux family protein
CP967_RS16810	COG0359	binds to the 23S rRNA
CP967_RS16815	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CP967_RS16820	COG0629	single-stranded DNA binding
CP967_RS16825	COG0360	Binds together with S18 to 16S ribosomal RNA
CP967_RS16850	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CP967_RS16870	COG0617	tRNA 3'-terminal CCA addition
CP967_RS16885	COG0515	serine threonine protein kinase
CP967_RS16885	COG2815	serine threonine protein kinase
CP967_RS16890	COG1595	DNA-templated transcription, initiation
CP967_RS16900	COG0492	ferredoxin-NADP+ reductase activity
CP967_RS16905	COG3118	belongs to the thioredoxin family
CP967_RS16920	COG1192	Involved in chromosome partitioning
CP967_RS16925	COG0357	Ribosomal RNA small subunit methyltransferase G
CP967_RS16935	COG0706	membrane insertase activity
CP967_RS16940	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CP967_RS16945	COG0594	ribonuclease P activity
CP967_RS16950	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CP967_RS16965	COG0592	DNA-directed DNA polymerase activity
CP967_RS16970	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CP967_RS16975	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CP967_RS16980	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
CP967_RS16990	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CP967_RS17020	COG0515	serine threonine protein kinase
CP967_RS17045	COG0705	Rhomboid family
CP967_RS17045	COG0457	Tetratricopeptide repeat
CP967_RS17070	COG3764	Sortase (surface protein transpeptidase)
CP967_RS17075	COG3764	Sortase (surface protein transpeptidase)
CP967_RS17080	COG0739	heme binding
CP967_RS17095	COG0515	serine threonine protein kinase
CP967_RS17100	COG0768	penicillin binding
CP967_RS17115	COG1716	ATPase activity
CP967_RS17120	COG1716	ATPase activity
CP967_RS17130	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CP967_RS17135	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CP967_RS17150	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CP967_RS17155	COG0436	Aminotransferase
CP967_RS17175	COG2197	response regulator
CP967_RS17180	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CP967_RS17185	COG0066	3-isopropylmalate dehydratase activity
CP967_RS17190	COG0583	DNA-binding transcription factor activity
CP967_RS17230	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CP967_RS17260	COG1522	sequence-specific DNA binding
CP967_RS17280	COG0746	molybdenum cofactor guanylyltransferase activity
CP967_RS17285	COG0303	'Molybdopterin
CP967_RS17290	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CP967_RS17295	COG0604	alcohol dehydrogenase
CP967_RS17295	COG1028	Short-chain dehydrogenase reductase Sdr
CP967_RS17295	COG3321	synthase
CP967_RS17310	COG0515	serine threonine protein kinase
CP967_RS17315	COG0515	serine threonine protein kinase
CP967_RS17335	COG0022	dehydrogenase e1 component
CP967_RS17340	COG0508	dehydrogenase complex catalyzes the overall conversion of
CP967_RS17380	COG2814	Major facilitator Superfamily
CP967_RS17410	COG1362	aminopeptidase activity
CP967_RS17415	COG1960	acyl-CoA dehydrogenase activity
CP967_RS17425	COG1741	Belongs to the pirin family
CP967_RS17440	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CP967_RS17450	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CP967_RS17455	COG0745	RESPONSE REGULATOR receiver
CP967_RS17460	COG2205	protein histidine kinase activity
CP967_RS17505	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP967_RS17510	COG0180	Tryptophanyl-tRNA synthetase
CP967_RS17520	COG2255	four-way junction helicase activity
CP967_RS17555	COG0475	glutathione-regulated potassium exporter activity
CP967_RS17560	COG0490	domain, Protein
CP967_RS17570	COG1280	lysine exporter protein (LysE YggA)
CP967_RS17595	COG1309	transcriptional regulator
CP967_RS17600	COG2267	carboxylic ester hydrolase activity
CP967_RS17610	COG1959	2 iron, 2 sulfur cluster binding
CP967_RS17620	COG1396	sequence-specific DNA binding
CP967_RS17620	COG3800	Transcriptional regulator
CP967_RS17630	COG1595	DNA-templated transcription, initiation
CP967_RS17685	COG1585	Membrane protein implicated in regulation of membrane protease activity
CP967_RS17720	COG1278	Cold shock
CP967_RS17725	COG0513	Belongs to the DEAD box helicase family
CP967_RS17730	COG3594	Acyltransferase
CP967_RS17785	COG0488	(ABC) transporter
CP967_RS17820	COG0738	Major facilitator superfamily
CP967_RS17860	COG0717	Belongs to the dCTP deaminase family
CP967_RS17865	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
CP967_RS17875	COG2181	nitrate reductase activity
CP967_RS17875	COG0247	lactate metabolic process
CP967_RS17885	COG0443	Heat shock 70 kDa protein
CP967_RS17890	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CP967_RS17895	COG0484	heat shock protein binding
CP967_RS17900	COG0789	Transcriptional regulator
CP967_RS17930	COG0542	response to heat
CP967_RS18020	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CP967_RS18030	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CP967_RS18035	COG0456	acetyltransferase
CP967_RS18035	COG1214	PFAM Peptidase M22, glycoprotease
CP967_RS18115	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CP967_RS18130	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CP967_RS18135	COG0191	fructose-bisphosphate aldolase activity
CP967_RS18145	COG3483	tryptophan 2,3-dioxygenase activity
CP967_RS18150	COG3844	kynureninase activity
CP967_RS18170	COG0745	RESPONSE REGULATOR receiver
CP967_RS18175	COG2205	protein histidine kinase activity
CP967_RS18190	COG4585	Histidine kinase
CP967_RS18195	COG2197	response regulator
CP967_RS18200	COG2124	cytochrome p450
CP967_RS18210	COG3559	Exporter of polyketide antibiotics
CP967_RS18215	COG1131	(ABC) transporter
CP967_RS18230	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CP967_RS18235	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CP967_RS18235	COG0515	serine threonine protein kinase
CP967_RS18240	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CP967_RS18270	COG1802	Transcriptional regulator
CP967_RS18285	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CP967_RS18290	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CP967_RS18315	COG1595	DNA-templated transcription, initiation
CP967_RS18335	COG2755	lipolytic protein G-D-S-L family
CP967_RS18340	COG0326	Molecular chaperone. Has ATPase activity
CP967_RS18360	COG0515	serine threonine protein kinase
CP967_RS18375	COG1131	(ABC) transporter
CP967_RS18380	COG1454	alcohol dehydrogenase
CP967_RS18385	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CP967_RS18475	COG1408	metallophosphoesterase
CP967_RS18485	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CP967_RS18500	COG0003	Pfam Anion-transporting ATPase
CP967_RS18525	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CP967_RS18555	COG2267	carboxylic ester hydrolase activity
CP967_RS18565	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CP967_RS18570	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CP967_RS18575	COG0288	reversible hydration of carbon dioxide
CP967_RS18635	COG1205	dead DEAH box helicase
CP967_RS18635	COG1111	helicase
CP967_RS18640	COG1366	Belongs to the anti-sigma-factor antagonist family
CP967_RS18655	COG2890	protein-(glutamine-N5) methyltransferase activity
CP967_RS18665	COG1754	DNA topoisomerase type I activity
CP967_RS18665	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CP967_RS18670	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CP967_RS18675	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CP967_RS18760	COG2124	cytochrome p450
CP967_RS18790	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP967_RS18815	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CP967_RS18815	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CP967_RS18850	COG1012	belongs to the aldehyde dehydrogenase family
CP967_RS18855	COG2318	DinB family
CP967_RS18865	COG0076	glutamate decarboxylase activity
CP967_RS18870	COG0655	NAD(P)H dehydrogenase (quinone) activity
CP967_RS18875	COG0393	Putative heavy-metal-binding
CP967_RS18895	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CP967_RS18900	COG2027	D-alanyl-D-alanine carboxypeptidase
CP967_RS18910	COG0037	tRNA processing
