locus-tag	class	description
DXZ73_RS00180	COG2197	response regulator
DXZ73_RS00185	COG4585	Histidine kinase
DXZ73_RS00205	COG0477	Major facilitator Superfamily
DXZ73_RS00250	COG1086	Polysaccharide biosynthesis protein
DXZ73_RS00255	COG1012	belongs to the aldehyde dehydrogenase family
DXZ73_RS00320	COG0277	FAD linked oxidase domain protein
DXZ73_RS00460	COG2197	response regulator
DXZ73_RS00465	COG4585	Histidine kinase
DXZ73_RS00470	COG3599	regulation of cell shape
DXZ73_RS00565	COG3385	transposase activity
DXZ73_RS00580	COG4585	Histidine kinase
DXZ73_RS00585	COG2197	response regulator
DXZ73_RS00595	COG0577	efflux transmembrane transporter activity
DXZ73_RS00600	COG1136	(ABC) transporter
DXZ73_RS00635	COG2205	protein histidine kinase activity
DXZ73_RS00640	COG0745	RESPONSE REGULATOR receiver
DXZ73_RS00650	COG0577	efflux transmembrane transporter activity
DXZ73_RS00750	COG3547	Transposase (IS116 IS110 IS902 family)
DXZ73_RS00790	COG3226	Transcriptional regulator
DXZ73_RS00820	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DXZ73_RS00860	COG1733	regulation of RNA biosynthetic process
DXZ73_RS00870	COG0586	Pfam SNARE associated Golgi protein
DXZ73_RS00895	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DXZ73_RS00900	COG1686	Belongs to the peptidase S11 family
DXZ73_RS00905	COG0768	penicillin binding
DXZ73_RS00915	COG0583	DNA-binding transcription factor activity
DXZ73_RS00960	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DXZ73_RS00965	COG2188	Transcriptional regulator
DXZ73_RS00970	COG3104	oligopeptide transport
DXZ73_RS00975	COG2205	protein histidine kinase activity
DXZ73_RS00980	COG0745	RESPONSE REGULATOR receiver
DXZ73_RS00985	COG0577	efflux transmembrane transporter activity
DXZ73_RS00990	COG1136	(ABC) transporter
DXZ73_RS01015	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DXZ73_RS01020	COG0577	efflux transmembrane transporter activity
DXZ73_RS01020	COG1136	(ABC) transporter
DXZ73_RS01025	COG1136	(ABC) transporter
DXZ73_RS01040	COG0745	RESPONSE REGULATOR receiver
DXZ73_RS01045	COG2205	protein histidine kinase activity
DXZ73_RS01050	COG0745	RESPONSE REGULATOR receiver
DXZ73_RS01055	COG2205	protein histidine kinase activity
DXZ73_RS01065	COG0577	efflux transmembrane transporter activity
DXZ73_RS01065	COG1136	(ABC) transporter
DXZ73_RS01070	COG1136	(ABC) transporter
DXZ73_RS01090	COG1063	alcohol dehydrogenase
DXZ73_RS01100	COG0583	DNA-binding transcription factor activity
DXZ73_RS01115	COG5002	protein histidine kinase activity
DXZ73_RS01120	COG1764	response to oxidative stress
DXZ73_RS01135	COG1115	amino acid carrier protein
DXZ73_RS01140	COG4585	Histidine kinase
DXZ73_RS01155	COG0667	Aldo Keto reductase
DXZ73_RS01170	COG3385	transposase activity
DXZ73_RS01205	COG4213	ABC transporter substrate-binding protein
DXZ73_RS01215	COG4214	carbohydrate transport
DXZ73_RS01240	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DXZ73_RS01245	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DXZ73_RS01250	COG4585	Histidine kinase
DXZ73_RS01255	COG2197	response regulator
DXZ73_RS01285	COG1136	(ABC) transporter
DXZ73_RS01285	COG0577	efflux transmembrane transporter activity
DXZ73_RS01290	COG1136	(ABC) transporter
DXZ73_RS01290	COG0577	efflux transmembrane transporter activity
DXZ73_RS01295	COG0745	RESPONSE REGULATOR receiver
DXZ73_RS01300	COG2205	protein histidine kinase activity
DXZ73_RS01340	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DXZ73_RS01355	COG1196	nuclear chromosome segregation
DXZ73_RS01355	COG0741	lytic transglycosylase activity
DXZ73_RS01355	COG0739	heme binding
DXZ73_RS01365	COG0464	growth
DXZ73_RS01430	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DXZ73_RS01435	COG0134	indole-3-glycerol-phosphate synthase activity
DXZ73_RS01440	COG0135	phosphoribosylanthranilate isomerase activity
DXZ73_RS01455	COG3104	oligopeptide transport
DXZ73_RS01465	COG1115	amino acid carrier protein
DXZ73_RS01480	COG1126	abc transporter atp-binding protein
DXZ73_RS01485	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DXZ73_RS01490	COG0765	amino acid transport
DXZ73_RS01495	COG0765	amino acid transport
DXZ73_RS01500	COG2205	protein histidine kinase activity
DXZ73_RS01505	COG0745	RESPONSE REGULATOR receiver
DXZ73_RS01510	COG0577	efflux transmembrane transporter activity
DXZ73_RS01515	COG0577	efflux transmembrane transporter activity
DXZ73_RS01520	COG1136	(ABC) transporter
DXZ73_RS01590	COG4106	trans-aconitate 2-methyltransferase activity
DXZ73_RS01650	COG0535	radical SAM domain protein
DXZ73_RS01705	COG1278	Cold shock
DXZ73_RS01725	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DXZ73_RS01800	COG1674	ftsk spoiiie
DXZ73_RS01870	COG1215	transferase activity, transferring glycosyl groups
DXZ73_RS02075	COG0438	transferase activity, transferring glycosyl groups
DXZ73_RS02095	COG0583	DNA-binding transcription factor activity
DXZ73_RS02120	COG3629	intracellular signal transduction
DXZ73_RS02120	COG3903	Transcriptional regulator
DXZ73_RS02125	COG0596	Alpha beta hydrolase
DXZ73_RS02145	COG0148	phosphopyruvate hydratase activity
DXZ73_RS02155	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DXZ73_RS02165	COG0438	transferase activity, transferring glycosyl groups
DXZ73_RS02180	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
DXZ73_RS02215	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DXZ73_RS02235	COG0789	Transcriptional regulator
DXZ73_RS02280	COG0277	FAD linked oxidase domain protein
DXZ73_RS02340	COG2070	2-Nitropropane dioxygenase
DXZ73_RS02340	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DXZ73_RS02345	COG1846	Transcriptional regulator
DXZ73_RS02355	COG0702	epimerase
DXZ73_RS02360	COG1733	regulation of RNA biosynthetic process
DXZ73_RS02400	COG0318	PFAM AMP-dependent synthetase and ligase
DXZ73_RS02405	COG3962	Belongs to the TPP enzyme family
DXZ73_RS02410	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DXZ73_RS02420	COG0156	8-amino-7-oxononanoate synthase activity
DXZ73_RS02430	COG1028	Short-chain dehydrogenase reductase Sdr
DXZ73_RS02435	COG1028	Short-chain dehydrogenase reductase Sdr
DXZ73_RS02440	COG2211	Major facilitator Superfamily
DXZ73_RS02510	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DXZ73_RS02545	COG0445	tRNA wobble uridine modification
DXZ73_RS02560	COG3467	pyridoxamine 5'-phosphate
DXZ73_RS02570	COG0436	Aminotransferase
DXZ73_RS02575	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DXZ73_RS02595	COG0587	DNA-directed DNA polymerase activity
DXZ73_RS02610	COG3619	membrane
DXZ73_RS02635	COG1335	isochorismatase
DXZ73_RS02675	COG0477	Major facilitator Superfamily
DXZ73_RS02695	COG0789	Transcriptional regulator
DXZ73_RS02740	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DXZ73_RS02785	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DXZ73_RS02790	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DXZ73_RS02805	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
DXZ73_RS02830	COG1028	Short-chain dehydrogenase reductase Sdr
DXZ73_RS02835	COG1522	sequence-specific DNA binding
DXZ73_RS02885	COG4941	Belongs to the sigma-70 factor family
DXZ73_RS02910	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DXZ73_RS02955	COG1051	belongs to the nudix hydrolase family
DXZ73_RS02995	COG3293	Transposase
DXZ73_RS03005	COG3629	intracellular signal transduction
DXZ73_RS03005	COG3903	Transcriptional regulator
DXZ73_RS03020	COG1316	TRANSCRIPTIONal
DXZ73_RS03080	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
DXZ73_RS03110	COG0574	Belongs to the PEP-utilizing enzyme family
DXZ73_RS03110	COG3848	Pyruvate phosphate dikinase
DXZ73_RS03140	COG0596	Alpha beta hydrolase
DXZ73_RS03140	COG2945	thiolester hydrolase activity
DXZ73_RS03145	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DXZ73_RS03155	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DXZ73_RS03155	COG3321	synthase
DXZ73_RS03160	COG2226	methyltransferase
DXZ73_RS03160	COG1073	alpha beta
DXZ73_RS03175	COG1335	isochorismatase
DXZ73_RS03220	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DXZ73_RS03345	COG2814	Major facilitator Superfamily
DXZ73_RS03355	COG2205	protein histidine kinase activity
DXZ73_RS03400	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DXZ73_RS03405	COG3170	Tfp pilus assembly protein FimV
DXZ73_RS03410	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DXZ73_RS03440	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DXZ73_RS03445	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DXZ73_RS03455	COG1028	Short-chain dehydrogenase reductase Sdr
DXZ73_RS03460	COG1620	l-lactate permease
DXZ73_RS03470	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DXZ73_RS03475	COG0247	lactate metabolic process
DXZ73_RS03475	COG0277	FAD linked oxidase domain protein
DXZ73_RS03480	COG0318	PFAM AMP-dependent synthetase and ligase
DXZ73_RS03485	COG1028	Short-chain dehydrogenase reductase Sdr
DXZ73_RS03520	COG2124	cytochrome p450
DXZ73_RS03525	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DXZ73_RS03550	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DXZ73_RS03555	COG3251	PFAM MbtH domain protein
DXZ73_RS03560	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
DXZ73_RS03565	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DXZ73_RS03605	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DXZ73_RS03615	COG1509	lysine 2,3-aminomutase activity
DXZ73_RS03620	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DXZ73_RS03655	COG0672	)-iron permease
DXZ73_RS03670	COG0640	Transcriptional regulator
DXZ73_RS03685	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DXZ73_RS03690	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DXZ73_RS03720	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DXZ73_RS03730	COG1595	DNA-templated transcription, initiation
DXZ73_RS03750	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DXZ73_RS03775	COG2070	2-Nitropropane dioxygenase
DXZ73_RS03775	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DXZ73_RS03785	COG0596	Alpha beta hydrolase
DXZ73_RS03795	COG0154	amidase activity
DXZ73_RS03815	COG1802	Transcriptional regulator
DXZ73_RS03820	COG1012	belongs to the aldehyde dehydrogenase family
DXZ73_RS03825	COG3938	Belongs to the proline racemase family
DXZ73_RS03830	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DXZ73_RS03850	COG0006	proline dipeptidase activity
DXZ73_RS03865	COG0252	asparaginase activity
DXZ73_RS03870	COG1027	Aspartate ammonia-lyase
DXZ73_RS03980	COG0644	oxidoreductase
DXZ73_RS03995	COG1132	(ABC) transporter
DXZ73_RS04010	COG2124	cytochrome p450
DXZ73_RS04045	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DXZ73_RS04070	COG3321	synthase
DXZ73_RS04070	COG1028	Short-chain dehydrogenase reductase Sdr
DXZ73_RS04070	COG0604	alcohol dehydrogenase
DXZ73_RS04120	COG2197	response regulator
DXZ73_RS04140	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DXZ73_RS04145	COG0456	acetyltransferase
DXZ73_RS04160	COG1652	LysM domain
DXZ73_RS04190	COG0673	inositol 2-dehydrogenase activity
DXZ73_RS04205	COG0477	Major facilitator Superfamily
DXZ73_RS04220	COG2205	protein histidine kinase activity
DXZ73_RS04225	COG0745	RESPONSE REGULATOR receiver
DXZ73_RS04235	COG2755	lipolytic protein G-D-S-L family
DXZ73_RS04235	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DXZ73_RS04285	COG0640	Transcriptional regulator
DXZ73_RS04295	COG0477	Major facilitator Superfamily
DXZ73_RS04370	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DXZ73_RS04375	COG1960	acyl-CoA dehydrogenase activity
DXZ73_RS04400	COG1028	Short-chain dehydrogenase reductase Sdr
DXZ73_RS04440	COG0745	RESPONSE REGULATOR receiver
DXZ73_RS04485	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DXZ73_RS04495	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DXZ73_RS04500	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DXZ73_RS04520	COG0367	asparagine synthase
DXZ73_RS04555	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DXZ73_RS04570	COG4310	Domain of unknown function (DUF2172)
DXZ73_RS04580	COG1215	transferase activity, transferring glycosyl groups
DXZ73_RS04595	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DXZ73_RS04605	COG1028	Short-chain dehydrogenase reductase Sdr
DXZ73_RS04610	COG1028	Short-chain dehydrogenase reductase Sdr
DXZ73_RS04620	COG1309	transcriptional regulator
DXZ73_RS04660	COG4044	May play a role in the intracellular transport of hydrophobic ligands
DXZ73_RS04665	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DXZ73_RS04675	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DXZ73_RS04680	COG0477	Major facilitator Superfamily
DXZ73_RS04705	COG1073	alpha beta
DXZ73_RS04740	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DXZ73_RS04745	COG1309	transcriptional regulator
DXZ73_RS04750	COG0596	Alpha beta hydrolase
DXZ73_RS04780	COG1028	Short-chain dehydrogenase reductase Sdr
DXZ73_RS04790	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DXZ73_RS04795	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DXZ73_RS04800	COG4221	oxidoreductase activity
DXZ73_RS04860	COG1132	(ABC) transporter
DXZ73_RS04875	COG2409	Drug exporters of the RND superfamily
DXZ73_RS04880	COG1028	Short-chain dehydrogenase reductase Sdr
DXZ73_RS04880	COG3321	synthase
DXZ73_RS04880	COG0604	alcohol dehydrogenase
DXZ73_RS04915	COG2514	catechol 2,3-dioxygenase activity
DXZ73_RS04945	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DXZ73_RS04960	COG3629	intracellular signal transduction
DXZ73_RS04960	COG3903	Transcriptional regulator
DXZ73_RS04975	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DXZ73_RS04980	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DXZ73_RS05020	COG0542	response to heat
DXZ73_RS05075	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
DXZ73_RS05090	COG0330	HflC and HflK could
DXZ73_RS05095	COG0531	amino acid
DXZ73_RS05135	COG2015	COG2015, Alkyl sulfatase and related hydrolases
DXZ73_RS05140	COG0163	prenyltransferase activity
DXZ73_RS05160	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DXZ73_RS05205	COG0405	Gamma-glutamyltransferase
DXZ73_RS05250	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DXZ73_RS05265	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DXZ73_RS05270	COG2066	Belongs to the glutaminase family
DXZ73_RS05305	COG1063	alcohol dehydrogenase
DXZ73_RS05335	COG1660	Displays ATPase and GTPase activities
DXZ73_RS05340	COG0251	oxidation-reduction process
DXZ73_RS05345	COG2249	NAD(P)H dehydrogenase (quinone) activity
DXZ73_RS05370	COG1136	(ABC) transporter
DXZ73_RS05385	COG1819	glycosyl
DXZ73_RS05395	COG0477	Major facilitator Superfamily
DXZ73_RS05420	COG2124	cytochrome p450
DXZ73_RS05440	COG2124	cytochrome p450
DXZ73_RS05455	COG1028	Short-chain dehydrogenase reductase Sdr
DXZ73_RS05475	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DXZ73_RS05505	COG3511	phospholipase C
DXZ73_RS05515	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DXZ73_RS05515	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DXZ73_RS05540	COG2072	flavoprotein involved in K transport
DXZ73_RS05550	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DXZ73_RS05605	COG1857	crispr-associated protein
DXZ73_RS05620	COG1518	maintenance of DNA repeat elements
DXZ73_RS05625	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DXZ73_RS05650	COG1366	Belongs to the anti-sigma-factor antagonist family
DXZ73_RS05650	COG2208	phosphoserine phosphatase activity
DXZ73_RS05650	COG2172	sigma factor antagonist activity
DXZ73_RS05660	COG0477	Major facilitator Superfamily
DXZ73_RS05670	COG0589	response to stress
DXZ73_RS05680	COG0583	DNA-binding transcription factor activity
DXZ73_RS05685	COG0109	protoheme IX farnesyltransferase activity
DXZ73_RS05735	COG0589	response to stress
DXZ73_RS05745	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DXZ73_RS05750	COG3226	Transcriptional regulator
DXZ73_RS05755	COG0596	Alpha beta hydrolase
DXZ73_RS05770	COG1129	ABC transporter
DXZ73_RS05775	COG1172	Belongs to the binding-protein-dependent transport system permease family
DXZ73_RS05820	COG0076	glutamate decarboxylase activity
DXZ73_RS05830	COG2267	carboxylic ester hydrolase activity
DXZ73_RS05835	COG2124	cytochrome p450
DXZ73_RS05855	COG0387	Pfam Sodium calcium exchanger
DXZ73_RS05860	COG1129	ABC transporter
DXZ73_RS05860	COG0842	Transport permease protein
DXZ73_RS05945	COG2318	DinB family
DXZ73_RS05955	COG3537	Alpha-1,2-mannosidase
DXZ73_RS05960	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DXZ73_RS05990	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DXZ73_RS06000	COG0028	Belongs to the TPP enzyme family
DXZ73_RS06005	COG0531	amino acid
DXZ73_RS06015	COG1121	(ABC) transporter
DXZ73_RS06020	COG1321	iron dependent repressor
DXZ73_RS06020	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DXZ73_RS06145	COG0318	PFAM AMP-dependent synthetase and ligase
DXZ73_RS06155	COG0300	oxidoreductase activity
DXZ73_RS06160	COG2814	Major facilitator Superfamily
DXZ73_RS06165	COG0318	PFAM AMP-dependent synthetase and ligase
DXZ73_RS06170	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DXZ73_RS06175	COG1268	BioY protein
DXZ73_RS06180	COG1122	ATPase activity
DXZ73_RS06195	COG0745	RESPONSE REGULATOR receiver
DXZ73_RS06200	COG0243	molybdopterin cofactor binding
DXZ73_RS06205	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DXZ73_RS06210	COG2146	nitrite reductase [NAD(P)H] activity
DXZ73_RS06210	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DXZ73_RS06215	COG2223	nitrite transmembrane transporter activity
DXZ73_RS06235	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DXZ73_RS06235	COG1024	Enoyl-CoA hydratase
DXZ73_RS06280	COG2197	response regulator
DXZ73_RS06295	COG0464	growth
DXZ73_RS06335	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DXZ73_RS06490	COG0318	PFAM AMP-dependent synthetase and ligase
DXZ73_RS06495	COG2813	Specifically methylates the guanine in position
DXZ73_RS06510	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DXZ73_RS06540	COG4106	trans-aconitate 2-methyltransferase activity
DXZ73_RS06555	COG0745	RESPONSE REGULATOR receiver
DXZ73_RS06560	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DXZ73_RS06565	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
DXZ73_RS06575	COG2208	phosphoserine phosphatase activity
DXZ73_RS06575	COG2770	Histidine kinase
DXZ73_RS06580	COG1605	Chorismate mutase
DXZ73_RS06585	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
DXZ73_RS06595	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DXZ73_RS06600	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DXZ73_RS06600	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DXZ73_RS06630	COG1131	(ABC) transporter
DXZ73_RS06630	COG0842	Transport permease protein
DXZ73_RS06630	COG1716	ATPase activity
DXZ73_RS06755	COG3547	Transposase (IS116 IS110 IS902 family)
DXZ73_RS06885	COG3953	SLT domain
DXZ73_RS06885	COG5280	Phage tail tape measure protein TP901
DXZ73_RS06910	COG0113	porphobilinogen synthase activity
DXZ73_RS06915	COG0181	hydroxymethylbilane synthase activity
DXZ73_RS06925	COG0181	hydroxymethylbilane synthase activity
DXZ73_RS06940	COG1064	alcohol dehydrogenase
DXZ73_RS06950	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DXZ73_RS06965	COG0823	Involved in the tonB-independent uptake of proteins
DXZ73_RS06970	COG2124	cytochrome p450
DXZ73_RS07005	COG0791	NLP P60 protein
DXZ73_RS07010	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
DXZ73_RS07010	COG3261	NADH dehydrogenase
DXZ73_RS07015	COG0651	ATP synthesis coupled electron transport
DXZ73_RS07025	COG0650	Formate hydrogenlyase subunit 4
DXZ73_RS07035	COG3260	NADH ubiquinone oxidoreductase 20
DXZ73_RS07070	COG1309	transcriptional regulator
DXZ73_RS07080	COG2205	protein histidine kinase activity
DXZ73_RS07190	COG2813	Specifically methylates the guanine in position
DXZ73_RS07245	COG1250	3-hydroxyacyl-CoA dehydrogenase
DXZ73_RS07270	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DXZ73_RS07280	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DXZ73_RS07280	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DXZ73_RS07285	COG4221	oxidoreductase activity
DXZ73_RS07285	COG0300	oxidoreductase activity
DXZ73_RS07285	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DXZ73_RS07285	COG3321	synthase
DXZ73_RS07290	COG0367	asparagine synthase
DXZ73_RS07305	COG3629	intracellular signal transduction
DXZ73_RS07310	COG2376	Dihydroxyacetone kinase
DXZ73_RS07345	COG0586	Pfam SNARE associated Golgi protein
DXZ73_RS07395	COG3321	synthase
DXZ73_RS07395	COG0604	alcohol dehydrogenase
DXZ73_RS07400	COG3321	synthase
DXZ73_RS07400	COG0604	alcohol dehydrogenase
DXZ73_RS07405	COG0604	alcohol dehydrogenase
DXZ73_RS07405	COG3321	synthase
DXZ73_RS07430	COG0477	Major facilitator Superfamily
DXZ73_RS07435	COG0596	Alpha beta hydrolase
DXZ73_RS07460	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DXZ73_RS07470	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DXZ73_RS07475	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
DXZ73_RS07480	COG0628	permease
DXZ73_RS07490	COG4106	trans-aconitate 2-methyltransferase activity
DXZ73_RS07505	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DXZ73_RS07515	COG1051	belongs to the nudix hydrolase family
DXZ73_RS07525	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DXZ73_RS07530	COG1215	transferase activity, transferring glycosyl groups
DXZ73_RS07580	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DXZ73_RS07605	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
DXZ73_RS07625	COG2255	four-way junction helicase activity
DXZ73_RS07635	COG2340	Cysteine-rich secretory protein family
DXZ73_RS07675	COG1024	Enoyl-CoA hydratase
DXZ73_RS07675	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DXZ73_RS07695	COG1309	transcriptional regulator
DXZ73_RS07715	COG2824	Alkylphosphonate utilization operon protein PhnA
DXZ73_RS07720	COG2365	Tyrosine phosphatase family
DXZ73_RS07725	COG2197	response regulator
DXZ73_RS07730	COG4585	Histidine kinase
DXZ73_RS07735	COG1131	(ABC) transporter
DXZ73_RS07745	COG1733	regulation of RNA biosynthetic process
DXZ73_RS07800	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DXZ73_RS07810	COG0702	epimerase
DXZ73_RS07840	COG0793	Belongs to the peptidase S41A family
DXZ73_RS07860	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DXZ73_RS07870	COG0583	DNA-binding transcription factor activity
DXZ73_RS07895	COG3629	intracellular signal transduction
DXZ73_RS07895	COG3903	Transcriptional regulator
DXZ73_RS07900	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
DXZ73_RS07905	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DXZ73_RS07995	COG1793	dna ligase
DXZ73_RS08000	COG0431	NADPH-dependent FMN reductase
DXZ73_RS08070	COG1316	TRANSCRIPTIONal
DXZ73_RS08090	COG3979	chitinase
DXZ73_RS08125	COG1278	Cold shock
DXZ73_RS08135	COG1476	TRANSCRIPTIONal
DXZ73_RS08150	COG0583	DNA-binding transcription factor activity
DXZ73_RS08230	COG3629	intracellular signal transduction
DXZ73_RS08230	COG3903	Transcriptional regulator
DXZ73_RS08270	COG0791	NLP P60 protein
DXZ73_RS08275	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
DXZ73_RS08300	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DXZ73_RS08300	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
DXZ73_RS08315	COG0726	polysaccharide deacetylase
DXZ73_RS08325	COG3012	SEC-C Motif Domain Protein
DXZ73_RS08345	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DXZ73_RS08350	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DXZ73_RS08360	COG0438	transferase activity, transferring glycosyl groups
DXZ73_RS08400	COG0142	geranyltranstransferase activity
DXZ73_RS08435	COG0510	thiamine kinase activity
DXZ73_RS08505	COG2070	2-Nitropropane dioxygenase
DXZ73_RS08510	COG0515	serine threonine protein kinase
DXZ73_RS08520	COG0318	PFAM AMP-dependent synthetase and ligase
DXZ73_RS08530	COG2205	protein histidine kinase activity
DXZ73_RS08540	COG4221	oxidoreductase activity
DXZ73_RS08565	COG3629	intracellular signal transduction
DXZ73_RS08565	COG3903	Transcriptional regulator
DXZ73_RS08585	COG1960	acyl-CoA dehydrogenase activity
DXZ73_RS08640	COG1028	Short-chain dehydrogenase reductase Sdr
DXZ73_RS08645	COG0640	Transcriptional regulator
DXZ73_RS08650	COG0181	hydroxymethylbilane synthase activity
DXZ73_RS08675	COG2197	response regulator
DXZ73_RS08695	COG1960	acyl-CoA dehydrogenase activity
DXZ73_RS08705	COG0242	peptide deformylase activity
DXZ73_RS08715	COG3442	glutamine amidotransferase
DXZ73_RS08720	COG0205	6-phosphofructokinase activity
DXZ73_RS08740	COG0829	nickel cation binding
DXZ73_RS08745	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
DXZ73_RS08750	COG0830	nickel cation binding
DXZ73_RS08755	COG0804	urea catabolic process
DXZ73_RS08760	COG0832	Belongs to the urease beta subunit family
DXZ73_RS08765	COG0831	urea catabolic process
DXZ73_RS08795	COG0156	8-amino-7-oxononanoate synthase activity
DXZ73_RS08800	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DXZ73_RS08805	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DXZ73_RS08810	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DXZ73_RS08845	COG1595	DNA-templated transcription, initiation
DXZ73_RS08850	COG1028	Short-chain dehydrogenase reductase Sdr
DXZ73_RS08855	COG2188	Transcriptional regulator
DXZ73_RS08860	COG1940	carbohydrate kinase activity
DXZ73_RS08865	COG3663	DNA glycosylase
DXZ73_RS08870	COG1970	mechanosensitive ion channel activity
DXZ73_RS08875	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DXZ73_RS08880	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DXZ73_RS08905	COG1522	sequence-specific DNA binding
DXZ73_RS08910	COG0419	ATPase involved in DNA repair
DXZ73_RS08915	COG0420	3'-5' exonuclease activity
DXZ73_RS08935	COG0583	DNA-binding transcription factor activity
DXZ73_RS08945	COG1739	Uncharacterized protein family UPF0029
DXZ73_RS08950	COG1832	CoA-binding protein
DXZ73_RS08960	COG0367	asparagine synthase
DXZ73_RS08975	COG0110	maltose O-acetyltransferase activity
DXZ73_RS09010	COG0367	asparagine synthase
DXZ73_RS09015	COG0010	Belongs to the arginase family
DXZ73_RS09020	COG2175	clavaminate synthase activity
DXZ73_RS09040	COG0667	Aldo Keto reductase
DXZ73_RS09060	COG3903	Transcriptional regulator
DXZ73_RS09060	COG3629	intracellular signal transduction
DXZ73_RS09080	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DXZ73_RS09105	COG0604	alcohol dehydrogenase
DXZ73_RS09105	COG3321	synthase
DXZ73_RS09115	COG3321	synthase
DXZ73_RS09115	COG0604	alcohol dehydrogenase
DXZ73_RS09175	COG1024	Enoyl-CoA hydratase
DXZ73_RS09210	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DXZ73_RS09210	COG1796	DNA polymerase
DXZ73_RS09215	COG3285	dna ligase
DXZ73_RS09215	COG1793	dna ligase
DXZ73_RS09220	COG3285	dna ligase
DXZ73_RS09220	COG1793	dna ligase
DXZ73_RS09225	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
DXZ73_RS09230	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
DXZ73_RS09230	COG1672	PFAM Archaeal ATPase
DXZ73_RS09290	COG2318	DinB family
DXZ73_RS09295	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DXZ73_RS09340	COG0583	DNA-binding transcription factor activity
DXZ73_RS09345	COG0697	spore germination
DXZ73_RS09375	COG1695	Transcriptional regulator
DXZ73_RS09405	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DXZ73_RS09405	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DXZ73_RS09415	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DXZ73_RS09455	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DXZ73_RS09495	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DXZ73_RS09510	COG0675	Transposase, IS605 OrfB family
DXZ73_RS09520	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DXZ73_RS09530	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
DXZ73_RS09535	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DXZ73_RS09555	COG0642	Histidine kinase
DXZ73_RS09580	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
DXZ73_RS09595	COG2186	Transcriptional regulator
DXZ73_RS09600	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
DXZ73_RS09605	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
DXZ73_RS09610	COG1984	allophanate hydrolase subunit 2
DXZ73_RS09645	COG0745	RESPONSE REGULATOR receiver
DXZ73_RS09650	COG2205	protein histidine kinase activity
DXZ73_RS09675	COG1793	dna ligase
DXZ73_RS09680	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
DXZ73_RS09695	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DXZ73_RS09715	COG2186	Transcriptional regulator
DXZ73_RS09730	COG3030	protein affecting phage T7 exclusion by the F plasmid
DXZ73_RS09735	COG0463	Glycosyl transferase, family 2
DXZ73_RS09760	COG1960	acyl-CoA dehydrogenase activity
DXZ73_RS09810	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DXZ73_RS09815	COG1120	ATPase activity
DXZ73_RS09860	COG2124	cytochrome p450
DXZ73_RS09905	COG1012	belongs to the aldehyde dehydrogenase family
DXZ73_RS09955	COG1181	Belongs to the D-alanine--D-alanine ligase family
DXZ73_RS09995	COG0367	asparagine synthase
DXZ73_RS10000	COG0475	glutathione-regulated potassium exporter activity
DXZ73_RS10010	COG0454	-acetyltransferase
DXZ73_RS10075	COG1024	Enoyl-CoA hydratase
DXZ73_RS10085	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DXZ73_RS10090	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DXZ73_RS10095	COG0318	PFAM AMP-dependent synthetase and ligase
DXZ73_RS10100	COG1032	radical SAM domain protein
DXZ73_RS10180	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DXZ73_RS10185	COG0140	phosphoribosyl-ATP diphosphatase activity
DXZ73_RS10190	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DXZ73_RS10195	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DXZ73_RS10195	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DXZ73_RS10200	COG3201	nicotinamide mononucleotide transporter
DXZ73_RS10215	COG0738	Major facilitator superfamily
DXZ73_RS10225	COG2233	PERMEase
DXZ73_RS10240	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DXZ73_RS10255	COG0531	amino acid
DXZ73_RS10280	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DXZ73_RS10290	COG1940	carbohydrate kinase activity
DXZ73_RS10295	COG0667	Aldo Keto reductase
DXZ73_RS10320	COG2390	Transcriptional regulator
DXZ73_RS10325	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DXZ73_RS10335	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DXZ73_RS10350	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DXZ73_RS10375	COG0284	orotidine-5'-phosphate decarboxylase activity
DXZ73_RS10380	COG0167	dihydroorotate dehydrogenase activity
DXZ73_RS10385	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DXZ73_RS10390	COG0505	Belongs to the CarA family
DXZ73_RS10400	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DXZ73_RS10405	COG0540	Belongs to the ATCase OTCase family
DXZ73_RS10410	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DXZ73_RS10420	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DXZ73_RS10425	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DXZ73_RS10430	COG0006	proline dipeptidase activity
DXZ73_RS10440	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
DXZ73_RS10445	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DXZ73_RS10450	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DXZ73_RS10455	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DXZ73_RS10460	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DXZ73_RS10470	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DXZ73_RS10475	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DXZ73_RS10495	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DXZ73_RS10515	COG0124	histidyl-tRNA synthetase
DXZ73_RS10530	COG1196	nuclear chromosome segregation
DXZ73_RS10535	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DXZ73_RS10545	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DXZ73_RS10550	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DXZ73_RS10555	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DXZ73_RS10565	COG2255	four-way junction helicase activity
DXZ73_RS10570	COG0632	four-way junction helicase activity
DXZ73_RS10575	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
DXZ73_RS10580	COG0217	transcriptional regulatory protein
DXZ73_RS10585	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
DXZ73_RS10590	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
DXZ73_RS10605	COG0438	transferase activity, transferring glycosyl groups
DXZ73_RS10610	COG1560	Kdo2-lipid A biosynthetic process
DXZ73_RS10615	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DXZ73_RS10635	COG0726	polysaccharide deacetylase
DXZ73_RS10645	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DXZ73_RS10660	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DXZ73_RS10715	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DXZ73_RS10760	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DXZ73_RS10765	COG1648	precorrin-2 dehydrogenase activity
DXZ73_RS10765	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DXZ73_RS10770	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DXZ73_RS10785	COG1464	Belongs to the NlpA lipoprotein family
DXZ73_RS10790	COG2011	ABC-type metal ion transport system permease component
DXZ73_RS10795	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DXZ73_RS10835	COG0477	Major facilitator Superfamily
DXZ73_RS10845	COG0165	Argininosuccinate lyase
DXZ73_RS10850	COG0137	argininosuccinate synthase activity
DXZ73_RS10860	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DXZ73_RS10865	COG1438	arginine binding
DXZ73_RS10870	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DXZ73_RS10875	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DXZ73_RS10880	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DXZ73_RS10885	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DXZ73_RS10890	COG2770	Histidine kinase
DXZ73_RS10890	COG2208	phosphoserine phosphatase activity
DXZ73_RS10895	COG0772	Belongs to the SEDS family
DXZ73_RS10900	COG2838	Isocitrate dehydrogenase
DXZ73_RS10905	COG2197	response regulator
DXZ73_RS10910	COG4585	Histidine kinase
DXZ73_RS10935	COG1595	DNA-templated transcription, initiation
DXZ73_RS10950	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DXZ73_RS10955	COG0697	spore germination
DXZ73_RS10965	COG1649	PFAM Uncharacterised BCR, COG1649
DXZ73_RS10990	COG0477	Major facilitator Superfamily
DXZ73_RS11000	COG0072	phenylalanine-tRNA ligase activity
DXZ73_RS11000	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DXZ73_RS11005	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DXZ73_RS11010	COG5002	protein histidine kinase activity
DXZ73_RS11015	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DXZ73_RS11020	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DXZ73_RS11025	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DXZ73_RS11030	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DXZ73_RS11040	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DXZ73_RS11050	COG1404	Belongs to the peptidase S8 family
DXZ73_RS11075	COG1012	belongs to the aldehyde dehydrogenase family
DXZ73_RS11090	COG0531	amino acid
DXZ73_RS11095	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DXZ73_RS11235	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DXZ73_RS11245	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DXZ73_RS11265	COG4176	ABC-type proline glycine betaine transport system permease component
DXZ73_RS11270	COG4175	Glycine betaine
DXZ73_RS11270	COG0517	IMP dehydrogenase activity
DXZ73_RS11275	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DXZ73_RS11300	COG0805	protein transport
DXZ73_RS11305	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DXZ73_RS11325	COG2378	regulation of single-species biofilm formation
DXZ73_RS11340	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
DXZ73_RS11350	COG1609	Transcriptional regulator
DXZ73_RS11355	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
DXZ73_RS11360	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
DXZ73_RS11370	COG4122	O-methyltransferase activity
DXZ73_RS11375	COG1222	aaa ATPase
DXZ73_RS11395	COG0517	IMP dehydrogenase activity
DXZ73_RS11395	COG1994	Peptidase M50
DXZ73_RS11405	COG2197	response regulator
DXZ73_RS11415	COG4166	transmembrane transport
DXZ73_RS11435	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DXZ73_RS11440	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DXZ73_RS11445	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DXZ73_RS11450	COG1414	Transcriptional regulator
DXZ73_RS11455	COG0646	methionine synthase
DXZ73_RS11455	COG1410	methionine synthase
DXZ73_RS11505	COG2154	pterin-4-alpha-carbinolamine dehydratase
DXZ73_RS11515	COG0215	cysteine-tRNA ligase activity
DXZ73_RS11535	COG0598	Magnesium transport protein CorA
DXZ73_RS11540	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DXZ73_RS11545	COG0667	Aldo Keto reductase
DXZ73_RS11575	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DXZ73_RS11595	COG1132	(ABC) transporter
DXZ73_RS11600	COG1132	(ABC) transporter
DXZ73_RS11620	COG3173	Aminoglycoside phosphotransferase
DXZ73_RS11635	COG2175	clavaminate synthase activity
DXZ73_RS11645	COG0673	inositol 2-dehydrogenase activity
DXZ73_RS11650	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DXZ73_RS11710	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
DXZ73_RS11740	COG1960	acyl-CoA dehydrogenase activity
DXZ73_RS11755	COG0318	PFAM AMP-dependent synthetase and ligase
DXZ73_RS11815	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
DXZ73_RS11820	COG2188	Transcriptional regulator
DXZ73_RS11850	COG0515	serine threonine protein kinase
DXZ73_RS11870	COG0463	Glycosyl transferase, family 2
DXZ73_RS11875	COG1215	transferase activity, transferring glycosyl groups
DXZ73_RS11900	COG1725	Transcriptional regulator
DXZ73_RS11905	COG0367	asparagine synthase
DXZ73_RS11910	COG0019	diaminopimelate decarboxylase activity
DXZ73_RS11915	COG4264	IucA IucC family
DXZ73_RS11960	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
DXZ73_RS12005	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DXZ73_RS12035	COG1819	glycosyl
DXZ73_RS12040	COG0039	L-malate dehydrogenase activity
DXZ73_RS12060	COG0242	peptide deformylase activity
DXZ73_RS12090	COG0601	transmembrane transport
DXZ73_RS12095	COG4166	transmembrane transport
DXZ73_RS12100	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DXZ73_RS12115	COG0330	HflC and HflK could
DXZ73_RS12130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DXZ73_RS12135	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DXZ73_RS12150	COG1799	cell septum assembly
DXZ73_RS12155	COG1960	acyl-CoA dehydrogenase activity
DXZ73_RS12160	COG0477	Major facilitator Superfamily
DXZ73_RS12170	COG0671	phosphoesterase, PA-phosphatase related
DXZ73_RS12180	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DXZ73_RS12195	COG0438	transferase activity, transferring glycosyl groups
DXZ73_RS12210	COG1160	GTP binding
DXZ73_RS12220	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DXZ73_RS12235	COG1187	pseudouridine synthase activity
DXZ73_RS12240	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DXZ73_RS12245	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DXZ73_RS12260	COG0686	Belongs to the AlaDH PNT family
DXZ73_RS12265	COG3903	Transcriptional regulator
DXZ73_RS12265	COG3629	intracellular signal transduction
DXZ73_RS12270	COG0494	nUDIX hydrolase
DXZ73_RS12275	COG0504	CTP synthase activity
DXZ73_RS12280	COG3387	PFAM Glycoside hydrolase 15-related
DXZ73_RS12285	COG2814	Major facilitator Superfamily
DXZ73_RS12295	COG0297	glycogen (starch) synthase activity
DXZ73_RS12300	COG0497	DNA recombination
DXZ73_RS12310	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DXZ73_RS12330	COG1120	ATPase activity
DXZ73_RS12335	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DXZ73_RS12340	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DXZ73_RS12355	COG0647	UMP catabolic process
DXZ73_RS12385	COG2094	Belongs to the DNA glycosylase MPG family
DXZ73_RS12400	COG1881	PFAM PEBP family protein
DXZ73_RS12425	COG1119	ATPase activity
DXZ73_RS12445	COG2197	response regulator
DXZ73_RS12450	COG4585	Histidine kinase
DXZ73_RS12465	COG1131	(ABC) transporter
DXZ73_RS12465	COG1716	ATPase activity
DXZ73_RS12465	COG0842	Transport permease protein
DXZ73_RS12475	COG3830	Belongs to the UPF0237 family
DXZ73_RS12475	COG0560	Phosphoserine phosphatase
DXZ73_RS12495	COG2186	Transcriptional regulator
DXZ73_RS12505	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DXZ73_RS12510	COG1028	Short-chain dehydrogenase reductase Sdr
DXZ73_RS12525	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DXZ73_RS12545	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DXZ73_RS12550	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DXZ73_RS12570	COG1063	alcohol dehydrogenase
DXZ73_RS12635	COG1024	Enoyl-CoA hydratase
DXZ73_RS12645	COG0488	(ABC) transporter
DXZ73_RS12665	COG0235	Class ii aldolase
DXZ73_RS12680	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
DXZ73_RS12685	COG1492	cobalamin metabolic process
DXZ73_RS12700	COG1797	cobyrinic acid a,c-diamide synthase activity
DXZ73_RS12725	COG0385	Bile acid
DXZ73_RS12735	COG5285	phytanoyl-CoA dioxygenase
DXZ73_RS12740	COG1917	Cupin 2, conserved barrel domain protein
DXZ73_RS12765	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DXZ73_RS12775	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DXZ73_RS12790	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DXZ73_RS12795	COG2171	N-acyltransferase activity
DXZ73_RS12805	COG2957	Belongs to the agmatine deiminase family
DXZ73_RS12815	COG0822	iron-sulfur transferase activity
DXZ73_RS12820	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DXZ73_RS12825	COG0396	ATPase activity
DXZ73_RS12835	COG0719	Fe-S assembly protein
DXZ73_RS12850	COG1131	(ABC) transporter
DXZ73_RS12875	COG0109	protoheme IX farnesyltransferase activity
DXZ73_RS12885	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DXZ73_RS12900	COG0363	glucosamine-6-phosphate deaminase activity
DXZ73_RS12905	COG0166	Belongs to the GPI family
DXZ73_RS12920	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DXZ73_RS12925	COG0149	triose-phosphate isomerase activity
DXZ73_RS12930	COG0126	phosphoglycerate kinase activity
DXZ73_RS12935	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DXZ73_RS12945	COG1481	regulation of sporulation
DXZ73_RS12955	COG1660	Displays ATPase and GTPase activities
DXZ73_RS12960	COG0322	excinuclease ABC activity
DXZ73_RS12990	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DXZ73_RS13005	COG0477	Major facilitator Superfamily
DXZ73_RS13025	COG0556	nucleotide-excision repair
DXZ73_RS13030	COG0584	glycerophosphoryl diester phosphodiesterase
DXZ73_RS13035	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DXZ73_RS13045	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DXZ73_RS13045	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
DXZ73_RS13080	COG0237	dephospho-CoA kinase activity
DXZ73_RS13090	COG0539	negative regulation of cytoplasmic translation
DXZ73_RS13100	COG2226	methyltransferase
DXZ73_RS13105	COG1643	Atp-dependent helicase
DXZ73_RS13135	COG2050	protein possibly involved in aromatic compounds catabolism
DXZ73_RS13160	COG0411	ABC transporter
DXZ73_RS13200	COG0737	Belongs to the 5'-nucleotidase family
DXZ73_RS13215	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DXZ73_RS13225	COG0287	Prephenate dehydrogenase
DXZ73_RS13225	COG1605	Chorismate mutase
DXZ73_RS13235	COG1470	cell adhesion involved in biofilm formation
DXZ73_RS13235	COG0366	Alpha amylase catalytic
DXZ73_RS13245	COG2197	response regulator
DXZ73_RS13275	COG1215	transferase activity, transferring glycosyl groups
DXZ73_RS13280	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
DXZ73_RS13295	COG0070	glutamate synthase
DXZ73_RS13295	COG0067	glutamate synthase
DXZ73_RS13295	COG0069	glutamate synthase activity
DXZ73_RS13305	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DXZ73_RS13315	COG0159	tryptophan synthase activity
DXZ73_RS13320	COG0133	tryptophan synthase activity
DXZ73_RS13330	COG0134	indole-3-glycerol-phosphate synthase activity
DXZ73_RS13355	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DXZ73_RS13370	COG0107	imidazoleglycerol-phosphate synthase activity
DXZ73_RS13375	COG0251	oxidation-reduction process
DXZ73_RS13380	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DXZ73_RS13385	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DXZ73_RS13390	COG0131	Imidazoleglycerol-phosphate dehydratase
DXZ73_RS13395	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DXZ73_RS13400	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DXZ73_RS13410	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DXZ73_RS13415	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DXZ73_RS13440	COG0587	DNA-directed DNA polymerase activity
DXZ73_RS13445	COG1432	Conserved Protein
DXZ73_RS13495	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DXZ73_RS13510	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DXZ73_RS13525	COG1799	cell septum assembly
DXZ73_RS13545	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DXZ73_RS13550	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DXZ73_RS13560	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DXZ73_RS13565	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DXZ73_RS13575	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DXZ73_RS13580	COG0768	penicillin binding
DXZ73_RS13590	COG0275	rRNA processing
DXZ73_RS13600	COG0714	Associated with various cellular activities
DXZ73_RS13620	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DXZ73_RS13625	COG1309	transcriptional regulator
DXZ73_RS13635	COG1233	COG1233 Phytoene dehydrogenase and related
DXZ73_RS13650	COG0352	thiamine-phosphate diphosphorylase activity
DXZ73_RS13665	COG2022	thiamine diphosphate biosynthetic process
DXZ73_RS13665	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DXZ73_RS13675	COG2022	thiamine diphosphate biosynthetic process
DXZ73_RS13680	COG0515	serine threonine protein kinase
DXZ73_RS13680	COG2815	serine threonine protein kinase
DXZ73_RS13685	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
DXZ73_RS13690	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DXZ73_RS13695	COG2193	ferroxidase activity
DXZ73_RS13705	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
DXZ73_RS13720	COG0205	6-phosphofructokinase activity
DXZ73_RS13725	COG2197	response regulator
DXZ73_RS13730	COG4585	Histidine kinase
DXZ73_RS13755	COG1940	carbohydrate kinase activity
DXZ73_RS13765	COG0003	Pfam Anion-transporting ATPase
DXZ73_RS13785	COG0438	transferase activity, transferring glycosyl groups
DXZ73_RS13830	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DXZ73_RS13835	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DXZ73_RS13840	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DXZ73_RS13845	COG0723	plastoquinol--plastocyanin reductase activity
DXZ73_RS13850	COG2010	Cytochrome c
DXZ73_RS13855	COG1845	cytochrome c oxidase, subunit III
DXZ73_RS13865	COG1376	ErfK ybiS ycfS ynhG family protein
DXZ73_RS13875	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DXZ73_RS13880	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DXZ73_RS13885	COG1104	cysteine desulfurase activity
DXZ73_RS13890	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DXZ73_RS13910	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
DXZ73_RS13915	COG2197	response regulator
DXZ73_RS13920	COG4585	Histidine kinase
DXZ73_RS13945	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DXZ73_RS13960	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DXZ73_RS13965	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DXZ73_RS13965	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DXZ73_RS13980	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
DXZ73_RS13985	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DXZ73_RS13990	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DXZ73_RS13995	COG0508	dehydrogenase complex catalyzes the overall conversion of
DXZ73_RS14010	COG1028	Short-chain dehydrogenase reductase Sdr
DXZ73_RS14020	COG1090	epimerase
DXZ73_RS14035	COG0321	lipoyl(octanoyl) transferase activity
DXZ73_RS14040	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DXZ73_RS14095	COG0745	RESPONSE REGULATOR receiver
DXZ73_RS14105	COG2197	response regulator
DXZ73_RS14115	COG2365	Tyrosine phosphatase family
DXZ73_RS14150	COG3833	ABC-type maltose transport systems, permease component
DXZ73_RS14155	COG0366	Alpha amylase catalytic
DXZ73_RS14170	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
DXZ73_RS14175	COG0174	glutamine synthetase
DXZ73_RS14185	COG2267	carboxylic ester hydrolase activity
DXZ73_RS14190	COG0531	amino acid
DXZ73_RS14200	COG2132	Multicopper oxidase
DXZ73_RS14210	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DXZ73_RS14210	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DXZ73_RS14225	COG2814	Major facilitator Superfamily
DXZ73_RS14240	COG0477	Major facilitator Superfamily
DXZ73_RS14245	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DXZ73_RS14265	COG1994	Peptidase M50
DXZ73_RS14375	COG4558	Periplasmic binding protein
DXZ73_RS14380	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DXZ73_RS14385	COG1120	ATPase activity
DXZ73_RS14390	COG2822	iron ion transport
DXZ73_RS14395	COG2837	iron assimilation
DXZ73_RS14400	COG0672	)-iron permease
DXZ73_RS14415	COG1309	transcriptional regulator
DXZ73_RS14425	COG1834	amidinotransferase
DXZ73_RS14435	COG2814	Major facilitator Superfamily
DXZ73_RS14440	COG3022	response to hydroperoxide
DXZ73_RS14445	COG0557	exoribonuclease II activity
DXZ73_RS14455	COG0789	Transcriptional regulator
DXZ73_RS14480	COG0800	Aldolase
DXZ73_RS14500	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DXZ73_RS14505	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
DXZ73_RS14525	COG2030	dehydratase
DXZ73_RS14530	COG4585	Histidine kinase
DXZ73_RS14535	COG2197	response regulator
DXZ73_RS14545	COG0860	N-Acetylmuramoyl-L-alanine amidase
DXZ73_RS14555	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DXZ73_RS14585	COG0438	transferase activity, transferring glycosyl groups
DXZ73_RS14590	COG1309	transcriptional regulator
DXZ73_RS14595	COG2197	response regulator
DXZ73_RS14600	COG1132	(ABC) transporter
DXZ73_RS14605	COG1132	(ABC) transporter
DXZ73_RS14615	COG0515	serine threonine protein kinase
DXZ73_RS14675	COG1657	PFAM Prenyltransferase squalene oxidase
DXZ73_RS14690	COG3845	ABC transporter
DXZ73_RS14715	COG0183	Belongs to the thiolase family
DXZ73_RS14720	COG2124	cytochrome p450
DXZ73_RS14765	COG1609	Transcriptional regulator
DXZ73_RS14770	COG2226	methyltransferase
DXZ73_RS14780	COG2318	DinB family
DXZ73_RS14810	COG2259	Doxx family
DXZ73_RS14835	COG0583	DNA-binding transcription factor activity
DXZ73_RS14880	COG1358	cellular component organization or biogenesis
DXZ73_RS14925	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
DXZ73_RS14935	COG0477	Major facilitator Superfamily
DXZ73_RS14940	COG1309	transcriptional regulator
DXZ73_RS14955	COG4585	Histidine kinase
DXZ73_RS14960	COG2197	response regulator
DXZ73_RS14965	COG0667	Aldo Keto reductase
DXZ73_RS14970	COG0789	Transcriptional regulator
DXZ73_RS14995	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DXZ73_RS15000	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DXZ73_RS15005	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DXZ73_RS15050	COG1285	pathogenesis
DXZ73_RS15115	COG1595	DNA-templated transcription, initiation
DXZ73_RS15120	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DXZ73_RS15125	COG1335	isochorismatase
DXZ73_RS15135	COG2130	NADP-dependent
DXZ73_RS15140	COG1764	response to oxidative stress
DXZ73_RS15145	COG2197	response regulator
DXZ73_RS15150	COG4585	Histidine kinase
DXZ73_RS15160	COG3903	Transcriptional regulator
DXZ73_RS15160	COG3629	intracellular signal transduction
DXZ73_RS15180	COG0406	alpha-ribazole phosphatase activity
DXZ73_RS15185	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DXZ73_RS15250	COG0604	alcohol dehydrogenase
DXZ73_RS15260	COG1475	DNA binding
DXZ73_RS15420	COG3547	Transposase (IS116 IS110 IS902 family)
DXZ73_RS15450	COG1011	Hydrolase
DXZ73_RS15455	COG0494	nUDIX hydrolase
DXZ73_RS15480	COG2815	serine threonine protein kinase
DXZ73_RS15480	COG0515	serine threonine protein kinase
DXZ73_RS15520	COG0537	adenosine 5'-monophosphoramidase activity
DXZ73_RS15765	COG1484	DNA-dependent DNA replication
DXZ73_RS15805	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DXZ73_RS15815	COG1434	Gram-negative-bacterium-type cell wall biogenesis
DXZ73_RS15870	COG0181	hydroxymethylbilane synthase activity
DXZ73_RS15875	COG0181	hydroxymethylbilane synthase activity
DXZ73_RS15890	COG1132	(ABC) transporter
DXZ73_RS16055	COG1070	Carbohydrate kinase
DXZ73_RS16060	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DXZ73_RS16065	COG0358	DNA primase activity
DXZ73_RS16075	COG0232	Belongs to the dGTPase family. Type 2 subfamily
DXZ73_RS16080	COG2949	membrane
DXZ73_RS16100	COG0300	oxidoreductase activity
DXZ73_RS16110	COG0531	amino acid
DXZ73_RS16115	COG2182	Extracellular solute-binding protein
DXZ73_RS16120	COG1175	transmembrane transport
DXZ73_RS16125	COG0395	ABC-type sugar transport system, permease component
DXZ73_RS16135	COG0574	Belongs to the PEP-utilizing enzyme family
DXZ73_RS16135	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DXZ73_RS16150	COG1846	Transcriptional regulator
DXZ73_RS16160	COG0477	Major facilitator Superfamily
DXZ73_RS16165	COG0667	Aldo Keto reductase
DXZ73_RS16175	COG0640	Transcriptional regulator
DXZ73_RS16180	COG2814	Major facilitator Superfamily
DXZ73_RS16205	COG2197	response regulator
DXZ73_RS16225	COG0423	glycine-tRNA ligase activity
DXZ73_RS16230	COG0803	Belongs to the bacterial solute-binding protein 9 family
DXZ73_RS16230	COG3443	Belongs to the bacterial solute-binding protein 9 family
DXZ73_RS16235	COG1121	(ABC) transporter
DXZ73_RS16240	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DXZ73_RS16250	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DXZ73_RS16255	COG1381	Involved in DNA repair and RecF pathway recombination
DXZ73_RS16270	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DXZ73_RS16285	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DXZ73_RS16310	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DXZ73_RS16325	COG1486	melibiose metabolic process
DXZ73_RS16335	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DXZ73_RS16345	COG0537	adenosine 5'-monophosphoramidase activity
DXZ73_RS16350	COG1234	tRNA 3'-trailer cleavage
DXZ73_RS16370	COG2197	response regulator
DXZ73_RS16475	COG3209	COG3209 Rhs family protein
DXZ73_RS16495	COG0484	heat shock protein binding
DXZ73_RS16500	COG1420	regulation of RNA biosynthetic process
DXZ73_RS16530	COG0481	GTPase activity
DXZ73_RS16535	COG0268	Binds directly to 16S ribosomal RNA
DXZ73_RS16550	COG1234	tRNA 3'-trailer cleavage
DXZ73_RS16555	COG1555	photosystem II stabilization
DXZ73_RS16555	COG1596	polysaccharide export
DXZ73_RS16560	COG1307	EDD domain protein, DegV family
DXZ73_RS16570	COG0495	leucyl-tRNA aminoacylation
DXZ73_RS16615	COG0588	phosphoglycerate mutase activity
DXZ73_RS16620	COG0799	negative regulation of ribosome biogenesis
DXZ73_RS16630	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DXZ73_RS16635	COG0501	Belongs to the peptidase M48B family
DXZ73_RS16650	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DXZ73_RS16660	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DXZ73_RS16670	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DXZ73_RS16675	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DXZ73_RS16680	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DXZ73_RS16685	COG1530	ribonuclease E activity
DXZ73_RS16705	COG0772	Belongs to the SEDS family
DXZ73_RS16710	COG0768	penicillin binding
DXZ73_RS16725	COG1077	Cell shape determining protein MreB Mrl
DXZ73_RS16730	COG0105	UTP biosynthetic process
DXZ73_RS16740	COG0285	dihydrofolate synthase activity
DXZ73_RS16745	COG0768	penicillin binding
DXZ73_RS16750	COG2205	protein histidine kinase activity
DXZ73_RS16755	COG0745	RESPONSE REGULATOR receiver
DXZ73_RS16765	COG1215	transferase activity, transferring glycosyl groups
DXZ73_RS16775	COG0525	valine-tRNA ligase activity
DXZ73_RS16810	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DXZ73_RS16815	COG0740	serine-type endopeptidase activity
DXZ73_RS16820	COG0740	serine-type endopeptidase activity
DXZ73_RS16825	COG0544	peptidyl-prolyl cis-trans isomerase activity
DXZ73_RS16845	COG3594	Acyltransferase
DXZ73_RS16860	COG4552	Acetyltransferase involved in intracellular survival and related
DXZ73_RS16875	COG1113	amino acid transport
DXZ73_RS16880	COG1268	BioY protein
DXZ73_RS16885	COG1113	amino acid transport
DXZ73_RS16890	COG1113	amino acid transport
DXZ73_RS16895	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DXZ73_RS16905	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DXZ73_RS17005	COG3291	Pkd domain containing protein
DXZ73_RS17005	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DXZ73_RS17015	COG0668	transmembrane transport
DXZ73_RS17020	COG1846	Transcriptional regulator
DXZ73_RS17020	COG1940	carbohydrate kinase activity
DXZ73_RS17030	COG1175	transmembrane transport
DXZ73_RS17040	COG1486	melibiose metabolic process
DXZ73_RS17065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DXZ73_RS17095	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DXZ73_RS17100	COG2346	COG2346, Truncated hemoglobins
DXZ73_RS17125	COG0629	single-stranded DNA binding
DXZ73_RS17145	COG3629	intracellular signal transduction
DXZ73_RS17145	COG3903	Transcriptional regulator
DXZ73_RS17150	COG0515	serine threonine protein kinase
DXZ73_RS17195	COG0702	epimerase
DXZ73_RS17215	COG1846	Transcriptional regulator
DXZ73_RS17220	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DXZ73_RS17225	COG1250	3-hydroxyacyl-CoA dehydrogenase
DXZ73_RS17230	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DXZ73_RS17325	COG2197	response regulator
DXZ73_RS17335	COG2423	ornithine cyclodeaminase activity
DXZ73_RS17345	COG1053	succinate dehydrogenase
DXZ73_RS17350	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DXZ73_RS17385	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DXZ73_RS17390	COG1993	acr, cog1993
DXZ73_RS17395	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DXZ73_RS17400	COG0583	DNA-binding transcription factor activity
DXZ73_RS17410	COG1289	transmembrane transporter activity
DXZ73_RS17420	COG3962	Belongs to the TPP enzyme family
DXZ73_RS17425	COG3718	enzyme involved in inositol metabolism
DXZ73_RS17445	COG0673	inositol 2-dehydrogenase activity
DXZ73_RS17450	COG0673	inositol 2-dehydrogenase activity
DXZ73_RS17475	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DXZ73_RS17490	COG0673	inositol 2-dehydrogenase activity
DXZ73_RS17525	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
DXZ73_RS17540	COG1946	Acyl-CoA thioesterase
DXZ73_RS17550	COG1309	transcriptional regulator
DXZ73_RS17555	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DXZ73_RS17570	COG1960	acyl-CoA dehydrogenase activity
DXZ73_RS17585	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DXZ73_RS17590	COG0589	response to stress
DXZ73_RS17605	COG4977	sequence-specific DNA binding
DXZ73_RS17610	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
DXZ73_RS17640	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DXZ73_RS17655	COG0406	alpha-ribazole phosphatase activity
DXZ73_RS17675	COG3547	Transposase (IS116 IS110 IS902 family)
DXZ73_RS17710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DXZ73_RS17725	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DXZ73_RS17725	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DXZ73_RS17730	COG4232	protein-disulfide reductase activity
DXZ73_RS17735	COG3397	chitin binding
DXZ73_RS17740	COG0791	NLP P60 protein
DXZ73_RS17740	COG0741	lytic transglycosylase activity
DXZ73_RS17790	COG0673	inositol 2-dehydrogenase activity
DXZ73_RS17795	COG4702	Belongs to the UPF0303 family
DXZ73_RS17805	COG0346	lactoylglutathione lyase activity
DXZ73_RS17845	COG0179	Fumarylacetoacetate (FAA) hydrolase
DXZ73_RS17850	COG0706	membrane insertase activity
DXZ73_RS17860	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DXZ73_RS17870	COG2733	membrane
DXZ73_RS17900	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DXZ73_RS17910	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DXZ73_RS17925	COG2205	protein histidine kinase activity
DXZ73_RS17940	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DXZ73_RS17945	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
DXZ73_RS17950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DXZ73_RS17955	COG1263	PTS System
DXZ73_RS17960	COG1263	PTS System
DXZ73_RS17965	COG1234	tRNA 3'-trailer cleavage
DXZ73_RS17985	COG1113	amino acid transport
DXZ73_RS17995	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
DXZ73_RS18005	COG1335	isochorismatase
DXZ73_RS18040	COG0277	FAD linked oxidase domain protein
DXZ73_RS18045	COG3185	4-Hydroxyphenylpyruvate dioxygenase
DXZ73_RS18055	COG1174	glycine betaine transport
DXZ73_RS18065	COG1174	glycine betaine transport
DXZ73_RS18090	COG0477	Major facilitator Superfamily
DXZ73_RS18100	COG2855	membrane
DXZ73_RS18110	COG0583	DNA-binding transcription factor activity
DXZ73_RS18155	COG1404	Belongs to the peptidase S8 family
DXZ73_RS18165	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DXZ73_RS18180	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DXZ73_RS18190	COG1678	Uncharacterized ACR, COG1678
DXZ73_RS18195	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DXZ73_RS18200	COG0776	regulation of translation
DXZ73_RS18215	COG3973	AAA domain
DXZ73_RS18215	COG3973	AAA domain
DXZ73_RS18250	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DXZ73_RS18255	COG0793	Belongs to the peptidase S41A family
DXZ73_RS18265	COG2884	Cell division ATP-binding protein ftsE
DXZ73_RS18285	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DXZ73_RS18290	COG0515	serine threonine protein kinase
DXZ73_RS18295	COG0515	serine threonine protein kinase
DXZ73_RS18305	COG1653	transport
DXZ73_RS18310	COG1175	transmembrane transport
DXZ73_RS18315	COG0395	ABC-type sugar transport system, permease component
DXZ73_RS18325	COG1215	transferase activity, transferring glycosyl groups
DXZ73_RS18335	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DXZ73_RS18350	COG0463	Glycosyl transferase, family 2
DXZ73_RS18370	COG2902	Dehydrogenase
DXZ73_RS18390	COG0653	protein targeting
DXZ73_RS18405	COG2197	response regulator
DXZ73_RS18410	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DXZ73_RS18420	COG0823	Involved in the tonB-independent uptake of proteins
DXZ73_RS18425	COG5000	phosphorelay sensor kinase activity
DXZ73_RS18425	COG5002	protein histidine kinase activity
DXZ73_RS18430	COG0745	RESPONSE REGULATOR receiver
DXZ73_RS18435	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
DXZ73_RS18475	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
DXZ73_RS18480	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DXZ73_RS18480	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DXZ73_RS18480	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DXZ73_RS18490	COG1482	cell wall glycoprotein biosynthetic process
DXZ73_RS18500	COG2835	tetraacyldisaccharide 4'-kinase activity
DXZ73_RS18505	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DXZ73_RS18545	COG0391	Required for morphogenesis under gluconeogenic growth conditions
DXZ73_RS18550	COG0778	Nitroreductase
DXZ73_RS18550	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
DXZ73_RS18580	COG1316	TRANSCRIPTIONal
DXZ73_RS18610	COG1316	TRANSCRIPTIONal
DXZ73_RS18620	COG1316	TRANSCRIPTIONal
DXZ73_RS18635	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DXZ73_RS18660	COG2205	protein histidine kinase activity
DXZ73_RS18665	COG0745	RESPONSE REGULATOR receiver
DXZ73_RS18670	COG3104	oligopeptide transport
DXZ73_RS18745	COG1366	Belongs to the anti-sigma-factor antagonist family
DXZ73_RS18750	COG1191	sigma factor activity
DXZ73_RS18755	COG0640	Transcriptional regulator
DXZ73_RS18770	COG1228	amidohydrolase
DXZ73_RS18785	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
DXZ73_RS18790	COG0019	diaminopimelate decarboxylase activity
DXZ73_RS18805	COG0318	PFAM AMP-dependent synthetase and ligase
DXZ73_RS18820	COG2755	lipolytic protein G-D-S-L family
DXZ73_RS18825	COG0183	Belongs to the thiolase family
DXZ73_RS18855	COG1136	(ABC) transporter
DXZ73_RS18860	COG0577	efflux transmembrane transporter activity
DXZ73_RS18865	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DXZ73_RS18870	COG1252	NADH dehydrogenase
DXZ73_RS18890	COG0148	phosphopyruvate hydratase activity
DXZ73_RS18905	COG2124	cytochrome p450
DXZ73_RS18925	COG2815	serine threonine protein kinase
DXZ73_RS18925	COG0515	serine threonine protein kinase
DXZ73_RS18975	COG0577	efflux transmembrane transporter activity
DXZ73_RS18980	COG1136	(ABC) transporter
DXZ73_RS19015	COG4585	Histidine kinase
DXZ73_RS19030	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DXZ73_RS19035	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DXZ73_RS19040	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DXZ73_RS19045	COG0193	aminoacyl-tRNA hydrolase activity
DXZ73_RS19050	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
DXZ73_RS19060	COG1309	transcriptional regulator
DXZ73_RS19065	COG4106	trans-aconitate 2-methyltransferase activity
DXZ73_RS19070	COG1846	Transcriptional regulator
DXZ73_RS19075	COG2197	response regulator
DXZ73_RS19080	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DXZ73_RS19095	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DXZ73_RS19120	COG0488	(ABC) transporter
DXZ73_RS19135	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DXZ73_RS19140	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DXZ73_RS19150	COG0084	hydrolase, TatD family'
DXZ73_RS19260	COG2409	Drug exporters of the RND superfamily
DXZ73_RS19270	COG4946	Tricorn protease homolog
DXZ73_RS19270	COG0793	Belongs to the peptidase S41A family
DXZ73_RS19285	COG2072	flavoprotein involved in K transport
DXZ73_RS19305	COG2205	protein histidine kinase activity
DXZ73_RS19330	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DXZ73_RS19335	COG0521	Mo-molybdopterin cofactor biosynthetic process
DXZ73_RS19335	COG0315	cyclic pyranopterin monophosphate synthase activity
DXZ73_RS19340	COG0315	cyclic pyranopterin monophosphate synthase activity
DXZ73_RS19350	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DXZ73_RS19355	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DXZ73_RS19365	COG3263	regulation of cellular component size
DXZ73_RS19380	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
DXZ73_RS19385	COG1970	mechanosensitive ion channel activity
DXZ73_RS19415	COG1131	(ABC) transporter
DXZ73_RS19420	COG1725	Transcriptional regulator
DXZ73_RS19430	COG0477	Major facilitator Superfamily
DXZ73_RS19435	COG1349	DNA-binding transcription factor activity
DXZ73_RS19445	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
DXZ73_RS19445	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DXZ73_RS19445	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DXZ73_RS19450	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DXZ73_RS19475	COG3384	dioxygenase
DXZ73_RS19480	COG1846	Transcriptional regulator
DXZ73_RS19485	COG2826	transposase and inactivated derivatives, IS30 family
DXZ73_RS19535	COG0514	ATP-dependent DNA helicase (RecQ)
DXZ73_RS19565	COG0515	serine threonine protein kinase
DXZ73_RS19575	COG1653	transport
DXZ73_RS19585	COG1686	Belongs to the peptidase S11 family
DXZ73_RS19620	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
DXZ73_RS19730	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
DXZ73_RS19740	COG1028	Short-chain dehydrogenase reductase Sdr
DXZ73_RS19785	COG1024	Enoyl-CoA hydratase
DXZ73_RS19790	COG0515	serine threonine protein kinase
DXZ73_RS19790	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DXZ73_RS19795	COG1309	transcriptional regulator
DXZ73_RS19805	COG1960	acyl-CoA dehydrogenase activity
DXZ73_RS19815	COG0259	pyridoxamine-phosphate oxidase activity
DXZ73_RS19830	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DXZ73_RS19830	COG1042	CoA-binding domain protein
DXZ73_RS19830	COG0045	succinate-CoA ligase (ADP-forming) activity
DXZ73_RS19835	COG1024	Enoyl-CoA hydratase
DXZ73_RS19840	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DXZ73_RS19870	COG1960	acyl-CoA dehydrogenase activity
DXZ73_RS19875	COG1028	Short-chain dehydrogenase reductase Sdr
DXZ73_RS19890	COG1960	acyl-CoA dehydrogenase activity
DXZ73_RS19895	COG1960	acyl-CoA dehydrogenase activity
DXZ73_RS19905	COG0318	PFAM AMP-dependent synthetase and ligase
DXZ73_RS19920	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DXZ73_RS19930	COG1077	Cell shape determining protein MreB Mrl
DXZ73_RS19935	COG0516	GMP reductase activity
DXZ73_RS19945	COG1595	DNA-templated transcription, initiation
DXZ73_RS19950	COG2197	response regulator
DXZ73_RS19960	COG0583	DNA-binding transcription factor activity
DXZ73_RS19980	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DXZ73_RS19985	COG0726	polysaccharide deacetylase
DXZ73_RS20040	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DXZ73_RS20060	COG0802	atpase or kinase
DXZ73_RS20075	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DXZ73_RS20095	COG0697	spore germination
DXZ73_RS20115	COG0736	holo-[acyl-carrier-protein] synthase activity
DXZ73_RS20120	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DXZ73_RS20130	COG1072	(Pantothenic acid kinase))
DXZ73_RS20140	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DXZ73_RS20145	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DXZ73_RS20150	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DXZ73_RS20155	COG0488	(ABC) transporter
DXZ73_RS20170	COG0438	transferase activity, transferring glycosyl groups
DXZ73_RS20175	COG0101	tRNA pseudouridine synthase activity
DXZ73_RS20180	COG0203	ribosomal protein L17
DXZ73_RS20190	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DXZ73_RS20195	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DXZ73_RS20200	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DXZ73_RS20205	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DXZ73_RS20215	COG0563	adenylate kinase activity
DXZ73_RS20225	COG0200	Binds to the 23S rRNA
DXZ73_RS20235	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DXZ73_RS20240	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DXZ73_RS20245	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DXZ73_RS20250	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DXZ73_RS20255	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DXZ73_RS20260	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DXZ73_RS20265	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DXZ73_RS20270	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DXZ73_RS20275	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DXZ73_RS20280	COG0255	Belongs to the universal ribosomal protein uL29 family
DXZ73_RS20285	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DXZ73_RS20290	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DXZ73_RS20295	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DXZ73_RS20300	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DXZ73_RS20305	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DXZ73_RS20310	COG0089	rRNA binding
DXZ73_RS20315	COG0088	Forms part of the polypeptide exit tunnel
DXZ73_RS20320	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DXZ73_RS20325	COG0051	transcription antitermination factor activity, RNA binding
DXZ73_RS20335	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DXZ73_RS20345	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DXZ73_RS20350	COG0049	tRNA binding
DXZ73_RS20355	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DXZ73_RS20360	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DXZ73_RS20365	COG0085	RNA polymerase activity
DXZ73_RS20375	COG0222	ribosome binding
DXZ73_RS20380	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DXZ73_RS20385	COG0081	regulation of translation
DXZ73_RS20390	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DXZ73_RS20395	COG0250	Participates in transcription elongation, termination and antitermination
DXZ73_RS20410	COG0436	Aminotransferase
DXZ73_RS20415	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DXZ73_RS20420	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DXZ73_RS20425	COG0477	Major facilitator Superfamily
DXZ73_RS20440	COG2030	dehydratase
DXZ73_RS20445	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DXZ73_RS20465	COG0702	epimerase
DXZ73_RS20475	COG1666	GTP binding
DXZ73_RS20480	COG3304	Inner membrane component domain
DXZ73_RS20485	COG0501	Belongs to the peptidase M48B family
DXZ73_RS20490	COG1007	ATP synthesis coupled electron transport
DXZ73_RS20505	COG0713	ATP synthesis coupled electron transport
DXZ73_RS20510	COG0839	Belongs to the complex I subunit 6 family
DXZ73_RS20515	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DXZ73_RS20520	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DXZ73_RS20525	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DXZ73_RS20530	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DXZ73_RS20535	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DXZ73_RS20545	COG4585	Histidine kinase
DXZ73_RS20555	COG0674	pyruvate-flavodoxin oxidoreductase activity
DXZ73_RS20555	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DXZ73_RS20560	COG1013	pyruvate-flavodoxin oxidoreductase activity
DXZ73_RS20565	COG0531	amino acid
DXZ73_RS20575	COG4935	Belongs to the peptidase S8 family
DXZ73_RS20575	COG2234	aminopeptidase activity
DXZ73_RS20595	COG0142	geranyltranstransferase activity
DXZ73_RS20600	COG0492	ferredoxin-NADP+ reductase activity
DXZ73_RS20620	COG1007	ATP synthesis coupled electron transport
DXZ73_RS20630	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DXZ73_RS20635	COG0713	ATP synthesis coupled electron transport
DXZ73_RS20640	COG0839	Belongs to the complex I subunit 6 family
DXZ73_RS20645	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DXZ73_RS20650	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DXZ73_RS20655	COG1034	ATP synthesis coupled electron transport
DXZ73_RS20660	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
DXZ73_RS20670	COG0649	NAD binding
DXZ73_RS20675	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DXZ73_RS20680	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DXZ73_RS20700	COG2226	methyltransferase
DXZ73_RS20710	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
DXZ73_RS20715	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DXZ73_RS20715	COG0515	serine threonine protein kinase
DXZ73_RS20720	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
DXZ73_RS20725	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
DXZ73_RS20730	COG1278	Cold shock
DXZ73_RS20760	COG1301	dicarboxylic acid transport
DXZ73_RS20775	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
DXZ73_RS20785	COG0163	prenyltransferase activity
DXZ73_RS20790	COG0109	protoheme IX farnesyltransferase activity
DXZ73_RS20795	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
DXZ73_RS20810	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DXZ73_RS20815	COG1333	cytochrome c biogenesis protein
DXZ73_RS20820	COG0785	Cytochrome C biogenesis protein
DXZ73_RS20835	COG0406	alpha-ribazole phosphatase activity
DXZ73_RS20840	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DXZ73_RS20845	COG0494	nUDIX hydrolase
DXZ73_RS20875	COG3629	intracellular signal transduction
DXZ73_RS20875	COG3903	Transcriptional regulator
DXZ73_RS20935	COG1742	UPF0060 membrane protein
DXZ73_RS20950	COG1690	Belongs to the RtcB family
DXZ73_RS20965	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
DXZ73_RS20970	COG0018	arginyl-trna synthetase
DXZ73_RS20980	COG0113	porphobilinogen synthase activity
DXZ73_RS20985	COG1648	precorrin-2 dehydrogenase activity
DXZ73_RS20985	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DXZ73_RS20990	COG0181	hydroxymethylbilane synthase activity
DXZ73_RS20995	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DXZ73_RS21000	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DXZ73_RS21050	COG0123	including yeast histone deacetylase and acetoin utilization protein
DXZ73_RS21060	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DXZ73_RS21080	COG0180	Tryptophanyl-tRNA synthetase
DXZ73_RS21085	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DXZ73_RS21115	COG1846	Transcriptional regulator
DXZ73_RS21130	COG1252	NADH dehydrogenase
DXZ73_RS21140	COG1470	cell adhesion involved in biofilm formation
DXZ73_RS21140	COG0366	Alpha amylase catalytic
DXZ73_RS21155	COG0579	oxidoreductase
DXZ73_RS21190	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DXZ73_RS21205	COG0270	DNA (cytosine-5-)-methyltransferase activity
DXZ73_RS21240	COG0667	Aldo Keto reductase
DXZ73_RS21245	COG2814	Major facilitator Superfamily
DXZ73_RS21265	COG1278	Cold shock
DXZ73_RS21280	COG0513	Belongs to the DEAD box helicase family
DXZ73_RS21310	COG1643	Atp-dependent helicase
DXZ73_RS21345	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DXZ73_RS21360	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DXZ73_RS21365	COG0047	phosphoribosylformylglycinamidine synthase activity
DXZ73_RS21370	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DXZ73_RS21430	COG0745	RESPONSE REGULATOR receiver
DXZ73_RS21440	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DXZ73_RS21445	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DXZ73_RS21460	COG0151	Belongs to the GarS family
DXZ73_RS21475	COG0463	Glycosyl transferase, family 2
DXZ73_RS21480	COG1802	Transcriptional regulator
DXZ73_RS21485	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DXZ73_RS21490	COG1278	Cold shock
DXZ73_RS21495	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DXZ73_RS21495	COG0515	serine threonine protein kinase
DXZ73_RS21500	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DXZ73_RS21510	COG2197	response regulator
DXZ73_RS21515	COG4585	Histidine kinase
DXZ73_RS21525	COG3844	kynureninase activity
DXZ73_RS21530	COG3483	tryptophan 2,3-dioxygenase activity
DXZ73_RS21540	COG0477	Major facilitator Superfamily
DXZ73_RS21545	COG0191	fructose-bisphosphate aldolase activity
DXZ73_RS21550	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DXZ73_RS21565	COG2910	NAD(P)H-binding
DXZ73_RS21580	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DXZ73_RS21600	COG0542	response to heat
DXZ73_RS21615	COG0789	Transcriptional regulator
DXZ73_RS21620	COG0484	heat shock protein binding
DXZ73_RS21625	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DXZ73_RS21630	COG0443	Heat shock 70 kDa protein
DXZ73_RS21635	COG2181	nitrate reductase activity
DXZ73_RS21635	COG0247	lactate metabolic process
DXZ73_RS21645	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
DXZ73_RS21650	COG0717	Belongs to the dCTP deaminase family
DXZ73_RS21745	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DXZ73_RS21775	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
DXZ73_RS21795	COG2205	protein histidine kinase activity
DXZ73_RS21800	COG0745	RESPONSE REGULATOR receiver
DXZ73_RS21820	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DXZ73_RS21830	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DXZ73_RS21840	COG1741	Belongs to the pirin family
DXZ73_RS21855	COG1960	acyl-CoA dehydrogenase activity
DXZ73_RS21860	COG1362	aminopeptidase activity
DXZ73_RS21865	COG3629	intracellular signal transduction
DXZ73_RS21865	COG3903	Transcriptional regulator
DXZ73_RS21880	COG2963	transposase activity
DXZ73_RS21900	COG2271	Major facilitator Superfamily
DXZ73_RS21915	COG0508	dehydrogenase complex catalyzes the overall conversion of
DXZ73_RS21920	COG0022	dehydrogenase e1 component
DXZ73_RS21945	COG0515	serine threonine protein kinase
DXZ73_RS21950	COG0515	serine threonine protein kinase
DXZ73_RS21965	COG0604	alcohol dehydrogenase
DXZ73_RS21975	COG0303	'Molybdopterin
DXZ73_RS21980	COG0746	molybdenum cofactor guanylyltransferase activity
DXZ73_RS22000	COG1522	sequence-specific DNA binding
DXZ73_RS22005	COG1309	transcriptional regulator
DXZ73_RS22010	COG1250	3-hydroxyacyl-CoA dehydrogenase
DXZ73_RS22035	COG3396	Phenylacetate-CoA oxygenase
DXZ73_RS22040	COG3460	Phenylacetate-CoA oxygenase
DXZ73_RS22045	COG3396	Phenylacetate-CoA oxygenase
DXZ73_RS22050	COG2151	metal-sulfur cluster biosynthetic enzyme
DXZ73_RS22055	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DXZ73_RS22065	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DXZ73_RS22080	COG1733	regulation of RNA biosynthetic process
DXZ73_RS22085	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DXZ73_RS22105	COG1716	ATPase activity
DXZ73_RS22110	COG1716	ATPase activity
DXZ73_RS22120	COG0772	Belongs to the SEDS family
DXZ73_RS22125	COG0768	penicillin binding
DXZ73_RS22130	COG0515	serine threonine protein kinase
DXZ73_RS22135	COG3764	Sortase (surface protein transpeptidase)
DXZ73_RS22140	COG3764	Sortase (surface protein transpeptidase)
DXZ73_RS22150	COG3764	Sortase (surface protein transpeptidase)
DXZ73_RS22165	COG0705	Rhomboid family
DXZ73_RS22190	COG0515	serine threonine protein kinase
DXZ73_RS22210	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DXZ73_RS22220	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
DXZ73_RS22225	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DXZ73_RS22230	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
DXZ73_RS22235	COG0592	DNA-directed DNA polymerase activity
DXZ73_RS22250	COG0230	Belongs to the bacterial ribosomal protein bL34 family
DXZ73_RS22255	COG0594	ribonuclease P activity
DXZ73_RS22260	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DXZ73_RS22265	COG0706	membrane insertase activity
DXZ73_RS22275	COG0357	Ribosomal RNA small subunit methyltransferase G
DXZ73_RS22280	COG1192	Involved in chromosome partitioning
DXZ73_RS22295	COG3118	belongs to the thioredoxin family
DXZ73_RS22300	COG0492	ferredoxin-NADP+ reductase activity
DXZ73_RS22310	COG1595	DNA-templated transcription, initiation
DXZ73_RS22315	COG2815	serine threonine protein kinase
DXZ73_RS22315	COG0515	serine threonine protein kinase
DXZ73_RS22330	COG0617	tRNA 3'-terminal CCA addition
DXZ73_RS22340	COG1260	myo-inositol-1-phosphate synthase
DXZ73_RS22350	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DXZ73_RS22375	COG0360	Binds together with S18 to 16S ribosomal RNA
DXZ73_RS22380	COG0629	single-stranded DNA binding
DXZ73_RS22385	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DXZ73_RS22390	COG0359	binds to the 23S rRNA
DXZ73_RS22405	COG0305	Participates in initiation and elongation during chromosome replication
DXZ73_RS22440	COG2814	Major facilitator Superfamily
DXZ73_RS22475	COG0626	cystathionine gamma-synthase activity
DXZ73_RS22480	COG1950	PFAM Membrane protein of
DXZ73_RS22485	COG0662	Cupin 2, conserved barrel domain protein
DXZ73_RS22500	COG2268	Band 7 protein
DXZ73_RS22515	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DXZ73_RS22530	COG1609	Transcriptional regulator
DXZ73_RS22535	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DXZ73_RS22540	COG1271	oxidase subunit
DXZ73_RS22545	COG1294	oxidase, subunit
DXZ73_RS22550	COG4988	ABC transporter
DXZ73_RS22560	COG0739	heme binding
DXZ73_RS22565	COG0561	phosphatase activity
DXZ73_RS22575	COG0501	Belongs to the peptidase M48B family
DXZ73_RS22615	COG1131	(ABC) transporter
DXZ73_RS22635	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
DXZ73_RS22640	COG2807	transmembrane transport
DXZ73_RS22645	COG2188	Transcriptional regulator
DXZ73_RS22655	COG0561	phosphatase activity
DXZ73_RS22660	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DXZ73_RS22675	COG2837	iron assimilation
DXZ73_RS22680	COG2372	response to copper ion
DXZ73_RS22690	COG1999	signal sequence binding
DXZ73_RS22715	COG0006	proline dipeptidase activity
DXZ73_RS22735	COG0653	protein targeting
DXZ73_RS22750	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DXZ73_RS22760	COG0596	Alpha beta hydrolase
DXZ73_RS22765	COG1309	transcriptional regulator
DXZ73_RS22810	COG1595	DNA-templated transcription, initiation
DXZ73_RS22830	COG1388	LysM domain
DXZ73_RS22830	COG1705	Flagellar rod assembly protein muramidase FlgJ
DXZ73_RS22840	COG0318	PFAM AMP-dependent synthetase and ligase
DXZ73_RS22960	COG0745	RESPONSE REGULATOR receiver
DXZ73_RS22965	COG2205	protein histidine kinase activity
DXZ73_RS22975	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DXZ73_RS22980	COG0477	Major facilitator Superfamily
DXZ73_RS23010	COG1191	sigma factor activity
DXZ73_RS23015	COG1191	sigma factor activity
DXZ73_RS23045	COG1028	Short-chain dehydrogenase reductase Sdr
DXZ73_RS23055	COG0477	Major facilitator Superfamily
DXZ73_RS23060	COG0640	Transcriptional regulator
DXZ73_RS23080	COG4948	Mandelate Racemase Muconate Lactonizing
DXZ73_RS23095	COG0667	Aldo Keto reductase
DXZ73_RS23110	COG1309	transcriptional regulator
DXZ73_RS23140	COG1280	lysine exporter protein (LysE YggA)
DXZ73_RS23145	COG0300	oxidoreductase activity
DXZ73_RS23165	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DXZ73_RS23185	COG0583	DNA-binding transcription factor activity
DXZ73_RS23210	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DXZ73_RS23265	COG2313	pseudouridylate synthase activity
DXZ73_RS23290	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DXZ73_RS23330	COG0697	spore germination
DXZ73_RS23375	COG2197	response regulator
DXZ73_RS23385	COG1178	ABC-type Fe3 transport system permease component
DXZ73_RS23390	COG3842	ATPase activity
DXZ73_RS23400	COG2130	NADP-dependent
DXZ73_RS23405	COG2249	NAD(P)H dehydrogenase (quinone) activity
DXZ73_RS23415	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DXZ73_RS23450	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DXZ73_RS23455	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DXZ73_RS23480	COG1595	DNA-templated transcription, initiation
DXZ73_RS23510	COG2814	Major facilitator Superfamily
DXZ73_RS23545	COG2770	Histidine kinase
DXZ73_RS23545	COG2208	phosphoserine phosphatase activity
DXZ73_RS23565	COG2201	protein-glutamate methylesterase activity
DXZ73_RS23605	COG1408	metallophosphoesterase
DXZ73_RS23615	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DXZ73_RS23630	COG0003	Pfam Anion-transporting ATPase
DXZ73_RS23685	COG0596	Alpha beta hydrolase
DXZ73_RS23695	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DXZ73_RS23700	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DXZ73_RS23705	COG0659	secondary active sulfate transmembrane transporter activity
DXZ73_RS23760	COG1205	dead DEAH box helicase
DXZ73_RS23760	COG1111	helicase
DXZ73_RS23765	COG1366	Belongs to the anti-sigma-factor antagonist family
DXZ73_RS23770	COG2172	sigma factor antagonist activity
DXZ73_RS23775	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
DXZ73_RS23785	COG2890	protein-(glutamine-N5) methyltransferase activity
DXZ73_RS23790	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DXZ73_RS23790	COG1754	DNA topoisomerase type I activity
DXZ73_RS23795	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DXZ73_RS23800	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DXZ73_RS23820	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
DXZ73_RS23830	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
DXZ73_RS23835	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
DXZ73_RS23850	COG3958	Transketolase
DXZ73_RS23855	COG3959	Transketolase, thiamine diphosphate binding domain
DXZ73_RS23860	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DXZ73_RS23865	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DXZ73_RS23870	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DXZ73_RS23875	COG0189	ligase activity
DXZ73_RS23890	COG2046	Belongs to the sulfate adenylyltransferase family
DXZ73_RS23890	COG0529	Catalyzes the synthesis of activated sulfate
DXZ73_RS23925	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DXZ73_RS23955	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DXZ73_RS23965	COG1960	acyl-CoA dehydrogenase activity
DXZ73_RS24005	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DXZ73_RS24020	COG0747	negative chemotaxis
DXZ73_RS24030	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DXZ73_RS24040	COG0583	DNA-binding transcription factor activity
DXZ73_RS24080	COG1181	Belongs to the D-alanine--D-alanine ligase family
DXZ73_RS24110	COG1077	Cell shape determining protein MreB Mrl
DXZ73_RS24145	COG2188	Transcriptional regulator
DXZ73_RS24150	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DXZ73_RS24190	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DXZ73_RS24195	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DXZ73_RS24200	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DXZ73_RS24205	COG0254	rRNA binding
DXZ73_RS24215	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DXZ73_RS24235	COG1012	belongs to the aldehyde dehydrogenase family
DXZ73_RS24240	COG2318	DinB family
DXZ73_RS24250	COG0076	glutamate decarboxylase activity
DXZ73_RS24255	COG0393	Putative heavy-metal-binding
DXZ73_RS24270	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DXZ73_RS24275	COG2027	D-alanyl-D-alanine carboxypeptidase
DXZ73_RS24285	COG0037	tRNA processing
DXZ73_RS24300	COG0302	gtp cyclohydrolase
DXZ73_RS24315	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DXZ73_RS24325	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DXZ73_RS24330	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DXZ73_RS24340	COG0517	IMP dehydrogenase activity
DXZ73_RS24340	COG1125	glycine betaine transport
DXZ73_RS24345	COG1174	glycine betaine transport
DXZ73_RS24355	COG1732	Glycine betaine
DXZ73_RS24365	COG0649	NAD binding
DXZ73_RS24380	COG2197	response regulator
DXZ73_RS24385	COG0583	DNA-binding transcription factor activity
DXZ73_RS24395	COG0640	Transcriptional regulator
DXZ73_RS24415	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DXZ73_RS24420	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DXZ73_RS24430	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DXZ73_RS24450	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
DXZ73_RS24480	COG1196	nuclear chromosome segregation
DXZ73_RS24480	COG0741	lytic transglycosylase activity
DXZ73_RS24480	COG0739	heme binding
DXZ73_RS24490	COG0346	lactoylglutathione lyase activity
DXZ73_RS24495	COG2205	protein histidine kinase activity
DXZ73_RS24500	COG0745	RESPONSE REGULATOR receiver
DXZ73_RS24510	COG1595	DNA-templated transcription, initiation
DXZ73_RS24520	COG4585	Histidine kinase
DXZ73_RS24525	COG2197	response regulator
DXZ73_RS24535	COG0671	phosphoesterase, PA-phosphatase related
DXZ73_RS24545	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
DXZ73_RS24565	COG0248	Ppx GppA phosphatase
DXZ73_RS24570	COG1082	Xylose isomerase domain protein TIM barrel
DXZ73_RS24580	COG0129	dihydroxy-acid dehydratase activity
DXZ73_RS24585	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DXZ73_RS24585	COG0515	serine threonine protein kinase
DXZ73_RS24590	COG4991	sh3 domain protein
DXZ73_RS24625	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DXZ73_RS24665	COG2815	serine threonine protein kinase
DXZ73_RS24665	COG0515	serine threonine protein kinase
DXZ73_RS24685	COG3209	COG3209 Rhs family protein
DXZ73_RS24725	COG0741	lytic transglycosylase activity
DXZ73_RS24725	COG0739	heme binding
DXZ73_RS24725	COG1196	nuclear chromosome segregation
DXZ73_RS24730	COG0671	phosphoesterase, PA-phosphatase related
DXZ73_RS24745	COG1937	Protein conserved in bacteria
DXZ73_RS24760	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DXZ73_RS24835	COG0657	acetylesterase activity
DXZ73_RS24840	COG1595	DNA-templated transcription, initiation
DXZ73_RS24855	COG1090	epimerase
DXZ73_RS24865	COG2890	protein-(glutamine-N5) methyltransferase activity
DXZ73_RS24875	COG0431	NADPH-dependent FMN reductase
DXZ73_RS24880	COG4552	Acetyltransferase involved in intracellular survival and related
DXZ73_RS24895	COG1490	D-aminoacyl-tRNA deacylase activity
DXZ73_RS24910	COG4607	ABC-type enterochelin transport system periplasmic component
DXZ73_RS24915	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
DXZ73_RS24920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DXZ73_RS24925	COG3485	protocatechuate 3,4-dioxygenase
DXZ73_RS24945	COG2897	thiosulfate sulfurtransferase activity
DXZ73_RS24975	COG0745	RESPONSE REGULATOR receiver
DXZ73_RS24980	COG1609	Transcriptional regulator
DXZ73_RS24995	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DXZ73_RS25075	COG1113	amino acid transport
DXZ73_RS25085	COG2304	oxidoreductase activity
DXZ73_RS25120	COG0745	RESPONSE REGULATOR receiver
DXZ73_RS25125	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DXZ73_RS25135	COG0737	Belongs to the 5'-nucleotidase family
DXZ73_RS25140	COG0456	acetyltransferase
DXZ73_RS25145	COG1725	Transcriptional regulator
DXZ73_RS25150	COG1131	(ABC) transporter
DXZ73_RS25155	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DXZ73_RS25175	COG0438	transferase activity, transferring glycosyl groups
DXZ73_RS25190	COG0588	phosphoglycerate mutase activity
DXZ73_RS25210	COG5002	protein histidine kinase activity
DXZ73_RS25230	COG1329	Transcriptional regulator
DXZ73_RS25235	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DXZ73_RS25240	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DXZ73_RS25255	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DXZ73_RS25260	COG0215	cysteine-tRNA ligase activity
DXZ73_RS25275	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DXZ73_RS25285	COG3842	ATPase activity
DXZ73_RS25295	COG2409	Drug exporters of the RND superfamily
DXZ73_RS25355	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DXZ73_RS25360	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DXZ73_RS25375	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DXZ73_RS25435	COG0191	fructose-bisphosphate aldolase activity
DXZ73_RS25455	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DXZ73_RS25485	COG0463	Glycosyl transferase, family 2
DXZ73_RS25515	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
DXZ73_RS25520	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
DXZ73_RS25545	COG3973	AAA domain
DXZ73_RS25550	COG1061	Type III restriction enzyme res subunit
DXZ73_RS25565	COG1120	ATPase activity
DXZ73_RS25570	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DXZ73_RS25575	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DXZ73_RS25580	COG0546	phosphoglycolate phosphatase activity
DXZ73_RS25590	COG1278	Cold shock
DXZ73_RS25595	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
DXZ73_RS25600	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DXZ73_RS25610	COG2814	Major facilitator Superfamily
DXZ73_RS25630	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DXZ73_RS25640	COG2252	PERMEase
DXZ73_RS25650	COG2814	Major facilitator Superfamily
DXZ73_RS25660	COG0667	Aldo Keto reductase
DXZ73_RS25730	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DXZ73_RS25735	COG0247	lactate metabolic process
DXZ73_RS25735	COG0277	FAD linked oxidase domain protein
DXZ73_RS25745	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DXZ73_RS25760	COG1024	Enoyl-CoA hydratase
DXZ73_RS25775	COG0259	pyridoxamine-phosphate oxidase activity
DXZ73_RS25785	COG4821	SIS domain
DXZ73_RS25795	COG0596	Alpha beta hydrolase
DXZ73_RS25800	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DXZ73_RS25845	COG1366	Belongs to the anti-sigma-factor antagonist family
DXZ73_RS25855	COG2197	response regulator
DXZ73_RS25890	COG1309	transcriptional regulator
DXZ73_RS25910	COG1309	transcriptional regulator
DXZ73_RS25940	COG0515	serine threonine protein kinase
DXZ73_RS25940	COG2815	serine threonine protein kinase
DXZ73_RS25945	COG1012	belongs to the aldehyde dehydrogenase family
DXZ73_RS25960	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DXZ73_RS25960	COG0519	Catalyzes the synthesis of GMP from XMP
DXZ73_RS25975	COG1376	ErfK ybiS ycfS ynhG family protein
DXZ73_RS25995	COG0515	serine threonine protein kinase
DXZ73_RS25995	COG2815	serine threonine protein kinase
DXZ73_RS26005	COG2197	response regulator
DXZ73_RS26015	COG0791	NLP P60 protein
DXZ73_RS26030	COG0739	heme binding
DXZ73_RS26040	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DXZ73_RS26055	COG0714	Associated with various cellular activities
DXZ73_RS26060	COG3552	Protein containing von Willebrand factor type A (VWA) domain
DXZ73_RS26065	COG0045	succinate-CoA ligase (ADP-forming) activity
DXZ73_RS26090	COG0138	bifunctional purine biosynthesis protein purh
DXZ73_RS26100	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DXZ73_RS26110	COG0538	isocitrate dehydrogenase activity
DXZ73_RS26120	COG0039	L-malate dehydrogenase activity
DXZ73_RS26140	COG1012	belongs to the aldehyde dehydrogenase family
DXZ73_RS26150	COG0517	IMP dehydrogenase activity
DXZ73_RS26150	COG4175	Glycine betaine
DXZ73_RS26155	COG4176	ABC-type proline glycine betaine transport system permease component
DXZ73_RS26165	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DXZ73_RS26170	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DXZ73_RS26185	COG0754	glutathionylspermidine amidase activity
DXZ73_RS26190	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DXZ73_RS26195	COG0180	Tryptophanyl-tRNA synthetase
DXZ73_RS26205	COG1295	ribonuclease BN
DXZ73_RS26215	COG4166	transmembrane transport
DXZ73_RS26230	COG1053	succinate dehydrogenase
DXZ73_RS26240	COG2009	succinate dehydrogenase
DXZ73_RS26265	COG1595	DNA-templated transcription, initiation
DXZ73_RS26275	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DXZ73_RS26275	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DXZ73_RS26385	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DXZ73_RS26400	COG2186	Transcriptional regulator
DXZ73_RS26405	COG3265	gluconokinase activity
DXZ73_RS26480	COG0328	RNA-DNA hybrid ribonuclease activity
DXZ73_RS26490	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DXZ73_RS26505	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DXZ73_RS26515	COG1216	Glycosyl transferase, family 2
DXZ73_RS26530	COG2089	acid synthase
DXZ73_RS26540	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
DXZ73_RS26540	COG1473	amidohydrolase
DXZ73_RS26545	COG1744	ABC transporter substrate-binding protein PnrA-like
DXZ73_RS26550	COG3845	ABC transporter
DXZ73_RS26555	COG4603	Belongs to the binding-protein-dependent transport system permease family
DXZ73_RS26560	COG1079	Belongs to the binding-protein-dependent transport system permease family
DXZ73_RS26580	COG2814	Major facilitator Superfamily
DXZ73_RS26585	COG0583	DNA-binding transcription factor activity
DXZ73_RS26595	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DXZ73_RS26620	COG2205	protein histidine kinase activity
DXZ73_RS26625	COG0745	RESPONSE REGULATOR receiver
DXZ73_RS26630	COG1595	DNA-templated transcription, initiation
DXZ73_RS26645	COG1012	belongs to the aldehyde dehydrogenase family
DXZ73_RS26650	COG1012	belongs to the aldehyde dehydrogenase family
DXZ73_RS26655	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DXZ73_RS26665	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DXZ73_RS26695	COG4770	biotin carboxylase activity
DXZ73_RS26700	COG1414	Transcriptional regulator
DXZ73_RS26705	COG0693	protein deglycase activity
DXZ73_RS26715	COG0424	maF-like protein
DXZ73_RS26720	COG0768	penicillin binding
DXZ73_RS26730	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DXZ73_RS26740	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
DXZ73_RS26745	COG1024	Enoyl-CoA hydratase
DXZ73_RS26755	COG2986	histidine ammonia-lyase
DXZ73_RS26785	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DXZ73_RS26795	COG0740	serine-type endopeptidase activity
DXZ73_RS26800	COG0740	serine-type endopeptidase activity
DXZ73_RS26805	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DXZ73_RS26835	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DXZ73_RS26850	COG2826	transposase and inactivated derivatives, IS30 family
DXZ73_RS26855	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DXZ73_RS26865	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DXZ73_RS26875	COG2255	four-way junction helicase activity
DXZ73_RS26880	COG1331	Highly conserved protein containing a thioredoxin domain
DXZ73_RS26890	COG0477	Major facilitator Superfamily
DXZ73_RS26900	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
DXZ73_RS26955	COG1414	Transcriptional regulator
DXZ73_RS26995	COG2894	cell division
DXZ73_RS27035	COG2885	chlorophyll binding
DXZ73_RS27065	COG0667	Aldo Keto reductase
DXZ73_RS27070	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DXZ73_RS27075	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
DXZ73_RS27095	COG2755	lipolytic protein G-D-S-L family
DXZ73_RS27105	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DXZ73_RS27110	COG0450	alkyl hydroperoxide reductase
DXZ73_RS27130	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DXZ73_RS27155	COG0114	fumarate hydratase activity
DXZ73_RS27165	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
DXZ73_RS27165	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
DXZ73_RS27190	COG0778	Nitroreductase
DXZ73_RS27195	COG1722	exodeoxyribonuclease VII activity
DXZ73_RS27200	COG1570	exodeoxyribonuclease VII activity
DXZ73_RS27210	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DXZ73_RS27225	COG0012	GTP binding
DXZ73_RS27230	COG2161	toxin-antitoxin pair type II binding
DXZ73_RS27235	COG4115	mRNA cleavage
DXZ73_RS27275	COG0531	amino acid
DXZ73_RS27330	COG1217	gtp-binding protein TYPA
DXZ73_RS27345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DXZ73_RS27350	COG0444	Belongs to the ABC transporter superfamily
DXZ73_RS27355	COG4608	Belongs to the ABC transporter superfamily
DXZ73_RS27360	COG4166	transmembrane transport
DXZ73_RS27365	COG0601	transmembrane transport
DXZ73_RS27370	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DXZ73_RS27380	COG4608	Belongs to the ABC transporter superfamily
DXZ73_RS27385	COG4608	Belongs to the ABC transporter superfamily
DXZ73_RS27390	COG0444	Belongs to the ABC transporter superfamily
DXZ73_RS27400	COG4166	transmembrane transport
DXZ73_RS27405	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DXZ73_RS27420	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DXZ73_RS27440	COG1131	(ABC) transporter
DXZ73_RS27450	COG4585	Histidine kinase
DXZ73_RS27455	COG2197	response regulator
DXZ73_RS27495	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DXZ73_RS27505	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DXZ73_RS27515	COG0519	Catalyzes the synthesis of GMP from XMP
DXZ73_RS27520	COG1024	Enoyl-CoA hydratase
DXZ73_RS27535	COG1595	DNA-templated transcription, initiation
DXZ73_RS27545	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DXZ73_RS27550	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DXZ73_RS27560	COG3422	double-strand break repair
DXZ73_RS27595	COG0598	Magnesium transport protein CorA
DXZ73_RS27615	COG2095	MarC family integral membrane protein
DXZ73_RS27620	COG1432	Conserved Protein
DXZ73_RS27635	COG0513	Belongs to the DEAD box helicase family
DXZ73_RS27680	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DXZ73_RS27685	COG0601	transmembrane transport
DXZ73_RS27690	COG4172	Belongs to the ABC transporter superfamily
DXZ73_RS27695	COG0297	glycogen (starch) synthase activity
DXZ73_RS27770	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DXZ73_RS27810	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DXZ73_RS27865	COG3480	Lon protease (S16) C-terminal proteolytic domain
DXZ73_RS27875	COG1615	UPF0182 protein
DXZ73_RS27900	COG0753	catalase activity
DXZ73_RS27910	COG0483	inositol monophosphate 1-phosphatase activity
DXZ73_RS27940	COG2076	Multidrug Resistance protein
DXZ73_RS27950	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DXZ73_RS27960	COG2135	peptidase activity
DXZ73_RS27970	COG1595	DNA-templated transcription, initiation
DXZ73_RS27975	COG5662	AntiSigma factor
DXZ73_RS27980	COG2199	diguanylate cyclase activity
DXZ73_RS27980	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
DXZ73_RS27995	COG0242	peptide deformylase activity
DXZ73_RS28000	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DXZ73_RS28040	COG0494	nUDIX hydrolase
DXZ73_RS28095	COG2188	Transcriptional regulator
DXZ73_RS28100	COG2182	Extracellular solute-binding protein
DXZ73_RS28105	COG1175	transmembrane transport
DXZ73_RS28110	COG0395	ABC-type sugar transport system, permease component
DXZ73_RS28115	COG1472	Belongs to the glycosyl hydrolase 3 family
DXZ73_RS28120	COG0363	glucosamine-6-phosphate deaminase activity
DXZ73_RS28135	COG1597	lipid kinase activity
DXZ73_RS28180	COG2066	Belongs to the glutaminase family
DXZ73_RS28190	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DXZ73_RS28220	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DXZ73_RS28225	COG0640	Transcriptional regulator
DXZ73_RS28230	COG1191	sigma factor activity
DXZ73_RS28255	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DXZ73_RS28275	COG1126	abc transporter atp-binding protein
DXZ73_RS28280	COG0765	amino acid transport
DXZ73_RS28290	COG0281	malic enzyme
DXZ73_RS28295	COG0604	alcohol dehydrogenase
DXZ73_RS28330	COG2255	four-way junction helicase activity
DXZ73_RS28355	COG0567	Dehydrogenase, E1 component
DXZ73_RS28355	COG0508	dehydrogenase complex catalyzes the overall conversion of
DXZ73_RS28360	COG2205	protein histidine kinase activity
DXZ73_RS28365	COG0745	RESPONSE REGULATOR receiver
DXZ73_RS28380	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DXZ73_RS28465	COG2010	Cytochrome c
DXZ73_RS28465	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DXZ73_RS28480	COG3227	Zinc metalloprotease (Elastase)
DXZ73_RS28525	COG0791	NLP P60 protein
DXZ73_RS28525	COG3883	PFAM NLP P60 protein
DXZ73_RS28570	COG0745	RESPONSE REGULATOR receiver
DXZ73_RS28575	COG0018	arginyl-trna synthetase
DXZ73_RS28580	COG0019	diaminopimelate decarboxylase activity
DXZ73_RS28585	COG0460	homoserine dehydrogenase
DXZ73_RS28590	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DXZ73_RS28595	COG0083	homoserine kinase activity
DXZ73_RS28605	COG1316	TRANSCRIPTIONal
DXZ73_RS28610	COG0254	rRNA binding
DXZ73_RS28615	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DXZ73_RS28620	COG2890	protein-(glutamine-N5) methyltransferase activity
DXZ73_RS28630	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DXZ73_RS28635	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DXZ73_RS28640	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DXZ73_RS28655	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DXZ73_RS28660	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DXZ73_RS28665	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DXZ73_RS28670	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DXZ73_RS28675	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DXZ73_RS28680	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DXZ73_RS28685	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DXZ73_RS28700	COG2197	response regulator
DXZ73_RS28705	COG4585	Histidine kinase
DXZ73_RS28720	COG1250	3-hydroxyacyl-CoA dehydrogenase
DXZ73_RS28735	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
DXZ73_RS28795	COG0183	Belongs to the thiolase family
DXZ73_RS28810	COG1113	amino acid transport
DXZ73_RS28815	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DXZ73_RS28820	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DXZ73_RS28825	COG0596	Alpha beta hydrolase
DXZ73_RS28830	COG0789	Transcriptional regulator
DXZ73_RS28875	COG0789	Transcriptional regulator
DXZ73_RS28880	COG2814	Major facilitator Superfamily
DXZ73_RS28980	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DXZ73_RS28980	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DXZ73_RS29020	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DXZ73_RS29025	COG0280	phosphate acetyltransferase
DXZ73_RS29025	COG0857	belongs to the CobB CobQ family
DXZ73_RS29030	COG0205	6-phosphofructokinase activity
DXZ73_RS29090	COG1028	Short-chain dehydrogenase reductase Sdr
DXZ73_RS29095	COG1028	Short-chain dehydrogenase reductase Sdr
DXZ73_RS29110	COG2814	Major facilitator Superfamily
DXZ73_RS29120	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DXZ73_RS29135	COG1309	transcriptional regulator
DXZ73_RS29145	COG0395	ABC-type sugar transport system, permease component
DXZ73_RS29155	COG1136	(ABC) transporter
DXZ73_RS29160	COG0577	efflux transmembrane transporter activity
DXZ73_RS29160	COG1136	(ABC) transporter
DXZ73_RS29165	COG0477	Major facilitator Superfamily
DXZ73_RS29200	COG1720	tRNA m6t6A37 methyltransferase activity
DXZ73_RS29215	COG1301	dicarboxylic acid transport
DXZ73_RS29220	COG3290	protein histidine kinase activity
DXZ73_RS29225	COG4565	transcriptional regulatory protein
DXZ73_RS29235	COG1175	transmembrane transport
DXZ73_RS29240	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
DXZ73_RS29245	COG0657	acetylesterase activity
DXZ73_RS29255	COG0477	Major facilitator Superfamily
DXZ73_RS29260	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DXZ73_RS29270	COG0366	Alpha amylase catalytic
DXZ73_RS29275	COG0366	Alpha amylase catalytic
DXZ73_RS29285	COG0058	SHG alpha-glucan phosphorylase activity
DXZ73_RS29295	COG1132	(ABC) transporter
DXZ73_RS29300	COG1132	(ABC) transporter
DXZ73_RS29345	COG1760	l-serine dehydratase
DXZ73_RS29350	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DXZ73_RS29355	COG0509	glycine decarboxylation via glycine cleavage system
DXZ73_RS29360	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DXZ73_RS29385	COG0747	negative chemotaxis
DXZ73_RS29390	COG0601	transmembrane transport
DXZ73_RS29395	COG0444	Belongs to the ABC transporter superfamily
DXZ73_RS29400	COG4608	Belongs to the ABC transporter superfamily
DXZ73_RS29405	COG2860	membrane
DXZ73_RS29420	COG0482	sulfurtransferase activity
DXZ73_RS29435	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DXZ73_RS29445	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DXZ73_RS29450	COG0154	amidase activity
DXZ73_RS29460	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DXZ73_RS29470	COG2409	Drug exporters of the RND superfamily
DXZ73_RS29475	COG2133	pyrroloquinoline quinone binding
DXZ73_RS29480	COG0667	Aldo Keto reductase
DXZ73_RS29490	COG3300	MHYT domain
DXZ73_RS29490	COG5001	Diguanylate cyclase
DXZ73_RS29500	COG0440	acetolactate synthase activity
DXZ73_RS29505	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DXZ73_RS29510	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DXZ73_RS29520	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DXZ73_RS29525	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DXZ73_RS29535	COG1309	transcriptional regulator
DXZ73_RS29545	COG2124	cytochrome p450
DXZ73_RS29560	COG0506	proline dehydrogenase activity
DXZ73_RS29565	COG1012	belongs to the aldehyde dehydrogenase family
DXZ73_RS29575	COG0473	3-isopropylmalate dehydrogenase activity
DXZ73_RS29580	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DXZ73_RS29585	COG0477	Major facilitator Superfamily
DXZ73_RS29595	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DXZ73_RS29615	COG5492	domain, Protein
DXZ73_RS29620	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DXZ73_RS29640	COG2018	Roadblock/LC7 domain
DXZ73_RS29660	COG2018	Roadblock/LC7 domain
DXZ73_RS29675	COG0179	Fumarylacetoacetate (FAA) hydrolase
DXZ73_RS29680	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DXZ73_RS29720	COG1414	Transcriptional regulator
DXZ73_RS29725	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DXZ73_RS29730	COG0066	3-isopropylmalate dehydratase activity
DXZ73_RS29740	COG0776	regulation of translation
DXZ73_RS29750	COG1920	GTP binding
DXZ73_RS29760	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DXZ73_RS29765	COG1181	Belongs to the D-alanine--D-alanine ligase family
DXZ73_RS29785	COG0351	phosphomethylpyrimidine kinase
DXZ73_RS29790	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DXZ73_RS29795	COG1461	Dihydroxyacetone kinase
DXZ73_RS29805	COG0742	ribosomal rna small subunit methyltransferase
DXZ73_RS29810	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DXZ73_RS29825	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DXZ73_RS29830	COG0571	ribonuclease III activity
DXZ73_RS29835	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DXZ73_RS29845	COG1254	Belongs to the acylphosphatase family
DXZ73_RS29865	COG0477	Major facilitator Superfamily
DXZ73_RS29870	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
DXZ73_RS29900	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
DXZ73_RS29915	COG0442	prolyl-tRNA aminoacylation
DXZ73_RS29925	COG0228	four-way junction DNA binding
DXZ73_RS29930	COG1837	Belongs to the UPF0109 family
DXZ73_RS29935	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DXZ73_RS29940	COG0336	Belongs to the RNA methyltransferase TrmD family
DXZ73_RS29945	COG0335	large ribosomal subunit rRNA binding
DXZ73_RS29955	COG0681	Belongs to the peptidase S26 family
DXZ73_RS29960	COG0681	Belongs to the peptidase S26 family
DXZ73_RS29965	COG0681	Belongs to the peptidase S26 family
DXZ73_RS29980	COG0792	nuclease activity
DXZ73_RS29995	COG1191	sigma factor activity
DXZ73_RS30010	COG0052	Belongs to the universal ribosomal protein uS2 family
DXZ73_RS30015	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DXZ73_RS30020	COG0528	UMP kinase activity
DXZ73_RS30025	COG0233	cytoplasmic translational termination
DXZ73_RS30035	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DXZ73_RS30050	COG3842	ATPase activity
DXZ73_RS30070	COG1136	(ABC) transporter
DXZ73_RS30075	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DXZ73_RS30085	COG1012	belongs to the aldehyde dehydrogenase family
DXZ73_RS30115	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DXZ73_RS30130	COG1012	belongs to the aldehyde dehydrogenase family
DXZ73_RS30135	COG3842	ATPase activity
DXZ73_RS30140	COG1176	ABC-type spermidine putrescine transport system, permease component I
DXZ73_RS30145	COG1177	transmembrane transport
DXZ73_RS30150	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DXZ73_RS30175	COG2508	Transcriptional regulator
DXZ73_RS30195	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DXZ73_RS30200	COG0750	zinc metalloprotease
DXZ73_RS30205	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DXZ73_RS30220	COG0442	prolyl-tRNA aminoacylation
DXZ73_RS30240	COG0779	Required for maturation of 30S ribosomal subunits
DXZ73_RS30255	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DXZ73_RS30265	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DXZ73_RS30270	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DXZ73_RS30310	COG3266	domain, Protein
DXZ73_RS30315	COG1404	Belongs to the peptidase S8 family
DXZ73_RS30395	COG1674	ftsk spoiiie
DXZ73_RS30405	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DXZ73_RS30410	COG1185	polyribonucleotide nucleotidyltransferase activity
DXZ73_RS30415	COG0612	Peptidase, M16
DXZ73_RS30420	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DXZ73_RS30440	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
DXZ73_RS30445	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DXZ73_RS30450	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DXZ73_RS30485	COG2770	Histidine kinase
DXZ73_RS30485	COG2208	phosphoserine phosphatase activity
DXZ73_RS30505	COG1674	ftsk spoiiie
DXZ73_RS30515	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DXZ73_RS30525	COG1546	Belongs to the CinA family
DXZ73_RS30525	COG1058	Belongs to the CinA family
DXZ73_RS30530	COG1396	sequence-specific DNA binding
DXZ73_RS30550	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DXZ73_RS30555	COG1201	RNA secondary structure unwinding
DXZ73_RS30575	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DXZ73_RS30585	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DXZ73_RS30600	COG0765	amino acid transport
DXZ73_RS30605	COG0765	amino acid transport
DXZ73_RS30610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DXZ73_RS30615	COG1126	abc transporter atp-binding protein
DXZ73_RS30620	COG0745	RESPONSE REGULATOR receiver
DXZ73_RS30625	COG2205	protein histidine kinase activity
DXZ73_RS30665	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DXZ73_RS30685	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DXZ73_RS30695	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DXZ73_RS30700	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DXZ73_RS30710	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DXZ73_RS30740	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DXZ73_RS30745	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DXZ73_RS30750	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DXZ73_RS30770	COG2162	N-hydroxyarylamine O-acetyltransferase activity
DXZ73_RS30785	COG0588	phosphoglycerate mutase activity
DXZ73_RS30795	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DXZ73_RS30810	COG0514	ATP-dependent DNA helicase (RecQ)
DXZ73_RS30825	COG1131	(ABC) transporter
DXZ73_RS30830	COG1802	Transcriptional regulator
DXZ73_RS30835	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DXZ73_RS30850	COG0187	DNA topoisomerase II activity
DXZ73_RS30860	COG4585	Histidine kinase
DXZ73_RS30865	COG2197	response regulator
DXZ73_RS30870	COG4565	transcriptional regulatory protein
DXZ73_RS30875	COG3290	protein histidine kinase activity
DXZ73_RS30885	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DXZ73_RS30905	COG0372	Belongs to the citrate synthase family
DXZ73_RS30915	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DXZ73_RS30920	COG0612	Peptidase, M16
DXZ73_RS30935	COG1802	Transcriptional regulator
DXZ73_RS30940	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DXZ73_RS30945	COG1042	CoA-binding domain protein
DXZ73_RS30945	COG0045	succinate-CoA ligase (ADP-forming) activity
DXZ73_RS30945	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DXZ73_RS30960	COG1435	thymidine kinase activity
DXZ73_RS30970	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
DXZ73_RS31025	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
DXZ73_RS31030	COG0483	inositol monophosphate 1-phosphatase activity
DXZ73_RS31035	COG0745	RESPONSE REGULATOR receiver
DXZ73_RS31040	COG2205	protein histidine kinase activity
DXZ73_RS31065	COG0756	dUTP diphosphatase activity
DXZ73_RS31080	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DXZ73_RS31085	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
DXZ73_RS31090	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
DXZ73_RS31130	COG0569	domain protein
DXZ73_RS31170	COG0531	amino acid
DXZ73_RS31175	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DXZ73_RS31240	COG2402	Toxic component of a toxin-antitoxin (TA) module. An RNase
DXZ73_RS31370	COG2197	response regulator
DXZ73_RS31375	COG4585	Histidine kinase
DXZ73_RS31385	COG3402	PFAM membrane-flanked domain
DXZ73_RS31400	COG3321	synthase
DXZ73_RS31400	COG0604	alcohol dehydrogenase
DXZ73_RS31415	COG3321	synthase
DXZ73_RS31415	COG0604	alcohol dehydrogenase
DXZ73_RS31430	COG3321	synthase
DXZ73_RS31430	COG0604	alcohol dehydrogenase
DXZ73_RS31435	COG3321	synthase
DXZ73_RS31435	COG0604	alcohol dehydrogenase
DXZ73_RS31460	COG2197	response regulator
DXZ73_RS31480	COG3844	kynureninase activity
DXZ73_RS31490	COG3483	tryptophan 2,3-dioxygenase activity
DXZ73_RS31505	COG2151	metal-sulfur cluster biosynthetic enzyme
DXZ73_RS31510	COG3396	Phenylacetate-CoA oxygenase
DXZ73_RS31520	COG3396	Phenylacetate-CoA oxygenase
DXZ73_RS31530	COG0318	PFAM AMP-dependent synthetase and ligase
DXZ73_RS31540	COG0604	alcohol dehydrogenase
DXZ73_RS31555	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DXZ73_RS31555	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DXZ73_RS31565	COG1595	DNA-templated transcription, initiation
DXZ73_RS31570	COG1799	cell septum assembly
DXZ73_RS31605	COG2040	homocysteine
DXZ73_RS31640	COG4977	sequence-specific DNA binding
DXZ73_RS31645	COG0477	Major facilitator Superfamily
DXZ73_RS31650	COG2235	arginine
DXZ73_RS31655	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DXZ73_RS31660	COG1024	Enoyl-CoA hydratase
DXZ73_RS31680	COG1960	acyl-CoA dehydrogenase activity
DXZ73_RS31705	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DXZ73_RS31710	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DXZ73_RS31740	COG1653	transport
DXZ73_RS31745	COG1175	transmembrane transport
DXZ73_RS31750	COG0395	ABC-type sugar transport system, permease component
DXZ73_RS31775	COG4213	ABC transporter substrate-binding protein
DXZ73_RS31785	COG4214	carbohydrate transport
DXZ73_RS31795	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DXZ73_RS31800	COG0531	amino acid
DXZ73_RS31845	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DXZ73_RS31855	COG4195	phage-related replication protein
DXZ73_RS31860	COG1250	3-hydroxyacyl-CoA dehydrogenase
DXZ73_RS31860	COG1024	Enoyl-CoA hydratase
DXZ73_RS31865	COG0183	Belongs to the thiolase family
DXZ73_RS31885	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
DXZ73_RS31890	COG0446	pyridine nucleotide-disulphide oxidoreductase
DXZ73_RS31895	COG3485	protocatechuate 3,4-dioxygenase
DXZ73_RS31900	COG3485	protocatechuate 3,4-dioxygenase
DXZ73_RS31910	COG1414	Transcriptional regulator
DXZ73_RS31915	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
DXZ73_RS31920	COG3253	May function as heme-dependent peroxidase
DXZ73_RS31925	COG0596	Alpha beta hydrolase
DXZ73_RS31950	COG2837	iron assimilation
DXZ73_RS31965	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DXZ73_RS32005	COG1136	(ABC) transporter
DXZ73_RS32010	COG0577	efflux transmembrane transporter activity
DXZ73_RS32015	COG4585	Histidine kinase
DXZ73_RS32020	COG2197	response regulator
DXZ73_RS32025	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DXZ73_RS32030	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DXZ73_RS32080	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DXZ73_RS32085	COG1116	anion transmembrane transporter activity
DXZ73_RS32105	COG0529	Catalyzes the synthesis of activated sulfate
DXZ73_RS32110	COG0175	sulfate reduction
DXZ73_RS32140	COG1162	GTPase activity
DXZ73_RS32185	COG1802	Transcriptional regulator
DXZ73_RS32220	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DXZ73_RS32225	COG2252	PERMEase
DXZ73_RS32270	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DXZ73_RS32310	COG0598	Magnesium transport protein CorA
DXZ73_RS32325	COG2197	response regulator
DXZ73_RS32330	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DXZ73_RS32335	COG0318	PFAM AMP-dependent synthetase and ligase
DXZ73_RS32345	COG3960	tartronate-semialdehyde synthase activity
DXZ73_RS32350	COG2084	Dehydrogenase
DXZ73_RS32355	COG3622	Belongs to the hyi family
DXZ73_RS32375	COG2351	hydroxyisourate hydrolase activity
DXZ73_RS32390	COG2233	PERMEase
DXZ73_RS32400	COG3547	Transposase (IS116 IS110 IS902 family)
DXZ73_RS32405	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DXZ73_RS32435	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DXZ73_RS32440	COG0746	molybdenum cofactor guanylyltransferase activity
DXZ73_RS32450	COG1414	Transcriptional regulator
DXZ73_RS32455	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DXZ73_RS32460	COG4266	Belongs to the allantoicase family
DXZ73_RS32555	COG2188	Transcriptional regulator
DXZ73_RS32560	COG1879	ABC-type sugar transport system periplasmic component
DXZ73_RS32565	COG1172	Belongs to the binding-protein-dependent transport system permease family
DXZ73_RS32575	COG1940	carbohydrate kinase activity
DXZ73_RS32585	COG3903	Transcriptional regulator
DXZ73_RS32585	COG3629	intracellular signal transduction
DXZ73_RS32590	COG3629	intracellular signal transduction
DXZ73_RS32590	COG3903	Transcriptional regulator
DXZ73_RS32635	COG3903	Transcriptional regulator
DXZ73_RS32635	COG3629	intracellular signal transduction
DXZ73_RS32650	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DXZ73_RS32655	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
DXZ73_RS32680	COG1126	abc transporter atp-binding protein
DXZ73_RS32685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DXZ73_RS32690	COG0765	amino acid transport
DXZ73_RS32695	COG0765	amino acid transport
DXZ73_RS32700	COG0667	Aldo Keto reductase
DXZ73_RS32715	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DXZ73_RS32730	COG1017	nitric oxide dioxygenase activity
DXZ73_RS32730	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DXZ73_RS32735	COG1959	2 iron, 2 sulfur cluster binding
DXZ73_RS32760	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DXZ73_RS32775	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DXZ73_RS32785	COG1940	carbohydrate kinase activity
DXZ73_RS32800	COG1082	Xylose isomerase domain protein TIM barrel
DXZ73_RS32805	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DXZ73_RS32810	COG2814	Major facilitator Superfamily
DXZ73_RS32820	COG2755	lipolytic protein G-D-S-L family
DXZ73_RS32825	COG0405	Gamma-glutamyltransferase
DXZ73_RS32835	COG0542	response to heat
DXZ73_RS32845	COG0483	inositol monophosphate 1-phosphatase activity
DXZ73_RS32870	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DXZ73_RS32875	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DXZ73_RS32890	COG0477	Major facilitator Superfamily
DXZ73_RS32895	COG1335	isochorismatase
DXZ73_RS32905	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DXZ73_RS32920	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DXZ73_RS32955	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DXZ73_RS32960	COG1929	Belongs to the glycerate kinase type-1 family
DXZ73_RS32970	COG0688	phosphatidylethanolamine metabolic process
DXZ73_RS32975	COG1960	acyl-CoA dehydrogenase activity
DXZ73_RS32990	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DXZ73_RS32990	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DXZ73_RS33005	COG1250	3-hydroxyacyl-CoA dehydrogenase
DXZ73_RS33025	COG2208	phosphoserine phosphatase activity
DXZ73_RS33025	COG2172	sigma factor antagonist activity
DXZ73_RS33025	COG1366	Belongs to the anti-sigma-factor antagonist family
DXZ73_RS33030	COG4106	trans-aconitate 2-methyltransferase activity
DXZ73_RS33040	COG2272	Belongs to the type-B carboxylesterase lipase family
DXZ73_RS33060	COG2362	D-Aminopeptidase
DXZ73_RS33065	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DXZ73_RS33075	COG1028	Short-chain dehydrogenase reductase Sdr
DXZ73_RS33080	COG1169	isochorismate synthase
DXZ73_RS33085	COG1021	2,3-dihydroxybenzoate-AMP ligase
DXZ73_RS33090	COG3433	isochorismatase activity
DXZ73_RS33090	COG1535	isochorismatase
DXZ73_RS33095	COG1535	isochorismatase
DXZ73_RS33095	COG3433	isochorismatase activity
DXZ73_RS33120	COG0346	lactoylglutathione lyase activity
DXZ73_RS33140	COG0667	Aldo Keto reductase
DXZ73_RS33150	COG0659	secondary active sulfate transmembrane transporter activity
DXZ73_RS33155	COG0477	Major facilitator Superfamily
DXZ73_RS33165	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DXZ73_RS33200	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
DXZ73_RS33210	COG0028	Belongs to the TPP enzyme family
DXZ73_RS33235	COG0531	amino acid
DXZ73_RS33240	COG1028	Short-chain dehydrogenase reductase Sdr
DXZ73_RS33245	COG1309	transcriptional regulator
DXZ73_RS33275	COG2154	pterin-4-alpha-carbinolamine dehydratase
DXZ73_RS33285	COG0656	L-ascorbic acid biosynthetic process
DXZ73_RS33320	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DXZ73_RS33340	COG0477	Major facilitator Superfamily
DXZ73_RS33355	COG1960	acyl-CoA dehydrogenase activity
DXZ73_RS33360	COG1960	acyl-CoA dehydrogenase activity
DXZ73_RS33370	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DXZ73_RS33395	COG1515	deoxyribonuclease V activity
DXZ73_RS33420	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DXZ73_RS33425	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DXZ73_RS33435	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DXZ73_RS33440	COG1960	acyl-CoA dehydrogenase activity
DXZ73_RS33445	COG0183	Belongs to the thiolase family
DXZ73_RS33450	COG1250	3-hydroxyacyl-CoA dehydrogenase
DXZ73_RS33450	COG1024	Enoyl-CoA hydratase
DXZ73_RS33460	COG0308	aminopeptidase N
DXZ73_RS33465	COG2936	dipeptidyl-peptidase activity
DXZ73_RS33470	COG0488	(ABC) transporter
DXZ73_RS33485	COG1357	PFAM Pentapeptide repeats (8 copies)
DXZ73_RS33490	COG2183	response to ionizing radiation
DXZ73_RS33500	COG4977	sequence-specific DNA binding
DXZ73_RS33510	COG1024	Enoyl-CoA hydratase
DXZ73_RS33525	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
DXZ73_RS33570	COG1388	LysM domain
DXZ73_RS33570	COG1134	teichoic acid transport
DXZ73_RS33575	COG1562	ergosterol biosynthetic process
DXZ73_RS33585	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
DXZ73_RS33595	COG1657	PFAM Prenyltransferase squalene oxidase
DXZ73_RS33610	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DXZ73_RS33615	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DXZ73_RS33630	COG3220	belongs to the UPF0276 family
DXZ73_RS33635	COG3220	belongs to the UPF0276 family
DXZ73_RS33660	COG2755	lipolytic protein G-D-S-L family
DXZ73_RS33680	COG1228	amidohydrolase
DXZ73_RS33685	COG3958	Transketolase
DXZ73_RS33690	COG3959	Transketolase, thiamine diphosphate binding domain
DXZ73_RS33700	COG0583	DNA-binding transcription factor activity
DXZ73_RS33710	COG1250	3-hydroxyacyl-CoA dehydrogenase
DXZ73_RS33730	COG0076	glutamate decarboxylase activity
DXZ73_RS33750	COG2267	carboxylic ester hydrolase activity
DXZ73_RS33755	COG0577	efflux transmembrane transporter activity
DXZ73_RS33755	COG1136	(ABC) transporter
DXZ73_RS33760	COG0577	efflux transmembrane transporter activity
DXZ73_RS33760	COG1136	(ABC) transporter
DXZ73_RS33765	COG2205	protein histidine kinase activity
DXZ73_RS33770	COG0745	RESPONSE REGULATOR receiver
DXZ73_RS33775	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
DXZ73_RS33800	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
DXZ73_RS33815	COG1902	pentaerythritol trinitrate reductase activity
DXZ73_RS33815	COG0446	pyridine nucleotide-disulphide oxidoreductase
DXZ73_RS33870	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
DXZ73_RS33875	COG0477	Major facilitator Superfamily
DXZ73_RS33880	COG0531	amino acid
DXZ73_RS33900	COG0640	Transcriptional regulator
DXZ73_RS33905	COG1116	anion transmembrane transporter activity
DXZ73_RS33915	COG0204	Acyl-transferase
DXZ73_RS33925	COG0640	Transcriptional regulator
DXZ73_RS33945	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DXZ73_RS33985	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DXZ73_RS34000	COG2264	protein methyltransferase activity
DXZ73_RS34020	COG1131	(ABC) transporter
DXZ73_RS34025	COG2259	Doxx family
DXZ73_RS34065	COG0318	PFAM AMP-dependent synthetase and ligase
DXZ73_RS34070	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DXZ73_RS34075	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DXZ73_RS34080	COG0667	Aldo Keto reductase
DXZ73_RS34095	COG3629	intracellular signal transduction
DXZ73_RS34095	COG3903	Transcriptional regulator
DXZ73_RS34140	COG0494	nUDIX hydrolase
DXZ73_RS34145	COG0590	tRNA wobble adenosine to inosine editing
DXZ73_RS34160	COG0583	DNA-binding transcription factor activity
DXZ73_RS34165	COG2124	cytochrome p450
DXZ73_RS34170	COG2011	ABC-type metal ion transport system permease component
DXZ73_RS34175	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DXZ73_RS34190	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DXZ73_RS34200	COG0318	PFAM AMP-dependent synthetase and ligase
DXZ73_RS34230	COG1773	rubredoxin
DXZ73_RS34235	COG2124	cytochrome p450
DXZ73_RS34275	COG1120	ATPase activity
DXZ73_RS34280	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DXZ73_RS34290	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DXZ73_RS34300	COG2814	Major facilitator Superfamily
DXZ73_RS34305	COG2382	esterase
DXZ73_RS34310	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DXZ73_RS34350	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DXZ73_RS34355	COG1879	ABC-type sugar transport system periplasmic component
DXZ73_RS34360	COG1172	Belongs to the binding-protein-dependent transport system permease family
DXZ73_RS34365	COG1129	ABC transporter
DXZ73_RS34370	COG1609	Transcriptional regulator
DXZ73_RS34375	COG0326	Molecular chaperone. Has ATPase activity
DXZ73_RS34390	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
DXZ73_RS34395	COG1191	sigma factor activity
DXZ73_RS34415	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DXZ73_RS34515	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DXZ73_RS34515	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DXZ73_RS34545	COG0270	DNA (cytosine-5-)-methyltransferase activity
DXZ73_RS34740	COG0531	amino acid
DXZ73_RS34745	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
DXZ73_RS34775	COG0745	RESPONSE REGULATOR receiver
DXZ73_RS34780	COG5002	protein histidine kinase activity
DXZ73_RS34805	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DXZ73_RS34810	COG0531	amino acid
DXZ73_RS34815	COG3537	Alpha-1,2-mannosidase
DXZ73_RS34835	COG3360	Dodecin
DXZ73_RS34845	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
DXZ73_RS34855	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DXZ73_RS34865	COG2124	cytochrome p450
DXZ73_RS34880	COG1024	Enoyl-CoA hydratase
DXZ73_RS34885	COG1960	acyl-CoA dehydrogenase activity
DXZ73_RS34895	COG3858	chitin binding
DXZ73_RS34900	COG0745	RESPONSE REGULATOR receiver
DXZ73_RS34905	COG2205	protein histidine kinase activity
DXZ73_RS34935	COG1960	acyl-CoA dehydrogenase activity
DXZ73_RS34940	COG1960	acyl-CoA dehydrogenase activity
DXZ73_RS34945	COG1024	Enoyl-CoA hydratase
DXZ73_RS34955	COG1309	transcriptional regulator
DXZ73_RS34960	COG0183	Belongs to the thiolase family
DXZ73_RS34965	COG1028	Short-chain dehydrogenase reductase Sdr
DXZ73_RS34990	COG1024	Enoyl-CoA hydratase
DXZ73_RS35000	COG1028	Short-chain dehydrogenase reductase Sdr
DXZ73_RS35055	COG0395	ABC-type sugar transport system, permease component
DXZ73_RS35060	COG1175	transmembrane transport
DXZ73_RS35070	COG1609	Transcriptional regulator
DXZ73_RS35080	COG1960	acyl-CoA dehydrogenase activity
DXZ73_RS35085	COG1960	acyl-CoA dehydrogenase activity
DXZ73_RS35105	COG2261	transglycosylase associated protein
DXZ73_RS35125	COG0456	acetyltransferase
DXZ73_RS35185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DXZ73_RS35190	COG0444	Belongs to the ABC transporter superfamily
DXZ73_RS35195	COG1124	(ABC) transporter
DXZ73_RS35200	COG0697	spore germination
DXZ73_RS35205	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DXZ73_RS35205	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DXZ73_RS35215	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DXZ73_RS35220	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DXZ73_RS35240	COG2353	YceI-like domain
DXZ73_RS35250	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DXZ73_RS35255	COG3239	Fatty acid desaturase
DXZ73_RS35275	COG3511	phospholipase C
DXZ73_RS35300	COG2018	Roadblock/LC7 domain
DXZ73_RS35310	COG1946	Acyl-CoA thioesterase
DXZ73_RS35325	COG1132	(ABC) transporter
DXZ73_RS35330	COG1132	(ABC) transporter
DXZ73_RS35340	COG1846	Transcriptional regulator
DXZ73_RS35345	COG1132	(ABC) transporter
DXZ73_RS35355	COG0477	Major facilitator Superfamily
DXZ73_RS35370	COG1556	Lactate utilization protein
DXZ73_RS35375	COG1139	Iron-sulfur cluster binding protein
DXZ73_RS35380	COG0247	lactate metabolic process
DXZ73_RS35395	COG1522	sequence-specific DNA binding
DXZ73_RS35405	COG2706	6-phosphogluconolactonase activity
DXZ73_RS35420	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DXZ73_RS35425	COG1902	pentaerythritol trinitrate reductase activity
DXZ73_RS35435	COG0640	Transcriptional regulator
DXZ73_RS35465	COG1278	Cold shock
DXZ73_RS35470	COG0513	Belongs to the DEAD box helicase family
DXZ73_RS35480	COG1012	belongs to the aldehyde dehydrogenase family
DXZ73_RS35500	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DXZ73_RS35515	COG0604	alcohol dehydrogenase
DXZ73_RS35515	COG3321	synthase
DXZ73_RS35525	COG0604	alcohol dehydrogenase
DXZ73_RS35525	COG3321	synthase
DXZ73_RS35525	COG3321	synthase
DXZ73_RS35525	COG0604	alcohol dehydrogenase
DXZ73_RS35540	COG0604	alcohol dehydrogenase
DXZ73_RS35570	COG0668	transmembrane transport
DXZ73_RS35650	COG0671	phosphoesterase, PA-phosphatase related
DXZ73_RS35675	COG3152	Membrane
DXZ73_RS35695	COG0765	amino acid transport
DXZ73_RS35700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DXZ73_RS35740	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DXZ73_RS35760	COG1660	Displays ATPase and GTPase activities
DXZ73_RS35770	COG0445	tRNA wobble uridine modification
DXZ73_RS35800	COG1940	carbohydrate kinase activity
DXZ73_RS35830	COG1349	DNA-binding transcription factor activity
DXZ73_RS35845	COG3217	Mosc domain protein beta barrel domain protein
DXZ73_RS35845	COG0633	Ferredoxin
DXZ73_RS35855	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DXZ73_RS35875	COG3629	intracellular signal transduction
DXZ73_RS35875	COG3903	Transcriptional regulator
DXZ73_RS35965	COG1397	ADP-ribosylglycohydrolase
DXZ73_RS35995	COG0604	alcohol dehydrogenase
DXZ73_RS35995	COG3321	synthase
DXZ73_RS36005	COG0604	alcohol dehydrogenase
DXZ73_RS36005	COG3321	synthase
DXZ73_RS36020	COG0604	alcohol dehydrogenase
DXZ73_RS36020	COG3321	synthase
DXZ73_RS36020	COG0604	alcohol dehydrogenase
DXZ73_RS36020	COG3321	synthase
DXZ73_RS36035	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DXZ73_RS36070	COG3408	Glycogen debranching enzyme
DXZ73_RS36070	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
DXZ73_RS36090	COG3903	Transcriptional regulator
DXZ73_RS36090	COG3629	intracellular signal transduction
DXZ73_RS36125	COG0488	(ABC) transporter
DXZ73_RS36145	COG1113	amino acid transport
DXZ73_RS36150	COG0477	Major facilitator Superfamily
DXZ73_RS36165	COG3486	L-lysine 6-monooxygenase (NADPH) activity
DXZ73_RS36170	COG0076	glutamate decarboxylase activity
DXZ73_RS36210	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
DXZ73_RS36215	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
DXZ73_RS36220	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DXZ73_RS36230	COG3547	Transposase (IS116 IS110 IS902 family)
DXZ73_RS36235	COG3387	PFAM Glycoside hydrolase 15-related
DXZ73_RS36240	COG0477	Major facilitator Superfamily
DXZ73_RS36260	COG4552	Acetyltransferase involved in intracellular survival and related
DXZ73_RS36350	COG1309	transcriptional regulator
DXZ73_RS36365	COG1132	(ABC) transporter
DXZ73_RS36385	COG3511	phospholipase C
DXZ73_RS36405	COG0531	amino acid
DXZ73_RS36410	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DXZ73_RS36420	COG0583	DNA-binding transcription factor activity
DXZ73_RS36430	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DXZ73_RS36455	COG0488	(ABC) transporter
DXZ73_RS36490	COG2319	Wd-40 repeat
DXZ73_RS36490	COG4249	Peptidase C14 caspase catalytic subunit p20
DXZ73_RS36510	COG0583	DNA-binding transcription factor activity
DXZ73_RS36525	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DXZ73_RS36535	COG0596	Alpha beta hydrolase
DXZ73_RS36555	COG0386	Belongs to the glutathione peroxidase family
DXZ73_RS36575	COG2124	cytochrome p450
DXZ73_RS36585	COG3152	Membrane
DXZ73_RS36590	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
DXZ73_RS36635	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DXZ73_RS36640	COG0477	Major facilitator Superfamily
DXZ73_RS36660	COG0156	8-amino-7-oxononanoate synthase activity
DXZ73_RS36670	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DXZ73_RS36680	COG2130	NADP-dependent
DXZ73_RS36690	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DXZ73_RS36730	COG3548	integral membrane protein
DXZ73_RS36755	COG0590	tRNA wobble adenosine to inosine editing
DXZ73_RS36880	COG2957	Belongs to the agmatine deiminase family
DXZ73_RS36985	COG3293	Transposase
DXZ73_RS36995	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DXZ73_RS37035	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DXZ73_RS37035	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DXZ73_RS37040	COG0785	Cytochrome C biogenesis protein
DXZ73_RS37070	COG1136	(ABC) transporter
DXZ73_RS37070	COG0577	efflux transmembrane transporter activity
DXZ73_RS37075	COG0577	efflux transmembrane transporter activity
DXZ73_RS37085	COG0745	RESPONSE REGULATOR receiver
DXZ73_RS37090	COG2205	protein histidine kinase activity
DXZ73_RS37125	COG1136	(ABC) transporter
DXZ73_RS37130	COG0577	efflux transmembrane transporter activity
DXZ73_RS37140	COG2197	response regulator
DXZ73_RS37145	COG4585	Histidine kinase
DXZ73_RS37160	COG3385	transposase activity
DXZ73_RS37255	COG3599	regulation of cell shape
DXZ73_RS37260	COG4585	Histidine kinase
DXZ73_RS37265	COG2197	response regulator
DXZ73_RS37405	COG0277	FAD linked oxidase domain protein
DXZ73_RS37470	COG1012	belongs to the aldehyde dehydrogenase family
DXZ73_RS37475	COG1086	Polysaccharide biosynthesis protein
DXZ73_RS37520	COG0477	Major facilitator Superfamily
DXZ73_RS37540	COG4585	Histidine kinase
DXZ73_RS37545	COG2197	response regulator