locus-tag	class	description
BC342_RS00040	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BC342_RS00085	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BC342_RS00095	COG1309	transcriptional regulator
BC342_RS00125	COG0165	Argininosuccinate lyase
BC342_RS00155	COG1024	Enoyl-CoA hydratase
BC342_RS00165	COG2175	clavaminate synthase activity
BC342_RS00180	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BC342_RS00195	COG3321	synthase
BC342_RS00195	COG0604	alcohol dehydrogenase
BC342_RS00195	COG0604	alcohol dehydrogenase
BC342_RS00195	COG3321	synthase
BC342_RS00230	COG5640	endopeptidase activity
BC342_RS00235	COG4257	antibiotic catabolic process
BC342_RS00255	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BC342_RS00260	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BC342_RS00290	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BC342_RS00295	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BC342_RS00310	COG4989	oxidoreductase activity
BC342_RS00315	COG0667	Aldo Keto reductase
BC342_RS00320	COG3250	beta-galactosidase activity
BC342_RS00330	COG1172	Belongs to the binding-protein-dependent transport system permease family
BC342_RS00335	COG1172	Belongs to the binding-protein-dependent transport system permease family
BC342_RS00340	COG1129	ABC transporter
BC342_RS00350	COG1609	Transcriptional regulator
BC342_RS00355	COG2272	Belongs to the type-B carboxylesterase lipase family
BC342_RS00390	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BC342_RS00400	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BC342_RS00425	COG0406	alpha-ribazole phosphatase activity
BC342_RS00430	COG4948	Mandelate Racemase Muconate Lactonizing
BC342_RS00455	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BC342_RS00475	COG0477	Major facilitator Superfamily
BC342_RS00500	COG0367	asparagine synthase
BC342_RS00515	COG2353	YceI-like domain
BC342_RS00530	COG1120	ATPase activity
BC342_RS00535	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BC342_RS00540	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BC342_RS00560	COG0583	DNA-binding transcription factor activity
BC342_RS00565	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BC342_RS00615	COG0477	Major facilitator Superfamily
BC342_RS00620	COG1028	Short-chain dehydrogenase reductase Sdr
BC342_RS00660	COG1028	Short-chain dehydrogenase reductase Sdr
BC342_RS00665	COG1309	transcriptional regulator
BC342_RS00670	COG1278	Cold shock
BC342_RS00685	COG1028	Short-chain dehydrogenase reductase Sdr
BC342_RS00715	COG0739	heme binding
BC342_RS00720	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
BC342_RS00745	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BC342_RS00755	COG1309	transcriptional regulator
BC342_RS00815	COG1737	Transcriptional regulator
BC342_RS00820	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BC342_RS00825	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BC342_RS00830	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BC342_RS00835	COG1349	DNA-binding transcription factor activity
BC342_RS00850	COG3395	kinase activity
BC342_RS00855	COG0235	Class ii aldolase
BC342_RS00915	COG0765	amino acid transport
BC342_RS00935	COG1028	Short-chain dehydrogenase reductase Sdr
BC342_RS00975	COG0601	transmembrane transport
BC342_RS00980	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BC342_RS00985	COG0444	Belongs to the ABC transporter superfamily
BC342_RS00995	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BC342_RS01010	COG0431	NADPH-dependent FMN reductase
BC342_RS01040	COG0714	Associated with various cellular activities
BC342_RS01045	COG2425	protein containing a von Willebrand factor type A (vWA) domain
BC342_RS01075	COG0494	nUDIX hydrolase
BC342_RS01095	COG0583	DNA-binding transcription factor activity
BC342_RS01125	COG4608	Belongs to the ABC transporter superfamily
BC342_RS01130	COG0444	Belongs to the ABC transporter superfamily
BC342_RS01135	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BC342_RS01140	COG0601	transmembrane transport
BC342_RS01145	COG0747	negative chemotaxis
BC342_RS01150	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BC342_RS01155	COG4948	Mandelate Racemase Muconate Lactonizing
BC342_RS01160	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BC342_RS01165	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BC342_RS01170	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BC342_RS01175	COG3119	arylsulfatase activity
BC342_RS01210	COG2239	Acts as a magnesium transporter
BC342_RS01225	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BC342_RS01230	COG2409	Drug exporters of the RND superfamily
BC342_RS01240	COG2205	protein histidine kinase activity
BC342_RS01245	COG0745	RESPONSE REGULATOR receiver
BC342_RS01275	COG3226	Transcriptional regulator
BC342_RS01280	COG2391	methyltransferase activity
BC342_RS01290	COG0326	Molecular chaperone. Has ATPase activity
BC342_RS01300	COG2205	protein histidine kinase activity
BC342_RS01330	COG4977	sequence-specific DNA binding
BC342_RS01350	COG2175	clavaminate synthase activity
BC342_RS01360	COG0395	ABC-type sugar transport system, permease component
BC342_RS01365	COG1175	transmembrane transport
BC342_RS01375	COG1609	Transcriptional regulator
BC342_RS01380	COG3940	Belongs to the glycosyl hydrolase 43 family
BC342_RS01385	COG1953	Uracil, thiamine, allantoin
BC342_RS01440	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BC342_RS01445	COG2151	metal-sulfur cluster biosynthetic enzyme
BC342_RS01450	COG3396	Phenylacetate-CoA oxygenase
BC342_RS01455	COG3460	Phenylacetate-CoA oxygenase
BC342_RS01460	COG3396	Phenylacetate-CoA oxygenase
BC342_RS01520	COG1119	ATPase activity
BC342_RS01540	COG2188	Transcriptional regulator
BC342_RS01550	COG1335	isochorismatase
BC342_RS01605	COG0583	DNA-binding transcription factor activity
BC342_RS01620	COG2814	Major facilitator Superfamily
BC342_RS01630	COG0583	DNA-binding transcription factor activity
BC342_RS01635	COG5640	endopeptidase activity
BC342_RS01650	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BC342_RS01650	COG1017	nitric oxide dioxygenase activity
BC342_RS01655	COG1959	2 iron, 2 sulfur cluster binding
BC342_RS01665	COG1136	(ABC) transporter
BC342_RS01665	COG0577	efflux transmembrane transporter activity
BC342_RS01675	COG4585	Histidine kinase
BC342_RS01680	COG2197	response regulator
BC342_RS01685	COG2814	Major facilitator Superfamily
BC342_RS01715	COG0028	Belongs to the TPP enzyme family
BC342_RS01720	COG1609	Transcriptional regulator
BC342_RS01725	COG4209	transmembrane transport
BC342_RS01730	COG0395	ABC-type sugar transport system, permease component
BC342_RS01760	COG4607	ABC-type enterochelin transport system periplasmic component
BC342_RS01765	COG1120	ATPase activity
BC342_RS01770	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BC342_RS01775	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BC342_RS01785	COG1120	ATPase activity
BC342_RS01800	COG1073	alpha beta
BC342_RS01840	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
BC342_RS01875	COG0475	glutathione-regulated potassium exporter activity
BC342_RS01880	COG0142	geranyltranstransferase activity
BC342_RS01920	COG0243	molybdopterin cofactor binding
BC342_RS01935	COG1088	dTDP-glucose 4,6-dehydratase activity
BC342_RS01960	COG0753	catalase activity
BC342_RS01980	COG0009	L-threonylcarbamoyladenylate synthase
BC342_RS02000	COG0656	L-ascorbic acid biosynthetic process
BC342_RS02025	COG2382	esterase
BC342_RS02050	COG3285	dna ligase
BC342_RS02050	COG1793	dna ligase
BC342_RS02060	COG0181	hydroxymethylbilane synthase activity
BC342_RS02070	COG1191	sigma factor activity
BC342_RS02105	COG0366	Alpha amylase catalytic
BC342_RS02115	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BC342_RS02120	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
BC342_RS02120	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
BC342_RS02150	COG5002	protein histidine kinase activity
BC342_RS02150	COG0784	Response regulator, receiver
BC342_RS02150	COG2205	protein histidine kinase activity
BC342_RS02165	COG1366	Belongs to the anti-sigma-factor antagonist family
BC342_RS02170	COG1366	Belongs to the anti-sigma-factor antagonist family
BC342_RS02175	COG2172	sigma factor antagonist activity
BC342_RS02190	COG1252	NADH dehydrogenase
BC342_RS02230	COG1982	Orn Lys Arg decarboxylase major
BC342_RS02240	COG0477	Major facilitator Superfamily
BC342_RS02260	COG3189	MarR family transcriptional regulator
BC342_RS02280	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BC342_RS02310	COG2197	response regulator
BC342_RS02315	COG2340	Cysteine-rich secretory protein family
BC342_RS02325	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BC342_RS02330	COG0515	serine threonine protein kinase
BC342_RS02330	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BC342_RS02335	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BC342_RS02355	COG0667	Aldo Keto reductase
BC342_RS02365	COG0328	RNA-DNA hybrid ribonuclease activity
BC342_RS02375	COG0740	serine-type endopeptidase activity
BC342_RS02380	COG0740	serine-type endopeptidase activity
BC342_RS02390	COG1191	sigma factor activity
BC342_RS02420	COG0667	Aldo Keto reductase
BC342_RS02425	COG0583	DNA-binding transcription factor activity
BC342_RS02435	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BC342_RS02440	COG0346	lactoylglutathione lyase activity
BC342_RS02470	COG0673	inositol 2-dehydrogenase activity
BC342_RS02510	COG0318	PFAM AMP-dependent synthetase and ligase
BC342_RS02515	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BC342_RS02640	COG1940	carbohydrate kinase activity
BC342_RS02650	COG1175	transmembrane transport
BC342_RS02655	COG0395	ABC-type sugar transport system, permease component
BC342_RS02670	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BC342_RS02675	COG1124	(ABC) transporter
BC342_RS02685	COG0601	transmembrane transport
BC342_RS02700	COG0667	Aldo Keto reductase
BC342_RS02705	COG0738	Major facilitator superfamily
BC342_RS02710	COG2223	nitrite transmembrane transporter activity
BC342_RS02725	COG1216	Glycosyl transferase, family 2
BC342_RS02745	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BC342_RS02750	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BC342_RS02765	COG2376	Dihydroxyacetone kinase
BC342_RS02770	COG1461	Dihydroxyacetone kinase
BC342_RS02800	COG1902	pentaerythritol trinitrate reductase activity
BC342_RS02800	COG0446	pyridine nucleotide-disulphide oxidoreductase
BC342_RS02835	COG3458	cephalosporin-C deacetylase activity
BC342_RS02840	COG2188	Transcriptional regulator
BC342_RS02845	COG2226	methyltransferase
BC342_RS02860	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BC342_RS02875	COG1968	undecaprenyl-diphosphatase activity
BC342_RS02880	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BC342_RS02885	COG1993	acr, cog1993
BC342_RS02890	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BC342_RS02895	COG1846	Transcriptional regulator
BC342_RS02915	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
BC342_RS02925	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BC342_RS02935	COG3458	cephalosporin-C deacetylase activity
BC342_RS02945	COG0747	negative chemotaxis
BC342_RS02975	COG0137	argininosuccinate synthase activity
BC342_RS02985	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BC342_RS02995	COG1472	Belongs to the glycosyl hydrolase 3 family
BC342_RS03005	COG1175	transmembrane transport
BC342_RS03010	COG1653	transport
BC342_RS03015	COG1609	Transcriptional regulator
BC342_RS03035	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BC342_RS03075	COG1349	DNA-binding transcription factor activity
BC342_RS03110	COG1940	carbohydrate kinase activity
BC342_RS03120	COG2813	Specifically methylates the guanine in position
BC342_RS03125	COG0191	fructose-bisphosphate aldolase activity
BC342_RS03145	COG0783	Belongs to the Dps family
BC342_RS03160	COG1501	Belongs to the glycosyl hydrolase 31 family
BC342_RS03170	COG1175	transmembrane transport
BC342_RS03175	COG0395	ABC-type sugar transport system, permease component
BC342_RS03180	COG2723	6-phospho-beta-galactosidase activity
BC342_RS03195	COG2197	response regulator
BC342_RS03200	COG4585	Histidine kinase
BC342_RS03205	COG0445	tRNA wobble uridine modification
BC342_RS03215	COG1660	Displays ATPase and GTPase activities
BC342_RS03245	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BC342_RS03285	COG0584	glycerophosphoryl diester phosphodiesterase
BC342_RS03315	COG1028	Short-chain dehydrogenase reductase Sdr
BC342_RS03325	COG1053	succinate dehydrogenase
BC342_RS03375	COG0671	phosphoesterase, PA-phosphatase related
BC342_RS03410	COG1960	acyl-CoA dehydrogenase activity
BC342_RS03425	COG0601	transmembrane transport
BC342_RS03445	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BC342_RS03450	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BC342_RS03455	COG2971	BadF BadG BcrA BcrD
BC342_RS03480	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BC342_RS03510	COG4221	oxidoreductase activity
BC342_RS03520	COG0726	polysaccharide deacetylase
BC342_RS03535	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BC342_RS03540	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BC342_RS03545	COG2080	2 iron, 2 sulfur cluster binding
BC342_RS03555	COG4565	transcriptional regulatory protein
BC342_RS03560	COG3290	protein histidine kinase activity
BC342_RS03585	COG0432	Pfam Uncharacterised protein family UPF0047
BC342_RS03590	COG2072	flavoprotein involved in K transport
BC342_RS03600	COG1132	(ABC) transporter
BC342_RS03615	COG1132	(ABC) transporter
BC342_RS03620	COG1132	(ABC) transporter
BC342_RS03630	COG0254	rRNA binding
BC342_RS03645	COG1946	Acyl-CoA thioesterase
BC342_RS03655	COG2018	Roadblock/LC7 domain
BC342_RS03705	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BC342_RS03715	COG2115	Belongs to the xylose isomerase family
BC342_RS03785	COG1522	sequence-specific DNA binding
BC342_RS03810	COG1609	Transcriptional regulator
BC342_RS03820	COG1175	transmembrane transport
BC342_RS03830	COG1472	Belongs to the glycosyl hydrolase 3 family
BC342_RS03835	COG0129	dihydroxy-acid dehydratase activity
BC342_RS03850	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BC342_RS03880	COG0477	Major facilitator Superfamily
BC342_RS03905	COG1960	acyl-CoA dehydrogenase activity
BC342_RS03910	COG1960	acyl-CoA dehydrogenase activity
BC342_RS03920	COG3800	Transcriptional regulator
BC342_RS03920	COG1396	sequence-specific DNA binding
BC342_RS03930	COG1793	dna ligase
BC342_RS03940	COG1012	belongs to the aldehyde dehydrogenase family
BC342_RS03950	COG3424	synthase
BC342_RS03955	COG2124	cytochrome p450
BC342_RS03965	COG1960	acyl-CoA dehydrogenase activity
BC342_RS03975	COG0242	peptide deformylase activity
BC342_RS03980	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BC342_RS03985	COG3442	glutamine amidotransferase
BC342_RS03990	COG0205	6-phosphofructokinase activity
BC342_RS04000	COG3275	phosphorelay sensor kinase activity
BC342_RS04015	COG3279	Response regulator of the LytR AlgR family
BC342_RS04020	COG1522	sequence-specific DNA binding
BC342_RS04025	COG1834	amidinotransferase
BC342_RS04030	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BC342_RS04040	COG0477	Major facilitator Superfamily
BC342_RS04065	COG0740	serine-type endopeptidase activity
BC342_RS04100	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BC342_RS04105	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BC342_RS04110	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BC342_RS04115	COG2226	methyltransferase
BC342_RS04130	COG0456	acetyltransferase
BC342_RS04150	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BC342_RS04175	COG4585	Histidine kinase
BC342_RS04180	COG2197	response regulator
BC342_RS04185	COG1940	carbohydrate kinase activity
BC342_RS04190	COG2188	Transcriptional regulator
BC342_RS04195	COG1595	DNA-templated transcription, initiation
BC342_RS04235	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BC342_RS04240	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BC342_RS04250	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BC342_RS04250	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
BC342_RS04305	COG1028	Short-chain dehydrogenase reductase Sdr
BC342_RS04315	COG0419	ATPase involved in DNA repair
BC342_RS04320	COG0420	3'-5' exonuclease activity
BC342_RS04350	COG1739	Uncharacterized protein family UPF0029
BC342_RS04355	COG1832	CoA-binding protein
BC342_RS04405	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BC342_RS04420	COG1968	undecaprenyl-diphosphatase activity
BC342_RS04445	COG1028	Short-chain dehydrogenase reductase Sdr
BC342_RS04460	COG2318	DinB family
BC342_RS04475	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BC342_RS04515	COG0477	Major facilitator Superfamily
BC342_RS04540	COG2175	clavaminate synthase activity
BC342_RS04545	COG0723	plastoquinol--plastocyanin reductase activity
BC342_RS04625	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
BC342_RS04630	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BC342_RS04635	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BC342_RS04650	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BC342_RS04650	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BC342_RS04660	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BC342_RS04680	COG1716	ATPase activity