CP967_RS18925	COG0302	gtp cyclohydrolase
CP967_RS18940	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CP967_RS18960	COG1174	glycine betaine transport
CP967_RS18970	COG1732	Glycine betaine
CP967_RS18980	COG0649	NAD binding
CP967_RS18995	COG2197	response regulator
CP967_RS19000	COG0640	Transcriptional regulator
CP967_RS19015	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CP967_RS19020	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CP967_RS19030	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CP967_RS19045	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CP967_RS19070	COG0739	heme binding
CP967_RS19075	COG2205	protein histidine kinase activity
CP967_RS19080	COG0745	RESPONSE REGULATOR receiver
CP967_RS19090	COG1595	DNA-templated transcription, initiation
CP967_RS19095	COG1194	a g-specific adenine glycosylase
CP967_RS19110	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
CP967_RS19130	COG0248	Ppx GppA phosphatase
CP967_RS19135	COG1082	Xylose isomerase domain protein TIM barrel
CP967_RS19150	COG0129	dihydroxy-acid dehydratase activity
CP967_RS19155	COG0515	serine threonine protein kinase
CP967_RS19155	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CP967_RS19160	COG4991	sh3 domain protein
CP967_RS19170	COG2226	methyltransferase
CP967_RS19175	COG0842	Transport permease protein
CP967_RS19175	COG1129	ABC transporter
CP967_RS19185	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CP967_RS19210	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CP967_RS19215	COG2223	nitrite transmembrane transporter activity
CP967_RS19220	COG0123	including yeast histone deacetylase and acetoin utilization protein
CP967_RS19270	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CP967_RS19275	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CP967_RS19280	COG0181	hydroxymethylbilane synthase activity
CP967_RS19285	COG1648	precorrin-2 dehydrogenase activity
CP967_RS19285	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CP967_RS19295	COG0113	porphobilinogen synthase activity
CP967_RS19300	COG2197	response regulator
CP967_RS19305	COG4585	Histidine kinase
CP967_RS19460	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CP967_RS19465	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CP967_RS19480	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CP967_RS19495	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CP967_RS19525	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP967_RS19545	COG0018	arginyl-trna synthetase
CP967_RS19550	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
CP967_RS19570	COG1690	Belongs to the RtcB family
CP967_RS19580	COG1742	UPF0060 membrane protein
CP967_RS19600	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CP967_RS19605	COG0569	domain protein
CP967_RS19605	COG0475	glutathione-regulated potassium exporter activity
CP967_RS19655	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CP967_RS19675	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CP967_RS19680	COG0406	alpha-ribazole phosphatase activity
CP967_RS19690	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CP967_RS19695	COG0785	Cytochrome C biogenesis protein
CP967_RS19700	COG1333	cytochrome c biogenesis protein
CP967_RS19705	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CP967_RS19710	COG1012	belongs to the aldehyde dehydrogenase family
CP967_RS19725	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CP967_RS19730	COG0109	protoheme IX farnesyltransferase activity
CP967_RS19740	COG0163	prenyltransferase activity
CP967_RS19750	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CP967_RS19765	COG1301	dicarboxylic acid transport
CP967_RS19775	COG1309	transcriptional regulator
CP967_RS19785	COG1028	Short-chain dehydrogenase reductase Sdr
CP967_RS19805	COG0768	penicillin binding
CP967_RS19815	COG2161	toxin-antitoxin pair type II binding
CP967_RS19830	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CP967_RS19850	COG0596	Alpha beta hydrolase
CP967_RS19865	COG1819	glycosyl
CP967_RS19885	COG2130	NADP-dependent
CP967_RS19895	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CP967_RS19905	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CP967_RS19935	COG1686	Belongs to the peptidase S11 family
CP967_RS20010	COG1846	Transcriptional regulator
CP967_RS20015	COG3384	dioxygenase
CP967_RS20020	COG1247	-acetyltransferase
CP967_RS20050	COG0243	molybdopterin cofactor binding
CP967_RS20055	COG0437	4 iron, 4 sulfur cluster binding
CP967_RS20080	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CP967_RS20100	COG2366	antibiotic biosynthetic process
CP967_RS20105	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CP967_RS20110	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CP967_RS20120	COG0315	cyclic pyranopterin monophosphate synthase activity
CP967_RS20125	COG0315	cyclic pyranopterin monophosphate synthase activity
CP967_RS20125	COG0521	Mo-molybdopterin cofactor biosynthetic process
CP967_RS20130	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CP967_RS20190	COG2072	flavoprotein involved in K transport
CP967_RS20200	COG1028	Short-chain dehydrogenase reductase Sdr
CP967_RS20210	COG4946	Tricorn protease homolog
CP967_RS20210	COG0793	Belongs to the peptidase S41A family
CP967_RS20220	COG2409	Drug exporters of the RND superfamily
CP967_RS20230	COG0310	cobalt ion transport
CP967_RS20240	COG1122	ATPase activity
CP967_RS20245	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CP967_RS20275	COG0084	hydrolase, TatD family'
CP967_RS20285	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CP967_RS20295	COG0488	(ABC) transporter
CP967_RS20325	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CP967_RS20330	COG2197	response regulator
CP967_RS20335	COG1846	Transcriptional regulator
CP967_RS20340	COG1309	transcriptional regulator
CP967_RS20350	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CP967_RS20360	COG0193	aminoacyl-tRNA hydrolase activity
CP967_RS20365	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CP967_RS20370	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CP967_RS20375	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CP967_RS20390	COG4585	Histidine kinase
CP967_RS20420	COG2252	PERMEase
CP967_RS20435	COG0577	efflux transmembrane transporter activity
CP967_RS20435	COG1136	(ABC) transporter
CP967_RS20440	COG0577	efflux transmembrane transporter activity
CP967_RS20495	COG0515	serine threonine protein kinase
CP967_RS20495	COG2815	serine threonine protein kinase
CP967_RS20510	COG2124	cytochrome p450
CP967_RS20515	COG1652	LysM domain
CP967_RS20525	COG0148	phosphopyruvate hydratase activity
CP967_RS20555	COG1252	NADH dehydrogenase
CP967_RS20560	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CP967_RS20570	COG1136	(ABC) transporter
CP967_RS20570	COG0577	efflux transmembrane transporter activity
CP967_RS20575	COG1136	(ABC) transporter
CP967_RS20580	COG1609	Transcriptional regulator
CP967_RS20590	COG0601	transmembrane transport
CP967_RS20600	COG0444	Belongs to the ABC transporter superfamily
CP967_RS20605	COG4608	Belongs to the ABC transporter superfamily
CP967_RS20645	COG0183	Belongs to the thiolase family
CP967_RS20650	COG2755	lipolytic protein G-D-S-L family
CP967_RS20755	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CP967_RS20770	COG1228	amidohydrolase
CP967_RS20775	COG1191	sigma factor activity
CP967_RS20780	COG1366	Belongs to the anti-sigma-factor antagonist family
CP967_RS20790	COG3104	oligopeptide transport
CP967_RS20795	COG0745	RESPONSE REGULATOR receiver
CP967_RS20800	COG2205	protein histidine kinase activity
CP967_RS20825	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CP967_RS20925	COG1316	TRANSCRIPTIONal
CP967_RS20930	COG1607	acyl-coa hydrolase
CP967_RS20940	COG1473	amidohydrolase
CP967_RS20945	COG0477	Major facilitator Superfamily
CP967_RS20950	COG1316	TRANSCRIPTIONal
CP967_RS20960	COG1316	TRANSCRIPTIONal
CP967_RS20965	COG1316	TRANSCRIPTIONal
CP967_RS20980	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CP967_RS20990	COG0778	Nitroreductase
CP967_RS20990	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
CP967_RS20995	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CP967_RS21040	COG2835	tetraacyldisaccharide 4'-kinase activity
CP967_RS21050	COG1482	cell wall glycoprotein biosynthetic process
CP967_RS21065	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CP967_RS21115	COG0714	Associated with various cellular activities
CP967_RS21135	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CP967_RS21140	COG0745	RESPONSE REGULATOR receiver
CP967_RS21145	COG5002	protein histidine kinase activity
CP967_RS21145	COG5000	phosphorelay sensor kinase activity
CP967_RS21150	COG0823	Involved in the tonB-independent uptake of proteins
CP967_RS21165	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CP967_RS21170	COG2197	response regulator
CP967_RS21180	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CP967_RS21185	COG0653	protein targeting
CP967_RS21205	COG3226	Transcriptional regulator
CP967_RS21215	COG2902	Dehydrogenase
CP967_RS21220	COG1388	LysM domain
CP967_RS21220	COG1134	teichoic acid transport
CP967_RS21230	COG1309	transcriptional regulator
CP967_RS21235	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CP967_RS21240	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CP967_RS21245	COG2226	methyltransferase
CP967_RS21245	COG1073	alpha beta
CP967_RS21255	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CP967_RS21260	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CP967_RS21265	COG0438	transferase activity, transferring glycosyl groups
CP967_RS21270	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CP967_RS21275	COG0395	ABC-type sugar transport system, permease component
CP967_RS21280	COG1175	transmembrane transport
CP967_RS21285	COG1653	transport
CP967_RS21290	COG1674	ftsk spoiiie
CP967_RS21295	COG0515	serine threonine protein kinase
CP967_RS21300	COG0515	serine threonine protein kinase
CP967_RS21305	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CP967_RS21320	COG2884	Cell division ATP-binding protein ftsE
CP967_RS21325	COG2177	Part of the ABC transporter FtsEX involved in
CP967_RS21330	COG0793	Belongs to the peptidase S41A family
CP967_RS21335	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CP967_RS21350	COG2319	Wd-40 repeat
CP967_RS21350	COG4249	Peptidase C14 caspase catalytic subunit p20
CP967_RS21385	COG0583	DNA-binding transcription factor activity
CP967_RS21405	COG2223	nitrite transmembrane transporter activity
CP967_RS21415	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CP967_RS21430	COG3973	AAA domain
CP967_RS21430	COG3973	AAA domain
CP967_RS21445	COG0776	regulation of translation
CP967_RS21450	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CP967_RS21455	COG1678	Uncharacterized ACR, COG1678
CP967_RS21475	COG0395	ABC-type sugar transport system, permease component
CP967_RS21480	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CP967_RS21495	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CP967_RS21590	COG3185	4-Hydroxyphenylpyruvate dioxygenase
CP967_RS21600	COG0277	FAD linked oxidase domain protein
CP967_RS21635	COG1335	isochorismatase
CP967_RS21645	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CP967_RS21655	COG1113	amino acid transport
CP967_RS21685	COG1234	tRNA 3'-trailer cleavage
CP967_RS21690	COG1263	PTS System
CP967_RS21695	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CP967_RS21700	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CP967_RS21710	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CP967_RS21730	COG0477	Major facilitator Superfamily
CP967_RS21755	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CP967_RS21770	COG4555	ABC transporter
CP967_RS21785	COG2733	membrane
CP967_RS21800	COG1349	DNA-binding transcription factor activity
CP967_RS21815	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CP967_RS21865	COG2272	Belongs to the type-B carboxylesterase lipase family
CP967_RS21930	COG0706	membrane insertase activity
CP967_RS21930	COG4455	Protein of avirulence locus involved in temperature-dependent protein secretion
CP967_RS21935	COG0179	Fumarylacetoacetate (FAA) hydrolase
CP967_RS21940	COG4702	Belongs to the UPF0303 family
CP967_RS21945	COG0673	inositol 2-dehydrogenase activity
CP967_RS21990	COG3397	chitin binding
CP967_RS22005	COG1126	abc transporter atp-binding protein
CP967_RS22010	COG0765	amino acid transport
CP967_RS22015	COG0765	amino acid transport
CP967_RS22020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CP967_RS22030	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP967_RS22080	COG0588	phosphoglycerate mutase activity
CP967_RS22120	COG0395	ABC-type sugar transport system, permease component
CP967_RS22160	COG0589	response to stress
CP967_RS22165	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CP967_RS22185	COG1960	acyl-CoA dehydrogenase activity
CP967_RS22200	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CP967_RS22205	COG1309	transcriptional regulator
CP967_RS22225	COG1946	Acyl-CoA thioesterase
CP967_RS22230	COG1960	acyl-CoA dehydrogenase activity
CP967_RS22340	COG0436	Aminotransferase
CP967_RS22350	COG3960	tartronate-semialdehyde synthase activity
CP967_RS22375	COG1472	Belongs to the glycosyl hydrolase 3 family
CP967_RS22405	COG1404	Belongs to the peptidase S8 family
CP967_RS22435	COG0515	serine threonine protein kinase
CP967_RS22490	COG1028	Short-chain dehydrogenase reductase Sdr
CP967_RS22520	COG1609	Transcriptional regulator
CP967_RS22525	COG0673	inositol 2-dehydrogenase activity
CP967_RS22540	COG1733	regulation of RNA biosynthetic process
CP967_RS22560	COG0500	methyltransferase
CP967_RS22575	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CP967_RS22600	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CP967_RS22640	COG3718	enzyme involved in inositol metabolism
CP967_RS22645	COG3962	Belongs to the TPP enzyme family
CP967_RS22675	COG1131	(ABC) transporter
CP967_RS22690	COG3254	rhamnose metabolic process
CP967_RS22710	COG1119	ATPase activity
CP967_RS22715	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CP967_RS22720	COG2186	Transcriptional regulator
CP967_RS22780	COG0629	single-stranded DNA binding
CP967_RS22820	COG2346	COG2346, Truncated hemoglobins
CP967_RS22850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CP967_RS22865	COG1486	melibiose metabolic process
CP967_RS22870	COG0395	ABC-type sugar transport system, permease component
CP967_RS22875	COG1175	transmembrane transport
CP967_RS22885	COG1940	carbohydrate kinase activity
CP967_RS22890	COG0668	transmembrane transport
CP967_RS22925	COG4266	Belongs to the allantoicase family
CP967_RS22955	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CP967_RS22960	COG2211	Major facilitator Superfamily
CP967_RS22965	COG0076	glutamate decarboxylase activity
CP967_RS22970	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CP967_RS22995	COG1113	amino acid transport
CP967_RS23035	COG1113	amino acid transport
CP967_RS23050	COG4552	Acetyltransferase involved in intracellular survival and related
CP967_RS23060	COG0475	glutathione-regulated potassium exporter activity
CP967_RS23070	COG3594	Acyltransferase
CP967_RS23090	COG0544	peptidyl-prolyl cis-trans isomerase activity
CP967_RS23095	COG0740	serine-type endopeptidase activity
CP967_RS23100	COG0740	serine-type endopeptidase activity
CP967_RS23105	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CP967_RS23115	COG0525	valine-tRNA ligase activity
CP967_RS23120	COG0285	dihydrofolate synthase activity
CP967_RS23130	COG0105	UTP biosynthetic process
CP967_RS23135	COG1077	Cell shape determining protein MreB Mrl
CP967_RS23155	COG0772	Belongs to the SEDS family
CP967_RS23175	COG1530	ribonuclease E activity
CP967_RS23180	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CP967_RS23185	COG0673	inositol 2-dehydrogenase activity
CP967_RS23235	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CP967_RS23240	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CP967_RS23245	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CP967_RS23265	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CP967_RS23270	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CP967_RS23280	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CP967_RS23295	COG0501	Belongs to the peptidase M48B family
CP967_RS23305	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CP967_RS23315	COG0799	negative regulation of ribosome biogenesis
CP967_RS23320	COG0588	phosphoglycerate mutase activity
CP967_RS23345	COG0495	leucyl-tRNA aminoacylation
CP967_RS23355	COG1307	EDD domain protein, DegV family
CP967_RS23360	COG1555	photosystem II stabilization
CP967_RS23370	COG2162	N-hydroxyarylamine O-acetyltransferase activity
CP967_RS23375	COG2353	YceI-like domain
CP967_RS23390	COG0268	Binds directly to 16S ribosomal RNA
CP967_RS23395	COG0481	GTPase activity
CP967_RS23430	COG1420	regulation of RNA biosynthetic process
CP967_RS23435	COG0484	heat shock protein binding
CP967_RS23450	COG0537	adenosine 5'-monophosphoramidase activity
CP967_RS23455	COG1234	tRNA 3'-trailer cleavage
CP967_RS23460	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CP967_RS23470	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CP967_RS23470	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CP967_RS23480	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CP967_RS23490	COG2315	Protein conserved in bacteria
CP967_RS23500	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CP967_RS23515	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CP967_RS23525	COG1381	Involved in DNA repair and RecF pathway recombination
CP967_RS23530	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CP967_RS23540	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CP967_RS23545	COG1121	(ABC) transporter
CP967_RS23550	COG0803	Belongs to the bacterial solute-binding protein 9 family
CP967_RS23550	COG3443	Belongs to the bacterial solute-binding protein 9 family
CP967_RS23555	COG0423	glycine-tRNA ligase activity
CP967_RS23570	COG0574	Belongs to the PEP-utilizing enzyme family
CP967_RS23570	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CP967_RS23595	COG2146	nitrite reductase [NAD(P)H] activity
CP967_RS23595	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CP967_RS23600	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CP967_RS23630	COG0431	NADPH-dependent FMN reductase
CP967_RS23635	COG1324	tolerance protein
CP967_RS23640	COG0243	molybdopterin cofactor binding
CP967_RS23645	COG2949	membrane
CP967_RS23655	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CP967_RS23665	COG0358	DNA primase activity
CP967_RS23670	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CP967_RS23685	COG1070	Carbohydrate kinase
CP967_RS23735	COG3629	intracellular signal transduction
CP967_RS23735	COG3903	Transcriptional regulator
CP967_RS23745	COG0825	malonyl-CoA metabolic process
CP967_RS23745	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CP967_RS23750	COG0318	PFAM AMP-dependent synthetase and ligase
CP967_RS23760	COG1522	sequence-specific DNA binding
CP967_RS23780	COG2130	NADP-dependent
CP967_RS23790	COG4214	carbohydrate transport
CP967_RS23825	COG1231	oxidoreductase activity
CP967_RS23850	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CP967_RS23855	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CP967_RS23860	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CP967_RS23875	COG1741	Belongs to the pirin family
CP967_RS23890	COG2770	Histidine kinase
CP967_RS23890	COG2208	phosphoserine phosphatase activity
CP967_RS23920	COG0789	Transcriptional regulator
CP967_RS23925	COG0667	Aldo Keto reductase
CP967_RS23930	COG2197	response regulator
CP967_RS23935	COG4585	Histidine kinase
CP967_RS23955	COG0477	Major facilitator Superfamily
CP967_RS23965	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CP967_RS24010	COG1358	cellular component organization or biogenesis
CP967_RS24055	COG2154	pterin-4-alpha-carbinolamine dehydratase
CP967_RS24210	COG3845	ABC transporter
CP967_RS24225	COG1657	PFAM Prenyltransferase squalene oxidase
CP967_RS24240	COG1309	transcriptional regulator
CP967_RS24245	COG0438	transferase activity, transferring glycosyl groups
CP967_RS24280	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CP967_RS24285	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CP967_RS24300	COG3340	Belongs to the peptidase S51 family
CP967_RS24315	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CP967_RS24320	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CP967_RS24335	COG0800	Aldolase
CP967_RS24340	COG3022	response to hydroperoxide
CP967_RS24360	COG0515	serine threonine protein kinase
CP967_RS24360	COG2815	serine threonine protein kinase
CP967_RS24395	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CP967_RS24415	COG0477	Major facilitator Superfamily
CP967_RS24420	COG3708	Transcriptional regulator
CP967_RS24420	COG2207	Transcriptional regulator
CP967_RS24440	COG0515	serine threonine protein kinase
CP967_RS24440	COG2815	serine threonine protein kinase
CP967_RS24460	COG1028	Short-chain dehydrogenase reductase Sdr
CP967_RS24465	COG3540	Alkaline phosphatase
CP967_RS24475	COG2814	Major facilitator Superfamily
CP967_RS24495	COG1834	amidinotransferase
CP967_RS24525	COG1120	ATPase activity
CP967_RS24530	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP967_RS24535	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CP967_RS24585	COG1994	Peptidase M50
CP967_RS24615	COG4941	Belongs to the sigma-70 factor family
CP967_RS24645	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CP967_RS24650	COG0477	Major facilitator Superfamily
CP967_RS24695	COG0583	DNA-binding transcription factor activity
CP967_RS24720	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CP967_RS24755	COG2814	Major facilitator Superfamily
CP967_RS24760	COG2146	nitrite reductase [NAD(P)H] activity
CP967_RS24765	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CP967_RS24765	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CP967_RS24770	COG2132	Multicopper oxidase
CP967_RS24790	COG0174	glutamine synthetase
CP967_RS24825	COG1309	transcriptional regulator
CP967_RS24830	COG0477	Major facilitator Superfamily
CP967_RS24835	COG2890	protein-(glutamine-N5) methyltransferase activity
CP967_RS24840	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CP967_RS24850	COG1609	Transcriptional regulator
CP967_RS24855	COG2182	Extracellular solute-binding protein
CP967_RS24865	COG0395	ABC-type sugar transport system, permease component
CP967_RS24870	COG0366	Alpha amylase catalytic
CP967_RS24890	COG1335	isochorismatase
CP967_RS24900	COG1595	DNA-templated transcription, initiation
CP967_RS24910	COG1028	Short-chain dehydrogenase reductase Sdr
CP967_RS24920	COG0738	Major facilitator superfamily
CP967_RS24925	COG3226	Transcriptional regulator
CP967_RS24965	COG2197	response regulator
CP967_RS24970	COG4585	Histidine kinase
CP967_RS24975	COG0789	Transcriptional regulator
CP967_RS24980	COG0745	RESPONSE REGULATOR receiver
CP967_RS25030	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CP967_RS25035	COG0321	lipoyl(octanoyl) transferase activity
CP967_RS25070	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CP967_RS25080	COG0508	dehydrogenase complex catalyzes the overall conversion of
CP967_RS25085	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CP967_RS25090	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CP967_RS25100	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CP967_RS25110	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CP967_RS25125	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CP967_RS25130	COG4106	trans-aconitate 2-methyltransferase activity
CP967_RS25150	COG4585	Histidine kinase
CP967_RS25155	COG2197	response regulator
CP967_RS25160	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CP967_RS25185	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CP967_RS25205	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CP967_RS25210	COG1104	cysteine desulfurase activity
CP967_RS25215	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CP967_RS25220	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CP967_RS25230	COG1376	ErfK ybiS ycfS ynhG family protein
CP967_RS25240	COG1845	cytochrome c oxidase, subunit III
CP967_RS25245	COG2010	Cytochrome c
CP967_RS25250	COG0723	plastoquinol--plastocyanin reductase activity
CP967_RS25255	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CP967_RS25260	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CP967_RS25265	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CP967_RS25305	COG0438	transferase activity, transferring glycosyl groups
CP967_RS25325	COG0003	Pfam Anion-transporting ATPase
CP967_RS25335	COG1940	carbohydrate kinase activity
CP967_RS25360	COG4585	Histidine kinase
CP967_RS25365	COG2197	response regulator
CP967_RS25370	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CP967_RS25385	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CP967_RS25395	COG2193	ferroxidase activity
CP967_RS25400	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CP967_RS25405	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CP967_RS25410	COG2815	serine threonine protein kinase
CP967_RS25410	COG0515	serine threonine protein kinase
CP967_RS25415	COG2022	thiamine diphosphate biosynthetic process
CP967_RS25425	COG2022	thiamine diphosphate biosynthetic process
CP967_RS25425	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CP967_RS25445	COG0352	thiamine-phosphate diphosphorylase activity
CP967_RS25460	COG1233	COG1233 Phytoene dehydrogenase and related
CP967_RS25470	COG1309	transcriptional regulator
CP967_RS25475	COG1511	domain protein
CP967_RS25480	COG1716	ATPase activity
CP967_RS25480	COG1131	(ABC) transporter
CP967_RS25480	COG0842	Transport permease protein
CP967_RS25490	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CP967_RS25510	COG0714	Associated with various cellular activities
CP967_RS25520	COG0275	rRNA processing
CP967_RS25530	COG0768	penicillin binding
CP967_RS25535	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CP967_RS25545	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CP967_RS25550	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CP967_RS25560	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CP967_RS25565	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CP967_RS25585	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CP967_RS25590	COG1799	cell septum assembly
CP967_RS25605	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CP967_RS25615	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CP967_RS25665	COG0587	DNA-directed DNA polymerase activity
CP967_RS25675	COG1432	Conserved Protein
CP967_RS25695	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CP967_RS25715	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CP967_RS25720	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CP967_RS25725	COG0131	Imidazoleglycerol-phosphate dehydratase
CP967_RS25730	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CP967_RS25735	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CP967_RS25740	COG0251	oxidation-reduction process
CP967_RS25745	COG0107	imidazoleglycerol-phosphate synthase activity
CP967_RS25755	COG2267	carboxylic ester hydrolase activity
CP967_RS25765	COG2508	Transcriptional regulator
CP967_RS25770	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CP967_RS25780	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CP967_RS25785	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CP967_RS25805	COG0134	indole-3-glycerol-phosphate synthase activity
CP967_RS25815	COG0133	tryptophan synthase activity
CP967_RS25820	COG0159	tryptophan synthase activity
CP967_RS25835	COG3396	Phenylacetate-CoA oxygenase
CP967_RS25840	COG3460	Phenylacetate-CoA oxygenase
CP967_RS25845	COG3396	Phenylacetate-CoA oxygenase
CP967_RS25850	COG2151	metal-sulfur cluster biosynthetic enzyme
CP967_RS25855	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CP967_RS25860	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CP967_RS25865	COG2301	Belongs to the HpcH HpaI aldolase family
CP967_RS25870	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CP967_RS25875	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CP967_RS25905	COG0067	glutamate synthase
CP967_RS25905	COG0070	glutamate synthase
CP967_RS25905	COG0069	glutamate synthase activity
CP967_RS25915	COG0705	Rhomboid family
CP967_RS25925	COG1278	Cold shock
CP967_RS25950	COG1605	Chorismate mutase
CP967_RS25950	COG0287	Prephenate dehydrogenase
CP967_RS25970	COG0737	Belongs to the 5'-nucleotidase family
CP967_RS26010	COG0559	Belongs to the binding-protein-dependent transport system permease family
CP967_RS26020	COG2050	protein possibly involved in aromatic compounds catabolism
CP967_RS26045	COG1643	Atp-dependent helicase
CP967_RS26050	COG2226	methyltransferase
CP967_RS26070	COG0237	dephospho-CoA kinase activity
CP967_RS26100	COG0330	HflC and HflK could
CP967_RS26105	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CP967_RS26115	COG1309	transcriptional regulator
CP967_RS26125	COG0148	phosphopyruvate hydratase activity
CP967_RS26140	COG0436	Aminotransferase
CP967_RS26160	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CP967_RS26165	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CP967_RS26190	COG0804	urea catabolic process
CP967_RS26195	COG0830	nickel cation binding
CP967_RS26200	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CP967_RS26205	COG0829	nickel cation binding
CP967_RS26225	COG0584	glycerophosphoryl diester phosphodiesterase
CP967_RS26235	COG0556	nucleotide-excision repair
CP967_RS26255	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CP967_RS26265	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CP967_RS26275	COG0322	excinuclease ABC activity
CP967_RS26280	COG1660	Displays ATPase and GTPase activities
CP967_RS26285	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CP967_RS26290	COG1481	regulation of sporulation
CP967_RS26295	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CP967_RS26300	COG0126	phosphoglycerate kinase activity
CP967_RS26305	COG0149	triose-phosphate isomerase activity
CP967_RS26310	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CP967_RS26320	COG0166	Belongs to the GPI family
CP967_RS26345	COG1960	acyl-CoA dehydrogenase activity
CP967_RS26365	COG2197	response regulator
CP967_RS26390	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CP967_RS26395	COG0363	glucosamine-6-phosphate deaminase activity
CP967_RS26410	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CP967_RS26415	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CP967_RS26420	COG0109	protoheme IX farnesyltransferase activity
CP967_RS26430	COG1612	heme a metabolic process
CP967_RS26440	COG1131	(ABC) transporter
CP967_RS26455	COG0719	Fe-S assembly protein
CP967_RS26465	COG0396	ATPase activity
CP967_RS26470	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CP967_RS26475	COG0822	iron-sulfur transferase activity
CP967_RS26590	COG2409	Drug exporters of the RND superfamily
CP967_RS26650	COG2171	N-acyltransferase activity
CP967_RS26655	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CP967_RS26690	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CP967_RS26695	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CP967_RS26710	COG1802	Transcriptional regulator
CP967_RS26730	COG0395	ABC-type sugar transport system, permease component
CP967_RS26750	COG1653	transport
CP967_RS26755	COG2755	lipolytic protein G-D-S-L family
CP967_RS26760	COG3866	Pectate lyase
CP967_RS26830	COG0768	penicillin binding
CP967_RS26840	COG1414	Transcriptional regulator
CP967_RS26905	COG1309	transcriptional regulator
CP967_RS26930	COG0702	epimerase
CP967_RS26940	COG1917	Cupin 2, conserved barrel domain protein
CP967_RS26955	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CP967_RS26980	COG1797	cobyrinic acid a,c-diamide synthase activity
CP967_RS27000	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CP967_RS27015	COG0235	Class ii aldolase
CP967_RS27030	COG0488	(ABC) transporter
CP967_RS27040	COG1024	Enoyl-CoA hydratase
CP967_RS27080	COG3387	PFAM Glycoside hydrolase 15-related
CP967_RS27135	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CP967_RS27140	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CP967_RS27155	COG2261	transglycosylase associated protein
CP967_RS27160	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CP967_RS27180	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CP967_RS27190	COG2186	Transcriptional regulator
CP967_RS27195	COG2807	transmembrane transport
CP967_RS27210	COG0560	Phosphoserine phosphatase
CP967_RS27210	COG3830	Belongs to the UPF0237 family
CP967_RS27215	COG0842	Transport permease protein
CP967_RS27215	COG1131	(ABC) transporter
CP967_RS27215	COG1716	ATPase activity
CP967_RS27225	COG4585	Histidine kinase
CP967_RS27230	COG2197	response regulator
CP967_RS27240	COG1119	ATPase activity
CP967_RS27265	COG1881	PFAM PEBP family protein
CP967_RS27275	COG2094	Belongs to the DNA glycosylase MPG family
CP967_RS27310	COG0647	UMP catabolic process
CP967_RS27315	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP967_RS27320	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP967_RS27325	COG1120	ATPase activity
CP967_RS27345	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CP967_RS27350	COG0497	DNA recombination
CP967_RS27375	COG3387	PFAM Glycoside hydrolase 15-related
CP967_RS27380	COG0504	CTP synthase activity
CP967_RS27385	COG0494	nUDIX hydrolase
CP967_RS27395	COG0686	Belongs to the AlaDH PNT family
CP967_RS27410	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CP967_RS27415	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CP967_RS27420	COG1187	pseudouridine synthase activity
CP967_RS27435	COG0494	nUDIX hydrolase
CP967_RS27460	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CP967_RS27470	COG1160	GTP binding
CP967_RS27485	COG0438	transferase activity, transferring glycosyl groups
CP967_RS27495	COG0671	phosphoesterase, PA-phosphatase related
CP967_RS27500	COG0477	Major facilitator Superfamily
CP967_RS27505	COG1960	acyl-CoA dehydrogenase activity
CP967_RS27510	COG1799	cell septum assembly
CP967_RS27540	COG0641	radical SAM
CP967_RS27550	COG3903	Transcriptional regulator
CP967_RS27550	COG3629	intracellular signal transduction
CP967_RS27575	COG0714	Associated with various cellular activities
CP967_RS27595	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP967_RS27595	COG1028	Short-chain dehydrogenase reductase Sdr
CP967_RS27595	COG3321	synthase
CP967_RS27595	COG0300	oxidoreductase activity
CP967_RS27595	COG0318	PFAM AMP-dependent synthetase and ligase
CP967_RS27610	COG0235	Class ii aldolase
CP967_RS27625	COG0561	phosphatase activity
CP967_RS27630	COG1960	acyl-CoA dehydrogenase activity
CP967_RS27645	COG3540	Alkaline phosphatase
CP967_RS27650	COG0346	lactoylglutathione lyase activity
CP967_RS27655	COG1028	Short-chain dehydrogenase reductase Sdr
CP967_RS27665	COG1725	Transcriptional regulator
CP967_RS27685	COG2188	Transcriptional regulator
CP967_RS27690	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CP967_RS27695	COG1309	transcriptional regulator
CP967_RS27700	COG0243	molybdopterin cofactor binding
CP967_RS27720	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CP967_RS27730	COG1017	nitric oxide dioxygenase activity
CP967_RS27730	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CP967_RS27735	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CP967_RS27740	COG2267	carboxylic ester hydrolase activity
CP967_RS27765	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CP967_RS27785	COG0640	Transcriptional regulator
CP967_RS27795	COG1960	acyl-CoA dehydrogenase activity
CP967_RS27830	COG3876	Protein conserved in bacteria
CP967_RS27835	COG1028	Short-chain dehydrogenase reductase Sdr
CP967_RS27840	COG0318	PFAM AMP-dependent synthetase and ligase
CP967_RS27850	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CP967_RS27855	COG1960	acyl-CoA dehydrogenase activity
CP967_RS27865	COG4948	Mandelate Racemase Muconate Lactonizing
CP967_RS27880	COG2149	membrane
CP967_RS27885	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CP967_RS27895	COG3573	Dehydrogenase
CP967_RS27915	COG3265	gluconokinase activity
CP967_RS27920	COG2186	Transcriptional regulator
CP967_RS27935	COG0564	pseudouridine synthase activity
CP967_RS27945	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CP967_RS27975	COG0667	Aldo Keto reductase
CP967_RS27980	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP967_RS27990	COG0598	Magnesium transport protein CorA
CP967_RS28010	COG0215	cysteine-tRNA ligase activity
CP967_RS28020	COG4948	Mandelate Racemase Muconate Lactonizing
CP967_RS28025	COG1028	Short-chain dehydrogenase reductase Sdr
CP967_RS28030	COG2186	Transcriptional regulator
CP967_RS28035	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CP967_RS28040	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CP967_RS28045	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CP967_RS28050	COG1414	Transcriptional regulator
CP967_RS28055	COG0646	methionine synthase
CP967_RS28055	COG1410	methionine synthase
CP967_RS28060	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CP967_RS28070	COG2197	response regulator
CP967_RS28080	COG0517	IMP dehydrogenase activity
CP967_RS28080	COG1994	Peptidase M50
CP967_RS28105	COG1222	aaa ATPase
CP967_RS28110	COG4122	O-methyltransferase activity
CP967_RS28125	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CP967_RS28130	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CP967_RS28135	COG1609	Transcriptional regulator
CP967_RS28145	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CP967_RS28150	COG0545	Peptidyl-prolyl cis-trans isomerase
CP967_RS28160	COG2378	regulation of single-species biofilm formation
CP967_RS28180	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CP967_RS28185	COG0805	protein transport
CP967_RS28215	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CP967_RS28235	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CP967_RS28240	COG4175	Glycine betaine
CP967_RS28240	COG0517	IMP dehydrogenase activity
CP967_RS28245	COG4176	ABC-type proline glycine betaine transport system permease component
CP967_RS28265	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CP967_RS28275	COG0174	glutamine synthetase
CP967_RS28280	COG1012	belongs to the aldehyde dehydrogenase family
CP967_RS28320	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CP967_RS28325	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CP967_RS28330	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CP967_RS28335	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CP967_RS28340	COG5002	protein histidine kinase activity
CP967_RS28345	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CP967_RS28350	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CP967_RS28350	COG0072	phenylalanine-tRNA ligase activity
CP967_RS28370	COG1649	PFAM Uncharacterised BCR, COG1649
CP967_RS28390	COG0697	spore germination
CP967_RS28420	COG1595	DNA-templated transcription, initiation
CP967_RS28425	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CP967_RS28455	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CP967_RS28460	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CP967_RS28465	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CP967_RS28470	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CP967_RS28475	COG1438	arginine binding
CP967_RS28485	COG0165	Argininosuccinate lyase
CP967_RS28505	COG0477	Major facilitator Superfamily
CP967_RS28515	COG0584	glycerophosphoryl diester phosphodiesterase
CP967_RS28545	COG2011	ABC-type metal ion transport system permease component
CP967_RS28550	COG1464	Belongs to the NlpA lipoprotein family
CP967_RS28565	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CP967_RS28570	COG1648	precorrin-2 dehydrogenase activity
CP967_RS28570	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CP967_RS28575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CP967_RS28630	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CP967_RS28640	COG0456	acetyltransferase
CP967_RS28655	COG1609	Transcriptional regulator
CP967_RS28690	COG1175	transmembrane transport
CP967_RS28695	COG0395	ABC-type sugar transport system, permease component
CP967_RS28725	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CP967_RS28730	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CP967_RS28755	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CP967_RS28760	COG1560	Kdo2-lipid A biosynthetic process
CP967_RS28765	COG0438	transferase activity, transferring glycosyl groups
CP967_RS28775	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CP967_RS28780	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CP967_RS28785	COG0217	transcriptional regulatory protein
CP967_RS28790	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CP967_RS28795	COG0632	four-way junction helicase activity
CP967_RS28800	COG2255	four-way junction helicase activity
CP967_RS28810	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CP967_RS28815	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CP967_RS28820	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CP967_RS28825	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CP967_RS28830	COG1196	nuclear chromosome segregation
CP967_RS28835	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CP967_RS28845	COG0124	histidyl-tRNA synthetase
CP967_RS28865	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CP967_RS28880	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CP967_RS28885	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CP967_RS28900	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CP967_RS28905	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CP967_RS28910	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CP967_RS28915	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CP967_RS28925	COG0006	proline dipeptidase activity
CP967_RS28930	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CP967_RS28935	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CP967_RS28945	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CP967_RS28950	COG0540	Belongs to the ATCase OTCase family
CP967_RS28955	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CP967_RS28965	COG0505	Belongs to the CarA family
CP967_RS28970	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CP967_RS28975	COG0167	dihydroorotate dehydrogenase activity
CP967_RS28980	COG0284	orotidine-5'-phosphate decarboxylase activity
CP967_RS28995	COG1758	RNA polymerase activity
CP967_RS29005	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CP967_RS29020	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CP967_RS29030	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CP967_RS29035	COG2390	Transcriptional regulator
CP967_RS29050	COG1012	belongs to the aldehyde dehydrogenase family
CP967_RS29060	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CP967_RS29075	COG2233	PERMEase
CP967_RS29080	COG2223	nitrite transmembrane transporter activity
CP967_RS29085	COG1940	carbohydrate kinase activity
CP967_RS29085	COG1846	Transcriptional regulator
CP967_RS29105	COG3201	nicotinamide mononucleotide transporter
CP967_RS29110	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CP967_RS29110	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CP967_RS29115	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CP967_RS29120	COG0140	phosphoribosyl-ATP diphosphatase activity
CP967_RS29125	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CP967_RS29165	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CP967_RS29170	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CP967_RS29220	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CP967_RS29250	COG1028	Short-chain dehydrogenase reductase Sdr
CP967_RS29255	COG2015	COG2015, Alkyl sulfatase and related hydrolases
CP967_RS29260	COG2326	polyphosphate kinase activity
CP967_RS29280	COG0529	Catalyzes the synthesis of activated sulfate
CP967_RS29300	COG1028	Short-chain dehydrogenase reductase Sdr
CP967_RS29315	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CP967_RS29325	COG2271	Major facilitator Superfamily
CP967_RS29330	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CP967_RS29340	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CP967_RS29345	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CP967_RS29355	COG2890	protein-(glutamine-N5) methyltransferase activity
CP967_RS29385	COG1960	acyl-CoA dehydrogenase activity
CP967_RS29405	COG1216	Glycosyl transferase, family 2
CP967_RS29410	COG3030	protein affecting phage T7 exclusion by the F plasmid
CP967_RS29420	COG2270	Major facilitator Superfamily
CP967_RS29430	COG2364	Membrane
CP967_RS29435	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CP967_RS29500	COG2018	Roadblock/LC7 domain
CP967_RS29520	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
CP967_RS29535	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CP967_RS29545	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CP967_RS29580	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CP967_RS29600	COG1716	ATPase activity
CP967_RS29620	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CP967_RS29630	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CP967_RS29630	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CP967_RS29665	COG2318	DinB family
CP967_RS29690	COG1695	Transcriptional regulator
CP967_RS29700	COG3547	Transposase (IS116 IS110 IS902 family)
CP967_RS29720	COG0697	spore germination
CP967_RS29745	COG1028	Short-chain dehydrogenase reductase Sdr
CP967_RS29755	COG0179	Fumarylacetoacetate (FAA) hydrolase
CP967_RS29770	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CP967_RS29780	COG0179	Fumarylacetoacetate (FAA) hydrolase
CP967_RS29790	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP967_RS29800	COG1028	Short-chain dehydrogenase reductase Sdr
CP967_RS29825	COG0640	Transcriptional regulator
CP967_RS29870	COG4249	Peptidase C14 caspase catalytic subunit p20
CP967_RS29870	COG2319	Wd-40 repeat
CP967_RS29920	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CP967_RS29930	COG2318	DinB family
CP967_RS29945	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CP967_RS29955	COG0243	molybdopterin cofactor binding
CP967_RS29960	COG2755	lipolytic protein G-D-S-L family
CP967_RS29970	COG1136	(ABC) transporter
CP967_RS30000	COG1968	undecaprenyl-diphosphatase activity
CP967_RS30010	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CP967_RS30055	COG1832	CoA-binding protein
CP967_RS30060	COG1739	Uncharacterized protein family UPF0029
CP967_RS30065	COG0420	3'-5' exonuclease activity
CP967_RS30070	COG0419	ATPase involved in DNA repair
CP967_RS30075	COG1522	sequence-specific DNA binding
CP967_RS30100	COG0626	cystathionine gamma-synthase activity
CP967_RS30115	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CP967_RS30125	COG1595	DNA-templated transcription, initiation
CP967_RS30135	COG1940	carbohydrate kinase activity
CP967_RS30145	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CP967_RS30185	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CP967_RS30190	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CP967_RS30195	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CP967_RS30200	COG0156	8-amino-7-oxononanoate synthase activity
CP967_RS30220	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CP967_RS30240	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CP967_RS30245	COG1140	nitrate reductase beta subunit
CP967_RS30265	COG0740	serine-type endopeptidase activity
CP967_RS30275	COG0831	urea catabolic process
CP967_RS30280	COG0832	Belongs to the urease beta subunit family
CP967_RS30285	COG0804	urea catabolic process
CP967_RS30290	COG0830	nickel cation binding
CP967_RS30295	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CP967_RS30300	COG0829	nickel cation binding
CP967_RS30315	COG0204	Acyl-transferase
CP967_RS30325	COG0205	6-phosphofructokinase activity
CP967_RS30330	COG3442	glutamine amidotransferase
CP967_RS30340	COG0242	peptide deformylase activity
CP967_RS30350	COG1960	acyl-CoA dehydrogenase activity
CP967_RS30355	COG0386	Belongs to the glutathione peroxidase family
CP967_RS30375	COG1946	Acyl-CoA thioesterase
CP967_RS30390	COG1793	dna ligase
CP967_RS30400	COG1132	(ABC) transporter
CP967_RS30405	COG1132	(ABC) transporter
CP967_RS30410	COG0277	FAD linked oxidase domain protein
CP967_RS30420	COG1132	(ABC) transporter
CP967_RS30435	COG0432	Pfam Uncharacterised protein family UPF0047
CP967_RS30465	COG1309	transcriptional regulator
CP967_RS30480	COG1309	transcriptional regulator
CP967_RS30490	COG1309	transcriptional regulator
CP967_RS30500	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CP967_RS30505	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CP967_RS30530	COG2197	response regulator
CP967_RS30545	COG0604	alcohol dehydrogenase
CP967_RS30545	COG3321	synthase
CP967_RS30545	COG1028	Short-chain dehydrogenase reductase Sdr
CP967_RS30600	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CP967_RS30630	COG2226	methyltransferase
CP967_RS30640	COG0583	DNA-binding transcription factor activity
CP967_RS30680	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CP967_RS30685	COG0318	PFAM AMP-dependent synthetase and ligase
CP967_RS30710	COG0673	inositol 2-dehydrogenase activity
CP967_RS30720	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CP967_RS30750	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CP967_RS30770	COG0183	Belongs to the thiolase family
CP967_RS30785	COG1414	Transcriptional regulator
CP967_RS30835	COG2815	serine threonine protein kinase
CP967_RS30835	COG0515	serine threonine protein kinase
CP967_RS30850	COG2706	6-phosphogluconolactonase activity
CP967_RS30865	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CP967_RS30875	COG1609	Transcriptional regulator
CP967_RS30885	COG1175	transmembrane transport
CP967_RS30895	COG1472	Belongs to the glycosyl hydrolase 3 family
CP967_RS31365	COG0640	Transcriptional regulator
CP967_RS31385	COG0671	phosphoesterase, PA-phosphatase related
CP967_RS31410	COG0584	glycerophosphoryl diester phosphodiesterase
CP967_RS31450	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CP967_RS31485	COG0702	epimerase
CP967_RS31505	COG0492	ferredoxin-NADP+ reductase activity
CP967_RS31550	COG2814	Major facilitator Superfamily
CP967_RS31555	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CP967_RS31580	COG0445	tRNA wobble uridine modification
CP967_RS31600	COG2223	nitrite transmembrane transporter activity
CP967_RS31605	COG1940	carbohydrate kinase activity
CP967_RS31640	COG0384	phenazine biosynthesis protein PhzF
CP967_RS31710	COG1349	DNA-binding transcription factor activity
CP967_RS31720	COG0464	growth
CP967_RS31785	COG0789	Transcriptional regulator
CP967_RS31790	COG0515	serine threonine protein kinase
CP967_RS31790	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CP967_RS31795	COG0515	serine threonine protein kinase
CP967_RS31795	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CP967_RS31800	COG2814	Major facilitator Superfamily
CP967_RS31820	COG2375	cellular response to nickel ion
CP967_RS31825	COG0385	Bile acid
CP967_RS31920	COG0477	Major facilitator Superfamily
CP967_RS31925	COG0753	catalase activity
CP967_RS31940	COG0697	spore germination
CP967_RS31955	COG0477	Major facilitator Superfamily
CP967_RS31985	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CP967_RS31990	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CP967_RS31990	COG0723	plastoquinol--plastocyanin reductase activity
CP967_RS32010	COG2985	domain, Protein
CP967_RS32030	COG1175	transmembrane transport
CP967_RS32035	COG0395	ABC-type sugar transport system, permease component
CP967_RS32040	COG3290	protein histidine kinase activity
CP967_RS32045	COG1073	alpha beta
CP967_RS32045	COG2226	methyltransferase
CP967_RS32070	COG0328	RNA-DNA hybrid ribonuclease activity
CP967_RS32080	COG3401	FG-GAP repeat protein
CP967_RS32125	COG0366	Alpha amylase catalytic
CP967_RS32125	COG1874	Beta-galactosidase
CP967_RS32135	COG4209	transmembrane transport
CP967_RS32195	COG0254	rRNA binding
CP967_RS32220	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP967_RS32225	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CP967_RS32240	COG2084	Dehydrogenase
CP967_RS32250	COG1191	sigma factor activity
CP967_RS32265	COG2267	carboxylic ester hydrolase activity
CP967_RS32275	COG0488	(ABC) transporter
CP967_RS32290	COG1461	Dihydroxyacetone kinase
CP967_RS32325	COG0142	geranyltranstransferase activity
CP967_RS32330	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CP967_RS32365	COG2304	oxidoreductase activity
CP967_RS32405	COG1335	isochorismatase
CP967_RS32425	COG3383	formate dehydrogenase (NAD+) activity
CP967_RS32425	COG0243	molybdopterin cofactor binding
CP967_RS32430	COG0437	4 iron, 4 sulfur cluster binding
CP967_RS32445	COG2080	2 iron, 2 sulfur cluster binding
CP967_RS32450	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CP967_RS32455	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CP967_RS32470	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
CP967_RS32480	COG2356	endonuclease I
CP967_RS32490	COG2813	Specifically methylates the guanine in position
CP967_RS32500	COG0515	serine threonine protein kinase
CP967_RS32520	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CP967_RS32525	COG0387	Pfam Sodium calcium exchanger
CP967_RS32530	COG0318	PFAM AMP-dependent synthetase and ligase
CP967_RS32565	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CP967_RS32570	COG2867	negative regulation of translational initiation
CP967_RS32620	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CP967_RS32630	COG5297	Belongs to the glycosyl hydrolase family 6
CP967_RS32635	COG4733	cellulase activity
CP967_RS32635	COG5297	Belongs to the glycosyl hydrolase family 6
CP967_RS32640	COG2318	DinB family
CP967_RS32645	COG0596	Alpha beta hydrolase
CP967_RS32695	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CP967_RS32700	COG1216	Glycosyl transferase, family 2
CP967_RS32705	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CP967_RS32720	COG1683	Conserved Protein
CP967_RS32745	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CP967_RS32755	COG0798	PFAM Bile acid sodium symporter
CP967_RS32760	COG0659	secondary active sulfate transmembrane transporter activity
CP967_RS32765	COG0789	Transcriptional regulator
CP967_RS32770	COG0640	Transcriptional regulator
CP967_RS32810	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CP967_RS32825	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CP967_RS32835	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CP967_RS32845	COG0583	DNA-binding transcription factor activity
CP967_RS32865	COG0714	Associated with various cellular activities
CP967_RS32875	COG4166	transmembrane transport
CP967_RS32890	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CP967_RS32900	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CP967_RS32925	COG1122	ATPase activity
CP967_RS32935	COG1930	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
CP967_RS32940	COG0310	cobalt ion transport
CP967_RS32945	COG1132	(ABC) transporter
CP967_RS32970	COG1309	transcriptional regulator
CP967_RS32975	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP967_RS32985	COG0009	L-threonylcarbamoyladenylate synthase
CP967_RS33005	COG1174	glycine betaine transport
CP967_RS33010	COG1174	glycine betaine transport
CP967_RS33025	COG0673	inositol 2-dehydrogenase activity
CP967_RS33030	COG3458	cephalosporin-C deacetylase activity
CP967_RS33045	COG0714	Associated with various cellular activities
CP967_RS33060	COG0656	L-ascorbic acid biosynthetic process
CP967_RS33090	COG1960	acyl-CoA dehydrogenase activity
CP967_RS33095	COG1960	acyl-CoA dehydrogenase activity
CP967_RS33140	COG0546	phosphoglycolate phosphatase activity
CP967_RS33145	COG1028	Short-chain dehydrogenase reductase Sdr
CP967_RS33155	COG2890	protein-(glutamine-N5) methyltransferase activity
CP967_RS33245	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CP967_RS33250	COG3239	Fatty acid desaturase
CP967_RS33280	COG2018	Roadblock/LC7 domain
CP967_RS33285	COG1024	Enoyl-CoA hydratase
CP967_RS33290	COG1070	Carbohydrate kinase
CP967_RS33295	COG3347	Dehydrogenase
CP967_RS33295	COG1028	Short-chain dehydrogenase reductase Sdr
CP967_RS33300	COG4952	isomerase
CP967_RS33315	COG1357	PFAM Pentapeptide repeats (8 copies)
CP967_RS33325	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CP967_RS33345	COG2340	Cysteine-rich secretory protein family
CP967_RS33355	COG0277	FAD linked oxidase domain protein
CP967_RS33365	COG2208	phosphoserine phosphatase activity
CP967_RS33370	COG1846	Transcriptional regulator
CP967_RS33375	COG1764	response to oxidative stress
CP967_RS33400	COG0181	hydroxymethylbilane synthase activity
CP967_RS33415	COG1295	ribonuclease BN
CP967_RS33420	COG1120	ATPase activity
CP967_RS33425	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CP967_RS33455	COG2197	response regulator
CP967_RS33575	COG0789	Transcriptional regulator
CP967_RS33600	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CP967_RS33605	COG3973	AAA domain
CP967_RS33630	COG1063	alcohol dehydrogenase
CP967_RS33635	COG0539	negative regulation of cytoplasmic translation
CP967_RS33660	COG2124	cytochrome p450
CP967_RS33665	COG1937	Protein conserved in bacteria
CP967_RS33670	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CP967_RS33680	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CP967_RS33680	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS