locus-tag	class	description
B1H29_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
B1H29_RS00030	COG0419	ATPase involved in DNA repair
B1H29_RS00035	COG0420	3'-5' exonuclease activity
B1H29_RS00255	COG1857	crispr-associated protein
B1H29_RS00255	COG1857	crispr-associated protein
B1H29_RS00395	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B1H29_RS00400	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
B1H29_RS00405	COG3629	intracellular signal transduction
B1H29_RS00415	COG0477	Major facilitator Superfamily
B1H29_RS00435	COG2814	Major facilitator Superfamily
B1H29_RS00440	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
B1H29_RS00450	COG2124	cytochrome p450
B1H29_RS00455	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B1H29_RS00460	COG0604	alcohol dehydrogenase
B1H29_RS00495	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B1H29_RS00505	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
B1H29_RS00520	COG0529	Catalyzes the synthesis of activated sulfate
B1H29_RS00540	COG1116	anion transmembrane transporter activity
B1H29_RS00555	COG1132	(ABC) transporter
B1H29_RS00570	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
B1H29_RS00580	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
B1H29_RS00600	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B1H29_RS00610	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
B1H29_RS00625	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B1H29_RS00635	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
B1H29_RS00655	COG1262	PFAM Formylglycine-generating sulfatase enzyme
B1H29_RS00665	COG1262	PFAM Formylglycine-generating sulfatase enzyme
B1H29_RS00700	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
B1H29_RS00705	COG1131	(ABC) transporter
B1H29_RS00720	COG4977	sequence-specific DNA binding
B1H29_RS00745	COG0745	RESPONSE REGULATOR receiver
B1H29_RS00755	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
B1H29_RS00765	COG0154	amidase activity
B1H29_RS00845	COG2867	negative regulation of translational initiation
B1H29_RS00885	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B1H29_RS00910	COG0702	epimerase
B1H29_RS00935	COG0667	Aldo Keto reductase
B1H29_RS00940	COG1309	transcriptional regulator
B1H29_RS00970	COG1131	(ABC) transporter
B1H29_RS00975	COG1725	Transcriptional regulator
B1H29_RS00990	COG1535	isochorismatase
B1H29_RS00990	COG3433	isochorismatase activity
B1H29_RS01020	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
B1H29_RS01035	COG1309	transcriptional regulator
B1H29_RS01045	COG1121	(ABC) transporter
B1H29_RS01090	COG2182	Extracellular solute-binding protein
B1H29_RS01095	COG1175	transmembrane transport
B1H29_RS01100	COG0395	ABC-type sugar transport system, permease component
B1H29_RS01105	COG2723	6-phospho-beta-galactosidase activity
B1H29_RS01160	COG2318	DinB family
B1H29_RS01260	COG2318	DinB family
B1H29_RS01265	COG2197	response regulator
B1H29_RS01270	COG4585	Histidine kinase
B1H29_RS01295	COG2814	Major facilitator Superfamily
B1H29_RS01305	COG1609	Transcriptional regulator
B1H29_RS01325	COG1136	(ABC) transporter
B1H29_RS01325	COG0577	efflux transmembrane transporter activity
B1H29_RS01330	COG2197	response regulator
B1H29_RS01335	COG4585	Histidine kinase
B1H29_RS01340	COG3239	Fatty acid desaturase
B1H29_RS01390	COG1595	DNA-templated transcription, initiation
B1H29_RS01405	COG5640	endopeptidase activity
B1H29_RS01425	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
B1H29_RS01430	COG1132	(ABC) transporter
B1H29_RS01435	COG1132	(ABC) transporter
B1H29_RS01460	COG1120	ATPase activity
B1H29_RS01470	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B1H29_RS01490	COG2353	YceI-like domain
B1H29_RS01495	COG2353	YceI-like domain
B1H29_RS01505	COG1278	Cold shock
B1H29_RS01510	COG0513	Belongs to the DEAD box helicase family
B1H29_RS01530	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B1H29_RS01535	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B1H29_RS01540	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B1H29_RS01545	COG0318	PFAM AMP-dependent synthetase and ligase
B1H29_RS01555	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B1H29_RS01560	COG3321	synthase
B1H29_RS01560	COG0604	alcohol dehydrogenase
B1H29_RS01560	COG1028	Short-chain dehydrogenase reductase Sdr
B1H29_RS01580	COG2226	methyltransferase
B1H29_RS01625	COG3903	Transcriptional regulator
B1H29_RS01625	COG2197	response regulator
B1H29_RS01660	COG1278	Cold shock
B1H29_RS01685	COG1309	transcriptional regulator
B1H29_RS01730	COG2382	esterase
B1H29_RS01735	COG1132	(ABC) transporter
B1H29_RS01745	COG1132	(ABC) transporter
B1H29_RS01750	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
B1H29_RS01755	COG1120	ATPase activity
B1H29_RS01760	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B1H29_RS01765	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B1H29_RS01770	COG3486	L-lysine 6-monooxygenase (NADPH) activity
B1H29_RS01805	COG0513	Belongs to the DEAD box helicase family
B1H29_RS01810	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
B1H29_RS01825	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
B1H29_RS01850	COG1476	TRANSCRIPTIONal
B1H29_RS01865	COG0612	Peptidase, M16
B1H29_RS01875	COG1668	transmembrane transport
B1H29_RS01880	COG4152	abc transporter atp-binding protein
B1H29_RS01890	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
B1H29_RS01895	COG1132	(ABC) transporter
B1H29_RS01920	COG1522	sequence-specific DNA binding
B1H29_RS01925	COG3386	PFAM SMP-30 Gluconolaconase
B1H29_RS01940	COG1278	Cold shock
B1H29_RS01960	COG0673	inositol 2-dehydrogenase activity
B1H29_RS01965	COG2188	Transcriptional regulator
B1H29_RS01970	COG2182	Extracellular solute-binding protein
B1H29_RS01975	COG1175	transmembrane transport
B1H29_RS01980	COG0395	ABC-type sugar transport system, permease component
B1H29_RS01985	COG3525	Glycosyl hydrolase, family 20, catalytic domain
B1H29_RS02010	COG1196	nuclear chromosome segregation
B1H29_RS02010	COG0741	lytic transglycosylase activity
B1H29_RS02010	COG0739	heme binding
B1H29_RS02025	COG2326	polyphosphate kinase activity
B1H29_RS02035	COG0667	Aldo Keto reductase
B1H29_RS02055	COG0438	transferase activity, transferring glycosyl groups
B1H29_RS02065	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B1H29_RS02070	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
B1H29_RS02100	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
B1H29_RS02115	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B1H29_RS02120	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B1H29_RS02125	COG2340	Cysteine-rich secretory protein family
B1H29_RS02130	COG2205	protein histidine kinase activity
B1H29_RS02135	COG0745	RESPONSE REGULATOR receiver
B1H29_RS02175	COG2271	Major facilitator Superfamily
B1H29_RS02185	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
B1H29_RS02210	COG0142	geranyltranstransferase activity
B1H29_RS02225	COG0142	geranyltranstransferase activity
B1H29_RS02230	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B1H29_RS02245	COG0384	phenazine biosynthesis protein PhzF
B1H29_RS02265	COG2267	carboxylic ester hydrolase activity
B1H29_RS02290	COG0655	NAD(P)H dehydrogenase (quinone) activity
B1H29_RS02300	COG0783	Belongs to the Dps family
B1H29_RS02320	COG1191	sigma factor activity
B1H29_RS02325	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
B1H29_RS02345	COG0505	Belongs to the CarA family
B1H29_RS02400	COG2235	arginine
B1H29_RS02425	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
B1H29_RS02430	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
B1H29_RS02435	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B1H29_RS02445	COG1937	Protein conserved in bacteria
B1H29_RS02450	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B1H29_RS02475	COG0477	Major facilitator Superfamily
B1H29_RS02495	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B1H29_RS02500	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
B1H29_RS02505	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
B1H29_RS02510	COG3639	organic phosphonate transmembrane transporter activity
B1H29_RS02540	COG0243	molybdopterin cofactor binding
B1H29_RS02585	COG1120	ATPase activity
B1H29_RS02590	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B1H29_RS02615	COG3397	chitin binding
B1H29_RS02630	COG1028	Short-chain dehydrogenase reductase Sdr
B1H29_RS02700	COG1175	transmembrane transport
B1H29_RS02705	COG0395	ABC-type sugar transport system, permease component
B1H29_RS02710	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B1H29_RS02730	COG1597	lipid kinase activity
B1H29_RS02735	COG0277	FAD linked oxidase domain protein
B1H29_RS02755	COG1366	Belongs to the anti-sigma-factor antagonist family
B1H29_RS02775	COG3290	protein histidine kinase activity
B1H29_RS02790	COG0477	Major facilitator Superfamily
B1H29_RS02820	COG1295	ribonuclease BN
B1H29_RS02825	COG1028	Short-chain dehydrogenase reductase Sdr
B1H29_RS02835	COG2080	2 iron, 2 sulfur cluster binding
B1H29_RS02840	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
B1H29_RS02845	COG1529	Aldehyde oxidase and xanthine dehydrogenase
B1H29_RS02890	COG0702	epimerase
B1H29_RS02895	COG3631	Ketosteroid isomerase-related protein
B1H29_RS02905	COG1132	(ABC) transporter
B1H29_RS02945	COG0559	Belongs to the binding-protein-dependent transport system permease family
B1H29_RS02950	COG0411	ABC transporter
B1H29_RS02955	COG0410	ABC transporter
B1H29_RS02960	COG0277	FAD linked oxidase domain protein
B1H29_RS02965	COG1231	oxidoreductase activity
B1H29_RS02970	COG2770	Histidine kinase
B1H29_RS02970	COG2208	phosphoserine phosphatase activity
B1H29_RS02975	COG0596	Alpha beta hydrolase
B1H29_RS02980	COG2508	Transcriptional regulator
B1H29_RS03090	COG1940	carbohydrate kinase activity
B1H29_RS03090	COG1846	Transcriptional regulator
B1H29_RS03100	COG0673	inositol 2-dehydrogenase activity
B1H29_RS03110	COG1028	Short-chain dehydrogenase reductase Sdr
B1H29_RS03120	COG1028	Short-chain dehydrogenase reductase Sdr
B1H29_RS03135	COG1132	(ABC) transporter
B1H29_RS03180	COG0517	IMP dehydrogenase activity
B1H29_RS03220	COG0248	Ppx GppA phosphatase
B1H29_RS03235	COG2890	protein-(glutamine-N5) methyltransferase activity
B1H29_RS03250	COG1304	FMN binding
B1H29_RS03275	COG3250	beta-galactosidase activity
B1H29_RS03290	COG0667	Aldo Keto reductase
B1H29_RS03315	COG2124	cytochrome p450
B1H29_RS03330	COG0435	Glutathione S-transferase
B1H29_RS03345	COG2124	cytochrome p450
B1H29_RS03385	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
B1H29_RS03415	COG1028	Short-chain dehydrogenase reductase Sdr
B1H29_RS03420	COG1796	DNA polymerase
B1H29_RS03420	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
B1H29_RS03425	COG0546	phosphoglycolate phosphatase activity
B1H29_RS03445	COG1940	carbohydrate kinase activity
B1H29_RS03470	COG1309	transcriptional regulator
B1H29_RS03475	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
B1H29_RS03475	COG2124	cytochrome p450
B1H29_RS03485	COG1595	DNA-templated transcription, initiation
B1H29_RS03500	COG1609	Transcriptional regulator
B1H29_RS03505	COG0247	lactate metabolic process
B1H29_RS03510	COG1139	Iron-sulfur cluster binding protein
B1H29_RS03515	COG1556	Lactate utilization protein
B1H29_RS03525	COG1136	(ABC) transporter
B1H29_RS03550	COG1725	Transcriptional regulator
B1H29_RS03555	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
B1H29_RS03575	COG3540	Alkaline phosphatase
B1H29_RS03615	COG0668	transmembrane transport
B1H29_RS03650	COG2409	Drug exporters of the RND superfamily
B1H29_RS03655	COG1846	Transcriptional regulator
B1H29_RS03660	COG0702	epimerase
B1H29_RS03730	COG1357	PFAM Pentapeptide repeats (8 copies)
B1H29_RS03740	COG3693	PFAM glycoside hydrolase, family 10
B1H29_RS03775	COG4124	Belongs to the glycosyl hydrolase 26 family
B1H29_RS03800	COG3833	ABC-type maltose transport systems, permease component
B1H29_RS03805	COG1175	transmembrane transport
B1H29_RS03815	COG1940	carbohydrate kinase activity
B1H29_RS03820	COG1115	amino acid carrier protein
B1H29_RS03845	COG0242	peptide deformylase activity
B1H29_RS03855	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B1H29_RS03860	COG1609	Transcriptional regulator
B1H29_RS03890	COG3976	FMN-binding domain protein
B1H29_RS03890	COG1053	succinate dehydrogenase
B1H29_RS03895	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
B1H29_RS03905	COG0517	IMP dehydrogenase activity
B1H29_RS03915	COG3903	Transcriptional regulator
B1H29_RS03915	COG3629	intracellular signal transduction
B1H29_RS03920	COG0596	Alpha beta hydrolase
B1H29_RS03945	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
B1H29_RS03960	COG3572	ergothioneine biosynthetic process
B1H29_RS03965	COG1262	PFAM Formylglycine-generating sulfatase enzyme
B1H29_RS03970	COG0121	glutamine amidotransferase
B1H29_RS03975	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
B1H29_RS03980	COG2182	Extracellular solute-binding protein
B1H29_RS03985	COG3360	Dodecin
B1H29_RS03995	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B1H29_RS04020	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
B1H29_RS04025	COG1053	succinate dehydrogenase
B1H29_RS04035	COG0583	DNA-binding transcription factor activity
B1H29_RS04040	COG5001	Diguanylate cyclase
B1H29_RS04080	COG0726	polysaccharide deacetylase
B1H29_RS04090	COG0531	amino acid
B1H29_RS04115	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
B1H29_RS04150	COG0395	ABC-type sugar transport system, permease component
B1H29_RS04155	COG1175	transmembrane transport
B1H29_RS04165	COG1609	Transcriptional regulator
B1H29_RS04205	COG3250	beta-galactosidase activity
B1H29_RS04210	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
B1H29_RS04215	COG0297	glycogen (starch) synthase activity
B1H29_RS04235	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
B1H29_RS04250	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
B1H29_RS04280	COG0745	RESPONSE REGULATOR receiver
B1H29_RS04285	COG2205	protein histidine kinase activity
B1H29_RS04290	COG2409	Drug exporters of the RND superfamily
B1H29_RS04330	COG0366	Alpha amylase catalytic
B1H29_RS04335	COG3833	ABC-type maltose transport systems, permease component
B1H29_RS04340	COG1175	transmembrane transport
B1H29_RS04345	COG2182	Extracellular solute-binding protein
B1H29_RS04350	COG1609	Transcriptional regulator
B1H29_RS04365	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
B1H29_RS04370	COG1131	(ABC) transporter
B1H29_RS04395	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
B1H29_RS04400	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B1H29_RS04405	COG0561	phosphatase activity
B1H29_RS04415	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
B1H29_RS04420	COG0662	Cupin 2, conserved barrel domain protein
B1H29_RS04440	COG4989	oxidoreductase activity
B1H29_RS04445	COG1874	Beta-galactosidase
B1H29_RS04445	COG0366	Alpha amylase catalytic
B1H29_RS04495	COG1401	restriction endodeoxyribonuclease activity
B1H29_RS04505	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
B1H29_RS04530	COG1401	restriction endodeoxyribonuclease activity
B1H29_RS04540	COG0210	DNA helicase
B1H29_RS04670	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B1H29_RS04685	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
B1H29_RS04700	COG3321	synthase
B1H29_RS04700	COG1028	Short-chain dehydrogenase reductase Sdr
B1H29_RS04700	COG0604	alcohol dehydrogenase
B1H29_RS04715	COG0475	glutathione-regulated potassium exporter activity
B1H29_RS04725	COG3903	Transcriptional regulator
B1H29_RS04725	COG3629	intracellular signal transduction
B1H29_RS04735	COG2169	Transcriptional regulator
B1H29_RS04740	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B1H29_RS04745	COG1028	Short-chain dehydrogenase reductase Sdr
B1H29_RS04765	COG3629	intracellular signal transduction
B1H29_RS04765	COG3903	Transcriptional regulator
B1H29_RS04800	COG3321	synthase
B1H29_RS04800	COG0604	alcohol dehydrogenase
B1H29_RS04825	COG3321	synthase
B1H29_RS04825	COG0604	alcohol dehydrogenase
B1H29_RS04830	COG3321	synthase
B1H29_RS04830	COG0604	alcohol dehydrogenase
B1H29_RS04840	COG0604	alcohol dehydrogenase
B1H29_RS04840	COG3321	synthase
B1H29_RS04850	COG3433	isochorismatase activity
B1H29_RS04850	COG2226	methyltransferase
B1H29_RS04850	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B1H29_RS04880	COG1063	alcohol dehydrogenase
B1H29_RS04915	COG2124	cytochrome p450
B1H29_RS04940	COG2409	Drug exporters of the RND superfamily
B1H29_RS04950	COG2124	cytochrome p450
B1H29_RS04980	COG1175	transmembrane transport
B1H29_RS04990	COG0366	Alpha amylase catalytic
B1H29_RS05000	COG1132	(ABC) transporter
B1H29_RS05010	COG0492	ferredoxin-NADP+ reductase activity
B1H29_RS05025	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
B1H29_RS05035	COG0531	amino acid
B1H29_RS05040	COG0668	transmembrane transport
B1H29_RS05045	COG2838	Isocitrate dehydrogenase
B1H29_RS05080	COG2197	response regulator
B1H29_RS05095	COG0385	Bile acid
B1H29_RS05105	COG2197	response regulator
B1H29_RS05110	COG4585	Histidine kinase
B1H29_RS05115	COG1131	(ABC) transporter
B1H29_RS05130	COG0673	inositol 2-dehydrogenase activity
B1H29_RS05135	COG2764	glyoxalase bleomycin resistance protein dioxygenase
B1H29_RS05160	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B1H29_RS05170	COG3718	enzyme involved in inositol metabolism
B1H29_RS05175	COG3962	Belongs to the TPP enzyme family
B1H29_RS05180	COG2188	Transcriptional regulator
B1H29_RS05220	COG0318	PFAM AMP-dependent synthetase and ligase
B1H29_RS05225	COG0183	Belongs to the thiolase family
B1H29_RS05230	COG2267	carboxylic ester hydrolase activity
B1H29_RS05255	COG0174	glutamine synthetase
B1H29_RS05300	COG0583	DNA-binding transcription factor activity
B1H29_RS05305	COG0156	8-amino-7-oxononanoate synthase activity
B1H29_RS05310	COG1063	alcohol dehydrogenase
B1H29_RS05365	COG0297	glycogen (starch) synthase activity
B1H29_RS05370	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
B1H29_RS05395	COG2755	lipolytic protein G-D-S-L family
B1H29_RS05405	COG2365	Tyrosine phosphatase family
B1H29_RS05425	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
B1H29_RS05430	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
B1H29_RS05445	COG1657	PFAM Prenyltransferase squalene oxidase
B1H29_RS05455	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
B1H29_RS05470	COG1562	ergosterol biosynthetic process
B1H29_RS05475	COG1134	teichoic acid transport
B1H29_RS05520	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
B1H29_RS05530	COG1024	Enoyl-CoA hydratase
B1H29_RS05540	COG4977	sequence-specific DNA binding
