locus-tag	class	description
FYC74_RS00035	COG1234	tRNA 3'-trailer cleavage
FYC74_RS00060	COG1028	Short-chain dehydrogenase reductase Sdr
FYC74_RS00085	COG1028	Short-chain dehydrogenase reductase Sdr
FYC74_RS00100	COG2124	cytochrome p450
FYC74_RS00125	COG0604	alcohol dehydrogenase
FYC74_RS00125	COG3321	synthase
FYC74_RS00140	COG1902	pentaerythritol trinitrate reductase activity
FYC74_RS00145	COG0640	Transcriptional regulator
FYC74_RS00155	COG0667	Aldo Keto reductase
FYC74_RS00165	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FYC74_RS00175	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FYC74_RS00190	COG1472	Belongs to the glycosyl hydrolase 3 family
FYC74_RS00210	COG1902	pentaerythritol trinitrate reductase activity
FYC74_RS00220	COG2815	serine threonine protein kinase
FYC74_RS00220	COG0515	serine threonine protein kinase
FYC74_RS00280	COG3964	amidohydrolase
FYC74_RS00290	COG1309	transcriptional regulator
FYC74_RS00295	COG2409	Drug exporters of the RND superfamily
FYC74_RS00300	COG2132	Multicopper oxidase
FYC74_RS00320	COG1609	Transcriptional regulator
FYC74_RS00345	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FYC74_RS00350	COG0583	DNA-binding transcription factor activity
FYC74_RS00355	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FYC74_RS00360	COG1609	Transcriptional regulator
FYC74_RS00375	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FYC74_RS00380	COG1028	Short-chain dehydrogenase reductase Sdr
FYC74_RS00390	COG0477	Major facilitator Superfamily
FYC74_RS00410	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FYC74_RS00420	COG1012	belongs to the aldehyde dehydrogenase family
FYC74_RS00425	COG1891	lyase activity
FYC74_RS00445	COG1175	transmembrane transport
FYC74_RS00450	COG0395	ABC-type sugar transport system, permease component
FYC74_RS00460	COG3345	alpha-galactosidase
FYC74_RS00465	COG1940	carbohydrate kinase activity
FYC74_RS00490	COG2205	protein histidine kinase activity
FYC74_RS00495	COG0745	RESPONSE REGULATOR receiver
FYC74_RS00500	COG0577	efflux transmembrane transporter activity
FYC74_RS00510	COG1136	(ABC) transporter
FYC74_RS00520	COG0604	alcohol dehydrogenase
FYC74_RS00525	COG0460	homoserine dehydrogenase
FYC74_RS00535	COG0395	ABC-type sugar transport system, permease component
FYC74_RS00540	COG1175	transmembrane transport
FYC74_RS00565	COG1609	Transcriptional regulator
FYC74_RS00585	COG2208	phosphoserine phosphatase activity
FYC74_RS00585	COG2770	Histidine kinase
FYC74_RS00600	COG0667	Aldo Keto reductase
FYC74_RS00620	COG0477	Major facilitator Superfamily
FYC74_RS00630	COG0028	Belongs to the TPP enzyme family
FYC74_RS00635	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYC74_RS00640	COG2188	Transcriptional regulator
FYC74_RS00650	COG1263	PTS System
FYC74_RS00650	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FYC74_RS00655	COG1263	PTS System
FYC74_RS00655	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FYC74_RS00660	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FYC74_RS00670	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
FYC74_RS00685	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FYC74_RS00695	COG1984	allophanate hydrolase subunit 2
FYC74_RS00725	COG0402	S-adenosylhomocysteine deaminase activity
FYC74_RS00735	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYC74_RS00770	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FYC74_RS00780	COG1175	transmembrane transport
FYC74_RS00785	COG0395	ABC-type sugar transport system, permease component
FYC74_RS00790	COG1609	Transcriptional regulator
FYC74_RS00835	COG0747	negative chemotaxis
FYC74_RS00840	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FYC74_RS00845	COG0601	transmembrane transport
FYC74_RS00850	COG4172	Belongs to the ABC transporter superfamily
FYC74_RS00880	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FYC74_RS00885	COG1120	ATPase activity
FYC74_RS00890	COG0346	lactoylglutathione lyase activity
FYC74_RS00895	COG0659	secondary active sulfate transmembrane transporter activity
FYC74_RS00905	COG0789	Transcriptional regulator
FYC74_RS00955	COG2382	esterase
FYC74_RS00970	COG1132	(ABC) transporter
FYC74_RS00975	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FYC74_RS00980	COG1120	ATPase activity
FYC74_RS00985	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FYC74_RS00990	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FYC74_RS00995	COG3486	L-lysine 6-monooxygenase (NADPH) activity
FYC74_RS01025	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FYC74_RS01035	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FYC74_RS01070	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FYC74_RS01070	COG1017	nitric oxide dioxygenase activity
FYC74_RS01085	COG1140	nitrate reductase beta subunit
FYC74_RS01095	COG2181	nitrate reductase activity
FYC74_RS01100	COG4221	oxidoreductase activity
FYC74_RS01120	COG4221	oxidoreductase activity
FYC74_RS01125	COG3386	PFAM SMP-30 Gluconolaconase
FYC74_RS01140	COG1278	Cold shock
FYC74_RS01180	COG0395	ABC-type sugar transport system, permease component
FYC74_RS01185	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FYC74_RS01195	COG2208	phosphoserine phosphatase activity
FYC74_RS01200	COG0739	heme binding
FYC74_RS01200	COG0741	lytic transglycosylase activity
FYC74_RS01200	COG1196	nuclear chromosome segregation
FYC74_RS01215	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FYC74_RS01220	COG2340	Cysteine-rich secretory protein family
FYC74_RS01225	COG2205	protein histidine kinase activity
FYC74_RS01230	COG0745	RESPONSE REGULATOR receiver
FYC74_RS01250	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FYC74_RS01280	COG0142	geranyltranstransferase activity
FYC74_RS01285	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FYC74_RS01290	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FYC74_RS01295	COG2084	Dehydrogenase
FYC74_RS01300	COG1082	Xylose isomerase domain protein TIM barrel
FYC74_RS01305	COG0149	triose-phosphate isomerase activity
FYC74_RS01310	COG0698	ribose 5-phosphate isomerase
FYC74_RS01315	COG2376	Dihydroxyacetone kinase
FYC74_RS01325	COG2186	Transcriptional regulator
FYC74_RS01335	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FYC74_RS01345	COG2124	cytochrome p450
FYC74_RS01350	COG2124	cytochrome p450
FYC74_RS01365	COG2018	Roadblock/LC7 domain
FYC74_RS01385	COG2226	methyltransferase
FYC74_RS01390	COG0655	NAD(P)H dehydrogenase (quinone) activity
FYC74_RS01395	COG0783	Belongs to the Dps family
FYC74_RS01405	COG1191	sigma factor activity
FYC74_RS01410	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FYC74_RS01420	COG0505	Belongs to the CarA family
FYC74_RS01475	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
FYC74_RS01525	COG1595	DNA-templated transcription, initiation
FYC74_RS01540	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FYC74_RS01545	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FYC74_RS01565	COG0488	(ABC) transporter
FYC74_RS01575	COG1120	ATPase activity
FYC74_RS01580	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FYC74_RS01620	COG1028	Short-chain dehydrogenase reductase Sdr
FYC74_RS01625	COG2264	protein methyltransferase activity
FYC74_RS01690	COG1175	transmembrane transport
FYC74_RS01725	COG0277	FAD linked oxidase domain protein
FYC74_RS01760	COG3290	protein histidine kinase activity
FYC74_RS01780	COG0477	Major facilitator Superfamily
FYC74_RS01820	COG2080	2 iron, 2 sulfur cluster binding
FYC74_RS01825	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FYC74_RS01830	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FYC74_RS01870	COG1132	(ABC) transporter
FYC74_RS01925	COG2508	Transcriptional regulator
FYC74_RS01940	COG0673	inositol 2-dehydrogenase activity
FYC74_RS02035	COG1028	Short-chain dehydrogenase reductase Sdr
FYC74_RS02045	COG1028	Short-chain dehydrogenase reductase Sdr
FYC74_RS02060	COG1132	(ABC) transporter
FYC74_RS02115	COG0248	Ppx GppA phosphatase
FYC74_RS02130	COG2890	protein-(glutamine-N5) methyltransferase activity
FYC74_RS02145	COG1304	FMN binding
FYC74_RS02165	COG0667	Aldo Keto reductase
FYC74_RS02180	COG2124	cytochrome p450
FYC74_RS02195	COG0435	Glutathione S-transferase
FYC74_RS02210	COG2124	cytochrome p450
FYC74_RS02270	COG1796	DNA polymerase
FYC74_RS02270	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FYC74_RS02315	COG2706	6-phosphogluconolactonase activity
FYC74_RS02325	COG1309	transcriptional regulator
FYC74_RS02330	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FYC74_RS02330	COG2124	cytochrome p450
FYC74_RS02335	COG1357	PFAM Pentapeptide repeats (8 copies)
FYC74_RS02350	COG1609	Transcriptional regulator
FYC74_RS02365	COG1172	Belongs to the binding-protein-dependent transport system permease family
FYC74_RS02370	COG1172	Belongs to the binding-protein-dependent transport system permease family
FYC74_RS02375	COG1129	ABC transporter
FYC74_RS02385	COG3347	Dehydrogenase
FYC74_RS02385	COG1028	Short-chain dehydrogenase reductase Sdr
FYC74_RS02395	COG0247	lactate metabolic process
FYC74_RS02400	COG1139	Iron-sulfur cluster binding protein
FYC74_RS02405	COG1556	Lactate utilization protein
FYC74_RS02425	COG3540	Alkaline phosphatase
FYC74_RS02480	COG2409	Drug exporters of the RND superfamily
FYC74_RS02485	COG1846	Transcriptional regulator
FYC74_RS02490	COG0702	epimerase
FYC74_RS02540	COG0800	Aldolase
FYC74_RS02545	COG4948	Mandelate Racemase Muconate Lactonizing
FYC74_RS02550	COG2186	Transcriptional regulator
FYC74_RS02570	COG1082	Xylose isomerase domain protein TIM barrel
FYC74_RS02600	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FYC74_RS02655	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FYC74_RS02670	COG4310	Domain of unknown function (DUF2172)
FYC74_RS02680	COG1216	Glycosyl transferase, family 2
FYC74_RS02695	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FYC74_RS02705	COG3226	Transcriptional regulator
FYC74_RS02710	COG0738	Major facilitator superfamily
FYC74_RS02720	COG0494	nUDIX hydrolase
FYC74_RS02730	COG1132	(ABC) transporter
FYC74_RS02740	COG3246	L-lysine catabolic process to acetate
FYC74_RS02745	COG1250	3-hydroxyacyl-CoA dehydrogenase
FYC74_RS02765	COG1695	Transcriptional regulator
FYC74_RS02790	COG1309	transcriptional regulator
FYC74_RS02805	COG1073	alpha beta
FYC74_RS02820	COG1131	(ABC) transporter
FYC74_RS02825	COG1725	Transcriptional regulator
FYC74_RS02830	COG1802	Transcriptional regulator
FYC74_RS02835	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FYC74_RS02845	COG1012	belongs to the aldehyde dehydrogenase family
FYC74_RS02885	COG1028	Short-chain dehydrogenase reductase Sdr
FYC74_RS02900	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FYC74_RS02905	COG4569	acetaldehyde dehydrogenase (acetylating) activity
FYC74_RS02910	COG1028	Short-chain dehydrogenase reductase Sdr
FYC74_RS02915	COG0129	dihydroxy-acid dehydratase activity
FYC74_RS02920	COG1414	Transcriptional regulator
FYC74_RS02925	COG0473	3-isopropylmalate dehydrogenase activity
FYC74_RS02935	COG3622	Belongs to the hyi family
FYC74_RS02955	COG0659	secondary active sulfate transmembrane transporter activity
FYC74_RS03015	COG0242	peptide deformylase activity
FYC74_RS03025	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FYC74_RS03030	COG1609	Transcriptional regulator
FYC74_RS03045	COG0583	DNA-binding transcription factor activity
FYC74_RS03055	COG4221	oxidoreductase activity
FYC74_RS03075	COG1053	succinate dehydrogenase
FYC74_RS03075	COG3976	FMN-binding domain protein
FYC74_RS03090	COG3629	intracellular signal transduction
FYC74_RS03090	COG3903	Transcriptional regulator
FYC74_RS03095	COG0596	Alpha beta hydrolase
FYC74_RS03120	COG3467	pyridoxamine 5'-phosphate
FYC74_RS03125	COG2084	Dehydrogenase
FYC74_RS03145	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FYC74_RS03150	COG0121	glutamine amidotransferase
FYC74_RS03155	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
FYC74_RS03165	COG3360	Dodecin
FYC74_RS03175	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FYC74_RS03200	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FYC74_RS03205	COG1053	succinate dehydrogenase
FYC74_RS03215	COG0583	DNA-binding transcription factor activity
FYC74_RS03225	COG0583	DNA-binding transcription factor activity
FYC74_RS03270	COG0726	polysaccharide deacetylase
FYC74_RS03280	COG0531	amino acid
FYC74_RS03295	COG2843	Capsule synthesis protein
FYC74_RS03315	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FYC74_RS03340	COG0395	ABC-type sugar transport system, permease component
FYC74_RS03345	COG1175	transmembrane transport
FYC74_RS03355	COG1609	Transcriptional regulator
FYC74_RS03390	COG3537	Alpha-1,2-mannosidase
FYC74_RS03395	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FYC74_RS03400	COG0297	glycogen (starch) synthase activity
FYC74_RS03420	COG1028	Short-chain dehydrogenase reductase Sdr
FYC74_RS03425	COG1309	transcriptional regulator
FYC74_RS03430	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FYC74_RS03440	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FYC74_RS03510	COG2124	cytochrome p450
FYC74_RS03525	COG1132	(ABC) transporter
FYC74_RS03535	COG0174	glutamine synthetase
FYC74_RS03550	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FYC74_RS03555	COG1802	Transcriptional regulator
FYC74_RS03560	COG1017	nitric oxide dioxygenase activity
FYC74_RS03560	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FYC74_RS03565	COG2423	ornithine cyclodeaminase activity
FYC74_RS03570	COG2031	fatty acid transporter
FYC74_RS03590	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FYC74_RS03595	COG0477	Major facilitator Superfamily
FYC74_RS03600	COG2376	Dihydroxyacetone kinase
FYC74_RS03605	COG2376	Dihydroxyacetone kinase
FYC74_RS03640	COG1653	transport
FYC74_RS03645	COG1175	transmembrane transport
FYC74_RS03650	COG0395	ABC-type sugar transport system, permease component
FYC74_RS03655	COG0366	Alpha amylase catalytic
FYC74_RS03660	COG1132	(ABC) transporter
FYC74_RS03680	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FYC74_RS03695	COG0668	transmembrane transport
FYC74_RS03700	COG2838	Isocitrate dehydrogenase
FYC74_RS03710	COG2124	cytochrome p450
FYC74_RS03725	COG1404	Belongs to the peptidase S8 family
FYC74_RS03735	COG2197	response regulator
FYC74_RS03745	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FYC74_RS03750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FYC74_RS03755	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FYC74_RS03780	COG0778	Nitroreductase
FYC74_RS03820	COG2162	N-hydroxyarylamine O-acetyltransferase activity
FYC74_RS03830	COG3321	synthase
FYC74_RS03830	COG0604	alcohol dehydrogenase
FYC74_RS03860	COG0318	PFAM AMP-dependent synthetase and ligase
FYC74_RS03870	COG0546	phosphoglycolate phosphatase activity
FYC74_RS03885	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FYC74_RS03930	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FYC74_RS03960	COG1960	acyl-CoA dehydrogenase activity
FYC74_RS04005	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FYC74_RS04155	COG0656	L-ascorbic acid biosynthetic process
FYC74_RS04165	COG0693	protein deglycase activity
FYC74_RS04200	COG0542	response to heat
FYC74_RS04215	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FYC74_RS04220	COG0443	Heat shock 70 kDa protein
FYC74_RS04225	COG3835	regulator
FYC74_RS04290	COG0438	transferase activity, transferring glycosyl groups
FYC74_RS04295	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FYC74_RS04375	COG3547	Transposase (IS116 IS110 IS902 family)
FYC74_RS04435	COG1181	Belongs to the D-alanine--D-alanine ligase family
FYC74_RS04595	COG0714	Associated with various cellular activities
FYC74_RS04610	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FYC74_RS04615	COG0798	PFAM Bile acid sodium symporter
FYC74_RS04620	COG0640	Transcriptional regulator
FYC74_RS04625	COG2226	methyltransferase
FYC74_RS04655	COG3344	reverse transcriptase
FYC74_RS04770	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FYC74_RS04775	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FYC74_RS04795	COG0010	Belongs to the arginase family
FYC74_RS04815	COG0339	signal peptide processing
FYC74_RS04830	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FYC74_RS04835	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FYC74_RS04840	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FYC74_RS04845	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FYC74_RS04850	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FYC74_RS04885	COG0385	Bile acid
FYC74_RS04890	COG2814	Major facilitator Superfamily
FYC74_RS04905	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FYC74_RS04910	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FYC74_RS04915	COG2186	Transcriptional regulator
FYC74_RS04920	COG0673	inositol 2-dehydrogenase activity
FYC74_RS04925	COG0673	inositol 2-dehydrogenase activity
FYC74_RS04955	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FYC74_RS04965	COG3718	enzyme involved in inositol metabolism
FYC74_RS04970	COG3962	Belongs to the TPP enzyme family
FYC74_RS04975	COG2188	Transcriptional regulator
FYC74_RS04995	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FYC74_RS05010	COG1120	ATPase activity
FYC74_RS05015	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FYC74_RS05020	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FYC74_RS05030	COG2375	cellular response to nickel ion
FYC74_RS05035	COG1535	isochorismatase
FYC74_RS05035	COG3433	isochorismatase activity
FYC74_RS05040	COG1169	isochorismate synthase
FYC74_RS05050	COG3486	L-lysine 6-monooxygenase (NADPH) activity
FYC74_RS05055	COG1535	isochorismatase
FYC74_RS05055	COG3433	isochorismatase activity
FYC74_RS05065	COG1028	Short-chain dehydrogenase reductase Sdr
FYC74_RS05085	COG0475	glutathione-regulated potassium exporter activity
FYC74_RS05105	COG2986	histidine ammonia-lyase
FYC74_RS05110	COG2205	protein histidine kinase activity
FYC74_RS05115	COG0745	RESPONSE REGULATOR receiver
FYC74_RS05140	COG0318	PFAM AMP-dependent synthetase and ligase
FYC74_RS05145	COG0183	Belongs to the thiolase family
FYC74_RS05150	COG2267	carboxylic ester hydrolase activity
FYC74_RS05185	COG1320	monovalent cation:proton antiporter activity
FYC74_RS05200	COG0651	ATP synthesis coupled electron transport
FYC74_RS05205	COG1006	Multisubunit Na H antiporter MnhC subunit
FYC74_RS05210	COG2111	Na H antiporter
FYC74_RS05210	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FYC74_RS05240	COG0583	DNA-binding transcription factor activity
FYC74_RS05245	COG0156	8-amino-7-oxononanoate synthase activity
FYC74_RS05250	COG1063	alcohol dehydrogenase
FYC74_RS05295	COG1022	Amp-dependent synthetase and ligase
FYC74_RS05305	COG1960	acyl-CoA dehydrogenase activity
FYC74_RS05310	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYC74_RS05315	COG1309	transcriptional regulator
FYC74_RS05330	COG1309	transcriptional regulator
FYC74_RS05345	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FYC74_RS05350	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FYC74_RS05360	COG1169	isochorismate synthase
FYC74_RS05365	COG1132	(ABC) transporter
FYC74_RS05370	COG1132	(ABC) transporter
FYC74_RS05370	COG2375	cellular response to nickel ion
FYC74_RS05405	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
FYC74_RS05405	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FYC74_RS05410	COG1021	2,3-dihydroxybenzoate-AMP ligase
FYC74_RS05425	COG0601	transmembrane transport
FYC74_RS05445	COG1408	metallophosphoesterase
FYC74_RS05485	COG2365	Tyrosine phosphatase family
FYC74_RS05505	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FYC74_RS05510	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FYC74_RS05525	COG1657	PFAM Prenyltransferase squalene oxidase
FYC74_RS05535	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
FYC74_RS05545	COG1562	ergosterol biosynthetic process
FYC74_RS05550	COG1134	teichoic acid transport
FYC74_RS05590	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FYC74_RS05600	COG1024	Enoyl-CoA hydratase
FYC74_RS05620	COG2183	response to ionizing radiation
FYC74_RS05625	COG0488	(ABC) transporter
FYC74_RS05635	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FYC74_RS05655	COG1113	amino acid transport
FYC74_RS05660	COG0789	Transcriptional regulator
FYC74_RS05665	COG1024	Enoyl-CoA hydratase
FYC74_RS05665	COG1250	3-hydroxyacyl-CoA dehydrogenase
FYC74_RS05670	COG0183	Belongs to the thiolase family
FYC74_RS05675	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYC74_RS05680	COG3268	Saccharopine dehydrogenase
FYC74_RS05695	COG1515	deoxyribonuclease V activity
FYC74_RS05715	COG0488	(ABC) transporter
FYC74_RS05720	COG1834	amidinotransferase
FYC74_RS05740	COG0656	L-ascorbic acid biosynthetic process
FYC74_RS05770	COG1793	dna ligase
FYC74_RS05780	COG1470	cell adhesion involved in biofilm formation
FYC74_RS05790	COG3485	protocatechuate 3,4-dioxygenase
FYC74_RS05795	COG3485	protocatechuate 3,4-dioxygenase
FYC74_RS05800	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FYC74_RS05805	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FYC74_RS05835	COG3511	phospholipase C
FYC74_RS05840	COG0667	Aldo Keto reductase
FYC74_RS05865	COG3938	Belongs to the proline racemase family
FYC74_RS05885	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FYC74_RS05910	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FYC74_RS05920	COG1486	melibiose metabolic process
FYC74_RS05940	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FYC74_RS05955	COG0166	Belongs to the GPI family
FYC74_RS05960	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FYC74_RS05970	COG3185	4-Hydroxyphenylpyruvate dioxygenase
FYC74_RS05970	COG1082	Xylose isomerase domain protein TIM barrel
FYC74_RS05975	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FYC74_RS05985	COG0477	Major facilitator Superfamily
FYC74_RS05995	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FYC74_RS06015	COG0297	glycogen (starch) synthase activity
FYC74_RS06040	COG0300	oxidoreductase activity
FYC74_RS06045	COG1028	Short-chain dehydrogenase reductase Sdr
FYC74_RS06050	COG1309	transcriptional regulator
FYC74_RS06060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FYC74_RS06095	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FYC74_RS06115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FYC74_RS06120	COG0765	amino acid transport
FYC74_RS06135	COG0300	oxidoreductase activity
FYC74_RS06140	COG0446	pyridine nucleotide-disulphide oxidoreductase
FYC74_RS06140	COG1902	pentaerythritol trinitrate reductase activity
FYC74_RS06160	COG1733	regulation of RNA biosynthetic process
FYC74_RS06165	COG0596	Alpha beta hydrolase
FYC74_RS06185	COG2723	6-phospho-beta-galactosidase activity
FYC74_RS06190	COG0395	ABC-type sugar transport system, permease component
FYC74_RS06195	COG1175	transmembrane transport
FYC74_RS06200	COG2182	Extracellular solute-binding protein
FYC74_RS06235	COG1012	belongs to the aldehyde dehydrogenase family
FYC74_RS06245	COG0045	succinate-CoA ligase (ADP-forming) activity
FYC74_RS06255	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYC74_RS06265	COG2223	nitrite transmembrane transporter activity
FYC74_RS06300	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FYC74_RS06320	COG0673	inositol 2-dehydrogenase activity
FYC74_RS06330	COG1172	Belongs to the binding-protein-dependent transport system permease family
FYC74_RS06335	COG1129	ABC transporter
FYC74_RS06350	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FYC74_RS06365	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FYC74_RS06370	COG3383	formate dehydrogenase (NAD+) activity
FYC74_RS06375	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FYC74_RS06385	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FYC74_RS06410	COG0656	L-ascorbic acid biosynthetic process
FYC74_RS06415	COG2226	methyltransferase
FYC74_RS06420	COG5297	Belongs to the glycosyl hydrolase family 6
FYC74_RS06425	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FYC74_RS06425	COG4106	trans-aconitate 2-methyltransferase activity
FYC74_RS06430	COG2154	pterin-4-alpha-carbinolamine dehydratase
FYC74_RS06500	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FYC74_RS06530	COG1597	lipid kinase activity
FYC74_RS06535	COG2226	methyltransferase
FYC74_RS06590	COG3285	dna ligase
FYC74_RS06590	COG1793	dna ligase
FYC74_RS06605	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FYC74_RS06630	COG1619	proteins homologs of microcin C7 resistance protein MccF
FYC74_RS06635	COG0823	Involved in the tonB-independent uptake of proteins
FYC74_RS06635	COG1506	peptidase
FYC74_RS06635	COG4946	Tricorn protease homolog
FYC74_RS06640	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FYC74_RS06645	COG2362	D-Aminopeptidase
FYC74_RS06650	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FYC74_RS06660	COG2208	phosphoserine phosphatase activity
FYC74_RS06660	COG2172	sigma factor antagonist activity
FYC74_RS06660	COG1366	Belongs to the anti-sigma-factor antagonist family
FYC74_RS06710	COG0604	alcohol dehydrogenase
FYC74_RS06715	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FYC74_RS06715	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FYC74_RS06720	COG2301	Belongs to the HpcH HpaI aldolase family
FYC74_RS06730	COG1960	acyl-CoA dehydrogenase activity
FYC74_RS06735	COG0688	phosphatidylethanolamine metabolic process
FYC74_RS06745	COG1929	Belongs to the glycerate kinase type-1 family
FYC74_RS06755	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FYC74_RS06770	COG0640	Transcriptional regulator
FYC74_RS06780	COG3540	Alkaline phosphatase
FYC74_RS06790	COG2610	gluconate transmembrane transporter activity
FYC74_RS06795	COG0583	DNA-binding transcription factor activity
FYC74_RS06805	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FYC74_RS06815	COG0477	Major facilitator Superfamily
FYC74_RS06845	COG3835	regulator
FYC74_RS06860	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYC74_RS06865	COG1024	Enoyl-CoA hydratase
FYC74_RS06875	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FYC74_RS06880	COG3958	Transketolase
FYC74_RS06885	COG3959	Transketolase, thiamine diphosphate binding domain
FYC74_RS06890	COG1082	Xylose isomerase domain protein TIM barrel
FYC74_RS06900	COG1802	Transcriptional regulator
FYC74_RS06910	COG0439	Biotin carboxylase
FYC74_RS06940	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
FYC74_RS06950	COG0483	inositol monophosphate 1-phosphatase activity
FYC74_RS06965	COG4221	oxidoreductase activity
FYC74_RS06995	COG3629	intracellular signal transduction
FYC74_RS06995	COG3903	Transcriptional regulator
FYC74_RS07000	COG3844	kynureninase activity
FYC74_RS07015	COG0475	glutathione-regulated potassium exporter activity
FYC74_RS07025	COG3629	intracellular signal transduction
FYC74_RS07025	COG3903	Transcriptional regulator
FYC74_RS07035	COG0477	Major facilitator Superfamily
FYC74_RS07045	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FYC74_RS07050	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FYC74_RS07075	COG1228	amidohydrolase
FYC74_RS07080	COG3483	tryptophan 2,3-dioxygenase activity
FYC74_RS07090	COG1169	isochorismate synthase
FYC74_RS07100	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FYC74_RS07105	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FYC74_RS07115	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FYC74_RS07135	COG0405	Gamma-glutamyltransferase
FYC74_RS07145	COG0673	inositol 2-dehydrogenase activity
FYC74_RS07165	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FYC74_RS07175	COG0512	Glutamine amidotransferase of anthranilate synthase
FYC74_RS07175	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FYC74_RS07190	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FYC74_RS07200	COG2124	cytochrome p450
FYC74_RS07210	COG2226	methyltransferase
FYC74_RS07230	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FYC74_RS07240	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FYC74_RS07255	COG0583	DNA-binding transcription factor activity
FYC74_RS07265	COG0667	Aldo Keto reductase
FYC74_RS07290	COG2409	Drug exporters of the RND superfamily
FYC74_RS07295	COG4221	oxidoreductase activity
FYC74_RS07315	COG0596	Alpha beta hydrolase
FYC74_RS07320	COG1120	ATPase activity
FYC74_RS07325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FYC74_RS07335	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FYC74_RS07340	COG3433	isochorismatase activity
FYC74_RS07340	COG1535	isochorismatase
FYC74_RS07415	COG0523	cobalamin synthesis protein
FYC74_RS07435	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FYC74_RS07440	COG1121	(ABC) transporter
FYC74_RS07450	COG0803	Belongs to the bacterial solute-binding protein 9 family
FYC74_RS07485	COG0444	Belongs to the ABC transporter superfamily
FYC74_RS07525	COG2197	response regulator
FYC74_RS07535	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FYC74_RS07545	COG1940	carbohydrate kinase activity
FYC74_RS07565	COG2188	Transcriptional regulator
FYC74_RS07575	COG1335	isochorismatase
FYC74_RS07590	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FYC74_RS07605	COG2066	Belongs to the glutaminase family
FYC74_RS07610	COG4266	Belongs to the allantoicase family
FYC74_RS07615	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FYC74_RS07620	COG1414	Transcriptional regulator
FYC74_RS07635	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FYC74_RS07645	COG3046	protein related to deoxyribodipyrimidine photolyase
FYC74_RS07655	COG1285	pathogenesis
FYC74_RS07680	COG4264	IucA IucC family
FYC74_RS07700	COG0436	Aminotransferase
FYC74_RS07705	COG0406	alpha-ribazole phosphatase activity
FYC74_RS07715	COG2233	PERMEase
FYC74_RS07730	COG2351	hydroxyisourate hydrolase activity
FYC74_RS07750	COG3622	Belongs to the hyi family
FYC74_RS07755	COG2084	Dehydrogenase
FYC74_RS07760	COG0753	catalase activity
FYC74_RS07770	COG3960	tartronate-semialdehyde synthase activity
FYC74_RS07805	COG0318	PFAM AMP-dependent synthetase and ligase
FYC74_RS07810	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FYC74_RS07815	COG2197	response regulator
FYC74_RS07830	COG1295	ribonuclease BN
FYC74_RS07870	COG2319	Wd-40 repeat
FYC74_RS07870	COG4249	Peptidase C14 caspase catalytic subunit p20
FYC74_RS07905	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FYC74_RS07905	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FYC74_RS07920	COG0438	transferase activity, transferring glycosyl groups
FYC74_RS07925	COG0859	PFAM glycosyl transferase family 9
FYC74_RS07930	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FYC74_RS07940	COG2192	nodulation
FYC74_RS07970	COG2252	PERMEase
FYC74_RS07975	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FYC74_RS07990	COG3835	regulator
FYC74_RS08025	COG2197	response regulator
FYC74_RS08035	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FYC74_RS08040	COG1802	Transcriptional regulator
FYC74_RS08065	COG0028	Belongs to the TPP enzyme family
FYC74_RS08075	COG2080	2 iron, 2 sulfur cluster binding
FYC74_RS08080	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FYC74_RS08080	COG2010	Cytochrome c
FYC74_RS08105	COG0183	Belongs to the thiolase family
FYC74_RS08120	COG1960	acyl-CoA dehydrogenase activity
FYC74_RS08140	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FYC74_RS08145	COG1162	GTPase activity
FYC74_RS08160	COG0277	FAD linked oxidase domain protein
FYC74_RS08170	COG2197	response regulator
FYC74_RS08185	COG2040	homocysteine
FYC74_RS08200	COG0714	Associated with various cellular activities
FYC74_RS08215	COG2027	D-alanyl-D-alanine carboxypeptidase
FYC74_RS08265	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FYC74_RS08280	COG1518	maintenance of DNA repeat elements
FYC74_RS08295	COG1857	crispr-associated protein
FYC74_RS08360	COG1940	carbohydrate kinase activity
FYC74_RS08360	COG1846	Transcriptional regulator
FYC74_RS08385	COG1846	Transcriptional regulator
FYC74_RS08385	COG1940	carbohydrate kinase activity
FYC74_RS08395	COG1960	acyl-CoA dehydrogenase activity
FYC74_RS08425	COG0175	sulfate reduction
FYC74_RS08430	COG0529	Catalyzes the synthesis of activated sulfate
FYC74_RS08455	COG1116	anion transmembrane transporter activity
FYC74_RS08460	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FYC74_RS08480	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FYC74_RS08495	COG1175	transmembrane transport
FYC74_RS08540	COG3173	Aminoglycoside phosphotransferase
FYC74_RS08565	COG1309	transcriptional regulator
FYC74_RS08610	COG1732	Glycine betaine
FYC74_RS08615	COG1174	glycine betaine transport
FYC74_RS08620	COG1174	glycine betaine transport
FYC74_RS08645	COG0745	RESPONSE REGULATOR receiver
FYC74_RS08650	COG2205	protein histidine kinase activity
FYC74_RS08655	COG3629	intracellular signal transduction
FYC74_RS08655	COG3903	Transcriptional regulator
FYC74_RS08670	COG3629	intracellular signal transduction
FYC74_RS08670	COG3903	Transcriptional regulator
FYC74_RS08690	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FYC74_RS08695	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FYC74_RS08735	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FYC74_RS08735	COG0723	plastoquinol--plastocyanin reductase activity
FYC74_RS08740	COG0726	polysaccharide deacetylase
FYC74_RS08745	COG1733	regulation of RNA biosynthetic process
FYC74_RS08750	COG0604	alcohol dehydrogenase
FYC74_RS08750	COG3321	synthase
FYC74_RS08750	COG1028	Short-chain dehydrogenase reductase Sdr
FYC74_RS08770	COG4152	abc transporter atp-binding protein
FYC74_RS08780	COG3220	belongs to the UPF0276 family
FYC74_RS08795	COG3253	May function as heme-dependent peroxidase
FYC74_RS08800	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
FYC74_RS08805	COG0446	pyridine nucleotide-disulphide oxidoreductase
FYC74_RS08880	COG1472	Belongs to the glycosyl hydrolase 3 family
FYC74_RS08885	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FYC74_RS08905	COG0183	Belongs to the thiolase family
FYC74_RS08910	COG1024	Enoyl-CoA hydratase
FYC74_RS08910	COG1250	3-hydroxyacyl-CoA dehydrogenase
FYC74_RS08925	COG0531	amino acid
FYC74_RS08930	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FYC74_RS08935	COG4214	carbohydrate transport
FYC74_RS08945	COG4213	ABC transporter substrate-binding protein
FYC74_RS08950	COG1940	carbohydrate kinase activity
FYC74_RS08955	COG0395	ABC-type sugar transport system, permease component
FYC74_RS08960	COG1175	transmembrane transport
FYC74_RS08965	COG1653	transport
FYC74_RS08990	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FYC74_RS09000	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FYC74_RS09040	COG1233	COG1233 Phytoene dehydrogenase and related
FYC74_RS09045	COG2130	NADP-dependent
FYC74_RS09055	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FYC74_RS09060	COG1414	Transcriptional regulator
FYC74_RS09070	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FYC74_RS09075	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FYC74_RS09100	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FYC74_RS09110	COG2124	cytochrome p450
FYC74_RS09185	COG1902	pentaerythritol trinitrate reductase activity
FYC74_RS09190	COG1024	Enoyl-CoA hydratase
FYC74_RS09200	COG0531	amino acid
FYC74_RS09205	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FYC74_RS09210	COG2235	arginine
FYC74_RS09215	COG0475	glutathione-regulated potassium exporter activity
FYC74_RS09240	COG1799	cell septum assembly
FYC74_RS09245	COG0247	lactate metabolic process
FYC74_RS09245	COG0277	FAD linked oxidase domain protein
FYC74_RS09260	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FYC74_RS09265	COG0310	cobalt ion transport
FYC74_RS09270	COG1930	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
FYC74_RS09280	COG1122	ATPase activity
FYC74_RS09285	COG0477	Major facilitator Superfamily
FYC74_RS09300	COG2409	Drug exporters of the RND superfamily
FYC74_RS09305	COG4585	Histidine kinase
FYC74_RS09310	COG2197	response regulator
FYC74_RS09365	COG1063	alcohol dehydrogenase
FYC74_RS09380	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FYC74_RS09410	COG0395	ABC-type sugar transport system, permease component
FYC74_RS09415	COG1175	transmembrane transport
FYC74_RS09435	COG1609	Transcriptional regulator
FYC74_RS09455	COG2867	negative regulation of translational initiation
FYC74_RS09465	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FYC74_RS09470	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FYC74_RS09480	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FYC74_RS09485	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FYC74_RS09490	COG1126	abc transporter atp-binding protein
FYC74_RS09500	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FYC74_RS09535	COG1902	pentaerythritol trinitrate reductase activity
FYC74_RS09550	COG3629	intracellular signal transduction
FYC74_RS09555	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FYC74_RS09565	COG0477	Major facilitator Superfamily
FYC74_RS09570	COG0604	alcohol dehydrogenase
FYC74_RS09595	COG2851	Citrate transporter
FYC74_RS09615	COG0473	3-isopropylmalate dehydrogenase activity
FYC74_RS09630	COG2188	Transcriptional regulator
FYC74_RS09640	COG1175	transmembrane transport
FYC74_RS09645	COG0395	ABC-type sugar transport system, permease component
FYC74_RS09650	COG4948	Mandelate Racemase Muconate Lactonizing
FYC74_RS09690	COG3340	Belongs to the peptidase S51 family
FYC74_RS09695	COG0583	DNA-binding transcription factor activity
FYC74_RS09710	COG1132	(ABC) transporter
FYC74_RS09715	COG1132	(ABC) transporter
FYC74_RS09725	COG0515	serine threonine protein kinase
FYC74_RS09780	COG3654	unkown
FYC74_RS09790	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FYC74_RS09795	COG0531	amino acid
FYC74_RS09805	COG0569	domain protein
FYC74_RS09835	COG1136	(ABC) transporter
FYC74_RS09835	COG4591	ABC-type transport system involved in lipoprotein release permease component
FYC74_RS09845	COG0756	dUTP diphosphatase activity
FYC74_RS09870	COG2205	protein histidine kinase activity
FYC74_RS09875	COG0745	RESPONSE REGULATOR receiver
FYC74_RS09890	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FYC74_RS09925	COG1435	thymidine kinase activity
FYC74_RS09945	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FYC74_RS09950	COG1802	Transcriptional regulator
FYC74_RS09965	COG0612	Peptidase, M16
FYC74_RS09970	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FYC74_RS10010	COG0583	DNA-binding transcription factor activity
FYC74_RS10020	COG3290	protein histidine kinase activity
FYC74_RS10025	COG4565	transcriptional regulatory protein
FYC74_RS10030	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FYC74_RS10040	COG2197	response regulator
FYC74_RS10055	COG0187	DNA topoisomerase II activity
FYC74_RS10070	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FYC74_RS10075	COG2186	Transcriptional regulator
FYC74_RS10110	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FYC74_RS10130	COG0588	phosphoglycerate mutase activity
FYC74_RS10145	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FYC74_RS10150	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FYC74_RS10155	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FYC74_RS10190	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FYC74_RS10200	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FYC74_RS10205	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FYC74_RS10215	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FYC74_RS10235	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FYC74_RS10240	COG2197	response regulator
FYC74_RS10245	COG3851	Histidine kinase
FYC74_RS10270	COG2205	protein histidine kinase activity
FYC74_RS10275	COG0745	RESPONSE REGULATOR receiver
FYC74_RS10280	COG1126	abc transporter atp-binding protein
FYC74_RS10285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FYC74_RS10290	COG0765	amino acid transport
FYC74_RS10295	COG0765	amino acid transport
FYC74_RS10310	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FYC74_RS10320	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FYC74_RS10330	COG1063	alcohol dehydrogenase
FYC74_RS10335	COG0477	Major facilitator Superfamily
FYC74_RS10340	COG0246	Mannitol dehydrogenase
FYC74_RS10355	COG0628	permease
FYC74_RS10380	COG2207	Transcriptional regulator
FYC74_RS10380	COG1917	Cupin 2, conserved barrel domain protein
FYC74_RS10385	COG1201	RNA secondary structure unwinding
FYC74_RS10390	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FYC74_RS10400	COG1396	sequence-specific DNA binding
FYC74_RS10405	COG1058	Belongs to the CinA family
FYC74_RS10405	COG1546	Belongs to the CinA family
FYC74_RS10415	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FYC74_RS10425	COG1674	ftsk spoiiie
FYC74_RS10435	COG2205	protein histidine kinase activity
FYC74_RS10435	COG0784	Response regulator, receiver
FYC74_RS10440	COG2770	Histidine kinase
FYC74_RS10440	COG2208	phosphoserine phosphatase activity
FYC74_RS10470	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FYC74_RS10475	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FYC74_RS10480	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
FYC74_RS10500	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FYC74_RS10505	COG0612	Peptidase, M16
FYC74_RS10510	COG1185	polyribonucleotide nucleotidyltransferase activity
FYC74_RS10515	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FYC74_RS10525	COG0455	bacterial-type flagellum organization
FYC74_RS10530	COG0747	negative chemotaxis
FYC74_RS10535	COG0601	transmembrane transport
FYC74_RS10540	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FYC74_RS10550	COG4608	Belongs to the ABC transporter superfamily
FYC74_RS10565	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FYC74_RS10570	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FYC74_RS10595	COG0779	Required for maturation of 30S ribosomal subunits
FYC74_RS10615	COG0442	prolyl-tRNA aminoacylation
FYC74_RS10630	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FYC74_RS10635	COG0750	zinc metalloprotease
FYC74_RS10640	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FYC74_RS10660	COG1012	belongs to the aldehyde dehydrogenase family
FYC74_RS10665	COG2508	Transcriptional regulator
FYC74_RS10695	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FYC74_RS10700	COG1177	transmembrane transport
FYC74_RS10710	COG3842	ATPase activity
FYC74_RS10740	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FYC74_RS10745	COG0584	glycerophosphoryl diester phosphodiesterase
FYC74_RS10750	COG1012	belongs to the aldehyde dehydrogenase family
FYC74_RS10760	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FYC74_RS10790	COG3842	ATPase activity
FYC74_RS10795	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FYC74_RS10805	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FYC74_RS10810	COG0575	Belongs to the CDS family
FYC74_RS10815	COG0233	cytoplasmic translational termination
FYC74_RS10820	COG0528	UMP kinase activity
FYC74_RS10825	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FYC74_RS10830	COG0052	Belongs to the universal ribosomal protein uS2 family
FYC74_RS10845	COG1191	sigma factor activity
FYC74_RS10860	COG0792	nuclease activity
FYC74_RS10875	COG0681	Belongs to the peptidase S26 family
FYC74_RS10880	COG0681	Belongs to the peptidase S26 family
FYC74_RS10890	COG0681	Belongs to the peptidase S26 family
FYC74_RS10895	COG0335	large ribosomal subunit rRNA binding
FYC74_RS10900	COG0336	Belongs to the RNA methyltransferase TrmD family
FYC74_RS10905	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FYC74_RS10910	COG1837	Belongs to the UPF0109 family
FYC74_RS10915	COG0228	four-way junction DNA binding
FYC74_RS10940	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FYC74_RS10975	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FYC74_RS10985	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FYC74_RS10990	COG0318	PFAM AMP-dependent synthetase and ligase
FYC74_RS10995	COG0596	Alpha beta hydrolase
FYC74_RS11010	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FYC74_RS11020	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FYC74_RS11025	COG0477	Major facilitator Superfamily
FYC74_RS11040	COG1254	Belongs to the acylphosphatase family
FYC74_RS11045	COG2340	Cysteine-rich secretory protein family
FYC74_RS11050	COG1028	Short-chain dehydrogenase reductase Sdr
FYC74_RS11060	COG1733	regulation of RNA biosynthetic process
FYC74_RS11065	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FYC74_RS11070	COG0571	ribonuclease III activity
FYC74_RS11075	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FYC74_RS11090	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FYC74_RS11095	COG0742	ribosomal rna small subunit methyltransferase
FYC74_RS11105	COG1461	Dihydroxyacetone kinase
FYC74_RS11110	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FYC74_RS11115	COG0351	phosphomethylpyrimidine kinase
FYC74_RS11130	COG1181	Belongs to the D-alanine--D-alanine ligase family
FYC74_RS11135	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FYC74_RS11145	COG1920	GTP binding
FYC74_RS11155	COG0776	regulation of translation
FYC74_RS11165	COG0066	3-isopropylmalate dehydratase activity
FYC74_RS11170	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FYC74_RS11175	COG1414	Transcriptional regulator
FYC74_RS11210	COG1917	Cupin 2, conserved barrel domain protein
FYC74_RS11210	COG4977	sequence-specific DNA binding
FYC74_RS11220	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FYC74_RS11225	COG0179	Fumarylacetoacetate (FAA) hydrolase
FYC74_RS11235	COG5002	protein histidine kinase activity
FYC74_RS11240	COG2018	Roadblock/LC7 domain
FYC74_RS11260	COG2018	Roadblock/LC7 domain
FYC74_RS11280	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FYC74_RS11310	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FYC74_RS11315	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FYC74_RS11320	COG0473	3-isopropylmalate dehydrogenase activity
FYC74_RS11325	COG1012	belongs to the aldehyde dehydrogenase family
FYC74_RS11330	COG0506	proline dehydrogenase activity
FYC74_RS11345	COG0477	Major facilitator Superfamily
FYC74_RS11350	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FYC74_RS11355	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FYC74_RS11360	COG0440	acetolactate synthase activity
FYC74_RS11370	COG5001	Diguanylate cyclase
FYC74_RS11380	COG0667	Aldo Keto reductase
FYC74_RS11385	COG2133	pyrroloquinoline quinone binding
FYC74_RS11400	COG2197	response regulator
FYC74_RS11415	COG2409	Drug exporters of the RND superfamily
FYC74_RS11420	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FYC74_RS11430	COG0154	amidase activity
FYC74_RS11435	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FYC74_RS11445	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FYC74_RS11455	COG4221	oxidoreductase activity
FYC74_RS11460	COG1611	Belongs to the LOG family
FYC74_RS11470	COG0482	sulfurtransferase activity
FYC74_RS11495	COG1309	transcriptional regulator
FYC74_RS11505	COG0789	Transcriptional regulator
FYC74_RS11515	COG2860	membrane
FYC74_RS11520	COG4608	Belongs to the ABC transporter superfamily
FYC74_RS11525	COG0444	Belongs to the ABC transporter superfamily
FYC74_RS11535	COG4166	transmembrane transport
FYC74_RS11540	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FYC74_RS11560	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FYC74_RS11565	COG0509	glycine decarboxylation via glycine cleavage system
FYC74_RS11570	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FYC74_RS11575	COG1760	l-serine dehydratase
FYC74_RS11585	COG4585	Histidine kinase
FYC74_RS11590	COG2197	response regulator
FYC74_RS11595	COG0477	Major facilitator Superfamily
FYC74_RS11630	COG1376	ErfK ybiS ycfS ynhG family protein
FYC74_RS11645	COG2197	response regulator
FYC74_RS11650	COG4585	Histidine kinase
FYC74_RS11660	COG1131	(ABC) transporter
FYC74_RS11670	COG1132	(ABC) transporter
FYC74_RS11675	COG1132	(ABC) transporter
FYC74_RS11695	COG0058	SHG alpha-glucan phosphorylase activity
FYC74_RS11700	COG0366	Alpha amylase catalytic
FYC74_RS11705	COG0366	Alpha amylase catalytic
FYC74_RS11710	COG3281	Trehalose synthase
FYC74_RS11715	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FYC74_RS11740	COG1301	dicarboxylic acid transport
FYC74_RS11745	COG0745	RESPONSE REGULATOR receiver
FYC74_RS11745	COG4191	Histidine kinase
FYC74_RS11745	COG2205	protein histidine kinase activity
FYC74_RS11750	COG4565	transcriptional regulatory protein
FYC74_RS11755	COG1653	transport
FYC74_RS11765	COG0395	ABC-type sugar transport system, permease component
FYC74_RS11775	COG0205	6-phosphofructokinase activity
FYC74_RS11780	COG0857	belongs to the CobB CobQ family
FYC74_RS11780	COG0280	phosphate acetyltransferase
FYC74_RS11785	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FYC74_RS11825	COG4977	sequence-specific DNA binding
FYC74_RS11830	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FYC74_RS11830	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FYC74_RS11880	COG0745	RESPONSE REGULATOR receiver
FYC74_RS11895	COG0183	Belongs to the thiolase family
FYC74_RS11915	COG1131	(ABC) transporter
FYC74_RS11950	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
FYC74_RS11965	COG1250	3-hydroxyacyl-CoA dehydrogenase
FYC74_RS11980	COG4585	Histidine kinase
FYC74_RS11985	COG2197	response regulator
FYC74_RS12000	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FYC74_RS12005	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FYC74_RS12010	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FYC74_RS12015	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FYC74_RS12020	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FYC74_RS12025	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FYC74_RS12030	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FYC74_RS12050	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FYC74_RS12055	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FYC74_RS12065	COG2890	protein-(glutamine-N5) methyltransferase activity
FYC74_RS12070	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FYC74_RS12075	COG0254	rRNA binding
FYC74_RS12080	COG1316	TRANSCRIPTIONal
FYC74_RS12090	COG0083	homoserine kinase activity
FYC74_RS12095	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FYC74_RS12100	COG0460	homoserine dehydrogenase
FYC74_RS12105	COG0019	diaminopimelate decarboxylase activity
FYC74_RS12110	COG0018	arginyl-trna synthetase
FYC74_RS12115	COG0745	RESPONSE REGULATOR receiver
FYC74_RS12130	COG1196	nuclear chromosome segregation
FYC74_RS12170	COG0456	acetyltransferase
FYC74_RS12235	COG0477	Major facilitator Superfamily
FYC74_RS12235	COG2814	Major facilitator Superfamily
FYC74_RS12240	COG2186	Transcriptional regulator
FYC74_RS12250	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYC74_RS12255	COG1960	acyl-CoA dehydrogenase activity
FYC74_RS12260	COG2079	MmgE PrpD family protein
FYC74_RS12270	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FYC74_RS12275	COG2329	Antibiotic biosynthesis monooxygenase
FYC74_RS12280	COG0662	Cupin 2, conserved barrel domain protein
FYC74_RS12285	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FYC74_RS12290	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FYC74_RS12295	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FYC74_RS12300	COG2867	negative regulation of translational initiation
FYC74_RS12315	COG3467	pyridoxamine 5'-phosphate
FYC74_RS12330	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FYC74_RS12335	COG3285	dna ligase
FYC74_RS12335	COG1793	dna ligase
FYC74_RS12355	COG2205	protein histidine kinase activity
FYC74_RS12395	COG3883	PFAM NLP P60 protein
FYC74_RS12395	COG0791	NLP P60 protein
FYC74_RS12440	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FYC74_RS12450	COG0745	RESPONSE REGULATOR receiver
FYC74_RS12455	COG2205	protein histidine kinase activity
FYC74_RS12460	COG0567	Dehydrogenase, E1 component
FYC74_RS12460	COG0508	dehydrogenase complex catalyzes the overall conversion of
FYC74_RS12535	COG0281	malic enzyme
FYC74_RS12550	COG1126	abc transporter atp-binding protein
FYC74_RS12555	COG4106	trans-aconitate 2-methyltransferase activity
FYC74_RS12580	COG3842	ATPase activity
FYC74_RS12595	COG0142	geranyltranstransferase activity
FYC74_RS12600	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FYC74_RS12610	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FYC74_RS12640	COG1597	lipid kinase activity
FYC74_RS12655	COG0363	glucosamine-6-phosphate deaminase activity
FYC74_RS12660	COG1472	Belongs to the glycosyl hydrolase 3 family
FYC74_RS12665	COG0395	ABC-type sugar transport system, permease component
FYC74_RS12670	COG1175	transmembrane transport
FYC74_RS12675	COG2182	Extracellular solute-binding protein
FYC74_RS12680	COG2188	Transcriptional regulator
FYC74_RS12715	COG2124	cytochrome p450
FYC74_RS12725	COG0242	peptide deformylase activity
FYC74_RS12745	COG5662	AntiSigma factor
FYC74_RS12750	COG1595	DNA-templated transcription, initiation
FYC74_RS12760	COG2135	peptidase activity
FYC74_RS12770	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FYC74_RS12780	COG2076	Multidrug Resistance protein
FYC74_RS12790	COG0483	inositol monophosphate 1-phosphatase activity
FYC74_RS12800	COG0583	DNA-binding transcription factor activity
FYC74_RS12805	COG0183	Belongs to the thiolase family
FYC74_RS12815	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FYC74_RS12820	COG2271	Major facilitator Superfamily
FYC74_RS12830	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FYC74_RS12835	COG1024	Enoyl-CoA hydratase
FYC74_RS12845	COG1024	Enoyl-CoA hydratase
FYC74_RS12850	COG0318	PFAM AMP-dependent synthetase and ligase
FYC74_RS12860	COG0753	catalase activity
FYC74_RS12885	COG1615	UPF0182 protein
FYC74_RS12895	COG3480	Lon protease (S16) C-terminal proteolytic domain
FYC74_RS12950	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FYC74_RS12980	COG2816	NAD+ diphosphatase activity
FYC74_RS12990	COG0210	DNA helicase
FYC74_RS12995	COG0210	DNA helicase
FYC74_RS13015	COG0596	Alpha beta hydrolase
FYC74_RS13090	COG1432	Conserved Protein
FYC74_RS13100	COG2095	MarC family integral membrane protein
FYC74_RS13115	COG2814	Major facilitator Superfamily
FYC74_RS13125	COG0598	Magnesium transport protein CorA
FYC74_RS13160	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FYC74_RS13165	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FYC74_RS13175	COG1595	DNA-templated transcription, initiation
FYC74_RS13190	COG1024	Enoyl-CoA hydratase
FYC74_RS13195	COG0519	Catalyzes the synthesis of GMP from XMP
FYC74_RS13205	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FYC74_RS13215	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FYC74_RS13260	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FYC74_RS13315	COG4608	Belongs to the ABC transporter superfamily
FYC74_RS13320	COG0444	Belongs to the ABC transporter superfamily
FYC74_RS13325	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FYC74_RS13330	COG0601	transmembrane transport
FYC74_RS13340	COG4608	Belongs to the ABC transporter superfamily
FYC74_RS13345	COG0444	Belongs to the ABC transporter superfamily
FYC74_RS13355	COG4166	transmembrane transport
FYC74_RS13360	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FYC74_RS13365	COG1217	gtp-binding protein TYPA
FYC74_RS13390	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FYC74_RS13445	COG2318	DinB family
FYC74_RS13465	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FYC74_RS13475	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FYC74_RS13480	COG2197	response regulator
FYC74_RS13525	COG3629	intracellular signal transduction
FYC74_RS13530	COG2091	lysine biosynthetic process via aminoadipic acid
FYC74_RS13580	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FYC74_RS13595	COG0012	GTP binding
FYC74_RS13610	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FYC74_RS13620	COG1570	exodeoxyribonuclease VII activity
FYC74_RS13625	COG1722	exodeoxyribonuclease VII activity
FYC74_RS13630	COG0778	Nitroreductase
FYC74_RS13655	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FYC74_RS13655	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FYC74_RS13660	COG0114	fumarate hydratase activity
FYC74_RS13675	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FYC74_RS13695	COG1136	(ABC) transporter
FYC74_RS13710	COG0450	alkyl hydroperoxide reductase
FYC74_RS13715	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FYC74_RS13730	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FYC74_RS13735	COG2226	methyltransferase
FYC74_RS13760	COG0789	Transcriptional regulator
FYC74_RS13825	COG2894	cell division
FYC74_RS13885	COG2610	gluconate transmembrane transporter activity
FYC74_RS13890	COG0251	oxidation-reduction process
FYC74_RS13895	COG1414	Transcriptional regulator
FYC74_RS13910	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
FYC74_RS13915	COG0436	Aminotransferase
FYC74_RS13925	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
FYC74_RS13940	COG1331	Highly conserved protein containing a thioredoxin domain
FYC74_RS13960	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FYC74_RS13970	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FYC74_RS13985	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FYC74_RS13990	COG2255	four-way junction helicase activity
FYC74_RS14015	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FYC74_RS14030	COG0667	Aldo Keto reductase
FYC74_RS14035	COG1064	alcohol dehydrogenase
FYC74_RS14065	COG2986	histidine ammonia-lyase
FYC74_RS14075	COG1024	Enoyl-CoA hydratase
FYC74_RS14085	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
FYC74_RS14095	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FYC74_RS14105	COG0424	maF-like protein
FYC74_RS14115	COG4770	biotin carboxylase activity
FYC74_RS14140	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FYC74_RS14155	COG1012	belongs to the aldehyde dehydrogenase family
FYC74_RS14160	COG1012	belongs to the aldehyde dehydrogenase family
FYC74_RS14165	COG0515	serine threonine protein kinase
FYC74_RS14180	COG1595	DNA-templated transcription, initiation
FYC74_RS14185	COG0745	RESPONSE REGULATOR receiver
FYC74_RS14190	COG2205	protein histidine kinase activity
FYC74_RS14205	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FYC74_RS14225	COG0583	DNA-binding transcription factor activity
FYC74_RS14230	COG2814	Major facilitator Superfamily
FYC74_RS14260	COG4948	Mandelate Racemase Muconate Lactonizing
FYC74_RS14290	COG1079	Belongs to the binding-protein-dependent transport system permease family
FYC74_RS14305	COG1744	ABC transporter substrate-binding protein PnrA-like
FYC74_RS14310	COG1744	ABC transporter substrate-binding protein PnrA-like
FYC74_RS14315	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
FYC74_RS14315	COG1473	amidohydrolase
FYC74_RS14325	COG2089	acid synthase
FYC74_RS14340	COG1216	Glycosyl transferase, family 2
FYC74_RS14365	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FYC74_RS14390	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FYC74_RS14390	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FYC74_RS14405	COG1595	DNA-templated transcription, initiation
FYC74_RS14415	COG0110	maltose O-acetyltransferase activity
FYC74_RS14420	COG1309	transcriptional regulator
FYC74_RS14435	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FYC74_RS14445	COG2009	succinate dehydrogenase
FYC74_RS14455	COG1053	succinate dehydrogenase
FYC74_RS14485	COG1309	transcriptional regulator
FYC74_RS14490	COG0308	aminopeptidase N
FYC74_RS14495	COG1408	metallophosphoesterase
FYC74_RS14505	COG1686	Belongs to the peptidase S11 family
FYC74_RS14525	COG0671	phosphoesterase, PA-phosphatase related
FYC74_RS14545	COG0180	Tryptophanyl-tRNA synthetase
FYC74_RS14550	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FYC74_RS14555	COG0754	glutathionylspermidine amidase activity
FYC74_RS14565	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FYC74_RS14570	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FYC74_RS14575	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FYC74_RS14585	COG4176	ABC-type proline glycine betaine transport system permease component
FYC74_RS14600	COG1012	belongs to the aldehyde dehydrogenase family
FYC74_RS14605	COG0039	L-malate dehydrogenase activity
FYC74_RS14620	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FYC74_RS14640	COG0138	bifunctional purine biosynthesis protein purh
FYC74_RS14670	COG0045	succinate-CoA ligase (ADP-forming) activity
FYC74_RS14680	COG3552	Protein containing von Willebrand factor type A (VWA) domain
FYC74_RS14690	COG0714	Associated with various cellular activities
FYC74_RS14705	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FYC74_RS14715	COG0739	heme binding
FYC74_RS14745	COG2197	response regulator
FYC74_RS14785	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FYC74_RS14785	COG0519	Catalyzes the synthesis of GMP from XMP
FYC74_RS14800	COG1012	belongs to the aldehyde dehydrogenase family
FYC74_RS14805	COG0515	serine threonine protein kinase
FYC74_RS14815	COG0515	serine threonine protein kinase
FYC74_RS14820	COG0515	serine threonine protein kinase
FYC74_RS14825	COG2815	serine threonine protein kinase
FYC74_RS14825	COG0515	serine threonine protein kinase
FYC74_RS14835	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FYC74_RS14850	COG0516	GMP reductase activity
FYC74_RS14860	COG1595	DNA-templated transcription, initiation
FYC74_RS14875	COG0583	DNA-binding transcription factor activity
FYC74_RS14885	COG4221	oxidoreductase activity
FYC74_RS14895	COG0459	protein refolding
FYC74_RS14900	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FYC74_RS14905	COG0726	polysaccharide deacetylase
FYC74_RS14910	COG0726	polysaccharide deacetylase
FYC74_RS14920	COG4941	Belongs to the sigma-70 factor family
FYC74_RS14965	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FYC74_RS14990	COG0802	atpase or kinase
FYC74_RS15000	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FYC74_RS15005	COG0736	holo-[acyl-carrier-protein] synthase activity
FYC74_RS15045	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FYC74_RS15055	COG1072	(Pantothenic acid kinase))
FYC74_RS15065	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FYC74_RS15070	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FYC74_RS15075	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FYC74_RS15090	COG0101	tRNA pseudouridine synthase activity
FYC74_RS15095	COG0203	ribosomal protein L17
FYC74_RS15100	COG0202	RNA polymerase activity
FYC74_RS15105	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FYC74_RS15110	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FYC74_RS15115	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FYC74_RS15120	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FYC74_RS15130	COG0563	adenylate kinase activity
FYC74_RS15135	COG0201	protein transport
FYC74_RS15140	COG0200	Binds to the 23S rRNA
FYC74_RS15145	COG1841	ribosomal large subunit assembly
FYC74_RS15150	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FYC74_RS15155	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FYC74_RS15160	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FYC74_RS15165	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FYC74_RS15170	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FYC74_RS15175	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FYC74_RS15180	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FYC74_RS15185	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FYC74_RS15190	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FYC74_RS15195	COG0255	Belongs to the universal ribosomal protein uL29 family
FYC74_RS15200	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FYC74_RS15205	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FYC74_RS15210	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FYC74_RS15215	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FYC74_RS15220	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FYC74_RS15225	COG0089	rRNA binding
FYC74_RS15230	COG0088	Forms part of the polypeptide exit tunnel
FYC74_RS15235	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FYC74_RS15240	COG0051	transcription antitermination factor activity, RNA binding
FYC74_RS15250	COG4104	PAAR repeat-containing protein
FYC74_RS15250	COG3209	COG3209 Rhs family protein
FYC74_RS15285	COG0702	epimerase
FYC74_RS15320	COG0513	Belongs to the DEAD box helicase family
FYC74_RS15325	COG1278	Cold shock
FYC74_RS15330	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FYC74_RS15340	COG1028	Short-chain dehydrogenase reductase Sdr
FYC74_RS15375	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FYC74_RS15380	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FYC74_RS15385	COG0049	tRNA binding
FYC74_RS15390	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FYC74_RS15405	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FYC74_RS15410	COG0085	RNA polymerase activity
FYC74_RS15415	COG0222	ribosome binding
FYC74_RS15420	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FYC74_RS15435	COG0081	regulation of translation
FYC74_RS15440	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FYC74_RS15445	COG0250	Participates in transcription elongation, termination and antitermination
FYC74_RS15450	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FYC74_RS15460	COG0436	Aminotransferase
FYC74_RS15465	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FYC74_RS15470	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FYC74_RS15495	COG2030	dehydratase
FYC74_RS15500	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FYC74_RS15515	COG0402	S-adenosylhomocysteine deaminase activity
FYC74_RS15520	COG0702	epimerase
FYC74_RS15535	COG1666	GTP binding
FYC74_RS15540	COG2261	transglycosylase associated protein
FYC74_RS15545	COG3304	Inner membrane component domain
FYC74_RS15550	COG0501	Belongs to the peptidase M48B family
FYC74_RS15555	COG1007	ATP synthesis coupled electron transport
FYC74_RS15565	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FYC74_RS15570	COG0713	ATP synthesis coupled electron transport
FYC74_RS15580	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FYC74_RS15585	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FYC74_RS15590	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FYC74_RS15595	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FYC74_RS15600	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FYC74_RS15620	COG0674	pyruvate-flavodoxin oxidoreductase activity
FYC74_RS15620	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FYC74_RS15625	COG1013	pyruvate-flavodoxin oxidoreductase activity
FYC74_RS15630	COG0702	epimerase
FYC74_RS15655	COG0655	NAD(P)H dehydrogenase (quinone) activity
FYC74_RS15665	COG1131	(ABC) transporter
FYC74_RS15675	COG0142	geranyltranstransferase activity
FYC74_RS15685	COG0561	phosphatase activity
FYC74_RS15725	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FYC74_RS15740	COG0514	ATP-dependent DNA helicase (RecQ)
FYC74_RS15750	COG1007	ATP synthesis coupled electron transport
FYC74_RS15760	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FYC74_RS15765	COG0713	ATP synthesis coupled electron transport
FYC74_RS15775	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FYC74_RS15780	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FYC74_RS15785	COG1034	ATP synthesis coupled electron transport
FYC74_RS15790	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FYC74_RS15800	COG0649	NAD binding
FYC74_RS15805	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FYC74_RS15810	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FYC74_RS15830	COG0242	peptide deformylase activity
FYC74_RS15850	COG2226	methyltransferase
FYC74_RS15880	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FYC74_RS16025	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
FYC74_RS16130	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
FYC74_RS16135	COG1278	Cold shock
FYC74_RS16140	COG2226	methyltransferase
FYC74_RS16150	COG0183	Belongs to the thiolase family
FYC74_RS16165	COG1309	transcriptional regulator
FYC74_RS16175	COG1301	dicarboxylic acid transport
FYC74_RS16190	COG1573	uracil-dna glycosylase
FYC74_RS16195	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FYC74_RS16205	COG0163	prenyltransferase activity
FYC74_RS16210	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FYC74_RS16215	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FYC74_RS16235	COG0583	DNA-binding transcription factor activity
FYC74_RS16250	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FYC74_RS16255	COG1333	cytochrome c biogenesis protein
FYC74_RS16260	COG0785	Cytochrome C biogenesis protein
FYC74_RS16265	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FYC74_RS16275	COG0406	alpha-ribazole phosphatase activity
FYC74_RS16280	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FYC74_RS16290	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FYC74_RS16325	COG1309	transcriptional regulator
FYC74_RS16360	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
FYC74_RS16375	COG0583	DNA-binding transcription factor activity
FYC74_RS16385	COG1028	Short-chain dehydrogenase reductase Sdr
FYC74_RS16390	COG1309	transcriptional regulator
FYC74_RS16440	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FYC74_RS16495	COG0745	RESPONSE REGULATOR receiver
FYC74_RS16500	COG0431	NADPH-dependent FMN reductase
FYC74_RS16505	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FYC74_RS16510	COG1742	UPF0060 membrane protein
FYC74_RS16520	COG1690	Belongs to the RtcB family
FYC74_RS16540	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
FYC74_RS16545	COG0018	arginyl-trna synthetase
FYC74_RS16565	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FYC74_RS16580	COG0113	porphobilinogen synthase activity
FYC74_RS16585	COG0604	alcohol dehydrogenase
FYC74_RS16585	COG3321	synthase
FYC74_RS16615	COG1648	precorrin-2 dehydrogenase activity
FYC74_RS16615	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FYC74_RS16620	COG0181	hydroxymethylbilane synthase activity
FYC74_RS16625	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FYC74_RS16630	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
FYC74_RS16680	COG0123	including yeast histone deacetylase and acetoin utilization protein
FYC74_RS16685	COG2223	nitrite transmembrane transporter activity
FYC74_RS16695	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FYC74_RS16715	COG0180	Tryptophanyl-tRNA synthetase
FYC74_RS16720	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FYC74_RS16730	COG1129	ABC transporter
FYC74_RS16730	COG0842	Transport permease protein
FYC74_RS16760	COG0129	dihydroxy-acid dehydratase activity
FYC74_RS16770	COG1082	Xylose isomerase domain protein TIM barrel
FYC74_RS16775	COG0248	Ppx GppA phosphatase
FYC74_RS16795	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
FYC74_RS16805	COG1194	a g-specific adenine glycosylase
FYC74_RS16810	COG1595	DNA-templated transcription, initiation
FYC74_RS16820	COG0745	RESPONSE REGULATOR receiver
FYC74_RS16825	COG2205	protein histidine kinase activity
FYC74_RS16860	COG0739	heme binding
FYC74_RS16895	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FYC74_RS16915	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FYC74_RS16930	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FYC74_RS16940	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
FYC74_RS16950	COG1660	Displays ATPase and GTPase activities
FYC74_RS16955	COG2197	response regulator
FYC74_RS16970	COG0649	NAD binding
FYC74_RS17005	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FYC74_RS17010	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FYC74_RS17020	COG0302	gtp cyclohydrolase
FYC74_RS17035	COG0037	tRNA processing
FYC74_RS17045	COG2027	D-alanyl-D-alanine carboxypeptidase
FYC74_RS17050	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FYC74_RS17060	COG0586	Pfam SNARE associated Golgi protein
FYC74_RS17065	COG0393	Putative heavy-metal-binding
FYC74_RS17070	COG0789	Transcriptional regulator
FYC74_RS17075	COG0076	glutamate decarboxylase activity
FYC74_RS17090	COG1012	belongs to the aldehyde dehydrogenase family
FYC74_RS17110	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FYC74_RS17120	COG0254	rRNA binding
FYC74_RS17125	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FYC74_RS17130	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FYC74_RS17135	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FYC74_RS17155	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FYC74_RS17155	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FYC74_RS17160	COG2197	response regulator
FYC74_RS17165	COG4585	Histidine kinase
FYC74_RS17175	COG1309	transcriptional regulator
FYC74_RS17180	COG2815	serine threonine protein kinase
FYC74_RS17180	COG0515	serine threonine protein kinase
FYC74_RS17235	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FYC74_RS17240	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FYC74_RS17245	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FYC74_RS17245	COG1754	DNA topoisomerase type I activity
FYC74_RS17265	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
FYC74_RS17270	COG2172	sigma factor antagonist activity
FYC74_RS17275	COG1366	Belongs to the anti-sigma-factor antagonist family
FYC74_RS17340	COG0659	secondary active sulfate transmembrane transporter activity
FYC74_RS17345	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FYC74_RS17350	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FYC74_RS17360	COG0596	Alpha beta hydrolase
FYC74_RS17370	COG0494	nUDIX hydrolase
FYC74_RS17385	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FYC74_RS17395	COG0596	Alpha beta hydrolase
FYC74_RS17415	COG0003	Pfam Anion-transporting ATPase
FYC74_RS17425	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FYC74_RS17435	COG1408	metallophosphoesterase
FYC74_RS17570	COG1205	dead DEAH box helicase
FYC74_RS17570	COG1111	helicase
FYC74_RS17575	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FYC74_RS17580	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FYC74_RS17590	COG1401	restriction endodeoxyribonuclease activity
FYC74_RS17650	COG1668	transmembrane transport
FYC74_RS17655	COG4152	abc transporter atp-binding protein
FYC74_RS17670	COG1131	(ABC) transporter
FYC74_RS17695	COG2274	protein secretion by the type I secretion system
FYC74_RS17735	COG0542	response to heat
FYC74_RS17800	COG0577	efflux transmembrane transporter activity
FYC74_RS17800	COG1136	(ABC) transporter
FYC74_RS17855	COG0475	glutathione-regulated potassium exporter activity
FYC74_RS17860	COG3263	regulation of cellular component size
FYC74_RS17870	COG3655	Transcriptional regulator
FYC74_RS17880	COG2268	Band 7 protein
FYC74_RS17885	COG1585	Membrane protein implicated in regulation of membrane protease activity
FYC74_RS17895	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FYC74_RS17905	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FYC74_RS17910	COG0640	Transcriptional regulator
FYC74_RS17935	COG1595	DNA-templated transcription, initiation
FYC74_RS17975	COG2124	cytochrome p450
FYC74_RS17985	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FYC74_RS17990	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FYC74_RS18005	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FYC74_RS18010	COG1802	Transcriptional regulator
FYC74_RS18030	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FYC74_RS18045	COG1131	(ABC) transporter
FYC74_RS18050	COG3559	Exporter of polyketide antibiotics
FYC74_RS18065	COG2197	response regulator
FYC74_RS18070	COG4585	Histidine kinase
FYC74_RS18075	COG2197	response regulator
FYC74_RS18080	COG4585	Histidine kinase
FYC74_RS18100	COG3844	kynureninase activity
FYC74_RS18115	COG0477	Major facilitator Superfamily
FYC74_RS18120	COG0191	fructose-bisphosphate aldolase activity
FYC74_RS18125	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FYC74_RS18140	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FYC74_RS18160	COG0596	Alpha beta hydrolase
FYC74_RS18175	COG0542	response to heat
FYC74_RS18205	COG4213	ABC transporter substrate-binding protein
FYC74_RS18210	COG0789	Transcriptional regulator
FYC74_RS18215	COG0484	heat shock protein binding
FYC74_RS18220	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FYC74_RS18225	COG0443	Heat shock 70 kDa protein
FYC74_RS18230	COG0247	lactate metabolic process
FYC74_RS18230	COG2181	nitrate reductase activity
FYC74_RS18245	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FYC74_RS18250	COG0717	Belongs to the dCTP deaminase family
FYC74_RS18310	COG0142	geranyltranstransferase activity
FYC74_RS18345	COG1733	regulation of RNA biosynthetic process
FYC74_RS18440	COG0667	Aldo Keto reductase
FYC74_RS18445	COG1278	Cold shock
FYC74_RS18450	COG0513	Belongs to the DEAD box helicase family
FYC74_RS18485	COG5002	protein histidine kinase activity
FYC74_RS18540	COG4585	Histidine kinase
FYC74_RS18550	COG1136	(ABC) transporter
FYC74_RS18550	COG0577	efflux transmembrane transporter activity
FYC74_RS18560	COG0596	Alpha beta hydrolase
FYC74_RS18575	COG1136	(ABC) transporter
FYC74_RS18580	COG2197	response regulator
FYC74_RS18585	COG4585	Histidine kinase
FYC74_RS18610	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FYC74_RS18625	COG0583	DNA-binding transcription factor activity
FYC74_RS18645	COG0366	Alpha amylase catalytic
FYC74_RS18700	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FYC74_RS18710	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FYC74_RS18785	COG1741	Belongs to the pirin family
FYC74_RS18795	COG1960	acyl-CoA dehydrogenase activity
FYC74_RS18800	COG1362	aminopeptidase activity
FYC74_RS18845	COG0508	dehydrogenase complex catalyzes the overall conversion of
FYC74_RS18850	COG0022	dehydrogenase e1 component
FYC74_RS18870	COG0515	serine threonine protein kinase
FYC74_RS18875	COG0515	serine threonine protein kinase
FYC74_RS18890	COG1028	Short-chain dehydrogenase reductase Sdr
FYC74_RS18890	COG3321	synthase
FYC74_RS18890	COG0604	alcohol dehydrogenase
FYC74_RS18935	COG1522	sequence-specific DNA binding
FYC74_RS18940	COG1309	transcriptional regulator
FYC74_RS18945	COG1250	3-hydroxyacyl-CoA dehydrogenase
FYC74_RS18990	COG1716	ATPase activity
FYC74_RS18995	COG1716	ATPase activity
FYC74_RS19010	COG0768	penicillin binding
FYC74_RS19015	COG0515	serine threonine protein kinase
FYC74_RS19020	COG3764	Sortase (surface protein transpeptidase)
FYC74_RS19025	COG3764	Sortase (surface protein transpeptidase)
FYC74_RS19050	COG0705	Rhomboid family
FYC74_RS19065	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FYC74_RS19105	COG2319	Wd-40 repeat
FYC74_RS19105	COG4249	Peptidase C14 caspase catalytic subunit p20
FYC74_RS19130	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FYC74_RS19135	COG0187	DNA topoisomerase II activity
FYC74_RS19140	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
FYC74_RS19145	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FYC74_RS19150	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FYC74_RS19155	COG0592	DNA-directed DNA polymerase activity
FYC74_RS19160	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FYC74_RS19165	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FYC74_RS19170	COG0594	ribonuclease P activity
FYC74_RS19175	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FYC74_RS19180	COG0706	membrane insertase activity
FYC74_RS19190	COG0357	Ribosomal RNA small subunit methyltransferase G
FYC74_RS19195	COG1192	Involved in chromosome partitioning
FYC74_RS19210	COG3118	belongs to the thioredoxin family
FYC74_RS19215	COG0492	ferredoxin-NADP+ reductase activity
FYC74_RS19225	COG1595	DNA-templated transcription, initiation
FYC74_RS19245	COG0617	tRNA 3'-terminal CCA addition
FYC74_RS19270	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FYC74_RS19295	COG0360	Binds together with S18 to 16S ribosomal RNA
FYC74_RS19300	COG0629	single-stranded DNA binding
FYC74_RS19305	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FYC74_RS19310	COG0359	binds to the 23S rRNA
FYC74_RS19320	COG0305	Participates in initiation and elongation during chromosome replication
FYC74_RS19330	COG4585	Histidine kinase
FYC74_RS19335	COG2197	response regulator
FYC74_RS19355	COG2814	Major facilitator Superfamily
FYC74_RS19380	COG0626	cystathionine gamma-synthase activity
FYC74_RS19385	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FYC74_RS19390	COG1950	PFAM Membrane protein of
FYC74_RS19395	COG0662	Cupin 2, conserved barrel domain protein
FYC74_RS19420	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FYC74_RS19435	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FYC74_RS19440	COG1609	Transcriptional regulator
FYC74_RS19445	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FYC74_RS19450	COG1271	oxidase subunit
FYC74_RS19455	COG1294	oxidase, subunit
FYC74_RS19460	COG4988	ABC transporter
FYC74_RS19470	COG0739	heme binding
FYC74_RS19475	COG0561	phosphatase activity
FYC74_RS19485	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
FYC74_RS19495	COG1131	(ABC) transporter
FYC74_RS19520	COG0561	phosphatase activity
FYC74_RS19525	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FYC74_RS19530	COG0077	Prephenate dehydratase
FYC74_RS19535	COG2837	iron assimilation
FYC74_RS19550	COG1999	signal sequence binding
FYC74_RS19570	COG0006	proline dipeptidase activity
FYC74_RS19590	COG0653	protein targeting
FYC74_RS19605	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FYC74_RS19630	COG1595	DNA-templated transcription, initiation
FYC74_RS19635	COG0318	PFAM AMP-dependent synthetase and ligase
FYC74_RS19640	COG2814	Major facilitator Superfamily
FYC74_RS19645	COG1309	transcriptional regulator
FYC74_RS19650	COG0784	Response regulator, receiver
FYC74_RS19680	COG0768	penicillin binding
FYC74_RS19685	COG1733	regulation of RNA biosynthetic process
FYC74_RS19715	COG0745	RESPONSE REGULATOR receiver
FYC74_RS19720	COG2205	protein histidine kinase activity
FYC74_RS19730	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FYC74_RS19730	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FYC74_RS19740	COG0477	Major facilitator Superfamily
FYC74_RS19750	COG3467	pyridoxamine 5'-phosphate
FYC74_RS19770	COG2353	YceI-like domain
FYC74_RS19790	COG1191	sigma factor activity
FYC74_RS19795	COG1191	sigma factor activity
FYC74_RS19835	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FYC74_RS19915	COG0151	Belongs to the GarS family
FYC74_RS19930	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FYC74_RS19940	COG2197	response regulator
FYC74_RS19975	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FYC74_RS19980	COG0047	phosphoribosylformylglycinamidine synthase activity
FYC74_RS19985	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FYC74_RS20010	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FYC74_RS20020	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FYC74_RS20040	COG1643	Atp-dependent helicase
FYC74_RS20075	COG0513	Belongs to the DEAD box helicase family
FYC74_RS20105	COG2860	membrane
FYC74_RS20115	COG1414	Transcriptional regulator
FYC74_RS20210	COG1201	RNA secondary structure unwinding
FYC74_RS20215	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FYC74_RS20215	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FYC74_RS20245	COG0667	Aldo Keto reductase
FYC74_RS20255	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FYC74_RS20260	COG0579	oxidoreductase
FYC74_RS20290	COG1252	NADH dehydrogenase
FYC74_RS20325	COG2197	response regulator
FYC74_RS20330	COG4585	Histidine kinase
FYC74_RS20370	COG1196	nuclear chromosome segregation
FYC74_RS20370	COG0741	lytic transglycosylase activity
FYC74_RS20370	COG0739	heme binding
FYC74_RS20375	COG0671	phosphoesterase, PA-phosphatase related
FYC74_RS20380	COG0277	FAD linked oxidase domain protein
FYC74_RS20395	COG1937	Protein conserved in bacteria
FYC74_RS20405	COG0306	phosphate transporter
FYC74_RS20410	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FYC74_RS20440	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FYC74_RS20470	COG0456	acetyltransferase
FYC74_RS20490	COG0745	RESPONSE REGULATOR receiver
FYC74_RS20495	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FYC74_RS20500	COG1609	Transcriptional regulator
FYC74_RS20505	COG0745	RESPONSE REGULATOR receiver
FYC74_RS20530	COG2897	thiosulfate sulfurtransferase activity
FYC74_RS20590	COG3485	protocatechuate 3,4-dioxygenase
FYC74_RS20595	COG0735	belongs to the Fur family
FYC74_RS20600	COG0354	folic acid binding
FYC74_RS20605	COG1490	D-aminoacyl-tRNA deacylase activity
FYC74_RS20635	COG0546	phosphoglycolate phosphatase activity
FYC74_RS20680	COG0791	NLP P60 protein
FYC74_RS20690	COG0438	transferase activity, transferring glycosyl groups
FYC74_RS20715	COG0588	phosphoglycerate mutase activity
FYC74_RS20725	COG2188	Transcriptional regulator
FYC74_RS20755	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FYC74_RS20805	COG2130	NADP-dependent
FYC74_RS20840	COG3104	oligopeptide transport
FYC74_RS20850	COG2207	Transcriptional regulator
FYC74_RS20850	COG3708	Transcriptional regulator
FYC74_RS20875	COG5002	protein histidine kinase activity
FYC74_RS20890	COG1329	Transcriptional regulator
FYC74_RS20895	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FYC74_RS20900	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FYC74_RS20905	COG0215	cysteine-tRNA ligase activity
FYC74_RS20950	COG3842	ATPase activity
FYC74_RS20960	COG2890	protein-(glutamine-N5) methyltransferase activity
FYC74_RS21055	COG0464	growth
FYC74_RS21070	COG2197	response regulator
FYC74_RS21080	COG0702	epimerase
FYC74_RS21085	COG3631	Ketosteroid isomerase-related protein
FYC74_RS21110	COG1215	transferase activity, transferring glycosyl groups
FYC74_RS21125	COG1309	transcriptional regulator
FYC74_RS21130	COG1064	alcohol dehydrogenase
FYC74_RS21145	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FYC74_RS21165	COG3300	MHYT domain
FYC74_RS21165	COG5001	Diguanylate cyclase
FYC74_RS21175	COG1105	Belongs to the carbohydrate kinase PfkB family
FYC74_RS21220	COG0463	Glycosyl transferase, family 2
FYC74_RS21235	COG1278	Cold shock
FYC74_RS21240	COG0459	protein refolding
FYC74_RS21255	COG1309	transcriptional regulator
FYC74_RS21260	COG1028	Short-chain dehydrogenase reductase Sdr
FYC74_RS21270	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FYC74_RS21275	COG1737	Transcriptional regulator
FYC74_RS21310	COG3973	AAA domain
FYC74_RS21320	COG1061	Type III restriction enzyme res subunit
FYC74_RS21345	COG1278	Cold shock
FYC74_RS21350	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
FYC74_RS21355	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FYC74_RS21365	COG2814	Major facilitator Superfamily
FYC74_RS21380	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FYC74_RS21390	COG2252	PERMEase
FYC74_RS21415	COG0667	Aldo Keto reductase
FYC74_RS21460	COG2197	response regulator
FYC74_RS21530	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FYC74_RS21535	COG0247	lactate metabolic process
FYC74_RS21535	COG0277	FAD linked oxidase domain protein
FYC74_RS21540	COG2318	DinB family
FYC74_RS21565	COG1309	transcriptional regulator
FYC74_RS21570	COG0604	alcohol dehydrogenase
FYC74_RS21610	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FYC74_RS21625	COG0318	PFAM AMP-dependent synthetase and ligase
FYC74_RS21640	COG0259	pyridoxamine-phosphate oxidase activity
FYC74_RS21655	COG4821	SIS domain
FYC74_RS21665	COG2945	thiolester hydrolase activity
FYC74_RS21665	COG0596	Alpha beta hydrolase
FYC74_RS21675	COG1131	(ABC) transporter
FYC74_RS21715	COG1595	DNA-templated transcription, initiation
FYC74_RS21720	COG1366	Belongs to the anti-sigma-factor antagonist family
FYC74_RS21755	COG0259	pyridoxamine-phosphate oxidase activity
FYC74_RS21765	COG1309	transcriptional regulator
FYC74_RS21775	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FYC74_RS21775	COG0515	serine threonine protein kinase
FYC74_RS21795	COG3903	Transcriptional regulator
FYC74_RS21795	COG3629	intracellular signal transduction
FYC74_RS21815	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FYC74_RS21850	COG1686	Belongs to the peptidase S11 family
FYC74_RS21870	COG0386	Belongs to the glutathione peroxidase family
FYC74_RS21885	COG2208	phosphoserine phosphatase activity
FYC74_RS21890	COG0745	RESPONSE REGULATOR receiver
FYC74_RS21895	COG2205	protein histidine kinase activity
FYC74_RS21945	COG1414	Transcriptional regulator
FYC74_RS21965	COG1846	Transcriptional regulator
FYC74_RS21970	COG3384	dioxygenase
FYC74_RS21975	COG1247	-acetyltransferase
FYC74_RS21980	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FYC74_RS21995	COG1349	DNA-binding transcription factor activity
FYC74_RS22005	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FYC74_RS22005	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FYC74_RS22005	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FYC74_RS22015	COG3191	aminopeptidase activity
FYC74_RS22030	COG1970	mechanosensitive ion channel activity
FYC74_RS22040	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FYC74_RS22065	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FYC74_RS22070	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FYC74_RS22080	COG0315	cyclic pyranopterin monophosphate synthase activity
FYC74_RS22085	COG0521	Mo-molybdopterin cofactor biosynthetic process
FYC74_RS22085	COG0315	cyclic pyranopterin monophosphate synthase activity
FYC74_RS22090	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FYC74_RS22115	COG0708	Exodeoxyribonuclease III
FYC74_RS22125	COG2072	flavoprotein involved in K transport
FYC74_RS22130	COG2267	carboxylic ester hydrolase activity
FYC74_RS22145	COG0793	Belongs to the peptidase S41A family
FYC74_RS22145	COG4946	Tricorn protease homolog
FYC74_RS22155	COG2409	Drug exporters of the RND superfamily
FYC74_RS22170	COG0154	amidase activity
FYC74_RS22190	COG1960	acyl-CoA dehydrogenase activity
FYC74_RS22205	COG2175	clavaminate synthase activity
FYC74_RS22210	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FYC74_RS22215	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FYC74_RS22220	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FYC74_RS22225	COG0442	prolyl-tRNA aminoacylation
FYC74_RS22235	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FYC74_RS22240	COG1122	ATPase activity
FYC74_RS22250	COG0310	cobalt ion transport
FYC74_RS22295	COG0300	oxidoreductase activity
FYC74_RS22310	COG1028	Short-chain dehydrogenase reductase Sdr
FYC74_RS22360	COG0084	hydrolase, TatD family'
FYC74_RS22370	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FYC74_RS22375	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FYC74_RS22385	COG0488	(ABC) transporter
FYC74_RS22425	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FYC74_RS22465	COG2197	response regulator
FYC74_RS22475	COG4106	trans-aconitate 2-methyltransferase activity
FYC74_RS22485	COG1309	transcriptional regulator
FYC74_RS22495	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FYC74_RS22505	COG0193	aminoacyl-tRNA hydrolase activity
FYC74_RS22510	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FYC74_RS22515	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FYC74_RS22520	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FYC74_RS22530	COG4585	Histidine kinase
FYC74_RS22560	COG1136	(ABC) transporter
FYC74_RS22565	COG0577	efflux transmembrane transporter activity
FYC74_RS22610	COG0148	phosphopyruvate hydratase activity
FYC74_RS22630	COG1252	NADH dehydrogenase
FYC74_RS22635	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FYC74_RS22640	COG0577	efflux transmembrane transporter activity
FYC74_RS22645	COG1136	(ABC) transporter
FYC74_RS22720	COG0183	Belongs to the thiolase family
FYC74_RS22725	COG2755	lipolytic protein G-D-S-L family
FYC74_RS22760	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FYC74_RS22770	COG1228	amidohydrolase
FYC74_RS22775	COG1191	sigma factor activity
FYC74_RS22780	COG1366	Belongs to the anti-sigma-factor antagonist family
FYC74_RS22790	COG3104	oligopeptide transport
FYC74_RS22795	COG0745	RESPONSE REGULATOR receiver
FYC74_RS22800	COG2205	protein histidine kinase activity
FYC74_RS22815	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FYC74_RS22835	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FYC74_RS22855	COG1316	TRANSCRIPTIONal
FYC74_RS22860	COG1316	TRANSCRIPTIONal
FYC74_RS22865	COG1316	TRANSCRIPTIONal
FYC74_RS22870	COG1316	TRANSCRIPTIONal
FYC74_RS22875	COG1316	TRANSCRIPTIONal
FYC74_RS22880	COG1316	TRANSCRIPTIONal
FYC74_RS22885	COG1316	TRANSCRIPTIONal
FYC74_RS22910	COG0778	Nitroreductase
FYC74_RS22910	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
FYC74_RS22915	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FYC74_RS22955	COG1620	l-lactate permease
FYC74_RS22960	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FYC74_RS22965	COG2835	tetraacyldisaccharide 4'-kinase activity
FYC74_RS22975	COG1482	cell wall glycoprotein biosynthetic process
FYC74_RS22985	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FYC74_RS23025	COG0714	Associated with various cellular activities
FYC74_RS23045	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
FYC74_RS23050	COG0745	RESPONSE REGULATOR receiver
FYC74_RS23055	COG5000	phosphorelay sensor kinase activity
FYC74_RS23055	COG5002	protein histidine kinase activity
FYC74_RS23070	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FYC74_RS23075	COG2197	response regulator
FYC74_RS23080	COG3214	Protein conserved in bacteria
FYC74_RS23090	COG0653	protein targeting
FYC74_RS23110	COG2902	Dehydrogenase
FYC74_RS23115	COG1216	Glycosyl transferase, family 2
FYC74_RS23120	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FYC74_RS23125	COG1134	teichoic acid transport
FYC74_RS23150	COG2318	DinB family
FYC74_RS23165	COG1846	Transcriptional regulator
FYC74_RS23170	COG1764	response to oxidative stress
FYC74_RS23180	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FYC74_RS23185	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FYC74_RS23200	COG0395	ABC-type sugar transport system, permease component
FYC74_RS23205	COG1175	transmembrane transport
FYC74_RS23220	COG0515	serine threonine protein kinase
FYC74_RS23225	COG0515	serine threonine protein kinase
FYC74_RS23230	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FYC74_RS23245	COG2884	Cell division ATP-binding protein ftsE
FYC74_RS23255	COG0793	Belongs to the peptidase S41A family
FYC74_RS23260	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FYC74_RS23300	COG2223	nitrite transmembrane transporter activity
FYC74_RS23325	COG3973	AAA domain
FYC74_RS23335	COG0776	regulation of translation
FYC74_RS23340	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FYC74_RS23345	COG1678	Uncharacterized ACR, COG1678
FYC74_RS23355	COG1653	transport
FYC74_RS23360	COG1175	transmembrane transport
FYC74_RS23365	COG0395	ABC-type sugar transport system, permease component
FYC74_RS23370	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FYC74_RS23385	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FYC74_RS23395	COG2732	(Barnase) inhibitor
FYC74_RS23425	COG2207	Transcriptional regulator
FYC74_RS23430	COG2223	nitrite transmembrane transporter activity
FYC74_RS23435	COG3480	Lon protease (S16) C-terminal proteolytic domain
FYC74_RS23445	COG1174	glycine betaine transport
FYC74_RS23455	COG1174	glycine betaine transport
FYC74_RS23465	COG3185	4-Hydroxyphenylpyruvate dioxygenase
FYC74_RS23475	COG0277	FAD linked oxidase domain protein
FYC74_RS23490	COG1714	RDD family
FYC74_RS23510	COG1335	isochorismatase
FYC74_RS23520	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FYC74_RS23530	COG1113	amino acid transport
FYC74_RS23555	COG1234	tRNA 3'-trailer cleavage
FYC74_RS23560	COG1263	PTS System
FYC74_RS23565	COG1263	PTS System
FYC74_RS23570	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FYC74_RS23575	COG2353	YceI-like domain
FYC74_RS23580	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FYC74_RS23590	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FYC74_RS23620	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FYC74_RS23635	COG4555	ABC transporter
FYC74_RS23645	COG3119	arylsulfatase activity
FYC74_RS23650	COG1940	carbohydrate kinase activity
FYC74_RS23660	COG2733	membrane
FYC74_RS23685	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FYC74_RS23765	COG1902	pentaerythritol trinitrate reductase activity
FYC74_RS23775	COG1063	alcohol dehydrogenase
FYC74_RS23840	COG1074	ATP-dependent DNA helicase activity
FYC74_RS23905	COG1028	Short-chain dehydrogenase reductase Sdr
FYC74_RS23910	COG1309	transcriptional regulator
FYC74_RS23935	COG4702	Belongs to the UPF0303 family
FYC74_RS23940	COG0673	inositol 2-dehydrogenase activity
FYC74_RS23945	COG2188	Transcriptional regulator
FYC74_RS23950	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FYC74_RS23955	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FYC74_RS24025	COG3397	chitin binding
FYC74_RS24040	COG1126	abc transporter atp-binding protein
FYC74_RS24045	COG0765	amino acid transport
FYC74_RS24050	COG0765	amino acid transport
FYC74_RS24055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FYC74_RS24120	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FYC74_RS24150	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FYC74_RS24220	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FYC74_RS24230	COG0745	RESPONSE REGULATOR receiver
FYC74_RS24240	COG3979	chitinase
FYC74_RS24265	COG0395	ABC-type sugar transport system, permease component
FYC74_RS24285	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FYC74_RS24290	COG4977	sequence-specific DNA binding
FYC74_RS24300	COG0589	response to stress
FYC74_RS24305	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FYC74_RS24325	COG1960	acyl-CoA dehydrogenase activity
FYC74_RS24340	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FYC74_RS24345	COG1309	transcriptional regulator
FYC74_RS24355	COG1946	Acyl-CoA thioesterase
FYC74_RS24370	COG0028	Belongs to the TPP enzyme family
FYC74_RS24375	COG2356	endonuclease I
FYC74_RS24380	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FYC74_RS24390	COG1309	transcriptional regulator
FYC74_RS24460	COG1472	Belongs to the glycosyl hydrolase 3 family
FYC74_RS24485	COG0673	inositol 2-dehydrogenase activity
FYC74_RS24500	COG1869	D-ribose catabolic process
FYC74_RS24505	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FYC74_RS24510	COG1879	ABC-type sugar transport system periplasmic component
FYC74_RS24515	COG1129	ABC transporter
FYC74_RS24530	COG1595	DNA-templated transcription, initiation
FYC74_RS24555	COG0477	Major facilitator Superfamily
FYC74_RS24575	COG2072	flavoprotein involved in K transport
FYC74_RS24580	COG1595	DNA-templated transcription, initiation
FYC74_RS24590	COG1131	(ABC) transporter
FYC74_RS24625	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FYC74_RS24710	COG0438	transferase activity, transferring glycosyl groups
FYC74_RS24730	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FYC74_RS24765	COG2304	oxidoreductase activity
FYC74_RS24780	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FYC74_RS24790	COG1136	(ABC) transporter
FYC74_RS24815	COG0629	single-stranded DNA binding
FYC74_RS24855	COG2249	NAD(P)H dehydrogenase (quinone) activity
FYC74_RS24865	COG0537	adenosine 5'-monophosphoramidase activity
FYC74_RS24900	COG3850	Histidine kinase
FYC74_RS24955	COG0577	efflux transmembrane transporter activity
FYC74_RS24955	COG1136	(ABC) transporter
FYC74_RS24975	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FYC74_RS24995	COG0515	serine threonine protein kinase
FYC74_RS25005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FYC74_RS25020	COG1486	melibiose metabolic process
FYC74_RS25030	COG1175	transmembrane transport
FYC74_RS25040	COG1940	carbohydrate kinase activity
FYC74_RS25045	COG0668	transmembrane transport
FYC74_RS25055	COG2264	protein methyltransferase activity
FYC74_RS25090	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FYC74_RS25095	COG3693	PFAM glycoside hydrolase, family 10
FYC74_RS25115	COG1846	Transcriptional regulator
FYC74_RS25150	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FYC74_RS25165	COG1113	amino acid transport
FYC74_RS25170	COG1268	BioY protein
FYC74_RS25175	COG1113	amino acid transport
FYC74_RS25190	COG4552	Acetyltransferase involved in intracellular survival and related
FYC74_RS25205	COG3594	Acyltransferase
FYC74_RS25225	COG0544	peptidyl-prolyl cis-trans isomerase activity
FYC74_RS25230	COG0740	serine-type endopeptidase activity
FYC74_RS25235	COG0740	serine-type endopeptidase activity
FYC74_RS25240	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FYC74_RS25250	COG0525	valine-tRNA ligase activity
FYC74_RS25255	COG0285	dihydrofolate synthase activity
FYC74_RS25265	COG0105	UTP biosynthetic process
FYC74_RS25270	COG1077	Cell shape determining protein MreB Mrl
FYC74_RS25285	COG0768	penicillin binding
FYC74_RS25290	COG0772	Belongs to the SEDS family
FYC74_RS25315	COG1530	ribonuclease E activity
FYC74_RS25320	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FYC74_RS25325	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FYC74_RS25330	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FYC74_RS25340	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FYC74_RS25345	COG0463	Glycosyl transferase, family 2
FYC74_RS25345	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FYC74_RS25350	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FYC74_RS25360	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FYC74_RS25370	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FYC74_RS25385	COG0501	Belongs to the peptidase M48B family
FYC74_RS25400	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FYC74_RS25410	COG0799	negative regulation of ribosome biogenesis
FYC74_RS25415	COG0588	phosphoglycerate mutase activity
FYC74_RS25435	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FYC74_RS25445	COG0495	leucyl-tRNA aminoacylation
FYC74_RS25455	COG1307	EDD domain protein, DegV family
FYC74_RS25460	COG1555	photosystem II stabilization
FYC74_RS25465	COG1234	tRNA 3'-trailer cleavage
FYC74_RS25470	COG1309	transcriptional regulator
FYC74_RS25480	COG2353	YceI-like domain
FYC74_RS25500	COG0268	Binds directly to 16S ribosomal RNA
FYC74_RS25505	COG0481	GTPase activity
FYC74_RS25535	COG1420	regulation of RNA biosynthetic process
FYC74_RS25540	COG0484	heat shock protein binding
FYC74_RS25545	COG2070	2-Nitropropane dioxygenase
FYC74_RS25560	COG4946	Tricorn protease homolog
FYC74_RS25560	COG0793	Belongs to the peptidase S41A family
FYC74_RS25565	COG0537	adenosine 5'-monophosphoramidase activity
FYC74_RS25570	COG1234	tRNA 3'-trailer cleavage
FYC74_RS25575	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FYC74_RS25580	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FYC74_RS25610	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FYC74_RS25620	COG2315	Protein conserved in bacteria
FYC74_RS25630	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FYC74_RS25655	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FYC74_RS25700	COG2814	Major facilitator Superfamily
FYC74_RS25705	COG3119	arylsulfatase activity
FYC74_RS25715	COG1609	Transcriptional regulator
FYC74_RS25740	COG1381	Involved in DNA repair and RecF pathway recombination
FYC74_RS25745	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FYC74_RS25755	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FYC74_RS25760	COG1120	ATPase activity
FYC74_RS25765	COG0803	Belongs to the bacterial solute-binding protein 9 family
FYC74_RS25765	COG3443	Belongs to the bacterial solute-binding protein 9 family
FYC74_RS25770	COG0423	glycine-tRNA ligase activity
FYC74_RS25805	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FYC74_RS25805	COG0574	Belongs to the PEP-utilizing enzyme family
FYC74_RS25825	COG2146	nitrite reductase [NAD(P)H] activity
FYC74_RS25825	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FYC74_RS25865	COG0583	DNA-binding transcription factor activity
FYC74_RS25870	COG0243	molybdopterin cofactor binding
FYC74_RS25875	COG2949	membrane
FYC74_RS25885	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FYC74_RS25895	COG0358	DNA primase activity
FYC74_RS25900	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FYC74_RS25915	COG1070	Carbohydrate kinase
FYC74_RS25965	COG0464	growth
FYC74_RS25975	COG1674	ftsk spoiiie
FYC74_RS26060	COG1077	Cell shape determining protein MreB Mrl
FYC74_RS26070	COG2255	four-way junction helicase activity
FYC74_RS26085	COG0825	malonyl-CoA metabolic process
FYC74_RS26085	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FYC74_RS26090	COG0318	PFAM AMP-dependent synthetase and ligase
FYC74_RS26100	COG2186	Transcriptional regulator
FYC74_RS26110	COG1414	Transcriptional regulator
FYC74_RS26115	COG3386	PFAM SMP-30 Gluconolaconase
FYC74_RS26145	COG1175	transmembrane transport
FYC74_RS26150	COG0395	ABC-type sugar transport system, permease component
FYC74_RS26175	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FYC74_RS26180	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FYC74_RS26190	COG4214	carbohydrate transport
FYC74_RS26195	COG1129	ABC transporter
FYC74_RS26230	COG2226	methyltransferase
FYC74_RS26240	COG0477	Major facilitator Superfamily
FYC74_RS26250	COG2130	NADP-dependent
FYC74_RS26255	COG1764	response to oxidative stress
FYC74_RS26285	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FYC74_RS26290	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FYC74_RS26295	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FYC74_RS26325	COG0789	Transcriptional regulator
FYC74_RS26340	COG1309	transcriptional regulator
FYC74_RS26345	COG0477	Major facilitator Superfamily
FYC74_RS26355	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FYC74_RS26400	COG1358	cellular component organization or biogenesis
FYC74_RS26410	COG0586	Pfam SNARE associated Golgi protein
FYC74_RS26470	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FYC74_RS26545	COG2318	DinB family
FYC74_RS26580	COG3845	ABC transporter
FYC74_RS26605	COG0438	transferase activity, transferring glycosyl groups
FYC74_RS26630	COG0860	N-Acetylmuramoyl-L-alanine amidase
FYC74_RS26640	COG0477	Major facilitator Superfamily
FYC74_RS26650	COG2197	response regulator
FYC74_RS26655	COG4585	Histidine kinase
FYC74_RS26660	COG2030	dehydratase
FYC74_RS26675	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FYC74_RS26690	COG0800	Aldolase
FYC74_RS26695	COG3022	response to hydroperoxide
FYC74_RS26720	COG0583	DNA-binding transcription factor activity
FYC74_RS26745	COG0586	Pfam SNARE associated Golgi protein
FYC74_RS26750	COG4585	Histidine kinase
FYC74_RS26755	COG2197	response regulator
FYC74_RS26770	COG0431	NADPH-dependent FMN reductase
FYC74_RS26780	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FYC74_RS26785	COG2815	serine threonine protein kinase
FYC74_RS26785	COG0515	serine threonine protein kinase
FYC74_RS26855	COG2814	Major facilitator Superfamily
FYC74_RS26860	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FYC74_RS26870	COG2197	response regulator
FYC74_RS26900	COG1120	ATPase activity
FYC74_RS26905	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FYC74_RS26960	COG1994	Peptidase M50
FYC74_RS26980	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FYC74_RS26990	COG2814	Major facilitator Superfamily
FYC74_RS27025	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FYC74_RS27035	COG0174	glutamine synthetase
FYC74_RS27050	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FYC74_RS27050	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FYC74_RS27060	COG4115	mRNA cleavage
FYC74_RS27065	COG2161	toxin-antitoxin pair type II binding
FYC74_RS27070	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FYC74_RS27080	COG1609	Transcriptional regulator
FYC74_RS27085	COG1653	transport
FYC74_RS27090	COG1175	transmembrane transport
FYC74_RS27095	COG3833	ABC-type maltose transport systems, permease component
FYC74_RS27100	COG0366	Alpha amylase catalytic
FYC74_RS27120	COG1309	transcriptional regulator
FYC74_RS27145	COG2197	response regulator
FYC74_RS27155	COG0745	RESPONSE REGULATOR receiver
FYC74_RS27185	COG0501	Belongs to the peptidase M48B family
FYC74_RS27190	COG1733	regulation of RNA biosynthetic process
FYC74_RS27195	COG0702	epimerase
FYC74_RS27205	COG0174	glutamine synthetase
FYC74_RS27225	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FYC74_RS27230	COG0321	lipoyl(octanoyl) transferase activity
FYC74_RS27275	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FYC74_RS27285	COG0508	dehydrogenase complex catalyzes the overall conversion of
FYC74_RS27290	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FYC74_RS27295	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FYC74_RS27305	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FYC74_RS27310	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FYC74_RS27330	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FYC74_RS27335	COG2226	methyltransferase
FYC74_RS27355	COG4585	Histidine kinase
FYC74_RS27360	COG2197	response regulator
FYC74_RS27365	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FYC74_RS27370	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FYC74_RS27410	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FYC74_RS27420	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FYC74_RS27425	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FYC74_RS27435	COG1376	ErfK ybiS ycfS ynhG family protein
FYC74_RS27445	COG1845	cytochrome c oxidase, subunit III
FYC74_RS27450	COG2010	Cytochrome c
FYC74_RS27455	COG0723	plastoquinol--plastocyanin reductase activity
FYC74_RS27460	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FYC74_RS27465	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FYC74_RS27470	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FYC74_RS27520	COG0438	transferase activity, transferring glycosyl groups
FYC74_RS27540	COG0003	Pfam Anion-transporting ATPase
FYC74_RS27550	COG1940	carbohydrate kinase activity
FYC74_RS27580	COG2197	response regulator
FYC74_RS27585	COG0205	6-phosphofructokinase activity
FYC74_RS27590	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FYC74_RS27605	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FYC74_RS27615	COG2193	ferroxidase activity
FYC74_RS27620	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FYC74_RS27625	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FYC74_RS27630	COG2815	serine threonine protein kinase
FYC74_RS27630	COG0515	serine threonine protein kinase
FYC74_RS27635	COG2022	thiamine diphosphate biosynthetic process
FYC74_RS27645	COG2022	thiamine diphosphate biosynthetic process
FYC74_RS27645	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FYC74_RS27650	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FYC74_RS27660	COG0352	thiamine-phosphate diphosphorylase activity
FYC74_RS27675	COG1233	COG1233 Phytoene dehydrogenase and related
FYC74_RS27680	COG1309	transcriptional regulator
FYC74_RS27710	COG0714	Associated with various cellular activities
FYC74_RS27720	COG0275	rRNA processing
FYC74_RS27730	COG0768	penicillin binding
FYC74_RS27735	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FYC74_RS27745	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FYC74_RS27750	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FYC74_RS27760	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FYC74_RS27765	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FYC74_RS27770	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FYC74_RS27775	COG1496	oxidoreductase activity
FYC74_RS27780	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FYC74_RS27785	COG1799	cell septum assembly
FYC74_RS27795	COG3599	regulation of cell shape
FYC74_RS27800	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FYC74_RS27810	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FYC74_RS27825	COG0025	NhaP-type Na H and K H
FYC74_RS27855	COG0587	DNA-directed DNA polymerase activity
FYC74_RS27865	COG1432	Conserved Protein
FYC74_RS27885	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FYC74_RS27905	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FYC74_RS27910	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FYC74_RS27915	COG0131	Imidazoleglycerol-phosphate dehydratase
FYC74_RS27925	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FYC74_RS27930	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FYC74_RS27935	COG0251	oxidation-reduction process
FYC74_RS27940	COG0107	imidazoleglycerol-phosphate synthase activity
FYC74_RS27955	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FYC74_RS27980	COG0134	indole-3-glycerol-phosphate synthase activity
FYC74_RS27985	COG0133	tryptophan synthase activity
FYC74_RS27990	COG0159	tryptophan synthase activity
FYC74_RS28000	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FYC74_RS28005	COG2301	Belongs to the HpcH HpaI aldolase family
FYC74_RS28010	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYC74_RS28030	COG1397	ADP-ribosylglycohydrolase
FYC74_RS28040	COG0067	glutamate synthase
FYC74_RS28040	COG0070	glutamate synthase
FYC74_RS28040	COG0069	glutamate synthase activity
FYC74_RS28060	COG2304	oxidoreductase activity
FYC74_RS28075	COG0287	Prephenate dehydrogenase
FYC74_RS28075	COG1605	Chorismate mutase
FYC74_RS28095	COG0737	Belongs to the 5'-nucleotidase family
FYC74_RS28140	COG2050	protein possibly involved in aromatic compounds catabolism
FYC74_RS28165	COG1643	Atp-dependent helicase
FYC74_RS28185	COG0237	dephospho-CoA kinase activity
FYC74_RS28195	COG2226	methyltransferase
FYC74_RS28210	COG2267	carboxylic ester hydrolase activity
FYC74_RS28220	COG0667	Aldo Keto reductase
FYC74_RS28245	COG0402	S-adenosylhomocysteine deaminase activity
FYC74_RS28290	COG2226	methyltransferase
FYC74_RS28295	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FYC74_RS28300	COG2313	pseudouridylate synthase activity
FYC74_RS28310	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FYC74_RS28315	COG0584	glycerophosphoryl diester phosphodiesterase
FYC74_RS28325	COG0556	nucleotide-excision repair
FYC74_RS28345	COG0387	Pfam Sodium calcium exchanger
FYC74_RS28350	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FYC74_RS28365	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FYC74_RS28390	COG0322	excinuclease ABC activity
FYC74_RS28395	COG1660	Displays ATPase and GTPase activities
FYC74_RS28400	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FYC74_RS28405	COG1481	regulation of sporulation
FYC74_RS28410	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FYC74_RS28415	COG0126	phosphoglycerate kinase activity
FYC74_RS28420	COG0149	triose-phosphate isomerase activity
FYC74_RS28425	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FYC74_RS28435	COG0166	Belongs to the GPI family
FYC74_RS28440	COG0363	glucosamine-6-phosphate deaminase activity
FYC74_RS28455	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FYC74_RS28465	COG0109	protoheme IX farnesyltransferase activity
FYC74_RS28495	COG1131	(ABC) transporter
FYC74_RS28500	COG2746	aminoglycoside 3-N-acetyltransferase activity
FYC74_RS28515	COG0719	Fe-S assembly protein
FYC74_RS28525	COG0396	ATPase activity
FYC74_RS28530	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FYC74_RS28535	COG0822	iron-sulfur transferase activity
FYC74_RS28540	COG2151	metal-sulfur cluster biosynthetic enzyme
FYC74_RS28545	COG2076	Multidrug Resistance protein
FYC74_RS28550	COG3226	Transcriptional regulator
FYC74_RS28555	COG2171	N-acyltransferase activity
FYC74_RS28590	COG2205	protein histidine kinase activity
FYC74_RS28595	COG0745	RESPONSE REGULATOR receiver
FYC74_RS28615	COG1309	transcriptional regulator
FYC74_RS28625	COG1063	alcohol dehydrogenase
FYC74_RS28645	COG1349	DNA-binding transcription factor activity
FYC74_RS28650	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FYC74_RS28655	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FYC74_RS28670	COG1802	Transcriptional regulator
FYC74_RS28675	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FYC74_RS28685	COG1175	transmembrane transport
FYC74_RS28690	COG0395	ABC-type sugar transport system, permease component
FYC74_RS28715	COG3866	Pectate lyase
FYC74_RS28720	COG4677	pectinesterase activity
FYC74_RS28730	COG0768	penicillin binding
FYC74_RS28740	COG1414	Transcriptional regulator
FYC74_RS28765	COG5285	phytanoyl-CoA dioxygenase
FYC74_RS28770	COG1917	Cupin 2, conserved barrel domain protein
FYC74_RS28775	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FYC74_RS28780	COG0456	acetyltransferase
FYC74_RS28815	COG1797	cobyrinic acid a,c-diamide synthase activity
FYC74_RS28830	COG1492	cobalamin metabolic process
FYC74_RS28850	COG0235	Class ii aldolase
FYC74_RS28865	COG0488	(ABC) transporter
FYC74_RS28875	COG1024	Enoyl-CoA hydratase
FYC74_RS28905	COG1028	Short-chain dehydrogenase reductase Sdr
FYC74_RS28910	COG3387	PFAM Glycoside hydrolase 15-related
FYC74_RS28935	COG1404	Belongs to the peptidase S8 family
FYC74_RS28945	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FYC74_RS28950	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FYC74_RS28970	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FYC74_RS29000	COG1028	Short-chain dehydrogenase reductase Sdr
FYC74_RS29010	COG2186	Transcriptional regulator
FYC74_RS29015	COG2807	transmembrane transport
FYC74_RS29025	COG0588	phosphoglycerate mutase activity
FYC74_RS29030	COG0560	Phosphoserine phosphatase
FYC74_RS29030	COG3830	Belongs to the UPF0237 family
FYC74_RS29035	COG1131	(ABC) transporter
FYC74_RS29035	COG0842	Transport permease protein
FYC74_RS29035	COG1716	ATPase activity
FYC74_RS29045	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FYC74_RS29050	COG4221	oxidoreductase activity
FYC74_RS29060	COG2197	response regulator
FYC74_RS29075	COG1119	ATPase activity
FYC74_RS29095	COG1881	PFAM PEBP family protein
FYC74_RS29105	COG2094	Belongs to the DNA glycosylase MPG family
FYC74_RS29140	COG0647	UMP catabolic process
FYC74_RS29145	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FYC74_RS29150	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FYC74_RS29155	COG1120	ATPase activity
FYC74_RS29175	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FYC74_RS29180	COG0497	DNA recombination
FYC74_RS29195	COG3387	PFAM Glycoside hydrolase 15-related
FYC74_RS29200	COG0504	CTP synthase activity
FYC74_RS29205	COG0494	nUDIX hydrolase
FYC74_RS29215	COG0686	Belongs to the AlaDH PNT family
FYC74_RS29230	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FYC74_RS29235	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FYC74_RS29240	COG1187	pseudouridine synthase activity
FYC74_RS29245	COG0494	nUDIX hydrolase
FYC74_RS29265	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FYC74_RS29275	COG1160	GTP binding
FYC74_RS29300	COG0671	phosphoesterase, PA-phosphatase related
FYC74_RS29310	COG0477	Major facilitator Superfamily
FYC74_RS29320	COG1799	cell septum assembly
FYC74_RS29335	COG0765	amino acid transport
FYC74_RS29355	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FYC74_RS29380	COG0587	DNA-directed DNA polymerase activity
FYC74_RS29395	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FYC74_RS29395	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FYC74_RS29410	COG1725	Transcriptional regulator
FYC74_RS29435	COG2755	lipolytic protein G-D-S-L family
FYC74_RS29465	COG2188	Transcriptional regulator
FYC74_RS29470	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FYC74_RS29480	COG1309	transcriptional regulator
FYC74_RS29485	COG0243	molybdopterin cofactor binding
FYC74_RS29490	COG2851	Citrate transporter
FYC74_RS29515	COG0640	Transcriptional regulator
FYC74_RS29525	COG1960	acyl-CoA dehydrogenase activity
FYC74_RS29545	COG0789	Transcriptional regulator
FYC74_RS29560	COG3876	Protein conserved in bacteria
FYC74_RS29570	COG0318	PFAM AMP-dependent synthetase and ligase
FYC74_RS29595	COG2149	membrane
FYC74_RS29600	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FYC74_RS29620	COG1063	alcohol dehydrogenase
FYC74_RS29625	COG1028	Short-chain dehydrogenase reductase Sdr
FYC74_RS29635	COG3265	gluconokinase activity
FYC74_RS29640	COG2186	Transcriptional regulator
FYC74_RS29645	COG3012	SEC-C Motif Domain Protein
FYC74_RS29685	COG0667	Aldo Keto reductase
FYC74_RS29690	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FYC74_RS29700	COG0598	Magnesium transport protein CorA
FYC74_RS29705	COG0588	phosphoglycerate mutase activity
FYC74_RS29720	COG0215	cysteine-tRNA ligase activity
FYC74_RS29730	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FYC74_RS29735	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FYC74_RS29740	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FYC74_RS29745	COG1414	Transcriptional regulator
FYC74_RS29750	COG1410	methionine synthase
FYC74_RS29750	COG0646	methionine synthase
FYC74_RS29760	COG4166	transmembrane transport
FYC74_RS29765	COG2197	response regulator
FYC74_RS29775	COG1994	Peptidase M50
FYC74_RS29775	COG0517	IMP dehydrogenase activity
FYC74_RS29795	COG1222	aaa ATPase
FYC74_RS29800	COG4122	O-methyltransferase activity
FYC74_RS29815	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
FYC74_RS29820	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
FYC74_RS29825	COG1609	Transcriptional regulator
FYC74_RS29835	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
FYC74_RS29840	COG0545	Peptidyl-prolyl cis-trans isomerase
FYC74_RS29870	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FYC74_RS29875	COG0805	protein transport
FYC74_RS29910	COG0564	pseudouridine synthase activity
FYC74_RS29925	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FYC74_RS29930	COG4175	Glycine betaine
FYC74_RS29930	COG0517	IMP dehydrogenase activity
FYC74_RS29935	COG4176	ABC-type proline glycine betaine transport system permease component
FYC74_RS29960	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FYC74_RS29965	COG2188	Transcriptional regulator
FYC74_RS29970	COG0174	glutamine synthetase
FYC74_RS29975	COG1012	belongs to the aldehyde dehydrogenase family
FYC74_RS30020	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FYC74_RS30025	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FYC74_RS30030	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FYC74_RS30035	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FYC74_RS30040	COG5002	protein histidine kinase activity
FYC74_RS30045	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FYC74_RS30050	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FYC74_RS30050	COG0072	phenylalanine-tRNA ligase activity
FYC74_RS30060	COG1051	belongs to the nudix hydrolase family
FYC74_RS30080	COG1649	PFAM Uncharacterised BCR, COG1649
FYC74_RS30090	COG0697	spore germination
FYC74_RS30110	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FYC74_RS30115	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FYC74_RS30120	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FYC74_RS30125	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FYC74_RS30130	COG1438	arginine binding
FYC74_RS30160	COG0165	Argininosuccinate lyase
FYC74_RS30175	COG0477	Major facilitator Superfamily
FYC74_RS30180	COG0204	Acyl-transferase
FYC74_RS30180	COG0318	PFAM AMP-dependent synthetase and ligase
FYC74_RS30185	COG0584	glycerophosphoryl diester phosphodiesterase
FYC74_RS30215	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FYC74_RS30220	COG2011	ABC-type metal ion transport system permease component
FYC74_RS30225	COG1464	Belongs to the NlpA lipoprotein family
FYC74_RS30240	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FYC74_RS30245	COG1648	precorrin-2 dehydrogenase activity
FYC74_RS30245	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FYC74_RS30250	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FYC74_RS30300	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FYC74_RS30355	COG1175	transmembrane transport
FYC74_RS30360	COG0395	ABC-type sugar transport system, permease component
FYC74_RS30380	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FYC74_RS30385	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FYC74_RS30405	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FYC74_RS30410	COG1560	Kdo2-lipid A biosynthetic process
FYC74_RS30415	COG0438	transferase activity, transferring glycosyl groups
FYC74_RS30430	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
FYC74_RS30435	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
FYC74_RS30440	COG0217	transcriptional regulatory protein
FYC74_RS30445	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FYC74_RS30450	COG0632	four-way junction helicase activity
FYC74_RS30455	COG2255	four-way junction helicase activity
FYC74_RS30465	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FYC74_RS30470	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FYC74_RS30475	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FYC74_RS30480	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FYC74_RS30485	COG1196	nuclear chromosome segregation
FYC74_RS30490	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FYC74_RS30500	COG0124	histidyl-tRNA synthetase
FYC74_RS30515	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FYC74_RS30535	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FYC74_RS30540	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FYC74_RS30550	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FYC74_RS30555	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FYC74_RS30560	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FYC74_RS30565	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FYC74_RS30575	COG0006	proline dipeptidase activity
FYC74_RS30580	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FYC74_RS30585	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FYC74_RS30595	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FYC74_RS30600	COG0540	Belongs to the ATCase OTCase family
FYC74_RS30605	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FYC74_RS30615	COG0505	Belongs to the CarA family
FYC74_RS30620	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FYC74_RS30625	COG0167	dihydroorotate dehydrogenase activity
FYC74_RS30630	COG0284	orotidine-5'-phosphate decarboxylase activity
FYC74_RS30640	COG0194	GDP metabolic process
FYC74_RS30645	COG1758	RNA polymerase activity
FYC74_RS30655	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FYC74_RS30670	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FYC74_RS30705	COG1653	transport
FYC74_RS30710	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FYC74_RS30715	COG2390	Transcriptional regulator
FYC74_RS30765	COG2233	PERMEase
FYC74_RS30780	COG2409	Drug exporters of the RND superfamily
FYC74_RS30785	COG2223	nitrite transmembrane transporter activity
FYC74_RS30805	COG1595	DNA-templated transcription, initiation
FYC74_RS30815	COG3201	nicotinamide mononucleotide transporter
FYC74_RS30820	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FYC74_RS30820	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FYC74_RS30825	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FYC74_RS30830	COG0140	phosphoribosyl-ATP diphosphatase activity
FYC74_RS30835	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FYC74_RS30885	COG1960	acyl-CoA dehydrogenase activity
FYC74_RS30920	COG2270	Major facilitator Superfamily
FYC74_RS30960	COG0438	transferase activity, transferring glycosyl groups
FYC74_RS30965	COG0438	transferase activity, transferring glycosyl groups
FYC74_RS31000	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FYC74_RS31015	COG1414	Transcriptional regulator
FYC74_RS31020	COG2146	nitrite reductase [NAD(P)H] activity
FYC74_RS31025	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FYC74_RS31040	COG2018	Roadblock/LC7 domain
FYC74_RS31055	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
FYC74_RS31070	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FYC74_RS31080	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FYC74_RS31110	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FYC74_RS31130	COG1716	ATPase activity
FYC74_RS31150	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FYC74_RS31160	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FYC74_RS31160	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FYC74_RS31180	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FYC74_RS31185	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FYC74_RS31190	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FYC74_RS31215	COG0384	phenazine biosynthesis protein PhzF
FYC74_RS31255	COG0723	plastoquinol--plastocyanin reductase activity
FYC74_RS31260	COG2175	clavaminate synthase activity
FYC74_RS31265	COG3321	synthase
FYC74_RS31265	COG1028	Short-chain dehydrogenase reductase Sdr
FYC74_RS31265	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FYC74_RS31265	COG0318	PFAM AMP-dependent synthetase and ligase
FYC74_RS31265	COG0300	oxidoreductase activity
FYC74_RS31280	COG0477	Major facilitator Superfamily
FYC74_RS31320	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FYC74_RS31335	COG2318	DinB family
FYC74_RS31345	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FYC74_RS31350	COG1028	Short-chain dehydrogenase reductase Sdr
FYC74_RS31360	COG1968	undecaprenyl-diphosphatase activity
FYC74_RS31375	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FYC74_RS31430	COG1739	Uncharacterized protein family UPF0029
FYC74_RS31465	COG2208	phosphoserine phosphatase activity
FYC74_RS31465	COG2770	Histidine kinase
FYC74_RS31470	COG0596	Alpha beta hydrolase
FYC74_RS31475	COG0420	3'-5' exonuclease activity
FYC74_RS31480	COG0419	ATPase involved in DNA repair
FYC74_RS31490	COG1028	Short-chain dehydrogenase reductase Sdr
FYC74_RS31555	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FYC74_RS31560	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FYC74_RS31600	COG1595	DNA-templated transcription, initiation
FYC74_RS31605	COG2188	Transcriptional regulator
FYC74_RS31610	COG1940	carbohydrate kinase activity
FYC74_RS31615	COG2197	response regulator
FYC74_RS31620	COG4585	Histidine kinase
FYC74_RS31640	COG3663	DNA glycosylase
FYC74_RS31645	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FYC74_RS31665	COG0456	acetyltransferase
FYC74_RS31680	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FYC74_RS31685	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FYC74_RS31690	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FYC74_RS31725	COG0740	serine-type endopeptidase activity
FYC74_RS31760	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FYC74_RS31765	COG1834	amidinotransferase
FYC74_RS31770	COG1522	sequence-specific DNA binding
FYC74_RS31775	COG3279	Response regulator of the LytR AlgR family
FYC74_RS31790	COG3275	phosphorelay sensor kinase activity
FYC74_RS31805	COG0205	6-phosphofructokinase activity
FYC74_RS31810	COG3442	glutamine amidotransferase
FYC74_RS31815	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FYC74_RS31820	COG0242	peptide deformylase activity
FYC74_RS31830	COG1960	acyl-CoA dehydrogenase activity
FYC74_RS31840	COG2124	cytochrome p450
FYC74_RS31845	COG3424	synthase
FYC74_RS31855	COG1012	belongs to the aldehyde dehydrogenase family
FYC74_RS31865	COG1793	dna ligase
FYC74_RS31875	COG1396	sequence-specific DNA binding
FYC74_RS31875	COG3800	Transcriptional regulator
FYC74_RS31885	COG1960	acyl-CoA dehydrogenase activity
FYC74_RS31890	COG1960	acyl-CoA dehydrogenase activity
FYC74_RS31945	COG0129	dihydroxy-acid dehydratase activity
FYC74_RS31950	COG1472	Belongs to the glycosyl hydrolase 3 family
FYC74_RS31960	COG1175	transmembrane transport
FYC74_RS31970	COG1609	Transcriptional regulator
FYC74_RS31985	COG0531	amino acid
FYC74_RS31995	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FYC74_RS32005	COG1012	belongs to the aldehyde dehydrogenase family
FYC74_RS32045	COG1396	sequence-specific DNA binding
FYC74_RS32045	COG3800	Transcriptional regulator
FYC74_RS32050	COG2079	MmgE PrpD family protein
FYC74_RS32055	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FYC74_RS32105	COG0395	ABC-type sugar transport system, permease component
FYC74_RS32110	COG1175	transmembrane transport
FYC74_RS32130	COG2188	Transcriptional regulator
FYC74_RS32170	COG1012	belongs to the aldehyde dehydrogenase family
FYC74_RS32185	COG1940	carbohydrate kinase activity
FYC74_RS32185	COG1846	Transcriptional regulator
FYC74_RS32190	COG1070	Carbohydrate kinase
FYC74_RS32195	COG2115	Belongs to the xylose isomerase family
FYC74_RS32205	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FYC74_RS32240	COG2018	Roadblock/LC7 domain
FYC74_RS32250	COG1946	Acyl-CoA thioesterase
FYC74_RS32265	COG0254	rRNA binding
FYC74_RS32275	COG1132	(ABC) transporter
FYC74_RS32295	COG1132	(ABC) transporter
FYC74_RS32305	COG2072	flavoprotein involved in K transport
FYC74_RS32310	COG0432	Pfam Uncharacterised protein family UPF0047
FYC74_RS32335	COG3290	protein histidine kinase activity
FYC74_RS32340	COG4565	transcriptional regulatory protein
FYC74_RS32350	COG2080	2 iron, 2 sulfur cluster binding
FYC74_RS32355	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FYC74_RS32360	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FYC74_RS32370	COG3387	PFAM Glycoside hydrolase 15-related
FYC74_RS32375	COG0726	polysaccharide deacetylase
FYC74_RS32385	COG4221	oxidoreductase activity
FYC74_RS32415	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FYC74_RS32440	COG2971	BadF BadG BcrA BcrD
FYC74_RS32445	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FYC74_RS32450	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FYC74_RS32470	COG0601	transmembrane transport
FYC74_RS32485	COG1960	acyl-CoA dehydrogenase activity
FYC74_RS32520	COG0671	phosphoesterase, PA-phosphatase related
FYC74_RS32575	COG1053	succinate dehydrogenase
FYC74_RS32585	COG1028	Short-chain dehydrogenase reductase Sdr
FYC74_RS32615	COG0584	glycerophosphoryl diester phosphodiesterase
FYC74_RS32655	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FYC74_RS32685	COG1660	Displays ATPase and GTPase activities
FYC74_RS32695	COG0445	tRNA wobble uridine modification
FYC74_RS32700	COG4585	Histidine kinase
FYC74_RS32705	COG2197	response regulator
FYC74_RS32720	COG2723	6-phospho-beta-galactosidase activity
FYC74_RS32725	COG0395	ABC-type sugar transport system, permease component
FYC74_RS32730	COG1175	transmembrane transport
FYC74_RS32740	COG1501	Belongs to the glycosyl hydrolase 31 family
FYC74_RS32755	COG0783	Belongs to the Dps family
FYC74_RS32770	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FYC74_RS32775	COG0191	fructose-bisphosphate aldolase activity
FYC74_RS32780	COG2813	Specifically methylates the guanine in position
FYC74_RS32790	COG1940	carbohydrate kinase activity
FYC74_RS32825	COG1349	DNA-binding transcription factor activity
FYC74_RS32860	COG0463	Glycosyl transferase, family 2
FYC74_RS32865	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FYC74_RS32890	COG1653	transport
FYC74_RS32895	COG1175	transmembrane transport
FYC74_RS32905	COG1472	Belongs to the glycosyl hydrolase 3 family
FYC74_RS32915	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FYC74_RS32925	COG0137	argininosuccinate synthase activity
FYC74_RS32950	COG1846	Transcriptional regulator
FYC74_RS32955	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FYC74_RS32960	COG1993	acr, cog1993
FYC74_RS32965	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FYC74_RS32970	COG1968	undecaprenyl-diphosphatase activity
FYC74_RS32985	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FYC74_RS33000	COG2226	methyltransferase
FYC74_RS33005	COG2188	Transcriptional regulator
FYC74_RS33010	COG3458	cephalosporin-C deacetylase activity
FYC74_RS33025	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FYC74_RS33045	COG0446	pyridine nucleotide-disulphide oxidoreductase
FYC74_RS33045	COG1902	pentaerythritol trinitrate reductase activity
FYC74_RS33075	COG1461	Dihydroxyacetone kinase
FYC74_RS33080	COG2376	Dihydroxyacetone kinase
FYC74_RS33095	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FYC74_RS33100	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FYC74_RS33120	COG1216	Glycosyl transferase, family 2
FYC74_RS33135	COG2223	nitrite transmembrane transporter activity
FYC74_RS33155	COG0601	transmembrane transport
FYC74_RS33165	COG1124	(ABC) transporter
FYC74_RS33170	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FYC74_RS33185	COG0395	ABC-type sugar transport system, permease component
FYC74_RS33190	COG1175	transmembrane transport
FYC74_RS33200	COG1940	carbohydrate kinase activity
FYC74_RS33215	COG2072	flavoprotein involved in K transport
FYC74_RS33220	COG1028	Short-chain dehydrogenase reductase Sdr
FYC74_RS33245	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYC74_RS33265	COG1609	Transcriptional regulator
FYC74_RS33275	COG4948	Mandelate Racemase Muconate Lactonizing
FYC74_RS33290	COG1028	Short-chain dehydrogenase reductase Sdr
FYC74_RS33330	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FYC74_RS33340	COG0179	Fumarylacetoacetate (FAA) hydrolase
FYC74_RS33350	COG4948	Mandelate Racemase Muconate Lactonizing
FYC74_RS33355	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FYC74_RS33365	COG1802	Transcriptional regulator
FYC74_RS33390	COG4677	pectinesterase activity
FYC74_RS33405	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FYC74_RS33410	COG0747	negative chemotaxis
FYC74_RS33415	COG0601	transmembrane transport
FYC74_RS33420	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FYC74_RS33425	COG0444	Belongs to the ABC transporter superfamily
FYC74_RS33430	COG4608	Belongs to the ABC transporter superfamily
FYC74_RS33475	COG3250	beta-galactosidase activity
FYC74_RS33480	COG0667	Aldo Keto reductase
FYC74_RS33485	COG3395	kinase activity
FYC74_RS33490	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FYC74_RS33510	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FYC74_RS33520	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FYC74_RS33560	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FYC74_RS33565	COG0318	PFAM AMP-dependent synthetase and ligase
FYC74_RS33605	COG0673	inositol 2-dehydrogenase activity
FYC74_RS33640	COG0346	lactoylglutathione lyase activity
FYC74_RS33645	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FYC74_RS33655	COG0583	DNA-binding transcription factor activity
FYC74_RS33690	COG1191	sigma factor activity
FYC74_RS33700	COG0740	serine-type endopeptidase activity
FYC74_RS33705	COG0740	serine-type endopeptidase activity
FYC74_RS33715	COG0328	RNA-DNA hybrid ribonuclease activity
FYC74_RS33725	COG0667	Aldo Keto reductase
FYC74_RS33745	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FYC74_RS33750	COG0515	serine threonine protein kinase
FYC74_RS33750	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FYC74_RS33755	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FYC74_RS33765	COG2340	Cysteine-rich secretory protein family
FYC74_RS33800	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FYC74_RS33820	COG3189	MarR family transcriptional regulator
FYC74_RS33840	COG0477	Major facilitator Superfamily
FYC74_RS33850	COG1982	Orn Lys Arg decarboxylase major
FYC74_RS33890	COG1252	NADH dehydrogenase
FYC74_RS33905	COG2172	sigma factor antagonist activity
FYC74_RS33910	COG1366	Belongs to the anti-sigma-factor antagonist family
FYC74_RS33915	COG1366	Belongs to the anti-sigma-factor antagonist family
FYC74_RS33930	COG5002	protein histidine kinase activity
FYC74_RS33930	COG2205	protein histidine kinase activity
FYC74_RS33930	COG0784	Response regulator, receiver
FYC74_RS33960	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
FYC74_RS33965	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FYC74_RS33975	COG0366	Alpha amylase catalytic
FYC74_RS34020	COG0181	hydroxymethylbilane synthase activity
FYC74_RS34030	COG3285	dna ligase
FYC74_RS34030	COG1793	dna ligase
FYC74_RS34045	COG1535	isochorismatase
FYC74_RS34045	COG3433	isochorismatase activity
FYC74_RS34055	COG1169	isochorismate synthase
FYC74_RS34060	COG2382	esterase
FYC74_RS34090	COG0656	L-ascorbic acid biosynthetic process
FYC74_RS34110	COG0009	L-threonylcarbamoyladenylate synthase
FYC74_RS34130	COG0753	catalase activity
FYC74_RS34155	COG1088	dTDP-glucose 4,6-dehydratase activity
FYC74_RS34170	COG0243	molybdopterin cofactor binding
FYC74_RS34205	COG2124	cytochrome p450
FYC74_RS34210	COG0142	geranyltranstransferase activity
FYC74_RS34215	COG0475	glutathione-regulated potassium exporter activity
FYC74_RS34250	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
FYC74_RS34290	COG1073	alpha beta
FYC74_RS34305	COG1120	ATPase activity
FYC74_RS34315	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FYC74_RS34320	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FYC74_RS34330	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FYC74_RS34365	COG4209	transmembrane transport
FYC74_RS34370	COG1609	Transcriptional regulator
FYC74_RS34375	COG0028	Belongs to the TPP enzyme family
FYC74_RS34380	COG1028	Short-chain dehydrogenase reductase Sdr
FYC74_RS34410	COG2814	Major facilitator Superfamily
FYC74_RS34415	COG2197	response regulator
FYC74_RS34420	COG4585	Histidine kinase
FYC74_RS34430	COG1136	(ABC) transporter
FYC74_RS34430	COG0577	efflux transmembrane transporter activity
FYC74_RS34440	COG1959	2 iron, 2 sulfur cluster binding
FYC74_RS34445	COG1017	nitric oxide dioxygenase activity
FYC74_RS34445	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FYC74_RS34460	COG5640	endopeptidase activity
FYC74_RS34465	COG0583	DNA-binding transcription factor activity
FYC74_RS34475	COG2814	Major facilitator Superfamily
FYC74_RS34490	COG0583	DNA-binding transcription factor activity
FYC74_RS34550	COG1335	isochorismatase
FYC74_RS34560	COG2188	Transcriptional regulator
FYC74_RS34565	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FYC74_RS34580	COG1119	ATPase activity
FYC74_RS34635	COG2050	protein possibly involved in aromatic compounds catabolism
FYC74_RS34640	COG3396	Phenylacetate-CoA oxygenase
FYC74_RS34645	COG3460	Phenylacetate-CoA oxygenase
FYC74_RS34650	COG3396	Phenylacetate-CoA oxygenase
FYC74_RS34655	COG2151	metal-sulfur cluster biosynthetic enzyme
FYC74_RS34660	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FYC74_RS34705	COG1953	Uracil, thiamine, allantoin
FYC74_RS34710	COG3940	Belongs to the glycosyl hydrolase 43 family
FYC74_RS34715	COG1609	Transcriptional regulator
FYC74_RS34725	COG1175	transmembrane transport
FYC74_RS34730	COG0395	ABC-type sugar transport system, permease component
FYC74_RS34740	COG2175	clavaminate synthase activity
FYC74_RS34765	COG4977	sequence-specific DNA binding
FYC74_RS34775	COG2814	Major facilitator Superfamily
FYC74_RS34775	COG0477	Major facilitator Superfamily
FYC74_RS34785	COG2159	amidohydrolase
FYC74_RS34795	COG2205	protein histidine kinase activity
FYC74_RS34805	COG0326	Molecular chaperone. Has ATPase activity
FYC74_RS34815	COG2391	methyltransferase activity
FYC74_RS34820	COG3226	Transcriptional regulator
FYC74_RS34850	COG2755	lipolytic protein G-D-S-L family
FYC74_RS34850	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FYC74_RS34860	COG0745	RESPONSE REGULATOR receiver
FYC74_RS34865	COG2205	protein histidine kinase activity
FYC74_RS34875	COG2409	Drug exporters of the RND superfamily
FYC74_RS34880	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FYC74_RS34900	COG2239	Acts as a magnesium transporter
FYC74_RS34935	COG3119	arylsulfatase activity
FYC74_RS34940	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FYC74_RS34945	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FYC74_RS34950	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FYC74_RS34955	COG4948	Mandelate Racemase Muconate Lactonizing
FYC74_RS34960	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FYC74_RS34965	COG0747	negative chemotaxis
FYC74_RS34970	COG0601	transmembrane transport
FYC74_RS34975	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FYC74_RS34980	COG0444	Belongs to the ABC transporter superfamily
FYC74_RS34985	COG4608	Belongs to the ABC transporter superfamily
FYC74_RS35005	COG0604	alcohol dehydrogenase
FYC74_RS35015	COG0583	DNA-binding transcription factor activity
FYC74_RS35035	COG0494	nUDIX hydrolase
FYC74_RS35075	COG0714	Associated with various cellular activities
FYC74_RS35105	COG0431	NADPH-dependent FMN reductase
FYC74_RS35120	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FYC74_RS35130	COG0444	Belongs to the ABC transporter superfamily
FYC74_RS35135	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FYC74_RS35140	COG0601	transmembrane transport
FYC74_RS35180	COG1028	Short-chain dehydrogenase reductase Sdr
FYC74_RS35200	COG0765	amino acid transport
FYC74_RS35240	COG2936	dipeptidyl-peptidase activity
FYC74_RS35260	COG0235	Class ii aldolase
FYC74_RS35265	COG3395	kinase activity
FYC74_RS35280	COG1349	DNA-binding transcription factor activity
FYC74_RS35285	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FYC74_RS35290	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FYC74_RS35295	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FYC74_RS35300	COG1737	Transcriptional regulator
FYC74_RS35305	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FYC74_RS35305	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FYC74_RS35310	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FYC74_RS35355	COG0154	amidase activity
FYC74_RS35360	COG1309	transcriptional regulator
FYC74_RS35380	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
FYC74_RS35385	COG0739	heme binding
FYC74_RS35415	COG1028	Short-chain dehydrogenase reductase Sdr
FYC74_RS35430	COG1278	Cold shock
FYC74_RS35435	COG1309	transcriptional regulator
FYC74_RS35485	COG3408	Glycogen debranching enzyme
FYC74_RS35495	COG1028	Short-chain dehydrogenase reductase Sdr
FYC74_RS35500	COG0477	Major facilitator Superfamily
FYC74_RS35545	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYC74_RS35550	COG0583	DNA-binding transcription factor activity
FYC74_RS35570	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FYC74_RS35575	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FYC74_RS35580	COG1120	ATPase activity
FYC74_RS35595	COG2353	YceI-like domain
FYC74_RS35610	COG0367	asparagine synthase
FYC74_RS35635	COG0477	Major facilitator Superfamily
FYC74_RS35655	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FYC74_RS35690	COG0406	alpha-ribazole phosphatase activity
FYC74_RS35715	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FYC74_RS35745	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FYC74_RS35750	COG1120	ATPase activity
FYC74_RS35785	COG1609	Transcriptional regulator
FYC74_RS35795	COG1129	ABC transporter
FYC74_RS35800	COG1172	Belongs to the binding-protein-dependent transport system permease family
FYC74_RS35805	COG1172	Belongs to the binding-protein-dependent transport system permease family
FYC74_RS35815	COG3250	beta-galactosidase activity
FYC74_RS35820	COG0667	Aldo Keto reductase
FYC74_RS35825	COG4989	oxidoreductase activity
FYC74_RS35840	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FYC74_RS35845	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FYC74_RS35855	COG2814	Major facilitator Superfamily
FYC74_RS35870	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FYC74_RS35875	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FYC74_RS35890	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FYC74_RS35895	COG4257	antibiotic catabolic process
FYC74_RS35900	COG5640	endopeptidase activity
FYC74_RS35970	COG0604	alcohol dehydrogenase
FYC74_RS35970	COG3321	synthase
FYC74_RS35975	COG0604	alcohol dehydrogenase
FYC74_RS35975	COG3321	synthase
FYC74_RS35985	COG3321	synthase
FYC74_RS35985	COG0604	alcohol dehydrogenase
FYC74_RS35995	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FYC74_RS36015	COG2175	clavaminate synthase activity
FYC74_RS36025	COG1024	Enoyl-CoA hydratase
FYC74_RS36030	COG1024	Enoyl-CoA hydratase
FYC74_RS36050	COG2175	clavaminate synthase activity
FYC74_RS36060	COG0165	Argininosuccinate lyase
FYC74_RS36090	COG1309	transcriptional regulator
FYC74_RS36100	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FYC74_RS36125	COG0477	Major facilitator Superfamily
FYC74_RS36130	COG2124	cytochrome p450
FYC74_RS36135	COG0667	Aldo Keto reductase
FYC74_RS36175	COG0604	alcohol dehydrogenase
FYC74_RS36175	COG3321	synthase
FYC74_RS36190	COG0277	FAD linked oxidase domain protein
FYC74_RS36200	COG1819	glycosyl
FYC74_RS36245	COG0604	alcohol dehydrogenase
FYC74_RS36245	COG3321	synthase
FYC74_RS36350	COG1234	tRNA 3'-trailer cleavage