BC342_RS04700	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BC342_RS04735	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BC342_RS04745	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BC342_RS04775	COG2018	Roadblock/LC7 domain
BC342_RS04790	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BC342_RS04795	COG2146	nitrite reductase [NAD(P)H] activity
BC342_RS04800	COG1414	Transcriptional regulator
BC342_RS04815	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BC342_RS04850	COG0438	transferase activity, transferring glycosyl groups
BC342_RS04855	COG0438	transferase activity, transferring glycosyl groups
BC342_RS04895	COG2270	Major facilitator Superfamily
BC342_RS04910	COG1216	Glycosyl transferase, family 2
BC342_RS04935	COG1960	acyl-CoA dehydrogenase activity
BC342_RS04980	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BC342_RS04985	COG0140	phosphoribosyl-ATP diphosphatase activity
BC342_RS04990	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BC342_RS04995	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BC342_RS04995	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BC342_RS05000	COG3201	nicotinamide mononucleotide transporter
BC342_RS05010	COG1595	DNA-templated transcription, initiation
BC342_RS05030	COG2223	nitrite transmembrane transporter activity
BC342_RS05065	COG2233	PERMEase
BC342_RS05085	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BC342_RS05115	COG2390	Transcriptional regulator
BC342_RS05120	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BC342_RS05125	COG1653	transport
BC342_RS05160	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BC342_RS05175	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BC342_RS05185	COG1758	RNA polymerase activity
BC342_RS05190	COG0194	GDP metabolic process
BC342_RS05200	COG0284	orotidine-5'-phosphate decarboxylase activity
BC342_RS05205	COG0167	dihydroorotate dehydrogenase activity
BC342_RS05210	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BC342_RS05215	COG0505	Belongs to the CarA family
BC342_RS05225	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BC342_RS05230	COG0540	Belongs to the ATCase OTCase family
BC342_RS05235	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BC342_RS05245	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BC342_RS05250	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BC342_RS05255	COG0006	proline dipeptidase activity
BC342_RS05260	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BC342_RS05265	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BC342_RS05270	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BC342_RS05275	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BC342_RS05285	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BC342_RS05290	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BC342_RS05310	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BC342_RS05325	COG0124	histidyl-tRNA synthetase
BC342_RS05335	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BC342_RS05340	COG1196	nuclear chromosome segregation
BC342_RS05345	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BC342_RS05350	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BC342_RS05355	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BC342_RS05360	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BC342_RS05370	COG2255	four-way junction helicase activity
BC342_RS05375	COG0632	four-way junction helicase activity
BC342_RS05380	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BC342_RS05385	COG0217	transcriptional regulatory protein
BC342_RS05390	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BC342_RS05395	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
BC342_RS05410	COG0438	transferase activity, transferring glycosyl groups
BC342_RS05415	COG1560	Kdo2-lipid A biosynthetic process
BC342_RS05420	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BC342_RS05440	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BC342_RS05445	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BC342_RS05465	COG0395	ABC-type sugar transport system, permease component
BC342_RS05470	COG1175	transmembrane transport
BC342_RS05525	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BC342_RS05575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BC342_RS05580	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BC342_RS05580	COG1648	precorrin-2 dehydrogenase activity
BC342_RS05585	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BC342_RS05600	COG1464	Belongs to the NlpA lipoprotein family
BC342_RS05605	COG2011	ABC-type metal ion transport system permease component
BC342_RS05610	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BC342_RS05640	COG0584	glycerophosphoryl diester phosphodiesterase
BC342_RS05645	COG0204	Acyl-transferase
BC342_RS05645	COG0318	PFAM AMP-dependent synthetase and ligase
BC342_RS05650	COG0477	Major facilitator Superfamily
BC342_RS05665	COG0165	Argininosuccinate lyase
BC342_RS05695	COG1438	arginine binding
BC342_RS05700	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BC342_RS05705	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BC342_RS05710	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BC342_RS05715	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BC342_RS05735	COG0697	spore germination
BC342_RS05745	COG1649	PFAM Uncharacterised BCR, COG1649
BC342_RS05775	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BC342_RS05775	COG0072	phenylalanine-tRNA ligase activity
BC342_RS05780	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BC342_RS05785	COG5002	protein histidine kinase activity
BC342_RS05790	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BC342_RS05795	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BC342_RS05800	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BC342_RS05805	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BC342_RS05855	COG0174	glutamine synthetase
BC342_RS05860	COG2188	Transcriptional regulator
BC342_RS05865	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BC342_RS05880	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BC342_RS05890	COG4176	ABC-type proline glycine betaine transport system permease component
BC342_RS05895	COG4175	Glycine betaine
BC342_RS05895	COG0517	IMP dehydrogenase activity
BC342_RS05900	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BC342_RS05915	COG0564	pseudouridine synthase activity
BC342_RS05950	COG0805	protein transport
BC342_RS05955	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BC342_RS05985	COG0545	Peptidyl-prolyl cis-trans isomerase
BC342_RS05990	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
BC342_RS06005	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
BC342_RS06010	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
BC342_RS06020	COG4122	O-methyltransferase activity
BC342_RS06025	COG1222	aaa ATPase
BC342_RS06045	COG0517	IMP dehydrogenase activity
BC342_RS06045	COG1994	Peptidase M50
BC342_RS06055	COG2197	response regulator
BC342_RS06060	COG4166	transmembrane transport
BC342_RS06070	COG0646	methionine synthase
BC342_RS06070	COG1410	methionine synthase
BC342_RS06080	COG1414	Transcriptional regulator
BC342_RS06085	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BC342_RS06090	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BC342_RS06095	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BC342_RS06105	COG0215	cysteine-tRNA ligase activity
BC342_RS06120	COG0588	phosphoglycerate mutase activity
BC342_RS06125	COG0598	Magnesium transport protein CorA
BC342_RS06135	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BC342_RS06140	COG0667	Aldo Keto reductase
BC342_RS06170	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BC342_RS06180	COG3012	SEC-C Motif Domain Protein
BC342_RS06185	COG2186	Transcriptional regulator
BC342_RS06190	COG3265	gluconokinase activity
BC342_RS06200	COG1028	Short-chain dehydrogenase reductase Sdr
BC342_RS06205	COG1063	alcohol dehydrogenase
BC342_RS06225	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
BC342_RS06230	COG2149	membrane
BC342_RS06255	COG0318	PFAM AMP-dependent synthetase and ligase
BC342_RS06265	COG3876	Protein conserved in bacteria
BC342_RS06280	COG0789	Transcriptional regulator
BC342_RS06300	COG1960	acyl-CoA dehydrogenase activity
BC342_RS06310	COG0640	Transcriptional regulator
BC342_RS06330	COG2851	Citrate transporter
BC342_RS06335	COG0243	molybdopterin cofactor binding
BC342_RS06340	COG1309	transcriptional regulator
BC342_RS06350	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
BC342_RS06355	COG2188	Transcriptional regulator
BC342_RS06385	COG2755	lipolytic protein G-D-S-L family
BC342_RS06410	COG1725	Transcriptional regulator
BC342_RS06465	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BC342_RS06485	COG0765	amino acid transport
BC342_RS06500	COG1799	cell septum assembly
BC342_RS06505	COG1960	acyl-CoA dehydrogenase activity
BC342_RS06510	COG0477	Major facilitator Superfamily
BC342_RS06520	COG0671	phosphoesterase, PA-phosphatase related
BC342_RS06545	COG1160	GTP binding
BC342_RS06555	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BC342_RS06575	COG0494	nUDIX hydrolase
BC342_RS06580	COG1187	pseudouridine synthase activity
BC342_RS06585	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BC342_RS06590	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BC342_RS06605	COG0686	Belongs to the AlaDH PNT family
BC342_RS06615	COG0494	nUDIX hydrolase
BC342_RS06620	COG0504	CTP synthase activity
BC342_RS06625	COG3387	PFAM Glycoside hydrolase 15-related
BC342_RS06640	COG0497	DNA recombination
BC342_RS06665	COG1120	ATPase activity
BC342_RS06670	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BC342_RS06675	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BC342_RS06680	COG0647	UMP catabolic process
BC342_RS06715	COG2094	Belongs to the DNA glycosylase MPG family
BC342_RS06725	COG1881	PFAM PEBP family protein
BC342_RS06745	COG1119	ATPase activity
BC342_RS06760	COG2197	response regulator
BC342_RS06770	COG4221	oxidoreductase activity
BC342_RS06775	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BC342_RS06785	COG1131	(ABC) transporter
BC342_RS06785	COG0842	Transport permease protein
BC342_RS06785	COG1716	ATPase activity
BC342_RS06790	COG3830	Belongs to the UPF0237 family
BC342_RS06790	COG0560	Phosphoserine phosphatase
BC342_RS06795	COG0588	phosphoglycerate mutase activity
BC342_RS06805	COG2807	transmembrane transport
BC342_RS06810	COG2186	Transcriptional regulator
BC342_RS06820	COG1028	Short-chain dehydrogenase reductase Sdr
BC342_RS06850	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BC342_RS06870	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BC342_RS06875	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BC342_RS06915	COG1028	Short-chain dehydrogenase reductase Sdr
BC342_RS06945	COG1024	Enoyl-CoA hydratase
BC342_RS06955	COG0488	(ABC) transporter
BC342_RS06970	COG0235	Class ii aldolase
BC342_RS06985	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BC342_RS06990	COG1492	cobalamin metabolic process
BC342_RS07005	COG1797	cobyrinic acid a,c-diamide synthase activity
BC342_RS07035	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BC342_RS07040	COG0456	acetyltransferase
BC342_RS07045	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BC342_RS07050	COG1917	Cupin 2, conserved barrel domain protein
BC342_RS07055	COG5285	phytanoyl-CoA dioxygenase
BC342_RS07080	COG1414	Transcriptional regulator
BC342_RS07090	COG0768	penicillin binding
BC342_RS07100	COG4677	pectinesterase activity
BC342_RS07105	COG3866	Pectate lyase
BC342_RS07130	COG0395	ABC-type sugar transport system, permease component
BC342_RS07135	COG1175	transmembrane transport
BC342_RS07145	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BC342_RS07150	COG1802	Transcriptional regulator
BC342_RS07155	COG0604	alcohol dehydrogenase
BC342_RS07170	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BC342_RS07175	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BC342_RS07180	COG1349	DNA-binding transcription factor activity
BC342_RS07200	COG1063	alcohol dehydrogenase
BC342_RS07210	COG1309	transcriptional regulator
BC342_RS07230	COG0745	RESPONSE REGULATOR receiver
BC342_RS07235	COG2205	protein histidine kinase activity
BC342_RS07270	COG2171	N-acyltransferase activity
BC342_RS07275	COG3226	Transcriptional regulator
BC342_RS07280	COG2076	Multidrug Resistance protein
BC342_RS07285	COG2151	metal-sulfur cluster biosynthetic enzyme
BC342_RS07290	COG0822	iron-sulfur transferase activity
BC342_RS07295	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BC342_RS07300	COG0396	ATPase activity
BC342_RS07310	COG0719	Fe-S assembly protein
BC342_RS07325	COG2746	aminoglycoside 3-N-acetyltransferase activity
BC342_RS07330	COG1131	(ABC) transporter
BC342_RS07340	COG1612	heme a metabolic process
BC342_RS07360	COG0109	protoheme IX farnesyltransferase activity
BC342_RS07370	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BC342_RS07385	COG0363	glucosamine-6-phosphate deaminase activity
BC342_RS07390	COG0166	Belongs to the GPI family
BC342_RS07400	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BC342_RS07405	COG0149	triose-phosphate isomerase activity
BC342_RS07410	COG0126	phosphoglycerate kinase activity
BC342_RS07415	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BC342_RS07420	COG1481	regulation of sporulation
BC342_RS07425	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BC342_RS07430	COG1660	Displays ATPase and GTPase activities
BC342_RS07435	COG0322	excinuclease ABC activity
BC342_RS07460	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BC342_RS07475	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BC342_RS07480	COG0387	Pfam Sodium calcium exchanger
BC342_RS07500	COG0556	nucleotide-excision repair
BC342_RS07510	COG0584	glycerophosphoryl diester phosphodiesterase
BC342_RS07515	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BC342_RS07535	COG2313	pseudouridylate synthase activity
BC342_RS07540	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BC342_RS07545	COG2226	methyltransferase
BC342_RS07590	COG0402	S-adenosylhomocysteine deaminase activity
BC342_RS07615	COG1309	transcriptional regulator
BC342_RS07620	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BC342_RS07645	COG0667	Aldo Keto reductase
BC342_RS07655	COG2267	carboxylic ester hydrolase activity
BC342_RS07670	COG2226	methyltransferase
BC342_RS07680	COG0237	dephospho-CoA kinase activity
BC342_RS07695	COG2226	methyltransferase
BC342_RS07725	COG2050	protein possibly involved in aromatic compounds catabolism
BC342_RS07770	COG0737	Belongs to the 5'-nucleotidase family
BC342_RS07790	COG0287	Prephenate dehydrogenase
BC342_RS07790	COG1605	Chorismate mutase
BC342_RS07805	COG2304	oxidoreductase activity
BC342_RS07825	COG0070	glutamate synthase
BC342_RS07825	COG0069	glutamate synthase activity
BC342_RS07825	COG0067	glutamate synthase
BC342_RS07835	COG1397	ADP-ribosylglycohydrolase
BC342_RS07855	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BC342_RS07860	COG2301	Belongs to the HpcH HpaI aldolase family
BC342_RS07865	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BC342_RS07875	COG0159	tryptophan synthase activity
BC342_RS07880	COG0133	tryptophan synthase activity
BC342_RS07885	COG0134	indole-3-glycerol-phosphate synthase activity
BC342_RS07910	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BC342_RS07925	COG0107	imidazoleglycerol-phosphate synthase activity
BC342_RS07930	COG0251	oxidation-reduction process
BC342_RS07935	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BC342_RS07940	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BC342_RS07945	COG0131	Imidazoleglycerol-phosphate dehydratase
BC342_RS07950	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BC342_RS07955	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BC342_RS07975	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BC342_RS07995	COG1432	Conserved Protein
BC342_RS08000	COG0587	DNA-directed DNA polymerase activity
BC342_RS08045	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BC342_RS08055	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BC342_RS08060	COG3599	regulation of cell shape
BC342_RS08070	COG1799	cell septum assembly
BC342_RS08075	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BC342_RS08080	COG1496	oxidoreductase activity
BC342_RS08090	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BC342_RS08095	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BC342_RS08105	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BC342_RS08110	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BC342_RS08120	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BC342_RS08125	COG0768	penicillin binding
BC342_RS08135	COG0275	rRNA processing
BC342_RS08145	COG0714	Associated with various cellular activities
BC342_RS08175	COG1309	transcriptional regulator
BC342_RS08195	COG0352	thiamine-phosphate diphosphorylase activity
BC342_RS08205	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BC342_RS08210	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BC342_RS08210	COG2022	thiamine diphosphate biosynthetic process
BC342_RS08220	COG2022	thiamine diphosphate biosynthetic process
BC342_RS08225	COG2815	serine threonine protein kinase
BC342_RS08225	COG0515	serine threonine protein kinase
BC342_RS08230	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BC342_RS08235	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BC342_RS08240	COG2193	ferroxidase activity
BC342_RS08250	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
BC342_RS08260	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BC342_RS08265	COG0205	6-phosphofructokinase activity
BC342_RS08270	COG2197	response regulator
BC342_RS08300	COG1940	carbohydrate kinase activity
BC342_RS08310	COG0003	Pfam Anion-transporting ATPase
BC342_RS08375	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BC342_RS08380	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BC342_RS08385	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BC342_RS08390	COG0723	plastoquinol--plastocyanin reductase activity
BC342_RS08395	COG2010	Cytochrome c
BC342_RS08400	COG1845	cytochrome c oxidase, subunit III
BC342_RS08410	COG1376	ErfK ybiS ycfS ynhG family protein
BC342_RS08420	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BC342_RS08425	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BC342_RS08430	COG1104	cysteine desulfurase activity
BC342_RS08435	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BC342_RS08470	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BC342_RS08475	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BC342_RS08480	COG2197	response regulator
BC342_RS08485	COG4585	Histidine kinase
BC342_RS08505	COG2226	methyltransferase
BC342_RS08510	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BC342_RS08530	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BC342_RS08535	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
BC342_RS08545	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BC342_RS08550	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BC342_RS08555	COG0508	dehydrogenase complex catalyzes the overall conversion of
BC342_RS08565	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BC342_RS08625	COG0300	oxidoreductase activity
BC342_RS08640	COG0321	lipoyl(octanoyl) transferase activity
BC342_RS08645	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BC342_RS08665	COG0174	glutamine synthetase
BC342_RS08675	COG0702	epimerase
BC342_RS08680	COG1733	regulation of RNA biosynthetic process
BC342_RS08685	COG0501	Belongs to the peptidase M48B family
BC342_RS08715	COG0745	RESPONSE REGULATOR receiver
BC342_RS08725	COG2197	response regulator
BC342_RS08750	COG1309	transcriptional regulator
BC342_RS08775	COG3833	ABC-type maltose transport systems, permease component
BC342_RS08780	COG1175	transmembrane transport
BC342_RS08785	COG1653	transport
BC342_RS08790	COG1609	Transcriptional regulator
BC342_RS08800	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BC342_RS08805	COG2161	toxin-antitoxin pair type II binding
BC342_RS08810	COG4115	mRNA cleavage
BC342_RS08820	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BC342_RS08820	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BC342_RS08835	COG0174	glutamine synthetase
BC342_RS08845	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BC342_RS08875	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BC342_RS08895	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BC342_RS08900	COG2814	Major facilitator Superfamily
BC342_RS08910	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BC342_RS08930	COG1994	Peptidase M50
BC342_RS08985	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BC342_RS08990	COG1120	ATPase activity
BC342_RS09015	COG2197	response regulator
BC342_RS09025	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BC342_RS09030	COG2814	Major facilitator Superfamily
BC342_RS09110	COG0515	serine threonine protein kinase
BC342_RS09110	COG2815	serine threonine protein kinase
BC342_RS09115	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BC342_RS09125	COG0431	NADPH-dependent FMN reductase
BC342_RS09140	COG2197	response regulator
BC342_RS09145	COG4585	Histidine kinase
BC342_RS09150	COG0586	Pfam SNARE associated Golgi protein
BC342_RS09175	COG0583	DNA-binding transcription factor activity
BC342_RS09195	COG1595	DNA-templated transcription, initiation
BC342_RS09220	COG3903	Transcriptional regulator
BC342_RS09220	COG3629	intracellular signal transduction
BC342_RS09240	COG1252	NADH dehydrogenase
BC342_RS09270	COG3022	response to hydroperoxide
BC342_RS09275	COG0800	Aldolase
BC342_RS09290	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BC342_RS09300	COG2030	dehydratase
BC342_RS09305	COG4585	Histidine kinase
BC342_RS09310	COG2197	response regulator
BC342_RS09320	COG0477	Major facilitator Superfamily
BC342_RS09355	COG0438	transferase activity, transferring glycosyl groups
BC342_RS09360	COG1309	transcriptional regulator
BC342_RS09365	COG1657	PFAM Prenyltransferase squalene oxidase
BC342_RS09380	COG3845	ABC transporter
BC342_RS09430	COG2318	DinB family
BC342_RS09500	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BC342_RS09520	COG0596	Alpha beta hydrolase
BC342_RS09570	COG0586	Pfam SNARE associated Golgi protein
BC342_RS09580	COG1358	cellular component organization or biogenesis
BC342_RS09625	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BC342_RS09635	COG0477	Major facilitator Superfamily
BC342_RS09640	COG1309	transcriptional regulator
BC342_RS09655	COG0789	Transcriptional regulator
BC342_RS09685	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BC342_RS09690	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BC342_RS09695	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BC342_RS09725	COG1764	response to oxidative stress
BC342_RS09730	COG2130	NADP-dependent
BC342_RS09785	COG1129	ABC transporter
BC342_RS09790	COG4214	carbohydrate transport
BC342_RS09805	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BC342_RS09830	COG0395	ABC-type sugar transport system, permease component
BC342_RS09835	COG1175	transmembrane transport
BC342_RS09865	COG3386	PFAM SMP-30 Gluconolaconase
BC342_RS09870	COG1414	Transcriptional regulator
BC342_RS09880	COG2186	Transcriptional regulator
BC342_RS09890	COG0318	PFAM AMP-dependent synthetase and ligase
BC342_RS09895	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BC342_RS09895	COG0825	malonyl-CoA metabolic process
BC342_RS09920	COG1077	Cell shape determining protein MreB Mrl
BC342_RS09995	COG1674	ftsk spoiiie
BC342_RS10005	COG0464	growth
BC342_RS10050	COG1070	Carbohydrate kinase
BC342_RS10065	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BC342_RS10070	COG0358	DNA primase activity
BC342_RS10080	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BC342_RS10090	COG2949	membrane
BC342_RS10095	COG0243	molybdopterin cofactor binding
BC342_RS10105	COG0583	DNA-binding transcription factor activity
BC342_RS10175	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BC342_RS10175	COG0574	Belongs to the PEP-utilizing enzyme family
BC342_RS10205	COG0423	glycine-tRNA ligase activity
BC342_RS10210	COG3443	Belongs to the bacterial solute-binding protein 9 family
BC342_RS10210	COG0803	Belongs to the bacterial solute-binding protein 9 family
BC342_RS10215	COG1120	ATPase activity
BC342_RS10220	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BC342_RS10230	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BC342_RS10235	COG1381	Involved in DNA repair and RecF pathway recombination
BC342_RS10300	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BC342_RS10325	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BC342_RS10335	COG2315	Protein conserved in bacteria
BC342_RS10345	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BC342_RS10350	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BC342_RS10355	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BC342_RS10360	COG1234	tRNA 3'-trailer cleavage
BC342_RS10365	COG0537	adenosine 5'-monophosphoramidase activity
BC342_RS10370	COG0793	Belongs to the peptidase S41A family
BC342_RS10370	COG4946	Tricorn protease homolog
BC342_RS10385	COG2070	2-Nitropropane dioxygenase
BC342_RS10390	COG0484	heat shock protein binding
BC342_RS10395	COG1420	regulation of RNA biosynthetic process
BC342_RS10430	COG0481	GTPase activity
BC342_RS10435	COG0268	Binds directly to 16S ribosomal RNA
BC342_RS10455	COG2353	YceI-like domain
BC342_RS10460	COG1234	tRNA 3'-trailer cleavage
BC342_RS10490	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BC342_RS10520	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BC342_RS10590	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BC342_RS10610	COG0297	glycogen (starch) synthase activity
BC342_RS10620	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BC342_RS10680	COG1555	photosystem II stabilization
BC342_RS10685	COG1307	EDD domain protein, DegV family
BC342_RS10695	COG0495	leucyl-tRNA aminoacylation
BC342_RS10705	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BC342_RS10725	COG0588	phosphoglycerate mutase activity
BC342_RS10730	COG0799	negative regulation of ribosome biogenesis
BC342_RS10740	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BC342_RS10745	COG0501	Belongs to the peptidase M48B family
BC342_RS10760	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BC342_RS10770	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BC342_RS10780	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BC342_RS10785	COG0463	Glycosyl transferase, family 2
BC342_RS10785	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BC342_RS10790	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BC342_RS10800	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BC342_RS10805	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BC342_RS10810	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BC342_RS10815	COG1530	ribonuclease E activity
BC342_RS10840	COG0772	Belongs to the SEDS family
BC342_RS10845	COG0768	penicillin binding
BC342_RS10860	COG1077	Cell shape determining protein MreB Mrl
BC342_RS10865	COG0105	UTP biosynthetic process
BC342_RS10875	COG0285	dihydrofolate synthase activity
BC342_RS10880	COG0525	valine-tRNA ligase activity
BC342_RS10890	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BC342_RS10895	COG0740	serine-type endopeptidase activity
BC342_RS10900	COG0740	serine-type endopeptidase activity
BC342_RS10905	COG0544	peptidyl-prolyl cis-trans isomerase activity
BC342_RS10930	COG3594	Acyltransferase
BC342_RS10945	COG4552	Acetyltransferase involved in intracellular survival and related
BC342_RS10960	COG1113	amino acid transport
BC342_RS10965	COG1268	BioY protein
BC342_RS10970	COG1113	amino acid transport
BC342_RS10985	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BC342_RS11070	COG0668	transmembrane transport
BC342_RS11075	COG1940	carbohydrate kinase activity
BC342_RS11085	COG1175	transmembrane transport
BC342_RS11095	COG1486	melibiose metabolic process
BC342_RS11110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BC342_RS11145	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BC342_RS11165	COG0577	efflux transmembrane transporter activity
BC342_RS11165	COG1136	(ABC) transporter
BC342_RS11290	COG3850	Histidine kinase
BC342_RS11325	COG0537	adenosine 5'-monophosphoramidase activity
BC342_RS11335	COG2249	NAD(P)H dehydrogenase (quinone) activity
BC342_RS11365	COG0629	single-stranded DNA binding
BC342_RS11390	COG1136	(ABC) transporter
BC342_RS11400	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BC342_RS11415	COG2304	oxidoreductase activity
BC342_RS11450	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BC342_RS11470	COG0438	transferase activity, transferring glycosyl groups
BC342_RS11515	COG1022	Amp-dependent synthetase and ligase
BC342_RS11550	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BC342_RS11580	COG1131	(ABC) transporter
BC342_RS11590	COG1595	DNA-templated transcription, initiation
BC342_RS11595	COG2072	flavoprotein involved in K transport
BC342_RS11610	COG0477	Major facilitator Superfamily
BC342_RS11635	COG1595	DNA-templated transcription, initiation
BC342_RS11650	COG1129	ABC transporter
BC342_RS11655	COG1879	ABC-type sugar transport system periplasmic component
BC342_RS11660	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BC342_RS11665	COG1869	D-ribose catabolic process
BC342_RS11705	COG1472	Belongs to the glycosyl hydrolase 3 family
BC342_RS11770	COG1309	transcriptional regulator
BC342_RS11780	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BC342_RS11785	COG2356	endonuclease I
BC342_RS11810	COG1946	Acyl-CoA thioesterase
BC342_RS11820	COG1309	transcriptional regulator
BC342_RS11825	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BC342_RS11840	COG1960	acyl-CoA dehydrogenase activity
BC342_RS11855	COG3486	L-lysine 6-monooxygenase (NADPH) activity
BC342_RS11880	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BC342_RS11885	COG0589	response to stress
BC342_RS11895	COG4977	sequence-specific DNA binding
BC342_RS11900	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
BC342_RS11920	COG0395	ABC-type sugar transport system, permease component
BC342_RS11945	COG3979	chitinase
BC342_RS11955	COG0745	RESPONSE REGULATOR receiver
BC342_RS11965	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BC342_RS12055	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BC342_RS12100	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BC342_RS12115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BC342_RS12120	COG0765	amino acid transport
BC342_RS12125	COG0765	amino acid transport
BC342_RS12130	COG1126	abc transporter atp-binding protein
BC342_RS12145	COG3397	chitin binding
BC342_RS12195	COG0673	inositol 2-dehydrogenase activity
BC342_RS12200	COG4702	Belongs to the UPF0303 family
BC342_RS12225	COG1309	transcriptional regulator
BC342_RS12230	COG1028	Short-chain dehydrogenase reductase Sdr
BC342_RS12250	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BC342_RS12255	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BC342_RS12340	COG1063	alcohol dehydrogenase
BC342_RS12350	COG1902	pentaerythritol trinitrate reductase activity
BC342_RS12440	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BC342_RS12465	COG2733	membrane
BC342_RS12480	COG3119	arylsulfatase activity
BC342_RS12535	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BC342_RS12545	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BC342_RS12550	COG2353	YceI-like domain
BC342_RS12555	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BC342_RS12560	COG1263	PTS System
BC342_RS12565	COG1263	PTS System
BC342_RS12570	COG1234	tRNA 3'-trailer cleavage
BC342_RS12605	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BC342_RS12615	COG1335	isochorismatase
BC342_RS12635	COG1714	RDD family
BC342_RS12650	COG0277	FAD linked oxidase domain protein
BC342_RS12660	COG3185	4-Hydroxyphenylpyruvate dioxygenase
BC342_RS12670	COG1174	glycine betaine transport
BC342_RS12680	COG1174	glycine betaine transport
BC342_RS12690	COG3480	Lon protease (S16) C-terminal proteolytic domain
BC342_RS12720	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BC342_RS12735	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BC342_RS12740	COG0395	ABC-type sugar transport system, permease component
BC342_RS12745	COG1175	transmembrane transport
BC342_RS12750	COG1653	transport
BC342_RS12760	COG1678	Uncharacterized ACR, COG1678
BC342_RS12765	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BC342_RS12770	COG0776	regulation of translation
BC342_RS12780	COG3973	AAA domain
BC342_RS12805	COG2223	nitrite transmembrane transporter activity
BC342_RS12845	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BC342_RS12850	COG0793	Belongs to the peptidase S41A family
BC342_RS12860	COG2884	Cell division ATP-binding protein ftsE
BC342_RS12875	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BC342_RS12880	COG0515	serine threonine protein kinase
BC342_RS12885	COG0515	serine threonine protein kinase
BC342_RS12905	COG0395	ABC-type sugar transport system, permease component
BC342_RS12910	COG1216	Glycosyl transferase, family 2
BC342_RS12920	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BC342_RS12930	COG1764	response to oxidative stress
BC342_RS12935	COG1846	Transcriptional regulator
BC342_RS12950	COG2318	DinB family
BC342_RS12975	COG1134	teichoic acid transport
BC342_RS12980	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BC342_RS12985	COG2902	Dehydrogenase
BC342_RS13005	COG0653	protein targeting
BC342_RS13015	COG3214	Protein conserved in bacteria
BC342_RS13020	COG2197	response regulator
BC342_RS13025	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BC342_RS13035	COG0823	Involved in the tonB-independent uptake of proteins
BC342_RS13040	COG5000	phosphorelay sensor kinase activity
BC342_RS13040	COG5002	protein histidine kinase activity
BC342_RS13045	COG0745	RESPONSE REGULATOR receiver
BC342_RS13050	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BC342_RS13070	COG0714	Associated with various cellular activities
BC342_RS13115	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BC342_RS13125	COG1482	cell wall glycoprotein biosynthetic process
BC342_RS13135	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BC342_RS13140	COG1620	l-lactate permease
BC342_RS13185	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BC342_RS13190	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
BC342_RS13190	COG0778	Nitroreductase
BC342_RS13215	COG1316	TRANSCRIPTIONal
BC342_RS13225	COG1316	TRANSCRIPTIONal
BC342_RS13235	COG1316	TRANSCRIPTIONal
BC342_RS13240	COG1316	TRANSCRIPTIONal
BC342_RS13245	COG1316	TRANSCRIPTIONal
BC342_RS13260	COG1960	acyl-CoA dehydrogenase activity
BC342_RS13265	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BC342_RS13280	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BC342_RS13295	COG2205	protein histidine kinase activity
BC342_RS13300	COG0745	RESPONSE REGULATOR receiver
BC342_RS13305	COG3104	oligopeptide transport
BC342_RS13315	COG1366	Belongs to the anti-sigma-factor antagonist family
BC342_RS13320	COG1191	sigma factor activity
BC342_RS13325	COG1228	amidohydrolase
BC342_RS13335	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BC342_RS13340	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BC342_RS13370	COG2755	lipolytic protein G-D-S-L family
BC342_RS13375	COG0183	Belongs to the thiolase family
BC342_RS13410	COG1136	(ABC) transporter
BC342_RS13415	COG0577	efflux transmembrane transporter activity
BC342_RS13420	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BC342_RS13425	COG1252	NADH dehydrogenase
BC342_RS13445	COG0148	phosphopyruvate hydratase activity
BC342_RS13490	COG0577	efflux transmembrane transporter activity
BC342_RS13495	COG1136	(ABC) transporter
BC342_RS13525	COG4585	Histidine kinase
BC342_RS13535	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BC342_RS13540	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BC342_RS13545	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BC342_RS13550	COG0193	aminoacyl-tRNA hydrolase activity
BC342_RS13560	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BC342_RS13570	COG1309	transcriptional regulator
BC342_RS13580	COG4106	trans-aconitate 2-methyltransferase activity
BC342_RS13590	COG2197	response regulator
BC342_RS13630	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BC342_RS13670	COG0488	(ABC) transporter
BC342_RS13680	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BC342_RS13685	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BC342_RS13695	COG0084	hydrolase, TatD family'
BC342_RS13725	COG1028	Short-chain dehydrogenase reductase Sdr
BC342_RS13740	COG0300	oxidoreductase activity
BC342_RS13775	COG0310	cobalt ion transport
BC342_RS13785	COG1122	ATPase activity
BC342_RS13790	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BC342_RS13800	COG0442	prolyl-tRNA aminoacylation
BC342_RS13815	COG2409	Drug exporters of the RND superfamily
BC342_RS13825	COG4946	Tricorn protease homolog
BC342_RS13825	COG0793	Belongs to the peptidase S41A family
BC342_RS13840	COG2267	carboxylic ester hydrolase activity
BC342_RS13845	COG2072	flavoprotein involved in K transport
BC342_RS13855	COG0708	Exodeoxyribonuclease III
BC342_RS13880	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BC342_RS13885	COG0315	cyclic pyranopterin monophosphate synthase activity
BC342_RS13885	COG0521	Mo-molybdopterin cofactor biosynthetic process
BC342_RS13890	COG0315	cyclic pyranopterin monophosphate synthase activity
BC342_RS13900	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BC342_RS13905	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BC342_RS13930	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BC342_RS13940	COG1970	mechanosensitive ion channel activity
BC342_RS13950	COG3191	aminopeptidase activity
BC342_RS13960	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BC342_RS13960	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BC342_RS13960	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BC342_RS13970	COG1349	DNA-binding transcription factor activity
BC342_RS13985	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BC342_RS13990	COG1247	-acetyltransferase
BC342_RS13995	COG3384	dioxygenase
BC342_RS14000	COG1846	Transcriptional regulator
BC342_RS14040	COG2205	protein histidine kinase activity
BC342_RS14045	COG0745	RESPONSE REGULATOR receiver
BC342_RS14050	COG2208	phosphoserine phosphatase activity
BC342_RS14065	COG0386	Belongs to the glutathione peroxidase family
BC342_RS14085	COG1686	Belongs to the peptidase S11 family
BC342_RS14120	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
BC342_RS14140	COG3629	intracellular signal transduction
BC342_RS14140	COG3903	Transcriptional regulator
BC342_RS14155	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BC342_RS14155	COG0515	serine threonine protein kinase
BC342_RS14165	COG1309	transcriptional regulator
BC342_RS14175	COG0259	pyridoxamine-phosphate oxidase activity
BC342_RS14210	COG1366	Belongs to the anti-sigma-factor antagonist family
BC342_RS14215	COG1595	DNA-templated transcription, initiation
BC342_RS14255	COG1131	(ABC) transporter
BC342_RS14265	COG0596	Alpha beta hydrolase
BC342_RS14265	COG2945	thiolester hydrolase activity
BC342_RS14275	COG4821	SIS domain
BC342_RS14290	COG0259	pyridoxamine-phosphate oxidase activity
BC342_RS14305	COG0318	PFAM AMP-dependent synthetase and ligase
BC342_RS14320	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BC342_RS14355	COG0604	alcohol dehydrogenase
BC342_RS14360	COG1309	transcriptional regulator
BC342_RS14365	COG1733	regulation of RNA biosynthetic process
BC342_RS14370	COG0604	alcohol dehydrogenase
BC342_RS14395	COG2318	DinB family
BC342_RS14400	COG0247	lactate metabolic process
BC342_RS14400	COG0277	FAD linked oxidase domain protein
BC342_RS14405	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BC342_RS14475	COG2197	response regulator
BC342_RS14505	COG0667	Aldo Keto reductase
BC342_RS14535	COG2252	PERMEase
BC342_RS14545	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BC342_RS14560	COG2814	Major facilitator Superfamily
BC342_RS14570	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BC342_RS14575	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
BC342_RS14580	COG1278	Cold shock
BC342_RS14605	COG1061	Type III restriction enzyme res subunit
BC342_RS14615	COG3973	AAA domain
BC342_RS14650	COG1737	Transcriptional regulator
BC342_RS14655	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BC342_RS14665	COG1028	Short-chain dehydrogenase reductase Sdr
BC342_RS14670	COG1309	transcriptional regulator
BC342_RS14685	COG0459	protein refolding
BC342_RS14690	COG1278	Cold shock
BC342_RS14705	COG0463	Glycosyl transferase, family 2
BC342_RS14715	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
BC342_RS14735	COG1940	carbohydrate kinase activity
BC342_RS14745	COG1105	Belongs to the carbohydrate kinase PfkB family
BC342_RS14755	COG3300	MHYT domain
BC342_RS14755	COG5001	Diguanylate cyclase
BC342_RS14775	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BC342_RS14790	COG1064	alcohol dehydrogenase
BC342_RS14795	COG1309	transcriptional regulator
BC342_RS14810	COG1215	transferase activity, transferring glycosyl groups
BC342_RS14815	COG0604	alcohol dehydrogenase
BC342_RS14825	COG1028	Short-chain dehydrogenase reductase Sdr
BC342_RS14860	COG0702	epimerase
BC342_RS14870	COG2197	response regulator
BC342_RS14885	COG0464	growth
BC342_RS14985	COG2890	protein-(glutamine-N5) methyltransferase activity
BC342_RS14995	COG3842	ATPase activity
BC342_RS15015	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BC342_RS15065	COG0215	cysteine-tRNA ligase activity
BC342_RS15070	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BC342_RS15075	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BC342_RS15080	COG1329	Transcriptional regulator
BC342_RS15095	COG5002	protein histidine kinase activity
BC342_RS15125	COG3104	oligopeptide transport
BC342_RS15180	COG2130	NADP-dependent
BC342_RS15200	COG2188	Transcriptional regulator
BC342_RS15245	COG0588	phosphoglycerate mutase activity
BC342_RS15270	COG0438	transferase activity, transferring glycosyl groups
BC342_RS15310	COG0371	Dehydrogenase
BC342_RS15330	COG0546	phosphoglycolate phosphatase activity
BC342_RS15335	COG2188	Transcriptional regulator
BC342_RS15340	COG2188	Transcriptional regulator
BC342_RS15360	COG1490	D-aminoacyl-tRNA deacylase activity
BC342_RS15365	COG0354	folic acid binding
BC342_RS15370	COG0735	belongs to the Fur family
BC342_RS15375	COG3485	protocatechuate 3,4-dioxygenase
BC342_RS15415	COG2897	thiosulfate sulfurtransferase activity
BC342_RS15440	COG0745	RESPONSE REGULATOR receiver
BC342_RS15445	COG1609	Transcriptional regulator
BC342_RS15450	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BC342_RS15455	COG0745	RESPONSE REGULATOR receiver
BC342_RS15475	COG0456	acetyltransferase
BC342_RS15505	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BC342_RS15530	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BC342_RS15535	COG0306	phosphate transporter
BC342_RS15545	COG1937	Protein conserved in bacteria
BC342_RS15560	COG0671	phosphoesterase, PA-phosphatase related
BC342_RS15565	COG0739	heme binding
BC342_RS15565	COG1196	nuclear chromosome segregation
BC342_RS15565	COG0741	lytic transglycosylase activity
BC342_RS15605	COG4585	Histidine kinase
BC342_RS15610	COG2197	response regulator
BC342_RS15650	COG1252	NADH dehydrogenase
BC342_RS15680	COG0579	oxidoreductase
BC342_RS15685	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BC342_RS15695	COG0667	Aldo Keto reductase
BC342_RS15715	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BC342_RS15715	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BC342_RS15720	COG1201	RNA secondary structure unwinding
BC342_RS15815	COG1414	Transcriptional regulator
BC342_RS15835	COG2860	membrane
BC342_RS15865	COG0513	Belongs to the DEAD box helicase family
BC342_RS15900	COG2197	response regulator
BC342_RS15915	COG0318	PFAM AMP-dependent synthetase and ligase
BC342_RS15970	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BC342_RS15975	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BC342_RS15990	COG1643	Atp-dependent helicase
BC342_RS16010	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BC342_RS16020	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BC342_RS16045	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BC342_RS16050	COG0047	phosphoribosylformylglycinamidine synthase activity
BC342_RS16055	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BC342_RS16085	COG3851	Histidine kinase
BC342_RS16090	COG2197	response regulator
BC342_RS16100	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BC342_RS16115	COG0151	Belongs to the GarS family
BC342_RS16150	COG1028	Short-chain dehydrogenase reductase Sdr
BC342_RS16200	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BC342_RS16235	COG1191	sigma factor activity
BC342_RS16240	COG1191	sigma factor activity
BC342_RS16260	COG2353	YceI-like domain
BC342_RS16280	COG3467	pyridoxamine 5'-phosphate
BC342_RS16290	COG0477	Major facilitator Superfamily
BC342_RS16310	COG2205	protein histidine kinase activity
BC342_RS16315	COG0745	RESPONSE REGULATOR receiver
BC342_RS16345	COG1733	regulation of RNA biosynthetic process
BC342_RS16350	COG0768	penicillin binding
BC342_RS16375	COG2188	Transcriptional regulator
BC342_RS16440	COG0582	viral genome integration into host DNA
BC342_RS16465	COG1309	transcriptional regulator
BC342_RS16470	COG2814	Major facilitator Superfamily
BC342_RS16475	COG0318	PFAM AMP-dependent synthetase and ligase
BC342_RS16480	COG1595	DNA-templated transcription, initiation
BC342_RS16505	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BC342_RS16520	COG0653	protein targeting
BC342_RS16540	COG0006	proline dipeptidase activity
BC342_RS16560	COG1999	signal sequence binding
BC342_RS16575	COG2837	iron assimilation
BC342_RS16580	COG0077	Prephenate dehydratase
BC342_RS16585	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BC342_RS16590	COG0561	phosphatase activity
BC342_RS16615	COG1131	(ABC) transporter
BC342_RS16625	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
BC342_RS16635	COG0561	phosphatase activity
BC342_RS16640	COG0739	heme binding
BC342_RS16655	COG1294	oxidase, subunit
BC342_RS16660	COG1271	oxidase subunit
BC342_RS16665	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BC342_RS16670	COG1609	Transcriptional regulator
BC342_RS16675	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BC342_RS16690	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BC342_RS16715	COG0662	Cupin 2, conserved barrel domain protein
BC342_RS16720	COG1950	PFAM Membrane protein of
BC342_RS16725	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BC342_RS16730	COG0626	cystathionine gamma-synthase activity
BC342_RS16755	COG2814	Major facilitator Superfamily
BC342_RS16775	COG2197	response regulator
BC342_RS16780	COG4585	Histidine kinase
BC342_RS16790	COG0305	Participates in initiation and elongation during chromosome replication
BC342_RS16800	COG0359	binds to the 23S rRNA
BC342_RS16805	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BC342_RS16810	COG0629	single-stranded DNA binding
BC342_RS16815	COG0360	Binds together with S18 to 16S ribosomal RNA
BC342_RS16840	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BC342_RS16885	COG1595	DNA-templated transcription, initiation
BC342_RS16895	COG0492	ferredoxin-NADP+ reductase activity
BC342_RS16900	COG3118	belongs to the thioredoxin family
BC342_RS16915	COG1192	Involved in chromosome partitioning
BC342_RS16920	COG0357	Ribosomal RNA small subunit methyltransferase G
BC342_RS16930	COG0706	membrane insertase activity
BC342_RS16935	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BC342_RS16940	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BC342_RS16945	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BC342_RS16950	COG0592	DNA-directed DNA polymerase activity
BC342_RS16955	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BC342_RS16960	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BC342_RS16965	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
BC342_RS16970	COG0187	DNA topoisomerase II activity
BC342_RS16975	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BC342_RS17000	COG2319	Wd-40 repeat
BC342_RS17000	COG4249	Peptidase C14 caspase catalytic subunit p20
BC342_RS17020	COG0515	serine threonine protein kinase
BC342_RS17035	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BC342_RS17050	COG0705	Rhomboid family
BC342_RS17075	COG3764	Sortase (surface protein transpeptidase)
BC342_RS17080	COG0515	serine threonine protein kinase
BC342_RS17085	COG0768	penicillin binding
BC342_RS17100	COG1716	ATPase activity
BC342_RS17105	COG1716	ATPase activity
BC342_RS17150	COG1250	3-hydroxyacyl-CoA dehydrogenase
BC342_RS17155	COG1309	transcriptional regulator
BC342_RS17160	COG1522	sequence-specific DNA binding
BC342_RS17205	COG3321	synthase
BC342_RS17205	COG1028	Short-chain dehydrogenase reductase Sdr
BC342_RS17205	COG0604	alcohol dehydrogenase
BC342_RS17220	COG0515	serine threonine protein kinase
BC342_RS17225	COG0515	serine threonine protein kinase
BC342_RS17245	COG0022	dehydrogenase e1 component
BC342_RS17250	COG0508	dehydrogenase complex catalyzes the overall conversion of
BC342_RS17295	COG1362	aminopeptidase activity
BC342_RS17300	COG1960	acyl-CoA dehydrogenase activity
BC342_RS17310	COG1741	Belongs to the pirin family
BC342_RS17390	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BC342_RS17440	COG0366	Alpha amylase catalytic
BC342_RS17475	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BC342_RS17505	COG4585	Histidine kinase
BC342_RS17510	COG2197	response regulator
BC342_RS17515	COG1136	(ABC) transporter
BC342_RS17530	COG0596	Alpha beta hydrolase
BC342_RS17540	COG0577	efflux transmembrane transporter activity
BC342_RS17540	COG1136	(ABC) transporter
BC342_RS17595	COG0745	RESPONSE REGULATOR receiver
BC342_RS17600	COG5002	protein histidine kinase activity
BC342_RS17635	COG0513	Belongs to the DEAD box helicase family
BC342_RS17640	COG1278	Cold shock
BC342_RS17645	COG0667	Aldo Keto reductase
BC342_RS17740	COG1733	regulation of RNA biosynthetic process
BC342_RS17820	COG0596	Alpha beta hydrolase
BC342_RS17860	COG0717	Belongs to the dCTP deaminase family
BC342_RS17865	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
BC342_RS17880	COG0247	lactate metabolic process
BC342_RS17880	COG2181	nitrate reductase activity
BC342_RS17885	COG0443	Heat shock 70 kDa protein
BC342_RS17890	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BC342_RS17895	COG0484	heat shock protein binding
BC342_RS17900	COG0789	Transcriptional regulator
BC342_RS17905	COG4213	ABC transporter substrate-binding protein
BC342_RS17935	COG0542	response to heat
BC342_RS17950	COG0596	Alpha beta hydrolase
BC342_RS17975	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BC342_RS17990	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BC342_RS17995	COG0191	fructose-bisphosphate aldolase activity
BC342_RS18000	COG0477	Major facilitator Superfamily
BC342_RS18015	COG3844	kynureninase activity
BC342_RS18035	COG4585	Histidine kinase
BC342_RS18040	COG2197	response regulator
BC342_RS18045	COG4585	Histidine kinase
BC342_RS18050	COG2197	response regulator
BC342_RS18065	COG3559	Exporter of polyketide antibiotics
BC342_RS18070	COG1131	(ABC) transporter
BC342_RS18085	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BC342_RS18105	COG1802	Transcriptional regulator
BC342_RS18110	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BC342_RS18125	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BC342_RS18130	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BC342_RS18140	COG2124	cytochrome p450
BC342_RS18180	COG1595	DNA-templated transcription, initiation
BC342_RS18205	COG0640	Transcriptional regulator
BC342_RS18210	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BC342_RS18220	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BC342_RS18230	COG1585	Membrane protein implicated in regulation of membrane protease activity
BC342_RS18235	COG2268	Band 7 protein
BC342_RS18245	COG3655	Transcriptional regulator
BC342_RS18255	COG3263	regulation of cellular component size
BC342_RS18260	COG0475	glutathione-regulated potassium exporter activity
BC342_RS18315	COG1136	(ABC) transporter
BC342_RS18350	COG2274	protein secretion by the type I secretion system
BC342_RS18370	COG1131	(ABC) transporter
BC342_RS18385	COG4152	abc transporter atp-binding protein
BC342_RS18390	COG1668	transmembrane transport
BC342_RS18400	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BC342_RS18400	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
BC342_RS18425	COG1408	metallophosphoesterase
BC342_RS18435	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BC342_RS18445	COG0003	Pfam Anion-transporting ATPase
BC342_RS18460	COG0596	Alpha beta hydrolase
BC342_RS18470	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BC342_RS18485	COG0494	nUDIX hydrolase
BC342_RS18495	COG0596	Alpha beta hydrolase
BC342_RS18505	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BC342_RS18515	COG0659	secondary active sulfate transmembrane transporter activity
BC342_RS18635	COG1960	acyl-CoA dehydrogenase activity
BC342_RS18650	COG0318	PFAM AMP-dependent synthetase and ligase
BC342_RS18650	COG1028	Short-chain dehydrogenase reductase Sdr
BC342_RS18650	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BC342_RS18650	COG0300	oxidoreductase activity
BC342_RS18650	COG3321	synthase
BC342_RS18675	COG3320	Male sterility
BC342_RS18675	COG1022	Amp-dependent synthetase and ligase
BC342_RS18680	COG3958	Transketolase
BC342_RS18685	COG3959	Transketolase, thiamine diphosphate binding domain
BC342_RS18710	COG0189	ligase activity
BC342_RS18715	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BC342_RS18720	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BC342_RS18725	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BC342_RS18730	COG1028	Short-chain dehydrogenase reductase Sdr
BC342_RS18735	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BC342_RS18750	COG2267	carboxylic ester hydrolase activity
BC342_RS18790	COG3293	Transposase
BC342_RS18900	COG1205	dead DEAH box helicase
BC342_RS18900	COG1111	helicase
BC342_RS18905	COG1366	Belongs to the anti-sigma-factor antagonist family
BC342_RS18910	COG2172	sigma factor antagonist activity
BC342_RS18915	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
BC342_RS18935	COG1754	DNA topoisomerase type I activity
BC342_RS18935	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BC342_RS18940	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BC342_RS18945	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BC342_RS18960	COG1487	ribonuclease activity
BC342_RS18990	COG0300	oxidoreductase activity
BC342_RS18995	COG1028	Short-chain dehydrogenase reductase Sdr
BC342_RS19000	COG1959	2 iron, 2 sulfur cluster binding
BC342_RS19010	COG0667	Aldo Keto reductase
BC342_RS19015	COG1902	pentaerythritol trinitrate reductase activity
BC342_RS19030	COG4335	DNA alkylation repair
BC342_RS19045	COG3268	Saccharopine dehydrogenase
BC342_RS19055	COG1132	(ABC) transporter
BC342_RS19060	COG1132	(ABC) transporter
BC342_RS19075	COG2192	nodulation
BC342_RS19090	COG2192	nodulation
BC342_RS19095	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BC342_RS19140	COG0367	asparagine synthase
BC342_RS19150	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BC342_RS19155	COG1960	acyl-CoA dehydrogenase activity
BC342_RS19165	COG0277	FAD linked oxidase domain protein
BC342_RS19175	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
BC342_RS19200	COG0515	serine threonine protein kinase
BC342_RS19200	COG2815	serine threonine protein kinase
BC342_RS19205	COG1309	transcriptional regulator
BC342_RS19215	COG4585	Histidine kinase
BC342_RS19220	COG2197	response regulator
BC342_RS19225	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BC342_RS19225	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BC342_RS19245	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BC342_RS19250	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BC342_RS19255	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BC342_RS19260	COG0254	rRNA binding
BC342_RS19270	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BC342_RS19290	COG1012	belongs to the aldehyde dehydrogenase family
BC342_RS19325	COG0076	glutamate decarboxylase activity
BC342_RS19330	COG0789	Transcriptional regulator
BC342_RS19335	COG0393	Putative heavy-metal-binding
BC342_RS19340	COG0586	Pfam SNARE associated Golgi protein
BC342_RS19350	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BC342_RS19355	COG2027	D-alanyl-D-alanine carboxypeptidase
BC342_RS19365	COG0037	tRNA processing
BC342_RS19380	COG0302	gtp cyclohydrolase
BC342_RS19390	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BC342_RS19395	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BC342_RS19435	COG0649	NAD binding
BC342_RS19455	COG1660	Displays ATPase and GTPase activities
BC342_RS19475	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BC342_RS19495	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BC342_RS19515	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BC342_RS19540	COG0739	heme binding
BC342_RS19580	COG2205	protein histidine kinase activity
BC342_RS19585	COG0745	RESPONSE REGULATOR receiver
BC342_RS19595	COG1595	DNA-templated transcription, initiation
BC342_RS19610	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
BC342_RS19630	COG0248	Ppx GppA phosphatase
BC342_RS19635	COG1082	Xylose isomerase domain protein TIM barrel
BC342_RS19645	COG0129	dihydroxy-acid dehydratase activity
BC342_RS19675	COG1129	ABC transporter
BC342_RS19675	COG0842	Transport permease protein
BC342_RS19685	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BC342_RS19690	COG0180	Tryptophanyl-tRNA synthetase
BC342_RS19720	COG2223	nitrite transmembrane transporter activity
BC342_RS19725	COG0123	including yeast histone deacetylase and acetoin utilization protein
BC342_RS19770	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BC342_RS19775	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BC342_RS19780	COG0181	hydroxymethylbilane synthase activity
BC342_RS19785	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BC342_RS19785	COG1648	precorrin-2 dehydrogenase activity
BC342_RS19800	COG3321	synthase
BC342_RS19800	COG0604	alcohol dehydrogenase
BC342_RS19805	COG0113	porphobilinogen synthase activity
BC342_RS19820	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BC342_RS19840	COG0018	arginyl-trna synthetase
BC342_RS19865	COG1690	Belongs to the RtcB family
BC342_RS19875	COG1742	UPF0060 membrane protein
BC342_RS19880	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BC342_RS19885	COG0431	NADPH-dependent FMN reductase
BC342_RS19890	COG0745	RESPONSE REGULATOR receiver
BC342_RS19940	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BC342_RS19985	COG1309	transcriptional regulator
BC342_RS19990	COG1028	Short-chain dehydrogenase reductase Sdr
BC342_RS20005	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
BC342_RS20040	COG1309	transcriptional regulator
BC342_RS20045	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BC342_RS20050	COG0640	Transcriptional regulator
BC342_RS20055	COG0798	PFAM Bile acid sodium symporter
BC342_RS20065	COG1414	Transcriptional regulator
BC342_RS20070	COG0477	Major facilitator Superfamily
BC342_RS20075	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BC342_RS20080	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BC342_RS20090	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BC342_RS20095	COG0406	alpha-ribazole phosphatase activity
BC342_RS20110	COG0785	Cytochrome C biogenesis protein
BC342_RS20115	COG1333	cytochrome c biogenesis protein
BC342_RS20120	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BC342_RS20135	COG0515	serine threonine protein kinase
BC342_RS20135	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BC342_RS20140	COG0583	DNA-binding transcription factor activity
BC342_RS20160	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BC342_RS20165	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BC342_RS20170	COG0163	prenyltransferase activity
BC342_RS20180	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
BC342_RS20195	COG1301	dicarboxylic acid transport
BC342_RS20205	COG1309	transcriptional regulator
BC342_RS20220	COG0183	Belongs to the thiolase family
BC342_RS20230	COG2226	methyltransferase
BC342_RS20235	COG1278	Cold shock
BC342_RS20240	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
BC342_RS20250	COG1674	ftsk spoiiie
BC342_RS20350	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
BC342_RS20495	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
BC342_RS20525	COG2226	methyltransferase
BC342_RS20545	COG0242	peptide deformylase activity
BC342_RS20565	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BC342_RS20570	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BC342_RS20575	COG0649	NAD binding
BC342_RS20585	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BC342_RS20590	COG1034	ATP synthesis coupled electron transport
BC342_RS20595	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BC342_RS20600	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BC342_RS20610	COG0713	ATP synthesis coupled electron transport
BC342_RS20615	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BC342_RS20625	COG1007	ATP synthesis coupled electron transport
BC342_RS20635	COG0514	ATP-dependent DNA helicase (RecQ)
BC342_RS20640	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BC342_RS20645	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BC342_RS20650	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BC342_RS20710	COG0561	phosphatase activity
BC342_RS20720	COG0142	geranyltranstransferase activity
BC342_RS20730	COG1131	(ABC) transporter
BC342_RS20740	COG0655	NAD(P)H dehydrogenase (quinone) activity
BC342_RS20765	COG0702	epimerase
BC342_RS20770	COG1013	pyruvate-flavodoxin oxidoreductase activity
BC342_RS20775	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BC342_RS20775	COG0674	pyruvate-flavodoxin oxidoreductase activity
BC342_RS20795	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BC342_RS20800	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BC342_RS20805	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BC342_RS20810	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BC342_RS20815	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BC342_RS20825	COG0713	ATP synthesis coupled electron transport
BC342_RS20830	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BC342_RS20840	COG1007	ATP synthesis coupled electron transport
BC342_RS20850	COG3304	Inner membrane component domain
BC342_RS20855	COG2261	transglycosylase associated protein
BC342_RS20860	COG1666	GTP binding
BC342_RS20955	COG0702	epimerase
BC342_RS20960	COG0402	S-adenosylhomocysteine deaminase activity
BC342_RS20975	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BC342_RS20980	COG2030	dehydratase
BC342_RS20995	COG0477	Major facilitator Superfamily
BC342_RS21005	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BC342_RS21010	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BC342_RS21015	COG0436	Aminotransferase
BC342_RS21025	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BC342_RS21030	COG0250	Participates in transcription elongation, termination and antitermination
BC342_RS21035	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BC342_RS21040	COG0081	regulation of translation
BC342_RS21055	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BC342_RS21060	COG0222	ribosome binding
BC342_RS21070	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BC342_RS21080	COG0463	Glycosyl transferase, family 2
BC342_RS21085	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BC342_RS21090	COG0049	tRNA binding
BC342_RS21095	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BC342_RS21100	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BC342_RS21130	COG2267	carboxylic ester hydrolase activity
BC342_RS21135	COG1309	transcriptional regulator
BC342_RS21145	COG1028	Short-chain dehydrogenase reductase Sdr
BC342_RS21155	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BC342_RS21180	COG0702	epimerase
BC342_RS21190	COG3209	COG3209 Rhs family protein
BC342_RS21220	COG0051	transcription antitermination factor activity, RNA binding
BC342_RS21225	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BC342_RS21230	COG0088	Forms part of the polypeptide exit tunnel
BC342_RS21235	COG0089	rRNA binding
BC342_RS21240	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BC342_RS21245	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BC342_RS21250	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BC342_RS21255	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BC342_RS21265	COG0255	Belongs to the universal ribosomal protein uL29 family
BC342_RS21270	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BC342_RS21275	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BC342_RS21280	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BC342_RS21285	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BC342_RS21290	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BC342_RS21295	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BC342_RS21300	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BC342_RS21305	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BC342_RS21310	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BC342_RS21315	COG1841	ribosomal large subunit assembly
BC342_RS21320	COG0200	Binds to the 23S rRNA
BC342_RS21325	COG0201	protein transport
BC342_RS21330	COG0563	adenylate kinase activity
BC342_RS21340	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BC342_RS21345	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BC342_RS21350	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BC342_RS21355	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BC342_RS21360	COG0202	RNA polymerase activity
BC342_RS21365	COG0203	ribosomal protein L17
BC342_RS21370	COG0101	tRNA pseudouridine synthase activity
BC342_RS21385	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BC342_RS21390	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BC342_RS21395	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BC342_RS21405	COG1072	(Pantothenic acid kinase))
BC342_RS21415	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BC342_RS21450	COG0736	holo-[acyl-carrier-protein] synthase activity
BC342_RS21455	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BC342_RS21465	COG0802	atpase or kinase
BC342_RS21485	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BC342_RS21530	COG4941	Belongs to the sigma-70 factor family
BC342_RS21540	COG0726	polysaccharide deacetylase
BC342_RS21545	COG0726	polysaccharide deacetylase
BC342_RS21550	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BC342_RS21555	COG0459	protein refolding
BC342_RS21565	COG4221	oxidoreductase activity
BC342_RS21575	COG0583	DNA-binding transcription factor activity
BC342_RS21590	COG1595	DNA-templated transcription, initiation
BC342_RS21600	COG0516	GMP reductase activity
BC342_RS21610	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BC342_RS21620	COG2815	serine threonine protein kinase
BC342_RS21620	COG0515	serine threonine protein kinase
BC342_RS21625	COG0515	serine threonine protein kinase
BC342_RS21630	COG0515	serine threonine protein kinase
BC342_RS21660	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BC342_RS21660	COG0519	Catalyzes the synthesis of GMP from XMP
BC342_RS21700	COG2197	response regulator
BC342_RS21705	COG0791	NLP P60 protein
BC342_RS21730	COG0739	heme binding
BC342_RS21740	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BC342_RS21740	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BC342_RS21755	COG0714	Associated with various cellular activities
BC342_RS21765	COG3552	Protein containing von Willebrand factor type A (VWA) domain
BC342_RS21775	COG0045	succinate-CoA ligase (ADP-forming) activity
BC342_RS21805	COG0138	bifunctional purine biosynthesis protein purh
BC342_RS21825	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BC342_RS21840	COG0039	L-malate dehydrogenase activity
BC342_RS21845	COG1012	belongs to the aldehyde dehydrogenase family
BC342_RS21860	COG4176	ABC-type proline glycine betaine transport system permease component
BC342_RS21870	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BC342_RS21875	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BC342_RS21885	COG0754	glutathionylspermidine amidase activity
BC342_RS21890	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BC342_RS21895	COG0180	Tryptophanyl-tRNA synthetase
BC342_RS21915	COG0671	phosphoesterase, PA-phosphatase related
BC342_RS21935	COG1686	Belongs to the peptidase S11 family
BC342_RS21945	COG1408	metallophosphoesterase
BC342_RS21950	COG0308	aminopeptidase N
BC342_RS21955	COG1309	transcriptional regulator
BC342_RS21985	COG1053	succinate dehydrogenase
BC342_RS21995	COG2009	succinate dehydrogenase
BC342_RS22025	COG1595	DNA-templated transcription, initiation
BC342_RS22040	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BC342_RS22040	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BC342_RS22065	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BC342_RS22090	COG1216	Glycosyl transferase, family 2
BC342_RS22105	COG2089	acid synthase
BC342_RS22115	COG1473	amidohydrolase
BC342_RS22115	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
BC342_RS22120	COG1744	ABC transporter substrate-binding protein PnrA-like
BC342_RS22125	COG1744	ABC transporter substrate-binding protein PnrA-like
BC342_RS22130	COG3845	ABC transporter
BC342_RS22140	COG1079	Belongs to the binding-protein-dependent transport system permease family
BC342_RS22170	COG4948	Mandelate Racemase Muconate Lactonizing
BC342_RS22200	COG2814	Major facilitator Superfamily
BC342_RS22205	COG0583	DNA-binding transcription factor activity
BC342_RS22225	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BC342_RS22245	COG0745	RESPONSE REGULATOR receiver
BC342_RS22250	COG1595	DNA-templated transcription, initiation
BC342_RS22265	COG0515	serine threonine protein kinase
BC342_RS22270	COG1012	belongs to the aldehyde dehydrogenase family
BC342_RS22275	COG1012	belongs to the aldehyde dehydrogenase family
BC342_RS22290	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BC342_RS22315	COG4770	biotin carboxylase activity
BC342_RS22325	COG0424	maF-like protein
BC342_RS22335	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BC342_RS22345	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
BC342_RS22355	COG1024	Enoyl-CoA hydratase
BC342_RS22385	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BC342_RS22400	COG1064	alcohol dehydrogenase
BC342_RS22405	COG0667	Aldo Keto reductase
BC342_RS22425	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BC342_RS22450	COG2255	four-way junction helicase activity
BC342_RS22455	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BC342_RS22470	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BC342_RS22480	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BC342_RS22495	COG1331	Highly conserved protein containing a thioredoxin domain
BC342_RS22510	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
BC342_RS22520	COG0436	Aminotransferase
BC342_RS22525	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
BC342_RS22540	COG1414	Transcriptional regulator
BC342_RS22545	COG0251	oxidation-reduction process
BC342_RS22550	COG2610	gluconate transmembrane transporter activity
BC342_RS22610	COG2894	cell division
BC342_RS22705	COG2226	methyltransferase
BC342_RS22710	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BC342_RS22725	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BC342_RS22730	COG0450	alkyl hydroperoxide reductase
BC342_RS22745	COG1136	(ABC) transporter
BC342_RS22765	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BC342_RS22780	COG0114	fumarate hydratase activity
BC342_RS22785	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
BC342_RS22785	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
BC342_RS22810	COG0778	Nitroreductase
BC342_RS22815	COG1722	exodeoxyribonuclease VII activity
BC342_RS22820	COG1570	exodeoxyribonuclease VII activity
BC342_RS22830	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BC342_RS22845	COG0012	GTP binding
BC342_RS22855	COG1733	regulation of RNA biosynthetic process
BC342_RS22965	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BC342_RS22970	COG4166	transmembrane transport
BC342_RS22980	COG0444	Belongs to the ABC transporter superfamily
BC342_RS22985	COG4608	Belongs to the ABC transporter superfamily
BC342_RS22990	COG1960	acyl-CoA dehydrogenase activity
BC342_RS22995	COG2207	Transcriptional regulator
BC342_RS23005	COG0601	transmembrane transport
BC342_RS23010	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BC342_RS23015	COG0444	Belongs to the ABC transporter superfamily
BC342_RS23075	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BC342_RS23120	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BC342_RS23130	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BC342_RS23140	COG0519	Catalyzes the synthesis of GMP from XMP
BC342_RS23145	COG1024	Enoyl-CoA hydratase
BC342_RS23160	COG1595	DNA-templated transcription, initiation
BC342_RS23170	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BC342_RS23175	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BC342_RS23210	COG0598	Magnesium transport protein CorA
BC342_RS23220	COG2814	Major facilitator Superfamily
BC342_RS23235	COG2095	MarC family integral membrane protein
BC342_RS23240	COG1432	Conserved Protein
BC342_RS23250	COG0513	Belongs to the DEAD box helicase family
BC342_RS23315	COG0596	Alpha beta hydrolase
BC342_RS23335	COG0210	DNA helicase
BC342_RS23350	COG2816	NAD+ diphosphatase activity
BC342_RS23375	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BC342_RS23425	COG3480	Lon protease (S16) C-terminal proteolytic domain
BC342_RS23435	COG1615	UPF0182 protein
BC342_RS23460	COG0753	catalase activity
BC342_RS23470	COG0318	PFAM AMP-dependent synthetase and ligase
BC342_RS23475	COG1024	Enoyl-CoA hydratase
BC342_RS23485	COG1024	Enoyl-CoA hydratase
BC342_RS23490	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BC342_RS23500	COG2271	Major facilitator Superfamily
BC342_RS23505	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BC342_RS23515	COG0183	Belongs to the thiolase family
BC342_RS23520	COG0583	DNA-binding transcription factor activity
BC342_RS23530	COG0483	inositol monophosphate 1-phosphatase activity
BC342_RS23540	COG2076	Multidrug Resistance protein
BC342_RS23545	COG1162	GTPase activity
BC342_RS23550	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BC342_RS23560	COG2135	peptidase activity
BC342_RS23570	COG1595	DNA-templated transcription, initiation
BC342_RS23575	COG5662	AntiSigma factor
BC342_RS23595	COG0242	peptide deformylase activity
BC342_RS23605	COG2124	cytochrome p450
BC342_RS23640	COG2188	Transcriptional regulator
BC342_RS23645	COG2182	Extracellular solute-binding protein
BC342_RS23650	COG1175	transmembrane transport
BC342_RS23655	COG0395	ABC-type sugar transport system, permease component
BC342_RS23660	COG1472	Belongs to the glycosyl hydrolase 3 family
BC342_RS23665	COG0363	glucosamine-6-phosphate deaminase activity
BC342_RS23680	COG1597	lipid kinase activity
BC342_RS23710	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BC342_RS23720	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BC342_RS23725	COG0142	geranyltranstransferase activity
BC342_RS23740	COG3842	ATPase activity
BC342_RS23765	COG4106	trans-aconitate 2-methyltransferase activity
BC342_RS23770	COG1126	abc transporter atp-binding protein
BC342_RS23785	COG0281	malic enzyme
BC342_RS23790	COG0604	alcohol dehydrogenase
BC342_RS23855	COG0567	Dehydrogenase, E1 component
BC342_RS23855	COG0508	dehydrogenase complex catalyzes the overall conversion of
BC342_RS23860	COG2205	protein histidine kinase activity
BC342_RS23865	COG0745	RESPONSE REGULATOR receiver
BC342_RS23875	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BC342_RS23920	COG0791	NLP P60 protein
BC342_RS23920	COG3883	PFAM NLP P60 protein
BC342_RS23960	COG2205	protein histidine kinase activity
BC342_RS23980	COG1793	dna ligase
BC342_RS23980	COG3285	dna ligase
BC342_RS23985	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BC342_RS24000	COG3467	pyridoxamine 5'-phosphate
BC342_RS24015	COG2867	negative regulation of translational initiation
BC342_RS24020	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BC342_RS24025	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BC342_RS24030	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BC342_RS24035	COG0662	Cupin 2, conserved barrel domain protein
BC342_RS24055	COG2079	MmgE PrpD family protein
BC342_RS24060	COG1960	acyl-CoA dehydrogenase activity
BC342_RS24065	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BC342_RS24075	COG2186	Transcriptional regulator
BC342_RS24080	COG2814	Major facilitator Superfamily
BC342_RS24080	COG0477	Major facilitator Superfamily
BC342_RS24135	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
BC342_RS24150	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BC342_RS24155	COG2801	Transposase and inactivated derivatives
BC342_RS24155	COG3415	Transposase
BC342_RS24160	COG2188	Transcriptional regulator
BC342_RS24210	COG0745	RESPONSE REGULATOR receiver
BC342_RS24225	COG0018	arginyl-trna synthetase
BC342_RS24230	COG0019	diaminopimelate decarboxylase activity
BC342_RS24235	COG0460	homoserine dehydrogenase
BC342_RS24240	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BC342_RS24245	COG0083	homoserine kinase activity
BC342_RS24255	COG1316	TRANSCRIPTIONal
BC342_RS24260	COG0254	rRNA binding
BC342_RS24265	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BC342_RS24270	COG2890	protein-(glutamine-N5) methyltransferase activity
BC342_RS24280	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BC342_RS24285	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BC342_RS24290	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BC342_RS24305	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BC342_RS24310	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BC342_RS24315	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BC342_RS24320	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BC342_RS24325	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BC342_RS24330	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BC342_RS24335	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BC342_RS24350	COG2197	response regulator
BC342_RS24355	COG4585	Histidine kinase
BC342_RS24375	COG1250	3-hydroxyacyl-CoA dehydrogenase
BC342_RS24390	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
BC342_RS24425	COG1131	(ABC) transporter
BC342_RS24445	COG0183	Belongs to the thiolase family
BC342_RS24460	COG0745	RESPONSE REGULATOR receiver
BC342_RS24465	COG2205	protein histidine kinase activity
BC342_RS24510	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BC342_RS24510	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BC342_RS24555	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BC342_RS24560	COG0280	phosphate acetyltransferase
BC342_RS24560	COG0857	belongs to the CobB CobQ family
BC342_RS24565	COG0205	6-phosphofructokinase activity
BC342_RS24575	COG0395	ABC-type sugar transport system, permease component
BC342_RS24585	COG1653	transport
BC342_RS24590	COG4565	transcriptional regulatory protein
BC342_RS24595	COG3290	protein histidine kinase activity
BC342_RS24600	COG1301	dicarboxylic acid transport
BC342_RS24620	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BC342_RS24625	COG3281	Trehalose synthase
BC342_RS24630	COG0366	Alpha amylase catalytic
BC342_RS24640	COG0058	SHG alpha-glucan phosphorylase activity
BC342_RS24655	COG1132	(ABC) transporter
BC342_RS24665	COG1132	(ABC) transporter
BC342_RS24670	COG1132	(ABC) transporter
BC342_RS24685	COG1376	ErfK ybiS ycfS ynhG family protein
BC342_RS24715	COG0477	Major facilitator Superfamily
BC342_RS24720	COG2197	response regulator
BC342_RS24725	COG4585	Histidine kinase
BC342_RS24735	COG1760	l-serine dehydratase
BC342_RS24740	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BC342_RS24745	COG0509	glycine decarboxylation via glycine cleavage system
BC342_RS24750	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BC342_RS24775	COG4166	transmembrane transport
BC342_RS24785	COG0444	Belongs to the ABC transporter superfamily
BC342_RS24790	COG4608	Belongs to the ABC transporter superfamily
BC342_RS24795	COG2860	membrane
BC342_RS24810	COG1136	(ABC) transporter
BC342_RS24810	COG0577	efflux transmembrane transporter activity
BC342_RS24835	COG2860	membrane
BC342_RS24845	COG0789	Transcriptional regulator
BC342_RS24855	COG1309	transcriptional regulator
BC342_RS24875	COG0482	sulfurtransferase activity
BC342_RS24885	COG1611	Belongs to the LOG family
BC342_RS24890	COG4221	oxidoreductase activity
BC342_RS24900	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BC342_RS24910	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BC342_RS24915	COG0154	amidase activity
BC342_RS24925	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BC342_RS24930	COG2409	Drug exporters of the RND superfamily
BC342_RS24945	COG2197	response regulator
BC342_RS24960	COG2133	pyrroloquinoline quinone binding
BC342_RS24965	COG0667	Aldo Keto reductase
BC342_RS24975	COG5001	Diguanylate cyclase
BC342_RS24985	COG0440	acetolactate synthase activity
BC342_RS24990	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BC342_RS25000	COG0477	Major facilitator Superfamily
BC342_RS25015	COG0506	proline dehydrogenase activity
BC342_RS25020	COG1012	belongs to the aldehyde dehydrogenase family
BC342_RS25025	COG0473	3-isopropylmalate dehydrogenase activity
BC342_RS25030	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BC342_RS25035	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BC342_RS25060	COG5492	domain, Protein
BC342_RS25065	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BC342_RS25085	COG2018	Roadblock/LC7 domain
BC342_RS25105	COG2018	Roadblock/LC7 domain
BC342_RS25110	COG5002	protein histidine kinase activity
BC342_RS25120	COG0179	Fumarylacetoacetate (FAA) hydrolase
BC342_RS25125	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BC342_RS25135	COG4977	sequence-specific DNA binding
BC342_RS25135	COG1917	Cupin 2, conserved barrel domain protein
BC342_RS25170	COG1414	Transcriptional regulator
BC342_RS25175	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BC342_RS25180	COG0066	3-isopropylmalate dehydratase activity
BC342_RS25190	COG0776	regulation of translation
BC342_RS25200	COG1920	GTP binding
BC342_RS25210	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BC342_RS25215	COG1181	Belongs to the D-alanine--D-alanine ligase family
BC342_RS25230	COG0351	phosphomethylpyrimidine kinase
BC342_RS25240	COG1461	Dihydroxyacetone kinase
BC342_RS25250	COG0742	ribosomal rna small subunit methyltransferase
BC342_RS25255	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BC342_RS25270	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BC342_RS25275	COG0571	ribonuclease III activity
BC342_RS25280	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BC342_RS25285	COG1733	regulation of RNA biosynthetic process
BC342_RS25295	COG1028	Short-chain dehydrogenase reductase Sdr
BC342_RS25330	COG2340	Cysteine-rich secretory protein family
BC342_RS25335	COG1254	Belongs to the acylphosphatase family
BC342_RS25350	COG0477	Major facilitator Superfamily
BC342_RS25355	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BC342_RS25365	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BC342_RS25380	COG0596	Alpha beta hydrolase
BC342_RS25385	COG0318	PFAM AMP-dependent synthetase and ligase
BC342_RS25410	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BC342_RS25445	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BC342_RS25470	COG0228	four-way junction DNA binding
BC342_RS25475	COG1837	Belongs to the UPF0109 family
BC342_RS25480	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BC342_RS25485	COG0336	Belongs to the RNA methyltransferase TrmD family
BC342_RS25490	COG0335	large ribosomal subunit rRNA binding
BC342_RS25495	COG0681	Belongs to the peptidase S26 family
BC342_RS25500	COG0681	Belongs to the peptidase S26 family
BC342_RS25520	COG0792	nuclease activity
BC342_RS25560	COG1191	sigma factor activity
BC342_RS25580	COG0052	Belongs to the universal ribosomal protein uS2 family
BC342_RS25585	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BC342_RS25590	COG0528	UMP kinase activity
BC342_RS25595	COG0233	cytoplasmic translational termination
BC342_RS25600	COG0575	Belongs to the CDS family
BC342_RS25605	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BC342_RS25615	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BC342_RS25620	COG3842	ATPase activity
BC342_RS25650	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BC342_RS25660	COG1012	belongs to the aldehyde dehydrogenase family
BC342_RS25665	COG0584	glycerophosphoryl diester phosphodiesterase
BC342_RS25670	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BC342_RS25700	COG3842	ATPase activity
BC342_RS25710	COG1177	transmembrane transport
BC342_RS25715	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BC342_RS25750	COG1012	belongs to the aldehyde dehydrogenase family
BC342_RS25770	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BC342_RS25775	COG0750	zinc metalloprotease
BC342_RS25780	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BC342_RS25795	COG0442	prolyl-tRNA aminoacylation
BC342_RS25815	COG0779	Required for maturation of 30S ribosomal subunits
BC342_RS25825	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BC342_RS25835	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BC342_RS25840	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BC342_RS25855	COG4608	Belongs to the ABC transporter superfamily
BC342_RS25870	COG0601	transmembrane transport
BC342_RS25875	COG0747	negative chemotaxis
BC342_RS25880	COG0455	bacterial-type flagellum organization
BC342_RS25890	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BC342_RS25895	COG1185	polyribonucleotide nucleotidyltransferase activity
BC342_RS25900	COG0612	Peptidase, M16
BC342_RS25905	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BC342_RS25925	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
BC342_RS25930	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BC342_RS25935	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BC342_RS25965	COG2208	phosphoserine phosphatase activity
BC342_RS25965	COG2770	Histidine kinase
BC342_RS25980	COG1674	ftsk spoiiie
BC342_RS25990	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BC342_RS26000	COG1058	Belongs to the CinA family
BC342_RS26000	COG1546	Belongs to the CinA family
BC342_RS26005	COG1396	sequence-specific DNA binding
BC342_RS26015	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BC342_RS26020	COG1201	RNA secondary structure unwinding
BC342_RS26025	COG1917	Cupin 2, conserved barrel domain protein
BC342_RS26025	COG2207	Transcriptional regulator
BC342_RS26065	COG0246	Mannitol dehydrogenase
BC342_RS26070	COG0477	Major facilitator Superfamily
BC342_RS26075	COG1063	alcohol dehydrogenase
BC342_RS26085	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BC342_RS26095	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BC342_RS26110	COG0765	amino acid transport
BC342_RS26115	COG0765	amino acid transport
BC342_RS26120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BC342_RS26125	COG1126	abc transporter atp-binding protein
BC342_RS26130	COG0745	RESPONSE REGULATOR receiver
BC342_RS26135	COG2205	protein histidine kinase activity
BC342_RS26155	COG3851	Histidine kinase
BC342_RS26160	COG2197	response regulator
BC342_RS26185	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BC342_RS26195	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BC342_RS26200	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BC342_RS26210	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BC342_RS26245	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BC342_RS26250	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BC342_RS26255	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BC342_RS26270	COG0588	phosphoglycerate mutase activity
BC342_RS26290	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BC342_RS26325	COG2186	Transcriptional regulator
BC342_RS26330	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BC342_RS26345	COG0187	DNA topoisomerase II activity
BC342_RS26360	COG2197	response regulator
BC342_RS26370	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BC342_RS26375	COG4565	transcriptional regulatory protein
BC342_RS26380	COG3290	protein histidine kinase activity
BC342_RS26395	COG2249	NAD(P)H dehydrogenase (quinone) activity
BC342_RS26400	COG0583	DNA-binding transcription factor activity
BC342_RS26420	COG0454	-acetyltransferase
BC342_RS26420	COG0456	acetyltransferase
BC342_RS26425	COG1028	Short-chain dehydrogenase reductase Sdr
BC342_RS26455	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BC342_RS26460	COG0612	Peptidase, M16
BC342_RS26475	COG1802	Transcriptional regulator
BC342_RS26480	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BC342_RS26500	COG1435	thymidine kinase activity
BC342_RS26535	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BC342_RS26545	COG0745	RESPONSE REGULATOR receiver
BC342_RS26550	COG2205	protein histidine kinase activity
BC342_RS26610	COG0569	domain protein
BC342_RS26615	COG0531	amino acid
BC342_RS26620	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BC342_RS26630	COG2197	response regulator
BC342_RS26670	COG2814	Major facilitator Superfamily
BC342_RS26690	COG1028	Short-chain dehydrogenase reductase Sdr
BC342_RS26700	COG2508	Transcriptional regulator
BC342_RS26710	COG0318	PFAM AMP-dependent synthetase and ligase
BC342_RS26745	COG4948	Mandelate Racemase Muconate Lactonizing
BC342_RS26750	COG0395	ABC-type sugar transport system, permease component
BC342_RS26765	COG2188	Transcriptional regulator
BC342_RS26770	COG0477	Major facilitator Superfamily
BC342_RS26795	COG1609	Transcriptional regulator
BC342_RS26815	COG1175	transmembrane transport
BC342_RS26820	COG0395	ABC-type sugar transport system, permease component
BC342_RS26850	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BC342_RS26865	COG1063	alcohol dehydrogenase
BC342_RS26920	COG0662	Cupin 2, conserved barrel domain protein
BC342_RS26930	COG0583	DNA-binding transcription factor activity
BC342_RS26945	COG2197	response regulator
BC342_RS26950	COG4585	Histidine kinase
BC342_RS26960	COG0531	amino acid
BC342_RS26970	COG0477	Major facilitator Superfamily
BC342_RS26975	COG1122	ATPase activity
BC342_RS26985	COG1930	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
BC342_RS26990	COG0310	cobalt ion transport
BC342_RS26995	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BC342_RS27010	COG1799	cell septum assembly
BC342_RS27035	COG0475	glutathione-regulated potassium exporter activity
BC342_RS27040	COG2235	arginine
BC342_RS27045	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BC342_RS27050	COG0531	amino acid
BC342_RS27060	COG1024	Enoyl-CoA hydratase
BC342_RS27140	COG2124	cytochrome p450
BC342_RS27150	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BC342_RS27175	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BC342_RS27180	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BC342_RS27190	COG1414	Transcriptional regulator
BC342_RS27195	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BC342_RS27205	COG2130	NADP-dependent
BC342_RS27210	COG1233	COG1233 Phytoene dehydrogenase and related
BC342_RS27240	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BC342_RS27245	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BC342_RS27270	COG1653	transport
BC342_RS27275	COG1175	transmembrane transport
BC342_RS27280	COG0395	ABC-type sugar transport system, permease component
BC342_RS27285	COG1940	carbohydrate kinase activity
BC342_RS27290	COG4213	ABC transporter substrate-binding protein
BC342_RS27300	COG4214	carbohydrate transport
BC342_RS27305	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BC342_RS27310	COG0531	amino acid
BC342_RS27330	COG0183	Belongs to the thiolase family
BC342_RS27350	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BC342_RS27355	COG1472	Belongs to the glycosyl hydrolase 3 family
BC342_RS27435	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BC342_RS27440	COG3253	May function as heme-dependent peroxidase
BC342_RS27455	COG3220	belongs to the UPF0276 family
BC342_RS27465	COG3842	ATPase activity
BC342_RS27480	COG1028	Short-chain dehydrogenase reductase Sdr
BC342_RS27480	COG3321	synthase
BC342_RS27480	COG0604	alcohol dehydrogenase
BC342_RS27485	COG1733	regulation of RNA biosynthetic process
BC342_RS27490	COG0726	polysaccharide deacetylase
BC342_RS27495	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BC342_RS27495	COG0723	plastoquinol--plastocyanin reductase activity
BC342_RS27505	COG0659	secondary active sulfate transmembrane transporter activity
BC342_RS27535	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BC342_RS27540	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BC342_RS27565	COG3629	intracellular signal transduction
BC342_RS27565	COG3903	Transcriptional regulator
BC342_RS27570	COG2205	protein histidine kinase activity
BC342_RS27575	COG0745	RESPONSE REGULATOR receiver
BC342_RS27600	COG1174	glycine betaine transport
BC342_RS27605	COG1174	glycine betaine transport
BC342_RS27655	COG1309	transcriptional regulator
BC342_RS27680	COG3173	Aminoglycoside phosphotransferase
BC342_RS27725	COG1175	transmembrane transport
BC342_RS27740	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BC342_RS27760	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BC342_RS27765	COG1116	anion transmembrane transporter activity
BC342_RS27785	COG0529	Catalyzes the synthesis of activated sulfate
BC342_RS27790	COG0175	sulfate reduction
BC342_RS27820	COG1960	acyl-CoA dehydrogenase activity
BC342_RS27855	COG1846	Transcriptional regulator
BC342_RS27855	COG1940	carbohydrate kinase activity
BC342_RS27905	COG2027	D-alanyl-D-alanine carboxypeptidase
BC342_RS27920	COG0714	Associated with various cellular activities
BC342_RS27935	COG2040	homocysteine
BC342_RS27950	COG2197	response regulator
BC342_RS27960	COG0277	FAD linked oxidase domain protein
BC342_RS27975	COG1162	GTPase activity
BC342_RS27980	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BC342_RS28025	COG1802	Transcriptional regulator
BC342_RS28030	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BC342_RS28040	COG2197	response regulator
BC342_RS28075	COG3835	regulator
BC342_RS28090	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BC342_RS28095	COG2252	PERMEase
BC342_RS28115	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BC342_RS28130	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BC342_RS28135	COG0859	PFAM glycosyl transferase family 9
BC342_RS28140	COG0438	transferase activity, transferring glycosyl groups
BC342_RS28145	COG0438	transferase activity, transferring glycosyl groups
BC342_RS28150	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BC342_RS28190	COG2319	Wd-40 repeat
BC342_RS28190	COG4249	Peptidase C14 caspase catalytic subunit p20
BC342_RS28245	COG2197	response regulator
BC342_RS28250	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BC342_RS28255	COG0318	PFAM AMP-dependent synthetase and ligase
BC342_RS28290	COG3960	tartronate-semialdehyde synthase activity
BC342_RS28305	COG2084	Dehydrogenase
BC342_RS28310	COG3622	Belongs to the hyi family
BC342_RS28330	COG2351	hydroxyisourate hydrolase activity
BC342_RS28345	COG2233	PERMEase
BC342_RS28355	COG0406	alpha-ribazole phosphatase activity
BC342_RS28360	COG0436	Aminotransferase
BC342_RS28380	COG4264	IucA IucC family
BC342_RS28400	COG1285	pathogenesis
BC342_RS28410	COG3046	protein related to deoxyribodipyrimidine photolyase
BC342_RS28415	COG3293	Transposase
BC342_RS28430	COG2813	Specifically methylates the guanine in position
BC342_RS28470	COG1414	Transcriptional regulator
BC342_RS28475	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BC342_RS28480	COG4266	Belongs to the allantoicase family
BC342_RS28485	COG2066	Belongs to the glutaminase family
BC342_RS28500	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BC342_RS28515	COG1335	isochorismatase
BC342_RS28525	COG2188	Transcriptional regulator
BC342_RS28545	COG1940	carbohydrate kinase activity
BC342_RS28555	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BC342_RS28565	COG2197	response regulator
BC342_RS28600	COG0444	Belongs to the ABC transporter superfamily
BC342_RS28605	COG4608	Belongs to the ABC transporter superfamily
BC342_RS28625	COG0523	cobalamin synthesis protein
BC342_RS28700	COG3433	isochorismatase activity
BC342_RS28700	COG1535	isochorismatase
BC342_RS28715	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BC342_RS28720	COG1120	ATPase activity
BC342_RS28725	COG0596	Alpha beta hydrolase
BC342_RS28740	COG1733	regulation of RNA biosynthetic process
BC342_RS28765	COG1414	Transcriptional regulator
BC342_RS28770	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BC342_RS28775	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BC342_RS28780	COG1414	Transcriptional regulator
BC342_RS28785	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BC342_RS28795	COG1309	transcriptional regulator
BC342_RS28820	COG0596	Alpha beta hydrolase
BC342_RS28840	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BC342_RS28860	COG0673	inositol 2-dehydrogenase activity
BC342_RS28870	COG0405	Gamma-glutamyltransferase
BC342_RS28890	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BC342_RS28900	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BC342_RS28905	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BC342_RS28910	COG1953	Uracil, thiamine, allantoin
BC342_RS29000	COG0596	Alpha beta hydrolase
BC342_RS29005	COG2175	clavaminate synthase activity
BC342_RS29010	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BC342_RS29025	COG0179	Fumarylacetoacetate (FAA) hydrolase
BC342_RS29030	COG2124	cytochrome p450
BC342_RS29040	COG2124	cytochrome p450
BC342_RS29055	COG1960	acyl-CoA dehydrogenase activity
BC342_RS29060	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BC342_RS29070	COG0142	geranyltranstransferase activity
BC342_RS29075	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BC342_RS29085	COG1028	Short-chain dehydrogenase reductase Sdr
BC342_RS29110	COG1819	glycosyl
BC342_RS29130	COG2226	methyltransferase
BC342_RS29145	COG0483	inositol monophosphate 1-phosphatase activity
BC342_RS29155	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
BC342_RS29190	COG0477	Major facilitator Superfamily
BC342_RS29200	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BC342_RS29210	COG0583	DNA-binding transcription factor activity
BC342_RS29215	COG2610	gluconate transmembrane transporter activity
BC342_RS29225	COG3540	Alkaline phosphatase
BC342_RS29235	COG0640	Transcriptional regulator
BC342_RS29250	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BC342_RS29260	COG1929	Belongs to the glycerate kinase type-1 family
BC342_RS29270	COG0688	phosphatidylethanolamine metabolic process
BC342_RS29275	COG1960	acyl-CoA dehydrogenase activity
BC342_RS29285	COG2301	Belongs to the HpcH HpaI aldolase family
BC342_RS29290	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BC342_RS29290	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BC342_RS29345	COG2208	phosphoserine phosphatase activity
BC342_RS29345	COG1366	Belongs to the anti-sigma-factor antagonist family
BC342_RS29345	COG2172	sigma factor antagonist activity
BC342_RS29355	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BC342_RS29360	COG2362	D-Aminopeptidase
BC342_RS29365	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BC342_RS29375	COG1619	proteins homologs of microcin C7 resistance protein MccF
BC342_RS29400	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BC342_RS29470	COG2226	methyltransferase
BC342_RS29475	COG1597	lipid kinase activity
BC342_RS29505	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BC342_RS29575	COG2154	pterin-4-alpha-carbinolamine dehydratase
BC342_RS29580	COG4106	trans-aconitate 2-methyltransferase activity
BC342_RS29580	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BC342_RS29585	COG5297	Belongs to the glycosyl hydrolase family 6
BC342_RS29590	COG2226	methyltransferase
BC342_RS29595	COG0656	L-ascorbic acid biosynthetic process
BC342_RS29615	COG2801	Transposase and inactivated derivatives
BC342_RS29615	COG3415	Transposase
BC342_RS29630	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BC342_RS29640	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BC342_RS29645	COG3383	formate dehydrogenase (NAD+) activity
BC342_RS29650	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BC342_RS29660	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BC342_RS29675	COG1129	ABC transporter
BC342_RS29680	COG1172	Belongs to the binding-protein-dependent transport system permease family
BC342_RS29705	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BC342_RS29740	COG2223	nitrite transmembrane transporter activity
BC342_RS29750	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BC342_RS29760	COG0045	succinate-CoA ligase (ADP-forming) activity
BC342_RS29770	COG1012	belongs to the aldehyde dehydrogenase family
BC342_RS29805	COG2182	Extracellular solute-binding protein
BC342_RS29810	COG1175	transmembrane transport
BC342_RS29815	COG0395	ABC-type sugar transport system, permease component
BC342_RS29845	COG1733	regulation of RNA biosynthetic process
BC342_RS29865	COG0446	pyridine nucleotide-disulphide oxidoreductase
BC342_RS29865	COG1902	pentaerythritol trinitrate reductase activity
BC342_RS29870	COG0300	oxidoreductase activity
BC342_RS29885	COG0765	amino acid transport
BC342_RS29890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BC342_RS29905	COG1028	Short-chain dehydrogenase reductase Sdr
BC342_RS29925	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BC342_RS29970	COG0300	oxidoreductase activity
BC342_RS29995	COG0297	glycogen (starch) synthase activity
BC342_RS30015	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BC342_RS30025	COG0477	Major facilitator Superfamily
BC342_RS30035	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BC342_RS30040	COG3185	4-Hydroxyphenylpyruvate dioxygenase
BC342_RS30040	COG1082	Xylose isomerase domain protein TIM barrel
BC342_RS30050	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BC342_RS30055	COG0166	Belongs to the GPI family
BC342_RS30070	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BC342_RS30090	COG1486	melibiose metabolic process
BC342_RS30100	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BC342_RS30145	COG3938	Belongs to the proline racemase family
BC342_RS30170	COG3511	phospholipase C
BC342_RS30200	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BC342_RS30205	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BC342_RS30210	COG3485	protocatechuate 3,4-dioxygenase
BC342_RS30215	COG3485	protocatechuate 3,4-dioxygenase
BC342_RS30225	COG1470	cell adhesion involved in biofilm formation
BC342_RS30235	COG1793	dna ligase
BC342_RS30265	COG0656	L-ascorbic acid biosynthetic process
BC342_RS30290	COG0488	(ABC) transporter
BC342_RS30310	COG1515	deoxyribonuclease V activity
BC342_RS30325	COG3268	Saccharopine dehydrogenase
BC342_RS30330	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BC342_RS30335	COG0183	Belongs to the thiolase family
BC342_RS30340	COG1024	Enoyl-CoA hydratase
BC342_RS30340	COG1250	3-hydroxyacyl-CoA dehydrogenase
BC342_RS30350	COG1113	amino acid transport
BC342_RS30370	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BC342_RS30380	COG0488	(ABC) transporter
BC342_RS30385	COG2183	response to ionizing radiation
BC342_RS30415	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
BC342_RS30455	COG1134	teichoic acid transport
BC342_RS30460	COG1562	ergosterol biosynthetic process
BC342_RS30470	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BC342_RS30495	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BC342_RS30500	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BC342_RS30520	COG2365	Tyrosine phosphatase family
BC342_RS30560	COG1408	metallophosphoesterase
BC342_RS30580	COG0601	transmembrane transport
BC342_RS30595	COG1021	2,3-dihydroxybenzoate-AMP ligase
BC342_RS30600	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
BC342_RS30600	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BC342_RS30605	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BC342_RS30605	COG2226	methyltransferase
BC342_RS30605	COG3433	isochorismatase activity
BC342_RS30635	COG1132	(ABC) transporter
BC342_RS30635	COG2375	cellular response to nickel ion
BC342_RS30640	COG1132	(ABC) transporter
BC342_RS30645	COG1169	isochorismate synthase
BC342_RS30655	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BC342_RS30660	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BC342_RS30695	COG1063	alcohol dehydrogenase
BC342_RS30700	COG0156	8-amino-7-oxononanoate synthase activity
BC342_RS30705	COG0583	DNA-binding transcription factor activity
BC342_RS30730	COG0604	alcohol dehydrogenase
BC342_RS30735	COG2111	Na H antiporter
BC342_RS30735	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BC342_RS30740	COG1006	Multisubunit Na H antiporter MnhC subunit
BC342_RS30745	COG0651	ATP synthesis coupled electron transport
BC342_RS30760	COG1320	monovalent cation:proton antiporter activity
BC342_RS30800	COG2267	carboxylic ester hydrolase activity
BC342_RS30805	COG0183	Belongs to the thiolase family
BC342_RS30810	COG0318	PFAM AMP-dependent synthetase and ligase
BC342_RS30835	COG0745	RESPONSE REGULATOR receiver
BC342_RS30840	COG2205	protein histidine kinase activity
BC342_RS30845	COG2986	histidine ammonia-lyase
BC342_RS30870	COG0475	glutathione-regulated potassium exporter activity
BC342_RS30875	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BC342_RS30890	COG1028	Short-chain dehydrogenase reductase Sdr
BC342_RS30895	COG1021	2,3-dihydroxybenzoate-AMP ligase
BC342_RS30900	COG3433	isochorismatase activity
BC342_RS30900	COG1535	isochorismatase
BC342_RS30905	COG3486	L-lysine 6-monooxygenase (NADPH) activity
BC342_RS30920	COG3433	isochorismatase activity
BC342_RS30920	COG1535	isochorismatase
BC342_RS30935	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BC342_RS30940	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BC342_RS30945	COG1120	ATPase activity
BC342_RS30960	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BC342_RS30980	COG2188	Transcriptional regulator
BC342_RS30985	COG3962	Belongs to the TPP enzyme family
BC342_RS30990	COG3718	enzyme involved in inositol metabolism
BC342_RS31000	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BC342_RS31030	COG0673	inositol 2-dehydrogenase activity
BC342_RS31035	COG0673	inositol 2-dehydrogenase activity
BC342_RS31040	COG2186	Transcriptional regulator
BC342_RS31045	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BC342_RS31050	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BC342_RS31070	COG0385	Bile acid
BC342_RS31090	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BC342_RS31095	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BC342_RS31110	COG0546	phosphoglycolate phosphatase activity
BC342_RS31120	COG0604	alcohol dehydrogenase
BC342_RS31120	COG3321	synthase
BC342_RS31140	COG0604	alcohol dehydrogenase
BC342_RS31140	COG3321	synthase
BC342_RS31150	COG2162	N-hydroxyarylamine O-acetyltransferase activity
BC342_RS31190	COG0778	Nitroreductase
BC342_RS31205	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BC342_RS31210	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BC342_RS31215	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BC342_RS31230	COG2197	response regulator
BC342_RS31240	COG1404	Belongs to the peptidase S8 family
BC342_RS31255	COG2124	cytochrome p450
BC342_RS31265	COG2838	Isocitrate dehydrogenase
BC342_RS31270	COG0668	transmembrane transport
BC342_RS31285	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BC342_RS31305	COG1132	(ABC) transporter
BC342_RS31310	COG0366	Alpha amylase catalytic
BC342_RS31315	COG0395	ABC-type sugar transport system, permease component
BC342_RS31320	COG1175	transmembrane transport
BC342_RS31325	COG1653	transport
BC342_RS31360	COG2376	Dihydroxyacetone kinase
BC342_RS31365	COG2376	Dihydroxyacetone kinase
BC342_RS31370	COG0477	Major facilitator Superfamily
BC342_RS31375	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BC342_RS31395	COG2031	fatty acid transporter
BC342_RS31400	COG2423	ornithine cyclodeaminase activity
BC342_RS31410	COG1802	Transcriptional regulator
BC342_RS31470	COG0667	Aldo Keto reductase
BC342_RS31475	COG0583	DNA-binding transcription factor activity
BC342_RS31490	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BC342_RS31500	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BC342_RS31505	COG1309	transcriptional regulator
BC342_RS31530	COG0297	glycogen (starch) synthase activity
BC342_RS31535	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BC342_RS31540	COG3537	Alpha-1,2-mannosidase
BC342_RS31565	COG0154	amidase activity
BC342_RS31570	COG1609	Transcriptional regulator
BC342_RS31580	COG1175	transmembrane transport
BC342_RS31585	COG0395	ABC-type sugar transport system, permease component
BC342_RS31630	COG2843	Capsule synthesis protein
BC342_RS31645	COG0531	amino acid
BC342_RS31655	COG0726	polysaccharide deacetylase
BC342_RS31695	COG0583	DNA-binding transcription factor activity
BC342_RS31705	COG0583	DNA-binding transcription factor activity
BC342_RS31715	COG1053	succinate dehydrogenase
BC342_RS31720	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BC342_RS31745	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BC342_RS31755	COG3360	Dodecin
BC342_RS31760	COG2182	Extracellular solute-binding protein
BC342_RS31765	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
BC342_RS31770	COG0121	glutamine amidotransferase
BC342_RS31775	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BC342_RS31780	COG3572	ergothioneine biosynthetic process
BC342_RS31795	COG2084	Dehydrogenase
BC342_RS31800	COG3467	pyridoxamine 5'-phosphate
BC342_RS31820	COG0596	Alpha beta hydrolase
BC342_RS31840	COG1053	succinate dehydrogenase
BC342_RS31840	COG3976	FMN-binding domain protein
BC342_RS31860	COG4221	oxidoreductase activity
BC342_RS31885	COG1609	Transcriptional regulator
BC342_RS31890	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BC342_RS31900	COG0242	peptide deformylase activity
BC342_RS31940	COG0439	Biotin carboxylase
BC342_RS31950	COG1802	Transcriptional regulator
BC342_RS31965	COG0659	secondary active sulfate transmembrane transporter activity
BC342_RS31990	COG1725	Transcriptional regulator
BC342_RS31995	COG1131	(ABC) transporter
BC342_RS32010	COG1073	alpha beta
BC342_RS32030	COG1309	transcriptional regulator
BC342_RS32055	COG1695	Transcriptional regulator
BC342_RS32075	COG1250	3-hydroxyacyl-CoA dehydrogenase
BC342_RS32080	COG3246	L-lysine catabolic process to acetate
BC342_RS32090	COG1132	(ABC) transporter
BC342_RS32100	COG0494	nUDIX hydrolase
BC342_RS32110	COG0738	Major facilitator superfamily
BC342_RS32115	COG3226	Transcriptional regulator
BC342_RS32125	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BC342_RS32140	COG1216	Glycosyl transferase, family 2
BC342_RS32150	COG4310	Domain of unknown function (DUF2172)
BC342_RS32165	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BC342_RS32200	COG0367	asparagine synthase
BC342_RS32220	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BC342_RS32225	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BC342_RS32255	COG2186	Transcriptional regulator
BC342_RS32260	COG4948	Mandelate Racemase Muconate Lactonizing
BC342_RS32265	COG0800	Aldolase
BC342_RS32315	COG0702	epimerase
BC342_RS32320	COG1846	Transcriptional regulator
BC342_RS32325	COG2409	Drug exporters of the RND superfamily
BC342_RS32340	COG0668	transmembrane transport
BC342_RS32380	COG3540	Alkaline phosphatase
BC342_RS32400	COG1556	Lactate utilization protein
BC342_RS32405	COG1139	Iron-sulfur cluster binding protein
BC342_RS32410	COG0247	lactate metabolic process
BC342_RS32415	COG1070	Carbohydrate kinase
BC342_RS32420	COG1028	Short-chain dehydrogenase reductase Sdr
BC342_RS32420	COG3347	Dehydrogenase
BC342_RS32425	COG4952	isomerase
BC342_RS32430	COG1129	ABC transporter
BC342_RS32440	COG1172	Belongs to the binding-protein-dependent transport system permease family
BC342_RS32455	COG1609	Transcriptional regulator
BC342_RS32465	COG1357	PFAM Pentapeptide repeats (8 copies)
BC342_RS32470	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BC342_RS32470	COG2124	cytochrome p450
BC342_RS32475	COG1309	transcriptional regulator
BC342_RS32485	COG2706	6-phosphogluconolactonase activity
BC342_RS32590	COG2124	cytochrome p450
BC342_RS32600	COG0435	Glutathione S-transferase
BC342_RS32615	COG2124	cytochrome p450
BC342_RS32630	COG0667	Aldo Keto reductase
BC342_RS32650	COG1304	FMN binding
BC342_RS32665	COG2890	protein-(glutamine-N5) methyltransferase activity
BC342_RS32680	COG0248	Ppx GppA phosphatase
BC342_RS32750	COG1028	Short-chain dehydrogenase reductase Sdr
BC342_RS32760	COG1028	Short-chain dehydrogenase reductase Sdr
BC342_RS32790	COG1309	transcriptional regulator
BC342_RS32855	COG0673	inositol 2-dehydrogenase activity
BC342_RS32870	COG2508	Transcriptional regulator
BC342_RS32880	COG0411	ABC transporter
BC342_RS32925	COG1132	(ABC) transporter
BC342_RS32960	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BC342_RS32965	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BC342_RS32970	COG2080	2 iron, 2 sulfur cluster binding
BC342_RS32980	COG1028	Short-chain dehydrogenase reductase Sdr
BC342_RS33010	COG0477	Major facilitator Superfamily
BC342_RS33025	COG3290	protein histidine kinase activity
BC342_RS33060	COG0277	FAD linked oxidase domain protein
BC342_RS33085	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BC342_RS33090	COG0395	ABC-type sugar transport system, permease component
BC342_RS33115	COG2264	protein methyltransferase activity
BC342_RS33120	COG4221	oxidoreductase activity
BC342_RS33160	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BC342_RS33165	COG1120	ATPase activity
BC342_RS33175	COG0488	(ABC) transporter
BC342_RS33200	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BC342_RS33265	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
BC342_RS33325	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BC342_RS33350	COG0505	Belongs to the CarA family
BC342_RS33360	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BC342_RS33365	COG1191	sigma factor activity
BC342_RS33375	COG0783	Belongs to the Dps family
BC342_RS33380	COG0655	NAD(P)H dehydrogenase (quinone) activity
BC342_RS33385	COG2226	methyltransferase
BC342_RS33405	COG2018	Roadblock/LC7 domain
BC342_RS33420	COG2124	cytochrome p450
BC342_RS33430	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BC342_RS33440	COG2186	Transcriptional regulator
BC342_RS33455	COG0698	ribose 5-phosphate isomerase
BC342_RS33460	COG0149	triose-phosphate isomerase activity
BC342_RS33465	COG1082	Xylose isomerase domain protein TIM barrel
BC342_RS33470	COG2084	Dehydrogenase
BC342_RS33475	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BC342_RS33480	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BC342_RS33485	COG0142	geranyltranstransferase activity
BC342_RS33540	COG0745	RESPONSE REGULATOR receiver
BC342_RS33545	COG2205	protein histidine kinase activity
BC342_RS33550	COG2340	Cysteine-rich secretory protein family
BC342_RS33570	COG1196	nuclear chromosome segregation
BC342_RS33570	COG0739	heme binding
BC342_RS33570	COG0741	lytic transglycosylase activity
BC342_RS33575	COG2208	phosphoserine phosphatase activity
BC342_RS33580	COG1486	melibiose metabolic process
BC342_RS33585	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BC342_RS33590	COG0395	ABC-type sugar transport system, permease component
BC342_RS33625	COG1278	Cold shock
BC342_RS33640	COG3386	PFAM SMP-30 Gluconolaconase
BC342_RS33645	COG4221	oxidoreductase activity
BC342_RS33665	COG4221	oxidoreductase activity
BC342_RS33680	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BC342_RS33690	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BC342_RS33720	COG3486	L-lysine 6-monooxygenase (NADPH) activity
BC342_RS33725	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BC342_RS33730	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BC342_RS33735	COG1120	ATPase activity
BC342_RS33740	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BC342_RS33755	COG1132	(ABC) transporter
BC342_RS33760	COG2382	esterase
BC342_RS33810	COG0789	Transcriptional regulator
BC342_RS33820	COG0659	secondary active sulfate transmembrane transporter activity
BC342_RS33825	COG0346	lactoylglutathione lyase activity
BC342_RS33830	COG1120	ATPase activity
BC342_RS33835	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BC342_RS33845	COG0803	Belongs to the bacterial solute-binding protein 9 family
BC342_RS33870	COG0601	transmembrane transport
BC342_RS33875	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BC342_RS33880	COG0747	negative chemotaxis
BC342_RS33915	COG1472	Belongs to the glycosyl hydrolase 3 family
BC342_RS33925	COG1609	Transcriptional regulator
BC342_RS33930	COG0395	ABC-type sugar transport system, permease component
BC342_RS33935	COG1175	transmembrane transport
BC342_RS33945	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BC342_RS33980	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BC342_RS33985	COG1414	Transcriptional regulator
BC342_RS33990	COG0402	S-adenosylhomocysteine deaminase activity
BC342_RS33995	COG0477	Major facilitator Superfamily
BC342_RS34020	COG1984	allophanate hydrolase subunit 2
BC342_RS34025	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BC342_RS34030	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BC342_RS34045	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BC342_RS34055	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BC342_RS34070	COG2188	Transcriptional regulator
BC342_RS34075	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BC342_RS34080	COG0028	Belongs to the TPP enzyme family
BC342_RS34090	COG0477	Major facilitator Superfamily
BC342_RS34125	COG0667	Aldo Keto reductase
BC342_RS34160	COG1609	Transcriptional regulator
BC342_RS34190	COG0395	ABC-type sugar transport system, permease component
BC342_RS34200	COG0460	homoserine dehydrogenase
BC342_RS34215	COG1136	(ABC) transporter
BC342_RS34225	COG0577	efflux transmembrane transporter activity
BC342_RS34230	COG0745	RESPONSE REGULATOR receiver
BC342_RS34235	COG2205	protein histidine kinase activity
BC342_RS34260	COG1940	carbohydrate kinase activity
BC342_RS34265	COG3345	alpha-galactosidase
BC342_RS34275	COG0395	ABC-type sugar transport system, permease component
BC342_RS34280	COG1175	transmembrane transport
BC342_RS34290	COG1891	lyase activity
BC342_RS34305	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BC342_RS34325	COG0477	Major facilitator Superfamily
BC342_RS34335	COG1028	Short-chain dehydrogenase reductase Sdr
BC342_RS34340	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BC342_RS34355	COG1609	Transcriptional regulator
BC342_RS34360	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BC342_RS34365	COG0583	DNA-binding transcription factor activity
BC342_RS34370	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BC342_RS34415	COG2132	Multicopper oxidase
BC342_RS34420	COG2409	Drug exporters of the RND superfamily
BC342_RS34425	COG1309	transcriptional regulator
BC342_RS34440	COG0515	serine threonine protein kinase
BC342_RS34450	COG1902	pentaerythritol trinitrate reductase activity
BC342_RS34460	COG0515	serine threonine protein kinase
BC342_RS34470	COG1472	Belongs to the glycosyl hydrolase 3 family
BC342_RS34485	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BC342_RS34495	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BC342_RS34505	COG0667	Aldo Keto reductase
BC342_RS34515	COG0640	Transcriptional regulator
BC342_RS34520	COG1902	pentaerythritol trinitrate reductase activity
BC342_RS34545	COG3321	synthase
BC342_RS34545	COG0604	alcohol dehydrogenase
BC342_RS34545	COG0604	alcohol dehydrogenase
BC342_RS34545	COG3321	synthase
BC342_RS34565	COG3321	synthase
BC342_RS34565	COG0604	alcohol dehydrogenase
BC342_RS34570	COG2124	cytochrome p450
BC342_RS34585	COG1028	Short-chain dehydrogenase reductase Sdr
BC342_RS34610	COG1028	Short-chain dehydrogenase reductase Sdr
BC342_RS34650	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BC342_RS34715	COG3415	Transposase
BC342_RS34715	COG2801	Transposase and inactivated derivatives
BC342_RS34720	COG2815	serine threonine protein kinase
BC342_RS34720	COG0515	serine threonine protein kinase
BC342_RS34765	COG1857	crispr-associated protein
BC342_RS34990	COG3547	Transposase (IS116 IS110 IS902 family)
BC342_RS35005	COG1234	tRNA 3'-trailer cleavage
BC342_RS35080	COG0596	Alpha beta hydrolase