B1H29_RS05550	COG2183	response to ionizing radiation
B1H29_RS05555	COG0488	(ABC) transporter
B1H29_RS05570	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
B1H29_RS05580	COG2936	dipeptidyl-peptidase activity
B1H29_RS05595	COG1113	amino acid transport
B1H29_RS05605	COG1024	Enoyl-CoA hydratase
B1H29_RS05605	COG1250	3-hydroxyacyl-CoA dehydrogenase
B1H29_RS05610	COG0183	Belongs to the thiolase family
B1H29_RS05615	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B1H29_RS05620	COG3268	Saccharopine dehydrogenase
B1H29_RS05635	COG1515	deoxyribonuclease V activity
B1H29_RS05650	COG4447	cellulose binding
B1H29_RS05665	COG0488	(ABC) transporter
B1H29_RS05670	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
B1H29_RS05675	COG1834	amidinotransferase
B1H29_RS05730	COG1793	dna ligase
B1H29_RS05740	COG1470	cell adhesion involved in biofilm formation
B1H29_RS05760	COG0183	Belongs to the thiolase family
B1H29_RS05765	COG3485	protocatechuate 3,4-dioxygenase
B1H29_RS05770	COG3485	protocatechuate 3,4-dioxygenase
B1H29_RS05775	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
B1H29_RS05780	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B1H29_RS05810	COG3511	phospholipase C
B1H29_RS05835	COG1414	Transcriptional regulator
B1H29_RS05845	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B1H29_RS05850	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B1H29_RS05865	COG3938	Belongs to the proline racemase family
B1H29_RS05895	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B1H29_RS05925	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
B1H29_RS05935	COG1486	melibiose metabolic process
B1H29_RS05950	COG2197	response regulator
B1H29_RS05955	COG2409	Drug exporters of the RND superfamily
B1H29_RS05970	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
B1H29_RS05985	COG0166	Belongs to the GPI family
B1H29_RS05990	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
B1H29_RS06000	COG1082	Xylose isomerase domain protein TIM barrel
B1H29_RS06000	COG3185	4-Hydroxyphenylpyruvate dioxygenase
B1H29_RS06005	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
B1H29_RS06015	COG0477	Major facilitator Superfamily
B1H29_RS06025	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
B1H29_RS06040	COG0297	glycogen (starch) synthase activity
B1H29_RS06055	COG1183	phosphatidylcholine synthase activity
B1H29_RS06070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B1H29_RS06075	COG0747	negative chemotaxis
B1H29_RS06110	COG3552	Protein containing von Willebrand factor type A (VWA) domain
B1H29_RS06115	COG0714	Associated with various cellular activities
B1H29_RS06140	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
B1H29_RS06155	COG1012	belongs to the aldehyde dehydrogenase family
B1H29_RS06165	COG0045	succinate-CoA ligase (ADP-forming) activity
B1H29_RS06175	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B1H29_RS06185	COG2223	nitrite transmembrane transporter activity
B1H29_RS06225	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
B1H29_RS06245	COG0673	inositol 2-dehydrogenase activity
B1H29_RS06255	COG1172	Belongs to the binding-protein-dependent transport system permease family
B1H29_RS06260	COG1129	ABC transporter
B1H29_RS06275	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B1H29_RS06285	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
B1H29_RS06290	COG3383	formate dehydrogenase (NAD+) activity
B1H29_RS06305	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
B1H29_RS06325	COG0656	L-ascorbic acid biosynthetic process
B1H29_RS06330	COG2226	methyltransferase
B1H29_RS06335	COG5297	Belongs to the glycosyl hydrolase family 6
B1H29_RS06340	COG4733	cellulase activity
B1H29_RS06340	COG5297	Belongs to the glycosyl hydrolase family 6
B1H29_RS06355	COG3401	FG-GAP repeat protein
B1H29_RS06365	COG2154	pterin-4-alpha-carbinolamine dehydratase
B1H29_RS06380	COG0318	PFAM AMP-dependent synthetase and ligase
B1H29_RS06380	COG0300	oxidoreductase activity
B1H29_RS06380	COG1028	Short-chain dehydrogenase reductase Sdr
B1H29_RS06380	COG3321	synthase
B1H29_RS06380	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B1H29_RS06395	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B1H29_RS06400	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B1H29_RS06400	COG1028	Short-chain dehydrogenase reductase Sdr
B1H29_RS06400	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B1H29_RS06400	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B1H29_RS06400	COG3321	synthase
B1H29_RS06405	COG0300	oxidoreductase activity
B1H29_RS06405	COG3321	synthase
B1H29_RS06405	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B1H29_RS06405	COG4221	oxidoreductase activity
B1H29_RS06425	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B1H29_RS06425	COG0300	oxidoreductase activity
B1H29_RS06425	COG3321	synthase
B1H29_RS06425	COG4221	oxidoreductase activity
B1H29_RS06425	COG4221	oxidoreductase activity
B1H29_RS06425	COG3321	synthase
B1H29_RS06425	COG0300	oxidoreductase activity
B1H29_RS06425	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B1H29_RS06455	COG1140	nitrate reductase beta subunit
B1H29_RS06480	COG0531	amino acid
B1H29_RS06530	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
B1H29_RS06545	COG0693	protein deglycase activity
B1H29_RS06560	COG0488	(ABC) transporter
B1H29_RS06565	COG1597	lipid kinase activity
B1H29_RS06630	COG1793	dna ligase
B1H29_RS06630	COG3285	dna ligase
B1H29_RS06645	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B1H29_RS06675	COG1619	proteins homologs of microcin C7 resistance protein MccF
B1H29_RS06685	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B1H29_RS06690	COG2362	D-Aminopeptidase
B1H29_RS06695	COG2226	methyltransferase
B1H29_RS06700	COG2208	phosphoserine phosphatase activity
B1H29_RS06700	COG2172	sigma factor antagonist activity
B1H29_RS06700	COG1366	Belongs to the anti-sigma-factor antagonist family
B1H29_RS06725	COG0596	Alpha beta hydrolase
B1H29_RS06745	COG1250	3-hydroxyacyl-CoA dehydrogenase
B1H29_RS06760	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
B1H29_RS06760	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
B1H29_RS06765	COG2301	Belongs to the HpcH HpaI aldolase family
B1H29_RS06775	COG1960	acyl-CoA dehydrogenase activity
B1H29_RS06780	COG0688	phosphatidylethanolamine metabolic process
B1H29_RS06790	COG1929	Belongs to the glycerate kinase type-1 family
B1H29_RS06800	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
B1H29_RS06810	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
B1H29_RS06820	COG0640	Transcriptional regulator
B1H29_RS06835	COG3540	Alkaline phosphatase
B1H29_RS06845	COG0444	Belongs to the ABC transporter superfamily
B1H29_RS06850	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B1H29_RS06855	COG0601	transmembrane transport
B1H29_RS06865	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
B1H29_RS06870	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
B1H29_RS06885	COG0483	inositol monophosphate 1-phosphatase activity
B1H29_RS06910	COG1007	ATP synthesis coupled electron transport
B1H29_RS06920	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
B1H29_RS06925	COG0713	ATP synthesis coupled electron transport
B1H29_RS06935	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
B1H29_RS06945	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B1H29_RS06955	COG2197	response regulator
B1H29_RS06975	COG1953	Uracil, thiamine, allantoin
B1H29_RS06985	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
B1H29_RS07025	COG0542	response to heat
B1H29_RS07030	COG0405	Gamma-glutamyltransferase
B1H29_RS07060	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
B1H29_RS07065	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B1H29_RS07075	COG0640	Transcriptional regulator
B1H29_RS07090	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
B1H29_RS07100	COG1940	carbohydrate kinase activity
B1H29_RS07120	COG2188	Transcriptional regulator
B1H29_RS07125	COG0673	inositol 2-dehydrogenase activity
B1H29_RS07135	COG1028	Short-chain dehydrogenase reductase Sdr
B1H29_RS07140	COG4266	Belongs to the allantoicase family
B1H29_RS07145	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
B1H29_RS07150	COG1414	Transcriptional regulator
B1H29_RS07165	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
B1H29_RS07185	COG0747	negative chemotaxis
B1H29_RS07190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B1H29_RS07200	COG4608	Belongs to the ABC transporter superfamily
B1H29_RS07215	COG0492	ferredoxin-NADP+ reductase activity
B1H29_RS07225	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B1H29_RS07225	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
B1H29_RS07225	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
B1H29_RS07225	COG3321	synthase
B1H29_RS07235	COG1124	(ABC) transporter
B1H29_RS07240	COG3842	ATPase activity
B1H29_RS07265	COG3433	isochorismatase activity
B1H29_RS07265	COG2226	methyltransferase
B1H29_RS07265	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B1H29_RS07300	COG0436	Aminotransferase
B1H29_RS07305	COG0406	alpha-ribazole phosphatase activity
B1H29_RS07320	COG2233	PERMEase
B1H29_RS07330	COG2233	PERMEase
B1H29_RS07340	COG2351	hydroxyisourate hydrolase activity
B1H29_RS07360	COG3622	Belongs to the hyi family
B1H29_RS07365	COG2084	Dehydrogenase
B1H29_RS07370	COG0753	catalase activity
B1H29_RS07385	COG3960	tartronate-semialdehyde synthase activity
B1H29_RS07395	COG0318	PFAM AMP-dependent synthetase and ligase
B1H29_RS07400	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B1H29_RS07405	COG2197	response regulator
B1H29_RS07420	COG4249	Peptidase C14 caspase catalytic subunit p20
B1H29_RS07420	COG2319	Wd-40 repeat
B1H29_RS07460	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
B1H29_RS07460	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
B1H29_RS07465	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
B1H29_RS07470	COG0438	transferase activity, transferring glycosyl groups
B1H29_RS07475	COG0438	transferase activity, transferring glycosyl groups
B1H29_RS07480	COG0859	PFAM glycosyl transferase family 9
B1H29_RS07485	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
B1H29_RS07495	COG2192	nodulation
B1H29_RS07520	COG2252	PERMEase
B1H29_RS07525	COG1529	Aldehyde oxidase and xanthine dehydrogenase
B1H29_RS07575	COG3851	Histidine kinase
B1H29_RS07580	COG2197	response regulator
B1H29_RS07590	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B1H29_RS07595	COG1802	Transcriptional regulator
B1H29_RS07615	COG0028	Belongs to the TPP enzyme family
B1H29_RS07640	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
B1H29_RS07650	COG1162	GTPase activity
B1H29_RS07665	COG0277	FAD linked oxidase domain protein
B1H29_RS07725	COG2755	lipolytic protein G-D-S-L family
B1H29_RS07735	COG2197	response regulator
B1H29_RS07740	COG4585	Histidine kinase
B1H29_RS07750	COG2040	homocysteine
B1H29_RS07765	COG0714	Associated with various cellular activities
B1H29_RS07805	COG1609	Transcriptional regulator
B1H29_RS07820	COG1131	(ABC) transporter
B1H29_RS07915	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
B1H29_RS07935	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
B1H29_RS07945	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
B1H29_RS07985	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
B1H29_RS08075	COG1518	maintenance of DNA repeat elements
B1H29_RS08080	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B1H29_RS08105	COG3409	Peptidoglycan-binding domain 1 protein
B1H29_RS08130	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
B1H29_RS08160	COG1917	Cupin 2, conserved barrel domain protein
B1H29_RS08160	COG4977	sequence-specific DNA binding
B1H29_RS08175	COG1960	acyl-CoA dehydrogenase activity
B1H29_RS08205	COG0175	sulfate reduction
B1H29_RS08210	COG0529	Catalyzes the synthesis of activated sulfate
B1H29_RS08230	COG1116	anion transmembrane transporter activity
B1H29_RS08255	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
B1H29_RS08320	COG3173	Aminoglycoside phosphotransferase
B1H29_RS08330	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
B1H29_RS08350	COG1309	transcriptional regulator
B1H29_RS08395	COG1732	Glycine betaine
B1H29_RS08400	COG1174	glycine betaine transport
B1H29_RS08405	COG1174	glycine betaine transport
B1H29_RS08420	COG0745	RESPONSE REGULATOR receiver
B1H29_RS08425	COG2205	protein histidine kinase activity
B1H29_RS08430	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B1H29_RS08435	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
B1H29_RS08470	COG0330	HflC and HflK could
B1H29_RS08480	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B1H29_RS08480	COG0723	plastoquinol--plastocyanin reductase activity
B1H29_RS08500	COG1116	anion transmembrane transporter activity
B1H29_RS08515	COG3220	belongs to the UPF0276 family
B1H29_RS08530	COG3253	May function as heme-dependent peroxidase
B1H29_RS08535	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
B1H29_RS08545	COG0446	pyridine nucleotide-disulphide oxidoreductase
B1H29_RS08585	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
B1H29_RS08600	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
B1H29_RS08605	COG0183	Belongs to the thiolase family
B1H29_RS08610	COG1024	Enoyl-CoA hydratase
B1H29_RS08610	COG1250	3-hydroxyacyl-CoA dehydrogenase
B1H29_RS08630	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
B1H29_RS08650	COG0531	amino acid
B1H29_RS08655	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
B1H29_RS08665	COG4214	carbohydrate transport
B1H29_RS08675	COG4213	ABC transporter substrate-binding protein
B1H29_RS08680	COG1940	carbohydrate kinase activity
B1H29_RS08685	COG0395	ABC-type sugar transport system, permease component
B1H29_RS08690	COG1175	transmembrane transport
B1H29_RS08695	COG1653	transport
B1H29_RS08735	COG0395	ABC-type sugar transport system, permease component
B1H29_RS08740	COG4209	transmembrane transport
B1H29_RS08745	COG3458	cephalosporin-C deacetylase activity
B1H29_RS08755	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
B1H29_RS08765	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
B1H29_RS08775	COG0210	DNA helicase
B1H29_RS08825	COG0515	serine threonine protein kinase
B1H29_RS08825	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B1H29_RS08855	COG2205	protein histidine kinase activity
B1H29_RS08860	COG0745	RESPONSE REGULATOR receiver
B1H29_RS08870	COG2409	Drug exporters of the RND superfamily
B1H29_RS08895	COG1132	(ABC) transporter
B1H29_RS08900	COG0515	serine threonine protein kinase
B1H29_RS08980	COG1024	Enoyl-CoA hydratase
B1H29_RS08990	COG0531	amino acid
B1H29_RS08995	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
B1H29_RS09000	COG2235	arginine
B1H29_RS09025	COG0475	glutathione-regulated potassium exporter activity
B1H29_RS09035	COG2255	four-way junction helicase activity
B1H29_RS09085	COG1799	cell septum assembly
B1H29_RS09090	COG0277	FAD linked oxidase domain protein
B1H29_RS09090	COG0247	lactate metabolic process
B1H29_RS09105	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B1H29_RS09110	COG0310	cobalt ion transport
B1H29_RS09115	COG1930	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
B1H29_RS09125	COG1122	ATPase activity
B1H29_RS09130	COG0477	Major facilitator Superfamily
B1H29_RS09145	COG0531	amino acid
B1H29_RS09160	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B1H29_RS09160	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
B1H29_RS09160	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
B1H29_RS09160	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B1H29_RS09185	COG1132	(ABC) transporter
B1H29_RS09275	COG1250	3-hydroxyacyl-CoA dehydrogenase
B1H29_RS09300	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B1H29_RS09305	COG2124	cytochrome p450
B1H29_RS09310	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B1H29_RS09315	COG0300	oxidoreductase activity
B1H29_RS09315	COG0318	PFAM AMP-dependent synthetase and ligase
B1H29_RS09315	COG1028	Short-chain dehydrogenase reductase Sdr
B1H29_RS09315	COG3321	synthase
B1H29_RS09315	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B1H29_RS09325	COG3977	Valine--pyruvate aminotransferase
B1H29_RS09385	COG0596	Alpha beta hydrolase
B1H29_RS09395	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
B1H29_RS09400	COG0531	amino acid
B1H29_RS09405	COG0569	domain protein
B1H29_RS09440	COG0756	dUTP diphosphatase activity
B1H29_RS09465	COG2205	protein histidine kinase activity
B1H29_RS09470	COG0745	RESPONSE REGULATOR receiver
B1H29_RS09480	COG2826	transposase and inactivated derivatives, IS30 family
B1H29_RS09490	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
B1H29_RS09525	COG1435	thymidine kinase activity
B1H29_RS09550	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
B1H29_RS09555	COG1802	Transcriptional regulator
B1H29_RS09570	COG0612	Peptidase, M16
B1H29_RS09575	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
B1H29_RS09580	COG0523	cobalamin synthesis protein
B1H29_RS09595	COG0372	Belongs to the citrate synthase family
B1H29_RS09610	COG3290	protein histidine kinase activity
B1H29_RS09615	COG4565	transcriptional regulatory protein
B1H29_RS09620	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B1H29_RS09630	COG0187	DNA topoisomerase II activity
B1H29_RS09645	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
B1H29_RS09650	COG2186	Transcriptional regulator
B1H29_RS09675	COG0514	ATP-dependent DNA helicase (RecQ)
B1H29_RS09690	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
B1H29_RS09715	COG0588	phosphoglycerate mutase activity
B1H29_RS09730	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B1H29_RS09735	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
B1H29_RS09740	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
B1H29_RS09775	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
B1H29_RS09785	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
B1H29_RS09790	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
B1H29_RS09800	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
B1H29_RS09820	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
B1H29_RS09825	COG2197	response regulator
B1H29_RS09830	COG3851	Histidine kinase
B1H29_RS09860	COG2205	protein histidine kinase activity
B1H29_RS09865	COG0745	RESPONSE REGULATOR receiver
B1H29_RS09870	COG1126	abc transporter atp-binding protein
B1H29_RS09875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B1H29_RS09880	COG0765	amino acid transport
B1H29_RS09885	COG0765	amino acid transport
B1H29_RS09910	COG0628	permease
B1H29_RS09935	COG2207	Transcriptional regulator
B1H29_RS09935	COG1917	Cupin 2, conserved barrel domain protein
B1H29_RS09940	COG1201	RNA secondary structure unwinding
B1H29_RS09945	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
B1H29_RS09965	COG0783	Belongs to the Dps family
B1H29_RS09970	COG1396	sequence-specific DNA binding
B1H29_RS09975	COG1058	Belongs to the CinA family
B1H29_RS09975	COG1546	Belongs to the CinA family
B1H29_RS09985	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
B1H29_RS09995	COG1674	ftsk spoiiie
B1H29_RS10005	COG2205	protein histidine kinase activity
B1H29_RS10005	COG0784	Response regulator, receiver
B1H29_RS10015	COG2208	phosphoserine phosphatase activity
B1H29_RS10015	COG2770	Histidine kinase
B1H29_RS10050	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
B1H29_RS10055	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B1H29_RS10060	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
B1H29_RS10080	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
B1H29_RS10085	COG0612	Peptidase, M16
B1H29_RS10090	COG1185	polyribonucleotide nucleotidyltransferase activity
B1H29_RS10095	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
B1H29_RS10110	COG0455	bacterial-type flagellum organization
B1H29_RS10115	COG0747	negative chemotaxis
B1H29_RS10120	COG0601	transmembrane transport
B1H29_RS10125	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B1H29_RS10150	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
B1H29_RS10155	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
B1H29_RS10165	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
B1H29_RS10180	COG0779	Required for maturation of 30S ribosomal subunits
B1H29_RS10215	COG0442	prolyl-tRNA aminoacylation
B1H29_RS10230	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
B1H29_RS10235	COG0750	zinc metalloprotease
B1H29_RS10240	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
B1H29_RS10280	COG0395	ABC-type sugar transport system, permease component
B1H29_RS10285	COG4209	transmembrane transport
B1H29_RS10310	COG2226	methyltransferase
B1H29_RS10320	COG1012	belongs to the aldehyde dehydrogenase family
B1H29_RS10325	COG2508	Transcriptional regulator
B1H29_RS10350	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B1H29_RS10355	COG1177	transmembrane transport
B1H29_RS10360	COG1176	ABC-type spermidine putrescine transport system, permease component I
B1H29_RS10365	COG3842	ATPase activity
B1H29_RS10390	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
B1H29_RS10395	COG0584	glycerophosphoryl diester phosphodiesterase
B1H29_RS10410	COG1012	belongs to the aldehyde dehydrogenase family
B1H29_RS10420	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B1H29_RS10455	COG3842	ATPase activity
B1H29_RS10460	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
B1H29_RS10470	COG0820	rRNA (adenine-C2-)-methyltransferase activity
B1H29_RS10475	COG0575	Belongs to the CDS family
B1H29_RS10480	COG0233	cytoplasmic translational termination
B1H29_RS10485	COG0528	UMP kinase activity
B1H29_RS10490	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
B1H29_RS10495	COG0052	Belongs to the universal ribosomal protein uS2 family
B1H29_RS10510	COG1191	sigma factor activity
B1H29_RS10530	COG0792	nuclease activity
B1H29_RS10550	COG0681	Belongs to the peptidase S26 family
B1H29_RS10560	COG0681	Belongs to the peptidase S26 family
B1H29_RS10565	COG0335	large ribosomal subunit rRNA binding
B1H29_RS10570	COG0336	Belongs to the RNA methyltransferase TrmD family
B1H29_RS10575	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
B1H29_RS10580	COG1837	Belongs to the UPF0109 family
B1H29_RS10585	COG0228	four-way junction DNA binding
B1H29_RS10605	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
B1H29_RS10615	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
B1H29_RS10655	COG0477	Major facilitator Superfamily
B1H29_RS10660	COG1196	nuclear chromosome segregation
B1H29_RS10675	COG1254	Belongs to the acylphosphatase family
B1H29_RS10680	COG2340	Cysteine-rich secretory protein family
B1H29_RS10685	COG1733	regulation of RNA biosynthetic process
B1H29_RS10690	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
B1H29_RS10695	COG0571	ribonuclease III activity
B1H29_RS10700	COG0333	Belongs to the bacterial ribosomal protein bL32 family
B1H29_RS10715	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
B1H29_RS10720	COG0742	ribosomal rna small subunit methyltransferase
B1H29_RS10730	COG1461	Dihydroxyacetone kinase
B1H29_RS10735	COG0227	Belongs to the bacterial ribosomal protein bL28 family
B1H29_RS10745	COG0351	phosphomethylpyrimidine kinase
B1H29_RS10760	COG1181	Belongs to the D-alanine--D-alanine ligase family
B1H29_RS10765	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
B1H29_RS10775	COG1920	GTP binding
B1H29_RS10785	COG0776	regulation of translation
B1H29_RS10795	COG0066	3-isopropylmalate dehydratase activity
B1H29_RS10800	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
B1H29_RS10805	COG1414	Transcriptional regulator
B1H29_RS10860	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
B1H29_RS10865	COG0179	Fumarylacetoacetate (FAA) hydrolase
B1H29_RS10875	COG5002	protein histidine kinase activity
B1H29_RS10880	COG2018	Roadblock/LC7 domain
B1H29_RS10900	COG2018	Roadblock/LC7 domain
B1H29_RS10920	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B1H29_RS10930	COG1032	radical SAM domain protein
B1H29_RS10935	COG2353	YceI-like domain
B1H29_RS10965	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B1H29_RS10985	COG2957	Belongs to the agmatine deiminase family
B1H29_RS10990	COG0804	urea catabolic process
B1H29_RS10995	COG0831	urea catabolic process
B1H29_RS10995	COG0832	Belongs to the urease beta subunit family
B1H29_RS11005	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B1H29_RS11010	COG0473	3-isopropylmalate dehydrogenase activity
B1H29_RS11020	COG1012	belongs to the aldehyde dehydrogenase family
B1H29_RS11025	COG0506	proline dehydrogenase activity
B1H29_RS11030	COG2508	Transcriptional regulator
B1H29_RS11040	COG0477	Major facilitator Superfamily
B1H29_RS11045	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B1H29_RS11050	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
B1H29_RS11055	COG0440	acetolactate synthase activity
B1H29_RS11070	COG5001	Diguanylate cyclase
B1H29_RS11080	COG0667	Aldo Keto reductase
B1H29_RS11085	COG2133	pyrroloquinoline quinone binding
B1H29_RS11110	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B1H29_RS11115	COG2409	Drug exporters of the RND superfamily
B1H29_RS11120	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
B1H29_RS11130	COG0154	amidase activity
B1H29_RS11135	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
B1H29_RS11145	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
B1H29_RS11155	COG4221	oxidoreductase activity
B1H29_RS11160	COG1611	Belongs to the LOG family
B1H29_RS11175	COG0482	sulfurtransferase activity
B1H29_RS11200	COG1309	transcriptional regulator
B1H29_RS11210	COG0789	Transcriptional regulator
B1H29_RS11220	COG2860	membrane
B1H29_RS11225	COG4608	Belongs to the ABC transporter superfamily
B1H29_RS11230	COG0444	Belongs to the ABC transporter superfamily
B1H29_RS11240	COG4166	transmembrane transport
B1H29_RS11265	COG0404	The glycine cleavage system catalyzes the degradation of glycine
B1H29_RS11270	COG0509	glycine decarboxylation via glycine cleavage system
B1H29_RS11275	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
B1H29_RS11280	COG1760	l-serine dehydratase
B1H29_RS11290	COG3757	hydrolase, family 25
B1H29_RS11290	COG3409	Peptidoglycan-binding domain 1 protein
B1H29_RS11295	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B1H29_RS11320	COG1024	Enoyl-CoA hydratase
B1H29_RS11340	COG1132	(ABC) transporter
B1H29_RS11345	COG1132	(ABC) transporter
B1H29_RS11365	COG0058	SHG alpha-glucan phosphorylase activity
B1H29_RS11370	COG0366	Alpha amylase catalytic
B1H29_RS11380	COG3281	Trehalose synthase
B1H29_RS11385	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
B1H29_RS11395	COG3118	belongs to the thioredoxin family
B1H29_RS11395	COG0492	ferredoxin-NADP+ reductase activity
B1H29_RS11400	COG0789	Transcriptional regulator
B1H29_RS11405	COG1301	dicarboxylic acid transport
B1H29_RS11410	COG3290	protein histidine kinase activity
B1H29_RS11415	COG4565	transcriptional regulatory protein
B1H29_RS11420	COG1653	transport
B1H29_RS11430	COG0395	ABC-type sugar transport system, permease component
B1H29_RS11440	COG0205	6-phosphofructokinase activity
B1H29_RS11445	COG0280	phosphate acetyltransferase
B1H29_RS11445	COG0857	belongs to the CobB CobQ family
B1H29_RS11450	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
B1H29_RS11490	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
B1H29_RS11490	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
B1H29_RS11535	COG2205	protein histidine kinase activity
B1H29_RS11540	COG0745	RESPONSE REGULATOR receiver
B1H29_RS11555	COG0183	Belongs to the thiolase family
B1H29_RS11575	COG1131	(ABC) transporter
B1H29_RS11610	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
B1H29_RS11625	COG1250	3-hydroxyacyl-CoA dehydrogenase
B1H29_RS11655	COG4585	Histidine kinase
B1H29_RS11660	COG2197	response regulator
B1H29_RS11675	COG0355	proton-transporting ATP synthase activity, rotational mechanism
B1H29_RS11680	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
B1H29_RS11685	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
B1H29_RS11690	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
B1H29_RS11695	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
B1H29_RS11700	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
B1H29_RS11705	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
B1H29_RS11735	COG3321	synthase
B1H29_RS11735	COG0604	alcohol dehydrogenase
B1H29_RS11760	COG3321	synthase
B1H29_RS11760	COG0604	alcohol dehydrogenase
B1H29_RS11780	COG0604	alcohol dehydrogenase
B1H29_RS11780	COG3321	synthase
B1H29_RS11805	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
B1H29_RS11805	COG1672	PFAM Archaeal ATPase
B1H29_RS11820	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
B1H29_RS11820	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
B1H29_RS11830	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
B1H29_RS11835	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
B1H29_RS11845	COG2890	protein-(glutamine-N5) methyltransferase activity
B1H29_RS11850	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
B1H29_RS11855	COG0254	rRNA binding
B1H29_RS11860	COG1316	TRANSCRIPTIONal
B1H29_RS11875	COG0083	homoserine kinase activity
B1H29_RS11880	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
B1H29_RS11885	COG0460	homoserine dehydrogenase
B1H29_RS11890	COG0019	diaminopimelate decarboxylase activity
B1H29_RS11895	COG0018	arginyl-trna synthetase
B1H29_RS11895	COG0018	arginyl-trna synthetase
B1H29_RS11900	COG0745	RESPONSE REGULATOR receiver
B1H29_RS11925	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B1H29_RS11930	COG2329	Antibiotic biosynthesis monooxygenase
B1H29_RS11935	COG0662	Cupin 2, conserved barrel domain protein
B1H29_RS11940	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B1H29_RS11945	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B1H29_RS11950	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B1H29_RS11955	COG2867	negative regulation of translational initiation
B1H29_RS11970	COG3467	pyridoxamine 5'-phosphate
B1H29_RS11995	COG1309	transcriptional regulator
B1H29_RS12000	COG1121	(ABC) transporter
B1H29_RS12010	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
B1H29_RS12015	COG1793	dna ligase
B1H29_RS12015	COG3285	dna ligase
B1H29_RS12035	COG2205	protein histidine kinase activity
B1H29_RS12050	COG0768	penicillin binding
B1H29_RS12060	COG1309	transcriptional regulator
B1H29_RS12070	COG3883	PFAM NLP P60 protein
B1H29_RS12070	COG0791	NLP P60 protein
B1H29_RS12115	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
B1H29_RS12125	COG0745	RESPONSE REGULATOR receiver
B1H29_RS12130	COG2205	protein histidine kinase activity
B1H29_RS12135	COG0508	dehydrogenase complex catalyzes the overall conversion of
B1H29_RS12135	COG0567	Dehydrogenase, E1 component
B1H29_RS12170	COG0604	alcohol dehydrogenase
B1H29_RS12175	COG0281	malic enzyme
B1H29_RS12195	COG1126	abc transporter atp-binding protein
B1H29_RS12200	COG4106	trans-aconitate 2-methyltransferase activity
B1H29_RS12230	COG0142	geranyltranstransferase activity
B1H29_RS12235	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B1H29_RS12245	COG2515	1-aminocyclopropane-1-carboxylate deaminase
B1H29_RS12275	COG1597	lipid kinase activity
B1H29_RS12295	COG1028	Short-chain dehydrogenase reductase Sdr
B1H29_RS12300	COG0363	glucosamine-6-phosphate deaminase activity
B1H29_RS12305	COG1472	Belongs to the glycosyl hydrolase 3 family
B1H29_RS12310	COG0395	ABC-type sugar transport system, permease component
B1H29_RS12315	COG1175	transmembrane transport
B1H29_RS12320	COG2182	Extracellular solute-binding protein
B1H29_RS12325	COG2188	Transcriptional regulator
B1H29_RS12365	COG2124	cytochrome p450
B1H29_RS12375	COG0242	peptide deformylase activity
B1H29_RS12395	COG5662	AntiSigma factor
B1H29_RS12400	COG1595	DNA-templated transcription, initiation
B1H29_RS12410	COG2135	peptidase activity
B1H29_RS12420	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
B1H29_RS12430	COG2076	Multidrug Resistance protein
B1H29_RS12440	COG0483	inositol monophosphate 1-phosphatase activity
B1H29_RS12450	COG0753	catalase activity
B1H29_RS12475	COG1615	UPF0182 protein
B1H29_RS12485	COG3480	Lon protease (S16) C-terminal proteolytic domain
B1H29_RS12535	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
B1H29_RS12565	COG2816	NAD+ diphosphatase activity
B1H29_RS12575	COG0210	DNA helicase
B1H29_RS12585	COG0210	DNA helicase
B1H29_RS12605	COG0596	Alpha beta hydrolase
B1H29_RS12685	COG2267	carboxylic ester hydrolase activity
B1H29_RS12690	COG1432	Conserved Protein
B1H29_RS12700	COG2095	MarC family integral membrane protein
B1H29_RS12705	COG0613	PHP domain protein
B1H29_RS12715	COG2814	Major facilitator Superfamily
B1H29_RS12725	COG0598	Magnesium transport protein CorA
B1H29_RS12735	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
B1H29_RS12760	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B1H29_RS12765	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B1H29_RS12775	COG1595	DNA-templated transcription, initiation
B1H29_RS12790	COG1024	Enoyl-CoA hydratase
B1H29_RS12795	COG0519	Catalyzes the synthesis of GMP from XMP
B1H29_RS12805	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
B1H29_RS12815	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B1H29_RS12865	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
B1H29_RS12900	COG4608	Belongs to the ABC transporter superfamily
B1H29_RS12905	COG0444	Belongs to the ABC transporter superfamily
B1H29_RS12910	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B1H29_RS12915	COG0601	transmembrane transport
B1H29_RS12925	COG4608	Belongs to the ABC transporter superfamily
B1H29_RS12930	COG0444	Belongs to the ABC transporter superfamily
B1H29_RS12940	COG0747	negative chemotaxis
B1H29_RS12945	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B1H29_RS12950	COG1217	gtp-binding protein TYPA
B1H29_RS12975	COG1053	succinate dehydrogenase
B1H29_RS12980	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
B1H29_RS13040	COG2813	Specifically methylates the guanine in position
B1H29_RS13045	COG2318	DinB family
B1H29_RS13050	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B1H29_RS13090	COG0515	serine threonine protein kinase
B1H29_RS13140	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
B1H29_RS13185	COG0012	GTP binding
B1H29_RS13200	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
B1H29_RS13210	COG1570	exodeoxyribonuclease VII activity
B1H29_RS13215	COG1722	exodeoxyribonuclease VII activity
B1H29_RS13225	COG0778	Nitroreductase
B1H29_RS13230	COG2826	transposase and inactivated derivatives, IS30 family
B1H29_RS13255	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
B1H29_RS13255	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
B1H29_RS13260	COG0114	fumarate hydratase activity
B1H29_RS13275	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B1H29_RS13295	COG1136	(ABC) transporter
B1H29_RS13310	COG0450	alkyl hydroperoxide reductase
B1H29_RS13315	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B1H29_RS13330	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
B1H29_RS13345	COG2226	methyltransferase
B1H29_RS13440	COG2894	cell division
B1H29_RS13475	COG2610	gluconate transmembrane transporter activity
B1H29_RS13480	COG0251	oxidation-reduction process
B1H29_RS13485	COG1414	Transcriptional regulator
B1H29_RS13500	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
B1H29_RS13515	COG0436	Aminotransferase
B1H29_RS13530	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
B1H29_RS13540	COG1309	transcriptional regulator
B1H29_RS13575	COG1331	Highly conserved protein containing a thioredoxin domain
B1H29_RS13580	COG0583	DNA-binding transcription factor activity
B1H29_RS13585	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B1H29_RS13595	COG2610	gluconate transmembrane transporter activity
B1H29_RS13600	COG0590	tRNA wobble adenosine to inosine editing
B1H29_RS13610	COG1529	Aldehyde oxidase and xanthine dehydrogenase
B1H29_RS13630	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
B1H29_RS13640	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
B1H29_RS13655	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
B1H29_RS13660	COG2255	four-way junction helicase activity
B1H29_RS13685	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B1H29_RS13700	COG0667	Aldo Keto reductase
B1H29_RS13705	COG1090	epimerase
B1H29_RS13710	COG1064	alcohol dehydrogenase
B1H29_RS13730	COG2986	histidine ammonia-lyase
B1H29_RS13740	COG1024	Enoyl-CoA hydratase
B1H29_RS13750	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
B1H29_RS13760	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B1H29_RS13775	COG0424	maF-like protein
B1H29_RS13785	COG4770	biotin carboxylase activity
B1H29_RS13810	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B1H29_RS13830	COG1012	belongs to the aldehyde dehydrogenase family
B1H29_RS13835	COG1012	belongs to the aldehyde dehydrogenase family
B1H29_RS13850	COG1595	DNA-templated transcription, initiation
B1H29_RS13855	COG0745	RESPONSE REGULATOR receiver
B1H29_RS13860	COG2205	protein histidine kinase activity
B1H29_RS13885	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
B1H29_RS13895	COG0583	DNA-binding transcription factor activity
B1H29_RS13900	COG2814	Major facilitator Superfamily
B1H29_RS13935	COG1079	Belongs to the binding-protein-dependent transport system permease family
B1H29_RS13945	COG3845	ABC transporter
B1H29_RS13950	COG1744	ABC transporter substrate-binding protein PnrA-like
B1H29_RS13955	COG1744	ABC transporter substrate-binding protein PnrA-like
B1H29_RS13960	COG1473	amidohydrolase
B1H29_RS13960	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
B1H29_RS13970	COG2089	acid synthase
B1H29_RS13990	COG1216	Glycosyl transferase, family 2
B1H29_RS14000	COG1216	Glycosyl transferase, family 2
B1H29_RS14035	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
B1H29_RS14035	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
B1H29_RS14050	COG1595	DNA-templated transcription, initiation
B1H29_RS14060	COG1595	DNA-templated transcription, initiation
B1H29_RS14095	COG2009	succinate dehydrogenase
B1H29_RS14105	COG1053	succinate dehydrogenase
B1H29_RS14145	COG1309	transcriptional regulator
B1H29_RS14150	COG1408	metallophosphoesterase
B1H29_RS14160	COG1686	Belongs to the peptidase S11 family
B1H29_RS14165	COG1295	ribonuclease BN
B1H29_RS14180	COG0671	phosphoesterase, PA-phosphatase related
B1H29_RS14200	COG0180	Tryptophanyl-tRNA synthetase
B1H29_RS14205	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
B1H29_RS14210	COG0754	glutathionylspermidine amidase activity
B1H29_RS14220	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B1H29_RS14225	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B1H29_RS14240	COG4176	ABC-type proline glycine betaine transport system permease component
B1H29_RS14245	COG0517	IMP dehydrogenase activity
B1H29_RS14245	COG4175	Glycine betaine
B1H29_RS14255	COG1012	belongs to the aldehyde dehydrogenase family
B1H29_RS14260	COG0456	acetyltransferase
B1H29_RS14260	COG1846	Transcriptional regulator
B1H29_RS14265	COG0039	L-malate dehydrogenase activity
B1H29_RS14285	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
B1H29_RS14300	COG0515	serine threonine protein kinase
B1H29_RS14315	COG0515	serine threonine protein kinase
B1H29_RS14315	COG2815	serine threonine protein kinase
B1H29_RS14330	COG0138	bifunctional purine biosynthesis protein purh
B1H29_RS14360	COG0045	succinate-CoA ligase (ADP-forming) activity
B1H29_RS14370	COG3552	Protein containing von Willebrand factor type A (VWA) domain
B1H29_RS14375	COG2425	protein containing a von Willebrand factor type A (vWA) domain
B1H29_RS14380	COG0714	Associated with various cellular activities
B1H29_RS14395	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
B1H29_RS14395	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
B1H29_RS14405	COG0739	heme binding
B1H29_RS14435	COG2197	response regulator
B1H29_RS14495	COG0518	GMP synthase (glutamine-hydrolyzing) activity
B1H29_RS14495	COG0519	Catalyzes the synthesis of GMP from XMP
B1H29_RS14520	COG1012	belongs to the aldehyde dehydrogenase family
B1H29_RS14525	COG0515	serine threonine protein kinase
B1H29_RS14530	COG0515	serine threonine protein kinase
B1H29_RS14540	COG0515	serine threonine protein kinase
B1H29_RS14545	COG0515	serine threonine protein kinase
B1H29_RS14545	COG2815	serine threonine protein kinase
B1H29_RS14555	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
B1H29_RS14565	COG0516	GMP reductase activity
B1H29_RS14575	COG1595	DNA-templated transcription, initiation
B1H29_RS14590	COG0583	DNA-binding transcription factor activity
B1H29_RS14600	COG4221	oxidoreductase activity
B1H29_RS14625	COG0459	protein refolding
B1H29_RS14630	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
B1H29_RS14635	COG0726	polysaccharide deacetylase
B1H29_RS14640	COG0726	polysaccharide deacetylase
B1H29_RS14650	COG4941	Belongs to the sigma-70 factor family
B1H29_RS14675	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
B1H29_RS14685	COG0456	acetyltransferase
B1H29_RS14685	COG1214	PFAM Peptidase M22, glycoprotease
B1H29_RS14700	COG0802	atpase or kinase
B1H29_RS14710	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
B1H29_RS14715	COG0736	holo-[acyl-carrier-protein] synthase activity
B1H29_RS14765	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
B1H29_RS14775	COG1072	(Pantothenic acid kinase))
B1H29_RS14790	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B1H29_RS14795	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
B1H29_RS14800	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
B1H29_RS14815	COG0101	tRNA pseudouridine synthase activity
B1H29_RS14820	COG0203	ribosomal protein L17
B1H29_RS14825	COG0202	RNA polymerase activity
B1H29_RS14830	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
B1H29_RS14835	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
B1H29_RS14840	COG0257	Belongs to the bacterial ribosomal protein bL36 family
B1H29_RS14845	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
B1H29_RS14855	COG0563	adenylate kinase activity
B1H29_RS14860	COG0201	protein transport
B1H29_RS14865	COG0200	Binds to the 23S rRNA
B1H29_RS14870	COG1841	ribosomal large subunit assembly
B1H29_RS14875	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
B1H29_RS14880	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
B1H29_RS14885	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
B1H29_RS14890	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
B1H29_RS14900	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
B1H29_RS14905	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
B1H29_RS14910	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
B1H29_RS14915	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
B1H29_RS14920	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
B1H29_RS14925	COG0255	Belongs to the universal ribosomal protein uL29 family
B1H29_RS14930	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
B1H29_RS14935	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
B1H29_RS14940	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
B1H29_RS14945	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
B1H29_RS14950	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
B1H29_RS14955	COG0089	rRNA binding
B1H29_RS14960	COG0088	Forms part of the polypeptide exit tunnel
B1H29_RS14965	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
B1H29_RS14970	COG0051	transcription antitermination factor activity, RNA binding
B1H29_RS14980	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
B1H29_RS14990	COG1028	Short-chain dehydrogenase reductase Sdr
B1H29_RS15020	COG0583	DNA-binding transcription factor activity
B1H29_RS15035	COG2197	response regulator
B1H29_RS15045	COG0577	efflux transmembrane transporter activity
B1H29_RS15045	COG1136	(ABC) transporter
B1H29_RS15050	COG0577	efflux transmembrane transporter activity
B1H29_RS15055	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
B1H29_RS15060	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
B1H29_RS15065	COG0049	tRNA binding
B1H29_RS15070	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
B1H29_RS15075	COG0463	Glycosyl transferase, family 2
B1H29_RS15085	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
B1H29_RS15090	COG0085	RNA polymerase activity
B1H29_RS15100	COG0222	ribosome binding
B1H29_RS15105	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
B1H29_RS15120	COG0081	regulation of translation
B1H29_RS15125	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
B1H29_RS15130	COG0250	Participates in transcription elongation, termination and antitermination
B1H29_RS15145	COG0436	Aminotransferase
B1H29_RS15150	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
B1H29_RS15165	COG0812	UDP-N-acetylmuramate dehydrogenase activity
B1H29_RS15175	COG0477	Major facilitator Superfamily
B1H29_RS15195	COG2030	dehydratase
B1H29_RS15200	COG0267	Belongs to the bacterial ribosomal protein bL33 family
B1H29_RS15215	COG0402	S-adenosylhomocysteine deaminase activity
B1H29_RS15220	COG0702	epimerase
B1H29_RS15235	COG1666	GTP binding
B1H29_RS15240	COG2261	transglycosylase associated protein
B1H29_RS15250	COG3304	Inner membrane component domain
B1H29_RS15255	COG0501	Belongs to the peptidase M48B family
B1H29_RS15260	COG1007	ATP synthesis coupled electron transport
B1H29_RS15270	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
B1H29_RS15275	COG0713	ATP synthesis coupled electron transport
B1H29_RS15285	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B1H29_RS15290	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
B1H29_RS15295	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B1H29_RS15300	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B1H29_RS15305	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B1H29_RS15325	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
B1H29_RS15325	COG0674	pyruvate-flavodoxin oxidoreductase activity
B1H29_RS15330	COG1013	pyruvate-flavodoxin oxidoreductase activity
B1H29_RS15335	COG0702	epimerase
B1H29_RS15390	COG0142	geranyltranstransferase activity
B1H29_RS15400	COG0561	phosphatase activity
B1H29_RS15460	COG0514	ATP-dependent DNA helicase (RecQ)
B1H29_RS15470	COG1007	ATP synthesis coupled electron transport
B1H29_RS15480	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
B1H29_RS15485	COG0713	ATP synthesis coupled electron transport
B1H29_RS15495	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B1H29_RS15500	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
B1H29_RS15505	COG1034	ATP synthesis coupled electron transport
B1H29_RS15510	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
B1H29_RS15520	COG0649	NAD binding
B1H29_RS15525	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B1H29_RS15530	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B1H29_RS15545	COG0242	peptide deformylase activity
B1H29_RS15565	COG2226	methyltransferase
B1H29_RS15575	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
B1H29_RS15640	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
B1H29_RS15760	COG1674	ftsk spoiiie
B1H29_RS15770	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
B1H29_RS15775	COG1278	Cold shock
B1H29_RS15790	COG0183	Belongs to the thiolase family
B1H29_RS15805	COG1309	transcriptional regulator
B1H29_RS15810	COG1301	dicarboxylic acid transport
B1H29_RS15825	COG1573	uracil-dna glycosylase
B1H29_RS15830	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
B1H29_RS15840	COG0163	prenyltransferase activity
B1H29_RS15845	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
B1H29_RS15850	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
B1H29_RS15860	COG0515	serine threonine protein kinase
B1H29_RS15860	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B1H29_RS15865	COG0515	serine threonine protein kinase
B1H29_RS15865	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B1H29_RS15890	COG0789	Transcriptional regulator
B1H29_RS15900	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
B1H29_RS15905	COG1333	cytochrome c biogenesis protein
B1H29_RS15910	COG0785	Cytochrome C biogenesis protein
B1H29_RS15915	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B1H29_RS15925	COG0406	alpha-ribazole phosphatase activity
B1H29_RS15930	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
B1H29_RS15965	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
B1H29_RS15995	COG1115	amino acid carrier protein
B1H29_RS16000	COG2255	four-way junction helicase activity
B1H29_RS16010	COG0431	NADPH-dependent FMN reductase
B1H29_RS16015	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B1H29_RS16020	COG1742	UPF0060 membrane protein
B1H29_RS16045	COG1690	Belongs to the RtcB family
B1H29_RS16090	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
B1H29_RS16095	COG0018	arginyl-trna synthetase
B1H29_RS16120	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B1H29_RS16140	COG0113	porphobilinogen synthase activity
B1H29_RS16160	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
B1H29_RS16160	COG1648	precorrin-2 dehydrogenase activity
B1H29_RS16165	COG0181	hydroxymethylbilane synthase activity
B1H29_RS16170	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
B1H29_RS16175	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
B1H29_RS16225	COG0123	including yeast histone deacetylase and acetoin utilization protein
B1H29_RS16230	COG2223	nitrite transmembrane transporter activity
B1H29_RS16260	COG0180	Tryptophanyl-tRNA synthetase
B1H29_RS16275	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
B1H29_RS16285	COG1129	ABC transporter
B1H29_RS16285	COG0842	Transport permease protein
B1H29_RS16305	COG4991	sh3 domain protein
B1H29_RS16310	COG0515	serine threonine protein kinase
B1H29_RS16310	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B1H29_RS16315	COG0129	dihydroxy-acid dehydratase activity
B1H29_RS16320	COG1309	transcriptional regulator
B1H29_RS16325	COG1082	Xylose isomerase domain protein TIM barrel
B1H29_RS16330	COG0248	Ppx GppA phosphatase
B1H29_RS16355	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
B1H29_RS16375	COG2197	response regulator
B1H29_RS16380	COG4585	Histidine kinase
B1H29_RS16385	COG1194	a g-specific adenine glycosylase
B1H29_RS16390	COG1595	DNA-templated transcription, initiation
B1H29_RS16400	COG0745	RESPONSE REGULATOR receiver
B1H29_RS16405	COG2205	protein histidine kinase activity
B1H29_RS16410	COG0346	lactoylglutathione lyase activity
B1H29_RS16435	COG2226	methyltransferase
B1H29_RS16450	COG0739	heme binding
B1H29_RS16495	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
B1H29_RS16515	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
B1H29_RS16525	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
B1H29_RS16530	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
B1H29_RS16560	COG1660	Displays ATPase and GTPase activities
B1H29_RS16565	COG2197	response regulator
B1H29_RS16580	COG0649	NAD binding
B1H29_RS16620	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
B1H29_RS16635	COG0302	gtp cyclohydrolase
B1H29_RS16650	COG0037	tRNA processing
B1H29_RS16660	COG2027	D-alanyl-D-alanine carboxypeptidase
B1H29_RS16665	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
B1H29_RS16675	COG0586	Pfam SNARE associated Golgi protein
B1H29_RS16680	COG0393	Putative heavy-metal-binding
B1H29_RS16685	COG0789	Transcriptional regulator
B1H29_RS16690	COG0076	glutamate decarboxylase activity
B1H29_RS16710	COG2318	DinB family
B1H29_RS16715	COG1012	belongs to the aldehyde dehydrogenase family
B1H29_RS16740	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
B1H29_RS16750	COG0254	rRNA binding
B1H29_RS16755	COG0267	Belongs to the bacterial ribosomal protein bL33 family
B1H29_RS16760	COG0227	Belongs to the bacterial ribosomal protein bL28 family
B1H29_RS16765	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
B1H29_RS16785	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B1H29_RS16785	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B1H29_RS16795	COG3903	Transcriptional regulator
B1H29_RS16795	COG3629	intracellular signal transduction
B1H29_RS16810	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
B1H29_RS16830	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
B1H29_RS16835	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
B1H29_RS16835	COG1754	DNA topoisomerase type I activity
B1H29_RS16855	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
B1H29_RS16860	COG2172	sigma factor antagonist activity
B1H29_RS16865	COG1366	Belongs to the anti-sigma-factor antagonist family
B1H29_RS16870	COG1111	helicase
B1H29_RS16870	COG1205	dead DEAH box helicase
B1H29_RS16935	COG0659	secondary active sulfate transmembrane transporter activity
B1H29_RS16940	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B1H29_RS16945	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
B1H29_RS16955	COG0596	Alpha beta hydrolase
B1H29_RS16985	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B1H29_RS16995	COG0596	Alpha beta hydrolase
B1H29_RS17000	COG0251	oxidation-reduction process
B1H29_RS17015	COG0003	Pfam Anion-transporting ATPase
B1H29_RS17030	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B1H29_RS17040	COG1408	metallophosphoesterase
B1H29_RS17065	COG1695	Transcriptional regulator
B1H29_RS17105	COG3263	regulation of cellular component size
B1H29_RS17125	COG3655	Transcriptional regulator
B1H29_RS17140	COG2268	Band 7 protein
B1H29_RS17145	COG1585	Membrane protein implicated in regulation of membrane protease activity
B1H29_RS17210	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
B1H29_RS17215	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
B1H29_RS17235	COG0693	protein deglycase activity
B1H29_RS17240	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B1H29_RS17245	COG1802	Transcriptional regulator
B1H29_RS17275	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
B1H29_RS17290	COG1131	(ABC) transporter
B1H29_RS17295	COG3559	Exporter of polyketide antibiotics
B1H29_RS17335	COG2197	response regulator
B1H29_RS17340	COG4585	Histidine kinase
B1H29_RS17345	COG2197	response regulator
B1H29_RS17350	COG4585	Histidine kinase
B1H29_RS17370	COG3844	kynureninase activity
B1H29_RS17375	COG3483	tryptophan 2,3-dioxygenase activity
B1H29_RS17385	COG0191	fructose-bisphosphate aldolase activity
B1H29_RS17390	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
B1H29_RS17405	COG2197	response regulator
B1H29_RS17410	COG4585	Histidine kinase
B1H29_RS17415	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
B1H29_RS17445	COG0542	response to heat
B1H29_RS17470	COG4213	ABC transporter substrate-binding protein
B1H29_RS17475	COG0789	Transcriptional regulator
B1H29_RS17480	COG0484	heat shock protein binding
B1H29_RS17485	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
B1H29_RS17490	COG0443	Heat shock 70 kDa protein
B1H29_RS17495	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
B1H29_RS17500	COG2181	nitrate reductase activity
B1H29_RS17500	COG0247	lactate metabolic process
B1H29_RS17525	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
B1H29_RS17530	COG0717	Belongs to the dCTP deaminase family
B1H29_RS17550	COG1136	(ABC) transporter
B1H29_RS17550	COG4591	ABC-type transport system involved in lipoprotein release permease component
B1H29_RS17565	COG1396	sequence-specific DNA binding
B1H29_RS17570	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
B1H29_RS17590	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B1H29_RS17610	COG0640	Transcriptional regulator
B1H29_RS17615	COG2072	flavoprotein involved in K transport
B1H29_RS17625	COG0798	PFAM Bile acid sodium symporter
B1H29_RS17630	COG0640	Transcriptional regulator
B1H29_RS17635	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
B1H29_RS17640	COG0492	ferredoxin-NADP+ reductase activity
B1H29_RS17645	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
B1H29_RS17685	COG0596	Alpha beta hydrolase
B1H29_RS17705	COG1595	DNA-templated transcription, initiation
B1H29_RS17725	COG1278	Cold shock
B1H29_RS17765	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
B1H29_RS17770	COG5002	protein histidine kinase activity
B1H29_RS17775	COG0745	RESPONSE REGULATOR receiver
B1H29_RS17815	COG1278	Cold shock
B1H29_RS17840	COG4585	Histidine kinase
B1H29_RS17850	COG0577	efflux transmembrane transporter activity
B1H29_RS17850	COG1136	(ABC) transporter
B1H29_RS17885	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
B1H29_RS17915	COG1309	transcriptional regulator
B1H29_RS17935	COG0583	DNA-binding transcription factor activity
B1H29_RS17965	COG0366	Alpha amylase catalytic
B1H29_RS17970	COG1957	nucleoside hydrolase
B1H29_RS17975	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
B1H29_RS17995	COG0701	Predicted permease
B1H29_RS18010	COG1653	transport
B1H29_RS18065	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B1H29_RS18085	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
B1H29_RS18105	COG1136	(ABC) transporter
B1H29_RS18130	COG1741	Belongs to the pirin family
B1H29_RS18140	COG1960	acyl-CoA dehydrogenase activity
B1H29_RS18145	COG1362	aminopeptidase activity
B1H29_RS18200	COG0508	dehydrogenase complex catalyzes the overall conversion of
B1H29_RS18205	COG0022	dehydrogenase e1 component
B1H29_RS18225	COG0515	serine threonine protein kinase
B1H29_RS18230	COG0515	serine threonine protein kinase
B1H29_RS18245	COG3321	synthase
B1H29_RS18245	COG1028	Short-chain dehydrogenase reductase Sdr
B1H29_RS18245	COG0604	alcohol dehydrogenase
B1H29_RS18290	COG1522	sequence-specific DNA binding
B1H29_RS18295	COG1309	transcriptional regulator
B1H29_RS18300	COG1250	3-hydroxyacyl-CoA dehydrogenase
B1H29_RS18350	COG1716	ATPase activity
B1H29_RS18355	COG1716	ATPase activity
B1H29_RS18370	COG0768	penicillin binding
B1H29_RS18380	COG0515	serine threonine protein kinase
B1H29_RS18385	COG2826	transposase and inactivated derivatives, IS30 family
B1H29_RS18390	COG3764	Sortase (surface protein transpeptidase)
B1H29_RS18395	COG3764	Sortase (surface protein transpeptidase)
B1H29_RS18420	COG0705	Rhomboid family
B1H29_RS18435	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
B1H29_RS18445	COG0745	RESPONSE REGULATOR receiver
B1H29_RS18460	COG0515	serine threonine protein kinase
B1H29_RS18485	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
B1H29_RS18495	COG2319	Wd-40 repeat
B1H29_RS18495	COG4249	Peptidase C14 caspase catalytic subunit p20
B1H29_RS18520	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
B1H29_RS18525	COG0187	DNA topoisomerase II activity
B1H29_RS18530	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
B1H29_RS18535	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
B1H29_RS18540	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
B1H29_RS18545	COG0592	DNA-directed DNA polymerase activity
B1H29_RS18555	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
B1H29_RS18560	COG0230	Belongs to the bacterial ribosomal protein bL34 family
B1H29_RS18565	COG0594	ribonuclease P activity
B1H29_RS18570	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
B1H29_RS18575	COG0706	membrane insertase activity
B1H29_RS18585	COG0357	Ribosomal RNA small subunit methyltransferase G
B1H29_RS18590	COG1192	Involved in chromosome partitioning
B1H29_RS18605	COG3118	belongs to the thioredoxin family
B1H29_RS18610	COG0492	ferredoxin-NADP+ reductase activity
B1H29_RS18620	COG1595	DNA-templated transcription, initiation
B1H29_RS18640	COG0617	tRNA 3'-terminal CCA addition
B1H29_RS18655	COG1260	myo-inositol-1-phosphate synthase
B1H29_RS18665	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B1H29_RS18690	COG0360	Binds together with S18 to 16S ribosomal RNA
B1H29_RS18695	COG0629	single-stranded DNA binding
B1H29_RS18700	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
B1H29_RS18705	COG0359	binds to the 23S rRNA
B1H29_RS18715	COG0305	Participates in initiation and elongation during chromosome replication
B1H29_RS18735	COG2814	Major facilitator Superfamily
B1H29_RS18760	COG0626	cystathionine gamma-synthase activity
B1H29_RS18765	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
B1H29_RS18770	COG1950	PFAM Membrane protein of
B1H29_RS18775	COG0662	Cupin 2, conserved barrel domain protein
B1H29_RS18800	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
B1H29_RS18810	COG1733	regulation of RNA biosynthetic process
B1H29_RS18825	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
B1H29_RS18830	COG1609	Transcriptional regulator
B1H29_RS18835	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
B1H29_RS18845	COG1271	oxidase subunit
B1H29_RS18850	COG1294	oxidase, subunit
B1H29_RS18855	COG4988	ABC transporter
B1H29_RS18865	COG0739	heme binding
B1H29_RS18870	COG0561	phosphatase activity
B1H29_RS18885	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
B1H29_RS18900	COG1131	(ABC) transporter
B1H29_RS18925	COG0561	phosphatase activity
B1H29_RS18930	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
B1H29_RS18940	COG2837	iron assimilation
B1H29_RS18955	COG1999	signal sequence binding
B1H29_RS18980	COG0006	proline dipeptidase activity
B1H29_RS19015	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B1H29_RS19060	COG1595	DNA-templated transcription, initiation
B1H29_RS19065	COG0318	PFAM AMP-dependent synthetase and ligase
B1H29_RS19070	COG2814	Major facilitator Superfamily
B1H29_RS19075	COG1309	transcriptional regulator
B1H29_RS19080	COG0784	Response regulator, receiver
B1H29_RS19100	COG0768	penicillin binding
B1H29_RS19105	COG1733	regulation of RNA biosynthetic process
B1H29_RS19120	COG0745	RESPONSE REGULATOR receiver
B1H29_RS19125	COG2205	protein histidine kinase activity
B1H29_RS19135	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
B1H29_RS19140	COG0477	Major facilitator Superfamily
B1H29_RS19150	COG3467	pyridoxamine 5'-phosphate
B1H29_RS19175	COG0477	Major facilitator Superfamily
B1H29_RS19190	COG1191	sigma factor activity
B1H29_RS19195	COG1191	sigma factor activity
B1H29_RS19230	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
B1H29_RS19390	COG0151	Belongs to the GarS family
B1H29_RS19405	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
B1H29_RS19415	COG2197	response regulator
B1H29_RS19450	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
B1H29_RS19455	COG0047	phosphoribosylformylglycinamidine synthase activity
B1H29_RS19460	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
B1H29_RS19500	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
B1H29_RS19535	COG1643	Atp-dependent helicase
B1H29_RS19570	COG0513	Belongs to the DEAD box helicase family
B1H29_RS19630	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
B1H29_RS19695	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B1H29_RS19695	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B1H29_RS19725	COG0220	tRNA (guanine-N7-)-methyltransferase activity
B1H29_RS19730	COG0579	oxidoreductase
B1H29_RS19750	COG1252	NADH dehydrogenase
B1H29_RS19790	COG2197	response regulator
B1H29_RS19795	COG4585	Histidine kinase
B1H29_RS19835	COG1196	nuclear chromosome segregation
B1H29_RS19835	COG0739	heme binding
B1H29_RS19835	COG0741	lytic transglycosylase activity
B1H29_RS19840	COG0671	phosphoesterase, PA-phosphatase related
B1H29_RS19855	COG1937	Protein conserved in bacteria
B1H29_RS19865	COG0306	phosphate transporter
B1H29_RS19870	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
B1H29_RS19890	COG0406	alpha-ribazole phosphatase activity
B1H29_RS19890	COG0494	nUDIX hydrolase
B1H29_RS19900	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
B1H29_RS19930	COG0456	acetyltransferase
B1H29_RS19935	COG0737	Belongs to the 5'-nucleotidase family
B1H29_RS19950	COG0745	RESPONSE REGULATOR receiver
B1H29_RS19955	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B1H29_RS19960	COG1609	Transcriptional regulator
B1H29_RS19965	COG0745	RESPONSE REGULATOR receiver
B1H29_RS19995	COG2897	thiosulfate sulfurtransferase activity
B1H29_RS20055	COG3485	protocatechuate 3,4-dioxygenase
B1H29_RS20060	COG0735	belongs to the Fur family
B1H29_RS20065	COG0404	The glycine cleavage system catalyzes the degradation of glycine
B1H29_RS20070	COG1490	D-aminoacyl-tRNA deacylase activity
B1H29_RS20085	COG4552	Acetyltransferase involved in intracellular survival and related
B1H29_RS20095	COG2188	Transcriptional regulator
B1H29_RS20105	COG2186	Transcriptional regulator
B1H29_RS20110	COG0546	phosphoglycolate phosphatase activity
B1H29_RS20120	COG2186	Transcriptional regulator
B1H29_RS20150	COG1733	regulation of RNA biosynthetic process
B1H29_RS20185	COG0438	transferase activity, transferring glycosyl groups
B1H29_RS20215	COG0588	phosphoglycerate mutase activity
B1H29_RS20220	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
B1H29_RS20245	COG2188	Transcriptional regulator
B1H29_RS20255	COG0438	transferase activity, transferring glycosyl groups
B1H29_RS20280	COG5002	protein histidine kinase activity
B1H29_RS20300	COG1329	Transcriptional regulator
B1H29_RS20310	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
B1H29_RS20315	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
B1H29_RS20320	COG0215	cysteine-tRNA ligase activity
B1H29_RS20325	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B1H29_RS20345	COG3842	ATPase activity
B1H29_RS20430	COG0464	growth
B1H29_RS20490	COG1309	transcriptional regulator
B1H29_RS20495	COG1064	alcohol dehydrogenase
B1H29_RS20520	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
B1H29_RS20535	COG5001	Diguanylate cyclase
B1H29_RS20535	COG3300	MHYT domain
B1H29_RS20550	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
B1H29_RS20590	COG0463	Glycosyl transferase, family 2
B1H29_RS20605	COG1278	Cold shock
B1H29_RS20610	COG0459	protein refolding
B1H29_RS20625	COG1595	DNA-templated transcription, initiation
B1H29_RS20655	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B1H29_RS20655	COG1263	PTS System
B1H29_RS20660	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
B1H29_RS20665	COG1737	Transcriptional regulator
B1H29_RS20705	COG3973	AAA domain
B1H29_RS20720	COG1061	Type III restriction enzyme res subunit
B1H29_RS20765	COG1278	Cold shock
B1H29_RS20770	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
B1H29_RS20775	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
B1H29_RS20785	COG2814	Major facilitator Superfamily
B1H29_RS20800	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
B1H29_RS20810	COG2252	PERMEase
B1H29_RS20840	COG0667	Aldo Keto reductase
B1H29_RS20875	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
B1H29_RS20880	COG0277	FAD linked oxidase domain protein
B1H29_RS20880	COG0247	lactate metabolic process
B1H29_RS20905	COG2318	DinB family
B1H29_RS20925	COG0515	serine threonine protein kinase
B1H29_RS20925	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B1H29_RS20940	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B1H29_RS20955	COG0318	PFAM AMP-dependent synthetase and ligase
B1H29_RS20960	COG1024	Enoyl-CoA hydratase
B1H29_RS20975	COG0259	pyridoxamine-phosphate oxidase activity
B1H29_RS20990	COG4821	SIS domain
B1H29_RS21000	COG2945	thiolester hydrolase activity
B1H29_RS21000	COG0596	Alpha beta hydrolase
B1H29_RS21050	COG1595	DNA-templated transcription, initiation
B1H29_RS21055	COG1366	Belongs to the anti-sigma-factor antagonist family
B1H29_RS21080	COG2271	Major facilitator Superfamily
B1H29_RS21090	COG2072	flavoprotein involved in K transport
B1H29_RS21100	COG0259	pyridoxamine-phosphate oxidase activity
B1H29_RS21110	COG1280	lysine exporter protein (LysE YggA)
B1H29_RS21115	COG1522	sequence-specific DNA binding
B1H29_RS21120	COG1309	transcriptional regulator
B1H29_RS21135	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B1H29_RS21135	COG0515	serine threonine protein kinase
B1H29_RS21145	COG3629	intracellular signal transduction
B1H29_RS21145	COG3903	Transcriptional regulator
B1H29_RS21165	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
B1H29_RS21190	COG0583	DNA-binding transcription factor activity
B1H29_RS21215	COG1686	Belongs to the peptidase S11 family
B1H29_RS21240	COG0386	Belongs to the glutathione peroxidase family
B1H29_RS21245	COG2208	phosphoserine phosphatase activity
B1H29_RS21255	COG0110	maltose O-acetyltransferase activity
B1H29_RS21265	COG1309	transcriptional regulator
B1H29_RS21280	COG1335	isochorismatase
B1H29_RS21285	COG0829	nickel cation binding
B1H29_RS21290	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
B1H29_RS21295	COG0830	nickel cation binding
B1H29_RS21300	COG0804	urea catabolic process
B1H29_RS21305	COG0832	Belongs to the urease beta subunit family
B1H29_RS21305	COG0831	urea catabolic process
B1H29_RS21345	COG2814	Major facilitator Superfamily
B1H29_RS21370	COG1414	Transcriptional regulator
B1H29_RS21390	COG1846	Transcriptional regulator
B1H29_RS21395	COG1247	-acetyltransferase
B1H29_RS21400	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
B1H29_RS21415	COG0477	Major facilitator Superfamily
B1H29_RS21420	COG1349	DNA-binding transcription factor activity
B1H29_RS21430	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B1H29_RS21430	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B1H29_RS21430	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
B1H29_RS21440	COG1376	ErfK ybiS ycfS ynhG family protein
B1H29_RS21445	COG3191	aminopeptidase activity
B1H29_RS21460	COG1970	mechanosensitive ion channel activity
B1H29_RS21470	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
B1H29_RS21495	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
B1H29_RS21500	COG1210	Utp--glucose-1-phosphate uridylyltransferase
B1H29_RS21510	COG0315	cyclic pyranopterin monophosphate synthase activity
B1H29_RS21515	COG0315	cyclic pyranopterin monophosphate synthase activity
B1H29_RS21515	COG0521	Mo-molybdopterin cofactor biosynthetic process
B1H29_RS21520	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B1H29_RS21545	COG0708	Exodeoxyribonuclease III
B1H29_RS21560	COG2072	flavoprotein involved in K transport
B1H29_RS21565	COG2267	carboxylic ester hydrolase activity
B1H29_RS21570	COG1028	Short-chain dehydrogenase reductase Sdr
B1H29_RS21580	COG0793	Belongs to the peptidase S41A family
B1H29_RS21580	COG4946	Tricorn protease homolog
B1H29_RS21590	COG2409	Drug exporters of the RND superfamily
B1H29_RS21595	COG0442	prolyl-tRNA aminoacylation
B1H29_RS21610	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B1H29_RS21615	COG1122	ATPase activity
B1H29_RS21625	COG0310	cobalt ion transport
B1H29_RS21640	COG0768	penicillin binding
B1H29_RS21660	COG0084	hydrolase, TatD family'
B1H29_RS21670	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
B1H29_RS21675	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
B1H29_RS21680	COG0488	(ABC) transporter
B1H29_RS21720	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
B1H29_RS21740	COG2197	response regulator
B1H29_RS21750	COG4106	trans-aconitate 2-methyltransferase activity
B1H29_RS21765	COG1309	transcriptional regulator
B1H29_RS21775	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
B1H29_RS21780	COG2826	transposase and inactivated derivatives, IS30 family
B1H29_RS21790	COG0193	aminoacyl-tRNA hydrolase activity
B1H29_RS21795	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
B1H29_RS21800	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
B1H29_RS21805	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
B1H29_RS21820	COG4585	Histidine kinase
B1H29_RS21850	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B1H29_RS21860	COG2814	Major facilitator Superfamily
B1H29_RS21865	COG1136	(ABC) transporter
B1H29_RS21870	COG0577	efflux transmembrane transporter activity
B1H29_RS21915	COG4974	Belongs to the 'phage' integrase family
B1H29_RS21970	COG0148	phosphopyruvate hydratase activity
B1H29_RS21990	COG1252	NADH dehydrogenase
B1H29_RS21995	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
B1H29_RS22000	COG0577	efflux transmembrane transporter activity
B1H29_RS22005	COG1136	(ABC) transporter
B1H29_RS22045	COG0183	Belongs to the thiolase family
B1H29_RS22050	COG2755	lipolytic protein G-D-S-L family
B1H29_RS22065	COG1316	TRANSCRIPTIONal
B1H29_RS22085	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
B1H29_RS22090	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B1H29_RS22100	COG1228	amidohydrolase
B1H29_RS22110	COG1191	sigma factor activity
B1H29_RS22115	COG1366	Belongs to the anti-sigma-factor antagonist family
B1H29_RS22125	COG3104	oligopeptide transport
B1H29_RS22130	COG0745	RESPONSE REGULATOR receiver
B1H29_RS22135	COG2205	protein histidine kinase activity
B1H29_RS22190	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
B1H29_RS22205	COG1316	TRANSCRIPTIONal
B1H29_RS22210	COG1316	TRANSCRIPTIONal
B1H29_RS22220	COG1316	TRANSCRIPTIONal
B1H29_RS22225	COG1316	TRANSCRIPTIONal
B1H29_RS22230	COG1316	TRANSCRIPTIONal
B1H29_RS22235	COG1316	TRANSCRIPTIONal
B1H29_RS22240	COG1316	TRANSCRIPTIONal
B1H29_RS22265	COG0778	Nitroreductase
B1H29_RS22265	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
B1H29_RS22270	COG0391	Required for morphogenesis under gluconeogenic growth conditions
B1H29_RS22310	COG1620	l-lactate permease
B1H29_RS22315	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B1H29_RS22320	COG2835	tetraacyldisaccharide 4'-kinase activity
B1H29_RS22330	COG1482	cell wall glycoprotein biosynthetic process
B1H29_RS22340	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
B1H29_RS22385	COG0714	Associated with various cellular activities
B1H29_RS22405	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
B1H29_RS22410	COG0745	RESPONSE REGULATOR receiver
B1H29_RS22415	COG5002	protein histidine kinase activity
B1H29_RS22420	COG0823	Involved in the tonB-independent uptake of proteins
B1H29_RS22430	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
B1H29_RS22435	COG2197	response regulator
B1H29_RS22440	COG3214	Protein conserved in bacteria
B1H29_RS22450	COG0653	protein targeting
B1H29_RS22470	COG2902	Dehydrogenase
B1H29_RS22480	COG1216	Glycosyl transferase, family 2
B1H29_RS22485	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
B1H29_RS22490	COG1134	teichoic acid transport
B1H29_RS22515	COG1846	Transcriptional regulator
B1H29_RS22520	COG1764	response to oxidative stress
B1H29_RS22540	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
B1H29_RS22550	COG0395	ABC-type sugar transport system, permease component
B1H29_RS22555	COG1175	transmembrane transport
B1H29_RS22570	COG0515	serine threonine protein kinase
B1H29_RS22575	COG0515	serine threonine protein kinase
B1H29_RS22580	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
B1H29_RS22595	COG2884	Cell division ATP-binding protein ftsE
B1H29_RS22605	COG0793	Belongs to the peptidase S41A family
B1H29_RS22610	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
B1H29_RS22645	COG2223	nitrite transmembrane transporter activity
B1H29_RS22675	COG3973	AAA domain
B1H29_RS22685	COG0776	regulation of translation
B1H29_RS22690	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
B1H29_RS22695	COG1678	Uncharacterized ACR, COG1678
B1H29_RS22715	COG0395	ABC-type sugar transport system, permease component
B1H29_RS22725	COG3525	Glycosyl hydrolase, family 20, catalytic domain
B1H29_RS22740	COG1529	Aldehyde oxidase and xanthine dehydrogenase
B1H29_RS22775	COG1174	glycine betaine transport
B1H29_RS22785	COG1174	glycine betaine transport
B1H29_RS22795	COG3185	4-Hydroxyphenylpyruvate dioxygenase
B1H29_RS22805	COG0277	FAD linked oxidase domain protein
B1H29_RS22820	COG1714	RDD family
B1H29_RS22840	COG1335	isochorismatase
B1H29_RS22850	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
B1H29_RS22865	COG1113	amino acid transport
B1H29_RS22895	COG1234	tRNA 3'-trailer cleavage
B1H29_RS22900	COG1263	PTS System
B1H29_RS22905	COG1263	PTS System
B1H29_RS22910	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B1H29_RS22915	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
B1H29_RS22925	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
B1H29_RS22960	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B1H29_RS22975	COG4555	ABC transporter
B1H29_RS22990	COG2733	membrane
B1H29_RS23015	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B1H29_RS23135	COG4702	Belongs to the UPF0303 family
B1H29_RS23140	COG0673	inositol 2-dehydrogenase activity
B1H29_RS23205	COG3397	chitin binding
B1H29_RS23225	COG1126	abc transporter atp-binding protein
B1H29_RS23230	COG0765	amino acid transport
B1H29_RS23235	COG0765	amino acid transport
B1H29_RS23240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B1H29_RS23255	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B1H29_RS23300	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B1H29_RS23350	COG0406	alpha-ribazole phosphatase activity
B1H29_RS23365	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
B1H29_RS23375	COG0745	RESPONSE REGULATOR receiver
B1H29_RS23385	COG3469	chitinase activity
B1H29_RS23395	COG0395	ABC-type sugar transport system, permease component
B1H29_RS23425	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
B1H29_RS23430	COG4977	sequence-specific DNA binding
B1H29_RS23440	COG0589	response to stress
B1H29_RS23445	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
B1H29_RS23475	COG3486	L-lysine 6-monooxygenase (NADPH) activity
B1H29_RS23495	COG1960	acyl-CoA dehydrogenase activity
B1H29_RS23510	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B1H29_RS23515	COG1309	transcriptional regulator
B1H29_RS23525	COG1946	Acyl-CoA thioesterase
B1H29_RS23550	COG0028	Belongs to the TPP enzyme family
B1H29_RS23555	COG2356	endonuclease I
B1H29_RS23560	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
B1H29_RS23560	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
B1H29_RS23620	COG1472	Belongs to the glycosyl hydrolase 3 family
B1H29_RS23640	COG1609	Transcriptional regulator
B1H29_RS23645	COG0673	inositol 2-dehydrogenase activity
B1H29_RS23720	COG1869	D-ribose catabolic process
B1H29_RS23725	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B1H29_RS23730	COG1879	ABC-type sugar transport system periplasmic component
B1H29_RS23735	COG1129	ABC transporter
B1H29_RS23740	COG1609	Transcriptional regulator
B1H29_RS23750	COG1595	DNA-templated transcription, initiation
B1H29_RS23765	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
B1H29_RS23790	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B1H29_RS23865	COG0438	transferase activity, transferring glycosyl groups
B1H29_RS23875	COG0728	peptidoglycan biosynthetic process
B1H29_RS23885	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
B1H29_RS23915	COG2304	oxidoreductase activity
B1H29_RS23950	COG0629	single-stranded DNA binding
B1H29_RS23960	COG0038	chloride channel
B1H29_RS23995	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
B1H29_RS24025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B1H29_RS24040	COG1486	melibiose metabolic process
B1H29_RS24045	COG0395	ABC-type sugar transport system, permease component
B1H29_RS24055	COG0668	transmembrane transport
B1H29_RS24075	COG1136	(ABC) transporter
B1H29_RS24085	COG3525	Glycosyl hydrolase, family 20, catalytic domain
B1H29_RS24105	COG1846	Transcriptional regulator
B1H29_RS24110	COG0697	spore germination
B1H29_RS24165	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
B1H29_RS24175	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
B1H29_RS24180	COG1113	amino acid transport
B1H29_RS24185	COG1268	BioY protein
B1H29_RS24190	COG1113	amino acid transport
B1H29_RS24215	COG4552	Acetyltransferase involved in intracellular survival and related
B1H29_RS24230	COG3594	Acyltransferase
B1H29_RS24255	COG0494	nUDIX hydrolase
B1H29_RS24335	COG0544	peptidyl-prolyl cis-trans isomerase activity
B1H29_RS24340	COG0740	serine-type endopeptidase activity
B1H29_RS24345	COG0740	serine-type endopeptidase activity
B1H29_RS24350	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
B1H29_RS24360	COG0525	valine-tRNA ligase activity
B1H29_RS24365	COG0285	dihydrofolate synthase activity
B1H29_RS24375	COG0105	UTP biosynthetic process
B1H29_RS24380	COG1077	Cell shape determining protein MreB Mrl
B1H29_RS24395	COG0768	penicillin binding
B1H29_RS24400	COG0772	Belongs to the SEDS family
B1H29_RS24415	COG2226	methyltransferase
B1H29_RS24430	COG1530	ribonuclease E activity
B1H29_RS24435	COG0371	Dehydrogenase
B1H29_RS24440	COG0261	This protein binds to 23S rRNA in the presence of protein L20
B1H29_RS24445	COG0211	Belongs to the bacterial ribosomal protein bL27 family
B1H29_RS24450	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
B1H29_RS24455	COG0438	transferase activity, transferring glycosyl groups
B1H29_RS24460	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
B1H29_RS24465	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
B1H29_RS24485	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
B1H29_RS24495	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
B1H29_RS24510	COG0501	Belongs to the peptidase M48B family
B1H29_RS24525	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
B1H29_RS24535	COG0799	negative regulation of ribosome biogenesis
B1H29_RS24540	COG0588	phosphoglycerate mutase activity
B1H29_RS24560	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
B1H29_RS24570	COG0495	leucyl-tRNA aminoacylation
B1H29_RS24580	COG1307	EDD domain protein, DegV family
B1H29_RS24590	COG1555	photosystem II stabilization
B1H29_RS24625	COG2162	N-hydroxyarylamine O-acetyltransferase activity
B1H29_RS24640	COG0268	Binds directly to 16S ribosomal RNA
B1H29_RS24645	COG0481	GTPase activity
B1H29_RS24685	COG1420	regulation of RNA biosynthetic process
B1H29_RS24690	COG0484	heat shock protein binding
B1H29_RS24715	COG0793	Belongs to the peptidase S41A family
B1H29_RS24715	COG4946	Tricorn protease homolog
B1H29_RS24720	COG0537	adenosine 5'-monophosphoramidase activity
B1H29_RS24725	COG1234	tRNA 3'-trailer cleavage
B1H29_RS24730	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
B1H29_RS24740	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B1H29_RS24745	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
B1H29_RS24765	COG2315	Protein conserved in bacteria
B1H29_RS24775	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
B1H29_RS24785	COG2723	6-phospho-beta-galactosidase activity
B1H29_RS24805	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B1H29_RS24850	COG2409	Drug exporters of the RND superfamily
B1H29_RS24855	COG4585	Histidine kinase
B1H29_RS24860	COG2197	response regulator
B1H29_RS24915	COG1381	Involved in DNA repair and RecF pathway recombination
B1H29_RS24920	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
B1H29_RS24930	COG1108	ABC-type Mn2 Zn2 transport systems permease components
B1H29_RS24935	COG1121	(ABC) transporter
B1H29_RS24940	COG3443	Belongs to the bacterial solute-binding protein 9 family
B1H29_RS24940	COG0803	Belongs to the bacterial solute-binding protein 9 family
B1H29_RS24945	COG0423	glycine-tRNA ligase activity
B1H29_RS24955	COG0477	Major facilitator Superfamily
B1H29_RS24970	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
B1H29_RS24990	COG0574	Belongs to the PEP-utilizing enzyme family
B1H29_RS24990	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
B1H29_RS24995	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
B1H29_RS25005	COG4221	oxidoreductase activity
B1H29_RS25010	COG1028	Short-chain dehydrogenase reductase Sdr
B1H29_RS25025	COG2146	nitrite reductase [NAD(P)H] activity
B1H29_RS25025	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B1H29_RS25045	COG1733	regulation of RNA biosynthetic process
B1H29_RS25075	COG0243	molybdopterin cofactor binding
B1H29_RS25080	COG2949	membrane
B1H29_RS25090	COG0232	Belongs to the dGTPase family. Type 2 subfamily
B1H29_RS25100	COG0358	DNA primase activity
B1H29_RS25125	COG1070	Carbohydrate kinase
B1H29_RS25165	COG1077	Cell shape determining protein MreB Mrl
B1H29_RS25170	COG0515	serine threonine protein kinase
B1H29_RS25170	COG2815	serine threonine protein kinase
B1H29_RS25175	COG2255	four-way junction helicase activity
B1H29_RS25190	COG1404	Belongs to the peptidase S8 family
B1H29_RS25195	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
B1H29_RS25195	COG0825	malonyl-CoA metabolic process
B1H29_RS25200	COG0318	PFAM AMP-dependent synthetase and ligase
B1H29_RS25210	COG2186	Transcriptional regulator
B1H29_RS25225	COG1414	Transcriptional regulator
B1H29_RS25230	COG3386	PFAM SMP-30 Gluconolaconase
B1H29_RS25265	COG1175	transmembrane transport
B1H29_RS25270	COG0395	ABC-type sugar transport system, permease component
B1H29_RS25295	COG2267	carboxylic ester hydrolase activity
B1H29_RS25300	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
B1H29_RS25305	COG3507	Belongs to the glycosyl hydrolase 43 family
B1H29_RS25310	COG3940	Belongs to the glycosyl hydrolase 43 family
B1H29_RS25315	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
B1H29_RS25325	COG4214	carbohydrate transport
B1H29_RS25370	COG2130	NADP-dependent
B1H29_RS25375	COG1764	response to oxidative stress
B1H29_RS25405	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B1H29_RS25410	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B1H29_RS25415	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B1H29_RS25430	COG1741	Belongs to the pirin family
B1H29_RS25460	COG0789	Transcriptional regulator
B1H29_RS25465	COG0667	Aldo Keto reductase
B1H29_RS25480	COG1309	transcriptional regulator
B1H29_RS25485	COG0477	Major facilitator Superfamily
B1H29_RS25500	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
B1H29_RS25550	COG1358	cellular component organization or biogenesis
B1H29_RS25560	COG0586	Pfam SNARE associated Golgi protein
B1H29_RS25565	COG4585	Histidine kinase
B1H29_RS25675	COG4122	O-methyltransferase activity
B1H29_RS25710	COG1335	isochorismatase
B1H29_RS25725	COG3845	ABC transporter
B1H29_RS25745	COG1309	transcriptional regulator
B1H29_RS25750	COG0438	transferase activity, transferring glycosyl groups
B1H29_RS25775	COG0860	N-Acetylmuramoyl-L-alanine amidase
B1H29_RS25775	COG2247	cell wall binding repeat
B1H29_RS25785	COG0477	Major facilitator Superfamily
B1H29_RS25795	COG2197	response regulator
B1H29_RS25800	COG4585	Histidine kinase
B1H29_RS25810	COG1131	(ABC) transporter
B1H29_RS25815	COG2030	dehydratase
B1H29_RS25830	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
B1H29_RS25845	COG0800	Aldolase
B1H29_RS25850	COG3022	response to hydroperoxide
B1H29_RS25885	COG2124	cytochrome p450
B1H29_RS25895	COG0515	serine threonine protein kinase
B1H29_RS25895	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B1H29_RS25930	COG4249	Peptidase C14 caspase catalytic subunit p20
B1H29_RS25930	COG2319	Wd-40 repeat
B1H29_RS26000	COG3540	Alkaline phosphatase
B1H29_RS26010	COG2814	Major facilitator Superfamily
B1H29_RS26015	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B1H29_RS26025	COG2197	response regulator
B1H29_RS26085	COG1994	Peptidase M50
B1H29_RS26105	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
B1H29_RS26115	COG2814	Major facilitator Superfamily
B1H29_RS26140	COG0174	glutamine synthetase
B1H29_RS26155	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
B1H29_RS26155	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B1H29_RS26165	COG4115	mRNA cleavage
B1H29_RS26170	COG2161	toxin-antitoxin pair type II binding
B1H29_RS26180	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
B1H29_RS26200	COG1609	Transcriptional regulator
B1H29_RS26205	COG1653	transport
B1H29_RS26210	COG1175	transmembrane transport
B1H29_RS26215	COG3833	ABC-type maltose transport systems, permease component
B1H29_RS26220	COG0366	Alpha amylase catalytic
B1H29_RS26245	COG1309	transcriptional regulator
B1H29_RS26275	COG2197	response regulator
B1H29_RS26285	COG1090	epimerase
B1H29_RS26330	COG0174	glutamine synthetase
B1H29_RS26350	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
B1H29_RS26355	COG0321	lipoyl(octanoyl) transferase activity
B1H29_RS26380	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B1H29_RS26400	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
B1H29_RS26410	COG0508	dehydrogenase complex catalyzes the overall conversion of
B1H29_RS26415	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B1H29_RS26420	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
B1H29_RS26430	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
B1H29_RS26440	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
B1H29_RS26465	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B1H29_RS26490	COG4585	Histidine kinase
B1H29_RS26495	COG2197	response regulator
B1H29_RS26500	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B1H29_RS26505	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
B1H29_RS26525	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B1H29_RS26535	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
B1H29_RS26540	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
B1H29_RS26550	COG1376	ErfK ybiS ycfS ynhG family protein
B1H29_RS26560	COG1845	cytochrome c oxidase, subunit III
B1H29_RS26565	COG2010	Cytochrome c
B1H29_RS26570	COG0723	plastoquinol--plastocyanin reductase activity
B1H29_RS26575	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
B1H29_RS26580	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
B1H29_RS26585	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
B1H29_RS26590	COG1929	Belongs to the glycerate kinase type-1 family
B1H29_RS26600	COG0745	RESPONSE REGULATOR receiver
B1H29_RS26605	COG2205	protein histidine kinase activity
B1H29_RS26675	COG0003	Pfam Anion-transporting ATPase
B1H29_RS26685	COG1940	carbohydrate kinase activity
B1H29_RS26710	COG4585	Histidine kinase
B1H29_RS26715	COG2197	response regulator
B1H29_RS26720	COG0205	6-phosphofructokinase activity
B1H29_RS26725	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B1H29_RS26745	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
B1H29_RS26755	COG2193	ferroxidase activity
B1H29_RS26760	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
B1H29_RS26765	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
B1H29_RS26770	COG2815	serine threonine protein kinase
B1H29_RS26770	COG0515	serine threonine protein kinase
B1H29_RS26775	COG2022	thiamine diphosphate biosynthetic process
B1H29_RS26785	COG2022	thiamine diphosphate biosynthetic process
B1H29_RS26785	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B1H29_RS26805	COG0352	thiamine-phosphate diphosphorylase activity
B1H29_RS26825	COG1309	transcriptional regulator
B1H29_RS26835	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
B1H29_RS26855	COG0714	Associated with various cellular activities
B1H29_RS26865	COG0275	rRNA processing
B1H29_RS26875	COG0768	penicillin binding
B1H29_RS26880	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
B1H29_RS26890	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
B1H29_RS26895	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
B1H29_RS26905	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
B1H29_RS26910	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
B1H29_RS26920	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
B1H29_RS26925	COG1496	oxidoreductase activity
B1H29_RS26935	COG1799	cell septum assembly
B1H29_RS26945	COG3599	regulation of cell shape
B1H29_RS26950	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
B1H29_RS26965	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
B1H29_RS27015	COG0587	DNA-directed DNA polymerase activity
B1H29_RS27025	COG1432	Conserved Protein
B1H29_RS27045	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
B1H29_RS27065	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
B1H29_RS27070	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
B1H29_RS27075	COG0131	Imidazoleglycerol-phosphate dehydratase
B1H29_RS27080	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
B1H29_RS27085	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
B1H29_RS27090	COG0251	oxidation-reduction process
B1H29_RS27095	COG0107	imidazoleglycerol-phosphate synthase activity
B1H29_RS27115	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
B1H29_RS27140	COG0134	indole-3-glycerol-phosphate synthase activity
B1H29_RS27150	COG0133	tryptophan synthase activity
B1H29_RS27155	COG0159	tryptophan synthase activity
B1H29_RS27165	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
B1H29_RS27170	COG2301	Belongs to the HpcH HpaI aldolase family
B1H29_RS27175	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B1H29_RS27205	COG0070	glutamate synthase
B1H29_RS27205	COG0069	glutamate synthase activity
B1H29_RS27205	COG0067	glutamate synthase
B1H29_RS27225	COG2304	oxidoreductase activity
B1H29_RS27240	COG0287	Prephenate dehydrogenase
B1H29_RS27240	COG1605	Chorismate mutase
B1H29_RS27260	COG0737	Belongs to the 5'-nucleotidase family
B1H29_RS27315	COG2050	protein possibly involved in aromatic compounds catabolism
B1H29_RS27355	COG1643	Atp-dependent helicase
B1H29_RS27380	COG0237	dephospho-CoA kinase activity
B1H29_RS27400	COG2226	methyltransferase
B1H29_RS27420	COG2267	carboxylic ester hydrolase activity
B1H29_RS27445	COG0402	S-adenosylhomocysteine deaminase activity
B1H29_RS27495	COG0598	Magnesium transport protein CorA
B1H29_RS27500	COG2226	methyltransferase
B1H29_RS27505	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
B1H29_RS27505	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
B1H29_RS27510	COG2313	pseudouridylate synthase activity
B1H29_RS27520	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
B1H29_RS27525	COG0584	glycerophosphoryl diester phosphodiesterase
B1H29_RS27535	COG0556	nucleotide-excision repair
B1H29_RS27555	COG0387	Pfam Sodium calcium exchanger
B1H29_RS27560	COG1619	proteins homologs of microcin C7 resistance protein MccF
B1H29_RS27565	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
B1H29_RS27580	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
B1H29_RS27615	COG0322	excinuclease ABC activity
B1H29_RS27620	COG1660	Displays ATPase and GTPase activities
B1H29_RS27625	COG0391	Required for morphogenesis under gluconeogenic growth conditions
B1H29_RS27630	COG1481	regulation of sporulation
B1H29_RS27640	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
B1H29_RS27645	COG0126	phosphoglycerate kinase activity
B1H29_RS27650	COG0149	triose-phosphate isomerase activity
B1H29_RS27655	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
B1H29_RS27665	COG0166	Belongs to the GPI family
B1H29_RS27675	COG1136	(ABC) transporter
B1H29_RS27680	COG1695	Transcriptional regulator
B1H29_RS27685	COG1653	transport
B1H29_RS27690	COG0366	Alpha amylase catalytic
B1H29_RS27695	COG1653	transport
B1H29_RS27700	COG1175	transmembrane transport
B1H29_RS27705	COG0395	ABC-type sugar transport system, permease component
B1H29_RS27710	COG0363	glucosamine-6-phosphate deaminase activity
B1H29_RS27725	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
B1H29_RS27740	COG0109	protoheme IX farnesyltransferase activity
B1H29_RS27755	COG1612	heme a metabolic process
B1H29_RS27765	COG1131	(ABC) transporter
B1H29_RS27770	COG2746	aminoglycoside 3-N-acetyltransferase activity
B1H29_RS27785	COG0719	Fe-S assembly protein
B1H29_RS27795	COG0396	ATPase activity
B1H29_RS27800	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
B1H29_RS27805	COG0822	iron-sulfur transferase activity
B1H29_RS27810	COG2151	metal-sulfur cluster biosynthetic enzyme
B1H29_RS27820	COG3226	Transcriptional regulator
B1H29_RS27825	COG2171	N-acyltransferase activity
B1H29_RS27835	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B1H29_RS27880	COG1802	Transcriptional regulator
B1H29_RS27890	COG1309	transcriptional regulator
B1H29_RS27920	COG1132	(ABC) transporter
B1H29_RS27925	COG1063	alcohol dehydrogenase
B1H29_RS27945	COG1349	DNA-binding transcription factor activity
B1H29_RS27950	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B1H29_RS27955	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B1H29_RS27975	COG1802	Transcriptional regulator
B1H29_RS27995	COG0395	ABC-type sugar transport system, permease component
B1H29_RS28010	COG3507	Belongs to the glycosyl hydrolase 43 family
B1H29_RS28015	COG3866	Pectate lyase
B1H29_RS28020	COG1653	transport
B1H29_RS28025	COG2755	lipolytic protein G-D-S-L family
B1H29_RS28030	COG3866	Pectate lyase
B1H29_RS28035	COG4677	pectinesterase activity
B1H29_RS28050	COG5297	Belongs to the glycosyl hydrolase family 6
B1H29_RS28060	COG1595	DNA-templated transcription, initiation
B1H29_RS28070	COG2197	response regulator
B1H29_RS28075	COG4585	Histidine kinase
B1H29_RS28090	COG1414	Transcriptional regulator
B1H29_RS28120	COG5285	phytanoyl-CoA dioxygenase
B1H29_RS28125	COG1917	Cupin 2, conserved barrel domain protein
B1H29_RS28130	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
B1H29_RS28135	COG0456	acetyltransferase
B1H29_RS28140	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
B1H29_RS28195	COG1797	cobyrinic acid a,c-diamide synthase activity
B1H29_RS28215	COG1492	cobalamin metabolic process
B1H29_RS28220	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
B1H29_RS28235	COG0235	Class ii aldolase
B1H29_RS28260	COG0488	(ABC) transporter
B1H29_RS28270	COG1024	Enoyl-CoA hydratase
B1H29_RS28310	COG3387	PFAM Glycoside hydrolase 15-related
B1H29_RS28330	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
B1H29_RS28345	COG1404	Belongs to the peptidase S8 family
B1H29_RS28360	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B1H29_RS28365	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
B1H29_RS28385	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
B1H29_RS28400	COG1028	Short-chain dehydrogenase reductase Sdr
B1H29_RS28415	COG2186	Transcriptional regulator
B1H29_RS28420	COG2807	transmembrane transport
B1H29_RS28435	COG0588	phosphoglycerate mutase activity
B1H29_RS28440	COG3830	Belongs to the UPF0237 family
B1H29_RS28440	COG0560	Phosphoserine phosphatase
B1H29_RS28450	COG0842	Transport permease protein
B1H29_RS28450	COG1131	(ABC) transporter
B1H29_RS28450	COG1716	ATPase activity
B1H29_RS28460	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
B1H29_RS28465	COG4221	oxidoreductase activity
B1H29_RS28470	COG4585	Histidine kinase
B1H29_RS28475	COG2197	response regulator
B1H29_RS28490	COG1119	ATPase activity
B1H29_RS28510	COG1881	PFAM PEBP family protein
B1H29_RS28520	COG2094	Belongs to the DNA glycosylase MPG family
B1H29_RS28550	COG0647	UMP catabolic process
B1H29_RS28555	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B1H29_RS28560	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B1H29_RS28565	COG1120	ATPase activity
B1H29_RS28585	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
B1H29_RS28590	COG0497	DNA recombination
B1H29_RS28600	COG0438	transferase activity, transferring glycosyl groups
B1H29_RS28610	COG3387	PFAM Glycoside hydrolase 15-related
B1H29_RS28620	COG0504	CTP synthase activity
B1H29_RS28625	COG0494	nUDIX hydrolase
B1H29_RS28635	COG0686	Belongs to the AlaDH PNT family
B1H29_RS28650	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
B1H29_RS28655	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
B1H29_RS28660	COG1187	pseudouridine synthase activity
B1H29_RS28665	COG0494	nUDIX hydrolase
B1H29_RS28700	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
B1H29_RS28710	COG1160	GTP binding
B1H29_RS28745	COG0671	phosphoesterase, PA-phosphatase related
B1H29_RS28755	COG0477	Major facilitator Superfamily
B1H29_RS28760	COG1960	acyl-CoA dehydrogenase activity
B1H29_RS28765	COG1799	cell septum assembly
B1H29_RS28795	COG0587	DNA-directed DNA polymerase activity
B1H29_RS28805	COG0662	Cupin 2, conserved barrel domain protein
B1H29_RS28805	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
B1H29_RS28850	COG1725	Transcriptional regulator
B1H29_RS28880	COG2755	lipolytic protein G-D-S-L family
B1H29_RS28885	COG0515	serine threonine protein kinase
B1H29_RS28885	COG2815	serine threonine protein kinase
B1H29_RS28905	COG1595	DNA-templated transcription, initiation
B1H29_RS28930	COG2188	Transcriptional regulator
B1H29_RS28935	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
B1H29_RS28945	COG1309	transcriptional regulator
B1H29_RS28950	COG0243	molybdopterin cofactor binding
B1H29_RS28955	COG2851	Citrate transporter
B1H29_RS28965	COG3842	ATPase activity
B1H29_RS28990	COG0640	Transcriptional regulator
B1H29_RS29000	COG1960	acyl-CoA dehydrogenase activity
B1H29_RS29020	COG0789	Transcriptional regulator
B1H29_RS29045	COG3876	Protein conserved in bacteria
B1H29_RS29055	COG0318	PFAM AMP-dependent synthetase and ligase
B1H29_RS29090	COG2149	membrane
B1H29_RS29095	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
B1H29_RS29110	COG1063	alcohol dehydrogenase
B1H29_RS29115	COG1028	Short-chain dehydrogenase reductase Sdr
B1H29_RS29120	COG3265	gluconokinase activity
B1H29_RS29130	COG3012	SEC-C Motif Domain Protein
B1H29_RS29140	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B1H29_RS29170	COG0667	Aldo Keto reductase
B1H29_RS29175	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B1H29_RS29185	COG0598	Magnesium transport protein CorA
B1H29_RS29190	COG0588	phosphoglycerate mutase activity
B1H29_RS29205	COG0215	cysteine-tRNA ligase activity
B1H29_RS29215	COG2186	Transcriptional regulator
B1H29_RS29220	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
B1H29_RS29225	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
B1H29_RS29230	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
B1H29_RS29235	COG1414	Transcriptional regulator
B1H29_RS29240	COG0646	methionine synthase
B1H29_RS29240	COG1410	methionine synthase
B1H29_RS29245	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B1H29_RS29255	COG4166	transmembrane transport
B1H29_RS29260	COG2197	response regulator
B1H29_RS29270	COG1994	Peptidase M50
B1H29_RS29270	COG0517	IMP dehydrogenase activity
B1H29_RS29295	COG1222	aaa ATPase
B1H29_RS29300	COG4122	O-methyltransferase activity
B1H29_RS29315	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
B1H29_RS29320	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
B1H29_RS29325	COG1609	Transcriptional regulator
B1H29_RS29335	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
B1H29_RS29340	COG0545	Peptidyl-prolyl cis-trans isomerase
B1H29_RS29370	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B1H29_RS29375	COG0805	protein transport
B1H29_RS29410	COG0564	pseudouridine synthase activity
B1H29_RS29425	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B1H29_RS29430	COG4175	Glycine betaine
B1H29_RS29430	COG0517	IMP dehydrogenase activity
B1H29_RS29435	COG4176	ABC-type proline glycine betaine transport system permease component
B1H29_RS29460	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
B1H29_RS29470	COG0174	glutamine synthetase
B1H29_RS29475	COG1012	belongs to the aldehyde dehydrogenase family
B1H29_RS29520	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
B1H29_RS29525	COG0291	Belongs to the bacterial ribosomal protein bL35 family
B1H29_RS29530	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
B1H29_RS29535	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B1H29_RS29540	COG5002	protein histidine kinase activity
B1H29_RS29545	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
B1H29_RS29550	COG0072	phenylalanine-tRNA ligase activity
B1H29_RS29550	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B1H29_RS29575	COG1649	PFAM Uncharacterised BCR, COG1649
B1H29_RS29585	COG0697	spore germination
B1H29_RS29605	COG3751	2OG-Fe(II) oxygenase superfamily
B1H29_RS29640	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
B1H29_RS29645	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
B1H29_RS29650	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
B1H29_RS29655	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
B1H29_RS29660	COG1438	arginine binding
B1H29_RS29675	COG1017	nitric oxide dioxygenase activity
B1H29_RS29675	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B1H29_RS29690	COG0165	Argininosuccinate lyase
B1H29_RS29705	COG0477	Major facilitator Superfamily
B1H29_RS29720	COG0584	glycerophosphoryl diester phosphodiesterase
B1H29_RS29750	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
B1H29_RS29755	COG2011	ABC-type metal ion transport system permease component
B1H29_RS29760	COG1464	Belongs to the NlpA lipoprotein family
B1H29_RS29775	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
B1H29_RS29780	COG1648	precorrin-2 dehydrogenase activity
B1H29_RS29780	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
B1H29_RS29835	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
B1H29_RS29845	COG0456	acetyltransferase
B1H29_RS29890	COG1175	transmembrane transport
B1H29_RS29895	COG0395	ABC-type sugar transport system, permease component
B1H29_RS29920	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B1H29_RS29935	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
B1H29_RS29955	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
B1H29_RS29960	COG1560	Kdo2-lipid A biosynthetic process
B1H29_RS29965	COG0438	transferase activity, transferring glycosyl groups
B1H29_RS29975	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
B1H29_RS29980	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
B1H29_RS29985	COG0217	transcriptional regulatory protein
B1H29_RS29990	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
B1H29_RS29995	COG0632	four-way junction helicase activity
B1H29_RS30000	COG2255	four-way junction helicase activity
B1H29_RS30010	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B1H29_RS30015	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B1H29_RS30020	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
B1H29_RS30030	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
B1H29_RS30035	COG1196	nuclear chromosome segregation
B1H29_RS30040	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
B1H29_RS30050	COG0124	histidyl-tRNA synthetase
B1H29_RS30065	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
B1H29_RS30085	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
B1H29_RS30090	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
B1H29_RS30110	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
B1H29_RS30115	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
B1H29_RS30120	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
B1H29_RS30130	COG0006	proline dipeptidase activity
B1H29_RS30135	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
B1H29_RS30140	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
B1H29_RS30150	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
B1H29_RS30155	COG0540	Belongs to the ATCase OTCase family
B1H29_RS30160	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
B1H29_RS30170	COG0505	Belongs to the CarA family
B1H29_RS30175	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
B1H29_RS30180	COG0167	dihydroorotate dehydrogenase activity
B1H29_RS30185	COG0284	orotidine-5'-phosphate decarboxylase activity
B1H29_RS30195	COG0194	GDP metabolic process
B1H29_RS30200	COG1758	RNA polymerase activity
B1H29_RS30210	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
B1H29_RS30225	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
B1H29_RS30235	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
B1H29_RS30240	COG2390	Transcriptional regulator
B1H29_RS30255	COG2801	Transposase and inactivated derivatives
B1H29_RS30255	COG3415	Transposase
B1H29_RS30265	COG0531	amino acid
B1H29_RS30290	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B1H29_RS30315	COG2233	PERMEase
B1H29_RS30325	COG0738	Major facilitator superfamily
B1H29_RS30330	COG1940	carbohydrate kinase activity
B1H29_RS30350	COG3201	nicotinamide mononucleotide transporter
B1H29_RS30355	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
B1H29_RS30355	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
B1H29_RS30360	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
B1H29_RS30365	COG0140	phosphoribosyl-ATP diphosphatase activity
B1H29_RS30370	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
B1H29_RS30415	COG1960	acyl-CoA dehydrogenase activity
B1H29_RS30430	COG1522	sequence-specific DNA binding
B1H29_RS30440	COG1216	Glycosyl transferase, family 2
B1H29_RS30445	COG3030	protein affecting phage T7 exclusion by the F plasmid
B1H29_RS30455	COG2270	Major facilitator Superfamily
B1H29_RS30465	COG2364	Membrane
B1H29_RS30500	COG0438	transferase activity, transferring glycosyl groups
B1H29_RS30505	COG0438	transferase activity, transferring glycosyl groups
B1H29_RS30515	COG1984	allophanate hydrolase subunit 2
B1H29_RS30520	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
B1H29_RS30525	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
B1H29_RS30530	COG4336	lyase activity
B1H29_RS30535	COG2814	Major facilitator Superfamily
B1H29_RS30565	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B1H29_RS30580	COG1414	Transcriptional regulator
B1H29_RS30585	COG2146	nitrite reductase [NAD(P)H] activity
B1H29_RS30590	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B1H29_RS30605	COG2018	Roadblock/LC7 domain
B1H29_RS30620	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
B1H29_RS30625	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
B1H29_RS30630	COG3706	GGDEF domain
B1H29_RS30635	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
B1H29_RS30650	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B1H29_RS30660	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
B1H29_RS30695	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
B1H29_RS30715	COG1716	ATPase activity
B1H29_RS30735	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
B1H29_RS30745	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
B1H29_RS30745	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
B1H29_RS30800	COG0384	phenazine biosynthesis protein PhzF
B1H29_RS30845	COG0697	spore germination
B1H29_RS30900	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
B1H29_RS30915	COG2318	DinB family
B1H29_RS30935	COG0815	Transfers the fatty acyl group on membrane lipoproteins
B1H29_RS30940	COG1028	Short-chain dehydrogenase reductase Sdr
B1H29_RS30950	COG1968	undecaprenyl-diphosphatase activity
B1H29_RS30960	COG0183	Belongs to the thiolase family
B1H29_RS30975	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
B1H29_RS31010	COG0110	maltose O-acetyltransferase activity
B1H29_RS31025	COG0640	Transcriptional regulator
B1H29_RS31040	COG0714	Associated with various cellular activities
B1H29_RS31045	COG3864	Putative metallopeptidase domain
B1H29_RS31050	COG1832	CoA-binding protein
B1H29_RS31065	COG1739	Uncharacterized protein family UPF0029
B1H29_RS31070	COG0420	3'-5' exonuclease activity
B1H29_RS31075	COG0419	ATPase involved in DNA repair
B1H29_RS31080	COG1522	sequence-specific DNA binding
B1H29_RS31110	COG0626	cystathionine gamma-synthase activity
B1H29_RS31135	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B1H29_RS31175	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
B1H29_RS31175	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B1H29_RS31185	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
B1H29_RS31190	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
B1H29_RS31225	COG1595	DNA-templated transcription, initiation
B1H29_RS31230	COG2188	Transcriptional regulator
B1H29_RS31235	COG1940	carbohydrate kinase activity
B1H29_RS31265	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
B1H29_RS31285	COG0456	acetyltransferase
B1H29_RS31300	COG2226	methyltransferase
B1H29_RS31305	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
B1H29_RS31310	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B1H29_RS31315	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
B1H29_RS31355	COG1309	transcriptional regulator
B1H29_RS31365	COG0829	nickel cation binding
B1H29_RS31385	COG0477	Major facilitator Superfamily
B1H29_RS31395	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
B1H29_RS31400	COG1834	amidinotransferase
B1H29_RS31405	COG1522	sequence-specific DNA binding
B1H29_RS31410	COG3279	Response regulator of the LytR AlgR family
B1H29_RS31420	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B1H29_RS31425	COG3275	phosphorelay sensor kinase activity
B1H29_RS31430	COG2815	serine threonine protein kinase
B1H29_RS31430	COG0515	serine threonine protein kinase
B1H29_RS31440	COG0205	6-phosphofructokinase activity
B1H29_RS31445	COG3442	glutamine amidotransferase
B1H29_RS31450	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
B1H29_RS31455	COG0242	peptide deformylase activity
B1H29_RS31465	COG1960	acyl-CoA dehydrogenase activity
B1H29_RS31480	COG1012	belongs to the aldehyde dehydrogenase family
B1H29_RS31490	COG1793	dna ligase
B1H29_RS31510	COG1960	acyl-CoA dehydrogenase activity
B1H29_RS31515	COG1960	acyl-CoA dehydrogenase activity
B1H29_RS31860	COG5002	protein histidine kinase activity
B1H29_RS31860	COG2176	DNA-directed DNA polymerase activity
B1H29_RS31940	COG0477	Major facilitator Superfamily
B1H29_RS32005	COG1012	belongs to the aldehyde dehydrogenase family
B1H29_RS32020	COG1940	carbohydrate kinase activity
B1H29_RS32020	COG1846	Transcriptional regulator
B1H29_RS32030	COG1070	Carbohydrate kinase
B1H29_RS32035	COG2115	Belongs to the xylose isomerase family
B1H29_RS32045	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
B1H29_RS32095	COG2018	Roadblock/LC7 domain
B1H29_RS32105	COG1946	Acyl-CoA thioesterase
B1H29_RS32120	COG0254	rRNA binding
B1H29_RS32130	COG1132	(ABC) transporter
B1H29_RS32150	COG1132	(ABC) transporter
B1H29_RS32160	COG2072	flavoprotein involved in K transport
B1H29_RS32165	COG0432	Pfam Uncharacterised protein family UPF0047
B1H29_RS32185	COG3290	protein histidine kinase activity
B1H29_RS32190	COG4565	transcriptional regulatory protein
B1H29_RS32200	COG2080	2 iron, 2 sulfur cluster binding
B1H29_RS32205	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
B1H29_RS32210	COG1529	Aldehyde oxidase and xanthine dehydrogenase
B1H29_RS32220	COG3387	PFAM Glycoside hydrolase 15-related
B1H29_RS32225	COG0726	polysaccharide deacetylase
B1H29_RS32235	COG4221	oxidoreductase activity
B1H29_RS32275	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B1H29_RS32305	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
B1H29_RS32315	COG1960	acyl-CoA dehydrogenase activity
B1H29_RS32330	COG1902	pentaerythritol trinitrate reductase activity
B1H29_RS32335	COG0640	Transcriptional regulator
B1H29_RS32340	COG0493	'glutamate synthase
B1H29_RS32395	COG0671	phosphoesterase, PA-phosphatase related
B1H29_RS32435	COG0584	glycerophosphoryl diester phosphodiesterase
B1H29_RS32460	COG0204	Acyl-transferase
B1H29_RS32480	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
B1H29_RS32510	COG1660	Displays ATPase and GTPase activities
B1H29_RS32515	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B1H29_RS32525	COG0445	tRNA wobble uridine modification
B1H29_RS32540	COG4585	Histidine kinase
B1H29_RS32545	COG2197	response regulator
B1H29_RS32570	COG2723	6-phospho-beta-galactosidase activity
B1H29_RS32575	COG0395	ABC-type sugar transport system, permease component
B1H29_RS32580	COG1175	transmembrane transport
B1H29_RS32590	COG1501	Belongs to the glycosyl hydrolase 31 family
B1H29_RS32605	COG0783	Belongs to the Dps family
B1H29_RS32635	COG2608	mercury ion transmembrane transporter activity
B1H29_RS32650	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
B1H29_RS32655	COG0191	fructose-bisphosphate aldolase activity
B1H29_RS32660	COG2813	Specifically methylates the guanine in position
B1H29_RS32670	COG1940	carbohydrate kinase activity
B1H29_RS32715	COG1349	DNA-binding transcription factor activity
B1H29_RS32750	COG1215	transferase activity, transferring glycosyl groups
B1H29_RS32755	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
B1H29_RS32780	COG1028	Short-chain dehydrogenase reductase Sdr
B1H29_RS32820	COG3345	alpha-galactosidase
B1H29_RS32830	COG2409	Drug exporters of the RND superfamily
B1H29_RS32835	COG4585	Histidine kinase
B1H29_RS32840	COG2197	response regulator
B1H29_RS32865	COG2610	gluconate transmembrane transporter activity
B1H29_RS32870	COG2186	Transcriptional regulator
B1H29_RS32880	COG2045	Belongs to the ComB family
B1H29_RS32900	COG1609	Transcriptional regulator
B1H29_RS32905	COG1653	transport
B1H29_RS32910	COG1175	transmembrane transport
B1H29_RS32920	COG1472	Belongs to the glycosyl hydrolase 3 family
B1H29_RS32935	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
B1H29_RS32945	COG0137	argininosuccinate synthase activity
B1H29_RS32970	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
B1H29_RS33005	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
B1H29_RS33010	COG1993	acr, cog1993
B1H29_RS33015	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
B1H29_RS33020	COG1968	undecaprenyl-diphosphatase activity
B1H29_RS33030	COG2186	Transcriptional regulator
B1H29_RS33045	COG2066	Belongs to the glutaminase family
B1H29_RS33050	COG1686	Belongs to the peptidase S11 family
B1H29_RS33055	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
B1H29_RS33065	COG1695	Transcriptional regulator
B1H29_RS33070	COG2226	methyltransferase
B1H29_RS33075	COG2188	Transcriptional regulator
B1H29_RS33080	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B1H29_RS33085	COG3458	cephalosporin-C deacetylase activity
B1H29_RS33100	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
B1H29_RS33115	COG2890	protein-(glutamine-N5) methyltransferase activity
B1H29_RS33135	COG0446	pyridine nucleotide-disulphide oxidoreductase
B1H29_RS33135	COG1902	pentaerythritol trinitrate reductase activity
B1H29_RS33170	COG1461	Dihydroxyacetone kinase
B1H29_RS33175	COG2376	Dihydroxyacetone kinase
B1H29_RS33205	COG0789	Transcriptional regulator
B1H29_RS33210	COG0659	secondary active sulfate transmembrane transporter activity
B1H29_RS33245	COG1250	3-hydroxyacyl-CoA dehydrogenase
B1H29_RS33250	COG3246	L-lysine catabolic process to acetate
B1H29_RS33290	COG2207	Transcriptional regulator
B1H29_RS33290	COG3708	Transcriptional regulator
B1H29_RS33300	COG0745	RESPONSE REGULATOR receiver
B1H29_RS33305	COG2205	protein histidine kinase activity
B1H29_RS33320	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
B1H29_RS33330	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
B1H29_RS33360	COG0515	serine threonine protein kinase
B1H29_RS33375	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B1H29_RS33385	COG0318	PFAM AMP-dependent synthetase and ligase
B1H29_RS33435	COG0673	inositol 2-dehydrogenase activity
B1H29_RS33480	COG1012	belongs to the aldehyde dehydrogenase family
B1H29_RS33485	COG0789	Transcriptional regulator
B1H29_RS33510	COG0346	lactoylglutathione lyase activity
B1H29_RS33515	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
B1H29_RS33525	COG0583	DNA-binding transcription factor activity
B1H29_RS33530	COG0667	Aldo Keto reductase
B1H29_RS33565	COG1191	sigma factor activity
B1H29_RS33575	COG0740	serine-type endopeptidase activity
B1H29_RS33580	COG0740	serine-type endopeptidase activity
B1H29_RS33585	COG0596	Alpha beta hydrolase
B1H29_RS33600	COG0328	RNA-DNA hybrid ribonuclease activity
B1H29_RS33605	COG0667	Aldo Keto reductase
B1H29_RS33625	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B1H29_RS33630	COG0515	serine threonine protein kinase
B1H29_RS33630	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B1H29_RS33635	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
B1H29_RS33645	COG2340	Cysteine-rich secretory protein family
B1H29_RS33650	COG2197	response regulator
B1H29_RS33780	COG2172	sigma factor antagonist activity
B1H29_RS33785	COG1366	Belongs to the anti-sigma-factor antagonist family
B1H29_RS33790	COG1366	Belongs to the anti-sigma-factor antagonist family
B1H29_RS33805	COG5002	protein histidine kinase activity
B1H29_RS33805	COG2205	protein histidine kinase activity
B1H29_RS33805	COG0784	Response regulator, receiver
B1H29_RS33815	COG2172	sigma factor antagonist activity
B1H29_RS33835	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
B1H29_RS33840	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
B1H29_RS33855	COG0366	Alpha amylase catalytic
B1H29_RS33895	COG0181	hydroxymethylbilane synthase activity
B1H29_RS33905	COG3285	dna ligase
B1H29_RS33905	COG1793	dna ligase
B1H29_RS33930	COG4974	Belongs to the 'phage' integrase family
B1H29_RS33935	COG2207	Transcriptional regulator
B1H29_RS33985	COG0656	L-ascorbic acid biosynthetic process
B1H29_RS34000	COG0009	L-threonylcarbamoyladenylate synthase
B1H29_RS34010	COG2124	cytochrome p450
B1H29_RS34020	COG1028	Short-chain dehydrogenase reductase Sdr
B1H29_RS34035	COG0753	catalase activity
B1H29_RS34065	COG1088	dTDP-glucose 4,6-dehydratase activity
B1H29_RS34085	COG0243	molybdopterin cofactor binding
B1H29_RS34090	COG0456	acetyltransferase
B1H29_RS34115	COG2208	phosphoserine phosphatase activity
B1H29_RS34115	COG2770	Histidine kinase
B1H29_RS34135	COG0142	geranyltranstransferase activity
B1H29_RS34165	COG1028	Short-chain dehydrogenase reductase Sdr
B1H29_RS34170	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
B1H29_RS34175	COG2226	methyltransferase
B1H29_RS34230	COG1120	ATPase activity
B1H29_RS34255	COG0110	maltose O-acetyltransferase activity
B1H29_RS34275	COG0395	ABC-type sugar transport system, permease component
B1H29_RS34280	COG4209	transmembrane transport
B1H29_RS34295	COG0028	Belongs to the TPP enzyme family
B1H29_RS34300	COG1028	Short-chain dehydrogenase reductase Sdr
B1H29_RS34325	COG1063	alcohol dehydrogenase
B1H29_RS34355	COG2197	response regulator
B1H29_RS34380	COG1959	2 iron, 2 sulfur cluster binding
B1H29_RS34385	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B1H29_RS34385	COG1017	nitric oxide dioxygenase activity
B1H29_RS34405	COG5640	endopeptidase activity
B1H29_RS34410	COG0583	DNA-binding transcription factor activity
B1H29_RS34420	COG2814	Major facilitator Superfamily
B1H29_RS34435	COG0583	DNA-binding transcription factor activity
B1H29_RS34445	COG3340	Belongs to the peptidase S51 family
B1H29_RS34485	COG2267	carboxylic ester hydrolase activity
B1H29_RS34530	COG1335	isochorismatase
B1H29_RS34560	COG1119	ATPase activity
B1H29_RS34565	COG5640	endopeptidase activity
B1H29_RS34595	COG2124	cytochrome p450
B1H29_RS34615	COG2050	protein possibly involved in aromatic compounds catabolism
B1H29_RS34620	COG3396	Phenylacetate-CoA oxygenase
B1H29_RS34625	COG3460	Phenylacetate-CoA oxygenase
B1H29_RS34630	COG3396	Phenylacetate-CoA oxygenase
B1H29_RS34635	COG2151	metal-sulfur cluster biosynthetic enzyme
B1H29_RS34640	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B1H29_RS34670	COG1733	regulation of RNA biosynthetic process
B1H29_RS34680	COG1028	Short-chain dehydrogenase reductase Sdr
B1H29_RS34695	COG4941	Belongs to the sigma-70 factor family
B1H29_RS34700	COG3795	YCII-related domain
B1H29_RS34720	COG1953	Uracil, thiamine, allantoin
B1H29_RS34725	COG1609	Transcriptional regulator
B1H29_RS34735	COG1175	transmembrane transport
B1H29_RS34740	COG0395	ABC-type sugar transport system, permease component
B1H29_RS34760	COG0604	alcohol dehydrogenase
B1H29_RS34760	COG3321	synthase
B1H29_RS34765	COG3321	synthase
B1H29_RS34765	COG0604	alcohol dehydrogenase
B1H29_RS34780	COG3321	synthase
B1H29_RS34780	COG0604	alcohol dehydrogenase
B1H29_RS34790	COG0604	alcohol dehydrogenase
B1H29_RS34790	COG3321	synthase
B1H29_RS34805	COG3321	synthase
B1H29_RS34805	COG0604	alcohol dehydrogenase
B1H29_RS34820	COG0604	alcohol dehydrogenase
B1H29_RS34820	COG3321	synthase
B1H29_RS34845	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
B1H29_RS34880	COG2175	clavaminate synthase activity
B1H29_RS34925	COG4977	sequence-specific DNA binding
B1H29_RS34930	COG2755	lipolytic protein G-D-S-L family
B1H29_RS34935	COG0326	Molecular chaperone. Has ATPase activity
B1H29_RS34945	COG3226	Transcriptional regulator
B1H29_RS34960	COG0110	maltose O-acetyltransferase activity
B1H29_RS34980	COG1028	Short-chain dehydrogenase reductase Sdr
B1H29_RS34985	COG4948	Mandelate Racemase Muconate Lactonizing
B1H29_RS34990	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
B1H29_RS35020	COG2409	Drug exporters of the RND superfamily
B1H29_RS35025	COG0702	epimerase
B1H29_RS35030	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
B1H29_RS35045	COG0517	IMP dehydrogenase activity
B1H29_RS35055	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
B1H29_RS35065	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B1H29_RS35075	COG4948	Mandelate Racemase Muconate Lactonizing
B1H29_RS35080	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B1H29_RS35085	COG0747	negative chemotaxis
B1H29_RS35090	COG0601	transmembrane transport
B1H29_RS35095	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B1H29_RS35100	COG0444	Belongs to the ABC transporter superfamily
B1H29_RS35105	COG4608	Belongs to the ABC transporter superfamily
B1H29_RS35120	COG0584	glycerophosphoryl diester phosphodiesterase
B1H29_RS35145	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B1H29_RS35150	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
B1H29_RS35170	COG1012	belongs to the aldehyde dehydrogenase family
B1H29_RS35195	COG0395	ABC-type sugar transport system, permease component
B1H29_RS35230	COG0584	glycerophosphoryl diester phosphodiesterase
B1H29_RS35240	COG3415	Transposase
B1H29_RS35240	COG2801	Transposase and inactivated derivatives
B1H29_RS35250	COG1028	Short-chain dehydrogenase reductase Sdr
B1H29_RS35310	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
B1H29_RS35315	COG0640	Transcriptional regulator
B1H29_RS35320	COG0346	lactoylglutathione lyase activity
B1H29_RS35340	COG2197	response regulator
B1H29_RS35345	COG1132	(ABC) transporter
B1H29_RS35350	COG1132	(ABC) transporter
B1H29_RS35360	COG0515	serine threonine protein kinase
B1H29_RS35370	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
B1H29_RS35375	COG1028	Short-chain dehydrogenase reductase Sdr
B1H29_RS35390	COG1609	Transcriptional regulator
B1H29_RS35395	COG3254	rhamnose metabolic process
B1H29_RS35410	COG1172	Belongs to the binding-protein-dependent transport system permease family
B1H29_RS35415	COG1129	ABC transporter
B1H29_RS35425	COG1028	Short-chain dehydrogenase reductase Sdr
B1H29_RS35425	COG3347	Dehydrogenase
B1H29_RS35430	COG1070	Carbohydrate kinase
B1H29_RS35435	COG0247	lactate metabolic process
B1H29_RS35440	COG1139	Iron-sulfur cluster binding protein
B1H29_RS35445	COG1556	Lactate utilization protein
B1H29_RS35450	COG0523	cobalamin synthesis protein
B1H29_RS35460	COG1120	ATPase activity
B1H29_RS35465	COG1984	allophanate hydrolase subunit 2
B1H29_RS35470	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
B1H29_RS35475	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
B1H29_RS35490	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
B1H29_RS35500	COG0488	(ABC) transporter
B1H29_RS35545	COG1132	(ABC) transporter
B1H29_RS35560	COG4977	sequence-specific DNA binding
B1H29_RS35620	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B1H29_RS35625	COG2272	Belongs to the type-B carboxylesterase lipase family
B1H29_RS35660	COG2072	flavoprotein involved in K transport
B1H29_RS35670	COG3384	dioxygenase
B1H29_RS35705	COG0667	Aldo Keto reductase
B1H29_RS35765	COG0235	Class ii aldolase
B1H29_RS35770	COG3395	kinase activity
B1H29_RS35775	COG0473	3-isopropylmalate dehydrogenase activity
B1H29_RS35780	COG1082	Xylose isomerase domain protein TIM barrel
B1H29_RS35795	COG2851	Citrate transporter
B1H29_RS35815	COG2124	cytochrome p450
B1H29_RS35820	COG2197	response regulator
B1H29_RS35840	COG2205	protein histidine kinase activity
B1H29_RS35905	COG0395	ABC-type sugar transport system, permease component
B1H29_RS35910	COG1175	transmembrane transport
B1H29_RS35915	COG1653	transport
B1H29_RS35945	COG1063	alcohol dehydrogenase
B1H29_RS35950	COG0477	Major facilitator Superfamily
B1H29_RS35955	COG0246	Mannitol dehydrogenase
B1H29_RS35970	COG4221	oxidoreductase activity
B1H29_RS35990	COG1132	(ABC) transporter
B1H29_RS35995	COG4221	oxidoreductase activity
B1H29_RS36005	COG3321	synthase
B1H29_RS36005	COG1028	Short-chain dehydrogenase reductase Sdr
B1H29_RS36005	COG0604	alcohol dehydrogenase
B1H29_RS36020	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B1H29_RS36065	COG0702	epimerase
B1H29_RS36090	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B1H29_RS36130	COG2867	negative regulation of translational initiation
B1H29_RS36210	COG0154	amidase activity
B1H29_RS36220	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
B1H29_RS36230	COG0745	RESPONSE REGULATOR receiver
B1H29_RS36255	COG4977	sequence-specific DNA binding
B1H29_RS36270	COG1131	(ABC) transporter
B1H29_RS36275	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
B1H29_RS36310	COG1262	PFAM Formylglycine-generating sulfatase enzyme
B1H29_RS36320	COG1262	PFAM Formylglycine-generating sulfatase enzyme
B1H29_RS36340	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
B1H29_RS36350	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B1H29_RS36365	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
B1H29_RS36375	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B1H29_RS36395	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
B1H29_RS36405	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
B1H29_RS36420	COG1132	(ABC) transporter
B1H29_RS36435	COG1116	anion transmembrane transporter activity
B1H29_RS36455	COG0529	Catalyzes the synthesis of activated sulfate
B1H29_RS36470	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
B1H29_RS36480	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B1H29_RS36515	COG0604	alcohol dehydrogenase
B1H29_RS36520	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B1H29_RS36525	COG2124	cytochrome p450
B1H29_RS36535	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
B1H29_RS36540	COG2814	Major facilitator Superfamily
B1H29_RS36560	COG0477	Major facilitator Superfamily
B1H29_RS36570	COG3629	intracellular signal transduction
B1H29_RS36575	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
B1H29_RS36580	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B1H29_RS36720	COG1857	crispr-associated protein
B1H29_RS36720	COG1857	crispr-associated protein
B1H29_RS36935	COG0420	3'-5' exonuclease activity
B1H29_RS36940	COG0419	ATPase involved in DNA repair
B1H29_RS36955	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP